BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04806 (485 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3B8A-X nrPDB 999 0.0 1IG8-A nrPDB 777 0.0 3O1W-A nrPDB 731 0.0 3W0L-A nrPDB 274 6e-74 3HM8-A nrPDB 272 3e-73 5HFU-A nrPDB 266 1e-71 1BG3-A nrPDB 263 1e-70 4FOI-A nrPDB 261 6e-70 4DCH-A nrPDB 258 3e-69 4QS9-A nrPDB 258 6e-69 5ZQT-A nrPDB 253 2e-67 1BDG-A nrPDB 251 4e-67 2YHX-A nrPDB 197 6e-51 1HKG-A nrPDB 194 5e-50 2ROH-A nrPDB 32 0.83 1C01-A nrPDB 31 1.4 1TO3-A nrPDB 30 1.8 2PNF-A nrPDB 30 2.3 3BPV-A nrPDB 29 3.5 4TW1-A nrPDB 29 4.9 5UKG-A nrPDB 28 8.8 >3B8A-X nrPDB Length = 485 Score = 999 bits (2583), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/485 (100%), Positives = 485/485 (100%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG Sbjct: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 Query: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT Sbjct: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 Query: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI Sbjct: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 Query: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF Sbjct: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 Query: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA Sbjct: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 Query: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED Sbjct: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 Query: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV Sbjct: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL 480 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL Sbjct: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL 480 Query: 481 GIIGA 485 GIIGA Sbjct: 481 GIIGA 485 >1IG8-A nrPDB Length = 486 Score = 777 bits (2007), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/486 (77%), Positives = 433/486 (89%), Gaps = 1/486 (0%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 MVHLGPKKPQARKGSMADVPKELM +I E +FTV +ETL+ V KHFI EL KGL+KKG Sbjct: 1 MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKG 60 Query: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 GNIPMIPGWVM+FPTGKESG++LAIDLGGTNLRVVLVKL G+ TFDTTQSKY+LP MRT Sbjct: 61 GNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRT 120 Query: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 T++ +ELW FIADSLK F+ EQ + +PLGFTFS+PASQNKINEGILQRWTKGFDI Sbjct: 121 TQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDI 180 Query: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 PN+E HDVVP+LQ +I+KR +PIE+VALINDT GTL+ASYYTDPETKMGVIFGTGVNGA+ Sbjct: 181 PNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAY 240 Query: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 YDV SDIEKL+GKL+DDIP ++PMAINCEYGSFDNEH+VLPRTKYD+ +DE+SPRPGQQ Sbjct: 241 YDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQT 300 Query: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 FEKM+SGYYLGE+LRL L+++ ++G + K+QDLSK +P++MDTSYPARIE+DPFENLED Sbjct: 301 FEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLED 360 Query: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 TDD+FQ +FG+ TT+ ERKLIRRL ELIG RAARL+VCGIAAICQKRGYKTGHIAADGSV Sbjct: 361 TDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGYKTGHIAADGSV 420 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479 YN+YPGFKE AA L+DIYGWT + D PI IVPAEDGSGAGAAVIAAL++KRIAEGKS Sbjct: 421 YNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKS 480 Query: 480 LGIIGA 485 +GIIGA Sbjct: 481 VGIIGA 486 >3O1W-A nrPDB Length = 485 Score = 731 bits (1886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/485 (71%), Positives = 411/485 (84%), Gaps = 2/485 (0%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 MV LGPKKP ARKGSMADVP LM++IH LE +FTV SE +R +VKHFI EL+KGL+KKG Sbjct: 1 MVRLGPKKPPARKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG 60 Query: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 GNIPMIPGWV+E+PTGKE+G++LA+DLGGTNLRVVLVKL GNH FDTTQ+KY+LP +RT Sbjct: 61 GNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRT 120 Query: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 E+LWSFIA LK+F+ E + LPLGFTFSYPASQ KIN G+LQRWTKGFDI Sbjct: 121 GT-SEQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDI 179 Query: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 VEGHDVVP+LQ +I K +PI +VALINDT GTL+AS YTDP+TKMG+I GTGVNGA+ Sbjct: 180 EGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAY 239 Query: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 YDVVS IEKLEG L +DI +SPMAINCEYGSFDNEHLVLPRTKYDV +DE+SPRPGQQA Sbjct: 240 YDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQA 299 Query: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 FEKMTSGYYLGE++RLVLL+L + G + KDQD+SKLK+ Y+MDTSYP++IEDDPFENLED Sbjct: 300 FEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLED 359 Query: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 TDD+F+ + ++TT+ ERKLIR+L EL+GTRAARL VCG++AIC KRGYKT HIAADGSV Sbjct: 360 TDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSV 419 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479 +N+YPG+KE AA+ L+DIY W + +D PI +V AEDGSG GAA+IA L++KR+A GKS Sbjct: 420 FNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGKS 479 Query: 480 LGIIG 484 +GI G Sbjct: 480 VGIKG 484 >3W0L-A nrPDB Length = 458 Score = 274 bits (701), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 164/463 (35%), Positives = 259/463 (55%), Gaps = 33/463 (7%) Query: 25 DEIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGN 81 +E+ Q+ F + E L ++ E+ +GL T + ++ M+P +V P G E G+ Sbjct: 7 NEVDQILSEFHLQEEDLHVLMCRMQAEMERGLHLETNEEASVKMLPTYVRSTPDGSEVGD 66 Query: 82 YLAIDLGGTNLRVVLVK----LSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKD 137 +LA+DLGGTN RV+LVK L G +T Y +P D T E L+ +IA+ + D Sbjct: 67 FLALDLGGTNFRVMLVKVGEDLEGQWKVETKHKMYSIPVDAMTGT-AEMLFDYIAECISD 125 Query: 138 FMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEIS 197 ++ +Q + + K LPLGFTFS+P I++GIL WTKGF EG++VV LL++ I Sbjct: 126 YLDQQNMKHKK--LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIK 183 Query: 198 KR-ELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLAD 256 +R + +++VA++NDTV T+I+ YY D ++G+I GTG N + + +S++E +EG+ Sbjct: 184 RRGDFEMDVVAMVNDTVATMISCYYEDHHCEVGLIVGTGCNACYMEEMSNVELVEGE--- 240 Query: 257 DIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLR 315 M +N E+G+F D L R +YD VDE S PGQQ +EKM G Y+GEL+R Sbjct: 241 ----EGRMCVNTEWGAFGDTGELEDFRLEYDRVVDEASLNPGQQLYEKMIGGKYMGELVR 296 Query: 316 LVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTL 375 LVL+++ + L+ + KLK +T + ++IE D + + T +I + GV+ T+ Sbjct: 297 LVLIKMVNENLLFGGESSEKLKTRGAFETQFVSQIEADT-SDFKQTLNIL-RTLGVQATI 354 Query: 376 PERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGH------IAADGSVYNKYPGFKE 429 + +R CE + TRAA + G+A I + + DGSVY +P FK+ Sbjct: 355 GDCHAVRLACESVSTRAAIMCSAGLAGILNRMRQSRREELLRITVGVDGSVYKLHPSFKD 414 Query: 430 AAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEK 472 + + S IT + +E+GSG GAA+I+A++ K Sbjct: 415 KFHATVLKL------TSGCEITFIQSEEGSGRGAALISAVAYK 451 >3HM8-A nrPDB Length = 445 Score = 272 bits (695), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 153/447 (34%), Positives = 253/447 (56%), Gaps = 28/447 (6%) Query: 34 FTVDSETLRKVVKHFIDELNKGLTKKGGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLR 93 F ++ + L V + KGL + ++ M+P +V P G E G++LA+DLGGTN R Sbjct: 13 FRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSERGDFLALDLGGTNFR 72 Query: 94 VVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPL 153 V+LV+++ T Y +P + Q+ L+ I D + DF +Q L + +LPL Sbjct: 73 VLLVRVTTG--VQITSEIYSIPETVAQGSGQQ-LFDHIVDCIVDFQQKQGL--SGQSLPL 127 Query: 154 GFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRE-LPIEIVALINDT 212 GFTFS+P Q +++GIL WTKGF + EG DVV LL+ I++R+ + + +VA++NDT Sbjct: 128 GFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDT 187 Query: 213 VGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGS 272 VGT+++ Y DP ++G+I GTG N + + + ++ + G + M IN E+G+ Sbjct: 188 VGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPG-------DSGRMCINMEWGA 240 Query: 273 F-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQ 331 F D+ L + T++D +VD+ S PG+Q FEKM SG YLGE++R +LL L G++ + Q Sbjct: 241 FGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQ 300 Query: 332 DLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTR 391 + +L+ I T + + IE D L I + D G+ T + ++ +C+ + R Sbjct: 301 QIQRLQTRDIFKTKFLSEIESDSLA-LRQVRAILE-DLGLPLTSDDALMVLEVCQAVSQR 358 Query: 392 AARLAVCGIAAICQK----RGYK--TGHIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDA 445 AA+L G+AA+ +K RG + + DG++Y +P F A +R++ A Sbjct: 359 AAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVREL------A 412 Query: 446 SKDPITIVPAEDGSGAGAAVIAALSEK 472 + +T + +EDGSG GAA++ A++ + Sbjct: 413 PRCVVTFLQSEDGSGKGAALVTAVACR 439 >5HFU-A nrPDB Length = 923 Score = 266 bits (681), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 157/447 (35%), Positives = 258/447 (57%), Gaps = 35/447 (7%) Query: 39 ETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVV 95 + L +V + E+ +GL+K+ + M+P +V P G E G++LA+DLGGTN RV+ Sbjct: 488 DQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVL 547 Query: 96 LVKLSGNH--TFDTTQSKYKLPHD-MRTTKHQEELWSFIADSLKDFMVEQELLNTKD-TL 151 LV++ + Y +P + M T +EL+ I + DF+ E + K +L Sbjct: 548 LVRVRNGKWGGVEMHNKIYAIPQEVMHGTG--DELFDHIVQCIADFL---EYMGMKGVSL 602 Query: 152 PLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRE-LPIEIVALIN 210 PLGFTFS+P QN ++E IL +WTKGF EG DVV LL+ I +RE +++VA++N Sbjct: 603 PLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVN 662 Query: 211 DTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEY 270 DTVGT++ + DP ++G+I GTG N + + + ++E +EG+ M +N E+ Sbjct: 663 DTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGE-------EGRMCVNMEW 715 Query: 271 GSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLK 329 G+F DN L RT++DVAVDE S PG+Q FEKM SG YLGE++R +L++ ++GL+ + Sbjct: 716 GAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFR 775 Query: 330 DQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIG 389 + +LK I +T + ++IE D L+ I Q G+++T + +++ +C ++ Sbjct: 776 GRISERLKTRGIFETKFLSQIESDCLALLQ-VRAILQH-LGLESTCDDSIIVKEVCTVVA 833 Query: 390 TRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEAAAKGLRDIYGWTG 443 RAA+L G+AA+ + G + DG++Y +P F + + ++D+ Sbjct: 834 RRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDL----- 888 Query: 444 DASKDPITIVPAEDGSGAGAAVIAALS 470 A K ++ + +EDGSG GAA+I A++ Sbjct: 889 -APKCDVSFLQSEDGSGKGAALITAVA 914 Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 162/452 (35%), Positives = 246/452 (54%), Gaps = 45/452 (9%) Query: 39 ETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVV 95 ETL ++ K F E+ KGL T + M+P +V P G E G +LA+DLGGTN RV+ Sbjct: 40 ETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVL 99 Query: 96 LVKLSGN--HTFDTTQSKYKLPHD-MRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLP 152 VK++ N + Y +P D MR + Q L+ IA+ L +FM + ++ + K LP Sbjct: 100 WVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQ--LFDHIAECLANFMDKLQIKDKK--LP 155 Query: 153 LGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR-ELPIEIVALIND 211 LGFTFS+P Q K++E L WTKGF VEG DVV L++ I +R + I+IVA++ND Sbjct: 156 LGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVND 215 Query: 212 TVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYG 271 TVGT++ Y D ++G+I GTG N + + + I+ +EG M IN E+G Sbjct: 216 TVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG-------DEGRMCINMEWG 268 Query: 272 SF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKD 330 +F D+ L RT++D +D S PG+Q FEKM SG Y+GEL+RL+L+++ ++ L+ Sbjct: 269 AFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFG- 327 Query: 331 QDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQK------DFGVKTTLPERKLIRRL 384 KL P +++T R E ++E D +K G+ T + R+ Sbjct: 328 ---GKL-SPELLNT---GRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRI 380 Query: 385 CELIGTRAARLAVCGIAAICQKRGYKTGH------IAADGSVYNKYPGFKEAAAKGLRDI 438 C+++ TR+A L +AA+ Q+ G I DGSVY K+P F + K +R + Sbjct: 381 CQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRL 440 Query: 439 YGWTGDASKDPITIVPAEDGSGAGAAVIAALS 470 + + +EDGSG GAA++ A++ Sbjct: 441 VPGC------DVRFLRSEDGSGKGAAMVTAVA 466 >1BG3-A nrPDB Length = 918 Score = 263 bits (673), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 162/469 (34%), Positives = 262/469 (55%), Gaps = 38/469 (8%) Query: 19 VPKELMDEIHQLEDM---FTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVME 72 V L ++ Q+E+ F + +TL +V K E+ GL T + M+P +V Sbjct: 459 VAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSFVRS 518 Query: 73 FPTGKESGNYLAIDLGGTNLRVVLVKLSG--NHTFDTTQSKYKLPHD-MRTTKHQEELWS 129 P G E G++LA+DLGGTN RV+LVK+ T + Y +P + M+ T +EL+ Sbjct: 519 IPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTG--DELFD 576 Query: 130 FIADSLKDFMVEQELLNTKD-TLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDV 188 I + DF+ + + K +PLGFTFS+P Q ++ GIL WTKGF + EGHDV Sbjct: 577 HIVSCISDFL---DYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEGHDV 633 Query: 189 VPLLQNEISKRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDI 247 LL++ + +RE +++VA++NDTVGT++ Y +P ++G+I GTG N + + + ++ Sbjct: 634 ASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEMKNV 693 Query: 248 EKLEGKLADDIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTS 306 E +EG + M IN E+G+F DN L RT +D VDE S G+Q FEKM S Sbjct: 694 EMVEG-------NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMIS 746 Query: 307 GYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQ 366 G YLGE++R +L++ +KG + + Q LK I +T + ++IE D L+ I Q Sbjct: 747 GMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQ-VRAILQ 805 Query: 367 KDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQK----RG--YKTGHIAADGSV 420 + G+ +T + L++ +C ++ RAA+L G+AA+ +K RG + + DG++ Sbjct: 806 Q-LGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTL 864 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAAL 469 Y +P F + ++++ + K ++ + +EDGSG GAA+I A+ Sbjct: 865 YKLHPHFSRIMHQTVKEL------SPKCTVSFLLSEDGSGKGAALITAV 907 Score = 226 bits (575), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 144/451 (31%), Positives = 241/451 (53%), Gaps = 32/451 (7%) Query: 39 ETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVV 95 E L ++ F E+ GL++ ++ M+P +V P G E G+++A+DLGG++ R++ Sbjct: 34 EILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRIL 93 Query: 96 LVKLS--GNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPL 153 V+++ N Y P ++ +L+ +AD L DFM ++ LP+ Sbjct: 94 RVQVNHEKNQNVSMESEIYDTPENI-VHGSGTQLFDHVADCLGDFM--EKKKIKDKKLPV 150 Query: 154 GFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR-ELPIEIVALINDT 212 GFTFS+P Q+KI+E +L WTK F VEG DVV LL I KR + IVA++NDT Sbjct: 151 GFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDT 210 Query: 213 VGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGS 272 VGT++ Y D + ++G+I GTG N + + + I+ +EG M IN E+G+ Sbjct: 211 VGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEG-------DEGRMCINTEWGA 263 Query: 273 F-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQ 331 F D+ L RT++D +D S PG+Q FEKM SG Y+GEL+RL+L+++ ++GL+ + + Sbjct: 264 FGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGR 323 Query: 332 DLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTR 391 +L +TS + IE D E +++ +I + GV+ + + ++ +C ++ R Sbjct: 324 ITPELLTRGKFNTSDVSAIEKDK-EGIQNAKEILTR-LGVEPSDVDCVSVQHICTIVSFR 381 Query: 392 AARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDA 445 +A L + AI + G + DGS+Y +P + K LR + Sbjct: 382 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRL------V 435 Query: 446 SKDPITIVPAEDGSGAGAAVIAALSEKRIAE 476 + + +E G+G GAA++ A++ R+AE Sbjct: 436 PDSDVRFLLSESGTGKGAAMVTAVA-YRLAE 465 >4FOI-A nrPDB Length = 917 Score = 261 bits (666), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 165/479 (34%), Positives = 263/479 (54%), Gaps = 38/479 (7%) Query: 19 VPKELMDEIHQLEDM---FTVDSETLRKVVKHFIDELNKGLTKKGGN---IPMIPGWVME 72 V L ++ Q+E+ F + + L +V K E+ GL K+ N + M+P +V Sbjct: 459 VAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRR 518 Query: 73 FPTGKESGNYLAIDLGGTNLRVVLVKLSG--NHTFDTTQSKYKLPHD-MRTTKHQEELWS 129 P G E+G++LA+DLGGTN RV+LVK+ T + Y +P + M+ T EEL+ Sbjct: 519 TPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTG--EELFD 576 Query: 130 FIADSLKDFMVEQELLNTKD-TLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDV 188 I + DF+ + + K +PLGFTFS+P Q ++ GIL WTKGF + GHDV Sbjct: 577 HIVSCISDFL---DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDV 633 Query: 189 VPLLQNEISKRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDI 247 V LL++ I +RE +++VA++NDTVGT++ Y +P ++G+I GTG N + + + ++ Sbjct: 634 VTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNV 693 Query: 248 EKLEGKLADDIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTS 306 E +EG M IN E+G+F DN L RT YD VDE S G+Q +EKM S Sbjct: 694 EMVEG-------DQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMIS 746 Query: 307 GYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQ 366 G YLGE++R +L++ +KG + + Q LK I +T + ++IE D L+ I Q Sbjct: 747 GMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQ-VRAILQ 805 Query: 367 KDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSV 420 + G+ +T + L++ +C ++ RAA+L G+AA+ K G + DG++ Sbjct: 806 Q-LGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTL 864 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479 Y +P F + ++++ + K ++ + +EDGSG GAA+I A+ + E S Sbjct: 865 YKLHPHFSRIMHQTVKEL------SPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 917 Score = 229 bits (584), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 147/451 (32%), Positives = 243/451 (53%), Gaps = 32/451 (7%) Query: 39 ETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVV 95 ETL ++ F E+ GL++ + M+P +V P G E G+++A+DLGG++ R++ Sbjct: 34 ETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRIL 93 Query: 96 LVKLS--GNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPL 153 V+++ N Y P ++ +L+ +A+ L DFM ++++ + K LP+ Sbjct: 94 RVQVNHEKNQNVHMESEVYDTPENI-VHGSGSQLFDHVAECLGDFMEKRKIKDKK--LPV 150 Query: 154 GFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR-ELPIEIVALINDT 212 GFTFS+P Q+KI+E IL WTK F VEG DVV LL I KR + IVA++NDT Sbjct: 151 GFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDT 210 Query: 213 VGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGS 272 VGT++ Y D ++G+I GTG N + + + I+ +EG M IN E+G+ Sbjct: 211 VGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG-------DEGRMCINTEWGA 263 Query: 273 F-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQ 331 F D+ L RT++D +D S PG+Q FEKM SG YLGEL+RL+L+++ ++GL+ + + Sbjct: 264 FGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGR 323 Query: 332 DLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTR 391 +L +TS + IE + E L + +I + GV+ + + ++ +C ++ R Sbjct: 324 ITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEILTR-LGVEPSDDDCVSVQHVCTIVSFR 381 Query: 392 AARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDA 445 +A L + AI + G + +GS+Y +P + K LR + Sbjct: 382 SANLVAATLGAILNRLRDNKGTPRLRTTVGVNGSLYKTHPQYSRRFHKTLRRL------V 435 Query: 446 SKDPITIVPAEDGSGAGAAVIAALSEKRIAE 476 + + +E GSG GAA++ A++ R+AE Sbjct: 436 PDSDVRFLLSESGSGKGAAMVTAVA-YRLAE 465 >4DCH-A nrPDB Length = 473 Score = 258 bits (660), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 156/466 (33%), Positives = 261/466 (56%), Gaps = 37/466 (7%) Query: 25 DEIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGN 81 +++ Q+ F + E L+KV++ E+++GL T + ++ M+P +V P G E G+ Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73 Query: 82 YLAIDLGGTNLRVVLVKL----SGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKD 137 +L++DLGGTN RV+LVK+ G + T Y +P D T E L+ +I++ + D Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDA-MTGTAEMLFDYISECISD 132 Query: 138 FMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEIS 197 F+ + ++ + K LPLGFTFS+P I++GIL WTKGF EG++VV LL++ I Sbjct: 133 FLDKHQMKHKK--LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIK 190 Query: 198 KR-ELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLAD 256 +R + +++VA++NDTV T+I+ YY D + ++G+I GTG N + + + ++E +EG Sbjct: 191 RRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG---- 246 Query: 257 DIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLR 315 M +N E+G+F D+ L +YD VDE S PGQQ +EK+ G Y+GEL+R Sbjct: 247 ---DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVR 303 Query: 316 LVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQ--KDFGVKT 373 LVLL L ++ L+ + +L+ +T + +++E D D I+ G++ Sbjct: 304 LVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDT----GDRKQIYNILSTLGLRP 359 Query: 374 TLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGH------IAADGSVYNKYPGF 427 + + ++RR CE + TRAA + G+A + + + DGSVY +P F Sbjct: 360 STTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF 419 Query: 428 KEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKR 473 KE +R + IT + +E+GSG GAA+++A++ K+ Sbjct: 420 KERFHASVRRL------TPSCEITFIESEEGSGRGAALVSAVACKK 459 >4QS9-A nrPDB Length = 474 Score = 258 bits (658), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 163/444 (36%), Positives = 235/444 (52%), Gaps = 27/444 (6%) Query: 41 LRKVVKHFIDELNKGLTKKGGN-IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKL 99 LR+V E++ GL GG+ + M+ +V P+G E G + A+DLGGTN RV+ V L Sbjct: 33 LRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKGLFYALDLGGTNFRVMRVLL 92 Query: 100 SGNHTFDTTQSKYKL---PHDMRTTKHQEELWSFIADSLKDFM---VEQELLNTKDTLPL 153 G Q ++ PH M T +EL++FIA++L F+ E L L Sbjct: 93 GGKQERVVKQEFEEVSIPPHLM--TGGSDELFNFIAEALAKFVATECEDFHLPEGRQREL 150 Query: 154 GFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRELPIEIVALINDTV 213 GFTF++P Q ++ G L +WTKGF I G DVV L + + L + I AL+NDTV Sbjct: 151 GFTFAFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGALNKALERVGLDMRIAALVNDTV 210 Query: 214 GTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSF 273 GTL Y +P+ VI GTG N A+ + + I K G L P + M IN E+G+F Sbjct: 211 GTLAGGRYYNPDVVAAVILGTGTNAAYVERATAIPKWHGLL----PKSGEMVINMEWGNF 266 Query: 274 DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDL 333 + H LP T++D +D +S PG+Q EK+ SG YLGE+LR VLL++ E D Sbjct: 267 RSSH--LPLTEFDHTLDFESLNPGEQILEKIISGMYLGEILRRVLLKMAEDAAFFGDTVP 324 Query: 334 SKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTT-LPERKLIRRLCELIGTRA 392 SKL+ P+I+ T + + + +D +L+ + V TT L RK++ LC +I TR Sbjct: 325 SKLRIPFIIRTPHMSAMHNDTSPDLKIVGSKIKDILEVPTTSLKMRKVVISLCNIIATRG 384 Query: 393 ARLAVCGIAAICQKRGYKTGH--------IAADGSVYNKYPGFKEAAAKGLRDIYGWTGD 444 ARL+ GI I +K G T IA DG ++ Y F E L+++ GD Sbjct: 385 ARLSAAGIYGILKKLGRDTTKDEEVQKSVIAMDGGLFEHYTQFSECMESSLKELL---GD 441 Query: 445 ASKDPITIVPAEDGSGAGAAVIAA 468 + + + + DGSG GAA++AA Sbjct: 442 EASGSVEVTHSNDGSGIGAALLAA 465 >5ZQT-A nrPDB Length = 473 Score = 253 bits (645), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 163/460 (35%), Positives = 238/460 (51%), Gaps = 29/460 (6%) Query: 27 IHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK-GGNIPMIPGWVMEFPTGKESGNYLAI 85 I ++E F+ + LR + ++E+ +GL + M+ +V PTG E G + A+ Sbjct: 16 IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYAL 75 Query: 86 DLGGTNLRVVLVKLSGNHTFDTTQSKYKL---PHDMRTTKHQEELWSFIADSLKDFMV-- 140 DLGGTN RV+ V+L G +Q ++ PH M T EL+ FIA L+ F+ Sbjct: 76 DLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSM--ELFDFIAAELESFVKTE 133 Query: 141 -EQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR 199 E L LGFTFS+P Q I+ G L +WTKGF I G DVV L + ++ Sbjct: 134 GEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ 193 Query: 200 ELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIP 259 L +++ AL+NDTVGTL Y D + VI GTG N A+ + + I K G L P Sbjct: 194 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLL----P 249 Query: 260 SNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLL 319 + M IN E+G+F +E LPR+ YD A+D +S PG+Q +EKM SG YLGE++R +LL Sbjct: 250 RSGNMVINMEWGNFKSER--LPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 307 Query: 320 ELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVK-TTLPER 378 +L + D +KL+Q +I+ T + + D +L+ + GV T+L R Sbjct: 308 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 367 Query: 379 KLIRRLCELIGTRAARLAVCGIAAICQKRGY----------KTGHIAADGSVYNKYPGFK 428 + +C+L+ R ARLA GI I +K G + IA DG +Y Y F+ Sbjct: 368 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 427 Query: 429 EAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAA 468 L D+ G+ + + + A DGSG GAA++AA Sbjct: 428 TCLEATLADLL---GEEAASSVVVKLANDGSGIGAALLAA 464 >1BDG-A nrPDB Length = 451 Score = 251 bits (642), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 160/449 (35%), Positives = 242/449 (53%), Gaps = 23/449 (5%) Query: 26 EIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGNY 82 EI + D+ VD E ++ + + GL T + +I M P +V + P G E+GN+ Sbjct: 14 EILKPFDLSVVDYE---EICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTPNGTETGNF 70 Query: 83 LAIDLGGTNLRVVLVKLSGNHTFDTTQSK-YKLPHDMRTTKHQEELWSFIADSLKDFMVE 141 LA+DLGGTN RV+ V L G Q + Y +P + + + EL+ +IA++L DF+ Sbjct: 71 LALDLGGTNYRVLSVTLEGKGKSPRIQERTYCIPAE-KMSGSGTELFKYIAETLADFLEN 129 Query: 142 QELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKREL 201 + + K LGFTFS+P Q + L RWTKGF VEGH+V LLQ E+ KREL Sbjct: 130 NGMKDKK--FDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQTELDKREL 187 Query: 202 PIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSN 261 ++ VA++NDTVGTL + DP+ +G+I GTG N A+ + S +E ++G ++ Sbjct: 188 NVKCVAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGVKEPEV--- 244 Query: 262 SPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLE 320 IN E+G+F + L RT++D ++D S PG+Q +EKM SG YLGEL+R +++ Sbjct: 245 ---VINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRHIIVY 301 Query: 321 LNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLP-ERK 379 L E+ ++ + +LK + T Y +E DP L +T + D V P + + Sbjct: 302 LVEQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHLLYNTHYMLTDDLHVPVVEPIDNR 361 Query: 380 LIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYNKYPGFKEAAAKGLRDIY 439 ++R CE++ RAA LA GIA I ++ + DGS+Y +P F E + + Sbjct: 362 IVRYACEMVVKRAAYLAGAGIACILRRINRSEVTVGVDGSLYKFHPKFCERMTDMVDKL- 420 Query: 440 GWTGDASKDPITIVPAEDGSGAGAAVIAA 468 + +EDGSG GAA IAA Sbjct: 421 ----KPKNTRFCLRLSEDGSGKGAAAIAA 445 >2YHX-A nrPDB Length = 457 Score = 197 bits (502), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 132/410 (32%), Positives = 192/410 (46%), Gaps = 10/410 (2%) Query: 63 IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTK 122 IPM+PGWV++ +G ++G++LAI +GG +L V+L+ L+G S+ L M TT Sbjct: 44 IPMVPGWVLKQVSGAQAGSFLAIVMGGGDLEVILISLAGRQESSIXASR-SLAAAMSTTA 102 Query: 123 HQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPN 182 +LW A S E + ++PLGFTF ++ + +G + F + Sbjct: 103 IPSDLWGNXAXS-NAAFSSXEFSSXAGSVPLGFTFXEAGAKEXVIKGQITXQAXAFSLAX 161 Query: 183 VEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYD 242 + ++ + N VA I D+ G L YTD KMG+IFG+GVN A++ Sbjct: 162 LX--KLISAMXNAXFPAGDXXXSVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAYWC 219 Query: 243 VVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFE 302 + I M I C+ SF LP+ Y ++ SP + F Sbjct: 220 DSTXIGDAADGGXXG--GAGXMXICCDQSSFRKAFPSLPQIXYLXTLNXXSPX-AXKTFX 276 Query: 303 KMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTD 362 K + G+ LR VL+ G + +TSYPA+I+ P +L Sbjct: 277 KNSXAKNXGQSLRDVLMXFKXXG-QXHXXXAXSFXAANVENTSYPAKIQKLPHFDLRXXX 335 Query: 363 DIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYN 422 D+F D G+ + ++RR LI A RL VC I AICQK+GY +GHIAA GS Sbjct: 336 DLFXGDQGIAXKTXMKXVVRRXLFLIAAYAFRLVVCXIXAICQKKGYSSGHIAAXGSX-R 394 Query: 423 KYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSE 471 Y GF +A +IYGW A PI I PA DG GA + VI +++ Sbjct: 395 SYSGFSXNSATXNXNIYGWPQSAXXSKPIXITPAIDGXGAASXVIXSIAS 444 >1HKG-A nrPDB Length = 457 Score = 194 bits (494), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 131/412 (31%), Positives = 192/412 (46%), Gaps = 10/412 (2%) Query: 63 IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTK 122 IPM+PGWV++ G ++G++LAI +GG +L V+L+ L+G S+ L M TT Sbjct: 44 IPMVPGWVLKQVXGSQAGSFLAIVMGGGDLEVILIXLAGYQESSIXASR-SLAASMXTTA 102 Query: 123 HQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPN 182 +LW A S E + ++PLGFTF ++ + +G + F + Sbjct: 103 IPSDLWGNXAXS-NAAFSSXEFSSXAGSVPLGFTFXEAGAKEXVIKGQITXQAXAFSLAX 161 Query: 183 VEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYD 242 + ++ + N VA I D+ G L YTD KMG+IFG+GVN A++ Sbjct: 162 LX--KLISAMXNAXFPAGDXXXXVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAYWC 219 Query: 243 VVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFE 302 + I M + C SF LP+ Y ++ SP + FE Sbjct: 220 DSTXIADAADAGXXG--GAGXMXVCCXQDSFRKAFPSLPQIXYXXTLNXXSPX-AXKTFE 276 Query: 303 KMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTD 362 K + G+ LR VL+ G + ++SYPA+I+ P +L Sbjct: 277 KNSXAKNXGQSLRDVLMXYKXXG-QXHXXXAXDFXAANVENSSYPAKIQKLPHFDLRXXX 335 Query: 363 DIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYN 422 D+F D G+ + ++RR LI A RL VC I AICQK+GY +GHIAA GS + Sbjct: 336 DLFXGDQGIAXKTXMKXVVRRXLFLIAAYAFRLVVCXIXAICQKKGYSSGHIAAXGSXRD 395 Query: 423 KYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKR 473 Y GF +A +IYGW A PI I PA DG GA VI +++ + Sbjct: 396 -YSGFSXNSATXNXNIYGWPQSAXXSKPIXITPAIDGEGAAXXVIXSIASSQ 446 >2ROH-A nrPDB Length = 122 Score = 31.6 bits (70), Expect = 0.83, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDS 38 +VH PQ R+G A VP+EL+D + + ++VDS Sbjct: 80 LVHTASIAPQQRRG--APVPQELLDRVLAAQAYWSVDS 115 >1C01-A nrPDB Length = 76 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 391 RAARLAVCGIAAICQKRGYKTGHIAADGSVYNK 423 RA R + CG +AI QK GY + ++YN+ Sbjct: 14 RAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQ 46 >1TO3-A nrPDB Length = 304 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 275 NEHLVLPRTKYDVAVDEQ-SPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDL 333 N H+ +P VDE+ PR + A E SG+ G + ++ L + LML+D Sbjct: 217 NGHINMPWVILSSGVDEKLFPRAVRVAMEAGASGFLAGRAVWSSVIGLPDTELMLRDVSA 276 Query: 334 SKLKQ 338 KL++ Sbjct: 277 PKLQR 281 >2PNF-A nrPDB Length = 248 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 13/48 (27%), Positives = 26/48 (54%) Query: 138 FMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEG 185 + LL+ ++ L + T ++ +QN + + I QRW + +I +V G Sbjct: 100 LFLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIKQRWGRIVNISSVVG 147 >3BPV-A nrPDB Length = 138 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 318 LLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPE 377 L L E G + ++QD ++ + T I + E +D+ +DF T E Sbjct: 64 LRRLEESGFIEREQDPENRRRYILEVTRRGEEIIPLILKVEERWEDLLFRDF----TEDE 119 Query: 378 RKLIRRLCELIGTRAARL 395 RKL R++C + A R+ Sbjct: 120 RKLFRKMCRRLAEEAVRM 137 >4TW1-A nrPDB Length = 311 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 3/72 (4%) Query: 182 NVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFY 241 N GHD L N+ R EI +L + G L A P+ KM V G N F Sbjct: 178 NNMGHDHTRQLTNDSDNR-TKSEIFSLTRN--GNLWAKDNFTPKDKMPVTVSEGFNPEFL 234 Query: 242 DVVSDIEKLEGK 253 V+S +K +GK Sbjct: 235 AVMSHDKKDKGK 246 >5UKG-A nrPDB Length = 419 Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 271 GSFD-NEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLK 329 G+FD E L + K V E+ R + F+K +GY LR V+ +L EK L Sbjct: 332 GTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEK---LT 388 Query: 330 DQDLSKL 336 D+++ ++ Sbjct: 389 DEEVDEM 395 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3B8A-X nrPDB 717 0.0 1IG8-A nrPDB 686 0.0 3O1W-A nrPDB 680 0.0 4FOI-A nrPDB 576 e-165 1BG3-A nrPDB 570 e-163 5HFU-A nrPDB 563 e-161 3W0L-A nrPDB 550 e-157 4DCH-A nrPDB 526 e-150 3HM8-A nrPDB 526 e-150 1BDG-A nrPDB 519 e-147 5ZQT-A nrPDB 504 e-143 4QS9-A nrPDB 492 e-139 2YHX-A nrPDB 352 2e-97 1HKG-A nrPDB 339 2e-93 Sequences not found previously or not previously below threshold: 2FEZ-A nrPDB 31 1.4 5CY4-A nrPDB 30 2.0 4BAX-A nrPDB 30 2.3 6EMK-G nrPDB 30 2.7 6CE1-A nrPDB 29 5.0 1WZC-A nrPDB 28 7.4 4W8B-A nrPDB 28 7.7 6MSK-b nrPDB 28 8.6 CONVERGED! >3B8A-X nrPDB Length = 485 Score = 717 bits (1851), Expect = 0.0, Method: Composition-based stats. Identities = 485/485 (100%), Positives = 485/485 (100%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG Sbjct: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 Query: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT Sbjct: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 Query: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI Sbjct: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 Query: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF Sbjct: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 Query: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA Sbjct: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 Query: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED Sbjct: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 Query: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV Sbjct: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL 480 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL Sbjct: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL 480 Query: 481 GIIGA 485 GIIGA Sbjct: 481 GIIGA 485 >1IG8-A nrPDB Length = 486 Score = 686 bits (1771), Expect = 0.0, Method: Composition-based stats. Identities = 376/486 (77%), Positives = 433/486 (89%), Gaps = 1/486 (0%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 MVHLGPKKPQARKGSMADVPKELM +I E +FTV +ETL+ V KHFI EL KGL+KKG Sbjct: 1 MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKG 60 Query: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 GNIPMIPGWVM+FPTGKESG++LAIDLGGTNLRVVLVKL G+ TFDTTQSKY+LP MRT Sbjct: 61 GNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRT 120 Query: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 T++ +ELW FIADSLK F+ EQ + +PLGFTFS+PASQNKINEGILQRWTKGFDI Sbjct: 121 TQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDI 180 Query: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 PN+E HDVVP+LQ +I+KR +PIE+VALINDT GTL+ASYYTDPETKMGVIFGTGVNGA+ Sbjct: 181 PNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAY 240 Query: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 YDV SDIEKL+GKL+DDIP ++PMAINCEYGSFDNEH+VLPRTKYD+ +DE+SPRPGQQ Sbjct: 241 YDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQT 300 Query: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 FEKM+SGYYLGE+LRL L+++ ++G + K+QDLSK +P++MDTSYPARIE+DPFENLED Sbjct: 301 FEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLED 360 Query: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 TDD+FQ +FG+ TT+ ERKLIRRL ELIG RAARL+VCGIAAICQKRGYKTGHIAADGSV Sbjct: 361 TDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGYKTGHIAADGSV 420 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479 YN+YPGFKE AA L+DIYGWT + D PI IVPAEDGSGAGAAVIAAL++KRIAEGKS Sbjct: 421 YNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKS 480 Query: 480 LGIIGA 485 +GIIGA Sbjct: 481 VGIIGA 486 >3O1W-A nrPDB Length = 485 Score = 680 bits (1756), Expect = 0.0, Method: Composition-based stats. Identities = 345/485 (71%), Positives = 411/485 (84%), Gaps = 2/485 (0%) Query: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60 MV LGPKKP ARKGSMADVP LM++IH LE +FTV SE +R +VKHFI EL+KGL+KKG Sbjct: 1 MVRLGPKKPPARKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG 60 Query: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120 GNIPMIPGWV+E+PTGKE+G++LA+DLGGTNLRVVLVKL GNH FDTTQ+KY+LP +R Sbjct: 61 GNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLR- 119 Query: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180 T E+LWSFIA LK+F+ E + LPLGFTFSYPASQ KIN G+LQRWTKGFDI Sbjct: 120 TGTSEQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDI 179 Query: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240 VEGHDVVP+LQ +I K +PI +VALINDT GTL+AS YTDP+TKMG+I GTGVNGA+ Sbjct: 180 EGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAY 239 Query: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300 YDVVS IEKLEG L +DI +SPMAINCEYGSFDNEHLVLPRTKYDV +DE+SPRPGQQA Sbjct: 240 YDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQA 299 Query: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360 FEKMTSGYYLGE++RLVLL+L + G + KDQD+SKLK+ Y+MDTSYP++IEDDPFENLED Sbjct: 300 FEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLED 359 Query: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420 TDD+F+ + ++TT+ ERKLIR+L EL+GTRAARL VCG++AIC KRGYKT HIAADGSV Sbjct: 360 TDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSV 419 Query: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479 +N+YPG+KE AA+ L+DIY W + +D PI +V AEDGSG GAA+IA L++KR+A GKS Sbjct: 420 FNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGKS 479 Query: 480 LGIIG 484 +GI G Sbjct: 480 VGIKG 484 >4FOI-A nrPDB Length = 917 Score = 576 bits (1485), Expect = e-165, Method: Composition-based stats. Identities = 163/478 (34%), Positives = 260/478 (54%), Gaps = 36/478 (7%) Query: 19 VPKELMDEIHQLEDM---FTVDSETLRKVVKHFIDELNKGLTKKGGN---IPMIPGWVME 72 V L ++ Q+E+ F + + L +V K E+ GL K+ N + M+P +V Sbjct: 459 VAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRR 518 Query: 73 FPTGKESGNYLAIDLGGTNLRVVLVKLSG--NHTFDTTQSKYKLPHDMRTTKHQEELWSF 130 P G E+G++LA+DLGGTN RV+LVK+ T + Y +P ++ EEL+ Sbjct: 519 TPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQ-GTGEELFDH 577 Query: 131 IADSLKDFMVEQELLNTKDT-LPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVV 189 I + DF+ + K +PLGFTFS+P Q ++ GIL WTKGF + GHDVV Sbjct: 578 IVSCISDFLD---YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 634 Query: 190 PLLQNEISKRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIE 248 LL++ I +RE +++VA++NDTVGT++ Y +P ++G+I GTG N + + + ++E Sbjct: 635 TLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVE 694 Query: 249 KLEGKLADDIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSG 307 +EG M IN E+G+F DN L RT YD VDE S G+Q +EKM SG Sbjct: 695 MVEG-------DQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISG 747 Query: 308 YYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQK 367 YLGE++R +L++ +KG + + Q LK I +T + ++IE D L+ I Q+ Sbjct: 748 MYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQ-VRAILQQ 806 Query: 368 DFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVY 421 G+ +T + L++ +C ++ RAA+L G+AA+ K G + DG++Y Sbjct: 807 -LGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLY 865 Query: 422 NKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479 +P F + ++++ + K ++ + +EDGSG GAA+I A+ + E S Sbjct: 866 KLHPHFSRIMHQTVKEL------SPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 917 Score = 442 bits (1138), Expect = e-124, Method: Composition-based stats. Identities = 147/466 (31%), Positives = 245/466 (52%), Gaps = 32/466 (6%) Query: 24 MDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESG 80 + +I + + ETL ++ F E+ GL++ + M+P +V P G E G Sbjct: 19 VKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 78 Query: 81 NYLAIDLGGTNLRVVLVKL--SGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDF 138 +++A+DLGG++ R++ V++ N Y P ++ +L+ +A+ L DF Sbjct: 79 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH-GSGSQLFDHVAECLGDF 137 Query: 139 MVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISK 198 M ++++ + K LP+GFTFS+P Q+KI+E IL WTK F VEG DVV LL I K Sbjct: 138 MEKRKIKDKK--LPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKK 195 Query: 199 REL-PIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADD 257 R IVA++NDTVGT++ Y D ++G+I GTG N + + + I+ +EG Sbjct: 196 RGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEG----- 250 Query: 258 IPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRL 316 M IN E+G+F D+ L RT++D +D S PG+Q FEKM SG YLGEL+RL Sbjct: 251 --DEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRL 308 Query: 317 VLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLP 376 +L+++ ++GL+ + + +L +TS + IE + E L + +I + GV+ + Sbjct: 309 ILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEILTR-LGVEPSDD 366 Query: 377 ERKLIRRLCELIGTRAARLAVCGIAAICQKRG------YKTGHIAADGSVYNKYPGFKEA 430 + ++ +C ++ R+A L + AI + + +GS+Y +P + Sbjct: 367 DCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVNGSLYKTHPQYSRR 426 Query: 431 AAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAE 476 K LR + + + +E GSG GAA++ A++ R+AE Sbjct: 427 FHKTLRRLV------PDSDVRFLLSESGSGKGAAMVTAVA-YRLAE 465 >1BG3-A nrPDB Length = 918 Score = 570 bits (1468), Expect = e-163, Method: Composition-based stats. Identities = 159/477 (33%), Positives = 260/477 (54%), Gaps = 36/477 (7%) Query: 19 VPKELMDEIHQLEDM---FTVDSETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVME 72 V L ++ Q+E+ F + +TL +V K E+ GL K+ + M+P +V Sbjct: 459 VAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKATVKMLPSFVRS 518 Query: 73 FPTGKESGNYLAIDLGGTNLRVVLVKLSG--NHTFDTTQSKYKLPHDMRTTKHQEELWSF 130 P G E G++LA+DLGGTN RV+LVK+ T + Y +P ++ +EL+ Sbjct: 519 IPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQ-GTGDELFDH 577 Query: 131 IADSLKDFMVEQELLNTKDT-LPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVV 189 I + DF+ + K +PLGFTFS+P Q ++ GIL WTKGF + EGHDV Sbjct: 578 IVSCISDFLD---YMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFKATDCEGHDVA 634 Query: 190 PLLQNEISKRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIE 248 LL++ + +RE +++VA++NDTVGT++ Y +P ++G+I GTG N + + + ++E Sbjct: 635 SLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGTNACYMEEMKNVE 694 Query: 249 KLEGKLADDIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSG 307 +EG + M IN E+G+F DN L RT +D VDE S G+Q FEKM SG Sbjct: 695 MVEG-------NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISG 747 Query: 308 YYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQK 367 YLGE++R +L++ +KG + + Q LK I +T + ++IE D L+ I Q+ Sbjct: 748 MYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQ-VRAILQQ 806 Query: 368 DFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVY 421 G+ +T + L++ +C ++ RAA+L G+AA+ +K G + DG++Y Sbjct: 807 -LGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLY 865 Query: 422 NKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGK 478 +P F + ++++ + K ++ + +EDGSG GAA+I A+ + + Sbjct: 866 KLHPHFSRIMHQTVKEL------SPKCTVSFLLSEDGSGKGAALITAVGVRLRGDPS 916 Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats. Identities = 144/466 (30%), Positives = 243/466 (52%), Gaps = 32/466 (6%) Query: 24 MDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESG 80 + +I + + E L ++ F E+ GL++ ++ M+P +V P G E G Sbjct: 19 VKKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKG 78 Query: 81 NYLAIDLGGTNLRVVLVKL--SGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDF 138 +++A+DLGG++ R++ V++ N Y P ++ +L+ +AD L DF Sbjct: 79 DFIALDLGGSSFRILRVQVNHEKNQNVSMESEIYDTPENIVH-GSGTQLFDHVADCLGDF 137 Query: 139 MVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISK 198 M ++ LP+GFTFS+P Q+KI+E +L WTK F VEG DVV LL I K Sbjct: 138 MEKK--KIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKK 195 Query: 199 REL-PIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADD 257 R IVA++NDTVGT++ Y D + ++G+I GTG N + + + I+ +EG Sbjct: 196 RGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEG----- 250 Query: 258 IPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRL 316 M IN E+G+F D+ L RT++D +D S PG+Q FEKM SG Y+GEL+RL Sbjct: 251 --DEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRL 308 Query: 317 VLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLP 376 +L+++ ++GL+ + + +L +TS + IE D E +++ +I + GV+ + Sbjct: 309 ILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKDK-EGIQNAKEILTR-LGVEPSDV 366 Query: 377 ERKLIRRLCELIGTRAARLAVCGIAAICQKRG------YKTGHIAADGSVYNKYPGFKEA 430 + ++ +C ++ R+A L + AI + + DGS+Y +P + Sbjct: 367 DCVSVQHICTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRR 426 Query: 431 AAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAE 476 K LR + + + +E G+G GAA++ A++ R+AE Sbjct: 427 FHKTLRRLV------PDSDVRFLLSESGTGKGAAMVTAVA-YRLAE 465 >5HFU-A nrPDB Length = 923 Score = 563 bits (1451), Expect = e-161, Method: Composition-based stats. Identities = 158/476 (33%), Positives = 266/476 (55%), Gaps = 34/476 (7%) Query: 19 VPKELMDEIH---QLEDMFTVDSETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVME 72 V L D+ + + + + L +V + E+ +GL+K+ + M+P +V Sbjct: 465 VAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCA 524 Query: 73 FPTGKESGNYLAIDLGGTNLRVVLVKLS-GNHT-FDTTQSKYKLPHDMRTTKHQEELWSF 130 P G E G++LA+DLGGTN RV+LV++ G + Y +P ++ +EL+ Sbjct: 525 TPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEV-MHGTGDELFDH 583 Query: 131 IADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVP 190 I + DF+ + +LPLGFTFS+P QN ++E IL +WTKGF EG DVV Sbjct: 584 IVQCIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVT 641 Query: 191 LLQNEISKRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEK 249 LL+ I +RE +++VA++NDTVGT++ + DP ++G+I GTG N + + + ++E Sbjct: 642 LLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVEL 701 Query: 250 LEGKLADDIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGY 308 +EG+ M +N E+G+F DN L RT++DVAVDE S PG+Q FEKM SG Sbjct: 702 VEGE-------EGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGM 754 Query: 309 YLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKD 368 YLGE++R +L++ ++GL+ + + +LK I +T + ++IE D L+ I Q Sbjct: 755 YLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRAILQH- 812 Query: 369 FGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYN 422 G+++T + +++ +C ++ RAA+L G+AA+ + G + DG++Y Sbjct: 813 LGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYK 872 Query: 423 KYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGK 478 +P F + + ++D+ A K ++ + +EDGSG GAA+I A++ + G+ Sbjct: 873 LHPHFAKVMHETVKDL------APKCDVSFLQSEDGSGKGAALITAVACRIREAGQ 922 Score = 471 bits (1211), Expect = e-133, Method: Composition-based stats. Identities = 155/462 (33%), Positives = 247/462 (53%), Gaps = 31/462 (6%) Query: 24 MDEIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESG 80 + ++ Q + ETL ++ K F E+ KGL T + M+P +V P G E G Sbjct: 25 VQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHG 84 Query: 81 NYLAIDLGGTNLRVVLVKLS--GNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDF 138 +LA+DLGGTN RV+ VK++ G + Y +P D+ +L+ IA+ L +F Sbjct: 85 EFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDI-MRGSGTQLFDHIAECLANF 143 Query: 139 MVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISK 198 M + ++ + K LPLGFTFS+P Q K++E L WTKGF VEG DVV L++ I + Sbjct: 144 MDKLQIKDKK--LPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQR 201 Query: 199 RE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADD 257 R I+IVA++NDTVGT++ Y D ++G+I GTG N + + + I+ +EG Sbjct: 202 RGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEG----- 256 Query: 258 IPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRL 316 M IN E+G+F D+ L RT++D +D S PG+Q FEKM SG Y+GEL+RL Sbjct: 257 --DEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRL 314 Query: 317 VLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLP 376 +L+++ ++ L+ + +L +T + IE + + + + + G+ T Sbjct: 315 ILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMR--LGLDPTQE 372 Query: 377 ERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEA 430 + R+C+++ TR+A L +AA+ Q+ G I DGSVY K+P F + Sbjct: 373 DCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKR 432 Query: 431 AAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEK 472 K +R + + + +EDGSG GAA++ A++ + Sbjct: 433 LHKTVRRLV------PGCDVRFLRSEDGSGKGAAMVTAVAYR 468 >3W0L-A nrPDB Length = 458 Score = 550 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 164/463 (35%), Positives = 258/463 (55%), Gaps = 33/463 (7%) Query: 25 DEIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGN 81 +E+ Q+ F + E L ++ E+ +GL T + ++ M+P +V P G E G+ Sbjct: 7 NEVDQILSEFHLQEEDLHVLMCRMQAEMERGLHLETNEEASVKMLPTYVRSTPDGSEVGD 66 Query: 82 YLAIDLGGTNLRVVLVK----LSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKD 137 +LA+DLGGTN RV+LVK L G +T Y +P D T E L+ +IA+ + D Sbjct: 67 FLALDLGGTNFRVMLVKVGEDLEGQWKVETKHKMYSIPVDA-MTGTAEMLFDYIAECISD 125 Query: 138 FMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEIS 197 ++ +Q + + K LPLGFTFS+P I++GIL WTKGF EG++VV LL++ I Sbjct: 126 YLDQQNMKHKK--LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIK 183 Query: 198 KRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLAD 256 +R +++VA++NDTV T+I+ YY D ++G+I GTG N + + +S++E +EG+ Sbjct: 184 RRGDFEMDVVAMVNDTVATMISCYYEDHHCEVGLIVGTGCNACYMEEMSNVELVEGE--- 240 Query: 257 DIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLR 315 M +N E+G+F D L R +YD VDE S PGQQ +EKM G Y+GEL+R Sbjct: 241 ----EGRMCVNTEWGAFGDTGELEDFRLEYDRVVDEASLNPGQQLYEKMIGGKYMGELVR 296 Query: 316 LVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTL 375 LVL+++ + L+ + KLK +T + ++IE D + + T +I + GV+ T+ Sbjct: 297 LVLIKMVNENLLFGGESSEKLKTRGAFETQFVSQIEADTS-DFKQTLNIL-RTLGVQATI 354 Query: 376 PERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKE 429 + +R CE + TRAA + G+A I + + DGSVY +P FK+ Sbjct: 355 GDCHAVRLACESVSTRAAIMCSAGLAGILNRMRQSRREELLRITVGVDGSVYKLHPSFKD 414 Query: 430 AAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEK 472 + + S IT + +E+GSG GAA+I+A++ K Sbjct: 415 KFHATVLKL------TSGCEITFIQSEEGSGRGAALISAVAYK 451 >4DCH-A nrPDB Length = 473 Score = 526 bits (1356), Expect = e-150, Method: Composition-based stats. Identities = 155/464 (33%), Positives = 261/464 (56%), Gaps = 33/464 (7%) Query: 25 DEIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKESGN 81 +++ Q+ F + E L+KV++ E+++GL T + ++ M+P +V P G E G+ Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73 Query: 82 YLAIDLGGTNLRVVLVKLS----GNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKD 137 +L++DLGGTN RV+LVK+ G + T Y +P D T E L+ +I++ + D Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDA-MTGTAEMLFDYISECISD 132 Query: 138 FMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEIS 197 F+ + ++ + K LPLGFTFS+P I++GIL WTKGF EG++VV LL++ I Sbjct: 133 FLDKHQMKHKK--LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIK 190 Query: 198 KRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLAD 256 +R +++VA++NDTV T+I+ YY D + ++G+I GTG N + + + ++E +EG Sbjct: 191 RRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG---- 246 Query: 257 DIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLR 315 M +N E+G+F D+ L +YD VDE S PGQQ +EK+ G Y+GEL+R Sbjct: 247 ---DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVR 303 Query: 316 LVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTL 375 LVLL L ++ L+ + +L+ +T + +++E D + + +I G++ + Sbjct: 304 LVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDT-GDRKQIYNIL-STLGLRPST 361 Query: 376 PERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKE 429 + ++RR CE + TRAA + G+A + + + DGSVY +P FKE Sbjct: 362 TDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKE 421 Query: 430 AAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKR 473 +R + IT + +E+GSG GAA+++A++ K+ Sbjct: 422 RFHASVRRL------TPSCEITFIESEEGSGRGAALVSAVACKK 459 >3HM8-A nrPDB Length = 445 Score = 526 bits (1355), Expect = e-150, Method: Composition-based stats. Identities = 152/454 (33%), Positives = 252/454 (55%), Gaps = 28/454 (6%) Query: 27 IHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKGGNIPMIPGWVMEFPTGKESGNYLAID 86 + + F ++ + L V + KGL + ++ M+P +V P G E G++LA+D Sbjct: 6 LEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSERGDFLALD 65 Query: 87 LGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLN 146 LGGTN RV+LV+++ T Y +P + Q +L+ I D + DF +Q L Sbjct: 66 LGGTNFRVLLVRVTTG--VQITSEIYSIPETVAQGSGQ-QLFDHIVDCIVDFQQKQGLSG 122 Query: 147 TKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRE-LPIEI 205 +LPLGFTFS+P Q +++GIL WTKGF + EG DVV LL+ I++R+ + + + Sbjct: 123 --QSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNV 180 Query: 206 VALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMA 265 VA++NDTVGT+++ Y DP ++G+I GTG N + + + ++ + G + M Sbjct: 181 VAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPG-------DSGRMC 233 Query: 266 INCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEK 324 IN E+G+F D+ L + T++D +VD+ S PG+Q FEKM SG YLGE++R +LL L Sbjct: 234 INMEWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSL 293 Query: 325 GLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRL 384 G++ + Q + +L+ I T + + IE D L I + D G+ T + ++ + Sbjct: 294 GVLFRGQQIQRLQTRDIFKTKFLSEIESDSLA-LRQVRAILE-DLGLPLTSDDALMVLEV 351 Query: 385 CELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEAAAKGLRDI 438 C+ + RAA+L G+AA+ +K G + DG++Y +P F A +R++ Sbjct: 352 CQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVREL 411 Query: 439 YGWTGDASKDPITIVPAEDGSGAGAAVIAALSEK 472 A + +T + +EDGSG GAA++ A++ + Sbjct: 412 ------APRCVVTFLQSEDGSGKGAALVTAVACR 439 >1BDG-A nrPDB Length = 451 Score = 519 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 156/458 (34%), Positives = 245/458 (53%), Gaps = 20/458 (4%) Query: 22 ELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGL---TKKGGNIPMIPGWVMEFPTGKE 78 +L +++ ++ F + ++ + + GL T + +I M P +V + P G E Sbjct: 7 QLFEKVVEILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTPNGTE 66 Query: 79 SGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSK-YKLPHDMRTTKHQEELWSFIADSLKD 137 +GN+LA+DLGGTN RV+ V L G Q + Y +P + + + EL+ +IA++L D Sbjct: 67 TGNFLALDLGGTNYRVLSVTLEGKGKSPRIQERTYCIPAE-KMSGSGTELFKYIAETLAD 125 Query: 138 FMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEIS 197 F+ + + K LGFTFS+P Q + L RWTKGF VEGH+V LLQ E+ Sbjct: 126 FLENNGMKDKK--FDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQTELD 183 Query: 198 KRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADD 257 KREL ++ VA++NDTVGTL + DP+ +G+I GTG N A+ + S +E ++G + Sbjct: 184 KRELNVKCVAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGVKEPE 243 Query: 258 IPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRL 316 + IN E+G+F + L RT++D ++D S PG+Q +EKM SG YLGEL+R Sbjct: 244 V------VINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRH 297 Query: 317 VLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLP 376 +++ L E+ ++ + +LK + T Y +E DP L +T + D V P Sbjct: 298 IIVYLVEQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHLLYNTHYMLTDDLHVPVVEP 357 Query: 377 -ERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYNKYPGFKEAAAKGL 435 + +++R CE++ RAA LA GIA I ++ + DGS+Y +P F E + Sbjct: 358 IDNRIVRYACEMVVKRAAYLAGAGIACILRRINRSEVTVGVDGSLYKFHPKFCERMTDMV 417 Query: 436 RDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKR 473 + + +EDGSG GAA IAA ++ Sbjct: 418 DKL-----KPKNTRFCLRLSEDGSGKGAAAIAASCTRQ 450 >5ZQT-A nrPDB Length = 473 Score = 504 bits (1297), Expect = e-143, Method: Composition-based stats. Identities = 163/460 (35%), Positives = 238/460 (51%), Gaps = 29/460 (6%) Query: 27 IHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK-GGNIPMIPGWVMEFPTGKESGNYLAI 85 I ++E F+ + LR + ++E+ +GL + M+ +V PTG E G + A+ Sbjct: 16 IEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKMLISYVDNLPTGDEHGLFYAL 75 Query: 86 DLGGTNLRVVLVKLSGNHTFDTTQSKYKL---PHDMRTTKHQEELWSFIADSLKDFMV-- 140 DLGGTN RV+ V+L G +Q ++ PH M T EL+ FIA L+ F+ Sbjct: 76 DLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSM--ELFDFIAAELESFVKTE 133 Query: 141 -EQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR 199 E L LGFTFS+P Q I+ G L +WTKGF I G DVV L + ++ Sbjct: 134 GEDFHLPEGRQRELGFTFSFPVHQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQ 193 Query: 200 ELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIP 259 L +++ AL+NDTVGTL Y D + VI GTG N A+ + + I K G L P Sbjct: 194 GLDMKVTALVNDTVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLL----P 249 Query: 260 SNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLL 319 + M IN E+G+F +E L PR+ YD A+D +S PG+Q +EKM SG YLGE++R +LL Sbjct: 250 RSGNMVINMEWGNFKSERL--PRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRILL 307 Query: 320 ELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVK-TTLPER 378 +L + D +KL+Q +I+ T + + D +L+ + GV T+L R Sbjct: 308 KLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKDILGVADTSLEAR 367 Query: 379 KLIRRLCELIGTRAARLAVCGIAAICQKRGY----------KTGHIAADGSVYNKYPGFK 428 + +C+L+ R ARLA GI I +K G + IA DG +Y Y F+ Sbjct: 368 YITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDGSQKQRTVIALDGGLYEHYKKFR 427 Query: 429 EAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAA 468 L D+ G + + + + A DGSG GAA++AA Sbjct: 428 TCLEATLADLLG---EEAASSVVVKLANDGSGIGAALLAA 464 >4QS9-A nrPDB Length = 474 Score = 492 bits (1267), Expect = e-139, Method: Composition-based stats. Identities = 164/463 (35%), Positives = 240/463 (51%), Gaps = 27/463 (5%) Query: 22 ELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKGGN-IPMIPGWVMEFPTGKESG 80 ++ + E+ LR+V E++ GL GG+ + M+ +V P+G E G Sbjct: 14 RVLAILKAFEEDCATPISKLRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKG 73 Query: 81 NYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKL---PHDMRTTKHQEELWSFIADSLKD 137 + A+DLGGTN RV+ V L G Q ++ PH M T +EL++FIA++L Sbjct: 74 LFYALDLGGTNFRVMRVLLGGKQERVVKQEFEEVSIPPHLM--TGGSDELFNFIAEALAK 131 Query: 138 FM---VEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQN 194 F+ E L LGFTF++P Q ++ G L +WTKGF I G DVV L Sbjct: 132 FVATECEDFHLPEGRQRELGFTFAFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGALNK 191 Query: 195 EISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKL 254 + + L + I AL+NDTVGTL Y +P+ VI GTG N A+ + + I K G L Sbjct: 192 ALERVGLDMRIAALVNDTVGTLAGGRYYNPDVVAAVILGTGTNAAYVERATAIPKWHGLL 251 Query: 255 ADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELL 314 P + M IN E+G+F + HL P T++D +D +S PG+Q EK+ SG YLGE+L Sbjct: 252 ----PKSGEMVINMEWGNFRSSHL--PLTEFDHTLDFESLNPGEQILEKIISGMYLGEIL 305 Query: 315 RLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTT 374 R VLL++ E D SKL+ P+I+ T + + + +D +L+ + V TT Sbjct: 306 RRVLLKMAEDAAFFGDTVPSKLRIPFIIRTPHMSAMHNDTSPDLKIVGSKIKDILEVPTT 365 Query: 375 -LPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGH--------IAADGSVYNKYP 425 L RK++ LC +I TR ARL+ GI I +K G T IA DG ++ Y Sbjct: 366 SLKMRKVVISLCNIIATRGARLSAAGIYGILKKLGRDTTKDEEVQKSVIAMDGGLFEHYT 425 Query: 426 GFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAA 468 F E L+++ G D + + + + DGSG GAA++AA Sbjct: 426 QFSECMESSLKELLG---DEASGSVEVTHSNDGSGIGAALLAA 465 >2YHX-A nrPDB Length = 457 Score = 352 bits (903), Expect = 2e-97, Method: Composition-based stats. Identities = 132/410 (32%), Positives = 192/410 (46%), Gaps = 10/410 (2%) Query: 63 IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTK 122 IPM+PGWV++ +G ++G++LAI +GG +L V+L+ L+G S+ L M TT Sbjct: 44 IPMVPGWVLKQVSGAQAGSFLAIVMGGGDLEVILISLAGRQESSIXASR-SLAAAMSTTA 102 Query: 123 HQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPN 182 +LW A S E + ++PLGFTF ++ + +G + F + Sbjct: 103 IPSDLWGNXAXS-NAAFSSXEFSSXAGSVPLGFTFXEAGAKEXVIKGQITXQAXAFSLAX 161 Query: 183 VEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYD 242 + ++ + N VA I D+ G L YTD KMG+IFG+GVN A++ Sbjct: 162 LX--KLISAMXNAXFPAGDXXXSVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAYWC 219 Query: 243 VVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFE 302 + I M I C+ SF LP+ Y ++ SP + F Sbjct: 220 DSTXIGDA--ADGGXXGGAGXMXICCDQSSFRKAFPSLPQIXYLXTLNXXSP-XAXKTFX 276 Query: 303 KMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTD 362 K + G+ LR VL+ G + +TSYPA+I+ P +L Sbjct: 277 KNSXAKNXGQSLRDVLMXFKXXG-QXHXXXAXSFXAANVENTSYPAKIQKLPHFDLRXXX 335 Query: 363 DIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYN 422 D+F D G+ + ++RR LI A RL VC I AICQK+GY +GHIAA GS Sbjct: 336 DLFXGDQGIAXKTXMKXVVRRXLFLIAAYAFRLVVCXIXAICQKKGYSSGHIAAXGSX-R 394 Query: 423 KYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSE 471 Y GF +A +IYGW A PI I PA DG GA + VI +++ Sbjct: 395 SYSGFSXNSATXNXNIYGWPQSAXXSKPIXITPAIDGXGAASXVIXSIAS 444 >1HKG-A nrPDB Length = 457 Score = 339 bits (869), Expect = 2e-93, Method: Composition-based stats. Identities = 132/416 (31%), Positives = 192/416 (46%), Gaps = 10/416 (2%) Query: 63 IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTK 122 IPM+PGWV++ G ++G++LAI +GG +L V+L+ L+G S+ L M TT Sbjct: 44 IPMVPGWVLKQVXGSQAGSFLAIVMGGGDLEVILIXLAGYQESSIXASR-SLAASMXTTA 102 Query: 123 HQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPN 182 +LW A S E + ++PLGFTF ++ + +G + F + Sbjct: 103 IPSDLWGNXAXS-NAAFSSXEFSSXAGSVPLGFTFXEAGAKEXVIKGQITXQAXAFSLAX 161 Query: 183 VEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYD 242 + ++ + N VA I D+ G L YTD KMG+IFG+GVN A++ Sbjct: 162 LX--KLISAMXNAXFPAGDXXXXVADIXDSHGILXXVNYTDAXIKMGIIFGSGVNAAYWC 219 Query: 243 VVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFE 302 + I A M + C SF LP+ Y ++ SP + FE Sbjct: 220 DSTXIADA--ADAGXXGGAGXMXVCCXQDSFRKAFPSLPQIXYXXTLNXXSP-XAXKTFE 276 Query: 303 KMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTD 362 K + G+ LR VL+ G + ++SYPA+I+ P +L Sbjct: 277 KNSXAKNXGQSLRDVLMXYKXXG-QXHXXXAXDFXAANVENSSYPAKIQKLPHFDLRXXX 335 Query: 363 DIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYN 422 D+F D G+ + ++RR LI A RL VC I AICQK+GY +GHIAA GS Sbjct: 336 DLFXGDQGIAXKTXMKXVVRRXLFLIAAYAFRLVVCXIXAICQKKGYSSGHIAAXGSX-R 394 Query: 423 KYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEG 477 Y GF +A +IYGW A PI I PA DG GA VI +++ + Sbjct: 395 DYSGFSXNSATXNXNIYGWPQSAXXSKPIXITPAIDGEGAAXXVIXSIASSQXXXA 450 >2FEZ-A nrPDB Length = 388 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 23/74 (31%), Gaps = 3/74 (4%) Query: 346 YPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCE---LIGTRAARLAVCGIAA 402 Y + + D D G+ R L R+ L ++A+ G Sbjct: 216 YLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVT 275 Query: 403 ICQKRGYKTGHIAA 416 + +R +G A Sbjct: 276 VLDQRTMASGQQAV 289 >5CY4-A nrPDB Length = 196 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 22/45 (48%) Query: 21 KELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKGGNIPM 65 LM E+ Q +D T++++ K + E+ GL K ++ M Sbjct: 126 HRLMPELEQYFHYRNLDVSTVKELSKRWRPEIMSGLKKNASHLAM 170 >4BAX-A nrPDB Length = 344 Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 9/90 (10%) Query: 115 PHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGF-TFSYPASQNKINEGILQR 173 PH T EL A F +EQE K T PLGF +PA+Q G+ Sbjct: 88 PHPSNTRAALAELSERFAAQEPVFGIEQEYTFFKGTRPLGFPEGGFPAAQGGYYCGV--- 144 Query: 174 WTKGFDIPNVEGHDVVPLLQNEISKRELPI 203 + G DVV K L I Sbjct: 145 -----GSDEIFGRDVVEAHLENCLKAGLGI 169 >6EMK-G nrPDB Length = 426 Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 50/130 (38%), Gaps = 20/130 (15%) Query: 237 NGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRP 296 N + + I D ++P+ + EYGS + + + +V++D+ Sbjct: 119 NDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSI--SCMKMLLNEGEVSLDDNVRDK 176 Query: 297 GQ-------QAFEKMTSGYYLGELLRLVLLELNEKGLMLK-DQDLSKLKQPYIMDTSYPA 348 G Q FE +G + VL E+ +KG L + S + P I++ A Sbjct: 177 GNWKPIDVAQTFE-------VGNIYSKVLKEVKKKGPPLGAGKKPSSFRTP-ILNAK--A 226 Query: 349 RIEDDPFENL 358 ED P L Sbjct: 227 TFEDGPSPVL 236 >6CE1-A nrPDB Length = 686 Score = 28.8 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 24/71 (33%) Query: 354 PFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGH 413 ++LED + + G + KL+ RA +CG +C+ + G Sbjct: 195 CLQDLEDMSVMVLRTQGPAALFDDHKLVLHTSSYDAKRAQVFHICGPEDVCEAYRHVLGQ 254 Query: 414 IAADGSVYNKY 424 V + Sbjct: 255 DKVSYEVPRLH 265 >1WZC-A nrPDB Length = 249 Score = 28.5 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 10/135 (7%) Query: 14 GSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKG---LTKKGGNIPMIPGWV 70 G D K +++E+ + +S R +++ EL +++ G I + G+ Sbjct: 16 GYEPDPAKPIIEELKDMGFEIIFNSSKTRAEQEYYRKELEVETPFISENGSAIFIPKGYF 75 Query: 71 MEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSF 130 GKE GNY+ I+LG +RV + ++ Y L + +TK + E ++ Sbjct: 76 PFDVKGKEVGNYIVIELG---IRVEKI----REELKKLENIYGLKYYGNSTKEEIEKFTG 128 Query: 131 IADSLKDFMVEQELL 145 + L +E+E Sbjct: 129 MPPELVPLAMEREYS 143 >4W8B-A nrPDB Length = 386 Score = 28.5 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 52/147 (35%), Gaps = 13/147 (8%) Query: 105 FDTTQSKYKLPHDMRTTKHQE---ELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPA 161 F + S Y+ + T +LW+ IA+ KD+ + FS Sbjct: 108 FSKSSSSYQAVDEATITSKITRLKDLWTQIANEFKDYDEHLLFAGLNEPFQEYSLFS--G 165 Query: 162 SQNKINEGILQRWTKGF--DIPNVEGHDVVPLLQNEISKRELPIEIVALIND----TVG- 214 ++ IL R+ + F + G++ L + + + + D T G Sbjct: 166 HHEELTP-ILCRYNQAFVEAVRATGGNNAQRTLVVQGPSTNINSSVNYMTADKLPETAGR 224 Query: 215 TLIASYYTDPETKMGVIFGTGVNGAFY 241 ++ +Y DP G +G N ++ Sbjct: 225 LMVEVHYYDPGQFCGTFDASGDNAFYF 251 >6MSK-b nrPDB Length = 377 Score = 28.1 bits (61), Expect = 8.6, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 32/75 (42%), Gaps = 3/75 (4%) Query: 319 LELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDF-GVKTTLPE 377 ++++ +G + + + MDTS PA+ EDD ++ + Q + P Sbjct: 291 MQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDD--YDVMQDPEFLQSVLENLPGVDPN 348 Query: 378 RKLIRRLCELIGTRA 392 + IR + ++A Sbjct: 349 NEAIRNAMGSLASQA 363 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.319 0.137 0.364 Lambda K H 0.267 0.0420 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,907,451 Number of Sequences: 36641 Number of extensions: 776191 Number of successful extensions: 2588 Number of sequences better than 10.0: 26 Number of HSP's better than 10.0 without gapping: 36 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2333 Number of HSP's gapped (non-prelim): 69 length of query: 485 length of database: 10,336,785 effective HSP length: 101 effective length of query: 384 effective length of database: 6,636,044 effective search space: 2548240896 effective search space used: 2548240896 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 61 (28.1 bits)