BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P02994 (458 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2B7C-A nrPDB 939 0.0 5LZS-jj nrPDB 773 0.0 4C0S-A nrPDB 771 0.0 3WXM-A nrPDB 490 e-139 1JNY-A nrPDB 480 e-136 3WY9-A nrPDB 446 e-125 5LZY-jj nrPDB 344 5e-95 4D61-i nrPDB 313 1e-85 5LZT-jj nrPDB 312 2e-85 1R5O-A nrPDB 305 3e-83 4CRN-P nrPDB 288 4e-78 3MCA-A nrPDB 270 9e-73 3IZQ-1 nrPDB 218 4e-57 3P27-A nrPDB 218 6e-57 4V5G-AZ nrPDB 183 2e-46 1ZUN-B nrPDB 177 7e-45 5W75-A nrPDB 171 4e-43 1MJ1-A nrPDB 170 1e-42 1D2E-A nrPDB 165 5e-41 5W76-A nrPDB 151 7e-37 4ZV4-A nrPDB 146 2e-35 6MIJ-A nrPDB 145 3e-35 4J0Q-A nrPDB 142 4e-34 3MMP-A nrPDB 141 5e-34 1EFM-A nrPDB 136 2e-32 5W7Q-A nrPDB 128 5e-30 2HDN-B nrPDB 122 4e-28 4AC9-A nrPDB 108 5e-24 5HXB-X nrPDB 105 4e-23 4ZU9-A nrPDB 99 4e-21 5IZL-A nrPDB 94 8e-20 5LZD-z nrPDB 79 4e-15 2D74-A nrPDB 77 2e-14 5KCS-1w nrPDB 73 2e-13 4V6V-A1 nrPDB 73 3e-13 5I4Q-C nrPDB 72 5e-13 2YWH-A nrPDB 72 5e-13 5G06-P nrPDB 71 8e-13 4ZKD-A nrPDB 70 2e-12 5A9Z-CA nrPDB 69 6e-12 3CB4-D nrPDB 68 9e-12 5VH6-A nrPDB 67 1e-11 3PEN-A nrPDB 64 2e-10 1S0U-A nrPDB 62 7e-10 6BK7-A nrPDB 59 3e-09 4WQY-BZ nrPDB 57 1e-08 3ZZ0-A nrPDB 57 2e-08 6N0I-A nrPDB 56 3e-08 4FN5-A nrPDB 56 3e-08 4V89-AW nrPDB 56 4e-08 6NOT-A nrPDB 54 1e-07 3WNB-A nrPDB 54 1e-07 6B8D-A nrPDB 54 2e-07 5TY0-A nrPDB 53 2e-07 3TR5-A nrPDB 53 3e-07 3VQT-A nrPDB 52 6e-07 2P8Y-T nrPDB 51 8e-07 5J8B-z nrPDB 51 9e-07 5IMR-C nrPDB 51 1e-06 4KJZ-A nrPDB 51 1e-06 4V7D-BZ nrPDB 51 1e-06 4B44-A nrPDB 51 1e-06 3J4J-A nrPDB 51 1e-06 6FEC-S nrPDB 48 7e-06 6O81-S nrPDB 48 7e-06 5TV2-A nrPDB 48 1e-05 5H7J-A nrPDB 47 2e-05 5H7K-A nrPDB 46 4e-05 4V6W-Az nrPDB 45 5e-05 3J81-k nrPDB 45 6e-05 1WDT-A nrPDB 44 2e-04 3IZY-P nrPDB 41 0.001 6GB2-BC nrPDB 41 0.001 2LKD-A nrPDB 40 0.002 3JCN-b nrPDB 37 0.024 6MTD-v nrPDB 36 0.036 6ID0-C nrPDB 36 0.039 1ZO1-I nrPDB 36 0.045 3JB9-B nrPDB 34 0.14 5KH0-A nrPDB 33 0.19 5YT0-A nrPDB 33 0.35 5FG3-A nrPDB 32 0.51 4H8N-A nrPDB 32 0.59 1UKV-G nrPDB 32 0.75 1G7S-A nrPDB 32 0.75 4KQT-A nrPDB 31 0.99 4LDO-A nrPDB 31 1.3 4NCL-A nrPDB 31 1.4 4V8Y-CP nrPDB 31 1.4 1DOD-A nrPDB 30 1.5 4N3G-A nrPDB 30 1.5 4GBR-A nrPDB 30 1.6 3SN6-R nrPDB 30 1.6 3P0G-A nrPDB 30 1.7 4FID-A nrPDB 30 1.7 4V8Z-CV nrPDB 30 1.8 4NCF-A nrPDB 30 1.8 5U4I-v nrPDB 30 1.8 3WBI-A nrPDB 30 1.9 2R4S-A nrPDB 30 1.9 5J40-A nrPDB 30 3.0 3LG8-A nrPDB 30 3.0 4TN1-B nrPDB 30 3.1 4UJC-AB nrPDB 29 4.4 2CXX-A nrPDB 28 9.0 >2B7C-A nrPDB Length = 458 Score = 939 bits (2427), Expect = 0.0, Method: Compositional matrix adjust. Identities = 458/458 (100%), Positives = 458/458 (100%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL Sbjct: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV Sbjct: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG Sbjct: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT Sbjct: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG Sbjct: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD Sbjct: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG Sbjct: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 Query: 421 RFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK 458 RFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK Sbjct: 421 RFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK 458 >5LZS-jj nrPDB Length = 462 Score = 773 bits (1997), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/460 (80%), Positives = 408/460 (88%), Gaps = 3/460 (0%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 MGKEK+HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAE+GKGSFKYAWVL Sbjct: 1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 DKLKAERERGITIDI+LWKFET KY VT+IDAPGHRDFIKNMITGTSQADCA+LI+A GV Sbjct: 61 DKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV 120 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEIVKETSNFIKK 178 GEFEAGISK+GQTREHALLA+TLGV+QLIV VNKMDS + + + R++EIVKE S +IKK Sbjct: 121 GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKK 180 Query: 179 VGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 +GYNP TV FVPISGWNGDNM+E + N PW+KGW+ K G G TLLEA+D I P+R Sbjct: 181 IGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTR 240 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE 298 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGV+KPGMVVTFAP VTTEVKSVEMHHE L Sbjct: 241 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS 300 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 + +PGDNVGFNVKNVSVK++RRGNV GD+KNDPP A F A VI+LNHPGQISAGY+PV Sbjct: 301 EALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPV 360 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 LDCHTAHIAC+F EL EK DRRSGKKLED PKFLKSGDAA+V VP KPMCVE+FS+YPP Sbjct: 361 LDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPP 420 Query: 419 LGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAK 457 LGRFAVRDMRQTVAVGVIK+VD K A KVTK+AQKA K Sbjct: 421 LGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQK 460 >4C0S-A nrPDB Length = 463 Score = 771 bits (1991), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/460 (79%), Positives = 413/460 (89%), Gaps = 3/460 (0%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 MGKEK+HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAE+GKGSFKYAWVL Sbjct: 1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 DKLKAERERGITIDI+LWKFET KY +T+IDAPGHRDFIKNMITGTSQADCA+LI+A GV Sbjct: 61 DKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV 120 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEIVKETSNFIKK 178 GEFEAGISK+GQTREHALLA+TLGV+QLIV VNKMDS + + E R+ EIVKE S +IKK Sbjct: 121 GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKK 180 Query: 179 VGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 +GYNP TVPFVPISGW+GDNM+E + N PW+KGW+ E K G G +LLEA+D I P+R Sbjct: 181 IGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTR 240 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE 298 PTDKPLRLPLQDVYKIGGIGTVPVGRVETG+++PGMVVTFAP +TTEVKSVEMHHE L Sbjct: 241 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALS 300 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 + +PGDNVGFNVKNVSVK+IRRGNVCGD+K+DPP+ A F + VI+LNHPGQISAGYSPV Sbjct: 301 EALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPV 360 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 +DCHTAHIAC+F EL EK DRRSGKKLED+PK LKSGDAA+V+ VP KPMCVE+FS+YPP Sbjct: 361 IDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPP 420 Query: 419 LGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAK 457 LGRFAVRDMRQTVAVGVIK+V+ K+ A KVTK+AQKA K Sbjct: 421 LGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQK 460 >3WXM-A nrPDB Length = 447 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 239/454 (52%), Positives = 324/454 (71%), Gaps = 19/454 (4%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 EK H+N+VVIGHVD GKST GHL+Y+ G I+++ +++ E++A GK SFK+AW+LDK+ Sbjct: 6 EKPHMNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESFKFAWILDKM 65 Query: 64 KAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEF 123 K ERERGITID+ KFET KY T+IDAPGHRDF+KNMITG SQAD AIL+++ GEF Sbjct: 66 KEERERGITIDLTFMKFETKKYVFTIIDAPGHRDFVKNMITGASQADAAILVVSARKGEF 125 Query: 124 EAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--VKWDESRFQEIVKETSNFIKKVGY 181 EAG+S +GQTREH LLA T+G+ Q+IVAVNKMD+ V +D+ R++ +V F+K +GY Sbjct: 126 EAGMSTEGQTREHLLLARTMGIEQIIVAVNKMDAPDVNYDQKRYEFVVSVLKKFMKGLGY 185 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 +PF+P+S W GDN+IE + N PWY G TL+EA+D ++ P++P D Sbjct: 186 QVDKIPFIPVSAWKGDNLIERSPNMPWY------------NGPTLVEALDQLQPPAKPVD 233 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 KPLR+P+Q+VY I G GTVPVGRVETGV++ G V F P GV EV+S+EMH++QL+Q Sbjct: 234 KPLRIPVQNVYSIPGAGTVPVGRVETGVLRVGDKVVFMPPGVVGEVRSIEMHYQQLQQAE 293 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PGDN+GF V+ VS +I+RG+V G + PP F A + V+ HP I+ GY+PV+ Sbjct: 294 PGDNIGFAVRGVSKSDIKRGDVAGHL-DKPPTVAEEFEARIFVIWHPSAITVGYTPVIHV 352 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HTA ++ R E+ K D ++G+ +E +P+FLK+GDAA+V+F P KP+ VE FSE P LGR Sbjct: 353 HTASVSSRIIEIKAKLDPKTGQVVEQNPQFLKAGDAAIVRFKPVKPLVVEKFSEIPQLGR 412 Query: 422 FAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKA 455 FA+RDM +TV +G++ V K AKV A+ A Sbjct: 413 FAMRDMNRTVGIGIVTDV----KPAKVDIKAKLA 442 >1JNY-A nrPDB Length = 435 Score = 480 bits (1236), Expect = e-136, Method: Compositional matrix adjust. Identities = 234/447 (52%), Positives = 318/447 (71%), Gaps = 19/447 (4%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 +K H+N++VIGHVD GKST G L+ G ID++T+++ E+ A +LGK S K+A++LD+L Sbjct: 3 QKPHLNLIVIGHVDHGKSTLVGRLLMDRGFIDEKTVKEAEEAAKKLGKESEKFAFLLDRL 62 Query: 64 KAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEF 123 K ERERG+TI++ +FET KY T+IDAPGHRDF+KNMITG SQAD AIL+++ GE+ Sbjct: 63 KEERERGVTINLTFMRFETKKYFFTIIDAPGHRDFVKNMITGASQADAAILVVSAKKGEY 122 Query: 124 EAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEIVKETSNFIKKVGY 181 EAG+S +GQTREH +LA T+G+ QLIVAVNKMD + +DE R++EIV + S F++ G+ Sbjct: 123 EAGMSVEGQTREHIILAKTMGLDQLIVAVNKMDLTEPPYDEKRYKEIVDQVSKFMRSYGF 182 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 N V FVP+ +GDN+ + N WY G TL E +D +E P +P D Sbjct: 183 NTNKVRFVPVVAPSGDNITHKSENMKWY------------NGPTLEEYLDQLELPPKPVD 230 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 KPLR+P+QDVY I G+GTVPVGRVE+GV+K G + F PAG EV+S+E HH ++++ Sbjct: 231 KPLRIPIQDVYSISGVGTVPVGRVESGVLKVGDKIVFMPAGKVGEVRSIETHHTKMDKAE 290 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PGDN+GFNV+ V K+I+RG+V G N+PP F A +IV+ HP ++ GY+PVL Sbjct: 291 PGDNIGFNVRGVEKKDIKRGDVVGHP-NNPPTVADEFTARIIVVWHPTALANGYTPVLHV 349 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HTA +ACR EL+ K D R+G++ E +P+FLK GD A+VKF P KP+CVE ++E+PPLGR Sbjct: 350 HTASVACRVSELVSKLDPRTGQEAEKNPQFLKQGDVAIVKFKPIKPLCVEKYNEFPPLGR 409 Query: 422 FAVRDMRQTVAVGVIKSVDKTEKAAKV 448 FA+RDM +TV VG+I V K AKV Sbjct: 410 FAMRDMGKTVGVGIIVDV----KPAKV 432 >3WY9-A nrPDB Length = 434 Score = 446 bits (1147), Expect = e-125, Method: Compositional matrix adjust. Identities = 231/451 (51%), Positives = 305/451 (67%), Gaps = 31/451 (6%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M KEK H+N+V IGHVD GKSTT G L+Y G I + I+KFE E E GK SFK+AWV+ Sbjct: 1 MPKEKPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFE-EMGEKGK-SFKFAWVM 58 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 D+LK ERERGITID+A KFETP +T+IDAPGHRDF+KNMITG SQAD A+L++A Sbjct: 59 DRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAATD 118 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 G QT+EHA LA TLG++ +IV +NKMD V +D+ F+++ + +K +G Sbjct: 119 GVMP-------QTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLKTLG 171 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 Y K P +P S WNGDN+++ + PWY G TL+EA+D I +P +P Sbjct: 172 Y--KDFPVIPTSAWNGDNVVKKSDKMPWYNG------------PTLIEALDQIPEPEKPI 217 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAG------VTTEVKSVEMHH 294 DKPLR+P+QDVY I G+GTVPVGRVETG +K G VV F PA + EVKS+EMHH Sbjct: 218 DKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPASTIFHKPIQGEVKSIEMHH 277 Query: 295 EQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPP--KGCASFNATVIVLNHPGQIS 352 E L++ +PGDN+GFNV+ VS +I+RG+V G P + +F A +IVLNHP I+ Sbjct: 278 EPLQEALPGDNIGFNVRGVSKNDIKRGDVAGHTDKPPTVVRTKDTFKAQIIVLNHPTAIT 337 Query: 353 AGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEA 412 GYSPVL HTA I RF+++L K D R+G +E++P+F+K+GD+A+V P KP+ +E Sbjct: 338 VGYSPVLHAHTAQIPVRFEQILAKVDPRTGNIVEENPQFIKTGDSAIVVLRPMKPVVLEP 397 Query: 413 FSEYPPLGRFAVRDMRQTVAVGVIKSVDKTE 443 E P LGRFA+RDM T+A G++ S+ K E Sbjct: 398 VKEIPQLGRFAIRDMGMTIAAGMVISIQKGE 428 >5LZY-jj nrPDB Length = 710 Score = 344 bits (882), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 178/439 (40%), Positives = 257/439 (58%), Gaps = 18/439 (4%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K +N+VVIGHVD+GKST GH++Y G I+KRT+ K+E+E+ + GK SF YAWVLD+ Sbjct: 284 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 343 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ERERG+T+D+ + KFET +T++DAPGH+DFI NMITG +QAD A+L++ GEFE Sbjct: 344 EERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFE 403 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPK 184 AG GQTREH LL +LGV QL VAVNKMD V W + RFQEI + +F+K+ G+ Sbjct: 404 AGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKES 463 Query: 185 TVPFVPISGWNGDNMIEATTNAP---WYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 V F+P SG +G+N+I + ++ WYKG LLE ID+ + P R D Sbjct: 464 DVGFIPTSGLSGENLITRSQSSELTKWYKGL------------CLLEQIDSFKPPQRSID 511 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 KP RL + DV+K G G G++E G I+ G + P T VK + +H E ++ Sbjct: 512 KPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAA 571 Query: 302 PGDNVGFNVKNVSVKEIRRGNV-CGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 GD+V + + + +I G + CG P K C F A +++ N I+ G+ +L Sbjct: 572 AGDHVSLTLVGMDIIKINVGCIFCG--PKVPIKACTRFRARILIFNIEIPITKGFPVLLH 629 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 T L+ ++ +G+ + PKFL G ALV+ +P+ +E + ++ LG Sbjct: 630 YQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELG 689 Query: 421 RFAVRDMRQTVAVGVIKSV 439 RF +R T+A GV+ + Sbjct: 690 RFMLRYGGSTIAAGVVTEI 708 >4D61-i nrPDB Length = 426 Score = 313 bits (802), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 168/439 (38%), Positives = 255/439 (58%), Gaps = 19/439 (4%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+NVV IGHVD+GKST G ++Y G +DKRT+EK+E+EA E + ++ +W LD + Sbjct: 1 KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQ 60 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER++G T+++ FET K T++DAPGH+ F+ NMI G SQAD A+L+I+ GEFE Sbjct: 61 EERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFE 120 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKVGYN 182 G K GQTREHA+LA T GV+ LIV +NKMD +V W R++E ++ F+KKVG+N Sbjct: 121 TGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFN 180 Query: 183 P-KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 P K + F+P SG G N+ E + PWY G + +D + +R D Sbjct: 181 PKKDIHFMPCSGLTGANLKEQSDFCPWYIGL------------PFIPYLDNLPNFNRSVD 228 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 P+RLP+ D YK +GTV +G++E+G I G + P EV + + + Sbjct: 229 GPIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVA 286 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PG+N+ +K + +EI G + D N G +F+A ++++ H I GY+ VL Sbjct: 287 PGENLKIRLKGIEEEEILPGFILCDPNNLCHSG-RTFDAQIVIIEHKSIICPGYNAVLHI 345 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HT L+ D++SG+K + P+F+K + + + +C+E F ++P +GR Sbjct: 346 HTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGR 405 Query: 422 FAVRDMRQTVAVG-VIKSV 439 F +RD +T+A+G V+K V Sbjct: 406 FTLRDEGKTIAIGKVLKLV 424 >5LZT-jj nrPDB Length = 637 Score = 312 bits (799), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 168/439 (38%), Positives = 255/439 (58%), Gaps = 19/439 (4%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+NVV IGHVD+GKST G ++Y G +DKRT+EK+E+EA E + ++ +W LD + Sbjct: 210 KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQ 269 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER++G T+++ FET K T++DAPGH+ F+ NMI G SQAD A+L+I+ GEFE Sbjct: 270 EERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFE 329 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKVGYN 182 G K GQTREHA+LA T GV+ LIV +NKMD +V W R++E ++ F+KKVG+N Sbjct: 330 TGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFN 389 Query: 183 P-KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 P K + F+P SG G N+ E + PWY G + +D + +R D Sbjct: 390 PKKDIHFMPCSGLTGANLKEQSDFCPWYIGL------------PFIPYLDNLPNFNRSVD 437 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 P+RLP+ D YK +GTV +G++E+G I G + P EV + + + Sbjct: 438 GPIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVA 495 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PG+N+ +K + +EI G + D N G +F+A ++++ H I GY+ VL Sbjct: 496 PGENLKIRLKGIEEEEILPGFILCDPNNLCHSG-RTFDAQIVIIEHKSIICPGYNAVLHI 554 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HT L+ D++SG+K + P+F+K + + + +C+E F ++P +GR Sbjct: 555 HTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGR 614 Query: 422 FAVRDMRQTVAVG-VIKSV 439 F +RD +T+A+G V+K V Sbjct: 615 FTLRDEGKTIAIGKVLKLV 633 >1R5O-A nrPDB Length = 467 Score = 305 bits (781), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 170/444 (38%), Positives = 257/444 (57%), Gaps = 25/444 (5%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+N+V IGHVD+GKST G++++ G +DKRT+EK E+EA E GK S+ +W LD Sbjct: 41 KEHVNIVFIGHVDAGKSTLGGNILFLTGMVDKRTMEKIEREAKEAGKESWYLSWALDSTS 100 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ERE+G T+++ FET + +++DAPGH+ ++ NMI G SQAD +L+I+ GEFE Sbjct: 101 EEREKGKTVEVGRAYFETEHRRFSLLDAPGHKGYVTNMINGASQADIGVLVISARRGEFE 160 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKV-GY 181 AG + GQTREHA+LA T G+ L+V +NKMD SV+W E R++E V + S F+++V GY Sbjct: 161 AGFERGGQTREHAVLARTQGINHLVVVINKMDEPSVQWSEERYKECVDKLSMFLRRVAGY 220 Query: 182 NPKT-VPFVPISGWNGDNMIEATTNA--PWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 N KT V ++P+S + G N+ + ++ PWY +G +LLE +D++ R Sbjct: 221 NSKTDVKYMPVSAYTGQNVKDRVDSSVCPWY------------QGPSLLEYLDSMTHLER 268 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSV-EMHHEQL 297 + P +P+ YK +GT+ G++E G IK V P T EV ++ + E++ Sbjct: 269 KVNAPFIMPIASKYK--DLGTILEGKIEAGSIKKNSNVLVMPINQTLEVTAIYDEADEEI 326 Query: 298 EQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSP 357 + GD V V+ +++ G V KN P F A + +L P ++ GYS Sbjct: 327 SSSICGDQVRLRVRG-DDSDVQTGYVLTSTKN-PVHATTRFIAQIAILELPSILTTGYSC 384 Query: 358 VLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYP 417 V+ HTA F +LL K D ++ +K + P F G + + P+C+E F +Y Sbjct: 385 VMHIHTAVEEVSFAKLLHKLD-KTNRKSKKPPMFATKGMKIIAELETQTPVCMERFEDYQ 443 Query: 418 PLGRFAVRDMRQTVAVG-VIKSVD 440 +GRF +RD TVAVG V+K +D Sbjct: 444 YMGRFTLRDQGTTVAVGKVVKILD 467 >4CRN-P nrPDB Length = 430 Score = 288 bits (736), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 165/438 (37%), Positives = 251/438 (57%), Gaps = 21/438 (4%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H++++ +GHVD+GKST G+L+Y G +DKRTIEK+E+EA + G+ + +WV+D K Sbjct: 3 KDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNK 62 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER G TI++ FET K + T++DAPGH+ ++ MI G SQAD +L+I+ GE+E Sbjct: 63 EERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYE 122 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKVGYN 182 G + GQTREHALLA T GV +++V VNKMD +V W + R+ + V SNF++ +GYN Sbjct: 123 TGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYN 182 Query: 183 PKT-VPFVPISGWNGDNMIEAT--TNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRP 239 KT V F+P+SG++G N+ + PWY G TLLE +D + R Sbjct: 183 IKTDVVFMPVSGYSGANLKDHVDPKECPWY------------TGPTLLEYLDTMNHVDRH 230 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHE-QLE 298 + P LP+ K+ +GT+ G++E+G IK G P E++++ E +++ Sbjct: 231 INAPFMLPI--AAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVD 288 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 + G+ V +K V ++I G V KN P K F A + ++ I+AG+S V Sbjct: 289 MAMCGEQVKLRIKGVEEEDISPGFVLTSPKN-PIKSVTKFVAQIAIVELKSIIAAGFSCV 347 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + HTA +LL K ++ + +K + P F K G + P+CVE + +YP Sbjct: 348 MHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQ 407 Query: 419 LGRFAVRDMRQTVAVGVI 436 LGRF +RD T+A+G I Sbjct: 408 LGRFTLRDQGTTIAIGKI 425 >3MCA-A nrPDB Length = 592 Score = 270 bits (690), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 165/439 (37%), Positives = 244/439 (55%), Gaps = 32/439 (7%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +++VV GHVDSGKST G ++++ G I+ R+++K EAA GKGSF YAW+LD + ER Sbjct: 178 VHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTEEER 237 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 RG+T+D+A FE+ K + DAPGHRDFI MI G S AD A+L++ FE G Sbjct: 238 ARGVTMDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGF 297 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNF-IKKVGYNPKTV 186 ++GQTREHA L LG+ +++V+VNK+D + W E RFQEI S+F IK VG+ V Sbjct: 298 LENGQTREHAYLLRALGISEIVVSVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKTSNV 357 Query: 187 PFVPISGWNGDNMIEATTN--APWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPL 244 FVPIS +G N+I+ ++ WY KG TLL A+D + P +P KPL Sbjct: 358 HFVPISAISGTNLIQKDSSDLYKWY------------KGPTLLSALDQLVPPEKPYRKPL 405 Query: 245 RLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQ-GVPG 303 RL + DVY+ TV GRVE G ++ V+ + VK+V + + V G Sbjct: 406 RLSIDDVYRSPRSVTV-TGRVEAGNVQVNQVLYDVSSQEDAYVKNVIRNSDPSSTWAVAG 464 Query: 304 DNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHT 363 D V + ++ V ++R G++ + +N P + SF A + + G I +G + VL Sbjct: 465 DTVTLQLADIEVNQLRPGDILSNYEN-PVRRVRSFVAEIQTFDIHGPILSGSTLVLHLGR 523 Query: 364 AHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVK--FVPSK-PMCVEAFSEYPPLG 420 + +++ N++RS + + S ALV+ F+ P+C+ E P LG Sbjct: 524 TVTSVSL-KIVTVNNKRS--------RHIASRKRALVRISFLDGLFPLCLA--EECPALG 572 Query: 421 RFAVRDMRQTVAVGVIKSV 439 RF +R TVA G++K + Sbjct: 573 RFILRRSGDTVAAGIVKEL 591 >3IZQ-1 nrPDB Length = 611 Score = 218 bits (555), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 122/370 (32%), Positives = 193/370 (52%), Gaps = 46/370 (12%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 H++ VV+GHVD+GKST G L+Y +++ + K ++E+ +GK SFK+AW++D+ E Sbjct: 167 HLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEE 226 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 RERG+T+ I F T + T++DAPGHRDF+ N I G SQAD AIL + FE+G Sbjct: 227 RERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESG 286 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 DGQT+EH LLA +LG+ LI+A+NKMD+V W + RF+EI + ++ +G+ + Sbjct: 287 FDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNI 346 Query: 187 PFVPISG------------------WNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLE 228 +VPISG +NG N++ NA + E E G+ K L Sbjct: 347 NWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENE---GINKDDPFLF 403 Query: 229 AIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVK 288 ++ I PS+ T L L G++E+G I+PG +T P+ + V Sbjct: 404 SVLEI-IPSKKTSNDLAL--------------VSGKLESGSIQPGESLTIYPSEQSCIVD 448 Query: 289 SVEM--------HHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCG--DAKNDPPKGCASF 338 +++ +HE+ + + GD V ++ ++I+ G++ D + C Sbjct: 449 KIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVL 508 Query: 339 NATVIVLNHP 348 T +N P Sbjct: 509 ELTTFDMNRP 518 >3P27-A nrPDB Length = 483 Score = 218 bits (554), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 122/370 (32%), Positives = 193/370 (52%), Gaps = 46/370 (12%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 H++ VV+GHVD+GKST G L+Y +++ + K ++E+ +GK SFK+AW++D+ E Sbjct: 33 HLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEE 92 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 RERG+T+ I F T + T++DAPGHRDF+ N I G SQAD AIL + FE+G Sbjct: 93 RERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESG 152 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 DGQT+EH LLA +LG+ LI+A+NKMD+V W + RF+EI + ++ +G+ + Sbjct: 153 FDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNI 212 Query: 187 PFVPISG------------------WNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLE 228 +VPISG +NG N++ NA + E E G+ K L Sbjct: 213 NWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENE---GINKDDPFLF 269 Query: 229 AIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVK 288 ++ I PS+ T L L G++E+G I+PG +T P+ + V Sbjct: 270 SVLEI-IPSKKTSNDLAL--------------VSGKLESGSIQPGESLTIYPSEQSCIVD 314 Query: 289 SVEM--------HHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCG--DAKNDPPKGCASF 338 +++ +HE+ + + GD V ++ ++I+ G++ D + C Sbjct: 315 KIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVL 374 Query: 339 NATVIVLNHP 348 T +N P Sbjct: 375 ELTTFDMNRP 384 >4V5G-AZ nrPDB Length = 406 Score = 183 bits (464), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 151/448 (33%), Positives = 210/448 (46%), Gaps = 62/448 (13%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T L Y AAE K +DK Sbjct: 8 RTKPHVNVGTIGHVDHGKTTLTAALTYVA--------------AAENPNVEVKDYGDIDK 53 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 ER RGITI+ A ++ET K + +D PGH D+IKNMITG +Q D AIL+++ G Sbjct: 54 APEERARGITINTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGAILVVSAADGP 113 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK-ETSNFIKKVGY 181 QTREH LLA +GV ++V +NK+D V D+ ++V+ E + + + + Sbjct: 114 MP-------QTREHILLARQVGVPYIVVFMNKVDMV--DDPELLDLVEMEVRDLLNQYEF 164 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPT 240 VP + S +E P + E E V K LL+AID I P R Sbjct: 165 PGDEVPVIRGSALLA---LEQMHRNPKTRRGENEW---VDKIWELLDAIDEYIPTPVRDV 218 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPG---MVVTFAPAGVTTEVKSVEMHHEQL 297 DKP +P++DV+ I G GTV GR+E G +K G +V AP T V VEMH + L Sbjct: 219 DKPFLMPVEDVFTITGRGTVATGRIERGKVKVGDEVEIVGLAPETRRTVVTGVEMHRKTL 278 Query: 298 EQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVL------NHPGQI 351 ++G+ GDNVG ++ VS +E+ RG V + P F A+V VL H G Sbjct: 279 QEGIAGDNVGVLLRGVSREEVERGQVLAKPGSITPH--TKFEASVYVLKKEEGGRHTGFF 336 Query: 352 SAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVE 411 S GY P T + +L + + GD KP+ +E Sbjct: 337 S-GYRPQFYFRTTDVTGVV-------------QLPPGVEMVMPGDNVTFTVELIKPVALE 382 Query: 412 AFSEYPPLGRFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ + Sbjct: 383 EGL------RFAIREGGRTVGAGVVTKI 404 >1ZUN-B nrPDB Length = 434 Score = 177 bits (450), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 124/439 (28%), Positives = 214/439 (48%), Gaps = 31/439 (7%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGK--GSFKYAWVL 60 + K + + G+VD GKST G L++ I + +E +++ + G A ++ Sbjct: 20 ERKEMLRFLTCGNVDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKSGTTGDDVDLALLV 79 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 D L+AERE+GITID+A F T K + + D PGH + +NM TG S D AI+++ Sbjct: 80 DGLQAEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILV---- 135 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 +A QTR H+ +A LG++ ++VA+NKMD +DE F+ I + F + + Sbjct: 136 ---DARYGVQTQTRRHSYIASLLGIKHIVVAINKMDLNGFDERVFESIKADYLKFAEGIA 192 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 + P T+ FVP+S GDN++ + +PWY G++L+E ++ +E S Sbjct: 193 FKPTTMAFVPMSALKGDNVVNKSERSPWY------------AGQSLMEILETVEIASDRN 240 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 LR P+Q V + G + +G++ G + P+G ++ VKS+ +LEQ Sbjct: 241 YTDLRFPVQYVNRPNLNFRGFAGTLASGIVHKGDEIVVLPSGKSSRVKSIVTFEGELEQA 300 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 PG V +++ +I RG++ A N P+ +F+A ++ + + G + Sbjct: 301 GPGQAVTLTMED--EIDISRGDLLVHADN-VPQVSDAFDAMLVWMAEEPML-PGKKYDIK 356 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHP-KFLKSGDAALVKFVPSKPMCVEAFSEYPPL 419 T+++ + + D + LE+ P L+ + VK P+ ++ +S Sbjct: 357 RATSYVPGSIASITHRVDVNT---LEEGPASSLQLNEIGRVKVSLDAPIALDGYSSNRTT 413 Query: 420 GRFAVRD--MRQTVAVGVI 436 G F V D TVA G+I Sbjct: 414 GAFIVIDRLTNGTVAAGMI 432 >5W75-A nrPDB Length = 392 Score = 171 bits (434), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 141/442 (31%), Positives = 208/442 (47%), Gaps = 61/442 (13%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+NV IGHVD GKST T + K + G + +DK Sbjct: 2 KPHVNVGTIGHVDHGKSTLTAAIT---------------KYLSLKGLAQYVPYDQIDKAP 46 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 E+ RGITI+I ++ET K ID PGH D+IKNMITG +Q D AIL++A G Sbjct: 47 EEKARGITINITHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGPMP 106 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK-ETSNFIKKVGYNP 183 QTREH LLA +GV +IV +NK D V D+ E+V+ E + + + Y Sbjct: 107 -------QTREHVLLARQVGVPYMIVFINKTDMV--DDPELIELVEMEVRDLLSQYEYPG 157 Query: 184 KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAID-AIEQPSRPTDK 242 VP + S +EA + P ++ ++ + LL+A+D I P R DK Sbjct: 158 DEVPVIKGSALKA---LEAPDD-PNHEAYKPI--------QELLDAMDNYIPDPQRDVDK 205 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVK-----SVEMHHEQL 297 P +P++DV+ I G GTV GR+E G I+PG V G++ E++ SVEM ++L Sbjct: 206 PFLMPIEDVFSITGRGTVVTGRIERGRIRPGDEVEI--IGLSYEIRKTVVTSVEMFRKEL 263 Query: 298 EQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSP 357 ++G+ GDNVG ++ + E+ RG V + P F A V VL + ++P Sbjct: 264 DEGIAGDNVGCLLRGIDKDEVERGQVLAAPGSIKPH--KRFKAEVYVLKK--EEGGRHTP 319 Query: 358 VLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYP 417 + R D L + + + GD ++ P+ +E Sbjct: 320 FFKGYKPQFYIR------TTDVTGEIVLPEGVEMVMPGDHVEMEIELIYPVAIEKGQ--- 370 Query: 418 PLGRFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ V Sbjct: 371 ---RFAIREGGRTVGAGVVTEV 389 >1MJ1-A nrPDB Length = 405 Score = 170 bits (430), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 122/354 (34%), Positives = 173/354 (48%), Gaps = 48/354 (13%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T L Y AAE K +DK Sbjct: 7 RTKRHVNVGTIGHVDHGKTTLTAALTYVA--------------AAENRNVEVKDYGDIDK 52 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 + ER RGITI+ A ++ET K + +D GH D+IKNMITG +Q D AIL+++ G Sbjct: 53 AREERARGITINTAHVEYETAKRHYSHVDCRGHADYIKNMITGAAQMDGAILVVSAADGR 112 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK-ETSNFIKKVGY 181 QTREH LLA +GVR ++V +NK+D V D+ ++V+ E + + + + Sbjct: 113 MR-------QTREHILLARQVGVRYIVVFMNKVDMV--DDRELLDLVEMEVRDLLNQYEF 163 Query: 182 NPKTV------PFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IE 234 V + + + + + N K WE LL+AID I Sbjct: 164 RGDEVRVIRGSALLALEEMHKNRKTKRGENEWVDKIWE------------LLDAIDEYIR 211 Query: 235 QPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPG---MVVTFAPAGVTTEVKSVE 291 R DK + ++DV+ I G GTV GR+E G +K G +V A T V VE Sbjct: 212 TRVRDVDKRFLMRVEDVFTITGRGTVATGRIERGKVKVGDEVEIVGLARETRKTVVTGVE 271 Query: 292 MHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVL 345 MH + L++G+ GDNVG ++ VS +E+ RG V AK F A+V +L Sbjct: 272 MHRKTLQEGIAGDNVGLLLRGVSREEVERGQVL--AKRGSITRHTKFEASVYIL 323 >1D2E-A nrPDB Length = 397 Score = 165 bits (417), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 132/439 (30%), Positives = 202/439 (46%), Gaps = 64/439 (14%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+NV IGHVD GK+T T + K AE G FK +D Sbjct: 1 KPHVNVGTIGHVDHGKTTLTAAIT---------------KILAEGGGAKFKKYEEIDNAP 45 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER RGITI+ A ++ T D PGH D++KNMITGT+ D IL++A G Sbjct: 46 EERARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMP 105 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK-ETSNFIKKVGYNP 183 QTREH LLA +GV ++V VNK D+V+ +S E+V+ E + + GY Sbjct: 106 -------QTREHLLLARQIGVEHVVVYVNKADAVQ--DSEMVELVELEIRELLTEFGYKG 156 Query: 184 KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTDK 242 + P + S +++ + G+ + LL+A+D I P+R +K Sbjct: 157 EETPIIVGSALCALE--------------QRDPELGLKSVQKLLDAVDTYIPVPTRDLEK 202 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA--PAGVTTEVKSVEMHHEQLEQG 300 P LP++ VY I G GTV G +E G++K G F + T V +EM H+ L++ Sbjct: 203 PFLLPVESVYSIPGRGTVVTGTLERGILKKGDECEFLGHSKNIRTVVTGIEMFHKSLDRA 262 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQ---ISAGYSP 357 GDN+G V+ + +++RRG V + P ++ G+ + + P Sbjct: 263 EAGDNLGALVRGLKREDLRRGLVMAKPGSIQPHQKVEAQVYILTKEEGGRHKPFVSHFMP 322 Query: 358 VLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYP 417 V+ T +ACR +L GK+L G+ + + +PM +E Sbjct: 323 VMFSLTWDMACRI--ILP-----PGKELA------MPGEDLKLTLILRQPMILEKGQ--- 366 Query: 418 PLGRFAVRDMRQTVAVGVI 436 RF +RD +T+ G++ Sbjct: 367 ---RFTLRDGNRTIGTGLV 382 >5W76-A nrPDB Length = 385 Score = 151 bits (381), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 131/441 (29%), Positives = 200/441 (45%), Gaps = 65/441 (14%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+N+ IGHVD GK+T T + K AE G+ FK +DK Sbjct: 2 KPHVNIGTIGHVDHGKTTLTAAIT---------------KVLAEKGQAEFKAYDQIDKAP 46 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 E+ERGITI A ++ET +D PGH D++KNMITG +Q D AIL+++ G Sbjct: 47 EEKERGITISTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMP 106 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPK 184 QTREH LLA +GV ++V +NK+D + DE + + E + + Sbjct: 107 -------QTREHILLARQVGVPYIVVFLNKVD-MVDDEELLELVEMEVRELLSSYDFPGD 158 Query: 185 TVPFV---PISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPT 240 +P + + GD +E + ++K L++A+D+ I +P R Sbjct: 159 DIPIIKGSALKALEGD----------------EEGEEAIMK---LMDAVDSYIPEPERAI 199 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLE 298 DKP +P++DV+ I GTV GRVE G++K G V T T VEM + L+ Sbjct: 200 DKPFLMPIEDVFSISR-GTVVTGRVERGIVKVGEEVEIVGIRDTQKTTCTGVEMFRKLLD 258 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 +G GDNVG ++ +++ RG V AK K F A V +L + ++P Sbjct: 259 EGQAGDNVGVLLRGTKREDVERGQVL--AKPGSIKPHTKFKAEVYILTK--EEGGRHTPF 314 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + + R D L + + + GD + P+ +E Sbjct: 315 FNGYRPQFYFR------TTDVTGVITLPEGVEMVMPGDNVTITVELIAPIAMEEGL---- 364 Query: 419 LGRFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ + Sbjct: 365 --RFAIREGGRTVGAGVVSEI 383 >4ZV4-A nrPDB Length = 405 Score = 146 bits (369), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 125/445 (28%), Positives = 200/445 (44%), Gaps = 57/445 (12%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T L C ++ GS + +D Sbjct: 8 RNKPHVNVGTIGHVDHGKTTLTAALTKVC---------------SDTWGGSARAFDQIDN 52 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 E+ RGITI+ + ++++ +D PGH D++KNMITG +Q D AIL+ + G Sbjct: 53 APEEKARGITINTSHVEYDSAVRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGP 112 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK-ETSNFIKKVGY 181 QTREH LL+ +GV ++V +NK D V D++ E+V+ E + + + Sbjct: 113 MP-------QTREHILLSRQVGVPYIVVFLNKADMV--DDAELLELVEMEVRDLLNTYDF 163 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPT 240 P + +A + + GV + L+E +D+ I +P R Sbjct: 164 PGDDTPII-------------IGSALMALEGKDDNGIGVSAVQKLVETLDSYIPEPVRAI 210 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKS--VEMHHEQLE 298 D+P +P++DV+ I G GTV GRVE G+IK V TT+ VEM + L+ Sbjct: 211 DQPFLMPIEDVFSISGRGTVVTGRVERGIIKVQEEVEIVGIKATTKTTCTGVEMFRKLLD 270 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 +G G+NVG ++ +++ RG V AK K F V VL+ + ++P Sbjct: 271 EGRAGENVGILLRGTKREDVERGQVL--AKPGTIKPHTKFECEVYVLSK--EEGGRHTPF 326 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + R D +L + + + GD + P+ +E Sbjct: 327 FKGYRPQFYFR------TTDVTGNCELPEGVEMVMPGDNIKMVVTLIAPIAMEDGL---- 376 Query: 419 LGRFAVRDMRQTVAVGVIKSVDKTE 443 RFA+R+ +TV GV+ + + E Sbjct: 377 --RFAIREGGRTVGAGVVAKIIELE 399 >6MIJ-A nrPDB Length = 396 Score = 145 bits (367), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 130/442 (29%), Positives = 202/442 (45%), Gaps = 60/442 (13%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T + C A+ G K +D Sbjct: 8 RNKPHVNVGTIGHVDHGKTTLTAAIATIC---------------AKTYGGEAKDYSQIDS 52 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 E+ RGITI+ + ++++P +D PGH D++KNMITG +Q D AIL+ A G Sbjct: 53 APEEKARGITINTSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGP 112 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNK--MDSVKWDESRFQEIVKETSNFIKKVG 180 QTREH LL+ +GV +IV +NK + + + V+E + G Sbjct: 113 MP-------QTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELLSTYDFPG 165 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRP 239 + + ++ NG+ P+ E+ A L+ A+D+ I +P R Sbjct: 166 DDTPVIRGSALAALNGE-------AGPY---GEESVLA-------LVAALDSYIPEPERA 208 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA--PAGVTTEVKSVEMHHEQL 297 DK +P++DV+ I G GTV GRVE G+IK G V V T V VEM + L Sbjct: 209 IDKAFLMPIEDVFSISGRGTVVTGRVEAGIIKVGEEVEIVGIKDTVKTTVTGVEMFRKLL 268 Query: 298 EQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSP 357 ++G G+N G ++ +E++RG V AK K F+A V VL+ + ++P Sbjct: 269 DEGRAGENCGILLRGTKREEVQRGQVL--AKPGTIKPHTKFDAEVYVLSK--EEGGRHTP 324 Query: 358 VLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYP 417 L+ + R D +L++ + + GD + P+ ++ Sbjct: 325 FLNGYRPQFYFR------TTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMD------ 372 Query: 418 PLGRFAVRDMRQTVAVGVIKSV 439 P RFA+R+ +TV GV+ V Sbjct: 373 PGLRFAIREGGRTVGAGVVAKV 394 >4J0Q-A nrPDB Length = 433 Score = 142 bits (357), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 126/449 (28%), Positives = 199/449 (44%), Gaps = 64/449 (14%) Query: 1 MGKEK-----SHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFK 55 M KEK H+NV IGHVD GK+T T L C + I +F+K Sbjct: 37 MAKEKFDRSLPHVNVGTIGHVDHGKTTLTAALTRVCSEVFGSAIVEFDK----------- 85 Query: 56 YAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILI 115 +D E+ RGITI+ A ++ + +D PGH D++KNMITG +Q D AIL+ Sbjct: 86 ----IDSAPEEKARGITINTAHVEYNSTIRHYAHVDCPGHADYVKNMITGAAQMDGAILV 141 Query: 116 IAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK-ETSN 174 + G QTREH LL+ +GV ++V +NK D V D++ E+V+ E + Sbjct: 142 CSAADGPMP-------QTREHILLSRQVGVPYIVVFLNKADLV--DDAELLELVEMEVRD 192 Query: 175 FIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-I 233 + + P + +A + + + G K L+E +D+ I Sbjct: 193 LLSTYDFPGDDTPII-------------IGSARMALEGKDDNEMGTTAVKKLVETLDSYI 239 Query: 234 EQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIK---PGMVVTFAPAGVTTEVKSV 290 +P R D+P +P++DV+ I G GTV GR+E G+++ P +V TT V Sbjct: 240 PEPVRAIDQPFLMPIEDVFSISGRGTVVTGRIERGIVRVQDPLEIVGLRDT-TTTTCTGV 298 Query: 291 EMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQ 350 EM + L++G G+N G ++ ++ RG V K K F A V VL+ + Sbjct: 299 EMFRKLLDEGRAGENCGVLLRGTKRDDVERGQVL--VKPGSVKPHTKFTAEVYVLSK--E 354 Query: 351 ISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCV 410 ++P + R D +L + + + GD + K + + Sbjct: 355 EGGRHTPFFKGYRPQFYFR------TTDVTGNCELPEGVEMVMPGDNIQMTVTLIKTIAM 408 Query: 411 EAFSEYPPLGRFAVRDMRQTVAVGVIKSV 439 E RFA+R+ +TV GV+ + Sbjct: 409 EDGL------RFAIREGGRTVGAGVVAKI 431 >3MMP-A nrPDB Length = 678 Score = 141 bits (356), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 114/351 (32%), Positives = 168/351 (47%), Gaps = 52/351 (14%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHL---IYKCGGIDKRTIEKFEKEAAELGKGSFKYAWV 59 + K H+NV IGHVD GK+T T + + K G R ++ Sbjct: 292 RTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQ------------------ 333 Query: 60 LDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGG 119 +D E+ RGITI+ + +++TP +D PGH D++KNMITG +Q D AIL++A Sbjct: 334 IDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAAT 393 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKV 179 G QTREH LL +GV +IV +NK D + DE + + E + + Sbjct: 394 DGPMP-------QTREHILLGRQVGVPYIIVFLNKCD-MVDDEELLELVEMEVRELLSQY 445 Query: 180 GYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRP 239 + P V G + +A W +A +++ L++ I +P R Sbjct: 446 DFPGDDTPIV-----RGSALKALEGDAEW--------EAKILELAGFLDSY--IPEPERA 490 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKS----VEMHHE 295 DKP LP++DV+ I G GTV GRVE G+IK G V G+ KS VEM + Sbjct: 491 IDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEI--VGIKETQKSTCTGVEMFRK 548 Query: 296 QLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLN 346 L++G G+NVG ++ + +EI RG V AK K F + V +L+ Sbjct: 549 LLDEGRAGENVGVLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILS 597 >1EFM-A nrPDB Length = 379 Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 128/441 (29%), Positives = 192/441 (43%), Gaps = 74/441 (16%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T + VL K Sbjct: 7 RTKPHVNVGTIGHVDHGKTTLTAAI-----------------------------TTVLAK 37 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 RGITI+ + +++TP +D PGH D++KNMITG +Q D AIL++A G Sbjct: 38 TYGGAARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGP 97 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LL +GV +IV +NK D + DE + + E + + + Sbjct: 98 MP-------QTREHILLGRQVGVPYIIVFLNKCD-MVDDEELLELVEMEVRELLSQYDFP 149 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDK 242 P V G + +A W +A +++ L++ I +P R DK Sbjct: 150 GDDTPIV-----RGSALKALEGDAEW--------EAKILELAGFLDSY--IPEPERAIDK 194 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKS----VEMHHEQLE 298 P LP++DV+ I G GTV GRVE G+IK G V G+ KS VEM + L+ Sbjct: 195 PFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEI--VGIKETQKSTCTGVEMFRKLLD 252 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 +G G+NVG ++ + +EI RG V AK K F + V +L+ ++P Sbjct: 253 EGRAGENVGVLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILSK--DEGGRHTPF 308 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + R D +L + + + GD + P+ ++ Sbjct: 309 FKGYRPQFYFR------TTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL---- 358 Query: 419 LGRFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ V Sbjct: 359 --RFAIREGGRTVGAGVVAKV 377 >5W7Q-A nrPDB Length = 373 Score = 128 bits (322), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 122/443 (27%), Positives = 192/443 (43%), Gaps = 77/443 (17%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHL---IYKCGGIDKRTIEKFEKEAAELGKGSFKYAWV 59 + K H+N+ IGHVD GK+T T + + K GG + + ++ Sbjct: 1 RTKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGGAEAKAYDQ------------------ 42 Query: 60 LDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGG 119 +D E+ RGITI+ A ++ET +D PGH D++KNMITG +Q D AIL+++ Sbjct: 43 IDNAPEEKARGITINTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAA 102 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKV 179 G QTREH LLA +GV ++V +NK D + DE + + E + + Sbjct: 103 DGPMP-------QTREHILLARQVGVPYIVVFLNKCD-MVDDEELLELVEMEVRELLSEY 154 Query: 180 GYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSR 238 + +P + G + +A W K L++A+D+ I P R Sbjct: 155 DFPGDDIPII-----RGSALKALEGDAEWED-----------KILELMDAVDSYIPTPER 198 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQ 296 DKP +P++DV+ I G GTV GRVE G++K G V T T V VEM Sbjct: 199 DIDKPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIKDTQKTTVTGVEM---- 254 Query: 297 LEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYS 356 VG ++ +++ RG V + P F A V VL+ + ++ Sbjct: 255 ---------VGALLRGTKREDVERGQVLAKPGSITPH--TKFEAEVYVLSK--EEGGRHT 301 Query: 357 PVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEY 416 P + + R D +L + + + GD + P+ +E Sbjct: 302 PFFNGYRPQFYFR------TTDVTGVIELPEGVEMVMPGDNVKMTVELIAPIAMEEGL-- 353 Query: 417 PPLGRFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ + Sbjct: 354 ----RFAIREGGRTVGAGVVSKI 372 >2HDN-B nrPDB Length = 335 Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 111/374 (29%), Positives = 171/374 (45%), Gaps = 45/374 (12%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GITI+ + +++TP +D PGH D++KNMITG +Q D AIL++A G Sbjct: 1 GITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMP----- 55 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QTREH LL +GV +IV +NK D + DE + + E + + + P V Sbjct: 56 --QTREHILLGRQVGVPYIIVFLNKCD-MVDDEELLELVEMEVRELLSQYDFPGDDTPIV 112 Query: 190 PISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQ 249 G + +A W +A +++ L++ I +P R DKP LP++ Sbjct: 113 -----RGSALKALEGDAEW--------EAKILELAGFLDSY--IPEPERAIDKPFLLPIE 157 Query: 250 DVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKS----VEMHHEQLEQGVPGDN 305 DV+ I G GTV GRVE G+IK G V G+ KS VEM + L++G G+N Sbjct: 158 DVFSISGRGTVVTGRVERGIIKVGEEVEI--VGIKETQKSTCTGVEMFRKLLDEGRAGEN 215 Query: 306 VGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAH 365 VG ++ + +EI RG V AK K F + V +L+ ++P + Sbjct: 216 VGVLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILSK--DEGGRHTPFFKGYRPQ 271 Query: 366 IACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVR 425 R D +L + + + GD + P+ ++ RFA+R Sbjct: 272 FYFR------TTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL------RFAIR 319 Query: 426 DMRQTVAVGVIKSV 439 + +TV GV+ V Sbjct: 320 EGGRTVGAGVVAKV 333 >4AC9-A nrPDB Length = 482 Score = 108 bits (270), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 83/318 (26%), Positives = 141/318 (44%), Gaps = 56/318 (17%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 +IN+ + GH+D GK+T K E+ S DKL Sbjct: 19 NINLGIFGHIDHGKTT-------------------LSKVLTEIASTSAH-----DKLPES 54 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 ++RGITIDI F+ Y++T++DAPGH D I+ +++ D A++++ G Sbjct: 55 QKRGITIDIGFSAFKLENYRITLVDAPGHADLIRAVVSAADIIDLALIVVDAKEGP---- 110 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 QT EH L+ + +IV + K D+ +E + E++ ++ I + +N K Sbjct: 111 ---KTQTGEHMLILDHFNI-PIIVVITKSDNAGTEEIKRTEMIMKS---ILQSTHNLKNS 163 Query: 187 PFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRL 246 +PIS G GV + K L+ + R T+ ++ Sbjct: 164 SIIPISAKTG---------------------FGVDELKNLIITTLNNAEIIRNTESYFKM 202 Query: 247 PLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNV 306 PL + I G GTV G + G++K G + P ++T+V+S++ E + + GD V Sbjct: 203 PLDHAFPIKGAGTVVTGTINKGIVKVGDELKVLPINMSTKVRSIQYFKESVMEAKAGDRV 262 Query: 307 GFNVKNVSVKEIRRGNVC 324 G ++ V K+I RG + Sbjct: 263 GMAIQGVDAKQIYRGCIL 280 >5HXB-X nrPDB Length = 199 Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 58/192 (30%), Positives = 101/192 (52%), Gaps = 3/192 (1%) Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVP 302 P+RLP+ D YK +GTV +G++E+G I G + P EV + + + P Sbjct: 4 PIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVAP 61 Query: 303 GDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCH 362 G+N+ +K + +EI G + D N G +F+A ++++ H I GY+ VL H Sbjct: 62 GENLKIRLKGIEEEEILPGFILCDPNNLCHSG-RTFDAQIVIIEHKSIICPGYNAVLHIH 120 Query: 363 TAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRF 422 T L+ D++SG+K + P+F+K + + + +C+E F ++P +GRF Sbjct: 121 TCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRF 180 Query: 423 AVRDMRQTVAVG 434 +RD +T+A+G Sbjct: 181 TLRDEGKTIAIG 192 >4ZU9-A nrPDB Length = 582 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 87/310 (28%), Positives = 135/310 (43%), Gaps = 64/310 (20%) Query: 14 GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITI 73 GHVD GK+T LI GID D+L E++RG++I Sbjct: 10 GHVDHGKTT----LIKTLTGIDT------------------------DRLPEEKKRGLSI 41 Query: 74 DIALWKFETPKY--QVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDG 131 DI + P ++ +ID PGH FIKN I G A IL++ G Sbjct: 42 DIGFAYIDFPDINTRLEIIDVPGHERFIKNAIAGICSASGLILVVDPNEGIMP------- 94 Query: 132 QTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPI 191 QT EH +A + G++ I + KMD V + + E +E F++K N + V + Sbjct: 95 QTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAE--EELIAFLEKEEMNMEIVKVSAV 152 Query: 192 SGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDV 251 +G IE N+ K LLE+I+ + + KPLR+ + Sbjct: 153 TGQG----IEDLKNSI----------------KKLLESINNLNK-----HKPLRIFVDSA 187 Query: 252 YKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVK 311 + + G GTV G G +K G V P GV + V+ ++ H +++ V G+ + N+ Sbjct: 188 FVVKGYGTVLRGSCFEGEVKEGDKVVVEPIGVISRVRKMQNHGVFVKKAVAGERIALNLP 247 Query: 312 NVSVKEIRRG 321 V K+++RG Sbjct: 248 EVDAKKVKRG 257 >5IZL-A nrPDB Length = 616 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 90/353 (25%), Positives = 140/353 (39%), Gaps = 76/353 (21%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M + ++NV V+GH+DSGK+ R + AA Sbjct: 21 MAGRRVNVNVGVLGHIDSGKTALA------------RALSTTASTAA------------F 56 Query: 61 DKLKAERERGITIDIALWKFETPK-------------------------YQVTVIDAPGH 95 DK RERGIT+D+ F P QVT++D PGH Sbjct: 57 DKQPQSRERGITLDLGFSCFSVPLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGH 116 Query: 96 RDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAF-TLGVRQLIVAVNK 154 I+ +I G D +L+I ++K QT+ L + ++L+V +NK Sbjct: 117 ASLIRTIIGGAQIIDLMMLVI---------DVTKGMQTQSAECLVIGQIACQKLVVVLNK 167 Query: 155 MDSVKWDESRFQEIVKETSNFIKKVGYNPKT--VPFVPISGWNGDNMIEATTNAPWYKGW 212 +D + E + Q + + + ++K N K P +P++ G AP Sbjct: 168 IDLLP--EGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGG------PEAP----- 214 Query: 213 EKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKP 272 E E G+ + LL + I P+R P + + + I G GTV G + +G I Sbjct: 215 ETEAPQGIPELIELLTS--QISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISL 272 Query: 273 GMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCG 325 G V V +VKS++M H + + GD +G V K + RG VC Sbjct: 273 GDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCA 325 >5LZD-z nrPDB Length = 614 Score = 79.0 bits (193), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 91/401 (22%), Positives = 158/401 (39%), Gaps = 78/401 (19%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 + GHVD GK+T L+ G++ D+L E++R Sbjct: 3 IATAGHVDHGKTT----LLQAITGVNA------------------------DRLPEEKKR 34 Query: 70 GITIDIALWKFETPKYQVT-VIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 G+TID+ + P +V ID PGH F+ NM+ G D A+L++A G Sbjct: 35 GMTIDLGYAYWPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVM----- 89 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 QTREH + G L VA+ K D V DE+R E+ ++ +++ G+ + Sbjct: 90 --AQTREHLAILQLTGNPMLTVALTKADRV--DEARVDEVERQVKEVLREYGFAEAKL-- 143 Query: 189 VPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPL 248 I A T +G + L E + + + + RL + Sbjct: 144 ----------FITAATEG---RGMD-----------ALREHLLQLPEREHASQHSFRLAI 179 Query: 249 QDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGF 308 + + G G V G +G +K G + V+++ ++ E G + Sbjct: 180 DRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIAL 239 Query: 309 NVKNVSVKE-IRRGN-VCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTA-H 365 N+ + KE I RG+ + D +P F ++ L ++ + P+ H A H Sbjct: 240 NIAGDAEKEQINRGDWLLADVPPEP------FTRVIVELQTHTPLTQ-WQPLHIHHAASH 292 Query: 366 IACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSK 406 + R LLE N + + D P +L D +++ + ++ Sbjct: 293 VTGRV-SLLEDN---LAELVFDTPLWLADNDRLVLRDISAR 329 >2D74-A nrPDB Length = 419 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 95/377 (25%), Positives = 152/377 (40%), Gaps = 113/377 (29%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 ++ +N+ ++GHVD GK+T T + W D Sbjct: 9 QAEVNIGMVGHVDHGKTTLTK---------------------------ALTGVWT-DTHS 40 Query: 65 AERERGITIDIALWKFETPK-----------------------YQVTVIDAPGHRDFIKN 101 E RGITI I E + +V+ ID+PGH + Sbjct: 41 EELRRGITIKIGFADAEIRRCSNCGRYSTSPICPYCGHETEFIRRVSFIDSPGHEALMTT 100 Query: 102 MITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWD 161 M+ G S D AIL+IA QTREH + +G + +I+A NK++ V D Sbjct: 101 MLAGASLMDGAILVIAANEP------CPRPQTREHLMALQIIGQKNIIIAQNKIELV--D 152 Query: 162 ESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVV 221 + + E ++ FIK G + P +PIS +G N+ Sbjct: 153 KEKALENYRQIKEFIK--GTVAENAPIIPISALHGANI---------------------- 188 Query: 222 KGKTLLEAIDA-IEQPSRPTDKP---LRLPLQDVYK--------IGGI--GTVPVGRVET 267 L++AI+ I P R ++KP L L DV K +GG+ G++ G+++ Sbjct: 189 --DVLVKAIEEFIPTPKRDSNKPPKMLVLRSFDVNKPGTPPEKLVGGVLDGSIVQGKLKV 246 Query: 268 G---VIKPGMV------VTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVK---NVSV 315 G I+PG+ + + P +TTE+ S++ + +E+ PG VG K ++ Sbjct: 247 GDEIEIRPGVPYEEHGRIKYEP--ITTEIVSLQAGGQFVEEAYPGGLVGIGTKLDPYLTK 304 Query: 316 KEIRRGNVCGDAKNDPP 332 ++ GNV G PP Sbjct: 305 GDLMAGNVVGKPGKLPP 321 >5KCS-1w nrPDB Length = 639 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 52/164 (31%), Positives = 77/164 (46%), Gaps = 21/164 (12%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 IN+ V+ HVD+GK+T T L+Y G I E + KG+ + D ER Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAI---------TELGSVDKGTTR----TDNTLLER 50 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +RGITI + F+ +V +ID PGH DF+ + S D AIL+I+ + G+ Sbjct: 51 QRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISA-----KDGV 105 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 + HAL + I +NK+D D S + +KE Sbjct: 106 QAQTRILFHALRKMGIPT---IFFINKIDQNGIDLSTVYQDIKE 146 >4V6V-A1 nrPDB Length = 639 Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 57/185 (30%), Positives = 93/185 (50%), Gaps = 35/185 (18%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELG---KGSFKYAWVLDKLK 64 IN+ ++ HVD+GK+T T L+Y G I AELG +G+ + D + Sbjct: 4 INLGILAHVDAGKTTLTESLLYTSGAI------------AELGSVDEGTTR----TDTMN 47 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER+RGITI A+ F+ +V +ID PGH DF+ + S D A+L+++ Sbjct: 48 LERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVS------- 100 Query: 125 AGISKDGQTREHALLAFTLGVRQL--IVAVNKMDSVKWDESR-FQEIVKETSNFI---KK 178 +KDG + +L L + ++ I +NK+D D ++E+ + S+ I +K Sbjct: 101 ---AKDGIQAQTRILFHALQIMKIPTIFFINKIDQEGIDLPMVYREMKAKLSSEIIVKQK 157 Query: 179 VGYNP 183 VG +P Sbjct: 158 VGQHP 162 >5I4Q-C nrPDB Length = 217 Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 63/211 (29%), Positives = 95/211 (45%), Gaps = 22/211 (10%) Query: 233 IEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKS--- 289 I +P R DKP LP++DV+ I G GTV GRVE G+IK G V G+ KS Sbjct: 23 IPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEI--VGIKETQKSTCT 80 Query: 290 -VEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHP 348 VEM + L++G G+NVG ++ + +EI RG V AK K F + V +L+ Sbjct: 81 GVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILSK- 137 Query: 349 GQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPM 408 ++P + R D +L + + + GD + P+ Sbjct: 138 -DEGGRHTPFFKGYRPQFYFR------TTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPI 190 Query: 409 CVEAFSEYPPLGRFAVRDMRQTVAVGVIKSV 439 ++ RFA+R+ +TV GV+ V Sbjct: 191 AMDDGL------RFAIREGGRTVGAGVVAKV 215 >2YWH-A nrPDB Length = 600 Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 84/335 (25%), Positives = 138/335 (41%), Gaps = 63/335 (18%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 ++K+ N +I HVD GKST L+ G I +R EK E+ +LD Sbjct: 2 EQKNVRNFCIIAHVDHGKSTLADRLLEYTGAISER--EKREQ--------------LLDT 45 Query: 63 LKAERERGITIDI-ALWKFETPK----YQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 L ERERGIT+ + A+ F K Y++ +ID PGH DF + + + A+L+I Sbjct: 46 LDVERERGITVKMQAVRMFYKAKDGNTYKLHLIDTPGHVDFSYEVSRALAACEGALLLID 105 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIK 177 G ++ + E L+ +I +NK+D D R ++ ++E Sbjct: 106 ASQGIEAQTVANFWKAVEQDLV--------IIPVINKIDLPSADVDRVKKQIEE------ 151 Query: 178 KVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPS 237 + G + + I A+ K G+ + L ++ I P Sbjct: 152 -------------VLGLDPEEAILAS------------AKEGIGIEEILEAIVNRIPPPK 186 Query: 238 RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQL 297 KPL+ + D Y G V R+ G +KPG + G EV V ++ Sbjct: 187 GDPQKPLKALIFDSYYDPYRGAVAFVRIFDGEVKPGDKIMLMSTGKEYEVTEVGAQTPKM 246 Query: 298 EQ--GVPGDNVGFNVKNV-SVKEIRRGNVCGDAKN 329 + + +VG+ ++ V++IR G+ AKN Sbjct: 247 TKFDKLSAGDVGYIAASIKDVRDIRIGDTITHAKN 281 >5G06-P nrPDB Length = 747 Score = 71.2 bits (173), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 15/208 (7%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELG-KGSFKYAWVLDKLKA 65 ++ + +G ++GKST GHL+Y I ++ + +K+++ L S + +LD K Sbjct: 267 NLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKVILDNTKT 326 Query: 66 ERERGITIDIALWKFET----PKYQVTVIDAPGH-RDFIKNMITG--TSQADCAILIIAG 118 ERE G ++ + + E P +T+ID PG + F K + T + +L+I Sbjct: 327 ERENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSILTFDPEVYVLVIDC 386 Query: 119 GVGEFEAGIS-KDGQTREHALLAFTLG-----VRQLIVAVNKMDSVKWDESRFQEIVKET 172 +E + + Q E + L + LI+ +NK D + WD+ R + I E Sbjct: 387 NYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKADLISWDKHRLEMIQSEL 446 Query: 173 SNFIKK-VGYNPKTVPFVPISGWNGDNM 199 + +K+ + F+P SG G N+ Sbjct: 447 NYVLKENFQWTDAEFQFIPCSGLLGSNL 474 >4ZKD-A nrPDB Length = 499 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 15/208 (7%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELG-KGSFKYAWVLDKLKA 65 ++ + +G ++GKST GHL+Y I ++ + +K+++ L S + +LD K Sbjct: 19 NLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKVILDNTKT 78 Query: 66 ERERGITIDIALWKFET----PKYQVTVIDAPGH-RDFIKNMITG--TSQADCAILIIAG 118 ERE G ++ + + E P +T+ID PG + F K + T + +L+I Sbjct: 79 ERENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSILTFDPEVYVLVIDC 138 Query: 119 GVGEFEAGIS-KDGQTREHALLAFTLG-----VRQLIVAVNKMDSVKWDESRFQEIVKET 172 +E + + Q E + L + LI+ +NK D + WD+ R + I E Sbjct: 139 NYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKADLISWDKHRLEMIQSEL 198 Query: 173 SNFIKK-VGYNPKTVPFVPISGWNGDNM 199 + +K+ + F+P SG G N+ Sbjct: 199 NYVLKENFQWTDAEFQFIPCSGLLGSNL 226 >5A9Z-CA nrPDB Length = 593 Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 117/281 (41%), Gaps = 59/281 (20%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ +I HVD GK+T L+ + G D R E E+ V+D E+E Sbjct: 7 NIAIIAHVDHGKTTLVDKLLQQSGTFDSRA-ETQER--------------VMDSNDLEKE 51 Query: 69 RGITI---DIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEA 125 RGITI + A K++ Y++ ++D PGH DF + S D +L++ G Sbjct: 52 RGITILAKNTAAIKWD---YRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMP- 107 Query: 126 GISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKT 185 QTR AF G++ ++V +NK+D +R +V + + + + Sbjct: 108 ------QTRFVTKKAFAYGLKPIVV-INKVDRPG---ARPDWVVDQVFDLFVNLDATDEQ 157 Query: 186 VPFV--------PISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPS 237 + F I+G + ++M E T P Y+ +D + P Sbjct: 158 LDFAIVYASALNGIAGLDHEDMAEDMT--PLYQAI-----------------VDHVPAPD 198 Query: 238 RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTF 278 D P ++ + + +G + +GR++ G +KP VT Sbjct: 199 VDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTI 239 >3CB4-D nrPDB Length = 599 Score = 67.8 bits (164), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 51/170 (30%), Positives = 77/170 (45%), Gaps = 33/170 (19%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N +I H+D GKST + +I CGG+ R +E A VLD + ERE Sbjct: 6 NFSIIAHIDHGKSTLSDRIIQICGGLSDREME----------------AQVLDSMDLERE 49 Query: 69 RGITI-------DIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 RGITI D ET YQ+ ID PGH DF + + + A+L++ G G Sbjct: 50 RGITIKAQSVTLDYKASDGET--YQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQG 107 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 + QT + A + + +++ +NK+D D R E +++ Sbjct: 108 -------VEAQTLANCYTAMEMDL-EVVPVLNKIDLPAADPERVAEEIED 149 >5VH6-A nrPDB Length = 409 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 49/153 (32%), Positives = 77/153 (50%), Gaps = 21/153 (13%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ ++ H+D+GK+TTT +++ G I K E +G+ + W ++ E+E Sbjct: 15 NIGIMAHIDAGKTTTTERILFYTGRIHK---------IGETHEGASQMDW----MEQEQE 61 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 RGITI A + Y+V +ID PGH DF T + + ++ ++ G V +A Sbjct: 62 RGITITSAATTAQWKGYRVNIIDTPGHVDF-------TVEVERSLRVLDGAVAVLDAQSG 114 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWD 161 + QT A T GV + IV VNKMD + D Sbjct: 115 VEPQTETVWRQATTYGVPR-IVFVNKMDKIGAD 146 >3PEN-A nrPDB Length = 403 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 96/209 (45%), Gaps = 38/209 (18%) Query: 3 KEKSHINVVVIGHVDSGKST----TTGHLIYKCGGIDKRTI---EKFEKEAAELGKGSFK 55 K + +N+ V+GHVD GK+T TG K G + I E +K A + + S K Sbjct: 4 KVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKKLGYAETNIGVCESCKKPEAYVTEPSCK 63 Query: 56 YAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILI 115 D+ K R +++ IDAPGH + M++G + D AIL+ Sbjct: 64 SCGSDDEPKFLR------------------RISFIDAPGHEVLMATMLSGAALMDGAILV 105 Query: 116 IAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNF 175 +A F QTREH + +GV+ LI+ NK+D V +E+ Q ++ F Sbjct: 106 VAAN-EPF-----PQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQ--YRQIKQF 157 Query: 176 IKKVGYNPKTVPFVPISGW---NGDNMIE 201 K G + VP +P+S N D++IE Sbjct: 158 TK--GTWAENVPIIPVSALHKINIDSLIE 184 >1S0U-A nrPDB Length = 408 Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 53/203 (26%), Positives = 97/203 (47%), Gaps = 31/203 (15%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKG-SFKYAWVLDKL 63 ++ +N+ ++GHVD GK++ T L T ++ + EL +G S + + ++ Sbjct: 6 QAEVNIGMVGHVDHGKTSLTKAL----------TGVWTDRHSEELRRGISIRLGYADCEI 55 Query: 64 KAERERGITID-------IALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 + + G +A +F +V+ +D+PGH + M++G S D AIL+I Sbjct: 56 RKCPQCGTYTTKPRCPNCLAETEF---LRRVSFVDSPGHETLMATMLSGASLMDGAILVI 112 Query: 117 AGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFI 176 A QT+EH + LG+ ++I+ NK+D V DE + +E ++ F+ Sbjct: 113 AANEP------CPQPQTKEHLMALEILGIDKIIIVQNKIDLV--DEKQAEENYEQIKEFV 164 Query: 177 KKVGYNPKTVPFVPISGWNGDNM 199 K G + P +PIS + N+ Sbjct: 165 K--GTIAENAPIIPISAHHEANI 185 >6BK7-A nrPDB Length = 407 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 21/153 (13%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ ++ HVD+GK+TTT ++Y G I K E +G+ + W ++ E+E Sbjct: 15 NIGIMAHVDAGKTTTTERILYYTGKIHK---------IGETHEGASQMDW----MEQEQE 61 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 RGITI A + Y+V +ID PGH DF T + ++ ++ G V ++ Sbjct: 62 RGITITSAATTAQWKGYRVNIIDTPGHVDF-------TIEVQRSLRVLDGAVTVLDSQSG 114 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWD 161 + QT A V + IV NKMD + D Sbjct: 115 VEPQTETVWRQATEYKVPR-IVFCNKMDKIGAD 146 >4WQY-BZ nrPDB Length = 758 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 13/113 (11%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + H+D+GK+TTT ++Y G I K E+ +G A +D ++ ERE Sbjct: 81 NIGIAAHIDAGKTTTTERILYYTGRIHK---------IGEVHEG----AATMDFMEQERE 127 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 RGITI A+ +++ +ID PGH DF + D AI++ G Sbjct: 128 RGITITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQG 180 >3ZZ0-A nrPDB Length = 693 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 48/150 (32%), Positives = 75/150 (50%), Gaps = 21/150 (14%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ +I H+D+GK+TTT ++Y G I K E +G+ + W ++ E++ Sbjct: 12 NIGIIAHIDAGKTTTTERILYYTGRIHK---------IGETHEGASQMDW----MEQEQD 58 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 RGITI A ++V +ID PGH DF T + + ++ ++ G V +A Sbjct: 59 RGITITSAATTAAWEGHRVNIIDTPGHVDF-------TVEVERSLRVLDGAVTVLDAQSG 111 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSV 158 + QT A T GV + IV VNKMD + Sbjct: 112 VEPQTETVWRQATTYGVPR-IVFVNKMDKL 140 >6N0I-A nrPDB Length = 706 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 49/185 (26%), Positives = 81/185 (43%), Gaps = 39/185 (21%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ ++ HVD+GK+TTT +++ G + E+ G+ W + E+E Sbjct: 15 NIGIVAHVDAGKTTTTERILFYTG---------VNHKMGEVHDGAATMDW----MAQEQE 61 Query: 69 RGITID----IALWKFETP----KYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAG-- 118 RGITI A W+ T KY+ +ID PGH DF + D A+++ +G Sbjct: 62 RGITITSAATTAFWQGSTKQFAHKYRFNIIDTPGHVDFTIEVERSLRVLDGAVVVFSGAD 121 Query: 119 GVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKK 178 GV + + LA+ +NKMD D F +VK+ ++ Sbjct: 122 GVEPQSETVWRQANKYHVPRLAY----------INKMDRQGAD---FLRVVKQID---QR 165 Query: 179 VGYNP 183 +G++P Sbjct: 166 LGHHP 170 >4FN5-A nrPDB Length = 709 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 82/182 (45%), Gaps = 34/182 (18%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + HVD+GK+TTT +++ G + E+ G+ W++ E+E Sbjct: 15 NIGICAHVDAGKTTTTERVLFYTG---------VNHKLGEVHDGAATTDWMVQ----EQE 61 Query: 69 RGITIDIA----LWKF---ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 RGITI A WK + Y+V VID PGH DF + D A+++ G Sbjct: 62 RGITITSAAVTTFWKGSRGQYDNYRVNVIDTPGHVDFTIEVERSLRVLDGAVVVFCG--- 118 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGY 181 +G+ +T A GV + IV VNKMD + R E +K K++G+ Sbjct: 119 --TSGVEPQSETVWRQ--ANKYGVPR-IVYVNKMDRQGANFLRVVEQIK------KRLGH 167 Query: 182 NP 183 P Sbjct: 168 TP 169 >4V89-AW nrPDB Length = 534 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 48/178 (26%), Positives = 84/178 (47%), Gaps = 25/178 (14%) Query: 12 VIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGI 71 +I H D+GK+T T ++ I K G+GS ++A D ++ E++RGI Sbjct: 18 IISHPDAGKTTITEKVLLFGQAIQTAGTVK--------GRGSNQHAKS-DWMEMEKQRGI 68 Query: 72 TIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII--AGGVGEFEAGISK 129 +I ++ +F V ++D PGH DF ++ + DC +++I A GV + + + Sbjct: 69 SITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLME 128 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 + R+ +L F +NK+D D E++ E N + K+G P T P Sbjct: 129 VTRLRDTPILTF----------MNKLDRDIRDP---MELLDEVENEL-KIGCAPITWP 172 >6NOT-A nrPDB Length = 707 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 25/165 (15%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + H+D+GK+TTT ++Y G K E+ +G W ++ E+E Sbjct: 20 NIGICAHIDAGKTTTTERILYYTGKSHK---------IGEVHEGGATMDW----MEQEQE 66 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE--AG 126 RGITI A + +ID PGH DF T + + ++ ++ G V F+ AG Sbjct: 67 RGITITSAATTCRWQDKVINIIDTPGHVDF-------TIEVERSLRVLDGAVAVFDGVAG 119 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 + +T + + + VNKMD + D R E++K+ Sbjct: 120 VEPQSETVWRQADKYNV---PRMCFVNKMDRMGADFYRCVEMIKD 161 >3WNB-A nrPDB Length = 370 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 30/261 (11%) Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 ++G + DI ++ + + +DA + +K++IT + +D A+L I G+ Sbjct: 43 KKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITALNISDIAVLCIP------PQGL 96 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 D T E + LG + I+A+ + DS + E +K + TV Sbjct: 97 --DAHTGECIIALDLLGFKHGIIALTRSDSTHM------HAIDELKAKLKVI--TSGTV- 145 Query: 188 FVPISGWNGDNMIEATTNAPWYKGWE--KETKAGVVKGKTLLEAIDAIEQPSRPTDKPLR 245 + W I TN +E E KA + + E I+A + + P R Sbjct: 146 ---LQDWE---CISLNTNKSAKNPFEGVDELKARI---NEVAEKIEA--ENAELNSLPAR 194 Query: 246 LPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDN 305 + + + + G G V +G V+ G+ K P E++S++ H ++ G Sbjct: 195 IFIDHAFNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTR 254 Query: 306 VGFNVKNVSVKEIRRGNVCGD 326 VG +KNV K+I RG + D Sbjct: 255 VGMRLKNVQAKDIERGFIISD 275 >6B8D-A nrPDB Length = 408 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 32/171 (18%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + H+D+GK+TTT +++ G + E+ G+ W ++ E+E Sbjct: 15 NIGISAHIDAGKTTTTERILFYTG---------VSHKIGEVHDGAATMDW----MEQEQE 61 Query: 69 RGITID----IALWK---FETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA--GG 119 RGITI A W + P++++ VID PGH DF + D A+++ GG Sbjct: 62 RGITITSAATTAFWSGMSQQFPQHRINVIDTPGHVDFTVEVERSMRVLDGAVMVYCAVGG 121 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK 170 V + + E +AF VNKMD + R E +K Sbjct: 122 VQPQSETVWRQANKYEVPRIAF----------VNKMDRTGANFLRVVEQLK 162 >5TY0-A nrPDB Length = 422 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 49/163 (30%), Positives = 80/163 (49%), Gaps = 32/163 (19%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K + N+ + HVD+GK+TTT ++Y G + E+ G+ W++ Sbjct: 9 KLYRNIGIAAHVDAGKTTTTERVLYYTG---------MSHKIGEVHDGAATMDWMVQ--- 56 Query: 65 AERERGITIDIA----LW-----KFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILI 115 E+ERGITI A W +FE+ +++ +ID PGH DF MI + + ++ + Sbjct: 57 -EQERGITITSAATTCYWSGMDKQFES--HRINIIDTPGHVDF---MI----EVERSLRV 106 Query: 116 IAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSV 158 + G V F++ + Q+ A GV + IV VNKMD + Sbjct: 107 LDGAVVVFDSVAGVEPQSETVWRQANKYGVPR-IVFVNKMDRM 148 >3TR5-A nrPDB Length = 528 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 9/110 (8%) Query: 12 VIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGI 71 +I H D+GK+T T L+ G I K K A D ++ E++RGI Sbjct: 18 IISHPDAGKTTLTEKLLLFGGAIQLAGTIKSRKAARHATS---------DWMELEKQRGI 68 Query: 72 TIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 ++ ++ +F Y + ++D PGH DF ++ + D A+++I G Sbjct: 69 SVTTSVMQFPYKDYLINLLDTPGHADFTEDTYRTLTAVDSALMVIDAAKG 118 >3VQT-A nrPDB Length = 548 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 17/145 (11%) Query: 12 VIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGI 71 +I H D+GK+T T L+ G I K K A D + ERERGI Sbjct: 36 IISHPDAGKTTLTEKLLLFGGAIQMAGSVKARKAARHATS---------DWMAMERERGI 86 Query: 72 TIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDG 131 ++ ++ +F V ++D PGH+DF ++ + D A+++I +A + Sbjct: 87 SVTTSVMQFPYRDRVVNLLDTPGHQDFSEDTYRVLTAVDSALVVI-------DAAKGVEA 139 Query: 132 QTREHALLAFTLGVRQLIVAVNKMD 156 QTR+ + + ++ VNKMD Sbjct: 140 QTRK-LMDVCRMRATPVMTFVNKMD 163 >2P8Y-T nrPDB Length = 842 Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 31/132 (23%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M K + N+ VI HVD GKST T L+ + G I AA+ G+ F Sbjct: 13 MDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGII----------SAAKAGEARFT----- 57 Query: 61 DKLKAERERGITID---IALW-------------KFETPKYQVTVIDAPGHRDFIKNMIT 104 D K E+ERGITI I+L+ K + + + +ID+PGH DF + Sbjct: 58 DTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTA 117 Query: 105 GTSQADCAILII 116 D A++++ Sbjct: 118 ALRVTDGALVVV 129 >5J8B-z nrPDB Length = 679 Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 93/232 (40%), Gaps = 38/232 (16%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTI-EKFEKEAAELGKGSFKYAWVLDKLKAER 67 N +I HVD GKST ++ + R + E+F LD L+ ER Sbjct: 80 NFSIIAHVDHGKSTLADRILELTHAVSDREMREQF-----------------LDSLELER 122 Query: 68 ERGITIDIALWKF-----ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 ERGITI + + + +Y +ID PGH DF + + + +L++ G Sbjct: 123 ERGITIKASAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGV 182 Query: 123 FEAGISKDGQTREHALLAFTL-------GVRQLIVA--VNKMDSVKWDESRFQ-----EI 168 ++K EH + + R L VA V ++ + DE+ F E Sbjct: 183 EAETLAKFYMALEHGHVIIPVINKIDLPNARPLEVALEVEEVLGLPADEAIFASGKTGEG 242 Query: 169 VKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNA-PWYKGWEKETKAG 219 V+E I + PK P P+ D++ +A P+ + +E + G Sbjct: 243 VEEILEAIVQRIPPPKGDPEAPLKALIFDSVYDAYQGVIPYLRLFEGRVRPG 294 >5IMR-C nrPDB Length = 610 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 93/232 (40%), Gaps = 38/232 (16%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTI-EKFEKEAAELGKGSFKYAWVLDKLKAER 67 N +I HVD GKST ++ + R + E+F LD L+ ER Sbjct: 11 NFSIIAHVDHGKSTLADRILELTHAVSDREMREQF-----------------LDSLELER 53 Query: 68 ERGITIDIALWKF-----ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 ERGITI + + + +Y +ID PGH DF + + + +L++ G Sbjct: 54 ERGITIKASAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGV 113 Query: 123 FEAGISKDGQTREHALLAFTL-------GVRQLIVA--VNKMDSVKWDESRFQ-----EI 168 ++K EH + + R L VA V ++ + DE+ F E Sbjct: 114 EAETLAKFYMALEHGHVIIPVINKIDLPNARPLEVALEVEEVLGLPADEAIFASGKTGEG 173 Query: 169 VKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNA-PWYKGWEKETKAG 219 V+E I + PK P P+ D++ +A P+ + +E + G Sbjct: 174 VEEILEAIVQRIPPPKGDPEAPLKALIFDSVYDAYQGVIPYLRLFEGRVRPG 225 >4KJZ-A nrPDB Length = 473 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 39/192 (20%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV++GHVD GK+T +L R EKEA Sbjct: 75 VVIMGHVDHGKTTLLDYL---------RKSRIAEKEAG---------------------- 103 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT + ++ +TP+ V ID PGH F G AD A+++IA G Sbjct: 104 GITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGIMP----- 158 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QT E A G + LI A+NK+D + D + + + E ++ G + +P Sbjct: 159 --QTEEAIAHAKAAGAK-LIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPIS 215 Query: 190 PISGWNGDNMIE 201 +G +++E Sbjct: 216 AKTGQGVQDLLE 227 >4V7D-BZ nrPDB Length = 711 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 38/184 (20%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + H+D+GK+TTT +++ G + E+ G+ W ++ E+E Sbjct: 11 NIGISAHIDAGKTTTTERILFYTG---------VNHKIGEVHDGAATMDW----MEQEQE 57 Query: 69 RGITI----DIALWKFETPKYQ---VTVIDAPGHRDFIKNMITGTSQADCAILII--AGG 119 RGITI A W +Y+ + +ID PGH DF + D A+++ GG Sbjct: 58 RGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGG 117 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKV 179 V + + + +AF VNKMD + + F ++V + ++ Sbjct: 118 VQPQSETVWRQANKYKVPRIAF----------VNKMDRMG---ANFLKVVNQIKT---RL 161 Query: 180 GYNP 183 G NP Sbjct: 162 GANP 165 >4B44-A nrPDB Length = 363 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 39/192 (20%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV++GHVD GK+T +L R EKEA Sbjct: 76 VVIMGHVDHGKTTLLDYL---------RKSRIAEKEAG---------------------- 104 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT + ++ +TP+ V ID PGH F G AD A+++IA G Sbjct: 105 GITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGIMP----- 159 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QT E A G + LI A+NK+D + D + + + E ++ G + +P Sbjct: 160 --QTEEAIAHAKAAGAK-LIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPIS 216 Query: 190 PISGWNGDNMIE 201 +G +++E Sbjct: 217 AKTGQGVQDLLE 228 >3J4J-A nrPDB Length = 569 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 45/195 (23%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV++GHVD GK+T +L R EKEA Sbjct: 76 VVIMGHVDHGKTTLLDYL---------RKSRIAEKEAG---------------------- 104 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT + ++ +TP+ V ID PGH F G AD A+++IA + Sbjct: 105 GITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIA----------AD 154 Query: 130 DG---QTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 DG QT E A G + LI A+NK+D + D + + + E ++ G + + Sbjct: 155 DGIMPQTEEAIAHAKAAGAK-LIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVI 213 Query: 187 PFVPISGWNGDNMIE 201 P +G +++E Sbjct: 214 PISAKTGQGVQDLLE 228 >6FEC-S nrPDB Length = 422 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 10/108 (9%) Query: 86 QVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGV 145 V+ +D PGH + M+ G + D A+L+IAG QT EH + + Sbjct: 91 HVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKL 144 Query: 146 RQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISG 193 + +++ NK+D VK ES+ +E ++ F++ G + P +PIS Sbjct: 145 KHILILQNKIDLVK--ESQAKEQYEQILAFVQ--GTVAEGAPIIPISA 188 >6O81-S nrPDB Length = 472 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 10/107 (9%) Query: 86 QVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGV 145 V+ +D PGH + M+ G + D A+L+IAG QT EH + + Sbjct: 129 HVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKL 182 Query: 146 RQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPIS 192 + +++ NK+D VK ES+ +E ++ F++ G + P +PIS Sbjct: 183 KHILILQNKIDLVK--ESQAKEQYEQILAFVQ--GTVAEGAPIIPIS 225 >5TV2-A nrPDB Length = 405 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 39/191 (20%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + HVD+GK+TTT +++ G + E+ G+ W ++ E+E Sbjct: 12 NIGICAHVDAGKTTTTERILFYTG---------LSHKIGEVHDGAATMDW----MEQEQE 58 Query: 69 RG----ITIDIALWKFETPKYQ---VTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 RG W+ ++Q V +ID PGH DF + D A+++ G Sbjct: 59 RGITITSAATTTFWRGMEAQFQDHRVNIIDTPGHVDFTIEVERSLRVLDGAVVVFCGS-- 116 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGY 181 +G+ +T + + +V VNKMD D F +V + N ++G Sbjct: 117 ---SGVEPQSETVWRQADKYHV---PRMVFVNKMDRAGAD---FLRVVDQIKN---RLGA 164 Query: 182 NPKTVPFVPIS 192 NP VPI Sbjct: 165 NP-----VPIQ 170 >5H7J-A nrPDB Length = 743 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 44/188 (23%), Positives = 80/188 (42%), Gaps = 37/188 (19%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + H+D GK+T + +L+ G I + K VLD + E+ Sbjct: 26 NIGIAAHIDHGKTTLSDNLLAGAGMISEELAGK---------------QLVLDFDEQEQA 70 Query: 69 RGITIDIA----LWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 RGITI+ A + +E Y + +ID PGH DF ++ D I++ V E Sbjct: 71 RGITINAANVSMVHNYEGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIV----VDAVE 126 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSV--------KWDESRFQEIVKETSNFI 176 + + AL + + ++ +NK+D + + RF +I+ + + I Sbjct: 127 GVMPQTETVVRQALREYV----KPVLFINKVDRLIRELKLTPQQMMERFSKIIMDVNRLI 182 Query: 177 KKVGYNPK 184 ++ Y P+ Sbjct: 183 QR--YAPE 188 >5H7K-A nrPDB Length = 397 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 44/188 (23%), Positives = 80/188 (42%), Gaps = 37/188 (19%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+ + H+D GK+T + +L+ G I + K VLD + E+ Sbjct: 26 NIGIAAHIDHGKTTLSDNLLAGAGMISEELAGK---------------QLVLDFDEQEQA 70 Query: 69 RGITIDIA----LWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 RGITI+ A + +E Y + +ID PGH DF ++ D I++ V E Sbjct: 71 RGITINAANVSMVHNYEGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIV----VDAVE 126 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSV--------KWDESRFQEIVKETSNFI 176 + + AL + + ++ +NK+D + + RF +I+ + + I Sbjct: 127 GVMPQTETVVRQALREYV----KPVLFINKVDRLIRELKLTPQQMMERFSKIIMDVNRLI 182 Query: 177 KKVGYNPK 184 ++ Y P+ Sbjct: 183 QR--YAPE 188 >4V6W-Az nrPDB Length = 844 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 40/137 (29%), Positives = 61/137 (44%), Gaps = 37/137 (27%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M K+++ N+ VI HVD GKST T L+ K G I A+ G+ F Sbjct: 13 MDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGII----------AGAKAGETRFT----- 57 Query: 61 DKLKAERERGITID---IALWKFETPK------------------YQVTVIDAPGHRDFI 99 D K E+ER ITI I+++ FE + + + +ID+PGH DF Sbjct: 58 DTRKDEQERCITIKSTAISMY-FEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFS 116 Query: 100 KNMITGTSQADCAILII 116 + D A++++ Sbjct: 117 SEVTAALRVTDGALVVV 133 >3J81-k nrPDB Length = 527 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 35/206 (16%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAA-ELGKGSFKYAWVLDK 62 ++ IN+ IGHV GKST ++ G+ R ++ E+ +LG + K + Sbjct: 98 QATINIGTIGHVAHGKST----VVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEP 153 Query: 63 LKAERE--RGITIDIALWKFETPKYQ-------------VTVIDAPGHRDFIKNMITGTS 107 E + R D K +PK Q V+ +D PGH + M++G + Sbjct: 154 TCPEPDCYRSFKSD----KEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAA 209 Query: 108 QADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQE 167 D A+L+IAG QT EH + ++ +I+ NK+D ++ E E Sbjct: 210 VMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR--EESALE 261 Query: 168 IVKETSNFIKKVGYNPKTVPFVPISG 193 K FI+ G P VPIS Sbjct: 262 HQKSILKFIR--GTIADGAPIVPISA 285 >1WDT-A nrPDB Length = 665 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 23/158 (14%) Query: 1 MGKEKSHI--NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAW 58 MG E + V ++GH SGK+T T L+YK G ++R E G + Y Sbjct: 1 MGTEGGAMIRTVALVGHAGSGKTTLTEALLYKTGAKERRG-------RVEEGTTTTDYT- 52 Query: 59 VLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAG 118 + K R T+ + ++V ++DAPG+ DF+ + AD A++ ++ Sbjct: 53 --PEAKLHR---TTVRTGVAPLLFRGHRVFLLDAPGYGDFVGEIRGALEAADAALVAVSA 107 Query: 119 GVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMD 156 EAG+ T +A LG+ +++V V K+D Sbjct: 108 -----EAGVQVG--TERAWTVAERLGLPRMVV-VTKLD 137 >3IZY-P nrPDB Length = 537 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 40/195 (20%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++GHVD GK+T +DK + K + A E G Sbjct: 7 VTIMGHVDHGKTTL----------LDK--LRKTQVAAMEAG------------------- 35 Query: 70 GITIDIALWKFETPK-YQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 GIT I + P ++T +D PGH F GT D IL++A G + + Sbjct: 36 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGTQVTDIVILVVAADDGVMKQTV- 94 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 ++ +HA A +++A+NK D + D + ++ + + G + + V Sbjct: 95 ---ESIQHAKDAHV----PIVLAINKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVHV 147 Query: 189 VPISGWNGDNMIEAT 203 ++G N + EAT Sbjct: 148 SALTGENMMALAEAT 162 >6GB2-BC nrPDB Length = 657 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 43/192 (22%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++GHVD GK+T ++KF K ++ A Sbjct: 113 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 141 Query: 70 GITIDIALWKFETPK-YQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 GIT I + P ++T +D PGH F G D +L++A G + + Sbjct: 142 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 200 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 ++ +HA A +I+AVNK D + D + ++ + + G + V Sbjct: 201 ---ESIQHAKDAQV----PIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGD---VQA 250 Query: 189 VPISGWNGDNMI 200 VP+S GDN++ Sbjct: 251 VPVSALTGDNLM 262 >2LKD-A nrPDB Length = 178 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 58/150 (38%), Gaps = 23/150 (15%) Query: 50 GKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQA 109 GK + A K+ + GIT I ++ ++T +D PGH F G Sbjct: 20 GKTTLLDAIRHSKVTEQEAGGITQHIGAYQVTVNDKKITFLDTPGHEAFTTMRARGAQVT 79 Query: 110 DCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIV 169 D IL++A G + + HA A +IVA+NKMD + + R + + Sbjct: 80 DIVILVVAADDGVMPQTV----EAINHAKAANV----PIIVAINKMDKPEANPDRVMQEL 131 Query: 170 KETSNFIKKVGYNPKTVPFVPISGWNGDNM 199 E YN VP W GD + Sbjct: 132 ME---------YN-----LVP-EEWGGDTI 146 >3JCN-b nrPDB Length = 890 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 23/52 (44%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 GIT I + ET +T +D PGH F G D +L++A G Sbjct: 423 GITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDG 474 >6MTD-v nrPDB Length = 839 Score = 35.8 bits (81), Expect = 0.036, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 21/118 (17%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA--ELGKGSFKYAW 58 M K+ + N+ VI HVD GKST T L+ K G I + K + EL + + Sbjct: 12 MDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIARCITIKSTAISLFYELSENDLNF-- 69 Query: 59 VLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 +K ++ + + +ID+PGH DF + D A++++ Sbjct: 70 ----IKQSKDGA-------------GFLINLIDSPGHVDFSSEVTAALRVTDGALVVV 110 >6ID0-C nrPDB Length = 972 Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 19/118 (16%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 NV + GH+ GK+ LI E+ E+ K + D L E+E Sbjct: 131 NVTLCGHLHHGKTCFVDCLI--------------EQTHPEIRKRYDQDLCYTDILFTEQE 176 Query: 69 RGITI-----DIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 RG+ I + L + Y ++D PGH +F + G +D +L I G Sbjct: 177 RGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEG 234 >1ZO1-I nrPDB Length = 501 Score = 35.8 bits (81), Expect = 0.045, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 22/48 (45%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 GIT I + ET +T +D PGH F G D +L++A Sbjct: 36 GITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVA 83 >3JB9-B nrPDB Length = 984 Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust. Identities = 26/113 (23%), Positives = 46/113 (40%), Gaps = 19/113 (16%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 + +V GH+ GKS L+Y + + S +Y D ERE Sbjct: 143 SFIVAGHLHHGKSALLDLLVYYT-----------HPDTKPPKRRSLRYT---DTHYLERE 188 Query: 69 RGITI-----DIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 R ++I +A+ + + ID PGH DF+ + + +D +L++ Sbjct: 189 RVMSIKSTPLTLAVSDMKGKTFAFQCIDTPGHVDFVDEVAAPMAISDGVVLVV 241 >5KH0-A nrPDB Length = 396 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 19/119 (15%) Query: 49 LGKGSFKYAWVLDKLK-AERERGITIDIALWKFE-TPKYQVTVIDAPGHRDF-------I 99 +GK SF A + ++ G T D E +P +T+ID PG D I Sbjct: 19 VGKSSFMNALIGQEVSIVSNVAGTTTDPVFKSMELSPVGPITLIDTPGLDDVGELGIKRI 78 Query: 100 KNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSV 158 K +ADC ILI+ G FE I K +E + F +A+NK+D++ Sbjct: 79 KKAKKSLYRADCGILIVDDIPGNFEEQIIK--LFKELEIPYF--------IAINKIDTI 127 >5YT0-A nrPDB Length = 364 Score = 32.7 bits (73), Expect = 0.35, Method: Compositional matrix adjust. Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 21/111 (18%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAAELGK---GSFKYAWVLDKLKA 65 VVV+GHVD GK+T +DK R KEA + + S A V++K+ Sbjct: 19 VVVLGHVDHGKTTL----------LDKIRRTAVAAKEAGGITQHIGASIVPADVIEKIAE 68 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 ++ I + + + ID PGH F G S AD AIL++ Sbjct: 69 PLKKVIPVKLVIPGL-------LFIDTPGHELFSNLRRRGGSVADFAILVV 112 >5FG3-A nrPDB Length = 623 Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust. Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 21/111 (18%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAAELGK---GSFKYAWVLDKLKA 65 VVV+GHVD GK+T +DK R KEA + + S A V++K+ Sbjct: 19 VVVLGHVDHGKTTL----------LDKIRRTAVAAKEAGGITQHIGASIVPADVIEKIAE 68 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 ++ I + + + ID PGH F G S AD AIL++ Sbjct: 69 PLKKVIPVKLVIPGL-------LFIDTPGHELFSNLRRRGGSVADFAILVV 112 >4H8N-A nrPDB Length = 310 Score = 32.0 bits (71), Expect = 0.59, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 384 KLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTV 431 ++E HP FL++ +V+F + VEAFS PL R + +T+ Sbjct: 189 QIEFHP-FLQNQSKNIVRFCQEHGILVEAFSPLAPLARVETNALAETL 235 >1UKV-G nrPDB Length = 453 Score = 31.6 bits (70), Expect = 0.75, Method: Compositional matrix adjust. Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 10/100 (10%) Query: 191 ISGWNGDNMIEATTNAPWYK-GWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQ 249 +S G ++ + T + +YK G TK + L D ++QP+RP+ + + L Q Sbjct: 165 LSTHQGLDLDKNTMDEVYYKFGLGNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQ 224 Query: 250 DV---------YKIGGIGTVPVGRVETGVIKPGMVVTFAP 280 V Y + G+G +P G I G + P Sbjct: 225 SVARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDTP 264 >1G7S-A nrPDB Length = 594 Score = 31.6 bits (70), Expect = 0.75, Method: Compositional matrix adjust. Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 25/151 (16%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V V+GHVD GK+T H+ R +EA + + +D ++ Sbjct: 8 VSVLGHVDHGKTTLLDHI---------RGSAVASREAGGITQHIGATEIPMDVIE----- 53 Query: 70 GITIDIALWKFETPKYQ--VTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 GI D L KF + + ID PGH F G + AD AILI+ + G Sbjct: 54 GICGDF-LKKFSIRETLPGLFFIDTPGHEAFTTLRKRGGALADLAILIV-----DINEGF 107 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSV 158 QT+E AL + +VA NK+D + Sbjct: 108 KP--QTQE-ALNILRMYRTPFVVAANKIDRI 135 >4KQT-A nrPDB Length = 195 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 3/84 (3%) Query: 222 KGKTLLEAIDAIEQPSRP-TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAP 280 KG+ + ++A EQ + + L P+Q VY+ +V + R + P M +T A Sbjct: 104 KGQLRQKEVEATEQKALSRVYQELNTPIQQVYQAQKC-SVLLDREAVMLANPAMDITDAV 162 Query: 281 -AGVTTEVKSVEMHHEQLEQGVPG 303 A + +K++ E+L+Q VPG Sbjct: 163 VAALDARIKTLTFDRERLDQQVPG 186 >4LDO-A nrPDB Length = 469 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 343 IVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKK 384 I+LN G +++G++P++ C + F ELL RRS K Sbjct: 430 ILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCL--RRSSLK 469 >4NCL-A nrPDB Length = 457 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 31/124 (25%) Query: 6 SHIN--------VVVIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAA----ELGKG 52 SH+N ++GHVD+GK+ +DK R E EA ++G Sbjct: 1 SHMNKDNLRSPICCILGHVDTGKTKL----------LDKIRQTNVQEGEAGGITQQIGAT 50 Query: 53 SFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCA 112 F + K + G KFE + +ID PGH F G+S + A Sbjct: 51 YFPVEAIKQKTAVVNKDG--------KFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIA 102 Query: 113 ILII 116 IL++ Sbjct: 103 ILVV 106 >4V8Y-CP nrPDB Length = 339 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 15/106 (14%) Query: 12 VIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAAELGKGSFKYAWVLDKLKAERERG 70 ++GHVD+GK+ +DK R EA + + + +D +KA+ + Sbjct: 10 ILGHVDTGKTKL----------LDKIRQTNVQGGEAGGITQQIGATYFPIDAIKAKTK-- 57 Query: 71 ITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 + + F+ P + VID PGH F G+S + AIL+I Sbjct: 58 VMAEYEKQTFDVPG--LLVIDTPGHESFSNLRSRGSSLCNIAILVI 101 >1DOD-A nrPDB Length = 394 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 26/53 (49%) Query: 262 VGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVS 314 +GR+ GV++ GMV AGV + + HE +E G ++K +S Sbjct: 40 LGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLS 92 >4N3G-A nrPDB Length = 603 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 31/124 (25%) Query: 6 SHIN--------VVVIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAA----ELGKG 52 SH+N ++GHVD+GK+ +DK R E EA ++G Sbjct: 1 SHMNKDNLRSPICCILGHVDTGKTKL----------LDKIRQTNVQEGEAGGITQQIGAT 50 Query: 53 SFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCA 112 F + K + G KFE + +ID PGH F G+S + A Sbjct: 51 YFPVEAIKQKTAVVNKDG--------KFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIA 102 Query: 113 ILII 116 IL++ Sbjct: 103 ILVV 106 >4GBR-A nrPDB Length = 309 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 343 IVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKK 384 I+LN G +++G++P++ C + F ELL RRS K Sbjct: 253 ILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCL--RRSSLK 292 >3SN6-R nrPDB Length = 514 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 343 IVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKK 384 I+LN G +++G++P++ C + F ELL RRS K Sbjct: 458 ILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCL--RRSSLK 497 >3P0G-A nrPDB Length = 501 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 343 IVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKK 384 I+LN G +++G++P++ C + F ELL RRS K Sbjct: 445 ILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCL--RRSSLK 484 >4FID-A nrPDB Length = 340 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 43/186 (23%), Positives = 70/186 (37%), Gaps = 25/186 (13%) Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 R T I + F +ID G R K ++ S DCAI + + + E++ + Sbjct: 145 RTKTTGIHEYDFVVKDIPFHLIDVGGQRSERKKWVSFFSDVDCAIFVTS--LAEYDMKLY 202 Query: 129 KDGQT----------REHALLAFTLGVRQLIVAVNKMDSV--KWDESRFQEIVKETS--- 173 +DG T ++ F G +LI +NKMD K + I E + Sbjct: 203 EDGNTSRLTESIAVFKDIMTNEFLKGAVKLIF-LNKMDLFEEKLTKVPLNTIFPEYTGGD 261 Query: 174 ------NFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLL 227 +I+++ + ISG +G IE N Y T +K + + Sbjct: 262 NAVMGAQYIQQLFTGKLQTEEMNISGADGTANIEGAVNEKVYTNPTNATDGSNIK-RVFM 320 Query: 228 EAIDAI 233 A+D I Sbjct: 321 LAVDVI 326 >4V8Z-CV nrPDB Length = 586 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Query: 12 VIGHVDSGKSTTTGHLIY------KCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKA 65 ++GHVD+GK+ + + GGI + ++G F +D +KA Sbjct: 10 ILGHVDTGKTKLLDKIRQTNVQGGEAGGITQ-----------QIGATYFP----IDAIKA 54 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 + + + + F+ P + VID PGH F G+S + AIL+I Sbjct: 55 KTK--VMAEYEKQTFDVPG--LLVIDTPGHESFSNLRSRGSSLCNIAILVI 101 >4NCF-A nrPDB Length = 457 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Query: 12 VIGHVDSGKSTTTGHLIY------KCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKA 65 ++GHVD+GK+ + + GGI + ++G F +D +KA Sbjct: 15 ILGHVDTGKTKLLDKIRQTNVQGGEAGGITQ-----------QIGATYFP----IDAIKA 59 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 + + + + F+ P + VID PGH F G+S + AIL+I Sbjct: 60 KTK--VMAEYEKQTFDVPG--LLVIDTPGHESFSNLRSRGSSLCNIAILVI 106 >5U4I-v nrPDB Length = 383 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 10/74 (13%) Query: 228 EAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEV 287 E D I+ P D LR+ DVY+ G G V R E+ V +T P G+ T+ Sbjct: 243 EVDDDIDIEINPAD--LRI---DVYRTSGAGGQHVNRTESAV-----RITHIPTGIVTQC 292 Query: 288 KSVEMHHEQLEQGV 301 ++ H+ +Q + Sbjct: 293 QNDRSQHKNKDQAM 306 >3WBI-A nrPDB Length = 606 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Query: 12 VIGHVDSGKSTTTGHLIY------KCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKA 65 ++GHVD+GK+ + + GGI + ++G F +D +KA Sbjct: 14 ILGHVDTGKTKLLDKIRQTNVQGGEAGGITQ-----------QIGATYFP----IDAIKA 58 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 + + + + F+ P + VID PGH F G+S + AIL+I Sbjct: 59 KTK--VMAEYEKQTFDVPG--LLVIDTPGHESFSNLRSRGSSLCNIAILVI 105 >2R4S-A nrPDB Length = 342 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 343 IVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKK 384 I+LN G +++G++P++ C + F ELL RRS K Sbjct: 286 ILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCL--RRSSLK 325 >5J40-A nrPDB Length = 372 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 25/51 (49%) Query: 14 GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 G +DSGK+T L+ CGG E+ ELG G ++ V + +K Sbjct: 171 GPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVK 221 >3LG8-A nrPDB Length = 106 Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 140 AFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISG 193 A +LG +LIV +NK D D+S + KE N KKV K P V I+G Sbjct: 17 AISLGGGELIVRLNKRDMELIDDSTLWNLEKEVENATKKVTVLKKGEP-VDIAG 69 >4TN1-B nrPDB Length = 345 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 79 KFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 KFE + +ID PGH F G+S + AIL++ Sbjct: 69 KFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIAILVV 106 >4UJC-AB nrPDB Length = 627 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 37/142 (26%) Query: 87 VTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVR 146 + +ID PGH F G+S D AIL++ + G+ + QT E L + Sbjct: 105 MLIIDTPGHESFSNLRNRGSSLCDIAILVV-----DIMHGL--EPQTIESINLLKSKKC- 156 Query: 147 QLIVAVNKMDSV-KWDES------------------RFQEIVKETSNFIKKVGYN----- 182 IVA+NK+D + W +S F+E K + G N Sbjct: 157 PFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFY 216 Query: 183 ----PKT-VPFVPISGWNGDNM 199 P+T V VP S GD M Sbjct: 217 ENKDPRTFVSLVPTSAHTGDGM 238 >2CXX-A nrPDB Length = 190 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 37/176 (21%) Query: 47 AELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGH----------- 95 + +GK + Y K++ + G+T I +++ K +ID PG Sbjct: 10 SNVGKSTLIYRLTGKKVRRGKRPGVTRKIIEIEWKNHK----IIDMPGFGFMMGLPKEVQ 65 Query: 96 ---RDFIKNMITGTSQ-ADCAILIIAGGVG-EFEAGISKDGQTREHALLAFTLGVRQL-- 148 +D I + I ++ D A+L++ G E K G+ + F +R+L Sbjct: 66 ERIKDEIVHFIEDNAKNIDVAVLVVDGKAAPEIIKRWEKRGEI--PIDVEFYQFLRELDI 123 Query: 149 --IVAVNKMDSVKWDESRFQEIVKETSNFIK---KVGYNPKTVPFVPISGWNGDNM 199 IVAVNK+D +K V+E NF+ +V + F+PIS GDN+ Sbjct: 124 PTIVAVNKLDKIKN--------VQEVINFLAEKFEVPLSEIDKVFIPISAKFGDNI 171 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2B7C-A nrPDB 600 e-172 4C0S-A nrPDB 572 e-163 5LZS-jj nrPDB 569 e-163 3WXM-A nrPDB 507 e-144 1JNY-A nrPDB 498 e-141 5LZY-jj nrPDB 464 e-131 5LZT-jj nrPDB 462 e-130 4D61-i nrPDB 460 e-130 3WY9-A nrPDB 456 e-128 1R5O-A nrPDB 433 e-122 4CRN-P nrPDB 410 e-115 4ZV4-A nrPDB 405 e-113 4V5G-AZ nrPDB 405 e-113 5W75-A nrPDB 393 e-109 4J0Q-A nrPDB 388 e-108 3MMP-A nrPDB 388 e-108 5W76-A nrPDB 383 e-107 6MIJ-A nrPDB 383 e-107 3MCA-A nrPDB 379 e-105 1EFM-A nrPDB 371 e-103 5W7Q-A nrPDB 370 e-103 1MJ1-A nrPDB 364 e-101 1D2E-A nrPDB 359 1e-99 1ZUN-B nrPDB 352 2e-97 3IZQ-1 nrPDB 342 2e-94 3P27-A nrPDB 340 7e-94 2HDN-B nrPDB 337 4e-93 5LZD-z nrPDB 251 5e-67 4AC9-A nrPDB 228 5e-60 5I4Q-C nrPDB 222 2e-58 5HXB-X nrPDB 215 4e-56 2YWH-A nrPDB 213 1e-55 4ZU9-A nrPDB 213 1e-55 5IZL-A nrPDB 211 4e-55 2D74-A nrPDB 198 6e-51 5A9Z-CA nrPDB 187 8e-48 5J8B-z nrPDB 184 5e-47 5IMR-C nrPDB 184 7e-47 1S0U-A nrPDB 171 5e-43 3WNB-A nrPDB 168 4e-42 3PEN-A nrPDB 164 8e-41 3CB4-D nrPDB 161 5e-40 5VH6-A nrPDB 160 1e-39 6BK7-A nrPDB 158 4e-39 5G06-P nrPDB 155 3e-38 4ZKD-A nrPDB 155 3e-38 6NOT-A nrPDB 155 5e-38 5KCS-1w nrPDB 152 4e-37 5TY0-A nrPDB 151 4e-37 6N0I-A nrPDB 151 6e-37 4V6V-A1 nrPDB 149 3e-36 6B8D-A nrPDB 148 6e-36 4WQY-BZ nrPDB 148 6e-36 6FEC-S nrPDB 147 8e-36 4FN5-A nrPDB 147 8e-36 3TR5-A nrPDB 147 8e-36 6O81-S nrPDB 146 1e-35 3ZZ0-A nrPDB 143 1e-34 5H7K-A nrPDB 143 2e-34 4V7D-BZ nrPDB 142 3e-34 5H7J-A nrPDB 141 5e-34 5TV2-A nrPDB 140 9e-34 3J81-k nrPDB 140 1e-33 3VQT-A nrPDB 139 3e-33 4V89-AW nrPDB 136 2e-32 6GB2-BC nrPDB 132 3e-31 3IZY-P nrPDB 121 5e-28 4V6W-Az nrPDB 120 1e-27 3J4J-A nrPDB 118 5e-27 4KJZ-A nrPDB 118 5e-27 4B44-A nrPDB 117 1e-26 2P8Y-T nrPDB 116 2e-26 2LKD-A nrPDB 114 6e-26 1WDT-A nrPDB 102 3e-22 Sequences not found previously or not previously below threshold: 1ZO1-I nrPDB 106 3e-23 3JCN-b nrPDB 103 1e-22 6MTD-v nrPDB 101 6e-22 5FG3-A nrPDB 88 7e-18 5YT0-A nrPDB 87 2e-17 1G7S-A nrPDB 86 2e-17 6ID0-C nrPDB 86 2e-17 3JB9-B nrPDB 86 4e-17 4UJC-AB nrPDB 81 8e-16 4NCL-A nrPDB 79 3e-15 4N3G-A nrPDB 78 1e-14 4TN1-B nrPDB 74 1e-13 4V8Y-CP nrPDB 72 5e-13 4NCF-A nrPDB 72 5e-13 3WBI-A nrPDB 71 9e-13 4V8Z-CV nrPDB 69 3e-12 2QTH-A nrPDB 55 6e-08 4DCU-A nrPDB 49 5e-06 3IEU-A nrPDB 48 7e-06 3J8G-X nrPDB 48 1e-05 2WIC-A nrPDB 46 3e-05 5DN8-A nrPDB 46 3e-05 2E87-A nrPDB 46 5e-05 4R98-A nrPDB 46 5e-05 3R9W-A nrPDB 45 6e-05 5FV0-A nrPDB 43 2e-04 5KH0-A nrPDB 42 6e-04 1MKY-A nrPDB 42 7e-04 4V0N-A nrPDB 41 0.001 2CXX-A nrPDB 38 0.009 5WDR-A nrPDB 38 0.010 4ARZ-A nrPDB 37 0.018 2QU8-A nrPDB 37 0.018 1WF3-A nrPDB 36 0.029 1YR7-A nrPDB 36 0.029 5X4B-A nrPDB 36 0.038 3GEH-A nrPDB 36 0.042 3PIR-A nrPDB 36 0.047 1UDX-A nrPDB 36 0.050 3K53-A nrPDB 35 0.074 1XZP-A nrPDB 35 0.083 3JAJ-z nrPDB 35 0.089 6FRK-x nrPDB 34 0.090 5L3Q-A nrPDB 34 0.12 5J40-A nrPDB 34 0.12 5VAI-A nrPDB 34 0.14 5LAD-A nrPDB 34 0.15 2WJG-A nrPDB 34 0.17 2KE5-A nrPDB 34 0.17 6GDG-D nrPDB 34 0.18 4ZI3-A nrPDB 33 0.22 2ERY-A nrPDB 33 0.22 1JGC-A nrPDB 33 0.31 4HI0-E nrPDB 33 0.33 5YMX-A nrPDB 33 0.34 4GDF-A nrPDB 33 0.38 1SVL-A nrPDB 33 0.38 2WJI-A nrPDB 33 0.39 6HA8-V nrPDB 33 0.44 3T1O-A nrPDB 33 0.44 3BH6-A nrPDB 32 0.55 5CM8-B nrPDB 32 0.65 5G41-A nrPDB 32 0.70 5X6J-A nrPDB 32 0.71 4MIT-A nrPDB 32 0.71 4V7F-o nrPDB 32 0.71 5EE0-A nrPDB 32 0.74 4WED-A nrPDB 32 0.74 5DE3-A nrPDB 32 0.76 3IBY-A nrPDB 31 0.82 3CON-A nrPDB 31 0.92 3NXS-A nrPDB 31 1.1 5IRR-A nrPDB 31 1.1 5UHV-A nrPDB 31 1.3 3N05-A nrPDB 31 1.4 3A1U-A nrPDB 31 1.4 3IIK-A nrPDB 31 1.5 4PHF-A nrPDB 31 1.5 2QSZ-A nrPDB 31 1.7 3Q72-A nrPDB 31 1.7 5G3Y-A nrPDB 30 1.7 2FN4-A nrPDB 30 1.7 4WA7-A nrPDB 30 1.8 1Z22-A nrPDB 30 1.8 4M9Q-A nrPDB 30 1.9 5DI3-B nrPDB 30 1.9 2ZOY-A nrPDB 30 1.9 4QBG-B nrPDB 30 2.1 1F6B-A nrPDB 30 2.3 4MKI-B nrPDB 30 2.3 4FID-A nrPDB 30 2.5 4MKG-A nrPDB 30 2.6 1VIA-A nrPDB 29 3.1 6N8J-m nrPDB 29 3.3 4M8N-E nrPDB 29 3.8 4DXA-A nrPDB 29 3.8 3A1W-A nrPDB 29 3.8 1U0L-A nrPDB 29 3.9 4HUQ-A nrPDB 29 4.5 6FT6-s nrPDB 29 4.7 2P3S-A nrPDB 29 5.1 2P65-A nrPDB 29 5.2 5JRH-A nrPDB 28 7.0 3TRF-A nrPDB 28 7.4 1XRT-A nrPDB 28 9.9 >2B7C-A nrPDB Length = 458 Score = 600 bits (1546), Expect = e-172, Method: Composition-based stats. Identities = 458/458 (100%), Positives = 458/458 (100%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL Sbjct: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV Sbjct: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG Sbjct: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT Sbjct: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG Sbjct: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD Sbjct: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG Sbjct: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 Query: 421 RFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK 458 RFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK Sbjct: 421 RFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK 458 >4C0S-A nrPDB Length = 463 Score = 572 bits (1473), Expect = e-163, Method: Composition-based stats. Identities = 366/460 (79%), Positives = 413/460 (89%), Gaps = 3/460 (0%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 MGKEK+HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAE+GKGSFKYAWVL Sbjct: 1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 DKLKAERERGITIDI+LWKFET KY +T+IDAPGHRDFIKNMITGTSQADCA+LI+A GV Sbjct: 61 DKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV 120 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEIVKETSNFIKK 178 GEFEAGISK+GQTREHALLA+TLGV+QLIV VNKMDS + + E R+ EIVKE S +IKK Sbjct: 121 GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKK 180 Query: 179 VGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 +GYNP TVPFVPISGW+GDNM+E + N PW+KGW+ E K G G +LLEA+D I P+R Sbjct: 181 IGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTR 240 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE 298 PTDKPLRLPLQDVYKIGGIGTVPVGRVETG+++PGMVVTFAP +TTEVKSVEMHHE L Sbjct: 241 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALS 300 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 + +PGDNVGFNVKNVSVK+IRRGNVCGD+K+DPP+ A F + VI+LNHPGQISAGYSPV Sbjct: 301 EALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPV 360 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 +DCHTAHIAC+F EL EK DRRSGKKLED+PK LKSGDAA+V+ VP KPMCVE+FS+YPP Sbjct: 361 IDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPP 420 Query: 419 LGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAK 457 LGRFAVRDMRQTVAVGVIK+V+ K+ A KVTK+AQKA K Sbjct: 421 LGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQK 460 >5LZS-jj nrPDB Length = 462 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 371/460 (80%), Positives = 407/460 (88%), Gaps = 3/460 (0%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 MGKEK+HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAE+GKGSFKYAWVL Sbjct: 1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 DKLKAERERGITIDI+LWKFET KY VT+IDAPGHRDFIKNMITGTSQADCA+LI+A GV Sbjct: 61 DKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV 120 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--VKWDESRFQEIVKETSNFIKK 178 GEFEAGISK+GQTREHALLA+TLGV+QLIV VNKMDS + + R++EIVKE S +IKK Sbjct: 121 GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKK 180 Query: 179 VGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 +GYNP TV FVPISGWNGDNM+E + N PW+KGW+ K G G TLLEA+D I P+R Sbjct: 181 IGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTR 240 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE 298 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGV+KPGMVVTFAP VTTEVKSVEMHHE L Sbjct: 241 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS 300 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 + +PGDNVGFNVKNVSVK++RRGNV GD+KNDPP A F A VI+LNHPGQISAGY+PV Sbjct: 301 EALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPV 360 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 LDCHTAHIAC+F EL EK DRRSGKKLED PKFLKSGDAA+V VP KPMCVE+FS+YPP Sbjct: 361 LDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPP 420 Query: 419 LGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAK 457 LGRFAVRDMRQTVAVGVIK+VD K A KVTK+AQKA K Sbjct: 421 LGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQK 460 >3WXM-A nrPDB Length = 447 Score = 507 bits (1306), Expect = e-144, Method: Composition-based stats. Identities = 239/455 (52%), Positives = 323/455 (70%), Gaps = 19/455 (4%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 EK H+N+VVIGHVD GKST GHL+Y+ G I+++ +++ E++A GK SFK+AW+LDK+ Sbjct: 6 EKPHMNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESFKFAWILDKM 65 Query: 64 KAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEF 123 K ERERGITID+ KFET KY T+IDAPGHRDF+KNMITG SQAD AIL+++ GEF Sbjct: 66 KEERERGITIDLTFMKFETKKYVFTIIDAPGHRDFVKNMITGASQADAAILVVSARKGEF 125 Query: 124 EAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--VKWDESRFQEIVKETSNFIKKVGY 181 EAG+S +GQTREH LLA T+G+ Q+IVAVNKMD+ V +D+ R++ +V F+K +GY Sbjct: 126 EAGMSTEGQTREHLLLARTMGIEQIIVAVNKMDAPDVNYDQKRYEFVVSVLKKFMKGLGY 185 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 +PF+P+S W GDN+IE + N PWY G TL+EA+D ++ P++P D Sbjct: 186 QVDKIPFIPVSAWKGDNLIERSPNMPWYN------------GPTLVEALDQLQPPAKPVD 233 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 KPLR+P+Q+VY I G GTVPVGRVETGV++ G V F P GV EV+S+EMH++QL+Q Sbjct: 234 KPLRIPVQNVYSIPGAGTVPVGRVETGVLRVGDKVVFMPPGVVGEVRSIEMHYQQLQQAE 293 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PGDN+GF V+ VS +I+RG+V G PP F A + V+ HP I+ GY+PV+ Sbjct: 294 PGDNIGFAVRGVSKSDIKRGDVAGHLDK-PPTVAEEFEARIFVIWHPSAITVGYTPVIHV 352 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HTA ++ R E+ K D ++G+ +E +P+FLK+GDAA+V+F P KP+ VE FSE P LGR Sbjct: 353 HTASVSSRIIEIKAKLDPKTGQVVEQNPQFLKAGDAAIVRFKPVKPLVVEKFSEIPQLGR 412 Query: 422 FAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAA 456 FA+RDM +TV +G++ V K AKV A+ A Sbjct: 413 FAMRDMNRTVGIGIVTDV----KPAKVDIKAKLAR 443 >1JNY-A nrPDB Length = 435 Score = 498 bits (1281), Expect = e-141, Method: Composition-based stats. Identities = 234/450 (52%), Positives = 316/450 (70%), Gaps = 19/450 (4%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 +K H+N++VIGHVD GKST G L+ G ID++T+++ E+ A +LGK S K+A++LD+L Sbjct: 3 QKPHLNLIVIGHVDHGKSTLVGRLLMDRGFIDEKTVKEAEEAAKKLGKESEKFAFLLDRL 62 Query: 64 KAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEF 123 K ERERG+TI++ +FET KY T+IDAPGHRDF+KNMITG SQAD AIL+++ GE+ Sbjct: 63 KEERERGVTINLTFMRFETKKYFFTIIDAPGHRDFVKNMITGASQADAAILVVSAKKGEY 122 Query: 124 EAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--VKWDESRFQEIVKETSNFIKKVGY 181 EAG+S +GQTREH +LA T+G+ QLIVAVNKMD +DE R++EIV + S F++ G+ Sbjct: 123 EAGMSVEGQTREHIILAKTMGLDQLIVAVNKMDLTEPPYDEKRYKEIVDQVSKFMRSYGF 182 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 N V FVP+ +GDN+ + N WY G TL E +D +E P +P D Sbjct: 183 NTNKVRFVPVVAPSGDNITHKSENMKWYN------------GPTLEEYLDQLELPPKPVD 230 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 KPLR+P+QDVY I G+GTVPVGRVE+GV+K G + F PAG EV+S+E HH ++++ Sbjct: 231 KPLRIPIQDVYSISGVGTVPVGRVESGVLKVGDKIVFMPAGKVGEVRSIETHHTKMDKAE 290 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PGDN+GFNV+ V K+I+RG+V G N PP F A +IV+ HP ++ GY+PVL Sbjct: 291 PGDNIGFNVRGVEKKDIKRGDVVGHPNN-PPTVADEFTARIIVVWHPTALANGYTPVLHV 349 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HTA +ACR EL+ K D R+G++ E +P+FLK GD A+VKF P KP+CVE ++E+PPLGR Sbjct: 350 HTASVACRVSELVSKLDPRTGQEAEKNPQFLKQGDVAIVKFKPIKPLCVEKYNEFPPLGR 409 Query: 422 FAVRDMRQTVAVGVIKSVDKTEKAAKVTKA 451 FA+RDM +TV VG+I V K AKV Sbjct: 410 FAMRDMGKTVGVGIIVDV----KPAKVEIK 435 >5LZY-jj nrPDB Length = 710 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 176/437 (40%), Positives = 257/437 (58%), Gaps = 10/437 (2%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K +N+VVIGHVD+GKST GH++Y G I+KRT+ K+E+E+ + GK SF YAWVLD+ Sbjct: 284 KQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETG 343 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ERERG+T+D+ + KFET +T++DAPGH+DFI NMITG +QAD A+L++ GEFE Sbjct: 344 EERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFE 403 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPK 184 AG GQTREH LL +LGV QL VAVNKMD V W + RFQEI + +F+K+ G+ Sbjct: 404 AGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKES 463 Query: 185 TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPL 244 V F+P SG +G+N+I + ++ K + KG LLE ID+ + P R DKP Sbjct: 464 DVGFIPTSGLSGENLITRSQSSELTKWY---------KGLCLLEQIDSFKPPQRSIDKPF 514 Query: 245 RLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGD 304 RL + DV+K G G G++E G I+ G + P T VK + +H E ++ GD Sbjct: 515 RLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAAGD 574 Query: 305 NVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTA 364 +V + + + +I G + K P K C F A +++ N I+ G+ +L T Sbjct: 575 HVSLTLVGMDIIKINVGCIFCGPK-VPIKACTRFRARILIFNIEIPITKGFPVLLHYQTV 633 Query: 365 HIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAV 424 L+ ++ +G+ + PKFL G ALV+ +P+ +E + ++ LGRF + Sbjct: 634 SEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFML 693 Query: 425 RDMRQTVAVGVIKSVDK 441 R T+A GV+ + + Sbjct: 694 RYGGSTIAAGVVTEIKE 710 >5LZT-jj nrPDB Length = 637 Score = 462 bits (1187), Expect = e-130, Method: Composition-based stats. Identities = 165/441 (37%), Positives = 254/441 (57%), Gaps = 18/441 (4%) Query: 2 GKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLD 61 +K H+NVV IGHVD+GKST G ++Y G +DKRT+EK+E+EA E + ++ +W LD Sbjct: 207 APKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALD 266 Query: 62 KLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVG 121 + ER++G T+++ FET K T++DAPGH+ F+ NMI G SQAD A+L+I+ G Sbjct: 267 TNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKG 326 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKV 179 EFE G K GQTREHA+LA T GV+ LIV +NKMD +V W R++E ++ F+KKV Sbjct: 327 EFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKV 386 Query: 180 GYNP-KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 G+NP K + F+P SG G N+ E + PWY G + +D + +R Sbjct: 387 GFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGL------------PFIPYLDNLPNFNR 434 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE 298 D P+RLP+ D YK +GTV +G++E+G I G + P EV + + + Sbjct: 435 SVDGPIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETD 492 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 PG+N+ +K + +EI G + D N G +F+A ++++ H I GY+ V Sbjct: 493 TVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSG-RTFDAQIVIIEHKSIICPGYNAV 551 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 L HT L+ D++SG+K + P+F+K + + + +C+E F ++P Sbjct: 552 LHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQ 611 Query: 419 LGRFAVRDMRQTVAVGVIKSV 439 +GRF +RD +T+A+G + + Sbjct: 612 MGRFTLRDEGKTIAIGKVLKL 632 >4D61-i nrPDB Length = 426 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 165/438 (37%), Positives = 253/438 (57%), Gaps = 18/438 (4%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+NVV IGHVD+GKST G ++Y G +DKRT+EK+E+EA E + ++ +W LD + Sbjct: 1 KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQ 60 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER++G T+++ FET K T++DAPGH+ F+ NMI G SQAD A+L+I+ GEFE Sbjct: 61 EERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFE 120 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKVGYN 182 G K GQTREHA+LA T GV+ LIV +NKMD +V W R++E ++ F+KKVG+N Sbjct: 121 TGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFN 180 Query: 183 P-KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 P K + F+P SG G N+ E + PWY G + +D + +R D Sbjct: 181 PKKDIHFMPCSGLTGANLKEQSDFCPWYIGL------------PFIPYLDNLPNFNRSVD 228 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGV 301 P+RLP+ D YK +GTV +G++E+G I G + P EV + + + Sbjct: 229 GPIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVA 286 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDC 361 PG+N+ +K + +EI G + D N G +F+A ++++ H I GY+ VL Sbjct: 287 PGENLKIRLKGIEEEEILPGFILCDPNNLCHSG-RTFDAQIVIIEHKSIICPGYNAVLHI 345 Query: 362 HTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGR 421 HT L+ D++SG+K + P+F+K + + + +C+E F ++P +GR Sbjct: 346 HTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGR 405 Query: 422 FAVRDMRQTVAVGVIKSV 439 F +RD +T+A+G + + Sbjct: 406 FTLRDEGKTIAIGKVLKL 423 >3WY9-A nrPDB Length = 434 Score = 456 bits (1173), Expect = e-128, Method: Composition-based stats. Identities = 231/451 (51%), Positives = 305/451 (67%), Gaps = 31/451 (6%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M KEK H+N+V IGHVD GKSTT G L+Y G I + I+KFE E E GK SFK+AWV+ Sbjct: 1 MPKEKPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFE-EMGEKGK-SFKFAWVM 58 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 D+LK ERERGITID+A KFETP +T+IDAPGHRDF+KNMITG SQAD A+L++A Sbjct: 59 DRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAATD 118 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 G QT+EHA LA TLG++ +IV +NKMD V +D+ F+++ + +K +G Sbjct: 119 GVMP-------QTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLKTLG 171 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 Y K P +P S WNGDN+++ + PWY G TL+EA+D I +P +P Sbjct: 172 Y--KDFPVIPTSAWNGDNVVKKSDKMPWYN------------GPTLIEALDQIPEPEKPI 217 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAG------VTTEVKSVEMHH 294 DKPLR+P+QDVY I G+GTVPVGRVETG +K G VV F PA + EVKS+EMHH Sbjct: 218 DKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPASTIFHKPIQGEVKSIEMHH 277 Query: 295 EQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDP--PKGCASFNATVIVLNHPGQIS 352 E L++ +PGDN+GFNV+ VS +I+RG+V G P + +F A +IVLNHP I+ Sbjct: 278 EPLQEALPGDNIGFNVRGVSKNDIKRGDVAGHTDKPPTVVRTKDTFKAQIIVLNHPTAIT 337 Query: 353 AGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEA 412 GYSPVL HTA I RF+++L K D R+G +E++P+F+K+GD+A+V P KP+ +E Sbjct: 338 VGYSPVLHAHTAQIPVRFEQILAKVDPRTGNIVEENPQFIKTGDSAIVVLRPMKPVVLEP 397 Query: 413 FSEYPPLGRFAVRDMRQTVAVGVIKSVDKTE 443 E P LGRFA+RDM T+A G++ S+ K E Sbjct: 398 VKEIPQLGRFAIRDMGMTIAAGMVISIQKGE 428 >1R5O-A nrPDB Length = 467 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 167/442 (37%), Positives = 253/442 (57%), Gaps = 24/442 (5%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+N+V IGHVD+GKST G++++ G +DKRT+EK E+EA E GK S+ +W LD Sbjct: 41 KEHVNIVFIGHVDAGKSTLGGNILFLTGMVDKRTMEKIEREAKEAGKESWYLSWALDSTS 100 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ERE+G T+++ FET + +++DAPGH+ ++ NMI G SQAD +L+I+ GEFE Sbjct: 101 EEREKGKTVEVGRAYFETEHRRFSLLDAPGHKGYVTNMINGASQADIGVLVISARRGEFE 160 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKV-GY 181 AG + GQTREHA+LA T G+ L+V +NKMD SV+W E R++E V + S F+++V GY Sbjct: 161 AGFERGGQTREHAVLARTQGINHLVVVINKMDEPSVQWSEERYKECVDKLSMFLRRVAGY 220 Query: 182 NPKT-VPFVPISGWNGDNMIEATTN--APWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 N KT V ++P+S + G N+ + + PWY+ G +LLE +D++ R Sbjct: 221 NSKTDVKYMPVSAYTGQNVKDRVDSSVCPWYQ------------GPSLLEYLDSMTHLER 268 Query: 239 PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSV-EMHHEQL 297 + P +P+ YK +GT+ G++E G IK V P T EV ++ + E++ Sbjct: 269 KVNAPFIMPIASKYK--DLGTILEGKIEAGSIKKNSNVLVMPINQTLEVTAIYDEADEEI 326 Query: 298 EQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSP 357 + GD V V+ +++ G V KN P F A + +L P ++ GYS Sbjct: 327 SSSICGDQVRLRVRG-DDSDVQTGYVLTSTKN-PVHATTRFIAQIAILELPSILTTGYSC 384 Query: 358 VLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYP 417 V+ HTA F +LL K D+ + +K + P F G + + P+C+E F +Y Sbjct: 385 VMHIHTAVEEVSFAKLLHKLDK-TNRKSKKPPMFATKGMKIIAELETQTPVCMERFEDYQ 443 Query: 418 PLGRFAVRDMRQTVAVGVIKSV 439 +GRF +RD TVAVG + + Sbjct: 444 YMGRFTLRDQGTTVAVGKVVKI 465 >4CRN-P nrPDB Length = 430 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 165/443 (37%), Positives = 253/443 (57%), Gaps = 21/443 (4%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H++++ +GHVD+GKST G+L+Y G +DKRTIEK+E+EA + G+ + +WV+D K Sbjct: 3 KDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNK 62 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER G TI++ FET K + T++DAPGH+ ++ MI G SQAD +L+I+ GE+E Sbjct: 63 EERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYE 122 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD--SVKWDESRFQEIVKETSNFIKKVGYN 182 G + GQTREHALLA T GV +++V VNKMD +V W + R+ + V SNF++ +GYN Sbjct: 123 TGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYN 182 Query: 183 PKT-VPFVPISGWNGDNMIEATT--NAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRP 239 KT V F+P+SG++G N+ + PWY G TLLE +D + R Sbjct: 183 IKTDVVFMPVSGYSGANLKDHVDPKECPWY------------TGPTLLEYLDTMNHVDRH 230 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHE-QLE 298 + P LP+ K+ +GT+ G++E+G IK G P E++++ E +++ Sbjct: 231 INAPFMLPI--AAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVD 288 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 + G+ V +K V ++I G V KN P K F A + ++ I+AG+S V Sbjct: 289 MAMCGEQVKLRIKGVEEEDISPGFVLTSPKN-PIKSVTKFVAQIAIVELKSIIAAGFSCV 347 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + HTA +LL K ++ + +K + P F K G + P+CVE + +YP Sbjct: 348 MHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQ 407 Query: 419 LGRFAVRDMRQTVAVGVIKSVDK 441 LGRF +RD T+A+G I + + Sbjct: 408 LGRFTLRDQGTTIAIGKIVKIAE 430 >4ZV4-A nrPDB Length = 405 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 123/444 (27%), Positives = 194/444 (43%), Gaps = 55/444 (12%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T L C ++ GS + +D Sbjct: 8 RNKPHVNVGTIGHVDHGKTTLTAALTKVC---------------SDTWGGSARAFDQIDN 52 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 E+ RGITI+ + ++++ +D PGH D++KNMITG +Q D AIL+ + G Sbjct: 53 APEEKARGITINTSHVEYDSAVRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGP 112 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LL+ +GV ++V +NK D V D + + E + + + Sbjct: 113 MP-------QTREHILLSRQVGVPYIVVFLNKADMVD-DAELLELVEMEVRDLLNTYDFP 164 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTD 241 P + S + + GV + L+E +D+ I +P R D Sbjct: 165 GDDTPIIIGSAL-------------MALEGKDDNGIGVSAVQKLVETLDSYIPEPVRAID 211 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQ 299 +P +P++DV+ I G GTV GRVE G+IK V T T VEM + L++ Sbjct: 212 QPFLMPIEDVFSISGRGTVVTGRVERGIIKVQEEVEIVGIKATTKTTCTGVEMFRKLLDE 271 Query: 300 GVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVL 359 G G+NVG ++ +++ RG V AK K F V VL+ + ++P Sbjct: 272 GRAGENVGILLRGTKREDVERGQVL--AKPGTIKPHTKFECEVYVLSK--EEGGRHTPFF 327 Query: 360 DCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPL 419 + R D +L + + + GD + P+ +E Sbjct: 328 KGYRPQFYFR------TTDVTGNCELPEGVEMVMPGDNIKMVVTLIAPIAMEDGL----- 376 Query: 420 GRFAVRDMRQTVAVGVIKSVDKTE 443 RFA+R+ +TV GV+ + + E Sbjct: 377 -RFAIREGGRTVGAGVVAKIIELE 399 >4V5G-AZ nrPDB Length = 406 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 144/443 (32%), Positives = 203/443 (45%), Gaps = 48/443 (10%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T L Y AAE K +DK Sbjct: 8 RTKPHVNVGTIGHVDHGKTTLTAALTYVA--------------AAENPNVEVKDYGDIDK 53 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 ER RGITI+ A ++ET K + +D PGH D+IKNMITG +Q D AIL+++ G Sbjct: 54 APEERARGITINTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGAILVVSAADGP 113 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LLA +GV ++V +NK+D V D + E + + + + Sbjct: 114 MP-------QTREHILLARQVGVPYIVVFMNKVDMVD-DPELLDLVEMEVRDLLNQYEFP 165 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTD 241 VP + S +E P + E E V K LL+AID I P R D Sbjct: 166 GDEVPVIRGSALLA---LEQMHRNPKTRRGENEW---VDKIWELLDAIDEYIPTPVRDVD 219 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA---PAGVTTEVKSVEMHHEQLE 298 KP +P++DV+ I G GTV GR+E G +K G V P T V VEMH + L+ Sbjct: 220 KPFLMPVEDVFTITGRGTVATGRIERGKVKVGDEVEIVGLAPETRRTVVTGVEMHRKTLQ 279 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 +G+ GDNVG ++ VS +E+ RG V + P F A+V VL + ++ Sbjct: 280 EGIAGDNVGVLLRGVSREEVERGQVLAKPGSITPH--TKFEASVYVLKK--EEGGRHTGF 335 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + R D +L + + GD KP+ +E Sbjct: 336 FSGYRPQFYFR------TTDVTGVVQLPPGVEMVMPGDNVTFTVELIKPVALEEGL---- 385 Query: 419 LGRFAVRDMRQTVAVGVIKSVDK 441 RFA+R+ +TV GV+ + + Sbjct: 386 --RFAIREGGRTVGAGVVTKILE 406 >5W75-A nrPDB Length = 392 Score = 393 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 135/443 (30%), Positives = 193/443 (43%), Gaps = 55/443 (12%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 K H+NV IGHVD GKST T + G + +DK Sbjct: 1 TKPHVNVGTIGHVDHGKSTLTAAITKYLSL---------------KGLAQYVPYDQIDKA 45 Query: 64 KAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEF 123 E+ RGITI+I ++ET K ID PGH D+IKNMITG +Q D AIL++A G Sbjct: 46 PEEKARGITINITHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAATDGPM 105 Query: 124 EAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNP 183 QTREH LLA +GV +IV +NK D V D + + E + + + Y Sbjct: 106 P-------QTREHVLLARQVGVPYMIVFINKTDMVD-DPELIELVEMEVRDLLSQYEYPG 157 Query: 184 KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTDK 242 VP + S + + + LL+A+D I P R DK Sbjct: 158 DEVPVIKGSALKA------------LEAPDDPNHEAYKPIQELLDAMDNYIPDPQRDVDK 205 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAG---VTTEVKSVEMHHEQLEQ 299 P +P++DV+ I G GTV GR+E G I+PG V T V SVEM ++L++ Sbjct: 206 PFLMPIEDVFSITGRGTVVTGRIERGRIRPGDEVEIIGLSYEIRKTVVTSVEMFRKELDE 265 Query: 300 GVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVL 359 G+ GDNVG ++ + E+ RG V + K F A V VL + ++P Sbjct: 266 GIAGDNVGCLLRGIDKDEVERGQVLAAPGS--IKPHKRFKAEVYVLKK--EEGGRHTPFF 321 Query: 360 DCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPL 419 + R D L + + + GD ++ P+ +E Sbjct: 322 KGYKPQFYIR------TTDVTGEIVLPEGVEMVMPGDHVEMEIELIYPVAIEKGQ----- 370 Query: 420 GRFAVRDMRQTVAVGVIKSVDKT 442 RFA+R+ +TV GV+ V + Sbjct: 371 -RFAIREGGRTVGAGVVTEVIEL 392 >4J0Q-A nrPDB Length = 433 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 121/449 (26%), Positives = 193/449 (42%), Gaps = 60/449 (13%) Query: 1 MGKEK-----SHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFK 55 M KEK H+NV IGHVD GK+T T L C + I +F+K Sbjct: 37 MAKEKFDRSLPHVNVGTIGHVDHGKTTLTAALTRVCSEVFGSAIVEFDK----------- 85 Query: 56 YAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILI 115 +D E+ RGITI+ A ++ + +D PGH D++KNMITG +Q D AIL+ Sbjct: 86 ----IDSAPEEKARGITINTAHVEYNSTIRHYAHVDCPGHADYVKNMITGAAQMDGAILV 141 Query: 116 IAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNF 175 + G QTREH LL+ +GV ++V +NK D V D + + E + Sbjct: 142 CSAADGPMP-------QTREHILLSRQVGVPYIVVFLNKADLVD-DAELLELVEMEVRDL 193 Query: 176 IKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IE 234 + + P + S + + + G K L+E +D+ I Sbjct: 194 LSTYDFPGDDTPIIIGSA-------------RMALEGKDDNEMGTTAVKKLVETLDSYIP 240 Query: 235 QPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGV--TTEVKSVEM 292 +P R D+P +P++DV+ I G GTV GR+E G+++ + TT VEM Sbjct: 241 EPVRAIDQPFLMPIEDVFSISGRGTVVTGRIERGIVRVQDPLEIVGLRDTTTTTCTGVEM 300 Query: 293 HHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQIS 352 + L++G G+N G ++ ++ RG V + K F A V VL+ + Sbjct: 301 FRKLLDEGRAGENCGVLLRGTKRDDVERGQVLVKPGS--VKPHTKFTAEVYVLSK--EEG 356 Query: 353 AGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEA 412 ++P + R D +L + + + GD + K + +E Sbjct: 357 GRHTPFFKGYRPQFYFR------TTDVTGNCELPEGVEMVMPGDNIQMTVTLIKTIAMED 410 Query: 413 FSEYPPLGRFAVRDMRQTVAVGVIKSVDK 441 RFA+R+ +TV GV+ + + Sbjct: 411 GL------RFAIREGGRTVGAGVVAKIIE 433 >3MMP-A nrPDB Length = 678 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 126/439 (28%), Positives = 194/439 (44%), Gaps = 56/439 (12%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T + A+ G+ + +D Sbjct: 292 RTKPHVNVGTIGHVDHGKTTLTAAITTVL---------------AKTYGGAARAFDQIDN 336 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 E+ RGITI+ + +++TP +D PGH D++KNMITG +Q D AIL++A G Sbjct: 337 APEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGP 396 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LL +GV +IV +NK D + DE + + E + + + Sbjct: 397 MP-------QTREHILLGRQVGVPYIIVFLNKCD-MVDDEELLELVEMEVRELLSQYDFP 448 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDK 242 P V S + E +A +++ L++ I +P R DK Sbjct: 449 GDDTPIVRGSALKA-------------LEGDAEWEAKILELAGFLDSY--IPEPERAIDK 493 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQG 300 P LP++DV+ I G GTV GRVE G+IK G V T + VEM + L++G Sbjct: 494 PFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEG 553 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 G+NVG ++ + +EI RG V AK K F + V +L+ ++P Sbjct: 554 RAGENVGVLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILSK--DEGGRHTPFFK 609 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 + R D +L + + + GD + P+ ++ Sbjct: 610 GYRPQFYFR------TTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL------ 657 Query: 421 RFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ V Sbjct: 658 RFAIREGGRTVGAGVVAKV 676 >5W76-A nrPDB Length = 385 Score = 383 bits (984), Expect = e-107, Method: Composition-based stats. Identities = 127/441 (28%), Positives = 195/441 (44%), Gaps = 59/441 (13%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 K H+N+ IGHVD GK+T T + K AE G+ FK +DK Sbjct: 1 TKPHVNIGTIGHVDHGKTTLTAAIT---------------KVLAEKGQAEFKAYDQIDKA 45 Query: 64 KAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEF 123 E+ERGITI A ++ET +D PGH D++KNMITG +Q D AIL+++ G Sbjct: 46 PEEKERGITISTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPM 105 Query: 124 EAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNP 183 QTREH LLA +GV ++V +NK+D + DE + + E + + Sbjct: 106 P-------QTREHILLARQVGVPYIVVFLNKVD-MVDDEELLELVEMEVRELLSSYDFPG 157 Query: 184 KTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTDK 242 +P + S + + G L++A+D+ I +P R DK Sbjct: 158 DDIPIIKGSALKA----------------LEGDEEGEEAIMKLMDAVDSYIPEPERAIDK 201 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQG 300 P +P++DV+ I GTV GRVE G++K G V T T VEM + L++G Sbjct: 202 PFLMPIEDVFSIS-RGTVVTGRVERGIVKVGEEVEIVGIRDTQKTTCTGVEMFRKLLDEG 260 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 GDNVG ++ +++ RG V + K F A V +L + ++P + Sbjct: 261 QAGDNVGVLLRGTKREDVERGQVLAKPGS--IKPHTKFKAEVYILTK--EEGGRHTPFFN 316 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 + R D L + + + GD + P+ +E Sbjct: 317 GYRPQFYFR------TTDVTGVITLPEGVEMVMPGDNVTITVELIAPIAMEEGL------ 364 Query: 421 RFAVRDMRQTVAVGVIKSVDK 441 RFA+R+ +TV GV+ + + Sbjct: 365 RFAIREGGRTVGAGVVSEIIE 385 >6MIJ-A nrPDB Length = 396 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 128/440 (29%), Positives = 195/440 (44%), Gaps = 56/440 (12%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T + C A+ G K +D Sbjct: 8 RNKPHVNVGTIGHVDHGKTTLTAAIATIC---------------AKTYGGEAKDYSQIDS 52 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 E+ RGITI+ + ++++P +D PGH D++KNMITG +Q D AIL+ A G Sbjct: 53 APEEKARGITINTSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGP 112 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LL+ +GV +IV +NK + DE + + E + + Sbjct: 113 MP-------QTREHILLSRQVGVPYIIVFLNKC-DLVDDEELLELVEMEVRELLSTYDFP 164 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTD 241 P + S N + G L+ A+D+ I +P R D Sbjct: 165 GDDTPVIRGSALAALN--------------GEAGPYGEESVLALVAALDSYIPEPERAID 210 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQ 299 K +P++DV+ I G GTV GRVE G+IK G V T T V VEM + L++ Sbjct: 211 KAFLMPIEDVFSISGRGTVVTGRVEAGIIKVGEEVEIVGIKDTVKTTVTGVEMFRKLLDE 270 Query: 300 GVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVL 359 G G+N G ++ +E++RG V AK K F+A V VL+ + ++P L Sbjct: 271 GRAGENCGILLRGTKREEVQRGQVL--AKPGTIKPHTKFDAEVYVLSK--EEGGRHTPFL 326 Query: 360 DCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPL 419 + + R D +L++ + + GD + P+ ++ Sbjct: 327 NGYRPQFYFR------TTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMDPGL----- 375 Query: 420 GRFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ V Sbjct: 376 -RFAIREGGRTVGAGVVAKV 394 >3MCA-A nrPDB Length = 592 Score = 379 bits (973), Expect = e-105, Method: Composition-based stats. Identities = 164/442 (37%), Positives = 243/442 (54%), Gaps = 32/442 (7%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K +++VV GHVDSGKST G ++++ G I+ R+++K EAA GKGSF YAW+LD + Sbjct: 175 KPVVHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTE 234 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER RG+T+D+A FE+ K + DAPGHRDFI MI G S AD A+L++ FE Sbjct: 235 EERARGVTMDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFE 294 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFI-KKVGYNP 183 G ++GQTREHA L LG+ +++V+VNK+D + W E RFQEI S+F+ K VG+ Sbjct: 295 RGFLENGQTREHAYLLRALGISEIVVSVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKT 354 Query: 184 KTVPFVPISGWNGDNMIEATTN--APWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTD 241 V FVPIS +G N+I+ ++ WY KG TLL A+D + P +P Sbjct: 355 SNVHFVPISAISGTNLIQKDSSDLYKWY------------KGPTLLSALDQLVPPEKPYR 402 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLE-QG 300 KPLRL + DVY+ TV GRVE G ++ V+ + VK+V + + Sbjct: 403 KPLRLSIDDVYRSPRSVTV-TGRVEAGNVQVNQVLYDVSSQEDAYVKNVIRNSDPSSTWA 461 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 V GD V + ++ V ++R G++ + +N P + SF A + + G I +G + VL Sbjct: 462 VAGDTVTLQLADIEVNQLRPGDILSNYEN-PVRRVRSFVAEIQTFDIHGPILSGSTLVLH 520 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSK---PMCVEAFSEYP 417 + +++ N++RS + + S ALV+ P+C+ E P Sbjct: 521 LGRTVTSVSL-KIVTVNNKRS--------RHIASRKRALVRISFLDGLFPLCLA--EECP 569 Query: 418 PLGRFAVRDMRQTVAVGVIKSV 439 LGRF +R TVA G++K + Sbjct: 570 ALGRFILRRSGDTVAAGIVKEL 591 >1EFM-A nrPDB Length = 379 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 125/439 (28%), Positives = 188/439 (42%), Gaps = 70/439 (15%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T + VL K Sbjct: 7 RTKPHVNVGTIGHVDHGKTTLTAAIT-----------------------------TVLAK 37 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 RGITI+ + +++TP +D PGH D++KNMITG +Q D AIL++A G Sbjct: 38 TYGGAARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGP 97 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LL +GV +IV +NK D + DE + + E + + + Sbjct: 98 MP-------QTREHILLGRQVGVPYIIVFLNKCD-MVDDEELLELVEMEVRELLSQYDFP 149 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDK 242 P V S + E +A +++ L++ I +P R DK Sbjct: 150 GDDTPIVRGSALKA-------------LEGDAEWEAKILELAGFLDSY--IPEPERAIDK 194 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQG 300 P LP++DV+ I G GTV GRVE G+IK G V T + VEM + L++G Sbjct: 195 PFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEG 254 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 G+NVG ++ + +EI RG V AK K F + V +L+ ++P Sbjct: 255 RAGENVGVLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILSK--DEGGRHTPFFK 310 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 + R D +L + + + GD + P+ ++ Sbjct: 311 GYRPQFYFR------TTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL------ 358 Query: 421 RFAVRDMRQTVAVGVIKSV 439 RFA+R+ +TV GV+ V Sbjct: 359 RFAIREGGRTVGAGVVAKV 377 >5W7Q-A nrPDB Length = 373 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 122/441 (27%), Positives = 188/441 (42%), Gaps = 71/441 (16%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+N+ IGHVD GK+T T + A+ G K +D Sbjct: 1 RTKPHVNIGTIGHVDHGKTTLTAAITTVL---------------AKKGGAEAKAYDQIDN 45 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 E+ RGITI+ A ++ET +D PGH D++KNMITG +Q D AIL+++ G Sbjct: 46 APEEKARGITINTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGP 105 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LLA +GV ++V +NK D + DE + + E + + + Sbjct: 106 MP-------QTREHILLARQVGVPYIVVFLNKCD-MVDDEELLELVEMEVRELLSEYDFP 157 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTD 241 +P + G + +A W K L++A+D+ I P R D Sbjct: 158 GDDIPII-----RGSALKALEGDAEWE-----------DKILELMDAVDSYIPTPERDID 201 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQ 299 KP +P++DV+ I G GTV GRVE G++K G V T T V VEM Sbjct: 202 KPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIKDTQKTTVTGVEM------- 254 Query: 300 GVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVL 359 VG ++ +++ RG V + P F A V VL+ + ++P Sbjct: 255 ------VGALLRGTKREDVERGQVLAKPGSITPH--TKFEAEVYVLSK--EEGGRHTPFF 304 Query: 360 DCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPL 419 + + R D +L + + + GD + P+ +E Sbjct: 305 NGYRPQFYFR------TTDVTGVIELPEGVEMVMPGDNVKMTVELIAPIAMEEGL----- 353 Query: 420 GRFAVRDMRQTVAVGVIKSVD 440 RFA+R+ +TV GV+ + Sbjct: 354 -RFAIREGGRTVGAGVVSKII 373 >1MJ1-A nrPDB Length = 405 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 135/443 (30%), Positives = 196/443 (44%), Gaps = 48/443 (10%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 + K H+NV IGHVD GK+T T L Y AAE K +DK Sbjct: 7 RTKRHVNVGTIGHVDHGKTTLTAALTYVA--------------AAENRNVEVKDYGDIDK 52 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 + ER RGITI+ A ++ET K + +D GH D+IKNMITG +Q D AIL+++ G Sbjct: 53 AREERARGITINTAHVEYETAKRHYSHVDCRGHADYIKNMITGAAQMDGAILVVSAADGR 112 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 QTREH LLA +GVR ++V +NK+D V D + E + + + + Sbjct: 113 MR-------QTREHILLARQVGVRYIVVFMNKVDMVD-DRELLDLVEMEVRDLLNQYEFR 164 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTD 241 V + S A + ++ V K LL+AID I R D Sbjct: 165 GDEVRVIRGSALL------ALEEMHKNRKTKRGENEWVDKIWELLDAIDEYIRTRVRDVD 218 Query: 242 KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTE---VKSVEMHHEQLE 298 K + ++DV+ I G GTV GR+E G +K G V T V VEMH + L+ Sbjct: 219 KRFLMRVEDVFTITGRGTVATGRIERGKVKVGDEVEIVGLARETRKTVVTGVEMHRKTLQ 278 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPV 358 +G+ GDNVG ++ VS +E+ RG V AK F A+V +L + ++ Sbjct: 279 EGIAGDNVGLLLRGVSREEVERGQVL--AKRGSITRHTKFEASVYILKK--EEGGRHTGF 334 Query: 359 LDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPP 418 + R D +L + + GD K + +E Sbjct: 335 FTGYRRQFYFR------TTDVTGVVRLRQGVEMVMRGDNVTFTVELIKRVALEEGL---- 384 Query: 419 LGRFAVRDMRQTVAVGVIKSVDK 441 RFA+R+ +TV GV+ + + Sbjct: 385 --RFAIREGGRTVGAGVVTKILE 405 >1D2E-A nrPDB Length = 397 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 129/442 (29%), Positives = 195/442 (44%), Gaps = 66/442 (14%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K H+NV IGHVD GK+T T + K AE G FK +D Sbjct: 1 KPHVNVGTIGHVDHGKTTLTAAIT---------------KILAEGGGAKFKKYEEIDNAP 45 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ER RGITI+ A ++ T D PGH D++KNMITGT+ D IL++A G Sbjct: 46 EERARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMP 105 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPK 184 QTREH LLA +GV ++V VNK D+V+ D + + E + + GY + Sbjct: 106 -------QTREHLLLARQIGVEHVVVYVNKADAVQ-DSEMVELVELEIRELLTEFGYKGE 157 Query: 185 TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-IEQPSRPTDKP 243 P + S +++ + G+ + LL+A+D I P+R +KP Sbjct: 158 ETPIIVGSALCALE--------------QRDPELGLKSVQKLLDAVDTYIPVPTRDLEKP 203 Query: 244 LRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA--PAGVTTEVKSVEMHHEQLEQGV 301 LP++ VY I G GTV G +E G++K G F + T V +EM H+ L++ Sbjct: 204 FLLPVESVYSIPGRGTVVTGTLERGILKKGDECEFLGHSKNIRTVVTGIEMFHKSLDRAE 263 Query: 302 PGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNH-----PGQISAGYS 356 GDN+G V+ + +++RRG V + P A V +L + + Sbjct: 264 AGDNLGALVRGLKREDLRRGLVMAKPGSIQPHQ--KVEAQVYILTKEEGGRHKPFVSHFM 321 Query: 357 PVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEY 416 PV+ T +ACR L + G+ + + +PM +E Sbjct: 322 PVMFSLTWDMACRI-------------ILPPGKELAMPGEDLKLTLILRQPMILEKGQ-- 366 Query: 417 PPLGRFAVRDMRQTVAVGVIKS 438 RF +RD +T+ G++ Sbjct: 367 ----RFTLRDGNRTIGTGLVTD 384 >1ZUN-B nrPDB Length = 434 Score = 352 bits (903), Expect = 2e-97, Method: Composition-based stats. Identities = 124/439 (28%), Positives = 212/439 (48%), Gaps = 31/439 (7%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKG--SFKYAWVL 60 + K + + G+VD GKST G L++ I + +E +++ + G A ++ Sbjct: 20 ERKEMLRFLTCGNVDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKSGTTGDDVDLALLV 79 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 D L+AERE+GITID+A F T K + + D PGH + +NM TG S D AI+++ Sbjct: 80 DGLQAEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILVDARY 139 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 G QTR H+ +A LG++ ++VA+NKMD +DE F+ I + F + + Sbjct: 140 GV-------QTQTRRHSYIASLLGIKHIVVAINKMDLNGFDERVFESIKADYLKFAEGIA 192 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPT 240 + P T+ FVP+S GDN++ + +PWY G++L+E ++ +E S Sbjct: 193 FKPTTMAFVPMSALKGDNVVNKSERSPWY------------AGQSLMEILETVEIASDRN 240 Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 LR P+Q V + G + +G++ G + P+G ++ VKS+ +LEQ Sbjct: 241 YTDLRFPVQYVNRPNLNFRGFAGTLASGIVHKGDEIVVLPSGKSSRVKSIVTFEGELEQA 300 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 PG V ++ +I RG++ A N P + +F+A ++ + + G + Sbjct: 301 GPGQAVTLTME--DEIDISRGDLLVHADNVP-QVSDAFDAMLVWMAEEPML-PGKKYDIK 356 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHP-KFLKSGDAALVKFVPSKPMCVEAFSEYPPL 419 T+++ + + D + LE+ P L+ + VK P+ ++ +S Sbjct: 357 RATSYVPGSIASITHRVDVNT---LEEGPASSLQLNEIGRVKVSLDAPIALDGYSSNRTT 413 Query: 420 GRFAVRD--MRQTVAVGVI 436 G F V D TVA G+I Sbjct: 414 GAFIVIDRLTNGTVAAGMI 432 >3IZQ-1 nrPDB Length = 611 Score = 342 bits (877), Expect = 2e-94, Method: Composition-based stats. Identities = 136/465 (29%), Positives = 221/465 (47%), Gaps = 48/465 (10%) Query: 6 SHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKA 65 H++ VV+GHVD+GKST G L+Y +++ + K ++E+ +GK SFK+AW++D+ Sbjct: 166 PHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNE 225 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEA 125 ERERG+T+ I F T + T++DAPGHRDF+ N I G SQAD AIL + FE+ Sbjct: 226 ERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFES 285 Query: 126 GISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKT 185 G DGQT+EH LLA +LG+ LI+A+NKMD+V W + RF+EI + ++ +G+ Sbjct: 286 GFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDN 345 Query: 186 VPFVPISG------------------WNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLL 227 + +VPISG +NG N++ NA + E E G+ K L Sbjct: 346 INWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENE---GINKDDPFL 402 Query: 228 EAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEV 287 ++ I PS+ T L L G++E+G I+PG +T P+ + V Sbjct: 403 FSVLEI-IPSKKTSNDLAL--------------VSGKLESGSIQPGESLTIYPSEQSCIV 447 Query: 288 KSVE--------MHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFN 339 ++ +HE+ + + GD V ++ ++I+ G++ F Sbjct: 448 DKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFV 507 Query: 340 ATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAAL 399 + + + G +L R L+ D+ + + L S A Sbjct: 508 LELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDK-GNTASKKKIRHLGSKQRAF 566 Query: 400 VKFVPS---KPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDK 441 V+ + + + E LGR +R +T+A G I + + Sbjct: 567 VEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ 611 >3P27-A nrPDB Length = 483 Score = 340 bits (872), Expect = 7e-94, Method: Composition-based stats. Identities = 136/465 (29%), Positives = 221/465 (47%), Gaps = 48/465 (10%) Query: 6 SHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKA 65 H++ VV+GHVD+GKST G L+Y +++ + K ++E+ +GK SFK+AW++D+ Sbjct: 32 PHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNE 91 Query: 66 ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEA 125 ERERG+T+ I F T + T++DAPGHRDF+ N I G SQAD AIL + FE+ Sbjct: 92 ERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFES 151 Query: 126 GISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKT 185 G DGQT+EH LLA +LG+ LI+A+NKMD+V W + RF+EI + ++ +G+ Sbjct: 152 GFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDN 211 Query: 186 VPFVPISG------------------WNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLL 227 + +VPISG +NG N++ NA + E E G+ K L Sbjct: 212 INWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENE---GINKDDPFL 268 Query: 228 EAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEV 287 ++ I PS+ T L L G++E+G I+PG +T P+ + V Sbjct: 269 FSVLEI-IPSKKTSNDLAL--------------VSGKLESGSIQPGESLTIYPSEQSCIV 313 Query: 288 KSVE--------MHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFN 339 ++ +HE+ + + GD V ++ ++I+ G++ F Sbjct: 314 DKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFV 373 Query: 340 ATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAAL 399 + + + G +L R L+ D+ + + L S A Sbjct: 374 LELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDK-GNTASKKKIRHLGSKQRAF 432 Query: 400 VKFVPS---KPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDK 441 V+ + + + E LGR +R +T+A G I + + Sbjct: 433 VEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ 477 >2HDN-B nrPDB Length = 335 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 108/372 (29%), Positives = 167/372 (44%), Gaps = 41/372 (11%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GITI+ + +++TP +D PGH D++KNMITG +Q D AIL++A G Sbjct: 1 GITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMP----- 55 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QTREH LL +GV +IV +NK D + DE + + E + + + P V Sbjct: 56 --QTREHILLGRQVGVPYIIVFLNKCD-MVDDEELLELVEMEVRELLSQYDFPGDDTPIV 112 Query: 190 PISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQ 249 S + E +A +++ L++ I +P R DKP LP++ Sbjct: 113 RGSALKA-------------LEGDAEWEAKILELAGFLDSY--IPEPERAIDKPFLLPIE 157 Query: 250 DVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT--TEVKSVEMHHEQLEQGVPGDNVG 307 DV+ I G GTV GRVE G+IK G V T + VEM + L++G G+NVG Sbjct: 158 DVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVG 217 Query: 308 FNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIA 367 ++ + +EI RG V AK K F + V +L+ ++P + Sbjct: 218 VLLRGIKREEIERGQVL--AKPGTIKPHTKFESEVYILSK--DEGGRHTPFFKGYRPQFY 273 Query: 368 CRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDM 427 R D +L + + + GD + P+ ++ RFA+R+ Sbjct: 274 FR------TTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL------RFAIREG 321 Query: 428 RQTVAVGVIKSV 439 +TV GV+ V Sbjct: 322 GRTVGAGVVAKV 333 >5LZD-z nrPDB Length = 614 Score = 251 bits (640), Expect = 5e-67, Method: Composition-based stats. Identities = 77/400 (19%), Positives = 144/400 (36%), Gaps = 76/400 (19%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 + GHVD GK+T + D+L E++R Sbjct: 3 IATAGHVDHGKTTLLQAIT----------------------------GVNADRLPEEKKR 34 Query: 70 GITIDIALWKFETPKYQVT-VIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 G+TID+ + P +V ID PGH F+ NM+ G D A+L++A G Sbjct: 35 GMTIDLGYAYWPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVM----- 89 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 QTREH + G L VA+ K D V DE+R E+ ++ +++ G+ + Sbjct: 90 --AQTREHLAILQLTGNPMLTVALTKADRV--DEARVDEVERQVKEVLREYGFAEAKLFI 145 Query: 189 VPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPL 248 + G + L E + + + + RL + Sbjct: 146 TAATEGRGMD--------------------------ALREHLLQLPEREHASQHSFRLAI 179 Query: 249 QDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGF 308 + + G G V G +G +K G + V+++ ++ E G + Sbjct: 180 DRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIAL 239 Query: 309 NVKN-VSVKEIRRGN-VCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHI 366 N+ ++I RG+ + D +P F ++ L ++ + +H+ Sbjct: 240 NIAGDAEKEQINRGDWLLADVPPEP------FTRVIVELQTHTPLTQWQPLHIHHAASHV 293 Query: 367 ACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSK 406 R + + + D P +L D +++ + ++ Sbjct: 294 TGRV----SLLEDNLAELVFDTPLWLADNDRLVLRDISAR 329 >4AC9-A nrPDB Length = 482 Score = 228 bits (580), Expect = 5e-60, Method: Composition-based stats. Identities = 85/356 (23%), Positives = 150/356 (42%), Gaps = 60/356 (16%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 +IN+ + GH+D GK+T + L DKL Sbjct: 19 NINLGIFGHIDHGKTTLSKVLTEIAS------------------------TSAHDKLPES 54 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 ++RGITIDI F+ Y++T++DAPGH D I+ +++ D A++++ G Sbjct: 55 QKRGITIDIGFSAFKLENYRITLVDAPGHADLIRAVVSAADIIDLALIVVDAKEGP---- 110 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 QT EH L+ + +IV + K D+ +E + E++ ++ I + +N K Sbjct: 111 ---KTQTGEHMLILDHFNIP-IIVVITKSDNAGTEEIKRTEMIMKS---ILQSTHNLKNS 163 Query: 187 PFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRL 246 +PIS G GV + K L+ + R T+ ++ Sbjct: 164 SIIPISAKTG---------------------FGVDELKNLIITTLNNAEIIRNTESYFKM 202 Query: 247 PLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNV 306 PL + I G GTV G + G++K G + P ++T+V+S++ E + + GD V Sbjct: 203 PLDHAFPIKGAGTVVTGTINKGIVKVGDELKVLPINMSTKVRSIQYFKESVMEAKAGDRV 262 Query: 307 GFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCH 362 G ++ V K+I RG + K+ + A + + + +P + H Sbjct: 263 GMAIQGVDAKQIYRGCILTS-KDTKLQTVDKIVAKIKISD---IFKYNLTPKMKVH 314 >5I4Q-C nrPDB Length = 217 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 64/231 (27%), Positives = 103/231 (44%), Gaps = 20/231 (8%) Query: 211 GWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVI 270 + E +A +++ L++ I +P R DKP LP++DV+ I G GTV GRVE G+I Sbjct: 3 EGDAEWEAKILELAGFLDSY--IPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGII 60 Query: 271 KPGMVVTFAPAGVT--TEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAK 328 K G V T + VEM + L++G G+NVG ++ + +EI RG V AK Sbjct: 61 KVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVL--AK 118 Query: 329 NDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDH 388 K F + V +L+ ++P + R D +L + Sbjct: 119 PGTIKPHTKFESEVYILSK--DEGGRHTPFFKGYRPQFYFR------TTDVTGTIELPEG 170 Query: 389 PKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSV 439 + + GD + P+ ++ RFA+R+ +TV GV+ V Sbjct: 171 VEMVMPGDNIKMVVTLIHPIAMDDGL------RFAIREGGRTVGAGVVAKV 215 >5HXB-X nrPDB Length = 199 Score = 215 bits (546), Expect = 4e-56, Method: Composition-based stats. Identities = 58/199 (29%), Positives = 103/199 (51%), Gaps = 3/199 (1%) Query: 241 DKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQG 300 P+RLP+ D YK +GTV +G++E+G I G + P EV + + + Sbjct: 2 SGPIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTV 59 Query: 301 VPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLD 360 PG+N+ +K + +EI G + D N G +F+A ++++ H I GY+ VL Sbjct: 60 APGENLKIRLKGIEEEEILPGFILCDPNNLCHSG-RTFDAQIVIIEHKSIICPGYNAVLH 118 Query: 361 CHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLG 420 HT L+ D++SG+K + P+F+K + + + +C+E F ++P +G Sbjct: 119 IHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMG 178 Query: 421 RFAVRDMRQTVAVGVIKSV 439 RF +RD +T+A+G + + Sbjct: 179 RFTLRDEGKTIAIGKVLKL 197 >2YWH-A nrPDB Length = 600 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 79/345 (22%), Positives = 134/345 (38%), Gaps = 63/345 (18%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 ++K+ N +I HVD GKST L+ G I +R + +LD Sbjct: 2 EQKNVRNFCIIAHVDHGKSTLADRLLEYTGAISEREKREQ----------------LLDT 45 Query: 63 LKAERERGITIDIALWKF-----ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 L ERERGIT+ + + + Y++ +ID PGH DF + + + A+L+I Sbjct: 46 LDVERERGITVKMQAVRMFYKAKDGNTYKLHLIDTPGHVDFSYEVSRALAACEGALLLID 105 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIK 177 G ++ + E L+ +I +NK+D D R ++ ++E Sbjct: 106 ASQGIEAQTVANFWKAVEQDLV--------IIPVINKIDLPSADVDRVKKQIEEVL---- 153 Query: 178 KVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPS 237 G + + I A+ K G+ + L ++ I P Sbjct: 154 ---------------GLDPEEAILAS------------AKEGIGIEEILEAIVNRIPPPK 186 Query: 238 RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQL 297 KPL+ + D Y G V R+ G +KPG + G EV V ++ Sbjct: 187 GDPQKPLKALIFDSYYDPYRGAVAFVRIFDGEVKPGDKIMLMSTGKEYEVTEVGAQTPKM 246 Query: 298 EQ--GVPGDNVGFNVKNV-SVKEIRRGNVCGDAKNDPPKGCASFN 339 + + +VG+ ++ V++IR G+ AKN + F Sbjct: 247 TKFDKLSAGDVGYIAASIKDVRDIRIGDTITHAKNPTKEPVPGFQ 291 >4ZU9-A nrPDB Length = 582 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 86/393 (21%), Positives = 150/393 (38%), Gaps = 75/393 (19%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 GHVD GK+T L D+L E++R Sbjct: 6 FATAGHVDHGKTTLIKTLT----------------------------GIDTDRLPEEKKR 37 Query: 70 GITIDIALWKFETPKY--QVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 G++IDI + P ++ +ID PGH FIKN I G A IL++ G Sbjct: 38 GLSIDIGFAYIDFPDINTRLEIIDVPGHERFIKNAIAGICSASGLILVVDPNEGIMP--- 94 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 QT EH +A + G++ I + KMD V + + E +E F++K N + V Sbjct: 95 ----QTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAE--EELIAFLEKEEMNMEIVK 148 Query: 188 FVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLP 247 ++G +++ K LLE+I+ + + KPLR+ Sbjct: 149 VSAVTGQGIEDLK--------------------NSIKKLLESINNLNK-----HKPLRIF 183 Query: 248 LQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVG 307 + + + G GTV G G +K G V P GV + V+ ++ H +++ V G+ + Sbjct: 184 VDSAFVVKGYGTVLRGSCFEGEVKEGDKVVVEPIGVISRVRKMQNHGVFVKKAVAGERIA 243 Query: 308 FNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIA 367 N+ V K+++RG + ++ + V+++ + G + Sbjct: 244 LNLPEVDAKKVKRGFLILKPESYE-------KSNVLIVKTEIDLKPGKIYQVFFGMRETV 296 Query: 368 CRFDELLEKNDRRSGKKLEDHPKFLKSGDAALV 400 + D+ ++ GD +V Sbjct: 297 GKI----SVIDKGIYLVRLKENAIVRRGDKLVV 325 >5IZL-A nrPDB Length = 616 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 92/380 (24%), Positives = 142/380 (37%), Gaps = 79/380 (20%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M + ++NV V+GH+DSGK+ L + Sbjct: 21 MAGRRVNVNVGVLGHIDSGKTALARAL------------------------STTASTAAF 56 Query: 61 DKLKAERERGITIDIALWKFETPK-------------------------YQVTVIDAPGH 95 DK RERGIT+D+ F P QVT++D PGH Sbjct: 57 DKQPQSRERGITLDLGFSCFSVPLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGH 116 Query: 96 RDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKM 155 I+ +I G D +L+I G Q+ E L+ + ++L+V +NK+ Sbjct: 117 ASLIRTIIGGAQIIDLMMLVIDVTKGM-------QTQSAEC-LVIGQIACQKLVVVLNKI 168 Query: 156 DSVKWDESRFQEIVKETSNFIKKVGYNPK--TVPFVPISGWNGDNMIEATTNAPWYKGWE 213 D + E + Q + + + ++K N K P +P++ G AP E Sbjct: 169 DLLP--EGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGG------PEAP-----E 215 Query: 214 KETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPG 273 E G+ + LL + I P+R P + + + I G GTV G + +G I G Sbjct: 216 TEAPQGIPELIELLTS--QISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLG 273 Query: 274 MVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPK 333 V V +VKS++M H + + GD +G V K + RG VC P Sbjct: 274 DSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCA-----PES 328 Query: 334 GCASFNATVIVLNHPGQISA 353 A + V P Sbjct: 329 LHTVHAALISVEKIPYFRGP 348 >2D74-A nrPDB Length = 419 Score = 198 bits (502), Expect = 6e-51, Method: Composition-based stats. Identities = 99/485 (20%), Positives = 166/485 (34%), Gaps = 125/485 (25%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 ++ +N+ ++GHVD GK+T T L D Sbjct: 7 TRQAEVNIGMVGHVDHGKTTLTKALT----------------------------GVWTDT 38 Query: 63 LKAERERGITIDIALWKFETPK-----------------------YQVTVIDAPGHRDFI 99 E RGITI I E + +V+ ID+PGH + Sbjct: 39 HSEELRRGITIKIGFADAEIRRCSNCGRYSTSPICPYCGHETEFIRRVSFIDSPGHEALM 98 Query: 100 KNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVK 159 M+ G S D AIL+IA QTREH + +G + +I+A NK++ V Sbjct: 99 TTMLAGASLMDGAILVIAANEP------CPRPQTREHLMALQIIGQKNIIIAQNKIELV- 151 Query: 160 WDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAG 219 D+ + E ++ FIK G + P +PIS +G N+ Sbjct: 152 -DKEKALENYRQIKEFIK--GTVAENAPIIPISALHGANI-------------------- 188 Query: 220 VVKGKTLLEAIDA-IEQPSRPTDKPLRLPLQDVYKIGGIGT--------VPVGRVETGVI 270 L++AI+ I P R ++KP ++ + + + GT V G + G + Sbjct: 189 ----DVLVKAIEEFIPTPKRDSNKPPKMLVLRSFDVNKPGTPPEKLVGGVLDGSIVQGKL 244 Query: 271 KPGMVVTFAP------------AGVTTEVKSVEMHHEQLEQGVPGDNVGFNVK---NVSV 315 K G + P +TTE+ S++ + +E+ PG VG K ++ Sbjct: 245 KVGDEIEIRPGVPYEEHGRIKYEPITTEIVSLQAGGQFVEEAYPGGLVGIGTKLDPYLTK 304 Query: 316 KEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLE 375 ++ GNV G PP V +L + + Sbjct: 305 GDLMAGNVVGKPGKLPP-VWTDLRLEVHLLER-------------VVGTEQELNVEPIKR 350 Query: 376 KNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGV 435 K + + ++ P+C E + R + + G+ Sbjct: 351 KEVLLLNVGTARTMGLVTALGKDEIELKLQIPVCAEPGERVAISRQIGSRW--RLIGYGI 408 Query: 436 IKSVD 440 IK ++ Sbjct: 409 IKELE 413 >5A9Z-CA nrPDB Length = 593 Score = 187 bits (475), Expect = 8e-48, Method: Composition-based stats. Identities = 70/332 (21%), Positives = 118/332 (35%), Gaps = 55/332 (16%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 N+ +I HVD GK+T L+ + G D R + V+D E+ Sbjct: 6 RNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQER---------------VMDSNDLEK 50 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 ERGITI Y++ ++D PGH DF + S D +L++ G Sbjct: 51 ERGITILAKNTAAIKWDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMP--- 107 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 QTR AF G++ IV +NK+D R +V + + + + + Sbjct: 108 ----QTRFVTKKAFAYGLKP-IVVINKVDRPGA---RPDWVVDQVFDLFVNLDATDEQLD 159 Query: 188 FVPI--SGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLR 245 F + S NG ++ A +D + P D P + Sbjct: 160 FAIVYASALNGIAGLDHEDMAE-------------DMTPLYQAIVDHVPAPDVDLDGPFQ 206 Query: 246 LPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSV-------EMHHEQLE 298 + + + +G + +GR++ G +KP VT + T V + + + Sbjct: 207 MQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETD 266 Query: 299 QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKND 330 GD V E+ + D +N Sbjct: 267 LAEAGDIVAIT-------ELNISDTVCDTQNV 291 >5J8B-z nrPDB Length = 679 Score = 184 bits (467), Expect = 5e-47, Method: Composition-based stats. Identities = 69/341 (20%), Positives = 115/341 (33%), Gaps = 64/341 (18%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 N +I HVD GKST ++ + R + + LD L+ ER Sbjct: 79 RNFSIIAHVDHGKSTLADRILELTHAVSDREMREQ----------------FLDSLELER 122 Query: 68 ERGITIDIALWKF-----ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 ERGITI + + + +Y +ID PGH DF + + + +L++ G Sbjct: 123 ERGITIKASAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGV 182 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 ++K EH + +I +NK+D V+E Sbjct: 183 EAETLAKFYMALEHGHV--------IIPVINKIDLPNARPLEVALEVEEVL--------- 225 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDK 242 G D I A+ K G + L + I P + Sbjct: 226 ----------GLPADEAIFASG------------KTGEGVEEILEAIVQRIPPPKGDPEA 263 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQ---LEQ 299 PL+ + D G +P R+ G ++PG + G V V + Q + Sbjct: 264 PLKALIFDSVYDAYQGVIPYLRLFEGRVRPGDRIRIYSTGKEFTVDKVGVFTPQGLVATE 323 Query: 300 GVPGDNVGFNVKNV-SVKEIRRGNVCGDAKNDPPKGCASFN 339 + VG+ V + + +++ G+ A P F Sbjct: 324 ALEAGEVGWLVAAIRDIHDVQVGDTITLADRPTPSPYPGFR 364 >5IMR-C nrPDB Length = 610 Score = 184 bits (467), Expect = 7e-47, Method: Composition-based stats. Identities = 69/341 (20%), Positives = 115/341 (33%), Gaps = 64/341 (18%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 N +I HVD GKST ++ + R + + LD L+ ER Sbjct: 10 RNFSIIAHVDHGKSTLADRILELTHAVSDREMREQ----------------FLDSLELER 53 Query: 68 ERGITIDIALWKF-----ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGE 122 ERGITI + + + +Y +ID PGH DF + + + +L++ G Sbjct: 54 ERGITIKASAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGV 113 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 ++K EH + +I +NK+D V+E Sbjct: 114 EAETLAKFYMALEHGHV--------IIPVINKIDLPNARPLEVALEVEEVL--------- 156 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDK 242 G D I A+ K G + L + I P + Sbjct: 157 ----------GLPADEAIFASG------------KTGEGVEEILEAIVQRIPPPKGDPEA 194 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQ---LEQ 299 PL+ + D G +P R+ G ++PG + G V V + Q + Sbjct: 195 PLKALIFDSVYDAYQGVIPYLRLFEGRVRPGDRIRIYSTGKEFTVDKVGVFTPQGLVATE 254 Query: 300 GVPGDNVGFNVKNV-SVKEIRRGNVCGDAKNDPPKGCASFN 339 + VG+ V + + +++ G+ A P F Sbjct: 255 ALEAGEVGWLVAAIRDIHDVQVGDTITLADRPTPSPYPGFR 295 >1S0U-A nrPDB Length = 408 Score = 171 bits (433), Expect = 5e-43, Method: Composition-based stats. Identities = 99/465 (21%), Positives = 167/465 (35%), Gaps = 97/465 (20%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 ++ +N+ ++GHVD GK++ T L G R E+ + S + + +++ Sbjct: 6 QAEVNIGMVGHVDHGKTSLTKAL---TGVWTDRHSEELRRGI------SIRLGYADCEIR 56 Query: 65 AERERGITID-------IALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 + G +A +F +V+ +D+PGH + M++G S D AIL+IA Sbjct: 57 KCPQCGTYTTKPRCPNCLAETEF---LRRVSFVDSPGHETLMATMLSGASLMDGAILVIA 113 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIK 177 QT+EH + LG+ ++I+ NK+D V DE + +E ++ F+K Sbjct: 114 ANEP------CPQPQTKEHLMALEILGIDKIIIVQNKIDLV--DEKQAEENYEQIKEFVK 165 Query: 178 KVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAI-DAIEQP 236 G + P +PIS + N+ LL+AI D I P Sbjct: 166 --GTIAENAPIIPISAHHEANI------------------------DVLLKAIQDFIPTP 199 Query: 237 SRPTDKPLRLPLQDVYKIGGIGT--------VPVGRVETGVIKPGMVVTFAPAGV----- 283 R D R+ + + I GT V G + GV K G + P Sbjct: 200 KRDPDATPRMYVARSFDINKPGTEIKDLKGGVLGGAIIQGVFKVGDEIEIRPGIKVTEGN 259 Query: 284 -------TTEVKSVEMHHEQLEQGVPGDNVGFNV---KNVSVKEIRRGNVCGDAKNDPPK 333 TT++ S+ + L + PG +G ++ + G+V G PP Sbjct: 260 KTFWKPLTTKIVSLAAGNTILRKAHPGGLIGVGTTLDPYLTKSDALTGSVVGLPGTLPP- 318 Query: 334 GCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELL--EKNDRRSGKKLEDHPKF 391 +I+ + + + + L E G Sbjct: 319 -------------IREKITIRANLLDRVVGTKEELKIEPLRTGEVLMLNIGTATTAGVIT 365 Query: 392 LKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVI 436 GD A +K P+C E R R + + G I Sbjct: 366 SARGDIADIKLKL--PICAEIGDRVAISRRVGSRW--RLIGYGTI 406 >3WNB-A nrPDB Length = 370 Score = 168 bits (426), Expect = 4e-42, Method: Composition-based stats. Identities = 72/359 (20%), Positives = 133/359 (37%), Gaps = 49/359 (13%) Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 ++G + DI ++ + + +DA + +K++IT + +D A+L I Sbjct: 43 KKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITALNISDIAVLCIPPQ-------- 94 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 D T E + LG + I+A+ + DS + E +K + TV Sbjct: 95 GLDAHTGECIIALDLLGFKHGIIALTRSDSTHM------HAIDELKAKLKVI--TSGTV- 145 Query: 188 FVPISGWNGDNMIEATTNAPWYKGWE--KETKAGVVKGKTLLEAIDAIEQPSRPTDKPLR 245 + W I TN +E E KA + + +EA + + P R Sbjct: 146 ---LQDW---ECISLNTNKSAKNPFEGVDELKARINEVAEKIEA-----ENAELNSLPAR 194 Query: 246 LPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDN 305 + + + + G G V +G V+ G+ K P E++S++ H ++ G Sbjct: 195 IFIDHAFNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTR 254 Query: 306 VGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAH 365 VG +KNV K+I RG + D + + V +I L Sbjct: 255 VGMRLKNVQAKDIERGFIISDKEIVT----TDYTLECTVSKFTKKIEPASVLHLFVGLQS 310 Query: 366 IACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAV 424 R +++L G ++E+ K G +++ +K + Y RF + Sbjct: 311 EPVRVEKILVD-----GNEVEE----AKPGSTCVLELSGNKKLA------YSKQDRFLL 354 >3PEN-A nrPDB Length = 403 Score = 164 bits (414), Expect = 8e-41, Method: Composition-based stats. Identities = 97/437 (22%), Positives = 158/437 (36%), Gaps = 91/437 (20%) Query: 2 GKEKSHINVVVIGHVDSGKSTT----TGHLIYKCGGIDKRTI---EKFEKEAAELGKGSF 54 K + +N+ V+GHVD GK+T TG K G + I E +K A + + S Sbjct: 3 PKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKKLGYAETNIGVCESCKKPEAYVTEPSC 62 Query: 55 KYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAIL 114 K D+ K R +++ IDAPGH + M++G + D AIL Sbjct: 63 KSCGSDDEPKFLR------------------RISFIDAPGHEVLMATMLSGAALMDGAIL 104 Query: 115 IIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSN 174 ++A QTREH + +GV+ LI+ NK+D V +E+ ++ Sbjct: 105 VVAANEP------FPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEA--LSQYRQIKQ 156 Query: 175 FIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA-I 233 F K G + VP +P+S + N+ +L+E I+ I Sbjct: 157 FTK--GTWAENVPIIPVSALHKINI------------------------DSLIEGIEEYI 190 Query: 234 EQPSRP-TDKPLRLPL--QDVYKIG-----GIGTVPVGRVETGVIKPGMVVTFAPAGVT- 284 + P R + KP+ L + DV K G G V G + G+ K + P Sbjct: 191 KTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVE 250 Query: 285 -----------TEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPK 333 T++ S+ E+ ++ PG V + A N Sbjct: 251 KQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGT-YLDPS-------LTKADNLLGS 302 Query: 334 GCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLK 393 +A V VL + I Y+ + A + D + K + Sbjct: 303 IITLADAEVPVLWN---IRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVT 359 Query: 394 SGDAALVKFVPSKPMCV 410 S ++ +P+ V Sbjct: 360 SVKKDEIEVELRRPVAV 376 >3CB4-D nrPDB Length = 599 Score = 161 bits (407), Expect = 5e-40, Method: Composition-based stats. Identities = 78/346 (22%), Positives = 127/346 (36%), Gaps = 69/346 (19%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K+ N +I H+D GKST + +I CGG+ R +E A VLD + Sbjct: 2 KNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREME----------------AQVLDSMD 45 Query: 65 AERERGITIDIALWKFET-----PKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGG 119 ERERGITI + YQ+ ID PGH DF + + + A+L++ G Sbjct: 46 LERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAG 105 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKV 179 G + QT + A + + +++ +NK+D D R E +++ Sbjct: 106 QGV-------EAQTLANCYTAMEMDL-EVVPVLNKIDLPAADPERVAEEIEDIVGI---- 153 Query: 180 GYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRP 239 V S G V L + I P Sbjct: 154 ----DATDAVRCSAKTG-----------------------VGVQDVLERLVRDIPPPEGD 186 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQL-- 297 + PL+ + D + +G V + R++ G ++ G V G T + + + Sbjct: 187 PEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVD 246 Query: 298 -EQGVPGDNVGFNVKNVSVKEIR---RGNVCGDAKNDPPKGCASFN 339 + G+ VG+ V + K+I G+ A+N K F Sbjct: 247 RTELKCGE-VGWLVCAI--KDIHGAPVGDTLTLARNPAEKALPGFK 289 >5VH6-A nrPDB Length = 409 Score = 160 bits (403), Expect = 1e-39, Method: Composition-based stats. Identities = 55/228 (24%), Positives = 96/228 (42%), Gaps = 30/228 (13%) Query: 1 MGKE---KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M +E + N+ ++ H+D+GK+TTT +++ G I K E +G+ + Sbjct: 4 MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRIHK---------IGETHEGASQMD 54 Query: 58 WVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 W ++ E+ERGITI A + Y+V +ID PGH DF + D A+ ++ Sbjct: 55 W----MEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLD 110 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIK 177 G + QT A T GV + IV VNKMD + D + Sbjct: 111 AQSGV-------EPQTETVWRQATTYGVPR-IVFVNKMDKIGADF------LYSVGTLRD 156 Query: 178 KVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKT 225 ++ N + + N + +I+ N ++ + T++ + Sbjct: 157 RLQANAHAIQLPIGAEDNFEGIIDLVENVAYFYEDDLGTRSDAKEIPE 204 >6BK7-A nrPDB Length = 407 Score = 158 bits (400), Expect = 4e-39, Method: Composition-based stats. Identities = 58/252 (23%), Positives = 100/252 (39%), Gaps = 31/252 (12%) Query: 1 MGKE---KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M +E + N+ ++ HVD+GK+TTT ++Y G I K E +G+ + Sbjct: 4 MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHK---------IGETHEGASQMD 54 Query: 58 WVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 W ++ E+ERGITI A + Y+V +ID PGH DF + D A+ ++ Sbjct: 55 W----MEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLD 110 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIK 177 G + QT A V + IV NKMD + D E + + Sbjct: 111 SQSGV-------EPQTETVWRQATEYKVPR-IVFCNKMDKIGADFFYSVESLHDRL---- 158 Query: 178 KVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAI---DAIE 234 + +P +P + G + + + + + L +A + + Sbjct: 159 QANAHPIQIPIGAEEDFTGIIDLIKMKAEIYTNDLGTDIQETDIPEDYLEKAQEWREKLV 218 Query: 235 QPSRPTDKPLRL 246 + TD+ L + Sbjct: 219 EAVAETDEDLMM 230 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 28/187 (14%), Positives = 58/187 (31%), Gaps = 12/187 (6%) Query: 156 DSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKE 215 D + + +E I++ N + P + S + + Y Sbjct: 227 DLMMKYLEGEEITEEELVAGIRQATINVEFFPVLAGSAFKNKGVQLMLDAVLDYLP---- 282 Query: 216 TKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMV 275 + + K + D + P V +G + RV +GV++ G Sbjct: 283 SPLDIDAIKGIDTKTDEETTRPADDEAPFASLAFKVMTDPFVGRLTFFRVYSGVLESGSY 342 Query: 276 VTFAPAGVTTEV-KSVEMH---HEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDP 331 V A G + + ++MH +++++ GD V +K+ G+ Sbjct: 343 VLNASKGKKERIGRILQMHANTRQEIDKVYSGD----IAAAVGLKDTTTGDTLCALDAPV 398 Query: 332 PKGCASF 338 F Sbjct: 399 ILESIEF 405 >5G06-P nrPDB Length = 747 Score = 155 bits (392), Expect = 3e-38, Method: Composition-based stats. Identities = 79/463 (17%), Positives = 169/463 (36%), Gaps = 78/463 (16%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELG-KGSFKYAWVLDKLKA 65 ++ + +G ++GKST GHL+Y I ++ + +K+++ L S + +LD K Sbjct: 267 NLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKVILDNTKT 326 Query: 66 ERERGITIDIALWKFET----PKYQVTVIDAPGH-RDFIKNMITG--TSQADCAILIIAG 118 ERE G ++ + + E P +T+ID PG + F K + T + +L+I Sbjct: 327 ERENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSILTFDPEVYVLVIDC 386 Query: 119 GVGEFEAGI-SKDGQTREHALLAFTLG-----VRQLIVAVNKMDSVKWDESRFQEIVKET 172 +E + + Q E + L + LI+ +NK D + WD+ R + I E Sbjct: 387 NYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKADLISWDKHRLEMIQSEL 446 Query: 173 SNFIKK-VGYNPKTVPFVPISGWNGDNM--IEATTNAPWYKGWEKETK-AGVVKGKTLLE 228 + +K+ + F+P SG G N+ E T + + ++ +G T Sbjct: 447 NYVLKENFQWTDAEFQFIPCSGLLGSNLNKTENITKSKYKSEFDSINYVPEWYEGPTFFS 506 Query: 229 AI-----DAIEQPSRPTDKPL---------RLPLQDVYKIGGIGTVPVGRVETGVIKPGM 274 + + + ++P P+ ++ + + +G I+ G Sbjct: 507 QLYLLVEHNMNKIETTLEEPFVGTILQSSVLQPIAEINYVSLKVL-----INSGYIQSGQ 561 Query: 275 VVTFAPAGVTTEVKSVEM---HHEQLEQGVPGDNVGFNV--------------KNVSVKE 317 + + + +Q+ + +N+ + ++ + K+ Sbjct: 562 TIEIHTQYEDFHYYGIVSRMKNSKQILETNTKNNISVGLNPDILEVLVKIHNTEDFTKKQ 621 Query: 318 --IRRGNVCGD-------AKNDPPK----GCASFNATVIVLNHPGQISAGYSPVLDCHTA 364 IR+G++ + N P ++ + G +L + Sbjct: 622 FHIRKGDIIIHSRKTNTLSPNLPNTLKLLALRLIKLSIQTHALSDPVDLGSELLLYHNLT 681 Query: 365 HIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKP 407 H A + ++L ND + + +V+ +P Sbjct: 682 HNAVKLVKILGTNDIS-----------INPNQSLIVEVEIIEP 713 >4ZKD-A nrPDB Length = 499 Score = 155 bits (392), Expect = 3e-38, Method: Composition-based stats. Identities = 79/463 (17%), Positives = 169/463 (36%), Gaps = 78/463 (16%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELG-KGSFKYAWVLDKLKA 65 ++ + +G ++GKST GHL+Y I ++ + +K+++ L S + +LD K Sbjct: 19 NLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKVILDNTKT 78 Query: 66 ERERGITIDIALWKFET----PKYQVTVIDAPGH-RDFIKNMITG--TSQADCAILIIAG 118 ERE G ++ + + E P +T+ID PG + F K + T + +L+I Sbjct: 79 ERENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSILTFDPEVYVLVIDC 138 Query: 119 GVGEFEAGI-SKDGQTREHALLAFTLG-----VRQLIVAVNKMDSVKWDESRFQEIVKET 172 +E + + Q E + L + LI+ +NK D + WD+ R + I E Sbjct: 139 NYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKADLISWDKHRLEMIQSEL 198 Query: 173 SNFIKK-VGYNPKTVPFVPISGWNGDNM--IEATTNAPWYKGWEKETK-AGVVKGKTLLE 228 + +K+ + F+P SG G N+ E T + + ++ +G T Sbjct: 199 NYVLKENFQWTDAEFQFIPCSGLLGSNLNKTENITKSKYKSEFDSINYVPEWYEGPTFFS 258 Query: 229 AI-----DAIEQPSRPTDKPL---------RLPLQDVYKIGGIGTVPVGRVETGVIKPGM 274 + + + ++P P+ ++ + + +G I+ G Sbjct: 259 QLYLLVEHNMNKIETTLEEPFVGTILQSSVLQPIAEINYVSLKVL-----INSGYIQSGQ 313 Query: 275 VVTFAPAGVTTEVKSVEM---HHEQLEQGVPGDNVGFNV--------------KNVSVKE 317 + + + +Q+ + +N+ + ++ + K+ Sbjct: 314 TIEIHTQYEDFHYYGIVSRMKNSKQILETNTKNNISVGLNPDILEVLVKIHNTEDFTKKQ 373 Query: 318 --IRRGNVCGD-------AKNDPPK----GCASFNATVIVLNHPGQISAGYSPVLDCHTA 364 IR+G++ + N P ++ + G +L + Sbjct: 374 FHIRKGDIIIHSRKTNTLSPNLPNTLKLLALRLIKLSIQTHALSDPVDLGSELLLYHNLT 433 Query: 365 HIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKP 407 H A + ++L ND + + +V+ +P Sbjct: 434 HNAVKLVKILGTNDIS-----------INPNQSLIVEVEIIEP 465 >6NOT-A nrPDB Length = 707 Score = 155 bits (390), Expect = 5e-38, Method: Composition-based stats. Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 21/171 (12%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 + K + N+ + H+D+GK+TTT ++Y G + E+ +G W Sbjct: 12 INKLEQIRNIGICAHIDAGKTTTTERILYYTGK---------SHKIGEVHEGGATMDW-- 60 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 ++ E+ERGITI A + +ID PGH DF + D A+ + G Sbjct: 61 --MEQEQERGITITSAATTCRWQDKVINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVA 118 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 G + Q+ A V + + VNKMD + D R E++K+ Sbjct: 119 GV-------EPQSETVWRQADKYNVPR-MCFVNKMDRMGADFYRCVEMIKD 161 >5KCS-1w nrPDB Length = 639 Score = 152 bits (383), Expect = 4e-37, Method: Composition-based stats. Identities = 74/357 (20%), Positives = 129/357 (36%), Gaps = 59/357 (16%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 IN+ V+ HVD+GK+T T L+Y G I E + KG+ + D ER Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAIT---------ELGSVDKGTTR----TDNTLLER 50 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +RGITI + F+ +V +ID PGH DF+ + S D AIL+I+ G Sbjct: 51 QRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGV----- 105 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 QTR +G+ I +NK+D D S + +KE + + + P Sbjct: 106 --QAQTRILFHALRKMGIP-TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYP 162 Query: 188 FVPISGWNG-----------DNMIEAT-------------------TNAPWYKGWEKETK 217 V ++ + D+++E N + + K Sbjct: 163 NVCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAK 222 Query: 218 AGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVT 277 + + + + + L + + + R+ +GV+ V Sbjct: 223 SNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLHLRDSVR 282 Query: 278 F---APAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDP 331 VT S+ ++++ G+ V + ++ +V GD K P Sbjct: 283 VSEKEKIKVTEMYTSINGELCKIDRAYSGEIVIL-----QNEFLKLNSVLGDTKLLP 334 >5TY0-A nrPDB Length = 422 Score = 151 bits (382), Expect = 4e-37, Method: Composition-based stats. Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 28/174 (16%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K + N+ + HVD+GK+TTT ++Y G + E+ G+ W + Sbjct: 9 KLYRNIGIAAHVDAGKTTTTERVLYYTGM---------SHKIGEVHDGAATMDW----MV 55 Query: 65 AERERGITIDIALWKFET-------PKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 E+ERGITI A +++ +ID PGH DF+ + D A+++ Sbjct: 56 QEQERGITITSAATTCYWSGMDKQFESHRINIIDTPGHVDFMIEVERSLRVLDGAVVVFD 115 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 G + Q+ A GV + IV VNKMD + + R +K+ Sbjct: 116 SVAGV-------EPQSETVWRQANKYGVPR-IVFVNKMDRMGANFLRVVSQIKQ 161 >6N0I-A nrPDB Length = 706 Score = 151 bits (381), Expect = 6e-37, Method: Composition-based stats. Identities = 51/220 (23%), Positives = 86/220 (39%), Gaps = 38/220 (17%) Query: 1 MGKEKS---HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M + + N+ ++ HVD+GK+TTT +++ G + E+ G+ Sbjct: 4 MARTTPIELYRNIGIVAHVDAGKTTTTERILFYTG---------VNHKMGEVHDGAATMD 54 Query: 58 WVLDKLKAERERGITIDIALWKFET--------PKYQVTVIDAPGHRDFIKNMITGTSQA 109 W + E+ERGITI A KY+ +ID PGH DF + Sbjct: 55 W----MAQEQERGITITSAATTAFWQGSTKQFAHKYRFNIIDTPGHVDFTIEVERSLRVL 110 Query: 110 DCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIV 169 D A+++ +G G + Q+ A V +L +NKMD D R + + Sbjct: 111 DGAVVVFSGADGV-------EPQSETVWRQANKYHVPRL-AYINKMDRQGADFLRVVKQI 162 Query: 170 KETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWY 209 + ++G++P + S N I+ Y Sbjct: 163 DQ------RLGHHPVPIQLAIGSEENFMGQIDLVKMKAIY 196 Score = 42.2 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 60/187 (32%), Gaps = 15/187 (8%) Query: 169 VKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLE 228 ++E +++ + VP + S + + Y E A Sbjct: 249 IEEIKAGLRQRTIANEIVPTILGSSFKNKGVPLMLDAVIDYLPAPSEIPAIRGTDPD--- 305 Query: 229 AIDAIEQPSRPTD--KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTE 286 D + R D +P + +GT+ RV +GV+ G V + G Sbjct: 306 --DEEKHLERHADDKEPFSALAFKIATDPFVGTLTFARVYSGVLSSGNAVLNSVKGKKER 363 Query: 287 V-KSVEMH---HEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATV 342 + + V+MH +++ GD + +K++ G+ D F V Sbjct: 364 IGRMVQMHANQRAEIKDVCAGDIAAL----IGMKDVTTGDTLCDMDKPIILERMDFPDPV 419 Query: 343 IVLNHPG 349 I + Sbjct: 420 ISVAVEP 426 >4V6V-A1 nrPDB Length = 639 Score = 149 bits (375), Expect = 3e-36, Method: Composition-based stats. Identities = 53/180 (29%), Positives = 86/180 (47%), Gaps = 25/180 (13%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 IN+ ++ HVD+GK+T T L+Y G I E + +G+ + D + ER Sbjct: 4 INLGILAHVDAGKTTLTESLLYTSGAIA---------ELGSVDEGTTR----TDTMNLER 50 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +RGITI A+ F+ +V +ID PGH DF+ + S D A+L+++ G Sbjct: 51 QRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAKDGI----- 105 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESR-FQEIVKETSNFI---KKVGYNP 183 QTR + + I +NK+D D ++E+ + S+ I +KVG +P Sbjct: 106 --QAQTRILFHALQIMKIP-TIFFINKIDQEGIDLPMVYREMKAKLSSEIIVKQKVGQHP 162 >6B8D-A nrPDB Length = 408 Score = 148 bits (372), Expect = 6e-36, Method: Composition-based stats. Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 31/180 (17%) Query: 1 MGKEKS---HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M + + N+ + H+D+GK+TTT +++ G + E+ G+ Sbjct: 4 MARTTPIERYRNIGISAHIDAGKTTTTERILFYTG---------VSHKIGEVHDGAATMD 54 Query: 58 WVLDKLKAERERGITIDIALWKFET-------PKYQVTVIDAPGHRDFIKNMITGTSQAD 110 W ++ E+ERGITI A P++++ VID PGH DF + D Sbjct: 55 W----MEQEQERGITITSAATTAFWSGMSQQFPQHRINVIDTPGHVDFTVEVERSMRVLD 110 Query: 111 CAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK 170 A+++ G Q+ A V + I VNKMD + R E +K Sbjct: 111 GAVMVYCAVGGV-------QPQSETVWRQANKYEVPR-IAFVNKMDRTGANFLRVVEQLK 162 >4WQY-BZ nrPDB Length = 758 Score = 148 bits (372), Expect = 6e-36, Method: Composition-based stats. Identities = 51/231 (22%), Positives = 86/231 (37%), Gaps = 29/231 (12%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 K N+ + H+D+GK+TTT ++Y G I K E+ +G+ D ++ Sbjct: 77 KRLRNIGIAAHIDAGKTTTTERILYYTGRIHK---------IGEVHEGAATM----DFME 123 Query: 65 AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 ERERGITI A+ +++ +ID PGH DF + D AI++ G Sbjct: 124 QERERGITITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGV-- 181 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPK 184 + Q+ A V + I NKMD D +++G P Sbjct: 182 -----EPQSETVWRQAEKYKVPR-IAFANKMDKTGADLWLV------IRTMQERLGARPV 229 Query: 185 TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQ 235 + +I+ + G + + + E +D + Sbjct: 230 VMQLPIGREDTFSGIIDVLRMKAYTYG--NDLGTDIREIPIPEEYLDQARE 278 >6FEC-S nrPDB Length = 422 Score = 147 bits (371), Expect = 8e-36, Method: Composition-based stats. Identities = 77/355 (21%), Positives = 125/355 (35%), Gaps = 56/355 (15%) Query: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA-ELGKGSFKYAWVLDKL 63 ++ IN+ IGHV GKST + G R + E+ +LG + K + D Sbjct: 1 QATINIGTIGHVAHGKSTVVKAI---SGVHTVRFKNELERNITIKLGYANAKIYKLDDPS 57 Query: 64 KAERER----GITI------DIALWKFETPK-YQVTVIDAPGHRDFIKNMITGTSQADCA 112 E G + DI K V+ +D PGH + M+ G + D A Sbjct: 58 CPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAA 117 Query: 113 ILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKET 172 +L+IAG QT EH + ++ +++ NK+D VK +++ E ++ Sbjct: 118 LLLIAGNES------CPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAK--EQYEQI 169 Query: 173 SNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA 232 F++ G + P +PIS N+ + L Sbjct: 170 LAFVQ--GTVAEGAPIIPISAQLKYNI---EVVCEYIVKKIPVPPRDFTSEPRL------ 218 Query: 233 IEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT-------- 284 I S +KP G V G + GV+K G + P V+ Sbjct: 219 IVIRSFDVNKP------GCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLM 272 Query: 285 -----TEVKSVEMHHEQLEQGVPGDNVGFNVK---NVSVKEIRRGNVCGDAKNDP 331 +++ S+ H L+ PG +G K + + G V G P Sbjct: 273 CKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALP 327 >4FN5-A nrPDB Length = 709 Score = 147 bits (371), Expect = 8e-36, Method: Composition-based stats. Identities = 54/199 (27%), Positives = 81/199 (40%), Gaps = 37/199 (18%) Query: 1 MGKEKS---HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M + + N+ + HVD+GK+TTT +++ G + E+ G+ Sbjct: 4 MARTTPINRYRNIGICAHVDAGKTTTTERVLFYTG---------VNHKLGEVHDGAATTD 54 Query: 58 WVLDKLKAERERGITIDIALWKFETPK-------YQVTVIDAPGHRDFIKNMITGTSQAD 110 W + E+ERGITI A Y+V VID PGH DF + D Sbjct: 55 W----MVQEQERGITITSAAVTTFWKGSRGQYDNYRVNVIDTPGHVDFTIEVERSLRVLD 110 Query: 111 CAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK 170 A+++ G G + Q+ A GV + IV VNKMD + R E +K Sbjct: 111 GAVVVFCGTSGV-------EPQSETVWRQANKYGVPR-IVYVNKMDRQGANFLRVVEQIK 162 Query: 171 ETSNFIKKVGYNPKTVPFV 189 K++G+ P V Sbjct: 163 ------KRLGHTPVPVQLA 175 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 33/199 (16%), Positives = 61/199 (30%), Gaps = 15/199 (7%) Query: 157 SVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKET 216 + + E ++ + VP V S + + Y E Sbjct: 236 LMNKYLEEGELSEAEIKEGLRLRTLACEIVPAVCGSSFKNKGVPLVLDAVIDYLPAPTEI 295 Query: 217 KAGVVKGKTLLEAIDAIEQPSRPTD--KPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGM 274 A D + R D +P + +GT+ RV +GV+ G Sbjct: 296 PAIKGVSPD-----DETVEDERHADDNEPFSSLAFKIATDPFVGTLTFARVYSGVLSSGD 350 Query: 275 VVTFAPAGVTTEV-KSVEMH---HEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKND 330 V + G V + V+MH E++++ GD + +K++ G+ + Sbjct: 351 SVLNSVKGKKERVGRMVQMHANQREEIKEVRAGDIAAL----IGMKDVTTGDTLCSIEKP 406 Query: 331 PPKGCASFNATVIVLNHPG 349 F VI + Sbjct: 407 IILERMDFPEPVISVAVEP 425 >3TR5-A nrPDB Length = 528 Score = 147 bits (371), Expect = 8e-36, Method: Composition-based stats. Identities = 71/411 (17%), Positives = 131/411 (31%), Gaps = 98/411 (23%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +I H D+GK+T T L+ G I K K A D ++ E+ Sbjct: 14 RTFAIISHPDAGKTTLTEKLLLFGGAIQLAGTIKSRKAARHATS---------DWMELEK 64 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +RGI++ ++ +F Y + ++D PGH DF ++ + D A+++I G I Sbjct: 65 QRGISVTTSVMQFPYKDYLINLLDTPGHADFTEDTYRTLTAVDSALMVIDAAKGVEPRTI 124 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 + L ++ +NKMD D E++ E + + ++ P T P Sbjct: 125 K--------LMEVCRLRHTPIMTFINKMDR---DTRPSIELLDEIESIL-RIHCAPVTWP 172 Query: 188 FVPISGWNG-----DNMIEATTNAPWYKGWEKETKAGVVKGK------------------ 224 + G ++ I + E E G+ + Sbjct: 173 IGMGKYFKGIYHLIEDAIYLYQPGKHERVGESERIEGINNPELDKKLGDLASELRNEIEL 232 Query: 225 ---------------------------------TLLEA-IDAIEQPS-RPTDKPLRLPLQ 249 LL+A + P R T+ L P + Sbjct: 233 VKGASHPFEREGYLKGELTPIFFGSAINNFGVGELLDAFVKEAPPPQGRETNSRLVKPEE 292 Query: 250 DVYK-----------IGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMH----H 294 + + G + R+ +G + GM ++ + Sbjct: 293 EKFSGFVFKIQANMDPGHRDRIAFLRIASGQYQKGMKAYHVRLKKEIQINNALTFMAGKR 352 Query: 295 EQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVL 345 E E+ PGD +G + I+ G+ + G +F + + L Sbjct: 353 ENAEEAWPGDIIGLHNHGT----IQIGDTFTQGERFKFTGIPNFASELFRL 399 >6O81-S nrPDB Length = 472 Score = 146 bits (369), Expect = 1e-35, Method: Composition-based stats. Identities = 77/356 (21%), Positives = 125/356 (35%), Gaps = 56/356 (15%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA-ELGKGSFKYAWVLDK 62 ++ IN+ IGHV GKST + G R + E+ +LG + K + D Sbjct: 38 RQATINIGTIGHVAHGKSTVVKAI---SGVHTVRFKNELERNITIKLGYANAKIYKLDDP 94 Query: 63 LKAERER----GITI------DIALWKFETPK-YQVTVIDAPGHRDFIKNMITGTSQADC 111 E G + DI K V+ +D PGH + M+ G + D Sbjct: 95 SCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDA 154 Query: 112 AILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 A+L+IAG QT EH + ++ +++ NK+D VK +++ E ++ Sbjct: 155 ALLLIAGNES------CPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAK--EQYEQ 206 Query: 172 TSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAID 231 F++ G + P +PIS N+ + L Sbjct: 207 ILAFVQ--GTVAEGAPIIPISAQLKYNI---EVVCEYIVKKIPVPPRDFTSEPRL----- 256 Query: 232 AIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVT------- 284 I S +KP G V G + GV+K G + P V+ Sbjct: 257 -IVIRSFDVNKP------GCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKASEGKL 309 Query: 285 ------TEVKSVEMHHEQLEQGVPGDNVGFNVK---NVSVKEIRRGNVCGDAKNDP 331 +++ S+ H L+ PG +G K + + G V G P Sbjct: 310 MCKPKFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALP 365 >3ZZ0-A nrPDB Length = 693 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 24/166 (14%) Query: 1 MGKE---KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M +E + N+ +I H+D+GK+TTT ++Y G I K E +G+ + Sbjct: 1 MAREFSLEKTRNIGIIAHIDAGKTTTTERILYYTGRIHK---------IGETHEGASQMD 51 Query: 58 WVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA 117 W ++ E++RGITI A ++V +ID PGH DF + D A+ ++ Sbjct: 52 W----MEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLD 107 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDES 163 G + QT A T GV + IV VNKMD + + Sbjct: 108 AQSGV-------EPQTETVWRQATTYGVPR-IVFVNKMDKLGANFE 145 >5H7K-A nrPDB Length = 397 Score = 143 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 73/407 (17%), Positives = 141/407 (34%), Gaps = 94/407 (23%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M + + N+ + H+D GK+T + +L+ G I + K VL Sbjct: 18 MLQPERIRNIGIAAHIDHGKTTLSDNLLAGAGMISEELAGK---------------QLVL 62 Query: 61 DKLKAERERGITIDIA----LWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 D + E+ RGITI+ A + +E Y + +ID PGH DF ++ D I+++ Sbjct: 63 DFDEQEQARGITINAANVSMVHNYEGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIVV 122 Query: 117 AGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--------VKWDESRFQEI 168 G QT A V+ ++ +NK+D + RF +I Sbjct: 123 DAVEGVMP-------QTETVVRQALREYVKP-VLFINKVDRLIRELKLTPQQMMERFSKI 174 Query: 169 VKETSNFIKKVGY------------------------NPKTVPFVPISGWNGDNMIEATT 204 + + + I++ +VPF+ +G + +I+ T Sbjct: 175 IMDVNRLIQRYAPEEYKKKWMVKVEDGSVAFGSAYYNWALSVPFMKRTGVKFNEIIDLTL 234 Query: 205 NAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR----------------------PTDK 242 + ++ VV ++ + + + + Sbjct: 235 KGDN-RTLRQKAPLHVVVLDMVVRHLPSPIEAQKYRIPHLWEGDISSDIGQAMLNCDPKG 293 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVK--SVEMHHEQLE-Q 299 + + + + G V GRV +G +K G V ++ + M E++ + Sbjct: 294 KMVMVVTKIIIDKHAGEVATGRVWSGTVKSGQEVYLINTKRKARIQQVGIYMGPERINME 353 Query: 300 GVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLN 346 VP N+ V + ++ G + + +P F A VL Sbjct: 354 AVPAGNI-VAVTGL--RDAMAGETVAEEQIEP------FEALHYVLE 391 >4V7D-BZ nrPDB Length = 711 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 82/205 (40%), Gaps = 34/205 (16%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 + N+ + H+D+GK+TTT +++ G + E+ G+ W ++ E Sbjct: 9 YRNIGISAHIDAGKTTTTERILFYTG---------VNHKIGEVHDGAATMDW----MEQE 55 Query: 67 RERGITIDIALWKFETPK-------YQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGG 119 +ERGITI A +++ +ID PGH DF + D A+++ Sbjct: 56 QERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAV 115 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKV 179 G Q+ A V + I VNKMD + + F ++V + ++ Sbjct: 116 GGV-------QPQSETVWRQANKYKVPR-IAFVNKMDRMGAN---FLKVVNQIKT---RL 161 Query: 180 GYNPKTVPFVPISGWNGDNMIEATT 204 G NP + + + +++ Sbjct: 162 GANPVPLQLAIGAEEHFTGVVDLVK 186 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 29/183 (15%), Positives = 57/183 (31%), Gaps = 11/183 (6%) Query: 171 ETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAI 230 E +++ N + + S + + Y + A L + Sbjct: 246 EIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGI---LDDGK 302 Query: 231 DAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVT-FAPAGVTTEVKS 289 D + D+P + +G + RV +GV+ G V A + Sbjct: 303 DTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRI 362 Query: 290 VEMH---HEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLN 346 V+MH E++++ GD + +K++ G+ D F VI + Sbjct: 363 VQMHANKREEIKEVRAGD----IAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIA 418 Query: 347 HPG 349 Sbjct: 419 VEP 421 >5H7J-A nrPDB Length = 743 Score = 141 bits (356), Expect = 5e-34, Method: Composition-based stats. Identities = 66/367 (17%), Positives = 128/367 (34%), Gaps = 85/367 (23%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M + + N+ + H+D GK+T + +L+ G I + K VL Sbjct: 18 MLQPERIRNIGIAAHIDHGKTTLSDNLLAGAGMISEELAGK---------------QLVL 62 Query: 61 DKLKAERERGITIDIA----LWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 D + E+ RGITI+ A + +E Y + +ID PGH DF ++ D I+++ Sbjct: 63 DFDEQEQARGITINAANVSMVHNYEGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIVV 122 Query: 117 AGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--------VKWDESRFQEI 168 G QT A V+ ++ +NK+D + RF +I Sbjct: 123 DAVEGVMP-------QTETVVRQALREYVKP-VLFINKVDRLIRELKLTPQQMMERFSKI 174 Query: 169 VKETSNFIKKVGY------------------------NPKTVPFVPISGWNGDNMIEATT 204 + + + I++ +VPF+ +G + +I+ T Sbjct: 175 IMDVNRLIQRYAPEEYKKKWMVKVEDGSVAFGSAYYNWALSVPFMKRTGVKFNEIIDLTL 234 Query: 205 NAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR----------------------PTDK 242 + ++ VV ++ + + + + Sbjct: 235 KGD-NRTLRQKAPLHVVVLDMVVRHLPSPIEAQKYRIPHLWEGDISSDIGQAMLNCDPKG 293 Query: 243 PLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVK--SVEMHHEQLE-Q 299 + + + + G V GRV +G +K G V ++ + M E++ + Sbjct: 294 KMVMVVTKIIIDKHAGEVATGRVWSGTVKSGQEVYLINTKRKARIQQVGIYMGPERINME 353 Query: 300 GVPGDNV 306 VP N+ Sbjct: 354 AVPAGNI 360 >5TV2-A nrPDB Length = 405 Score = 140 bits (353), Expect = 9e-34, Method: Composition-based stats. Identities = 68/351 (19%), Positives = 125/351 (35%), Gaps = 42/351 (11%) Query: 1 MGKEKS---HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYA 57 M ++ + N+ + HVD+GK+TTT +++ G + E+ G+ Sbjct: 1 MARKTPIERYRNIGICAHVDAGKTTTTERILFYTG---------LSHKIGEVHDGAATMD 51 Query: 58 WVLDKLKAERERGITIDIAL-------WKFETPKYQVTVIDAPGHRDFIKNMITGTSQAD 110 W ++ E+ERGITI A + + ++V +ID PGH DF + D Sbjct: 52 W----MEQEQERGITITSAATTTFWRGMEAQFQDHRVNIIDTPGHVDFTIEVERSLRVLD 107 Query: 111 CAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK 170 A+++ G G + Q+ A V + +V VNKMD D R + +K Sbjct: 108 GAVVVFCGSSGV-------EPQSETVWRQADKYHVPR-MVFVNKMDRAGADFLRVVDQIK 159 Query: 171 ETSNFIKKVGYNPKTVPFVPISGWNGDNMIE--ATTNAPWYKGWEKETKAGVVKGKTLLE 228 ++G NP + + + +I+ W + + T ++E Sbjct: 160 ------NRLGANPVPIQLNVGAEEDFKGVIDLIKMKMINWNEADQGMTFTYEEIPADMIE 213 Query: 229 AIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVK 288 + L D Y G T + + A G + K Sbjct: 214 LAEEWRNNLVEAAAEASEELMDKYLEEGELTEAEIKQALRARTLNNEIVLATCGSAFKNK 273 Query: 289 SVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFN 339 V+ + + + +P +K + + V A ++ P +F Sbjct: 274 GVQAVLDAVIEYLPSPIDVPAIKGIDENDNE---VERHADDNEPFSALAFK 321 >3J81-k nrPDB Length = 527 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 84/364 (23%), Positives = 127/364 (34%), Gaps = 72/364 (19%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA-ELGKGSFKYAWVLDK 62 ++ IN+ IGHV GKST + G R ++ E+ +LG + K + Sbjct: 97 RQATINIGTIGHVAHGKSTVVRAI---SGVQTVRFKDELERNITIKLGYANAKIYKCQEP 153 Query: 63 LKAERE--RGITIDIALW-KFETPK--------YQVTVIDAPGHRDFIKNMITGTSQADC 111 E + R D + K + P V+ +D PGH + M++G + D Sbjct: 154 TCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDA 213 Query: 112 AILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 A+L+IAG QT EH + ++ +I+ NK+D ++ E E K Sbjct: 214 ALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR--EESALEHQKS 265 Query: 172 TSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAID 231 FI+ G P VPIS N+ + Sbjct: 266 ILKFIR--GTIADGAPIVPISAQLKYNIDAVNE-----------------------FIVK 300 Query: 232 AIEQPSRPTDKPLRLPL---QDVYKIGG-----IGTVPVGRVETGVIKPGMVVTFAPAGV 283 I P R RL + DV K G G V G + GV K G + P V Sbjct: 301 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV 360 Query: 284 T-------------TEVKSVEMHHEQLEQGVPGDNVGFNVK---NVSVKEIRRGNVCGDA 327 T + + S+ L+ VPG +G K + + G V G Sbjct: 361 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK 420 Query: 328 KNDP 331 + P Sbjct: 421 GHLP 424 >3VQT-A nrPDB Length = 548 Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats. Identities = 45/188 (23%), Positives = 76/188 (40%), Gaps = 21/188 (11%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 +I H D+GK+T T L+ G I K K A D + ERE Sbjct: 33 TFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKARKAARHATS---------DWMAMERE 83 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 RGI++ ++ +F V ++D PGH+DF ++ + D A+++I G Sbjct: 84 RGISVTTSVMQFPYRDRVVNLLDTPGHQDFSEDTYRVLTAVDSALVVIDAAKGV------ 137 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 + QTR+ + + ++ VNKMD +++ ++ P T P Sbjct: 138 -EAQTRK-LMDVCRMRATPVMTFVNKMDREALHPLDVMADIEQHL----QIECAPMTWPI 191 Query: 189 VPISGWNG 196 S + G Sbjct: 192 GMGSSFKG 199 >4V89-AW nrPDB Length = 534 Score = 136 bits (342), Expect = 2e-32, Method: Composition-based stats. Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 21/181 (11%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +I H D+GK+T T ++ I K G+GS ++A D ++ E+ Sbjct: 14 RTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVK--------GRGSNQHAKS-DWMEMEK 64 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +RGI+I ++ +F V ++D PGH DF ++ + DC +++I G + Sbjct: 65 QRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTR 124 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 TR L ++ +NK+D D E++ E N +K +G P T P Sbjct: 125 KLMEVTR--------LRDTPILTFMNKLDRDIRDP---MELLDEVENELK-IGCAPITWP 172 Query: 188 F 188 Sbjct: 173 I 173 >6GB2-BC nrPDB Length = 657 Score = 132 bits (332), Expect = 3e-31, Method: Composition-based stats. Identities = 57/302 (18%), Positives = 105/302 (34%), Gaps = 67/302 (22%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++GHVD GK+T K + A E G Sbjct: 113 VTIMGHVDHGKTTLLDK------------FRKTQVAAVETG------------------- 141 Query: 70 GITIDIALWKFETP-KYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 GIT I + P ++T +D PGH F G D +L++A G + + Sbjct: 142 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 200 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 ++ +HA A +I+AVNK D + D + ++ + + G V Sbjct: 201 ---ESIQHAKDAQV----PIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 250 Query: 189 VPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPL 248 VP+S GDN++ A+ + + + P+ + Sbjct: 251 VPVSALTGDNLMALAEATV---------------------ALAEMLELKADPNGPVEGTV 289 Query: 249 QDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSV-EMHHEQLEQGVPGDNVG 307 + + G G V ++ G ++ G +V+ + + + + +++ P VG Sbjct: 290 IESFTDKGRGLVTTAIIQRGTLRKGS--VLVAGKCWAKVRLMFDENGKTIDEAYPSMPVG 347 Query: 308 FN 309 Sbjct: 348 IT 349 >3IZY-P nrPDB Length = 537 Score = 121 bits (304), Expect = 5e-28, Method: Composition-based stats. Identities = 57/300 (19%), Positives = 104/300 (34%), Gaps = 65/300 (21%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++GHVD GK+T L K + A E G Sbjct: 7 VTIMGHVDHGKTTLLDKL------------RKTQVAAMEAG------------------- 35 Query: 70 GITIDIALWKFETP-KYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 GIT I + P ++T +D PGH F GT D IL++A G + + Sbjct: 36 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGTQVTDIVILVVAADDGVMKQTV- 94 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 ++ +HA A +++A+NK D + D + ++ + + G V Sbjct: 95 ---ESIQHAKDAHV----PIVLAINKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 144 Query: 189 VPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPL 248 V +S G+NM+ L E ++ P+ + + Sbjct: 145 VHVSALTGENMMALAE-----------------ATIALAEMLELKADPTGAVEG----TV 183 Query: 249 QDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGF 308 + + G G V ++ G ++ G ++ + + + + + + P VG Sbjct: 184 IESFTDKGRGPVTTAIIQRGTLRKGSILVAGKSWAKVRLM-FDENGRAVNEAYPSMPVGI 242 >4V6W-Az nrPDB Length = 844 Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats. Identities = 56/227 (24%), Positives = 78/227 (34%), Gaps = 54/227 (23%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M K+++ N+ VI HVD GKST T L+ K G I A+ G+ F Sbjct: 13 MDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGII----------AGAKAGETRFT----- 57 Query: 61 DKLKAERERGITIDIAL--WKFETP------------------KYQVTVIDAPGHRDFIK 100 D K E+ER ITI FE + + +ID+PGH DF Sbjct: 58 DTRKDEQERCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSS 117 Query: 101 NMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS--- 157 + D A++++ G QT A ++ I+ +NKMD Sbjct: 118 EVTAALRVTDGALVVVDCVSGVC-------VQTETVLRQAIAERIKP-ILFMNKMDRALL 169 Query: 158 --------VKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNG 196 + R E V G V P G G Sbjct: 170 ELQLDAEELYQTFQRIVENVNVIIATYNDDGGPMGEVRVDPSKGSVG 216 Score = 36.0 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 28/190 (14%), Positives = 56/190 (29%), Gaps = 28/190 (14%) Query: 239 PTDKPLRLPLQDVYKIGGIGTV-PVGRVETGVIKPGMVVTFAPAG----------VTTEV 287 D PL + + + G GRV G + G Sbjct: 375 DPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQ 434 Query: 288 KSVEMHHEQLE--QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVL 345 +++ M +E + VP N+ + V ++ G K+ F+ + +V Sbjct: 435 RTILMMGRYVEAIEDVPSGNI-CGLVGVDQFLVKTG-TITTFKDAHNMKVMKFSVSPVVR 492 Query: 346 NHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPS 405 + P L + L K+D +E+ + + +G Sbjct: 493 VAVEPKNPADLPKL--------VEGLKRLAKSDPMVQCIIEESGEHIIAGAG-----ELH 539 Query: 406 KPMCVEAFSE 415 +C++ E Sbjct: 540 LEICLKDLEE 549 >3J4J-A nrPDB Length = 569 Score = 118 bits (296), Expect = 5e-27, Method: Composition-based stats. Identities = 55/220 (25%), Positives = 84/220 (38%), Gaps = 42/220 (19%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV++GHVD GK+T +L R EKEA Sbjct: 76 VVIMGHVDHGKTTLLDYL---------RKSRIAEKEAG---------------------- 104 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT + ++ +TP+ V ID PGH F G AD A+++IA G Sbjct: 105 GITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGIMP----- 159 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QT E A G + LI A+NK+D + D + + + E ++ G + +P Sbjct: 160 --QTEEAIAHAKAAGAK-LIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPIS 216 Query: 190 PISGWNGDNMIE---ATTNAPWYKGWEKETKAGVVKGKTL 226 +G +++E Y+ GV+ L Sbjct: 217 AKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILESKL 256 >4KJZ-A nrPDB Length = 473 Score = 118 bits (296), Expect = 5e-27, Method: Composition-based stats. Identities = 55/220 (25%), Positives = 84/220 (38%), Gaps = 42/220 (19%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV++GHVD GK+T +L R EKEA Sbjct: 75 VVIMGHVDHGKTTLLDYL---------RKSRIAEKEAG---------------------- 103 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT + ++ +TP+ V ID PGH F G AD A+++IA G Sbjct: 104 GITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGIMP----- 158 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QT E A G + LI A+NK+D + D + + + E ++ G + +P Sbjct: 159 --QTEEAIAHAKAAGAK-LIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPIS 215 Query: 190 PISGWNGDNMIE---ATTNAPWYKGWEKETKAGVVKGKTL 226 +G +++E Y+ GV+ L Sbjct: 216 AKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILESKL 255 >4B44-A nrPDB Length = 363 Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 55/220 (25%), Positives = 84/220 (38%), Gaps = 42/220 (19%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV++GHVD GK+T +L R EKEA Sbjct: 76 VVIMGHVDHGKTTLLDYL---------RKSRIAEKEAG---------------------- 104 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT + ++ +TP+ V ID PGH F G AD A+++IA G Sbjct: 105 GITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGIMP----- 159 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QT E A G + LI A+NK+D + D + + + E ++ G + +P Sbjct: 160 --QTEEAIAHAKAAGAK-LIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPIS 216 Query: 190 PISGWNGDNMIE---ATTNAPWYKGWEKETKAGVVKGKTL 226 +G +++E Y+ GV+ L Sbjct: 217 AKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILESKL 256 >2P8Y-T nrPDB Length = 842 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 47/187 (25%), Positives = 73/187 (39%), Gaps = 39/187 (20%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M K + N+ VI HVD GKST T L+ + G I AA+ G+ F Sbjct: 13 MDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIIS----------AAKAGEARFT----- 57 Query: 61 DKLKAERERGITIDIALWKFETP----------------KYQVTVIDAPGHRDFIKNMIT 104 D K E+ERGITI + + + +ID+PGH DF + Sbjct: 58 DTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTA 117 Query: 105 GTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESR 164 D A++++ G QT A ++ +V +NK+D + Sbjct: 118 ALRVTDGALVVVDTIEGVC-------VQTETVLRQALGERIKP-VVVINKVDRALLELQV 169 Query: 165 FQEIVKE 171 +E + + Sbjct: 170 SKEDLYQ 176 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 26/220 (11%), Positives = 61/220 (27%), Gaps = 31/220 (14%) Query: 139 LAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDN 198 ++ V + K++ V + + E ++K + + + Sbjct: 287 AIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPV 346 Query: 199 MIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIG 258 +A Y+G + + I + L L + + G Sbjct: 347 TAQAYRAEQLYEGPADDA--------------NCIAIKNCDPKADLMLYVSKMVPTSDKG 392 Query: 259 TV-PVGRVETGVIKPGMVVTFAPAG-------------VTTEVKSVEMHHEQLEQGVPGD 304 GRV G +K G V + V + E ++ G+ Sbjct: 393 RFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGN 452 Query: 305 NVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIV 344 +G + + ++ G ++ F+ + +V Sbjct: 453 IIG--LVGIDQFLLKTG-TLTTSETAHNMKVMKFSVSPVV 489 >2LKD-A nrPDB Length = 178 Score = 114 bits (286), Expect = 6e-26, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 71/201 (35%), Gaps = 41/201 (20%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M + + + +GHVD GK+T + Sbjct: 4 MVERPPVVTI--MGHVDHGKTTLLDAI-------------------------------RH 30 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 K+ + GIT I ++ ++T +D PGH F G D IL++A Sbjct: 31 SKVTEQEAGGITQHIGAYQVTVNDKKITFLDTPGHEAFTTMRARGAQVTDIVILVVAADD 90 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 G QT E A V +IVA+NKMD + + R + + E + ++ G Sbjct: 91 GVMP-------QTVEAINHAKAANVP-IIVAINKMDKPEANPDRVMQELMEYNLVPEEWG 142 Query: 181 YNPKTVPFVPISGWNGDNMIE 201 + + D+++E Sbjct: 143 GDTIFCKLSAKTKEGLDHLLE 163 >1ZO1-I nrPDB Length = 501 Score = 106 bits (263), Expect = 3e-23, Method: Composition-based stats. Identities = 53/268 (19%), Positives = 89/268 (33%), Gaps = 63/268 (23%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++GHVD GK++ ++ + + E G Sbjct: 7 VTIMGHVDHGKTSLLEYI------------RSTKVASGEAG------------------- 35 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT I + ET +T +D PGH F G D +L++A G Sbjct: 36 GITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMP----- 90 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 QT E A+ ++VAVNK+D + D R + + + ++ G + V Sbjct: 91 --QTIE-AIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVS 147 Query: 190 PISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQ 249 +G D +++A + + G+ G + +D Sbjct: 148 AKAGTGIDELLDAILLQAEVLELKA-VRKGMASGAVIESFLD------------------ 188 Query: 250 DVYKIGGIGTVPVGRVETGVIKPGMVVT 277 G G V V G + G +V Sbjct: 189 -----KGRGPVATVLVREGTLHKGDIVL 211 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 34/80 (42%), Gaps = 5/80 (6%) Query: 248 LQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGV---TTEVKSVEMHHEQLEQGVPGD 304 ++DV+K G + V GV+K + V E++S+ + + + G Sbjct: 413 VRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGM 472 Query: 305 NVGFNVKNVSVKEIRRGNVC 324 G VKN ++R G+V Sbjct: 473 ECGIGVKNY--NDVRTGDVI 490 >3JCN-b nrPDB Length = 890 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 51/268 (19%), Positives = 87/268 (32%), Gaps = 63/268 (23%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++GHVD GK++ ++ + + E G Sbjct: 394 VTIMGHVDHGKTSLLDYI------------RSTKVASGEAG------------------- 422 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 GIT I + ET +T +D PGH F G D +L++A G I Sbjct: 423 GITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTI-- 480 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 + +HA A V + NK+D + D R + + + ++ G + V Sbjct: 481 --EAIQHAKAAQVPVVVAV----NKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVS 534 Query: 190 PISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQ 249 +G D +++A + + G+ G + +D Sbjct: 535 AKAGTGIDELLDAILLQAEVLELKA-VRKGMASGAVIESFLD------------------ 575 Query: 250 DVYKIGGIGTVPVGRVETGVIKPGMVVT 277 G G V V G + G +V Sbjct: 576 -----KGRGPVATVLVREGTLHKGDIVL 598 Score = 33.3 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 34/80 (42%), Gaps = 5/80 (6%) Query: 248 LQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGV---TTEVKSVEMHHEQLEQGVPGD 304 ++DV+K G + V GV+K + V E++S+ + + + G Sbjct: 800 VRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGM 859 Query: 305 NVGFNVKNVSVKEIRRGNVC 324 G VKN ++R G+V Sbjct: 860 ECGIGVKNY--NDVRTGDVI 877 >1WDT-A nrPDB Length = 665 Score = 102 bits (254), Expect = 3e-22, Method: Composition-based stats. Identities = 70/387 (18%), Positives = 127/387 (32%), Gaps = 88/387 (22%) Query: 1 MGKEKSHI--NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAW 58 MG E + V ++GH SGK+T T L+YK G ++R E G + Sbjct: 1 MGTEGGAMIRTVALVGHAGSGKTTLTEALLYKTGAKERRGRV-------EEGTTTT---- 49 Query: 59 VLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAG 118 D + T+ + ++V ++DAPG+ DF+ + AD A++ ++ Sbjct: 50 --DYTPEAKLHRTTVRTGVAPLLFRGHRVFLLDAPGYGDFVGEIRGALEAADAALVAVSA 107 Query: 119 GVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIK- 177 G T +A LG+ +++V V K+D + +++ + Sbjct: 108 EAGVQVG-------TERAWTVAERLGLPRMVV-VTKLDKGGDYYALLEDLRSTLGPILPI 159 Query: 178 -----KVGYNPKTVPFVPISGWNGDNMIEATTNAP------WYKGWEKETKAGVVKGKTL 226 + G + + +N E P + ++ +A V + L Sbjct: 160 DLPLYEGGKWVGLIDVFHGKAYRYENGEEREAEVPPEERERVQRFRQEVLEAIVETDEGL 219 Query: 227 LE----------------------------------------------AIDAIEQP-SRP 239 LE ++A+ P R Sbjct: 220 LEKYLEGEEVTGEALEKAFHEAVRRGLLYPVALASGEREIGVLPLLELILEALPSPTERF 279 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHE--QL 297 D P + V +G V R+ G +KPG + V V M + ++ Sbjct: 280 GDGPPLAKVFKVQVDPFMGQVAYLRLYRGRLKPGDSLQSEAGQVRLPHLYVPMGKDLLEV 339 Query: 298 EQGVPGDNVGFNVKNVSVKEIRRGNVC 324 E+ G +G + + RG V Sbjct: 340 EEAEAGFVLGV----PKAEGLHRGMVL 362 >6MTD-v nrPDB Length = 839 Score = 101 bits (251), Expect = 6e-22, Method: Composition-based stats. Identities = 44/208 (21%), Positives = 72/208 (34%), Gaps = 37/208 (17%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M K+ + N+ VI HVD GKST T L+ K G I + K + ++ Sbjct: 12 MDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIARCITIKSTAISLFYELSENDLNFIK 71 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 + + + +ID+PGH DF + D A++++ Sbjct: 72 QSK-----------------DGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVS 114 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDE--------SRFQEIVKET 172 G QT A ++ ++ +NKMD + FQ IV+ Sbjct: 115 GVC-------VQTETVLRQAIAERIKP-VLMMNKMDRALLELQLEPEELYQTFQRIVENV 166 Query: 173 SNFIKKVG----YNPKTVPFVPISGWNG 196 + I G + P+ G G Sbjct: 167 NVIISTYGEGESGPMGNIMIDPVLGTVG 194 Score = 36.4 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 33/101 (32%), Gaps = 16/101 (15%) Query: 239 PTDKPLRLPLQDVYKIGGIGTV-PVGRVETGVIKPGMVVTFAPAG-------------VT 284 PL + + + G GRV +G++ G+ V + Sbjct: 370 DPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQ 429 Query: 285 TEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCG 325 + + + E +E G+ VG + V ++ G + Sbjct: 430 RTILMMGRYVEPIEDVPCGNIVG--LVGVDQFLVKTGTITT 468 >5FG3-A nrPDB Length = 623 Score = 88.0 bits (216), Expect = 7e-18, Method: Composition-based stats. Identities = 60/295 (20%), Positives = 104/295 (35%), Gaps = 33/295 (11%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VVV+GHVD GK+T + + A S A V++K+ ++ Sbjct: 19 VVVLGHVDHGKTTLLDKIRRTAVAAKEAGGITQHIGA------SIVPADVIEKIAEPLKK 72 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 I + + + + ID PGH F G S AD AIL++ G Sbjct: 73 VIPVKLVIPG-------LLFIDTPGHELFSNLRRRGGSVADFAILVVDIMEGF------- 118 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDS-VKWDE-------SRFQEIVKETSNFIKKVGY 181 QT E L V LI A NK+D W + + +++ Y Sbjct: 119 KPQTYEALELLKERRVPFLIAA-NKIDRIPGWKPNPDAPFIETIRRQDPKVREILEQRVY 177 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA--IEQPSRP 239 + I+ T G+ + +L + +++ R Sbjct: 178 EIVGKMYEAGLPAELFTRIKDFRRKIAIVPVSARTGEGIPELLAVLAGLTQTYLKERLRY 237 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAG--VTTEVKSVEM 292 + P + + +V ++ G GTV + GV+K ++ + T V+++ M Sbjct: 238 AEGPAKGVVLEVKEMQGFGTVVDAVIYDGVLKKEDIIVVGGREGPIVTRVRALLM 292 Score = 31.7 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 42/109 (38%), Gaps = 6/109 (5%) Query: 204 TNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVG 263 + + + E K L+A++++ +P + R+ V++ + Sbjct: 444 ESMIYKLIEDYEEWVKKEKEAERLKALNSLIRPGK-----FRILPGYVFRRSDP-AIVGV 497 Query: 264 RVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKN 312 V GVI+PG V + + +++ LE+ G V +++ Sbjct: 498 EVLGGVIRPGYPVMDSQGRELGRIMAIKDRDRSLEEARLGAAVAVSIQG 546 >5YT0-A nrPDB Length = 364 Score = 86.8 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 60/295 (20%), Positives = 104/295 (35%), Gaps = 33/295 (11%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VVV+GHVD GK+T + + A S A V++K+ ++ Sbjct: 19 VVVLGHVDHGKTTLLDKIRRTAVAAKEAGGITQHIGA------SIVPADVIEKIAEPLKK 72 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 I + + + + ID PGH F G S AD AIL++ G Sbjct: 73 VIPVKLVIPG-------LLFIDTPGHELFSNLRRRGGSVADFAILVVDIMEGF------- 118 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDS-VKWDE-------SRFQEIVKETSNFIKKVGY 181 QT E L V LI A NK+D W + + +++ Y Sbjct: 119 KPQTYEALELLKERRVPFLIAA-NKIDRIPGWKPNPDAPFIETIRRQDPKVREILEQRVY 177 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDA--IEQPSRP 239 + I+ T G+ + +L + +++ R Sbjct: 178 EIVGKMYEAGLPAELFTRIKDFRRKIAIVPVSARTGEGIPELLAVLAGLTQTYLKERLRY 237 Query: 240 TDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAG--VTTEVKSVEM 292 + P + + +V ++ G GTV + GV+K ++ + T V+++ M Sbjct: 238 AEGPAKGVVLEVKEMQGFGTVVDAVIYDGVLKKEDIIVVGGREGPIVTRVRALLM 292 >1G7S-A nrPDB Length = 594 Score = 86.4 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 63/388 (16%), Positives = 123/388 (31%), Gaps = 87/388 (22%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V V+GHVD GK+T H+ R +EA + + +D ++ Sbjct: 8 VSVLGHVDHGKTTLLDHI---------RGSAVASREAGGITQHIGATEIPMDVIE----- 53 Query: 70 GITID-IALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 GI D + + + ID PGH F G + AD AILI+ G Sbjct: 54 GICGDFLKKFSIRETLPGLFFIDTPGHEAFTTLRKRGGALADLAILIVDINEGF------ 107 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVK-------------------WDESRFQEIV 169 QT+E + +VA NK+D + + + V Sbjct: 108 -KPQTQEALNILRMYRTP-FVVAANKIDRIHGWRVHEGRPFMETFSKQDIQVQQKLDTKV 165 Query: 170 KETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAG 219 E + + G+ + V +PIS G+ + E T + Sbjct: 166 YELVGKLHEEGFESERFDRVTDFASQVSIIPISAITGEGIPELLTMLMGLAQQYLREQLK 225 Query: 220 VVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA 279 + + D P R + +V + G+G + G+++ + Sbjct: 226 IEE------------------DSPARGTILEVKEETGLGMTIDAVIYDGILRKDDTIAMM 267 Query: 280 PAG--VTTEVKSVEMHH------------EQLEQGVPGDNVGFNVKNVSVKEIRRGNVCG 325 + ++T ++S+ +++++ V + + ++ G+ Sbjct: 268 TSKDVISTRIRSLLKPRPLEEMRESRKKFQKVDEVVAAAGIKIVAPGID--DVMAGSPL- 324 Query: 326 DAKNDPPKGCASFNATVIVLNHPGQISA 353 DP K + + + + Sbjct: 325 RVVTDPEKVREEILSEIEDIKIDTDEAG 352 >6ID0-C nrPDB Length = 972 Score = 86.4 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 43/206 (20%), Positives = 72/206 (34%), Gaps = 36/206 (17%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M + NV + GH+ GK+ LI E+ E+ K + Sbjct: 123 MDNSELIRNVTLCGHLHHGKTCFVDCLI--------------EQTHPEIRKRYDQDLCYT 168 Query: 61 DKLKAERERGITIDIALWKFETPK-----YQVTVIDAPGHRDFIKNMITGTSQADCAILI 115 D L E+ERG+ I P Y ++D PGH +F + G +D +L Sbjct: 169 DILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLF 228 Query: 116 IAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDES--------RFQE 167 I G + +HA+ + V +NK+D + + + + Sbjct: 229 IDAAEGVMLNT----ERLIKHAVQERLA----VTVCINKIDRLILELKLPPTDAYYKLRH 280 Query: 168 IVKETSNFIKKVGYNPKTVPFVPISG 193 IV E + I + + P+ G Sbjct: 281 IVDEVNGLISMYS-TDENLILSPLLG 305 >3JB9-B nrPDB Length = 984 Score = 85.7 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 34/192 (17%), Positives = 72/192 (37%), Gaps = 35/192 (18%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 + + +V GH+ GKS L+Y K + + Sbjct: 135 LTGTDDVRSFIVAGHLHHGKSALLDLLVYYTHPDTKPPKRRSLRY--------------T 180 Query: 61 DKLKAERERGITI-----DIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILI 115 D ERER ++I +A+ + + ID PGH DF+ + + +D +L+ Sbjct: 181 DTHYLERERVMSIKSTPLTLAVSDMKGKTFAFQCIDTPGHVDFVDEVAAPMAISDGVVLV 240 Query: 116 IAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDE--------SRFQE 167 + G + +HA+L +++ +NK+D + + + + Sbjct: 241 VDVIEGVMINT----TRIIKHAILHD----MPIVLVLNKVDRLILELRLPPNDAYHKLRH 292 Query: 168 IVKETSNFIKKV 179 ++ E ++ I ++ Sbjct: 293 VIDEVNDNICQI 304 Score = 31.7 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 22/56 (39%), Gaps = 1/56 (1%) Query: 232 AIEQPSRPTDKPLRLPLQDVYK-IGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTE 286 AI + SR PL + + +Y + RV +G +K G V + E Sbjct: 476 AILEMSREESAPLVMHVTKLYNTVDANNFYAFARVYSGQVKKGQKVKVLGENYSLE 531 >4UJC-AB nrPDB Length = 627 Score = 81.4 bits (199), Expect = 8e-16, Method: Composition-based stats. Identities = 63/331 (19%), Positives = 110/331 (33%), Gaps = 49/331 (14%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 + V+GHVD+GK+ L + E G + + L+A E+ Sbjct: 41 ICVLGHVDTGKTKILDKL------------RHTHVQDGEAGGITQQIGATNVPLEAINEQ 88 Query: 70 GITIDIALWKFETPKYQVT---VIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 I F+ ++ +ID PGH F G+S D AIL++ G Sbjct: 89 TKMIK----NFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHG----- 139 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSV-----KWDESRFQEIVKETSNFIKKVGY 181 + QT E L + IVA+NK+D + D + K+ N + Sbjct: 140 --LEPQTIESINLLKSKKCP-FIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEE 196 Query: 182 NPKTVPF-VPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGK---TLLEAIDAIEQPS 237 K + G N E + G G L+E + Sbjct: 197 RAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKR 256 Query: 238 RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAG--VTTEVKS------ 289 + LR + +V + G+GT + G +K G + + T+++ Sbjct: 257 LAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQIRGLLLPPP 316 Query: 290 -----VEMHHEQLEQGVPGDNVGFNVKNVSV 315 V+ +E+ ++ V K++ Sbjct: 317 MKELRVKNQYEKHKEVEAAQGVKILGKDLEK 347 >4NCL-A nrPDB Length = 457 Score = 79.1 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 51/351 (14%), Positives = 114/351 (32%), Gaps = 91/351 (25%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHVD+GK+ + + + E G + + ++A +++ Sbjct: 13 CCILGHVDTGKTKLLDKI------------RQTNVQEGEAGGITQQIGATYFPVEAIKQK 60 Query: 70 GITIDI-ALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 ++ ++F+ P + +ID PGH F G+S + AIL++ G Sbjct: 61 TAVVNKDGKFEFKVPG--LLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHG------- 111 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQEIV 169 + QT E L +VA+NK+D + K ++ F+ + Sbjct: 112 LEPQTIESLRLLRE-RKTPFVVALNKIDRLYGWKKIENNGFRESFALQNKAVQNEFRNRL 170 Query: 170 KETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAG 219 + + G+N + V VP S G+ + + + ++ + Sbjct: 171 DQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDMLK--LIVQLCQERMASS 228 Query: 220 VVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA 279 ++ L + ++ I G G + G+++ G + Sbjct: 229 LMYLSELQATVLEVKA------------------IEGFGVTIDVILSNGILREGDRIVLC 270 Query: 280 PAG----------------VTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVS 314 +K +HH++++ V + + Sbjct: 271 GLEGPIKTNIRALLTPAPMRELRIKGQYIHHKEVK---AAQGVKISAPGLE 318 >4N3G-A nrPDB Length = 603 Score = 77.6 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 51/351 (14%), Positives = 114/351 (32%), Gaps = 91/351 (25%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHVD+GK+ + + + E G + + ++A +++ Sbjct: 13 CCILGHVDTGKTKLLDKI------------RQTNVQEGEAGGITQQIGATYFPVEAIKQK 60 Query: 70 GITIDI-ALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 ++ ++F+ P + +ID PGH F G+S + AIL++ G Sbjct: 61 TAVVNKDGKFEFKVPG--LLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHG------- 111 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQEIV 169 + QT E L +VA+NK+D + K ++ F+ + Sbjct: 112 LEPQTIESLRLLRE-RKTPFVVALNKIDRLYGWKKIENNGFRESFALQNKAVQNEFRNRL 170 Query: 170 KETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAG 219 + + G+N + V VP S G+ + + + ++ + Sbjct: 171 DQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDMLK--LIVQLCQERMASS 228 Query: 220 VVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA 279 ++ L + ++ I G G + G+++ G + Sbjct: 229 LMYLSELQATVLEVKA------------------IEGFGVTIDVILSNGILREGDRIVLC 270 Query: 280 PAG----------------VTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVS 314 +K +HH++++ V + + Sbjct: 271 GLEGPIKTNIRALLTPAPMRELRIKGQYIHHKEVK---AAQGVKISAPGLE 318 >4TN1-B nrPDB Length = 345 Score = 74.1 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 50/351 (14%), Positives = 113/351 (32%), Gaps = 91/351 (25%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHV +GK+ + + + E G + + ++A +++ Sbjct: 13 CCILGHVRTGKTKLLDKI------------RQTNVQEGEAGGITQQIGATYFPVEAIKQK 60 Query: 70 GITIDI-ALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 ++ ++F+ P + +ID PGH F G+S + AIL++ G Sbjct: 61 TAVVNKDGKFEFKVPG--LLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHG------- 111 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQEIV 169 + QT E L +VA+NK+D + K ++ F+ + Sbjct: 112 LEPQTIESLRLLRE-RKTPFVVALNKIDRLYGWKKIENNGFRESFALQNKAVQNEFRNRL 170 Query: 170 KETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAG 219 + + G+N + V VP S G+ + + + ++ + Sbjct: 171 DQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDMLK--LIVQLCQERMASS 228 Query: 220 VVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFA 279 ++ L + ++ I G G + G+++ G + Sbjct: 229 LMYLSELQATVLEVKA------------------IEGFGVTIDVILSNGILREGDRIVLC 270 Query: 280 PAG----------------VTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVS 314 +K +HH++++ V + + Sbjct: 271 GLEGPIKTNIRALLTPAPMRELRIKGQYIHHKEVK---AAQGVKISAPGLE 318 >4V8Y-CP nrPDB Length = 339 Score = 72.2 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 57/337 (16%), Positives = 106/337 (31%), Gaps = 86/337 (25%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHVD+GK+ + + + A + K + + E++ Sbjct: 8 CCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPIDAIKAKTKV-MAEYEKQ- 65 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 F+ P V ID PGH F G+S + AIL+I G Sbjct: 66 ---------TFDVPGLLV--IDTPGHESFSNLRSRGSSLCNIAILVIDIMHG-------L 107 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQEIVK 170 + QT E L +VA+NK+D + + + FQ Sbjct: 108 EQQTIESIKLLRDRKAP-FVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRYS 166 Query: 171 ETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGV 220 + + + G N + V VP S G+ + + + T+ + Sbjct: 167 KIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLL------WLLLELTQKRM 220 Query: 221 VKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAP 280 K L ++A + +V + G GT + G ++ G + Sbjct: 221 SKQLMYLSHVEAT--------------ILEVKVVEGFGTTIDVILSNGYLREGDRIVLCG 266 Query: 281 AG----------------VTTEVKSVEMHHEQLEQGV 301 +KS +HH++++ + Sbjct: 267 MNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAAL 303 >4NCF-A nrPDB Length = 457 Score = 72.2 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 57/337 (16%), Positives = 106/337 (31%), Gaps = 86/337 (25%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHVD+GK+ + + + A + K + + E++ Sbjct: 13 CCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPIDAIKAKTKV-MAEYEKQ- 70 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 F+ P V ID PGH F G+S + AIL+I G Sbjct: 71 ---------TFDVPGLLV--IDTPGHESFSNLRSRGSSLCNIAILVIDIMHG-------L 112 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQEIVK 170 + QT E L +VA+NK+D + + + FQ Sbjct: 113 EQQTIESIKLLRDRKAP-FVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRYS 171 Query: 171 ETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGV 220 + + + G N + V VP S G+ + + + T+ + Sbjct: 172 KIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLL------WLLLELTQKRM 225 Query: 221 VKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAP 280 K L ++A + +V + G GT + G ++ G + Sbjct: 226 SKQLMYLSHVEAT--------------ILEVKVVEGFGTTIDVILSNGYLREGDRIVLCG 271 Query: 281 AG----------------VTTEVKSVEMHHEQLEQGV 301 +KS +HH++++ + Sbjct: 272 MNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAAL 308 >3WBI-A nrPDB Length = 606 Score = 71.0 bits (172), Expect = 9e-13, Method: Composition-based stats. Identities = 60/340 (17%), Positives = 111/340 (32%), Gaps = 92/340 (27%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHVD+GK+ + R EA + + + +D +KA+ Sbjct: 12 CCILGHVDTGKTKLLDKI---------RQTNVQGGEAGGITQQIGATYFPIDAIKAK--- 59 Query: 70 GITIDIALWKFETPKYQVT---VIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 + ++E + V VID PGH F G+S + AIL+I G Sbjct: 60 ----TKVMAEYEKQTFDVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHG----- 110 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQE 167 + QT E L +VA+NK+D + + + FQ Sbjct: 111 --LEQQTIESIKLLRDRKAP-FVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQS 167 Query: 168 IVKETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETK 217 + + + G N + V VP S G+ + + + T+ Sbjct: 168 RYSKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLL------WLLLELTQ 221 Query: 218 AGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVT 277 + K L ++A + +V + G GT + G ++ G + Sbjct: 222 KRMSKQLMYLSHVEAT--------------ILEVKVVEGFGTTIDVILSNGYLREGDRIV 267 Query: 278 FAPAG----------------VTTEVKSVEMHHEQLEQGV 301 +KS +HH++++ + Sbjct: 268 LCGMNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAAL 307 >4V8Z-CV nrPDB Length = 586 Score = 69.5 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 60/340 (17%), Positives = 111/340 (32%), Gaps = 92/340 (27%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 ++GHVD+GK+ + R EA + + + +D +KA+ Sbjct: 8 CCILGHVDTGKTKLLDKI---------RQTNVQGGEAGGITQQIGATYFPIDAIKAK--- 55 Query: 70 GITIDIALWKFETPKYQVT---VIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 + ++E + V VID PGH F G+S + AIL+I G Sbjct: 56 ----TKVMAEYEKQTFDVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHG----- 106 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSV-------------------KWDESRFQE 167 + QT E L +VA+NK+D + + + FQ Sbjct: 107 --LEQQTIESIKLLRDRKAP-FVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQS 163 Query: 168 IVKETSNFIKKVGYNPK----------TVPFVPISGWNGDNMIEATTNAPWYKGWEKETK 217 + + + G N + V VP S G+ + + + T+ Sbjct: 164 RYSKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLL------WLLLELTQ 217 Query: 218 AGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVT 277 + K L ++A + +V + G GT + G ++ G + Sbjct: 218 KRMSKQLMYLSHVEAT--------------ILEVKVVEGFGTTIDVILSNGYLREGDRIV 263 Query: 278 FAPAG----------------VTTEVKSVEMHHEQLEQGV 301 +KS +HH++++ + Sbjct: 264 LCGMNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAAL 303 >2QTH-A nrPDB Length = 364 Score = 55.2 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 29/205 (14%), Positives = 70/205 (34%), Gaps = 46/205 (22%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK 62 K + ++ ++G+ +SGK++ L +D + Sbjct: 175 KRNNIPSIGIVGYTNSGKTSLFNSLTGLTQKVDTKLF----------------------- 211 Query: 63 LKAERERGITIDIALWKFETPKYQVTVIDAPGH--------RDFIKNMITGTSQADCAIL 114 T+ + ++ ++D G D ++ +D IL Sbjct: 212 --------TTMSPKRYAIPINNRKIMLVDTVGFIRGIPPQIVDAFFVTLSEAKYSDALIL 263 Query: 115 IIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSN 174 +I E + + Q+ L + + ++V +NK+D + D + ++V++ S Sbjct: 264 VIDSTFS--ENLLIETLQSSFEILREIGVSGKPILVTLNKIDKINGDLYKKLDLVEKLSK 321 Query: 175 FIKKVGYNPKTVPFVPISGWNGDNM 199 + ++ +PIS N+ Sbjct: 322 ELYSPIFD-----VIPISALKRTNL 341 >4DCU-A nrPDB Length = 456 Score = 49.1 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 57/181 (31%), Gaps = 23/181 (12%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIK--------NMITGTSQADCA---ILIIAG 118 G T D F + + ++D G R K +++ D + +++ G Sbjct: 228 GTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDG 287 Query: 119 GVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKK 178 G E G E +++ VNK D+V DES +E + + + Sbjct: 288 EEGIIEQDKRIAGYAHEAGKA--------VVIVVNKWDAVDKDESTMKEFEENIRDHFQF 339 Query: 179 VGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 + Y P + +S + V +++A+ P+ Sbjct: 340 LDY----APILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTH 395 Query: 239 P 239 Sbjct: 396 N 396 Score = 36.0 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 16/103 (15%) Query: 66 ERERGITIDIALWKFETPKYQVTVIDAP----GHRDFIKNMIT----GTSQADCAILIIA 117 E G+T D E Y +ID G F+ + +AD I ++ Sbjct: 52 EDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMDEADVIIFMVN 111 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKW 160 G G A E A + + + +++AVNK+D+ + Sbjct: 112 GREGVTAAD-------EEVAKILYRTK-KPVVLAVNKLDNTEM 146 >3IEU-A nrPDB Length = 301 Score = 48.3 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 60/192 (31%), Gaps = 42/192 (21%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK--LKAER 67 + ++G + GKST L+ + I R + + A +D L E Sbjct: 11 IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEE 70 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +R I + K + + I ++ G + Sbjct: 71 KRAI------------NRLMN-----------KAASSSIGDVELVIFVVEGTRWTPDD-- 105 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 E L G +I+AVNK+D+V + + ++ + + Sbjct: 106 -------EMVLNKLREGKAPVILAVNKVDNV--------QEKADLLPHLQFLASQMNFLD 150 Query: 188 FVPISGWNGDNM 199 VPIS G N+ Sbjct: 151 IVPISAETGLNV 162 >3J8G-X nrPDB Length = 490 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 37/233 (15%), Positives = 73/233 (31%), Gaps = 36/233 (15%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 I + ++G + GKST T ++ + + + + ++D R Sbjct: 203 IKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGV-R 261 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 +RG I A+ KF + + A+ +L+I G + + Sbjct: 262 KRG-KITDAVEKFS-----------------VIKTLQAIEDANVVMLVIDAREGISDQDL 303 Query: 128 SKDGQTREHALLAFTLGVRQ-LIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 S LL F L + L++ VNK D + QE+ ++ + Sbjct: 304 S---------LLGFILNSGRSLVIVVNKWDGLS------QEVKEQVKETLDFRLGFIDFA 348 Query: 187 PFVPISGWNGDNMIEATTNA-PWYKGWEKETKAGVVKGKTLLEAIDAIEQPSR 238 IS +G + + Y + ++ + D R Sbjct: 349 RVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVR 401 >2WIC-A nrPDB Length = 267 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 45/257 (17%), Positives = 81/257 (31%), Gaps = 46/257 (17%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 + V +IG+ +SGK+T L + ER Sbjct: 4 LTVGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTV-----------------------ER 40 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILI--IAGGVGEFEA 125 + GI F T +QVT++D PG + I+ + D I I G + Sbjct: 41 KEGI--------FATTDHQVTLVDLPG--TYSLTTISSQTSLDEQIACHYILSGDADMLI 90 Query: 126 GISKDGQTREHALLAFTLGVR--QLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNP 183 + + L L +VA+N +D + + R + ++G Sbjct: 91 NVVDASNLERNLYLTLQLLELGIPCVVALNMLDIAEKQQVRI-----DIDALAARLGCP- 144 Query: 184 KTVPFVPISGWNGDNMIEATTNAPWYKGWE--KETKAGVVKGKTLLEAIDAIEQPSRPTD 241 +P V G + + A E + + + L + + A P + Sbjct: 145 -VIPLVSTRGRGIEALKIALDRHQANSDLELVHYPQPLLREADLLAQQMSAQIPPRQRRW 203 Query: 242 KPLRLPLQDVYKIGGIG 258 L++ D+Y G Sbjct: 204 LGLQMLEGDIYSRAYAG 220 >5DN8-A nrPDB Length = 446 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 45/240 (18%), Positives = 73/240 (30%), Gaps = 55/240 (22%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 I + +IG + GKST L+ + I V D+ Sbjct: 179 IKIAMIGRPNVGKSTLINRLLGEERVI------------------------VYDQP---- 210 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHR------DFIK--NMITGTSQA---DCAILII 116 G T D F T+ID G R D+++ +MI D I ++ Sbjct: 211 --GTTRDSIYIPFARNDENYTLIDTAGIRRRAKIQDYVEKFSMIKSLQAMHAADVVIFLL 268 Query: 117 AGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFI 176 G E + + E + LI+AVNK D + +E N I Sbjct: 269 DARQGVTEQDLRLLNRIVEAGV--------SLIIAVNKWDGLNIEER------DNVRNAI 314 Query: 177 KKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQP 236 + IS +G + + ++ + L +A+ E P Sbjct: 315 DRRMPFVDFARRYFISALHGTGVGKLFRAIQESYQSIQQELTTGQLTRALEKAVAEHEPP 374 >2E87-A nrPDB Length = 357 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 43/197 (21%), Positives = 62/197 (31%), Gaps = 48/197 (24%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 VV+ GH + GKST L I Sbjct: 169 TVVIAGHPNVGKSTLLKALTTAKPEIASYPFTT--------------------------- 201 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDF-IKNMITGTSQADCAI-----LIIAGGVGE 122 RGI + +FE ++ +ID PG D I QA A+ LII Sbjct: 202 RGINV----GQFEDGYFRYQIIDTPGLLDRPISERNEIEKQAILALRYLGNLIIYIFDPS 257 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 G + Q + +V +NK+D +E +K F+K+ G N Sbjct: 258 EHCGFPLEEQIHLFEEVHGEFKDLPFLVVINKIDVAD------EENIKRLEKFVKEKGLN 311 Query: 183 PKTVPFVPISGWNGDNM 199 P + IS G + Sbjct: 312 P-----IKISALKGTGI 323 >4R98-A nrPDB Length = 271 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 83/243 (34%), Gaps = 51/243 (20%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 + + +IG+ +SGK+T L G W Sbjct: 4 LTIGLIGNPNSGKTTLFNQLT---------------------GSRQRVGNWA-------- 34 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQAD-----CAILIIAGGVGE 122 G+T++ +F T +QVT++D PG + I+ + D IL + Sbjct: 35 --GVTVERKEGQFSTTDHQVTLVDLPG--TYSLTTISSQTSLDEQIACHYILSGDADLLI 90 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 S + L LG+ IVA+N +D + R E ++G Sbjct: 91 NVVDASNLERNLYLTLQLLELGIP-CIVALNMLDIAEKQNIRI-----EIDALSARLGC- 143 Query: 183 PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDK 242 P +P+ + N+ + + E V + LL D++ + P+D Sbjct: 144 ----PVIPLVATDTKNV-QFVLKLAIDRYKANENVELVHYAQPLLNEADSLAKVM-PSDI 197 Query: 243 PLR 245 PL+ Sbjct: 198 PLK 200 >3R9W-A nrPDB Length = 307 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 61/202 (30%), Gaps = 33/202 (16%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++G + GKST +L+ K + + G + V + + Sbjct: 12 VAIVGKPNVGKSTLLNNLL----------GTKVSIISPKAGTTRMRVLGVKNIPNEAQI- 60 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 I +D D GH ++ +AD + +I G Sbjct: 61 -IFLDTPGIYEPKKS------DVLGH-SMVEIAKQSLEEADVILFMIDATEGWRPRD--- 109 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 E + +IV +NK+D + ++ E +P+ V Sbjct: 110 ----EEIYQNFIKPLNKPVIVVINKIDKIGP-AKNVLPLIDEIHKK------HPELTEIV 158 Query: 190 PISGWNGDNMIEATTNAPWYKG 211 PIS G N+ E Y Sbjct: 159 PISALKGANLDELVKTILKYLP 180 >5FV0-A nrPDB Length = 517 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 47/289 (16%), Positives = 93/289 (32%), Gaps = 20/289 (6%) Query: 9 NVVVIGHVDSGKSTTTGH-LIYKCGGIDKRTIEKFEKEAAELGKGSFK-YAWVLDKLKAE 66 N+ + G GKSTT L+ G + + + + + D + + Sbjct: 34 NIGIFGSAGYGKSTTMMTLLLSFAGAYNPAQLHYYIFDFGNSALLPLRQLPHTADYFRLD 93 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGG--VGEFE 124 E+ I I K E + + ++ + S+ I+I+A E Sbjct: 94 DEKKIEKFIKFMKEEMEQRKQRFMEK---EVSTIKLYNALSEEKLPIIIVALDNFDVVKE 150 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMD-----SVKWDESRFQEIVKETSNFIKKV 179 + Q ++A +LG+ ++ A ++ + +++ ++S + Sbjct: 151 EMPDFETQLIQYARDGQSLGIFFIMTA-TRVSGIRPPLMNNLKTKIVHYFIDSSEKFSLI 209 Query: 180 GYNPKTVPFVPISGW-NGDNMIEATTNAPWYKGWEKETKAGVV-KGKTLLEAIDAIEQPS 237 G P V +P DN P + E V + + L E I +P Sbjct: 210 GRTPYDVDPIPGRALIKKDNAALTQIYLPADGEDDIEVLENVKREMERLKEVYQHIPKPK 269 Query: 238 RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTE 286 P RL + V+ + G + G+ T P + Sbjct: 270 PIPMLPPRLSM-SVFTNTYVQHRASGFIPVGL----DEQTVRPVAINMR 313 >5KH0-A nrPDB Length = 396 Score = 41.8 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 36/194 (18%) Query: 70 GITIDIALWKFE-TPKYQVTVIDAPGHRDF-------IKNMITGTSQADCAILIIAGGVG 121 G T D E +P +T+ID PG D IK +ADC ILI+ G Sbjct: 41 GTTTDPVFKSMELSPVGPITLIDTPGLDDVGELGIKRIKKAKKSLYRADCGILIVDDIPG 100 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGY 181 FE I L L + I A+NK+D++ D ++ K+ Sbjct: 101 NFEEQI---------IKLFKELEIPYFI-AINKIDTI--DHENIEKEYKKY--------- 139 Query: 182 NPKTVPFVPISGWN--GDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRP 239 VP + +S G I T N+ K E + ++ G L+ I + Sbjct: 140 ---NVPILKVSALKKIGFEKIGKTINSILPKDDEIPYLSDLIDGGDLV--ILVVPIDLGA 194 Query: 240 TDKPLRLPLQDVYK 253 L +P + Sbjct: 195 PKGRLIMPQVHAIR 208 >1MKY-A nrPDB Length = 439 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 69/231 (29%), Gaps = 29/231 (12%) Query: 2 GKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLD 61 + I V ++G + GKST ++ K + + + +D Sbjct: 175 PEITDAIKVAIVGRPNVGKSTLFNAILNKERALVSPIPGTTRDPVDDEVFIDGRKYVFVD 234 Query: 62 KLKAERERGITIDIALWKFETPKY-QVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 R+ + KY V+D +AD ++++ Sbjct: 235 TAGLRRK------SRVEPRTVEKYSNYRVVD-------------SIEKADVVVIVLDATQ 275 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 G G + +V NK D V E R+ E K + + Sbjct: 276 GITRQDQRMAGLMERRGRAS--------VVVFNKWDLVVHREKRYDEFTKLFREKLYFID 327 Query: 181 YNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAID 231 Y+P GWN D MI+A A + + A + +L + Sbjct: 328 YSPLIFT-SADKGWNIDRMIDAMNLAYASYTTKVPSSAINSALQKVLAFTN 377 Score = 39.1 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 54/279 (19%), Positives = 88/279 (31%), Gaps = 73/279 (26%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 V+++G + GKST L+ K I E E Sbjct: 3 TVLIVGRPNVGKSTLFNKLVKKKKAI------------------------------VEDE 32 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITG---------TSQADCAILIIAGG 119 G+T D E ++D G D +++I+ +AD + ++ G Sbjct: 33 EGVTRDPVQDTVEWYGKTFKLVDTCGVFDNPQDIISQKMKEVTLNMIREADLVLFVVDGK 92 Query: 120 VGEFEAGISKDGQTREHALLAFTLGVRQL--IVAVNKMDSVKWDESRFQEIVKETSNFIK 177 G T+E LA L + I+ NK +E +E + Sbjct: 93 RGI----------TKEDESLADFLRKSTVDTILVANKA-------ENLREFEREVKPELY 135 Query: 178 KVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLL---------- 227 +G+ + +P N D M+E KG + E+K + + Sbjct: 136 SLGF-GEPIPVSAEHNINLDTMLETIIKKLEEKGLDLESKPEITDAIKVAIVGRPNVGKS 194 Query: 228 EAIDAIEQPSRPTDKPL----RLPLQDVYKIGGIGTVPV 262 +AI R P+ R P+ D I G V V Sbjct: 195 TLFNAILNKERALVSPIPGTTRDPVDDEVFIDGRKYVFV 233 >4V0N-A nrPDB Length = 169 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 59/192 (30%), Gaps = 41/192 (21%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +NV+V+G +SGK+T L + ++AAE+ Sbjct: 7 VNVLVVGLDNSGKTTIIERL------------KPRPRQAAEVAPTV-------------- 40 Query: 68 ERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGI 127 G T+D + E TV D G + +AD + ++ Sbjct: 41 --GFTVD----EVEKGPLTFTVFDMSGAGRYRTLWEQYYREADAVVFVVDSADKLRMVVA 94 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 + EH L + ++ NK D E + + + Sbjct: 95 RDEM---EHMLKHSNMRKVPILYFANKKDLPVAMPPV------EIAQALGLDDIKDRPWQ 145 Query: 188 FVPISGWNGDNM 199 VP +G G+ + Sbjct: 146 IVPSNGLTGEGV 157 >2CXX-A nrPDB Length = 190 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 62/172 (36%), Gaps = 29/172 (16%) Query: 47 AELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGH----------- 95 + +GK + Y K++ + G+T I + E ++ +ID PG Sbjct: 10 SNVGKSTLIYRLTGKKVRRGKRPGVTRKI--IEIEWKNHK--IIDMPGFGFMMGLPKEVQ 65 Query: 96 ----RDFIKNMITGTSQADCAILIIAGGVGEFEAGISKD----GQTREHALLAFTLGVRQ 147 + + + D A+L++ G + E L + Sbjct: 66 ERIKDEIVHFIEDNAKNIDVAVLVVDGKAAPEIIKRWEKRGEIPIDVEFYQFLRELDIP- 124 Query: 148 LIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNM 199 IVAVNK+D + QE++ + + V F+PIS GDN+ Sbjct: 125 TIVAVNKLDKI----KNVQEVINFLAEKFEVPLSEIDKV-FIPISAKFGDNI 171 >5WDR-A nrPDB Length = 171 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 38/126 (30%), Gaps = 12/126 (9%) Query: 77 LWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREH 136 + + ++D G D+ + + + + + + RE Sbjct: 47 HVSIDDEACLLDILDTAGQEDYSAMRDQYMRTGEGFLCVYSIDSQ---QSLDEIHSFREQ 103 Query: 137 ALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNG 196 L +I+ NK D E +E S + ++PF+ S Sbjct: 104 ILRVKDQDEVPMILVGNKCDL---------EEHREVSTEAGQAVAKSYSIPFMETSAKKR 154 Query: 197 DNMIEA 202 N+ EA Sbjct: 155 INVEEA 160 >4ARZ-A nrPDB Length = 310 Score = 37.1 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 59/175 (33%), Gaps = 12/175 (6%) Query: 67 RERGITIDIALWKFET-PKYQVTVIDAPGHRDFIKNMITG-----TSQADCAILIIAGGV 120 R G TID+ + + D G F++N T I + Sbjct: 36 RRLGATIDVEHSHLRFLGNMTLNLWDCGGQDVFMENYFTKQKDHIFQMVQVLIHVFDVES 95 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWD--ESRFQEIVKETSNFIKK 178 E I + + ++ V ++KMD V+ D E FQ ++K S + Sbjct: 96 TEVLKDIEIFAKALKQLR--KYSPDAKIFVLLHKMDLVQLDKREELFQIMMKNLSETSSE 153 Query: 179 VGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAI 233 G+ + P S W+ + ++ + K K ++ A++ I Sbjct: 154 FGFP--NLIGFPTSIWDESLYKAWSQIVCSLIPNMSNHQSNLKKFKEIMNALEII 206 >2QU8-A nrPDB Length = 228 Score = 36.8 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 45/127 (35%), Gaps = 16/127 (12%) Query: 71 ITIDIALWKFETPKYQVTVIDAPGHRD--------FIKNMITGTSQADCAILIIAGGVGE 122 T ++ + F+ + +ID PG D IT + + IL I Sbjct: 62 TTKNLYVGHFDHKLNKYQIIDTPGLLDRAFENRNTIEMTTITALAHINGVILFI--IDIS 119 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWD------ESRFQEIVKETSNFI 176 + G++ Q + + +++ NK+D D + ++I+ N I Sbjct: 120 EQCGLTIKEQINLFYSIKSVFSNKSIVIGFNKIDKCNMDSLSIDNKLLIKQILDNVKNPI 179 Query: 177 KKVGYNP 183 K ++ Sbjct: 180 KFSSFST 186 >1WF3-A nrPDB Length = 301 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 30/229 (13%), Positives = 70/229 (30%), Gaps = 49/229 (21%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++G + GKST +L+ + K R R Sbjct: 10 VAIVGKPNVGKSTLLNNLLGVKVAPISPRPQTTRK----------------------RLR 47 Query: 70 GITIDIALWKFETPKYQVTVIDAPG-HR------DFI-KNMITGTSQADCAILIIAGGVG 121 GI + Q+ +D PG H+ +F+ + + + + + ++ Sbjct: 48 GI--------LTEGRRQIVFVDTPGLHKPMDALGEFMDQEVYEALADVNAVVWVVDLRHP 99 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGY 181 L +G +++ NK+D+ K+ E + + ++ Sbjct: 100 PTPEDELV------ARALKPLVGKVPILLVGNKLDAAKYPEEAMKAYHELLPEAEPRMLS 153 Query: 182 NPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAI 230 + +++ P++ E K+ G+ + E + Sbjct: 154 ALDERQVAELKA----DLLALMPEGPFFYP-EDYAKSDQTFGEWVAEIL 197 >1YR7-A nrPDB Length = 262 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 33/195 (16%), Positives = 59/195 (30%), Gaps = 20/195 (10%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 VV +G SGK+T TG K + EL ++ Sbjct: 17 VVFVGTAGSGKTTLTGEFGRYLEDNYKVAYVNLDTGVKELPYEPSIDVREFVTVEEIMRE 76 Query: 70 GITIDIALWKFE-----------------TPKYQVTVIDAPGHRDFIKNMITGTSQADC- 111 G + A+ + + +ID PG + G + Sbjct: 77 GYGPNGAIVESYDRLMEKFNEYLNKILRLEKENDYVLIDTPGQMETFLFHEFGVRLMENL 136 Query: 112 -AILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDE-SRFQEIV 169 L++ E + R ALL I A+NK+D + +E R ++ Sbjct: 137 PYPLVVYISDPEILKKPNDYCFVRFFALLIDLRLGATTIPALNKVDLLSEEEKERHRKYF 196 Query: 170 KETSNFIKKVGYNPK 184 ++ ++ +P Sbjct: 197 EDIDYLTARLKLDPS 211 >5X4B-A nrPDB Length = 162 Score = 36.0 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 16/103 (15%) Query: 66 ERERGITIDIALWKFETPKYQVTVIDAP----GHRDFIKNMIT----GTSQADCAILIIA 117 E G+T D E Y +ID G F+ + +AD I ++ Sbjct: 31 EDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMDEADVIIFMVN 90 Query: 118 GGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKW 160 G G A E A + + + +++AVNK+D+ + Sbjct: 91 GREGVTAAD-------EEVAKILYRTK-KPVVLAVNKLDNTEM 125 >3GEH-A nrPDB Length = 462 Score = 35.6 bits (80), Expect = 0.042, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 54/158 (34%), Gaps = 19/158 (12%) Query: 28 IYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL-DKLKAERERGITIDIALWKFETPKYQ 86 G + + ++ +GK S AW D+ G T D+ + Sbjct: 214 TKDKGELLRTGLKVAIVGRPNVGKSSLLNAWSQSDRAIVTDLPGTTRDVVESQLVVGGIP 273 Query: 87 VTVIDAPGHRDFIKNMIT--------GTSQADCAILIIAGGVGEFEAGISKDGQTREHAL 138 V V+D G R+ + + AD +L I G + G + + +H Sbjct: 274 VQVLDTAGIRETSDQVEKIGVERSRQAANTADLVLLTIDAATG-WTTGDQEIYEQVKH-- 330 Query: 139 LAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFI 176 R LI+ +NK+D V+ E + + + Sbjct: 331 -------RPLILVMNKIDLVEKQLITSLEYPENITQIV 361 >3PIR-A nrPDB Length = 183 Score = 35.6 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 13/129 (10%), Positives = 41/129 (31%), Gaps = 12/129 (9%) Query: 75 IALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTR 134 + + + + V+D G +F D +++ + + + Q Sbjct: 56 LKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLI 115 Query: 135 EHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGW 194 + +I+ NK+D + + + + + + +P++ S Sbjct: 116 LRVKDRESF---PMILVANKVDLMHLRKVTRDQGKEMATKY---------NIPYIETSAK 163 Query: 195 NGDNMIEAT 203 + ++ T Sbjct: 164 DPPLNVDKT 172 >1UDX-A nrPDB Length = 416 Score = 35.6 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 28/197 (14%), Positives = 63/197 (31%), Gaps = 51/197 (25%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 V ++G+ ++GKS+ + I V++ + ER Sbjct: 160 VGLVGYPNAGKSSLLAAMTRAHPKIAPYPFTTLSPNLG-----------VVEVSEEER-- 206 Query: 70 GITIDIALWKFETPKYQVTVIDAPG-------HRDFIKNMITGTSQADCAILIIAGGVGE 122 T+ D PG + + ++ + ++ Sbjct: 207 -----------------FTLADIPGIIEGASEGKGLGLEFLRHIARTRVLLYVLDAADEP 249 Query: 123 FEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYN 182 + + +E L R +VA+NK+D ++ +E VK ++ + + G Sbjct: 250 LKT---LETLRKEVGAYDPALLRRPSLVALNKVDLLE------EEAVKALADALAREG-- 298 Query: 183 PKTVPFVPISGWNGDNM 199 + +P+S G + Sbjct: 299 ---LAVLPVSALTGAGL 312 >3K53-A nrPDB Length = 271 Score = 34.8 bits (78), Expect = 0.074, Method: Composition-based stats. Identities = 42/241 (17%), Positives = 80/241 (33%), Gaps = 43/241 (17%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 V ++G+ + GK+T L + EK+ + ++ V Sbjct: 5 TVALVGNPNVGKTTIFNALTGLRQHVGNWPGVTVEKKEGIMEYREKEFLVVDLP------ 58 Query: 69 RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 GI A E ++D G+ D I +++ T L Sbjct: 59 -GIYSLTAHSIDELIARNF-ILD--GNADVIVDIVDSTCLMRNLFL-------------- 100 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 T E F + V+ +I+ +NK D +K ++ + K++G VP Sbjct: 101 ----TLE----LFEMEVKNIILVLNKFDLLKKKGAKI-----DIKKMRKELG-----VPV 142 Query: 189 VPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLE-AIDAIEQPSRPTDKPLRLP 247 +P + G+ + E + T + + +E I I + R T + P Sbjct: 143 IPTNAKKGEGVEELKRMIALMAEGKVTTNPIIPRYDEDIEREIKHISELLRGTPLAEKYP 202 Query: 248 L 248 + Sbjct: 203 I 203 >1XZP-A nrPDB Length = 482 Score = 34.8 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 37/249 (14%), Positives = 80/249 (32%), Gaps = 54/249 (21%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 + +V++G + GKST L+ + I +E Sbjct: 244 LRMVIVGKPNVGKSTLLNRLLNEDRAIVTDIPGTTRDVISEEIVI--------------- 288 Query: 68 ERGI---TIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFE 124 RGI +D A + ET +++ G ++ + D + ++ E Sbjct: 289 -RGILFRIVDTAGVRSETND----LVERLGIERTLQEIEKA----DIVLFVLDASSPLDE 339 Query: 125 AGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPK 184 E + + ++ +V +NK+D V+ +E N + Sbjct: 340 ----------EDRKILERIKNKRYLVVINKVDVVEKINE------EEIKNKL------GT 377 Query: 185 TVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEA--IDAIEQPSRPTDK 242 V IS G+ + E + + + E + L + ++ ++ K Sbjct: 378 DRHMVKISALKGEGL-EKLEESIYRETQEIFERGSDSLITNLRQKQLLENVKGHLEDAIK 436 Query: 243 PLR--LPLQ 249 L+ +P+ Sbjct: 437 SLKEGMPVD 445 >3JAJ-z nrPDB Length = 426 Score = 34.8 bits (78), Expect = 0.089, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 61/172 (35%), Gaps = 36/172 (20%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYK------------CGGIDKRTIEKFEKEAAELG 50 K K ++ ++ +G SGK+TT L Y ++ ++ A + Sbjct: 95 KGKQNV-IMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKAR 153 Query: 51 KGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPG-HRD---FIKNMITGT 106 + +D + I + KF+ +++ ++D G H+ + M+ Sbjct: 154 IPFYGSYTEMDPV-------IIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVA 206 Query: 107 S--QADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMD 156 + Q D + ++ +G Q E AF V V V K+D Sbjct: 207 NAIQPDNIVYVMDASIG----------QACEAQAKAFKDKVDVASVIVTKLD 248 >6FRK-x nrPDB Length = 504 Score = 34.4 bits (77), Expect = 0.090, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 61/172 (35%), Gaps = 36/172 (20%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYK------------CGGIDKRTIEKFEKEAAELG 50 K K ++ ++ +G SGK+TT L Y ++ ++ A + Sbjct: 98 KGKQNV-IMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKAR 156 Query: 51 KGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPG-HRD---FIKNMITGT 106 + +D + I + KF+ +++ ++D G H+ + M+ Sbjct: 157 IPFYGSYTEMDPV-------IIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVA 209 Query: 107 S--QADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMD 156 + Q D + ++ +G Q E AF V V V K+D Sbjct: 210 NAIQPDNIVYVMDASIG----------QACEAQAKAFKDKVDVASVIVTKLD 251 >5L3Q-A nrPDB Length = 442 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 61/172 (35%), Gaps = 36/172 (20%) Query: 3 KEKSHINVVVIGHVDSGKSTTTGHLIYK------------CGGIDKRTIEKFEKEAAELG 50 K K ++ ++ +G SGK+TT L Y ++ ++ A + Sbjct: 104 KGKQNV-IMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKAR 162 Query: 51 KGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPG-HRD---FIKNMITGT 106 + +D + I + KF+ +++ ++D G H+ + M+ Sbjct: 163 IPFYGSYTEMDPV-------IIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVA 215 Query: 107 S--QADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMD 156 + Q D + ++ +G Q E AF V V V K+D Sbjct: 216 NAIQPDNIVYVMDASIG----------QACEAQAKAFKDKVDVASVIVTKLD 257 >5J40-A nrPDB Length = 372 Score = 34.1 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 52/157 (33%), Gaps = 36/157 (22%) Query: 14 GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITI 73 G +DSGK+T L+ CGG E+ ELG G ++ V + +K Sbjct: 171 GPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKG-------- 222 Query: 74 DIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQT 133 + P GH G S DC + G + + + Q Sbjct: 223 -TGAESRDLPS---------GH---------GISNLDC---LRDYLDGSVKVNLERKHQN 260 Query: 134 REHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVK 170 + + IV +N+ + ++RF + Sbjct: 261 KRTQV------FPPGIVTMNEYSVPRTLQARFVRQID 291 >5VAI-A nrPDB Length = 380 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 43/140 (30%), Gaps = 7/140 (5%) Query: 55 KYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAIL 114 + +V R R +T I KF+ K + D G RD + I + I Sbjct: 173 QDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIF 232 Query: 115 IIAGGVGEFEAGISKDGQTREHALLAFT-------LGVRQLIVAVNKMDSVKWDESRFQE 167 ++A + AL F L +I+ +NK D + + Sbjct: 233 VVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKS 292 Query: 168 IVKETSNFIKKVGYNPKTVP 187 +++ + P Sbjct: 293 KIEDYFPEFARYTTPEDATP 312 >5LAD-A nrPDB Length = 404 Score = 34.1 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 49/146 (33%), Gaps = 27/146 (18%) Query: 70 GITIDIALWKFE-TPKYQVTVIDAPGHRDF-------IKNMITGTSQADCAILIIAGGVG 121 G T D E P VT++D PG D ++ +ADC IL+ Sbjct: 42 GTTTDPVYKSMELYPVGPVTLVDTPGLDDVGELGRLRVEKARRVFYRADCGILVTDSEPT 101 Query: 122 EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE-------TSN 174 +E + + E +V VNK+D + + + + + Sbjct: 102 PYEDDVVNLFKEMEI----------PFVVVVNKIDVLGEKAEELKGLYESRYEAKVLLVS 151 Query: 175 FIKKVGYNPKTVPFVPISGWNGDNMI 200 ++K G++ I GD I Sbjct: 152 ALQKKGFDDIGKTISEI--LPGDEEI 175 >2WJG-A nrPDB Length = 188 Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 41/225 (18%), Positives = 68/225 (30%), Gaps = 51/225 (22%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 + +IG+ + GKST L G+ + W Sbjct: 10 IALIGNPNVGKSTIFNALT---------------------GENVYIGNWP---------- 38 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 G+T++ +FE + V+D PG N I D I Sbjct: 39 GVTVEKKEGEFEYNGEKFKVVDLPGVYSLTANSIDEIIARDYII-----NEKPDLVVNIV 93 Query: 130 DGQTREH----ALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKT 185 D E L +G L++A+NKMD ++ I + K +G Sbjct: 94 DATALERNLYLTLQLMEMGA-NLLLALNKMDL-----AKSLGIEIDVDKLEKILG----- 142 Query: 186 VPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAI 230 V VP+S + E +K + + ++ I Sbjct: 143 VKVVPLSAAKKMGIEELKKAISIAVKDKKTAEIKYPNFEPYIKKI 187 >2KE5-A nrPDB Length = 174 Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 43/120 (35%), Gaps = 13/120 (10%) Query: 81 ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLA 140 + + Q+ ++D G D+ + +L+ + + + RE L Sbjct: 47 DGEEVQIDILDTAGLEDYAAIRDNYFRSGEGFLLVFSITE---HESFTATAEFREQILRV 103 Query: 141 FTLGVR-QLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNM 199 + L+V NK D E R Q V+E + ++ G V +V S N+ Sbjct: 104 KAEEDKIPLLVVGNKSDL----EERRQVPVEEARSKAEEWG-----VQYVETSAKTRANV 154 >6GDG-D nrPDB Length = 248 Score = 33.7 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 34/110 (30%), Gaps = 3/110 (2%) Query: 78 WKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHA 137 KF+ K + D G RD + I + I ++ ++ + Sbjct: 74 TKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNLFKSIWNN 133 Query: 138 LLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVP 187 T+ V I+ +NK D + + +++ + P Sbjct: 134 RWLRTISV---ILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATP 180 >4ZI3-A nrPDB Length = 190 Score = 33.3 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 25/195 (12%), Positives = 54/195 (27%), Gaps = 43/195 (22%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 + ++++G ++GK+T L + D Sbjct: 17 EVRILLLGLDNAGKTTLLKQLASE------------------------------DISHIT 46 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 +G I ++ +++ V D G R + D I +I Sbjct: 47 PTQGFNIKS----VQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSAD---RKR 99 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 + GQ L L +++ NK D + + E + + + Sbjct: 100 FEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPA------SEIAEGLNLHTIRDRVW 153 Query: 187 PFVPISGWNGDNMIE 201 S G+ + + Sbjct: 154 QIQSCSALTGEGVQD 168 >2ERY-A nrPDB Length = 172 Score = 33.3 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 33/100 (33%), Gaps = 8/100 (8%) Query: 72 TIDIALWK---FETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV-GEFEAGI 127 TI+ + K + ++ ++D G +F + +L+ + G FE Sbjct: 37 TIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIY 96 Query: 128 SKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQE 167 Q L +I+ NK D + +E Sbjct: 97 KFQRQ----ILRVKDRDEFPMILIGNKADLDHQRQVTQEE 132 >1JGC-A nrPDB Length = 161 Score = 32.9 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 36/107 (33%), Gaps = 10/107 (9%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 M K+ ++ +GH D +++ G + + ++ A Sbjct: 40 MAKKSREESIEEMGHADK----IIARILFLEGHPNLQKLDPLRIGEGPRETLECDLAGEH 95 Query: 61 DKLKAERERGITIDIALWKFETPKYQVT---VIDAPGHRDFIKNMIT 104 D LK RE D + + + D GH DF++ I+ Sbjct: 96 DALKLYRE---ARDYCAEVGDIVSKNIFESLITDEEGHVDFLETQIS 139 >4HI0-E nrPDB Length = 199 Score = 32.9 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 32/192 (16%), Positives = 54/192 (28%), Gaps = 49/192 (25%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 + + V G V SGK+ L + + E + K + + Sbjct: 1 MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMP------ 54 Query: 67 RERGITIDIA-------------------LWKFETPKYQVTVIDAPG---HRDFIKNMIT 104 RER I ++ P ++ +I++ G F + Sbjct: 55 RERIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPEL-- 112 Query: 105 GTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDS---VKWD 161 AD I +I G+ G TR L +NK+D V D Sbjct: 113 ----ADFTIFVIDVAEGDKIPRKGGPGITRSDLL------------VINKIDLAPYVGAD 156 Query: 162 ESRFQEIVKETS 173 + K+ Sbjct: 157 LKVMERDSKKMR 168 >5YMX-A nrPDB Length = 203 Score = 32.9 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 39/143 (27%), Gaps = 19/143 (13%) Query: 19 GKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALW 78 GK+T ++ +K E K + + + L RG Sbjct: 24 GKTTNLQYI------YNKTAAETKGKLISLSTETDRTLFFDFLPLSLGEIRGF------- 70 Query: 79 KFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHAL 138 K + + PG + + D + + + EA + R + Sbjct: 71 -----KTRFHLYTVPGQVFYDASRKLILKGVDGVVFVADSQIERMEANMESLENLRINLA 125 Query: 139 -LAFTLGVRQLIVAVNKMDSVKW 160 + L ++ NK D Sbjct: 126 EQGYDLNKIPYVIQYNKRDLPNA 148 >4GDF-A nrPDB Length = 497 Score = 32.5 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%) Query: 14 GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 G +DSGK+T L+ CGG ++ ELG ++ V + +K Sbjct: 296 GPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVK 346 >1SVL-A nrPDB Length = 377 Score = 32.5 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%) Query: 14 GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK 64 G +DSGK+T L+ CGG ++ ELG ++ V + +K Sbjct: 176 GPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVK 226 >2WJI-A nrPDB Length = 165 Score = 32.5 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 38/188 (20%), Positives = 59/188 (31%), Gaps = 51/188 (27%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERER 69 + +IG+ + GKST L G+ + W Sbjct: 6 IALIGNPNVGKSTIFNALT---------------------GENVYIGNWP---------- 34 Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 G+T++ +FE + V+D PG N I D I Sbjct: 35 GVTVEKKEGEFEYNGEKFKVVDLPGVYSLTANSIDEIIARDYII-----NEKPDLVVNIV 89 Query: 130 DGQTREH----ALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKT 185 D E L +G L++A+NKMD ++ I + K +G Sbjct: 90 DATALERNLYLTLQLMEMGA-NLLLALNKMDL-----AKSLGIEIDVDKLEKILG----- 138 Query: 186 VPFVPISG 193 V VP+S Sbjct: 139 VKVVPLSA 146 >6HA8-V nrPDB Length = 548 Score = 32.5 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 63/422 (14%), Positives = 135/422 (31%), Gaps = 56/422 (13%) Query: 10 VVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE- 68 + +IG +GKST + + + K K A + + D+ AE++ Sbjct: 39 IGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAA--YSFADQTPAEKKL 96 Query: 69 ---------------RGITIDIALWKFETPKYQVTVIDAP-GHRD--FIKNMITGTSQAD 110 G + L K + + ++D P H D ++ +I + Sbjct: 97 LEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDQPTNHLDEKSLQFLIQQLKHYN 156 Query: 111 CAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDE-SRFQEIV 169 +++++ + +K + L+ F + K + E + Q++V Sbjct: 157 GTVILVSHDRYFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMV 216 Query: 170 KETSNFIKKVGYNPKTVP-----------FVPISGWNGDNMIEATTNAPWYKGWEKETKA 218 + + + + + + D I + K EK Sbjct: 217 ERIEAQMNGLASWSEKAHAQSTKKEGFKEYHRVKAKRTDAQI-KSKQKRLEKELEKAKAE 275 Query: 219 GVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTF 278 V T+ +ID + T K L +Q+V K G T+ T I+ G V Sbjct: 276 PVTPEYTVRFSIDT----THKTGKRF-LEVQNVTKAFGERTLFKNANFT--IQHGEKVAI 328 Query: 279 APAGVT--TEVKSVEMHHEQLE---QGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPK 333 + T + ++ + E E P N+G+ + V ++ + + Sbjct: 329 IGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVF-------DLPLEQTPEELF 381 Query: 334 GCASFNATVIV---LNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPK 390 +F A V + H G +A ++ + + + + + + L+ Sbjct: 382 ENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDQPTN 441 Query: 391 FL 392 L Sbjct: 442 HL 443 >3T1O-A nrPDB Length = 198 Score = 32.5 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 24/87 (27%), Gaps = 1/87 (1%) Query: 84 KYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALL-AFT 142 K + + PG + + D + + A RE+ T Sbjct: 73 KTRFHLYTVPGQVFYNASRKLILRGVDGIVFVADSAPNRLRANAESMRNMRENLAEYGLT 132 Query: 143 LGVRQLIVAVNKMDSVKWDESRFQEIV 169 L +++ VNK D V Sbjct: 133 LDDVPIVIQVNKRDLPDALPVEMVRAV 159 >3BH6-A nrPDB Length = 164 Score = 32.1 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 25/195 (12%), Positives = 54/195 (27%), Gaps = 43/195 (22%) Query: 7 HINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 + ++++G ++GK+T L + D Sbjct: 4 EVRILLLGLDNAGKTTLLKQLASE------------------------------DISHIT 33 Query: 67 RERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAG 126 +G I ++ +++ V D G R + D I +I Sbjct: 34 PTQGFNIKS----VQSQGFKLNVWDIGGLRKIRPYWRSYFENTDILIYVIDSAD---RKR 86 Query: 127 ISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTV 186 + GQ L L +++ NK D + + E + + + Sbjct: 87 FEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPA------SEIAEGLNLHTIRDRVW 140 Query: 187 PFVPISGWNGDNMIE 201 S G+ + + Sbjct: 141 QIQSCSALTGEGVQD 155 >5CM8-B nrPDB Length = 203 Score = 31.7 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 20/156 (12%), Positives = 50/156 (32%), Gaps = 15/156 (9%) Query: 46 AAELGKGSFKYAWVLDKLKA--ERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMI 103 + +GK + ++ D+ E + + + + + Q+ ++D G D+ Sbjct: 21 SGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVV-LDGEEVQIDILDTAGQEDYAAIRD 79 Query: 104 TGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDES 163 + + + + + + RE L ++ NK D + Sbjct: 80 NYFRSGEGFLCVFSITD---DESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKV 136 Query: 164 RFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNM 199 E ++ + VP+V S +N+ Sbjct: 137 PLSECQ------LRAQQWA---VPYVETSAKTRENV 163 >5G41-A nrPDB Length = 223 Score = 31.7 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 33/83 (39%), Gaps = 1/83 (1%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +N+V++G +GK T ++ K G T + F E + K +DK + Sbjct: 1 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVP 60 Query: 68 ERGITIDIALWKFETPKYQVTVI 90 + +TI I + + + Sbjct: 61 DE-VTIGIVRERLSKDDCKKGFL 82 >5X6J-A nrPDB Length = 217 Score = 31.7 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDK---LK 64 +N+V++G +GK T ++ K G T + F E + K +D+ + Sbjct: 1 MNIVLMGLPGAGKGTQADRIVEKYGIPHISTGDMFRAAIQEGTELGVKAKSFMDQGALVP 60 Query: 65 AERERGI 71 E GI Sbjct: 61 DEVTIGI 67 >4MIT-A nrPDB Length = 186 Score = 31.7 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 50/130 (38%), Gaps = 10/130 (7%) Query: 82 TPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAF 141 T + Q+ + D G ++ + + S + +I +I V + + T+ H + Sbjct: 55 TRQIQLALWDTAGLEEY--DQLRPLSYSSASIFLICFSVT--SSVSYDNVITKWHPEVIH 110 Query: 142 TLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFI-----KKVGYNPKTVPFVPISGWNG 196 +I+ K+D + D + + + ++ I +++ K V ++ S Sbjct: 111 FAPKVPIILVGTKLD-TRNDPAIVKRLTEQGMTVINTAKGEELKNRIKAVKYIECSAKTS 169 Query: 197 DNMIEATTNA 206 +N+ A Sbjct: 170 ENLKTVFDEA 179 >4V7F-o nrPDB Length = 647 Score = 31.7 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 53/160 (33%), Gaps = 12/160 (7%) Query: 48 ELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTS 107 +GK SF + + T + + F+ + ID PG D + Sbjct: 177 NVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIE 236 Query: 108 QADCAIL------IIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWD 161 + ++ + G + + Q + + + ++V +NK D ++ Sbjct: 237 MQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIR-- 294 Query: 162 ESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIE 201 E + +K+V V + S +N++E Sbjct: 295 PEDLDEERAQLLESVKEV----PGVEIMTSSCQLEENVME 330 >5EE0-A nrPDB Length = 395 Score = 31.7 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 27/193 (13%), Positives = 61/193 (31%), Gaps = 12/193 (6%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVL 60 +G+ SH+ + ++G + GKST + + + A + ++ W+ Sbjct: 19 LGRFSSHLKIGIVGLPNVGKSTFFNIVTKLSIPAENFPFCTIDPNEARVYVPDERFDWLC 78 Query: 61 DKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGV 120 K + E ++I A ++ D ++ Sbjct: 79 QLYKPKSEVSAYLEINDIAGLVRG-------AHAGEGLGNAFLSHIRAVDGIFHVLRAFE 131 Query: 121 GEFEAGISKDGQ-TREHALLAFTLGVRQLIVAVNKMDSVKWDESRF----QEIVKETSNF 175 + I R+ + L ++ + NK+D ++ R ++ E Sbjct: 132 DKEVTHIDDSVDPVRDLETIGEELRLKDIEFVQNKIDDLEKSMKRSNDKQLKLEHELCEK 191 Query: 176 IKKVGYNPKTVPF 188 +K + K V F Sbjct: 192 VKAHLEDGKDVRF 204 >4WED-A nrPDB Length = 525 Score = 31.7 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 37/252 (14%), Positives = 71/252 (28%), Gaps = 16/252 (6%) Query: 91 DAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIV 150 D P + +I A+ G + G T E G ++ Sbjct: 213 DKPTYERLEAKVIPDARSRVAALR---AGEIDLVGGFWIAPLTPEEGKQLEAAGFNVVVD 269 Query: 151 AVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYK 210 N + ++ R + + +G + + V G+ + P+ Sbjct: 270 PGNVTLVMAFNPDRAEPLKDPQVRKAVSIGIDRAAISKVLYHGYAKPAGNMFSAALPYAG 329 Query: 211 GWEKETKAGVVKGKTLLEAIDAIEQPSRPTD-KPLRL-PLQDVYKIGGIGTVPVGRVETG 268 LLE P R D KPL L + + G V +++ Sbjct: 330 KQFDAPVRDAAAASALLEKAGWTGSPIRSKDGKPLTLELVVSPDAVPGS-RVIAEVIQSE 388 Query: 269 VIKPGMVVTFAPAGVTTEVKSVEMHHE----QLEQGVP----GDNVGFNVKNVSVKEIRR 320 + + G+ + ++ + L G P G V + + ++ Sbjct: 389 MKEVGIDLVIRSVDHASKHTDMLEQKYDLGFFLTYGAPYDPFGSLVALCL-STFKNDVE- 446 Query: 321 GNVCGDAKNDPP 332 G + D N P Sbjct: 447 GKLVTDPVNLDP 458 >5DE3-A nrPDB Length = 169 Score = 31.7 bits (70), Expect = 0.76, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 42/158 (26%), Gaps = 11/158 (6%) Query: 49 LGKGSFKYAWVLDKLKAERERGITIDIAL--WKFETPKYQVTVIDAPGHRDFIKNMITGT 106 LG + +L L E IT + + + D G + Sbjct: 6 LGLDNAGKTTILKALSEEDITTITPTQGFNIKSLSRDGFNLKIWDIGGQKSIRPYWRNYF 65 Query: 107 SQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQ 166 Q D I +I + + + L + L+V NK D V + Sbjct: 66 DQTDALIYVIDSADSKRLSESEFE---LTELLQEEKMTGVPLLVFANKQDLVGALAA--- 119 Query: 167 EIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATT 204 E ++ + + S G + E Sbjct: 120 ---DEIASTLDLTSIRDRPWQIQACSAKQGTGLKEGME 154 >3IBY-A nrPDB Length = 256 Score = 31.4 bits (69), Expect = 0.82, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 33/89 (37%), Gaps = 2/89 (2%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 G+T++ +F ++ + + D PG + N + A + + + Sbjct: 33 GVTVEKKTGEFLLGEHLIEITDLPGVYSLVANAEGISQDEQIAAQSVIDLEYDCIINVID 92 Query: 130 DGQTREHALLAFTLGV--RQLIVAVNKMD 156 H L L + ++VA+N MD Sbjct: 93 ACHLERHLYLTSQLFELGKPVVVALNMMD 121 >3CON-A nrPDB Length = 190 Score = 31.4 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 20/134 (14%), Positives = 41/134 (30%), Gaps = 16/134 (11%) Query: 72 TIDIALWK---FETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGIS 128 TI+ + K + + ++D G ++ + + + A + A I+ Sbjct: 53 TIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADIN 112 Query: 129 KDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPF 188 RE +++ NK D K+ K G +PF Sbjct: 113 LY---REQIKRVKDSDDVPMVLVGNKCDLPTRTVDT-----KQAHELAKSYG-----IPF 159 Query: 189 VPISGWNGDNMIEA 202 + S + +A Sbjct: 160 IETSAKTRQGVEDA 173 >3NXS-A nrPDB Length = 329 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 37/232 (15%), Positives = 75/232 (32%), Gaps = 28/232 (12%) Query: 1 MGKEKSHINVVVIGHVDSGKSTTTGHL-IYKCGGIDKRTIEKFEKEAAELGKGSFKYAWV 59 M + S ++V + G GKSTT L ++ + + + + G Sbjct: 51 MPEAGSAMHVGITGVPGVGKSTTIEALGMHLIEAGHRVAVLAVDPSSTRTGGSILGDKTR 110 Query: 60 LDKLKAERERGI----TIDIALWKFETPKYQVTVIDAPGHRDFIKNM-------ITGTSQ 108 + +L + I T + + + +++A G+ + +T Sbjct: 111 MARLAVHPDAYIRPSPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEVTVAGM 170 Query: 109 ADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEI 168 D + + G+ GI K LA ++ VNK D E++ Sbjct: 171 VDTFVFLTLARTGDQLQGIKKG-----VLELAD-------VIVVNKADGEHAVEAKAAA- 217 Query: 169 VKETSNFIKKVGYNPKTV--PFVPISGWNGDNMIEATTNAPWYKGWEKETKA 218 +E S I+ + P + +S G + E ++ +E Sbjct: 218 -RELSGAIRLIYPRESLWRPPVLTMSAVEGTGLPELWETVLRHREVLEEAGE 268 >5IRR-A nrPDB Length = 308 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 34/97 (35%), Gaps = 21/97 (21%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 +K +I ++V+G GK+T LI G E ++ GS+ + Sbjct: 23 KKKYIKLIVVGDSGLGKTTLIKSLISIPG------------ERLQVHDGSYTPTEQFRRD 70 Query: 64 KAERERGITIDIALWKFETPKYQV---TVIDAPGHRD 97 ++ + + + + D PG+ D Sbjct: 71 PE------SLSSTVSWRDEEDRVIWVYKIQDTPGYGD 101 >5UHV-A nrPDB Length = 166 Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 17/122 (13%), Positives = 36/122 (29%), Gaps = 13/122 (10%) Query: 81 ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLA 140 + + ++D G ++ + + + A + A I+ RE Sbjct: 47 DGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLY---REQIKRV 103 Query: 141 FTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMI 200 +++ NK D K+ K G +PF+ S + Sbjct: 104 KDSDDVPMVLVGNKCDLPTRTVDT-----KQAHELAKSYG-----IPFIETSAKTRQGVE 153 Query: 201 EA 202 +A Sbjct: 154 DA 155 >3N05-A nrPDB Length = 590 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 49/121 (40%), Gaps = 6/121 (4%) Query: 147 QLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNA 206 QL +A+N++DS D + E + + + G + P + ++G+ +++ ++ Sbjct: 4 QLRLALNQIDSTVGDIAGNAEAILRWTRHSAEQGAHLVAFPEMALTGYPVEDLALRSSFV 63 Query: 207 PWYKGWEKE-----TKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVP 261 + +E + G + L+ +D E +P P ++ + G V Sbjct: 64 EASRTALRELAARLAEEGFGELPVLVGYLDRSESAQPKYGQPAGAP-RNAAAVLHRGRVA 122 Query: 262 V 262 + Sbjct: 123 L 123 >3A1U-A nrPDB Length = 258 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 66/178 (37%), Gaps = 15/178 (8%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 G+T++ F Y + +ID PG + I D +L + A Sbjct: 37 GVTVEKKEGVFTYKGYTINLIDLPGTYSLGYSSIDEKIARD-YLLKGDADLVILVADSVN 95 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 Q+ + LL +++I+A+ +D E++ + + K +G +P V Sbjct: 96 PEQSL-YLLLEILEMEKKVILAMTAID-----EAKKTGMKIDRYELQKHLG-----IPVV 144 Query: 190 PISGWNGDNMIEATTN-APWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRL 246 S G+ + E + + + + G+ + I +E R DK LR+ Sbjct: 145 FTSSVTGEGLEELKEKIVEYAQKNTILHRMILDYGEKVESEIKKVENFLR--DKKLRI 200 >3IIK-A nrPDB Length = 180 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 31/90 (34%), Gaps = 8/90 (8%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK---- 64 N+++ G GK+T L K G + +E G +LD+ + Sbjct: 13 NILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQLYDGYDEEYDCPILDEDRVVDE 72 Query: 65 ---AERERGITIDI-ALWKFETPKYQVTVI 90 RE G+ +D F + + + Sbjct: 73 LDNQMREGGVIVDYHGCDFFPERWFHIVFV 102 >4PHF-A nrPDB Length = 184 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 34/205 (16%), Positives = 70/205 (34%), Gaps = 37/205 (18%) Query: 2 GKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLD 61 ++K+ + V+++G GK++ + + + E+ K A + Sbjct: 5 SRKKNILKVIILGDSGVGKTSLMHRYVNDKYSCQYKATIGADFLTKEVTVDGDKVATMQV 64 Query: 62 KLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIA-GGV 120 A +ER ++ +A ++ ADC +L+ Sbjct: 65 WDTAGQERFQSLGVAFYRG----------------------------ADCCVLVYDVTNA 96 Query: 121 GEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVG 180 FE S + HA + +I+ NK+D+ ++IV E S +++ Sbjct: 97 SSFENIKSWRDEFLVHANVNSPETFPFVILG-NKIDA-----EESKKIVSEKSA--QELA 148 Query: 181 YNPKTVPFVPISGWNGDNMIEATTN 205 + +P S N N+ A Sbjct: 149 KSLGDIPLFLTSAKNAINVDTAFEE 173 >2QSZ-A nrPDB Length = 207 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 10 VVVIGHVDSGKSTTTGHL---IYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAE 66 + + G +SGK+T +L + C I + K E E E K F VL+ L E Sbjct: 24 IGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEI-ETDKNGFLQYDVLEALNME 82 Query: 67 R 67 + Sbjct: 83 K 83 >3Q72-A nrPDB Length = 166 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 24/75 (32%), Gaps = 12/75 (16%) Query: 93 PGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAV 152 PGH + D +++ + + K + R A +I+ Sbjct: 66 PGH---------CMAMGDAYVIVYSVTD---KGSFEKASELRVQLRRARQTDDVPIILVG 113 Query: 153 NKMDSVKWDESRFQE 167 NK D V+ E E Sbjct: 114 NKSDLVRSREVSVDE 128 >5G3Y-A nrPDB Length = 226 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +N++++G +GK T ++ + G T + F E + K +DK + Sbjct: 1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVP 60 Query: 68 ERGITIDIALWKFETPKYQVTVI 90 + +TI + + P + + Sbjct: 61 DE-VTIGLVKERLSQPDCKKGFL 82 >2FN4-A nrPDB Length = 181 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 10/72 (13%), Positives = 23/72 (31%), Gaps = 3/72 (4%) Query: 86 QVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGV 145 ++ ++D G +F +L+ A ++ G+ L Sbjct: 58 RLDILDTAGQEEFGAMREQYMRAGHGFLLVFAIND---RQSFNEVGKLFTQILRVKDRDD 114 Query: 146 RQLIVAVNKMDS 157 +++ NK D Sbjct: 115 FPVVLVGNKADL 126 >4WA7-A nrPDB Length = 170 Score = 30.2 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 14/122 (11%), Positives = 33/122 (27%), Gaps = 13/122 (10%) Query: 81 ETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLA 140 + + ++D G ++ + + + A RE Sbjct: 48 DGETCLLDILDTAGLEEYSAMRDQYMRTGEGFLCVFAINN---TKSFEDIHHYREQIKRV 104 Query: 141 FTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMI 200 +++ NK D K+ + + G +PF+ S + Sbjct: 105 KDSEDVPMVLVGNKCDLPSRTVDT-----KQAQDLARSYG-----IPFIETSAKTRQGVD 154 Query: 201 EA 202 +A Sbjct: 155 DA 156 >1Z22-A nrPDB Length = 168 Score = 30.2 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 12/91 (13%), Positives = 29/91 (31%), Gaps = 5/91 (5%) Query: 78 WKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHA 137 + ++ + D G +F A +L+ + E S + + Sbjct: 47 IQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRE-----SFEAISSWRE 101 Query: 138 LLAFTLGVRQLIVAVNKMDSVKWDESRFQEI 168 + +G + NK+D + + +E Sbjct: 102 KVVAEVGDIPTALVQNKIDLLDDSCIKNEEA 132 >4M9Q-A nrPDB Length = 227 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 17/121 (14%), Positives = 38/121 (31%), Gaps = 5/121 (4%) Query: 45 EAAELGKGSFKYAWVLDKLKAERERGITIDIAL--WKFETPKYQVTVIDAPGHRDFIKNM 102 A LG + +L+ ++ E +R T KY++ V D G ++ Sbjct: 6 TIALLGLDNAGKTTLLNSIQGEVDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVW 65 Query: 103 ITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDE 162 ++ + ++ + T L + + + + NK D Sbjct: 66 KKYLAEVHAIVYVVDAAD---PGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAP 122 Query: 163 S 163 + Sbjct: 123 A 123 >5DI3-B nrPDB Length = 263 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 17/121 (14%), Positives = 38/121 (31%), Gaps = 5/121 (4%) Query: 45 EAAELGKGSFKYAWVLDKLKAERERGITIDIAL--WKFETPKYQVTVIDAPGHRDFIKNM 102 A LG + +L+ ++ E +R T KY++ V D G ++ Sbjct: 6 TIALLGLDNAGKTTLLNSIQGEVDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVW 65 Query: 103 ITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDE 162 ++ + ++ + T L + + + + NK D Sbjct: 66 KKYLAEVHAIVYVVDAAD---PGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAP 122 Query: 163 S 163 + Sbjct: 123 A 123 >2ZOY-A nrPDB Length = 185 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 24/58 (41%), Gaps = 2/58 (3%) Query: 42 FEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFI 99 + A+ + + ER R + + +A + + + +IDAP H DF+ Sbjct: 55 MHELLADDWDKELRDITRDPEDPLERLRAVVVTLA--ENVSRPELLLLIDAPSHPDFL 110 >4QBG-B nrPDB Length = 217 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 29/68 (42%), Gaps = 1/68 (1%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +N+V++G +GK T ++ K G T + F E + +DK + Sbjct: 1 MNIVLMGLPGAGKGTQAERIVAKYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 68 ERGITIDI 75 + +TI I Sbjct: 61 DE-VTIGI 67 >1F6B-A nrPDB Length = 198 Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 19/137 (13%), Positives = 45/137 (32%), Gaps = 7/137 (5%) Query: 33 GIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDA 92 G+ K+T + GK + + D+L T+ + T D Sbjct: 20 GLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVP---TLHPTSEELTIAGMTFTTFDL 76 Query: 93 PGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAV 152 GH + + + ++ + + + + + T+ +++ Sbjct: 77 GGHIQARRVWKNYLPAINGIVFLVDCAD---HERLLESKEELDSLMTDETIANVPILILG 133 Query: 153 NKMDSVKW-DESRFQEI 168 NK+D + E R +E+ Sbjct: 134 NKIDRPEAISEERLREM 150 >4MKI-B nrPDB Length = 298 Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 11/18 (61%) Query: 10 VVVIGHVDSGKSTTTGHL 27 V +IGH SGKST L Sbjct: 40 VGIIGHTGSGKSTLIQQL 57 >4FID-A nrPDB Length = 340 Score = 29.8 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 42/116 (36%), Gaps = 11/116 (9%) Query: 61 DKLKAERE----RGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILII 116 D + E + R T I + F +ID G R K ++ S DCAI + Sbjct: 133 DYVPTEEDLIHNRTKTTGIHEYDFVVKDIPFHLIDVGGQRSERKKWVSFFSDVDCAIFVT 192 Query: 117 AGGVGEFEAGISKDGQ--TREHALLAFTLGVRQL-----IVAVNKMDSVKWDESRF 165 + + + + T A+ + L ++ +NKMD + ++ Sbjct: 193 SLAEYDMKLYEDGNTSRLTESIAVFKDIMTNEFLKGAVKLIFLNKMDLFEEKLTKV 248 >4MKG-A nrPDB Length = 217 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 29/68 (42%), Gaps = 1/68 (1%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +N+V++G +GK T ++ K G T + F E + +DK + Sbjct: 1 MNIVLMGLPGAGKGTQAERIVEKYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 68 ERGITIDI 75 + +TI I Sbjct: 61 DE-VTIGI 67 >1VIA-A nrPDB Length = 175 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 24/60 (40%) Query: 9 NVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERE 68 N+V IG + SGKST L + + E++ + F+ + E++ Sbjct: 6 NIVFIGFMGSGKSTLARALAKDLDLVFLDSDFLIEQKFNQKVSEIFEQKRENFFREQEQK 65 >6N8J-m nrPDB Length = 486 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 27/76 (35%), Gaps = 1/76 (1%) Query: 19 GKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALW 78 GK + L+ + + + G L K K + I + +W Sbjct: 295 GKGSLI-QLLRQFSQLHTDRKQISVGFIGYPNTGKSSIINTLRKKKVCQVAPIPGETKVW 353 Query: 79 KFETPKYQVTVIDAPG 94 ++ T ++ +ID PG Sbjct: 354 QYITLMKRIFLIDCPG 369 >4M8N-E nrPDB Length = 199 Score = 29.1 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 23/80 (28%), Gaps = 3/80 (3%) Query: 78 WKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHA 137 + + + + ++D G F L+ + + + RE Sbjct: 47 VEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQ---STFNDLQDLREQI 103 Query: 138 LLAFTLGVRQLIVAVNKMDS 157 L +I+ NK D Sbjct: 104 LRVKDTDDVPMILVGNKCDL 123 >4DXA-A nrPDB Length = 169 Score = 29.1 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 23/80 (28%), Gaps = 3/80 (3%) Query: 78 WKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHA 137 + + + + ++D G F L+ + + + RE Sbjct: 46 VEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQ---STFNDLQDLREQI 102 Query: 138 LLAFTLGVRQLIVAVNKMDS 157 L +I+ NK D Sbjct: 103 LRVKDTDDVPMILVGNKCDL 122 >3A1W-A nrPDB Length = 168 Score = 29.1 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 51/140 (36%), Gaps = 12/140 (8%) Query: 70 GITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISK 129 G+T++ F Y + +ID PG + I D +L + A Sbjct: 37 GVTVEKKEGVFTYKGYTINLIDLPGTYSLGYSSIDEKIARD-YLLKGDADLVILVADSVN 95 Query: 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFV 189 Q+ + LL +++I+A+ +D E++ + + K +G +P V Sbjct: 96 PEQSL-YLLLEILEMEKKVILAMTAID-----EAKKTGMKIDRYELQKHLG-----IPVV 144 Query: 190 PISGWNGDNMIEATTNAPWY 209 S G+ + E Y Sbjct: 145 FTSSVTGEGLEELKEKIVEY 164 >1U0L-A nrPDB Length = 301 Score = 29.1 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 34/99 (34%), Gaps = 15/99 (15%) Query: 106 TSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRF 165 + D IL++ + E I + L+ + ++ +NKMD D+ R Sbjct: 82 VANVDQVILVVTVKMPETSTYI------IDKFLVLAEKNELETVMVINKMDLYDEDDLRK 135 Query: 166 QEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATT 204 ++E + + P V S G + E Sbjct: 136 VRELEEIYSGL---------YPIVKTSAKTGMGIEELKE 165 >4HUQ-A nrPDB Length = 290 Score = 29.1 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 10 VVVIGHVDSGKSTTTGHL 27 + +IGH SGKST L Sbjct: 36 LAIIGHTGSGKSTLIQQL 53 >6FT6-s nrPDB Length = 520 Score = 29.1 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 35/86 (40%), Gaps = 15/86 (17%) Query: 115 IIAGGVG---EFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 +I +A + ++R+ ++LI+ +NK+D + ++++ Sbjct: 172 VIDASDVILYVLDARDPESTRSRKVEEAVLQSQGKRLILILNKVDLIPP------HVLEQ 225 Query: 172 TSNFIKKVGYNPKTVPFVPISGWNGD 197 N++K + P +P+ +G Sbjct: 226 WLNYLK------SSFPTIPLRASSGA 245 >2P3S-A nrPDB Length = 217 Score = 28.7 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 8 INVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAER 67 +N+V++G +GK T ++ G T + F E + +DK + Sbjct: 1 MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 68 ERGITIDI 75 + +TI I Sbjct: 61 DE-VTIGI 67 >2P65-A nrPDB Length = 187 Score = 28.7 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 24/53 (45%) Query: 218 AGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVI 270 AG E + +I + + + + + + +++ + G G V G ++ G I Sbjct: 91 AGAKYRGDFEERLKSILKEVQDAEGQVVMFIDEIHTVVGAGAVAEGALDAGNI 143 >5JRH-A nrPDB Length = 660 Score = 28.3 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 23/69 (33%) Query: 318 IRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKN 377 I++G+V P+ + A + I G+SP + + Sbjct: 129 IKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADE 188 Query: 378 DRRSGKKLE 386 R+G+ + Sbjct: 189 GVRAGRSIP 197 >3TRF-A nrPDB Length = 185 Score = 28.3 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 27/65 (41%) Query: 4 EKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKL 63 +K+ N+ +IG + +GK++ L I + ++ EK F+ Sbjct: 2 KKNLTNIYLIGLMGAGKTSVGSQLAKLTKRILYDSDKEIEKRTGADIAWIFEMEGEAGFR 61 Query: 64 KAERE 68 + ERE Sbjct: 62 RRERE 66 >1XRT-A nrPDB Length = 467 Score = 27.9 bits (60), Expect = 9.9, Method: Composition-based stats. Identities = 24/149 (16%), Positives = 44/149 (29%), Gaps = 15/149 (10%) Query: 265 VETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKN-VSVKEIRRGNV 323 VE G IK P + K + + ++ +V ++I G+ Sbjct: 71 VENGKIKKIDKNILVPEAEIIDAKGLIVCPGFIDI-----HVHLRDPGQTYKEDIESGSR 125 Query: 324 CGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGK 383 C A F V + N I + V + +L G+ Sbjct: 126 CAVAG--------GFTTIVCMPNTNPPIDNT-TVVNYILQKSKSVGLCRVLPTGTITKGR 176 Query: 384 KLEDHPKFLKSGDAALVKFVPSKPMCVEA 412 K ++ F +A V F +++ Sbjct: 177 KGKEIADFYSLKEAGCVAFTDDGSPVMDS 205 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.118 0.296 Lambda K H 0.267 0.0367 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,091,960 Number of Sequences: 36641 Number of extensions: 560244 Number of successful extensions: 2824 Number of sequences better than 10.0: 182 Number of HSP's better than 10.0 without gapping: 198 Number of HSP's successfully gapped in prelim test: 96 Number of HSP's that attempted gapping in prelim test: 1993 Number of HSP's gapped (non-prelim): 394 length of query: 458 length of database: 10,336,785 effective HSP length: 100 effective length of query: 358 effective length of database: 6,672,685 effective search space: 2388821230 effective search space used: 2388821230 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.9 bits)