BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P02794 (183 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3AJP-A nrPDB 378 e-106 5GN8-A nrPDB 362 e-101 5JKM-A nrPDB 358 e-100 3WNW-A nrPDB 354 1e-98 5OBB-A nrPDB 351 1e-97 1R03-A nrPDB 305 5e-84 5GN8-B nrPDB 300 3e-82 1BG7-A nrPDB 265 9e-72 6I36-A nrPDB 253 3e-68 5WPN-A nrPDB 241 1e-64 1RCD-A nrPDB 241 1e-64 6A4U-A nrPDB 221 1e-58 4V6B-AA nrPDB 215 8e-57 2V2I-A nrPDB 208 1e-54 1H96-A nrPDB 207 2e-54 3A68-A nrPDB 164 2e-41 3VNX-A nrPDB 138 2e-33 5LS9-A nrPDB 106 6e-24 1Z6O-M nrPDB 97 5e-21 1S3Q-A nrPDB 89 1e-18 1Z4A-A nrPDB 84 4e-17 2JD8-0 nrPDB 83 6e-17 4ZL6-B nrPDB 70 4e-13 1KRQ-A nrPDB 49 1e-06 4CMY-A nrPDB 48 3e-06 3OJ5-A nrPDB 47 4e-06 1Z6O-A nrPDB 44 4e-05 3QZ3-A nrPDB 43 7e-05 5C6F-A nrPDB 40 5e-04 5U1A-A nrPDB 35 0.015 4ZTT-A nrPDB 35 0.024 5TFQ-A nrPDB 28 1.9 4LJY-A nrPDB 28 2.0 3FMC-A nrPDB 28 3.1 4X4R-A nrPDB 27 3.7 2DTU-A nrPDB 27 4.5 4E6K-A nrPDB 26 9.4 >3AJP-A nrPDB Length = 182 Score = 378 bits (970), Expect = e-106, Method: Compositional matrix adjust. Identities = 181/182 (99%), Positives = 181/182 (99%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH Sbjct: 1 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL Sbjct: 61 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 ATDKNDPHLCDFIETHYLN QVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN Sbjct: 121 ATDKNDPHLCDFIETHYLNAQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 180 Query: 182 ES 183 ES Sbjct: 181 ES 182 >5GN8-A nrPDB Length = 176 Score = 362 bits (928), Expect = e-101, Method: Compositional matrix adjust. Identities = 176/182 (96%), Positives = 176/182 (96%), Gaps = 6/182 (3%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH Sbjct: 1 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL Sbjct: 61 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 ATDKNDPHLCDFIETHYL IKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN Sbjct: 121 ATDKNDPHLCDFIETHYL------IKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 174 Query: 182 ES 183 ES Sbjct: 175 ES 176 >5JKM-A nrPDB Length = 183 Score = 358 bits (919), Expect = e-100, Method: Compositional matrix adjust. Identities = 173/183 (94%), Positives = 174/183 (95%) Query: 1 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 MTTASTSQVRQNYHQDSE AINRQI LELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS Sbjct: 1 MTTASTSQVRQNYHQDSEKAINRQIRLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 HEEREHAEKLMKLQNQRGGRIFLQDI+KPD DDWESGL AME AL LEK VNQSLLELHK Sbjct: 61 HEEREHAEKLMKLQNQRGGRIFLQDIQKPDKDDWESGLRAMEKALKLEKKVNQSLLELHK 120 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD 180 LAT KNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAP SGLAEYLFDKHTLGDSD Sbjct: 121 LATKKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPRSGLAEYLFDKHTLGDSD 180 Query: 181 NES 183 NES Sbjct: 181 NES 183 >3WNW-A nrPDB Length = 212 Score = 354 bits (908), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 168/180 (93%), Positives = 175/180 (97%) Query: 1 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 MTTAS SQVRQNYHQD+EAAINRQINLELYASYVYLSMS YFDRDDVALKNFAKYFLHQS Sbjct: 18 MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQS 77 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 HEEREHAEKLMKLQNQRGGRIFLQDIKKPD DDWESGLNAMECALHLEK+VNQSLLELHK Sbjct: 78 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHK 137 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD 180 LATDKNDPHLCDFIET+YL+EQVK+IKELGDHVTNLRKMGAPE+G+AEYLFDKHTLG D Sbjct: 138 LATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGD 197 >5OBB-A nrPDB Length = 197 Score = 351 bits (900), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 168/179 (93%), Positives = 175/179 (97%) Query: 1 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 MTTAS SQVRQNYHQD+EAAINRQINLELYASYVYLSMS YFDRDDVALKNFAKYFLHQS Sbjct: 1 MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQS 60 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 HEEREHAEKLMKLQNQRGGRIFLQDIKKPD DDWESGLNAMECALHLEK+VNQSLLELHK Sbjct: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHK 120 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 LATDKNDPHLCDFIET+YL+EQVK+IKELGDHVTNLRKMGAPE+G+AEYLFDKHTLG S Sbjct: 121 LATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGGS 179 >1R03-A nrPDB Length = 182 Score = 305 bits (782), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 145/182 (79%), Positives = 163/182 (89%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 A S+VRQN+H DSEAAINRQINLELYASYVYLSM+YYF RDDVAL NF++YFLHQS Sbjct: 1 PAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSR 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EE EHAEKLM+LQNQRGGRI LQDIKKP+ DDWESGL+AMECAL LEKNVNQSLLELH L Sbjct: 61 EETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHAL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 A+DK DPHLCDF+ET+YLNEQVK+IKELGDHV NL KMGAP++GLAEYLFD HTLG+ + Sbjct: 121 ASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTHTLGNENK 180 Query: 182 ES 183 ++ Sbjct: 181 QN 182 >5GN8-B nrPDB Length = 146 Score = 300 bits (768), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 146/152 (96%), Positives = 146/152 (96%), Gaps = 6/152 (3%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH Sbjct: 1 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL Sbjct: 61 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHV 153 ATDKNDPHLCDFIETHYL IKELGDHV Sbjct: 121 ATDKNDPHLCDFIETHYL------IKELGDHV 146 >1BG7-A nrPDB Length = 176 Score = 265 bits (677), Expect = 9e-72, Method: Compositional matrix adjust. Identities = 118/173 (68%), Positives = 150/173 (86%) Query: 7 SQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREH 66 SQVRQN+H+D EAAINR +N+ELYASY YLSM++YFDRDD+AL N AK+F QSHEEREH Sbjct: 3 SQVRQNFHRDCEAAINRMVNMELYASYTYLSMAFYFDRDDIALHNVAKFFKEQSHEEREH 62 Query: 67 AEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKN 126 AEKLMK QN+RGGRI LQD++KP+ D+W + L AM+ AL LEK VNQ+LL+LHK+ +DK Sbjct: 63 AEKLMKDQNKRGGRIVLQDVQKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKVGSDKV 122 Query: 127 DPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 DPHLCDF+ET Y EQVK+IK+LGD++TNL+++G P++G+ EYLFDKHT+G+S Sbjct: 123 DPHLCDFLETEYPEEQVKSIKQLGDYITNLKRLGLPQNGMGEYLFDKHTMGES 175 >6I36-A nrPDB Length = 176 Score = 253 bits (646), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 117/174 (67%), Positives = 142/174 (81%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 SQVRQNYH D EAA+NR +NLELYASY Y SM +FDRDDVAL N A++F SHEERE Sbjct: 2 VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEHSHEERE 61 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 HAEK MK QN+RGGR+ LQDIKKP+ D+W + L AM+ AL LEK VNQ+LL+LHKLATDK Sbjct: 62 HAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDK 121 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 DPHLCDF+E+ YL EQVK IK +GD +TNL+++G PE+G+ EYLFDKH++ +S Sbjct: 122 VDPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKES 175 >5WPN-A nrPDB Length = 171 Score = 241 bits (616), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 114/172 (66%), Positives = 140/172 (81%), Gaps = 3/172 (1%) Query: 5 STSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEER 64 + +Q RQNY D EA IN+QINLELYASYVY SM+++FDRDD+ALK F K+F HQS EER Sbjct: 1 AQTQPRQNYASDVEAGINKQINLELYASYVYQSMAWFFDRDDIALKGFHKFFKHQSEEER 60 Query: 65 EHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATD 124 EHAEKLM+ QN+RGGRI LQDI+KP+ D+W +GL AM+ AL LEKNVNQSLL+LHK+ Sbjct: 61 EHAEKLMQYQNKRGGRIVLQDIQKPERDEWGTGLEAMQVALALEKNVNQSLLDLHKVGAG 120 Query: 125 KNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTL 176 +D HLCDF+E HYL EQVK+IKEL D+VTNL+++G GL EY+FDK +L Sbjct: 121 HDDAHLCDFLEEHYLEEQVKSIKELSDYVTNLKRVG---PGLGEYMFDKESL 169 >1RCD-A nrPDB Length = 173 Score = 241 bits (615), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 106/171 (61%), Positives = 145/171 (84%) Query: 7 SQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREH 66 SQVRQN+HQD EA +NR +NL+ ++SYVYLSM+ YF+RDDVAL NFAK+F +S EE+EH Sbjct: 3 SQVRQNFHQDCEAGLNRTVNLKFHSSYVYLSMASYFNRDDVALSNFAKFFRERSEEEKEH 62 Query: 67 AEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKN 126 AEKL++ QNQRGGR+FLQ ++KP+ DDW +GL A++ AL L+K+VNQ+LL+LH +A DK+ Sbjct: 63 AEKLIEYQNQRGGRVFLQSVEKPERDDWANGLEALQTALKLQKSVNQALLDLHAVAADKS 122 Query: 127 DPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 DPH+ DF+E+ YL+E V+ IK+LGDH+T+L+K+ + G+AEYLF+KHTLG Sbjct: 123 DPHMTDFLESPYLSESVETIKKLGDHITSLKKLWSSHPGMAEYLFNKHTLG 173 >6A4U-A nrPDB Length = 169 Score = 221 bits (563), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 104/168 (61%), Positives = 127/168 (75%), Gaps = 2/168 (1%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 SQVRQNYH+D EA+IN+QIN+ELYASYVYLSM+YYF+RDDVAL FAK+F S EERE Sbjct: 1 ASQVRQNYHEDCEASINKQINMELYASYVYLSMAYYFERDDVALPGFAKFFKESSDEERE 60 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 HA+ MK QN+RGGRI LQ I P +W +GL A++ AL LEK VNQSLLELH A+ Sbjct: 61 HAQTFMKYQNKRGGRIVLQQIAAPSMREWGTGLEALQAALDLEKQVNQSLLELHSTASGN 120 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDK 173 NDPHL +E YL EQV +IK++GD +T L++ G +GL EY+FDK Sbjct: 121 NDPHLTKLLEDEYLEEQVDSIKKIGDMITKLKRAGP--TGLGEYMFDK 166 >4V6B-AA nrPDB Length = 192 Score = 215 bits (548), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 96/174 (55%), Positives = 131/174 (75%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 +SQ+RQNY D EAA+N +NL L ASY YLS+ +YFDRDDVAL+ + +F + E+RE Sbjct: 3 SSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKRE 62 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 E+L+K+QNQRGGR QDIKKP D+W +AM+ A+ LEK +NQ+LL+LH L + + Sbjct: 63 GYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSAR 122 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 DPHLCDF+ETH+L+E+VK IK++GDH+TNL ++G PE+GL EYL K +L + Sbjct: 123 TDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLSSKGSLSST 176 >2V2I-A nrPDB Length = 175 Score = 208 bits (529), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 91/171 (53%), Positives = 134/171 (78%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 +SQ+RQNY + EAA+NR +NL L ASY YLS+ +YFDRDDVAL+ +F + E+RE Sbjct: 2 SSQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALEGVCHFFRELAEEKRE 61 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 AE+L+K+QNQRGGR QD++KP D+W + +AM+ A+ LEK++NQ+LL+LH L + + Sbjct: 62 GAERLLKMQNQRGGRALFQDLQKPSQDEWGTTPDAMKAAIVLEKSLNQALLDLHALGSAQ 121 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTL 176 DPHLCDF+E+H+L+E+VK IK++GDH+TN++++ ++GL EYLF++ TL Sbjct: 122 ADPHLCDFLESHFLDEEVKLIKKMGDHLTNIQRLVGSQAGLGEYLFERLTL 172 >1H96-A nrPDB Length = 182 Score = 207 bits (526), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 94/179 (52%), Positives = 131/179 (73%), Gaps = 8/179 (4%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 TSQ+RQNY + EAA+NR +NL L ASY YLS+ ++FDRDDVAL+ +F + E+RE Sbjct: 1 TSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKRE 60 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 AE+L++ QN RGGR QD++KP D+W AME AL +EKN+NQ+LL+LH L + + Sbjct: 61 GAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSAR 120 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKM--------GAPESGLAEYLFDKHTL 176 DPHLCDF+E+HYL+++VK IK++G+H+TNLR++ GAP+ L EYLF++ TL Sbjct: 121 ADPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFERLTL 179 >3A68-A nrPDB Length = 212 Score = 164 bits (415), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 91/185 (49%), Positives = 116/185 (62%), Gaps = 10/185 (5%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 T S RQ Y +SE+A+N QIN+E SYVY +M YFDRD+VAL+ AK+F S Sbjct: 30 TVPQASLARQKYVDESESAVNEQINVEYNVSYVYHAMFAYFDRDNVALRGLAKFFKESSE 89 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCD----DWESGLNAMECALHLEKNVNQSLLE 117 EEREHAEKLM+ QN+RGG++ LQ I P D D L+AME AL LEK N+ LL Sbjct: 90 EEREHAEKLMEYQNKRGGKVKLQSIVMPLSDFDHADKGDALHAMELALSLEKLTNEKLLN 149 Query: 118 LHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDK---H 174 LH +AT D L DF+ET YL EQV+AIK + ++V LR++G G + FD+ H Sbjct: 150 LHSVATKNGDVQLADFVETEYLGEQVEAIKRISEYVAQLRRVG---KGHGVWHFDQMLLH 206 Query: 175 TLGDS 179 GD+ Sbjct: 207 EGGDA 211 >3VNX-A nrPDB Length = 204 Score = 138 bits (347), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 81/183 (44%), Positives = 105/183 (57%), Gaps = 8/183 (4%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 + S R YH + EAAIN QIN+E SYVY ++ YF RD+V L FAK+F S Sbjct: 25 APVTDSYARVEYHIECEAAINEQINIEYTISYVYHALHSYFARDNVGLPGFAKFFKEASD 84 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDC----DDWESGLNAMECALHLEKNVNQSLLE 117 EEREHA LM Q +RGGR+ L+ + P+ DD L AME AL LEK Q L Sbjct: 85 EEREHAHMLMDYQTKRGGRVELKPLAAPEMEFANDDKGEALYAMELALSLEKLNFQKLQA 144 Query: 118 LHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 L +A D LCDF+E L+EQV A+KE +V+ LR++G G+ YL D+ LG Sbjct: 145 LQAIADKHKDAALCDFVEGGLLSEQVDAVKEHAVYVSQLRRVG---KGVGVYLLDQE-LG 200 Query: 178 DSD 180 + + Sbjct: 201 EEE 203 >5LS9-A nrPDB Length = 173 Score = 106 bits (264), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 63/147 (42%), Positives = 88/147 (59%), Gaps = 4/147 (2%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+NRQIN E+Y++Y+YLSM+ YFD + LK F+ + Q EE HA K+ ++RGG Sbjct: 11 ALNRQINAEIYSAYLYLSMASYFD--SIGLKGFSNWMRVQWQEELCHAMKMFDFVSERGG 68 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 RIFLQDIKKPD +WES L A E E NV + + EL ++A + D +F++ Y+ Sbjct: 69 RIFLQDIKKPDS-EWESPLAAFEHVYEHEVNVTKRIHELVEMAMQEKDFATYNFLQ-WYV 126 Query: 140 NEQVKAIKELGDHVTNLRKMGAPESGL 166 EQV+ D V LR +G + L Sbjct: 127 AEQVEEEASALDIVEKLRLIGEDKRAL 153 >1Z6O-M nrPDB Length = 191 Score = 96.7 bits (239), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 57/171 (33%), Positives = 90/171 (52%), Gaps = 7/171 (4%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 H+ ++ +QI +E+ AS YL+M +F +D V FA+ F + EEREHA KL++ Sbjct: 18 HRSCRNSMRQQIQMEVGASLQYLAMGAHFSKDVVNRPGFAQLFFDAASEEREHAMKLIEY 77 Query: 74 QNQRGGRI----FLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK---N 126 RG L ++ P W+ G+ A+E AL +E +V +S+ + K D N Sbjct: 78 LLMRGELTNDVSSLLQVRPPTRSSWKGGVEALEHALSMESDVTKSIRNVIKACEDDSEFN 137 Query: 127 DPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 D HL D++ +L EQ K ++L + L+K+ L E++FDK LG Sbjct: 138 DYHLVDYLTGDFLEEQYKGQRDLAGKASTLKKLMDRHEALGEFIFDKKLLG 188 >1S3Q-A nrPDB Length = 173 Score = 89.0 bits (219), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 53/141 (37%), Positives = 82/141 (58%), Gaps = 4/141 (2%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+NRQIN E+Y++Y+YLSM+ YF D + LK F+ + Q EE HA K+ ++RGG Sbjct: 11 ALNRQINAEIYSAYLYLSMASYF--DSIGLKGFSNWMRVQWQEELMHAMKMFDFVSERGG 68 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 R+ L +++P +W+S L A E E NV + + EL ++A + D +F++ Y+ Sbjct: 69 RVKLYAVEEPPS-EWDSPLAAFEHVYEHEVNVTKRIHELVEMAMQEKDFATYNFLQ-WYV 126 Query: 140 NEQVKAIKELGDHVTNLRKMG 160 EQV+ D V LR +G Sbjct: 127 AEQVEEEASALDIVEKLRLIG 147 >1Z4A-A nrPDB Length = 164 Score = 84.0 bits (206), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 48/125 (38%), Positives = 77/125 (61%), Gaps = 4/125 (3%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+N Q+N E+Y+SY+YLSM+ YFD + K FA + Q+ EE HA K + +RGG Sbjct: 11 ALNEQLNREIYSSYLYLSMATYFDAE--GFKGFAHWMKKQAQEELTHAMKFYEYIYERGG 68 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 R+ L+ I+KP +W +A E AL E+ V QS+ + +LA+++ D F++ ++ Sbjct: 69 RVELEAIEKPPS-NWNGIKDAFEAALKHEEFVTQSIYNILELASEEKDHATVSFLKW-FV 126 Query: 140 NEQVK 144 +EQV+ Sbjct: 127 DEQVE 131 >2JD8-0 nrPDB Length = 174 Score = 83.2 bits (204), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 51/137 (37%), Positives = 82/137 (59%), Gaps = 7/137 (5%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+N Q+N ELY++Y+Y +M+ YF +D+ L+ FA + Q+ EE HA + R G Sbjct: 9 ALNDQLNRELYSAYLYFAMAAYF--EDLGLEGFANWMKAQAEEEIGHALRFYNYIYDRNG 66 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 R+ L +I KP +WES L A E A EK +++S+ EL LA ++ D F+E ++ Sbjct: 67 RVELDEIPKP-PKEWESPLKAFEAAYEHEKFISKSIYELAALAEEEKDYSTRAFLE-WFI 124 Query: 140 NEQVK---AIKELGDHV 153 NEQV+ ++K++ D + Sbjct: 125 NEQVEEEASVKKILDKL 141 >4ZL6-B nrPDB Length = 169 Score = 70.5 bits (171), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 3/122 (2%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 NRQ+ E AS VYLS S +FD++D + A Y L S EEREH + N+R Sbjct: 9 FNRQVTQEFTASQVYLSASIWFDQND--WEGMAAYMLAHSAEEREHGLGFVDFANKRNIP 66 Query: 81 IFLQDIKKP-DCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 I LQ + P C +W S + + L LE+ +SLL L + A+ +D + F+ +L Sbjct: 67 IELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHL 126 Query: 140 NE 141 + Sbjct: 127 QQ 128 >1KRQ-A nrPDB Length = 167 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 14/146 (9%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N QIN E+YA+ +YLSMS + + +L + + EE +HA+KL+ N+ Sbjct: 10 LNEQINKEMYAANLYLSMSSWCYEN--SLDGAGAFLFAHASEESDHAKKLITYLNETDSH 67 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 + LQ++K+P+ +++S L+ E E+ + +S+ L + D +F++ Y++ Sbjct: 68 VELQEVKQPE-QNFKSLLDVFEKTYEHEQFITKSINTLVEHMLTHKDYSTFNFLQW-YVS 125 Query: 141 EQ----------VKAIKELGDHVTNL 156 EQ V IK +G+H L Sbjct: 126 EQHEEEALFRGIVDKIKLIGEHGNGL 151 >4CMY-A nrPDB Length = 203 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 33/122 (27%), Positives = 61/122 (50%), Gaps = 4/122 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N Q+N E ++++YL MS + +L + A +F + EE+ H KL N+ G Sbjct: 10 LNHQVNFEAASAHLYLQMSAWLLTQ--SLDSTAAFFRAHAEEEKAHMMKLFDYINETGSL 67 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 + ++ P +W+S + +E A + E + QS+ +L A + D F++ Y+ Sbjct: 68 ALIGEVATP-APEWKSHIELLEAAYNHELAITQSINDLVDTALREKDYSTFQFLQW-YVA 125 Query: 141 EQ 142 EQ Sbjct: 126 EQ 127 >3OJ5-A nrPDB Length = 189 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 70/145 (48%), Gaps = 8/145 (5%) Query: 19 AAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRG 78 A + QI+ E A+ Y++++ YFD +D L AK+F Q+ EER HA L++ R Sbjct: 13 ALMQEQIHNEFTAAQQYVAIAVYFDSED--LPQLAKHFYSQAVEERNHAMMLVQHLLDRD 70 Query: 79 GRIFLQDIKKPDC--DDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIET 136 R+ +I D + ++ A+ AL E+ V + L +A D+ D L + Sbjct: 71 LRV---EIPGVDTVRNQFDRPREALALALDQERTVTDQVGRLTAVARDEGD-FLGEQFMQ 126 Query: 137 HYLNEQVKAIKELGDHVTNLRKMGA 161 +L EQ++ + + V + GA Sbjct: 127 WFLQEQIEEVALMATLVRVADRAGA 151 >1Z6O-A nrPDB Length = 212 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 13/161 (8%) Query: 27 LELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFL--Q 84 L L SY YL + YF+ F+K F S E ++K +RG ++ Sbjct: 47 LHLERSYDYLLSAAYFNNYQTNRAGFSKLFKKLSDEAWSKTIDIIKHVTKRGDKMNFDQH 106 Query: 85 DIKKPDCDDWESG---LNAMECALHLEKNVNQSLLELHKLATDKN----DPHLCDFIETH 137 K + ++ + L A+ AL +K + + +H+ AT + DP + ++E Sbjct: 107 STMKTERKNYTAENHELEALAKALDTQKELAERAFYIHREATRNSQHLHDPEIAQYLEEE 166 Query: 138 YLNEQVKAIKELGDHVTNLRKMGAPESG----LAEYLFDKH 174 ++ + + I+ L H ++L+K +G LA Y+FD++ Sbjct: 167 FIEDHAEKIRTLAGHTSDLKKFITANNGHDLSLALYVFDEY 207 >3QZ3-A nrPDB Length = 184 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N QINLE ++S +YL MS + +D A++ + EE +H ++L ++ G Sbjct: 19 LNEQINLEFFSSNLYLQMSAW--CEDKGFDGAAEFLRAHAVEEMQHMQRLFTYVSETGAL 76 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 L I P D G E H E+ + Q + +L +A D +F++ Y+ Sbjct: 77 PILGAIAAPRHDFASLGEVFRETYQH-EQKITQQINKLAHVAFTSQDYSTFNFLQW-YVA 134 Query: 141 EQVKAIKELGDHVTNLRKMGAPESGLAEYLFDK 173 EQ + K + L +G E G A + DK Sbjct: 135 EQHEEEKLFKGILDKLELVG--EDGKALFFIDK 165 >5C6F-A nrPDB Length = 173 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 42/160 (26%), Positives = 74/160 (46%), Gaps = 12/160 (7%) Query: 21 INRQINLELYASYVYLSMS---YYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQR 77 +N Q+N E+ +S +Y+SMS Y D L + + EE EHA+KL+ N+ Sbjct: 16 LNEQVNKEMNSSNLYMSMSSWCYTHSLDGAGL-----FLFDHAAEEYEHAKKLIIFLNEN 70 Query: 78 GGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETH 137 + L I P+ +E + A LE+++++S+ + A D +F++ Sbjct: 71 NVPVQLTSISAPE-HKFEGLTQIFQKAYELEQHISESINNIVDHAIKSKDHATFNFLQW- 128 Query: 138 YLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 Y+ EQ + D + + +G GL YL D++ G Sbjct: 129 YVAEQHEEEVLFKDILDKIELIGNENHGL--YLADQYVKG 166 >5U1A-A nrPDB Length = 182 Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust. Identities = 41/170 (24%), Positives = 75/170 (44%), Gaps = 17/170 (10%) Query: 21 INRQINLELYASYVYLSMS---YYFDR----------DDVALKNFAKYFLHQSHEEREHA 67 +N Q+N E+ +S +Y+SMS Y R +L + + EE EHA Sbjct: 10 LNEQVNKEMNSSNLYMSMSSWCYTGSRQGSLSGGNVSSSYSLDGCGTFLFDHAAEEYEHA 69 Query: 68 EKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKND 127 +KL+ N+ + L I P+ +E + A E+++++S+ + A D Sbjct: 70 KKLIVFLNENNVPVQLTSISAPE-HKFEGLTQIFQKAYEHEQHISESINNIVDHAIKSKD 128 Query: 128 PHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 +F++ Y++EQ + D + + +G GL YL D++ G Sbjct: 129 HATFNFLQW-YVSEQHEEEVLFKDILDKIELIGNENHGL--YLADQYVKG 175 >4ZTT-A nrPDB Length = 166 Score = 34.7 bits (78), Expect = 0.024, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 10/155 (6%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N Q+NLELYAS +Y MS + + A + + EE H ++L G Sbjct: 11 LNEQMNLELYASLLYQQMSAWCSYH--TFEGAAAFLRRHAQEEMTHMQRLFDYLTDTGNL 68 Query: 81 IFLQDIKKPDCDDWESGLNAM--ECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHY 138 + ++ P + S L+ + E H E+ + Q + EL A D +F++ Y Sbjct: 69 PRINTVESPFAE--YSSLDELFQETYKH-EQLITQKINELAHAAMTNQDYPTFNFLQW-Y 124 Query: 139 LNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDK 173 ++EQ + K + L G GL Y DK Sbjct: 125 VSEQHEEEKLFKSIIDKLSLAGKSGEGL--YFIDK 157 >5TFQ-A nrPDB Length = 280 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 8/73 (10%) Query: 108 EKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLA 167 ++++ SL EL K K+D + CD L E V I ++ ++V + +G + LA Sbjct: 94 DQDITISLGELLKYTISKSDNNTCDI-----LIEYVGGIDQVNEYV---KSLGIKDCNLA 145 Query: 168 EYLFDKHTLGDSD 180 HT GD+D Sbjct: 146 ATETLMHTSGDTD 158 >4LJY-A nrPDB Length = 493 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 98 LNA--MECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LNA + CA+H K + L+ L K +KN LC + + LN Sbjct: 341 LNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLN 385 >3FMC-A nrPDB Length = 368 Score = 27.7 bits (60), Expect = 3.1, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 17/27 (62%) Query: 144 KAIKELGDHVTNLRKMGAPESGLAEYL 170 K +K G + N RK AP++G+ EYL Sbjct: 278 KPMKRYGCFLKNYRKFHAPKAGMVEYL 304 >4X4R-A nrPDB Length = 457 Score = 27.3 bits (59), Expect = 3.7, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 17/38 (44%) Query: 56 FLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDD 93 F H E+L K+ +RG +F +KPD D Sbjct: 253 FFKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVD 290 >2DTU-A nrPDB Length = 896 Score = 26.9 bits (58), Expect = 4.5, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 6/53 (11%) Query: 38 MSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPD 90 M YY DRD V K F ++ +EH K L QR G I + + P+ Sbjct: 454 MMYYKDRDGVVPTEITKVF----NQRKEH--KGYMLAAQRNGEIIKEALHNPN 500 >4E6K-A nrPDB Length = 158 Score = 26.2 bits (56), Expect = 9.4, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 67/139 (48%), Gaps = 13/139 (9%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N+ + EL A Y S ++ D LK + H+S +E +HA+KL++ G Sbjct: 11 LNKILGNELIAINQYFLHSRMWN--DWGLKRLGAHEYHESIDEMKHADKLIERILFLEGL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLE----KNVNQSLLELHKLATDKNDPHLCDFIET 136 LQD+ K E+ ++C L+LE K++ ++++ ++ + L D +E+ Sbjct: 69 PNLQDLGKLLIG--ENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILES 126 Query: 137 H-----YLNEQVKAIKELG 150 YL Q+ I+++G Sbjct: 127 EEEHIDYLETQLGLIQKVG 145 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5OBB-A nrPDB 271 2e-73 3AJP-A nrPDB 271 2e-73 3WNW-A nrPDB 268 1e-72 5JKM-A nrPDB 264 2e-71 5GN8-A nrPDB 259 5e-70 1R03-A nrPDB 253 4e-68 1BG7-A nrPDB 251 1e-67 6I36-A nrPDB 243 4e-65 1RCD-A nrPDB 233 4e-62 5WPN-A nrPDB 229 4e-61 6A4U-A nrPDB 228 8e-61 4V6B-AA nrPDB 224 2e-59 2V2I-A nrPDB 218 1e-57 5GN8-B nrPDB 215 1e-56 1H96-A nrPDB 214 2e-56 3A68-A nrPDB 195 1e-50 3VNX-A nrPDB 191 2e-49 1Z6O-M nrPDB 178 1e-45 5LS9-A nrPDB 169 7e-43 1S3Q-A nrPDB 162 8e-41 2JD8-0 nrPDB 152 1e-37 1KRQ-A nrPDB 150 3e-37 1Z4A-A nrPDB 149 1e-36 5C6F-A nrPDB 148 1e-36 3QZ3-A nrPDB 144 3e-35 4ZL6-B nrPDB 140 5e-34 4CMY-A nrPDB 133 4e-32 3OJ5-A nrPDB 125 9e-30 1Z6O-A nrPDB 123 5e-29 Sequences not found previously or not previously below threshold: 5U1A-A nrPDB 149 7e-37 4ZTT-A nrPDB 123 6e-29 5OUZ-A nrPDB 76 7e-15 5ZUR-A nrPDB 48 2e-06 4E6K-A nrPDB 47 6e-06 3BKN-A nrPDB 46 7e-06 5XX9-A nrPDB 45 1e-05 2FKZ-A nrPDB 45 2e-05 3UOF-A nrPDB 44 4e-05 3FVB-A nrPDB 41 4e-04 4AM2-A nrPDB 40 6e-04 1JGC-A nrPDB 35 0.014 3R2L-A nrPDB 35 0.015 3GVY-A nrPDB 35 0.022 4CVS-A nrPDB 34 0.048 1JYB-A nrPDB 33 0.060 5TX1-M nrPDB 31 0.37 1K1Y-A nrPDB 28 1.7 3FLO-A nrPDB 28 1.9 4DRY-A nrPDB 28 2.7 3LPM-A nrPDB 28 3.2 2VA1-A nrPDB 27 3.9 2E0Z-A nrPDB 27 5.3 4LNS-A nrPDB 27 6.2 1NDS-A nrPDB 27 6.6 1X18-E nrPDB 27 6.8 5UI5-I nrPDB 26 8.0 >5OBB-A nrPDB Length = 197 Score = 271 bits (692), Expect = 2e-73, Method: Composition-based stats. Identities = 168/179 (93%), Positives = 175/179 (97%) Query: 1 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 MTTAS SQVRQNYHQD+EAAINRQINLELYASYVYLSMS YFDRDDVALKNFAKYFLHQS Sbjct: 1 MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQS 60 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 HEEREHAEKLMKLQNQRGGRIFLQDIKKPD DDWESGLNAMECALHLEK+VNQSLLELHK Sbjct: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHK 120 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 LATDKNDPHLCDFIET+YL+EQVK+IKELGDHVTNLRKMGAPE+G+AEYLFDKHTLG S Sbjct: 121 LATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGGS 179 >3AJP-A nrPDB Length = 182 Score = 271 bits (692), Expect = 2e-73, Method: Composition-based stats. Identities = 181/182 (99%), Positives = 181/182 (99%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH Sbjct: 1 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL Sbjct: 61 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 ATDKNDPHLCDFIETHYLN QVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN Sbjct: 121 ATDKNDPHLCDFIETHYLNAQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 180 Query: 182 ES 183 ES Sbjct: 181 ES 182 >3WNW-A nrPDB Length = 212 Score = 268 bits (684), Expect = 1e-72, Method: Composition-based stats. Identities = 168/181 (92%), Positives = 175/181 (96%) Query: 1 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 MTTAS SQVRQNYHQD+EAAINRQINLELYASYVYLSMS YFDRDDVALKNFAKYFLHQS Sbjct: 18 MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQS 77 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 HEEREHAEKLMKLQNQRGGRIFLQDIKKPD DDWESGLNAMECALHLEK+VNQSLLELHK Sbjct: 78 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHK 137 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD 180 LATDKNDPHLCDFIET+YL+EQVK+IKELGDHVTNLRKMGAPE+G+AEYLFDKHTLG D Sbjct: 138 LATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGD 197 Query: 181 N 181 Sbjct: 198 E 198 >5JKM-A nrPDB Length = 183 Score = 264 bits (674), Expect = 2e-71, Method: Composition-based stats. Identities = 173/183 (94%), Positives = 174/183 (95%) Query: 1 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 MTTASTSQVRQNYHQDSE AINRQI LELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS Sbjct: 1 MTTASTSQVRQNYHQDSEKAINRQIRLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 60 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 HEEREHAEKLMKLQNQRGGRIFLQDI+KPD DDWESGL AME AL LEK VNQSLLELHK Sbjct: 61 HEEREHAEKLMKLQNQRGGRIFLQDIQKPDKDDWESGLRAMEKALKLEKKVNQSLLELHK 120 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD 180 LAT KNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAP SGLAEYLFDKHTLGDSD Sbjct: 121 LATKKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPRSGLAEYLFDKHTLGDSD 180 Query: 181 NES 183 NES Sbjct: 181 NES 183 >5GN8-A nrPDB Length = 176 Score = 259 bits (662), Expect = 5e-70, Method: Composition-based stats. Identities = 176/182 (96%), Positives = 176/182 (96%), Gaps = 6/182 (3%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH Sbjct: 1 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL Sbjct: 61 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 ATDKNDPHLCDFIETHYL IKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN Sbjct: 121 ATDKNDPHLCDFIETHYL------IKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 174 Query: 182 ES 183 ES Sbjct: 175 ES 176 >1R03-A nrPDB Length = 182 Score = 253 bits (646), Expect = 4e-68, Method: Composition-based stats. Identities = 145/182 (79%), Positives = 163/182 (89%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 A S+VRQN+H DSEAAINRQINLELYASYVYLSM+YYF RDDVAL NF++YFLHQS Sbjct: 1 PAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSR 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EE EHAEKLM+LQNQRGGRI LQDIKKP+ DDWESGL+AMECAL LEKNVNQSLLELH L Sbjct: 61 EETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHAL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 A+DK DPHLCDF+ET+YLNEQVK+IKELGDHV NL KMGAP++GLAEYLFD HTLG+ + Sbjct: 121 ASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTHTLGNENK 180 Query: 182 ES 183 ++ Sbjct: 181 QN 182 >1BG7-A nrPDB Length = 176 Score = 251 bits (641), Expect = 1e-67, Method: Composition-based stats. Identities = 118/174 (67%), Positives = 150/174 (86%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 SQVRQN+H+D EAAINR +N+ELYASY YLSM++YFDRDD+AL N AK+F QSHEERE Sbjct: 2 DSQVRQNFHRDCEAAINRMVNMELYASYTYLSMAFYFDRDDIALHNVAKFFKEQSHEERE 61 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 HAEKLMK QN+RGGRI LQD++KP+ D+W + L AM+ AL LEK VNQ+LL+LHK+ +DK Sbjct: 62 HAEKLMKDQNKRGGRIVLQDVQKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKVGSDK 121 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 DPHLCDF+ET Y EQVK+IK+LGD++TNL+++G P++G+ EYLFDKHT+G+S Sbjct: 122 VDPHLCDFLETEYPEEQVKSIKQLGDYITNLKRLGLPQNGMGEYLFDKHTMGES 175 >6I36-A nrPDB Length = 176 Score = 243 bits (620), Expect = 4e-65, Method: Composition-based stats. Identities = 117/173 (67%), Positives = 142/173 (82%) Query: 7 SQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREH 66 SQVRQNYH D EAA+NR +NLELYASY Y SM +FDRDDVAL N A++F SHEEREH Sbjct: 3 SQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEHSHEEREH 62 Query: 67 AEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKN 126 AEK MK QN+RGGR+ LQDIKKP+ D+W + L AM+ AL LEK VNQ+LL+LHKLATDK Sbjct: 63 AEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDKV 122 Query: 127 DPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDS 179 DPHLCDF+E+ YL EQVK IK +GD +TNL+++G PE+G+ EYLFDKH++ +S Sbjct: 123 DPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKES 175 >1RCD-A nrPDB Length = 173 Score = 233 bits (594), Expect = 4e-62, Method: Composition-based stats. Identities = 106/171 (61%), Positives = 145/171 (84%) Query: 7 SQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREH 66 SQVRQN+HQD EA +NR +NL+ ++SYVYLSM+ YF+RDDVAL NFAK+F +S EE+EH Sbjct: 3 SQVRQNFHQDCEAGLNRTVNLKFHSSYVYLSMASYFNRDDVALSNFAKFFRERSEEEKEH 62 Query: 67 AEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKN 126 AEKL++ QNQRGGR+FLQ ++KP+ DDW +GL A++ AL L+K+VNQ+LL+LH +A DK+ Sbjct: 63 AEKLIEYQNQRGGRVFLQSVEKPERDDWANGLEALQTALKLQKSVNQALLDLHAVAADKS 122 Query: 127 DPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 DPH+ DF+E+ YL+E V+ IK+LGDH+T+L+K+ + G+AEYLF+KHTLG Sbjct: 123 DPHMTDFLESPYLSESVETIKKLGDHITSLKKLWSSHPGMAEYLFNKHTLG 173 >5WPN-A nrPDB Length = 171 Score = 229 bits (585), Expect = 4e-61, Method: Composition-based stats. Identities = 114/174 (65%), Positives = 140/174 (80%), Gaps = 3/174 (1%) Query: 5 STSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEER 64 + +Q RQNY D EA IN+QINLELYASYVY SM+++FDRDD+ALK F K+F HQS EER Sbjct: 1 AQTQPRQNYASDVEAGINKQINLELYASYVYQSMAWFFDRDDIALKGFHKFFKHQSEEER 60 Query: 65 EHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATD 124 EHAEKLM+ QN+RGGRI LQDI+KP+ D+W +GL AM+ AL LEKNVNQSLL+LHK+ Sbjct: 61 EHAEKLMQYQNKRGGRIVLQDIQKPERDEWGTGLEAMQVALALEKNVNQSLLDLHKVGAG 120 Query: 125 KNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGD 178 +D HLCDF+E HYL EQVK+IKEL D+VTNL+++G GL EY+FDK +L Sbjct: 121 HDDAHLCDFLEEHYLEEQVKSIKELSDYVTNLKRVG---PGLGEYMFDKESLSS 171 >6A4U-A nrPDB Length = 169 Score = 228 bits (582), Expect = 8e-61, Method: Composition-based stats. Identities = 104/170 (61%), Positives = 127/170 (74%), Gaps = 2/170 (1%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 SQVRQNYH+D EA+IN+QIN+ELYASYVYLSM+YYF+RDDVAL FAK+F S EERE Sbjct: 1 ASQVRQNYHEDCEASINKQINMELYASYVYLSMAYYFERDDVALPGFAKFFKESSDEERE 60 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 HA+ MK QN+RGGRI LQ I P +W +GL A++ AL LEK VNQSLLELH A+ Sbjct: 61 HAQTFMKYQNKRGGRIVLQQIAAPSMREWGTGLEALQAALDLEKQVNQSLLELHSTASGN 120 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHT 175 NDPHL +E YL EQV +IK++GD +T L++ G +GL EY+FDK Sbjct: 121 NDPHLTKLLEDEYLEEQVDSIKKIGDMITKLKRAGP--TGLGEYMFDKEL 168 >4V6B-AA nrPDB Length = 192 Score = 224 bits (570), Expect = 2e-59, Method: Composition-based stats. Identities = 96/176 (54%), Positives = 131/176 (74%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 +SQ+RQNY D EAA+N +NL L ASY YLS+ +YFDRDDVAL+ + +F + E+RE Sbjct: 3 SSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKRE 62 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 E+L+K+QNQRGGR QDIKKP D+W +AM+ A+ LEK +NQ+LL+LH L + + Sbjct: 63 GYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSAR 122 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 DPHLCDF+ETH+L+E+VK IK++GDH+TNL ++G PE+GL EYL K +L + Sbjct: 123 TDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLSSKGSLSSTTK 178 >2V2I-A nrPDB Length = 175 Score = 218 bits (556), Expect = 1e-57, Method: Composition-based stats. Identities = 91/173 (52%), Positives = 134/173 (77%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 +SQ+RQNY + EAA+NR +NL L ASY YLS+ +YFDRDDVAL+ +F + E+RE Sbjct: 2 SSQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALEGVCHFFRELAEEKRE 61 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 AE+L+K+QNQRGGR QD++KP D+W + +AM+ A+ LEK++NQ+LL+LH L + + Sbjct: 62 GAERLLKMQNQRGGRALFQDLQKPSQDEWGTTPDAMKAAIVLEKSLNQALLDLHALGSAQ 121 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGD 178 DPHLCDF+E+H+L+E+VK IK++GDH+TN++++ ++GL EYLF++ TL Sbjct: 122 ADPHLCDFLESHFLDEEVKLIKKMGDHLTNIQRLVGSQAGLGEYLFERLTLKH 174 >5GN8-B nrPDB Length = 146 Score = 215 bits (547), Expect = 1e-56, Method: Composition-based stats. Identities = 146/152 (96%), Positives = 146/152 (96%), Gaps = 6/152 (3%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH Sbjct: 1 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 60 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 121 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL Sbjct: 61 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKL 120 Query: 122 ATDKNDPHLCDFIETHYLNEQVKAIKELGDHV 153 ATDKNDPHLCDFIETHYL IKELGDHV Sbjct: 121 ATDKNDPHLCDFIETHYL------IKELGDHV 146 >1H96-A nrPDB Length = 182 Score = 214 bits (545), Expect = 2e-56, Method: Composition-based stats. Identities = 94/181 (51%), Positives = 131/181 (72%), Gaps = 8/181 (4%) Query: 6 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEERE 65 TSQ+RQNY + EAA+NR +NL L ASY YLS+ ++FDRDDVAL+ +F + E+RE Sbjct: 1 TSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKRE 60 Query: 66 HAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK 125 AE+L++ QN RGGR QD++KP D+W AME AL +EKN+NQ+LL+LH L + + Sbjct: 61 GAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSAR 120 Query: 126 NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKM--------GAPESGLAEYLFDKHTLG 177 DPHLCDF+E+HYL+++VK IK++G+H+TNLR++ GAP+ L EYLF++ TL Sbjct: 121 ADPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFERLTLK 180 Query: 178 D 178 Sbjct: 181 H 181 >3A68-A nrPDB Length = 212 Score = 195 bits (495), Expect = 1e-50, Method: Composition-based stats. Identities = 89/182 (48%), Positives = 114/182 (62%), Gaps = 7/182 (3%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 T S RQ Y +SE+A+N QIN+E SYVY +M YFDRD+VAL+ AK+F S Sbjct: 30 TVPQASLARQKYVDESESAVNEQINVEYNVSYVYHAMFAYFDRDNVALRGLAKFFKESSE 89 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKP----DCDDWESGLNAMECALHLEKNVNQSLLE 117 EEREHAEKLM+ QN+RGG++ LQ I P D D L+AME AL LEK N+ LL Sbjct: 90 EEREHAEKLMEYQNKRGGKVKLQSIVMPLSDFDHADKGDALHAMELALSLEKLTNEKLLN 149 Query: 118 LHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 LH +AT D L DF+ET YL EQV+AIK + ++V LR++G G + FD+ L Sbjct: 150 LHSVATKNGDVQLADFVETEYLGEQVEAIKRISEYVAQLRRVG---KGHGVWHFDQMLLH 206 Query: 178 DS 179 + Sbjct: 207 EG 208 >3VNX-A nrPDB Length = 204 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 81/183 (44%), Positives = 105/183 (57%), Gaps = 8/183 (4%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 + S R YH + EAAIN QIN+E SYVY ++ YF RD+V L FAK+F S Sbjct: 25 APVTDSYARVEYHIECEAAINEQINIEYTISYVYHALHSYFARDNVGLPGFAKFFKEASD 84 Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDC----DDWESGLNAMECALHLEKNVNQSLLE 117 EEREHA LM Q +RGGR+ L+ + P+ DD L AME AL LEK Q L Sbjct: 85 EEREHAHMLMDYQTKRGGRVELKPLAAPEMEFANDDKGEALYAMELALSLEKLNFQKLQA 144 Query: 118 LHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 L +A D LCDF+E L+EQV A+KE +V+ LR++G G+ YL D+ LG Sbjct: 145 LQAIADKHKDAALCDFVEGGLLSEQVDAVKEHAVYVSQLRRVG---KGVGVYLLDQE-LG 200 Query: 178 DSD 180 + + Sbjct: 201 EEE 203 >1Z6O-M nrPDB Length = 191 Score = 178 bits (452), Expect = 1e-45, Method: Composition-based stats. Identities = 57/171 (33%), Positives = 90/171 (52%), Gaps = 7/171 (4%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 H+ ++ +QI +E+ AS YL+M +F +D V FA+ F + EEREHA KL++ Sbjct: 18 HRSCRNSMRQQIQMEVGASLQYLAMGAHFSKDVVNRPGFAQLFFDAASEEREHAMKLIEY 77 Query: 74 QNQRGGRIF----LQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDK---N 126 RG L ++ P W+ G+ A+E AL +E +V +S+ + K D N Sbjct: 78 LLMRGELTNDVSSLLQVRPPTRSSWKGGVEALEHALSMESDVTKSIRNVIKACEDDSEFN 137 Query: 127 DPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 D HL D++ +L EQ K ++L + L+K+ L E++FDK LG Sbjct: 138 DYHLVDYLTGDFLEEQYKGQRDLAGKASTLKKLMDRHEALGEFIFDKKLLG 188 >5LS9-A nrPDB Length = 173 Score = 169 bits (428), Expect = 7e-43, Method: Composition-based stats. Identities = 63/147 (42%), Positives = 88/147 (59%), Gaps = 4/147 (2%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+NRQIN E+Y++Y+YLSM+ YF D + LK F+ + Q EE HA K+ ++RGG Sbjct: 11 ALNRQINAEIYSAYLYLSMASYF--DSIGLKGFSNWMRVQWQEELCHAMKMFDFVSERGG 68 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 RIFLQDIKKPD +WES L A E E NV + + EL ++A + D +F++ Y+ Sbjct: 69 RIFLQDIKKPDS-EWESPLAAFEHVYEHEVNVTKRIHELVEMAMQEKDFATYNFLQW-YV 126 Query: 140 NEQVKAIKELGDHVTNLRKMGAPESGL 166 EQV+ D V LR +G + L Sbjct: 127 AEQVEEEASALDIVEKLRLIGEDKRAL 153 >1S3Q-A nrPDB Length = 173 Score = 162 bits (410), Expect = 8e-41, Method: Composition-based stats. Identities = 54/147 (36%), Positives = 84/147 (57%), Gaps = 4/147 (2%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+NRQIN E+Y++Y+YLSM+ YF D + LK F+ + Q EE HA K+ ++RGG Sbjct: 11 ALNRQINAEIYSAYLYLSMASYF--DSIGLKGFSNWMRVQWQEELMHAMKMFDFVSERGG 68 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 R+ L +++P +W+S L A E E NV + + EL ++A + D +F++ Y+ Sbjct: 69 RVKLYAVEEPPS-EWDSPLAAFEHVYEHEVNVTKRIHELVEMAMQEKDFATYNFLQW-YV 126 Query: 140 NEQVKAIKELGDHVTNLRKMGAPESGL 166 EQV+ D V LR +G + L Sbjct: 127 AEQVEEEASALDIVEKLRLIGEDKRAL 153 >2JD8-0 nrPDB Length = 174 Score = 152 bits (383), Expect = 1e-37, Method: Composition-based stats. Identities = 53/156 (33%), Positives = 84/156 (53%), Gaps = 6/156 (3%) Query: 20 AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 A+N Q+N ELY++Y+Y +M+ YF +D+ L+ FA + Q+ EE HA + R G Sbjct: 9 ALNDQLNRELYSAYLYFAMAAYF--EDLGLEGFANWMKAQAEEEIGHALRFYNYIYDRNG 66 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 R+ L +I KP +WES L A E A EK +++S+ EL LA ++ D F+E ++ Sbjct: 67 RVELDEIPKPP-KEWESPLKAFEAAYEHEKFISKSIYELAALAEEEKDYSTRAFLEW-FI 124 Query: 140 NEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHT 175 NEQV+ + + L+ L ++ DK Sbjct: 125 NEQVEEEASVKKILDKLKFAKDSPQIL--FMLDKEL 158 >1KRQ-A nrPDB Length = 167 Score = 150 bits (379), Expect = 3e-37, Method: Composition-based stats. Identities = 42/163 (25%), Positives = 82/163 (50%), Gaps = 6/163 (3%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 ++ +N QIN E+YA+ +YLSMS + + +L + + EE +HA+KL+ Sbjct: 3 SKEVVKLLNEQINKEMYAANLYLSMSSWCYEN--SLDGAGAFLFAHASEESDHAKKLITY 60 Query: 74 QNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDF 133 N+ + LQ++K+P+ +++S L+ E E+ + +S+ L + D +F Sbjct: 61 LNETDSHVELQEVKQPEQ-NFKSLLDVFEKTYEHEQFITKSINTLVEHMLTHKDYSTFNF 119 Query: 134 IETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTL 176 ++ Y++EQ + V ++ +G E G YL D++ Sbjct: 120 LQW-YVSEQHEEEALFRGIVDKIKLIG--EHGNGLYLADQYIK 159 >5U1A-A nrPDB Length = 182 Score = 149 bits (376), Expect = 7e-37, Method: Composition-based stats. Identities = 40/177 (22%), Positives = 76/177 (42%), Gaps = 17/177 (9%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFD-------------RDDVALKNFAKYFLHQS 60 +D +N Q+N E+ +S +Y+SMS + +L + + Sbjct: 3 SKDIIKLLNEQVNKEMNSSNLYMSMSSWCYTGSRQGSLSGGNVSSSYSLDGCGTFLFDHA 62 Query: 61 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 120 EE EHA+KL+ N+ + L I P+ +E + A E+++++S+ + Sbjct: 63 AEEYEHAKKLIVFLNENNVPVQLTSISAPEHK-FEGLTQIFQKAYEHEQHISESINNIVD 121 Query: 121 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 A D +F++ Y++EQ + D + + +G GL YL D++ G Sbjct: 122 HAIKSKDHATFNFLQW-YVSEQHEEEVLFKDILDKIELIGNENHGL--YLADQYVKG 175 >1Z4A-A nrPDB Length = 164 Score = 149 bits (375), Expect = 1e-36, Method: Composition-based stats. Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 4/146 (2%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 + A+N Q+N E+Y+SY+YLSM+ YFD + K FA + Q+ EE HA K + Sbjct: 5 SEKVRKALNEQLNREIYSSYLYLSMATYFDAE--GFKGFAHWMKKQAQEELTHAMKFYEY 62 Query: 74 QNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDF 133 +RGGR+ L+ I+KP +W +A E AL E+ V QS+ + +LA+++ D F Sbjct: 63 IYERGGRVELEAIEKPPS-NWNGIKDAFEAALKHEEFVTQSIYNILELASEEKDHATVSF 121 Query: 134 IETHYLNEQVKAIKELGDHVTNLRKM 159 ++ +++EQV+ ++ + + L K Sbjct: 122 LKW-FVDEQVEEEDQVREILDLLEKA 146 >5C6F-A nrPDB Length = 173 Score = 148 bits (373), Expect = 1e-36, Method: Composition-based stats. Identities = 41/164 (25%), Positives = 76/164 (46%), Gaps = 6/164 (3%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 +D +N Q+N E+ +S +Y+SMS + +L + + EE EHA+KL+ Sbjct: 9 SKDIIKLLNEQVNKEMNSSNLYMSMSSWCYTH--SLDGAGLFLFDHAAEEYEHAKKLIIF 66 Query: 74 QNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDF 133 N+ + L I P+ +E + A LE+++++S+ + A D +F Sbjct: 67 LNENNVPVQLTSISAPEHK-FEGLTQIFQKAYELEQHISESINNIVDHAIKSKDHATFNF 125 Query: 134 IETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 177 ++ Y+ EQ + D + + +G GL YL D++ G Sbjct: 126 LQW-YVAEQHEEEVLFKDILDKIELIGNENHGL--YLADQYVKG 166 >3QZ3-A nrPDB Length = 184 Score = 144 bits (362), Expect = 3e-35, Method: Composition-based stats. Identities = 40/153 (26%), Positives = 68/153 (44%), Gaps = 6/153 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N QINLE ++S +YL MS + +D A++ + EE +H ++L ++ G Sbjct: 19 LNEQINLEFFSSNLYLQMSAW--CEDKGFDGAAEFLRAHAVEEMQHMQRLFTYVSETGAL 76 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 L I P D+ S E+ + Q + +L +A D +F++ Y+ Sbjct: 77 PILGAIAAP-RHDFASLGEVFRETYQHEQKITQQINKLAHVAFTSQDYSTFNFLQW-YVA 134 Query: 141 EQVKAIKELGDHVTNLRKMGAPESGLAEYLFDK 173 EQ + K + L +G E G A + DK Sbjct: 135 EQHEEEKLFKGILDKLELVG--EDGKALFFIDK 165 >4ZL6-B nrPDB Length = 169 Score = 140 bits (352), Expect = 5e-34, Method: Composition-based stats. Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 NRQ+ E AS VYLS S +FD++D + A Y L S EEREH + N+R Sbjct: 9 FNRQVTQEFTASQVYLSASIWFDQND--WEGMAAYMLAHSAEEREHGLGFVDFANKRNIP 66 Query: 81 IFLQDIKKP-DCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 I LQ + P C +W S + + L LE+ +SLL L + A+ +D + F+ +L Sbjct: 67 IELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHL 126 Query: 140 NEQVKAIKELGDHVTNL 156 QV ++G + + Sbjct: 127 Q-QVNEEDKIGSILAKV 142 >4CMY-A nrPDB Length = 203 Score = 133 bits (335), Expect = 4e-32, Method: Composition-based stats. Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 5/155 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N Q+N E ++++YL MS + +L + A +F + EE+ H KL N+ G Sbjct: 10 LNHQVNFEAASAHLYLQMSAWLLTQ--SLDSTAAFFRAHAEEEKAHMMKLFDYINETGSL 67 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 + ++ P +W+S + +E A + E + QS+ +L A + D F++ Y+ Sbjct: 68 ALIGEVATP-APEWKSHIELLEAAYNHELAITQSINDLVDTALREKDYSTFQFLQW-YVA 125 Query: 141 EQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHT 175 EQ + + ++ G A + FD+ Sbjct: 126 EQHEEEYLFSSMLHKA-RIINTMDGRALFRFDEEV 159 >3OJ5-A nrPDB Length = 189 Score = 125 bits (315), Expect = 9e-30, Method: Composition-based stats. Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%) Query: 19 AAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRG 78 A + QI+ E A+ Y++++ YFD +D L AK+F Q+ EER HA L++ R Sbjct: 13 ALMQEQIHNEFTAAQQYVAIAVYFDSED--LPQLAKHFYSQAVEERNHAMMLVQHLLDRD 70 Query: 79 GRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHY 138 R+ + + + ++ A+ AL E+ V + L +A D+ D L + + Sbjct: 71 LRVEIPGVDTV-RNQFDRPREALALALDQERTVTDQVGRLTAVARDEGDF-LGEQFMQWF 128 Query: 139 LNEQVKAIKELGDHVTNLRKMGA 161 L EQ++ + + V + GA Sbjct: 129 LQEQIEEVALMATLVRVADRAGA 151 >1Z6O-A nrPDB Length = 212 Score = 123 bits (308), Expect = 5e-29, Method: Composition-based stats. Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 13/175 (7%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 H + + L L SY YL + YF+ F+K F S E ++K Sbjct: 34 HGNVATELQAYAKLHLERSYDYLLSAAYFNNYQTNRAGFSKLFKKLSDEAWSKTIDIIKH 93 Query: 74 QNQRGGRIFL--QDIKKPDCDDWES---GLNAMECALHLEKNVNQSLLELHKLATDK--- 125 +RG ++ K + ++ + L A+ AL +K + + +H+ AT Sbjct: 94 VTKRGDKMNFDQHSTMKTERKNYTAENHELEALAKALDTQKELAERAFYIHREATRNSQH 153 Query: 126 -NDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESG----LAEYLFDKHT 175 +DP + ++E ++ + + I+ L H ++L+K +G LA Y+FD++ Sbjct: 154 LHDPEIAQYLEEEFIEDHAEKIRTLAGHTSDLKKFITANNGHDLSLALYVFDEYL 208 >4ZTT-A nrPDB Length = 166 Score = 123 bits (308), Expect = 6e-29, Method: Composition-based stats. Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 6/155 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N Q+NLELYAS +Y MS + + A + + EE H ++L G Sbjct: 11 LNEQMNLELYASLLYQQMSAWCSYH--TFEGAAAFLRRHAQEEMTHMQRLFDYLTDTGNL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 + ++ P ++ S + E+ + Q + EL A D +F++ Y++ Sbjct: 69 PRINTVESP-FAEYSSLDELFQETYKHEQLITQKINELAHAAMTNQDYPTFNFLQW-YVS 126 Query: 141 EQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHT 175 EQ + K + L G +SG Y DK Sbjct: 127 EQHEEEKLFKSIIDKLSLAG--KSGEGLYFIDKEL 159 >5OUZ-A nrPDB Length = 182 Score = 76.2 bits (186), Expect = 7e-15, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 72/156 (46%), Gaps = 4/156 (2%) Query: 11 QNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKL 70 ++ + D +AI + I++E YAS +L+MS + + L F ++F ++ +E+ HA Sbjct: 16 ESMNPDLLSAIQQHISIERYASVTFLAMSIWCAERE--LAGFYQFFDGEAKDEQSHAVHF 73 Query: 71 MKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHL 130 + R LQ + P +W+S + M A +E + S+ ++ LA +D Sbjct: 74 TQYLIARSQSNDLQTLDAP-RQNWDSLASLMATAFQMEADTTSSIQSVYALAERNSDTRT 132 Query: 131 CDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGL 166 F++ + Q+++ + + ++ + L Sbjct: 133 TVFLDP-LIEAQIQSEDQFAYLLGRVKFANGDPTAL 167 >5ZUR-A nrPDB Length = 158 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 54/143 (37%), Gaps = 5/143 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N+Q+ EL A Y + + K+ +S E +HA++L+ G Sbjct: 11 LNKQLTNELTAINQYFLHARMLNH--WGFDKLGKHEYEESIGEMKHADRLIARIFMLDGL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQD+ K + + C L LE+ + ++ E D D + L+ Sbjct: 69 PNLQDLHKLLIGE--DVPELLACDLKLEQAAHATVREAIAHCESVRDYVSRDLFQ-DILD 125 Query: 141 EQVKAIKELGDHVTNLRKMGAPE 163 + + I L + + K+G Sbjct: 126 DTEEHIDYLETQIDLIDKVGLQN 148 >4E6K-A nrPDB Length = 158 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 5/143 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N+ + EL A Y S ++ D LK + H+S +E +HA+KL++ G Sbjct: 11 LNKILGNELIAINQYFLHSRMWN--DWGLKRLGAHEYHESIDEMKHADKLIERILFLEGL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQD+ K + + ++C L+LE + L E +D D ++ L Sbjct: 69 PNLQDLGKLLIGE--NTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLK-DILE 125 Query: 141 EQVKAIKELGDHVTNLRKMGAPE 163 + + I L + ++K+G Sbjct: 126 SEEEHIDYLETQLGLIQKVGLEN 148 >3BKN-A nrPDB Length = 161 Score = 46.2 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 52/148 (35%), Gaps = 13/148 (8%) Query: 15 QDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQ 74 D +N Q+ EL A Y S +D+ A++ +S EE HAE + Sbjct: 5 PDVLKLLNEQLTSELTAINQYFLHSK--MQDNWGFTELAEHTRAESFEEMRHAETITDRI 62 Query: 75 NQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFI 134 G Q + + E L +E V + L L +K D + Sbjct: 63 LLLDGLPNYQRLFSLRVGQ--TLREQFEADLAIEYEVLERLKPGIVLCREKQDATSARLL 120 Query: 135 ET---------HYLNEQVKAIKELGDHV 153 E YL Q++ + +LGD + Sbjct: 121 EQILADEETHIDYLETQLQLMDKLGDAL 148 >5XX9-A nrPDB Length = 167 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 47/142 (33%), Gaps = 5/142 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N Q+ EL A Y + +D AKY +S +E HAE L G Sbjct: 11 LNEQLTAELTAINQYFLHAK--LQDHKGWTKLAKYTRAESFDEMRHAEVLTDRILLLDGL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 Q + S + +E L ++ K+D + E + Sbjct: 69 PNYQRLFHVRVGQ--SVTEMFQADREVELEAIDRLRRGIEVMRAKHDITSANVFEAILAD 126 Query: 141 EQVKAIKELGDHVTNLRKMGAP 162 E+ I L + + K+G Sbjct: 127 EEHH-IDYLETQLDLIEKLGES 147 >2FKZ-A nrPDB Length = 155 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 5/143 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N+ + EL A Y + + +D L+ K+ H+S +E +HA+KL+K G Sbjct: 11 LNKILGNELIAINQYFLHARMY--EDWGLEKLGKHEYHESIDEMKHADKLIKRILFLEGL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQ++ K + +EC L LE+ L D + +E L Sbjct: 69 PNLQELGKLLIGE--HTKEMLECDLKLEQAGLPDLKAAIAYCESVGDYASRELLE-DILE 125 Query: 141 EQVKAIKELGDHVTNLRKMGAPE 163 + I L + + K+G Sbjct: 126 SEEDHIDWLETQLDLIDKIGLEN 148 >3UOF-A nrPDB Length = 161 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 52/148 (35%), Gaps = 5/148 (3%) Query: 15 QDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQ 74 D +N Q+ EL A Y S +D+ A + +S +E HAE++ Sbjct: 7 PDVLRLLNEQLTSELTAINQYFLHSK--MQDNWGFTELAAHTRAESFDEMRHAEEITDRI 64 Query: 75 NQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFI 134 G Q I + E L +E +V L + +K D + Sbjct: 65 LLLDGLPNYQRIGSLRIGQ--TLREQFEADLAIEYDVLNRLKPGIVMCREKQDTTSAVLL 122 Query: 135 ETHYLNEQVKAIKELGDHVTNLRKMGAP 162 E + ++ + I L + + K+G Sbjct: 123 E-KIVADEEEHIDYLETQLELMDKLGEE 149 >3FVB-A nrPDB Length = 182 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 52/145 (35%), Gaps = 5/145 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N + LEL A Y +Y +D AK +S EE HA+KL+ G Sbjct: 32 LNEALFLELGAVNQYWL--HYRLLNDWGYTRLAKKEREESIEEMHHADKLIDRIIFLEGF 89 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQ + + +E L E + S E ++ D + + L Sbjct: 90 PNLQTVSPLRIGQ--NVKEVLEADLKGEYDARASYKESREICDKLGDY-VSKQLFDELLA 146 Query: 141 EQVKAIKELGDHVTNLRKMGAPESG 165 ++ I L + L K+G G Sbjct: 147 DEEGHIDFLETQLDLLAKIGGERYG 171 >4AM2-A nrPDB Length = 159 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 12/161 (7%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +NR + EL A Y +Y +D K+ AK + +S EE HA+K ++ G Sbjct: 11 LNRGLRSELTAVSQYWL--HYRMLEDWGYKDLAKKWRAESIEEMAHADKFVERILFLEGL 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQ + + +E L E+ E A D + E + Sbjct: 69 PNLQTLDPLRIGQ--TVKEVLESDLAAEREARALYQEGAAYAASVGDFPSKNLFEELMGD 126 Query: 141 EQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDN 181 E+ H+ L S L L+ +H +G D+ Sbjct: 127 EEH--------HIDFLETQLDLVSKLGLELYAQHHIGKLDD 159 >1JGC-A nrPDB Length = 161 Score = 35.4 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 46/123 (37%), Gaps = 6/123 (4%) Query: 21 INRQINLELYASYVYLSMSYYF-DRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGG 79 +N + EL A Y +F ++D L AK +S EE HA+K++ G Sbjct: 11 LNAALRSELTAISQYW---VHFRLQEDWGLAKMAKKSREESIEEMGHADKIIARILFLEG 67 Query: 80 RIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYL 139 LQ + + +EC L E + + E + D + E+ Sbjct: 68 HPNLQKLDPLRIGE--GPRETLECDLAGEHDALKLYREARDYCAEVGDIVSKNIFESLIT 125 Query: 140 NEQ 142 +E+ Sbjct: 126 DEE 128 >3R2L-A nrPDB Length = 154 Score = 35.4 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 56/153 (36%), Gaps = 11/153 (7%) Query: 14 HQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73 H + +N + EL A Y S + +D + H+ EE +HA+ L++ Sbjct: 4 HPEVIDYLNTLLTGELAARDQYFIHSRMY--EDWGFSKLYERLNHEMEEETQHADALLRR 61 Query: 74 QNQRGGRIFLQDIKKPDCDDW---ESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHL 130 + L+ + DD + +E L LE++V +L + L D Sbjct: 62 I------LLLEGTPRMRPDDIHPGTTVPEMLEADLKLERHVRAALAKGIALCEQHKDFVS 115 Query: 131 CDFIETHYLNEQVKAIKELGDHVTNLRKMGAPE 163 D ++ + + L + + +MG Sbjct: 116 RDILKAQLADTEEDHAYWLEQQLGLIARMGLEN 148 >3GVY-A nrPDB Length = 161 Score = 34.6 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 51/146 (34%), Gaps = 5/146 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N + EL A Y +Y ++D + A +S EE HA+KL++ GG Sbjct: 11 LNAALRSELTAVSQYWL--HYRLQEDWGFGSIAHKSRKESIEEMHHADKLIQRIIFLGGH 68 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQ + + ++ L E + +E D + + Sbjct: 69 PNLQRLNPLRIGQ--TLRETLDADLAAEHDARTLYIEARDHCEKVRDYPS-KMLFEELIA 125 Query: 141 EQVKAIKELGDHVTNLRKMGAPESGL 166 ++ I L + + +G G+ Sbjct: 126 DEEGHIDYLETQIDLMGSIGEQNYGM 151 >4CVS-A nrPDB Length = 159 Score = 33.9 bits (76), Expect = 0.048, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 56/143 (39%), Gaps = 5/143 (3%) Query: 21 INRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80 +N+ + EL A Y + F + LK +S +E +HA++ ++ G Sbjct: 12 LNKLLGNELVAINQYFLHARMF--KNWGLKRLNDVEFRESIDEMKHADRYIERILFLEGL 69 Query: 81 IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN 140 LQD+ K + + + L LE + ++L E A D D + L Sbjct: 70 PNLQDLGKLNIGE--DVEEMLRSDLALELDGAKNLREAIGYADSVRDYVSRD-MMIEILR 126 Query: 141 EQVKAIKELGDHVTNLRKMGAPE 163 ++ I L + ++KMG Sbjct: 127 DEEGHIDWLETELDLIQKMGLQN 149 >1JYB-A nrPDB Length = 191 Score = 33.5 bits (75), Expect = 0.060, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 38/110 (34%), Gaps = 4/110 (3%) Query: 48 ALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHL 107 + F + +EREHA++L K + G + D + L A H Sbjct: 38 GFVQISDIFAETADQEREHAKRLFKFL-EGGDLEIVAAFPAGIIADTHANLIASAAGEHH 96 Query: 108 EKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLR 157 E + ++A ++ + + + E+ K D N++ Sbjct: 97 E--YTEMYPSFARIAREEGYEEIARVFASIAVAEEFHE-KRFLDFARNIK 143 >5TX1-M nrPDB Length = 388 Score = 30.8 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 30/84 (35%), Gaps = 5/84 (5%) Query: 57 LHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEK-NVNQSL 115 S EE E++++ Q G +Q+ P + N + +N+ + Sbjct: 308 YALSAEE----ERILRYVQQSVGLFLMQEGATPSAALDMTARNMEPSMYAANRPFINKLM 363 Query: 116 LELHKLATDKNDPHLCDFIETHYL 139 LH+ A D + H+L Sbjct: 364 DYLHRAAAMNTDYFTNAILNPHWL 387 >1K1Y-A nrPDB Length = 659 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 10/68 (14%) Query: 22 NRQINLELYASY---------VYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMK 72 N +INL Y+ Y VYL ++ YF+ + +L + E+ + K K Sbjct: 244 NEKINLMTYSEYLSKFTPRGLVYLPIASYFEMSEWSLPAKQAKLFVEFVEQLKEEGKFEK 303 Query: 73 L-QNQRGG 79 RGG Sbjct: 304 YRVFVRGG 311 >3FLO-A nrPDB Length = 460 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 10/70 (14%) Query: 2 TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSH 61 + STSQ Q + Q NLE + V ++ YF D+ +L+ ++ ++ Sbjct: 128 SPVSTSQELQEF----------QANLEGSSLKVIVTCGPYFANDNFSLELLQEFIDSINN 177 Query: 62 EEREHAEKLM 71 E + H + Sbjct: 178 EVKPHVLIMF 187 >4DRY-A nrPDB Length = 281 Score = 27.7 bits (60), Expect = 2.7, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 65 EHAEKLMKLQNQRGGR-IFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLAT 123 +HA ++MK Q RGGR I I + A + A+ +H +A Sbjct: 152 QHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIAC 211 Query: 124 DKND 127 + D Sbjct: 212 GQID 215 >3LPM-A nrPDB Length = 259 Score = 27.7 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 24/54 (44%), Gaps = 5/54 (9%) Query: 41 YFDRDDVALKNFAKYFLHQSHE---EREHAEKLMKLQNQRGGRIFLQDIKKPDC 91 YF D +LKN ++F HE E ++ ++GG+ + +P+ Sbjct: 129 YFATPDTSLKNTNEHFRIARHEVMCTLEDTIRVAASLLKQGGKANF--VHRPER 180 >2VA1-A nrPDB Length = 256 Score = 27.3 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 20/34 (58%) Query: 115 LLELHKLATDKNDPHLCDFIETHYLNEQVKAIKE 148 ++++ +ND + DFI+ + L EQ++ I + Sbjct: 28 VIKISGACLKQNDSSIIDFIKINDLAEQIEKISK 61 >2E0Z-A nrPDB Length = 345 Score = 26.9 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 5/50 (10%) Query: 25 INLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQ 74 I EL A +Y M+ Y + ++V K L + EE+ H + M L Sbjct: 28 IIAELDAINLYEQMARYSEDENVR-----KILLDVAREEKAHVGEFMALL 72 >4LNS-A nrPDB Length = 351 Score = 26.5 bits (57), Expect = 6.2, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 18/49 (36%) Query: 84 QDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCD 132 D + PD DDW S + A + ++ L L D L + Sbjct: 214 HDARAPDYDDWTSPVEASQVVFPRTSKPIPTMNSLSSLKGLNGDILLYN 262 >1NDS-A nrPDB Length = 330 Score = 26.5 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 89 PDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHL 130 P + + A+ A L V +S+L +H A + PHL Sbjct: 205 PSHAVFNGAVGALTGANALTAAVGESVLIIHSQANRDSRPHL 246 >1X18-E nrPDB Length = 231 Score = 26.5 bits (57), Expect = 6.8, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 37/104 (35%), Gaps = 6/104 (5%) Query: 62 EEREHAEKLMKLQNQRGGRIFLQDIKKPDCD------DWESGLNAMECALHLEKNVNQSL 115 EE E + ++ RGG I KK D + + L +++ Sbjct: 43 EELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTI 102 Query: 116 LELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKM 159 +H+L + + E +++ ++ L +++ R + Sbjct: 103 QRVHRLEELEALFASPEIEERPKKEQRLHELERLQKYLSGFRLL 146 >5UI5-I nrPDB Length = 342 Score = 26.1 bits (56), Expect = 8.0, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 40/102 (39%), Gaps = 12/102 (11%) Query: 57 LHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLL 116 L +E+E A +L+ N++G E + + C++ + V Q +L Sbjct: 27 LELEGKEQELALELLNYLNEKGFL----------SKSVEEISDVLRCSVEELEKVRQKVL 76 Query: 117 ELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRK 158 L L D + +F+E + + L + +L++ Sbjct: 77 RLEPLGVCSKD--VWEFLELQIEEIYPEEEEILKKALRDLKR 116 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.137 0.359 Lambda K H 0.267 0.0418 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,040,149 Number of Sequences: 36641 Number of extensions: 266251 Number of successful extensions: 954 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 79 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 800 Number of HSP's gapped (non-prelim): 108 length of query: 183 length of database: 10,336,785 effective HSP length: 91 effective length of query: 92 effective length of database: 7,002,454 effective search space: 644225768 effective search space used: 644225768 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 56 (26.2 bits)