BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P02774 (474 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1MA9-A nrPDB 929 0.0 4F5V-A nrPDB 149 2e-36 5UJB-A nrPDB 136 2e-32 5ORI-A nrPDB 132 3e-31 5GHK-A nrPDB 131 5e-31 3V03-A nrPDB 130 1e-30 5YXE-A nrPDB 123 2e-28 5HOZ-A nrPDB 119 3e-27 6FAK-A nrPDB 102 5e-22 1YSX-A nrPDB 51 1e-06 5H7C-A nrPDB 33 0.40 5EQZ-A nrPDB 30 1.7 4JUK-A nrPDB 30 1.8 1T5A-A nrPDB 30 2.4 4KWM-A nrPDB 30 2.4 4BGZ-A nrPDB 29 3.7 4MHI-A nrPDB 29 4.8 5LXH-A nrPDB 28 6.7 2R2Q-A nrPDB 28 6.7 >1MA9-A nrPDB Length = 458 Score = 929 bits (2400), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/458 (99%), Positives = 457/458 (99%) Query: 17 LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA 76 LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA Sbjct: 1 LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA 60 Query: 77 EGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTY 136 EGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTY Sbjct: 61 EGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTY 120 Query: 137 VEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT 196 VEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT Sbjct: 121 VEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT 180 Query: 197 VCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE 256 VCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE Sbjct: 181 VCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE 240 Query: 257 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 316 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP Sbjct: 241 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 300 Query: 317 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECC 376 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECC Sbjct: 301 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECC 360 Query: 377 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPT 436 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLP+ATPT Sbjct: 361 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPEATPT 420 Query: 437 ELAKLVNKHSDFASNCCSINSPPLYCDSEIDAELKNIL 474 ELAKLVNK SDFASNCCSINSPPLYCDSEIDAELKNIL Sbjct: 421 ELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL 458 >4F5V-A nrPDB Length = 584 Score = 149 bits (377), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 111/444 (25%), Positives = 200/444 (45%), Gaps = 24/444 (5%) Query: 25 KNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCY 84 K+++ F+ +G+E F L L+ +S+ +E+ ++LVKEV L +AC A+ + +C Sbjct: 4 KSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAANCD 63 Query: 85 DTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEI 144 + K C S + A+CC K+ ER C K + P + P D + Sbjct: 64 KSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEADVL 123 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+AF D K + +++E + + L+ Y + Y +++ CC +A C + Sbjct: 124 CKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTPKLD 183 Query: 205 QLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 LK +L++ R+ C+ +G++ + L++L+Q+ P AD D+ + D+T + Sbjct: 184 ALKEKALISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHK 243 Query: 264 KCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPE- 322 +CC +C A + + +C++ T +S ++CC +K ++ C Y + + P Sbjct: 244 ECCHGDLLEC-ADDRADLAKYMCEHQETISSHLKECC-DKPILEKAHCIYGLHNDETPAG 301 Query: 323 LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVF----LSKVLEPTLKSLG 373 LP V E +KDVC + + K+ +E SRR V L K E TLK Sbjct: 302 LPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLK--- 358 Query: 374 ECCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CADYSENTFTEYKKKLAERLKAK 429 +CC +D C+ + E +D+ + L C Y + ++ L R K Sbjct: 359 KCCATDDPHACYAK----VLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKK 414 Query: 430 LPDATPTELAKLVNKHSDFASNCC 453 +P + L ++ S CC Sbjct: 415 VPQVSTPTLVEISRSLGKVGSKCC 438 Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 91/381 (23%), Positives = 161/381 (42%), Gaps = 22/381 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G + + +LV S++FP F +S++V ++ + + CC G +C D R Sbjct: 200 CASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECC-HGDLLECADDRA 258 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYVEP--TNDEI 144 L+ CE H ECC K LE+ C+ L + P P E + ++ Sbjct: 259 D-LAKYMCEHQETISSH--LKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDV 315 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ + + + +F++EYS + + LL+ K+Y + + CC + P C+ K Sbjct: 316 CKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLD 375 Query: 205 QLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 + + L L + C Y G+ + + L++ +KVP ++ ++ + + S Sbjct: 376 EFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGS 435 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 KCC E+ C+ L +LC + + K CC E + +D C + Sbjct: 436 KCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSE-SLVDRRPCFSALGPD 494 Query: 319 Q--LPELPDVELPT-NKDVCD-PGNTKVMDKYTFELSRRTHLPEVF---LSKVLEPTLKS 371 + +P+ + E T + D+C P + + K T + H P L V+ Sbjct: 495 ETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTAL 554 Query: 372 LGECCDVEDSTTCFNAKGPLL 392 L +CC ED CF +GP L Sbjct: 555 LDKCCSAEDKEACFAVEGPKL 575 >5UJB-A nrPDB Length = 609 Score = 136 bits (343), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 116/468 (24%), Positives = 206/468 (44%), Gaps = 21/468 (4%) Query: 1 MKRVLVLLLAVAFGHALERG---RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTF 57 MK V + L F A RG RD K++V F LG+E+F +L L+ +++ F Sbjct: 1 MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60 Query: 58 EQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGL 117 E +LV EV + C A+ + +C + + K C + + A+CC K+ Sbjct: 61 EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120 Query: 118 ERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVS 177 ER C K P V P D +C AF + + + ++++E + + L+ Sbjct: 121 ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF 180 Query: 178 YTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNL 236 + K Y + CC +A C L + +L+ ++ R+ C+ +GE+ + + Sbjct: 181 FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV 240 Query: 237 IKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKF 296 +L+Q+ P A+ +V L D+T + ++CC +C A + + +C+N + +SK Sbjct: 241 ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLEC-ADDRADLAKYICENQDSISSKL 299 Query: 297 EDCCQEKTAMDVFVCTYFMPAAQLP-ELPDV--ELPTNKDVCD---PGNTKVMDKYTFEL 350 ++CC EK ++ C + ++P +LP + + +KDVC + + +E Sbjct: 300 KECC-EKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEY 358 Query: 351 SRRTHLPEVFLSKVLEPTLK-SLGECCDVEDSTTC----FNAKGPLLKKELSSFIDKGQE 405 +RR V L L T + +L +CC D C F+ PL+ +E + I + E Sbjct: 359 ARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLV-EEPQNLIKQNCE 417 Query: 406 LCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCC 453 L E F + L R K+P + L ++ S CC Sbjct: 418 LFEQLGEYKF---QNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCC 462 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/258 (24%), Positives = 122/258 (47%), Gaps = 17/258 (6%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ F + ++ S++FP F +VS+LV ++ + CC G +C D R Sbjct: 224 CASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECC-HGDLLECADDRA 282 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKH--QPQEFPT----YVEPTND 142 L+ CE+ + ECC K LE+ C+A +++ P + P+ +VE + Sbjct: 283 D-LAKYICENQDS--ISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVE--SK 337 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 ++C+ + + + F++EY+ + + LL+ K+Y + + CC +A P C+ K Sbjct: 338 DVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKV 397 Query: 203 RLQLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNI 261 + K L L + C + GE K + + L++ +KVP ++ ++ ++ + Sbjct: 398 FDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKV 457 Query: 262 LSKCCESASEDCMAKELP 279 SKCC+ AK +P Sbjct: 458 GSKCCKHPE----AKRMP 471 >5ORI-A nrPDB Length = 583 Score = 132 bits (332), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 107/446 (23%), Positives = 199/446 (44%), Gaps = 21/446 (4%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 D K+++ F+ LG+E+F L L+ +S+ F++ +LVKE+ + C A+ + Sbjct: 1 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 C + + + C+ + + A+CC K+ ER C K + P ++P Sbjct: 61 GCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPK-LKPEP 119 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D +C F+ D K++ ++++E + + L+ Y Y + CC + C L Sbjct: 120 DTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLP 179 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + ++ L ++ R+ C+ +GE+ + ++ +L+QK P AD DV + D+T Sbjct: 180 KIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTK 239 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +CD+ T +SK ++CC +K ++ C + + Sbjct: 240 VHKECCHGDLLEC-ADDRADLAKYICDHQDTLSSKLKECC-DKPVLEKSHCIAEIDKDAV 297 Query: 321 PE-LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLK---S 371 PE LP + + +K+VC + + +E SRR PE +S +L + + Sbjct: 298 PENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRH--PEYAVSVLLRLAKEYEAT 355 Query: 372 LGECCDVEDSTTCFNAKGPLLKK---ELSSFIDKGQELCADYSENTFTEYKKKLAERLKA 428 L +CC ED C+ LK E + I K EL + E F + L R Sbjct: 356 LEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGF---QNALIVRYTR 412 Query: 429 KLPDATPTELAKLVNKHSDFASNCCS 454 K P + L ++ + CC+ Sbjct: 413 KAPQVSTPTLVEISRSLGKVGTKCCA 438 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 90/381 (23%), Positives = 163/381 (42%), Gaps = 22/381 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ + S+ S+KFP F V+++V ++ + + CC G +C D R Sbjct: 199 CASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECC-HGDLLECADDRA 257 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFP--TYVEPTNDEI 144 L+ C+ + ECC K LE+ C+A + P+ P T + E+ Sbjct: 258 D-LAKYICDHQDT--LSSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEV 314 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ +++ + F++EYS + + +S+L+ K Y + + CC P C+ Sbjct: 315 CKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFD 374 Query: 205 QLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 +LKHL L + C + +GE + + +++ +K P ++ ++ + + + Sbjct: 375 KLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGT 434 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVC--TYFMP 316 KCC ES C L +LC + + K CC E + ++ C + Sbjct: 435 KCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTE-SLVNRRPCFSDLTLD 493 Query: 317 AAQLPELPDVELPT-NKDVCD-PGNTKVMDKYTFELSRRTHLPEVF---LSKVLEPTLKS 371 +P+ D E T + D+C P K + K T + H P+ L V+E + Sbjct: 494 ETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAF 553 Query: 372 LGECCDVEDSTTCFNAKGPLL 392 + +CC +D CF +GP L Sbjct: 554 VDKCCAADDKEGCFLLEGPKL 574 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 40/187 (21%), Positives = 78/187 (41%), Gaps = 6/187 (3%) Query: 26 NKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDC 83 K C+ F G+ F + +V Y+RK P + + ++ + + + CCA E C Sbjct: 388 KKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPC 447 Query: 84 YDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAAL----KHQPQEFPTYVEP 139 + S + + C + PV +CCT+ + R+ C + L + P+ F Sbjct: 448 TEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFT 507 Query: 140 TNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCF 199 + +IC + + + E + +A L + +++++ V CC + CF Sbjct: 508 FHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCF 567 Query: 200 LKERLQL 206 L E +L Sbjct: 568 LLEGPKL 574 >5GHK-A nrPDB Length = 584 Score = 131 bits (330), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 104/443 (23%), Positives = 199/443 (44%), Gaps = 22/443 (4%) Query: 25 KNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCY 84 K+++ ++ LG+E F L LV +S+ FE +L KEV +AC AE + +C Sbjct: 4 KSEIAHRYNDLGEEHFRGLVLVAFSQYLQQCPFEDHVKLAKEVTEFAKACAAEESGANCD 63 Query: 85 DTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEI 144 + + K C S + A+CC K+ +R C A K FP V P D + Sbjct: 64 KSLHTLFGDKLCTVASLRDKYGDMADCCEKQEPDRNECFLAHKDDNPGFPPLVAPEPDAL 123 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C AF+ + + + ++++E + + L+ Y + Y + CC +A C + Sbjct: 124 CAAFQDNEQLFLGKYLYEIARRHPYFYAPELLYYAQQYKGVFAECCQAADKAACLGPKIE 183 Query: 205 QLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 L+ LL++ R C+ +G++ + ++ +L+Q+ P AD ++ + D+T + Sbjct: 184 ALREKVLLSSAKERFKCASLQKFGDRAFKAWSVARLSQRFPKADFAEISKVVTDLTKVHK 243 Query: 264 KCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLP-E 322 +CC +C A + + +C+N + ++K ++CC +K ++ C + +LP + Sbjct: 244 ECCHGDLLEC-ADDRADLAKYMCENQDSISTKLKECC-DKPVLEKSQCLAEVERDELPGD 301 Query: 323 LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLK---SLGE 374 LP + + +K+VC + + +E +RR PE +S +L + +L + Sbjct: 302 LPSLAADFVEDKEVCKNYQEAKDVFLGTFLYEYARRH--PEYSVSLLLRLAKEYEATLEK 359 Query: 375 CCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CADYSENTFTEYKKKLAERLKAKL 430 CC +D TC+ + E +D+ Q L C + + ++ L R K Sbjct: 360 CCATDDPPTCYAK----VLDEFKPLVDEPQNLVKTNCELFEKLGEYGFQNALLVRYTKKA 415 Query: 431 PDATPTELAKLVNKHSDFASNCC 453 P + L ++ K + CC Sbjct: 416 PQVSTPTLVEVSRKLGKVGTKCC 438 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 89/384 (23%), Positives = 168/384 (43%), Gaps = 28/384 (7%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G F + S+ S++FP F ++S++V ++ + + CC G +C D R Sbjct: 200 CASLQKFGDRAFKAWSVARLSQRFPKADFAEISKVVTDLTKVHKECC-HGDLLECADDRA 258 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPT----YVEPTND 142 L+ CE+ + ECC K LE+ C+A ++ P + P+ +VE + Sbjct: 259 D-LAKYMCENQDS--ISTKLKECCDKPVLEKSQCLAEVERDELPGDLPSLAADFVE--DK 313 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 E+C+ +++ + F++EY+ + + +SLL+ K Y + + CC + P C+ K Sbjct: 314 EVCKNYQEAKDVFLGTFLYEYARRHPEYSVSLLLRLAKEYEATLEKCCATDDPPTCYAKV 373 Query: 203 RLQLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNI 261 + K L L C + GE + + L++ +K P ++ ++ + + Sbjct: 374 LDEFKPLVDEPQNLVKTNCELFEKLGEYGFQNALLVRYTKKAPQVSTPTLVEVSRKLGKV 433 Query: 262 LSKCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 316 +KCC ES C L +LC + + + CC E + ++ C + Sbjct: 434 GTKCCKKPESERMSCAEDFLSVVLNRLCVLHEKTPVSERVTKCCSE-SLVNRRPCFSGLE 492 Query: 317 AAQ--LPELPDVELPT-NKDVCD-PGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSL 372 + +P+ + E T + D+C P K + K T + H P+ + L+ + Sbjct: 493 VDETYVPKEFNAETFTFHADLCTLPEAEKQVKKQTALVELLKHKPKA-TDEQLKTVMGDF 551 Query: 373 G----ECCDVEDSTTCFNAKGPLL 392 G +CC E+ CF+ +GP L Sbjct: 552 GAFVEKCCAAENKEGCFSEEGPKL 575 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 24 EKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDC 83 E +VCK + K+ F L Y+R+ P + + +L KE + E CCA P C Sbjct: 311 EDKEVCKNYQE-AKDVFLGTFLYEYARRHPEYSVSLLLRLAKEYEATLEKCCATDDPPTC 369 Query: 84 Y 84 Y Sbjct: 370 Y 370 >3V03-A nrPDB Length = 583 Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 103/447 (23%), Positives = 201/447 (44%), Gaps = 23/447 (5%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 D K+++ F LG+E F L L+ +S+ F++ +LV E+ + C A+ + Sbjct: 1 DTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 C + + + C+ S + A+CC K+ ER C + K + P ++P Sbjct: 61 GCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPK-LKPDP 119 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 + +C+ F+ D K++ ++++E + + L+ Y Y + CC + C L Sbjct: 120 NTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLP 179 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + ++ L ++ R+ C+ +GE+ + ++ +L+QK P A+ +V L D+T Sbjct: 180 KIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTK 239 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +CDN T +SK ++CC +K ++ C + + Sbjct: 240 VHKECCHGDLLEC-ADDRADLAKYICDNQDTISSKLKECC-DKPLLEKSHCIAEVEKDAI 297 Query: 321 PE-LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLK---S 371 PE LP + + +KDVC + + +E SRR PE +S +L + + Sbjct: 298 PENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRH--PEYAVSVLLRLAKEYEAT 355 Query: 372 LGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CADYSENTFTEYKKKLAERLK 427 L ECC +D C++ + +L +D+ Q L C + + ++ L R Sbjct: 356 LEECCAKDDPHACYST----VFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYT 411 Query: 428 AKLPDATPTELAKLVNKHSDFASNCCS 454 K+P + L ++ + CC+ Sbjct: 412 RKVPQVSTPTLVEVSRSLGKVGTRCCT 438 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 92/380 (24%), Positives = 165/380 (43%), Gaps = 20/380 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ + S+ S+KFP F +V++LV ++ + + CC G +C D R Sbjct: 199 CASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECC-HGDLLECADDRA 257 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFP--TYVEPTNDEI 144 L+ C++ + ECC K LE+ C+A ++ P+ P T + ++ Sbjct: 258 D-LAKYICDNQDT--ISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDV 314 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ +++ + F++EYS + + +S+L+ K Y + + CC P C+ Sbjct: 315 CKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFD 374 Query: 205 QLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 +LKHL L + C Q+ GE + + +++ +KVP ++ ++ + + + Sbjct: 375 KLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGT 434 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMP-A 317 +CC ES C L +LC + + K CC E + P Sbjct: 435 RCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDE 494 Query: 318 AQLPELPDVELPT-NKDVCD-PGNTKVMDKYTFELSRRTHLP---EVFLSKVLEPTLKSL 372 +P+ D +L T + D+C P K + K T + H P E L V+E + + Sbjct: 495 TYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFV 554 Query: 373 GECCDVEDSTTCFNAKGPLL 392 +CC +D CF +GP L Sbjct: 555 DKCCAADDKEACFAVEGPKL 574 >5YXE-A nrPDB Length = 584 Score = 123 bits (309), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 107/444 (24%), Positives = 195/444 (43%), Gaps = 22/444 (4%) Query: 25 KNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCY 84 ++++ F+ LG+E F L LV +S+ FE +LV EV + C A+ + +C Sbjct: 4 QSEIAHRFNDLGEEHFRGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKGCVADQSAANCE 63 Query: 85 DTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEI 144 + L K C S + A+CC K+ ER C K F V P D + Sbjct: 64 KSLHELLGDKLCTVASLRDKYGEMADCCEKKEPERNECFLQHKDDNPGFGQLVTPEADAM 123 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C AF ++ + + ++++E + + L+ Y + Y + CC +A C + Sbjct: 124 CTAFHENEQRFLGKYLYEIARRHPYFYAPELLYYAEEYKGVFTECCEAADKAACLTPKVD 183 Query: 205 QLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 L+ L ++ R+ C+ +GE+ + ++ +L+QK P A+ ++ L D+ I Sbjct: 184 ALREKVLASSAKERLKCASLQKFGERAFKAWSVARLSQKFPKAEFAEISKLVTDLAKIHK 243 Query: 264 KCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLP-E 322 +CC +C A + + +C+N + ++K ++CC K ++ C + +LP + Sbjct: 244 ECCHGDLLEC-ADDRADLAKYICENQDSISTKLKECCG-KPVLEKSHCISEVERDELPAD 301 Query: 323 LP--DVELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLK---SLGE 374 LP V+ +K+VC + + +E SRR PE +S +L + +L + Sbjct: 302 LPPLAVDFVEDKEVCKNYQEAKDVFLGTFLYEYSRRH--PEYSVSLLLRLAKEYEATLEK 359 Query: 375 CCDVEDSTTC----FNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKL 430 CC +D C F+ PL+ +E + + EL E F + L R K+ Sbjct: 360 CCATDDPPACYAHVFDEFKPLV-EEPHNLVKTNCELFEKLGEYGF---QNALLVRYTKKV 415 Query: 431 PDATPTELAKLVNKHSDFASNCCS 454 P + L ++ S CC+ Sbjct: 416 PQVSTPTLVEVSRSLGKVGSKCCT 439 Score = 88.2 bits (217), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 93/385 (24%), Positives = 167/385 (43%), Gaps = 30/385 (7%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ F + S+ S+KFP F ++S+LV ++ + + CC G +C D R Sbjct: 200 CASLQKFGERAFKAWSVARLSQKFPKAEFAEISKLVTDLAKIHKECC-HGDLLECADDRA 258 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFP----TYVEPTND 142 L+ CE+ + ECC K LE+ C++ ++ P + P +VE + Sbjct: 259 D-LAKYICENQDS--ISTKLKECCGKPVLEKSHCISEVERDELPADLPPLAVDFVE--DK 313 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 E+C+ +++ + F++EYS + + +SLL+ K Y + + CC + P C+ Sbjct: 314 EVCKNYQEAKDVFLGTFLYEYSRRHPEYSVSLLLRLAKEYEATLEKCCATDDPPACYAHV 373 Query: 203 RLQLKHLSLLTTLSNRV---CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDIT 259 + K L+ N V C + GE + + L++ +KVP ++ ++ + Sbjct: 374 FDEFK--PLVEEPHNLVKTNCELFEKLGEYGFQNALLVRYTKKVPQVSTPTLVEVSRSLG 431 Query: 260 NILSKCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYF 314 + SKCC E+ C L +LC + + + CC E + ++ C Sbjct: 432 KVGSKCCTHPEAERLSCAEDYLSVVLNRLCVLHEKTPVSERVTKCCTE-SLVNRRPCFSA 490 Query: 315 MPAAQ--LPELPDVELPT-NKDVCD-PGNTKVMDKYTFELSRRTHLP---EVFLSKVLEP 367 + + +P+ E T + D+C P K + K + + H P E L V+ Sbjct: 491 LQVDETYVPKEFSAETFTFHADLCTLPEAEKQIKKQSALVELLKHKPKATEEQLKTVMGD 550 Query: 368 TLKSLGECCDVEDSTTCFNAKGPLL 392 + +CC ED CF +GP L Sbjct: 551 FGSFVDKCCAAEDKEACFAEEGPKL 575 Score = 35.4 bits (80), Expect = 0.055, Method: Compositional matrix adjust. Identities = 68/269 (25%), Positives = 107/269 (39%), Gaps = 19/269 (7%) Query: 24 EKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDC 83 E +VCK + K+ F L YSR+ P + + +L KE + E CCA P C Sbjct: 311 EDKEVCKNYQE-AKDVFLGTFLYEYSRRHPEYSVSLLLRLAKEYEATLEKCCATDDPPAC 369 Query: 84 YDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDE 143 Y E ++ + E + G + L + K PQ PT E Sbjct: 370 YAHVFDEFKPLVEEPHNLVKTNCELFEKLGEYGFQNALLVRYTKKVPQ----VSTPTLVE 425 Query: 144 ICEAFRKDPKEYANQFMWEY---STNYGQAPLSLL-VSYTKSYLS-MVGSCCTSA--SPT 196 + + K + E + +Y L+ L V + K+ +S V CCT + + Sbjct: 426 VSRSLGKVGSKCCTHPEAERLSCAEDYLSVVLNRLCVLHEKTPVSERVTKCCTESLVNRR 485 Query: 197 VCF----LKERLQLKHLSLLT-TLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDV 251 CF + E K S T T +C+ A + K + S L++L + P A E + Sbjct: 486 PCFSALQVDETYVPKEFSAETFTFHADLCTLPEAEKQIKKQ-SALVELLKHKPKATEEQL 544 Query: 252 LPLAEDITNILSKCCESAS-EDCMAKELP 279 + D + + KCC + E C A+E P Sbjct: 545 KTVMGDFGSFVDKCCAAEDKEACFAEEGP 573 >5HOZ-A nrPDB Length = 583 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 105/446 (23%), Positives = 196/446 (43%), Gaps = 19/446 (4%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 D K+++ F+ LG++ F L LV +S+ FE +LV EV + C A+ + Sbjct: 1 DTHKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAE 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 +C + + K C + + A+CC K+ ER C K P ++P Sbjct: 61 NCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPK-LKPEP 119 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D C AF++DP ++ ++++E + + L+ + + Y + CC + C + Sbjct: 120 DAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIP 179 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + LK LL++ R+ CS + +GE+ + ++ +L+QK P AD +V + D+T Sbjct: 180 KLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTK 239 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +C++ + + K + CC +K + C + L Sbjct: 240 VHKECCHGDLLEC-ADDRADLAKYICEHQDSISGKLKACC-DKPLLQKSHCIAEVKEDDL 297 Query: 321 P-ELPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEV-FLSKVLEPTLKSLG 373 P +LP + + +K++C + + +E SRR V L ++ + +L Sbjct: 298 PSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLE 357 Query: 374 ECCDVEDSTTC----FNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAK 429 +CC D C F+ PL+ +E S + K +L + E F + L R K Sbjct: 358 KCCAEADPPACYRTVFDQFTPLV-EEPKSLVKKNCDLFEEVGEYDF---QNALIVRYTKK 413 Query: 430 LPDATPTELAKLVNKHSDFASNCCSI 455 P + L ++ S CC + Sbjct: 414 APQVSTPTLVEIGRTLGKVGSRCCKL 439 Score = 92.4 bits (228), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 91/390 (23%), Positives = 156/390 (40%), Gaps = 40/390 (10%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C F + G+ + S+ S+KFP F +VS++V ++ + + CC G +C D R Sbjct: 199 CSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECC-HGDLLECADDRA 257 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYVE--PTNDEI 144 L+ CE + CC K L++ C+A +K P + P + EI Sbjct: 258 D-LAKYICEHQDS--ISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEI 314 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ ++ + F++EYS + +SLL+ K+Y + + CC A P C+ R Sbjct: 315 CKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACY---RT 371 Query: 205 QLKHLSLLT----TLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + L +L + C + GE + + +++ +K P ++ + + Sbjct: 372 VFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGK 431 Query: 261 ILSKCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFM 315 + S+CC ES C L +LC + + K CC + A Sbjct: 432 VGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAER-------R 484 Query: 316 PAAQLPELPDVELPT---------NKDVCD-PGNTKVMDKYTFELSRRTHLPEVF---LS 362 P EL + +P + D+C P + K + K + H P+ L Sbjct: 485 PCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLK 544 Query: 363 KVLEPTLKSLGECCDVEDSTTCFNAKGPLL 392 VL + +CC ED CF +GP L Sbjct: 545 TVLGNFSAFVAKCCGAEDKEACFAEEGPKL 574 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 43/188 (22%), Positives = 80/188 (42%), Gaps = 8/188 (4%) Query: 26 NKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDC 83 K C F +G+ DF + +V Y++K P + + ++ + + + CC E C Sbjct: 388 KKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPC 447 Query: 84 YDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEP 139 + + + C + PV +CCT ER+ C +AL+ + P+EF Sbjct: 448 SENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFT 507 Query: 140 TNDEICEAFRKDPKEYANQ-FMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVC 198 + +IC +D K+ Q + E + +A L + ++ + V CC + C Sbjct: 508 FHADIC-TLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEAC 566 Query: 199 FLKERLQL 206 F +E +L Sbjct: 567 FAEEGPKL 574 >6FAK-A nrPDB Length = 586 Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 94/447 (21%), Positives = 187/447 (41%), Gaps = 19/447 (4%) Query: 21 RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGAD 80 RD E ++F +++ ++++ +++ TFE++ +LVK++V + C A+ Sbjct: 6 RDIENFNSTQKFI---EDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTL 62 Query: 81 PDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEF-PTYVEP 139 P+C + L K C + P + CC+K +R+LC K F P + Sbjct: 63 PECSKLPNNVLQEKIC-AMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTL 121 Query: 140 TNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCF 199 +E C+A+ + + N F++E + L++ + + SCC + C Sbjct: 122 DPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCL 181 Query: 200 LKERLQL-KHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDI 258 + + ++L ++ VC +G K + L+QK P + ++++ L ED+ Sbjct: 182 QTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDV 241 Query: 259 TNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 ++ CCE C+ ++ + +C + +SK ++CC++K + C Sbjct: 242 SSNYDGCCEGDVVQCI-RDTSKVMNHICSKQDSISSKIKECCEKKIP-ERGQCIINSNKD 299 Query: 319 QLPE---LPDVELPTNKDVC---DPGNTKVMDKYTFELSRR---THLPEVFLSKVLEPTL 369 P+ L + + +++VC D K+TFE SRR +PE L ++++ Sbjct: 300 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPE--LLRIVQIYK 357 Query: 370 KSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAK 429 L CC+ E+ C+ + + Q+ C + K RL Sbjct: 358 DLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKI 417 Query: 430 LPDATPTELAKLVNKHSDFASNCCSIN 456 P + EL L K + CC+++ Sbjct: 418 APQLSTEELVSLGEKMVTAFTTCCTLS 444 Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 82/396 (20%), Positives = 159/396 (40%), Gaps = 21/396 (5%) Query: 10 AVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVS 69 A+ L+ Y+K+ VC G + + + + S+KFP F+++ LV++V S Sbjct: 185 AIPVTQYLKAFSSYQKH-VCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSS 243 Query: 70 LTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCM--AALK 127 + CC EG C + ++ + +S + ECC K+ ER C+ + Sbjct: 244 NYDGCC-EGDVVQCIRDTSKVMNHICSKQDS---ISSKIKECCEKKIPERGQCIINSNKD 299 Query: 128 HQPQEFPTYVEPTND--EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSM 185 +P++ D +C+ DP + +F +EYS + + L+ + Y + Sbjct: 300 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDL 359 Query: 186 VGSCCTSASPTVCFLKERLQLKHLSLLT-TLSNRVCSQYAAYGEKKSRLSNLIKLAQKVP 244 + +CC + +P C+ + + + + + C + G+ + LI+L + P Sbjct: 360 LRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAP 419 Query: 245 TADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTV-KLC--DNLSTKNSKFEDCCQ 301 E+++ L E + + CC + E L + +LC + T N + CC+ Sbjct: 420 QLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCK 479 Query: 302 EKTAMDVFVCTYFMPAAQL---PELPDVELPTNKDVCDPGNTKVM---DKYTFELSRRTH 355 A C + A + P + D+C N ++ D++ L + H Sbjct: 480 TNFAFRR-PCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKH 538 Query: 356 -LPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGP 390 L + L + + +CC E CFN + P Sbjct: 539 ELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESP 574 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 11/31 (35%), Positives = 18/31 (58%) Query: 429 KLPDATPTELAKLVNKHSDFASNCCSINSPP 459 + PD + EL ++V + D NCC+ +PP Sbjct: 340 RHPDLSIPELLRIVQIYKDLLRNCCNTENPP 370 >1YSX-A nrPDB Length = 201 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 6/184 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C+ F LG+ F + LV Y++K P + + ++ + + + CC E C + Sbjct: 8 CELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAED 67 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPTND 142 S + + C + PV +CCT+ + R+ C +AL+ + P+EF + Sbjct: 68 YLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHA 127 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 +IC K+ + + E + +A L + + + V CC + CF +E Sbjct: 128 DICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE 187 Query: 203 RLQL 206 +L Sbjct: 188 GKKL 191 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 215 LSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCM 274 L + C + GE K + + L++ +KVP ++ ++ ++ + SKCC+ Sbjct: 3 LIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPE---- 58 Query: 275 AKELP 279 AK +P Sbjct: 59 AKRMP 63 >5H7C-A nrPDB Length = 404 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 70/316 (22%), Positives = 113/316 (35%), Gaps = 62/316 (19%) Query: 26 NKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQV--SQLVKEVVSLTEACCAEGADPD- 82 N++ K+ + + KE T LV+Y K + +Q S+LV E+V E D + Sbjct: 95 NEIVKQLAEVAKE-ATDKELVIYIVKILAELAKQSTDSELVNEIVKQLAEVAKEATDKEL 153 Query: 83 -CYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLC------MAALKHQPQ---- 131 Y + A AK + E KE +++L + L+ Q Sbjct: 154 VIYIVKILAELAKQSTDSELVNEIVKQLEEVAKEATDKELVEHIEKILEELEQQSAFYEI 213 Query: 132 -EFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCC 190 P E + ++ + DP + AN S N QA L+ Sbjct: 214 LSLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKSLNVNQAV---------KQLAEKAKEA 264 Query: 191 TSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGE-------------------KKS 231 T + +KE +L S + L N + Q A + K+S Sbjct: 265 TDKEEVIEIVKELAELAKQSTDSELVNEIVKQLAEVAKEATDKELVIYIVKILAELAKQS 324 Query: 232 RLSNLI-----KLAQKVPTA-DLEDVL----PLAE--------DITNILSKCCESASEDC 273 S L+ +LA+ A D E V+ LAE ++ N + K E +++ Sbjct: 325 TDSELVNEIVKQLAEVAKEATDKELVIYIVKILAELAKQSTDSELVNEIVKQLEEVAKEA 384 Query: 274 MAKELPEHTVKLCDNL 289 KEL EH K+ + L Sbjct: 385 TDKELVEHIEKILEEL 400 >5EQZ-A nrPDB Length = 146 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 393 KKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELA-KLVNKHSDF 448 KKE+ S ++ L D S F +YK K+ E LK L D EL KL+N + F Sbjct: 13 KKEIDSLMEDVLALVNDSSGGKFKDYKDKINE-LKENLKDIGNAELKEKLLNLQNSF 68 >4JUK-A nrPDB Length = 329 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 5/105 (4%) Query: 256 EDITNILSK-CCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYF 314 E + I+ K + ++D + K H KLCD K +DC + +C F Sbjct: 20 EQVDTIMEKNVTVTHAQDILEKT---HNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEF 76 Query: 315 MPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEV 359 + + + + P N D+C PGN ++ LSR H ++ Sbjct: 77 INVPEWSYIVEKANPAN-DLCYPGNFNDYEELKHLLSRINHFEKI 120 >1T5A-A nrPDB Length = 567 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%) Query: 52 FPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAEC 111 F GT E ++ +K V + TE+ + DP Y AL K E + GTAE Sbjct: 112 FSHGTHEYHAETIKNVRTATESFAS---DPILYRPVAVALDTKGPEIRTGLIKGSGTAEV 168 Query: 112 CTKEGLERKLCM 123 K+G K+ + Sbjct: 169 ELKKGATLKITL 180 >4KWM-A nrPDB Length = 329 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 5/105 (4%) Query: 256 EDITNILSK-CCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYF 314 E + I+ K + ++D + K H KLCD K DC + +C F Sbjct: 18 EQVDTIMEKNVTVTHAQDILEKT---HNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEF 74 Query: 315 MPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEV 359 + + + + P N D+C PGN ++ LSR H ++ Sbjct: 75 INVPEWSYIVEKANPAN-DLCYPGNFNDYEELKHLLSRINHFEKI 118 >4BGZ-A nrPDB Length = 327 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 5/105 (4%) Query: 256 EDITNILSK-CCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYF 314 E + I+ K + ++D + K H KLCD K DC + +C F Sbjct: 15 EQVDTIMEKNVTVTHAQDILEKT---HNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEF 71 Query: 315 MPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEV 359 + + + + P N D+C PGN ++ LSR H ++ Sbjct: 72 LNVPEWSYIVEKINPAN-DLCYPGNFNDYEELKHLLSRINHFEKI 115 >4MHI-A nrPDB Length = 334 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 5/105 (4%) Query: 256 EDITNILSK-CCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYF 314 E + I+ K + ++D + K H KLCD K DC + +C F Sbjct: 18 EQVDTIMEKNVTVTHAQDILEKT---HNGKLCDLNGVKPLILRDCSVAGWLLGNPMCDEF 74 Query: 315 MPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEV 359 + + + + P N D+C PG+ ++ LSR H ++ Sbjct: 75 INVPEWSYIVEKASPAN-DLCYPGDFNDYEELKHLLSRTNHFEKI 118 >5LXH-A nrPDB Length = 123 Score = 28.5 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 410 YSENTFTEYKKKLAERLKAKLPDATPTELAK 440 Y E+ EY+KK E+++ K PD P + K Sbjct: 11 YKEDHPFEYRKKEGEKIRKKYPDRVPVIVEK 41 >2R2Q-A nrPDB Length = 110 Score = 28.5 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 410 YSENTFTEYKKKLAERLKAKLPDATPTELAK 440 Y E+ EY+KK E+++ K PD P + K Sbjct: 4 YKEDHPFEYRKKEGEKIRKKYPDRVPVIVEK 34 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5UJB-A nrPDB 570 e-163 1MA9-A nrPDB 569 e-162 5GHK-A nrPDB 555 e-158 5ORI-A nrPDB 554 e-158 5YXE-A nrPDB 552 e-157 3V03-A nrPDB 548 e-156 4F5V-A nrPDB 547 e-156 5HOZ-A nrPDB 538 e-153 6FAK-A nrPDB 480 e-136 1YSX-A nrPDB 178 5e-45 Sequences not found previously or not previously below threshold: 6O85-E nrPDB 31 1.1 3UX1-A nrPDB 29 3.2 3Q5I-A nrPDB 29 4.0 CONVERGED! >5UJB-A nrPDB Length = 609 Score = 570 bits (1469), Expect = e-163, Method: Composition-based stats. Identities = 112/468 (23%), Positives = 203/468 (43%), Gaps = 19/468 (4%) Query: 1 MKRVLVLLLAVAFGHALERG---RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTF 57 MK V + L F A RG RD K++V F LG+E+F +L L+ +++ F Sbjct: 1 MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60 Query: 58 EQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGL 117 E +LV EV + C A+ + +C + + K C + + A+CC K+ Sbjct: 61 EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120 Query: 118 ERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVS 177 ER C K P V P D +C AF + + + ++++E + + L+ Sbjct: 121 ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF 180 Query: 178 YTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNL 236 + K Y + CC +A C L + +L+ ++ R+ C+ +GE+ + + Sbjct: 181 FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV 240 Query: 237 IKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKF 296 +L+Q+ P A+ +V L D+T + ++CC +C A + + +C+N + +SK Sbjct: 241 ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLEC-ADDRADLAKYICENQDSISSKL 299 Query: 297 EDCCQEKTAMDVFVCTYFMPAAQLP-ELPDV--ELPTNKDVCD---PGNTKVMDKYTFEL 350 ++CC EK ++ C + ++P +LP + + +KDVC + + +E Sbjct: 300 KECC-EKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEY 358 Query: 351 SRRTHLPEVF-LSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLK---KELSSFIDKGQEL 406 +RR V L ++ + +L +CC D C+ K +E + I + EL Sbjct: 359 ARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCEL 418 Query: 407 CADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCS 454 E F + L R K+P + L ++ S CC Sbjct: 419 FEQLGEYKF---QNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCK 463 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 6/184 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C+ F LG+ F + LV Y++K P + + ++ + + + CC E C + Sbjct: 416 CELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAED 475 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPTND 142 S + + C + PV +CCT+ + R+ C +AL+ + P+EF + Sbjct: 476 YLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHA 535 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 +IC K+ + + E + +A L + + + V CC + CF +E Sbjct: 536 DICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE 595 Query: 203 RLQL 206 +L Sbjct: 596 GKKL 599 Score = 136 bits (342), Expect = 2e-32, Method: Composition-based stats. Identities = 83/381 (21%), Positives = 158/381 (41%), Gaps = 22/381 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ F + ++ S++FP F +VS+LV ++ + CC G +C D R Sbjct: 224 CASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECC-HGDLLECADDRA 282 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYV--EPTNDEI 144 L+ CE+ + ECC K LE+ C+A +++ P + P+ + ++ Sbjct: 283 D-LAKYICENQD--SISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDV 339 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ + + + F++EY+ + + LL+ K+Y + + CC +A P C+ K Sbjct: 340 CKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFD 399 Query: 205 QLKHLSLL-TTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 + K L L + C + GE K + + L++ +KVP ++ ++ ++ + S Sbjct: 400 EFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGS 459 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 KCC E+ C L +LC + + + CC E + ++ C + Sbjct: 460 KCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTE-SLVNRRPCFSALEVD 518 Query: 319 QL---PELPDVELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVFLSK-VLEPTLKS 371 + E + D+C + EL + K V++ Sbjct: 519 ETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAF 578 Query: 372 LGECCDVEDSTTCFNAKGPLL 392 + +CC +D TCF +G L Sbjct: 579 VEKCCKADDKETCFAEEGKKL 599 Score = 32.0 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 62/403 (15%), Positives = 118/403 (29%), Gaps = 63/403 (15%) Query: 108 TAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRK-DPKEYANQFMWEYSTN 166 ECC + ++ C+ + ++ C + +K + + + S Sbjct: 189 FTECC--QAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQR 246 Query: 167 YGQAPLSLLVSYTKSYLSMVGSCCT------SAS-------------------PTVCFLK 201 + +A + + + CC + C Sbjct: 247 FPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKP 306 Query: 202 ERLQ---------------LKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTA 246 + L L+ S VC YA + L + A++ P Sbjct: 307 LLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAE-AKDVFLGMFLYEYARRHPDY 365 Query: 247 DLEDVLPLAEDITNILSKCCES-ASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTA 305 + +L LA+ L KCC + +C AK E + + + + C+ Sbjct: 366 SVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLI----KQNCELFEQ 421 Query: 306 MDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVL 365 + + + ++P V PT +V ++R E +LS VL Sbjct: 422 LGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVL 481 Query: 366 E---------PTLKSLGECCDVE--DSTTCFNAKGPLLKKELSSFIDKGQELCADYSENT 414 P + +CC + CF+A F + AD + Sbjct: 482 NQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLS 541 Query: 415 FTEYK---KKLAERLKAKLPDATPTELAKLVNKHSDFASNCCS 454 E + + L P AT +L +++ + F CC Sbjct: 542 EKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCK 584 >1MA9-A nrPDB Length = 458 Score = 569 bits (1465), Expect = e-162, Method: Composition-based stats. Identities = 456/458 (99%), Positives = 457/458 (99%) Query: 17 LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA 76 LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA Sbjct: 1 LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA 60 Query: 77 EGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTY 136 EGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTY Sbjct: 61 EGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTY 120 Query: 137 VEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT 196 VEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT Sbjct: 121 VEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPT 180 Query: 197 VCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE 256 VCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE Sbjct: 181 VCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE 240 Query: 257 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 316 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP Sbjct: 241 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 300 Query: 317 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECC 376 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECC Sbjct: 301 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECC 360 Query: 377 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPT 436 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLP+ATPT Sbjct: 361 DVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPEATPT 420 Query: 437 ELAKLVNKHSDFASNCCSINSPPLYCDSEIDAELKNIL 474 ELAKLVNK SDFASNCCSINSPPLYCDSEIDAELKNIL Sbjct: 421 ELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL 458 >5GHK-A nrPDB Length = 584 Score = 555 bits (1431), Expect = e-158, Method: Composition-based stats. Identities = 102/445 (22%), Positives = 198/445 (44%), Gaps = 18/445 (4%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 + K+++ ++ LG+E F L LV +S+ FE +L KEV +AC AE + Sbjct: 1 EAYKSEIAHRYNDLGEEHFRGLVLVAFSQYLQQCPFEDHVKLAKEVTEFAKACAAEESGA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 +C + + K C S + A+CC K+ +R C A K FP V P Sbjct: 61 NCDKSLHTLFGDKLCTVASLRDKYGDMADCCEKQEPDRNECFLAHKDDNPGFPPLVAPEP 120 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D +C AF+ + + + ++++E + + L+ Y + Y + CC +A C Sbjct: 121 DALCAAFQDNEQLFLGKYLYEIARRHPYFYAPELLYYAQQYKGVFAECCQAADKAACLGP 180 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + L+ LL++ R C+ +G++ + ++ +L+Q+ P AD ++ + D+T Sbjct: 181 KIEALREKVLLSSAKERFKCASLQKFGDRAFKAWSVARLSQRFPKADFAEISKVVTDLTK 240 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +C+N + ++K ++CC +K ++ C + +L Sbjct: 241 VHKECCHGDLLEC-ADDRADLAKYMCENQDSISTKLKECC-DKPVLEKSQCLAEVERDEL 298 Query: 321 P-ELPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVF-LSKVLEPTLKSLG 373 P +LP + + +K+VC + + +E +RR V L ++ + +L Sbjct: 299 PGDLPSLAADFVEDKEVCKNYQEAKDVFLGTFLYEYARRHPEYSVSLLLRLAKEYEATLE 358 Query: 374 ECCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CADYSENTFTEYKKKLAERLKAK 429 +CC +D TC+ + E +D+ Q L C + + ++ L R K Sbjct: 359 KCCATDDPPTCYA----KVLDEFKPLVDEPQNLVKTNCELFEKLGEYGFQNALLVRYTKK 414 Query: 430 LPDATPTELAKLVNKHSDFASNCCS 454 P + L ++ K + CC Sbjct: 415 APQVSTPTLVEVSRKLGKVGTKCCK 439 Score = 155 bits (392), Expect = 4e-38, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 78/184 (42%), Gaps = 6/184 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C+ F LG+ F + LV Y++K P + + ++ +++ + CC E C + Sbjct: 392 CELFEKLGEYGFQNALLVRYTKKAPQVSTPTLVEVSRKLGKVGTKCCKKPESERMSCAED 451 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPTND 142 S + + C + PV +CC++ + R+ C + L+ + P+EF + Sbjct: 452 FLSVVLNRLCVLHEKTPVSERVTKCCSESLVNRRPCFSGLEVDETYVPKEFNAETFTFHA 511 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 ++C + + + E + +A L + + + V CC + + CF +E Sbjct: 512 DLCTLPEAEKQVKKQTALVELLKHKPKATDEQLKTVMGDFGAFVEKCCAAENKEGCFSEE 571 Query: 203 RLQL 206 +L Sbjct: 572 GPKL 575 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 85/399 (21%), Positives = 159/399 (39%), Gaps = 29/399 (7%) Query: 11 VAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSL 70 V A ER + C G F + S+ S++FP F ++S++V ++ + Sbjct: 189 VLLSSAKERFK-------CASLQKFGDRAFKAWSVARLSQRFPKADFAEISKVVTDLTKV 241 Query: 71 TEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ- 129 + CC G +C D R L+ CE+ ECC K LE+ C+A ++ Sbjct: 242 HKECC-HGDLLECADDRAD-LAKYMCENQDSISTK--LKECCDKPVLEKSQCLAEVERDE 297 Query: 130 -PQEFPTYV--EPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMV 186 P + P+ + E+C+ +++ + F++EY+ + + +SLL+ K Y + + Sbjct: 298 LPGDLPSLAADFVEDKEVCKNYQEAKDVFLGTFLYEYARRHPEYSVSLLLRLAKEYEATL 357 Query: 187 GSCCTSASPTVCFLKERLQLKHLS-LLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPT 245 CC + P C+ K + K L L C + GE + + L++ +K P Sbjct: 358 EKCCATDDPPTCYAKVLDEFKPLVDEPQNLVKTNCELFEKLGEYGFQNALLVRYTKKAPQ 417 Query: 246 ADLEDVLPLAEDITNILSKCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCC 300 ++ ++ + + +KCC ES C L +LC + + + CC Sbjct: 418 VSTPTLVEVSRKLGKVGTKCCKKPESERMSCAEDFLSVVLNRLCVLHEKTPVSERVTKCC 477 Query: 301 QEKTAMDVFVCTYFMPAAQL---PELPDVELPTNKDVC---DPGNTKVMDKYTFELSRRT 354 E + ++ C + + E + D+C + EL + Sbjct: 478 SE-SLVNRRPCFSGLEVDETYVPKEFNAETFTFHADLCTLPEAEKQVKKQTALVELLKHK 536 Query: 355 HLP-EVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLL 392 + L V+ + +CC E+ CF+ +GP L Sbjct: 537 PKATDEQLKTVMGDFGAFVEKCCAAENKEGCFSEEGPKL 575 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 50/305 (16%), Positives = 106/305 (34%), Gaps = 22/305 (7%) Query: 184 SMVGSCCTSA--SPTVCFLK-ERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLA 240 + CC CFL + L+ + +C+ + E+ L ++A Sbjct: 85 GDMADCCEKQEPDRNECFLAHKDDNPGFPPLVAPEPDALCAAFQD-NEQLFLGKYLYEIA 143 Query: 241 QKVPTADLEDVLPLAEDITNILSKCCES-ASEDCMAKELPEHTVKLCDNLSTKNSKFEDC 299 ++ P ++L A+ + ++CC++ C+ ++ K+ LS+ +F+ Sbjct: 144 RRHPYFYAPELLYYAQQYKGVFAECCQAADKAACLGPKIEALREKVL--LSSAKERFKCA 201 Query: 300 CQEKTAMDVFVCTYFMPAAQLPELPDVELPTNK----DVCDPGNTKVMDKYTFELSRRTH 355 +K F +Q P + D+ R Sbjct: 202 SLQKFGDRAFKAWSVARLSQR--FPKADFAEISKVVTDLTKVHKECCHGDLLECADDRAD 259 Query: 356 LPEVFLSKVLEPTLKSLGECCDVE--DSTTCFNAKG----PLLKKELSSFIDKGQELCAD 409 L + + K L ECCD + + C P L++ + +E+C + Sbjct: 260 LAKYMCENQDSISTK-LKECCDKPVLEKSQCLAEVERDELPGDLPSLAADFVEDKEVCKN 318 Query: 410 YSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSEIDAE 469 Y E + + P+ + + L +L ++ CC+ + PP C +++ E Sbjct: 319 YQE-AKDVFLGTFLYEYARRHPEYSVSLLLRLAKEYEATLEKCCATDDPPT-CYAKVLDE 376 Query: 470 LKNIL 474 K ++ Sbjct: 377 FKPLV 381 Score = 29.0 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 78/468 (16%), Positives = 143/468 (30%), Gaps = 63/468 (13%) Query: 24 EKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDC 83 E + +C F ++ F L +R+ P ++ ++ + CC C Sbjct: 119 EPDALCAAFQD-NEQLFLGKYLYEIARRHPYFYAPELLYYAQQYKGVFAECCQAADKAAC 177 Query: 84 YDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDE 143 + AL K S++ ER C + K + F + + Sbjct: 178 LGPKIEALREKVLLSSAK----------------ERFKCASLQKFGDRAFKAW---SVAR 218 Query: 144 ICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSAS------PTV 197 + + F K ++ + + + + + L+ + C + Sbjct: 219 LSQRFPKADFAEISKVVTDLTKVHKECCHGDLLECADDRADLAKYMCENQDSISTKLKEC 278 Query: 198 CFLKERLQ---------------LKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQK 242 C + L L+ VC Y + + L + A++ Sbjct: 279 CDKPVLEKSQCLAEVERDELPGDLPSLAADFVEDKEVCKNYQE-AKDVFLGTFLYEYARR 337 Query: 243 VPTADLEDVLPLAEDITNILSKCCESA-SEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQ 301 P + +L LA++ L KCC + C AK L E + + + + C+ Sbjct: 338 HPEYSVSLLLRLAKEYEATLEKCCATDDPPTCYAKVLDEFKPLVDEPQNLVKTN----CE 393 Query: 302 EKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFL 361 + + + + P V PT +V S R E FL Sbjct: 394 LFEKLGEYGFQNALLVRYTKKAPQVSTPTLVEVSRKLGKVGTKCCKKPESERMSCAEDFL 453 Query: 362 SKVLE---------PTLKSLGECCDVE--DSTTCFNAKGPLLKKELSSFIDKG----QEL 406 S VL P + + +CC + CF+ F + +L Sbjct: 454 SVVLNRLCVLHEKTPVSERVTKCCSESLVNRRPCFSGLEVDETYVPKEFNAETFTFHADL 513 Query: 407 CADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCS 454 C + + L E LK K P AT +L ++ F CC+ Sbjct: 514 CTLPEAEKQVKKQTALVELLKHK-PKATDEQLKTVMGDFGAFVEKCCA 560 >5ORI-A nrPDB Length = 583 Score = 554 bits (1427), Expect = e-158, Method: Composition-based stats. Identities = 105/444 (23%), Positives = 197/444 (44%), Gaps = 17/444 (3%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 D K+++ F+ LG+E+F L L+ +S+ F++ +LVKE+ + C A+ + Sbjct: 1 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 C + + + C+ + + A+CC K+ ER C K + P ++P Sbjct: 61 GCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLKHKDDSPDLPK-LKPEP 119 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D +C F+ D K++ ++++E + + L+ Y Y + CC + C L Sbjct: 120 DTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLP 179 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + ++ L ++ R+ C+ +GE+ + ++ +L+QK P AD DV + D+T Sbjct: 180 KIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTK 239 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +CD+ T +SK ++CC +K ++ C + + Sbjct: 240 VHKECCHGDLLEC-ADDRADLAKYICDHQDTLSSKLKECC-DKPVLEKSHCIAEIDKDAV 297 Query: 321 PE-LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEV-FLSKVLEPTLKSLG 373 PE LP + + +K+VC + + +E SRR V L ++ + +L Sbjct: 298 PENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLE 357 Query: 374 ECCDVEDSTTCFNAKGPLLK---KELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKL 430 +CC ED C+ LK E + I K EL + E F + L R K Sbjct: 358 DCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGF---QNALIVRYTRKA 414 Query: 431 PDATPTELAKLVNKHSDFASNCCS 454 P + L ++ + CC+ Sbjct: 415 PQVSTPTLVEISRSLGKVGTKCCA 438 Score = 148 bits (373), Expect = 5e-36, Method: Composition-based stats. Identities = 40/186 (21%), Positives = 78/186 (41%), Gaps = 6/186 (3%) Query: 27 KVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCY 84 K C+ F G+ F + +V Y+RK P + + ++ + + + CCA E C Sbjct: 389 KNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCT 448 Query: 85 DTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPT 140 + S + + C + PV +CCT+ + R+ C + L + P+ F Sbjct: 449 EDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTF 508 Query: 141 NDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFL 200 + +IC + + + E + +A L + +++++ V CC + CFL Sbjct: 509 HADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFL 568 Query: 201 KERLQL 206 E +L Sbjct: 569 LEGPKL 574 Score = 144 bits (364), Expect = 7e-35, Method: Composition-based stats. Identities = 85/389 (21%), Positives = 159/389 (40%), Gaps = 22/389 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ + S+ S+KFP F V+++V ++ + + CC G +C D R Sbjct: 199 CASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECC-HGDLLECADDRA 257 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYV--EPTNDEI 144 L+ C+ ECC K LE+ C+A + P+ P + E+ Sbjct: 258 D-LAKYICDHQDTL--SSKLKECCDKPVLEKSHCIAEIDKDAVPENLPPLTADFAEDKEV 314 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ +++ + F++EYS + + +S+L+ K Y + + CC P C+ Sbjct: 315 CKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFD 374 Query: 205 QLKHLS-LLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 +LKHL L + C + +GE + + +++ +K P ++ ++ + + + Sbjct: 375 KLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGT 434 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 KCC ES C L +LC + + K CC E + ++ C + Sbjct: 435 KCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTE-SLVNRRPCFSDLTLD 493 Query: 319 Q--LPELPDVE-LPTNKDVC---DPGNTKVMDKYTFELSRRTHLP-EVFLSKVLEPTLKS 371 + +P+ D E + D+C D EL + + L V+E + Sbjct: 494 ETYVPKPFDGESFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAF 553 Query: 372 LGECCDVEDSTTCFNAKGPLLKKELSSFI 400 + +CC +D CF +GP L + + Sbjct: 554 VDKCCAADDKEGCFLLEGPKLVASTQAAL 582 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 74/452 (16%), Positives = 137/452 (30%), Gaps = 31/452 (6%) Query: 24 EKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDC 83 E + +C EF ++ F L +R+ P ++ + + + CC C Sbjct: 118 EPDTLCAEFK-ADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGAC 176 Query: 84 YDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDE 143 + + K S++ ++ ER L ++ Q+FP + Sbjct: 177 LLPKIETMREKVLASSARQ----RLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTK 232 Query: 144 ICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSA--SPTVCFLK 201 I K KE + + E + + + + + S + CC + C + Sbjct: 233 IVTDLTKVHKECCHGDLLECADDRADL-AKYICDHQDTLSSKLKECCDKPVLEKSHCIAE 291 Query: 202 -----ERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAE 256 L L+ VC Y + S L + +++ P + +L LA+ Sbjct: 292 IDKDAVPENLPPLTADFAEDKEVCKNYQE-AKDVFLGSFLYEYSRRHPEYAVSVLLRLAK 350 Query: 257 DITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 316 + L CC + + L D K + ++ Sbjct: 351 EYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRY 410 Query: 317 AAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLE---------P 367 + P++ L TK K S R E +LS +L P Sbjct: 411 TRKAPQVSTPTLVEISRSLGKVGTKCCAK---PESERMPCTEDYLSLILNRLCVLHEKTP 467 Query: 368 TLKSLGECCDVE--DSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYK---KKL 422 + + +CC + CF+ F + AD TE + + Sbjct: 468 VSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDGESFTFHADICTLPDTEKQIKKQTA 527 Query: 423 AERLKAKLPDATPTELAKLVNKHSDFASNCCS 454 L P AT +L ++ F CC+ Sbjct: 528 LVELLKHKPKATDEQLKTVMENFVAFVDKCCA 559 >5YXE-A nrPDB Length = 584 Score = 552 bits (1423), Expect = e-157, Method: Composition-based stats. Identities = 103/444 (23%), Positives = 191/444 (43%), Gaps = 16/444 (3%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 + ++++ F+ LG+E F L LV +S+ FE +LV EV + C A+ + Sbjct: 1 EAHQSEIAHRFNDLGEEHFRGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKGCVADQSAA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 +C + L K C S + A+CC K+ ER C K F V P Sbjct: 61 NCEKSLHELLGDKLCTVASLRDKYGEMADCCEKKEPERNECFLQHKDDNPGFGQLVTPEA 120 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D +C AF ++ + + ++++E + + L+ Y + Y + CC +A C Sbjct: 121 DAMCTAFHENEQRFLGKYLYEIARRHPYFYAPELLYYAEEYKGVFTECCEAADKAACLTP 180 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + L+ L ++ R+ C+ +GE+ + ++ +L+QK P A+ ++ L D+ Sbjct: 181 KVDALREKVLASSAKERLKCASLQKFGERAFKAWSVARLSQKFPKAEFAEISKLVTDLAK 240 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 I +CC +C A + + +C+N + ++K ++CC K ++ C + +L Sbjct: 241 IHKECCHGDLLEC-ADDRADLAKYICENQDSISTKLKECCG-KPVLEKSHCISEVERDEL 298 Query: 321 P-ELPD--VELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVF-LSKVLEPTLKSLG 373 P +LP V+ +K+VC + + +E SRR V L ++ + +L Sbjct: 299 PADLPPLAVDFVEDKEVCKNYQEAKDVFLGTFLYEYSRRHPEYSVSLLLRLAKEYEATLE 358 Query: 374 ECCDVEDSTTCFNAKGPLLK---KELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKL 430 +CC +D C+ K +E + + EL E F + L R K+ Sbjct: 359 KCCATDDPPACYAHVFDEFKPLVEEPHNLVKTNCELFEKLGEYGF---QNALLVRYTKKV 415 Query: 431 PDATPTELAKLVNKHSDFASNCCS 454 P + L ++ S CC+ Sbjct: 416 PQVSTPTLVEVSRSLGKVGSKCCT 439 Score = 157 bits (398), Expect = 7e-39, Method: Composition-based stats. Identities = 40/184 (21%), Positives = 77/184 (41%), Gaps = 6/184 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C+ F LG+ F + LV Y++K P + + ++ + + + CC E C + Sbjct: 392 CELFEKLGEYGFQNALLVRYTKKVPQVSTPTLVEVSRSLGKVGSKCCTHPEAERLSCAED 451 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPTND 142 S + + C + PV +CCT+ + R+ C +AL+ + P+EF + Sbjct: 452 YLSVVLNRLCVLHEKTPVSERVTKCCTESLVNRRPCFSALQVDETYVPKEFSAETFTFHA 511 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 ++C + + + E + +A L + + S V CC + CF +E Sbjct: 512 DLCTLPEAEKQIKKQSALVELLKHKPKATEEQLKTVMGDFGSFVDKCCAAEDKEACFAEE 571 Query: 203 RLQL 206 +L Sbjct: 572 GPKL 575 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 85/381 (22%), Positives = 153/381 (40%), Gaps = 22/381 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ F + S+ S+KFP F ++S+LV ++ + + CC G +C D R Sbjct: 200 CASLQKFGERAFKAWSVARLSQKFPKAEFAEISKLVTDLAKIHKECC-HGDLLECADDRA 258 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYV--EPTNDEI 144 L+ CE+ ECC K LE+ C++ ++ P + P + E+ Sbjct: 259 D-LAKYICENQDSISTK--LKECCGKPVLEKSHCISEVERDELPADLPPLAVDFVEDKEV 315 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ +++ + F++EYS + + +SLL+ K Y + + CC + P C+ Sbjct: 316 CKNYQEAKDVFLGTFLYEYSRRHPEYSVSLLLRLAKEYEATLEKCCATDDPPACYAHVFD 375 Query: 205 QLKHLSLLT-TLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 + K L L C + GE + + L++ +KVP ++ ++ + + S Sbjct: 376 EFKPLVEEPHNLVKTNCELFEKLGEYGFQNALLVRYTKKVPQVSTPTLVEVSRSLGKVGS 435 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 KCC E+ C L +LC + + + CC E + ++ C + Sbjct: 436 KCCTHPEAERLSCAEDYLSVVLNRLCVLHEKTPVSERVTKCCTE-SLVNRRPCFSALQVD 494 Query: 319 QL---PELPDVELPTNKDVC---DPGNTKVMDKYTFELSRRTHLP-EVFLSKVLEPTLKS 371 + E + D+C + EL + E L V+ Sbjct: 495 ETYVPKEFSAETFTFHADLCTLPEAEKQIKKQSALVELLKHKPKATEEQLKTVMGDFGSF 554 Query: 372 LGECCDVEDSTTCFNAKGPLL 392 + +CC ED CF +GP L Sbjct: 555 VDKCCAAEDKEACFAEEGPKL 575 Score = 35.5 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 78/468 (16%), Positives = 142/468 (30%), Gaps = 82/468 (17%) Query: 34 HLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSA 93 H ++ F L +R+ P ++ +E + CC C + AL Sbjct: 128 HENEQRFLGKYLYEIARRHPYFYAPELLYYAEEYKGVFTECCEAADKAACLTPKVDALRE 187 Query: 94 KSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPK 153 K S++ ER C + K + F + + + + F K Sbjct: 188 KVLASSAK----------------ERLKCASLQKFGERAFKAW---SVARLSQKFPKAEF 228 Query: 154 EYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE--RLQLKHLSL 211 ++ + + + + + L+ + C + LKE + S Sbjct: 229 AEISKLVTDLAKIHKECCHGDLLECADDRADLAKYICENQDSISTKLKECCGKPVLEKSH 288 Query: 212 LTTLSNR-------------------VCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVL 252 + R VC Y + + L + +++ P + +L Sbjct: 289 CISEVERDELPADLPPLAVDFVEDKEVCKNYQE-AKDVFLGTFLYEYSRRHPEYSVSLLL 347 Query: 253 PLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCT 312 LA++ L KCC + P + D +F+ +E + C Sbjct: 348 RLAKEYEATLEKCC-------ATDDPPACYAHVFD-------EFKPLVEEPHNLVKTNCE 393 Query: 313 YFMPAAQ-----------LPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFL 361 F + ++P V PT +V T + R E +L Sbjct: 394 LFEKLGEYGFQNALLVRYTKKVPQVSTPTLVEVSRSLGKVGSKCCTHPEAERLSCAEDYL 453 Query: 362 SKVLE---------PTLKSLGECCDVE--DSTTCFNAKGPLLKKELSSFIDKG----QEL 406 S VL P + + +CC + CF+A F + +L Sbjct: 454 SVVLNRLCVLHEKTPVSERVTKCCTESLVNRRPCFSALQVDETYVPKEFSAETFTFHADL 513 Query: 407 CADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCS 454 C + + L E LK K P AT +L ++ F CC+ Sbjct: 514 CTLPEAEKQIKKQSALVELLKHK-PKATEEQLKTVMGDFGSFVDKCCA 560 >3V03-A nrPDB Length = 583 Score = 548 bits (1413), Expect = e-156, Method: Composition-based stats. Identities = 101/444 (22%), Positives = 197/444 (44%), Gaps = 17/444 (3%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 D K+++ F LG+E F L L+ +S+ F++ +LV E+ + C A+ + Sbjct: 1 DTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 C + + + C+ S + A+CC K+ ER C + K + P ++P Sbjct: 61 GCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPK-LKPDP 119 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 + +C+ F+ D K++ ++++E + + L+ Y Y + CC + C L Sbjct: 120 NTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLP 179 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + ++ L ++ R+ C+ +GE+ + ++ +L+QK P A+ +V L D+T Sbjct: 180 KIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTK 239 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +CDN T +SK ++CC +K ++ C + + Sbjct: 240 VHKECCHGDLLEC-ADDRADLAKYICDNQDTISSKLKECC-DKPLLEKSHCIAEVEKDAI 297 Query: 321 PE-LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEV-FLSKVLEPTLKSLG 373 PE LP + + +KDVC + + +E SRR V L ++ + +L Sbjct: 298 PENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLE 357 Query: 374 ECCDVEDSTTCFNAKGPLLK---KELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKL 430 ECC +D C++ LK E + I + C + + ++ L R K+ Sbjct: 358 ECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQN---CDQFEKLGEYGFQNALIVRYTRKV 414 Query: 431 PDATPTELAKLVNKHSDFASNCCS 454 P + L ++ + CC+ Sbjct: 415 PQVSTPTLVEVSRSLGKVGTRCCT 438 Score = 152 bits (383), Expect = 4e-37, Method: Composition-based stats. Identities = 39/184 (21%), Positives = 78/184 (42%), Gaps = 6/184 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C +F LG+ F + +V Y+RK P + + ++ + + + CC E C + Sbjct: 391 CDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTED 450 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPTND 142 S + + C + PV +CCT+ + R+ C +AL + P+ F + + Sbjct: 451 YLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHA 510 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 +IC + + + E + +A L + +++++ V CC + CF E Sbjct: 511 DICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVE 570 Query: 203 RLQL 206 +L Sbjct: 571 GPKL 574 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 84/389 (21%), Positives = 160/389 (41%), Gaps = 22/389 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G+ + S+ S+KFP F +V++LV ++ + + CC G +C D R Sbjct: 199 CASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECC-HGDLLECADDRA 257 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYV--EPTNDEI 144 L+ C++ + ECC K LE+ C+A ++ P+ P + ++ Sbjct: 258 D-LAKYICDNQD--TISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDV 314 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ +++ + F++EYS + + +S+L+ K Y + + CC P C+ Sbjct: 315 CKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFD 374 Query: 205 QLKHLS-LLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 +LKHL L + C Q+ GE + + +++ +KVP ++ ++ + + + Sbjct: 375 KLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGT 434 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 +CC ES C L +LC + + K CC E + ++ C + Sbjct: 435 RCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTE-SLVNRRPCFSALTPD 493 Query: 319 QLPELPDVE---LPTNKDVC---DPGNTKVMDKYTFELSRRTHLP-EVFLSKVLEPTLKS 371 + + + D+C D EL + E L V+E + Sbjct: 494 ETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAF 553 Query: 372 LGECCDVEDSTTCFNAKGPLLKKELSSFI 400 + +CC +D CF +GP L + + Sbjct: 554 VDKCCAADDKEACFAVEGPKLVVSTQTAL 582 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 77/450 (17%), Positives = 145/450 (32%), Gaps = 31/450 (6%) Query: 26 NKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYD 85 N +C EF ++ F L +R+ P ++ + + + CC C Sbjct: 120 NTLCDEFK-ADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLL 178 Query: 86 TRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEIC 145 + + K S++ ++ ER L ++ Q+FP ++ Sbjct: 179 PKIETMREKVLTSSARQ----RLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLV 234 Query: 146 EAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSA--SPTVCFLK-E 202 K KE + + E + + + + S + CC + C + E Sbjct: 235 TDLTKVHKECCHGDLLECADDRADL-AKYICDNQDTISSKLKECCDKPLLEKSHCIAEVE 293 Query: 203 RLQLKH----LSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDI 258 + + L+ VC Y + S L + +++ P + +L LA++ Sbjct: 294 KDAIPENLPPLTADFAEDKDVCKNYQE-AKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEY 352 Query: 259 TNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 L +CC + + L D + C + + + + Sbjct: 353 EATLEECCAKDDPHACYSTVFDKLKHLVDEPQNL---IKQNCDQFEKLGEYGFQNALIVR 409 Query: 319 QLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLE---------PTL 369 ++P V PT +V T S R E +LS +L P Sbjct: 410 YTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVS 469 Query: 370 KSLGECCDVE--DSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYK---KKLAE 424 + + +CC + CF+A P +F +K AD TE + + Sbjct: 470 EKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALV 529 Query: 425 RLKAKLPDATPTELAKLVNKHSDFASNCCS 454 L P AT +L ++ F CC+ Sbjct: 530 ELLKHKPKATEEQLKTVMENFVAFVDKCCA 559 >4F5V-A nrPDB Length = 584 Score = 547 bits (1408), Expect = e-156, Method: Composition-based stats. Identities = 108/445 (24%), Positives = 200/445 (44%), Gaps = 18/445 (4%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 + K+++ F+ +G+E F L L+ +S+ +E+ ++LVKEV L +AC A+ + Sbjct: 1 EAHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAA 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 +C + K C S + A+CC K+ ER C K + P + P Sbjct: 61 NCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEA 120 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D +C+AF D K + +++E + + L+ Y + Y +++ CC +A C Sbjct: 121 DVLCKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTP 180 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + LK +L++ R+ C+ +G++ + L++L+Q+ P AD D+ + D+T Sbjct: 181 KLDALKEKALISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTK 240 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +C++ T +S ++CC +K ++ C Y + + Sbjct: 241 VHKECCHGDLLEC-ADDRADLAKYMCEHQETISSHLKECC-DKPILEKAHCIYGLHNDET 298 Query: 321 PE-LPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVFLSKVL-EPTLKSLG 373 P LP V E +KDVC + + K+ +E SRR V L L + +L Sbjct: 299 PAGLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLK 358 Query: 374 ECCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CADYSENTFTEYKKKLAERLKAK 429 +CC +D C+ + E +D+ + L C Y + ++ L R K Sbjct: 359 KCCATDDPHACYA----KVLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKK 414 Query: 430 LPDATPTELAKLVNKHSDFASNCCS 454 +P + L ++ S CC Sbjct: 415 VPQVSTPTLVEISRSLGKVGSKCCK 439 Score = 158 bits (400), Expect = 4e-39, Method: Composition-based stats. Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 6/191 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C+ + LG +F + LV Y++K P + + ++ + + + CC E C + Sbjct: 392 CELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVED 451 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAAL----KHQPQEFPTYVEPTND 142 S + + C + PV +CC++ ++R+ C +AL + P+EF + Sbjct: 452 YLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKEFNAETFTFHA 511 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 +IC + K + E + A L + + +++ CC++ CF E Sbjct: 512 DICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSAEDKEACFAVE 571 Query: 203 RLQLKHLSLLT 213 +L S T Sbjct: 572 GPKLVESSKAT 582 Score = 143 bits (361), Expect = 2e-34, Method: Composition-based stats. Identities = 86/389 (22%), Positives = 155/389 (39%), Gaps = 22/389 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C G + + +LV S++FP F +S++V ++ + + CC G +C D R Sbjct: 200 CASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECC-HGDLLECADDRA 258 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCM--AALKHQPQEFPTYVEPTNDE--I 144 L+ CE H ECC K LE+ C+ P P E ++ + Sbjct: 259 D-LAKYMCEHQETISSH--LKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDV 315 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ + + + +F++EYS + + LL+ K+Y + + CC + P C+ K Sbjct: 316 CKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLD 375 Query: 205 QLKHLS-LLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 + + L L + C Y G+ + + L++ +KVP ++ ++ + + S Sbjct: 376 EFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGS 435 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 KCC E+ C+ L +LC + + K CC E + +D C + Sbjct: 436 KCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSE-SLVDRRPCFSALGPD 494 Query: 319 QL---PELPDVELPTNKDVC---DPGNTKVMDKYTFELSR-RTHLPEVFLSKVLEPTLKS 371 + E + D+C + EL + + H L V+ Sbjct: 495 ETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTAL 554 Query: 372 LGECCDVEDSTTCFNAKGPLLKKELSSFI 400 L +CC ED CF +GP L + + + Sbjct: 555 LDKCCSAEDKEACFAVEGPKLVESSKATL 583 >5HOZ-A nrPDB Length = 583 Score = 538 bits (1385), Expect = e-153, Method: Composition-based stats. Identities = 102/445 (22%), Positives = 192/445 (43%), Gaps = 17/445 (3%) Query: 22 DYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADP 81 D K+++ F+ LG++ F L LV +S+ FE +LV EV + C A+ + Sbjct: 1 DTHKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAE 60 Query: 82 DCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTN 141 +C + + K C + + A+CC K+ ER C K P ++P Sbjct: 61 NCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPK-LKPEP 119 Query: 142 DEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLK 201 D C AF++DP ++ ++++E + + L+ + + Y + CC + C + Sbjct: 120 DAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIP 179 Query: 202 ERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITN 260 + LK LL++ R+ CS + +GE+ + ++ +L+QK P AD +V + D+T Sbjct: 180 KLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTK 239 Query: 261 ILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL 320 + +CC +C A + + +C++ + + K + CC +K + C + L Sbjct: 240 VHKECCHGDLLEC-ADDRADLAKYICEHQDSISGKLKACC-DKPLLQKSHCIAEVKEDDL 297 Query: 321 P-ELPDV--ELPTNKDVC---DPGNTKVMDKYTFELSRRTHLPEVF-LSKVLEPTLKSLG 373 P +LP + + +K++C + + +E SRR V L ++ + +L Sbjct: 298 PSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLE 357 Query: 374 ECCDVEDSTTCFNAKGPLLK---KELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKL 430 +CC D C+ +E S + K +L + E F + L R K Sbjct: 358 KCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDF---QNALIVRYTKKA 414 Query: 431 PDATPTELAKLVNKHSDFASNCCSI 455 P + L ++ S CC + Sbjct: 415 PQVSTPTLVEIGRTLGKVGSRCCKL 439 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 40/186 (21%), Positives = 77/186 (41%), Gaps = 6/186 (3%) Query: 27 KVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCY 84 K C F +G+ DF + +V Y++K P + + ++ + + + CC E C Sbjct: 389 KNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCS 448 Query: 85 DTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPT 140 + + + C + PV +CCT ER+ C +AL+ + P+EF Sbjct: 449 ENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTF 508 Query: 141 NDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFL 200 + +IC + + + E + +A L + ++ + V CC + CF Sbjct: 509 HADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFA 568 Query: 201 KERLQL 206 +E +L Sbjct: 569 EEGPKL 574 Score = 142 bits (358), Expect = 3e-34, Method: Composition-based stats. Identities = 86/381 (22%), Positives = 152/381 (39%), Gaps = 22/381 (5%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88 C F + G+ + S+ S+KFP F +VS++V ++ + + CC G +C D R Sbjct: 199 CSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECC-HGDLLECADDRA 257 Query: 89 SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPTYV--EPTNDEI 144 L+ CE + CC K L++ C+A +K P + P + EI Sbjct: 258 D-LAKYICEHQD--SISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEI 314 Query: 145 CEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERL 204 C+ ++ + F++EYS + +SLL+ K+Y + + CC A P C+ Sbjct: 315 CKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFD 374 Query: 205 QLKHLSLL-TTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILS 263 Q L +L + C + GE + + +++ +K P ++ + + + S Sbjct: 375 QFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGS 434 Query: 264 KCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 +CC ES C L +LC + + K CC + + + C + Sbjct: 435 RCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTD-SLAERRPCFSALELD 493 Query: 319 Q--LP-ELPDVELPTNKDVC---DPGNTKVMDKYTFELSRRTHLP-EVFLSKVLEPTLKS 371 + +P E + D+C + EL + + L VL Sbjct: 494 EGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAF 553 Query: 372 LGECCDVEDSTTCFNAKGPLL 392 + +CC ED CF +GP L Sbjct: 554 VAKCCGAEDKEACFAEEGPKL 574 >6FAK-A nrPDB Length = 586 Score = 480 bits (1235), Expect = e-136, Method: Composition-based stats. Identities = 91/445 (20%), Positives = 184/445 (41%), Gaps = 15/445 (3%) Query: 21 RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGAD 80 RD E ++F +++ ++++ +++ TFE++ +LVK++V + C A+ Sbjct: 6 RDIENFNSTQKFI---EDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTL 62 Query: 81 PDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEF-PTYVEP 139 P+C + L K C + P + CC+K +R+LC K F P + Sbjct: 63 PECSKLPNNVLQEKIC-AMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTL 121 Query: 140 TNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCF 199 +E C+A+ + + N F++E + L++ + + SCC + C Sbjct: 122 DPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCL 181 Query: 200 LKERLQL-KHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDI 258 + + ++L ++ VC +G K + L+QK P + ++++ L ED+ Sbjct: 182 QTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDV 241 Query: 259 TNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318 ++ CCE C+ ++ + +C + +SK ++CC++K + C Sbjct: 242 SSNYDGCCEGDVVQCI-RDTSKVMNHICSKQDSISSKIKECCEKKIP-ERGQCIINSNKD 299 Query: 319 QLPE---LPDVELPTNKDVCDP---GNTKVMDKYTFELSRRTHLPEV-FLSKVLEPTLKS 371 P+ L + + +++VC K+TFE SRR + L ++++ Sbjct: 300 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDL 359 Query: 372 LGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLP 431 L CC+ E+ C+ + + Q+ C + K RL P Sbjct: 360 LRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAP 419 Query: 432 DATPTELAKLVNKHSDFASNCCSIN 456 + EL L K + CC+++ Sbjct: 420 QLSTEELVSLGEKMVTAFTTCCTLS 444 Score = 146 bits (369), Expect = 2e-35, Method: Composition-based stats. Identities = 82/405 (20%), Positives = 158/405 (39%), Gaps = 21/405 (5%) Query: 10 AVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVS 69 A+ L+ Y+K VC G + + + + S+KFP F+++ LV++V S Sbjct: 185 AIPVTQYLKAFSSYQK-HVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSS 243 Query: 70 LTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMA-ALKH 128 + CC EG C TS + C + ECC K+ ER C+ + K Sbjct: 244 NYDGCC-EGDVVQCIRD-TSKVMNHICSKQD--SISSKIKECCEKKIPERGQCIINSNKD 299 Query: 129 QPQE---FPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSM 185 + ++ +C+ DP + +F +EYS + + L+ + Y + Sbjct: 300 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDL 359 Query: 186 VGSCCTSASPTVCFLKERLQLKHLSLLT-TLSNRVCSQYAAYGEKKSRLSNLIKLAQKVP 244 + +CC + +P C+ + + + + + C + G+ + LI+L + P Sbjct: 360 LRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAP 419 Query: 245 TADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHT-VKLC--DNLSTKNSKFEDCCQ 301 E+++ L E + + CC + E L + +LC + T N + CC+ Sbjct: 420 QLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCK 479 Query: 302 EKTAMDVFVCTYFMPAAQLPELPDVE---LPTNKDVCDPGNTKV---MDKYTFELSR-RT 354 A C + A + P + D+C N ++ D++ L + + Sbjct: 480 TNFAFRRP-CFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKH 538 Query: 355 HLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSF 399 L + L + + +CC E CFN + P + + + Sbjct: 539 ELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGNKGENL 583 Score = 31.7 bits (70), Expect = 0.83, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 31/94 (32%), Gaps = 7/94 (7%) Query: 372 LGECCDVEDSTTCFNAKGPLLKKELSSF------IDKGQELCADYSENTFTEYKKKLAER 425 + ECC+ + + +C + + + K Sbjct: 278 IKECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQE-RDADPDTFFAKFTFE 336 Query: 426 LKAKLPDATPTELAKLVNKHSDFASNCCSINSPP 459 + PD + EL ++V + D NCC+ +PP Sbjct: 337 YSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPP 370 >1YSX-A nrPDB Length = 201 Score = 178 bits (451), Expect = 5e-45, Method: Composition-based stats. Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 6/184 (3%) Query: 29 CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCA--EGADPDCYDT 86 C+ F LG+ F + LV Y++K P + + ++ + + + CC E C + Sbjct: 8 CELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAED 67 Query: 87 RTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALK----HQPQEFPTYVEPTND 142 S + + C + PV +CCT+ + R+ C +AL+ + P+EF + Sbjct: 68 YLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHA 127 Query: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202 +IC K+ + + E + +A L + + + V CC + CF +E Sbjct: 128 DICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE 187 Query: 203 RLQL 206 +L Sbjct: 188 GKKL 191 Score = 71.7 bits (174), Expect = 6e-13, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 20/58 (34%), Gaps = 3/58 (5%) Query: 397 SSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCS 454 + I + EL E F + L R K+P + L ++ S CC Sbjct: 1 QNLIKQNCELFEQLGEYKF---QNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCK 55 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 70/185 (37%), Gaps = 13/185 (7%) Query: 220 CSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCC---ESASEDCMAK 276 C + GE K + + L++ +KVP ++ ++ ++ + SKCC E+ C Sbjct: 8 CELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAED 67 Query: 277 ELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQL---PELPDVELPTN 331 L +LC + + + CC E + ++ C + + E + Sbjct: 68 YLSVVLNQLCVLHEKTPVSDRVTKCCTE-SLVNRRPCFSALEVDETYVPKEFNAETFTFH 126 Query: 332 KDVC---DPGNTKVMDKYTFELSRRTHLP-EVFLSKVLEPTLKSLGECCDVEDSTTCFNA 387 D+C + EL + + L V++ + +CC +D TCF Sbjct: 127 ADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAE 186 Query: 388 KGPLL 392 +G L Sbjct: 187 EGKKL 191 >6O85-E nrPDB Length = 523 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 26/69 (37%), Gaps = 6/69 (8%) Query: 375 CCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL-CADYSENTFTEYKKKLAERLKAKLPDA 433 CC+ C + +S+ +D +L C ++ + RL + D Sbjct: 437 CCETYK--FCERVQTDAF---VSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDV 491 Query: 434 TPTELAKLV 442 TP EL LV Sbjct: 492 TPPELVDLV 500 >3UX1-A nrPDB Length = 518 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 21/71 (29%), Gaps = 10/71 (14%) Query: 124 AALKHQPQEFPTYVEPTNDEICEAFRKDP-KEYANQFM---------WEYSTNYGQAPLS 173 +KH P + P + AF KD + Q+ WE + Sbjct: 420 FGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVEIEWELQKENSKRWNP 479 Query: 174 LLVSYTKSYLS 184 + + Y S Sbjct: 480 EIQYTSNYYKS 490 >3Q5I-A nrPDB Length = 504 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 6/48 (12%), Positives = 20/48 (41%) Query: 327 ELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGE 374 + K++ D + T++ ++R E S+ ++ ++ + Sbjct: 267 DFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRWIKKYANNINK 314 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.127 0.342 Lambda K H 0.267 0.0382 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,135,107 Number of Sequences: 36641 Number of extensions: 590127 Number of successful extensions: 2149 Number of sequences better than 10.0: 18 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1751 Number of HSP's gapped (non-prelim): 99 length of query: 474 length of database: 10,336,785 effective HSP length: 101 effective length of query: 373 effective length of database: 6,636,044 effective search space: 2475244412 effective search space used: 2475244412 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)