BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04147 (577 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6R5K-D nrPDB 1196 0.0 1IFW-A nrPDB 177 1e-44 6AH0-4 nrPDB 103 1e-22 1FXL-A nrPDB 89 5e-18 1FNX-H nrPDB 89 7e-18 5MMM-v nrPDB 86 5e-17 4EGL-A nrPDB 84 1e-16 3SXL-A nrPDB 84 2e-16 2CJK-A nrPDB 70 3e-12 5ZWM-4 nrPDB 67 2e-11 1P1T-A nrPDB 60 3e-09 2DH7-A nrPDB 59 7e-09 2DO0-A nrPDB 59 7e-09 2DH9-A nrPDB 58 1e-08 5ZWN-V nrPDB 57 2e-08 5EN1-A nrPDB 57 2e-08 1SXL-A nrPDB 57 2e-08 6GD1-A nrPDB 54 2e-07 6D0Y-A nrPDB 54 2e-07 3NNA-A nrPDB 53 4e-07 2MYF-A nrPDB 53 5e-07 6QX9-R nrPDB 52 5e-07 5EV3-A nrPDB 52 5e-07 2YWK-A nrPDB 52 6e-07 4LMZ-A nrPDB 52 1e-06 5OO6-B nrPDB 51 1e-06 5ZWM-X nrPDB 50 2e-06 2CQB-A nrPDB 50 2e-06 1X5O-A nrPDB 50 3e-06 1OO0-B nrPDB 50 4e-06 1D8Z-A nrPDB 50 4e-06 2KU7-A nrPDB 50 4e-06 5SZW-A nrPDB 49 5e-06 5MQF-o nrPDB 49 7e-06 1RK8-A nrPDB 49 7e-06 3MDF-A nrPDB 49 9e-06 2J0Q-D nrPDB 49 9e-06 1D9A-A nrPDB 48 9e-06 2ERR-A nrPDB 48 9e-06 2HYI-B nrPDB 48 1e-05 1P27-B nrPDB 48 1e-05 6ASO-A nrPDB 48 1e-05 3HI9-A nrPDB 48 1e-05 2SXL-A nrPDB 48 1e-05 4ZKA-A nrPDB 47 2e-05 3EX7-B nrPDB 47 2e-05 1H6K-X nrPDB 47 2e-05 4FXV-A nrPDB 47 2e-05 6FF4-1 nrPDB 47 2e-05 5YZG-w nrPDB 47 2e-05 1JH4-A nrPDB 45 8e-05 2CQ3-A nrPDB 45 9e-05 5ZWN-Q nrPDB 45 1e-04 6G90-B nrPDB 44 2e-04 2XS2-A nrPDB 44 2e-04 1G9L-A nrPDB 44 2e-04 2XS5-A nrPDB 44 2e-04 2CPD-A nrPDB 44 2e-04 2X04-A nrPDB 42 6e-04 6C8U-1 nrPDB 42 8e-04 1NMR-A nrPDB 42 9e-04 4WKR-A nrPDB 42 9e-04 3CW1-K nrPDB 41 0.001 2MGZ-B nrPDB 41 0.002 5X3Y-A nrPDB 41 0.002 6QX9-1K nrPDB 41 0.002 6H7A-A nrPDB 40 0.002 2LEC-A nrPDB 40 0.002 4PKD-B nrPDB 40 0.003 2KN4-A nrPDB 40 0.003 2CPE-A nrPDB 39 0.005 2DH8-A nrPDB 39 0.008 6FYY-r nrPDB 38 0.011 2DGS-A nrPDB 38 0.011 2RS2-A nrPDB 38 0.014 5YVG-X nrPDB 37 0.017 6QX9-1A nrPDB 37 0.019 2DYD-A nrPDB 37 0.025 1UAW-A nrPDB 37 0.028 5OSG-h nrPDB 36 0.035 1I2T-A nrPDB 36 0.046 2MKI-A nrPDB 36 0.053 2MST-A nrPDB 36 0.058 5OPT-h nrPDB 36 0.059 2MKK-A nrPDB 35 0.077 3N9U-C nrPDB 35 0.078 2RUG-A nrPDB 35 0.080 1X4A-A nrPDB 35 0.084 6EM1-o nrPDB 35 0.095 2I2Y-A nrPDB 35 0.095 2F9J-A nrPDB 35 0.11 1JMT-A nrPDB 34 0.15 2LCW-A nrPDB 34 0.19 2LA6-A nrPDB 33 0.27 3Q2T-C nrPDB 33 0.28 2DGQ-A nrPDB 33 0.30 2RT3-A nrPDB 33 0.30 3P6Y-C nrPDB 33 0.46 2I14-A nrPDB 33 0.50 6FYY-p nrPDB 32 0.75 3NS5-A nrPDB 32 1.1 5K1H-B nrPDB 31 1.1 3NNH-A nrPDB 31 1.1 2KVI-A nrPDB 31 1.2 2XNQ-A nrPDB 31 1.6 2CQH-A nrPDB 31 1.9 2KRB-A nrPDB 30 2.0 2M2B-A nrPDB 30 2.0 1WP5-A nrPDB 30 2.1 4QU7-A nrPDB 30 2.5 2NLW-A nrPDB 30 2.7 6ID0-O nrPDB 30 2.8 2MMY-A nrPDB 30 3.0 5ZJN-A nrPDB 30 3.1 4YH8-A nrPDB 29 4.4 5WU6-A nrPDB 29 4.6 2DGP-A nrPDB 29 6.4 5XYB-A nrPDB 29 6.5 6GIQ-d nrPDB 28 7.8 >6R5K-D nrPDB Length = 581 Score = 1196 bits (3093), Expect = 0.0, Method: Compositional matrix adjust. Identities = 577/577 (100%), Positives = 577/577 (100%) Query: 1 MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP 60 MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP Sbjct: 5 MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP 64 Query: 61 IGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 120 IGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL Sbjct: 65 IGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 124 Query: 121 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK Sbjct: 125 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 184 Query: 181 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 240 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA Sbjct: 185 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 244 Query: 241 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 300 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER Sbjct: 245 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 304 Query: 301 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK 360 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK Sbjct: 305 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK 364 Query: 361 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ 420 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ Sbjct: 365 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ 424 Query: 421 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGP 480 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGP Sbjct: 425 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGP 484 Query: 481 VYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQ 540 VYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQ Sbjct: 485 VYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQ 544 Query: 541 EVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA 577 EVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA Sbjct: 545 EVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA 581 >1IFW-A nrPDB Length = 92 Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 88/89 (98%), Positives = 88/89 (98%) Query: 489 GFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES 548 G PRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES Sbjct: 4 GSPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES 63 Query: 549 DELFEQHYKEASAAYESFKKEQEQQTEQA 577 DELFEQHYKEASAAYESFKKEQEQQTEQA Sbjct: 64 DELFEQHYKEASAAYESFKKEQEQQTEQA 92 >6AH0-4 nrPDB Length = 424 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 65/170 (38%), Positives = 94/170 (55%), Gaps = 3/170 (1%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 S N A++YVG L+ VSE L+++F G V + + +D +T GY +V F E Sbjct: 7 SERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEED 66 Query: 92 GRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGD 151 AI+ +N + G+ R+ + G+ NIFI NL P+ID K LYDTFS FG Sbjct: 67 ADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGA-NIFIGNLDPEIDEKLLYDTFSAFGV 125 Query: 152 IL-SSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA 199 IL + KI D + G SKG+ F++F A+ AI+A+NG L + I V+ Sbjct: 126 ILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS 175 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 55/188 (29%), Positives = 101/188 (53%), Gaps = 20/188 (10%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 +YV ++ + ++ ELF + GP+V+ + KD G+ +G+GFV + EDA A++ Sbjct: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK 337 +N +L G+ + V +A N+ + V G N+F+ NLD +D++ Sbjct: 73 IMNMIKLYGKPIRVNKASAHNKNLDV-----------------GANIFIGNLDPEIDEKL 115 Query: 338 LEEEFAPYGTIT-SAKVMR-TENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVA 395 L + F+ +G I + K+MR + G SKG+ F+ F++ + + AI N Q + +P+ V+ Sbjct: 116 LYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS 175 Query: 396 IAQRKDVR 403 A +KD + Sbjct: 176 YAFKKDSK 183 Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 44/177 (24%), Positives = 86/177 (48%), Gaps = 10/177 (5%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 +++ L + L++ F G ++++ + D G+ +G+GFV F E A AI Sbjct: 14 TVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKI 73 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPI 245 +N + L G+ I R + S + N+++ N++ E ++ + F+ FG I Sbjct: 74 MNMIKLYGKPI-------RVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVI 126 Query: 246 V-SASLEKDAD-GKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 300 + + + +D D G KG+ F+N+ + + A+EA+N L + V A KK+ + Sbjct: 127 LQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSK 183 >1FXL-A nrPDB Length = 167 Score = 89.0 bits (219), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 50/154 (32%), Positives = 84/154 (54%), Gaps = 3/154 (1%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 S +L V L ++++ +F IG + S ++ RD IT SLGY +VN+ D + KA Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 96 IEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSS 155 I LN ++ + ++ +++ PS N+++ L + K L FS +G I++S Sbjct: 61 INTLNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 118 Query: 156 KIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNG 188 +I D+ G S+G GF+ F++ A+EAI LNG Sbjct: 119 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 152 Score = 76.3 bits (186), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 57/183 (31%), Positives = 89/183 (48%), Gaps = 22/183 (12%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T E+F+ LF G I S L +D G+ G+GFVNY +DA KA+ Sbjct: 3 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 62 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK 337 LN L + + V A+ + A + NL+V L ++ ++ Sbjct: 63 TLNGLRLQTKTIKVSYARPSS------------------ASIRDANLYVSGLPKTMTQKE 104 Query: 338 LEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAG--KPLYV 394 LE+ F+ YG I +++++ + G S+G GF+ F EA +AI N Q +G +P+ V Sbjct: 105 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 164 Query: 395 AIA 397 A Sbjct: 165 KFA 167 Score = 71.6 bits (174), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 47/165 (28%), Positives = 88/165 (53%), Gaps = 16/165 (9%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 N+ + L ++ + F G+I S K+ D+ G+S G+GFV++ + A++AI+ Sbjct: 4 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 63 Query: 186 LNGMLLNGQEI---YVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF 242 LNG+ L + I Y P S RD+ NLYV + T ++ ++LF+++ Sbjct: 64 LNGLRLQTKTIKVSYARPS-SASIRDA----------NLYVSGLPKTMTQKELEQLFSQY 112 Query: 243 GPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNG 286 G I+++ + D G +G GF+ ++K +A +A++ LN + +G Sbjct: 113 GRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 157 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 NL V L ++ E+ F G I S K++R + G+S G+GFV + P++A KAI Sbjct: 4 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 63 Query: 382 KNQQIVAGKPLYVAIAQ 398 N + K + V+ A+ Sbjct: 64 LNGLRLQTKTIKVSYAR 80 >1FNX-H nrPDB Length = 174 Score = 88.6 bits (218), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 49/155 (31%), Positives = 85/155 (54%), Gaps = 3/155 (1%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 +S +L V L ++++ +F IG + S ++ RD IT SLGY +VN++D K Sbjct: 2 DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADK 61 Query: 95 AIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS 154 AI LN ++ + ++ +++ PS N+++ L + K + FS +G I++ Sbjct: 62 AINTLNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIIT 119 Query: 155 SKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNG 188 S+I D+ G S+G GF+ F++ A+EAI LNG Sbjct: 120 SRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNG 154 Score = 76.3 bits (186), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 55/183 (30%), Positives = 89/183 (48%), Gaps = 22/183 (12%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++F+ LF G I S L +D G+ G+GFVNY DA KA+ Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK 337 LN +L + + V A+ + A + NL+V L ++ ++ Sbjct: 65 TLNGLKLQTKTIKVSYARPSS------------------ASIRDANLYVSGLPKTMSQKE 106 Query: 338 LEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQ--IVAGKPLYV 394 +E+ F+ YG I +++++ + G S+G GF+ F EA +AI N Q + A +P+ V Sbjct: 107 MEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITV 166 Query: 395 AIA 397 A Sbjct: 167 KFA 169 Score = 72.0 bits (175), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 47/159 (29%), Positives = 84/159 (52%), Gaps = 16/159 (10%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 N+ + L ++ F GDI S K+ D+ G+S G+GFV++ + A +AI+ Sbjct: 6 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 65 Query: 186 LNGMLLNGQEI---YVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF 242 LNG+ L + I Y P S RD+ NLYV + + ++ ++LF+++ Sbjct: 66 LNGLKLQTKTIKVSYARPS-SASIRDA----------NLYVSGLPKTMSQKEMEQLFSQY 114 Query: 243 GPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALN 280 G I+++ + D A G +G GF+ ++K +A +A++ LN Sbjct: 115 GRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLN 153 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 NL V L ++ ++ + F G I S K++R + G+S G+GFV +S P +A KAI Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 381 EKNQQIVAGKPLYVAIAQ 398 N + K + V+ A+ Sbjct: 65 TLNGLKLQTKTIKVSYAR 82 >5MMM-v nrPDB Length = 260 Score = 85.9 bits (211), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 59/176 (33%), Positives = 93/176 (52%), Gaps = 6/176 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 LYV NI +++ + + + G I A + D G+ + FGFV + EDA +E L Sbjct: 86 LYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIEKL 145 Query: 280 NDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLE 339 ND+E+ G K+ V +K E M + Q E + + + Y+ +++ NL +V +E L+ Sbjct: 146 NDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVE-SPYK---VYIGNLAKTVTNELLK 201 Query: 340 EEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYV 394 + F+ G + AKV RT KS GFGFV FS+ EE AI N ++ G+ + V Sbjct: 202 DFFSEKGKVLGAKVQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRV 257 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 48/183 (26%), Positives = 94/183 (51%), Gaps = 14/183 (7%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKE 181 +G+ +++ N+ +++N L G I +++ D+ +G+S+ FGFV + A Sbjct: 81 EGARRLYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANA 140 Query: 182 AIDALNGMLLNGQEIYV---------APHLSRKERDSQLEETKAHYTNLYVKNINSETTD 232 I+ LN + G++I V + + DSQ E+ +Y+ N+ T+ Sbjct: 141 VIEKLNDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVESPYK---VYIGNLAKTVTN 197 Query: 233 EQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYV 291 E ++ F++ G ++ A +++ K GFGFV++ E+ A++ALN+S L G+K+ V Sbjct: 198 ELLKDFFSEKGKVLGAKVQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRV 257 Query: 292 GRA 294 +A Sbjct: 258 NKA 260 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 6/104 (5%) Query: 8 TAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSI 67 T + LE ++I Q + +SQ VE S +Y+G+L +V+ L D FS G V Sbjct: 160 TEKPLEGMDIATTQAE-----DSQFVE-SPYKVYIGNLAKTVTNELLKDFFSEKGKVLGA 213 Query: 68 RVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRI 111 +V R T S G+ +V+F+ E AI+ LN + ++G+ R+ Sbjct: 214 KVQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRV 257 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEK 382 L+V N+ ++++++L +G I A+VM + +G+S+ FGFV T E+A I + Sbjct: 86 LYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIEKL 145 Query: 383 NQQIVAGKPLYVAIAQR 399 N + G+ + V I ++ Sbjct: 146 NDTEIGGRKIKVNITEK 162 >4EGL-A nrPDB Length = 177 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 47/152 (30%), Positives = 83/152 (54%), Gaps = 3/152 (1%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 3 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 62 Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKI 157 LN ++ + ++ +++ PS N++I L + K + D FS FG I++S++ Sbjct: 63 TLNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRV 120 Query: 158 ATDE-NGKSKGFGFVHFEEEGAAKEAIDALNG 188 D+ G S+G F+ F++ A+EAI + NG Sbjct: 121 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 152 Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 20/167 (11%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++ + LF+ G + SA L +D G G+GFVNY +DA +A+ Sbjct: 3 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 62 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK 337 LN L + + V A+ +E V+K NL++ L ++ + Sbjct: 63 TLNGLRLQSKTIKVSYARPSSE---VIKD---------------ANLYISGLPRTMTQKD 104 Query: 338 LEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKN 383 +E+ F+ +G I +++V+ + G S+G F+ F EA +AIT N Sbjct: 105 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFN 151 Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 14/161 (8%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 G N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ A Sbjct: 1 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 60 Query: 183 IDALNGMLLNGQEIYVAPHLSRKE--RDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 240 I+ LNG+ L + I V+ E +D+ NLY+ + T + +++F+ Sbjct: 61 INTLNGLRLQSKTIKVSYARPSSEVIKDA----------NLYISGLPRTMTQKDVEDMFS 110 Query: 241 KFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALN 280 +FG I+++ + D G +G F+ ++K +A +A+ + N Sbjct: 111 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFN 151 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%) Query: 4 ITDKTAEQ----LENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFS 59 +T K AE+ L L +Q + + S V A+LY+ L ++++ + D+FS Sbjct: 52 VTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKD-ANLYISGLPRTMTQKDVEDMFS 110 Query: 60 PIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLN 100 G + + RV D T S G A++ F+ +AI N Sbjct: 111 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFN 151 >3SXL-A nrPDB Length = 184 Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 52/157 (33%), Positives = 84/157 (53%), Gaps = 10/157 (6%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDA 185 N+ + L D+ ++ LY F G I + +I D + G S G+ FV F E ++ AI Sbjct: 16 NLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKV 75 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPI 245 LNG+ + + + V+ +R +S + TNLYV N+ TD+Q +F K+G I Sbjct: 76 LNGITVRNKRLKVS--YARPGGESIKD------TNLYVTNLPRTITDDQLDTIFGKYGSI 127 Query: 246 VSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALND 281 V ++ +D G+ +G FV Y K E+A +A+ ALN+ Sbjct: 128 VQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNN 164 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 55/197 (27%), Positives = 96/197 (48%), Gaps = 22/197 (11%) Query: 206 ERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFV 264 E D + + +A TNL V + + TD + LF GPI + + +D G G+ FV Sbjct: 2 ESDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFV 61 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNL 324 ++ D+ +A++ LN + ++L V A+ E + + NL Sbjct: 62 DFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESI------------------KDTNL 103 Query: 325 FVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKN 383 +V NL ++ D++L+ F YG+I ++R + G+ +G FV ++ EEA +AI+ N Sbjct: 104 YVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALN 163 Query: 384 QQIVAG--KPLYVAIAQ 398 I G +PL V +A+ Sbjct: 164 NVIPEGGSQPLSVRLAE 180 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 46/159 (28%), Positives = 83/159 (52%), Gaps = 3/159 (1%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 S+ +L V L +++ LY +F IG +++ R+ RD T S GYA+V+F ++A Sbjct: 13 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRA 72 Query: 96 IEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSS 155 I+ LN ++ + ++ +++ P N+++ NL I + L F +G I+ Sbjct: 73 IKVLNGITVRNKRLKVSYAR--PGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQK 130 Query: 156 KIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNG 193 I D+ G+ +G FV + + A+EAI ALN ++ G Sbjct: 131 NILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEG 169 >2CJK-A nrPDB Length = 167 Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 52/178 (29%), Positives = 88/178 (49%), Gaps = 13/178 (7%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKE 181 K S +FI L+ D L + F +G + KI D G+S+GFGF+ FE+ + E Sbjct: 1 KESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDE 60 Query: 182 AIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAK 241 + + +L+G+ I + R E+D ++V I + ++F+E F++ Sbjct: 61 VVKTQH--ILDGKVIDPKRAIPRDEQDKT--------GKIFVGGIGPDVRPKEFEEFFSQ 110 Query: 242 FGPIVSASLEKDAD-GKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 +G I+ A L D D G+ +GFGFV Y+ DAV V + K+ + RA+ ++ Sbjct: 111 WGTIIDAQLMLDKDTGQSRGFGFVTYDS-ADAVDRVCQNKFIDFKDRKIEIKRAEPRH 167 Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 44/164 (26%), Positives = 84/164 (51%), Gaps = 22/164 (13%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 +++ +N +TT++ +E F K+G + + KD A G+ +GFGF+++EK + V+ Sbjct: 6 MFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVK-- 63 Query: 280 NDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLE 339 L+G+ + RA ++E+ +K K +FV + V ++ E Sbjct: 64 TQHILDGKVIDPKRAIPRDEQ-------------DKTGK-----IFVGGIGPDVRPKEFE 105 Query: 340 EEFAPYGTITSAKVM-RTENGKSKGFGFVCFSTPEEATKAITEK 382 E F+ +GTI A++M + G+S+GFGFV + + + + K Sbjct: 106 EFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNK 149 Score = 58.5 bits (140), Expect = 8e-09, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 77/143 (53%), Gaps = 5/143 (3%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 S +++G L +E +L + F G+V+ +++ +D T S G+ +++F + + + Sbjct: 3 SCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVV 62 Query: 97 EQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSK 156 + + + G++ I + P + +G IF+ + PD+ K + FS +G I+ ++ Sbjct: 63 KTQHI--LDGKV--IDPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFEEFFSQWGTIIDAQ 118 Query: 157 IATDEN-GKSKGFGFVHFEEEGA 178 + D++ G+S+GFGFV ++ A Sbjct: 119 LMLDKDTGQSRGFGFVTYDSADA 141 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 3/72 (4%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKA 378 + +F+ L+ ++ L E F YGT+T K+M+ G+S+GFGF+ F P + Sbjct: 2 ESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEV 61 Query: 379 ITEKNQQIVAGK 390 + K Q I+ GK Sbjct: 62 V--KTQHILDGK 71 Score = 29.6 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 29/58 (50%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 ++ + ++VG + P V + FS G++ ++ D T S G+ +V ++ +A Sbjct: 84 QDKTGKIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADA 141 >5ZWM-4 nrPDB Length = 213 Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 52/176 (29%), Positives = 88/176 (50%), Gaps = 13/176 (7%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 +S ++YVG+++P +++ LY++F I V I+ +D + + GYA++ F + + Sbjct: 6 DSGNTVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQY 65 Query: 95 AIEQLNYTP-IKGRLCRI------MWSQRDPSLRKKGS----GNIFIKNLHPDIDNKALY 143 AI+ +N T + RL ++ + PS K +FIKNL ID+ L Sbjct: 66 AIKIMNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIKNLADSIDSDQLV 125 Query: 144 DTFSVFGDILSS-KIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYV 198 F+ FG ++ +I NGK K +V+FE+ A AI +LN L+ I V Sbjct: 126 KIFNKFGKLIREPEIFYLSNGKLKC-AYVYFEDFEKADLAIKSLNNQLVANNRITV 180 Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 52/179 (29%), Positives = 83/179 (46%), Gaps = 8/179 (4%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 +YV NI+ T EQ ELF + P++ KD +G+ F+ + DA A++ + Sbjct: 11 VYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIKIM 70 Query: 280 NDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLE 339 N++ ++L R + L + +AK LF+KNL DS+D ++L Sbjct: 71 NNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAK-----LFIKNLADSIDSDQLV 125 Query: 340 EEFAPYG-TITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIA 397 + F +G I ++ NGK K +V F E+A AI N Q+VA + V A Sbjct: 126 KIFNKFGKLIREPEIFYLSNGKLKC-AYVYFEDFEKADLAIKSLNNQLVANNRITVDYA 183 >1P1T-A nrPDB Length = 104 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 34/88 (38%), Positives = 52/88 (59%), Gaps = 3/88 (3%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDAD-GKLKGFGFVNYEKHEDAVKAVEA 278 +++V NI E T+EQ +++F++ GP+VS L D + GK KG+GF Y+ E A+ A+ Sbjct: 10 SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 69 Query: 279 LNDSELNGEKLYVGRA--QKKNERMHVL 304 LN E +G L V A +K E + L Sbjct: 70 LNGREFSGRALRVDNAASEKNKEELKSL 97 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 40/80 (50%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 +V+ S S++VG++ +E L DIFS +G V S R+ D T GY + + D E Sbjct: 3 AVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQET 62 Query: 92 GRKAIEQLNYTPIKGRLCRI 111 A+ LN GR R+ Sbjct: 63 ALSAMRNLNGREFSGRALRV 82 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 117 DPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEE 175 D SLR ++F+ N+ + + L D FS G ++S ++ D E GK KG+GF +++ Sbjct: 5 DRSLR-----SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQD 59 Query: 176 EGAAKEAIDALNGMLLNGQEIYVAPHLSRKERD 208 + A A+ LNG +G+ + V S K ++ Sbjct: 60 QETALSAMRNLNGREFSGRALRVDNAASEKNKE 92 Score = 37.4 bits (85), Expect = 0.020, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAK-VMRTENGKSKGFGFVCFSTPEEATKAITE 381 ++FV N+ +E+L++ F+ G + S + V E GK KG+GF + E A A+ Sbjct: 10 SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 69 Query: 382 KNQQIVAGKPLYV 394 N + +G+ L V Sbjct: 70 LNGREFSGRALRV 82 >2DH7-A nrPDB Length = 105 Score = 58.5 bits (140), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Query: 24 AATGSESQSVENSSA-SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 ++GS Q + S+ ++VGDL P ++ + F+P G +S RV +D T S GY Sbjct: 1 GSSGSSGQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYG 60 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDP 118 +V+F + AI + + GR R W+ R P Sbjct: 61 FVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKP 96 Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMR-TENGKSKGFGFVCFSTPEEATKAITE 381 ++FV +L + E ++ FAP+G I+ A+V++ GKSKG+GFV F +A AI Sbjct: 17 HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH 76 Query: 382 KNQQIVAGKPLYVAIAQRK 400 Q + G+ + A RK Sbjct: 77 MGGQWLGGRQIRTNWATRK 95 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Query: 210 QLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEK 268 Q ++T H+ +++V +++ E T E + FA FG I A + KD A GK KG+GFV++ Sbjct: 8 QKKDTSNHF-HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYN 66 Query: 269 HEDAVKAVEALNDSELNGEKLYVGRAQKK 297 DA A+ + L G ++ A +K Sbjct: 67 KLDAENAIVHMGGQWLGGRQIRTNWATRK 95 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDA 185 ++F+ +L P+I + + F+ FG I +++ D GKSKG+GFV F + A+ AI Sbjct: 17 HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH 76 Query: 186 LNGMLLNGQEI 196 + G L G++I Sbjct: 77 MGGQWLGGRQI 87 >2DO0-A nrPDB Length = 114 Score = 58.5 bits (140), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 29/79 (36%), Positives = 48/79 (60%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAIT 380 G +FV NLD V +KL+E F+ G + A ++ ++GKS+G G V F EA +AI+ Sbjct: 15 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAIS 74 Query: 381 EKNQQIVAGKPLYVAIAQR 399 N Q++ +P++V + +R Sbjct: 75 MFNGQLLFDRPMHVKMDER 93 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 42/72 (58%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ NL + K L + FS+ G ++ + I D++GKS+G G V FE+ A +AI Sbjct: 17 TVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMF 76 Query: 187 NGMLLNGQEIYV 198 NG LL + ++V Sbjct: 77 NGQLLFDRPMHV 88 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 47/82 (57%), Gaps = 4/82 (4%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 + ++V N++ + ++ +E+F+ G +V A + +D DGK +G G V +E+ +AV+A+ Sbjct: 16 STVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISM 75 Query: 279 LNDSELNGEKLYVGRAQKKNER 300 N L ++V K +ER Sbjct: 76 FNGQLLFDRPMHV----KMDER 93 >2DH9-A nrPDB Length = 89 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 35/75 (46%), Positives = 44/75 (58%), Gaps = 1/75 (1%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAI 183 GS IF++NL D K L D F+ G +L + I ENGKSKG G V FE A+ A Sbjct: 4 GSSGIFVRNLPFDFTWKMLKDKFNECGHVLYADIKM-ENGKSKGCGVVKFESPEVAERAC 62 Query: 184 DALNGMLLNGQEIYV 198 +NGM L+G+EI V Sbjct: 63 RMMNGMKLSGREIDV 77 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKN 383 +FV+NL + L+++F G + A + + ENGKSKG G V F +PE A +A N Sbjct: 8 IFVRNLPFDFTWKMLKDKFNECGHVLYADI-KMENGKSKGCGVVKFESPEVAERACRMMN 66 Query: 384 QQIVAGKPLYVAI 396 ++G+ + V I Sbjct: 67 GMKLSGREIDVRI 79 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 + ++V+N+ + T + ++ F + G ++ A ++ + +GK KG G V +E E A +A Sbjct: 6 SGIFVRNLPFDFTWKMLKDKFNECGHVLYADIKME-NGKSKGCGVVKFESPEVAERACRM 64 Query: 279 LNDSELNGEKLYV 291 +N +L+G ++ V Sbjct: 65 MNGMKLSGREIDV 77 >5ZWN-V nrPDB Length = 523 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 73/361 (20%), Positives = 139/361 (38%), Gaps = 74/361 (20%) Query: 27 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAIT---------- 75 G+ + S+ + LY+GDL+P+ + + I++ +G + ++R+ + Sbjct: 43 GASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGP 102 Query: 76 KTSLGYAYVNF--NDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPS--------LRKKGS 125 K + GY +V+F + H A + + ++ W+ S ++ + Sbjct: 103 KNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNN 162 Query: 126 GNIFIKNLHPDIDNKALYDTF-SVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAI 183 +IF+ +L P++ L++ F + + +KI D+ G SKG+GFV F + A+ Sbjct: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 Query: 184 DALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFG 243 + G+ LNG+ I V P +++ S + ++L N+E D +F Sbjct: 223 SEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSL-----NNENVDSRFLS------ 271 Query: 244 PIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHV 303 KG F++ NG K+N Sbjct: 272 ---------------KGQSFLS-------------------NGNN---NMGFKRNHMSQF 294 Query: 304 LKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKG 363 + + L +F+ L V +++L F P+GTI K+ GK G Sbjct: 295 IYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI---PVGKCCG 351 Query: 364 F 364 F Sbjct: 352 F 352 Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAP-YGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAI 379 ++FV +L +V + +L E F Y + + AK++ + G SKG+GFV F+ +E A+ Sbjct: 163 CSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLAL 222 Query: 380 TEKNQQIVAGKPLYVA 395 +E + G+ + V Sbjct: 223 SEMQGVFLNGRAIKVG 238 >5EN1-A nrPDB Length = 184 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 23/178 (12%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAV 273 K + L++ ++ ETT+E + + ++G + + +D A + +GFGFV + + V Sbjct: 6 KEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAE-V 64 Query: 274 KAVEALNDSELNGEKLYVGRAQKKNER----MHVLKKQYEAYRLEKMAKYQGVNLFVKNL 329 A A ++G + RA + E HV K+ LFV + Sbjct: 65 DAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKK----------------LFVGGI 108 Query: 330 DDSVDDEKLEEEFAPYGTITSAKVMR-TENGKSKGFGFVCFSTPEEATKAITEKNQQI 386 + ++ L + F YG I + +++ ++GK +GFGFV F + K + +K I Sbjct: 109 KEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTI 166 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 46/172 (26%), Positives = 78/172 (45%), Gaps = 7/172 (4%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L++G L +E L + + G ++ V RD +K S G+ +V F+ A+ Sbjct: 12 LFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAAR 71 Query: 100 NYTPIKGRLCRIMWSQRDPSLRKKGSG----NIFIKNLHPDIDNKALYDTFSVFGDILSS 155 ++ I GR+ + K G+ +F+ + D + L D F +G I + Sbjct: 72 PHS-IDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTI 130 Query: 156 KIATD-ENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 +I TD ++GK +GFGFV F++ + I +NG V LSR+E Sbjct: 131 EIITDRQSGKKRGFGFVTFDDHDPV-DKIVLQKYHTINGHNAEVRKALSRQE 181 >1SXL-A nrPDB Length = 97 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 1/64 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNLYV N+ TD+Q +F K+G IV ++ +D G+ +G FV Y K E+A +A+ Sbjct: 14 TNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAIS 73 Query: 278 ALND 281 ALN+ Sbjct: 74 ALNN 77 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 28/80 (35%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 NL+V NL ++ D++L+ F YG+I ++R + G+ +G FV ++ EEA +AI+ Sbjct: 14 TNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAIS 73 Query: 381 EKNQQIVAG--KPLYVAIAQ 398 N I G +PL V +A+ Sbjct: 74 ALNNVIPEGGSQPLSVRLAE 93 Score = 42.7 bits (99), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 34/63 (53%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +LYV +L ++++ L IF GS+ + RD +T G A+V +N E ++AI Sbjct: 14 TNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAIS 73 Query: 98 QLN 100 LN Sbjct: 74 ALN 76 Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 N+++ NL I + L F +G I+ I D+ G+ +G FV + + A+EAI A Sbjct: 15 NLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISA 74 Query: 186 LNGMLLNG 193 LN ++ G Sbjct: 75 LNNVIPEG 82 >6GD1-A nrPDB Length = 206 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 31/82 (37%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN-GKSKGFGFVCFSTPEEATKA 378 G +F+ NL D+ L + F P+G +T+ KV+R N K KGFGFV + EEA A Sbjct: 122 MGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMA 181 Query: 379 ITEKNQQIVAGKPLYVAIAQRK 400 I N + K L V+ K Sbjct: 182 IASLNGYRLGDKILQVSFKTNK 203 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDEN-GKSKGFGFVHFEEEGAAKEAIDAL 186 IFI NL D D L+ F FG + + K+ D N K KGFGFV A AI +L Sbjct: 126 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 185 Query: 187 NGMLLNGQEIYVA 199 NG L + + V+ Sbjct: 186 NGYRLGDKILQVS 198 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 33/62 (53%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 +++ +L E L+ +F P G+V++++V RD T G+ +V ++E AI Sbjct: 125 CIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIAS 184 Query: 99 LN 100 LN Sbjct: 185 LN 186 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 208 DSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDAD-GKLKGFGFVNY 266 D+ L + + +++ N+ + + ++F FG + + + +D + K KGFGFV Sbjct: 114 DANLAGSAMGWC-IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTM 172 Query: 267 EKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 300 +E+A A+ +LN L + L V K+ + Sbjct: 173 TNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 206 >6D0Y-A nrPDB Length = 176 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 49/107 (45%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 DQ E + + S +LYVG+L +E +Y++FS G + I + D + KT+ Sbjct: 42 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTAC 101 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 G+ +V + A+ +N T + R+ R W R+ G G Sbjct: 102 GFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRG 148 Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 7/112 (6%) Query: 181 EAIDALNGMLLNG--QEIYVAPHLSRKER----DSQLEETKAHYTNLYVKNINSETTDEQ 234 EA D ++G LL + YV R + + + E+ LYV N++ TT+EQ Sbjct: 16 EAADPMSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQ 75 Query: 235 FQELFAKFGPIVSASLEKDADGKLK-GFGFVNYEKHEDAVKAVEALNDSELN 285 ELF+K G I + D K GF FV Y DA A+ +N + L+ Sbjct: 76 IYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLD 127 Score = 32.3 bits (72), Expect = 0.62, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSK-GFGFVHFEEEGAAKE 181 K S +++ NL + +Y+ FS GDI + D+ K+ GF FV + A+ Sbjct: 57 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAEN 116 Query: 182 AIDALNGMLLNGQEI 196 A+ +NG L+ + I Sbjct: 117 AMRYINGTRLDDRII 131 >3NNA-A nrPDB Length = 175 Score = 52.8 bits (125), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 39/160 (24%), Positives = 76/160 (47%), Gaps = 9/160 (5%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENG---KSKGFGFVHFEEEGAAKEAID 184 +F+ + K L + F +G + + D + +SKG FV F AA EA + Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 65 Query: 185 ALNGM-LLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFG 243 AL+ M +L G + + E+++ +E+ K L++ I+ + T+ + +F+ FG Sbjct: 66 ALHNMKVLPGMHHPIQMKPADSEKNNAVEDRK-----LFIGMISKKCTENDIRVMFSSFG 120 Query: 244 PIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSE 283 I + + DG +G FV + A A++A++ ++ Sbjct: 121 QIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQ 160 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 30/188 (15%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG---KLKGFGFVNYEKHEDAVKAVE 277 ++V + +++ +ELF ++G + ++ +D + KG FV + + A++A Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 65 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRL-----EKMAKYQGVNLFVKNLDDS 332 AL++ M VL + ++ EK + LF+ + Sbjct: 66 ALHN-------------------MKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKK 106 Query: 333 VDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQ-QIVAG-- 389 + + F+ +G I +++R +G S+G FV F+T A AI +Q Q + G Sbjct: 107 CTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCS 166 Query: 390 KPLYVAIA 397 P+ V A Sbjct: 167 SPMVVKFA 174 Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 43/155 (27%), Positives = 66/155 (42%), Gaps = 10/155 (6%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK--TSLGYAYVNFNDHEAGRKAIE 97 ++VG + + SE L ++F G+V I V RD S G +V F +A +A Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 65 Query: 98 QL-NYTPIKGRLCRIMWSQRDPSLRKKGSG----NIFIKNLHPDIDNKALYDTFSVFGDI 152 L N + G I Q P+ +K + +FI + + FS FG I Sbjct: 66 ALHNMKVLPGMHHPI---QMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQI 122 Query: 153 LSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 +I +G S+G FV F A+ AI A++ Sbjct: 123 EECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMH 157 Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENG---KSKGFGFVCFSTPEEATK 377 + +FV + + ++ L E F YG + V+R + +SKG FV F T + A + Sbjct: 3 AIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALE 62 Query: 378 A 378 A Sbjct: 63 A 63 >2MYF-A nrPDB Length = 89 Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 28/72 (38%), Positives = 43/72 (59%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ + ID K+LYD FS FGDI + ++ + K++GF FV + E AK A+ + Sbjct: 13 LFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYNM 72 Query: 187 NGMLLNGQEIYV 198 N LNG+ I+V Sbjct: 73 NNFELNGKRIHV 84 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 48/84 (57%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 S N++ L+VG ++ ++ E LYDIFS G + +I V + TK + G+A+V + + + Sbjct: 5 SDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDD 64 Query: 92 GRKAIEQLNYTPIKGRLCRIMWSQ 115 + A+ +N + G+ + +S+ Sbjct: 65 AKHALYNMNNFELNGKRIHVNYSK 88 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKL-KGFGFVNYEKHEDAVKAVEAL 279 L+V I+ ++ ++F+ FG I + + + K +GF FV Y + +DA A+ + Sbjct: 13 LFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYNM 72 Query: 280 NDSELNGEKLYVGRAQ 295 N+ ELNG++++V ++ Sbjct: 73 NNFELNGKRIHVNYSK 88 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 LFV +D+++D++ L + F+ +G I + +V + K++GF FV + ++A A+ Sbjct: 13 LFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYNM 72 Query: 383 NQQIVAGKPLYV 394 N + GK ++V Sbjct: 73 NNFELNGKRIHV 84 >6QX9-R nrPDB Length = 480 Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 +F +L + V+D+ L F+ + + AKV+R + GK+KG+GFV F P + +A+ E Sbjct: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 Query: 382 KNQQIVAGKPLYVAIAQRKD 401 N + V +P+ + + KD Sbjct: 442 MNGKYVGSRPIKLRKSMWKD 461 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Query: 208 DSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNY 266 D L E A ++ ++ +E D+ F++F + A + +D GK KG+GFV++ Sbjct: 370 DPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSF 429 Query: 267 EKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLK 305 + D V+A+ +N + + + ++ K+ + V++ Sbjct: 430 KDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVR 468 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 114 SQRDPSLRKKGSGN--IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGF 170 S DPSL + + + IF +L ++++ L FS F L +K+ D+ GK+KG+GF Sbjct: 367 SWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGF 426 Query: 171 VHFEEEGAAKEAIDALNGMLLNGQEI 196 V F++ A+ +NG + + I Sbjct: 427 VSFKDPSDYVRAMREMNGKYVGSRPI 452 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 7/83 (8%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 ++ GDL V++ L FS S +V RD T + GY +V+F D +A+ ++ Sbjct: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 Query: 100 N-----YTPIKGRLCRIMWSQRD 117 N PIK L + MW R+ Sbjct: 443 NGKYVGSRPIK--LRKSMWKDRN 463 >5EV3-A nrPDB Length = 201 Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 29/161 (18%) Query: 152 ILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQ- 210 +L+ +I D+N F F+ F +A+ A +G++ GQ + + R+ D Q Sbjct: 46 VLAVQINQDKN-----FAFLEFRSVDETTQAM-AFDGIIFQGQSLKI-----RRPHDYQP 94 Query: 211 ---LEETKAHYT-------------NLYVKNINSETTDEQFQELFAKFGPIVSASLEKD- 253 + E + Y L++ + + D+Q +EL FGP+ + +L KD Sbjct: 95 LPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDS 154 Query: 254 ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRA 294 A G KG+ F Y +A+ LN +L +KL V RA Sbjct: 155 ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRA 195 Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 38/74 (51%) Query: 27 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNF 86 G S V +S+ L++G L +++ + ++ + G + + + +D+ T S GYA+ + Sbjct: 108 GVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEY 167 Query: 87 NDHEAGRKAIEQLN 100 D +AI LN Sbjct: 168 VDINVTDQAIAGLN 181 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 38/189 (20%), Positives = 76/189 (40%), Gaps = 37/189 (19%) Query: 40 LYVGDLEPSVSEAHLYDIF-----------SPIGSVSSIRVCRD---------AITKTSL 79 LYVG++ ++E + D F +P V ++++ +D ++ +T+ Sbjct: 11 LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQ 70 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKG---------SGNIFI 130 A+ K +Y P+ G +PS+ G + +FI Sbjct: 71 AMAFDGIIFQGQSLKIRRPHDYQPLPGM-------SENPSVYVPGVVSTVVPDSAHKLFI 123 Query: 131 KNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGM 189 L +++ + + + FG + + + D G SKG+ F + + +AI LNGM Sbjct: 124 GGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGM 183 Query: 190 LLNGQEIYV 198 L +++ V Sbjct: 184 QLGDKKLLV 192 >2YWK-A nrPDB Length = 95 Score = 52.4 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 28/72 (38%), Positives = 39/72 (54%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKN 383 +FV NL+ V +E L E F G +T + + GK K FGFVCF PE + AI N Sbjct: 19 VFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIALLN 78 Query: 384 QQIVAGKPLYVA 395 + G+P+ V+ Sbjct: 79 GIRLYGRPINVS 90 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 26/79 (32%), Positives = 40/79 (50%) Query: 121 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 +++ +F+ NL + + LY+ F G + I D GK K FGFV F+ + Sbjct: 12 QEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVS 71 Query: 181 EAIDALNGMLLNGQEIYVA 199 AI LNG+ L G+ I V+ Sbjct: 72 YAIALLNGIRLYGRPINVS 90 Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 5/70 (7%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 ++V N+ + +E ELF + GP+ ++ KD +GK K FGFV + KH ++V AL Sbjct: 19 VFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCF-KHPESVSYAIAL- 76 Query: 281 DSELNGEKLY 290 LNG +LY Sbjct: 77 ---LNGIRLY 83 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 E + +++VG+LE V E LY++F G ++ + +C+D K + +V F E+ Sbjct: 13 EEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPK-SFGFVCFKHPESVS 71 Query: 94 KAIEQLNYTPIKGR 107 AI LN + GR Sbjct: 72 YAIALLNGIRLYGR 85 >4LMZ-A nrPDB Length = 180 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 45/155 (29%), Positives = 68/155 (43%), Gaps = 10/155 (6%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKT--SLGYAYVNFNDHEAGRKAIE 97 ++VG + S SE L ++F P G+V I V RD S G +V F +A +A Sbjct: 11 MFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 70 Query: 98 QL-NYTPIKGRLCRIMWSQRDPSLRKKGSG----NIFIKNLHPDIDNKALYDTFSVFGDI 152 L N + G I Q P+ +K + +FI + + + FS FG I Sbjct: 71 ALHNIKTLPGMHHPI---QMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQI 127 Query: 153 LSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 +I +G S+G FV F A+ AI A++ Sbjct: 128 EECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMH 162 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 47/184 (25%), Positives = 81/184 (44%), Gaps = 22/184 (11%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDAD---GKLKGFGFVNYEKHEDAVKAVE 277 ++V I ++++ +ELF +G + ++ +D + KG FV + + A++A Sbjct: 11 MFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 70 Query: 278 AL-NDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDE 336 AL N L G MH Q + EK + LF+ + ++ Sbjct: 71 ALHNIKTLPG--------------MH-HPIQMKPADSEKSNAVEDRKLFIGMVSKKCNEN 115 Query: 337 KLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQ-QIVAG--KPLY 393 + F+P+G I +++R +G S+G FV FST A AI +Q Q + G P+ Sbjct: 116 DIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIV 175 Query: 394 VAIA 397 V A Sbjct: 176 VKFA 179 Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 9/160 (5%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDEN---GKSKGFGFVHFEEEGAAKEAID 184 +F+ + K L + F +G + + D + +SKG FV F AA EA + Sbjct: 11 MFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 70 Query: 185 ALNGM-LLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFG 243 AL+ + L G + + E+ + +E+ K L++ ++ + + + +F+ FG Sbjct: 71 ALHNIKTLPGMHHPIQMKPADSEKSNAVEDRK-----LFIGMVSKKCNENDIRVMFSPFG 125 Query: 244 PIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSE 283 I + + DG +G FV + A A++A++ S+ Sbjct: 126 QIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQ 165 Score = 36.2 bits (82), Expect = 0.042, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 3/61 (4%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN---GKSKGFGFVCFSTPEEATK 377 + +FV + S +++L+E F PYG + V+R + +SKG FV F T + A + Sbjct: 8 AIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALE 67 Query: 378 A 378 A Sbjct: 68 A 68 >5OO6-B nrPDB Length = 158 Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 29/107 (27%), Positives = 49/107 (45%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 DQ E + + S +LYVG+L +E +Y++FS G + I + D + KT+ Sbjct: 24 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTAC 83 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 G+ +V + A+ +N T + R+ R W R+ G G Sbjct: 84 GFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRG 130 Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 26/66 (39%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLK-GFGFVNYEKHEDAVKAVEAL 279 LYV N++ TT+EQ ELF+K G I + D K GF FV Y DA A+ + Sbjct: 44 LYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYI 103 Query: 280 NDSELN 285 N + L+ Sbjct: 104 NGTRLD 109 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSK-GFGFVHFEEEGAAKE 181 K S +++ NL + +Y+ FS GDI + D+ K+ GF FV + A+ Sbjct: 39 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAEN 98 Query: 182 AIDALNGMLLNGQEI 196 A+ +NG L+ + I Sbjct: 99 AMRYINGTRLDDRII 113 >5ZWM-X nrPDB Length = 148 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Query: 17 IQDDQKQAATGSESQSVEN---SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDA 73 I D + Q+ S QS N +A +Y+G+L ++E + +FS G + + RD Sbjct: 7 INDKELQSGILSPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDE 66 Query: 74 ITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRI 111 T S G+AY+ + D + A++ LN I GR +I Sbjct: 67 NTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKI 104 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDAD-GKLKGFGFVNYEKHEDAVKAVEAL 279 +Y+ N+N E T+ +F+++G V L +D + G+ +GF ++ YE + AV+ L Sbjct: 33 IYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNL 92 Query: 280 NDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLE 314 N ++ G L + + +R L+K YEA + E Sbjct: 93 NGFKIGGRALKIDHTFYRPKRS--LQKYYEAVKEE 125 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDEN-GKSKGFGFVHFEEEGAAKE 181 K + I+I NL+ ++ + FS +G + ++ DEN G+S+GF ++ +E++ + Sbjct: 28 KDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTIL 87 Query: 182 AIDALNGMLLNGQEIYVAPHLSRKERDSQ 210 A+D LNG + G+ + + R +R Q Sbjct: 88 AVDNLNGFKIGGRALKIDHTFYRPKRSLQ 116 >2CQB-A nrPDB Length = 102 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 15 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 74 Query: 383 NQQIVAGKPLYVAIAQRKDVRRS 405 N+ + G+ + V +A+ ++ S Sbjct: 75 NESELFGRTIRVNLAKPMRIKES 97 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Query: 28 SESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFN 87 S S + + LYVG L V + L+ F P G ++ I++ D T+ G+A+V F Sbjct: 3 SGSSGMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFE 62 Query: 88 DHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 E AI+ +N + + GR R+ ++ +R K SG Sbjct: 63 LAEDAAAAIDNMNESELFGRTIRVNLAK---PMRIKESG 98 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D + K +GF FV +E EDA A++ + Sbjct: 15 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 74 Query: 280 NDSELNGEKLYVGRAQ 295 N+SEL G + V A+ Sbjct: 75 NESELFGRTIRVNLAK 90 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 15 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 74 Query: 187 NGMLLNGQEIYV 198 N L G+ I V Sbjct: 75 NESELFGRTIRV 86 >1X5O-A nrPDB Length = 114 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 3/80 (3%) Query: 315 KMAKYQ---GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFST 371 +MAK Q NL++ NL S+D+++LE P+G + S +++R +G S+G GF + Sbjct: 16 QMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMES 75 Query: 372 PEEATKAITEKNQQIVAGKP 391 E+ I N + + P Sbjct: 76 TEKCEAVIGHFNGKFIKTPP 95 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 35/74 (47%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 N++I NL +D + L + FG ++S++I D +G S+G GF E + I Sbjct: 27 NLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHF 86 Query: 187 NGMLLNGQEIYVAP 200 NG + AP Sbjct: 87 NGKFIKTPPGVSAP 100 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 16/62 (25%), Positives = 30/62 (48%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 TNLY+ N+ +++ + + FG ++S + +D+ G +G GF E E + Sbjct: 26 TNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGH 85 Query: 279 LN 280 N Sbjct: 86 FN 87 Score = 35.8 bits (81), Expect = 0.048, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 E +LY+ +L S+ E L ++ P G V S R+ RD+ + TS G + E Sbjct: 22 EQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCE 80 Query: 94 KAIEQLNYTPIK 105 I N IK Sbjct: 81 AVIGHFNGKFIK 92 >1OO0-B nrPDB Length = 110 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 204 RKERDSQLE---ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLK 259 R E D +LE + L+V +I+ E +++ QE F +G I + L D G K Sbjct: 9 RNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSK 68 Query: 260 GFGFVNYEKHEDAVKAVEALNDSELNGEKLYV 291 G+ V YE H+ A+ A EALN +E+ G+ + V Sbjct: 69 GYALVEYETHKQALAAKEALNGAEIMGQTIQV 100 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ ++H + + + F +G+I + + D G SKG+ V +E A A +AL Sbjct: 29 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 88 Query: 187 NGMLLNGQEIYV 198 NG + GQ I V Sbjct: 89 NGAEIMGQTIQV 100 Score = 37.0 bits (84), Expect = 0.026, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 33/75 (44%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + E + + F G + +I + D T S GYA V + H+ A E L Sbjct: 29 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 88 Query: 100 NYTPIKGRLCRIMWS 114 N I G+ ++ W Sbjct: 89 NGAEIMGQTIQVDWC 103 Score = 35.0 bits (79), Expect = 0.097, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV ++ + +++++E+F YG I + + + G SKG+ V + T ++A A Sbjct: 25 EGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAA 84 Query: 379 ITEKNQQIVAGKPLYV 394 N + G+ + V Sbjct: 85 KEALNGAEIMGQTIQV 100 >1D8Z-A nrPDB Length = 89 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++F+ LF G I S L +D G+ G+GFVNY DA KA+ Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 278 ALNDSELNGEKLYVGRAQ 295 LN +L + + V A+ Sbjct: 65 TLNGLKLQTKTIKVSYAR 82 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 45/81 (55%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 +S +L V L ++++ +F IG + S ++ RD IT SLGY +VN++D K Sbjct: 2 DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADK 61 Query: 95 AIEQLNYTPIKGRLCRIMWSQ 115 AI LN ++ + ++ +++ Sbjct: 62 AINTLNGLKLQTKTIKVSYAR 82 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 N+ + L ++ F GDI S K+ D+ G+S G+GFV++ + A +AI+ Sbjct: 6 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 65 Query: 186 LNGMLLNGQEIYVA 199 LNG+ L + I V+ Sbjct: 66 LNGLKLQTKTIKVS 79 Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 NL V L ++ ++ + F G I S K++R + G+S G+GFV +S P +A KAI Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 381 EKNQQIVAGKPLYVAIAQ 398 N + K + V+ A+ Sbjct: 65 TLNGLKLQTKTIKVSYAR 82 >2KU7-A nrPDB Length = 140 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 1/75 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 383 NQQIVAGKPLYVAIA 397 N+ + G+ + V +A Sbjct: 126 NESELFGRTIRVNLA 140 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 187 NGMLLNGQEIYV 198 N L G+ I V Sbjct: 126 NESELFGRTIRV 137 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D + K +GF FV +E EDA A++ + Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 280 NDSELNGEKLYVGRA 294 N+SEL G + V A Sbjct: 126 NESELFGRTIRVNLA 140 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 24/72 (33%), Positives = 38/72 (52%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 LYVG L V + L+ F P G ++ I++ D T+ G+A+V F E AI+ + Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 100 NYTPIKGRLCRI 111 N + + GR R+ Sbjct: 126 NESELFGRTIRV 137 >5SZW-A nrPDB Length = 101 Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Query: 201 HLSRKERDSQLEETKAHY--TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGK 257 H+S D E+ + TNL V + T ++ + LF+ G + SA L +D G Sbjct: 2 HMSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGH 61 Query: 258 LKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQ 295 G+GFVNY +DA +A+ LN L + + V A+ Sbjct: 62 SLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYAR 99 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 43/78 (55%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 22 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 81 Query: 98 QLNYTPIKGRLCRIMWSQ 115 LN ++ + ++ +++ Sbjct: 82 TLNGLRLQSKTIKVSYAR 99 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 G N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ A Sbjct: 20 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 79 Query: 183 IDALNGMLLNGQEIYVA 199 I+ LNG+ L + I V+ Sbjct: 80 INTLNGLRLQSKTIKVS 96 >5MQF-o nrPDB Length = 301 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 383 NQQIVAGKPLYVAIAQ 398 N+ + G+ + V +A+ Sbjct: 68 NESELFGRTIRVNLAK 83 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D + K +GF FV +E EDA A++ + Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 280 NDSELNGEKLYVGRAQ 295 N+SEL G + V A+ Sbjct: 68 NESELFGRTIRVNLAK 83 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 LYVG L V + L+ F P G ++ I++ D T+ G+A+V F E AI+ + Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 100 NYTPIKGRLCRIMWSQRDPSLRKKGS 125 N + + GR R+ ++ P K+GS Sbjct: 68 NESELFGRTIRVNLAK--PMRIKEGS 91 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 187 NGMLLNGQEIYV 198 N L G+ I V Sbjct: 68 NESELFGRTIRV 79 >1RK8-A nrPDB Length = 165 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V +I+ E +++ QE F +G I + L D G KG+ V YE H+ A+ A EAL Sbjct: 75 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 134 Query: 280 NDSELNGEKLYV 291 N +E+ G+ + V Sbjct: 135 NGAEIMGQTIQV 146 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 33/75 (44%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + E + + F G + +I + D T S GYA V + H+ A E L Sbjct: 75 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 134 Query: 100 NYTPIKGRLCRIMWS 114 N I G+ ++ W Sbjct: 135 NGAEIMGQTIQVDWC 149 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV ++ + +++++E+F YG I + + + G SKG+ V + T ++A A Sbjct: 71 EGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAA 130 Query: 379 ITEKNQQIVAGKPLYV 394 N + G+ + V Sbjct: 131 KEALNGAEIMGQTIQV 146 >3MDF-A nrPDB Length = 85 Score = 48.5 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 383 NQQIVAGKPLYVAIAQ 398 N+ + G+ + V +A+ Sbjct: 70 NESELFGRTIRVNLAK 85 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D + K +GF FV +E EDA A++ + Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 280 NDSELNGEKLYVGRAQ 295 N+SEL G + V A+ Sbjct: 70 NESELFGRTIRVNLAK 85 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 187 NGMLLNGQEIYV 198 N L G+ I V Sbjct: 70 NESELFGRTIRV 81 Score = 45.4 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 25/80 (31%), Positives = 41/80 (51%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 S+ + LYVG L V + L+ F P G ++ I++ D T+ G+A+V F E Sbjct: 2 SMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAED 61 Query: 92 GRKAIEQLNYTPIKGRLCRI 111 AI+ +N + + GR R+ Sbjct: 62 AAAAIDNMNESELFGRTIRV 81 >2J0Q-D nrPDB Length = 109 Score = 48.5 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V ++ E T+E + FA++G I + L D G LKG+ V YE +++A A+E L Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 280 NDSELNGEKLYV 291 N +L G+ + V Sbjct: 70 NGQDLMGQPISV 81 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 187 NGMLLNGQEIYV 198 NG L GQ I V Sbjct: 70 NGQDLMGQPISV 81 Score = 38.1 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV + + +E + ++FA YG I + + + G KG+ V + T +EA A Sbjct: 6 EGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAA 65 Query: 379 ITEKNQQIVAGKPLYV 394 + N Q + G+P+ V Sbjct: 66 MEGLNGQDLMGQPISV 81 Score = 33.1 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 70 NGQDLMGQPISVDW 83 >1D9A-A nrPDB Length = 85 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 N+++ L + K + FS +G I++S+I D+ G S+G GF+ F++ A+EAI Sbjct: 3 NLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKG 62 Query: 186 LNG 188 LNG Sbjct: 63 LNG 65 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 40/62 (64%), Gaps = 1/62 (1%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEA 278 NLYV + + ++ ++LF+++G I+++ + D A G +G GF+ ++K +A +A++ Sbjct: 3 NLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKG 62 Query: 279 LN 280 LN Sbjct: 63 LN 64 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 NL+V L ++ +++E+ F+ YG I +++++ + G S+G GF+ F EA +AI Sbjct: 3 NLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKG 62 Query: 382 KNQQ--IVAGKPLYVAIA 397 N Q + A +P+ V A Sbjct: 63 LNGQKPLGAAEPITVKFA 80 Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 33/63 (52%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 A+LYV L ++S+ + +FS G + + R+ D T S G ++ F+ +AI+ Sbjct: 2 ANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIK 61 Query: 98 QLN 100 LN Sbjct: 62 GLN 64 >2ERR-A nrPDB Length = 109 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 213 ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDA 272 E K+ L+V NI D +++F +FG I+ + + G KGFGFV +E DA Sbjct: 24 ENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGS-KGFGFVTFENSADA 82 Query: 273 VKAVEALNDSELNGEKLYVGRAQKK 297 +A E L+ + + G K+ V A + Sbjct: 83 DRAREKLHGTVVEGRKIEVNNATAR 107 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 25/57 (43%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Query: 142 LYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYV 198 L F FG IL +I +E G SKGFGFV FE A A + L+G ++ G++I V Sbjct: 46 LRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRAREKLHGTVVEGRKIEV 101 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 K Q L V N+ D L + F +G I +++ E G SKGFGFV F +A + Sbjct: 26 KSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADR 84 Query: 378 AITEKNQQIVAGKPLYV 394 A + + +V G+ + V Sbjct: 85 AREKLHGTVVEGRKIEV 101 >2HYI-B nrPDB Length = 91 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V ++ E T+E + FA++G I + L D G LKG+ V YE +++A A+E L Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 280 NDSELNGEKLYV 291 N +L G+ + V Sbjct: 72 NGQDLMGQPISV 83 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 187 NGMLLNGQEIYV 198 NG L GQ I V Sbjct: 72 NGQDLMGQPISV 83 Score = 37.7 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV + + +E + ++FA YG I + + + G KG+ V + T +EA A Sbjct: 8 EGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAA 67 Query: 379 ITEKNQQIVAGKPLYV 394 + N Q + G+P+ V Sbjct: 68 MEGLNGQDLMGQPISV 83 Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 72 NGQDLMGQPISVDW 85 >1P27-B nrPDB Length = 106 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V ++ E T+E + FA++G I + L D G LKG+ V YE +++A A+E L Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 280 NDSELNGEKLYV 291 N +L G+ + V Sbjct: 86 NGQDLMGQPISV 97 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 187 NGMLLNGQEIYV 198 NG L GQ I V Sbjct: 86 NGQDLMGQPISV 97 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV + + +E + ++FA YG I + + + G KG+ V + T +EA A Sbjct: 22 EGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAA 81 Query: 379 ITEKNQQIVAGKPLYV 394 + N Q + G+P+ V Sbjct: 82 MEGLNGQDLMGQPISV 97 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 18/75 (24%), Positives = 35/75 (46%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 100 NYTPIKGRLCRIMWS 114 N + G+ + W Sbjct: 86 NGQDLMGQPISVDWC 100 >6ASO-A nrPDB Length = 424 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 51/186 (27%), Positives = 87/186 (46%), Gaps = 18/186 (9%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 + +L++ + PS ++ ++ D+ I V+ SIR+ TS +AY++ E R Sbjct: 89 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 147 Query: 95 AIEQLN------YTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPD-IDNKALYDTFS 147 +E+LN YT + + S+R S +G I I+NL + +D L ++F Sbjct: 148 CVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGR-EIMIRNLSTELLDENLLRESFE 206 Query: 148 VFGDILSSKI--ATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA-----P 200 FG I I E+ + F+ FE + +A+ A+ +N LL +EI V+ P Sbjct: 207 GFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKKP 265 Query: 201 HLSRKE 206 L R E Sbjct: 266 FLERNE 271 >3HI9-A nrPDB Length = 84 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++ + LF+ G + SA L +D G G+GFVNY +DA +A+ Sbjct: 5 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 64 Query: 278 ALNDSELNGEKLYVGRAQ 295 LN L + + V A+ Sbjct: 65 TLNGLRLQSKTIKVSYAR 82 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 43/78 (55%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 5 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 64 Query: 98 QLNYTPIKGRLCRIMWSQ 115 LN ++ + ++ +++ Sbjct: 65 TLNGLRLQSKTIKVSYAR 82 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 G N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ A Sbjct: 3 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 62 Query: 183 IDALNGMLLNGQEIYVA 199 I+ LNG+ L + I V+ Sbjct: 63 INTLNGLRLQSKTIKVS 79 >2SXL-A nrPDB Length = 88 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 46/80 (57%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 S+ +L V L +++ LY +F IG +++ R+ RD T S GYA+V+F ++A Sbjct: 2 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRA 61 Query: 96 IEQLNYTPIKGRLCRIMWSQ 115 I+ LN ++ + ++ +++ Sbjct: 62 IKVLNGITVRNKRLKVSYAR 81 Score = 42.7 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVK 274 A TNL V + + TD + LF GPI + + +D G G+ FV++ D+ + Sbjct: 1 ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQR 60 Query: 275 AVEALNDSELNGEKLYVGRAQKKNERM 301 A++ LN + ++L V A+ E + Sbjct: 61 AIKVLNGITVRNKRLKVSYARPGGESI 87 >4ZKA-A nrPDB Length = 100 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 213 ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDA 272 E K+ L+V NI D +++F +FG I+ + + G KGFGFV +E DA Sbjct: 3 ENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGS-KGFGFVTFENSADA 61 Query: 273 VKAVEALNDSELNGEKLYVGRAQKK 297 +A E L+ + + G K+ V A + Sbjct: 62 DRAREKLHGTVVEGRKIEVNNATAR 86 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 142 LYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPH 201 L F FG IL +I +E G SKGFGFV FE A A + L+G ++ G++I V Sbjct: 25 LRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNA 83 Query: 202 LSR 204 +R Sbjct: 84 TAR 86 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 K Q L V N+ D L + F +G I +++ E G SKGFGFV F +A + Sbjct: 5 KSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADR 63 Query: 378 AITEKNQQIVAGKPLYV 394 A + + +V G+ + V Sbjct: 64 AREKLHGTVVEGRKIEV 80 >3EX7-B nrPDB Length = 126 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V ++ E T+E + FA++G I + L D G LKG+ V YE +++A A+E L Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 280 NDSELNGEKLYV 291 N +L G+ + V Sbjct: 85 NGQDLMGQPISV 96 Score = 39.3 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 187 NGMLLNGQEIYV 198 NG L GQ I V Sbjct: 85 NGQDLMGQPISV 96 Score = 37.0 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV + + +E + ++FA YG I + + + G KG+ V + T +EA A Sbjct: 21 EGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAA 80 Query: 379 ITEKNQQIVAGKPLYV 394 + N Q + G+P+ V Sbjct: 81 MEGLNGQDLMGQPISV 96 Score = 32.3 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 85 NGQDLMGQPISVDW 98 >1H6K-X nrPDB Length = 98 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 DQ E + + S +LYVG+L +E +Y++FS G + I + D + KT+ Sbjct: 1 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKM-KTAC 59 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMW 113 G+ +V + A+ +N T + R+ R W Sbjct: 60 GFCFVEYYSRADAENAMRYINGTRLDDRIIRTDW 93 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 25/65 (38%), Positives = 34/65 (52%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 LYV N++ TT+EQ ELF+K G I + D GF FV Y DA A+ +N Sbjct: 21 LYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFVEYYSRADAENAMRYIN 80 Query: 281 DSELN 285 + L+ Sbjct: 81 GTRLD 85 Score = 33.5 bits (75), Expect = 0.28, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 36/74 (48%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 K S +++ NL + +Y+ FS GDI + D+ + GF FV + A+ A Sbjct: 16 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFVEYYSRADAENA 75 Query: 183 IDALNGMLLNGQEI 196 + +NG L+ + I Sbjct: 76 MRYINGTRLDDRII 89 >4FXV-A nrPDB Length = 99 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++ + LF+ G + SA L +D G G+GFVNY +DA +A+ Sbjct: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79 Query: 278 ALNDSELNGEKLYVGRAQ 295 LN L + + V A+ Sbjct: 80 TLNGLRLQSKTIKVSYAR 97 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Query: 319 YQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATK 377 +QG NL V L ++ ++L F+ G + SAK++R + G S G+GFV + T ++A + Sbjct: 17 FQGTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76 Query: 378 AITEKNQQIVAGKPLYVAIAQ 398 AI N + K + V+ A+ Sbjct: 77 AINTLNGLRLQSKTIKVSYAR 97 Score = 45.1 bits (105), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 43/78 (55%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79 Query: 98 QLNYTPIKGRLCRIMWSQ 115 LN ++ + ++ +++ Sbjct: 80 TLNGLRLQSKTIKVSYAR 97 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 1/74 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ AI+ Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80 Query: 186 LNGMLLNGQEIYVA 199 LNG+ L + I V+ Sbjct: 81 LNGLRLQSKTIKVS 94 >6FF4-1 nrPDB Length = 322 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 52/91 (57%), Gaps = 4/91 (4%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKE 181 K S IF+ L ++ + FS +G+I++ + D+ GKSKGF F+ +E++ + Sbjct: 33 KDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTIL 92 Query: 182 AIDALNGMLLNGQEIYVAPHLS--RKERDSQ 210 A+D NG+ + G+ I V H+S R +DS+ Sbjct: 93 AVDNFNGIKIKGRTIRV-DHVSNYRAPKDSE 122 Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 342 FAPYGTITSAKVMR-TENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYV 394 F+ YG I + ++R + GKSKGF F+C+ A+ N + G+ + V Sbjct: 56 FSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRV 109 >5YZG-w nrPDB Length = 174 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V ++ E T+E + FA++G I + L D G LKG+ V YE +++A A+E L Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 280 NDSELNGEKLYV 291 N +L G+ + V Sbjct: 135 NGQDLMGQPISV 146 Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 187 NGMLLNGQEIYV 198 NG L GQ I V Sbjct: 135 NGQDLMGQPISV 146 Score = 37.0 bits (84), Expect = 0.024, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKA 378 +G LFV + + +E + ++FA YG I + + + G KG+ V + T +EA A Sbjct: 71 EGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAA 130 Query: 379 ITEKNQQIVAGKPLYV 394 + N Q + G+P+ V Sbjct: 131 MEGLNGQDLMGQPISV 146 Score = 32.3 bits (72), Expect = 0.58, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 135 NGQDLMGQPISVDW 148 >1JH4-A nrPDB Length = 98 Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Query: 489 GFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES 548 G P A+ Q+Q+Q LGE+L+ + A + AGKITGM+L++ E+ +LES Sbjct: 4 GSPLTASMLASAPPQEQKQMLGERLFPLIQAM--HPTLAGKITGMLLEIDNSELLHMLES 61 Query: 549 DELFEQHYKEASAAYESFKKEQEQQ 573 E EA A ++ + ++ Q Sbjct: 62 PESLRSKVDEAVAVLQAHQAKEAAQ 86 >2CQ3-A nrPDB Length = 103 Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 L+V NI D +++F +FG I+ + + G KGFGFV +E DA +A E L+ Sbjct: 18 LHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGS-KGFGFVTFENSADADRAREKLH 76 Query: 281 DSELNGEKLYVGRAQKK 297 + + G K+ V A + Sbjct: 77 GTVVEGRKIEVNNATAR 93 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 23/103 (22%) Query: 102 TPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE 161 TP + + I + RDP LR+ F FG IL +I +E Sbjct: 14 TPKRLHVSNIPFRFRDPDLRQ----------------------MFGQFGKILDVEIIFNE 51 Query: 162 NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSR 204 G SKGFGFV FE A A + L+G ++ G++I V +R Sbjct: 52 RG-SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATAR 93 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKN 383 L V N+ D L + F +G I +++ E G SKGFGFV F +A +A + + Sbjct: 18 LHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRAREKLH 76 Query: 384 QQIVAGKPLYV 394 +V G+ + V Sbjct: 77 GTVVEGRKIEV 87 >5ZWN-Q nrPDB Length = 300 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 ++++G L + E L F G + IR+ +D IT+ S GYA++ F D + + A ++ Sbjct: 108 TIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKE 167 Query: 99 LNY---TPIKGRLC 109 + IK R+C Sbjct: 168 IGVHRGIQIKDRIC 181 Score = 35.4 bits (80), Expect = 0.070, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAI 183 IFI L D+D L F FG+I +I D+ KSKG+ F+ F++ ++K A Sbjct: 109 IFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAF 165 >6G90-B nrPDB Length = 300 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 ++++G L + E L F G + IR+ +D IT+ S GYA++ F D + + A ++ Sbjct: 108 TIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKE 167 Query: 99 LNY---TPIKGRLC 109 + IK R+C Sbjct: 168 IGVHRGIQIKDRIC 181 Score = 35.4 bits (80), Expect = 0.071, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAI 183 IFI L D+D L F FG+I +I D+ KSKG+ F+ F++ ++K A Sbjct: 109 IFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAF 165 >2XS2-A nrPDB Length = 102 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 2/78 (2%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEK 382 +FV +D +D+ ++ FA YG++ K++ G SKG+GFV F + K + + Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIV--E 68 Query: 383 NQQIVAGKPLYVAIAQRK 400 +Q GK L + A RK Sbjct: 69 SQINFHGKKLKLGPAIRK 86 Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Query: 211 LEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHE 270 L E K ++V I+ + + + FA++G + + D G KG+GFV++ Sbjct: 2 LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDV 61 Query: 271 DAVKAVEALNDSELNGEKLYVGRAQKK 297 D K VE+ +G+KL +G A +K Sbjct: 62 DVQKIVES--QINFHGKKLKLGPAIRK 86 Score = 37.4 bits (85), Expect = 0.018, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 43/80 (53%), Gaps = 4/80 (5%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDA- 185 +F+ + +D + F+ +G + KI TD G SKG+GFV F + ++ +++ Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQ 70 Query: 186 LNGMLLNGQEIYVAPHLSRK 205 +N +G+++ + P + ++ Sbjct: 71 IN---FHGKKLKLGPAIRKQ 87 Score = 34.7 bits (78), Expect = 0.12, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 10/86 (11%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNF-NDHEAGRKAIE 97 +++VG ++ + E + F+ GSV +++ D T S GY +V+F ND + + Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIVES 69 Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKK 123 Q+N+ K +L P++RK+ Sbjct: 70 QINFHGKKLKL--------GPAIRKQ 87 >1G9L-A nrPDB Length = 144 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Query: 487 QGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLL 546 QG P A+ Q+Q+Q LGE+L+ + A + AGKITGM+L++ E+ +L Sbjct: 48 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAM--HPTLAGKITGMLLEIDNSELLHML 105 Query: 547 ESDELFEQHYKEASAAYESFKKEQEQQ 573 ES E EA A ++ + ++ Q Sbjct: 106 ESPESLRSKVDEAVAVLQAHQAKEAAQ 132 >2XS5-A nrPDB Length = 87 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 2/78 (2%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEK 382 +FV +D +D+ ++ FA YG++ K++ G SKG+GFV F + K + + Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIV--E 68 Query: 383 NQQIVAGKPLYVAIAQRK 400 +Q GK L + A RK Sbjct: 69 SQINFHGKKLKLGPAIRK 86 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Query: 211 LEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHE 270 L E K ++V I+ + + + FA++G + + D G KG+GFV++ Sbjct: 2 LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDV 61 Query: 271 DAVKAVEALNDSELNGEKLYVGRAQKK 297 D K VE+ +G+KL +G A +K Sbjct: 62 DVQKIVES--QINFHGKKLKLGPAIRK 86 Score = 37.4 bits (85), Expect = 0.016, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 43/80 (53%), Gaps = 4/80 (5%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDA- 185 +F+ + +D + F+ +G + KI TD G SKG+GFV F + ++ +++ Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQ 70 Query: 186 LNGMLLNGQEIYVAPHLSRK 205 +N +G+++ + P + ++ Sbjct: 71 IN---FHGKKLKLGPAIRKQ 87 Score = 35.4 bits (80), Expect = 0.069, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 10/86 (11%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNF-NDHEAGRKAIE 97 +++VG ++ + E + F+ GSV +++ D T S GY +V+F ND + + Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIVES 69 Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKK 123 Q+N+ K +L P++RK+ Sbjct: 70 QINFHGKKLKL--------GPAIRKQ 87 >2CPD-A nrPDB Length = 99 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%) Query: 212 EETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHED 271 E+T + LYV+N+ T++E ++ F P ++E+ K++ + FV++ ED Sbjct: 9 EDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKP---GAVERVK--KIRDYAFVHFSNRED 63 Query: 272 AVKAVEALNDSELNGEKLYVGRAQ 295 AV+A++ALN L+G + V A+ Sbjct: 64 AVEAMKALNGKVLDGSPIEVTLAK 87 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 5/78 (6%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKN 383 L+V+NL S +E +E+EF I V R + K + + FV FS E+A +A+ N Sbjct: 18 LYVRNLMLSTSEEMIEKEF---NNIKPGAVERVK--KIRDYAFVHFSNREDAVEAMKALN 72 Query: 384 QQIVAGKPLYVAIAQRKD 401 +++ G P+ V +A+ D Sbjct: 73 GKVLDGSPIEVTLAKPVD 90 Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 21/36 (58%) Query: 164 KSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA 199 K + + FVHF A EA+ ALNG +L+G I V Sbjct: 49 KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 84 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 10/78 (12%) Query: 40 LYVGDLEPSVSEAHLYDIFSPI--GSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 LYV +L S SE + F+ I G+V ++ RD YA+V+F++ E +A++ Sbjct: 18 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD--------YAFVHFSNREDAVEAMK 69 Query: 98 QLNYTPIKGRLCRIMWSQ 115 LN + G + ++ Sbjct: 70 ALNGKVLDGSPIEVTLAK 87 >2X04-A nrPDB Length = 80 Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Query: 503 QKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEASAA 562 Q+Q+Q LGE+L+ + A + AGKITGM+L++ E+ +LES E EA A Sbjct: 17 QEQKQMLGERLFPLIQAM--HPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAV 74 Query: 563 YESFK 567 ++ + Sbjct: 75 LQAHQ 79 >6C8U-1 nrPDB Length = 115 Score = 42.0 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 36/72 (50%) Query: 27 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNF 86 G+E+ ++++ +++G L S L D FS G + V RD TK S G+ +V F Sbjct: 14 GTENLYFQSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 73 Query: 87 NDHEAGRKAIEQ 98 D + K + Q Sbjct: 74 ADPASVDKVLGQ 85 Score = 37.4 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 5/88 (5%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK-SKGFGFVCFSTPEEATKAITEK 382 +F+ L + L + F+ +G I VMR K S+GFGFV F+ P K + + Sbjct: 27 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 86 Query: 383 NQQI----VAGKPLYVAIAQRKDVRRSQ 406 + ++ + K + AQ K V R++ Sbjct: 87 HHELDSKTIDPKVAFPRRAQPKMVTRTK 114 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 122 KKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGK-SKGFGFVHFEEEGAAK 180 + +G +FI L +L D FS FG+I + D K S+GFGFV F + + Sbjct: 21 QSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVD 80 Query: 181 EAI 183 + + Sbjct: 81 KVL 83 Score = 29.6 bits (65), Expect = 4.3, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKL-KGFGFVNY 266 +++ ++ +T+ + ++ F+KFG I + +D K +GFGFV + Sbjct: 27 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 73 >1NMR-A nrPDB Length = 85 Score = 41.6 bits (96), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 2/57 (3%) Query: 503 QKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEA 559 ++Q+ LGE+LY + A N AA K+TGM+L++ E+ LL++ L + +EA Sbjct: 21 EQQKNVLGERLYNHIVAI--NPAAAAKVTGMLLEMDNGEILNLLDTPGLLDAKVQEA 75 >4WKR-A nrPDB Length = 208 Score = 41.6 bits (96), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Query: 191 LNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASL 250 L G I L + +D E+ + Y L KN+N + +F K G +V S+ Sbjct: 104 LEGTRIRRKKPLGERPKD---EDERTVYVELLPKNVNHS----WIERVFGKCGNVVYISI 156 Query: 251 EK-DADGKLKGFGFVNYEKHEDAVKAVEALND 281 + G KGF FV +E E A KA+E LN+ Sbjct: 157 PHYKSTGDPKGFAFVEFETKEQAAKAIEFLNN 188 Score = 35.0 bits (79), Expect = 0.083, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 32/65 (49%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 ++YV L +V+ + + +F G+V I + T G+A+V F E KAIE Sbjct: 126 TVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEF 185 Query: 99 LNYTP 103 LN P Sbjct: 186 LNNPP 190 Score = 32.0 bits (71), Expect = 0.80, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN-GKSKGFGFVCFSTPEEATKAI 379 ++V+ L +V+ +E F G + + ++ G KGF FV F T E+A KAI Sbjct: 126 TVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAI 183 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIAT-DENGKSKGFGFVHFEEEGAAKEAIDA 185 ++++ L ++++ + F G+++ I G KGF FV FE + A +AI+ Sbjct: 126 TVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEF 185 Query: 186 LN 187 LN Sbjct: 186 LN 187 >3CW1-K nrPDB Length = 216 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASL-EKDADGKLKGFGFVNYEKHEDAVKAV 276 + L+V +N +TT+ + + F +GPI + GK +G+ F+ YE D A Sbjct: 102 FKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAY 161 Query: 277 EALNDSELNGEKLYV 291 + + +++G ++ V Sbjct: 162 KHADGKKIDGRRVLV 176 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 112 MWS-QRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS-SKIATDENGKSKGFG 169 MW DP+ + +F+ ++ D L F V+G I + + +GK +G+ Sbjct: 88 MWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYA 147 Query: 170 FVHFEEEGAAKEAIDALNGMLLNGQEIYV 198 F+ +E E A +G ++G+ + V Sbjct: 148 FIEYEHERDMHSAYKHADGKKIDGRRVLV 176 Score = 33.1 bits (74), Expect = 0.39, Method: Compositional matrix adjust. Identities = 18/82 (21%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 LFV ++ + KL EF YG I ++ ++ +GK +G+ F+ + + A Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 382 KNQQIVAGKPLYVAIAQRKDVR 403 + + + G+ + V + + + V+ Sbjct: 164 ADGKKIDGRRVLVDVERGRTVK 185 >2MGZ-B nrPDB Length = 105 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENG-KSKGFGFVHFEEEGAAKEAIDAL 186 IF+ L +K L++ F FGDI + + TD N KS+G+GFV ++ +A+ A Sbjct: 19 IFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDP 78 Query: 187 NGML 190 N ++ Sbjct: 79 NPII 82 Score = 35.4 bits (80), Expect = 0.070, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENG-KSKGFGFVCFSTPEEATKAITEK 382 +FV L D+ L E F +G I A V+ N KS+G+GFV A +A + Sbjct: 19 IFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDP 78 Query: 383 NQQIVAGKPLYVAIA 397 N I+ G+ V +A Sbjct: 79 N-PIIDGRKANVNLA 92 Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAV 276 +T ++V + T+D+ E F +FG I A + D + K +G+GFV + A +A Sbjct: 16 FTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERAC 75 Query: 277 EALN 280 + N Sbjct: 76 KDPN 79 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 28/61 (45%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 ++VG L S+ L++ F G + V D T+ S GY +V D + +A + Sbjct: 19 IFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDP 78 Query: 100 N 100 N Sbjct: 79 N 79 >5X3Y-A nrPDB Length = 96 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVK 274 +H ++V ++ TT E + F +FG + A L D + +GFGFV +E ED V+ Sbjct: 2 SHMKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES-EDIVE 60 Query: 275 AVEALNDSELNGEKLYVGRAQKK 297 V ++ E+N + + +AQ K Sbjct: 61 KVCEIHFHEINNKMVECKKAQPK 83 >6QX9-1K nrPDB Length = 437 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASL-EKDADGKLKGFGFVNYEKHEDAVKAV 276 + L+V +N +TT+ + + F +GPI + GK +G+ F+ YE D A Sbjct: 102 FKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAY 161 Query: 277 EALNDSELNGEKLYV 291 + + +++G ++ V Sbjct: 162 KHADGKKIDGRRVLV 176 Score = 37.0 bits (84), Expect = 0.024, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 112 MWS-QRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS-SKIATDENGKSKGFG 169 MW DP+ + +F+ ++ D L F V+G I + + +GK +G+ Sbjct: 88 MWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYA 147 Query: 170 FVHFEEEGAAKEAIDALNGMLLNGQEIYV 198 F+ +E E A +G ++G+ + V Sbjct: 148 FIEYEHERDMHSAYKHADGKKIDGRRVLV 176 Score = 32.7 bits (73), Expect = 0.48, Method: Compositional matrix adjust. Identities = 18/81 (22%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEK 382 LFV ++ + KL EF YG I ++ ++ +GK +G+ F+ + + A Sbjct: 105 LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA 164 Query: 383 NQQIVAGKPLYVAIAQRKDVR 403 + + + G+ + V + + + V+ Sbjct: 165 DGKKIDGRRVLVDVERGRTVK 185 >6H7A-A nrPDB Length = 92 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Query: 491 PRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDE 550 P + Q+QR ALG++L+ KV E A KITGM L++ P+E + LL + Sbjct: 16 PITPQELESMSPQEQRAALGDRLFLKVYEIAP--ELAPKITGMFLEMKPKEAYELLNDQK 73 Query: 551 LFEQHYKEASAAYES 565 E+ EA ++ Sbjct: 74 RLEERVTEALCVLKA 88 >2LEC-A nrPDB Length = 135 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGK-LKGFGFVNYEKHEDAVKAVE 277 T+L V N+ T+ + + +F K+G + + +D K +GF FV + DA A++ Sbjct: 48 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 107 Query: 278 ALNDSELNGEKLYVGRAQ 295 A++ + L+G +L V A+ Sbjct: 108 AMDGAVLDGRELRVQMAR 125 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 38/77 (49%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 SL V +L S L +F G V + + RD TK S G+A+V F+D A++ Sbjct: 49 SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDA 108 Query: 99 LNYTPIKGRLCRIMWSQ 115 ++ + GR R+ ++ Sbjct: 109 MDGAVLDGRELRVQMAR 125 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGK-SKGFGFVHFEEEGAAKE 181 +G ++ + NL L F +G + I D K S+GF FV F ++ A++ Sbjct: 45 EGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAED 104 Query: 182 AIDALNGMLLNGQEIYV 198 A+DA++G +L+G+E+ V Sbjct: 105 AMDAMDGAVLDGRELRV 121 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK-SKGFGFVCFSTPEEATKAITE 381 +L V NL + L F YG + + R K S+GF FV F +A A+ Sbjct: 49 SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDA 108 Query: 382 KNQQIVAGKPLYVAIAQ 398 + ++ G+ L V +A+ Sbjct: 109 MDGAVLDGRELRVQMAR 125 >4PKD-B nrPDB Length = 279 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASL-EKDADGKLKGFGFVNYEKHEDAVKAV 276 + L+V +N +TT+ + + F +GPI + GK +G+ F+ YE D A Sbjct: 166 FKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAY 225 Query: 277 EALNDSELNGEKLYV 291 + + +++G ++ V Sbjct: 226 KHADGKKIDGRRVLV 240 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 112 MWS-QRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS-SKIATDENGKSKGFG 169 MW DP+ + +F+ ++ D L F V+G I + + +GK +G+ Sbjct: 152 MWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYA 211 Query: 170 FVHFEEEGAAKEAIDALNGMLLNGQEIYV 198 F+ +E E A +G ++G+ + V Sbjct: 212 FIEYEHERDMHSAYKHADGKKIDGRRVLV 240 Score = 36.2 bits (82), Expect = 0.045, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Query: 127 NIFIKNLHPDIDN----KALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 I+I NL+ I K+LY FS FG IL I + K +G FV F+E +A A Sbjct: 10 TIYINNLNEKIKKDELKKSLYAIFSQFGQILD--ILVSRSLKMRGQAFVIFKEVSSATNA 67 Query: 183 IDALNGM 189 + ++ G Sbjct: 68 LRSMQGF 74 Score = 32.7 bits (73), Expect = 0.50, Method: Compositional matrix adjust. Identities = 18/82 (21%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 LFV ++ + KL EF YG I ++ ++ +GK +G+ F+ + + A Sbjct: 168 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 227 Query: 382 KNQQIVAGKPLYVAIAQRKDVR 403 + + + G+ + V + + + V+ Sbjct: 228 ADGKKIDGRRVLVDVERGRTVK 249 >2KN4-A nrPDB Length = 158 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGK-LKGFGFVNYEKHEDAVKAVE 277 T+L V N+ T+ + + +F K+G + + +D K +GF FV + DA A++ Sbjct: 71 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 130 Query: 278 ALNDSELNGEKLYVGRAQ 295 A++ + L+G +L V A+ Sbjct: 131 AMDGAVLDGRELRVQMAR 148 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 38/77 (49%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 SL V +L S L +F G V + + RD TK S G+A+V F+D A++ Sbjct: 72 SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDA 131 Query: 99 LNYTPIKGRLCRIMWSQ 115 ++ + GR R+ ++ Sbjct: 132 MDGAVLDGRELRVQMAR 148 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGK-SKGFGFVHFEEEGAAKE 181 +G ++ + NL L F +G + I D K S+GF FV F ++ A++ Sbjct: 68 EGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAED 127 Query: 182 AIDALNGMLLNGQEIYV 198 A+DA++G +L+G+E+ V Sbjct: 128 AMDAMDGAVLDGRELRV 144 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK-SKGFGFVCFSTPEEATKAITE 381 +L V NL + L F YG + + R K S+GF FV F +A A+ Sbjct: 72 SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDA 131 Query: 382 KNQQIVAGKPLYVAIAQ 398 + ++ G+ L V +A+ Sbjct: 132 MDGAVLDGRELRVQMAR 148 >2CPE-A nrPDB Length = 113 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 11/87 (12%) Query: 221 LYVKNINSETTDEQFQELFAKFG----------PIVSASLEKDADGKLKGFGFVNYEKHE 270 +YV+ +N T + + F + G P++ L+K+ GK KG V+YE Sbjct: 18 IYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET-GKPKGDATVSYEDPP 76 Query: 271 DAVKAVEALNDSELNGEKLYVGRAQKK 297 A AVE + + G KL V A+KK Sbjct: 77 TAKAAVEWFDGKDFQGSKLKVSLARKK 103 Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust. Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 9/106 (8%) Query: 24 AATGSESQSVENS-SASLYVGDLEPSVSEAHLYDIFSPIGSVS--------SIRVCRDAI 74 ++GS E+S ++++YV L SV+ L D F G V I + D Sbjct: 1 GSSGSSGDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE 60 Query: 75 TKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 120 T G A V++ D + A+E + +G ++ +++ P + Sbjct: 61 TGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 106 >2DH8-A nrPDB Length = 105 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTP 372 LFV LD S E L F+ YG + +M+ + +S+GFGFV F P Sbjct: 19 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDP 68 Score = 32.3 bits (72), Expect = 0.54, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDEN-GKSKGFGFVHFEE 175 G +F+ L + L FS +G+++ I D+ +S+GFGFV F++ Sbjct: 17 GKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKD 67 >6FYY-r nrPDB Length = 274 Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Query: 322 VNLFVKNLDDSVDDEKLEEEFA-PYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKAI 379 L + ++++ D+ L EE P+ I V+R E GKS+G FV FS+ E A +A+ Sbjct: 191 CTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQAL 250 Score = 32.3 bits (72), Expect = 0.51, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 46 EPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIK 105 E S+ E L+ F+PI VS V R+ T S G A+V F+ E +A+ L+ Sbjct: 204 ENSLREELLFP-FAPIPRVS---VVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYM 259 Query: 106 GRLCRIMWSQ 115 + R+ WS+ Sbjct: 260 NLILRVEWSK 269 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 155 SKIATDENGKSKGFGFVHFEEEGAAKEAIDALNG 188 S + E GKS+G FV F E A++A+ L+G Sbjct: 222 SVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDG 255 >2DGS-A nrPDB Length = 99 Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 2/81 (2%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAVEAL 279 ++V I + + +E F KFG + + DA+ + +GFGF+ +E + +AV + Sbjct: 13 IFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN-M 71 Query: 280 NDSELNGEKLYVGRAQKKNER 300 + ++ G+K+ V RA+ ++ + Sbjct: 72 HFHDIMGKKVEVKRAEPRDSK 92 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSA-KVMRTENGKSKGFGFVCFSTPEEATKAITEK 382 +FV + + + +L E F +G +T + E + +GFGF+ F + +A+ Sbjct: 13 IFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMH 72 Query: 383 NQQIVAGKPLYVAIAQRKDVRRS 405 I+ GK + V A+ +D + S Sbjct: 73 FHDIM-GKKVEVKRAEPRDSKSS 94 Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAID 184 IF+ + + L + F FG + + D E + +GFGF+ FE+E + +A++ Sbjct: 13 IFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN 70 >2RS2-A nrPDB Length = 109 Score = 37.7 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 30/64 (46%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 +S +++G L ++ L + F G V V RD +TK S G+ +V F D K Sbjct: 23 SSGCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDK 82 Query: 95 AIEQ 98 + Q Sbjct: 83 VLAQ 86 Score = 35.0 bits (79), Expect = 0.093, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAI 379 G +F+ L E L E F +G + VMR +S+GFGFV F K + Sbjct: 25 GCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL 84 Query: 380 TEKNQQI 386 + ++ Sbjct: 85 AQSRHEL 91 Score = 30.8 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 7/83 (8%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKL-KGFGFVNYEKHEDAVKAVEAL 279 +++ ++ +TT E +E F +FG + + +D K +GFGFV + + V V A Sbjct: 28 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF-MDQAGVDKVLAQ 86 Query: 280 NDSELNGEKL-----YVGRAQKK 297 + EL+ + + + RAQ K Sbjct: 87 SRHELDSKTIDPKVAFPRRAQPK 109 >5YVG-X nrPDB Length = 528 Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 9/81 (11%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSK--------IATD-ENGKSKGFGFVHFEEEGA 178 IF++ L ++ +++ D F G I ++K + TD E GK KG V F++ + Sbjct: 289 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 348 Query: 179 AKEAIDALNGMLLNGQEIYVA 199 AK AID +G +G I V+ Sbjct: 349 AKAAIDWFDGKEFSGNPIKVS 369 Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 9/86 (10%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKSKGFGFVCFSTPEE 374 +FV+ L ++V E + + F G I + K E GK KG V F P Sbjct: 289 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 348 Query: 375 ATKAITEKNQQIVAGKPLYVAIAQRK 400 A AI + + +G P+ V+ A R+ Sbjct: 349 AKAAIDWFDGKEFSGNPIKVSFATRR 374 >6QX9-1A nrPDB Length = 282 Score = 37.4 bits (85), Expect = 0.019, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Query: 127 NIFIKNLHPDIDN----KALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 I+I NL+ I K+LY FS FG IL I + K +G FV F+E +A A Sbjct: 11 TIYINNLNEKIKKDELKKSLYAIFSQFGQILD--ILVSRSLKMRGQAFVIFKEVSSATNA 68 Query: 183 IDALNG 188 + ++ G Sbjct: 69 LRSMQG 74 >2DYD-A nrPDB Length = 85 Score = 37.0 bits (84), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%) Query: 503 QKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEASAA 562 + QR LGE LY V ++ A K+TGM+L++ EV LLES + + EA Sbjct: 20 ETQRMMLGENLYPLVDQLEHDQ--AAKVTGMLLEMDQTEVLHLLESPDALKAKVAEAMEV 77 Query: 563 YESFKK 568 S ++ Sbjct: 78 LRSAQQ 83 >1UAW-A nrPDB Length = 77 Score = 36.6 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 28/59 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 +++G L ++ L + F G V V RD +TK S G+ +V F D K + Q Sbjct: 3 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 61 Score = 33.5 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEK 382 +F+ L E L E F +G + VMR +S+GFGFV F K + + Sbjct: 3 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 62 Query: 383 NQQI 386 ++ Sbjct: 63 RHEL 66 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKL-KGFGFVNYEKHEDAVKAVEAL 279 +++ ++ +TT E +E F +FG + + +D K +GFGFV + + V V A Sbjct: 3 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF-MDQAGVDKVLAQ 61 Query: 280 NDSELNGEKL 289 + EL+ + + Sbjct: 62 SRHELDSKTI 71 >5OSG-h nrPDB Length = 235 Score = 36.2 bits (82), Expect = 0.035, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 12/118 (10%) Query: 124 GSGN-IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 GS N +++KN A + FS G ++ ++ + + + V FE A K+A Sbjct: 52 GSSNGVYVKNWGTGSVADAT-NVFSAAGKVVKVQL------RRQRYALVFFENSAAVKKA 104 Query: 183 IDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 240 ID N + GQ + V P + + D+ + + ++ TT Q ELFA Sbjct: 105 IDLFNEKEVLGQTVLVVPAKASPKPDAHENSSCVFVSPIF----RPSTTKAQVMELFA 158 >1I2T-A nrPDB Length = 61 Score = 36.2 bits (82), Expect = 0.046, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 2/55 (3%) Query: 505 QRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEA 559 RQALGE+LY +V A A KITGM+L+L P ++ LL S++ EA Sbjct: 1 HRQALGERLYPRVQAM--QPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEA 53 >2MKI-A nrPDB Length = 203 Score = 35.8 bits (81), Expect = 0.053, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGDIL---SSKIATDENGKSKGFGFVHFEEEGAAKE 181 S +F+ L PDID + +F FG ++ K + KG+ F+ F++E + + Sbjct: 12 SRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQA 71 Query: 182 AIDAL 186 IDA Sbjct: 72 LIDAC 76 >2MST-A nrPDB Length = 75 Score = 35.8 bits (81), Expect = 0.058, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 ++V ++ TT E + F +FG + A L D + +GFGFV +E ED V+ V + Sbjct: 2 IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES-EDIVEKVCEI 60 Query: 280 NDSELNGEKLYVGRA 294 + E+N + + +A Sbjct: 61 HFHEINNKMVECKKA 75 >5OPT-h nrPDB Length = 257 Score = 35.8 bits (81), Expect = 0.059, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 52/125 (41%), Gaps = 11/125 (8%) Query: 168 FGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNIN 227 + + FE A K+AID NG G + V P + + D + + ++ Sbjct: 111 YAIIFFENAAAVKKAIDLFNGKEFMGNVLSVVPAKTTPKPDPHANSSVVFVSPIF----R 166 Query: 228 SETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGE 287 + TT +Q ELF+ + + + + +V + A +AV+ N +E G+ Sbjct: 167 ASTTKKQILELFSGMKVLRLRTYRNN-------YAYVYLDTPAAAQRAVKEKNGAEFRGK 219 Query: 288 KLYVG 292 +L V Sbjct: 220 QLRVA 224 Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%) Query: 352 KVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQR---KDVRRSQLA 408 KV+R ++ + +V TP A +A+ EKN GK L VA++ R KD R++ A Sbjct: 182 KVLRLRTYRN-NYAYVYLDTPAAAQRAVKEKNGAEFRGKQLRVALSTRSLAKDRARAERA 240 Query: 409 QQIQA 413 + + A Sbjct: 241 RLLMA 245 >2MKK-A nrPDB Length = 213 Score = 35.4 bits (80), Expect = 0.077, Method: Compositional matrix adjust. Identities = 40/196 (20%), Positives = 73/196 (37%), Gaps = 31/196 (15%) Query: 111 IMWSQRDPSLRKKG---SGNIFIKNLHPDIDNKALYDTFSVFGDI---LSSKIATDENGK 164 + WS + P K S +F+ + DI L +TF VFG + K Sbjct: 1 MTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCP 60 Query: 165 SKGFGFVHFEEEGAAKEAIDA-----------------LNGMLLNGQEIYVAPHLSR--- 204 KG+ ++ FE E + + + A ++ + +E+ V P + Sbjct: 61 PKGYVYLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSN 120 Query: 205 --KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFG 262 + +L+ ++ + +N+E +L FG +V A ++ D G G Sbjct: 121 FVRSPSQRLDPSRTVFVGALHGMLNAEALAAILNDL---FGGVVYAGIDTDKHKYPIGSG 177 Query: 263 FVNYEKHEDAVKAVEA 278 V + +KAV A Sbjct: 178 RVTFNNQRSYLKAVSA 193 >3N9U-C nrPDB Length = 156 Score = 35.0 bits (79), Expect = 0.078, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASL---EKDADGKLKGFGFVNYEKHEDAVKAVE 277 +YV + + TTD+Q ++ G L E A+G+ KG+ V K +E Sbjct: 58 VYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLE 117 Query: 278 ALNDSELNGEKLYVGRAQKKN 298 L LNGEK+ V A ++N Sbjct: 118 LLPGKVLNGEKVDVRPATRQN 138 Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 151 DILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAP 200 D++ K A + NG+SKG+ V E + + ++ L G +LNG+++ V P Sbjct: 83 DVVELKFAENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRP 133 >2RUG-A nrPDB Length = 114 Score = 35.0 bits (79), Expect = 0.080, Method: Composition-based stats. Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 3/61 (4%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDIL---SSKIATDENGKSKGFGFVHFEEEGAAKEAID 184 +F+ L PDID + +F FG ++ K + KG+ F+ F+EE + + ID Sbjct: 11 VFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALID 70 Query: 185 A 185 A Sbjct: 71 A 71 >1X4A-A nrPDB Length = 109 Score = 35.0 bits (79), Expect = 0.084, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 I++ NL PDI K + D F +G I + G F FV FE+ A++A+ + Sbjct: 25 IYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPP--FAFVEFEDPRDAEDAVYGRD 82 Query: 188 GMLLNGQEIYV 198 G +G + V Sbjct: 83 GYDYDGYRLRV 93 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 +YV N+ + + +++F K+G I L+ G F FV +E DA AV + Sbjct: 25 IYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGG--PPFAFVEFEDPRDAEDAVYGRD 82 Query: 281 DSELNGEKLYV 291 + +G +L V Sbjct: 83 GYDYDGYRLRV 93 Score = 28.9 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 9/65 (13%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLG---YAYVNFNDHEA 91 N+ +YVG+L P + + D+F G++ RD K G +A+V F D Sbjct: 20 NNDCRIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRD 73 Query: 92 GRKAI 96 A+ Sbjct: 74 AEDAV 78 >6EM1-o nrPDB Length = 220 Score = 35.0 bits (79), Expect = 0.095, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 316 MAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEE 374 + +Y G+ ++V L +++L + FA +G + ++ R + G S+ +GF+ F E+ Sbjct: 86 LEEYSGI-IYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKED 144 Query: 375 ATKAITEKNQQIVAGKPLYVAI 396 A A N ++ G L V + Sbjct: 145 AMIAQESMNNYLLMGHLLQVRV 166 Score = 34.7 bits (78), Expect = 0.12, Method: Compositional matrix adjust. Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 8/130 (6%) Query: 206 ERDSQLEETKAHYTNL-YVKNINSETTDEQFQELFAKFGPIVSASLEKDAD-GKLKGFGF 263 E+ S+ ++T Y+ + YV + +++ + FA+FG + L ++ G + +GF Sbjct: 77 EKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGF 136 Query: 264 VNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVN 323 + + EDA+ A E++N+ L G L V R K ++ L K + +EK G+ Sbjct: 137 LEFVNKEDAMIAQESMNNYLLMGHLLQV-RVLPKGAKIEKLYKYKKRVLVEK-----GIT 190 Query: 324 LFVKNLDDSV 333 VK L D++ Sbjct: 191 KPVKQLKDNM 200 >2I2Y-A nrPDB Length = 150 Score = 35.0 bits (79), Expect = 0.095, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 +YV N+ + + + F +GP+ S + ++ GF FV +E DA AV L+ Sbjct: 76 VYVGNLGNNGNKTELERAFGYYGPLRSVWVARNP----PGFAFVEFEDPRDAADAVRELD 131 Query: 281 DSELNGEKLYV 291 L G ++ V Sbjct: 132 GRTLCGCRVRV 142 Score = 30.4 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 +++ NL + + L F +G + S +A + GF FV FE+ A +A+ L+ Sbjct: 76 VYVGNLGNNGNKTELERAFGYYGPLRSVWVARN----PPGFAFVEFEDPRDAADAVRELD 131 Query: 188 GMLLNGQEIYVAPHLSRKER 207 G L G + V LS E+ Sbjct: 132 GRTLCGCRVRV--ELSNGEK 149 >2F9J-A nrPDB Length = 125 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 13/99 (13%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 L ++N+ + T E+ ++F K+GPI + + +G +V YE DA A + L+ Sbjct: 21 LMIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPET--RGTAYVVYEDIFDAKNACDHLS 78 Query: 281 DSELNGEKLYV-----GRA------QKKNERMHVLKKQY 308 + L V RA +KK E++ +LK++Y Sbjct: 79 GFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY 117 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 10/99 (10%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 + I+NL I + +YD F +G I +I +++G +V +E+ AK A D L+ Sbjct: 21 LMIRNLPYKITAEEMYDIFGKYGPI--RQIRVGNTPETRGTAYVVYEDIFDAKNACDHLS 78 Query: 188 GMLLNGQEIYVAPH--------LSRKERDSQLEETKAHY 218 G + + + V + + K+++ QL+ K Y Sbjct: 79 GFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY 117 Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 23 QAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 QAA + + + L + +L ++ +YDIF G + IRV T + G A Sbjct: 4 QAAKRANIRLPPEVNRILMIRNLPYKITAEEMYDIFGKYGPIRQIRV---GNTPETRGTA 60 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRK 122 YV + D + A + L+ + R +++ + + +K Sbjct: 61 YVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQK 100 >1JMT-A nrPDB Length = 104 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 229 ETTDEQFQELFA----KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSEL 284 E DE F+E+F K+G + ++ + L G +V + + EDA KAV LN+ Sbjct: 34 EHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWF 93 Query: 285 NGEKLY 290 NG+ ++ Sbjct: 94 NGQPIH 99 >2LCW-A nrPDB Length = 116 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 9/88 (10%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSK--------IATD-ENGKSKGFGFVHFEEEGA 178 IF++ L ++ +++ D F G I ++K + TD E GK KG V F++ + Sbjct: 10 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 69 Query: 179 AKEAIDALNGMLLNGQEIYVAPHLSRKE 206 AK AID +G +G I V+ R + Sbjct: 70 AKAAIDWFDGKEFSGNPIKVSFATRRAD 97 Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 9/86 (10%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKSKGFGFVCFSTPEE 374 +FV+ L ++V E + + F G I + K E GK KG V F P Sbjct: 10 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 69 Query: 375 ATKAITEKNQQIVAGKPLYVAIAQRK 400 A AI + + +G P+ V+ A R+ Sbjct: 70 AKAAIDWFDGKEFSGNPIKVSFATRR 95 >2LA6-A nrPDB Length = 99 Score = 33.5 bits (75), Expect = 0.27, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 9/81 (11%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSK--------IATD-ENGKSKGFGFVHFEEEGA 178 IF++ L ++ +++ D F G I ++K + TD E GK KG V F++ + Sbjct: 16 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 75 Query: 179 AKEAIDALNGMLLNGQEIYVA 199 AK AID +G +G I V+ Sbjct: 76 AKAAIDWFDGKEFSGNPIKVS 96 Score = 29.6 bits (65), Expect = 4.2, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKSKGFGFVCFSTPEE 374 +FV+ L ++V E + + F G I + K E GK KG V F P Sbjct: 16 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 75 Query: 375 ATKAITEKNQQIVAGKPLYVAIA 397 A AI + + +G P+ V+ A Sbjct: 76 AKAAIDWFDGKEFSGNPIKVSFA 98 >3Q2T-C nrPDB Length = 229 Score = 33.5 bits (75), Expect = 0.28, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Query: 128 IFIKNLHPDIDNKALYDTFSVFG--DILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 ++I NL ++ L + G DIL K + NG+SKGF V E ++K+ +D Sbjct: 71 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 130 Query: 185 ALNGMLLNGQEIYVAP 200 L L+GQ V P Sbjct: 131 LLPKRELHGQNPVVTP 146 Score = 32.3 bits (72), Expect = 0.51, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFG--PIVSASL-EKDADGKLKGFGFVNYEKHEDAVKAVE 277 LY+ N+ TTDE E G I+ E A+G+ KGF V + K ++ Sbjct: 71 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 130 Query: 278 ALNDSELNGEKLYVGRAQKK 297 L EL+G+ V K+ Sbjct: 131 LLPKRELHGQNPVVTPVNKQ 150 >2DGQ-A nrPDB Length = 108 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 L+V I ++ + LF +FG I ++ KD G KG F+ Y + A+KA AL Sbjct: 18 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 77 Query: 280 ND 281 ++ Sbjct: 78 HE 79 >2RT3-A nrPDB Length = 97 Score = 33.1 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 5/59 (8%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITE 381 N+F+ NL + + ++++ E+ P+G I K++ N FV F A KA+ E Sbjct: 20 NVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERN-----IAFVHFLNIAAAIKAVQE 73 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 16/95 (16%) Query: 24 AATGSESQSVENSSA--SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGY 81 A+ S +V+ S A ++++G+L ++E + + P G + I++ T Sbjct: 3 ASNSSVLLAVQQSGACRNVFLGNLPNGITEDEIREDLEPFGPIDQIKIV------TERNI 56 Query: 82 AYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQR 116 A+V+F + A KA+++L P WS+R Sbjct: 57 AFVHFLNIAAAIKAVQELPLNP--------KWSKR 83 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 N+F+ NL I + + FG I KI T+ N FVHF AA +A+ L Sbjct: 20 NVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERN-----IAFVHFLNIAAAIKAVQEL 74 >3P6Y-C nrPDB Length = 90 Score = 32.7 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 151 DILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAP 200 DIL K + NG+SKGF V E ++K+ +D L L+GQ V P Sbjct: 29 DILEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTP 79 Score = 32.0 bits (71), Expect = 0.85, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 3/79 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFGP---IVSASLEKDADGKLKGFGFVNYEKHEDAVKAVE 277 LY+ N+ TTDE E G + E A+G+ KGF V + K ++ Sbjct: 4 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 63 Query: 278 ALNDSELNGEKLYVGRAQK 296 L EL+G+ V + K Sbjct: 64 LLPKRELHGQNPVVTPSNK 82 >2I14-A nrPDB Length = 395 Score = 32.7 bits (73), Expect = 0.50, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 16/94 (17%) Query: 266 YEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLE-KMAKYQGVNL 324 Y++ +AV A EAL G+KL+ R + R +K E R E K+ Y V + Sbjct: 218 YDEKVEAVMAAEAL------GKKLFAVRLDTPSSRRGNFRKIIEEVRWELKVRGYDWVKI 271 Query: 325 FVKNLDDSVDDEKLEE------EFAPYGTITSAK 352 FV +D+EK++E F G I SAK Sbjct: 272 FVSG---GLDEEKIKEIVDVVDAFGVGGAIASAK 302 >6FYY-p nrPDB Length = 763 Score = 32.0 bits (71), Expect = 0.75, Method: Compositional matrix adjust. Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 140 KALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLN 192 KAL FS G +++ + DE GK+KGF FV AK+ I + +G L+ Sbjct: 97 KALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLD 150 >3NS5-A nrPDB Length = 91 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 140 KALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLN 192 KAL FS G +++ + DE GK+KGF FV AK+ I + +G L+ Sbjct: 27 KALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLD 80 >5K1H-B nrPDB Length = 576 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 141 ALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIY 197 ++ FS FG I ++ +E+GK+KG+ F+ + A +A+ +G L+ Q + Sbjct: 37 VIHKIFSKFGKI-TNDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTF 92 Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 236 QELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLY 290 ++F+KFG I + + DGK KG+ F+ Y AV AV+ + +L+ + + Sbjct: 39 HKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTF 92 >3NNH-A nrPDB Length = 88 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN---GKSKGFGFVCFSTPEEATK 377 + +FV + + ++ L E F YG + V+R + +SKG FV F T + A + Sbjct: 3 AIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALE 62 Query: 378 A 378 A Sbjct: 63 A 63 Score = 28.5 bits (62), Expect = 9.0, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 2/63 (3%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKT--SLGYAYVNFNDHEAGRKAIE 97 ++VG + + SE L ++F G+V I V RD S G +V F +A +A Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 65 Query: 98 QLN 100 L+ Sbjct: 66 ALH 68 >2KVI-A nrPDB Length = 96 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 9/61 (14%) Query: 38 ASLYVGDLE-PSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 + L++G+L +VS+ L+ IFSP G + I + K + G ++ F++ ++ R AI Sbjct: 11 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI------KNAFG--FIQFDNPQSVRDAI 62 Query: 97 E 97 E Sbjct: 63 E 63 >2XNQ-A nrPDB Length = 97 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 36/61 (59%), Gaps = 9/61 (14%) Query: 38 ASLYVGDLE-PSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 + L++G+L +VS+ L+ IFSP G + I + ++A + ++ F++ ++ R AI Sbjct: 23 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-KNA-------FGFIQFDNPQSVRDAI 74 Query: 97 E 97 E Sbjct: 75 E 75 >2CQH-A nrPDB Length = 93 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 8/82 (9%) Query: 221 LYVKNINSETTDEQFQELFA-KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEAL 279 LY+ N++ T + ++LF + P+ L K G+ FV+Y A++A+E L Sbjct: 11 LYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLK------SGYAFVDYPDQNWAIRAIETL 64 Query: 280 NDS-ELNGEKLYVGRAQKKNER 300 + EL+G+ + V + K R Sbjct: 65 SGKVELHGKIMEVDYSVSKKLR 86 Score = 28.9 bits (63), Expect = 6.0, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 6/61 (9%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 LY+G+L P+V+ L +F + + + K+ GYA+V++ D +AIE L Sbjct: 11 LYIGNLSPAVTADDLRQLFGD----RKLPLAGQVLLKS--GYAFVDYPDQNWAIRAIETL 64 Query: 100 N 100 + Sbjct: 65 S 65 >2KRB-A nrPDB Length = 81 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 141 ALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIY 197 ++ FS FG I ++ +E+GK+KG+ F+ + A +A+ +G L+ Q + Sbjct: 23 VIHKIFSKFGKI-TNDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTF 78 Score = 29.3 bits (64), Expect = 4.6, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 236 QELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLY 290 ++F+KFG I + + DGK KG+ F+ Y AV AV+ + +L+ + + Sbjct: 25 HKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTF 78 >2M2B-A nrPDB Length = 131 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 3/69 (4%) Query: 27 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP--IGSVSSIRVCRDAITKTSLGYAYV 84 GSE S EN++ ++ + +L P + + +P + S S++RV +D T+ + G+A++ Sbjct: 14 GSEPSS-ENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFI 72 Query: 85 NFNDHEAGR 93 + EA + Sbjct: 73 QLSTIEAAQ 81 >1WP5-A nrPDB Length = 323 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 34/104 (32%), Positives = 48/104 (46%), Gaps = 17/104 (16%) Query: 238 LFAKFGPIVSASLEKDADGKLKGFG-----FVNYEKHEDAVKAVEALNDSELNGEKLYVG 292 LF G + + + D + K G + ++ E+ +KA+ +ND ELNG L+V Sbjct: 55 LFTNKGNYLYCPVHELPDIRWKDLGQHIANIIPIDRDEEIIKAI-PINDFELNGYFLFVT 113 Query: 293 R--AQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVD 334 R KK E H Y+A R K G+NL KN D VD Sbjct: 114 RNGMVKKTELKH-----YKAQRYSK--PLTGINL--KNDDQVVD 148 >4QU7-A nrPDB Length = 81 Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Query: 236 QELFAKFGPI--VSASLEKDADGKLKGFGFVNYEKHEDAVKAV 276 Q++ F P+ V ++E + GK G V++E HEDAV A+ Sbjct: 16 QDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAM 58 >2NLW-A nrPDB Length = 105 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 141 ALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIY 197 ++ FS FG I ++ +E+GK+KG+ F+ + A +A+ +G L+ Q + Sbjct: 37 VIHKIFSKFGKI-TNDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTF 92 Score = 29.3 bits (64), Expect = 5.4, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 236 QELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLY 290 ++F+KFG I + + DGK KG+ F+ Y AV AV+ + +L+ + + Sbjct: 39 HKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTF 92 >6ID0-O nrPDB Length = 420 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Query: 303 VLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSK 362 +LK+ RL+ L+V L D++ + L F +G I + V++ + Sbjct: 213 LLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ---- 268 Query: 363 GFGFVCFSTPEEATKAITEK--NQQIVAGKPLYVAIAQRKDVR 403 F+ F+T +A + EK N+ IV G+ L V + + R Sbjct: 269 -CAFIQFAT-RQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAAR 309 >2MMY-A nrPDB Length = 97 Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 9/88 (10%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSK--------IATDEN-GKSKGFGFVHFEEEGA 178 IF++ L + + + F G I ++K + TD++ GK KG V F++ + Sbjct: 10 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 69 Query: 179 AKEAIDALNGMLLNGQEIYVAPHLSRKE 206 AK AID +G +G I V+ R E Sbjct: 70 AKAAIDWFDGKEFHGNIIKVSFATRRPE 97 >5ZJN-A nrPDB Length = 253 Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust. Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 28 SESQSVE--NSSASLYVGDLEPSVSEAHLYDIFSPIG 62 + SQ VE S+ S YVGD+EP+V + L FS G Sbjct: 161 ANSQGVEIVGSTLSGYVGDIEPTVPDFQLVKAFSEAG 197 >4YH8-A nrPDB Length = 216 Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 29/70 (41%) Query: 341 EFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK 400 EF+ YG + V G +V F E A AI + N + + +P+Y ++ Sbjct: 83 EFSKYGEVEQLVVCDNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPVYAELSPVT 142 Query: 401 DVRRSQLAQQ 410 D R + Q Sbjct: 143 DFREACCRQH 152 >5WU6-A nrPDB Length = 485 Score = 29.3 bits (64), Expect = 4.6, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 5/72 (6%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEAL 279 +++V + Q E F FGP+ S ++KD KG + A +AV + Sbjct: 5 SVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKD-----KGVFAIVEMGDVGAREAVLSQ 59 Query: 280 NDSELNGEKLYV 291 + L G +L V Sbjct: 60 SQHSLGGHRLRV 71 Score = 29.3 bits (64), Expect = 5.3, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 7/79 (8%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKG-FGFVHFEEEGAAKEA 182 G ++F+ D+D+ L + F FG + S + D K KG F V + G A+EA Sbjct: 2 GLRSVFVSGFPRDVDSAQLSEYFLAFGPVAS--VVMD---KDKGVFAIVEMGDVG-AREA 55 Query: 183 IDALNGMLLNGQEIYVAPH 201 + + + L G + V P Sbjct: 56 VLSQSQHSLGGHRLRVRPR 74 >2DGP-A nrPDB Length = 106 Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +FI + ++D K L F FG I + D G KG F+ + E +A +A AL Sbjct: 16 LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 75 Query: 187 N 187 + Sbjct: 76 H 76 >5XYB-A nrPDB Length = 396 Score = 28.9 bits (63), Expect = 6.5, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 5/50 (10%) Query: 169 GFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHY 218 F++F E AKE +D L+ ++ N E+ A H K R LE+ KA + Sbjct: 304 CFINFNENSKAKEVLDKLDLLVHNDNEL--AMHYYLKGR---LEQNKACF 348 >6GIQ-d nrPDB Length = 155 Score = 28.5 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLF-VKNLDDS 332 A N +E+NG + +G K+ L ++ RLE + K +G+++F K LD S Sbjct: 34 AQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEGIDVFDTKPLDSS 89 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6R5K-D nrPDB 813 0.0 1FXL-A nrPDB 191 6e-49 6AH0-4 nrPDB 190 1e-48 1FNX-H nrPDB 188 8e-48 3SXL-A nrPDB 184 7e-47 4EGL-A nrPDB 183 1e-46 5MMM-v nrPDB 173 2e-43 5EN1-A nrPDB 162 4e-40 4LMZ-A nrPDB 161 6e-40 3NNA-A nrPDB 161 1e-39 5ZWN-V nrPDB 158 5e-39 2CJK-A nrPDB 157 1e-38 5ZWM-4 nrPDB 156 2e-38 6ASO-A nrPDB 149 4e-36 1IFW-A nrPDB 138 5e-33 1JH4-A nrPDB 132 5e-31 1G9L-A nrPDB 130 2e-30 5OO6-B nrPDB 126 3e-29 6D0Y-A nrPDB 125 5e-29 2X04-A nrPDB 120 2e-27 1H6K-X nrPDB 118 8e-27 5EV3-A nrPDB 115 4e-26 2DH7-A nrPDB 109 4e-24 1D8Z-A nrPDB 108 8e-24 2SXL-A nrPDB 106 3e-23 2CQB-A nrPDB 105 4e-23 3MDF-A nrPDB 105 4e-23 5MQF-o nrPDB 104 1e-22 5ZWM-X nrPDB 104 1e-22 2KU7-A nrPDB 104 1e-22 5SZW-A nrPDB 103 2e-22 4FXV-A nrPDB 102 3e-22 6FF4-1 nrPDB 102 3e-22 3HI9-A nrPDB 101 7e-22 6GD1-A nrPDB 101 1e-21 2MYF-A nrPDB 100 2e-21 6QX9-R nrPDB 99 4e-21 1P1T-A nrPDB 98 8e-21 2ERR-A nrPDB 97 3e-20 2YWK-A nrPDB 96 4e-20 2DO0-A nrPDB 95 7e-20 1D9A-A nrPDB 94 1e-19 1SXL-A nrPDB 94 1e-19 2DH9-A nrPDB 94 1e-19 1NMR-A nrPDB 94 2e-19 4ZKA-A nrPDB 92 4e-19 2CQ3-A nrPDB 91 1e-18 1X5O-A nrPDB 90 2e-18 1P27-B nrPDB 90 3e-18 3EX7-B nrPDB 90 3e-18 2HYI-B nrPDB 89 4e-18 6C8U-1 nrPDB 89 4e-18 5YZG-w nrPDB 89 6e-18 2XS2-A nrPDB 89 7e-18 2J0Q-D nrPDB 89 7e-18 1OO0-B nrPDB 89 7e-18 2XS5-A nrPDB 88 9e-18 1RK8-A nrPDB 87 3e-17 2MGZ-B nrPDB 86 4e-17 3CW1-K nrPDB 82 4e-16 5X3Y-A nrPDB 81 2e-15 6QX9-1K nrPDB 80 2e-15 6G90-B nrPDB 80 3e-15 5ZWN-Q nrPDB 79 5e-15 2CPD-A nrPDB 78 1e-14 4WKR-A nrPDB 72 5e-13 Sequences not found previously or not previously below threshold: 4PKD-B nrPDB 89 7e-18 3NNH-A nrPDB 85 8e-17 2RS2-A nrPDB 85 1e-16 2LEC-A nrPDB 83 4e-16 2KN4-A nrPDB 81 1e-15 1UAW-A nrPDB 81 1e-15 2DH8-A nrPDB 81 2e-15 2DYD-A nrPDB 79 5e-15 2DGP-A nrPDB 77 2e-14 2EVZ-A nrPDB 77 2e-14 2DGQ-A nrPDB 77 2e-14 2DGS-A nrPDB 77 2e-14 1QM9-A nrPDB 76 3e-14 2MST-A nrPDB 76 5e-14 6AH0-p nrPDB 74 2e-13 2MKI-A nrPDB 71 1e-12 6EM1-o nrPDB 71 2e-12 4CQ1-A nrPDB 69 6e-12 1X4A-A nrPDB 67 2e-11 2I2Y-A nrPDB 67 2e-11 6FYY-r nrPDB 67 2e-11 6H7A-A nrPDB 67 2e-11 2BZ2-A nrPDB 66 4e-11 2CPE-A nrPDB 66 5e-11 6QX9-1A nrPDB 66 6e-11 6ID0-O nrPDB 65 1e-10 6QDV-M nrPDB 64 2e-10 1X5P-A nrPDB 63 3e-10 2F9J-A nrPDB 63 3e-10 6GML-X nrPDB 62 4e-10 5OPT-h nrPDB 62 4e-10 2LCW-A nrPDB 62 6e-10 2YTC-A nrPDB 62 6e-10 1I2T-A nrPDB 61 1e-09 2MMY-A nrPDB 61 2e-09 3JB9-Y nrPDB 61 2e-09 2LA6-A nrPDB 61 2e-09 5YVG-X nrPDB 60 2e-09 3JB9-k nrPDB 59 5e-09 2MKK-A nrPDB 59 6e-09 2CQH-A nrPDB 57 2e-08 5OSG-h nrPDB 57 3e-08 2RT3-A nrPDB 55 1e-07 2XNQ-A nrPDB 54 1e-07 5WSG-X nrPDB 53 3e-07 2M2B-A nrPDB 53 4e-07 2LKZ-A nrPDB 53 4e-07 2KVI-A nrPDB 52 5e-07 6FYY-p nrPDB 52 6e-07 3N9U-C nrPDB 52 1e-06 2LXI-A nrPDB 51 1e-06 5MDU-A nrPDB 51 1e-06 6D6V-H nrPDB 51 2e-06 3NS5-A nrPDB 51 2e-06 2RUG-A nrPDB 50 2e-06 3P6Y-C nrPDB 50 3e-06 5WU6-A nrPDB 50 4e-06 2CPI-A nrPDB 49 5e-06 3Q2T-C nrPDB 48 1e-05 2MQN-A nrPDB 48 1e-05 5K1H-B nrPDB 47 1e-05 5O20-A nrPDB 47 2e-05 5O1W-A nrPDB 47 2e-05 6FEC-u nrPDB 47 3e-05 3U1M-A nrPDB 46 4e-05 5LJ5-M nrPDB 46 5e-05 2E5G-A nrPDB 44 2e-04 2NLW-A nrPDB 44 2e-04 2KRB-A nrPDB 44 2e-04 4YH8-A nrPDB 44 2e-04 3S8S-A nrPDB 43 4e-04 1JMT-A nrPDB 42 0.001 4QU7-A nrPDB 40 0.002 4NOX-A nrPDB 40 0.002 5Z9X-A nrPDB 40 0.003 3DXB-A nrPDB 39 0.004 2VOD-A nrPDB 39 0.006 5ZWN-S nrPDB 39 0.008 2WBR-A nrPDB 38 0.011 2AD9-A nrPDB 38 0.014 1S79-A nrPDB 37 0.016 2PEH-A nrPDB 35 0.071 2DIU-A nrPDB 35 0.073 3ES8-A nrPDB 35 0.12 3D45-A nrPDB 34 0.14 3JB9-a nrPDB 34 0.14 2WAF-A nrPDB 33 0.30 2ROK-A nrPDB 33 0.30 1OWX-A nrPDB 33 0.40 6G90-A nrPDB 33 0.41 3CTR-A nrPDB 32 0.62 2DNR-A nrPDB 32 0.64 3COX-A nrPDB 32 0.67 2JBS-A nrPDB 32 0.79 5ZOK-B nrPDB 32 0.88 3LJS-A nrPDB 32 0.94 2O1T-A nrPDB 30 2.6 3TQS-A nrPDB 30 3.2 >6R5K-D nrPDB Length = 581 Score = 813 bits (2099), Expect = 0.0, Method: Composition-based stats. Identities = 577/577 (100%), Positives = 577/577 (100%) Query: 1 MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP 60 MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP Sbjct: 5 MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSP 64 Query: 61 IGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 120 IGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL Sbjct: 65 IGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 124 Query: 121 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK Sbjct: 125 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 184 Query: 181 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 240 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA Sbjct: 185 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 244 Query: 241 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 300 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER Sbjct: 245 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 304 Query: 301 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK 360 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK Sbjct: 305 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK 364 Query: 361 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ 420 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ Sbjct: 365 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ 424 Query: 421 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGP 480 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGP Sbjct: 425 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGP 484 Query: 481 VYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQ 540 VYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQ Sbjct: 485 VYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQ 544 Query: 541 EVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA 577 EVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA Sbjct: 545 EVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA 581 >1FXL-A nrPDB Length = 167 Score = 191 bits (486), Expect = 6e-49, Method: Composition-based stats. Identities = 53/167 (31%), Positives = 89/167 (53%), Gaps = 5/167 (2%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 S +L V L ++++ +F IG + S ++ RD IT SLGY +VN+ D + KA Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 96 IEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSS 155 I LN ++ + ++ +++ PS N+++ L + K L FS +G I++S Sbjct: 61 INTLNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 118 Query: 156 KIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNG--QEIYVA 199 +I D+ G S+G GF+ F++ A+EAI LNG +G + I V Sbjct: 119 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVK 165 Score = 184 bits (467), Expect = 1e-46, Method: Composition-based stats. Identities = 57/185 (30%), Positives = 89/185 (48%), Gaps = 22/185 (11%) Query: 217 HYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKA 275 TNL V + T E+F+ LF G I S L +D G+ G+GFVNY +DA KA Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 276 VEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDD 335 + LN L + + V A+ + A + NL+V L ++ Sbjct: 61 INTLNGLRLQTKTIKVSYARPSS------------------ASIRDANLYVSGLPKTMTQ 102 Query: 336 EKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAG--KPL 392 ++LE+ F+ YG I +++++ + G S+G GF+ F EA +AI N Q +G +P+ Sbjct: 103 KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPI 162 Query: 393 YVAIA 397 V A Sbjct: 163 TVKFA 167 Score = 156 bits (393), Expect = 3e-38, Method: Composition-based stats. Identities = 46/175 (26%), Positives = 88/175 (50%), Gaps = 12/175 (6%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 N+ + L ++ + F G+I S K+ D+ G+S G+GFV++ + A++A Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 183 IDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF 242 I+ LNG+ L + I V+ NLYV + T ++ ++LF+++ Sbjct: 61 INTLNGLRLQTKTIKVSYARPSSA--------SIRDANLYVSGLPKTMTQKELEQLFSQY 112 Query: 243 GPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNG--EKLYVGRA 294 G I+++ + D G +G GF+ ++K +A +A++ LN + +G E + V A Sbjct: 113 GRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFA 167 Score = 95.2 bits (235), Expect = 7e-20, Method: Composition-based stats. Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 NL V L ++ E+ F G I S K++R + G+S G+GFV + P++A KAI Sbjct: 3 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 62 Query: 381 EKNQQIVAGKPLYVAIAQR 399 N + K + V+ A+ Sbjct: 63 TLNGLRLQTKTIKVSYARP 81 >6AH0-4 nrPDB Length = 424 Score = 190 bits (483), Expect = 1e-48, Method: Composition-based stats. Identities = 65/178 (36%), Positives = 95/178 (53%), Gaps = 3/178 (1%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 S N A++YVG L+ VSE L+++F G V + + +D +T GY +V F E Sbjct: 7 SERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEED 66 Query: 92 GRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGD 151 AI+ +N + G+ R+ + G NIFI NL P+ID K LYDTFS FG Sbjct: 67 ADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVG-ANIFIGNLDPEIDEKLLYDTFSAFGV 125 Query: 152 IL-SSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKER 207 IL + KI D + G SKG+ F++F A+ AI+A+NG L + I V+ + + Sbjct: 126 ILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSK 183 Score = 189 bits (479), Expect = 4e-48, Method: Composition-based stats. Identities = 55/193 (28%), Positives = 101/193 (52%), Gaps = 20/193 (10%) Query: 214 TKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDA 272 + +YV ++ + ++ ELF + GP+V+ + KD G+ +G+GFV + EDA Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67 Query: 273 VKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDS 332 A++ +N +L G+ + V +A N+ + V G N+F+ NLD Sbjct: 68 DYAIKIMNMIKLYGKPIRVNKASAHNKNLDV-----------------GANIFIGNLDPE 110 Query: 333 VDDEKLEEEFAPYGTIT-SAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGK 390 +D++ L + F+ +G I + K+MR G SKG+ F+ F++ + + AI N Q + + Sbjct: 111 IDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNR 170 Query: 391 PLYVAIAQRKDVR 403 P+ V+ A +KD + Sbjct: 171 PITVSYAFKKDSK 183 Score = 155 bits (391), Expect = 6e-38, Method: Composition-based stats. Identities = 44/189 (23%), Positives = 86/189 (45%), Gaps = 10/189 (5%) Query: 115 QRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHF 173 P + +++ L + L++ F G ++++ + D G+ +G+GFV F Sbjct: 2 AAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEF 61 Query: 174 EEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDE 233 E A AI +N + L G+ I V + S + N+++ N++ E ++ Sbjct: 62 LSEEDADYAIKIMNMIKLYGKPIRV-------NKASAHNKNLDVGANIFIGNLDPEIDEK 114 Query: 234 QFQELFAKFGPIVSA-SLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYV 291 + F+ FG I+ + +D G KG+ F+N+ + + A+EA+N L + V Sbjct: 115 LLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITV 174 Query: 292 GRAQKKNER 300 A KK+ + Sbjct: 175 SYAFKKDSK 183 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Query: 28 SESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSI-RVCRDAITKTSLGYAYVNF 86 S + A++++G+L+P + E LYD FS G + ++ RD T S GYA++NF Sbjct: 90 SAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINF 149 Query: 87 NDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRK 122 +A AIE +N + R + ++ + S + Sbjct: 150 ASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGE 185 >1FNX-H nrPDB Length = 174 Score = 188 bits (476), Expect = 8e-48, Method: Composition-based stats. Identities = 50/173 (28%), Positives = 88/173 (50%), Gaps = 3/173 (1%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 +S +L V L ++++ +F IG + S ++ RD IT SLGY +VN++D K Sbjct: 2 DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADK 61 Query: 95 AIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS 154 AI LN ++ + ++ +++ PS N+++ L + K + FS +G I++ Sbjct: 62 AINTLNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIIT 119 Query: 155 SKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 S+I D+ G S+G GF+ F++ A+EAI LNG G + + Sbjct: 120 SRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNP 172 Score = 178 bits (452), Expect = 5e-45, Method: Composition-based stats. Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 22/189 (11%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAV 273 TNL V + T ++F+ LF G I S L +D G+ G+GFVNY DA Sbjct: 1 MDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 60 Query: 274 KAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSV 333 KA+ LN +L + + V A+ + A + NL+V L ++ Sbjct: 61 KAINTLNGLKLQTKTIKVSYARPSS------------------ASIRDANLYVSGLPKTM 102 Query: 334 DDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAG--K 390 +++E+ F+ YG I +++++ + G S+G GF+ F EA +AI N Q G + Sbjct: 103 SQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAE 162 Query: 391 PLYVAIAQR 399 P+ V A Sbjct: 163 PITVKFANN 171 Score = 154 bits (389), Expect = 1e-37, Method: Composition-based stats. Identities = 47/180 (26%), Positives = 88/180 (48%), Gaps = 12/180 (6%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 N+ + L ++ F GDI S K+ D+ G+S G+GFV++ + A +A Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 183 IDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF 242 I+ LNG+ L + I V+ NLYV + + ++ ++LF+++ Sbjct: 63 INTLNGLKLQTKTIKVSYARPSSA--------SIRDANLYVSGLPKTMSQKEMEQLFSQY 114 Query: 243 GPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNG--EKLYVGRAQKKNE 299 G I+++ + D A G +G GF+ ++K +A +A++ LN + G E + V A ++ Sbjct: 115 GRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQ 174 Score = 79.8 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 1/116 (0%) Query: 6 DKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVS 65 DK L L +Q + + S + A+LYV L ++S+ + +FS G + Sbjct: 60 DKAINTLNGLKLQTKTIKVSYARPSSASIRD-ANLYVSGLPKTMSQKEMEQLFSQYGRII 118 Query: 66 SIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLR 121 + R+ D T S G ++ F+ +AI+ LN G I + + Sbjct: 119 TSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQ 174 >3SXL-A nrPDB Length = 184 Score = 184 bits (468), Expect = 7e-47, Method: Composition-based stats. Identities = 48/169 (28%), Positives = 86/169 (50%), Gaps = 5/169 (2%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 S+ +L V L +++ LY +F IG +++ R+ RD T S GYA+V+F ++A Sbjct: 13 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRA 72 Query: 96 IEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSS 155 I+ LN ++ + ++ +++ P N+++ NL I + L F +G I+ Sbjct: 73 IKVLNGITVRNKRLKVSYAR--PGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQK 130 Query: 156 KIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNG--QEIYVAPH 201 I D+ G+ +G FV + + A+EAI ALN ++ G Q + V Sbjct: 131 NILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLA 179 Score = 178 bits (451), Expect = 6e-45, Method: Composition-based stats. Identities = 55/197 (27%), Positives = 96/197 (48%), Gaps = 22/197 (11%) Query: 206 ERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFV 264 E D + + +A TNL V + + TD + LF GPI + + +D G G+ FV Sbjct: 2 ESDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFV 61 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNL 324 ++ D+ +A++ LN + ++L V A+ E + + NL Sbjct: 62 DFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESI------------------KDTNL 103 Query: 325 FVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKN 383 +V NL ++ D++L+ F YG+I ++R + G+ +G FV ++ EEA +AI+ N Sbjct: 104 YVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALN 163 Query: 384 QQIVAG--KPLYVAIAQ 398 I G +PL V +A+ Sbjct: 164 NVIPEGGSQPLSVRLAE 180 Score = 162 bits (409), Expect = 5e-40, Method: Composition-based stats. Identities = 55/180 (30%), Positives = 89/180 (49%), Gaps = 12/180 (6%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEA 182 + N+ + L D+ ++ LY F G I + +I D + G S G+ FV F E ++ A Sbjct: 13 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRA 72 Query: 183 IDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF 242 I LNG+ + + + V+ E TNLYV N+ TD+Q +F K+ Sbjct: 73 IKVLNGITVRNKRLKVSYARPGGE--------SIKDTNLYVTNLPRTITDDQLDTIFGKY 124 Query: 243 GPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNG--EKLYVGRAQKKNE 299 G IV ++ +D G+ +G FV Y K E+A +A+ ALN+ G + L V A++ + Sbjct: 125 GSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGK 184 Score = 86.7 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 308 YEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGF 366 E+ L + NL V L + D +L F G I + ++MR + G S G+ F Sbjct: 1 MESDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAF 60 Query: 367 VCFSTPEEATKAITEKNQQIVAGKPLYVAIAQR 399 V F++ ++ +AI N V K L V+ A+ Sbjct: 61 VDFTSEMDSQRAIKVLNGITVRNKRLKVSYARP 93 >4EGL-A nrPDB Length = 177 Score = 183 bits (465), Expect = 1e-46, Method: Composition-based stats. Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 5/168 (2%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 3 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 62 Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKI 157 LN ++ + ++ +++ PS N++I L + K + D FS FG I++S++ Sbjct: 63 TLNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRV 120 Query: 158 ATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQ--EIYVAPHL 202 D+ G S+G F+ F++ A+EAI + NG G I V Sbjct: 121 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAA 168 Score = 176 bits (447), Expect = 2e-44, Method: Composition-based stats. Identities = 51/185 (27%), Positives = 87/185 (47%), Gaps = 22/185 (11%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++ + LF+ G + SA L +D G G+GFVNY +DA +A+ Sbjct: 3 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 62 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK 337 LN L + + V A+ +E + + NL++ L ++ + Sbjct: 63 TLNGLRLQSKTIKVSYARPSSEVI------------------KDANLYISGLPRTMTQKD 104 Query: 338 LEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAG--KPLYV 394 +E+ F+ +G I +++V+ + G S+G F+ F EA +AIT N G +P+ V Sbjct: 105 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 164 Query: 395 AIAQR 399 A Sbjct: 165 KFAAN 169 Score = 153 bits (386), Expect = 2e-37, Method: Composition-based stats. Identities = 46/175 (26%), Positives = 85/175 (48%), Gaps = 12/175 (6%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 G N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ A Sbjct: 1 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 60 Query: 183 IDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF 242 I+ LNG+ L + I V+ E NLY+ + T + +++F++F Sbjct: 61 INTLNGLRLQSKTIKVSYARPSSE--------VIKDANLYISGLPRTMTQKDVEDMFSRF 112 Query: 243 GPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNG--EKLYVGRA 294 G I+++ + D G +G F+ ++K +A +A+ + N + G E + V A Sbjct: 113 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFA 167 Score = 75.9 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 5/119 (4%) Query: 4 ITDKTAEQ----LENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFS 59 +T K AE+ L L +Q + + S V A+LY+ L ++++ + D+FS Sbjct: 52 VTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKD-ANLYISGLPRTMTQKDVEDMFS 110 Query: 60 PIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDP 118 G + + RV D T S G A++ F+ +AI N G I Sbjct: 111 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAAN 169 >5MMM-v nrPDB Length = 260 Score = 173 bits (439), Expect = 2e-43, Method: Composition-based stats. Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 6/181 (3%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 LYV NI +++ + + + G I A + D G+ + FGFV + EDA +E Sbjct: 84 RRLYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIE 143 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK 337 LND+E+ G K+ V +K E M + Q E + + +++ NL +V +E Sbjct: 144 KLNDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVES----PYKVYIGNLAKTVTNEL 199 Query: 338 LEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAI 396 L++ F+ G + AKV RT KS GFGFV FS+ EE AI N ++ G+ + V Sbjct: 200 LKDFFSEKGKVLGAKVQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRVNK 259 Query: 397 A 397 A Sbjct: 260 A 260 Score = 141 bits (355), Expect = 9e-34, Method: Composition-based stats. Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 13/178 (7%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 + LYVG++ +++ L I G++ V D + S + +V E I Sbjct: 83 ARRLYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVI 142 Query: 97 EQLNYTPIKGRLCRIM------------WSQRDPSLRKKGSGNIFIKNLHPDIDNKALYD 144 E+LN T I GR ++ +Q + S + ++I NL + N+ L D Sbjct: 143 EKLNDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVESPYKVYIGNLAKTVTNELLKD 202 Query: 145 TFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPH 201 FS G +L +K+ KS GFGFV F E + AI ALN +L GQ+I V Sbjct: 203 FFSEKGKVLGAKVQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRVNKA 260 Score = 107 bits (267), Expect = 1e-23, Method: Composition-based stats. Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 6/107 (5%) Query: 8 TAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSI 67 T + LE ++I Q + +SQ VE S +Y+G+L +V+ L D FS G V Sbjct: 160 TEKPLEGMDIATTQAE-----DSQFVE-SPYKVYIGNLAKTVTNELLKDFFSEKGKVLGA 213 Query: 68 RVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWS 114 +V R T S G+ +V+F+ E AI+ LN + ++G+ R+ + Sbjct: 214 KVQRTPGTSKSNGFGFVSFSSEEEVEAAIQALNNSVLEGQKIRVNKA 260 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 L+V N+ ++++++L +G I A+VM + +G+S+ FGFV T E+A I Sbjct: 84 RRLYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIE 143 Query: 381 EKNQQIVAGKPLYVAIAQR----KDVRRSQ 406 + N + G+ + V I ++ D+ +Q Sbjct: 144 KLNDTEIGGRKIKVNITEKPLEGMDIATTQ 173 >5EN1-A nrPDB Length = 184 Score = 162 bits (410), Expect = 4e-40, Method: Composition-based stats. Identities = 46/174 (26%), Positives = 77/174 (44%), Gaps = 7/174 (4%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 L++G L +E L + + G ++ V RD +K S G+ +V F+ A+ Sbjct: 10 RKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMA 69 Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKKGSG----NIFIKNLHPDIDNKALYDTFSVFGDIL 153 ++ I GR+ + K G+ +F+ + D + L D F +G I Sbjct: 70 ARPHS-IDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKID 128 Query: 154 SSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 + +I TD ++GK +GFGFV F++ I +NG V LSR+E Sbjct: 129 TIEIITDRQSGKKRGFGFVTFDDHDPVD-KIVLQKYHTINGHNAEVRKALSRQE 181 Score = 138 bits (348), Expect = 6e-33, Method: Composition-based stats. Identities = 40/175 (22%), Positives = 77/175 (44%), Gaps = 15/175 (8%) Query: 214 TKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDA 272 K + L++ ++ ETT+E + + ++G + + +D A + +GFGFV + + Sbjct: 5 EKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEV 64 Query: 273 VKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDS 332 A+ A ++G + RA + E A LFV + + Sbjct: 65 DAAMAA-RPHSIDGRVVEPKRAVAREESGK------------PGAHVTVKKLFVGGIKED 111 Query: 333 VDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKAITEKNQQI 386 ++ L + F YG I + +++ ++GK +GFGFV F + K + +K I Sbjct: 112 TEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTI 166 Score = 129 bits (325), Expect = 3e-30, Method: Composition-based stats. Identities = 44/186 (23%), Positives = 77/186 (41%), Gaps = 6/186 (3%) Query: 117 DPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGK-SKGFGFVHFEE 175 K+ +FI L + ++L + + +G + + D K S+GFGFV F Sbjct: 1 RKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSS 60 Query: 176 EGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQF 235 A+ A ++G+ V P + +S L+V I +T + Sbjct: 61 MAEVDAAMAA-RPHSIDGR--VVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHL 117 Query: 236 QELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRA 294 ++ F ++G I + + D GK +GFGFV ++ H D V + +NG V +A Sbjct: 118 RDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDH-DPVDKIVLQKYHTINGHNAEVRKA 176 Query: 295 QKKNER 300 + E Sbjct: 177 LSRQEM 182 Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK-SKGFGFVCFSTPE 373 K K Q LF+ L +E L + +G +T VMR K S+GFGFV FS+ Sbjct: 3 KREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMA 62 Query: 374 EATKAITE 381 E A+ Sbjct: 63 EVDAAMAA 70 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 45/111 (40%), Gaps = 1/111 (0%) Query: 12 LENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCR 71 ++ ++ + A S + L+VG ++ E HL D F G + +I + Sbjct: 75 IDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIIT 134 Query: 72 DAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRK 122 D + G+ +V F+DH+ K I Y I G + + +++ Sbjct: 135 DRQSGKKRGFGFVTFDDHDPVDK-IVLQKYHTINGHNAEVRKALSRQEMQE 184 >4LMZ-A nrPDB Length = 180 Score = 161 bits (408), Expect = 6e-40, Method: Composition-based stats. Identities = 42/184 (22%), Positives = 79/184 (42%), Gaps = 20/184 (10%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG---KLKGFGFVNYEKHEDAVKAV 276 ++V I ++++ +ELF +G + ++ +D + KG FV + + A++A Sbjct: 10 KMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 69 Query: 277 EALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDE 336 AL++ + Q + EK + LF+ + ++ Sbjct: 70 NALHNIK----------TLPGMH----HPIQMKPADSEKSNAVEDRKLFIGMVSKKCNEN 115 Query: 337 KLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQ-QIVAG--KPLY 393 + F+P+G I +++R +G S+G FV FST A AI +Q Q + G P+ Sbjct: 116 DIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIV 175 Query: 394 VAIA 397 V A Sbjct: 176 VKFA 179 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 4/162 (2%) Query: 30 SQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK--TSLGYAYVNFN 87 ++ + ++VG + S SE L ++F P G+V I V RD S G +V F Sbjct: 1 GSHMDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFY 60 Query: 88 DHEAGRKAIEQL-NYTPIKGRLCRI-MWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDT 145 +A +A L N + G I M +FI + + + Sbjct: 61 TRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVM 120 Query: 146 FSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 FS FG I +I +G S+G FV F A+ AI A++ Sbjct: 121 FSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMH 162 Score = 157 bits (396), Expect = 2e-38, Method: Composition-based stats. Identities = 40/183 (21%), Positives = 78/183 (42%), Gaps = 12/183 (6%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENG---KSKGFGFVHFEE 175 S + +F+ + K L + F +G + + D + +SKG FV F Sbjct: 2 SHMDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYT 61 Query: 176 EGAAKEAIDALNGM-LLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQ 234 AA EA +AL+ + L G + + E+ + +E+ K L++ ++ + + Sbjct: 62 RKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRK-----LFIGMVSKKCNEND 116 Query: 235 FQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELN---GEKLYV 291 + +F+ FG I + + DG +G FV + A A++A++ S+ + V Sbjct: 117 IRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVV 176 Query: 292 GRA 294 A Sbjct: 177 KFA 179 Score = 62.0 bits (149), Expect = 8e-10, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 9/98 (9%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENG---KSKGFGFVCFSTPEE 374 + +FV + S +++L+E F PYG + V+R + +SKG FV F T + Sbjct: 5 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 64 Query: 375 ATKAITEKNQQI-VAG--KPLYVAIAQRKDVRRSQLAQ 409 A +A + + G P+ + A D +S + Sbjct: 65 ALEAQNALHNIKTLPGMHHPIQMKPA---DSEKSNAVE 99 >3NNA-A nrPDB Length = 175 Score = 161 bits (406), Expect = 1e-39, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 20/188 (10%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG---KLKGFGFVNYEKHEDA 272 + ++V + +++ +ELF ++G + ++ +D + KG FV + + A Sbjct: 1 SDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAA 60 Query: 273 VKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDS 332 ++A AL++ ++ MH Q + EK + LF+ + Sbjct: 61 LEAQNALHNMKV-------------LPGMH-HPIQMKPADSEKNNAVEDRKLFIGMISKK 106 Query: 333 VDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQ-QIVAG-- 389 + + F+ +G I +++R +G S+G FV F+T A AI +Q Q + G Sbjct: 107 CTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCS 166 Query: 390 KPLYVAIA 397 P+ V A Sbjct: 167 SPMVVKFA 174 Score = 159 bits (401), Expect = 4e-39, Method: Composition-based stats. Identities = 41/153 (26%), Positives = 61/153 (39%), Gaps = 4/153 (2%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK--TSLGYAYVNFNDHEAGRKAI 96 ++VG + + SE L ++F G+V I V RD S G +V F +A +A Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 97 EQL-NYTPIKGRLCRI-MWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS 154 L N + G I M +FI + + FS FG I Sbjct: 65 NALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEE 124 Query: 155 SKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 +I +G S+G FV F A+ AI A++ Sbjct: 125 CRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMH 157 Score = 158 bits (400), Expect = 5e-39, Method: Composition-based stats. Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENG---KSKGFGFVHFEEEGAAK 180 + +F+ + K L + F +G + + D + +SKG FV F AA Sbjct: 2 DAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAAL 61 Query: 181 EAIDALNGM-LLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELF 239 EA +AL+ M +L G + + E+++ +E+ K L++ I+ + T+ + +F Sbjct: 62 EAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRK-----LFIGMISKKCTENDIRVMF 116 Query: 240 AKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSE 283 + FG I + + DG +G FV + A A++A++ ++ Sbjct: 117 SSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQ 160 Score = 66.3 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 21 QKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLG 80 Q + A ++ +VE+ L++G + +E + +FS G + R+ R S G Sbjct: 81 QMKPADSEKNNAVED--RKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPD-GLSRG 137 Query: 81 YAYVNFNDHEAGRKAIEQLN 100 A+V F + AI+ ++ Sbjct: 138 CAFVTFTTRAMAQTAIKAMH 157 >5ZWN-V nrPDB Length = 523 Score = 158 bits (400), Expect = 5e-39, Method: Composition-based stats. Identities = 60/352 (17%), Positives = 118/352 (33%), Gaps = 72/352 (20%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDI-LSSKIATDEN-----------GKSKGFGFVHFEE 175 +++ +L P D + ++ G+ ++ ++ + ++G+ FV F Sbjct: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 Query: 176 EGAAKEAIDALNGMLLNG---QEIYVAPHLSRKERDSQLEETKAHY--TNLYVKNINSET 230 A A+ NGML+ +++ + S + +++V ++ Sbjct: 116 STHAANALLK-NGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNV 174 Query: 231 TDEQFQELF-AKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEK 288 T+ Q ELF ++ A + D G KG+GFV + ++ A+ + LNG Sbjct: 175 TESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRA 234 Query: 289 LYV---------------------------------------------GRAQKKNERMHV 303 + V K+N Sbjct: 235 IKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQF 294 Query: 304 LKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKG 363 + + L +F+ L V +++L F P+GTI K+ GK Sbjct: 295 IYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKI---PVGKC-- 349 Query: 364 FGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARN 415 GFV + A AI +A + ++ + +++ L QQ N Sbjct: 350 CGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGR--SAKQTALLQQAMLSN 399 Score = 99.4 bits (246), Expect = 4e-21, Method: Composition-based stats. Identities = 43/233 (18%), Positives = 85/233 (36%), Gaps = 67/233 (28%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFS-PIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 ++ S++VGDL P+V+E+ L+++F S S ++ D +T S GY +V F + + + Sbjct: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 Query: 95 AIEQLNYTPIKGRLCRIMWSQR-----------DPSLRKKGSGNI----------FIKNL 133 A+ ++ + GR ++ + + S + N+ F+ N Sbjct: 221 ALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNG 280 Query: 134 HPDI----------------------------------------DNKALYDTFSVFGDIL 153 + ++ L F FG I+ Sbjct: 281 NNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIV 340 Query: 154 SSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 KI K GFV + + +A+ AI + G + + ++ S K+ Sbjct: 341 YVKIPVG-----KCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQ 388 >2CJK-A nrPDB Length = 167 Score = 157 bits (397), Expect = 1e-38, Method: Composition-based stats. Identities = 51/178 (28%), Positives = 87/178 (48%), Gaps = 13/178 (7%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKE 181 K S +FI L+ D L + F +G + KI D G+S+GFGF+ FE+ + E Sbjct: 1 KESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDE 60 Query: 182 AIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAK 241 + + +L+G+ I + R E+D ++V I + ++F+E F++ Sbjct: 61 VVKTQH--ILDGKVIDPKRAIPRDEQDKT--------GKIFVGGIGPDVRPKEFEEFFSQ 110 Query: 242 FGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 +G I+ A L D G+ +GFGFV Y+ DAV V + K+ + RA+ ++ Sbjct: 111 WGTIIDAQLMLDKDTGQSRGFGFVTYDS-ADAVDRVCQNKFIDFKDRKIEIKRAEPRH 167 Score = 155 bits (391), Expect = 6e-38, Method: Composition-based stats. Identities = 37/171 (21%), Positives = 82/171 (47%), Gaps = 6/171 (3%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 S +++G L +E +L + F G+V+ +++ +D T S G+ +++F + + Sbjct: 1 KESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDE 60 Query: 95 AIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS 154 ++ + + G++ I + P + +G IF+ + PD+ K + FS +G I+ Sbjct: 61 VVKTQHI--LDGKV--IDPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFEEFFSQWGTIID 116 Query: 155 SKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSR 204 +++ D+ G+S+GFGFV ++ A + ++I + R Sbjct: 117 AQLMLDKDTGQSRGFGFVTYDSADAVDRVCQN-KFIDFKDRKIEIKRAEPR 166 Score = 138 bits (348), Expect = 5e-33, Method: Composition-based stats. Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 23/187 (12%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVK 274 +++ +N +TT++ +E F K+G + + KD A G+ +GFGF+++EK + Sbjct: 1 KESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDE 60 Query: 275 AVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVD 334 V+ L+G+ + RA ++E+ + +FV + V Sbjct: 61 VVKT--QHILDGKVIDPKRAIPRDEQ------------------DKTGKIFVGGIGPDVR 100 Query: 335 DEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLY 393 ++ EE F+ +GTI A++M + G+S+GFGFV + + + + K + + Sbjct: 101 PKEFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKF-IDFKDRKIE 159 Query: 394 VAIAQRK 400 + A+ + Sbjct: 160 IKRAEPR 166 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 42/108 (38%), Gaps = 7/108 (6%) Query: 7 KTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSS 66 KT L+ I + ++ + ++VG + P V + FS G++ Sbjct: 63 KTQHILDGKVIDPKRAIPRD------EQDKTGKIFVGGIGPDVRPKEFEEFFSQWGTIID 116 Query: 67 IRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWS 114 ++ D T S G+ +V ++ +A + + + K R I + Sbjct: 117 AQLMLDKDTGQSRGFGFVTYDSADAVDRVCQN-KFIDFKDRKIEIKRA 163 >5ZWM-4 nrPDB Length = 213 Score = 156 bits (395), Expect = 2e-38, Method: Composition-based stats. Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 13/190 (6%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 +S ++YVG+++P +++ LY++F I V I+ +D + + GYA++ F + + Sbjct: 5 ADSGNTVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQ 64 Query: 94 KAIEQLNYT-PIKGRLCRI------MWSQRDPSLRKKGS----GNIFIKNLHPDIDNKAL 142 AI+ +N T + RL ++ + PS K +FIKNL ID+ L Sbjct: 65 YAIKIMNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIKNLADSIDSDQL 124 Query: 143 YDTFSVFGD-ILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPH 201 F+ FG I +I NGK K +V+FE+ A AI +LN L+ I V Sbjct: 125 VKIFNKFGKLIREPEIFYLSNGKLK-CAYVYFEDFEKADLAIKSLNNQLVANNRITVDYA 183 Query: 202 LSRKERDSQL 211 + + Sbjct: 184 FKENGKGNAK 193 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 8/195 (4%) Query: 211 LEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKH 269 + + +YV NI+ T EQ ELF + P++ KD +G+ F+ + Sbjct: 1 MNYSADSGNTVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQ 60 Query: 270 EDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNL 329 DA A++ +N++ ++L R + L + +AK LF+KNL Sbjct: 61 GDAQYAIKIMNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAK-----LFIKNL 115 Query: 330 DDSVDDEKLEEEFAPYGT-ITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVA 388 DS+D ++L + F +G I ++ NGK K +V F E+A AI N Q+VA Sbjct: 116 ADSIDSDQLVKIFNKFGKLIREPEIFYLSNGKLK-CAYVYFEDFEKADLAIKSLNNQLVA 174 Query: 389 GKPLYVAIAQRKDVR 403 + V A +++ + Sbjct: 175 NNRITVDYAFKENGK 189 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 47/198 (23%), Positives = 89/198 (44%), Gaps = 8/198 (4%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKS-KGFGFVHFEEEGAAKEAIDA 185 +++ N+ P I + LY+ F +L K D+ ++ +G+ F+ F +G A+ AI Sbjct: 10 TVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIKI 69 Query: 186 LNGM-LLNGQEIYVAP----HLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 240 +N L + I V + + ++ L++KN+ +Q ++F Sbjct: 70 MNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIKNLADSIDSDQLVKIFN 129 Query: 241 KFGP-IVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNE 299 KFG I + ++GKLK +V +E E A A+++LN+ + ++ V A K+N Sbjct: 130 KFGKLIREPEIFYLSNGKLK-CAYVYFEDFEKADLAIKSLNNQLVANNRITVDYAFKENG 188 Query: 300 RMHVLKKQYEAYRLEKMA 317 + + L K A Sbjct: 189 KGNAKYGDDVDRLLNKEA 206 >6ASO-A nrPDB Length = 424 Score = 149 bits (375), Expect = 4e-36, Method: Composition-based stats. Identities = 67/338 (19%), Positives = 134/338 (39%), Gaps = 42/338 (12%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 + +L++ + PS ++ ++ D+ I V+ SIR+ TS +AY++ E R Sbjct: 89 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRF-NTSRRFAYIDVTSKEDARY 147 Query: 95 AIEQLNYTPIKG------RLCRIMWSQRDPSLRKKGSGNIFIKNLHPD-IDNKALYDTFS 147 +E+LN I+G + S+R S +G I I+NL + +D L ++F Sbjct: 148 CVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEG-REIMIRNLSTELLDENLLRESFE 206 Query: 148 VFGDILSSKIA--TDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRK 205 FG I I E+ + F+ FE + +A+ A+ +N LL +EI V+ + Sbjct: 207 GFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKKP 265 Query: 206 ERDSQLEETKAHYTN---------LYVKNINSETTDEQF-----QELFAKFGPIVSASLE 251 + + N L+ ++ + + +E+ I L Sbjct: 266 FLERNEVKRLLASRNSKELETLICLFP--LSDKVSPSLICQFLQEEIHINEKDIRKILLV 323 Query: 252 KDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLY---VGRAQKKNERMHVLKKQY 308 D +G + + + A K + LN S+ G+ + + ++ ++ Sbjct: 324 SDFNG-----AIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTINDMKRYYNNQQNHSMKH 378 Query: 309 EAYRLEKMAKYQGVNLFVK----NLDDSVDDEKLEEEF 342 M + +G NL VK + + + ++ + F Sbjct: 379 VKPSCINMME-KGPNLQVKKKIPDKQEQMSNDDFRKMF 415 Score = 123 bits (308), Expect = 2e-28, Method: Composition-based stats. Identities = 58/300 (19%), Positives = 114/300 (38%), Gaps = 34/300 (11%) Query: 121 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 R + + +KNL + +Y F G I+ +A D K+ F + F A Sbjct: 10 RNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVA-DSLKKNFRFARIEFARYDGAL 68 Query: 181 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 240 AI + ++ EI V+ L++ N T ++L Sbjct: 69 AAITKTH-KVVGQNEIIVSHLTE---------------CTLWMTNFPPSYTQRNIRDLLQ 112 Query: 241 KFGPI-VSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNE 299 + +S L + F +++ EDA VE LN ++ G L + Sbjct: 113 DINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNP--- 169 Query: 300 RMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDS-VDDEKLEEEFAPYGTITSAKVMRTEN 358 E + A +G + ++NL +D+ L E F +G+I + + Sbjct: 170 --------LEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQK 221 Query: 359 GKS--KGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKD-VRRSQLAQQIQARN 415 S F+ F + A +A+ N+ ++ + + V++A +K + R+++ + + +RN Sbjct: 222 EHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKKPFLERNEVKRLLASRN 280 Score = 107 bits (267), Expect = 2e-23, Method: Composition-based stats. Identities = 58/374 (15%), Positives = 135/374 (36%), Gaps = 31/374 (8%) Query: 29 ESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFND 88 E+ + ++ V +L S ++ +Y F G + + V K + +A + F Sbjct: 6 EALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVA--DSLKKNFRFARIEFAR 63 Query: 89 HEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSV 148 ++ AI + + + + + +++ N P + + D Sbjct: 64 YDGALAAITKTHKVVGQNEII----------VSHLTECTLWMTNFPPSYTQRNIRDLLQD 113 Query: 149 FGDI-LSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKER 207 + LS ++ + S+ F ++ + A+ ++ LNG+ + G + V + E+ Sbjct: 114 INVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTL-VTKVSNPLEK 172 Query: 208 DSQLEETKAHYTNLYVKNINSE-TTDEQFQELFAKFGPIVSASLEKDADGKLKG--FGFV 264 + + + ++N+++E + +E F FG I ++ F+ Sbjct: 173 SKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFM 232 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNL 324 +E + A +A+ +N S L ++ V A KK + + + + + +K + Sbjct: 233 VFENKDSAERAL-QMNRSLLGNREISVSLADKKP---FLERNEVKRLLASRNSKELETLI 288 Query: 325 FVKNLDDSVDDEKLEEEFAPYGTITSAKV-----MRTENGKSKGFGFVCFSTPEEATKAI 379 + L D V + + I + + NG + F + A K + Sbjct: 289 CLFPLSDKVSPSLICQFLQEEIHINEKDIRKILLVSDFNG-----AIIIFRDSKFAAKML 343 Query: 380 TEKNQQIVAGKPLY 393 N GK + Sbjct: 344 MILNGSQFQGKVIR 357 Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 27/213 (12%), Positives = 72/213 (33%), Gaps = 28/213 (13%) Query: 206 ERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVN 265 ++ ++ T + VKN+ + + F GPI+ + D+ K F + Sbjct: 2 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVA-DSLKKNFRFARIE 60 Query: 266 YEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLF 325 + +++ A+ A+ + + ++ V L+ Sbjct: 61 FARYDGALAAITKTH-KVVGQNEIIVSH-------------------------LTECTLW 94 Query: 326 VKNLDDSVDDEKLEEEFAPYGTI-TSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQ 384 + N S + + + S ++ S+ F ++ ++ E+A + + N Sbjct: 95 MTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNG 154 Query: 385 QIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQM 417 + G L ++ + + + ++ R M Sbjct: 155 LKIEGYTLVTKVSNPLEKSKRTDSATLEGREIM 187 >1IFW-A nrPDB Length = 92 Score = 138 bits (348), Expect = 5e-33, Method: Composition-based stats. Identities = 88/89 (98%), Positives = 88/89 (98%) Query: 489 GFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES 548 G PRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES Sbjct: 4 GSPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES 63 Query: 549 DELFEQHYKEASAAYESFKKEQEQQTEQA 577 DELFEQHYKEASAAYESFKKEQEQQTEQA Sbjct: 64 DELFEQHYKEASAAYESFKKEQEQQTEQA 92 >1JH4-A nrPDB Length = 98 Score = 132 bits (331), Expect = 5e-31, Method: Composition-based stats. Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Query: 489 GFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLES 548 G P A+ Q+Q+Q LGE+L+ + A + AGKITGM+L++ E+ +LES Sbjct: 4 GSPLTASMLASAPPQEQKQMLGERLFPLIQAM--HPTLAGKITGMLLEIDNSELLHMLES 61 Query: 549 DELFEQHYKEASAAYESFKKEQEQQ 573 E EA A ++ + ++ Q Sbjct: 62 PESLRSKVDEAVAVLQAHQAKEAAQ 86 >1G9L-A nrPDB Length = 144 Score = 130 bits (326), Expect = 2e-30, Method: Composition-based stats. Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 18/147 (12%) Query: 427 AAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGPVYGVPP 486 +AAA P P + R NPQQ N P P V Sbjct: 4 GSAAAATPAVRTVPQYKYAAGVR-------NPQQH-------LNAQPQVTMQQPAVHV-- 47 Query: 487 QGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLL 546 QG P A+ Q+Q+Q LGE+L+ + A + AGKITGM+L++ E+ +L Sbjct: 48 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAM--HPTLAGKITGMLLEIDNSELLHML 105 Query: 547 ESDELFEQHYKEASAAYESFKKEQEQQ 573 ES E EA A ++ + ++ Q Sbjct: 106 ESPESLRSKVDEAVAVLQAHQAKEAAQ 132 >5OO6-B nrPDB Length = 158 Score = 126 bits (316), Expect = 3e-29, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 49/108 (45%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 DQ E + + S +LYVG+L +E +Y++FS G + I + D + KT+ Sbjct: 24 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTAC 83 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGN 127 G+ +V + A+ +N T + R+ R W R+ G G Sbjct: 84 GFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGR 131 Score = 95.9 bits (237), Expect = 4e-20, Method: Composition-based stats. Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 7/116 (6%) Query: 185 ALNGMLLNG--QEIYVAPHLSRKER----DSQLEETKAHYTNLYVKNINSETTDEQFQEL 238 A++G LL + YV R + + + E+ LYV N++ TT+EQ EL Sbjct: 2 AMSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYEL 61 Query: 239 FAKFGPIVSASLEKDADGKL-KGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGR 293 F+K G I + D K GF FV Y DA A+ +N + L+ + Sbjct: 62 FSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDW 117 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSK-GFGFVHFEEEGAAKE 181 K S +++ NL + +Y+ FS GDI + D+ K+ GF FV + A+ Sbjct: 39 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAEN 98 Query: 182 AIDALNGMLLNGQEIY 197 A+ +NG L+ + I Sbjct: 99 AMRYINGTRLDDRIIR 114 Score = 65.1 bits (157), Expect = 7e-11, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 45/109 (41%), Gaps = 7/109 (6%) Query: 290 YVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTIT 349 YV +Q +++ H E +L K + L+V NL +E++ E F+ G I Sbjct: 16 YVELSQYRDQ--HFRGDNEEQEKLLK----KSCTLYVGNLSFYTTEEQIYELFSKSGDIK 69 Query: 350 SAKVMRTENGKS-KGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIA 397 + + K+ GF FV + + +A A+ N + + + Sbjct: 70 KIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWD 118 >6D0Y-A nrPDB Length = 176 Score = 125 bits (314), Expect = 5e-29, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 49/108 (45%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 DQ E + + S +LYVG+L +E +Y++FS G + I + D + KT+ Sbjct: 42 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTAC 101 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGN 127 G+ +V + A+ +N T + R+ R W R+ G G Sbjct: 102 GFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGR 149 Score = 99.0 bits (245), Expect = 5e-21, Method: Composition-based stats. Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 7/120 (5%) Query: 181 EAIDALNGMLLNG--QEIYVAPHLSRKER----DSQLEETKAHYTNLYVKNINSETTDEQ 234 EA D ++G LL + YV R + + + E+ LYV N++ TT+EQ Sbjct: 16 EAADPMSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQ 75 Query: 235 FQELFAKFGPIVSASLEKDADGKL-KGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGR 293 ELF+K G I + D K GF FV Y DA A+ +N + L+ + Sbjct: 76 IYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDW 135 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSK-GFGFVHFEEEGAAKE 181 K S +++ NL + +Y+ FS GDI + D+ K+ GF FV + A+ Sbjct: 57 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAEN 116 Query: 182 AIDALNGMLLNGQEIY 197 A+ +NG L+ + I Sbjct: 117 AMRYINGTRLDDRIIR 132 Score = 64.7 bits (156), Expect = 9e-11, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 33/79 (41%), Gaps = 1/79 (1%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKS-KGFGFVCFSTPEEATKA 378 + L+V NL +E++ E F+ G I + + K+ GF FV + + +A A Sbjct: 58 KSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENA 117 Query: 379 ITEKNQQIVAGKPLYVAIA 397 + N + + + Sbjct: 118 MRYINGTRLDDRIIRTDWD 136 >2X04-A nrPDB Length = 80 Score = 120 bits (300), Expect = 2e-27, Method: Composition-based stats. Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 2/77 (2%) Query: 492 RNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDEL 551 A+ Q+Q+Q LGE+L+ + A + AGKITGM+L++ E+ +LES E Sbjct: 6 LTASMLASAPPQEQKQMLGERLFPLIQAM--HPTLAGKITGMLLEIDNSELLHMLESPES 63 Query: 552 FEQHYKEASAAYESFKK 568 EA A ++ + Sbjct: 64 LRSKVDEAVAVLQAHQA 80 >1H6K-X nrPDB Length = 98 Score = 118 bits (295), Expect = 8e-27, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 DQ E + + S +LYVG+L +E +Y++FS G + I + D + KT+ Sbjct: 1 DQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKM-KTAC 59 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDP 118 G+ +V + A+ +N T + R+ R W Sbjct: 60 GFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK 98 Score = 95.9 bits (237), Expect = 4e-20, Method: Composition-based stats. Identities = 26/89 (29%), Positives = 40/89 (44%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFV 264 + + + E+ LYV N++ TT+EQ ELF+K G I + D GF FV Sbjct: 5 RGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFV 64 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGR 293 Y DA A+ +N + L+ + Sbjct: 65 EYYSRADAENAMRYINGTRLDDRIIRTDW 93 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 36/75 (48%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 K S +++ NL + +Y+ FS GDI + D+ + GF FV + A+ A Sbjct: 16 KKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFVEYYSRADAENA 75 Query: 183 IDALNGMLLNGQEIY 197 + +NG L+ + I Sbjct: 76 MRYINGTRLDDRIIR 90 Score = 68.6 bits (166), Expect = 8e-12, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 32/78 (41%) Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAI 379 + L+V NL +E++ E F+ G I + + + GF FV + + +A A+ Sbjct: 17 KSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKTACGFCFVEYYSRADAENAM 76 Query: 380 TEKNQQIVAGKPLYVAIA 397 N + + + Sbjct: 77 RYINGTRLDDRIIRTDWD 94 >5EV3-A nrPDB Length = 201 Score = 115 bits (289), Expect = 4e-26, Method: Composition-based stats. Identities = 46/207 (22%), Positives = 85/207 (41%), Gaps = 32/207 (15%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFS-----------VFGDILSSKIATDENGKSKG 167 S + + +++ N+ I +A+ D F+ +L+ +I D+N Sbjct: 2 SQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN----- 56 Query: 168 FGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYT-------- 219 F F+ F +A+ A +G++ GQ + + + + E + Y Sbjct: 57 FAFLEFRSVDETTQAM-AFDGIIFQGQSLKIRRPHDYQP-LPGMSENPSVYVPGVVSTVV 114 Query: 220 -----NLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAV 273 L++ + + D+Q +EL FGP+ + +L KD A G KG+ F Y Sbjct: 115 PDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTD 174 Query: 274 KAVEALNDSELNGEKLYVGRAQKKNER 300 +A+ LN +L +KL V RA + Sbjct: 175 QAIAGLNGMQLGDKKLLVQRASVGAKN 201 Score = 98.3 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 38/196 (19%), Positives = 76/196 (38%), Gaps = 20/196 (10%) Query: 216 AHYTNLYVKNINSETTDEQFQELF-----------AKFGPIVSASLEKDADGKLKGFGFV 264 LYV NI T+E + F A P+++ + +D + F F+ Sbjct: 6 RQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN-----FAFL 60 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRA--QKKNERMHVLKKQYEAYRLEKMAKYQGV 322 + ++ +A+ A + G+ L + R + M Y + + Sbjct: 61 EFRSVDETTQAM-AFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAH 119 Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 LF+ L + ++D++++E +G + + +++ G SKG+ F + +AI Sbjct: 120 KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAG 179 Query: 382 KNQQIVAGKPLYVAIA 397 N + K L V A Sbjct: 180 LNGMQLGDKKLLVQRA 195 Score = 94.8 bits (234), Expect = 1e-19, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 80/203 (39%), Gaps = 37/203 (18%) Query: 30 SQSVENSSASLYVGDLEPSVSEAHLYDIF-----------SPIGSVSSIRVCRDAITKTS 78 + + LYVG++ ++E + D F +P V ++++ +D Sbjct: 1 GSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN---- 56 Query: 79 LGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRI---------MWSQRDPSLRKKG----- 124 +A++ F + +A+ + +G+ +I +PS+ G Sbjct: 57 --FAFLEFRSVDETTQAM-AFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTV 113 Query: 125 ----SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAA 179 + +FI L +++ + + + FG + + + D G SKG+ F + + Sbjct: 114 VPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVT 173 Query: 180 KEAIDALNGMLLNGQEIYVAPHL 202 +AI LNGM L +++ V Sbjct: 174 DQAIAGLNGMQLGDKKLLVQRAS 196 Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 45/106 (42%), Gaps = 2/106 (1%) Query: 10 EQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRV 69 + L ++ S V +S+ L++G L +++ + ++ + G + + + Sbjct: 93 QPLPGMSENPSVYVPGVVST--VVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNL 150 Query: 70 CRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 +D+ T S GYA+ + D +AI LN + + + + Sbjct: 151 VKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRAS 196 >2DH7-A nrPDB Length = 105 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Query: 24 AATGSESQSVENSSA-SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 ++GS Q + S+ ++VGDL P ++ + F+P G +S RV +D T S GY Sbjct: 1 GSSGSSGQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYG 60 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 +V+F + AI + + GR R W+ R P S Sbjct: 61 FVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPSGPSS 104 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKAITE 381 ++FV +L + E ++ FAP+G I+ A+V++ GKSKG+GFV F +A AI Sbjct: 17 HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH 76 Query: 382 KNQQIVAGKPLYVAIAQRK 400 Q + G+ + A RK Sbjct: 77 MGGQWLGGRQIRTNWATRK 95 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGF 263 S ++ +++ +++V +++ E T E + FA FG I A + KD A GK KG+GF Sbjct: 2 SSGSSGQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGF 61 Query: 264 VNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 V++ DA A+ + L G ++ A +K Sbjct: 62 VSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKP 96 Score = 89.4 bits (220), Expect = 4e-18, Method: Composition-based stats. Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query: 119 SLRKKGSGN---IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFE 174 S +KK + N +F+ +L P+I + + F+ FG I +++ D GKSKG+GFV F Sbjct: 6 SGQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFY 65 Query: 175 EEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 + A+ AI + G L G++I + Sbjct: 66 NKLDAENAIVHMGGQWLGGRQIRTNWATRKPP 97 >1D8Z-A nrPDB Length = 89 Score = 108 bits (269), Expect = 8e-24, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 2/90 (2%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 +S +L V L ++++ +F IG + S ++ RD IT SLGY +VN++D K Sbjct: 2 DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADK 61 Query: 95 AIEQLNYTPIKGRLCRIMWSQRDPSLRKKG 124 AI LN ++ + ++ +++ PS Sbjct: 62 AINTLNGLKLQTKTIKVSYAR--PSSASIR 89 Score = 98.3 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAV 273 TNL V + T ++F+ LF G I S L +D G+ G+GFVNY DA Sbjct: 1 MDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 60 Query: 274 KAVEALNDSELNGEKLYVGRAQKKNERM 301 KA+ LN +L + + V A+ + + Sbjct: 61 KAINTLNGLKLQTKTIKVSYARPSSASI 88 Score = 97.5 bits (241), Expect = 2e-20, Method: Composition-based stats. Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 NL V L ++ ++ + F G I S K++R + G+S G+GFV +S P +A KAI Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 381 EKNQQIVAGKPLYVAIAQR 399 N + K + V+ A+ Sbjct: 65 TLNGLKLQTKTIKVSYARP 83 Score = 92.1 bits (227), Expect = 6e-19, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEA 182 N+ + L ++ F GDI S K+ D+ G+S G+GFV++ + A +A Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 183 IDALNGMLLNGQEIYVAPHLSRKE 206 I+ LNG+ L + I V+ Sbjct: 63 INTLNGLKLQTKTIKVSYARPSSA 86 >2SXL-A nrPDB Length = 88 Score = 106 bits (264), Expect = 3e-23, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 46/80 (57%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 S+ +L V L +++ LY +F IG +++ R+ RD T S GYA+V+F ++A Sbjct: 2 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRA 61 Query: 96 IEQLNYTPIKGRLCRIMWSQ 115 I+ LN ++ + ++ +++ Sbjct: 62 IKVLNGITVRNKRLKVSYAR 81 Score = 98.3 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVK 274 A TNL V + + TD + LF GPI + + +D G G+ FV++ D+ + Sbjct: 1 ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQR 60 Query: 275 AVEALNDSELNGEKLYVGRAQKKNERMH 302 A++ LN + ++L V A+ E + Sbjct: 61 AIKVLNGITVRNKRLKVSYARPGGESIK 88 Score = 92.1 bits (227), Expect = 6e-19, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEA 182 + N+ + L D+ ++ LY F G I + +I D + G S G+ FV F E ++ A Sbjct: 2 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRA 61 Query: 183 IDALNGMLLNGQEIYVAPHLSRKE 206 I LNG+ + + + V+ E Sbjct: 62 IKVLNGITVRNKRLKVSYARPGGE 85 Score = 87.1 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKAI 379 NL V L + D +L F G I + ++MR + G S G+ FV F++ ++ +AI Sbjct: 3 NTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRAI 62 Query: 380 TEKNQQIVAGKPLYVAIAQR 399 N V K L V+ A+ Sbjct: 63 KVLNGITVRNKRLKVSYARP 82 >2CQB-A nrPDB Length = 102 Score = 105 bits (263), Expect = 4e-23, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 44/88 (50%) Query: 28 SESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFN 87 S S + + LYVG L V + L+ F P G ++ I++ D T+ G+A+V F Sbjct: 3 SGSSGMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFE 62 Query: 88 DHEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 E AI+ +N + + GR R+ ++ Sbjct: 63 LAEDAAAAIDNMNESELFGRTIRVNLAK 90 Score = 100 bits (250), Expect = 1e-21, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 15 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 74 Query: 383 NQQIVAGKPLYVAIAQRKDVRRS 405 N+ + G+ + V +A+ ++ S Sbjct: 75 NESELFGRTIRVNLAKPMRIKES 97 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 15 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 74 Query: 187 NGMLLNGQEIYVAPHLSRKERDSQ 210 N L G+ I V + ++S Sbjct: 75 NESELFGRTIRVNLAKPMRIKESG 98 Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 1/92 (1%) Query: 207 RDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVN 265 S LYV + E D+ F FG I + D K +GF FV Sbjct: 1 GSSGSSGMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVE 60 Query: 266 YEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 +E EDA A++ +N+SEL G + V A+ Sbjct: 61 FELAEDAAAAIDNMNESELFGRTIRVNLAKPM 92 >3MDF-A nrPDB Length = 85 Score = 105 bits (263), Expect = 4e-23, Method: Composition-based stats. Identities = 25/84 (29%), Positives = 43/84 (51%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 S+ + LYVG L V + L+ F P G ++ I++ D T+ G+A+V F E Sbjct: 2 SMATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAED 61 Query: 92 GRKAIEQLNYTPIKGRLCRIMWSQ 115 AI+ +N + + GR R+ ++ Sbjct: 62 AAAAIDNMNESELFGRTIRVNLAK 85 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 383 NQQIVAGKPLYVAIAQ 398 N+ + G+ + V +A+ Sbjct: 70 NESELFGRTIRVNLAK 85 Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 187 NGMLLNGQEIYVAPH 201 N L G+ I V Sbjct: 70 NESELFGRTIRVNLA 84 Score = 87.9 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 1/76 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D K +GF FV +E EDA A++ + Sbjct: 10 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 69 Query: 280 NDSELNGEKLYVGRAQ 295 N+SEL G + V A+ Sbjct: 70 NESELFGRTIRVNLAK 85 >5MQF-o nrPDB Length = 301 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 9/115 (7%) Query: 33 VENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAG 92 + + LYVG L V + L+ F P G ++ I++ D T+ G+A+V F E Sbjct: 1 MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDA 60 Query: 93 RKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFS 147 AI+ +N + + GR R+ ++ P K+GS P + FS Sbjct: 61 AAAIDNMNESELFGRTIRVNLAK--PMRIKEGSSR-------PVWSDDDWLKKFS 106 Score = 100 bits (249), Expect = 2e-21, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 383 NQQIVAGKPLYVAIAQRKDVRR 404 N+ + G+ + V +A+ ++ Sbjct: 68 NESELFGRTIRVNLAKPMRIKE 89 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 3/105 (2%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D K +GF FV +E EDA A++ + Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 280 NDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNL 324 N+SEL G + V A+ + + + K K+ G L Sbjct: 68 NESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLK--KFSGKTL 110 Score = 90.6 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 8 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 67 Query: 187 NGMLLNGQEIYVAPHLSRKERD 208 N L G+ I V + ++ Sbjct: 68 NESELFGRTIRVNLAKPMRIKE 89 >5ZWM-X nrPDB Length = 148 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 3/128 (2%) Query: 17 IQDDQKQAATGSESQSVEN---SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDA 73 I D + Q+ S QS N +A +Y+G+L ++E + +FS G + + RD Sbjct: 7 INDKELQSGILSPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDE 66 Query: 74 ITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNL 133 T S G+AY+ + D + A++ LN I GR +I + P + + L Sbjct: 67 NTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQKYYEAVKEEL 126 Query: 134 HPDIDNKA 141 DI +K Sbjct: 127 DRDIVSKN 134 Score = 89.4 bits (220), Expect = 4e-18, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 4/117 (3%) Query: 96 IEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSS 155 I+Q+N ++ + S K + I+I NL+ ++ + FS +G + Sbjct: 4 IQQINDKELQSGILSPHQSWH---NEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDV 60 Query: 156 KIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQL 211 ++ DE G+S+GF ++ +E++ + A+D LNG + G+ + + R +R Q Sbjct: 61 ILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQK 117 Score = 85.2 bits (209), Expect = 7e-17, Method: Composition-based stats. Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGF 263 S E K +Y+ N+N E T+ +F+++G V L +D G+ +GF + Sbjct: 18 SPHQSWHNEYK-DNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAY 76 Query: 264 VNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVN 323 + YE + AV+ LN ++ G L + + +R L+K YEA + E N Sbjct: 77 LKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRS--LQKYYEAVKEELDRDIVSKN 134 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 38/99 (38%), Gaps = 1/99 (1%) Query: 309 EAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFV 367 ++ +++ NL+ + + + F+ YG + R E G+S+GF ++ Sbjct: 18 SPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYL 77 Query: 368 CFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQ 406 + A+ N + G+ L + + R Q Sbjct: 78 KYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQ 116 >2KU7-A nrPDB Length = 140 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 40/81 (49%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 + LYVG L V + L+ F P G ++ I++ D T+ G+A+V F E Sbjct: 60 ATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAA 119 Query: 94 KAIEQLNYTPIKGRLCRIMWS 114 AI+ +N + + GR R+ + Sbjct: 120 AAIDNMNESELFGRTIRVNLA 140 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 1/75 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 L+V L + VDD+ L F P+G IT ++ + E K +GF FV F E+A AI Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 383 NQQIVAGKPLYVAIA 397 N+ + G+ + V +A Sbjct: 126 NESELFGRTIRVNLA 140 Score = 89.4 bits (220), Expect = 4e-18, Method: Composition-based stats. Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ L ++D+K L+ F FGDI +I D E K +GF FV FE A AID + Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 187 NGMLLNGQEIYVAPH 201 N L G+ I V Sbjct: 126 NESELFGRTIRVNLA 140 Score = 88.2 bits (217), Expect = 9e-18, Method: Composition-based stats. Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEAL 279 LYV + E D+ F FG I + D K +GF FV +E EDA A++ + Sbjct: 66 LYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNM 125 Query: 280 NDSELNGEKLYVGRA 294 N+SEL G + V A Sbjct: 126 NESELFGRTIRVNLA 140 >5SZW-A nrPDB Length = 101 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Query: 201 HLSRKERDSQLEETKAHY--TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGK 257 H+S D E+ + TNL V + T ++ + LF+ G + SA L +D G Sbjct: 2 HMSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGH 61 Query: 258 LKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 G+GFVNY +DA +A+ LN L + + V A+ Sbjct: 62 SLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPS 101 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 43/78 (55%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 22 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 81 Query: 98 QLNYTPIKGRLCRIMWSQ 115 LN ++ + ++ +++ Sbjct: 82 TLNGLRLQSKTIKVSYAR 99 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Query: 302 HVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGK 360 H+ + + NL V L ++ ++L F+ G + SAK++R + G Sbjct: 2 HMSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGH 61 Query: 361 SKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQR 399 S G+GFV + T ++A +AI N + K + V+ A+ Sbjct: 62 SLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARP 100 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 122 KKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAK 180 G N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ Sbjct: 18 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 77 Query: 181 EAIDALNGMLLNGQEIYVAPHLSR 204 AI+ LNG+ L + I V+ Sbjct: 78 RAINTLNGLRLQSKTIKVSYARPS 101 >4FXV-A nrPDB Length = 99 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Query: 17 IQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK 76 + D+ E+ + +L V L ++++ L +FS IG V S ++ RD + Sbjct: 1 MGSDKIHHHHHHENLYFQ--GTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAG 58 Query: 77 TSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 SLGY +VN+ + +AI LN ++ + ++ +++ Sbjct: 59 HSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYAR 97 Score = 98.3 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Query: 319 YQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATK 377 +QG NL V L ++ ++L F+ G + SAK++R + G S G+GFV + T ++A + Sbjct: 17 FQGTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76 Query: 378 AITEKNQQIVAGKPLYVAIAQR 399 AI N + K + V+ A+ Sbjct: 77 AINTLNGLRLQSKTIKVSYARP 98 Score = 96.3 bits (238), Expect = 3e-20, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Query: 217 HYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKA 275 TNL V + T ++ + LF+ G + SA L +D G G+GFVNY +DA +A Sbjct: 18 QGTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77 Query: 276 VEALNDSELNGEKLYVGRAQKK 297 + LN L + + V A+ Sbjct: 78 INTLNGLRLQSKTIKVSYARPS 99 Score = 90.6 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 1/80 (1%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ AI+ Sbjct: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79 Query: 185 ALNGMLLNGQEIYVAPHLSR 204 LNG+ L + I V+ Sbjct: 80 TLNGLRLQSKTIKVSYARPS 99 >6FF4-1 nrPDB Length = 322 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 8/123 (6%) Query: 94 KAIEQLNYTPIK-GRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDI 152 K I +LN ++ G ++ W K S IF+ L ++ + FS +G+I Sbjct: 8 KLINELNEREVQLGVADKVSWHSEY-----KDSAWIFLGGLPYELTEGDIICVFSQYGEI 62 Query: 153 LSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAP-HLSRKERDSQ 210 ++ + D+ GKSKGF F+ +E++ + A+D NG+ + G+ I V R +DS+ Sbjct: 63 VNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSE 122 Query: 211 LEE 213 + Sbjct: 123 EID 125 Score = 90.6 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 50/110 (45%) Query: 10 EQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRV 69 + + LN ++ Q A S SA +++G L ++E + +FS G + +I + Sbjct: 8 KLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINL 67 Query: 70 CRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPS 119 RD T S G+ ++ + D + A++ N IKGR R+ + Sbjct: 68 VRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRA 117 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEK 382 +F+ L + + + F+ YG I + ++R + GKSKGF F+C+ A+ Sbjct: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97 Query: 383 NQQIVAGKPLYV----AIAQRKDVRR-SQLAQQIQAR 414 N + G+ + V KD + +Q+Q + Sbjct: 98 NGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEK 134 >3HI9-A nrPDB Length = 84 Score = 101 bits (252), Expect = 7e-22, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 43/78 (55%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +L V L ++++ L +FS IG V S ++ RD + SLGY +VN+ + +AI Sbjct: 5 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 64 Query: 98 QLNYTPIKGRLCRIMWSQ 115 LN ++ + ++ +++ Sbjct: 65 TLNGLRLQSKTIKVSYAR 82 Score = 96.3 bits (238), Expect = 3e-20, Method: Composition-based stats. Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 TNL V + T ++ + LF+ G + SA L +D G G+GFVNY +DA +A+ Sbjct: 5 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 64 Query: 278 ALNDSELNGEKLYVGRAQKK 297 LN L + + V A+ Sbjct: 65 TLNGLRLQSKTIKVSYARPS 84 Score = 95.6 bits (236), Expect = 5e-20, Method: Composition-based stats. Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 NL V L ++ ++L F+ G + SAK++R + G S G+GFV + T ++A +AI Sbjct: 5 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 64 Query: 381 EKNQQIVAGKPLYVAIAQR 399 N + K + V+ A+ Sbjct: 65 TLNGLRLQSKTIKVSYARP 83 Score = 92.9 bits (229), Expect = 4e-19, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKE 181 G N+ + L ++ L FS G++ S+K+ D+ G S G+GFV++ A+ Sbjct: 2 PGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 61 Query: 182 AIDALNGMLLNGQEIYVAPHLSR 204 AI+ LNG+ L + I V+ Sbjct: 62 AINTLNGLRLQSKTIKVSYARPS 84 >6GD1-A nrPDB Length = 206 Score = 101 bits (251), Expect = 1e-21, Method: Composition-based stats. Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 1/96 (1%) Query: 309 EAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFV 367 E G +F+ NL D+ L + F P+G +T+ KV+R K KGFGFV Sbjct: 111 EFLDANLAGSAMGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFV 170 Query: 368 CFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVR 403 + EEA AI N + K L V+ K + Sbjct: 171 TMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 206 Score = 92.1 bits (227), Expect = 6e-19, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 39/79 (49%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 +++ +L E L+ +F P G+V++++V RD T G+ +V ++E AI Sbjct: 125 CIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIAS 184 Query: 99 LNYTPIKGRLCRIMWSQRD 117 LN + ++ ++ + Sbjct: 185 LNGYRLGDKILQVSFKTNK 203 Score = 88.6 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 67/176 (38%), Gaps = 22/176 (12%) Query: 134 HPDIDNKALYDTFSVF-GDILSSKIATDEN-GKSKGFG------FVHFEEEGAAKEAIDA 185 + L + + G + +K+ D+N G + +G + F+ A + A Sbjct: 44 PCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGA 103 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPI 245 L+ L E A +++ N+ + + ++F FG + Sbjct: 104 LSKGQLK-------------EFLDANLAGSAMGWCIFIYNLGQDADEGILWQMFGPFGAV 150 Query: 246 VSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 300 + + +D K KGFGFV +E+A A+ +LN L + L V K+ + Sbjct: 151 TNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 206 Score = 87.9 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 IFI NL D D L+ F FG + + K+ D K KGFGFV A AI +L Sbjct: 126 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 185 Query: 187 NGMLLNGQEIYVAPHLSRKER 207 NG L + + V+ ++ + Sbjct: 186 NGYRLGDKILQVSFKTNKSHK 206 >2MYF-A nrPDB Length = 89 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 48/87 (55%) Query: 29 ESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFND 88 S N++ L+VG ++ ++ E LYDIFS G + +I V + TK + G+A+V + + Sbjct: 2 SHMSDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVE 61 Query: 89 HEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 + + A+ +N + G+ + +S+ Sbjct: 62 VDDAKHALYNMNNFELNGKRIHVNYSK 88 Score = 85.2 bits (209), Expect = 7e-17, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDAD-GKLKGFGFVNYEKHEDAVKAVEAL 279 L+V I+ ++ ++F+ FG I + + + K +GF FV Y + +DA A+ + Sbjct: 13 LFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYNM 72 Query: 280 NDSELNGEKLYVGRAQK 296 N+ ELNG++++V ++ Sbjct: 73 NNFELNGKRIHVNYSKT 89 Score = 85.2 bits (209), Expect = 8e-17, Method: Composition-based stats. Identities = 28/77 (36%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ + ID K+LYD FS FGDI + ++ + K++GF FV + E AK A+ + Sbjct: 13 LFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYNM 72 Query: 187 NGMLLNGQEIYVAPHLS 203 N LNG+ I+V + Sbjct: 73 NNFELNGKRIHVNYSKT 89 Score = 75.5 bits (184), Expect = 5e-14, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEK 382 LFV +D+++D++ L + F+ +G I + +V + K++GF FV + ++A A+ Sbjct: 13 LFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVEVDDAKHALYNM 72 Query: 383 NQQIVAGKPLYVAIAQ 398 N + GK ++V ++ Sbjct: 73 NNFELNGKRIHVNYSK 88 >6QX9-R nrPDB Length = 480 Score = 99.0 bits (245), Expect = 4e-21, Method: Composition-based stats. Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEAT 376 +F +L + V+D+ L F+ + + AKV+R + GK+KG+GFV F P + Sbjct: 377 DADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYV 436 Query: 377 KAITEKNQQIVAGKPLYVAIAQRKD 401 +A+ E N + V +P+ + + KD Sbjct: 437 RAMREMNGKYVGSRPIKLRKSMWKD 461 Score = 96.7 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 51/109 (46%), Gaps = 1/109 (0%) Query: 198 VAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADG 256 + D L E A ++ ++ +E D+ F++F + A + +D G Sbjct: 360 IRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTG 419 Query: 257 KLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLK 305 K KG+GFV+++ D V+A+ +N + + + ++ K+ + V++ Sbjct: 420 KTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVR 468 Score = 90.2 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%) Query: 114 SQRDPSLRKKG--SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGF 170 S DPSL + IF +L ++++ L FS F L +K+ D+ GK+KG+GF Sbjct: 367 SWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGF 426 Query: 171 VHFEEEGAAKEAIDALNGMLLNGQEIYVAPHL 202 V F++ A+ +NG + + I + + Sbjct: 427 VSFKDPSDYVRAMREMNGKYVGSRPIKLRKSM 458 Score = 69.8 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 37/90 (41%) Query: 33 VENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAG 92 + ++ GDL V++ L FS S +V RD T + GY +V+F D Sbjct: 376 WDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDY 435 Query: 93 RKAIEQLNYTPIKGRLCRIMWSQRDPSLRK 122 +A+ ++N + R ++ S Sbjct: 436 VRAMREMNGKYVGSRPIKLRKSMWKDRNLD 465 >1P1T-A nrPDB Length = 104 Score = 98.3 bits (243), Expect = 8e-21, Method: Composition-based stats. Identities = 28/94 (29%), Positives = 45/94 (47%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 +V+ S S++VG++ +E L DIFS +G V S R+ D T GY + + D E Sbjct: 3 AVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQET 62 Query: 92 GRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGS 125 A+ LN GR R+ + + + + S Sbjct: 63 ALSAMRNLNGREFSGRALRVDNAASEKNKEELKS 96 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Query: 118 PSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEE 176 + ++F+ N+ + + L D FS G ++S ++ D E GK KG+GF ++++ Sbjct: 1 DPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQ 60 Query: 177 GAAKEAIDALNGMLLNGQEIYVAPHLSRKERDS 209 A A+ LNG +G+ + V S K ++ Sbjct: 61 ETALSAMRNLNGREFSGRALRVDNAASEKNKEE 93 Score = 92.1 bits (227), Expect = 6e-19, Method: Composition-based stats. Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAV 273 +++V NI E T+EQ +++F++ GP+VS L D GK KG+GF Y+ E A+ Sbjct: 5 DRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETAL 64 Query: 274 KAVEALNDSELNGEKLYVGRA--QKKNERMHVL 304 A+ LN E +G L V A +K E + L Sbjct: 65 SAMRNLNGREFSGRALRVDNAASEKNKEELKSL 97 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKAIT 380 ++FV N+ +E+L++ F+ G + S +++ E GK KG+GF + E A A+ Sbjct: 9 RSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMR 68 Query: 381 EKNQQIVAGKPLYVAIAQRKDVRR 404 N + +G+ L V A + + Sbjct: 69 NLNGREFSGRALRVDNAASEKNKE 92 >2ERR-A nrPDB Length = 109 Score = 96.7 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFV 264 E K+ L+V NI D +++F +FG I+ + + G KGFGFV Sbjct: 16 PRGSHMNTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFV 74 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 +E DA +A E L+ + + G K+ V A + Sbjct: 75 TFENSADADRAREKLHGTVVEGRKIEVNNATAR 107 Score = 94.8 bits (234), Expect = 9e-20, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Query: 313 LEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTP 372 + K Q L V N+ D L + F +G I +++ E G SKGFGFV F Sbjct: 21 MNTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENS 79 Query: 373 EEATKAITEKNQQIVAGKPLYVAIAQ 398 +A +A + + +V G+ + V A Sbjct: 80 ADADRAREKLHGTVVEGRKIEVNNAT 105 Score = 87.9 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 1/94 (1%) Query: 111 IMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGF 170 + + K + + N+ + L F FG IL +I +E G SKGFGF Sbjct: 15 VPRGSHMNTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGF 73 Query: 171 VHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSR 204 V FE A A + L+G ++ G++I V +R Sbjct: 74 VTFENSADADRAREKLHGTVVEGRKIEVNNATAR 107 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 + L+V ++ + L +F G + + + + + S G+ +V F + + Sbjct: 27 SQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNE--RGSKGFGFVTFENSADADR 84 Query: 95 AIEQLNYTPIKGRLCRIMWSQRD 117 A E+L+ T ++GR + + Sbjct: 85 AREKLHGTVVEGRKIEVNNATAR 107 >2YWK-A nrPDB Length = 95 Score = 95.9 bits (237), Expect = 4e-20, Method: Composition-based stats. Identities = 28/75 (37%), Positives = 39/75 (52%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAIT 380 +FV NL+ V +E L E F G +T + + GK K FGFVCF PE + AI Sbjct: 16 DRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIA 75 Query: 381 EKNQQIVAGKPLYVA 395 N + G+P+ V+ Sbjct: 76 LLNGIRLYGRPINVS 90 Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 42/92 (45%) Query: 112 MWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFV 171 S +++ +F+ NL + + LY+ F G + I D GK K FGFV Sbjct: 3 SGSSGMFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFV 62 Query: 172 HFEEEGAAKEAIDALNGMLLNGQEIYVAPHLS 203 F+ + AI LNG+ L G+ I V+ S Sbjct: 63 CFKHPESVSYAIALLNGIRLYGRPINVSGPSS 94 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 39/90 (43%) Query: 203 SRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFG 262 + ++V N+ + +E ELF + GP+ ++ KD +GK K FG Sbjct: 1 GSSGSSGMFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFG 60 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVG 292 FV ++ E A+ LN L G + V Sbjct: 61 FVCFKHPESVSYAIALLNGIRLYGRPINVS 90 Score = 75.5 bits (184), Expect = 6e-14, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Query: 24 AATGSESQS--VENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGY 81 ++GS E + +++VG+LE V E LY++F G ++ + +C+D + Sbjct: 1 GSSGSSGMFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDRE-GKPKSF 59 Query: 82 AYVNFNDHEAGRKAIEQLNYTPIKGRLCRIM 112 +V F E+ AI LN + GR + Sbjct: 60 GFVCFKHPESVSYAIALLNGIRLYGRPINVS 90 >2DO0-A nrPDB Length = 114 Score = 95.2 bits (235), Expect = 7e-20, Method: Composition-based stats. Identities = 29/79 (36%), Positives = 48/79 (60%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAIT 380 G +FV NLD V +KL+E F+ G + A ++ ++GKS+G G V F EA +AI+ Sbjct: 15 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAIS 74 Query: 381 EKNQQIVAGKPLYVAIAQR 399 N Q++ +P++V + +R Sbjct: 75 MFNGQLLFDRPMHVKMDER 93 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 26/75 (34%), Positives = 42/75 (56%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDA 185 +F+ NL + K L + FS+ G ++ + I D++GKS+G G V FE+ A +AI Sbjct: 16 STVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISM 75 Query: 186 LNGMLLNGQEIYVAP 200 NG LL + ++V Sbjct: 76 FNGQLLFDRPMHVKM 90 Score = 83.6 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 49/108 (45%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFV 264 S + + ++V N++ + ++ +E+F+ G +V A + +D DGK +G G V Sbjct: 2 SSGSSGALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTV 61 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYR 312 +E+ +AV+A+ N L ++V ++ + + Sbjct: 62 TFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQS 109 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 35/93 (37%), Gaps = 1/93 (1%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAY 83 ++ S + ++++V +L+ V L ++FS G V + D S G Sbjct: 2 SSGSSGALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGT 60 Query: 84 VNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQR 116 V F +AI N + R + +R Sbjct: 61 VTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 93 >1D9A-A nrPDB Length = 85 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAI 379 NL+V L ++ +++E+ F+ YG I +++++ + G S+G GF+ F EA +AI Sbjct: 1 DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAI 60 Query: 380 TEKNQQIVAG--KPLYVAIAQR 399 N Q G +P+ V A Sbjct: 61 KGLNGQKPLGAAEPITVKFANN 82 Score = 84.8 bits (208), Expect = 9e-17, Method: Composition-based stats. Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAI 183 N+++ L + K + FS +G I++S+I D+ G S+G GF+ F++ A+EAI Sbjct: 1 DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAI 60 Query: 184 DALNGMLLNGQEIYVAPHLSRKE 206 LNG G + + Sbjct: 61 KGLNGQKPLGAAEPITVKFANNP 83 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 48/83 (57%), Gaps = 3/83 (3%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKGFGFVNYEKHEDAVKAVEA 278 NLYV + + ++ ++LF+++G I+++ + D A G +G GF+ ++K +A +A++ Sbjct: 3 NLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKG 62 Query: 279 LNDSELNG--EKLYVGRAQKKNE 299 LN + G E + V A ++ Sbjct: 63 LNGQKPLGAAEPITVKFANNPSQ 85 Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 37/85 (43%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 A+LYV L ++S+ + +FS G + + R+ D T S G ++ F+ +AI Sbjct: 1 DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAI 60 Query: 97 EQLNYTPIKGRLCRIMWSQRDPSLR 121 + LN G I + + Sbjct: 61 KGLNGQKPLGAAEPITVKFANNPSQ 85 >1SXL-A nrPDB Length = 97 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 3/84 (3%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEAT 376 + NL+V NL ++ D++L+ F YG+I ++R + G+ +G FV ++ EEA Sbjct: 10 SIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQ 69 Query: 377 KAITEKNQQIVAG--KPLYVAIAQ 398 +AI+ N I G +PL V +A+ Sbjct: 70 EAISALNNVIPEGGSQPLSVRLAE 93 Score = 90.6 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 114 SQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVH 172 S P N+++ NL I + L F +G I+ I D+ G+ +G FV Sbjct: 2 SYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVR 61 Query: 173 FEEEGAAKEAIDALNGMLLNG--QEIYVAPH 201 + + A+EAI ALN ++ G Q + V Sbjct: 62 YNKREEAQEAISALNNVIPEGGSQPLSVRLA 92 Score = 82.1 bits (201), Expect = 7e-16, Method: Composition-based stats. Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 3/89 (3%) Query: 214 TKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDA 272 TNLYV N+ TD+Q +F K+G IV ++ +D G+ +G FV Y K E+A Sbjct: 9 ESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEA 68 Query: 273 VKAVEALNDSELNG--EKLYVGRAQKKNE 299 +A+ ALN+ G + L V A++ + Sbjct: 69 QEAISALNNVIPEGGSQPLSVRLAEEHGK 97 Score = 81.7 bits (200), Expect = 9e-16, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 39/86 (45%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 +LYV +L ++++ L IF GS+ + RD +T G A+V +N E ++A Sbjct: 12 KDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEA 71 Query: 96 IEQLNYTPIKGRLCRIMWSQRDPSLR 121 I LN +G + + + Sbjct: 72 ISALNNVIPEGGSQPLSVRLAEEHGK 97 >2DH9-A nrPDB Length = 89 Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKN 383 +FV+NL + L+++F G + A + + ENGKSKG G V F +PE A +A N Sbjct: 8 IFVRNLPFDFTWKMLKDKFNECGHVLYADI-KMENGKSKGCGVVKFESPEVAERACRMMN 66 Query: 384 QQIVAGKPLYVAIAQR 399 ++G+ + V I + Sbjct: 67 GMKLSGREIDVRIDRN 82 Score = 92.9 bits (229), Expect = 3e-19, Method: Composition-based stats. Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Query: 122 KKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKE 181 GS IF++NL D K L D F+ G +L + I ENGKSKG G V FE A+ Sbjct: 2 SSGSSGIFVRNLPFDFTWKMLKDKFNECGHVLYADIKM-ENGKSKGCGVVKFESPEVAER 60 Query: 182 AIDALNGMLLNGQEIYVAPHLSRKERDSQ 210 A +NGM L+G+EI V + S Sbjct: 61 ACRMMNGMKLSGREIDVRIDRNASGPSSG 89 Score = 69.8 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 + + ++V+N+ + T + ++ F + G ++ A + K +GK KG G V +E E A + Sbjct: 2 SSGSSGIFVRNLPFDFTWKMLKDKFNECGHVLYADI-KMENGKSKGCGVVKFESPEVAER 60 Query: 275 AVEALNDSELNGEKLYVG 292 A +N +L+G ++ V Sbjct: 61 ACRMMNGMKLSGREIDVR 78 Score = 59.0 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 8/85 (9%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSV--SSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 ++V +L + L D F+ G V + I++ S G V F E +A Sbjct: 8 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKM----ENGKSKGCGVVKFESPEVAERACR 63 Query: 98 QLNYTPIKGRLC--RIMWSQRDPSL 120 +N + GR RI + PS Sbjct: 64 MMNGMKLSGREIDVRIDRNASGPSS 88 >1NMR-A nrPDB Length = 85 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 2/73 (2%) Query: 494 ANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFE 553 + ++Q+ LGE+LY + A N AA K+TGM+L++ E+ LL++ L + Sbjct: 12 STVLANLTPEQQKNVLGERLYNHIVAI--NPAAAAKVTGMLLEMDNGEILNLLDTPGLLD 69 Query: 554 QHYKEASAAYESF 566 +EA Sbjct: 70 AKVQEALEVLNRH 82 >4ZKA-A nrPDB Length = 100 Score = 92.5 bits (228), Expect = 4e-19, Method: Composition-based stats. Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Query: 211 LEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHE 270 E K+ L+V NI D +++F +FG I+ + + G KGFGFV +E Sbjct: 1 NTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSA 59 Query: 271 DAVKAVEALNDSELNGEKLYVGRAQKK 297 DA +A E L+ + + G K+ V A + Sbjct: 60 DADRAREKLHGTVVEGRKIEVNNATAR 86 Score = 92.5 bits (228), Expect = 5e-19, Method: Composition-based stats. Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 314 EKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPE 373 K Q L V N+ D L + F +G I +++ E G SKGFGFV F Sbjct: 1 NTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSA 59 Query: 374 EATKAITEKNQQIVAGKPLYVAIAQ 398 +A +A + + +V G+ + V A Sbjct: 60 DADRAREKLHGTVVEGRKIEVNNAT 84 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 1/78 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 + + N+ + L F FG IL +I +E G SKGFGFV FE A A + L Sbjct: 10 RLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRAREKL 68 Query: 187 NGMLLNGQEIYVAPHLSR 204 +G ++ G++I V +R Sbjct: 69 HGTVVEGRKIEVNNATAR 86 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRK 94 + L+V ++ + L +F G + + + + + S G+ +V F + + Sbjct: 6 SQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNE--RGSKGFGFVTFENSADADR 63 Query: 95 AIEQLNYTPIKGRLCRIMWSQRD 117 A E+L+ T ++GR + + Sbjct: 64 AREKLHGTVVEGRKIEVNNATAR 86 >2CQ3-A nrPDB Length = 103 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAIT 380 L V N+ D L + F +G I +++ E G SKGFGFV F +A +A Sbjct: 15 PKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRARE 73 Query: 381 EKNQQIVAGKPLYVAIAQ 398 + + +V G+ + V A Sbjct: 74 KLHGTVVEGRKIEVNNAT 91 Score = 90.2 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVE 277 L+V NI D +++F +FG I+ + + G KGFGFV +E DA +A E Sbjct: 15 PKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRARE 73 Query: 278 ALNDSELNGEKLYVGRAQKK 297 L+ + + G K+ V A + Sbjct: 74 KLHGTVVEGRKIEVNNATAR 93 Score = 88.2 bits (217), Expect = 9e-18, Method: Composition-based stats. Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 + + N+ + L F FG IL +I +E G SKGFGFV FE A A + L Sbjct: 17 RLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERG-SKGFGFVTFENSADADRAREKL 75 Query: 187 NGMLLNGQEIYVAPHLSRKERDSQ 210 +G ++ G++I V +R +S Sbjct: 76 HGTVVEGRKIEVNNATARVMTNSG 99 Score = 69.0 bits (167), Expect = 6e-12, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 + L+V ++ + L +F G + + + + + S G+ +V F + +A Sbjct: 14 TPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNE--RGSKGFGFVTFENSADADRA 71 Query: 96 IEQLNYTPIKGRLCRIMWSQRD 117 E+L+ T ++GR + + Sbjct: 72 REKLHGTVVEGRKIEVNNATAR 93 >1X5O-A nrPDB Length = 114 Score = 90.2 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 45/95 (47%) Query: 297 KNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT 356 + LK ++ K + NL++ NL S+D+++LE P+G + S +++R Sbjct: 1 GSSGSSGLKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRD 60 Query: 357 ENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKP 391 +G S+G GF + E+ I N + + P Sbjct: 61 SSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 95 Score = 84.4 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 38/83 (45%) Query: 121 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 +++ N++I NL +D + L + FG ++S++I D +G S+G GF E + Sbjct: 21 QEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCE 80 Query: 181 EAIDALNGMLLNGQEIYVAPHLS 203 I NG + AP Sbjct: 81 AVIGHFNGKFIKTPPGVSAPTEP 103 Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 36/82 (43%) Query: 203 SRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFG 262 + + ++ + TNLY+ N+ +++ + + FG ++S + +D+ G +G G Sbjct: 10 ASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVG 69 Query: 263 FVNYEKHEDAVKAVEALNDSEL 284 F E E + N + Sbjct: 70 FARMESTEKCEAVIGHFNGKFI 91 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 E +LY+ +L S+ E L ++ P G V S R+ RD + TS G + E Sbjct: 22 EQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCE 80 Query: 94 KAIEQLNYTPIK 105 I N IK Sbjct: 81 AVIGHFNGKFIK 92 >1P27-B nrPDB Length = 106 Score = 89.8 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 204 RKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFG 262 ++ D + L+V ++ E T+E + FA++G I + L D G LKG+ Sbjct: 9 EQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYT 68 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 V YE +++A A+E LN +L G+ + V + Sbjct: 69 LVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRG 104 Score = 75.9 bits (185), Expect = 4e-14, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 86 NGQDLMGQPISVDW 99 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Query: 307 QYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFG 365 + + +G LFV + + +E + ++FA YG I + + + G KG+ Sbjct: 9 EQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYT 68 Query: 366 FVCFSTPEEATKAITEKNQQIVAGKPLYVAI 396 V + T +EA A+ N Q + G+P+ V Sbjct: 69 LVEYETYKEAQAAMEGLNGQDLMGQPISVDW 99 Score = 69.8 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 187 NGMLLNGQEIYVA 199 NG L GQ I V Sbjct: 86 NGQDLMGQPISVD 98 >3EX7-B nrPDB Length = 126 Score = 89.8 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 204 RKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFG 262 ++ D + L+V ++ E T+E + FA++G I + L D G LKG+ Sbjct: 8 EQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYT 67 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQ 295 V YE +++A A+E LN +L G+ + V Sbjct: 68 LVEYETYKEAQAAMEGLNGQDLMGQPISVDWCF 100 Score = 76.7 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 85 NGQDLMGQPISVDW 98 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Query: 307 QYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFG 365 + + +G LFV + + +E + ++FA YG I + + + G KG+ Sbjct: 8 EQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYT 67 Query: 366 FVCFSTPEEATKAITEKNQQIVAGKPLYVAI 396 V + T +EA A+ N Q + G+P+ V Sbjct: 68 LVEYETYKEAQAAMEGLNGQDLMGQPISVDW 98 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 187 NGMLLNGQEIYVA 199 NG L GQ I V Sbjct: 85 NGQDLMGQPISVD 97 >2HYI-B nrPDB Length = 91 Score = 89.4 bits (220), Expect = 4e-18, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Query: 212 EETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHE 270 + L+V ++ E T+E + FA++G I + L D G LKG+ V YE ++ Sbjct: 3 PQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYK 62 Query: 271 DAVKAVEALNDSELNGEKLYVGRAQKKN 298 +A A+E LN +L G+ + V + Sbjct: 63 EAQAAMEGLNGQDLMGQPISVDWCFVRG 90 Score = 76.7 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 35/76 (46%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 100 NYTPIKGRLCRIMWSQ 115 N + G+ + W Sbjct: 72 NGQDLMGQPISVDWCF 87 Score = 74.4 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPE 373 +G LFV + + +E + ++FA YG I + + + G KG+ V + T + Sbjct: 3 PQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYK 62 Query: 374 EATKAITEKNQQIVAGKPLYVAI 396 EA A+ N Q + G+P+ V Sbjct: 63 EAQAAMEGLNGQDLMGQPISVDW 85 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 187 NGMLLNGQEIYVA 199 NG L GQ I V Sbjct: 72 NGQDLMGQPISVD 84 >6C8U-1 nrPDB Length = 115 Score = 89.4 bits (220), Expect = 4e-18, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 1/93 (1%) Query: 27 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNF 86 G+E+ ++++ +++G L S L D FS G + V RD TK S G+ +V F Sbjct: 14 GTENLYFQSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 73 Query: 87 NDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPS 119 D + K + Q ++ + + + + Sbjct: 74 ADPASVDKVLGQPHH-ELDSKTIDPKVAFPRRA 105 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 2/96 (2%) Query: 122 KKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGK-SKGFGFVHFEEEGAAK 180 + +G +FI L +L D FS FG+I + D K S+GFGFV F + + Sbjct: 21 QSNAGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVD 80 Query: 181 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKA 216 + + + L+ + I R+ + + TK Sbjct: 81 KVLGQPH-HELDSKTIDPKVAFPRRAQPKMVTRTKK 115 Score = 72.1 bits (175), Expect = 6e-13, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK-SKGFGFVCFSTPEEATKAITE 381 +F+ L + L + F+ +G I VMR K S+GFGFV F+ P K + + Sbjct: 26 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 85 Query: 382 KNQQIVAGKPLYVAIAQRKDVR 403 + + K + +A + + Sbjct: 86 PHH-ELDSKTIDPKVAFPRRAQ 106 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGK-LKGFGFVNYEKHEDAVKAVEA 278 +++ ++ +T+ + ++ F+KFG I + +D K +GFGFV + K + Sbjct: 26 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 85 Query: 279 LNDSELNGEKLYVGRAQKK 297 + EL+ + + A + Sbjct: 86 PH-HELDSKTIDPKVAFPR 103 >5YZG-w nrPDB Length = 174 Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 204 RKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFG 262 ++ D + L+V ++ E T+E + FA++G I + L D G LKG+ Sbjct: 58 EQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYT 117 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQ 295 V YE +++A A+E LN +L G+ + V Sbjct: 118 LVEYETYKEAQAAMEGLNGQDLMGQPISVDWCF 150 Score = 75.9 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 100 NYTPIKGRLCRIMW 113 N + G+ + W Sbjct: 135 NGQDLMGQPISVDW 148 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Query: 307 QYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFG 365 + + +G LFV + + +E + ++FA YG I + + + G KG+ Sbjct: 58 EQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYT 117 Query: 366 FVCFSTPEEATKAITEKNQQIVAGKPLYVAI 396 V + T +EA A+ N Q + G+P+ V Sbjct: 118 LVEYETYKEAQAAMEGLNGQDLMGQPISVDW 148 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 187 NGMLLNGQEIYVA 199 NG L GQ I V Sbjct: 135 NGQDLMGQPISVD 147 >2XS2-A nrPDB Length = 102 Score = 88.6 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEE 374 K +FV +D +D+ ++ FA YG++ K++ G SKG+GFV F + Sbjct: 3 PEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVD 62 Query: 375 ATKAITEKNQQIVAGKPLYVAIAQRK 400 K + Q GK L + A RK Sbjct: 63 VQKIVES--QINFHGKKLKLGPAIRK 86 Score = 83.2 bits (204), Expect = 3e-16, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 210 QLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKH 269 L E K ++V I+ + + + FA++G + + D G KG+GFV++ Sbjct: 1 SLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYND 60 Query: 270 EDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVL 304 D K VE+ +G+KL +G A +K Sbjct: 61 VDVQKIVES--QINFHGKKLKLGPAIRKQNLSTYH 93 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 42/80 (52%), Gaps = 2/80 (2%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ + +D + F+ +G + KI TD G SKG+GFV F + ++ +++ Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQ 70 Query: 187 NGMLLNGQEIYVAPHLSRKE 206 + +G+++ + P + ++ Sbjct: 71 --INFHGKKLKLGPAIRKQN 88 Score = 65.5 bits (158), Expect = 6e-11, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 +++VG ++ + E + F+ GSV +++ D T S GY +V+F + +K + Sbjct: 9 PNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIV 67 Query: 97 EQLNYTPIKGRLCRIMWSQRDPSLRKK 123 E G+ ++ + R +L Sbjct: 68 ESQ--INFHGKKLKLGPAIRKQNLSTY 92 >2J0Q-D nrPDB Length = 109 Score = 88.6 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Query: 212 EETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHE 270 + L+V ++ E T+E + FA++G I + L D G LKG+ V YE ++ Sbjct: 1 PQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYK 60 Query: 271 DAVKAVEALNDSELNGEKLYVGRAQ 295 +A A+E LN +L G+ + V Sbjct: 61 EAQAAMEGLNGQDLMGQPISVDWCF 85 Score = 76.7 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 35/76 (46%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L+V + +E ++D F+ G + +I + D T GY V + ++ + A+E L Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 100 NYTPIKGRLCRIMWSQ 115 N + G+ + W Sbjct: 70 NGQDLMGQPISVDWCF 85 Score = 74.4 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPE 373 +G LFV + + +E + ++FA YG I + + + G KG+ V + T + Sbjct: 1 PQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYK 60 Query: 374 EATKAITEKNQQIVAGKPLYVAI 396 EA A+ N Q + G+P+ V Sbjct: 61 EAQAAMEGLNGQDLMGQPISVDW 83 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ +H + + ++D F+ +G+I + + D G KG+ V +E A+ A++ L Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 187 NGMLLNGQEIYVA 199 NG L GQ I V Sbjct: 70 NGQDLMGQPISVD 82 >4PKD-B nrPDB Length = 279 Score = 88.6 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 41/239 (17%), Positives = 83/239 (34%), Gaps = 66/239 (27%) Query: 125 SGNIFIKNLHPDIDNKAL----YDTFSVFGDILSSKIATDENGKSKGF------------ 168 + I+I NL+ I L Y FS FG IL ++ + + F Sbjct: 8 NHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNA 67 Query: 169 -----GFVHFEEEGAAKEA------IDALNGMLLN------------------------- 192 GF +++ + A I + G + Sbjct: 68 LRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRGSGSGSGSGSGSGAETR 127 Query: 193 ----GQEIYVAPHLSRKERDSQLEETKAH---------YTNLYVKNINSETTDEQFQELF 239 ++ ++E +++L+ H + L+V +N +TT+ + + F Sbjct: 128 EERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREF 187 Query: 240 AKFGPIVSASLEK-DADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 +GPI + GK +G+ F+ YE D A + + +++G ++ V + + Sbjct: 188 EVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGR 246 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 37/242 (15%), Positives = 87/242 (35%), Gaps = 60/242 (24%) Query: 220 NLYVKNINSETTDEQF----QELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKA 275 +Y+ N+N + ++ +F++FG I+ + + K++G FV +++ A A Sbjct: 10 TIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSR--SLKMRGQAFVIFKEVSSATNA 67 Query: 276 VEALNDSELNGEKLYVGRAQKKNERMHVLKK----------------------------- 306 + ++ + + + A+ ++ + +K Sbjct: 68 LRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRGSGSGSGSGSGSGAETR 127 Query: 307 ---------------QYEAYRLEKMAKYQG---------VNLFVKNLDDSVDDEKLEEEF 342 Q E KM LFV ++ + KL EF Sbjct: 128 EERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREF 187 Query: 343 APYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKD 401 YG I ++ ++ +GK +G+ F+ + + A + + + G+ + V + + + Sbjct: 188 EVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRT 247 Query: 402 VR 403 V+ Sbjct: 248 VK 249 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 29/79 (36%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 +L+V + +E+ L F G + I + + GYA++ + A + Sbjct: 168 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 227 Query: 99 LNYTPIKGRLCRIMWSQRD 117 + I GR + + Sbjct: 228 ADGKKIDGRRVLVDVERGR 246 >1OO0-B nrPDB Length = 110 Score = 88.6 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Query: 204 RKERDSQLE---ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLK 259 R E D +LE + L+V +I+ E +++ QE F +G I + L D G K Sbjct: 9 RNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSK 68 Query: 260 GFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 G+ V YE H+ A+ A EALN +E+ G+ + V K Sbjct: 69 GYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKG 107 Score = 76.3 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 5/98 (5%) Query: 16 NIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAIT 75 N DD+ + + L+V + E + + F G + +I + D T Sbjct: 10 NEDDDELEPGPQRSVEGW-----ILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRT 64 Query: 76 KTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMW 113 S GYA V + H+ A E LN I G+ ++ W Sbjct: 65 GFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDW 102 Score = 66.7 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 1/91 (1%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPE 373 +G LFV ++ + +++++E+F YG I + + + G SKG+ V + T + Sbjct: 20 PQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHK 79 Query: 374 EATKAITEKNQQIVAGKPLYVAIAQRKDVRR 404 +A A N + G+ + V K +R Sbjct: 80 QALAAKEALNGAEIMGQTIQVDWCFVKGPKR 110 Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ ++H + + + F +G+I + + D G SKG+ V +E A A +AL Sbjct: 29 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 88 Query: 187 NGMLLNGQEIYVAPHLSRKER 207 NG + GQ I V + + Sbjct: 89 NGAEIMGQTIQVDWCFVKGPK 109 >2XS5-A nrPDB Length = 87 Score = 88.2 bits (217), Expect = 9e-18, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEE 374 K +FV +D +D+ ++ FA YG++ K++ G SKG+GFV F + Sbjct: 3 PEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVD 62 Query: 375 ATKAITEKNQQIVAGKPLYVAIAQRK 400 K + Q GK L + A RK Sbjct: 63 VQKIVES--QINFHGKKLKLGPAIRK 86 Score = 82.8 bits (203), Expect = 4e-16, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Query: 210 QLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKH 269 L E K ++V I+ + + + FA++G + + D G KG+GFV++ Sbjct: 1 SLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYND 60 Query: 270 EDAVKAVEALNDSELNGEKLYVGRAQKK 297 D K VE+ +G+KL +G A +K Sbjct: 61 VDVQKIVES--QINFHGKKLKLGPAIRK 86 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ + +D + F+ +G + KI TD G SKG+GFV F + ++ +++ Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQ 70 Query: 187 NGMLLNGQEIYVAPHLSRK 205 + +G+++ + P + ++ Sbjct: 71 --INFHGKKLKLGPAIRKQ 87 Score = 65.1 bits (157), Expect = 9e-11, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 +++VG ++ + E + F+ GSV +++ D T S GY +V+F + +K + Sbjct: 9 PNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDR-TGVSKGYGFVSFYNDVDVQKIV 67 Query: 97 EQLNYTPIKGRLCRIMWSQRD 117 E G+ ++ + R Sbjct: 68 ESQ--INFHGKKLKLGPAIRK 86 >1RK8-A nrPDB Length = 165 Score = 86.7 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 40/142 (28%), Positives = 61/142 (42%), Gaps = 15/142 (10%) Query: 172 HFEEEGAAKEAIDALN-----------GMLLNGQEIYVAPHLSRKERDSQLE---ETKAH 217 FE + + I L G N +E + R E D +LE + Sbjct: 12 EFEVDEDGDQGIVRLKEKAKHRKGRGFGSDSNTREAIHSYERVRNEDDDELEPGPQRSVE 71 Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAV 276 L+V +I+ E +++ QE F +G I + L D G KG+ V YE H+ A+ A Sbjct: 72 GWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAK 131 Query: 277 EALNDSELNGEKLYVGRAQKKN 298 EALN +E+ G+ + V K Sbjct: 132 EALNGAEIMGQTIQVDWCFVKG 153 Score = 76.3 bits (186), Expect = 4e-14, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 5/112 (4%) Query: 16 NIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAIT 75 N DD+ + + L+V + E + + F G + +I + D T Sbjct: 56 NEDDDELEPGPQRSVEGW-----ILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRT 110 Query: 76 KTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGN 127 S GYA V + H+ A E LN I G+ ++ W R K S Sbjct: 111 GFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSEK 162 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 63/150 (42%), Gaps = 8/150 (5%) Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLE----KMAKYQ 320 +E ED + + L + + + G E +H ++ E + Sbjct: 12 EFEVDEDGDQGIVRLKEKAKHRKGRGFGSDSNTREAIHSYERVRNEDDDELEPGPQRSVE 71 Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAI 379 G LFV ++ + +++++E+F YG I + + + G SKG+ V + T ++A A Sbjct: 72 GWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAK 131 Query: 380 TEKNQQIVAGKPLYVAIAQ---RKDVRRSQ 406 N + G+ + V K V++S+ Sbjct: 132 EALNGAEIMGQTIQVDWCFVKGPKRVKKSE 161 Score = 64.4 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDAL 186 +F+ ++H + + + F +G+I + + D G SKG+ V +E A A +AL Sbjct: 75 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 134 Query: 187 NGMLLNGQEIYVAPHLSRKERDSQLEETKA 216 NG + GQ I V + + + E + Sbjct: 135 NGAEIMGQTIQVDWCFVKGPKRVKKSEKRR 164 >2MGZ-B nrPDB Length = 105 Score = 85.9 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 IF+ L +K L++ F FGDI + + TD KS+G+GFV ++ +A+ A Sbjct: 17 TKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACK 76 Query: 185 ALNGMLLNGQEIYVAPHL 202 N +++G++ V Sbjct: 77 DPNP-IIDGRKANVNLAY 93 Score = 78.2 bits (191), Expect = 8e-15, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 1/83 (1%) Query: 32 SVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 S + ++VG L S+ L++ F G + V D T+ S GY +V D + Sbjct: 11 SRDTMFTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRAS 70 Query: 92 GRKAIEQLNYTPIKGRLCRIMWS 114 +A + N I GR + + Sbjct: 71 AERACKDPN-PIIDGRKANVNLA 92 Score = 77.5 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 203 SRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGF 261 + + +T ++V + T+D+ E F +FG I A + D K +G+ Sbjct: 1 GSTNAEPVVGSRDTMFTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGY 60 Query: 262 GFVNYEKHEDAVKAVEALNDSELNGEKLYVGRA 294 GFV + A +A + N ++G K V A Sbjct: 61 GFVTMKDRASAERACKDPNPI-IDGRKANVNLA 92 Score = 75.9 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 +FV L D+ L E F +G I A V+ KS+G+GFV A +A Sbjct: 17 TKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACK 76 Query: 381 EKNQQIVAGKPLYVAIA 397 + N I+ G+ V +A Sbjct: 77 DPN-PIIDGRKANVNLA 92 >3NNH-A nrPDB Length = 88 Score = 85.2 bits (209), Expect = 8e-17, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 3/84 (3%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK--TSLGYAYVNFNDHEAGRKAI 96 ++VG + + SE L ++F G+V I V RD S G +V F +A +A Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 97 EQL-NYTPIKGRLCRIMWSQRDPS 119 L N + G I D Sbjct: 65 NALHNMKVLPGMHHPIQMKPADSE 88 Score = 84.8 bits (208), Expect = 1e-16, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 4/87 (4%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENG---KSKGFGFVHFEEEGAAK 180 + +F+ + K L + F +G + + D + +SKG FV F AA Sbjct: 2 DAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAAL 61 Query: 181 EAIDALNGM-LLNGQEIYVAPHLSRKE 206 EA +AL+ M +L G + + E Sbjct: 62 EAQNALHNMKVLPGMHHPIQMKPADSE 88 Score = 72.8 bits (177), Expect = 4e-13, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG---KLKGFGFVNYEKHEDA 272 + ++V + +++ +ELF ++G + ++ +D + KG FV + + A Sbjct: 1 SDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAA 60 Query: 273 VKAVEALNDSEL 284 ++A AL++ ++ Sbjct: 61 LEAQNALHNMKV 72 Score = 61.7 bits (148), Expect = 8e-10, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 6/81 (7%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENG---KSKGFGFVCFSTPEEATKAI 379 +FV + + ++ L E F YG + V+R + +SKG FV F T + A +A Sbjct: 5 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 380 TEKNQQIV---AGKPLYVAIA 397 + V P+ + A Sbjct: 65 NALHNMKVLPGMHHPIQMKPA 85 >2RS2-A nrPDB Length = 109 Score = 84.8 bits (208), Expect = 1e-16, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 36/90 (40%), Gaps = 1/90 (1%) Query: 30 SQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDH 89 + +S +++G L ++ L + F G V V RD +TK S G+ +V F D Sbjct: 18 GSHMGSSGCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQ 77 Query: 90 EAGRKAIEQLNYTPIKGRLCRIMWSQRDPS 119 K + Q + + + + + Sbjct: 78 AGVDKVLAQSRH-ELDSKTIDPKVAFPRRA 106 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 +FI L + L + F FG++ + D +S+GFGFV F ++ + + Sbjct: 26 CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL- 84 Query: 185 ALNGMLLNGQEIYVAPHLSRKER 207 A + L+ + I R+ + Sbjct: 85 AQSRHELDSKTIDPKVAFPRRAQ 107 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVK 274 + +++ ++ +TT E +E F +FG + + +D + +GFGFV + K Sbjct: 23 SSGCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDK 82 Query: 275 AVEALNDSELNGEKLYVGRAQKK 297 + EL+ + + A + Sbjct: 83 VLAQSR-HELDSKTIDPKVAFPR 104 Score = 68.2 bits (165), Expect = 8e-12, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAI 379 G +F+ L E L E F +G + VMR +S+GFGFV F K + Sbjct: 25 GCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL 84 Query: 380 TEKNQQIVAGKPLYVAIAQRKDVR 403 + ++ + K + +A + + Sbjct: 85 AQ-SRHELDSKTIDPKVAFPRRAQ 107 >2LEC-A nrPDB Length = 135 Score = 82.8 bits (203), Expect = 4e-16, Method: Composition-based stats. Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 1/100 (1%) Query: 114 SQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVH 172 S P +G ++ + NL L F +G + I D +S+GF FV Sbjct: 36 SYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVR 95 Query: 173 FEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLE 212 F ++ A++A+DA++G +L+G+E+ V + DS Sbjct: 96 FHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHS 135 Score = 79.8 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 38/78 (48%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 SL V +L S L +F G V + + RD TK S G+A+V F+D A++ Sbjct: 48 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 107 Query: 98 QLNYTPIKGRLCRIMWSQ 115 ++ + GR R+ ++ Sbjct: 108 AMDGAVLDGRELRVQMAR 125 Score = 79.4 bits (194), Expect = 4e-15, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAV 276 T+L V N+ T+ + + +F K+G + + +D + +GF FV + DA A+ Sbjct: 47 MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 106 Query: 277 EALNDSELNGEKLYVGRAQKK 297 +A++ + L+G +L V A+ Sbjct: 107 DAMDGAVLDGRELRVQMARYG 127 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 +L V NL + L F YG + + R +S+GF FV F +A A+ Sbjct: 48 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 107 Query: 381 EKNQQIVAGKPLYVAIAQRKDVRRSQ 406 + ++ G+ L V +A+ S Sbjct: 108 AMDGAVLDGRELRVQMARYGRPPDSH 133 >3CW1-K nrPDB Length = 216 Score = 82.5 bits (202), Expect = 4e-16, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEK-DADGKLKGFGFVNYEKHEDAVKAV 276 + L+V +N +TT+ + + F +GPI + GK +G+ F+ YE D A Sbjct: 102 FKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAY 161 Query: 277 EALNDSELNGEKLYVGRAQKK 297 + + +++G ++ V + + Sbjct: 162 KHADGKKIDGRRVLVDVERGR 182 Score = 64.4 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 29/79 (36%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 +L+V + +E+ L F G + I + + GYA++ + A + Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 99 LNYTPIKGRLCRIMWSQRD 117 + I GR + + Sbjct: 164 ADGKKIDGRRVLVDVERGR 182 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Query: 112 MWSQRDPSLRKKGS-GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIAT-DENGKSKGFG 169 MW + + + +F+ ++ D L F V+G I + +GK +G+ Sbjct: 88 MWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYA 147 Query: 170 FVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKER 207 F+ +E E A +G ++G+ + V R + Sbjct: 148 FIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVK 185 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 LFV ++ + KL EF YG I ++ ++ +GK +G+ F+ + + A Sbjct: 103 KTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 162 Query: 381 EKNQQIVAGKPLYVAIAQRKDVR 403 + + + G+ + V + + + V+ Sbjct: 163 HADGKKIDGRRVLVDVERGRTVK 185 >2KN4-A nrPDB Length = 158 Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKE 181 +G ++ + NL L F +G + I D +S+GF FV F ++ A++ Sbjct: 68 EGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAED 127 Query: 182 AIDALNGMLLNGQEIYVAPHLSRKERDSQLE 212 A+DA++G +L+G+E+ V + DS Sbjct: 128 AMDAMDGAVLDGRELRVQMARYGRPPDSHHS 158 Score = 80.2 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 38/78 (48%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 SL V +L S L +F G V + + RD TK S G+A+V F+D A++ Sbjct: 71 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 130 Query: 98 QLNYTPIKGRLCRIMWSQ 115 ++ + GR R+ ++ Sbjct: 131 AMDGAVLDGRELRVQMAR 148 Score = 79.8 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAV 276 T+L V N+ T+ + + +F K+G + + +D + +GF FV + DA A+ Sbjct: 70 MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 129 Query: 277 EALNDSELNGEKLYVGRAQKK 297 +A++ + L+G +L V A+ Sbjct: 130 DAMDGAVLDGRELRVQMARYG 150 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 +L V NL + L F YG + + R +S+GF FV F +A A+ Sbjct: 71 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 130 Query: 381 EKNQQIVAGKPLYVAIAQRKDVRRSQ 406 + ++ G+ L V +A+ S Sbjct: 131 AMDGAVLDGRELRVQMARYGRPPDSH 156 >1UAW-A nrPDB Length = 77 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 1/78 (1%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 +++G L ++ L + F G V V RD +TK S G+ +V F D K + Sbjct: 1 CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 60 Query: 98 QLNYTPIKGRLCRIMWSQ 115 Q + + + + Sbjct: 61 QSRH-ELDSKTIDPKVAF 77 Score = 71.7 bits (174), Expect = 8e-13, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 2/78 (2%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 +FI L + L + F FG++ + D +S+GFGFV F ++ + + Sbjct: 1 CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL- 59 Query: 185 ALNGMLLNGQEIYVAPHL 202 A + L+ + I Sbjct: 60 AQSRHELDSKTIDPKVAF 77 Score = 66.3 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 +++ ++ +TT E +E F +FG + + +D + +GFGFV + K + Sbjct: 1 CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 60 Query: 278 ALNDSELNGEKLYVGRAQ 295 EL+ + + A Sbjct: 61 QSR-HELDSKTIDPKVAF 77 Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 +F+ L E L E F +G + VMR +S+GFGFV F K + + Sbjct: 2 KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 61 Query: 382 KNQQIVAGKPLYVAIAQ 398 ++ + K + +A Sbjct: 62 -SRHELDSKTIDPKVAF 77 >2DH8-A nrPDB Length = 105 Score = 80.5 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 L+VG L+ S ++ L FS G V + +D T S G+ +V F D + Sbjct: 18 KLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLAS 77 Query: 99 LNYTPIKGRLCRIMW 113 +T + GR Sbjct: 78 RPHT-LDGRNIDPKP 91 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 G +F+ L + L FS +G+++ I D+ +S+GFGFV F++ + Sbjct: 17 GKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLA 76 Query: 185 ALNGMLLNGQEIYVAPHLSRKERDSQ 210 + L+G+ I P R + S Sbjct: 77 S-RPHTLDGRNIDPKPCTPRGMQPSG 101 Score = 72.8 bits (177), Expect = 4e-13, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEA 278 L+V ++ TT E + F+++G +V + KD + +GFGFV ++ V V A Sbjct: 18 KLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPN-CVGTVLA 76 Query: 279 LNDSELNGEKLYVGRAQKKN 298 L+G + + Sbjct: 77 SRPHTLDGRNIDPKPCTPRG 96 Score = 68.6 bits (166), Expect = 7e-12, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITE 381 LFV LD S E L F+ YG + +M+ + +S+GFGFV F P + Sbjct: 18 KLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLAS 77 Query: 382 KNQQIVAGKPLYVAIAQRKDVRRS 405 + + G+ + + ++ S Sbjct: 78 RPHT-LDGRNIDPKPCTPRGMQPS 100 >5X3Y-A nrPDB Length = 96 Score = 80.5 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Query: 216 AHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVK 274 +H ++V ++ TT E + F +FG + A L D + +GFGFV +E ED V+ Sbjct: 2 SHMKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES-EDIVE 60 Query: 275 AVEALNDSELNGEKLYVGRAQKKNERM 301 V ++ E+N + + +AQ K Sbjct: 61 KVCEIHFHEINNKMVECKKAQPKEVMS 87 Score = 65.9 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 34/89 (38%), Gaps = 1/89 (1%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 ++VG L + + + F G V + D T G+ +V F E + + + Sbjct: 6 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES-EDIVEKVCE 64 Query: 99 LNYTPIKGRLCRIMWSQRDPSLRKKGSGN 127 +++ I ++ +Q + GS Sbjct: 65 IHFHEINNKMVECKKAQPKEVMSPTGSAR 93 Score = 65.5 bits (158), Expect = 6e-11, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAI 183 IF+ L + + + F FG + + + D+ + +GFGFV FE E ++ Sbjct: 4 MKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVC 63 Query: 184 DALNGMLLNGQEIYVAPHLSR 204 + ++ +N + + + Sbjct: 64 E-IHFHEINNKMVECKKAQPK 83 Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 +FV L + E ++ F +G + A +M + + +GFGFV F + + K Sbjct: 5 KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 64 Query: 381 EKNQQIVAGKPLYVAIAQRKDV 402 + + K + AQ K+V Sbjct: 65 -IHFHEINNKMVECKKAQPKEV 85 >6QX9-1K nrPDB Length = 437 Score = 80.2 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEK-DADGKLKGFGFVNYEKHEDAVKAV 276 + L+V +N +TT+ + + F +GPI + GK +G+ F+ YE D A Sbjct: 102 FKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAY 161 Query: 277 EALNDSELNGEKLYVGRAQKK 297 + + +++G ++ V + + Sbjct: 162 KHADGKKIDGRRVLVDVERGR 182 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 29/79 (36%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 +L+V + +E+ L F G + I + + GYA++ + A + Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 99 LNYTPIKGRLCRIMWSQRD 117 + I GR + + Sbjct: 164 ADGKKIDGRRVLVDVERGR 182 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Query: 112 MWSQRDPSLRKKGS-GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIAT-DENGKSKGFG 169 MW + + + +F+ ++ D L F V+G I + +GK +G+ Sbjct: 88 MWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYA 147 Query: 170 FVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKER 207 F+ +E E A +G ++G+ + V R + Sbjct: 148 FIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVK 185 Score = 55.9 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 LFV ++ + KL EF YG I ++ ++ +GK +G+ F+ + + A Sbjct: 103 KTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYK 162 Query: 381 EKNQQIVAGKPLYVAIAQRKDVR 403 + + + G+ + V + + + V+ Sbjct: 163 HADGKKIDGRRVLVDVERGRTVK 185 >6G90-B nrPDB Length = 300 Score = 79.8 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 3/92 (3%) Query: 29 ESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFND 88 + ++++G L + E L F G + IR+ +D IT+ S GYA++ F D Sbjct: 98 PHIKDTDPYRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKD 157 Query: 89 HEAGRKAIEQLN---YTPIKGRLCRIMWSQRD 117 + + A +++ IK R+C + + Sbjct: 158 PISSKMAFKEIGVHRGIQIKDRICIVDIERGR 189 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 IFI L D+D L F FG+I +I D+ KSKG+ F+ F++ ++K A Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 185 ALN---GMLLNGQEIYVAPHLSRKER 207 + G+ + + V R + Sbjct: 167 EIGVHRGIQIKDRICIVDIERGRTVK 192 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 +F+ L +D+ +L++ F +G I ++++ + KSKG+ F+ F P + A Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 381 EKN---QQIVAGKPLYVAIAQRKDVR 403 E + + V I + + V+ Sbjct: 167 EIGVHRGIQIKDRICIVDIERGRTVK 192 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 35/84 (41%), Gaps = 4/84 (4%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAV 276 Y +++ + + + + Q+ F KFG I + KD K KG+ F+ ++ + A Sbjct: 106 YRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAF 165 Query: 277 EAL---NDSELNGEKLYVGRAQKK 297 + + ++ V + + Sbjct: 166 KEIGVHRGIQIKDRICIVDIERGR 189 >5ZWN-Q nrPDB Length = 300 Score = 79.4 bits (194), Expect = 5e-15, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 3/92 (3%) Query: 29 ESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFND 88 + ++++G L + E L F G + IR+ +D IT+ S GYA++ F D Sbjct: 98 PHIKDTDPYRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKD 157 Query: 89 HEAGRKAIEQLN---YTPIKGRLCRIMWSQRD 117 + + A +++ IK R+C + + Sbjct: 158 PISSKMAFKEIGVHRGIQIKDRICIVDIERGR 189 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 IFI L D+D L F FG+I +I D+ KSKG+ F+ F++ ++K A Sbjct: 107 RTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFK 166 Query: 185 ALN---GMLLNGQEIYVAPHLSRKER 207 + G+ + + V R + Sbjct: 167 EIGVHRGIQIKDRICIVDIERGRTVK 192 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 50/118 (42%), Gaps = 7/118 (5%) Query: 290 YVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTIT 349 + AQ + R+ ++ Y+ +F+ L +D+ +L++ F +G I Sbjct: 78 KIKNAQLLDRRLQNWNPNV-DPHIKDTDPYR--TIFIGRLPYDLDEIELQKYFVKFGEIE 134 Query: 350 SAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKN---QQIVAGKPLYVAIAQRKDVR 403 ++++ + KSKG+ F+ F P + A E + + V I + + V+ Sbjct: 135 KIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRTVK 192 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 35/84 (41%), Gaps = 4/84 (4%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAV 276 Y +++ + + + + Q+ F KFG I + KD K KG+ F+ ++ + A Sbjct: 106 YRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAF 165 Query: 277 EAL---NDSELNGEKLYVGRAQKK 297 + + ++ V + + Sbjct: 166 KEIGVHRGIQIKDRICIVDIERGR 189 >2DYD-A nrPDB Length = 85 Score = 79.0 bits (193), Expect = 5e-15, Method: Composition-based stats. Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Query: 489 GFPRNA--NDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLL 546 G P A + + QR LGE LY V ++ A K+TGM+L++ EV LL Sbjct: 4 GSPIGALASALANSPPETQRMMLGENLYPLVDQLEHDQ--AAKVTGMLLEMDQTEVLHLL 61 Query: 547 ESDELFEQHYKEASAAYESFKK 568 ES + + EA S ++ Sbjct: 62 ESPDALKAKVAEAMEVLRSAQQ 83 >2CPD-A nrPDB Length = 99 Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKF--GPIVSASLEKDADGKLKGFG 262 S E+T + LYV+N+ T++E ++ F G + +D + Sbjct: 2 SSGSSGDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YA 54 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERM 301 FV++ EDAV+A++ALN L+G + V A+ ++ Sbjct: 55 FVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 93 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 324 LFVKNLDDSVDDEKLEEEFAPY--GTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITE 381 L+V+NL S +E +E+EF G + K +R + FV FS E+A +A+ Sbjct: 18 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVEAMKA 70 Query: 382 KNQQIVAGKPLYVAIAQRKDVRRS 405 N +++ G P+ V +A+ D S Sbjct: 71 LNGKVLDGSPIEVTLAKPVDKDSS 94 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 9/85 (10%) Query: 128 IFIKNLHPDIDNKALYDTFSVF--GDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDA 185 ++++NL + + F+ G + K D + FVHF A EA+ A Sbjct: 18 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVEAMKA 70 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQ 210 LNG +L+G I V + S Sbjct: 71 LNGKVLDGSPIEVTLAKPVDKDSSG 95 Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 10/105 (9%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPI--GSVSSIRVCRDAITKTSLGY 81 ++ S + +S LYV +L S SE + F+ I G+V ++ RD Y Sbjct: 2 SSGSSGDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD--------Y 53 Query: 82 AYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 A+V+F++ E +A++ LN + G + ++ S Sbjct: 54 AFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSSGPSS 98 >2DGP-A nrPDB Length = 106 Score = 77.5 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 114 SQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVH 172 S ++ + +FI + ++D K L F FG I + D G KG F+ Sbjct: 2 SSGSSGMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLT 61 Query: 173 FEEEGAAKEAIDALNGMLL---NGQEIYVAPH 201 + E +A +A AL+ + I V P Sbjct: 62 YCERESALKAQSALHEQKTLPGMNRPIQVKPA 93 Score = 74.8 bits (182), Expect = 9e-14, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 39/89 (43%), Gaps = 2/89 (2%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAY 83 ++GS ++ L++G + ++ E L +F G + + V +D T G A+ Sbjct: 1 GSSGSSGMKDHDA-IKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAF 59 Query: 84 VNFNDHEAGRKAIEQLNY-TPIKGRLCRI 111 + + + E+ KA L+ + G I Sbjct: 60 LTYCERESALKAQSALHEQKTLPGMNRPI 88 Score = 69.8 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 316 MAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEE 374 M + + LF+ + ++D++ L+ F +G I V++ G KG F+ + E Sbjct: 8 MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERES 67 Query: 375 ATKAITEKNQQI---VAGKPLYVAIA 397 A KA + ++Q +P+ V A Sbjct: 68 ALKAQSALHEQKTLPGMNRPIQVKPA 93 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEA 278 L++ I ++ + LF +FG I ++ KD G KG F+ Y + E A+KA A Sbjct: 15 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 74 Query: 279 LNDSEL---NGEKLYVGRA 294 L++ + + V A Sbjct: 75 LHEQKTLPGMNRPIQVKPA 93 >2EVZ-A nrPDB Length = 229 Score = 77.5 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 77/202 (38%), Gaps = 26/202 (12%) Query: 216 AHYTNLYVKNINSE-TTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 A + L V N+N E T + LF +G + + + K V A Sbjct: 32 AGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNK----KENALVQMADGNQAQL 87 Query: 275 AVEALNDSELNGEKLYVGRAQKKNERM-------HVLKKQYEAYRLEKMAKYQGVN---- 323 A+ LN +L+G+ + + ++ +N ++ L K Y L + K N Sbjct: 88 AMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNI 147 Query: 324 ------LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 L + N+ SV +E L+ F+ G + ++ + + + EEA + Sbjct: 148 FPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKD---RKMALIQMGSVEEAVQ 204 Query: 378 AITEKNQQIV-AGKPLYVAIAQ 398 A+ + + + L V+ ++ Sbjct: 205 ALIDLHNHDLGENHHLRVSFSK 226 Score = 75.9 bits (185), Expect = 4e-14, Method: Composition-based stats. Identities = 41/209 (19%), Positives = 77/209 (36%), Gaps = 36/209 (17%) Query: 116 RDPSLRKKGSGNIFIKNL-HPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFE 174 P L G+ + + NL + ++L+ F V+GD+ KI ++ K V Sbjct: 25 AIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNK----KENALVQMA 80 Query: 175 EEGAAKEAIDALNGMLLNGQEIY--------VAPHLSRKERDSQLEETKAHY-------- 218 + A+ A+ LNG L+G+ I V +E ++ Sbjct: 81 DGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPG 140 Query: 219 -----------TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYE 267 L++ NI ++E + LF+ G +V K + + Sbjct: 141 SKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKG---FKFFQKDRKMALIQMG 197 Query: 268 KHEDAVKAVEALNDSELN-GEKLYVGRAQ 295 E+AV+A+ L++ +L L V ++ Sbjct: 198 SVEEAVQALIDLHNHDLGENHHLRVSFSK 226 Score = 69.0 bits (167), Expect = 5e-12, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 65/203 (32%), Gaps = 43/203 (21%) Query: 37 SASLYVGDLEPS-VSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 ++ L V +L P V+ L+ +F G V +++ + A V D + A Sbjct: 34 NSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKEN-----ALVQMADGNQAQLA 88 Query: 96 IEQLNYTPIKGRLCRIMWSQ--------------------------RDPSLRKKGSGNIF 129 + LN + G+ RI S+ R K NIF Sbjct: 89 MSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIF 148 Query: 130 -------IKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 + N+ P + + L FS G ++ K + + A +A Sbjct: 149 PPSATLHLSNIPPSVSEEDLKVLFSSNGGVVK---GFKFFQKDRKMALIQMGSVEEAVQA 205 Query: 183 IDALNGMLL-NGQEIYVAPHLSR 204 + L+ L + V+ S Sbjct: 206 LIDLHNHDLGENHHLRVSFSKST 228 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 41/94 (43%), Gaps = 5/94 (5%) Query: 321 GVNLFVKNL-DDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAI 379 L V NL + V + L F YG + K++ + V + +A A+ Sbjct: 34 NSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKEN----ALVQMADGNQAQLAM 89 Query: 380 TEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQA 413 + N + GKP+ + +++ ++V+ + Q+ Q Sbjct: 90 SHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQG 123 >2DGQ-A nrPDB Length = 108 Score = 77.1 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 37/96 (38%), Gaps = 4/96 (4%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEG 177 ++ + +F+ + +D + L F FG I + D G KG F+ + Sbjct: 9 PMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARD 68 Query: 178 AAKEAIDALNGMLL---NGQEIYVAPHLSRKERDSQ 210 +A +A AL+ + I V P S +S Sbjct: 69 SALKAQSALHEQKTLPGMNRPIQVKPAASEGRGESG 104 Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 42/103 (40%), Gaps = 2/103 (1%) Query: 24 AATGSESQSVENSSA-SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 ++GS +++ A L+VG + + E L +F G + + V +D +T G A Sbjct: 1 GSSGSSGVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCA 60 Query: 83 YVNFNDHEAGRKAIEQLNY-TPIKGRLCRIMWSQRDPSLRKKG 124 ++ + ++ KA L+ + G I R + Sbjct: 61 FLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGES 103 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPE 373 M + + LFV + +D++ L+ F +G I V++ G KG F+ + + Sbjct: 9 PMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARD 68 Query: 374 EATKAITEKNQQI---VAGKPLYVAIA 397 A KA + ++Q +P+ V A Sbjct: 69 SALKAQSALHEQKTLPGMNRPIQVKPA 95 Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 4/100 (4%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGF 263 S + L+V I ++ + LF +FG I ++ KD G KG F Sbjct: 2 SSGSSGVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAF 61 Query: 264 VNYEKHEDAVKAVEALNDSEL---NGEKLYVGRAQKKNER 300 + Y + A+KA AL++ + + V A + Sbjct: 62 LTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRG 101 >2DGS-A nrPDB Length = 99 Score = 76.7 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 2/84 (2%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADG-KLKGFGFVNYEKHEDAVKAVE 277 ++V I + + +E F KFG + + DA+ + +GFGF+ +E + +AV Sbjct: 11 NKIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN 70 Query: 278 ALNDSELNGEKLYVGRAQKKNERM 301 ++ ++ G+K+ V RA+ ++ + Sbjct: 71 -MHFHDIMGKKVEVKRAEPRDSKS 93 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 2/85 (2%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATD-ENGKSKGFGFVHFEEEGAAKEAIDA 185 IF+ + + L + F FG + + D E + +GFGF+ FE+E + +A+ Sbjct: 12 KIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAV-N 70 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQ 210 ++ + G+++ V R + S Sbjct: 71 MHFHDIMGKKVEVKRAEPRDSKSSG 95 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT-ENGKSKGFGFVCFSTPEEATKAITE 381 +FV + + + +L E F +G +T ++ E + +GFGF+ F + +A+ Sbjct: 12 KIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAV-N 70 Query: 382 KNQQIVAGKPLYVAIAQRKDVRRS 405 + + GK + V A+ +D + S Sbjct: 71 MHFHDIMGKKVEVKRAEPRDSKSS 94 Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 ++VG + + E L + F G V+ + + DA + G+ ++ F D ++ +A+ Sbjct: 11 NKIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN 70 Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 +++ I G+ + ++ S S Sbjct: 71 -MHFHDIMGKKVEVKRAEPRDSKSSGPSS 98 >1QM9-A nrPDB Length = 198 Score = 76.3 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 38/197 (19%), Positives = 75/197 (38%), Gaps = 26/197 (13%) Query: 221 LYVKNINSE-TTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEAL 279 L V N+N E T + LF +G + + + K V A A+ L Sbjct: 6 LLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNK----KENALVQMADGNQAQLAMSHL 61 Query: 280 NDSELNGEKLYVGRAQKKNERM-------HVLKKQYEAYRLEKMAKYQGVN--------- 323 N +L+G+ + + ++ +N ++ L K Y L + K N Sbjct: 62 NGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSA 121 Query: 324 -LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEK 382 L + N+ SV +E L+ F+ G + ++ + + + EEA +A+ + Sbjct: 122 TLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKD---RKMALIQMGSVEEAVQALIDL 178 Query: 383 NQQIV-AGKPLYVAIAQ 398 + + L V+ ++ Sbjct: 179 HNHDLGENHHLRVSFSK 195 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 39/201 (19%), Positives = 75/201 (37%), Gaps = 36/201 (17%) Query: 124 GSGNIFIKNL-HPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 G+ + + NL + ++L+ F V+GD+ KI ++ K V + A+ A Sbjct: 2 GNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNK----KENALVQMADGNQAQLA 57 Query: 183 IDALNGMLLNGQEIY--------VAPHLSRKERDSQLEETKAHY---------------- 218 + LNG L+G+ I V +E ++ Sbjct: 58 MSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIF 117 Query: 219 ---TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKA 275 L++ NI ++E + LF+ G +V K + + E+AV+A Sbjct: 118 PPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKG---FKFFQKDRKMALIQMGSVEEAVQA 174 Query: 276 VEALNDSELN-GEKLYVGRAQ 295 + L++ +L L V ++ Sbjct: 175 LIDLHNHDLGENHHLRVSFSK 195 Score = 68.2 bits (165), Expect = 9e-12, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 65/203 (32%), Gaps = 43/203 (21%) Query: 37 SASLYVGDLEPS-VSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 ++ L V +L P V+ L+ +F G V +++ + A V D + A Sbjct: 3 NSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKEN-----ALVQMADGNQAQLA 57 Query: 96 IEQLNYTPIKGRLCRIMWSQ--------------------------RDPSLRKKGSGNIF 129 + LN + G+ RI S+ R K NIF Sbjct: 58 MSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIF 117 Query: 130 -------IKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 + N+ P + + L FS G ++ K + + A +A Sbjct: 118 PPSATLHLSNIPPSVSEEDLKVLFSSNGGVVK---GFKFFQKDRKMALIQMGSVEEAVQA 174 Query: 183 IDALNGMLL-NGQEIYVAPHLSR 204 + L+ L + V+ S Sbjct: 175 LIDLHNHDLGENHHLRVSFSKST 197 Score = 56.3 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 41/94 (43%), Gaps = 5/94 (5%) Query: 321 GVNLFVKNL-DDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAI 379 L V NL + V + L F YG + K++ + V + +A A+ Sbjct: 3 NSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKEN----ALVQMADGNQAQLAM 58 Query: 380 TEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQA 413 + N + GKP+ + +++ ++V+ + Q+ Q Sbjct: 59 SHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQG 92 >2MST-A nrPDB Length = 75 Score = 75.9 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Query: 220 NLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEA 278 ++V ++ TT E + F +FG + A L D + +GFGFV +E ED V+ V Sbjct: 1 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES-EDIVEKVCE 59 Query: 279 LNDSELNGEKLYVGRA 294 ++ E+N + + +A Sbjct: 60 IHFHEINNKMVECKKA 75 Score = 65.5 bits (158), Expect = 5e-11, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDA 185 IF+ L + + + F FG + + + D+ + +GFGFV FE E ++ + Sbjct: 1 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE- 59 Query: 186 LNGMLLNGQEIYVAPH 201 ++ +N + + Sbjct: 60 IHFHEINNKMVECKKA 75 Score = 65.1 bits (157), Expect = 7e-11, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 30/76 (39%), Gaps = 1/76 (1%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQ 98 ++VG L + + + F G V + D T G+ +V F E + + + Sbjct: 1 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES-EDIVEKVCE 59 Query: 99 LNYTPIKGRLCRIMWS 114 +++ I ++ + Sbjct: 60 IHFHEINNKMVECKKA 75 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT- 380 +FV L + E ++ F +G + A +M + + +GFGFV F + + K Sbjct: 1 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEI 60 Query: 381 ---EKNQQIVAGKP 391 E N ++V K Sbjct: 61 HFHEINNKMVECKK 74 >6AH0-p nrPDB Length = 225 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 46/265 (17%), Positives = 85/265 (32%), Gaps = 50/265 (18%) Query: 37 SASLYVGDLEPSVSEAHL----YDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAG 92 + ++Y+ ++ + + L Y +FS G V I + T G A+V F + + Sbjct: 6 NHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALK---TMKMRGQAFVIFKELGSS 62 Query: 93 RKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDI 152 A+ QL P G+ RI +++ D+ + F D Sbjct: 63 TNALRQLQGFPFYGKPMRIQYAK---------------------TDSDIISKMRGTFADK 101 Query: 153 LSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLE 212 K + ++ N G A + Q+ Sbjct: 102 EKKKEKK---------------KAKTVEQTATTTNKKPGQGTP-NSANTQGNSTPNPQVP 145 Query: 213 ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDA 272 + +Y L++ N+ ET + LF +F L FV +E A Sbjct: 146 DYPPNY-ILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRH----DIAFVEFENDGQA 200 Query: 273 VKAVEALNDSEL-NGEKLYVGRAQK 296 A +AL ++ + + A+K Sbjct: 201 GAARDALQGFKITPSHAMKITYAKK 225 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 32/224 (14%), Positives = 68/224 (30%), Gaps = 50/224 (22%) Query: 220 NLYVKNINSETTDEQFQE----LFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKA 275 +Y+ N+N + E+ + LF++FG +V K++G FV +++ + A Sbjct: 8 TIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVAL--KTMKMRGQAFVIFKELGSSTNA 65 Query: 276 VEALNDSELNGEKLYVGRA-------------------------------------QKKN 298 + L G+ + + A +K Sbjct: 66 LRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTNKKPG 125 Query: 299 ERMHVLKKQYEAYRLEKMAKYQGVN--LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRT 356 + N LF+ NL + ++ L F + +++ Sbjct: 126 QGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPG 185 Query: 357 ENGKSKGFGFVCFSTPEEATKAITEKNQ-QIVAGKPLYVAIAQR 399 + FV F +A A +I + + A++ Sbjct: 186 RHD----IAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK 225 Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 15/112 (13%), Positives = 37/112 (33%), Gaps = 6/112 (5%) Query: 5 TDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSV 64 T + + + + +T + + L++ +L +E L +F+ Sbjct: 118 TTTNKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGF 177 Query: 65 SSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPI-KGRLCRIMWSQ 115 +R+ A+V F + A + L I +I +++ Sbjct: 178 KEVRLVPGRHD-----IAFVEFENDGQAGAARDALQGFKITPSHAMKITYAK 224 >4WKR-A nrPDB Length = 208 Score = 72.4 bits (176), Expect = 5e-13, Method: Composition-based stats. Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 191 LNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASL 250 L G I L + +D +YV+ + + +F K G +V S+ Sbjct: 104 LEGTRIRRKKPLGERPKDE-------DERTVYVELLPKNVNHSWIERVFGKCGNVVYISI 156 Query: 251 EK-DADGKLKGFGFVNYEKHEDAVKAVEALND 281 + G KGF FV +E E A KA+E LN+ Sbjct: 157 PHYKSTGDPKGFAFVEFETKEQAAKAIEFLNN 188 Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 40/89 (44%) Query: 15 LNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAI 74 L+++ + + + + ++YV L +V+ + + +F G+V I + Sbjct: 102 LDLEGTRIRRKKPLGERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKS 161 Query: 75 TKTSLGYAYVNFNDHEAGRKAIEQLNYTP 103 T G+A+V F E KAIE LN P Sbjct: 162 TGDPKGFAFVEFETKEQAAKAIEFLNNPP 190 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 104 IKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIA-TDEN 162 ++G R + + + ++++ L ++++ + F G+++ I Sbjct: 104 LEGTRIRRKKPLGERP-KDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKST 162 Query: 163 GKSKGFGFVHFEEEGAAKEAIDALNG 188 G KGF FV FE + A +AI+ LN Sbjct: 163 GDPKGFAFVEFETKEQAAKAIEFLNN 188 Score = 59.7 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 1/85 (1%) Query: 301 MHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NG 359 + + + + E+ ++V+ L +V+ +E F G + + + G Sbjct: 104 LEGTRIRRKKPLGERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTG 163 Query: 360 KSKGFGFVCFSTPEEATKAITEKNQ 384 KGF FV F T E+A KAI N Sbjct: 164 DPKGFAFVEFETKEQAAKAIEFLNN 188 >2MKI-A nrPDB Length = 203 Score = 70.9 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 32/178 (17%), Positives = 70/178 (39%), Gaps = 19/178 (10%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKS----KGFGFVHFE 174 ++ S +F+ L PDID + +F FG ++ KS KG+ F+ F+ Sbjct: 6 ERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLI-VDWPHKAESKSYFPPKGYAFLLFQ 64 Query: 175 EEGAAK---EAIDALNGM--------LLNGQEIYVAP-HLSRKERDSQLEETKAHYTNLY 222 +E + + +A +G + + + + P +LS + + ++ Sbjct: 65 DESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 124 Query: 223 VKNINSETTDEQFQELFAK-FGPIVSASLEKDAD-GKLKGFGFVNYEKHEDAVKAVEA 278 V + + + + +G + A ++ D + KG G V + + + A+ A Sbjct: 125 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISA 182 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 70/199 (35%), Gaps = 31/199 (15%) Query: 30 SQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK---TSLGYAYVNF 86 + VE S ++VG L P + E + F G + + A +K GYA++ F Sbjct: 5 GERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLI-VDWPHKAESKSYFPPKGYAFLLF 63 Query: 87 NDHEAGRKAIEQ-----------LNYTPIKGRLCRIMWSQRDPSLRKKG-------SGNI 128 D + + I+ ++ IK + +I S I Sbjct: 64 QDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTI 123 Query: 129 FIKNLHPDIDNKALYDTFSV-FGDILSSKIATDENGK-SKGFGFVHFEEEGAAKEAIDA- 185 F+ + + L +G + + I TD K KG G V F + + AI A Sbjct: 124 FVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISAR 183 Query: 186 ----LNGMLLNGQEIYVAP 200 +G + + + V P Sbjct: 184 FVQLQHGEI--DKRVEVKP 200 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 23/64 (35%), Gaps = 5/64 (7%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKS----KGFGFVCFSTPEEATK 377 +FV L +D++++ F +G + KS KG+ F+ F Sbjct: 13 RKVFVGGLPPDIDEDEITASFRRFGPLI-VDWPHKAESKSYFPPKGYAFLLFQDESSVQA 71 Query: 378 AITE 381 I Sbjct: 72 LIDA 75 >6EM1-o nrPDB Length = 220 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 72/169 (42%), Gaps = 18/169 (10%) Query: 174 EEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDE 233 ++E + I LN + +++ + + + +YV + ++ Sbjct: 57 DDEQSGTHKIKRLNP-----------KKQANEKKSKDKKTLEEYSGIIYVSRLPHGFHEK 105 Query: 234 QFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVG 292 + + FA+FG + L ++ G + +GF+ + EDA+ A E++N+ L G L V Sbjct: 106 ELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQV- 164 Query: 293 RAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEE 341 R K ++ L K + +EK G+ VK L D++ + E Sbjct: 165 RVLPKGAKIEKLYKYKKRVLVEK-----GITKPVKQLKDNMKQKHEERI 208 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 39/92 (42%) Query: 20 DQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSL 79 Q + +++E S +YV L E L F+ G + +R+ R+ T S Sbjct: 73 KQANEKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSR 132 Query: 80 GYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRI 111 Y ++ F + E A E +N + G L ++ Sbjct: 133 HYGFLEFVNKEDAMIAQESMNNYLLMGHLLQV 164 Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 6/113 (5%) Query: 88 DHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFS 147 D ++G I++LN +D ++ SG I++ L K L F+ Sbjct: 58 DEQSGTHKIKRLNPKKQAN-----EKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFA 112 Query: 148 VFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA 199 FGD+ ++A ++ G S+ +GF+ F + A A +++N LL G + V Sbjct: 113 QFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVR 165 Score = 61.7 bits (148), Expect = 9e-10, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Query: 305 KKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKG 363 + + + +K + ++V L +++L + FA +G + ++ R + G S+ Sbjct: 74 QANEKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRH 133 Query: 364 FGFVCFSTPEEATKAITEKNQQIVAGKPLYVA 395 +GF+ F E+A A N ++ G L V Sbjct: 134 YGFLEFVNKEDAMIAQESMNNYLLMGHLLQVR 165 >4CQ1-A nrPDB Length = 196 Score = 69.0 bits (167), Expect = 6e-12, Method: Composition-based stats. Identities = 39/200 (19%), Positives = 73/200 (36%), Gaps = 29/200 (14%) Query: 219 TNLYVKNINSET-TDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVE 277 T L V N+N E T + LF +G + + + K + + A+ Sbjct: 3 TVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNK----KDSALIQMADGNQSQLAMN 58 Query: 278 ALNDSELNGEKLYVGRAQKKNERM-------HVLKKQYEAYRLEKMAKYQGVN------- 323 LN ++ G+ + V ++ + ++ L K + L + K N Sbjct: 59 HLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPP 118 Query: 324 ---LFVKNLDDSVDDEKLEEEFAPYGTITSA-KVMRTENGKSKGFGFVCFSTPEEATKAI 379 L + N+ SV +E L FA G A K + + +T EEA +A+ Sbjct: 119 SATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHK-----MALLQMATVEEAIQAL 173 Query: 380 TEKNQQIV-AGKPLYVAIAQ 398 + + + L V+ ++ Sbjct: 174 IDLHNYNLGENHHLRVSFSK 193 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 75/202 (37%), Gaps = 39/202 (19%) Query: 124 GSGNIFIKNLHPDI-DNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 G+ + + NL+ ++ ++L+ F V+GD+ KI ++ K + + ++ A Sbjct: 1 GNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNK----KDSALIQMADGNQSQLA 56 Query: 183 IDALNGMLLNGQEIYVAP---------------------------HLSRKERDSQLEETK 215 ++ LNG + G+ I V H +K + Sbjct: 57 MNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIF 116 Query: 216 AHYTNLYVKNINSETTDEQFQELFAKF-GPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 L++ NI +E + LFA G + + +D + E+A++ Sbjct: 117 PPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHK-----MALLQMATVEEAIQ 171 Query: 275 AVEALNDSELN-GEKLYVGRAQ 295 A+ L++ L L V ++ Sbjct: 172 ALIDLHNYNLGENHHLRVSFSK 193 Score = 66.7 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 64/204 (31%), Gaps = 46/204 (22%) Query: 37 SASLYVGDLEPSV-SEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 + L V +L + + L+ +F G V +++ + A + D + A Sbjct: 2 NTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDS-----ALIQMADGNQSQLA 56 Query: 96 IEQLNYTPIKGRLCRIMWSQ--------------------------RDPSLRKKGSGNIF 129 + LN + G++ R+ S+ R K NIF Sbjct: 57 MNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIF 116 Query: 130 -------IKNLHPDIDNKALYDTFSVFGDILSS-KIATDENGKSKGFGFVHFEEEGAAKE 181 + N+ P + + L F+ G + + K D + A + Sbjct: 117 PPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHK-----MALLQMATVEEAIQ 171 Query: 182 AIDALNGMLL-NGQEIYVAPHLSR 204 A+ L+ L + V+ S Sbjct: 172 ALIDLHNYNLGENHHLRVSFSKST 195 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 37/84 (44%), Gaps = 5/84 (5%) Query: 321 GVNLFVKNLDDSV-DDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAI 379 L V NL++ + + L F YG + K++ + K + + ++ A+ Sbjct: 2 NTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNK----KDSALIQMADGNQSQLAM 57 Query: 380 TEKNQQIVAGKPLYVAIAQRKDVR 403 N Q + GK + V +++ + V+ Sbjct: 58 NHLNGQKMYGKIIRVTLSKHQTVQ 81 >1X4A-A nrPDB Length = 109 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAI 183 I++ NL PDI K + D F +G I + G F FV FE+ A++A+ Sbjct: 21 NDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPP--FAFVEFEDPRDAEDAV 78 Query: 184 DALNGMLLNGQEIYVAPHLS 203 +G +G + V S Sbjct: 79 YGRDGYDYDGYRLRVEFPRS 98 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 +YV N+ + + +++F K+G I L+ G F FV +E DA AV Sbjct: 23 CRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPP--FAFVEFEDPRDAEDAVYG 80 Query: 279 LNDSELNGEKLYVGRAQ 295 + + +G +L V + Sbjct: 81 RDGYDYDGYRLRVEFPR 97 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 36/93 (38%), Gaps = 3/93 (3%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 N+ +YVG+L P + + D+F G++ I + ++ +A+V F D Sbjct: 19 GNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDL-KNRRGGPP--FAFVEFEDPRDAE 75 Query: 94 KAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 A+ + G R+ + + S Sbjct: 76 DAVYGRDGYDYDGYRLRVEFPRSGRGTGSGPSS 108 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 317 AKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEAT 376 A ++V NL + + +E+ F YG I + G F FV F P +A Sbjct: 18 AGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPP--FAFVEFEDPRDAE 75 Query: 377 KAITEKNQQIVAGKPLYVAIAQ 398 A+ ++ G L V + Sbjct: 76 DAVYGRDGYDYDGYRLRVEFPR 97 >2I2Y-A nrPDB Length = 150 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAID 184 +++ NL + + L F +G + S +A + GF FV FE+ A +A+ Sbjct: 73 DCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARN----PPGFAFVEFEDPRDAADAVR 128 Query: 185 ALNGMLLNGQEIYVAPHLSRK 205 L+G L G + V K Sbjct: 129 ELDGRTLCGCRVRVELSNGEK 149 Score = 66.3 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 4/82 (4%) Query: 213 ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDA 272 ++ +YV N+ + + + F +GP+ S + ++ GF FV +E DA Sbjct: 68 DSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARN----PPGFAFVEFEDPRDA 123 Query: 273 VKAVEALNDSELNGEKLYVGRA 294 AV L+ L G ++ V + Sbjct: 124 ADAVRELDGRTLCGCRVRVELS 145 Score = 61.7 bits (148), Expect = 8e-10, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 319 YQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 ++V NL ++ + +LE F YG + S V R GF FV F P +A A Sbjct: 71 PLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPP----GFAFVEFEDPRDAADA 126 Query: 379 ITEKNQQIVAGKPLYVAIA 397 + E + + + G + V ++ Sbjct: 127 VRELDGRTLCGCRVRVELS 145 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 +YVG+L + ++ L F G + S+ V R+ G+A+V F D A+ Sbjct: 73 DCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPP-----GFAFVEFEDPRDAADAV 127 Query: 97 EQLNYTPIKGRLCRIMWSQRDPS 119 +L+ + G R+ S + Sbjct: 128 RELDGRTLCGCRVRVELSNGEKR 150 >6FYY-r nrPDB Length = 274 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 41/206 (19%), Positives = 68/206 (33%), Gaps = 7/206 (3%) Query: 95 AIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS 154 A+ ++ RL R W Q + +K ++ L + F ILS Sbjct: 70 AVTARLGEEVELRLSR-NWKQAEEERIQKEKASLTKTGLQCRLCGNDHMTMNCPFKTILS 128 Query: 155 -SKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEE 213 D G E+ G A + + S RDS+ + Sbjct: 129 ELSALEDPATSEGGVEAASEEKAGQVGGAGSIPGQYVPPSRRAGARDPSSDAYRDSRERD 188 Query: 214 TKAHYTNLYVKNINSETTDEQFQE-LFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHED 271 L + +N + +E L F PI S+ ++ GK +G FV + E Sbjct: 189 ---DMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEV 245 Query: 272 AVKAVEALNDSELNGEKLYVGRAQKK 297 A +A+ L+ L V ++ K Sbjct: 246 AEQALRFLDGRGYMNLILRVEWSKPK 271 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 38/93 (40%), Gaps = 1/93 (1%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYD-IFSPIGSVSSIRVCRDAITKTSLGYA 82 ++ + +L + + + E L + + P + + V R+ T S G A Sbjct: 177 SSDAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLA 236 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 +V F+ E +A+ L+ + R+ WS+ Sbjct: 237 FVTFSSEEVAEQALRFLDGRGYMNLILRVEWSK 269 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 37/99 (37%), Gaps = 2/99 (2%) Query: 111 IMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYD-TFSVFGDILSSKIATDE-NGKSKGF 168 S + + I ++ + D +L + F I + ++ GKS+G Sbjct: 176 PSSDAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGL 235 Query: 169 GFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKER 207 FV F E A++A+ L+G + V + + Sbjct: 236 AFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE 274 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 55/135 (40%), Gaps = 3/135 (2%) Query: 268 KHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVK 327 E V+A ++ G G+ + R +AYR + L + Sbjct: 138 TSEGGVEAASEEKAGQVGGAGSIPGQYVPPSRRAGARDPSSDAYRDSRERDDMCT-LKIM 196 Query: 328 NLDDSVDDEKLEE-EFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQ 385 ++++ D+ L E P+ I V+R + GKS+G FV FS+ E A +A+ + + Sbjct: 197 QVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGR 256 Query: 386 IVAGKPLYVAIAQRK 400 L V ++ K Sbjct: 257 GYMNLILRVEWSKPK 271 >6H7A-A nrPDB Length = 92 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 2/77 (2%) Query: 491 PRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDE 550 P + Q+QR ALG++L+ KV E A KITGM L++ P+E + LL + Sbjct: 16 PITPQELESMSPQEQRAALGDRLFLKVYEIA--PELAPKITGMFLEMKPKEAYELLNDQK 73 Query: 551 LFEQHYKEASAAYESFK 567 E+ EA ++ + Sbjct: 74 RLEERVTEALCVLKAHQ 90 >2BZ2-A nrPDB Length = 121 Score = 66.3 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 40/103 (38%), Gaps = 7/103 (6%) Query: 298 NERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE 357 H+ + E+ A +G L+V + + L F+P+G I + Sbjct: 16 PRGSHMGPFRRSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM--DP 71 Query: 358 NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK 400 + FV + E A +A+ E N V L V IA+++ Sbjct: 72 ---PRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIARKQ 111 Score = 58.2 bits (139), Expect = 9e-09, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAY 83 + + +LYV ++ L FSP G++ + + A+ Sbjct: 26 RSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM------DPPRNCAF 77 Query: 84 VNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 120 V + E+ +A+ +LN T ++ ++ +++ P L Sbjct: 78 VTYEKMESADQAVAELNGTQVESVQLKVNIARKQPML 114 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 LYV + T + F+ FG I+ S+ + FV YEK E A + Sbjct: 36 PRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM-----DPPRNCAFVTYEKMESADQ 88 Query: 275 AVEALNDSELNGEKLYVGRAQKKN 298 AV LN +++ +L V A+K+ Sbjct: 89 AVAELNGTQVESVQLKVNIARKQP 112 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 8/97 (8%) Query: 110 RIMWSQRDPSLRKKGSGN-IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGF 168 S P R GN +++ D+ L FS FG+I+ ++ D + Sbjct: 23 PFRRSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIID--LSMDP---PRNC 75 Query: 169 GFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRK 205 FV +E+ +A +A+ LNG + ++ V + Sbjct: 76 AFVTYEKMESADQAVAELNGTQVESVQLKVNIARKQP 112 >2CPE-A nrPDB Length = 113 Score = 65.9 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 9/105 (8%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVS--------ASLEKDA-D 255 S + + + +YV+ +N T + + F + G + + D Sbjct: 2 SSGSSGDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 61 Query: 256 GKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNER 300 GK KG V+YE A AVE + + G KL V A+KK Sbjct: 62 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 106 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 9/99 (9%) Query: 311 YRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKS 361 + ++V+ L+DSV + L + F G + K + E GK Sbjct: 5 SSGDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 64 Query: 362 KGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK 400 KG V + P A A+ + + G L V++A++K Sbjct: 65 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 103 Score = 59.7 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 39/102 (38%), Gaps = 9/102 (8%) Query: 118 PSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS--------SKIATDE-NGKSKGF 168 + I+++ L+ + L D F G + I D+ GK KG Sbjct: 8 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 67 Query: 169 GFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQ 210 V +E+ AK A++ +G G ++ V+ + +S Sbjct: 68 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSG 109 Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 9/112 (8%) Query: 24 AATGSESQSVENSSAS-LYVGDLEPSVSEAHLYDIFSPIGSVSS--------IRVCRDAI 74 ++GS E+S S +YV L SV+ L D F G V I + D Sbjct: 1 GSSGSSGDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE 60 Query: 75 TKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 T G A V++ D + A+E + +G ++ +++ P + S Sbjct: 61 TGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSGPSS 112 >6QX9-1A nrPDB Length = 282 Score = 65.5 bits (158), Expect = 6e-11, Method: Composition-based stats. Identities = 48/251 (19%), Positives = 89/251 (35%), Gaps = 40/251 (15%) Query: 323 NLFVKNLDDSVDDEKLEE----EFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 +++ NL++ + ++L++ F+ +G I ++ + + K +G FV F AT A Sbjct: 11 TIYINNLNEKIKKDELKKSLYAIFSQFGQILD--ILVSRSLKMRGQAFVIFKEVSSATNA 68 Query: 379 ITEKNQQIVAGKPLYVAIAQ-----------------RKDVRRSQLAQQIQA-RNQMRYQ 420 + KP+ + A+ RK +R +Q+ A + ++ Sbjct: 69 LRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGG 128 Query: 421 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVPFNGPNPQQMNPM----------GGMPKN 470 AT A +PG MPPM PR + P M P G +P Sbjct: 129 GATPVVGAVQGPVPG--MPPM---TQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPG 183 Query: 471 GMPP-QFRNGPVYGVPPQGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGK 529 MPP Q G + P P N ++ + + L+ + G+ Sbjct: 184 AMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGR 243 Query: 530 ITGMILDLPPQ 540 ++ + Sbjct: 244 HDIAFVEFDNE 254 Score = 59.0 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 6/85 (7%) Query: 125 SGNIFIKNLHPDIDNKAL----YDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 + I+I NL+ I L Y FS FG IL I + K +G FV F+E +A Sbjct: 9 NHTIYINNLNEKIKKDELKKSLYAIFSQFGQILD--ILVSRSLKMRGQAFVIFKEVSSAT 66 Query: 181 EAIDALNGMLLNGQEIYVAPHLSRK 205 A+ ++ G + + + + Sbjct: 67 NALRSMQGFPFYDKPMRIQYAKTDS 91 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 40/98 (40%), Gaps = 8/98 (8%) Query: 37 SASLYVGDLEPSVSEAHL----YDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAG 92 + ++Y+ +L + + L Y IFS G + I V R + G A+V F + + Sbjct: 9 NHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSR---SLKMRGQAFVIFKEVSSA 65 Query: 93 RKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFI 130 A+ + P + RI +++ S F+ Sbjct: 66 TNALRSMQGFPFYDKPMRIQYAK-TDSDIIAKMKGTFV 102 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 39/83 (46%), Gaps = 6/83 (7%) Query: 220 NLYVKNINSETTDEQF----QELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKA 275 +Y+ N+N + ++ +F++FG I+ + + K++G FV +++ A A Sbjct: 11 TIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSR--SLKMRGQAFVIFKEVSSATNA 68 Query: 276 VEALNDSELNGEKLYVGRAQKKN 298 + ++ + + + A+ + Sbjct: 69 LRSMQGFPFYDKPMRIQYAKTDS 91 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 37/110 (33%), Gaps = 6/110 (5%) Query: 188 GMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVS 247 G + G + L E ++ L++ N+ ET + LF +F Sbjct: 178 GQIPPGAMPPQQLMPGQMPPAQPLSENPPNH-ILFLTNLPEETNELMLSMLFNQFPGFKE 236 Query: 248 ASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSEL-NGEKLYVGRAQK 296 L FV ++ A A +AL ++ + + A+K Sbjct: 237 VRLVPGRH----DIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK 282 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 14/99 (14%), Positives = 34/99 (34%), Gaps = 6/99 (6%) Query: 302 HVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKS 361 ++ Q + + LF+ NL + ++ L F + +++ + Sbjct: 189 QLMPGQMPPAQPLSENPPNHI-LFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHD-- 245 Query: 362 KGFGFVCFSTPEEATKAITEKNQ-QIVAGKPLYVAIAQR 399 FV F +A A +I + ++ A++ Sbjct: 246 --IAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK 282 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 31/85 (36%), Gaps = 5/85 (5%) Query: 116 RDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEE 175 P + +F+ NL + + L F+ F ++ + FV F+ Sbjct: 198 AQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHD----IAFVEFDN 253 Query: 176 EGAAKEAIDALNGMLL-NGQEIYVA 199 E A A DAL G + + ++ Sbjct: 254 EVQAGAARDALQGFKITQNNAMKIS 278 >6ID0-O nrPDB Length = 420 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 58/152 (38%), Gaps = 6/152 (3%) Query: 302 HVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKS 361 +LK+ RL+ L+V L D++ + L F +G I + V++ + Sbjct: 212 KLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ--- 268 Query: 362 KGFGFVCFSTPEEAT-KAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQ 420 F+ F+T + A A N+ IV G+ L V + + R + + + ++ + Sbjct: 269 --CAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLE 326 Query: 421 QATAAAAAAAAGMPGQFMPPMFYGVMPPRGVP 452 A + Y +PP G P Sbjct: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPP 358 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 46/125 (36%), Gaps = 6/125 (4%) Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKI 157 +N L R R K +++ L I L + F FG+I + + Sbjct: 204 GINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITV 263 Query: 158 ATDENGKSKGFGFVHFEEEGAAK-EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKA 216 + F+ F AA+ A + N +++NG+ + V S+ R + E+ Sbjct: 264 VQRQQ-----CAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGT 318 Query: 217 HYTNL 221 + + Sbjct: 319 TDSGI 323 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 43/111 (38%), Gaps = 9/111 (8%) Query: 17 IQDDQKQAATGSESQS--VENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAI 74 + D + A+ + + +LYVG L +++E L + F G + +I V Sbjct: 209 VADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV---- 264 Query: 75 TKTSLGYAYVNFNDHEAGR-KAIEQLNYTPIKGRLCRIMWSQRDPSLRKKG 124 A++ F +A A + N + GR + W + + K+ Sbjct: 265 --QRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEK 313 Score = 55.9 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDA-VKAVE 277 T LYV + T+ + F +FG I + ++ + + F+ + + A V A + Sbjct: 232 TTLYVGGLGDTITETDLRNHFYQFGEIRTITVV-----QRQQCAFIQFATRQAAEVAAEK 286 Query: 278 ALNDSELNGEKLYVGRAQ 295 + N +NG +L V + Sbjct: 287 SFNKLIVNGRRLNVKWGR 304 >6QDV-M nrPDB Length = 289 Score = 64.0 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 6/98 (6%) Query: 302 HVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKS 361 +LK+ RL+ L+V L D++ + L F +G I + V++ + Sbjct: 195 KLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ--- 251 Query: 362 KGFGFVCFSTPEEAT-KAITEKNQQIVAGKPLYVAIAQ 398 F+ F+T + A A N+ IV G+ L V + Sbjct: 252 --CAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGR 287 Score = 59.7 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 40/108 (37%), Gaps = 6/108 (5%) Query: 98 QLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKI 157 +N L R R K +++ L I L + F FG+I + + Sbjct: 187 GINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITV 246 Query: 158 ATDENGKSKGFGFVHFEEEGAAK-EAIDALNGMLLNGQEIYVAPHLSR 204 + F+ F AA+ A + N +++NG+ + V S+ Sbjct: 247 VQRQQ-----CAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQ 289 Score = 59.7 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 17 IQDDQKQAATGSESQS--VENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAI 74 + D + A+ + + +LYVG L +++E L + F G + +I V Sbjct: 192 VADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV---- 247 Query: 75 TKTSLGYAYVNFNDHEAGR-KAIEQLNYTPIKGRLCRIMWSQR 116 A++ F +A A + N + GR + W + Sbjct: 248 --QRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRS 288 Score = 56.3 bits (134), Expect = 4e-08, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 49/129 (37%), Gaps = 15/129 (11%) Query: 174 EEEGAAKEAIDALNGMLLNGQEIYVAPHLSRK--ERDSQLEE----TKAHYTNLYVKNIN 227 E+ + + N + + + ++ K +R S + T LYV + Sbjct: 167 EKPTDPDDPLADQN---IKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLG 223 Query: 228 SETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAV-KAVEALNDSELNG 286 T+ + F +FG I + ++ + + F+ + + A A ++ N +NG Sbjct: 224 DTITETDLRNHFYQFGEIRTITVV-----QRQQCAFIQFATRQAAEVAAEKSFNKLIVNG 278 Query: 287 EKLYVGRAQ 295 +L V + Sbjct: 279 RRLNVKWGR 287 >1X5P-A nrPDB Length = 97 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 7/95 (7%) Query: 311 YRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFS 370 E+ A +G L+V + + L F+P+G I + + FV + Sbjct: 5 SSGERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM--DP---PRNCAFVTYE 57 Query: 371 TPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRS 405 E A +A+ E N V L V IA+++ + S Sbjct: 58 KMESADQAVAELNGTQVESVQLKVNIARKQPMLDS 92 Score = 59.0 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 43/104 (41%), Gaps = 9/104 (8%) Query: 24 AATGSESQSVE-NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 ++GS + +LYV ++ L FSP G++ + + A Sbjct: 1 GSSGSSGERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM------DPPRNCA 52 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSG 126 +V + E+ +A+ +LN T ++ ++ +++ P L S Sbjct: 53 FVTYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDSGPSS 96 Score = 58.2 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 7/94 (7%) Query: 205 KERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFV 264 S LYV + T + F+ FG I+ S+ + FV Sbjct: 2 SSGSSGERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM-----DPPRNCAFV 54 Query: 265 NYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 YEK E A +AV LN +++ +L V A+K+ Sbjct: 55 TYEKMESADQAVAELNGTQVESVQLKVNIARKQP 88 Score = 52.4 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 127 NIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 +++ D+ L FS FG+I+ ++ D + FV +E+ +A +A+ L Sbjct: 17 TLYVYG--EDMTPTLLRGAFSPFGNIID--LSMDP---PRNCAFVTYEKMESADQAVAEL 69 Query: 187 NGMLLNGQEIYVAPHLSRKERDSQ 210 NG + ++ V + DS Sbjct: 70 NGTQVESVQLKVNIARKQPMLDSG 93 >2F9J-A nrPDB Length = 125 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 4/97 (4%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAID 184 + + I+NL I + +YD F +G I ++ +++G +V +E+ AK A D Sbjct: 18 NRILMIRNLPYKITAEEMYDIFGKYGPIRQIRVG--NTPETRGTAYVVYEDIFDAKNACD 75 Query: 185 ALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNL 221 L+G + + + V R Q +TK L Sbjct: 76 HLSGFNVCNRYLVV--LYYNANRAFQKMDTKKKEEQL 110 Score = 59.7 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 13/114 (11%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 + L + +L ++ +YDIF G + IRV T G AYV + D + A Sbjct: 18 NRILMIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPET---RGTAYVVYEDIFDAKNAC 74 Query: 97 EQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFG 150 + L+ + R +++ + + +K + + L +G Sbjct: 75 DHLSGFNVCNRYLVVLYYNANRAFQKMDTKK----------KEEQLKLLKEKYG 118 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 13/116 (11%) Query: 204 RKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGF 263 + + + + L ++N+ + T E+ ++F K+GPI + + +G + Sbjct: 4 QAAKRANIRLPPEVNRILMIRNLPYKITAEEMYDIFGKYGPIRQIRVG--NTPETRGTAY 61 Query: 264 VNYEKHEDAVKAVEALNDSELNGEKLYVGR-----------AQKKNERMHVLKKQY 308 V YE DA A + L+ + L V +KK E++ +LK++Y Sbjct: 62 VVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY 117 Score = 55.9 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAIT 380 L ++NL + E++ + F YG I +V +++G +V + +A A Sbjct: 18 NRILMIRNLPYKITAEEMYDIFGKYGPIRQIRV--GNTPETRGTAYVVYEDIFDAKNACD 75 Query: 381 EKNQQIVAGKPLYVAIA------QRKDVRRSQ 406 + V + L V Q+ D ++ + Sbjct: 76 HLSGFNVCNRYLVVLYYNANRAFQKMDTKKKE 107 >6GML-X nrPDB Length = 404 Score = 62.4 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 38/96 (39%), Gaps = 7/96 (7%) Query: 305 KKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGF 364 + E+ A +G L+V + + L F+P+G I + + Sbjct: 269 PFRRSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM--DP---PRNC 321 Query: 365 GFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK 400 FV + E A +A+ E N V L V IA+++ Sbjct: 322 AFVTYEKMESADQAVAELNGTQVESVQLKVNIARKQ 357 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 39/97 (40%), Gaps = 8/97 (8%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAY 83 + + +LYV ++ L FSP G++ + + A+ Sbjct: 272 RSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM------DPPRNCAF 323 Query: 84 VNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 120 V + E+ +A+ +LN T ++ ++ +++ P L Sbjct: 324 VTYEKMESADQAVAELNGTQVESVQLKVNIARKQPML 360 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 LYV + T + F+ FG I+ S+ + FV YEK E A + Sbjct: 282 PRKGNTLYVYG--EDMTPTLLRGAFSPFGNIIDLSM-----DPPRNCAFVTYEKMESADQ 334 Query: 275 AVEALNDSELNGEKLYVGRAQKKN 298 AV LN +++ +L V A+K+ Sbjct: 335 AVAELNGTQVESVQLKVNIARKQP 358 Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 10/120 (8%) Query: 110 RIMWSQRDPSLRKKGSGN-IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGF 168 S P R GN +++ D+ L FS FG+I+ ++ D + Sbjct: 269 PFRRSDSFPERRAPRKGNTLYVYG--EDMTPTLLRGAFSPFGNIID--LSMDP---PRNC 321 Query: 169 GFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINS 228 FV +E+ +A +A+ LNG + ++ V + D+ K+ + +L V+N Sbjct: 322 AFVTYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDAAT--GKSVWGSLAVQNSPK 379 >5OPT-h nrPDB Length = 257 Score = 62.4 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 69/191 (36%), Gaps = 17/191 (8%) Query: 28 SESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFN 87 ++ +S + LYV + S +F G V + YA + F Sbjct: 66 AKQRSDAANHNGLYVKNWGQG-SVDDARALFGTAGKVV-------GVRVRRRRYAIIFFE 117 Query: 88 DHEAGRKAIEQLNYTPIKGRLCRIMWSQRDP-SLRKKGSGNIFIKNLHP-DIDNKALYDT 145 + A +KAI+ N G + ++ ++ P S +F+ + K + + Sbjct: 118 NAAAVKKAIDLFNGKEFMGNVLSVVPAKTTPKPDPHANSSVVFVSPIFRASTTKKQILEL 177 Query: 146 FSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRK 205 FS K+ ++ + +V+ + AA+ A+ NG G+++ VA Sbjct: 178 FSG------MKVLRLRTYRNN-YAYVYLDTPAAAQRAVKEKNGAEFRGKQLRVALSTRSL 230 Query: 206 ERDSQLEETKA 216 +D E Sbjct: 231 AKDRARAERAR 241 Score = 61.7 bits (148), Expect = 8e-10, Method: Composition-based stats. Identities = 49/211 (23%), Positives = 85/211 (40%), Gaps = 33/211 (15%) Query: 207 RDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNY 266 RD++ A++ LYVKN + D+ + LF G +V + + + + + Sbjct: 64 RDAKQRSDAANHNGLYVKNWGQGSVDDA-RALFGTAGKVVGVRVRRRR------YAIIFF 116 Query: 267 EKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFV 326 E KA++ N E G L V A+ + +FV Sbjct: 117 ENAAAVKKAIDLFNGKEFMGNVLSVVPAKTTPK---------------PDPHANSSVVFV 161 Query: 327 KNL-DDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQ 385 + S +++ E F+ KV+R ++ + +V TP A +A+ EKN Sbjct: 162 SPIFRASTTKKQILELFS------GMKVLRLRTYRNN-YAYVYLDTPAAAQRAVKEKNGA 214 Query: 386 IVAGKPLYVAIAQR---KDVRRSQLAQQIQA 413 GK L VA++ R KD R++ A+ + A Sbjct: 215 EFRGKQLRVALSTRSLAKDRARAERARLLMA 245 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 20/156 (12%) Query: 150 GDILSSKIATDENGKSKG-------FGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHL 202 G + ++ GK G + + FE A K+AID NG G + V P Sbjct: 86 GSVDDARALFGTAGKVVGVRVRRRRYAIIFFENAAAVKKAIDLFNGKEFMGNVLSVVPAK 145 Query: 203 SRKERDSQLEETKAHYTNLYVKNINS-ETTDEQFQELFAKFGPIVSASLEKDADGKLKGF 261 + + A+ + ++V I TT +Q ELF+ ++ ++ + Sbjct: 146 TTP-----KPDPHANSSVVFVSPIFRASTTKKQILELFSGM-KVLRLRTYRNN------Y 193 Query: 262 GFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 +V + A +AV+ N +E G++L V + + Sbjct: 194 AYVYLDTPAAAQRAVKEKNGAEFRGKQLRVALSTRS 229 >2LCW-A nrPDB Length = 116 Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 9/89 (10%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKSKGFGFVCFST 371 +FV+ L ++V E + + F G I + K E GK KG V F Sbjct: 7 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 66 Query: 372 PEEATKAITEKNQQIVAGKPLYVAIAQRK 400 P A AI + + +G P+ V+ A R+ Sbjct: 67 PPSAKAAIDWFDGKEFSGNPIKVSFATRR 95 Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Query: 212 EETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVS--------ASLEKDA-DGKLKGFG 262 E+ + ++V+ + T E + F + G I + +L D GKLKG Sbjct: 1 EQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEA 60 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 V+++ A A++ + E +G + V A ++ Sbjct: 61 TVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRR 95 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 41/95 (43%), Gaps = 8/95 (8%) Query: 31 QSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSS--------IRVCRDAITKTSLGYA 82 + + + +++V L +V+ + D F IG + + I + D T G A Sbjct: 1 EQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEA 60 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRD 117 V+F+D + + AI+ + G ++ ++ R Sbjct: 61 TVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRR 95 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 9/88 (10%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILS--------SKIATD-ENGKSKGFGFVHFE 174 + IF++ L ++ +++ D F G I + + TD E GK KG V F+ Sbjct: 6 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 65 Query: 175 EEGAAKEAIDALNGMLLNGQEIYVAPHL 202 + +AK AID +G +G I V+ Sbjct: 66 DPPSAKAAIDWFDGKEFSGNPIKVSFAT 93 >2YTC-A nrPDB Length = 85 Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 7/89 (7%) Query: 28 SESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFN 87 S S + + +LYVG L +++E L + F G + +I V A++ F Sbjct: 3 SGSSGEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV------QRQQCAFIQFA 56 Query: 88 DHEAGR-KAIEQLNYTPIKGRLCRIMWSQ 115 +A A + N + GR + W + Sbjct: 57 TRQAAEVAAEKSFNKLIVNGRRLNVKWGR 85 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEAT-KAIT 380 L+V L D++ + L F +G I + V++ + F+ F+T + A A Sbjct: 13 TTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ-----CAFIQFATRQAAEVAAEK 67 Query: 381 EKNQQIVAGKPLYVAIAQ 398 N+ IV G+ L V + Sbjct: 68 SFNKLIVNGRRLNVKWGR 85 Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 34/82 (41%), Gaps = 6/82 (7%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGA 178 S K +++ L I L + F FG+I + + + F+ F A Sbjct: 6 SGEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ-----CAFIQFATRQA 60 Query: 179 AK-EAIDALNGMLLNGQEIYVA 199 A+ A + N +++NG+ + V Sbjct: 61 AEVAAEKSFNKLIVNGRRLNVK 82 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 207 RDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNY 266 S T LYV + T+ + F +FG I + ++ + + F+ + Sbjct: 1 GSSGSSGEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV-----QRQQCAFIQF 55 Query: 267 EKHEDAV-KAVEALNDSELNGEKLYVGRAQ 295 + A A ++ N +NG +L V + Sbjct: 56 ATRQAAEVAAEKSFNKLIVNGRRLNVKWGR 85 >1I2T-A nrPDB Length = 61 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Query: 505 QRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEASAAYE 564 RQALGE+LY +V A A KITGM+L+L P ++ LL S++ EA Sbjct: 1 HRQALGERLYPRVQAM--QPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELII 58 Query: 565 SF 566 + Sbjct: 59 AH 60 >2MMY-A nrPDB Length = 97 Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKSKGFGFVCFST 371 +FV+ L + V +++ E F G I + K + GK KG V F Sbjct: 7 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD 66 Query: 372 PEEATKAITEKNQQIVAGKPLYVAIAQRK 400 P A AI + + G + V+ A R+ Sbjct: 67 PPSAKAAIDWFDGKEFHGNIIKVSFATRR 95 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 9/94 (9%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVS--------ASLEKDA-DGKLKGFGFVN 265 + ++V+ + + +Q E F + G I + +L D GK KG V+ Sbjct: 4 MSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVS 63 Query: 266 YEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNE 299 ++ A A++ + E +G + V A ++ E Sbjct: 64 FDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 97 Score = 58.2 bits (139), Expect = 9e-09, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 41/93 (44%), Gaps = 8/93 (8%) Query: 35 NSSASLYVGDLEPSVSEAHLYDIFSPIGSVSS--------IRVCRDAITKTSLGYAYVNF 86 + + +++V L VS + + F IG + + I + D T G A V+F Sbjct: 5 SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSF 64 Query: 87 NDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPS 119 +D + + AI+ + G + ++ ++ R P Sbjct: 65 DDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 97 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 9/92 (9%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILS--------SKIATDE-NGKSKGFGFVHFE 174 + IF++ L + + + F G I + + TD+ GK KG V F+ Sbjct: 6 DNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFD 65 Query: 175 EEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 + +AK AID +G +G I V+ R E Sbjct: 66 DPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 97 >3JB9-Y nrPDB Length = 388 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 15/121 (12%) Query: 320 QGVNLFVKNLDDSVD-DEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 Q L+V + + D +E + FA +G I +V+ S+G F+ + A A Sbjct: 172 QNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVL-----NSRGIAFITYLNEANAQFA 226 Query: 379 ITEKNQQIV-AGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQQATAAAAAAAAGMPGQF 437 Q + + L V A S QARNQ R ++ AA A +P QF Sbjct: 227 KEAMAHQSLDHDECLNVRWATTDPNPAS------QARNQRRLEE--RAANAVKKLLPKQF 278 Query: 438 M 438 + Sbjct: 279 L 279 Score = 55.1 bits (131), Expect = 9e-08, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 37/89 (41%), Gaps = 8/89 (8%) Query: 32 SVENSSASLYVGDLEPSVS-EAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHE 90 S + +LYVG + P+ E + F+ G + IRV S G A++ + + Sbjct: 168 SFLRQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVL------NSRGIAFITYLNEA 221 Query: 91 AGRKAIEQLNYTPIK-GRLCRIMWSQRDP 118 + A E + + + + W+ DP Sbjct: 222 NAQFAKEAMAHQSLDHDECLNVRWATTDP 250 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 7/83 (8%) Query: 216 AHYTNLYVKNI-NSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 LYV I ++ +E FA++G I + +G F+ Y +A Sbjct: 171 RQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVL-----NSRGIAFITYLNEANAQF 225 Query: 275 AVEALNDSELN-GEKLYVGRAQK 296 A EA+ L+ E L V A Sbjct: 226 AKEAMAHQSLDHDECLNVRWATT 248 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 44/99 (44%), Gaps = 12/99 (12%) Query: 125 SGNIFIKNLHPDID-NKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAI 183 + +++ + P D + + F+ +GDI ++ S+G F+ + E A+ A Sbjct: 173 NYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVL-----NSRGIAFITYLNEANAQFAK 227 Query: 184 DAL------NGMLLNGQEIYVAPHLSRKERDSQLEETKA 216 +A+ + LN + P+ + + R+ + E +A Sbjct: 228 EAMAHQSLDHDECLNVRWATTDPNPASQARNQRRLEERA 266 >2LA6-A nrPDB Length = 99 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 9/87 (10%) Query: 321 GVNLFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMRTENGKSKGFGFVCFST 371 +FV+ L ++V E + + F G I + K E GK KG V F Sbjct: 13 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 72 Query: 372 PEEATKAITEKNQQIVAGKPLYVAIAQ 398 P A AI + + +G P+ V+ A Sbjct: 73 PPSAKAAIDWFDGKEFSGNPIKVSFAT 99 Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 9/88 (10%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILS--------SKIATD-ENGKSKGFGFVHFE 174 + IF++ L ++ +++ D F G I + + TD E GK KG V F+ Sbjct: 12 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 71 Query: 175 EEGAAKEAIDALNGMLLNGQEIYVAPHL 202 + +AK AID +G +G I V+ Sbjct: 72 DPPSAKAAIDWFDGKEFSGNPIKVSFAT 99 Score = 56.3 bits (134), Expect = 4e-08, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 36/88 (40%), Gaps = 9/88 (10%) Query: 217 HYTNLYVKNINSETTDEQFQELFAKFGPIVS--------ASLEKDA-DGKLKGFGFVNYE 267 ++V+ + T E + F + G I + +L D GKLKG V+++ Sbjct: 12 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 71 Query: 268 KHEDAVKAVEALNDSELNGEKLYVGRAQ 295 A A++ + E +G + V A Sbjct: 72 DPPSAKAAIDWFDGKEFSGNPIKVSFAT 99 Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 38/88 (43%), Gaps = 8/88 (9%) Query: 36 SSASLYVGDLEPSVSEAHLYDIFSPIGSVSS--------IRVCRDAITKTSLGYAYVNFN 87 + +++V L +V+ + D F IG + + I + D T G A V+F+ Sbjct: 12 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 71 Query: 88 DHEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 D + + AI+ + G ++ ++ Sbjct: 72 DPPSAKAAIDWFDGKEFSGNPIKVSFAT 99 >5YVG-X nrPDB Length = 528 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 9/105 (8%) Query: 305 KKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAK---------VMR 355 + + + +FV+ L ++V E + + F G I + K Sbjct: 270 PRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTD 329 Query: 356 TENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK 400 E GK KG V F P A AI + + +G P+ V+ A R+ Sbjct: 330 RETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRR 374 Score = 58.6 bits (140), Expect = 8e-09, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 42/103 (40%), Gaps = 9/103 (8%) Query: 204 RKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVS--------ASLEKDA- 254 + E+ + ++V+ + T E + F + G I + +L D Sbjct: 272 DQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRE 331 Query: 255 DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKK 297 GKLKG V+++ A A++ + E +G + V A ++ Sbjct: 332 TGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRR 374 Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 44/101 (43%), Gaps = 8/101 (7%) Query: 25 ATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSS--------IRVCRDAITK 76 + +S+ + + +++V L +V+ + D F IG + + I + D T Sbjct: 274 GSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETG 333 Query: 77 TSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRD 117 G A V+F+D + + AI+ + G ++ ++ R Sbjct: 334 KLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRR 374 Score = 55.5 bits (132), Expect = 6e-08, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 9/98 (9%) Query: 114 SQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILS--------SKIATD-ENGK 164 S+ D + IF++ L ++ +++ D F G I + + TD E GK Sbjct: 275 SRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGK 334 Query: 165 SKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHL 202 KG V F++ +AK AID +G +G I V+ Sbjct: 335 LKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT 372 >3JB9-k nrPDB Length = 111 Score = 59.4 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 10/100 (10%) Query: 323 NLFVKNLDDSVDDEKLEE----EFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 L+V NL+D ++ L F+ YGT+ ++ + K +G V F P A A Sbjct: 5 TLYVNNLNDKINKNDLRTALYMLFSTYGTVVD--IVALKTPKMRGQAHVVFFDPSAAAIA 62 Query: 379 ITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMR 418 + I GK + + A K S++ ++I A N R Sbjct: 63 MKALKNFIFFGKEMKIQYAHSK----SKIIERIVAENDSR 98 Score = 55.5 bits (132), Expect = 6e-08, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 6/90 (6%) Query: 219 TNLYVKNINSETTDEQFQE----LFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 LYV N+N + + LF+ +G +V K++G V + A Sbjct: 4 NTLYVNNLNDKINKNDLRTALYMLFSTYGTVVDIVAL--KTPKMRGQAHVVFFDPSAAAI 61 Query: 275 AVEALNDSELNGEKLYVGRAQKKNERMHVL 304 A++AL + G+++ + A K++ + + Sbjct: 62 AMKALKNFIFFGKEMKIQYAHSKSKIIERI 91 Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 9/105 (8%) Query: 124 GSGNIFIKNLHPDIDNKALYD----TFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAA 179 +++ NL+ I+ L FS +G ++ I + K +G V F + AA Sbjct: 2 NQNTLYVNNLNDKINKNDLRTALYMLFSTYGTVVD--IVALKTPKMRGQAHVVFFDPSAA 59 Query: 180 KEAIDALNGMLLNGQEIYVAPHLSRK---ERDSQLEETKAHYTNL 221 A+ AL + G+E+ + S+ ER +++ L Sbjct: 60 AIAMKALKNFIFFGKEMKIQYAHSKSKIIERIVAENDSRGPLKRL 104 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 36 SSASLYVGDLEPSVSEAHLYD----IFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEA 91 + +LYV +L +++ L +FS G+V I + T G A+V F D A Sbjct: 2 NQNTLYVNNLNDKINKNDLRTALYMLFSTYGTVVDIVALK---TPKMRGQAHVVFFDPSA 58 Query: 92 GRKAIEQLNYTPIKGRLCRIMWSQRDPSLRK 122 A++ L G+ +I ++ + + Sbjct: 59 AAIAMKALKNFIFFGKEMKIQYAHSKSKIIE 89 >2MKK-A nrPDB Length = 213 Score = 59.0 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 27/176 (15%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTS--LGYAYVNFNDHEAGRK 94 S +++G + ++EA L + F GS+S +D GY Y+ F ++ R Sbjct: 18 SCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVRS 77 Query: 95 AIEQLNYTPI--------------KGRLCR----IMWS------QRDPSLRKKGSGNIFI 130 ++ ++ P+ + C+ I W R PS R S +F+ Sbjct: 78 LLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVFV 137 Query: 131 KNLHPDIDNKALYDTFSV-FGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDA 185 LH ++ +AL + FG ++ + I TD++ G G V F + + +A+ A Sbjct: 138 GALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSA 193 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 36/178 (20%), Positives = 63/178 (35%), Gaps = 26/178 (14%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGK-----SKGFGFVHFE---EE 176 S +F+ + DI L +TF VFG + D GK KG+ ++ FE Sbjct: 18 SCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKD--GKHPRCPPKGYVYLVFELEKSV 75 Query: 177 GAAKEAIDA--------------LNGMLLNGQEIYVAP-HLSRKERDSQLEETKAHYTNL 221 + +A ++ + +E+ V P L+ + + Sbjct: 76 RSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTV 135 Query: 222 YVKNINSETTDEQFQELFAK-FGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 +V ++ E + FG +V A ++ D G G V + +KAV A Sbjct: 136 FVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSA 193 Score = 48.6 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 65/183 (35%), Gaps = 16/183 (8%) Query: 213 ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGK-----LKGFGFVNYE 267 + + +++ + + T+ F FG + S DGK KG+ ++ +E Sbjct: 13 KNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSL-SVEWP-GKDGKHPRCPPKGYVYLVFE 70 Query: 268 KHEDAVKAVEA-----LNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQ-- 320 + ++A L+ L+ + + + + + V+ + + Sbjct: 71 LEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLD 130 Query: 321 -GVNLFVKNLDDSVDDEKLEEEFAP-YGTITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 +FV L ++ E L +G + A + ++ G G V F+ KA Sbjct: 131 PSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKA 190 Query: 379 ITE 381 ++ Sbjct: 191 VSA 193 >2CQH-A nrPDB Length = 93 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 + LY+ N++ T + ++LF ++ + + G+ FV+Y A++ Sbjct: 5 SSGMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKS-----GYAFVDYPDQNWAIR 59 Query: 275 AVEALNDS-ELNGEKLYVGRAQKKNERM 301 A+E L+ EL+G+ + V + K R Sbjct: 60 AIETLSGKVELHGKIMEVDYSVSKKLRS 87 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 6/93 (6%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGA 178 S G ++I NL P + L F L+ ++ G+ FV + ++ Sbjct: 2 SSGSSGMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKS-----GYAFVDYPDQNW 56 Query: 179 AKEAIDALNG-MLLNGQEIYVAPHLSRKERDSQ 210 A AI+ L+G + L+G+ + V +S+K R S Sbjct: 57 AIRAIETLSGKVELHGKIMEVDYSVSKKLRSSG 89 Score = 55.1 bits (131), Expect = 8e-08, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEK 382 L++ NL +V + L + F + +V+ G+ FV + A +AI Sbjct: 10 KLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKS-----GYAFVDYPDQNWAIRAIETL 64 Query: 383 NQQI-VAGKPLYVAIAQRKDVRRS 405 + ++ + GK + V + K +R S Sbjct: 65 SGKVELHGKIMEVDYSVSKKLRSS 88 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 36/82 (43%), Gaps = 7/82 (8%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 LY+G+L P+V+ L +F ++ GYA+V++ D +AIE Sbjct: 9 NKLYIGNLSPAVTADDLRQLFG------DRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIE 62 Query: 98 QLNYT-PIKGRLCRIMWSQRDP 118 L+ + G++ + +S Sbjct: 63 TLSGKVELHGKIMEVDYSVSKK 84 >5OSG-h nrPDB Length = 235 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 19/159 (11%) Query: 144 DTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLS 203 + FS G ++ ++ + V FE A K+AID N + GQ + V P Sbjct: 72 NVFSAAGKVVKVQLRRQR------YALVFFENSAAVKKAIDLFNEKEVLGQTVLVVPA-- 123 Query: 204 RKERDSQLEETKAHYTNLYVKNI-NSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFG 262 + S + + + ++V I TT Q ELFA + + + + F Sbjct: 124 ---KASPKPDAHENSSCVFVSPIFRPSTTKAQVMELFAGV-KVQRLRMYR------QNFA 173 Query: 263 FVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERM 301 + + A K VE N + G L V + + E++ Sbjct: 174 YAYLDSPAAAKKFVEEKNGTAFRGHTLRVALSARSLEKL 212 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 65/160 (40%), Gaps = 16/160 (10%) Query: 56 DIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQ 115 ++FS G V +++ R YA V F + A +KAI+ N + G+ ++ ++ Sbjct: 72 NVFSAAGKVVKVQLRR-------QRYALVFFENSAAVKKAIDLFNEKEVLGQTVLVVPAK 124 Query: 116 RDP-SLRKKGSGNIFIKNL-HPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHF 173 P + S +F+ + P + + F+ + ++ + F + + Sbjct: 125 ASPKPDAHENSSCVFVSPIFRPSTTKAQVMELFAGV-KVQRLRMYR------QNFAYAYL 177 Query: 174 EEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEE 213 + AAK+ ++ NG G + VA E+ +E Sbjct: 178 DSPAAAKKFVEEKNGTAFRGHTLRVALSARSLEKLRARQE 217 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 59/164 (35%), Gaps = 29/164 (17%) Query: 237 ELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQK 296 +F+ G +V L + + V +E KA++ N+ E+ G+ + V A+ Sbjct: 72 NVFSAAGKVVKVQLRRQR------YALVFFENSAAVKKAIDLFNEKEVLGQTVLVVPAKA 125 Query: 297 KNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNL-DDSVDDEKLEEEFAPYGTITSAKVMR 355 + A +FV + S ++ E FA KV R Sbjct: 126 SPK---------------PDAHENSSCVFVSPIFRPSTTKAQVMELFA------GVKVQR 164 Query: 356 TENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQR 399 + F + +P A K + EKN G L VA++ R Sbjct: 165 LRMYRQN-FAYAYLDSPAAAKKFVEEKNGTAFRGHTLRVALSAR 207 >2RT3-A nrPDB Length = 97 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 5/66 (7%) Query: 121 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 180 + N+F+ NL I + + FG I KI T+ N FVHF AA Sbjct: 14 QSGACRNVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERN-----IAFVHFLNIAAAI 68 Query: 181 EAIDAL 186 +A+ L Sbjct: 69 KAVQEL 74 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 13/79 (16%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITE 381 N+F+ NL + + ++++ E+ P+G I K++ N FV F A KA+ E Sbjct: 19 RNVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERN-----IAFVHFLNIAAAIKAVQE 73 Query: 382 KNQQIVAGKPLYVAIAQRK 400 PL ++R+ Sbjct: 74 L--------PLNPKWSKRR 84 Score = 52.4 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 N+++ N+ + T+++ +E FGPI + + + FV++ A+KAV+ Sbjct: 19 RNVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERN-----IAFVHFLNIAAAIKAVQE 73 Query: 279 L 279 L Sbjct: 74 L 74 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 34/71 (47%), Gaps = 6/71 (8%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 ++++G+L ++E + + P G + I++ T A+V+F + A KA++ Sbjct: 19 RNVFLGNLPNGITEDEIREDLEPFGPIDQIKIV------TERNIAFVHFLNIAAAIKAVQ 72 Query: 98 QLNYTPIKGRL 108 +L P + Sbjct: 73 ELPLNPKWSKR 83 >2XNQ-A nrPDB Length = 97 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 8/81 (9%) Query: 313 LEKMAKYQGVNLFVKNLD-DSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFST 371 L + LF+ NL +V E L F+PYG I + FGF+ F Sbjct: 14 LVPRGSHMKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-------KNAFGFIQFDN 66 Query: 372 PEEATKAITEKNQQIVAGKPL 392 P+ AI ++Q++ GK L Sbjct: 67 PQSVRDAIECESQEMNFGKKL 87 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 8/60 (13%) Query: 126 GNIFIKNLH-PDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAID 184 +FI NL ++ + L+ FS +G I+ I FGF+ F+ + ++AI+ Sbjct: 23 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-------KNAFGFIQFDNPQSVRDAIE 75 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 9/62 (14%) Query: 37 SASLYVGDLE-PSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 + L++G+L +VS+ L+ IFSP G + I + + ++ F++ ++ R A Sbjct: 22 KSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI--------KNAFGFIQFDNPQSVRDA 73 Query: 96 IE 97 IE Sbjct: 74 IE 75 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 219 TNLYVKNIN-SETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVE 277 + L++ N+ + E +F+ +G I+ ++ FGF+ ++ + A+E Sbjct: 23 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-------KNAFGFIQFDNPQSVRDAIE 75 Query: 278 ALNDSELNGEKL 289 + G+KL Sbjct: 76 CESQEMNFGKKL 87 >5WSG-X nrPDB Length = 111 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 7/111 (6%) Query: 195 EIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQE----LFAKFGPIVSASL 250 + R + E LYV +N + ++ + LFA FG ++ S+ Sbjct: 4 PARKKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSM 63 Query: 251 EKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERM 301 K +G F+ + A A +LN G+ L V ++ + + + Sbjct: 64 NFK---KQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFSKSETKTL 111 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 36/104 (34%), Gaps = 9/104 (8%) Query: 107 RLCRIMWSQRDPSLRKKGSGN--IFIKNLHPDIDNKALYD----TFSVFGDILSSKIATD 160 + RI +++ L+ I+ + L F+ FG++L + Sbjct: 7 KKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFK 66 Query: 161 ENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSR 204 K +G F+ A A +LNG G+ + V S Sbjct: 67 ---KQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFSKSE 107 Score = 48.6 bits (114), Expect = 8e-06, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 323 NLFVKNLDDSVDDEKLEE----EFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 L+V L++ ++ ++L FA +G + + K +G F+ T ++A+ A Sbjct: 29 TLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFK---KQRGQAFITMRTIDQASLA 85 Query: 379 ITEKNQQIVAGKPLYVAIAQ 398 N + GKPL V ++ Sbjct: 86 QISLNGERFFGKPLKVEFSK 105 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 34/90 (37%), Gaps = 8/90 (8%) Query: 31 QSVENSSASLYVGDLEPSVSEAHLYD----IFSPIGSVSSIRVCRDAITKTSLGYAYVNF 86 + V + +LYV L ++ L +F+ G V + + K G A++ Sbjct: 21 EPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSM----NFKKQRGQAFITM 76 Query: 87 NDHEAGRKAIEQLNYTPIKGRLCRIMWSQR 116 + A LN G+ ++ +S+ Sbjct: 77 RTIDQASLAQISLNGERFFGKPLKVEFSKS 106 >2M2B-A nrPDB Length = 131 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 51/110 (46%), Gaps = 5/110 (4%) Query: 23 QAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVS--SIRVCRDAITKTSLG 80 QA + S EN++ ++ + +L P + + +P +S ++RV +D T+ + G Sbjct: 9 QALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRG 68 Query: 81 YAYVNFNDHEAGRKA--IEQLNYT-PIKGRLCRIMWSQRDPSLRKKGSGN 127 +A++ + EA + ++ L+ I G+ + +++ G+ Sbjct: 69 FAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGS 118 Score = 48.6 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 49/114 (42%), Gaps = 6/114 (5%) Query: 114 SQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDIL--SSKIATDE-NGKSKGFGF 170 SQ + + I ++NL+P ++ + + + + ++ D+ ++GF F Sbjct: 12 SQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAF 71 Query: 171 VHFEEEGAAK--EAIDALN-GMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNL 221 + AA+ + + AL+ + ++G+ I V K + E ++ ++ Sbjct: 72 IQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASV 125 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 57/134 (42%), Gaps = 13/134 (9%) Query: 303 VLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITS--AKVMRTE-NG 359 VL Q + E ++ + ++NL+ + + APY ++S +V++ + Sbjct: 5 VLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQ 64 Query: 360 KSKGFGFVCFSTPEEAT--KAITEKN-QQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQ 416 ++GF F+ ST E A + + + + GK + V A K +R + + Sbjct: 65 LNRGFAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFA--KGSKRDMASNE-----G 117 Query: 417 MRYQQATAAAAAAA 430 R A+ A+ A A Sbjct: 118 SRISAASVASTAIA 131 Score = 38.2 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 43/109 (39%), Gaps = 10/109 (9%) Query: 199 APHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIV--SASLEKDA-D 255 + LS+ S + ++N+N +T + A + + + + KD Sbjct: 8 SQALSQGSEPSSENAND----TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQT 63 Query: 256 GKLKGFGFVNYEKHEDAV--KAVEALN-DSELNGEKLYVGRAQKKNERM 301 +GF F+ E A + ++AL+ ++G+ + V A+ M Sbjct: 64 QLNRGFAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDM 112 >2LKZ-A nrPDB Length = 95 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 39 SLYVGDLEPSVSEAHLYDIFSPIG--SVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 ++ + ++ P + SP +V++IR+ +D T+ + G+A+V + + + Sbjct: 11 TIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLL 70 Query: 97 EQLNY----TPIKGRLCRIMWSQR 116 + L I G+ + +++ Sbjct: 71 QILQSLHPPLKIDGKTIGVDFAKS 94 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 35/83 (42%), Gaps = 7/83 (8%) Query: 220 NLYVKNINSETTDEQFQELFAKFGP--IVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAV 276 + ++NI T + + + + + L KD + +GF FV DA + + Sbjct: 11 TIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLL 70 Query: 277 EALN----DSELNGEKLYVGRAQ 295 + L +++G+ + V A+ Sbjct: 71 QILQSLHPPLKIDGKTIGVDFAK 93 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 35/87 (40%), Gaps = 7/87 (8%) Query: 125 SGNIFIKNLHPDIDNKALYDTFSVFGD--ILSSKIATDE-NGKSKGFGFVHFEEEGAAKE 181 I ++N+ P ++ S + + + ++ D+ +++GF FV A + Sbjct: 9 MDTIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQ 68 Query: 182 AIDALN----GMLLNGQEIYVAPHLSR 204 + L + ++G+ I V S Sbjct: 69 LLQILQSLHPPLKIDGKTIGVDFAKSA 95 Score = 38.5 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 323 NLFVKNLDDSVDDEKLEEEFAPYGT--ITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAI 379 + ++N+ + + +PY + + + ++++ + +++GF FV S+ +A++ + Sbjct: 11 TIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLL 70 Query: 380 TEKNQ----QIVAGKPLYVAIAQ 398 + GK + V A+ Sbjct: 71 QILQSLHPPLKIDGKTIGVDFAK 93 >2KVI-A nrPDB Length = 96 Score = 52.4 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 312 RLEKMAKYQGVNLFVKNLD-DSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFS 370 E LF+ NL +V E L F+PYG I + FGF+ F Sbjct: 1 MTEMHNIPPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-------KNAFGFIQFD 53 Query: 371 TPEEATKAITEKNQQIVAGKPL 392 P+ AI ++Q++ GK L Sbjct: 54 NPQSVRDAIECESQEMNFGKKL 75 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 10/93 (10%) Query: 126 GNIFIKNLH-PDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAID 184 +FI NL ++ + L+ FS +G I+ I FGF+ F+ + ++AI+ Sbjct: 11 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-------KNAFGFIQFDNPQSVRDAIE 63 Query: 185 ALNGMLLNGQE--IYVAPHLSRKERDSQLEETK 215 + + G++ + V+ +R + D T Sbjct: 64 CESQEMNFGKKLILEVSSSNARPQFDHGDHGTN 96 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 9/62 (14%) Query: 37 SASLYVGDLE-PSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKA 95 + L++G+L +VS+ L+ IFSP G + I + + ++ F++ ++ R A Sbjct: 10 KSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI--------KNAFGFIQFDNPQSVRDA 61 Query: 96 IE 97 IE Sbjct: 62 IE 63 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 37/87 (42%), Gaps = 10/87 (11%) Query: 219 TNLYVKNIN-SETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVE 277 + L++ N+ + E +F+ +G I+ ++ FGF+ ++ + A+E Sbjct: 11 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI-------KNAFGFIQFDNPQSVRDAIE 63 Query: 278 ALNDSELNGEK--LYVGRAQKKNERMH 302 + G+K L V + + + H Sbjct: 64 CESQEMNFGKKLILEVSSSNARPQFDH 90 >6FYY-p nrPDB Length = 763 Score = 52.4 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 42/114 (36%), Gaps = 9/114 (7%) Query: 4 ITDKTAEQLENLNIQDDQKQAATGSESQSVE---NSSASLYVGDLE--PS----VSEAHL 54 +T +T E ++ +I D + E V N + V PS V + L Sbjct: 40 MTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKAL 99 Query: 55 YDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRL 108 +FS G V ++ D T + G+ +V +K I+ + + + Sbjct: 100 TSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKH 153 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 6/109 (5%) Query: 235 FQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGR 293 LF+K G +V+ D GK KGF FV DA K +++ + L+ + Sbjct: 99 LTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLY 158 Query: 294 AQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEF 342 K V + + + E + +L + D+K+ ++F Sbjct: 159 TMK-----DVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQF 202 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 65/162 (40%), Gaps = 23/162 (14%) Query: 84 VNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALY 143 ++F+D E K E+ N + + + PS + + KAL Sbjct: 58 IDFSDLEEQYKVTEEFN----FDQYIVVNGAPVIPSAKVP-------------VLKKALT 100 Query: 144 DTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQE---IYVA 199 FS G +++ + DE GK+KGF FV AK+ I + +G L+ + +Y Sbjct: 101 SLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTM 160 Query: 200 PHLSRKERDSQLEETKAHYTNLYV--KNINSETTDEQFQELF 239 + R D E + +V ++ S D++ ++ F Sbjct: 161 KDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQF 202 Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Query: 336 EKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYV 394 + L F+ G + + + + GK+KGF FV + +A K I + + + K + Sbjct: 97 KALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKH-RL 155 Query: 395 AIAQRKDVRR 404 + KDV R Sbjct: 156 FLYTMKDVER 165 >3N9U-C nrPDB Length = 156 Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 35/99 (35%), Gaps = 2/99 (2%) Query: 31 QSVENSSASLYVGDLEPSVSEAHLYDIFSPIG--SVSSIRVCRDAITKTSLGYAYVNFND 88 + N A++YVG ++ L + IG V ++ + S GYA V Sbjct: 49 SGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVAS 108 Query: 89 HEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGN 127 + K +E L + G + + R + + Sbjct: 109 ENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQAR 147 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 49/135 (36%), Gaps = 17/135 (12%) Query: 299 ERMHVLKKQYEAYRLEKMAKY------------QGVNLFVKNLDDSVDDEKLEEEFAPYG 346 + M + + K + ++V + D++L + G Sbjct: 21 QSMEPPPPVRQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIG 80 Query: 347 --TITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVR 403 + K NG+SKG+ V ++ K + +++ G+ + V A R+++ Sbjct: 81 VYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNL- 139 Query: 404 RSQLAQQIQARNQMR 418 SQ Q + R +R Sbjct: 140 -SQFEAQARKRECVR 153 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 45/108 (41%), Gaps = 3/108 (2%) Query: 117 DPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFG--DILSSKIATDE-NGKSKGFGFVHF 173 S + +++ + ++ L G D++ K A + NG+SKG+ V Sbjct: 47 TYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVV 106 Query: 174 EEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNL 221 E + + ++ L G +LNG+++ V P + + + K + Sbjct: 107 ASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV 154 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFG--PIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 +YV + + TTD+Q ++ G +V ++ +G+ KG+ V K +E Sbjct: 58 VYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLE 117 Query: 278 ALNDSELNGEKLYVGRAQKKN 298 L LNGEK+ V A ++N Sbjct: 118 LLPGKVLNGEKVDVRPATRQN 138 >2LXI-A nrPDB Length = 91 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 45 LEPSVSEAHLYDIFSPIGS-VSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE-QLNYT 102 L + +E + G +R+ R+ + S G+A+V F+ + + +E + Sbjct: 9 LPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSL 68 Query: 103 PIKGRLCRIMWSQRDPSLRK 122 I G+ + +S P + + Sbjct: 69 NILGQKVSMHYSDPKPKINE 88 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 38/86 (44%), Gaps = 5/86 (5%) Query: 218 YTNLYVKNINSETTDEQFQELFAKFG-PIVSASLEKDAD-GKLKGFGFVNYEKHEDAVKA 275 + ++ + T++ + G L ++ G+ +GF FV + +DA + Sbjct: 1 SNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRW 60 Query: 276 VEALNDSELN--GEKLYVGRAQKKNE 299 +EA N LN G+K+ + + K + Sbjct: 61 MEA-NQHSLNILGQKVSMHYSDPKPK 85 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 128 IFIKNLHPDIDNKALYDTFSVFG-DILSSKIATDEN-GKSKGFGFVHFEEEGAAKEAID- 184 + ++ L + G ++ +++ G+S+GF FV F A ++ Sbjct: 4 VMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEA 63 Query: 185 ALNGMLLNGQEIYVAPHLSRKERDSQLEET 214 + + + GQ V+ H S + E+ Sbjct: 64 NQHSLNILGQ--KVSMHYSD-PKPKINEDW 90 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 42/80 (52%), Gaps = 3/80 (3%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYG-TITSAKVMRTEN-GKSKGFGFVCFSTPEEATKAITE 381 + ++ L + ++ + + +G ++MR ++ G+S+GF FV FS ++AT+ + Sbjct: 4 VMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEA 63 Query: 382 -KNQQIVAGKPLYVAIAQRK 400 ++ + G+ + + + K Sbjct: 64 NQHSLNILGQKVSMHYSDPK 83 >5MDU-A nrPDB Length = 157 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 36/99 (36%), Gaps = 6/99 (6%) Query: 19 DDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTS 78 + + S++ S +L++G + SV E L +F GSV S+ + + Sbjct: 4 TRRFERDPTIPPDSIKVYSRTLFLGGITRSVREPVLRSMFERFGSVQSLIL------NHN 57 Query: 79 LGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRD 117 + ++ +A KA + P R W Sbjct: 58 YRHGFLKMFRRDAAEKAQVAMENVPFADTTIRTKWGVGF 96 Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 31/91 (34%), Gaps = 5/91 (5%) Query: 118 PSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEG 177 P K S +F+ + + L F FG + S + + GF+ Sbjct: 15 PDSIKVYSRTLFLGGITRSVREPVLRSMFERFGSVQSLILNHNYR-----HGFLKMFRRD 69 Query: 178 AAKEAIDALNGMLLNGQEIYVAPHLSRKERD 208 AA++A A+ + I + R+ Sbjct: 70 AAEKAQVAMENVPFADTTIRTKWGVGFGPRE 100 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 28/79 (35%), Gaps = 5/79 (6%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 K LF+ + SV + L F +G++ S ++ N + GF+ + A K Sbjct: 19 KVYSRTLFLGGITRSVREPVLRSMFERFGSVQS--LILNHNYRH---GFLKMFRRDAAEK 73 Query: 378 AITEKNQQIVAGKPLYVAI 396 A A + Sbjct: 74 AQVAMENVPFADTTIRTKW 92 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 29/81 (35%), Gaps = 5/81 (6%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVK 274 K + L++ I + + +F +FG + S L + GF+ + + A K Sbjct: 19 KVYSRTLFLGGITRSVREPVLRSMFERFGSVQSLILNHNYR-----HGFLKMFRRDAAEK 73 Query: 275 AVEALNDSELNGEKLYVGRAQ 295 A A+ + + Sbjct: 74 AQVAMENVPFADTTIRTKWGV 94 >6D6V-H nrPDB Length = 542 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 27 GSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNF 86 E + +LY+ L P S+ L IF + +I + ++ G+A++ F Sbjct: 236 NLEQALKNSKQRTLYIDFLPPKCSKQTLVSIFGNF-RIININLPLQKNSQLCQGFAFIEF 294 Query: 87 NDHEAGRKAIEQLN 100 E +A+ N Sbjct: 295 FSEEEANQALITKN 308 Score = 45.5 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 36/96 (37%), Gaps = 5/96 (5%) Query: 101 YTPIKGRLCRIMWSQRDP---SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKI 157 +K ++ +L+ ++I L P + L F F I++ + Sbjct: 219 ILKVKMDSLKVKRRFPFNLEQALKNSKQRTLYIDFLPPKCSKQTLVSIFGNF-RIININL 277 Query: 158 ATDENGK-SKGFGFVHFEEEGAAKEAIDALNGMLLN 192 +N + +GF F+ F E A +A+ N + Sbjct: 278 PLQKNSQLCQGFAFIEFFSEEEANQALITKNSSIPK 313 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 215 KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGK-LKGFGFVNYEKHEDAV 273 + LY+ + + + + +F F I++ +L + + +GF F+ + E+A Sbjct: 243 NSKQRTLYIDFLPPKCSKQTLVSIFGNF-RIININLPLQKNSQLCQGFAFIEFFSEEEAN 301 Query: 274 KAVEALN 280 +A+ N Sbjct: 302 QALITKN 308 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 319 YQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGK-SKGFGFVCFSTPEEATK 377 + L++ L + L F + I + + +N + +GF F+ F + EEA + Sbjct: 244 SKQRTLYIDFLPPKCSKQTLVSIFGNF-RIININLPLQKNSQLCQGFAFIEFFSEEEANQ 302 Query: 378 AITEKNQQIVA 388 A+ KN I Sbjct: 303 ALITKNSSIPK 313 >3NS5-A nrPDB Length = 91 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 23/58 (39%) Query: 51 EAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRL 108 + L +FS G V ++ D T + G+ +V +K I+ + + + Sbjct: 26 KKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKH 83 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 233 EQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVEALNDSELN 285 + LF+K G +V+ D GK KGF FV DA K +++ + L+ Sbjct: 27 KALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLD 80 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 140 KALYDTFSVFGDILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQE 195 KAL FS G +++ + DE GK+KGF FV AK+ I + +G L+ + Sbjct: 27 KALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKH 83 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 336 EKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVA 388 + L F+ G + + + + GK+KGF FV + +A K I + + + Sbjct: 27 KALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLD 80 >2RUG-A nrPDB Length = 114 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 5/64 (7%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKS----KGFGFVHFEEEGAAKE 181 +F+ L PDID + +F FG ++ KS KG+ F+ F+EE + + Sbjct: 9 RKVFVGGLPPDIDEDEITASFRRFGPLV-VDWPHKAESKSYFPPKGYAFLLFQEESSVQA 67 Query: 182 AIDA 185 IDA Sbjct: 68 LIDA 71 Score = 45.9 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 29/64 (45%), Gaps = 5/64 (7%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKL----KGFGFVNYEKHEDAVK 274 ++V + + +++ F +FGP+V A+ K KG+ F+ +++ Sbjct: 9 RKVFVGGLPPDIDEDEITASFRRFGPLV-VDWPHKAESKSYFPPKGYAFLLFQEESSVQA 67 Query: 275 AVEA 278 ++A Sbjct: 68 LIDA 71 Score = 45.5 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITK---TSLGYAYVNFNDHEAGRK 94 ++VG L P + E + F G + + A +K GYA++ F + + + Sbjct: 9 RKVFVGGLPPDIDEDEITASFRRFGPLV-VDWPHKAESKSYFPPKGYAFLLFQEESSVQA 67 Query: 95 AIEQ 98 I+ Sbjct: 68 LIDA 71 Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 23/64 (35%), Gaps = 5/64 (7%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKS----KGFGFVCFSTPEEATK 377 +FV L +D++++ F +G + KS KG+ F+ F Sbjct: 9 RKVFVGGLPPDIDEDEITASFRRFGPLV-VDWPHKAESKSYFPPKGYAFLLFQEESSVQA 67 Query: 378 AITE 381 I Sbjct: 68 LIDA 71 >3P6Y-C nrPDB Length = 90 Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 30/70 (42%), Gaps = 2/70 (2%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIG--SVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 LY+G+L ++ L + +G + I+ + S G+A V + +K ++ Sbjct: 4 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 63 Query: 98 QLNYTPIKGR 107 L + G+ Sbjct: 64 LLPKRELHGQ 73 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Query: 128 IFIKNLHPDIDNKALYDTFSVFG--DILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 ++I NL ++ L + G DIL K + NG+SKGF V E ++K+ +D Sbjct: 4 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 63 Query: 185 ALNGMLLNGQEIYVAPH 201 L L+GQ V P Sbjct: 64 LLPKRELHGQNPVVTPS 80 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFG--PIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 LY+ N+ TTDE E G I+ ++ +G+ KGF V + K ++ Sbjct: 4 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 63 Query: 278 ALNDSELNGEKLYVGRAQK 296 L EL+G+ V + K Sbjct: 64 LLPKRELHGQNPVVTPSNK 82 Score = 37.8 bits (86), Expect = 0.015, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 3/79 (3%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYG--TITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 L++ NL DE L E G I K NG+SKGF V + + K + Sbjct: 4 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 63 Query: 381 EKNQQIVAGKPLYVAIAQR 399 ++ + G+ V + + Sbjct: 64 LLPKRELHGQNPVVTPSNK 82 >5WU6-A nrPDB Length = 485 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 6/111 (5%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITE 381 ++FV VD +L E F +G + S VM + G F V A +A+ Sbjct: 4 RSVFVSGFPRDVDSAQLSEYFLAFGPVASV-VMDKDKGV---FAIVEMGD-VGAREAVLS 58 Query: 382 KNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMRYQQATAAAAAAAAG 432 ++Q + G L V ++K+ +S ++ + +Q A A A AA G Sbjct: 59 QSQHSLGGHRLRVRPREQKEF-QSPASKSPKGAAPDSHQLAKALAEAADVG 108 Score = 48.2 bits (113), Expect = 9e-06, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 7/78 (8%) Query: 124 GSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKG-FGFVHFEEEGAAKEA 182 G ++F+ D+D+ L + F FG + + + D++ KG F V + G A+EA Sbjct: 2 GLRSVFVSGFPRDVDSAQLSEYFLAFGPV--ASVVMDKD---KGVFAIVEMGDVG-AREA 55 Query: 183 IDALNGMLLNGQEIYVAP 200 + + + L G + V P Sbjct: 56 VLSQSQHSLGGHRLRVRP 73 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 32/81 (39%), Gaps = 6/81 (7%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 S++V V A L + F G V+S+ + +D +A V D R+A+ Sbjct: 4 RSVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKDKGV-----FAIVEMGDVG-AREAVL 57 Query: 98 QLNYTPIKGRLCRIMWSQRDP 118 + + G R+ ++ Sbjct: 58 SQSQHSLGGHRLRVRPREQKE 78 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 8/102 (7%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKG-FGFVNYEKHEDAVKAVE 277 +++V + Q E F FGP+ S ++KD KG F V A +AV Sbjct: 4 RSVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKD-----KGVFAIVEMGDVG-AREAVL 57 Query: 278 ALNDSELNGEKLYVGRAQKKNERMHVLK-KQYEAYRLEKMAK 318 + + L G +L V ++K + K + A ++AK Sbjct: 58 SQSQHSLGGHRLRVRPREQKEFQSPASKSPKGAAPDSHQLAK 99 >2CPI-A nrPDB Length = 111 Score = 49.3 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 7/84 (8%) Query: 221 LYVKNINSETTDEQFQ---ELFAKFGPIVSASLEKDAD-GKLKG---FGFVNYEKHEDAV 273 ++V ++ D + E F KFG I + +G +V Y + EDA+ Sbjct: 18 VFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDAL 77 Query: 274 KAVEALNDSELNGEKLYVGRAQKK 297 +A++ +N+ ++G L K Sbjct: 78 RAIQCVNNVVVDGRTLKASLGTTK 101 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 31/89 (34%), Gaps = 6/89 (6%) Query: 36 SSASLYVGDLEPSVSEAHLY---DIFSPIGSVSSIRVCRDAITKTSLG---YAYVNFNDH 89 ++V L +++ + + F G + + + S G AYV + Sbjct: 14 QKNLVFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRS 73 Query: 90 EAGRKAIEQLNYTPIKGRLCRIMWSQRDP 118 E +AI+ +N + GR + Sbjct: 74 EDALRAIQCVNNVVVDGRTLKASLGTTKY 102 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 9/90 (10%) Query: 319 YQGVNLFVKNLDDSVDDEKL---EEEFAPYGTITSAKVMRTENGK--SKG---FGFVCFS 370 Q +FV L + D ++ E F +G I V+ S+G +V + Sbjct: 13 VQKNLVFVVGLSQRLADPEVLKRPEYFGKFGKIHKV-VINNSTSYAGSQGPSASAYVTYI 71 Query: 371 TPEEATKAITEKNQQIVAGKPLYVAIAQRK 400 E+A +AI N +V G+ L ++ K Sbjct: 72 RSEDALRAIQCVNNVVVDGRTLKASLGTTK 101 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Query: 128 IFIKNLHPDIDNKALY---DTFSVFGDILSSKIATDENGK--SKG---FGFVHFEEEGAA 179 +F+ L + + + + F FG I + + S+G +V + A Sbjct: 18 VFVVGLSQRLADPEVLKRPEYFGKFGKIHKV-VINNSTSYAGSQGPSASAYVTYIRSEDA 76 Query: 180 KEAIDALNGMLLNGQEIYVA 199 AI +N ++++G+ + + Sbjct: 77 LRAIQCVNNVVVDGRTLKAS 96 >3Q2T-C nrPDB Length = 229 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 30/70 (42%), Gaps = 2/70 (2%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIG--SVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 LY+G+L ++ L + +G + I+ + S G+A V + +K ++ Sbjct: 71 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 130 Query: 98 QLNYTPIKGR 107 L + G+ Sbjct: 131 LLPKRELHGQ 140 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Query: 128 IFIKNLHPDIDNKALYDTFSVFG--DILSSKIATDE-NGKSKGFGFVHFEEEGAAKEAID 184 ++I NL ++ L + G DIL K + NG+SKGF V E ++K+ +D Sbjct: 71 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 130 Query: 185 ALNGMLLNGQEIYVAP 200 L L+GQ V P Sbjct: 131 LLPKRELHGQNPVVTP 146 Score = 38.5 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 12/116 (10%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYG--TITSAKVMRTE-NGKSKGFGFVCFSTPEEATKAIT 380 L++ NL DE L E G I K NG+SKGF V + + K + Sbjct: 71 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 130 Query: 381 EKNQQIVAGKPLYVAIAQRKDVRRSQLAQ-QIQARNQMRYQQATAAAAAAAAGMPG 435 ++ + G+ V V + L+Q ++Q+R + Q+ + AG PG Sbjct: 131 LLPKRELHGQNPVVTP-----VNKQFLSQFEMQSR---KTTQSGQMSGEGKAGPPG 178 Score = 38.2 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 3/79 (3%) Query: 221 LYVKNINSETTDEQFQELFAKFG--PIVSASLEKDA-DGKLKGFGFVNYEKHEDAVKAVE 277 LY+ N+ TTDE E G I+ ++ +G+ KGF V + K ++ Sbjct: 71 LYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMD 130 Query: 278 ALNDSELNGEKLYVGRAQK 296 L EL+G+ V K Sbjct: 131 LLPKRELHGQNPVVTPVNK 149 >2MQN-A nrPDB Length = 216 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 69/192 (35%), Gaps = 39/192 (20%) Query: 128 IFIKNLHP-DIDNKALYDTFSVFGDILSSKIATDENGKSK-GFGFVHFEEEGAAKEAIDA 185 + + L ++ +++ F ++G++ K KSK G V + A AI Sbjct: 11 LMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFM-----KSKPGAAMVEMADGYAVDRAITH 65 Query: 186 LNGMLLNGQEIYV---APHLSRKERDSQLEETKAHYTN---------------------- 220 LN + GQ++ V + LE+ Y + Sbjct: 66 LNNNFMFGQKMNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQH 125 Query: 221 ----LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLK--GFGFVNYEKHEDAVK 274 L+ N E T+E F E+ + G + + K GK + G + ++ DA++ Sbjct: 126 PSNVLHFFNAPLEVTEENFFEICDELG-VKRPTSVKVFSGKSERSSSGLLEWDSKSDALE 184 Query: 275 AVEALNDSELNG 286 + LN ++ Sbjct: 185 TLGFLNHYQMKN 196 Score = 45.1 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 61/192 (31%), Gaps = 27/192 (14%) Query: 221 LYVKNINSE-TTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEAL 279 L V ++ ++ +F +G + K G V +A+ L Sbjct: 11 LMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGA----AMVEMADGYAVDRAITHL 66 Query: 280 NDSELNGEKLYVGRAQ---------KKNERMHVLKKQYEAYRLEKMAKYQGVN------- 323 N++ + G+K+ V ++ E K + R + + + Sbjct: 67 NNNFMFGQKMNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHP 126 Query: 324 ---LFVKNLDDSVDDEKLEEEFAPYG--TITSAKVMRTENGKSKGFGFVCFSTPEEATKA 378 L N V +E E G TS KV ++ +S G + + + +A + Sbjct: 127 SNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSS-GLLEWDSKSDALET 185 Query: 379 ITEKNQQIVAGK 390 + N + Sbjct: 186 LGFLNHYQMKNP 197 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 37/84 (44%), Gaps = 5/84 (5%) Query: 324 LFVKNLDD-SVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEK 382 L V LD ++ +++ F YG + K M+++ G V + +AIT Sbjct: 11 LMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGA----AMVEMADGYAVDRAITHL 66 Query: 383 NQQIVAGKPLYVAIAQRKDVRRSQ 406 N + G+ + V ++++ + Q Sbjct: 67 NNNFMFGQKMNVCVSKQPAIMPGQ 90 >5K1H-B nrPDB Length = 576 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 49/137 (35%), Gaps = 10/137 (7%) Query: 115 QRDPSLRKKGSGNIFIKNLHP------DIDNKALYDTFSVFGDILSSKIATDENGKSKGF 168 + P I + N+ + ++ FS FG I + +E+GK+KG+ Sbjct: 5 KDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN-DFYPEEDGKTKGY 63 Query: 169 GFVHFEEEGAAKEAIDALNGMLL-NGQEIYVAPHLSRKERDSQLEETKAHYTNLY--VKN 225 F+ + A +A+ +G L V + + +E + + N Sbjct: 64 IFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGN 123 Query: 226 INSETTDEQFQELFAKF 242 + + + ++ ++ Sbjct: 124 LRYWLEEAECRDQYSVI 140 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 18/147 (12%), Positives = 44/147 (29%), Gaps = 25/147 (17%) Query: 16 NIQDDQKQAATGSESQSVENSSASLYVGDLEP------SVSEAHLYDIFSPIGSVSSIRV 69 ++ D+ Q A G +S + V ++ + ++ IFS G +++ Sbjct: 2 DVLKDRPQEADGIDSV--------IVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFY 53 Query: 70 CRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKG-RLCRIMWSQRDPSLRKKGSGNI 128 + GY ++ + A++ + + R+ Sbjct: 54 P--EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWD 111 Query: 129 F--------IKNLHPDIDNKALYDTFS 147 + NL ++ D +S Sbjct: 112 IPEKQPFKDLGNLRYWLEEAECRDQYS 138 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 59/139 (42%), Gaps = 16/139 (11%) Query: 212 EETKAHYTNLYVKNINS------ETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVN 265 +E + + V N+ E ++F+KFG I + + DGK KG+ F+ Sbjct: 9 QEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYP-EEDGKTKGYIFLE 67 Query: 266 YEKHEDAVKAVEALNDSELNGE-KLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNL 324 Y AV AV+ + +L+ + V ++ M + + + + + ++ Sbjct: 68 YASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTI----SDEWDIPEKQPFKD--- 120 Query: 325 FVKNLDDSVDDEKLEEEFA 343 + NL +++ + ++++ Sbjct: 121 -LGNLRYWLEEAECRDQYS 138 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 336 EKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGK-PLYV 394 + + F+ +G IT+ E+GK+KG+ F+ +++P A A+ + + + V Sbjct: 36 NVIHKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRV 94 Query: 395 AI 396 + Sbjct: 95 NL 96 >5O20-A nrPDB Length = 180 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 27/82 (32%), Gaps = 6/82 (7%) Query: 107 RLCRIMWSQRDPSL-RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKS 165 R + + P K S +FI + ++ L + F ++ S + S Sbjct: 31 RPKPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVIL-----NNS 85 Query: 166 KGFGFVHFEEEGAAKEAIDALN 187 + FV A+ + N Sbjct: 86 RKHAFVKVYSRHEAENVLQNFN 107 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 44/132 (33%), Gaps = 13/132 (9%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 K LF+ + ++ + L P+ + S ++ S+ FV + EA Sbjct: 47 KVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSV-IL----NNSRKHAFVKVYSRHEAEN 101 Query: 378 AITEKNQQIVAGKPLYVAIAQ---RKDVRRSQLAQQIQARNQMRYQQATAAAAAAAAGMP 434 + N PL +D Q I +++ + +A G Sbjct: 102 VLQNFN--KDGALPLRTRWGVGFGPRDCCDYQHGYSIIPMHRLTDADKKWSVSAQWGGTS 159 Query: 435 GQFMPPMFYGVM 446 GQ P+ G++ Sbjct: 160 GQ---PLVTGIV 168 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 26/64 (40%), Gaps = 6/64 (9%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 S +L++G + ++ E L ++ P V S+ + S +A+V + Sbjct: 50 SRTLFIGGVPLNMKEWDLANVLKPFAEVQSVIL------NNSRKHAFVKVYSRHEAENVL 103 Query: 97 EQLN 100 + N Sbjct: 104 QNFN 107 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 31/100 (31%), Gaps = 11/100 (11%) Query: 187 NGMLLNGQEIYVAPHLSRKERDSQLEET------KAHYTNLYVKNINSETTDEQFQELFA 240 N L E+ V+ + + + + T K + L++ + + + Sbjct: 13 NNHHLYPDELNVSNNPHYRPKPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLK 72 Query: 241 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 F + S L + FV +A ++ N Sbjct: 73 PFAEVQSVIL-----NNSRKHAFVKVYSRHEAENVLQNFN 107 >5O1W-A nrPDB Length = 191 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 27/82 (32%), Gaps = 6/82 (7%) Query: 107 RLCRIMWSQRDPSL-RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKS 165 R + + P K S +FI + ++ L + F ++ S + S Sbjct: 21 RPKPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSVIL-----NNS 75 Query: 166 KGFGFVHFEEEGAAKEAIDALN 187 + FV A+ + N Sbjct: 76 RKHAFVKVYSRHEAENVLQNFN 97 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 44/132 (33%), Gaps = 13/132 (9%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 K LF+ + ++ + L P+ + S ++ S+ FV + EA Sbjct: 37 KVYSRTLFIGGVPLNMKEWDLANVLKPFAEVQSV-IL----NNSRKHAFVKVYSRHEAEN 91 Query: 378 AITEKNQQIVAGKPLYVAIAQ---RKDVRRSQLAQQIQARNQMRYQQATAAAAAAAAGMP 434 + N PL +D Q I +++ + +A G Sbjct: 92 VLQNFN--KDGALPLRTRWGVGFGPRDCCDYQHGYSIIPMHRLTDADKKWSVSAQWGGTS 149 Query: 435 GQFMPPMFYGVM 446 GQ P+ G++ Sbjct: 150 GQ---PLVTGIV 158 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 26/64 (40%), Gaps = 6/64 (9%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 S +L++G + ++ E L ++ P V S+ + S +A+V + Sbjct: 40 SRTLFIGGVPLNMKEWDLANVLKPFAEVQSVIL------NNSRKHAFVKVYSRHEAENVL 93 Query: 97 EQLN 100 + N Sbjct: 94 QNFN 97 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 31/100 (31%), Gaps = 11/100 (11%) Query: 187 NGMLLNGQEIYVAPHLSRKERDSQLEET------KAHYTNLYVKNINSETTDEQFQELFA 240 N L E+ V+ + + + + T K + L++ + + + Sbjct: 3 NNHHLYPDELNVSNNPHYRPKPVSYDSTLPPDHIKVYSRTLFIGGVPLNMKEWDLANVLK 62 Query: 241 KFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 F + S L + FV +A ++ N Sbjct: 63 PFAEVQSVIL-----NNSRKHAFVKVYSRHEAENVLQNFN 97 >6FEC-u nrPDB Length = 636 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 37 SASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAIT-KTSLGYAYVNFNDHEAGRKA 95 + ++G+L V+E + + F + +S++R+ R+ + G+ Y F D ++ A Sbjct: 120 PYTAFLGNLPYDVTEESIKEFFRGLN-ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSA 178 Query: 96 IEQLNYTPIKGRLCRIMWS-QRDPSLRKKGS 125 + N + R R+ + Q R S Sbjct: 179 LSL-NEESLGNRRIRVDVADQAQDKDRDDRS 208 Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 46/102 (45%), Gaps = 7/102 (6%) Query: 198 VAPHLSRKERDSQLEET---KAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA 254 + P R R+ ++ + K+ ++ N+ + T+E +E F I + L ++ Sbjct: 97 ILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGL-NISAVRLPREP 155 Query: 255 DG--KLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRA 294 +LKGFG+ +E + + A+ N+ L ++ V A Sbjct: 156 SNPERLKGFGYAEFEDLDSLLSALSL-NEESLGNRRIRVDVA 196 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 44/115 (38%), Gaps = 10/115 (8%) Query: 102 TPIKGRLCRIMWSQRDPSLRKKGS------GNIFIKNLHPDIDNKALYDTFSVFGDILSS 155 PI + + F+ NL D+ +++ + F +I + Sbjct: 91 PPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGL-NISAV 149 Query: 156 KIATDENG--KSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERD 208 ++ + + + KGFG+ FE+ + A +LN L + I V +++D Sbjct: 150 RLPREPSNPERLKGFGYAEFEDLDSLLSA-LSLNEESLGNRRIRVDVADQAQDKD 203 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 39/89 (43%), Gaps = 4/89 (4%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENG--KSKGFGFVCFSTPEEA 375 K F+ NL V +E ++E F I++ ++ R + + KGFG+ F + Sbjct: 117 KSPPYTAFLGNLPYDVTEESIKEFFRGL-NISAVRLPREPSNPERLKGFGYAEFEDLDSL 175 Query: 376 TKAITEKNQQIVAGKPLYVAIAQRKDVRR 404 A N++ + + + V +A + + Sbjct: 176 LSA-LSLNEESLGNRRIRVDVADQAQDKD 203 >3U1M-A nrPDB Length = 240 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 14/78 (17%) Query: 123 KGSGNIFIKNLHPDIDNKALYD---------TFSVFGDILSSKIATDENGKSKGFGFVHF 173 K + +++ + +++K L FS GDI + +SK GFV F Sbjct: 132 KKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV-----ESKNCGFVKF 186 Query: 174 EEEGAAKEAIDALNGMLL 191 + + A+ A +A++ L Sbjct: 187 KYQANAEFAKEAMSNQTL 204 Score = 45.5 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 37/118 (31%), Gaps = 26/118 (22%) Query: 32 SVENSSASLYVGDLE---------PSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 S + +LYVG ++ P+ E+ + +FS +G + IR S Sbjct: 129 SFRKKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV------ESKNCG 182 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNK 140 +V F A E ++ + PS ++ L + Sbjct: 183 FVKFKYQANAEFAKEAMSNQTL-----------LLPSDKEWDDRREGTGLLVKWANED 229 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 14/79 (17%) Query: 215 KAHYTNLYVKNINSETT---------DEQFQELFAKFGPIVSASLEKDADGKLKGFGFVN 265 + LYV I+ + + + +F++ G I + K GFV Sbjct: 131 RKKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV-----ESKNCGFVK 185 Query: 266 YEKHEDAVKAVEALNDSEL 284 ++ +A A EA+++ L Sbjct: 186 FKYQANAEFAKEAMSNQTL 204 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 29/77 (37%), Gaps = 14/77 (18%) Query: 320 QGVNLFVKNLDDSVDDEKLEEE---------FAPYGTITSAKVMRTENGKSKGFGFVCFS 370 + L+V +D +++ + L+ F+ G I + + SK GFV F Sbjct: 133 KNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVE-----SKNCGFVKFK 187 Query: 371 TPEEATKAITEKNQQIV 387 A A + Q + Sbjct: 188 YQANAEFAKEAMSNQTL 204 >5LJ5-M nrPDB Length = 339 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 50/133 (37%), Gaps = 29/133 (21%) Query: 123 KGSGNIFIKNLHPDIDNKALYD---------TFSVFGDILSSKIATDENGKSKGFGFVHF 173 K + +++ + +++K L FS GDI + +SK GFV F Sbjct: 132 KKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV-----ESKNCGFVKF 186 Query: 174 EEEGAAKEAIDALNGMLL------------NGQEIYVAPHLSRKERDSQL---EETKAHY 218 + + A+ A +A++ L G + V + +Q EE K Sbjct: 187 KYQANAEFAKEAMSNQTLLLPSDKEWDDRREGTGLLVKWANEDPDPAAQKRLQEELKLES 246 Query: 219 TNLYVKNINSETT 231 N+ V IN+ T Sbjct: 247 LNMMVHLINNNTN 259 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 37/118 (31%), Gaps = 26/118 (22%) Query: 32 SVENSSASLYVGDLE---------PSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYA 82 S + +LYVG ++ P+ E+ + +FS +G + IR S Sbjct: 129 SFRKKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV------ESKNCG 182 Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNK 140 +V F A E ++ + PS ++ L + Sbjct: 183 FVKFKYQANAEFAKEAMSNQTL-----------LLPSDKEWDDRREGTGLLVKWANED 229 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 14/79 (17%) Query: 215 KAHYTNLYVKNINSETT---------DEQFQELFAKFGPIVSASLEKDADGKLKGFGFVN 265 + LYV I+ + + + +F++ G I + K GFV Sbjct: 131 RKKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYV-----ESKNCGFVK 185 Query: 266 YEKHEDAVKAVEALNDSEL 284 ++ +A A EA+++ L Sbjct: 186 FKYQANAEFAKEAMSNQTL 204 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 29/77 (37%), Gaps = 14/77 (18%) Query: 320 QGVNLFVKNLDDSVDDEKLEEE---------FAPYGTITSAKVMRTENGKSKGFGFVCFS 370 + L+V +D +++ + L+ F+ G I + + SK GFV F Sbjct: 133 KNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVE-----SKNCGFVKFK 187 Query: 371 TPEEATKAITEKNQQIV 387 A A + Q + Sbjct: 188 YQANAEFAKEAMSNQTL 204 >2E5G-A nrPDB Length = 94 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 7/76 (9%) Query: 126 GNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKG-FGFVHFEEEGAAKEAID 184 ++F+ +D+ L + F FG + + + D++ KG F V + G A+EA+ Sbjct: 9 RSVFVSGFPRGVDSAQLSEYFLAFGPV--ASVVMDKD---KGVFAIVEMGDVG-AREAVL 62 Query: 185 ALNGMLLNGQEIYVAP 200 + + L G + V P Sbjct: 63 SQSQHSLGGHRLRVRP 78 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 32/81 (39%), Gaps = 6/81 (7%) Query: 38 ASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIE 97 S++V V A L + F G V+S+ + +D +A V D R+A+ Sbjct: 9 RSVFVSGFPRGVDSAQLSEYFLAFGPVASVVMDKDKGV-----FAIVEMGDVG-AREAVL 62 Query: 98 QLNYTPIKGRLCRIMWSQRDP 118 + + G R+ ++ Sbjct: 63 SQSQHSLGGHRLRVRPREQKE 83 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 5/82 (6%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITE 381 ++FV VD +L E F +G + S VM + G F V A +A+ Sbjct: 9 RSVFVSGFPRGVDSAQLSEYFLAFGPVASV-VMDKDKGV---FAIVEMGD-VGAREAVLS 63 Query: 382 KNQQIVAGKPLYVAIAQRKDVR 403 ++Q + G L V ++K+ + Sbjct: 64 QSQHSLGGHRLRVRPREQKEFQ 85 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 7/81 (8%) Query: 219 TNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKG-FGFVNYEKHEDAVKAVE 277 +++V Q E F FGP+ S ++KD KG F V A +AV Sbjct: 9 RSVFVSGFPRGVDSAQLSEYFLAFGPVASVVMDKD-----KGVFAIVEMGDVG-AREAVL 62 Query: 278 ALNDSELNGEKLYVGRAQKKN 298 + + L G +L V ++K Sbjct: 63 SQSQHSLGGHRLRVRPREQKE 83 >2NLW-A nrPDB Length = 105 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 36/87 (41%), Gaps = 7/87 (8%) Query: 115 QRDPSLRKKGSGNIFIKNLHP------DIDNKALYDTFSVFGDILSSKIATDENGKSKGF 168 + P I + N+ + ++ FS FG I + +E+GK+KG+ Sbjct: 5 KDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN-DFYPEEDGKTKGY 63 Query: 169 GFVHFEEEGAAKEAIDALNGMLLNGQE 195 F+ + A +A+ +G L+ Q Sbjct: 64 IFLEYASPAHAVDAVKNADGYKLDKQH 90 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 7/80 (8%) Query: 212 EETKAHYTNLYVKNINS------ETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVN 265 +E + + V N+ E ++F+KFG I + + DGK KG+ F+ Sbjct: 9 QEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYP-EEDGKTKGYIFLE 67 Query: 266 YEKHEDAVKAVEALNDSELN 285 Y AV AV+ + +L+ Sbjct: 68 YASPAHAVDAVKNADGYKLD 87 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 14/111 (12%), Positives = 36/111 (32%), Gaps = 17/111 (15%) Query: 16 NIQDDQKQAATGSESQSVENSSASLYVGDLEP------SVSEAHLYDIFSPIGSVSSIRV 69 ++ D+ Q A G +S + V ++ + ++ IFS G +++ Sbjct: 2 DVLKDRPQEADGIDSV--------IVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFY 53 Query: 70 CRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKG-RLCRIMWSQRDPS 119 + GY ++ + A++ + + R+ Sbjct: 54 P--EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDK 102 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 336 EKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGK-PLYV 394 + + F+ +G IT+ E+GK+KG+ F+ +++P A A+ + + + V Sbjct: 36 NVIHKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRV 94 Query: 395 AI 396 + Sbjct: 95 NL 96 >2KRB-A nrPDB Length = 81 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 235 FQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELN 285 ++F+KFG I + + DGK KG+ F+ Y AV AV+ + +L+ Sbjct: 24 IHKIFSKFGKITNDFYP-EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLD 73 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Query: 125 SGNIFIKNLHP------DIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGA 178 I + N+ + ++ FS FG I + +E+GK+KG+ F+ + Sbjct: 1 DSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAH 59 Query: 179 AKEAIDALNGMLLNGQE 195 A +A+ +G L+ Q Sbjct: 60 AVDAVKNADGYKLDKQH 76 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 7/58 (12%), Positives = 22/58 (37%), Gaps = 2/58 (3%) Query: 51 EAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRL 108 + ++ IFS G +++ + GY ++ + A++ + + + Sbjct: 21 KNVIHKIFSKFGKITNDFYP--EEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQH 76 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 336 EKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGK 390 + + F+ +G IT+ E+GK+KG+ F+ +++P A A+ + + + Sbjct: 22 NVIHKIFSKFGKITN-DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQ 75 >4YH8-A nrPDB Length = 216 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 46/132 (34%), Gaps = 6/132 (4%) Query: 281 DSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDD--EKL 338 + +GE+ + + + Y+ E K L + D E + Sbjct: 25 GACRHGERCSRKHVKPNFSQTILCPNMYKNPIHEPNGKKFTQR----ELAEQFDAFYEDM 80 Query: 339 EEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQ 398 EF+ YG + V G +V F E A AI + N + + +P+Y ++ Sbjct: 81 FCEFSKYGEVEQLVVCDNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPVYAELSP 140 Query: 399 RKDVRRSQLAQQ 410 D R + Q Sbjct: 141 VTDFREACCRQH 152 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 32/70 (45%) Query: 140 KALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA 199 + ++ FS +G++ + + G +V F+ E +A+ AID LN + + +Y Sbjct: 78 EDMFCEFSKYGEVEQLVVCDNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPVYAE 137 Query: 200 PHLSRKERDS 209 R++ Sbjct: 138 LSPVTDFREA 147 Score = 35.9 bits (81), Expect = 0.054, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 25/58 (43%) Query: 233 EQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLY 290 E F+K+G + + + L G +V ++ E A A++ LN + +Y Sbjct: 78 EDMFCEFSKYGEVEQLVVCDNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPVY 135 Score = 35.5 bits (80), Expect = 0.068, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 58 FSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLC 109 FS G V + VC D + +G YV F E+ + AI+ LN R Sbjct: 84 FSKYGEVEQLVVC-DNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPV 134 >3S8S-A nrPDB Length = 110 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 28/66 (42%) Query: 45 LEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPI 104 L +V E L D+ G V + + T+ LG A V F ++ ++ L+ T + Sbjct: 14 LNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSV 73 Query: 105 KGRLCR 110 G + Sbjct: 74 MGNIIH 79 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 1/76 (1%) Query: 133 LHPDIDNKALYDTFSVFGDILSSKI-ATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLL 191 L+ ++ L D +G++ +I K G V F AKE + L+ + Sbjct: 14 LNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSV 73 Query: 192 NGQEIYVAPHLSRKER 207 G I+ + ++R Sbjct: 74 MGNIIHAQLDIKGQQR 89 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 329 LDDSVDDEKLEEEFAPYGTITSAKV-MRTENGKSKGFGFVCFSTPEEATKAITEKNQQIV 387 L+D+V + L++ YG + ++ + K G V F++ A + + + V Sbjct: 14 LNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSV 73 Query: 388 AGKPLYVAIAQRKDVR 403 G ++ + + R Sbjct: 74 MGNIIHAQLDIKGQQR 89 >1JMT-A nrPDB Length = 104 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 28/67 (41%) Query: 331 DSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGK 390 D +E E YG + V G +V F E+A KA+ + N + G+ Sbjct: 37 DEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQ 96 Query: 391 PLYVAIA 397 P++ ++ Sbjct: 97 PIHAELS 103 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 25/64 (39%) Query: 139 NKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYV 198 + + +G++ + + G +V F E A++A+ LN NGQ I+ Sbjct: 41 EEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHA 100 Query: 199 APHL 202 Sbjct: 101 ELSP 104 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 33/62 (53%) Query: 229 ETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEK 288 E +E F E+ K+G + ++ + L G +V + + EDA KAV LN+ NG+ Sbjct: 38 EFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQP 97 Query: 289 LY 290 ++ Sbjct: 98 IH 99 Score = 37.4 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 51 EAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCR 110 E ++ G V + VC D + +G YV F E KA+ LN G+ Sbjct: 41 EEVFTEMEEKYGEVEEMNVC-DNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIH 99 Query: 111 IMWS 114 S Sbjct: 100 AELS 103 >4QU7-A nrPDB Length = 81 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAV 276 ++++ + + + FA P+ ++E + GK G V++E HEDAV A+ Sbjct: 4 VHMRGLPFQANAQDIINFFAPLKPV-RITMEYSSSGKATGEADVHFETHEDAVAAM 58 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 26/56 (46%), Gaps = 1/56 (1%) Query: 324 LFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAI 379 + ++ L + + + FAP + + + +GK+ G V F T E+A A+ Sbjct: 4 VHMRGLPFQANAQDIINFFAPLKPV-RITMEYSSSGKATGEADVHFETHEDAVAAM 58 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAI 183 + ++ L + + + + F+ + + +GK+ G VHFE A A+ Sbjct: 4 VHMRGLPFQANAQDIINFFAPL-KPVRITMEYSSSGKATGEADVHFETHEDAVAAM 58 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 24/57 (42%), Gaps = 2/57 (3%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAI 96 +++ L + + + F+P+ V + + + G A V+F HE A+ Sbjct: 4 VHMRGLPFQANAQDIINFFAPLKPVR--ITMEYSSSGKATGEADVHFETHEDAVAAM 58 >4NOX-A nrPDB Length = 746 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 76 KTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRL-CRIMWSQRDPS-LRKKGSGNIFI 130 SL +A+V ++ A+ QL+Y P+ + R+ R+ F+ Sbjct: 87 GMSLRFAFVEYSSPAEASAAVRQLDYVPLDKKHTLRVNKLTDIDRYGREGRISEEFV 143 Score = 36.6 bits (83), Expect = 0.034, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 27/76 (35%), Gaps = 8/76 (10%) Query: 248 ASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGE-KLYVG-------RAQKKNE 299 + DG F FV Y +A AV L+ L+ + L V ++ Sbjct: 79 IYMPMGDDGMSLRFAFVEYSSPAEASAAVRQLDYVPLDKKHTLRVNKLTDIDRYGREGRI 138 Query: 300 RMHVLKKQYEAYRLEK 315 + + E ++ ++ Sbjct: 139 SEEFVPPKIEPFQEKE 154 Score = 32.8 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%) Query: 162 NGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQE 195 +G S F FV + A A+ L+ + L+ + Sbjct: 86 DGMSLRFAFVEYSSPAEASAAVRQLDYVPLDKKH 119 >5Z9X-A nrPDB Length = 409 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/118 (11%), Positives = 40/118 (33%), Gaps = 14/118 (11%) Query: 117 DPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEE 176 + + +F+ + ++ ++ L S G + + + F F Sbjct: 306 SKEMLEVEKAKLFLHKIPNNVPSEELEQVLS--GKF-TLDVKQAKTQGRYYCAFALFHSS 362 Query: 177 GAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQ 234 A +A + ++G I + L ++ ++ + ++YV + ++ Sbjct: 363 EDADQAFEHIDG-------IEMTDSLGLPQKVVIIKLSSGSRASIYV----RKMVQDE 409 Score = 38.2 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 20/136 (14%), Positives = 45/136 (33%), Gaps = 11/136 (8%) Query: 4 ITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGS 63 + D +A L + + + + +E A L++ + +V L Sbjct: 281 VHDASAAMKLALAVVEKRVDTTIKPSKEMLEVEKAKLFLHKIPNNVPSEELEQ------- 333 Query: 64 VSSIRVCRDAITKTSLG---YAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSL 120 V S + D + G A+ F+ E +A E ++ + + L Sbjct: 334 VLSGKFTLDVKQAKTQGRYYCAFALFHSSEDADQAFEHIDGIEMTD-SLGLPQKVVIIKL 392 Query: 121 RKKGSGNIFIKNLHPD 136 +I+++ + D Sbjct: 393 SSGSRASIYVRKMVQD 408 Score = 36.2 bits (82), Expect = 0.039, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 9/79 (11%) Query: 315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKG---FGFVCFST 371 +M + + LF+ + ++V E+LE+ + G T + + K++G F F + Sbjct: 308 EMLEVEKAKLFLHKIPNNVPSEELEQVLS--GKFT----LDVKQAKTQGRYYCAFALFHS 361 Query: 372 PEEATKAITEKNQQIVAGK 390 E+A +A + + Sbjct: 362 SEDADQAFEHIDGIEMTDS 380 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 30/82 (36%), Gaps = 11/82 (13%) Query: 209 SQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKD-ADGKLKG---FGFV 264 E + L++ I + E+ ++ ++S D K +G F Sbjct: 305 PSKEMLEVEKAKLFLHKIPNNVPSEELEQ-------VLSGKFTLDVKQAKTQGRYYCAFA 357 Query: 265 NYEKHEDAVKAVEALNDSELNG 286 + EDA +A E ++ E+ Sbjct: 358 LFHSSEDADQAFEHIDGIEMTD 379 >3DXB-A nrPDB Length = 222 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 61/169 (36%), Gaps = 20/169 (11%) Query: 134 HPDIDNKALYDTFSVF-GDILSSKIATDEN-GKSKGFG------FVHFEEEGAAKEAIDA 185 + L + + G + +K+ D+N G + +G + F+ A + A Sbjct: 44 PCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGA 103 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPI 245 L+ L + + S E + +I+ + + + E KFG + Sbjct: 104 LSKGQLK-EFLDANLAGSAMESTVMVLRNMVDPK-----DIDDDL-EGEVTEECGKFGAV 156 Query: 246 VSASLEKDADGKLKGFG-----FVNYEKHEDAVKAVEALNDSELNGEKL 289 + ++ G+ + FV + + KA++ALN G K+ Sbjct: 157 NRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKV 205 Score = 37.8 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 330 DDSVDDE---KLEEEFAPYGTITSAKVMRTENGKSKGFG-----FVCFSTPEEATKAITE 381 +DD+ ++ EE +G + + + + G+ + FV FS E KAI Sbjct: 135 PKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQA 194 Query: 382 KNQQIVAGKPLYVAIAQRKDVRRSQLA 408 N + AG+ + + ++ S L+ Sbjct: 195 LNGRWFAGRKVVAEVYDQERFDNSDLS 221 Score = 36.2 bits (82), Expect = 0.039, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 34/87 (39%), Gaps = 8/87 (9%) Query: 134 HPDIDNK---ALYDTFSVFGDILSSKIATDENGKSKGFG-----FVHFEEEGAAKEAIDA 185 DID+ + + FG + I ++ G+ + FV F +AI A Sbjct: 135 PKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQA 194 Query: 186 LNGMLLNGQEIYVAPHLSRKERDSQLE 212 LNG G+++ + + +S L Sbjct: 195 LNGRWFAGRKVVAEVYDQERFDNSDLS 221 Score = 31.6 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 25/71 (35%), Gaps = 7/71 (9%) Query: 46 EPSVSEA---HLYDIFSPIGSVSSIRVCRDAITKTSLG----YAYVNFNDHEAGRKAIEQ 98 + + + + G+V+ + + ++ + +V F+ KAI+ Sbjct: 135 PKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQA 194 Query: 99 LNYTPIKGRLC 109 LN GR Sbjct: 195 LNGRWFAGRKV 205 >2VOD-A nrPDB Length = 193 Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 36/103 (34%) Query: 84 VNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALY 143 V + T I+ + + D + +++IK D + Sbjct: 68 VEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIK 127 Query: 144 DTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDAL 186 + G +L+ ++ + KG FV F+ +AK+ ++ Sbjct: 128 EWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETP 170 Score = 37.8 bits (86), Expect = 0.015, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 31/73 (42%) Query: 314 EKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPE 373 E + ++++K + ++E G + + ++ RT + KG FV F + E Sbjct: 102 EYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIE 161 Query: 374 EATKAITEKNQQI 386 A K + Q+ Sbjct: 162 SAKKFVETPGQKY 174 >5ZWN-S nrPDB Length = 298 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 36/231 (15%), Positives = 80/231 (34%), Gaps = 26/231 (11%) Query: 82 AYVNFNDHEAGRKAIEQLNYT--PIKGRLCRIMWSQ-------RDPSLRKKGSGNIFIKN 132 A++ F E + +E+ T ++GR R+ ++ +KKG+ + + Sbjct: 77 AFLTFVTQEEADRFLEKYTTTALKVQGRKVRMGKARTNSLLGLSIEMQKKKGNDETYNLD 136 Query: 133 LHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK--EAIDALNGML 190 + + + L D + +K + + + + A+ + Sbjct: 137 IKKVLKARKLKRKLRS--DDICAKKFRLKRQIRRLKHKLRSRKVEEAEIDRIVKEFETRR 194 Query: 191 LNGQ-----EIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPI 245 L + + ++ + S E L ++N+ S TT++ ++ + Sbjct: 195 LENMKSQQENLKQSQKPLKRAKVSNTMENPP-NKVLLIQNLPSGTTEQLLSQILGNE-AL 252 Query: 246 VSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDS-ELNGEKLYVGRAQ 295 V L + FV YE DA K L + +L + +G A+ Sbjct: 253 VEIRLVSVRN-----LAFVEYETVADATKIKNQLGSTYKLQNNDVTIGFAK 298 Score = 31.6 bits (70), Expect = 0.96, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 13/99 (13%) Query: 10 EQLENL-----NIQDDQKQAATGSESQSVENSSAS-LYVGDLEPSVSEAHLYDIFSPIGS 63 +LEN+ N++ QK S ++EN L + +L +E L I + Sbjct: 193 RRLENMKSQQENLKQSQKPLKRAKVSNTMENPPNKVLLIQNLPSGTTEQLLSQILGNE-A 251 Query: 64 VSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYT 102 + IR+ A+V + K QL T Sbjct: 252 LVEIRLVSVRNL------AFVEYETVADATKIKNQLGST 284 >2WBR-A nrPDB Length = 89 Score = 38.2 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 30/86 (34%), Gaps = 5/86 (5%) Query: 123 KGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEA 182 GS + +KNL ID L G ++S ++ G + A +A Sbjct: 5 WGSSWLLLKNLTAQIDGPTLRTLCMQHGPLVSFHPYLNQ-----GIALCKYTTREEANKA 59 Query: 183 IDALNGMLLNGQEIYVAPHLSRKERD 208 ALN +L I+ + + Sbjct: 60 QMALNNCVLANTTIFAESPSENEVQS 85 Score = 37.8 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 L +KN+ ++ + L + GP+VS + +G Y E+A KA ALN Sbjct: 10 LLLKNLTAQIDGPTLRTLCMQHGPLVSFHPYLN-----QGIALCKYTTREEANKAQMALN 64 Query: 281 DSELNGEKL 289 + L + Sbjct: 65 NCVLANTTI 73 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 20/70 (28%), Gaps = 6/70 (8%) Query: 40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQL 99 L + +L + L + G + S + G A + E KA L Sbjct: 10 LLLKNLTAQIDGPTLRTLCMQHGPLVSFHPYLN------QGIALCKYTTREEANKAQMAL 63 Query: 100 NYTPIKGRLC 109 N + Sbjct: 64 NNCVLANTTI 73 >2AD9-A nrPDB Length = 119 Score = 37.8 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 32/91 (35%), Gaps = 7/91 (7%) Query: 221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALN 280 ++++ + + T+ + L FG + + + K + F+ E A V Sbjct: 34 IHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKN-----QAFIEMNTEEAANTMVNYYT 88 Query: 281 DSE--LNGEKLYVGRAQKKNERMHVLKKQYE 309 L G+ +Y+ + K + Q Sbjct: 89 SVTPVLRGQPIYIQFSNHKELKTDSSPNQAR 119 Score = 36.2 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 37/93 (39%), Gaps = 8/93 (8%) Query: 24 AATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAY 83 + +S+S S +++ L V+E + + P G V+++ + + A+ Sbjct: 18 GSHMGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQ------AF 71 Query: 84 VNFNDHEAGRKAIEQLNY--TPIKGRLCRIMWS 114 + N EA + ++G+ I +S Sbjct: 72 IEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFS 104 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Query: 128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALN 187 I I+ L D+ + FG + + + +N F+ E AA ++ Sbjct: 34 IHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQ-----AFIEMNTEEAANTMVNYYT 88 Query: 188 GML--LNGQEIYVA 199 + L GQ IY+ Sbjct: 89 SVTPVLRGQPIYIQ 102 >1S79-A nrPDB Length = 103 Score = 37.4 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 37/93 (39%), Gaps = 3/93 (3%) Query: 317 AKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEAT 376 + ++++K + ++E G + + ++ RT + KG FV F + E A Sbjct: 7 NDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAK 66 Query: 377 KAITEKNQQIVAGKPLYV---AIAQRKDVRRSQ 406 K + Q+ L + +K+ R Q Sbjct: 67 KFVETPGQKYKETDLLILFKDDYFAKKNEERKQ 99 Score = 37.4 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 28/65 (43%) Query: 122 KKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKE 181 + +++IK D + + G +L+ ++ + KG FV F+ +AK+ Sbjct: 8 DVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKK 67 Query: 182 AIDAL 186 ++ Sbjct: 68 FVETP 72 >2PEH-A nrPDB Length = 105 Score = 35.5 bits (80), Expect = 0.071, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 26/62 (41%), Gaps = 4/62 (6%) Query: 232 DEQFQELFAKFGPIVSASLEKDADGKLKGFG---FVNYEKHEDAVKAVEALNDSELNGEK 288 + + +E K+G + + + G F+ +E+ E A+KAV LN G Sbjct: 27 EVETKEECEKYGKVGKC-VIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRV 85 Query: 289 LY 290 + Sbjct: 86 VK 87 Score = 32.8 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 33/86 (38%), Gaps = 7/86 (8%) Query: 332 SVDDE---KLEEEFAPYGTITSAKVMRTENGKSKGFG---FVCFSTPEEATKAITEKNQQ 385 VD++ + +EE YG + + G F+ F E A KA+ + N + Sbjct: 21 EVDEDLEVETKEECEKYGKVGKCVIFEIP-GAPDDEAVRIFLEFERVESAIKAVVDLNGR 79 Query: 386 IVAGKPLYVAIAQRKDVRRSQLAQQI 411 G+ + R LA+Q+ Sbjct: 80 YFGGRVVKACFYNLDKFRVLDLAEQV 105 Score = 32.8 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 26/71 (36%), Gaps = 13/71 (18%) Query: 136 DIDNK---ALYDTFSVFGDILSSKIAT------DENGKSKGFGFVHFEEEGAAKEAIDAL 186 ++D + +G + I DE + F+ FE +A +A+ L Sbjct: 21 EVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRI----FLEFERVESAIKAVVDL 76 Query: 187 NGMLLNGQEIY 197 NG G+ + Sbjct: 77 NGRYFGGRVVK 87 Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 14/28 (50%) Query: 83 YVNFNDHEAGRKAIEQLNYTPIKGRLCR 110 ++ F E+ KA+ LN GR+ + Sbjct: 60 FLEFERVESAIKAVVDLNGRYFGGRVVK 87 >2DIU-A nrPDB Length = 96 Score = 35.5 bits (80), Expect = 0.073, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 33/93 (35%), Gaps = 14/93 (15%) Query: 119 SLRKKGSGNIFIKNLHPDIDNKALYDTFSVF-----GDILSSKIATDENGKSKGFGFVHF 173 S +++ NL + D K++ + G +LS G S + F Sbjct: 3 SGSSGCHTLLYVYNLPANKDGKSVSNRLRRLSDNCGGKVLSI------TGCS---AILRF 53 Query: 174 EEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKE 206 + +A+ A + + G I V+ +E Sbjct: 54 INQDSAERAQKRMENEDVFGNRIIVSFTPKNRE 86 Score = 32.4 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 27/80 (33%), Gaps = 4/80 (5%) Query: 322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITE 381 L+V NL + D + + KV+ G S + F + A +A Sbjct: 10 TLLYVYNLPANKDGKSVSNRLRRLSDNCGGKVLSI-TGCS---AILRFINQDSAERAQKR 65 Query: 382 KNQQIVAGKPLYVAIAQRKD 401 + V G + V+ + Sbjct: 66 MENEDVFGNRIIVSFTPKNR 85 >3ES8-A nrPDB Length = 391 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 46/135 (34%), Gaps = 26/135 (19%) Query: 210 QLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKH 269 Q E LYV N + +E + +FG V K + F + Sbjct: 152 QKLEQGFDVFRLYVGK-NLDADEEFLSRVKEEFGSRVRI----------KSYDFSHLLNW 200 Query: 270 EDAVKAVEALNDSELNGEKLY---------------VGRAQKKNERMHVLKKQYEAYRLE 314 +DA +A++ L +L E + + +E + K+Q E + + Sbjct: 201 KDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTDYPISEHVWSFKQQQEMIKKD 260 Query: 315 KMAKYQGVNLFVKNL 329 + + +F+ L Sbjct: 261 AIDIFNISPVFIGGL 275 >3D45-A nrPDB Length = 507 Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 24/180 (13%), Positives = 52/180 (28%), Gaps = 31/180 (17%) Query: 9 AEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIR 68 + ++ + + + S+ + + Y+ L +L + SP Sbjct: 347 ETPFDPPKVESAEGFPSYDTASEQLHEAGYDAYITGLCFISMANYLGSLLSP-------- 398 Query: 69 VCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNI 128 + ++ S IE R+ I + + + ++ Sbjct: 399 -PKMCVSARSK---------------LIEPFFNKLFLMRVMDIPYLNLEGPDLQPKRDHV 442 Query: 129 FIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNG 188 + LY FS FG+I S I D+ FV + + A++ Sbjct: 443 LHVTFPKEWKTSDLYQLFSAFGNIQISWI--DDTS-----AFVSLSQPEQVQIAVNTSKY 495 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 39/122 (31%), Gaps = 11/122 (9%) Query: 260 GFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKY 319 G F++ + ++ + + ++ + K M V+ Y + Sbjct: 382 GLCFISMANYLGSLLSPPKM---CVSARSKLIEPFFNKLFLMRVMDIPYLNLEGPDLQPK 438 Query: 320 QGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAI 379 + L V L + F+ +G I + + + FV S PE+ A+ Sbjct: 439 RDHVLHVT-FPKEWKTSDLYQLFSAFGNIQISWI--DDTS-----AFVSLSQPEQVQIAV 490 Query: 380 TE 381 Sbjct: 491 NT 492 >3JB9-a nrPDB Length = 354 Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 34/89 (38%), Gaps = 7/89 (7%) Query: 209 SQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEK 268 + +L++ + E D + ++ F ++GP+ S A FVN++ Sbjct: 202 NMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAK-----CAFVNFKT 256 Query: 269 HEDAVKAVEAL--NDSELNGEKLYVGRAQ 295 A A A + + G +L V + Sbjct: 257 RSSAEIAAAASPDGNVVIEGFRLKVQWGK 285 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 9/67 (13%), Positives = 24/67 (35%), Gaps = 5/67 (7%) Query: 110 RIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFG 169 + S + K ++F+ + ++ + + F +G + S + Sbjct: 196 NVSLSINMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAK-----CA 250 Query: 170 FVHFEEE 176 FV+F+ Sbjct: 251 FVNFKTR 257 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 33/90 (36%), Gaps = 7/90 (7%) Query: 311 YRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFS 370 +E + +LF+ ++D + D K+ + F YG + S V FV F Sbjct: 201 INMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSV-VCSHRAK----CAFVNFK 255 Query: 371 TPEEATKAITEK--NQQIVAGKPLYVAIAQ 398 T A A ++ G L V + Sbjct: 256 TRSSAEIAAAASPDGNVVIEGFRLKVQWGK 285 Score = 28.9 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 33/84 (39%), Gaps = 8/84 (9%) Query: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93 + ASL++ +E +++ + F G + S+ VC A+VNF + Sbjct: 208 DKKIASLFLIGVEDELADYKIRKHFEQYGPLKSV-VCSHRAK-----CAFVNFKTRSSAE 261 Query: 94 KAIEQL--NYTPIKGRLCRIMWSQ 115 A I+G ++ W + Sbjct: 262 IAAAASPDGNVVIEGFRLKVQWGK 285 >2WAF-A nrPDB Length = 682 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 15/113 (13%) Query: 220 NLYVKNINSETTDEQFQELFAKF--GPIVSASLEKDADGK-LKGFGFVNYEKHEDAV--- 273 N++V N E+ E+ + F ++ G L ++ G K + F NY + Sbjct: 463 NMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDN 522 Query: 274 ---------KAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMA 317 A A N + + + L +Q + + K+ Sbjct: 523 YTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVN 575 >2ROK-A nrPDB Length = 100 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 26/71 (36%), Gaps = 8/71 (11%) Query: 118 PSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEG 177 P L+ K + + + LY FS FG+I S I D+ FV + Sbjct: 9 PDLQPKRDHVLHVT-FPKEWKTSDLYQLFSAFGNIQISWI--DDTS-----AFVSLSQPE 60 Query: 178 AAKEAIDALNG 188 + A++ Sbjct: 61 QVQIAVNTSKY 71 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 21/64 (32%), Gaps = 8/64 (12%) Query: 318 KYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATK 377 + L V L + F+ +G I + + + FV S PE+ Sbjct: 13 PKRDHVLHVT-FPKEWKTSDLYQLFSAFGNIQISWI--DDTS-----AFVSLSQPEQVQI 64 Query: 378 AITE 381 A+ Sbjct: 65 AVNT 68 Score = 29.7 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 17/52 (32%), Gaps = 7/52 (13%) Query: 227 NSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEA 278 E +LF+ FG I S D FV+ + E AV Sbjct: 24 PKEWKTSDLYQLFSAFGNI-QISWIDDTS------AFVSLSQPEQVQIAVNT 68 >1OWX-A nrPDB Length = 121 Score = 32.8 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 37/101 (36%), Gaps = 4/101 (3%) Query: 222 YVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALND 281 + +++ +T E LF+ G I + G +G EK ++A+ + N+ Sbjct: 23 FSGDLDDQTCREDLHILFSNHGEIKWIDFVR---GAKEGIILFK-EKAKEALGKAKDANN 78 Query: 282 SELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGV 322 L V + E K+ + E + K++ Sbjct: 79 GNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSK 119 >6G90-A nrPDB Length = 298 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 175 EEGAAKEAIDALNGMLLNGQ-----EIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSE 229 EE + L + + ++ + S E L ++N+ S Sbjct: 179 EEAEIDRIVKEFETRRLENMKSQQENLKQSQKPLKRAKVSNTMENPP-NKVLLIQNLPSG 237 Query: 230 TTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDS-ELNGEK 288 TT++ ++ +V L + FV YE DA K L + +L Sbjct: 238 TTEQLLSQILGNE-ALVEIRLVSVRN-----LAFVEYETVADATKIKNQLGSTYKLQNND 291 Query: 289 LYVGRAQ 295 + +G A+ Sbjct: 292 VTIGFAK 298 Score = 31.6 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 13/99 (13%) Query: 10 EQLENL-----NIQDDQKQAATGSESQSVENSSAS-LYVGDLEPSVSEAHLYDIFSPIGS 63 +LEN+ N++ QK S ++EN L + +L +E L I + Sbjct: 193 RRLENMKSQQENLKQSQKPLKRAKVSNTMENPPNKVLLIQNLPSGTTEQLLSQILGNE-A 251 Query: 64 VSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYT 102 + IR+ A+V + K QL T Sbjct: 252 LVEIRLVSVRNL------AFVEYETVADATKIKNQLGST 284 >3CTR-A nrPDB Length = 101 Score = 32.4 bits (72), Expect = 0.62, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 26/87 (29%), Gaps = 7/87 (8%) Query: 134 HPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNG 193 + LY FS FG+I S I D+ FV + K A++ Sbjct: 14 PKEWKTSDLYQLFSAFGNIQISWI--DDTS-----AFVSLSQPEQVKIAVNTSKYAESYR 66 Query: 194 QEIYVAPHLSRKERDSQLEETKAHYTN 220 + Y ++E + Sbjct: 67 IQTYAEYMGRKQEEKQIKRKWTEDSWK 93 Score = 30.5 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 31/92 (33%), Gaps = 7/92 (7%) Query: 227 NSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNG 286 E +LF+ FG I S D FV+ + E AV +E Sbjct: 14 PKEWKTSDLYQLFSAFGNI-QISWIDDTS------AFVSLSQPEQVKIAVNTSKYAESYR 66 Query: 287 EKLYVGRAQKKNERMHVLKKQYEAYRLEKMAK 318 + Y +K E + +K E E +K Sbjct: 67 IQTYAEYMGRKQEEKQIKRKWTEDSWKEADSK 98 >2DNR-A nrPDB Length = 91 Score = 32.4 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 20/60 (33%), Gaps = 9/60 (15%) Query: 52 AHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRI 111 L F+ G V IR D + +V F + + + LN + R I Sbjct: 30 DELLQQFASFGEVILIRFVEDKM--------WVTFLEGSSALNVL-SLNGKELLNRTITI 80 Score = 32.0 bits (71), Expect = 0.75, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 26/64 (40%), Gaps = 8/64 (12%) Query: 336 EKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVA 395 ++L ++FA +G + + + + +V F A + N + + + + +A Sbjct: 30 DELLQQFASFGEVILIRFVEDKM-------WVTFLEGSSALNVL-SLNGKELLNRTITIA 81 Query: 396 IAQR 399 + Sbjct: 82 LKSP 85 >3COX-A nrPDB Length = 507 Score = 32.0 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 34/215 (15%), Positives = 67/215 (31%), Gaps = 44/215 (20%) Query: 213 ETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDA 272 +T ++ +N + D + F+ + ++ Sbjct: 47 DTPGSDGKIFCGMLNPDKRSMWLA----------------DKTDQPVS-NFMGFGINKSI 89 Query: 273 VKAVEALNDSELNGEKLYVGRAQ--------------KKNERMHVLKKQYEAYRLEKMAK 318 + V L+ +G K+Y GR K+N +L K Sbjct: 90 DRYVGVLDSERFSGIKVYQGRGVGGGSLVNGGMAVTPKRNYFEEILPSVDSNEMYNKYFP 149 Query: 319 YQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGF--GFV--CFSTPEE 374 L V N+D + + +FA G + + GF FV + Sbjct: 150 RANTGLGVNNIDQAWFESTEWYKFARTGR---------KTAQRSGFTTAFVPNVYDFEYM 200 Query: 375 ATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQ 409 +A + + + G+ +Y A +K + ++ LAQ Sbjct: 201 KKEAAGQVTKSGLGGEVIYGNNAGKKSLDKTYLAQ 235 >2JBS-A nrPDB Length = 422 Score = 32.0 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 63/178 (35%), Gaps = 11/178 (6%) Query: 239 FAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKN 298 F K + + G G + A A+ N + +G K+Y ++ Sbjct: 151 FGKVEEVEGGIILNGDYGWSSGC--------DHAEYAIVGFNRFDADGNKIYSFGVIPRS 202 Query: 299 ERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN 358 + V +A + + VN+F+ S + +E + A +G +K+ T Sbjct: 203 DYEIVDNWYAQAIKSSGSKMLKLVNVFIPEYRISKAKDMMEGKSAGFGLYPDSKIFYTPY 262 Query: 359 GK--SKGFGFVCFSTPEEATKAITEKNQQIVAGKP-LYVAIAQRKDVRRSQLAQQIQA 413 + GF V E +A EK + V V +A +R ++ Q+ A Sbjct: 263 RPYFASGFSAVSLGIAERMIEAFKEKQRNRVRAYTGANVGLATPALMRIAESTHQVAA 320 >5ZOK-B nrPDB Length = 132 Score = 31.6 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%), Gaps = 2/68 (2%) Query: 351 AKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQ 410 + +N + +G +V +PE A KA + GK + V R D + Q Sbjct: 63 VHIAVDKNSR-EGCVYVKCLSPEYAGKAFKALHGSWFDGKLVTVKY-LRLDRYHHRFPQA 120 Query: 411 IQARNQMR 418 + + ++ Sbjct: 121 LTSNTPLK 128 >3LJS-A nrPDB Length = 338 Score = 31.6 bits (70), Expect = 0.94, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 21/50 (42%), Gaps = 2/50 (4%) Query: 325 FVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEE 374 FV L + + L + FA G +T ++RT K+ FV E Sbjct: 55 FVGMLGSDMFGDFLFDSFAEAGVVTDG-IVRTSTAKT-ALAFVALDAHGE 102 >2O1T-A nrPDB Length = 450 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 26/194 (13%), Positives = 73/194 (37%), Gaps = 15/194 (7%) Query: 188 GMLLNGQEI-YVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIV 246 G++ G + + P R ++ + +E KA Y + + E+ D F G + Sbjct: 13 GLVPRGSHMNDIKPIWQRPSKEVEDDEYKAFYKS-----FSKESDDPMAYIHFTAEGEVT 67 Query: 247 SASLEKDADGKLKGFGFVNYEKHED------AVKAVEALNDSELNGEKLYVGRAQKKNER 300 S+ +G F Y + + + ++ + L + ++ Sbjct: 68 FKSILFVPTSAPRGL-FDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDD 126 Query: 301 M--HVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTEN 358 + +V ++ + ++L K+ + + V + + D++ + + +GT V+ + Sbjct: 127 LPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHS 186 Query: 359 GKSKGFGFVCFSTP 372 +++ + F + Sbjct: 187 NRTRLAKLLRFQSS 200 >3TQS-A nrPDB Length = 255 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 18/44 (40%) Query: 31 QSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAI 74 SV+ VG+L ++S L+ +FS I + + Sbjct: 90 SSVKTDKPLRVVGNLPYNISTPLLFHLFSQIHCIEDMHFMLQKE 133 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.130 0.325 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,955,799 Number of Sequences: 36641 Number of extensions: 806431 Number of successful extensions: 3570 Number of sequences better than 10.0: 169 Number of HSP's better than 10.0 without gapping: 228 Number of HSP's successfully gapped in prelim test: 81 Number of HSP's that attempted gapping in prelim test: 2003 Number of HSP's gapped (non-prelim): 976 length of query: 577 length of database: 10,336,785 effective HSP length: 102 effective length of query: 475 effective length of database: 6,599,403 effective search space: 3134716425 effective search space used: 3134716425 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 62 (28.5 bits)