BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04789 (250 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1KV5-A nrPDB 509 e-145 1TRI-A nrPDB 431 e-121 2Y70-A nrPDB 423 e-119 3Q37-A nrPDB 412 e-116 1CI1-A nrPDB 397 e-111 2VXN-A nrPDB 375 e-105 2V5B-A nrPDB 365 e-102 5CG7-A nrPDB 365 e-101 6NEE-A nrPDB 269 9e-73 4POC-A nrPDB 258 1e-69 6CG9-A nrPDB 256 7e-69 2I9E-A nrPDB 255 1e-68 4OBT-A nrPDB 255 1e-68 1SW7-A nrPDB 253 6e-68 4MKN-A nrPDB 251 2e-67 1I45-A nrPDB 246 8e-66 3TH6-A nrPDB 244 2e-65 4OHQ-A nrPDB 244 3e-65 5ZGA-A nrPDB 244 3e-65 5UPR-A nrPDB 233 7e-62 5EYW-A nrPDB 227 3e-60 3KRS-A nrPDB 225 2e-59 1MO0-A nrPDB 219 1e-57 3PF3-A nrPDB 214 3e-56 1TMH-A nrPDB 212 1e-55 1LZO-A nrPDB 210 5e-55 1M6J-A nrPDB 202 8e-53 1B9B-A nrPDB 197 4e-51 5VWN-A nrPDB 193 7e-50 1BTM-A nrPDB 178 2e-45 4Y8F-A nrPDB 178 2e-45 4G1K-A nrPDB 177 5e-45 5UJW-A nrPDB 176 9e-45 4Y96-A nrPDB 172 2e-43 4X22-A nrPDB 169 7e-43 1AW2-A nrPDB 166 9e-42 3UWW-A nrPDB 166 1e-41 1YYA-A nrPDB 165 2e-41 5IBX-C nrPDB 162 9e-41 4NVT-A nrPDB 158 2e-39 4Y9A-A nrPDB 157 5e-39 3KXQ-A nrPDB 152 1e-37 6BVE-A nrPDB 150 6e-37 3TA6-A nrPDB 143 7e-35 4Y90-A nrPDB 138 2e-33 2JGQ-A nrPDB 111 4e-25 3S6D-A nrPDB 100 8e-22 5CSS-A nrPDB 39 0.001 1W0M-A nrPDB 36 0.015 2H6R-A nrPDB 34 0.064 1HG3-A nrPDB 34 0.072 1GM5-A nrPDB 29 1.6 5ZBK-A nrPDB 28 4.6 >1KV5-A nrPDB Length = 250 Score = 509 bits (1310), Expect = e-145, Method: Compositional matrix adjust. Identities = 249/250 (99%), Positives = 249/250 (99%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF Sbjct: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 Query: 61 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG Sbjct: 61 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP Sbjct: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QQAQEAHALI SWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP Sbjct: 181 QQAQEAHALISSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 Query: 241 EFVDIIKATQ 250 EFVDIIKATQ Sbjct: 241 EFVDIIKATQ 250 >1TRI-A nrPDB Length = 243 Score = 431 bits (1109), Expect = e-121, Method: Compositional matrix adjust. Identities = 236/250 (94%), Positives = 237/250 (94%), Gaps = 7/250 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF Sbjct: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 Query: 61 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 VIAAQNA +L LKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG Sbjct: 61 VIAAQNA-------GNADALASLKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 113 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP Sbjct: 114 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 173 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP Sbjct: 174 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 233 Query: 241 EFVDIIKATQ 250 EFVDIIKATQ Sbjct: 234 EFVDIIKATQ 243 >2Y70-A nrPDB Length = 245 Score = 423 bits (1087), Expect = e-119, Method: Compositional matrix adjust. Identities = 222/252 (88%), Positives = 230/252 (91%), Gaps = 9/252 (3%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVH--LAMTKERLSHP 58 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVA ++ AMTKERLSHP Sbjct: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVAPSWYMGAQAMTKERLSHP 60 Query: 59 KFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 KFVIAAQNA +L LKDFG++WIVL HSERRAYYGETNEIVADKVAAAVA Sbjct: 61 KFVIAAQNA-------GNADALASLKDFGISWIVLDHSERRAYYGETNEIVADKVAAAVA 113 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 SGFMVIACIGETLQER SGRTAVVVLTQI AIAKKLKKADWAKVVIAYEPVWAIGTGKVA Sbjct: 114 SGFMVIACIGETLQERSSGRTAVVVLTQITAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 173 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 TPQQAQEAHALIRSWVSSK+GADVAGELRILYGGSVNG+NARTLYQQRDVNGFLVGGASL Sbjct: 174 TPQQAQEAHALIRSWVSSKVGADVAGELRILYGGSVNGRNARTLYQQRDVNGFLVGGASL 233 Query: 239 KPEFVDIIKATQ 250 KPEFVDIIKAT+ Sbjct: 234 KPEFVDIIKATE 245 >3Q37-A nrPDB Length = 251 Score = 412 bits (1060), Expect = e-116, Method: Compositional matrix adjust. Identities = 202/249 (81%), Positives = 227/249 (91%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVA TF+H+ MTK RL++PKF Sbjct: 3 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVAPTFLHIPMTKARLTNPKFQ 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 IAAQNAI +SGAFTGEVSL ILKD+G++W+VLGHSERRAYYGETNEIVADKVAAAVASGF Sbjct: 63 IAAQNAITRSGAFTGEVSLQILKDYGISWVVLGHSERRAYYGETNEIVADKVAAAVASGF 122 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI C+GET +ERE+GRTA VVLTQ+AA+A+KL K W++VVIAYEPVWAIGTGKVATPQ Sbjct: 123 HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQ 182 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WV SK+G D+A +LRILYGGSV KNARTLYQ RD+NGFLVGGASLKPE Sbjct: 183 QAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE 242 Query: 242 FVDIIKATQ 250 FV+II+AT+ Sbjct: 243 FVEIIEATK 251 >1CI1-A nrPDB Length = 251 Score = 397 bits (1021), Expect = e-111, Method: Compositional matrix adjust. Identities = 184/249 (73%), Positives = 216/249 (86%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 SKPQPIAAANWKCNGS+ L LI+ N+ + +HDVQCVVA TF+H+ MTK RL++PKF Sbjct: 3 SKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPKFQ 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 IAAQNAI +SGAFTGEVSL ILKD+G++W+VLGHSERR YYGETNEIVA+KVA A A+GF Sbjct: 63 IAAQNAITRSGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGF 122 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI C+GET +ERE+GRTA VVLTQ+AA+A+KL K W++VVIAYEPVWAIGTGKVATPQ Sbjct: 123 HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQ 182 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WV SK+G D+A +LRILYGGSV KNARTLYQ RD+NGFLVGGASLKPE Sbjct: 183 QAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE 242 Query: 242 FVDIIKATQ 250 FV+II+AT+ Sbjct: 243 FVEIIEATK 251 >2VXN-A nrPDB Length = 251 Score = 375 bits (964), Expect = e-105, Method: Compositional matrix adjust. Identities = 175/249 (70%), Positives = 209/249 (83%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 +KPQPIAAANWKCNG+ S+ +L+ +FN +I+HDVQCVVA TFVH+ + + +L +PK+V Sbjct: 3 AKPQPIAAANWKCNGTTASIEKLVQVFNEHTISHDVQCVVAPTFVHIPLVQAKLRNPKYV 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 I+AQNAIAKSGAFTGEVS+PILKD GV+W++LGHSERR YYGET+EIVA KV+ A GF Sbjct: 63 ISAQNAIAKSGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGF 122 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 MVIACIGETLQ+RE+ +TA VVL+Q +AIA KL K W +VV+AYEPVWAIGTGKVATP+ Sbjct: 123 MVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKVATPE 182 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WVS IG DVA +LRILYGGSVN NA TLY + D+NGFLVGGASLKPE Sbjct: 183 QAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE 242 Query: 242 FVDIIKATQ 250 F DII AT+ Sbjct: 243 FRDIIDATR 251 >2V5B-A nrPDB Length = 244 Score = 365 bits (938), Expect = e-102, Method: Compositional matrix adjust. Identities = 173/249 (69%), Positives = 205/249 (82%), Gaps = 7/249 (2%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 SKPQPIAAANWKCNGS+ L LI+ N+ + +HDVQCVVA TF+H+ MTK RL++PKF Sbjct: 3 SKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPKFQ 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 IAAQNA +L LKD+G++W+VLGHSERR YYGETNEIVA+KVA A A+GF Sbjct: 63 IAAQNA-------GNADALASLKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGF 115 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI C+GET +ERE+GRTA VVLTQ+AA+A+KL K W++VVIAYEPVWAIGTGKVATPQ Sbjct: 116 HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQ 175 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WV SK+G D+A +LRILYGGSV KNARTLYQ RD+NGFLVGGASLKPE Sbjct: 176 QAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE 235 Query: 242 FVDIIKATQ 250 FV+II+AT+ Sbjct: 236 FVEIIEATK 244 >5CG7-A nrPDB Length = 271 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 169/249 (67%), Positives = 206/249 (82%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 +KPQPI AANWKCNG+ S+ +L+ + N I+HDVQCVVA +FVH+ M + +L +PK+ Sbjct: 23 AKPQPIVAANWKCNGTTASIEKLVQVLNEHQIDHDVQCVVAPSFVHIPMVQAKLCNPKYA 82 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 ++A+NAIAKSGAFTGEVS+PILKD GV+W++LGHSERR YYGET+ +VA KVA A GF Sbjct: 83 VSAENAIAKSGAFTGEVSMPILKDLGVSWVILGHSERRTYYGETDGVVAQKVADAYNQGF 142 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 MVIACIGETLQ+RE+ +TA VVL+Q AAIA KL K W+++V+AYEPVWAIGTGKVATP+ Sbjct: 143 MVIACIGETLQQREANQTAKVVLSQTAAIAAKLPKEAWSQIVLAYEPVWAIGTGKVATPE 202 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE HAL+R WVS KIG VA +LRILYGGSV NA+TLY + D+NGFLVGGASLKPE Sbjct: 203 QAQEVHALLRQWVSEKIGNGVATKLRILYGGSVTAGNAKTLYMKPDINGFLVGGASLKPE 262 Query: 242 FVDIIKATQ 250 F DII AT+ Sbjct: 263 FRDIIDATR 271 >6NEE-A nrPDB Length = 252 Score = 269 bits (687), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 134/244 (54%), Positives = 176/244 (72%), Gaps = 6/244 (2%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV-IAAQNAIA 69 NWK NG+ +S+ L++ NS ++ + + VVA ++L + +L PK + +AAQN Sbjct: 11 NWKMNGTLESIKALVETLNSAQLDPNTEVVVAPPAIYLPFARSKLKKPKEIQVAAQNCYT 70 Query: 70 K-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIG 128 K +GAFTGE+S +LKD GV W++LGHSERR +GE++E++A+KV A+ G VIACIG Sbjct: 71 KPNGAFTGEISAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALDQGLKVIACIG 130 Query: 129 ETLQERESGRTAVVVLTQI-AAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 ETL+ERE+G+T VV QI AIA K+K DW+ VVIAYEPVWAIGTGKVATP+QAQE H Sbjct: 131 ETLEEREAGKTMEVVARQILKAIADKIK--DWSNVVIAYEPVWAIGTGKVATPEQAQEVH 188 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-PEFVDII 246 A +R W+ + +VA RI+YGGSVN N + L +Q D++GFLVGGASLK PEFVDII Sbjct: 189 AALRKWLKENVSPEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLKAPEFVDII 248 Query: 247 KATQ 250 A Q Sbjct: 249 NARQ 252 >4POC-A nrPDB Length = 254 Score = 258 bits (660), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 131/243 (53%), Positives = 162/243 (66%), Gaps = 4/243 (1%) Query: 9 AANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAI 68 NWK NG +QSL ELI N+ + D + V A ++ +++L PK +AAQN Sbjct: 15 GGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCY 73 Query: 69 -AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 +GAFTGE+S ++KD G W+VLGHSERR +GE++E++ KVA A+A G VIACI Sbjct: 74 KVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACI 133 Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 GE L ERE+G T VV Q IA +K DW+KVV+AYEPVWAIGTGK ATPQQAQE H Sbjct: 134 GEKLDEREAGITEKVVFEQTKVIADNVK--DWSKVVLAYEPVWAIGTGKTATPQQAQEVH 191 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIK 247 +R W+ S + VA RI+YGGSV G + L Q DV+GFLVGGASLKPEFVDII Sbjct: 192 EKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIIN 251 Query: 248 ATQ 250 A Q Sbjct: 252 AKQ 254 >6CG9-A nrPDB Length = 256 Score = 256 bits (654), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 130/241 (53%), Positives = 167/241 (69%), Gaps = 6/241 (2%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKFVIAAQNA- 67 NWKCNG+ + +++ N + V+ VV+ +V L + K +L +F +AAQN Sbjct: 13 NWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQ-EFHVAAQNCW 71 Query: 68 IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 + K GAFTGEVS +L + GV W++LGHSERRA GE+NE V DKVA A++ G VIAC+ Sbjct: 72 VKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALSQGLKVIACV 131 Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 GETL++RE+G T VV Q AIA+K+K DW+ VV+AYEPVWAIGTGKVATP QAQE H Sbjct: 132 GETLEQREAGSTMDVVAAQTKAIAEKIK--DWSNVVVAYEPVWAIGTGKVATPAQAQEVH 189 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIK 247 A +R W+ + +VA RI+YGGSV N + L Q DV+GFLVGGASLKPEF+DII Sbjct: 190 ASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKPEFIDIIN 249 Query: 248 A 248 A Sbjct: 250 A 250 >2I9E-A nrPDB Length = 259 Score = 255 bits (652), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 127/246 (51%), Positives = 165/246 (67%), Gaps = 6/246 (2%) Query: 7 IAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV-IAAQ 65 + NWK NG ++ ++E+I S +N D + VV ++L + R P + +AAQ Sbjct: 6 VVGGNWKMNGDKKQINEIIGFLKSGPLNQDTEVVVGVPAIYLELV--RTCVPASIGVAAQ 63 Query: 66 NAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVI 124 N GAFTGE+S ++KD G +W++LGHSERR +GE++E++A+KV A+ SG VI Sbjct: 64 NCYKVPKGAFTGEISPAMIKDVGADWVILGHSERRQIFGESDELIAEKVCHALESGLKVI 123 Query: 125 ACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQ 184 ACIGETL+ERE+G+T VV Q AIA K+ DW+ VVIAYEPVWAIGTGK ATPQQAQ Sbjct: 124 ACIGETLEEREAGKTEEVVFRQTKAIAAKVN--DWSNVVIAYEPVWAIGTGKTATPQQAQ 181 Query: 185 EAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVD 244 + H +R W+ I A V +RI YGGSV N + L Q D++GFLVGGASLKPEFVD Sbjct: 182 DVHKALRQWICENIDAKVGNSIRIQYGGSVTAANCKELASQPDIDGFLVGGASLKPEFVD 241 Query: 245 IIKATQ 250 II A Q Sbjct: 242 IINARQ 247 >4OBT-A nrPDB Length = 257 Score = 255 bits (652), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 129/243 (53%), Positives = 168/243 (69%), Gaps = 6/243 (2%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKFVIAAQNA- 67 NWKCNG+ + + ++++ N + V+ VV+ +V L + K L F +AAQN Sbjct: 13 NWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFVAAQNCW 71 Query: 68 IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 + K GAFTGEVS +L + + W++LGHSERRA E++E V DKVA A+A G VIAC+ Sbjct: 72 VKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACV 131 Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 GETL+ERE+G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+P QAQE H Sbjct: 132 GETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTGKVASPAQAQEVH 189 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIK 247 +R W++ + ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLKPEF+DIIK Sbjct: 190 DELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDIIK 249 Query: 248 ATQ 250 A + Sbjct: 250 AAE 252 >1SW7-A nrPDB Length = 248 Score = 253 bits (645), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 128/251 (50%), Positives = 164/251 (65%), Gaps = 4/251 (1%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M+ + NWK NG ++SL ELI N ++ D + V + ++L +++L K Sbjct: 1 MAPRKFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLD-AKI 59 Query: 61 VIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 +AAQN GAFTGE+S ++KD G W++LGHSERR +GE++E++ KVA A+A Sbjct: 60 GVAAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAE 119 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G VIACIGE L ERE+G T VV Q AIA +K DW+KVV+AYEPVWAIGTG +T Sbjct: 120 GLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVK--DWSKVVLAYEPVWAIGTGNSST 177 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 PQQAQE H +R W+ S + VA RI+YGGSV G N + L Q DV+GFLVGGASLK Sbjct: 178 PQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLK 237 Query: 240 PEFVDIIKATQ 250 PEFVDII A Sbjct: 238 PEFVDIINAKH 248 >4MKN-A nrPDB Length = 270 Score = 251 bits (642), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 127/240 (52%), Positives = 172/240 (71%), Gaps = 4/240 (1%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNA-IA 69 NWKCNGS ++++L+D N+ +I V VVA F+++ + L K+ ++AQNA I Sbjct: 26 NWKCNGSVANVAKLVDELNAGTIPRGVDVVVAPPFIYIDYVMQHLDRDKYQLSAQNAWIG 85 Query: 70 KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGE 129 +GAFTGEVS L DFGV W++LGHSERR+ +GE+NE+VA K + A+A+G VIACIGE Sbjct: 86 GNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAGLGVIACIGE 145 Query: 130 TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHAL 189 TL++R SG V+ Q+ A+ ++K DW KVV+AYEPVWAIGTG VA+P+QAQE HA Sbjct: 146 TLEQRNSGSVFKVLDAQMDALVDEVK--DWTKVVLAYEPVWAIGTGVVASPEQAQEVHAY 203 Query: 190 IRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-PEFVDIIKA 248 +R + + K+GA VA +LRI+YGGSV+ N + L +Q D++GFLVGGASLK FV I A Sbjct: 204 LRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGAAFVTICNA 263 >1I45-A nrPDB Length = 248 Score = 246 bits (627), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 121/241 (50%), Positives = 168/241 (69%), Gaps = 3/241 (1%) Query: 9 AANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAI 68 N+K NGS+QS+ E+++ N+ SI +V+ V+ +L + + P+ + AQNA Sbjct: 8 GGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAY 67 Query: 69 AK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 K SGAFTGE S+ +KD G +++LGHSERR+Y+ E ++ +ADK A+ G VI CI Sbjct: 68 LKASGAFTGENSVDQIKDVGAKYVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCI 127 Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 GETL+E+++G+T VV Q+ A+ +++K D+ VV+AYEPVWAIGTG ATP+ AQ+ H Sbjct: 128 GETLEEKKAGKTLDVVERQLNAVLEEVK--DFTNVVVAYEPVWAIGTGLAATPEDAQDIH 185 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIK 247 A IR +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPEFVDII Sbjct: 186 ASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIIN 245 Query: 248 A 248 + Sbjct: 246 S 246 >3TH6-A nrPDB Length = 249 Score = 244 bits (623), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 121/243 (49%), Positives = 166/243 (68%), Gaps = 4/243 (1%) Query: 9 AANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAI 68 NWK +GS+ S+ ++ + S++ +V+ +VA +L + L P +AAQN Sbjct: 9 GGNWKMHGSKNSIRDICNTLKGASLDPNVEVIVACPAPYLDYCRSLLP-PSVALAAQNCY 67 Query: 69 -AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 + GAFTGE+S ++KD G W++LGHSERR + E + ++ +K+ A+ SG VIACI Sbjct: 68 KVEQGAFTGEISPGMIKDCGGQWVILGHSERRHVFKEDDVLIGEKIKHALESGLNVIACI 127 Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 GE L++RE+GRT V QI IA +K DW+KVVIAYEPVWAIGTGK ATP QAQE H Sbjct: 128 GELLEDREAGRTEEVCFRQIKHIASNVK--DWSKVVIAYEPVWAIGTGKTATPDQAQEVH 185 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIK 247 + +R+W+S+ + ADVA ++RI YGGSVN N + L ++ D++GFLVGGASLKPEFV II Sbjct: 186 SKVRNWLSTNVSADVASKVRIQYGGSVNAGNCKELGRKPDIDGFLVGGASLKPEFVQIIN 245 Query: 248 ATQ 250 A Q Sbjct: 246 AMQ 248 >4OHQ-A nrPDB Length = 256 Score = 244 bits (622), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 119/242 (49%), Positives = 163/242 (67%), Gaps = 5/242 (2%) Query: 9 AANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNA- 67 NWKCNG++ S+++LI NS ++ DV VV+ FV++ K L+ + I+ QN+ Sbjct: 10 GGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTD-RIDISGQNSW 68 Query: 68 IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 + K GAFTGE+S+ LKD G W++LGHSERR GE +E + K A A++ G VIACI Sbjct: 69 VGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACI 128 Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 GE L+ERE+G+T V Q+ A A + W +V+AYEPVWAIGTGKVA+PQQAQE H Sbjct: 129 GEKLEEREAGKTFDVCFAQLKAFADAV--PSWDNIVVAYEPVWAIGTGKVASPQQAQEVH 186 Query: 188 ALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-PEFVDII 246 +R W+ + +VA + RI+YGGSVNG N+ L ++ D++GFLVGGASLK PEF I+ Sbjct: 187 VAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEFATIV 246 Query: 247 KA 248 + Sbjct: 247 NS 248 >5ZGA-A nrPDB Length = 269 Score = 244 bits (622), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 122/240 (50%), Positives = 164/240 (68%), Gaps = 4/240 (1%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAI-A 69 NWK NGS++ +LI++ I+ + + +VA ++L +E+L +F +AAQN Sbjct: 32 NWKMNGSKKENDKLIEMLTHAKIDPNTEVLVAPPALYLPSVREKLDK-RFHVAAQNCYKV 90 Query: 70 KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGE 129 SGAFTGEVS +LKD G +W++LGHSERR ET+++V +K A A+++G VIACIGE Sbjct: 91 PSGAFTGEVSPAMLKDVGCDWVILGHSERRHILLETDQLVGEKTAHAISAGVNVIACIGE 150 Query: 130 TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHAL 189 L+ERE+G+T V Q+ AI K L + W +VIAYEPVWAIGTGK AT QQAQE H Sbjct: 151 KLEEREAGKTEEVCFRQMEAIRKNL--SMWNHIVIAYEPVWAIGTGKTATEQQAQEVHLA 208 Query: 190 IRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKAT 249 +R W+ K+ VA +RI+YGGSV N RTL +Q DV+GFLVGGASLKP+F++I A Sbjct: 209 VRRWMEEKVSPAVAKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASLKPDFIEICNAN 268 >5UPR-A nrPDB Length = 265 Score = 233 bits (594), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 119/248 (47%), Positives = 167/248 (67%), Gaps = 8/248 (3%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHD-VQCVVASTFVHLAMTKERLSHPKFVIAAQNAIA 69 NWKCNG+ EL+D+ NS ++ + V VVA + ++ ++ L P+ +AAQ++ Sbjct: 15 NWKCNGTTAKTQELVDMLNSAPVSFEQVDVVVAPPSLFISQVQDSLRQPRVQVAAQDSST 74 Query: 70 KS--GAFTGEVSLPILKDFGVNWIVLGHSERRAYYG----ETNEIVADKVAAAVASGFMV 123 + GAFTGE+S ++K+ + W+VLGHSERRA +G E+N++VA KV AA+ G V Sbjct: 75 QQAYGAFTGELSPKMIKEKNIPWVVLGHSERRAGFGGQPGESNQVVAKKVRAALNEGLSV 134 Query: 124 IACIGETLQERESGRTAVVVLTQIAAIAKKLKKAD-WAKVVIAYEPVWAIGTGKVATPQQ 182 I CIGETL+ERESG+T V+ Q+ A+ + + +AD W +VIAYEPVWAIGTGK AT Sbjct: 135 ILCIGETLEERESGQTQKVLSEQLEAVRQAVPEADAWKSIVIAYEPVWAIGTGKTATAAL 194 Query: 183 AQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEF 242 AQE H IR+W++ + VA R++YGGSV G NA+ L++ DV+GFLVGGASL +F Sbjct: 195 AQETHRDIRNWLAQAVSPKVAEATRVIYGGSVKGSNAKELFEGEDVDGFLVGGASLTGDF 254 Query: 243 VDIIKATQ 250 V II A + Sbjct: 255 VSIIDAAK 262 >5EYW-A nrPDB Length = 249 Score = 227 bits (579), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 113/251 (45%), Positives = 166/251 (66%), Gaps = 7/251 (2%) Query: 1 MSKPQPI-AAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK 59 M+ P+ NWK NG + ++ +I + ++ + + VV +L T+E + Sbjct: 1 MASPRKFFVGGNWKMNGDKAAIDGIISFMKTGPLSPNTEVVVGCPQCYLMYTREHMPA-N 59 Query: 60 FVIAAQNA--IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAV 117 IAAQN +AK GAFTGE+S ++KD G W++LGHSERR +GE ++++++KV A+ Sbjct: 60 IGIAAQNCYKVAK-GAFTGEISPAMVKDCGCEWVILGHSERRNVFGEPDQLISEKVGHAL 118 Query: 118 ASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKV 177 +G VI CIGE L++RE RT VV Q+ A+ + +DW++VV+AYEPVWAIGTGK Sbjct: 119 EAGLKVIPCIGEKLEDREGNRTQEVVFAQMKALLPNI--SDWSRVVLAYEPVWAIGTGKT 176 Query: 178 ATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGAS 237 A+P+QAQE HA +R W+ + A+VA RI+YGGSV+ N + L ++ D++GFLVGGA+ Sbjct: 177 ASPEQAQEVHADLRQWLRDNVNAEVAESTRIIYGGSVSAGNCQELAKKGDIDGFLVGGAA 236 Query: 238 LKPEFVDIIKA 248 LKP+FV II A Sbjct: 237 LKPDFVQIINA 247 >3KRS-A nrPDB Length = 271 Score = 225 bits (573), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 119/247 (48%), Positives = 161/247 (65%), Gaps = 9/247 (3%) Query: 9 AANWKCNGSQQSLSELIDLFNST-SINHDVQCVVASTFVHLAMTKERL--SHPK-FVIAA 64 N+KCNG+++SL LID F S N +V V T +H+++ KE HP F I + Sbjct: 29 GGNFKCNGTKESLKTLIDSFKQVESSNSEV--YVFPTSLHISLVKEFFGNDHPGVFKIGS 86 Query: 65 QN-AIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMV 123 QN + +GAFTGEVS +LKD V+ ++GHSERR YY ET++IV +KV + +G + Sbjct: 87 QNISCTGNGAFTGEVSCEMLKDMDVDCSLVGHSERRQYYSETDQIVNNKVKKGLENGLKI 146 Query: 124 IACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQA 183 + CIGE+L ERE+G+T V+ Q+ K + +D + +VIAYEP+WAIGTG VATP QA Sbjct: 147 VLCIGESLSERETGKTNDVIQKQLTEALKDV--SDLSNLVIAYEPIWAIGTGVVATPGQA 204 Query: 184 QEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFV 243 QEAHA IR +V+ V+ LRI+YGGSV N L + D++GFLVGGASLKP F Sbjct: 205 QEAHAFIREYVTRMYNPQVSSNLRIIYGGSVTPDNCNELIKCADIDGFLVGGASLKPTFA 264 Query: 244 DIIKATQ 250 II++ Q Sbjct: 265 KIIESAQ 271 >1MO0-A nrPDB Length = 275 Score = 219 bits (557), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 113/239 (47%), Positives = 154/239 (64%), Gaps = 4/239 (1%) Query: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAI-A 69 NWK NG S+ ++ N+++ N V VVA +LA K +L ++AAQN Sbjct: 30 NWKMNGDYASVDGIVTFLNASADNSSVDVVVAPPAPYLAYAKSKLK-AGVLVAAQNCYKV 88 Query: 70 KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGE 129 GAFTGE+S ++KD G+ W++LGHSERR +GE++ ++A+K A+ +G V+ CIGE Sbjct: 89 PKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHALEAGIKVVFCIGE 148 Query: 130 TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHAL 189 L+ERE+G T V Q+ AI K W +VIAYEPVWAIGTGK A+ +QAQE H Sbjct: 149 KLEEREAGHTKDVNFRQLQAIVD--KGVSWENIVIAYEPVWAIGTGKTASGEQAQEVHEW 206 Query: 190 IRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKA 248 IR+++ K+ VA RI+YGGSV NA L ++ D++GFLVGGASLKP+FV II A Sbjct: 207 IRAFLKEKVSPAVADATRIIYGGSVTADNAAELGKKPDIDGFLVGGASLKPDFVKIINA 265 >3PF3-A nrPDB Length = 257 Score = 214 bits (545), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 114/256 (44%), Positives = 159/256 (62%), Gaps = 6/256 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M +P N+KCNGS + + + I V V+A + VHL+ + + Sbjct: 1 MPARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIPDSVDVVIAPSAVHLSTAIAANTSKQL 60 Query: 61 VIAAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 IAAQN + +GA+TGE S+ +L+D G+ +++GHSERR GET+E A K A+ Sbjct: 61 RIAAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEK 120 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKL--KKADWAKVVIAYEPVWAIGTGKV 177 G VI C+GETL ER++ RT V + Q+ A+ K+L K W +VVIAYEPVW+IGTG V Sbjct: 121 GMTVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVV 180 Query: 178 ATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGAS 237 ATP+QA+E H +R W + K+ A+ A +RI+YGGS NG N L Q +++GFLVGGAS Sbjct: 181 ATPEQAEEVHVGLRKWFAEKVAAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGAS 240 Query: 238 LKPEF---VDIIKATQ 250 LKPEF +DI+ T+ Sbjct: 241 LKPEFMTMIDILTKTR 256 >1TMH-A nrPDB Length = 254 Score = 212 bits (539), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 114/248 (45%), Positives = 151/248 (60%), Gaps = 3/248 (1%) Query: 5 QPIAAANWKCNGSQQSLSELI-DLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIA 63 P+ NWK NGS+ + EL+ +L + +A +++ M K ++ Sbjct: 3 HPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLG 62 Query: 64 AQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFM 122 AQN + SGAFTGE S +LKD G +I++GHSERR Y+ E++E++A K A G Sbjct: 63 AQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLT 122 Query: 123 VIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQ 182 + CIGET E E+G+T V QI A+ K A + VIAYEPVWAIGTGK ATP Q Sbjct: 123 PVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQ 182 Query: 183 AQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEF 242 AQ H IR + +K+ A++A ++ I YGGSVN NA L+ Q DV+GFLVGGASLKPEF Sbjct: 183 AQAVHKFIRDHI-AKVDANIAEQVIIQYGGSVNASNAAELFAQHDVDGFLVGGASLKPEF 241 Query: 243 VDIIKATQ 250 VDII A + Sbjct: 242 VDIINAAE 249 >1LZO-A nrPDB Length = 248 Score = 210 bits (534), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 107/245 (43%), Positives = 152/245 (62%), Gaps = 7/245 (2%) Query: 7 IAAANWKCNGSQQSLSELIDLFNSTSIN-HDVQCVVASTFVHLAMTKERLSHPKFVIAAQ 65 AANWKCNG+ +S+ L + FN+ + + VV VH T+ +L KF Q Sbjct: 6 FVAANWKCNGTLESIKSLTNSFNNLDFDPSKLDVVVFPVSVHYDHTR-KLLQSKFSTGIQ 64 Query: 66 NAIAK--SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMV 123 N ++K +G++TGEVS I KD + ++++GH ERR Y+ ET+E V +K+ A++ + Sbjct: 65 N-VSKFGNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLKNNLKA 123 Query: 124 IACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQA 183 + C GE+L++RE +T V+ Q+ A + D V++ YEP+WAIGTGK ATP+QA Sbjct: 124 VVCFGESLEQREQNKTIEVITKQVKAFVDLIDNFD--NVILVYEPLWAIGTGKTATPEQA 181 Query: 184 QEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFV 243 Q H IR V G A ++RILYGGSVN +N +L QQ D++GFLVG ASLK FV Sbjct: 182 QLVHKEIRKIVKDTCGEKQANQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASLKESFV 241 Query: 244 DIIKA 248 DIIK+ Sbjct: 242 DIIKS 246 >1M6J-A nrPDB Length = 261 Score = 202 bits (515), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 106/245 (43%), Positives = 151/245 (61%), Gaps = 7/245 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNST---SINHDVQCVVASTFVHLAMTKERLSH 57 M + + NWKCNG+ S+ L ++ + V+ +V F+++ ++ L+ Sbjct: 1 MGAGKFVVGGNWKCNGTLASIETLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQILAG 60 Query: 58 P----KFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKV 113 +++A+NA KSGA+TGEV + +L D V +++LGHSERR + E+NE VA+KV Sbjct: 61 EANGANILVSAENAWTKSGAYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVAEKV 120 Query: 114 AAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIG 173 A+ +G VIACIGET +R + +T VV Q+ AI + K W +++AYEPVWAIG Sbjct: 121 KVAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVWAIG 180 Query: 174 TGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLV 233 TGK ATP QAQE H IR W++ I +VA RI YGGSVN N L ++ D++GFLV Sbjct: 181 TGKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDGFLV 240 Query: 234 GGASL 238 GGASL Sbjct: 241 GGASL 245 >1B9B-A nrPDB Length = 255 Score = 197 bits (501), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 106/241 (43%), Positives = 143/241 (59%), Gaps = 2/241 (0%) Query: 7 IAAANWKCNGSQQSLSELIDLF-NSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQ 65 I A NWK + + + + L N + + VV F L+ E LS + AQ Sbjct: 6 ILAGNWKMHKTISEAKKFVSLLVNELHDVKEFEIVVCPPFTALSEVGEILSGRNIKLGAQ 65 Query: 66 NAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVI 124 N + GAFTGE+S +L++ GV ++++GHSERR + E +E + KV A + G I Sbjct: 66 NVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLEKGMTPI 125 Query: 125 ACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQ 184 C+GETL+ERE G T VV Q+ L K + +VVIAYEPVWAIGTG+VATPQQAQ Sbjct: 126 LCVGETLEEREKGLTFCVVEKQVREGFYGLDKEEAKRVVIAYEPVWAIGTGRVATPQQAQ 185 Query: 185 EAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVD 244 E HA IR +S + AG +RILYGGS+ N L Q+D++G LVGGASLK F++ Sbjct: 186 EVHAFIRKLLSEMYDEETAGSIRILYGGSIKPDNFLGLIVQKDIDGGLVGGASLKESFIE 245 Query: 245 I 245 + Sbjct: 246 L 246 >5VWN-A nrPDB Length = 246 Score = 193 bits (490), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 99/240 (41%), Positives = 146/240 (60%), Gaps = 7/240 (2%) Query: 11 NWKCNGSQ-QSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIA 69 NWK N Q +L+++ N + +V+ VVA+ FV L +++L + ++A+N Sbjct: 9 NWKANPKTVQEAEKLVEMLNGAKVEGNVEVVVAAPFVFLPTLQQKLRK-DWKVSAENVFT 67 Query: 70 KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGE 129 K ++P++K FG+ W +LGHSERR E +E +A K A+ +G +I C GE Sbjct: 68 KPNG-----TVPMIKSFGIEWTILGHSERRDILKEDDEFLAAKAKFALENGMKIIYCCGE 122 Query: 130 TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHAL 189 L ERE+G+ + V QI + + W VVIAYEP+WAIGTGKVA+ Q AQE + Sbjct: 123 HLSEREAGKASEFVSAQIEKMIPAIPAGKWDDVVIAYEPIWAIGTGKVASTQDAQEMCKV 182 Query: 190 IRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKAT 249 IR +++K+GAD+A ++RILYGGSV N L DV+GFLVGGASL+ F++I+ + Sbjct: 183 IRDILAAKVGADIANKVRILYGGSVKPNNCNELAACPDVDGFLVGGASLEAGFINIVNSN 242 >1BTM-A nrPDB Length = 252 Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 104/250 (41%), Positives = 143/250 (57%), Gaps = 9/250 (3%) Query: 5 QPIAAANWKCNGSQQSLSELI----DLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 +PI A NWK + ++L+E + D+ +V VV + F+ L + Sbjct: 2 KPIIAGNWKMH---KTLAEAVQFVEDVKGHVPPADEVISVVCAPFLFLDRLVQAADGTDL 58 Query: 61 VIAAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 I AQ A GA+TGEVS +LKD GV +++LGHSERR + ET+E V KV AA Sbjct: 59 KIGAQTMHFADQGAYTGEVSPVMLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTR 118 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G + I C GE+L+ERE+G+T VV +Q+ L + VIAYEP+WAIGTGK +T Sbjct: 119 GLIPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQAVIAYEPIWAIGTGKSST 178 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 P+ A IRS VS G + A +RI YGGSV N R Q+ ++G LVGGASL+ Sbjct: 179 PEDANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGPLVGGASLE 238 Query: 240 P-EFVDIIKA 248 P F+ +++A Sbjct: 239 PASFLQLVEA 248 >4Y8F-A nrPDB Length = 251 Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 98/234 (41%), Positives = 135/234 (57%), Gaps = 1/234 (0%) Query: 6 PIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQ 65 PI A NWK + + +L++ + + VV TFV L K+ + + AQ Sbjct: 7 PIIAGNWKMHYTIDEAVKLVEELKPLVKDAKCEVVVCPTFVCLDAVKKAVEGTNIKVGAQ 66 Query: 66 NA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVI 124 N + GAFTGE++ +L+ ++++++GHSERR Y+ ET+E KV AA A I Sbjct: 67 NMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHNLTPI 126 Query: 125 ACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQ 184 C GETL++RE+G T V+ QI A + L K KVVIAYEP+WAIGTGK AT QA Sbjct: 127 LCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATSDQAN 186 Query: 185 EAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 E A IR+ V+ G +VA ++RI YGGSV + D++G LVGGASL Sbjct: 187 ETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASL 240 >4G1K-A nrPDB Length = 272 Score = 177 bits (448), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 104/246 (42%), Positives = 155/246 (63%), Gaps = 12/246 (4%) Query: 11 NWKCNG----SQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQN 66 NWK +G +Q L+E+ + +++ +V V F +LA + +L + +Q+ Sbjct: 33 NWKMHGRLSGNQALLTEVAQ--GAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQD 90 Query: 67 AIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIA 125 A + GA+TGEV+ ++ +FG + ++GHSERRAY+GE+NE VA K A+A+G I Sbjct: 91 VSAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPIV 150 Query: 126 CIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQE 185 C+GETL ERE+G T VV Q+ A+ L + A++V+AYEPVWAIGTGK AT +QAQ+ Sbjct: 151 CVGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGKSATAEQAQQ 210 Query: 186 AHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP-EFVD 244 HA +R ++ A AG + +LYGGSV NA L+ Q D++G L+GGASLK +F+ Sbjct: 211 VHAFLR----GRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKSGDFLA 266 Query: 245 IIKATQ 250 I +A + Sbjct: 267 ICRAAK 272 >5UJW-A nrPDB Length = 253 Score = 176 bits (446), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 98/246 (39%), Positives = 148/246 (60%), Gaps = 7/246 (2%) Query: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSH--PKFVI 62 Q + NWK NG+ S+ EL + + +D V + F KE +S K + Sbjct: 2 QKLIMGNWKMNGNSTSIKELCS--GISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGV 59 Query: 63 AAQN-AIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 QN GA+TGE+S +L+D G +++++GHSERR+ + E++E V K+ + + Sbjct: 60 GLQNITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTI 119 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + CIGE+L +R+SG+ V+ TQ++ I + L AKVVIAYEPVWAIGTG VA+ + Sbjct: 120 TPVVCIGESLDDRQSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLE 179 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-P 240 Q QE H IRS + +K+ +A ++I+YGGS+ +NA+ + DV+G L+GGASLK Sbjct: 180 QIQETHQFIRSLL-AKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAA 238 Query: 241 EFVDII 246 EF +II Sbjct: 239 EFNEII 244 >4Y96-A nrPDB Length = 255 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 104/250 (41%), Positives = 134/250 (53%), Gaps = 2/250 (0%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M + A NWK N + L + V V + L E L Sbjct: 4 MPTRKKFVAGNWKMNTTLAEAKALGAAVAKGVTDDRVTVAVFPPYPWLTAVGEVLKGSPV 63 Query: 61 VIAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 + AQ+ + K GAFTGEVS +L + G + ++GHSERR GE+ + KV A+ Sbjct: 64 ALGAQDVSSEKKGAFTGEVSPAMLLETGCKYALIGHSERRHIIGESETFINHKVHTALEE 123 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G V+ C+GETL ERE G V Q+ A L + ++VIAYEPVWAIGTGKVAT Sbjct: 124 GLSVVLCMGETLAERERGLQERVFQRQVYAACAGLTDEQFGRIVIAYEPVWAIGTGKVAT 183 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 P+QAQEAHA +RS + G +A I+YGGSV N L Q DV+G LVGGASLK Sbjct: 184 PEQAQEAHAFVRSKLRLLYGDKIADSTPIVYGGSVTPDNTVGLMSQPDVDGALVGGASLK 243 Query: 240 PE-FVDIIKA 248 + F+ I+KA Sbjct: 244 ADSFLAIVKA 253 >4X22-A nrPDB Length = 250 Score = 169 bits (429), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 103/243 (42%), Positives = 145/243 (59%), Gaps = 11/243 (4%) Query: 5 QPIAAANWKCNGSQQSLSELIDLFNST-----SINHDVQCVVASTFVHLAMTKERLSHPK 59 + I A NWK N SL E + L +S SI+ D +V + +HL + L Sbjct: 3 KTIIAGNWKMN---LSLKEAVFLAHSIREKIPSISKDKVSMVFPSTLHLENVSKILEGSS 59 Query: 60 FVIAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 ++ AQN AFTGE S LK+ GV +++GHSERR + GE+N DK+ + Sbjct: 60 VIVGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLLK 119 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 + F V+ C+GETL ERESG+T V+ +QI K + ++ +++AYEPVWAIGTGKVA Sbjct: 120 NEFTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKVA 179 Query: 179 TPQQAQEAHALIRSWVSSK-IGA-DVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGA 236 TP QAQE H+ IR +S +GA ++ + ILYGGSV N + L +++D++G LVGGA Sbjct: 180 TPSQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGGA 239 Query: 237 SLK 239 S K Sbjct: 240 SQK 242 >1AW2-A nrPDB Length = 256 Score = 166 bits (420), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 96/240 (40%), Positives = 138/240 (57%), Gaps = 9/240 (3%) Query: 5 QPIAAANWKCNGSQQSLSELIDLFNS-----TSINHDVQCVVASTFVHLAMTKERLSHPK 59 P+ NWK NGS++ + +L++ N+ T + DV + FV LA + Sbjct: 3 HPVVMGNWKLNGSKEMVVDLLNGLNAELEGVTGV--DVAVAPPALFVDLAERTLTEAGSA 60 Query: 60 FVIAAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 ++ AQN + SGAFTG++S +LK+FG I++GHSERR Y+ E++E VA K A Sbjct: 61 IILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHAESDEFVAKKFAFLKE 120 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 +G + CIGE+ + E+G T V Q+ A+ +IAYEP+WAIGTGK A Sbjct: 121 NGLTPVLCIGESDAQNEAGETMAVCARQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAA 180 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 T + AQ HA IR+ ++ K A VA + I YGGSV +NA + Q D++G LVGGA+L Sbjct: 181 TAEDAQRIHAQIRAHIAEKSEA-VAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAAL 239 >3UWW-A nrPDB Length = 261 Score = 166 bits (419), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 96/250 (38%), Positives = 135/250 (54%), Gaps = 5/250 (2%) Query: 6 PIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK---FVI 62 PI A NWK N + Q + ++ + + +V+ V+ + + L + K I Sbjct: 12 PIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEI 71 Query: 63 AAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AQN +GAFTGE S L D GV ++V+GHSERR + ET+E + K A G Sbjct: 72 GAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGM 131 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 I C+GET +ERESG+ VV Q+ L + VVIAYEP+WAIGTGK +T + Sbjct: 132 TPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSE 191 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 A E A +R ++ +V+ RI YGGSV N + Q D++G LVGGASLK E Sbjct: 192 DANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVE 251 Query: 242 -FVDIIKATQ 250 FV +++ + Sbjct: 252 DFVQLLEGAK 261 >1YYA-A nrPDB Length = 250 Score = 165 bits (417), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 98/247 (39%), Positives = 136/247 (55%), Gaps = 10/247 (4%) Query: 7 IAAANWKCNGSQQS----LSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 + A NWK + + +EL L + V F L + KE L+ + Sbjct: 5 LVAGNWKMHKTPSEARVWFAELKRLLPPL----QSEAAVLPAFPILPVAKEVLAETQVGY 60 Query: 63 AAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AQ+ A K GA+TGEVS +L D G + ++GHSERR Y+GET+ +VA+K + G Sbjct: 61 GAQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEGI 120 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 I C+GE L+ RE G L Q+ + ++ +VIAYEPVWAIGTGK ATP+ Sbjct: 121 TPILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATPE 180 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 A+ H IR +S + G A +RILYGGSVN KN L +V+G LVGGASL+ E Sbjct: 181 DAEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLELE 240 Query: 242 -FVDIIK 247 F+ +++ Sbjct: 241 SFLALLR 247 >5IBX-C nrPDB Length = 255 Score = 162 bits (411), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 96/253 (37%), Positives = 143/253 (56%), Gaps = 7/253 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHD-VQCVVASTFVHLAMTKERLSHPK 59 MS+ +P A NWK N + + ++ S + D V+ +A+ + L Sbjct: 4 MSR-KPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSN 62 Query: 60 FVIAAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 +AAQN +GAFTGE S +LK+ G +++V+GHSERR Y+ ET+E + K A A Sbjct: 63 LKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFA 122 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 +G + I C GE+L+ E+G+ A V Q++A L A VIAYEP+WAIGTGK A Sbjct: 123 NGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSA 182 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 + AQ+ ++R V++ G +VA ++R+ YGGSV +N + DV+G LVGGASL Sbjct: 183 SQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASL 242 Query: 239 KPE----FVDIIK 247 + E +D +K Sbjct: 243 EAESFLALLDFVK 255 >4NVT-A nrPDB Length = 262 Score = 158 bits (400), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 99/247 (40%), Positives = 140/247 (56%), Gaps = 7/247 (2%) Query: 5 QPIAAANWKCNGSQQSLSEL--IDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 +P+ A NWK NG +SL+EL I S+ + + V+ L+ E L + Sbjct: 14 RPLVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGL 73 Query: 63 AAQNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 Q+A K SGA TG++S +LK+ G ++LGHSERR + E+N+++ K AA A+G Sbjct: 74 GGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGL 133 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + I C+GET ER++ R V+ Q++ A+ +IAYEPVWAIGTG T Q Sbjct: 134 VAIVCVGETASERKAERALDVIGDQLSGSLPDGVTAE--NTIIAYEPVWAIGTGLTPTVQ 191 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-P 240 + AHA +R + + GA A LR+LYGGSV NA L DV+G LVGGASLK Sbjct: 192 DVRAAHAFMREQLIERFGAKGA-HLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAA 250 Query: 241 EFVDIIK 247 +F+ I + Sbjct: 251 DFLAICE 257 >4Y9A-A nrPDB Length = 261 Score = 157 bits (396), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 100/254 (39%), Positives = 138/254 (54%), Gaps = 7/254 (2%) Query: 1 MSKPQPIAAANWKCNGSQ-QSLSELIDL-FNSTSINHD-VQCVVASTFVHLAMTKERLSH 57 M+ P+ A NWK N + ++++ + L F ++D V+ V + F L + + Sbjct: 4 MTTRTPLMAGNWKMNLNHLEAIAHVQKLAFALADKDYDAVEVAVLAPFTDLRSVQTLVDG 63 Query: 58 PKFVI--AAQNAIAKSG-AFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVA 114 K I AQ+ A G A+TGE+S P+L ++ +GHSERR Y+ ET+EIV KV Sbjct: 64 DKLKIKYGAQDISAHDGGAYTGEISGPMLAKLKCTYVAVGHSERRQYHAETDEIVNAKVK 123 Query: 115 AAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGT 174 AA G I C+GE L RE+G L Q+ K L VVIAYEPVWAIGT Sbjct: 124 AAYKHGLTPILCVGEELDVREAGNHVEHTLAQVEGGLKDLAAEQAESVVIAYEPVWAIGT 183 Query: 175 GKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVG 234 GKV AQE A IR ++ ++A ++RI YGGSV N + + D++G LVG Sbjct: 184 GKVCGADDAQEVCAAIRGKLAELYSQELADKVRIQYGGSVKSGNVAEIMAKPDIDGALVG 243 Query: 235 GASLK-PEFVDIIK 247 GASL EFV I++ Sbjct: 244 GASLDSDEFVKIVR 257 >3KXQ-A nrPDB Length = 275 Score = 152 bits (385), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 92/245 (37%), Positives = 136/245 (55%), Gaps = 7/245 (2%) Query: 5 QPIAAANWKCNGSQQSLSEL--IDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 +P A NWK NG+ +SL EL I S+ + + ++ L+ + L ++ Sbjct: 27 RPFIAGNWKMNGTGESLGELRAIAAGISSDLGRLFEALICVPATLLSRAFDILGGENILL 86 Query: 63 AAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 QN G +TG++S +LK+ G + +++GHSERR Y E++ IV KV AA +G Sbjct: 87 GGQNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWRAGL 146 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + + C+GETL+ER+S + V+ Q+ A+ ++IAYEPVWA+GTG AT Sbjct: 147 VALICVGETLEERKSNKVLDVLTRQLEGSLPDGATAE--NIIIAYEPVWAVGTGNTATSA 204 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP- 240 E HA I + S+ G D ++R+LYGGSV NA L VNG L+GGASLK Sbjct: 205 DVAEVHAFIHHKMHSRFG-DEGAKIRLLYGGSVKPSNAFELLSTAHVNGALIGGASLKAI 263 Query: 241 EFVDI 245 +F+ I Sbjct: 264 DFLTI 268 >6BVE-A nrPDB Length = 245 Score = 150 bits (379), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 87/245 (35%), Positives = 135/245 (55%), Gaps = 14/245 (5%) Query: 7 IAAANWKCNGSQQSLSELIDLFNS--TSINHDVQCVVASTFVHLAMTKERLSHPKFVIAA 64 I A NWK + +Q + F + V+ F L+ ++L + + A Sbjct: 8 IIAGNWKMHKTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVRLGA 67 Query: 65 QNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMV 123 QN SGA+TGE+S +L + G++++V+GHSERR Y+GET+E +V AA +G + Sbjct: 68 QNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLAAQKAGLIP 127 Query: 124 IACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQA 183 I C+GE+ +R++G T V++ Q + K L D + +VIAYEP+WAIGTG +A Sbjct: 128 ILCVGESKAQRDAGETEQVIVDQ---VKKGLVNVDQSNLVIAYEPIWAIGTGDTCAATEA 184 Query: 184 QEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE-F 242 LIR +++ ++ I YGGSVN N + Q +++G LVGGASL+P+ F Sbjct: 185 NRVIGLIREQLTNS-------QVTIQYGGSVNANNVDEIMAQPEIDGALVGGASLEPQSF 237 Query: 243 VDIIK 247 I+ Sbjct: 238 ARIVN 242 >3TA6-A nrPDB Length = 267 Score = 143 bits (360), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 99/247 (40%), Positives = 133/247 (53%), Gaps = 7/247 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELID--LFNSTSINHD-VQCVVASTFVHLAMTKERLSH 57 MS+ +P+ A NWK N + L+ F+ +D V V F L + + Sbjct: 1 MSR-KPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDG 59 Query: 58 PKFVI--AAQN-AIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVA 114 K + AQ+ + SGA+TG+VS L G +++V+GHSERR Y+ E + +VA K A Sbjct: 60 DKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAA 119 Query: 115 AAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGT 174 A+ G I CIGE L RE+G + Q+ L VVIAYEPVWAIGT Sbjct: 120 TALKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGT 179 Query: 175 GKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVG 234 G+VA+ AQE A IR ++S +A +R+LYGGSVN KN + Q DV+G LVG Sbjct: 180 GRVASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVG 239 Query: 235 GASLKPE 241 GASL E Sbjct: 240 GASLDGE 246 >4Y90-A nrPDB Length = 247 Score = 138 bits (347), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 97/252 (38%), Positives = 138/252 (54%), Gaps = 9/252 (3%) Query: 2 SKPQPIAAANWKCNGS-QQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 S Q + A NWK N + ++ S +L + V V + + L+ L Sbjct: 2 SHMQTLLALNWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPALDLSALAANLP-AGI 60 Query: 61 VIAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 Q+ A +SGA+TGE+S +LKD G + +V+GHSERR Y+ E++ VA K A A+ Sbjct: 61 AFGGQDVSAHESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDATVAAKARQAQAN 120 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G + I C+GE L RE G L Q+ + + A VV+AYEPVWAIGTGK AT Sbjct: 121 GLLPIVCVGENLDVRERGEHVPQTLAQLRGSLEGVG----ADVVVAYEPVWAIGTGKTAT 176 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 A+E A IR + + GA G +R+LYGGSV +N + + +VNG LVGGASLK Sbjct: 177 ADDAEELAAAIRGALREQYGARAEG-IRVLYGGSVKPENIAEICGKPNVNGALVGGASLK 235 Query: 240 -PEFVDIIKATQ 250 P+ + ++ A + Sbjct: 236 VPDVLGMLDALR 247 >2JGQ-A nrPDB Length = 233 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 65/213 (30%), Positives = 110/213 (51%), Gaps = 28/213 (13%) Query: 28 FNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAKS-GAFTGEVSLPILKDF 86 F+ + D ++ ++F+H F + QNA + GAFTGE++ L++ Sbjct: 33 FDRVFVFPDFFGLLPNSFLH------------FTLGVQNAYPRDCGAFTGEITSKHLEEL 80 Query: 87 GVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQ 146 ++ +++GHSERR E+ + +K + F ++ CIGE L RE G AV Sbjct: 81 KIHTLLIGHSERRTLLKESPSFLKEKFDFFKSKNFKIVYCIGEELTTREKGFKAVKEF-- 138 Query: 147 IAAIAKKLKKAD--WAKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAG 204 ++++L+ D + +V+AYEP+WAIGT K A+ + H ++ ++ K Sbjct: 139 ---LSEQLENIDLNYPNLVVAYEPIWAIGTKKSASLEDIYLTHGFLKQILNQKTP----- 190 Query: 205 ELRILYGGSVNGKNARTLYQQRDVNGFLVGGAS 237 +LYGGSVN +NA+ + V+G L+G AS Sbjct: 191 ---LLYGGSVNTQNAKEILGIDSVDGLLIGSAS 220 >3S6D-A nrPDB Length = 310 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 72/199 (36%), Positives = 103/199 (51%), Gaps = 19/199 (9%) Query: 47 HLAMTKERLSHPKFVIAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGET 105 +LA ++ + P ++ AQ+ S G +TGE+S L+D V+ + LGH+ERRA +GET Sbjct: 99 NLAAPQDADTPPPLLLGAQDCFWDSLGPYTGEISPVCLRDMNVSIVELGHAERRAIFGET 158 Query: 106 NEIVADKVAAAVASGFMVIACIGE-----TLQERESGRTAVVVLTQIAAIAKKLKKADWA 160 ++ VA K AAA G + + CIGE + GR QI + + L + A Sbjct: 159 DQQVARKAAAAADQGLIPLVCIGEVSTLGPIVSEAIGRAVGECEAQIRPVLEALPRD--A 216 Query: 161 KVVIAYEPVWAIGTGKVATPQQAQEAH-----ALIRSWVSSKIGADVAGELRILYGGSVN 215 V+ AYEPVWAIG PQ A+ H + IRS V +I GE+RILYGGS Sbjct: 217 PVIFAYEPVWAIG-----KPQPARVDHVGAVVSGIRS-VIERIDRHRKGEVRILYGGSAG 270 Query: 216 GKNARTLYQQRDVNGFLVG 234 ++V+G +G Sbjct: 271 PGLWGPGGLGKEVDGMFLG 289 >5CSS-A nrPDB Length = 226 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 25/116 (21%) Query: 59 KFVIAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAV 117 KF AQ+ A+ GA+TG V + ++ D G+ +L HSERR + + + + A Sbjct: 54 KFRFFAQHVDAEPYGAYTGHVPMDMMIDLGITGSILNHSERRL----PRDTIINTLKKAS 109 Query: 118 ASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIG 173 F ++ C+ E +E + R ++ IAYEP IG Sbjct: 110 KLDFTIVLCV-ENAEEAKYFR-------------------EYEPDFIAYEPRDLIG 145 >1W0M-A nrPDB Length = 226 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 42/218 (19%) Query: 6 PIAAANWKCNG--SQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIA 63 PI N+K G + + EL + V VVA + L + + + P + Sbjct: 4 PILIINFKAYGEAAGKRAVELAKAAERAARELGVNIVVAPNHLELGLVSQSVDIPVY--- 60 Query: 64 AQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFM 122 AQ A + GA T VSL +K+ G + ++L HSE + +A VA A + G Sbjct: 61 AQGADVEAGGAHTAHVSLENIKEAGGSGVILNHSEAPLKLND----LARLVAKAKSLGLD 116 Query: 123 VIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT--- 179 V+ C + RT+ L A +A EP IGTG+ + Sbjct: 117 VVVCAPDP-------RTS-------------LAAAALGPHAVAVEPPELIGTGRAVSRYK 156 Query: 180 PQQAQEAHALI-RSWVSSKI--------GADVAGELRI 208 P+ E L+ R + + G DVA LR+ Sbjct: 157 PEAIVETVGLVSRHFPEVSVITGAGIESGDDVAAALRL 194 >2H6R-A nrPDB Length = 219 Score = 33.9 bits (76), Expect = 0.064, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Query: 41 VASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRA 100 VA FV L M E ++ P + N G+ TG + +KD G ++ HSE+R Sbjct: 38 VAPQFVDLRMIVENVNIPVYAQHIDNI--NPGSHTGHILAEAIKDCGCKGTLINHSEKRM 95 Query: 101 YYGETNEIV 109 + ++ Sbjct: 96 LLADIEAVI 104 >1HG3-A nrPDB Length = 225 Score = 33.9 bits (76), Expect = 0.072, Method: Compositional matrix adjust. Identities = 38/127 (29%), Positives = 50/127 (39%), Gaps = 14/127 (11%) Query: 5 QPIAAANWKC--NGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 +PI A N+K + + E+ V VVA V L M E + P F Sbjct: 6 EPIIAINFKTYIEATGKRALEIAKAAEKVYKETGVTIVVAPQLVDLRMIAESVEIPVF-- 63 Query: 63 AAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAA---AVAS 119 A K G+ TG V +K+ G +L HSE R I+AD AA A Sbjct: 64 AQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHSENRM-------ILADLEAAIRRAEEV 116 Query: 120 GFMVIAC 126 G M + C Sbjct: 117 GLMTMVC 123 >1GM5-A nrPDB Length = 780 Score = 29.3 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 14/120 (11%) Query: 44 TFVHLAMTKERLSHPKFVI--AAQNAIAKSGAFTGEVSLPILKDFGVNWI-----VLGHS 96 TF HL +ERL++ + + A I K G + I +I L ++ Sbjct: 313 TFYHLEKARERLAYEELFVLQLAFQKIRKEREKHGGIPKKIEGKLAEEFIKSLPFKLTNA 372 Query: 97 ERRAYYGETNEIVADK-----VAAAVASGFMVIACIGETLQERESG-RTAVVVLTQIAAI 150 ++RA+ N+++++K + V SG V+A + L E+G +TA +V T I AI Sbjct: 373 QKRAHQEIRNDMISEKPMNRLLQGDVGSGKTVVAQLA-ILDNYEAGFQTAFMVPTSILAI 431 >5ZBK-A nrPDB Length = 203 Score = 27.7 bits (60), Expect = 4.6, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 101 YYGETNEIVADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAI-AKKLKKADW 159 Y G ++ AA+A+G VI I ++LQE E G + L + + A+K + A+ Sbjct: 40 YGGGAVGLMGTVADAALAAGGEVIGIIPQSLQEAEIGHKGLTRLEVVDGMHARKARMAEL 99 Query: 160 AKVVIA 165 A IA Sbjct: 100 ADAFIA 105 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1KV5-A nrPDB 404 e-113 6NEE-A nrPDB 403 e-113 2VXN-A nrPDB 399 e-112 5CG7-A nrPDB 395 e-111 1CI1-A nrPDB 391 e-109 3Q37-A nrPDB 388 e-108 3TH6-A nrPDB 385 e-107 5ZGA-A nrPDB 379 e-106 2I9E-A nrPDB 379 e-106 4POC-A nrPDB 377 e-105 1SW7-A nrPDB 374 e-104 6CG9-A nrPDB 371 e-103 5EYW-A nrPDB 368 e-102 1MO0-A nrPDB 368 e-102 4OBT-A nrPDB 366 e-102 2V5B-A nrPDB 361 e-100 1TRI-A nrPDB 358 1e-99 4OHQ-A nrPDB 356 7e-99 1B9B-A nrPDB 354 2e-98 1I45-A nrPDB 354 2e-98 2Y70-A nrPDB 353 4e-98 4MKN-A nrPDB 351 2e-97 3PF3-A nrPDB 346 7e-96 3KRS-A nrPDB 346 8e-96 4Y8F-A nrPDB 342 6e-95 4Y96-A nrPDB 340 4e-94 1LZO-A nrPDB 338 1e-93 5UPR-A nrPDB 338 2e-93 1M6J-A nrPDB 337 2e-93 1BTM-A nrPDB 337 3e-93 1TMH-A nrPDB 335 1e-92 5VWN-A nrPDB 333 4e-92 3UWW-A nrPDB 330 3e-91 4Y9A-A nrPDB 324 3e-89 5IBX-C nrPDB 321 2e-88 1YYA-A nrPDB 316 4e-87 5UJW-A nrPDB 308 1e-84 3KXQ-A nrPDB 307 2e-84 4NVT-A nrPDB 301 1e-82 4X22-A nrPDB 299 7e-82 6BVE-A nrPDB 297 3e-81 1AW2-A nrPDB 296 5e-81 4G1K-A nrPDB 295 8e-81 3TA6-A nrPDB 295 1e-80 4Y90-A nrPDB 269 7e-73 2JGQ-A nrPDB 208 2e-54 3S6D-A nrPDB 181 2e-46 5CSS-A nrPDB 106 1e-23 Sequences not found previously or not previously below threshold: 2H6R-A nrPDB 65 3e-11 1HG3-A nrPDB 64 4e-11 1W0M-A nrPDB 61 6e-10 6OKK-M nrPDB 29 1.3 3KW2-A nrPDB 29 1.8 3J1E-A nrPDB 29 2.2 4AF1-A nrPDB 29 2.7 2RUS-A nrPDB 29 2.8 4NNP-A nrPDB 28 3.5 3AGK-A nrPDB 28 3.9 5EMU-A nrPDB 28 4.3 1R6V-A nrPDB 28 4.4 2VOU-A nrPDB 28 5.0 3E70-C nrPDB 28 5.2 4WES-A nrPDB 28 5.4 5FGE-J nrPDB 28 5.6 3WXR-K nrPDB 28 5.6 1RCQ-A nrPDB 28 5.8 2ZXU-A nrPDB 28 6.1 5LZY-jj nrPDB 27 6.5 >1KV5-A nrPDB Length = 250 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 249/250 (99%), Positives = 249/250 (99%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF Sbjct: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 Query: 61 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG Sbjct: 61 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP Sbjct: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QQAQEAHALI SWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP Sbjct: 181 QQAQEAHALISSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 Query: 241 EFVDIIKATQ 250 EFVDIIKATQ Sbjct: 241 EFVDIIKATQ 250 >6NEE-A nrPDB Length = 252 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 135/254 (53%), Positives = 177/254 (69%), Gaps = 6/254 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK- 59 M+ + NWK NG+ +S+ L++ NS ++ + + VVA ++L + +L PK Sbjct: 1 MASRKFFVGGNWKMNGTLESIKALVETLNSAQLDPNTEVVVAPPAIYLPFARSKLKKPKE 60 Query: 60 FVIAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 +AAQN K GAFTGE+S +LKD GV W++LGHSERR +GE++E++A+KV A+ Sbjct: 61 IQVAAQNCYTKPNGAFTGEISAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALD 120 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQI-AAIAKKLKKADWAKVVIAYEPVWAIGTGKV 177 G VIACIGETL+ERE+G+T VV QI AIA K+K DW+ VVIAYEPVWAIGTGKV Sbjct: 121 QGLKVIACIGETLEEREAGKTMEVVARQILKAIADKIK--DWSNVVIAYEPVWAIGTGKV 178 Query: 178 ATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGAS 237 ATP+QAQE HA +R W+ + +VA RI+YGGSVN N + L +Q D++GFLVGGAS Sbjct: 179 ATPEQAQEVHAALRKWLKENVSPEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGAS 238 Query: 238 LK-PEFVDIIKATQ 250 LK PEFVDII A Q Sbjct: 239 LKAPEFVDIINARQ 252 >2VXN-A nrPDB Length = 251 Score = 399 bits (1025), Expect = e-112, Method: Composition-based stats. Identities = 175/249 (70%), Positives = 209/249 (83%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 +KPQPIAAANWKCNG+ S+ +L+ +FN +I+HDVQCVVA TFVH+ + + +L +PK+V Sbjct: 3 AKPQPIAAANWKCNGTTASIEKLVQVFNEHTISHDVQCVVAPTFVHIPLVQAKLRNPKYV 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 I+AQNAIAKSGAFTGEVS+PILKD GV+W++LGHSERR YYGET+EIVA KV+ A GF Sbjct: 63 ISAQNAIAKSGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGF 122 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 MVIACIGETLQ+RE+ +TA VVL+Q +AIA KL K W +VV+AYEPVWAIGTGKVATP+ Sbjct: 123 MVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKVATPE 182 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WVS IG DVA +LRILYGGSVN NA TLY + D+NGFLVGGASLKPE Sbjct: 183 QAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE 242 Query: 242 FVDIIKATQ 250 F DII AT+ Sbjct: 243 FRDIIDATR 251 >5CG7-A nrPDB Length = 271 Score = 395 bits (1015), Expect = e-111, Method: Composition-based stats. Identities = 169/249 (67%), Positives = 206/249 (82%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 +KPQPI AANWKCNG+ S+ +L+ + N I+HDVQCVVA +FVH+ M + +L +PK+ Sbjct: 23 AKPQPIVAANWKCNGTTASIEKLVQVLNEHQIDHDVQCVVAPSFVHIPMVQAKLCNPKYA 82 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 ++A+NAIAKSGAFTGEVS+PILKD GV+W++LGHSERR YYGET+ +VA KVA A GF Sbjct: 83 VSAENAIAKSGAFTGEVSMPILKDLGVSWVILGHSERRTYYGETDGVVAQKVADAYNQGF 142 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 MVIACIGETLQ+RE+ +TA VVL+Q AAIA KL K W+++V+AYEPVWAIGTGKVATP+ Sbjct: 143 MVIACIGETLQQREANQTAKVVLSQTAAIAAKLPKEAWSQIVLAYEPVWAIGTGKVATPE 202 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE HAL+R WVS KIG VA +LRILYGGSV NA+TLY + D+NGFLVGGASLKPE Sbjct: 203 QAQEVHALLRQWVSEKIGNGVATKLRILYGGSVTAGNAKTLYMKPDINGFLVGGASLKPE 262 Query: 242 FVDIIKATQ 250 F DII AT+ Sbjct: 263 FRDIIDATR 271 >1CI1-A nrPDB Length = 251 Score = 391 bits (1004), Expect = e-109, Method: Composition-based stats. Identities = 184/249 (73%), Positives = 216/249 (86%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 SKPQPIAAANWKCNGS+ L LI+ N+ + +HDVQCVVA TF+H+ MTK RL++PKF Sbjct: 3 SKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPKFQ 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 IAAQNAI +SGAFTGEVSL ILKD+G++W+VLGHSERR YYGETNEIVA+KVA A A+GF Sbjct: 63 IAAQNAITRSGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGF 122 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI C+GET +ERE+GRTA VVLTQ+AA+A+KL K W++VVIAYEPVWAIGTGKVATPQ Sbjct: 123 HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQ 182 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WV SK+G D+A +LRILYGGSV KNARTLYQ RD+NGFLVGGASLKPE Sbjct: 183 QAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE 242 Query: 242 FVDIIKATQ 250 FV+II+AT+ Sbjct: 243 FVEIIEATK 251 >3Q37-A nrPDB Length = 251 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 202/249 (81%), Positives = 227/249 (91%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVA TF+H+ MTK RL++PKF Sbjct: 3 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVAPTFLHIPMTKARLTNPKFQ 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 IAAQNAI +SGAFTGEVSL ILKD+G++W+VLGHSERRAYYGETNEIVADKVAAAVASGF Sbjct: 63 IAAQNAITRSGAFTGEVSLQILKDYGISWVVLGHSERRAYYGETNEIVADKVAAAVASGF 122 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI C+GET +ERE+GRTA VVLTQ+AA+A+KL K W++VVIAYEPVWAIGTGKVATPQ Sbjct: 123 HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQ 182 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WV SK+G D+A +LRILYGGSV KNARTLYQ RD+NGFLVGGASLKPE Sbjct: 183 QAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE 242 Query: 242 FVDIIKATQ 250 FV+II+AT+ Sbjct: 243 FVEIIEATK 251 >3TH6-A nrPDB Length = 249 Score = 385 bits (989), Expect = e-107, Method: Composition-based stats. Identities = 122/251 (48%), Positives = 169/251 (67%), Gaps = 4/251 (1%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M+ + NWK +GS+ S+ ++ + S++ +V+ +VA +L + L P Sbjct: 1 MAARRFCVGGNWKMHGSKNSIRDICNTLKGASLDPNVEVIVACPAPYLDYCRSLLP-PSV 59 Query: 61 VIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 +AAQN + GAFTGE+S ++KD G W++LGHSERR + E + ++ +K+ A+ S Sbjct: 60 ALAAQNCYKVEQGAFTGEISPGMIKDCGGQWVILGHSERRHVFKEDDVLIGEKIKHALES 119 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G VIACIGE L++RE+GRT V QI IA +K DW+KVVIAYEPVWAIGTGK AT Sbjct: 120 GLNVIACIGELLEDREAGRTEEVCFRQIKHIASNVK--DWSKVVIAYEPVWAIGTGKTAT 177 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 P QAQE H+ +R+W+S+ + ADVA ++RI YGGSVN N + L ++ D++GFLVGGASLK Sbjct: 178 PDQAQEVHSKVRNWLSTNVSADVASKVRIQYGGSVNAGNCKELGRKPDIDGFLVGGASLK 237 Query: 240 PEFVDIIKATQ 250 PEFV II A Q Sbjct: 238 PEFVQIINAMQ 248 >5ZGA-A nrPDB Length = 269 Score = 379 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 123/251 (49%), Positives = 165/251 (65%), Gaps = 5/251 (1%) Query: 1 MSK-PQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK 59 M + NWK NGS++ +LI++ I+ + + +VA ++L +E+L + Sbjct: 21 MPTDRKFFVGGNWKMNGSKKENDKLIEMLTHAKIDPNTEVLVAPPALYLPSVREKLDK-R 79 Query: 60 FVIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 F +AAQN SGAFTGEVS +LKD G +W++LGHSERR ET+++V +K A A++ Sbjct: 80 FHVAAQNCYKVPSGAFTGEVSPAMLKDVGCDWVILGHSERRHILLETDQLVGEKTAHAIS 139 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 +G VIACIGE L+ERE+G+T V Q+ AI K L W +VIAYEPVWAIGTGK A Sbjct: 140 AGVNVIACIGEKLEEREAGKTEEVCFRQMEAIRKNLS--MWNHIVIAYEPVWAIGTGKTA 197 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 T QQAQE H +R W+ K+ VA +RI+YGGSV N RTL +Q DV+GFLVGGASL Sbjct: 198 TEQQAQEVHLAVRRWMEEKVSPAVAKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASL 257 Query: 239 KPEFVDIIKAT 249 KP+F++I A Sbjct: 258 KPDFIEICNAN 268 >2I9E-A nrPDB Length = 259 Score = 379 bits (973), Expect = e-106, Method: Composition-based stats. Identities = 125/249 (50%), Positives = 165/249 (66%), Gaps = 4/249 (1%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 + + NWK NG ++ ++E+I S +N D + VV ++L + + + + Sbjct: 2 ARKFVVGGNWKMNGDKKQINEIIGFLKSGPLNQDTEVVVGVPAIYLELVRTCVPAS-IGV 60 Query: 63 AAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AAQN GAFTGE+S ++KD G +W++LGHSERR +GE++E++A+KV A+ SG Sbjct: 61 AAQNCYKVPKGAFTGEISPAMIKDVGADWVILGHSERRQIFGESDELIAEKVCHALESGL 120 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VIACIGETL+ERE+G+T VV Q AIA K+ DW+ VVIAYEPVWAIGTGK ATPQ Sbjct: 121 KVIACIGETLEEREAGKTEEVVFRQTKAIAAKVN--DWSNVVIAYEPVWAIGTGKTATPQ 178 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQ+ H +R W+ I A V +RI YGGSV N + L Q D++GFLVGGASLKPE Sbjct: 179 QAQDVHKALRQWICENIDAKVGNSIRIQYGGSVTAANCKELASQPDIDGFLVGGASLKPE 238 Query: 242 FVDIIKATQ 250 FVDII A Q Sbjct: 239 FVDIINARQ 247 >4POC-A nrPDB Length = 254 Score = 377 bits (969), Expect = e-105, Method: Composition-based stats. Identities = 131/250 (52%), Positives = 163/250 (65%), Gaps = 4/250 (1%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 + NWK NG +QSL ELI N+ + D + V A ++ +++L PK Sbjct: 8 PSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIA 66 Query: 62 IAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 +AAQN +GAFTGE+S ++KD G W+VLGHSERR +GE++E++ KVA A+A G Sbjct: 67 VAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEG 126 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 VIACIGE L ERE+G T VV Q IA +K DW+KVV+AYEPVWAIGTGK ATP Sbjct: 127 LGVIACIGEKLDEREAGITEKVVFEQTKVIADNVK--DWSKVVLAYEPVWAIGTGKTATP 184 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QQAQE H +R W+ S + VA RI+YGGSV G + L Q DV+GFLVGGASLKP Sbjct: 185 QQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKP 244 Query: 241 EFVDIIKATQ 250 EFVDII A Q Sbjct: 245 EFVDIINAKQ 254 >1SW7-A nrPDB Length = 248 Score = 374 bits (961), Expect = e-104, Method: Composition-based stats. Identities = 128/251 (50%), Positives = 164/251 (65%), Gaps = 4/251 (1%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M+ + NWK NG ++SL ELI N ++ D + V + ++L +++L K Sbjct: 1 MAPRKFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLD-AKI 59 Query: 61 VIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 +AAQN GAFTGE+S ++KD G W++LGHSERR +GE++E++ KVA A+A Sbjct: 60 GVAAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAE 119 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G VIACIGE L ERE+G T VV Q AIA +K DW+KVV+AYEPVWAIGTG +T Sbjct: 120 GLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVK--DWSKVVLAYEPVWAIGTGNSST 177 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 PQQAQE H +R W+ S + VA RI+YGGSV G N + L Q DV+GFLVGGASLK Sbjct: 178 PQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLK 237 Query: 240 PEFVDIIKATQ 250 PEFVDII A Sbjct: 238 PEFVDIINAKH 248 >6CG9-A nrPDB Length = 256 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 130/249 (52%), Positives = 166/249 (66%), Gaps = 6/249 (2%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKFV 61 + NWKCNG+ + +++ N + V+ VV+ +V L + K +L F Sbjct: 6 RKFFVGGNWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQE-FH 64 Query: 62 IAAQNAIAKSG-AFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 +AAQN K G AFTGEVS +L + GV W++LGHSERRA GE+NE V DKVA A++ G Sbjct: 65 VAAQNCWVKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALSQG 124 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 VIAC+GETL++RE+G T VV Q AIA+K+K DW+ VV+AYEPVWAIGTGKVATP Sbjct: 125 LKVIACVGETLEQREAGSTMDVVAAQTKAIAEKIK--DWSNVVVAYEPVWAIGTGKVATP 182 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QAQE HA +R W+ + +VA RI+YGGSV N + L Q DV+GFLVGGASLKP Sbjct: 183 AQAQEVHASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKP 242 Query: 241 EFVDIIKAT 249 EF+DII A Sbjct: 243 EFIDIINAA 251 >5EYW-A nrPDB Length = 249 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 110/249 (44%), Positives = 160/249 (64%), Gaps = 4/249 (1%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 S + NWK NG + ++ +I + ++ + + VV +L T+E + Sbjct: 3 SPRKFFVGGNWKMNGDKAAIDGIISFMKTGPLSPNTEVVVGCPQCYLMYTREHMP-ANIG 61 Query: 62 IAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 IAAQN GAFTGE+S ++KD G W++LGHSERR +GE ++++++KV A+ +G Sbjct: 62 IAAQNCYKVAKGAFTGEISPAMVKDCGCEWVILGHSERRNVFGEPDQLISEKVGHALEAG 121 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 VI CIGE L++RE RT VV Q+ A+ + DW++VV+AYEPVWAIGTGK A+P Sbjct: 122 LKVIPCIGEKLEDREGNRTQEVVFAQMKALLPNIS--DWSRVVLAYEPVWAIGTGKTASP 179 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 +QAQE HA +R W+ + A+VA RI+YGGSV+ N + L ++ D++GFLVGGA+LKP Sbjct: 180 EQAQEVHADLRQWLRDNVNAEVAESTRIIYGGSVSAGNCQELAKKGDIDGFLVGGAALKP 239 Query: 241 EFVDIIKAT 249 +FV II A Sbjct: 240 DFVQIINAR 248 >1MO0-A nrPDB Length = 275 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 113/248 (45%), Positives = 155/248 (62%), Gaps = 4/248 (1%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 + NWK NG S+ ++ N+++ N V VVA +LA K +L ++ Sbjct: 22 TRKFFVGGNWKMNGDYASVDGIVTFLNASADNSSVDVVVAPPAPYLAYAKSKLK-AGVLV 80 Query: 63 AAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AAQN GAFTGE+S ++KD G+ W++LGHSERR +GE++ ++A+K A+ +G Sbjct: 81 AAQNCYKVPKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHALEAGI 140 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 V+ CIGE L+ERE+G T V Q+ AI K W +VIAYEPVWAIGTGK A+ + Sbjct: 141 KVVFCIGEKLEEREAGHTKDVNFRQLQAIVD--KGVSWENIVIAYEPVWAIGTGKTASGE 198 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H IR+++ K+ VA RI+YGGSV NA L ++ D++GFLVGGASLKP+ Sbjct: 199 QAQEVHEWIRAFLKEKVSPAVADATRIIYGGSVTADNAAELGKKPDIDGFLVGGASLKPD 258 Query: 242 FVDIIKAT 249 FV II A Sbjct: 259 FVKIINAR 266 >4OBT-A nrPDB Length = 257 Score = 366 bits (940), Expect = e-102, Method: Composition-based stats. Identities = 129/251 (51%), Positives = 167/251 (66%), Gaps = 6/251 (2%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKF 60 + NWKCNG+ + + ++++ N + V+ VV+ +V L + K L F Sbjct: 5 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDF 63 Query: 61 VIAAQNAIAKSG-AFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 +AAQN K G AFTGEVS +L + + W++LGHSERRA E++E V DKVA A+A Sbjct: 64 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 123 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G VIAC+GETL+ERE+G T VV Q AIA ++ W+ VVIAYEPVWAIGTGKVA+ Sbjct: 124 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVAS 181 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 P QAQE H +R W++ + ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLK Sbjct: 182 PAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK 241 Query: 240 PEFVDIIKATQ 250 PEF+DIIKA + Sbjct: 242 PEFIDIIKAAE 252 >2V5B-A nrPDB Length = 244 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 173/249 (69%), Positives = 205/249 (82%), Gaps = 7/249 (2%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 SKPQPIAAANWKCNGS+ L LI+ N+ + +HDVQCVVA TF+H+ MTK RL++PKF Sbjct: 3 SKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPKFQ 62 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 IAAQNA +L LKD+G++W+VLGHSERR YYGETNEIVA+KVA A A+GF Sbjct: 63 IAAQNAGNAD-------ALASLKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGF 115 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI C+GET +ERE+GRTA VVLTQ+AA+A+KL K W++VVIAYEPVWAIGTGKVATPQ Sbjct: 116 HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQ 175 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQE H L+R WV SK+G D+A +LRILYGGSV KNARTLYQ RD+NGFLVGGASLKPE Sbjct: 176 QAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE 235 Query: 242 FVDIIKATQ 250 FV+II+AT+ Sbjct: 236 FVEIIEATK 244 >1TRI-A nrPDB Length = 243 Score = 358 bits (919), Expect = 1e-99, Method: Composition-based stats. Identities = 236/250 (94%), Positives = 237/250 (94%), Gaps = 7/250 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF Sbjct: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 Query: 61 VIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 VIAAQNA +L LKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG Sbjct: 61 VIAAQNAGNAD-------ALASLKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 113 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP Sbjct: 114 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 173 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP Sbjct: 174 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 233 Query: 241 EFVDIIKATQ 250 EFVDIIKATQ Sbjct: 234 EFVDIIKATQ 243 >4OHQ-A nrPDB Length = 256 Score = 356 bits (913), Expect = 7e-99, Method: Composition-based stats. Identities = 119/249 (47%), Positives = 163/249 (65%), Gaps = 5/249 (2%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 + NWKCNG++ S+++LI NS ++ DV VV+ FV++ K L+ + Sbjct: 3 GSGKFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLT-DRID 61 Query: 62 IAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 I+ QN+ K GAFTGE+S+ LKD G W++LGHSERR GE +E + K A A++ G Sbjct: 62 ISGQNSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEG 121 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 VIACIGE L+ERE+G+T V Q+ A A + W +V+AYEPVWAIGTGKVA+P Sbjct: 122 LGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVPS--WDNIVVAYEPVWAIGTGKVASP 179 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK- 239 QQAQE H +R W+ + +VA + RI+YGGSVNG N+ L ++ D++GFLVGGASLK Sbjct: 180 QQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKG 239 Query: 240 PEFVDIIKA 248 PEF I+ + Sbjct: 240 PEFATIVNS 248 >1B9B-A nrPDB Length = 255 Score = 354 bits (909), Expect = 2e-98, Method: Composition-based stats. Identities = 106/250 (42%), Positives = 146/250 (58%), Gaps = 2/250 (0%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLF-NSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 + I A NWK + + + + L N + + VV F L+ E LS Sbjct: 2 TRKLILAGNWKMHKTISEAKKFVSLLVNELHDVKEFEIVVCPPFTALSEVGEILSGRNIK 61 Query: 62 IAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 + AQN + GAFTGE+S +L++ GV ++++GHSERR + E +E + KV A + G Sbjct: 62 LGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLEKG 121 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 I C+GETL+ERE G T VV Q+ L K + +VVIAYEPVWAIGTG+VATP Sbjct: 122 MTPILCVGETLEEREKGLTFCVVEKQVREGFYGLDKEEAKRVVIAYEPVWAIGTGRVATP 181 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 QQAQE HA IR +S + AG +RILYGGS+ N L Q+D++G LVGGASLK Sbjct: 182 QQAQEVHAFIRKLLSEMYDEETAGSIRILYGGSIKPDNFLGLIVQKDIDGGLVGGASLKE 241 Query: 241 EFVDIIKATQ 250 F+++ + + Sbjct: 242 SFIELARIMR 251 >1I45-A nrPDB Length = 248 Score = 354 bits (908), Expect = 2e-98, Method: Composition-based stats. Identities = 121/248 (48%), Positives = 168/248 (67%), Gaps = 3/248 (1%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 N+K NGS+QS+ E+++ N+ SI +V+ V+ +L + + P+ + Sbjct: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 Query: 63 AAQNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AQNA K SGAFTGE S+ +KD G +++LGHSERR+Y+ E ++ +ADK A+ G Sbjct: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKYVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 VI CIGETL+E+++G+T VV Q+ A+ +++K D+ VV+AYEPVWAIGTG ATP+ Sbjct: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVK--DFTNVVVAYEPVWAIGTGLAATPE 179 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 AQ+ HA IR +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPE Sbjct: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 Query: 242 FVDIIKAT 249 FVDII + Sbjct: 240 FVDIINSR 247 >2Y70-A nrPDB Length = 245 Score = 353 bits (906), Expect = 4e-98, Method: Composition-based stats. Identities = 222/252 (88%), Positives = 230/252 (91%), Gaps = 9/252 (3%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVH--LAMTKERLSHP 58 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVA ++ AMTKERLSHP Sbjct: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVAPSWYMGAQAMTKERLSHP 60 Query: 59 KFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 KFVIAAQNA +L LKDFG++WIVL HSERRAYYGETNEIVADKVAAAVA Sbjct: 61 KFVIAAQNAGNAD-------ALASLKDFGISWIVLDHSERRAYYGETNEIVADKVAAAVA 113 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 SGFMVIACIGETLQER SGRTAVVVLTQI AIAKKLKKADWAKVVIAYEPVWAIGTGKVA Sbjct: 114 SGFMVIACIGETLQERSSGRTAVVVLTQITAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 173 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 TPQQAQEAHALIRSWVSSK+GADVAGELRILYGGSVNG+NARTLYQQRDVNGFLVGGASL Sbjct: 174 TPQQAQEAHALIRSWVSSKVGADVAGELRILYGGSVNGRNARTLYQQRDVNGFLVGGASL 233 Query: 239 KPEFVDIIKATQ 250 KPEFVDIIKAT+ Sbjct: 234 KPEFVDIIKATE 245 >4MKN-A nrPDB Length = 270 Score = 351 bits (900), Expect = 2e-97, Method: Composition-based stats. Identities = 127/250 (50%), Positives = 173/250 (69%), Gaps = 4/250 (1%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 S + NWKCNGS ++++L+D N+ +I V VVA F+++ + L K+ Sbjct: 17 SSAKFFVGGNWKCNGSVANVAKLVDELNAGTIPRGVDVVVAPPFIYIDYVMQHLDRDKYQ 76 Query: 62 IAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 ++AQNA +GAFTGEVS L DFGV W++LGHSERR+ +GE+NE+VA K + A+A+G Sbjct: 77 LSAQNAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAG 136 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 VIACIGETL++R SG V+ Q+ A+ ++K DW KVV+AYEPVWAIGTG VA+P Sbjct: 137 LGVIACIGETLEQRNSGSVFKVLDAQMDALVDEVK--DWTKVVLAYEPVWAIGTGVVASP 194 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK- 239 +QAQE HA +R + + K+GA VA +LRI+YGGSV+ N + L +Q D++GFLVGGASLK Sbjct: 195 EQAQEVHAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKG 254 Query: 240 PEFVDIIKAT 249 FV I A Sbjct: 255 AAFVTICNAA 264 >3PF3-A nrPDB Length = 257 Score = 346 bits (887), Expect = 7e-96, Method: Composition-based stats. Identities = 111/250 (44%), Positives = 157/250 (62%), Gaps = 3/250 (1%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M +P N+KCNGS + + + I V V+A + VHL+ + + Sbjct: 1 MPARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIPDSVDVVIAPSAVHLSTAIAANTSKQL 60 Query: 61 VIAAQNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 IAAQN + +GA+TGE S+ +L+D G+ +++GHSERR GET+E A K A+ Sbjct: 61 RIAAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEK 120 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKAD--WAKVVIAYEPVWAIGTGKV 177 G VI C+GETL ER++ RT V + Q+ A+ K+L ++ W +VVIAYEPVW+IGTG V Sbjct: 121 GMTVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVV 180 Query: 178 ATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGAS 237 ATP+QA+E H +R W + K+ A+ A +RI+YGGS NG N L Q +++GFLVGGAS Sbjct: 181 ATPEQAEEVHVGLRKWFAEKVAAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGAS 240 Query: 238 LKPEFVDIIK 247 LKPEF+ +I Sbjct: 241 LKPEFMTMID 250 >3KRS-A nrPDB Length = 271 Score = 346 bits (887), Expect = 8e-96, Method: Composition-based stats. Identities = 114/252 (45%), Positives = 158/252 (62%), Gaps = 7/252 (2%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK--- 59 + N+KCNG+++SL LID F + + + V T +H+++ KE + Sbjct: 23 SRKYFVGGNFKCNGTKESLKTLIDSFKQVE-SSNSEVYVFPTSLHISLVKEFFGNDHPGV 81 Query: 60 FVIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 F I +QN +GAFTGEVS +LKD V+ ++GHSERR YY ET++IV +KV + Sbjct: 82 FKIGSQNISCTGNGAFTGEVSCEMLKDMDVDCSLVGHSERRQYYSETDQIVNNKVKKGLE 141 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 +G ++ CIGE+L ERE+G+T V+ Q+ K + D + +VIAYEP+WAIGTG VA Sbjct: 142 NGLKIVLCIGESLSERETGKTNDVIQKQLTEALKDVS--DLSNLVIAYEPIWAIGTGVVA 199 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 TP QAQEAHA IR +V+ V+ LRI+YGGSV N L + D++GFLVGGASL Sbjct: 200 TPGQAQEAHAFIREYVTRMYNPQVSSNLRIIYGGSVTPDNCNELIKCADIDGFLVGGASL 259 Query: 239 KPEFVDIIKATQ 250 KP F II++ Q Sbjct: 260 KPTFAKIIESAQ 271 >4Y8F-A nrPDB Length = 251 Score = 342 bits (879), Expect = 6e-95, Method: Composition-based stats. Identities = 100/246 (40%), Positives = 139/246 (56%), Gaps = 2/246 (0%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIA 63 PI A NWK + + +L++ + + VV TFV L K+ + + Sbjct: 5 RTPIIAGNWKMHYTIDEAVKLVEELKPLVKDAKCEVVVCPTFVCLDAVKKAVEGTNIKVG 64 Query: 64 AQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFM 122 AQN + GAFTGE++ +L+ ++++++GHSERR Y+ ET+E KV AA A Sbjct: 65 AQNMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHNLT 124 Query: 123 VIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQ 182 I C GETL++RE+G T V+ QI A + L K KVVIAYEP+WAIGTGK AT Q Sbjct: 125 PILCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATSDQ 184 Query: 183 AQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL-KPE 241 A E A IR+ V+ G +VA ++RI YGGSV + D++G LVGGASL + Sbjct: 185 ANETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASLVAAD 244 Query: 242 FVDIIK 247 F I+ Sbjct: 245 FAQIVN 250 >4Y96-A nrPDB Length = 255 Score = 340 bits (872), Expect = 4e-94, Method: Composition-based stats. Identities = 104/251 (41%), Positives = 133/251 (52%), Gaps = 2/251 (0%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 M + A NWK N + L + V V + L E L Sbjct: 4 MPTRKKFVAGNWKMNTTLAEAKALGAAVAKGVTDDRVTVAVFPPYPWLTAVGEVLKGSPV 63 Query: 61 VIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 + AQ+ K GAFTGEVS +L + G + ++GHSERR GE+ + KV A+ Sbjct: 64 ALGAQDVSSEKKGAFTGEVSPAMLLETGCKYALIGHSERRHIIGESETFINHKVHTALEE 123 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G V+ C+GETL ERE G V Q+ A L + ++VIAYEPVWAIGTGKVAT Sbjct: 124 GLSVVLCMGETLAERERGLQERVFQRQVYAACAGLTDEQFGRIVIAYEPVWAIGTGKVAT 183 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 P+QAQEAHA +RS + G +A I+YGGSV N L Q DV+G LVGGASLK Sbjct: 184 PEQAQEAHAFVRSKLRLLYGDKIADSTPIVYGGSVTPDNTVGLMSQPDVDGALVGGASLK 243 Query: 240 PE-FVDIIKAT 249 + F+ I+KA Sbjct: 244 ADSFLAIVKAA 254 >1LZO-A nrPDB Length = 248 Score = 338 bits (867), Expect = 1e-93, Method: Composition-based stats. Identities = 106/249 (42%), Positives = 150/249 (60%), Gaps = 5/249 (2%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINH-DVQCVVASTFVHLAMTKERLSHPKFV 61 + AANWKCNG+ +S+ L + FN+ + + VV VH T++ L KF Sbjct: 2 ARKYFVAANWKCNGTLESIKSLTNSFNNLDFDPSKLDVVVFPVSVHYDHTRKLL-QSKFS 60 Query: 62 IAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 QN +G++TGEVS I KD + ++++GH ERR Y+ ET+E V +K+ A++ + Sbjct: 61 TGIQNVSKFGNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLKNN 120 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 + C GE+L++RE +T V+ Q+ A + D V++ YEP+WAIGTGK ATP Sbjct: 121 LKAVVCFGESLEQREQNKTIEVITKQVKAFVDLIDNFD--NVILVYEPLWAIGTGKTATP 178 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 +QAQ H IR V G A ++RILYGGSVN +N +L QQ D++GFLVG ASLK Sbjct: 179 EQAQLVHKEIRKIVKDTCGEKQANQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASLKE 238 Query: 241 EFVDIIKAT 249 FVDIIK+ Sbjct: 239 SFVDIIKSA 247 >5UPR-A nrPDB Length = 265 Score = 338 bits (867), Expect = 2e-93, Method: Composition-based stats. Identities = 119/257 (46%), Positives = 168/257 (65%), Gaps = 8/257 (3%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSIN-HDVQCVVASTFVHLAMTKERLSHPKF 60 + + NWKCNG+ EL+D+ NS ++ V VVA + ++ ++ L P+ Sbjct: 6 AARRGFVGGNWKCNGTTAKTQELVDMLNSAPVSFEQVDVVVAPPSLFISQVQDSLRQPRV 65 Query: 61 VIAAQNAIAKS--GAFTGEVSLPILKDFGVNWIVLGHSERRAYYG----ETNEIVADKVA 114 +AAQ++ + GAFTGE+S ++K+ + W+VLGHSERRA +G E+N++VA KV Sbjct: 66 QVAAQDSSTQQAYGAFTGELSPKMIKEKNIPWVVLGHSERRAGFGGQPGESNQVVAKKVR 125 Query: 115 AAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKAD-WAKVVIAYEPVWAIG 173 AA+ G VI CIGETL+ERESG+T V+ Q+ A+ + + +AD W +VIAYEPVWAIG Sbjct: 126 AALNEGLSVILCIGETLEERESGQTQKVLSEQLEAVRQAVPEADAWKSIVIAYEPVWAIG 185 Query: 174 TGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLV 233 TGK AT AQE H IR+W++ + VA R++YGGSV G NA+ L++ DV+GFLV Sbjct: 186 TGKTATAALAQETHRDIRNWLAQAVSPKVAEATRVIYGGSVKGSNAKELFEGEDVDGFLV 245 Query: 234 GGASLKPEFVDIIKATQ 250 GGASL +FV II A + Sbjct: 246 GGASLTGDFVSIIDAAK 262 >1M6J-A nrPDB Length = 261 Score = 337 bits (866), Expect = 2e-93, Method: Composition-based stats. Identities = 109/256 (42%), Positives = 155/256 (60%), Gaps = 8/256 (3%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNS---TSINHDVQCVVASTFVHLAMTKERLSH 57 M + + NWKCNG+ S+ L + + V+ +V F+++ ++ L+ Sbjct: 1 MGAGKFVVGGNWKCNGTLASIETLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQILAG 60 Query: 58 P----KFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKV 113 +++A+NA KSGA+TGEV + +L D V +++LGHSERR + E+NE VA+KV Sbjct: 61 EANGANILVSAENAWTKSGAYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVAEKV 120 Query: 114 AAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIG 173 A+ +G VIACIGET +R + +T VV Q+ AI + K W +++AYEPVWAIG Sbjct: 121 KVAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVWAIG 180 Query: 174 TGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLV 233 TGK ATP QAQE H IR W++ I +VA RI YGGSVN N L ++ D++GFLV Sbjct: 181 TGKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDGFLV 240 Query: 234 GGASLK-PEFVDIIKA 248 GGASL +F II + Sbjct: 241 GGASLDAAKFKTIINS 256 >1BTM-A nrPDB Length = 252 Score = 337 bits (865), Expect = 3e-93, Method: Composition-based stats. Identities = 102/250 (40%), Positives = 140/250 (56%), Gaps = 3/250 (1%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNSTSINHD-VQCVVASTFVHLAMTKERLSHPKFVI 62 +PI A NWK + + + ++ D V VV + F+ L + I Sbjct: 1 RKPIIAGNWKMHKTLAEAVQFVEDVKGHVPPADEVISVVCAPFLFLDRLVQAADGTDLKI 60 Query: 63 AAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AQ A GA+TGEVS +LKD GV +++LGHSERR + ET+E V KV AA G Sbjct: 61 GAQTMHFADQGAYTGEVSPVMLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRGL 120 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + I C GE+L+ERE+G+T VV +Q+ L + VIAYEP+WAIGTGK +TP+ Sbjct: 121 IPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQAVIAYEPIWAIGTGKSSTPE 180 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP- 240 A IRS VS G + A +RI YGGSV N R Q+ ++G LVGGASL+P Sbjct: 181 DANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGPLVGGASLEPA 240 Query: 241 EFVDIIKATQ 250 F+ +++A + Sbjct: 241 SFLQLVEAGR 250 >1TMH-A nrPDB Length = 254 Score = 335 bits (860), Expect = 1e-92, Method: Composition-based stats. Identities = 114/249 (45%), Positives = 150/249 (60%), Gaps = 3/249 (1%) Query: 4 PQPIAAANWKCNGSQQSLSELI-DLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 P+ NWK NGS+ + EL+ +L + +A +++ M K ++ Sbjct: 2 RHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIML 61 Query: 63 AAQNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 AQN SGAFTGE S +LKD G +I++GHSERR Y+ E++E++A K A G Sbjct: 62 GAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGL 121 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + CIGET E E+G+T V QI A+ K A + VIAYEPVWAIGTGK ATP Sbjct: 122 TPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPA 181 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 QAQ H IR ++ K+ A++A ++ I YGGSVN NA L+ Q DV+GFLVGGASLKPE Sbjct: 182 QAQAVHKFIRDHIA-KVDANIAEQVIIQYGGSVNASNAAELFAQHDVDGFLVGGASLKPE 240 Query: 242 FVDIIKATQ 250 FVDII A + Sbjct: 241 FVDIINAAE 249 >5VWN-A nrPDB Length = 246 Score = 333 bits (855), Expect = 4e-92, Method: Composition-based stats. Identities = 99/247 (40%), Positives = 147/247 (59%), Gaps = 7/247 (2%) Query: 4 PQPIAAANWKCN-GSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 NWK N + Q +L+++ N + +V+ VVA+ FV L +++L + + Sbjct: 2 RTFFVGGNWKANPKTVQEAEKLVEMLNGAKVEGNVEVVVAAPFVFLPTLQQKLRK-DWKV 60 Query: 63 AAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFM 122 +A+N K ++P++K FG+ W +LGHSERR E +E +A K A+ +G Sbjct: 61 SAENVFTKPNG-----TVPMIKSFGIEWTILGHSERRDILKEDDEFLAAKAKFALENGMK 115 Query: 123 VIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQ 182 +I C GE L ERE+G+ + V QI + + W VVIAYEP+WAIGTGKVA+ Q Sbjct: 116 IIYCCGEHLSEREAGKASEFVSAQIEKMIPAIPAGKWDDVVIAYEPIWAIGTGKVASTQD 175 Query: 183 AQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEF 242 AQE +IR +++K+GAD+A ++RILYGGSV N L DV+GFLVGGASL+ F Sbjct: 176 AQEMCKVIRDILAAKVGADIANKVRILYGGSVKPNNCNELAACPDVDGFLVGGASLEAGF 235 Query: 243 VDIIKAT 249 ++I+ + Sbjct: 236 INIVNSN 242 >3UWW-A nrPDB Length = 261 Score = 330 bits (847), Expect = 3e-91, Method: Composition-based stats. Identities = 96/254 (37%), Positives = 136/254 (53%), Gaps = 5/254 (1%) Query: 2 SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK-- 59 S PI A NWK N + Q + ++ + + +V+ V+ + + L + K Sbjct: 8 SMRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQ 67 Query: 60 -FVIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAV 117 I AQN +GAFTGE S L D GV ++V+GHSERR + ET+E + K A Sbjct: 68 GLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIF 127 Query: 118 ASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKV 177 G I C+GET +ERESG+ VV Q+ L + VVIAYEP+WAIGTGK Sbjct: 128 KHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKS 187 Query: 178 ATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGAS 237 +T + A E A +R ++ +V+ RI YGGSV N + Q D++G LVGGAS Sbjct: 188 STSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGAS 247 Query: 238 LK-PEFVDIIKATQ 250 LK +FV +++ + Sbjct: 248 LKVEDFVQLLEGAK 261 >4Y9A-A nrPDB Length = 261 Score = 324 bits (830), Expect = 3e-89, Method: Composition-based stats. Identities = 98/254 (38%), Positives = 131/254 (51%), Gaps = 7/254 (2%) Query: 1 MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHD---VQCVVASTFVHLAMTKERLSH 57 M+ P+ A NWK N + + + D V+ V + F L + + Sbjct: 4 MTTRTPLMAGNWKMNLNHLEAIAHVQKLAFALADKDYDAVEVAVLAPFTDLRSVQTLVDG 63 Query: 58 PKFVI--AAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVA 114 K I AQ+ A GA+TGE+S P+L ++ +GHSERR Y+ ET+EIV KV Sbjct: 64 DKLKIKYGAQDISAHDGGAYTGEISGPMLAKLKCTYVAVGHSERRQYHAETDEIVNAKVK 123 Query: 115 AAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGT 174 AA G I C+GE L RE+G L Q+ K L VVIAYEPVWAIGT Sbjct: 124 AAYKHGLTPILCVGEELDVREAGNHVEHTLAQVEGGLKDLAAEQAESVVIAYEPVWAIGT 183 Query: 175 GKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVG 234 GKV AQE A IR ++ ++A ++RI YGGSV N + + D++G LVG Sbjct: 184 GKVCGADDAQEVCAAIRGKLAELYSQELADKVRIQYGGSVKSGNVAEIMAKPDIDGALVG 243 Query: 235 GASLKP-EFVDIIK 247 GASL EFV I++ Sbjct: 244 GASLDSDEFVKIVR 257 >5IBX-C nrPDB Length = 255 Score = 321 bits (823), Expect = 2e-88, Method: Composition-based stats. Identities = 93/248 (37%), Positives = 141/248 (56%), Gaps = 3/248 (1%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSINHD-VQCVVASTFVHLAMTKERLSHPKFV 61 +P A NWK N + + ++ S + D V+ +A+ + L Sbjct: 5 SRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNLK 64 Query: 62 IAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 +AAQN ++ GAFTGE S +LK+ G +++V+GHSERR Y+ ET+E + K A A+G Sbjct: 65 VAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFANG 124 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 + I C GE+L+ E+G+ A V Q++A L A VIAYEP+WAIGTGK A+ Sbjct: 125 MLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSASQ 184 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 AQ+ ++R V++ G +VA ++R+ YGGSV +N + DV+G LVGGASL+ Sbjct: 185 DDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLEA 244 Query: 241 E-FVDIIK 247 E F+ ++ Sbjct: 245 ESFLALLD 252 >1YYA-A nrPDB Length = 250 Score = 316 bits (811), Expect = 4e-87, Method: Composition-based stats. Identities = 95/246 (38%), Positives = 133/246 (54%), Gaps = 2/246 (0%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIA 63 + + A NWK + + + V F L + KE L+ + Sbjct: 2 RRVLVAGNWKMHKTPSEARVWFAELKRLLPPLQSEAAVLPAFPILPVAKEVLAETQVGYG 61 Query: 64 AQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFM 122 AQ+ A K GA+TGEVS +L D G + ++GHSERR Y+GET+ +VA+K + G Sbjct: 62 AQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEGIT 121 Query: 123 VIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQ 182 I C+GE L+ RE G L Q+ + ++ +VIAYEPVWAIGTGK ATP+ Sbjct: 122 PILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATPED 181 Query: 183 AQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE- 241 A+ H IR +S + G A +RILYGGSVN KN L +V+G LVGGASL+ E Sbjct: 182 AEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLELES 241 Query: 242 FVDIIK 247 F+ +++ Sbjct: 242 FLALLR 247 >5UJW-A nrPDB Length = 253 Score = 308 bits (790), Expect = 1e-84, Method: Composition-based stats. Identities = 96/249 (38%), Positives = 147/249 (59%), Gaps = 5/249 (2%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNSTSIN-HDVQCVVASTFVHLAMTKERLSHPKFVI 62 Q + NWK NG+ S+ EL + + V V + V++ +L K + Sbjct: 1 MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLP-EKVGV 59 Query: 63 AAQN-AIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 QN GA+TGE+S +L+D G +++++GHSERR+ + E++E V K+ + + Sbjct: 60 GLQNITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTI 119 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + CIGE+L +R+SG+ V+ TQ++ I + L AKVVIAYEPVWAIGTG VA+ + Sbjct: 120 TPVVCIGESLDDRQSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLE 179 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-P 240 Q QE H IRS ++ K+ +A ++I+YGGS+ +NA+ + DV+G L+GGASLK Sbjct: 180 QIQETHQFIRSLLA-KVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAA 238 Query: 241 EFVDIIKAT 249 EF +II Sbjct: 239 EFNEIINQA 247 >3KXQ-A nrPDB Length = 275 Score = 307 bits (788), Expect = 2e-84, Method: Composition-based stats. Identities = 92/250 (36%), Positives = 137/250 (54%), Gaps = 7/250 (2%) Query: 2 SKPQPIAAANWKCNGSQQSLSEL--IDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPK 59 +P A NWK NG+ +SL EL I S+ + + ++ L+ + L Sbjct: 24 PNIRPFIAGNWKMNGTGESLGELRAIAAGISSDLGRLFEALICVPATLLSRAFDILGGEN 83 Query: 60 FVIAAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVA 118 ++ QN G +TG++S +LK+ G + +++GHSERR Y E++ IV KV AA Sbjct: 84 ILLGGQNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWR 143 Query: 119 SGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVA 178 +G + + C+GETL+ER+S + V+ Q+ A+ ++IAYEPVWA+GTG A Sbjct: 144 AGLVALICVGETLEERKSNKVLDVLTRQLEGSLPDGATAE--NIIIAYEPVWAVGTGNTA 201 Query: 179 TPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 T E HA I + S+ G + A ++R+LYGGSV NA L VNG L+GGASL Sbjct: 202 TSADVAEVHAFIHHKMHSRFGDEGA-KIRLLYGGSVKPSNAFELLSTAHVNGALIGGASL 260 Query: 239 KP-EFVDIIK 247 K +F+ I Sbjct: 261 KAIDFLTICD 270 >4NVT-A nrPDB Length = 262 Score = 301 bits (772), Expect = 1e-82, Method: Composition-based stats. Identities = 99/250 (39%), Positives = 141/250 (56%), Gaps = 7/250 (2%) Query: 5 QPIAAANWKCNGSQQSLSEL--IDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVI 62 +P+ A NWK NG +SL+EL I S+ + + V+ L+ E L + Sbjct: 14 RPLVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGL 73 Query: 63 AAQNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 Q+A K SGA TG++S +LK+ G ++LGHSERR + E+N+++ K AA A+G Sbjct: 74 GGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGL 133 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 + I C+GET ER++ R V+ Q++ A+ +IAYEPVWAIGTG T Q Sbjct: 134 VAIVCVGETASERKAERALDVIGDQLSGSLPDGVTAE--NTIIAYEPVWAIGTGLTPTVQ 191 Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK-P 240 + AHA +R + + GA A LR+LYGGSV NA L DV+G LVGGASLK Sbjct: 192 DVRAAHAFMREQLIERFGAKGA-HLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAA 250 Query: 241 EFVDIIKATQ 250 +F+ I + + Sbjct: 251 DFLAICETYR 260 >4X22-A nrPDB Length = 250 Score = 299 bits (767), Expect = 7e-82, Method: Composition-based stats. Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 5/241 (2%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLF--NSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 + I A NWK N S + L SI+ D +V + +HL + L + Sbjct: 2 RKTIIAGNWKMNLSLKEAVFLAHSIREKIPSISKDKVSMVFPSTLHLENVSKILEGSSVI 61 Query: 62 IAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 + AQN AFTGE S LK+ GV +++GHSERR + GE+N DK+ + + Sbjct: 62 VGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLLKNE 121 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 F V+ C+GETL ERESG+T V+ +QI K + ++ +++AYEPVWAIGTGKVATP Sbjct: 122 FTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKVATP 181 Query: 181 QQAQEAHALIRSWVSSKI--GADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASL 238 QAQE H+ IR +S + ++ + ILYGGSV N + L +++D++G LVGGAS Sbjct: 182 SQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGGASQ 241 Query: 239 K 239 K Sbjct: 242 K 242 >6BVE-A nrPDB Length = 245 Score = 297 bits (761), Expect = 3e-81, Method: Composition-based stats. Identities = 87/248 (35%), Positives = 137/248 (55%), Gaps = 14/248 (5%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNST--SINHDVQCVVASTFVHLAMTKERLSHPKFV 61 + I A NWK + +Q + F + V+ F L+ ++L + Sbjct: 5 RKIIIAGNWKMHKTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVR 64 Query: 62 IAAQNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASG 120 + AQN + SGA+TGE+S +L + G++++V+GHSERR Y+GET+E +V AA +G Sbjct: 65 LGAQNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLAAQKAG 124 Query: 121 FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 180 + I C+GE+ +R++G T V++ Q+ K L D + +VIAYEP+WAIGTG Sbjct: 125 LIPILCVGESKAQRDAGETEQVIVDQVK---KGLVNVDQSNLVIAYEPIWAIGTGDTCAA 181 Query: 181 QQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKP 240 +A LIR +++ ++ I YGGSVN N + Q +++G LVGGASL+P Sbjct: 182 TEANRVIGLIREQLTN-------SQVTIQYGGSVNANNVDEIMAQPEIDGALVGGASLEP 234 Query: 241 E-FVDIIK 247 + F I+ Sbjct: 235 QSFARIVN 242 >1AW2-A nrPDB Length = 256 Score = 296 bits (759), Expect = 5e-81, Method: Composition-based stats. Identities = 92/240 (38%), Positives = 135/240 (56%), Gaps = 5/240 (2%) Query: 4 PQPIAAANWKCNGSQQSLSELIDLFNS-TSINHDVQCVVASTFVHLAMTKERLS--HPKF 60 P+ NWK NGS++ + +L++ N+ V VA + + + + L+ Sbjct: 2 RHPVVMGNWKLNGSKEMVVDLLNGLNAELEGVTGVDVAVAPPALFVDLAERTLTEAGSAI 61 Query: 61 VIAAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 ++ AQN SGAFTG++S +LK+FG I++GHSERR Y+ E++E VA K A + Sbjct: 62 ILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHAESDEFVAKKFAFLKEN 121 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G + CIGE+ + E+G T V Q+ A+ +IAYEP+WAIGTGK AT Sbjct: 122 GLTPVLCIGESDAQNEAGETMAVCARQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAAT 181 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 + AQ HA IR+ ++ K VA + I YGGSV +NA + Q D++G LVGGA+L Sbjct: 182 AEDAQRIHAQIRAHIAEK-SEAVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAALD 240 >4G1K-A nrPDB Length = 272 Score = 295 bits (757), Expect = 8e-81, Method: Composition-based stats. Identities = 105/255 (41%), Positives = 154/255 (60%), Gaps = 9/255 (3%) Query: 1 MSKPQ-PIAAANWKCNGSQQSLSELIDLFNSTS--INHDVQCVVASTFVHLAMTKERLSH 57 MSK + NWK +G L+ + ++ +V V F +LA + +L Sbjct: 22 MSKQRIKRVIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQG 81 Query: 58 PKFVIAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAA 116 + +Q+ A + GA+TGEV+ ++ +FG + ++GHSERRAY+GE+NE VA K A Sbjct: 82 GRVSWGSQDVSAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRA 141 Query: 117 VASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGK 176 +A+G I C+GETL ERE+G T VV Q+ A+ L + A++V+AYEPVWAIGTGK Sbjct: 142 LAAGLTPIVCVGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGK 201 Query: 177 VATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGA 236 AT +QAQ+ HA +R ++ A AG + +LYGGSV NA L+ Q D++G L+GGA Sbjct: 202 SATAEQAQQVHAFLRGRLA----AKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGA 257 Query: 237 SLK-PEFVDIIKATQ 250 SLK +F+ I +A + Sbjct: 258 SLKSGDFLAICRAAK 272 >3TA6-A nrPDB Length = 267 Score = 295 bits (755), Expect = 1e-80, Method: Composition-based stats. Identities = 95/245 (38%), Positives = 127/245 (51%), Gaps = 6/245 (2%) Query: 3 KPQPIAAANWKCNGSQQSLSELIDLFNSTSIN---HDVQCVVASTFVHLAMTKERLSHPK 59 +P+ A NWK N + L+ + + V V F L + + K Sbjct: 2 SRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDGDK 61 Query: 60 FVI--AAQNAI-AKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAA 116 + AQ+ SGA+TG+VS L G +++V+GHSERR Y+ E + +VA K A A Sbjct: 62 LRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAATA 121 Query: 117 VASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGK 176 + G I CIGE L RE+G + Q+ L VVIAYEPVWAIGTG+ Sbjct: 122 LKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGTGR 181 Query: 177 VATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGA 236 VA+ AQE A IR ++S +A +R+LYGGSVN KN + Q DV+G LVGGA Sbjct: 182 VASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGGA 241 Query: 237 SLKPE 241 SL E Sbjct: 242 SLDGE 246 >4Y90-A nrPDB Length = 247 Score = 269 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 97/252 (38%), Positives = 136/252 (53%), Gaps = 9/252 (3%) Query: 2 SKPQPIAAANWKCNGSQQSL-SELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKF 60 S Q + A NWK N + S +L + V V + + L+ L Sbjct: 2 SHMQTLLALNWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPALDLSALAANLP-AGI 60 Query: 61 VIAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVAS 119 Q+ A +SGA+TGE+S +LKD G + +V+GHSERR Y+ E++ VA K A A+ Sbjct: 61 AFGGQDVSAHESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDATVAAKARQAQAN 120 Query: 120 GFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 179 G + I C+GE L RE G L Q+ + + A VV+AYEPVWAIGTGK AT Sbjct: 121 GLLPIVCVGENLDVRERGEHVPQTLAQLRGSLEGVG----ADVVVAYEPVWAIGTGKTAT 176 Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLK 239 A+E A IR + + GA A +R+LYGGSV +N + + +VNG LVGGASLK Sbjct: 177 ADDAEELAAAIRGALREQYGAR-AEGIRVLYGGSVKPENIAEICGKPNVNGALVGGASLK 235 Query: 240 -PEFVDIIKATQ 250 P+ + ++ A + Sbjct: 236 VPDVLGMLDALR 247 >2JGQ-A nrPDB Length = 233 Score = 208 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 120/254 (47%), Gaps = 38/254 (14%) Query: 6 PIAAANWK----CNGSQQSLSELIDLFNS-----TSINHDVQCVVASTFVHLAMTKERLS 56 IA AN+K S L EL + D ++ ++F+H Sbjct: 2 KIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDRVFVFPDFFGLLPNSFLH--------- 52 Query: 57 HPKFVIAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAA 115 F + QNA + GAFTGE++ L++ ++ +++GHSERR E+ + +K Sbjct: 53 ---FTLGVQNAYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRTLLKESPSFLKEKFDF 109 Query: 116 AVASGFMVIACIGETLQERESGRTA--VVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIG 173 + F ++ CIGE L RE G A + Q+ I ++ +V+AYEP+WAIG Sbjct: 110 FKSKNFKIVYCIGEELTTREKGFKAVKEFLSEQLENI-----DLNYPNLVVAYEPIWAIG 164 Query: 174 TGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLV 233 T K A+ + H ++ ++ K +LYGGSVN +NA+ + V+G L+ Sbjct: 165 TKKSASLEDIYLTHGFLKQILNQK--------TPLLYGGSVNTQNAKEILGIDSVDGLLI 216 Query: 234 GGASLKPE-FVDII 246 G AS + E F II Sbjct: 217 GSASWELENFKTII 230 >3S6D-A nrPDB Length = 310 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 72/199 (36%), Positives = 103/199 (51%), Gaps = 19/199 (9%) Query: 47 HLAMTKERLSHPKFVIAAQNAIAKS-GAFTGEVSLPILKDFGVNWIVLGHSERRAYYGET 105 +LA ++ + P ++ AQ+ S G +TGE+S L+D V+ + LGH+ERRA +GET Sbjct: 99 NLAAPQDADTPPPLLLGAQDCFWDSLGPYTGEISPVCLRDMNVSIVELGHAERRAIFGET 158 Query: 106 NEIVADKVAAAVASGFMVIACIGE-----TLQERESGRTAVVVLTQIAAIAKKLKKADWA 160 ++ VA K AAA G + + CIGE + GR QI + + L + A Sbjct: 159 DQQVARKAAAAADQGLIPLVCIGEVSTLGPIVSEAIGRAVGECEAQIRPVLEALPRD--A 216 Query: 161 KVVIAYEPVWAIGTGKVATPQQAQEAH-----ALIRSWVSSKIGADVAGELRILYGGSVN 215 V+ AYEPVWAIG PQ A+ H + IRS V +I GE+RILYGGS Sbjct: 217 PVIFAYEPVWAIG-----KPQPARVDHVGAVVSGIRS-VIERIDRHRKGEVRILYGGSAG 270 Query: 216 GKNARTLYQQRDVNGFLVG 234 ++V+G +G Sbjct: 271 PGLWGPGGLGKEVDGMFLG 289 >5CSS-A nrPDB Length = 226 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 61/154 (39%), Gaps = 31/154 (20%) Query: 32 SINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAKS-GAFTGEVSLPILKDFGVNW 90 + + + + + + L + KF AQ+ A+ GA+TG V + ++ D G+ Sbjct: 30 PVQGKFELIFSPSLLDLEKAAKC---GKFRFFAQHVDAEPYGAYTGHVPMDMMIDLGITG 86 Query: 91 IVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAI 150 +L HSERR + + + + A F ++ C+ E +E + R Sbjct: 87 SILNHSERRL----PRDTIINTLKKASKLDFTIVLCV-ENAEEAKYFR------------ 129 Query: 151 AKKLKKADWAKVVIAYEPVWAIGTGK---VATPQ 181 ++ IAYEP IG A P+ Sbjct: 130 -------EYEPDFIAYEPRDLIGGDVSVSTAKPE 156 >2H6R-A nrPDB Length = 219 Score = 65.3 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 73/215 (33%), Gaps = 42/215 (19%) Query: 23 ELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIA-KSGAFTGEVSLP 81 E+ + S + VA FV L M E + + AQ+ G+ TG + Sbjct: 20 EIAKIAEKVSEESGITIGVAPQFVDLRMIVENV---NIPVYAQHIDNINPGSHTGHILAE 76 Query: 82 ILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGETLQERESGRTAV 141 +KD G ++ HSE+R + ++ G I C T Sbjct: 77 AIKDCGCKGTLINHSEKRMLLADIEAVINK----CKNLGLETIVC------------TNN 120 Query: 142 VVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGAD 201 + ++ A + IA EP IGTG + + +R+ + Sbjct: 121 INTSKAVAAL--------SPDCIAVEPPELIGTGIPVSKANPEVVEGTVRAV------KE 166 Query: 202 VAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGA 236 + ++++L G + + DV L GA Sbjct: 167 INKDVKVLCG--------AGISKGEDVKAALDLGA 193 >1HG3-A nrPDB Length = 225 Score = 64.5 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 45/179 (25%), Positives = 64/179 (35%), Gaps = 31/179 (17%) Query: 1 MSKPQ-PIAAANWK--CNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSH 57 M+K + PI A N+K + + E+ V VVA V L M E + Sbjct: 1 MAKLKEPIIAINFKTYIEATGKRALEIAKAAEKVYKETGVTIVVAPQLVDLRMIAESVEI 60 Query: 58 PKFVIAAQNAIA-KSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAA 116 P + AQ+ K G+ TG V +K+ G +L HSE R + + A Sbjct: 61 P---VFAQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHSENRMILADLEAAI----RRA 113 Query: 117 VASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTG 175 G M + C V +AA+ +A EP IGTG Sbjct: 114 EEVGLMTMVC-----------SNNPAVSAAVAAL---------NPDYVAVEPPELIGTG 152 >1W0M-A nrPDB Length = 226 Score = 60.6 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 51/219 (23%), Positives = 75/219 (34%), Gaps = 40/219 (18%) Query: 4 PQPIAAANWKCNGSQQ--SLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFV 61 PI N+K G EL + V VVA + L + + + P + Sbjct: 2 RLPILIINFKAYGEAAGKRAVELAKAAERAARELGVNIVVAPNHLELGLVSQSVDIPVYA 61 Query: 62 IAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 A + GA T VSL +K+ G + ++L HSE +A VA A + G Sbjct: 62 QGAD--VEAGGAHTAHVSLENIKEAGGSGVILNHSEAPLKLN----DLARLVAKAKSLGL 115 Query: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT-- 179 V+ C + L A +A EP IGTG+ + Sbjct: 116 DVVVCAPDP--------------------RTSLAAAALGPHAVAVEPPELIGTGRAVSRY 155 Query: 180 -PQQAQEAHALIRSWVSS---------KIGADVAGELRI 208 P+ E L+ + G DVA LR+ Sbjct: 156 KPEAIVETVGLVSRHFPEVSVITGAGIESGDDVAAALRL 194 >6OKK-M nrPDB Length = 144 Score = 29.4 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 8/11 (72%), Positives = 10/11 (90%) Query: 166 YEPVWAIGTGK 176 YEP+W IG+GK Sbjct: 50 YEPLWLIGSGK 60 >3KW2-A nrPDB Length = 257 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 4/46 (8%) Query: 83 LKDFGVNWIVL---GHSERRAYYGETNEIVADKV-AAAVASGFMVI 124 L + GV+ +V HSERR E E +A ++ + F VI Sbjct: 99 LVEIGVDEVVFIESEHSERRRIKAERLERIAISAMKQSLKASFPVI 144 >3J1E-A nrPDB Length = 553 Score = 28.7 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 3/67 (4%) Query: 100 AYYGETNEIVADKVAAAVASGFMVIAC---IGETLQERESGRTAVVVLTQIAAIAKKLKK 156 + E ++ +KV +A+G VI C I E Q + + + V + +KL + Sbjct: 274 KFLDEEENLIKEKVDKILATGANVIICQKGIDEVAQSYLAKKGVLAVRRAKKSDLEKLAR 333 Query: 157 ADWAKVV 163 A +VV Sbjct: 334 ATGGRVV 340 >4AF1-A nrPDB Length = 416 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 10/22 (45%), Positives = 16/22 (72%), Gaps = 1/22 (4%) Query: 224 QQRDVNGFLVGGAS-LKPEFVD 244 ++ +++G LVGG S K EF+D Sbjct: 218 KRHEIDGILVGGPSPTKDEFLD 239 >2RUS-A nrPDB Length = 490 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 202 VAGELRILYGG-SVNGKNARTLYQQRDVNGFLVGGASLKP 240 V R L+ G SVN + + +V+G LV G +KP Sbjct: 152 VPEAYRALFDGPSVNISALWKVLGRPEVDGGLVVGTIIKP 191 >4NNP-A nrPDB Length = 291 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 169 VWAIGTGKVATPQQAQEAHALIRSW 193 +W I T K TP+Q ++A ++ Sbjct: 205 IWEINTEKQGTPEQMRQAIEFVKKH 229 >3AGK-A nrPDB Length = 373 Score = 27.9 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 9/60 (15%) Query: 76 GEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGETLQERE 135 GE + + G +L H E+ E + + V A +SG VI + E+L E E Sbjct: 303 GEKDVEAALEMGAVKTLLIH--------ESREDLEEWVEKAKSSGAQVIV-VPESLAEAE 353 >5EMU-A nrPDB Length = 265 Score = 27.9 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 25/58 (43%), Gaps = 11/58 (18%) Query: 174 TGKVA---TPQQAQEAHALIRSW-VSSKIGADVAGELRILYGGSVNGKNARTLYQQRD 227 TGKVA TP+ A+ +IR V +G AG +R ++A+ D Sbjct: 170 TGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVR-------TAEDAQKYLAIAD 220 >1R6V-A nrPDB Length = 671 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 17/110 (15%) Query: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT-PQQAQEA 186 GE L G A+ V Q+ A +++A + TG T P + Sbjct: 128 GEELSNELWGLEAIGVTQQLWEEASG------TNIIVA-----VVDTGVDGTHPDLEGQV 176 Query: 187 HALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGA 236 A R ++ A YGGS A T+ ++D G +VG A Sbjct: 177 IAGYRPAFDEELPAGTDSS----YGGSAGTHVAGTIAAKKDGKG-IVGVA 221 >2VOU-A nrPDB Length = 397 Score = 27.5 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%), Gaps = 8/48 (16%) Query: 182 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVN 229 Q Q+ HA + + V R+ +GGS N + V+ Sbjct: 350 QLQQGHAYL-NKVKKMAS-------RLQHGGSFEPGNPAFAFGLPKVD 389 >3E70-C nrPDB Length = 328 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 34/175 (19%), Positives = 67/175 (38%), Gaps = 26/175 (14%) Query: 16 GSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFT 75 G ++++L + NH V+A++ A E+L I + GA Sbjct: 141 GKTTTIAKLANWLK----NHGFSVVIAASDTFRAGAIEQLEEHAKRIGVKVIKHSYGADP 196 Query: 76 GEVSLPIL---KDFGVNWIVL---GHSE-RRAYYGETNEIVADKVAAAVASGFMVIA--- 125 V+ + K G++ +++ G SE R E K+A ++ Sbjct: 197 AAVAYDAIQHAKARGIDVVLIDTAGRSETNRNLMDE-----MKKIARVTKPNLVIFVGDA 251 Query: 126 ----CIGETLQE-RESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTG 175 I E ++ E+ + ++LT++ A A+ + V+ A P+ +G G Sbjct: 252 LAGNAIVEQARQFNEAVKIDGIILTKLDADARGGAALSISYVIDA--PILFVGVG 304 >4WES-A nrPDB Length = 534 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 12 W-KCN-----GSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQ 65 W KCN G ++L ++ F+ + + V+A +A ++ L + K + + Sbjct: 281 WIKCNFIGVDGIVETLRDMAKCFDDPELTKRTEEVIAE---EIAAIQDDLDYFKEKLQGK 337 Query: 66 NAIAKSGAFTGEVSLPILKDFGVNWIVLG 94 A G + +LK FGV+ +V G Sbjct: 338 TACLYVGGSRSHTYMNMLKSFGVDSLVAG 366 >5FGE-J nrPDB Length = 198 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 19/43 (44%) Query: 184 QEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQR 226 Q + +R ++ I + ++ +L GG KN LYQ Sbjct: 78 QAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 >3WXR-K nrPDB Length = 238 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 19/43 (44%) Query: 184 QEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQR 226 Q + +R ++ I + ++ +L GG KN LYQ Sbjct: 78 QAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 >1RCQ-A nrPDB Length = 357 Score = 27.5 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 28/56 (50%), Gaps = 7/56 (12%) Query: 110 ADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIA 165 + AA A GF +ACI E L+ RE+G + Q + + +A ++++A Sbjct: 44 CAEALAAEADGF-AVACIEEGLELREAG------IRQPILLLEGFFEASELELIVA 92 >2ZXU-A nrPDB Length = 316 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 14/33 (42%) Query: 180 PQQAQEAHALIRSWVSSKIGADVAGELRILYGG 212 P QA A R ++ AG + +L GG Sbjct: 75 PSQAYSAADFRRDALAEMADITAAGRIPLLVGG 107 >5LZY-jj nrPDB Length = 710 Score = 27.1 bits (59), Expect = 6.5, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 31/86 (36%), Gaps = 7/86 (8%) Query: 76 GEVSLPILKDFGVNWIVLGHSERRAYYG-ETNEIVADKVAAAVASGFMVIACIGETLQER 134 G V G +LG+ +R + E A K + A A ET +ER Sbjct: 293 GHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLD------ETGEER 346 Query: 135 ESGRTAVVVLTQIAAIAKKLKKADWA 160 E G T V +T+ K + D Sbjct: 347 ERGVTMDVGMTKFETTTKVITLMDAP 372 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.154 0.491 Lambda K H 0.267 0.0469 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,294,821 Number of Sequences: 36641 Number of extensions: 498922 Number of successful extensions: 1580 Number of sequences better than 10.0: 71 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1298 Number of HSP's gapped (non-prelim): 128 length of query: 250 length of database: 10,336,785 effective HSP length: 95 effective length of query: 155 effective length of database: 6,855,890 effective search space: 1062662950 effective search space used: 1062662950 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.8 bits)