BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04406 (335 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ZNQ-O nrPDB 692 0.0 3GPD-R nrPDB 621 e-178 4K9D-A nrPDB 513 e-146 6DFZ-A nrPDB 507 e-144 1CRW-G nrPDB 502 e-142 3E5R-O nrPDB 489 e-139 2VYN-D nrPDB 486 e-138 3H9E-O nrPDB 481 e-136 5C7I-O nrPDB 480 e-136 4Z0H-O nrPDB 471 e-133 3PYM-A nrPDB 455 e-128 4MVJ-P nrPDB 451 e-127 2B4T-O nrPDB 449 e-127 2I5P-O nrPDB 447 e-126 1VSU-A nrPDB 446 e-126 4P8R-A nrPDB 443 e-125 6NLX-A nrPDB 441 e-124 4LSM-A nrPDB 441 e-124 3STH-A nrPDB 434 e-122 5UR0-A nrPDB 433 e-122 6OK4-A nrPDB 380 e-106 1NPT-O nrPDB 353 4e-98 2X0N-A nrPDB 349 1e-96 1ML3-A nrPDB 341 2e-94 1I33-A nrPDB 332 1e-91 3HJA-A nrPDB 315 2e-86 1HDG-O nrPDB 312 1e-85 2EP7-A nrPDB 304 4e-83 4BOY-A nrPDB 302 1e-82 3GNQ-A nrPDB 301 3e-82 3DOC-A nrPDB 297 4e-81 1OBF-O nrPDB 295 1e-80 3L0D-A nrPDB 295 3e-80 5M6D-A nrPDB 291 2e-79 4DIB-A nrPDB 290 6e-79 5VMT-A nrPDB 287 4e-78 1CER-O nrPDB 284 4e-77 6FZH-A nrPDB 281 3e-76 6FZI-A nrPDB 281 3e-76 1VC2-A nrPDB 278 2e-75 5JY6-A nrPDB 278 3e-75 3VAZ-P nrPDB 277 5e-75 3B1K-A nrPDB 276 8e-75 2DUU-A nrPDB 276 1e-74 2PKQ-O nrPDB 275 2e-74 1JN0-O nrPDB 272 1e-73 3RVD-A nrPDB 256 1e-68 2XF8-A nrPDB 251 4e-67 6IQV-A nrPDB 244 5e-65 5LD5-A nrPDB 244 5e-65 5J9G-A nrPDB 230 8e-61 3TZ6-A nrPDB 45 5e-05 2YV3-A nrPDB 38 0.005 2CZC-A nrPDB 33 0.15 3HSK-A nrPDB 32 0.27 3SDS-A nrPDB 31 0.67 1BSF-A nrPDB 31 0.74 1YS4-A nrPDB 31 0.78 3L2D-A nrPDB 31 0.91 1IPK-A nrPDB 30 1.5 1C8B-A nrPDB 30 2.1 3LS0-A nrPDB 29 3.0 5W64-O nrPDB 28 4.8 5N61-P nrPDB 28 5.0 2YYY-A nrPDB 28 5.0 3WYB-A nrPDB 28 5.3 5W65-O nrPDB 28 5.4 2IV0-A nrPDB 28 5.6 4KKJ-A nrPDB 28 6.5 2R00-A nrPDB 28 6.7 4FCY-A nrPDB 27 8.8 >1ZNQ-O nrPDB Length = 338 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV Sbjct: 4 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 63 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI Sbjct: 64 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 123 Query: 121 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA Sbjct: 124 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 183 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV Sbjct: 184 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 243 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG Sbjct: 244 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 303 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE Sbjct: 304 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 338 >3GPD-R nrPDB Length = 334 Score = 621 bits (1601), Expect = e-178, Method: Compositional matrix adjust. Identities = 300/334 (89%), Positives = 314/334 (94%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 GKVKVGV+GFGRIGRLVTRAAFNSGKVDIVAINDPFIDL+YMVYMFQYDSTHGKFHGTVK Sbjct: 1 GKVKVGVDGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLHYMVYMFQYDSTHGKFHGTVK 60 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 AE+GKLVI+G ITIFQERDP IKWGDAG YVVESTGVFTTMEKAGAHL+GGAKR++I Sbjct: 61 AEDGKLVIDGKAITIFQERDPENIKWGDAGTAYVVESTGVFTTMEKAGAHLKGGAKRIVI 120 Query: 122 SAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 SAPSADAPMFVMGVNH KY NSLKIISNASCTTNCLAPLAKVIHD+FGIVEGLMTTVHAI Sbjct: 121 SAPSADAPMFVMGVNHFKYANSLKIISNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAI 180 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQKTVD PSGKLWR GRGA QN+IPASTGAAKAVGKVIPEL+GKLTGMAFRVPTANVS Sbjct: 181 TATQKTVDSPSGKLWRGGRGAAQNLIPASTGAAKAVGKVIPELDGKLTGMAFRVPTANVS 240 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 V+DLTCRLEKPAKYDDIKKVVK+ASEGPLKGILGYTE +VVS DFN HSS FDAGAGI Sbjct: 241 VLDLTCRLEKPAKYDDIKKVVKEASEGPLKGILGYTEDEVVSDDFNGSNHSSIFDAGAGI 300 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 LND FVKL+SWYDNEFGYS RVVDLMAHMASKE Sbjct: 301 ELNDTFVKLVSWYDNEFGYSERVVDLMAHMASKE 334 >4K9D-A nrPDB Length = 347 Score = 513 bits (1321), Expect = e-146, Method: Compositional matrix adjust. Identities = 251/339 (74%), Positives = 291/339 (85%), Gaps = 5/339 (1%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 M K KVG+NGFGRIGRLV RAA VD+VA+NDPFI+++YMVYMF+YDSTHG+F G+V Sbjct: 9 MSKPKVGINGFGRIGRLVLRAAVEKDTVDVVAVNDPFINIDYMVYMFKYDSTHGRFKGSV 68 Query: 61 KAENGKLVI-NGNP---ITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGA 116 AE GKL++ NG I++ +DP++I WG GAEYVVESTGVFTT +KA AHL+GGA Sbjct: 69 SAEGGKLIVTNGKTTHHISVHNSKDPAEIPWGVDGAEYVVESTGVFTTTDKASAHLKGGA 128 Query: 117 KRVIISAPSADAPMFVMGVNHEKYDNSLK-IISNASCTTNCLAPLAKVIHDNFGIVEGLM 175 K+VIISAPSADAPMFVMGVN++ YD + IISNASCTTNCLAPLAKVIHD FGI+EGLM Sbjct: 129 KKVIISAPSADAPMFVMGVNNDTYDKANNHIISNASCTTNCLAPLAKVIHDKFGIIEGLM 188 Query: 176 TTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRV 235 TTVHA TATQKTVDGPSGKLWRDGRGA QNIIPASTGAAKAVGKVIP+LNGKLTGMAFRV Sbjct: 189 TTVHATTATQKTVDGPSGKLWRDGRGAGQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRV 248 Query: 236 PTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTF 295 PT +VSVVDLTCRL+K A D+IK VK+A+ GP+KGIL YTE QVVS+DF DTHSS F Sbjct: 249 PTPDVSVVDLTCRLQKGATMDEIKAAVKEAANGPMKGILEYTEDQVVSTDFTGDTHSSIF 308 Query: 296 DAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 DA A I+LN +FVKLI+WYDNE+GYSNRVVDL++++AS+ Sbjct: 309 DALACISLNPNFVKLIAWYDNEYGYSNRVVDLISYIASR 347 >6DFZ-A nrPDB Length = 332 Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust. Identities = 249/332 (75%), Positives = 288/332 (86%), Gaps = 1/332 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRLV RA+ +V +VA+NDPFIDL YM YMF+YDSTHG+F GT + + Sbjct: 1 VKVGINGFGRIGRLVMRASLEHPEVQVVAVNDPFIDLEYMEYMFKYDSTHGRFKGTTEVK 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +GKLVINGNPI+++ +DP+ I W +AGA++VVESTGVFTT EKA AHL GGAK+VIISA Sbjct: 61 DGKLVINGNPISVYALKDPAAIPWKEAGADFVVESTGVFTTTEKASAHLHGGAKKVIISA 120 Query: 124 PSADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PSADAPMFVMGVN + YD ++ ++SNASCTTNCLAPLAKVI+DNFGI EGLMTT+HA T Sbjct: 121 PSADAPMFVMGVNEKTYDAATMNVVSNASCTTNCLAPLAKVINDNFGIEEGLMTTIHAYT 180 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPSGK WRDGRGA QN+IPA+TGAAKAVGKVIPELNGKLTGMAFRVP +VSV Sbjct: 181 ATQKTVDGPSGKKWRDGRGANQNVIPATTGAAKAVGKVIPELNGKLTGMAFRVPVPDVSV 240 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLTCRL+KP Y++IKKVVK+ASE LKG L YTE QVVSSDF SDTHSS FDA AGI Sbjct: 241 VDLTCRLKKPTSYEEIKKVVKKASETDLKGFLAYTEDQVVSSDFISDTHSSVFDALAGIQ 300 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 LN FVKL+SWYDNE+GYS+RVVDL+ +MA+K Sbjct: 301 LNPTFVKLVSWYDNEYGYSHRVVDLIEYMATK 332 >1CRW-G nrPDB Length = 333 Score = 502 bits (1292), Expect = e-142, Method: Compositional matrix adjust. Identities = 239/327 (73%), Positives = 269/327 (82%), Gaps = 1/327 (0%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 K+G+NGFGRIGRLV RAA G +VA+NDPFI L YMVYMF+YDSTHG F G VKAE+ Sbjct: 2 KIGINGFGRIGRLVLRAALEMG-AQVVAVNDPFIALEYMVYMFKYDSTHGMFKGEVKAED 60 Query: 65 GKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAP 124 G LV++G IT+F E P I W AGAEY+VESTGVFTT+EKA AH +GGAK+VIISAP Sbjct: 61 GALVVDGKKITVFNEMKPENIPWSKAGAEYIVESTGVFTTIEKASAHFKGGAKKVIISAP 120 Query: 125 SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITAT 184 SADAPMFV GVN EKY +K++SNASCTTNCLAP+AKV+H+NF IVEGLMTTVHA+TAT Sbjct: 121 SADAPMFVCGVNLEKYSKDMKVVSNASCTTNCLAPVAKVLHENFEIVEGLMTTVHAVTAT 180 Query: 185 QKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVD 244 QKTVDGPS K WR GRGA QNIIP+STGAAKAVGKVIPEL+GKLTGMAFRVPT NVSVVD Sbjct: 181 QKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPELDGKLTGMAFRVPTPNVSVVD 240 Query: 245 LTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALN 304 LT RL K YDDIK +K ASEGPL+G+LGYTE VVS DF D SS FDA AGI L+ Sbjct: 241 LTVRLGKECSYDDIKAAMKAASEGPLQGVLGYTEDDVVSCDFTGDNRSSIFDAKAGIQLS 300 Query: 305 DHFVKLISWYDNEFGYSNRVVDLMAHM 331 FVK++SWYDNEFGYS RV+DL+ HM Sbjct: 301 KTFVKVVSWYDNEFGYSQRVIDLIKHM 327 >3E5R-O nrPDB Length = 337 Score = 489 bits (1259), Expect = e-139, Method: Compositional matrix adjust. Identities = 231/337 (68%), Positives = 278/337 (82%), Gaps = 2/337 (0%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKF-HGT 59 MGK+K+G+NGFGRIGRLV R A S V++VA+NDPFI +YM YMF+YD+ HG++ H Sbjct: 1 MGKIKIGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQWKHSD 60 Query: 60 VKAENGK-LVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKR 118 +K ++ K L++ P+T+F R+P +I W +AGAEYVVESTGVFT EKA AHL+GGAK+ Sbjct: 61 IKIKDSKTLLLGEKPVTVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKAAAHLKGGAKK 120 Query: 119 VIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 V+ISAPS DAPMFV GVN +KY + + I+SNASCTTNCLAPLAKVIHDNFGI+EGLMTTV Sbjct: 121 VVISAPSKDAPMFVCGVNEDKYTSDIDIVSNASCTTNCLAPLAKVIHDNFGIIEGLMTTV 180 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 HAITATQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+P+LNGKLTGM+FRVPT Sbjct: 181 HAITATQKTVDGPSSKDWRGGRAASFNIIPSSTGAAKAVGKVLPDLNGKLTGMSFRVPTV 240 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 +VSVVDLT R+EK A YD IK +K ASEG LKGI+GY E +VS+DF D+ SS FDA Sbjct: 241 DVSVVDLTVRIEKAASYDAIKSAIKSASEGKLKGIIGYVEEDLVSTDFVGDSRSSIFDAK 300 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 AGIALND+FVKL++WYDNE+GYSNRV+DL+ HMA + Sbjct: 301 AGIALNDNFVKLVAWYDNEWGYSNRVIDLIRHMAKTQ 337 >2VYN-D nrPDB Length = 334 Score = 486 bits (1252), Expect = e-138, Method: Compositional matrix adjust. Identities = 231/333 (69%), Positives = 275/333 (82%), Gaps = 2/333 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRLV R G V +VA+NDPFID YMVYMF+YDSTHG++ GTV+ + Sbjct: 2 VKVGINGFGRIGRLVLRVCMEKG-VRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGTVEHK 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 NG+LV++ I +FQ ++P +I W G YVVE+TGV+ ++E A H+ GA+RVI++A Sbjct: 61 NGRLVVDNLEINVFQCKEPKEIPWSSVGNPYVVEATGVYLSIEAASGHISSGARRVIVTA 120 Query: 124 PSADAPMFVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PS DAPM VMGVN + Y+ S+ ++SNASCTTNCLAPLAKVIH+ FGIVEGLMTTVHA T Sbjct: 121 PSPDAPMLVMGVNEKDYNPGSMTVVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHAYT 180 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGKVIPELNGKLTGMAFRVPT NVSV Sbjct: 181 ATQKTVDGPSKKDWRGGRGAHQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV 240 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLTCRL +PA Y IK+ VK A++GP+ GIL YTE QVVS+DFN D+HSS FDA AGIA Sbjct: 241 VDLTCRLAQPASYTAIKEAVKAAAKGPMAGILAYTEDQVVSTDFNGDSHSSIFDAKAGIA 300 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 LND+FVKL+SWYDNE+GYS+RVVDL+ +M S+E Sbjct: 301 LNDNFVKLVSWYDNEYGYSHRVVDLLRYMFSRE 333 >3H9E-O nrPDB Length = 346 Score = 481 bits (1237), Expect = e-136, Method: Compositional matrix adjust. Identities = 228/334 (68%), Positives = 276/334 (82%), Gaps = 2/334 (0%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 ++ VG+NGFGRIGRLV RA G V +VA+NDPFID YMVYMF+YDSTHG++ G+V+ Sbjct: 7 ELTVGINGFGRIGRLVLRACMEKG-VKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEF 65 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 NG+LV++ + I+++Q ++P +I W G+ YVVESTGV+ +++ A H+ GA+RV+IS Sbjct: 66 RNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVIS 125 Query: 123 APSADAPMFVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 APS DAPMFVMGVN Y+ S+ I+SNASCTTNCLAPLAKVIH+ FGIVEGLMTTVH+ Sbjct: 126 APSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSY 185 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQKTVDGPS K WRDGRGA QNIIPASTGAAKAV KVIPEL GKLTGMAFRVPT +VS Sbjct: 186 TATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVS 245 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLTCRL +PA Y IK+ VK A++GP+ GIL YTE +VVS+DF DTHSS FDA AGI Sbjct: 246 VVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGI 305 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 ALND+FVKLISWYDNE+GYS+RVVDL+ +M S++ Sbjct: 306 ALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRD 339 >5C7I-O nrPDB Length = 333 Score = 480 bits (1236), Expect = e-136, Method: Compositional matrix adjust. Identities = 228/334 (68%), Positives = 272/334 (81%), Gaps = 2/334 (0%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 ++ VG+NGFGRIGRLV R G + +VA+NDPFID YMVYMF+YDSTHG++ G V+ Sbjct: 1 ELTVGINGFGRIGRLVLRVCMEKG-IRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGNVEH 59 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 +NG+LV++ I +Q +DP +I W G YVVE TGV+ ++E A AH+ GA+RV+++ Sbjct: 60 KNGQLVVDNLEINTYQCKDPKEIPWSSIGNPYVVECTGVYLSIEAASAHISSGARRVVVT 119 Query: 123 APSADAPMFVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 APS DAPMFVMGVN + Y+ S+ I+SNASCTTNCLAPLAKVIH+NFGIVEGLMTTVH+ Sbjct: 120 APSPDAPMFVMGVNEKDYNPGSMTIVSNASCTTNCLAPLAKVIHENFGIVEGLMTTVHSY 179 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGKVIPEL GKLTGMAFRVPT NVS Sbjct: 180 TATQKTVDGPSKKDWRGGRGAHQNIIPSSTGAAKAVGKVIPELKGKLTGMAFRVPTPNVS 239 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLTCRL KPA Y I + VK A++GPL GIL YTE QVVS+DFN + HSS FDA AGI Sbjct: 240 VVDLTCRLAKPASYSAITEAVKAAAKGPLAGILAYTEDQVVSTDFNGNPHSSIFDAKAGI 299 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 ALND+FVKL++WYDNE+GYSNRVVDL+ +M S+E Sbjct: 300 ALNDNFVKLVAWYDNEYGYSNRVVDLLRYMFSRE 333 >4Z0H-O nrPDB Length = 334 Score = 471 bits (1211), Expect = e-133, Method: Compositional matrix adjust. Identities = 226/332 (68%), Positives = 270/332 (81%), Gaps = 2/332 (0%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKF-HGTVK 61 K+++G+NGFGRIGRLV R V++VA+NDPFI YM YMF+YDS HG++ H +K Sbjct: 1 KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELK 60 Query: 62 AENGKLVINGN-PITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 ++ K ++ G P+T+F R+P I W +AGA+YVVESTGVFT +KA AHL+GGAK+V+ Sbjct: 61 IKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVV 120 Query: 121 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 ISAPS DAPMFV+GVN +Y + L I+SNASCTTNCLAPLAKVI+D FGIVEGLMTTVH+ Sbjct: 121 ISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHS 180 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 ITATQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+P LNGKLTGM+FRVPT +V Sbjct: 181 ITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDV 240 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLT RLEK A YD+IKK +K+ SEG LKGILGYTE VVS+DF D SS FDA AG Sbjct: 241 SVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAG 300 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 IAL+D FVKL+SWYDNE+GYS+RVVDL+ HM+ Sbjct: 301 IALSDKFVKLVSWYDNEWGYSSRVVDLIVHMS 332 >3PYM-A nrPDB Length = 332 Score = 455 bits (1171), Expect = e-128, Method: Compositional matrix adjust. Identities = 214/329 (65%), Positives = 262/329 (79%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 V+V +NGFGRIGRLV R A + V++VA+NDPFI +Y YMF+YDSTHG++ G V + Sbjct: 2 VRVAINGFGRIGRLVMRIALSRPNVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHD 61 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + ++++G I +QERDP+ + WG + + ++STGVF ++ A H+ GAK+V+I+A Sbjct: 62 DKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITA 121 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 PS+ APMFVMGVN EKY + LKI+SNASCTTNCLAPLAKVI+D FGI EGLMTTVH++TA Sbjct: 122 PSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTA 181 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+PEL GKLTGMAFRVPT +VSVV Sbjct: 182 TQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVV 241 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIAL 303 DLT +L K YD+IKKVVK A+EG LKG+LGYTE VVSSDF D+HSS FDA AGI L Sbjct: 242 DLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQL 301 Query: 304 NDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 + FVKL+SWYDNE+GYS RVVDL+ H+A Sbjct: 302 SPKFVKLVSWYDNEYGYSTRVVDLVEHVA 330 >4MVJ-P nrPDB Length = 355 Score = 451 bits (1161), Expect = e-127, Method: Compositional matrix adjust. Identities = 218/330 (66%), Positives = 264/330 (80%), Gaps = 3/330 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR+V RAA ++IVAIND +D +YM YM +YDSTHG+F GTV+ + Sbjct: 27 IKVGINGFGRIGRIVFRAAQKRSDIEIVAIND-LLDADYMAYMLKYDSTHGRFDGTVEVK 85 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +G L++NG I + ERDP+ +KW + G + V E+TG+F T E A H+ GAK+V+++ Sbjct: 86 DGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTG 145 Query: 124 PSAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PS D PMFV G N +KY I+SNASCTTNCLAPLAKVI+DNFGI+EGLMTTVHA T Sbjct: 146 PSKDNTPMFVKGANFDKYAGQ-DIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATT 204 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGKV+PELNGKLTGMAFRVPT NVSV Sbjct: 205 ATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSV 264 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLT RLEK A Y+ IK VK A+EG +KG+LGYTE VVS+DFN + +S FDA AGIA Sbjct: 265 VDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIA 324 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 LND+FVKL+SWYDNE GYSN+V+DL+AH++ Sbjct: 325 LNDNFVKLVSWYDNETGYSNKVLDLIAHIS 354 >2B4T-O nrPDB Length = 345 Score = 449 bits (1156), Expect = e-127, Method: Compositional matrix adjust. Identities = 215/332 (64%), Positives = 261/332 (78%), Gaps = 3/332 (0%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 K+G+NGFGRIGRLV RAAF +++VAINDPF+DLN++ Y+ +YDS HG+F V + Sbjct: 13 KLGINGFGRIGRLVFRAAFGRKDIEVVAINDPFMDLNHLCYLLKYDSVHGQFPCEVTHAD 72 Query: 65 GKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAP 124 G L+I +++F E+DPS+I WG + V ESTGVF T E A +HL+GGAK+VI+SAP Sbjct: 73 GFLLIGEKKVSVFAEKDPSQIPWGKCQVDVVCESTGVFLTKELASSHLKGGAKKVIMSAP 132 Query: 125 SAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 D P++VMG+NH +YD I+SNASCTTNCLAPLAKVI+D FGIVEGLMTTVHA TA Sbjct: 133 PKDDTPIYVMGINHHQYDTKQLIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHASTA 192 Query: 184 TQKTVDGPS--GKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q VDGPS GK WR GR AL NIIPASTGAAKAVGKV+PELNGKLTG+AFRVP VS Sbjct: 193 NQLVVDGPSKGGKDWRAGRCALSNIIPASTGAAKAVGKVLPELNGKLTGVAFRVPIGTVS 252 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDL CRL+KPAKY+++ +K+A+EGPLKGILGYTE +VVS DF D SS FD AG+ Sbjct: 253 VVDLVCRLQKPAKYEEVALEIKKAAEGPLKGILGYTEDEVVSQDFVHDNRSSIFDMKAGL 312 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 ALND+F KL+SWYDNE+GYSNRV+DL H+ + Sbjct: 313 ALNDNFFKLVSWYDNEWGYSNRVLDLAVHITT 344 >2I5P-O nrPDB Length = 342 Score = 447 bits (1151), Expect = e-126, Method: Compositional matrix adjust. Identities = 212/329 (64%), Positives = 257/329 (78%), Gaps = 1/329 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 V + +NGFGRIGRLV R A +D+VAINDPFI ++Y YMF+YDSTHGK+ G V + Sbjct: 15 VSIAINGFGRIGRLVLRIALERKNIDVVAINDPFISVDYAAYMFKYDSTHGKYKGEVSHD 74 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 L+ING + +FQE+DP+ + WG G + V+STGVF ++ A H+ GAK+V+I+A Sbjct: 75 GSNLIINGKKVAVFQEKDPATLPWGKLGVDIAVDSTGVFKELDSAQKHIDAGAKKVVITA 134 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 PS APMFV+GVN +KY N KI+SNASCTTNCLAP+AK+I+D FGI EGLMTTVH+ITA Sbjct: 135 PSKTAPMFVVGVNEDKY-NGEKIVSNASCTTNCLAPIAKIINDEFGIEEGLMTTVHSITA 193 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+PEL GKLTGMAFRVPT +VSVV Sbjct: 194 TQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTTDVSVV 253 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIAL 303 DLT +L K A YD+IK VK+ SEG LK ++GYTE VVSSDF DTHS+ FDA AGI L Sbjct: 254 DLTVKLVKAATYDEIKAAVKKVSEGKLKDVVGYTEDAVVSSDFLGDTHSTIFDAAAGIQL 313 Query: 304 NDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 + FVKL++WYDNE+GYS RVVDL+ H+A Sbjct: 314 SPKFVKLVAWYDNEYGYSTRVVDLVEHVA 342 >1VSU-A nrPDB Length = 359 Score = 446 bits (1147), Expect = e-126, Method: Compositional matrix adjust. Identities = 219/333 (65%), Positives = 260/333 (78%), Gaps = 4/333 (1%) Query: 6 VGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENG 65 +G+NGFGRIGRLV RA + +VAINDPF+D+ YM Y+ +YDS HG F+GTV+ Sbjct: 25 LGINGFGRIGRLVLRACMERNDITVVAINDPFMDVEYMAYLLKYDSVHGNFNGTVEVSGK 84 Query: 66 KLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPS 125 L ING + +FQ +DP++I WG +GA+ V ESTGVFTT EKA HL+GGAK+VIISAP Sbjct: 85 DLCINGKVVKVFQAKDPAEIPWGASGAQIVCESTGVFTTEEKASLHLKGGAKKVIISAPP 144 Query: 126 AD-APMFVMGVNHEKYDNS-LKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 D PM+VMGVN+ +YD S +ISNASCTTNCLAPLAK+I+D FGIVEGLMTTVH++TA Sbjct: 145 KDNVPMYVMGVNNTEYDPSKFNVISNASCTTNCLAPLAKIINDKFGIVEGLMTTVHSLTA 204 Query: 184 TQKTVDGPS--GKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q TVDGPS GK WR GR A NIIPASTGAAKAVGKVIP LNGKLTGMA RVPT +VS Sbjct: 205 NQLTVDGPSKGGKDWRAGRCAGNNIIPASTGAAKAVGKVIPALNGKLTGMAIRVPTPDVS 264 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLTC+L KPA ++I + VK+AS GP+KGI+GYT VVS+DF +SS FD A I Sbjct: 265 VVDLTCKLAKPASIEEIYQAVKEASNGPMKGIMGYTSDDVVSTDFIGCKYSSIFDKNACI 324 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 ALND FVKLISWYDNE GYSNR+VDL ++AS+ Sbjct: 325 ALNDSFVKLISWYDNESGYSNRLVDLAVYVASR 357 >4P8R-A nrPDB Length = 339 Score = 443 bits (1139), Expect = e-125, Method: Compositional matrix adjust. Identities = 214/329 (65%), Positives = 257/329 (78%), Gaps = 3/329 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 ++VG+NGFGRIGR+V RAA ++IV IND +D +YM YM +YDSTHG+F G V+ + Sbjct: 11 IRVGINGFGRIGRVVFRAAQRRNDIEIVGIND-LLDADYMAYMLKYDSTHGRFEGAVEVQ 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 G LV+NG I + ERDP+ +KW + + VVESTG+F + + A H+Q GAK+V+I+ Sbjct: 70 GGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITG 129 Query: 124 PSAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PS D PMFVMGVNH Y I+SNASCTTNCLAPLAKV++D FGIVEGLMTTVHA T Sbjct: 130 PSKDDTPMFVMGVNHTTYKGE-AIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATT 188 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGK+IP LNGKLTGMAFRVPT NVSV Sbjct: 189 ATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSV 248 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLT RLE+PA Y I +K ASEG LKGILGY + ++VSSD N +S FDA AGI+ Sbjct: 249 VDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGIS 308 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHM 331 LND+FVKL+SWYDNE GYSN+V+DL+AH+ Sbjct: 309 LNDNFVKLVSWYDNETGYSNKVLDLIAHI 337 >6NLX-A nrPDB Length = 341 Score = 441 bits (1135), Expect = e-124, Method: Compositional matrix adjust. Identities = 212/326 (65%), Positives = 258/326 (79%), Gaps = 2/326 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRLV RA+ V++VAIND + +YM+YM +YDS HGKF+G ++ Sbjct: 10 VKVGINGFGRIGRLVFRASLERTDVEVVAINDIMMTPDYMIYMIKYDSVHGKFNGKLEYT 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + +NG I +F ER+P K+ WG G EYVVESTGVFT ++ A HL+GGAKRV+ISA Sbjct: 70 ENSIKVNGREIHVFCEREPEKLPWGQYGVEYVVESTGVFTKLDTASKHLKGGAKRVVISA 129 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 P AD P FVMGVN+ ++ + +I+NASCTTNCLAP+A V+H+NFGIVEGLMTTVHA+TA Sbjct: 130 P-ADTPTFVMGVNNHEFKPEMTVINNASCTTNCLAPIAAVLHENFGIVEGLMTTVHALTA 188 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQ TVD PS K WR GR A NIIP+STGAAKAVG VIP LNGKLTGMAFRVPTA+VSVV Sbjct: 189 TQPTVDAPSKKDWRGGRAAGYNIIPSSTGAAKAVGLVIPSLNGKLTGMAFRVPTADVSVV 248 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGP-LKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 DLTCRLEKPA I + +K+ASE KGIL YTE +VVSSDF D+ SST+D+ A I+ Sbjct: 249 DLTCRLEKPATKKQIDEAMKKASESERFKGILKYTEEEVVSSDFIHDSASSTYDSKASIS 308 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLM 328 LNDHFVK+++WYDNE+GYSNRV+DL+ Sbjct: 309 LNDHFVKVVAWYDNEWGYSNRVLDLI 334 >4LSM-A nrPDB Length = 346 Score = 441 bits (1133), Expect = e-124, Method: Compositional matrix adjust. Identities = 213/331 (64%), Positives = 260/331 (78%), Gaps = 3/331 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +K+G+NGFGRIGR+V RAA + ++IV IND +D +YM YM +YDSTHG++ G V+ Sbjct: 17 IKIGINGFGRIGRMVFRAAQHRNDIEIVGIND-LLDADYMAYMLKYDSTHGRYGGMVEVR 75 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 G LV+NG I + ERDP+ +KW + GA VVESTG+F T E A H+Q GAK+V+++ Sbjct: 76 EGALVVNGKKIRVTSERDPANLKWNEVGAVVVVESTGLFLTDETARKHIQAGAKKVVMTG 135 Query: 124 PSAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P D PMFVMGVN+ Y +I+SNASCTTNCLAPLAK+IH+ FGIVEGLMTTVHA T Sbjct: 136 PPKDDTPMFVMGVNNTMYKGQ-EIVSNASCTTNCLAPLAKIIHEKFGIVEGLMTTVHATT 194 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP++TGAAKAVGKVIP LNG+LTGMAFRVPT NVSV Sbjct: 195 ATQKTVDGPSQKDWRGGRGAAQNIIPSATGAAKAVGKVIPALNGRLTGMAFRVPTPNVSV 254 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLT RLE+PA Y+ I +K ASEG LKGILGYTE +VVS+D N +S FD AGI+ Sbjct: 255 VDLTARLERPATYEQICAAIKAASEGELKGILGYTEDEVVSTDMNGVALTSVFDVKAGIS 314 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 LND FVKLISWYDNE GYS++V+DL+A++++ Sbjct: 315 LNDRFVKLISWYDNETGYSHKVLDLVAYISA 345 >3STH-A nrPDB Length = 361 Score = 434 bits (1115), Expect = e-122, Method: Compositional matrix adjust. Identities = 217/336 (64%), Positives = 266/336 (79%), Gaps = 4/336 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 K+G+NGFGRIGRLV RAA G V+++AINDPF+ L+YMVY+ +YDS HG + G V + Sbjct: 24 CKLGINGFGRIGRLVFRAAMERGDVEVLAINDPFMSLDYMVYLLRYDSVHGHYPGEVSHK 83 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +GKL++ G +T+F E++P+ I WG AG Y+ ESTG+F T EKA AHL GAK+VI+SA Sbjct: 84 DGKLIVGGKAVTVFNEKEPTAIPWGQAGVHYICESTGIFLTKEKAQAHLTNGAKKVIMSA 143 Query: 124 PSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P D PMFVMGVN+++Y +S I+SNASCTTNCLAPLAK++HD FGIVEGLMTTVHA+T Sbjct: 144 PPKDDTPMFVMGVNNDQYKSSDVIVSNASCTTNCLAPLAKIVHDKFGIVEGLMTTVHAMT 203 Query: 183 ATQKTVDGPS--GKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 A Q TVDGPS GK WR GR A NIIPASTGAAKAVGK+IP LNGKLTGMAFRVP +V Sbjct: 204 ANQLTVDGPSKGGKDWRAGRSAGVNIIPASTGAAKAVGKIIPSLNGKLTGMAFRVPVPDV 263 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQ-ASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGA 299 SVVDLTC+L KPAKY+DI VK+ A+ GP+KGI+ YT+ +VVSSDF SS FD A Sbjct: 264 SVVDLTCKLAKPAKYEDIVAAVKEAATSGPMKGIISYTDEEVVSSDFVHCKFSSVFDINA 323 Query: 300 GIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 GI LND FVKL+SWYDNE+GYSNR+V+L +M+ ++ Sbjct: 324 GIMLNDTFVKLVSWYDNEWGYSNRLVELAHYMSVQD 359 >5UR0-A nrPDB Length = 349 Score = 433 bits (1114), Expect = e-122, Method: Compositional matrix adjust. Identities = 206/330 (62%), Positives = 254/330 (76%), Gaps = 2/330 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VK+G+NGFGRIGRLV RA+ V++VAIND + YM+YM +YD+ HGKFHG ++ Sbjct: 18 VKIGINGFGRIGRLVFRASLERTDVEVVAINDIMMTPEYMIYMIKYDTVHGKFHGKLEHT 77 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +++NG I + ERDP ++ WG EYVVESTG+FT ++ A HL+GGAKRV+ISA Sbjct: 78 EKSIIVNGREIHVLCERDPEQLPWGQHNVEYVVESTGIFTKLDSAAKHLKGGAKRVVISA 137 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 P AD P FVMGVN+ +Y + +I+NASCTTNCLAP+A V+H+NFGIVEGLMTTVHA+TA Sbjct: 138 P-ADTPTFVMGVNNHEYKPEMTVINNASCTTNCLAPIAAVLHENFGIVEGLMTTVHAVTA 196 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQ TVD PS K WR GR A NIIP+STGAAKAVG VIP LNGKLTGMAFRVPT +VSVV Sbjct: 197 TQPTVDAPSRKDWRGGRAAGYNIIPSSTGAAKAVGLVIPSLNGKLTGMAFRVPTVDVSVV 256 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGP-LKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 DLTCRLEKPA I + +K ASE KGIL +T+ +VVSSDF D+ SST+D+ A I Sbjct: 257 DLTCRLEKPATKKQIDEAMKAASESERFKGILKFTDEEVVSSDFVHDSASSTYDSKASIC 316 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 LN+HFVK+++WYDNE+GYSNRV+DL+ A Sbjct: 317 LNEHFVKVVAWYDNEWGYSNRVLDLIKSTA 346 >6OK4-A nrPDB Length = 342 Score = 380 bits (975), Expect = e-106, Method: Compositional matrix adjust. Identities = 189/330 (57%), Positives = 234/330 (70%), Gaps = 3/330 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAF-NSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 +++ +NGFGRIGRLV R + +++VAIND + + + Y+F+YDSTHG F Sbjct: 9 MRIVINGFGRIGRLVLRQILKRNSPIEVVAIND-LVAGDLLTYLFKYDSTHGSFAPQATF 67 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 +G LV+ I E+D K+ W D + VVESTG+F + A HL GAKRV+I+ Sbjct: 68 SDGCLVMGERKIRFLAEKDVQKLPWKDLDVDVVVESTGLFVNRDDAAKHLDSGAKRVLIT 127 Query: 123 APS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP+ D P FVMGVNH+++D + IISNASCTTNCLAPLAKV+ DNFGI EGLMTTVHA Sbjct: 128 APAKGDVPTFVMGVNHQQFDPADVIISNASCTTNCLAPLAKVLLDNFGIEEGLMTTVHAA 187 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQ VDGPS K WR GRGA QNIIPASTGAAKAVG +PEL GKLTGMAFRVP A+VS Sbjct: 188 TATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS 247 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLT +L Y+ I + VK A+ +K I+ YTE VVSSDF +SS FDA AG+ Sbjct: 248 VVDLTVKLSSATTYEAICEAVKHAANTSMKNIMYYTEEAVVSSDFIGCEYSSIFDAQAGV 307 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHM 331 ALND F KL++WYDNE GY+ R+VDL+ ++ Sbjct: 308 ALNDRFFKLVAWYDNEIGYATRIVDLLEYV 337 >1NPT-O nrPDB Length = 334 Score = 353 bits (907), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 178/333 (53%), Positives = 229/333 (68%), Gaps = 4/333 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGR V RAA + +++VA+ND D N + ++ +YDS HG+ V Sbjct: 2 VKVGINGFGRIGRNVFRAALKNPDIEVVAVND-LTDANTLAHLLKYDSVHGRLDAEVSVN 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 LV+NG I + ERDP + WG+ G + VVESTG FT E A HL+ GAK+VIISA Sbjct: 61 GNNLVVNGKEIIVKAERDPENLAWGEIGVDIVVESTGRFTKREDAAKHLEAGAKKVIISA 120 Query: 124 PSADAPM-FVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + + VMGVN +KYD + +ISNAS TTNCLAP AKV+H+ FGIV G+MTTVH+ Sbjct: 121 PAKNEDITIVMGVNQDKYDPKAHHVISNASATTNCLAPFAKVLHEQFGIVRGMMTTVHSY 180 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P L R R A ++IIP +TGAAKAV V+PEL GKL GMA RVPT NVS Sbjct: 181 TNDQRILDLPHKDLRR-ARAAAESIIPTTTGAAKAVALVLPELKGKLNGMAMRVPTPNVS 239 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDL LEK +++ +K A+EG LKGIL Y+E +VS D+N T SST DA + + Sbjct: 240 VVDLVAELEKEVTVEEVNAALKAAAEGELKGILAYSEEPLVSRDYNGSTVSSTIDALSTM 299 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 ++ VK++SWYDNE GYS+RVVDL A++ASK Sbjct: 300 VIDGKMVKVVSWYDNETGYSHRVVDLAAYIASK 332 >2X0N-A nrPDB Length = 359 Score = 349 bits (895), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 185/352 (52%), Positives = 242/352 (68%), Gaps = 20/352 (5%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 +KVG+NGFGRIGR+V +A + G ++D+VA+ D D Y Y +YDS HGKF + Sbjct: 3 IKVGINGFGRIGRMVFQALCDDGLLGNEIDVVAVVDMNTDARYFAYQMKYDSVHGKFKHS 62 Query: 60 VK--------AENGKLVINGNPITIFQ-ERDPSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 V A++ LV+NG+ I + +R+P+ + WG G EYV+ESTG+FT A Sbjct: 63 VSTTKSKPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTVKSAAEG 122 Query: 111 HLQGGAKRVIISAP-SADAPMFVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKV-IHDN 167 HL+GGA++V+ISAP S A FVMGVNH Y+ ++SNASCTTNCLAPL V + + Sbjct: 123 HLRGGARKVVISAPASGGAKTFVMGVNHNNYNPREQHVVSNASCTTNCLAPLVHVLVKEG 182 Query: 168 FGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGK 227 FGI GLMTTVH+ TATQKTVDG S K WR GR A NIIP++TGAAKAVG VIP GK Sbjct: 183 FGISTGLMTTVHSYTATQKTVDGVSVKDWRGGRAAALNIIPSTTGAAKAVGMVIPSTQGK 242 Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFN 287 LTGMAFRVPTA+VSVVDLT + +I +K+AS+ +K ILGYT+ ++VS+DF Sbjct: 243 LTGMAFRVPTADVSVVDLTFIATRDTSIKEIDAALKRASKTYMKNILGYTDEELVSADFI 302 Query: 288 SDTHSSTFDAGAGIALN----DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 SD+ SS +D+ A + N F K++SWYDNE+GYS+RVVDL+ HMA+++ Sbjct: 303 SDSRSSIYDSKATLQNNLPNERRFFKIVSWYDNEWGYSHRVVDLVRHMAARD 354 >1ML3-A nrPDB Length = 359 Score = 341 bits (875), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 181/352 (51%), Positives = 240/352 (68%), Gaps = 20/352 (5%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 +KVG+NGFGRIGR+V +A G ++D+VA+ D D Y Y +YD+ HGKF Sbjct: 3 IKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMNTDAEYFAYQMRYDTVHGKFKYE 62 Query: 60 VK--------AENGKLVINGNPITIFQ-ERDPSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 V A++ LV+NG+ I + +R+P+ + WG G EYV+ESTG+FT A Sbjct: 63 VTTTKSSPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAAEG 122 Query: 111 HLQGGAKRVIISAP-SADAPMFVMGVNHEKYDNSLK-IISNASCTTNCLAPLAKV-IHDN 167 HL+GGA++V+ISAP S A VMGVNH +Y+ S ++SNASCTTNCLAP+ V + + Sbjct: 123 HLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHVVSNASCTTNCLAPIVHVLVKEG 182 Query: 168 FGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGK 227 FG+ GLMTT+H+ TATQKTVDG S K WR GR A NIIP++TGAAKAVG VIP GK Sbjct: 183 FGVQTGLMTTIHSYTATQKTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQGK 242 Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFN 287 LTGM+FRVPT +VSVVDLT + +I +K+AS+ +KGILGYT+ ++VS+DF Sbjct: 243 LTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRASKTYMKGILGYTDEELVSADFI 302 Query: 288 SDTHSSTFDAGAGIALN----DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 +D SS +D+ A + N F K++SWYDNE+GYS+RVVDL+ HMASK+ Sbjct: 303 NDNRSSIYDSKATLQNNLPKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKD 354 >1I33-A nrPDB Length = 360 Score = 332 bits (851), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 176/352 (50%), Positives = 241/352 (68%), Gaps = 20/352 (5%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 +KVG+NGFGRIGR+V +A + G ++D+VA+ D + Y Y ++D+ HG+ T Sbjct: 3 IKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYT 62 Query: 60 VKAENGK--------LVINGNPITIFQ-ERDPSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 V+A LV+NG+ I + +R+P+ + WG G +YV+ESTG+FT KA Sbjct: 63 VEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEG 122 Query: 111 HLQGGAKRVIISAP-SADAPMFVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVI-HDN 167 H++GGAK+V+ISAP S A VMGVN +Y S ++SNASCTTNCLAP+ V+ +N Sbjct: 123 HIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKEN 182 Query: 168 FGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGK 227 FGI GLMTT+H+ TATQKTVDG S K WR GR A NIIP++TGAAKAVG VIP GK Sbjct: 183 FGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGK 242 Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFN 287 LTGM+FRVPT +VSVVDLT R + +I K +K+A++ +KGILG+T+ ++VS+DF Sbjct: 243 LTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFI 302 Query: 288 SDTHSSTFDAGAGIALN----DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 +D SS +D+ A + N F K++SWYDNE+ YS+RVVDL+ +MA+K+ Sbjct: 303 NDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKD 354 >3HJA-A nrPDB Length = 356 Score = 315 bits (806), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 170/338 (50%), Positives = 226/338 (66%), Gaps = 11/338 (3%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 G +K+ +NGFGRIGR V + AF G +DIVAIND D + ++ +YDST G ++ V+ Sbjct: 20 GSMKLAINGFGRIGRNVFKIAFERG-IDIVAIND-LTDPKTLAHLLKYDSTFGVYNKKVE 77 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFT--TMEKAG--AHL-QGGA 116 + +G +V++G I I ERDP + W G + V+ESTGVF+ T +K G H+ GA Sbjct: 78 SRDGAIVVDGREIKIIAERDPKNLPWAKLGIDVVIESTGVFSSATSDKGGYLDHVNHAGA 137 Query: 117 KRVIISAPSADA-PMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLM 175 K+VI++ P+ D V+GVN ++ LK +SNASCTTNCLAPLAKV+H++FGI +GLM Sbjct: 138 KKVILTVPAKDEIKTIVLGVNDHDINSDLKAVSNASCTTNCLAPLAKVLHESFGIEQGLM 197 Query: 176 TTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRV 235 TTVHA T Q+ +D P L R R A +IIP STGAAKAVG V+PEL GKL G + RV Sbjct: 198 TTVHAYTNDQRILDLPHSDLRR-ARAAALSIIPTSTGAAKAVGLVLPELKGKLNGTSMRV 256 Query: 236 PTANVSVVDLTCRLEKP-AKYDDIKKVVKQASEGP-LKGILGYTEHQVVSSDFNSDTHSS 293 P S+VDLT +L+K ++I V+++ASE P LKGILGYTE +VSSD ++HSS Sbjct: 257 PVPTGSIVDLTVQLKKKDVTKEEINSVLRKASETPELKGILGYTEDPIVSSDIKGNSHSS 316 Query: 294 TFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHM 331 D + L + F K++SWYDNEFGYS RVVDL + Sbjct: 317 IVDGLETMVLENGFAKILSWYDNEFGYSTRVVDLAQKL 354 >1HDG-O nrPDB Length = 332 Score = 312 bits (800), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 161/327 (49%), Positives = 212/327 (64%), Gaps = 5/327 (1%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDI--VAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 +V +NGFGRIGRLV R + DI VAIND D + ++ +YDS H KF G V+ Sbjct: 2 RVAINGFGRIGRLVYRIIYERKNPDIEVVAIND-LTDTKTLAHLLKYDSVHKKFPGKVEY 60 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 L+++G I +F E DPSK+ W D G ++V+ESTGVF EKA HLQ GAK+VII+ Sbjct: 61 TENSLIVDGKEIKVFAEPDPSKLPWKDLGVDFVIESTGVFRNREKAELHLQAGAKKVIIT 120 Query: 123 APSADAPM-FVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP+ + V+G N ++ IIS ASCTTN +AP+ KV+H+ FGIV G++TTVH+ Sbjct: 121 APAKGEDITVVIGCNEDQLKPEHTIISCASCTTNSIAPIVKVLHEKFGIVSGMLTTVHSY 180 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P L R R A NIIP +TGAAKAV V+PE+ GKL GMA RVPT + S Sbjct: 181 TNDQRVLDLPHKDLRR-ARAAAVNIIPTTTGAAKAVALVVPEVKGKLDGMAIRVPTPDGS 239 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + DLT +EK +++ V+K+A+EG LKGI+GY + +VSSD T S FDA Sbjct: 240 ITDLTVLVEKETTVEEVNAVMKEATEGRLKGIIGYNDEPIVSSDIIGTTFSGIFDATITN 299 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLM 328 + VK+ SWYDNE+GYSNRVVD + Sbjct: 300 VIGGKLVKVASWYDNEYGYSNRVVDTL 326 >2EP7-A nrPDB Length = 342 Score = 304 bits (778), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 158/341 (46%), Positives = 230/341 (67%), Gaps = 13/341 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR RA++ +++IVAIND D ++ ++ +YDS HG F G+V+A+ Sbjct: 3 IKVGINGFGRIGRSFFRASWGREEIEIVAIND-LTDAKHLAHLLKYDSVHGIFKGSVEAK 61 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + +V++G I +F ++DPS+I WGD G + V+E+TGVF E A HLQGGAK+VII+A Sbjct: 62 DDSIVVDGKEIKVFAQKDPSQIPWGDLGVDVVIEATGVFRDRENASKHLQGGAKKVIITA 121 Query: 124 PSADAPM-FVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + + V+GVN EKY+ IISNASCTTNCLAP KV+++ FG+ +G M TVHA Sbjct: 122 PAKNPDITVVLGVNEEKYNPKEHNIISNASCTTNCLAPCVKVLNEAFGVEKGYMVTVHAY 181 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P K +R R A NI+P +TGAAKA+G+VIPEL GKL G A RVP + S Sbjct: 182 TNDQRLLDLPH-KDFRRARAAAINIVPTTTGAAKAIGEVIPELKGKLDGTARRVPVPDGS 240 Query: 242 VVDLTCRLEK-PAKYDDIKKVVKQASEG-------PLKGILGYTEHQVVSSDFNSDTHSS 293 ++DLT + K P+ +++ + ++A++ LK IL Y E +VS+D + HS+ Sbjct: 241 LIDLTVVVNKAPSSVEEVNEKFREAAQKYRESGKVYLKEILQYCEDPIVSTDIVGNPHSA 300 Query: 294 TFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 FDA + D+ V + +WYDNE+GYS R+ DL+ ++A + Sbjct: 301 IFDAPLTQVI-DNLVHIAAWYDNEWGYSCRLRDLVIYLAER 340 >4BOY-A nrPDB Length = 354 Score = 302 bits (773), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 157/335 (46%), Positives = 217/335 (64%), Gaps = 7/335 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFN---SGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFH-GT 59 V+V +NGFGRIGR R + K++IV IND D ++ +YDS G F Sbjct: 19 VRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTS-DPRTNAHLLKYDSMLGIFQDAE 77 Query: 60 VKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRV 119 + A++ + G+ + +R+P + W G + V+E+TGVFT+ E A HL GAK+V Sbjct: 78 ITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKV 137 Query: 120 IISAP-SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 +I+AP + P +V+GVNH YD S I+SNASCTTNCLAP+ KV+H+ FGI +G+MTT Sbjct: 138 LITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTT 197 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D L R A+ NI+P STGAAKAVG VIPEL GKL G+A RVPT Sbjct: 198 HSYTGDQRLLDASHRDLRRARAAAM-NIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTP 256 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVD ++EKP + + +V+K+ASE +KGI+ Y+E ++VSSD+ SS DA Sbjct: 257 NVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDAS 316 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + L + VK+++WYDNE+GYS RV+DL HMA+ Sbjct: 317 LTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAA 351 >3GNQ-A nrPDB Length = 344 Score = 301 bits (771), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 165/336 (49%), Positives = 219/336 (65%), Gaps = 10/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGK---VDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 ++V +NG+GRIGR RA + +GK ++IVAIND D ++ QYD+ HGKF G V Sbjct: 11 IRVAINGYGRIGRNTLRAFYENGKKHDLEIVAIND-LGDAKTNAHLTQYDTAHGKFPGEV 69 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 + LV+NG+ I + R+P+++ WG+ G + V+E TG FT+ EKA AHL+GGAK+VI Sbjct: 70 SVDGDYLVVNGDRIRVLANRNPAELPWGELGVDVVMECTGFFTSKEKASAHLKGGAKKVI 129 Query: 121 ISAP---SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTT 177 ISAP DA + V GVNH+ +ISNASCTTNCLAPL K ++D G+ GLMTT Sbjct: 130 ISAPGGKDVDATI-VYGVNHDVLKAEHTVISNASCTTNCLAPLVKPLNDKIGLETGLMTT 188 Query: 178 VHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPT 237 +HA T Q D L R R A + IP TGAA AVG V+PELNGKL G A RVPT Sbjct: 189 IHAYTNDQVLTDVYHEDL-RRARSATHSQIPTKTGAAAAVGLVLPELNGKLDGYAIRVPT 247 Query: 238 ANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDA 297 NVS+VDL+ ++ ++ ++K+ASEG LKGILGY E +VS DFN + SSTFDA Sbjct: 248 INVSIVDLSFIAKRDTTAAEVNAIMKEASEGALKGILGYNEAPLVSIDFNHNPASSTFDA 307 Query: 298 GAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 ++ VK+ SWYDNE+G+SNR++D +A+ Sbjct: 308 TL-TKVSGRLVKVSSWYDNEWGFSNRMLDTAIALAN 342 >3DOC-A nrPDB Length = 335 Score = 297 bits (761), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 151/326 (46%), Positives = 217/326 (66%), Gaps = 5/326 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDI--VAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 V+V +NGFGRIGR + RA SG+ DI VAIND + ++ +YDS HG+F V+ Sbjct: 3 VRVAINGFGRIGRNILRAIVESGRTDIQVVAIND-LGPVETNAHLLRYDSVHGRFPKEVE 61 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + + PI + R+P+++ W + + +E TG+FT+ +KA HL+ GAKRVI+ Sbjct: 62 VAGDTIDVGYGPIKVHAVRNPAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVIV 121 Query: 122 SAPSADAPMFVM-GVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 SAP+ A + V+ GVN++K +ISNASCTTNCLAP+A+V++D GI +G MTT+H+ Sbjct: 122 SAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAPVAQVLNDTIGIEKGFMTTIHS 181 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q T+D L+R R A ++IP STGAAKAVG V+PEL GKL G+A RVPT NV Sbjct: 182 YTGDQPTLDTMHKDLYR-ARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVAIRVPTPNV 240 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLT ++ +++ +++A+ G LKGILGYT+ ++VS DFN D+HSS F Sbjct: 241 SVVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQT 300 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVD 326 ++ V+++SWYDNE+G+S+R+ D Sbjct: 301 KVMDGTMVRILSWYDNEWGFSSRMSD 326 >1OBF-O nrPDB Length = 335 Score = 295 bits (756), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 161/335 (48%), Positives = 216/335 (64%), Gaps = 8/335 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGK---VDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 ++V +NG+GRIGR + RA + GK ++IVAIND D ++ +YD+ HGKF GTV Sbjct: 2 IRVAINGYGRIGRNILRAHYEGGKSHDIEIVAIND-LGDPKTNAHLTRYDTAHGKFPGTV 60 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 +V+NG+ I + R+P+++ WG + V+E TG FTT EKAGAH++GGAK+VI Sbjct: 61 SVNGSYMVVNGDKIRVDANRNPAQLPWGALKVDVVLECTGFFTTKEKAGAHIKGGAKKVI 120 Query: 121 ISAPS-ADA-PMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 ISAP AD V GVNH ++ +ISNASCTTNCLAPL K ++D G+ +GLMTTV Sbjct: 121 ISAPGGADVDATVVYGVNHGTLKSTDTVISNASCTTNCLAPLVKPLNDKLGLQDGLMTTV 180 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 HA T Q D L R R A ++IP TGAA AVG V+PEL+GKL G A RVPT Sbjct: 181 HAYTNNQVLTDVYHEDL-RRARSATMSMIPTKTGAAAAVGDVLPELDGKLNGYAIRVPTI 239 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVS+VDL+ ++ +++ ++K ASEG LKGIL Y +VS D+N D SST DA Sbjct: 240 NVSIVDLSFVAKRNTTVEEVNGILKAASEGELKGILDYNTEPLVSVDYNHDPASSTVDAS 299 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 ++ VK+ SWYDNE+G+SNR++D + S Sbjct: 300 L-TKVSGRLVKVSSWYDNEWGFSNRMLDTTVALMS 333 >3L0D-A nrPDB Length = 356 Score = 295 bits (754), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 150/326 (46%), Positives = 211/326 (64%), Gaps = 5/326 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDI--VAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 V+V +NGFGRIGR + RA SG+ DI VA+ND + ++ +YDS HG F GTV+ Sbjct: 24 VRVAINGFGRIGRNILRAIIESGRQDIEVVALND-LGSVETNAHLLRYDSVHGCFPGTVQ 82 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + I + I +F ERDP+++ W + +E TG+FT +KA AHL GAKRV++ Sbjct: 83 VVGDAIDIGSSLIKVFAERDPAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVLV 142 Query: 122 SAPSADAPMFVM-GVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 SAPS A + V+ GVNH+ +ISNASCTTNCLAP+A+V+H+ GI +G MTT+H+ Sbjct: 143 SAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAPVAQVLHNTVGIEKGFMTTIHS 202 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q +D L+R R A ++IP STGAAKAVG V+PEL G L G++ RVPT NV Sbjct: 203 YTGDQPVLDTMHRDLYR-ARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPNV 261 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLT ++ ++I ++ A++G LKGIL YT+ ++VS DFN + HS+ F Sbjct: 262 SVVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQT 321 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVD 326 ++ +++ WYDNE+G+SNR+ D Sbjct: 322 KVIDGQLCRVLVWYDNEWGFSNRMCD 347 >5M6D-A nrPDB Length = 355 Score = 291 bits (746), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 158/336 (47%), Positives = 203/336 (60%), Gaps = 10/336 (2%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 G VKVG+NGFGRIGRL R N V++ IND D + ++ +YD+T G+F GTV+ Sbjct: 21 GVVKVGINGFGRIGRLAFRRIQNVEGVEVTRIND-LTDPVMLAHLLKYDTTQGRFDGTVE 79 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + G +NG I + ERDP +I W G E V+E+TG F E A HL+GGAK+V+I Sbjct: 80 VKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAKKEAAEKHLKGGAKKVVI 139 Query: 122 SAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 +AP D V NH+ D + +IS ASCTTNCLAP+AK + DNFG+VEGLMTT+HA Sbjct: 140 TAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMAKALQDNFGVVEGLMTTIHA 199 Query: 181 ITATQKTVDGP-SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTAN 239 T Q +DGP G R R NI+P STGAAKA+G VIPELNGKL G A RVPT Sbjct: 200 YTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPTPT 259 Query: 240 VSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGA 299 SV +L LEK D++ +K AS GYTE +VSSD ++ S FDA Sbjct: 260 GSVTELVAVLEKNVTVDEVNAAMKAASNES----YGYTEDPIVSSDIVGMSYGSLFDATQ 315 Query: 300 GIALN---DHFVKLISWYDNEFGYSNRVVDLMAHMA 332 L+ VK++SWYDNE Y+ ++V + + A Sbjct: 316 TKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFA 351 >4DIB-A nrPDB Length = 345 Score = 290 bits (742), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 152/321 (47%), Positives = 211/321 (65%), Gaps = 4/321 (1%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 +V +NGFGRIGR+V R A +IVAIN + + ++ +YD+ HGKF GTV+A Sbjct: 6 RVAINGFGRIGRMVFRQAIKESAFEIVAINASYPS-ETLAHLIKYDTVHGKFDGTVEAFE 64 Query: 65 GKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAP 124 L+++G I + RDP ++ W D G E V+E+TG F + EKA H++ GAK+VI++AP Sbjct: 65 DHLLVDGKMIRLLNNRDPKELPWTDLGVEVVIEATGKFNSKEKAILHVEAGAKKVILTAP 124 Query: 125 SADAPM-FVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 + + V+GVN ++ D +ISNASCTTNCLAP+ KV+ + FGI GLMTTVHA T Sbjct: 125 GKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVVKVLDEQFGIENGLMTTVHAYT 184 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 QK +D P L R R Q+IIP +TGAAKA+ KV+P LNGKL GMA RVPT NVS+ Sbjct: 185 NDQKNIDNPHKDL-RRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSL 243 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDL +++ + I K + G LKGI+ ++E +VS DFN++THS+ D + + Sbjct: 244 VDLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMV 303 Query: 303 LNDHFVKLISWYDNEFGYSNR 323 + D VK+++WYDNE+GYS R Sbjct: 304 MGDRKVKVLAWYDNEWGYSRR 324 >5VMT-A nrPDB Length = 342 Score = 287 bits (735), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 150/336 (44%), Positives = 205/336 (61%), Gaps = 10/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KV +NGFGRIGRL R + +++ A+ND ++++F+YDST G+F GT + + Sbjct: 11 IKVAINGFGRIGRLALRQIEKAHGIEVAAVND-LTPAEMLLHLFKYDSTQGRFQGTAELK 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + +V+NG I +F +P ++ WG+ G + V+E TG FT KA AH++ GA++V+ISA Sbjct: 70 DDAIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISA 129 Query: 124 PSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P D V GVN + D S +IS ASCTTNCLAP+A V+ FG+VEGLMTT+HA T Sbjct: 130 PGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAAVLQKEFGVVEGLMTTIHAYT 189 Query: 183 ATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q T+D P K R R A NI+P STGAAKA+G VIPELNGKL G A RVP A S Sbjct: 190 GDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATGS 249 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + +L LE+PA ++I +K AS GY E Q+VSSD + S FDA Sbjct: 250 LTELVSVLERPATKEEINAAMKAASSES----YGYNEDQIVSSDVVGIEYGSLFDATQTR 305 Query: 302 ALN---DHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + VK ++WYDNE Y+ ++V + + A K Sbjct: 306 VMTVGGKQLVKTVAWYDNEMSYTCQLVRTLEYFAGK 341 >1CER-O nrPDB Length = 331 Score = 284 bits (726), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 160/327 (48%), Positives = 213/327 (65%), Gaps = 6/327 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR V R + G V++ IND D + ++ +YDS + +F G V + Sbjct: 1 MKVGINGFGRIGRQVFRILHSRG-VEVALIND-LTDNKTLAHLLKYDSIYHRFPGEVAYD 58 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + L ++G I +DP +I W +AG V+ESTGVFT +KA AHL+GGAK+VII+A Sbjct: 59 DQYLYVDGKAIRATAVKDPKEIPWAEAGVGVVIESTGVFTDADKAKAHLEGGAKKVIITA 118 Query: 124 PSADAPM-FVMGVNHEKYDNSLK-IISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + VMGVNHE YD S IISNASCTTN LAP+ KV+ + FG+ + LMTTVH+ Sbjct: 119 PAKGEDITIVMGVNHEAYDPSRHHIISNASCTTNSLAPVMKVLEEAFGVEKALMTTVHSY 178 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P L R R A NIIP +TGAAKA V+P L G+ GMA RVPTA S Sbjct: 179 TNDQRLLDLPHKDL-RRARAAAINIIPTTTGAAKATALVLPSLKGRFDGMALRVPTATGS 237 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + D+T L++ +++ +K A+EGPLKGIL YTE ++V D D HSS DA Sbjct: 238 ISDITALLKREVTAEEVNAALKAAAEGPLKGILAYTEDEIVLQDIVMDPHSSIVDAKLTK 297 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLM 328 AL + VK+ +WYDNE+GY+NRV DL+ Sbjct: 298 ALGN-MVKVFAWYDNEWGYANRVADLV 323 >6FZH-A nrPDB Length = 336 Score = 281 bits (719), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 155/335 (46%), Positives = 198/335 (59%), Gaps = 11/335 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRL R N V++ IND D N + ++ +YD+T G+F GTV+ + Sbjct: 3 VKVGINGFGRIGRLAFRRIQNIEGVEVTRIND-LTDPNMLAHLLKYDTTQGRFDGTVEVK 61 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQG-GAKRVIIS 122 G +NGN I + ERDP I W G E V+E+TG F E A HL GAK+V+I+ Sbjct: 62 EGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAKKEAAEKHLHANGAKKVVIT 121 Query: 123 APSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP D V NH+ D + +IS ASCTTNCLAP+AK +HD FGI +GLMTT+HA Sbjct: 122 APGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALHDAFGIQKGLMTTIHAY 181 Query: 182 TATQKTVDGP-SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q +DGP G R R NI+P STGAAKA+G VIPELNGKL G A RVP Sbjct: 182 TGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTG 241 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SV +L L+K D+I +K AS GYTE +VSSD ++ S FDA Sbjct: 242 SVTELVVTLDKNVSVDEINAAMKAASNDS----FGYTEDPIVSSDIVGVSYGSLFDATQT 297 Query: 301 IALN---DHFVKLISWYDNEFGYSNRVVDLMAHMA 332 + VK++SWYDNE Y+ ++V + + A Sbjct: 298 KVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFA 332 >6FZI-A nrPDB Length = 332 Score = 281 bits (719), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 151/336 (44%), Positives = 208/336 (61%), Gaps = 10/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKV +NGFGRIGRL R ++ + ++VAIND D + ++F+YDS G+F+G ++ + Sbjct: 2 VKVAINGFGRIGRLALRLMIDNPEFEVVAIND-LTDAKTLAHLFKYDSAQGRFNGEIEVK 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 G V+NG I + + +P+++ WG+ G + V+E TG F + EKA AHL GAK+V+ISA Sbjct: 61 EGAFVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISA 120 Query: 124 PSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P+ D P V VNH+ D S +IS ASCTTNCLAP+AK ++DNFG+ +G MTT+HA T Sbjct: 121 PAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAKALNDNFGLNKGFMTTIHAYT 180 Query: 183 ATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q T+D P K R R A NI+P STGAAKA+G VIPEL GKL G A RVP S Sbjct: 181 NDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS 240 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + +L C L+K +++ +K AS GYTE +VSSD + S FDA Sbjct: 241 LTELVCTLDKKVTVEEVNAAMKAASNES----FGYTEDPIVSSDVIGISFGSLFDATQTK 296 Query: 302 ALN---DHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + VK+ SWYDNE Y+N+++ + + SK Sbjct: 297 IMEVDGQQLVKVASWYDNEASYTNQLIRTLKCLVSK 332 >1VC2-A nrPDB Length = 331 Score = 278 bits (711), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 158/333 (47%), Positives = 212/333 (63%), Gaps = 6/333 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR V R G V++ IND D + ++ +YDST+G+F G V + Sbjct: 1 MKVGINGFGRIGRQVFRILHERG-VEVALIND-LTDNKTLAHLLKYDSTYGRFPGAVGYD 58 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 L ++G I +DP +I W AG VVESTGVFT EKA AHL+ GAK+VII+A Sbjct: 59 EENLYVDGKAIRATAIKDPREIPWKQAGVGVVVESTGVFTDGEKARAHLEAGAKKVIITA 118 Query: 124 PSADAPM-FVMGVNHEKYDNSLK-IISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + + V+GVNHE+YD + I+SNASCTTN LAP+ KV+ FG+ + LMTTVH+ Sbjct: 119 PAKNEDITVVLGVNHEQYDPAKHHILSNASCTTNSLAPVMKVLEKAFGVEKALMTTVHSY 178 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P L R R A NIIP +TGAAKA V+P L G+ GMA RVPT S Sbjct: 179 TNDQRLLDLPHKDL-RRARAAALNIIPTTTGAAKATALVLPSLKGRFDGMALRVPTPTGS 237 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + D+T L++ +++ +K A+EGPLKGIL YTE ++V D D HSS D Sbjct: 238 ISDITALLKREVTAEEVNAALKAAAEGPLKGILAYTEDEIVLRDIVMDPHSSIVDGKLTK 297 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 A+ + VK+ +WYDNE+GY+NRV DL+ + K Sbjct: 298 AIGN-LVKVFAWYDNEWGYANRVADLVELVLKK 329 >5JY6-A nrPDB Length = 356 Score = 278 bits (710), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 149/335 (44%), Positives = 202/335 (60%), Gaps = 11/335 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRL R N V++ IND D N + ++ +YD+T G+F GTV+ + Sbjct: 23 VKVGINGFGRIGRLAFRRIQNVEGVEVTRIND-LTDPNMLAHLLKYDTTQGRFDGTVEVK 81 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHL-QGGAKRVIIS 122 G +NG + + ER+P+ I W G E V+E+TG F + EKA H+ + GAK+V+I+ Sbjct: 82 EGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVIT 141 Query: 123 APSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP D V NH+ D + +IS ASCTTNCLAP+AK + DNFG+ +GLMTT+HA Sbjct: 142 APGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAY 201 Query: 182 TATQKTVDGP-SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q +DGP G R R NI+P STGAAKA+G VIPELNGKL G A RVP Sbjct: 202 TGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTG 261 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDA--- 297 SV +L LEK +++ +K A+ GYTE +VSSD ++ S FDA Sbjct: 262 SVTELVATLEKDVTVEEVNAAMKAAANDS----YGYTEDPIVSSDIVGISYGSLFDATQT 317 Query: 298 GAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 + VK++SWYDNE Y++++V + + A Sbjct: 318 KVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFA 352 >3VAZ-P nrPDB Length = 344 Score = 277 bits (708), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 150/336 (44%), Positives = 209/336 (62%), Gaps = 11/336 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKV +NGFGRIGRL R +++VA+ND D + + ++ +YD+ G+F G V+ Sbjct: 11 VKVAINGFGRIGRLAFRRIQEVEGLEVVAVND-LTDDDMLAHLLKYDTMQGRFTGEVEVV 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +G +NG + F E D SK+ W D + V+E TG +T +KA AH++ GAK+V+ISA Sbjct: 70 DGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISA 129 Query: 124 P-SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P + D V NH++ D S ++S ASCTTN LAP+AKV++D+FG+VEGLMTT+HA T Sbjct: 130 PATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYT 189 Query: 183 ATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q T D P K R R A +NIIP STGAAKA+GKVIPE++GKL G A RVP A S Sbjct: 190 GDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGS 249 Query: 242 VVDLTCRLEKP-AKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 + +LT LEK + + + +K AS GYTE ++VSSD T+ S FDA Sbjct: 250 LTELTVVLEKQDVTVEQVNEAMKNASNES----FGYTEDEIVSSDVVGMTYGSLFDATQT 305 Query: 301 IAL---NDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + + VK+ +WYDNE Y+ ++V +A++A Sbjct: 306 RVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAE 341 >3B1K-A nrPDB Length = 339 Score = 276 bits (706), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 152/337 (45%), Positives = 219/337 (64%), Gaps = 8/337 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVD--IVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 ++V +NGFGRIGR R F D +VAIN+ D ++ +YDS G+F+ + Sbjct: 3 IRVAINGFGRIGRNFLRCWFGRQNTDLEVVAINNTS-DARTAAHLLEYDSVLGRFNADIS 61 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + + +NG + I +R+P + W + + V+ESTGVF T E A H+Q GAK+V+I Sbjct: 62 YDENSITVNGKTMKIVCDRNPLNLPWKEWDIDLVIESTGVFVTAEGASKHIQAGAKKVLI 121 Query: 122 SAPSADAPM--FVMGVNHEKYDNS-LKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 +AP + +V+GVN +Y + +ISNASCTTNCLAP+AKV+HDNFGI++G MTT Sbjct: 122 TAPGKGEGVGTYVIGVNDSEYRHEDFAVISNASCTTNCLAPVAKVLHDNFGIIKGTMTTT 181 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D L R A+ NI+P +TGAAKAV VIPEL GKL G+A RVPT Sbjct: 182 HSYTLDQRILDASHRDLRRARAAAV-NIVPTTTGAAKAVALVIPELKGKLNGIALRVPTP 240 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVDL ++EKP + + +V+++AS+ +KGI+ Y++ +VSSDF SS D+ Sbjct: 241 NVSVVDLVVQVEKPTITEQVNEVLQKASQTTMKGIIKYSDLPLVSSDFRGTDESSIVDSS 300 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 + ++ VK+I+WYDNE+GYS RVVDL A +A+++ Sbjct: 301 LTLVMDGDLVKVIAWYDNEWGYSQRVVDL-AELAARK 336 >2DUU-A nrPDB Length = 380 Score = 276 bits (705), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 152/337 (45%), Positives = 219/337 (64%), Gaps = 8/337 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVD--IVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 ++V +NGFGRIGR R F D +VAIN+ D ++ +YDS G+F+ + Sbjct: 3 IRVAINGFGRIGRNFLRCWFGRQNTDLEVVAINNTS-DARTAAHLLEYDSVLGRFNADIS 61 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + + +NG + I +R+P + W + + V+ESTGVF T E A H+Q GAK+V+I Sbjct: 62 YDENSITVNGKTMKIVCDRNPLNLPWKEWDIDLVIESTGVFVTAEGASKHIQAGAKKVLI 121 Query: 122 SAP--SADAPMFVMGVNHEKYDNS-LKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 +AP + +V+GVN +Y + +ISNASCTTNCLAP+AKV+HDNFGI++G MTT Sbjct: 122 TAPGKAEGVGTYVIGVNDSEYRHEDFAVISNASCTTNCLAPVAKVLHDNFGIIKGTMTTT 181 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D L R A+ NI+P +TGAAKAV VIPEL GKL G+A RVPT Sbjct: 182 HSYTLDQRILDASHRDLRRARAAAV-NIVPTTTGAAKAVALVIPELKGKLNGIALRVPTP 240 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVDL ++EKP + + +V+++AS+ +KGI+ Y++ +VSSDF SS D+ Sbjct: 241 NVSVVDLVVQVEKPTITEQVNEVLQKASQTTMKGIIKYSDLPLVSSDFRGTDESSIVDSS 300 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 + ++ VK+I+WYDNE+GYS RVVDL A +A+++ Sbjct: 301 LTLVMDGDLVKVIAWYDNEWGYSQRVVDL-AELAARK 336 >2PKQ-O nrPDB Length = 368 Score = 275 bits (704), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 155/339 (45%), Positives = 210/339 (61%), Gaps = 9/339 (2%) Query: 3 KVKVGVNGFGRIGRLVTRA--AFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 K+KV +NGFGRIGR R +D+V +ND + ++ +YDS G F V Sbjct: 1 KLKVAINGFGRIGRNFLRCWHGRKDSPLDVVVVNDSG-GVKSATHLLKYDSILGTFKADV 59 Query: 61 KA-ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRV 119 K +N I+G PI + RDP K+ W + G + V+E TGVF AG H+Q GAK+V Sbjct: 60 KIIDNETFSIDGKPIKVVSNRDPLKLPWAELGIDIVIEGTGVFVDGPGAGKHIQAGAKKV 119 Query: 120 IISAPS--ADAPMFVMGVNHEKYDNSL-KIISNASCTTNCLAPLAKVIHDNFGIVEGLMT 176 II+AP+ +D P +V+GVN + Y + + IISNASCTTNCLAP KV+ + GIV+G MT Sbjct: 120 IITAPAKGSDIPTYVVGVNEKDYGHDVANIISNASCTTNCLAPFVKVLDEELGIVKGTMT 179 Query: 177 TVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVP 236 T H+ T Q+ +D S + R R A NI+P STGAAKAV V+P+L GKL G+A RVP Sbjct: 180 TTHSYTGDQRLLDA-SHRDLRRARAAALNIVPTSTGAAKAVSLVLPQLKGKLNGIALRVP 238 Query: 237 TANVSVVDLTCRLEKPA-KYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTF 295 T NVSVVDL +EK +D+ ++A+ GPLKG+L + +VS DF SST Sbjct: 239 TPNVSVVDLVVNIEKVGVTAEDVNNAFRKAAAGPLKGVLDVCDIPLVSVDFRCSDFSSTI 298 Query: 296 DAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 D+ + + VK+++WYDNE+GYS RVVDL +A+K Sbjct: 299 DSSLTMVMGGDMVKVVAWYDNEWGYSQRVVDLADLVANK 337 >1JN0-O nrPDB Length = 335 Score = 272 bits (696), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 152/334 (45%), Positives = 205/334 (61%), Gaps = 4/334 (1%) Query: 3 KVKVGVNGFGRIGRLVTRAAF-NSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 K+KV +NGFGRIGR R +D+V IND + ++ +YDS G F VK Sbjct: 1 KLKVAINGFGRIGRNFLRCWHGKDSPLDVVVINDTG-GVKQASHLLKYDSILGTFDADVK 59 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + G I + +R+P + WGD G + V+E TGVF + AG HLQ GAK+V+I Sbjct: 60 TAGDSAISVGKVIKVVSDRNPVNLPWGDMGIDLVIEGTGVFVDRDGAGKHLQAGAKKVLI 119 Query: 122 SAP-SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 +AP D P +V+GVN E Y ++ IISNASCTTNCLAP KV+ FGI++G MTT H+ Sbjct: 120 TAPGKGDIPTYVVGVNEEGYTHADTIISNASCTTNCLAPFVKVLDQKFGIIKGTMTTTHS 179 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q+ +D L R R A NI+P STGAAKAV V+P+L GKL G+A RVPT NV Sbjct: 180 YTGDQRLLDASHRDL-RRARAACLNIVPTSTGAAKAVALVLPQLKGKLNGIALRVPTPNV 238 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDL ++ K +++ +++++ LKGIL + +VS DF SST D+ Sbjct: 239 SVVDLVVQVSKKTFAEEVNAAFRESADQELKGILSVCDEPLVSIDFRCTDVSSTIDSSLT 298 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + + D VK+I+WYDNE+GYS RVVDL +A+K Sbjct: 299 MVMGDDMVKVIAWYDNEWGYSQRVVDLADIVANK 332 >3RVD-A nrPDB Length = 337 Score = 256 bits (654), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 150/329 (45%), Positives = 202/329 (61%), Gaps = 6/329 (1%) Query: 3 KVKVGVNGFGRIGRLVTRA--AFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 K+KV +NGFGRIGR R +DI+AIND + ++ +YDST G F V Sbjct: 2 KLKVAINGFGRIGRNFLRCWHGRKDSPLDIIAINDTG-GVKQASHLLKYDSTLGIFDADV 60 Query: 61 KAENGKLV-INGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRV 119 K + ++G I + R+PS + W + G + V+E TGVF E AG H++ GAK+V Sbjct: 61 KPSGETAISVDGKIIQVVSNRNPSLLPWKELGIDIVIEGTGVFVDREGAGKHIEAGAKKV 120 Query: 120 IISAP-SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 II+AP D P +V+GVN + Y + IISNASCTTNCLAP KV+ FGI++G MTT Sbjct: 121 IITAPGKGDIPTYVVGVNADAYSHDEPIISNASCTTNCLAPFVKVLDQKFGIIKGTMTTT 180 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D S + R R A NI+P STGAAKAV V+P L GKL G+A RVPT Sbjct: 181 HSYTGDQRLLDA-SHRDLRRARAAALNIVPTSTGAAKAVALVLPNLKGKLNGIALRVPTP 239 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVDL ++ K +++ + ++E LKGIL + +VS DF S+T D+ Sbjct: 240 NVSVVDLVVQVSKKTFAEEVNAAFRDSAEKELKGILDVCDEPLVSVDFRCSDFSTTIDSS 299 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDL 327 + + D VK+I+WYDNE+GYS RVVDL Sbjct: 300 LTMVMGDDMVKVIAWYDNEWGYSQRVVDL 328 >2XF8-A nrPDB Length = 338 Score = 251 bits (640), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 126/336 (37%), Positives = 201/336 (59%), Gaps = 9/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGK---VDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 V+V +NGFGRIGR V RA + SG+ + +VAIN+ D M ++ +YD++HG+F V Sbjct: 2 VRVAINGFGRIGRNVVRALYESGRRAEITVVAINE-LADAAGMAHLLKYDTSHGRFAWEV 60 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 + E +L + + I + ER + W + G + V++ TGV+ + E AH+ GAK+V+ Sbjct: 61 RQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVL 120 Query: 121 ISAPSA---DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTT 177 S P + DA + V GVN ++ +I+SNASCTTNC+ P+ K++ D +GI G +TT Sbjct: 121 FSHPGSNDLDATV-VYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTT 179 Query: 178 VHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPT 237 +H+ Q+ +D L R R A Q+IIP T A + + P+ N + +A RVPT Sbjct: 180 IHSAMHDQQVIDAYHPDL-RRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPT 238 Query: 238 ANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDA 297 NV+ +DL+ ++KP K +++ ++++A++G GI+ YTE +VS DFN D HS+ D Sbjct: 239 INVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDG 298 Query: 298 GAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 H +K + W DNE+G++NR++D MA+ Sbjct: 299 TQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAT 334 >6IQV-A nrPDB Length = 340 Score = 244 bits (622), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 141/340 (41%), Positives = 198/340 (58%), Gaps = 13/340 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGK----VDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 VK+G+NGFGRIGRL R G+ +++VAIND + ++ +YDSTHG + Sbjct: 3 VKIGINGFGRIGRLAFRRILELGEKSSDIEVVAIND-LTSPALLAHLLKYDSTHGTLNAD 61 Query: 60 VKAENGKLVINGNPITIFQERDPSKIKW-GDAGAEYVVESTGVFTTMEKAGAHLQGGAKR 118 V A + +V+NG ++ E I W + G ++V+E TG +T+ K+ AHL GAKR Sbjct: 62 VSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKR 121 Query: 119 VIISAPS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTT 177 V+ISAP+ +D V VN + +I+S SCTTNCLAPLA + FGI G MTT Sbjct: 122 VLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMTT 181 Query: 178 VHAITATQKTVDGP-SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVP 236 +HA T+TQ +DGP G +R R A N IP STGAAKA+G VIPELNGKL G A RV Sbjct: 182 IHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRVG 241 Query: 237 TANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFD 296 + S+ +L L+K D++ +K+ +EG GY + ++VSSD T S FD Sbjct: 242 VVDGSLTELVAILDKKVTADEVNAAIKKHTEGNES--FGYNDDEIVSSDVIGTTFGSIFD 299 Query: 297 AGAGIALND---HFVKLISWYDNEFGYSNRVVDLMAHMAS 333 +D VK ++WYDNE+G++ ++V + A+ Sbjct: 300 PTQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFAT 339 >5LD5-A nrPDB Length = 358 Score = 244 bits (622), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 145/337 (43%), Positives = 196/337 (58%), Gaps = 24/337 (7%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKF---HGTV 60 VKV +NGFGRIGRL R F +IVAIND D + + +YDS+ G + H V Sbjct: 20 VKVAINGFGRIGRLAFRQMFGHEGSEIVAIND-LTDPKMLANLLKYDSSQGNYARNHSVV 78 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 E+ + ++G I I++E D + WG+ + V+E TG +T+ KA AH+ GAK+V+ Sbjct: 79 AGED-SITVDGKTIKIYKEADAHNLPWGELNVDVVLECTGFYTSKAKAQAHIDAGAKKVV 137 Query: 121 ISAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVH 179 ISAP+ D P V VNHE IIS ASCTTNCLAP+AK ++D I G+M+T+H Sbjct: 138 ISAPAGKDLPTIVYNVNHEILTKDDNIISAASCTTNCLAPMAKALNDFAPIQSGIMSTIH 197 Query: 180 AITATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFR--VP 236 A T Q +DGP K R R A NI+P STGAAKA+G VIPELNGKL G A R VP Sbjct: 198 AFTGDQMVLDGPHRKGDLRRARAAAINIVPNSTGAAKAIGLVIPELNGKLIGSAQRVPVP 257 Query: 237 TANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFD 296 T + +++ + +K D I +K AS+ GY E +VSSD T+ S FD Sbjct: 258 TGSTTLLFAVVKSDKEITVDSINAAMKAASD---PETFGYNEDPIVSSDIIGMTYGSLFD 314 Query: 297 A--------GAGIALNDHFVKLISWYDNEFGYSNRVV 325 A G G+ + V+++SWYDNE Y++++V Sbjct: 315 ATQTMVQDLGNGL----YQVEVVSWYDNENSYTSQMV 347 >5J9G-A nrPDB Length = 338 Score = 230 bits (586), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 139/341 (40%), Positives = 193/341 (56%), Gaps = 17/341 (4%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGK----VDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 VK+G+NGFGRIGRL R + G+ +++VAIND + ++ +YDSTHG F Sbjct: 3 VKIGINGFGRIGRLAFRRIMDLGEKSKDIEVVAIND-LTTPALLAHLLKYDSTHGTFDHE 61 Query: 60 VKAENGKLVINGNPITIFQERDPSKIKW-GDAGAEYVVESTGVFTTMEKAGAHLQGGAKR 118 V + +V++G ++ E I W + G ++V+E TG +T+ K+ AHL G KR Sbjct: 62 VSSTEDSIVVDGKKYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGVKR 121 Query: 119 VIISAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTT 177 V+ISAP+ D V VN + KI+S SCTTN LAP+ + FGI G MTT Sbjct: 122 VLISAPAGNDLKTIVYSVNQDTLTADDKIVSAGSCTTNSLAPMVNALQKEFGIEVGTMTT 181 Query: 178 VHAITATQKTVDGP--SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRV 235 +HA T+TQ +DGP G L A+ NIIP STGAAKA+G VIPELNGKL G A RV Sbjct: 182 IHAYTSTQMILDGPVRGGNLRAARAAAI-NIIPHSTGAAKAIGLVIPELNGKLNGHAQRV 240 Query: 236 PTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTF 295 P + SV +L L K D++ + +K+ E P Y + VVSSD T S F Sbjct: 241 PVPDGSVTELVSILGKNVTADEVNEAMKKY-ESPS---FEYEPNNVVSSDILGRTAGSIF 296 Query: 296 DAGAGI---ALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 D + A + VK ++WYDNE+ ++ ++V + H A+ Sbjct: 297 DPTQTMVTTAGDKQLVKTVAWYDNEYSFTCQMVRTLLHFAT 337 >3TZ6-A nrPDB Length = 344 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 32/200 (16%) Query: 49 YDSTHGKFHGTVKAENGKLVINGNPITI--FQERDPSKIKWGDAGAEYVVESTGVFTTME 106 + ++ +F + +++ KL G I + + DPS G + + S G + M Sbjct: 26 FPASAVRFFASARSQGRKLAFRGQEIEVEDAETADPS-------GLDIALFSAG--SAMS 76 Query: 107 KAGAHLQGGAKRVIISAPSA-----DAPMFVMGVNHEK--YDNSLKIISNASCTTNCLAP 159 K A A +I SA D P+ V VN E+ + II+N +CTT P Sbjct: 77 KVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRRPKGIIANPNCTTMAAMP 136 Query: 160 LAKVIHDNFGIVEGLMTTVHAITAT-----------QKTVDGPSGKLWRDGRGALQNIIP 208 + KV+HD +V ++++ A++ + + V G + +L DG GAL+ P Sbjct: 137 VLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGGAEQLVYDG-GALE-FPP 194 Query: 209 ASTGAAKAVGKVIPELNGKL 228 +T A V+P L G L Sbjct: 195 PNTYVAPIAFNVVP-LAGSL 213 >2YV3-A nrPDB Length = 331 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 38/161 (23%), Positives = 63/161 (39%), Gaps = 24/161 (14%) Query: 129 PMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA-------- 180 P+ V VN EK II+N +CTT LA +H F ++ T A Sbjct: 102 PLVVPEVNREKIFQHRGIIANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAKA 161 Query: 181 ----ITATQKTVDGPSGKLWRDGRGALQNIIP-----ASTGAAKAVGKVIPELNG----- 226 +T T + + G + K N+IP G + KV+ E + Sbjct: 162 MEELLTETHRFLHGEAPKAEAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDD 221 Query: 227 --KLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQA 265 +++ A RVPT ++ +P + ++V+K+A Sbjct: 222 TIRISATAVRVPTLRAHAEAVSVEFARPVTPEAAREVLKEA 262 >2CZC-A nrPDB Length = 334 Score = 33.1 bits (74), Expect = 0.15, Method: Compositional matrix adjust. Identities = 66/276 (23%), Positives = 102/276 (36%), Gaps = 63/276 (22%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFID--------LNYMVY------MFQ 48 KVKVGVNG+G IG+ V A ++++ I D L VY + + Sbjct: 2 KVKVGVNGYGTIGKRVAYAVTKQDDMELIGITKTKPDFEAYRAKELGIPVYAASEEFIPR 61 Query: 49 YDSTHGKFHGTVK--AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTME 106 ++ + GT+ E ++++ P I + P E Sbjct: 62 FEKEGFEVAGTLNDLLEKVDIIVDATPGGIGAKNKP---------------------LYE 100 Query: 107 KAG--AHLQGGAKRVIISAPSADAPMFVMGVNHEKY--DNSLKIISNASCTTNCLAPLAK 162 KAG A QGG K + FV N+E N ++++ SC T L Sbjct: 101 KAGVKAIFQGGEKADVAEVS------FVAQANYEAALGKNYVRVV---SCNTTGLVRTLS 151 Query: 163 VIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIP 222 I + V +M + T GP A++ + + V VIP Sbjct: 152 AIREYADYVYAVM--IRRAADPNDTKRGPI--------NAIKPTVEVPSHHGPDVQTVIP 201 Query: 223 ELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDI 258 +N + MAF VPT + V + L+KP DD+ Sbjct: 202 -IN--IETMAFVVPTTLMHVHSVMVELKKPLTKDDV 234 >3HSK-A nrPDB Length = 381 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 43/172 (25%), Positives = 69/172 (40%), Gaps = 40/172 (23%) Query: 127 DAPMFVMGVNHEKYD---NSLK------------IISNASCTTNCLAPLAKVIHDNFGIV 171 D P+ V VN E D N +K II ++C+T L K + + FG + Sbjct: 132 DVPLVVPIVNPEHIDVVENKVKQAVSKGGKKPGFIICISNCSTAGLVAPLKPLVEKFGPI 191 Query: 172 EGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTG--------AAKAVGKV--- 220 + L TT T + + G G L NI+P +G K +G V Sbjct: 192 DALTTT------TLQAISGAGFSPGVSGMDILDNIVPYISGEEDKLEWETKKILGGVNAE 245 Query: 221 ------IPELNGKLTGMAFRVPTANVSVVDLTCRL-EKPA-KYDDIKKVVKQ 264 IPE K++ RVP + ++ R +PA +D+K+ +++ Sbjct: 246 GTEFVPIPESEMKVSAQCNRVPVIDGHTECISLRFANRPAPSVEDVKQCLRE 297 >3SDS-A nrPDB Length = 353 Score = 31.2 bits (69), Expect = 0.67, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 14/67 (20%) Query: 129 PMFV------MGVNHEKYDNSLKIISNASCTTNCLAP------LAKVIHDNFGIVEGLMT 176 PMF+ +GVN YD S+ I S SC + P LAK H + ++ L Sbjct: 95 PMFLGKDDIQLGVNESLYDTSVVISSMVSCIVARVGPHSDIANLAK--HSSVPVINALCD 152 Query: 177 TVHAITA 183 T H + A Sbjct: 153 TFHPLQA 159 >1BSF-A nrPDB Length = 278 Score = 31.2 bits (69), Expect = 0.74, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 44 VYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQ 78 VY Q+ HGK H V+A + + + GNP +FQ Sbjct: 161 VYETQWYVKHGKLHLEVRARSNDMAL-GNPFNVFQ 194 >1YS4-A nrPDB Length = 354 Score = 30.8 bits (68), Expect = 0.78, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 93 EYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASC 152 E+ E +F+ A A+ ++I +AD + ++ + EK II+N +C Sbjct: 102 EFAKEGKLIFSN---ASAYRMEEDVPLVIPEVNADH-LELIEIQREKRGWDGAIITNPNC 157 Query: 153 TTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 +T C K I D FG+ + T+ A++ Sbjct: 158 STICAVITLKPIMDKFGLEAVFIATMQAVS 187 >3L2D-A nrPDB Length = 390 Score = 30.8 bits (68), Expect = 0.91, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 30/113 (26%) Query: 123 APSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAP---------LAKVIHDNFGIVEG 173 AP D V GV +KY S +I S CL P + KV+ D G ++G Sbjct: 119 APDLDHNKLVGGVFEDKYVKSCRIRCGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKG 178 Query: 174 -------LMTTVHAITATQKTVD-----GPSGKL---------WRDGRGALQN 205 +TT++ Q D P+G L W DGRG N Sbjct: 179 DLAGKYYPLTTMNEKDQEQLIEDHFLFEKPTGALLTTSGCARDWPDGRGIWHN 231 >1IPK-A nrPDB Length = 416 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSD 289 N+ ++ L + KP +YDD QA + L+G H ++ + F+S+ Sbjct: 119 NLKIIKLAIPVNKPGRYDDFFLSSTQAQQSYLQGF----SHNILETSFHSE 165 >1C8B-A nrPDB Length = 371 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 18/132 (13%) Query: 83 SKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDN 142 S ++ + GAE + + G + T+E G Q K+ A +F +N + Sbjct: 53 SMVEITEEGAEAIGKKKGRYVTLESVGIREQDTEKQ-----EEAMEEVFAKELNF--FIK 105 Query: 143 SLKIISNASCTTNCLAPLAKVIHDNFG--IVEGLMTTVHAITATQKTVDGPSGKLWRDGR 200 SL I +ASC L L+ V D G V+ L+ T H ++V +DG Sbjct: 106 SLNIPDDASCLVVGLGNLS-VTPDALGPKAVDNLLITRHLFELQPESV--------QDGF 156 Query: 201 GALQNIIPASTG 212 + I+P G Sbjct: 157 RPVSAIVPGVMG 168 >3LS0-A nrPDB Length = 133 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQ + GP G+L RD G +++P AK + K E+ G L + N S Sbjct: 55 TQTYIHGPLGQLRRDMLGLASSLLPKDQDKAKTLAK---EVFGHLERLDAAAKDRNGSQA 111 Query: 244 DLTCRLEKPAKYDDIKKVVKQAS 266 + + E A +D ++ QAS Sbjct: 112 KIQYQ-EALADFDSFLNLLPQAS 133 >5W64-O nrPDB Length = 894 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 6/64 (9%) Query: 247 CRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVV-----SSDFNSDTH-SSTFDAGAG 300 RLEKP+ ++ I+ + ++ GP + I+ + + S++FN D+ S+ F+ Sbjct: 745 ARLEKPSLFEPIQNEISRSLSGPYQDIISSWDMDDINEEDESNEFNFDSQFSAPFNGRPP 804 Query: 301 IALN 304 LN Sbjct: 805 FNLN 808 >5N61-P nrPDB Length = 894 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 6/64 (9%) Query: 247 CRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVV-----SSDFNSDTH-SSTFDAGAG 300 RLEKP+ ++ I+ + ++ GP + I+ + + S++FN D+ S+ F+ Sbjct: 745 ARLEKPSLFEPIQNEISRSLSGPYQDIISSWDMDDINEEDESNEFNFDSQFSAPFNGRPP 804 Query: 301 IALN 304 LN Sbjct: 805 FNLN 808 >2YYY-A nrPDB Length = 343 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 56/274 (20%), Positives = 99/274 (36%), Gaps = 42/274 (15%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLN--------YMVYMFQYDSTHGKF 56 KV +NG+G IG+ V A ++++ + D Y +++ D+ K Sbjct: 4 KVLINGYGSIGKRVADAVSMQDDMEVIGVTKTKPDFEARLAVEKGYKLFVAIPDNERVKL 63 Query: 57 HGTVKAENGKLVINGNPITIFQERD------PSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 E+ + + G + I ++ D P KI G E + + K A Sbjct: 64 F-----EDAGIPVEGTILDIIEDADIVVDGAPKKI--GKQNLENIYKP-------HKVKA 109 Query: 111 HLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGI 170 LQGG K + D + N + ++++S C T L + I+ I Sbjct: 110 ILQGGEK----AKDVEDNFNALWSYNRCYGKDYVRVVS---CNTTGLCRILYAINSIADI 162 Query: 171 VEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTG 230 + + V GP + N + + V V+PE GK+ Sbjct: 163 KKARIVLVRRAADPNDDKTGPVNAI-------TPNPVTVPSHHGPDVVSVVPEFEGKILT 215 Query: 231 MAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQ 264 A VPT + + L ++ DDI + +K+ Sbjct: 216 SAVIVPTTLMHMHTLMVEVDGDVSRDDILEAIKK 249 >3WYB-A nrPDB Length = 334 Score = 28.1 bits (61), Expect = 5.3, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 22/33 (66%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAI 33 M K+++G+ G+G +GR V A + +++VA+ Sbjct: 1 MSKIRIGIVGYGNLGRGVEAAIQQNPDMELVAV 33 >5W65-O nrPDB Length = 894 Score = 28.1 bits (61), Expect = 5.4, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 6/64 (9%) Query: 247 CRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVV-----SSDFNSDTH-SSTFDAGAG 300 RLEKP+ ++ I+ + ++ GP + I+ + + S++FN D+ S+ F+ Sbjct: 745 ARLEKPSLFEPIQNEISRSLSGPYQDIISSWDMDDINEEDESNEFNFDSQFSAPFNGRPP 804 Query: 301 IALN 304 LN Sbjct: 805 FNLN 808 >2IV0-A nrPDB Length = 412 Score = 28.1 bits (61), Expect = 5.6, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 8/57 (14%) Query: 47 FQYDSTHGKFHGT-VKAENGKLVINGNPITIFQERD-------PSKIKWGDAGAEYV 95 QY+ +G ++ ENGKL++ NPI + E D P+ I+ DA A+ + Sbjct: 1 MQYEKVKPPENGEKIRYENGKLIVPDNPIIPYFEGDGIGKDVVPAAIRVLDAAADKI 57 >4KKJ-A nrPDB Length = 467 Score = 27.7 bits (60), Expect = 6.5, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 9/93 (9%) Query: 212 GAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLK 271 A+ V PE G F V T ++V+ LTC K I +K A EG LK Sbjct: 162 STAEVVNHFTPENKNYYFGSQFSVDTGAMAVLALTC-----VKKSLINGQIK-ADEGSLK 215 Query: 272 GILGYTE---HQVVSSDFNSDTHSSTFDAGAGI 301 I YT+ +++S + +TF G + Sbjct: 216 NISIYTKSLVEKILSEKKENGLIGNTFSTGEAM 248 >2R00-A nrPDB Length = 336 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 127 DAPMFVMGVNHE---KYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 D P+ V VN E ++ N II+N +C+T + K I+D GI +TT +++ Sbjct: 104 DIPLVVPEVNPEAIAEFRNR-NIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSG 162 Query: 184 TQKT-VDGPSGKLWRDGRGALQNIIPASTG--AAKAVGKVIPELN 225 K +D +G+ L N PA T + + IP+++ Sbjct: 163 AGKAGIDELAGQT-----AKLLNGYPAETNTFSQQIAFNCIPQID 202 >4FCY-A nrPDB Length = 529 Score = 27.3 bits (59), Expect = 8.8, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 172 EGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNII 207 EG +H I A Q+TV+ W +G G L N+ Sbjct: 165 EGEHALMHLIPAQQRTVEHLDAMQWINGDGYLHNVF 200 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1ZNQ-O nrPDB 587 e-168 3GPD-R nrPDB 569 e-163 5C7I-O nrPDB 565 e-162 2VYN-D nrPDB 560 e-160 3H9E-O nrPDB 560 e-160 4K9D-A nrPDB 556 e-159 1CRW-G nrPDB 552 e-158 6NLX-A nrPDB 550 e-157 3PYM-A nrPDB 549 e-157 5UR0-A nrPDB 549 e-157 2B4T-O nrPDB 549 e-157 3E5R-O nrPDB 545 e-156 4Z0H-O nrPDB 545 e-155 6DFZ-A nrPDB 544 e-155 4P8R-A nrPDB 543 e-155 4MVJ-P nrPDB 543 e-155 1VSU-A nrPDB 541 e-154 2I5P-O nrPDB 536 e-153 4LSM-A nrPDB 533 e-152 1NPT-O nrPDB 524 e-149 1HDG-O nrPDB 519 e-148 3STH-A nrPDB 518 e-147 2EP7-A nrPDB 510 e-145 6OK4-A nrPDB 510 e-145 1ML3-A nrPDB 504 e-143 3L0D-A nrPDB 504 e-143 4BOY-A nrPDB 502 e-142 3GNQ-A nrPDB 500 e-142 5VMT-A nrPDB 500 e-142 3DOC-A nrPDB 498 e-141 2X0N-A nrPDB 497 e-141 5M6D-A nrPDB 497 e-141 1I33-A nrPDB 494 e-140 3HJA-A nrPDB 487 e-138 6FZI-A nrPDB 487 e-138 6FZH-A nrPDB 487 e-138 5JY6-A nrPDB 483 e-137 3VAZ-P nrPDB 482 e-137 1VC2-A nrPDB 478 e-135 1OBF-O nrPDB 478 e-135 1CER-O nrPDB 476 e-135 1JN0-O nrPDB 473 e-134 4DIB-A nrPDB 466 e-132 2DUU-A nrPDB 466 e-132 3B1K-A nrPDB 462 e-131 5LD5-A nrPDB 460 e-130 2PKQ-O nrPDB 458 e-129 6IQV-A nrPDB 457 e-129 3RVD-A nrPDB 452 e-128 2XF8-A nrPDB 450 e-127 5J9G-A nrPDB 443 e-125 3TZ6-A nrPDB 154 5e-38 Sequences not found previously or not previously below threshold: 2YV3-A nrPDB 81 6e-16 2R00-A nrPDB 76 2e-14 3PWS-A nrPDB 67 1e-11 1YS4-A nrPDB 53 2e-07 2CZC-A nrPDB 47 1e-05 1CF2-P nrPDB 45 6e-05 3HSK-A nrPDB 40 0.001 2EP5-A nrPDB 40 0.002 2YYY-A nrPDB 39 0.003 3WYB-A nrPDB 39 0.003 6C8W-A nrPDB 38 0.006 3BIO-A nrPDB 36 0.021 5CEF-A nrPDB 36 0.026 2DC1-A nrPDB 34 0.063 3AOE-A nrPDB 34 0.067 3WGO-A nrPDB 34 0.090 3DAP-A nrPDB 34 0.12 4ZHS-D nrPDB 34 0.13 3WBB-A nrPDB 33 0.21 3MH6-A nrPDB 32 0.35 1B7G-O nrPDB 32 0.44 5VM2-A nrPDB 31 0.53 3GIX-A nrPDB 31 0.59 3DC2-A nrPDB 30 1.2 4F3Y-A nrPDB 30 1.5 3L9X-A nrPDB 30 1.7 4WOJ-A nrPDB 30 1.8 6IGZ-L nrPDB 30 1.9 3EUW-A nrPDB 29 2.1 3EC7-A nrPDB 29 2.3 5G1T-A nrPDB 29 2.5 1W9M-A nrPDB 29 2.7 4XEB-A nrPDB 29 3.1 3PAJ-A nrPDB 29 3.2 5AOV-A nrPDB 29 3.7 6DLD-B nrPDB 29 3.9 1IWP-B nrPDB 29 4.0 1XDW-A nrPDB 29 4.2 4BI9-A nrPDB 28 4.9 6G1M-A nrPDB 28 4.9 3M6I-A nrPDB 28 5.1 2HAE-A nrPDB 28 5.4 3L6G-A nrPDB 28 6.0 1B26-A nrPDB 28 6.9 5J5Z-A nrPDB 27 7.7 4DPM-A nrPDB 27 7.8 1I74-A nrPDB 27 7.9 2IIR-A nrPDB 27 9.4 5CXX-A nrPDB 27 9.9 >1ZNQ-O nrPDB Length = 338 Score = 587 bits (1515), Expect = e-168, Method: Composition-based stats. Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV Sbjct: 4 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 63 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI Sbjct: 64 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 123 Query: 121 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA Sbjct: 124 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 183 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV Sbjct: 184 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 243 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG Sbjct: 244 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 303 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE Sbjct: 304 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 338 >3GPD-R nrPDB Length = 334 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 300/334 (89%), Positives = 314/334 (94%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 GKVKVGV+GFGRIGRLVTRAAFNSGKVDIVAINDPFIDL+YMVYMFQYDSTHGKFHGTVK Sbjct: 1 GKVKVGVDGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLHYMVYMFQYDSTHGKFHGTVK 60 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 AE+GKLVI+G ITIFQERDP IKWGDAG YVVESTGVFTTMEKAGAHL+GGAKR++I Sbjct: 61 AEDGKLVIDGKAITIFQERDPENIKWGDAGTAYVVESTGVFTTMEKAGAHLKGGAKRIVI 120 Query: 122 SAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 SAPSADAPMFVMGVNH KY NSLKIISNASCTTNCLAPLAKVIHD+FGIVEGLMTTVHAI Sbjct: 121 SAPSADAPMFVMGVNHFKYANSLKIISNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAI 180 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQKTVD PSGKLWR GRGA QN+IPASTGAAKAVGKVIPEL+GKLTGMAFRVPTANVS Sbjct: 181 TATQKTVDSPSGKLWRGGRGAAQNLIPASTGAAKAVGKVIPELDGKLTGMAFRVPTANVS 240 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 V+DLTCRLEKPAKYDDIKKVVK+ASEGPLKGILGYTE +VVS DFN HSS FDAGAGI Sbjct: 241 VLDLTCRLEKPAKYDDIKKVVKEASEGPLKGILGYTEDEVVSDDFNGSNHSSIFDAGAGI 300 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 LND FVKL+SWYDNEFGYS RVVDLMAHMASKE Sbjct: 301 ELNDTFVKLVSWYDNEFGYSERVVDLMAHMASKE 334 >5C7I-O nrPDB Length = 333 Score = 565 bits (1457), Expect = e-162, Method: Composition-based stats. Identities = 228/334 (68%), Positives = 272/334 (81%), Gaps = 2/334 (0%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 ++ VG+NGFGRIGRLV R G + +VA+NDPFID YMVYMF+YDSTHG++ G V+ Sbjct: 1 ELTVGINGFGRIGRLVLRVCMEKG-IRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGNVEH 59 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 +NG+LV++ I +Q +DP +I W G YVVE TGV+ ++E A AH+ GA+RV+++ Sbjct: 60 KNGQLVVDNLEINTYQCKDPKEIPWSSIGNPYVVECTGVYLSIEAASAHISSGARRVVVT 119 Query: 123 APSADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 APS DAPMFVMGVN + Y+ S+ I+SNASCTTNCLAPLAKVIH+NFGIVEGLMTTVH+ Sbjct: 120 APSPDAPMFVMGVNEKDYNPGSMTIVSNASCTTNCLAPLAKVIHENFGIVEGLMTTVHSY 179 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGKVIPEL GKLTGMAFRVPT NVS Sbjct: 180 TATQKTVDGPSKKDWRGGRGAHQNIIPSSTGAAKAVGKVIPELKGKLTGMAFRVPTPNVS 239 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLTCRL KPA Y I + VK A++GPL GIL YTE QVVS+DFN + HSS FDA AGI Sbjct: 240 VVDLTCRLAKPASYSAITEAVKAAAKGPLAGILAYTEDQVVSTDFNGNPHSSIFDAKAGI 299 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 ALND+FVKL++WYDNE+GYSNRVVDL+ +M S+E Sbjct: 300 ALNDNFVKLVAWYDNEYGYSNRVVDLLRYMFSRE 333 >2VYN-D nrPDB Length = 334 Score = 560 bits (1444), Expect = e-160, Method: Composition-based stats. Identities = 231/333 (69%), Positives = 275/333 (82%), Gaps = 2/333 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRLV R G V +VA+NDPFID YMVYMF+YDSTHG++ GTV+ + Sbjct: 2 VKVGINGFGRIGRLVLRVCMEKG-VRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGTVEHK 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 NG+LV++ I +FQ ++P +I W G YVVE+TGV+ ++E A H+ GA+RVI++A Sbjct: 61 NGRLVVDNLEINVFQCKEPKEIPWSSVGNPYVVEATGVYLSIEAASGHISSGARRVIVTA 120 Query: 124 PSADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PS DAPM VMGVN + Y+ S+ ++SNASCTTNCLAPLAKVIH+ FGIVEGLMTTVHA T Sbjct: 121 PSPDAPMLVMGVNEKDYNPGSMTVVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHAYT 180 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGKVIPELNGKLTGMAFRVPT NVSV Sbjct: 181 ATQKTVDGPSKKDWRGGRGAHQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV 240 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLTCRL +PA Y IK+ VK A++GP+ GIL YTE QVVS+DFN D+HSS FDA AGIA Sbjct: 241 VDLTCRLAQPASYTAIKEAVKAAAKGPMAGILAYTEDQVVSTDFNGDSHSSIFDAKAGIA 300 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 LND+FVKL+SWYDNE+GYS+RVVDL+ +M S+E Sbjct: 301 LNDNFVKLVSWYDNEYGYSHRVVDLLRYMFSRE 333 >3H9E-O nrPDB Length = 346 Score = 560 bits (1444), Expect = e-160, Method: Composition-based stats. Identities = 228/334 (68%), Positives = 276/334 (82%), Gaps = 2/334 (0%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 ++ VG+NGFGRIGRLV RA G V +VA+NDPFID YMVYMF+YDSTHG++ G+V+ Sbjct: 7 ELTVGINGFGRIGRLVLRACMEKG-VKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEF 65 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 NG+LV++ + I+++Q ++P +I W G+ YVVESTGV+ +++ A H+ GA+RV+IS Sbjct: 66 RNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVIS 125 Query: 123 APSADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 APS DAPMFVMGVN Y+ S+ I+SNASCTTNCLAPLAKVIH+ FGIVEGLMTTVH+ Sbjct: 126 APSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSY 185 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQKTVDGPS K WRDGRGA QNIIPASTGAAKAV KVIPEL GKLTGMAFRVPT +VS Sbjct: 186 TATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVS 245 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLTCRL +PA Y IK+ VK A++GP+ GIL YTE +VVS+DF DTHSS FDA AGI Sbjct: 246 VVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGI 305 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 ALND+FVKLISWYDNE+GYS+RVVDL+ +M S++ Sbjct: 306 ALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRD 339 >4K9D-A nrPDB Length = 347 Score = 556 bits (1434), Expect = e-159, Method: Composition-based stats. Identities = 251/339 (74%), Positives = 291/339 (85%), Gaps = 5/339 (1%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 M K KVG+NGFGRIGRLV RAA VD+VA+NDPFI+++YMVYMF+YDSTHG+F G+V Sbjct: 9 MSKPKVGINGFGRIGRLVLRAAVEKDTVDVVAVNDPFINIDYMVYMFKYDSTHGRFKGSV 68 Query: 61 KAENGKLVI-NGNP---ITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGA 116 AE GKL++ NG I++ +DP++I WG GAEYVVESTGVFTT +KA AHL+GGA Sbjct: 69 SAEGGKLIVTNGKTTHHISVHNSKDPAEIPWGVDGAEYVVESTGVFTTTDKASAHLKGGA 128 Query: 117 KRVIISAPSADAPMFVMGVNHEKYDNSL-KIISNASCTTNCLAPLAKVIHDNFGIVEGLM 175 K+VIISAPSADAPMFVMGVN++ YD + IISNASCTTNCLAPLAKVIHD FGI+EGLM Sbjct: 129 KKVIISAPSADAPMFVMGVNNDTYDKANNHIISNASCTTNCLAPLAKVIHDKFGIIEGLM 188 Query: 176 TTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRV 235 TTVHA TATQKTVDGPSGKLWRDGRGA QNIIPASTGAAKAVGKVIP+LNGKLTGMAFRV Sbjct: 189 TTVHATTATQKTVDGPSGKLWRDGRGAGQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRV 248 Query: 236 PTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTF 295 PT +VSVVDLTCRL+K A D+IK VK+A+ GP+KGIL YTE QVVS+DF DTHSS F Sbjct: 249 PTPDVSVVDLTCRLQKGATMDEIKAAVKEAANGPMKGILEYTEDQVVSTDFTGDTHSSIF 308 Query: 296 DAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 DA A I+LN +FVKLI+WYDNE+GYSNRVVDL++++AS+ Sbjct: 309 DALACISLNPNFVKLIAWYDNEYGYSNRVVDLISYIASR 347 >1CRW-G nrPDB Length = 333 Score = 552 bits (1424), Expect = e-158, Method: Composition-based stats. Identities = 239/331 (72%), Positives = 270/331 (81%), Gaps = 1/331 (0%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 K+G+NGFGRIGRLV RAA G +VA+NDPFI L YMVYMF+YDSTHG F G VKAE+ Sbjct: 2 KIGINGFGRIGRLVLRAALEMGA-QVVAVNDPFIALEYMVYMFKYDSTHGMFKGEVKAED 60 Query: 65 GKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAP 124 G LV++G IT+F E P I W AGAEY+VESTGVFTT+EKA AH +GGAK+VIISAP Sbjct: 61 GALVVDGKKITVFNEMKPENIPWSKAGAEYIVESTGVFTTIEKASAHFKGGAKKVIISAP 120 Query: 125 SADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITAT 184 SADAPMFV GVN EKY +K++SNASCTTNCLAP+AKV+H+NF IVEGLMTTVHA+TAT Sbjct: 121 SADAPMFVCGVNLEKYSKDMKVVSNASCTTNCLAPVAKVLHENFEIVEGLMTTVHAVTAT 180 Query: 185 QKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVD 244 QKTVDGPS K WR GRGA QNIIP+STGAAKAVGKVIPEL+GKLTGMAFRVPT NVSVVD Sbjct: 181 QKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPELDGKLTGMAFRVPTPNVSVVD 240 Query: 245 LTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALN 304 LT RL K YDDIK +K ASEGPL+G+LGYTE VVS DF D SS FDA AGI L+ Sbjct: 241 LTVRLGKECSYDDIKAAMKAASEGPLQGVLGYTEDDVVSCDFTGDNRSSIFDAKAGIQLS 300 Query: 305 DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 FVK++SWYDNEFGYS RV+DL+ HM + Sbjct: 301 KTFVKVVSWYDNEFGYSQRVIDLIKHMQKVD 331 >6NLX-A nrPDB Length = 341 Score = 550 bits (1418), Expect = e-157, Method: Composition-based stats. Identities = 211/326 (64%), Positives = 258/326 (79%), Gaps = 2/326 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRLV RA+ V++VAIND + +YM+YM +YDS HGKF+G ++ Sbjct: 10 VKVGINGFGRIGRLVFRASLERTDVEVVAINDIMMTPDYMIYMIKYDSVHGKFNGKLEYT 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + +NG I +F ER+P K+ WG G EYVVESTGVFT ++ A HL+GGAKRV+ISA Sbjct: 70 ENSIKVNGREIHVFCEREPEKLPWGQYGVEYVVESTGVFTKLDTASKHLKGGAKRVVISA 129 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 P+ D P FVMGVN+ ++ + +I+NASCTTNCLAP+A V+H+NFGIVEGLMTTVHA+TA Sbjct: 130 PA-DTPTFVMGVNNHEFKPEMTVINNASCTTNCLAPIAAVLHENFGIVEGLMTTVHALTA 188 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQ TVD PS K WR GR A NIIP+STGAAKAVG VIP LNGKLTGMAFRVPTA+VSVV Sbjct: 189 TQPTVDAPSKKDWRGGRAAGYNIIPSSTGAAKAVGLVIPSLNGKLTGMAFRVPTADVSVV 248 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGP-LKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 DLTCRLEKPA I + +K+ASE KGIL YTE +VVSSDF D+ SST+D+ A I+ Sbjct: 249 DLTCRLEKPATKKQIDEAMKKASESERFKGILKYTEEEVVSSDFIHDSASSTYDSKASIS 308 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLM 328 LNDHFVK+++WYDNE+GYSNRV+DL+ Sbjct: 309 LNDHFVKVVAWYDNEWGYSNRVLDLI 334 >3PYM-A nrPDB Length = 332 Score = 549 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 214/330 (64%), Positives = 262/330 (79%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 V+V +NGFGRIGRLV R A + V++VA+NDPFI +Y YMF+YDSTHG++ G V + Sbjct: 2 VRVAINGFGRIGRLVMRIALSRPNVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHD 61 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + ++++G I +QERDP+ + WG + + ++STGVF ++ A H+ GAK+V+I+A Sbjct: 62 DKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITA 121 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 PS+ APMFVMGVN EKY + LKI+SNASCTTNCLAPLAKVI+D FGI EGLMTTVH++TA Sbjct: 122 PSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTA 181 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+PEL GKLTGMAFRVPT +VSVV Sbjct: 182 TQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVV 241 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIAL 303 DLT +L K YD+IKKVVK A+EG LKG+LGYTE VVSSDF D+HSS FDA AGI L Sbjct: 242 DLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQL 301 Query: 304 NDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + FVKL+SWYDNE+GYS RVVDL+ H+A Sbjct: 302 SPKFVKLVSWYDNEYGYSTRVVDLVEHVAK 331 >5UR0-A nrPDB Length = 349 Score = 549 bits (1414), Expect = e-157, Method: Composition-based stats. Identities = 205/331 (61%), Positives = 254/331 (76%), Gaps = 2/331 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VK+G+NGFGRIGRLV RA+ V++VAIND + YM+YM +YD+ HGKFHG ++ Sbjct: 18 VKIGINGFGRIGRLVFRASLERTDVEVVAINDIMMTPEYMIYMIKYDTVHGKFHGKLEHT 77 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +++NG I + ERDP ++ WG EYVVESTG+FT ++ A HL+GGAKRV+ISA Sbjct: 78 EKSIIVNGREIHVLCERDPEQLPWGQHNVEYVVESTGIFTKLDSAAKHLKGGAKRVVISA 137 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 P+ D P FVMGVN+ +Y + +I+NASCTTNCLAP+A V+H+NFGIVEGLMTTVHA+TA Sbjct: 138 PA-DTPTFVMGVNNHEYKPEMTVINNASCTTNCLAPIAAVLHENFGIVEGLMTTVHAVTA 196 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQ TVD PS K WR GR A NIIP+STGAAKAVG VIP LNGKLTGMAFRVPT +VSVV Sbjct: 197 TQPTVDAPSRKDWRGGRAAGYNIIPSSTGAAKAVGLVIPSLNGKLTGMAFRVPTVDVSVV 256 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGP-LKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 DLTCRLEKPA I + +K ASE KGIL +T+ +VVSSDF D+ SST+D+ A I Sbjct: 257 DLTCRLEKPATKKQIDEAMKAASESERFKGILKFTDEEVVSSDFVHDSASSTYDSKASIC 316 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 LN+HFVK+++WYDNE+GYSNRV+DL+ A Sbjct: 317 LNEHFVKVVAWYDNEWGYSNRVLDLIKSTAK 347 >2B4T-O nrPDB Length = 345 Score = 549 bits (1414), Expect = e-157, Method: Composition-based stats. Identities = 214/332 (64%), Positives = 260/332 (78%), Gaps = 3/332 (0%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 K+G+NGFGRIGRLV RAAF +++VAINDPF+DLN++ Y+ +YDS HG+F V + Sbjct: 13 KLGINGFGRIGRLVFRAAFGRKDIEVVAINDPFMDLNHLCYLLKYDSVHGQFPCEVTHAD 72 Query: 65 GKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAP 124 G L+I +++F E+DPS+I WG + V ESTGVF T E A +HL+GGAK+VI+SAP Sbjct: 73 GFLLIGEKKVSVFAEKDPSQIPWGKCQVDVVCESTGVFLTKELASSHLKGGAKKVIMSAP 132 Query: 125 SAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 D P++VMG+NH +YD I+SNASCTTNCLAPLAKVI+D FGIVEGLMTTVHA TA Sbjct: 133 PKDDTPIYVMGINHHQYDTKQLIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHASTA 192 Query: 184 TQKTVDGPSG--KLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q VDGPS K WR GR AL NIIPASTGAAKAVGKV+PELNGKLTG+AFRVP VS Sbjct: 193 NQLVVDGPSKGGKDWRAGRCALSNIIPASTGAAKAVGKVLPELNGKLTGVAFRVPIGTVS 252 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDL CRL+KPAKY+++ +K+A+EGPLKGILGYTE +VVS DF D SS FD AG+ Sbjct: 253 VVDLVCRLQKPAKYEEVALEIKKAAEGPLKGILGYTEDEVVSQDFVHDNRSSIFDMKAGL 312 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 ALND+F KL+SWYDNE+GYSNRV+DL H+ + Sbjct: 313 ALNDNFFKLVSWYDNEWGYSNRVLDLAVHITT 344 >3E5R-O nrPDB Length = 337 Score = 545 bits (1406), Expect = e-156, Method: Composition-based stats. Identities = 230/337 (68%), Positives = 278/337 (82%), Gaps = 2/337 (0%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT- 59 MGK+K+G+NGFGRIGRLV R A S V++VA+NDPFI +YM YMF+YD+ HG++ + Sbjct: 1 MGKIKIGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQWKHSD 60 Query: 60 VKAENGK-LVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKR 118 +K ++ K L++ P+T+F R+P +I W +AGAEYVVESTGVFT EKA AHL+GGAK+ Sbjct: 61 IKIKDSKTLLLGEKPVTVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKAAAHLKGGAKK 120 Query: 119 VIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 V+ISAPS DAPMFV GVN +KY + + I+SNASCTTNCLAPLAKVIHDNFGI+EGLMTTV Sbjct: 121 VVISAPSKDAPMFVCGVNEDKYTSDIDIVSNASCTTNCLAPLAKVIHDNFGIIEGLMTTV 180 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 HAITATQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+P+LNGKLTGM+FRVPT Sbjct: 181 HAITATQKTVDGPSSKDWRGGRAASFNIIPSSTGAAKAVGKVLPDLNGKLTGMSFRVPTV 240 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 +VSVVDLT R+EK A YD IK +K ASEG LKGI+GY E +VS+DF D+ SS FDA Sbjct: 241 DVSVVDLTVRIEKAASYDAIKSAIKSASEGKLKGIIGYVEEDLVSTDFVGDSRSSIFDAK 300 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 AGIALND+FVKL++WYDNE+GYSNRV+DL+ HMA + Sbjct: 301 AGIALNDNFVKLVAWYDNEWGYSNRVIDLIRHMAKTQ 337 >4Z0H-O nrPDB Length = 334 Score = 545 bits (1404), Expect = e-155, Method: Composition-based stats. Identities = 225/333 (67%), Positives = 268/333 (80%), Gaps = 2/333 (0%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHG-TVK 61 K+++G+NGFGRIGRLV R V++VA+NDPFI YM YMF+YDS HG++ +K Sbjct: 1 KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELK 60 Query: 62 AENGK-LVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 ++ K L+ P+T+F R+P I W +AGA+YVVESTGVFT +KA AHL+GGAK+V+ Sbjct: 61 IKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVV 120 Query: 121 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 ISAPS DAPMFV+GVN +Y + L I+SNASCTTNCLAPLAKVI+D FGIVEGLMTTVH+ Sbjct: 121 ISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHS 180 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 ITATQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+P LNGKLTGM+FRVPT +V Sbjct: 181 ITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDV 240 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLT RLEK A YD+IKK +K+ SEG LKGILGYTE VVS+DF D SS FDA AG Sbjct: 241 SVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAG 300 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 IAL+D FVKL+SWYDNE+GYS+RVVDL+ HM+ Sbjct: 301 IALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSK 333 >6DFZ-A nrPDB Length = 332 Score = 544 bits (1401), Expect = e-155, Method: Composition-based stats. Identities = 249/332 (75%), Positives = 288/332 (86%), Gaps = 1/332 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRLV RA+ +V +VA+NDPFIDL YM YMF+YDSTHG+F GT + + Sbjct: 1 VKVGINGFGRIGRLVMRASLEHPEVQVVAVNDPFIDLEYMEYMFKYDSTHGRFKGTTEVK 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +GKLVINGNPI+++ +DP+ I W +AGA++VVESTGVFTT EKA AHL GGAK+VIISA Sbjct: 61 DGKLVINGNPISVYALKDPAAIPWKEAGADFVVESTGVFTTTEKASAHLHGGAKKVIISA 120 Query: 124 PSADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PSADAPMFVMGVN + YD ++ ++SNASCTTNCLAPLAKVI+DNFGI EGLMTT+HA T Sbjct: 121 PSADAPMFVMGVNEKTYDAATMNVVSNASCTTNCLAPLAKVINDNFGIEEGLMTTIHAYT 180 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPSGK WRDGRGA QN+IPA+TGAAKAVGKVIPELNGKLTGMAFRVP +VSV Sbjct: 181 ATQKTVDGPSGKKWRDGRGANQNVIPATTGAAKAVGKVIPELNGKLTGMAFRVPVPDVSV 240 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLTCRL+KP Y++IKKVVK+ASE LKG L YTE QVVSSDF SDTHSS FDA AGI Sbjct: 241 VDLTCRLKKPTSYEEIKKVVKKASETDLKGFLAYTEDQVVSSDFISDTHSSVFDALAGIQ 300 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 LN FVKL+SWYDNE+GYS+RVVDL+ +MA+K Sbjct: 301 LNPTFVKLVSWYDNEYGYSHRVVDLIEYMATK 332 >4P8R-A nrPDB Length = 339 Score = 543 bits (1399), Expect = e-155, Method: Composition-based stats. Identities = 214/331 (64%), Positives = 257/331 (77%), Gaps = 3/331 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 ++VG+NGFGRIGR+V RAA ++IV IND +D +YM YM +YDSTHG+F G V+ + Sbjct: 11 IRVGINGFGRIGRVVFRAAQRRNDIEIVGIND-LLDADYMAYMLKYDSTHGRFEGAVEVQ 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 G LV+NG I + ERDP+ +KW + + VVESTG+F + + A H+Q GAK+V+I+ Sbjct: 70 GGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITG 129 Query: 124 PSAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PS D PMFVMGVNH Y I+SNASCTTNCLAPLAKV++D FGIVEGLMTTVHA T Sbjct: 130 PSKDDTPMFVMGVNHTTYKGE-AIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATT 188 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGK+IP LNGKLTGMAFRVPT NVSV Sbjct: 189 ATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSV 248 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLT RLE+PA Y I +K ASEG LKGILGY + ++VSSD N +S FDA AGI+ Sbjct: 249 VDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGIS 308 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 LND+FVKL+SWYDNE GYSN+V+DL+AH+ Sbjct: 309 LNDNFVKLVSWYDNETGYSNKVLDLIAHITK 339 >4MVJ-P nrPDB Length = 355 Score = 543 bits (1399), Expect = e-155, Method: Composition-based stats. Identities = 218/331 (65%), Positives = 264/331 (79%), Gaps = 3/331 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR+V RAA ++IVAIND +D +YM YM +YDSTHG+F GTV+ + Sbjct: 27 IKVGINGFGRIGRIVFRAAQKRSDIEIVAIND-LLDADYMAYMLKYDSTHGRFDGTVEVK 85 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +G L++NG I + ERDP+ +KW + G + V E+TG+F T E A H+ GAK+V+++ Sbjct: 86 DGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTG 145 Query: 124 PSAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 PS D PMFV G N +KY I+SNASCTTNCLAPLAKVI+DNFGI+EGLMTTVHA T Sbjct: 146 PSKDNTPMFVKGANFDKYAGQD-IVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATT 204 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP+STGAAKAVGKV+PELNGKLTGMAFRVPT NVSV Sbjct: 205 ATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSV 264 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLT RLEK A Y+ IK VK A+EG +KG+LGYTE VVS+DFN + +S FDA AGIA Sbjct: 265 VDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIA 324 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 LND+FVKL+SWYDNE GYSN+V+DL+AH++ Sbjct: 325 LNDNFVKLVSWYDNETGYSNKVLDLIAHISK 355 >1VSU-A nrPDB Length = 359 Score = 541 bits (1395), Expect = e-154, Method: Composition-based stats. Identities = 218/333 (65%), Positives = 259/333 (77%), Gaps = 4/333 (1%) Query: 6 VGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENG 65 +G+NGFGRIGRLV RA + +VAINDPF+D+ YM Y+ +YDS HG F+GTV+ Sbjct: 25 LGINGFGRIGRLVLRACMERNDITVVAINDPFMDVEYMAYLLKYDSVHGNFNGTVEVSGK 84 Query: 66 KLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPS 125 L ING + +FQ +DP++I WG +GA+ V ESTGVFTT EKA HL+GGAK+VIISAP Sbjct: 85 DLCINGKVVKVFQAKDPAEIPWGASGAQIVCESTGVFTTEEKASLHLKGGAKKVIISAPP 144 Query: 126 AD-APMFVMGVNHEKYDNSL-KIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 D PM+VMGVN+ +YD S +ISNASCTTNCLAPLAK+I+D FGIVEGLMTTVH++TA Sbjct: 145 KDNVPMYVMGVNNTEYDPSKFNVISNASCTTNCLAPLAKIINDKFGIVEGLMTTVHSLTA 204 Query: 184 TQKTVDGPSG--KLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q TVDGPS K WR GR A NIIPASTGAAKAVGKVIP LNGKLTGMA RVPT +VS Sbjct: 205 NQLTVDGPSKGGKDWRAGRCAGNNIIPASTGAAKAVGKVIPALNGKLTGMAIRVPTPDVS 264 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLTC+L KPA ++I + VK+AS GP+KGI+GYT VVS+DF +SS FD A I Sbjct: 265 VVDLTCKLAKPASIEEIYQAVKEASNGPMKGIMGYTSDDVVSTDFIGCKYSSIFDKNACI 324 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 ALND FVKLISWYDNE GYSNR+VDL ++AS+ Sbjct: 325 ALNDSFVKLISWYDNESGYSNRLVDLAVYVASR 357 >2I5P-O nrPDB Length = 342 Score = 536 bits (1381), Expect = e-153, Method: Composition-based stats. Identities = 210/329 (63%), Positives = 256/329 (77%), Gaps = 1/329 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 V + +NGFGRIGRLV R A +D+VAINDPFI ++Y YMF+YDSTHGK+ G V + Sbjct: 15 VSIAINGFGRIGRLVLRIALERKNIDVVAINDPFISVDYAAYMFKYDSTHGKYKGEVSHD 74 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 L+ING + +FQE+DP+ + WG G + V+STGVF ++ A H+ GAK+V+I+A Sbjct: 75 GSNLIINGKKVAVFQEKDPATLPWGKLGVDIAVDSTGVFKELDSAQKHIDAGAKKVVITA 134 Query: 124 PSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITA 183 PS APMFV+GVN +KY+ I+SNASCTTNCLAP+AK+I+D FGI EGLMTTVH+ITA Sbjct: 135 PSKTAPMFVVGVNEDKYNGEK-IVSNASCTTNCLAPIAKIINDEFGIEEGLMTTVHSITA 193 Query: 184 TQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVV 243 TQKTVDGPS K WR GR A NIIP+STGAAKAVGKV+PEL GKLTGMAFRVPT +VSVV Sbjct: 194 TQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTTDVSVV 253 Query: 244 DLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIAL 303 DLT +L K A YD+IK VK+ SEG LK ++GYTE VVSSDF DTHS+ FDA AGI L Sbjct: 254 DLTVKLVKAATYDEIKAAVKKVSEGKLKDVVGYTEDAVVSSDFLGDTHSTIFDAAAGIQL 313 Query: 304 NDHFVKLISWYDNEFGYSNRVVDLMAHMA 332 + FVKL++WYDNE+GYS RVVDL+ H+A Sbjct: 314 SPKFVKLVAWYDNEYGYSTRVVDLVEHVA 342 >4LSM-A nrPDB Length = 346 Score = 533 bits (1374), Expect = e-152, Method: Composition-based stats. Identities = 213/331 (64%), Positives = 259/331 (78%), Gaps = 3/331 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +K+G+NGFGRIGR+V RAA + ++IV IND +D +YM YM +YDSTHG++ G V+ Sbjct: 17 IKIGINGFGRIGRMVFRAAQHRNDIEIVGIND-LLDADYMAYMLKYDSTHGRYGGMVEVR 75 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 G LV+NG I + ERDP+ +KW + GA VVESTG+F T E A H+Q GAK+V+++ Sbjct: 76 EGALVVNGKKIRVTSERDPANLKWNEVGAVVVVESTGLFLTDETARKHIQAGAKKVVMTG 135 Query: 124 PSAD-APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P D PMFVMGVN+ Y I+SNASCTTNCLAPLAK+IH+ FGIVEGLMTTVHA T Sbjct: 136 PPKDDTPMFVMGVNNTMYKGQE-IVSNASCTTNCLAPLAKIIHEKFGIVEGLMTTVHATT 194 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 ATQKTVDGPS K WR GRGA QNIIP++TGAAKAVGKVIP LNG+LTGMAFRVPT NVSV Sbjct: 195 ATQKTVDGPSQKDWRGGRGAAQNIIPSATGAAKAVGKVIPALNGRLTGMAFRVPTPNVSV 254 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDLT RLE+PA Y+ I +K ASEG LKGILGYTE +VVS+D N +S FD AGI+ Sbjct: 255 VDLTARLERPATYEQICAAIKAASEGELKGILGYTEDEVVSTDMNGVALTSVFDVKAGIS 314 Query: 303 LNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 LND FVKLISWYDNE GYS++V+DL+A++++ Sbjct: 315 LNDRFVKLISWYDNETGYSHKVLDLVAYISA 345 >1NPT-O nrPDB Length = 334 Score = 524 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 178/333 (53%), Positives = 228/333 (68%), Gaps = 4/333 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGR V RAA + +++VA+ND D N + ++ +YDS HG+ V Sbjct: 2 VKVGINGFGRIGRNVFRAALKNPDIEVVAVND-LTDANTLAHLLKYDSVHGRLDAEVSVN 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 LV+NG I + ERDP + WG+ G + VVESTG FT E A HL+ GAK+VIISA Sbjct: 61 GNNLVVNGKEIIVKAERDPENLAWGEIGVDIVVESTGRFTKREDAAKHLEAGAKKVIISA 120 Query: 124 PSADAP-MFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + VMGVN +KYD + +ISNAS TTNCLAP AKV+H+ FGIV G+MTTVH+ Sbjct: 121 PAKNEDITIVMGVNQDKYDPKAHHVISNASATTNCLAPFAKVLHEQFGIVRGMMTTVHSY 180 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P K R R A ++IIP +TGAAKAV V+PEL GKL GMA RVPT NVS Sbjct: 181 TNDQRILDLPH-KDLRRARAAAESIIPTTTGAAKAVALVLPELKGKLNGMAMRVPTPNVS 239 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDL LEK +++ +K A+EG LKGIL Y+E +VS D+N T SST DA + + Sbjct: 240 VVDLVAELEKEVTVEEVNAALKAAAEGELKGILAYSEEPLVSRDYNGSTVSSTIDALSTM 299 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 ++ VK++SWYDNE GYS+RVVDL A++ASK Sbjct: 300 VIDGKMVKVVSWYDNETGYSHRVVDLAAYIASK 332 >1HDG-O nrPDB Length = 332 Score = 519 bits (1337), Expect = e-148, Method: Composition-based stats. Identities = 159/330 (48%), Positives = 213/330 (64%), Gaps = 5/330 (1%) Query: 5 KVGVNGFGRIGRLVTRAAFNS--GKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 +V +NGFGRIGRLV R + +++VAIND D + ++ +YDS H KF G V+ Sbjct: 2 RVAINGFGRIGRLVYRIIYERKNPDIEVVAIND-LTDTKTLAHLLKYDSVHKKFPGKVEY 60 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 L+++G I +F E DPSK+ W D G ++V+ESTGVF EKA HLQ GAK+VII+ Sbjct: 61 TENSLIVDGKEIKVFAEPDPSKLPWKDLGVDFVIESTGVFRNREKAELHLQAGAKKVIIT 120 Query: 123 APSADAP-MFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP+ V+G N ++ IIS ASCTTN +AP+ KV+H+ FGIV G++TTVH+ Sbjct: 121 APAKGEDITVVIGCNEDQLKPEHTIISCASCTTNSIAPIVKVLHEKFGIVSGMLTTVHSY 180 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P K R R A NIIP +TGAAKAV V+PE+ GKL GMA RVPT + S Sbjct: 181 TNDQRVLDLPH-KDLRRARAAAVNIIPTTTGAAKAVALVVPEVKGKLDGMAIRVPTPDGS 239 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + DLT +EK +++ V+K+A+EG LKGI+GY + +VSSD T S FDA Sbjct: 240 ITDLTVLVEKETTVEEVNAVMKEATEGRLKGIIGYNDEPIVSSDIIGTTFSGIFDATITN 299 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHM 331 + VK+ SWYDNE+GYSNRVVD + + Sbjct: 300 VIGGKLVKVASWYDNEYGYSNRVVDTLELL 329 >3STH-A nrPDB Length = 361 Score = 518 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 216/336 (64%), Positives = 265/336 (78%), Gaps = 4/336 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 K+G+NGFGRIGRLV RAA G V+++AINDPF+ L+YMVY+ +YDS HG + G V + Sbjct: 24 CKLGINGFGRIGRLVFRAAMERGDVEVLAINDPFMSLDYMVYLLRYDSVHGHYPGEVSHK 83 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +GKL++ G +T+F E++P+ I WG AG Y+ ESTG+F T EKA AHL GAK+VI+SA Sbjct: 84 DGKLIVGGKAVTVFNEKEPTAIPWGQAGVHYICESTGIFLTKEKAQAHLTNGAKKVIMSA 143 Query: 124 PSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P D PMFVMGVN+++Y +S I+SNASCTTNCLAPLAK++HD FGIVEGLMTTVHA+T Sbjct: 144 PPKDDTPMFVMGVNNDQYKSSDVIVSNASCTTNCLAPLAKIVHDKFGIVEGLMTTVHAMT 203 Query: 183 ATQKTVDGPSG--KLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 A Q TVDGPS K WR GR A NIIPASTGAAKAVGK+IP LNGKLTGMAFRVP +V Sbjct: 204 ANQLTVDGPSKGGKDWRAGRSAGVNIIPASTGAAKAVGKIIPSLNGKLTGMAFRVPVPDV 263 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQAS-EGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGA 299 SVVDLTC+L KPAKY+DI VK+A+ GP+KGI+ YT+ +VVSSDF SS FD A Sbjct: 264 SVVDLTCKLAKPAKYEDIVAAVKEAATSGPMKGIISYTDEEVVSSDFVHCKFSSVFDINA 323 Query: 300 GIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 GI LND FVKL+SWYDNE+GYSNR+V+L +M+ ++ Sbjct: 324 GIMLNDTFVKLVSWYDNEWGYSNRLVELAHYMSVQD 359 >2EP7-A nrPDB Length = 342 Score = 510 bits (1314), Expect = e-145, Method: Composition-based stats. Identities = 158/341 (46%), Positives = 229/341 (67%), Gaps = 13/341 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR RA++ +++IVAIND D ++ ++ +YDS HG F G+V+A+ Sbjct: 3 IKVGINGFGRIGRSFFRASWGREEIEIVAIND-LTDAKHLAHLLKYDSVHGIFKGSVEAK 61 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + +V++G I +F ++DPS+I WGD G + V+E+TGVF E A HLQGGAK+VII+A Sbjct: 62 DDSIVVDGKEIKVFAQKDPSQIPWGDLGVDVVIEATGVFRDRENASKHLQGGAKKVIITA 121 Query: 124 PSADAP-MFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + V+GVN EKY+ IISNASCTTNCLAP KV+++ FG+ +G M TVHA Sbjct: 122 PAKNPDITVVLGVNEEKYNPKEHNIISNASCTTNCLAPCVKVLNEAFGVEKGYMVTVHAY 181 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P K +R R A NI+P +TGAAKA+G+VIPEL GKL G A RVP + S Sbjct: 182 TNDQRLLDLPH-KDFRRARAAAINIVPTTTGAAKAIGEVIPELKGKLDGTARRVPVPDGS 240 Query: 242 VVDLTCRLEK-PAKYDDIKKVVKQASEG-------PLKGILGYTEHQVVSSDFNSDTHSS 293 ++DLT + K P+ +++ + ++A++ LK IL Y E +VS+D + HS+ Sbjct: 241 LIDLTVVVNKAPSSVEEVNEKFREAAQKYRESGKVYLKEILQYCEDPIVSTDIVGNPHSA 300 Query: 294 TFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 FDA + D+ V + +WYDNE+GYS R+ DL+ ++A + Sbjct: 301 IFDAPLTQVI-DNLVHIAAWYDNEWGYSCRLRDLVIYLAER 340 >6OK4-A nrPDB Length = 342 Score = 510 bits (1313), Expect = e-145, Method: Composition-based stats. Identities = 189/330 (57%), Positives = 233/330 (70%), Gaps = 3/330 (0%) Query: 4 VKVGVNGFGRIGRLVTRAAFNS-GKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 +++ +NGFGRIGRLV R +++VAIND + + + Y+F+YDSTHG F Sbjct: 9 MRIVINGFGRIGRLVLRQILKRNSPIEVVAIND-LVAGDLLTYLFKYDSTHGSFAPQATF 67 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 +G LV+ I E+D K+ W D + VVESTG+F + A HL GAKRV+I+ Sbjct: 68 SDGCLVMGERKIRFLAEKDVQKLPWKDLDVDVVVESTGLFVNRDDAAKHLDSGAKRVLIT 127 Query: 123 APS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP+ D P FVMGVNH+++D + IISNASCTTNCLAPLAKV+ DNFGI EGLMTTVHA Sbjct: 128 APAKGDVPTFVMGVNHQQFDPADVIISNASCTTNCLAPLAKVLLDNFGIEEGLMTTVHAA 187 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 TATQ VDGPS K WR GRGA QNIIPASTGAAKAVG +PEL GKLTGMAFRVP A+VS Sbjct: 188 TATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS 247 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 VVDLT +L Y+ I + VK A+ +K I+ YTE VVSSDF +SS FDA AG+ Sbjct: 248 VVDLTVKLSSATTYEAICEAVKHAANTSMKNIMYYTEEAVVSSDFIGCEYSSIFDAQAGV 307 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHM 331 ALND F KL++WYDNE GY+ R+VDL+ ++ Sbjct: 308 ALNDRFFKLVAWYDNEIGYATRIVDLLEYV 337 >1ML3-A nrPDB Length = 359 Score = 504 bits (1299), Expect = e-143, Method: Composition-based stats. Identities = 180/352 (51%), Positives = 238/352 (67%), Gaps = 20/352 (5%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 +KVG+NGFGRIGR+V +A G ++D+VA+ D D Y Y +YD+ HGKF Sbjct: 3 IKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMNTDAEYFAYQMRYDTVHGKFKYE 62 Query: 60 VK--------AENGKLVINGNPITIF-QERDPSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 V A++ LV+NG+ I +R+P+ + WG G EYV+ESTG+FT A Sbjct: 63 VTTTKSSPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAAEG 122 Query: 111 HLQGGAKRVIISAP-SADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVI-HDN 167 HL+GGA++V+ISAP S A VMGVNH +Y+ ++SNASCTTNCLAP+ V+ + Sbjct: 123 HLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHVVSNASCTTNCLAPIVHVLVKEG 182 Query: 168 FGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGK 227 FG+ GLMTT+H+ TATQKTVDG S K WR GR A NIIP++TGAAKAVG VIP GK Sbjct: 183 FGVQTGLMTTIHSYTATQKTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQGK 242 Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFN 287 LTGM+FRVPT +VSVVDLT + +I +K+AS+ +KGILGYT+ ++VS+DF Sbjct: 243 LTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRASKTYMKGILGYTDEELVSADFI 302 Query: 288 SDTHSSTFDAGAGIALN----DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 +D SS +D+ A + N F K++SWYDNE+GYS+RVVDL+ HMASK+ Sbjct: 303 NDNRSSIYDSKATLQNNLPKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKD 354 >3L0D-A nrPDB Length = 356 Score = 504 bits (1298), Expect = e-143, Method: Composition-based stats. Identities = 149/334 (44%), Positives = 210/334 (62%), Gaps = 5/334 (1%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSG--KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 V+V +NGFGRIGR + RA SG +++VA+ND + ++ +YDS HG F GTV Sbjct: 23 SVRVAINGFGRIGRNILRAIIESGRQDIEVVALND-LGSVETNAHLLRYDSVHGCFPGTV 81 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 + + I + I +F ERDP+++ W + +E TG+FT +KA AHL GAKRV+ Sbjct: 82 QVVGDAIDIGSSLIKVFAERDPAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVL 141 Query: 121 ISAPSADAP-MFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVH 179 +SAPS A V GVNH+ +ISNASCTTNCLAP+A+V+H+ GI +G MTT+H Sbjct: 142 VSAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAPVAQVLHNTVGIEKGFMTTIH 201 Query: 180 AITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTAN 239 + T Q +D L+R R A ++IP STGAAKAVG V+PEL G L G++ RVPT N Sbjct: 202 SYTGDQPVLDTMHRDLYR-ARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPN 260 Query: 240 VSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGA 299 VSVVDLT ++ ++I ++ A++G LKGIL YT+ ++VS DFN + HS+ F Sbjct: 261 VSVVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQ 320 Query: 300 GIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 ++ +++ WYDNE+G+SNR+ D A Sbjct: 321 TKVIDGQLCRVLVWYDNEWGFSNRMCDTAVAFAK 354 >4BOY-A nrPDB Length = 354 Score = 502 bits (1293), Expect = e-142, Method: Composition-based stats. Identities = 157/335 (46%), Positives = 215/335 (64%), Gaps = 7/335 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNS---GKVDIVAINDPFIDLNYMVYMFQYDSTHGKF-HGT 59 V+V +NGFGRIGR R K++IV IND D ++ +YDS G F Sbjct: 19 VRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDT-SDPRTNAHLLKYDSMLGIFQDAE 77 Query: 60 VKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRV 119 + A++ + G+ + +R+P + W G + V+E+TGVFT+ E A HL GAK+V Sbjct: 78 ITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKV 137 Query: 120 IISAPS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 +I+AP + P +V+GVNH YD S I+SNASCTTNCLAP+ KV+H+ FGI +G+MTT Sbjct: 138 LITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTT 197 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D L R A NI+P STGAAKAVG VIPEL GKL G+A RVPT Sbjct: 198 HSYTGDQRLLDASHRDLR-RARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTP 256 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVD ++EKP + + +V+K+ASE +KGI+ Y+E ++VSSD+ SS DA Sbjct: 257 NVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDAS 316 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + L + VK+++WYDNE+GYS RV+DL HMA+ Sbjct: 317 LTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAA 351 >3GNQ-A nrPDB Length = 344 Score = 500 bits (1288), Expect = e-142, Method: Composition-based stats. Identities = 163/337 (48%), Positives = 216/337 (64%), Gaps = 8/337 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG---KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 ++V +NG+GRIGR RA + +G ++IVAIND D ++ QYD+ HGKF G V Sbjct: 11 IRVAINGYGRIGRNTLRAFYENGKKHDLEIVAIND-LGDAKTNAHLTQYDTAHGKFPGEV 69 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 + LV+NG+ I + R+P+++ WG+ G + V+E TG FT+ EKA AHL+GGAK+VI Sbjct: 70 SVDGDYLVVNGDRIRVLANRNPAELPWGELGVDVVMECTGFFTSKEKASAHLKGGAKKVI 129 Query: 121 ISAPSA-DAP-MFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 ISAP D V GVNH+ +ISNASCTTNCLAPL K ++D G+ GLMTT+ Sbjct: 130 ISAPGGKDVDATIVYGVNHDVLKAEHTVISNASCTTNCLAPLVKPLNDKIGLETGLMTTI 189 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 HA T Q D L R R A + IP TGAA AVG V+PELNGKL G A RVPT Sbjct: 190 HAYTNDQVLTDVYHEDL-RRARSATHSQIPTKTGAAAAVGLVLPELNGKLDGYAIRVPTI 248 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVS+VDL+ ++ ++ ++K+ASEG LKGILGY E +VS DFN + SSTFDA Sbjct: 249 NVSIVDLSFIAKRDTTAAEVNAIMKEASEGALKGILGYNEAPLVSIDFNHNPASSTFDAT 308 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 + VK+ SWYDNE+G+SNR++D +A+ + Sbjct: 309 LTKV-SGRLVKVSSWYDNEWGFSNRMLDTAIALANAK 344 >5VMT-A nrPDB Length = 342 Score = 500 bits (1287), Expect = e-142, Method: Composition-based stats. Identities = 150/337 (44%), Positives = 205/337 (60%), Gaps = 10/337 (2%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKA 62 +KV +NGFGRIGRL R + +++ A+ND ++++F+YDST G+F GT + Sbjct: 10 SIKVAINGFGRIGRLALRQIEKAHGIEVAAVND-LTPAEMLLHLFKYDSTQGRFQGTAEL 68 Query: 63 ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIIS 122 ++ +V+NG I +F +P ++ WG+ G + V+E TG FT KA AH++ GA++V+IS Sbjct: 69 KDDAIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVIS 128 Query: 123 APSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP D V GVN + D S +IS ASCTTNCLAP+A V+ FG+VEGLMTT+HA Sbjct: 129 APGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAAVLQKEFGVVEGLMTTIHAY 188 Query: 182 TATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q T+D P K R R A NI+P STGAAKA+G VIPELNGKL G A RVP A Sbjct: 189 TGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATG 248 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 S+ +L LE+PA ++I +K AS GY E Q+VSSD + S FDA Sbjct: 249 SLTELVSVLERPATKEEINAAMKAASSES----YGYNEDQIVSSDVVGIEYGSLFDATQT 304 Query: 301 IAL---NDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + VK ++WYDNE Y+ ++V + + A K Sbjct: 305 RVMTVGGKQLVKTVAWYDNEMSYTCQLVRTLEYFAGK 341 >3DOC-A nrPDB Length = 335 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 149/331 (45%), Positives = 215/331 (64%), Gaps = 5/331 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG--KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 V+V +NGFGRIGR + RA SG + +VAIND + ++ +YDS HG+F V+ Sbjct: 3 VRVAINGFGRIGRNILRAIVESGRTDIQVVAIND-LGPVETNAHLLRYDSVHGRFPKEVE 61 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + + PI + R+P+++ W + + +E TG+FT+ +KA HL+ GAKRVI+ Sbjct: 62 VAGDTIDVGYGPIKVHAVRNPAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVIV 121 Query: 122 SAPSADAP-MFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 SAP+ A V GVN++K +ISNASCTTNCLAP+A+V++D GI +G MTT+H+ Sbjct: 122 SAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAPVAQVLNDTIGIEKGFMTTIHS 181 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q T+D L+R R A ++IP STGAAKAVG V+PEL GKL G+A RVPT NV Sbjct: 182 YTGDQPTLDTMHKDLYR-ARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVAIRVPTPNV 240 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDLT ++ +++ +++A+ G LKGILGYT+ ++VS DFN D+HSS F Sbjct: 241 SVVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQT 300 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHM 331 ++ V+++SWYDNE+G+S+R+ D + Sbjct: 301 KVMDGTMVRILSWYDNEWGFSSRMSDTAVAL 331 >2X0N-A nrPDB Length = 359 Score = 497 bits (1280), Expect = e-141, Method: Composition-based stats. Identities = 185/352 (52%), Positives = 241/352 (68%), Gaps = 20/352 (5%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 +KVG+NGFGRIGR+V +A + G ++D+VA+ D D Y Y +YDS HGKF + Sbjct: 3 IKVGINGFGRIGRMVFQALCDDGLLGNEIDVVAVVDMNTDARYFAYQMKYDSVHGKFKHS 62 Query: 60 VK--------AENGKLVINGNPITIF-QERDPSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 V A++ LV+NG+ I +R+P+ + WG G EYV+ESTG+FT A Sbjct: 63 VSTTKSKPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTVKSAAEG 122 Query: 111 HLQGGAKRVIISAP-SADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVI-HDN 167 HL+GGA++V+ISAP S A FVMGVNH Y+ ++SNASCTTNCLAPL V+ + Sbjct: 123 HLRGGARKVVISAPASGGAKTFVMGVNHNNYNPREQHVVSNASCTTNCLAPLVHVLVKEG 182 Query: 168 FGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGK 227 FGI GLMTTVH+ TATQKTVDG S K WR GR A NIIP++TGAAKAVG VIP GK Sbjct: 183 FGISTGLMTTVHSYTATQKTVDGVSVKDWRGGRAAALNIIPSTTGAAKAVGMVIPSTQGK 242 Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFN 287 LTGMAFRVPTA+VSVVDLT + +I +K+AS+ +K ILGYT+ ++VS+DF Sbjct: 243 LTGMAFRVPTADVSVVDLTFIATRDTSIKEIDAALKRASKTYMKNILGYTDEELVSADFI 302 Query: 288 SDTHSSTFDAGAGIALN----DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 SD+ SS +D+ A + N F K++SWYDNE+GYS+RVVDL+ HMA+++ Sbjct: 303 SDSRSSIYDSKATLQNNLPNERRFFKIVSWYDNEWGYSHRVVDLVRHMAARD 354 >5M6D-A nrPDB Length = 355 Score = 497 bits (1279), Expect = e-141, Method: Composition-based stats. Identities = 157/337 (46%), Positives = 201/337 (59%), Gaps = 10/337 (2%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 G VKVG+NGFGRIGRL R N V++ IND D + ++ +YD+T G+F GTV+ Sbjct: 21 GVVKVGINGFGRIGRLAFRRIQNVEGVEVTRIND-LTDPVMLAHLLKYDTTQGRFDGTVE 79 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + G +NG I + ERDP +I W G E V+E+TG F E A HL+GGAK+V+I Sbjct: 80 VKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAKKEAAEKHLKGGAKKVVI 139 Query: 122 SAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 +AP D V NH+ D + +IS ASCTTNCLAP+AK + DNFG+VEGLMTT+HA Sbjct: 140 TAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMAKALQDNFGVVEGLMTTIHA 199 Query: 181 ITATQKTVDGPSG-KLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTAN 239 T Q +DGP R R NI+P STGAAKA+G VIPELNGKL G A RVPT Sbjct: 200 YTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPTPT 259 Query: 240 VSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGA 299 SV +L LEK D++ +K AS GYTE +VSSD ++ S FDA Sbjct: 260 GSVTELVAVLEKNVTVDEVNAAMKAASNES----YGYTEDPIVSSDIVGMSYGSLFDATQ 315 Query: 300 GIAL---NDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 L VK++SWYDNE Y+ ++V + + A Sbjct: 316 TKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAK 352 >1I33-A nrPDB Length = 360 Score = 494 bits (1273), Expect = e-140, Method: Composition-based stats. Identities = 176/352 (50%), Positives = 240/352 (68%), Gaps = 20/352 (5%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 +KVG+NGFGRIGR+V +A + G ++D+VA+ D + Y Y ++D+ HG+ T Sbjct: 3 IKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMSTNAEYFAYQMKHDTVHGRPKYT 62 Query: 60 VKA--------ENGKLVINGNPITIF-QERDPSKIKWGDAGAEYVVESTGVFTTMEKAGA 110 V+A LV+NG+ I +R+P+ + WG G +YV+ESTG+FT KA Sbjct: 63 VEAVKSSPSVETADVLVVNGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKAEG 122 Query: 111 HLQGGAKRVIISAP-SADAPMFVMGVNHEKYDN-SLKIISNASCTTNCLAPLAKVI-HDN 167 H++GGAK+V+ISAP S A VMGVN +Y S ++SNASCTTNCLAP+ V+ +N Sbjct: 123 HIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHVVSNASCTTNCLAPIVHVLTKEN 182 Query: 168 FGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGK 227 FGI GLMTT+H+ TATQKTVDG S K WR GR A NIIP++TGAAKAVG VIP GK Sbjct: 183 FGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTKGK 242 Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFN 287 LTGM+FRVPT +VSVVDLT R + +I K +K+A++ +KGILG+T+ ++VS+DF Sbjct: 243 LTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKAAQTYMKGILGFTDEELVSADFI 302 Query: 288 SDTHSSTFDAGAGIALN----DHFVKLISWYDNEFGYSNRVVDLMAHMASKE 335 +D SS +D+ A + N F K++SWYDNE+ YS+RVVDL+ +MA+K+ Sbjct: 303 NDNRSSVYDSKATLQNNLPGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKD 354 >3HJA-A nrPDB Length = 356 Score = 487 bits (1255), Expect = e-138, Method: Composition-based stats. Identities = 169/340 (49%), Positives = 226/340 (66%), Gaps = 11/340 (3%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 G +K+ +NGFGRIGR V + AF G +DIVAIND D + ++ +YDST G ++ V+ Sbjct: 20 GSMKLAINGFGRIGRNVFKIAFERG-IDIVAIND-LTDPKTLAHLLKYDSTFGVYNKKVE 77 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTM--EKAG--AHL-QGGA 116 + +G +V++G I I ERDP + W G + V+ESTGVF++ +K G H+ GA Sbjct: 78 SRDGAIVVDGREIKIIAERDPKNLPWAKLGIDVVIESTGVFSSATSDKGGYLDHVNHAGA 137 Query: 117 KRVIISAPSADA-PMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLM 175 K+VI++ P+ D V+GVN ++ LK +SNASCTTNCLAPLAKV+H++FGI +GLM Sbjct: 138 KKVILTVPAKDEIKTIVLGVNDHDINSDLKAVSNASCTTNCLAPLAKVLHESFGIEQGLM 197 Query: 176 TTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRV 235 TTVHA T Q+ +D P L R R A +IIP STGAAKAVG V+PEL GKL G + RV Sbjct: 198 TTVHAYTNDQRILDLPHSDL-RRARAAALSIIPTSTGAAKAVGLVLPELKGKLNGTSMRV 256 Query: 236 PTANVSVVDLTCRL-EKPAKYDDIKKVVKQASEGP-LKGILGYTEHQVVSSDFNSDTHSS 293 P S+VDLT +L +K ++I V+++ASE P LKGILGYTE +VSSD ++HSS Sbjct: 257 PVPTGSIVDLTVQLKKKDVTKEEINSVLRKASETPELKGILGYTEDPIVSSDIKGNSHSS 316 Query: 294 TFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 D + L + F K++SWYDNEFGYS RVVDL + Sbjct: 317 IVDGLETMVLENGFAKILSWYDNEFGYSTRVVDLAQKLVK 356 >6FZI-A nrPDB Length = 332 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 151/336 (44%), Positives = 208/336 (61%), Gaps = 10/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKV +NGFGRIGRL R ++ + ++VAIND D + ++F+YDS G+F+G ++ + Sbjct: 2 VKVAINGFGRIGRLALRLMIDNPEFEVVAIND-LTDAKTLAHLFKYDSAQGRFNGEIEVK 60 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 G V+NG I + + +P+++ WG+ G + V+E TG F + EKA AHL GAK+V+ISA Sbjct: 61 EGAFVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISA 120 Query: 124 PSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P+ D P V VNH+ D S +IS ASCTTNCLAP+AK ++DNFG+ +G MTT+HA T Sbjct: 121 PAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAKALNDNFGLNKGFMTTIHAYT 180 Query: 183 ATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q T+D P K R R A NI+P STGAAKA+G VIPEL GKL G A RVP S Sbjct: 181 NDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS 240 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + +L C L+K +++ +K AS GYTE +VSSD + S FDA Sbjct: 241 LTELVCTLDKKVTVEEVNAAMKAASNES----FGYTEDPIVSSDVIGISFGSLFDATQTK 296 Query: 302 AL---NDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + VK+ SWYDNE Y+N+++ + + SK Sbjct: 297 IMEVDGQQLVKVASWYDNEASYTNQLIRTLKCLVSK 332 >6FZH-A nrPDB Length = 336 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 154/336 (45%), Positives = 197/336 (58%), Gaps = 11/336 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRL R N V++ IND D N + ++ +YD+T G+F GTV+ + Sbjct: 3 VKVGINGFGRIGRLAFRRIQNIEGVEVTRIND-LTDPNMLAHLLKYDTTQGRFDGTVEVK 61 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQG-GAKRVIIS 122 G +NGN I + ERDP I W G E V+E+TG F E A HL GAK+V+I+ Sbjct: 62 EGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAKKEAAEKHLHANGAKKVVIT 121 Query: 123 APSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP D V NH+ D + +IS ASCTTNCLAP+AK +HD FGI +GLMTT+HA Sbjct: 122 APGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALHDAFGIQKGLMTTIHAY 181 Query: 182 TATQKTVDGPSG-KLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q +DGP R R NI+P STGAAKA+G VIPELNGKL G A RVP Sbjct: 182 TGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTG 241 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SV +L L+K D+I +K AS GYTE +VSSD ++ S FDA Sbjct: 242 SVTELVVTLDKNVSVDEINAAMKAASNDS----FGYTEDPIVSSDIVGVSYGSLFDATQT 297 Query: 301 IAL---NDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + VK++SWYDNE Y+ ++V + + A Sbjct: 298 KVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAK 333 >5JY6-A nrPDB Length = 356 Score = 483 bits (1245), Expect = e-137, Method: Composition-based stats. Identities = 148/336 (44%), Positives = 201/336 (59%), Gaps = 11/336 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKVG+NGFGRIGRL R N V++ IND D N + ++ +YD+T G+F GTV+ + Sbjct: 23 VKVGINGFGRIGRLAFRRIQNVEGVEVTRIND-LTDPNMLAHLLKYDTTQGRFDGTVEVK 81 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHL-QGGAKRVIIS 122 G +NG + + ER+P+ I W G E V+E+TG F + EKA H+ + GAK+V+I+ Sbjct: 82 EGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVIT 141 Query: 123 APSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 AP D V NH+ D + +IS ASCTTNCLAP+AK + DNFG+ +GLMTT+HA Sbjct: 142 APGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAY 201 Query: 182 TATQKTVDGPSG-KLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q +DGP R R NI+P STGAAKA+G VIPELNGKL G A RVP Sbjct: 202 TGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTG 261 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SV +L LEK +++ +K A+ GYTE +VSSD ++ S FDA Sbjct: 262 SVTELVATLEKDVTVEEVNAAMKAAANDS----YGYTEDPIVSSDIVGISYGSLFDATQT 317 Query: 301 I---ALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + VK++SWYDNE Y++++V + + A Sbjct: 318 KVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAK 353 >3VAZ-P nrPDB Length = 344 Score = 482 bits (1241), Expect = e-137, Method: Composition-based stats. Identities = 150/336 (44%), Positives = 209/336 (62%), Gaps = 11/336 (3%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 VKV +NGFGRIGRL R +++VA+ND D + + ++ +YD+ G+F G V+ Sbjct: 11 VKVAINGFGRIGRLAFRRIQEVEGLEVVAVND-LTDDDMLAHLLKYDTMQGRFTGEVEVV 69 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 +G +NG + F E D SK+ W D + V+E TG +T +KA AH++ GAK+V+ISA Sbjct: 70 DGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISA 129 Query: 124 PS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 P+ D V NH++ D S ++S ASCTTN LAP+AKV++D+FG+VEGLMTT+HA T Sbjct: 130 PATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYT 189 Query: 183 ATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 Q T D P K R R A +NIIP STGAAKA+GKVIPE++GKL G A RVP A S Sbjct: 190 GDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGS 249 Query: 242 VVDLTCRLEK-PAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 + +LT LEK + + + +K AS GYTE ++VSSD T+ S FDA Sbjct: 250 LTELTVVLEKQDVTVEQVNEAMKNASNES----FGYTEDEIVSSDVVGMTYGSLFDATQT 305 Query: 301 IAL---NDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + + VK+ +WYDNE Y+ ++V +A++A Sbjct: 306 RVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAE 341 >1VC2-A nrPDB Length = 331 Score = 478 bits (1232), Expect = e-135, Method: Composition-based stats. Identities = 158/333 (47%), Positives = 211/333 (63%), Gaps = 6/333 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR V R G V++ IND D + ++ +YDST+G+F G V + Sbjct: 1 MKVGINGFGRIGRQVFRILHERG-VEVALIND-LTDNKTLAHLLKYDSTYGRFPGAVGYD 58 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 L ++G I +DP +I W AG VVESTGVFT EKA AHL+ GAK+VII+A Sbjct: 59 EENLYVDGKAIRATAIKDPREIPWKQAGVGVVVESTGVFTDGEKARAHLEAGAKKVIITA 118 Query: 124 PSADAP-MFVMGVNHEKYDNS-LKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ + V+GVNHE+YD + I+SNASCTTN LAP+ KV+ FG+ + LMTTVH+ Sbjct: 119 PAKNEDITVVLGVNHEQYDPAKHHILSNASCTTNSLAPVMKVLEKAFGVEKALMTTVHSY 178 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P K R R A NIIP +TGAAKA V+P L G+ GMA RVPT S Sbjct: 179 TNDQRLLDLPH-KDLRRARAAALNIIPTTTGAAKATALVLPSLKGRFDGMALRVPTPTGS 237 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + D+T L++ +++ +K A+EGPLKGIL YTE ++V D D HSS D Sbjct: 238 ISDITALLKREVTAEEVNAALKAAAEGPLKGILAYTEDEIVLRDIVMDPHSSIVDGKLTK 297 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 A+ + VK+ +WYDNE+GY+NRV DL+ + K Sbjct: 298 AIG-NLVKVFAWYDNEWGYANRVADLVELVLKK 329 >1OBF-O nrPDB Length = 335 Score = 478 bits (1230), Expect = e-135, Method: Composition-based stats. Identities = 159/335 (47%), Positives = 213/335 (63%), Gaps = 8/335 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG---KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 ++V +NG+GRIGR + RA + G ++IVAIND D ++ +YD+ HGKF GTV Sbjct: 2 IRVAINGYGRIGRNILRAHYEGGKSHDIEIVAIND-LGDPKTNAHLTRYDTAHGKFPGTV 60 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 +V+NG+ I + R+P+++ WG + V+E TG FTT EKAGAH++GGAK+VI Sbjct: 61 SVNGSYMVVNGDKIRVDANRNPAQLPWGALKVDVVLECTGFFTTKEKAGAHIKGGAKKVI 120 Query: 121 ISAPSA-DAP-MFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 ISAP D V GVNH ++ +ISNASCTTNCLAPL K ++D G+ +GLMTTV Sbjct: 121 ISAPGGADVDATVVYGVNHGTLKSTDTVISNASCTTNCLAPLVKPLNDKLGLQDGLMTTV 180 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 HA T Q D L R R A ++IP TGAA AVG V+PEL+GKL G A RVPT Sbjct: 181 HAYTNNQVLTDVYHEDL-RRARSATMSMIPTKTGAAAAVGDVLPELDGKLNGYAIRVPTI 239 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVS+VDL+ ++ +++ ++K ASEG LKGIL Y +VS D+N D SST DA Sbjct: 240 NVSIVDLSFVAKRNTTVEEVNGILKAASEGELKGILDYNTEPLVSVDYNHDPASSTVDAS 299 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + VK+ SWYDNE+G+SNR++D + S Sbjct: 300 LTKV-SGRLVKVSSWYDNEWGFSNRMLDTTVALMS 333 >1CER-O nrPDB Length = 331 Score = 476 bits (1225), Expect = e-135, Method: Composition-based stats. Identities = 161/333 (48%), Positives = 214/333 (64%), Gaps = 6/333 (1%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAE 63 +KVG+NGFGRIGR V R + G V++ IND D + ++ +YDS + +F G V + Sbjct: 1 MKVGINGFGRIGRQVFRILHSRG-VEVALIND-LTDNKTLAHLLKYDSIYHRFPGEVAYD 58 Query: 64 NGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISA 123 + L ++G I +DP +I W +AG V+ESTGVFT +KA AHL+GGAK+VII+A Sbjct: 59 DQYLYVDGKAIRATAVKDPKEIPWAEAGVGVVIESTGVFTDADKAKAHLEGGAKKVIITA 118 Query: 124 PSADAP-MFVMGVNHEKYDNS-LKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAI 181 P+ VMGVNHE YD S IISNASCTTN LAP+ KV+ + FG+ + LMTTVH+ Sbjct: 119 PAKGEDITIVMGVNHEAYDPSRHHIISNASCTTNSLAPVMKVLEEAFGVEKALMTTVHSY 178 Query: 182 TATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVS 241 T Q+ +D P K R R A NIIP +TGAAKA V+P L G+ GMA RVPTA S Sbjct: 179 TNDQRLLDLPH-KDLRRARAAAINIIPTTTGAAKATALVLPSLKGRFDGMALRVPTATGS 237 Query: 242 VVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGI 301 + D+T L++ +++ +K A+EGPLKGIL YTE ++V D D HSS DA Sbjct: 238 ISDITALLKREVTAEEVNAALKAAAEGPLKGILAYTEDEIVLQDIVMDPHSSIVDAKLTK 297 Query: 302 ALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 AL + VK+ +WYDNE+GY+NRV DL+ + K Sbjct: 298 ALG-NMVKVFAWYDNEWGYANRVADLVELVLRK 329 >1JN0-O nrPDB Length = 335 Score = 473 bits (1217), Expect = e-134, Method: Composition-based stats. Identities = 152/334 (45%), Positives = 205/334 (61%), Gaps = 4/334 (1%) Query: 3 KVKVGVNGFGRIGRLVTRAAF-NSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 K+KV +NGFGRIGR R +D+V IND + ++ +YDS G F VK Sbjct: 1 KLKVAINGFGRIGRNFLRCWHGKDSPLDVVVINDT-GGVKQASHLLKYDSILGTFDADVK 59 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + G I + +R+P + WGD G + V+E TGVF + AG HLQ GAK+V+I Sbjct: 60 TAGDSAISVGKVIKVVSDRNPVNLPWGDMGIDLVIEGTGVFVDRDGAGKHLQAGAKKVLI 119 Query: 122 SAPS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 +AP D P +V+GVN E Y ++ IISNASCTTNCLAP KV+ FGI++G MTT H+ Sbjct: 120 TAPGKGDIPTYVVGVNEEGYTHADTIISNASCTTNCLAPFVKVLDQKFGIIKGTMTTTHS 179 Query: 181 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 240 T Q+ +D L R R A NI+P STGAAKAV V+P+L GKL G+A RVPT NV Sbjct: 180 YTGDQRLLDASHRDL-RRARAACLNIVPTSTGAAKAVALVLPQLKGKLNGIALRVPTPNV 238 Query: 241 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 300 SVVDL ++ K +++ +++++ LKGIL + +VS DF SST D+ Sbjct: 239 SVVDLVVQVSKKTFAEEVNAAFRESADQELKGILSVCDEPLVSIDFRCTDVSSTIDSSLT 298 Query: 301 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + + D VK+I+WYDNE+GYS RVVDL +A+K Sbjct: 299 MVMGDDMVKVIAWYDNEWGYSQRVVDLADIVANK 332 >4DIB-A nrPDB Length = 345 Score = 466 bits (1199), Expect = e-132, Method: Composition-based stats. Identities = 152/321 (47%), Positives = 210/321 (65%), Gaps = 4/321 (1%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 +V +NGFGRIGR+V R A +IVAIN + + ++ +YD+ HGKF GTV+A Sbjct: 6 RVAINGFGRIGRMVFRQAIKESAFEIVAINASYPS-ETLAHLIKYDTVHGKFDGTVEAFE 64 Query: 65 GKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAP 124 L+++G I + RDP ++ W D G E V+E+TG F + EKA H++ GAK+VI++AP Sbjct: 65 DHLLVDGKMIRLLNNRDPKELPWTDLGVEVVIEATGKFNSKEKAILHVEAGAKKVILTAP 124 Query: 125 SADAP-MFVMGVNHEKYD-NSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAIT 182 + V+GVN ++ D +ISNASCTTNCLAP+ KV+ + FGI GLMTTVHA T Sbjct: 125 GKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVVKVLDEQFGIENGLMTTVHAYT 184 Query: 183 ATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSV 242 QK +D P K R R Q+IIP +TGAAKA+ KV+P LNGKL GMA RVPT NVS+ Sbjct: 185 NDQKNIDNPH-KDLRRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSL 243 Query: 243 VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIA 302 VDL +++ + I K + G LKGI+ ++E +VS DFN++THS+ D + + Sbjct: 244 VDLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMV 303 Query: 303 LNDHFVKLISWYDNEFGYSNR 323 + D VK+++WYDNE+GYS R Sbjct: 304 MGDRKVKVLAWYDNEWGYSRR 324 >2DUU-A nrPDB Length = 380 Score = 466 bits (1199), Expect = e-132, Method: Composition-based stats. Identities = 151/336 (44%), Positives = 214/336 (63%), Gaps = 7/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG--KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 ++V +NGFGRIGR R F +++VAIN+ D ++ +YDS G+F+ + Sbjct: 3 IRVAINGFGRIGRNFLRCWFGRQNTDLEVVAINNT-SDARTAAHLLEYDSVLGRFNADIS 61 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + + +NG + I +R+P + W + + V+ESTGVF T E A H+Q GAK+V+I Sbjct: 62 YDENSITVNGKTMKIVCDRNPLNLPWKEWDIDLVIESTGVFVTAEGASKHIQAGAKKVLI 121 Query: 122 SAPSA--DAPMFVMGVNHEKYDNSL-KIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 +AP +V+GVN +Y + +ISNASCTTNCLAP+AKV+HDNFGI++G MTT Sbjct: 122 TAPGKAEGVGTYVIGVNDSEYRHEDFAVISNASCTTNCLAPVAKVLHDNFGIIKGTMTTT 181 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D L R A NI+P +TGAAKAV VIPEL GKL G+A RVPT Sbjct: 182 HSYTLDQRILDASHRDLR-RARAAAVNIVPTTTGAAKAVALVIPELKGKLNGIALRVPTP 240 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVDL ++EKP + + +V+++AS+ +KGI+ Y++ +VSSDF SS D+ Sbjct: 241 NVSVVDLVVQVEKPTITEQVNEVLQKASQTTMKGIIKYSDLPLVSSDFRGTDESSIVDSS 300 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + ++ VK+I+WYDNE+GYS RVVDL A K Sbjct: 301 LTLVMDGDLVKVIAWYDNEWGYSQRVVDLAELAARK 336 >3B1K-A nrPDB Length = 339 Score = 462 bits (1190), Expect = e-131, Method: Composition-based stats. Identities = 151/336 (44%), Positives = 214/336 (63%), Gaps = 7/336 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG--KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 ++V +NGFGRIGR R F +++VAIN+ D ++ +YDS G+F+ + Sbjct: 3 IRVAINGFGRIGRNFLRCWFGRQNTDLEVVAINNT-SDARTAAHLLEYDSVLGRFNADIS 61 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 + + +NG + I +R+P + W + + V+ESTGVF T E A H+Q GAK+V+I Sbjct: 62 YDENSITVNGKTMKIVCDRNPLNLPWKEWDIDLVIESTGVFVTAEGASKHIQAGAKKVLI 121 Query: 122 SAPSAD--APMFVMGVNHEKYDNSL-KIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 +AP +V+GVN +Y + +ISNASCTTNCLAP+AKV+HDNFGI++G MTT Sbjct: 122 TAPGKGEGVGTYVIGVNDSEYRHEDFAVISNASCTTNCLAPVAKVLHDNFGIIKGTMTTT 181 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ T Q+ +D L R A NI+P +TGAAKAV VIPEL GKL G+A RVPT Sbjct: 182 HSYTLDQRILDASHRDLR-RARAAAVNIVPTTTGAAKAVALVIPELKGKLNGIALRVPTP 240 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NVSVVDL ++EKP + + +V+++AS+ +KGI+ Y++ +VSSDF SS D+ Sbjct: 241 NVSVVDLVVQVEKPTITEQVNEVLQKASQTTMKGIIKYSDLPLVSSDFRGTDESSIVDSS 300 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 + ++ VK+I+WYDNE+GYS RVVDL A K Sbjct: 301 LTLVMDGDLVKVIAWYDNEWGYSQRVVDLAELAARK 336 >5LD5-A nrPDB Length = 358 Score = 460 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 144/338 (42%), Positives = 194/338 (57%), Gaps = 14/338 (4%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKF--HGTVK 61 VKV +NGFGRIGRL R F +IVAIND D + + +YDS+ G + + +V Sbjct: 20 VKVAINGFGRIGRLAFRQMFGHEGSEIVAIND-LTDPKMLANLLKYDSSQGNYARNHSVV 78 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 A + ++G I I++E D + WG+ + V+E TG +T+ KA AH+ GAK+V+I Sbjct: 79 AGEDSITVDGKTIKIYKEADAHNLPWGELNVDVVLECTGFYTSKAKAQAHIDAGAKKVVI 138 Query: 122 SAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 180 SAP+ D P V VNHE IIS ASCTTNCLAP+AK ++D I G+M+T+HA Sbjct: 139 SAPAGKDLPTIVYNVNHEILTKDDNIISAASCTTNCLAPMAKALNDFAPIQSGIMSTIHA 198 Query: 181 ITATQKTVDGPSGK-LWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTAN 239 T Q +DGP K R R A NI+P STGAAKA+G VIPELNGKL G A RVP Sbjct: 199 FTGDQMVLDGPHRKGDLRRARAAAINIVPNSTGAAKAIGLVIPELNGKLIGSAQRVPVPT 258 Query: 240 VSVVDL--TCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDA 297 S L + +K D I +K AS+ GY E +VSSD T+ S FDA Sbjct: 259 GSTTLLFAVVKSDKEITVDSINAAMKAASD---PETFGYNEDPIVSSDIIGMTYGSLFDA 315 Query: 298 GAGIA--LNDHF--VKLISWYDNEFGYSNRVVDLMAHM 331 + L + V+++SWYDNE Y++++V + + Sbjct: 316 TQTMVQDLGNGLYQVEVVSWYDNENSYTSQMVRTIKYF 353 >2PKQ-O nrPDB Length = 368 Score = 458 bits (1178), Expect = e-129, Method: Composition-based stats. Identities = 154/339 (45%), Positives = 207/339 (61%), Gaps = 9/339 (2%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNS--GKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 K+KV +NGFGRIGR R +D+V +ND + ++ +YDS G F V Sbjct: 1 KLKVAINGFGRIGRNFLRCWHGRKDSPLDVVVVNDS-GGVKSATHLLKYDSILGTFKADV 59 Query: 61 KA-ENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRV 119 K +N I+G PI + RDP K+ W + G + V+E TGVF AG H+Q GAK+V Sbjct: 60 KIIDNETFSIDGKPIKVVSNRDPLKLPWAELGIDIVIEGTGVFVDGPGAGKHIQAGAKKV 119 Query: 120 IISAPSA--DAPMFVMGVNHEKYDNSL-KIISNASCTTNCLAPLAKVIHDNFGIVEGLMT 176 II+AP+ D P +V+GVN + Y + + IISNASCTTNCLAP KV+ + GIV+G MT Sbjct: 120 IITAPAKGSDIPTYVVGVNEKDYGHDVANIISNASCTTNCLAPFVKVLDEELGIVKGTMT 179 Query: 177 TVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVP 236 T H+ T Q+ +D L R A NI+P STGAAKAV V+P+L GKL G+A RVP Sbjct: 180 TTHSYTGDQRLLDASHRDLR-RARAAALNIVPTSTGAAKAVSLVLPQLKGKLNGIALRVP 238 Query: 237 TANVSVVDLTCRLEK-PAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTF 295 T NVSVVDL +EK +D+ ++A+ GPLKG+L + +VS DF SST Sbjct: 239 TPNVSVVDLVVNIEKVGVTAEDVNNAFRKAAAGPLKGVLDVCDIPLVSVDFRCSDFSSTI 298 Query: 296 DAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASK 334 D+ + + VK+++WYDNE+GYS RVVDL +A+K Sbjct: 299 DSSLTMVMGGDMVKVVAWYDNEWGYSQRVVDLADLVANK 337 >6IQV-A nrPDB Length = 340 Score = 457 bits (1176), Expect = e-129, Method: Composition-based stats. Identities = 141/341 (41%), Positives = 196/341 (57%), Gaps = 13/341 (3%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHG 58 VK+G+NGFGRIGRL R G +++VAIND + ++ +YDSTHG + Sbjct: 2 SVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAIND-LTSPALLAHLLKYDSTHGTLNA 60 Query: 59 TVKAENGKLVINGNPITIFQERDPSKIKW-GDAGAEYVVESTGVFTTMEKAGAHLQGGAK 117 V A + +V+NG ++ E I W + G ++V+E TG +T+ K+ AHL GAK Sbjct: 61 DVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAK 120 Query: 118 RVIISAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMT 176 RV+ISAP+ D V VN + +I+S SCTTNCLAPLA + FGI G MT Sbjct: 121 RVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMT 180 Query: 177 TVHAITATQKTVDGP-SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRV 235 T+HA T+TQ +DGP G +R R A N IP STGAAKA+G VIPELNGKL G A RV Sbjct: 181 TIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRV 240 Query: 236 PTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTF 295 + S+ +L L+K D++ +K+ +EG GY + ++VSSD T S F Sbjct: 241 GVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNES--FGYNDDEIVSSDVIGTTFGSIF 298 Query: 296 DAGAGIALND---HFVKLISWYDNEFGYSNRVVDLMAHMAS 333 D +D VK ++WYDNE+G++ ++V + A+ Sbjct: 299 DPTQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFAT 339 >3RVD-A nrPDB Length = 337 Score = 452 bits (1164), Expect = e-128, Method: Composition-based stats. Identities = 150/336 (44%), Positives = 203/336 (60%), Gaps = 6/336 (1%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNS--GKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 K+KV +NGFGRIGR R +DI+AIND + ++ +YDST G F Sbjct: 1 AKLKVAINGFGRIGRNFLRCWHGRKDSPLDIIAINDT-GGVKQASHLLKYDSTLGIFDAD 59 Query: 60 VKAENGK-LVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKR 118 VK + ++G I + R+PS + W + G + V+E TGVF E AG H++ GAK+ Sbjct: 60 VKPSGETAISVDGKIIQVVSNRNPSLLPWKELGIDIVIEGTGVFVDREGAGKHIEAGAKK 119 Query: 119 VIISAPS-ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTT 177 VII+AP D P +V+GVN + Y + IISNASCTTNCLAP KV+ FGI++G MTT Sbjct: 120 VIITAPGKGDIPTYVVGVNADAYSHDEPIISNASCTTNCLAPFVKVLDQKFGIIKGTMTT 179 Query: 178 VHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPT 237 H+ T Q+ +D L R A NI+P STGAAKAV V+P L GKL G+A RVPT Sbjct: 180 THSYTGDQRLLDASHRDLR-RARAAALNIVPTSTGAAKAVALVLPNLKGKLNGIALRVPT 238 Query: 238 ANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDA 297 NVSVVDL ++ K +++ + ++E LKGIL + +VS DF S+T D+ Sbjct: 239 PNVSVVDLVVQVSKKTFAEEVNAAFRDSAEKELKGILDVCDEPLVSVDFRCSDFSTTIDS 298 Query: 298 GAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + + D VK+I+WYDNE+GYS RVVDL +A+ Sbjct: 299 SLTMVMGDDMVKVIAWYDNEWGYSQRVVDLADIVAN 334 >2XF8-A nrPDB Length = 338 Score = 450 bits (1159), Expect = e-127, Method: Composition-based stats. Identities = 124/335 (37%), Positives = 199/335 (59%), Gaps = 7/335 (2%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG---KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 60 V+V +NGFGRIGR V RA + SG ++ +VAIN+ D M ++ +YD++HG+F V Sbjct: 2 VRVAINGFGRIGRNVVRALYESGRRAEITVVAINE-LADAAGMAHLLKYDTSHGRFAWEV 60 Query: 61 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 120 + E +L + + I + ER + W + G + V++ TGV+ + E AH+ GAK+V+ Sbjct: 61 RQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVL 120 Query: 121 ISAPSADA--PMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTV 178 S P ++ V GVN ++ +I+SNASCTTNC+ P+ K++ D +GI G +TT+ Sbjct: 121 FSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTI 180 Query: 179 HAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTA 238 H+ Q+ +D L R R A Q+IIP T A + + P+ N + +A RVPT Sbjct: 181 HSAMHDQQVIDAYHPDL-RRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTI 239 Query: 239 NVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAG 298 NV+ +DL+ ++KP K +++ ++++A++G GI+ YTE +VS DFN D HS+ D Sbjct: 240 NVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGT 299 Query: 299 AGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 H +K + W DNE+G++NR++D MA+ Sbjct: 300 QTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAT 334 >5J9G-A nrPDB Length = 338 Score = 443 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 137/340 (40%), Positives = 189/340 (55%), Gaps = 15/340 (4%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSG----KVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 VK+G+NGFGRIGRL R + G +++VAIND + ++ +YDSTHG F Sbjct: 3 VKIGINGFGRIGRLAFRRIMDLGEKSKDIEVVAIND-LTTPALLAHLLKYDSTHGTFDHE 61 Query: 60 VKAENGKLVINGNPITIFQERDPSKIKW-GDAGAEYVVESTGVFTTMEKAGAHLQGGAKR 118 V + +V++G ++ E I W + G ++V+E TG +T+ K+ AHL G KR Sbjct: 62 VSSTEDSIVVDGKKYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGVKR 121 Query: 119 VIISAPSA-DAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTT 177 V+ISAP+ D V VN + KI+S SCTTN LAP+ + FGI G MTT Sbjct: 122 VLISAPAGNDLKTIVYSVNQDTLTADDKIVSAGSCTTNSLAPMVNALQKEFGIEVGTMTT 181 Query: 178 VHAITATQKTVDGP-SGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVP 236 +HA T+TQ +DGP G R R A NIIP STGAAKA+G VIPELNGKL G A RVP Sbjct: 182 IHAYTSTQMILDGPVRGGNLRAARAAAINIIPHSTGAAKAIGLVIPELNGKLNGHAQRVP 241 Query: 237 TANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFD 296 + SV +L L K D++ + +K+ Y + VVSSD T S FD Sbjct: 242 VPDGSVTELVSILGKNVTADEVNEAMKKYESPS----FEYEPNNVVSSDILGRTAGSIFD 297 Query: 297 AGAGIAL---NDHFVKLISWYDNEFGYSNRVVDLMAHMAS 333 + + VK ++WYDNE+ ++ ++V + H A+ Sbjct: 298 PTQTMVTTAGDKQLVKTVAWYDNEYSFTCQMVRTLLHFAT 337 >3TZ6-A nrPDB Length = 344 Score = 154 bits (389), Expect = 5e-38, Method: Composition-based stats. Identities = 50/200 (25%), Positives = 84/200 (42%), Gaps = 32/200 (16%) Query: 49 YDSTHGKFHGTVKAENGKLVINGNPITI--FQERDPSKIKWGDAGAEYVVESTGVFTTME 106 + ++ +F + +++ KL G I + + DPS G + + S G + M Sbjct: 26 FPASAVRFFASARSQGRKLAFRGQEIEVEDAETADPS-------GLDIALFSAG--SAMS 76 Query: 107 KAGAHLQGGAKRVIISAPSA-----DAPMFVMGVNHEK--YDNSLKIISNASCTTNCLAP 159 K A A +I SA D P+ V VN E+ + II+N +CTT P Sbjct: 77 KVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRRPKGIIANPNCTTMAAMP 136 Query: 160 LAKVIHDNFGIVEGLMTTVHAITAT-----------QKTVDGPSGKLWRDGRGALQNIIP 208 + KV+HD +V ++++ A++ + + V G + +L DG P Sbjct: 137 VLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGGAEQLVYDG--GALEFPP 194 Query: 209 ASTGAAKAVGKVIPELNGKL 228 +T A V+P L G L Sbjct: 195 PNTYVAPIAFNVVP-LAGSL 213 >2YV3-A nrPDB Length = 331 Score = 81.0 bits (199), Expect = 6e-16, Method: Composition-based stats. Identities = 51/246 (20%), Positives = 93/246 (37%), Gaps = 37/246 (15%) Query: 49 YDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKA 108 + + + + + ++ +L G I + + G + V+ S G + KA Sbjct: 25 FPLSELRLYASPRSAGVRLAFRGEEIPV------EPLPEGPLPVDLVLASAGGGISRAKA 78 Query: 109 GAHLQGGAKRVIISAPSAD-----APMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKV 163 +GGA +++ SA P+ V VN EK II+N +CTT LA Sbjct: 79 LVWAEGGA--LVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGIIANPNCTTAILAMALWP 136 Query: 164 IHDNFGIVEGLMTTVHAITA------------TQKTVDGPSGKLWRDGRGALQNIIPA-- 209 +H F ++ T A + T + + G + K N+IP Sbjct: 137 LHRAFQAKRVIVATYQAASGAGAKAMEELLTETHRFLHGEAPKAEAFAHPLPFNVIPHID 196 Query: 210 ---STGAAKAVGKVIPELNG-------KLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIK 259 G + KV+ E + +++ A RVPT ++ +P + + Sbjct: 197 AFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAEAVSVEFARPVTPEAAR 256 Query: 260 KVVKQA 265 +V+K+A Sbjct: 257 EVLKEA 262 >2R00-A nrPDB Length = 336 Score = 75.6 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 36/177 (20%), Positives = 65/177 (36%), Gaps = 20/177 (11%) Query: 58 GTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAK 117 + ++E NG + + ++ + W + S G + A + A Sbjct: 37 ASERSEGKTYRFNGKTVRV---QNVEEFDWSQ--VHIALFSAG--GELSAKWAPIAAEAG 89 Query: 118 RVIISAPSA-----DAPMFVMGVNHEKYD--NSLKIISNASCTTNCLAPLAKVIHDNFGI 170 V+I S D P+ V VN E + II+N +C+T + K I+D GI Sbjct: 90 VVVIDNTSHFRYDYDIPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMLVALKPIYDAVGI 149 Query: 171 VEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIP--ASTGAAKAVGKVIPELN 225 +TT +++ K L N P +T + + IP+++ Sbjct: 150 ERINVTTYQSVSGAGKAGI----DELAGQTAKLLNGYPAETNTFSQQIAFNCIPQID 202 >3PWS-A nrPDB Length = 366 Score = 67.2 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 55/134 (41%), Gaps = 12/134 (8%) Query: 55 KFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQG 114 ++ + ++ L ITI + + + G + + S G T+ + A ++ Sbjct: 33 RYLASARSAGKSLKFKDQDITIEETTETAF-----EGVDIALFSAGSSTSAKYAPYAVKA 87 Query: 115 GAKRVIISAPS-----ADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFG 169 G V++ S D P+ V VN D II+ +C+T + + + +G Sbjct: 88 G--VVVVDNTSYFRQNPDVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWG 145 Query: 170 IVEGLMTTVHAITA 183 + +++T A++ Sbjct: 146 LDRIIVSTYQAVSG 159 >1YS4-A nrPDB Length = 354 Score = 52.5 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 53/290 (18%), Positives = 107/290 (36%), Gaps = 52/290 (17%) Query: 3 KVKVGVNG-FGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVK 61 K+KVGV G G +G+ + + ++ A+ +Y Sbjct: 8 KIKVGVLGATGSVGQRFVQLLADHPMFELTALAASERSAGK-----KYK------DACYW 56 Query: 62 AENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII 121 ++ + N + + DP ++ D + V + + + + K ++I Sbjct: 57 FQDRDIPENIKDMVVIPT-DPKHEEFED--VDIVFSA--LPSDLAKKFEPEFAKEGKLIF 111 Query: 122 SAPSA-----DAPMFVMGVNHEKYDN----------SLKIISNASCTTNCLAPLAKVIHD 166 S SA D P+ + VN + + II+N +C+T C K I D Sbjct: 112 SNASAYRMEEDVPLVIPEVNADHLELIEIQREKRGWDGAIITNPNCSTICAVITLKPIMD 171 Query: 167 NFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIP--------ASTGAAKAVG 218 FG+ + T+ A++ +G L N+IP T + K +G Sbjct: 172 KFGLEAVFIATMQAVSG--------AGYNGVPSMAILDNLIPFIKNEEEKMQTESLKLLG 223 Query: 219 KV----IPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQ 264 + + N K++ RV + + + ++ A+ ++IK+V+ + Sbjct: 224 TLKDGKVELANFKISASCNRVAVIDGHTESIFVKTKEGAEPEEIKEVMDK 273 >2CZC-A nrPDB Length = 334 Score = 46.7 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 57/265 (21%), Positives = 93/265 (35%), Gaps = 41/265 (15%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQ------YDSTHGKF 56 KVKVGVNG+G IG+ V A ++++ I ++ Y + Y ++ Sbjct: 2 KVKVGVNGYGTIGKRVAYAVTKQDDMELIGI--TKTKPDFEAYRAKELGIPVYAASEEFI 59 Query: 57 HGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVEST-GVFTTMEKAGAHLQGG 115 + E + G + ++ + +V++T G K + + G Sbjct: 60 P---RFEKEGFEVAGTLNDLLEK------------VDIIVDATPGGIGAKNK-PLYEKAG 103 Query: 116 AKRVIISAPSADAP--MFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEG 173 K + AD FV N+E + SC T L I + V Sbjct: 104 VKAIFQGGEKADVAEVSFVAQANYEAALG-KNYVRVVSCNTTGLVRTLSAIREYADYVYA 162 Query: 174 LMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAF 233 +M A K R A++ + + V VIP + MAF Sbjct: 163 VMIRRAADPNDTK----------RGPINAIKPTVEVPSHHGPDVQTVIPI---NIETMAF 209 Query: 234 RVPTANVSVVDLTCRLEKPAKYDDI 258 VPT + V + L+KP DD+ Sbjct: 210 VVPTTLMHVHSVMVELKKPLTKDDV 234 >1CF2-P nrPDB Length = 337 Score = 44.8 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 67/339 (19%), Positives = 108/339 (31%), Gaps = 64/339 (18%) Query: 6 VGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENG 65 V +NG+G +G+ V A + ++ ++ D + + + + V Sbjct: 4 VAINGYGTVGKRVADAIAQQDDMKVIGVSKTRPDFEARMALKK------GYDLYVAIPER 57 Query: 66 KLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPS 125 + I + D A+ V++ T GAK + + Sbjct: 58 VKLFEKAGIEVAGTVDDML-----DEADIVIDCT-----------PEGIGAKNLKMYKEK 101 Query: 126 ADAPMFVMGVNHEKYDNSLKIISN------------ASCTTNCLAPLAKVIHDNFGIVEG 173 +F G HE S +SN SC T L K +HD+FGI + Sbjct: 102 GIKAIFQGGEKHEDIGLSFNSLSNYEESYGKDYTRVVSCNTTGLCRTLKPLHDSFGIKKV 161 Query: 174 LMTTVHAITATQKTVDGPSGKLWRDGRGALQN-IIPASTGAAKAVG-KVIPELNGKLTGM 231 + V G N IIP G V L+ + M Sbjct: 162 ------------RAVIVRRGADPAQVSKGPINAIIPNPPKLPSHHGPDVKTVLDINIDTM 209 Query: 232 AFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTH 291 A VPT + ++ +E+ DDI V E + IL E + S+ + Sbjct: 210 AVIVPTTLMHQHNVMVEVEETPTVDDIIDVF----EDTPRVILISAEDGLTSTAEIME-- 263 Query: 292 SSTFDAGAGIALNDHFVKLISW------YDNEFGYSNRV 324 + G + ND ++ W DNE Y V Sbjct: 264 ---YAKELGRSRND-LFEIPVWRESITVVDNEIYYMQAV 298 >3HSK-A nrPDB Length = 381 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 43/174 (24%), Positives = 67/174 (38%), Gaps = 42/174 (24%) Query: 126 ADAPMFVMGVNHEKYDNSLKIISNAS-----------CTTNC-----LAPLAKVIHDNFG 169 D P+ V VN E D + A C +NC +APL K + + FG Sbjct: 131 KDVPLVVPIVNPEHIDVVENKVKQAVSKGGKKPGFIICISNCSTAGLVAPL-KPLVEKFG 189 Query: 170 IVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTG--------AAKAVGKV- 220 ++ L TT + G SG L NI+P +G K +G V Sbjct: 190 PIDALTTTTLQAISGAGFSPGVSGMDI------LDNIVPYISGEEDKLEWETKKILGGVN 243 Query: 221 --------IPELNGKLTGMAFRVPTANVSVVDLTCR-LEKPA-KYDDIKKVVKQ 264 IPE K++ RVP + ++ R +PA +D+K+ +++ Sbjct: 244 AEGTEFVPIPESEMKVSAQCNRVPVIDGHTECISLRFANRPAPSVEDVKQCLRE 297 >2EP5-A nrPDB Length = 350 Score = 39.8 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 37/174 (21%), Positives = 67/174 (38%), Gaps = 35/174 (20%) Query: 117 KRVIISAPSA-----DAPMFVMGVNHEKY---------DNSLKI-ISNASCTTNCLAPLA 161 ++++S S D P+ +N E I + N +CT ++ Sbjct: 101 GKIVVSNASPFRMDPDVPLINPEINWEHLELLKFQKERKGWKGILVKNPNCTAAIMSMPI 160 Query: 162 KVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVI 221 K + + + ++TT+ A++ G +G + G NIIP G + K + Sbjct: 161 KPLIEIATKSKIIITTLQAVSGA-----GYNGISFMAIEG---NIIPYIKGEEDKIAKEL 212 Query: 222 PELNGKL------------TGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVK 263 +LNGKL T + RVPT + + + ++IKK +K Sbjct: 213 TKLNGKLENNQIIPANLDSTVTSIRVPTRVGHMGVINIVTNERINIEEIKKTLK 266 >2YYY-A nrPDB Length = 343 Score = 39.0 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 55/281 (19%), Positives = 95/281 (33%), Gaps = 56/281 (19%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 KV +NG+G IG+ V A ++++ + D F + E Sbjct: 4 KVLINGYGSIGKRVADAVSMQDDMEVIGVTKTKPD----------------FEARLAVEK 47 Query: 65 G-KLVI---NGNPITIFQERD-PSKIKWGDA--GAEYVVESTGVFTTME---------KA 108 G KL + + + +F++ P + D A+ VV+ + K Sbjct: 48 GYKLFVAIPDNERVKLFEDAGIPVEGTILDIIEDADIVVDGAPKKIGKQNLENIYKPHKV 107 Query: 109 GAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDN-----SLKIISNASCTTNCLAPLAKV 163 A LQGG K + D N + + SC T L + Sbjct: 108 KAILQGGEK-------AKDV-----EDNFNALWSYNRCYGKDYVRVVSCNTTGLCRILYA 155 Query: 164 IHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPE 223 I+ I + + V ++ D P+ N + + V V+PE Sbjct: 156 INSIADIKKARIVLV------RRAAD-PNDDKTGPVNAITPNPVTVPSHHGPDVVSVVPE 208 Query: 224 LNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQ 264 GK+ A VPT + + L ++ DDI + +K+ Sbjct: 209 FEGKILTSAVIVPTTLMHMHTLMVEVDGDVSRDDILEAIKK 249 >3WYB-A nrPDB Length = 334 Score = 39.0 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 5/46 (10%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFI--DLNYMV 44 M K+++G+ G+G +GR V A + +++VA+ F D + Sbjct: 1 MSKIRIGIVGYGNLGRGVEAAIQQNPDMELVAV---FTRRDPKTVA 43 >6C8W-A nrPDB Length = 375 Score = 37.9 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 53/137 (38%), Gaps = 26/137 (18%) Query: 146 IISNASCTTNCLAPLAKVIHDNFG-IVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQ 204 I+ N++C L AK + FG I M T+ A++ G S D Sbjct: 148 IVCNSNCAVVGLVIPAKALIQKFGPIESVSMVTMQAVSGA--GYPGVSSMDIFD------ 199 Query: 205 NIIP--------ASTGAAKAVGKVIPELNGKLTGMAF-------RVPTANVSVVDLTCR- 248 NI+P +T + K +G + P+L G RVP + V + R Sbjct: 200 NIVPFIPGEEGKIATESRKILGNLNPDLAGFSDQQPLQVSVACNRVPVLDGHTVCASLRF 259 Query: 249 LEKPA-KYDDIKKVVKQ 264 + +PA ++ +++ Sbjct: 260 VNRPAPTASQVRDALRE 276 >3BIO-A nrPDB Length = 304 Score = 36.0 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAI 33 K++ + G+G IGR +A + +I I Sbjct: 9 KIRAAIVGYGNIGRYALQALREAPDFEIAGI 39 >5CEF-A nrPDB Length = 375 Score = 36.0 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 57/143 (39%), Gaps = 32/143 (22%) Query: 146 IISNASC-TTNCLAPLAKVIHDNFG-IVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAL 203 I++NA+C TT + PLA + FG + ++TT+ AI+ G S D Sbjct: 152 IVTNANCSTTGIVVPLA-ALEKAFGPLDTVIVTTLQAISGA--GYPGVSSLDIMD----- 203 Query: 204 QNIIPASTG--------AAKAVGKVIPELNGKLTGMA----------FRVPTANVSVVDL 245 N++P +G K +G V P+ N A RVP + + Sbjct: 204 -NVVPLISGEEDKIEWETNKILGGVTPD-NKAFDLHAPKQINVSATCTRVPVIDGHTGCV 261 Query: 246 TCRLEK--PAKYDDIKKVVKQAS 266 + + + P +++ ++ + Sbjct: 262 SVKFARSPPPSVAEVENAFREYT 284 >2DC1-A nrPDB Length = 236 Score = 34.4 bits (78), Expect = 0.063, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 38/101 (37%), Gaps = 14/101 (13%) Query: 6 VGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENG 65 VG+ G+G IG+ +I AI D + MV G + Sbjct: 3 VGLIGYGAIGK-FLAEWLERNGFEIAAILDVRGEHEKMV------------RGIDEFLQR 49 Query: 66 KLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTME 106 ++ + + +D ++ K AG + +V STG F + Sbjct: 50 EMDVAVEAASQQAVKDYAE-KILKAGIDLIVLSTGAFADRD 89 >3AOE-A nrPDB Length = 424 Score = 34.4 bits (78), Expect = 0.067, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 2/58 (3%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDST-HGKFHGTVK 61 +V + GFG +G RA + G +VA+ D + + YD H + G V+ Sbjct: 221 RVAIQGFGNVGNAAARAFHDHGA-RVVAVQDHTGTVYNEAGIDPYDLLRHVQEFGGVR 277 >3WGO-A nrPDB Length = 326 Score = 34.0 bits (77), Expect = 0.090, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 21/32 (65%) Query: 2 GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAI 33 K+++G+ G+G IG+ V +A + +++ AI Sbjct: 3 SKIRIGIVGYGNIGKGVEKAIKQNDDMELEAI 34 >3DAP-A nrPDB Length = 320 Score = 33.6 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 18/33 (54%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAI 33 M ++V + G+G +GR V + +D+V I Sbjct: 1 MTNIRVAIVGYGNLGRSVEKLIAKQPDMDLVGI 33 >4ZHS-D nrPDB Length = 379 Score = 33.6 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 60/167 (35%), Gaps = 39/167 (23%) Query: 128 APMFVMGVN------------HEKYDNSLKIISNASCTTNCLAPLAKVIHDNFG-IVEGL 174 P+ V VN H D + ++ N++C L AK + FG I Sbjct: 136 VPLVVPLVNAGHIDVIPAQRKHFGLDKGM-LVCNSNCAVVGLVVPAKALIQKFGPIESVS 194 Query: 175 MTTVHAITATQKTVDGPSGKLWRDGRGALQNIIP--------ASTGAAKAVGKVIPELNG 226 M T+ A++ G S D NI+P S+ A K +G + +L G Sbjct: 195 MVTMQAVSGA--GYPGVSSMDIFD------NIVPYIPGEEGKISSEARKILGDLNSDLAG 246 Query: 227 -------KLTGMAFRVPTANVSVV--DLTCRLEKPAKYDDIKKVVKQ 264 +++ RVP + V L P +++ +++ Sbjct: 247 FSDQKPLQISVACNRVPVLDGHTVCASLRFVNRPPPTASQVREALRE 293 >3WBB-A nrPDB Length = 305 Score = 32.9 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 19/33 (57%) Query: 1 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAI 33 M K++V V G+G +GR A + +++V + Sbjct: 7 MDKLRVAVVGYGNVGRYALEAVQAAPDMELVGV 39 >3MH6-A nrPDB Length = 456 Score = 32.1 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 34/143 (23%), Positives = 54/143 (37%), Gaps = 34/143 (23%) Query: 171 VEGLM-TTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKA---VGKVIPELNG 226 G+M T +++ A VD RGA + + ++ AAKA G VI LNG Sbjct: 264 ELGIMGTELNSELAKAMKVDA--------QRGAFVSQVLPNSSAAKAGIKAGDVITSLNG 315 Query: 227 KLTGM--AFRVPTANVSV-VDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVS 283 K A R + V LT L + K ++ ++Q+S+ Sbjct: 316 KPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQ---------------- 359 Query: 284 SDFNSDTHSSTFDAGAGIALNDH 306 N SS F+ G +++ Sbjct: 360 ---NQVDSSSIFNGIEGAEMSNK 379 >1B7G-O nrPDB Length = 340 Score = 31.7 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 2/43 (4%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYM 46 V V VNG+G IG+ V A + +V + NY ++ Sbjct: 2 VNVAVNGYGTIGKRVADAIIKQPDMKLVGV--AKTSPNYEAFI 42 >5VM2-A nrPDB Length = 347 Score = 31.3 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 29/144 (20%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAEN 64 K+ + G G IG + +A G +I A+ D M Sbjct: 171 KIIILGAGCIGLMTLQACKCLGATEI-AVVDVLEKRLAMAEQL----------------G 213 Query: 65 GKLVING-NPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVII-S 122 +VING TI + + ++ D GA+ V E+ G T+++A + G K +I+ + Sbjct: 214 ATVVINGAKEDTIARCQQFTE----DMGADIVFETAGSAVTVKQAPYLVMRGGKIMIVGT 269 Query: 123 APSADAPMFVMGVNHEKYDNSLKI 146 P A A +N K + + I Sbjct: 270 VPGASA------INFLKINREVTI 287 >3GIX-A nrPDB Length = 149 Score = 31.3 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 21/72 (29%), Gaps = 10/72 (13%) Query: 246 TCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQV----------VSSDFNSDTHSSTF 295 + L K ++ + +K +E L G E V SSD + Sbjct: 2 SFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLV 61 Query: 296 DAGAGIALNDHF 307 D +F Sbjct: 62 DVDQTAVYTQYF 73 >3DC2-A nrPDB Length = 529 Score = 30.2 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 47/139 (33%), Gaps = 26/139 (18%) Query: 6 VGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENG 65 VGV G GRIG+LV + G +VA DP++ + G Sbjct: 145 VGVVGLGRIGQLVAQRIAAFGAY-VVAY-DPYVSPARAAQL-----------GIELLSLD 191 Query: 66 KLVINGNPITIFQERDPSK--------IKWGDAGAEYVVESTGVFTTMEK-----AGAHL 112 L+ + I++ + P + G V + G G H+ Sbjct: 192 DLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHV 251 Query: 113 QGGAKRVIISAPSADAPMF 131 + V + P D+P+F Sbjct: 252 RAAGLDVFATEPCTDSPLF 270 >4F3Y-A nrPDB Length = 272 Score = 29.8 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 45/134 (33%), Gaps = 26/134 (19%) Query: 1 MGKVKVGVNGF-GRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGT 59 M +K+ + G GR+GR++ A + +V D G+ G Sbjct: 5 MSSMKIAIAGASGRMGRMLIEAVLAAPDATLVGALDRTGSPQL-----------GQDAGA 53 Query: 60 VKAENGKLVINGNPITIFQERDPS---KIKWGDA---------GAEYVVESTGVFTTMEK 107 + + + + + E D + G + V+ +TG F+ +K Sbjct: 54 FLGKQTGVALTDDIERVCAEADYLIDFTLPEGTLVHLDAALRHDVKLVIGTTG-FSEPQK 112 Query: 108 AGAHLQGGAKRVII 121 A G K ++ Sbjct: 113 AQL-RAAGEKIALV 125 >3L9X-A nrPDB Length = 413 Score = 29.8 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDP 36 ++V + GFGR G++ R +SG +V +DP Sbjct: 5 MRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDP 37 >4WOJ-A nrPDB Length = 370 Score = 29.8 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%) Query: 229 TGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASE 267 G+ RVP+ LT +L + ++IK+ + Q +E Sbjct: 264 DGICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNE 302 >6IGZ-L nrPDB Length = 204 Score = 29.8 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 13/75 (17%) Query: 213 AAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKG 272 A VG V GKL GM R P + S+ + R D+ K+V++ + P G Sbjct: 10 AKPLVGSVF----GKLNGMTPRAPMRSRSIT-VVVRA-----ADEQKQVIQPINGDPFIG 59 Query: 273 ILGYTEHQVVSSDFN 287 +L E V S+ Sbjct: 60 ML---ETPVTSAPIV 71 >3EUW-A nrPDB Length = 344 Score = 29.4 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 21/36 (58%) Query: 4 VKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFID 39 +++ + G GRIG + + +++V I DPFI+ Sbjct: 5 LRIALFGAGRIGHVHAANIAANPDLELVVIADPFIE 40 >3EC7-A nrPDB Length = 357 Score = 29.4 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 21/47 (44%), Gaps = 2/47 (4%) Query: 4 VKVGVNGFGRIGRLVTRAAFNS-GKVDIVAINDPFIDLNYMVYMFQY 49 +K G+ G G IG R N+ V++VA+ D + +Y Sbjct: 24 LKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAA-LDKY 69 >5G1T-A nrPDB Length = 256 Score = 29.4 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 5/68 (7%) Query: 72 NPITIFQERDPS--KIKWGD---AGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSA 126 + + + +DP+ +I AG V+ G T E A L+ G RV+I + + Sbjct: 50 HLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEEDVAALLKAGVARVVIGSTAV 109 Query: 127 DAPMFVMG 134 +P V G Sbjct: 110 KSPDVVKG 117 >1W9M-A nrPDB Length = 553 Score = 29.0 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 22/59 (37%), Gaps = 5/59 (8%) Query: 153 TTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSG--KLWRDGRGALQNIIPA 209 TTNCL PL K +N + T V + D P+G K + + P Sbjct: 309 TTNCLVPLKK---ENTYLDRLYTTGVVGYEGAKHIADRPAGGAKDFSALIAQAKKCPPP 364 >4XEB-A nrPDB Length = 436 Score = 29.0 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 17/37 (45%), Gaps = 3/37 (8%) Query: 148 SNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITAT 184 S SCTTN A + N+ V G+ T+ + T Sbjct: 21 SGGSCTTNSGA---ITLDANWRWVHGVNTSTNCYTGN 54 >3PAJ-A nrPDB Length = 320 Score = 29.0 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 187 TVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNG 226 T+ GP+ L R A N I +G A A + + EL G Sbjct: 128 TLTGPARILLTGERNA-MNFIQTLSGCATATARYVQELKG 166 >5AOV-A nrPDB Length = 336 Score = 28.6 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 9/17 (52%), Positives = 13/17 (76%) Query: 6 VGVNGFGRIGRLVTRAA 22 +G+ GFGRIG+ + R A Sbjct: 153 IGIVGFGRIGQAIARRA 169 >6DLD-B nrPDB Length = 304 Score = 28.6 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 26/64 (40%) Query: 107 KAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHD 166 K L G + +II S + + V V E + N + +N TTN PL Sbjct: 233 KGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTA 292 Query: 167 NFGI 170 +GI Sbjct: 293 QYGI 296 >1IWP-B nrPDB Length = 194 Score = 28.6 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 12/31 (38%) Query: 14 IGRLVTRAAFNSGKVDIVAINDPFIDLNYMV 44 IG+ R A + +ND + +M Sbjct: 135 IGKNAARYARKESPSPVPVVNDQMVRPKFMA 165 >1XDW-A nrPDB Length = 331 Score = 28.6 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 19/84 (22%) Query: 6 VGVNGFGRIGRLVTRAAFNSGK-------VDIVAINDPFIDLNYMVYMFQYD--STHGKF 56 VGV G GRIGR+ + G +I I D ++ + + D + H + Sbjct: 149 VGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKGIEDYCTQVSLDEVLEKSDIITIHAPY 208 Query: 57 ---HGTV-------KAENGKLVIN 70 +G V K ++G +++N Sbjct: 209 IKENGAVVTRDFLKKMKDGAILVN 232 >4BI9-A nrPDB Length = 454 Score = 28.3 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 5/49 (10%) Query: 164 IHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTG 212 +HD F I E LM A G +G L R G AL IP +TG Sbjct: 350 VHDCFTIAELLM-----YEALGIAEYGGAGALIRSGATALDGRIPVNTG 393 >6G1M-A nrPDB Length = 338 Score = 28.3 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 18/31 (58%) Query: 5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAIND 35 KVG+ GFG +G + + + + +V ++D Sbjct: 3 KVGIWGFGAMGSGIAKNILSKKNLKLVGVHD 33 >3M6I-A nrPDB Length = 363 Score = 28.3 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 68 VINGNPITIFQERDPSKIKWGDAGAE--YVVESTGVFTTMEKAGAHLQGGAKRVII 121 V+ + E KI G E +E TGV +++ A ++ G K +I Sbjct: 227 VVTHKVERLSAEESAKKIVESFGGIEPAVALECTGVESSIAAAIWAVKFGGKVFVI 282 >2HAE-A nrPDB Length = 386 Score = 28.3 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 8/44 (18%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAI--------NDPFI 38 +VKV VNG G G + + + G ++VA+ NDP Sbjct: 182 EVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNENDPET 225 >3L6G-A nrPDB Length = 256 Score = 27.9 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 215 KAVGKVIPELNGKLTGMAFRVPT-ANV-SVVDLTCRLEKPAKYDDIKKVVKQASEGPL 270 K+V + P L G G F VP+ NV S+ DLT + K + V ASE L Sbjct: 72 KSVDLLGPNLKGAKVG--FVVPSYMNVNSIEDLTNQANKTITGIEPGAGVMAASEKTL 127 >1B26-A nrPDB Length = 416 Score = 27.9 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 21/58 (36%), Gaps = 5/58 (8%) Query: 3 KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDP---FIDLNYM--VYMFQYDSTHGK 55 K V V GFG +G+ +VA++D + + +Y HG Sbjct: 210 KATVAVQGFGNVGQFAALLISQELGSKVVAVSDSRGGIYNPEGFDVEELIRYKKEHGT 267 >5J5Z-A nrPDB Length = 496 Score = 27.5 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 38/114 (33%), Gaps = 16/114 (14%) Query: 16 RLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDST-----HGKFHGT-----VKAENG 65 RL + A+ + ++F+ + +GK G KA+ G Sbjct: 104 RLNLDKMMEQKSTAVKAL------TGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGG 157 Query: 66 KLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRV 119 VI+ I I + + + +V STG + + + GA + Sbjct: 158 TQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVI 211 >4DPM-A nrPDB Length = 359 Score = 27.5 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 41/235 (17%), Positives = 82/235 (34%), Gaps = 51/235 (21%) Query: 120 IISAPS-----ADAPMFVMGVN--------HEKYDNSLK--IISNASCTTNCLA-PLAKV 163 +IS D P+ V +N ++ K I++ CT A PL + Sbjct: 106 VISNSPDHRFDPDVPLLVPELNPHTISLIDEQRKRREWKGFIVTTPLCTAQGAAIPLGAI 165 Query: 164 IHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTG----AAKAVGK 219 D + + +TT+ +++ PS + NI+P G K + + Sbjct: 166 FKD-YKMDGAFITTIQSLSG-AGYPGIPSLDVV-------DNILPLGDGYDAKTIKEIFR 216 Query: 220 VIPELN-----GKLTGMAF-----RVPTANVSVVDLTCRLEKPAKYDDIKKVVK------ 263 ++ E+ KL ++ R+ T + L ++ + +K+ ++ Sbjct: 217 ILSEVKRNVDEPKLEDVSLAATTHRIATIHGHYEVLYVSFKEETAAEKVKETLENFRGEP 276 Query: 264 ---QASEGPLKGILGYTEH--QVVSSD-FNSDTHSSTFDAGAGIALNDHFVKLIS 312 + P K I+ E V D + D + G +N ++L+S Sbjct: 277 QDLKLPTAPSKPIIVMNEDTRPQVYFDRWAGDIPGMSVVVGRLKQVNKRMIRLVS 331 >1I74-A nrPDB Length = 309 Score = 27.5 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 7/53 (13%) Query: 228 LTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQ--ASEGPLKGILGYTE 278 L G RV A V+ VD+ LE+ ++I++ +K A+ G +L T+ Sbjct: 209 LNGSQVRV--AQVNTVDINEVLERQ---NEIEEAIKASQAANGYSDFVLMITD 256 >2IIR-A nrPDB Length = 403 Score = 27.5 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 25/71 (35%), Gaps = 2/71 (2%) Query: 68 VINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSAD 127 +NG +F +E GV +K ++G K IIS P + Sbjct: 319 AMNGVDAIVFTAGVGENSPITREDVCSYLEFLGVKLDKQKNEETIRG--KEGIISTPDSR 376 Query: 128 APMFVMGVNHE 138 + V+ N E Sbjct: 377 VKVLVVPTNEE 387 >5CXX-A nrPDB Length = 275 Score = 27.1 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 155 NCLAPLAKVIHDNFGIV---EGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPAST 211 N + P+ + + +V GLM+ ++ T+ P+ L ++GR I+ Sbjct: 43 NVILPVGYDENKKYPVVYYLHGLMSYEDSMLEDDSTLAIPT-NLLKEGRAKEMIIVLPDV 101 Query: 212 GAAKAVGKVIPELN 225 A K V P+ N Sbjct: 102 YAPKPGTAVTPDFN 115 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.158 0.499 Lambda K H 0.267 0.0489 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,742,068 Number of Sequences: 36641 Number of extensions: 849142 Number of successful extensions: 2730 Number of sequences better than 10.0: 107 Number of HSP's better than 10.0 without gapping: 139 Number of HSP's successfully gapped in prelim test: 46 Number of HSP's that attempted gapping in prelim test: 2205 Number of HSP's gapped (non-prelim): 192 length of query: 335 length of database: 10,336,785 effective HSP length: 98 effective length of query: 237 effective length of database: 6,745,967 effective search space: 1598794179 effective search space used: 1598794179 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 60 (27.5 bits)