BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04818 (313 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4GYH-A nrPDB 651 0.0 4EIN-A nrPDB 580 e-166 4XSC-A nrPDB 443 e-125 5H3A-A nrPDB 441 e-124 5BY6-A nrPDB 423 e-119 4IQB-A nrPDB 417 e-117 5T0L-A nrPDB 395 e-110 4ECK-A nrPDB 395 e-110 3IRM-A nrPDB 382 e-107 2AAZ-A nrPDB 376 e-105 1CI7-A nrPDB 376 e-105 3KGB-A nrPDB 362 e-100 4DP3-A nrPDB 358 1e-99 3K2H-A nrPDB 356 8e-99 3DGA-C nrPDB 355 2e-98 1QZF-A nrPDB 355 2e-98 3IX6-A nrPDB 298 2e-81 6AUJ-A nrPDB 290 7e-79 6QXS-A nrPDB 283 5e-77 4FOG-A nrPDB 276 1e-74 4H0U-A nrPDB 261 2e-70 4F2V-A nrPDB 259 1e-69 4DQ1-A nrPDB 250 5e-67 1TSX-A nrPDB 248 3e-66 1TIS-A nrPDB 234 5e-62 3V8H-A nrPDB 184 6e-47 1BSF-A nrPDB 180 8e-46 5JP9-A nrPDB 55 4e-08 1B5E-A nrPDB 35 0.052 3AU7-A nrPDB 34 0.094 3AMU-A nrPDB 33 0.12 1ZCZ-A nrPDB 30 1.3 2ZB3-A nrPDB 30 1.8 4AZ4-A nrPDB 30 1.8 5OVR-A nrPDB 30 1.9 5LK8-B nrPDB 28 6.1 5K8K-A nrPDB 27 9.3 >4GYH-A nrPDB Length = 318 Score = 651 bits (1679), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/313 (100%), Positives = 313/313 (100%) Query: 1 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG Sbjct: 1 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60 Query: 61 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS Sbjct: 61 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120 Query: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC Sbjct: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180 Query: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI Sbjct: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240 Query: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG Sbjct: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300 Query: 301 YNPHPTIKMEMAV 313 YNPHPTIKMEMAV Sbjct: 301 YNPHPTIKMEMAV 313 >4EIN-A nrPDB Length = 307 Score = 580 bits (1494), Expect = e-166, Method: Compositional matrix adjust. Identities = 278/313 (88%), Positives = 292/313 (93%), Gaps = 6/313 (1%) Query: 1 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60 M V GSEL AQ+ AE P HGELQYL Q++HILRCG +K+DRTGTGTLSVFG Sbjct: 1 MLVVGSELQ-----SDAQQLSAEA-PRHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFG 54 Query: 61 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGV+IWDANGSRDFLDS Sbjct: 55 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDS 114 Query: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180 LGFS R+EGDLGPVYGFQWRHFGAEY+DM+SDYSGQGVDQLQ+VIDTIKTNPDDRRIIMC Sbjct: 115 LGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMC 174 Query: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240 AWNP+DLPLMALPPCHALCQFYVVN ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI Sbjct: 175 AWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 234 Query: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300 TGL+PGDF+HTLGDAHIYLNHIEPLKIQLQREPRPFPKL+ILRKVE IDDFK EDFQIEG Sbjct: 235 TGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEG 294 Query: 301 YNPHPTIKMEMAV 313 YNPHPTIKMEMAV Sbjct: 295 YNPHPTIKMEMAV 307 >4XSC-A nrPDB Length = 311 Score = 443 bits (1140), Expect = e-125, Method: Compositional matrix adjust. Identities = 199/277 (71%), Positives = 237/277 (85%) Query: 29 GELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEEL 88 GELQYL Q+ ILR GVRK DRTG GTLS+FGMQARY+LR+EFPLLTTKRVFW+ V+EEL Sbjct: 33 GELQYLKQVDDILRYGVRKRDRTGIGTLSLFGMQARYNLRNEFPLLTTKRVFWRAVVEEL 92 Query: 89 LWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRD 148 LWFI+GST++KEL++K + IWD GS FL+ GF R GDLGP+YGFQWRHFGAEY+D Sbjct: 93 LWFIRGSTDSKELAAKDIHIWDIYGSSKFLNRNGFHKRHTGDLGPIYGFQWRHFGAEYKD 152 Query: 149 MESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSEL 208 +S+Y QG+DQLQ VIDTIKTNP+ RR+I+ +WNP+D+PLM LPPCH LCQFYV N EL Sbjct: 153 CQSNYLQQGIDQLQTVIDTIKTNPESRRMIISSWNPKDIPLMVLPPCHTLCQFYVANGEL 212 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQ 268 SCQ+YQRSGDMGLGVPFNIA YALLTY++AH+TGLK GD IHT+GDAHIYLNHI+ LK+Q Sbjct: 213 SCQVYQRSGDMGLGVPFNIAGYALLTYIVAHVTGLKTGDLIHTMGDAHIYLNHIDALKVQ 272 Query: 269 LQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHP 305 L R P+PFP L+I+R V I+DFK +DFQ++GYNPHP Sbjct: 273 LARSPKPFPCLKIIRNVTDINDFKWDDFQLDGYNPHP 309 >5H3A-A nrPDB Length = 283 Score = 441 bits (1135), Expect = e-124, Method: Compositional matrix adjust. Identities = 203/283 (71%), Positives = 237/283 (83%) Query: 27 PHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLE 86 PH ELQYL Q++ IL G + DRTG GTLS+FGMQARYSLRD FPLLTTKRVFW+GV++ Sbjct: 1 PHEELQYLRQLREILCRGSDRLDRTGIGTLSLFGMQARYSLRDHFPLLTTKRVFWRGVVQ 60 Query: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146 ELLWF+KGST+++ELS GVKIWD NGSR+FL G + R EGDLGPVYGFQWRHFGA Y Sbjct: 61 ELLWFLKGSTDSRELSRTGVKIWDKNGSREFLAGRGLAHRREGDLGPVYGFQWRHFGAAY 120 Query: 147 RDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNS 206 D ++DY+GQG DQL ++D IK NP DRRIIMCAWNP DL LMALPPCH LCQFYV + Sbjct: 121 VDADADYTGQGFDQLSYIVDLIKNNPHDRRIIMCAWNPADLSLMALPPCHLLCQFYVADG 180 Query: 207 ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 ELSCQLYQRSGDMGLGVPFNIASY+LLTYM+AH+TGL+PG+FIHTLGDAHIY HIEPL+ Sbjct: 181 ELSCQLYQRSGDMGLGVPFNIASYSLLTYMLAHVTGLRPGEFIHTLGDAHIYKTHIEPLR 240 Query: 267 IQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKM 309 +QL R PRPFP+L ILR V +++F +DF++ Y PHPTI+M Sbjct: 241 LQLTRTPRPFPRLEILRSVSSMEEFTPDDFRLVDYCPHPTIRM 283 >5BY6-A nrPDB Length = 307 Score = 423 bits (1087), Expect = e-119, Method: Compositional matrix adjust. Identities = 196/285 (68%), Positives = 228/285 (80%), Gaps = 1/285 (0%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLEEL 88 EL YL Q++ I+ GVRK+DRTG GTLS FG Q+RY LRD+ FPLLTTKRVFW+GV+EEL Sbjct: 23 ELNYLNQLKDIIDHGVRKNDRTGIGTLSTFGTQSRYCLRDDIFPLLTTKRVFWRGVVEEL 82 Query: 89 LWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRD 148 LWFI GSTNAK+LS K V IWD N SR+FLDS G EEGDLGPVYGFQWRHFG Y Sbjct: 83 LWFISGSTNAKQLSEKNVNIWDGNSSREFLDSRGLYNYEEGDLGPVYGFQWRHFGCPYSS 142 Query: 149 MESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSEL 208 M +DY G+G DQLQ+ I I+ P+ RRIIM AWNP DL +ALPPCH QFYV + EL Sbjct: 143 MTADYKGKGYDQLQQCIKMIREEPESRRIIMTAWNPCDLEKVALPPCHCFVQFYVADGEL 202 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQ 268 SCQ+YQRS DMGLGVPFNIASY+LLT MIAHIT LKPG FIHT+GDAH+YL H++ LK+Q Sbjct: 203 SCQMYQRSADMGLGVPFNIASYSLLTRMIAHITSLKPGFFIHTIGDAHVYLTHVDALKVQ 262 Query: 269 LQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 ++R+PRPFPKL+ILR VE IDDF+AEDF++ Y P+P I M MAV Sbjct: 263 MERKPRPFPKLKILRNVENIDDFRAEDFELINYKPYPKISMPMAV 307 >4IQB-A nrPDB Length = 315 Score = 417 bits (1072), Expect = e-117, Method: Compositional matrix adjust. Identities = 194/285 (68%), Positives = 225/285 (78%), Gaps = 1/285 (0%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRD-EFPLLTTKRVFWKGVLEEL 88 E +YL Q++ ILR G R+DDRTGTGT+S+FGMQ++Y LR+ PLLTTKRV+WKGVLEEL Sbjct: 31 EYKYLKQVEQILREGTRRDDRTGTGTISIFGMQSKYCLRNGTIPLLTTKRVYWKGVLEEL 90 Query: 89 LWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRD 148 LWFI GST+ K L K VKIW+ NG R FLD+LGF++REEGDLGPVYGFQWRHFGA+Y D Sbjct: 91 LWFISGSTDGKLLMEKNVKIWEKNGDRAFLDNLGFTSREEGDLGPVYGFQWRHFGAKYVD 150 Query: 149 MESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSEL 208 +DYSGQGVDQL VI IK PD RRIIM AWNP DL M LPPCH +CQFYV N EL Sbjct: 151 CHTDYSGQGVDQLAEVIRQIKEQPDSRRIIMSAWNPSDLGQMVLPPCHTMCQFYVDNGEL 210 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQ 268 SCQLYQRSGDMGLGVPFN+ASY LLT+MIA + GLKPG +HTLGDAH+Y NH++ LKIQ Sbjct: 211 SCQLYQRSGDMGLGVPFNLASYGLLTHMIAKVCGLKPGTLVHTLGDAHVYSNHVDALKIQ 270 Query: 269 LQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 L REP FPK+R R V IDDF ++ ++ Y HP I M+MAV Sbjct: 271 LDREPYAFPKIRFTRDVASIDDFTSDMIALDDYKCHPKIPMDMAV 315 >5T0L-A nrPDB Length = 566 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 187/289 (64%), Positives = 220/289 (76%), Gaps = 3/289 (1%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL I I+ G DDRTG G +S FG RYSL FPLLTTKRVFWKGVLEE Sbjct: 278 HEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEE 337 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFI+G TNA LS KGVKIWD N +R+FLDS RE GD+GP YGFQWRHFGA Y+ Sbjct: 338 LLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYK 397 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVN-S 206 DM +DY+GQGVDQL+ VI ++TNP DRR++M AWNP L MALPPCH LCQFYV + Sbjct: 398 DMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQK 457 Query: 207 ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 ELSC +YQRS D+GLGVPFNIASY+LLT M+AH+ LKP +FIH +G+ H+Y NH+E LK Sbjct: 458 ELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALK 517 Query: 267 IQLQREPRPFPKLRILRK--VEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 QL+REPRPFP + IL K +++IDDF AEDF++ GY PH I+MEMAV Sbjct: 518 EQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 566 >4ECK-A nrPDB Length = 610 Score = 395 bits (1014), Expect = e-110, Method: Compositional matrix adjust. Identities = 187/289 (64%), Positives = 220/289 (76%), Gaps = 3/289 (1%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL I I+ G DDRTG G +S FG RYSL FPLLTTKRVFWKGVLEE Sbjct: 322 HEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEE 381 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFI+G TNA LS KGVKIWD N +R+FLDS RE GD+GP YGFQWRHFGA Y+ Sbjct: 382 LLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYK 441 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVN-S 206 DM +DY+GQGVDQL+ VI ++TNP DRR++M AWNP L MALPPCH LCQFYV + Sbjct: 442 DMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQK 501 Query: 207 ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 ELSC +YQRS D+GLGVPFNIASY+LLT M+AH+ LKP +FIH +G+ H+Y NH+E LK Sbjct: 502 ELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALK 561 Query: 267 IQLQREPRPFPKLRILRK--VEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 QL+REPRPFP + IL K +++IDDF AEDF++ GY PH I+MEMAV Sbjct: 562 EQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 610 >3IRM-A nrPDB Length = 521 Score = 382 bits (982), Expect = e-107, Method: Compositional matrix adjust. Identities = 180/285 (63%), Positives = 217/285 (76%), Gaps = 1/285 (0%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLEEL 88 E QYL + I+R G K DRTG GTLS+FG Q R+SLR+ PLLTTKRVFW+GV EEL Sbjct: 237 EEQYLSLVDRIIREGNVKHDRTGVGTLSIFGAQMRFSLRNNRLPLLTTKRVFWRGVCEEL 296 Query: 89 LWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRD 148 LWF++G T AK+LS KGV IWD NGSR FLDS G + EE DLGPVYGFQWRHFGA Y Sbjct: 297 LWFLRGETYAKKLSDKGVHIWDDNGSRAFLDSRGLTEYEEMDLGPVYGFQWRHFGAAYTH 356 Query: 149 MESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSEL 208 +++Y GQGVDQ++ +++T+KTNPDDRR++ AWNP LP MALPPCH L QFYV N EL Sbjct: 357 HDANYDGQGVDQIKAIVETLKTNPDDRRMLFTAWNPSALPRMALPPCHLLAQFYVSNGEL 416 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQ 268 SC LYQRS DMGLGVPFNIASYALLT +IA TGL+PG+ +HTLGDAH+Y NH+EP Q Sbjct: 417 SCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYSNHVEPCNEQ 476 Query: 269 LQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 L+R PR FP L R+ E ++D++ D ++ Y P+P I M+MAV Sbjct: 477 LKRVPRAFPYLVFRREREFLEDYEEGDMEVIDYAPYPPISMKMAV 521 >2AAZ-A nrPDB Length = 317 Score = 376 bits (966), Expect = e-105, Method: Compositional matrix adjust. Identities = 187/310 (60%), Positives = 227/310 (73%), Gaps = 14/310 (4%) Query: 18 QERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQA-RYSLRDE-FPLLT 75 QE++ P H E QYL I+ I+ G + DRTGTGT+++F + R+SL D PLLT Sbjct: 8 QEKNQRSNPDHEEYQYLDLIRRIINVGEVRPDRTGTGTVALFAPPSFRFSLADNTLPLLT 67 Query: 76 TKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVY 135 TKRVF +GV+ ELLWF+ G T+AK LSS+GV IWD NGS++FL+ +G R EGDLGPVY Sbjct: 68 TKRVFLRGVIAELLWFVSGCTDAKMLSSQGVGIWDGNGSKEFLEKVGLGHRREGDLGPVY 127 Query: 136 GFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPC 195 GFQWRHFGAEY D + DY G+GVDQLQRVIDTIK NP DRRII+ AWNP+DLPLMALPPC Sbjct: 128 GFQWRHFGAEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPKDLPLMALPPC 187 Query: 196 HALCQFYV---------VNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPG 246 H CQF+V +LSC +YQRS D+GLGVPFNIASYALLT+MIA IT +P Sbjct: 188 HMFCQFFVSLPPADSPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHMIALITDTEPH 247 Query: 247 DFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEK---IDDFKAEDFQIEGYNP 303 +FI +GDAH+Y +H+EPLK QL+REPR FPKL+ R E+ ID FK EDF +EGY P Sbjct: 248 EFILQMGDAHVYRDHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKVEDFVVEGYKP 307 Query: 304 HPTIKMEMAV 313 I M+M+ Sbjct: 308 WGKIDMKMSA 317 >1CI7-A nrPDB Length = 297 Score = 376 bits (966), Expect = e-105, Method: Compositional matrix adjust. Identities = 180/292 (61%), Positives = 223/292 (76%), Gaps = 8/292 (2%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQ-ARYSLRDE-FPLLTTKRVFWKGVLEE 87 E QYL +Q+I+ G + DRTGTGTLSVF ++SLR++ FPLLTTKRVF +GV+EE Sbjct: 6 EQQYLNLVQYIINHGEDRPDRTGTGTLSVFAPSPLKFSLRNKTFPLLTTKRVFIRGVIEE 65 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFI+G T++ +L K + IWDANGSR++LDS+G + R+EGDLGP+YGFQWRHFGAEY Sbjct: 66 LLWFIRGETDSLKLREKNIHIWDANGSREYLDSIGLTKRQEGDLGPIYGFQWRHFGAEYI 125 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYV---- 203 D +++Y GQGVDQL +I I+T+P DRR+I+ AWNP DL MALPPCH CQFYV Sbjct: 126 DCKTNYIGQGVDQLANIIQKIRTSPYDRRLILSAWNPADLEKMALPPCHMFCQFYVHIPS 185 Query: 204 --VNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNH 261 ELSCQLYQRS DMGLGVPFNIASYALLT MIAH+ L PGDFIH +GD HIY +H Sbjct: 186 NNHRPELSCQLYQRSCDMGLGVPFNIASYALLTCMIAHVCDLDPGDFIHVMGDCHIYKDH 245 Query: 262 IEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 IE L+ QL R PRPFP L + R + I+DF +DF I+ Y+P+ TIKM+M++ Sbjct: 246 IEALQQQLTRSPRPFPTLSLNRSITDIEDFTLDDFNIQNYHPYETIKMKMSI 297 >3KGB-A nrPDB Length = 294 Score = 362 bits (928), Expect = e-100, Method: Compositional matrix adjust. Identities = 173/291 (59%), Positives = 221/291 (75%), Gaps = 4/291 (1%) Query: 26 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGV 84 P H E QYL ++HIL G R+ DRTGTGTLSVFG R+SL D FPLLTT+RVF++GV Sbjct: 5 PRHPEHQYLDLVKHILENGARRMDRTGTGTLSVFGATMRFSLEDNTFPLLTTRRVFYRGV 64 Query: 85 LEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGA 144 +EELL+F++G T++K L KGV+IW+ NG++ FL S+G REEGDLGP+YGFQWRHFGA Sbjct: 65 VEELLFFLRGETDSKVLEKKGVRIWEKNGAKQFLQSVGID-REEGDLGPIYGFQWRHFGA 123 Query: 145 EYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVV 204 Y S Y G+GVDQ+ I I+ NP RRI++ AWNP DL MALPPCH L QF V Sbjct: 124 RYETSASSYEGKGVDQIASAIAAIRANPASRRIVVSAWNPTDLGSMALPPCHVLFQFNVT 183 Query: 205 NSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEP 264 + +LSC +YQRSGDMGLGVPFNIASY+LLT ++AH+TGL+PG+F+H LGDAH+YL+H++ Sbjct: 184 DGKLSCAMYQRSGDMGLGVPFNIASYSLLTILVAHLTGLQPGEFVHFLGDAHVYLDHVDS 243 Query: 265 LKIQLQREPRPFPKLRILRKVEKI--DDFKAEDFQIEGYNPHPTIKMEMAV 313 L+ Q+QR PR FPKL + K + + F+ EDF++ GY+PHP IKM M+ Sbjct: 244 LRQQIQRPPRAFPKLFVSPKGPRTEPEHFQYEDFELVGYDPHPAIKMNMSA 294 >4DP3-A nrPDB Length = 608 Score = 358 bits (919), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 161/299 (53%), Positives = 210/299 (70%) Query: 14 PPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPL 73 P Q ++ H E QYL I I+ G ++ DRTG G LS FG ++ L FPL Sbjct: 309 PNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPL 368 Query: 74 LTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGP 133 LTTK++F +G++EELLWFI+G TN L +K V+IW+ANG+R+FLD+ RE DLGP Sbjct: 369 LTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGP 428 Query: 134 VYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALP 193 +YGFQWRHFGAEY +M +Y +GVDQL+ +I+ IK +P RRI++CAWN +DL MALP Sbjct: 429 IYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALP 488 Query: 194 PCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLG 253 PCH LCQFYV + +LSC +YQRS D+GLGVPFNIASY++ T+MIA + L+P FIH LG Sbjct: 489 PCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLG 548 Query: 254 DAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 312 +AH+Y NHI+ LKIQL R P PFP L++ ++ I+DF DF I+ Y H I M+MA Sbjct: 549 NAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMA 607 >3K2H-A nrPDB Length = 511 Score = 356 bits (913), Expect = 8e-99, Method: Compositional matrix adjust. Identities = 160/285 (56%), Positives = 209/285 (73%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL + +L GV K +RTGT S FG Q R+ L FPLLTTK+V + ++EE Sbjct: 226 HEEFQYLDILADVLSHGVLKPNRTGTDAYSKFGYQMRFDLSRSFPLLTTKKVALRSIIEE 285 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFIKGSTN +L +K V+IW+ NG RDFLD GF+ REE DLGP+YGFQWRHFGAEY Sbjct: 286 LLWFIKGSTNGNDLLAKNVRIWELNGRRDFLDKNGFTDREEHDLGPIYGFQWRHFGAEYL 345 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSE 207 DM +DY+G+G+DQL +I+ IKTNP+DRR+I+C+WN DL MALPPCH QFYV +++ Sbjct: 346 DMHADYTGKGIDQLAEIINRIKTNPNDRRLIVCSWNVSDLKKMALPPCHCFFQFYVSDNK 405 Query: 208 LSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKI 267 LSC ++QRS D+GLGVPFNIASY++LT M+A + GL G+F+H L DAHIY++H++ + Sbjct: 406 LSCMMHQRSCDLGLGVPFNIASYSILTAMVAQVCGLGLGEFVHNLADAHIYVDHVDAVTT 465 Query: 268 QLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 312 Q+ R P PFP+LR+ + I+DF +D +E Y HP I M M+ Sbjct: 466 QIARIPHPFPRLRLNPDIRNIEDFTIDDIVVEDYVSHPPIPMAMS 510 >3DGA-C nrPDB Length = 328 Score = 355 bits (910), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 161/299 (53%), Positives = 210/299 (70%) Query: 14 PPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPL 73 P Q ++ H E QYL I I+ G ++ DRTG G LS FG ++ L FPL Sbjct: 29 PNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPL 88 Query: 74 LTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGP 133 LTTK++F +G++EELLWFI+G TN L +K V+IW+ANG+R+FLD+ RE DLGP Sbjct: 89 LTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGP 148 Query: 134 VYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALP 193 +YGFQWRHFGAEY +M +Y +GVDQL+ +I+ IK +P RRI++CAWN +DL MALP Sbjct: 149 IYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALP 208 Query: 194 PCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLG 253 PCH LCQFYV + +LSC +YQRS D+GLGVPFNIASY++ T+MIA + L+P FIH LG Sbjct: 209 PCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLG 268 Query: 254 DAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 312 +AH+Y NHI+ LKIQL R P PFP L++ ++ I+DF DF I+ Y H I M+MA Sbjct: 269 NAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMA 327 >1QZF-A nrPDB Length = 521 Score = 355 bits (910), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 162/287 (56%), Positives = 205/287 (71%), Gaps = 1/287 (0%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL + +L G +++RTG T S+FG R+ +R+ FPLLTTK+V + + EE Sbjct: 235 HYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEE 294 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 L+WFIKG TN L K V IW NGS+++L+ +G REE DLGP+YGFQWRH+ EY+ Sbjct: 295 LIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYK 354 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSE 207 M DY+G GVDQL ++I+T+K NP DRR I+ AWNP L MALPPCH L Q+YV N Sbjct: 355 TMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDN 414 Query: 208 -LSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 LSC LYQRS D+GLG PFNIASYA+LT M+A + G +PG+ +GDAHIY NH+ LK Sbjct: 415 CLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLK 474 Query: 267 IQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 QL R PRPFP+L+ RKVE I+DFK ED ++ GY P+PTIKM+MAV Sbjct: 475 EQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 521 >3IX6-A nrPDB Length = 360 Score = 298 bits (762), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 149/285 (52%), Positives = 186/285 (65%), Gaps = 20/285 (7%) Query: 29 GELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEEL 88 G YL +QH+L GV +DDRTGTGT SVFG Q R+ L + FP+LTTK++ + ++ EL Sbjct: 96 GMRTYLDLLQHVLDHGVDRDDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHEL 155 Query: 89 LWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRD 148 LWF+KG TN L GV IWD E GDLGPVYG+QWR + A Sbjct: 156 LWFLKGDTNIAYLKENGVTIWDEWAD------------ENGDLGPVYGYQWRSWPAP--- 200 Query: 149 MESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSEL 208 G+ +DQ+ ++ + TNP RR+I+ AWNP + MALPPCH L QFYV N L Sbjct: 201 -----DGRHIDQIANLLKMLHTNPQSRRLIVSAWNPALVDEMALPPCHCLFQFYVANGRL 255 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQ 268 SCQLYQRS D+ LGVPFNIASYALLT MIA +TGLKPG+FIHTLGDAHIY NH E ++Q Sbjct: 256 SCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPGEFIHTLGDAHIYSNHFEQARLQ 315 Query: 269 LQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 L R P+ P + I V+ + F+ EDF+++GY PTIK +AV Sbjct: 316 LTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPTIKAPIAV 360 >6AUJ-A nrPDB Length = 272 Score = 290 bits (741), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 147/283 (51%), Positives = 184/283 (65%), Gaps = 22/283 (7%) Query: 32 QYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWF 91 YL +Q IL G K DRTGTGT S+FG Q RY L FPL+TTK+V K ++ ELLWF Sbjct: 11 NYLHLLQDILDNGSDKTDRTGTGTRSLFGYQLRYDLSKGFPLVTTKKVHLKSIIYELLWF 70 Query: 92 IKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHF-GAEYRDME 150 +KG TN K L GV IWD E GDLGPVYG QWR + GA+ Sbjct: 71 LKGDTNIKYLKDNGVSIWDEWAD------------ENGDLGPVYGAQWRSWRGAD----- 113 Query: 151 SDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSC 210 + VDQ+ VID IK NPD RR+I+ AWN ++P MAL PCHA+ QFYV + +LS Sbjct: 114 ----NKVVDQISEVIDQIKKNPDSRRLIVSAWNVAEIPNMALAPCHAMFQFYVADGKLSL 169 Query: 211 QLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQ 270 QLYQRS D+ LGVPFNIASYALL M+A +TGL+ GD++H+ GD HIY NH E + QL Sbjct: 170 QLYQRSADVFLGVPFNIASYALLLMMVAQVTGLQVGDYVHSFGDVHIYNNHFEQVNRQLS 229 Query: 271 REPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 R+P+P P +++ V+ I DFK EDF++ Y+PHP IK +A+ Sbjct: 230 RDPKPLPVMKLNPDVKDIFDFKFEDFELLNYDPHPGIKAPVAI 272 >6QXS-A nrPDB Length = 315 Score = 283 bits (725), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 154/322 (47%), Positives = 194/322 (60%), Gaps = 46/322 (14%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 E YL + IL G K+DRTGTGT S+FG Q R+ L FPLLTTKRV + + ELL Sbjct: 2 EEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKRVPFGLIKSELL 61 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGF--------------------STREE- 128 WF+KG TN + L + IWD ++ S + +EE Sbjct: 62 WFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDMTDFGHRVLQDPAFAEQYKEEH 121 Query: 129 -----------------GDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTN 171 G+LG +YG QWRH+ E +D G +DQL VI+ IKTN Sbjct: 122 QKFCDAILNDAEFAEKYGELGNIYGAQWRHW--ETKD------GSFIDQLANVIEMIKTN 173 Query: 172 PDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYA 231 PD RR+I+ AWNP D+P MALPPCH + QFYV +LSCQLYQRS D+ LGVPFNIASYA Sbjct: 174 PDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVNEGKLSCQLYQRSADVFLGVPFNIASYA 233 Query: 232 LLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDF 291 LLT++IAH TGL+ G+F+HTLGDAH+Y NH+E ++ QL RE R FP L + + DF Sbjct: 234 LLTHLIAHETGLEVGEFVHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDF 293 Query: 292 KAEDFQIEGYNPHPTIKMEMAV 313 ED ++EGY+PHPTIK +AV Sbjct: 294 DMEDIKVEGYDPHPTIKAPIAV 315 >4FOG-A nrPDB Length = 263 Score = 276 bits (705), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 141/281 (50%), Positives = 182/281 (64%), Gaps = 21/281 (7%) Query: 33 YLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFI 92 Y ++ +L G K DRTGTGT S+FG Q RY L FPLLTTK+V +K V ELLWF+ Sbjct: 4 YEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFL 63 Query: 93 KGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESD 152 +G +N L GV IWD S + G+LGP+YG QWR + A Sbjct: 64 RGDSNIGWLHEHGVTIWDEWAS------------DTGELGPIYGVQWRSWPAP------- 104 Query: 153 YSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQL 212 SG+ +DQ+ +D ++T+PD RRII+ AWN ++ MALPPCHA QFYV + LSCQL Sbjct: 105 -SGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQL 163 Query: 213 YQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQRE 272 YQRS D+ LGVPFNIASYALLT+M+A GL G+FI T GD HIY NH+E +++QL RE Sbjct: 164 YQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSRE 223 Query: 273 PRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 PRP+PKL +L + I ++ ED ++ Y+PHP IK +AV Sbjct: 224 PRPYPKL-LLADRDSIFEYTYEDIVVKNYDPHPAIKAPVAV 263 >4H0U-A nrPDB Length = 266 Score = 261 bits (667), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 135/281 (48%), Positives = 179/281 (63%), Gaps = 21/281 (7%) Query: 33 YLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFI 92 Y ++ I G KDDRTGTGT S+FG Q R+ L + FPLLTTK+V + V+ ELLWF+ Sbjct: 7 YEDLLRKIAEEGSHKDDRTGTGTTSLFGQQIRFDLNEGFPLLTTKKVHFHSVVGELLWFL 66 Query: 93 KGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESD 152 +G +N K L ++IW+ ++ D E+G+LGPVYG QWR + Sbjct: 67 QGDSNVKWLQDNNIRIWN-----EWAD-------EDGELGPVYGVQWRSWPTP------- 107 Query: 153 YSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQL 212 G+ +DQ+ ++T++ NPD RR I+ AWN +L MALPPCH L Q YV + +LSCQL Sbjct: 108 -DGRHIDQISGALETLRNNPDSRRNIVSAWNVSELENMALPPCHLLFQLYVADGKLSCQL 166 Query: 213 YQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQRE 272 YQRS DM LGVPFNIASYALLT+M A GL+ G+FI T GD HIY NH E + QL RE Sbjct: 167 YQRSADMFLGVPFNIASYALLTHMFAQQAGLEVGEFIWTGGDCHIYDNHKEQVAEQLSRE 226 Query: 273 PRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 RP+P L L K + ++ +D + GY+PHP I+ ++AV Sbjct: 227 ARPYPTLE-LNKAASMFEYSFDDITVSGYDPHPLIRGKVAV 266 >4F2V-A nrPDB Length = 272 Score = 259 bits (662), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 135/282 (47%), Positives = 178/282 (63%), Gaps = 20/282 (7%) Query: 32 QYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWF 91 QYL +Q +L G +K+DRTGTGTLS+FG Q R++L+D FPL+TTKR + ++ LLWF Sbjct: 3 QYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHLLLWF 62 Query: 92 IKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMES 151 ++G TN L V I D E GDLGPV+G QWR + Sbjct: 63 LQGDTNIAYLHENNVTILDEWAD------------ENGDLGPVHGKQWRAWPTP------ 104 Query: 152 DYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQ 211 G+ +DQ+ V++ +K +PD RRII+ AWN +L MA P HA QFYV + +LSCQ Sbjct: 105 --DGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMANAPSHAFFQFYVADGKLSCQ 162 Query: 212 LYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQR 271 LY RS D+ L +PF IAS ALL +M+A L+ GDF+ T GD H+Y NH++ +QL R Sbjct: 163 LYARSEDVFLSLPFAIASGALLVHMMAQQCDLEVGDFVMTGGDTHLYSNHMDQTHLQLSR 222 Query: 272 EPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 EPRP PKL I RK E I D++ EDF+IEGY+PHP IK +A+ Sbjct: 223 EPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI 264 >4DQ1-A nrPDB Length = 321 Score = 250 bits (639), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 139/319 (43%), Positives = 178/319 (55%), Gaps = 47/319 (14%) Query: 33 YLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFI 92 Y + +L G ++DRT TGT+S FG Q R+ L FPLLTTK+V +K V ELLWFI Sbjct: 12 YHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLLTTKKVSFKLVATELLWFI 71 Query: 93 KGSTNAKELSSKGVKIWDANGSRDFLDSLGFS---------------------------- 124 KG TN + L IW+ +++ S ++ Sbjct: 72 KGDTNIQYLLKYNNNIWNEWAFENYIKSDEYNGPDMTDFGHRALSDPEFNEQYKEQMKQF 131 Query: 125 ----------TREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDD 174 ++ GDLG VYG QWR + D G DQL+ VI+ IK NPD Sbjct: 132 KQRILEDDTFAKQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDS 183 Query: 175 RRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLT 234 RR I+ AWNP ++ MALPPCH + QFYV + +LSCQLYQRS D+ LGVPFNIASYALLT Sbjct: 184 RRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLT 243 Query: 235 YMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAE 294 ++IA GL+ G+F+HT GDAHIY NHI+ ++ QL RE P L+I + I D E Sbjct: 244 HLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKI-NSDKSIFDINYE 302 Query: 295 DFQIEGYNPHPTIKMEMAV 313 D +I Y HP IK +AV Sbjct: 303 DLEIVDYESHPAIKAPIAV 321 >1TSX-A nrPDB Length = 316 Score = 248 bits (632), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 140/322 (43%), Positives = 180/322 (55%), Gaps = 46/322 (14%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 E YL + +L G K DRT TGT S+FG Q R+ L FPLLTTK+V + + ELL Sbjct: 3 EQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTKKVPFGLIKSELL 62 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFL--------DSLGFSTREE------------- 128 WF+ G TN + L IWD ++ D F R + Sbjct: 63 WFLHGDTNIRFLLQHRNHIWDEWAFEKWVKSDEYHGPDMTDFGHRSQKDPEFAAVYHEEM 122 Query: 129 -----------------GDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTN 171 GDLG VYG QWR + G +DQL VI+ IKT+ Sbjct: 123 AKFDDRVLHDDAFAAKYGDLGLVYGSQWRAWHTS--------KGDTIDQLGDVIEQIKTH 174 Query: 172 PDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYA 231 P R +I+ AWNP D+P MALPPCH L QFYV + +LS QLYQRS D+ LGVPFNIASYA Sbjct: 175 PYSRELIVSAWNPEDVPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYA 234 Query: 232 LLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDF 291 LLT+++AH GL+ G+FIHT GDAH+Y+NH++ +K QL R PRP P L++ I DF Sbjct: 235 LLTHLVAHECGLEVGEFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDF 294 Query: 292 KAEDFQIEGYNPHPTIKMEMAV 313 +D ++ Y+P+P IK +AV Sbjct: 295 DMKDIKLLNYDPYPAIKAPVAV 316 >1TIS-A nrPDB Length = 286 Score = 234 bits (596), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 131/301 (43%), Positives = 172/301 (57%), Gaps = 36/301 (11%) Query: 32 QYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWF 91 QY I+ I G DDRTGTGT+++FG + R+ L FP +TTK++ WK + EL+WF Sbjct: 3 QYQDLIKDIFENGYETDDRTGTGTIALFGSKLRWDLTKGFPAVTTKKLAWKACIAELIWF 62 Query: 92 IKGSTNAKELS-------SKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGA 144 + GSTN +L +G +WD N D LG+ + G+LGP+YG QWR FG Sbjct: 63 LSGSTNVNDLRLIQHDSLIQGKTVWDENYENQAKD-LGYHS---GELGPIYGKQWRDFG- 117 Query: 145 EYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVV 204 GVDQ+ VID IK P+DRR I+ AWNP +L MALPPCH QF V Sbjct: 118 ------------GVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVR 165 Query: 205 NSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEP 264 N L Q YQRS D+ LG+PFNIASYA L +++A + L PGD I + G+ HIY+NH+E Sbjct: 166 NGYLDLQWYQRSVDVFLGLPFNIASYATLVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQ 225 Query: 265 LKIQLQREPRPFP---------KLRILRKVEKID---DFKAEDFQIEGYNPHPTIKMEMA 312 K L+REP+ K R L E++ + +DF + Y HP IK +MA Sbjct: 226 CKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKLRPKDFVLNNYVSHPPIKGKMA 285 Query: 313 V 313 V Sbjct: 286 V 286 >3V8H-A nrPDB Length = 327 Score = 184 bits (466), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 112/326 (34%), Positives = 164/326 (50%), Gaps = 39/326 (11%) Query: 27 PHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLE 86 P QYL ++ IL G + +RTG T+ + G R+ L+ FP +TTK++ +K + Sbjct: 2 PGSMKQYLDLVRTILDTGTWQSNRTGIRTIGIPGAMLRFDLQQGFPAVTTKKLAFKSAIG 61 Query: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHF-GAE 145 EL+ F++ + +A E + G K+WDAN + + R DLG VYG QWR + G + Sbjct: 62 ELVGFLRATRSAAEFRALGCKVWDANANENAQWLANPYRRGADDLGDVYGVQWRRWPGYK 121 Query: 146 YRDMESDYS-------------------------GQGVDQLQRVIDTIKTNPDDRRIIMC 180 D +D + +DQL+ +DTI +P RRI+ Sbjct: 122 VLDAHADAQIADATSRGFRIVARFEEGGADKVLLHKAIDQLRDCLDTIVRDPSSRRILFH 181 Query: 181 AWNPRDLPLMALPPCHALCQFY--VVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIA 238 WNP L +ALP CH L QF V E+S LY RS D+GLG PFN+A A L ++ Sbjct: 182 GWNPAVLDEIALPACHLLYQFLPNVERREISLCLYIRSNDVGLGTPFNLAEGAALLTLVG 241 Query: 239 HITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKV-----------EK 287 +TG P F + +GDAHIY N ++ LK QL+REP P+L + +V + Sbjct: 242 RLTGYSPRWFTYFIGDAHIYENQLDMLKQQLEREPFESPRLELAERVPDYAKTGKYEPQW 301 Query: 288 IDDFKAEDFQIEGYNPHPTIKMEMAV 313 ++ + DF + GY H + MAV Sbjct: 302 LERVEPSDFTLVGYRHHEPLSAPMAV 327 >1BSF-A nrPDB Length = 278 Score = 180 bits (456), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 107/293 (36%), Positives = 156/293 (53%), Gaps = 31/293 (10%) Query: 32 QYLGQIQHILRCGVRKD----------DRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFW 81 QY I+ I+ G+ + D T TLSV Q R+ E P+LTTK+V W Sbjct: 6 QYNSIIKDIINNGISDEEFDVRTKWDSDGTPAHTLSVISKQMRFD-NSEVPILTTKKVAW 64 Query: 82 KGVLEELLWFIK-GSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWR 140 K ++ELLW + S + +L+ GV IWD +E+G +G YGFQ Sbjct: 65 KTAIKELLWIWQLKSNDVNDLNMMGVHIWDQ------------WKQEDGTIGHAYGFQ-- 110 Query: 141 HFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQ 200 G + R + +G+ VDQ+ ++ +K NP RR I WNP +L MAL PC Q Sbjct: 111 -LGKKNRSL----NGEKVDQVDYLLHQLKNNPSSRRHITMLWNPDELDAMALTPCVYETQ 165 Query: 201 FYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLN 260 +YV + +L ++ RS DM LG PFN+ Y +L MIA +TG + G++I +GD H+Y Sbjct: 166 WYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNIGDCHVYTR 225 Query: 261 HIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 HI+ LKIQ++RE P+L I +V+ DF +DF++ Y + E+AV Sbjct: 226 HIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGDKLLFEVAV 278 >5JP9-A nrPDB Length = 325 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 30/104 (28%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Query: 157 GVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLM--ALPPCHALCQFYVVNSELSCQLYQ 214 GV+Q + V+ T+ +PD +R ++ ++PR+L + C QF + + L Y Sbjct: 111 GVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYM 170 Query: 215 RSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIY 258 R+ D G ++ S+ L A GL G + H +G HIY Sbjct: 171 RANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIY 214 >1B5E-A nrPDB Length = 246 Score = 34.7 bits (78), Expect = 0.052, Method: Compositional matrix adjust. Identities = 46/228 (20%), Positives = 80/228 (35%), Gaps = 48/228 (21%) Query: 49 DRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKI 108 D+TG T+ + G A + + F + + EL W+ S K++ + KI Sbjct: 27 DKTGVKTIEIIG--ASFVADEPFIFGALNDEY---IQRELEWYKSKSLFVKDIPGETPKI 81 Query: 109 WDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTI 168 W S +G++ YG+ + +S Q + + Sbjct: 82 WQQVAS------------SKGEINSNYGW-------------AIWSEDNYAQYDMCLAEL 116 Query: 169 KTNPDDRRIIMCAWNPR-----DLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGV 223 NPD RR IM P + M+ C Q+ + + +++ + RS D+ G Sbjct: 117 GQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGF 176 Query: 224 PFNIASYALLTYMIAHITG----------LKPGDFIHTLGDAHIYLNH 261 YA Y++ + K G I +G H+Y H Sbjct: 177 R---NDYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRH 221 >3AU7-A nrPDB Length = 402 Score = 33.9 bits (76), Expect = 0.094, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 155 GQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQF--YVVNSELSCQL 212 G+ V+ L + ++++KT P DRR+I + D+ L+ H L + Y + ++ + Sbjct: 238 GESVEALYKAMESVKTEPVDRRMIFVTNHATDMHLIGEEEVHRLENYRSYRLRGRVTLEP 297 Query: 213 YQRSG 217 Y G Sbjct: 298 YDIEG 302 >3AMU-A nrPDB Length = 440 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 27/122 (22%), Positives = 51/122 (41%), Gaps = 10/122 (8%) Query: 155 GQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQF--YVVNSELSCQL 212 G+ V+ L + ++++KT P DRR+I + D+ L+ H L + Y + ++ + Sbjct: 238 GESVEALYKAMESVKTEPVDRRMIFVTNHATDMHLIGEEEVHRLENYRSYRLRGRVTLEP 297 Query: 213 YQRSG-------DMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPL 265 Y G D G A++ I L+ GD + G ++E + Sbjct: 298 YDIEGGHVFFEIDTKFG-SVKCAAFEPTKQFRNVIRLLRKGDVVEVYGSMKKDTINLEKI 356 Query: 266 KI 267 +I Sbjct: 357 QI 358 >1ZCZ-A nrPDB Length = 464 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Query: 99 KELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQ 138 +EL KG +IW ++G+ FL S G E D+ + GF+ Sbjct: 31 RELHEKGWEIWASSGTAKFLKSNGI---EANDVSTITGFE 67 >2ZB3-A nrPDB Length = 353 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 23/44 (52%) Query: 64 RYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVK 107 R R+ F +L K F G+L+ WF +G KE +KG++ Sbjct: 282 RNITRERFTVLNYKDKFEPGILQLSQWFKEGKLKVKETMAKGLE 325 >4AZ4-A nrPDB Length = 186 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 20/72 (27%) Query: 222 GVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRI 281 G PF + + LL I H + H +G ++++++ PLK Q RI Sbjct: 115 GKPFELEADGLLAICIQH-------EMDHLVG--KLFMDYLSPLKQQ-----------RI 154 Query: 282 LRKVEKIDDFKA 293 +KVEK+D KA Sbjct: 155 RQKVEKLDRLKA 166 >5OVR-A nrPDB Length = 305 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 27/51 (52%) Query: 59 FGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIW 109 +G + + + + P+++T FW+ V +E I TN +E++ K + W Sbjct: 104 YGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYW 154 >5LK8-B nrPDB Length = 261 Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 63 ARYSLRDEFPLLTTKRVFWKGVLEEL 88 A + DE+P+LT + +FWK V E+ Sbjct: 42 ASSEVSDEYPMLTDRWLFWKSVKWEV 67 >5K8K-A nrPDB Length = 256 Score = 27.3 bits (59), Expect = 9.3, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 26/56 (46%) Query: 80 FWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVY 135 FW G E+ + K +S +GV+ + +G+RDFL FS L P Y Sbjct: 46 FWIGDDEQSALIQQVKDLIKFVSDQGVQCYFQHGNRDFLIGERFSKETGAQLLPDY 101 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4GYH-A nrPDB 560 e-160 4EIN-A nrPDB 541 e-154 4DP3-A nrPDB 506 e-144 3DGA-C nrPDB 496 e-141 5BY6-A nrPDB 492 e-140 5T0L-A nrPDB 487 e-138 4ECK-A nrPDB 487 e-138 5H3A-A nrPDB 486 e-138 4IQB-A nrPDB 484 e-137 3K2H-A nrPDB 478 e-135 3IRM-A nrPDB 474 e-134 1QZF-A nrPDB 472 e-134 4XSC-A nrPDB 470 e-133 1CI7-A nrPDB 468 e-132 2AAZ-A nrPDB 459 e-130 3KGB-A nrPDB 443 e-125 3IX6-A nrPDB 441 e-124 6AUJ-A nrPDB 433 e-122 6QXS-A nrPDB 428 e-120 4FOG-A nrPDB 423 e-119 4F2V-A nrPDB 414 e-116 4H0U-A nrPDB 414 e-116 1TSX-A nrPDB 412 e-115 4DQ1-A nrPDB 409 e-115 1TIS-A nrPDB 371 e-103 3V8H-A nrPDB 366 e-102 1BSF-A nrPDB 341 2e-94 5JP9-A nrPDB 136 1e-32 Sequences not found previously or not previously below threshold: 1B5E-A nrPDB 67 7e-12 1ZCZ-A nrPDB 30 1.1 6ECA-A nrPDB 30 1.3 1XDN-A nrPDB 29 2.4 5XXB-n nrPDB 28 7.0 >4GYH-A nrPDB Length = 318 Score = 560 bits (1443), Expect = e-160, Method: Composition-based stats. Identities = 313/313 (100%), Positives = 313/313 (100%) Query: 1 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG Sbjct: 1 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60 Query: 61 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS Sbjct: 61 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120 Query: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC Sbjct: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180 Query: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI Sbjct: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240 Query: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG Sbjct: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300 Query: 301 YNPHPTIKMEMAV 313 YNPHPTIKMEMAV Sbjct: 301 YNPHPTIKMEMAV 313 >4EIN-A nrPDB Length = 307 Score = 541 bits (1394), Expect = e-154, Method: Composition-based stats. Identities = 278/313 (88%), Positives = 292/313 (93%), Gaps = 6/313 (1%) Query: 1 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60 M V GSEL AQ+ AE P HGELQYL Q++HILRCG +K+DRTGTGTLSVFG Sbjct: 1 MLVVGSELQ-----SDAQQLSAEA-PRHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFG 54 Query: 61 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGV+IWDANGSRDFLDS Sbjct: 55 MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDS 114 Query: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180 LGFS R+EGDLGPVYGFQWRHFGAEY+DM+SDYSGQGVDQLQ+VIDTIKTNPDDRRIIMC Sbjct: 115 LGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMC 174 Query: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240 AWNP+DLPLMALPPCHALCQFYVVN ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI Sbjct: 175 AWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 234 Query: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300 TGL+PGDF+HTLGDAHIYLNHIEPLKIQLQREPRPFPKL+ILRKVE IDDFK EDFQIEG Sbjct: 235 TGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEG 294 Query: 301 YNPHPTIKMEMAV 313 YNPHPTIKMEMAV Sbjct: 295 YNPHPTIKMEMAV 307 >4DP3-A nrPDB Length = 608 Score = 506 bits (1303), Expect = e-144, Method: Composition-based stats. Identities = 161/300 (53%), Positives = 210/300 (70%) Query: 14 PPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPL 73 P Q ++ H E QYL I I+ G ++ DRTG G LS FG ++ L FPL Sbjct: 309 PNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPL 368 Query: 74 LTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGP 133 LTTK++F +G++EELLWFI+G TN L +K V+IW+ANG+R+FLD+ RE DLGP Sbjct: 369 LTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGP 428 Query: 134 VYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALP 193 +YGFQWRHFGAEY +M +Y +GVDQL+ +I+ IK +P RRI++CAWN +DL MALP Sbjct: 429 IYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALP 488 Query: 194 PCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLG 253 PCH LCQFYV + +LSC +YQRS D+GLGVPFNIASY++ T+MIA + L+P FIH LG Sbjct: 489 PCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLG 548 Query: 254 DAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 +AH+Y NHI+ LKIQL R P PFP L++ ++ I+DF DF I+ Y H I M+MA Sbjct: 549 NAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMAA 608 >3DGA-C nrPDB Length = 328 Score = 496 bits (1277), Expect = e-141, Method: Composition-based stats. Identities = 161/300 (53%), Positives = 210/300 (70%) Query: 14 PPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPL 73 P Q ++ H E QYL I I+ G ++ DRTG G LS FG ++ L FPL Sbjct: 29 PNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPL 88 Query: 74 LTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGP 133 LTTK++F +G++EELLWFI+G TN L +K V+IW+ANG+R+FLD+ RE DLGP Sbjct: 89 LTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGP 148 Query: 134 VYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALP 193 +YGFQWRHFGAEY +M +Y +GVDQL+ +I+ IK +P RRI++CAWN +DL MALP Sbjct: 149 IYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALP 208 Query: 194 PCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLG 253 PCH LCQFYV + +LSC +YQRS D+GLGVPFNIASY++ T+MIA + L+P FIH LG Sbjct: 209 PCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLG 268 Query: 254 DAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 +AH+Y NHI+ LKIQL R P PFP L++ ++ I+DF DF I+ Y H I M+MA Sbjct: 269 NAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMAA 328 >5BY6-A nrPDB Length = 307 Score = 492 bits (1267), Expect = e-140, Method: Composition-based stats. Identities = 196/299 (65%), Positives = 229/299 (76%), Gaps = 1/299 (0%) Query: 16 AAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLL 74 + EL YL Q++ I+ GVRK+DRTG GTLS FG Q+RY LRD+ FPLL Sbjct: 9 DTNSTSQDDYVNQEELNYLNQLKDIIDHGVRKNDRTGIGTLSTFGTQSRYCLRDDIFPLL 68 Query: 75 TTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPV 134 TTKRVFW+GV+EELLWFI GSTNAK+LS K V IWD N SR+FLDS G EEGDLGPV Sbjct: 69 TTKRVFWRGVVEELLWFISGSTNAKQLSEKNVNIWDGNSSREFLDSRGLYNYEEGDLGPV 128 Query: 135 YGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPP 194 YGFQWRHFG Y M +DY G+G DQLQ+ I I+ P+ RRIIM AWNP DL +ALPP Sbjct: 129 YGFQWRHFGCPYSSMTADYKGKGYDQLQQCIKMIREEPESRRIIMTAWNPCDLEKVALPP 188 Query: 195 CHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGD 254 CH QFYV + ELSCQ+YQRS DMGLGVPFNIASY+LLT MIAHIT LKPG FIHT+GD Sbjct: 189 CHCFVQFYVADGELSCQMYQRSADMGLGVPFNIASYSLLTRMIAHITSLKPGFFIHTIGD 248 Query: 255 AHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 AH+YL H++ LK+Q++R+PRPFPKL+ILR VE IDDF+AEDF++ Y P+P I M MAV Sbjct: 249 AHVYLTHVDALKVQMERKPRPFPKLKILRNVENIDDFRAEDFELINYKPYPKISMPMAV 307 >5T0L-A nrPDB Length = 566 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 187/289 (64%), Positives = 220/289 (76%), Gaps = 3/289 (1%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL I I+ G DDRTG G +S FG RYSL FPLLTTKRVFWKGVLEE Sbjct: 278 HEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEE 337 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFI+G TNA LS KGVKIWD N +R+FLDS RE GD+GP YGFQWRHFGA Y+ Sbjct: 338 LLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYK 397 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVN-S 206 DM +DY+GQGVDQL+ VI ++TNP DRR++M AWNP L MALPPCH LCQFYV + Sbjct: 398 DMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQK 457 Query: 207 ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 ELSC +YQRS D+GLGVPFNIASY+LLT M+AH+ LKP +FIH +G+ H+Y NH+E LK Sbjct: 458 ELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALK 517 Query: 267 IQLQREPRPFPKLRILRK--VEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 QL+REPRPFP + IL K +++IDDF AEDF++ GY PH I+MEMAV Sbjct: 518 EQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 566 >4ECK-A nrPDB Length = 610 Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats. Identities = 187/289 (64%), Positives = 220/289 (76%), Gaps = 3/289 (1%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL I I+ G DDRTG G +S FG RYSL FPLLTTKRVFWKGVLEE Sbjct: 322 HEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEE 381 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFI+G TNA LS KGVKIWD N +R+FLDS RE GD+GP YGFQWRHFGA Y+ Sbjct: 382 LLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYK 441 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVN-S 206 DM +DY+GQGVDQL+ VI ++TNP DRR++M AWNP L MALPPCH LCQFYV + Sbjct: 442 DMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQK 501 Query: 207 ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 ELSC +YQRS D+GLGVPFNIASY+LLT M+AH+ LKP +FIH +G+ H+Y NH+E LK Sbjct: 502 ELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALK 561 Query: 267 IQLQREPRPFPKLRILRK--VEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 QL+REPRPFP + IL K +++IDDF AEDF++ GY PH I+MEMAV Sbjct: 562 EQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 610 >5H3A-A nrPDB Length = 283 Score = 486 bits (1250), Expect = e-138, Method: Composition-based stats. Identities = 203/283 (71%), Positives = 237/283 (83%) Query: 27 PHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLE 86 PH ELQYL Q++ IL G + DRTG GTLS+FGMQARYSLRD FPLLTTKRVFW+GV++ Sbjct: 1 PHEELQYLRQLREILCRGSDRLDRTGIGTLSLFGMQARYSLRDHFPLLTTKRVFWRGVVQ 60 Query: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146 ELLWF+KGST+++ELS GVKIWD NGSR+FL G + R EGDLGPVYGFQWRHFGA Y Sbjct: 61 ELLWFLKGSTDSRELSRTGVKIWDKNGSREFLAGRGLAHRREGDLGPVYGFQWRHFGAAY 120 Query: 147 RDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNS 206 D ++DY+GQG DQL ++D IK NP DRRIIMCAWNP DL LMALPPCH LCQFYV + Sbjct: 121 VDADADYTGQGFDQLSYIVDLIKNNPHDRRIIMCAWNPADLSLMALPPCHLLCQFYVADG 180 Query: 207 ELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 ELSCQLYQRSGDMGLGVPFNIASY+LLTYM+AH+TGL+PG+FIHTLGDAHIY HIEPL+ Sbjct: 181 ELSCQLYQRSGDMGLGVPFNIASYSLLTYMLAHVTGLRPGEFIHTLGDAHIYKTHIEPLR 240 Query: 267 IQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKM 309 +QL R PRPFP+L ILR V +++F +DF++ Y PHPTI+M Sbjct: 241 LQLTRTPRPFPRLEILRSVSSMEEFTPDDFRLVDYCPHPTIRM 283 >4IQB-A nrPDB Length = 315 Score = 484 bits (1245), Expect = e-137, Method: Composition-based stats. Identities = 198/315 (62%), Positives = 231/315 (73%), Gaps = 2/315 (0%) Query: 1 MPVAGSELPRRPLPPAA-QERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVF 59 M V E P + + E +YL Q++ ILR G R+DDRTGTGT+S+F Sbjct: 1 MEVMNKENIIADAPSDVVKTVQQQVHLNQDEYKYLKQVEQILREGTRRDDRTGTGTISIF 60 Query: 60 GMQARYSLRDE-FPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFL 118 GMQ++Y LR+ PLLTTKRV+WKGVLEELLWFI GST+ K L K VKIW+ NG R FL Sbjct: 61 GMQSKYCLRNGTIPLLTTKRVYWKGVLEELLWFISGSTDGKLLMEKNVKIWEKNGDRAFL 120 Query: 119 DSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRII 178 D+LGF++REEGDLGPVYGFQWRHFGA+Y D +DYSGQGVDQL VI IK PD RRII Sbjct: 121 DNLGFTSREEGDLGPVYGFQWRHFGAKYVDCHTDYSGQGVDQLAEVIRQIKEQPDSRRII 180 Query: 179 MCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIA 238 M AWNP DL M LPPCH +CQFYV N ELSCQLYQRSGDMGLGVPFN+ASY LLT+MIA Sbjct: 181 MSAWNPSDLGQMVLPPCHTMCQFYVDNGELSCQLYQRSGDMGLGVPFNLASYGLLTHMIA 240 Query: 239 HITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQI 298 + GLKPG +HTLGDAH+Y NH++ LKIQL REP FPK+R R V IDDF ++ + Sbjct: 241 KVCGLKPGTLVHTLGDAHVYSNHVDALKIQLDREPYAFPKIRFTRDVASIDDFTSDMIAL 300 Query: 299 EGYNPHPTIKMEMAV 313 + Y HP I M+MAV Sbjct: 301 DDYKCHPKIPMDMAV 315 >3K2H-A nrPDB Length = 511 Score = 478 bits (1231), Expect = e-135, Method: Composition-based stats. Identities = 160/286 (55%), Positives = 209/286 (73%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL + +L GV K +RTGT S FG Q R+ L FPLLTTK+V + ++EE Sbjct: 226 HEEFQYLDILADVLSHGVLKPNRTGTDAYSKFGYQMRFDLSRSFPLLTTKKVALRSIIEE 285 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 LLWFIKGSTN +L +K V+IW+ NG RDFLD GF+ REE DLGP+YGFQWRHFGAEY Sbjct: 286 LLWFIKGSTNGNDLLAKNVRIWELNGRRDFLDKNGFTDREEHDLGPIYGFQWRHFGAEYL 345 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSE 207 DM +DY+G+G+DQL +I+ IKTNP+DRR+I+C+WN DL MALPPCH QFYV +++ Sbjct: 346 DMHADYTGKGIDQLAEIINRIKTNPNDRRLIVCSWNVSDLKKMALPPCHCFFQFYVSDNK 405 Query: 208 LSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKI 267 LSC ++QRS D+GLGVPFNIASY++LT M+A + GL G+F+H L DAHIY++H++ + Sbjct: 406 LSCMMHQRSCDLGLGVPFNIASYSILTAMVAQVCGLGLGEFVHNLADAHIYVDHVDAVTT 465 Query: 268 QLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 Q+ R P PFP+LR+ + I+DF +D +E Y HP I M M+ Sbjct: 466 QIARIPHPFPRLRLNPDIRNIEDFTIDDIVVEDYVSHPPIPMAMSA 511 >3IRM-A nrPDB Length = 521 Score = 474 bits (1221), Expect = e-134, Method: Composition-based stats. Identities = 184/320 (57%), Positives = 224/320 (70%), Gaps = 10/320 (3%) Query: 4 AGSELPRRPLPPAAQERDAEPRPPH---------GELQYLGQIQHILRCGVRKDDRTGTG 54 AG E R + + + E QYL + I+R G K DRTG G Sbjct: 202 AGIEWQRETISEELTSANGNETKYYFEKLIPRNREEEQYLSLVDRIIREGNVKHDRTGVG 261 Query: 55 TLSVFGMQARYSLRDE-FPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANG 113 TLS+FG Q R+SLR+ PLLTTKRVFW+GV EELLWF++G T AK+LS KGV IWD NG Sbjct: 262 TLSIFGAQMRFSLRNNRLPLLTTKRVFWRGVCEELLWFLRGETYAKKLSDKGVHIWDDNG 321 Query: 114 SRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPD 173 SR FLDS G + EE DLGPVYGFQWRHFGA Y +++Y GQGVDQ++ +++T+KTNPD Sbjct: 322 SRAFLDSRGLTEYEEMDLGPVYGFQWRHFGAAYTHHDANYDGQGVDQIKAIVETLKTNPD 381 Query: 174 DRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALL 233 DRR++ AWNP LP MALPPCH L QFYV N ELSC LYQRS DMGLGVPFNIASYALL Sbjct: 382 DRRMLFTAWNPSALPRMALPPCHLLAQFYVSNGELSCMLYQRSCDMGLGVPFNIASYALL 441 Query: 234 TYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKA 293 T +IA TGL+PG+ +HTLGDAH+Y NH+EP QL+R PR FP L R+ E ++D++ Sbjct: 442 TILIAKATGLRPGELVHTLGDAHVYSNHVEPCNEQLKRVPRAFPYLVFRREREFLEDYEE 501 Query: 294 EDFQIEGYNPHPTIKMEMAV 313 D ++ Y P+P I M+MAV Sbjct: 502 GDMEVIDYAPYPPISMKMAV 521 >1QZF-A nrPDB Length = 521 Score = 472 bits (1215), Expect = e-134, Method: Composition-based stats. Identities = 162/287 (56%), Positives = 205/287 (71%), Gaps = 1/287 (0%) Query: 28 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEE 87 H E QYL + +L G +++RTG T S+FG R+ +R+ FPLLTTK+V + + EE Sbjct: 235 HYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEE 294 Query: 88 LLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYR 147 L+WFIKG TN L K V IW NGS+++L+ +G REE DLGP+YGFQWRH+ EY+ Sbjct: 295 LIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYK 354 Query: 148 DMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSE 207 M DY+G GVDQL ++I+T+K NP DRR I+ AWNP L MALPPCH L Q+YV N Sbjct: 355 TMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDN 414 Query: 208 -LSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLK 266 LSC LYQRS D+GLG PFNIASYA+LT M+A + G +PG+ +GDAHIY NH+ LK Sbjct: 415 CLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLK 474 Query: 267 IQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 QL R PRPFP+L+ RKVE I+DFK ED ++ GY P+PTIKM+MAV Sbjct: 475 EQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 521 >4XSC-A nrPDB Length = 311 Score = 470 bits (1211), Expect = e-133, Method: Composition-based stats. Identities = 199/279 (71%), Positives = 238/279 (85%) Query: 29 GELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEEL 88 GELQYL Q+ ILR GVRK DRTG GTLS+FGMQARY+LR+EFPLLTTKRVFW+ V+EEL Sbjct: 33 GELQYLKQVDDILRYGVRKRDRTGIGTLSLFGMQARYNLRNEFPLLTTKRVFWRAVVEEL 92 Query: 89 LWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRD 148 LWFI+GST++KEL++K + IWD GS FL+ GF R GDLGP+YGFQWRHFGAEY+D Sbjct: 93 LWFIRGSTDSKELAAKDIHIWDIYGSSKFLNRNGFHKRHTGDLGPIYGFQWRHFGAEYKD 152 Query: 149 MESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSEL 208 +S+Y QG+DQLQ VIDTIKTNP+ RR+I+ +WNP+D+PLM LPPCH LCQFYV N EL Sbjct: 153 CQSNYLQQGIDQLQTVIDTIKTNPESRRMIISSWNPKDIPLMVLPPCHTLCQFYVANGEL 212 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQ 268 SCQ+YQRSGDMGLGVPFNIA YALLTY++AH+TGLK GD IHT+GDAHIYLNHI+ LK+Q Sbjct: 213 SCQVYQRSGDMGLGVPFNIAGYALLTYIVAHVTGLKTGDLIHTMGDAHIYLNHIDALKVQ 272 Query: 269 LQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTI 307 L R P+PFP L+I+R V I+DFK +DFQ++GYNPHP + Sbjct: 273 LARSPKPFPCLKIIRNVTDINDFKWDDFQLDGYNPHPPL 311 >1CI7-A nrPDB Length = 297 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 180/293 (61%), Positives = 223/293 (76%), Gaps = 8/293 (2%) Query: 29 GELQYLGQIQHILRCGVRKDDRTGTGTLSVFGM-QARYSLRDE-FPLLTTKRVFWKGVLE 86 E QYL +Q+I+ G + DRTGTGTLSVF ++SLR++ FPLLTTKRVF +GV+E Sbjct: 5 EEQQYLNLVQYIINHGEDRPDRTGTGTLSVFAPSPLKFSLRNKTFPLLTTKRVFIRGVIE 64 Query: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEY 146 ELLWFI+G T++ +L K + IWDANGSR++LDS+G + R+EGDLGP+YGFQWRHFGAEY Sbjct: 65 ELLWFIRGETDSLKLREKNIHIWDANGSREYLDSIGLTKRQEGDLGPIYGFQWRHFGAEY 124 Query: 147 RDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYV--- 203 D +++Y GQGVDQL +I I+T+P DRR+I+ AWNP DL MALPPCH CQFYV Sbjct: 125 IDCKTNYIGQGVDQLANIIQKIRTSPYDRRLILSAWNPADLEKMALPPCHMFCQFYVHIP 184 Query: 204 ---VNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLN 260 ELSCQLYQRS DMGLGVPFNIASYALLT MIAH+ L PGDFIH +GD HIY + Sbjct: 185 SNNHRPELSCQLYQRSCDMGLGVPFNIASYALLTCMIAHVCDLDPGDFIHVMGDCHIYKD 244 Query: 261 HIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 HIE L+ QL R PRPFP L + R + I+DF +DF I+ Y+P+ TIKM+M++ Sbjct: 245 HIEALQQQLTRSPRPFPTLSLNRSITDIEDFTLDDFNIQNYHPYETIKMKMSI 297 >2AAZ-A nrPDB Length = 317 Score = 459 bits (1182), Expect = e-130, Method: Composition-based stats. Identities = 187/312 (59%), Positives = 226/312 (72%), Gaps = 14/312 (4%) Query: 16 AAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQA-RYSLRDE-FPL 73 QE++ P H E QYL I+ I+ G + DRTGTGT+++F + R+SL D PL Sbjct: 6 DDQEKNQRSNPDHEEYQYLDLIRRIINVGEVRPDRTGTGTVALFAPPSFRFSLADNTLPL 65 Query: 74 LTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGP 133 LTTKRVF +GV+ ELLWF+ G T+AK LSS+GV IWD NGS++FL+ +G R EGDLGP Sbjct: 66 LTTKRVFLRGVIAELLWFVSGCTDAKMLSSQGVGIWDGNGSKEFLEKVGLGHRREGDLGP 125 Query: 134 VYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALP 193 VYGFQWRHFGAEY D + DY G+GVDQLQRVIDTIK NP DRRII+ AWNP+DLPLMALP Sbjct: 126 VYGFQWRHFGAEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPKDLPLMALP 185 Query: 194 PCHALCQFYV---------VNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLK 244 PCH CQF+V +LSC +YQRS D+GLGVPFNIASYALLT+MIA IT + Sbjct: 186 PCHMFCQFFVSLPPADSPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHMIALITDTE 245 Query: 245 PGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVE---KIDDFKAEDFQIEGY 301 P +FI +GDAH+Y +H+EPLK QL+REPR FPKL+ R E ID FK EDF +EGY Sbjct: 246 PHEFILQMGDAHVYRDHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKVEDFVVEGY 305 Query: 302 NPHPTIKMEMAV 313 P I M+M+ Sbjct: 306 KPWGKIDMKMSA 317 >3KGB-A nrPDB Length = 294 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 173/291 (59%), Positives = 221/291 (75%), Gaps = 4/291 (1%) Query: 26 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDE-FPLLTTKRVFWKGV 84 P H E QYL ++HIL G R+ DRTGTGTLSVFG R+SL D FPLLTT+RVF++GV Sbjct: 5 PRHPEHQYLDLVKHILENGARRMDRTGTGTLSVFGATMRFSLEDNTFPLLTTRRVFYRGV 64 Query: 85 LEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGA 144 +EELL+F++G T++K L KGV+IW+ NG++ FL S+G REEGDLGP+YGFQWRHFGA Sbjct: 65 VEELLFFLRGETDSKVLEKKGVRIWEKNGAKQFLQSVGI-DREEGDLGPIYGFQWRHFGA 123 Query: 145 EYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVV 204 Y S Y G+GVDQ+ I I+ NP RRI++ AWNP DL MALPPCH L QF V Sbjct: 124 RYETSASSYEGKGVDQIASAIAAIRANPASRRIVVSAWNPTDLGSMALPPCHVLFQFNVT 183 Query: 205 NSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEP 264 + +LSC +YQRSGDMGLGVPFNIASY+LLT ++AH+TGL+PG+F+H LGDAH+YL+H++ Sbjct: 184 DGKLSCAMYQRSGDMGLGVPFNIASYSLLTILVAHLTGLQPGEFVHFLGDAHVYLDHVDS 243 Query: 265 LKIQLQREPRPFPKLRILRKVEKI--DDFKAEDFQIEGYNPHPTIKMEMAV 313 L+ Q+QR PR FPKL + K + + F+ EDF++ GY+PHP IKM M+ Sbjct: 244 LRQQIQRPPRAFPKLFVSPKGPRTEPEHFQYEDFELVGYDPHPAIKMNMSA 294 >3IX6-A nrPDB Length = 360 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 151/311 (48%), Positives = 191/311 (61%), Gaps = 20/311 (6%) Query: 3 VAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQ 62 + + P +A G YL +QH+L GV +DDRTGTGT SVFG Q Sbjct: 70 IQADQTPEDLDMEDNDIIEAHREQIGGMRTYLDLLQHVLDHGVDRDDRTGTGTRSVFGYQ 129 Query: 63 ARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLG 122 R+ L + FP+LTTK++ + ++ ELLWF+KG TN L GV IWD Sbjct: 130 MRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGDTNIAYLKENGVTIWDEWAD-------- 181 Query: 123 FSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAW 182 E GDLGPVYG+QWR + A G+ +DQ+ ++ + TNP RR+I+ AW Sbjct: 182 ----ENGDLGPVYGYQWRSWPAP--------DGRHIDQIANLLKMLHTNPQSRRLIVSAW 229 Query: 183 NPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITG 242 NP + MALPPCH L QFYV N LSCQLYQRS D+ LGVPFNIASYALLT MIA +TG Sbjct: 230 NPALVDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTG 289 Query: 243 LKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYN 302 LKPG+FIHTLGDAHIY NH E ++QL R P+ P + I V+ + F+ EDF+++GY Sbjct: 290 LKPGEFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYE 349 Query: 303 PHPTIKMEMAV 313 PTIK +AV Sbjct: 350 ADPTIKAPIAV 360 >6AUJ-A nrPDB Length = 272 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 145/284 (51%), Positives = 181/284 (63%), Gaps = 20/284 (7%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 YL +Q IL G K DRTGTGT S+FG Q RY L FPL+TTK+V K ++ ELL Sbjct: 9 MQNYLHLLQDILDNGSDKTDRTGTGTRSLFGYQLRYDLSKGFPLVTTKKVHLKSIIYELL 68 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDM 149 WF+KG TN K L GV IWD E GDLGPVYG QWR + Sbjct: 69 WFLKGDTNIKYLKDNGVSIWDEWAD------------ENGDLGPVYGAQWRSW------- 109 Query: 150 ESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELS 209 + VDQ+ VID IK NPD RR+I+ AWN ++P MAL PCHA+ QFYV + +LS Sbjct: 110 -RGADNKVVDQISEVIDQIKKNPDSRRLIVSAWNVAEIPNMALAPCHAMFQFYVADGKLS 168 Query: 210 CQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQL 269 QLYQRS D+ LGVPFNIASYALL M+A +TGL+ GD++H+ GD HIY NH E + QL Sbjct: 169 LQLYQRSADVFLGVPFNIASYALLLMMVAQVTGLQVGDYVHSFGDVHIYNNHFEQVNRQL 228 Query: 270 QREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 R+P+P P +++ V+ I DFK EDF++ Y+PHP IK +A+ Sbjct: 229 SRDPKPLPVMKLNPDVKDIFDFKFEDFELLNYDPHPGIKAPVAI 272 >6QXS-A nrPDB Length = 315 Score = 428 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 152/322 (47%), Positives = 191/322 (59%), Gaps = 46/322 (14%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 E YL + IL G K+DRTGTGT S+FG Q R+ L FPLLTTKRV + + ELL Sbjct: 2 EEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKRVPFGLIKSELL 61 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFL--------DSLGFSTR--------------- 126 WF+KG TN + L + IWD ++ D F R Sbjct: 62 WFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDMTDFGHRVLQDPAFAEQYKEEH 121 Query: 127 ---------------EEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTN 171 + G+LG +YG QWRH+ + G +DQL VI+ IKTN Sbjct: 122 QKFCDAILNDAEFAEKYGELGNIYGAQWRHWETK--------DGSFIDQLANVIEMIKTN 173 Query: 172 PDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYA 231 PD RR+I+ AWNP D+P MALPPCH + QFYV +LSCQLYQRS D+ LGVPFNIASYA Sbjct: 174 PDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVNEGKLSCQLYQRSADVFLGVPFNIASYA 233 Query: 232 LLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDF 291 LLT++IAH TGL+ G+F+HTLGDAH+Y NH+E ++ QL RE R FP L + + DF Sbjct: 234 LLTHLIAHETGLEVGEFVHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDF 293 Query: 292 KAEDFQIEGYNPHPTIKMEMAV 313 ED ++EGY+PHPTIK +AV Sbjct: 294 DMEDIKVEGYDPHPTIKAPIAV 315 >4FOG-A nrPDB Length = 263 Score = 423 bits (1087), Expect = e-119, Method: Composition-based stats. Identities = 141/284 (49%), Positives = 182/284 (64%), Gaps = 21/284 (7%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 Y ++ +L G K DRTGTGT S+FG Q RY L FPLLTTK+V +K V ELL Sbjct: 1 MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDM 149 WF++G +N L GV IWD S + G+LGP+YG QWR + A Sbjct: 61 WFLRGDSNIGWLHEHGVTIWDEWAS------------DTGELGPIYGVQWRSWPAP---- 104 Query: 150 ESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELS 209 SG+ +DQ+ +D ++T+PD RRII+ AWN ++ MALPPCHA QFYV + LS Sbjct: 105 ----SGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS 160 Query: 210 CQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQL 269 CQLYQRS D+ LGVPFNIASYALLT+M+A GL G+FI T GD HIY NH+E +++QL Sbjct: 161 CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQL 220 Query: 270 QREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 REPRP+PKL +L + I ++ ED ++ Y+PHP IK +AV Sbjct: 221 SREPRPYPKL-LLADRDSIFEYTYEDIVVKNYDPHPAIKAPVAV 263 >4F2V-A nrPDB Length = 272 Score = 414 bits (1065), Expect = e-116, Method: Composition-based stats. Identities = 135/284 (47%), Positives = 178/284 (62%), Gaps = 20/284 (7%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 QYL +Q +L G +K+DRTGTGTLS+FG Q R++L+D FPL+TTKR + ++ LL Sbjct: 1 MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHLLL 60 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDM 149 WF++G TN L V I D E GDLGPV+G QWR + Sbjct: 61 WFLQGDTNIAYLHENNVTILDEWAD------------ENGDLGPVHGKQWRAWPTP---- 104 Query: 150 ESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELS 209 G+ +DQ+ V++ +K +PD RRII+ AWN +L MA P HA QFYV + +LS Sbjct: 105 ----DGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMANAPSHAFFQFYVADGKLS 160 Query: 210 CQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQL 269 CQLY RS D+ L +PF IAS ALL +M+A L+ GDF+ T GD H+Y NH++ +QL Sbjct: 161 CQLYARSEDVFLSLPFAIASGALLVHMMAQQCDLEVGDFVMTGGDTHLYSNHMDQTHLQL 220 Query: 270 QREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 REPRP PKL I RK E I D++ EDF+IEGY+PHP IK +A+ Sbjct: 221 SREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI 264 >4H0U-A nrPDB Length = 266 Score = 414 bits (1065), Expect = e-116, Method: Composition-based stats. Identities = 133/282 (47%), Positives = 176/282 (62%), Gaps = 21/282 (7%) Query: 32 QYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWF 91 Y ++ I G KDDRTGTGT S+FG Q R+ L + FPLLTTK+V + V+ ELLWF Sbjct: 6 PYEDLLRKIAEEGSHKDDRTGTGTTSLFGQQIRFDLNEGFPLLTTKKVHFHSVVGELLWF 65 Query: 92 IKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMES 151 ++G +N K L ++IW+ E+G+LGPVYG QWR + Sbjct: 66 LQGDSNVKWLQDNNIRIWNEWAD------------EDGELGPVYGVQWRSWPTP------ 107 Query: 152 DYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQ 211 G+ +DQ+ ++T++ NPD RR I+ AWN +L MALPPCH L Q YV + +LSCQ Sbjct: 108 --DGRHIDQISGALETLRNNPDSRRNIVSAWNVSELENMALPPCHLLFQLYVADGKLSCQ 165 Query: 212 LYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQR 271 LYQRS DM LGVPFNIASYALLT+M A GL+ G+FI T GD HIY NH E + QL R Sbjct: 166 LYQRSADMFLGVPFNIASYALLTHMFAQQAGLEVGEFIWTGGDCHIYDNHKEQVAEQLSR 225 Query: 272 EPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 E RP+P L + K + ++ +D + GY+PHP I+ ++AV Sbjct: 226 EARPYPTLELN-KAASMFEYSFDDITVSGYDPHPLIRGKVAV 266 >1TSX-A nrPDB Length = 316 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 140/322 (43%), Positives = 180/322 (55%), Gaps = 46/322 (14%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 E YL + +L G K DRT TGT S+FG Q R+ L FPLLTTK+V + + ELL Sbjct: 3 EQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTKKVPFGLIKSELL 62 Query: 90 WFIKGSTNAKELSSKGVKIWDANGSRDFL--------DSLGFSTREE------------- 128 WF+ G TN + L IWD ++ D F R + Sbjct: 63 WFLHGDTNIRFLLQHRNHIWDEWAFEKWVKSDEYHGPDMTDFGHRSQKDPEFAAVYHEEM 122 Query: 129 -----------------GDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTN 171 GDLG VYG QWR + G +DQL VI+ IKT+ Sbjct: 123 AKFDDRVLHDDAFAAKYGDLGLVYGSQWRAWHTS--------KGDTIDQLGDVIEQIKTH 174 Query: 172 PDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYA 231 P R +I+ AWNP D+P MALPPCH L QFYV + +LS QLYQRS D+ LGVPFNIASYA Sbjct: 175 PYSRELIVSAWNPEDVPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYA 234 Query: 232 LLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDF 291 LLT+++AH GL+ G+FIHT GDAH+Y+NH++ +K QL R PRP P L++ I DF Sbjct: 235 LLTHLVAHECGLEVGEFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDF 294 Query: 292 KAEDFQIEGYNPHPTIKMEMAV 313 +D ++ Y+P+P IK +AV Sbjct: 295 DMKDIKLLNYDPYPAIKAPVAV 316 >4DQ1-A nrPDB Length = 321 Score = 409 bits (1051), Expect = e-115, Method: Composition-based stats. Identities = 141/319 (44%), Positives = 177/319 (55%), Gaps = 47/319 (14%) Query: 33 YLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFI 92 Y + +L G ++DRT TGT+S FG Q R+ L FPLLTTK+V +K V ELLWFI Sbjct: 12 YHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLLTTKKVSFKLVATELLWFI 71 Query: 93 KGSTNAKELSSKGVKIWDANGSRDFL--------DSLGFSTR------------------ 126 KG TN + L IW+ +++ D F R Sbjct: 72 KGDTNIQYLLKYNNNIWNEWAFENYIKSDEYNGPDMTDFGHRALSDPEFNEQYKEQMKQF 131 Query: 127 ------------EEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDD 174 + GDLG VYG QWR + D G DQL+ VI+ IK NPD Sbjct: 132 KQRILEDDTFAKQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDS 183 Query: 175 RRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLT 234 RR I+ AWNP ++ MALPPCH + QFYV + +LSCQLYQRS D+ LGVPFNIASYALLT Sbjct: 184 RRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLT 243 Query: 235 YMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAE 294 ++IA GL+ G+F+HT GDAHIY NHI+ ++ QL RE P L+I + I D E Sbjct: 244 HLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINSD-KSIFDINYE 302 Query: 295 DFQIEGYNPHPTIKMEMAV 313 D +I Y HP IK +AV Sbjct: 303 DLEIVDYESHPAIKAPIAV 321 >1TIS-A nrPDB Length = 286 Score = 371 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 127/303 (41%), Positives = 169/303 (55%), Gaps = 36/303 (11%) Query: 30 ELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELL 89 QY I+ I G DDRTGTGT+++FG + R+ L FP +TTK++ WK + EL+ Sbjct: 1 MKQYQDLIKDIFENGYETDDRTGTGTIALFGSKLRWDLTKGFPAVTTKKLAWKACIAELI 60 Query: 90 WFIKGSTNAKELS-------SKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHF 142 WF+ GSTN +L +G +WD N D G+LGP+YG QWR F Sbjct: 61 WFLSGSTNVNDLRLIQHDSLIQGKTVWDENYENQAKDL----GYHSGELGPIYGKQWRDF 116 Query: 143 GAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFY 202 G GVDQ+ VID IK P+DRR I+ AWNP +L MALPPCH QF Sbjct: 117 G-------------GVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFN 163 Query: 203 VVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHI 262 V N L Q YQRS D+ LG+PFNIASYA L +++A + L PGD I + G+ HIY+NH+ Sbjct: 164 VRNGYLDLQWYQRSVDVFLGLPFNIASYATLVHIVAKMCNLIPGDLIFSGGNTHIYMNHV 223 Query: 263 EPLKIQLQREPRPFPKLRI------------LRKVEKIDDFKAEDFQIEGYNPHPTIKME 310 E K L+REP+ +L I +++ + + +DF + Y HP IK + Sbjct: 224 EQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKLRPKDFVLNNYVSHPPIKGK 283 Query: 311 MAV 313 MAV Sbjct: 284 MAV 286 >3V8H-A nrPDB Length = 327 Score = 366 bits (939), Expect = e-102, Method: Composition-based stats. Identities = 112/326 (34%), Positives = 164/326 (50%), Gaps = 39/326 (11%) Query: 27 PHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLE 86 P QYL ++ IL G + +RTG T+ + G R+ L+ FP +TTK++ +K + Sbjct: 2 PGSMKQYLDLVRTILDTGTWQSNRTGIRTIGIPGAMLRFDLQQGFPAVTTKKLAFKSAIG 61 Query: 87 ELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHF-GAE 145 EL+ F++ + +A E + G K+WDAN + + R DLG VYG QWR + G + Sbjct: 62 ELVGFLRATRSAAEFRALGCKVWDANANENAQWLANPYRRGADDLGDVYGVQWRRWPGYK 121 Query: 146 YRDMESDYS-------------------------GQGVDQLQRVIDTIKTNPDDRRIIMC 180 D +D + +DQL+ +DTI +P RRI+ Sbjct: 122 VLDAHADAQIADATSRGFRIVARFEEGGADKVLLHKAIDQLRDCLDTIVRDPSSRRILFH 181 Query: 181 AWNPRDLPLMALPPCHALCQFY--VVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIA 238 WNP L +ALP CH L QF V E+S LY RS D+GLG PFN+A A L ++ Sbjct: 182 GWNPAVLDEIALPACHLLYQFLPNVERREISLCLYIRSNDVGLGTPFNLAEGAALLTLVG 241 Query: 239 HITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKV-----------EK 287 +TG P F + +GDAHIY N ++ LK QL+REP P+L + +V + Sbjct: 242 RLTGYSPRWFTYFIGDAHIYENQLDMLKQQLEREPFESPRLELAERVPDYAKTGKYEPQW 301 Query: 288 IDDFKAEDFQIEGYNPHPTIKMEMAV 313 ++ + DF + GY H + MAV Sbjct: 302 LERVEPSDFTLVGYRHHEPLSAPMAV 327 >1BSF-A nrPDB Length = 278 Score = 341 bits (876), Expect = 2e-94, Method: Composition-based stats. Identities = 107/295 (36%), Positives = 156/295 (52%), Gaps = 31/295 (10%) Query: 30 ELQYLGQIQHILRCGV----------RKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRV 79 + QY I+ I+ G+ D T TLSV Q R+ E P+LTTK+V Sbjct: 4 DKQYNSIIKDIINNGISDEEFDVRTKWDSDGTPAHTLSVISKQMRFD-NSEVPILTTKKV 62 Query: 80 FWKGVLEELLWFIK-GSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQ 138 WK ++ELLW + S + +L+ GV IWD +E+G +G YGFQ Sbjct: 63 AWKTAIKELLWIWQLKSNDVNDLNMMGVHIWDQW------------KQEDGTIGHAYGFQ 110 Query: 139 WRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHAL 198 G + R + +G+ VDQ+ ++ +K NP RR I WNP +L MAL PC Sbjct: 111 ---LGKKNRSL----NGEKVDQVDYLLHQLKNNPSSRRHITMLWNPDELDAMALTPCVYE 163 Query: 199 CQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIY 258 Q+YV + +L ++ RS DM LG PFN+ Y +L MIA +TG + G++I +GD H+Y Sbjct: 164 TQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNIGDCHVY 223 Query: 259 LNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 313 HI+ LKIQ++RE P+L I +V+ DF +DF++ Y + E+AV Sbjct: 224 TRHIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGDKLLFEVAV 278 >5JP9-A nrPDB Length = 325 Score = 136 bits (343), Expect = 1e-32, Method: Composition-based stats. Identities = 50/231 (21%), Positives = 83/231 (35%), Gaps = 28/231 (12%) Query: 33 YLGQIQHILRCGVRKDDRTGTGTLSVFGMQARY-SLRDEFPLLTTKRVFWKGVLEELLWF 91 YL Q++ I ++ G + G R + +R E LW+ Sbjct: 9 YLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWY 68 Query: 92 IKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQ-WRHFGAEYRDME 150 + GS + I + L G YG + +RH Sbjct: 69 LSGSDRLDFIQYYAPGIAAYSADGRTLR------------GTAYGPRIFRH--------- 107 Query: 151 SDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLM--ALPPCHALCQFYVVNSEL 208 GV+Q + V+ T+ +PD +R ++ ++PR+L + C QF + + L Sbjct: 108 ---PAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLL 164 Query: 209 SCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYL 259 Y R+ D G ++ S+ L A GL G + H +G HIY Sbjct: 165 CGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYD 215 >1B5E-A nrPDB Length = 246 Score = 67.3 bits (163), Expect = 7e-12, Method: Composition-based stats. Identities = 47/226 (20%), Positives = 81/226 (35%), Gaps = 42/226 (18%) Query: 49 DRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKI 108 D+TG T+ + G F L + + EL W+ S K++ + KI Sbjct: 27 DKTGVKTIEIIGASFVADEPFIFGALNDEY-----IQRELEWYKSKSLFVKDIPGETPKI 81 Query: 109 WDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTI 168 W S G++ YG W + E +Y+ Q + + Sbjct: 82 WQQVASSK------------GEINSNYG--WAIW------SEDNYA-----QYDMCLAEL 116 Query: 169 KTNPDDRRIIMCAWNPR-----DLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGV 223 NPD RR IM P + M+ C Q+ + + +++ + RS D+ G Sbjct: 117 GQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGF 176 Query: 224 PFNIA-SYALLTYMIAHITG------LKPGDFIHTLGDAHIYLNHI 262 + A +L +++ + K G I +G H+Y H Sbjct: 177 RNDYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRHF 222 >1ZCZ-A nrPDB Length = 464 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Query: 99 KELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQ 138 +EL KG +IW ++G+ FL S G E D+ + GF+ Sbjct: 31 RELHEKGWEIWASSGTAKFLKSNGI---EANDVSTITGFE 67 >6ECA-A nrPDB Length = 627 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 156 QGVDQLQRVIDTIKTNPDDRRIIMCAWN----PRDLPLMALPPCHALCQFYVVNSELSCQ 211 + +DQ++ +I K +P + AW+ P + A+P Q + + +L Q Sbjct: 413 RHIDQIRDLIKRDKNHPS-----VLAWSLFNEPDTIDENAVP---YFKQIFDESKDLDPQ 464 Query: 212 LYQRS 216 R+ Sbjct: 465 GRPRT 469 >1XDN-A nrPDB Length = 277 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 13/44 (29%) Query: 267 IQLQREPRP--FPKLRILRKVEKIDDFKA------EDFQIEGYN 302 +Q+QREP P P+L D K EDF + GY+ Sbjct: 143 VQIQREPFPQYSPELHFFA-----FDIKYSVSGAEEDFVLLGYD 181 >5XXB-n nrPDB Length = 105 Score = 27.6 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 24/60 (40%), Gaps = 6/60 (10%) Query: 23 EPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWK 82 PH QY ++ G R+ DR G FG Q + R + TTK++ K Sbjct: 18 RKHQPHKVSQYKKGKDSLVVQGKRRYDRKQKG----FGGQTKPIFRKK--AKTTKKIVLK 71 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.144 0.454 Lambda K H 0.267 0.0442 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,484,371 Number of Sequences: 36641 Number of extensions: 655821 Number of successful extensions: 1627 Number of sequences better than 10.0: 33 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 1468 Number of HSP's gapped (non-prelim): 80 length of query: 313 length of database: 10,336,785 effective HSP length: 97 effective length of query: 216 effective length of database: 6,782,608 effective search space: 1465043328 effective search space used: 1465043328 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.2 bits)