BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P03952 (638 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6I44-A nrPDB 1281 0.0 2F83-A nrPDB 783 0.0 5TJX-A nrPDB 546 e-155 5GVT-A nrPDB 428 e-120 6AOD-C nrPDB 345 2e-95 3W94-A nrPDB 208 5e-54 3T2N-A nrPDB 200 1e-51 1P57-B nrPDB 196 3e-50 3DFJ-A nrPDB 196 3e-50 4DGJ-A nrPDB 196 4e-50 3E0N-B nrPDB 195 4e-50 1EKB-B nrPDB 194 8e-50 2F91-A nrPDB 191 6e-49 1FIW-A nrPDB 179 5e-45 1FIZ-A nrPDB 178 7e-45 1LTO-A nrPDB 174 1e-43 4Z6A-H nrPDB 172 3e-43 3P8G-A nrPDB 172 4e-43 3LC3-A nrPDB 172 4e-43 4MPW-A nrPDB 172 5e-43 1X7A-C nrPDB 171 8e-43 2CGA-A nrPDB 171 1e-42 5UGG-A nrPDB 164 9e-41 2OQ5-A nrPDB 164 9e-41 5FXL-A nrPDB 164 1e-40 4DUR-A nrPDB 163 2e-40 1F7Z-A nrPDB 162 3e-40 4AN7-A nrPDB 162 3e-40 1YC0-A nrPDB 160 1e-39 2R0L-A nrPDB 158 8e-39 1UTJ-A nrPDB 155 4e-38 1A0J-A nrPDB 154 8e-38 3F6U-H nrPDB 154 1e-37 1BRU-P nrPDB 152 4e-37 1MKW-K nrPDB 151 7e-37 2EEK-A nrPDB 151 1e-36 4WWY-A nrPDB 150 1e-36 5C67-A nrPDB 150 2e-36 4H4F-A nrPDB 150 2e-36 4NZQ-A nrPDB 148 6e-36 3NXP-A nrPDB 148 8e-36 1ETT-H nrPDB 148 8e-36 3K65-B nrPDB 147 1e-35 1FXY-A nrPDB 147 2e-35 2XRC-A nrPDB 146 3e-35 5KWM-A nrPDB 144 9e-35 2TLD-E nrPDB 144 1e-34 1PYT-D nrPDB 144 1e-34 4XDE-A nrPDB 144 1e-34 1KIG-H nrPDB 143 2e-34 1SGF-G nrPDB 143 2e-34 4KKD-A nrPDB 142 5e-34 6QHB-A nrPDB 141 7e-34 1C5M-D nrPDB 141 7e-34 4IW4-E nrPDB 141 8e-34 1VR1-H nrPDB 141 8e-34 2OCV-B nrPDB 140 1e-33 1SC8-U nrPDB 140 1e-33 5TO3-B nrPDB 139 4e-33 5O32-I nrPDB 139 4e-33 2V35-A nrPDB 139 4e-33 4NFE-A nrPDB 138 8e-33 2FMJ-A nrPDB 137 1e-32 1PQ7-A nrPDB 137 1e-32 4IGD-A nrPDB 137 2e-32 6BQM-A nrPDB 137 2e-32 5LHN-A nrPDB 137 2e-32 1A5I-A nrPDB 135 6e-32 1TON-A nrPDB 134 1e-31 2B9L-A nrPDB 134 1e-31 1BDA-A nrPDB 133 2e-31 1ELT-A nrPDB 133 2e-31 4DJZ-B nrPDB 133 2e-31 2OLG-A nrPDB 130 1e-30 3BEU-A nrPDB 129 3e-30 1YM0-A nrPDB 129 3e-30 1M9U-A nrPDB 129 4e-30 3I77-A nrPDB 129 5e-30 1SGF-A nrPDB 129 6e-30 1EQ9-A nrPDB 127 1e-29 4BXW-A nrPDB 127 2e-29 1NPM-A nrPDB 125 4e-29 1FDP-A nrPDB 125 4e-29 1SPJ-A nrPDB 125 5e-29 3QUM-P nrPDB 125 6e-29 1AZZ-A nrPDB 125 6e-29 2AIQ-A nrPDB 124 1e-28 2PSX-A nrPDB 124 2e-28 1Q3X-A nrPDB 123 2e-28 5FCR-A nrPDB 122 6e-28 1ZJK-A nrPDB 121 7e-28 1AO5-A nrPDB 121 1e-27 3BSQ-A nrPDB 120 1e-27 2XXL-A nrPDB 120 2e-27 1SI5-H nrPDB 120 2e-27 5MS3-A nrPDB 120 2e-27 4FXG-H nrPDB 118 1e-26 2ZKS-A nrPDB 117 1e-26 4E7N-A nrPDB 117 2e-26 4GSO-A nrPDB 116 3e-26 1GPZ-A nrPDB 115 4e-26 3S9B-A nrPDB 115 7e-26 1FON-A nrPDB 114 1e-25 2QY0-B nrPDB 114 1e-25 5ZFH-A nrPDB 114 1e-25 1MD7-A nrPDB 114 2e-25 4LK4-A nrPDB 112 6e-25 1BQY-A nrPDB 111 9e-25 1GVZ-A nrPDB 111 1e-24 1MZD-A nrPDB 111 1e-24 1ORF-A nrPDB 111 1e-24 2PKA-B nrPDB 109 4e-24 1EUF-A nrPDB 108 5e-24 2HLC-A nrPDB 107 1e-23 1FUJ-A nrPDB 106 3e-23 3RP2-A nrPDB 106 4e-23 2BDH-A nrPDB 104 1e-22 1OP0-A nrPDB 104 1e-22 5XRF-A nrPDB 104 1e-22 1ELV-A nrPDB 104 1e-22 5UBM-A nrPDB 104 1e-22 1FI8-A nrPDB 103 3e-22 4J1Y-A nrPDB 103 3e-22 3S69-A nrPDB 100 1e-21 2ASU-B nrPDB 100 3e-21 3G01-A nrPDB 100 3e-21 5LPF-A nrPDB 99 4e-21 1AKS-B nrPDB 96 5e-20 3TK9-A nrPDB 96 6e-20 2J8L-A nrPDB 95 8e-20 1IAU-A nrPDB 95 1e-19 1KYN-A nrPDB 95 1e-19 1NN6-A nrPDB 94 3e-19 3RU4-E nrPDB 91 2e-18 4X0L-C nrPDB 91 2e-18 4WJG-C nrPDB 90 3e-18 2JET-C nrPDB 90 4e-18 3VGC-B nrPDB 88 1e-17 4Q7Y-A nrPDB 88 1e-17 4F4O-C nrPDB 87 2e-17 1AE5-A nrPDB 87 2e-17 1PPF-E nrPDB 86 4e-17 2JET-B nrPDB 83 4e-16 1BBR-E nrPDB 81 1e-15 1RIW-B nrPDB 81 1e-15 1BBR-H nrPDB 80 4e-15 2HNT-F nrPDB 77 2e-14 5XW8-A nrPDB 75 7e-14 2RDL-A nrPDB 75 8e-14 3H7O-A nrPDB 72 5e-13 3H7T-A nrPDB 71 2e-12 1DLE-A nrPDB 70 3e-12 2OK5-A nrPDB 69 5e-12 2WIN-I nrPDB 69 8e-12 2I6S-A nrPDB 67 2e-11 3H5C-B nrPDB 62 1e-09 3F1S-B nrPDB 61 1e-09 2HNT-E nrPDB 49 6e-06 2HNT-C nrPDB 48 2e-05 2KAI-A nrPDB 41 0.001 1EPT-B nrPDB 38 0.012 4LG8-A nrPDB 31 1.8 5Z56-q nrPDB 30 3.5 5BPZ-A nrPDB 30 4.1 4KFN-A nrPDB 29 6.5 1HKY-A nrPDB 28 9.6 >6I44-A nrPDB Length = 627 Score = 1281 bits (3315), Expect = 0.0, Method: Compositional matrix adjust. Identities = 611/619 (98%), Positives = 612/619 (98%) Query: 20 GCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFL 79 GCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFL Sbjct: 9 GCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFL 68 Query: 80 KDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQK 139 KDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQK Sbjct: 69 KDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQK 128 Query: 140 RCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEI 199 RCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEI Sbjct: 129 RCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEI 188 Query: 200 GCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLK 259 GCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLK Sbjct: 189 GCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLK 248 Query: 260 TSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQ 319 TSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQ Sbjct: 249 TSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQ 308 Query: 320 ETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGD 379 ETCTKMIRCQFFTYSLLPEDCK E CKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGD Sbjct: 309 ETCTKMIRCQFFTYSLLPEDCKAEACKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGD 368 Query: 380 NSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGL 439 NSVCTTKTSTRIVGGT SSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGL Sbjct: 369 NSVCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGL 428 Query: 440 PLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQ 499 PLQDVWRIYSGIL LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPL YTEFQ Sbjct: 429 PLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQ 488 Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQ 559 KPICLPSKGDTSTIYTNCWVTGWGFS E GEIQNILQKVNIPLVTNEECQKRYQDYKITQ Sbjct: 489 KPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQ 548 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619 RMVCAGYKEGGKDACKGD+GGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD Sbjct: 549 RMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 608 Query: 620 WILEKTQSSDGKAQMQSPA 638 WILEKTQSSDGKAQMQSPA Sbjct: 609 WILEKTQSSDGKAQMQSPA 627 >2F83-A nrPDB Length = 625 Score = 783 bits (2021), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/627 (58%), Positives = 466/627 (74%), Gaps = 3/627 (0%) Query: 1 MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLF 60 MI Q +FI LF +VS C+TQL ++ F GGD+ +++TP+A+YCQ+ CT+HPRCLLF Sbjct: 1 MIFLYQVVHFI-LFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLF 59 Query: 61 SFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVD 120 +F S D + F C LKDSVT TLP+V+RT A+SG+S KQC HQISAC++DIY +D Sbjct: 60 TFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLD 119 Query: 121 MRGVNFNVSKVSSVEECQKRCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIK 180 M+G+N+N S S +ECQ+RCT+++ C FF+YAT+ F E+RN CLLK++ GTPT I Sbjct: 120 MKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRIT 179 Query: 181 VLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFF 240 L V SGFSLK CALS + C +IF + F+D ++ V+ PDAFVC ICT+HP CLFF Sbjct: 180 KLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFF 239 Query: 241 TFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGV 300 TF++ W ESQRN+CLLKTSESG PS+ + +SG+SL +C+ ++P CHS Y Sbjct: 240 TFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDT 299 Query: 301 DFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRI 360 DF GEEL++ K CQ+ CT +RCQFFTY+ C E K KC+L+LS +GSPT+I Sbjct: 300 DFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKI 359 Query: 361 AYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG 420 +G G SGY+LRLC DN CTTK RIVGGT S GEWPWQV+L QRHLCG Sbjct: 360 LHGRGGISGYTLRLCKM-DNE-CTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCG 417 Query: 421 GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG 480 GS+IG+QW+LTAAHCF G+ + R+YSGILN S+I +DT F ++EIIIH YK++E Sbjct: 418 GSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAES 477 Query: 481 NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI 540 +DIAL+KL+ +NYT+ Q+PICLPSKGD + IYT+CWVTGWG+ K + +IQN LQK I Sbjct: 478 GYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKI 537 Query: 541 PLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE 600 PLVTNEECQKRY+ +KIT +M+CAGY+EGGKDACKGDSGGPL CKHN +W LVGITSWGE Sbjct: 538 PLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE 597 Query: 601 GCARREQPGVYTKVAEYMDWILEKTQS 627 GCA+RE+PGVYT V EY+DWILEKTQ+ Sbjct: 598 GCAQRERPGVYTNVVEYVDWILEKTQA 624 >5TJX-A nrPDB Length = 263 Score = 546 bits (1406), Expect = e-155, Method: Compositional matrix adjust. Identities = 259/263 (98%), Positives = 259/263 (98%) Query: 376 NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 435 NTGDNSVCTTKTSTRIVGGT SSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC Sbjct: 1 NTGDNSVCTTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 60 Query: 436 FDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNY 495 FDGLPLQDVWRIYSGIL LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPL Y Sbjct: 61 FDGLPLQDVWRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEY 120 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY 555 TEFQKPI LPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY Sbjct: 121 TEFQKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY 180 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 615 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA Sbjct: 181 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 240 Query: 616 EYMDWILEKTQSSDGKAQMQSPA 638 EYMDWILEKTQSSDGKAQMQSPA Sbjct: 241 EYMDWILEKTQSSDGKAQMQSPA 263 >5GVT-A nrPDB Length = 250 Score = 428 bits (1100), Expect = e-120, Method: Compositional matrix adjust. Identities = 198/248 (79%), Positives = 223/248 (89%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGTN+S GEWPWQVSLQVKL +Q HLCGGS+IG QWVLTAAHCFDG+P DVWRIY G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 IL+LS+ITK+TP S+IKE+IIHQ YKVSEGN+DIALIKLQ PLNYTEFQKPI LPSK DT Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 +TIYTNCWVTGWG++KE+GE QNILQK IPLV NEECQK+Y+DY I ++M+CAGYKEGG Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGG 180 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDG 630 DACKGDSGGPLVCKH+G W+LVGITSWGEGCAR++QPGVYTKV+EYMDWILEKTQSSD Sbjct: 181 TDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQSSDV 240 Query: 631 KAQMQSPA 638 +A S A Sbjct: 241 RALETSSA 248 >6AOD-C nrPDB Length = 245 Score = 345 bits (886), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 157/237 (66%), Positives = 192/237 (81%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGT S GEWPWQV+L QRHLCGGS+IG+QW+LTAAHCF G+ + R+YSG Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 IL S+I +DT F ++EIIIH YK++E +DIAL+KL+ + YT+ Q+PI LPSKGD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 + IYT+CWVTGWG+ K + +IQN LQK IPLVTNEECQKRY+ +KIT +M+CAGY+EGG Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 KDACKGD+GGPL CKHN +W LVGITSWGEGCA+RE+PGVYT V EY+DWILEKTQ+ Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQA 237 >3W94-A nrPDB Length = 235 Score = 208 bits (530), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 101/235 (42%), Positives = 141/235 (60%), Gaps = 5/235 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIYS 449 +VGG N+ G WPW VSL + RH CG SLIG W+LTAAHC G W Sbjct: 1 VVGGVNAEKGAWPWMVSLHWR---GRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 450 GILNLSDI-TKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G+ S + +++ Q+ III++NY DIA++ LQ P+N+TE+ P+CL S+ Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 C++ GWG E G + +ILQ+ +PLV +ECQ+ +Y T M+CAGY E Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPE 177 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 GG D+C+GDSGGPL+C + W L+G+TS+G GC R E+PG Y +V+ + WI E Sbjct: 178 GGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAE 232 >3T2N-A nrPDB Length = 372 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 104/260 (40%), Positives = 154/260 (59%), Gaps = 23/260 (8%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVWRIY 448 RIVGG ++S G WPWQVSL+ HLCGGSL+ WVLTAAHCF + + WR++ Sbjct: 117 RIVGGRDTSLGRWPWQVSLRYDGA---HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 173 Query: 449 SGILNLSDITKDTPFS---QIKEIIIHQNY------KVSEGNHDIALIKLQAPLNYTEFQ 499 +G + + +P ++ ++ H Y E ++DIAL+ L +PL TE+ Sbjct: 174 AGA-----VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYI 228 Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-KRYQDYKIT 558 +P+CLP+ G C VTGWG ++ G+ +LQ+ +P+++N+ C + +I Sbjct: 229 QPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIK 288 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHN----GMWRLVGITSWGEGCARREQPGVYTKV 614 +M CAGY EGG DAC+GDSGGP VC+ + WRL GI SWG GCA ++PGVYTKV Sbjct: 289 PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV 348 Query: 615 AEYMDWILEKTQSSDGKAQM 634 +++ +WI + ++ + M Sbjct: 349 SDFREWIFQAIKTHSEASGM 368 >1P57-B nrPDB Length = 255 Score = 196 bits (497), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 103/259 (39%), Positives = 153/259 (59%), Gaps = 23/259 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVWRIYS 449 IVGG ++S G WPWQVSL+ HLCGGSL+ WVLTAAHCF + + WR+++ Sbjct: 1 IVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 450 GILNLSDITKDTPFS---QIKEIIIHQNY------KVSEGNHDIALIKLQAPLNYTEFQK 500 G + + +P ++ ++ H Y E ++DIAL+ L +PL TE+ + Sbjct: 58 GA-----VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQ 112 Query: 501 PICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-KRYQDYKITQ 559 P+CLP+ G C VTGWG ++ G+ +LQ+ +P+++N+ C + +I Sbjct: 113 PVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKP 172 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHN----GMWRLVGITSWGEGCARREQPGVYTKVA 615 +M CAGY EGG DAC+GDSGGP VC+ + WRL GI SWG GCA ++PGVYTKV+ Sbjct: 173 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS 232 Query: 616 EYMDWILEKTQSSDGKAQM 634 ++ +WI + ++ + M Sbjct: 233 DFREWIFQAIKTHSEASGM 251 >3DFJ-A nrPDB Length = 263 Score = 196 bits (497), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 97/244 (39%), Positives = 140/244 (57%), Gaps = 12/244 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I GG+++ G+WPWQVS+ + H+CGGSL+ QWVL+AAHCF ++ + + G Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 L ++D S +K+II H +Y DIAL++L P+ ++ + +PI LP+ + Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 511 STIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY-------QDYKITQRM 561 +C VTGWG + LQ++ +PL++ E C Y + + + + M Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDM 177 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 VCAGY EGGKDAC+GDSGGPL C G+W L GI SWG+ C R +PGVYT + Y WI Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 Query: 622 LEKT 625 K Sbjct: 238 QSKV 241 >4DGJ-A nrPDB Length = 235 Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 95/233 (40%), Positives = 145/233 (62%), Gaps = 5/233 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIYS 449 IVGG+++ G WPW V L R LCG SL+ W+++AAHC G L+ W Sbjct: 1 IVGGSDAKEGAWPWVVGLYYD---DRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 450 GILNLSDITKDTPFSQ-IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G+ S++T + I EI+I+ +Y ++DIA++ L+ +NYT++ +PI LP + Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 NC + GWG +G +ILQ+ ++PL++NE CQ++ +Y IT+ M+CAGY+E Sbjct: 118 QVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEE 177 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 GG D+C+GDSGGPL+C+ N W L G+TS+G CA +PGVY +V+ + +WI Sbjct: 178 GGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWI 230 >3E0N-B nrPDB Length = 271 Score = 195 bits (496), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 97/244 (39%), Positives = 140/244 (57%), Gaps = 12/244 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I GG+++ G+WPWQVS+ + H+CGGSL+ QWVL+AAHCF ++ + + G Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 L ++D S +K+II H +Y DIAL++L P+ ++ + +PI LP+ + Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 511 STIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY-------QDYKITQRM 561 +C VTGWG + LQ++ +PL++ E C Y + + + + M Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDM 177 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 VCAGY EGGKDAC+GDSGGPL C G+W L GI SWG+ C R +PGVYT + Y WI Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 Query: 622 LEKT 625 K Sbjct: 238 QSKV 241 >1EKB-B nrPDB Length = 235 Score = 194 bits (494), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 92/233 (39%), Positives = 147/233 (63%), Gaps = 5/233 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIYS 449 IVGG++S G WPW V+L + +CG SL+ W+++AAHC G ++ W+ Sbjct: 1 IVGGSDSREGAWPWVVALYFD---DQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 450 GILNLSDITKDTPFSQ-IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G+ S++T ++ I +I+I+ +Y N+DIA++ L+ +NYT++ +PICLP + Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 C + GWG +G ++LQ+ ++PL++NE+CQ++ +Y IT+ MVCAGY+ Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEA 177 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 GG D+C+GDSGGPL+C+ N W L G+TS+G CA +PGVY +V + +WI Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWI 230 >2F91-A nrPDB Length = 237 Score = 191 bits (486), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 96/234 (41%), Positives = 142/234 (60%), Gaps = 5/234 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTA-QRHLCGGSLIGHQWVLTAAHCFDGLPLQDV--WRI 447 IVGGT+++ GE+P+Q+S Q H CG S+ + +TA HC G ++ +I Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 +G L++S + +II+H+N+ + ++DI+L+KL L + + PI LP + Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 G T+T + VTGWG + E G ++LQKV +PLV++E+C+ Y +I M+CAG Sbjct: 121 GHTAT--GDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 EGGKD+C+GDSGGPL G L GI SWG GCAR PGVYT+V+ ++DWI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWI 232 >1FIW-A nrPDB Length = 290 Score = 179 bits (453), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 100/251 (39%), Positives = 142/251 (56%), Gaps = 13/251 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQV---KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 I+GG +++ G WPW VSLQ+ + H+CGGSL+ QW+LTAAHCF WR+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 448 YSGILNL---SDITKDTPFSQ--IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 G + ++ P + +++IIIH+ Y S +DIAL+K+ P+ F P Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 503 CLPS-KGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQK-RYQDYKITQ 559 CLP + + CWV GWGF +E +LQ+ + L+ C R+ + +I Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNG--MWRLVGITSWGEGCARREQPGVYTKVAEY 617 VCAGY EG D C+GDSGGPL+CK + + +VGITSWG GCAR ++PGVYT Y Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWSY 240 Query: 618 MDWILEKTQSS 628 ++WI K S+ Sbjct: 241 LNWIASKIGST 251 >1FIZ-A nrPDB Length = 263 Score = 178 bits (451), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 104/251 (41%), Positives = 139/251 (55%), Gaps = 13/251 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKL---TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 +VGG ++ G WPW VSLQ+ + + H CGG L+ WVLTAAHCF WR+ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 448 YSG---ILNLSDITKDTPFSQ--IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 G ++ S+ P + ++EIIIH+ Y +DIALIK+ P+ F P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 503 CLPS-KGDTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQK-RYQDYKITQ 559 CLP K CWVTGWG+ KEKG LQ+ + L+ E C R+ + +I Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNG--MWRLVGITSWGEGCARREQPGVYTKVAEY 617 VCAGY G D C+GDSGGPL+C+ + +VGITSWG GCAR ++PGVYT Y Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPY 240 Query: 618 MDWILEKTQSS 628 ++WI K S+ Sbjct: 241 LNWIASKIGSN 251 >1LTO-A nrPDB Length = 245 Score = 174 bits (441), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 96/241 (39%), Positives = 137/241 (56%), Gaps = 14/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + +WPWQVSL+V+ H CGGSLI QWVLTAAHC G ++D+ + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCL-GPDVKDLATLRVQ 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + +D + II+H + + + DIAL++L+ P+N + + LP +T Sbjct: 60 LREQHLYYQDQ-LLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASET 118 Query: 511 STIYTNCWVTGWGF--SKEKGEIQNILQKVNIPLVTNEECQKRYQ-------DYKITQR- 560 CWVTGWG + E L++V +P++ N C +Y D +I + Sbjct: 119 FPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDD 178 Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 M+CAG + +D+CKGDSGGPLVCK NG W G+ SW EGCA+ +PG+YT+V Y+DW Sbjct: 179 MLCAGNSQ--RDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLDW 236 Query: 621 I 621 I Sbjct: 237 I 237 >4Z6A-H nrPDB Length = 249 Score = 172 bits (437), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 98/247 (39%), Positives = 138/247 (55%), Gaps = 14/247 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG GE PWQV L L LCGG+LI WV++AAHCFD + WR Sbjct: 1 IVGGKVCPKGECPWQVLL---LVNGAQLCGGTLINTIWVVSAAHCFDKI---KNWRNLIA 54 Query: 451 ILNLSDITK---DTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 +L D+++ D ++ ++II Y NHDIAL++L P+ T+ P+CLP + Sbjct: 55 VLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPER 114 Query: 508 G---DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 564 T V+GWG ++G L +N+P + ++C+ Y KIT+ M CA Sbjct: 115 TFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPG-KITEYMFCA 173 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624 GY +G KD+CKGDSGGP + G W L GI SWG+GCA GVYT+V++Y++W L+K Sbjct: 174 GYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEW-LQK 232 Query: 625 TQSSDGK 631 S+ + Sbjct: 233 LMRSEPR 239 >3P8G-A nrPDB Length = 241 Score = 172 bits (436), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 97/244 (39%), Positives = 137/244 (56%), Gaps = 14/244 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF---DGLPLQDV--W 445 +VGGT++ GEWPWQVSL Q H+CG SLI W+++AAHC+ G D W Sbjct: 1 VVGGTDADEGEWPWQVSLHA--LGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 446 RIYSGILNLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 + G+ + S + P Q +K II H + ++DIAL++L+ P Y+ +PI Sbjct: 59 TAFLGLHDQSQ--RSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPI 116 Query: 503 CLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMV 562 CLP WVTGWG ++ G ILQK I ++ C+ +IT RM+ Sbjct: 117 CLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQ-QITPRMM 175 Query: 563 CAGYKEGGKDACKGDSGGPL-VCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 C G+ GG D+C+GDSGGPL + +G G+ SWG+GCA+R +PGVYT++ + DWI Sbjct: 176 CVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWI 235 Query: 622 LEKT 625 E T Sbjct: 236 KENT 239 >3LC3-A nrPDB Length = 235 Score = 172 bits (436), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 94/241 (39%), Positives = 141/241 (58%), Gaps = 13/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD-GLPLQDVWRIYS 449 +VGG ++ G++PWQV L K+ A CGGS++ +W++TAAHC + G+ + + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDA---FCGGSIVNEKWIVTAAHCVETGVKIT----VVA 53 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYK--VSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 G N+ + + II H NY +++ NHDIAL++L PL + PIC+ K Sbjct: 54 GEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADK 113 Query: 508 GDTSTI--YTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 T+ + + +V+GWG KG +LQ + +PLV C R + I M CAG Sbjct: 114 EYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCL-RSTKFTIYNNMFCAG 172 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 + EGG+D+C+GDSGGP V + G L GI SWGE CA + + G+YTKV+ Y++WI EKT Sbjct: 173 FHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKT 232 Query: 626 Q 626 + Sbjct: 233 K 233 >4MPW-A nrPDB Length = 245 Score = 172 bits (435), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 95/241 (39%), Positives = 136/241 (56%), Gaps = 14/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + +WPWQVSL+V H CGGSLI QWVLTAAHC G ++D+ + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + +D + II+H + ++ DIAL++L+ P+ + + LP +T Sbjct: 60 LREQHLYYQDQ-LLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASET 118 Query: 511 STIYTNCWVTGWGF--SKEKGEIQNILQKVNIPLVTNEECQKRYQ-------DYKITQR- 560 CWVTGWG + E+ L++V +P++ N C +Y D +I + Sbjct: 119 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 178 Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 M+CAG +D+C+GDSGGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+DW Sbjct: 179 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 236 Query: 621 I 621 I Sbjct: 237 I 237 >1X7A-C nrPDB Length = 235 Score = 171 bits (434), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 97/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD-GLPLQDVWRIYS 449 IVGG N+ G++PWQV L K+ A CGGS+I +WV+TAAHC + G+ + + + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDA---FCGGSIINEKWVVTAAHCIEPGVKIT----VVA 53 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYK--VSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 G N + + I H +Y V++ +HDIAL++L PL + PIC+ K Sbjct: 54 GEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADK 113 Query: 508 GDTSTI--YTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 T+ + + +V+GWG +G ILQ + +PLV C R + I M CAG Sbjct: 114 EYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCL-RSTKFTIYSNMFCAG 172 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 + EGGKD+C+GDSGGP V + G L GI SWGE CA + + G+YTKV+ Y++WI EKT Sbjct: 173 FHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKT 232 Query: 626 Q 626 + Sbjct: 233 K 233 >2CGA-A nrPDB Length = 245 Score = 171 bits (432), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 93/234 (39%), Positives = 128/234 (54%), Gaps = 10/234 (4%) Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448 +RIV G + G WPWQVSLQ K H CGGSLI WV+TAAHC G+ DV + Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDK--TGFHFCGGSLINENWVVTAAHC--GVTTSDV--VV 67 Query: 449 SGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 +G + ++ +I ++ + Y N+DI L+KL ++++ +CLPS Sbjct: 68 AGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSAS 127 Query: 509 DTSTIYTNCWVTGWGFSK-EKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 D T C TGWG ++ + LQ+ ++PL++N C K+Y KI M+CAG Sbjct: 128 DDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNC-KKYWGTKIKDAMICAGAS 186 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 G +C GDSGGPLVCK NG W LVGI SWG PGVY +V ++W+ Sbjct: 187 --GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWV 238 >5UGG-A nrPDB Length = 251 Score = 164 bits (416), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 88/248 (35%), Positives = 135/248 (54%), Gaps = 12/248 (4%) Query: 376 NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 435 + G V K R+VGG + WPWQVSL+ + H CGG+LI +WVLTAAHC Sbjct: 7 DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGM--HFCGGTLISPEWVLTAAHC 64 Query: 436 FDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNY 495 + P +++ G ++ ++ + + K DIAL+KL +P Sbjct: 65 LEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLSSPAVI 118 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQK-RYQ 553 T+ P CLPS T C++TGWG + +G +L++ +P++ N+ C + + Sbjct: 119 TDKVIPACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFL 176 Query: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613 + ++ +CAG+ GG D+C+GDSGGPLVC + L G+TSWG GCAR +PGVY + Sbjct: 177 NGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVR 236 Query: 614 VAEYMDWI 621 V+ ++ WI Sbjct: 237 VSRFVTWI 244 >2OQ5-A nrPDB Length = 232 Score = 164 bits (416), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 96/238 (40%), Positives = 127/238 (53%), Gaps = 11/238 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGT GEWPWQ SLQ + H CG +LI W+++AAHCF W G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGS---HRCGATLINATWLVSAAHCFTTYKNPARWTASFG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + I ++ II+H+ YK ++DI+L +L +P+ YT +CLP Sbjct: 58 VT----IKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYE 113 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ--KRYQDYKITQRMVCAGYKE 568 +VTG+G K G QN L++ + L+ C + Y D IT RM+CAG E Sbjct: 114 FQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYND-AITPRMLCAGSLE 172 Query: 569 GGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 G DAC+GDSGGPLV +W L GI SWG+ CA+ +PGVYT+V DWI KT Sbjct: 173 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKT 230 >5FXL-A nrPDB Length = 246 Score = 164 bits (415), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 91/240 (37%), Positives = 138/240 (57%), Gaps = 17/240 (7%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +IVGG P+QVSL + H CGGSLI QWV++AAHC+ + ++ Sbjct: 23 KIVGGYTCGANTVPYQVSLN----SGYHFCGGSLINSQWVVSAAHCY-----KSGIQVRL 73 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N++ + + F + I+H +Y + N+DI LIKL++ + I LP+ Sbjct: 74 GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTS-- 131 Query: 510 TSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 ++ T C ++GWG +K G ++L+ + P++++ C+ Y +IT M CAGY E Sbjct: 132 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPG-QITSNMFCAGYLE 190 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 GGKD+C+GDSGGP+VC +L GI SWG GCA++ +PGVYTKV Y+ WI + S+ Sbjct: 191 GGKDSCQGDSGGPVVCSG----KLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >4DUR-A nrPDB Length = 791 Score = 163 bits (413), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 88/246 (35%), Positives = 134/246 (54%), Gaps = 12/246 (4%) Query: 378 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD 437 G V K R+VGG + WPWQVSL+ + H CGG+LI +WVLTAAHC + Sbjct: 549 GKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGM--HFCGGTLISPEWVLTAAHCLE 606 Query: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497 P +++ G ++ ++ + + K DIAL+KL +P T+ Sbjct: 607 KSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLSSPAVITD 660 Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQK-RYQDY 555 P CLPS T C++TGWG + +G +L++ +P++ N+ C + + + Sbjct: 661 KVIPACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNG 718 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 615 ++ +CAG+ GG D+C+GDSGGPLVC + L G+TSWG GCAR +PGVY +V+ Sbjct: 719 RVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVS 778 Query: 616 EYMDWI 621 ++ WI Sbjct: 779 RFVTWI 784 >1F7Z-A nrPDB Length = 233 Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 96/239 (40%), Positives = 135/239 (56%), Gaps = 17/239 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG P+QVSL + H CGGSLI QWV++AAHC+ + ++ G Sbjct: 11 IVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCY-----KSRIQVRLG 61 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N++ + + F +II H N+ N+DI LIKL +P+ + LPS Sbjct: 62 EHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS--C 119 Query: 511 STIYTNCWVTGWGFSKEKGEIQ-NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + T C ++GWG + G + ++LQ ++ PL+ +C+ Y KIT MVC G+ EG Sbjct: 120 APAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPG-KITDNMVCVGFLEG 178 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 GKD+C+GDSGGP+VC NG L GI SWG GCA + PGVYTKV Y+DWI + ++ Sbjct: 179 GKDSCQGDSGGPVVC--NG--ELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 92/240 (38%), Positives = 137/240 (57%), Gaps = 17/240 (7%) Query: 385 TKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 444 T +IVGG + P+QVSL + H CGGSLI QWV++AAHC+ + Sbjct: 3 TDDDDKIVGGYTCAANSIPYQVSLN----SGSHFCGGSLINSQWVVSAAHCY-----KSR 53 Query: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504 ++ G N+ + + F +II H N+ + ++DI LIKL +P + L Sbjct: 54 IQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 113 Query: 505 PSKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQDYKITQRMVC 563 P + T C ++GWG +K G ++LQ + P++++ C+ Y +IT M+C Sbjct: 114 PRS--CAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPG-QITGNMIC 170 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 G+ EGGKD+C+GDSGGP+VC NG +L GI SWG GCA++ +PGVYTKV Y++WI + Sbjct: 171 VGFLEGGKDSCQGDSGGPVVC--NG--QLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQ 226 >1YC0-A nrPDB Length = 283 Score = 160 bits (406), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 90/244 (36%), Positives = 134/244 (54%), Gaps = 11/244 (4%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RI+GG++S G PW ++ + + C GSL+ WV++AAHCF P +D + Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 90 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKV-SEGNHDIALIKLQAP----LNYTEFQKPICL 504 G + T T I++ I + Y V + +HD+ LI+L+ ++F +PICL Sbjct: 91 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 150 Query: 505 PSKGDTSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMV 562 P G T C + GWG E + L++ +PLV + +C I+ M+ Sbjct: 151 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 210 Query: 563 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWIL 622 CAGY + DAC+GDSGGPL C+ NG+ L GI SWG+GC R +PGVYT+VA Y+DWI Sbjct: 211 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 270 Query: 623 EKTQ 626 ++ + Sbjct: 271 DRIR 274 >2R0L-A nrPDB Length = 248 Score = 158 bits (399), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 89/243 (36%), Positives = 133/243 (54%), Gaps = 11/243 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG++S G PW ++ + + C GSL+ WV++AAHCF P +D + G Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKV-SEGNHDIALIKLQAP----LNYTEFQKPICLP 505 + T T I++ I + Y V + +HD+ LI+L+ ++F +PICLP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 506 SKGDTSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVC 563 G T C + GWG E + L++ +PLV + +C I+ M+C Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 AGY + DAC+GDSGGPL C+ NG+ L GI SWG+GC R +PGVYT+VA Y+DWI + Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 236 Query: 624 KTQ 626 + + Sbjct: 237 RIR 239 >1UTJ-A nrPDB Length = 242 Score = 155 bits (392), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 91/238 (38%), Positives = 122/238 (51%), Gaps = 16/238 (6%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +IVGG P+ QV L + H CGGSL+ WV++AAHC+ + + Sbjct: 20 KIVGGYECK----PYSQPHQVSLNSGYHFCGGSLVNENWVVSAAHCY-----KSRVEVRL 70 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N+ F +I H NY ++DI LIKL P + +P+ LP+ Sbjct: 71 GEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTS-- 128 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + T C V+GWG + N LQ +NIP+++ +C Y IT M CAGY EG Sbjct: 129 CAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPG-MITNAMFCAGYLEG 187 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 GKD+C+GDSGGP+VC NG L G+ SWG GCA PGVY KV + DW+ S Sbjct: 188 GKDSCQGDSGGPVVC--NG--ELQGVVSWGYGCAEPGNPGVYAKVCIFNDWLTSTMAS 241 >1A0J-A nrPDB Length = 223 Score = 154 bits (390), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 88/225 (39%), Positives = 127/225 (56%), Gaps = 14/225 (6%) Query: 406 VSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQ 465 S Q L + H CGGSLI WV++AAHC+ + ++ G N++ F Sbjct: 12 ASYQASLQSGYHFCGGSLISSTWVVSAAHCY-----KSRIQVRLGEHNIAVNEGTEQFID 66 Query: 466 IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG-F 524 ++I+H +Y ++DI LIKL P + + + LPS +S T C V+GWG Sbjct: 67 SVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASSG--TRCLVSGWGNL 124 Query: 525 SKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVC 584 S + L+ +++P++++ C Y +IT M CAG+ EGGKD+C+GDSGGP+VC Sbjct: 125 SGSSSNYPDTLRCLDLPILSSSSCNSAYPG-QITSNMFCAGFMEGGKDSCQGDSGGPVVC 183 Query: 585 KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 NG +L G+ SWG GCA+R +PGVYTKV Y WI T SS+ Sbjct: 184 --NG--QLQGVVSWGYGCAQRNKPGVYTKVCNYRSWI-SSTMSSN 223 >3F6U-H nrPDB Length = 240 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 94/241 (39%), Positives = 132/241 (54%), Gaps = 17/241 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 ++ G + G+ PWQV L L +++ L CG LI WVLTAAHC D + Sbjct: 1 LIDGKMTRRGDSPWQVVL---LDSKKKLACGAVLIHPSWVLTAAHCMDE---SKKLLVRL 54 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG- 508 G +L K IKE+ +H NY S ++DIAL+ L P ++ PICLP G Sbjct: 55 GEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGL 114 Query: 509 ---DTSTIYTNCWVTGWGF--SKEKGEIQN---ILQKVNIPLVTNEECQKRYQDYKITQR 560 + + VTGWG+ S+EK +N +L + IP+V + EC + + +++ Sbjct: 115 AERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNM-VSEN 173 Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 M+CAG +DAC+GDSGGP+V +G W LVG+ SWGEGC GVYTKV+ Y+DW Sbjct: 174 MLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDW 233 Query: 621 I 621 I Sbjct: 234 I 234 >1BRU-P nrPDB Length = 241 Score = 152 bits (385), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 95/245 (38%), Positives = 142/245 (57%), Gaps = 25/245 (10%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGG ++ WPWQVSLQ + Q RH CGG+L+ WVLTAAHC R Y Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS------RTYR 54 Query: 450 GILNLSDITKDTPFS---QIKEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPIC 503 +L ++ + P S ++ ++++HQ++ ++S GN DIAL+KL +P++ T+ + C Sbjct: 55 VVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGN-DIALLKLASPVSLTDKIQLGC 113 Query: 504 LPSKGDTSTIYTN---CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQ 559 LP+ G TI N C+VTGWG + G +ILQ+ + +V C K + + Sbjct: 114 LPAAG---TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWGE--GCARREQPGVYTKVAE 616 M+CAG +G +C GDSGGPL C+ NG W++ GI S+G GC +P V+T+V+ Sbjct: 171 NMICAG-GDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 617 YMDWI 621 Y+DWI Sbjct: 230 YIDWI 234 >1MKW-K nrPDB Length = 308 Score = 151 bits (382), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 100/253 (39%), Positives = 136/253 (53%), Gaps = 23/253 (9%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RIV G ++ G PWQV L + + Q LCG SLI +WVLTAAHC P + + Sbjct: 49 RIVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 107 Query: 450 GILNLSDIT------KDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPI 502 ++ + + K S + +I IH Y E + DIAL+KL+ P+ +++ P+ Sbjct: 108 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 167 Query: 503 CLPSKGDTSTIYTNCW---VTGWGFSKEK-----GEIQ-NILQKVNIPLVTNEECQKRYQ 553 CLP K + + + VTGWG +E E+Q ++LQ VN+PLV C+ + Sbjct: 168 CLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR 227 Query: 554 DYKITQRMVCAGYKEG-GK--DACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARREQP 608 +IT M CAGYK G GK DAC+GDSGGP V K +N W +GI SWGEGC R + Sbjct: 228 -IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKY 286 Query: 609 GVYTKVAEYMDWI 621 G YT V WI Sbjct: 287 GFYTHVFRLKKWI 299 >2EEK-A nrPDB Length = 220 Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 83/215 (38%), Positives = 120/215 (55%), Gaps = 12/215 (5%) Query: 409 QVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKE 468 QV L + H CGGSL+ WV++AAHC+ + V R+ G ++ + Sbjct: 15 QVSLNSGYHFCGGSLVSKDWVVSAAHCY-----KSVLRVRLGEHHIRVNEGTEQYISSSS 69 Query: 469 IIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEK 528 +I H NY N+DI LIKL P ++ + LP+ + + T C V+GWG + Sbjct: 70 VIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPT--ECAADATMCTVSGWGNTMSS 127 Query: 529 GEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG 588 + LQ +++P++++ +C Y ITQ M CAGY EGGKD+C+GDSGGP+VC NG Sbjct: 128 VADGDKLQCLSLPILSHADCANSYPG-MITQSMFCAGYLEGGKDSCQGDSGGPVVC--NG 184 Query: 589 MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 + L G+ SWG GCA R+ PGVY KV W+ + Sbjct: 185 V--LQGVVSWGYGCAERDHPGVYAKVCVLSGWVRD 217 >4WWY-A nrPDB Length = 224 Score = 150 bits (380), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 90/232 (38%), Positives = 129/232 (55%), Gaps = 17/232 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG N P+QVSL + H CGGSLI QWV++A HC+ + ++ G Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCY-----KSRIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + F +II H Y N+DI LIKL + I LP+ Sbjct: 52 EHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPA 111 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + T C ++GWG + G + + LQ ++ P+++ +C+ Y KIT M C G+ EG Sbjct: 112 TG--TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPG-KITSNMFCVGFLEG 168 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 GKD+C+ DSGGP+VC NG +L G+ SWG+GCA++ +PGVYTKV Y+ WI Sbjct: 169 GKDSCQRDSGGPVVC--NG--QLQGVVSWGDGCAQKNKPGVYTKVYNYVKWI 216 >5C67-A nrPDB Length = 224 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 91/232 (39%), Positives = 129/232 (55%), Gaps = 17/232 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG P+QVSL + H CGGSLI QWV++AAHC+ + ++ G Sbjct: 1 IVGGYTCEENSLPYQVSLN----SGSHFCGGSLISEQWVVSAAHCY-----KTRIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + F +II H Y ++DI LIKL +P I LP+ Sbjct: 52 EHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPA 111 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + T C ++GWG + G + + L+ ++ P++T EC+ Y KIT M C G+ EG Sbjct: 112 AG--TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG-KITNSMFCVGFLEG 168 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 GKD+C+ D+GGP+VC NG +L G+ SWG GCA + +PGVYTKV Y+DWI Sbjct: 169 GKDSCQRDAGGPVVC--NG--QLQGVVSWGHGCAWKNRPGVYTKVYNYVDWI 216 >4H4F-A nrPDB Length = 249 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 94/242 (38%), Positives = 135/242 (55%), Gaps = 10/242 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGG ++ WPWQ+SLQ +K RH CGG+LI +VLTAAHC +R+ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISN---TRTYRVAV 57 Query: 450 GILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G NL + + + F + I +H+ + +DIALIKL + ++ + CLP K Sbjct: 58 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGYK 567 C+VTGWG G I + LQ+ P+V + C + + +++ + MVCAG Sbjct: 118 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 176 Query: 568 EGGKDACKGDSGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILEK 624 +G AC GDSGGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+DWI EK Sbjct: 177 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 236 Query: 625 TQ 626 Q Sbjct: 237 MQ 238 >4NZQ-A nrPDB Length = 557 Score = 148 bits (374), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 97/254 (38%), Positives = 138/254 (54%), Gaps = 25/254 (9%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RIV G+++ G PWQV L + + Q LCG SLI +WVLTAAHC P + Sbjct: 298 RIVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 356 Query: 450 GILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPI 502 ++ + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ P+ Sbjct: 357 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 416 Query: 503 CLPSKGDTSTIYTNCW---VTGWGFSKE-------KGEIQNILQKVNIPLVTNEECQKRY 552 CLP + +++ + VTGWG KE KG+ ++LQ VN+P+V C+ Sbjct: 417 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQ-PSVLQVVNLPIVERPVCKDST 475 Query: 553 QDYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQ 607 + +IT M CAGYK EG + DAC+GDSGGP V K N W +GI SWGEGC R + Sbjct: 476 R-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 534 Query: 608 PGVYTKVAEYMDWI 621 G YT V WI Sbjct: 535 YGFYTHVFRLKKWI 548 >3NXP-A nrPDB Length = 424 Score = 148 bits (373), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 97/254 (38%), Positives = 138/254 (54%), Gaps = 25/254 (9%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RIV G+++ G PWQV L + + Q LCG SLI +WVLTAAHC P + Sbjct: 165 RIVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 223 Query: 450 GILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPI 502 ++ + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ P+ Sbjct: 224 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 283 Query: 503 CLPSKGDTSTIYTNCW---VTGWGFSKE-------KGEIQNILQKVNIPLVTNEECQKRY 552 CLP + +++ + VTGWG KE KG+ ++LQ VN+P+V C+ Sbjct: 284 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQ-PSVLQVVNLPIVERPVCKDST 342 Query: 553 QDYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQ 607 + +IT M CAGYK EG + DAC+GDSGGP V K N W +GI SWGEGC R + Sbjct: 343 R-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 401 Query: 608 PGVYTKVAEYMDWI 621 G YT V WI Sbjct: 402 YGFYTHVFRLKKWI 415 >1ETT-H nrPDB Length = 259 Score = 148 bits (373), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 99/252 (39%), Positives = 135/252 (53%), Gaps = 23/252 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G ++ G PWQV L + + Q LCG SLI +WVLTAAHC P + + Sbjct: 1 IVEGQDAEVGLSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 451 ILNLSDIT------KDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 ++ + + K S + +I IH Y E + DIAL+KL+ P+ +++ P+C Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 504 LPSKGDTSTIYTNCW---VTGWGFSKEK-----GEIQ-NILQKVNIPLVTNEECQKRYQD 554 LP K + + + VTGWG +E E+Q ++LQ VN+PLV C+ + Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR- 178 Query: 555 YKITQRMVCAGYKEG-GK--DACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARREQPG 609 +IT M CAGYK G GK DAC+GDSGGP V K +N W +GI SWGEGC R + G Sbjct: 179 IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG 238 Query: 610 VYTKVAEYMDWI 621 YT V WI Sbjct: 239 FYTHVFRLKKWI 250 >3K65-B nrPDB Length = 308 Score = 147 bits (371), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 97/270 (35%), Positives = 143/270 (52%), Gaps = 25/270 (9%) Query: 374 LCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAA 433 L + + + + RIV G+++ G PWQV L + + Q LCG SLI +WVLTAA Sbjct: 33 LEDKTERELLESYIDGRIVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAA 91 Query: 434 HCFDGLPLQDVWRIYSGILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIAL 486 HC P + ++ + ++ S +++I IH Y E + DIAL Sbjct: 92 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 151 Query: 487 IKLQAPLNYTEFQKPICLPSKGDTSTIYTNCW---VTGWGFSKE-------KGEIQNILQ 536 +KL+ P+ ++++ P+CLP + +++ + VTGWG KE KG+ ++LQ Sbjct: 152 MKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQ-PSVLQ 210 Query: 537 KVNIPLVTNEECQKRYQDYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCKH--NGMWR 591 VN+P+V C+ + +IT M CAGYK EG + DAC+GD+GGP V K N W Sbjct: 211 VVNLPIVERPVCKDSTR-IRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWY 269 Query: 592 LVGITSWGEGCARREQPGVYTKVAEYMDWI 621 +GI SWGEGC R + G YT V WI Sbjct: 270 QMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 299 >1FXY-A nrPDB Length = 228 Score = 147 bits (370), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 84/232 (36%), Positives = 130/232 (56%), Gaps = 13/232 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG N GE PWQ L + CGG+++ ++LTAAHC L +++ G Sbjct: 1 IVGGYNCKDGEVPWQALLINE--ENEGFCGGTILSEFYILTAAHC---LYQAKRFKVRVG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N +++ +I H + + DIA+++L+ P+ + P LP+ Sbjct: 56 DRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPA 115 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + T C ++GWG + G + + LQ ++ P+++ +C+ Y KIT M C G+ EG Sbjct: 116 TG--TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPG-KITSNMFCVGFLEG 172 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 GKD+C+GDSGGP+VC NG +L G+ SWG+GCA++ +PGVYTKV Y+ WI Sbjct: 173 GKDSCQGDSGGPVVC--NG--QLQGVVSWGDGCAQKNKPGVYTKVYNYVKWI 220 >2XRC-A nrPDB Length = 565 Score = 146 bits (368), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 90/238 (37%), Positives = 127/238 (53%), Gaps = 13/238 (5%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RIVGG + G+ PWQV+++ A CGG IG W+LTAAHC ++I++ Sbjct: 321 RIVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHR-YQIWT 376 Query: 450 GILN-LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKP----ICL 504 +++ + K + II H+NY +DIALI+++ N + + P C+ Sbjct: 377 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 436 Query: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 564 P C V+GWG K+ + + LQ + L++N C K Y + + M CA Sbjct: 437 PWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECA 493 Query: 565 GYKEGGKDACKGDSGGPLVC-KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 G +G DACKGDSGGPLVC N + + G+ SWGE C + E PGVYTKVA Y DWI Sbjct: 494 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 551 >5KWM-A nrPDB Length = 230 Score = 144 bits (364), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 84/238 (35%), Positives = 135/238 (56%), Gaps = 15/238 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG +++ + P+ V+L V Q+ CGG+L V+TAAHC G D+ + SG Sbjct: 1 IVGGEDANVQDHPFTVAL-VTPDGQQ-FCGGTLAAPNKVVTAAHCTVGSQPADI-NVVSG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +S + + S++ + +H Y+ + D++++ L+AP+ + PI L D Sbjct: 58 RTVMS--SNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVK----EAPIELAKADDA 111 Query: 511 S-TIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T + GWG + E G+ + LQK +P+ +++ C++ Y +Y MVCAG EG Sbjct: 112 GYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEY-TPDAMVCAGVPEG 170 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 G D C+GDSGGP+V + +L+G+TSWGEGCAR +PGVY +V Y D ++E+ + Sbjct: 171 GVDTCQGDSGGPMVVNN----KLIGVTSWGEGCARPGKPGVYARVGAYYDVLMEQINA 224 >2TLD-E nrPDB Length = 220 Score = 144 bits (364), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 89/238 (37%), Positives = 133/238 (55%), Gaps = 20/238 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG P+QVSL + H CGGSLI QWV++AAHC+ + ++ G Sbjct: 1 IVGGYTCGANTVPYQVSLN----SGYHFCGGSLINSQWVVSAAHCY-----KSGIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N++ + + F + I+H +Y + N+DI LIKL++ + I LP+ Sbjct: 52 EDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SC 109 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 ++ T C ++GWG +K G ++L+ + P++++ C+ Y +IT M CAG EG Sbjct: 110 ASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPG-QITSNMFCAGL-EG 167 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 G D+C+GDSGGP+VC +L GI SWG GCA+ +PGVYTKV Y+ WI + S Sbjct: 168 G-DSCQGDSGGPVVCSG----KLQGIVSWGSGCAKN-KPGVYTKVCNYVSWIKQTIAS 219 >1PYT-D nrPDB Length = 251 Score = 144 bits (363), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 92/244 (37%), Positives = 132/244 (54%), Gaps = 9/244 (3%) Query: 388 STRIVGGTNSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 446 S R+VGG ++ WPWQ+SLQ ++ RH CGG+LI VLTAAHC +R Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTL---TYR 67 Query: 447 IYSGILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 505 + G NL + + + + I +H+ + +DIALIKL + + + CLP Sbjct: 68 VALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLP 127 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCA 564 S+G C+VTGWG G I LQ+ P+V C +R + + + MVCA Sbjct: 128 SEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCA 187 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG--CARREQPGVYTKVAEYMDWIL 622 G +G AC GDSGGPL C+ +G W + GI S+G G C ++P V+T+V+ Y+DWI Sbjct: 188 G-GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWIN 246 Query: 623 EKTQ 626 +K Q Sbjct: 247 QKLQ 250 >4XDE-A nrPDB Length = 257 Score = 144 bits (363), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 88/247 (35%), Positives = 122/247 (49%), Gaps = 14/247 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG + G P+ +L + C GSLI WVLTAAHC P + + G Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS----FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLN-----YTEFQKPICLP 505 + + ++ +H+ + HD+AL++LQ + + + +P+ LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQK-RYQDYKITQRMVC 563 S + T C V GWG E E + LQ+ +P ++ E C I M+C Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLC 178 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWR---LVGITSWGEGCARREQPGVYTKVAEYMDW 620 AG+ EGG DAC+GDSGGPLVC+ R L GI SWG GC R +PGVYT VA Y+ W Sbjct: 179 AGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAW 238 Query: 621 ILEKTQS 627 I E T S Sbjct: 239 IREHTVS 245 >1KIG-H nrPDB Length = 241 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 130/245 (53%), Gaps = 9/245 (3%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + + GE PWQ L + CGG+++ +VLTAAHC L + + G Sbjct: 1 IVGGRDCAEGECPWQALLVNE--ENEGFCGGTILNEFYVLTAAHC---LHQAKRFTVRVG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG-D 509 N + +++ + H + + DIA+++L+ P+ + P CLP K Sbjct: 56 DRNTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWA 115 Query: 510 TSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 +T+ T V+G+G + EKG + + L+ + +P V C K + IT M CAGY Sbjct: 116 EATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTC-KLSSSFTITPNMFCAGYD 174 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +DAC+GDSGGP V + + + GI SWGEGCAR+ + GVYTKV+ ++ WI + ++ Sbjct: 175 TQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKA 234 Query: 628 SDGKA 632 G A Sbjct: 235 RAGAA 239 >1SGF-G nrPDB Length = 237 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 92/247 (37%), Positives = 138/247 (55%), Gaps = 34/247 (13%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PW V++ ++LCGG L+ WVLTAAHC+D D ++++ G Sbjct: 1 IVGGFKCEKNSQPWHVAV---YRYTQYLCGGVLLDPNWVLTAAHCYD-----DNYKVWLG 52 Query: 451 ILNLSDITKDTPFSQ---IKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYT 496 NL KD P +Q + + I H + +S + ++D+ L++L P + T Sbjct: 53 KNNL---FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADIT 109 Query: 497 EFQKPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDY 555 + KPI LP+ + + + C +GWG + K + + L VN+ L+ NE+C K + + Sbjct: 110 DTVKPITLPT--EEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIE- 166 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKV 614 K+T M+CAG +GGKD CKGDSGGPL+C +G+ L GITSWG C + PGVYTK+ Sbjct: 167 KVTDAMLCAGEMDGGKDTCKGDSGGPLIC--DGV--LQGITSWGHTPCGEPDMPGVYTKL 222 Query: 615 AEYMDWI 621 ++ WI Sbjct: 223 NKFTSWI 229 >4KKD-A nrPDB Length = 433 Score = 142 bits (358), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 92/290 (31%), Positives = 146/290 (50%), Gaps = 35/290 (12%) Query: 369 GYSLRLC--NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQ----RHLCGGS 422 G SL C G S RI+GG N+ G +PWQ + V+ T++ + G+ Sbjct: 131 GRSLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGA 190 Query: 423 LIGHQWVLTAAHCFDG-------LPL-QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQN 474 L+ W+LTAAH +P+ ++ +Y G+ ++ D + S + +++H + Sbjct: 191 LLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAAR-VVLHPD 249 Query: 475 YKVSEGNHDIALIKLQAPLNYTEFQKPICLPS-KGDTSTIYTNCWVTGWGFSKEKGEIQ- 532 + + NHDIAL++LQ P+ P+CLP + + + V GWG S + Sbjct: 250 FNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDE 309 Query: 533 ----------NILQKVNIPLVTNEECQKRYQ----DYKITQRMVCAGYKEGGKDACKGDS 578 ++LQ V +P+V + EC+ Y+ +Y +T+ M CAGY EGGKD C GDS Sbjct: 310 IISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDS 369 Query: 579 GGPLVCKHN--GMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILEK 624 G V + W + G+ SWG E C ++ GVYTKV+ Y+DW+ E+ Sbjct: 370 GEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQ 419 >6QHB-A nrPDB Length = 223 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 87/226 (38%), Positives = 126/226 (55%), Gaps = 17/226 (7%) Query: 403 PWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTP 462 P+Q +L T+ LCGG LI WVLTAAHC + +++ G NL Sbjct: 13 PYQAAL---YTSGHLLCGGVLIHPLWVLTAAHCK-----KPNLQVFLGKHNLGQQESSQE 64 Query: 463 FSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGW 522 S + +IH +Y + + DI L++L P +E +P LP + D S T+C + GW Sbjct: 65 QSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTTSCHILGW 122 Query: 523 GFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPL 582 G + + G+ + +Q I LV+ EEC+ Y +ITQ M+CAG ++ GKD+C+GDSGGPL Sbjct: 123 GKTAD-GDFPDTIQCAYIHLVSREECEHAYPG-QITQNMLCAGDEKYGKDSCQGDSGGPL 180 Query: 583 VCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQS 627 VC + L G+ SWG C +E+PGVYT V Y +WI + Q+ Sbjct: 181 VCGDH----LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 222 >1C5M-D nrPDB Length = 255 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 86/252 (34%), Positives = 132/252 (52%), Gaps = 12/252 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG GE PWQ L + CGG+++ ++LTAAHC L +++ G Sbjct: 1 IVGGQECKDGECPWQALLINE--ENEGFCGGTILSEFYILTAAHC---LYQAKRFKVRVG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG-D 509 N +++ +I H + + DIA+++L+ P+ + P CLP + Sbjct: 56 DRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWA 115 Query: 510 TSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 ST+ T V+G+G + EKG L+ + +P V C K + ITQ M CAGY Sbjct: 116 ESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSC-KLSSSFIITQNMFCAGYD 174 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +DAC+GDSGGP V + + + GI SWGEGCAR+ + G+YTKV ++ WI +++ Sbjct: 175 TKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWI-DRSMK 233 Query: 628 SDG--KAQMQSP 637 + G KA+ +P Sbjct: 234 TRGLPKAKSHAP 245 >4IW4-E nrPDB Length = 279 Score = 141 bits (356), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 86/266 (32%), Positives = 139/266 (52%), Gaps = 33/266 (12%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQ----RHLCGGSLIGHQWVLTAAHCFDG-------L 439 I+GG N+ G +PWQ + V+ T++ + G+L+ W+LTAAH + Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 440 PL-QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEF 498 P+ ++ +Y G+ ++ D + S +++H ++ + NHDIAL++LQ P+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 499 QKPICLPS-KGDTSTIYTNCWVTGWGFSKEKGEIQ-----------NILQKVNIPLVTNE 546 P+CLP + + + V GWG S + ++LQ V +P+V + Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 547 ECQKRYQ----DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHN--GMWRLVGITSWG- 599 EC+ Y+ +Y +T+ M CAGY EGGKD C GDSGG V + W + G+ SWG Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 600 -EGCARREQPGVYTKVAEYMDWILEK 624 E C ++ GVYTKV+ Y+DW+ E+ Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQ 265 >1VR1-H nrPDB Length = 261 Score = 141 bits (356), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 96/256 (37%), Positives = 136/256 (53%), Gaps = 27/256 (10%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLT---AQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 IV G+++ G PWQV L K +R LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 448 YSGILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQK 500 ++ + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 501 PICLPSKGDTSTIYTNCW---VTGWGFSKE-------KGEIQNILQKVNIPLVTNEECQK 550 P+CLP + +++ + VTGWG KE KG+ ++LQ VN+P+V C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQ-PSVLQVVNLPIVERPVCKD 179 Query: 551 RYQDYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARR 605 + +IT M CA YK EG + DAC+GDSGGP V K N W +GI SWGEGC R Sbjct: 180 STR-IRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 238 Query: 606 EQPGVYTKVAEYMDWI 621 + G YT V WI Sbjct: 239 GKYGFYTHVFRLKKWI 254 >2OCV-B nrPDB Length = 259 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 93/252 (36%), Positives = 134/252 (53%), Gaps = 23/252 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G ++ G PWQV L + + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGWDAEKGIAPWQVML-FRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 451 ILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 ++ + ++ S +++I +H Y E + DIAL+KL+ P+ ++++ P+C Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 504 LPSKGDTSTIYTNCW---VTGWGFSKEK-----GEIQ-NILQKVNIPLVTNEECQKRYQD 554 LP K +++ + VTGWG +E EIQ ++LQ VN+P+V C+ + Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTR- 178 Query: 555 YKITQRMVCAGYKEGGK---DACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARREQPG 609 +IT M CAG+K DAC+GDSGGP V K N W +GI SWGEGC R+ + G Sbjct: 179 IRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYG 238 Query: 610 VYTKVAEYMDWI 621 YT V WI Sbjct: 239 FYTHVFRLKAWI 250 >1SC8-U nrPDB Length = 262 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 81/253 (32%), Positives = 140/253 (55%), Gaps = 10/253 (3%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSL--QVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPL 441 T + +I+GG ++ PW ++ + + + ++CGGSLI WV++A HCF P Sbjct: 9 TLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPK 68 Query: 442 QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH--DIALIKLQAP----LNY 495 ++ + +Y G L+ T+ +++ +I+H++Y H DIAL+K+++ Sbjct: 69 KEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQP 128 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQK-RYQ 553 + + I LPS + T+C +TG+G + L+ + L+++ ECQ+ Y Sbjct: 129 SRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYY 188 Query: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613 ++T +M+CA + D+C+GDSGGPLVC G L GI SWG GCA +++PGVYT+ Sbjct: 189 GSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTR 248 Query: 614 VAEYMDWILEKTQ 626 V+ ++ WI T+ Sbjct: 249 VSHFLPWIRSHTK 261 >5TO3-B nrPDB Length = 409 Score = 139 bits (350), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 94/253 (37%), Positives = 135/253 (53%), Gaps = 25/253 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G+++ G PWQV L + + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVML-FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 451 ILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 ++ + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ P+C Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 504 LPSKGDTSTIYTNCW---VTGWGFSKE-------KGEIQNILQKVNIPLVTNEECQKRYQ 553 LP + +++ + VTGWG KE KG+ ++LQ VN+P+V C+ + Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQ-PSVLQVVNLPIVERPVCKDSTR 178 Query: 554 DYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQP 608 +IT M CAGYK EG + DAC+GDSGGP V K N W +GI S G GC R + Sbjct: 179 -IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKY 237 Query: 609 GVYTKVAEYMDWI 621 G YT V WI Sbjct: 238 GFYTHVFRLKKWI 250 >5O32-I nrPDB Length = 244 Score = 139 bits (350), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 89/237 (37%), Positives = 126/237 (53%), Gaps = 13/237 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + G+ PWQV+++ A CGG IG W+LTAAHC ++I++ Sbjct: 1 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHR-YQIWTT 56 Query: 451 ILN-LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKP----ICLP 505 +++ + K + II H+NY +DIALI+++ N + + P C+P Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 116 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 C V+GWG K+ + + LQ + L++N C K Y + + M CAG Sbjct: 117 WSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAG 173 Query: 566 YKEGGKDACKGDSGGPLVC-KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 +G DACKGDSGGPLVC N + + G+ SWGE C + E PGVYTKVA Y DWI Sbjct: 174 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 230 >2V35-A nrPDB Length = 240 Score = 139 bits (350), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 127/237 (53%), Gaps = 10/237 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKL-TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGGT + WP Q+SLQ + ++ H CGG+LI WV+TAAHC D + +R+ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVD---RELTFRVVV 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAPLNYTEFQKPICLPSK 507 G NL+ + +++I++H + + +DIAL++L + + + LP Sbjct: 58 GEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRA 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVCAGY 566 G + C++TGWG ++ G++ LQ+ +P V C Y + MVCAG Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAG- 176 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE--GCARREQPGVYTKVAEYMDWI 621 +G + C+GDSGGPL C NG + + G+TS+ GC +P V+T+V+ Y+ WI Sbjct: 177 GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWI 233 >4NFE-A nrPDB Length = 237 Score = 138 bits (347), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 94/241 (39%), Positives = 127/241 (52%), Gaps = 22/241 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQV++ A CGG L+ QWVLTAAHC VW Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCLKKN--SQVWLGRHN 55 Query: 451 ILNLSDITKDTPFSQI-------KEIIIHQNYKVSE-GNHDIALIKLQAPLNYTEFQKPI 502 + D + P S ++ HQ+ + E +HD+ L++L P T+ K + Sbjct: 56 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 115 Query: 503 CLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRM 561 LP++ + T C+ +GWG E+ LQ V++ L++N+ C + Y + K+T+ M Sbjct: 116 GLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVTEFM 172 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDW 620 +CAG GGKD C GDSGGPLVC NG+ L GITSWG E CA E+P VYTKV Y W Sbjct: 173 LCAGLWTGGKDTCGGDSGGPLVC--NGV--LQGITSWGPEPCALPEKPAVYTKVVHYRKW 228 Query: 621 I 621 I Sbjct: 229 I 229 >2FMJ-A nrPDB Length = 222 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 82/238 (34%), Positives = 119/238 (50%), Gaps = 18/238 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGGT ++ GE+P+ V L + CGG+L VLTAAHC G G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +++L + + +++ + Q + D ALIKL P+N + T Sbjct: 54 VVDL----QSSSAVKVRSTKVLQAPGYNGTGKDWALIKLAQPINQPTLKIATTTAYNQGT 109 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 T V GWG ++E G Q L K N+P V++ C+ Y + + +CAGY GG Sbjct: 110 FT------VAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGG 163 Query: 571 KDACKGDSGGPLVCKHNG-MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 D C+GDSGGP+ K N W VGI SWGEGCAR+ + GVYT+V+ + I ++ Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAART 221 >1PQ7-A nrPDB Length = 224 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 87/238 (36%), Positives = 122/238 (51%), Gaps = 25/238 (10%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGT++S G++P+ VS+ CGGSL+ VLTAAHC G Q ++I +G Sbjct: 1 IVGGTSASAGDFPFIVSISRN---GGPWCGGSLLNANTVLTAAHCVSGY-AQSGFQIRAG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPL------NYTEFQKPICL 504 L+ T S + + +H +Y S N+D+A++KL + Y Sbjct: 57 SLSR---TSGGITSSLSSVRVHPSY--SGNNNDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNI-LQKVNIPLVTNEECQKRYQDYKITQRMVC 563 P G ++T V GWG + E G + L KV +P+V+ C+ +Y IT +M C Sbjct: 112 PVAGSSAT------VAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFC 165 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 AG GGKD+C+GDSGGP+V N L+G SWG GCAR GVY V +I Sbjct: 166 AGVSSGGKDSCQGDSGGPIVDSSN---TLIGAVSWGNGCARPNYSGVYASVGALRSFI 220 >4IGD-A nrPDB Length = 406 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 87/255 (34%), Positives = 126/255 (49%), Gaps = 22/255 (8%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQ 442 + K +I G + G PW +++ L Q CGGSL+G W++TAAHC L + Sbjct: 149 SRKLMAQIFNGRPAQKGTTPW-IAMLSHLNGQP-FCGGSLLGSSWIVTAAHCLHQSLDPE 206 Query: 443 DVWRIYSGILNLSDI------------TKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQ 490 D S +L+ SD ++ +K +H Y + +D+AL++L Sbjct: 207 DPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELL 266 Query: 491 APLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK 550 F PICLP V+GWG + L ++ IP+V + CQK Sbjct: 267 ESPVLNAFVMPICLPEGPQQEGAMV--IVSGWG-KQFLQRFPETLMEIEIPIVDHSTCQK 323 Query: 551 RYQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARRE 606 Y K +T+ M+CAG KEGGKDAC GDSGGP+V + G W LVG SWG+ C +++ Sbjct: 324 AYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKD 383 Query: 607 QPGVYTKVAEYMDWI 621 + GVY+ + DWI Sbjct: 384 RYGVYSYIHHNKDWI 398 >6BQM-A nrPDB Length = 506 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 83/251 (33%), Positives = 134/251 (53%), Gaps = 23/251 (9%) Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR- 446 S+RI+GG ++ GEWP+ V+L + + CGGS +G ++VLTAAHC D +D + Sbjct: 8 SSRIIGGEQATAGEWPYMVALTAR-NSSHVFCGGSYLGGRYVLTAAHCVDK---EDPAKG 63 Query: 447 -IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQ-APLNYTEFQKPICL 504 + G +++D+ +++I +H +Y + +DIA+++L+ PL Q I Sbjct: 64 DVLLGAFDMNDVNTAERI-HVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ--ISD 120 Query: 505 PSKGDTSTIYTNCWVTGWGFSKE----KGEIQNILQKVNIPLVTNEECQKRYQDY----- 555 S + T + V G+G KE K + IL +V +P V EC+ + D Sbjct: 121 SSDFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNN 180 Query: 556 --KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613 ++T CAG GKDAC GD+GGP+ N + +G+ SWG+GC R PGVYT Sbjct: 181 YSQLTNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTN 238 Query: 614 VAEYMDWILEK 624 ++ + DW+ ++ Sbjct: 239 LSVFNDWLDDQ 249 >5LHN-A nrPDB Length = 247 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 84/243 (34%), Positives = 132/243 (54%), Gaps = 13/243 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKL---TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 IVGG + PW ++ K + CGGSLI WV +AAHCF LP ++ + + Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAPLNY----TEFQKP 501 Y G S +++++I+H+ Y+ ++DIAL+K++ + + Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 502 ICLPSKGDTSTIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEEC-QKRYQDYKIT 558 I LP + + ++C +TG+G E + +N+ V + LV++E+C Q Y +I Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSV-VKLVSHEQCMQPHYYGSEIN 179 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYM 618 +M+CA E D+CKGDSGGPL+C G L GI SWG GCA + +PGVYT+V+ ++ Sbjct: 180 YKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFL 239 Query: 619 DWI 621 DWI Sbjct: 240 DWI 242 >1A5I-A nrPDB Length = 265 Score = 135 bits (339), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 128/246 (52%), Gaps = 15/246 (6%) Query: 393 GGTNSSWGEWPWQVSL---QVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 GG + PWQ ++ + + +R LCGG LI WVLTAAHCF L D ++ Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAP----LNYTEFQKPICLP 505 G ++ ++K+ I+H+ + N+DIAL++L++ ++ + ICLP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQKRYQDYK-ITQRMVC 563 +T C ++G+G K L++ ++ L + C ++ K +T M+C Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 564 AGYKEGGK------DACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEY 617 AG G+ DAC+GDSGGPLVC ++ L+GI SWG GC ++ PGVYTKV Y Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNY 255 Query: 618 MDWILE 623 + WI + Sbjct: 256 LGWIRD 261 >1TON-A nrPDB Length = 235 Score = 134 bits (337), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 133/247 (53%), Gaps = 36/247 (14%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQV++ +LCGG LI WV+TAAHC+ Y Sbjct: 1 IVGGYKCEKNSQPWQVAV-----INEYLCGGVLIDPSWVITAAHCYS--------NNYQV 47 Query: 451 ILNLSDITKDTPFSQ---IKEIIIHQNY-----------KVSEGNHDIALIKLQAPLNYT 496 +L +++ KD PF+Q +++ H +Y V + ++D+ L+ L P + T Sbjct: 48 LLGRNNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADIT 107 Query: 497 EFQKPICLPSKGDTSTIYTNCWVTGWGFSK-EKGEIQNILQKVNIPLVTNEECQKRYQDY 555 K I LP+K + + C +GWG + + + + LQ VNI L++NE+C + Y+D Sbjct: 108 GGVKVIDLPTK--EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKD- 164 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKV 614 +T M+CAG EGGKD C GDSGGPL+C +G+ L GITS G CA+ + P +Y K+ Sbjct: 165 NVTDVMLCAGEMEGGKDTCAGDSGGPLIC--DGV--LQGITSGGATPCAKPKTPAIYAKL 220 Query: 615 AEYMDWI 621 ++ WI Sbjct: 221 IKFTSWI 227 >2B9L-A nrPDB Length = 394 Score = 134 bits (336), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 90/261 (34%), Positives = 138/261 (52%), Gaps = 28/261 (10%) Query: 390 RIVGGTNSS-WGEWPWQVS-LQVKLTA----QRHLCGGSLIGHQWVLTAAHCFDGLPLQ- 442 +I G TN + +GE+PW V+ L+ + ++ +CGGSLI VLT AHC + Sbjct: 129 KITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNL 188 Query: 443 DVWRIYSGILNLSDITKDTPFSQ--IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500 D +I +G + + P+ + I+++IIH N+ +D+AL+ L PL + Sbjct: 189 DAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIG 248 Query: 501 PICLPSKGDTSTIY--TNCWVTGWGFSKEKG---EIQNILQKVNIPLVTNEECQKRYQD- 554 ICLP + S I+ T C+ +GWG KE G NIL+K+ +P V ++CQ ++ Sbjct: 249 TICLPQQ---SQIFDSTECFASGWG-KKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNT 304 Query: 555 -----YKITQRMVCAGYKEGGKDACKGDSGGPLVC---KHNGMWRLVGITSWGEGCARRE 606 + + Q VCAG E GKD C GD G PL C ++ + +GI +WG GC Sbjct: 305 RLGLKFVLDQTFVCAG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDEN 363 Query: 607 QPGVYTKVAEYMDWILEKTQS 627 PGVY VA + +WI ++ Q+ Sbjct: 364 VPGVYANVAHFRNWIDQEMQA 384 >1BDA-A nrPDB Length = 265 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 81/253 (32%), Positives = 132/253 (52%), Gaps = 17/253 (6%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKL---TAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVW 445 RI GG + PWQ ++ K +R LCGG LI W+L+AAHCF + P + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 446 RIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAP----LNYTEFQKP 501 I + ++ F ++++ I+H+ + ++DIAL++L++ + + Sbjct: 73 VILGRTYRVVPGEEEQKF-EVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRT 131 Query: 502 ICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQKRYQ-DYKITQ 559 +CLP +T C ++G+G + L++ ++ L + C ++ + +T Sbjct: 132 VCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTD 191 Query: 560 RMVCAGYKEGG------KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613 M+CAG G DAC+GDSGGPLVC ++G LVGI SWG GC +++ PGVYTK Sbjct: 192 NMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTK 251 Query: 614 VAEYMDWILEKTQ 626 V Y+DWI + + Sbjct: 252 VTNYLDWIRDNMR 264 >1ELT-A nrPDB Length = 236 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 119/237 (50%), Gaps = 11/237 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKL-TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGG + WPWQ+SLQ K ++ H CGGSLI WV+TAAHC D WR+ Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDS---ARTWRVVL 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAPLNYTEFQKPICLPSK 507 G NL+ + + IH + + G +DIAL++L + + LP Sbjct: 58 GEHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPS 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGY 566 C++TGWG + G + + L++ +P V + C + + MVCAG Sbjct: 118 NQILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAG- 176 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWI 621 G C GDSGGPL C+ NG + + G+TS+ GC ++P V+T+V+ Y+ W+ Sbjct: 177 -GGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWM 232 >4DJZ-B nrPDB Length = 251 Score = 133 bits (334), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 86/248 (34%), Positives = 123/248 (49%), Gaps = 22/248 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVWRIYS 449 I G + G PW +++ L Q CGGSL+G W++TAAHC L +D S Sbjct: 1 IFNGRPAQKGTTPW-IAMLSHLNGQP-FCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS 58 Query: 450 GILNLSDI------------TKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497 +L+ SD ++ +K +H Y + +D+AL++L Sbjct: 59 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK- 556 F PICLP V+GWG + L ++ IP+V + CQK Y K Sbjct: 119 FVMPICLPEGPQQEGAMVI--VSGWG-KQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKK 175 Query: 557 -ITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARREQPGVYTK 613 +T+ M+CAG KEGGKDAC GDSGGP+V + G W LVG SWG+ C ++++ GVY+ Sbjct: 176 KVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYSY 235 Query: 614 VAEYMDWI 621 + DWI Sbjct: 236 IHHNKDWI 243 >2OLG-A nrPDB Length = 278 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 85/255 (33%), Positives = 134/255 (52%), Gaps = 23/255 (9%) Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTA--QRHLCGGSLIGHQWVLTAAHCFDGLPLQDVW 445 + +I+ G ++ E+PW + K ++ ++ CGGSLI +++++TAAHC G L+ V Sbjct: 20 ADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVG 79 Query: 446 ---RIYSGILNLSD----------ITKDTPFS-QIKEIIIHQNYKVSEGN--HDIALIKL 489 ++ G N + D P I+E I H +Y + HDIALI+L Sbjct: 80 ALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRL 139 Query: 490 QAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ 549 + +T + +P+CLP + + V GWG + E G+ I QK+ +P+V E+C Sbjct: 140 NRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKLAVPVVHAEQCA 198 Query: 550 KRY--QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARRE 606 K + ++ +CAG E KD+C GDSGGPL+ + N + L G+ S+G C Sbjct: 199 KTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGATCGTEG 257 Query: 607 QPGVYTKVAEYMDWI 621 PG+YTKV +Y DWI Sbjct: 258 WPGIYTKVGKYRDWI 272 >3BEU-A nrPDB Length = 224 Score = 129 bits (325), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 80/240 (33%), Positives = 119/240 (49%), Gaps = 20/240 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGGT ++ GE+P+ V L + CGG+L VLTAAHC G G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH--DIALIKLQAPLNYTEFQKPICLPSKG 508 +++L + + +++ + Q ++ + D ALIKL P+N + Sbjct: 54 VVDL----QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQ 109 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 T T V GWG ++E G Q L K N+P V++ C+ + M+CAGY Sbjct: 110 GTFT------VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDT 163 Query: 569 GGKDACKGDSGGPLVCKHNG-MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +D C+GDSGGP+ K N W VGI SWGEGCAR+ + GVYT+V+ + I ++ Sbjct: 164 KQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAART 223 >1YM0-A nrPDB Length = 238 Score = 129 bits (325), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 81/240 (33%), Positives = 125/240 (52%), Gaps = 14/240 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + E+PWQVS++ K ++ H CGGS+I +WV+ AAHC G + + S Sbjct: 1 IVGGIEARPYEFPWQVSVRRK-SSDSHFCGGSIINDRWVVCAAHCMQG----EAPALVSL 55 Query: 451 ILNLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 ++ D + + Q + I +++NY + +D+++IK + + PIC P Sbjct: 56 VVGEHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDP 115 Query: 508 GDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 + +Y +GWG G +L+ V + + TN C Y I M+CA Sbjct: 116 AN-DYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATD 174 Query: 567 KEG--GKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 G +D+C+GDSGGPL K +G++ LVGI SWG GCA PGVY++V + WI + Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCA-SGYPGVYSRVGFHAGWITD 233 >1M9U-A nrPDB Length = 241 Score = 129 bits (324), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 81/244 (33%), Positives = 128/244 (52%), Gaps = 12/244 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GGTN+S GE+PWQ+S Q + + H CG SL+ L+A+HC DG+ ++ R+ +G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNI-RVIAG 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH--DIALIKLQAPLNYTEFQKPICLPSKG 508 + SD T T + + +H+NY ++ DIA++ L ++ + LP+ Sbjct: 60 LWQQSD-TSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY---QDYKITQRMVCAG 565 + T C ++GWG + + +ILQK +IP++T +C I +C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW----GEGCARREQPGVYTKVAEYMDWI 621 G AC GDSGGPL C G R+VG+TSW G G + P VYT+V+ Y+ WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGT-RVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 Query: 622 LEKT 625 + + Sbjct: 238 GDNS 241 >3I77-A nrPDB Length = 230 Score = 129 bits (323), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 82/241 (34%), Positives = 119/241 (49%), Gaps = 16/241 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGGT ++ GE+P+ V L + CGG+L VLTAAHC G G Sbjct: 1 VVGGTRAAQGEFPFMVRLINE--ENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH--DIALIKLQAPLNYTEFQKPICLPSKG 508 +++L + + +++ + Q ++ + D ALIKL P+N + Sbjct: 59 VVDL----QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQ 114 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 T T V GWG ++E G Q L K N+P V++ C+ + M+CAGY + Sbjct: 115 GTFT------VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPD 168 Query: 569 -GGKDACKGDSGGPLVCKHNG-MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 GG D C+GDSGGP+ K N W VGI SWG GCAR PGVYT+V+ + I + Sbjct: 169 TGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIASAAR 228 Query: 627 S 627 + Sbjct: 229 T 229 >1SGF-A nrPDB Length = 240 Score = 129 bits (323), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 83/237 (35%), Positives = 130/237 (54%), Gaps = 34/237 (14%) Query: 403 PWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTP 462 PW V++ ++ CGG L+ WVLTAAHC++ D ++++ G N +D P Sbjct: 16 PWHVAV---YRFNKYQCGGVLLDRNWVLTAAHCYN-----DKYQVWLGKNNF---LEDEP 64 Query: 463 FSQ---IKEIIIHQNYKVSEGN-----------HDIALIKLQAPLNYTEFQKPICLPSKG 508 Q + + I H ++ +S N +D+ L++L P + T+ KPI LP++ Sbjct: 65 SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTE- 123 Query: 509 DTSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + + C +GWG + K + + LQ VN+ L+ NE+C K ++ K+T M+CAG Sbjct: 124 -EPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHE-MKVTDAMLCAGEM 181 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILE 623 +GG C+ DSGGPL+C +G+ L GITSWG E C +P VYTK+ ++ WI E Sbjct: 182 DGGSYTCEHDSGGPLIC--DGI--LQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRE 234 >1EQ9-A nrPDB Length = 222 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 78/231 (33%), Positives = 130/231 (56%), Gaps = 15/231 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG ++ G++P+QVSL++ + H CG S++ + VLTAAHC DGL + +++ G Sbjct: 1 IVGGKDAPVGKYPYQVSLRL---SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 LS + +++ ++++NY +D+AL+ L P+ + + +PI L S D Sbjct: 58 TNYLS---ESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKL-STNDE 113 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C +TGWG ++ G N LQ++ + + ++C++ +++ +C K G Sbjct: 114 DLESNPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCER--DQWRVIDSHICTLTKR-G 170 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 + AC GDSGGPLV NG +GI S+G CA E P VYT+V+ ++ WI Sbjct: 171 EGACHGDSGGPLVA--NGAQ--IGIVSFGSPCALGE-PDVYTRVSSFVSWI 216 >4BXW-A nrPDB Length = 423 Score = 127 bits (318), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 82/261 (31%), Positives = 133/261 (50%), Gaps = 26/261 (9%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RIV G + GE PWQ +L + + CGG+++ +VLTAAHC + + + Sbjct: 169 RIVNGMDCKLGECPWQAALVDE--KEGVFCGGTILSPIYVLTAAHCINET---ETISVVV 223 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNY---------KVSEGNHDIALIKLQAPLNYTEFQK 500 G ++ S I + P + +I +H+ + ++ ++DIA+I+++ P+ ++E Sbjct: 224 GEIDKSRI-ETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVV 282 Query: 501 PICLPSKGDTSTIYTN---CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKI 557 P CLP+ + + V+G+G EKG L+ + +P V C + I Sbjct: 283 PACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVS-SETPI 341 Query: 558 TQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEY 617 T M CAGY +DAC+GDSGGP + + GI S GEGCAR + G YTK++++ Sbjct: 342 TPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKF 401 Query: 618 MDWI-------LEKTQSSDGK 631 + WI L T+SS G+ Sbjct: 402 IPWIKRIMRQKLPSTESSTGR 422 >1NPM-A nrPDB Length = 225 Score = 125 bits (315), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 84/224 (37%), Positives = 120/224 (53%), Gaps = 21/224 (9%) Query: 403 PWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTP 462 PWQ +L +R +CGG L+G +WVLTAAHC + + + G +L + Sbjct: 13 PWQAAL---FQGERLICGGVLVGDRWVLTAAHCK-----KQKYSVRLGDHSLQSRDQPEQ 64 Query: 463 FSQIKEIIIHQNYKVS---EGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWV 519 Q+ + I H Y S + +HDI LI+LQ N + KP+ L + + C + Sbjct: 65 EIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANL--CPKVGQKCII 122 Query: 520 TGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDS 578 +GWG + + N L + + + +C++ Y KIT+ MVCAG G D C+GDS Sbjct: 123 SGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPG-KITEGMVCAGSSNGA-DTCQGDS 180 Query: 579 GGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWI 621 GGPLVC +GM L GITSWG + C + E+PGVYTK+ Y WI Sbjct: 181 GGPLVC--DGM--LQGITSWGSDPCGKPEKPGVYTKICRYTTWI 220 >1FDP-A nrPDB Length = 235 Score = 125 bits (315), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 77/233 (33%), Positives = 116/233 (49%), Gaps = 10/233 (4%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RI+GG + P+ S+Q+ HLCGG L+ QWVL+AAHC + V ++ Sbjct: 7 RILGGREAEAHARPYMASVQLNGA---HLCGGVLVAEQWVLSAAHCLEDAADGKV-QVLL 62 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G +LS + + H + + +HD+ L++L +P+ Sbjct: 63 GAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDR 122 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKE 568 T C V GWG G + LQ V +P++ C +R + D IT+R++CA + Sbjct: 123 DVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ES 180 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 +D+CKGDSGGPLVC G+ V +TS C R++PG+YT+VA Y WI Sbjct: 181 NRRDSCKGDSGGPLVC--GGVLEGV-VTSGSRVCGNRKKPGIYTRVASYAAWI 230 >1SPJ-A nrPDB Length = 238 Score = 125 bits (315), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 86/245 (35%), Positives = 127/245 (51%), Gaps = 29/245 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQ +L T Q CGG L+ QWVLTAAHC + D ++++ G Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQ---CGGILVHRQWVLTAAHC-----ISDNYQLWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLN-YTEF 498 NL D F + E H + +S + +HD+ L++L P + T+ Sbjct: 53 RHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDA 112 Query: 499 QKPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKI 557 K + LP++ + + C +GWG E + LQ V++ ++ N+EC+K + K+ Sbjct: 113 VKVVELPTE--EPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQ-KV 169 Query: 558 TQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAE 616 T M+C G+ EGGKD C GDSGGPL+C +G+ L G+TSWG C +P V +V Sbjct: 170 TDFMLCVGHLEGGKDTCVGDSGGPLMC--DGV--LQGVTSWGYVPCGTPNKPSVAVRVLS 225 Query: 617 YMDWI 621 Y+ WI Sbjct: 226 YVKWI 230 >3QUM-P nrPDB Length = 237 Score = 125 bits (314), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 89/244 (36%), Positives = 126/244 (51%), Gaps = 28/244 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQV + + R +CGG L+ QWVLTAAHC +++ I G Sbjct: 1 IVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHC-----IRNKSVILLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYTEFQ 499 +L Q+ H Y +S + +HD+ L++L P T+ Sbjct: 53 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT 558 K + LP++ + T C+ +GWG E+ LQ V++ +++N+ C + + K+T Sbjct: 113 KVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEY 617 + M+CAG GGK C GDSGGPLVC NG+ L GITSWG E CA E+P +YTKV Y Sbjct: 170 KFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYTKVVHY 225 Query: 618 MDWI 621 WI Sbjct: 226 RKWI 229 >1AZZ-A nrPDB Length = 226 Score = 125 bits (314), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 84/242 (34%), Positives = 124/242 (51%), Gaps = 27/242 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + WP Q +L + + CGGSLI +W+LTAAHC DG DV Sbjct: 1 IVGGVEAVPNSWPHQAALFID---DMYFCGGSLISPEWILTAAHCMDGAGFVDV------ 51 Query: 451 ILNLSDITKDTPFS---QIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 +L +I +D Q + +H+NY ++DIA+I+L P+ T + LPS Sbjct: 52 VLGAHNIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPST 111 Query: 508 G-DTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 T+ T TGWG + I ++L++V++P+++N +C Y +T +C Sbjct: 112 DVGVGTVVTP---TGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG--IVTDGNICID 166 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILE 623 GGK C GDSGGPL +NG+ GITS+G GC P +T+V ++DWI Sbjct: 167 -STGGKGTCNGDSGGPL--NYNGL--TYGITSFGAAAGC-EAGYPDAFTRVTYFLDWIQT 220 Query: 624 KT 625 +T Sbjct: 221 QT 222 >2AIQ-A nrPDB Length = 231 Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/210 (37%), Positives = 112/210 (53%), Gaps = 14/210 (6%) Query: 414 AQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQ 473 A LCGG+LI +WVLTA HC G RIY G+ NL + KD KE Sbjct: 20 ANGSLCGGTLINQEWVLTARHCDRG-----NMRIYLGMHNLKVLNKDALRRFPKEKYFCL 74 Query: 474 NYKVSE-GNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEI 531 N + + DI LI+L P+ + P+ LPS + ++ + C + GWG + + Sbjct: 75 NTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPS--NPPSVGSVCRIMGWGTITSPNATL 132 Query: 532 QNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWR 591 ++ NI ++ CQ Y+ T +CAG EGGKD CKGDSGGPL+C NG ++ Sbjct: 133 PDVPHCANINILDYAVCQAAYKGLAATT--LCAGILEGGKDTCKGDSGGPLIC--NGQFQ 188 Query: 592 LVGITSWGEGCARREQPGVYTKVAEYMDWI 621 + ++ G CA+ +PG+YTKV +Y DWI Sbjct: 189 GI-LSVGGNPCAQPRKPGIYTKVFDYTDWI 217 >2PSX-A nrPDB Length = 227 Score = 124 bits (310), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 85/242 (35%), Positives = 133/242 (54%), Gaps = 20/242 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G++ PWQ +L ++ + CG L+ QW+LTAAHC + V+R+ G Sbjct: 1 IINGSDCDMHTQPWQAALLLR--PNQLYCGAVLVHPQWLLTAAHC-----RKKVFRVRLG 53 Query: 451 ILNLSDI--TKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 +LS + + F +K I H Y ++D+ LIKL + T+ +PI + S Sbjct: 54 HYSLSPVYESGQQMFQGVKSIP-HPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC 112 Query: 509 DTSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 ++ T C V+GWG +K + +LQ +NI +++ + C+ Y +I M CAG K Sbjct: 113 PSAG--TKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY-PRQIDDTMFCAGDK 169 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQ 626 G+D+C+GDSGGP+VC NG L G+ SWG+ CAR +PGVYT + ++ WI E Q Sbjct: 170 -AGRDSCQGDSGGPVVC--NG--SLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 Query: 627 SS 628 ++ Sbjct: 225 AN 226 >1Q3X-A nrPDB Length = 328 Score = 123 bits (309), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 124/247 (50%), Gaps = 20/247 (8%) Query: 387 TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVW 445 T RI GG + G++PWQV + TA G+L+ WVLTAAH ++ Sbjct: 83 TGGRIYGGQKAKPGDFPWQVLILGGTTA-----AGALLYDNWVLTAAHAVYEQKHDASAL 137 Query: 446 RIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICL 504 I G L +S+ + IH+ Y G ++DIALIKL + PICL Sbjct: 138 DIRMGTLKRLSPHYTQAWSE--AVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICL 195 Query: 505 PSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY-----KI 557 P K S + T+ +GWG + ++G + L V+IP+V +++C Y+ + Sbjct: 196 PRKEAESFMRTDDIGTASGWGLT-QRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSV 254 Query: 558 TQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGE-GCARREQPGVYTKV 614 T M+CAG + GGKD+C+GDSGG LV W + GI SWG C Q GVYTKV Sbjct: 255 TANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKV 314 Query: 615 AEYMDWI 621 Y+ WI Sbjct: 315 INYIPWI 321 >5FCR-A nrPDB Length = 234 Score = 122 bits (305), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 73/233 (31%), Positives = 116/233 (49%), Gaps = 11/233 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG ++ P+ S+QV T H+CGG+L+ QWVL+AAHC DG+ D ++ G Sbjct: 1 ILGGQEAAAHARPYMASVQVNGT---HVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +LS + ++ ++ H + D+ L KL + +P+ L + Sbjct: 58 AHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKE 117 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEG 569 T C V GWG G ++L ++ + ++ C R Y D +T M+CA + Sbjct: 118 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESN 175 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWI 621 +D C+GDSG PLVC + G+ +WG C ++PGVYT+V+ Y WI Sbjct: 176 RRDTCRGDSGSPLVCGD----AVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWI 224 >1ZJK-A nrPDB Length = 403 Score = 121 bits (304), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 88/247 (35%), Positives = 124/247 (50%), Gaps = 20/247 (8%) Query: 387 TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVW 445 T +I GG + G++PWQV + TA G+L+ WVLTAAH ++ Sbjct: 158 TGGQIYGGQKAKPGDFPWQVLILGGTTA-----AGALLYDNWVLTAAHAVYEQKHDASAL 212 Query: 446 RIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICL 504 I G L +S+ + IH+ Y G ++DIALIKL + PICL Sbjct: 213 DIRMGTLKRLSPHYTQAWSE--AVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICL 270 Query: 505 PSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY-----KI 557 P K S + T+ +GWG + ++G + L V+IP+V +++C Y+ + Sbjct: 271 PRKEAESFMRTDDIGTASGWGLT-QRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSV 329 Query: 558 TQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGE-GCARREQPGVYTKV 614 T M+CAG + GGKD+C+GDSGG LV W + GI SWG C Q GVYTKV Sbjct: 330 TANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKV 389 Query: 615 AEYMDWI 621 Y+ WI Sbjct: 390 INYIPWI 396 >1AO5-A nrPDB Length = 237 Score = 121 bits (303), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 81/244 (33%), Positives = 123/244 (50%), Gaps = 28/244 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG N PWQV++ + + H+CGG L+ WVLTAAHC+ D + ++ G Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----VDQYEVWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYTEFQ 499 L + + H + +S + + D+ L++L P + T+ Sbjct: 53 KNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT 558 KPI LP+K + C +GWG + + + + LQ V I L+ NE C K Y K+T Sbjct: 113 KPIALPTKEPKPG--SKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEY 617 M+CAG GGKD C+ DSGGPL+C +G+ L G TS+G C + P +YT + ++ Sbjct: 170 DVMLCAGEMGGGKDTCRDDSGGPLIC--DGI--LQGTTSYGPVPCGKPGVPAIYTNLIKF 225 Query: 618 MDWI 621 WI Sbjct: 226 NSWI 229 >3BSQ-A nrPDB Length = 227 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 80/235 (34%), Positives = 121/235 (51%), Gaps = 23/235 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G + G PWQV+L L+ + CGG L+ +WVLTAAHC + + ++ G Sbjct: 1 IIDGAPCARGSHPWQVAL---LSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLG 52 Query: 451 ILNLSDITKDTPFSQIK--EIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 SD D +IK + H Y +D+ L+KL + + K + LPS+ Sbjct: 53 ----SDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC 108 Query: 509 DTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + T C V+GWG + + L V++ L++ ++C K Y+D + M+CAG Sbjct: 109 EPPG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIP 165 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 621 + K+AC GDSGGPLVC+ L G+ SWG C + PGVYT+V ++ WI Sbjct: 166 DSKKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 216 >2XXL-A nrPDB Length = 408 Score = 120 bits (301), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 92/289 (31%), Positives = 138/289 (47%), Gaps = 42/289 (14%) Query: 379 DNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFD 437 +N C S R+ G PW L+ + + R LCGG++I +++LTAAHC Sbjct: 107 ENFDCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVH 166 Query: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQ--------------IKEIIIHQNYKVSEGNHD 483 GL D++ I G +S T++ Q I++ +IH+ Y HD Sbjct: 167 GLQ-NDLYEIRLGEHRIS--TEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHD 223 Query: 484 IALIKLQAPLNYTEFQKPICLP------SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQK 537 IAL+KL + + + KPICLP K + + Y +VTGWG + E G ++L + Sbjct: 224 IALLKLNRSVPFQKHIKPICLPITDELKEKAEQISTY---FVTGWG-TTENGSSSDVLLQ 279 Query: 538 VNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG--KDACKGDSGGPLVCKHNGMWRLV-- 593 N+PL C + Y+ + +C G GG +D+CKGDSGGPL + Sbjct: 280 ANVPLQPRSACSQAYR-RAVPLSQLCVG---GGDLQDSCKGDSGGPLQAPAQYLGEYAPK 335 Query: 594 ----GITSWG-EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSP 637 GI S G C + PG+YT V EY+ WI + T +S+G + + P Sbjct: 336 MVEFGIVSQGVVTCGQISLPGLYTNVGEYVQWITD-TMASNGLLESRGP 383 >1SI5-H nrPDB Length = 240 Score = 120 bits (301), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 75/221 (33%), Positives = 118/221 (53%), Gaps = 14/221 (6%) Query: 404 WQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPF 463 W VSL+ + +H+CGGSLI WVLTA CF L+D Y L + D+ Sbjct: 13 WMVSLRYR---NKHICGGSLIKESWVLTARQCFPSRDLKD----YEAWLGIHDVHGRGDE 65 Query: 464 SQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG 523 + + + Q EG+ D+ L+KL P +F I LP+ G T T+C V GWG Sbjct: 66 KCKQVLNVSQLVYGPEGS-DLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWG 124 Query: 524 FSKEKGEI--QNILQKVNIPLVTNEECQKRYQ-DYKITQRMVCAGYKEGGKDACKGDSGG 580 ++ G I +L+ ++ ++ NE+C + ++ + + +CAG ++ G C+GD GG Sbjct: 125 YT---GLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGG 181 Query: 581 PLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 PLVC+ + M ++G+ G GCA +PG++ +VA Y WI Sbjct: 182 PLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 222 >5MS3-A nrPDB Length = 228 Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 85/238 (35%), Positives = 121/238 (50%), Gaps = 25/238 (10%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG PWQ +L Q+ LCGG L+G WVLTAAHC + + + G Sbjct: 1 VLGGHECQPHSQPWQAAL---FQGQQLLCGGVLVGGNWVLTAAHCK-----KPKYTVRLG 52 Query: 451 ILNLSDITKDTPFSQIKEI--IIHQNYK---VSEGNHDIALIKLQAPLNYTEFQKPICLP 505 +L + KD P +I + I H Y V + NHD+ L++L+ + KPI L Sbjct: 53 DHSLQN--KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLA 110 Query: 506 SKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 564 + C V+GWG + + + L + + ++C+ Y +IT MVCA Sbjct: 111 DH--CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPG-QITDGMVCA 167 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWI 621 G +G D C+GDSGGPLVC L GITSWG + C R ++PGVYT + Y+DWI Sbjct: 168 GSSKGA-DTCQGDSGGPLVCDG----ALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 220 >4FXG-H nrPDB Length = 242 Score = 118 bits (295), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 86/250 (34%), Positives = 126/250 (50%), Gaps = 34/250 (13%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-----DGLPLQDVW 445 I GG + G++PWQV + TA G+L+ WVLTAAH D L Sbjct: 1 IYGGQKAKPGDFPWQVLILGGTTA-----AGALLYDNWVLTAAHAVYEQKHDASALD--- 52 Query: 446 RIYSGILNLSDITKDTP-FSQI--KEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKP 501 + + + + +P ++Q + + IH+ Y G ++DIALIKL + P Sbjct: 53 ------IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 106 Query: 502 ICLPSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQD----- 554 ICLP K S + T+ +GWG + ++G + L V+IP+V +++C Y+ Sbjct: 107 ICLPRKEAESFMRTDDIGTASGWGLT-QRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPR 165 Query: 555 YKITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGE-GCARREQPGVY 611 +T M+CAG + GGKD+C+GD+GG LV W + GI SWG C Q GVY Sbjct: 166 GSVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVY 225 Query: 612 TKVAEYMDWI 621 TKV Y+ WI Sbjct: 226 TKVINYIPWI 235 >2ZKS-A nrPDB Length = 240 Score = 117 bits (294), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 80/243 (32%), Positives = 118/243 (48%), Gaps = 17/243 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG P+ SLQ + HLCGG L+ +WVLTAAHC R+ Sbjct: 1 IIGGREVIPHSRPYMASLQRNGS---HLCGGVLVHPKWVLTAAHCL-------AQRMAQL 50 Query: 451 ILNLSDITKDTP--FSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 L L T D+P IK I H YK V +D+AL++L + + +P+ LPSK Sbjct: 51 RLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSK 110 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGY 566 T C + GWG + + G + +L+++++ ++ C R+ + ++ MVC Sbjct: 111 RQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAA 170 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWILEKT 625 + CKGDSGGPLVC + L G+ S+ C +P V T VA Y+ WI + T Sbjct: 171 DSKDQAPCKGDSGGPLVCGKGRV--LAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVT 228 Query: 626 QSS 628 S Sbjct: 229 GRS 231 >4E7N-A nrPDB Length = 238 Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 83/238 (34%), Positives = 128/238 (53%), Gaps = 21/238 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + E + V+L ++ CGG+LI +WVLTAAHC + +RI G Sbjct: 1 IIGGDECNINEHRFLVALYTS-RSRTLFCGGTLINQEWVLTAAHCD-----RKNFRIKLG 54 Query: 451 ILNLSDITKDTPFSQIKE---IIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 + + +D KE + +NY + + DI LI+L +P+ ++ Sbjct: 55 MHSKKVPNEDEQTRVPKEKFFCLSSKNYTLWD--KDIMLIRLDSPVKNSKHIA--PFSLP 110 Query: 508 GDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKI--TQRMVCA 564 ++ + C + GWG S +G ++ VNI L+ E C+ Y ++++ T R +CA Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWI 621 G EGGKD CKGDSGGPL+C NG ++ GI SWG+ CA+ +P YTKV +++DWI Sbjct: 171 GILEGGKDTCKGDSGGPLIC--NGQFQ--GIASWGDDPCAQPHKPAAYTKVFDHLDWI 224 >4GSO-A nrPDB Length = 232 Score = 116 bits (291), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 85/235 (36%), Positives = 123/235 (52%), Gaps = 21/235 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG E P+ L + + CG +LI +WV+TAAHC D Q ++S Sbjct: 1 VLGGDECDINEHPFLAFLY----SHGYFCGLTLINQEWVVTAAHC-DSTNFQMQLGVHSK 55 Query: 451 -ILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKG 508 +LN + T++ KE I N +SE + DI LIKL P++ ++ P+ LPS Sbjct: 56 KVLNEDEQTRNP-----KEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPS-- 108 Query: 509 DTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + ++ + C + GWG E ++ NI LV E CQ Y + +CAG Sbjct: 109 NPPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLP-AKTTLCAGVL 167 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWI 621 EGGKD C GDSGGPL+C NG ++ GI S+G C + +PG+YT V +Y DWI Sbjct: 168 EGGKDTCVGDSGGPLIC--NGQFQ--GIVSYGAHSCGQGPKPGIYTNVFDYTDWI 218 >1GPZ-A nrPDB Length = 399 Score = 115 bits (289), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 82/266 (30%), Positives = 132/266 (49%), Gaps = 33/266 (12%) Query: 382 VCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPL 441 V + +I+GG + G +PWQV + GG+L+G +W+LTAAH P Sbjct: 149 VNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTL--YPK 201 Query: 442 QDVWR------IYSGILNLSDITK--DTPFSQIKEIIIHQNYKVSEGNH---DIALIKLQ 490 + + ++ G N+ ++ K + P I+ + +H +Y+ E + DIAL++L+ Sbjct: 202 EHEAQSNASLDVFLGHTNVEELMKLGNHP---IRRVSVHPDYRQDESYNFEGDIALLELE 258 Query: 491 APLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ- 549 + PICLP + +V+G+G +EK I + L+ V +P+ + C+ Sbjct: 259 NSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACEN 316 Query: 550 ----KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGCA 603 K D +Q M CAG+ +DAC+GDSGG + + W GI SWG GC+ Sbjct: 317 WLRGKNRMDV-FSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCS 375 Query: 604 RREQPGVYTKVAEYMDWILEKTQSSD 629 R G YTKV Y+DWI ++ + D Sbjct: 376 RGY--GFYTKVLNYVDWIKKEMEEED 399 >3S9B-A nrPDB Length = 234 Score = 115 bits (287), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 79/233 (33%), Positives = 120/233 (51%), Gaps = 15/233 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG + E P+ V+L ++ H C G+LI +WVLTAAHC + RI G Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHCD-----RRNIRIKLG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + + +D + N K G + DI LI+L+ P+ Y+ P+ LPS+ Sbjct: 55 MHSKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSR-- 112 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + + + C + GWG ++ NI +V ++ C+ Y R +CAG +G Sbjct: 113 SRGVGSRCRIMGWG-KISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKG 171 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWI 621 G+D C GDSGGPL+C NG + GI + G E C + +P VYTKV +Y +WI Sbjct: 172 GRDTCHGDSGGPLIC--NG--EMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWI 220 >1FON-A nrPDB Length = 240 Score = 114 bits (286), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 83/240 (34%), Positives = 119/240 (49%), Gaps = 22/240 (9%) Query: 402 WPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKD 460 W WQVSLQ K A H CGGSLI WV+TA HC R Y +L D + Sbjct: 10 WSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS------RTYQVVLGEYDRSVL 63 Query: 461 TPFSQI-----KEIIIHQNYK---VSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTST 512 Q+ ++ +H + V+ GN DIAL+KL + + LP GD Sbjct: 64 EGSEQVIPINAGDLFVHPLWNSNCVACGN-DIALVKLSRSAQLGDKVQLANLPPAGDILP 122 Query: 513 IYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVCAGYKEGGK 571 C+++GWG G + + LQ+ +P V E C Q + + + MVCAG + Sbjct: 123 NEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT--R 180 Query: 572 DACKGDSGGPLVC-KHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSS 628 C GDSGGPL C +G W++ G+TS+ GC ++P V+T+V+ ++DWI E S+ Sbjct: 181 SGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIASN 240 >2QY0-B nrPDB Length = 242 Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 81/255 (31%), Positives = 127/255 (49%), Gaps = 29/255 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR---- 446 I+GG + G +PWQV T GG+L+G +W+LTAAH P + + Sbjct: 1 IIGGQKAKMGNFPWQV-----FTNIHGRGGGALLGDRWILTAAHTL--YPKEHEAQSNAS 53 Query: 447 --IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH---DIALIKLQAPLNYTEFQKP 501 ++ G N+ ++ K I+ + +H +Y+ E + DIAL++L+ + P Sbjct: 54 LDVFLGHTNVEELMK-LGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLP 112 Query: 502 ICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-----KRYQDYK 556 ICLP + +V+G+G +EK I + L+ V +P+ + C+ K D Sbjct: 113 ICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDV- 169 Query: 557 ITQRMVCAGYKEGGKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARREQPGVYTKV 614 +Q M CAG+ +DAC+GDSGG + + W GI SWG GC+R G YTKV Sbjct: 170 FSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGY--GFYTKV 227 Query: 615 AEYMDWILEKTQSSD 629 Y+DWI ++ + D Sbjct: 228 LNYVDWIKKEMEEED 242 >5ZFH-A nrPDB Length = 224 Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 79/241 (32%), Positives = 119/241 (49%), Gaps = 23/241 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G G PWQV+L L + CGG L+ WVLTAAHC G +++ G Sbjct: 1 IIDGYKCKEGSHPWQVAL---LKGNQLHCGGVLVDKYWVLTAAHCKMGQ-----YQVQLG 52 Query: 451 ILNLSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 SD D +IK H Y +DI L++L P+ + + + LP Sbjct: 53 ----SDKIGDQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHC 108 Query: 509 DTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + T+C V+GWG + + L ++ L+++ EC+K Y+D + + M+CAG Sbjct: 109 EPPG--TSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDL-LGKTMLCAGIP 165 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQ 626 + + C GDSGGPLVC L G+ SWG C + PGVYT+V +Y W++E + Sbjct: 166 DSKTNTCNGDSGGPLVCNDT----LQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 Query: 627 S 627 + Sbjct: 222 T 222 >1MD7-A nrPDB Length = 328 Score = 114 bits (284), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 131/263 (49%), Gaps = 33/263 (12%) Query: 382 VCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPL 441 V + RI+GG + G +PWQV + GG+L+G +W+LTAAH P Sbjct: 81 VNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTL--YPK 133 Query: 442 QDVWR------IYSGILNLSDITK--DTPFSQIKEIIIHQNYKVSEGNH---DIALIKLQ 490 + + ++ G N+ ++ K + P I+ + +H +Y+ E + DIAL++L+ Sbjct: 134 EHEAQSNASLDVFLGHTNVEELMKLGNHP---IRRVSVHPDYRQDESYNFEGDIALLELE 190 Query: 491 APLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ- 549 + PICLP + +V+G+G +EK I + L+ V +P+ + C+ Sbjct: 191 NSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACEN 248 Query: 550 ----KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGCA 603 K D +Q M CAG+ +DAC+GD+GG + + W GI SWG GC+ Sbjct: 249 WLRGKNRMDV-FSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCS 307 Query: 604 RREQPGVYTKVAEYMDWILEKTQ 626 R G YTKV Y+DWI ++ + Sbjct: 308 RGY--GFYTKVLNYVDWIKKEME 328 >4LK4-A nrPDB Length = 357 Score = 112 bits (280), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 90/253 (35%), Positives = 130/253 (51%), Gaps = 22/253 (8%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTA---QRHLCGGSLIGHQWVLTAAHCFDGLP 440 T S+RI+ G+N++ EWP V+L VK A Q CGGS +G ++VLTAAHCFD Sbjct: 4 TADISSRIINGSNANSAEWPSIVAL-VKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRS 62 Query: 441 LQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500 V + G +L++ ++ + ++I H +Y S +DIA+++L T Sbjct: 63 AASV-DVIIGAYDLNNSSQGERIAA-QKIYRHLSYSPSNLLNDIAIVELAQ----TSSLP 116 Query: 501 PICL--PSKGDTSTIYTNCWVTGWGFSKEKGEIQ--NILQKVNIPLVTNEECQKRYQ--- 553 I L P+ + T V GWG + + Q ILQ+V++ LV+ CQ Q Sbjct: 117 AITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGI 176 Query: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYT 612 CA KD+C+GD+GGP+V K G +L GI SWG E CA+ GVYT Sbjct: 177 SSDPNSTNFCAARLT--KDSCQGDAGGPIVVK-TGREQL-GIVSWGDEQCAKTGTYGVYT 232 Query: 613 KVAEYMDWILEKT 625 V+ + DWI + T Sbjct: 233 NVSYFRDWITKHT 245 >1BQY-A nrPDB Length = 234 Score = 111 bits (278), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 80/218 (36%), Positives = 121/218 (55%), Gaps = 14/218 (6%) Query: 407 SLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG-ILNLSDITKDTPFSQ 465 SL V + LCGG+LI WV+TAAHC D Q ++ ++S ILN + T+D Sbjct: 14 SLVVLFNSNGFLCGGTLINQDWVVTAAHC-DSNNFQLLFGVHSKKILNEDEQTRDPK--- 69 Query: 466 IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFS 525 ++ K E + DI LIKL + ++ +E P+ LPS ++ + C + GWG + Sbjct: 70 -EKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSS--PPSVGSVCRIMGWGKT 126 Query: 526 KEKGEI-QNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVC 584 EI ++ NI ++ + C+ Y ++ +CAG +GG+D C DSGGPL+C Sbjct: 127 IPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDTCHFDSGGPLIC 186 Query: 585 KHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWI 621 NG+++ GI SW G C + +PGVYTKV +Y+DWI Sbjct: 187 --NGIFQ--GIVSWGGHPCGQPGEPGVYTKVFDYLDWI 220 >1GVZ-A nrPDB Length = 237 Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/252 (32%), Positives = 128/252 (50%), Gaps = 30/252 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG PWQV++ Q H CGG L+ QWVLTAAHC + D ++I+ Sbjct: 1 IIGGWECEKHSKPWQVAV----YHQGHFQCGGVLVHPQWVLTAAHC-----MSDDYQIWL 51 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYTEF 498 G NLS F Q+ + + + +S + +HD+ L++L P T+ Sbjct: 52 GRHNLSKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDA 111 Query: 499 QKPICLPSKGDTSTIYTNCWVTGWGF-SKEKGEIQNILQKVNIPLVTNEECQKRYQDYKI 557 K + LP++ + + C+ +GWG S LQ V + L +NE+C + Y + K+ Sbjct: 112 VKILDLPTQ--EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPE-KM 168 Query: 558 TQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAE 616 T+ ++CA +++ C GDSGG L+C +G+++ GITSWG CA V+TKV Sbjct: 169 TEFVLCATHRDDSGSICLGDSGGALIC--DGVFQ--GITSWGYSECADFNDNFVFTKVMP 224 Query: 617 YMDWILEKTQSS 628 + WI E + + Sbjct: 225 HKKWIKETIEKN 236 >1MZD-A nrPDB Length = 240 Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 82/237 (34%), Positives = 117/237 (49%), Gaps = 13/237 (5%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG S P+ S+Q H+CGG LI QWVLTAAHC + Sbjct: 2 EIIGGKEVSPHSRPFMASIQY---GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 58 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G +LS +IK+ I ++DI L+KLQ + K + + SK Sbjct: 59 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTS 118 Query: 510 TSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEEC--QKRYQ-DYKITQRMVCAG 565 + T C VTGWG + + L++V + +++ + C Q Y D IT+ MVCAG Sbjct: 119 LRS-GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 177 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA-EYMDWI 621 +G KD+CKGD+GGPL+CK G++ I S G C +PG+YT + +Y WI Sbjct: 178 DAKGQKDSCKGDAGGPLICK--GVFH--AIVSGGHECGVATKPGIYTLLTKKYQTWI 230 >1ORF-A nrPDB Length = 234 Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 121/241 (50%), Gaps = 23/241 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ V L + ++ +C G+LI WVLTAAHC ++ + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHC-------NLNKRSQV 50 Query: 451 ILNLSDITKDTPFSQI---KEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 IL IT++ P QI K+ + Y + D+ L++L ++ + LP K Sbjct: 51 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKK 110 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQ---DYKITQRMVCA 564 GD T C V GWG + + L++V I ++ + C R + I MVCA Sbjct: 111 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCA 170 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVA-EYMDWI 621 G GG+D+C GDSG PL+C+ G++R G+TS+G C PGVY ++ ++++WI Sbjct: 171 GSLRGGRDSCNGDSGSPLLCE--GVFR--GVTSFGLENKCGDPRGPGVYILLSKKHLNWI 226 Query: 622 L 622 + Sbjct: 227 I 227 >2PKA-B nrPDB Length = 152 Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 63/146 (43%), Positives = 89/146 (60%), Gaps = 13/146 (8%) Query: 481 NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKG----EIQNILQ 536 +HD+ L++LQ+P T+ K + LP++ + + C +GWG S E G E + +Q Sbjct: 7 SHDLMLLRLQSPAKITDAVKVLELPTQ--EPELGSTCEASGWG-SIEPGPDDFEFPDEIQ 63 Query: 537 KVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGIT 596 V + L+ N C + D K+T+ M+CAGY GGKD C GDSGGPL+C NGMW+ GIT Sbjct: 64 CVQLTLLQNTFCADAHPD-KVTESMLCAGYLPGGKDTCMGDSGGPLIC--NGMWQ--GIT 118 Query: 597 SWGE-GCARREQPGVYTKVAEYMDWI 621 SWG C +P +YTK+ Y+DWI Sbjct: 119 SWGHTPCGSANKPSIYTKLIFYLDWI 144 >1EUF-A nrPDB Length = 227 Score = 108 bits (271), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 72/231 (31%), Positives = 112/231 (48%), Gaps = 12/231 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ L K + + H+CGG L+ +VLTAAHC L + G Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHC-----LGSSINVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + ++ I H +Y +DI L+KL + T+ PI LP Sbjct: 56 AHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAE 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C V GWG + LQ+V++ + + E+C R+++Y I +CAG Sbjct: 116 VKPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNY-IPFTQICAGDPSKR 174 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 K++ GDSGGPLVC NG+ + GI S+G P VYT+++ ++ WI Sbjct: 175 KNSFSGDSGGPLVC--NGVAQ--GIVSYGRNDG--TTPDVYTRISSFLSWI 219 >2HLC-A nrPDB Length = 230 Score = 107 bits (268), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 121/242 (50%), Gaps = 23/242 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+ G + G +P+Q L + L QR + CGGSLI ++W+LTAAHC V S Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHC--------VHDAVS 52 Query: 450 GILNLSDITKDTPFSQI--KEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 ++ L + + + + II H + +D+ALIK+ + YT+ +PI LPS Sbjct: 53 VVVYLGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSG 111 Query: 508 GDTSTIYTNCW--VTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 + + + N W V+GWG S ILQ ++ N+ C + Y I + +C G Sbjct: 112 EELNNKFENIWATVSGWGQSNTD---TVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-G 167 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILE 623 GK C GDSGGP V + L+G+ S+ G GC +P +++V YMDWI + Sbjct: 168 DTSDGKSPCFGDSGGPFVLSDKNL--LIGVVSFVSGAGC-ESGKPVGFSRVTSYMDWIQQ 224 Query: 624 KT 625 T Sbjct: 225 NT 226 >1FUJ-A nrPDB Length = 221 Score = 106 bits (264), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 111/235 (47%), Gaps = 23/235 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + P+ SLQ++ H CGG+LI +VLTAAHC +P R+ + Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QRLVNV 56 Query: 451 ILNLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 +L ++ P Q + ++ ++ NY +DI LI+L +P N + + LP + Sbjct: 57 VLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQ 115 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 T C GWG +LQ++N+ +VT + +C Sbjct: 116 DQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVP 165 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 621 C GDSGGPL+C +G+ + GI S+ GCA R P +T+VA Y+DWI Sbjct: 166 RRKAGICFGDSGGPLIC--DGI--IQGIDSFVIWGCATRLFPDFFTRVALYVDWI 216 >3RP2-A nrPDB Length = 224 Score = 106 bits (264), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 110/236 (46%), Gaps = 22/236 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG S P+ L V R +CGG LI Q+VLTAAHC R + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKG--------REIT 52 Query: 450 GILNLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506 IL D+ K Q +++ IIH++Y HDI L+KL+ + T + LPS Sbjct: 53 VILGAHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPS 112 Query: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVCAG 565 D CW GWG + + L++V + ++ + C RY +YK VC G Sbjct: 113 PSDFIHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKF---QVCVG 169 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 + A GDSGGPL+C GI S+G A+ P ++T+V+ Y+ WI Sbjct: 170 SPTTLRAAFMGDSGGPLLCAGVAH----GIVSYGHPDAK--PPAIFTRVSTYVPWI 219 >2BDH-A nrPDB Length = 223 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 83/241 (34%), Positives = 126/241 (52%), Gaps = 22/241 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G + S PWQ +L ++ C G L+ QWVL+AAHCF Q+ + I G Sbjct: 1 IINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLG 52 Query: 451 ILNLSDITKDTPFSQIKEI---IIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 + +L P SQ+ E + H Y +D+ LIKL ++ ++ + I + S+ Sbjct: 53 LHSLE--ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ 110 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 T+ +C V+GWG G + +LQ VN+ +V+ E C K Y D M CAG Sbjct: 111 CPTAG--NSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGG 166 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWILEKTQ 626 + KD+C GDSGGPL+C NG L G+ S+G+ C + PGVYT + ++ +WI + Q Sbjct: 167 QDQKDSCNGDSGGPLIC--NGY--LQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 Query: 627 S 627 + Sbjct: 223 A 223 >1OP0-A nrPDB Length = 234 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 82/235 (34%), Positives = 122/235 (51%), Gaps = 19/235 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG E + V+ CGG+LI +WV+TAAHC D Q ++S Sbjct: 1 VIGGNECDINEHRFLVAF---FNTTGFFCGGTLINPEWVVTAAHC-DSTDFQMQLGVHSK 56 Query: 451 -ILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKG 508 +LN + T++ KE I N +E + DI LIKL P++ ++ P+ LPS Sbjct: 57 KVLNEDEQTRNP-----KEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSS- 110 Query: 509 DTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 ++ + C + GWG + K ++ NI L+ + CQ Y + R +CAG Sbjct: 111 -PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIV 169 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWI 621 +GGKD C GDSGGPL+C NG ++ GI S+G C + +PG+YT V +Y DWI Sbjct: 170 QGGKDTCGGDSGGPLIC--NGQFQ--GIVSYGAHPCGQGPKPGIYTNVFDYTDWI 220 >5XRF-A nrPDB Length = 242 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 75/208 (36%), Positives = 107/208 (51%), Gaps = 18/208 (8%) Query: 419 CGGSLIGHQWVLTAAHCFD-GLPLQDVWRIYSGILNLS-DITKDTPFSQIKEIIIHQNYK 476 C G+LI +WVL AAHC+ GL IY G+ N S + I+E + K Sbjct: 34 CAGTLIHEEWVLAAAHCYKRGL------NIYLGMHNQSIQFDDEQRRYAIEEHYYRCDEK 87 Query: 477 VSEGNHDIALIKLQAPL-NYTEFQKPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNI 534 +++ D+ L+KL P+ N T S ++ C V GWG S K + ++ Sbjct: 88 LTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSIGSV---CRVMGWGIMSSTKDILPDV 144 Query: 535 LQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVG 594 NI L+ EC Y D T R++CAG EGG D C DSGGPL+C +G ++ G Sbjct: 145 PHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGGIDTCNQDSGGPLIC--DGQFQ--G 200 Query: 595 ITSWGE-GCARREQPGVYTKVAEYMDWI 621 I +G+ CA+ +PG+YT+V+ Y DWI Sbjct: 201 IVFFGKYPCAQPNKPGLYTRVSNYNDWI 228 >1ELV-A nrPDB Length = 333 Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 122/259 (47%), Gaps = 33/259 (12%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RI+GG+++ +PWQV GG+LI WVLTAAH +G + + S Sbjct: 82 RIIGGSDADIKNFPWQVFFD------NPWAGGALINEYWVLTAAHVVEGN-REPTMYVGS 134 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYK---VSEG----NHDIALIKLQAPLNYTEFQKPI 502 + S + K + + + IH +K V EG ++DIAL++L+ P+ PI Sbjct: 135 TSVQTSRLAKSKMLTP-EHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 193 Query: 503 CLPSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK--------RY 552 CLP + ++GWG + EK + L+ +P+ +C++ Sbjct: 194 CLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 252 Query: 553 QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG---MWRLVGITSWGEGCARREQPG 609 + Y T M+CAG E G D+CKGDSGG + + G+ SWG C G Sbjct: 253 EAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY---G 308 Query: 610 VYTKVAEYMDWILEKTQSS 628 +YT+V Y+DWI++ Q + Sbjct: 309 LYTRVKNYVDWIMKTMQEN 327 >5UBM-A nrPDB Length = 252 Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 122/259 (47%), Gaps = 33/259 (12%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RI+GG+++ +PWQV GG+LI WVLTAAH +G + + S Sbjct: 1 RIIGGSDADIKNFPWQVFFD------NPWAGGALINEYWVLTAAHVVEG-NREPTMYVGS 53 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYK---VSEG----NHDIALIKLQAPLNYTEFQKPI 502 + S + K + + + IH +K V EG ++DIAL++L+ P+ PI Sbjct: 54 TSVQTSRLAKSKMLTP-EHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 112 Query: 503 CLPSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK--------RY 552 CLP + ++GWG + EK + L+ +P+ +C++ Sbjct: 113 CLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 553 QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG---MWRLVGITSWGEGCARREQPG 609 + Y T M+CAG E G D+CKGDSGG + + G+ SWG C G Sbjct: 172 EAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY---G 227 Query: 610 VYTKVAEYMDWILEKTQSS 628 +YT+V Y+DWI++ Q + Sbjct: 228 LYTRVKNYVDWIMKTMQEN 246 >1FI8-A nrPDB Length = 228 Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 71/239 (29%), Positives = 116/239 (48%), Gaps = 12/239 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG + P+ LQ+ + CGG LI +VLTAAHC G +Q + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-SGSKIQ----VTL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N+ + K + +II H Y ++DI L+KL++ + KP+ LP + Sbjct: 56 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 115 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 C+V GWG G+ + LQ+V + + +++C+ ++Y +CAG + Sbjct: 116 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 175 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 + + +GDSGGPLVCK GI S+G+ P +TKV+ ++ WI + + S Sbjct: 176 KRASFRGDSGGPLVCKKVA----AGIVSYGQNDG--STPRAFTKVSTFLSWIKKTMKKS 228 >4J1Y-A nrPDB Length = 397 Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 77/260 (29%), Positives = 121/260 (46%), Gaps = 33/260 (12%) Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448 R +GG+++ +PWQV GG+LI WVLTAAH +G + + Sbjct: 145 ARAIGGSDADIKNFPWQVFFD------NPWAGGALINEYWVLTAAHVVEGN-REPTMYVG 197 Query: 449 SGILNLSDITKDTPFSQIKEIIIHQNYK---VSEG----NHDIALIKLQAPLNYTEFQKP 501 S + S + K + + + IH +K V EG ++DIAL++L+ P+ P Sbjct: 198 STSVQTSRLAKSKMLTP-EHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSP 256 Query: 502 ICLPSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK--------R 551 ICLP + ++GWG + EK + L+ +P+ +C++ Sbjct: 257 ICLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTAD 315 Query: 552 YQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG---MWRLVGITSWGEGCARREQP 608 + Y T M+CAG E G D+CKGDSGG + + G+ SWG C Sbjct: 316 AEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY--- 371 Query: 609 GVYTKVAEYMDWILEKTQSS 628 G+YT+V Y+DWI++ Q + Sbjct: 372 GLYTRVKNYVDWIMKTMQEN 391 >3S69-A nrPDB Length = 234 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 82/235 (34%), Positives = 118/235 (50%), Gaps = 19/235 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG + E SL + C G+LI +WVLTAAHC D Q ++S Sbjct: 1 VIGGDECNINE---HRSLVAFFNSTGFFCSGTLINEEWVLTAAHC-DNTNFQMKLGVHSK 56 Query: 451 -ILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKG 508 +LN + T++ KE I N K E + DI LIKL + ++ +E + L Sbjct: 57 KVLNEDEQTRNP-----KEKFICPNKKNDEVLDKDIMLIKLDSRVSNSE--HIVPLSLPS 109 Query: 509 DTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 ++ + C + GWG + K ++ I L+ + CQ Y + R +CAG Sbjct: 110 SPPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGIL 169 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWI 621 EGGKD C GDSGGPL+C NG ++ GI S+G C + +PGVYTKV +Y WI Sbjct: 170 EGGKDTCGGDSGGPLIC--NGQFQ--GIVSFGAHPCGQGLKPGVYTKVFDYNHWI 220 >2ASU-B nrPDB Length = 234 Score = 99.8 bits (247), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 70/233 (30%), Positives = 115/233 (49%), Gaps = 14/233 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDG--LPLQDVWRIY 448 +VGG G PW VSL+ + +H CGGSL+ QW+LTA CF +PL + ++ Sbjct: 1 VVGGHP---GNSPWTVSLRNR--QGQHFCGGSLVKEQWILTARQCFSSCHMPLTG-YEVW 54 Query: 449 SGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G L + P ++ + + + G+ + L+KL+ + + ICLP + Sbjct: 55 LGTL-FQNPQHGEP--SLQRVPVAKMVCGPSGS-QLVLLKLERSVTLNQRVALICLPPEW 110 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 T C + GWG +K G +L + +++N+EC +++ ++ + +C Sbjct: 111 YVVPPGTKCEIAGWGETKGTGN-DTVLNVALLNVISNQECNIKHRG-RVRESEMCTEGLL 168 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 AC+GD GGPL C + W L GI CAR P V+T+V+ ++DWI Sbjct: 169 APVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWI 221 >3G01-A nrPDB Length = 227 Score = 99.8 bits (247), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 16/234 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG S P+ + +K+ ++ CGG L+ ++VLTAAHC G + + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC-KGRSMT----VTL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N+ + + + I H +Y + ++DI L+KL T +P+ LP + Sbjct: 56 GAHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNA 115 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 C+V GWG GE L +V + + ++ C+ ++Q +C G + Sbjct: 116 HVKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKI 175 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWI 621 + +GDSGGPLVCK GI S+G +G A P V+T+V ++ WI Sbjct: 176 KGASFRGDSGGPLVCKRAA----AGIVSYGQTDGSA----PQVFTRVLSFVSWI 221 >5LPF-A nrPDB Length = 234 Score = 99.4 bits (246), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 116/246 (47%), Gaps = 29/246 (11%) Query: 394 GTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVW-RIYSGIL 452 G+ + G PWQVSL L+ C G L+ WVLTAAHC + + +W R+ L Sbjct: 7 GSPCARGSQPWQVSLFNGLSFH---CAGVLVDQSWVLTAAHCGN----KPLWARVGDDHL 59 Query: 453 NLSDITKDTPFSQIKEIIIHQNYKVSEG--------NHDIALIKLQAPLNYTEFQKPICL 504 L + + ++H Y G HD+ L+KL P+ + + L Sbjct: 60 LL---LQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQL 116 Query: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNI-LQKVNIPLVTNEECQKRYQDYKITQRMVC 563 P + + C V GWG + + N L +I +++ +EC+ Y +T M+C Sbjct: 117 PYR--CAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGV-VTNNMIC 173 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWIL 622 AG G+D C+ DSGGPLVC L GI SWG C + P VYT++ +YM WI Sbjct: 174 AGLDR-GQDPCQSDSGGPLVCDET----LQGILSWGVYPCGSAQHPAVYTQICKYMSWIN 228 Query: 623 EKTQSS 628 + +S+ Sbjct: 229 KVIRSN 234 >1AKS-B nrPDB Length = 98 Score = 95.9 bits (237), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 45/91 (49%), Positives = 66/91 (72%), Gaps = 5/91 (5%) Query: 533 NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRL 592 ++LQ + P+++N C+ Y +IT M+C G+ +GGKD+C+GDSGGP+VC NG +L Sbjct: 8 SLLQCLKAPVLSNSSCKSSYPG-QITGNMICVGFLQGGKDSCQGDSGGPVVC--NG--QL 62 Query: 593 VGITSWGEGCARREQPGVYTKVAEYMDWILE 623 GI SWG GCA++ +PGVYTKV Y++WI + Sbjct: 63 QGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQ 93 >3TK9-A nrPDB Length = 226 Score = 95.5 bits (236), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 67/231 (29%), Positives = 106/231 (45%), Gaps = 12/231 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ +Q R CGG L+ +VLTAAHC G + + G Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC-QGSSIN----VTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + F +K I H Y +++I L++L+ +T +P+ LPS Sbjct: 56 AHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQ 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C V GWG+ + LQ+V + + + +C++ + +C G + Sbjct: 116 VKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKT 174 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 + KGDSGGPLVCK GI S+G + PGVY KV+ ++ WI Sbjct: 175 QTGFKGDSGGPLVCKDVAQ----GILSYGN--KKGTPPGVYIKVSHFLPWI 219 >2J8L-A nrPDB Length = 90 Score = 95.1 bits (235), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 44/84 (52%), Positives = 55/84 (65%) Query: 292 CHSKIYPGVDFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRL 351 CHS Y DF GEEL++ K CQ+ CT +RCQFFTY+ C E K KC+L+L Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKL 61 Query: 352 SMDGSPTRIAYGTQGSSGYSLRLC 375 S +GSPT+I +G G SGY+LRLC Sbjct: 62 SSNGSPTKILHGRGGISGYTLRLC 85 Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 32/86 (37%), Positives = 42/86 (48%) Query: 111 CHRDIYKGVDMRGVNFNVSKVSSVEECQKRCTNNIRCQFFSYATQTFHKAEYRNNCLLKY 170 CH Y D G ++ S E CQK CTN +RCQFF+Y E + C LK Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKL 61 Query: 171 SPGGTPTAIKVLSNVESGFSLKPCAL 196 S G+PT I SG++L+ C + Sbjct: 62 SSNGSPTKILHGRGGISGYTLRLCKM 87 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Query: 21 CLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFLK 80 C + Y + F G ++ + + + CQ CT RC F++ PA + + E + C+LK Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCN-EGKGKCYLK 60 Query: 81 DSVTGTLPKV-HRTGAVSGHSLKQC 104 S G+ K+ H G +SG++L+ C Sbjct: 61 LSSNGSPTKILHGRGGISGYTLRLC 85 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 36/85 (42%) Query: 201 CHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLKT 260 CH + + F ++ V C+ +CT C FFT+ + C LK Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKL 61 Query: 261 SESGTPSSSTPQENTISGYSLLTCK 285 S +G+P+ ISGY+L CK Sbjct: 62 SSNGSPTKILHGRGGISGYTLRLCK 86 >1IAU-A nrPDB Length = 227 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 102/231 (44%), Gaps = 11/231 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ L + CGG LI +VLTAAHC+ + G Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + F +K I H Y ++DI L++L+ T +P+ LPS Sbjct: 56 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C V GWG + G+ + LQ+V + + + +C+ + Y + +C G E Sbjct: 116 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 175 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 K + KGDSGGPLVC GI S+G P TKV+ ++ WI Sbjct: 176 KTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGM--PPRACTKVSSFVHWI 220 >1KYN-A nrPDB Length = 235 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 71/248 (28%), Positives = 113/248 (45%), Gaps = 15/248 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG S P+ LQ++ A + CGG L+ +VLTAAHC+ + G Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWG-----SNINVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + I H Y +DI L++L + P+ LP + Sbjct: 56 AHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEG 115 Query: 511 STIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T C V GWG S +G + L++V + + + +C + + Y +R +C G + Sbjct: 116 LRPGTLCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYD-PRRQICVGDRRE 172 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 K A KGDSGGPL+C + GI S+G+ P V+T+V+ ++ WI +S Sbjct: 173 RKAAFKGDSGGPLLCNNVAH----GIVSYGKSSG--VPPEVFTRVSSFLPWIRTTMRSFK 226 Query: 630 GKAQMQSP 637 QM++P Sbjct: 227 LLDQMETP 234 >1NN6-A nrPDB Length = 228 Score = 93.6 bits (231), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/242 (30%), Positives = 112/242 (46%), Gaps = 20/242 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLT-AQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GGT P+ L++ + CGG LI +VLTAAHC R + Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC--------AGRSIT 54 Query: 450 GILNLSDITKDTPFSQIKEIII---HQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506 L +IT++ Q E+I H Y S +HDI L+KL+ + T + PS Sbjct: 55 VTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 114 Query: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 + + C V GWG + + LQ+V + L+ + C ++D+ ++ C G Sbjct: 115 QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHNLQL-CVGN 172 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 K A KGDSGGPL+C GI S+G A+ P V+T+++ Y WI + Q Sbjct: 173 PRKTKSAFKGDSGGPLLCAGVAQ----GIVSYGRSDAK--PPAVFTRISHYRPWINQILQ 226 Query: 627 SS 628 ++ Sbjct: 227 AN 228 >3RU4-E nrPDB Length = 96 Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 42/87 (48%), Positives = 54/87 (62%), Gaps = 3/87 (3%) Query: 535 LQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVG 594 LQ+ ++PL++N C K+Y KI M+CAG G +C GDSGGPLVCK NG W LVG Sbjct: 6 LQQASLPLLSNTNC-KKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWTLVG 62 Query: 595 ITSWGEGCARREQPGVYTKVAEYMDWI 621 I SWG PGVY +V ++W+ Sbjct: 63 IVSWGSSTCSTSTPGVYARVTALVNWV 89 >4X0L-C nrPDB Length = 259 Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 73/259 (28%), Positives = 114/259 (44%), Gaps = 47/259 (18%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLC-GGSLIGHQWVLTAAHCF-----DGLPLQD 443 RI+GG + G +PWQ K+ + +L G +LI QW+LT A + +D Sbjct: 14 RILGGHLDAKGSFPWQA----KMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKD 69 Query: 444 V---WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500 + +Y G L +I K +++H NY DI LIKL+ ++ E Sbjct: 70 IAPTLTLYVGKKQLVEIEK---------VVLHPNY----SQVDIGLIKLKQKVSVNERVM 116 Query: 501 PICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQR 560 PICLPSK D + + +V+GWG + + L+ V +P+ ++C + Y+ + ++ Sbjct: 117 PICLPSK-DYAEVGRVGYVSGWG-RNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEK 174 Query: 561 MV----------------CAGYKEGGKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGC 602 CAG + +D C GD+G W GI S+ + C Sbjct: 175 KTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSC 234 Query: 603 ARREQPGVYTKVAEYMDWI 621 A E GVY KV DW+ Sbjct: 235 AVAEY-GVYVKVTSIQDWV 252 >4WJG-C nrPDB Length = 315 Score = 90.1 bits (222), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 115/258 (44%), Gaps = 45/258 (17%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLC-GGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448 RI+GG + G +PWQ K+ + +L G +LI QW+LT A ++++ + Sbjct: 70 RILGGHLDAKGSFPWQA----KMVSHHNLTTGATLINEQWLLTTA--------KNLFLNH 117 Query: 449 SGILNLSDITK-------DTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKP 501 S DI +I+++++H NY DI LIKL+ ++ E P Sbjct: 118 SENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNY----SQVDIGLIKLKQKVSVNERVMP 173 Query: 502 ICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRM 561 ICLPSK D + + +V+GWG + + L+ V +P+ ++C + Y+ + ++ Sbjct: 174 ICLPSK-DYAEVGRVGYVSGWG-RNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKK 231 Query: 562 V----------------CAGYKEGGKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGCA 603 CAG + +D C GD+G W GI S+ + CA Sbjct: 232 TPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCA 291 Query: 604 RREQPGVYTKVAEYMDWI 621 E GVY KV DW+ Sbjct: 292 VAEY-GVYVKVTSIQDWV 308 >2JET-C nrPDB Length = 99 Score = 89.7 bits (221), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 3/87 (3%) Query: 535 LQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVG 594 LQ+ +P+V+ +C+K + KIT M CAG G D+C GDSGGPLVC+ +G+W L G Sbjct: 9 LQQAALPIVSEADCKKSWGS-KITDVMTCAGAS--GVDSCMGDSGGPLVCQKDGVWTLAG 65 Query: 595 ITSWGEGCARREQPGVYTKVAEYMDWI 621 I SWG G PGVY++V M W+ Sbjct: 66 IVSWGSGVCSTSTPGVYSRVTALMPWV 92 >3VGC-B nrPDB Length = 131 Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 50/136 (36%), Positives = 71/136 (52%), Gaps = 6/136 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G + G WPWQVSLQ K H CGGSLI WV+TAAHC G+ DV + +G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDK--TGFHFCGGSLINENWVVTAAHC--GVTTSDV--VVAG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + ++ +I ++ + Y N+DI L+KL ++++ +CLPS D Sbjct: 55 EFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDD 114 Query: 511 STIYTNCWVTGWGFSK 526 T C TGWG ++ Sbjct: 115 FAAGTTCVTTGWGLTR 130 >4Q7Y-A nrPDB Length = 250 Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 69/244 (28%), Positives = 112/244 (45%), Gaps = 18/244 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ S V+ Q H CGG L+ +WV++AAHCF L R Sbjct: 1 IIGGHEVTPHSRPYMAS--VRFGGQHH-CGGFLLRARWVVSAAHCFSHRDL----RTGLV 53 Query: 451 ILNLSDITKDTPFSQ---IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS- 506 +L ++ P Q I + H +Y +DI L++L + LP Sbjct: 54 VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGR 113 Query: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 + T T C V GWGF + E+ L + + ++ + C ++ + +T M+C Sbjct: 114 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRS 172 Query: 567 KEGGKDA-CKGDSGGPLVCKHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWILEK 624 + + C DSGGPLVC++ R G+ S+ G C + P VYT+V+ ++ WI + Sbjct: 173 GDSHRRGFCSADSGGPLVCRN----RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 625 TQSS 628 + S Sbjct: 229 VRRS 232 >4F4O-C nrPDB Length = 347 Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 112/258 (43%), Gaps = 45/258 (17%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAA------HCFD--GLPL 441 RI+GG+ + G +PWQ + ++ G +LI QW+LT A H D + Sbjct: 102 RIMGGSLDAKGSFPWQAKM---ISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDI 158 Query: 442 QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKP 501 R+Y G +I K +I H + DI LIKL+ + E P Sbjct: 159 APTLRLYVGKKQEVEIEK---------VIFHPD----NSTVDIGLIKLKQKVPVNERVMP 205 Query: 502 ICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRM 561 ICLPSK D + +V+GWG + ++ L+ V +P+ E+C + Y+ + ++ Sbjct: 206 ICLPSK-DYVNVGLVGYVSGWGRNANLNFTEH-LKYVMLPVADQEKCVQYYEGSTVPEKK 263 Query: 562 V----------------CAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCA 603 CAG + +D C GD+G K + W GI S+ + C Sbjct: 264 TPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSC- 322 Query: 604 RREQPGVYTKVAEYMDWI 621 R + GVY +V +DWI Sbjct: 323 RTAEYGVYVRVTSILDWI 340 >1AE5-A nrPDB Length = 225 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/231 (28%), Positives = 101/231 (43%), Gaps = 18/231 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + ++P+ S+Q RH CGG+LI ++V+TAA CF V + G Sbjct: 1 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQN-PGVSTVVLG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +L + + + + Y + +D+ L++L N T + LP + T Sbjct: 57 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 116 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 T C V GWG + G + + VN+ + ++C+ VC G Sbjct: 117 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN---------VCTGVLTRR 167 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 C GD G PLVC+ G+ V S G C R P +T+VA + DWI Sbjct: 168 GGICNGDGGTPLVCE--GLAHGVASFSLGP-CGR--GPDFFTRVALFRDWI 213 >1PPF-E nrPDB Length = 218 Score = 86.3 bits (212), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 67/234 (28%), Positives = 106/234 (45%), Gaps = 24/234 (10%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + WP+ VSLQ++ H CG +LI +V++AAHC R Sbjct: 1 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVA----NVNVRAVRV 53 Query: 451 ILNLSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 +L ++++ P Q+ + I Y +DI +++L + LP++G Sbjct: 54 VLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 113 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 C GWG I ++LQ++N+ +VT C++ VC + Sbjct: 114 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN---------VCTLVRG 163 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 621 C GDSG PLVC NG+ + GI S+ GCA P + VA++++WI Sbjct: 164 RQAGVCFGDSGSPLVC--NGL--IHGIASFVRGGCASGLYPDAFAPVAQFVNWI 213 >2JET-B nrPDB Length = 128 Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 48/133 (36%), Positives = 70/133 (52%), Gaps = 6/133 (4%) Query: 394 GTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILN 453 G ++ G WPWQVSLQ K H CGGSLI WV+TAAHC G+ DV + +G + Sbjct: 1 GEDAIPGSWPWQVSLQDK--TGFHFCGGSLISEDWVVTAAHC--GVKTSDV--VVAGEFD 54 Query: 454 LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTI 513 ++ +I ++ + + + +DI L+KL P ++E +CLP+ D Sbjct: 55 QGSDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPP 114 Query: 514 YTNCWVTGWGFSK 526 T C TGWG +K Sbjct: 115 GTVCATTGWGKTK 127 >1BBR-E nrPDB Length = 109 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 49/98 (50%), Positives = 60/98 (61%), Gaps = 7/98 (7%) Query: 530 EIQ-NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG-GK--DACKGDSGGPLVCK 585 E+Q ++LQ VN+PLV C+ + +IT M CAGYK G GK DAC+GDSGGP V K Sbjct: 4 EVQPSVLQVVNLPLVERPVCKASTR-IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMK 62 Query: 586 --HNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 +N W +GI SWGEGC R + G YT V WI Sbjct: 63 SPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 100 >1RIW-B nrPDB Length = 147 Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 11/147 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G+++ G PWQV L K + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 451 ILNLSDITKD------TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 ++ + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ P+C Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 504 LPSKGDTSTIYTNCW---VTGWGFSKE 527 LP + +++ + VTGWG KE Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKE 146 >1BBR-H nrPDB Length = 150 Score = 79.7 bits (195), Expect = 4e-15, Method: Composition-based stats. Identities = 51/147 (34%), Positives = 75/147 (51%), Gaps = 11/147 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G ++ G PWQV L K + Q LCG SLI +WVLTAAHC P + + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 451 ILNLSDIT------KDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 ++ + + K S + +I IH Y E + DIAL+KL+ P+ +++ P+C Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 504 LPSKGDTSTIYTNCW---VTGWGFSKE 527 LP K + + + VTGWG +E Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRE 146 >2HNT-F nrPDB Length = 105 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 45/94 (47%), Positives = 56/94 (59%), Gaps = 6/94 (6%) Query: 533 NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCK--HN 587 ++LQ VN+P+V C+ + +IT M CAGYK EG + DAC+GDSGGP V K N Sbjct: 4 SVLQVVNLPIVERPVCKDSTR-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFN 62 Query: 588 GMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 W +GI SWGEGC R + G YT V WI Sbjct: 63 NRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 96 >5XW8-A nrPDB Length = 133 Score = 75.5 bits (184), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 46/142 (32%), Positives = 70/142 (49%), Gaps = 11/142 (7%) Query: 385 TKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 444 T +IVGG + P+QVSL + H CGGSLI QWV++AAHC+ + Sbjct: 3 TDDDDKIVGGYTCAANSIPYQVSLN----SGSHFCGGSLINSQWVVSAAHCY-----KSR 53 Query: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504 ++ G N+ + + F +II H N+ + ++DI LIKL +P + L Sbjct: 54 IQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 113 Query: 505 PSKGDTSTIYTNCWVTGWGFSK 526 P + T C ++GWG +K Sbjct: 114 PRS--CAAAGTECLISGWGNTK 133 >2RDL-A nrPDB Length = 226 Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 114/236 (48%), Gaps = 22/236 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHL--CGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448 I+GGT P+ L++ +T + HL C G LI +V+TAAHC R Sbjct: 1 IIGGTECRPHARPYMAYLEI-VTPENHLSACSGFLIRRNFVMTAAHC--------AGRSI 51 Query: 449 SGILNLSD--ITKDT-PFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 505 + +L + + +DT ++++ H Y +DI L+KL+ N T + + Sbjct: 52 TVLLGAHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPIS 111 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 +K ++ C GWG + + LQ+V + ++ + C K ++D+ + +C G Sbjct: 112 AKSNSIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQAC-KHFEDFH-QEPQLCVG 169 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 + ++ KGDSGGPL+C G+ + GI S+ A+ P V+T+++ Y WI Sbjct: 170 NPKKIRNVYKGDSGGPLLCA--GIAQ--GIASYVLRNAK--PPSVFTRISHYRPWI 219 >3H7O-A nrPDB Length = 228 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 111/233 (47%), Gaps = 17/233 (7%) Query: 393 GGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVWRIYSGI 451 GG + + PW V+++ + CGG+++ +VLTAAHC FD P V + S Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 452 LNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQ-KPICLPSKGDT 510 L D K P+ + + + Y+ +DIA+++L PL + KP LP Sbjct: 62 L-WEDPGKSDPY--VSHVYLS-FYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFR 117 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 ++ V+G+G + + L+ + +V +EC+ +Y ++ ++ CA ++ G Sbjct: 118 PKTGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCA--QKVG 175 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQ--PGVYTKVAEYMDWI 621 GD+G P V + LVG+ ++ +R + P V+TKV Y+ WI Sbjct: 176 VSLESGDAGDPTVQQDT----LVGVAAY---FPKRPEGAPEVFTKVGSYVSWI 221 >3H7T-A nrPDB Length = 235 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 111/251 (44%), Gaps = 22/251 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG S + PW V + L ++ CGGS++ +V+TAA C DG D+ Y Sbjct: 1 IIGGKKSDITKEPWAVGV---LVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE-FQKPICLPSKGD 509 TK T K I+ + + N+ A+I+ + P+ + K I LPS Sbjct: 58 SYR---TTKGTSVMAKKIYIVRYHPLTMQNNY--AVIETEMPIKLDDKTTKKIELPSLLY 112 Query: 510 TSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQ----DYKITQRMVCA 564 T+ V+GWG + K E L + N +V + C+++Y+ D I + CA Sbjct: 113 DPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCA 172 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624 G + GD+G P V NG LVG+ S+ E P V+ +V Y +L+ Sbjct: 173 GGEYDETYIGYGDAGDPAV--QNGT--LVGVASYISSMP-SEFPSVFLRVGYY---VLDI 224 Query: 625 TQSSDGKAQMQ 635 GK + Q Sbjct: 225 KDIISGKVKPQ 235 >1DLE-A nrPDB Length = 298 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 123/281 (43%), Gaps = 56/281 (19%) Query: 397 SSWGEWPWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS 455 + + + PWQ + V ++ H C G+++ +VLTAAHCF + D + +S +++ Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFT---VDD--KEHSIKVSVG 76 Query: 456 DITKDTPFSQIKEIIIHQNYKVSEG---------NHDIALIKLQAPLNYTEFQKPICLP- 505 +D +I+ ++ H NY ++ ++D+ALIKL+ L Y + +PICLP Sbjct: 77 GEKRDL---EIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 133 Query: 506 SKGDTSTIYTNCWVTGWGFSKE---KGEIQNILQKVNIPLVTNEECQKRYQDYK------ 556 ++G T + T +E +I+ + +T +E + D K Sbjct: 134 TEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 193 Query: 557 ----------------ITQRMVCAG--YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW 598 +T R +C G + C+GDSGGPL+ + VG+ SW Sbjct: 194 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 253 Query: 599 G-----EGCARREQPGVYTK-----VAEYMDWILEKTQSSD 629 G + R++Q + + + + + W+ EK Q D Sbjct: 254 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 294 >2OK5-A nrPDB Length = 752 Score = 69.3 bits (168), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 69/279 (24%), Positives = 121/279 (43%), Gaps = 64/279 (22%) Query: 403 PWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDT 461 PWQ + V ++ H C G+++ +VLTAAHCF + D + +S +++ +D Sbjct: 479 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFT---VDD--KEHSIKVSVGGEKRDL 533 Query: 462 PFSQIKEIIIHQNYKVSEG---------NHDIALIKLQAPLNYTEFQKPICLP-SKGDTS 511 +I+ ++ H NY ++ ++D+ALIKL+ L Y + +PICLP ++G T Sbjct: 534 ---EIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 590 Query: 512 TIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEE------------------CQKRYQ 553 + T +++ E Q + V+ EE C++ Q Sbjct: 591 ALRLPPTTT----CQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 646 Query: 554 -----------DYKITQRMVCAG--YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG- 599 +T R +C G + C+GDSGGPL+ + VG+ SWG Sbjct: 647 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 706 Query: 600 ----EGCARREQPGVYTK-----VAEYMDWILEKTQSSD 629 + R++Q + + + + + W+ EK Q D Sbjct: 707 VDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 745 >2WIN-I nrPDB Length = 507 Score = 68.6 bits (166), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 72/289 (24%), Positives = 127/289 (43%), Gaps = 72/289 (24%) Query: 397 SSWGEWPWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS 455 + + + PWQ + V ++ H C G+++ +VLTAAHCF + D + +S +++ Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF---TVDD--KEHSIKVSVG 283 Query: 456 DITKDTPFSQIKEIIIHQNYKVSEG---------NHDIALIKLQAPLNYTEFQKPICLP- 505 +D +I+ ++ H NY ++ ++D+ALIKL+ L Y + +PICLP Sbjct: 284 GEKRDL---EIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 340 Query: 506 SKGDTSTIY----TNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEE-------------- 547 ++G T + T C ++K E+ Q + V+ EE Sbjct: 341 TEGTTRALRLPPTTTC-------QQQKEELLP-AQDIKALFVSEEEKKLTRKEVYIKNGD 392 Query: 548 ----CQKR------YQDYK-----ITQRMVCAG--YKEGGKDACKGDSGGPLVCKHNGMW 590 C++ Y K +T R +C G + C+GDSGGPL+ + Sbjct: 393 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRF 452 Query: 591 RLVGITSWG-----EGCARREQPGVYTK-----VAEYMDWILEKTQSSD 629 VG+ SWG + R++Q + + + + + W+ EK Q D Sbjct: 453 IQVGVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 501 >2I6S-A nrPDB Length = 517 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 102/236 (43%), Gaps = 53/236 (22%) Query: 403 PWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTP 462 PW V+++ K + C G+LI QWVLTAAHCF +WR+ G P Sbjct: 244 PWHVTIKPK---SQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG----------DP 290 Query: 463 FSQ------IKEIIIHQNYKV----SEG-----NHDIALIKLQAPLNYTEFQKPICLP-- 505 SQ I++ +I + V ++G DIAL+KL + + +PICLP Sbjct: 291 KSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCT 350 Query: 506 ---------SKGDTSTIYTNCWVTGWG----FSKEKGEIQNILQKVNI------PLVTNE 546 +G T + N + F G NI K+ + +V+ E Sbjct: 351 MEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQE 410 Query: 547 ECQ-KRYQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG 599 + D + +T + +C+G +E + CKG+SGG + + + VG+ SWG Sbjct: 411 KTMFPNLTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQVGLVSWG 465 >3H5C-B nrPDB Length = 317 Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 63/272 (23%), Positives = 108/272 (39%), Gaps = 26/272 (9%) Query: 357 PTRIAYGTQGSSGYSL----RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL 412 P + +Y + GY L + C D C TS + + PWQV L Sbjct: 60 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQ----DLPWQVKLTN-- 113 Query: 413 TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIH 472 + + CGG +I +VLT A C + R + + ++D +I + +H Sbjct: 114 SEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPLMIKITHVHVH 167 Query: 473 QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIY---TNCWVTGWGFSKEKG 529 Y G +D++L++L+ P+ P+C P K + T ++GW ++ Sbjct: 168 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW--ARNGT 225 Query: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589 ++ N L + LV EEC + + +T R C + A G + +H G Sbjct: 226 DLGNSLTTRPVTLVEGEEC-GQVLNVTVTTRTYC---ERSSVAAMHWMDGSVVTREHRGS 281 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 W L G+ + + + TKV+ Y W Sbjct: 282 WFLTGVLG-SQPVGGQAHMVLVTKVSRYSLWF 312 >3F1S-B nrPDB Length = 283 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 63/272 (23%), Positives = 108/272 (39%), Gaps = 26/272 (9%) Query: 357 PTRIAYGTQGSSGYSL----RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL 412 P + +Y + GY L + C D C TS + + PWQV L Sbjct: 19 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQ----DLPWQVKLTN-- 72 Query: 413 TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIH 472 + + CGG +I +VLT A C + R + + ++D +I + +H Sbjct: 73 SEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPLMIKITHVHVH 126 Query: 473 QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIY---TNCWVTGWGFSKEKG 529 Y G +D++L++L+ P+ P+C P K + T ++GW ++ Sbjct: 127 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW--ARNGT 184 Query: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589 ++ N L + LV EEC + + +T R C + A G + +H G Sbjct: 185 DLGNSLTTRPVTLVEGEEC-GQVLNVTVTTRTYC---ERSSVAAMHWMDGSVVTREHRGS 240 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 W L G+ + + + TKV+ Y W Sbjct: 241 WFLTGVLG-SQPVGGQAHMVLVTKVSRYSLWF 271 >2HNT-E nrPDB Length = 81 Score = 48.9 bits (115), Expect = 6e-06, Method: Composition-based stats. Identities = 24/68 (35%), Positives = 41/68 (60%), Gaps = 4/68 (5%) Query: 464 SQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCW---V 519 S +++I IH Y E + DIAL+KL+ P+ ++++ P+CLP + +++ + V Sbjct: 6 SMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRV 65 Query: 520 TGWGFSKE 527 TGWG KE Sbjct: 66 TGWGNLKE 73 >2HNT-C nrPDB Length = 70 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 25/46 (54%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF 436 IV G+++ G PWQV L K + Q LCG SLI +WVLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCL 45 >2KAI-A nrPDB Length = 80 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG PWQV++ + Q CGG L+ +WVLTAAHC D + ++ G Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQ---CGGVLVNPKWVLTAAHC-----KNDNYEVWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS 478 NL + F + H + +S Sbjct: 53 RHNLFENENTAQFFGVTADFPHPGFNLS 80 >1EPT-B nrPDB Length = 82 Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 2/74 (2%) Query: 453 NLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTST 512 N+ + + F +II H N+ + ++DI LIKL +P + LP + Sbjct: 11 NIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS--CAA 68 Query: 513 IYTNCWVTGWGFSK 526 T C ++GWG +K Sbjct: 69 AGTECLISGWGNTK 82 >4LG8-A nrPDB Length = 354 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 13/87 (14%) Query: 207 QHLAFSDVDVARVL---TPDAFVCRTICT-YHPNCLFFTFYT-----NVWKIESQRNVCL 257 Q+ AFSD+ RVL T + C C +HP+ L F T +W ++ + NV Sbjct: 178 QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVAN 237 Query: 258 LKTSESGTPSSSTPQENTISGYSLLTC 284 SG +S EN GY L T Sbjct: 238 FP-GHSGPITSIAFSEN---GYYLATA 260 >5Z56-q nrPDB Length = 504 Score = 30.0 bits (66), Expect = 3.5, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 13/87 (14%) Query: 207 QHLAFSDVDVARVLTP---DAFVCRTICT-YHPNCLFFTFYT-----NVWKIESQRNVCL 257 Q+ AFSD+ RVLT + C C +HP+ L F T +W ++ + NV Sbjct: 328 QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVAN 387 Query: 258 LKTSESGTPSSSTPQENTISGYSLLTC 284 SG +S EN GY L T Sbjct: 388 FP-GHSGPITSIAFSEN---GYYLATA 410 >5BPZ-A nrPDB Length = 169 Score = 29.6 bits (65), Expect = 4.1, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 62 FLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAV 96 + + DME+ F L DS TGT P+VH+T V Sbjct: 97 LMAEGELKDMEQFFDD-LADSFTGTEPEVHKTSVV 130 >4KFN-A nrPDB Length = 501 Score = 28.9 bits (63), Expect = 6.5, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 26/56 (46%) Query: 114 DIYKGVDMRGVNFNVSKVSSVEECQKRCTNNIRCQFFSYATQTFHKAEYRNNCLLK 169 D YK + N SKV S EC+++ T N + + Y F+ +Y N LK Sbjct: 16 DSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLK 71 >1HKY-A nrPDB Length = 86 Score = 28.5 bits (62), Expect = 9.6, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%) Query: 299 GVDF-GGEELNVTFVKGVNVCQETCTKMIRCQFFTYS 334 GV F GG+ ++ CQE C K +C+FFT + Sbjct: 17 GVSFTGGKAISEAKAASSQACQELCEKDAKCRFFTLA 53 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6I44-A nrPDB 991 0.0 2F83-A nrPDB 924 0.0 5TJX-A nrPDB 401 e-112 5GVT-A nrPDB 362 e-100 6AOD-C nrPDB 328 4e-90 3W94-A nrPDB 303 2e-82 1F7Z-A nrPDB 300 2e-81 4DGJ-A nrPDB 298 5e-81 4AN7-A nrPDB 295 4e-80 5UGG-A nrPDB 293 2e-79 1EKB-B nrPDB 293 2e-79 5C67-A nrPDB 291 4e-79 5FXL-A nrPDB 291 6e-79 4WWY-A nrPDB 291 7e-79 2F91-A nrPDB 290 1e-78 1UTJ-A nrPDB 290 1e-78 4MPW-A nrPDB 289 2e-78 3T2N-A nrPDB 287 1e-77 3LC3-A nrPDB 286 2e-77 1LTO-A nrPDB 286 2e-77 3E0N-B nrPDB 286 3e-77 1X7A-C nrPDB 284 7e-77 4DUR-A nrPDB 283 1e-76 3DFJ-A nrPDB 283 1e-76 3P8G-A nrPDB 283 2e-76 1P57-B nrPDB 283 2e-76 3K65-B nrPDB 282 4e-76 4H4F-A nrPDB 282 4e-76 1FXY-A nrPDB 281 6e-76 1BRU-P nrPDB 279 3e-75 3NXP-A nrPDB 279 3e-75 1A0J-A nrPDB 279 3e-75 1MKW-K nrPDB 278 4e-75 1PYT-D nrPDB 278 6e-75 4Z6A-H nrPDB 275 4e-74 1KIG-H nrPDB 275 4e-74 4KKD-A nrPDB 274 6e-74 2OQ5-A nrPDB 273 1e-73 1YC0-A nrPDB 273 2e-73 4NZQ-A nrPDB 273 2e-73 2OCV-B nrPDB 272 3e-73 1ETT-H nrPDB 271 6e-73 1EUF-A nrPDB 271 7e-73 1FI8-A nrPDB 271 8e-73 2CGA-A nrPDB 270 1e-72 1C5M-D nrPDB 269 2e-72 1SC8-U nrPDB 269 2e-72 1FIZ-A nrPDB 269 3e-72 1SGF-G nrPDB 268 6e-72 1BDA-A nrPDB 267 1e-71 4IW4-E nrPDB 267 1e-71 1VR1-H nrPDB 266 2e-71 2V35-A nrPDB 266 2e-71 2EEK-A nrPDB 265 3e-71 4NFE-A nrPDB 265 5e-71 3F6U-H nrPDB 265 5e-71 2R0L-A nrPDB 264 8e-71 2TLD-E nrPDB 264 9e-71 1FIW-A nrPDB 263 2e-70 1IAU-A nrPDB 261 5e-70 1ELT-A nrPDB 260 1e-69 1A5I-A nrPDB 259 3e-69 5LHN-A nrPDB 258 4e-69 1SPJ-A nrPDB 257 1e-68 5FCR-A nrPDB 256 3e-68 6QHB-A nrPDB 255 3e-68 5MS3-A nrPDB 254 1e-67 3G01-A nrPDB 253 2e-67 1NPM-A nrPDB 252 3e-67 4XDE-A nrPDB 252 3e-67 1FDP-A nrPDB 252 3e-67 3QUM-P nrPDB 252 4e-67 1FON-A nrPDB 249 2e-66 1AO5-A nrPDB 249 2e-66 2PSX-A nrPDB 249 4e-66 1NN6-A nrPDB 248 7e-66 3TK9-A nrPDB 248 7e-66 5TO3-B nrPDB 244 6e-65 1Q3X-A nrPDB 244 9e-65 4IGD-A nrPDB 244 1e-64 3BSQ-A nrPDB 244 1e-64 1SGF-A nrPDB 244 1e-64 1TON-A nrPDB 243 2e-64 1FUJ-A nrPDB 242 2e-64 4GSO-A nrPDB 242 2e-64 1KYN-A nrPDB 242 5e-64 4FXG-H nrPDB 241 6e-64 2AIQ-A nrPDB 240 1e-63 4DJZ-B nrPDB 240 2e-63 1GPZ-A nrPDB 239 3e-63 5ZFH-A nrPDB 239 4e-63 1ZJK-A nrPDB 239 4e-63 1MD7-A nrPDB 238 4e-63 2QY0-B nrPDB 237 1e-62 1MZD-A nrPDB 236 2e-62 1ORF-A nrPDB 236 3e-62 5O32-I nrPDB 235 4e-62 3S9B-A nrPDB 235 4e-62 4BXW-A nrPDB 235 6e-62 4Q7Y-A nrPDB 234 8e-62 3RP2-A nrPDB 234 1e-61 4E7N-A nrPDB 233 2e-61 2OLG-A nrPDB 233 2e-61 2ZKS-A nrPDB 233 2e-61 1YM0-A nrPDB 231 7e-61 1BQY-A nrPDB 230 1e-60 5UBM-A nrPDB 229 2e-60 2XRC-A nrPDB 229 3e-60 5KWM-A nrPDB 229 4e-60 2B9L-A nrPDB 228 6e-60 1ELV-A nrPDB 228 6e-60 1OP0-A nrPDB 227 9e-60 1GVZ-A nrPDB 227 1e-59 2XXL-A nrPDB 227 1e-59 2BDH-A nrPDB 226 2e-59 2RDL-A nrPDB 226 3e-59 1EQ9-A nrPDB 226 3e-59 1AZZ-A nrPDB 226 3e-59 6BQM-A nrPDB 224 1e-58 3I77-A nrPDB 224 1e-58 3S69-A nrPDB 222 4e-58 4J1Y-A nrPDB 220 2e-57 2FMJ-A nrPDB 219 2e-57 3BEU-A nrPDB 218 7e-57 5LPF-A nrPDB 216 2e-56 4WJG-C nrPDB 216 3e-56 1M9U-A nrPDB 213 2e-55 5XRF-A nrPDB 213 2e-55 4X0L-C nrPDB 213 2e-55 4F4O-C nrPDB 212 3e-55 1PQ7-A nrPDB 212 4e-55 2ASU-B nrPDB 209 4e-54 4LK4-A nrPDB 206 3e-53 1AE5-A nrPDB 205 6e-53 1SI5-H nrPDB 201 9e-52 2HLC-A nrPDB 201 9e-52 1PPF-E nrPDB 200 2e-51 3F1S-B nrPDB 176 2e-44 2PKA-B nrPDB 174 1e-43 2WIN-I nrPDB 172 3e-43 3H7O-A nrPDB 171 7e-43 3H5C-B nrPDB 170 1e-42 1DLE-A nrPDB 167 1e-41 3H7T-A nrPDB 167 2e-41 5XW8-A nrPDB 166 3e-41 2OK5-A nrPDB 166 3e-41 1RIW-B nrPDB 153 2e-37 3VGC-B nrPDB 153 3e-37 2JET-B nrPDB 152 4e-37 1BBR-H nrPDB 151 7e-37 2J8L-A nrPDB 147 1e-35 2I6S-A nrPDB 141 1e-33 1AKS-B nrPDB 136 3e-32 1BBR-E nrPDB 127 2e-29 2HNT-F nrPDB 125 4e-29 2JET-C nrPDB 122 4e-28 3RU4-E nrPDB 122 6e-28 2KAI-A nrPDB 99 5e-21 2HNT-E nrPDB 82 6e-16 2HNT-C nrPDB 79 8e-15 Sequences not found previously or not previously below threshold: 1EPT-B nrPDB 105 8e-23 1P3E-A nrPDB 41 0.001 1HKY-A nrPDB 33 0.34 4JCN-A nrPDB 31 1.3 5ILB-A nrPDB 30 2.7 4FLN-A nrPDB 30 2.7 5E5H-A nrPDB 30 4.6 2YIL-A nrPDB 30 4.8 3ISR-A nrPDB 29 5.0 6H0D-A nrPDB 29 5.1 3AK5-A nrPDB 29 5.6 >6I44-A nrPDB Length = 627 Score = 991 bits (2562), Expect = 0.0, Method: Composition-based stats. Identities = 611/619 (98%), Positives = 612/619 (98%) Query: 20 GCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFL 79 GCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFL Sbjct: 9 GCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFL 68 Query: 80 KDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQK 139 KDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQK Sbjct: 69 KDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQK 128 Query: 140 RCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEI 199 RCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEI Sbjct: 129 RCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEI 188 Query: 200 GCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLK 259 GCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLK Sbjct: 189 GCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLK 248 Query: 260 TSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQ 319 TSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQ Sbjct: 249 TSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQ 308 Query: 320 ETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGD 379 ETCTKMIRCQFFTYSLLPEDCK E CKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGD Sbjct: 309 ETCTKMIRCQFFTYSLLPEDCKAEACKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGD 368 Query: 380 NSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGL 439 NSVCTTKTSTRIVGGT SSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGL Sbjct: 369 NSVCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGL 428 Query: 440 PLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQ 499 PLQDVWRIYSGIL LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPL YTEFQ Sbjct: 429 PLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQ 488 Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQ 559 KPICLPSKGDTSTIYTNCWVTGWGFS E GEIQNILQKVNIPLVTNEECQKRYQDYKITQ Sbjct: 489 KPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQ 548 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619 RMVCAGYKEGGKDACKGD+GGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD Sbjct: 549 RMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 608 Query: 620 WILEKTQSSDGKAQMQSPA 638 WILEKTQSSDGKAQMQSPA Sbjct: 609 WILEKTQSSDGKAQMQSPA 627 >2F83-A nrPDB Length = 625 Score = 924 bits (2387), Expect = 0.0, Method: Composition-based stats. Identities = 367/627 (58%), Positives = 466/627 (74%), Gaps = 3/627 (0%) Query: 1 MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLF 60 MI Q +FI LF +VS C+TQL ++ F GGD+ +++TP+A+YCQ+ CT+HPRCLLF Sbjct: 1 MIFLYQVVHFI-LFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLF 59 Query: 61 SFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVD 120 +F S D + F C LKDSVT TLP+V+RT A+SG+S KQC HQISAC++DIY +D Sbjct: 60 TFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLD 119 Query: 121 MRGVNFNVSKVSSVEECQKRCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIK 180 M+G+N+N S S +ECQ+RCT+++ C FF+YAT+ F E+RN CLLK++ GTPT I Sbjct: 120 MKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRIT 179 Query: 181 VLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFF 240 L V SGFSLK CALS + C +IF + F+D ++ V+ PDAFVC ICT+HP CLFF Sbjct: 180 KLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFF 239 Query: 241 TFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGV 300 TF++ W ESQRN+CLLKTSESG PS+ + +SG+SL +C+ ++P CHS Y Sbjct: 240 TFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDT 299 Query: 301 DFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRI 360 DF GEEL++ K CQ+ CT +RCQFFTY+ C E K KC+L+LS +GSPT+I Sbjct: 300 DFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKI 359 Query: 361 AYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG 420 +G G SGY+LRLC DN CTTK RIVGGT S GEWPWQV+L QRHLCG Sbjct: 360 LHGRGGISGYTLRLCKM-DNE-CTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCG 417 Query: 421 GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG 480 GS+IG+QW+LTAAHCF G+ + R+YSGILN S+I +DT F ++EIIIH YK++E Sbjct: 418 GSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAES 477 Query: 481 NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI 540 +DIAL+KL+ +NYT+ Q+PICLPSKGD + IYT+CWVTGWG+ K + +IQN LQK I Sbjct: 478 GYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKI 537 Query: 541 PLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE 600 PLVTNEECQKRY+ +KIT +M+CAGY+EGGKDACKGDSGGPL CKHN +W LVGITSWGE Sbjct: 538 PLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE 597 Query: 601 GCARREQPGVYTKVAEYMDWILEKTQS 627 GCA+RE+PGVYT V EY+DWILEKTQ+ Sbjct: 598 GCAQRERPGVYTNVVEYVDWILEKTQA 624 >5TJX-A nrPDB Length = 263 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 259/263 (98%), Positives = 259/263 (98%) Query: 376 NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 435 NTGDNSVCTTKTSTRIVGGT SSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC Sbjct: 1 NTGDNSVCTTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 60 Query: 436 FDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNY 495 FDGLPLQDVWRIYSGIL LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPL Y Sbjct: 61 FDGLPLQDVWRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEY 120 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY 555 TEFQKPI LPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY Sbjct: 121 TEFQKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY 180 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 615 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA Sbjct: 181 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 240 Query: 616 EYMDWILEKTQSSDGKAQMQSPA 638 EYMDWILEKTQSSDGKAQMQSPA Sbjct: 241 EYMDWILEKTQSSDGKAQMQSPA 263 >5GVT-A nrPDB Length = 250 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 198/248 (79%), Positives = 223/248 (89%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGTN+S GEWPWQVSLQVKL +Q HLCGGS+IG QWVLTAAHCFDG+P DVWRIY G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 IL+LS+ITK+TP S+IKE+IIHQ YKVSEGN+DIALIKLQ PLNYTEFQKPI LPSK DT Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 +TIYTNCWVTGWG++KE+GE QNILQK IPLV NEECQK+Y+DY I ++M+CAGYKEGG Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGG 180 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDG 630 DACKGDSGGPLVCKH+G W+LVGITSWGEGCAR++QPGVYTKV+EYMDWILEKTQSSD Sbjct: 181 TDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQSSDV 240 Query: 631 KAQMQSPA 638 +A S A Sbjct: 241 RALETSSA 248 >6AOD-C nrPDB Length = 245 Score = 328 bits (841), Expect = 4e-90, Method: Composition-based stats. Identities = 157/237 (66%), Positives = 192/237 (81%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGT S GEWPWQV+L QRHLCGGS+IG+QW+LTAAHCF G+ + R+YSG Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 IL S+I +DT F ++EIIIH YK++E +DIAL+KL+ + YT+ Q+PI LPSKGD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 + IYT+CWVTGWG+ K + +IQN LQK IPLVTNEECQKRY+ +KIT +M+CAGY+EGG Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 KDACKGD+GGPL CKHN +W LVGITSWGEGCA+RE+PGVYT V EY+DWILEKTQ+ Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQA 237 >3W94-A nrPDB Length = 235 Score = 303 bits (775), Expect = 2e-82, Method: Composition-based stats. Identities = 101/236 (42%), Positives = 140/236 (59%), Gaps = 5/236 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIYS 449 +VGG N+ G WPW VSL + RH CG SLIG W+LTAAHC G W Sbjct: 1 VVGGVNAEKGAWPWMVSLHWR---GRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 450 GILNLSD-ITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G+ S +++ Q+ III++NY DIA++ LQ P+N+TE+ P+CL S+ Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 C++ GWG E G + +ILQ+ +PLV +ECQ+ +Y T M+CAGY E Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPE 177 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624 GG D+C+GDSGGPL+C + W L+G+TS+G GC R E+PG Y +V+ + WI E Sbjct: 178 GGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAET 233 >1F7Z-A nrPDB Length = 233 Score = 300 bits (767), Expect = 2e-81, Method: Composition-based stats. Identities = 94/249 (37%), Positives = 132/249 (53%), Gaps = 17/249 (6%) Query: 381 SVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLP 440 IVGG P+QVSL + H CGGSLI QWV++AAHC+ Sbjct: 1 EAFPVDDDDAIVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCY---- 52 Query: 441 LQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500 + ++ G N++ + + F +II H N+ N+DI LIKL +P+ Sbjct: 53 -KSRIQVRLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVA 111 Query: 501 PICLPSKGDTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQ 559 + LPS + T C ++GWG + G ++LQ ++ PL+ +C+ Y KIT Sbjct: 112 TVALPS--SCAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPG-KITD 168 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619 MVC G+ EGGKD+C+GDSGGP+VC L GI SWG GCA + PGVYTKV Y+D Sbjct: 169 NMVCVGFLEGGKDSCQGDSGGPVVCNG----ELQGIVSWGYGCALPDNPGVYTKVCNYVD 224 Query: 620 WILEKTQSS 628 WI + ++ Sbjct: 225 WIQDTIAAN 233 >4DGJ-A nrPDB Length = 235 Score = 298 bits (763), Expect = 5e-81, Method: Composition-based stats. Identities = 95/235 (40%), Positives = 143/235 (60%), Gaps = 5/235 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPL-QDVWRIYS 449 IVGG+++ G WPW V L R LCG SL+ W+++AAHC G L W Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDD---RLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 450 GILNLSDITKDTPF-SQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G+ S++T I EI+I+ +Y ++DIA++ L+ +NYT++ +PI LP + Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 NC + GWG +G +ILQ+ ++PL++NE CQ++ +Y IT+ M+CAGY+E Sbjct: 118 QVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEE 177 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 GG D+C+GDSGGPL+C+ N W L G+TS+G CA +PGVY +V+ + +WI Sbjct: 178 GGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQS 232 >4AN7-A nrPDB Length = 231 Score = 295 bits (756), Expect = 4e-80, Method: Composition-based stats. Identities = 90/246 (36%), Positives = 137/246 (55%), Gaps = 17/246 (6%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 443 T +IVGG + P+QVSL + H CGGSLI QWV++AAHC+ + Sbjct: 2 PTDDDDKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCY-----KS 52 Query: 444 VWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPIC 503 ++ G N+ + + F +II H N+ + ++DI LIKL +P + Sbjct: 53 RIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 112 Query: 504 LPSKGDTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMV 562 LP + T C ++GWG +K G ++LQ + P++++ C+ Y +IT M+ Sbjct: 113 LPR--SCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPG-QITGNMI 169 Query: 563 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWIL 622 C G+ EGGKD+C+GDSGGP+VC +L GI SWG GCA++ +PGVYTKV Y++WI Sbjct: 170 CVGFLEGGKDSCQGDSGGPVVCNG----QLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQ 225 Query: 623 EKTQSS 628 + ++ Sbjct: 226 QTIAAN 231 >5UGG-A nrPDB Length = 251 Score = 293 bits (750), Expect = 2e-79, Method: Composition-based stats. Identities = 86/257 (33%), Positives = 136/257 (52%), Gaps = 10/257 (3%) Query: 373 RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTA 432 + G V K R+VGG + WPWQVSL+ + H CGG+LI +WVLTA Sbjct: 4 PSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTA 61 Query: 433 AHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAP 492 AHC + P +++ G ++ ++ + + DIAL+KL +P Sbjct: 62 AHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSP 115 Query: 493 LNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-R 551 T+ P CLPS T C++TGWG ++ +L++ +P++ N+ C + Sbjct: 116 AVITDKVIPACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYE 174 Query: 552 YQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVY 611 + + ++ +CAG+ GG D+C+GDSGGPLVC + L G+TSWG GCAR +PGVY Sbjct: 175 FLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVY 234 Query: 612 TKVAEYMDWILEKTQSS 628 +V+ ++ WI +++ Sbjct: 235 VRVSRFVTWIEGVMRNN 251 >1EKB-B nrPDB Length = 235 Score = 293 bits (749), Expect = 2e-79, Method: Composition-based stats. Identities = 92/235 (39%), Positives = 144/235 (61%), Gaps = 5/235 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPL-QDVWRIYS 449 IVGG++S G WPW V+L + +CG SL+ W+++AAHC G + W+ Sbjct: 1 IVGGSDSREGAWPWVVALYFDD---QQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 450 GILNLSDITKDT-PFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G+ S++T I +I+I+ +Y N+DIA++ L+ +NYT++ +PICLP + Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 C + GWG +G ++LQ+ ++PL++NE+CQ++ +Y IT+ MVCAGY+ Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEA 177 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 GG D+C+GDSGGPL+C+ N W L G+TS+G CA +PGVY +V + +WI Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQS 232 >5C67-A nrPDB Length = 224 Score = 291 bits (746), Expect = 4e-79, Method: Composition-based stats. Identities = 89/240 (37%), Positives = 129/240 (53%), Gaps = 17/240 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG P+QVSL + H CGGSLI QWV++AAHC+ + ++ G Sbjct: 1 IVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVSAAHCY-----KTRIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + F +II H Y ++DI LIKL +P I LP+ Sbjct: 52 EHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA--P 109 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T C ++GWG + G + + L+ ++ P++T EC+ Y KIT M C G+ EG Sbjct: 110 PAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG-KITNSMFCVGFLEG 168 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 GKD+C+ D+GGP+VC +L G+ SWG GCA + +PGVYTKV Y+DWI + ++ Sbjct: 169 GKDSCQRDAGGPVVCNG----QLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 224 >5FXL-A nrPDB Length = 246 Score = 291 bits (745), Expect = 6e-79, Method: Composition-based stats. Identities = 91/246 (36%), Positives = 137/246 (55%), Gaps = 17/246 (6%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 443 +IVGG P+QVSL + H CGGSLI QWV++AAHC+ + Sbjct: 17 PVDDDDKIVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCY-----KS 67 Query: 444 VWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPIC 503 ++ G N++ + + F + I+H +Y + N+DI LIKL++ + I Sbjct: 68 GIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASIS 127 Query: 504 LPSKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQDYKITQRMV 562 LP+ ++ T C ++GWG +K G ++L+ + P++++ C+ Y +IT M Sbjct: 128 LPT--SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPG-QITSNMF 184 Query: 563 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWIL 622 CAGY EGGKD+C+GDSGGP+VC L GI SWG GCA++ +PGVYTKV Y+ WI Sbjct: 185 CAGYLEGGKDSCQGDSGGPVVCSGK----LQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK 240 Query: 623 EKTQSS 628 + S+ Sbjct: 241 QTIASN 246 >4WWY-A nrPDB Length = 224 Score = 291 bits (745), Expect = 7e-79, Method: Composition-based stats. Identities = 88/240 (36%), Positives = 128/240 (53%), Gaps = 17/240 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG N P+QVSL + H CGGSLI QWV++A HC+ + ++ G Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCY-----KSRIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + F +II H Y N+DI LIKL + I LP+ Sbjct: 52 EHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTA--P 109 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T C ++GWG + G + + LQ ++ P+++ +C+ Y KIT M C G+ EG Sbjct: 110 PATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPG-KITSNMFCVGFLEG 168 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 GKD+C+ DSGGP+VC +L G+ SWG+GCA++ +PGVYTKV Y+ WI ++ Sbjct: 169 GKDSCQRDSGGPVVCNG----QLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 224 >2F91-A nrPDB Length = 237 Score = 290 bits (742), Expect = 1e-78, Method: Composition-based stats. Identities = 96/235 (40%), Positives = 142/235 (60%), Gaps = 5/235 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTA-QRHLCGGSLIGHQWVLTAAHCFDGLPLQDV--WRI 447 IVGGT+++ GE+P+Q+S Q H CG S+ + +TA HC G ++ +I Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 +G L++S + +II+H+N+ + ++DI+L+KL L + + PI LP + Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 G T+T + VTGWG + E G ++LQKV +PLV++E+C+ Y +I M+CAG Sbjct: 121 GHTAT--GDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWIL 622 EGGKD+C+GDSGGPL G L GI SWG GCAR PGVYT+V+ ++DWI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK 233 >1UTJ-A nrPDB Length = 242 Score = 290 bits (742), Expect = 1e-78, Method: Composition-based stats. Identities = 90/240 (37%), Positives = 120/240 (50%), Gaps = 16/240 (6%) Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 +IVGG P QVSL + H CGGSL+ WV++AAHC+ + + Sbjct: 18 DDKIVGGYECKPYSQPHQVSL----NSGYHFCGGSLVNENWVVSAAHCY-----KSRVEV 68 Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 G N+ F +I H NY ++DI LIKL P + +P+ LP+ Sbjct: 69 RLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPT- 127 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + T C V+GWG + N LQ +NIP+++ +C Y IT M CAGY Sbjct: 128 -SCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGM-ITNAMFCAGYL 185 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 EGGKD+C+GDSGGP+VC L G+ SWG GCA PGVY KV + DW+ S Sbjct: 186 EGGKDSCQGDSGGPVVCNG----ELQGVVSWGYGCAEPGNPGVYAKVCIFNDWLTSTMAS 241 >4MPW-A nrPDB Length = 245 Score = 289 bits (740), Expect = 2e-78, Method: Composition-based stats. Identities = 92/241 (38%), Positives = 131/241 (54%), Gaps = 14/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + +WPWQVSL+V H CGGSLI QWVLTAAHC G ++D+ + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + +D + II+H + ++ DIAL++L+ P+ + + LP +T Sbjct: 60 LREQHLYYQD-QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASET 118 Query: 511 STIYTNCWVTGWGFSKEKGEIQNI--LQKVNIPLVTNEECQKRYQDYK--------ITQR 560 CWVTGWG + L++V +P++ N C +Y + Sbjct: 119 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 178 Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 M+CAG +D+C+GDSGGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+DW Sbjct: 179 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 236 Query: 621 I 621 I Sbjct: 237 I 237 >3T2N-A nrPDB Length = 372 Score = 287 bits (734), Expect = 1e-77, Method: Composition-based stats. Identities = 106/285 (37%), Positives = 154/285 (54%), Gaps = 23/285 (8%) Query: 364 TQGSSGYSLRL--CNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGG 421 G L + G + RIVGG ++S G WPWQVSL+ HLCGG Sbjct: 93 CDCPRGRFLAAICQDCGRRKL----PVDRIVGGRDTSLGRWPWQVSLRYD---GAHLCGG 145 Query: 422 SLIGHQWVLTAAHCFDGLPLQ-DVWRIYSGILNLSDITKDTPFSQIKEIIIHQNY----- 475 SL+ WVLTAAHCF WR+++G + + ++ ++ H Y Sbjct: 146 SLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQ--LGVQAVVYHGGYLPFRD 203 Query: 476 -KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNI 534 E ++DIAL+ L +PL TE+ +P+CLP+ G C VTGWG ++ G+ + Sbjct: 204 PNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV 263 Query: 535 LQKVNIPLVTNEECQ-KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKH----NGM 589 LQ+ +P+++N+ C + +I +M CAGY EGG DAC+GDSGGP VC+ Sbjct: 264 LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPR 323 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQM 634 WRL GI SWG GCA ++PGVYTKV+++ +WI + ++ + M Sbjct: 324 WRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGM 368 >3LC3-A nrPDB Length = 235 Score = 286 bits (732), Expect = 2e-77, Method: Composition-based stats. Identities = 92/240 (38%), Positives = 136/240 (56%), Gaps = 11/240 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG ++ G++PWQV L K+ A CGGS++ +W++TAAHC + + +G Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDA---FCGGSIVNEKWIVTAAHCVETGVK---ITVVAG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKV--SEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 N+ + + II H NY ++ NHDIAL++L PL + PIC+ K Sbjct: 55 EHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKE 114 Query: 509 DT--STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 T + + +V+GWG KG +LQ + +PLV C + + I M CAG+ Sbjct: 115 YTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRS-TKFTIYNNMFCAGF 173 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 EGG+D+C+GDSGGP V + G L GI SWGE CA + + G+YTKV+ Y++WI EKT+ Sbjct: 174 HEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >1LTO-A nrPDB Length = 245 Score = 286 bits (732), Expect = 2e-77, Method: Composition-based stats. Identities = 94/241 (39%), Positives = 132/241 (54%), Gaps = 14/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + +WPWQVSL+V+ H CGGSLI QWVLTAAHC G ++D+ + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCL-GPDVKDLATLRVQ 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + +D + II+H + + + DIAL++L+ P+N + + LP +T Sbjct: 60 LREQHLYYQD-QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASET 118 Query: 511 STIYTNCWVTGWGFSKEKGEIQNI--LQKVNIPLVTNEECQKRYQDYK--------ITQR 560 CWVTGWG + L++V +P++ N C +Y I Sbjct: 119 FPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDD 178 Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 M+CAG +D+CKGDSGGPLVCK NG W G+ SW EGCA+ +PG+YT+V Y+DW Sbjct: 179 MLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLDW 236 Query: 621 I 621 I Sbjct: 237 I 237 >3E0N-B nrPDB Length = 271 Score = 286 bits (731), Expect = 3e-77, Method: Composition-based stats. Identities = 98/255 (38%), Positives = 143/255 (56%), Gaps = 12/255 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I GG+++ G+WPWQVS+ + H+CGGSL+ QWVL+AAHCF ++ + + G Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 L ++D S +K+II H +Y DIAL++L P+ ++ + +PI LP+ + Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 511 STIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY-------QDYKITQRM 561 +C VTGWG + LQ++ +PL++ E C Y + + + + M Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDM 177 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 VCAGY EGGKDAC+GDSGGPL C G+W L GI SWG+ C R +PGVYT + Y WI Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 Query: 622 LEKTQSSDGKAQMQS 636 K + Q+ Sbjct: 238 QSKVTELQPRVVPQT 252 >1X7A-C nrPDB Length = 235 Score = 284 bits (727), Expect = 7e-77, Method: Composition-based stats. Identities = 95/240 (39%), Positives = 135/240 (56%), Gaps = 11/240 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG N+ G++PWQV L K+ A CGGS+I +WV+TAAHC + + +G Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDA---FCGGSIINEKWVVTAAHCIE---PGVKITVVAG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYK--VSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 N + + I H +Y V++ +HDIAL++L PL + PIC+ K Sbjct: 55 EYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKE 114 Query: 509 DT--STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 T + + +V+GWG +G ILQ + +PLV C + + I M CAG+ Sbjct: 115 YTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRS-TKFTIYSNMFCAGF 173 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 EGGKD+C+GDSGGP V + G L GI SWGE CA + + G+YTKV+ Y++WI EKT+ Sbjct: 174 HEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >4DUR-A nrPDB Length = 791 Score = 283 bits (725), Expect = 1e-76, Method: Composition-based stats. Identities = 86/257 (33%), Positives = 136/257 (52%), Gaps = 10/257 (3%) Query: 373 RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTA 432 + G V K R+VGG + WPWQVSL+ + H CGG+LI +WVLTA Sbjct: 544 PSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRF--GMHFCGGTLISPEWVLTA 601 Query: 433 AHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAP 492 AHC + P +++ G ++ ++ + + DIAL+KL +P Sbjct: 602 AHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSP 655 Query: 493 LNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-R 551 T+ P CLPS T C++TGWG ++ +L++ +P++ N+ C + Sbjct: 656 AVITDKVIPACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYE 714 Query: 552 YQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVY 611 + + ++ +CAG+ GG D+C+GDSGGPLVC + L G+TSWG GCAR +PGVY Sbjct: 715 FLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVY 774 Query: 612 TKVAEYMDWILEKTQSS 628 +V+ ++ WI +++ Sbjct: 775 VRVSRFVTWIEGVMRNN 791 >3DFJ-A nrPDB Length = 263 Score = 283 bits (725), Expect = 1e-76, Method: Composition-based stats. Identities = 97/244 (39%), Positives = 140/244 (57%), Gaps = 12/244 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I GG+++ G+WPWQVS+ + H+CGGSL+ QWVL+AAHCF ++ + + G Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 L ++D S +K+II H +Y DIAL++L P+ ++ + +PI LP+ + Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 511 STIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY-------QDYKITQRM 561 +C VTGWG + LQ++ +PL++ E C Y + + + + M Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDM 177 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 VCAGY EGGKDAC+GDSGGPL C G+W L GI SWG+ C R +PGVYT + Y WI Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 Query: 622 LEKT 625 K Sbjct: 238 QSKV 241 >3P8G-A nrPDB Length = 241 Score = 283 bits (724), Expect = 2e-76, Method: Composition-based stats. Identities = 93/242 (38%), Positives = 134/242 (55%), Gaps = 10/242 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDG-----LPLQDVW 445 +VGGT++ GEWPWQVSL Q H+CG SLI W+++AAHC+ W Sbjct: 1 VVGGTDADEGEWPWQVSLHAL--GQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 446 RIYSGILNLSDIT-KDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504 + G+ + S + ++K II H + ++DIAL++L+ P Y+ +PICL Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 564 P WVTGWG ++ G ILQK I ++ C+ +IT RM+C Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQ-QITPRMMCV 177 Query: 565 GYKEGGKDACKGDSGGPL-VCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 G+ GG D+C+GDSGGPL + +G G+ SWG+GCA+R +PGVYT++ + DWI E Sbjct: 178 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 237 Query: 624 KT 625 T Sbjct: 238 NT 239 >1P57-B nrPDB Length = 255 Score = 283 bits (724), Expect = 2e-76, Method: Composition-based stats. Identities = 102/256 (39%), Positives = 148/256 (57%), Gaps = 17/256 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIYS 449 IVGG ++S G WPWQVSL+ HLCGGSL+ WVLTAAHCF WR+++ Sbjct: 1 IVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNY------KVSEGNHDIALIKLQAPLNYTEFQKPIC 503 G + + ++ ++ H Y E ++DIAL+ L +PL TE+ +P+C Sbjct: 58 GAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 115 Query: 504 LPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-KRYQDYKITQRMV 562 LP+ G C VTGWG ++ G+ +LQ+ +P+++N+ C + +I +M Sbjct: 116 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 175 Query: 563 CAGYKEGGKDACKGDSGGPLVCKH----NGMWRLVGITSWGEGCARREQPGVYTKVAEYM 618 CAGY EGG DAC+GDSGGP VC+ WRL GI SWG GCA ++PGVYTKV+++ Sbjct: 176 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 235 Query: 619 DWILEKTQSSDGKAQM 634 +WI + ++ + M Sbjct: 236 EWIFQAIKTHSEASGM 251 >3K65-B nrPDB Length = 308 Score = 282 bits (721), Expect = 4e-76, Method: Composition-based stats. Identities = 96/274 (35%), Positives = 138/274 (50%), Gaps = 23/274 (8%) Query: 374 LCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAA 433 L + + + + RIV G+++ G PWQV L K + Q LCG SLI +WVLTAA Sbjct: 33 LEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAA 91 Query: 434 HCFDGLPLQDVWR-----IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIAL 486 HC P + + G + + ++ S +++I IH Y E + DIAL Sbjct: 92 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 151 Query: 487 IKLQAPLNYTEFQKPICLPSKGDTS---TIYTNCWVTGWGFSKEKGE------IQNILQK 537 +KL+ P+ ++++ P+CLP + + VTGWG KE ++LQ Sbjct: 152 MKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQV 211 Query: 538 VNIPLVTNEECQKRYQDYKITQRMVCAGY--KEGGK-DACKGDSGGPLVCKH--NGMWRL 592 VN+P+V C+ + +IT M CAGY EG + DAC+GD+GGP V K N W Sbjct: 212 VNLPIVERPVCKDSTR-IRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQ 270 Query: 593 VGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 +GI SWGEGC R + G YT V WI + Sbjct: 271 MGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVID 304 >4H4F-A nrPDB Length = 249 Score = 282 bits (721), Expect = 4e-76, Method: Composition-based stats. Identities = 94/242 (38%), Positives = 134/242 (55%), Gaps = 10/242 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGG ++ WPWQ+SLQ K RH CGG+LI +VLTAAHC +R+ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT---RTYRVAV 57 Query: 450 GILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 G NL + + + F + I +H+ + +DIALIKL + ++ + CLP K Sbjct: 58 GKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD 117 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGYK 567 C+VTGWG G I + LQ+ P+V + C + + +++ + MVCAG Sbjct: 118 SLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 176 Query: 568 EGGKDACKGDSGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILEK 624 +G AC GDSGGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+DWI EK Sbjct: 177 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 236 Query: 625 TQ 626 Q Sbjct: 237 MQ 238 >1FXY-A nrPDB Length = 228 Score = 281 bits (719), Expect = 6e-76, Method: Composition-based stats. Identities = 81/240 (33%), Positives = 128/240 (53%), Gaps = 13/240 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG N GE PWQ L + CGG+++ ++LTAAHC +++ G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEG--FCGGTILSEFYILTAAHCLYQ---AKRFKVRVG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N +++ +I H + + DIA+++L+ P+ + P LP+ Sbjct: 56 DRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA--P 113 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T C ++GWG + G + + LQ ++ P+++ +C+ Y KIT M C G+ EG Sbjct: 114 PATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPG-KITSNMFCVGFLEG 172 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 GKD+C+GDSGGP+VC +L G+ SWG+GCA++ +PGVYTKV Y+ WI ++ Sbjct: 173 GKDSCQGDSGGPVVCNG----QLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 228 >1BRU-P nrPDB Length = 241 Score = 279 bits (713), Expect = 3e-75, Method: Composition-based stats. Identities = 87/245 (35%), Positives = 138/245 (56%), Gaps = 11/245 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTA-QRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGG ++ WPWQVSLQ + RH CGG+L+ WVLTAAHC +R+ Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS---RTYRVVL 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH--DIALIKLQAPLNYTEFQKPICLPSK 507 G +LS + ++ ++++HQ++ ++ ++ DIAL+KL +P++ T+ + CLP+ Sbjct: 58 GRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAA 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGY 566 G C+VTGWG + G +ILQ+ + +V C K + + M+CAG Sbjct: 118 GTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAG- 176 Query: 567 KEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWGE--GCARREQPGVYTKVAEYMDWILE 623 +G +C GDSGGPL C+ NG W++ GI S+G GC +P V+T+V+ Y+DWI Sbjct: 177 GDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINS 236 Query: 624 KTQSS 628 ++ Sbjct: 237 VIANN 241 >3NXP-A nrPDB Length = 424 Score = 279 bits (713), Expect = 3e-75, Method: Composition-based stats. Identities = 97/274 (35%), Positives = 138/274 (50%), Gaps = 23/274 (8%) Query: 374 LCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAA 433 L + + + + RIV G+++ G PWQV L K + Q LCG SLI +WVLTAA Sbjct: 149 LEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAA 207 Query: 434 HCFDGLPLQDVWR-----IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIAL 486 HC P + + G + + ++ S +++I IH Y E + DIAL Sbjct: 208 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 267 Query: 487 IKLQAPLNYTEFQKPICLPSKGDTS---TIYTNCWVTGWGFSKEKGE------IQNILQK 537 +KL+ P+ ++++ P+CLP + + VTGWG KE ++LQ Sbjct: 268 MKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQV 327 Query: 538 VNIPLVTNEECQKRYQDYKITQRMVCAGY--KEGGK-DACKGDSGGPLVCKH--NGMWRL 592 VN+P+V C+ + +IT M CAGY EG + DAC+GDSGGP V K N W Sbjct: 328 VNLPIVERPVCKDSTR-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQ 386 Query: 593 VGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 +GI SWGEGC R + G YT V WI + Sbjct: 387 MGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVID 420 >1A0J-A nrPDB Length = 223 Score = 279 bits (713), Expect = 3e-75, Method: Composition-based stats. Identities = 87/239 (36%), Positives = 128/239 (53%), Gaps = 17/239 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG +Q SLQ + H CGGSLI WV++AAHC+ + ++ G Sbjct: 1 IVGGYECRKNSASYQASLQ----SGYHFCGGSLISSTWVVSAAHCY-----KSRIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N++ F ++I+H +Y ++DI LIKL P + + + LPS Sbjct: 52 EHNIAVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPS--SC 109 Query: 511 STIYTNCWVTGWGFSK-EKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 ++ T C V+GWG + L+ +++P++++ C Y +IT M CAG+ EG Sbjct: 110 ASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPG-QITSNMFCAGFMEG 168 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 GKD+C+GDSGGP+VC +L G+ SWG GCA+R +PGVYTKV Y WI S+ Sbjct: 169 GKDSCQGDSGGPVVCNG----QLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1MKW-K nrPDB Length = 308 Score = 278 bits (712), Expect = 4e-75, Method: Composition-based stats. Identities = 96/273 (35%), Positives = 133/273 (48%), Gaps = 23/273 (8%) Query: 376 NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 435 + + + + RIV G ++ G PWQV L K + Q LCG SLI +WVLTAAHC Sbjct: 35 DQTEKELFESYIEGRIVEGQDAEVGLSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHC 93 Query: 436 FDGLPLQDVWRI-----YSGILNLSDITKD-TPFSQIKEIIIHQNYKV-SEGNHDIALIK 488 P + + G + + + S + +I IH Y + DIAL+K Sbjct: 94 LLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLK 153 Query: 489 LQAPLNYTEFQKPICLPSKGDTSTI---YTNCWVTGWGFSKEKGEI------QNILQKVN 539 L+ P+ +++ P+CLP K + + VTGWG +E ++LQ VN Sbjct: 154 LKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVN 213 Query: 540 IPLVTNEECQKRYQDYKITQRMVCAGYKEG---GKDACKGDSGGPLVCK--HNGMWRLVG 594 +PLV C+ + +IT M CAGYK G DAC+GDSGGP V K +N W +G Sbjct: 214 LPLVERPVCKASTR-IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMG 272 Query: 595 ITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 I SWGEGC R + G YT V WI + Sbjct: 273 IVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 305 >1PYT-D nrPDB Length = 251 Score = 278 bits (711), Expect = 6e-75, Method: Composition-based stats. Identities = 92/247 (37%), Positives = 131/247 (53%), Gaps = 9/247 (3%) Query: 385 TKTSTRIVGGTNSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 443 S R+VGG ++ WPWQ+SLQ + RH CGG+LI VLTAAHC Sbjct: 8 PNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTL--- 64 Query: 444 VWRIYSGILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 +R+ G NL + + + + I +H+ + +DIALIKL + + + Sbjct: 65 TYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVA 124 Query: 503 CLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRM 561 CLPS+G C+VTGWG G I LQ+ P+V C Q+ + + + M Sbjct: 125 CLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETM 184 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG--CARREQPGVYTKVAEYMD 619 VCAG +G AC GDSGGPL C+ +G W + GI S+G G C ++P V+T+V+ Y+D Sbjct: 185 VCAG-GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYID 243 Query: 620 WILEKTQ 626 WI +K Q Sbjct: 244 WINQKLQ 250 >4Z6A-H nrPDB Length = 249 Score = 275 bits (703), Expect = 4e-74, Method: Composition-based stats. Identities = 95/241 (39%), Positives = 133/241 (55%), Gaps = 7/241 (2%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG GE PWQV L V LCGG+LI WV++AAHCFD + G Sbjct: 1 IVGGKVCPKGECPWQVLLLVN---GAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK--- 507 +LS+ D ++ ++II Y NHDIAL++L P+ T+ P+CLP + Sbjct: 58 EHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFS 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 T V+GWG ++G L +N+P + ++C+ Y KIT+ M CAGY Sbjct: 118 ERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPG-KITEYMFCAGYS 176 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +G KD+CKGDSGGP + G W L GI SWG+GCA GVYT+V++Y++W+ + +S Sbjct: 177 DGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRS 236 Query: 628 S 628 Sbjct: 237 E 237 >1KIG-H nrPDB Length = 241 Score = 275 bits (703), Expect = 4e-74, Method: Composition-based stats. Identities = 82/247 (33%), Positives = 129/247 (52%), Gaps = 9/247 (3%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + + GE PWQ L + CGG+++ +VLTAAHC + + G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG--FCGGTILNEFYVLTAAHCL---HQAKRFTVRVG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG-D 509 N + +++ + H + + DIA+++L+ P+ + P CLP K Sbjct: 56 DRNTEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWA 115 Query: 510 TSTIYT--NCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 +T+ T V+G+G + EKG + + L+ + +P V C+ + IT M CAGY Sbjct: 116 EATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLS-SSFTITPNMFCAGYD 174 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +DAC+GDSGGP V + + + GI SWGEGCAR+ + GVYTKV+ ++ WI + ++ Sbjct: 175 TQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKA 234 Query: 628 SDGKAQM 634 G A Sbjct: 235 RAGAAGS 241 >4KKD-A nrPDB Length = 433 Score = 274 bits (702), Expect = 6e-74, Method: Composition-based stats. Identities = 92/301 (30%), Positives = 143/301 (47%), Gaps = 35/301 (11%) Query: 369 GYSLRLC--NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQ----RHLCGGS 422 G SL C G S RI+GG N+ G +PWQ + V+ T++ + G+ Sbjct: 131 GRSLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGA 190 Query: 423 LIGHQWVLTAAHCFDGLPL--------QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQN 474 L+ W+LTAAH ++ +Y G+ ++ D + S +++H + Sbjct: 191 LLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHPD 249 Query: 475 YKVSEGNHDIALIKLQAPLNYTEFQKPICLPS-KGDTSTIYTNCWVTGWGFSKEK----- 528 + + NHDIAL++LQ P+ P+CLP + + + V GWG S Sbjct: 250 FNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDE 309 Query: 529 ------GEIQNILQKVNIPLVTNEECQKRY----QDYKITQRMVCAGYKEGGKDACKGDS 578 + ++LQ V +P+V + EC+ Y +Y +T+ M CAGY EGGKD C GDS Sbjct: 310 IISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDS 369 Query: 579 GGPLVCKHN--GMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQM 634 G V + W + G+ SWG E C ++ GVYTKV+ Y+DW+ E+ + Sbjct: 370 GEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEP 429 Query: 635 Q 635 Q Sbjct: 430 Q 430 >2OQ5-A nrPDB Length = 232 Score = 273 bits (699), Expect = 1e-73, Method: Composition-based stats. Identities = 94/237 (39%), Positives = 126/237 (53%), Gaps = 9/237 (3%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGT GEWPWQ SLQ H CG +LI W+++AAHCF W G Sbjct: 1 IVGGTEVEEGEWPWQASLQWD---GSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + I ++ II+H+ YK ++DI+L +L +P+ YT +CLP Sbjct: 58 VT----IKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYE 113 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVCAGYKEG 569 +VTG+G K G QN L++ + L+ C + + + IT RM+CAG EG Sbjct: 114 FQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEG 173 Query: 570 GKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 DAC+GDSGGPLV +W L GI SWG+ CA+ +PGVYT+V DWI KT Sbjct: 174 KTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKT 230 >1YC0-A nrPDB Length = 283 Score = 273 bits (697), Expect = 2e-73, Method: Composition-based stats. Identities = 92/257 (35%), Positives = 135/257 (52%), Gaps = 11/257 (4%) Query: 377 TGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF 436 G T RI+GG++S G PW ++ + + C GSL+ WV++AAHCF Sbjct: 22 CGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCF 77 Query: 437 DGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSE-GNHDIALIKLQAP--- 492 P +D + G + T T I++ I + Y V +HD+ LI+L+ Sbjct: 78 SHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDR 137 Query: 493 -LNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQ- 549 ++F +PICLP G T C + GWG E + L++ +PLV + +C Sbjct: 138 CATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSS 197 Query: 550 KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG 609 I+ M+CAGY + DAC+GDSGGPL C+ NG+ L GI SWG+GC R +PG Sbjct: 198 PEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPG 257 Query: 610 VYTKVAEYMDWILEKTQ 626 VYT+VA Y+DWI ++ + Sbjct: 258 VYTRVANYVDWINDRIR 274 >4NZQ-A nrPDB Length = 557 Score = 273 bits (697), Expect = 2e-73, Method: Composition-based stats. Identities = 97/274 (35%), Positives = 138/274 (50%), Gaps = 23/274 (8%) Query: 374 LCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAA 433 L + + + + RIV G+++ G PWQV L K + Q LCG SLI +WVLTAA Sbjct: 282 LEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAA 340 Query: 434 HCFDGLPLQDVWR-----IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIAL 486 HC P + + G + + ++ S +++I IH Y E + DIAL Sbjct: 341 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 400 Query: 487 IKLQAPLNYTEFQKPICLPSKGDTS---TIYTNCWVTGWGFSKEKGE------IQNILQK 537 +KL+ P+ ++++ P+CLP + + VTGWG KE ++LQ Sbjct: 401 MKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQV 460 Query: 538 VNIPLVTNEECQKRYQDYKITQRMVCAGY--KEGGK-DACKGDSGGPLVCKH--NGMWRL 592 VN+P+V C+ + +IT M CAGY EG + DAC+GDSGGP V K N W Sbjct: 461 VNLPIVERPVCKDSTR-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQ 519 Query: 593 VGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 +GI SWGEGC R + G YT V WI + Sbjct: 520 MGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVID 553 >2OCV-B nrPDB Length = 259 Score = 272 bits (695), Expect = 3e-73, Method: Composition-based stats. Identities = 91/257 (35%), Positives = 128/257 (49%), Gaps = 23/257 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR---- 446 IV G ++ G PWQV L K + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 447 -IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 + G + + ++ S +++I +H Y E + DIAL+KL+ P+ ++++ P+C Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 504 LPSKGDT---STIYTNCWVTGWGFSKEKGEI------QNILQKVNIPLVTNEECQKRYQD 554 LP K VTGWG +E ++LQ VN+P+V C+ + Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTR- 178 Query: 555 YKITQRMVCAGY---KEGGKDACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQPG 609 +IT M CAG+ DAC+GDSGGP V K N W +GI SWGEGC R+ + G Sbjct: 179 IRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYG 238 Query: 610 VYTKVAEYMDWILEKTQ 626 YT V WI + Sbjct: 239 FYTHVFRLKAWIQKVID 255 >1ETT-H nrPDB Length = 259 Score = 271 bits (693), Expect = 6e-73, Method: Composition-based stats. Identities = 95/258 (36%), Positives = 128/258 (49%), Gaps = 23/258 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI--- 447 IV G ++ G PWQV L K + Q LCG SLI +WVLTAAHC P + + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 448 --YSGILNLSDITKD-TPFSQIKEIIIHQNYKV-SEGNHDIALIKLQAPLNYTEFQKPIC 503 G + + + S + +I IH Y + DIAL+KL+ P+ +++ P+C Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 504 LPSKGDTSTI---YTNCWVTGWGFSKEKGEI------QNILQKVNIPLVTNEECQKRYQD 554 LP K + + VTGWG +E ++LQ VN+PLV C+ + Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR- 178 Query: 555 YKITQRMVCAGYKEG---GKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARREQPG 609 +IT M CAGYK G DAC+GDSGGP V K +N W +GI SWGEGC R + G Sbjct: 179 IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG 238 Query: 610 VYTKVAEYMDWILEKTQS 627 YT V WI + Sbjct: 239 FYTHVFRLKKWIQKVIDR 256 >1EUF-A nrPDB Length = 227 Score = 271 bits (693), Expect = 7e-73, Method: Composition-based stats. Identities = 69/237 (29%), Positives = 108/237 (45%), Gaps = 12/237 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ L K + + H+CGG L+ +VLTAAHC + G Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSS-----INVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + ++ I H +Y +DI L+KL + T+ PI LP Sbjct: 56 AHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAE 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C V GWG + LQ+V++ + + E+C R+++Y I +CAG Sbjct: 116 VKPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNY-IPFTQICAGDPSKR 174 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 K++ GDSGGPLVC GI S+G P VYT+++ ++ WI + Sbjct: 175 KNSFSGDSGGPLVCNG----VAQGIVSYGRNDGT--TPDVYTRISSFLSWIHSTMRR 225 >1FI8-A nrPDB Length = 228 Score = 271 bits (692), Expect = 8e-73, Method: Composition-based stats. Identities = 69/239 (28%), Positives = 114/239 (47%), Gaps = 12/239 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG + P+ LQ+ + CGG LI +VLTAAHC ++ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-----SGSKIQVTL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N+ + K + +II H Y ++DI L+KL++ + KP+ LP + Sbjct: 56 GAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNV 115 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 C+V GWG G+ + LQ+V + + +++C+ ++Y +CAG + Sbjct: 116 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKI 175 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 + + +GDSGGPLVCK GI S+G+ P +TKV+ ++ WI + + S Sbjct: 176 KRASFRGDSGGPLVCKK----VAAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKTMKKS 228 >2CGA-A nrPDB Length = 245 Score = 270 bits (691), Expect = 1e-72, Method: Composition-based stats. Identities = 94/254 (37%), Positives = 135/254 (53%), Gaps = 11/254 (4%) Query: 377 TGDNSVCTTKTS-TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 435 G ++ + +RIV G + G WPWQVSLQ K H CGGSLI WV+TAAHC Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDK--TGFHFCGGSLINENWVVTAAHC 58 Query: 436 FDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNY 495 G+ DV + +G + ++ +I ++ + Y N+DI L+KL ++ Sbjct: 59 --GVTTSDV--VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASF 114 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSK-EKGEIQNILQKVNIPLVTNEECQKRYQD 554 ++ +CLPS D T C TGWG ++ + LQ+ ++PL++N C+K Y Sbjct: 115 SQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKK-YWG 173 Query: 555 YKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKV 614 KI M+CAG G +C GDSGGPLVCK NG W LVGI SWG PGVY +V Sbjct: 174 TKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARV 231 Query: 615 AEYMDWILEKTQSS 628 ++W+ + ++ Sbjct: 232 TALVNWVQQTLAAN 245 >1C5M-D nrPDB Length = 255 Score = 269 bits (689), Expect = 2e-72, Method: Composition-based stats. Identities = 83/251 (33%), Positives = 128/251 (50%), Gaps = 10/251 (3%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG GE PWQ L + CGG+++ ++LTAAHC +++ G Sbjct: 1 IVGGQECKDGECPWQALLINEENEG--FCGGTILSEFYILTAAHCLYQ---AKRFKVRVG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG-D 509 N +++ +I H + + DIA+++L+ P+ + P CLP + Sbjct: 56 DRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWA 115 Query: 510 TSTIYT--NCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 ST+ T V+G+G + EKG L+ + +P V C+ + ITQ M CAGY Sbjct: 116 ESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLS-SSFIITQNMFCAGYD 174 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +DAC+GDSGGP V + + + GI SWGEGCAR+ + G+YTKV ++ WI ++ Sbjct: 175 TKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 234 Query: 628 SD-GKAQMQSP 637 KA+ +P Sbjct: 235 RGLPKAKSHAP 245 >1SC8-U nrPDB Length = 262 Score = 269 bits (689), Expect = 2e-72, Method: Composition-based stats. Identities = 80/254 (31%), Positives = 138/254 (54%), Gaps = 10/254 (3%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQR--HLCGGSLIGHQWVLTAAHCFDGLPL 441 T + +I+GG ++ PW ++ + ++CGGSLI WV++A HCF P Sbjct: 9 TLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPK 68 Query: 442 QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAP----LNY 495 ++ + +Y G L+ T+ +++ +I+H++Y ++DIAL+K+++ Sbjct: 69 KEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQP 128 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQK-RYQ 553 + + I LPS + T+C +TG+G L+ + L+++ ECQ+ Y Sbjct: 129 SRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYY 188 Query: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613 ++T +M+CA + D+C+GDSGGPLVC G L GI SWG GCA +++PGVYT+ Sbjct: 189 GSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTR 248 Query: 614 VAEYMDWILEKTQS 627 V+ ++ WI T+ Sbjct: 249 VSHFLPWIRSHTKE 262 >1FIZ-A nrPDB Length = 263 Score = 269 bits (687), Expect = 3e-72, Method: Composition-based stats. Identities = 102/251 (40%), Positives = 133/251 (52%), Gaps = 13/251 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQ---VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 +VGG ++ G WPW VSLQ + H CGG L+ WVLTAAHCF WR+ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 448 YSGILNL-----SDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 G + + ++EIIIH+ Y +DIALIK+ P+ F P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 503 CLPS-KGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQK-RYQDYKITQ 559 CLP K CWVTGWG+ KEKG LQ+ + L+ E C R+ + +I Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHN--GMWRLVGITSWGEGCARREQPGVYTKVAEY 617 VCAGY G D C+GDSGGPL+C+ + +VGITSWG GCAR ++PGVYT Y Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPY 240 Query: 618 MDWILEKTQSS 628 ++WI K S+ Sbjct: 241 LNWIASKIGSN 251 >1SGF-G nrPDB Length = 237 Score = 268 bits (685), Expect = 6e-72, Method: Composition-based stats. Identities = 87/251 (34%), Positives = 132/251 (52%), Gaps = 28/251 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PW V++ ++LCGG L+ WVLTAAHC+D D ++++ G Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYT---QYLCGGVLLDPNWVLTAAHCYD-----DNYKVWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYTEFQ 499 NL + + I H + +S + ++D+ L++L P + T+ Sbjct: 53 KNNLFKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT 558 KPI LP++ + + C +GWG + K + + L VN+ L+ NE+C K + + K+T Sbjct: 113 KPITLPTE--EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIE-KVT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEY 617 M+CAG +GGKD CKGDSGGPL+C L GITSWG C + PGVYTK+ ++ Sbjct: 170 DAMLCAGEMDGGKDTCKGDSGGPLICDG----VLQGITSWGHTPCGEPDMPGVYTKLNKF 225 Query: 618 MDWILEKTQSS 628 WI + + Sbjct: 226 TSWIKDTMAKN 236 >1BDA-A nrPDB Length = 265 Score = 267 bits (683), Expect = 1e-71, Method: Composition-based stats. Identities = 78/257 (30%), Positives = 130/257 (50%), Gaps = 15/257 (5%) Query: 385 TKTSTRIVGGTNSSWGEWPWQVSL---QVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPL 441 ++ RI GG + PWQ ++ + +R LCGG LI W+L+AAHCF Sbjct: 8 SQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFP 67 Query: 442 QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAP----LNYTE 497 + G ++ ++++ I+H+ + ++DIAL++L++ + Sbjct: 68 PHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESS 127 Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQ-DY 555 + +CLP +T C ++G+G + L++ ++ L + C ++ + Sbjct: 128 VVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNR 187 Query: 556 KITQRMVCAGYKEGGK------DACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPG 609 +T M+CAG G DAC+GDSGGPLVC ++G LVGI SWG GC +++ PG Sbjct: 188 TVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPG 247 Query: 610 VYTKVAEYMDWILEKTQ 626 VYTKV Y+DWI + + Sbjct: 248 VYTKVTNYLDWIRDNMR 264 >4IW4-E nrPDB Length = 279 Score = 267 bits (682), Expect = 1e-71, Method: Composition-based stats. Identities = 86/277 (31%), Positives = 137/277 (49%), Gaps = 33/277 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQ----RHLCGGSLIGHQWVLTAAHCFDGLPL----- 441 I+GG N+ G +PWQ + V+ T++ + G+L+ W+LTAAH Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 442 ---QDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEF 498 ++ +Y G+ ++ D + S +++H ++ + NHDIAL++LQ P+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAV-NSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 499 QKPICLPS-KGDTSTIYTNCWVTGWGFSKEK-----------GEIQNILQKVNIPLVTNE 546 P+CLP + + + V GWG S + ++LQ V +P+V + Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 547 ECQKRY----QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHN--GMWRLVGITSWG- 599 EC+ Y +Y +T+ M CAGY EGGKD C GDSGG V + W + G+ SWG Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 600 -EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQ 635 E C ++ GVYTKV+ Y+DW+ E+ + Q Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEPQ 276 >1VR1-H nrPDB Length = 261 Score = 266 bits (680), Expect = 2e-71, Method: Composition-based stats. Identities = 93/260 (35%), Positives = 131/260 (50%), Gaps = 25/260 (9%) Query: 391 IVGGTNSSWGEWPWQVSL---QVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR- 446 IV G+++ G PWQV L + +R LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 447 ----IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQK 500 + G + + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 501 PICLPSKGDTS---TIYTNCWVTGWGFSKEKGE------IQNILQKVNIPLVTNEECQKR 551 P+CLP + + VTGWG KE ++LQ VN+P+V C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 552 YQDYKITQRMVCAGY--KEGGK-DACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARRE 606 + +IT M CA Y EG + DAC+GDSGGP V K N W +GI SWGEGC R Sbjct: 181 TR-IRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 239 Query: 607 QPGVYTKVAEYMDWILEKTQ 626 + G YT V WI + Sbjct: 240 KYGFYTHVFRLKKWIQKVID 259 >2V35-A nrPDB Length = 240 Score = 266 bits (680), Expect = 2e-71, Method: Composition-based stats. Identities = 80/244 (32%), Positives = 129/244 (52%), Gaps = 10/244 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKL-TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGGT + WP Q+SLQ + ++ H CGG+LI WV+TAAHC D + +R+ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVD---RELTFRVVV 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEG--NHDIALIKLQAPLNYTEFQKPICLPSK 507 G NL+ + +++I++H + + +DIAL++L + + + LP Sbjct: 58 GEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRA 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGY 566 G + C++TGWG ++ G++ LQ+ +P V C Y + MVCAG Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAG- 176 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE--GCARREQPGVYTKVAEYMDWILEK 624 +G + C+GDSGGPL C NG + + G+TS+ GC +P V+T+V+ Y+ WI Sbjct: 177 GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNV 236 Query: 625 TQSS 628 S+ Sbjct: 237 IASN 240 >2EEK-A nrPDB Length = 220 Score = 265 bits (678), Expect = 3e-71, Method: Composition-based stats. Identities = 86/235 (36%), Positives = 123/235 (52%), Gaps = 16/235 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + QVSL + H CGGSL+ WV++AAHC+ + V R+ G Sbjct: 1 IVGGYECTKHSQAHQVSL----NSGYHFCGGSLVSKDWVVSAAHCY-----KSVLRVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 ++ + +I H NY N+DI LIKL P ++ + LP++ Sbjct: 52 EHHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTE--C 109 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 + T C V+GWG + + LQ +++P++++ +C Y ITQ M CAGY EGG Sbjct: 110 AADATMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGM-ITQSMFCAGYLEGG 168 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 KD+C+GDSGGP+VC L G+ SWG GCA R+ PGVY KV W+ + Sbjct: 169 KDSCQGDSGGPVVCNG----VLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >4NFE-A nrPDB Length = 237 Score = 265 bits (677), Expect = 5e-71, Method: Composition-based stats. Identities = 89/251 (35%), Positives = 128/251 (50%), Gaps = 28/251 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQV++ A CGG L+ QWVLTAAHC + +++ G Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAH---CGGVLVHPQWVLTAAHCL-----KKNSQVWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYTEFQ 499 NL + + H Y +S + +HD+ L++L P T+ Sbjct: 53 RHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI-QNILQKVNIPLVTNEECQKRYQDYKIT 558 K + LP++ + T C+ +GWG + + + LQ V++ L++N+ C + Y + K+T Sbjct: 113 KVLGLPTQ--EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE-KVT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEY 617 + M+CAG GGKD C GDSGGPLVC L GITSWG E CA E+P VYTKV Y Sbjct: 170 EFMLCAGLWTGGKDTCGGDSGGPLVCNG----VLQGITSWGPEPCALPEKPAVYTKVVHY 225 Query: 618 MDWILEKTQSS 628 WI + ++ Sbjct: 226 RKWIKDTIAAN 236 >3F6U-H nrPDB Length = 240 Score = 265 bits (677), Expect = 5e-71, Method: Composition-based stats. Identities = 88/245 (35%), Positives = 126/245 (51%), Gaps = 15/245 (6%) Query: 392 VGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGI 451 + G + G+ PWQV L + ++ CG LI WVLTAAHC D + G Sbjct: 2 IDGKMTRRGDSPWQVVLL--DSKKKLACGAVLIHPSWVLTAAHCMDESKK---LLVRLGE 56 Query: 452 LNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG--- 508 +L K IKE+ +H NY S ++DIAL+ L P ++ PICLP G Sbjct: 57 YDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAE 116 Query: 509 -DTSTIYTNCWVTGWGFSKEKGEIQN-----ILQKVNIPLVTNEECQKRYQDYKITQRMV 562 + + VTGWG+ + + +L + IP+V + EC + + +++ M+ Sbjct: 117 RELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNM-VSENML 175 Query: 563 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWIL 622 CAG +DAC+GDSGGP+V +G W LVG+ SWGEGC GVYTKV+ Y+DWI Sbjct: 176 CAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIH 235 Query: 623 EKTQS 627 + Sbjct: 236 GHIRD 240 >2R0L-A nrPDB Length = 248 Score = 264 bits (675), Expect = 8e-71, Method: Composition-based stats. Identities = 89/243 (36%), Positives = 132/243 (54%), Gaps = 11/243 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG++S G PW ++ + + C GSL+ WV++AAHCF P +D + G Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE-GNHDIALIKLQAP----LNYTEFQKPICLP 505 + T T I++ I + Y V +HD+ LI+L+ ++F +PICLP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 506 SKGDTSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQ-KRYQDYKITQRMVC 563 G T C + GWG E + L++ +PLV + +C I+ M+C Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623 AGY + DAC+GDSGGPL C+ NG+ L GI SWG+GC R +PGVYT+VA Y+DWI + Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 236 Query: 624 KTQ 626 + + Sbjct: 237 RIR 239 >2TLD-E nrPDB Length = 220 Score = 264 bits (675), Expect = 9e-71, Method: Composition-based stats. Identities = 87/239 (36%), Positives = 132/239 (55%), Gaps = 20/239 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG P+QVSL + H CGGSLI QWV++AAHC+ + ++ G Sbjct: 1 IVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCY-----KSGIQVRLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N++ + + F + I+H +Y + N+DI LIKL++ + I LP+ Sbjct: 52 EDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SC 109 Query: 511 STIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 ++ T C ++GWG +K G ++L+ + P++++ C+ Y +IT M CAG + Sbjct: 110 ASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPG-QITSNMFCAGLE-- 166 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 G D+C+GDSGGP+VC L GI SWG GCA+ +PGVYTKV Y+ WI + S+ Sbjct: 167 GGDSCQGDSGGPVVCSGK----LQGIVSWGSGCAK-NKPGVYTKVCNYVSWIKQTIASN 220 >1FIW-A nrPDB Length = 290 Score = 263 bits (671), Expect = 2e-70, Method: Composition-based stats. Identities = 99/251 (39%), Positives = 137/251 (54%), Gaps = 13/251 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQ---VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 I+GG +++ G WPW VSLQ + H+CGGSL+ QW+LTAAHCF WR+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 448 YSGILNLS-----DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 G + + +++IIIH+ Y S +DIAL+K+ P+ F P Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 503 CLPS-KGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQK-RYQDYKITQ 559 CLP + + CWV GWGF +E +LQ+ + L+ C R+ + +I Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQPGVYTKVAEY 617 VCAGY EG D C+GDSGGPL+CK + +VGITSWG GCAR ++PGVYT Y Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWSY 240 Query: 618 MDWILEKTQSS 628 ++WI K S+ Sbjct: 241 LNWIASKIGST 251 >1IAU-A nrPDB Length = 227 Score = 261 bits (668), Expect = 5e-70, Method: Composition-based stats. Identities = 68/237 (28%), Positives = 103/237 (43%), Gaps = 11/237 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ L + CGG LI +VLTAAHC + G Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSINVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + F +K I H Y ++DI L++L+ T +P+ LPS Sbjct: 56 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C V GWG + G+ + LQ+V + + + +C+ + Y + +C G E Sbjct: 116 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 175 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 K + KGDSGGPLVC GI S+G P TKV+ ++ WI + + Sbjct: 176 KTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMKR 226 >1ELT-A nrPDB Length = 236 Score = 260 bits (665), Expect = 1e-69, Method: Composition-based stats. Identities = 79/241 (32%), Positives = 119/241 (49%), Gaps = 11/241 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKL-TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 +VGG + WPWQ+SLQ K ++ H CGGSLI WV+TAAHC D WR+ Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDS---ARTWRVVL 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAPLNYTEFQKPICLPSK 507 G NL+ + + IH + + G +DIAL++L + + LP Sbjct: 58 GEHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPS 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGY 566 C++TGWG + G + + L++ +P V + C + + MVCAG Sbjct: 118 NQILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG 177 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEK 624 G C GDSGGPL C+ NG + + G+TS+ GC ++P V+T+V+ Y+ W+ Sbjct: 178 --GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGI 235 Query: 625 T 625 Sbjct: 236 M 236 >1A5I-A nrPDB Length = 265 Score = 259 bits (662), Expect = 3e-69, Method: Composition-based stats. Identities = 81/248 (32%), Positives = 128/248 (51%), Gaps = 15/248 (6%) Query: 393 GGTNSSWGEWPWQVSL---QVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 GG + PWQ ++ + + +R LCGG LI WVLTAAHCF L D ++ Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAP----LNYTEFQKPICLP 505 G ++ ++K+ I+H+ + N+DIAL++L++ ++ + ICLP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQ-DYKITQRMVC 563 +T C ++G+G K L++ ++ L + C ++ + +T M+C Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 564 AGYKEGGK------DACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEY 617 AG G+ DAC+GDSGGPLVC ++ L+GI SWG GC ++ PGVYTKV Y Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNY 255 Query: 618 MDWILEKT 625 + WI + Sbjct: 256 LGWIRDNM 263 >5LHN-A nrPDB Length = 247 Score = 258 bits (660), Expect = 4e-69, Method: Composition-based stats. Identities = 83/246 (33%), Positives = 129/246 (52%), Gaps = 11/246 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVK---LTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 IVGG + PW ++ K + CGGSLI WV +AAHCF LP ++ + + Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAP----LNYTEFQKP 501 Y G S +++++I+H+ Y+ ++DIAL+K++ + + Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 502 ICLPSKGDTSTIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEEC-QKRYQDYKITQ 559 I LP + + ++C +TG+G E L+ + LV++E+C Q Y +I Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619 +M+CA E D+CKGDSGGPL+C G L GI SWG GCA + +PGVYT+V+ ++D Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLD 240 Query: 620 WILEKT 625 WI Sbjct: 241 WIQSHI 246 >1SPJ-A nrPDB Length = 238 Score = 257 bits (656), Expect = 1e-68, Method: Composition-based stats. Identities = 85/253 (33%), Positives = 124/253 (49%), Gaps = 29/253 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQ +L T Q CGG L+ QWVLTAAHC D ++++ G Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQ---CGGILVHRQWVLTAAHCIS-----DNYQLWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPL-NYTEF 498 NL D F + E H + +S + +HD+ L++L P T+ Sbjct: 53 RHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDA 112 Query: 499 QKPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKI 557 K + LP++ + + C +GWG E + LQ V++ ++ N+EC+K + K+ Sbjct: 113 VKVVELPTE--EPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQ-KV 169 Query: 558 TQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAE 616 T M+C G+ EGGKD C GDSGGPL+C L G+TSWG C +P V +V Sbjct: 170 TDFMLCVGHLEGGKDTCVGDSGGPLMCDG----VLQGVTSWGYVPCGTPNKPSVAVRVLS 225 Query: 617 YMDWILEKTQSSD 629 Y+ WI + + Sbjct: 226 YVKWIEDTIAENS 238 >5FCR-A nrPDB Length = 234 Score = 256 bits (653), Expect = 3e-68, Method: Composition-based stats. Identities = 73/240 (30%), Positives = 118/240 (49%), Gaps = 11/240 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG ++ P+ S+QV T H+CGG+L+ QWVL+AAHC DG+ D ++ G Sbjct: 1 ILGGQEAAAHARPYMASVQVNGT---HVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +LS + ++ ++ H + D+ L KL + +P+ L + Sbjct: 58 AHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKE 117 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-KRYQDYKITQRMVCAGYKEG 569 T C V GWG G ++L ++ + ++ C + Y D +T M+CA + Sbjct: 118 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESN 175 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWILEKTQSS 628 +D C+GDSG PLVC + G+ +WG C ++PGVYT+V+ Y WI T + Sbjct: 176 RRDTCRGDSGSPLVCGD----AVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >6QHB-A nrPDB Length = 223 Score = 255 bits (652), Expect = 3e-68, Method: Composition-based stats. Identities = 89/237 (37%), Positives = 128/237 (54%), Gaps = 17/237 (7%) Query: 392 VGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGI 451 V G P+Q +L T+ LCGG LI WVLTAAHC + +++ G Sbjct: 2 VHGGPCDKTSHPYQAALY---TSGHLLCGGVLIHPLWVLTAAHC-----KKPNLQVFLGK 53 Query: 452 LNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTS 511 NL S + +IH +Y + + DI L++L P +E +P LP + D S Sbjct: 54 HNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCS 111 Query: 512 TIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGK 571 T+C + GWG + + G+ + +Q I LV+ EEC+ Y +ITQ M+CAG ++ GK Sbjct: 112 AQTTSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAYPG-QITQNMLCAGDEKYGK 169 Query: 572 DACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQS 627 D+C+GDSGGPLVC + L G+ SWG C +E+PGVYT V Y +WI + Q+ Sbjct: 170 DSCQGDSGGPLVCGDH----LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 222 >5MS3-A nrPDB Length = 228 Score = 254 bits (648), Expect = 1e-67, Method: Composition-based stats. Identities = 82/242 (33%), Positives = 118/242 (48%), Gaps = 21/242 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG PWQ +L Q+ LCGG L+G WVLTAAHC + + + G Sbjct: 1 VLGGHECQPHSQPWQAAL---FQGQQLLCGGVLVGGNWVLTAAHC-----KKPKYTVRLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE---GNHDIALIKLQAPLNYTEFQKPICLPSK 507 +L + + + I H Y S+ NHD+ L++L+ + KPI L Sbjct: 53 DHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 508 GDTSTIYTNCWVTGWGF-SKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 C V+GWG + + + L + + ++C+ Y +IT MVCAG Sbjct: 113 CT--QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPG-QITDGMVCAGS 169 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKT 625 +G D C+GDSGGPLVC L GITSWG + C R ++PGVYT + Y+DWI + Sbjct: 170 SKGA-DTCQGDSGGPLVCDG----ALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 Query: 626 QS 627 S Sbjct: 225 GS 226 >3G01-A nrPDB Length = 227 Score = 253 bits (646), Expect = 2e-67, Method: Composition-based stats. Identities = 64/237 (27%), Positives = 107/237 (45%), Gaps = 12/237 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG S P+ + K+ ++ CGG L+ ++VLTAAHC + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC-----KGRSMTVTL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N+ + + + I H +Y + ++DI L+KL T +P+ LP + Sbjct: 56 GAHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNA 115 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 C+V GWG GE L +V + + ++ C+ ++Q +C G + Sbjct: 116 HVKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKI 175 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 + +GDSGGPLVCK GI S+G+ P V+T+V ++ WI + + Sbjct: 176 KGASFRGDSGGPLVCKR----AAAGIVSYGQTDGSA--PQVFTRVLSFVSWIKKTMK 226 >1NPM-A nrPDB Length = 225 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 83/241 (34%), Positives = 119/241 (49%), Gaps = 21/241 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G PWQ +L +R +CGG L+G +WVLTAAHC + + + G Sbjct: 1 ILEGRECIPHSQPWQAAL---FQGERLICGGVLVGDRWVLTAAHC-----KKQKYSVRLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYK---VSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 +L + Q+ + I H Y + +HDI LI+LQ N + KP+ L Sbjct: 53 DHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--A 110 Query: 508 GDTSTIYTNCWVTGWGF-SKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566 + C ++GWG + + N L + + + +C++ Y KIT+ MVCAG Sbjct: 111 NLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPG-KITEGMVCAGS 169 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKT 625 G D C+GDSGGPLVC L GITSWG + C + E+PGVYTK+ Y WI + Sbjct: 170 -SNGADTCQGDSGGPLVCDG----MLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 Query: 626 Q 626 Sbjct: 225 D 225 >4XDE-A nrPDB Length = 257 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 87/247 (35%), Positives = 120/247 (48%), Gaps = 14/247 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG + G P+ +L C GSLI WVLTAAHC P + + G Sbjct: 3 VVGGLVALRGAHPYIAALYW----GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLN-----YTEFQKPICLP 505 + + ++ +H+ + HD+AL++LQ + + + +P+ LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 506 SKGDTSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVC 563 S + T C V GWG E E + LQ+ +P ++ E C I M+C Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLC 178 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNG---MWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 AG+ EGG DAC+GDSGGPLVC+ L GI SWG GC R +PGVYT VA Y+ W Sbjct: 179 AGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAW 238 Query: 621 ILEKTQS 627 I E T S Sbjct: 239 IREHTVS 245 >1FDP-A nrPDB Length = 235 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 76/241 (31%), Positives = 114/241 (47%), Gaps = 12/241 (4%) Query: 387 TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 446 RI+GG + P+ S+Q+ HLCGG L+ QWVL+AAHC + V + Sbjct: 4 PRGRILGGREAEAHARPYMASVQLN---GAHLCGGVLVAEQWVLSAAHCLEDAADGKV-Q 59 Query: 447 IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506 + G +LS + + H + + +HD+ L++L +P+ Sbjct: 60 VLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQR 119 Query: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAG 565 T C V GWG G + LQ V +P++ C +R + D IT+R++CA Sbjct: 120 VDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA- 178 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGIT-SWGEGCARREQPGVYTKVAEYMDWILEK 624 + +D+CKGDSGGPLVC L G+ S C R++PG+YT+VA Y WI Sbjct: 179 -ESNRRDSCKGDSGGPLVCGG----VLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSV 233 Query: 625 T 625 Sbjct: 234 L 234 >3QUM-P nrPDB Length = 237 Score = 252 bits (643), Expect = 4e-67, Method: Composition-based stats. Identities = 86/251 (34%), Positives = 123/251 (49%), Gaps = 28/251 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQV + + R +CGG L+ QWVLTAAHC + I G Sbjct: 1 IVGGWECEKHSQPWQVLV---ASRGRAVCGGVLVHPQWVLTAAHCIRNKSV-----ILLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKV-----------SEGNHDIALIKLQAPLNYTEFQ 499 +L Q+ H Y + + +HD+ L++L P T+ Sbjct: 53 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT 558 K + LP++ + T C+ +GWG E+ LQ V++ +++N+ C + + K+T Sbjct: 113 KVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEY 617 + M+CAG GGK C GDSGGPLVC L GITSWG E CA E+P +YTKV Y Sbjct: 170 KFMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVVHY 225 Query: 618 MDWILEKTQSS 628 WI + ++ Sbjct: 226 RKWIKDTIVAN 236 >1FON-A nrPDB Length = 240 Score = 249 bits (637), Expect = 2e-66, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 120/245 (48%), Gaps = 14/245 (5%) Query: 393 GGTNSSWGEWPWQVSLQV-KLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGI 451 G ++ W WQVSLQ K A H CGGSLI WV+TA HC +++ G Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCIS---TSRTYQVVLGE 57 Query: 452 LNLSDITKDTPFSQIK--EIIIHQNYKVSEG--NHDIALIKLQAPLNYTEFQKPICLPSK 507 + S + I ++ +H + + +DIAL+KL + + LP Sbjct: 58 YDRSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPA 117 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGY 566 GD C+++GWG G + + LQ+ +P V E C + + + + MVCAG Sbjct: 118 GDILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGG 177 Query: 567 KEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWGE--GCARREQPGVYTKVAEYMDWILE 623 + C GDSGGPL C +G W++ G+TS+ GC ++P V+T+V+ ++DWI E Sbjct: 178 DT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDE 235 Query: 624 KTQSS 628 S+ Sbjct: 236 TIASN 240 >1AO5-A nrPDB Length = 237 Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 122/251 (48%), Gaps = 28/251 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG N PWQV++ + + H+CGG L+ WVLTAAHC+ D + ++ G Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----VDQYEVWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLNYTEFQ 499 L + + H + +S + + D+ L++L P + T+ Sbjct: 53 KNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT 558 KPI LP+K + C +GWG + + + + LQ V I L+ NE C K Y K+T Sbjct: 113 KPIALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEY 617 M+CAG GGKD C+ DSGGPL+C L G TS+G C + P +YT + ++ Sbjct: 170 DVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKF 225 Query: 618 MDWILEKTQSS 628 WI + + Sbjct: 226 NSWIKDTMMKN 236 >2PSX-A nrPDB Length = 227 Score = 249 bits (635), Expect = 4e-66, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 128/242 (52%), Gaps = 18/242 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G++ PWQ +L ++ + CG L+ QW+LTAAHC + V+R+ G Sbjct: 1 IINGSDCDMHTQPWQAALLLR--PNQLYCGAVLVHPQWLLTAAHC-----RKKVFRVRLG 53 Query: 451 ILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 +LS Q + I H Y ++D+ LIKL + T+ +PI + S Sbjct: 54 HYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH-- 111 Query: 510 TSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 + T C V+GWG +K + +LQ +NI +++ + C+ Y +I M CAG + Sbjct: 112 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP-RQIDDTMFCAGD-K 169 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQS 627 G+D+C+GDSGGP+VC + L G+ SWG+ CAR +PGVYT + ++ WI E Q+ Sbjct: 170 AGRDSCQGDSGGPVVCNGS----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 225 Query: 628 SD 629 + Sbjct: 226 NS 227 >1NN6-A nrPDB Length = 228 Score = 248 bits (633), Expect = 7e-66, Method: Composition-based stats. Identities = 69/241 (28%), Positives = 108/241 (44%), Gaps = 14/241 (5%) Query: 389 TRIVGGTNSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447 I+GGT P+ L+ V CGG LI +VLTAAHC + Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-----AGRSITV 55 Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507 G N+++ ++ + H Y S +HDI L+KL+ + T + PS+ Sbjct: 56 TLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQ 115 Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + C V GWG + + LQ+V + L+ + C ++D+ + +C G Sbjct: 116 FNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQ-LCVGNP 173 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 K A KGDSGGPL+C GI S+G A+ P V+T+++ Y WI + Q+ Sbjct: 174 RKTKSAFKGDSGGPLLCAG----VAQGIVSYGRSDAKP--PAVFTRISHYRPWINQILQA 227 Query: 628 S 628 + Sbjct: 228 N 228 >3TK9-A nrPDB Length = 226 Score = 248 bits (632), Expect = 7e-66, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 105/237 (44%), Gaps = 12/237 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ +Q R CGG L+ +VLTAAHC + G Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC-----QGSSINVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + + F +K I H Y +++I L++L+ +T +P+ LPS Sbjct: 56 AHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQ 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C V GWG+ + LQ+V + + + +C++ + +C G + Sbjct: 116 VKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKT 174 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 + KGDSGGPLVCK GI S+G + PGVY KV+ ++ WI + Sbjct: 175 QTGFKGDSGGPLVCKD----VAQGILSYGN--KKGTPPGVYIKVSHFLPWIKRTMKR 225 >5TO3-B nrPDB Length = 409 Score = 244 bits (624), Expect = 6e-65, Method: Composition-based stats. Identities = 93/257 (36%), Positives = 130/257 (50%), Gaps = 23/257 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR---- 446 IV G+++ G PWQV L K + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 447 -IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 + G + + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ P+C Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 504 LPSKGDTS---TIYTNCWVTGWGFSKEKGE------IQNILQKVNIPLVTNEECQKRYQD 554 LP + + VTGWG KE ++LQ VN+P+V C+ + Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTR- 178 Query: 555 YKITQRMVCAGY--KEGGK-DACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQPG 609 +IT M CAGY EG + DAC+GDSGGP V K N W +GI S G GC R + G Sbjct: 179 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKYG 238 Query: 610 VYTKVAEYMDWILEKTQ 626 YT V WI + Sbjct: 239 FYTHVFRLKKWIQKVID 255 >1Q3X-A nrPDB Length = 328 Score = 244 bits (623), Expect = 9e-65, Method: Composition-based stats. Identities = 94/270 (34%), Positives = 129/270 (47%), Gaps = 27/270 (10%) Query: 371 SLRLCNTGDNSVCTTK---TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQ 427 SL +C VC T RI GG + G++PWQV + TA G+L+ Sbjct: 68 SLPVCEP----VCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTTA-----AGALLYDN 118 Query: 428 WVLTAAH-CFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIA 485 WVLTAAH ++ I G L +S + + IH+ Y G ++DIA Sbjct: 119 WVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWS--EAVFIHEGYTHDAGFDNDIA 176 Query: 486 LIKLQAPLNYTEFQKPICLPSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLV 543 LIKL + PICLP K S + T+ +GWG ++ +G + L V+IP+V Sbjct: 177 LIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIV 235 Query: 544 TNEECQKRY-----QDYKITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGIT 596 +++C Y +T M+CAG + GGKD+C+GDSGG LV W + GI Sbjct: 236 DHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIV 295 Query: 597 SWGE-GCARREQPGVYTKVAEYMDWILEKT 625 SWG C Q GVYTKV Y+ WI Sbjct: 296 SWGSMNCGEAGQYGVYTKVINYIPWIENII 325 >4IGD-A nrPDB Length = 406 Score = 244 bits (622), Expect = 1e-64, Method: Composition-based stats. Identities = 89/276 (32%), Positives = 125/276 (45%), Gaps = 25/276 (9%) Query: 369 GYSLRLC--NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGH 426 G SL C G + K +I G + G PW L + CGGSL+G Sbjct: 133 GRSLPTCLPVCGLPKF-SRKLMAQIFNGRPAQKGTTPWIAMLSHLN--GQPFCGGSLLGS 189 Query: 427 QWVLTAAHCF-------------DGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQ 473 W++TAAHC L ++I G ++ +K +H Sbjct: 190 SWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHP 249 Query: 474 NYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN 533 Y + +D+AL++L F PICLP V+GWG + Sbjct: 250 QYDPNTFENDVALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPE 306 Query: 534 ILQKVNIPLVTNEECQKRYQDY--KITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGM 589 L ++ IP+V + CQK Y K+T+ M+CAG KEGGKDAC GDSGGP+V + G Sbjct: 307 TLMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQ 366 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 W LVG SWG+ C ++++ GVY+ + DWI T Sbjct: 367 WYLVGTVSWGDDCGKKDRYGVYSYIHHNKDWIQRVT 402 >3BSQ-A nrPDB Length = 227 Score = 244 bits (622), Expect = 1e-64, Method: Composition-based stats. Identities = 77/238 (32%), Positives = 120/238 (50%), Gaps = 19/238 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G + G PWQV+L L+ + CGG L+ +WVLTAAHC + + ++ G Sbjct: 1 IIDGAPCARGSHPWQVAL---LSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 L D + + + H Y +D+ L+KL + + K + LPS+ + Sbjct: 53 SDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE- 109 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T C V+GWG + + L V++ L++ ++C K Y+D + M+CAG + Sbjct: 110 -PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDS 167 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQ 626 K+AC GDSGGPLVC L G+ SWG C + PGVYT+V ++ WI + + Sbjct: 168 KKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1SGF-A nrPDB Length = 240 Score = 244 bits (622), Expect = 1e-64, Method: Composition-based stats. Identities = 77/242 (31%), Positives = 125/242 (51%), Gaps = 28/242 (11%) Query: 400 GEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITK 459 PW V++ ++ CGG L+ WVLTAAHC+ D ++++ G N + Sbjct: 13 NSQPWHVAVYRF---NKYQCGGVLLDRNWVLTAAHCY-----NDKYQVWLGKNNFLEDEP 64 Query: 460 DTPFSQIKEIIIHQNYKV-----------SEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508 + + I H ++ + + ++D+ L++L P + T+ KPI LP++ Sbjct: 65 SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTE- 123 Query: 509 DTSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + + C +GWG + K + + LQ VN+ L+ NE+C K + + K+T M+CAG Sbjct: 124 -EPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAH-EMKVTDAMLCAGEM 181 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKTQ 626 +GG C+ DSGGPL+C L GITSWG E C +P VYTK+ ++ WI E Sbjct: 182 DGGSYTCEHDSGGPLICDG----ILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMA 237 Query: 627 SS 628 ++ Sbjct: 238 NN 239 >1TON-A nrPDB Length = 235 Score = 243 bits (620), Expect = 2e-64, Method: Composition-based stats. Identities = 83/251 (33%), Positives = 126/251 (50%), Gaps = 30/251 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG PWQV++ +LCGG LI WV+TAAHC+ + +++ G Sbjct: 1 IVGGYKCEKNSQPWQVAVI-----NEYLCGGVLIDPSWVITAAHCYS-----NNYQVLLG 50 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKV-----------SEGNHDIALIKLQAPLNYTEFQ 499 NL +++ H +Y + ++D+ L+ L P + T Sbjct: 51 RNNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGV 110 Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKIT 558 K I LP+K + + C +GWG + + + LQ VNI L++NE+C + Y+D +T Sbjct: 111 KVIDLPTK--EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKD-NVT 167 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEY 617 M+CAG EGGKD C GDSGGPL+C L GITS G CA+ + P +Y K+ ++ Sbjct: 168 DVMLCAGEMEGGKDTCAGDSGGPLICDG----VLQGITSGGATPCAKPKTPAIYAKLIKF 223 Query: 618 MDWILEKTQSS 628 WI + + + Sbjct: 224 TSWIKKVMKEN 234 >1FUJ-A nrPDB Length = 221 Score = 242 bits (619), Expect = 2e-64, Method: Composition-based stats. Identities = 71/237 (29%), Positives = 105/237 (44%), Gaps = 17/237 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + P+ SLQ++ H CGG+LI +VLTAAHC +P Q + + G Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP-QRLVNVVLG 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + ++ + NY +DI LI+L +P N + + LP + Sbjct: 60 AHNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 T C GWG +LQ++N+ +VT + +C Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPRRK 168 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQ 626 C GDSGGPL+C + GI S+ GCA R P +T+VA Y+DWI + Sbjct: 169 AGICFGDSGGPLICDG----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >4GSO-A nrPDB Length = 232 Score = 242 bits (619), Expect = 2e-64, Method: Composition-based stats. Identities = 80/242 (33%), Positives = 120/242 (49%), Gaps = 19/242 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG E P+ L + + CG +LI +WV+TAAHC +++ G Sbjct: 1 VLGGDECDINEHPFLAFLY----SHGYFCGLTLINQEWVVTAAHC-----DSTNFQMQLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE-GNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + + +D KE I N +SE + DI LIKL P++ ++ P+ LPS + Sbjct: 52 VHSKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPS--N 109 Query: 510 TSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 ++ + C + GWG + ++ NI LV E CQ Y + +CAG E Sbjct: 110 PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLP-AKTTLCAGVLE 168 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKTQS 627 GGKD C GDSGGPL+C NG + GI S+G C + +PG+YT V +Y DWI Sbjct: 169 GGKDTCVGDSGGPLIC--NGQF--QGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAG 224 Query: 628 SD 629 + Sbjct: 225 NT 226 >1KYN-A nrPDB Length = 235 Score = 242 bits (617), Expect = 5e-64, Method: Composition-based stats. Identities = 69/247 (27%), Positives = 109/247 (44%), Gaps = 13/247 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG S P+ LQ++ A + CGG L+ +VLTAAHC + G Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHC-----WGSNINVTLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + I H Y +DI L++L + P+ LP + Sbjct: 56 AHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEG 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 T C V GWG + L++V + + + +C + + Y +R +C G + Sbjct: 116 LRPGTLCTVAGWGRV-SMRRGTDTLREVQLRVQRDRQCLRIFGSYD-PRRQICVGDRRER 173 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDG 630 K A KGDSGGPL+C + GI S+G+ P V+T+V+ ++ WI +S Sbjct: 174 KAAFKGDSGGPLLCNN----VAHGIVSYGKSSGVP--PEVFTRVSSFLPWIRTTMRSFKL 227 Query: 631 KAQMQSP 637 QM++P Sbjct: 228 LDQMETP 234 >4FXG-H nrPDB Length = 242 Score = 241 bits (616), Expect = 6e-64, Method: Composition-based stats. Identities = 86/247 (34%), Positives = 121/247 (48%), Gaps = 20/247 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAH-CFDGLPLQDVWRIYS 449 I GG + G++PWQV + TA G+L+ WVLTAAH ++ I Sbjct: 1 IYGGQKAKPGDFPWQVLILGGTTA-----AGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKG 508 G L +S + + IH+ Y G ++DIALIKL + PICLP K Sbjct: 56 GTLKRLSPHYTQAWS--EAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKE 113 Query: 509 DTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY-----QDYKITQRM 561 S + T+ +GWG ++ +G + L V+IP+V +++C Y +T M Sbjct: 114 AESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANM 172 Query: 562 VCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYM 618 +CAG + GGKD+C+GD+GG LV W + GI SWG C Q GVYTKV Y+ Sbjct: 173 LCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYI 232 Query: 619 DWILEKT 625 WI Sbjct: 233 PWIENII 239 >2AIQ-A nrPDB Length = 231 Score = 240 bits (613), Expect = 1e-63, Method: Composition-based stats. Identities = 84/242 (34%), Positives = 120/242 (49%), Gaps = 20/242 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG + E + + + LCGG+LI +WVLTA HC G RIY G Sbjct: 1 VIGGDECNINEHRFLALVYANGS----LCGGTLINQEWVLTARHCDRG-----NMRIYLG 51 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE-GNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + NL + KD KE N + + DI LI+L P+ + P+ LPS + Sbjct: 52 MHNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPS--N 109 Query: 510 TSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 ++ + C + GWG + + ++ NI ++ CQ Y+ T +CAG E Sbjct: 110 PPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAAT--TLCAGILE 167 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITS-WGEGCARREQPGVYTKVAEYMDWILEKTQS 627 GGKD CKGDSGGPL+C NG + GI S G CA+ +PG+YTKV +Y DWI Sbjct: 168 GGKDTCKGDSGGPLIC--NGQF--QGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISG 223 Query: 628 SD 629 + Sbjct: 224 NT 225 >4DJZ-B nrPDB Length = 251 Score = 240 bits (612), Expect = 2e-63, Method: Composition-based stats. Identities = 83/252 (32%), Positives = 117/252 (46%), Gaps = 22/252 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-------------D 437 I G + G PW L + CGGSL+G W++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLN--GQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS 58 Query: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497 L ++I G ++ +K +H Y + +D+AL++L Sbjct: 59 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY-- 555 F PICLP V+GWG + L ++ IP+V + CQK Y Sbjct: 119 FVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQKAYAPLKK 175 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARREQPGVYTK 613 K+T+ M+CAG KEGGKDAC GDSGGP+V + G W LVG SWG+ C ++++ GVY+ Sbjct: 176 KVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYSY 235 Query: 614 VAEYMDWILEKT 625 + DWI T Sbjct: 236 IHHNKDWIQRVT 247 >1GPZ-A nrPDB Length = 399 Score = 239 bits (609), Expect = 3e-63, Method: Composition-based stats. Identities = 81/277 (29%), Positives = 129/277 (46%), Gaps = 26/277 (9%) Query: 368 SGYSLRLC--NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIG 425 G + C G V + +I+GG + G +PWQV + GG+L+G Sbjct: 134 KGEKIPRCLPVCGKP-VNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLG 187 Query: 426 HQWVLTAAHCFD----GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGN 481 +W+LTAAH ++ G N+ ++ K I+ + +H +Y+ E Sbjct: 188 DRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLG-NHPIRRVSVHPDYRQDESY 246 Query: 482 H---DIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKV 538 + DIAL++L+ + PICLP + +V+G+G +EK I + L+ V Sbjct: 247 NFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFV 304 Query: 539 NIPLVTNEECQKRYQDYK----ITQRMVCAGYKEGGKDACKGDSGGPLVCKH--NGMWRL 592 +P+ + C+ + +Q M CAG+ +DAC+GDSGG + W Sbjct: 305 RLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVA 364 Query: 593 VGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 GI SWG GC+R G YTKV Y+DWI ++ + D Sbjct: 365 TGIVSWGIGCSRG--YGFYTKVLNYVDWIKKEMEEED 399 >5ZFH-A nrPDB Length = 224 Score = 239 bits (609), Expect = 4e-63, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 118/241 (48%), Gaps = 19/241 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G G PWQV+L L + CGG L+ WVLTAAHC G +++ G Sbjct: 1 IIDGYKCKEGSHPWQVAL---LKGNQLHCGGVLVDKYWVLTAAHCKMGQ-----YQVQLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + D + + + H Y +DI L++L P+ + + + LP + Sbjct: 53 SDKIGD--QSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE- 109 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T+C V+GWG + + L ++ L+++ EC+K Y+D + + M+CAG + Sbjct: 110 -PPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDL-LGKTMLCAGIPDS 167 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKTQSS 628 + C GDSGGPLVC L G+ SWG C + PGVYT+V +Y W++E ++ Sbjct: 168 KTNTCNGDSGGPLVCNDT----LQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 Query: 629 D 629 Sbjct: 224 R 224 >1ZJK-A nrPDB Length = 403 Score = 239 bits (609), Expect = 4e-63, Method: Composition-based stats. Identities = 93/270 (34%), Positives = 129/270 (47%), Gaps = 27/270 (10%) Query: 371 SLRLCNTGDNSVCTTK---TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQ 427 SL +C VC T +I GG + G++PWQV + TA G+L+ Sbjct: 143 SLPVCEP----VCGLSARTTGGQIYGGQKAKPGDFPWQVLILGGTTA-----AGALLYDN 193 Query: 428 WVLTAAH-CFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIA 485 WVLTAAH ++ I G L +S + + IH+ Y G ++DIA Sbjct: 194 WVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWS--EAVFIHEGYTHDAGFDNDIA 251 Query: 486 LIKLQAPLNYTEFQKPICLPSKGDTSTIYTN--CWVTGWGFSKEKGEIQNILQKVNIPLV 543 LIKL + PICLP K S + T+ +GWG ++ +G + L V+IP+V Sbjct: 252 LIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIV 310 Query: 544 TNEECQKRY-----QDYKITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGIT 596 +++C Y +T M+CAG + GGKD+C+GDSGG LV W + GI Sbjct: 311 DHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIV 370 Query: 597 SWGE-GCARREQPGVYTKVAEYMDWILEKT 625 SWG C Q GVYTKV Y+ WI Sbjct: 371 SWGSMNCGEAGQYGVYTKVINYIPWIENII 400 >1MD7-A nrPDB Length = 328 Score = 238 bits (608), Expect = 4e-63, Method: Composition-based stats. Identities = 80/274 (29%), Positives = 128/274 (46%), Gaps = 26/274 (9%) Query: 368 SGYSLRLC--NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIG 425 G + C G V + RI+GG + G +PWQV + GG+L+G Sbjct: 66 KGEKIPRCLPVCGKP-VNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLG 119 Query: 426 HQWVLTAAHCFD----GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGN 481 +W+LTAAH ++ G N+ ++ K I+ + +H +Y+ E Sbjct: 120 DRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLG-NHPIRRVSVHPDYRQDESY 178 Query: 482 H---DIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKV 538 + DIAL++L+ + PICLP + +V+G+G +EK I + L+ V Sbjct: 179 NFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFV 236 Query: 539 NIPLVTNEECQKRYQDYK----ITQRMVCAGYKEGGKDACKGDSGGPLVCKH--NGMWRL 592 +P+ + C+ + +Q M CAG+ +DAC+GD+GG + W Sbjct: 237 RLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVA 296 Query: 593 VGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 GI SWG GC+R G YTKV Y+DWI ++ + Sbjct: 297 TGIVSWGIGCSRG--YGFYTKVLNYVDWIKKEME 328 >2QY0-B nrPDB Length = 242 Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats. Identities = 77/252 (30%), Positives = 122/252 (48%), Gaps = 23/252 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD----GLPLQDVWR 446 I+GG + G +PWQV + GG+L+G +W+LTAAH Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 447 IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH---DIALIKLQAPLNYTEFQKPIC 503 ++ G N+ ++ K I+ + +H +Y+ E + DIAL++L+ + PIC Sbjct: 56 VFLGHTNVEELMKLG-NHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 114 Query: 504 LPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK----ITQ 559 LP + +V+G+G +EK I + L+ V +P+ + C+ + +Q Sbjct: 115 LPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 172 Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQPGVYTKVAEY 617 M CAG+ +DAC+GDSGG + W GI SWG GC+R G YTKV Y Sbjct: 173 NMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRG--YGFYTKVLNY 230 Query: 618 MDWILEKTQSSD 629 +DWI ++ + D Sbjct: 231 VDWIKKEMEEED 242 >1MZD-A nrPDB Length = 240 Score = 236 bits (603), Expect = 2e-62, Method: Composition-based stats. Identities = 80/240 (33%), Positives = 116/240 (48%), Gaps = 13/240 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG S P+ S+Q H+CGG LI QWVLTAAHC + G Sbjct: 3 IIGGKEVSPHSRPFMASIQY---GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLG 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +LS +IK+ I ++DI L+KLQ + K + + SK Sbjct: 60 AHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSL 119 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKR---YQDYKITQRMVCAGY 566 + T C VTGWG + + L++V + +++ + C + D IT+ MVCAG Sbjct: 120 RS-GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGD 178 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA-EYMDWILEKT 625 +G KD+CKGD+GGPL+CK G++ I S G C +PG+YT + +Y WI Sbjct: 179 AKGQKDSCKGDAGGPLICK--GVFHA--IVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >1ORF-A nrPDB Length = 234 Score = 236 bits (601), Expect = 3e-62, Method: Composition-based stats. Identities = 69/242 (28%), Positives = 114/242 (47%), Gaps = 17/242 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ V L + ++ +C G+LI WVLTAAHC L ++ G Sbjct: 1 IIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHC----NLNKRSQVILG 53 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +++ +K+ + Y + D+ L++L ++ + LP KGD Sbjct: 54 AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDD 113 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQ---DYKITQRMVCAGYK 567 T C V GWG + + L++V I ++ + C R + I MVCAG Sbjct: 114 VKPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 173 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVA-EYMDWILEK 624 GG+D+C GDSG PL+C+ G+TS+G C PGVY ++ ++++WI+ Sbjct: 174 RGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 229 Query: 625 TQ 626 + Sbjct: 230 IK 231 >5O32-I nrPDB Length = 244 Score = 235 bits (600), Expect = 4e-62, Method: Composition-based stats. Identities = 89/237 (37%), Positives = 126/237 (53%), Gaps = 13/237 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + G+ PWQV+++ A CGG IG W+LTAAHC ++I++ Sbjct: 1 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTH-RYQIWTT 56 Query: 451 ILN-LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK----PICLP 505 +++ + K + II H+NY +DIALI+++ N + + P C+P Sbjct: 57 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 116 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565 C V+GWG K+ + + LQ + L++N C K Y + + M CAG Sbjct: 117 WSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAG 173 Query: 566 YKEGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621 +G DACKGDSGGPLVC N + + G+ SWGE C + E PGVYTKVA Y DWI Sbjct: 174 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 230 >3S9B-A nrPDB Length = 234 Score = 235 bits (600), Expect = 4e-62, Method: Composition-based stats. Identities = 76/241 (31%), Positives = 118/241 (48%), Gaps = 15/241 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGG + E P+ V+L ++ H C G+LI +WVLTAAHC + RI G Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHC-----DRRNIRIKLG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + + +D + N K + + DI LI+L+ P+ Y+ P+ LPS+ Sbjct: 55 MHSKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRS- 113 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + + C + GWG ++ NI +V ++ C+ Y R +CAG +G Sbjct: 114 -RGVGSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKG 171 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKTQSS 628 G+D C GDSGGPL+C + GI + G E C + +P VYTKV +Y +WI + Sbjct: 172 GRDTCHGDSGGPLICNG----EMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 Query: 629 D 629 Sbjct: 228 R 228 >4BXW-A nrPDB Length = 423 Score = 235 bits (599), Expect = 6e-62, Method: Composition-based stats. Identities = 77/264 (29%), Positives = 126/264 (47%), Gaps = 19/264 (7%) Query: 385 TKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 444 RIV G + GE PWQ +L + + CGG+++ +VLTAAHC + Sbjct: 164 PSPDIRIVNGMDCKLGECPWQAALVDEK--EGVFCGGTILSPIYVLTAAHCI---NETET 218 Query: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSE---------GNHDIALIKLQAPLNY 495 + G ++ S I P + +I +H+ + + ++DIA+I+++ P+ + Sbjct: 219 ISVVVGEIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQF 277 Query: 496 TEFQKPICLPSKGDTSTIYTN---CWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY 552 +E P CLP+ + + V+G+G EKG L+ + +P V C Sbjct: 278 SENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVS- 336 Query: 553 QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYT 612 + IT M CAGY +DAC+GDSGGP + + GI S GEGCAR + G YT Sbjct: 337 SETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYT 396 Query: 613 KVAEYMDWILEKTQSSDGKAQMQS 636 K+++++ WI + + + Sbjct: 397 KLSKFIPWIKRIMRQKLPSTESST 420 >4Q7Y-A nrPDB Length = 250 Score = 234 bits (597), Expect = 8e-62, Method: Composition-based stats. Identities = 65/247 (26%), Positives = 110/247 (44%), Gaps = 12/247 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + P+ S++ +H CGG L+ +WV++AAHCF L+ + G Sbjct: 1 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP-SKGD 509 LS I + H +Y +DI L++L + LP + Sbjct: 57 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRAR 116 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T T C V GWGF + E+ L + + ++ + C ++ + +T M+C + Sbjct: 117 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDS 175 Query: 570 -GKDACKGDSGGPLVCKHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWILEKTQS 627 + C DSGGPLVC++ G+ S+ G C + P VYT+V+ ++ WI + + Sbjct: 176 HRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 231 Query: 628 SDGKAQM 634 S + Sbjct: 232 SSPQPGP 238 >3RP2-A nrPDB Length = 224 Score = 234 bits (596), Expect = 1e-61, Method: Composition-based stats. Identities = 71/237 (29%), Positives = 107/237 (45%), Gaps = 16/237 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GG S P+ L + R +CGG LI Q+VLTAAHC + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC-----KGREITVIL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G ++ ++++ IIH++Y HDI L+KL+ + T + LPS D Sbjct: 56 GAHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSD 115 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVCAGYKE 568 CW GWG + + L++V + ++ + C RY +YK VC G Sbjct: 116 FIHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKF---QVCVGSPT 172 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 + A GDSGGPL+C GI S+G A+ P ++T+V+ Y+ WI Sbjct: 173 TLRAAFMGDSGGPLLCAG----VAHGIVSYGHPDAKP--PAIFTRVSTYVPWINAVI 223 >4E7N-A nrPDB Length = 238 Score = 233 bits (594), Expect = 2e-61, Method: Composition-based stats. Identities = 81/247 (32%), Positives = 125/247 (50%), Gaps = 17/247 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG + E + V+L ++ CGG+LI +WVLTAAHC + +RI G Sbjct: 1 IIGGDECNINEHRFLVALY-TSRSRTLFCGGTLINQEWVLTAAHC-----DRKNFRIKLG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIH-QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + +D KE + + + DI LI+L +P+ ++ P Sbjct: 55 MHSKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSS 112 Query: 510 TSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQKRYQDYKI--TQRMVCAGY 566 ++ + C + GWG G ++ VNI L+ E C+ Y ++++ T R +CAG Sbjct: 113 PPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGI 172 Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKT 625 EGGKD CKGDSGGPL+C NG + GI SWG + CA+ +P YTKV +++DWI Sbjct: 173 LEGGKDTCKGDSGGPLIC--NGQF--QGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 Query: 626 QSSDGKA 632 + + Sbjct: 229 AGNTDAS 235 >2OLG-A nrPDB Length = 278 Score = 233 bits (594), Expect = 2e-61, Method: Composition-based stats. Identities = 86/269 (31%), Positives = 137/269 (50%), Gaps = 24/269 (8%) Query: 380 NSVCTTKT-STRIVGGTNSSWGEWPWQVSLQVKLTAQ--RHLCGGSLIGHQWVLTAAHCF 436 + C + + +I+ G ++ E+PW + K ++ + CGGSLI +++++TAAHC Sbjct: 11 PNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCV 70 Query: 437 DGLPLQDVW---RIYSGILN----------LSDITKDTPF-SQIKEIIIHQNYKVSEGN- 481 G L+ V ++ G N + D P I+E I H +Y + Sbjct: 71 AGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDR 130 Query: 482 -HDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI 540 HDIALI+L + +T + +P+CLP + + V GWG + E G+ I QK+ + Sbjct: 131 YHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKLAV 189 Query: 541 PLVTNEECQKRYQ--DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKH-NGMWRLVGITS 597 P+V E+C K + ++ +CAG E KD+C GDSGGPL+ + N + L G+ S Sbjct: 190 PVVHAEQCAKTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVS 248 Query: 598 WGEGCARREQPGVYTKVAEYMDWILEKTQ 626 +G C PG+YTKV +Y DWI + Sbjct: 249 FGATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >2ZKS-A nrPDB Length = 240 Score = 233 bits (594), Expect = 2e-61, Method: Composition-based stats. Identities = 77/241 (31%), Positives = 113/241 (46%), Gaps = 13/241 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG P+ SLQ HLCGG L+ +WVLTAAHC Q R+ G Sbjct: 1 IIGGREVIPHSRPYMASLQRN---GSHLCGGVLVHPKWVLTAAHCLAQRMAQ--LRLVLG 55 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKV-SEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + L IK I H YK +D+AL++L + + +P+ LPSK Sbjct: 56 LHTLDSP---GLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQ 112 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVCAGYKE 568 T C + GWG + + G + +L+++++ ++ C R+ + ++ MVC Sbjct: 113 VVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADS 172 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWILEKTQS 627 + CKGDSGGPLVC L G+ S+ C +P V T VA Y+ WI + T Sbjct: 173 KDQAPCKGDSGGPLVCGKG--RVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGR 230 Query: 628 S 628 S Sbjct: 231 S 231 >1YM0-A nrPDB Length = 238 Score = 231 bits (589), Expect = 7e-61, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 124/242 (51%), Gaps = 8/242 (3%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + E+PWQVS++ K ++ H CGGS+I +WV+ AAHC G V + G Sbjct: 1 IVGGIEARPYEFPWQVSVRRK-SSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVV-G 58 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + S + + I +++NY + +D+++IK + + PIC P + Sbjct: 59 EHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND 118 Query: 511 STIYTNCWVTGWGFSKEKGE-IQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 +Y +GWG G +L+ V + + TN C Y I M+CA G Sbjct: 119 Y-VYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTG 177 Query: 570 --GKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 +D+C+GDSGGPL K +G++ LVGI SWG GCA PGVY++V + WI + Sbjct: 178 MTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCA-SGYPGVYSRVGFHAGWITDTIT 236 Query: 627 SS 628 ++ Sbjct: 237 NN 238 >1BQY-A nrPDB Length = 234 Score = 230 bits (587), Expect = 1e-60, Method: Composition-based stats. Identities = 76/242 (31%), Positives = 119/242 (49%), Gaps = 17/242 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 + GG + E SL V + LCGG+LI WV+TAAHC + +++ G Sbjct: 1 VFGGDECNINEHR---SLVVLFNSNGFLCGGTLINQDWVVTAAHC-----DSNNFQLLFG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQN-YKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + + +D KE N K E + DI LIKL + ++ +E P+ Sbjct: 53 VHSKKILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSS 110 Query: 510 TSTIYTNCWVTGWGFS-KEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 ++ + C + GWG + K ++ NI ++ + C+ Y ++ +CAG + Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWILEKTQS 627 GG+D C DSGGPL+C NG++ GI SW G C + +PGVYTKV +Y+DWI Sbjct: 171 GGRDTCHFDSGGPLIC--NGIF--QGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAG 226 Query: 628 SD 629 + Sbjct: 227 NK 228 >5UBM-A nrPDB Length = 252 Score = 229 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 76/260 (29%), Positives = 121/260 (46%), Gaps = 33/260 (12%) Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 RI+GG+++ +PWQV GG+LI WVLTAAH +G ++ + S Sbjct: 1 RIIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPTMY-VGS 53 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKV-------SEGNHDIALIKLQAPLNYTEFQKPI 502 + S + K + + + IH +K+ + ++DIAL++L+ P+ PI Sbjct: 54 TSVQTSRLAKSKMLTP-EHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 112 Query: 503 CLP--SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ--------KRY 552 CLP S ++GWG + EK + L+ +P+ +C+ Sbjct: 113 CLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 553 QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG---MWRLVGITSWGEGCARREQPG 609 + Y T M+CAG E G D+CKGDSGG + + G+ SWG C G Sbjct: 172 EAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT---YG 227 Query: 610 VYTKVAEYMDWILEKTQSSD 629 +YT+V Y+DWI++ Q + Sbjct: 228 LYTRVKNYVDWIMKTMQENS 247 >2XRC-A nrPDB Length = 565 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 100/327 (30%), Positives = 149/327 (45%), Gaps = 25/327 (7%) Query: 313 KGVNVCQETCT-KMIRCQFFTYSLLPEDCK--------EEKCKCFLRLSMDGSPTRIAYG 363 + +C + C K C+ C E++ C S+ T I Sbjct: 232 QSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVAQEETEILTA 291 Query: 364 TQGSSGYSLRLCNTGDNSVCTTKT---STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG 420 + ++ + + RIVGG + G+ PWQV+++ A CG Sbjct: 292 DMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIK---DASGITCG 348 Query: 421 GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILN-LSDITKDTPFSQIKEIIIHQNYKVSE 479 G IG W+LTAAHC ++I++ +++ + K + II H+NY Sbjct: 349 GIYIGGCWILTAAHCLRASKTH-RYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGT 407 Query: 480 GNHDIALIKLQAPLNYTEFQK----PICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNIL 535 +DIALI+++ N + + P C+P C V+GWG K+ + + L Sbjct: 408 YQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-L 466 Query: 536 QKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKH-NGMWRLVG 594 Q + L++N C K Y + + M CAG +G DACKGDSGGPLVC N + + G Sbjct: 467 QWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWG 524 Query: 595 ITSWGEGCARREQPGVYTKVAEYMDWI 621 + SWGE C + E PGVYTKVA Y DWI Sbjct: 525 VVSWGENCGKPEFPGVYTKVANYFDWI 551 >5KWM-A nrPDB Length = 230 Score = 229 bits (583), Expect = 4e-60, Method: Composition-based stats. Identities = 82/238 (34%), Positives = 129/238 (54%), Gaps = 15/238 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG +++ + P+ V+L + CGG+L V+TAAHC G D + SG Sbjct: 1 IVGGEDANVQDHPFTVALV--TPDGQQFCGGTLAAPNKVVTAAHCTVGSQPAD-INVVSG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +S S++ + +H Y+ + D++++ L+AP+ + PI L D Sbjct: 58 RTVMSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVK----EAPIELAKADDA 111 Query: 511 -STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T + GWG + E G+ + LQK +P+ +++ C++ Y +Y MVCAG EG Sbjct: 112 GYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYT-PDAMVCAGVPEG 170 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 G D C+GDSGGP+V + L+G+TSWGEGCAR +PGVY +V Y D ++E+ + Sbjct: 171 GVDTCQGDSGGPMVVNNK----LIGVTSWGEGCARPGKPGVYARVGAYYDVLMEQINA 224 >2B9L-A nrPDB Length = 394 Score = 228 bits (581), Expect = 6e-60, Method: Composition-based stats. Identities = 83/266 (31%), Positives = 128/266 (48%), Gaps = 22/266 (8%) Query: 382 VCTTKTSTRIVGGT-NSSWGEWPWQVSLQ-----VKLTAQRHLCGGSLIGHQWVLTAAHC 435 +I G T + +GE+PW V++ ++ +CGGSLI VLT AHC Sbjct: 121 RNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHC 180 Query: 436 FDGLPLQ-DVWRIYSGILNLSDITKDTPF--SQIKEIIIHQNYKVSEGNHDIALIKLQAP 492 + D +I +G + + P+ +I+++IIH N+ +D+AL+ L P Sbjct: 181 VNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRP 240 Query: 493 LNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGE--IQNILQKVNIPLVTNEECQK 550 L + ICLP + T C+ +GWG + NIL+K+ +P V ++CQ Sbjct: 241 LVQADNIGTICLPQQSQIF-DSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQA 299 Query: 551 RYQDYKI------TQRMVCAGYKEGGKDACKGDSGGPLVCKHN---GMWRLVGITSWGEG 601 ++ ++ Q VCAG E GKD C GD G PL C + +GI +WG G Sbjct: 300 DLRNTRLGLKFVLDQTFVCAG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIG 358 Query: 602 CARREQPGVYTKVAEYMDWILEKTQS 627 C PGVY VA + +WI ++ Q+ Sbjct: 359 CGDENVPGVYANVAHFRNWIDQEMQA 384 >1ELV-A nrPDB Length = 333 Score = 228 bits (581), Expect = 6e-60, Method: Composition-based stats. Identities = 80/283 (28%), Positives = 126/283 (44%), Gaps = 36/283 (12%) Query: 369 GYSLRLCN--TGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGH 426 G L C G + RI+GG+++ +PWQV GG+LI Sbjct: 60 GPELPKCVPVCGVP-REPFEEKQRIIGGSDADIKNFPWQVFF------DNPWAGGALINE 112 Query: 427 QWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKV-------SE 479 WVLTAAH +G ++ + S + S + K + + + IH +K+ + Sbjct: 113 YWVLTAAHVVEGNREPTMY-VGSTSVQTSRLAKSKMLTP-EHVFIHPGWKLLAVPEGRTN 170 Query: 480 GNHDIALIKLQAPLNYTEFQKPICLP--SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQK 537 ++DIAL++L+ P+ PICLP S ++GWG + EK + L+ Sbjct: 171 FDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKA 229 Query: 538 VNIPLVTNEECQ--------KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG- 588 +P+ +C+ + Y T M+CAG E G D+CKGDSGG + Sbjct: 230 ARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPND 288 Query: 589 --MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 + G+ SWG C G+YT+V Y+DWI++ Q + Sbjct: 289 KTKFYAAGLVSWGPQCGT---YGLYTRVKNYVDWIMKTMQENS 328 >1OP0-A nrPDB Length = 234 Score = 227 bits (580), Expect = 9e-60, Method: Composition-based stats. Identities = 75/242 (30%), Positives = 116/242 (47%), Gaps = 17/242 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG E + V+ CGG+LI +WV+TAAHC +++ G Sbjct: 1 VIGGNECDINEHRFLVAF---FNTTGFFCGGTLINPEWVVTAAHC-----DSTDFQMQLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE-GNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + + +D KE I N +E + DI LIKL P++ ++ P+ Sbjct: 53 VHSKKVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSS 110 Query: 510 TSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 ++ + C + GWG + K ++ NI L+ + CQ Y + R +CAG + Sbjct: 111 PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKTQS 627 GGKD C GDSGGPL+C NG + GI S+G C + +PG+YT V +Y DWI Sbjct: 171 GGKDTCGGDSGGPLIC--NGQF--QGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAG 226 Query: 628 SD 629 + Sbjct: 227 NT 228 >1GVZ-A nrPDB Length = 237 Score = 227 bits (579), Expect = 1e-59, Method: Composition-based stats. Identities = 77/252 (30%), Positives = 123/252 (48%), Gaps = 28/252 (11%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG PWQV++ + CGG L+ QWVLTAAHC D ++I+ G Sbjct: 1 IIGGWECEKHSKPWQVAVYHQ---GHFQCGGVLVHPQWVLTAAHCMS-----DDYQIWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKV-----------SEGNHDIALIKLQAPLNYTEFQ 499 NLS F Q+ + + + + + +HD+ L++L P T+ Sbjct: 53 RHNLSKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAV 112 Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQKRYQDYKIT 558 K + LP++ + + C+ +GWG LQ V + L +NE+C + Y + K+T Sbjct: 113 KILDLPTQ--EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPE-KMT 169 Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEY 617 + ++CA +++ C GDSGG L+C +G++ GITSWG CA V+TKV + Sbjct: 170 EFVLCATHRDDSGSICLGDSGGALIC--DGVF--QGITSWGYSECADFNDNFVFTKVMPH 225 Query: 618 MDWILEKTQSSD 629 WI E + + Sbjct: 226 KKWIKETIEKNS 237 >2XXL-A nrPDB Length = 408 Score = 227 bits (578), Expect = 1e-59, Method: Composition-based stats. Identities = 85/282 (30%), Positives = 130/282 (46%), Gaps = 28/282 (9%) Query: 379 DNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVK-LTAQRHLCGGSLIGHQWVLTAAHCFD 437 +N C S R+ G PW L+ + R LCGG++I +++LTAAHC Sbjct: 107 ENFDCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVH 166 Query: 438 GLPLQDVWRIYSGILNLSDITKDTPF------------SQIKEIIIHQNYKVSEGNHDIA 485 GL D++ I G +S I++ +IH+ Y HDIA Sbjct: 167 GLQ-NDLYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIA 225 Query: 486 LIKLQAPLNYTEFQKPICLPSKGDT---STIYTNCWVTGWGFSKEKGEIQNILQKVNIPL 542 L+KL + + + KPICLP + + + +VTGWG + E G ++L + N+PL Sbjct: 226 LLKLNRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWG-TTENGSSSDVLLQANVPL 284 Query: 543 VTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLV------GIT 596 C + Y+ + +C G + +D+CKGDSGGPL + GI Sbjct: 285 QPRSACSQAYR-RAVPLSQLCVGGGDL-QDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIV 342 Query: 597 SWG-EGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSP 637 S G C + PG+YT V EY+ WI + +S+G + + P Sbjct: 343 SQGVVTCGQISLPGLYTNVGEYVQWITDTM-ASNGLLESRGP 383 >2BDH-A nrPDB Length = 223 Score = 226 bits (577), Expect = 2e-59, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 121/239 (50%), Gaps = 18/239 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+ G + S PWQ +L ++ C G L+ QWVL+AAHCF Q+ + I G Sbjct: 1 IINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLG 52 Query: 451 ILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + +L D + + + H Y +D+ LIKL ++ ++ + I + S+ Sbjct: 53 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ-- 110 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T +C V+GWG G + +LQ VN+ +V+ E C K Y D M CAG + Sbjct: 111 CPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGQD 168 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQS 627 KD+C GDSGGPL+C L G+ S+G+ C + PGVYT + ++ +WI + Q+ Sbjct: 169 QKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >2RDL-A nrPDB Length = 226 Score = 226 bits (576), Expect = 3e-59, Method: Composition-based stats. Identities = 59/239 (24%), Positives = 103/239 (43%), Gaps = 14/239 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+GGT P+ L++ C G LI +V+TAAHC + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC-----AGRSITVLL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G N ++++ H Y +DI L+KL+ N T + + +K + Sbjct: 56 GAHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSN 115 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + C GWG + + LQ+V + ++ + C K ++D+ + +C G + Sbjct: 116 SIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQAC-KHFEDFH-QEPQLCVGNPKK 173 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 ++ KGDSGGPL+C GI S+ A+ P V+T+++ Y WI + + + Sbjct: 174 IRNVYKGDSGGPLLCAG----IAQGIASYVLRNAKP--PSVFTRISHYRPWINKILREN 226 >1EQ9-A nrPDB Length = 222 Score = 226 bits (575), Expect = 3e-59, Method: Composition-based stats. Identities = 72/237 (30%), Positives = 129/237 (54%), Gaps = 15/237 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG ++ G++P+QVSL++ + H CG S++ + VLTAAHC DGL + +++ G Sbjct: 1 IVGGKDAPVGKYPYQVSLRL---SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 LS + +++ ++++NY +D+AL+ L P+ + + +PI L + + Sbjct: 58 TNYLS---ESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDED 114 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C +TGWG ++ G N LQ++ + + ++C++ +++ +C + G Sbjct: 115 LE-SNPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERD--QWRVIDSHICT-LTKRG 170 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 + AC GDSGGPLV +GI S+G CA +P VYT+V+ ++ WI + Sbjct: 171 EGACHGDSGGPLVANG----AQIGIVSFGSPCAL-GEPDVYTRVSSFVSWINANLKK 222 >1AZZ-A nrPDB Length = 226 Score = 226 bits (575), Expect = 3e-59, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 121/238 (50%), Gaps = 19/238 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + WP Q +L + + CGGSLI +W+LTAAHC DG D + G Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDGAGFVD---VVLG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 N+ + Q + +H+NY ++DIA+I+L P+ T + LPS Sbjct: 55 AHNIREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPS--TD 112 Query: 511 STIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 + T TGWG + I ++L++V++P+++N +C Y +T +C G Sbjct: 113 VGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG--IVTDGNICI-DSTG 169 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWILEKT 625 GK C GDSGGPL +NG+ GITS+G GC P +T+V ++DWI +T Sbjct: 170 GKGTCNGDSGGPL--NYNGLTY--GITSFGAAAGC-EAGYPDAFTRVTYFLDWIQTQT 222 >6BQM-A nrPDB Length = 506 Score = 224 bits (570), Expect = 1e-58, Method: Composition-based stats. Identities = 79/249 (31%), Positives = 130/249 (52%), Gaps = 17/249 (6%) Query: 387 TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 446 S+RI+GG ++ GEWP+ V+L + ++ CGGS +G ++VLTAAHC D Sbjct: 7 VSSRIIGGEQATAGEWPYMVALTARNSSH-VFCGGSYLGGRYVLTAAHCVDKEDPAKG-D 64 Query: 447 IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506 + G +++D+ +++I +H +Y + +DIA+++L+ + I S Sbjct: 65 VLLGAFDMNDVNTAERIH-VRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSS 122 Query: 507 KGDTSTIYTNCWVTGWGFSKE----KGEIQNILQKVNIPLVTNEECQKRYQD-------Y 555 + T + V G+G KE K + IL +V +P V EC+ + D Sbjct: 123 DFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYS 182 Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 615 ++T CAG GKDAC GD+GGP+ N + +G+ SWG+GC R PGVYT ++ Sbjct: 183 QLTNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLS 240 Query: 616 EYMDWILEK 624 + DW+ ++ Sbjct: 241 VFNDWLDDQ 249 >3I77-A nrPDB Length = 230 Score = 224 bits (570), Expect = 1e-58, Method: Composition-based stats. Identities = 80/239 (33%), Positives = 114/239 (47%), Gaps = 12/239 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGGT ++ GE+P+ V L + CGG+L VLTAAHC G G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEG--FCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +++L + + +++ + D ALIKL P+N + T Sbjct: 59 VVDL--QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGT 116 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE-G 569 V GWG ++E G Q L K N+P V++ C+ + M+CAGY + G Sbjct: 117 F------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 570 GKDACKGDSGGPLVCKHN-GMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 G D C+GDSGGP+ K N W VGI SWG GCAR PGVYT+V+ + I ++ Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIASAART 229 >3S69-A nrPDB Length = 234 Score = 222 bits (566), Expect = 4e-58, Method: Composition-based stats. Identities = 79/248 (31%), Positives = 116/248 (46%), Gaps = 17/248 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GG + E SL + C G+LI +WVLTAAHC +++ G Sbjct: 1 VIGGDECNINEHR---SLVAFFNSTGFFCSGTLINEEWVLTAAHC-----DNTNFQMKLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE-GNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 + + + +D KE I N K E + DI LIKL + ++ +E + L Sbjct: 53 VHSKKVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSS 110 Query: 510 TSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568 ++ + C + GWG + K ++ I L+ + CQ Y + R +CAG E Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 569 GGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILEKTQS 627 GGKD C GDSGGPL+C NG + GI S+G C + +PGVYTKV +Y WI Sbjct: 171 GGKDTCGGDSGGPLIC--NGQF--QGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAG 226 Query: 628 SDGKAQMQ 635 + Q Sbjct: 227 NTTVTCPQ 234 >4J1Y-A nrPDB Length = 397 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 79/283 (27%), Positives = 125/283 (44%), Gaps = 36/283 (12%) Query: 369 GYSLRLCN--TGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGH 426 G L C G + R +GG+++ +PWQV GG+LI Sbjct: 124 GPELPKCVPVCGVP-REPFEEKARAIGGSDADIKNFPWQVFF------DNPWAGGALINE 176 Query: 427 QWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKV-------SE 479 WVLTAAH +G ++ + S + S + K + + + IH +K+ + Sbjct: 177 YWVLTAAHVVEGNREPTMY-VGSTSVQTSRLAKSKMLTP-EHVFIHPGWKLLEVPEGRTN 234 Query: 480 GNHDIALIKLQAPLNYTEFQKPICLP--SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQK 537 ++DIAL++L+ P+ PICLP S ++GWG + EK + L+ Sbjct: 235 FDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKA 293 Query: 538 VNIPLVTNEECQ--------KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNG- 588 +P+ +C+ + Y T M+CAG E G D+CKGDSGG + Sbjct: 294 ARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPND 352 Query: 589 --MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 629 + G+ SWG C G+YT+V Y+DWI++ Q + Sbjct: 353 KTKFYAAGLVSWGPQCGT---YGLYTRVKNYVDWIMKTMQENS 392 >2FMJ-A nrPDB Length = 222 Score = 219 bits (559), Expect = 2e-57, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 118/238 (49%), Gaps = 18/238 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGGT ++ GE+P+ V L + CGG+L VLTAAHC G G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +++L + + +++ + Q + D ALIKL P+N + T Sbjct: 54 VVDL----QSSSAVKVRSTKVLQAPGYNGTGKDWALIKLAQPINQPTLKIATTTAYNQGT 109 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 V GWG ++E G Q L K N+P V++ C+ Y + + +CAGY GG Sbjct: 110 F------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGG 163 Query: 571 KDACKGDSGGPLVCKHN-GMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 D C+GDSGGP+ K N W VGI SWGEGCAR+ + GVYT+V+ + I ++ Sbjct: 164 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAART 221 >3BEU-A nrPDB Length = 224 Score = 218 bits (555), Expect = 7e-57, Method: Composition-based stats. Identities = 78/238 (32%), Positives = 114/238 (47%), Gaps = 16/238 (6%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 +VGGT ++ GE+P+ V L + CGG+L VLTAAHC G G Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +++L + + +++ + D ALIKL P+N + T Sbjct: 54 VVDL--QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTAYNQGT 111 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 V GWG ++E G Q L K N+P V++ C+ + M+CAGY Sbjct: 112 F------TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQ 165 Query: 571 KDACKGDSGGPLVCKHN-GMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 +D C+GDSGGP+ K N W VGI SWGEGCAR+ + GVYT+V+ + I ++ Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAART 223 >5LPF-A nrPDB Length = 234 Score = 216 bits (551), Expect = 2e-56, Method: Composition-based stats. Identities = 76/245 (31%), Positives = 114/245 (46%), Gaps = 27/245 (11%) Query: 394 GTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILN 453 G+ + G PWQVSL L+ C G L+ WVLTAAHC + V + +L Sbjct: 7 GSPCARGSQPWQVSLFNGLSFH---CAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLL- 62 Query: 454 LSDITKDTPFSQIKEIIIHQNYKVSEG--------NHDIALIKLQAPLNYTEFQKPICLP 505 + + ++H Y G HD+ L+KL P+ + + LP Sbjct: 63 -----QGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLP 117 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNI-LQKVNIPLVTNEECQKRYQDYKITQRMVCA 564 + + C V GWG + + N L +I +++ +EC+ Y +T M+CA Sbjct: 118 YR--CAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGV-VTNNMICA 174 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVAEYMDWILE 623 G + G+D C+ DSGGPLVC L GI SWG C + P VYT++ +YM WI + Sbjct: 175 G-LDRGQDPCQSDSGGPLVCDET----LQGILSWGVYPCGSAQHPAVYTQICKYMSWINK 229 Query: 624 KTQSS 628 +S+ Sbjct: 230 VIRSN 234 >4WJG-C nrPDB Length = 315 Score = 216 bits (550), Expect = 3e-56, Method: Composition-based stats. Identities = 75/309 (24%), Positives = 124/309 (40%), Gaps = 36/309 (11%) Query: 344 KCKCFLRLSMDG----SPTRIAYGTQGSSGYSLRLCN--TGDNSVCTTKTSTRIVGGTNS 397 +CK + +L +G + + G L C G RI+GG Sbjct: 19 QCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPK-NPANPVQRILGGHLD 77 Query: 398 SWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDI 457 + G +PWQ + ++ G +LI QW+LT A L + L+ Sbjct: 78 AKGSFPWQAKM---VSHHNLTTGATLINEQWLLTTAKNLF-LNHSENATAKDIAPTLTLY 133 Query: 458 TKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNC 517 +I+++++H NY DI LIKL+ ++ E PICLPSK + + Sbjct: 134 VGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY-AEVGRVG 188 Query: 518 WVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQR----------------M 561 +V+GWG + + L+ V +P+ ++C + Y+ + ++ Sbjct: 189 YVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHT 247 Query: 562 VCAGYKEGGKDACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619 CAG + +D C GD+G W GI S+ + CA E GVY KV D Sbjct: 248 FCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAE-YGVYVKVTSIQD 306 Query: 620 WILEKTQSS 628 W+ + + Sbjct: 307 WVQKTIAEN 315 >1M9U-A nrPDB Length = 241 Score = 213 bits (543), Expect = 2e-55, Method: Composition-based stats. Identities = 80/243 (32%), Positives = 126/243 (51%), Gaps = 12/243 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 ++GGTN+S GE+PWQ+S Q + + H CG SL+ L+A+HC DG+ L + R+ +G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGV-LPNNIRVIAG 59 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAPLNYTEFQKPICLPSKG 508 + SD + + + +H+NY ++DIA++ L ++ + LP+ Sbjct: 60 LWQQSDTSGT-QTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY---QDYKITQRMVCAG 565 + T C ++GWG + + +ILQK +IP++T +C I +C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW----GEGCARREQPGVYTKVAEYMDWI 621 G AC GDSGGPL C G R+VG+TSW G G + P VYT+V+ Y+ WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGT-RVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 Query: 622 LEK 624 + Sbjct: 238 GDN 240 >5XRF-A nrPDB Length = 242 Score = 213 bits (543), Expect = 2e-55, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 117/243 (48%), Gaps = 15/243 (6%) Query: 386 KTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVW 445 K+S ++GG E + + C G+LI +WVL AAHC+ + Sbjct: 2 KSSELVIGGNECDTNEHRFLAAF-FTSRPWTFQCAGTLIHEEWVLAAAHCY-----KRGL 55 Query: 446 RIYSGILNLSDITKDTPFS-QIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504 IY G+ N S D I+E + K+++ D+ L+KL P++ + P+ Sbjct: 56 NIYLGMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS- 114 Query: 505 PSKGDTSTIYTNCWVTGWGF-SKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVC 563 +I + C V GWG S K + ++ NI L+ EC Y D T R++C Sbjct: 115 -LPSSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLC 173 Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWIL 622 AG EGG D C DSGGPL+C +G + GI +G+ CA+ +PG+YT+V+ Y DWI Sbjct: 174 AGVLEGGIDTCNQDSGGPLIC--DGQF--QGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQ 229 Query: 623 EKT 625 Sbjct: 230 NII 232 >4X0L-C nrPDB Length = 259 Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats. Identities = 68/271 (25%), Positives = 111/271 (40%), Gaps = 30/271 (11%) Query: 376 NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC 435 G RI+GG + G +PWQ + ++ G +LI QW+LT A Sbjct: 1 VCGKPK-NPANPVQRILGGHLDAKGSFPWQAKM---VSHHNLTTGATLINEQWLLTTAKN 56 Query: 436 FDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNY 495 L + L+ +I+++++H NY DI LIKL+ ++ Sbjct: 57 LF-LNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSV 111 Query: 496 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDY 555 E PICLPSK + + +V+GWG + + L+ V +P+ ++C + Y+ Sbjct: 112 NERVMPICLPSKDY-AEVGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHYEGS 169 Query: 556 KITQR----------------MVCAGYKEGGKDACKGDSGGPLVCKH--NGMWRLVGITS 597 + ++ CAG + +D C GD+G W GI S Sbjct: 170 TVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILS 229 Query: 598 WGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 + + CA E GVY KV DW+ + + Sbjct: 230 FDKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 259 >4F4O-C nrPDB Length = 347 Score = 212 bits (541), Expect = 3e-55, Method: Composition-based stats. Identities = 74/308 (24%), Positives = 116/308 (37%), Gaps = 36/308 (11%) Query: 345 CKCFLRLSMDGSPTRIAYG----TQGSSGYSLRLCN--TGDNSVCTTKTSTRIVGGTNSS 398 C+ + +L G T +G L C G RI+GG+ + Sbjct: 52 CQTYYKLRTAGDGVYTLDSNKQWTNKVTGEKLPECEAVCGKPK-NPVDQVQRIMGGSLDA 110 Query: 399 WGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDIT 458 G +PWQ + ++ G +LI QW+LT A D + L Sbjct: 111 KGSFPWQAKM---ISHHNLTSGATLINEQWLLTTAKNLRLGHKNDT-KAKDIAPTLRLYV 166 Query: 459 KDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCW 518 +I+++I H DI LIKL+ + E PICLPSK + + Sbjct: 167 GKKQEVEIEKVIFHP----DNSTVDIGLIKLKQKVPVNERVMPICLPSKDY-VNVGLVGY 221 Query: 519 VTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQR----------------MV 562 V+GWG L+ V +P+ E+C + Y+ + ++ Sbjct: 222 VSGWGR-NANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTF 280 Query: 563 CAGYKEGGKDACKGDSGGPLVCK--HNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620 CAG + +D C GD+G + W GI S+ + C R + GVY +V +DW Sbjct: 281 CAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSC-RTAEYGVYVRVTSILDW 339 Query: 621 ILEKTQSS 628 I + Sbjct: 340 IQTTIADN 347 >1PQ7-A nrPDB Length = 224 Score = 212 bits (539), Expect = 4e-55, Method: Composition-based stats. Identities = 85/233 (36%), Positives = 121/233 (51%), Gaps = 13/233 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGGT++S G++P+ VS+ CGGSL+ VLTAAHC G Q ++I +G Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPW---CGGSLLNANTVLTAAHCVSGY-AQSGFQIRAG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 L+ T S + + +H +Y S N+D+A++KL + L + G Sbjct: 57 SLS---RTSGGITSSLSSVRVHPSY--SGNNNDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 511 STIYTNCWVTGWGFSKEKGEIQNI-LQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 ++ V GWG + E G + L KV +P+V+ C+ +Y IT +M CAG G Sbjct: 112 PVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSG 171 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWIL 622 GKD+C+GDSGGP+V N L+G SWG GCAR GVY V +I Sbjct: 172 GKDSCQGDSGGPIVDSSN---TLIGAVSWGNGCARPNYSGVYASVGALRSFID 221 >2ASU-B nrPDB Length = 234 Score = 209 bits (531), Expect = 4e-54, Method: Composition-based stats. Identities = 67/237 (28%), Positives = 114/237 (48%), Gaps = 12/237 (5%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIYS 449 +VGG G PW VSL+ + +H CGGSL+ QW+LTA CF + + ++ Sbjct: 1 VVGGH---PGNSPWTVSLRNR--QGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL 55 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G L + + + + + + G+ + L+KL+ + + ICLP + Sbjct: 56 GTLFQNPQHGEPSL---QRVPVAKMVCGPSGSQ-LVLLKLERSVTLNQRVALICLPPEWY 111 Query: 510 TSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG 569 T C + GWG +K G +L + +++N+EC +++ ++ + +C Sbjct: 112 VVPPGTKCEIAGWGETKGTGN-DTVLNVALLNVISNQECNIKHRG-RVRESEMCTEGLLA 169 Query: 570 GKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 AC+GD GGPL C + W L GI CAR P V+T+V+ ++DWI + + Sbjct: 170 PVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >4LK4-A nrPDB Length = 357 Score = 206 bits (523), Expect = 3e-53, Method: Composition-based stats. Identities = 86/253 (33%), Positives = 128/253 (50%), Gaps = 20/253 (7%) Query: 383 CTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTA--QRHLCGGSLIGHQWVLTAAHCFDGLP 440 T S+RI+ G+N++ EWP V+L + Q CGGS +G ++VLTAAHCFD Sbjct: 3 STADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRS 62 Query: 441 LQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500 V + G +L++ ++ + ++I H +Y S +DIA+++L T Sbjct: 63 AASV-DVIIGAYDLNNSSQGERIAA-QKIYRHLSYSPSNLLNDIAIVELAQ----TSSLP 116 Query: 501 PICL--PSKGDTSTIYTNCWVTGWGFSKEKGE--IQNILQKVNIPLVTNEECQKRYQDYK 556 I L P+ + T V GWG + + ILQ+V++ LV+ CQ Q Sbjct: 117 AITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGI 176 Query: 557 ITQ---RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYT 612 + CA KD+C+GD+GGP+V K G +L GI SWG E CA+ GVYT Sbjct: 177 SSDPNSTNFCAARLT--KDSCQGDAGGPIVVK-TGREQL-GIVSWGDEQCAKTGTYGVYT 232 Query: 613 KVAEYMDWILEKT 625 V+ + DWI + T Sbjct: 233 NVSYFRDWITKHT 245 >1AE5-A nrPDB Length = 225 Score = 205 bits (521), Expect = 6e-53, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 101/233 (43%), Gaps = 20/233 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + ++P+ S+Q RH CGG+LI ++V+TAA CF V + G Sbjct: 1 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNP-GVSTVVLG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 +L + + + + Y + +D+ L++L N T + LP + T Sbjct: 57 AYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNAT 116 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 T C V GWG + G + + VN+ + ++C+ VC G Sbjct: 117 VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR---------PNNVCTGVLTRR 167 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWIL 622 C GD G PLVC+ G+ S+ G C R P +T+VA + DWI Sbjct: 168 GGICNGDGGTPLVCEG----LAHGVASFSLGPCGRG--PDFFTRVALFRDWID 214 >1SI5-H nrPDB Length = 240 Score = 201 bits (511), Expect = 9e-52, Method: Composition-based stats. Identities = 75/240 (31%), Positives = 124/240 (51%), Gaps = 19/240 (7%) Query: 391 IVGG--TNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448 +V G T ++ G W VSL+ + +H+CGGSLI WVLTA CF L+D + + Sbjct: 1 VVNGIPTRTNIG---WMVSLRYR---NKHICGGSLIKESWVLTARQCFPSRDLKD-YEAW 53 Query: 449 SGILNLSDI--TKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506 GI ++ K + +++ Y D+ L+KL P +F I LP+ Sbjct: 54 LGIHDVHGRGDEKCKQVLNVSQLV----YGPEGS--DLVLMKLARPAVLDDFVSTIDLPN 107 Query: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQD-YKITQRMVCAG 565 G T T+C V GWG++ +L+ ++ ++ NE+C + ++ + + +CAG Sbjct: 108 YGSTIPEKTSCSVYGWGYTGLI-NYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG 166 Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 ++ G C+GD GGPLVC+ + M ++G+ G GCA +PG++ +VA Y WI + Sbjct: 167 AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >2HLC-A nrPDB Length = 230 Score = 201 bits (511), Expect = 9e-52, Method: Composition-based stats. Identities = 79/240 (32%), Positives = 117/240 (48%), Gaps = 19/240 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRH-LCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449 I+ G + G +P+Q L + L QR CGGSLI ++W+LTAAHC +Y Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCV---HDAVSVVVYL 57 Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509 G + + + II H + +D+ALIK+ + YT+ +PI LPS + Sbjct: 58 GS---AVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEE 113 Query: 510 TSTIYTNCW--VTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567 + + N W V+GWG S ILQ ++ N+ C + Y I + +C G Sbjct: 114 LNNKFENIWATVSGWGQSNTDTV---ILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDT 169 Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKT 625 GK C GDSGGP V + L+G+ S+ G GC +P +++V YMDWI + T Sbjct: 170 SDGKSPCFGDSGGPFVLSDKNL--LIGVVSFVSGAGC-ESGKPVGFSRVTSYMDWIQQNT 226 >1PPF-E nrPDB Length = 218 Score = 200 bits (508), Expect = 2e-51, Method: Composition-based stats. Identities = 67/237 (28%), Positives = 103/237 (43%), Gaps = 20/237 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IVGG + WP+ VSLQ++ H CG +LI +V++AAHC + ++ V G Sbjct: 1 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAVRV-VLG 56 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 NLS ++ I Y +DI +++L + LP++G Sbjct: 57 AHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 115 Query: 511 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 570 C GWG I ++LQ++N+ +VT C++ VC + Sbjct: 116 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN---------VCTLVRGRQ 165 Query: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQ 626 C GDSG PLVC + GI S+ GCA P + VA++++WI Q Sbjct: 166 AGVCFGDSGSPLVCNG----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >3F1S-B nrPDB Length = 283 Score = 176 bits (447), Expect = 2e-44, Method: Composition-based stats. Identities = 63/278 (22%), Positives = 109/278 (39%), Gaps = 26/278 (9%) Query: 357 PTRIAYGTQGSSGYSL----RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL 412 P + +Y + GY L + C D C TS + + PWQV L Sbjct: 19 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAP----DLQDLPWQVKL--TN 72 Query: 413 TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIH 472 + + CGG +I +VLT A C + R + + ++D +I + +H Sbjct: 73 SEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPLMIKITHVHVH 126 Query: 473 QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTST---IYTNCWVTGWGFSKEKG 529 Y G +D++L++L+ P+ P+C P K T ++GW ++ Sbjct: 127 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW--ARNGT 184 Query: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589 ++ N L + LV EEC + + +T R C + A G + +H G Sbjct: 185 DLGNSLTTRPVTLVEGEEC-GQVLNVTVTTRTYC---ERSSVAAMHWMDGSVVTREHRGS 240 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 W L G+ + + + TKV+ Y W + + Sbjct: 241 WFLTGVL-GSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >2PKA-B nrPDB Length = 152 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 60/157 (38%), Positives = 89/157 (56%), Gaps = 11/157 (7%) Query: 476 KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEK---GEIQ 532 + +HD+ L++LQ+P T+ K + LP++ + + C +GWG + E Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQ--EPELGSTCEASGWGSIEPGPDDFEFP 59 Query: 533 NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRL 592 + +Q V + L+ N C + D K+T+ M+CAGY GGKD C GDSGGPL+C NGMW Sbjct: 60 DEIQCVQLTLLQNTFCADAHPD-KVTESMLCAGYLPGGKDTCMGDSGGPLIC--NGMW-- 114 Query: 593 VGITSWGE-GCARREQPGVYTKVAEYMDWILEKTQSS 628 GITSWG C +P +YTK+ Y+DWI + + Sbjct: 115 QGITSWGHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >2WIN-I nrPDB Length = 507 Score = 172 bits (437), Expect = 3e-43, Method: Composition-based stats. Identities = 67/281 (23%), Positives = 121/281 (43%), Gaps = 56/281 (19%) Query: 397 SSWGEWPWQVSLQVKLTAQRH-LCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS 455 + + + PWQ + V ++ H C G+++ +VLTAAHCF + ++ G Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG----- 283 Query: 456 DITKDTPFSQIKEIIIHQNYKVSE---------GNHDIALIKLQAPLNYTEFQKPICLP- 505 + +I+ ++ H NY ++ ++D+ALIKL+ L Y + +PICLP Sbjct: 284 ---GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 340 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNI-----------LQKVNIPLVTNEE---CQKR 551 ++G T + T +E Q+I L + + + ++ C++ Sbjct: 341 TEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 400 Query: 552 ------YQDYK-----ITQRMVCAG--YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW 598 Y K +T R +C G + C+GDSGGPL+ + VG+ SW Sbjct: 401 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 460 Query: 599 G-----EGCARREQPGVYTK-----VAEYMDWILEKTQSSD 629 G + R++Q + + + + + W+ EK Q D Sbjct: 461 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 501 >3H7O-A nrPDB Length = 228 Score = 171 bits (434), Expect = 7e-43, Method: Composition-based stats. Identities = 57/236 (24%), Positives = 106/236 (44%), Gaps = 11/236 (4%) Query: 393 GGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGIL 452 GG + + PW V+++ + CGG+++ +VLTAAHC + + Y Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 453 NLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQ-KPICLPSKGDTS 511 D K P+ + + + Y+ +DIA+++L PL + KP LP Sbjct: 62 LWEDPGKSDPY--VSHVYL-SFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRP 118 Query: 512 TIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGK 571 ++ V+G+G + + L+ + +V +EC+ +Y ++ ++ CA ++ G Sbjct: 119 KTGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCA--QKVGV 176 Query: 572 DACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 GD+G P V + LVG+ ++ P V+TKV Y+ WI + + Sbjct: 177 SLESGDAGDPTVQQDT----LVGVAAY-FPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >3H5C-B nrPDB Length = 317 Score = 170 bits (431), Expect = 1e-42, Method: Composition-based stats. Identities = 63/276 (22%), Positives = 108/276 (39%), Gaps = 26/276 (9%) Query: 357 PTRIAYGTQGSSGYSL----RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL 412 P + +Y + GY L + C D C TS + + PWQV L Sbjct: 60 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAP----DLQDLPWQVKL--TN 113 Query: 413 TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIH 472 + + CGG +I +VLT A C + R + + ++D +I + +H Sbjct: 114 SEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPLMIKITHVHVH 167 Query: 473 QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTST---IYTNCWVTGWGFSKEKG 529 Y G +D++L++L+ P+ P+C P K T ++GW ++ Sbjct: 168 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW--ARNGT 225 Query: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589 ++ N L + LV EEC + + +T R C + A G + +H G Sbjct: 226 DLGNSLTTRPVTLVEGEEC-GQVLNVTVTTRTYC---ERSSVAAMHWMDGSVVTREHRGS 281 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625 W L G+ + + + TKV+ Y W + Sbjct: 282 WFLTGVL-GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >1DLE-A nrPDB Length = 298 Score = 167 bits (423), Expect = 1e-41, Method: Composition-based stats. Identities = 67/281 (23%), Positives = 121/281 (43%), Gaps = 56/281 (19%) Query: 397 SSWGEWPWQVSLQVKLTAQRH-LCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS 455 + + + PWQ + V ++ H C G+++ +VLTAAHCF + ++ G Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG----- 76 Query: 456 DITKDTPFSQIKEIIIHQNYKVSE---------GNHDIALIKLQAPLNYTEFQKPICLP- 505 + +I+ ++ H NY ++ ++D+ALIKL+ L Y + +PICLP Sbjct: 77 ---GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 133 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNI-----------LQKVNIPLVTNEE---CQKR 551 ++G T + T +E Q+I L + + + ++ C++ Sbjct: 134 TEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 193 Query: 552 ------YQDYK-----ITQRMVCAG--YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW 598 Y K +T R +C G + C+GDSGGPL+ + VG+ SW Sbjct: 194 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 253 Query: 599 G-----EGCARREQPGVYTK-----VAEYMDWILEKTQSSD 629 G + R++Q + + + + + W+ EK Q D Sbjct: 254 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 294 >3H7T-A nrPDB Length = 235 Score = 167 bits (422), Expect = 2e-41, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 110/251 (43%), Gaps = 22/251 (8%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG S + PW V + V ++ CGGS++ +V+TAA C DG D+ Y Sbjct: 1 IIGGKKSDITKEPWAVGVLVD---EKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS 57 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE-FQKPICLPSKGD 509 TK T K I+ Y ++ A+I+ + P+ + K I LPS Sbjct: 58 SYR---TTKGTSVMAKKIYIV--RYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLY 112 Query: 510 TSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQ----DYKITQRMVCA 564 T+ V+GWG + K E L + N +V + C+++Y+ D I + CA Sbjct: 113 DPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCA 172 Query: 565 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624 G + GD+G P V NG LVG+ S+ E P V+ +V Y+ I + Sbjct: 173 GGEYDETYIGYGDAGDPAV--QNGT--LVGVASYISSMP-SEFPSVFLRVGYYVLDIKDI 227 Query: 625 TQSSDGKAQMQ 635 GK + Q Sbjct: 228 I---SGKVKPQ 235 >5XW8-A nrPDB Length = 133 Score = 166 bits (421), Expect = 3e-41, Method: Composition-based stats. Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 11/143 (7%) Query: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 443 T +IVGG + P+QVSL + H CGGSLI QWV++AAHC+ + Sbjct: 2 PTDDDDKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCY-----KS 52 Query: 444 VWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPIC 503 ++ G N+ + + F +II H N+ + ++DI LIKL +P + Sbjct: 53 RIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 112 Query: 504 LPSKGDTSTIYTNCWVTGWGFSK 526 LP + T C ++GWG +K Sbjct: 113 LPR--SCAAAGTECLISGWGNTK 133 >2OK5-A nrPDB Length = 752 Score = 166 bits (420), Expect = 3e-41, Method: Composition-based stats. Identities = 67/281 (23%), Positives = 121/281 (43%), Gaps = 56/281 (19%) Query: 397 SSWGEWPWQVSLQVKLTAQRH-LCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLS 455 + + + PWQ + V ++ H C G+++ +VLTAAHCF + ++ G Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG----- 527 Query: 456 DITKDTPFSQIKEIIIHQNYKVSE---------GNHDIALIKLQAPLNYTEFQKPICLP- 505 + +I+ ++ H NY ++ ++D+ALIKL+ L Y + +PICLP Sbjct: 528 ---GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC 584 Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNI-----------LQKVNIPLVTNEE---CQKR 551 ++G T + T +E Q+I L + + + ++ C++ Sbjct: 585 TEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 644 Query: 552 ------YQDYK-----ITQRMVCAG--YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW 598 Y K +T R +C G + C+GDSGGPL+ + VG+ SW Sbjct: 645 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 704 Query: 599 G-----EGCARREQPGVYTK-----VAEYMDWILEKTQSSD 629 G + R++Q + + + + + W+ EK Q D Sbjct: 705 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDED 745 >1RIW-B nrPDB Length = 147 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 51/148 (34%), Positives = 76/148 (51%), Gaps = 11/148 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR---- 446 IV G+++ G PWQV L K + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 447 -IYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPIC 503 + G + + ++ S +++I IH Y E + DIAL+KL+ P+ ++++ P+C Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 504 LPSKGDTS---TIYTNCWVTGWGFSKEK 528 LP + + VTGWG KE Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKET 147 >3VGC-B nrPDB Length = 131 Score = 153 bits (386), Expect = 3e-37, Method: Composition-based stats. Identities = 50/136 (36%), Positives = 71/136 (52%), Gaps = 6/136 (4%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G + G WPWQVSLQ K H CGGSLI WV+TAAHC G+ DV + +G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDK--TGFHFCGGSLINENWVVTAAHC--GVTTSDV--VVAG 54 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510 + ++ +I ++ + Y N+DI L+KL ++++ +CLPS D Sbjct: 55 EFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDD 114 Query: 511 STIYTNCWVTGWGFSK 526 T C TGWG ++ Sbjct: 115 FAAGTTCVTTGWGLTR 130 >2JET-B nrPDB Length = 128 Score = 152 bits (384), Expect = 4e-37, Method: Composition-based stats. Identities = 48/133 (36%), Positives = 70/133 (52%), Gaps = 6/133 (4%) Query: 394 GTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILN 453 G ++ G WPWQVSLQ K H CGGSLI WV+TAAHC G+ DV + +G + Sbjct: 1 GEDAIPGSWPWQVSLQDK--TGFHFCGGSLISEDWVVTAAHC--GVKTSDV--VVAGEFD 54 Query: 454 LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTI 513 ++ +I ++ + + + +DI L+KL P ++E +CLP+ D Sbjct: 55 QGSDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPP 114 Query: 514 YTNCWVTGWGFSK 526 T C TGWG +K Sbjct: 115 GTVCATTGWGKTK 127 >1BBR-H nrPDB Length = 150 Score = 151 bits (382), Expect = 7e-37, Method: Composition-based stats. Identities = 50/148 (33%), Positives = 72/148 (48%), Gaps = 11/148 (7%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR---- 446 IV G ++ G PWQV L K + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 447 -IYSGILNLSDITKD-TPFSQIKEIIIHQNYKV-SEGNHDIALIKLQAPLNYTEFQKPIC 503 + G + + + S + +I IH Y + DIAL+KL+ P+ +++ P+C Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 504 LPSKGDTSTI---YTNCWVTGWGFSKEK 528 LP K + + VTGWG +E Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2J8L-A nrPDB Length = 90 Score = 147 bits (372), Expect = 1e-35, Method: Composition-based stats. Identities = 44/87 (50%), Positives = 55/87 (63%) Query: 291 PCHSKIYPGVDFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLR 350 CHS Y DF GEEL++ K CQ+ CT +RCQFFTY+ C E K KC+L+ Sbjct: 1 FCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLK 60 Query: 351 LSMDGSPTRIAYGTQGSSGYSLRLCNT 377 LS +GSPT+I +G G SGY+LRLC Sbjct: 61 LSSNGSPTKILHGRGGISGYTLRLCKM 87 Score = 134 bits (337), Expect = 1e-31, Method: Composition-based stats. Identities = 32/88 (36%), Positives = 42/88 (47%) Query: 111 CHRDIYKGVDMRGVNFNVSKVSSVEECQKRCTNNIRCQFFSYATQTFHKAEYRNNCLLKY 170 CH Y D G ++ S E CQK CTN +RCQFF+Y E + C LK Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKL 61 Query: 171 SPGGTPTAIKVLSNVESGFSLKPCALSE 198 S G+PT I SG++L+ C + Sbjct: 62 SSNGSPTKILHGRGGISGYTLRLCKMDN 89 Score = 126 bits (317), Expect = 3e-29, Method: Composition-based stats. Identities = 24/85 (28%), Positives = 36/85 (42%) Query: 201 CHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLKT 260 CH + + F ++ V C+ +CT C FFT+ + C LK Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKL 61 Query: 261 SESGTPSSSTPQENTISGYSLLTCK 285 S +G+P+ ISGY+L CK Sbjct: 62 SSNGSPTKILHGRGGISGYTLRLCK 86 Score = 118 bits (295), Expect = 1e-26, Method: Composition-based stats. Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Query: 21 CLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFLK 80 C + Y + F G ++ + + + CQ CT RC F++ PA + + E + C+LK Sbjct: 2 CHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCN-EGKGKCYLK 60 Query: 81 DSVTGTLPKV-HRTGAVSGHSLKQC 104 S G+ K+ H G +SG++L+ C Sbjct: 61 LSSNGSPTKILHGRGGISGYTLRLC 85 >2I6S-A nrPDB Length = 517 Score = 141 bits (355), Expect = 1e-33, Method: Composition-based stats. Identities = 65/275 (23%), Positives = 108/275 (39%), Gaps = 58/275 (21%) Query: 403 PWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTP 462 PW V+++ K + C G+LI QWVLTAAHCF +WR+ G ++ Sbjct: 244 PWHVTIKPKS---QETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG----DPKSQWGK 296 Query: 463 FSQIKEIIIHQNYKVSEGNH---------DIALIKLQAPLNYTEFQKPICLP-------- 505 I++ +I + V + DIAL+KL + + +PICLP Sbjct: 297 EFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLA 356 Query: 506 ---SKGDTSTIYTNCWVTGWG----FSKEKGEIQNILQKVNI------PLVTNEECQ-KR 551 +G T + N + F G NI K+ + +V+ E+ Sbjct: 357 LRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPN 416 Query: 552 YQDYK--ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGC----- 602 D + +T + +C+G +E + CKG+SGG + + + VG+ SWG C Sbjct: 417 LTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSAD 475 Query: 603 -------ARREQP---GVYTKVAEYMDWILEKTQS 627 R + P + + W+ + Sbjct: 476 KNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGD 510 >1AKS-B nrPDB Length = 98 Score = 136 bits (343), Expect = 3e-32, Method: Composition-based stats. Identities = 43/103 (41%), Positives = 66/103 (64%), Gaps = 5/103 (4%) Query: 526 KEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK 585 ++LQ + P+++N C+ Y +IT M+C G+ +GGKD+C+GDSGGP+VC Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPG-QITGNMICVGFLQGGKDSCQGDSGGPVVCN 59 Query: 586 HNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 +L GI SWG GCA++ +PGVYTKV Y++WI + ++ Sbjct: 60 G----QLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1BBR-E nrPDB Length = 109 Score = 127 bits (319), Expect = 2e-29, Method: Composition-based stats. Identities = 45/101 (44%), Positives = 56/101 (55%), Gaps = 6/101 (5%) Query: 532 QNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEG---GKDACKGDSGGPLVCK--H 586 ++LQ VN+PLV C+ + +IT M CAGYK G DAC+GDSGGP V K + Sbjct: 7 PSVLQVVNLPLVERPVCKASTR-IRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 587 NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQS 627 N W +GI SWGEGC R + G YT V WI + Sbjct: 66 NNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2HNT-F nrPDB Length = 105 Score = 125 bits (315), Expect = 4e-29, Method: Composition-based stats. Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 6/100 (6%) Query: 532 QNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY--KEGGK-DACKGDSGGPLVCKH-- 586 ++LQ VN+P+V C+ + +IT M CAGY EG + DAC+GDSGGP V K Sbjct: 3 PSVLQVVNLPIVERPVCKDSTR-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 587 NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626 N W +GI SWGEGC R + G YT V WI + Sbjct: 62 NNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVID 101 >2JET-C nrPDB Length = 99 Score = 122 bits (307), Expect = 4e-28, Method: Composition-based stats. Identities = 41/99 (41%), Positives = 60/99 (60%), Gaps = 3/99 (3%) Query: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589 + LQ+ +P+V+ +C+K + KIT M CAG G D+C GDSGGPLVC+ +G+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSW-GSKITDVMTCAGAS--GVDSCMGDSGGPLVCQKDGV 60 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 W L GI SWG G PGVY++V M W+ + +++ Sbjct: 61 WTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILEAN 99 >3RU4-E nrPDB Length = 96 Score = 122 bits (305), Expect = 6e-28, Method: Composition-based stats. Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%) Query: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589 + LQ+ ++PL++N C+K Y KI M+CAG G +C GDSGGPLVCK NG Sbjct: 1 NTPDRLQQASLPLLSNTNCKK-YWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGA 57 Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628 W LVGI SWG PGVY +V ++W+ + ++ Sbjct: 58 WTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN 96 >1EPT-B nrPDB Length = 82 Score = 105 bits (261), Expect = 8e-23, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Query: 443 DVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502 ++ G N+ + + F +II H N+ + ++DI LIKL +P + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 503 CLPSKGDTSTIYTNCWVTGWGFSK 526 LP + T C ++GWG +K Sbjct: 61 SLPR--SCAAAGTECLISGWGNTK 82 >2KAI-A nrPDB Length = 80 Score = 99.3 bits (246), Expect = 5e-21, Method: Composition-based stats. Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 I+GG PWQV++ + Q CGG L+ +WVLTAAHC D + ++ G Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQ---CGGVLVNPKWVLTAAHC-----KNDNYEVWLG 52 Query: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVS 478 NL + F + H + +S Sbjct: 53 RHNLFENENTAQFFGVTADFPHPGFNLS 80 >2HNT-E nrPDB Length = 81 Score = 82.4 bits (202), Expect = 6e-16, Method: Composition-based stats. Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%) Query: 461 TPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKGDTS---TIYTN 516 S +++I IH Y E + DIAL+KL+ P+ ++++ P+CLP + + Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 517 CWVTGWGFSKEK 528 VTGWG KE Sbjct: 63 GRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 78.5 bits (192), Expect = 8e-15, Method: Composition-based stats. Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Query: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450 IV G+++ G PWQV L K + Q LCG SLI +WVLTAAHC P + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 451 ILNLSDITKD 460 ++ + ++ Sbjct: 60 LVRIGKHSRT 69 >1P3E-A nrPDB Length = 215 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 40/111 (36%), Gaps = 5/111 (4%) Query: 413 TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIH 472 T C G+LI +LT HC + S ++D T + + E + Sbjct: 26 TFGGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMTEFYVP 85 Query: 473 QNY-KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGW 522 Y +D A+IK + T + I + T+ T ++G+ Sbjct: 86 SGYINTGASQYDFAVIKTDTNIGNTVGYRSI----RQVTNLTGTTIKISGY 132 >1HKY-A nrPDB Length = 86 Score = 33.5 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 20/32 (62%) Query: 123 GVNFNVSKVSSVEECQKRCTNNIRCQFFSYAT 154 G + +K +S + CQ+ C + +C+FF+ A+ Sbjct: 23 GKAISEAKAASSQACQELCEKDAKCRFFTLAS 54 Score = 31.1 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 299 GVDF-GGEELNVTFVKGVNVCQETCTKMIRCQFFT 332 GV F GG+ ++ CQE C K +C+FFT Sbjct: 17 GVSFTGGKAISEAKAASSQACQELCEKDAKCRFFT 51 >4JCN-A nrPDB Length = 216 Score = 31.1 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 44/120 (36%), Gaps = 13/120 (10%) Query: 407 SLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLP-LQDVWRIYSGILNLSDITKDTPFSQ 465 + + + G ++G +LT H +G ++ N +D Q Sbjct: 24 FIYIPIDGGYMSGSGVVVGENEILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVGQ 83 Query: 466 IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP---SKGDTSTIYTNCWVTGW 522 EII + N D+A++++ P + + + P S + I N VTG+ Sbjct: 84 --EIIPYPG------NSDLAILRVS-PNEHNQHIGQVVKPATISSNTDTRINENITVTGY 134 >5ILB-A nrPDB Length = 474 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 43/140 (30%), Gaps = 38/140 (27%) Query: 395 TNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNL 454 + PWQ K +IG +LT AHC + V R Sbjct: 17 HTAPDYSLPWQ-----KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKR-------- 63 Query: 455 SDITKDTPFSQIKEIIIHQNYKVSEGNHDIALI--------KLQAPLNYT------EFQK 500 + + ++++ + DIAL+ K PL + Sbjct: 64 ----RGDDRKYVAKVLV------RGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVT 113 Query: 501 PICLPSKGDTSTIYTNCWVT 520 + P GDT ++ T V+ Sbjct: 114 VVGYPLGGDTISV-TKGVVS 132 >4FLN-A nrPDB Length = 539 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 43/140 (30%), Gaps = 38/140 (27%) Query: 395 TNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNL 454 + PWQ K +IG +LT AHC + V R Sbjct: 57 HTAPDYSLPWQ-----KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKR-------- 103 Query: 455 SDITKDTPFSQIKEIIIHQNYKVSEGNHDIALI--------KLQAPLNYT------EFQK 500 + + ++++ + DIAL+ K PL + Sbjct: 104 ----RGDDRKYVAKVLV------RGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVT 153 Query: 501 PICLPSKGDTSTIYTNCWVT 520 + P GDT ++ T V+ Sbjct: 154 VVGYPLGGDTISV-TKGVVS 172 >5E5H-A nrPDB Length = 514 Score = 29.6 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 23/56 (41%), Gaps = 1/56 (1%) Query: 432 AAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH-DIAL 486 AAH + ++ G+ +L ++ +I H +Y+ ++ D AL Sbjct: 419 AAHVDHIMQDAQIFVTEQGLADLRGLSPVQRAREIISKCAHPDYRPMLQDYFDRAL 474 >2YIL-A nrPDB Length = 138 Score = 29.6 bits (65), Expect = 4.8, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 289 PEPCHSKIYPGVDFGG--EELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKC 345 P+ S + G E+L+V V C + C + C FTY+ + C + Sbjct: 3 PQLDVSCFAHDKNIGSRTEQLSVVHVASAQDCMKECQALPTCSHFTYNKNSKKCHLKAG 61 >3ISR-A nrPDB Length = 293 Score = 29.2 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 13/29 (44%) Query: 610 VYTKVAEYMDWILEKTQSSDGKAQMQSPA 638 VY+KV DWI + G Q+ A Sbjct: 142 VYSKVLAITDWIYNNVEYISGSTNSQTSA 170 >6H0D-A nrPDB Length = 403 Score = 29.2 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Query: 32 RGGDVASMYTPNAQYCQMRCTFHPRC-LLFS 61 RG ++ + TP+ +Y CT+ PR +LF+ Sbjct: 140 RGHELTFIPTPSPRYPGQLCTYDPRTEILFT 170 >3AK5-A nrPDB Length = 975 Score = 29.2 bits (64), Expect = 5.6, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 11/23 (47%), Gaps = 2/23 (8%) Query: 576 GDSGGPLVCKHN--GMWRLVGIT 596 GDSG PL W LVG+ Sbjct: 205 GDSGSPLFAFDTVQNKWVLVGVL 227 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.138 0.440 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,003,361 Number of Sequences: 36641 Number of extensions: 1162184 Number of successful extensions: 3975 Number of sequences better than 10.0: 182 Number of HSP's better than 10.0 without gapping: 331 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 2202 Number of HSP's gapped (non-prelim): 386 length of query: 638 length of database: 10,336,785 effective HSP length: 103 effective length of query: 535 effective length of database: 6,562,762 effective search space: 3511077670 effective search space used: 3511077670 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 62 (28.4 bits)