BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P04816
(369 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
1USI-A nrPDB 707 0.0
1Z15-A nrPDB 568 e-163
4QWV-A nrPDB 449 e-126
4N0Q-A nrPDB 254 5e-68
3IP9-A nrPDB 247 7e-66
4MLC-A nrPDB 124 5e-29
4GNR-A nrPDB 99 3e-21
4MPT-A nrPDB 74 1e-13
3I45-A nrPDB 67 2e-11
4XFK-A nrPDB 61 1e-09
4MS4-A nrPDB 51 8e-07
4EVS-A nrPDB 47 1e-05
4F06-A nrPDB 45 4e-05
4F11-A nrPDB 38 0.009
1QO0-A nrPDB 34 0.13
3H5L-A nrPDB 33 0.15
5X2M-A nrPDB 33 0.20
3CPG-A nrPDB 30 1.7
3WCZ-A nrPDB 30 1.9
2PCL-A nrPDB 30 2.0
3K4W-A nrPDB 29 3.0
2OV1-A nrPDB 29 3.2
1PQ4-A nrPDB 29 3.6
4ZTY-A nrPDB 29 3.9
3ILS-A nrPDB 28 4.6
4M88-A nrPDB 28 9.3
1RK6-A nrPDB 27 9.6
>1USI-A nrPDB
Length = 346
Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 345/346 (99%), Positives = 345/346 (99%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83
DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA
Sbjct: 1 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 60
Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL
Sbjct: 61 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 120
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203
DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK
Sbjct: 121 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 180
Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263
DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA
Sbjct: 181 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 240
Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323
AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL
Sbjct: 241 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 300
Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369
ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSST AK
Sbjct: 301 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTKAK 346
>1Z15-A nrPDB
Length = 344
Score = 568 bits (1465), Expect = e-163, Method: Compositional matrix adjust.
Identities = 273/346 (78%), Positives = 305/346 (88%), Gaps = 2/346 (0%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83
+DIKVAVVGAMSGP+AQ+GD EF GA QA+ DINAKGGIKG+KL V+YDDACDPKQAVA
Sbjct: 1 EDIKVAVVGAMSGPVAQYGDQEFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVA 60
Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
VANK+VNDGIKYVIGHLCSSSTQPASDIYEDEGILMI+P AT PELT RGYQ I+RT GL
Sbjct: 61 VANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGL 120
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203
DS QGPTAAKYILE VKPQRIAI+HDKQQYGEGLAR+VQDGLK NANVVFFDGITAGEK
Sbjct: 121 DSDQGPTAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEK 180
Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263
DFS L+ARLKKENIDFVYYGGY+PEMGQ+LRQAR+ GLKTQFMGPEGV N SLSNIAG++
Sbjct: 181 DFSTLVARLKKENIDFVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGES 240
Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323
AEG+LVT PK YDQ PAN+ IVDA+KA K+DPSG +VW TYAA+QSL L + SD+P
Sbjct: 241 AEGLLVTKPKNYDQVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQ--SDDPA 298
Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369
+ K LKAN +TV+GPL WDEKGDLKGF+FGVF WHA+G++T AK
Sbjct: 299 EIAKYLKANSVDTVMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK 344
>4QWV-A nrPDB
Length = 321
Score = 449 bits (1155), Expect = e-126, Method: Compositional matrix adjust.
Identities = 239/337 (70%), Positives = 258/337 (76%), Gaps = 26/337 (7%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83
DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA
Sbjct: 2 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 61
Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL
Sbjct: 62 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 121
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGIT---- 199
DSSQGPTAAKYILETVKPQR+ I+ D AA ++ D IT
Sbjct: 122 DSSQGPTAAKYILETVKPQRVLIVDD-----------------AAFMRMMLKDIITKAGY 164
Query: 200 --AGE-KDFSALIARLKKENIDFVYYGGYYPEMGQM--LRQARSVGLKTQFMGPEGVGNA 254
AGE + + + K+ D V PEM + +++ + + + +G
Sbjct: 165 EVAGEATNGREAVEKYKELKPDIVTMDITMPEMNGIDAIKEIMKIDPNAKIIVCSAMGQQ 224
Query: 255 SLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATAL 314
++ A A + PKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATAL
Sbjct: 225 AMVIEAIKAGAKDFIVKPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATAL 284
Query: 315 ERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKG 351
ERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKG
Sbjct: 285 ERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKG 321
>4N0Q-A nrPDB
Length = 354
Score = 254 bits (648), Expect = 5e-68, Method: Compositional matrix adjust.
Identities = 134/337 (39%), Positives = 199/337 (59%), Gaps = 3/337 (0%)
Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84
DI + V+ ++GP+A +GD GA A++ IN GGIKG+K+V DDA +PKQ V+
Sbjct: 10 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSA 69
Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144
AN+IV DGIK+V+G + + P SD+ + G+LM++P AT P+LT RG +++ RT G D
Sbjct: 70 ANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRD 129
Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204
Q A Y+L+ +K +++A+IHDK YG+GLA + + + V +D +T G+KD
Sbjct: 130 GQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKD 189
Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264
FSAL+ +LK + VY+GGY+ E G + RQ G++ +G EG+ N I G A
Sbjct: 190 FSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNA 249
Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGS-DEPL 323
+G L T K ++PA + + ALKA K P+ + YAAV+ + +ER GS D+
Sbjct: 250 QGTLFTNAKDATKNPAAKDAIQALKA-KNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSA 308
Query: 324 ALVKDLK-ANGANTVIGPLNWDEKGDLKGFDFGVFQW 359
A+ K L T IG L + E GDL F +F+W
Sbjct: 309 AVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKW 345
>3IP9-A nrPDB
Length = 356
Score = 247 bits (630), Expect = 7e-66, Method: Compositional matrix adjust.
Identities = 139/335 (41%), Positives = 205/335 (61%), Gaps = 1/335 (0%)
Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84
D+ +AV ++GP A +G GA QA KDINA GGI G+++ V DD DPKQ ++V
Sbjct: 2 DVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQGISV 61
Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144
ANK V DG+K+V+GH S + PAS++Y + GIL I+P ATNP T+RG + RT G D
Sbjct: 62 ANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRD 121
Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204
QG A KY+ + K ++AIIHDK YG+GLA + AA V ++G+ G+KD
Sbjct: 122 DQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKD 181
Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264
FSALI+++K+ + +Y+GG + E G ++RQA GLK + + +G+ + L++IAGDA
Sbjct: 182 FSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAKLVSGDGIVSNELASIAGDAV 241
Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLA 324
EG L T P N+ +V+ KA +P Y +YAA+Q++A A + GS EP
Sbjct: 242 EGTLNTFGPDPTLRPENKELVEKFKAAGFNPEA-YTLYSYAAMQAIAGAAKAAGSVEPEK 300
Query: 325 LVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQW 359
+ + LK T +G +++DEKGD K + +++W
Sbjct: 301 VAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEW 335
>4MLC-A nrPDB
Length = 356
Score = 124 bits (312), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 100/322 (31%), Positives = 155/322 (48%), Gaps = 14/322 (4%)
Query: 37 PIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIV-NDGIKY 95
P A D+ G A+++IN +GG++G KL V+ DD + ++ +A+A N GI+
Sbjct: 18 PFASLDDLFAEGLELAVQEINEQGGVQGRKLSLVKADDEAELEKGLAIAQAFADNAGIQA 77
Query: 96 VIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYI 155
VIGH S + PA+ IY+ G++M+SP +T+P+LT GY H+ R D A Y+
Sbjct: 78 VIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDHGYIHVFRNIPSDQEIARQLAIYL 137
Query: 156 LETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKE 215
E +R+ I + YG GLA + +D +A +V KD L + +
Sbjct: 138 AEQ-GHERMVIYYTDDSYGNGLANAFEDYARAQGITIVDRFNYYGNLKDLERLYDKWQAF 196
Query: 216 NIDFVYYGGYYPEMG-QMLRQARSVGLKTQFMGPEGVGNASLS----NIAGDAAEGMLV- 269
+D ++ G + L A+SVG++ + SL+ NI G AEG+LV
Sbjct: 197 GMDGIFIAKTATGGGTEFLVDAKSVGIEVPLIAGNSWDALSLTEDIENI-GMTAEGLLVG 255
Query: 270 --TMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVK 327
P+R D Q V+A + + P Y Y AV LA ALE++ P L +
Sbjct: 256 SFFNPQR--PDSRTQDFVEAFRREYGQPPTSYAAAGYDAVILLAEALEKSDLTHPATLAQ 313
Query: 328 DLKANGA-NTVIGPLNWDEKGD 348
L+ G V+G +D +GD
Sbjct: 314 GLRDLGPWEGVMGMHRFDGRGD 335
>4GNR-A nrPDB
Length = 353
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 67/227 (29%), Positives = 117/227 (51%), Gaps = 6/227 (2%)
Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVA 85
IK+ SG +A +G E GA+ A+ +INA GGI G ++ V+ D+ + +A +V
Sbjct: 8 IKIGFNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVT 67
Query: 86 NKIVNDG-IKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144
+V + V+G S +T A G+ +ISP AT LT +G ++ D
Sbjct: 68 TNLVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLT-KGQDYLFIGTFQD 126
Query: 145 SSQGPTAAKYILETVKPQRIAIIHDK-QQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203
S QG + Y+ E + +++ + D Y +G+A+S ++ K +V + AG+
Sbjct: 127 SFQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKG---EIVADETFVAGDT 183
Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEG 250
DF A + ++K ++ D + GYY E G+++ QAR +G+ +G +G
Sbjct: 184 DFQAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDG 230
>4MPT-A nrPDB
Length = 380
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 39/347 (11%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKL-VGVEYDDACDPKQA 81
AD IK+ + A++GP ++G+ A++ NAKGGI G K+ + + DD +P +A
Sbjct: 4 ADTIKIGMTSALTGPYNEFGEGNRRAVELAVEQWNAKGGINGKKIEIAMLLDDQLNPDRA 63
Query: 82 VAVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQ----- 135
V I+ N I +IG S D+ + +G ++P A P +T G +
Sbjct: 64 VQNIRAILDNKDIVGIIGPAGSGPMLAVIDMVQADGRPYMNPIAQTPVVTYPGEKTGEKP 123
Query: 136 --HIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYG----EGLARSVQDGLKAAN 189
++ A + + +Y+ + K R+ IIH+ YG + LA S+ K
Sbjct: 124 RPNVFSFALQNDIEAVAMGEYLAKKFK--RVGIIHESTAYGVTGVDYLAASIA---KNGG 178
Query: 190 ANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPE 249
A V D G +D +A +AR+K+ N+D + G ++ + R + +
Sbjct: 179 AKPVATDSYNQGAQDMTAQVARMKRANVDAIAAIGLGKDLAVLRRTMARLNVNVPLAASN 238
Query: 250 GVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADK----------KDPSGPY 299
G AG+ G L TM + +P D KA K DP P
Sbjct: 239 GALGQPYQEGAGELTLGTLGTMIGAFG-NPMRAPAADFAKAYKAKYGTDRWWGNDPENPQ 297
Query: 300 VWIT------YAAVQSLATALERTGSDEPLALVKDLKA----NGANT 336
+++ Y A L + S +P A++ +++ G NT
Sbjct: 298 LFMAISVSNGYDAANILFEGIRLANSTDPKAVIAAIESIKDYQGVNT 344
>3I45-A nrPDB
Length = 387
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 80/309 (25%), Positives = 139/309 (44%), Gaps = 19/309 (6%)
Query: 47 NGARQAIKDINAKGGIKGDK-LVGVEYDDACDPKQAVAVANKIVN-DGIKYVIGHLCSSS 104
NG + A++ INA GG+ G + L + DD DP +AV A +++ G+ + G S
Sbjct: 26 NGWQLAVEQINAAGGLLGGRPLEVISRDDGGDPGKAVTAAQELLTRHGVHALAGTFLSHV 85
Query: 105 TQPASDIYEDEGILMISPGATNPELT-QRGYQHIMRTAGLDSSQGPTAAKYILETVKPQR 163
SD +L ++ LT ++G ++ R Q A + + R
Sbjct: 86 GLAVSDFARQRKVLFMASEPLTDALTWEKGNRYTYRLRPSTYMQAAMLAAEAAK-LPITR 144
Query: 164 IAIIHDKQQYGEGLARSVQDGLKAANANVVFF-DGITAGEK-DFSALIARLKKENIDFVY 221
A I +YG+ ++ L AA V F + A K D + L++ + ++
Sbjct: 145 WATIAPNYEYGQSAVARFKELLLAARPEVTFVAEQWPALYKLDAGPTVQALQQAEPEGLF 204
Query: 222 YGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNAS-----LSNIAGDAAEGMLVTMPKRYD 276
+ ++ + +R+ R GL F G + V + L+ + +A EG +VT YD
Sbjct: 205 NVLFGADLPKFVREGRVRGL---FAGRQVVSMLTGEPEYLNPLKDEAPEGWIVTGYPWYD 261
Query: 277 QDPA-NQGIVDALKADKKDPSGPYV--WITYAAVQSLATALERTGSDEPLALVKDLKANG 333
D A ++ V+A +A K+ P+V + Y + ++A A E+ G E LV+ LK
Sbjct: 262 IDTAPHRAFVEAYRARWKE--DPFVGSLVGYNTLTAMAVAFEKAGGTESETLVETLKDMA 319
Query: 334 ANTVIGPLN 342
+T +GPL+
Sbjct: 320 FSTPMGPLS 328
>4XFK-A nrPDB
Length = 399
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 82/320 (25%), Positives = 143/320 (44%), Gaps = 41/320 (12%)
Query: 15 LAISHTAMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDD 74
+A H A+ +K+A+V +SGP A G + + IN GG G+K+ +EYD+
Sbjct: 1 MAHHHHHHAEPLKIALVETLSGPQASTGLLYRAAVLYQLGKINEAGGFNGEKIQILEYDN 60
Query: 75 ACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYED----------EGILMISPGA 124
P A + DG + ++ SS+ A I ED + +L ++ GA
Sbjct: 61 QGGPVGAADRVKAAIADGAQIIV---QGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGA 117
Query: 125 TNPELT-QRGYQHIMRTAGLDSSQGPTAAKYILET-VKPQRIAIIHDKQQYGEGLARSVQ 182
ELT + + + R + + + T A+ + + + +R I+ +G + +V
Sbjct: 118 EALELTGSKCHFYHFRFSPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTV- 176
Query: 183 DGLKAANANVVFFDGI--TAGE----KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQA 236
ANA + ++ + T E +DFS +A+++ N+D V+ G + ++ +++ A
Sbjct: 177 ----VANAKEIGYEVVDKTLHEVNKIQDFSPYVAKIQAANVDTVFTGNWSNDLLLLMKAA 232
Query: 237 RSVGLKTQFMG-----PEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKAD 291
GLK +F P +GN AG AEG +V+ P + AN A D
Sbjct: 233 SGAGLKAKFATSFLDQPGNIGN------AGAIAEGHIVSTPFNPE---ANGEASMAFAED 283
Query: 292 KKDPSGPY-VWITYAAVQSL 310
K +G Y ++ AAV L
Sbjct: 284 YKKVTGHYPSYVEPAAVFGL 303
>4MS4-A nrPDB
Length = 420
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 36/146 (24%), Positives = 71/146 (48%), Gaps = 4/146 (2%)
Query: 52 AIKDINAKGGIKGD-KLVGVEYDDACDPKQAVAVANKIV-NDGIKYVIGHLCSSSTQPAS 109
A++D+N++ I D +L + +D CDP QA +++ ND IK ++ CSS + +
Sbjct: 31 ALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVA 90
Query: 110 DIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIH 168
+ ++++S G+++P L+ R + RT + PT K + E ++IA I
Sbjct: 91 EAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVK-LFEKWGWKKIATIQ 149
Query: 169 DKQQYGEGLARSVQDGLKAANANVVF 194
+ +++ +K A + F
Sbjct: 150 QTTEVFTSTLDDLEERVKEAGIEITF 175
>4EVS-A nrPDB
Length = 371
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 70/281 (24%), Positives = 123/281 (43%), Gaps = 25/281 (8%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIK-GDKLVGVEYDDAC--DPK 79
AD IKV V+G MSGP A +G + I A+ G K G V Y D +P
Sbjct: 3 ADTIKVGVIGTMSGPYALFG----QNFKMGIDAWVAEHGNKVGGHTVEFVYRDEVSPNPA 58
Query: 80 QAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIM 138
Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ +I+
Sbjct: 59 QSKALAQELIVKEKVQYIAGLYFTPNAMAVAPLLQEAKVPMVVLNAATSSITEKS-PYIV 117
Query: 139 RTAGLDSSQGPTAAKYILETVKPQRIAI-IHDKQQYGEGL--ARSVQDGLKAANANVVFF 195
RT+ Q A + + +++AI + D YG G+ + + +A +VV
Sbjct: 118 RTS-FTMFQNTVPAAKVAKQKGAKKVAIAVSD---YGPGIDAETAFKKTFEAEGGSVVEA 173
Query: 196 DGITAGEKDFSALIARLKKENID--FVYYGGYYPEMG----QMLRQARSVGLKTQFMGPE 249
+ DF ++ R+K D F + P +G + ++ G+K G +
Sbjct: 174 VRMPLATTDFGPIMQRIKDSGADMIFTFLPAGPPTLGFVKAYIDNGLKAAGVKLMSTG-D 232
Query: 250 GVGNASLSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALK 289
V L NI GD+ G+L T D P N+ + L+
Sbjct: 233 VVTEPDLPNI-GDSGIGILSTYHYAVSHDSPENKAFLALLQ 272
>4F06-A nrPDB
Length = 371
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 51/209 (24%), Positives = 96/209 (45%), Gaps = 22/209 (10%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVG--VEY----DDAC 76
AD IKV V+G MSGP A +G G I+A G+K+ G VE+ + +
Sbjct: 3 ADTIKVGVIGTMSGPYALFGKNYKMG-------IDAWVAEHGNKVAGHTVEFVYRDEVSP 55
Query: 77 DPKQAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQ 135
+P Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++
Sbjct: 56 NPAQSKALAQELIVKEKVQYLAGLYFTPNAMAVAPLLQEAKVPMVVMNAATSSITEKS-P 114
Query: 136 HIMRTAGLDSSQGPTAAKYILETVKPQRIAI-IHDKQQYGEGL--ARSVQDGLKAANANV 192
+I+RT+ Q A + + ++AI + D YG G+ + + +A V
Sbjct: 115 YIVRTS-FTMFQNTVPAAKVAKQKGATKVAIAVSD---YGPGIDAETAFKKTFEAEGGKV 170
Query: 193 VFFDGITAGEKDFSALIARLKKENIDFVY 221
V + DF ++ R+K D ++
Sbjct: 171 VEAVRMPLSTTDFGPIMQRIKNSGADMIF 199
>4F11-A nrPDB
Length = 433
Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 72 YDDACDPKQAVAVANKIVNDGIKY------VIGHLCSSSTQPASDIYEDEGILMISPGAT 125
YD CD + + K D IKY V G +C S T ++ + ++ +S AT
Sbjct: 63 YDTECDNAKGL----KAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAAT 118
Query: 126 NPELT-QRGYQHIMRTAGLDSSQGPTAAKYILETVKPQRI-AIIHDKQQYGE 175
P L ++ Y + RT D++ P K +L+ + +R+ + D Q++ E
Sbjct: 119 TPVLADKKKYPYFFRTVPSDNAVNPAILK-LLKHYQWKRVGTLTQDVQRFSE 169
>1QO0-A nrPDB
Length = 385
Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 48 GARQAIKDINAKGGIKGDKLVGVEYDDACDP-KQAVAVANKIVNDGIKYVIGHLCSSSTQ 106
GA A++ +N +GG+ G + + D DP + + + I N G+++++G S + +
Sbjct: 30 GALLAVEQLNREGGVGGRPIETLSQDPGGDPDRYRLCAEDFIRNRGVRFLVGCYMSHTRK 89
Query: 107 PASDIYEDEGILMISP 122
+ E L+ P
Sbjct: 90 AVMPVVERADALLCYP 105
>3H5L-A nrPDB
Length = 419
Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 10/117 (8%)
Query: 157 ETVKPQ-RIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKE 215
E +P +IAII Y +A +++DG +V F+ + D+ +A+L+ +
Sbjct: 159 EFSRPNNKIAIITGPGIYSVNIANAIRDGAGEYGYDVSLFETVAIPVSDWGPTLAKLRAD 218
Query: 216 NIDFVYYGGYYPE-----MGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGM 267
+ +YP+ M Q + + + Q+ G A+ +IAGD + G+
Sbjct: 219 PPAVIVVTHFYPQDQALFMNQFMTDPTNSLVYLQY----GASLAAFRDIAGDNSVGV 271
>5X2M-A nrPDB
Length = 461
Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 13/83 (15%)
Query: 294 DPSGPYVWITYAAVQSLATALE---RTGSD--------EPLALVKDLKANGANTVIGPLN 342
DPS + + YAAV ++A AL R GSD P ++++LK + + +
Sbjct: 343 DPS--FSFPVYAAVYAIAHALHNTLRCGSDRCPKNITVHPHMILEELKKSNFTLLNQTVQ 400
Query: 343 WDEKGDLKGFDFGVFQWHADGSS 365
+DE GD K V W++ G++
Sbjct: 401 FDENGDPKFGSLSVVFWNSSGNA 423
>3CPG-A nrPDB
Length = 282
Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 20/81 (24%)
Query: 69 GVEYDDACDPKQAVAVANKI-VNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNP 127
G E CDP A+ +A KI DGI+ +G++ I +
Sbjct: 171 GEESKSGCDPAHAIRIAQKIGTLDGIEL-------------------QGLMTIGAHVHDE 211
Query: 128 ELTQRGYQHIMRTAGLDSSQG 148
+ +RG+ H+ +T L + G
Sbjct: 212 TVIRRGFSHLRKTRDLILASG 232
>3WCZ-A nrPDB
Length = 308
Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 30/136 (22%), Positives = 58/136 (42%), Gaps = 23/136 (16%)
Query: 165 AIIHDKQQYGEGLARSVQDGLKAANANVV---FFDGITAGEKDFSALIARLKKENIDFV- 220
A+ D++Q G+G+A ++ +GL V ++ A ++ AL LKK +D++
Sbjct: 56 AVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYID 115
Query: 221 YYGGYYP---------------EMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAE 265
Y ++P E Q ++ AR +GL GV N + + I +
Sbjct: 116 LYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI----GVSNFNATQITRLVSN 171
Query: 266 GMLVTMPKRYDQDPAN 281
+ + + + +P N
Sbjct: 172 SYIRPVINQIEVNPTN 187
>2PCL-A nrPDB
Length = 224
Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 9/81 (11%)
Query: 64 GDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV----IGHLCSSSTQPASDIYE--DEG- 116
GDKL Y+ + +Q VA+A + N+ I G+L S++T+ DI+ +EG
Sbjct: 131 GDKLSRKPYELSGGEQQRVAIARALANEPILLFADEPTGNLDSANTKRVMDIFLKINEGG 190
Query: 117 --ILMISPGATNPELTQRGYQ 135
I+M++ ELT R +
Sbjct: 191 TSIVMVTHERELAELTHRTLE 211
>3K4W-A nrPDB
Length = 291
Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Query: 55 DINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV---------IGHLCSSST 105
D+ A DK V +A K+A+A +I++ GI+ V H+
Sbjct: 81 DVAAVAKAYPDKFHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGVWATPMHVDDRRL 140
Query: 106 QPASDIYEDEGI--LMISPGATNPELTQRGYQHIMRTAG 142
P ED GI +M++ G P++T +HI R G
Sbjct: 141 YPLYAFCEDNGIPVIMMTGGNAGPDITYTNPEHIDRVLG 179
>2OV1-A nrPDB
Length = 260
Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 6/49 (12%)
Query: 160 KPQRIAIIHDKQQY---GEGLARSVQDGLKAANANVVFFD---GITAGE 202
KPQ++A + + + Y G G + + LKAANAN+ D GIT E
Sbjct: 42 KPQQLAALSEAEAYVLIGLGFEQPWLEKLKAANANMKLIDSAQGITPLE 90
>1PQ4-A nrPDB
Length = 291
Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 6/51 (11%)
Query: 160 KPQRIAIIHDKQQY---GEGLARSVQDGLKAANANVVFFD---GITAGEKD 204
KPQ++A + + + Y G G + + LKAANAN+ D GIT E +
Sbjct: 42 KPQQLAALSEAEAYVLIGLGFEQPWLEKLKAANANMKLIDSAQGITPLEME 92
>4ZTY-A nrPDB
Length = 769
Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 24/47 (51%)
Query: 288 LKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA 334
L ++KK PS Y W ++A + A EP A+ +L+AN A
Sbjct: 340 LASEKKLPSDVYEWFSFAVEKVKEVATLAKAVTEPEAVKAELEANAA 386
>3ILS-A nrPDB
Length = 265
Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 227 PEMGQMLRQARSVGLKTQFMGPEGVGN----ASLSNIAGDAAEGMLVTMPKRYDQDPANQ 282
P +L+ V KT FM P+G G+ ASL + D A +V + Y +DP N
Sbjct: 7 PSTSVVLQGLPMVARKTLFMLPDGGGSAFSYASLPRLKSDTA---VVGLNCPYARDPENM 63
Query: 283 GIVDALKAD-------KKDPSGPY 299
+ ++ P GPY
Sbjct: 64 NCTHGAMIESFCNEIRRRQPRGPY 87
>4M88-A nrPDB
Length = 357
Score = 27.7 bits (60), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 23/49 (46%)
Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDD 74
I + +G +GP+A G + + N GGI+G KL E DD
Sbjct: 5 IVLGQIGPFTGPLAADAAGLNQGIKAYLAQANKAGGIRGQKLTLFEADD 53
>1RK6-A nrPDB
Length = 496
Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 32 GAMSGPIAQWGDMEFNGARQAIKDINAKG-----GIKGDKLVGVEYDDACDPKQAVAVAN 86
G+MS P A D +G I NA G G++GD++ V A ++ + VA
Sbjct: 11 GSMSQPDATPFDYILSGG-TVIDGTNAPGRLADVGVRGDRIAAVGDLSASSARRRIDVAG 69
Query: 87 KIVNDGI 93
K+V+ G
Sbjct: 70 KVVSPGF 76
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
1USI-A nrPDB 477 e-135
1Z15-A nrPDB 437 e-123
4QWV-A nrPDB 347 4e-96
3IP9-A nrPDB 346 1e-95
4N0Q-A nrPDB 338 2e-93
4MLC-A nrPDB 294 3e-80
3I45-A nrPDB 263 6e-71
4MPT-A nrPDB 251 3e-67
4EVS-A nrPDB 225 3e-59
4XFK-A nrPDB 221 3e-58
4F06-A nrPDB 218 3e-57
4GNR-A nrPDB 215 2e-56
4MS4-A nrPDB 165 3e-41
Sequences not found previously or not previously below threshold:
1QO0-A nrPDB 112 3e-25
3H5L-A nrPDB 104 7e-23
4F11-A nrPDB 81 6e-16
3LMK-A nrPDB 81 8e-16
6N4Y-A nrPDB 79 2e-15
6N4X-A nrPDB 79 2e-15
5X2M-A nrPDB 77 1e-14
6BT5-A nrPDB 77 1e-14
1ISS-A nrPDB 75 5e-14
5C5C-A nrPDB 74 7e-14
4M88-A nrPDB 64 8e-11
5X2N-B nrPDB 54 1e-07
1YK0-A nrPDB 44 1e-04
2YFH-A nrPDB 36 0.023
5L2E-A nrPDB 36 0.033
3NV9-A nrPDB 34 0.16
4FHN-X nrPDB 32 0.39
4ZTY-A nrPDB 31 1.00
3E8L-C nrPDB 31 1.2
3WWM-A nrPDB 30 1.6
4P98-A nrPDB 30 1.7
4KWT-A nrPDB 29 3.3
3MW8-A nrPDB 29 4.1
3DAF-A nrPDB 28 6.6
3CPT-A nrPDB 28 6.9
4AQ4-A nrPDB 28 8.0
3S99-A nrPDB 27 9.3
>1USI-A nrPDB
Length = 346
Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats.
Identities = 345/346 (99%), Positives = 345/346 (99%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83
DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA
Sbjct: 1 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 60
Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL
Sbjct: 61 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 120
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203
DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK
Sbjct: 121 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 180
Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263
DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA
Sbjct: 181 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 240
Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323
AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL
Sbjct: 241 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 300
Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369
ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSST AK
Sbjct: 301 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTKAK 346
>1Z15-A nrPDB
Length = 344
Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats.
Identities = 273/346 (78%), Positives = 305/346 (88%), Gaps = 2/346 (0%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83
+DIKVAVVGAMSGP+AQ+GD EF GA QA+ DINAKGGIKG+KL V+YDDACDPKQAVA
Sbjct: 1 EDIKVAVVGAMSGPVAQYGDQEFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVA 60
Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
VANK+VNDGIKYVIGHLCSSSTQPASDIYEDEGILMI+P AT PELT RGYQ I+RT GL
Sbjct: 61 VANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGL 120
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203
DS QGPTAAKYILE VKPQRIAI+HDKQQYGEGLAR+VQDGLK NANVVFFDGITAGEK
Sbjct: 121 DSDQGPTAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEK 180
Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263
DFS L+ARLKKENIDFVYYGGY+PEMGQ+LRQAR+ GLKTQFMGPEGV N SLSNIAG++
Sbjct: 181 DFSTLVARLKKENIDFVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGES 240
Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323
AEG+LVT PK YDQ PAN+ IVDA+KA K+DPSG +VW TYAA+QSL L + SD+P
Sbjct: 241 AEGLLVTKPKNYDQVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQ--SDDPA 298
Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369
+ K LKAN +TV+GPL WDEKGDLKGF+FGVF WHA+G++T AK
Sbjct: 299 EIAKYLKANSVDTVMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK 344
>4QWV-A nrPDB
Length = 321
Score = 347 bits (891), Expect = 4e-96, Method: Composition-based stats.
Identities = 231/330 (70%), Positives = 253/330 (76%), Gaps = 12/330 (3%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83
DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA
Sbjct: 2 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 61
Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL
Sbjct: 62 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 121
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203
DSSQGPTAAKYILETVKPQR+ I+ D + + ++ +
Sbjct: 122 DSSQGPTAAKYILETVKPQRVLIVDD---------AAFMRMMLKDIITKAGYE-VAGEAT 171
Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQM--LRQARSVGLKTQFMGPEGVGNASLSNIAG 261
+ + + K+ D V PEM + +++ + + + +G ++ A
Sbjct: 172 NGREAVEKYKELKPDIVTMDITMPEMNGIDAIKEIMKIDPNAKIIVCSAMGQQAMVIEAI 231
Query: 262 DAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDE 321
A + PKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDE
Sbjct: 232 KAGAKDFIVKPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDE 291
Query: 322 PLALVKDLKANGANTVIGPLNWDEKGDLKG 351
PLALVKDLKANGANTVIGPLNWDEKGDLKG
Sbjct: 292 PLALVKDLKANGANTVIGPLNWDEKGDLKG 321
>3IP9-A nrPDB
Length = 356
Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats.
Identities = 139/335 (41%), Positives = 205/335 (61%), Gaps = 1/335 (0%)
Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84
D+ +AV ++GP A +G GA QA KDINA GGI G+++ V DD DPKQ ++V
Sbjct: 2 DVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQGISV 61
Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144
ANK V DG+K+V+GH S + PAS++Y + GIL I+P ATNP T+RG + RT G D
Sbjct: 62 ANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRD 121
Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204
QG A KY+ + K ++AIIHDK YG+GLA + AA V ++G+ G+KD
Sbjct: 122 DQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKD 181
Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264
FSALI+++K+ + +Y+GG + E G ++RQA GLK + + +G+ + L++IAGDA
Sbjct: 182 FSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAKLVSGDGIVSNELASIAGDAV 241
Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLA 324
EG L T P N+ +V+ KA +P Y +YAA+Q++A A + GS EP
Sbjct: 242 EGTLNTFGPDPTLRPENKELVEKFKAAGFNPE-AYTLYSYAAMQAIAGAAKAAGSVEPEK 300
Query: 325 LVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQW 359
+ + LK T +G +++DEKGD K + +++W
Sbjct: 301 VAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEW 335
>4N0Q-A nrPDB
Length = 354
Score = 338 bits (867), Expect = 2e-93, Method: Composition-based stats.
Identities = 134/337 (39%), Positives = 199/337 (59%), Gaps = 3/337 (0%)
Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84
DI + V+ ++GP+A +GD GA A++ IN GGIKG+K+V DDA +PKQ V+
Sbjct: 10 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSA 69
Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144
AN+IV DGIK+V+G + + P SD+ + G+LM++P AT P+LT RG +++ RT G D
Sbjct: 70 ANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRD 129
Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204
Q A Y+L+ +K +++A+IHDK YG+GLA + + + V +D +T G+KD
Sbjct: 130 GQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKD 189
Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264
FSAL+ +LK + VY+GGY+ E G + RQ G++ +G EG+ N I G A
Sbjct: 190 FSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNA 249
Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGS-DEPL 323
+G L T K ++PA + + ALKA K P+ + YAAV+ + +ER GS D+
Sbjct: 250 QGTLFTNAKDATKNPAAKDAIQALKA-KNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSA 308
Query: 324 ALVKDLKA-NGANTVIGPLNWDEKGDLKGFDFGVFQW 359
A+ K L T IG L + E GDL F +F+W
Sbjct: 309 AVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKW 345
>4MLC-A nrPDB
Length = 356
Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats.
Identities = 103/348 (29%), Positives = 163/348 (46%), Gaps = 13/348 (3%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAV 82
+++I + V + P A D+ G A+++IN +GG++G KL V+ DD + ++ +
Sbjct: 8 SEEIFIGV----AWPFASLDDLFAEGLELAVQEINEQGGVQGRKLSLVKADDEAELEKGL 63
Query: 83 AVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTA 141
A+A N GI+ VIGH S + PA+ IY+ G++M+SP +T+P+LT GY H+ R
Sbjct: 64 AIAQAFADNAGIQAVIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDHGYIHVFRNI 123
Query: 142 GLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAG 201
D A Y+ E +R+ I + YG GLA + +D +A +V
Sbjct: 124 PSDQEIARQLAIYLAEQ-GHERMVIYYTDDSYGNGLANAFEDYARAQGITIVDRFNYYGN 182
Query: 202 EKDFSALIARLKKENIDFVYYGGYYPEMG-QMLRQARSVGLKTQFMGPEGVGNASLSNI- 259
KD L + + +D ++ G + L A+SVG++ + SL+
Sbjct: 183 LKDLERLYDKWQAFGMDGIFIAKTATGGGTEFLVDAKSVGIEVPLIAGNSWDALSLTEDI 242
Query: 260 --AGDAAEGMLVTMPKRYD-QDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALER 316
G AEG+LV D Q V+A + + P Y Y AV LA ALE+
Sbjct: 243 ENIGMTAEGLLVGSFFNPQRPDSRTQDFVEAFRREYGQPPTSYAAAGYDAVILLAEALEK 302
Query: 317 TGSDEPLALVKDLKANGA-NTVIGPLNWDEKGDLKGFDFGVFQWHADG 363
+ P L + L+ G V+G +D +GD G D V + DG
Sbjct: 303 SDLTHPATLAQGLRDLGPWEGVMGMHRFDGRGDDIG-DLVVLKKMKDG 349
>3I45-A nrPDB
Length = 387
Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats.
Identities = 81/331 (24%), Positives = 145/331 (43%), Gaps = 16/331 (4%)
Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDK-LVGVEYDDACDPKQAV 82
+ I++ + + S I + NG + A++ INA GG+ G + L + DD DP +AV
Sbjct: 4 EAIRIGEINSYS-QIPAFTLPYRNGWQLAVEQINAAGGLLGGRPLEVISRDDGGDPGKAV 62
Query: 83 AVANKIVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELT-QRGYQHIMRT 140
A +++ G+ + G S SD +L ++ LT ++G ++ R
Sbjct: 63 TAAQELLTRHGVHALAGTFLSHVGLAVSDFARQRKVLFMASEPLTDALTWEKGNRYTYRL 122
Query: 141 AGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVF-FDGIT 199
Q A + R A I +YG+ ++ L AA V F +
Sbjct: 123 RPSTYMQAAMLAAEAA-KLPITRWATIAPNYEYGQSAVARFKELLLAARPEVTFVAEQWP 181
Query: 200 AGEK-DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNAS--- 255
A K D + L++ + ++ + ++ + +R+ R GL F G + V +
Sbjct: 182 ALYKLDAGPTVQALQQAEPEGLFNVLFGADLPKFVREGRVRGL---FAGRQVVSMLTGEP 238
Query: 256 --LSNIAGDAAEGMLVTMPKRYDQDPA-NQGIVDALKADKKDPSGPYVWITYAAVQSLAT 312
L+ + +A EG +VT YD D A ++ V+A +A K+ + Y + ++A
Sbjct: 239 EYLNPLKDEAPEGWIVTGYPWYDIDTAPHRAFVEAYRARWKEDPFVGSLVGYNTLTAMAV 298
Query: 313 ALERTGSDEPLALVKDLKANGANTVIGPLNW 343
A E+ G E LV+ LK +T +GPL++
Sbjct: 299 AFEKAGGTESETLVETLKDMAFSTPMGPLSF 329
>4MPT-A nrPDB
Length = 380
Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats.
Identities = 81/345 (23%), Positives = 139/345 (40%), Gaps = 33/345 (9%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVG-VEYDDACDPKQA 81
AD IK+ + A++GP ++G+ A++ NAKGGI G K+ + DD +P +A
Sbjct: 4 ADTIKIGMTSALTGPYNEFGEGNRRAVELAVEQWNAKGGINGKKIEIAMLLDDQLNPDRA 63
Query: 82 VAVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGY------ 134
V I+ N I +IG S D+ + +G ++P A P +T G
Sbjct: 64 VQNIRAILDNKDIVGIIGPAGSGPMLAVIDMVQADGRPYMNPIAQTPVVTYPGEKTGEKP 123
Query: 135 -QHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGL-KAANANV 192
++ A + + +Y+ + +R+ IIH+ YG + + K A
Sbjct: 124 RPNVFSFALQNDIEAVAMGEYLAKKF--KRVGIIHESTAYGVTGVDYLAASIAKNGGAKP 181
Query: 193 VFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVG 252
V D G +D +A +AR+K+ N+D + G ++ + R + + G
Sbjct: 182 VATDSYNQGAQDMTAQVARMKRANVDAIAAIGLGKDLAVLRRTMARLNVNVPLAASNGAL 241
Query: 253 NASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADK----------KDPSGPYVWI 302
AG+ G L TM + +P D KA K DP P +++
Sbjct: 242 GQPYQEGAGELTLGTLGTMIGAFG-NPMRAPAADFAKAYKAKYGTDRWWGNDPENPQLFM 300
Query: 303 ------TYAAVQSLATALERTGSDEPLALVKDLKA----NGANTV 337
Y A L + S +P A++ +++ G NT
Sbjct: 301 AISVSNGYDAANILFEGIRLANSTDPKAVIAAIESIKDYQGVNTA 345
>4EVS-A nrPDB
Length = 371
Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats.
Identities = 76/336 (22%), Positives = 136/336 (40%), Gaps = 22/336 (6%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIK-GDKLVGVEYDDA--CDPK 79
AD IKV V+G MSGP A +G G I A+ G K G V Y D +P
Sbjct: 3 ADTIKVGVIGTMSGPYALFGQNFKMG----IDAWVAEHGNKVGGHTVEFVYRDEVSPNPA 58
Query: 80 QAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIM 138
Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ +I+
Sbjct: 59 QSKALAQELIVKEKVQYIAGLYFTPNAMAVAPLLQEAKVPMVVLNAATSSITEKS-PYIV 117
Query: 139 RTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI 198
RT+ Q A + + +++AI G + + +A +VV +
Sbjct: 118 RTS-FTMFQNTVPAAKVAKQKGAKKVAIAVSDYGPGIDAETAFKKTFEAEGGSVVEAVRM 176
Query: 199 TAGEKDFSALIARLKKENIDFV--YYGGYYPEMG----QMLRQARSVGLKTQFMGPEGVG 252
DF ++ R+K D + + P +G + ++ G+K G + V
Sbjct: 177 PLATTDFGPIMQRIKDSGADMIFTFLPAGPPTLGFVKAYIDNGLKAAGVKLMSTG-DVVT 235
Query: 253 NASLSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALKADKKDPSGP--YVWITYAAVQS 309
L NI GD+ G+L T D P N+ + L+ Y +
Sbjct: 236 EPDLPNI-GDSGIGILSTYHYAVSHDSPENKAFLALLQKGGAKLGDVTMTSVAAYDGARL 294
Query: 310 LATALERTGS-DEPLALVKDLKANGANTVIGPLNWD 344
+ +E TG +P + +K + GP++ D
Sbjct: 295 IYKMIEATGGKQDPEKAIAAVKDMKWTSPRGPVSID 330
>4XFK-A nrPDB
Length = 399
Score = 221 bits (564), Expect = 3e-58, Method: Composition-based stats.
Identities = 81/349 (23%), Positives = 146/349 (41%), Gaps = 28/349 (8%)
Query: 15 LAISHTAMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDD 74
+A H A+ +K+A+V +SGP A G + + IN GG G+K+ +EYD+
Sbjct: 1 MAHHHHHHAEPLKIALVETLSGPQASTGLLYRAAVLYQLGKINEAGGFNGEKIQILEYDN 60
Query: 75 ACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYED----------EGILMISPGA 124
P A + DG + ++ SS+ A I ED + +L ++ GA
Sbjct: 61 QGGPVGAADRVKAAIADGAQIIV---QGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGA 117
Query: 125 TNPELT-QRGYQHIMRTAGLDSSQGPTAAKYILET-VKPQRIAIIHDKQQYGEGLARSVQ 182
ELT + + + R + + + T A+ + + + +R I+ +G + +V
Sbjct: 118 EALELTGSKCHFYHFRFSPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTVV 177
Query: 183 DGLKAANANVVFFDGITAGE-KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGL 241
K VV + +DFS +A+++ N+D V+ G + ++ +++ A GL
Sbjct: 178 ANAKEIGYEVVDKTLHEVNKIQDFSPYVAKIQAANVDTVFTGNWSNDLLLLMKAASGAGL 237
Query: 242 KTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPY-V 300
K +F + AG AEG +V+ P + AN A D K +G Y
Sbjct: 238 KAKFAT-SFLDQPGNIGNAGAIAEGHIVSTPFNPE---ANGEASMAFAEDYKKVTGHYPS 293
Query: 301 WITYAAVQSLATALERTGSDEPLA-------LVKDLKANGANTVIGPLN 342
++ AAV L E + +P + ++ T +G +
Sbjct: 294 YVEPAAVFGLQLFGEALKNVKPGEGKINTTDIALAIENASVKTPMGDYS 342
>4F06-A nrPDB
Length = 371
Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats.
Identities = 76/336 (22%), Positives = 137/336 (40%), Gaps = 22/336 (6%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIK--GDKLVGVEYDD-ACDPK 79
AD IKV V+G MSGP A +G G I A+ G K G + V D+ + +P
Sbjct: 3 ADTIKVGVIGTMSGPYALFGKNYKMG----IDAWVAEHGNKVAGHTVEFVYRDEVSPNPA 58
Query: 80 QAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIM 138
Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ +I+
Sbjct: 59 QSKALAQELIVKEKVQYLAGLYFTPNAMAVAPLLQEAKVPMVVMNAATSSITEKS-PYIV 117
Query: 139 RTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI 198
RT+ Q A + + ++AI G + + +A VV +
Sbjct: 118 RTS-FTMFQNTVPAAKVAKQKGATKVAIAVSDYGPGIDAETAFKKTFEAEGGKVVEAVRM 176
Query: 199 TAGEKDFSALIARLKKENIDFV--YYGGYYPEMG----QMLRQARSVGLKTQFMGPEGVG 252
DF ++ R+K D + + P +G + ++ G+K G + V
Sbjct: 177 PLSTTDFGPIMQRIKNSGADMIFTFLPAGPPTLGFVKAYIDNGLKAGGVKLMSTG-DVVT 235
Query: 253 NASLSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALKA--DKKDPSGPYVWITYAAVQS 309
L NI G+A G+L T D P N+ + L+ K D Y +
Sbjct: 236 EPDLPNI-GEAGLGILSTYHYAVSHDSPENKAFLALLQKGGAKLDEVTMTSVAAYDGARL 294
Query: 310 LATALERT-GSDEPLALVKDLKANGANTVIGPLNWD 344
+ +E T G +P + +K + G ++ D
Sbjct: 295 IYKMIEATSGKSDPDKAIAAVKGMKWVSPRGEVSID 330
>4GNR-A nrPDB
Length = 353
Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats.
Identities = 81/326 (24%), Positives = 147/326 (45%), Gaps = 12/326 (3%)
Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84
IK+ SG +A +G E GA+ A+ +INA GGI G ++ V+ D+ + +A +V
Sbjct: 7 TIKIGFNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASV 66
Query: 85 ANKIVND-GIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
+V + V+G S +T A G+ +ISP AT LT +G ++
Sbjct: 67 TTNLVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLT-KGQDYLFIGTFQ 125
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDK-QQYGEGLARSVQDGLKAANANVVFFDGITAGE 202
DS QG + Y+ E + +++ + D Y +G+A+S ++ K +V + AG+
Sbjct: 126 DSFQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYK---GEIVADETFVAGD 182
Query: 203 KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGD 262
DF A + ++K ++ D + GYY E G+++ QAR +G+ +G +G A
Sbjct: 183 TDFQAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATA 242
Query: 263 AAEGMLVT---MPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGS 319
+ + + +DA +A + + + Y +V +A A + G+
Sbjct: 243 EKASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAK--GA 300
Query: 320 DEPLALVKDL-KANGANTVIGPLNWD 344
+ +L K V G ++D
Sbjct: 301 KNSGEIKDNLAKTKDFEGVTGQTSFD 326
>4MS4-A nrPDB
Length = 420
Score = 165 bits (417), Expect = 3e-41, Method: Composition-based stats.
Identities = 72/369 (19%), Positives = 140/369 (37%), Gaps = 54/369 (14%)
Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGD-KLVGVEYDDACDPKQAVAV 84
+ + + MSG G A++D+N++ I D +L + +D CDP QA
Sbjct: 6 VYIGALFPMSGGWPG-GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKY 64
Query: 85 ANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAG 142
+++ ND IK ++ CSS + ++ ++++S G+++P L+ R + RT
Sbjct: 65 LYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHP 124
Query: 143 LDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGE 202
+ PT K + E ++IA I + +++ +K A + F
Sbjct: 125 SATLHNPTRVK-LFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSF---F 180
Query: 203 KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQ-----FMG--PEGVGNAS 255
D + + LK+++ + Y E ++ + L + +G +
Sbjct: 181 SDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIY 240
Query: 256 LSNIA------GDAAEGMLVTMPKRYDQDPAN---------QGIVDAL-KADKKDPSGPY 299
+I +A EG + T +PAN Q V+ L K K+ P
Sbjct: 241 DPSINCTVDEMTEAVEGHITTEI--VMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETG 298
Query: 300 VW----ITYAAVQSLATALERT-----------------GSDEPLALVKDLKANGANTVI 338
+ + Y A+ +LA AL +T + + + ++ V
Sbjct: 299 GFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS 358
Query: 339 GPLNWDEKG 347
G + +D G
Sbjct: 359 GHVVFDASG 367
>1QO0-A nrPDB
Length = 385
Score = 112 bits (279), Expect = 3e-25, Method: Composition-based stats.
Identities = 56/351 (15%), Positives = 121/351 (34%), Gaps = 12/351 (3%)
Query: 21 AMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQ 80
+ + + ++ + +G A + GA A++ +N +GG+ G + + D DP +
Sbjct: 3 SHQERPLIGLLFSETGVTADIERSQRYGALLAVEQLNREGGVGGRPIETLSQDPGGDPDR 62
Query: 81 AVAVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMR 139
A + N G+++++G S + + + E L+ P P +I+
Sbjct: 63 YRLCAEDFIRNRGVRFLVGCYMSHTRKAVMPVVERADALLCYP---TPYEGFEYSPNIVY 119
Query: 140 TAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGIT 199
+ A Y++ +R+ I Y ++ + V+ I
Sbjct: 120 GGPAPNQNSAPLAAYLIRHYG-ERVVFIGSDYIYPRESNHVMRHLYRQHGGTVLEEIYIP 178
Query: 200 A--GEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSV--GLKTQFMGPEGVGNAS 255
+ D + R+ + D V+ ++ R + + A
Sbjct: 179 LYPSDDDLQRAVERIYQARADVVFSTVVGTGTAELYRAIARRYGDGRRPPIASLTTSEAE 238
Query: 256 LSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALKADKKDPSGPYVW--ITYAAVQSLAT 312
++ + D AEG +V P D PA++ V A + + W Y L
Sbjct: 239 VAKMESDVAEGQVVVAPYFSSIDTPASRAFVQACHGFFPENATITAWAEAAYWQTLLLGR 298
Query: 313 ALERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADG 363
A + G+ + + L + GP+ + + + + + A G
Sbjct: 299 AAQAAGNWRVEDVQRHLYDIDIDAPQGPVRVERQNNHSRLSSRIAEIDARG 349
>3H5L-A nrPDB
Length = 419
Score = 104 bits (259), Expect = 7e-23, Method: Composition-based stats.
Identities = 63/344 (18%), Positives = 127/344 (36%), Gaps = 23/344 (6%)
Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAV 82
+D + + ++G +A G G + A +INA GGI G + V D V
Sbjct: 12 SDPVVIGCPAPLTGIVAADGIEFQRGIQMAADEINAVGGILGRPIELVFADTQSKGVDVV 71
Query: 83 -AVANKIVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMI--SPGATNPELTQRG---YQ 135
A ++++ D +I + D+ D G++ + + A + E+ + Y
Sbjct: 72 IQSAQRLIDRDNASALIAGYNLENGTALHDVAADAGVIAMHANTVAVHDEMVKSDPDRYW 131
Query: 136 HIMRTAGLDSSQGPTAAKYILE-------TVKPQRIAIIHDKQQYGEGLARSVQDGLKAA 188
+ ++ G K++ + + +IAII Y +A +++DG
Sbjct: 132 GTFQYDPPETLYGGGFLKFLKDIEDNGEFSRPNNKIAIITGPGIYSVNIANAIRDGAGEY 191
Query: 189 NANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYP-EMGQMLRQARSVGLKTQFMG 247
+V F+ + D+ +A+L+ + + +YP + + Q + +
Sbjct: 192 GYDVSLFETVAIPVSDWGPTLAKLRADPPAVIVVTHFYPQDQALFMNQFMTDPTNSLVYL 251
Query: 248 PEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKD-PSGPYVWITYAA 306
G A+ +IAGD + G+ QD A K D S TY+A
Sbjct: 252 QYGASLAAFRDIAGDNSVGVTYATVLGTLQDEMGDAFAKAYKERYGDLSSTASGCQTYSA 311
Query: 307 VQSLATALERT-------GSDEPLALVKDLKANGANTVIGPLNW 343
+ + + A + A+ L++ +G + +
Sbjct: 312 LYAYSIAAALAGGPGAPYDDVQNKAVADRLRSLIFRGPVGTMRF 355
>4F11-A nrPDB
Length = 433
Score = 81.4 bits (199), Expect = 6e-16, Method: Composition-based stats.
Identities = 33/184 (17%), Positives = 69/184 (37%), Gaps = 7/184 (3%)
Query: 40 QWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKY--VI 97
G AI+ I + ++ L YD CD + + + G + V
Sbjct: 31 SIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVF 90
Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQ-RGYQHIMRTAGLDSSQGPTAAKYIL 156
G +C S T ++ + ++ +S AT P L + Y + RT D++ P K +L
Sbjct: 91 GGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILK-LL 149
Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKEN 216
+ + +R+ + Q + + L + + + + D + +LK +
Sbjct: 150 KHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFS---NDPCTSVKKLKGND 206
Query: 217 IDFV 220
+ +
Sbjct: 207 VRII 210
>3LMK-A nrPDB
Length = 492
Score = 81.0 bits (198), Expect = 8e-16, Method: Composition-based stats.
Identities = 54/307 (17%), Positives = 107/307 (34%), Gaps = 46/307 (14%)
Query: 8 IIAGMIALAISHTAMADDI---KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKG 64
II G + ++ H D + K V Q+G ++ IN+ +
Sbjct: 22 IIIGAL-FSVHHQPTVDKVHERKCGAVRE------QYGIQRVEAMLHTLERINSDPTLLP 74
Query: 65 DKLVGVEYDDAC-----DPKQAVAVANKIV----------------------NDGIKYVI 97
+ +G E D+C +Q++ + I VI
Sbjct: 75 NITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVI 134
Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYIL 156
G SS ++ + I I+ AT+ +L+ + +++ MR D+ Q I+
Sbjct: 135 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVD-IV 193
Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFSALIARLKK 214
+ ++ +H + YGE + +D ++ I AGE+ F L+ +L
Sbjct: 194 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGISIAHSYKIYSNAGEQSFDKLLKKLTS 253
Query: 215 ENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNA-SLSNIAGDAAEGMLV 269
+ M +L R +GL + +G +G + +++ A G +
Sbjct: 254 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 313
Query: 270 TMPKRYD 276
+ D
Sbjct: 314 IKLQSPD 320
>6N4Y-A nrPDB
Length = 596
Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats.
Identities = 54/307 (17%), Positives = 106/307 (34%), Gaps = 46/307 (14%)
Query: 8 IIAGMIALAISHTAMADDI---KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKG 64
II G + ++ H D + K V Q+G ++ IN+ +
Sbjct: 52 IIIGAL-FSVHHQPTVDKVHERKCGAVRE------QYGIQRVEAMLHTLERINSDPTLLP 104
Query: 65 DKLVGVEYDDAC-----DPKQAVAVANKIV----------------------NDGIKYVI 97
+ +G E D+C +Q++ + I VI
Sbjct: 105 NITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVI 164
Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYIL 156
G SS ++ + I I+ AT+ +L+ + +++ MR D+ Q I+
Sbjct: 165 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVD-IV 223
Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFSALIARLKK 214
+ ++ +H + YGE + +D + I AGE+ F L+ +L
Sbjct: 224 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTS 283
Query: 215 ENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNA-SLSNIAGDAAEGMLV 269
+ M +L R +GL + +G +G + +++ A G +
Sbjct: 284 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 343
Query: 270 TMPKRYD 276
+ D
Sbjct: 344 IKLQSPD 350
>6N4X-A nrPDB
Length = 877
Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats.
Identities = 54/307 (17%), Positives = 106/307 (34%), Gaps = 46/307 (14%)
Query: 8 IIAGMIALAISHTAMADDI---KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKG 64
II G + ++ H D + K V Q+G ++ IN+ +
Sbjct: 41 IIIGAL-FSVHHQPTVDKVHERKCGAVRE------QYGIQRVEAMLHTLERINSDPTLLP 93
Query: 65 DKLVGVEYDDAC-----DPKQAVAVANKIV----------------------NDGIKYVI 97
+ +G E D+C +Q++ + I VI
Sbjct: 94 NITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVI 153
Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYIL 156
G SS ++ + I I+ AT+ +L+ + +++ MR D+ Q I+
Sbjct: 154 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVD-IV 212
Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFSALIARLKK 214
+ ++ +H + YGE + +D + I AGE+ F L+ +L
Sbjct: 213 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTS 272
Query: 215 ENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNA-SLSNIAGDAAEGMLV 269
+ M +L R +GL + +G +G + +++ A G +
Sbjct: 273 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 332
Query: 270 TMPKRYD 276
+ D
Sbjct: 333 IKLQSPD 339
>5X2M-A nrPDB
Length = 461
Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats.
Identities = 62/377 (16%), Positives = 137/377 (36%), Gaps = 62/377 (16%)
Query: 46 FNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKI--VNDGIK--------- 94
F R ++++IN + + +G + D C + K+ VND I+
Sbjct: 52 FQMMRFSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWEDASTGL 111
Query: 95 ----YVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRT-AGLDSSQG 148
V+G S+ + I+ M+S G + ++ Y +RT
Sbjct: 112 PNAIGVVGPFTSTHALSIAPIFMTNLFPMVSYGCSGSVFSKENLYPSFLRTVHSNKDVIN 171
Query: 149 PTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSAL 208
+ + +A ++ +G+ ++ ++ + + F+ I D+ +
Sbjct: 172 AIVGIIL--NFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSEICLAFYKAINVN-TDYLQV 228
Query: 209 IARLKKENIDFV--YYGGYYPEMGQMLRQARSVGLKTQF-MGPEGVG-NASLSNIAGDAA 264
+++++NI + + Y E ++ A + + + + +G N L ++ G
Sbjct: 229 FKQIEEQNIKVIVVFAPKVYAEA--VVESAVQLNVTNKVWIADDGWSLNKKLPSMNGIQN 286
Query: 265 EGMLVTMPKRYDQDPANQGIVDAL--KADKKDPSG-----------------------PY 299
G ++ + + P + + + D D +
Sbjct: 287 IGTVLGVAQPVVTIPGFTDFIYSAISQTDGGDTEQKMFCNQKCNCSNLSVKSLLNADPSF 346
Query: 300 VWITYAAVQSLATALE---RTGSD--------EPLALVKDLKANGANTVIGPLNWDEKGD 348
+ YAAV ++A AL R GSD P ++++LK + + + +DE GD
Sbjct: 347 SFPVYAAVYAIAHALHNTLRCGSDRCPKNITVHPHMILEELKKSNFTLLNQTVQFDENGD 406
Query: 349 LKGFDFGVFQWHADGSS 365
K V W++ G++
Sbjct: 407 PKFGSLSVVFWNSSGNA 423
>6BT5-A nrPDB
Length = 479
Score = 76.8 bits (187), Expect = 1e-14, Method: Composition-based stats.
Identities = 76/417 (18%), Positives = 132/417 (31%), Gaps = 91/417 (21%)
Query: 42 GDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACD-----PKQAVAVANKIVN------ 90
G AI IN + + +GV D C +Q++ ++
Sbjct: 36 GIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDV 95
Query: 91 -------------DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQH 136
D I VIG SS + ++I I IS +T PEL+ Y
Sbjct: 96 KCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDF 155
Query: 137 IMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKA-ANANVVFF 195
R DS Q I+ + ++ + + YGE + + ++
Sbjct: 156 FSRVVPPDSYQAQAMVD-IVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVSIAQS 214
Query: 196 DGITAGEK--DFSALIAR-LKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQF--MGPEG 250
I + +F +I R L+ N V ++ ++L A+ + F +G +
Sbjct: 215 QKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDS 274
Query: 251 VGNASLSN-IAGDAAEGMLVTMPKRYDQDPANQGI------------------------- 284
G+ + AEG + +PKR D ++
Sbjct: 275 WGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCK 334
Query: 285 ----------------VDALKADKKDPSGPYVWITYAAVQSLATALE------------- 315
++ + D V AV S+A AL
Sbjct: 335 LGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGL 394
Query: 316 --RTGSDEPLALVKDLKANGANTVIG-PLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369
R + + L+ ++A N G P+ ++E GD G + +FQ+ ST K
Sbjct: 395 CPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYK 450
>1ISS-A nrPDB
Length = 490
Score = 74.8 bits (182), Expect = 5e-14, Method: Composition-based stats.
Identities = 35/173 (20%), Positives = 69/173 (39%), Gaps = 8/173 (4%)
Query: 90 NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQG 148
I VIG SS ++ + I I+ AT+ +L+ + Y++ +R D+ Q
Sbjct: 121 KKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQA 180
Query: 149 PTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFS 206
I++ ++ +H + YGE + ++ + D I AGEK F
Sbjct: 181 RAMLD-IVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFD 239
Query: 207 ALIARLKKENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNAS 255
L+ +L++ + M +L R +G+ + +G +G +
Sbjct: 240 RLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRD 292
>5C5C-A nrPDB
Length = 481
Score = 74.5 bits (181), Expect = 7e-14, Method: Composition-based stats.
Identities = 54/269 (20%), Positives = 94/269 (34%), Gaps = 35/269 (13%)
Query: 42 GDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACD-----PKQAVAVANKIVN------ 90
G A+ IN+ + + +G D C +Q++ ++
Sbjct: 43 GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDV 102
Query: 91 -------------DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELT-QRGYQH 136
+ + VIG SS + ++I I IS +T PEL+ R Y
Sbjct: 103 RCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDF 162
Query: 137 IMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYG-EGLARSVQDGLKAANANVVFF 195
R DS Q I++ + ++ + + YG +G+ Q +A ++
Sbjct: 163 FSRVVPPDSFQAQAMVD-IVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLSIAQS 221
Query: 196 DGITAGEK----DFSALIARLKKE-NIDFVYYGGYYPEMGQMLRQARSVGLKTQF--MGP 248
I K DF +I +L N V ++ Q+L A+ F +G
Sbjct: 222 VRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGS 281
Query: 249 EGVGNASLS-NIAGDAAEGMLVTMPKRYD 276
+ G+ + D AEG + PKR
Sbjct: 282 DSWGSKINPLHQHEDIAEGAITIQPKRAT 310
>4M88-A nrPDB
Length = 357
Score = 64.1 bits (154), Expect = 8e-11, Method: Composition-based stats.
Identities = 49/320 (15%), Positives = 105/320 (32%), Gaps = 13/320 (4%)
Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVA 85
I + +G +GP+A G + + N GGI+G KL E DD +
Sbjct: 5 IVLGQIGPFTGPLAADAAGLNQGIKAYLAQANKAGGIRGQKLTLFEADDRFSGEGFAEQF 64
Query: 86 NKIVNDGIKYVIGHLCSSSTQPASD--IYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143
K + +I + S++ + D + + +++++ L G+
Sbjct: 65 PKAMEKKPLALISPMGSAAIKRMLDDKLLDTAPVVVVNGVPGAESLRTPGHPKFFHVRAG 124
Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAG-- 201
D + + + + ++A ++ G VQ+ +K + +G+ +G
Sbjct: 125 DKQEIEEIVSH-AQMLGMSKLATLYQDLPTGTSGMAVVQEAVKTVPGGKIELNGVKSGPD 183
Query: 202 EKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAG 261
+A ++ V G P + + R + V A + + G
Sbjct: 184 AAALAAAARQIAALGAQGVLVIGPPPFIVAGIAALRKADVTQPLFVLSYVSAAQIVKVVG 243
Query: 262 DAAEGMLVTMPKRYDQD----PANQGIVDALKADKKDPS--GPYVWITYAAVQSLATALE 315
A + + D + P + A+K + Y + +++ AL+
Sbjct: 244 VAGARGVGIVQAFPDPNDKMLPVQREFQAAMKEAFPQMQEYTEFQLEGYLSARTVGEALK 303
Query: 316 --RTGSDEPLALVKDLKANG 333
+ L L G
Sbjct: 304 HPKNTGLSAANLAATLSTMG 323
>5X2N-B nrPDB
Length = 478
Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats.
Identities = 58/379 (15%), Positives = 111/379 (29%), Gaps = 76/379 (20%)
Query: 42 GDMEFNGARQAIKDINAKGGIKGD-KLVGVEYDDACDPKQAVAVANKIVNDG-------- 92
G + A+++INA + KL Y+ V A + +
Sbjct: 53 GLGRALVMKYAVEEINANSQLLPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVE 112
Query: 93 ---------IKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQR-GYQHIMRTAG 142
+ VIG S + + IS GAT+ + + Y RT
Sbjct: 113 CNYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLVYPSFFRTVP 172
Query: 143 LDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGE 202
D Q + +++ +A++ +++YG+ + + V + G+
Sbjct: 173 SDIRQVDAMVQ-LIKKFNWNWVAVVGSEEEYGQQGVQQFSKKAEDMGV-CVAYQGLIPIY 230
Query: 203 KDFSALIA----RLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNA---- 254
D I ++ + V + L ++ +
Sbjct: 231 DDPKPAIQTIINNIQTTEVKVVVVFSLVSPAVSFFEEVIKKNLTGVWIASSSWAISDKVY 290
Query: 255 SLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDAL------KADKKDPSGPY--------- 299
SL NI + G ++ + + L + + P PY
Sbjct: 291 SLPNID---SIGTVIGFIDETETLELLSPFTEVLFKKIHEASPTEKPEDPYNPCPECWSL 347
Query: 300 ----------------VWITYAAVQSLATALER-----------TGSDE--PLALVKDLK 330
+ YAAV ++A AL + + S P L++ LK
Sbjct: 348 SPANVSLVKEESVQRTAFSVYAAVYTVAHALHKLLECNSAACKWSSSTRLYPWKLLEVLK 407
Query: 331 ANGANTVIGPLNWDEKGDL 349
N L +D+ G+
Sbjct: 408 EFSVNISNTSLKFDQNGNP 426
>1YK0-A nrPDB
Length = 480
Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats.
Identities = 21/161 (13%), Positives = 53/161 (32%), Gaps = 9/161 (5%)
Query: 64 GDKLVGVEYDDACDPKQAVAVANKIVND-GIK--YVIGHLCSSSTQPASDIYEDEGILMI 120
G + D C + ++ +++ G K ++G +C + P + + + M+
Sbjct: 96 GTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPML 155
Query: 121 SPGATNPELTQR--GYQHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEG-- 176
S GA + Y H+ R A + G + R A+++ +
Sbjct: 156 SAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLA-LFRHHHWSRAALVYSDDKLERNCY 214
Query: 177 -LARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKEN 216
V + + + + + D ++ ++
Sbjct: 215 FTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASE 255
>2YFH-A nrPDB
Length = 448
Score = 36.3 bits (82), Expect = 0.023, Method: Composition-based stats.
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 82 VAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTA 141
V A++++ +G+K V +T A+++++ G+L A N + T+
Sbjct: 328 VDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAG--------GVATS 379
Query: 142 GLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLK-AANANVVFFDGI 198
GL+ +Q + E V + I+ D A G A AN+V F I
Sbjct: 380 GLEMAQNAARLGWKAEKVDARLHHIMTDIHDGSAAAAERYGLGYNLVAGANIVGFQKI 437
>5L2E-A nrPDB
Length = 688
Score = 35.6 bits (80), Expect = 0.033, Method: Composition-based stats.
Identities = 52/351 (14%), Positives = 107/351 (30%), Gaps = 55/351 (15%)
Query: 49 ARQAIKDINAKGGI-KGDKLVG-VEYDDACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQ 106
R A+ D+N I + +K+ V + D +P QAV A +++N GI ++ + +S
Sbjct: 23 FRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAG 82
Query: 107 PASDIYEDEGILMI---SPGATNP----ELT--QRGYQHIMRTAGLDSSQGPTAAKYILE 157
+ + I + A P LT R + + ++
Sbjct: 83 SLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLNEVIL--RVVT 140
Query: 158 TVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENI 217
Q+ I +D +Y + D + +V K + L ++ E +
Sbjct: 141 EYAWQKFIIFYDS-EYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEEL 199
Query: 218 ----DFV---YYGGYYPEMGQMLRQARSVGLKTQ----FMGPEGVGNASLSNIAGDA-AE 265
D + + + L + E + + + + +
Sbjct: 200 NRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGR 259
Query: 266 GMLVTMPKRYDQDPANQGIVDALKADKK--DPSGPYV-------WITYAAVQSLATALER 316
++ Q+ + + + DP P+ Y V LA A +
Sbjct: 260 LTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEISNLYIYDTVLLLANAFHK 319
Query: 317 TGSDEP--------------------LALVKDLKANGANTVIGPLNWDEKG 347
D ++++ +K G N + G L + E G
Sbjct: 320 KLQDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVNGLTGDLEFGENG 370
>3NV9-A nrPDB
Length = 487
Score = 33.6 bits (75), Expect = 0.16, Method: Composition-based stats.
Identities = 16/54 (29%), Positives = 26/54 (48%)
Query: 43 DMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV 96
D A +A+ + K GI D ++G + PK+A VA + + DG+ V
Sbjct: 380 DNMAIAASRALAEFAEKRGINPDNIIGTMDEPGIFPKEAADVAMQAIKDGVARV 433
>4FHN-X nrPDB
Length = 450
Score = 32.1 bits (71), Expect = 0.39, Method: Composition-based stats.
Identities = 17/81 (20%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 82 VAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTA 141
V A++++ +G+K V +T A+++++ G+L A N + T+
Sbjct: 332 VDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAG--------GVATS 383
Query: 142 GLDSSQGPTAAKYILETVKPQ 162
GL+ +Q + E V +
Sbjct: 384 GLEMAQNAARLGWKAEKVDAR 404
>4ZTY-A nrPDB
Length = 769
Score = 30.9 bits (68), Expect = 1.00, Method: Composition-based stats.
Identities = 16/47 (34%), Positives = 24/47 (51%)
Query: 288 LKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA 334
L ++KK PS Y W ++A + A EP A+ +L+AN A
Sbjct: 340 LASEKKLPSDVYEWFSFAVEKVKEVATLAKAVTEPEAVKAELEANAA 386
>3E8L-C nrPDB
Length = 185
Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats.
Identities = 16/77 (20%), Positives = 26/77 (33%)
Query: 246 MGPEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYA 305
MG + + + GDA + L Y A G L +KD YV+
Sbjct: 1 MGHHHHHHMPVVDSDGDAVQLNLGGNYPLYTIQSAAIGFRGGLSTLRKDACKSYVYEAPE 60
Query: 306 AVQSLATALERTGSDEP 322
+ L + + +P
Sbjct: 61 TDRGLPVGFSASATSQP 77
>3WWM-A nrPDB
Length = 269
Score = 30.2 bits (66), Expect = 1.6, Method: Composition-based stats.
Identities = 22/145 (15%), Positives = 46/145 (31%), Gaps = 10/145 (6%)
Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144
A + +G+K ++ H S+ T ++ + PG LT R I
Sbjct: 21 AASLWKEGVKLLLVHGGSAETNKVAEALGHPPRFLTHPGGQVSRLTDRKTLEIFEMVYCG 80
Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204
+L+ I + + G ++ ++ V D
Sbjct: 81 LVNKRLV--ELLQKEGANAIGLSGLDGRLFVGRRKTAVKYVENGKVKV--------HRGD 130
Query: 205 FSALIARLKKENIDFVYYGGYYPEM 229
++ + + K +D + GY P +
Sbjct: 131 YTGTVEEVNKALLDLLLQAGYLPVL 155
>4P98-A nrPDB
Length = 317
Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats.
Identities = 32/202 (15%), Positives = 66/202 (32%), Gaps = 7/202 (3%)
Query: 76 CDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQ 135
DP QA V + G V+GH ++P + + + A+
Sbjct: 59 ADPTQAEPVIRQFAARGFDLVVGHGID-VSEPILRVATE--FPDVHFSASGDATLAERLP 115
Query: 136 HIMRTAGLDSSQGPTAAKYILETV-KPQRIAII-HDKQQYGEGLARSVQDGLKAANANVV 193
+ D Q ++ ++ +++ + + + + ++ GLKAAN
Sbjct: 116 PNVDGWTYDFGQLGYLDGFVAGSLRGVEKVGAVGGPQLPFVLATHKGIRAGLKAANPRAS 175
Query: 194 FFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGN 253
+ + T D + +D + G+ L QA G +G
Sbjct: 176 YEETYTGRFYDLQKEQEAARGL-LDKGAQLLVATDDGRGLGQAAVAG-DVPTIGVSAAAG 233
Query: 254 ASLSNIAGDAAEGMLVTMPKRY 275
A + + A+ L+ + Y
Sbjct: 234 ADIKAVNITTAKLDLLPTYQSY 255
>4KWT-A nrPDB
Length = 358
Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats.
Identities = 26/140 (18%), Positives = 44/140 (31%), Gaps = 26/140 (18%)
Query: 27 KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVAN 86
K+ + + GP A W D E A QAI G K+
Sbjct: 204 KMGMDIRLVGPQAYWPDEELVAACQAIAK------QTGGKITL----------------T 241
Query: 87 KIVNDGIKYVIGHLCSS-STQPASDIYEDEGILMISPGATN-PELTQRGYQHIMRTAGLD 144
+ V +G++ + S DE + ++ P N L Q G ++ L
Sbjct: 242 ENVAEGVQGCDFLYTDVWVSMGESPEAWDERVALMKPYQVNMNVLKQTGNPNVKFMHCLP 301
Query: 145 SSQG--PTAAKYILETVKPQ 162
+ T K + + +
Sbjct: 302 AFHNDETTIGKQVADKFGMK 321
>3MW8-A nrPDB
Length = 240
Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats.
Identities = 28/149 (18%), Positives = 53/149 (35%), Gaps = 12/149 (8%)
Query: 80 QAVAVANKIVND--GIKYVIGHLCSSSTQPASDIYEDE--GILMISPGATNPELTQRGYQ 135
+A AV +++ +I S+ + + + AT L +G
Sbjct: 36 EAAAVTQAQLDELSRADILIFISTSAVSFATPWLKDQWPKATYYAVGDATADALALQG-I 94
Query: 136 HIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFF 195
R+ + LE V ++I I+ G+G ++ DGL+ ANV +
Sbjct: 95 TAERSPADSQATEGLLTLPSLEQVSGKQIVIVR-----GKGGREAMADGLRLRGANVSYL 149
Query: 196 DGITAGEK--DFSALIARLKKENIDFVYY 222
+ D A ++R + ID +
Sbjct: 150 EVYQRACPPLDAPASVSRWQSFGIDTIVV 178
>3DAF-A nrPDB
Length = 358
Score = 28.2 bits (61), Expect = 6.6, Method: Composition-based stats.
Identities = 16/86 (18%), Positives = 28/86 (32%), Gaps = 3/86 (3%)
Query: 138 MRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDG 197
RT A + + V IA+ H YG L V D + ++ F +
Sbjct: 11 YRTHAAAGITNFMRACEVAKEVGKPEIALTHSSITYGAELLHLVPDVKEVIVSDPCFAEE 70
Query: 198 ---ITAGEKDFSALIARLKKENIDFV 220
+ E D ++ N + +
Sbjct: 71 PGLVVIDEFDPKEVMEAHLSGNPESI 96
>3CPT-A nrPDB
Length = 143
Score = 27.9 bits (60), Expect = 6.9, Method: Composition-based stats.
Identities = 12/71 (16%), Positives = 22/71 (30%)
Query: 173 YGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQM 232
Y +G A ++ L +V I ++D +I + G+
Sbjct: 16 YFQGSADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALA 75
Query: 233 LRQARSVGLKT 243
Q +GL
Sbjct: 76 TDQGSKLGLSK 86
>4AQ4-A nrPDB
Length = 419
Score = 27.9 bits (60), Expect = 8.0, Method: Composition-based stats.
Identities = 28/175 (16%), Positives = 58/175 (33%), Gaps = 17/175 (9%)
Query: 56 INAKGGIKGDKL-VGVEYDDACDPKQAVAVANKI-VNDGIKYVIGHLCSSSTQPASDIYE 113
++ G G ++ + +A +P + K + I + + +YE
Sbjct: 11 WHSMEGELGKEVDSLAQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYE 70
Query: 114 DEGILMISPGATNPELTQRGYQHIMRTAG--LDSSQG-PTAAKYILETVKPQRIAIIHDK 170
M++ A P + + AG D SQ PT + Y ++ ++
Sbjct: 71 VGTATMMASKAIKPV------YDVFKEAGIQFDESQFVPTVSGYYSDSKTGH---LLSQP 121
Query: 171 QQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGY 225
+ +D K A + + +D + A+LK + Y G+
Sbjct: 122 FNSSTPVLYYNKDAFKKAGLDP---EQPPKTWQDLADYAAKLKASGMKCGYASGW 173
>3S99-A nrPDB
Length = 356
Score = 27.5 bits (59), Expect = 9.3, Method: Composition-based stats.
Identities = 10/52 (19%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
Query: 66 KLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGI 117
++ + + DP + A +++ G+ + H S A + D GI
Sbjct: 182 RVKVIWVNSWFDPGKEADAAKALIDQGVDIITQHTDS---TAAIQVAHDRGI 230
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.306 0.122 0.281
Lambda K H
0.267 0.0375 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,415,210
Number of Sequences: 36641
Number of extensions: 426280
Number of successful extensions: 5062
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 4897
Number of HSP's gapped (non-prelim): 178
length of query: 369
length of database: 10,336,785
effective HSP length: 98
effective length of query: 271
effective length of database: 6,745,967
effective search space: 1828157057
effective search space used: 1828157057
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 59 (27.5 bits)