BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P02749 (345 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1C1Z-A nrPDB 671 0.0 5FOB-C nrPDB 92 4e-19 2GSX-A nrPDB 72 3e-13 3ERB-A nrPDB 59 2e-09 2OK5-A nrPDB 57 1e-08 4C16-A nrPDB 57 2e-08 4J1Y-A nrPDB 45 4e-05 5UBM-B nrPDB 45 4e-05 4LOT-A nrPDB 44 1e-04 6H03-D nrPDB 42 3e-04 4KKD-A nrPDB 40 0.001 4FXG-G nrPDB 40 0.001 2QY0-A nrPDB 40 0.001 1ZJK-A nrPDB 39 0.002 1GPZ-A nrPDB 39 0.002 4IGD-A nrPDB 38 0.008 4AQB-A nrPDB 33 0.16 4A5W-B nrPDB 33 0.19 3EZ4-A nrPDB 32 0.45 2COZ-A nrPDB 30 1.0 >1C1Z-A nrPDB Length = 326 Score = 671 bits (1732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/326 (99%), Positives = 326/326 (100%) Query: 20 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC 79 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC Sbjct: 1 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC 60 Query: 80 TPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139 TPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP Sbjct: 61 TPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 120 Query: 140 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE 199 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE Sbjct: 121 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE 180 Query: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS 259 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS Sbjct: 181 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS 240 Query: 260 CKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGT 319 CKASCK+PVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGT Sbjct: 241 CKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGT 300 Query: 320 IEVPKCFKEHSSLAFWKTDASDVKPC 345 IEVPKCFKEHSSLAFWKTDASDVKPC Sbjct: 301 IEVPKCFKEHSSLAFWKTDASDVKPC 326 >5FOB-C nrPDB Length = 245 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 68/225 (30%), Positives = 106/225 (47%), Gaps = 19/225 (8%) Query: 25 KPDDLPFSTVVP--LKTFYEPGEEITYSCKPGYV-SRGGMRKFICPLTGLWPINTLKCTP 81 +P ++ F V Y G+ I Y C PGY + G C TG N +C Sbjct: 8 RPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFN--QCIK 65 Query: 82 RVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKC----TEEGKWSPELPVC 137 R CP ++NG + ++ ++I++SCN+G+YL G + C T W+P+ P+C Sbjct: 66 RRCPSPRDIDNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPIC 125 Query: 138 APIICPPPSIPTFATLRVYKPSAGNNSLYRDTAV--FECLPQHAMFGNDTITCTTHGNWT 195 + C P P+ + R G N Y D +V + C +++ GN + C+ G W+ Sbjct: 126 ESVKCQLP--PSISNGR----HNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSG-GEWS 178 Query: 196 KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL 240 P C+ VKCP P+ NG+++ K + Y D F C GY L Sbjct: 179 NPPTCQIVKCPHPTIL-NGYLSSGFKRSYSYNDNVDFTCKYGYKL 222 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 36/103 (34%), Positives = 49/103 (47%), Gaps = 9/103 (8%) Query: 40 FYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCP----FAGILENGAV 95 FY G +TYSC GY S G +C G W N C CP G L +G Sbjct: 147 FYTDGSVVTYSCNSGY-SLIGNSGVLCS-GGEWS-NPPTCQIVKCPHPTILNGYLSSGFK 203 Query: 96 RYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCA 138 R ++ Y + + F+C G+ L+G+ S+ C+ W PELP C Sbjct: 204 R--SYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCV 244 >2GSX-A nrPDB Length = 951 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 57/231 (24%), Positives = 94/231 (40%), Gaps = 28/231 (12%) Query: 44 GEEITYSCKPGYVSRGGMRKFICPLT----GLWPINTLKC--TPRV--CPFAGILENGAV 95 G E++Y C G+ G +K C G W + +C +P V CP + + Sbjct: 721 GNEVSYECDQGFYLLG-EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKL 779 Query: 96 R--YTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVC---APIICPPP----- 145 ++ + + + + CN GF +NG+ +C + W P +P C A I CPPP Sbjct: 780 NKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPN 839 Query: 146 SIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTK-LPECREVK 204 T + + P + ++ C + + G + CT G W++ P C+EV Sbjct: 840 GNHTGGNIARFSPGM--------SILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 891 Query: 205 CPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS 255 C P+ D + Y T C DGY L+G + +C W+ Sbjct: 892 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 942 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 78/300 (26%), Positives = 118/300 (39%), Gaps = 31/300 (10%) Query: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW-PINTLKCT 80 +CP+P +P + T Y G+ +T++CK + S G + C +W P C Sbjct: 70 SCPEPI-VPGGYKIRGSTPYRHGDSVTFACKTNF-SMNGNKSVWCQANNMWGPTRLPTCV 127 Query: 81 ---PRVCPFAGILENG---AVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPEL 134 P CP ++ NG + + ++++SC +G+ L G C GKWS Sbjct: 128 SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVP 187 Query: 135 PVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGN- 193 P C C S+ F +V +P + TA F C + + G + C G Sbjct: 188 PTCEEARC--KSLGRFPNGKVKEPPILRVGV---TANFFCDEGYRLQGPPSSRCVIAGQG 242 Query: 194 --WTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHD------GYSLDGPEE 245 WTK+P C E+ CP P NG + + Y T+ C + L G Sbjct: 243 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 302 Query: 246 IECT----KLGNWSA-MPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC 300 + CT K G WS P C+ S + +G V Q K+ + D V F C Sbjct: 303 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQ---KDRYTYNDTVIFAC 359 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 78/342 (22%), Positives = 128/342 (37%), Gaps = 76/342 (22%) Query: 14 CHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWP 73 C ++ + CP P L V K Y + + ++C G+ +G ++ C G W Sbjct: 322 CELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS-KQIRCNAQGTWE 380 Query: 74 INTLKCTPRVCPFAGILENGA---VRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKW 130 + C + C + NG F+ +I +SCN G+ L G +S +CT EG W Sbjct: 381 PSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 439 Query: 131 SPELPVCAPIICPPP-------------------------------------SIPTFATL 153 +P +P C C +IP F + Sbjct: 440 TPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEI 499 Query: 154 R------------VYKPSAGNNSL----YRDTAVFECLP------QHAMFGNDTITCTTH 191 R +Y + +SL Y T + C P + ++ G TI CT++ Sbjct: 500 RLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 559 Query: 192 ----GNWTK-LPECR----EVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDG 242 G W+ P C+ V+C NG+ + +Y D TF C+ G++L G Sbjct: 560 DQERGTWSGPAPLCKLSLLAVQCSH-VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 618 Query: 243 PEEIECTKLGNWS-AMPSC-KASCKVPVKKATVVYQGERVKI 282 +I C W +P C K +C+ + + G RV++ Sbjct: 619 SSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL 660 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 59/244 (24%), Positives = 95/244 (38%), Gaps = 34/244 (13%) Query: 44 GEEITYSCKPGYVSRGGMRKFICPLT----------GLW----PINTLKCTPRVCPFAGI 89 G +TY+C PG RG I T G W P+ L C I Sbjct: 529 GTTVTYTCNPG-PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHI 587 Query: 90 LENGAV--RYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSI 147 + + + Y +T++F C +GF L G+ +C + W PE+PVC C Sbjct: 588 ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC----- 642 Query: 148 PTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITC--TTHGNW-TKLPECREVK 204 + + AG+ +T+ C + + G+ C +G W K+P C+ + Sbjct: 643 -QHVRQSLQELPAGSRVELVNTS---CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 698 Query: 205 CPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTK----LGNWSA-MPS 259 C P NG Y ++ ++ C G+ L G ++++C G+WS P Sbjct: 699 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 758 Query: 260 CKAS 263 C S Sbjct: 759 CLRS 762 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 66/188 (35%), Gaps = 15/188 (7%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82 CP P+ + + Y + + C PG++ G R C W C + Sbjct: 768 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGS-RVIRCHTDNTWVPGVPTCIKK 826 Query: 83 V---CPFAGILENG---AVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPV 136 CP NG F +I +SC+ G+ L G CT EG WS P Sbjct: 827 AFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPH 886 Query: 137 CAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAV--FECLPQHAMFGNDTITCTTHGNW 194 C + C P A + + +Y+ AV EC + + G+ C + W Sbjct: 887 CKEVNCSSP-----ADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW 941 Query: 195 T-KLPECR 201 L CR Sbjct: 942 NPPLAVCR 949 >3ERB-A nrPDB Length = 223 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 52/193 (26%), Positives = 75/193 (38%), Gaps = 21/193 (10%) Query: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW-------PI 74 +CP+ ++ T L + PG +TYSC G R +C +G W + Sbjct: 3 SCPQNVNISGGTFT-LSHGWAPGSLLTYSCPQGLYPSPASR--LCKSSGQWQTPGATRSL 59 Query: 75 NTLKCTPRVCPFAGILENGAV--RYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSP 132 + C P CP ENG R ++ +SF C GF L G+ +C G W Sbjct: 60 SKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDG 119 Query: 133 ELPVC--APIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTT 190 E VC CP P I A ++ G+ YR C + G+ C Sbjct: 120 ETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYR------CSSNLVLTGSSERECQG 173 Query: 191 HGNWTKL-PECRE 202 +G W+ P CR+ Sbjct: 174 NGVWSGTEPICRQ 186 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 46/170 (27%), Positives = 69/170 (40%), Gaps = 25/170 (14%) Query: 106 ISFSCNTGFYLNGADSAKCTEEGKW-------SPELPVCAPIICPPPSIPTFATLRVYKP 158 +++SC G Y + A S C G+W S VC P+ CP P +F +Y P Sbjct: 27 LTYSCPQGLYPSPA-SRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPV--SFEN-GIYTP 82 Query: 159 SAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW---TKLPECREVKCPFPSRPDNGF 215 G+ + + + FEC + G+ C +G W T + + CP P Sbjct: 83 RLGSYPVGGNVS-FECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG------ 135 Query: 216 VNYPAKPTLY---YKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-PSCK 261 ++ A T + + DK + C L G E EC G WS P C+ Sbjct: 136 ISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 185 >2OK5-A nrPDB Length = 752 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 3/117 (2%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82 CP+P D P +Y +EI++ C GY RG + C + G W T C Sbjct: 88 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANR-TCQVNGRWSGQTAICDNG 146 Query: 83 V--CPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVC 137 C GI + + +++++ C+ G L G+ C E G WS P C Sbjct: 147 AGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 203 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 11/83 (13%) Query: 185 TITCTTHGNWTKL----------PECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGC 234 T TC + G+W+ L ECR + CP P +NG +P P D+ +F C Sbjct: 58 TRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY-WPRSPYYNVSDEISFHC 116 Query: 235 HDGYSLDGPEEIECTKLGNWSAM 257 +DGY+L G C G WS Sbjct: 117 YDGYTLRGSANRTCQVNGRWSGQ 139 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 44/191 (23%), Positives = 68/191 (35%), Gaps = 17/191 (8%) Query: 84 CPFAGI-LENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSP---------E 133 C G+ ++ G+ R + + + C +GFY + C G WS Sbjct: 22 CSLEGVEIKGGSFRL--LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVR 79 Query: 134 LPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGN 193 C I CP P F + S N D F C + + G+ TC +G Sbjct: 80 KAECRAIHCPRPH--DFENGEYWPRSPYYN--VSDEISFHCYDGYTLRGSANRTCQVNGR 135 Query: 194 WTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGN 253 W+ + + S P +D T+ C G +L G + C + G+ Sbjct: 136 WSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS 195 Query: 254 WSAM-PSCKAS 263 WS PSC+ S Sbjct: 196 WSGTEPSCQDS 206 >4C16-A nrPDB Length = 280 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 6/130 (4%) Query: 137 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT 195 C I+ C P +L P GN S Y + C + +T+ C + G W+ Sbjct: 153 CEQIVNCTALESPEHGSLVCSHP-LGNFS-YNSSCSISCDRGYLPSSMETMQCMSSGEWS 210 Query: 196 K-LPECREVKCPFPSRPDNGFVNYPAKPTLY-YKDKATFGCHDGYSLDGPEEIECTKLGN 253 +P C V+C + P NGFV P + + TF C +G+ L G + ++CT GN Sbjct: 211 APIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN 270 Query: 254 W-SAMPSCKA 262 W + P+CKA Sbjct: 271 WDNEKPTCKA 280 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Query: 99 TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKP 158 F Y ++ S SC+ G+ + ++ +C G+WS +P C + C + P + ++ Sbjct: 178 NFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQN 237 Query: 159 SAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW-TKLPECR 201 + + T F+C + G ++ CT+ GNW + P C+ Sbjct: 238 PG--SFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 279 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 8/134 (5%) Query: 9 FSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPL 68 FS C + P+ PL F + SC GY+ M C Sbjct: 148 FSGLKCEQIVNCTALESPEHGSLVCSHPLGNF-SYNSSCSISCDRGYLP-SSMETMQCMS 205 Query: 69 TGLW--PI---NTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAK 123 +G W PI N ++C P G +E +F + T +F C GF L GA S + Sbjct: 206 SGEWSAPIPACNVVECDAVTNPANGFVE-CFQNPGSFPWNTTCTFDCEEGFELMGAQSLQ 264 Query: 124 CTEEGKWSPELPVC 137 CT G W E P C Sbjct: 265 CTSSGNWDNEKPTC 278 >4J1Y-A nrPDB Length = 397 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 16/140 (11%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV---SRGGMRKF--ICPLTGLWPINTL 77 CPK +D P S P K Y + + +C G+ R G F C G W + L Sbjct: 3 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 61 Query: 78 KCTPRVCPFAGILENGAVRY-TTFEYPNTISFSCNTGFYL---NGADSAKCTEEGKW--- 130 KC P C +ENG V + + + I ++C +Y G C G W Sbjct: 62 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNE 121 Query: 131 --SPELPVCAPIICPPPSIP 148 PELP C P +C P P Sbjct: 122 VLGPELPKCVP-VCGVPREP 140 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 34/142 (23%), Positives = 51/142 (35%), Gaps = 23/142 (16%) Query: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHGNWT 195 CP P V++P A ++RD CL + TC ++G W+ Sbjct: 3 CPKEDTPN----SVWEP-AKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 57 Query: 196 KLP-ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGY---SLDGPEEIECTKL 251 +C+ V C P +NG V P + + + C + Y G E C Sbjct: 58 NSKLKCQPVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYHCAGN 115 Query: 252 GNWS------AMPSCKASCKVP 267 G+W +P C C VP Sbjct: 116 GSWVNEVLGPELPKCVPVCGVP 137 >5UBM-B nrPDB Length = 152 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 15/132 (11%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV---SRGGMRKF--ICPLTGLWPINTL 77 CPK +D P S P K Y + + +C G+ R G F C G W + L Sbjct: 10 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 68 Query: 78 KCTPRVCPFAGILENGAVRY-TTFEYPNTISFSCNTGFYL---NGADSAKCTEEGKW--- 130 KC P C +ENG V + + + I ++C +Y G C G W Sbjct: 69 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNE 128 Query: 131 --SPELPVCAPI 140 PELP C P+ Sbjct: 129 VLGPELPKCVPV 140 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 35/145 (24%), Positives = 53/145 (36%), Gaps = 23/145 (15%) Query: 139 PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHG 192 P+ CP P V++P A ++RD CL + TC ++G Sbjct: 7 PMPCPKEDTPN----SVWEP-AKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 61 Query: 193 NWTKLP-ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL---DGPEEIEC 248 W+ +C+ V C P +NG V P + + + C + Y G E C Sbjct: 62 KWSNSKLKCQPVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYHC 119 Query: 249 TKLGNWS------AMPSCKASCKVP 267 G+W +P C C VP Sbjct: 120 AGNGSWVNEVLGPELPKCVPVCGVP 144 >4LOT-A nrPDB Length = 249 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 15/131 (11%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV---SRGGMRKF--ICPLTGLWPINTL 77 CPK +D P S P K Y + + +C G+ R G F C G W + L Sbjct: 120 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 178 Query: 78 KCTPRVCPFAGILENGAVRY-TTFEYPNTISFSCNTGFYL---NGADSAKCTEEGKW--- 130 KC P C +ENG V + + + I ++C +Y G C G W Sbjct: 179 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNE 238 Query: 131 --SPELPVCAP 139 PELP C P Sbjct: 239 VLGPELPKCVP 249 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 30/126 (23%), Positives = 47/126 (37%), Gaps = 17/126 (13%) Query: 139 PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHG 192 P+ CP P V++P A ++RD CL + TC ++G Sbjct: 117 PMPCPKEDTPN----SVWEP-AKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 171 Query: 193 NWTKLP-ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL---DGPEEIEC 248 W+ +C+ V C P +NG V P + + + C + Y G E C Sbjct: 172 KWSNSKLKCQPVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYHC 229 Query: 249 TKLGNW 254 G+W Sbjct: 230 AGNGSW 235 >6H03-D nrPDB Length = 821 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 2/88 (2%) Query: 169 TAVFECLPQHAMFGNDTITCTTHGNW-TKLPECREVKCPFPSRPDNGFVNYPAKPTLYYK 227 V+ C +++ GN C W C+++ C P D G ++P KP Sbjct: 572 NVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMD-GIQSHPQKPFYTVG 630 Query: 228 DKATFGCHDGYSLDGPEEIECTKLGNWS 255 +K T C G SL+GP C WS Sbjct: 631 EKVTVSCSGGMSLEGPSAFLCGSSLKWS 658 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 5/115 (4%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82 CP P L V T + G+ + Y+C GY S G C W + + C Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGY-SLIGNPVARCGEDLRWLVGEMHCQKI 607 Query: 83 VCPFAGILENGAVRYTT---FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPEL 134 C +L +G + + ++ SC+ G L G + C KWSPE+ Sbjct: 608 ACVLP-VLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEM 661 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 31/132 (23%), Positives = 50/132 (37%), Gaps = 12/132 (9%) Query: 84 CPFAGILENGAVR--YTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141 CP L++G V+ T F + ++CN G+ L G A+C E+ +W C I Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIA 608 Query: 142 CPPPSIPTFATLRVYKP--SAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE 199 C P + KP + G + C ++ G C + W+ PE Sbjct: 609 CVLPVLMDGIQSHPQKPFYTVG------EKVTVSCSGGMSLEGPSAFLCGSSLKWS--PE 660 Query: 200 CREVKCPFPSRP 211 + +C P Sbjct: 661 MKNARCVQKENP 672 >4KKD-A nrPDB Length = 433 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/165 (23%), Positives = 65/165 (39%), Gaps = 34/165 (20%) Query: 85 PFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD------SAKCTEEGKWSPELPVCA 138 P G +E +Y + + + SC+TG+ + + +C ++G WS ++P C Sbjct: 12 PVHGKIEPSQAKYF---FKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK 68 Query: 139 PIICPPP-----SIPTFATLRVYKPSAGNNSLYRDTAVFECL-PQHAMFGNDT--ITCTT 190 + C P + TF+T N + Y+ + C P + M N+T TC+ Sbjct: 69 IVDCRAPGELEHGLITFST-------RNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSA 121 Query: 191 HGNWTK----------LPECREVKCPFPSRPDNGFVNYPAKPTLY 225 G W LPEC + PS A+P L+ Sbjct: 122 QGVWMNKVLGRSLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLF 166 Score = 35.4 bits (80), Expect = 0.039, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 9/72 (12%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL--DGPE----EIECTKLGNWS-A 256 +CP P +G + P++ ++KD+ C GY + D E +IEC K G WS Sbjct: 5 ECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 63 Query: 257 MPSCK-ASCKVP 267 +P+CK C+ P Sbjct: 64 IPTCKIVDCRAP 75 Score = 34.7 bits (78), Expect = 0.064, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 17/139 (12%) Query: 18 IAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGY-VSRGGMR----KFICPLTGLW 72 +AG CP+ + P + Y +++ SC GY V + + + C G W Sbjct: 1 MAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTW 60 Query: 73 PINTLKCTPRVCPFAGILENGAVRYTTFE----YPNTISFSCNTGFYL---NGADSAKCT 125 C C G LE+G + ++T Y + I +SC +Y N C+ Sbjct: 61 SNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCS 120 Query: 126 EEGKW-----SPELPVCAP 139 +G W LP C P Sbjct: 121 AQGVWMNKVLGRSLPTCLP 139 >4FXG-G nrPDB Length = 154 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 53/142 (37%), Gaps = 16/142 (11%) Query: 15 HVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG---MRKF--ICPLT 69 H CP P P V P++ Y + + C+ GY G ++ F +C Sbjct: 2 HYTSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKD 61 Query: 70 GLWPINTLKCTPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLNGADSAK-- 123 G W C+ C L +G V Y T Y I +SC FY + K Sbjct: 62 GSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYV 121 Query: 124 CTEEGKWSP-----ELPVCAPI 140 C +G W+ LPVC P+ Sbjct: 122 CEADGFWTSSKGEKSLPVCEPV 143 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 41/151 (27%), Positives = 57/151 (37%), Gaps = 19/151 (12%) Query: 80 TPRVCPFAGILENGAVRYTTFEYPNTISFS--CNTGFYLNGAD------SAKCTEEGKWS 131 T CP+ NG V +Y SFS C TG+ L +A C ++G W Sbjct: 6 TAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWD 65 Query: 132 PELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQ-HAMFGND-TITCT 189 +P C+ + C PP + RV + + Y+ + C + M ND C Sbjct: 66 RPMPACSIVDCGPPD--DLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCE 123 Query: 190 THGNWT------KLPECREVKCPFPSRPDNG 214 G WT LP C V C +R G Sbjct: 124 ADGFWTSSKGEKSLPVCEPV-CGLSARTTGG 153 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 8/63 (12%) Query: 205 CPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYS-LDGPEEIE-----CTKLGNWSA-M 257 CP+P P NG V+ P + KD + C GY L G ++ C K G+W M Sbjct: 10 CPYPMAPPNGHVS-PVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 68 Query: 258 PSC 260 P+C Sbjct: 69 PAC 71 >2QY0-A nrPDB Length = 159 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 60/158 (37%), Gaps = 25/158 (15%) Query: 21 RTCPKPDDL-PFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKF-----ICPLTGLWPI 74 + CP+P L F+ + L+ Y+ + +CK GY G + +C G W Sbjct: 3 QACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 62 Query: 75 NTLKCTPRVCPFAGILENGAVRYTTFEYPNT----ISFSCNTGFYLNGADSAK------- 123 +C + C L NG RYTT NT I + C+ +Y + Sbjct: 63 AMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGV 122 Query: 124 --CTEEGKWSPE-----LPVCAPIICPPPSIPTFATLR 154 CT +G W E +P C P +C P P R Sbjct: 123 YTCTAQGIWKNEQKGEKIPRCLP-VCGKPVNPVEQRQR 159 >1ZJK-A nrPDB Length = 403 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/148 (25%), Positives = 55/148 (37%), Gaps = 16/148 (10%) Query: 9 FSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG---MRKF- 64 + + H CP P P V P++ Y + + C+ GY G ++ F Sbjct: 3 MTGWKIHYTSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFT 62 Query: 65 -ICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLNGA 119 +C G W C+ C L +G V Y T Y I +SC FY Sbjct: 63 AVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKV 122 Query: 120 DSAK--CTEEGKWSP-----ELPVCAPI 140 + K C +G W+ LPVC P+ Sbjct: 123 NDGKYVCEADGFWTSSKGEKSLPVCEPV 150 Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust. Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 23/166 (13%) Query: 68 LTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFS--CNTGFYLNGAD----- 120 +TG W I+ T CP+ NG V +Y SFS C TG+ L Sbjct: 3 MTG-WKIH-YTSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKS 60 Query: 121 -SAKCTEEGKWSPELPVCAPIIC-PPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQ- 177 +A C ++G W +P C+ + C PP +P+ + P + Y+ + C Sbjct: 61 FTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGV---TTYKAVIQYSCEETF 117 Query: 178 HAMFGND-TITCTTHGNWT------KLPECREVKCPFPSRPDNGFV 216 + M ND C G WT LP C V C +R G + Sbjct: 118 YTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGQI 162 >1GPZ-A nrPDB Length = 399 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 25/151 (16%) Query: 23 CPKPDDL-PFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKF-----ICPLTGLWPINT 76 CP+P L F+ + L+ Y+ + +CK GY G + +C G W Sbjct: 3 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAM 62 Query: 77 LKCTPRVCPFAGILENGAVRYTTFEYPNT----ISFSCNTGFYLNGADSAK--------- 123 +C + C L NG RYTT NT I + C+ +Y + Sbjct: 63 PRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYT 122 Query: 124 CTEEGKWSPE-----LPVCAPIICPPPSIPT 149 CT +G W E +P C P +C P P Sbjct: 123 CTAQGIWKNEQKGEKIPRCLP-VCGKPVNPV 152 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 7/66 (10%) Query: 203 VKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL-DGPEEIE-----CTKLGNW-S 255 +KCP P D + +P ++D C GY L +G + + C G W Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 256 AMPSCK 261 AMP CK Sbjct: 61 AMPRCK 66 >4IGD-A nrPDB Length = 406 Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust. Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 31/144 (21%) Query: 85 PFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD------SAKCTEEGKWSPELPVCA 138 P G +E +Y + + + SC+TG+ + + +C ++G WS ++P C Sbjct: 14 PVHGKIEPSQAKYF---FKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK 70 Query: 139 PIICPPP-----SIPTFATLRVYKPSAGNNSLYRDTAVFECL-PQHAMFGNDT--ITCTT 190 + C P + TF+T N + Y+ + C P + M N+T TC+ Sbjct: 71 IVDCRAPGELEHGLITFST-------RNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSA 123 Query: 191 HGNWTK------LPECREVKCPFP 208 G W LP C V C P Sbjct: 124 QGVWMNKVLGRSLPTCLPV-CGLP 146 Score = 36.6 bits (83), Expect = 0.016, Method: Compositional matrix adjust. Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 17/120 (14%) Query: 165 LYRDTAVFECLPQHAMFGNDT------ITCTTHGNWT-KLPECREVKCPFPSRPDNGFVN 217 ++D + C + + ++ I C G W+ K+P C+ V C P ++G + Sbjct: 27 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLIT 86 Query: 218 YPAKPTL-YYKDKATFGCHDGY--SLDGPEEI-ECTKLGNW------SAMPSCKASCKVP 267 + + L YK + + C + Y L+ I C+ G W ++P+C C +P Sbjct: 87 FSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPVCGLP 146 Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust. Identities = 33/142 (23%), Positives = 54/142 (38%), Gaps = 17/142 (11%) Query: 16 VAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGY-VSRGGMR----KFICPLTG 70 ++ G CP+ + P + Y +++ SC GY V + + + C G Sbjct: 1 ASMTGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG 60 Query: 71 LWPINTLKCTPRVCPFAGILENGAVRYTTFE----YPNTISFSCNTGFYL---NGADSAK 123 W C C G LE+G + ++T Y + I +SC +Y N Sbjct: 61 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT 120 Query: 124 CTEEGKW-----SPELPVCAPI 140 C+ +G W LP C P+ Sbjct: 121 CSAQGVWMNKVLGRSLPTCLPV 142 Score = 35.0 bits (79), Expect = 0.049, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 9/72 (12%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL--DGPE----EIECTKLGNWS-A 256 +CP P +G + P++ ++KD+ C GY + D E +IEC K G WS Sbjct: 7 ECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 65 Query: 257 MPSCK-ASCKVP 267 +P+CK C+ P Sbjct: 66 IPTCKIVDCRAP 77 >4AQB-A nrPDB Length = 361 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 8/67 (11%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL--DGPE----EIECTKLGNWS-A 256 +CP P +G + P++ ++KD+ C GY + D E +IEC K G WS Sbjct: 281 ECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 339 Query: 257 MPSCKAS 263 +P+CK + Sbjct: 340 IPTCKKN 346 >4A5W-B nrPDB Length = 913 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 29/131 (22%), Positives = 50/131 (38%), Gaps = 6/131 (4%) Query: 19 AGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLK 78 A CP+P + K Y GE++ SC G+ + G + F C G W ++ Sbjct: 619 ADSGCPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETV-GYQYFRCLPDGTWRQGDVE 677 Query: 79 CTPRVCPFAGILENGAVR--YTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPV 136 C C + E + + +I +C GF + G C + W+P P+ Sbjct: 678 CQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTC-QGNSWTP--PI 734 Query: 137 CAPIICPPPSI 147 + C ++ Sbjct: 735 SNSLTCEKDTL 745 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 28/73 (38%), Gaps = 6/73 (8%) Query: 91 ENGAVRYTTFEY--PNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIP 148 ENG +R Y + SC TGF G +C +G W C C P + Sbjct: 630 ENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQ 689 Query: 149 TFATL----RVYK 157 T+ R+Y+ Sbjct: 690 EVLTITPFQRLYR 702 >3EZ4-A nrPDB Length = 269 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 11/77 (14%) Query: 107 SFSCNTGFYLNGADSAKCTEEGKWSPE---------LPVCAPIICPPPSIPTFATLRVY- 156 +F+ GA K E G+W E +PVCA + P S+ F +V Sbjct: 102 AFASAVKLMRAGAQMVKL-EGGEWLAETVRFLVERAVPVCAHVGLTPQSVHAFGGFKVQG 160 Query: 157 KPSAGNNSLYRDTAVFE 173 K AG L RD E Sbjct: 161 KTEAGAAQLLRDARAVE 177 >2COZ-A nrPDB Length = 122 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 150 FATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181 +A + + KP NN Y A FEC +H +F Sbjct: 61 WAGVELDKPEGNNNGTYDGIAYFECKEKHGIF 92 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1C1Z-A nrPDB 472 e-133 2GSX-A nrPDB 208 3e-54 5FOB-C nrPDB 191 3e-49 3ERB-A nrPDB 158 4e-39 2OK5-A nrPDB 141 4e-34 4J1Y-A nrPDB 138 4e-33 4FXG-G nrPDB 127 7e-30 2QY0-A nrPDB 125 2e-29 4LOT-A nrPDB 125 3e-29 5UBM-B nrPDB 124 5e-29 4KKD-A nrPDB 124 6e-29 4C16-A nrPDB 123 1e-28 6H03-D nrPDB 99 4e-21 Sequences not found previously or not previously below threshold: 1ZJK-A nrPDB 143 8e-35 1GPZ-A nrPDB 135 3e-32 4IGD-A nrPDB 107 8e-24 1ELV-A nrPDB 77 1e-14 1MD7-A nrPDB 73 2e-13 4A5W-B nrPDB 71 8e-13 4LOS-A nrPDB 69 2e-12 1Q3X-A nrPDB 68 6e-12 3TVJ-A nrPDB 58 5e-09 4AQB-A nrPDB 54 9e-08 1L6J-A nrPDB 38 0.008 4F4O-C nrPDB 36 0.024 1CK7-A nrPDB 33 0.23 1EAK-A nrPDB 32 0.46 3U2P-A nrPDB 32 0.49 6FO0-R nrPDB 31 0.59 3EHU-A nrPDB 31 1.1 5GUP-Ae nrPDB 30 1.5 3U9U-E nrPDB 30 1.6 5XWD-A nrPDB 29 2.4 3FL7-A nrPDB 29 3.0 5ZJI-N nrPDB 28 5.1 3MX0-A nrPDB 28 5.8 2GTH-A nrPDB 27 8.2 >1C1Z-A nrPDB Length = 326 Score = 472 bits (1213), Expect = e-133, Method: Composition-based stats. Identities = 325/326 (99%), Positives = 326/326 (100%) Query: 20 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC 79 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC Sbjct: 1 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC 60 Query: 80 TPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139 TPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP Sbjct: 61 TPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 120 Query: 140 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE 199 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE Sbjct: 121 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPE 180 Query: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS 259 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS Sbjct: 181 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS 240 Query: 260 CKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGT 319 CKASCK+PVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGT Sbjct: 241 CKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGT 300 Query: 320 IEVPKCFKEHSSLAFWKTDASDVKPC 345 IEVPKCFKEHSSLAFWKTDASDVKPC Sbjct: 301 IEVPKCFKEHSSLAFWKTDASDVKPC 326 >2GSX-A nrPDB Length = 951 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 98/251 (39%), Gaps = 28/251 (11%) Query: 24 PKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLT----GLWPINTLKC 79 P P + + + G E++Y C G+ G +K C G W + +C Sbjct: 701 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQC 759 Query: 80 --TPR--VCPFAGILENGAVR--YTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPE 133 +P CP + + ++ + + + + CN GF +NG+ +C + W P Sbjct: 760 LRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 819 Query: 134 LPVC---APIICPPP-----SIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT 185 +P C A I CPPP T + + P + ++ C + + G Sbjct: 820 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGM--------SILYSCDQGYLLVGEAL 871 Query: 186 ITCTTHGNWTKL-PECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPE 244 + CT G W++ P C+EV C P+ D + Y T C DGY L+G Sbjct: 872 LLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSP 931 Query: 245 EIECTKLGNWS 255 + +C W+ Sbjct: 932 QSQCQSDHQWN 942 Score = 177 bits (449), Expect = 5e-45, Method: Composition-based stats. Identities = 77/309 (24%), Positives = 114/309 (36%), Gaps = 31/309 (10%) Query: 13 LCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW 72 C +CP+P +P + T Y G+ +T++CK + S G + C +W Sbjct: 61 KCEYFNKYSSCPEPI-VPGGYKIRGSTPYRHGDSVTFACKTNF-SMNGNKSVWCQANNMW 118 Query: 73 -PINTLKCT---PRVCPFAGILENGA---VRYTTFEYPNTISFSCNTGFYLNGADSAKCT 125 P C P CP ++ NG + ++++SC +G+ L G C Sbjct: 119 GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 178 Query: 126 EEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT 185 GKWS P C C F +V +P TA F C + + G + Sbjct: 179 SSGKWSAVPPTCEEARCKSLGR--FPNGKVKEPPI---LRVGVTANFFCDEGYRLQGPPS 233 Query: 186 ITCTTHGN---WTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHD------ 236 C G WTK+P C E+ CP P NG + + Y T+ C Sbjct: 234 SRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGV 293 Query: 237 GYSLDGPEEIEC----TKLGNWSA-MPSCKASCKVPVKKATVVYQGERVKIQEKFKNGML 291 + L G + C K G WS P C+ S + +G V Q K+ Sbjct: 294 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQ---KDRYT 350 Query: 292 HGDKVSFFC 300 + D V F C Sbjct: 351 YNDTVIFAC 359 Score = 160 bits (405), Expect = 8e-40, Method: Composition-based stats. Identities = 73/303 (24%), Positives = 113/303 (37%), Gaps = 28/303 (9%) Query: 13 LCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW 72 C ++ + CP P L V K Y + + ++C G+ + G ++ C G W Sbjct: 321 RCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK-GSKQIRCNAQGTW 379 Query: 73 PINTLKCTPRVCPFAGILENGAVRY---TTFEYPNTISFSCNTGFYLNGADSAKCTEEGK 129 + C + C + NG F+ +I +SCN G+ L G +S +CT EG Sbjct: 380 EPSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 438 Query: 130 WSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCT 189 W+P +P C C + KP R C + + G+ C Sbjct: 439 WTPPVPQCKVAACEATG-----RQLLTKPQH---QFVRPDVNSSCGEGYKLSGSVYQECQ 490 Query: 190 THGNW-TKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDG------YSLDG 242 W ++ C+E+ CP P NG + Y T+ C+ G +SL G Sbjct: 491 GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 550 Query: 243 PEEIECTKL----GNWSA-MPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVS 297 I CT G WS P CK S + G ++ +E + D V+ Sbjct: 551 ESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP---YFYNDTVT 607 Query: 298 FFC 300 F C Sbjct: 608 FKC 610 Score = 133 bits (333), Expect = 2e-31, Method: Composition-based stats. Identities = 71/297 (23%), Positives = 112/297 (37%), Gaps = 31/297 (10%) Query: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFIC----PLTGLWPINTL 77 +C P + + T G I YSC + G + +C + G W Sbjct: 2 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLI-GEKSLLCITKDKVDGTWDKPAP 60 Query: 78 KC----TPRVCPFAGILENGAVRYTT-FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSP 132 KC CP + +R +T + + ++++F+C T F +NG S C W P Sbjct: 61 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 120 Query: 133 E-LPVCA---PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITC 188 LP C P+ C P++P + G+ + + + C + + G I C Sbjct: 121 TRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAP-GLSVTYSCESGYLLVGEKIINC 177 Query: 189 TTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIE 247 + G W+ P C E +C R NG V P P L A F C +GY L GP Sbjct: 178 LSSGKWSAVPPTCEEARCKSLGRFPNGKVKEP--PILRVGVTANFFCDEGYRLQGPPSSR 235 Query: 248 CTKLGN---WSAMPSCKASCKVPVKKA-TVVYQGERVKIQEKFKNGMLHGDKVSFFC 300 C G W+ MP C+ + + G + + +G V++ C Sbjct: 236 CVIAGQGVAWTKMPVCEE----IFCPSPPPILNGRHIGNSLA---NVSYGSIVTYTC 285 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 67/303 (22%), Positives = 103/303 (33%), Gaps = 36/303 (11%) Query: 22 TCPKPDDLPFSTVVPLK-TFYEPGEEITYSCKPGYV-----SRGGMRKFICPLT----GL 71 TCP P + + G +TY+C PG S G C G Sbjct: 506 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 565 Query: 72 WPINTLKCT----PRVCPFAGILENGAV--RYTTFEYPNTISFSCNTGFYLNGADSAKCT 125 W C C I + + + Y +T++F C +GF L G+ +C Sbjct: 566 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 625 Query: 126 EEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT 185 + W PE+PVC C + N C + + G+ Sbjct: 626 ADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNT---------SCQDGYQLTGHAY 676 Query: 186 ITCT--THGNW-TKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDG 242 C +G W K+P C+ + C P NG Y ++ ++ C G+ L G Sbjct: 677 QMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLG 736 Query: 243 PEEIECTKL----GNWSA-MPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVS 297 ++++C G+WS P C S V V G ++ K + H D V Sbjct: 737 EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN---KTHSAYSHNDIVY 793 Query: 298 FFC 300 C Sbjct: 794 VDC 796 Score = 95.7 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 43/196 (21%), Positives = 63/196 (32%), Gaps = 11/196 (5%) Query: 13 LCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW 72 C + CP P+ + + Y + + C PG++ G R C W Sbjct: 758 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM-NGSRVIRCHTDNTW 816 Query: 73 PINTLKCTPRV---CPFAGILENGAVRYTT---FEYPNTISFSCNTGFYLNGADSAKCTE 126 C + CP NG F +I +SC+ G+ L G CT Sbjct: 817 VPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH 876 Query: 127 EGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTI 186 EG WS P C + C P+ + Y EC + + G+ Sbjct: 877 EGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMY---QYGAVVTLECEDGYMLEGSPQS 933 Query: 187 TCTTHGNWT-KLPECR 201 C + W L CR Sbjct: 934 QCQSDHQWNPPLAVCR 949 Score = 87.2 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 44/121 (36%), Gaps = 5/121 (4%) Query: 23 CPKPDDLPFSTVVPLK-TFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81 CP P P + PG I YSC GY G +C G W C Sbjct: 831 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGY-LLVGEALLLCTHEGTWSQPAPHCKE 889 Query: 82 RVCPFAGILENGAVRYTT---FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCA 138 C ++ ++Y ++ C G+ L G+ ++C + +W+P L VC Sbjct: 890 VNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 949 Query: 139 P 139 Sbjct: 950 S 950 Score = 51.8 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 41/104 (39%), Gaps = 10/104 (9%) Query: 203 VKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIEC----TKLGNWSA-M 257 + C P NG ++Y + P + + C + L G + + C G W Sbjct: 1 ISCGSPPPILNGRISYYSTP-IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPA 59 Query: 258 PSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 P C+ K +V G +++ ++ HGD V+F CK Sbjct: 60 PKCEYFNKYSSCPEPIVPGGYKIRGSTPYR----HGDSVTFACK 99 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 22/63 (34%), Gaps = 2/63 (3%) Query: 21 RTCPKPDDLPFSTV-VPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC 79 C P D+ + + Y+ G +T C+ GY+ G + C W C Sbjct: 890 VNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVC 948 Query: 80 TPR 82 R Sbjct: 949 RSR 951 >5FOB-C nrPDB Length = 245 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 113/253 (44%), Gaps = 20/253 (7%) Query: 18 IAGRTCPKPDDLPFSTVVP--LKTFYEPGEEITYSCKPGYV-SRGGMRKFICPLTGLWPI 74 +P ++ F V Y G+ I Y C PGY + G C TG Sbjct: 1 SCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLF 60 Query: 75 NTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKC----TEEGKW 130 N +C R CP ++NG + ++ ++I++SCN+G+YL G + C T W Sbjct: 61 N--QCIKRRCPSPRDIDNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVW 118 Query: 131 SPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAV--FECLPQHAMFGNDTITC 188 +P+ P+C + C P P+ + R G N Y D +V + C +++ GN + C Sbjct: 119 NPKAPICESVKCQLP--PSISNGR----HNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC 172 Query: 189 TTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIEC 248 + G W+ P C+ VKCP P+ NG+++ K + Y D F C GY L G C Sbjct: 173 SG-GEWSNPPTCQIVKCPHPTIL-NGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTC 230 Query: 249 TKLGNWS-AMPSC 260 + W +P C Sbjct: 231 SPGNTWQPELPKC 243 Score = 100 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 51/230 (22%), Positives = 70/230 (30%), Gaps = 22/230 (9%) Query: 79 CTPRVCPFAGILENGAVRYTT--FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPV 136 CT P +N + +TI + C G+ G Sbjct: 3 CTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 62 Query: 137 CAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITC----TTHG 192 C CP P L + G + + C + + G C T Sbjct: 63 CIKRRCPSPRDIDNGHLDIGGVDFG------SSITYSCNSGYYLIGEYKSYCKLGSTGSM 116 Query: 193 NWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKL 251 W K P C VKC P NG N T+ C+ GYSL G + C+ Sbjct: 117 VWNPKAPICESVKCQLPPSISNGRHN-GYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSG- 174 Query: 252 GNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 G WS P+C+ + + G FK + D V F CK Sbjct: 175 GEWSNPPTCQ----IVKCPHPTILNGYLSSG---FKRSYSYNDNVDFTCK 217 >3ERB-A nrPDB Length = 223 Score = 158 bits (399), Expect = 4e-39, Method: Composition-based stats. Identities = 52/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%) Query: 20 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLW------- 72 +CP+ ++ T L + PG +TYSC G R +C +G W Sbjct: 1 APSCPQNVNISGGTFT-LSHGWAPGSLLTYSCPQGLYPSPASR--LCKSSGQWQTPGATR 57 Query: 73 PINTLKCTPRVCPFAGILENGAV--RYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKW 130 ++ C P CP ENG R ++ +SF C GF L G+ +C G W Sbjct: 58 SLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMW 117 Query: 131 SPELPVC--APIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITC 188 E VC CP P I A ++ G+ YR C + G+ C Sbjct: 118 DGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYR------CSSNLVLTGSSEREC 171 Query: 189 TTHGNWTKL-PECREV 203 +G W+ P CR+ Sbjct: 172 QGNGVWSGTEPICRQP 187 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 45/196 (22%), Positives = 65/196 (33%), Gaps = 26/196 (13%) Query: 81 PRVCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPE------ 133 CP + G + + + +++SC G Y + A S C G+W Sbjct: 1 APSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA-SRLCKSSGQWQTPGATRSL 59 Query: 134 -LPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHG 192 VC P+ CP P +F FEC + G+ C +G Sbjct: 60 SKAVCKPVRCPAPV--SFENGIYTPRLGSY--PVGGNVSFECEDGFILRGSPVRQCRPNG 115 Query: 193 NWTK-LPEC--REVKCPFPSRPDNGFVNYPAKPTLY---YKDKATFGCHDGYSLDGPEEI 246 W C CP P ++ A T + + DK + C L G E Sbjct: 116 MWDGETAVCDNGAGHCPNPG------ISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSER 169 Query: 247 ECTKLGNWSAM-PSCK 261 EC G WS P C+ Sbjct: 170 ECQGNGVWSGTEPICR 185 Score = 33.3 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 28/105 (26%), Gaps = 10/105 (9%) Query: 202 EVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNW----SAM 257 CP G T+ C G P C G W + Sbjct: 1 APSCPQNVNISGGTFTL--SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATR 57 Query: 258 PSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKN 302 KA CK A V ++ I G VSF C++ Sbjct: 58 SLSKAVCKPVRCPAPVSFEN---GIYTPRLGSYPVGGNVSFECED 99 >1ZJK-A nrPDB Length = 403 Score = 143 bits (361), Expect = 8e-35, Method: Composition-based stats. Identities = 39/160 (24%), Positives = 56/160 (35%), Gaps = 17/160 (10%) Query: 10 SSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG-----MRKF 64 + + H CP P P V P++ Y + + C+ GY G Sbjct: 4 TGWKIHYTSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTA 63 Query: 65 ICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLNGAD 120 +C G W C+ C L +G V Y T Y I +SC FY + Sbjct: 64 VCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVN 123 Query: 121 SAK--CTEEGKWSP-----ELPVCAPIICPPPSIPTFATL 153 K C +G W+ LPVC P+ C + T + Sbjct: 124 DGKYVCEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGQI 162 Score = 78.3 bits (191), Expect = 5e-15, Method: Composition-based stats. Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 23/162 (14%) Query: 83 VCPFAGILENGAVRYTT--FEYPNTISFSCNTGF------YLNGADSAKCTEEGKWSPEL 134 CP+ NG V + ++ S C TG+ + +A C ++G W + Sbjct: 16 ACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 75 Query: 135 PVCAPIICPPP-SIPTFATLRVYKPSAGNNSLYRDTAVFECLPQ-HAMFGNDT-ITCTTH 191 P C+ + C PP +P+ + P + Y+ + C + M ND C Sbjct: 76 PACSIVDCGPPDDLPSGRVEYITGPGV---TTYKAVIQYSCEETFYTMKVNDGKYVCEAD 132 Query: 192 GNWT------KLPECREVKCPFPSRPDNG--FVNYPAKPTLY 225 G WT LP C E C +R G + AKP + Sbjct: 133 GFWTSSKGEKSLPVC-EPVCGLSARTTGGQIYGGQKAKPGDF 173 >2OK5-A nrPDB Length = 752 Score = 141 bits (355), Expect = 4e-34, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 3/121 (2%) Query: 20 GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKC 79 CP+P D P +Y +EI++ C GY RG + C + G W T C Sbjct: 85 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANR-TCQVNGRWSGQTAIC 143 Query: 80 TPRV--CPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVC 137 C GI + + +++++ C+ G L G+ C E G WS P C Sbjct: 144 DNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 203 Query: 138 A 138 Sbjct: 204 Q 204 Score = 137 bits (344), Expect = 8e-33, Method: Composition-based stats. Identities = 47/208 (22%), Positives = 69/208 (33%), Gaps = 30/208 (14%) Query: 72 WPINTLKCTPRVCPFAGILENGAVRYTTFEY---PNTISFSCNTGFYLNGADSAKCTEEG 128 W + + C LE ++ +F + + C +GFY + C G Sbjct: 13 WSLARPQ---GSC----SLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTG 65 Query: 129 KWSP---------ELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHA 179 WS C I CP P F + S N D F C + Sbjct: 66 SWSTLKTQDQKTVRKAECRAIHCPRPH--DFENGEYWPRSPYYN--VSDEISFHCYDGYT 121 Query: 180 MFGNDTITCTTHGNWTK-LPEC--REVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHD 236 + G+ TC +G W+ C C P P +D T+ C Sbjct: 122 LRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP---IGTRKVGSQYRLEDSVTYHCSR 178 Query: 237 GYSLDGPEEIECTKLGNWSAM-PSCKAS 263 G +L G + C + G+WS PSC+ S Sbjct: 179 GLTLRGSQRRTCQEGGSWSGTEPSCQDS 206 Score = 121 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 40/172 (23%), Positives = 64/172 (37%), Gaps = 21/172 (12%) Query: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWP---------INTLKCTPRVCPFAGILENGA 94 G+ + Y C G+ ++ C TG W + +C CP ENG Sbjct: 40 GQALEYVCPSGFYPYP-VQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGE 98 Query: 95 VRYTT--FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVC--APIICPPPSIPTF 150 + + + ISF C G+ L G+ + C G+WS + +C C P IP Sbjct: 99 YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIG 158 Query: 151 ATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKL-PECR 201 G+ D+ + C + G+ TC G+W+ P C+ Sbjct: 159 TRKV------GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 204 Score = 107 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 13/132 (9%) Query: 172 FECLPQHAMFGNDTITCTTHGNWTKL----------PECREVKCPFPSRPDNGFVNYPAK 221 + C + T TC + G+W+ L ECR + CP P +NG +P Sbjct: 45 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY-WPRS 103 Query: 222 PTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQG-ERV 280 P D+ +F C+DGY+L G C G WS + + + G +V Sbjct: 104 PYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDN-GAGYCSNPGIPIGTRKV 162 Query: 281 KIQEKFKNGMLH 292 Q + ++ + + Sbjct: 163 GSQYRLEDSVTY 174 >4J1Y-A nrPDB Length = 397 Score = 138 bits (347), Expect = 4e-33, Method: Composition-based stats. Identities = 43/146 (29%), Positives = 57/146 (39%), Gaps = 16/146 (10%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV---SRGGMRKF--ICPLTGLWPINTL 77 CPK +D P S P K Y + + +C G+ R G F C G W + L Sbjct: 3 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 61 Query: 78 KCTPRVCPFAGILENGAVR-YTTFEYPNTISFSCNTGFYLN---GADSAKCTEEGKW--- 130 KC P C +ENG V + + + I ++C +Y G C G W Sbjct: 62 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNE 121 Query: 131 --SPELPVCAPIICPPPSIPTFATLR 154 PELP C P+ C P P R Sbjct: 122 VLGPELPKCVPV-CGVPREPFEEKAR 146 Score = 55.2 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 52/145 (35%), Gaps = 23/145 (15%) Query: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHGNWT 195 CP P V++P+ ++RD CL + TC ++G W+ Sbjct: 3 CPKEDTPN----SVWEPAKA-KYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 57 Query: 196 KLP-ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD---GPEEIECTKL 251 +C+ V C P +NG V P + + + C + Y G E C Sbjct: 58 NSKLKCQPVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYHCAGN 115 Query: 252 GNW------SAMPSCKASCKVPVKK 270 G+W +P C C VP + Sbjct: 116 GSWVNEVLGPELPKCVPVCGVPREP 140 Score = 35.6 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 33/102 (32%), Gaps = 13/102 (12%) Query: 206 PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD----GPEEI--ECTKLGNWSAMPS 259 P P V PAK ++D C DG+ + G C G WS Sbjct: 2 PCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNS-- 59 Query: 260 CKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 K C+ + +V+ E L G + + C+ Sbjct: 60 -KLKCQPVDCGIPESIENGKVEDPEST----LFGSVIRYTCE 96 >1GPZ-A nrPDB Length = 399 Score = 135 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 57/156 (36%), Gaps = 25/156 (16%) Query: 23 CPKPDDL-PFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKF-----ICPLTGLWPINT 76 CP+P L F+ + L+ Y+ + +CK GY G + +C G W Sbjct: 3 CPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAM 62 Query: 77 LKCTPRVCPFAGILENGAVRYTTFE----YPNTISFSCNTGFYLNGAD---------SAK 123 +C + C L NG RYTT Y I + C+ +Y Sbjct: 63 PRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYT 122 Query: 124 CTEEGKWSPE-----LPVCAPIICPPPSIPTFATLR 154 CT +G W E +P C P+ C P P + Sbjct: 123 CTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQRQQ 157 Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 51/154 (33%), Gaps = 27/154 (17%) Query: 82 RVCPFAGILENGAVRYT---TFEYPNTISFSCNTGFYLNGADS------AKCTEEGKWSP 132 CP L+ + +++ + +C G+ L + A C ++G W Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 133 ELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFEC-LPQHAMFGND------- 184 +P C C P R Y + G N+ Y+ + C P + M Sbjct: 61 AMPRCKIKDCGQPRNLPNGDFR-YTTTMGVNT-YKARIQYYCHEPYYKMQTRAGSRESEQ 118 Query: 185 -TITCTTHGNWTK------LPECREVKCPFPSRP 211 TCT G W +P C V C P P Sbjct: 119 GVYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNP 151 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 7/66 (10%) Query: 203 VKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL-DGPEEIE-----CTKLGNWS- 255 +KCP P D + +P ++D C GY L +G + + C G W Sbjct: 1 IKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 60 Query: 256 AMPSCK 261 AMP CK Sbjct: 61 AMPRCK 66 >4FXG-G nrPDB Length = 154 Score = 127 bits (319), Expect = 7e-30, Method: Composition-based stats. Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 17/154 (11%) Query: 15 HVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG-----MRKFICPLT 69 H CP P P V P++ Y + + C+ GY G +C Sbjct: 2 HYTSTAHACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKD 61 Query: 70 GLWPINTLKCTPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLNGADSAK-- 123 G W C+ C L +G V Y T Y I +SC FY + K Sbjct: 62 GSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYV 121 Query: 124 CTEEGKWSP-----ELPVCAPIICPPPSIPTFAT 152 C +G W+ LPVC P+ C + T Sbjct: 122 CEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGR 154 Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 36/149 (24%), Positives = 56/149 (37%), Gaps = 21/149 (14%) Query: 83 VCPFAGILENGAVRYTT--FEYPNTISFSCNTGF------YLNGADSAKCTEEGKWSPEL 134 CP+ NG V + ++ S C TG+ + +A C ++G W + Sbjct: 9 ACPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPM 68 Query: 135 PVCAPIICPPP-SIPTFATLRVYKPSAGNNSLYRDTAVFECLPQ-HAMFGNDT-ITCTTH 191 P C+ + C PP +P+ + P + Y+ + C + M ND C Sbjct: 69 PACSIVDCGPPDDLPSGRVEYITGPGV---TTYKAVIQYSCEETFYTMKVNDGKYVCEAD 125 Query: 192 GNWT------KLPECREVKCPFPSRPDNG 214 G WT LP C E C +R G Sbjct: 126 GFWTSSKGEKSLPVC-EPVCGLSARTTGG 153 Score = 47.5 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 47/148 (31%), Gaps = 9/148 (6%) Query: 142 CPPPSIPTFATLRVYKPSAGNNSLYR--DTAVFECLPQHAMFGNDTITCTTHGNWTKL-P 198 CP P P + + + +E L H + T C G+W + P Sbjct: 10 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 69 Query: 199 ECREVKCPFPSRPDNGFVNYPAKPTL-YYKDKATFGCHDGYSLD--GPEEIECTKLGNWS 255 C V C P +G V Y P + YK + C + + + C G W+ Sbjct: 70 ACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWT 129 Query: 256 AMPSCKASCKVPVKKATVVYQGERVKIQ 283 S K +PV + + Sbjct: 130 ---SSKGEKSLPVCEPVCGLSARTTGGR 154 >2QY0-A nrPDB Length = 159 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 40/160 (25%), Positives = 59/160 (36%), Gaps = 25/160 (15%) Query: 19 AGRTCPKPDDL-PFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKF-----ICPLTGLW 72 + + CP+P L F+ + L+ Y+ + +CK GY G + +C G W Sbjct: 1 STQACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTW 60 Query: 73 PINTLKCTPRVCPFAGILENGAVRYTTFE----YPNTISFSCNTGFYLNGAD-------- 120 +C + C L NG RYTT Y I + C+ +Y Sbjct: 61 HRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQ 120 Query: 121 -SAKCTEEGKWSPE-----LPVCAPIICPPPSIPTFATLR 154 CT +G W E +P C P+ C P P R Sbjct: 121 GVYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNPVEQRQR 159 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 51/153 (33%), Gaps = 27/153 (17%) Query: 83 VCPFAGILENGAVRYT---TFEYPNTISFSCNTGFYLNGADS------AKCTEEGKWSPE 133 CP L+ + +++ + +C G+ L + A C ++G W Sbjct: 4 ACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 63 Query: 134 LPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFEC-LPQHAMFGND-------- 184 +P C C P R Y + G N+ Y+ + C P + M Sbjct: 64 MPRCKIKDCGQPRNLPNGDFR-YTTTMGVNT-YKARIQYYCHEPYYKMQTRAGSRESEQG 121 Query: 185 TITCTTHGNWTK------LPECREVKCPFPSRP 211 TCT G W +P C V C P P Sbjct: 122 VYTCTAQGIWKNEQKGEKIPRCLPV-CGKPVNP 153 Score = 34.4 bits (77), Expect = 0.066, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 7/65 (10%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL-DGPEEIE-----CTKLGNWS-A 256 CP P D + +P ++D C GY L +G + + C G W A Sbjct: 4 ACPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRA 63 Query: 257 MPSCK 261 MP CK Sbjct: 64 MPRCK 68 >4LOT-A nrPDB Length = 249 Score = 125 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 15/143 (10%) Query: 11 SFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV---SRGGMRKF--I 65 + CPK +D P S P K Y + + +C G+ R G F Sbjct: 108 GWKLRYHGDPMPCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYST 166 Query: 66 CPLTGLWPINTLKCTPRVCPFAGILENGAVR-YTTFEYPNTISFSCNTGFYLN---GADS 121 C G W + LKC P C +ENG V + + + I ++C +Y G Sbjct: 167 CQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGE 226 Query: 122 AKCTEEGKW-----SPELPVCAP 139 C G W PELP C P Sbjct: 227 YHCAGNGSWVNEVLGPELPKCVP 249 Score = 58.7 bits (140), Expect = 4e-09, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 44/138 (31%), Gaps = 23/138 (16%) Query: 80 TPRVCPFAGILENGAVRYTT--FEYPNTISFSCNTGFYLNGADSA------KCTEEGKWS 131 P CP N + + + + +C GF + C GKWS Sbjct: 116 DPMPCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 174 Query: 132 PELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF---GNDTITC 188 C P+ C P + +V P ++L+ + C + G C Sbjct: 175 NSKLKCQPVDCGIPE--SIENGKVEDP---ESTLFGSVIRYTCEEPYYYMENGGGGEYHC 229 Query: 189 TTHGNWTK------LPEC 200 +G+W LP+C Sbjct: 230 AGNGSWVNEVLGPELPKC 247 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 47/126 (37%), Gaps = 17/126 (13%) Query: 139 PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHG 192 P+ CP P V++P+ ++RD CL + TC ++G Sbjct: 117 PMPCPKEDTPN----SVWEPAKA-KYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 171 Query: 193 NWTKLP-ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD---GPEEIEC 248 W+ +C+ V C P +NG V P + + + C + Y G E C Sbjct: 172 KWSNSKLKCQPVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYHC 229 Query: 249 TKLGNW 254 G+W Sbjct: 230 AGNGSW 235 Score = 33.7 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 33/102 (32%), Gaps = 13/102 (12%) Query: 206 PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD----GPEEI--ECTKLGNWSAMPS 259 P P V PAK ++D C DG+ + G C G WS Sbjct: 119 PCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNS-- 176 Query: 260 CKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 K C+ + +V+ E L G + + C+ Sbjct: 177 -KLKCQPVDCGIPESIENGKVEDPEST----LFGSVIRYTCE 213 >5UBM-B nrPDB Length = 152 Score = 124 bits (311), Expect = 5e-29, Method: Composition-based stats. Identities = 42/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV---SRGGMRKF--ICPLTGLWPINTL 77 CPK +D P S P K Y + + +C G+ R G F C G W + L Sbjct: 10 CPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKL 68 Query: 78 KCTPRVCPFAGILENGAVR-YTTFEYPNTISFSCNTGFYLN---GADSAKCTEEGKW--- 130 KC P C +ENG V + + + I ++C +Y G C G W Sbjct: 69 KCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNE 128 Query: 131 --SPELPVCAPIICPPPSIPTFATL 153 PELP C P+ C P P Sbjct: 129 VLGPELPKCVPV-CGVPREPFEEKQ 152 Score = 56.0 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 30/149 (20%), Positives = 47/149 (31%), Gaps = 24/149 (16%) Query: 80 TPRVCPFAGILENGAVRYTT--FEYPNTISFSCNTGFYLNGADSA------KCTEEGKWS 131 P CP N + + + + +C GF + C GKWS Sbjct: 6 DPMPCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 64 Query: 132 PELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF---GNDTITC 188 C P+ C P + +V P ++L+ + C + G C Sbjct: 65 NSKLKCQPVDCGIPE--SIENGKVEDP---ESTLFGSVIRYTCEEPYYYMENGGGGEYHC 119 Query: 189 TTHGNWTK------LPECREVKCPFPSRP 211 +G+W LP+C C P P Sbjct: 120 AGNGSWVNEVLGPELPKC-VPVCGVPREP 147 Score = 49.1 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 34/148 (22%), Positives = 54/148 (36%), Gaps = 23/148 (15%) Query: 139 PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHG 192 P+ CP P V++P+ ++RD CL + TC ++G Sbjct: 7 PMPCPKEDTPN----SVWEPAKA-KYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 61 Query: 193 NWTKLP-ECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD---GPEEIEC 248 W+ +C+ V C P +NG V P + + + C + Y G E C Sbjct: 62 KWSNSKLKCQPVDCGIPESIENGKVEDPE--STLFGSVIRYTCEEPYYYMENGGGGEYHC 119 Query: 249 TKLGNW------SAMPSCKASCKVPVKK 270 G+W +P C C VP + Sbjct: 120 AGNGSWVNEVLGPELPKCVPVCGVPREP 147 Score = 31.3 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 33/102 (32%), Gaps = 13/102 (12%) Query: 206 PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD----GPEEI--ECTKLGNWSAMPS 259 P P V PAK ++D C DG+ + G C G WS Sbjct: 9 PCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNS-- 66 Query: 260 CKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 K C+ + +V+ E L G + + C+ Sbjct: 67 -KLKCQPVDCGIPESIENGKVEDPEST----LFGSVIRYTCE 103 >4KKD-A nrPDB Length = 433 Score = 124 bits (311), Expect = 6e-29, Method: Composition-based stats. Identities = 37/167 (22%), Positives = 64/167 (38%), Gaps = 24/167 (14%) Query: 78 KCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD------SAKCTEEGKWS 131 +C P G +E +Y + + + SC+TG+ + + +C ++G WS Sbjct: 5 ECPELQPPVHGKIEPSQAKYF---FKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWS 61 Query: 132 PELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECL-PQHAMFGNDT--ITC 188 ++P C + C P + + N + Y+ + C P + M N+T TC Sbjct: 62 NKIPTCKIVDCRAPGELEHGLITFS--TRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTC 119 Query: 189 TTHGNWTK----------LPECREVKCPFPSRPDNGFVNYPAKPTLY 225 + G W LPEC + PS A+P L+ Sbjct: 120 SAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLF 166 Score = 94.9 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 35/146 (23%), Positives = 53/146 (36%), Gaps = 18/146 (12%) Query: 18 IAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKF-----ICPLTGLW 72 +AG CP+ + P + Y +++ SC GY + C G W Sbjct: 1 MAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTW 60 Query: 73 PINTLKCTPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLN---GADSAKCT 125 C C G LE+G + ++T Y + I +SC +Y C+ Sbjct: 61 SNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCS 120 Query: 126 EEGKWSPE-----LPVCAPIICPPPS 146 +G W + LP C P C PS Sbjct: 121 AQGVWMNKVLGRSLPTCLP-ECGQPS 145 Score = 41.4 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 13/105 (12%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL------DGPEEIECTKLGNWSAM 257 +CP P +G + P++ ++KD+ C GY + +IEC K G WS Sbjct: 5 ECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 63 Query: 258 -PSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 P+CK + +A + + + N + ++ + C+ Sbjct: 64 IPTCK----IVDCRAPGELEHGLITFSTR-NNLTTYKSEIKYSCQ 103 >4C16-A nrPDB Length = 280 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 58/243 (23%), Positives = 80/243 (32%), Gaps = 34/243 (13%) Query: 25 KPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGM-RKFICPLTGLWPINTLKCTPRV 83 KP P + +E GM C L T CT Sbjct: 67 KPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTS 126 Query: 84 CPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII-C 142 C G YT C+ GF C I+ C Sbjct: 127 CSGHGECVETINNYTC---------KCDPGFSGLK------------------CEQIVNC 159 Query: 143 PPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKL-PECR 201 P +L P GN S Y + C + +T+ C + G W+ P C Sbjct: 160 TALESPEHGSLVCSHP-LGNFS-YNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 217 Query: 202 EVKCPFPSRPDNGFVNYPAKPTLY-YKDKATFGCHDGYSLDGPEEIECTKLGNW-SAMPS 259 V+C + P NGFV P + + TF C +G+ L G + ++CT GNW + P+ Sbjct: 218 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 277 Query: 260 CKA 262 CKA Sbjct: 278 CKA 280 Score = 117 bits (293), Expect = 6e-27, Method: Composition-based stats. Identities = 37/136 (27%), Positives = 47/136 (34%), Gaps = 8/136 (5%) Query: 9 FSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPL 68 FS C + P+ PL F + SC GY+ M C Sbjct: 148 FSGLKCEQIVNCTALESPEHGSLVCSHPLGNF-SYNSSCSISCDRGYLP-SSMETMQCMS 205 Query: 69 TGLWPINTLKCTPRVC-----PFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAK 123 +G W C C P G +E +F + T +F C GF L GA S + Sbjct: 206 SGEWSAPIPACNVVECDAVTNPANGFVE-CFQNPGSFPWNTTCTFDCEEGFELMGAQSLQ 264 Query: 124 CTEEGKWSPELPVCAP 139 CT G W E P C Sbjct: 265 CTSSGNWDNEKPTCKA 280 >4IGD-A nrPDB Length = 406 Score = 107 bits (266), Expect = 8e-24, Method: Composition-based stats. Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 25/165 (15%) Query: 78 KCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD------SAKCTEEGKWS 131 +C P G +E +Y + + + SC+TG+ + + +C ++G WS Sbjct: 7 ECPELQPPVHGKIEPSQAKYF---FKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWS 63 Query: 132 PELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECL-PQHAMFGNDT--ITC 188 ++P C + C P + + N + Y+ + C P + M N+T TC Sbjct: 64 NKIPTCKIVDCRAPGELEHGLITFS--TRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTC 121 Query: 189 TTHGNWTK------LPECREVKCPFP----SRPDNGFVNYPAKPT 223 + G W LP C V C P F PA+ Sbjct: 122 SAQGVWMNKVLGRSLPTCLPV-CGLPKFSRKLMAQIFNGRPAQKG 165 Score = 96.8 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 33/146 (22%), Positives = 53/146 (36%), Gaps = 18/146 (12%) Query: 17 AIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKF-----ICPLTGL 71 ++ G CP+ + P + Y +++ SC GY + C G Sbjct: 2 SMTGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGT 61 Query: 72 WPINTLKCTPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLN---GADSAKC 124 W C C G LE+G + ++T Y + I +SC +Y C Sbjct: 62 WSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTC 121 Query: 125 TEEGKWSPE-----LPVCAPIICPPP 145 + +G W + LP C P+ C P Sbjct: 122 SAQGVWMNKVLGRSLPTCLPV-CGLP 146 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 13/105 (12%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL------DGPEEIECTKLGNWSAM 257 +CP P +G + P++ ++KD+ C GY + +IEC K G WS Sbjct: 7 ECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 65 Query: 258 -PSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK 301 P+CK + +A + + + N + ++ + C+ Sbjct: 66 IPTCK----IVDCRAPGELEHGLITFSTR-NNLTTYKSEIKYSCQ 105 >6H03-D nrPDB Length = 821 Score = 98.8 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 42/115 (36%), Gaps = 6/115 (5%) Query: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW-TKLPEC 200 CP P A + G V+ C +++ GN C W C Sbjct: 549 CPSPP----ALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHC 604 Query: 201 REVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS 255 +++ C P D G ++P KP +K T C G SL+GP C WS Sbjct: 605 QKIACVLPVLMD-GIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWS 658 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 47/130 (36%), Gaps = 8/130 (6%) Query: 84 CPFAGILENGAVRYTTFEY--PNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141 CP L++G V+ + + ++CN G+ L G A+C E+ +W C I Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIA 608 Query: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECR 201 C P + KP + C ++ G C + W+ PE + Sbjct: 609 CVLPVLMDGIQSHPQKP----FYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWS--PEMK 662 Query: 202 EVKCPFPSRP 211 +C P Sbjct: 663 NARCVQKENP 672 Score = 59.5 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 56/166 (33%), Gaps = 5/166 (3%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82 CP P L V T + G+ + Y+C GY G C W + + C Sbjct: 549 CPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNP-VARCGEDLRWLVGEMHCQKI 607 Query: 83 VCPFAGILENGAVRYTT--FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140 C +++ + ++ SC+ G L G + C KWSPE+ + Sbjct: 608 ACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCV 667 Query: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTI 186 P T A + + NS +EC P + D Sbjct: 668 QKENP--LTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDER 711 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 28/75 (37%), Gaps = 3/75 (4%) Query: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINT--LKC 79 C P + P K FY GE++T SC G +S G F+C + W +C Sbjct: 608 ACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGG-MSLEGPSAFLCGSSLKWSPEMKNARC 666 Query: 80 TPRVCPFAGILENGA 94 + P + Sbjct: 667 VQKENPLTQAVPKCQ 681 >1ELV-A nrPDB Length = 333 Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 83 VCPFAGILENGAVR-YTTFEYPNTISFSCNTGFYLN---GADSAKCTEEGKW-----SPE 133 C +ENG V + + + I ++C +Y G C G W PE Sbjct: 3 DCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPE 62 Query: 134 LPVCAPIICPPPSIPTFATLR 154 LP C P+ C P P R Sbjct: 63 LPKCVPV-CGVPREPFEEKQR 82 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 26/85 (30%), Gaps = 11/85 (12%) Query: 23 CPKPDDLPFSTVV-PLKTFYEPGEEITYSCKPGYVSR--GGMRKFICPLTGLWPINT--- 76 C P+ + V P T G I Y+C+ Y GG ++ C G W Sbjct: 4 CGIPESIENGKVEDPEST--LFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGP 61 Query: 77 --LKCTPRVCPFAGILENGAVRYTT 99 KC P C R Sbjct: 62 ELPKCVPV-CGVPREPFEEKQRIIG 85 Score = 31.3 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 29/81 (35%), Gaps = 15/81 (18%) Query: 140 IICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECL-PQHAMF--GNDTITCTTHGNWTK 196 + C P + +V P ++L+ + C P + M G C +G+W Sbjct: 2 LDCGIPE--SIENGKVEDP---ESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVN 56 Query: 197 ------LPECREVKCPFPSRP 211 LP+C C P P Sbjct: 57 EVLGPELPKC-VPVCGVPREP 76 >1MD7-A nrPDB Length = 328 Score = 73.3 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 30/90 (33%), Gaps = 19/90 (21%) Query: 83 VCPFAGILENGAVRYTTFE----YPNTISFSCNTGFYLNGAD---------SAKCTEEGK 129 C L NG RYTT Y I + C+ +Y CT +G Sbjct: 1 DCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGI 60 Query: 130 WSPE-----LPVCAPIICPPPSIPTFATLR 154 W E +P C P+ C P P R Sbjct: 61 WKNEQKGEKIPRCLPV-CGKPVNPVEQRQR 89 Score = 34.0 bits (76), Expect = 0.085, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 36/122 (29%), Gaps = 23/122 (18%) Query: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFEC-LPQHAMFGND--------TITCTTH 191 C P R Y + G N+ Y+ + C P + M TCT Sbjct: 1 DCGQPRNLPNGDFR-YTTTMGVNT-YKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQ 58 Query: 192 GNWTK------LPECREVKCPFPSRP----DNGFVNYPAKPTLY-YKDKATFGCHDGYSL 240 G W +P C V C P P AK + ++ G +L Sbjct: 59 GIWKNEQKGEKIPRCLPV-CGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGAL 117 Query: 241 DG 242 G Sbjct: 118 LG 119 >4A5W-B nrPDB Length = 913 Score = 70.6 bits (171), Expect = 8e-13, Method: Composition-based stats. Identities = 32/167 (19%), Positives = 52/167 (31%), Gaps = 14/167 (8%) Query: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82 CP+P + K Y GE++ SC G+ G + F C G W ++C Sbjct: 623 CPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFE-TVGYQYFRCLPDGTWRQGDVECQRT 681 Query: 83 VCPFAGILENGAVRYTT--FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELP---VC 137 C + E + + +I +C GF + G C W+P + C Sbjct: 682 ECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQGN-SWTPPISNSLTC 740 Query: 138 A-------PIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQ 177 C + + P + D VF+ Sbjct: 741 EKDTLTKLKGHCQLGQKQSGSECICMSPEEDCSHHSEDLCVFDTDSN 787 Score = 58.7 bits (140), Expect = 4e-09, Method: Composition-based stats. Identities = 48/294 (16%), Positives = 80/294 (27%), Gaps = 48/294 (16%) Query: 44 GEEITYSCKPGYVS----RGGMRKFICPLTGLWP--INTLKCTP-------RVCPFAGIL 90 G E C+ G + + G W + C R C Sbjct: 515 GTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNNPAPQ 574 Query: 91 ENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPE--LPVCAP-IICPPPSI 147 G +FS + + C + + E LP CP P Sbjct: 575 RGGKRCEGEKRQEEDCTFS------IMENNGQPCINDDEEMKEVDLPEIEADSGCPQPVP 628 Query: 148 PTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW-TKLPECREVKCP 206 P + + L + CL G C G W EC+ +C Sbjct: 629 PENG----FIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECI 684 Query: 207 FPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNW----SAMPSCKA 262 P + + P + + C G+ + GP C +W S +C+ Sbjct: 685 KPVVQEVLTIT-PFQRLYRIGESIELTCPKGFVVAGPSRYTCQGN-SWTPPISNSLTCEK 742 Query: 263 SCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCI 316 +K + G++ E C + E+ CS+ + C+ Sbjct: 743 DTLTKLKGHCQL--GQKQSGSECI-------------CMSPEEDCSHHSEDLCV 781 Score = 37.9 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 21 RTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWP--INTLK 78 C KP T+ P + Y GE I +C G+V G ++ C P N+L Sbjct: 681 TECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFV-VAGPSRYTCQGNSWTPPISNSLT 739 Query: 79 CTP 81 C Sbjct: 740 CEK 742 >4LOS-A nrPDB Length = 187 Score = 69.5 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 6/78 (7%) Query: 11 SFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGY---VSRGGMRKF--I 65 + CPK +D P S P K Y + + +C G+ R G F Sbjct: 111 GWKLRYHGDPMPCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYST 169 Query: 66 CPLTGLWPINTLKCTPRV 83 C G W + LKC P Sbjct: 170 CQSNGKWSNSKLKCQPVD 187 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 21/70 (30%), Gaps = 9/70 (12%) Query: 80 TPRVCPFAGILENGAVRYTT--FEYPNTISFSCNTGFYLNGADSA------KCTEEGKWS 131 P CP N + + + + +C GF + C GKWS Sbjct: 119 DPMPCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 177 Query: 132 PELPVCAPII 141 C P+ Sbjct: 178 NSKLKCQPVD 187 Score = 31.0 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 19/56 (33%), Gaps = 6/56 (10%) Query: 206 PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD----GPEEI--ECTKLGNWS 255 P P V PAK ++D C DG+ + G C G WS Sbjct: 122 PCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWS 177 >1Q3X-A nrPDB Length = 328 Score = 67.9 bits (164), Expect = 6e-12, Method: Composition-based stats. Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 12/85 (14%) Query: 80 TPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLNGADSAK--CTEEGKWSP- 132 T C L +G V Y T Y I +SC FY + K C +G W+ Sbjct: 4 TIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSS 63 Query: 133 ----ELPVCAPIICPPPSIPTFATL 153 LPVC P+ C + T + Sbjct: 64 KGEKSLPVCEPV-CGLSARTTGGRI 87 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 30/91 (32%), Gaps = 9/91 (9%) Query: 17 AIAGRTCPKPDDLPFSTVVPLKTF--YEPGEEITYSCKPGYV-SRGGMRKFICPLTGLWP 73 ++ C PDDLP V + I YSC+ + + K++C G W Sbjct: 2 SMTIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWT 61 Query: 74 INT-----LKCTPRVCPFAGILENGAVRYTT 99 + C P C + G + Sbjct: 62 SSKGEKSLPVCEPV-CGLSARTTGGRIYGGQ 91 >3TVJ-A nrPDB Length = 86 Score = 58.3 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 31/84 (36%), Gaps = 12/84 (14%) Query: 80 TPRVCPFAGILENGAVRYTT----FEYPNTISFSCNTGFYLNGADSAK--CTEEGKWSP- 132 T C L +G V Y T Y I +SC FY + K C +G W+ Sbjct: 4 TIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCDADGFWTSS 63 Query: 133 ----ELPVCAPIICPPPSIPTFAT 152 LPVC P+ C + T Sbjct: 64 KGEKSLPVCEPV-CGLSARTTGGR 86 Score = 31.0 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 29/86 (33%), Gaps = 9/86 (10%) Query: 17 AIAGRTCPKPDDLPFSTVVPLKTF--YEPGEEITYSCKPGYV-SRGGMRKFICPLTGLWP 73 ++ C PDDLP V + I YSC+ + + K++C G W Sbjct: 2 SMTIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCDADGFWT 61 Query: 74 INT-----LKCTPRVCPFAGILENGA 94 + C P C + G Sbjct: 62 SSKGEKSLPVCEPV-CGLSARTTGGR 86 >4AQB-A nrPDB Length = 361 Score = 54.1 bits (128), Expect = 9e-08, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 9/67 (13%) Query: 78 KCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD------SAKCTEEGKWS 131 +C P G +E +Y + + + SC+TG+ + + +C ++G WS Sbjct: 281 ECPELQPPVHGKIEPSQAKYF---FKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWS 337 Query: 132 PELPVCA 138 ++P C Sbjct: 338 NKIPTCK 344 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 27/90 (30%), Gaps = 13/90 (14%) Query: 5 VLILF--------SSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYV 56 VLILF + AG CP+ + P + Y +++ SC GY Sbjct: 256 VLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYK 315 Query: 57 SRGGMRKF-----ICPLTGLWPINTLKCTP 81 + C G W C Sbjct: 316 VLKDNVEMDTFQIECLKDGTWSNKIPTCKK 345 Score = 36.7 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 28/82 (34%), Gaps = 11/82 (13%) Query: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT------ITCTTHGNWT 195 CP P + + ++D + C + + ++ I C G W+ Sbjct: 282 CPELQPPVHGKIEPSQA----KYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWS 337 Query: 196 K-LPECREVKCPFPSRPDNGFV 216 +P C++ + S + V Sbjct: 338 NKIPTCKKNEIDLESELKSEQV 359 Score = 36.7 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 50/267 (18%), Positives = 84/267 (31%), Gaps = 45/267 (16%) Query: 9 FSSFLCHV-AIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICP 67 F+ F H A+ C + +D S Y G + C+ GY+ R C Sbjct: 109 FTGFDAHYMAVDVDECKEREDEELSCDHYC-HNYIGGYYCS--CRFGYILHTDNR--TCR 163 Query: 68 ---LTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCN--TGFYLN-GADS 121 L+ T T P + + ++ GF +N + Sbjct: 164 VECSDNLFTQRTGVITSPDFPNP------------YPKSSECLYTIELEEGFMVNLQFED 211 Query: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181 E+ PE+P CP + ++V G + + Sbjct: 212 IFDIED---HPEVP------CP----YDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLI 258 Query: 182 GNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL- 240 + + W +CP P +G + P++ ++KD+ C GY + Sbjct: 259 LFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIE-PSQAKYFFKDQVLVSCDTGYKVL 317 Query: 241 -----DGPEEIECTKLGNWSAM-PSCK 261 +IEC K G WS P+CK Sbjct: 318 KDNVEMDTFQIECLKDGTWSNKIPTCK 344 >1L6J-A nrPDB Length = 425 Score = 37.5 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 47/168 (27%), Gaps = 11/168 (6%) Query: 100 FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPS 159 + N +C+ F G + CT +G+ S LP C+ + + PS Sbjct: 201 TRFGNADGAACHFPFIFEGRSYSACTTDGR-SDGLPWCSTT-----ANYDTDDRFGFCPS 254 Query: 160 AGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYP 219 + + C G CTT G C D F P Sbjct: 255 ERLYTRDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWC---ATTANYDRDKLFGFCP 311 Query: 220 AKPTLYY--KDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCK 265 + + A C ++ G E CT G C + Sbjct: 312 TRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSN 359 >4F4O-C nrPDB Length = 347 Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 22/81 (27%), Gaps = 18/81 (22%) Query: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLD--GPEEIECTKLGNWSAM---- 257 CP P P P Y + + C Y L G W+ Sbjct: 32 SCPKP----------PEIPKGYVEHMVRYHCQTYYKLRTAGDGVYTLDSNKQWTNKVTGE 81 Query: 258 --PSCKASCKVPVKKATVVYQ 276 P C+A C P V + Sbjct: 82 KLPECEAVCGKPKNPVDQVQR 102 >1CK7-A nrPDB Length = 631 Score = 32.9 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 42/162 (25%), Gaps = 10/162 (6%) Query: 100 FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPS 159 +Y N C F NG + CT+ G+ + C + P Sbjct: 194 VKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDG------FLWCSTTYNFEKDGKYGFCPH 247 Query: 160 AGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYP 219 ++ + C G +CTT G C + D + P Sbjct: 248 EALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTE---DYDRDKKYGFCP 304 Query: 220 AKPTLYYKDKAT-FGCHDGYSLDGPEEIECTKLGNWSAMPSC 260 + C ++ G + CT G C Sbjct: 305 ETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWC 346 >1EAK-A nrPDB Length = 421 Score = 31.7 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 42/162 (25%), Gaps = 10/162 (6%) Query: 100 FEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPS 159 +Y N C F NG + CT+ G+ + C + P Sbjct: 192 VKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDG------FLWCSTTYNFEKDGKYGFCPH 245 Query: 160 AGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYP 219 ++ + C G +CTT G C + D + P Sbjct: 246 EALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTE---DYDRDKKYGFCP 302 Query: 220 AKPTLYYKDKAT-FGCHDGYSLDGPEEIECTKLGNWSAMPSC 260 + C ++ G + CT G C Sbjct: 303 ETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWC 344 >3U2P-A nrPDB Length = 497 Score = 31.7 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 49/159 (30%), Gaps = 23/159 (14%) Query: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVN 217 P N +L C H +CT C+ + + +G Sbjct: 145 PWPSNLTLVSTNGSSGCGRCHK-------SCTGRCWGPTENHCQTLTRTVCAEQCDGRCY 197 Query: 218 YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQG 277 P Y D C G S GP++ +C N++ +C V T VY Sbjct: 198 GP-----YVSDCCHRECAGGCS--GPKDTDCFACMNFNDSGAC-----VTQCPQTFVYNP 245 Query: 278 ERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCI 316 +++ F +G FC K + + C+ Sbjct: 246 TTFQLEHNFNAKYTYGA----FCVKKCPHNFVVDSSSCV 280 >6FO0-R nrPDB Length = 274 Score = 31.3 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 19/43 (44%) Query: 3 SPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGE 45 SPVL L S LC ++ G+ +P S VP Y + Sbjct: 40 SPVLDLKRSVLCRESLRGQAAGRPLVASVSLNVPASVRYSHTD 82 >3EHU-A nrPDB Length = 476 Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 18/54 (33%), Gaps = 3/54 (5%) Query: 153 LRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNW---TKLPECREV 203 + S + R F ++ N C +G+W EC+E+ Sbjct: 403 GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEI 456 >5GUP-Ae nrPDB Length = 78 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 3 SPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFY 41 SPVL SFLC +++G+ +P VP Y Sbjct: 40 SPVLDAKRSFLCRESLSGQAAGRPLVASVGLNVPASVRY 78 >3U9U-E nrPDB Length = 625 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 42/136 (30%), Gaps = 19/136 (13%) Query: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVN 217 P N +L C H +CT C+ + + +G Sbjct: 145 PWPSNLTLVSTNGSSGCGRCHK-------SCTGRCWGPTENHCQTLTRTVCAEQCDGRCY 197 Query: 218 YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQG 277 P Y D C G S GP++ +C N++ +C V T VY Sbjct: 198 GP-----YVSDCCHRECAGGCS--GPKDTDCFACMNFNDSGAC-----VTQCPQTFVYNP 245 Query: 278 ERVKIQEKFKNGMLHG 293 +++ F +G Sbjct: 246 TTFQLEHNFNAKYTYG 261 Score = 27.9 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 20/69 (28%), Gaps = 2/69 (2%) Query: 124 CTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGN 183 C+ +G W P C C S D+ EC PQ + Sbjct: 482 CSSDGCWGPGPDQCLS--CRRFSRGRICIESCNLYDGEFREFENDSICVECDPQCEKMED 539 Query: 184 DTITCTTHG 192 +TC G Sbjct: 540 GLLTCHGPG 548 >5XWD-A nrPDB Length = 651 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 42/137 (30%), Gaps = 14/137 (10%) Query: 124 CTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGN 183 C+ EG W PE C + C S + ++ +C P+ Sbjct: 510 CSPEGCWGPEPRDC--VSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAM 567 Query: 184 DTITCTTHG--------NWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCH 235 + ITCT G ++ P C + CP +N + + + C Sbjct: 568 N-ITCTGRGPDNCIQCAHYIDGPHCVK-TCPAGVMGENNTLVWKYADAGHVCHLCHPNCT 625 Query: 236 DGYSLDGPEEIECTKLG 252 G GP C G Sbjct: 626 YG--CTGPGLEGCPTNG 640 >3FL7-A nrPDB Length = 536 Score = 29.0 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 25/156 (16%), Positives = 45/156 (28%), Gaps = 16/156 (10%) Query: 57 SRGGMRKFICPLTGLWPINTLK--CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGF 114 G + C + G W + + C + + + FE + C Sbjct: 243 PGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHT 302 Query: 115 YLN--GADSAKCTEEGKWSPELPVCAPIICPPPSIPTF-------ATLRVYKPSAGNNSL 165 + GA S +C E +P+ P P C P + + +S Sbjct: 303 LPSPEGATSCECEEGFFRAPQDPASMP--CTRPPSAPHYLTAVGMGAKVELRWTPPQDSG 360 Query: 166 YRDTAVFE--CLPQHAMFGNDTITCTTHGNWTKLPE 199 R+ V+ C G C +++ P Sbjct: 361 GREDIVYSVTCEQCWPESGECG-PCEASVRYSEPPH 395 >5ZJI-N nrPDB Length = 145 Score = 28.3 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 20/74 (27%), Gaps = 6/74 (8%) Query: 181 FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL 240 + T+ N+ + C FP K + D C Sbjct: 76 LNDKKRMATSAANFARAYTVEFGSCQFPYNFTGCQDLAKQKKVPFLSDDLEIEC------ 129 Query: 241 DGPEEIECTKLGNW 254 +G E+ +C W Sbjct: 130 EGKEKFKCGSNVFW 143 >3MX0-A nrPDB Length = 409 Score = 28.3 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 25/156 (16%), Positives = 45/156 (28%), Gaps = 16/156 (10%) Query: 57 SRGGMRKFICPLTGLWPINTLK--CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGF 114 G + C + G W + + C + + + FE + C Sbjct: 212 PGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHT 271 Query: 115 YLN--GADSAKCTEEGKWSPELPVCAPIICPPPSIPTF-------ATLRVYKPSAGNNSL 165 + GA S +C E +P+ P P C P + + +S Sbjct: 272 LPSPEGATSCECEEGFFRAPQDPASMP--CTRPPSAPHYLTAVGMGAKVELRWTPPQDSG 329 Query: 166 YRDTAVFE--CLPQHAMFGNDTITCTTHGNWTKLPE 199 R+ V+ C G C +++ P Sbjct: 330 GREDIVYSVTCEQCWPESGECG-PCEASVRYSEPPH 364 >2GTH-A nrPDB Length = 370 Score = 27.5 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 24/57 (42%), Gaps = 1/57 (1%) Query: 261 KASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCID 317 + K ++ + + I + + + K S FC + K C YT D QCI+ Sbjct: 57 ELFAKRSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYT-DLQCIE 112 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.120 0.370 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,062,326 Number of Sequences: 36641 Number of extensions: 560922 Number of successful extensions: 1574 Number of sequences better than 10.0: 45 Number of HSP's better than 10.0 without gapping: 40 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 1100 Number of HSP's gapped (non-prelim): 178 length of query: 345 length of database: 10,336,785 effective HSP length: 98 effective length of query: 247 effective length of database: 6,745,967 effective search space: 1666253849 effective search space used: 1666253849 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.5 bits)