BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P02699 (348 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5DYS-A nrPDB 708 0.0 5W0P-A nrPDB 657 0.0 6CMO-R nrPDB 604 e-173 4WW3-A nrPDB 139 2e-33 3AYN-A nrPDB 139 2e-33 5ZBQ-A nrPDB 109 2e-24 5ZBH-A nrPDB 86 2e-17 4MQS-A nrPDB 86 3e-17 6DDF-R nrPDB 86 3e-17 5C1M-A nrPDB 86 3e-17 2KS9-A nrPDB 81 5e-16 5DHG-A nrPDB 76 3e-14 6ME9-A nrPDB 74 6e-14 6MET-B nrPDB 73 1e-13 6B73-A nrPDB 71 7e-13 6C1Q-B nrPDB 70 2e-12 3PWH-A nrPDB 69 3e-12 4DKL-A nrPDB 69 3e-12 6IBL-A nrPDB 68 5e-12 5O9H-A nrPDB 68 8e-12 6GDG-A nrPDB 66 2e-11 6A94-A nrPDB 66 3e-11 2VT4-A nrPDB 66 3e-11 5UIW-A nrPDB 65 3e-11 6AKX-A nrPDB 65 3e-11 4LDO-A nrPDB 65 6e-11 4RWA-A nrPDB 64 1e-10 4GBR-A nrPDB 63 2e-10 6J20-A nrPDB 62 3e-10 6G79-S nrPDB 62 3e-10 5CXV-A nrPDB 62 3e-10 5UNF-A nrPDB 61 6e-10 4IAR-A nrPDB 61 9e-10 5V54-A nrPDB 60 2e-09 5ZKB-A nrPDB 60 2e-09 6CM4-A nrPDB 59 3e-09 6BQH-A nrPDB 59 4e-09 4ZUD-A nrPDB 57 9e-09 4BWB-A nrPDB 57 1e-08 4DJH-A nrPDB 57 1e-08 3UON-A nrPDB 57 1e-08 5DSG-A nrPDB 57 2e-08 4XNV-A nrPDB 56 2e-08 3PBL-A nrPDB 56 3e-08 6N4B-R nrPDB 55 3e-08 4BUO-A nrPDB 55 4e-08 3SN6-R nrPDB 55 4e-08 2R4S-A nrPDB 55 7e-08 5WS3-A nrPDB 53 2e-07 4XEE-A nrPDB 52 4e-07 4EJ4-A nrPDB 52 4e-07 6GPS-A nrPDB 52 4e-07 4U15-A nrPDB 52 5e-07 4U14-A nrPDB 51 6e-07 6HLP-A nrPDB 51 7e-07 5VBL-B nrPDB 50 1e-06 6DRY-A nrPDB 50 1e-06 5LWE-A nrPDB 50 2e-06 3P0G-A nrPDB 49 4e-06 6GPX-A nrPDB 49 4e-06 6DO1-A nrPDB 48 6e-06 4XT3-A nrPDB 48 8e-06 5WB1-A nrPDB 48 8e-06 5WIV-A nrPDB 47 1e-05 3RZE-A nrPDB 47 2e-05 4Z36-A nrPDB 46 2e-05 5XSZ-A nrPDB 46 2e-05 5U09-A nrPDB 46 2e-05 5T1A-A nrPDB 46 3e-05 4ZJC-A nrPDB 45 3e-05 2LNL-A nrPDB 45 4e-05 5GLI-A nrPDB 45 5e-05 5GLH-A nrPDB 45 5e-05 5XRA-A nrPDB 44 9e-05 5UVI-A nrPDB 44 1e-04 4GRV-A nrPDB 44 1e-04 5WF6-A nrPDB 43 2e-04 3V2Y-A nrPDB 43 2e-04 5XJM-A nrPDB 40 0.001 4NTJ-A nrPDB 40 0.001 5NJ6-A nrPDB 39 0.003 5NDD-A nrPDB 39 0.005 5N2S-A nrPDB 39 0.005 3VW7-A nrPDB 38 0.005 3OE9-A nrPDB 35 0.035 6D9H-R nrPDB 33 0.12 5UEN-A nrPDB 33 0.18 4PHU-A nrPDB 33 0.21 5ZTY-A nrPDB 32 0.49 1V9D-A nrPDB 31 0.62 3OBV-E nrPDB 31 0.67 4WMJ-A nrPDB 29 3.1 5ZKQ-A nrPDB 29 3.6 2YEV-A nrPDB 28 6.3 5ZKP-A nrPDB 28 7.7 >5DYS-A nrPDB Length = 349 Score = 708 bits (1827), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/348 (99%), Positives = 345/348 (99%) Query: 1 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 60 M GTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY Sbjct: 2 MCGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 61 Query: 61 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG 120 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT LYTSLHGYFVFGPTGCNLEGFFATLG Sbjct: 62 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTILYTSLHGYFVFGPTGCNLEGFFATLG 121 Query: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 180 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP Sbjct: 122 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 181 Query: 181 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 240 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES Sbjct: 182 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 241 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS FGPIFMTIPAFFAKTSAV Sbjct: 242 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSCFGPIFMTIPAFFAKTSAV 301 Query: 301 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA 348 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA Sbjct: 302 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA 349 >5W0P-A nrPDB Length = 906 Score = 657 bits (1694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/347 (92%), Positives = 333/347 (95%) Query: 1 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 60 M GTEGPNFYVPFSN TGVVRSPFE PQYYLAEPWQFSMLAAYMFLLI+LGFPINFLTLY Sbjct: 161 MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLY 220 Query: 61 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG 120 VTVQHKKLRTPLNYILLNLAVADLFMV GGFT+TLYTSLHGYFVFGPTGCNL+GFFATLG Sbjct: 221 VTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG 280 Query: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 180 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPL GWSRYIP Sbjct: 281 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIP 340 Query: 181 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 240 EG+QCSCGIDYYT E NNESFVIYMFVVHF IP+I+IFFCYGQLVFTVKEAAAQQQES Sbjct: 341 EGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES 400 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 ATTQKAEKEVTRMVII VIAFLICW+PYA VAFYIFTHQGS FGPIFMTIPAFFAK++A+ Sbjct: 401 ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQGSCFGPIFMTIPAFFAKSAAI 460 Query: 301 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAP 347 YNPVIYIMMNKQFRNCM+TT+CCGKNPLGDDEAS TVSKTETSQVAP Sbjct: 461 YNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAP 507 >6CMO-R nrPDB Length = 463 Score = 604 bits (1558), Expect = e-173, Method: Compositional matrix adjust. Identities = 298/323 (92%), Positives = 310/323 (95%) Query: 1 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 60 M GTEGPNFYVPFSN TGVVRSPFE PQYYLAEPWQFSMLAAYMFLLI+LGFPINFLTLY Sbjct: 141 MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLY 200 Query: 61 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG 120 VTVQHKKLRTPLNYILLNLAVADLFMV GGFT+TLYTSLHGYFVFGPTGCNL+GFFATLG Sbjct: 201 VTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG 260 Query: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 180 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPL GWSRYIP Sbjct: 261 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIP 320 Query: 181 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 240 EG+QCSCGIDYYT E NNESFVIYMFVVHF IP+I+IFFCYGQLVFTVKEAAAQQQES Sbjct: 321 EGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES 380 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 ATTQKAEKEVTRMVII VIAFLICW+PYA VAFYIFTHQGS FGPIFMTIPAFFAK++A+ Sbjct: 381 ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQGSCFGPIFMTIPAFFAKSAAI 440 Query: 301 YNPVIYIMMNKQFRNCMVTTLCC 323 YNPVIYIMMNKQFRNCM+TT+CC Sbjct: 441 YNPVIYIMMNKQFRNCMLTTICC 463 >4WW3-A nrPDB Length = 350 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 85/289 (29%), Positives = 151/289 (52%), Gaps = 33/289 (11%) Query: 60 YVTVQHKKLRTPLNYILLNLAVADL-FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFAT 118 Y+ + K L+TP N ++NLA +D F + GF + ++FG C + GF Sbjct: 49 YLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGG 108 Query: 119 LGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSR 177 + G +++ ++ +++I+RY V+ +PM+ + + A + + F W+ ++ A P+ GW Sbjct: 109 IFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGA 168 Query: 178 YIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTV----KEA 233 Y EG+ C+C DY + ++ S ++ MF++ F P+++IFFCY +V +V KE Sbjct: 169 YTLEGVLCNCSFDYIS--RDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEM 226 Query: 234 AA--------QQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGP 285 AA + +++ AE + ++ I++V FL+ W PYA VA + FGP Sbjct: 227 AAMAKRLNAKELRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALL------AQFGP 280 Query: 286 I------FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL-----CC 323 + +P FAK SA++NP+IY + + +FR + T CC Sbjct: 281 LEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCC 329 >3AYN-A nrPDB Length = 448 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 85/289 (29%), Positives = 151/289 (52%), Gaps = 33/289 (11%) Query: 60 YVTVQHKKLRTPLNYILLNLAVADL-FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFAT 118 Y+ + K L+TP N ++NLA +D F + GF + ++FG C + GF Sbjct: 57 YLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGG 116 Query: 119 LGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSR 177 + G +++ ++ +++I+RY V+ +PM+ + + A + + F W+ ++ A P+ GW Sbjct: 117 IFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGA 176 Query: 178 YIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTV----KEA 233 Y EG+ C+C DY + ++ S ++ MF++ F P+++IFFCY +V +V KE Sbjct: 177 YTLEGVLCNCSFDYIS--RDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEM 234 Query: 234 AA--------QQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGP 285 AA + +++ AE + ++ I++V FL+ W PYA VA + FGP Sbjct: 235 AAMAKRLNAKELRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALL------AQFGP 288 Query: 286 I------FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL-----CC 323 + +P FAK SA++NP+IY + + +FR + T CC Sbjct: 289 LEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCC 337 >5ZBQ-A nrPDB Length = 525 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 88/356 (24%), Positives = 161/356 (45%), Gaps = 22/356 (6%) Query: 5 EGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ 64 E + + FS K + + FE +L F++ AY +I+LG N + + ++ Sbjct: 9 ENHSVHSNFSEKNAQLLA-FENDDCHLPLAMIFTLALAYG-AVIILGVSGNLALIIIILK 66 Query: 65 HKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIA 124 K++R N +++NL+ +DL + T +L ++VFG C L F + ++ Sbjct: 67 QKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVS 126 Query: 125 LWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQ 184 +WSLV++A+ER+ ++ P +R HA +G+A WV+A+A + P L+ + E Q Sbjct: 127 IWSLVLIAVERHQLIINP-RGWRPNNRHAYVGIAVIWVLAVASSLPFLI-YQVMTDEPFQ 184 Query: 185 CSCGIDYYTPH--------EETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQ 236 + +D Y +++ S+ + V+ + PL IF CY ++ +K Sbjct: 185 -NVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNM 243 Query: 237 QQESATTQKAEKEVTR---MVIIMVIAFLICWLPYAGV-AFYIFTHQ---GSDFGPIFMT 289 + + E R M++ +V+AF +CWLP + + HQ + +F+ Sbjct: 244 MDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFL- 302 Query: 290 IPAFFAKTSAVYNPVIYIMMNKQF-RNCMVTTLCCGKNPLGDDEASTTVSKTETSQ 344 + A S NP+ Y +NK F R+ C DD + +S T + Sbjct: 303 LCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDE 358 >5ZBH-A nrPDB Length = 527 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 61/236 (25%), Positives = 115/236 (48%), Gaps = 13/236 (5%) Query: 5 EGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ 64 E + + FS K + + FE +L F++ AY +I+LG N + + ++ Sbjct: 19 ENHSVHSNFSEKNAQLLA-FENDDCHLPLAMIFTLALAYG-AVIILGVSGNLALIIIILK 76 Query: 65 HKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIA 124 K++R N +++NL+ +DL + T +L ++VFG C L F + ++ Sbjct: 77 QKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVS 136 Query: 125 LWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQ 184 +WSLV++A+ER+ ++ P +R HA +G+A WV+A+A + P L+ + E Q Sbjct: 137 IWSLVLIAVERHQLIINPRG-WRPNNRHAYVGIAVIWVLAVASSLPFLI-YQVMTDEPFQ 194 Query: 185 CSCGIDYYTPH--------EETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKE 232 + +D Y +++ S+ + V+ + PL IF CY ++ +K Sbjct: 195 -NVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR 249 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 27/125 (21%), Positives = 51/125 (40%), Gaps = 6/125 (4%) Query: 225 QLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGV-AFYIFTHQ---G 280 +++ T + ++ K + M++ +V+AF +CWLP + + HQ Sbjct: 397 RVITTFRTGTWDAYDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIAT 456 Query: 281 SDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQF-RNCMVTTLCCGKNPLGDDEASTTVSK 339 + +F+ + A S NP+ Y +NK F R+ C DD + +S Sbjct: 457 CNHNLLFL-LCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMST 515 Query: 340 TETSQ 344 T + Sbjct: 516 MHTDE 520 >4MQS-A nrPDB Length = 351 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 79/311 (25%), Positives = 141/311 (45%), Gaps = 35/311 (11%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT- 97 ++A + L+ ++G N L + ++ L+T NY L +LA ADL + G F+ LYT Sbjct: 45 LVAGSLSLVTIIG---NILVMVSIKVNRHLQTVNNYFLFSLACADL--IIGVFSMNLYTL 99 Query: 98 -SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIM 155 ++ GY+ GP C+L + ++ +L++++ +RY V KP++ + A M Sbjct: 100 YTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGM 159 Query: 156 GVAFTWVMALACAAPPLVGWS-----RYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVV 210 +A WV++ AP ++ W R + +G C I +++ N + + Sbjct: 160 MIAAAWVLSFILWAPAILFWQFIVGVRTVEDG---ECYIQFFS------NAAVTFGTAIA 210 Query: 211 HFIIPLIVIFFCY--------GQLVFTVKEAAAQQQESATTQK----AEKEVTRMVIIMV 258 F +P+I++ Y ++ KE A Q +T +K EK+VTR ++ ++ Sbjct: 211 AFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSTRKKPPPSREKKVTRTILAIL 270 Query: 259 IAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMV 318 +AF+I W PY V I T TI + ++ NP Y + N F+ Sbjct: 271 LAFIITWAPY-NVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFK 329 Query: 319 TTLCCGKNPLG 329 L C +G Sbjct: 330 HLLMCHYKNIG 340 >6DDF-R nrPDB Length = 356 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/272 (26%), Positives = 132/272 (48%), Gaps = 21/272 (7%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL----YTSLHGYFVFGPTGC 110 NFL +YV V++ K++T N + NLA+AD T+TL L G + FG C Sbjct: 84 NFLVMYVIVRYTKMKTATNIYIFNLALADALA-----TSTLPFQSVNYLMGTWPFGNILC 138 Query: 111 NLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGVAFTWVMALACA 168 + ++++L ++++RY+ VC P+ +FR N I+ V W+++ A Sbjct: 139 KIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVC-NWILSSAIG 197 Query: 169 APPL-VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLV 227 P + + ++Y + C+ + T + E I +F+ FI+P+++I CYG ++ Sbjct: 198 LPVMFMATTKYRQGSIDCTLTFSHPTWYWE---NLLKICVFIFAFIMPVLIITVCYGLMI 254 Query: 228 FTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLP---YAGVAFYIFTHQGSDFG 284 +K + S + + +TRMV+++V F++CW P Y + I T + F Sbjct: 255 LRLK-SVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALI-TIPETTFQ 312 Query: 285 PIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 + T++ NPV+Y +++ F+ C Sbjct: 313 TVSWHFCIALGYTNSCLNPVLYAFLDENFKRC 344 >5C1M-A nrPDB Length = 296 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/272 (26%), Positives = 132/272 (48%), Gaps = 21/272 (7%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL----YTSLHGYFVFGPTGC 110 NFL +YV V++ K++T N + NLA+AD T+TL L G + FG C Sbjct: 35 NFLVMYVIVRYTKMKTATNIYIFNLALADALA-----TSTLPFQSVNYLMGTWPFGNILC 89 Query: 111 NLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGVAFTWVMALACA 168 + ++++L ++++RY+ VC P+ +FR N I+ V W+++ A Sbjct: 90 KIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVC-NWILSSAIG 148 Query: 169 APPL-VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLV 227 P + + ++Y + C+ + T + E I +F+ FI+P+++I CYG ++ Sbjct: 149 LPVMFMATTKYRQGSIDCTLTFSHPTWYWE---NLLKICVFIFAFIMPVLIITVCYGLMI 205 Query: 228 FTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLP---YAGVAFYIFTHQGSDFG 284 +K + S + + +TRMV+++V F++CW P Y + I T + F Sbjct: 206 LRLK-SVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALI-TIPETTFQ 263 Query: 285 PIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 + T++ NPV+Y +++ F+ C Sbjct: 264 TVSWHFCIALGYTNSCLNPVLYAFLDENFKRC 295 >2KS9-A nrPDB Length = 364 Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 77/317 (24%), Positives = 146/317 (46%), Gaps = 17/317 (5%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 P ++ WQ + AA ++++ N + +++ + HK++RT NY L+NLA A+ M Sbjct: 22 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASM 81 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 ++H + +G C FF +++S+ +A +RY+ + P+ Sbjct: 82 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQP- 140 Query: 147 RFGENHAIMGVAFTWVMALACAAPP-LVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI 205 R + + WV+AL A P + +P + C I++ + + + I Sbjct: 141 RLSATATKVVICVIWVLALLLAFPQGYYSTTETMPS--RVVCMIEWPEHPNKIYEKVYHI 198 Query: 206 YMFVVHFIIPLIVIFFCYGQLVFTV--KEAAAQQQESATTQ-KAEKEVTRMVIIMVIAFL 262 + V+ + +PL+VI + Y + T+ E + Q A+++V +M+I++V F Sbjct: 199 CVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFA 258 Query: 263 ICWLPYAGVAFYIFTHQGSDF------GPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 ICWLP+ F++ + D +++ I + A +S +YNP+IY +N +FR Sbjct: 259 ICWLPFH--IFFLLPYINPDLYLKKFIQQVYLAI-MWLAMSSTMYNPIIYCCLNDRFRLG 315 Query: 317 MVTTL-CCGKNPLGDDE 332 CC GD E Sbjct: 316 FKHAFRCCPFISAGDYE 332 >5DHG-A nrPDB Length = 424 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 74/291 (25%), Positives = 130/291 (44%), Gaps = 36/291 (12%) Query: 51 GFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD----LFMVFGGFTTTLYTSLHGYFVFG 106 G N L +YV ++H K++T N + NLA+AD L + F G L G++ FG Sbjct: 139 GLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILL-----GFWPFG 193 Query: 107 PTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGVAFTWVMA 164 C + ++L ++++RYV +C P+ + R + VA W +A Sbjct: 194 NALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAI-WALA 252 Query: 165 LACAAP-PLVGWSRYIPEGMQCSCGI----DYYTPHEETNNESFVIYMFVVHFIIPLIVI 219 P ++G ++ E ++C I DY+ P F I +F+ FI+P++VI Sbjct: 253 SVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGP-------VFAICIFLFSFIVPVLVI 305 Query: 220 FFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQ 279 CY ++ ++ S + + +TR+V+++V F+ CW P V ++ Q Sbjct: 306 SVCYSLMIRRLR-GVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTP---VQVFVLA-Q 360 Query: 280 GSDFGPIFMTIPAFFAKTSAV------YNPVIYIMMNKQFRNCMVTTLCCG 324 G P T A +A+ NP++Y +++ F+ C CC Sbjct: 361 GLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACF-RKFCCA 410 >6ME9-A nrPDB Length = 460 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 51/216 (23%), Positives = 99/216 (45%), Gaps = 14/216 (6%) Query: 28 QYYLAE----PWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD 83 Q YL + W L+A + + + N L + ++++KLR N L++LA+A+ Sbjct: 103 QKYLGDGARPSWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALAN 162 Query: 84 LFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM 143 L + F + L + + FG C F L ++W++ +AI+RY+ +C M Sbjct: 163 LVVAFYPYPLILVAIFYDGWAFGEEHCKASAFVMGLSVIGSVWNITAIAIDRYLYICHSM 222 Query: 144 SNFR-FGENHAIMGVAFTWVMALACAAPP-LVGWSRYIPEGMQCSCGIDYYTPHEETNNE 201 + R + H + + W++ + P VG Y P C+ +T + Sbjct: 223 AYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCT--------FIQTAST 274 Query: 202 SFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQ 237 + + V+HF++P+ V+ FCY ++ V +A ++ Sbjct: 275 QYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARMKK 310 >6MET-B nrPDB Length = 313 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 75/317 (23%), Positives = 140/317 (44%), Gaps = 36/317 (11%) Query: 20 VRSPFEAPQYYLAEPWQ---FSMLAAYMF-----LLIMLGFPINFLTLYVTVQHKKLRTP 71 V SP YY +EP Q +AA + L+ + GF N L + + + K+L++ Sbjct: 5 VSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSM 64 Query: 72 LNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVL 131 + LLNLA++DLF + Y + + FG T C L +G ++ +++L Sbjct: 65 TDIYLLNLAISDLFFLLTVPFWAHYAA--AQWDFGNTMCQLLTGLYFIGFFSGIFFIILL 122 Query: 132 AIERYVVVCKPMSNFRFGENHAIMGV---AFTWVMALACAAPPLVGWSRYIPEGMQCSCG 188 I+RY+ V + F GV TWV+A+ + P ++ ++R EG+ +C Sbjct: 123 TIDRYLAVVHAV--FALKARTVTFGVVTSVITWVVAVFASLPGII-FTRSQKEGLHYTCS 179 Query: 189 IDY-YTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAE 247 + Y+ ++ N + + ++ ++PL+V+ CY ++ T+ +K Sbjct: 180 SHFPYSQYQFWKNFQ-TLKIVILGLVLPLLVMVICYSGILKTLLRCR--------NEKKR 230 Query: 248 KEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQ---------GSDFGPIFMTIPAFFAKTS 298 R++ ++I + + W PY + + T Q S+ M + T Sbjct: 231 HRAVRLIFTIMIVYFLFWAPY-NIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTH 289 Query: 299 AVYNPVIYIMMNKQFRN 315 NP+IY + ++FRN Sbjct: 290 CCINPIIYAFVGEKFRN 306 >6B73-A nrPDB Length = 418 Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 62/291 (21%), Positives = 136/291 (46%), Gaps = 24/291 (8%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD-LFMVFGGFTTTLYT 97 ++ A ++ ++G N L ++V +++ K++T N + NLA+AD L F +T+Y Sbjct: 121 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVY- 179 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIM 155 L + FG C + ++++L +++++RY+ VC P+ +FR I+ Sbjct: 180 -LMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKII 238 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEGMQC-SCGIDYYTPHEETNNESFVIYMFVVHFII 214 + W+++ + +V + E + C + + + I +F+ F+I Sbjct: 239 NICI-WLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVI 297 Query: 215 PLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY 274 P+++I CY ++ +K + S + + +TR+V+++V F++CW P + Sbjct: 298 PVLIIIVCYTLMILRLK-SVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTP-----IH 351 Query: 275 IF---------THQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 IF +H + + I + +S NP++Y +++ F+ C Sbjct: 352 IFILVEALGSTSHSTAALSSYYFCIALGYTNSS--LNPILYAFLDENFKRC 400 >6C1Q-B nrPDB Length = 422 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 78/293 (26%), Positives = 132/293 (45%), Gaps = 35/293 (11%) Query: 42 AYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL-- 99 A +FL+ +LG N L ++VT K RT LNLAVAD L+TS+ Sbjct: 131 AVVFLVGVLG---NALVVWVTAFEAK-RTINAIWFLNLAVADFLSCLA--LPILFTSIVQ 184 Query: 100 HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM--SNFRFGENHAIMGV 157 H ++ FG C++ L ++ L ++ +R+++V KP+ NFR G A + Sbjct: 185 HHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFR-GAGLAWIAC 243 Query: 158 AFTWVMALACAAPPL---VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFII 214 A W +AL P V Y P + CG+DY H++ + I V+ F+ Sbjct: 244 AVAWGLALLLTIPSFLYRVVREEYFPP--KVLCGVDY--SHDKRRERAVAIVRLVLGFLW 299 Query: 215 PLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY 274 PL+ + CY F + +++ +T + ++V+ +V +F I WLPY Sbjct: 300 PLLTLTICY---TFILLRTWSRRATRST------KTLKVVVAVVASFFIFWLPYQVTGIM 350 Query: 275 IFTHQGSDFGPIFMTIPAF------FAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 + + S P F+ + FA + NP+IY++ + F+ + +L Sbjct: 351 MSFLEPS--SPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSL 401 >3PWH-A nrPDB Length = 329 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 64/277 (23%), Positives = 118/277 (42%), Gaps = 19/277 (6%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEG 114 N L + + L+ NY +++LA AD+ + G ++ F GC Sbjct: 24 NVLVCWAVWLNSNLQNVTNYFVVSLAAADILV--GVLAIPFAITISTGFCAACHGCLFIA 81 Query: 115 FFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLV 173 F + + +++SL+ +AI+RY+ + P+ N A +A WV++ A P++ Sbjct: 82 CFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPML 141 Query: 174 GWSR--YIPEGMQCSCGI---DYYTPHEETNNESFVIYM-FVVHFIIPLIVIFFCYGQLV 227 GW+ EG S G E+ ++++Y F ++PL+++ Y + + Sbjct: 142 GWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLR-I 200 Query: 228 FTVKEAAAQQQESA--------TTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQ 279 F +Q ES +T + E + I+ F +CWLP + + F Sbjct: 201 FAAARRQLKQMESQPLPGERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCP 260 Query: 280 GSDFGPIF-MTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 P++ M + A T++V NP IY ++FR Sbjct: 261 DCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQ 297 >4DKL-A nrPDB Length = 464 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 51/194 (26%), Positives = 97/194 (50%), Gaps = 16/194 (8%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL----YTSLHG 101 ++ ++G NFL +YV V++ K++T N + NLA+AD T+TL L G Sbjct: 26 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALA-----TSTLPFQSVNYLMG 80 Query: 102 YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGVAF 159 + FG C + ++++L ++++RY+ VC P+ +FR N I+ V Sbjct: 81 TWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVC- 139 Query: 160 TWVMALACAAPPL-VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIV 218 W+++ A P + + ++Y + C+ + T + E I +F+ FI+P+++ Sbjct: 140 NWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWE---NLLKICVFIFAFIMPVLI 196 Query: 219 IFFCYGQLVFTVKE 232 I CYG ++ +K Sbjct: 197 ITVCYGLMILRLKS 210 >6IBL-A nrPDB Length = 416 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 72/286 (25%), Positives = 131/286 (45%), Gaps = 32/286 (11%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLF--MVFGGFTTTL 95 S+L A + LLI+ G N L + ++L+T N + +LA ADL ++ F TL Sbjct: 116 SLLMALVVLLIVAG---NVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATL 172 Query: 96 YTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG----EN 151 + G +++G C L L ++ +L V+AI+RY+ + P FR+ Sbjct: 173 V--VRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSP---FRYQSLMTRA 227 Query: 152 HAIMGVAFTW-VMALACAAPPLVGWSR-YIPEGMQCSCGIDYYTPH--EETNNESFVIYM 207 A + + W + AL P ++ W R P+ ++C Y P + N ++ I Sbjct: 228 RAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKC-----YQDPGCCDFVTNRAYAIAS 282 Query: 208 FVVHFIIPLIVIFFCYGQLVFTVKE------AAAQQQESATTQKAEKEVTRMVIIMVIAF 261 ++ F IPL+++ F Y ++ KE A++++ S E + + + I++ F Sbjct: 283 SIISFYIPLLIMIFVYLRVYREAKEQIRKIDRASKRKTSRVMAMKEHKALKTLGIIMGVF 342 Query: 262 LICWLPYAGVAFYIFTHQGSDFGPIFMTIP-AFFAKTSAVYNPVIY 306 +CWLP+ V I D P ++ + + ++ NP+IY Sbjct: 343 TLCWLPFFLV--NIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIY 386 >5O9H-A nrPDB Length = 317 Score = 67.8 bits (164), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 78/286 (27%), Positives = 129/286 (45%), Gaps = 33/286 (11%) Query: 42 AYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL-- 99 A +FL+ +LG N L ++VT K RT LNLAVAD L+TS+ Sbjct: 16 AVVFLVGVLG---NALVVWVTAFEAK-RTINAIWFLNLAVADFLACLA--LPALFTSIVQ 69 Query: 100 HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVA 158 H ++ FG C++ L ++ L ++ +R+++V KP RF G A + A Sbjct: 70 HHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPAWCQRFRGAGLAWILCA 129 Query: 159 FTWVMALACAAPP---LVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIP 215 W +AL P V Y P + CG+DY H++ + I V+ F+ P Sbjct: 130 VAWGLALLLTIPSALYRVVREEYFPP--KVLCGVDY--SHDKRRERAVAIVRLVLGFLWP 185 Query: 216 LIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI 275 L+ + CY ++ ++ +A++ S T K +V+ +V +F I WLPY + Sbjct: 186 LLTLTICYTFIL--LRTWSARETRSTKTLK-------VVVAVVASFFIFWLPYQVTGIMM 236 Query: 276 FTHQGSDFGPIFMTIPAF------FAKTSAVYNPVIYIMMNKQFRN 315 + S P F+ + FA + NP+IY++ + F+ Sbjct: 237 SFLEPSS--PTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQG 280 >6GDG-A nrPDB Length = 479 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/282 (21%), Positives = 117/282 (41%), Gaps = 29/282 (10%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEG 114 N L + + L+ NY +++LA AD+ G ++ F GC Sbjct: 187 NVLVCWAVWLNSNLQNVTNYFVVSLAAADI--AVGVLAIPFAITISTGFCAACHGCLFIA 244 Query: 115 FFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLV 173 F + + +++SL+ +AI+RY+ + P+ N A +A WV++ A P++ Sbjct: 245 CFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPML 304 Query: 174 GW------------SRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFF 221 GW S+ EG Q +C + P V + F ++PL+++ Sbjct: 305 GWNNCGQPKEGKAHSQGCGEG-QVACLFEDVVPM-----NYMVYFNFFACVLVPLLLMLG 358 Query: 222 CYGQLVFTVKEAAAQQ-------QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY 274 Y ++ + Q + + +T + E + + I+V F +CWLP + + Sbjct: 359 VYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCF 418 Query: 275 IFTHQGSDFGPIF-MTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 F P++ M + + T++V NP IY ++FR Sbjct: 419 TFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ 460 >6A94-A nrPDB Length = 376 Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 55/220 (25%), Positives = 105/220 (47%), Gaps = 21/220 (9%) Query: 30 YLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG 89 +L E ++L A + +L + G N L + KKL+ NY L++LA+AD+ + F Sbjct: 4 HLQEKNWSALLTAVVIILTIAG---NILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFL 60 Query: 90 GFTTTLYTSLHGYFVFGPTG-CNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF 148 ++ T L+GY P+ C + + L +W L ++++RYV + P+ + RF Sbjct: 61 VMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRF 120 Query: 149 G-ENHAIMGVAFTWVMALACAAP-PLVGW---SRYIPEGMQCSCGIDYYTPHEETNNESF 203 A + + W +++ + P P+ G S+ EG SC + +++F Sbjct: 121 NSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEG---SCLL---------ADDNF 168 Query: 204 VIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATT 243 V+ V F IPL ++ Y + ++++ AA +++ T Sbjct: 169 VLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWET 208 Score = 28.1 bits (61), Expect = 6.3, Method: Compositional matrix adjust. Identities = 23/108 (21%), Positives = 45/108 (41%), Gaps = 14/108 (12%) Query: 230 VKEAAAQQQESATTQKA-----------EKEVTRMVIIMVIAFLICWLPY--AGVAFYIF 276 VKEA A ++ TT A E++ +++ I+ F++ W P+ + I Sbjct: 263 VKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVIC 322 Query: 277 THQ-GSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 D + + + S+ NP++Y + NK +R+ + C Sbjct: 323 KESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQC 370 >2VT4-A nrPDB Length = 313 Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 74/294 (25%), Positives = 134/294 (45%), Gaps = 34/294 (11%) Query: 31 LAEPWQ--FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLF--M 86 L++ W+ S+L A + LLI+ G N L + ++L+T N + +LA ADL + Sbjct: 6 LSQQWEAGMSLLMALVVLLIVAG---NVLVIAAIGSTQRLQTLTNLFITSLACADLVVGL 62 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 + F TL + G +++G C L L ++ +L V+AI+RY+ + P F Sbjct: 63 LVVPFGATLV--VRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSP---F 117 Query: 147 RFG----ENHAIMGVAFTW-VMALACAAPPLVGWSR-YIPEGMQCSCGIDYYTPH--EET 198 R+ A + + W + AL P ++ W R P+ ++C Y P + Sbjct: 118 RYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKC-----YQDPGCCDFV 172 Query: 199 NNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEA-----AAQQQESATTQKAEKEVTRM 253 N ++ I ++ F IPL+++ F ++ KE A +++ + K + + Sbjct: 173 TNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRKIDRASKRKRVMLMREHKALKTL 232 Query: 254 VIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIP-AFFAKTSAVYNPVIY 306 IIM + F +CWLP+ V I D P ++ + + ++ NP+IY Sbjct: 233 GIIMGV-FTLCWLPFFLVN--IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIY 283 >5UIW-A nrPDB Length = 411 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 77/359 (21%), Positives = 142/359 (39%), Gaps = 69/359 (19%) Query: 20 VRSPFEAPQYYLAEPWQ---FSMLAAYMF-----LLIMLGFPINFLTLYVTVQHKKLRTP 71 V SP YY +EP Q +AA + L+ + GF N L + + + +K+L++ Sbjct: 7 VSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSM 66 Query: 72 LNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVL 131 + LLNLA++DLF + Y + + FG T C L +G ++ +++L Sbjct: 67 TDIYLLNLAISDLFFLLTVPFWAHYAAAQ--WDFGNTMCQLLTGLYFIGFFSGIFFIILL 124 Query: 132 AIERYVVVCKPMSNFRFGENHAIMGV---AFTWVMALACAAPPLVGWSRYIPEGMQCSCG 188 I+RY+ V + F GV TWV+A+ + P ++ ++R EG+ +C Sbjct: 125 TIDRYLAVVHAV--FALKARTVTFGVVTSVITWVVAVFASLPNII-FTRSQKEGLHYTCS 181 Query: 189 IDY-YTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKE--------------- 232 + Y+ ++ N + + ++ ++PL+V+ CY ++ T+ Sbjct: 182 SHFPYSQYQFWKNFQ-TLKIVILGLVLPLLVMVICYSGILKTLLRMKKYTCTVCGYIYNP 240 Query: 233 ----------------------------AAAQQQESATTQKAEKEVTRMVIIMVIAFLIC 264 Q E +K R++ ++I + + Sbjct: 241 EDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEEEKKRHRDVRLIFTIMIVYFLF 300 Query: 265 WLPYAGVA--------FYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 W PY V F + S+ M + T NP+IY + ++FRN Sbjct: 301 WAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRN 359 >6AKX-A nrPDB Length = 381 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 77/360 (21%), Positives = 143/360 (39%), Gaps = 71/360 (19%) Query: 20 VRSPFEAPQYYLAEPWQ---FSMLAAYMF-----LLIMLGFPINFLTLYVTVQHKKLRTP 71 V SP YY +EP Q +AA + L+ + GF N L + + + +K+L++ Sbjct: 7 VSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSM 66 Query: 72 LNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVL 131 + LLNLA++DLF + Y + + FG T C L +G ++ +++L Sbjct: 67 TDIYLLNLAISDLFFLLTVPFWAHYAAAQ--WDFGNTMCQLLTGLYFIGFFSGIFFIILL 124 Query: 132 AIERYVVVCKPMSNFRFGENHAIMGV---AFTWVMALACAAPPLVGWSRYIPEGMQCSCG 188 I+RY+ V + F GV TWV+A+ + P ++ ++R EG+ +C Sbjct: 125 TIDRYLAVVHAV--FALKARTVTFGVVTSVITWVVAVFASLPNII-FTRSQKEGLHYTCS 181 Query: 189 IDY-YTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKE--------------- 232 + Y+ ++ N + + ++ ++PL+V+ CY ++ T+ Sbjct: 182 SHFPYSQYQFWKNFQ-TLKIVILGLVLPLLVMVICYSGILKTLLRMKKYTCTVCGYIYNP 240 Query: 233 ----------------------------AAAQQQESATTQKAEKEVTRMVIIMVIAFLIC 264 Q E +K R++ ++I + + Sbjct: 241 EDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEEEKKRHRDVRLIFTIMIVYFLF 300 Query: 265 WLPYAGVAFYIFTHQ---------GSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 W PY + + T Q S+ M + T NP+IY + ++FRN Sbjct: 301 WAPY-NIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRN 359 >4LDO-A nrPDB Length = 469 Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 72/312 (23%), Positives = 135/312 (43%), Gaps = 30/312 (9%) Query: 29 YYLAEPWQFSM--LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 Y E W M + + + L I+ G N L + + ++L+T NY + +LA ADL M Sbjct: 175 YAADEVWVVGMGIVMSLIVLAIVFG---NVLVITAIAKFERLQTVTNYFITSLACADLVM 231 Query: 87 VFGGFTTTLYTSLH---GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM 143 G + + H + FG C L ++ +L V+A++RY + P Sbjct: 232 ---GLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPF 288 Query: 144 S-NFRFGENHAIMGVAFTWVMA-LACAAPPLVGWSRYI-PEGMQC----SCGIDYYTPHE 196 +N A + + W+++ L P + W R E + C +C D++T Sbjct: 289 KYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETC-CDFFT--- 344 Query: 197 ETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVII 256 N+++ I +V F +PL+++ F Y ++ +EA Q Q+ E + + + I Sbjct: 345 ---NQAYAIASSIVSFYVPLVIMVFVYSRV---FQEAKRQLQKIDKFALKEHKALKTLGI 398 Query: 257 MVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 ++ F +CWLP+ V +++ + + ++ +NP+IY + FR Sbjct: 399 IMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLN-WIGYVNSGFNPLIYC-RSPDFRIA 456 Query: 317 MVTTLCCGKNPL 328 LC ++ L Sbjct: 457 FQELLCLRRSSL 468 >4RWA-A nrPDB Length = 411 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 70/293 (23%), Positives = 137/293 (46%), Gaps = 29/293 (9%) Query: 50 LGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFV----F 105 +G N L ++ V++ K++T N + NLA+AD T+TL Y + F Sbjct: 135 VGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALA-----TSTLPFQSAKYLMETWPF 189 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGVAFTWVM 163 G C ++++L +++++RY+ VC P+ +FR ++ + WV+ Sbjct: 190 GELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICI-WVL 248 Query: 164 ALACAAPPLV-GWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFC 222 A P +V +R P C + + +P + + I +F+ F++P+++I C Sbjct: 249 ASGVGVPIMVMAVTR--PRDGAVVCMLQFPSPSWYWDTVT-KICVFLFAFVVPILIITVC 305 Query: 223 YGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSD 282 YG ++ + + S ++ + +TRMV+++V AF++CW P + ++T D Sbjct: 306 YGLMLLRL-RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI-HIFVIVWTLVDID 363 Query: 283 ------FGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG 329 + + I +A +S NPV+Y +++ F+ C LC + P G Sbjct: 364 RRDPLVVAALHLCIALGYANSS--LNPVLYAFLDENFKRCF-RQLC--RKPCG 411 >4GBR-A nrPDB Length = 309 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 71/308 (23%), Positives = 134/308 (43%), Gaps = 30/308 (9%) Query: 33 EPWQFSM--LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG 90 E W M + + + L I+ G N L + + ++L+T NY + +LA ADL M G Sbjct: 2 EVWVVGMGIVMSLIVLAIVFG---NVLVITAIAKFERLQTVTNYFITSLACADLVM---G 55 Query: 91 FTTTLYTSLH---GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NF 146 + + H + FG C L ++ +L V+A++RY + P Sbjct: 56 LAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS 115 Query: 147 RFGENHAIMGVAFTWVMA-LACAAPPLVGWSRYI-PEGMQC----SCGIDYYTPHEETNN 200 +N A + + W+++ L P + W R E + C +C D++T N Sbjct: 116 LLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETC-CDFFT------N 168 Query: 201 ESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIA 260 +++ I +V F +PL+++ F Y ++ +EA Q Q+ E + + + I++ Sbjct: 169 QAYAIASSIVSFYVPLVIMVFVYSRV---FQEAKRQLQKIDKFCLKEHKALKTLGIIMGT 225 Query: 261 FLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTT 320 F +CWLP+ V +++ + + ++ +NP+IY + FR Sbjct: 226 FTLCWLPFFIVNIVHVIQDNLIRKEVYILLN-WIGYVNSGFNPLIY-CRSPDFRIAFQEL 283 Query: 321 LCCGKNPL 328 LC ++ L Sbjct: 284 LCLRRSSL 291 >6J20-A nrPDB Length = 441 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 46/198 (23%), Positives = 91/198 (45%), Gaps = 4/198 (2%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 P ++ WQ + AA ++++ N + +++ + HK++RT NY L+NLA A+ M Sbjct: 21 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFANASM 80 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 ++H + +G C FF ++WS+ +A +RY+ + P+ Sbjct: 81 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIWSMTAVAFDRYMAIIHPLQP- 139 Query: 147 RFGENHAIMGVAFTWVMALACAAPP-LVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI 205 R + + WV+AL A P + +P + C I++ + + + I Sbjct: 140 RLSATATKVVICVIWVLALLLAFPQGYYSTTETMPS--RVVCMIEWPEHPNKIYEKVYHI 197 Query: 206 YMFVVHFIIPLIVIFFCY 223 + V+ + +PL+VI + Y Sbjct: 198 CVTVLIYFLPLLVIGYAY 215 Score = 34.3 bits (77), Expect = 0.092, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 9/60 (15%) Query: 261 FLICWLPYAGVAFYIFTHQGSDF------GPIFMTIPAFFAKTSAVYNPVIYIMMNKQFR 314 F ICWLP+ F++ + D +++ I + A +S +YNP+IY +N +FR Sbjct: 363 FAICWLPFH--IFFLLPYINPDLYLKKFIQQVYLAI-MWLAMSSTMYNPIIYCCLNDRFR 419 >6G79-S nrPDB Length = 364 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 22/234 (9%) Query: 28 QYYLAEPWQ--FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLF 85 Q ++ PW+ ML A + L L T+Y T +KL TP NY++ +LAV DL Sbjct: 9 QDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRT---RKLHTPANYLIASLAVTDLL 65 Query: 86 M-VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM- 143 + + +T+YT + G + G C+ ++W L V+A++RY + + Sbjct: 66 VSILVMPISTMYT-VTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVE 124 Query: 144 -SNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNES 202 S R + A+M +A WV +++ + PP W + E C ++ T++ Sbjct: 125 YSAKRTPKRAAVM-IALVWVFSISISLPPFF-WRQAKAEEEVSECVVN-------TDHIL 175 Query: 203 FVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVII 256 + +Y V F P +++ YG++ + +Q T + K +TR +I Sbjct: 176 YTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQ----TPNRTGKRLTRAQLI 225 Score = 35.4 bits (80), Expect = 0.035, Method: Compositional matrix adjust. Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Query: 224 GQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI-FTHQGSD 282 Q+ V +A ++++ + E++ T+ + I++ AF++CWLP+ ++ + Sbjct: 256 NQVKVRVSDALLEKKKLMAAR--ERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACW 313 Query: 283 FGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 F + +++ NP+IY M N+ F+ Sbjct: 314 FHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQ 346 >5CXV-A nrPDB Length = 515 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 5/151 (3%) Query: 34 PWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT 93 PWQ + + LL + N L L + +L+T NY LL+LA ADL + G F+ Sbjct: 47 PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADL--IIGTFSM 104 Query: 94 TLYTS--LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGE 150 LYT+ L G++ G C+L + + ++ +L++++ +RY V +P+S + Sbjct: 105 NLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTP 164 Query: 151 NHAIMGVAFTWVMALACAAPPLVGWSRYIPE 181 A + + W+++ AP ++ W + E Sbjct: 165 RRAALMIGLAWLVSFVLWAPAILFWQYLVGE 195 Score = 32.0 bits (71), Expect = 0.37, Method: Compositional matrix adjust. Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIY 306 EK+ R + +++AF++ W PY + + T + + ++ NP+ Y Sbjct: 409 EKKAARTLSAILLAFILTWTPY-NIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCY 467 Query: 307 IMMNKQFRNCMVTTLCC 323 + NK FR+ L C Sbjct: 468 ALCNKAFRDTFRLLLLC 484 >5UNF-A nrPDB Length = 411 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 57/230 (24%), Positives = 104/230 (45%), Gaps = 5/230 (2%) Query: 45 FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFV 104 +++ ++GF +N + + + K + + + NLAVADL ++ Y S ++ Sbjct: 128 YIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWL 187 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMA 164 FGP C + G F TL +++ + ++++RY V P + R A V W MA Sbjct: 188 FGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMA 247 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMF-VVHFIIPLIVIFFCY 223 + P E + + I + P + + + M ++ FIIPLI I CY Sbjct: 248 CLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCY 307 Query: 224 GQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAF 273 F +++ + + +V +M +V+AF+ICWLP+ + F Sbjct: 308 ----FGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTF 353 >4IAR-A nrPDB Length = 401 Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 55/221 (24%), Positives = 101/221 (45%), Gaps = 18/221 (8%) Query: 28 QYYLAEPWQ--FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLF 85 Q ++ PW+ ML A + L L T+Y T +KL TP NY++ +LAV DL Sbjct: 12 QDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRT---RKLHTPANYLIASLAVTDLL 68 Query: 86 M-VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM- 143 + + +T+YT + G + G C+ ++W L V+A++RY + + Sbjct: 69 VSILVMPISTMYT-VTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVE 127 Query: 144 -SNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNES 202 S R + A+M +A WV +++ + PP W + E C ++ T++ Sbjct: 128 YSAKRTPKRAAVM-IALVWVFSISISLPPFF-WRQAKAEEEVSECVVN-------TDHIL 178 Query: 203 FVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATT 243 + +Y V F P +++ YG++ + A +++ T Sbjct: 179 YTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWET 219 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 10/96 (10%) Query: 230 VKEAAAQQQESATTQKA---------EKEVTRMVIIMVIAFLICWLPYAGVAFYI-FTHQ 279 VKEA A ++ TT+ A E++ T+ + I++ AF++CWLP+ ++ + Sbjct: 294 VKEAQAAAEQLKTTRNAYIQKYLAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKD 353 Query: 280 GSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 F + +++ NP+IY M N+ F+ Sbjct: 354 ACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQ 389 >5V54-A nrPDB Length = 395 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 55/221 (24%), Positives = 100/221 (45%), Gaps = 18/221 (8%) Query: 28 QYYLAEPWQ--FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLF 85 Q ++ PW+ ML A + L L T+Y T +KL TP NY++ +LAV DL Sbjct: 5 QDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRT---RKLHTPANYLIASLAVTDLL 61 Query: 86 M-VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM- 143 + + +T+YT + G + G C+ ++W L V+A++RY + + Sbjct: 62 VSILVMPISTMYT-VTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVE 120 Query: 144 -SNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNES 202 S R + A+M +A WV +++ + PP W + E C ++ T++ Sbjct: 121 YSAKRTPKRAAVM-IALVWVFSISISLPPFF-WRQAKAEEEVSECVVN-------TDHIL 171 Query: 203 FVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATT 243 + +Y V F P +++ YG++ + A ++ T Sbjct: 172 YTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDRWRT 212 Score = 34.3 bits (77), Expect = 0.082, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYI-FTHQGSDFGPIFMTIPAFFAKTSAVYNPVI 305 E++ T+ + I++ AF++CWLP+ ++ + F + +++ NP+I Sbjct: 314 ERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPII 373 Query: 306 YIMMNKQFRN 315 Y M N+ F+ Sbjct: 374 YTMSNEDFKQ 383 >5ZKB-A nrPDB Length = 421 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 52/213 (24%), Positives = 100/213 (46%), Gaps = 22/213 (10%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT- 97 ++A + L+ ++G N L + ++ L+T NY L +LA ADL + G F+ LYT Sbjct: 30 LVAGSLSLVTIIG---NILVMVSIKVNRHLQTVNNYFLFSLACADL--IIGVFSMNLYTL 84 Query: 98 -SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIM 155 ++ GY+ GP C+L + + +L++++ +RY V KP++ + A M Sbjct: 85 YTVIGYWPLGPVVCDLWLALDYVVSNARVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGM 144 Query: 156 GVAFTWVMALACAAPPLVGWS-----RYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVV 210 +A WV++ AP ++ W R + +G C I +++ N + + Sbjct: 145 MIAAAWVLSFILWAPAILFWQFIVGVRTVEDG---ECYIQFFS------NAAVTFGTAIA 195 Query: 211 HFIIPLIVIFFCYGQLVFTVKEAAAQQQESATT 243 F +P+I++ Y + K A +++ T Sbjct: 196 AFYLPVIIMTVLYWHISRASKSRIADLEDNWET 228 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 12/111 (10%) Query: 230 VKEAAAQQQESATTQKA-----------EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH 278 VKEA A ++ TT+ A EK+VTR ++ +++AF+I W PY V I T Sbjct: 303 VKEAQAAAEQLKTTRNAYIQKYLPPPSREKKVTRTILAILLAFIITWAPY-NVMVLINTF 361 Query: 279 QGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG 329 TI + ++ NP Y + N F+ L C +G Sbjct: 362 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIG 412 >6CM4-A nrPDB Length = 430 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 15/199 (7%) Query: 41 AAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLH 100 A + LLI + N L + K L+T NY++++LAVADL + +Y + Sbjct: 4 ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVV 63 Query: 101 GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM-SNFRFGENHAI-MGVA 158 G + F C++ + + +L ++I+RY V PM N R+ + + ++ Sbjct: 64 GEWKFSRIHCDIFVTLDVMMCTASALNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIS 123 Query: 159 FTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIV 218 WV++ + P L G + Q C I N +FV+Y +V F +P IV Sbjct: 124 IVWVLSFTISCPLLFG----LNNADQNECIIA---------NPAFVVYSSIVSFYVPFIV 170 Query: 219 IFFCYGQLVFTVKEAAAQQ 237 Y ++ ++ + Sbjct: 171 TLLVYIKIYIVLRRRRKRN 189 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%) Query: 243 TQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYN 302 +Q+ EK+ T+M I+ F+ICWLP+ + + H + P+ + + ++ N Sbjct: 351 SQQKEKKATQMAAIVAGVFIICWLPFF-ITHILNIHCDCNIPPVLYSAFTWLGYVNSAVN 409 Query: 303 PVIYIMMNKQFRNCMVTTLCC 323 P+IY N +FR + L C Sbjct: 410 PIIYTTFNIEFRKAFLKILHC 430 >6BQH-A nrPDB Length = 452 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 45/194 (23%), Positives = 87/194 (44%), Gaps = 19/194 (9%) Query: 57 LTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYF-----VFGPTGCN 111 L + KKL NY L++LA+AD+ + +L L+ Y P + Sbjct: 60 LVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWIS 119 Query: 112 LEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMALACAAP 170 L+ F+T ++ L ++++RYV + P+ + RF AIM +A W +++ + P Sbjct: 120 LDVLFST----ASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVP 175 Query: 171 -PLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFT 229 P++G + + + N+ +FV+ V F IPL ++ Y ++ Sbjct: 176 IPVIGLRDEEKVFVNNTTCV--------LNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV 227 Query: 230 VKEAAAQQQESATT 243 ++ AA +++ T Sbjct: 228 LRRQAADLEDNWET 241 Score = 30.8 bits (68), Expect = 0.96, Method: Compositional matrix adjust. Identities = 24/109 (22%), Positives = 45/109 (41%), Gaps = 14/109 (12%) Query: 230 VKEAAAQQQESATTQKA-----------EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH 278 VKEA A ++ TT+ A E++ ++++ I+ FLI W P+ Sbjct: 316 VKEAQAAAEQLKTTRNAYIQKYLQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLC 375 Query: 279 QGS---DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCG 324 + S + + + ++ NP++Y + NK +R L C Sbjct: 376 EKSCNQKLMEKLLNVFVWIGYVNSGINPLVYTLFNKIYRRAFSNYLRCN 424 >4ZUD-A nrPDB Length = 410 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 60/288 (20%), Positives = 122/288 (42%), Gaps = 13/288 (4%) Query: 37 FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 F M+ ++ ++G N L + V + KL+T + LLNLA+ADL + +Y Sbjct: 123 FVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVY 182 Query: 97 TSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM-SNFRFGENHAIM 155 T++ + FG C + + +++ L L+I+RY+ + PM S R A + Sbjct: 183 TAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKV 242 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIP 215 W++A + P ++ + + E + +Y T + ++ F+ P Sbjct: 243 TCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFP 302 Query: 216 LIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY- 274 ++I Y + +K+A Q+ + ++ ++++ +V+ F W+P+ F Sbjct: 303 FLIILTSYTLIWKALKKAYEIQK----NKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLD 358 Query: 275 -------IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 I + +D M I A + NP+ Y + K+F+ Sbjct: 359 VLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 406 >4BWB-A nrPDB Length = 338 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/300 (23%), Positives = 129/300 (43%), Gaps = 23/300 (7%) Query: 44 MFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL--HG 101 +F++ +G + TL + L++ ++Y L +LA++DL ++ LY + H Sbjct: 29 LFVVGTVGNGVTLFTLARKKSLQSLQSRVDYYLGSLALSDLLILLFALPVDLYNFIWVHH 88 Query: 102 YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM-SNFRFGENHAIMGVAFT 160 + FG GC F ++V L++E Y+ +C P + + ++ Sbjct: 89 PWAFGDAGCKGYYFLREACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAI 148 Query: 161 WVMALACAAPPL-------VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFI 213 W+ + A P L + P G+ C+ +D T +F+ ++F + Sbjct: 149 WLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIVDTATLRVVIQLNTFMSFLF--PML 206 Query: 214 IPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIM---VIAFLICWLPYAG 270 + I+ +L V +AA +Q T + + R V+++ VIAF++CWLPY Sbjct: 207 VASILNTVAARRLTVMVHQAA-EQGRVCTEPGRVQALRRGVLVLRAVVIAFVVCWLPYHV 265 Query: 271 VAF---YIFTHQGS----DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 YI Q + DF F + SA NP++Y +++ FR ++TL C Sbjct: 266 RRLMFVYISDEQWTTALFDFYHYFYMLSNALVYVSAAINPILYNLVSANFRQVFLSTLAC 325 >4DJH-A nrPDB Length = 480 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 43/198 (21%), Positives = 95/198 (47%), Gaps = 7/198 (3%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD-LFMVFGGFTTTLYT 97 ++ A ++ ++G N L ++V +++ K++T N + NLA+AD L F +T+Y Sbjct: 24 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVY- 82 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIM 155 L + FG C + ++++L +++++RY+ VC P+ +FR I+ Sbjct: 83 -LMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKII 141 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEGMQC-SCGIDYYTPHEETNNESFVIYMFVVHFII 214 + W+++ + +V + E + C + + + I +F+ F+I Sbjct: 142 NICI-WLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVI 200 Query: 215 PLIVIFFCYGQLVFTVKE 232 P+++I CY ++ +K Sbjct: 201 PVLIIIVCYTLMILRLKS 218 >3UON-A nrPDB Length = 467 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 22/196 (11%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT- 97 ++A + L+ ++G N L + ++ L+T NY L +LA ADL + G F+ LYT Sbjct: 28 LVAGSLSLVTIIG---NILVMVSIKVNRHLQTVNNYFLFSLACADL--IIGVFSMNLYTL 82 Query: 98 -SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAIM 155 ++ GY+ GP C+L + ++ +L++++ +RY V KP++ + A M Sbjct: 83 YTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGM 142 Query: 156 GVAFTWVMALACAAPPLVGWS-----RYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVV 210 +A WV++ AP ++ W R + +G C I +++ N + + Sbjct: 143 MIAAAWVLSFILWAPAILFWQFIVGVRTVEDG---ECYIQFFS------NAAVTFGTAIA 193 Query: 211 HFIIPLIVIFFCYGQL 226 F +P+I++ Y + Sbjct: 194 AFYLPVIIMTVLYWHI 209 Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIY 306 EK+VTR ++ +++AF+I W PY V I T TI + ++ NP Y Sbjct: 383 EKKVTRTILAILLAFIITWAPY-NVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACY 441 Query: 307 IMMNKQFRNCMVTTLCCGKNPLG 329 + N F+ L C +G Sbjct: 442 ALCNATFKKTFKHLLMCHYKNIG 464 >5DSG-A nrPDB Length = 422 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 21/148 (14%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS--LHGYF 103 +L+ML +N ++L+T NY L +LA ADL + G F+ LYT + GY+ Sbjct: 32 ILVMLSIKVN----------RQLQTVNNYFLFSLACADL--IIGAFSMNLYTVYIIKGYW 79 Query: 104 VFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAFTWV 162 G C+L + ++ +L++++ +RY V KP++ R A + +A WV Sbjct: 80 PLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWV 139 Query: 163 MALACAAPPLVGW-----SRYIPEGMQC 185 ++ AP ++ W R +P+ QC Sbjct: 140 LSFVLWAPAILFWQFVVGKRTVPDN-QC 166 Score = 34.7 bits (78), Expect = 0.065, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIY 306 E++VTR + +++AF++ W PY V + T S +I + ++ NP Y Sbjct: 330 ERKVTRTIFAILLAFILTWTPY-NVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACY 388 Query: 307 IMMNKQFRNCMVTTLCCGKNPLG 329 + N F+ L C +G Sbjct: 389 ALCNATFKKTFRHLLLCQYRNIG 411 >4XNV-A nrPDB Length = 421 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 50/196 (25%), Positives = 87/196 (44%), Gaps = 8/196 (4%) Query: 36 QFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL 95 QF L A L+ ++GF N + +++ V H K + ++ + NLA+AD V Sbjct: 49 QFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIF 108 Query: 96 YTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGENHAI 154 Y ++FG C L+ F + ++ L ++ RY V P+ + R + +AI Sbjct: 109 YYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAI 168 Query: 155 MGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMF---VVH 211 W++ + +P L Y G++ + I Y + S+ IY V Sbjct: 169 CISVLVWLIVVVAISPILF----YSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAM 224 Query: 212 FIIPLIVIFFCYGQLV 227 F +PL++I CYG +V Sbjct: 225 FCVPLVLILGCYGLIV 240 >3PBL-A nrPDB Length = 481 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 22/195 (11%) Query: 44 MFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLH-GY 102 + L I+ G N L ++ + L+T NY++++LAVADL + +Y + G Sbjct: 48 LILAIVFG---NGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGV 104 Query: 103 FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHA-----IMGV 157 + F C++ + ++W+L ++I+RY V P+ +++ G + + + Sbjct: 105 WNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPV-HYQHGTGQSSCRRVALMI 163 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 WV+A A + P L G++ G C I +N FVIY VV F +P Sbjct: 164 TAVWVLAFAVSCPLLFGFN---TTGDPTVCSI---------SNPDFVIYSSVVSFYLPFG 211 Query: 218 VIFFCYGQLVFTVKE 232 V Y ++ +K+ Sbjct: 212 VTVLVYARIYVVLKQ 226 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 2/80 (2%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH-QGSDFGPIFMTIPAFFAKTSAVYNPVI 305 EK+ T+MV I++ AF++CWLP+ + + TH Q P + + ++ NPVI Sbjct: 396 EKKATQMVAIVLGAFIVCWLPFF-LTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVI 454 Query: 306 YIMMNKQFRNCMVTTLCCGK 325 Y N +FR + L CG+ Sbjct: 455 YTTFNIEFRKAFLKILSCGR 474 >6N4B-R nrPDB Length = 495 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 77/318 (24%), Positives = 130/318 (40%), Gaps = 61/318 (19%) Query: 55 NFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLE 113 N L L V + + LR P + + +LAVADL G +Y+ + + N+ Sbjct: 149 NLLVLCVILHSRSLRCRPSYHFIGSLAVADLL----GSVIFVYSFIDFHVFHRKDSRNV- 203 Query: 114 GFFATLGGEIA-----LWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALAC 167 F LGG A + SL + AI+RY+ + +P++ R A++ W +A+ Sbjct: 204 -FLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVI 262 Query: 168 AAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLV 227 A PL+GW+ E +Q C D + PH + E+++++ V ++ L+ I + Y ++ Sbjct: 263 AVLPLLGWN---CEKLQSVCS-DIF-PHID---ETYLMFWIGVTSVL-LLFIVYAYMYIL 313 Query: 228 F-------------TVKEAAAQQQESATTQKAEKEVTRMVIIMV-------IAFLICWLP 267 + T K E Q + RM I + + +ICW P Sbjct: 314 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 373 Query: 268 YAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS------AVYNPVIYIMMNKQFRNCMVTTL 321 + Y FG + I FA S + NP+IY + +K R+ + Sbjct: 374 LLAIMVYDV------FGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF 427 Query: 322 --CCG-----KNPLGDDE 332 C G N +GD + Sbjct: 428 PSCEGTAQPLDNSMGDSD 445 >4BUO-A nrPDB Length = 335 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 17/240 (7%) Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM-SNFRFGENHAIMGV 157 +H + FG GC F ++V L++E Y+ +C P + + + Sbjct: 85 VHHPWAFGDAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFI 144 Query: 158 AFTWVMALACAAPPL-------VGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVV 210 + W+ + A P L + P G+ C+ +D T +F+ ++F Sbjct: 145 SAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLF-- 202 Query: 211 HFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAG 270 ++ I+ +L V +AA +A + ++ +VIAF++CWLPY Sbjct: 203 PMLVASILNTVIANKLTVMVHQAAFNMTIEPGRVQALRRGVLVLRAVVIAFVVCWLPYHV 262 Query: 271 VAF---YIFTHQGS----DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 YI Q + DF F + SA NP++Y +++ FR ++TL C Sbjct: 263 RRLMFCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTLAC 322 >3SN6-R nrPDB Length = 514 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 75/338 (22%), Positives = 137/338 (40%), Gaps = 54/338 (15%) Query: 29 YYLAEPWQFSM--LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 Y E W M + + + L I+ G N L + + ++L+T NY + +LA ADL M Sbjct: 175 YAADEVWVVGMGIVMSLIVLAIVFG---NVLVITAIAKFERLQTVTNYFITSLACADLVM 231 Query: 87 VFGGFTTTLYTSLH---GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM 143 G + + H + FG C L ++ +L V+A++RY + P Sbjct: 232 ---GLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPF 288 Query: 144 S-NFRFGENHAIMGVAFTWVMA-LACAAPPLVGWSRYI-PEGMQC----SCGIDYYTPHE 196 +N A + + W+++ L P + W R E + C +C D++T Sbjct: 289 KYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETC-CDFFT--- 344 Query: 197 ETNNESFVIYMFVVHFIIPLIVIFFCYGQL----------------VFTVKEAAAQQQES 240 N+++ I +V F +PL+++ F Y ++ F V+ + +Q+ Sbjct: 345 ---NQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDG 401 Query: 241 ATTQ----------KAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTI 290 T K K + + IIM F +CWLP+ V +++ + Sbjct: 402 RTGHGLRRSSKFCLKEHKALKTLGIIMG-TFTLCWLPFFIVNIVHVIQDNLIRKEVYILL 460 Query: 291 PAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 + ++ +NP+IY + FR LC ++ L Sbjct: 461 N-WIGYVNSGFNPLIYC-RSPDFRIAFQELLCLRRSSL 496 >2R4S-A nrPDB Length = 342 Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 74/334 (22%), Positives = 136/334 (40%), Gaps = 54/334 (16%) Query: 33 EPWQFSM--LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG 90 E W M + + + L I+ G N L + + ++L+T NY + +LA ADL M G Sbjct: 7 EVWVVGMGIVMSLIVLAIVFG---NVLVITAIAKFERLQTVTNYFITSLACADLVM---G 60 Query: 91 FTTTLYTSLH---GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NF 146 + + H + FG C L ++ +L V+A++RY + P Sbjct: 61 LAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS 120 Query: 147 RFGENHAIMGVAFTWVMA-LACAAPPLVGWSRYI-PEGMQC----SCGIDYYTPHEETNN 200 +N A + + W+++ L P + W R E + C +C D++T N Sbjct: 121 LLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETC-CDFFT------N 173 Query: 201 ESFVIYMFVVHFIIPLIVIFFCYGQLV----------------FTVKEAAAQQQESATTQ 244 +++ I +V F +PL+++ F Y ++ F V+ + +Q+ T Sbjct: 174 QAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGH 233 Query: 245 ----------KAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFF 294 K K + + IIM F +CWLP+ V +++ + + Sbjct: 234 GLRRSSKFCLKEHKALKTLGIIMG-TFTLCWLPFFIVNIVHVIQDNLIRKEVYILLN-WI 291 Query: 295 AKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 ++ +NP+IY + FR LC ++ L Sbjct: 292 GYVNSGFNPLIY-CRSPDFRIAFQELLCLRRSSL 324 >5WS3-A nrPDB Length = 560 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 35/167 (20%), Positives = 78/167 (46%), Gaps = 9/167 (5%) Query: 12 PFSNKTGVVRSPFEA---PQYYLAEPWQFSMLAAYM--FLLIMLGFPINFLTLYVTVQHK 66 PF N T F +Y + +++ ++A Y+ F++ ++G N L ++ Sbjct: 34 PFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIG---NVLVCVAVWKNH 90 Query: 67 KLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALW 126 +RT NY ++NL++AD+ + TL + + FG + C + + T+ +++ Sbjct: 91 HMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVL 150 Query: 127 SLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLV 173 +L +A++R+ +C P+ F+ A + W+++ P + Sbjct: 151 TLSCIALDRWYAICHPLM-FKSTAKRARNSIVIIWIVSCIIMIPQAI 196 Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 47/92 (51%), Gaps = 7/92 (7%) Query: 231 KEAAAQQQESATTQ-KAEKEVTRMVIIMVIAFLICWLPYA-----GVAFYIFTH-QGSDF 283 +E ++ S + Q +A ++ RM++++++ F IC+LP + F +F H + + Sbjct: 446 RENCKKRAMSFSKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFAHTEDRET 505 Query: 284 GPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 + T + ++ NP+IY ++ +FR Sbjct: 506 VYAWFTFSHWLVYANSAANPIIYNFLSGKFRE 537 >4XEE-A nrPDB Length = 541 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 62/263 (23%), Positives = 103/263 (39%), Gaps = 45/263 (17%) Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKP-MSNFRFGENHAIMGV 157 +H + FG GC F ++ L++ERY+ +C P + + + Sbjct: 99 VHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFI 158 Query: 158 AFTWVMALACAAPPL--VGWSRYI-----PEGMQCSCGIDYYTPHEETNNESFVIYMFVV 210 + W+ + A P L +G P G+ C+ +D T +F+ ++F Sbjct: 159 SAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLF-- 216 Query: 211 HFIIPLIVIFFCY----GQLVFTVKEAAAQQQ--ESATTQKAEKEVTRMVI--------- 255 P++VI +L V +AA Q + T E M I Sbjct: 217 ----PMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRVQALR 272 Query: 256 -------IMVIAFLICWLPYAGVAF---YIFTHQGSDF-----GPIFMTIPAFFAKTSAV 300 +VIAF++CWLPY YI Q + F +M A F +SA+ Sbjct: 273 HGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYASSAI 332 Query: 301 YNPVIYIMMNKQFRNCMVTTLCC 323 NP++Y +++ FR ++TL C Sbjct: 333 -NPILYNLVSANFRQVFLSTLAC 354 >4EJ4-A nrPDB Length = 461 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 44/189 (23%), Positives = 88/189 (46%), Gaps = 14/189 (7%) Query: 50 LGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFV----F 105 +G N L ++ V++ KL+T N + NLA+AD T+TL Y + F Sbjct: 27 VGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALA-----TSTLPFQSAKYLMETWPF 81 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGVAFTWVM 163 G C ++++L +++++RY+ VC P+ +FR ++ + WV+ Sbjct: 82 GELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICI-WVL 140 Query: 164 ALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCY 223 A P +V + P C + + +P + + I +F+ F++P+++I CY Sbjct: 141 ASGVGVPIMV-MAVTQPRDGAVVCMLQFPSPSWYWDTVT-KICVFLFAFVVPILIITVCY 198 Query: 224 GQLVFTVKE 232 G ++ ++ Sbjct: 199 GLMLLRLRS 207 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 10/94 (10%) Query: 244 QKAEKEVTRMVIIMVIAFLICWLPYA--GVAFYIFTHQGSD---FGPIFMTIPAFFAKTS 298 ++ + +TRMV+++V AF++CW P + + + D + + I +A +S Sbjct: 372 DRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSS 431 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDE 332 NPV+Y +++ F+ C LC + P G E Sbjct: 432 --LNPVLYAFLDENFKRCF-RQLC--RTPCGRQE 460 >6GPS-A nrPDB Length = 429 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 68/338 (20%), Positives = 127/338 (37%), Gaps = 65/338 (19%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT-SLHGYFV 104 L+ + GF N L + + + +KKL+ + LLNLA++DL + T L+ S +V Sbjct: 50 LVFIFGFVGNMLVVLILINYKKLKCLTDIYLLNLAISDLLFL---ITLPLWAHSAANEWV 106 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGV---AFTW 161 FG C L +G ++ +++L I+RY+ + + F GV TW Sbjct: 107 FGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAV--FALKARTVTFGVVTSVITW 164 Query: 162 VMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFF 221 ++A+ + P ++ +++ E CG Y P N + I ++ ++PL+++ Sbjct: 165 LVAVFASVPNII-FTKCQKEDSVYVCG--PYFPRGWNNFHT--IMRNILGLVLPLLIMVI 219 Query: 222 CYGQLVFTVKE-------------------------------------------AAAQQQ 238 CY ++ T+ Q Sbjct: 220 CYSGILKTLLRMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQF 279 Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVA--------FYIFTHQGSDFGPIFMTI 290 E +K R++ ++I + + W PY V F + + + + Sbjct: 280 EEVEEEKKRHRDVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQV 339 Query: 291 PAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 T NP+IY + ++FR+ L C PL Sbjct: 340 TETLGMTHCCINPIIYAFVGEEFRSLFHIALGCRIAPL 377 >4U15-A nrPDB Length = 418 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 18/160 (11%) Query: 35 WQ---FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF 91 WQ + L ++ L+ ++G N L + +K+L+T NY LL+LA ADL + G Sbjct: 10 WQVVFIAFLTGFLALVTIIG---NILVIVAFKVNKQLKTVNNYFLLSLACADL--IIGVI 64 Query: 92 TTTLYTS--LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG 149 + L+T+ + + G C+L + ++ +L+V++ +RY + +P++ +R Sbjct: 65 SMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLT-YRAK 123 Query: 150 ENHAIMGV--AFTWVMALACAAPPLVGW-----SRYIPEG 182 GV WV++ AP ++ W R +P G Sbjct: 124 RTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPG 163 Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIY 306 EK+ + + +++AF+I W PY + + T S + + + ++ NPV Y Sbjct: 326 EKKAAQTLSAILLAFIITWTPY-NIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCY 384 Query: 307 IMMNKQFRNCMVTTLCC 323 + NK FR T L C Sbjct: 385 ALCNKTFRTTFKTLLLC 401 >4U14-A nrPDB Length = 460 Score = 51.2 bits (121), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 18/160 (11%) Query: 35 WQ---FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF 91 WQ + L ++ L+ ++G N L + +K+L+T NY LL+LA ADL + G Sbjct: 10 WQVVFIAFLTGFLALVTIIG---NILVIVAFKVNKQLKTVNNYFLLSLACADL--IIGVI 64 Query: 92 TTTLYTS--LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG 149 + L+T+ + + G C+L + ++ +L+V++ +RY + +P++ +R Sbjct: 65 SMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLT-YRAK 123 Query: 150 ENHAIMGV--AFTWVMALACAAPPLVGW-----SRYIPEG 182 GV WV++ AP ++ W R +P G Sbjct: 124 RTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPG 163 Score = 35.8 bits (81), Expect = 0.026, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIY 306 EK+ + + +++AF+I W PY + + T S + + + ++ NPV Y Sbjct: 369 EKKAAQTLSAILLAFIITWTPY-NIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCY 427 Query: 307 IMMNKQFRNCMVTTLCC 323 + NK FR T L C Sbjct: 428 ALCNKTFRTTFKTLLLC 444 >6HLP-A nrPDB Length = 520 Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 4/209 (1%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 P ++ WQ + AA ++++ N + +++ + HK++RT NY L+N A A+ M Sbjct: 22 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNAAFAEASM 81 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 ++H + +G C FF +++S+ +A +RY+ + P+ Sbjct: 82 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAIFASIYSMTAVAFDRYMAIIHPLQP- 140 Query: 147 RFGENHAIMGVAFTWVMALACAAPP-LVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI 205 R + + WV+AL A P + +P + C I++ + + + I Sbjct: 141 RLSLTATKVVICVIWVLALLLAFPQGYYSTTETMPS--RVVCKIEWPEHPNKIYEKVYHI 198 Query: 206 YMFVVHFIIPLIVIFFCYGQLVFTVKEAA 234 + V+ + +PL+VI + Y + T++ + Sbjct: 199 CVTVLIYFLPLLVIGYLYTVVGITLRASG 227 Score = 34.3 bits (77), Expect = 0.074, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 9/60 (15%) Query: 261 FLICWLPYAGVAFYIFTHQGSDF------GPIFMTIPAFFAKTSAVYNPVIYIMMNKQFR 314 F ICWLP+ F++ + D +++ I + A +S +YNP+IY +N +FR Sbjct: 442 FAICWLPFH--IFFLLPYINPDLYLKKFIQQVYLAI-MWLAMSSTMYNPIIYCCLNDRFR 498 >5VBL-B nrPDB Length = 407 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 72/348 (20%), Positives = 136/348 (39%), Gaps = 61/348 (17%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQH-KKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 +++ A L+ +LG N L L+ + ++ R + + +LAVADL V Y Sbjct: 47 ALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATY 106 Query: 97 TSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIM 155 T + FG C L + + + + L L+ +RY+ + +P++N R + Sbjct: 107 TYRDYDWPFGTFFCKLSSYLIFVNMYASAFCLTGLSFDRYLAIVRPVANARLRLRVSGAV 166 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEGM-QCSCGIDYYTPHEETNNESFVIYMFV----V 210 A WV+A A P +V + E + C +DY ++ ++ + + V V Sbjct: 167 ATAVLWVLAALLAMPVMVLRTTGDLENTNKVQCYMDYSMVATVSSEWAWEVGLGVSSTTV 226 Query: 211 HFIIPLIVIFFCYGQLVFTVKEAAAQQQESAT---------------------------- 242 F++P ++ CY F + + A ++ + T Sbjct: 227 GFVVPFTIMLTCY----FFIAQTIAMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPD 282 Query: 243 -----------TQKAEKEVTR----MVIIMVIAFLICWLPYAGV-AFYI---FTHQGSDF 283 Q E E R +++++V+ F +C +PY V Y+ H DF Sbjct: 283 DWVCPLCGVGKDQFEEVEERRRLLSIIVVLVVTFALCKMPYHLVKTLYMLGSLLHWPCDF 342 Query: 284 GPIFMTIPAF---FAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 M I + + ++ NP +Y + +FR + L G++ L Sbjct: 343 DLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLLMGQSRL 390 >6DRY-A nrPDB Length = 411 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/211 (21%), Positives = 96/211 (45%), Gaps = 24/211 (11%) Query: 45 FLLIMLGFPI---NFLTLYVTVQHKKLRTPLNYILLNLAVAD----LFMVFGGFTTTLYT 97 L++M+ P N L + KKL+ NY L++LAVAD LF++ T ++ Sbjct: 24 LLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFE 83 Query: 98 SLHGY-FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENH-AIM 155 ++ V P L+ F+T ++W L ++++RY+ + KP+ ++ A + Sbjct: 84 AMWPLPLVLCPAWLFLDVLFST----ASIWHLCAISVDRYIAIKKPIQANQYNSRATAFI 139 Query: 156 GVAFTWVMALACAAP-PLVGWSRYI--PEGMQCSCGIDYYTPHEETNNESFVIYMFVVHF 212 + W++++ A P P+ G + P + C + + F+++ + F Sbjct: 140 KITVVWLISIGIAIPVPIKGIETDVDNPNNITCVLTKERFG--------DFMLFGSLAAF 191 Query: 213 IIPLIVIFFCYGQLVFTVKEAAAQQQESATT 243 PL ++ Y + +++ AA +++ T Sbjct: 192 FTPLAIMIVTYFLTIHALQKKAADLEDNWET 222 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 14/109 (12%) Query: 230 VKEAAAQQQESATTQKA------------EKEVTRMVIIMVIAFLICWLPY--AGVAFYI 275 VKEA A ++ TT+ A E+ ++++ I+ FL+ W P+ + + Sbjct: 297 VKEAQAAAEQLKTTRNAYIQKYLVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVL 356 Query: 276 FTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCG 324 + + I + S+ NP++Y + NK FR+ + C Sbjct: 357 CDSCNQTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCN 405 >5LWE-A nrPDB Length = 331 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 69/297 (23%), Positives = 126/297 (42%), Gaps = 40/297 (13%) Query: 45 FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL---YTSLHG 101 +L+ ++G N L + V + +T + LLNLA+ADL F TL + Sbjct: 34 WLVFIVGALGNSLVILVYWYCARAKTATDMFLLNLAIADLL-----FLVTLPFWAIAAAD 88 Query: 102 YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMG--VAF 159 + F C + + + ++ + ++RY+ + + M + E + V F Sbjct: 89 QWKFQTFMCKVVNSMYKMNFYSCVLLIMCICVDRYIAIAQAMRAHTWREKRLLYSKMVCF 148 Query: 160 T-WVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVV-HFIIPLI 217 T WV+A A P ++ +S+ E C + Y E T +S V+ + V+ F +P + Sbjct: 149 TIWVLAAALCIPEIL-YSQIKEESGIAICTM-VYPSDESTKLKSAVLALKVILGFFLPFV 206 Query: 218 VIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFT 277 V+ CY ++ T+ +A + A + I ++ F++ PY I Sbjct: 207 VMACCYTIIIHTLIQAKKSSKHKA---------LKATITVLTVFVLSQFPYNC----ILL 253 Query: 278 HQGSDFGPIFMT-------IPAFFAKTSAV------YNPVIYIMMNKQFRNCMVTTL 321 Q D +F++ I F T A+ NPV+Y+ + ++FR +V TL Sbjct: 254 VQTIDAYAMFISNCAVSTAIDICFQVTQAIAFFHSCLNPVLYVFVGERFRRDLVKTL 310 >3P0G-A nrPDB Length = 501 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 25/212 (11%) Query: 33 EPWQFSM--LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG 90 E W M + + + L I+ G N L + + ++L+T NY + +LA ADL M G Sbjct: 38 EVWVVGMGIVMSLIVLAIVFG---NVLVITAIAKFERLQTVTNYFITSLACADLVM---G 91 Query: 91 FTTTLYTSLH---GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NF 146 + + H + FG C L ++ +L V+A++RY + P Sbjct: 92 LAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS 151 Query: 147 RFGENHAIMGVAFTWVMA-LACAAPPLVGWSRYI-PEGMQC----SCGIDYYTPHEETNN 200 +N A + + W+++ L P + W R E + C +C D++T N Sbjct: 152 LLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETC-CDFFT------N 204 Query: 201 ESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKE 232 +++ I +V F +PL+++ F Y ++ K Sbjct: 205 QAYAIASSIVSFYVPLVIMVFVYSRVFQEAKR 236 >6GPX-A nrPDB Length = 349 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 64/325 (19%), Positives = 123/325 (37%), Gaps = 65/325 (20%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT-SLHGYFV 104 L+ + GF N L + + + +KKL+ + LLNLA++DL + T L+ S +V Sbjct: 23 LVFIFGFVGNMLVVLILINYKKLKCLTDIYLLNLAISDLLFL---ITLPLWAHSAANEWV 79 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGV---AFTW 161 FG C L +G ++ +++L I+RY+ + + F GV TW Sbjct: 80 FGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAV--FALKARTVTFGVVTSVITW 137 Query: 162 VMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFF 221 ++A+ + P ++ +++ E CG Y P N + I ++ ++PL+++ Sbjct: 138 LVAVFASVPNII-FTKCQKEDSVYVCG--PYFPRGWNNFHT--IMRNILGLVLPLLIMVI 192 Query: 222 CYGQLVFTVKE-------------------------------------------AAAQQQ 238 CY ++ T+ Q Sbjct: 193 CYSGILKTLLRMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQF 252 Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVA--------FYIFTHQGSDFGPIFMTI 290 E +K R++ ++I + + W PY V F + + + + Sbjct: 253 EEVEEEKKRHRDVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQV 312 Query: 291 PAFFAKTSAVYNPVIYIMMNKQFRN 315 T NP+IY + ++FR+ Sbjct: 313 TETLGMTHCCINPIIYAFVGEKFRS 337 >6DO1-A nrPDB Length = 425 Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 50/240 (20%), Positives = 101/240 (42%), Gaps = 2/240 (0%) Query: 14 SNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLN 73 S + G+ R + P+ + F M+ ++ ++G N L + V + KL+T + Sbjct: 13 STEDGIKRIQDDCPKAG-RHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVAS 71 Query: 74 YILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAI 133 LLNLA+ADL + +YT++ + FG C + + +++ L L+I Sbjct: 72 VFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSI 131 Query: 134 ERYVVVCKPM-SNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYY 192 +RY+ + PM S R A + W++A + P ++ + + E + +Y Sbjct: 132 DRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHY 191 Query: 193 TPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 T + ++ F+ P ++I Y + +K+A + T K + + Sbjct: 192 ESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYDLEDNWETLNDNLKVIEK 251 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 16/102 (15%) Query: 230 VKEAAAQQQESATTQKAE--------KEVTRMVIIMVIAFLICWLPYAGVAFY------- 274 VKEA A ++ TT+ AE ++ ++++ +V+ F W+P+ F Sbjct: 316 VKEAQAAAEQLKTTRNAEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLG 375 Query: 275 -IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 I + +D M I A + NP+ Y + K+F+ Sbjct: 376 IIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 417 >4XT3-A nrPDB Length = 362 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 65/277 (23%), Positives = 108/277 (38%), Gaps = 43/277 (15%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGP----TGC 110 NFL ++ ++++ + +NLA ADL V Y H P T C Sbjct: 59 NFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNSLASVPCTLLTAC 118 Query: 111 NLEGFFATLG--GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACA 168 FA+L EIAL + RY +P+ A + F W+ A+ A Sbjct: 119 FYVAMFASLCFITEIALDRYYAIVYMRY----RPV-------KQACLFSIFWWIFAVIIA 167 Query: 169 APPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVF 228 P + ++ + QC DY E + + + + F+IPL VI +CY ++ Sbjct: 168 IPHFMVVTK---KDNQCMTDYDYL---EVSYPIILNVELMLGAFVIPLSVISYCYYRISR 221 Query: 229 TVKEAAAQQQESATTQKAEK-EVTRMVIIMVIAFLICWLPYAGVAF------YIFTHQGS 281 V A +Q K + R++I +V+ F+I WLPY F + Sbjct: 222 IV----------AVSQSRHKGRIVRVLIAVVLVFIIFWLPYHLTLFVDTLKLLKWISSSC 271 Query: 282 DFGPIF---MTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 +F + + A NP++Y+ + +FR Sbjct: 272 EFERSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQ 308 >5WB1-A nrPDB Length = 458 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 54/220 (24%), Positives = 91/220 (41%), Gaps = 32/220 (14%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGP----TGC 110 NFL ++ ++++ + +NLA ADL V Y H P T C Sbjct: 59 NFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNSLASVPCTLLTAC 118 Query: 111 NLEGFFATLG--GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACA 168 FA+L EIAL + RY +P+ A + F W+ A+ A Sbjct: 119 FYVAMFASLCFITEIALDRYYAIVYMRY----RPV-------KQACLFSIFWWIFAVIIA 167 Query: 169 APPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVF 228 P + ++ + QC DY E + + + + F+IPL VI +CY ++ Sbjct: 168 IPHFMVVTK---KDNQCMTDYDYL---EVSYPIILNVELMLGAFVIPLSVISYCYYRISR 221 Query: 229 TVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPY 268 V + + + + + R++I +V+ F+I WLPY Sbjct: 222 IV---------AVSQSRHKGRIVRVLIAVVLVFIIFWLPY 252 >5WIV-A nrPDB Length = 422 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 14/108 (12%) Query: 230 VKEAAAQQQESATTQKA------------EKEVTRMVIIMVIAFLICWLPYAGVAFYIFT 277 VKEA A ++ TT+ A E++ R++ ++V AFL+CW P+ V Sbjct: 315 VKEAQAAAEQLKTTRNAYIQKYLAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQAL 374 Query: 278 HQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL--CC 323 P ++ + ++ NPVIY + N +FRN L CC Sbjct: 375 CPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC 422 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 40/184 (21%), Positives = 79/184 (42%), Gaps = 20/184 (10%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLH-GYFV 104 LLI N L + L+TP N +++LA ADL + +Y+ + G ++ Sbjct: 47 LLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWL 106 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVM 163 P C+ + ++++L ++++R+V V P+ N + G ++ + TW++ Sbjct: 107 LSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLL 166 Query: 164 ALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE----ETNNESFVIYMFVVHFIIPLIVI 219 + A AAP L CG++ + + +V+Y V F +P ++ Sbjct: 167 SAAVAAPVL--------------CGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLM 212 Query: 220 FFCY 223 Y Sbjct: 213 LLLY 216 >3RZE-A nrPDB Length = 452 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 39/189 (20%), Positives = 86/189 (45%), Gaps = 23/189 (12%) Query: 54 INFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLE 113 +N L LY +KL T N +++L+VADL + + L + G C Sbjct: 25 LNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFW 84 Query: 114 GFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF----GENHAIMG---VAFTWVMALA 166 + +++S+ +L I+RY V +P+ ++ + I+G ++F WV+ Sbjct: 85 LSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVI--- 141 Query: 167 CAAPPLVGWSRYIPE---GMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCY 223 P++GW+ ++ + + C D+Y + F + +++F +P +++ + Y Sbjct: 142 ----PILGWNHFMQQTSVRREDKCETDFY------DVTWFKVMTAIINFYLPTLLMLWFY 191 Query: 224 GQLVFTVKE 232 ++ V++ Sbjct: 192 AKIYKAVRQ 200 Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust. Identities = 14/69 (20%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIY 306 E++ + + ++ AF++CW+PY + F + + + ++ NP+IY Sbjct: 368 ERKAAKQLGFIMAAFILCWIPYF-IFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIY 426 Query: 307 IMMNKQFRN 315 + N+ F+ Sbjct: 427 PLCNENFKK 435 >4Z36-A nrPDB Length = 459 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 14/146 (9%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 + IML N L + +++ P+ Y++ NLA AD F F T + + Sbjct: 79 IFIMLA---NLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLT 135 Query: 106 GPTGCNLEGFFAT-LGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMA 164 T +G T L +A +L+ +AIER++ V + + R ++ + W MA Sbjct: 136 VSTWLLRQGLIDTSLTASVA--NLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMA 193 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGID 190 + A P VGW+ C C I+ Sbjct: 194 IVMGAIPSVGWN--------CICDIE 211 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 18/97 (18%) Query: 230 VKEAAAQQQESATTQKA--EK---------EVTRMVIIMVIAFLICWLPYAGVAFYIFTH 278 VKEA A ++ TT+ A +K + + V+I++ AF+ICW P + Sbjct: 329 VKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDCCC 388 Query: 279 QGSD---FGPIFMTIPAFFAKTSAVYNPVIYIMMNKQ 312 D + F+ + F ++ NP+IY +K+ Sbjct: 389 PQCDVLAYEKFFLLLAEF----NSAMNPIIYSYRDKE 421 >5XSZ-A nrPDB Length = 477 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/201 (23%), Positives = 92/201 (45%), Gaps = 12/201 (5%) Query: 37 FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 +SM+ + +F M+G N +Y+ + KLR ++NL V+DL V ++ Sbjct: 31 YSMVFSIVF---MVGLITNVAAMYIFMCSLKLRNETTTYMMNLVVSDLLFVL-TLPLRVF 86 Query: 97 TSLHGYFVFGPTGCNLEG--FFATLGGEIALWSLVVLAIERYVVVCKPMSN--FRFGENH 152 + + FG C L F+ + G I L ++++R++ + P + R N Sbjct: 87 YFVQQNWPFGSLLCKLSVSLFYTNMYGSILF--LTCISVDRFLAIVYPFRSRGLRTKRNA 144 Query: 153 AIMGVAFTWVMALACAAPP-LVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVH 211 I+ A WV+ L+ + P + S E SC ++ + +++ VI++ V Sbjct: 145 KIVCAA-VWVLVLSGSLPTGFMLNSTNKLENNSISCFENFSSKEWKSHLSKVVIFIETVG 203 Query: 212 FIIPLIVIFFCYGQLVFTVKE 232 F+IPL++ C ++ T++ Sbjct: 204 FLIPLMLNVVCSAMVLQTLRR 224 Score = 27.7 bits (60), Expect = 8.7, Method: Compositional matrix adjust. Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 8/77 (10%) Query: 247 EKEVTRMVIIMVIAFLICWLPY-AGVAFYIF----THQGSDFGPIFMT---IPAFFAKTS 298 +K++ RM+I+ + F C++PY + FY T +G + T I A ++ Sbjct: 391 KKKILRMIIVHLFIFCFCFIPYNVNLVFYSLVRTNTLKGCAAESVVRTIYPIALCIAVSN 450 Query: 299 AVYNPVIYIMMNKQFRN 315 ++P++Y ++ +N Sbjct: 451 CCFDPIVYYFTSETIQN 467 >5U09-A nrPDB Length = 508 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 46/173 (26%), Positives = 83/173 (47%), Gaps = 21/173 (12%) Query: 55 NFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLE 113 N L L V + + LR P + + +LAVADL G +Y+ + + N+ Sbjct: 46 NLLVLCVILHSRSLRCRPSYHFIGSLAVADLL----GSVIFVYSFIDFHVFHRKDSRNV- 100 Query: 114 GFFATLGGEIA-----LWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALAC 167 F LGG A + SL + AI+RY+ + +P++ R A++ W +A+ Sbjct: 101 -FLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVI 159 Query: 168 AAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIF 220 A PL+GW+ E +Q C D + PH +E+++++ V ++ L +++ Sbjct: 160 AVLPLLGWN---CEKLQSVCS-DIF-PH---IDETYLMFWIGVTSVLLLFIVY 204 >5T1A-A nrPDB Length = 508 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 46/182 (25%), Positives = 85/182 (46%), Gaps = 14/182 (7%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT-SLHGYFV 104 L+ + GF N L + + + KKL+ + LLNLA++DL + T L+ S +V Sbjct: 61 LVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFL---ITLPLWAHSAANEWV 117 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGV---AFTW 161 FG C L +G ++ +++L I+RY+ + + F GV TW Sbjct: 118 FGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAV--FALKARTVTFGVVTSVITW 175 Query: 162 VMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFF 221 ++A+ + P ++ +++ E CG Y P N + I ++ ++PL+++ Sbjct: 176 LVAVFASVPGII-FTKCQKEDSVYVCGP--YFPRGWNNFHT--IMRNILGLVLPLLIMVI 230 Query: 222 CY 223 CY Sbjct: 231 CY 232 >4ZJC-A nrPDB Length = 553 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 26/116 (22%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEG 114 N L ++ +RT NY ++NL++AD+ + +L + ++FG C + Sbjct: 72 NTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIP 131 Query: 115 FFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAP 170 + + +A+ +L +A++R+ +C P+ F+ A + W ++LA P Sbjct: 132 YLQAVSVSVAVLTLSFIALDRWYAICHPLL-FKSTARRARGSILGIWAVSLAIMVP 186 Score = 35.0 bits (79), Expect = 0.044, Method: Compositional matrix adjust. Identities = 21/100 (21%), Positives = 49/100 (49%), Gaps = 7/100 (7%) Query: 231 KEAAAQQQESATTQ-KAEKEVTRMVIIMVIAFLICWLPYA--GVAFYIFT--HQGSDFGP 285 +E ++ S + Q +A ++ +M++++++ F +C+LP + + +F Q SD Sbjct: 439 RENCKKRAMSFSKQMRARRKTAKMLMVVLLVFALCYLPISVLNILKRVFGMFRQASDREA 498 Query: 286 IF--MTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 ++ T + ++ NP+IY ++ +FR C Sbjct: 499 VYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 538 >2LNL-A nrPDB Length = 309 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 25/225 (11%) Query: 103 FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAF-TW 161 ++FG C + + + L ++++RY+ + + H + V W Sbjct: 84 WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLT-QKRHLVKFVCLGCW 142 Query: 162 VMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMF--VVHFIIPLIVI 219 +++ + P + Y P C Y +T V+ + FI+PL V+ Sbjct: 143 GLSMNLSLPFFLFRQAYHPNNSSPVC---YEVLGNDTAKWRMVLRILPHTFGFIVPLFVM 199 Query: 220 FFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAF------ 273 FCYG + T+ +A Q+ A R++ +V+ FL+CWLPY V Sbjct: 200 LFCYGFTLRTLFKAHMGQKHRAM---------RVIFAVVLIFLLCWLPYNLVLLADTLMR 250 Query: 274 -YIFTHQGSDFGPIFMTIPA--FFAKTSAVYNPVIYIMMNKQFRN 315 + I + A + NP+IY + + FR+ Sbjct: 251 TQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRH 295 >5GLI-A nrPDB Length = 464 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 44/184 (23%), Positives = 75/184 (40%), Gaps = 6/184 (3%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 L+ +LG N LY+ ++K +R N ++ +LA+ DL + +Y L + F Sbjct: 48 LVFVLGIIGNSTLLYIIYKNKCMRNGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPF 107 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMA 164 G C L F I + SL L+I+RY V G + + WV++ Sbjct: 108 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 167 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI-----YMFVVHFIIPLIVI 219 + A P +G+ + I P ++T F ++F +F +PL + Sbjct: 168 VVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYATAKDWWLFSFYFCLPLAIT 227 Query: 220 FFCY 223 F Y Sbjct: 228 AFFY 231 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%) Query: 245 KAEKEVTRMVIIMVIAFLICWLP--YAGVAFYIFTHQGS-------DFGPIFMTIPAFFA 295 K +EV + V +V+ F +CWLP A + +Q F + I A Sbjct: 364 KQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDPNRCELLSFLLVLDYIGINMA 423 Query: 296 KTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 ++ NP+ +++K+F+N + LCC Sbjct: 424 SLNSCANPIALYLVSKRFKNAFKSALCC 451 >5GLH-A nrPDB Length = 498 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 44/184 (23%), Positives = 75/184 (40%), Gaps = 6/184 (3%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 L+ +LG N LY+ ++K +R N ++ +LA+ DL + +Y L + F Sbjct: 48 LVFVLGIIGNSTLLYIIYKNKCMRNGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPF 107 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMA 164 G C L F I + SL L+I+RY V G + + WV++ Sbjct: 108 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 167 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI-----YMFVVHFIIPLIVI 219 + A P +G+ + I P ++T F ++F +F +PL + Sbjct: 168 VVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYATAKDWWLFSFYFCLPLAIT 227 Query: 220 FFCY 223 F Y Sbjct: 228 AFFY 231 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%) Query: 245 KAEKEVTRMVIIMVIAFLICWLP--YAGVAFYIFTHQGS-------DFGPIFMTIPAFFA 295 K +EV + V +V+ F +CWLP A + +Q F + I A Sbjct: 407 KQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDPNRCELLSFLLVLDYIGINMA 466 Query: 296 KTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 ++ NP+ +++K+F+N + LCC Sbjct: 467 SLNSCANPIALYLVSKRFKNAFKSALCC 494 >5XRA-A nrPDB Length = 438 Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 20/176 (11%) Query: 55 NFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLE 113 N L L V + + LR P + + +LAVADL G +Y+ + + N+ Sbjct: 36 NLLVLCVILHSRSLRCRPSYHFIGSLAVADLL----GSVIFVYSFIDFHVFHRKDSRNV- 90 Query: 114 GFFATLGGEIA-----LWSLVVLAIERYVVVCKPMSNFRFGEN-HAIMGVAFTWVMALAC 167 F LGG A + SL + AI+RY+ + +P++ R A++ W +A+ Sbjct: 91 -FLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVI 149 Query: 168 AAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCY 223 A PL+GW+ E +Q C D + PH + + ++ VV ++ IV + Y Sbjct: 150 AVLPLLGWN---CEKLQSVCS-DIF-PH--IDKTYLMFWIGVVSVLLLFIVYAYMY 198 >5UVI-A nrPDB Length = 447 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/218 (21%), Positives = 91/218 (41%), Gaps = 38/218 (17%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 +L +LG N L + + L+ NY +++LA AD+ G ++ F Sbjct: 43 VLAILG---NVLVCWAVWLNSNLQNVTNYFVVSLAAADI--AVGVLAIPFAITISTGFCA 97 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMA 164 GC F + + +++SL+ +AI+RY+ + P+ N A +A WV++ Sbjct: 98 ACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLS 157 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNN-------------ESFVIYMFVVH 211 A P++GW+ +CG P E N+ E V ++V+ Sbjct: 158 FAIGLTPMLGWN---------NCG----QPKEGKNHSQGCGEGQVACLFEDVVPMNYMVY 204 Query: 212 F------IIPLIVIFFCYGQLVFTVKEAAAQQQESATT 243 F ++PL+++ Y ++ + A +++ T Sbjct: 205 FNFFACVLVPLLLMLGVYLRIFLAARRQLADLEDNWET 242 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 16/102 (15%) Query: 230 VKEAAAQQQESATTQKA-------------EKEV--TRMVIIMVIAFLICWLPYAGVAFY 274 VKEA A ++ TT+ A +KEV + + I+V F +CWLP + + Sbjct: 317 VKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCF 376 Query: 275 IFTHQGSDFGPIF-MTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 F P++ M + + T++V NP IY ++FR Sbjct: 377 TFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ 418 >4GRV-A nrPDB Length = 510 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 7/74 (9%) Query: 257 MVIAFLICWLPYAGVAF---YIFTHQGS----DFGPIFMTIPAFFAKTSAVYNPVIYIMM 309 +VIAF++CWLPY YI Q + DF F + A S+ NP++Y ++ Sbjct: 414 VVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALAYASSAINPILYNLV 473 Query: 310 NKQFRNCMVTTLCC 323 + FR ++TL C Sbjct: 474 SANFRQVFLSTLAC 487 >5WF6-A nrPDB Length = 504 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 +L +LG N L + + L+ NY +++LA AD+ G ++ F Sbjct: 49 VLAILG---NVLVCWAVWLNSNLQNVTNYFVVSLAAADI--AVGVLAIPFAITISTGFCA 103 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMA 164 GC F + + A++SL+ +AI+RY+ + P+ N A +A WV++ Sbjct: 104 ACHGCLFIACFVLVLTQSAIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLS 163 Query: 165 LACAAPPLVGWS 176 A P++GW+ Sbjct: 164 FAIGLTPMLGWN 175 Score = 35.0 bits (79), Expect = 0.051, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 1/75 (1%) Query: 242 TTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIF-MTIPAFFAKTSAV 300 +T + E + + I+V F +CWLP + + F P++ M + + T++V Sbjct: 401 STLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSV 460 Query: 301 YNPVIYIMMNKQFRN 315 NP IY ++FR Sbjct: 461 VNPFIYAYRIREFRQ 475 >3V2Y-A nrPDB Length = 520 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 24/176 (13%) Query: 55 NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNL-E 113 N L + KK P+ Y + NLA++DL + +T L S + P L E Sbjct: 81 NIFVLLTIWKTKKFHRPMYYFIGNLALSDL-LAGVAYTANLLLSGATTYKLTPAQWFLRE 139 Query: 114 G-FFATLGGEIALWSLVVLAIERYVVVCK-----PMSNFRFGENHAIMGVAFTWVMALAC 167 G F L + +SL+ +AIERY+ + K +NFR + ++ WV++L Sbjct: 140 GSMFVALSASV--FSLLAIAIERYITMLKMKLHNGSNNFRL-----FLLISACWVISLIL 192 Query: 168 AAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPL-IVIFFC 222 P++GW+ I CS + Y H ++++ V ++ L IVI +C Sbjct: 193 GGLPIMGWN-CISALSSCSTVLPLYHKH-------YILFCTTVFTLLLLSIVILYC 240 Score = 27.3 bits (59), Expect = 8.8, Method: Compositional matrix adjust. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 15/86 (17%) Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFF------ 294 A+ + + VII++ F+ CW P +F D G T F Sbjct: 410 ASRSSENVALLKTVIIVLSVFIACWAP-------LFILLLLDVGCKVKTCDILFRAEYFL 462 Query: 295 --AKTSAVYNPVIYIMMNKQFRNCMV 318 A ++ NP+IY + NK+ R + Sbjct: 463 VLAVLNSGTNPIIYTLTNKEMRRAFI 488 >5XJM-A nrPDB Length = 422 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 80/180 (44%), Gaps = 1/180 (0%) Query: 45 FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFV 104 +++ ++GF +N + + + K + + + NLAVADL ++ Y S ++ Sbjct: 19 YIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWL 78 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMA 164 FGP C + G F TL +++ + ++++RY V P + R A V W MA Sbjct: 79 FGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMA 138 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMF-VVHFIIPLIVIFFCY 223 + P E + + I + P + + + M ++ FIIPLI I CY Sbjct: 139 CLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCY 198 Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 11/56 (19%) Query: 229 TVKEAAAQQQESATTQKA-----------EKEVTRMVIIMVIAFLICWLPYAGVAF 273 VKEA A ++ TT+ A +V +M +V+AF+ICWLP+ + F Sbjct: 292 KVKEAQAAAEQLKTTRNAYIQKYLKNRITRDQVLKMAAAVVLAFIICWLPFHVLTF 347 >4NTJ-A nrPDB Length = 466 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 21/115 (18%) Query: 230 VKEAAAQQQESATTQKA-------------EKEVTRMVIIMVIAFLICWLPYAGVAFYIF 276 VKEA A ++ TT+ A K+V V I++ F IC++P+ Sbjct: 316 VKEAQAAAEQLKTTRNAYIQKYLRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYT 375 Query: 277 THQGSDFGPIFMTIPAFFAKTSAVY--------NPVIYIMMNKQFRNCMVTTLCC 323 Q D F+ K S ++ NP IY + K FRN +++ L C Sbjct: 376 LSQTRDVFDCTAENTLFYVKESTLWLTSLNACLNPFIYFFLCKSFRNSLISMLKC 430 >5NJ6-A nrPDB Length = 437 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 9/147 (6%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHG-YFV 104 ++ ++ P N + L+V + K + P + NLA+ADL V F + +HG ++ Sbjct: 31 IVFVVALPSNGMALWVFLFRTKKKAPAVIYMANLALADLLSVI-WFPLKIAYHIHGNNWI 89 Query: 105 FGPTGCN-LEGFF-ATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFT-W 161 +G CN L GFF A + I L L+++R + PM + R N AI G++ W Sbjct: 90 YGEALCNVLIGFFYANMYCSILF--LTCLSVQRAWEIVNPMGHSRKKANIAI-GISLAIW 146 Query: 162 VMALACAAPP-LVGWSRYIPEGMQCSC 187 ++ L P +V + +IP +C Sbjct: 147 LLILLVTIPLYVVKQTIFIPALQITTC 173 Score = 31.2 bits (69), Expect = 0.76, Method: Compositional matrix adjust. Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 15/109 (13%) Query: 230 VKEAAAQQQESATT------------QKAEKEVTRMVIIMVIAFLICWLP---YAGVAFY 274 VKEA A ++ TT +K K ++ + + +LIC+ P V ++ Sbjct: 300 VKEAQAAAEQLKTTRNAYIQKYLENSEKKRKRAIKLAVTVAAMYLICFTPSNLLLVVHYF 359 Query: 275 IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 + QG + + ++ +P +Y ++ FR+ L C Sbjct: 360 LIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLC 408 >5NDD-A nrPDB Length = 619 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 9/147 (6%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHG-YFV 104 ++ ++ P N + L+V + K + P + NLA+ADL V F + +HG ++ Sbjct: 213 IVFVVALPSNGMALWVFLFRTKKKAPAVIYMANLALADLLSVI-WFPLKIAYHIHGNNWI 271 Query: 105 FGPTGCN-LEGFF-ATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFT-W 161 +G CN L GFF A + I L L+++R + PM + R N AI G++ W Sbjct: 272 YGEALCNVLIGFFYANMYCSILF--LTCLSVQRAWEIVNPMGHSRKKANIAI-GISLAIW 328 Query: 162 VMALACAAPP-LVGWSRYIPEGMQCSC 187 ++ L P +V + +IP +C Sbjct: 329 LLILLVTIPLYVVKQTIFIPALQITTC 355 Score = 30.8 bits (68), Expect = 0.86, Method: Compositional matrix adjust. Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 15/109 (13%) Query: 230 VKEAAAQQQESATT------------QKAEKEVTRMVIIMVIAFLICWLP---YAGVAFY 274 VKEA A ++ TT +K K ++ + + +LIC+ P V ++ Sbjct: 482 VKEAQAAAEQLKTTRNAYIQKYLENSEKKRKRAIKLAVTVAAMYLICFTPSNLLLVVHYF 541 Query: 275 IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 + QG + + ++ +P +Y ++ FR+ L C Sbjct: 542 LIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLC 590 >5N2S-A nrPDB Length = 436 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 59/312 (18%), Positives = 120/312 (38%), Gaps = 38/312 (12%) Query: 28 QYYLAEPWQFSMLAAYM---FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 Q YLA + AAY+ L+ ++ P N L ++ ++ LR +++LAVAD+ Sbjct: 105 QKYLASSIS-AFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADV 163 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPT----GCNLEGFFATLGGEIALWSLVVLAIERYVVVC 140 + G L ++ GP C + + + ++ +L+ +A++RY+ V Sbjct: 164 LV--GALVIPLAILIN----IGPQTYFHTCLMVACPVLILAQSSILALLAIAVDRYLRVK 217 Query: 141 KPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETN 199 P+ A + +A W+++ P+ GW+ + P + Sbjct: 218 IPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAAAGSMGEPVIKCE 277 Query: 200 NESFVIYMFVVHFIIPLIVIFFCYGQL-----------VFTVKEAAAQQQESATTQKAEK 248 E + ++V+F FF + VF + ++ SA++ +K Sbjct: 278 FEKVISMEYMVYF------NFFVWVLPPLLLMVLIYLEVFALIRKQLNKKVSASSGDPQK 331 Query: 249 ------EVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYN 302 ++ + ++ F + WLP + I I F A ++ N Sbjct: 332 YYGKELKIAKSAALIAFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLAHGNSAMN 391 Query: 303 PVIYIMMNKQFR 314 P++Y ++FR Sbjct: 392 PIVYAFRIQKFR 403 >3VW7-A nrPDB Length = 484 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 54/224 (24%), Positives = 96/224 (42%), Gaps = 26/224 (11%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD- 83 E YL W + + + ++ P+N + + V + K++ P +L+LA AD Sbjct: 8 EDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADV 67 Query: 84 LFMVFGGFTTTLYTSLHGYFVFGPTGCNL--EGFFATLGGEIALWSLVVLAIERYVVVCK 141 LF+ F + Y S + FG C F+ + I L + V++I+R++ V Sbjct: 68 LFVSVLPFKISYYFSGSDW-QFGSELCRFVTAAFYCNMYASILL--MTVISIDRFLAVVY 124 Query: 142 PMSNFRFGENHAIMGVAFT----WVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE- 196 PM + + + +FT W +A+A P L+ + +Q G+ T H+ Sbjct: 125 PMQSLSW---RTLGRASFTCLAIWALAIAGVVPLLLK-----EQTIQVP-GLGITTCHDV 175 Query: 197 --ETNNESFVIY----MFVVHFIIPLIVIFFCYGQLVFTVKEAA 234 ET E + Y V F +PLI+ CY ++ + +A Sbjct: 176 LSETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSA 219 >3OE9-A nrPDB Length = 499 Score = 35.4 bits (80), Expect = 0.035, Method: Compositional matrix adjust. Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 37/194 (19%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL---YTSLHGY 102 ++ + G N L + V KKLR+ + L+L+VADL F TL Sbjct: 57 IIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLL-----FVITLPFWAVDAVAN 111 Query: 103 FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR----FGENHAIMGVA 158 + FG C T+ ++W L ++++RY+ + ++ R E +GV Sbjct: 112 WYFGNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGV- 170 Query: 159 FTWVMALACAAPPLV------GWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMF---V 209 W+ AL P + RYI C D + P N+ V++ F + Sbjct: 171 --WIPALLLTIPDFIFANVSEADDRYI-----C----DRFYP----NDLWVVVFQFQHIM 215 Query: 210 VHFIIPLIVIFFCY 223 V I+P IVI CY Sbjct: 216 VGLILPGIVILSCY 229 Score = 34.7 bits (78), Expect = 0.067, Method: Compositional matrix adjust. Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 15/91 (16%) Query: 247 EKEVTRMVIIMVIAFLICWLP-YAGVAFYIF-----THQGSDFGPIFMTIPAFFAKTSAV 300 +++ + +I+++AF CWLP Y G++ F QG +F T+ + + T A+ Sbjct: 405 KRKALKPTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFEN---TVHKWISITEAL 461 Query: 301 ------YNPVIYIMMNKQFRNCMVTTLCCGK 325 NP++Y + +F+ L G+ Sbjct: 462 AFFHCCLNPILYAFLGAKFKTSAQHALTSGR 492 >6D9H-R nrPDB Length = 389 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 55/296 (18%), Positives = 114/296 (38%), Gaps = 31/296 (10%) Query: 41 AAYM---FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 AAY+ L+ ++ P N L ++ ++ LR +++LAVAD+ G L Sbjct: 65 AAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADV--AVGALVIPLAI 122 Query: 98 SLHGYFVFGPT----GCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENH 152 ++ GP C + + + ++ +L+ +A++RY+ V P+ Sbjct: 123 LIN----IGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 178 Query: 153 AIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHF 212 A + +A W+++ P+ GW+ + P + E + ++V+F Sbjct: 179 AAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 238 Query: 213 --------------IIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMV 258 +I L V + QL K+ +A + E ++ + + +++ Sbjct: 239 NFFVWVLPPLLLMVLIYLEVFYLIRKQL---NKKVSASSGDPQKYYGKELKIAKSLALIL 295 Query: 259 IAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFR 314 F + WLP + I I F ++ NP++Y ++FR Sbjct: 296 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFR 351 >5UEN-A nrPDB Length = 416 Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust. Identities = 31/144 (21%), Positives = 64/144 (44%), Gaps = 14/144 (9%) Query: 41 AAYM---FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 AAY+ L+ ++ P N L ++ ++ LR +++LAVAD + G L Sbjct: 11 AAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVAD--VAVGALVIPLAI 68 Query: 98 SLHGYFVFGPT----GCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENH 152 ++ GP C + + + ++ +L+ +A++RY+ V P+ Sbjct: 69 LIN----IGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 124 Query: 153 AIMGVAFTWVMALACAAPPLVGWS 176 A + +A W+++ P+ GW+ Sbjct: 125 AAVAIAGCWILSFVVGLTPMFGWN 148 >4PHU-A nrPDB Length = 491 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 50 LGFPINFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMV 87 LGFP+N L + H +LR TP LNL +DL + Sbjct: 31 LGFPLNVLAIRGATAHARLRLTPSAVYALNLGCSDLLLT 69 >5ZTY-A nrPDB Length = 500 Score = 31.6 bits (70), Expect = 0.49, Method: Compositional matrix adjust. Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 15/149 (10%) Query: 36 QFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILL-NLAVADLFMVFGGFTTT 94 Q + +A LL +L N LY+ + +LR +Y+ + +LA+AD + Sbjct: 31 QKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLALADFLA-----SVV 85 Query: 95 LYTSLHGYFVFGPTGCNLEGFFATLGGEI------ALWSLVVLAIERYVVVCKPMS-NFR 147 S + VF G + + F G + ++ SL++ AI+RY+ + P S Sbjct: 86 FACSFVNFHVF--HGVDSKAVFLLKIGSVTMTFTASVGSLLLAAIDRYLCLRYPPSYKAL 143 Query: 148 FGENHAIMGVAFTWVMALACAAPPLVGWS 176 A++ + WV++ + PL+GW+ Sbjct: 144 LTRGRALVLLGIMWVLSALVSYLPLMGWT 172 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 14/77 (18%), Positives = 35/77 (45%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ + + E+ + + +++ LICW P + + SD + + Sbjct: 379 DAYARMRLDVELAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLIN 438 Query: 299 AVYNPVIYIMMNKQFRN 315 ++ NPVIY + +++ R+ Sbjct: 439 SMVNPVIYALRSEEIRS 455 >1V9D-A nrPDB Length = 340 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 15/26 (57%) Query: 94 TLYTSLHGYFVFGPTGCNLEGFFATL 119 TLY L YFVF P ++E FF L Sbjct: 273 TLYKELGDYFVFDPKKLSVEEFFMDL 298 >3OBV-E nrPDB Length = 457 Score = 31.2 bits (69), Expect = 0.67, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 15/26 (57%) Query: 94 TLYTSLHGYFVFGPTGCNLEGFFATL 119 TLY L YFVF P ++E FF L Sbjct: 344 TLYKELGDYFVFDPKKLSVEEFFMDL 369 >4WMJ-A nrPDB Length = 556 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%) Query: 95 LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYV---VVCKPMSNFRFGEN 151 L T+ FG N+ GF+ +GG +LWS + L+I Y+ K + F +N Sbjct: 249 LSTNGEKVTAFGIDPKNMFGFWDWVGGRYSLWSAIGLSISLYIGFENFEKLLDGANFMDN 308 Query: 152 H 152 H Sbjct: 309 H 309 >5ZKQ-A nrPDB Length = 438 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 33/154 (21%), Positives = 67/154 (43%), Gaps = 11/154 (7%) Query: 76 LLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEG--FFATLGGEIALWSLVVLAI 133 ++NL +AD+ + +Y G ++ CN+ G FF +A L V+ Sbjct: 58 MVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAF--LGVITY 115 Query: 134 ERYVVVCKPMSNFRFGENHAIMGVAFT---WVMALACAAPPLV-GWSRYIPEGMQCSCGI 189 RY V +P+ + N G++ + WV + A+ L+ + +P+ Sbjct: 116 NRYQAVTRPIKTAQ--ANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGDVT 173 Query: 190 DYYTPHEETNNESFVIYMFVV-HFIIPLIVIFFC 222 + +E+ + +I++F+V F + ++I FC Sbjct: 174 RCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFC 207 >2YEV-A nrPDB Length = 791 Score = 28.1 bits (61), Expect = 6.3, Method: Compositional matrix adjust. Identities = 10/22 (45%), Positives = 13/22 (59%) Query: 171 PLVGWSRYIPEGMQCSCGIDYY 192 P VGW+ Y P Q G+D+Y Sbjct: 135 PSVGWTFYYPFSAQSESGVDFY 156 >5ZKP-A nrPDB Length = 466 Score = 27.7 bits (60), Expect = 7.7, Method: Compositional matrix adjust. Identities = 38/209 (18%), Positives = 88/209 (42%), Gaps = 11/209 (5%) Query: 22 SPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQH---KKLRTPLNYILLN 78 +P ++ +++++ ++ +LG N L+V + KK + ++N Sbjct: 2 APEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKF-NEIKIFMVN 60 Query: 79 LAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVV 138 L +AD+ + +Y G ++ CN+ G + ++ L V+ RY Sbjct: 61 LTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRYQA 120 Query: 139 VCKPMSNFRFGENHAIMGVAFT---WVMALACAAPPLV-GWSRYIPEGMQCSCGIDYYTP 194 V +P+ + N G++ + WV + A+ L+ + +P+ + Sbjct: 121 VTRPIKTAQ--ANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGDVTRCFEH 178 Query: 195 HEETNNESFVIYMFVV-HFIIPLIVIFFC 222 +E+ + +I++F+V F + ++I FC Sbjct: 179 YEKGSVPVLIIHIFIVFSFFLVFLIILFC 207 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5W0P-A nrPDB 428 e-120 5DYS-A nrPDB 405 e-113 6CMO-R nrPDB 369 e-103 5ZBQ-A nrPDB 270 9e-73 4ZUD-A nrPDB 242 1e-64 4LDO-A nrPDB 239 9e-64 3SN6-R nrPDB 239 2e-63 6B73-A nrPDB 235 2e-62 6IBL-A nrPDB 234 5e-62 6DDF-R nrPDB 225 2e-59 4RWA-A nrPDB 224 5e-59 5DHG-A nrPDB 223 7e-59 2R4S-A nrPDB 220 7e-58 6GPS-A nrPDB 219 1e-57 4MQS-A nrPDB 219 2e-57 4GBR-A nrPDB 219 2e-57 2VT4-A nrPDB 218 3e-57 2KS9-A nrPDB 216 2e-56 5C1M-A nrPDB 214 4e-56 6GDG-A nrPDB 210 6e-55 5UIW-A nrPDB 209 2e-54 5UNF-A nrPDB 208 2e-54 6AKX-A nrPDB 207 7e-54 6DO1-A nrPDB 203 1e-52 6MET-B nrPDB 200 7e-52 5VBL-B nrPDB 199 1e-51 6GPX-A nrPDB 199 2e-51 3PWH-A nrPDB 196 9e-51 3AYN-A nrPDB 195 2e-50 6ME9-A nrPDB 192 1e-49 4WW3-A nrPDB 191 3e-49 5ZBH-A nrPDB 189 2e-48 5WB1-A nrPDB 187 6e-48 4DJH-A nrPDB 183 8e-47 6C1Q-B nrPDB 183 9e-47 5LWE-A nrPDB 181 5e-46 4XEE-A nrPDB 180 6e-46 4XNV-A nrPDB 176 1e-44 4DKL-A nrPDB 176 1e-44 4IAR-A nrPDB 176 1e-44 5WS3-A nrPDB 176 1e-44 4XT3-A nrPDB 175 2e-44 4BWB-A nrPDB 175 2e-44 4EJ4-A nrPDB 174 4e-44 3P0G-A nrPDB 174 4e-44 2LNL-A nrPDB 172 2e-43 4BUO-A nrPDB 171 3e-43 5V54-A nrPDB 171 6e-43 6J20-A nrPDB 169 1e-42 5O9H-A nrPDB 167 5e-42 6A94-A nrPDB 166 1e-41 6G79-S nrPDB 166 1e-41 6N4B-R nrPDB 165 2e-41 6DRY-A nrPDB 162 3e-40 5ZKB-A nrPDB 162 3e-40 6HLP-A nrPDB 161 4e-40 6CM4-A nrPDB 161 5e-40 3PBL-A nrPDB 158 3e-39 4U14-A nrPDB 158 3e-39 5T1A-A nrPDB 157 5e-39 3UON-A nrPDB 156 1e-38 5UVI-A nrPDB 155 2e-38 6BQH-A nrPDB 155 3e-38 4U15-A nrPDB 155 3e-38 5CXV-A nrPDB 154 6e-38 5XSZ-A nrPDB 154 6e-38 5XJM-A nrPDB 154 6e-38 5DSG-A nrPDB 150 1e-36 3RZE-A nrPDB 148 3e-36 5GLH-A nrPDB 145 3e-35 4ZJC-A nrPDB 144 6e-35 5WF6-A nrPDB 144 8e-35 5GLI-A nrPDB 142 2e-34 5WIV-A nrPDB 125 2e-29 5U09-A nrPDB 119 3e-27 3V2Y-A nrPDB 119 3e-27 5XRA-A nrPDB 118 5e-27 4Z36-A nrPDB 113 1e-25 4GRV-A nrPDB 110 6e-25 4NTJ-A nrPDB 98 7e-21 Sequences not found previously or not previously below threshold: 5N2S-A nrPDB 154 6e-38 6D9H-R nrPDB 143 9e-35 3OE9-A nrPDB 126 1e-29 5NDD-A nrPDB 123 1e-28 5NJ6-A nrPDB 119 2e-27 3VW7-A nrPDB 115 2e-26 5ZKP-A nrPDB 111 4e-25 5ZKQ-A nrPDB 107 8e-24 5X33-A nrPDB 105 3e-23 5UEN-A nrPDB 104 5e-23 6D26-A nrPDB 104 5e-23 5ZTY-A nrPDB 90 1e-18 5YWY-A nrPDB 85 4e-17 6AK3-B nrPDB 77 1e-14 4PHU-A nrPDB 69 2e-12 6M9T-A nrPDB 63 2e-10 6IIU-A nrPDB 43 2e-04 2LOT-A nrPDB 37 0.014 4K5Y-A nrPDB 29 3.4 4WFO-A nrPDB 28 5.3 6B3J-R nrPDB 28 5.8 >5W0P-A nrPDB Length = 906 Score = 428 bits (1101), Expect = e-120, Method: Composition-based stats. Identities = 321/347 (92%), Positives = 333/347 (95%) Query: 1 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 60 M GTEGPNFYVPFSN TGVVRSPFE PQYYLAEPWQFSMLAAYMFLLI+LGFPINFLTLY Sbjct: 161 MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLY 220 Query: 61 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG 120 VTVQHKKLRTPLNYILLNLAVADLFMV GGFT+TLYTSLHGYFVFGPTGCNL+GFFATLG Sbjct: 221 VTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG 280 Query: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 180 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPL GWSRYIP Sbjct: 281 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIP 340 Query: 181 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 240 EG+QCSCGIDYYT E NNESFVIYMFVVHF IP+I+IFFCYGQLVFTVKEAAAQQQES Sbjct: 341 EGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES 400 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 ATTQKAEKEVTRMVII VIAFLICW+PYA VAFYIFTHQGS FGPIFMTIPAFFAK++A+ Sbjct: 401 ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQGSCFGPIFMTIPAFFAKSAAI 460 Query: 301 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAP 347 YNPVIYIMMNKQFRNCM+TT+CCGKNPLGDDEAS TVSKTETSQVAP Sbjct: 461 YNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAP 507 >5DYS-A nrPDB Length = 349 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 345/348 (99%), Positives = 345/348 (99%) Query: 1 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 60 M GTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY Sbjct: 2 MCGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 61 Query: 61 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG 120 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT LYTSLHGYFVFGPTGCNLEGFFATLG Sbjct: 62 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTILYTSLHGYFVFGPTGCNLEGFFATLG 121 Query: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 180 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP Sbjct: 122 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 181 Query: 181 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 240 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES Sbjct: 182 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 241 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS FGPIFMTIPAFFAKTSAV Sbjct: 242 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSCFGPIFMTIPAFFAKTSAV 301 Query: 301 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA 348 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA Sbjct: 302 YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA 349 >6CMO-R nrPDB Length = 463 Score = 369 bits (948), Expect = e-103, Method: Composition-based stats. Identities = 298/323 (92%), Positives = 310/323 (95%) Query: 1 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY 60 M GTEGPNFYVPFSN TGVVRSPFE PQYYLAEPWQFSMLAAYMFLLI+LGFPINFLTLY Sbjct: 141 MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLY 200 Query: 61 VTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG 120 VTVQHKKLRTPLNYILLNLAVADLFMV GGFT+TLYTSLHGYFVFGPTGCNL+GFFATLG Sbjct: 201 VTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG 260 Query: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP 180 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPL GWSRYIP Sbjct: 261 GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIP 320 Query: 181 EGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES 240 EG+QCSCGIDYYT E NNESFVIYMFVVHF IP+I+IFFCYGQLVFTVKEAAAQQQES Sbjct: 321 EGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES 380 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 ATTQKAEKEVTRMVII VIAFLICW+PYA VAFYIFTHQGS FGPIFMTIPAFFAK++A+ Sbjct: 381 ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQGSCFGPIFMTIPAFFAKSAAI 440 Query: 301 YNPVIYIMMNKQFRNCMVTTLCC 323 YNPVIYIMMNKQFRNCM+TT+CC Sbjct: 441 YNPVIYIMMNKQFRNCMLTTICC 463 >5ZBQ-A nrPDB Length = 525 Score = 270 bits (689), Expect = 9e-73, Method: Composition-based stats. Identities = 83/354 (23%), Positives = 156/354 (44%), Gaps = 18/354 (5%) Query: 5 EGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ 64 E + + FS K + + FE +L F++ A +I+LG N + + ++ Sbjct: 9 ENHSVHSNFSEKNAQLLA-FENDDCHLPLAMIFTLALA-YGAVIILGVSGNLALIIIILK 66 Query: 65 HKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIA 124 K++R N +++NL+ +DL + T +L ++VFG C L F + ++ Sbjct: 67 QKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVS 126 Query: 125 LWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQ 184 +WSLV++A+ER+ ++ P +R HA +G+A WV+A+A + P L+ + E Q Sbjct: 127 IWSLVLIAVERHQLIINP-RGWRPNNRHAYVGIAVIWVLAVASSLPFLI-YQVMTDEPFQ 184 Query: 185 CSC-------GIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQ 237 + + +++ S+ + V+ + PL IF CY ++ +K Sbjct: 185 NVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMM 244 Query: 238 QESATTQKAEKEVTR---MVIIMVIAFLICWLPYAGV-AFYIFTHQ--GSDFGPIFMTIP 291 + + E R M++ +V+AF +CWLP + + HQ + + + Sbjct: 245 DKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLC 304 Query: 292 AFFAKTSAVYNPVIYIMMNKQFRNCMVTTL-CCGKNPLGDDEASTTVSKTETSQ 344 A S NP+ Y +NK F+ + C DD + +S T + Sbjct: 305 HLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDE 358 >4ZUD-A nrPDB Length = 410 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 60/304 (19%), Positives = 126/304 (41%), Gaps = 14/304 (4%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 + P+ + F M+ ++ ++G N L + V + KL+T + LLNLA+ADL Sbjct: 112 DCPKAG-RHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADL 170 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144 + +YT++ + FG C + + +++ L L+I+RY+ + PM Sbjct: 171 CFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMK 230 Query: 145 N-FRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESF 203 + R A + W++A + P ++ + + E + +Y T Sbjct: 231 SRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL 290 Query: 204 VIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLI 263 + ++ F+ P ++I Y + +K+A Q + ++ ++++ +V+ F Sbjct: 291 GLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQ----KNKPRNDDIFKIIMAIVLFFFF 346 Query: 264 CWLPYAGVAFY--------IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 W+P+ F I + +D M I A + NP+ Y + K+F+ Sbjct: 347 SWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKR 406 Query: 316 CMVT 319 + Sbjct: 407 YFLQ 410 >4LDO-A nrPDB Length = 469 Score = 239 bits (611), Expect = 9e-64, Method: Composition-based stats. Identities = 69/308 (22%), Positives = 128/308 (41%), Gaps = 18/308 (5%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 Y E W M M L+++ N L + + ++L+T NY + +LA ADL M Sbjct: 173 DAYAADEVWVVGM-GIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVM 231 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 L + FG C L ++ +L V+A++RY + P Sbjct: 232 GLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQ 291 Query: 147 -RFGENHAIMGVAFTWVMA-LACAAPPLVGWSR-YIPEGMQC---SCGIDYYTPHEETNN 200 +N A + + W+++ L P + W R E + C D++T N Sbjct: 292 SLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFT------N 345 Query: 201 ESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIA 260 +++ I +V F +PL+++ F Y ++ +EA Q Q+ E + + + I++ Sbjct: 346 QAYAIASSIVSFYVPLVIMVFVYSRVF---QEAKRQLQKIDKFALKEHKALKTLGIIMGT 402 Query: 261 FLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTT 320 F +CWLP+ V +++ + + ++ +NP+IY + FR Sbjct: 403 FTLCWLPFFIVNIVHVIQDNLIRKEVYILL-NWIGYVNSGFNPLIYC-RSPDFRIAFQEL 460 Query: 321 LCCGKNPL 328 LC ++ L Sbjct: 461 LCLRRSSL 468 >3SN6-R nrPDB Length = 514 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 67/333 (20%), Positives = 127/333 (38%), Gaps = 40/333 (12%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 Y E W M M L+++ N L + + ++L+T NY + +LA ADL M Sbjct: 173 DAYAADEVWVVGM-GIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVM 231 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 L + FG C L ++ +L V+A++RY + P Sbjct: 232 GLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQ 291 Query: 147 -RFGENHAIMGVAFTWVMA-LACAAPPLVGWSR-YIPEGMQC---SCGIDYYTPHEETNN 200 +N A + + W+++ L P + W R E + C D++T N Sbjct: 292 SLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFT------N 345 Query: 201 ESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQ------------------------ 236 +++ I +V F +PL+++ F Y ++ K + Sbjct: 346 QAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGH 405 Query: 237 -QQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFA 295 + S+ E + + + I++ F +CWLP+ V +++ + + Sbjct: 406 GLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILL-NWIG 464 Query: 296 KTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 ++ +NP+IY + FR LC ++ L Sbjct: 465 YVNSGFNPLIYC-RSPDFRIAFQELLCLRRSSL 496 >6B73-A nrPDB Length = 418 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 56/290 (19%), Positives = 125/290 (43%), Gaps = 8/290 (2%) Query: 34 PWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT 93 P ++ A ++ ++G N L ++V +++ K++T N + NLA+AD + Sbjct: 116 PAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQ 175 Query: 94 TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGEN 151 + L + FG C + ++++L +++++RY+ VC P+ +FR Sbjct: 176 STVY-LMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLK 234 Query: 152 HAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQC-SCGIDYYTPHEETNNESFVIYMFVV 210 I+ + W+++ + +V + E + C + + + I +F+ Sbjct: 235 AKIINIC-IWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIF 293 Query: 211 HFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAG 270 F+IP+++I CY ++ +K S + + +TR+V+++V F++CW P Sbjct: 294 AFVIPVLIIIVCYTLMILRLKS-VRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHI 352 Query: 271 VAFYIFTHQG--SDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMV 318 S T++ NP++Y +++ F+ C Sbjct: 353 FILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFR 402 >6IBL-A nrPDB Length = 416 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 67/313 (21%), Positives = 124/313 (39%), Gaps = 17/313 (5%) Query: 23 PFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVA 82 F A S+L A + LLI+ G N L + ++L+T N + +LA A Sbjct: 101 EFLDANLAEAAAKVMSLLMALVVLLIVAG---NVLVIAAIGSTQRLQTLTNLFITSLACA 157 Query: 83 DLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKP 142 DL + + G +++G C L L ++ +L V+AI+RY+ + P Sbjct: 158 DLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSP 217 Query: 143 MSNF-RFGENHAIMGVAFTWVMALACA-APPLVGWSRYIPEGMQCSCGIDYYTPHEETNN 200 A + + W ++ + P ++ W R E Q + N Sbjct: 218 FRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWR--DEDPQALKCYQDPGCCDFVTN 275 Query: 201 ESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAA------QQQESATTQKAEKEVTRMV 254 ++ I ++ F IPL+++ F Y ++ KE +++ S E + + + Sbjct: 276 RAYAIASSIISFYIPLLIMIFVYLRVYREAKEQIRKIDRASKRKTSRVMAMKEHKALKTL 335 Query: 255 IIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIP-AFFAKTSAVYNPVIYIMMNKQF 313 I++ F +CWLP+ V I D P ++ + + ++ NP+IY + F Sbjct: 336 GIIMGVFTLCWLPFFLVN--IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDF 392 Query: 314 RNCMVTTLCCGKN 326 R L + Sbjct: 393 RKAFKRLLAFPRK 405 >6DDF-R nrPDB Length = 356 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 69/301 (22%), Positives = 134/301 (44%), Gaps = 11/301 (3%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 PQ + A ++ ++G NFL +YV V++ K++T N + NLA+AD Sbjct: 54 LCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA 113 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144 ++ L G + FG C + ++++L ++++RY+ VC P+ Sbjct: 114 LATSTLPFQSVNY-LMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK 172 Query: 145 --NFRFGENHAIMGVAFTWVMALACAAP-PLVGWSRYIPEGMQCSCGIDYYTPHEETNNE 201 +FR N I+ V W+++ A P + ++Y + C+ + T + Sbjct: 173 ALDFRTPRNAKIVNVC-NWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW---EN 228 Query: 202 SFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAF 261 I +F+ FI+P+++I CYG ++ +K S + + +TRMV+++V F Sbjct: 229 LLKICVFIFAFIMPVLIITVCYGLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVF 287 Query: 262 LICWLPYAGVAFY--IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVT 319 ++CW P + T + F + T++ NPV+Y +++ F+ C Sbjct: 288 IVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 347 Query: 320 T 320 Sbjct: 348 F 348 >4RWA-A nrPDB Length = 411 Score = 224 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 62/295 (21%), Positives = 127/295 (43%), Gaps = 13/295 (4%) Query: 40 LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL 99 + A + +G N L ++ V++ K++T N + NLA+AD L Sbjct: 125 ITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATST-LPFQSAKYL 183 Query: 100 HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGV 157 + FG C ++++L +++++RY+ VC P+ +FR ++ + Sbjct: 184 METWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINI 243 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 WV+A P ++ + P C + + +P + + I +F+ F++P++ Sbjct: 244 C-IWVLASGVGVP-IMVMAVTRPRDGAVVCMLQFPSPSWYWDTVT-KICVFLFAFVVPIL 300 Query: 218 VIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFT 277 +I CYG + + S ++ + +TRMV+++V AF++CW P Sbjct: 301 IITVCYGL-MLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL 359 Query: 278 HQGSDFGPI---FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG 329 P+ + + ++ NPV+Y +++ F+ C LC + P G Sbjct: 360 VDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQ-LC--RKPCG 411 >5DHG-A nrPDB Length = 424 Score = 223 bits (569), Expect = 7e-59, Method: Composition-based stats. Identities = 63/291 (21%), Positives = 122/291 (41%), Gaps = 10/291 (3%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 + + + G N L +YV ++H K++T N + NLA+AD ++ Sbjct: 126 VTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT-LPFQGTD 184 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF--RFGENHAIM 155 L G++ FG C + ++L ++++RYV +C P+ R + Sbjct: 185 ILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAV 244 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIP 215 VA W +A P + S + E + C ++ TP + F I +F+ FI+P Sbjct: 245 NVA-IWALASVVGVPVAIMGSAQV-EDEEIECLVEIPTPQDYWGP-VFAICIFLFSFIVP 301 Query: 216 LIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAF-- 273 ++VI CY ++ ++ S + + +TR+V+++V F+ CW P Sbjct: 302 VLVISVCYSLMIRRLR-GVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQ 360 Query: 274 YIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCG 324 + S+ + ++ NP++Y +++ F+ C CC Sbjct: 361 GLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRK-FCCA 410 >2R4S-A nrPDB Length = 342 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 66/328 (20%), Positives = 126/328 (38%), Gaps = 40/328 (12%) Query: 32 AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF 91 E W M M L+++ N L + + ++L+T NY + +LA ADL M Sbjct: 6 DEVWVVGM-GIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVV 64 Query: 92 TTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGE 150 L + FG C L ++ +L V+A++RY + P + Sbjct: 65 PFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTK 124 Query: 151 NHAIMGVAFTWVMA-LACAAPPLVGWSR-YIPEGMQC---SCGIDYYTPHEETNNESFVI 205 N A + + W+++ L P + W R E + C D++T N+++ I Sbjct: 125 NKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFT------NQAYAI 178 Query: 206 YMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQ-------------------------QQES 240 +V F +PL+++ F Y ++ K + + S Sbjct: 179 ASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRS 238 Query: 241 ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAV 300 + E + + + I++ F +CWLP+ V +++ + + ++ Sbjct: 239 SKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILL-NWIGYVNSG 297 Query: 301 YNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 +NP+IY + FR LC ++ L Sbjct: 298 FNPLIYC-RSPDFRIAFQELLCLRRSSL 324 >6GPS-A nrPDB Length = 429 Score = 219 bits (559), Expect = 1e-57, Method: Composition-based stats. Identities = 61/342 (17%), Positives = 123/342 (35%), Gaps = 59/342 (17%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 +L L+ + GF N L + + + +KKL+ + LLNLA++DL + S Sbjct: 43 LLPPLYSLVFIFGFVGNMLVVLILINYKKLKCLTDIYLLNLAISDLLFLITLPLWAH--S 100 Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR-FGENHAIMGV 157 +VFG C L +G ++ +++L I+RY+ + + + ++ Sbjct: 101 AANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTS 160 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 TW++A+ + P ++ +++ E CG + N I ++ ++PL+ Sbjct: 161 VITWLVAVFASVPNII-FTKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLL 215 Query: 218 VIFFCYGQLVFTVKEAA------------------------------------------- 234 ++ CY ++ T+ Sbjct: 216 IMVICYSGILKTLLRMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVG 275 Query: 235 AQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY--------IFTHQGSDFGPI 286 Q E +K R++ ++I + + W PY V + + + Sbjct: 276 KDQFEEVEEEKKRHRDVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQ 335 Query: 287 FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 + T NP+IY + ++FR+ L C PL Sbjct: 336 ATQVTETLGMTHCCINPIIYAFVGEEFRSLFHIALGCRIAPL 377 >4MQS-A nrPDB Length = 351 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 67/308 (21%), Positives = 128/308 (41%), Gaps = 25/308 (8%) Query: 37 FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 ++A + L+ ++G N L + ++ L+T NY L +LA ADL + Sbjct: 43 IVLVAGSLSLVTIIG---NILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTL 99 Query: 97 TSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAIM 155 ++ GY+ GP C+L + ++ +L++++ +RY V KP++ + A M Sbjct: 100 YTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGM 159 Query: 156 GVAFTWVMALACAAPPLVGWS--RYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFI 213 +A WV++ AP ++ W + C I +++ N + + F Sbjct: 160 MIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS------NAAVTFGTAIAAFY 213 Query: 214 IPLIVIFFCYGQLVFTVKEAAAQQQESATTQK------------AEKEVTRMVIIMVIAF 261 +P+I++ Y + K + ++ + EK+VTR ++ +++AF Sbjct: 214 LPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSTRKKPPPSREKKVTRTILAILLAF 273 Query: 262 LICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 +I W PY V I T TI + ++ NP Y + N F+ L Sbjct: 274 IITWAPYN-VMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL 332 Query: 322 CCGKNPLG 329 C +G Sbjct: 333 MCHYKNIG 340 >4GBR-A nrPDB Length = 309 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 68/303 (22%), Positives = 127/303 (41%), Gaps = 18/303 (5%) Query: 32 AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF 91 E W M M L+++ N L + + ++L+T NY + +LA ADL M Sbjct: 1 DEVWVVGM-GIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVV 59 Query: 92 TTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGE 150 L + FG C L ++ +L V+A++RY + P + Sbjct: 60 PFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTK 119 Query: 151 NHAIMGVAFTWVMA-LACAAPPLVGWSR-YIPEGMQC---SCGIDYYTPHEETNNESFVI 205 N A + + W+++ L P + W R E + C D++T N+++ I Sbjct: 120 NKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFT------NQAYAI 173 Query: 206 YMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICW 265 +V F +PL+++ F Y ++ +EA Q Q+ E + + + I++ F +CW Sbjct: 174 ASSIVSFYVPLVIMVFVYSRVF---QEAKRQLQKIDKFCLKEHKALKTLGIIMGTFTLCW 230 Query: 266 LPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGK 325 LP+ V +++ + + ++ +NP+IY + FR LC + Sbjct: 231 LPFFIVNIVHVIQDNLIRKEVYILL-NWIGYVNSGFNPLIYC-RSPDFRIAFQELLCLRR 288 Query: 326 NPL 328 + L Sbjct: 289 SSL 291 >2VT4-A nrPDB Length = 313 Score = 218 bits (556), Expect = 3e-57, Method: Composition-based stats. Identities = 62/303 (20%), Positives = 124/303 (40%), Gaps = 13/303 (4%) Query: 31 LAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG 90 L++ W+ M M L+++L N L + ++L+T N + +LA ADL + Sbjct: 6 LSQQWEAGMSL-LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLV 64 Query: 91 FTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFG 149 + G +++G C L L ++ +L V+AI+RY+ + P Sbjct: 65 VPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMT 124 Query: 150 ENHAIMGVAFTWVMALACA-APPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMF 208 A + + W ++ + P ++ W R E Q + N ++ I Sbjct: 125 RARAKVIICTVWAISALVSFLPIMMHWWR--DEDPQALKCYQDPGCCDFVTNRAYAIASS 182 Query: 209 VVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQK----AEKEVTRMVIIMVIAFLIC 264 ++ F IPL+++ F ++ KE + ++ ++ E + + + I++ F +C Sbjct: 183 IISFYIPLLIMIFVALRVYREAKEQIRKIDRASKRKRVMLMREHKALKTLGIIMGVFTLC 242 Query: 265 WLPYAGVAFYIFTHQGSDFGPIFMTIP-AFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 WLP+ V I D P ++ + + ++ NP+IY + FR L Sbjct: 243 WLPFFLVN--IVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF 299 Query: 324 GKN 326 + Sbjct: 300 PRK 302 >2KS9-A nrPDB Length = 364 Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 74/313 (23%), Positives = 136/313 (43%), Gaps = 9/313 (2%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 P ++ WQ + AA ++++ N + +++ + HK++RT NY L+NLA A+ M Sbjct: 22 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASM 81 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 ++H + +G C FF +++S+ +A +RY+ + P+ Sbjct: 82 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQP- 140 Query: 147 RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 R + + WV+AL A P + + C I++ + + + I Sbjct: 141 RLSATATKVVICVIWVLALLLAFPQGYYSTTETMP-SRVVCMIEWPEHPNKIYEKVYHIC 199 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTV--KEAAAQQQESATTQKAEKE-VTRMVIIMVIAFLI 263 + V+ + +PL+VI + Y + T+ E + Q + K V +M+I++V F I Sbjct: 200 VTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAI 259 Query: 264 CWLPYAGVAFYIFTHQGS---DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTT 320 CWLP+ + + F + A +S +YNP+IY +N +FR Sbjct: 260 CWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHA 319 Query: 321 L-CCGKNPLGDDE 332 CC GD E Sbjct: 320 FRCCPFISAGDYE 332 >5C1M-A nrPDB Length = 296 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 69/298 (23%), Positives = 134/298 (44%), Gaps = 11/298 (3%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 PQ + A ++ ++G NFL +YV V++ K++T N + NLA+AD Sbjct: 5 LCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA 64 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144 ++ L G + FG C + ++++L ++++RY+ VC P+ Sbjct: 65 LATSTLPFQSVNY-LMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK 123 Query: 145 --NFRFGENHAIMGVAFTWVMALACAAP-PLVGWSRYIPEGMQCSCGIDYYTPHEETNNE 201 +FR N I+ V W+++ A P + ++Y + C+ + T + Sbjct: 124 ALDFRTPRNAKIVNVC-NWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW---EN 179 Query: 202 SFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAF 261 I +F+ FI+P+++I CYG ++ +K S + + +TRMV+++V F Sbjct: 180 LLKICVFIFAFIMPVLIITVCYGLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVF 238 Query: 262 LICWLPYAGVAFY--IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCM 317 ++CW P + T + F + T++ NPV+Y +++ F+ C Sbjct: 239 IVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF 296 >6GDG-A nrPDB Length = 479 Score = 210 bits (535), Expect = 6e-55, Method: Composition-based stats. Identities = 62/290 (21%), Positives = 122/290 (42%), Gaps = 17/290 (5%) Query: 47 LIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFG 106 + +L N L + + L+ NY +++LA AD+ G ++ F Sbjct: 179 IAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADI--AVGVLAIPFAITISTGFCAA 236 Query: 107 PTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMAL 165 GC F + + +++SL+ +AI+RY+ + P+ N A +A WV++ Sbjct: 237 CHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSF 296 Query: 166 ACAAPPLVGWSRY--IPEGMQCSCGI---DYYTPHEETNNESFVIY-MFVVHFIIPLIVI 219 A P++GW+ EG S G E+ ++++Y F ++PL+++ Sbjct: 297 AIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLM 356 Query: 220 FFCYGQLVFTVKEAAAQQ-------QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVA 272 Y ++ + Q + + +T + E + + I+V F +CWLP + Sbjct: 357 LGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIIN 416 Query: 273 FYIFTHQGSDFGPIF-MTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 + F P++ M + + T++V NP IY ++FR + Sbjct: 417 CFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKII 466 >5UIW-A nrPDB Length = 411 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 75/391 (19%), Positives = 142/391 (36%), Gaps = 67/391 (17%) Query: 16 KTGVVRSPFEAPQYYLAEPWQ--------FSMLAAYMFLLIMLGFPINFLTLYVTVQHKK 67 V SP YY +EP Q +L L+ + GF N L + + + +K+ Sbjct: 3 PDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKR 62 Query: 68 LRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWS 127 L++ + LLNLA++DLF + Y + + FG T C L +G ++ Sbjct: 63 LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ--WDFGNTMCQLLTGLYFIGFFSGIFF 120 Query: 128 LVVLAIERYVVVCKPMSNFR-FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCS 186 +++L I+RY+ V + + ++ TWV+A+ + P ++ ++R EG+ + Sbjct: 121 IILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNII-FTRSQKEGLHYT 179 Query: 187 CGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAA------------ 234 C + + + + ++ ++PL+V+ CY ++ T+ Sbjct: 180 CSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKKYTCTVCGYIYN 239 Query: 235 -------------------------------AQQQESATTQKAEKEVTRMVIIMVIAFLI 263 Q E +K R++ ++I + + Sbjct: 240 PEDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEEEKKRHRDVRLIFTIMIVYFL 299 Query: 264 CWLPYAGVAFY--------IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 W PY V + S+ M + T NP+IY + ++FRN Sbjct: 300 FWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRN 359 Query: 316 ----CMVTTLCCGKNPLGDDEASTTVSKTET 342 + C + EA S T Sbjct: 360 YLLVFFQKHIFCKCCSIFQQEAPERASSVYT 390 >5UNF-A nrPDB Length = 411 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 61/291 (20%), Positives = 122/291 (41%), Gaps = 13/291 (4%) Query: 40 LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL 99 + +++ ++GF +N + + + K + + + NLAVADL ++ Y S Sbjct: 123 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 182 Query: 100 HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAF 159 ++FGP C + G F TL +++ + ++++RY V P + R A V Sbjct: 183 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 242 Query: 160 TWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFV-IYMFVVHFIIPLIV 218 W MA + P E + + I + P + + + + ++ FIIPLI Sbjct: 243 VWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIF 302 Query: 219 IFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY---- 274 I CY + ++ + + +V +M +V+AF+ICWLP+ + F Sbjct: 303 IATCYFGI----RKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALA 358 Query: 275 ----IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 I + + + + T++ NP +Y + +F+ + + Sbjct: 359 WMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF 409 >6AKX-A nrPDB Length = 381 Score = 207 bits (526), Expect = 7e-54, Method: Composition-based stats. Identities = 71/374 (18%), Positives = 138/374 (36%), Gaps = 63/374 (16%) Query: 16 KTGVVRSPFEAPQYYLAEPWQ--------FSMLAAYMFLLIMLGFPINFLTLYVTVQHKK 67 V SP YY +EP Q +L L+ + GF N L + + + +K+ Sbjct: 3 PDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKR 62 Query: 68 LRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWS 127 L++ + LLNLA++DLF + Y + + FG T C L +G ++ Sbjct: 63 LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ--WDFGNTMCQLLTGLYFIGFFSGIFF 120 Query: 128 LVVLAIERYVVVCKPMSNFR-FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCS 186 +++L I+RY+ V + + ++ TWV+A+ + P ++ ++R EG+ + Sbjct: 121 IILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNII-FTRSQKEGLHYT 179 Query: 187 CGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAA------------ 234 C + + + + ++ ++PL+V+ CY ++ T+ Sbjct: 180 CSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKKYTCTVCGYIYN 239 Query: 235 -------------------------------AQQQESATTQKAEKEVTRMVIIMVIAFLI 263 Q E +K R++ ++I + + Sbjct: 240 PEDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEEEKKRHRDVRLIFTIMIVYFL 299 Query: 264 CWLPYAGVAFY--------IFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 W PY V + S+ M + T NP+IY + ++FRN Sbjct: 300 FWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRN 359 Query: 316 CMVTTLCCGKNPLG 329 ++ G Sbjct: 360 YLLVFFQKHIAKRG 373 >6DO1-A nrPDB Length = 425 Score = 203 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 49/242 (20%), Positives = 101/242 (41%), Gaps = 2/242 (0%) Query: 12 PFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTP 71 S + G+ R + P+ + F M+ ++ ++G N L + V + KL+T Sbjct: 11 NSSTEDGIKRIQDDCPKAG-RHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTV 69 Query: 72 LNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVL 131 + LLNLA+ADL + +YT++ + FG C + + +++ L L Sbjct: 70 ASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCL 129 Query: 132 AIERYVVVCKPMSN-FRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGID 190 +I+RY+ + PM + R A + W++A + P ++ + + E + Sbjct: 130 SIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAF 189 Query: 191 YYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 +Y T + ++ F+ P ++I Y + +K+A + T K + Sbjct: 190 HYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYDLEDNWETLNDNLKVI 249 Query: 251 TR 252 + Sbjct: 250 EK 251 Score = 72.8 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 36/91 (39%), Gaps = 8/91 (8%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY--------IFTHQGSDFGPIFMTI 290 E + ++ ++++ +V+ F W+P+ F I + +D M I Sbjct: 333 EIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPI 392 Query: 291 PAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 A + NP+ Y + K+F+ + L Sbjct: 393 TICIAYFNNCLNPLFYGFLGKKFKRYFLQLL 423 >6MET-B nrPDB Length = 313 Score = 200 bits (509), Expect = 7e-52, Method: Composition-based stats. Identities = 68/320 (21%), Positives = 134/320 (41%), Gaps = 28/320 (8%) Query: 19 VVRSPFEAPQYYLAEPWQ--------FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRT 70 V SP YY +EP Q +L L+ + GF N L + + + K+L++ Sbjct: 4 QVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKS 63 Query: 71 PLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVV 130 + LLNLA++DLF + Y + + FG T C L +G ++ +++ Sbjct: 64 MTDIYLLNLAISDLFFLLTVPFWAHYAAAQ--WDFGNTMCQLLTGLYFIGFFSGIFFIIL 121 Query: 131 LAIERYVVVCKPMSNFR-FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGI 189 L I+RY+ V + + ++ TWV+A+ + P ++ ++R EG+ +C Sbjct: 122 LTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGII-FTRSQKEGLHYTCSS 180 Query: 190 DYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKE 249 + + + + ++ ++PL+V+ CY ++ T+ +K Sbjct: 181 HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLR--------CRNEKKRHR 232 Query: 250 VTRMVIIMVIAFLICWLPYAGVAFY--------IFTHQGSDFGPIFMTIPAFFAKTSAVY 301 R++ ++I + + W PY V + S+ M + T Sbjct: 233 AVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCI 292 Query: 302 NPVIYIMMNKQFRNCMVTTL 321 NP+IY + ++FRN ++ Sbjct: 293 NPIIYAFVGEKFRNYLLVFF 312 >5VBL-B nrPDB Length = 407 Score = 199 bits (507), Expect = 1e-51, Method: Composition-based stats. Identities = 65/344 (18%), Positives = 129/344 (37%), Gaps = 53/344 (15%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQH-KKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 +++ A L+ +LG N L L+ + ++ R + + +LAVADL V Y Sbjct: 47 ALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATY 106 Query: 97 TSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGEN-HAIM 155 T + FG C L + + + + L L+ +RY+ + +P++N R + Sbjct: 107 TYRDYDWPFGTFFCKLSSYLIFVNMYASAFCLTGLSFDRYLAIVRPVANARLRLRVSGAV 166 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEG-MQCSCGIDYYTPHEETNNESFVIYMFV----V 210 A WV+A A P +V + E + C +DY ++ ++ + + V V Sbjct: 167 ATAVLWVLAALLAMPVMVLRTTGDLENTNKVQCYMDYSMVATVSSEWAWEVGLGVSSTTV 226 Query: 211 HFIIPLIVIFFCYGQLVFTVKEAA------------------------------------ 234 F++P ++ CY + T+ Sbjct: 227 GFVVPFTIMLTCYFFIAQTIAMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVC 286 Query: 235 ---AQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI----FTHQGSDFGPIF 287 ++ + + + +++++V+ F +C +PY V H DF Sbjct: 287 PLCGVGKDQFEEVEERRRLLSIIVVLVVTFALCKMPYHLVKTLYMLGSLLHWPCDFDLFL 346 Query: 288 MTI---PAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 M I + ++ NP +Y + +FR + L G++ L Sbjct: 347 MNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLLMGQSRL 390 >6GPX-A nrPDB Length = 349 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 58/335 (17%), Positives = 120/335 (35%), Gaps = 59/335 (17%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 +L L+ + GF N L + + + +KKL+ + LLNLA++DL + S Sbjct: 16 LLPPLYSLVFIFGFVGNMLVVLILINYKKLKCLTDIYLLNLAISDLLFLITLPLWAH--S 73 Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR-FGENHAIMGV 157 +VFG C L +G ++ +++L I+RY+ + + + ++ Sbjct: 74 AANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTS 133 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 TW++A+ + P ++ +++ E CG + N I ++ ++PL+ Sbjct: 134 VITWLVAVFASVPNII-FTKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLL 188 Query: 218 VIFFCYGQLVFTVKEAA------------------------------------------- 234 ++ CY ++ T+ Sbjct: 189 IMVICYSGILKTLLRMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVG 248 Query: 235 AQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY--------IFTHQGSDFGPI 286 Q E +K R++ ++I + + W PY V + + + Sbjct: 249 KDQFEEVEEEKKRHRDVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQ 308 Query: 287 FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 + T NP+IY + ++FR+ L Sbjct: 309 ATQVTETLGMTHCCINPIIYAFVGEKFRSLFHIAL 343 >3PWH-A nrPDB Length = 329 Score = 196 bits (499), Expect = 9e-51, Method: Composition-based stats. Identities = 62/290 (21%), Positives = 121/290 (41%), Gaps = 17/290 (5%) Query: 47 LIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFG 106 + +L N L + + L+ NY +++LA AD+ + G ++ F Sbjct: 16 IAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILV--GVLAIPFAITISTGFCAA 73 Query: 107 PTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMAL 165 GC F + + +++SL+ +AI+RY+ + P+ N A +A WV++ Sbjct: 74 CHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSF 133 Query: 166 ACAAPPLVGWSRY--IPEGMQCSCGI---DYYTPHEETNNESFVIY-MFVVHFIIPLIVI 219 A P++GW+ EG S G E+ ++++Y F ++PL+++ Sbjct: 134 AIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLM 193 Query: 220 FFCYGQLVFTVKEAAAQQ-------QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVA 272 Y ++ + Q + + +T + E + I+ F +CWLP + Sbjct: 194 LGVYLRIFAAARRQLKQMESQPLPGERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIIN 253 Query: 273 FYIFTHQGSDFGPIF-MTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 + F P++ M + A T++V NP IY ++FR + Sbjct: 254 CFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKII 303 >3AYN-A nrPDB Length = 448 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 79/285 (27%), Positives = 142/285 (49%), Gaps = 21/285 (7%) Query: 60 YVTVQHKKLRTPLNYILLNLAVADLFMVFG-GFTTTLYTSLHGYFVFGPTGCNLEGFFAT 118 Y+ + K L+TP N ++NLA +D GF + ++FG C + GF Sbjct: 57 YLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGG 116 Query: 119 LGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSR 177 + G +++ ++ +++I+RY V+ +PM+ + + A + + F W+ ++ A P+ GW Sbjct: 117 IFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGA 176 Query: 178 YIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEA---- 233 Y EG+ C+C DY + ++ S ++ MF++ F P+++IFFCY +V +V Sbjct: 177 YTLEGVLCNCSFDYIS--RDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEM 234 Query: 234 --------AAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGP 285 A + +++ AE + ++ I++V FL+ W PYA VA P Sbjct: 235 AAMAKRLNAKELRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTP 294 Query: 286 IFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL-----CCGK 325 +P FAK SA++NP+IY + + +FR + T CC Sbjct: 295 YAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQF 339 >6ME9-A nrPDB Length = 460 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 61/351 (17%), Positives = 128/351 (36%), Gaps = 59/351 (16%) Query: 29 YYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVF 88 W L+A + + + N L + ++++KLR N L++LA+A+L + F Sbjct: 108 DGARPSWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALANLVVAF 167 Query: 89 GGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR- 147 + L + + FG C F L ++W++ +AI+RY+ +C M+ R Sbjct: 168 YPYPLILVAIFYDGWAFGEEHCKASAFVMGLSVIGSVWNITAIAIDRYLYICHSMAYHRI 227 Query: 148 FGENHAIMGVAFTWVMALACAAPPLV-GWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 + H + + W++ + P G Y P C+ +T + + Sbjct: 228 YRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCT--------FIQTASTQYTAA 279 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQ----------------------------- 237 + V+HF++P+ V+ FCY ++ V +A ++ Sbjct: 280 VVVIHFLLPIAVVSFCYLRIWVLVLQARMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKD 339 Query: 238 -----------------QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQ- 279 +E + ++ + ++ + F IC+ P + + + Sbjct: 340 IPDDWVCPLCGVGKDQFEEVECLKPSDLRSFLTMFVVFVIFAICFAPLNCIGLAVAINPQ 399 Query: 280 --GSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 A ++ NP++Y ++++ FR L NP Sbjct: 400 EMAPQIPEGLFVTSYLLAYFNSCLNPIVYGLLDQNFRREYKRILLALWNPR 450 >4WW3-A nrPDB Length = 350 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 79/285 (27%), Positives = 142/285 (49%), Gaps = 21/285 (7%) Query: 60 YVTVQHKKLRTPLNYILLNLAVADLFMVFG-GFTTTLYTSLHGYFVFGPTGCNLEGFFAT 118 Y+ + K L+TP N ++NLA +D GF + ++FG C + GF Sbjct: 49 YLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGG 108 Query: 119 LGGEIALWSLVVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSR 177 + G +++ ++ +++I+RY V+ +PM+ + + A + + F W+ ++ A P+ GW Sbjct: 109 IFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGA 168 Query: 178 YIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEA---- 233 Y EG+ C+C DY + ++ S ++ MF++ F P+++IFFCY +V +V Sbjct: 169 YTLEGVLCNCSFDYIS--RDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEM 226 Query: 234 --------AAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGP 285 A + +++ AE + ++ I++V FL+ W PYA VA P Sbjct: 227 AAMAKRLNAKELRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTP 286 Query: 286 IFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL-----CCGK 325 +P FAK SA++NP+IY + + +FR + T CC Sbjct: 287 YAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQF 331 >5ZBH-A nrPDB Length = 527 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 58/236 (24%), Positives = 112/236 (47%), Gaps = 11/236 (4%) Query: 5 EGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ 64 E + + FS K + + FE +L F++ A +I+LG N + + ++ Sbjct: 19 ENHSVHSNFSEKNAQLLA-FENDDCHLPLAMIFTLALA-YGAVIILGVSGNLALIIIILK 76 Query: 65 HKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIA 124 K++R N +++NL+ +DL + T +L ++VFG C L F + ++ Sbjct: 77 QKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVS 136 Query: 125 LWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQ 184 +WSLV++A+ER+ ++ P +R HA +G+A WV+A+A + P L+ + E Q Sbjct: 137 IWSLVLIAVERHQLIINP-RGWRPNNRHAYVGIAVIWVLAVASSLPFLI-YQVMTDEPFQ 194 Query: 185 CSC-------GIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEA 233 + + +++ S+ + V+ + PL IF CY ++ +K Sbjct: 195 NVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRR 250 Score = 90.9 bits (224), Expect = 7e-19, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 49/124 (39%), Gaps = 4/124 (3%) Query: 225 QLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGV-AFYIFTHQ--GS 281 +++ T + ++ K + M++ +V+AF +CWLP + + HQ + Sbjct: 397 RVITTFRTGTWDAYDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIAT 456 Query: 282 DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL-CCGKNPLGDDEASTTVSKT 340 + + A S NP+ Y +NK F+ + C DD + +S Sbjct: 457 CNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTM 516 Query: 341 ETSQ 344 T + Sbjct: 517 HTDE 520 >5WB1-A nrPDB Length = 458 Score = 187 bits (475), Expect = 6e-48, Method: Composition-based stats. Identities = 58/289 (20%), Positives = 111/289 (38%), Gaps = 29/289 (10%) Query: 43 YMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGY 102 ++ + G NFL ++ ++++ + +NLA ADL V Y H Sbjct: 47 LYGVVFLFGSIGNFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNS 106 Query: 103 FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWV 162 P C L + +L + +A++RY + A + F W+ Sbjct: 107 LASVP--CTLLTACFYVAMFASLCFITEIALDRYYAIVYMRY---RPVKQACLFSIFWWI 161 Query: 163 MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFC 222 A+ A P + ++ + QC DY E + + + + F+IPL VI +C Sbjct: 162 FAVIIAIPHFMVVTK---KDNQCMTDYDYL---EVSYPIILNVELMLGAFVIPLSVISYC 215 Query: 223 YGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI------F 276 Y ++ V + + + + + R++I +V+ F+I WLPY F + Sbjct: 216 YYRISRIV---------AVSQSRHKGRIVRVLIAVVLVFIIFWLPYHLTLFVDTLKLLKW 266 Query: 277 THQGSDFGPI---FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLC 322 +F + + A NP++Y+ + +FR + L Sbjct: 267 ISSSCEFERSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQELHCLLA 315 >4DJH-A nrPDB Length = 480 Score = 183 bits (465), Expect = 8e-47, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 93/215 (43%), Gaps = 5/215 (2%) Query: 34 PWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT 93 P ++ A ++ ++G N L ++V +++ K++T N + NLA+AD + Sbjct: 19 PAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQ 78 Query: 94 TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGEN 151 + L + FG C + ++++L +++++RY+ VC P+ +FR Sbjct: 79 STVY-LMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLK 137 Query: 152 HAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQC-SCGIDYYTPHEETNNESFVIYMFVV 210 I+ + W+++ + +V + E + C + + + I +F+ Sbjct: 138 AKIINIC-IWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIF 196 Query: 211 HFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQK 245 F+IP+++I CY ++ +K + Sbjct: 197 AFVIPVLIIIVCYTLMILRLKSVRLLSGNIFEMLR 231 Score = 59.3 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 32/81 (39%), Gaps = 2/81 (2%) Query: 240 SATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS--DFGPIFMTIPAFFAKT 297 + + +TR+V+++V F++CW P S T Sbjct: 384 YREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYT 443 Query: 298 SAVYNPVIYIMMNKQFRNCMV 318 ++ NP++Y +++ F+ C Sbjct: 444 NSSLNPILYAFLDENFKRCFR 464 >6C1Q-B nrPDB Length = 422 Score = 183 bits (465), Expect = 9e-47, Method: Composition-based stats. Identities = 68/306 (22%), Positives = 126/306 (41%), Gaps = 24/306 (7%) Query: 26 APQYYLAEPWQFSMLAAYMF--LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD 83 Q YL+ + + A + ++ ++G N L ++VT K RT LNLAVAD Sbjct: 110 YIQKYLSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAK-RTINAIWFLNLAVAD 168 Query: 84 LFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM 143 H ++ FG C++ L ++ L ++ +R+++V KP+ Sbjct: 169 FLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPI 228 Query: 144 SNFRFG-ENHAIMGVAFTWVMALACAAPPLV---GWSRYIPEGMQCSCGIDYYTPHEETN 199 F A + A W +AL P + Y P + CG+DY H++ Sbjct: 229 WCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPP--KVLCGVDY--SHDKRR 284 Query: 200 NESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVI 259 + I V+ F+ PL+ + CY ++ A + + ++V+ +V Sbjct: 285 ERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRST---------KTLKVVVAVVA 335 Query: 260 AFLICWLPYAGVAFYIFTHQGSDFGPIFM----TIPAFFAKTSAVYNPVIYIMMNKQFRN 315 +F I WLPY + + S + + ++ FA + NP+IY++ + F+ Sbjct: 336 SFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQG 395 Query: 316 CMVTTL 321 + +L Sbjct: 396 RLRKSL 401 >5LWE-A nrPDB Length = 331 Score = 181 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 55/295 (18%), Positives = 116/295 (39%), Gaps = 24/295 (8%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 L +L+ ++G N L + V + +T + LLNLA+ADL + + + Sbjct: 28 FLPPLYWLVFIVGALGNSLVILVYWYCARAKTATDMFLLNLAIADLLFLVTLPFWAI--A 85 Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENH---AIM 155 + F C + + + ++ + ++RY+ + + M + E + M Sbjct: 86 AADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCICVDRYIAIAQAMRAHTWREKRLLYSKM 145 Query: 156 GVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIP 215 WV+A A P ++ +S+ E C + Y + + + ++ F +P Sbjct: 146 VCFTIWVLAAALCIPEIL-YSQIKEESGIAICTMVYPSDESTKLKSAVLALKVILGFFLP 204 Query: 216 LIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAF-- 273 +V+ CY ++ T+ +A + + + I ++ F++ PY + Sbjct: 205 FVVMACCYTIIIHTLIQAKKSSK---------HKALKATITVLTVFVLSQFPYNCILLVQ 255 Query: 274 -------YIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 +I S I + A + NPV+Y+ + ++FR +V TL Sbjct: 256 TIDAYAMFISNCAVSTAIDICFQVTQAIAFFHSCLNPVLYVFVGERFRRDLVKTL 310 >4XEE-A nrPDB Length = 541 Score = 180 bits (457), Expect = 6e-46, Method: Composition-based stats. Identities = 74/328 (22%), Positives = 126/328 (38%), Gaps = 48/328 (14%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLN---YILLNLAVADLFMVFGGFTTT 94 ++ A L ++G N +TL+ + K L++ + Y L +LA++DL ++ Sbjct: 33 VLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVE 92 Query: 95 LYTSL--HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGEN 151 LY + H + FG GC F ++ L++ERY+ +C P + Sbjct: 93 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 152 Query: 152 HAIMGVAFTWVMALACAAPPLVGW-------SRYIPEGMQCSCGIDYYTPHEETNNESFV 204 ++ W+ + A P L P G+ C+ +D T +F+ Sbjct: 153 RTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFM 212 Query: 205 IYMFVVHFIIPLIVIFFCYGQL----VFTVKEAAAQQQ--ESATTQKAEKEVTRMVI--- 255 F+ P++VI + V +AA Q + T E M I Sbjct: 213 ------SFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPG 266 Query: 256 -------------IMVIAFLICWLPYAGVAF---YIFTHQGS----DFGPIFMTIPAFFA 295 +VIAF++CWLPY YI Q + DF F + Sbjct: 267 RVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALF 326 Query: 296 KTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 S+ NP++Y +++ FR ++TL C Sbjct: 327 YASSAINPILYNLVSANFRQVFLSTLAC 354 >4XNV-A nrPDB Length = 421 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 64/359 (17%), Positives = 123/359 (34%), Gaps = 59/359 (16%) Query: 17 TGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYIL 76 T V S F+ +QF L A L+ ++GF N + +++ V H K + ++ + Sbjct: 32 TAAVSSSFKC--ALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYM 89 Query: 77 LNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERY 136 NLA+AD V Y ++FG C L+ F + ++ L ++ RY Sbjct: 90 FNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRY 149 Query: 137 VVVCKPMSNF-RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPH 195 V P+ + R + +AI W++ + A P++ +S + D + Sbjct: 150 SGVVYPLKSLGRLKKKNAICISVLVWLI-VVVAISPILFYSGTGVRKNKTITCYDTTSDE 208 Query: 196 EETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVK------------------------ 231 + + + V F +PL++I CYG +V + Sbjct: 209 YLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKMKKYTCTVCGYIYNPEDGDPDN 268 Query: 232 --------------------EAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGV 271 Q E K + +VII++ F + ++P+ + Sbjct: 269 GVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEEPLRRKSIY-LVIIVLTVFAVSYIPFHVM 327 Query: 272 AFYIF----------THQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTT 320 +D + A ++ NP++Y + FR + Sbjct: 328 KTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVNPILYFLAGDTFRRRLSRA 386 >4DKL-A nrPDB Length = 464 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 8/231 (3%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 PQ + A ++ ++G NFL +YV V++ K++T N + NLA+AD Sbjct: 5 LCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA 64 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144 ++ L G + FG C + ++++L ++++RY+ VC P+ Sbjct: 65 LATSTLPFQSVNY-LMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK 123 Query: 145 --NFRFGENHAIMGVAFTWVMALACAAP-PLVGWSRYIPEGMQCSCGIDYYTPHEETNNE 201 +FR N I+ V W+++ A P + ++Y + C+ + T + Sbjct: 124 ALDFRTPRNAKIVNVC-NWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW---EN 179 Query: 202 SFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 I +F+ FI+P+++I CYG ++ +K + + ++ + Sbjct: 180 LLKICVFIFAFIMPVLIITVCYGLMILRLKSVRNIFEMLRIDEGLRLKIYK 230 Score = 68.6 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 40/91 (43%), Gaps = 3/91 (3%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY--IFTHQGSDFGPIFMTIPAFFAK 296 ++ + + +TRMV+++V F++CW P + T + F + Sbjct: 370 DAYEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGY 429 Query: 297 TSAVYNPVIYIMMNKQFRNCMVTTLCCGKNP 327 T++ NPV+Y +++ F+ C C + Sbjct: 430 TNSCLNPVLYAFLDENFKRCFRE-FCIPTSS 459 >4IAR-A nrPDB Length = 401 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 45/234 (19%), Positives = 97/234 (41%), Gaps = 10/234 (4%) Query: 18 GVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILL 77 G + Q ++ PW+ ++ + L+ + N + + +KL TP NY++ Sbjct: 2 GTCSAKDYIYQDSISLPWKVLLVM-LLALITLATTLSNAFVIATVYRTRKLHTPANYLIA 60 Query: 78 NLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYV 137 +LAV DL + + ++ G + G C+ ++W L V+A++RY Sbjct: 61 SLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYW 120 Query: 138 VVCKPMSNF-RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE 196 + + + A + +A WV +++ + PP W + E C ++ Sbjct: 121 AITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFF-WRQAKAEEEVSECVVN------ 173 Query: 197 ETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 T++ + +Y V F P +++ YG++ + A +++ T +V Sbjct: 174 -TDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWETLNDNLKV 226 Score = 77.4 bits (189), Expect = 8e-15, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 37/77 (48%), Gaps = 1/77 (1%) Query: 246 AEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH-QGSDFGPIFMTIPAFFAKTSAVYNPV 304 E++ T+ + I++ AF++CWLP+ ++ + F + +++ NP+ Sbjct: 319 RERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPI 378 Query: 305 IYIMMNKQFRNCMVTTL 321 IY M N+ F+ + Sbjct: 379 IYTMSNEDFKQAFHKLI 395 >5WS3-A nrPDB Length = 560 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 42/226 (18%), Positives = 94/226 (41%), Gaps = 9/226 (3%) Query: 12 PFSNKTGVVRSPFEA---PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKL 68 PF N T F +Y + +++ ++A ++ ++ N L ++ + Sbjct: 34 PFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG-YIIVFVVALIGNVLVCVAVWKNHHM 92 Query: 69 RTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSL 128 RT NY ++NL++AD+ + TL + + FG + C + + T+ +++ +L Sbjct: 93 RTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTL 152 Query: 129 VVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGW--SRYIPEGMQCS 186 +A++R+ +C P+ F+ A + W+++ P + S P + Sbjct: 153 SCIALDRWYAICHPLM-FKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKT 211 Query: 187 CGIDYYTPHE--ETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTV 230 E + + I F+V ++ PL ++ Y Q+ + Sbjct: 212 TLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKL 257 Score = 65.1 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 40/98 (40%), Gaps = 6/98 (6%) Query: 232 EAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH------QGSDFGP 285 + + +A ++ RM++++++ F IC+LP + + + + Sbjct: 448 NCKKRAMSFSKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVY 507 Query: 286 IFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 + T + ++ NP+IY ++ +FR C Sbjct: 508 AWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 545 >4XT3-A nrPDB Length = 362 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 59/295 (20%), Positives = 113/295 (38%), Gaps = 29/295 (9%) Query: 43 YMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGY 102 ++ + G NFL ++ ++++ + +NLA ADL V Y H Sbjct: 47 LYGVVFLFGSIGNFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNS 106 Query: 103 FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWV 162 P C L + +L + +A++RY + A + F W+ Sbjct: 107 LASVP--CTLLTACFYVAMFASLCFITEIALDRYYAIVYMRY---RPVKQACLFSIFWWI 161 Query: 163 MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFC 222 A+ A P + ++ + QC DY E + + + + F+IPL VI +C Sbjct: 162 FAVIIAIPHFMVVTK---KDNQCMTDYDYL---EVSYPIILNVELMLGAFVIPLSVISYC 215 Query: 223 YGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI------F 276 Y ++ V + + + + + R++I +V+ F+I WLPY F + Sbjct: 216 YYRISRIV---------AVSQSRHKGRIVRVLIAVVLVFIIFWLPYHLTLFVDTLKLLKW 266 Query: 277 THQGSDFGPI---FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 +F + + A NP++Y+ + +FR + L + L Sbjct: 267 ISSSCEFERSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQELHCLLAEFRQRL 321 >4BWB-A nrPDB Length = 338 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 71/308 (23%), Positives = 128/308 (41%), Gaps = 24/308 (7%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTP---LNYILLNLAVADLFMVFGGFTTT 94 ++ A L ++G N +TL+ + K L++ ++Y L +LA++DL ++ Sbjct: 20 VLVTAIYLALFVVGTVGNGVTLFTLARKKSLQSLQSRVDYYLGSLALSDLLILLFALPVD 79 Query: 95 LYTSL--HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGEN 151 LY + H + FG GC F ++V L++E Y+ +C P + Sbjct: 80 LYNFIWVHHPWAFGDAGCKGYYFLREACTYATALNVVSLSVELYLAICHPFKAKTLMSRS 139 Query: 152 HAIMGVAFTWVMALACAAPPLV-------GWSRYIPEGMQCSCGIDYYTPHEETNNESFV 204 ++ W+ + A P L P G+ C+ +D T +F+ Sbjct: 140 RTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIVDTATLRVVIQLNTFM 199 Query: 205 IYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQ--ESATTQKAEKEVTRMVIIMVIAFL 262 F+ ++ I+ +L V +AA Q + +A + ++ +VIAF+ Sbjct: 200 --SFLFPMLVASILNTVAARRLTVMVHQAAEQGRVCTEPGRVQALRRGVLVLRAVVIAFV 257 Query: 263 ICWLPYAGVA---FYIFTHQGS----DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 +CWLPY YI Q + DF F + SA NP++Y +++ FR Sbjct: 258 VCWLPYHVRRLMFVYISDEQWTTALFDFYHYFYMLSNALVYVSAAINPILYNLVSANFRQ 317 Query: 316 CMVTTLCC 323 ++TL C Sbjct: 318 VFLSTLAC 325 >4EJ4-A nrPDB Length = 461 Score = 174 bits (442), Expect = 4e-44, Method: Composition-based stats. Identities = 41/215 (19%), Positives = 92/215 (42%), Gaps = 6/215 (2%) Query: 40 LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL 99 + A + +G N L ++ V++ KL+T N + NLA+AD L Sbjct: 17 ITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATST-LPFQSAKYL 75 Query: 100 HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS--NFRFGENHAIMGV 157 + FG C ++++L +++++RY+ VC P+ +FR ++ + Sbjct: 76 METWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINI 135 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 WV+A P ++ + P C + + +P + + I +F+ F++P++ Sbjct: 136 C-IWVLASGVGVP-IMVMAVTQPRDGAVVCMLQFPSPSWYWDTVT-KICVFLFAFVVPIL 192 Query: 218 VIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 +I CYG ++ ++ + + ++ + Sbjct: 193 IITVCYGLMLLRLRSVRNIFEMLRIDEGLRLKIYK 227 Score = 64.3 bits (155), Expect = 8e-11, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPI---FMTIPAFFA 295 ++ ++ + +TRMV+++V AF++CW P + P+ + + Sbjct: 367 DAYEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALG 426 Query: 296 KTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDE 332 ++ NPV+Y +++ F+ C LC + P G E Sbjct: 427 YANSSLNPVLYAFLDENFKRCFRQ-LC--RTPCGRQE 460 >3P0G-A nrPDB Length = 501 Score = 174 bits (442), Expect = 4e-44, Method: Composition-based stats. Identities = 50/248 (20%), Positives = 94/248 (37%), Gaps = 13/248 (5%) Query: 11 VPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRT 70 F +P E W M M L+++ N L + + ++L+T Sbjct: 16 SAFLLAPNRSHAPDHDVTQQRDEVWVVGM-GIVMSLIVLAIVFGNVLVITAIAKFERLQT 74 Query: 71 PLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVV 130 NY + +LA ADL M L + FG C L ++ +L V Sbjct: 75 VTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCV 134 Query: 131 LAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVMA-LACAAPPLVGWSR-YIPEGMQC-- 185 +A++RY + P +N A + + W+++ L P + W R E + C Sbjct: 135 IAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYA 194 Query: 186 -SCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQ 244 D++T N+++ I +V F +PL+++ F Y ++ K + + Sbjct: 195 EETCCDFFT------NQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNIFEMLRIDE 248 Query: 245 KAEKEVTR 252 ++ + Sbjct: 249 GLRLKIYK 256 Score = 79.7 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 38/90 (42%), Gaps = 2/90 (2%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ E + + + I++ F +CWLP+ V +++ + + + Sbjct: 396 DAYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILL-NWIGYVN 454 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 + +NP+IY + FR LC ++ L Sbjct: 455 SGFNPLIYC-RSPDFRIAFQELLCLRRSSL 483 >2LNL-A nrPDB Length = 309 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 106/311 (34%), Gaps = 21/311 (6%) Query: 23 PFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVA 82 +P E ++ L+ +L N L + V + + R+ + LLNLA+A Sbjct: 6 EDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALA 65 Query: 83 DLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKP 142 DL S ++FG C + + + L ++++RY+ + Sbjct: 66 DLLFALTLPIWA--ASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHA 123 Query: 143 MSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNES 202 + W +++ + P + Y P C + Sbjct: 124 TRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVC-YEVLGNDTAKWRMV 182 Query: 203 FVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFL 262 I FI+PL V+ FCYG + T+ +A Q+ R++ +V+ FL Sbjct: 183 LRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQK---------HRAMRVIFAVVLIFL 233 Query: 263 ICWLPYAGVAFYIFTHQGSDFGPI---------FMTIPAFFAKTSAVYNPVIYIMMNKQF 313 +CWLPY V + + + NP+IY + + F Sbjct: 234 LCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNF 293 Query: 314 RNCMVTTLCCG 324 R+ + L Sbjct: 294 RHGFLKILAMH 304 >4BUO-A nrPDB Length = 335 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 70/306 (22%), Positives = 126/306 (41%), Gaps = 22/306 (7%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRT---PLNYILLNLAVADLFMVFGGFTTT 94 ++ A L ++G N +TL+ + K L++ ++Y L +LA++DL ++ Sbjct: 19 VLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSLQSTVDYYLGSLALSDLLILLLAMPVE 78 Query: 95 LYTSL--HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGEN 151 LY + H + FG GC F ++V L++E Y+ +C P + Sbjct: 79 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRS 138 Query: 152 HAIMGVAFTWVMALACAAPPLV-------GWSRYIPEGMQCSCGIDYYTPHEETNNESFV 204 ++ W+ + A P L P G+ C+ +D T +F+ Sbjct: 139 RTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFM 198 Query: 205 IYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLIC 264 F+ ++ I+ +L V +AA +A + ++ +VIAF++C Sbjct: 199 --SFLFPMLVASILNTVIANKLTVMVHQAAFNMTIEPGRVQALRRGVLVLRAVVIAFVVC 256 Query: 265 WLPYAGVAF---YIFTHQGS----DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCM 317 WLPY YI Q + DF F + SA NP++Y +++ FR Sbjct: 257 WLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFRQVF 316 Query: 318 VTTLCC 323 ++TL C Sbjct: 317 LSTLAC 322 >5V54-A nrPDB Length = 395 Score = 171 bits (432), Expect = 6e-43, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 91/215 (42%), Gaps = 10/215 (4%) Query: 28 QYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMV 87 Q ++ PW+ ++ + L+ + N + + +KL TP NY++ +LAV DL + Sbjct: 5 QDSISLPWKVLLVM-LLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVS 63 Query: 88 FGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF- 146 + ++ G + G C+ ++W L V+A++RY + + Sbjct: 64 ILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSA 123 Query: 147 RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 + A + +A WV +++ + PP W + E C ++ T++ + +Y Sbjct: 124 KRTPKRAAVMIALVWVFSISISLPPFF-WRQAKAEEEVSECVVN-------TDHILYTVY 175 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESA 241 V F P +++ YG++ + A ++ Sbjct: 176 STVGAFYFPTLLLIALYGRIYVEARSRIADLEDRW 210 Score = 76.3 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 37/77 (48%), Gaps = 1/77 (1%) Query: 246 AEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH-QGSDFGPIFMTIPAFFAKTSAVYNPV 304 E++ T+ + I++ AF++CWLP+ ++ + F + +++ NP+ Sbjct: 313 RERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPI 372 Query: 305 IYIMMNKQFRNCMVTTL 321 IY M N+ F+ + Sbjct: 373 IYTMSNEDFKQAFHKLI 389 >6J20-A nrPDB Length = 441 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 91/204 (44%), Gaps = 2/204 (0%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 P ++ WQ + AA ++++ N + +++ + HK++RT NY L+NLA A+ M Sbjct: 21 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFANASM 80 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 ++H + +G C FF ++WS+ +A +RY+ + P+ Sbjct: 81 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIWSMTAVAFDRYMAIIHPLQP- 139 Query: 147 RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 R + + WV+AL A P + + C I++ + + + I Sbjct: 140 RLSATATKVVICVIWVLALLLAFPQGYYSTTETMP-SRVVCMIEWPEHPNKIYEKVYHIC 198 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTV 230 + V+ + +PL+VI + Y + + Sbjct: 199 VTVLIYFLPLLVIGYAYTVVGIRL 222 Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Query: 242 TTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS---DFGPIFMTIPAFFAKTS 298 A+++V +M+I++V F ICWLP+ + + F + A +S Sbjct: 344 EQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSS 403 Query: 299 AVYNPVIYIMMNKQFRNCMVTTL-CCGKNPLGDDE 332 +YNP+IY +N +FR CC GD E Sbjct: 404 TMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYE 438 >5O9H-A nrPDB Length = 317 Score = 167 bits (424), Expect = 5e-42, Method: Composition-based stats. Identities = 64/291 (21%), Positives = 119/291 (40%), Gaps = 22/291 (7%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 + ++ ++G N L ++VT K RT LNLAVAD Sbjct: 10 LALVIFAVVFLVGVLGNALVVWVTAFEAK-RTINAIWFLNLAVADFLACLALPALFTSIV 68 Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGV 157 H ++ FG C++ L ++ L ++ +R+++V KP RF A + Sbjct: 69 QHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPAWCQRFRGAGLAWILC 128 Query: 158 AFTWVMALACAAPPLV---GWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFII 214 A W +AL P + Y P + CG+DY H++ + I V+ F+ Sbjct: 129 AVAWGLALLLTIPSALYRVVREEYFPP--KVLCGVDY--SHDKRRERAVAIVRLVLGFLW 184 Query: 215 PLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY 274 PL+ + CY ++ + + + + ++V+ +V +F I WLPY Sbjct: 185 PLLTLTICYTFIL---------LRTWSARETRSTKTLKVVVAVVASFFIFWLPYQVTGIM 235 Query: 275 IFTHQGSDFGPIFM----TIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 + + S + + ++ FA + NP+IY++ + F+ +L Sbjct: 236 MSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRERKSL 286 >6A94-A nrPDB Length = 376 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 52/224 (23%), Positives = 103/224 (45%), Gaps = 15/224 (6%) Query: 30 YLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG 89 +L E ++L A + +L + G N L + KKL+ NY L++LA+AD+ + F Sbjct: 4 HLQEKNWSALLTAVVIILTIAG---NILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFL 60 Query: 90 GFTTTLYTSLHGY-FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF 148 ++ T L+GY + C + + L +W L ++++RYV + P+ + RF Sbjct: 61 VMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRF 120 Query: 149 G-ENHAIMGVAFTWVMALACAAP-PLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 A + + W +++ + P P+ G + SC + +++FV+ Sbjct: 121 NSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLL---------ADDNFVLI 171 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 V F IPL ++ Y + ++++ AA +++ T +V Sbjct: 172 GSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKV 215 Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 36/92 (39%), Gaps = 3/92 (3%) Query: 238 QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH---QGSDFGPIFMTIPAFF 294 Q+ + E++ +++ I+ F++ W P+ D + + + Sbjct: 282 QKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWI 341 Query: 295 AKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 326 S+ NP++Y + NK +R+ + C Sbjct: 342 GYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK 373 >6G79-S nrPDB Length = 364 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 43/233 (18%), Positives = 97/233 (41%), Gaps = 10/233 (4%) Query: 20 VRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNL 79 + + Q ++ PW+ ++ + L+ + N + + +KL TP NY++ +L Sbjct: 1 MSAKDYIYQDSISLPWKVLLVM-LLALITLATTLSNAFVIATVYRTRKLHTPANYLIASL 59 Query: 80 AVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVV 139 AV DL + + ++ G + G C+ ++W L V+A++RY + Sbjct: 60 AVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAI 119 Query: 140 CKPMSNF-RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEET 198 + + A + +A WV +++ + PP W + E C ++ T Sbjct: 120 TDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFF-WRQAKAEEEVSECVVN-------T 171 Query: 199 NNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVT 251 ++ + +Y V F P +++ YG++ + +Q + T ++ + Sbjct: 172 DHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQL 224 Score = 76.3 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Query: 228 FTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH-QGSDFGPI 286 V+ + A ++ E++ T+ + I++ AF++CWLP+ ++ + F Sbjct: 258 VKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLA 317 Query: 287 FMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 + +++ NP+IY M N+ F+ + Sbjct: 318 IFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 352 >6N4B-R nrPDB Length = 495 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 72/364 (19%), Positives = 137/364 (37%), Gaps = 48/364 (13%) Query: 4 TEGPNFYVPF--SNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFL-LIMLGFPINFLTLY 60 +E F F + + F + ++ + A + L L N L L Sbjct: 95 SENLYFQGSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLC 154 Query: 61 VTVQHKKLRT-PLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFF--- 116 V + + LR P + + +LAVADL G +Y+ + + N+ F Sbjct: 155 VILHSRSLRCRPSYHFIGSLAVADLL----GSVIFVYSFIDFHVFHRKDSRNVFLFKLGG 210 Query: 117 ATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLVGW 175 T ++ SL + AI+RY+ + +P++ R A++ W +A+ A PL+GW Sbjct: 211 VTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGW 270 Query: 176 SRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVF------- 228 + E +Q C + +E+++++ V ++ L+ I + Y +++ Sbjct: 271 N---CEKLQSVCSDIFPH-----IDETYLMFWIGVTSVL-LLFIVYAYMYILWKAHSHAV 321 Query: 229 ------TVKEAAAQQQESATTQKAEKEVTRMVIIMV-------IAFLICWLPYAGVAFYI 275 T K E Q + RM I + + +ICW P + Y Sbjct: 322 RMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYD 381 Query: 276 FTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL--CCG-----KNPL 328 + + + ++ NP+IY + +K R+ + C G N + Sbjct: 382 VFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSM 441 Query: 329 GDDE 332 GD + Sbjct: 442 GDSD 445 >6DRY-A nrPDB Length = 411 Score = 162 bits (409), Expect = 3e-40, Method: Composition-based stats. Identities = 44/215 (20%), Positives = 92/215 (42%), Gaps = 10/215 (4%) Query: 40 LAAYMFLLIML-GFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 AA + L++++ N L + KKL+ NY L++LAVADL + L T Sbjct: 21 WAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTI 80 Query: 99 LHGY-FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENH-AIMG 156 + + C F L ++W L ++++RY+ + KP+ ++ A + Sbjct: 81 MFEAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIK 140 Query: 157 VAFTWVMALACAAP-PLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIP 215 + W++++ A P P+ G + +C + + F+++ + F P Sbjct: 141 ITVVWLISIGIAIPVPIKGIETDVDNPNNITCVL------TKERFGDFMLFGSLAAFFTP 194 Query: 216 LIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 L ++ Y + +++ AA +++ T +V Sbjct: 195 LAIMIVTYFLTIHALQKKAADLEDNWETLNDNLKV 229 Score = 66.3 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 38/92 (41%), Gaps = 2/92 (2%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDF--GPIFMTIPAFF 294 Q+ T E+ ++++ I+ FL+ W P+ + + + + I + Sbjct: 316 QKYLVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQMLLEIFVWI 375 Query: 295 AKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 326 S+ NP++Y + NK FR+ + C Sbjct: 376 GYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR 407 >5ZKB-A nrPDB Length = 421 Score = 162 bits (409), Expect = 3e-40, Method: Composition-based stats. Identities = 46/217 (21%), Positives = 93/217 (42%), Gaps = 12/217 (5%) Query: 37 FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 ++A + L+ ++G N L + ++ L+T NY L +LA ADL + Sbjct: 28 IVLVAGSLSLVTIIG---NILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTL 84 Query: 97 TSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAIM 155 ++ GY+ GP C+L + + +L++++ +RY V KP++ + A M Sbjct: 85 YTVIGYWPLGPVVCDLWLALDYVVSNARVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGM 144 Query: 156 GVAFTWVMALACAAPPLVGWS--RYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFI 213 +A WV++ AP ++ W + C I +++ N + + F Sbjct: 145 MIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS------NAAVTFGTAIAAFY 198 Query: 214 IPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 +P+I++ Y + K A +++ T +V Sbjct: 199 LPVIIMTVLYWHISRASKSRIADLEDNWETLNDNLKV 235 Score = 85.1 bits (209), Expect = 4e-17, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Query: 243 TQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYN 302 EK+VTR ++ +++AF+I W PY V I T TI + ++ N Sbjct: 327 PPSREKKVTRTILAILLAFIITWAPYN-VMVLINTFCAPCIPNTVWTIGYWLCYINSTIN 385 Query: 303 PVIYIMMNKQFRNCMVTTLCCGKNPLG 329 P Y + N F+ L C +G Sbjct: 386 PACYALCNATFKKTFKHLLMCHYKNIG 412 >6HLP-A nrPDB Length = 520 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 45/226 (19%), Positives = 95/226 (42%), Gaps = 2/226 (0%) Query: 27 PQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 P ++ WQ + AA ++++ N + +++ + HK++RT NY L+N A A+ M Sbjct: 22 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNAAFAEASM 81 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 ++H + +G C FF +++S+ +A +RY+ + P+ Sbjct: 82 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAIFASIYSMTAVAFDRYMAIIHPLQP- 140 Query: 147 RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 R + + WV+AL A P + + C I++ + + + I Sbjct: 141 RLSLTATKVVICVIWVLALLLAFPQGYYSTTETMP-SRVVCKIEWPEHPNKIYEKVYHIC 199 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 + V+ + +PL+VI + Y + T++ + + R Sbjct: 200 VTVLIYFLPLLVIGYLYTVVGITLRASGIDCSFWNESYLTGSRDER 245 Score = 67.8 bits (164), Expect = 8e-12, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 4/78 (5%) Query: 259 IAFLICWLPYAGVAFYIFTHQGS---DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRN 315 F ICWLP+ + + F + A +S +YNP+IY +N +FR Sbjct: 440 CTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRL 499 Query: 316 CMVTTL-CCGKNPLGDDE 332 CC GD E Sbjct: 500 GFKHAFRCCPFISAGDYE 517 >6CM4-A nrPDB Length = 430 Score = 161 bits (407), Expect = 5e-40, Method: Composition-based stats. Identities = 46/198 (23%), Positives = 83/198 (41%), Gaps = 15/198 (7%) Query: 41 AAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLH 100 A + LLI + N L + K L+T NY++++LAVADL + +Y + Sbjct: 4 ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVV 63 Query: 101 GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF--GENHAIMGVA 158 G + F C++ + + +L ++I+RY V PM + + ++ Sbjct: 64 GEWKFSRIHCDIFVTLDVMMCTASALNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIS 123 Query: 159 FTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIV 218 WV++ + P L G + Q C I N +FV+Y +V F +P IV Sbjct: 124 IVWVLSFTISCPLLFGLN----NADQNECII---------ANPAFVVYSSIVSFYVPFIV 170 Query: 219 IFFCYGQLVFTVKEAAAQ 236 Y ++ ++ + Sbjct: 171 TLLVYIKIYIVLRRRRKR 188 Score = 84.7 bits (208), Expect = 5e-17, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%) Query: 243 TQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYN 302 +Q+ EK+ T+M I+ F+ICWLP+ + + H + P+ + + ++ N Sbjct: 351 SQQKEKKATQMAAIVAGVFIICWLPFF-ITHILNIHCDCNIPPVLYSAFTWLGYVNSAVN 409 Query: 303 PVIYIMMNKQFRNCMVTTLCC 323 P+IY N +FR + L C Sbjct: 410 PIIYTTFNIEFRKAFLKILHC 430 >3PBL-A nrPDB Length = 481 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 48/204 (23%), Positives = 86/204 (42%), Gaps = 17/204 (8%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 + A LI+ N L ++ + L+T NY++++LAVADL + +Y Sbjct: 39 AYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYL 98 Query: 98 SLHGY-FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF----RFGENH 152 + G + F C++ + ++W+L ++I+RY V P+ + Sbjct: 99 EVTGGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGTGQSSCRR 158 Query: 153 AIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHF 212 + + WV+A A + P L G++ G C I +N FVIY VV F Sbjct: 159 VALMITAVWVLAFAVSCPLLFGFNTT---GDPTVCSI---------SNPDFVIYSSVVSF 206 Query: 213 IIPLIVIFFCYGQLVFTVKEAAAQ 236 +P V Y ++ +K+ + Sbjct: 207 YLPFGVTVLVYARIYVVLKQRRRK 230 Score = 90.1 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 25/87 (28%), Positives = 41/87 (47%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ EK+ T+MV I++ AF++CWLP+ Q P + + + Sbjct: 388 DAYGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVN 447 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLCCGK 325 + NPVIY N +FR + L CG+ Sbjct: 448 SALNPVIYTTFNIEFRKAFLKILSCGR 474 >4U14-A nrPDB Length = 460 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 83/201 (41%), Gaps = 9/201 (4%) Query: 35 WQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTT 94 WQ +A L ++ N L + +K+L+T NY LL+LA ADL + Sbjct: 10 WQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLF 69 Query: 95 LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHA 153 + + G C+L + ++ +L+V++ +RY + +P++ + A Sbjct: 70 TTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRA 129 Query: 154 IMGVAFTWVMALACAAPPLVGWSRYIPEGMQC--SCGIDYYTPHEETNNESFVIYMFVVH 211 + + WV++ AP ++ W ++ + C I + + + + Sbjct: 130 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS------EPTITFGTAIAA 183 Query: 212 FIIPLIVIFFCYGQLVFTVKE 232 F +P+ ++ Y ++ ++ Sbjct: 184 FYMPVTIMTILYWRIYKETEK 204 Score = 75.1 bits (183), Expect = 4e-14, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 1/78 (1%) Query: 246 AEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVI 305 EK+ + + +++AF+I W PY + + T S + + + ++ NPV Sbjct: 368 KEKKAAQTLSAILLAFIITWTPYN-IMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVC 426 Query: 306 YIMMNKQFRNCMVTTLCC 323 Y + NK FR T L C Sbjct: 427 YALCNKTFRTTFKTLLLC 444 >5T1A-A nrPDB Length = 508 Score = 157 bits (398), Expect = 5e-39, Method: Composition-based stats. Identities = 41/215 (19%), Positives = 89/215 (41%), Gaps = 8/215 (3%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 +L L+ + GF N L + + + KKL+ + LLNLA++DL + S Sbjct: 54 LLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAH--S 111 Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR-FGENHAIMGV 157 +VFG C L +G ++ +++L I+RY+ + + + ++ Sbjct: 112 AANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTS 171 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 TW++A+ + P ++ +++ E CG + N I ++ ++PL+ Sbjct: 172 VITWLVAVFASVPGII-FTKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLL 226 Query: 218 VIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 ++ CY + K + + ++ + Sbjct: 227 IMVICYSGISRASKSRINIFEMLRIDEGLRLKIYK 261 Score = 72.8 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 33/91 (36%), Gaps = 8/91 (8%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY--------IFTHQGSDFGPIFMTI 290 ++ EK+ R++ ++I + + W PY V + + + + Sbjct: 401 DAYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQV 460 Query: 291 PAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 T NP+IY + ++FR + Sbjct: 461 TETLGMTHCCINPIIYAFVGEKFRRYLSVFF 491 >3UON-A nrPDB Length = 467 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 43/219 (19%), Positives = 92/219 (42%), Gaps = 12/219 (5%) Query: 37 FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLY 96 ++A + L+ ++G N L + ++ L+T NY L +LA ADL + Sbjct: 26 IVLVAGSLSLVTIIG---NILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTL 82 Query: 97 TSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAIM 155 ++ GY+ GP C+L + ++ +L++++ +RY V KP++ + A M Sbjct: 83 YTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGM 142 Query: 156 GVAFTWVMALACAAPPLVGWS--RYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFI 213 +A WV++ AP ++ W + C I +++ N + + F Sbjct: 143 MIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS------NAAVTFGTAIAAFY 196 Query: 214 IPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 +P+I++ Y + K + + ++ + Sbjct: 197 LPVIIMTVLYWHISRASKSRINIFEMLRIDEGLRLKIYK 235 Score = 84.7 bits (208), Expect = 5e-17, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ EK+VTR ++ +++AF+I W PY V I T TI + + Sbjct: 375 DAYPPPSREKKVTRTILAILLAFIITWAPYN-VMVLINTFCAPCIPNTVWTIGYWLCYIN 433 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG 329 + NP Y + N F+ L C +G Sbjct: 434 STINPACYALCNATFKKTFKHLLMCHYKNIG 464 >5UVI-A nrPDB Length = 447 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 46/239 (19%), Positives = 96/239 (40%), Gaps = 9/239 (3%) Query: 19 VVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLN 78 +V + ++ S+ + +L N L + + L+ NY +++ Sbjct: 13 LVFADYKDDDDGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVS 72 Query: 79 LAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVV 138 LA AD+ G ++ F GC F + + +++SL+ +AI+RY+ Sbjct: 73 LAAADI--AVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIA 130 Query: 139 VCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSRY--IPEGMQCSCGI---DYY 192 + P+ N A +A WV++ A P++GW+ EG S G Sbjct: 131 IRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVA 190 Query: 193 TPHEETNNESFVIY-MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 E+ ++++Y F ++PL+++ Y ++ + A +++ T +V Sbjct: 191 CLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLADLEDNWETLNDNLKV 249 Score = 80.1 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 1/86 (1%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIF-MTIPAFFA 295 + + +T + E + + I+V F +CWLP + + F P++ M + + Sbjct: 339 LERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLS 398 Query: 296 KTSAVYNPVIYIMMNKQFRNCMVTTL 321 T++V NP IY ++FR + Sbjct: 399 HTNSVVNPFIYAYRIREFRQTFRKII 424 >6BQH-A nrPDB Length = 452 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 44/197 (22%), Positives = 86/197 (43%), Gaps = 11/197 (5%) Query: 57 LTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGY-FVFGPTGCNLEGF 115 L + KKL NY L++LA+AD+ + +L L+ Y + C + Sbjct: 60 LVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWIS 119 Query: 116 FATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMALACAAP-PLV 173 L ++ L ++++RYV + P+ + RF AIM +A W +++ + P P++ Sbjct: 120 LDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVI 179 Query: 174 GWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEA 233 G + + + N+ +FV+ V F IPL ++ Y ++ ++ Sbjct: 180 GLRDEEKVFVNNTTCV--------LNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQ 231 Query: 234 AAQQQESATTQKAEKEV 250 AA +++ T +V Sbjct: 232 AADLEDNWETLNDNLKV 248 Score = 63.6 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 35/85 (41%), Gaps = 3/85 (3%) Query: 245 KAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPI---FMTIPAFFAKTSAVY 301 E++ ++++ I+ FLI W P+ + S + + + + ++ Sbjct: 342 NNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVNSGI 401 Query: 302 NPVIYIMMNKQFRNCMVTTLCCGKN 326 NP++Y + NK +R L C Sbjct: 402 NPLVYTLFNKIYRRAFSNYLRCNYK 426 >4U15-A nrPDB Length = 418 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 83/201 (41%), Gaps = 9/201 (4%) Query: 35 WQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTT 94 WQ +A L ++ N L + +K+L+T NY LL+LA ADL + Sbjct: 10 WQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLF 69 Query: 95 LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHA 153 + + G C+L + ++ +L+V++ +RY + +P++ + A Sbjct: 70 TTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRA 129 Query: 154 IMGVAFTWVMALACAAPPLVGWSRYIPEGMQC--SCGIDYYTPHEETNNESFVIYMFVVH 211 + + WV++ AP ++ W ++ + C I + + + + Sbjct: 130 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS------EPTITFGTAIAA 183 Query: 212 FIIPLIVIFFCYGQLVFTVKE 232 F +P+ ++ Y ++ ++ Sbjct: 184 FYMPVTIMTILYWRIYKETEK 204 Score = 73.6 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 1/78 (1%) Query: 246 AEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVI 305 EK+ + + +++AF+I W PY + + T S + + + ++ NPV Sbjct: 325 KEKKAAQTLSAILLAFIITWTPYN-IMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVC 383 Query: 306 YIMMNKQFRNCMVTTLCC 323 Y + NK FR T L C Sbjct: 384 YALCNKTFRTTFKTLLLC 401 >5N2S-A nrPDB Length = 436 Score = 154 bits (389), Expect = 6e-38, Method: Composition-based stats. Identities = 46/295 (15%), Positives = 105/295 (35%), Gaps = 14/295 (4%) Query: 45 FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFV 104 L+ ++ P N L ++ ++ LR +++LAVAD+ + + ++ Sbjct: 124 VLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVLVGALVIPLAILINIGPQTY 183 Query: 105 FGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVM 163 F C + + + ++ +L+ +A++RY+ V P+ A + +A W++ Sbjct: 184 F--HTCLMVACPVLILAQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWIL 241 Query: 164 ALACAAPPLVGWSR-----------YIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHF 212 + P+ GW+ C + E +F +++ Sbjct: 242 SFVVGLTPMFGWNNLSAVERAWAAAGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLL 301 Query: 213 IIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVA 272 ++ LI + K+ +A + E ++ + ++ F + WLP + Sbjct: 302 LMVLIYLEVFALIRKQLNKKVSASSGDPQKYYGKELKIAKSAALIAFLFALSWLPLHILN 361 Query: 273 FYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNP 327 I I F A ++ NP++Y ++FR + Sbjct: 362 CITLFCPSCHKPSILTYIAIFLAHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRS 416 >5CXV-A nrPDB Length = 515 Score = 154 bits (389), Expect = 6e-38, Method: Composition-based stats. Identities = 43/203 (21%), Positives = 84/203 (41%), Gaps = 9/203 (4%) Query: 34 PWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT 93 PWQ + + LL + N L L + +L+T NY LL+LA ADL + Sbjct: 47 PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNL 106 Query: 94 TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENH 152 L G++ G C+L + + ++ +L++++ +RY V +P+S + Sbjct: 107 YTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRR 166 Query: 153 AIMGVAFTWVMALACAAPPLVGWSRYIPEGMQC--SCGIDYYTPHEETNNESFVIYMFVV 210 A + + W+++ AP ++ W + E C I + + T + Sbjct: 167 AALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT------FGTAMA 220 Query: 211 HFIIPLIVIFFCYGQLVFTVKEA 233 F +P+ V+ Y ++ + Sbjct: 221 AFYLPVTVMCTLYWRIYRETENR 243 Score = 74.7 bits (182), Expect = 6e-14, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 246 AEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVI 305 EK+ R + +++AF++ W PY + + T + + ++ NP+ Sbjct: 408 KEKKAARTLSAILLAFILTWTPYN-IMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMC 466 Query: 306 YIMMNKQFRNCMVTTLCCG 324 Y + NK FR+ L C Sbjct: 467 YALCNKAFRDTFRLLLLCR 485 >5XSZ-A nrPDB Length = 477 Score = 154 bits (389), Expect = 6e-38, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 90/203 (44%), Gaps = 3/203 (1%) Query: 33 EPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFT 92 + +++ + + ++ M+G N +Y+ + KLR ++NL V+DL V Sbjct: 24 DNFKYPLYSMVFSIVFMVGLITNVAAMYIFMCSLKLRNETTTYMMNLVVSDLLFVLT-LP 82 Query: 93 TTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGEN 151 ++ + + FG C L ++ L ++++R++ + P + + Sbjct: 83 LRVFYFVQQNWPFGSLLCKLSVSLFYTNMYGSILFLTCISVDRFLAIVYPFRSRGLRTKR 142 Query: 152 HAIMGVAFTWVMALACAAPP-LVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVV 210 +A + A WV+ L+ + P + S E SC ++ + +++ VI++ V Sbjct: 143 NAKIVCAAVWVLVLSGSLPTGFMLNSTNKLENNSISCFENFSSKEWKSHLSKVVIFIETV 202 Query: 211 HFIIPLIVIFFCYGQLVFTVKEA 233 F+IPL++ C ++ T++ Sbjct: 203 GFLIPLMLNVVCSAMVLQTLRRP 225 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFT--------HQGSDFGPIFM 288 + + +K++ RM+I+ + F C++PY + Sbjct: 381 RTGTWDAYLNKKKILRMIIVHLFIFCFCFIPYNVNLVFYSLVRTNTLKGCAAESVVRTIY 440 Query: 289 TIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 I A ++ ++P++Y ++ +N Sbjct: 441 PIALCIAVSNCCFDPIVYYFTSETIQNS 468 >5XJM-A nrPDB Length = 422 Score = 154 bits (389), Expect = 6e-38, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 91/212 (42%), Gaps = 1/212 (0%) Query: 40 LAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSL 99 + +++ ++GF +N + + + K + + + NLAVADL ++ Y S Sbjct: 14 IPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSY 73 Query: 100 HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAF 159 ++FGP C + G F TL +++ + ++++RY V P + R A V Sbjct: 74 RYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL 133 Query: 160 TWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFV-IYMFVVHFIIPLIV 218 W MA + P E + + I + P + + + + ++ FIIPLI Sbjct: 134 VWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIF 193 Query: 219 IFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 I CY + + + A +++ T +V Sbjct: 194 IATCYFGIRKHLLKTNADLEDNWETLNDNLKV 225 Score = 70.5 bits (171), Expect = 9e-13, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 238 QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFY--------IFTHQGSDFGPIFMT 289 Q+ + +V +M +V+AF+ICWLP+ + F I + + + + Sbjct: 312 QKYLKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALP 371 Query: 290 IPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 T++ NP +Y + +F+ + + Sbjct: 372 FAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF 403 >5DSG-A nrPDB Length = 422 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 83/202 (41%), Gaps = 9/202 (4%) Query: 36 QFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL 95 + +A L ++ N L + +++L+T NY L +LA ADL + Sbjct: 12 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 71 Query: 96 YTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGENHAI 154 + GY+ G C+L + ++ +L++++ +RY V KP++ R A Sbjct: 72 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 131 Query: 155 MGVAFTWVMALACAAPPLVGWSRYIPEGM--QCSCGIDYYTPHEETNNESFVIYMFVVHF 212 + +A WV++ AP ++ W + + C I + + N + + F Sbjct: 132 LMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLS------NPAVTFGTAIAAF 185 Query: 213 IIPLIVIFFCYGQLVFTVKEAA 234 +P++++ Y + + Sbjct: 186 YLPVVIMTVLYIHISLASRSRV 207 Score = 80.9 bits (198), Expect = 8e-16, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ E++VTR + +++AF++ W PY V + T S +I + + Sbjct: 322 DAYQMAARERKVTRTIFAILLAFILTWTPYN-VMVLVNTFCQSCIPDTVWSIGYWLCYVN 380 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG 329 + NP Y + N F+ L C +G Sbjct: 381 STINPACYALCNATFKKTFRHLLLCQYRNIG 411 >3RZE-A nrPDB Length = 452 Score = 148 bits (374), Expect = 3e-36, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 87/202 (43%), Gaps = 11/202 (5%) Query: 36 QFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTL 95 Q L + + ++ +N L LY +KL T N +++L+VADL + + Sbjct: 7 QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNI 66 Query: 96 YTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAI 154 L + G C + +++S+ +L I+RY V +P+ ++ + A Sbjct: 67 LYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRAS 126 Query: 155 MGVAFTWVMALACAAPPLVGWSRYIPE---GMQCSCGIDYYTPHEETNNESFVIYMFVVH 211 + W ++ P ++GW+ ++ + + C D+Y F + +++ Sbjct: 127 ATILGAWFLSFLWVIP-ILGWNHFMQQTSVRREDKCETDFYDVTW------FKVMTAIIN 179 Query: 212 FIIPLIVIFFCYGQLVFTVKEA 233 F +P +++ + Y ++ V++ Sbjct: 180 FYLPTLLMLWFYAKIYKAVRQH 201 Score = 75.9 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ E++ + + ++ AF++CW+PY I + + M + + Sbjct: 360 DAYLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHM-FTIWLGYIN 418 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLCCG 324 + NP+IY + N+ F+ L Sbjct: 419 STLNPLIYPLCNENFKKTFKRILHIR 444 >5GLH-A nrPDB Length = 498 Score = 145 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 76/188 (40%), Gaps = 6/188 (3%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 L+ +LG N LY+ ++K +R N ++ +LA+ DL + +Y L + F Sbjct: 48 LVFVLGIIGNSTLLYIIYKNKCMRNGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPF 107 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMA 164 G C L F I + SL L+I+RY V G + + WV++ Sbjct: 108 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 167 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI-----YMFVVHFIIPLIVI 219 + A P +G+ + I P ++T F ++F +F +PL + Sbjct: 168 VVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYATAKDWWLFSFYFCLPLAIT 227 Query: 220 FFCYGQLV 227 F Y + Sbjct: 228 AFFYTLMT 235 Score = 60.1 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Query: 243 TQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFT---------HQGSDFGPIFMTIPAF 293 K +EV + V +V+ F +CWLP T + F + I Sbjct: 405 HLKQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDPNRCELLSFLLVLDYIGIN 464 Query: 294 FAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 A ++ NP+ +++K+F+N + LCC Sbjct: 465 MASLNSCANPIALYLVSKRFKNAFKSALCC 494 >4ZJC-A nrPDB Length = 553 Score = 144 bits (363), Expect = 6e-35, Method: Composition-based stats. Identities = 39/211 (18%), Positives = 95/211 (45%), Gaps = 6/211 (2%) Query: 24 FEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD 83 + Y + +++ ++AAY+ + ++ N L ++ +RT NY ++NL++AD Sbjct: 42 YLWRDYLYPKQYEWVLIAAYVAVFVVA-LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLAD 100 Query: 84 LFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM 143 + + +L + ++FG C + + + +A+ +L +A++R+ +C P+ Sbjct: 101 VLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPL 160 Query: 144 SNFRFGENHAIMGVAFTWVMALACAAP--PLVGWSRYIPEGMQCS--CGIDYYTPHEETN 199 F+ A + W ++LA P ++ S +PE + + ++ Sbjct: 161 L-FKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLY 219 Query: 200 NESFVIYMFVVHFIIPLIVIFFCYGQLVFTV 230 + + F+V ++ PL ++ Y Q+ + Sbjct: 220 PKIYHSCFFIVTYLAPLGLMAMAYFQIFRKL 250 Score = 67.8 bits (164), Expect = 8e-12, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 41/98 (41%), Gaps = 6/98 (6%) Query: 232 EAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTH----QGSDFGPIF 287 + + +A ++ +M++++++ F +C+LP + + Q SD ++ Sbjct: 441 NCKKRAMSFSKQMRARRKTAKMLMVVLLVFALCYLPISVLNILKRVFGMFRQASDREAVY 500 Query: 288 MTIP--AFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 + ++ NP+IY ++ +FR C Sbjct: 501 ACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 538 >5WF6-A nrPDB Length = 504 Score = 144 bits (362), Expect = 8e-35, Method: Composition-based stats. Identities = 47/251 (18%), Positives = 98/251 (39%), Gaps = 14/251 (5%) Query: 9 FYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKL 68 + + + + P AP + + LA + +L N L + + L Sbjct: 14 VFADYKDDDDAMGQPVGAPPIMGSSVYITVELA-----IAVLAILGNVLVCWAVWLNSNL 68 Query: 69 RTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSL 128 + NY +++LA AD+ G ++ F GC F + + A++SL Sbjct: 69 QNVTNYFVVSLAAADI--AVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSAIFSL 126 Query: 129 VVLAIERYVVVCKPMS-NFRFGENHAIMGVAFTWVMALACAAPPLVGWSRY--IPEGMQC 185 + +AI+RY+ + P+ N A +A WV++ A P++GW+ EG Sbjct: 127 LAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNH 186 Query: 186 SCGI---DYYTPHEETNNESFVIY-MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESA 241 S G E+ ++++Y F ++PL+++ Y ++ + + Sbjct: 187 SQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLNIFEMLR 246 Query: 242 TTQKAEKEVTR 252 + ++ + Sbjct: 247 IDEGLRLKIYK 257 Score = 77.8 bits (190), Expect = 7e-15, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 240 SATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIF-MTIPAFFAKTS 298 +T + E + + I+V F +CWLP + + F P++ M + + T+ Sbjct: 399 YRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTN 458 Query: 299 AVYNPVIYIMMNKQFRNCMVTTL 321 +V NP IY ++FR + Sbjct: 459 SVVNPFIYAYRIREFRQTFRKII 481 >6D9H-R nrPDB Length = 389 Score = 143 bits (361), Expect = 9e-35, Method: Composition-based stats. Identities = 50/304 (16%), Positives = 113/304 (37%), Gaps = 17/304 (5%) Query: 32 AEPWQFSMLAAYM---FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVF 88 P + AAY+ L+ ++ P N L ++ ++ LR +++LAVAD+ + Sbjct: 56 PPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 115 Query: 89 GGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF 148 + ++ F C + + + ++ +L+ +A++RY+ V P+ Sbjct: 116 LVIPLAILINIGPQTYF--HTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMV 173 Query: 149 -GENHAIMGVAFTWVMALACAAPPLVGWSR-----------YIPEGMQCSCGIDYYTPHE 196 A + +A W+++ P+ GW+ C + E Sbjct: 174 VTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISME 233 Query: 197 ETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVII 256 +F +++ ++ LI + Y K+ +A + E ++ + + + Sbjct: 234 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLAL 293 Query: 257 MVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNC 316 ++ F + WLP + I I F ++ NP++Y ++FR Sbjct: 294 ILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVT 353 Query: 317 MVTT 320 + Sbjct: 354 FLKI 357 >5GLI-A nrPDB Length = 464 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 76/188 (40%), Gaps = 6/188 (3%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 L+ +LG N LY+ ++K +R N ++ +LA+ DL + +Y L + F Sbjct: 48 LVFVLGIIGNSTLLYIIYKNKCMRNGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPF 107 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMA 164 G C L F I + SL L+I+RY V G + + WV++ Sbjct: 108 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 167 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI-----YMFVVHFIIPLIVI 219 + A P +G+ + I P ++T F ++F +F +PL + Sbjct: 168 VVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYATAKDWWLFSFYFCLPLAIT 227 Query: 220 FFCYGQLV 227 F Y + Sbjct: 228 AFFYTLMT 235 Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Query: 243 TQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFT---------HQGSDFGPIFMTIPAF 293 K +EV + V +V+ F +CWLP T + F + I Sbjct: 362 HLKQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDPNRCELLSFLLVLDYIGIN 421 Query: 294 FAKTSAVYNPVIYIMMNKQFRNCMVTTLCC 323 A ++ NP+ +++K+F+N + LCC Sbjct: 422 MASLNSCANPIALYLVSKRFKNAFKSALCC 451 >3OE9-A nrPDB Length = 499 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 41/208 (19%), Positives = 76/208 (36%), Gaps = 7/208 (3%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98 L ++ + G N L + V KKLR+ + L+L+VADL V + Sbjct: 50 FLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAV--D 107 Query: 99 LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHA-IMGV 157 + FG C T+ ++W L ++++RY+ + ++ R + A + Sbjct: 108 AVANWYFGNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAIVHATNSQRPRKLLAEKVVY 167 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 W+ AL P + + + + C Y + I V I+P I Sbjct: 168 VGVWIPALLLTIPDFIFANVSEADD-RYICDRFYPNDLWVVVFQFQHIM---VGLILPGI 223 Query: 218 VIFFCYGQLVFTVKEAAAQQQESATTQK 245 VI CY ++ + + + Sbjct: 224 VILSCYCIIISKLSHNIFEMLRIDEGLR 251 Score = 65.5 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 37/88 (42%), Gaps = 9/88 (10%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAG------VAFYIFTHQGSDFGPI---FMTIPAFFAKT 297 +++ + +I+++AF CWLPY QG +F +++I A Sbjct: 405 KRKALKPTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFF 464 Query: 298 SAVYNPVIYIMMNKQFRNCMVTTLCCGK 325 NP++Y + +F+ L G+ Sbjct: 465 HCCLNPILYAFLGAKFKTSAQHALTSGR 492 >5WIV-A nrPDB Length = 422 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 87/212 (41%), Gaps = 16/212 (7%) Query: 45 FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGY-F 103 LLI N L + L+TP N +++LA ADL + +Y+ + G + Sbjct: 46 VLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAW 105 Query: 104 VFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWV 162 + P C+ + ++++L ++++R+V V P+ R G ++ + TW+ Sbjct: 106 LLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWL 165 Query: 163 MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFC 222 ++ A AAP L G + C ++ + +V+Y V F +P ++ Sbjct: 166 LSAAVAAPVLCGLNDVRGRD-PAVCRLE---------DRDYVVYSSVCSFFLPCPLMLLL 215 Query: 223 YGQLVFTVKEA----AAQQQESATTQKAEKEV 250 Y ++ A +++ T +V Sbjct: 216 YWATFRGLQRWEVARRADLEDNWETLNDNLKV 247 Score = 91.3 bits (225), Expect = 6e-19, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAK 296 Q+ A E++ R++ ++V AFL+CW P+ V P ++ + Sbjct: 334 QKYLAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGY 393 Query: 297 TSAVYNPVIYIMMNKQFRNCMVTTL--CC 323 ++ NPVIY + N +FRN L CC Sbjct: 394 VNSALNPVIYTVFNAEFRNVFRKALRACC 422 >5NDD-A nrPDB Length = 619 Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 80/214 (37%), Gaps = 5/214 (2%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 L ++ ++ P N + L+V + K + P + NLA+ADL V Y Sbjct: 205 VFLPIVYTIVFVVALPSNGMALWVFLFRTKKKAPAVIYMANLALADLLSVIWFPLKIAYH 264 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGV 157 +++G CN+ F ++ L L+++R + PM + R N AI Sbjct: 265 IHGNNWIYGEALCNVLIGFFYANMYCSILFLTCLSVQRAWEIVNPMGHSRKKANIAIGIS 324 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNE-SFVIYMFVVHFIIPL 216 W++ L P V +Q + D + ++ + + + F+ P Sbjct: 325 LAIWLLILLVTIPLYVVKQTIFIPALQITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPA 384 Query: 217 IVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 + Y ++ + A +++ T +V Sbjct: 385 FLTASAYVLMIRAL----ADLEDNWETLNDNLKV 414 Score = 53.9 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 37/91 (40%), Gaps = 3/91 (3%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLP---YAGVAFYIFTHQGSDFGPIFMTIPAF 293 Q+ ++K K ++ + + +LIC+ P V +++ QG + Sbjct: 501 QKYLENSEKKRKRAIKLAVTVAAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALC 560 Query: 294 FAKTSAVYNPVIYIMMNKQFRNCMVTTLCCG 324 + ++ +P +Y ++ FR+ L C Sbjct: 561 LSTLNSCIDPFVYYFVSHDFRDHAKNALLCR 591 >5NJ6-A nrPDB Length = 437 Score = 119 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 80/214 (37%), Gaps = 5/214 (2%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 L ++ ++ P N + L+V + K + P + NLA+ADL V Y Sbjct: 23 VFLPIVYTIVFVVALPSNGMALWVFLFRTKKKAPAVIYMANLALADLLSVIWFPLKIAYH 82 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGV 157 +++G CN+ F ++ L L+++R + PM + R N AI Sbjct: 83 IHGNNWIYGEALCNVLIGFFYANMYCSILFLTCLSVQRAWEIVNPMGHSRKKANIAIGIS 142 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNE-SFVIYMFVVHFIIPL 216 W++ L P V +Q + D + ++ + + + F+ P Sbjct: 143 LAIWLLILLVTIPLYVVKQTIFIPALQITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPA 202 Query: 217 IVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 + Y ++ + A +++ T +V Sbjct: 203 FLTASAYVLMIRAL----ADLEDNWETLNDNLKV 232 Score = 52.0 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 37/91 (40%), Gaps = 3/91 (3%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLP---YAGVAFYIFTHQGSDFGPIFMTIPAF 293 Q+ ++K K ++ + + +LIC+ P V +++ QG + Sbjct: 319 QKYLENSEKKRKRAIKLAVTVAAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALC 378 Query: 294 FAKTSAVYNPVIYIMMNKQFRNCMVTTLCCG 324 + ++ +P +Y ++ FR+ L C Sbjct: 379 LSTLNSCIDPFVYYFVSHDFRDHAKNALLCR 409 >5U09-A nrPDB Length = 508 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 19/220 (8%) Query: 15 NKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFL-LIMLGFPINFLTLYVTVQHKKLRT-PL 72 + F + ++ + A + L L N L L V + + LR P Sbjct: 5 EENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPS 64 Query: 73 NYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFF---ATLGGEIALWSLV 129 + + +LAVADL G +Y+ + + N+ F T ++ SL Sbjct: 65 YHFIGSLAVADLL----GSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLF 120 Query: 130 VLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCG 188 + AI+RY+ + +P++ R A++ W +A+ A PL+GW+ E +Q C Sbjct: 121 LAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWN---CEKLQSVCS 177 Query: 189 IDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVF 228 + +E+++++ V ++ L+ I + Y +++ Sbjct: 178 DIFPH-----IDETYLMFWIGVTSVL-LLFIVYAYMYILW 211 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 31/73 (42%) Query: 249 EVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIM 308 + + ++++++ +ICW P + Y + + + ++ NP+IY + Sbjct: 417 RLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYAL 476 Query: 309 MNKQFRNCMVTTL 321 +K R+ + Sbjct: 477 RSKDLRHAFRSMF 489 >3V2Y-A nrPDB Length = 520 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 42/206 (20%), Positives = 80/206 (38%), Gaps = 10/206 (4%) Query: 28 QYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMV 87 + + + L+ N L + KK P+ Y + NLA++DL Sbjct: 54 NISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAG 113 Query: 88 FGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR 147 +T L S + P L + +++SL+ +AIERY+ + K + Sbjct: 114 V-AYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNG 172 Query: 148 FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYM 207 + ++ WV++L P++GW+ I CS + Y H ++++ Sbjct: 173 SNNFRLFLLISACWVISLILGGLPIMGWN-CISALSSCSTVLPLYHKH-------YILFC 224 Query: 208 FVVHFIIPLIVIFFCYGQLVFTVKEA 233 V F + L+ I Y ++ V+ Sbjct: 225 TTV-FTLLLLSIVILYCRIYSLVRTR 249 Score = 51.6 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 32/84 (38%), Gaps = 3/84 (3%) Query: 240 SATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQ--GSDFGPIFMTIPAFFAKT 297 A+ + + VII++ F+ CW P + + D A Sbjct: 409 YASRSSENVALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDI-LFRAEYFLVLAVL 467 Query: 298 SAVYNPVIYIMMNKQFRNCMVTTL 321 ++ NP+IY + NK+ R + + Sbjct: 468 NSGTNPIIYTLTNKEMRRAFIRIM 491 >5XRA-A nrPDB Length = 438 Score = 118 bits (295), Expect = 5e-27, Method: Composition-based stats. Identities = 47/219 (21%), Positives = 89/219 (40%), Gaps = 19/219 (8%) Query: 22 SPFEAPQYYLAEPWQFSMLAAYMFL-LIMLGFPINFLTLYVTVQHKKLRT-PLNYILLNL 79 F + ++ + A + L L N L L V + + LR P + + +L Sbjct: 2 ENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSL 61 Query: 80 AVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFF---ATLGGEIALWSLVVLAIERY 136 AVADL G +Y+ + + N+ F T ++ SL + AI+RY Sbjct: 62 AVADLL----GSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRY 117 Query: 137 VVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPH 195 + + +P++ R A++ W +A+ A PL+GW+ E +Q C + Sbjct: 118 ISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWN---CEKLQSVCSDIFPH-- 172 Query: 196 EETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAA 234 + + ++ VV + L+ I + Y +++ A Sbjct: 173 --IDKTYLMFWIGVVSVL--LLFIVYAYMYILWKAHSHA 207 Score = 51.6 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 32/73 (43%) Query: 249 EVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIM 308 E+ + ++++++ +ICW P + Y + + + ++ NP+IY + Sbjct: 364 ELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYAL 423 Query: 309 MNKQFRNCMVTTL 321 +K R+ + Sbjct: 424 RSKDLRHAFRSMF 436 >3VW7-A nrPDB Length = 484 Score = 115 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 42/230 (18%), Positives = 85/230 (36%), Gaps = 2/230 (0%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 E YL W + + + ++ P+N + + V + K++ P +L+LA AD+ Sbjct: 8 EDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADV 67 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144 V Y + FG C ++ + V++I+R++ V PM Sbjct: 68 LFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQ 127 Query: 145 NFRFGE-NHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPH-EETNNES 202 + + A W +A+A P L+ G+ + D + E Sbjct: 128 SLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLGITTCHDVLSETLLEGYYAY 187 Query: 203 FVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTR 252 + V F +PLI+ CY ++ + +A + + ++ + Sbjct: 188 YFSAFSAVFFFVPLIISTVCYVSIIRCLSSSANIFEMLRIDEGLRLKIYK 237 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 11/93 (11%), Positives = 35/93 (37%), Gaps = 4/93 (4%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAF----YIFTHQGSDFGPIFMTIPAFF 294 ++ + + + + F+IC+ P + ++ ++ + Sbjct: 377 DAYANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCV 436 Query: 295 AKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNP 327 + S +P+IY + + + + + LCC ++ Sbjct: 437 SSISCCIDPLIYYYASSECQRYVYSILCCKESS 469 >4Z36-A nrPDB Length = 459 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 42/224 (18%), Positives = 89/224 (39%), Gaps = 16/224 (7%) Query: 29 YYLAEPW--QFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86 +LA W ++ + + N L + +++ P+ Y++ NLA AD F Sbjct: 57 KHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFA 116 Query: 87 VFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF 146 F T + + T +G T ++ +L+ +AIER++ V + + Sbjct: 117 GLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDT-SLTASVANLLAIAIERHITVFRMQLHT 175 Query: 147 RFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIY 206 R ++ + W MA+ A P VGW+ C C I+ + + S++++ Sbjct: 176 RMSNRRVVVVIVVIWTMAIVMGAIPSVGWN--------CICDIENCSNMAPLYSCSYLVF 227 Query: 207 MFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 + + ++ +V+ Y + A +++ T +V Sbjct: 228 WAIFN-LVTFVVMVVLYAHIF----GYVADLEDNWETLNDNLKV 266 Score = 51.6 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 33/84 (39%), Gaps = 1/84 (1%) Query: 238 QESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKT 297 Q+ + + + V+I++ AF+ICW P + D + A+ Sbjct: 348 QKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDCCCPQCDVLA-YEKFFLLLAEF 406 Query: 298 SAVYNPVIYIMMNKQFRNCMVTTL 321 ++ NP+IY +K+ L Sbjct: 407 NSAMNPIIYSYRDKEMSATFRQIL 430 >5ZKP-A nrPDB Length = 466 Score = 111 bits (278), Expect = 4e-25, Method: Composition-based stats. Identities = 38/222 (17%), Positives = 89/222 (40%), Gaps = 7/222 (3%) Query: 22 SPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ---HKKLRTPLNYILLN 78 +P ++ +++++ ++ +LG N L+V + KK + ++N Sbjct: 2 APEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKF-NEIKIFMVN 60 Query: 79 LAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVV 138 L +AD+ + +Y G ++ CN+ G + ++ L V+ RY Sbjct: 61 LTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRYQA 120 Query: 139 VCKPMSNFRF-GENHAIMGVAFTWV-MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE 196 V +P+ + I WV + A + ++ + +P+ + +E Sbjct: 121 VTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGDVTRCFEHYE 180 Query: 197 ETNNESFVIYMFVV-HFIIPLIVIFFCYGQLVFTVKEAAAQQ 237 + + +I++F+V F + ++I FC ++ T+ A Sbjct: 181 KGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQAKAL 222 Score = 52.0 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 34/89 (38%), Gaps = 7/89 (7%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFT----HQGSDFG---PIFMTIPAFFAKTSA 299 ++ M ++ F+IC++P+ V Q S F + T+ Sbjct: 369 KRRDLWMACTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNC 428 Query: 300 VYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 V NPVIY + K+FR + ++ Sbjct: 429 VLNPVIYCFLTKKFRKHLTEKFYSMRSSR 457 >4GRV-A nrPDB Length = 510 Score = 110 bits (276), Expect = 6e-25, Method: Composition-based stats. Identities = 41/202 (20%), Positives = 78/202 (38%), Gaps = 19/202 (9%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLN---YILLNLAVADLFMVFGGFTTT 94 ++ A L ++G N +TL+ + K L++ + Y L +LA++DL ++ Sbjct: 33 VLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVE 92 Query: 95 LYTSL--HGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGEN 151 LY + H + FG GC F ++ L++ RY+ +C P + Sbjct: 93 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAICHPFKAKTLMSRS 152 Query: 152 HAIMGVAFTWVMALACAAPPLV-------GWSRYIPEGMQCSCGIDYYTPHEETNNESFV 204 ++ W+ + A P L P G+ C+ +D T +F+ Sbjct: 153 RTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFM 212 Query: 205 IYMFVVHFIIPLIVIFFCYGQL 226 F+ P++VI + Sbjct: 213 ------SFLFPMLVISILNTVI 228 Score = 80.9 bits (198), Expect = 8e-16, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 7/86 (8%) Query: 245 KAEKEVTRMVIIMVIAFLICWLPYAGVAF---YIFTHQGS----DFGPIFMTIPAFFAKT 297 +A + + +VIAF++CWLPY YI Q + DF F + A Sbjct: 402 QALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALAYA 461 Query: 298 SAVYNPVIYIMMNKQFRNCMVTTLCC 323 S+ NP++Y +++ FR ++TL C Sbjct: 462 SSAINPILYNLVSANFRQVFLSTLAC 487 >5ZKQ-A nrPDB Length = 438 Score = 107 bits (267), Expect = 8e-24, Method: Composition-based stats. Identities = 37/215 (17%), Positives = 88/215 (40%), Gaps = 7/215 (3%) Query: 22 SPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ---HKKLRTPLNYILLN 78 +P ++ +++++ ++ +LG N L+V + KK + ++N Sbjct: 2 APEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKF-NEIKIFMVN 60 Query: 79 LAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVV 138 L +AD+ + +Y G ++ CN+ G + ++ L V+ RY Sbjct: 61 LTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRYQA 120 Query: 139 VCKPMSNFRF-GENHAIMGVAFTWV-MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE 196 V +P+ + I WV + A + ++ + +P+ + +E Sbjct: 121 VTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGDVTRCFEHYE 180 Query: 197 ETNNESFVIYMFVV-HFIIPLIVIFFCYGQLVFTV 230 + + +I++F+V F + ++I FC ++ T+ Sbjct: 181 KGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTL 215 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 34/89 (38%), Gaps = 7/89 (7%) Query: 247 EKEVTRMVIIMVIAFLICWLPYAGVAFYIFT----HQGSDFG---PIFMTIPAFFAKTSA 299 ++ M ++ F+IC++P+ V Q S F + T+ Sbjct: 341 KRRDLWMACTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNC 400 Query: 300 VYNPVIYIMMNKQFRNCMVTTLCCGKNPL 328 V NPVIY + K+FR + ++ Sbjct: 401 VLNPVIYCFLTKKFRKHLTEKFYSMRSSR 429 >5X33-A nrPDB Length = 523 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 26/212 (12%), Positives = 74/212 (34%), Gaps = 5/212 (2%) Query: 25 EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL 84 + + + + + + +++G P N ++ ++ + R+ +++ Sbjct: 7 DDDDKEFSNTFIPLLAMILLSVSMVVGLPGNTFVVWSILKRMRKRSVTA-LMVLNLALAD 65 Query: 85 FMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144 V L+ G + FG GC L + + ++ + ++++R + V P Sbjct: 66 LAVLLTAPFFLHFLTWGTWSFGLAGCRLCHYICGVSMYASVLLITAMSLDRSLAVASPFL 125 Query: 145 NFR-FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESF 203 + + + A + W + A P L C Y + + + F Sbjct: 126 SQKVRTKTAARWLLVGIWGASFLLATPVLAFRKVVKLTNETDLCLAVYPSDRHKAFHLLF 185 Query: 204 VIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAA 235 + F++P +++ Y + ++ + Sbjct: 186 EAFT---GFVVPFLIVVASYADISRRLRARGS 214 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 33/93 (35%), Gaps = 7/93 (7%) Query: 225 QLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI-------FT 277 +++ T + S + + R+V+I+++AF WLPY V Sbjct: 363 RVITTFRTGTWDAYGSGSRFHRRRRTGRLVVIIILAFAAFWLPYHVVDLVEGSRVLAGTL 422 Query: 278 HQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMN 310 Q + A S+ NP++Y Sbjct: 423 DQSKQQLRNARKVCIALAFLSSSVNPLLYACAG 455 >5UEN-A nrPDB Length = 416 Score = 104 bits (260), Expect = 5e-23, Method: Composition-based stats. Identities = 39/229 (17%), Positives = 95/229 (41%), Gaps = 12/229 (5%) Query: 32 AEPWQFSMLAAYM---FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVF 88 P + AAY+ L+ ++ P N L ++ ++ LR +++LAVAD+ + Sbjct: 2 PPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 61 Query: 89 GGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR- 147 + ++ F C + + + ++ +L+ +A++RY+ V P+ Sbjct: 62 LVIPLAILINIGPQTYF--HTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMV 119 Query: 148 FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYM 207 A + +A W+++ P+ GW+ + P + E + Sbjct: 120 VTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAAAGSMGEPVIKCEFEKVISME 179 Query: 208 FVVHF------IIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEV 250 ++V+F + PL+++ Y ++ + +++ A +++ T +V Sbjct: 180 YMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLADLEDNWETLNDNLKV 228 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 34/84 (40%) Query: 237 QQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAK 296 + + +T + E ++ + + +++ F + WLP + I I F Sbjct: 318 LERARSTLQKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTH 377 Query: 297 TSAVYNPVIYIMMNKQFRNCMVTT 320 ++ NP++Y ++FR + Sbjct: 378 GNSAMNPIVYAFRIQKFRVTFLKI 401 >6D26-A nrPDB Length = 470 Score = 104 bits (260), Expect = 5e-23, Method: Composition-based stats. Identities = 35/198 (17%), Positives = 74/198 (37%), Gaps = 10/198 (5%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105 L +LG N + L+V + +T + +L+LA++DL T + ++ + Sbjct: 42 LASLLGLVENGVILFVVGCRMR-QTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWEL 100 Query: 106 GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFT-WVMA 164 G T C L L + + L ++++R + V +P+ A V W +A Sbjct: 101 GTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALA 160 Query: 165 LACAAPPLVGWSRYIPEGMQCSCGIDYY--------TPHEETNNESFVIYMFVVHFIIPL 216 + P V + C + + + + F++ F++PL Sbjct: 161 VLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQAALAVSKFLLAFLVPL 220 Query: 217 IVIFFCYGQLVFTVKEAA 234 +I + + ++ A Sbjct: 221 AIIASSHAAVSLRLQHRA 238 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 22/62 (35%), Gaps = 4/62 (6%) Query: 264 CWLPYAGVAFY-IFTHQGSDFGPIFM---TIPAFFAKTSAVYNPVIYIMMNKQFRNCMVT 319 CW PY + H P+ A ++V NPV+Y++ + Sbjct: 383 CWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRR 442 Query: 320 TL 321 +L Sbjct: 443 SL 444 >4NTJ-A nrPDB Length = 466 Score = 97.8 bits (242), Expect = 7e-21, Method: Composition-based stats. Identities = 32/217 (14%), Positives = 67/217 (30%), Gaps = 7/217 (3%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYT 97 + +L +G N L + + Q + + L N ++DL M+ L Sbjct: 35 VLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI-IFLKNTVISDLLMILTFPFKILSD 93 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENH-AIMG 156 + G C + I++ L ++ I+RY +P A + Sbjct: 94 AKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKIL 153 Query: 157 VAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPL 216 W + P ++ +R + C + I + F I Sbjct: 154 SVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVI--FWINF 211 Query: 217 IVIFFCYGQLVFTVKE---AAAQQQESATTQKAEKEV 250 +++ CY + + A +++ T +V Sbjct: 212 LIVIVCYTLITKELYRSYVRTADLEDNWETLNDNLKV 248 Score = 74.3 bits (181), Expect = 8e-14, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 41/108 (37%), Gaps = 8/108 (7%) Query: 227 VFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPI 286 + T + A Q+ + K+V V I++ F IC++P+ Q D Sbjct: 326 LKTTRNAYIQKYLRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDC 385 Query: 287 FMTIPA--------FFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 326 + +A NP IY + K FRN +++ L C + Sbjct: 386 TAENTLFYVKESTLWLTSLNACLNPFIYFFLCKSFRNSLISMLKCPNS 433 >5ZTY-A nrPDB Length = 500 Score = 90.1 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 41/202 (20%), Positives = 80/202 (39%), Gaps = 14/202 (6%) Query: 36 QFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRT-PLNYILLNLAVADLFMVFGGFTTT 94 Q + +A LL +L N LY+ + +LR P + +LA+AD F + Sbjct: 31 QKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLALADFL-ASVVFACS 89 Query: 95 LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNF-RFGENHA 153 + V L+ T+ ++ SL++ AI+RY+ + P S A Sbjct: 90 FVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLAAIDRYLCLRYPPSYKALLTRGRA 149 Query: 154 IMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFI 213 ++ + WV++ + PL+GW+ C N+ + ++ + F+ Sbjct: 150 LVLLGIMWVLSALVSYLPLMGWTC---------CPRPCSELFPLIPNDYLLSWLLFIAFL 200 Query: 214 IPLIVIFFCYGQLVFTVKEAAA 235 I + YG +++ + A Sbjct: 201 --FSGIIYTYGHVLWKAHQHVA 220 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 36/84 (42%) Query: 239 ESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTS 298 ++ + + E+ + + +++ LICW P + + SD + + Sbjct: 379 DAYARMRLDVELAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLIN 438 Query: 299 AVYNPVIYIMMNKQFRNCMVTTLC 322 ++ NPVIY + +++ R+ L Sbjct: 439 SMVNPVIYALRSEEIRSSAHHCLA 462 >5YWY-A nrPDB Length = 332 Score = 85.1 bits (209), Expect = 4e-17, Method: Composition-based stats. Identities = 47/290 (16%), Positives = 99/290 (34%), Gaps = 11/290 (3%) Query: 46 LLIMLGFPINFLTLYVTVQHKKLRTPLNYILL--NLAVADLFMVFGGFTTTLYTSLHGYF 103 ++ + G N + + V + +K + + L L V DL T+ T + G + Sbjct: 26 VMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLLVTDLLGTLLVSPVTIATYMKGQW 85 Query: 104 VFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENH-AIMGVAFTWV 162 G C F L + +++ERY+ + + + A + + + Sbjct: 86 PGGQPLCEYSTFILLFFSLSRLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYA 145 Query: 163 MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFC 222 + A P +G + C ID T + Y ++ +++ Sbjct: 146 SNVLFCALPNMGLGSSRLQYPDTWCFID-----WTTQVTAHAAYSYMYAGFSSFLILATV 200 Query: 223 YGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSD 282 ++ +Q AE ++ ++I + LIC +P F +Q S Sbjct: 201 LCNVLVCGALLRMHRQFFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSL 260 Query: 283 FGPIFM---TIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG 329 + A + + +P IYI++ K + + + C +G Sbjct: 261 EREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIG 310 >6AK3-B nrPDB Length = 418 Score = 77.0 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 45/294 (15%), Positives = 102/294 (34%), Gaps = 29/294 (9%) Query: 42 AYMFLLIMLGFPINFLTLYVT---VQHKKLRTPLNYI--LLNLAVADLF-MVFGGFTTTL 95 A+ +++ GF N L + + + ++ + +++ + LA+ DL + + Sbjct: 15 AFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIV 74 Query: 96 YTSLHGYFVFGPT---GCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSN-FRFGEN 151 + C G T+ G +L+ +A+ER + + P Sbjct: 75 VYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTR 134 Query: 152 HAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE---ETNNESFVIYMF 208 + W+ +LA A P++G +Y + C I + ++N + + Sbjct: 135 ITRAVLLGVWLASLAFALLPVLGVGQYTVQWPGTWCFISTGRGGQGTSSSHNWGNLFFAS 194 Query: 209 VVHF--IIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVII----MVIAFL 262 F ++ L V F C + + + + ++ + +T I +++ Sbjct: 195 AFAFLGLLALTVTFSCNLATIKALVDRCRAKATASQSSAQWGRITTETAIQLMGIMLVLS 254 Query: 263 ICWLPYAGVAFYIFTHQGS----------DFGPIFMTIPAFFAKTSAVYNPVIY 306 +CW P + + Q S F I A + + +P +Y Sbjct: 255 VCWSPLLIMMLKMIFQQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVY 308 >4PHU-A nrPDB Length = 491 Score = 69.3 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 43/129 (33%), Gaps = 2/129 (1%) Query: 39 MLAAYMFLLIMLGFPINFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVFGGFTTTLYT 97 + LGFP+N L + H +LR TP LNL +DL + + Sbjct: 20 LSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSAVYALNLGCSDLLLTVSLPLKAVEA 79 Query: 98 SLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGEN-HAIMG 156 G + + C + L L+ RY+ P+ F ++ Sbjct: 80 LASGAWPLPASLCPVFAVAHFAPLYAGGGFLAALSAARYLGAAFPLGYQAFRRPCYSWGV 139 Query: 157 VAFTWVMAL 165 A W + L Sbjct: 140 CAAIWALVL 148 >6M9T-A nrPDB Length = 537 Score = 63.2 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 35/210 (16%), Positives = 75/210 (35%), Gaps = 15/210 (7%) Query: 42 AYMFLLIMLGFPINFLTLYVT---VQHKKLRTPLNYI--LLNLAVADLF-MVFGGFTTTL 95 A+ +++ GF N L + + + ++ + +++ + LA+ DL + + Sbjct: 65 AFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIV 124 Query: 96 YTSLHGYFVFGPT---GCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENH 152 + C G T+ G +L+ +A+ER + + P + Sbjct: 125 VYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTR 184 Query: 153 AIMGVAF-TWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHE---ETNNESFVIYMF 208 A V W+ LA A P++G +Y + C I ++N + + Sbjct: 185 ATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFAS 244 Query: 209 VVHF--IIPLIVIFFCYGQLVFTVKEAAAQ 236 F ++ L V F C + + + Sbjct: 245 AFAFLGLLALTVTFSCNLATIKALVSRGSN 274 >6IIU-A nrPDB Length = 484 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 50/340 (14%), Positives = 97/340 (28%), Gaps = 73/340 (21%) Query: 47 LIMLGFPINFLTLYVTVQHK----KLRTPLNYILLNLAVADLF-MVFGGFTTTLYTSLHG 101 ++G N L L V + R+ L L + D ++ G + Sbjct: 141 FCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALF 200 Query: 102 YFVFGPTGCNLEGFFATLGGEIALWSLV---VLAIERYVVVCKPM-SNFRFGENHAIMGV 157 + GC L F + L L+ +A ERY+ + +P + A V Sbjct: 201 EWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATV 260 Query: 158 AFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLI 217 W ALA PL+G RY + C + + + + + + Sbjct: 261 GLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFL 320 Query: 218 VIFF---CYGQLVFTVKE----------------------------------------AA 234 + + +K+ Sbjct: 321 LNTVSVATLCHVYHGMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVG 380 Query: 235 AQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGP--------- 285 Q E + +E E+ + +++ +CWLP P Sbjct: 381 KDQFEEVEERDSEVEMMAQALGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTE 440 Query: 286 ----IFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTL 321 I++ + + + + +P +YI+ FR ++ L Sbjct: 441 KELLIYLRVATW----NQILDPWVYIL----FRRAVLRRL 472 >2LOT-A nrPDB Length = 64 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 15/29 (51%) Query: 38 SMLAAYMFLLIMLGFPINFLTLYVTVQHK 66 +++ A L+ +LG N L L+ + K Sbjct: 29 ALIPAIYMLVFLLGTTGNGLVLWTVFRKK 57 >4K5Y-A nrPDB Length = 441 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 26/167 (15%), Positives = 55/167 (32%), Gaps = 18/167 (10%) Query: 135 RYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTP 194 R + + + + A M + W + P +V W+ C Sbjct: 265 RVIATFRTGTWDAYDRLRAWMFICIGWGVPF----PIIVAWAIGKLYYDNEKC------- 313 Query: 195 HEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQ--KAEKEVTR 252 + Y++ + L++ F +V + S T Q KA K Sbjct: 314 WAGKRPGVYTDYIYQGPMALVLLINFIFLFNIVRILMTKLRASTTSETIQARKAVKATLV 373 Query: 253 MVIIMVIAFLICWL-----PYAGVAFYIFTHQGSDFGPIFMTIPAFF 294 ++ ++ I +++ ++ + V F F F F+++ A F Sbjct: 374 LLPLLGITYMLAFVNPGEDEVSRVVFIYFNAFLESFQGFFVSVFACF 420 >4WFO-A nrPDB Length = 858 Score = 28.1 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 26/81 (32%), Gaps = 1/81 (1%) Query: 77 LNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERY 136 L+ AV+ + + + L +V C + L A V+A R+ Sbjct: 478 LSAAVSQVVLPAKEGVESTIWLLAKAYVIVNDSCYHQLMSHWLNTHAA-MEPFVIATHRH 536 Query: 137 VVVCKPMSNFRFGENHAIMGV 157 + V P+ M + Sbjct: 537 LSVLHPIYKLLTPHYRNNMNI 557 >6B3J-R nrPDB Length = 491 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 38/295 (12%), Positives = 86/295 (29%), Gaps = 20/295 (6%) Query: 32 AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF 91 + Q L + L F + + + + L NYI LNL + + F Sbjct: 145 SPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVF 204 Query: 92 TTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSL--VVLAIERYVVVCKPMSNFRFG 149 + + ++ L +A Y ++ + + + Sbjct: 205 IKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTL- 263 Query: 150 ENHAIMGVAFTWV----MALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVI 205 A + W+ +++ P L +P G+ D +N ++I Sbjct: 264 --LAFSVFSEQWIFRLYVSIGWGVPLLFV----VPWGIVKYLYEDEGCWTRNSNMNYWLI 317 Query: 206 YMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICW 265 + F I + + F + V + A + + T +I ++ + Sbjct: 318 IRLPILFAIGVNFLIFV-RVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEV-- 374 Query: 266 LPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTT 320 AF + H I + F + ++Y +N + + + Sbjct: 375 ----IFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKS 425 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.317 0.132 0.385 Lambda K H 0.267 0.0404 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,630,964 Number of Sequences: 36641 Number of extensions: 454384 Number of successful extensions: 2099 Number of sequences better than 10.0: 120 Number of HSP's better than 10.0 without gapping: 174 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 1250 Number of HSP's gapped (non-prelim): 356 length of query: 348 length of database: 10,336,785 effective HSP length: 98 effective length of query: 250 effective length of database: 6,745,967 effective search space: 1686491750 effective search space used: 1686491750 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.2 bits) S2: 59 (27.4 bits)