BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P03018 (720 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IS4-A nrPDB 1410 0.0 1QHG-A nrPDB 546 e-155 2PJR-A nrPDB 417 e-117 4C2T-A nrPDB 417 e-117 1UAA-A nrPDB 393 e-109 4C2U-A nrPDB 389 e-108 1QHH-B nrPDB 254 1e-67 1QHH-A nrPDB 142 4e-34 1QHH-D nrPDB 138 7e-33 2PJR-B nrPDB 102 5e-22 1QHH-C nrPDB 39 0.008 5Z5I-A nrPDB 33 0.45 5X9Y-C nrPDB 33 0.45 5LJ5-F nrPDB 32 0.89 3F7P-A nrPDB 31 2.0 4Q59-A nrPDB 31 2.1 5LD2-D nrPDB 29 5.7 3DMN-A nrPDB 29 5.7 >2IS4-A nrPDB Length = 680 Score = 1410 bits (3651), Expect = 0.0, Method: Compositional matrix adjust. Identities = 679/680 (99%), Positives = 679/680 (99%) Query: 1 MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAV 60 MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAV Sbjct: 1 MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAV 60 Query: 61 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQL 120 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQL Sbjct: 61 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQL 120 Query: 121 RLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA 180 RLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA Sbjct: 121 RLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA 180 Query: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT Sbjct: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 Query: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN Sbjct: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 Query: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS Sbjct: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 Query: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGD 420 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLI NRNDDAAFERVVNTPTRGIGD Sbjct: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIVNRNDDAAFERVVNTPTRGIGD 420 Query: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ Sbjct: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL Sbjct: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 Query: 541 EAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY 600 EAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY Sbjct: 541 EAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY 600 Query: 601 VGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMG 660 VGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMG Sbjct: 601 VGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMG 660 Query: 661 TPMVENDSGYKLGQRVRHAK 680 TPMVENDSGYKLGQRVRHAK Sbjct: 661 TPMVENDSGYKLGQRVRHAK 680 >1QHG-A nrPDB Length = 724 Score = 546 bits (1407), Expect = e-155, Method: Compositional matrix adjust. Identities = 309/724 (42%), Positives = 455/724 (62%), Gaps = 16/724 (2%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL LN +Q+EAV LL++AGAGSGKTRVL HRIA+LM+ ++ +P++I+A+TFTNK Sbjct: 8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNK 67 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AA EMR R+ L+G + +W+ TFH + R+LR + ++F ILD DQL ++K Sbjct: 68 AAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKT 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-EQTWQKVYQAYQEACDRA 184 ++K N+D K++ PR + I++ K+E L P + E+ VYQ YQ+ R Sbjct: 128 ILKEKNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTYYEKVVSDVYQEYQQRLLRN 187 Query: 185 GLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244 +DF +L++ +L+ P +L +Y+ +F I +DE+QDTN QY ++ LA + Sbjct: 188 HSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDTNRAQYTLVKKLAERFQNIC 247 Query: 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRL 304 VGD DQSIY WRGA ++NI F D+P A+ I LEQNYRST IL AAN +IE+N R Sbjct: 248 AVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRSTKRILQAANEVIEHNVNRK 307 Query: 305 GKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGG-ALAECAILYRSNAQSRVL 363 K++WT+ +G+PI Y A NE DEA+FV RI+ + G + A+LYR+NAQSRV+ Sbjct: 308 PKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGERRYRDFAVLYRTNAQSRVM 367 Query: 364 EEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTL 423 EE LL+A++PY+I GG++F++R+EIKD L+YLR+IAN +DD + R++N P RGIG T+ Sbjct: 368 EEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTI 427 Query: 424 DVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDR 483 D + + + D +L+L++A E L+ L +AA AL F ++ Q + + + Sbjct: 428 DKLVRYAADHELSLFEALGE-LEMIGLGAKAAGALAAFRSQLEQWTQLQEYVSVTELVEE 486 Query: 484 VIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAG 543 V+ SG R M + E+ + Q+R+ENL+E ++ T+ F +D+ L+ AFL+ AL + Sbjct: 487 VLDKSGYREMLKAERTIEAQSRLENLDEFLSVTKHFENVSDDKSLI---AFLTDLALISD 543 Query: 544 EGQADTWQ-----DAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRL 598 + D + DAV LMTLH+AKGLEFP VF++GMEEG+FP SL++ +EEERRL Sbjct: 544 LDELDGTEQAAEGDAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRL 603 Query: 599 AYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEV-RLRATVSRPVSHQ 657 AYVG+TRA ++L LT A+ R L+G PSRF+ E+P +E R +A SRP + Sbjct: 604 AYVGITRAEEELVLTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASRRQAGASRPAVSR 663 Query: 658 RMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQ-GIKWLVAAYAR 716 + V +K+G R H K+G GT+V++ G G+ L +AF GIK L+A +A Sbjct: 664 PQASGAV---GSWKVGDRANHRKWGIGTVVSVRGGGDDQELDIAFPSPIGIKRLLAKFAP 720 Query: 717 LESV 720 +E V Sbjct: 721 IEKV 724 >2PJR-A nrPDB Length = 548 Score = 417 bits (1072), Expect = e-117, Method: Compositional matrix adjust. Identities = 227/537 (42%), Positives = 341/537 (63%), Gaps = 6/537 (1%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL LN +Q+EAV LL++AGAGSGKTRVL HRIA+LM+ ++ +P++I+A+TFTNK Sbjct: 8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNK 67 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AA EMR R+ L+G + +W+ TFH + R+LR + ++F ILD DQL ++K Sbjct: 68 AAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKT 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-EQTWQKVYQAYQEACDRA 184 ++K N+D K++ PR + I++ K+E L P + E+ VYQ YQ+ R Sbjct: 128 ILKEKNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTYYEKVVSDVYQEYQQRLLRN 187 Query: 185 GLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244 +DF +L++ +L+ P +L +Y+ +F I +DE+QDTN QY ++ LA + Sbjct: 188 HSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDTNRAQYTLVKKLAERFQNIC 247 Query: 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRL 304 VGD DQSIY WRGA ++NI F D+P A+ I LEQNYRST IL AAN +IE+N R Sbjct: 248 AVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRSTKRILQAANEVIEHNVNRK 307 Query: 305 GKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGG-ALAECAILYRSNAQSRVL 363 K++WT+ +G+PI Y A NE DEA+FV RI+ + G + A+LYR+NAQSRV+ Sbjct: 308 PKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGERRYRDFAVLYRTNAQSRVM 367 Query: 364 EEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTL 423 EE LL+A++PY+I GG++F++R+EIKD L+YLR+IAN +DD + R++N P RGIG T+ Sbjct: 368 EEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTI 427 Query: 424 DVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDR 483 D + + + D +L+L++A E L+ L +AA AL F ++ Q + + + Sbjct: 428 DKLVRYAADHELSLFEALGE-LEMIGLGAKAAGALAAFRSQLEQWTQLQEYVSVTELVEE 486 Query: 484 VIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 V+ SG R M + E+ + Q+R+ENL+E ++ T+ F +D+ L+ AFL+ AL Sbjct: 487 VLDKSGYREMLKAERTIEAQSRLENLDEFLSVTKHFENVSDDKSLI---AFLTDLAL 540 >4C2T-A nrPDB Length = 745 Score = 417 bits (1072), Expect = e-117, Method: Compositional matrix adjust. Identities = 274/739 (37%), Positives = 402/739 (54%), Gaps = 32/739 (4%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL +LN Q +A LV+AGAGSGKTR L++RIA L+ P I+AVTFTNK Sbjct: 9 LLQALNPTQAQAADHFTGPALVIAGAGSGKTRTLIYRIAHLIGHYGVHPGEILAVTFTNK 68 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AAAEMR R G L+ G +W+ TFH R+LR + L + F I D +DQL ++K Sbjct: 69 AAAEMRERAGHLV-PGAGDLWMSTFHSAGVRILRTYGEHIGLRRGFVIYDDDDQLDIIKE 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-----EQTWQKVYQAYQEA 180 ++ ++ + PR I+ K P + P + Y+ Y+ Sbjct: 128 VMGSIPGIGAETQPRVIRGIIDRAKSNLWTPDDLDRSREPFISGLPRDAAAEAYRRYEVR 187 Query: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 +DF +L+ L+ P +L + + I VDE+QDTN QY RLLA Sbjct: 188 KKGQNAIDFGDLITETVRLFKEVPGVLDKVQNKAKFIHVDEYQDTNRAQYELTRLLASRD 247 Query: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 +++VGD DQSIY +RGA ++NI F D+P A+ LE NYRS++ +L AAN LIENN Sbjct: 248 RNLLVVGDPDQSIYKFRGADIQNILDFQKDYPDAKVYMLEHNYRSSARVLEAANKLIENN 307 Query: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 RL K L G+P++ + A + E +V + + G A +E AILYR+NAQS Sbjct: 308 TERLDKTLKPVKEAGQPVTFHRATDHRAEGDYVADWLTRLHGEGRAWSEMAILYRTNAQS 367 Query: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGD 420 RV+EE+L + +P RI GG+ F++R+EI+D L+Y RL N DD A R++ P RGIGD Sbjct: 368 RVIEESLRRVQIPARIVGGVGFYDRREIRDILAYARLALNPADDVALRRIIGRPRRGIGD 427 Query: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 L + + +R ++ AC ++ L R A F L++A+++ + Sbjct: 428 TALQKLMEWARTHHTSVLTACANAAEQNIL-DRGAHKATEFAGLMEAMSEAADNYEPAAF 486 Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 V++ SG + QE G++GQ R+ENLEELV+A ++S +E + + FL AAL Sbjct: 487 LRFVMETSGYLDLLRQE-GQEGQVRLENLEELVSAAEEWSQDEANVG-GSIADFLDDAAL 544 Query: 541 EAGEGQADTW-------QDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGR-L 592 + T +DAV LMTLH+AKGLEFP VFIVG+E+G+ PS+ ++ EG + Sbjct: 545 LSSVDDMRTKAENKGAPEDAVTLMTLHNAKGLEFPVVFIVGVEQGLLPSKGAIAEGPSGI 604 Query: 593 EEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGEL------------PEEC 640 EEERRL YVG+TRAM++L +T A+ R +GK S F+ ++ P E Sbjct: 605 EEERRLFYVGITRAMERLLMTAAQNRMQFGKTNAAEDSAFLEDIEGLFDTVDPYGQPIEY 664 Query: 641 VEEV--RLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRL 698 + + R TV + + +P+ + Y+ G++V+H KFGEG ++ + G GE + Sbjct: 665 RAKTWKQYRPTVPAATTAVKNTSPLTA-ELAYRGGEQVKHPKFGEGQVLAVAGVGERQEV 723 Query: 699 QVAFQGQGIKWLVAAYARL 717 V F G K L+ +A L Sbjct: 724 TVHFASAGTKKLMVKFANL 742 >1UAA-A nrPDB Length = 673 Score = 393 bits (1010), Expect = e-109, Method: Compositional matrix adjust. Identities = 246/641 (38%), Positives = 362/641 (56%), Gaps = 18/641 (2%) Query: 10 LNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNKAAAE 69 LN Q++AV LVLAGAGSGKTRV+ ++IA L+ I AVTFTNKAA E Sbjct: 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 70 MRHRIGQLMGTSQG-GMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIK 128 M+ R+GQ +G + G+ + TFH L +++ + + +F + D DQL LLK L + Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTE 122 Query: 129 AMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYG----NPVEQTWQKVYQAYQEACDRA 184 + D+K +Q + I++ K++ P + + + +Y A+ +AC+ Sbjct: 123 GLIEDDKVLL-QQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACN-- 179 Query: 185 GLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244 ++DF +L+L L + + ++ + +LVDE+QDTN QY ++LL G + Sbjct: 180 -VLDFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFT 238 Query: 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRL 304 +VGDDDQSIY WRGA+ +N+ DFP + I+LEQNYRS+ IL AAN LI NN Sbjct: 239 VVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVF 298 Query: 305 GKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQ-DNGGALAECAILYRSNAQSRVL 363 K+L+++ G + + A NE EA V + N + AILYR N QSRV Sbjct: 299 EKRLFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVF 358 Query: 364 EEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTL 423 E+ L+Q +PY+I GG FF R EIKD L+YLR++ N +DD+AF R+VNTP R IG TL Sbjct: 359 EKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATL 418 Query: 424 DVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDR 483 + + + R +++ A ++ + L+GR AL RF + + + P+ D Sbjct: 419 KKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEIQRLAEREPIAAVRDL 478 Query: 484 VIKDSGLRTMYEQEKGEK-GQTRIENLEELVT-ATRQFSYNEEDEDLMPLQA---FLSHA 538 + +YE K + R++N+ +L + T +E DE + Q F Sbjct: 479 IHGMDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRD 538 Query: 539 ALEAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRL 598 +E GE + + D VQLMTLH++KGLEFP V++VGMEEG P Q S+DE ++EERRL Sbjct: 539 MMERGESEEEL--DQVQLMTLHASKGLEFPYVYMVGMEEGFLPHQSSIDEDN-IDEERRL 595 Query: 599 AYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEE 639 AYVG+TRA ++LT T + RR YG+ V PSRF+ ELP++ Sbjct: 596 AYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQD 636 >4C2U-A nrPDB Length = 665 Score = 389 bits (998), Expect = e-108, Method: Compositional matrix adjust. Identities = 249/644 (38%), Positives = 360/644 (55%), Gaps = 17/644 (2%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL +LN Q +A LV+AGAGSGKTR L++RIA L+ P I+AVTFTNK Sbjct: 9 LLQALNPTQAQAADHFTGPALVIAGAGSGKTRTLIYRIAHLIGHYGVHPGEILAVTFTNK 68 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AAAEMR R G L+ G +W+ TFH R+LR + L + F I D +DQL ++K Sbjct: 69 AAAEMRERAGHLV-PGAGDLWMSTFHSAGVRILRTYGEHIGLRRGFVIYDDDDQLDIIKE 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-----EQTWQKVYQAYQEA 180 ++ ++ + PR I+ K P + P + Y+ Y+ Sbjct: 128 VMGSIPGIGAETQPRVIRGIIDRAKSNLWTPDDLDRSREPFISGLPRDAAAEAYRRYEVR 187 Query: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 +DF +L+ L+ P +L + + I VDE+QDTN QY RLLA Sbjct: 188 KKGQNAIDFGDLITETVRLFKEVPGVLDKVQNKAKFIHVDEYQDTNRAQYELTRLLASRD 247 Query: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 +++VGD DQSIY +RGA ++NI F D+P A+ LE NYRS++ +L AAN LIENN Sbjct: 248 RNLLVVGDPDQSIYKFRGADIQNILDFQKDYPDAKVYMLEHNYRSSARVLEAANKLIENN 307 Query: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 RL K L G+P++ + A + E +V + + G A +E AILYR+NAQS Sbjct: 308 TERLDKTLKPVKEAGQPVTFHRATDHRAEGDYVADWLTRLHGEGRAWSEMAILYRTNAQS 367 Query: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGD 420 RV+EE+L + +P RI GG+ F++R+EI+D L+Y RL N DD A R++ P RGIGD Sbjct: 368 RVIEESLRRVQIPARIVGGVGFYDRREIRDILAYARLALNPADDVALRRIIGRPRRGIGD 427 Query: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 L + + +R ++ AC ++ L R A F L++A+++ + Sbjct: 428 TALQKLMEWARTHHTSVLTACANAAEQNIL-DRGAHKATEFAGLMEAMSEAADNYEPAAF 486 Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 V++ SG + QE G++GQ R+ENLEELV+A ++S +E + + FL AAL Sbjct: 487 LRFVMETSGYLDLLRQE-GQEGQVRLENLEELVSAAEEWSQDEANVG-GSIADFLDDAAL 544 Query: 541 EAGEGQADTW-------QDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGR-L 592 + T +DAV LMTLH+AKGLEFP VFIVG+E+G+ PS+ ++ EG + Sbjct: 545 LSSVDDMRTKAENKGAPEDAVTLMTLHNAKGLEFPVVFIVGVEQGLLPSKGAIAEGPSGI 604 Query: 593 EEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGEL 636 EEERRL YVG+TRAM++L +T A+ R +GK S F+ ++ Sbjct: 605 EEERRLFYVGITRAMERLLMTAAQNRMQFGKTNAAEDSAFLEDI 648 >1QHH-B nrPDB Length = 273 Score = 254 bits (648), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 126/271 (46%), Positives = 182/271 (67%), Gaps = 1/271 (0%) Query: 167 EQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTN 226 E+ VYQ YQ+ R +DF +L++ +L+ P +L +Y+ +F I +DE+QDTN Sbjct: 3 EKVVSDVYQEYQQRLLRNHSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDTN 62 Query: 227 NIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRST 286 QY ++ LA + VGD DQSIY WRGA ++NI F D+P A+ I LEQNYRST Sbjct: 63 RAQYTLVKKLAERFQNICAVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRST 122 Query: 287 SNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGG- 345 IL AAN +IE+N R K++WT+ +G+PI Y A NE DEA+FV RI+ + G Sbjct: 123 KRILQAANEVIEHNVNRKPKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGER 182 Query: 346 ALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDA 405 + A+LYR+NAQSRV+EE LL+A++PY+I GG++F++R+EIKD L+YLR+IAN +DD Sbjct: 183 RYRDFAVLYRTNAQSRVMEEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDL 242 Query: 406 AFERVVNTPTRGIGDRTLDVVRQTSRDRQLT 436 + R++N P RGIG T+D + + + D +L+ Sbjct: 243 SLLRIINVPKRGIGASTIDKLVRYAADHELS 273 >1QHH-A nrPDB Length = 167 Score = 142 bits (359), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 69/151 (45%), Positives = 103/151 (68%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL LN +Q+EAV LL++AGAGSGKTRVL HRIA+LM+ ++ +P++I+A+TFTNK Sbjct: 8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNK 67 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AA EMR R+ L+G + +W+ TFH + R+LR + ++F ILD DQL ++K Sbjct: 68 AAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKT 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRP 156 ++K N+D K++ PR + I++ K+E L P Sbjct: 128 ILKEKNIDPKKFEPRTILGTISAAKNELLPP 158 >1QHH-D nrPDB Length = 169 Score = 138 bits (348), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 81/171 (47%), Positives = 111/171 (64%), Gaps = 5/171 (2%) Query: 552 DAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLT 611 DAV LMTLH+AKGLEFP VF++GMEEG+FP SL++ +EEERRLAYVG+TRA ++L Sbjct: 2 DAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRLAYVGITRAEEELV 61 Query: 612 LTYAETRRLYGKEVYHRPSRFIGELPEECVEEV-RLRATVSRPVSHQRMGTPMVENDSGY 670 LT A+ R L+G PSRF+ E+P +E R +A SRP + + V + + Sbjct: 62 LTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASRRQAGASRPAVSRPQASGAVGS---W 118 Query: 671 KLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQ-GIKWLVAAYARLESV 720 K+G R H K+G GT+V++ G G+ L +AF GIK L+A +A +E V Sbjct: 119 KVGDRANHRKWGIGTVVSVRGGGDDQELDIAFPSPIGIKRLLAKFAPIEKV 169 >2PJR-B nrPDB Length = 95 Score = 102 bits (255), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 53/91 (58%), Positives = 68/91 (74%) Query: 552 DAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLT 611 DAV LMTLH+AKGLEFP VF++GMEEG+FP SL++ +EEERRLAYVG+TRA ++L Sbjct: 2 DAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRLAYVGITRAEEELV 61 Query: 612 LTYAETRRLYGKEVYHRPSRFIGELPEECVE 642 LT A+ R L+G PSRF+ E+P +E Sbjct: 62 LTSAQMRTLFGNIQMDPPSRFLNEIPAHLLE 92 >1QHH-C nrPDB Length = 115 Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 36/60 (60%), Gaps = 3/60 (5%) Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 + V+ SG R M + E+ + Q+R+ENL+E ++ T+ F +D+ L+ AFL+ AL Sbjct: 44 VEEVLDKSGYREMLKAERTIEAQSRLENLDEFLSVTKHFENVSDDKSLI---AFLTDLAL 100 >5Z5I-A nrPDB Length = 543 Score = 33.1 bits (74), Expect = 0.45, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 33/69 (47%) Query: 295 ALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILY 354 +L +N+G++ D A GE + +Y A +L + + R W+ GG+ E LY Sbjct: 123 SLFFDNDGKVYITGTNDNARGEELGIYQAEIDLKKGSIIGERKLIWKGTGGSYPEAPHLY 182 Query: 355 RSNAQSRVL 363 + N +L Sbjct: 183 KVNGWYYLL 191 >5X9Y-C nrPDB Length = 308 Score = 33.1 bits (74), Expect = 0.45, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 7/76 (9%) Query: 46 LMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDA 105 L S+ + S + + + F K E+ G ++GT + GM VGT + + Sbjct: 92 LYSISSVSKFKLRSRFFQEKEGKEIEVEAGNILGTRRVGMPVGT-------EVEVRDLFF 144 Query: 106 NLPQDFQILDSEDQLR 121 NLP + L ED R Sbjct: 145 NLPVRRKFLKKEDTER 160 >5LJ5-F nrPDB Length = 179 Score = 32.0 bits (71), Expect = 0.89, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 32/62 (51%) Query: 437 LWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQ 496 +W+ ++L+ E+ +++ EL + L + + D P ++ D +K SGL MY+ Sbjct: 23 VWETEQDLITEQQKLNTRLKEIEKERELNELLNESSKDKPETLKNDLALKKSGLEWMYQD 82 Query: 497 EK 498 K Sbjct: 83 AK 84 >3F7P-A nrPDB Length = 296 Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust. Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 6/49 (12%) Query: 363 LEEALLQASMPYRIYGGMRFFERQEIKDALSYLR-----LIANRNDDAA 406 L E L S+P R G MRF + Q ++ AL YLR L+ RNDD A Sbjct: 109 LLEVLSGDSLP-REKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIA 156 >4Q59-A nrPDB Length = 226 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 6/49 (12%) Query: 363 LEEALLQASMPYRIYGGMRFFERQEIKDALSYLR-----LIANRNDDAA 406 L E L S+P R G MRF + Q ++ AL YLR L+ RNDD A Sbjct: 42 LLEVLSGDSLP-REKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIA 89 >5LD2-D nrPDB Length = 609 Score = 29.3 bits (64), Expect = 5.7, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 13/64 (20%) Query: 557 MTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAE 616 MT+H ++G EF ++ PSQ + R L Y VTRA ++L+L YA+ Sbjct: 537 MTVHKSQGSEFDHAALI------LPSQRTP------VVTRELVYTAVTRARRRLSL-YAD 583 Query: 617 TRRL 620 R L Sbjct: 584 ERIL 587 >3DMN-A nrPDB Length = 174 Score = 29.3 bits (64), Expect = 5.7, Method: Compositional matrix adjust. Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 10/51 (19%) Query: 562 AKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTL 612 AKGLEF V + + E + E+ER+L Y +RAM +LTL Sbjct: 110 AKGLEFDAVIVWNANQ----------ENYQREDERQLLYTICSRAMHELTL 150 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2IS4-A nrPDB 1074 0.0 1QHG-A nrPDB 1067 0.0 4C2T-A nrPDB 995 0.0 4C2U-A nrPDB 899 0.0 1UAA-A nrPDB 840 0.0 2PJR-A nrPDB 817 0.0 1QHH-B nrPDB 456 e-128 1QHH-A nrPDB 267 1e-71 1QHH-D nrPDB 260 1e-69 2PJR-B nrPDB 152 4e-37 Sequences not found previously or not previously below threshold: 1QHH-C nrPDB 110 2e-24 6MBJ-A nrPDB 46 6e-05 5LD2-D nrPDB 36 0.074 5CA8-A nrPDB 35 0.11 1G71-A nrPDB 34 0.19 6FYX-o nrPDB 33 0.51 3SQW-A nrPDB 33 0.56 3DMN-A nrPDB 32 0.69 6HIX-AE nrPDB 32 1.0 2JGD-B nrPDB 32 1.0 1K0R-A nrPDB 32 1.2 6AGH-A nrPDB 31 1.5 5Z5I-A nrPDB 31 1.5 5LJ5-F nrPDB 31 2.3 2DVL-A nrPDB 30 2.8 >2IS4-A nrPDB Length = 680 Score = 1074 bits (2778), Expect = 0.0, Method: Composition-based stats. Identities = 679/680 (99%), Positives = 679/680 (99%) Query: 1 MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAV 60 MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAV Sbjct: 1 MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAV 60 Query: 61 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQL 120 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQL Sbjct: 61 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQL 120 Query: 121 RLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA 180 RLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA Sbjct: 121 RLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA 180 Query: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT Sbjct: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 Query: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN Sbjct: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 Query: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS Sbjct: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 Query: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGD 420 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLI NRNDDAAFERVVNTPTRGIGD Sbjct: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIVNRNDDAAFERVVNTPTRGIGD 420 Query: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ Sbjct: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL Sbjct: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 Query: 541 EAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY 600 EAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY Sbjct: 541 EAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY 600 Query: 601 VGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMG 660 VGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMG Sbjct: 601 VGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMG 660 Query: 661 TPMVENDSGYKLGQRVRHAK 680 TPMVENDSGYKLGQRVRHAK Sbjct: 661 TPMVENDSGYKLGQRVRHAK 680 >1QHG-A nrPDB Length = 724 Score = 1067 bits (2760), Expect = 0.0, Method: Composition-based stats. Identities = 309/724 (42%), Positives = 455/724 (62%), Gaps = 16/724 (2%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL LN +Q+EAV LL++AGAGSGKTRVL HRIA+LM+ ++ +P++I+A+TFTNK Sbjct: 8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNK 67 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AA EMR R+ L+G + +W+ TFH + R+LR + ++F ILD DQL ++K Sbjct: 68 AAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKT 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-EQTWQKVYQAYQEACDRA 184 ++K N+D K++ PR + I++ K+E L P + E+ VYQ YQ+ R Sbjct: 128 ILKEKNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTYYEKVVSDVYQEYQQRLLRN 187 Query: 185 GLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244 +DF +L++ +L+ P +L +Y+ +F I +DE+QDTN QY ++ LA + Sbjct: 188 HSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDTNRAQYTLVKKLAERFQNIC 247 Query: 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRL 304 VGD DQSIY WRGA ++NI F D+P A+ I LEQNYRST IL AAN +IE+N R Sbjct: 248 AVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRSTKRILQAANEVIEHNVNRK 307 Query: 305 GKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNG-GALAECAILYRSNAQSRVL 363 K++WT+ +G+PI Y A NE DEA+FV RI+ + G + A+LYR+NAQSRV+ Sbjct: 308 PKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGERRYRDFAVLYRTNAQSRVM 367 Query: 364 EEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTL 423 EE LL+A++PY+I GG++F++R+EIKD L+YLR+IAN +DD + R++N P RGIG T+ Sbjct: 368 EEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTI 427 Query: 424 DVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDR 483 D + + + D +L+L++A E L+ L +AA AL F ++ Q + + + Sbjct: 428 DKLVRYAADHELSLFEALGE-LEMIGLGAKAAGALAAFRSQLEQWTQLQEYVSVTELVEE 486 Query: 484 VIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAG 543 V+ SG R M + E+ + Q+R+ENL+E ++ T+ F +D+ L+ AFL+ AL + Sbjct: 487 VLDKSGYREMLKAERTIEAQSRLENLDEFLSVTKHFENVSDDKSLI---AFLTDLALISD 543 Query: 544 EGQADTWQ-----DAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRL 598 + D + DAV LMTLH+AKGLEFP VF++GMEEG+FP SL++ +EEERRL Sbjct: 544 LDELDGTEQAAEGDAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRL 603 Query: 599 AYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEV-RLRATVSRPVSHQ 657 AYVG+TRA ++L LT A+ R L+G PSRF+ E+P +E R +A SRP + Sbjct: 604 AYVGITRAEEELVLTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASRRQAGASRPAVSR 663 Query: 658 RMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQ-GIKWLVAAYAR 716 + V +K+G R H K+G GT+V++ G G+ L +AF GIK L+A +A Sbjct: 664 PQASGAVG---SWKVGDRANHRKWGIGTVVSVRGGGDDQELDIAFPSPIGIKRLLAKFAP 720 Query: 717 LESV 720 +E V Sbjct: 721 IEKV 724 >4C2T-A nrPDB Length = 745 Score = 995 bits (2573), Expect = 0.0, Method: Composition-based stats. Identities = 274/742 (36%), Positives = 403/742 (54%), Gaps = 32/742 (4%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL +LN Q +A LV+AGAGSGKTR L++RIA L+ P I+AVTFTNK Sbjct: 9 LLQALNPTQAQAADHFTGPALVIAGAGSGKTRTLIYRIAHLIGHYGVHPGEILAVTFTNK 68 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AAAEMR R G L+ G +W+ TFH R+LR + L + F I D +DQL ++K Sbjct: 69 AAAEMRERAGHLV-PGAGDLWMSTFHSAGVRILRTYGEHIGLRRGFVIYDDDDQLDIIKE 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-----EQTWQKVYQAYQEA 180 ++ ++ + PR I+ K P + P + Y+ Y+ Sbjct: 128 VMGSIPGIGAETQPRVIRGIIDRAKSNLWTPDDLDRSREPFISGLPRDAAAEAYRRYEVR 187 Query: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 +DF +L+ L+ P +L + + I VDE+QDTN QY RLLA Sbjct: 188 KKGQNAIDFGDLITETVRLFKEVPGVLDKVQNKAKFIHVDEYQDTNRAQYELTRLLASRD 247 Query: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 +++VGD DQSIY +RGA ++NI F D+P A+ LE NYRS++ +L AAN LIENN Sbjct: 248 RNLLVVGDPDQSIYKFRGADIQNILDFQKDYPDAKVYMLEHNYRSSARVLEAANKLIENN 307 Query: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 RL K L G+P++ + A + E +V + + G A +E AILYR+NAQS Sbjct: 308 TERLDKTLKPVKEAGQPVTFHRATDHRAEGDYVADWLTRLHGEGRAWSEMAILYRTNAQS 367 Query: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGD 420 RV+EE+L + +P RI GG+ F++R+EI+D L+Y RL N DD A R++ P RGIGD Sbjct: 368 RVIEESLRRVQIPARIVGGVGFYDRREIRDILAYARLALNPADDVALRRIIGRPRRGIGD 427 Query: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 L + + +R ++ AC ++ L R A F L++A+++ + Sbjct: 428 TALQKLMEWARTHHTSVLTACANAAEQNIL-DRGAHKATEFAGLMEAMSEAADNYEPAAF 486 Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 V++ SG + QE G++GQ R+ENLEELV+A ++S +E + + FL AAL Sbjct: 487 LRFVMETSGYLDLLRQE-GQEGQVRLENLEELVSAAEEWSQDEANVG-GSIADFLDDAAL 544 Query: 541 EAGEGQADTW-------QDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGR-L 592 + T +DAV LMTLH+AKGLEFP VFIVG+E+G+ PS+ ++ EG + Sbjct: 545 LSSVDDMRTKAENKGAPEDAVTLMTLHNAKGLEFPVVFIVGVEQGLLPSKGAIAEGPSGI 604 Query: 593 EEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGEL------------PEEC 640 EEERRL YVG+TRAM++L +T A+ R +GK S F+ ++ P E Sbjct: 605 EEERRLFYVGITRAMERLLMTAAQNRMQFGKTNAAEDSAFLEDIEGLFDTVDPYGQPIEY 664 Query: 641 VEEV--RLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRL 698 + + R TV + + +P+ + Y+ G++V+H KFGEG ++ + G GE + Sbjct: 665 RAKTWKQYRPTVPAATTAVKNTSPLTA-ELAYRGGEQVKHPKFGEGQVLAVAGVGERQEV 723 Query: 699 QVAFQGQGIKWLVAAYARLESV 720 V F G K L+ +A L + Sbjct: 724 TVHFASAGTKKLMVKFANLTKL 745 >4C2U-A nrPDB Length = 665 Score = 899 bits (2323), Expect = 0.0, Method: Composition-based stats. Identities = 249/644 (38%), Positives = 360/644 (55%), Gaps = 17/644 (2%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL +LN Q +A LV+AGAGSGKTR L++RIA L+ P I+AVTFTNK Sbjct: 9 LLQALNPTQAQAADHFTGPALVIAGAGSGKTRTLIYRIAHLIGHYGVHPGEILAVTFTNK 68 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AAAEMR R G L+ G +W+ TFH R+LR + L + F I D +DQL ++K Sbjct: 69 AAAEMRERAGHLV-PGAGDLWMSTFHSAGVRILRTYGEHIGLRRGFVIYDDDDQLDIIKE 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-----EQTWQKVYQAYQEA 180 ++ ++ + PR I+ K P + P + Y+ Y+ Sbjct: 128 VMGSIPGIGAETQPRVIRGIIDRAKSNLWTPDDLDRSREPFISGLPRDAAAEAYRRYEVR 187 Query: 181 CDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240 +DF +L+ L+ P +L + + I VDE+QDTN QY RLLA Sbjct: 188 KKGQNAIDFGDLITETVRLFKEVPGVLDKVQNKAKFIHVDEYQDTNRAQYELTRLLASRD 247 Query: 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENN 300 +++VGD DQSIY +RGA ++NI F D+P A+ LE NYRS++ +L AAN LIENN Sbjct: 248 RNLLVVGDPDQSIYKFRGADIQNILDFQKDYPDAKVYMLEHNYRSSARVLEAANKLIENN 307 Query: 301 NGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQS 360 RL K L G+P++ + A + E +V + + G A +E AILYR+NAQS Sbjct: 308 TERLDKTLKPVKEAGQPVTFHRATDHRAEGDYVADWLTRLHGEGRAWSEMAILYRTNAQS 367 Query: 361 RVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGD 420 RV+EE+L + +P RI GG+ F++R+EI+D L+Y RL N DD A R++ P RGIGD Sbjct: 368 RVIEESLRRVQIPARIVGGVGFYDRREIRDILAYARLALNPADDVALRRIIGRPRRGIGD 427 Query: 421 RTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQ 480 L + + +R ++ AC ++ L R A F L++A+++ + Sbjct: 428 TALQKLMEWARTHHTSVLTACANAAEQNIL-DRGAHKATEFAGLMEAMSEAADNYEPAAF 486 Query: 481 TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL 540 V++ SG + QE G++GQ R+ENLEELV+A ++S +E + + FL AAL Sbjct: 487 LRFVMETSGYLDLLRQE-GQEGQVRLENLEELVSAAEEWSQDEANVG-GSIADFLDDAAL 544 Query: 541 EAGEGQADTW-------QDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGR-L 592 + T +DAV LMTLH+AKGLEFP VFIVG+E+G+ PS+ ++ EG + Sbjct: 545 LSSVDDMRTKAENKGAPEDAVTLMTLHNAKGLEFPVVFIVGVEQGLLPSKGAIAEGPSGI 604 Query: 593 EEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGEL 636 EEERRL YVG+TRAM++L +T A+ R +GK S F+ ++ Sbjct: 605 EEERRLFYVGITRAMERLLMTAAQNRMQFGKTNAAEDSAFLEDI 648 >1UAA-A nrPDB Length = 673 Score = 840 bits (2169), Expect = 0.0, Method: Composition-based stats. Identities = 250/663 (37%), Positives = 369/663 (55%), Gaps = 18/663 (2%) Query: 10 LNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNKAAAE 69 LN Q++AV LVLAGAGSGKTRV+ ++IA L+ I AVTFTNKAA E Sbjct: 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 70 MRHRIGQLMGTSQG-GMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIK 128 M+ R+GQ +G + G+ + TFH L +++ + + +F + D DQL LLK L + Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTE 122 Query: 129 AMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYG----NPVEQTWQKVYQAYQEACDRA 184 + D+K +Q + I++ K++ P + + + +Y A+ +AC Sbjct: 123 GLIEDDKVLL-QQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKAC--- 178 Query: 185 GLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244 ++DF +L+L L + + ++ + +LVDE+QDTN QY ++LL G + Sbjct: 179 NVLDFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFT 238 Query: 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRL 304 +VGDDDQSIY WRGA+ +N+ DFP + I+LEQNYRS+ IL AAN LI NN Sbjct: 239 VVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVF 298 Query: 305 GKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQ-DNGGALAECAILYRSNAQSRVL 363 K+L+++ G + + A NE EA V + N + AILYR N QSRV Sbjct: 299 EKRLFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVF 358 Query: 364 EEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTL 423 E+ L+Q +PY+I GG FF R EIKD L+YLR++ N +DD+AF R+VNTP R IG TL Sbjct: 359 EKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATL 418 Query: 424 DVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDR 483 + + + R +++ A ++ + L+GR AL RF + + + P+ D Sbjct: 419 KKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEIQRLAEREPIAAVRDL 478 Query: 484 VIKDSGLRTMYEQEKGEK-GQTRIENLEELVT-ATRQFSYNEEDEDLMPLQA---FLSHA 538 + +YE K + R++N+ +L + T +E DE + Q F Sbjct: 479 IHGMDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRD 538 Query: 539 ALEAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRL 598 +E GE + + D VQLMTLH++KGLEFP V++VGMEEG P Q S+DE ++EERRL Sbjct: 539 MMERGESEEEL--DQVQLMTLHASKGLEFPYVYMVGMEEGFLPHQSSIDEDN-IDEERRL 595 Query: 599 AYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQR 658 AYVG+TRA ++LT T + RR YG+ V PSRF+ ELP++ + + R VS Q+ Sbjct: 596 AYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIWEQERKVVSAEERMQK 655 Query: 659 MGT 661 + Sbjct: 656 GQS 658 >2PJR-A nrPDB Length = 548 Score = 817 bits (2109), Expect = 0.0, Method: Composition-based stats. Identities = 228/545 (41%), Positives = 344/545 (63%), Gaps = 6/545 (1%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL LN +Q+EAV LL++AGAGSGKTRVL HRIA+LM+ ++ +P++I+A+TFTNK Sbjct: 8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNK 67 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AA EMR R+ L+G + +W+ TFH + R+LR + ++F ILD DQL ++K Sbjct: 68 AAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKT 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPV-EQTWQKVYQAYQEACDRA 184 ++K N+D K++ PR + I++ K+E L P + E+ VYQ YQ+ R Sbjct: 128 ILKEKNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTYYEKVVSDVYQEYQQRLLRN 187 Query: 185 GLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244 +DF +L++ +L+ P +L +Y+ +F I +DE+QDTN QY ++ LA + Sbjct: 188 HSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDTNRAQYTLVKKLAERFQNIC 247 Query: 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRL 304 VGD DQSIY WRGA ++NI F D+P A+ I LEQNYRST IL AAN +IE+N R Sbjct: 248 AVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRSTKRILQAANEVIEHNVNRK 307 Query: 305 GKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNG-GALAECAILYRSNAQSRVL 363 K++WT+ +G+PI Y A NE DEA+FV RI+ + G + A+LYR+NAQSRV+ Sbjct: 308 PKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGERRYRDFAVLYRTNAQSRVM 367 Query: 364 EEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTL 423 EE LL+A++PY+I GG++F++R+EIKD L+YLR+IAN +DD + R++N P RGIG T+ Sbjct: 368 EEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTI 427 Query: 424 DVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDR 483 D + + + D +L+L++A E L+ L +AA AL F ++ Q + + + Sbjct: 428 DKLVRYAADHELSLFEALGE-LEMIGLGAKAAGALAAFRSQLEQWTQLQEYVSVTELVEE 486 Query: 484 VIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAG 543 V+ SG R M + E+ + Q+R+ENL+E ++ T+ F +D+ L+ AFL+ AL + Sbjct: 487 VLDKSGYREMLKAERTIEAQSRLENLDEFLSVTKHFENVSDDKSLI---AFLTDLALISD 543 Query: 544 EGQAD 548 + D Sbjct: 544 LDELD 548 >1QHH-B nrPDB Length = 273 Score = 456 bits (1173), Expect = e-128, Method: Composition-based stats. Identities = 126/272 (46%), Positives = 182/272 (66%), Gaps = 1/272 (0%) Query: 166 VEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDT 225 E+ VYQ YQ+ R +DF +L++ +L+ P +L +Y+ +F I +DE+QDT Sbjct: 2 YEKVVSDVYQEYQQRLLRNHSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDT 61 Query: 226 NNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRS 285 N QY ++ LA + VGD DQSIY WRGA ++NI F D+P A+ I LEQNYRS Sbjct: 62 NRAQYTLVKKLAERFQNICAVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRS 121 Query: 286 TSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNG- 344 T IL AAN +IE+N R K++WT+ +G+PI Y A NE DEA+FV RI+ + G Sbjct: 122 TKRILQAANEVIEHNVNRKPKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGE 181 Query: 345 GALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDD 404 + A+LYR+NAQSRV+EE LL+A++PY+I GG++F++R+EIKD L+YLR+IAN +DD Sbjct: 182 RRYRDFAVLYRTNAQSRVMEEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDD 241 Query: 405 AAFERVVNTPTRGIGDRTLDVVRQTSRDRQLT 436 + R++N P RGIG T+D + + + D +L+ Sbjct: 242 LSLLRIINVPKRGIGASTIDKLVRYAADHELS 273 >1QHH-A nrPDB Length = 167 Score = 267 bits (682), Expect = 1e-71, Method: Composition-based stats. Identities = 69/160 (43%), Positives = 104/160 (65%) Query: 6 LLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNK 65 LL LN +Q+EAV LL++AGAGSGKTRVL HRIA+LM+ ++ +P++I+A+TFTNK Sbjct: 8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNK 67 Query: 66 AAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKR 125 AA EMR R+ L+G + +W+ TFH + R+LR + ++F ILD DQL ++K Sbjct: 68 AAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKT 127 Query: 126 LIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNP 165 ++K N+D K++ PR + I++ K+E L P + Sbjct: 128 ILKEKNIDPKKFEPRTILGTISAAKNELLPPEQFAKRAST 167 >1QHH-D nrPDB Length = 169 Score = 260 bits (664), Expect = 1e-69, Method: Composition-based stats. Identities = 81/171 (47%), Positives = 110/171 (64%), Gaps = 5/171 (2%) Query: 552 DAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLT 611 DAV LMTLH+AKGLEFP VF++GMEEG+FP SL++ +EEERRLAYVG+TRA ++L Sbjct: 2 DAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRLAYVGITRAEEELV 61 Query: 612 LTYAETRRLYGKEVYHRPSRFIGELPEECVEEV-RLRATVSRPVSHQRMGTPMVENDSGY 670 LT A+ R L+G PSRF+ E+P +E R +A SRP + + V + Sbjct: 62 LTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASRRQAGASRPAVSRPQASGAVG---SW 118 Query: 671 KLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQ-GIKWLVAAYARLESV 720 K+G R H K+G GT+V++ G G+ L +AF GIK L+A +A +E V Sbjct: 119 KVGDRANHRKWGIGTVVSVRGGGDDQELDIAFPSPIGIKRLLAKFAPIEKV 169 >2PJR-B nrPDB Length = 95 Score = 152 bits (384), Expect = 4e-37, Method: Composition-based stats. Identities = 53/93 (56%), Positives = 68/93 (73%) Query: 552 DAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLT 611 DAV LMTLH+AKGLEFP VF++GMEEG+FP SL++ +EEERRLAYVG+TRA ++L Sbjct: 2 DAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRLAYVGITRAEEELV 61 Query: 612 LTYAETRRLYGKEVYHRPSRFIGELPEECVEEV 644 LT A+ R L+G PSRF+ E+P +E Sbjct: 62 LTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETA 94 >1QHH-C nrPDB Length = 115 Score = 110 bits (275), Expect = 2e-24, Method: Composition-based stats. Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Query: 437 LWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQ 496 L++A E L+ L +AA AL F ++ Q + + + V+ SG R M + Sbjct: 1 LFEALGE-LEMIGLGAKAAGALAAFRSQLEQWTQLQEYVSVTELVEEVLDKSGYREMLKA 59 Query: 497 EKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQ 555 E+ + Q+R+ENL+E ++ T+ F +D+ L+ AFL+ AL + + D + A + Sbjct: 60 ERTIEAQSRLENLDEFLSVTKHFENVSDDKSLI---AFLTDLALISDLDELDGTEQAAE 115 >6MBJ-A nrPDB Length = 599 Score = 45.9 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 82/495 (16%), Positives = 158/495 (31%), Gaps = 84/495 (16%) Query: 137 WPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRA 196 W PR+ + + S K+ L P + + + Q + A+ C+RA F + ++ Sbjct: 127 WVPRKLLMTVESAKNSVLGPLY---SQDRILQAMGNIALAFHLLCERASPNSFWQPYIQT 183 Query: 197 ------HELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT--GKVMIVGD 248 L+ + + + + + ++++T QYA+ + + + D Sbjct: 184 LPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTAR-QYAYFYKVIQTHPHANKLPLKD 242 Query: 249 D-DQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKK 307 Y W V ++ N P + R+ ++ + N LI + Sbjct: 243 SFTYEDYRW---AVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDR 299 Query: 308 L----WTDGADGEPISLYCAFNELDEARFVV-----------NRIKTWQDNGGALAECAI 352 D GE I ++ A FV+ +R+K + A+ Sbjct: 300 CECVALQDFRAGEQIYIFYGT--RSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAM 357 Query: 353 LYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVN 412 E L +A +P + F E L++LR+ ++ Sbjct: 358 ----------KAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELK------ 401 Query: 413 TPTRGIGDRTLDVV---------RQTSRDRQLTLWQACRELLQEKALAGRAASALQRFME 463 +GD +D + D ++ LW L RA+ L+ + Sbjct: 402 --EHLLGDSAIDRIFTLGNSEFPVSW--DNEVKLWT---------FLEDRASLLLKTYKT 448 Query: 464 LIDALAQETADMPLHVQTDRVIKDS-GLRTMYEQEKGEKGQTRIENLEELVTATRQFSYN 522 I+ + L V+ IK G + + E+ R +++ Y Sbjct: 449 TIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYE 508 Query: 523 EEDEDLMPLQAFLSHAAL-EAGEGQADTWQDAVQLM-TLHSAKGLEFPQVFIVGMEEGMF 580 E + L+ S L + QDA+ + + AK E G+ Sbjct: 509 ESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAK----------ATENGLV 558 Query: 581 PSQMSLDEGGRLEEE 595 + S+ G R E E Sbjct: 559 NGENSIPNGTRSENE 573 >5LD2-D nrPDB Length = 609 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 52/257 (20%), Positives = 91/257 (35%), Gaps = 42/257 (16%) Query: 388 IKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRE--LL 445 ++D+L L+ D+ ++ RG V +Q D + L Q+ + + Sbjct: 349 LRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAM 408 Query: 446 QEKALAGRAASALQRFMELIDA-------LAQETADMPLHVQTDRVIKDSGLRTMYEQEK 498 E+ALAG R+++L+ A + L + +GL EQ Sbjct: 409 LEEALAGYG-----RYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFM 463 Query: 499 GEKGQT-----------RIENLEELVTATRQFSYN---EEDEDLMPLQAFLSHAALEAGE 544 +K + R + +A F+ + D F Sbjct: 464 QQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSV 523 Query: 545 GQADTWQDAVQ-LMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGV 603 + + MT+H ++G EF ++ PSQ + + R L Y V Sbjct: 524 QPSRLPEHETTWAMTVHKSQGSEFDHAALI------LPSQRT----PVV--TRELVYTAV 571 Query: 604 TRAMQKLTLTYAETRRL 620 TRA ++L+L YA+ R L Sbjct: 572 TRARRRLSL-YADERIL 587 >5CA8-A nrPDB Length = 692 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 32/181 (17%), Positives = 64/181 (35%), Gaps = 32/181 (17%) Query: 34 GKTRVLVH---RIAWLM---SVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQ----- 82 GK+++ H ++ L+ +P +A TFT ++++ L ++ Sbjct: 185 GKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFT----LDLQNMWSSLAKPAELEHLQ 240 Query: 83 -GGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIK-----AMNLDEKQ 136 + TFH L H++L+ + + D+L + L K + +D Sbjct: 241 FADFFDVTFHALNHKVLQPKEFGEGINR------LGDRLVVSNELFKPEYHHDVPIDGWT 294 Query: 137 WPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEA-----CDRAGLVDFAE 191 + I + KD L I ++ + V+Q + + DF E Sbjct: 295 MYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEE 354 Query: 192 L 192 L Sbjct: 355 L 355 >1G71-A nrPDB Length = 347 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 23/148 (15%), Positives = 56/148 (37%), Gaps = 13/148 (8%) Query: 355 RSNAQSRVLE-EALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRN-DDAAFERVVN 412 R N S + + E ++A+ PY +Y + F+E + L+ + + D +R + Sbjct: 49 RKNQYSDIRDLEDYIRATSPYAVYSSVAFYENPREMEGWRGAELVFDIDAKDLPLKRCNH 108 Query: 413 TPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAAS--ALQRFMELIDALAQ 470 P + L+ ++ ++D + L + +GR L + +D+ ++ Sbjct: 109 EPGT-VCPICLEDAKELAKDTLIILREELGFENIHVVYSGRGYHIRILDEWALQLDSKSR 167 Query: 471 E--------TADMPLHVQTDRVIKDSGL 490 E + + +++ G Sbjct: 168 ERILAFISASEIENVEEFRRFLLEKRGW 195 >6FYX-o nrPDB Length = 964 Score = 32.8 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 60/186 (32%), Gaps = 26/186 (13%) Query: 196 AHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYG 255 A + + L+ VD+ Q+T+ Y ++ + D ++ Y Sbjct: 719 AMKKLDHTERALRKVELPLLQKEVDKLQETDTANYEAMKK---------KIVDAAKAEYE 769 Query: 256 WRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADG 315 R A +N+ +D+ ++ +++ T AA I N + Sbjct: 770 ARMADRKNLVMVYDDY-----LKFKEHVSGTKESELAA---IRNQK-------KAELEAA 814 Query: 316 EPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYR 375 + + E + R K N L + + R +EEA + S PY Sbjct: 815 KKARIEEVRKRRYEE--AIARRKEEIANAERQKRAQELAEATRKQREIEEAAAKKSTPYS 872 Query: 376 IYGGMR 381 G R Sbjct: 873 FRAGNR 878 >3SQW-A nrPDB Length = 579 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 62/201 (30%), Gaps = 20/201 (9%) Query: 95 HRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIKAMNLD----EKQWPPRQAMWYINSQK 150 HR+ R + + +D+L ++ L A N+ EK P + + Sbjct: 377 HRIGRT--ARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAV 434 Query: 151 DEGLRPHHIQS---YGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHIL 207 E P I ++ K Y+ + + + + LN P + Sbjct: 435 TE--EPEDISDIVISLISSYRSCIKEYRFSERRILPE--------IASTYGVLLNDPQLK 484 Query: 208 QHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRF 267 RF + L + IR + G DD S +RG + N + Sbjct: 485 IPVSRRFLDKLGLSRSPIGKAMFE-IRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQ 543 Query: 268 LNDFPGAETIRLEQNYRSTSN 288 D+ R N RS S Sbjct: 544 NRDYDDEPFRRSNNNRRSFSR 564 >3DMN-A nrPDB Length = 174 Score = 32.4 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 10/53 (18%) Query: 562 AKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTY 614 AKGLEF V + + E + E+ER+L Y +RAM +LTL Sbjct: 110 AKGLEFDAVIVWNANQ----------ENYQREDERQLLYTICSRAMHELTLVA 152 >6HIX-AE nrPDB Length = 473 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 37/113 (32%), Gaps = 11/113 (9%) Query: 61 TFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQ-ILDSEDQ 119 T+T + + RHR G G + T + L + + D D+ Sbjct: 15 TWTIAVSTQQRHRSGS----GPGDKRIRTDWYRCYPSLMREKDRDMYHCYYPYLFDHGDK 70 Query: 120 LRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQK 172 + L ++ + ++W P Q ++ +++ + +Q Sbjct: 71 MSLYPKI----PENPREWQPEQLQTTYDAIREDKY--DAFIRLREKFPELYQD 117 >2JGD-B nrPDB Length = 933 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 23/160 (14%), Positives = 57/160 (35%), Gaps = 9/160 (5%) Query: 373 PYRIYGGMRFFERQEIKDALSYLRLIANRNDD---AAFERVVNTPT-RGIGDRTLDVVRQ 428 P + + R + R+ KDA Y I++ + + +++N RG LD + Sbjct: 55 PDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGL 114 Query: 429 TSRDRQLTL---WQACRELLQEKALAGRAASALQRFMELIDALAQETADM--PLHVQTDR 483 +D+ L + E ++ + ++ + M+L + L P+ + Sbjct: 115 WQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMH 174 Query: 484 VIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNE 523 + R + ++ + + E + ++ E Sbjct: 175 ITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLE 214 >1K0R-A nrPDB Length = 366 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 44/242 (18%), Positives = 79/242 (32%), Gaps = 51/242 (21%) Query: 475 MPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIE-------------NLEELVTATRQFSY 521 + ++ + + S L T Y +G + RIE +E ++ Sbjct: 36 ISVNELLETI--KSALLTAYRHTQGHQTDARIEIDRKTGVVRVIARETDEAGNLISEW-- 91 Query: 522 NEEDEDLMPLQAFLSHAAL---------EAGEGQADTWQDAVQLMTLH-----SAKGLEF 567 ++ E + A + + E G+ T + + + +A+GL Sbjct: 92 DDTPEGFGRIAATTARQVMLQRFRDAENERTYGEFSTREGEIVAGVIQRDSRANARGL-- 149 Query: 568 PQVFIVGME----EGMFPSQMSLDEGGRLEEERRL--AYVGVTRAMQKLTLTYAET---- 617 V +G E EG+ P+ + G E RL VGVTR ++ +T + T Sbjct: 150 -VVVRIGTETKASEGVIPAAEQVP-GESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNL 207 Query: 618 -RRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRV 676 R+L+ + E+ E R +GQRV Sbjct: 208 VRKLF-SLEVPEIADGSVEIVAVAREAGHRSKIAVRSNVAGLNAKGACIGP----MGQRV 262 Query: 677 RH 678 R+ Sbjct: 263 RN 264 >6AGH-A nrPDB Length = 339 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 29/84 (34%), Gaps = 5/84 (5%) Query: 445 LQEKALAGRAASAL-----QRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKG 499 LQ + R L +RFME + QE + + K+ + Sbjct: 175 LQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLFFTNT 234 Query: 500 EKGQTRIENLEELVTATRQFSYNE 523 E +N+ E ++A S +E Sbjct: 235 ENKDIYWKNVREKLSAGESISLDE 258 >5Z5I-A nrPDB Length = 543 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 23/47 (48%) Query: 311 DGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSN 357 D A GE + +Y A +L + + R W+ GG+ E LY+ N Sbjct: 139 DNARGEELGIYQAEIDLKKGSIIGERKLIWKGTGGSYPEAPHLYKVN 185 >5LJ5-F nrPDB Length = 179 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Query: 418 IGDRTLDVVRQTS---RDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETAD 474 +G L++++ + + +W+ ++L+ E+ +++ EL + L + + D Sbjct: 1 MGSGDLNLLKSWNPKLMKNRKKVWETEQDLITEQQKLNTRLKEIEKERELNELLNESSKD 60 Query: 475 MPLHVQTDRVIKDSGLRTMYEQEK 498 P ++ D +K SGL MY+ K Sbjct: 61 KPETLKNDLALKKSGLEWMYQDAK 84 >2DVL-A nrPDB Length = 372 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 27/83 (32%) Query: 557 MTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAY---------------- 600 M LH+A E V +EE P + L EE R LAY Sbjct: 195 MGLHAAHTAE------VRLEEVFVPEENLLG-----EEGRGLAYALAGLDSGRVGVAAQA 243 Query: 601 VGVTRAMQKLTLTYAETRRLYGK 623 VG+ R ++ YAE R +GK Sbjct: 244 VGIARGAFEIAKAYAEEREQFGK 266 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.130 0.328 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,604,558 Number of Sequences: 36641 Number of extensions: 1006385 Number of successful extensions: 2924 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2827 Number of HSP's gapped (non-prelim): 59 length of query: 720 length of database: 10,336,785 effective HSP length: 104 effective length of query: 616 effective length of database: 6,526,121 effective search space: 4020090536 effective search space used: 4020090536 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 63 (28.9 bits)