BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04816 (369 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1USI-A nrPDB 707 0.0 1Z15-A nrPDB 568 e-163 4QWV-A nrPDB 449 e-126 4N0Q-A nrPDB 254 5e-68 3IP9-A nrPDB 247 7e-66 4MLC-A nrPDB 124 5e-29 4GNR-A nrPDB 99 3e-21 4MPT-A nrPDB 74 1e-13 3I45-A nrPDB 67 2e-11 4XFK-A nrPDB 61 1e-09 4MS4-A nrPDB 51 8e-07 4EVS-A nrPDB 47 1e-05 4F06-A nrPDB 45 4e-05 4F11-A nrPDB 38 0.009 1QO0-A nrPDB 34 0.13 3H5L-A nrPDB 33 0.15 5X2M-A nrPDB 33 0.20 3CPG-A nrPDB 30 1.7 3WCZ-A nrPDB 30 1.9 2PCL-A nrPDB 30 2.0 3K4W-A nrPDB 29 3.0 2OV1-A nrPDB 29 3.2 1PQ4-A nrPDB 29 3.6 4ZTY-A nrPDB 29 3.9 3ILS-A nrPDB 28 4.6 4M88-A nrPDB 28 9.3 1RK6-A nrPDB 27 9.6 >1USI-A nrPDB Length = 346 Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/346 (99%), Positives = 345/346 (99%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA Sbjct: 1 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 60 Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL Sbjct: 61 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 120 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK Sbjct: 121 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 180 Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA Sbjct: 181 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 240 Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL Sbjct: 241 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 300 Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSST AK Sbjct: 301 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTKAK 346 >1Z15-A nrPDB Length = 344 Score = 568 bits (1465), Expect = e-163, Method: Compositional matrix adjust. Identities = 273/346 (78%), Positives = 305/346 (88%), Gaps = 2/346 (0%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83 +DIKVAVVGAMSGP+AQ+GD EF GA QA+ DINAKGGIKG+KL V+YDDACDPKQAVA Sbjct: 1 EDIKVAVVGAMSGPVAQYGDQEFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVA 60 Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 VANK+VNDGIKYVIGHLCSSSTQPASDIYEDEGILMI+P AT PELT RGYQ I+RT GL Sbjct: 61 VANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGL 120 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203 DS QGPTAAKYILE VKPQRIAI+HDKQQYGEGLAR+VQDGLK NANVVFFDGITAGEK Sbjct: 121 DSDQGPTAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEK 180 Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263 DFS L+ARLKKENIDFVYYGGY+PEMGQ+LRQAR+ GLKTQFMGPEGV N SLSNIAG++ Sbjct: 181 DFSTLVARLKKENIDFVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGES 240 Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323 AEG+LVT PK YDQ PAN+ IVDA+KA K+DPSG +VW TYAA+QSL L + SD+P Sbjct: 241 AEGLLVTKPKNYDQVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQ--SDDPA 298 Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369 + K LKAN +TV+GPL WDEKGDLKGF+FGVF WHA+G++T AK Sbjct: 299 EIAKYLKANSVDTVMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK 344 >4QWV-A nrPDB Length = 321 Score = 449 bits (1155), Expect = e-126, Method: Compositional matrix adjust. Identities = 239/337 (70%), Positives = 258/337 (76%), Gaps = 26/337 (7%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA Sbjct: 2 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 61 Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL Sbjct: 62 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 121 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGIT---- 199 DSSQGPTAAKYILETVKPQR+ I+ D AA ++ D IT Sbjct: 122 DSSQGPTAAKYILETVKPQRVLIVDD-----------------AAFMRMMLKDIITKAGY 164 Query: 200 --AGE-KDFSALIARLKKENIDFVYYGGYYPEMGQM--LRQARSVGLKTQFMGPEGVGNA 254 AGE + + + K+ D V PEM + +++ + + + +G Sbjct: 165 EVAGEATNGREAVEKYKELKPDIVTMDITMPEMNGIDAIKEIMKIDPNAKIIVCSAMGQQ 224 Query: 255 SLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATAL 314 ++ A A + PKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATAL Sbjct: 225 AMVIEAIKAGAKDFIVKPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATAL 284 Query: 315 ERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKG 351 ERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKG Sbjct: 285 ERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKG 321 >4N0Q-A nrPDB Length = 354 Score = 254 bits (648), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 134/337 (39%), Positives = 199/337 (59%), Gaps = 3/337 (0%) Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84 DI + V+ ++GP+A +GD GA A++ IN GGIKG+K+V DDA +PKQ V+ Sbjct: 10 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSA 69 Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144 AN+IV DGIK+V+G + + P SD+ + G+LM++P AT P+LT RG +++ RT G D Sbjct: 70 ANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRD 129 Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204 Q A Y+L+ +K +++A+IHDK YG+GLA + + + V +D +T G+KD Sbjct: 130 GQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKD 189 Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264 FSAL+ +LK + VY+GGY+ E G + RQ G++ +G EG+ N I G A Sbjct: 190 FSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNA 249 Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGS-DEPL 323 +G L T K ++PA + + ALKA K P+ + YAAV+ + +ER GS D+ Sbjct: 250 QGTLFTNAKDATKNPAAKDAIQALKA-KNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSA 308 Query: 324 ALVKDLK-ANGANTVIGPLNWDEKGDLKGFDFGVFQW 359 A+ K L T IG L + E GDL F +F+W Sbjct: 309 AVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKW 345 >3IP9-A nrPDB Length = 356 Score = 247 bits (630), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 139/335 (41%), Positives = 205/335 (61%), Gaps = 1/335 (0%) Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84 D+ +AV ++GP A +G GA QA KDINA GGI G+++ V DD DPKQ ++V Sbjct: 2 DVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQGISV 61 Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144 ANK V DG+K+V+GH S + PAS++Y + GIL I+P ATNP T+RG + RT G D Sbjct: 62 ANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRD 121 Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204 QG A KY+ + K ++AIIHDK YG+GLA + AA V ++G+ G+KD Sbjct: 122 DQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKD 181 Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264 FSALI+++K+ + +Y+GG + E G ++RQA GLK + + +G+ + L++IAGDA Sbjct: 182 FSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAKLVSGDGIVSNELASIAGDAV 241 Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLA 324 EG L T P N+ +V+ KA +P Y +YAA+Q++A A + GS EP Sbjct: 242 EGTLNTFGPDPTLRPENKELVEKFKAAGFNPEA-YTLYSYAAMQAIAGAAKAAGSVEPEK 300 Query: 325 LVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQW 359 + + LK T +G +++DEKGD K + +++W Sbjct: 301 VAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEW 335 >4MLC-A nrPDB Length = 356 Score = 124 bits (312), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 100/322 (31%), Positives = 155/322 (48%), Gaps = 14/322 (4%) Query: 37 PIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIV-NDGIKY 95 P A D+ G A+++IN +GG++G KL V+ DD + ++ +A+A N GI+ Sbjct: 18 PFASLDDLFAEGLELAVQEINEQGGVQGRKLSLVKADDEAELEKGLAIAQAFADNAGIQA 77 Query: 96 VIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYI 155 VIGH S + PA+ IY+ G++M+SP +T+P+LT GY H+ R D A Y+ Sbjct: 78 VIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDHGYIHVFRNIPSDQEIARQLAIYL 137 Query: 156 LETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKE 215 E +R+ I + YG GLA + +D +A +V KD L + + Sbjct: 138 AEQ-GHERMVIYYTDDSYGNGLANAFEDYARAQGITIVDRFNYYGNLKDLERLYDKWQAF 196 Query: 216 NIDFVYYGGYYPEMG-QMLRQARSVGLKTQFMGPEGVGNASLS----NIAGDAAEGMLV- 269 +D ++ G + L A+SVG++ + SL+ NI G AEG+LV Sbjct: 197 GMDGIFIAKTATGGGTEFLVDAKSVGIEVPLIAGNSWDALSLTEDIENI-GMTAEGLLVG 255 Query: 270 --TMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVK 327 P+R D Q V+A + + P Y Y AV LA ALE++ P L + Sbjct: 256 SFFNPQR--PDSRTQDFVEAFRREYGQPPTSYAAAGYDAVILLAEALEKSDLTHPATLAQ 313 Query: 328 DLKANGA-NTVIGPLNWDEKGD 348 L+ G V+G +D +GD Sbjct: 314 GLRDLGPWEGVMGMHRFDGRGD 335 >4GNR-A nrPDB Length = 353 Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 67/227 (29%), Positives = 117/227 (51%), Gaps = 6/227 (2%) Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVA 85 IK+ SG +A +G E GA+ A+ +INA GGI G ++ V+ D+ + +A +V Sbjct: 8 IKIGFNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVT 67 Query: 86 NKIVNDG-IKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144 +V + V+G S +T A G+ +ISP AT LT +G ++ D Sbjct: 68 TNLVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLT-KGQDYLFIGTFQD 126 Query: 145 SSQGPTAAKYILETVKPQRIAIIHDK-QQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203 S QG + Y+ E + +++ + D Y +G+A+S ++ K +V + AG+ Sbjct: 127 SFQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKG---EIVADETFVAGDT 183 Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEG 250 DF A + ++K ++ D + GYY E G+++ QAR +G+ +G +G Sbjct: 184 DFQAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDG 230 >4MPT-A nrPDB Length = 380 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 39/347 (11%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKL-VGVEYDDACDPKQA 81 AD IK+ + A++GP ++G+ A++ NAKGGI G K+ + + DD +P +A Sbjct: 4 ADTIKIGMTSALTGPYNEFGEGNRRAVELAVEQWNAKGGINGKKIEIAMLLDDQLNPDRA 63 Query: 82 VAVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQ----- 135 V I+ N I +IG S D+ + +G ++P A P +T G + Sbjct: 64 VQNIRAILDNKDIVGIIGPAGSGPMLAVIDMVQADGRPYMNPIAQTPVVTYPGEKTGEKP 123 Query: 136 --HIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYG----EGLARSVQDGLKAAN 189 ++ A + + +Y+ + K R+ IIH+ YG + LA S+ K Sbjct: 124 RPNVFSFALQNDIEAVAMGEYLAKKFK--RVGIIHESTAYGVTGVDYLAASIA---KNGG 178 Query: 190 ANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPE 249 A V D G +D +A +AR+K+ N+D + G ++ + R + + Sbjct: 179 AKPVATDSYNQGAQDMTAQVARMKRANVDAIAAIGLGKDLAVLRRTMARLNVNVPLAASN 238 Query: 250 GVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADK----------KDPSGPY 299 G AG+ G L TM + +P D KA K DP P Sbjct: 239 GALGQPYQEGAGELTLGTLGTMIGAFG-NPMRAPAADFAKAYKAKYGTDRWWGNDPENPQ 297 Query: 300 VWIT------YAAVQSLATALERTGSDEPLALVKDLKA----NGANT 336 +++ Y A L + S +P A++ +++ G NT Sbjct: 298 LFMAISVSNGYDAANILFEGIRLANSTDPKAVIAAIESIKDYQGVNT 344 >3I45-A nrPDB Length = 387 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 80/309 (25%), Positives = 139/309 (44%), Gaps = 19/309 (6%) Query: 47 NGARQAIKDINAKGGIKGDK-LVGVEYDDACDPKQAVAVANKIVN-DGIKYVIGHLCSSS 104 NG + A++ INA GG+ G + L + DD DP +AV A +++ G+ + G S Sbjct: 26 NGWQLAVEQINAAGGLLGGRPLEVISRDDGGDPGKAVTAAQELLTRHGVHALAGTFLSHV 85 Query: 105 TQPASDIYEDEGILMISPGATNPELT-QRGYQHIMRTAGLDSSQGPTAAKYILETVKPQR 163 SD +L ++ LT ++G ++ R Q A + + R Sbjct: 86 GLAVSDFARQRKVLFMASEPLTDALTWEKGNRYTYRLRPSTYMQAAMLAAEAAK-LPITR 144 Query: 164 IAIIHDKQQYGEGLARSVQDGLKAANANVVFF-DGITAGEK-DFSALIARLKKENIDFVY 221 A I +YG+ ++ L AA V F + A K D + L++ + ++ Sbjct: 145 WATIAPNYEYGQSAVARFKELLLAARPEVTFVAEQWPALYKLDAGPTVQALQQAEPEGLF 204 Query: 222 YGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNAS-----LSNIAGDAAEGMLVTMPKRYD 276 + ++ + +R+ R GL F G + V + L+ + +A EG +VT YD Sbjct: 205 NVLFGADLPKFVREGRVRGL---FAGRQVVSMLTGEPEYLNPLKDEAPEGWIVTGYPWYD 261 Query: 277 QDPA-NQGIVDALKADKKDPSGPYV--WITYAAVQSLATALERTGSDEPLALVKDLKANG 333 D A ++ V+A +A K+ P+V + Y + ++A A E+ G E LV+ LK Sbjct: 262 IDTAPHRAFVEAYRARWKE--DPFVGSLVGYNTLTAMAVAFEKAGGTESETLVETLKDMA 319 Query: 334 ANTVIGPLN 342 +T +GPL+ Sbjct: 320 FSTPMGPLS 328 >4XFK-A nrPDB Length = 399 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 82/320 (25%), Positives = 143/320 (44%), Gaps = 41/320 (12%) Query: 15 LAISHTAMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDD 74 +A H A+ +K+A+V +SGP A G + + IN GG G+K+ +EYD+ Sbjct: 1 MAHHHHHHAEPLKIALVETLSGPQASTGLLYRAAVLYQLGKINEAGGFNGEKIQILEYDN 60 Query: 75 ACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYED----------EGILMISPGA 124 P A + DG + ++ SS+ A I ED + +L ++ GA Sbjct: 61 QGGPVGAADRVKAAIADGAQIIV---QGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGA 117 Query: 125 TNPELT-QRGYQHIMRTAGLDSSQGPTAAKYILET-VKPQRIAIIHDKQQYGEGLARSVQ 182 ELT + + + R + + + T A+ + + + +R I+ +G + +V Sbjct: 118 EALELTGSKCHFYHFRFSPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTV- 176 Query: 183 DGLKAANANVVFFDGI--TAGE----KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQA 236 ANA + ++ + T E +DFS +A+++ N+D V+ G + ++ +++ A Sbjct: 177 ----VANAKEIGYEVVDKTLHEVNKIQDFSPYVAKIQAANVDTVFTGNWSNDLLLLMKAA 232 Query: 237 RSVGLKTQFMG-----PEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKAD 291 GLK +F P +GN AG AEG +V+ P + AN A D Sbjct: 233 SGAGLKAKFATSFLDQPGNIGN------AGAIAEGHIVSTPFNPE---ANGEASMAFAED 283 Query: 292 KKDPSGPY-VWITYAAVQSL 310 K +G Y ++ AAV L Sbjct: 284 YKKVTGHYPSYVEPAAVFGL 303 >4MS4-A nrPDB Length = 420 Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 36/146 (24%), Positives = 71/146 (48%), Gaps = 4/146 (2%) Query: 52 AIKDINAKGGIKGD-KLVGVEYDDACDPKQAVAVANKIV-NDGIKYVIGHLCSSSTQPAS 109 A++D+N++ I D +L + +D CDP QA +++ ND IK ++ CSS + + Sbjct: 31 ALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVA 90 Query: 110 DIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIH 168 + ++++S G+++P L+ R + RT + PT K + E ++IA I Sbjct: 91 EAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVK-LFEKWGWKKIATIQ 149 Query: 169 DKQQYGEGLARSVQDGLKAANANVVF 194 + +++ +K A + F Sbjct: 150 QTTEVFTSTLDDLEERVKEAGIEITF 175 >4EVS-A nrPDB Length = 371 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 70/281 (24%), Positives = 123/281 (43%), Gaps = 25/281 (8%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIK-GDKLVGVEYDDAC--DPK 79 AD IKV V+G MSGP A +G + I A+ G K G V Y D +P Sbjct: 3 ADTIKVGVIGTMSGPYALFG----QNFKMGIDAWVAEHGNKVGGHTVEFVYRDEVSPNPA 58 Query: 80 QAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIM 138 Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ +I+ Sbjct: 59 QSKALAQELIVKEKVQYIAGLYFTPNAMAVAPLLQEAKVPMVVLNAATSSITEKS-PYIV 117 Query: 139 RTAGLDSSQGPTAAKYILETVKPQRIAI-IHDKQQYGEGL--ARSVQDGLKAANANVVFF 195 RT+ Q A + + +++AI + D YG G+ + + +A +VV Sbjct: 118 RTS-FTMFQNTVPAAKVAKQKGAKKVAIAVSD---YGPGIDAETAFKKTFEAEGGSVVEA 173 Query: 196 DGITAGEKDFSALIARLKKENID--FVYYGGYYPEMG----QMLRQARSVGLKTQFMGPE 249 + DF ++ R+K D F + P +G + ++ G+K G + Sbjct: 174 VRMPLATTDFGPIMQRIKDSGADMIFTFLPAGPPTLGFVKAYIDNGLKAAGVKLMSTG-D 232 Query: 250 GVGNASLSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALK 289 V L NI GD+ G+L T D P N+ + L+ Sbjct: 233 VVTEPDLPNI-GDSGIGILSTYHYAVSHDSPENKAFLALLQ 272 >4F06-A nrPDB Length = 371 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 51/209 (24%), Positives = 96/209 (45%), Gaps = 22/209 (10%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVG--VEY----DDAC 76 AD IKV V+G MSGP A +G G I+A G+K+ G VE+ + + Sbjct: 3 ADTIKVGVIGTMSGPYALFGKNYKMG-------IDAWVAEHGNKVAGHTVEFVYRDEVSP 55 Query: 77 DPKQAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQ 135 +P Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ Sbjct: 56 NPAQSKALAQELIVKEKVQYLAGLYFTPNAMAVAPLLQEAKVPMVVMNAATSSITEKS-P 114 Query: 136 HIMRTAGLDSSQGPTAAKYILETVKPQRIAI-IHDKQQYGEGL--ARSVQDGLKAANANV 192 +I+RT+ Q A + + ++AI + D YG G+ + + +A V Sbjct: 115 YIVRTS-FTMFQNTVPAAKVAKQKGATKVAIAVSD---YGPGIDAETAFKKTFEAEGGKV 170 Query: 193 VFFDGITAGEKDFSALIARLKKENIDFVY 221 V + DF ++ R+K D ++ Sbjct: 171 VEAVRMPLSTTDFGPIMQRIKNSGADMIF 199 >4F11-A nrPDB Length = 433 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 13/112 (11%) Query: 72 YDDACDPKQAVAVANKIVNDGIKY------VIGHLCSSSTQPASDIYEDEGILMISPGAT 125 YD CD + + K D IKY V G +C S T ++ + ++ +S AT Sbjct: 63 YDTECDNAKGL----KAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAAT 118 Query: 126 NPELT-QRGYQHIMRTAGLDSSQGPTAAKYILETVKPQRI-AIIHDKQQYGE 175 P L ++ Y + RT D++ P K +L+ + +R+ + D Q++ E Sbjct: 119 TPVLADKKKYPYFFRTVPSDNAVNPAILK-LLKHYQWKRVGTLTQDVQRFSE 169 >1QO0-A nrPDB Length = 385 Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust. Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 48 GARQAIKDINAKGGIKGDKLVGVEYDDACDP-KQAVAVANKIVNDGIKYVIGHLCSSSTQ 106 GA A++ +N +GG+ G + + D DP + + + I N G+++++G S + + Sbjct: 30 GALLAVEQLNREGGVGGRPIETLSQDPGGDPDRYRLCAEDFIRNRGVRFLVGCYMSHTRK 89 Query: 107 PASDIYEDEGILMISP 122 + E L+ P Sbjct: 90 AVMPVVERADALLCYP 105 >3H5L-A nrPDB Length = 419 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 157 ETVKPQ-RIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKE 215 E +P +IAII Y +A +++DG +V F+ + D+ +A+L+ + Sbjct: 159 EFSRPNNKIAIITGPGIYSVNIANAIRDGAGEYGYDVSLFETVAIPVSDWGPTLAKLRAD 218 Query: 216 NIDFVYYGGYYPE-----MGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGM 267 + +YP+ M Q + + + Q+ G A+ +IAGD + G+ Sbjct: 219 PPAVIVVTHFYPQDQALFMNQFMTDPTNSLVYLQY----GASLAAFRDIAGDNSVGV 271 >5X2M-A nrPDB Length = 461 Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 13/83 (15%) Query: 294 DPSGPYVWITYAAVQSLATALE---RTGSD--------EPLALVKDLKANGANTVIGPLN 342 DPS + + YAAV ++A AL R GSD P ++++LK + + + Sbjct: 343 DPS--FSFPVYAAVYAIAHALHNTLRCGSDRCPKNITVHPHMILEELKKSNFTLLNQTVQ 400 Query: 343 WDEKGDLKGFDFGVFQWHADGSS 365 +DE GD K V W++ G++ Sbjct: 401 FDENGDPKFGSLSVVFWNSSGNA 423 >3CPG-A nrPDB Length = 282 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 20/81 (24%) Query: 69 GVEYDDACDPKQAVAVANKI-VNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNP 127 G E CDP A+ +A KI DGI+ +G++ I + Sbjct: 171 GEESKSGCDPAHAIRIAQKIGTLDGIEL-------------------QGLMTIGAHVHDE 211 Query: 128 ELTQRGYQHIMRTAGLDSSQG 148 + +RG+ H+ +T L + G Sbjct: 212 TVIRRGFSHLRKTRDLILASG 232 >3WCZ-A nrPDB Length = 308 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 30/136 (22%), Positives = 58/136 (42%), Gaps = 23/136 (16%) Query: 165 AIIHDKQQYGEGLARSVQDGLKAANANVV---FFDGITAGEKDFSALIARLKKENIDFV- 220 A+ D++Q G+G+A ++ +GL V ++ A ++ AL LKK +D++ Sbjct: 56 AVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYID 115 Query: 221 YYGGYYP---------------EMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAE 265 Y ++P E Q ++ AR +GL GV N + + I + Sbjct: 116 LYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI----GVSNFNATQITRLVSN 171 Query: 266 GMLVTMPKRYDQDPAN 281 + + + + +P N Sbjct: 172 SYIRPVINQIEVNPTN 187 >2PCL-A nrPDB Length = 224 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 9/81 (11%) Query: 64 GDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV----IGHLCSSSTQPASDIYE--DEG- 116 GDKL Y+ + +Q VA+A + N+ I G+L S++T+ DI+ +EG Sbjct: 131 GDKLSRKPYELSGGEQQRVAIARALANEPILLFADEPTGNLDSANTKRVMDIFLKINEGG 190 Query: 117 --ILMISPGATNPELTQRGYQ 135 I+M++ ELT R + Sbjct: 191 TSIVMVTHERELAELTHRTLE 211 >3K4W-A nrPDB Length = 291 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 11/99 (11%) Query: 55 DINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV---------IGHLCSSST 105 D+ A DK V +A K+A+A +I++ GI+ V H+ Sbjct: 81 DVAAVAKAYPDKFHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGVWATPMHVDDRRL 140 Query: 106 QPASDIYEDEGI--LMISPGATNPELTQRGYQHIMRTAG 142 P ED GI +M++ G P++T +HI R G Sbjct: 141 YPLYAFCEDNGIPVIMMTGGNAGPDITYTNPEHIDRVLG 179 >2OV1-A nrPDB Length = 260 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 6/49 (12%) Query: 160 KPQRIAIIHDKQQY---GEGLARSVQDGLKAANANVVFFD---GITAGE 202 KPQ++A + + + Y G G + + LKAANAN+ D GIT E Sbjct: 42 KPQQLAALSEAEAYVLIGLGFEQPWLEKLKAANANMKLIDSAQGITPLE 90 >1PQ4-A nrPDB Length = 291 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 6/51 (11%) Query: 160 KPQRIAIIHDKQQY---GEGLARSVQDGLKAANANVVFFD---GITAGEKD 204 KPQ++A + + + Y G G + + LKAANAN+ D GIT E + Sbjct: 42 KPQQLAALSEAEAYVLIGLGFEQPWLEKLKAANANMKLIDSAQGITPLEME 92 >4ZTY-A nrPDB Length = 769 Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 24/47 (51%) Query: 288 LKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA 334 L ++KK PS Y W ++A + A EP A+ +L+AN A Sbjct: 340 LASEKKLPSDVYEWFSFAVEKVKEVATLAKAVTEPEAVKAELEANAA 386 >3ILS-A nrPDB Length = 265 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 14/84 (16%) Query: 227 PEMGQMLRQARSVGLKTQFMGPEGVGN----ASLSNIAGDAAEGMLVTMPKRYDQDPANQ 282 P +L+ V KT FM P+G G+ ASL + D A +V + Y +DP N Sbjct: 7 PSTSVVLQGLPMVARKTLFMLPDGGGSAFSYASLPRLKSDTA---VVGLNCPYARDPENM 63 Query: 283 GIVDALKAD-------KKDPSGPY 299 + ++ P GPY Sbjct: 64 NCTHGAMIESFCNEIRRRQPRGPY 87 >4M88-A nrPDB Length = 357 Score = 27.7 bits (60), Expect = 9.3, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDD 74 I + +G +GP+A G + + N GGI+G KL E DD Sbjct: 5 IVLGQIGPFTGPLAADAAGLNQGIKAYLAQANKAGGIRGQKLTLFEADD 53 >1RK6-A nrPDB Length = 496 Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 6/67 (8%) Query: 32 GAMSGPIAQWGDMEFNGARQAIKDINAKG-----GIKGDKLVGVEYDDACDPKQAVAVAN 86 G+MS P A D +G I NA G G++GD++ V A ++ + VA Sbjct: 11 GSMSQPDATPFDYILSGG-TVIDGTNAPGRLADVGVRGDRIAAVGDLSASSARRRIDVAG 69 Query: 87 KIVNDGI 93 K+V+ G Sbjct: 70 KVVSPGF 76 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1USI-A nrPDB 477 e-135 1Z15-A nrPDB 437 e-123 4QWV-A nrPDB 347 4e-96 3IP9-A nrPDB 346 1e-95 4N0Q-A nrPDB 338 2e-93 4MLC-A nrPDB 294 3e-80 3I45-A nrPDB 263 6e-71 4MPT-A nrPDB 251 3e-67 4EVS-A nrPDB 225 3e-59 4XFK-A nrPDB 221 3e-58 4F06-A nrPDB 218 3e-57 4GNR-A nrPDB 215 2e-56 4MS4-A nrPDB 165 3e-41 Sequences not found previously or not previously below threshold: 1QO0-A nrPDB 112 3e-25 3H5L-A nrPDB 104 7e-23 4F11-A nrPDB 81 6e-16 3LMK-A nrPDB 81 8e-16 6N4Y-A nrPDB 79 2e-15 6N4X-A nrPDB 79 2e-15 5X2M-A nrPDB 77 1e-14 6BT5-A nrPDB 77 1e-14 1ISS-A nrPDB 75 5e-14 5C5C-A nrPDB 74 7e-14 4M88-A nrPDB 64 8e-11 5X2N-B nrPDB 54 1e-07 1YK0-A nrPDB 44 1e-04 2YFH-A nrPDB 36 0.023 5L2E-A nrPDB 36 0.033 3NV9-A nrPDB 34 0.16 4FHN-X nrPDB 32 0.39 4ZTY-A nrPDB 31 1.00 3E8L-C nrPDB 31 1.2 3WWM-A nrPDB 30 1.6 4P98-A nrPDB 30 1.7 4KWT-A nrPDB 29 3.3 3MW8-A nrPDB 29 4.1 3DAF-A nrPDB 28 6.6 3CPT-A nrPDB 28 6.9 4AQ4-A nrPDB 28 8.0 3S99-A nrPDB 27 9.3 >1USI-A nrPDB Length = 346 Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats. Identities = 345/346 (99%), Positives = 345/346 (99%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA Sbjct: 1 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 60 Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL Sbjct: 61 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 120 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK Sbjct: 121 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 180 Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA Sbjct: 181 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 240 Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL Sbjct: 241 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 300 Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSST AK Sbjct: 301 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTKAK 346 >1Z15-A nrPDB Length = 344 Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats. Identities = 273/346 (78%), Positives = 305/346 (88%), Gaps = 2/346 (0%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83 +DIKVAVVGAMSGP+AQ+GD EF GA QA+ DINAKGGIKG+KL V+YDDACDPKQAVA Sbjct: 1 EDIKVAVVGAMSGPVAQYGDQEFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVA 60 Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 VANK+VNDGIKYVIGHLCSSSTQPASDIYEDEGILMI+P AT PELT RGYQ I+RT GL Sbjct: 61 VANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGL 120 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203 DS QGPTAAKYILE VKPQRIAI+HDKQQYGEGLAR+VQDGLK NANVVFFDGITAGEK Sbjct: 121 DSDQGPTAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEK 180 Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDA 263 DFS L+ARLKKENIDFVYYGGY+PEMGQ+LRQAR+ GLKTQFMGPEGV N SLSNIAG++ Sbjct: 181 DFSTLVARLKKENIDFVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGES 240 Query: 264 AEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPL 323 AEG+LVT PK YDQ PAN+ IVDA+KA K+DPSG +VW TYAA+QSL L + SD+P Sbjct: 241 AEGLLVTKPKNYDQVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQ--SDDPA 298 Query: 324 ALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369 + K LKAN +TV+GPL WDEKGDLKGF+FGVF WHA+G++T AK Sbjct: 299 EIAKYLKANSVDTVMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK 344 >4QWV-A nrPDB Length = 321 Score = 347 bits (891), Expect = 4e-96, Method: Composition-based stats. Identities = 231/330 (70%), Positives = 253/330 (76%), Gaps = 12/330 (3%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 83 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA Sbjct: 2 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVA 61 Query: 84 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL Sbjct: 62 VANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 121 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEK 203 DSSQGPTAAKYILETVKPQR+ I+ D + + ++ + Sbjct: 122 DSSQGPTAAKYILETVKPQRVLIVDD---------AAFMRMMLKDIITKAGYE-VAGEAT 171 Query: 204 DFSALIARLKKENIDFVYYGGYYPEMGQM--LRQARSVGLKTQFMGPEGVGNASLSNIAG 261 + + + K+ D V PEM + +++ + + + +G ++ A Sbjct: 172 NGREAVEKYKELKPDIVTMDITMPEMNGIDAIKEIMKIDPNAKIIVCSAMGQQAMVIEAI 231 Query: 262 DAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDE 321 A + PKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDE Sbjct: 232 KAGAKDFIVKPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDE 291 Query: 322 PLALVKDLKANGANTVIGPLNWDEKGDLKG 351 PLALVKDLKANGANTVIGPLNWDEKGDLKG Sbjct: 292 PLALVKDLKANGANTVIGPLNWDEKGDLKG 321 >3IP9-A nrPDB Length = 356 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 139/335 (41%), Positives = 205/335 (61%), Gaps = 1/335 (0%) Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84 D+ +AV ++GP A +G GA QA KDINA GGI G+++ V DD DPKQ ++V Sbjct: 2 DVVIAVGAPLTGPNAAFGAQIQKGAEQAAKDINAAGGINGEQIKIVLGDDVSDPKQGISV 61 Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144 ANK V DG+K+V+GH S + PAS++Y + GIL I+P ATNP T+RG + RT G D Sbjct: 62 ANKFVADGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTERGLWNTFRTCGRD 121 Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204 QG A KY+ + K ++AIIHDK YG+GLA + AA V ++G+ G+KD Sbjct: 122 DQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAAGVTEVMYEGVNVGDKD 181 Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264 FSALI+++K+ + +Y+GG + E G ++RQA GLK + + +G+ + L++IAGDA Sbjct: 182 FSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAKLVSGDGIVSNELASIAGDAV 241 Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLA 324 EG L T P N+ +V+ KA +P Y +YAA+Q++A A + GS EP Sbjct: 242 EGTLNTFGPDPTLRPENKELVEKFKAAGFNPE-AYTLYSYAAMQAIAGAAKAAGSVEPEK 300 Query: 325 LVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQW 359 + + LK T +G +++DEKGD K + +++W Sbjct: 301 VAEALKKGSFPTALGEISFDEKGDPKLPGYVMYEW 335 >4N0Q-A nrPDB Length = 354 Score = 338 bits (867), Expect = 2e-93, Method: Composition-based stats. Identities = 134/337 (39%), Positives = 199/337 (59%), Gaps = 3/337 (0%) Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84 DI + V+ ++GP+A +GD GA A++ IN GGIKG+K+V DDA +PKQ V+ Sbjct: 10 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSA 69 Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144 AN+IV DGIK+V+G + + P SD+ + G+LM++P AT P+LT RG +++ RT G D Sbjct: 70 ANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRD 129 Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204 Q A Y+L+ +K +++A+IHDK YG+GLA + + + V +D +T G+KD Sbjct: 130 GQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKD 189 Query: 205 FSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAA 264 FSAL+ +LK + VY+GGY+ E G + RQ G++ +G EG+ N I G A Sbjct: 190 FSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNA 249 Query: 265 EGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGS-DEPL 323 +G L T K ++PA + + ALKA K P+ + YAAV+ + +ER GS D+ Sbjct: 250 QGTLFTNAKDATKNPAAKDAIQALKA-KNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSA 308 Query: 324 ALVKDLKA-NGANTVIGPLNWDEKGDLKGFDFGVFQW 359 A+ K L T IG L + E GDL F +F+W Sbjct: 309 AVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKW 345 >4MLC-A nrPDB Length = 356 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 103/348 (29%), Positives = 163/348 (46%), Gaps = 13/348 (3%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAV 82 +++I + V + P A D+ G A+++IN +GG++G KL V+ DD + ++ + Sbjct: 8 SEEIFIGV----AWPFASLDDLFAEGLELAVQEINEQGGVQGRKLSLVKADDEAELEKGL 63 Query: 83 AVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTA 141 A+A N GI+ VIGH S + PA+ IY+ G++M+SP +T+P+LT GY H+ R Sbjct: 64 AIAQAFADNAGIQAVIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDHGYIHVFRNI 123 Query: 142 GLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAG 201 D A Y+ E +R+ I + YG GLA + +D +A +V Sbjct: 124 PSDQEIARQLAIYLAEQ-GHERMVIYYTDDSYGNGLANAFEDYARAQGITIVDRFNYYGN 182 Query: 202 EKDFSALIARLKKENIDFVYYGGYYPEMG-QMLRQARSVGLKTQFMGPEGVGNASLSNI- 259 KD L + + +D ++ G + L A+SVG++ + SL+ Sbjct: 183 LKDLERLYDKWQAFGMDGIFIAKTATGGGTEFLVDAKSVGIEVPLIAGNSWDALSLTEDI 242 Query: 260 --AGDAAEGMLVTMPKRYD-QDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALER 316 G AEG+LV D Q V+A + + P Y Y AV LA ALE+ Sbjct: 243 ENIGMTAEGLLVGSFFNPQRPDSRTQDFVEAFRREYGQPPTSYAAAGYDAVILLAEALEK 302 Query: 317 TGSDEPLALVKDLKANGA-NTVIGPLNWDEKGDLKGFDFGVFQWHADG 363 + P L + L+ G V+G +D +GD G D V + DG Sbjct: 303 SDLTHPATLAQGLRDLGPWEGVMGMHRFDGRGDDIG-DLVVLKKMKDG 349 >3I45-A nrPDB Length = 387 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 81/331 (24%), Positives = 145/331 (43%), Gaps = 16/331 (4%) Query: 24 DDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDK-LVGVEYDDACDPKQAV 82 + I++ + + S I + NG + A++ INA GG+ G + L + DD DP +AV Sbjct: 4 EAIRIGEINSYS-QIPAFTLPYRNGWQLAVEQINAAGGLLGGRPLEVISRDDGGDPGKAV 62 Query: 83 AVANKIVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELT-QRGYQHIMRT 140 A +++ G+ + G S SD +L ++ LT ++G ++ R Sbjct: 63 TAAQELLTRHGVHALAGTFLSHVGLAVSDFARQRKVLFMASEPLTDALTWEKGNRYTYRL 122 Query: 141 AGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVF-FDGIT 199 Q A + R A I +YG+ ++ L AA V F + Sbjct: 123 RPSTYMQAAMLAAEAA-KLPITRWATIAPNYEYGQSAVARFKELLLAARPEVTFVAEQWP 181 Query: 200 AGEK-DFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNAS--- 255 A K D + L++ + ++ + ++ + +R+ R GL F G + V + Sbjct: 182 ALYKLDAGPTVQALQQAEPEGLFNVLFGADLPKFVREGRVRGL---FAGRQVVSMLTGEP 238 Query: 256 --LSNIAGDAAEGMLVTMPKRYDQDPA-NQGIVDALKADKKDPSGPYVWITYAAVQSLAT 312 L+ + +A EG +VT YD D A ++ V+A +A K+ + Y + ++A Sbjct: 239 EYLNPLKDEAPEGWIVTGYPWYDIDTAPHRAFVEAYRARWKEDPFVGSLVGYNTLTAMAV 298 Query: 313 ALERTGSDEPLALVKDLKANGANTVIGPLNW 343 A E+ G E LV+ LK +T +GPL++ Sbjct: 299 AFEKAGGTESETLVETLKDMAFSTPMGPLSF 329 >4MPT-A nrPDB Length = 380 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 139/345 (40%), Gaps = 33/345 (9%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVG-VEYDDACDPKQA 81 AD IK+ + A++GP ++G+ A++ NAKGGI G K+ + DD +P +A Sbjct: 4 ADTIKIGMTSALTGPYNEFGEGNRRAVELAVEQWNAKGGINGKKIEIAMLLDDQLNPDRA 63 Query: 82 VAVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGY------ 134 V I+ N I +IG S D+ + +G ++P A P +T G Sbjct: 64 VQNIRAILDNKDIVGIIGPAGSGPMLAVIDMVQADGRPYMNPIAQTPVVTYPGEKTGEKP 123 Query: 135 -QHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGL-KAANANV 192 ++ A + + +Y+ + +R+ IIH+ YG + + K A Sbjct: 124 RPNVFSFALQNDIEAVAMGEYLAKKF--KRVGIIHESTAYGVTGVDYLAASIAKNGGAKP 181 Query: 193 VFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVG 252 V D G +D +A +AR+K+ N+D + G ++ + R + + G Sbjct: 182 VATDSYNQGAQDMTAQVARMKRANVDAIAAIGLGKDLAVLRRTMARLNVNVPLAASNGAL 241 Query: 253 NASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADK----------KDPSGPYVWI 302 AG+ G L TM + +P D KA K DP P +++ Sbjct: 242 GQPYQEGAGELTLGTLGTMIGAFG-NPMRAPAADFAKAYKAKYGTDRWWGNDPENPQLFM 300 Query: 303 ------TYAAVQSLATALERTGSDEPLALVKDLKA----NGANTV 337 Y A L + S +P A++ +++ G NT Sbjct: 301 AISVSNGYDAANILFEGIRLANSTDPKAVIAAIESIKDYQGVNTA 345 >4EVS-A nrPDB Length = 371 Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats. Identities = 76/336 (22%), Positives = 136/336 (40%), Gaps = 22/336 (6%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIK-GDKLVGVEYDDA--CDPK 79 AD IKV V+G MSGP A +G G I A+ G K G V Y D +P Sbjct: 3 ADTIKVGVIGTMSGPYALFGQNFKMG----IDAWVAEHGNKVGGHTVEFVYRDEVSPNPA 58 Query: 80 QAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIM 138 Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ +I+ Sbjct: 59 QSKALAQELIVKEKVQYIAGLYFTPNAMAVAPLLQEAKVPMVVLNAATSSITEKS-PYIV 117 Query: 139 RTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI 198 RT+ Q A + + +++AI G + + +A +VV + Sbjct: 118 RTS-FTMFQNTVPAAKVAKQKGAKKVAIAVSDYGPGIDAETAFKKTFEAEGGSVVEAVRM 176 Query: 199 TAGEKDFSALIARLKKENIDFV--YYGGYYPEMG----QMLRQARSVGLKTQFMGPEGVG 252 DF ++ R+K D + + P +G + ++ G+K G + V Sbjct: 177 PLATTDFGPIMQRIKDSGADMIFTFLPAGPPTLGFVKAYIDNGLKAAGVKLMSTG-DVVT 235 Query: 253 NASLSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALKADKKDPSGP--YVWITYAAVQS 309 L NI GD+ G+L T D P N+ + L+ Y + Sbjct: 236 EPDLPNI-GDSGIGILSTYHYAVSHDSPENKAFLALLQKGGAKLGDVTMTSVAAYDGARL 294 Query: 310 LATALERTGS-DEPLALVKDLKANGANTVIGPLNWD 344 + +E TG +P + +K + GP++ D Sbjct: 295 IYKMIEATGGKQDPEKAIAAVKDMKWTSPRGPVSID 330 >4XFK-A nrPDB Length = 399 Score = 221 bits (564), Expect = 3e-58, Method: Composition-based stats. Identities = 81/349 (23%), Positives = 146/349 (41%), Gaps = 28/349 (8%) Query: 15 LAISHTAMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDD 74 +A H A+ +K+A+V +SGP A G + + IN GG G+K+ +EYD+ Sbjct: 1 MAHHHHHHAEPLKIALVETLSGPQASTGLLYRAAVLYQLGKINEAGGFNGEKIQILEYDN 60 Query: 75 ACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYED----------EGILMISPGA 124 P A + DG + ++ SS+ A I ED + +L ++ GA Sbjct: 61 QGGPVGAADRVKAAIADGAQIIV---QGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGA 117 Query: 125 TNPELT-QRGYQHIMRTAGLDSSQGPTAAKYILET-VKPQRIAIIHDKQQYGEGLARSVQ 182 ELT + + + R + + + T A+ + + + +R I+ +G + +V Sbjct: 118 EALELTGSKCHFYHFRFSPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTVV 177 Query: 183 DGLKAANANVVFFDGITAGE-KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGL 241 K VV + +DFS +A+++ N+D V+ G + ++ +++ A GL Sbjct: 178 ANAKEIGYEVVDKTLHEVNKIQDFSPYVAKIQAANVDTVFTGNWSNDLLLLMKAASGAGL 237 Query: 242 KTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPY-V 300 K +F + AG AEG +V+ P + AN A D K +G Y Sbjct: 238 KAKFAT-SFLDQPGNIGNAGAIAEGHIVSTPFNPE---ANGEASMAFAEDYKKVTGHYPS 293 Query: 301 WITYAAVQSLATALERTGSDEPLA-------LVKDLKANGANTVIGPLN 342 ++ AAV L E + +P + ++ T +G + Sbjct: 294 YVEPAAVFGLQLFGEALKNVKPGEGKINTTDIALAIENASVKTPMGDYS 342 >4F06-A nrPDB Length = 371 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 76/336 (22%), Positives = 137/336 (40%), Gaps = 22/336 (6%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIK--GDKLVGVEYDD-ACDPK 79 AD IKV V+G MSGP A +G G I A+ G K G + V D+ + +P Sbjct: 3 ADTIKVGVIGTMSGPYALFGKNYKMG----IDAWVAEHGNKVAGHTVEFVYRDEVSPNPA 58 Query: 80 QAVAVANK-IVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIM 138 Q+ A+A + IV + ++Y+ G + + + + ++ + M+ A +T++ +I+ Sbjct: 59 QSKALAQELIVKEKVQYLAGLYFTPNAMAVAPLLQEAKVPMVVMNAATSSITEKS-PYIV 117 Query: 139 RTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI 198 RT+ Q A + + ++AI G + + +A VV + Sbjct: 118 RTS-FTMFQNTVPAAKVAKQKGATKVAIAVSDYGPGIDAETAFKKTFEAEGGKVVEAVRM 176 Query: 199 TAGEKDFSALIARLKKENIDFV--YYGGYYPEMG----QMLRQARSVGLKTQFMGPEGVG 252 DF ++ R+K D + + P +G + ++ G+K G + V Sbjct: 177 PLSTTDFGPIMQRIKNSGADMIFTFLPAGPPTLGFVKAYIDNGLKAGGVKLMSTG-DVVT 235 Query: 253 NASLSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALKA--DKKDPSGPYVWITYAAVQS 309 L NI G+A G+L T D P N+ + L+ K D Y + Sbjct: 236 EPDLPNI-GEAGLGILSTYHYAVSHDSPENKAFLALLQKGGAKLDEVTMTSVAAYDGARL 294 Query: 310 LATALERT-GSDEPLALVKDLKANGANTVIGPLNWD 344 + +E T G +P + +K + G ++ D Sbjct: 295 IYKMIEATSGKSDPDKAIAAVKGMKWVSPRGEVSID 330 >4GNR-A nrPDB Length = 353 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 81/326 (24%), Positives = 147/326 (45%), Gaps = 12/326 (3%) Query: 25 DIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAV 84 IK+ SG +A +G E GA+ A+ +INA GGI G ++ V+ D+ + +A +V Sbjct: 7 TIKIGFNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASV 66 Query: 85 ANKIVND-GIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 +V + V+G S +T A G+ +ISP AT LT +G ++ Sbjct: 67 TTNLVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLT-KGQDYLFIGTFQ 125 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDK-QQYGEGLARSVQDGLKAANANVVFFDGITAGE 202 DS QG + Y+ E + +++ + D Y +G+A+S ++ K +V + AG+ Sbjct: 126 DSFQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYK---GEIVADETFVAGD 182 Query: 203 KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGD 262 DF A + ++K ++ D + GYY E G+++ QAR +G+ +G +G A Sbjct: 183 TDFQAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATA 242 Query: 263 AAEGMLVT---MPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGS 319 + + + +DA +A + + + Y +V +A A + G+ Sbjct: 243 EKASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAK--GA 300 Query: 320 DEPLALVKDL-KANGANTVIGPLNWD 344 + +L K V G ++D Sbjct: 301 KNSGEIKDNLAKTKDFEGVTGQTSFD 326 >4MS4-A nrPDB Length = 420 Score = 165 bits (417), Expect = 3e-41, Method: Composition-based stats. Identities = 72/369 (19%), Positives = 140/369 (37%), Gaps = 54/369 (14%) Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGD-KLVGVEYDDACDPKQAVAV 84 + + + MSG G A++D+N++ I D +L + +D CDP QA Sbjct: 6 VYIGALFPMSGGWPG-GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKY 64 Query: 85 ANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAG 142 +++ ND IK ++ CSS + ++ ++++S G+++P L+ R + RT Sbjct: 65 LYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHP 124 Query: 143 LDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGE 202 + PT K + E ++IA I + +++ +K A + F Sbjct: 125 SATLHNPTRVK-LFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSF---F 180 Query: 203 KDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQ-----FMG--PEGVGNAS 255 D + + LK+++ + Y E ++ + L + +G + Sbjct: 181 SDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIY 240 Query: 256 LSNIA------GDAAEGMLVTMPKRYDQDPAN---------QGIVDAL-KADKKDPSGPY 299 +I +A EG + T +PAN Q V+ L K K+ P Sbjct: 241 DPSINCTVDEMTEAVEGHITTEI--VMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETG 298 Query: 300 VW----ITYAAVQSLATALERT-----------------GSDEPLALVKDLKANGANTVI 338 + + Y A+ +LA AL +T + + + ++ V Sbjct: 299 GFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS 358 Query: 339 GPLNWDEKG 347 G + +D G Sbjct: 359 GHVVFDASG 367 >1QO0-A nrPDB Length = 385 Score = 112 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 56/351 (15%), Positives = 121/351 (34%), Gaps = 12/351 (3%) Query: 21 AMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQ 80 + + + ++ + +G A + GA A++ +N +GG+ G + + D DP + Sbjct: 3 SHQERPLIGLLFSETGVTADIERSQRYGALLAVEQLNREGGVGGRPIETLSQDPGGDPDR 62 Query: 81 AVAVANKIV-NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMR 139 A + N G+++++G S + + + E L+ P P +I+ Sbjct: 63 YRLCAEDFIRNRGVRFLVGCYMSHTRKAVMPVVERADALLCYP---TPYEGFEYSPNIVY 119 Query: 140 TAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGIT 199 + A Y++ +R+ I Y ++ + V+ I Sbjct: 120 GGPAPNQNSAPLAAYLIRHYG-ERVVFIGSDYIYPRESNHVMRHLYRQHGGTVLEEIYIP 178 Query: 200 A--GEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSV--GLKTQFMGPEGVGNAS 255 + D + R+ + D V+ ++ R + + A Sbjct: 179 LYPSDDDLQRAVERIYQARADVVFSTVVGTGTAELYRAIARRYGDGRRPPIASLTTSEAE 238 Query: 256 LSNIAGDAAEGMLVTMPKRYDQD-PANQGIVDALKADKKDPSGPYVW--ITYAAVQSLAT 312 ++ + D AEG +V P D PA++ V A + + W Y L Sbjct: 239 VAKMESDVAEGQVVVAPYFSSIDTPASRAFVQACHGFFPENATITAWAEAAYWQTLLLGR 298 Query: 313 ALERTGSDEPLALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADG 363 A + G+ + + L + GP+ + + + + + A G Sbjct: 299 AAQAAGNWRVEDVQRHLYDIDIDAPQGPVRVERQNNHSRLSSRIAEIDARG 349 >3H5L-A nrPDB Length = 419 Score = 104 bits (259), Expect = 7e-23, Method: Composition-based stats. Identities = 63/344 (18%), Positives = 127/344 (36%), Gaps = 23/344 (6%) Query: 23 ADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAV 82 +D + + ++G +A G G + A +INA GGI G + V D V Sbjct: 12 SDPVVIGCPAPLTGIVAADGIEFQRGIQMAADEINAVGGILGRPIELVFADTQSKGVDVV 71 Query: 83 -AVANKIVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMI--SPGATNPELTQRG---YQ 135 A ++++ D +I + D+ D G++ + + A + E+ + Y Sbjct: 72 IQSAQRLIDRDNASALIAGYNLENGTALHDVAADAGVIAMHANTVAVHDEMVKSDPDRYW 131 Query: 136 HIMRTAGLDSSQGPTAAKYILE-------TVKPQRIAIIHDKQQYGEGLARSVQDGLKAA 188 + ++ G K++ + + +IAII Y +A +++DG Sbjct: 132 GTFQYDPPETLYGGGFLKFLKDIEDNGEFSRPNNKIAIITGPGIYSVNIANAIRDGAGEY 191 Query: 189 NANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYP-EMGQMLRQARSVGLKTQFMG 247 +V F+ + D+ +A+L+ + + +YP + + Q + + Sbjct: 192 GYDVSLFETVAIPVSDWGPTLAKLRADPPAVIVVTHFYPQDQALFMNQFMTDPTNSLVYL 251 Query: 248 PEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKD-PSGPYVWITYAA 306 G A+ +IAGD + G+ QD A K D S TY+A Sbjct: 252 QYGASLAAFRDIAGDNSVGVTYATVLGTLQDEMGDAFAKAYKERYGDLSSTASGCQTYSA 311 Query: 307 VQSLATALERT-------GSDEPLALVKDLKANGANTVIGPLNW 343 + + + A + A+ L++ +G + + Sbjct: 312 LYAYSIAAALAGGPGAPYDDVQNKAVADRLRSLIFRGPVGTMRF 355 >4F11-A nrPDB Length = 433 Score = 81.4 bits (199), Expect = 6e-16, Method: Composition-based stats. Identities = 33/184 (17%), Positives = 69/184 (37%), Gaps = 7/184 (3%) Query: 40 QWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKY--VI 97 G AI+ I + ++ L YD CD + + + G + V Sbjct: 31 SIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVF 90 Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQ-RGYQHIMRTAGLDSSQGPTAAKYIL 156 G +C S T ++ + ++ +S AT P L + Y + RT D++ P K +L Sbjct: 91 GGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILK-LL 149 Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKEN 216 + + +R+ + Q + + L + + + + D + +LK + Sbjct: 150 KHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFS---NDPCTSVKKLKGND 206 Query: 217 IDFV 220 + + Sbjct: 207 VRII 210 >3LMK-A nrPDB Length = 492 Score = 81.0 bits (198), Expect = 8e-16, Method: Composition-based stats. Identities = 54/307 (17%), Positives = 107/307 (34%), Gaps = 46/307 (14%) Query: 8 IIAGMIALAISHTAMADDI---KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKG 64 II G + ++ H D + K V Q+G ++ IN+ + Sbjct: 22 IIIGAL-FSVHHQPTVDKVHERKCGAVRE------QYGIQRVEAMLHTLERINSDPTLLP 74 Query: 65 DKLVGVEYDDAC-----DPKQAVAVANKIV----------------------NDGIKYVI 97 + +G E D+C +Q++ + I VI Sbjct: 75 NITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVI 134 Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYIL 156 G SS ++ + I I+ AT+ +L+ + +++ MR D+ Q I+ Sbjct: 135 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVD-IV 193 Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFSALIARLKK 214 + ++ +H + YGE + +D ++ I AGE+ F L+ +L Sbjct: 194 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGISIAHSYKIYSNAGEQSFDKLLKKLTS 253 Query: 215 ENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNA-SLSNIAGDAAEGMLV 269 + M +L R +GL + +G +G + +++ A G + Sbjct: 254 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 313 Query: 270 TMPKRYD 276 + D Sbjct: 314 IKLQSPD 320 >6N4Y-A nrPDB Length = 596 Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 54/307 (17%), Positives = 106/307 (34%), Gaps = 46/307 (14%) Query: 8 IIAGMIALAISHTAMADDI---KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKG 64 II G + ++ H D + K V Q+G ++ IN+ + Sbjct: 52 IIIGAL-FSVHHQPTVDKVHERKCGAVRE------QYGIQRVEAMLHTLERINSDPTLLP 104 Query: 65 DKLVGVEYDDAC-----DPKQAVAVANKIV----------------------NDGIKYVI 97 + +G E D+C +Q++ + I VI Sbjct: 105 NITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVI 164 Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYIL 156 G SS ++ + I I+ AT+ +L+ + +++ MR D+ Q I+ Sbjct: 165 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVD-IV 223 Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFSALIARLKK 214 + ++ +H + YGE + +D + I AGE+ F L+ +L Sbjct: 224 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTS 283 Query: 215 ENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNA-SLSNIAGDAAEGMLV 269 + M +L R +GL + +G +G + +++ A G + Sbjct: 284 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 343 Query: 270 TMPKRYD 276 + D Sbjct: 344 IKLQSPD 350 >6N4X-A nrPDB Length = 877 Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 54/307 (17%), Positives = 106/307 (34%), Gaps = 46/307 (14%) Query: 8 IIAGMIALAISHTAMADDI---KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKG 64 II G + ++ H D + K V Q+G ++ IN+ + Sbjct: 41 IIIGAL-FSVHHQPTVDKVHERKCGAVRE------QYGIQRVEAMLHTLERINSDPTLLP 93 Query: 65 DKLVGVEYDDAC-----DPKQAVAVANKIV----------------------NDGIKYVI 97 + +G E D+C +Q++ + I VI Sbjct: 94 NITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVI 153 Query: 98 GHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQGPTAAKYIL 156 G SS ++ + I I+ AT+ +L+ + +++ MR D+ Q I+ Sbjct: 154 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVD-IV 212 Query: 157 ETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFSALIARLKK 214 + ++ +H + YGE + +D + I AGE+ F L+ +L Sbjct: 213 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTS 272 Query: 215 ENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNA-SLSNIAGDAAEGMLV 269 + M +L R +GL + +G +G + +++ A G + Sbjct: 273 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 332 Query: 270 TMPKRYD 276 + D Sbjct: 333 IKLQSPD 339 >5X2M-A nrPDB Length = 461 Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 62/377 (16%), Positives = 137/377 (36%), Gaps = 62/377 (16%) Query: 46 FNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKI--VNDGIK--------- 94 F R ++++IN + + +G + D C + K+ VND I+ Sbjct: 52 FQMMRFSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWEDASTGL 111 Query: 95 ----YVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRT-AGLDSSQG 148 V+G S+ + I+ M+S G + ++ Y +RT Sbjct: 112 PNAIGVVGPFTSTHALSIAPIFMTNLFPMVSYGCSGSVFSKENLYPSFLRTVHSNKDVIN 171 Query: 149 PTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSAL 208 + + +A ++ +G+ ++ ++ + + F+ I D+ + Sbjct: 172 AIVGIIL--NFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSEICLAFYKAINVN-TDYLQV 228 Query: 209 IARLKKENIDFV--YYGGYYPEMGQMLRQARSVGLKTQF-MGPEGVG-NASLSNIAGDAA 264 +++++NI + + Y E ++ A + + + + +G N L ++ G Sbjct: 229 FKQIEEQNIKVIVVFAPKVYAEA--VVESAVQLNVTNKVWIADDGWSLNKKLPSMNGIQN 286 Query: 265 EGMLVTMPKRYDQDPANQGIVDAL--KADKKDPSG-----------------------PY 299 G ++ + + P + + + D D + Sbjct: 287 IGTVLGVAQPVVTIPGFTDFIYSAISQTDGGDTEQKMFCNQKCNCSNLSVKSLLNADPSF 346 Query: 300 VWITYAAVQSLATALE---RTGSD--------EPLALVKDLKANGANTVIGPLNWDEKGD 348 + YAAV ++A AL R GSD P ++++LK + + + +DE GD Sbjct: 347 SFPVYAAVYAIAHALHNTLRCGSDRCPKNITVHPHMILEELKKSNFTLLNQTVQFDENGD 406 Query: 349 LKGFDFGVFQWHADGSS 365 K V W++ G++ Sbjct: 407 PKFGSLSVVFWNSSGNA 423 >6BT5-A nrPDB Length = 479 Score = 76.8 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 76/417 (18%), Positives = 132/417 (31%), Gaps = 91/417 (21%) Query: 42 GDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACD-----PKQAVAVANKIVN------ 90 G AI IN + + +GV D C +Q++ ++ Sbjct: 36 GIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDV 95 Query: 91 -------------DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQH 136 D I VIG SS + ++I I IS +T PEL+ Y Sbjct: 96 KCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDF 155 Query: 137 IMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKA-ANANVVFF 195 R DS Q I+ + ++ + + YGE + + ++ Sbjct: 156 FSRVVPPDSYQAQAMVD-IVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVSIAQS 214 Query: 196 DGITAGEK--DFSALIAR-LKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQF--MGPEG 250 I + +F +I R L+ N V ++ ++L A+ + F +G + Sbjct: 215 QKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDS 274 Query: 251 VGNASLSN-IAGDAAEGMLVTMPKRYDQDPANQGI------------------------- 284 G+ + AEG + +PKR D ++ Sbjct: 275 WGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCK 334 Query: 285 ----------------VDALKADKKDPSGPYVWITYAAVQSLATALE------------- 315 ++ + D V AV S+A AL Sbjct: 335 LGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGL 394 Query: 316 --RTGSDEPLALVKDLKANGANTVIG-PLNWDEKGDLKGFDFGVFQWHADGSSTAAK 369 R + + L+ ++A N G P+ ++E GD G + +FQ+ ST K Sbjct: 395 CPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYK 450 >1ISS-A nrPDB Length = 490 Score = 74.8 bits (182), Expect = 5e-14, Method: Composition-based stats. Identities = 35/173 (20%), Positives = 69/173 (39%), Gaps = 8/173 (4%) Query: 90 NDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRG-YQHIMRTAGLDSSQG 148 I VIG SS ++ + I I+ AT+ +L+ + Y++ +R D+ Q Sbjct: 121 KKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQA 180 Query: 149 PTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGI--TAGEKDFS 206 I++ ++ +H + YGE + ++ + D I AGEK F Sbjct: 181 RAMLD-IVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFD 239 Query: 207 ALIARLKKENIDFVYYGGYYPEMGQ--MLRQARSVGL--KTQFMGPEGVGNAS 255 L+ +L++ + M +L R +G+ + +G +G + Sbjct: 240 RLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRD 292 >5C5C-A nrPDB Length = 481 Score = 74.5 bits (181), Expect = 7e-14, Method: Composition-based stats. Identities = 54/269 (20%), Positives = 94/269 (34%), Gaps = 35/269 (13%) Query: 42 GDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACD-----PKQAVAVANKIVN------ 90 G A+ IN+ + + +G D C +Q++ ++ Sbjct: 43 GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDV 102 Query: 91 -------------DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELT-QRGYQH 136 + + VIG SS + ++I I IS +T PEL+ R Y Sbjct: 103 RCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDF 162 Query: 137 IMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYG-EGLARSVQDGLKAANANVVFF 195 R DS Q I++ + ++ + + YG +G+ Q +A ++ Sbjct: 163 FSRVVPPDSFQAQAMVD-IVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLSIAQS 221 Query: 196 DGITAGEK----DFSALIARLKKE-NIDFVYYGGYYPEMGQMLRQARSVGLKTQF--MGP 248 I K DF +I +L N V ++ Q+L A+ F +G Sbjct: 222 VRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGS 281 Query: 249 EGVGNASLS-NIAGDAAEGMLVTMPKRYD 276 + G+ + D AEG + PKR Sbjct: 282 DSWGSKINPLHQHEDIAEGAITIQPKRAT 310 >4M88-A nrPDB Length = 357 Score = 64.1 bits (154), Expect = 8e-11, Method: Composition-based stats. Identities = 49/320 (15%), Positives = 105/320 (32%), Gaps = 13/320 (4%) Query: 26 IKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVA 85 I + +G +GP+A G + + N GGI+G KL E DD + Sbjct: 5 IVLGQIGPFTGPLAADAAGLNQGIKAYLAQANKAGGIRGQKLTLFEADDRFSGEGFAEQF 64 Query: 86 NKIVNDGIKYVIGHLCSSSTQPASD--IYEDEGILMISPGATNPELTQRGYQHIMRTAGL 143 K + +I + S++ + D + + +++++ L G+ Sbjct: 65 PKAMEKKPLALISPMGSAAIKRMLDDKLLDTAPVVVVNGVPGAESLRTPGHPKFFHVRAG 124 Query: 144 DSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAG-- 201 D + + + + ++A ++ G VQ+ +K + +G+ +G Sbjct: 125 DKQEIEEIVSH-AQMLGMSKLATLYQDLPTGTSGMAVVQEAVKTVPGGKIELNGVKSGPD 183 Query: 202 EKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAG 261 +A ++ V G P + + R + V A + + G Sbjct: 184 AAALAAAARQIAALGAQGVLVIGPPPFIVAGIAALRKADVTQPLFVLSYVSAAQIVKVVG 243 Query: 262 DAAEGMLVTMPKRYDQD----PANQGIVDALKADKKDPS--GPYVWITYAAVQSLATALE 315 A + + D + P + A+K + Y + +++ AL+ Sbjct: 244 VAGARGVGIVQAFPDPNDKMLPVQREFQAAMKEAFPQMQEYTEFQLEGYLSARTVGEALK 303 Query: 316 --RTGSDEPLALVKDLKANG 333 + L L G Sbjct: 304 HPKNTGLSAANLAATLSTMG 323 >5X2N-B nrPDB Length = 478 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 58/379 (15%), Positives = 111/379 (29%), Gaps = 76/379 (20%) Query: 42 GDMEFNGARQAIKDINAKGGIKGD-KLVGVEYDDACDPKQAVAVANKIVNDG-------- 92 G + A+++INA + KL Y+ V A + + Sbjct: 53 GLGRALVMKYAVEEINANSQLLPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVE 112 Query: 93 ---------IKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQR-GYQHIMRTAG 142 + VIG S + + IS GAT+ + + Y RT Sbjct: 113 CNYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLVYPSFFRTVP 172 Query: 143 LDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGE 202 D Q + +++ +A++ +++YG+ + + V + G+ Sbjct: 173 SDIRQVDAMVQ-LIKKFNWNWVAVVGSEEEYGQQGVQQFSKKAEDMGV-CVAYQGLIPIY 230 Query: 203 KDFSALIA----RLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNA---- 254 D I ++ + V + L ++ + Sbjct: 231 DDPKPAIQTIINNIQTTEVKVVVVFSLVSPAVSFFEEVIKKNLTGVWIASSSWAISDKVY 290 Query: 255 SLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDAL------KADKKDPSGPY--------- 299 SL NI + G ++ + + L + + P PY Sbjct: 291 SLPNID---SIGTVIGFIDETETLELLSPFTEVLFKKIHEASPTEKPEDPYNPCPECWSL 347 Query: 300 ----------------VWITYAAVQSLATALER-----------TGSDE--PLALVKDLK 330 + YAAV ++A AL + + S P L++ LK Sbjct: 348 SPANVSLVKEESVQRTAFSVYAAVYTVAHALHKLLECNSAACKWSSSTRLYPWKLLEVLK 407 Query: 331 ANGANTVIGPLNWDEKGDL 349 N L +D+ G+ Sbjct: 408 EFSVNISNTSLKFDQNGNP 426 >1YK0-A nrPDB Length = 480 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 21/161 (13%), Positives = 53/161 (32%), Gaps = 9/161 (5%) Query: 64 GDKLVGVEYDDACDPKQAVAVANKIVND-GIK--YVIGHLCSSSTQPASDIYEDEGILMI 120 G + D C + ++ +++ G K ++G +C + P + + + M+ Sbjct: 96 GTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPML 155 Query: 121 SPGATNPELTQR--GYQHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEG-- 176 S GA + Y H+ R A + G + R A+++ + Sbjct: 156 SAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLA-LFRHHHWSRAALVYSDDKLERNCY 214 Query: 177 -LARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKEN 216 V + + + + + D ++ ++ Sbjct: 215 FTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASE 255 >2YFH-A nrPDB Length = 448 Score = 36.3 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 9/118 (7%) Query: 82 VAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTA 141 V A++++ +G+K V +T A+++++ G+L A N + T+ Sbjct: 328 VDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAG--------GVATS 379 Query: 142 GLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLK-AANANVVFFDGI 198 GL+ +Q + E V + I+ D A G A AN+V F I Sbjct: 380 GLEMAQNAARLGWKAEKVDARLHHIMTDIHDGSAAAAERYGLGYNLVAGANIVGFQKI 437 >5L2E-A nrPDB Length = 688 Score = 35.6 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 52/351 (14%), Positives = 107/351 (30%), Gaps = 55/351 (15%) Query: 49 ARQAIKDINAKGGI-KGDKLVG-VEYDDACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQ 106 R A+ D+N I + +K+ V + D +P QAV A +++N GI ++ + +S Sbjct: 23 FRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAG 82 Query: 107 PASDIYEDEGILMI---SPGATNP----ELT--QRGYQHIMRTAGLDSSQGPTAAKYILE 157 + + I + A P LT R + + ++ Sbjct: 83 SLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLNEVIL--RVVT 140 Query: 158 TVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENI 217 Q+ I +D +Y + D + +V K + L ++ E + Sbjct: 141 EYAWQKFIIFYDS-EYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEEL 199 Query: 218 ----DFV---YYGGYYPEMGQMLRQARSVGLKTQ----FMGPEGVGNASLSNIAGDA-AE 265 D + + + L + E + + + + + Sbjct: 200 NRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGR 259 Query: 266 GMLVTMPKRYDQDPANQGIVDALKADKK--DPSGPYV-------WITYAAVQSLATALER 316 ++ Q+ + + + DP P+ Y V LA A + Sbjct: 260 LTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEISNLYIYDTVLLLANAFHK 319 Query: 317 TGSDEP--------------------LALVKDLKANGANTVIGPLNWDEKG 347 D ++++ +K G N + G L + E G Sbjct: 320 KLQDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVNGLTGDLEFGENG 370 >3NV9-A nrPDB Length = 487 Score = 33.6 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 26/54 (48%) Query: 43 DMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV 96 D A +A+ + K GI D ++G + PK+A VA + + DG+ V Sbjct: 380 DNMAIAASRALAEFAEKRGINPDNIIGTMDEPGIFPKEAADVAMQAIKDGVARV 433 >4FHN-X nrPDB Length = 450 Score = 32.1 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Query: 82 VAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTA 141 V A++++ +G+K V +T A+++++ G+L A N + T+ Sbjct: 332 VDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAG--------GVATS 383 Query: 142 GLDSSQGPTAAKYILETVKPQ 162 GL+ +Q + E V + Sbjct: 384 GLEMAQNAARLGWKAEKVDAR 404 >4ZTY-A nrPDB Length = 769 Score = 30.9 bits (68), Expect = 1.00, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 24/47 (51%) Query: 288 LKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA 334 L ++KK PS Y W ++A + A EP A+ +L+AN A Sbjct: 340 LASEKKLPSDVYEWFSFAVEKVKEVATLAKAVTEPEAVKAELEANAA 386 >3E8L-C nrPDB Length = 185 Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 26/77 (33%) Query: 246 MGPEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYA 305 MG + + + GDA + L Y A G L +KD YV+ Sbjct: 1 MGHHHHHHMPVVDSDGDAVQLNLGGNYPLYTIQSAAIGFRGGLSTLRKDACKSYVYEAPE 60 Query: 306 AVQSLATALERTGSDEP 322 + L + + +P Sbjct: 61 TDRGLPVGFSASATSQP 77 >3WWM-A nrPDB Length = 269 Score = 30.2 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 46/145 (31%), Gaps = 10/145 (6%) Query: 85 ANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLD 144 A + +G+K ++ H S+ T ++ + PG LT R I Sbjct: 21 AASLWKEGVKLLLVHGGSAETNKVAEALGHPPRFLTHPGGQVSRLTDRKTLEIFEMVYCG 80 Query: 145 SSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKD 204 +L+ I + + G ++ ++ V D Sbjct: 81 LVNKRLV--ELLQKEGANAIGLSGLDGRLFVGRRKTAVKYVENGKVKV--------HRGD 130 Query: 205 FSALIARLKKENIDFVYYGGYYPEM 229 ++ + + K +D + GY P + Sbjct: 131 YTGTVEEVNKALLDLLLQAGYLPVL 155 >4P98-A nrPDB Length = 317 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 32/202 (15%), Positives = 66/202 (32%), Gaps = 7/202 (3%) Query: 76 CDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQ 135 DP QA V + G V+GH ++P + + + A+ Sbjct: 59 ADPTQAEPVIRQFAARGFDLVVGHGID-VSEPILRVATE--FPDVHFSASGDATLAERLP 115 Query: 136 HIMRTAGLDSSQGPTAAKYILETV-KPQRIAII-HDKQQYGEGLARSVQDGLKAANANVV 193 + D Q ++ ++ +++ + + + + ++ GLKAAN Sbjct: 116 PNVDGWTYDFGQLGYLDGFVAGSLRGVEKVGAVGGPQLPFVLATHKGIRAGLKAANPRAS 175 Query: 194 FFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGN 253 + + T D + +D + G+ L QA G +G Sbjct: 176 YEETYTGRFYDLQKEQEAARGL-LDKGAQLLVATDDGRGLGQAAVAG-DVPTIGVSAAAG 233 Query: 254 ASLSNIAGDAAEGMLVTMPKRY 275 A + + A+ L+ + Y Sbjct: 234 ADIKAVNITTAKLDLLPTYQSY 255 >4KWT-A nrPDB Length = 358 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 44/140 (31%), Gaps = 26/140 (18%) Query: 27 KVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVAN 86 K+ + + GP A W D E A QAI G K+ Sbjct: 204 KMGMDIRLVGPQAYWPDEELVAACQAIAK------QTGGKITL----------------T 241 Query: 87 KIVNDGIKYVIGHLCSS-STQPASDIYEDEGILMISPGATN-PELTQRGYQHIMRTAGLD 144 + V +G++ + S DE + ++ P N L Q G ++ L Sbjct: 242 ENVAEGVQGCDFLYTDVWVSMGESPEAWDERVALMKPYQVNMNVLKQTGNPNVKFMHCLP 301 Query: 145 SSQG--PTAAKYILETVKPQ 162 + T K + + + Sbjct: 302 AFHNDETTIGKQVADKFGMK 321 >3MW8-A nrPDB Length = 240 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 53/149 (35%), Gaps = 12/149 (8%) Query: 80 QAVAVANKIVND--GIKYVIGHLCSSSTQPASDIYEDE--GILMISPGATNPELTQRGYQ 135 +A AV +++ +I S+ + + + AT L +G Sbjct: 36 EAAAVTQAQLDELSRADILIFISTSAVSFATPWLKDQWPKATYYAVGDATADALALQG-I 94 Query: 136 HIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFF 195 R+ + LE V ++I I+ G+G ++ DGL+ ANV + Sbjct: 95 TAERSPADSQATEGLLTLPSLEQVSGKQIVIVR-----GKGGREAMADGLRLRGANVSYL 149 Query: 196 DGITAGEK--DFSALIARLKKENIDFVYY 222 + D A ++R + ID + Sbjct: 150 EVYQRACPPLDAPASVSRWQSFGIDTIVV 178 >3DAF-A nrPDB Length = 358 Score = 28.2 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 28/86 (32%), Gaps = 3/86 (3%) Query: 138 MRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDG 197 RT A + + V IA+ H YG L V D + ++ F + Sbjct: 11 YRTHAAAGITNFMRACEVAKEVGKPEIALTHSSITYGAELLHLVPDVKEVIVSDPCFAEE 70 Query: 198 ---ITAGEKDFSALIARLKKENIDFV 220 + E D ++ N + + Sbjct: 71 PGLVVIDEFDPKEVMEAHLSGNPESI 96 >3CPT-A nrPDB Length = 143 Score = 27.9 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 22/71 (30%) Query: 173 YGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQM 232 Y +G A ++ L +V I ++D +I + G+ Sbjct: 16 YFQGSADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALA 75 Query: 233 LRQARSVGLKT 243 Q +GL Sbjct: 76 TDQGSKLGLSK 86 >4AQ4-A nrPDB Length = 419 Score = 27.9 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 28/175 (16%), Positives = 58/175 (33%), Gaps = 17/175 (9%) Query: 56 INAKGGIKGDKL-VGVEYDDACDPKQAVAVANKI-VNDGIKYVIGHLCSSSTQPASDIYE 113 ++ G G ++ + +A +P + K + I + + +YE Sbjct: 11 WHSMEGELGKEVDSLAQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYE 70 Query: 114 DEGILMISPGATNPELTQRGYQHIMRTAG--LDSSQG-PTAAKYILETVKPQRIAIIHDK 170 M++ A P + + AG D SQ PT + Y ++ ++ Sbjct: 71 VGTATMMASKAIKPV------YDVFKEAGIQFDESQFVPTVSGYYSDSKTGH---LLSQP 121 Query: 171 QQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGY 225 + +D K A + + +D + A+LK + Y G+ Sbjct: 122 FNSSTPVLYYNKDAFKKAGLDP---EQPPKTWQDLADYAAKLKASGMKCGYASGW 173 >3S99-A nrPDB Length = 356 Score = 27.5 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 21/52 (40%), Gaps = 3/52 (5%) Query: 66 KLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGI 117 ++ + + DP + A +++ G+ + H S A + D GI Sbjct: 182 RVKVIWVNSWFDPGKEADAAKALIDQGVDIITQHTDS---TAAIQVAHDRGI 230 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.122 0.281 Lambda K H 0.267 0.0375 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,415,210 Number of Sequences: 36641 Number of extensions: 426280 Number of successful extensions: 5062 Number of sequences better than 10.0: 126 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 84 Number of HSP's that attempted gapping in prelim test: 4897 Number of HSP's gapped (non-prelim): 178 length of query: 369 length of database: 10,336,785 effective HSP length: 98 effective length of query: 271 effective length of database: 6,745,967 effective search space: 1828157057 effective search space used: 1828157057 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.5 bits)