BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P01015 (477 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2WXZ-C nrPDB 922 0.0 2WXX-A nrPDB 804 0.0 5M3Y-A nrPDB 569 e-163 6EE5-A nrPDB 110 1e-24 5INW-A nrPDB 95 8e-20 5HGC-A nrPDB 83 2e-16 4Y40-A nrPDB 82 4e-16 2OL2-A nrPDB 79 6e-15 3NE4-A nrPDB 77 2e-14 4AJT-A nrPDB 77 2e-14 3DY0-A nrPDB 74 1e-13 1IMV-A nrPDB 73 2e-13 4KDS-A nrPDB 71 1e-12 3ZHA-A nrPDB 71 1e-12 4ZK0-A nrPDB 68 8e-12 1JMJ-A nrPDB 68 1e-11 2VDY-A nrPDB 68 1e-11 1QMB-A nrPDB 64 2e-10 6HGE-B nrPDB 63 2e-10 4AJU-A nrPDB 62 4e-10 2V95-A nrPDB 62 5e-10 4DTE-A nrPDB 60 2e-09 1YXA-A nrPDB 57 2e-08 1BY7-A nrPDB 56 3e-08 2OAY-A nrPDB 55 7e-08 4P0F-A nrPDB 54 1e-07 1UHG-A nrPDB 53 3e-07 3F02-A nrPDB 50 3e-06 4EB1-I nrPDB 50 3e-06 1JJO-C nrPDB 49 5e-06 6CJ7-A nrPDB 48 8e-06 1ATT-A nrPDB 48 8e-06 2R9Y-A nrPDB 48 9e-06 4DY0-A nrPDB 47 1e-05 6F02-A nrPDB 47 1e-05 6F4U-A nrPDB 47 1e-05 2XN5-A nrPDB 47 2e-05 3NDA-A nrPDB 44 1e-04 5NCS-A nrPDB 41 9e-04 4GA7-A nrPDB 41 0.001 1C5G-A nrPDB 38 0.010 2PEF-A nrPDB 36 0.037 3LE2-A nrPDB 34 0.15 1SNG-A nrPDB 33 0.18 3PZF-A nrPDB 32 0.84 3STO-A nrPDB 31 1.00 4YH2-A nrPDB 30 2.3 6BQ9-A nrPDB 29 5.4 6C5C-A nrPDB 28 7.6 >2WXZ-C nrPDB Length = 453 Score = 922 bits (2383), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/453 (100%), Positives = 453/453 (100%) Query: 25 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 84 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE Sbjct: 1 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 60 Query: 85 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 144 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 204 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA Sbjct: 121 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 180 Query: 205 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 264 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD Sbjct: 181 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 240 Query: 265 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 324 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR Sbjct: 241 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 300 Query: 325 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 444 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL Sbjct: 361 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 420 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 477 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV Sbjct: 421 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 453 >2WXX-A nrPDB Length = 453 Score = 804 bits (2076), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/453 (86%), Positives = 416/453 (91%) Query: 25 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 84 DRVYIHPFHLLY++KSTCAQLENPSVETLPE TFEPVPIQAKTSPV+EKTL D+LVLA E Sbjct: 1 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 60 Query: 85 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 144 KLE EDR+RAAQVAMI NF+GFRMYKML+EA ASGA+LSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 204 ASQLQ LL VPVKEGDCTSRLDGHKVL AL+AVQGLLVTQGGSSSQTPLLQS VVGLFTA Sbjct: 121 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGLFTA 180 Query: 205 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 264 PG RLK FV+SL FTPA+FPRSLDLSTDPVLA +KINRF++AVTGWKMNLPLEGVSTD Sbjct: 181 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 240 Query: 265 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 324 STL FNTYVHFQG MRGFSQL G+HEFWVDNS SVSVPM+SGTGNFQHWSDAQNNFSVT Sbjct: 241 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 300 Query: 325 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGE TLLLIQP C SDLDRVE L+FQ+D LTWI+NPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGERATLLLIQPHCISDLDRVEALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 444 DLLA+ KL TLLGAEANL +GDTNPRVGEVLNSILLEL+AGEEEQPT S QQPGSPE L Sbjct: 361 DLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 420 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 477 DVTLSSPFLFAIYE+DSG LHFLGRV+NPQ+VV Sbjct: 421 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 453 >5M3Y-A nrPDB Length = 458 Score = 569 bits (1467), Expect = e-163, Method: Compositional matrix adjust. Identities = 289/450 (64%), Positives = 340/450 (75%), Gaps = 3/450 (0%) Query: 25 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 84 DRVYIHPFHL+ +++STC QL + +PTF P PIQAKTSPVDEK L+D+LVL Sbjct: 1 DRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAA 60 Query: 85 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGA-VLSPPALFGTLVSFYLGSLDP 143 KL+ ED+ RAA V M+ANF+GFR+Y M SE GV GA VLSP A+FGTL S YLG+LD Sbjct: 61 KLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDH 120 Query: 144 TASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFT 203 TA +LQ +LGVP K+ CTSRLD HKVL+ALQAVQGLLV QG + SQ LL STVVG+FT Sbjct: 121 TADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFT 180 Query: 204 APGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVST 263 APGL LKQPFV+ L +TP + PRSLD T+ +AA+KI+RF+QAVTGWK L G S Sbjct: 181 APGLHLKQPFVQGLALYTPVVLPRSLDF-TELDVAAEKIDRFMQAVTGWKTGSSLMGASV 239 Query: 264 DSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVT 323 DSTL FNTYVHFQGKM+GFS L EFWVD STSVSVPMLSG G FQHWSD Q+ FSVT Sbjct: 240 DSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDQSTSVSVPMLSGMGTFQHWSDIQDQFSVT 299 Query: 324 RVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNL 383 +VP ES +LLLIQP ASDLD+VE L FQ + L W+K PR I LT+PQL ++GSY+L Sbjct: 300 QVPFTESASLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDL 359 Query: 384 QDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEV 443 QDLLAQA+L +L E NL K+ + RVGEVLNSI EL+A E E PTES QQ PEV Sbjct: 360 QDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADERE-PTESTQQLNKPEV 418 Query: 444 LDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 L+VTL+ PFLFA+Y++ + ALHFLGRV NP Sbjct: 419 LEVTLNRPFLFAVYDQSATALHFLGRVANP 448 >6EE5-A nrPDB Length = 379 Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 102/380 (26%), Positives = 173/380 (45%), Gaps = 38/380 (10%) Query: 104 MGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTS 163 F +Y+ L+++ SP ++ L LG+ T +Q+ LG S Sbjct: 28 FAFSLYRELAKS-SPDKNIFFSPVSISSALAMLSLGAKGDTHTQILEGLGF-------NS 79 Query: 164 RLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPA 223 D H Q Q LL T L T GLF L+L F+E A Sbjct: 80 EADIH------QGFQHLLQTLNRPKG---LQLKTANGLFVDKSLKLLDSFLEDSKKLYQA 130 Query: 224 IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRG-F 282 + + DP A ++IN +V+ T K+ L+ + +D+ L ++F+GK + F Sbjct: 131 ---EAFSVDFDPEEAKKQINDWVEKQTNGKIKDLLKDLDSDTVLVLVNAIYFKGKWKKPF 187 Query: 283 S-QLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCA 341 + T +F VD T+V VPM+S G F ++ D + + V +P + ++L+I P Sbjct: 188 DPENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDDELSCKVLELPYKGNASMLIILPDEG 247 Query: 342 SDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEAN 401 L +E + W+K+ R++ L LP+ +I G+Y+L+++L+ ++ L A+ Sbjct: 248 G-LQHLEQSLTPETLSKWLKSLTRRSVELYLPKFKIEGTYDLKEVLSNLGITDLFSPGAD 306 Query: 402 LGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQ------PGS--PEVLDVTLSSPFL 453 L + + V + ++ +LE+ E+ TE+A P S PE PFL Sbjct: 307 LSGITEEKLYVSKAVHKAVLEVN----EEGTEAAAATFLEAIPMSIPPE---FKADRPFL 359 Query: 454 FAIYERDSGALHFLGRVDNP 473 F I E +G++ F+G+V NP Sbjct: 360 FLIRENKTGSILFMGKVVNP 379 >5INW-A nrPDB Length = 421 Score = 94.7 bits (234), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 98/396 (24%), Positives = 165/396 (41%), Gaps = 28/396 (7%) Query: 24 GDRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLAT 83 G+R Y+ PFHL+ S S A E P E P P+ SP Sbjct: 1 GERPYMQPFHLIPPSLSVQAT-EQPLASN--EAWDYPEPLAPGQSPAASSEEGSSEEKGD 57 Query: 84 EKLEAEDRQRAA----------QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTL 133 E+ D + ++A N +GFR+YK + G A SP ++ L Sbjct: 58 EREPHGDEGKRGRKDKKKSKTQRIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASAL 117 Query: 134 VSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPL 193 G+ T ++L LG L G K +++ L S+ L Sbjct: 118 GVVTAGANGSTRAELDTALGF-------KEFLHGKKKAKSMKYFARLNGALYKRSAGFEL 170 Query: 194 LQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWK 253 + VV F+ GL L + F ++ + RS+D D A + +N +++ VT K Sbjct: 171 MGKNVV--FSKKGLWLYRQFTRTVAHLFKSNV-RSVDFG-DSKNAVELMNAYIEKVTSKK 226 Query: 254 MNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQ--LTGLHEFWVDNSTSVSVPMLSGTGNFQ 311 + V TD++L ++F+G + LT FWV++S S+ VP + Sbjct: 227 FPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPDLTKNVRFWVNSSYSMMVPTMHQRAKLS 286 Query: 312 HWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIK--NPPPRAIR 369 + D + +V ++P ++L+I P DL +VE V Q W+ P ++ Sbjct: 287 YTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEEWLSLLGPSNHYVQ 346 Query: 370 LTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKM 405 L+LP+ +I SY+L+ L+ +S++ A+L ++ Sbjct: 347 LSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRI 382 >5HGC-A nrPDB Length = 380 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 61/248 (24%), Positives = 124/248 (50%), Gaps = 15/248 (6%) Query: 235 PVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRG--FSQLTGLHEFW 292 P A ++IN +++ T K+ ++ + + + ++V+F+G ++ T EF+ Sbjct: 135 PTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEKPFEAEHTEEREFF 194 Query: 293 VDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVF 352 VD T+V VPM+ G F + D + + +V R+ S T L+ P + ++E + Sbjct: 195 VDAETTVKVPMMYQMGRFDFYFDEELSCTVVRLHYNGSATAFLVLP-AKGKMKQLEQTLD 253 Query: 353 QHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANL-GKMGDTNPR 411 + W + R + L P+ I GSY + + L + + + +A+L G G + + Sbjct: 254 KETIQKWSDHLFQRFMNLYFPKFSISGSYEISNTLRKMGIVDVFTNQADLSGITGSPDLK 313 Query: 412 VGEVLNSILLELQAGEEEQPTESAQQPGSPEVLDVT------LSSPFLFAIYERDSGALH 465 V +V++ L++ +E+ TE+A + E++ ++ S PFL I++RD+ + Sbjct: 314 VSKVVHKASLDV----DEKGTEAAAA-TAVEIMPISFPPTIEFSHPFLMLIFDRDTNSTL 368 Query: 466 FLGRVDNP 473 F+G++ NP Sbjct: 369 FIGKIVNP 376 >4Y40-A nrPDB Length = 414 Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 89/397 (22%), Positives = 180/397 (45%), Gaps = 37/397 (9%) Query: 89 EDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQL 148 + R A ++A +GF++ K L+ LSP ++ LG+ D T ++ Sbjct: 40 KQRMAAKELARQNMDLGFKLLKKLA-FYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEI 98 Query: 149 QVLLGVPVKEGDCTSRLDG-HKVLTAL-QAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPG 206 + G ++ +G H ++ L Q Q L ++ G + LF Sbjct: 99 KQ--GFNFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNT-------------LFIDQR 143 Query: 207 LRLKQPFVESLGPFTPA--IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 264 L+ ++ F+E F A I +L +A ++IN F+ T K+N +E + Sbjct: 144 LQPQRKFLEDAKNFYSAETILTNFQNLE----MAQKQINDFISQKTHGKINNLIENIDPG 199 Query: 265 STLFFNTYVHFQGKMRG-FS-QLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSV 322 + + Y+ F+ + + F +T +F+++ ++SV VPM+ +G +Q D + + ++ Sbjct: 200 TVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTI 259 Query: 323 TRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYN 382 +P +++T + I P L +E + F W R + +++P+L + G+++ Sbjct: 260 LEIPYQKNITAIFILPD-EGKLKHLEKGLQVDTFSRWKTLLSRRVVCVSVPRLHMTGTFD 318 Query: 383 LQDLLAQAKLSTLLGAEANLGKMG-DTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSP 441 L+ L+ +S + +L K+ + +VGE ++ L++ +E+ TE A G+ Sbjct: 319 LKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKM----DERGTEGAAGTGAQ 374 Query: 442 EV-----LDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + L V + P+L IY ++ FLG++ NP Sbjct: 375 TLPMETPLCVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411 >2OL2-A nrPDB Length = 395 Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 73/286 (25%), Positives = 128/286 (44%), Gaps = 23/286 (8%) Query: 200 GLFTAPGLRLKQPFVESLGPFTPA-IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL 258 LFT + L+ FV ++ A FP + D A ++IN +V T K+ L Sbjct: 121 ALFTDLVVDLQDTFVSAMKTLYLADTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLL 177 Query: 259 EGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHE--FWVDNSTSVSVPMLSGTGNFQHWSDA 316 + + +++ + Y+ F+ K G E F+V + T V VPM+S + + D Sbjct: 178 KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDR 237 Query: 317 QNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLE 376 + V VP + T L I P + +VE + + W+K R + L LP+ Sbjct: 238 NLSCRVVGVPYQGNATALFILP-SEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFS 296 Query: 377 IRGSYNLQDLLAQAKLSTLLGAEANL-GKMGDTNPRVGEVLNSILLELQAGEEEQPTESA 435 I GSY L+ +L +S + + A+L G +N +V E+++ ++E+ +E T +A Sbjct: 297 IEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV----DESGTRAA 352 Query: 436 QQPGSPEVL--------DVTLSSPFLFAIYERDSGALHFLGRVDNP 473 G+ + + PFL I + + + FLG+V+ P Sbjct: 353 AATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLGKVNRP 395 >3NE4-A nrPDB Length = 424 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 85/314 (27%), Positives = 152/314 (48%), Gaps = 31/314 (9%) Query: 175 QAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGP-FTPAIFPRSLDLST 233 + Q LL T SQ L +T GLF + GL+L F+E + + F + Sbjct: 124 EGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG--- 178 Query: 234 DPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM-RGFS-QLTGLHEF 291 D A ++IN +V+ T K+ ++ + D+ Y+ F+GK R F + T +F Sbjct: 179 DTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 238 Query: 292 WVDNSTSVSVPMLSGTG--NFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEV 349 VD T+V VPM+ G N QH + + + LG + + + + L +E Sbjct: 239 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY-LGNATAIFFLPDE--GKLQHLEN 295 Query: 350 LVFQHDFLT-WIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDT 408 + HD +T +++N R+ L LP+L I G+Y+L+ +L Q ++ + A+L + + Sbjct: 296 EL-THDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEE 354 Query: 409 NP-RVGEVLNSILLELQAGEEEQPTESAQQ------PGS--PEVLDVTLSSPFLFAIYER 459 P ++ + ++ +L + +E+ TE+A P S PE V + PF+F + E+ Sbjct: 355 APLKLSKAVHKAVLTI----DEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQ 407 Query: 460 DSGALHFLGRVDNP 473 ++ + F+G+V NP Sbjct: 408 NTKSPLFMGKVVNP 421 >4AJT-A nrPDB Length = 427 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/242 (26%), Positives = 112/242 (46%), Gaps = 15/242 (6%) Query: 242 INRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGK-MRGFS-QLTGLHEFWVDNSTSV 299 IN + T K+ + ++ ++ L YV F+GK + F T F +D ++ Sbjct: 188 INHCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPFDPSFTEADTFHLDKYRAI 247 Query: 300 SVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTW 359 VPM+ GNF D + + ++P + T+L++ + D +E + TW Sbjct: 248 KVPMMYREGNFTSTFDKKFRCHILKLPYQGNATMLVVLMEKTGDYLALEDYLTVDLVETW 307 Query: 360 IKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDT--NPRVGEVLN 417 ++N R + + P+ ++ Y + +LL Q + L A+L ++ N +V VL Sbjct: 308 LQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIRRLFSTSADLSELSAMARNLQVSRVLQ 367 Query: 418 SILLELQAGEEEQPTESAQQPGSPEVLD------VTLSSPFLFAIYERDSGALHFLGRVD 471 +LE+ +E+ TE+ S E++ + ++ PF F IYE S L FLGRV Sbjct: 368 QSVLEV----DERGTEAVSGTLS-EIIAYSMPPAIKVNRPFHFIIYEEMSRMLLFLGRVV 422 Query: 472 NP 473 NP Sbjct: 423 NP 424 >3DY0-A nrPDB Length = 336 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/245 (26%), Positives = 112/245 (45%), Gaps = 12/245 (4%) Query: 200 GLFTAPGLRLKQPFVESLGPFTPA-IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL 258 LFT + L+ FV ++ A FP + D A ++IN +V T K+ L Sbjct: 96 ALFTDLVVDLQDTFVSAMKTLYLADTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLL 152 Query: 259 EGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHE--FWVDNSTSVSVPMLSGTGNFQHWSDA 316 + + +++ + Y+ F+ K G E F+V + T V VPM+S + + D Sbjct: 153 KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDR 212 Query: 317 QNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLE 376 + V VP + T L I P + +VE + + W+K R + L LP+ Sbjct: 213 NLSCRVVGVPYQGNATALFILP-SEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFS 271 Query: 377 IRGSYNLQDLLAQAKLSTLLGAEANL-GKMGDTNPRVGEVLNSILLELQAGEEEQPTESA 435 I GSY L+ +L +S + + A+L G +N +V E+++ ++E+ +E T +A Sbjct: 272 IEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV----DESGTRAA 327 Query: 436 QQPGS 440 G+ Sbjct: 328 AATGT 332 >1IMV-A nrPDB Length = 398 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 96/392 (24%), Positives = 179/392 (45%), Gaps = 46/392 (11%) Query: 98 AMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVK 157 A ++NF G+ +Y++ S + + +LSP ++ L + LG+ + T S + L Sbjct: 36 AAVSNF-GYDLYRVRS-SMSPTTNVLLSPLSVATALSALSLGADERTESIIHRALYY--- 90 Query: 158 EGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESL 217 D S D H L + + Q L+S +F LR+K FV Sbjct: 91 --DLISSPDIHGTYKEL--LDTVTAPQKN-------LKSASRIVFEK-KLRIKSSFV--- 135 Query: 218 GPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQG 277 P + R L+ +P L Q+IN +VQA K+ + + + ++ HF+G Sbjct: 136 APLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKG 195 Query: 278 K--MRGFSQLTGLHEFWVDNSTSVSVPMLSG-TGNFQHWSDAQNNFSVTRVPLGESVTLL 334 + + S+ T L +F++D +V VPM+S ++ D+ + + ++PL S++++ Sbjct: 196 QWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSII 255 Query: 335 LIQP-QCASDLDRVEVLV---FQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQA 390 P + +L +E + F HD +K +A+ LT+P+L++ + L + Sbjct: 256 FFLPLKVTQNLTLIEESLTSEFIHDIDRELKTV--QAV-LTVPKLKLSYEGEVTKSLQEM 312 Query: 391 KLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEV------- 443 KL +L + D + G+ + +E +AG E + P SP + Sbjct: 313 KLQSLFDSP-------DFSKITGKPIKLTQVEHRAGFEWNEDGAGTTP-SPGLQPAHLTF 364 Query: 444 -LDVTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 LD L+ PF+F + + D+GAL F+G++ +P+ Sbjct: 365 PLDYHLNQPFIFVLRDTDTGALLFIGKILDPR 396 >4KDS-A nrPDB Length = 386 Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 85/329 (25%), Positives = 145/329 (44%), Gaps = 23/329 (6%) Query: 167 GHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVV---------GLFTAPGLRLKQPFVESL 217 G L L A G + + G + Q LLQ + G+ + L++ F L Sbjct: 58 GGNTLKTLNAKLGFSLQERGMARQQRLLQRDISSEEGVELASGVMVERKMALEKGFRRGL 117 Query: 218 GPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKM-NLPLEGVSTDST-LFFNTYVHF 275 G A P LD S P A IN +V T + + G TD T + +HF Sbjct: 118 GKAFQAS-PHQLDFSR-PDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALHF 175 Query: 276 QG--KMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQ---NNFSVTRVPL-GE 329 QG K+ ++T F N +SV VPM+ T F++ ++ V VP GE Sbjct: 176 QGLWKVPFDPKMTEERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPYEGE 235 Query: 330 SVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLA 388 S+++LL+ P + + + + + W + +L LP+ + L+ +L Sbjct: 236 SLSMLLVSPFEPETPVSSLSSELTTQRLQQWRQEMRSVKRQLVLPRFTLDSEVELKSILI 295 Query: 389 QAKLSTLLG-AEANLGKMGDTNPR-VGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLD 445 Q L + A+A+ ++ P V +VL + +E+ + G + +A V + Sbjct: 296 QMGLGDMFNLAKADFTRITTEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMAVEE 355 Query: 446 VTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 +T++ PFLF I+ + +GA+ F+G+V+ PQ Sbjct: 356 ITMNRPFLFLIHHKSTGAVLFMGQVNQPQ 384 >3ZHA-A nrPDB Length = 392 Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 86/391 (21%), Positives = 168/391 (42%), Gaps = 28/391 (7%) Query: 93 RAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLL 152 +AA +A + + F +Y+ +++ + V +LSP + +L LG TASQ + +L Sbjct: 5 KAATLAERSAGLAFSLYQAMAKDQAV-ENILLSPVVVASSLGLVSLGGKATTASQAKAVL 63 Query: 153 GVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQP 212 +L +V L G L+ +S+ + L+ + + Sbjct: 64 --------SAEQLRDEEVHAGL----GELLRSLSNSTARNVTWKLGSRLYGPSSVSFAED 111 Query: 213 FVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVS-TDSTLFFNT 271 FV S + ++ D A Q IN + T K+ + V TD L N Sbjct: 112 FVRSSKQHYNCEHSK-INFR-DKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNA 169 Query: 272 YV---HFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLG 328 H+ K ++ F V S +V V M+ TG + ++ D + + +PL Sbjct: 170 MFFKPHWDEKFH--HKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQIVEMPLA 227 Query: 329 ESVT-LLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLL 387 ++ L+++ P L+R+E L+ + W+ +A+ ++LP+ + +++LQ L Sbjct: 228 HKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHL 287 Query: 388 AQAKLSTLLGA-EANLGKM-GDTNPRVGEVLNSILLEL--QAGEEEQPTESAQQPGSPEV 443 A L+ + +A+L +M G + + V ++ E + +Q ++ SP++ Sbjct: 288 AGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKL 347 Query: 444 LDVTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 PF+F + + SG+L F+GR+ P+ Sbjct: 348 F--YADHPFIFLVRDTQSGSLLFIGRLVRPK 376 >4ZK0-A nrPDB Length = 390 Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 86/386 (22%), Positives = 166/386 (43%), Gaps = 27/386 (6%) Query: 108 MYKMLSEARGVASGAVL-SPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLD 166 M+ + + R + SP ++ L LG+ D TA Q++ +L + T + Sbjct: 12 MFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAA 71 Query: 167 GHKVLTA---LQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPA 223 + V + Q LL S+ L LF Q +++++ F Sbjct: 72 TYHVDRSGNVHHQFQKLLTEFNKSTDAYEL--KIANKLFGEKTYLFLQEYLDAIKKFYQT 129 Query: 224 IFPRSLDLSTDPVLAAQKINRFVQAVTGWKM-NLPLEG-VSTDSTLFFNTYVHFQGKM-R 280 S+D + P + +KIN +V++ T K+ NL EG + +++TL ++F+G+ + Sbjct: 130 SV-ESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEK 188 Query: 281 GFSQL-TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GESVTLLLIQP 338 F++ T +FW + +T S+ M+ +F S V +P G+ ++++++ P Sbjct: 189 KFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLP 248 Query: 339 QCASDLDRVEVLVFQHDFLTW--IKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLL 396 L ++E + + W ++N + L LP+ ++ SY+L+D L + + Sbjct: 249 NEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIF 308 Query: 397 GAEANLGKMGDTNPRVGEVLNSILLE---------LQAGEEEQPTESAQQPGSPEVLDVT 447 +A+L M T R G VL+ +L + +A P S + Sbjct: 309 NGDADLSGM--TGSR-GLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNE-EFH 364 Query: 448 LSSPFLFAIYERDSGALHFLGRVDNP 473 + PFLF I + + ++ F GR +P Sbjct: 365 CNHPFLFFIRQNKTNSILFYGRFSSP 390 >1JMJ-A nrPDB Length = 480 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 56/245 (22%), Positives = 107/245 (43%), Gaps = 6/245 (2%) Query: 233 TDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGK-MRGF-SQLTGLHE 290 +DP + K N + +T + LE + + + ++F+G + F ++T H Sbjct: 235 SDPAFIS-KTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTHNHN 293 Query: 291 FWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVL 350 F ++ V V M+ GNF +D + + + ++ +++L++ P S + +E Sbjct: 294 FRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQ 353 Query: 351 VFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNP 410 + W K+ R + LP+ ++ +YNL + L + L N+ + D Sbjct: 354 LTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQRI 413 Query: 411 RVG--EVLNSILLELQAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLG 468 + + +I + + + T P S +V T+ PFLF IYE + L F+G Sbjct: 414 AIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV-RFTVDRPFLFLIYEHRTSCLLFMG 472 Query: 469 RVDNP 473 RV NP Sbjct: 473 RVANP 477 >2VDY-A nrPDB Length = 373 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 87/379 (22%), Positives = 158/379 (41%), Gaps = 31/379 (8%) Query: 105 GFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSR 164 F +YK L A +SP ++ L LG+ T +QL LG + E T Sbjct: 15 AFSLYKHLV-ALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEI 73 Query: 165 LDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPA- 223 G + L L A S T L + LF L L + F + + + Sbjct: 74 HQGFQHLHQLFA-----------KSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESE 122 Query: 224 IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFS 283 + + D A+++IN +V+ T K+ G+ + + L Y+ F+G Sbjct: 123 VLAMNFQ---DWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPF 179 Query: 284 QLTGLHE--FWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCA 341 L E F+VD +T V VPM+ + + D++ + ++ + T+ I P Sbjct: 180 DLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPD-K 238 Query: 342 SDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEAN 401 ++ V + + W + L +P++ I G Y+L D+L + ++ L +AN Sbjct: 239 GKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQAN 298 Query: 402 LGKMG-DTNPRVGEVLNSILLELQAGEEEQPTESAQQ------PGSPEVLDVTLSSPFLF 454 ++ D + +V++ +L+L E+ TE+A P S ++ + + PF+ Sbjct: 299 FSRITQDAQLKSSKVVHKAVLQLN----EEGTEAAGAMFLEAIPRSKPII-LRFNQPFII 353 Query: 455 AIYERDSGALHFLGRVDNP 473 I++ + + FL RV NP Sbjct: 354 MIFDHFTWSSLFLARVMNP 372 >1QMB-A nrPDB Length = 326 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 70/267 (26%), Positives = 125/267 (46%), Gaps = 19/267 (7%) Query: 175 QAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGP-FTPAIFPRSLDLST 233 + Q LL T SQ L +T GLF + GL+L F+E + + F + Sbjct: 69 EGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG--- 123 Query: 234 DPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM-RGFS-QLTGLHEF 291 D A ++IN +V+ T K+ ++ + D+ Y+ F+GK R F + T +F Sbjct: 124 DTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 183 Query: 292 WVDNSTSVSVPMLSGTG--NFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEV 349 VD T+V VPM+ G N QH + + + LG + + + + L +E Sbjct: 184 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY-LGNATAIFFLPDE--GKLQHLEN 240 Query: 350 LVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTN 409 + HD +T R+ L LP+L I G+Y+L+ +L Q ++ + A+L + + Sbjct: 241 EL-THDIITKFLENDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEA 299 Query: 410 P-RVGEVLNSILLELQAGEEEQPTESA 435 P ++ + ++ +L + +E+ TE+A Sbjct: 300 PLKLSKAVHKAVLTI----DEKGTEAA 322 >6HGE-B nrPDB Length = 409 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 99/424 (23%), Positives = 175/424 (41%), Gaps = 42/424 (9%) Query: 66 KTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVA---MIANF-MGFRMYKMLSEARGVASG 121 + SP+DE E L E++ R V AN F +YK L + Sbjct: 11 QNSPLDE-----------ENLTQENQDRGTHVDRGLASANVDFAFSLYKQLV-LKAPDKN 58 Query: 122 AVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLL 181 + SP ++ L LG+ + T +++ L + E TS + H Q+ Q LL Sbjct: 59 VIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTE---TSEAEIH------QSFQHLL 109 Query: 182 VTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGP-FTPAIFPRSLDLSTDPVLAAQ 240 T SS + L S +F L L F E + F D A + Sbjct: 110 RTLNQSSDELQL--SMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQ---DSAAAKK 164 Query: 241 KINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGK--MRGFSQLTGLHEFWVDNSTS 298 IN +V+ T K+ ++ + + + + Y+ F+ K M Q T F++ Sbjct: 165 LINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKW 224 Query: 299 VSVPMLSGTG-NFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFL 357 V VPM+S ++ D + + +V ++ + + L I P ++ VE ++ + Sbjct: 225 VMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPD-QDKMEEVEAMLSRETLN 283 Query: 358 TWIKNPPPRAI-RLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANL-GKMGDTNPRVGEV 415 W + R I L LP+ I YNL D+L Q + ++A+L G G N V +V Sbjct: 284 RWGDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQV 343 Query: 416 LNSILLEL-QAGEEEQPTESAQQPGSPEVLD----VTLSSPFLFAIYERDSGALHFLGRV 470 ++ +L++ + G E + + +++ V + PFL I + + ++ F+ +V Sbjct: 344 VHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVDHFTWSIFFMSKV 403 Query: 471 DNPQ 474 NP+ Sbjct: 404 TNPK 407 >4AJU-A nrPDB Length = 387 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 76/348 (21%), Positives = 145/348 (41%), Gaps = 33/348 (9%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGV- 154 Q+A + GF + + +S V SP + + LG+ PT +Q++ L + Sbjct: 53 QLAKETSNFGFSLLRKISMRHD--GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 110 Query: 155 ---PVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQ 211 P K G S G + + GL TQG + F +K+ Sbjct: 111 ALKPTKPGLLPSLFKGLRETLSRNLELGL--TQGSFA-------------FIHKDFDVKE 155 Query: 212 PFVE-SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFN 270 F S F P + ++ A + +N ++ T K+ + ++ ++ L Sbjct: 156 TFFNLSKRYFDTECVPMNFRNASQ---AKRLMNHYINKETRGKIPKLFDEINPETKLILV 212 Query: 271 TYVHFQGK-MRGFSQL-TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLG 328 Y+ F+GK + F + T + F +D ++ VPM+ G G F D V ++P Sbjct: 213 DYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQ 272 Query: 329 ESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLA 388 + T+L++ + D +E + TW++N R + + P+ ++ Y + +LL Sbjct: 273 GNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLR 332 Query: 389 QAKLSTLLGAEANLGKMGDT--NPRVGEVLNSILLELQAGEEEQPTES 434 Q + + A+L ++ T N +V VL ++E+ +E+ TE+ Sbjct: 333 QMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEV----DERGTEA 376 >2V95-A nrPDB Length = 371 Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 83/378 (21%), Positives = 163/378 (43%), Gaps = 33/378 (8%) Query: 105 GFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVL--LGVPVKEGDCT 162 F +Y+ L A ++SP ++ L LGS +Q Q L LG + E T Sbjct: 17 AFNLYQRLV-ALNPDKNTLISPVSISMALAMVSLGS-----AQTQSLQSLGFNLTE---T 67 Query: 163 SRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTP 222 S + H+ + Q + LL S T L + +F L+LK F+ + + Sbjct: 68 SEAEIHQ---SFQYLNYLL-----KQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYE 119 Query: 223 AIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGF 282 + ++D D A+Q+IN+ V+ T K+ + + ++ Y+ +RG Sbjct: 120 SE-ALAIDFE-DWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIF----LRGI 173 Query: 283 SQL------TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLI 336 +L T +F+V+ +++V VPM+ +G+ ++ D+ + ++ + T I Sbjct: 174 WELPFSPENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAFFI 233 Query: 337 QPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLL 396 P +D V + + W K PR + L +P+ + +Y+L+D+L + LL Sbjct: 234 LPDQGQ-MDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSMSDTYDLKDVLEDLNIKDLL 292 Query: 397 GAEANLGKMGDTNPRVGEVLNSILLELQAGEE-EQPTESAQQPGSPEVLDVTLSSPFLFA 455 +++ P +++ +L+L G T A E LD+ + PF+ Sbjct: 293 TNQSDFSGNTKDVPLTLTMVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLDIKFNKPFILL 352 Query: 456 IYERDSGALHFLGRVDNP 473 ++++ + + + +V NP Sbjct: 353 LFDKFTWSSLMMSQVVNP 370 >4DTE-A nrPDB Length = 374 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 71/288 (24%), Positives = 129/288 (44%), Gaps = 14/288 (4%) Query: 200 GLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMN--LP 257 G+ + L++ F SL ++ P +D S P +A Q IN + T ++ LP Sbjct: 88 GVMVDRKIILEKVFRRSLSKAFQSV-PHQIDFS-QPEMARQVINSWTSDHTDGMISEFLP 145 Query: 258 LEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHE--FWVDNSTSVSVPMLSGTGNFQHW-- 313 +S + L F +HF G + E F N ++VSVPM++ T F + Sbjct: 146 SGVLSELTRLVFLNALHFHGVWKTPFDPRNTREQLFHTVNGSAVSVPMMTTTQKFNYGEF 205 Query: 314 -SDAQNNFSVTRVPL-GESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRL 370 S ++ V +P GES+++LL+ P + L + + W + + +L Sbjct: 206 VSKDGVDYDVIEMPYEGESISMLLVTPFEKDVPLSALNKELSSSRIHQWRQEMRKISKQL 265 Query: 371 TLPQLEIRGSYNLQDLLAQAKLSTLLG-AEANLGKMGDTNPR-VGEVLNSILLEL-QAGE 427 ++P+ + +L+ L++ L + + A+ ++ P V +VL + LE+ + G Sbjct: 266 SIPRFSMDTEIDLKSTLSRMGLGDIFSQSRADFSRITTEEPLCVSKVLQRVKLEVNEEGT 325 Query: 428 EEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQN 475 + +A V ++TL PF F I + +GAL F G++ PQ Sbjct: 326 KGSSATAAVIYSRMAVEEITLDRPFFFLIQHKPTGALLFSGQLTQPQE 373 >1YXA-A nrPDB Length = 398 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 57/249 (22%), Positives = 114/249 (45%), Gaps = 10/249 (4%) Query: 235 PVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRG-FSQL-TGLHEFW 292 P A + IN +V+ T + + + + + Y++F+ K + F L T EF+ Sbjct: 151 PRQAKKLINDYVRKQTQGMIKELVSDLDKRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFY 210 Query: 293 VDNSTSVSVPMLSGTG-NFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLV 351 V VPM+S ++ D + + +V + + + L I P + +VE + Sbjct: 211 CGKRRPVIVPMMSMEDLTTPYFRDEELSCTVVELKYTGNASALFILPDQGR-MQQVEASL 269 Query: 352 FQHDFLTWIKNPPPRAI-RLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKM-GDTN 409 W + PR I L LP+ I Y+L+D+L++ + + +A+L + G + Sbjct: 270 QPETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVFSTQADLSAITGTKD 329 Query: 410 PRVGEVLNSILLELQAGEEEQPTESAQQ--PGSPEV--LDVTLSSPFLFAIYERDSGALH 465 RV +V++ +L++ E + + P S ++ L V + PFL I++ ++ Sbjct: 330 LRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTVYFNRPFLIMIFDTETEIAP 389 Query: 466 FLGRVDNPQ 474 F+ ++ NP+ Sbjct: 390 FIAKIANPK 398 >1BY7-A nrPDB Length = 382 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 82/374 (21%), Positives = 157/374 (41%), Gaps = 45/374 (12%) Query: 124 LSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVT 183 LSP ++ T+ Y+GS T Q+ +L + + D K+ ++ +++ + Sbjct: 30 LSPWSISSTMAMVYMGSRGSTEDQMAKVLQF----NEVGAAAD--KIHSSFRSLSSAI-- 81 Query: 184 QGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKIN 243 +S+ LL+S V LF ++ ++ + + P+++D A +KIN Sbjct: 82 --NASTGNYLLES-VNKLFGEKSASFREEYIRLCQKYYSSE-PQAVDFLECAEEARKKIN 137 Query: 244 RFVQAVTGWKM-NLPLEG-VSTDSTLFFNTYVHFQGKMRG--FSQLTGLHEFWVDNSTSV 299 +V+ T K+ NL EG V D+ + V+F+GK + +L GL+ F V+++ Sbjct: 138 SWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRT 197 Query: 300 SVPM--LSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASD----LDRVEVLVFQ 353 V M L N + D + + +P V++ L+ P +D L+ +E + Sbjct: 198 PVQMMYLREKLNIGYIEDLKAQ--ILELPYAGDVSMFLLLPDEIADVSTGLELLESEITY 255 Query: 354 HDFLTWIKNPP--PRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLG-AEANLGKMGDTNP 410 W + + +PQ ++ Y L+ +L + AN M + N Sbjct: 256 DKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERND 315 Query: 411 R-VGEVLNSILLELQAGEEEQPTESAQQPGS----------PEVLDVTLSSPFLFAIYER 459 + EV + ++++ E+ TE+A G P+ + PFLF I + Sbjct: 316 LFLSEVFHQAMVDVN----EEGTEAAAGTGGVMTGRTGHGGPQFV---ADHPFLFLIMHK 368 Query: 460 DSGALHFLGRVDNP 473 + + F GR +P Sbjct: 369 ITNCILFFGRFSSP 382 >2OAY-A nrPDB Length = 390 Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 86/381 (22%), Positives = 165/381 (43%), Gaps = 42/381 (11%) Query: 105 GFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSR 164 ++Y S + V + SP ++ L LG+ + T + L+ +L P K+ C Sbjct: 40 SLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP-KDFTCVH- 97 Query: 165 LDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAI 224 QA++G T+G +S V +F +P L ++ FV + + Sbjct: 98 ----------QALKG-FTTKGVTS---------VSQIFHSPDLAIRDTFVNASRTLYSSS 137 Query: 225 FPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMR-GFS 283 PR L ++D L + IN +V T K++ L+ + +D+ L ++ K + F Sbjct: 138 -PRVLSNNSDANL--ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFD 194 Query: 284 -QLTGLHEFWVDNSTSVSVPMLSGTGN-FQHWSDAQNNFSVTRVPLGESVTLLLIQPQ-C 340 + T + F NS + VPM++ H+ D V ++ L +++L+++ PQ Sbjct: 195 PKKTRMEPFHFKNSV-IKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNL 253 Query: 341 ASDLDRVEVLVFQHDFLTWIKNPPPRAIR---LTLPQLEIRGSYNLQDLLAQAKLSTLLG 397 L+ +E + F ++ + LTLP++++ S QD+L+ + Sbjct: 254 KHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTS---QDMLSIMEKLEFFD 310 Query: 398 AEANLGKMG---DTNPRVGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLDVTLSSPFL 453 +L G D + +V + + +LEL + G E + + V +V PFL Sbjct: 311 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEV--QQPFL 368 Query: 454 FAIYERDSGALHFLGRVDNPQ 474 F ++++ F+GRV +P+ Sbjct: 369 FMLWDQQHKFPVFMGRVYDPR 389 >4P0F-A nrPDB Length = 393 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 75/325 (23%), Positives = 142/325 (43%), Gaps = 31/325 (9%) Query: 123 VLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLV 182 V SP ++ LG+ + TA+QL LG+ + + + H+VL A Q Q L + Sbjct: 35 VFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAH-SFHQVLAAYQDSQILRI 93 Query: 183 TQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGP-FTPAIFPRSLDLSTDPVLAAQK 241 +F G +L+Q F + L F A +S+D S + V AA Sbjct: 94 ANK---------------IFVMDGYQLRQEFDQLLSKQFLSA--AQSVDFSKN-VQAAAT 135 Query: 242 INRFVQAVTGWKMN--LPLEGVSTDSTLFFNTYVHFQG--KMRGFSQLTGLHEFWVDNST 297 IN +V+ T + +P + ++++S L +HF+G + + LT F +D Sbjct: 136 INNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGER 195 Query: 298 SVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGES-VTLLLIQPQCASDLDRVEVLVFQHDF 356 +V VPM+S F++ + +P +S +++L++ P + L +E + Sbjct: 196 TVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTL 255 Query: 357 LTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDT-NP-RVGE 414 ++ + L LP+ + L ++ + +S + +A GKM + P +V Sbjct: 256 SQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSA 315 Query: 415 VLNSILLELQAGEEEQPTESAQQPG 439 +++ +E+ E+ TE+A G Sbjct: 316 IIHKAFIEVN----EEGTEAAAATG 336 >1UHG-A nrPDB Length = 385 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 42/188 (22%), Positives = 84/188 (44%), Gaps = 5/188 (2%) Query: 291 FWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGE-SVTLLLIQPQCASDLDRVEV 349 F V S V M+ G F+ S A + +P ++++L++ P S L+++E Sbjct: 198 FRVTEQESKPVQMMYQIGLFRVASMASEKMKILELPFASGTMSMLVLLPDEVSGLEQLES 257 Query: 350 LVFQHDFLTWIKNP--PPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGD 407 ++ W + R I++ LP++++ YNL +L ++ + + ANL + Sbjct: 258 IINFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNLTSVLMAMGITDVFSSSANLSGISS 317 Query: 408 TNP-RVGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALH 465 ++ + +++ E+ +AG E + A + + PFLF I + A+ Sbjct: 318 AESLKISQAVHAAHAEINEAGREVVGSAEAGVDAASVSEEFRADHPFLFCIKHIATNAVL 377 Query: 466 FLGRVDNP 473 F GR +P Sbjct: 378 FFGRCVSP 385 >3F02-A nrPDB Length = 359 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 23/238 (9%) Query: 187 SSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFV 246 ++ ++ + LF G + + F++ + + A +D S + V A IN++V Sbjct: 95 TAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNH-VDFSQN-VAVANYINKWV 152 Query: 247 QAVTGWKMNLPLEGVS-----TDSTLFFNTYVHFQGKMRGFSQL----TGLHEFWVDNST 297 + T NL + VS + L V+F+G + SQ T F D+ + Sbjct: 153 ENNTN---NLVKDLVSPRDFDAATYLALINAVYFKGNWK--SQFRPENTRTFSFTKDDES 207 Query: 298 SVSVPMLSGTGNFQH--WSDAQNN----FSVTRVPL-GESVTLLLIQPQCASDLDRVEVL 350 V +PM+ G F + +SD N + V +P G+ ++++L+ + L +E L Sbjct: 208 EVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPL 267 Query: 351 VFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDT 408 V W + + + + LP+ + +L+D+L ++ + +ANL + D Sbjct: 268 VKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDN 325 >4EB1-I nrPDB Length = 440 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 77/387 (19%), Positives = 153/387 (39%), Gaps = 32/387 (8%) Query: 108 MYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDG 167 Y+ L++++ LSP ++ LG+ + T QL + V + D S Sbjct: 62 FYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQL-----MEVFKFDTISEKTS 116 Query: 168 HKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPR 227 ++ + L + +S+ L+ + LF L + + + + + Sbjct: 117 DQIHFFFAKLNCRLYRKANKASK--LVSAN--RLFGDKSLTFNETY-QDISELVYGAKLQ 171 Query: 228 SLDLSTDPVLAAQKINRFVQAVTGWKMN--LPLEGVS--------TDSTLFFNTYVHFQG 277 LD + + IN++V T ++ +P E ++ T + L ++F+G Sbjct: 172 PLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINVLVLVNTRTSTVLVLVNTIYFKG 231 Query: 278 --KMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GESVTLL 334 K + + T F+ + S S M+ G F++ A+ V +P G+ +T++ Sbjct: 232 LWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGT-QVLELPFKGDDITMV 290 Query: 335 LIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLST 394 LI P+ L +VE + W+ + + +P+ I ++L++ L L Sbjct: 291 LILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVD 350 Query: 395 LLGAEAN----LGKMGDTNPRVGEVLNSILLEL-QAGEEEQPTESAQQPG---SPEVLDV 446 L E + + G + V + + LE+ + G E + + G +P + Sbjct: 351 LFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTF 410 Query: 447 TLSSPFLFAIYERDSGALHFLGRVDNP 473 + PFL I E + F+GRV NP Sbjct: 411 KANRPFLVFIREVPLNTIIFMGRVANP 437 >1JJO-C nrPDB Length = 261 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 51/220 (23%), Positives = 95/220 (43%), Gaps = 17/220 (7%) Query: 201 LFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTG--WKMNLPL 258 LF G + + F++ L + A +D S + V A IN++V+ T K + Sbjct: 12 LFVQNGFHVNEEFLQMLKMYFNAEVNH-VDFSQN-VAVANSINKWVENYTNSLLKDLVSP 69 Query: 259 EGVSTDSTLFFNTYVHFQGKMRGFSQL----TGLHEFWVDNSTSVSVPMLSGTGNFQH-- 312 E + L V+F+G + SQ T F D+ + V +PM+ G F + Sbjct: 70 EDFDGVTNLALINAVYFKGNWK--SQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGE 127 Query: 313 WSDAQNN----FSVTRVPL-GESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRA 367 +SD N + V +P G+ ++++L + L +E L+ W + + Sbjct: 128 FSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQK 187 Query: 368 IRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGD 407 + + LP+ + +L+D+L ++ + +ANL M D Sbjct: 188 VEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSD 227 >6CJ7-A nrPDB Length = 390 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 56/251 (22%), Positives = 115/251 (45%), Gaps = 13/251 (5%) Query: 235 PVLAAQKINRFVQAVTGWKMN--LPLEGVSTDSTLFFNTYVHFQG--KMRGFSQLTGLHE 290 P LAAQ IN ++ + T K++ + + +S ++ + V+F+G ++ Q T Sbjct: 131 PALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMVNAVYFKGLWEIPFREQATQKRN 190 Query: 291 FWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLG-ESVTLLLIQPQCASDLDRVEV 349 F ++ + F+ + V +P +L+++ P +S++D + Sbjct: 191 FTLNGGEKKVASFMQTRRYFKAGTHKPAMAKVVVLPFEYNEYSLIVVLPLKSSNVDALLS 250 Query: 350 LVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEA---NLGKMG 406 + D +++ + PP+ + L LP+ I+ NL+ +L + +S++ +A NLG G Sbjct: 251 SLSMEDVASFL-DLPPKDVALELPKFSIKADINLEPVLNKMGVSSIFTQQAELYNLGSHG 309 Query: 407 DTNPRVGEVLNSILLEL--QAGEEEQPTESAQQPGSPE--VLDVTLSSPFLFAIYERDSG 462 +P+V L+S +L + + G T A S + L + PFL +++ S Sbjct: 310 SLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYDEPSLYFRANKPFLAILWDNRSS 369 Query: 463 ALHFLGRVDNP 473 F+ R+ +P Sbjct: 370 IPLFMARIMDP 380 >1ATT-A nrPDB Length = 429 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 75/405 (18%), Positives = 165/405 (40%), Gaps = 24/405 (5%) Query: 82 ATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSL 141 + +K+ +R +++ + Y+ L++++ LSP ++ LG+ Sbjct: 33 SEQKIPGATNRRVWELSKANSHFATAFYQHLADSKNNNDNIFLSPLSISTAFAMTKLGAC 92 Query: 142 DPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGL 201 + T +QL + V + D S ++ + L + SS+ L+ + L Sbjct: 93 NNTLTQL-----MEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSE--LVSAN--RL 143 Query: 202 FTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMN--LPLE 259 F + + + + + + LD + + IN+++ T ++ +P + Sbjct: 144 FGDKSITFNETY-QDISEVVYGAKLQPLDFKGNAEQSRLTINQWISNKTEGRITDVIPPQ 202 Query: 260 GVSTDSTLFFNTYVHFQG--KMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQ 317 ++ + L ++F+G K + + T F+ + S SV M+ F++ A+ Sbjct: 203 AINEFTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSVLMMYQESKFRYRRVAE 262 Query: 318 NNFSVTRVPL-GESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLE 376 + V +P G+ +T++LI P+ L +VE + W+ + + +P+ Sbjct: 263 ST-QVLELPFKGDDITMVLILPKLEKTLAKVEQELTPDMLQEWLDELTETLLVVHMPRFR 321 Query: 377 IRGSYNLQDLLAQAKLSTLLGAEAN----LGKMGDTNPRVGEVLNSILLEL-QAGEEEQP 431 I S+++++ L L L E + + G ++ V + + LE+ + G E Sbjct: 322 IEDSFSVKEQLQDMGLEDLFSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVNEEGSEAAA 381 Query: 432 TESAQQPG---SPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + G + + + + PFL I E + F+GRV NP Sbjct: 382 STVISIAGRSLNSDRVTFKANRPFLVLIREVALNTIIFMGRVANP 426 >2R9Y-A nrPDB Length = 430 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 96/393 (24%), Positives = 149/393 (37%), Gaps = 39/393 (9%) Query: 88 AEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQ 147 AE+ +R AQ M F + S +S VLSP ++ L LG+ + T Sbjct: 15 AEETRRLAQAMMAFTTDLFSLVAQTS----TSSNLVLSPLSVALALSHLALGAQNQTLHS 70 Query: 148 LQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGL 207 L +L + G C L H Q L P ++ G Sbjct: 71 LHRVLHM--NTGSCLPHLLSH-------FYQNL----------GPGTIRLAARIYLQKGF 111 Query: 208 RLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTL 267 +K F+E A P L + LA IN++V+ T K+ L + + L Sbjct: 112 PIKDDFLEQSERLFGAK-PVKLTGKQEEDLA--NINQWVKEATEGKIEDFLSELPDSTVL 168 Query: 268 FFNTYVHFQGKMR-GFS-QLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSD-AQNNFSVTR 324 +HF G R F LT F +D +VSV M+ W Q V Sbjct: 169 LLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAH 228 Query: 325 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTW--IKNPP--PRAIRLTLPQLEIRGS 380 P +++ +++ P + + EVL LTW + +P R ++ LP+L ++ Sbjct: 229 FPFKNNMSFVVVMP-TYFEWNVSEVLAN----LTWDTLYHPSLQERPTKVWLPKLHLQQQ 283 Query: 381 YNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGS 440 +L L+Q L L +L + + N V V + +EL E ++ Sbjct: 284 LDLVATLSQLGLQELFQG-PDLRGISEQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNR 342 Query: 441 PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + T++ PFLF I E G F+G V NP Sbjct: 343 MSLSSFTVNRPFLFFIMEDTIGVPLFVGSVRNP 375 >4DY0-A nrPDB Length = 379 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 81/386 (20%), Positives = 162/386 (41%), Gaps = 39/386 (10%) Query: 105 GFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSR 164 G +++ + ++R V+SP + L LG+ T QL +++ R Sbjct: 16 GIQVFNQIVKSRP-HDNIVISPHGIASVLGMLQLGADGRTKKQLAMVM-----------R 63 Query: 165 LDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV-ESLGPFTPA 223 + V L+ + +V++ + + +F ++ PFV + F Sbjct: 64 YGVNGVGKILKKINKAIVSKKNKD-----IVTVANAVFVKNASEIEVPFVTRNKDVFQCE 118 Query: 224 IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL-----EGVSTDSTLFFNTYVHFQG- 277 + R+++ DP A IN +V+ T ++ L +GV T L V+F+G Sbjct: 119 V--RNVNFE-DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLT--RLVLVNAVYFKGL 173 Query: 278 -KMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNN---FSVTRVPL-GESVT 332 K R + T F + S VPML+ F+ S + N ++ +P GES++ Sbjct: 174 WKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESIS 233 Query: 333 LLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAK 391 +L+ P + ++ L + + +W+ P+ +++ LP+ +L++ L Sbjct: 234 MLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLG 293 Query: 392 LSTLL-GAEANLGKM--GDTNPRVGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLDVT 447 ++ + ++AN K+ G N V +L +E+ + G + +A Sbjct: 294 ITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFI 353 Query: 448 LSSPFLFAIYERDSGALHFLGRVDNP 473 + PFLF I +GA+ F+G+++ P Sbjct: 354 VDRPFLFFIRHNPTGAVLFMGQINKP 379 >6F02-A nrPDB Length = 389 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 90/393 (22%), Positives = 150/393 (38%), Gaps = 49/393 (12%) Query: 104 MGFRMYKML-SEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCT 162 FR Y ++ SE G SP ++ LG+ + SQ+ LG + E Sbjct: 14 FAFRFYYLIASETPG--KNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---L 68 Query: 163 SRLDGHKVLTALQAVQGL----LVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV-ESL 217 S D H+ L L L T+ GS+ LF + L+ F+ +++ Sbjct: 69 SESDVHRGFQHLLHTLNLPGHGLETRVGSA------------LFLSHNLKFLAKFLNDTM 116 Query: 218 GPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQG 277 + +F + D V Q IN V+ T K+ + + D + Y++F+ Sbjct: 117 AVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 173 Query: 278 KMRG--FSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHW--SDAQNNFSVTRVPLGESVTL 333 S T +F+VD +T+V VPM+ HW D SV R+ T+ Sbjct: 174 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQE-HHWYLHDRYLPCSVLRMDYKGDATV 232 Query: 334 LLIQPQCASDLDRVEVLVFQHDFLTW----IKNPPPRAIRLTLPQLEIRGSYNLQDLLAQ 389 I P + +E ++ + W K + + L LP+ I GSY L +L + Sbjct: 233 FFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPR 291 Query: 390 AKLSTLLGAEANL-GKMGDTNPRVGEVLNSILLELQAGEEEQPTE--------SAQQPGS 440 + L A+L G + + L++ E SAQ + Sbjct: 292 LGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT--N 349 Query: 441 PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 +L + PFL I+ + ++ FLG+V +P Sbjct: 350 RHIL--RFNRPFLVVIFSTSTQSVLFLGKVVDP 380 >6F4U-A nrPDB Length = 341 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 74/314 (23%), Positives = 121/314 (38%), Gaps = 36/314 (11%) Query: 104 MGFRMYKML-SEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCT 162 FR Y ++ SE G SP ++ LG+ + SQ+ LG + E Sbjct: 12 FAFRFYYLIASETPG--KNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---L 66 Query: 163 SRLDGHKVLTALQAVQGL----LVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV-ESL 217 S D H+ L L L T+ GS+ LF + L+ F+ +++ Sbjct: 67 SESDVHRGFQHLLHTLNLPGHGLETRVGSA------------LFLSHNLKFLAKFLNDTM 114 Query: 218 GPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQG 277 + +F + D V Q IN V+ T K+ + + D + Y++F+ Sbjct: 115 AVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 171 Query: 278 KMRG--FSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHW--SDAQNNFSVTRVPLGESVTL 333 S T +F+VD +T+V VPM+ HW D SV R+ T+ Sbjct: 172 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQE-HHWYLHDRYLPCSVLRMDYKGDATV 230 Query: 334 LLIQPQCASDLDRVEVLVFQHDFLTW----IKNPPPRAIRLTLPQLEIRGSYNLQDLLAQ 389 I P + +E ++ + W K + + L LP+ I GSY L +L + Sbjct: 231 FFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPR 289 Query: 390 AKLSTLLGAEANLG 403 + L A+L Sbjct: 290 LGFTDLFSKWADLS 303 >2XN5-A nrPDB Length = 350 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 36/175 (20%), Positives = 76/175 (43%), Gaps = 4/175 (2%) Query: 238 AAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRG-F--SQLTGLHEFWVD 294 A Q+IN V+ T K+ ++ + ++ + Y+HF+ + F S+ F +D Sbjct: 138 AKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLID 197 Query: 295 NSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQH 354 +T+V VPM+ + H D + N +V ++ ++ L + P+ ++ VE + Sbjct: 198 KTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPK-EGQMESVEAAMSSK 256 Query: 355 DFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTN 409 W + + L +P+ I +Y+L L + + A+ + + N Sbjct: 257 TLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDN 311 >3NDA-A nrPDB Length = 377 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 55/258 (21%), Positives = 113/258 (43%), Gaps = 20/258 (7%) Query: 228 SLDLSTDPVLAAQKINRFVQAVTGWKM-NLPLEGVSTDSTLFFNTYVHFQGKMRG--FSQ 284 +D + +P A +N +V+ T K+ L E + D+ L ++F+G+ + Sbjct: 124 KVDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTAFVKE 183 Query: 285 LTGLHEFWVDNSTSVSVPM--LSGTGNFQHWSDAQNNFSVTRVPL-GESVTLLLIQPQCA 341 T +F+ T V V L ++ + D Q V +P G T+ ++ P+ Sbjct: 184 HTEKRQFFNGGVTPVEVDTMRLEARIKYRFFDDLQ--VEVVELPYRGLDYTMAILLPKEN 241 Query: 342 SDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEAN 401 + ++ ++ + F ++ + R I + LP+ ++ Y+L+ L + + + A+ Sbjct: 242 TGVEGLKQNLTIDRFQNYLSDLRERKITVLLPKFKLETKYSLKAPLQSLGIKQIFESGAD 301 Query: 402 LGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPG--------SPEVLDVTLSSPFL 453 L + D + RV V + ++E+ E+ T +A G PE + + PFL Sbjct: 302 LSGINDGSLRVSAVEHKAVVEVN----EEGTVAAATTGVVIVPYSLGPEPVVFRVDHPFL 357 Query: 454 FAIYERDSGALHFLGRVD 471 F I + + F+G+V+ Sbjct: 358 FFIRNTRTDDIFFVGQVN 375 >5NCS-A nrPDB Length = 375 Score = 41.2 bits (95), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 58/291 (19%), Positives = 128/291 (43%), Gaps = 24/291 (8%) Query: 196 STVVGL----FTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTG 251 ST +G+ + G +K+PF+ + A +++D S+ L A IN + T Sbjct: 88 STTIGMANSIWYKQGELVKEPFILANRTHYDAEV-KAVDFSSPATLPA--INGWCAQKTN 144 Query: 252 WKMNLPLEGVSTDSTLFFNTYVHFQGK-MRGFSQL-TGLHEFWVDNSTSVSVPMLSGTGN 309 K+ L+ + ++ ++ V+F+G + F + T F + T+ V M++ Sbjct: 145 DKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSDTKRAPFRKADGTTQEVNMMAQKST 204 Query: 310 FQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIR 369 F + +D + ++++ + + D +E L +H + IK P + Sbjct: 205 FGYTTDECCQYLEMDYGNKAFSMIVMLPNEGQTTRDVIEQLDNKH-WSMIIKGIRPTQVS 263 Query: 370 LTLPQLEIRGSYNLQD-LLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEE 428 L +P+ + Y L+ +L + ++ A+ + D + V++ +++ + Sbjct: 264 LRMPRFKTECKYGLEKKILPEMGMNVPFTETADFPGITDAAIFISRVIHKTFVQV----D 319 Query: 429 EQPTESAQ-------QPGSPEV--LDVTLSSPFLFAIYERDSGALHFLGRV 470 E+ TE+A + SP ++ ++ PF+FAI E+ +G + F+G + Sbjct: 320 EEGTEAAAVTAVEMVKTSSPSTTPINFHINKPFVFAIREKSTGVILFIGEI 370 >4GA7-A nrPDB Length = 389 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 61/263 (23%), Positives = 113/263 (42%), Gaps = 18/263 (6%) Query: 228 SLDLSTDPVLAAQKINRFVQAVTGWKM-NLPLEGVSTDST-LFFNTYVHFQG--KMRGFS 283 S+D A + IN++V+ T K+ L G+ + T L ++F+G K + Sbjct: 128 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK 187 Query: 284 QLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GESVTLLLIQPQCAS 342 + T F ++ +V M+ F + V +P GE ++++++ P Sbjct: 188 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 247 Query: 343 D----LDRVEVLVFQHDFLTWIK--NPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLL 396 D L ++E + W K N + ++LP+ ++ SY L LA+ + L Sbjct: 248 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 307 Query: 397 GA-EANLGKM-GDTNPRVGEVLNSILLELQAGEEEQPTESAQQP----GSPEVLDVTLSS 450 + +A+L M G + + ++++ +E+ E +A PE + T Sbjct: 308 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMDDPEE-NFTADH 366 Query: 451 PFLFAIYERDSGALHFLGRVDNP 473 PFLF I SG++ FLGR +P Sbjct: 367 PFLFFIRHNSSGSILFLGRFSSP 389 >1C5G-A nrPDB Length = 402 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 80/391 (20%), Positives = 162/391 (41%), Gaps = 33/391 (8%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 VA +A+ G R+++ +++A V SP + L L + T Q+Q +G Sbjct: 31 VAHLASDFGVRVFQQVAQASK-DRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF-- 87 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 ++D + AL+ + L+ G ++ + ST +F L+L Q F+ Sbjct: 88 -------KIDDKGMAPALRHLYKELM---GPWNKDEI--STTDAIFVQRDLKLVQGFMPH 135 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVT-GWKMNLPLEG-VSTDSTLFFNTYVH 274 + + +D S + A IN +V+ T G NL +G V + L ++ Sbjct: 136 FFRLFRSTV-KQVDFS-EVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALY 193 Query: 275 FQGKMRGFSQLTGLHE--FWVDNSTSVSVPMLSGTGNFQHWSDAQ---NNFSVTRVPL-G 328 F G+ + + H F + ++VSVPM++ T F + + + + +P G Sbjct: 194 FNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHG 253 Query: 329 ESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLL 387 +++++ + P + L + ++ W N L LP+ + +L+ L Sbjct: 254 DTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPL 313 Query: 388 AQAKLSTLLGA-EANLGKMGDTNP-RVGEVLNSILLELQAGEEEQPTESA---QQPGSPE 442 ++ + +A+ + D P V + L + +E+ + +A +PE Sbjct: 314 ENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPE 373 Query: 443 VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 ++ + PFLF + +G + F+G+V P Sbjct: 374 --EIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402 >2PEF-A nrPDB Length = 373 Score = 35.8 bits (81), Expect = 0.037, Method: Compositional matrix adjust. Identities = 56/283 (19%), Positives = 113/283 (39%), Gaps = 42/283 (14%) Query: 211 QPFVESLGPFTPA-IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFF 269 + F++ + + A IF + D ST IN +V++ T ++ L + + ++ Sbjct: 106 KDFLQIIADYYKADIFKAAFDSST-----VSDINNWVKSKTNGMIDKILNKIDPEDVMYL 160 Query: 270 NTYVHFQGKMRGFSQLTGLHEFWVDNSTSV-----SVPMLSGTGNFQHWSDAQNNFSVTR 324 V F + + +HE D T V V ++ N + + +N + Sbjct: 161 INAVAFDAEWETVYEKASVHE---DIFTDVYGNRQKVEFMNSEENL--YIEEENAVGFVK 215 Query: 325 VPLGESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNL 383 + + I P + S + ++ L Q F+ IKN +R +LP+ + + + Sbjct: 216 PYAKNHYSFVAILPDENISVNEYIKTLTGQK-FIDLIKNAKITLVRASLPKFKYEYTIKM 274 Query: 384 QDLLAQAKLS-TLLGAEANLGKMGDT---NPRVGEVLNSILLELQAGEEEQPTESAQQPG 439 + L ++ L +A+ K+G + N + EVL+ + + E + G Sbjct: 275 NETLESLGMTDAFLPDKADFSKLGKSDIGNLYISEVLHKTFISVD--------ELGTKAG 326 Query: 440 SPEVLDVT------------LSSPFLFAIYERDSGALHFLGRV 470 + +D+T L+ PF+FAI + + F+G V Sbjct: 327 AVTSVDITAAGIPVNFKTVKLNRPFIFAIIDNSTNLPIFIGTV 369 >3LE2-A nrPDB Length = 393 Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust. Identities = 68/317 (21%), Positives = 129/317 (40%), Gaps = 32/317 (10%) Query: 182 VTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQK 241 V GS++ P L S G + L K F + L A ++ D + V + Sbjct: 82 VLADGSANGGPKL-SVANGAWIDKSLSFKPSFKQLLEDSYKAASNQA-DFQSKAVEVIAE 139 Query: 242 INRFVQAVTGWKMNLPLEGVSTDS--TLFFNTYVHFQGKM-RGFSQ-LTGLHEFWVDNST 297 +N + + T + L S DS L F ++F+G F + LT EF + + Sbjct: 140 VNSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGN 199 Query: 298 SVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-----GESVTLLLIQPQCASDL-DRVEVLV 351 V+ P + T + + A + F V +P ++ P + L D ++ +V Sbjct: 200 KVTAPFM--TSKKKQYVSAYDGFKVLGLPYLQGQDKRQFSMYFYLPDANNGLSDLLDKIV 257 Query: 352 FQHDFLTWIKNPPPRAIRL---TLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDT 408 FL + P R +++ +P+ + ++ ++L L++ E L +M ++ Sbjct: 258 STPGFLD--NHIPRRQVKVREFKIPKFKFSFGFDASNVLKGLGLTSPFSGEEGLTEMVES 315 Query: 409 NPRVGEVL--NSILLELQAGEEEQPTESAQQPG----------SPEVLDVTLSSPFLFAI 456 P +G+ L ++I + E+ TE+A + +D PFL + Sbjct: 316 -PEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIKLRGLLMEEDEIDFVADHPFLLVV 374 Query: 457 YERDSGALHFLGRVDNP 473 E +G + F+G+V +P Sbjct: 375 TENITGVVLFIGQVVDP 391 >1SNG-A nrPDB Length = 370 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 4/113 (3%) Query: 367 AIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILL---EL 423 ++ L LP+ E+ + L ++LA+A + TL A A+L + V V++ L E Sbjct: 253 SVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTVPLYVDTVIHQARLRVDER 312 Query: 424 QAGEEEQPTESAQQPGS-PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQN 475 A G+ P + S F I R GA+ FLG + +P + Sbjct: 313 GAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRRGAILFLGSIADPHD 365 >3PZF-A nrPDB Length = 397 Score = 31.6 bits (70), Expect = 0.84, Method: Compositional matrix adjust. Identities = 39/184 (21%), Positives = 71/184 (38%), Gaps = 18/184 (9%) Query: 304 LSGTGNFQHWSDAQNNFSVTRVPL-GESVTLLLIQPQ----CASDLDRVEVLVFQHDFLT 358 + G F + + A + R+P G + + I P LDR+ H L Sbjct: 216 MEQNGQFYYDNSADLGAQILRLPYRGNKLAMYFILPNPDNTVNQVLDRINSASL-HQALW 274 Query: 359 WIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANL-----GKMGDTNPRVG 413 +++ + +TLP+ + S L + L Q + + A+L G+ RV Sbjct: 275 YME---ENEVNVTLPKFKFDFSEQLNEPLQQVGIREIFSQNASLPLLARGRGARDEVRVS 331 Query: 414 EVLNSILLEL-QAGEEEQPTESAQ---QPGSPEVLDVTLSSPFLFAIYERDSGALHFLGR 469 + + + + G E Q + G V + PF+F I + G + F G+ Sbjct: 332 RIFQKAGITINELGSEAYAATEIQLVNKFGGDGVQIFNANRPFIFFIEDETLGTMLFAGK 391 Query: 470 VDNP 473 ++NP Sbjct: 392 IENP 395 >3STO-A nrPDB Length = 406 Score = 31.2 bits (69), Expect = 1.00, Method: Compositional matrix adjust. Identities = 61/290 (21%), Positives = 119/290 (41%), Gaps = 23/290 (7%) Query: 200 GLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFV-QAVTGWKMNLPL 258 G+F +++ F ES+ + + +D S + A IN +V Q G Sbjct: 120 GIFVEKTYEVERRFNESIANDSEGEL-KQVDFS-NRTSATVDINDWVDQQSNGLLEKFFT 177 Query: 259 EGVSTDSTLFFNTYVHFQGKMRGFSQ------LTGLHEFWVDNSTSVSVPMLSGTGNFQH 312 + + D+ + +F R F Q T +F++ ++V M++ G ++ Sbjct: 178 DDIPDDTAMILVNVFYF----RDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKY 233 Query: 313 WSDAQNNFSVTRVPLGES-VTLLLIQPQCASDLDRVEVLVFQHDFLT-WIKNPPPRAIRL 370 F + PL + T +++ P L+ L+ + L+ ++KN + L Sbjct: 234 GKFEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSL 293 Query: 371 TLPQLEIRGSYNLQDLLAQAKLSTLLG-AEANL-GKMGDTNPRVGEVLNSILLELQAGEE 428 LP+ ++ + +L L + L +++L G + N V E + + +L+L Sbjct: 294 RLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGI 353 Query: 429 EQPTESAQ--QPGS---PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 E T ++ P S PEV D ++ PF+ IY++ +V NP Sbjct: 354 EATTVTSPIFVPFSAIIPEV-DFHVTHPFICFIYDQQLTMPIMAAKVMNP 402 >4YH2-A nrPDB Length = 222 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 22/32 (68%) Query: 362 NPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLS 393 +PP RA++LTL L + Y D++A+A+LS Sbjct: 12 SPPVRAVKLTLAALNLTYEYVNVDIVARAQLS 43 >6BQ9-A nrPDB Length = 496 Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 23/34 (67%), Gaps = 1/34 (2%) Query: 372 LPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKM 405 L +++IRG + + L QAKL LLG+EA L K+ Sbjct: 438 LEEMKIRGEQD-ELLKEQAKLQALLGSEAKLRKL 470 >6C5C-A nrPDB Length = 390 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 14/84 (16%) Query: 91 RQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSF----------YLGS 140 R +A V+ G R G A AVL+P AL G VS YLG Sbjct: 244 RVKAGVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGI 303 Query: 141 LDPTA----SQLQVLLGVPVKEGD 160 L P A S+ V G+PV D Sbjct: 304 LPPVAVARLSKCLVAYGLPVSIDD 327 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2WXZ-C nrPDB 565 e-161 2WXX-A nrPDB 548 e-156 5M3Y-A nrPDB 487 e-138 6EE5-A nrPDB 459 e-129 5INW-A nrPDB 393 e-109 6HGE-B nrPDB 391 e-109 1ATT-A nrPDB 389 e-108 2VDY-A nrPDB 387 e-108 4EB1-I nrPDB 385 e-107 2OL2-A nrPDB 367 e-102 3NE4-A nrPDB 363 e-101 4Y40-A nrPDB 358 3e-99 1YXA-A nrPDB 354 4e-98 4ZK0-A nrPDB 354 6e-98 2V95-A nrPDB 354 6e-98 1BY7-A nrPDB 352 2e-97 5HGC-A nrPDB 350 1e-96 6F02-A nrPDB 347 5e-96 3DY0-A nrPDB 338 4e-93 1JMJ-A nrPDB 333 1e-91 4AJT-A nrPDB 331 4e-91 3NDA-A nrPDB 331 5e-91 4GA7-A nrPDB 325 3e-89 4DY0-A nrPDB 323 1e-88 1UHG-A nrPDB 320 9e-88 6F4U-A nrPDB 317 7e-87 1QMB-A nrPDB 317 1e-86 3ZHA-A nrPDB 316 1e-86 2R9Y-A nrPDB 312 2e-85 4P0F-A nrPDB 312 2e-85 4KDS-A nrPDB 312 3e-85 4AJU-A nrPDB 309 2e-84 5NCS-A nrPDB 303 8e-83 4DTE-A nrPDB 298 2e-81 1IMV-A nrPDB 296 9e-81 2XN5-A nrPDB 294 5e-80 3F02-A nrPDB 290 1e-78 2OAY-A nrPDB 276 2e-74 6CJ7-A nrPDB 255 3e-68 1JJO-C nrPDB 244 5e-65 Sequences not found previously or not previously below threshold: 1HLE-A nrPDB 294 6e-80 1C5G-A nrPDB 283 1e-76 2H4P-A nrPDB 277 8e-75 2H4Q-A nrPDB 277 9e-75 3LW2-A nrPDB 267 6e-72 5NCU-A nrPDB 267 9e-72 1XQJ-A nrPDB 235 4e-62 1K9O-I nrPDB 224 5e-59 1SEK-A nrPDB 221 4e-58 3LE2-A nrPDB 214 6e-56 1C8O-A nrPDB 212 2e-55 3OZQ-A nrPDB 210 1e-54 3STO-A nrPDB 202 3e-52 3PZF-A nrPDB 202 4e-52 2PEF-A nrPDB 197 1e-50 1M93-B nrPDB 189 2e-48 6BJ5-B nrPDB 159 2e-39 1SNG-A nrPDB 147 1e-35 1MTP-A nrPDB 126 2e-29 5C98-A nrPDB 118 7e-27 4R9I-A nrPDB 79 6e-15 2P6F-A nrPDB 36 0.029 5LN3-Z nrPDB 34 0.11 4XGV-A nrPDB 32 0.55 4NOV-A nrPDB 32 0.88 4GAX-A nrPDB 30 1.7 4GWP-B nrPDB 30 2.1 6GCS-K nrPDB 30 2.2 3PPS-A nrPDB 30 2.4 3EC7-A nrPDB 29 4.0 3AJB-A nrPDB 29 4.1 2CYC-A nrPDB 29 6.0 >2WXZ-C nrPDB Length = 453 Score = 565 bits (1457), Expect = e-161, Method: Composition-based stats. Identities = 453/453 (100%), Positives = 453/453 (100%) Query: 25 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 84 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE Sbjct: 1 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 60 Query: 85 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 144 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 204 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA Sbjct: 121 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 180 Query: 205 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 264 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD Sbjct: 181 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 240 Query: 265 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 324 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR Sbjct: 241 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 300 Query: 325 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 444 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL Sbjct: 361 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 420 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 477 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV Sbjct: 421 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 453 >2WXX-A nrPDB Length = 453 Score = 548 bits (1412), Expect = e-156, Method: Composition-based stats. Identities = 391/453 (86%), Positives = 416/453 (91%) Query: 25 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 84 DRVYIHPFHLLY++KSTCAQLENPSVETLPE TFEPVPIQAKTSPV+EKTL D+LVLA E Sbjct: 1 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 60 Query: 85 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 144 KLE EDR+RAAQVAMI NF+GFRMYKML+EA ASGA+LSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 204 ASQLQ LL VPVKEGDCTSRLDGHKVL AL+AVQGLLVTQGGSSSQTPLLQS VVGLFTA Sbjct: 121 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGLFTA 180 Query: 205 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 264 PG RLK FV+SL FTPA+FPRSLDLSTDPVLA +KINRF++AVTGWKMNLPLEGVSTD Sbjct: 181 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 240 Query: 265 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 324 STL FNTYVHFQG MRGFSQL G+HEFWVDNS SVSVPM+SGTGNFQHWSDAQNNFSVT Sbjct: 241 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 300 Query: 325 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGE TLLLIQP C SDLDRVE L+FQ+D LTWI+NPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGERATLLLIQPHCISDLDRVEALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 444 DLLA+ KL TLLGAEANL +GDTNPRVGEVLNSILLEL+AGEEEQPT S QQPGSPE L Sbjct: 361 DLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 420 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 477 DVTLSSPFLFAIYE+DSG LHFLGRV+NPQ+VV Sbjct: 421 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 453 >5M3Y-A nrPDB Length = 458 Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats. Identities = 289/450 (64%), Positives = 340/450 (75%), Gaps = 3/450 (0%) Query: 25 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 84 DRVYIHPFHL+ +++STC QL + +PTF P PIQAKTSPVDEK L+D+LVL Sbjct: 1 DRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAA 60 Query: 85 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGA-VLSPPALFGTLVSFYLGSLDP 143 KL+ ED+ RAA V M+ANF+GFR+Y M SE GV GA VLSP A+FGTL S YLG+LD Sbjct: 61 KLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDH 120 Query: 144 TASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFT 203 TA +LQ +LGVP K+ CTSRLD HKVL+ALQAVQGLLV QG + SQ LL STVVG+FT Sbjct: 121 TADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFT 180 Query: 204 APGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVST 263 APGL LKQPFV+ L +TP + PRSLD T+ +AA+KI+RF+QAVTGWK L G S Sbjct: 181 APGLHLKQPFVQGLALYTPVVLPRSLDF-TELDVAAEKIDRFMQAVTGWKTGSSLMGASV 239 Query: 264 DSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVT 323 DSTL FNTYVHFQGKM+GFS L EFWVD STSVSVPMLSG G FQHWSD Q+ FSVT Sbjct: 240 DSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDQSTSVSVPMLSGMGTFQHWSDIQDQFSVT 299 Query: 324 RVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNL 383 +VP ES +LLLIQP ASDLD+VE L FQ + L W+K PR I LT+PQL ++GSY+L Sbjct: 300 QVPFTESASLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDL 359 Query: 384 QDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEV 443 QDLLAQA+L +L E NL K+ + RVGEVLNSI EL+A E E PTES QQ PEV Sbjct: 360 QDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADERE-PTESTQQLNKPEV 418 Query: 444 LDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 L+VTL+ PFLFA+Y++ + ALHFLGRV NP Sbjct: 419 LEVTLNRPFLFAVYDQSATALHFLGRVANP 448 >6EE5-A nrPDB Length = 379 Score = 459 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 98/381 (25%), Positives = 171/381 (44%), Gaps = 24/381 (6%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 ++A F +Y+ L+++ SP ++ L LG+ T +Q+ LG Sbjct: 20 KLAEANTDFAFSLYRELAKS-SPDKNIFFSPVSISSALAMLSLGAKGDTHTQILEGLGFN 78 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 S D H Q Q LL T L T GLF L+L F+E Sbjct: 79 -------SEADIH------QGFQHLLQTLNRPK---GLQLKTANGLFVDKSLKLLDSFLE 122 Query: 216 SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHF 275 A S+D DP A ++IN +V+ T K+ L+ + +D+ L ++F Sbjct: 123 DSKKLYQAE-AFSVDF--DPEEAKKQINDWVEKQTNGKIKDLLKDLDSDTVLVLVNAIYF 179 Query: 276 QGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTL 333 +GK + + T +F VD T+V VPM+S G F ++ D + + V +P + ++ Sbjct: 180 KGKWKKPFDPENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDDELSCKVLELPYKGNASM 239 Query: 334 LLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLS 393 L+I P L +E + W+K+ R++ L LP+ +I G+Y+L+++L+ ++ Sbjct: 240 LIILPD-EGGLQHLEQSLTPETLSKWLKSLTRRSVELYLPKFKIEGTYDLKEVLSNLGIT 298 Query: 394 TLLGAEANLGKMGDTNPRVGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLDVTLSSPF 452 L A+L + + V + ++ +LE+ + G E + + PF Sbjct: 299 DLFSPGADLSGITEEKLYVSKAVHKAVLEVNEEGTEAAAATFLEAIPMSIPPEFKADRPF 358 Query: 453 LFAIYERDSGALHFLGRVDNP 473 LF I E +G++ F+G+V NP Sbjct: 359 LFLIRENKTGSILFMGKVVNP 379 >5INW-A nrPDB Length = 421 Score = 393 bits (1009), Expect = e-109, Method: Composition-based stats. Identities = 102/432 (23%), Positives = 177/432 (40%), Gaps = 29/432 (6%) Query: 24 GDRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLAT 83 G+R Y+ PFHL+ S S A E P E P P+ SP Sbjct: 1 GERPYMQPFHLIPPSLSVQAT-EQPLASN--EAWDYPEPLAPGQSPAASSEEGSSEEKGD 57 Query: 84 EKLEAEDRQRAA----------QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTL 133 E+ D + ++A N +GFR+YK + G A SP ++ L Sbjct: 58 EREPHGDEGKRGRKDKKKSKTQRIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASAL 117 Query: 134 VSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPL 193 G+ T ++L LG L G K +++ L S+ L Sbjct: 118 GVVTAGANGSTRAELDTALGF-------KEFLHGKKKAKSMKYFARLNGALYKRSAGFEL 170 Query: 194 LQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWK 253 + V +F+ GL L + F ++ + RS+D D A + +N +++ VT K Sbjct: 171 MGKNV--VFSKKGLWLYRQFTRTVAHLFKSNV-RSVDF-GDSKNAVELMNAYIEKVTSKK 226 Query: 254 MNLPLEGVSTDSTLFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQ 311 + V TD++L ++F+G + LT FWV++S S+ VP + Sbjct: 227 FPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPDLTKNVRFWVNSSYSMMVPTMHQRAKLS 286 Query: 312 HWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPP--RAIR 369 + D + +V ++P ++L+I P DL +VE V Q W+ P ++ Sbjct: 287 YTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEEWLSLLGPSNHYVQ 346 Query: 370 LTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKM-GDTNPRVGEVLNSILLELQAGEE 428 L+LP+ +I SY+L+ L+ +S++ A+L ++ G V ++ + +L + Sbjct: 347 LSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRITGMQKLHVDKITHKSVLHVNEEGT 406 Query: 429 EQPTESAQQPGS 440 E E+ + Sbjct: 407 EAKAETVVGIMA 418 >6HGE-B nrPDB Length = 409 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 95/424 (22%), Positives = 174/424 (41%), Gaps = 40/424 (9%) Query: 66 KTSPVDEKTLRDKLVLATEKLEAEDRQRAAQ----VAMIANFMGFRMYKMLSEARGVASG 121 + SP+DE E L E++ R +A F +YK L + Sbjct: 11 QNSPLDE-----------ENLTQENQDRGTHVDRGLASANVDFAFSLYKQLV-LKAPDKN 58 Query: 122 AVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLL 181 + SP ++ L LG+ + T +++ L + E TS + H Q+ Q LL Sbjct: 59 VIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTE---TSEAEIH------QSFQHLL 109 Query: 182 VTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQK 241 T SS + L S +F L L F E + + D D A + Sbjct: 110 RTLNQSSDELQL--SMGNAMFVKEQLSLLDRFTEDAKRLYGSE-AFATDF-QDSAAAKKL 165 Query: 242 INRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSV 299 IN +V+ T K+ ++ + + + + Y+ F+ K Q T F++ V Sbjct: 166 INDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWV 225 Query: 300 SVPMLSGTG-NFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLT 358 VPM+S ++ D + + +V ++ + + L I P ++ VE ++ + Sbjct: 226 MVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPD-QDKMEEVEAMLSRETLNR 284 Query: 359 WIKNPPPRAI-RLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKM-GDTNPRVGEVL 416 W + R I L LP+ I YNL D+L Q + ++A+L + G N V +V+ Sbjct: 285 WGDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVV 344 Query: 417 NSILLEL-QAGEEEQPTESAQQPGSPEVLD----VTLSSPFLFAIYERDSGALHFLGRVD 471 + +L++ + G E + + +++ V + PFL I + + ++ F+ +V Sbjct: 345 HKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVDHFTWSIFFMSKVT 404 Query: 472 NPQN 475 NP+ Sbjct: 405 NPKQ 408 >1ATT-A nrPDB Length = 429 Score = 389 bits (1000), Expect = e-108, Method: Composition-based stats. Identities = 79/433 (18%), Positives = 170/433 (39%), Gaps = 28/433 (6%) Query: 55 EPTFEPV-PIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLS 113 +P PV P+ S + T + +K+ +R +++ + Y+ L+ Sbjct: 8 KPRDIPVNPMCIYRSSEKKATEGQG---SEQKIPGATNRRVWELSKANSHFATAFYQHLA 64 Query: 114 EARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTA 173 +++ LSP ++ LG+ + T +QL + V + D S ++ Sbjct: 65 DSKNNNDNIFLSPLSISTAFAMTKLGACNNTLTQL-----MEVFKFDTISEKTSDQIHFF 119 Query: 174 LQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLST 233 + L + SS+ + LF + + + + + + LD Sbjct: 120 FAKLNCRLYRKANKSSE----LVSANRLFGDKSITFNETY-QDISEVVYGAKLQPLDFKG 174 Query: 234 DPVLAAQKINRFVQAVTGWKMNL--PLEGVSTDSTLFFNTYVHFQGKM--RGFSQLTGLH 289 + + IN+++ T ++ P + ++ + L ++F+G + + T Sbjct: 175 NAEQSRLTINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLWKSKFSPENTRKE 234 Query: 290 EFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GESVTLLLIQPQCASDLDRVE 348 F+ + S SV M+ F++ A++ V +P G+ +T++LI P+ L +VE Sbjct: 235 LFYKADGESCSVLMMYQESKFRYRRVAEST-QVLELPFKGDDITMVLILPKLEKTLAKVE 293 Query: 349 VLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEAN-LGKM-- 405 + W+ + + +P+ I S+++++ L L L E + L + Sbjct: 294 QELTPDMLQEWLDELTETLLVVHMPRFRIEDSFSVKEQLQDMGLEDLFSPEKSRLPGIVA 353 Query: 406 -GDTNPRVGEVLNSILLELQAGEEEQPTES----AQQPGSPEVLDVTLSSPFLFAIYERD 460 G ++ V + + LE+ E + A + + + + + PFL I E Sbjct: 354 EGRSDLYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLNSDRVTFKANRPFLVLIREVA 413 Query: 461 SGALHFLGRVDNP 473 + F+GRV NP Sbjct: 414 LNTIIFMGRVANP 426 >2VDY-A nrPDB Length = 373 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 84/381 (22%), Positives = 157/381 (41%), Gaps = 19/381 (4%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 +A F +YK L A +SP ++ L LG+ T +QL LG + Sbjct: 7 LASANVDFAFSLYKHLV-ALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 65 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 E T G + L L A S T L + LF L L + F Sbjct: 66 TERSETEIHQGFQHLHQLFA-----------KSDTSLEMTMGNALFLDGSLELLESFSAD 114 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQ 276 + + + +++ D A+++IN +V+ T K+ G+ + + L Y+ F+ Sbjct: 115 IKHYYESEVL-AMNF-QDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFK 172 Query: 277 GKMRGFSQL--TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLL 334 G L T F+VD +T V VPM+ + + D++ + ++ + T+ Sbjct: 173 GTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVF 232 Query: 335 LIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLST 394 I P ++ V + + W + L +P++ I G Y+L D+L + ++ Sbjct: 233 FILPDK-GKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIAD 291 Query: 395 LLGAEANLGKMG-DTNPRVGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLDVTLSSPF 452 L +AN ++ D + +V++ +L+L + G E + + + + + PF Sbjct: 292 LFTTQANFSRITQDAQLKSSKVVHKAVLQLNEEGTEAAGAMFLEAIPRSKPIILRFNQPF 351 Query: 453 LFAIYERDSGALHFLGRVDNP 473 + I++ + + FL RV NP Sbjct: 352 IIMIFDHFTWSSLFLARVMNP 372 >4EB1-I nrPDB Length = 440 Score = 385 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 83/441 (18%), Positives = 167/441 (37%), Gaps = 36/441 (8%) Query: 55 EPTFEPV-PIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLS 113 +P P+ P+ SP + T + +K+ +R +++ + Y+ L+ Sbjct: 11 KPRDIPMNPMCIYRSPEKKATE---DEGSEQKIPEATNRRVWELSKANSRFATTFYQHLA 67 Query: 114 EARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTA 173 +++ LSP ++ LG+ + T QL + V + D S ++ Sbjct: 68 DSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQL-----MEVFKFDTISEKTSDQIHFF 122 Query: 174 LQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLST 233 + L + +S+ + LF L + + + + + LD Sbjct: 123 FAKLNCRLYRKANKASK----LVSANRLFGDKSLTFNETY-QDISELVYGAKLQPLDFKE 177 Query: 234 DPVLAAQKINRFVQAVTGWKMNL--PLEGVS--------TDSTLFFNTYVHFQGKM--RG 281 + + IN++V T ++ P E ++ T + L ++F+G + Sbjct: 178 NAEQSRAAINKWVSNKTEGRITDVIPSEAINVLVLVNTRTSTVLVLVNTIYFKGLWKSKF 237 Query: 282 FSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GESVTLLLIQPQC 340 + T F+ + S S M+ G F++ A+ V +P G+ +T++LI P+ Sbjct: 238 SPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGT-QVLELPFKGDDITMVLILPKP 296 Query: 341 ASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEA 400 L +VE + W+ + + +P+ I ++L++ L L L E Sbjct: 297 EKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEK 356 Query: 401 N-LGKM---GDTNPRVGEVLNSILLELQAGEEEQPTESAQQP----GSPEVLDVTLSSPF 452 + L + G + V + + LE+ E +A +P + + PF Sbjct: 357 SKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPF 416 Query: 453 LFAIYERDSGALHFLGRVDNP 473 L I E + F+GRV NP Sbjct: 417 LVFIREVPLNTIIFMGRVANP 437 >2OL2-A nrPDB Length = 395 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 92/400 (23%), Positives = 166/400 (41%), Gaps = 36/400 (9%) Query: 87 EAEDRQRAAQVAMIAN-FMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTA 145 + + A VA + F +Y+ L+ + + SP ++ +L LG+ T Sbjct: 19 DDDKHMVGATVAPSSRRDFTFDLYRALA-SAAPSQNIFFSPVSISMSLAMLSLGAGSSTK 77 Query: 146 SQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAP 205 Q+ LG+ +++ G Q LL L S LFT Sbjct: 78 MQILEGLGLNLQKSSEKELHRG---------FQQLLQELNQPRDGFQL--SLGNALFTDL 126 Query: 206 GLRLKQPFVESLGPFTPA-IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 264 + L+ FV ++ A FP + D A ++IN +V T K+ L+ + ++ Sbjct: 127 VVDLQDTFVSAMKTLYLADTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLLKNLDSN 183 Query: 265 STLFFNTYVHFQGKMRGFSQL--TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSV 322 + + Y+ F+ K T +F+V + T V VPM+S + + D + V Sbjct: 184 AVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRV 243 Query: 323 TRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYN 382 VP + T L I P + +VE + + W+K R + L LP+ I GSY Sbjct: 244 VGVPYQGNATALFILP-SEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQ 302 Query: 383 LQDLLAQAKLSTLLGAEANLGKMG-DTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSP 441 L+ +L +S + + A+L + +N +V E+++ ++E+ +E T +A G+ Sbjct: 303 LEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV----DESGTRAAAATGTI 358 Query: 442 EVL--------DVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + + PFL I + + + FLG+V+ P Sbjct: 359 FTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLGKVNRP 395 >3NE4-A nrPDB Length = 424 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 87/409 (21%), Positives = 165/409 (40%), Gaps = 21/409 (5%) Query: 70 VDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPAL 129 + E D +D ++ F +Y+ L+ + ++ SP ++ Sbjct: 29 LAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAH-QSNSTNIFFSPVSI 87 Query: 130 FGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSS 189 LG+ T ++ L + E H+ Q LL T S Sbjct: 88 ATAFAMLSLGTKADTHDEILEGLNFNLTE---IPEAQIHE------GFQELLRTLNQPDS 138 Query: 190 QTPLLQSTVVGLFTAPGLRLKQPFVESLGPFT-PAIFPRSLDLSTDPVLAAQKINRFVQA 248 Q L +T GLF + GL+L F+E + F + D A ++IN +V+ Sbjct: 139 QLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNF---GDTEEAKKQINDYVEK 193 Query: 249 VTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSG 306 T K+ ++ + D+ Y+ F+GK + T +F VD T+V VPM+ Sbjct: 194 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 253 Query: 307 TGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPR 366 G F + + V + + T + P L +E + +++N R Sbjct: 254 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPD-EGKLQHLENELTHDIITKFLENEDRR 312 Query: 367 AIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNP-RVGEVLNSILLELQA 425 + L LP+L I G+Y+L+ +L Q ++ + A+L + + P ++ + ++ +L + Sbjct: 313 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 372 Query: 426 -GEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 G E + +V + PF+F + E+++ + F+G+V NP Sbjct: 373 KGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 421 >4Y40-A nrPDB Length = 414 Score = 358 bits (919), Expect = 3e-99, Method: Composition-based stats. Identities = 88/416 (21%), Positives = 178/416 (42%), Gaps = 30/416 (7%) Query: 63 IQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGA 122 ++ SP + K L +E + R A ++A +GF++ K L+ Sbjct: 21 MKPSFSPRNYKAL-------SEVQGWKQRMAAKELARQNMDLGFKLLKKLA-FYNPGRNI 72 Query: 123 VLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDG-HKVLTALQAVQGLL 181 LSP ++ LG+ D T +++ G ++ +G H ++ L Sbjct: 73 FLSPLSISTAFSMLCLGAQDSTLDEIKQ--GFNFRKMPEKDLHEGFHYIIHEL------- 123 Query: 182 VTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQK 241 + L S LF L+ ++ F+E F A L + +A ++ Sbjct: 124 -----TQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAE--TILTNFQNLEMAQKQ 176 Query: 242 INRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMR--GFSQLTGLHEFWVDNSTSV 299 IN F+ T K+N +E + + + Y+ F+ + + +T +F+++ ++SV Sbjct: 177 INDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSV 236 Query: 300 SVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTW 359 VPM+ +G +Q D + + ++ +P +++T + I P L +E + F W Sbjct: 237 KVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPD-EGKLKHLEKGLQVDTFSRW 295 Query: 360 IKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMG-DTNPRVGEVLNS 418 R + +++P+L + G+++L+ L+ +S + +L K+ + +VGE ++ Sbjct: 296 KTLLSRRVVCVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHK 355 Query: 419 ILLELQAGEEEQPTESAQQPGSPE-VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 L++ E + Q E L V + P+L IY ++ FLG++ NP Sbjct: 356 AELKMDERGTEGAAGTGAQTLPMETPLCVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411 >1YXA-A nrPDB Length = 398 Score = 354 bits (909), Expect = 4e-98, Method: Composition-based stats. Identities = 84/402 (20%), Positives = 155/402 (38%), Gaps = 24/402 (5%) Query: 82 ATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSL 141 E + + + +A I F +YK L + + V SP ++ L LG+ Sbjct: 12 VQEDHDNGTQLDSLTLASINTDFAFSLYKELV-LKNPDTNIVFSPLSISAALALVSLGAK 70 Query: 142 DPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGL 201 T ++ L + E TS D H Q LL Q + ST L Sbjct: 71 GNTLEEILEGLKFNLTE---TSEADIH------QGFGHLLQRLNQPKDQVQI--STGSAL 119 Query: 202 FTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGV 261 F ++ F E A + D P A + IN +V+ T + + + Sbjct: 120 FIEKRQQILTEFQEKAKTLYQAEAFTA-DF-QQPRQAKKLINDYVRKQTQGMIKELVSDL 177 Query: 262 STDSTLFFNTYVHFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTG-NFQHWSDAQN 318 + + Y++F+ K + T EF+ V VPM+S ++ D + Sbjct: 178 DKRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFYCGKRRPVIVPMMSMEDLTTPYFRDEEL 237 Query: 319 NFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAI-RLTLPQLEI 377 + +V + + + L I P + +VE + W + PR I L LP+ I Sbjct: 238 SCTVVELKYTGNASALFILPD-QGRMQQVEASLQPETLRKWKNSLKPRMIDELHLPKFSI 296 Query: 378 RGSYNLQDLLAQAKLSTLLGAEANLGKM-GDTNPRVGEVLNSILLEL----QAGEEEQPT 432 Y+L+D+L++ + + +A+L + G + RV +V++ +L++ Sbjct: 297 STDYSLEDVLSKLGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGV 356 Query: 433 ESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 + L V + PFL I++ ++ F+ ++ NP+ Sbjct: 357 KFVPMSAKLYPLTVYFNRPFLIMIFDTETEIAPFIAKIANPK 398 >4ZK0-A nrPDB Length = 390 Score = 354 bits (908), Expect = 6e-98, Method: Composition-based stats. Identities = 76/393 (19%), Positives = 160/393 (40%), Gaps = 22/393 (5%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 ++ F +++ +++ + SP ++ L LG+ D TA Q++ +L Sbjct: 4 LSEANTKFMFDLFQQFRKSK--ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61 Query: 157 KEGDCTSRLDGHKVLTA---LQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPF 213 + T + + V + Q LL S+ L LF Q + Sbjct: 62 VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYEL--KIANKLFGEKTYLFLQEY 119 Query: 214 VESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFNT 271 ++++ F S+D + P + +KIN +V++ T K+ + + +++TL Sbjct: 120 LDAIKKFYQTSV-ESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVN 178 Query: 272 YVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGE 329 ++F+G+ + + T +FW + +T S+ M+ +F S V +P Sbjct: 179 AIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKG 238 Query: 330 -SVTLLLIQPQCASDLDRVEVLVFQHDFLTW--IKNPPPRAIRLTLPQLEIRGSYNLQDL 386 ++++++ P L ++E + + W ++N + L LP+ ++ SY+L+D Sbjct: 239 KDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDT 298 Query: 387 LAQAKLSTLLGAEANLGKM-GDTNPRVGEVLNSILL-----ELQAGEEEQPTESAQQPGS 440 L + + +A+L M G + VL+ + +A P S Sbjct: 299 LRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358 Query: 441 PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + + PFLF I + + ++ F GR +P Sbjct: 359 TN-EEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390 >2V95-A nrPDB Length = 371 Score = 354 bits (907), Expect = 6e-98, Method: Composition-based stats. Identities = 80/380 (21%), Positives = 161/380 (42%), Gaps = 21/380 (5%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 +A F +Y+ L A ++SP ++ L LGS +Q LG + Sbjct: 9 LAPTNVDFAFNLYQRLV-ALNPDKNTLISPVSISMALAMVSLGS---AQTQSLQSLGFNL 64 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 E TS + H+ + Q + LL S T L + +F L+LK F+ Sbjct: 65 TE---TSEAEIHQ---SFQYLNYLL-----KQSDTGLEMNMGNAMFLLQKLKLKDSFLAD 113 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQ 276 + + + ++D D A+Q+IN+ V+ T K+ + + ++ Y+ + Sbjct: 114 VKQYYESE-ALAIDFE-DWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLR 171 Query: 277 GKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLL 334 G + T +F+V+ +++V VPM+ +G+ ++ D+ + ++ + T Sbjct: 172 GIWELPFSPENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAF 231 Query: 335 LIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLST 394 I P +D V + + W K PR + L +P+ + +Y+L+D+L + Sbjct: 232 FILPD-QGQMDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSMSDTYDLKDVLEDLNIKD 290 Query: 395 LLGAEANLGKMGDTNPRVGEVLNSILLELQAGEE-EQPTESAQQPGSPEVLDVTLSSPFL 453 LL +++ P +++ +L+L G T A E LD+ + PF+ Sbjct: 291 LLTNQSDFSGNTKDVPLTLTMVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLDIKFNKPFI 350 Query: 454 FAIYERDSGALHFLGRVDNP 473 ++++ + + + +V NP Sbjct: 351 LLLFDKFTWSSLMMSQVVNP 370 >1BY7-A nrPDB Length = 382 Score = 352 bits (903), Expect = 2e-97, Method: Composition-based stats. Identities = 70/392 (17%), Positives = 145/392 (36%), Gaps = 28/392 (7%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 + + ++K L++A LSP ++ T+ Y+GS T Q+ +L Sbjct: 4 LCVANTLFALNLFKHLAKA-SPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNE 62 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 K+ ++ +++ + ++S L +V LF ++ ++ Sbjct: 63 VG------AAADKIHSSFRSLSSAI-----NASTGNYLLESVNKLFGEKSASFREEYIRL 111 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTYVH 274 + + P+++D A +KIN +V+ T K+ L V D+ + V+ Sbjct: 112 CQKYYSSE-PQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVY 170 Query: 275 FQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVT 332 F+GK + +L GL+ F V+++ V M+ + +P V+ Sbjct: 171 FKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVS 230 Query: 333 LLLIQPQCA----SDLDRVEVLVFQHDFLTWI--KNPPPRAIRLTLPQLEIRGSYNLQDL 386 + L+ P + L+ +E + W + + +PQ ++ Y L+ + Sbjct: 231 MFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSI 290 Query: 387 LAQAKLSTLLGAE-ANLGKMGDTN-PRVGEVLNSILLELQAGEEEQPTESAQQPGSPE-- 442 L + AN M + N + EV + ++++ E + Sbjct: 291 LRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGH 350 Query: 443 -VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 PFLF I + + + F GR +P Sbjct: 351 GGPQFVADHPFLFLIMHKITNCILFFGRFSSP 382 >5HGC-A nrPDB Length = 380 Score = 350 bits (897), Expect = 1e-96, Method: Composition-based stats. Identities = 76/390 (19%), Positives = 157/390 (40%), Gaps = 21/390 (5%) Query: 89 EDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQL 148 + A ++ F+ ++ +++ SP ++ LG+ T SQ+ Sbjct: 3 AEAMAALKLVPNNADFAFQFFREVTQ-EAPNKNIFYSPVSISTAFAMLALGARSATQSQI 61 Query: 149 QVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLR 208 L + E +G L+ L + + +F L Sbjct: 62 LEGLAFNLTEIQEKEIHEG---------FHNLIHMLNHPEGGVQL--NMMNAIFVTAALA 110 Query: 209 LKQPFVESLGPFTP-AIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTL 267 L + F++ F + P A ++IN +++ T K+ ++ + + + Sbjct: 111 LLRKFLDDAKALYQLEAFTTDFN---KPTEAEKQINDYIERKTHGKITNLVKDMDPQTVM 167 Query: 268 FFNTYVHFQGKMRGFSQ--LTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRV 325 ++V+F+G + T EF+VD T+V VPM+ G F + D + + +V R+ Sbjct: 168 LLASFVYFKGSWEKPFEAEHTEEREFFVDAETTVKVPMMYQMGRFDFYFDEELSCTVVRL 227 Query: 326 PLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQD 385 S T L+ P + ++E + + W + R + L P+ I GSY + + Sbjct: 228 HYNGSATAFLVLP-AKGKMKQLEQTLDKETIQKWSDHLFQRFMNLYFPKFSISGSYEISN 286 Query: 386 LLAQAKLSTLLGAEANLGKM-GDTNPRVGEVLNSILLELQA-GEEEQPTESAQQPGSPEV 443 L + + + +A+L + G + +V +V++ L++ G E + + Sbjct: 287 TLRKMGIVDVFTNQADLSGITGSPDLKVSKVVHKASLDVDEKGTEAAAATAVEIMPISFP 346 Query: 444 LDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + S PFL I++RD+ + F+G++ NP Sbjct: 347 PTIEFSHPFLMLIFDRDTNSTLFIGKIVNP 376 >6F02-A nrPDB Length = 389 Score = 347 bits (891), Expect = 5e-96, Method: Composition-based stats. Identities = 81/391 (20%), Positives = 143/391 (36%), Gaps = 29/391 (7%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 ++A FR Y +++ + SP ++ LG+ + SQ+ LG Sbjct: 6 KIAPANADFAFRFYYLIA-SETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 64 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 + E S D H+ L L L LF + L+ F+ Sbjct: 65 LTE---LSESDVHRGFQHLLHTLNL--------PGHGLETRVGSALFLSHNLKFLAKFLN 113 Query: 216 S-LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVH 274 + + +F + D V Q IN V+ T K+ + + D + Y++ Sbjct: 114 DTMAVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIY 170 Query: 275 FQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQ-HWSDAQNNFSVTRVPLGESV 331 F+ S T +F+VD +T+V VPM+ + D SV R+ Sbjct: 171 FKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA 230 Query: 332 TLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPR----AIRLTLPQLEIRGSYNLQDLL 387 T+ I P + +E ++ + W R + L LP+ I GSY L +L Sbjct: 231 TVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQIL 289 Query: 388 AQAKLSTLLGAEANLGKMGDTN-PRVGEVLNSILLELQ--AGEEEQPTESAQQPGSPEVL 444 + + L A+L + + + L++ E T A + S + Sbjct: 290 PRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTN 349 Query: 445 D--VTLSSPFLFAIYERDSGALHFLGRVDNP 473 + + PFL I+ + ++ FLG+V +P Sbjct: 350 RHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 380 >3DY0-A nrPDB Length = 336 Score = 338 bits (866), Expect = 4e-93, Method: Composition-based stats. Identities = 80/346 (23%), Positives = 144/346 (41%), Gaps = 24/346 (6%) Query: 103 FMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCT 162 F +Y+ L+ + + SP ++ +L LG+ T Q+ LG+ +++ Sbjct: 11 DFTFDLYRALA-SAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEK 69 Query: 163 SRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTP 222 G Q LL L S LFT + L+ FV ++ Sbjct: 70 ELHRG---------FQQLLQELNQPRDGFQL--SLGNALFTDLVVDLQDTFVSAMKTLYL 118 Query: 223 A-IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRG 281 A FP + D A ++IN +V T K+ L+ + +++ + Y+ F+ K Sbjct: 119 ADTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWET 175 Query: 282 FSQL--TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQ 339 T +F+V + T V VPM+S + + D + V VP + T L I P Sbjct: 176 SFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILP- 234 Query: 340 CASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAE 399 + +VE + + W+K R + L LP+ I GSY L+ +L +S + + Sbjct: 235 SEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSH 294 Query: 400 ANLGKMG-DTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 444 A+L + +N +V E+++ ++E+ +E T +A G+ Sbjct: 295 ADLSGISNHSNIQVSEMVHKAVVEV----DESGTRAAAATGTIFTF 336 >1JMJ-A nrPDB Length = 480 Score = 333 bits (853), Expect = 1e-91, Method: Composition-based stats. Identities = 71/387 (18%), Positives = 150/387 (38%), Gaps = 14/387 (3%) Query: 91 RQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQV 150 + R ++ ++ F +Y++L + ++P + + LG T Q+ Sbjct: 101 KSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHS 160 Query: 151 LLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLK 210 +L + +S+ + + + + L + +V L+ + Sbjct: 161 ILHFKDF-VNASSKYEITTIHNLFRKLTHRLFRRN-----FGYTLRSVNDLYIQKQFPIL 214 Query: 211 QPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFN 270 F + + A + D S DP ++ N + +T + LE + + + Sbjct: 215 LDFKTKVREYYFAE-AQIADFS-DPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMIL 271 Query: 271 TYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLG 328 ++F+G + ++T H F ++ V V M+ GNF +D + + + ++ Sbjct: 272 NCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYV 331 Query: 329 ESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLA 388 +++L++ P S + +E + W K+ R + LP+ ++ +YNL + L Sbjct: 332 GGISMLIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLK 391 Query: 389 QAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQ--PTESAQQPGSPEVLDV 446 + L N+ + D + + + + + T P S +V Sbjct: 392 LMGIRMLFDKNGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV-RF 450 Query: 447 TLSSPFLFAIYERDSGALHFLGRVDNP 473 T+ PFLF IYE + L F+GRV NP Sbjct: 451 TVDRPFLFLIYEHRTSCLLFMGRVANP 477 >4AJT-A nrPDB Length = 427 Score = 331 bits (849), Expect = 4e-91, Method: Composition-based stats. Identities = 85/391 (21%), Positives = 157/391 (40%), Gaps = 28/391 (7%) Query: 92 QRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVL 151 + + Q++ + GF + + +S + SP L +V+ LG+ T Q++ Sbjct: 53 RASQQLSNETSSFGFNLLRKISMRH--DGNVIFSPFGLSVAMVNLMLGTKGETKVQIENG 110 Query: 152 LGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQ 211 L + S+ + + V + SS L S F +K+ Sbjct: 111 LNL-----QALSQAGPLILPALFKKV------KETFSSNRDLGLSQGSFAFIHKDFDIKE 159 Query: 212 PFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNT 271 + + + S++ + A IN + T K+ + ++ ++ L Sbjct: 160 TYFNLSKKYFDIEY-VSINF-QNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVD 217 Query: 272 YVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGE 329 YV F+GK T F +D ++ VPM+ GNF D + + ++P Sbjct: 218 YVLFKGKWLTPFDPSFTEADTFHLDKYRAIKVPMMYREGNFTSTFDKKFRCHILKLPYQG 277 Query: 330 SVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQ 389 + T+L++ + D +E + TW++N R + + P+ ++ Y + +LL Q Sbjct: 278 NATMLVVLMEKTGDYLALEDYLTVDLVETWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQ 337 Query: 390 AKLSTLLGAEANLGKMG--DTNPRVGEVLNSILLELQAGEEEQPTESAQQPGS-----PE 442 + L A+L ++ N +V VL +LE+ +E+ TE+ S Sbjct: 338 MGIRRLFSTSADLSELSAMARNLQVSRVLQQSVLEV----DERGTEAVSGTLSEIIAYSM 393 Query: 443 VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + ++ PF F IYE S L FLGRV NP Sbjct: 394 PPAIKVNRPFHFIIYEEMSRMLLFLGRVVNP 424 >3NDA-A nrPDB Length = 377 Score = 331 bits (848), Expect = 5e-91, Method: Composition-based stats. Identities = 67/386 (17%), Positives = 141/386 (36%), Gaps = 22/386 (5%) Query: 95 AQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGV 154 A++ N G R+ + L G SP ++ + + G+ T +L LG Sbjct: 5 AKLTKANNRFGLRLLRALPS--GPEKNVFFSPYSVSTAMGMAFAGARGQTQQELSQGLGF 62 Query: 155 PVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV 214 + LD + T+ S+ + L L + Sbjct: 63 SDVDLTDAGVLDAYTHH-----------TERLKSTPSNSTLDVANAAAIQRTLALLNSYE 111 Query: 215 ESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL-EGVSTDSTLFFNTYV 273 +L A +D + +P A +N +V+ T K+ E + D+ L + Sbjct: 112 SALQSSFGAEL-HKVDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAI 170 Query: 274 HFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGE-S 330 +F+G+ + T +F+ T V V + ++ V +P Sbjct: 171 YFKGEWNTAFVKEHTEKRQFFNGGVTPVEVDTMRLEARIKYRFFDDLQVEVVELPYRGLD 230 Query: 331 VTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQA 390 T+ ++ P+ + ++ ++ + F ++ + R I + LP+ ++ Y+L+ L Sbjct: 231 YTMAILLPKENTGVEGLKQNLTIDRFQNYLSDLRERKITVLLPKFKLETKYSLKAPLQSL 290 Query: 391 KLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQP----GSPEVLDV 446 + + + A+L + D + RV V + ++E+ + PE + Sbjct: 291 GIKQIFESGADLSGINDGSLRVSAVEHKAVVEVNEEGTVAAATTGVVIVPYSLGPEPVVF 350 Query: 447 TLSSPFLFAIYERDSGALHFLGRVDN 472 + PFLF I + + F+G+V+ Sbjct: 351 RVDHPFLFFIRNTRTDDIFFVGQVNK 376 >4GA7-A nrPDB Length = 389 Score = 325 bits (833), Expect = 3e-89, Method: Composition-based stats. Identities = 78/394 (19%), Positives = 151/394 (38%), Gaps = 33/394 (8%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 Q++ ++ LSE A +SP ++ + +LG+ TA+QL Sbjct: 13 QLSSANTRFALDLFLALSEN-NPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 71 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 E +V + Q++ + +G S + L+ F+ Sbjct: 72 TVE----------EVHSRFQSLNADINKRGAS-----YILKLANRLYGEKTYNFLPEFLV 116 Query: 216 SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTYV 273 S A S+D A + IN++V+ T K+ L V + L + Sbjct: 117 STQKTYGADLA-SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAI 175 Query: 274 HFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GES 330 +F+G + + T F ++ +V M+ F + V +P GE Sbjct: 176 YFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEE 235 Query: 331 VTLLLIQP----QCASDLDRVEVLVFQHDFLTWIK--NPPPRAIRLTLPQLEIRGSYNLQ 384 ++++++ P ++ L ++E + W K N + ++LP+ ++ SY L Sbjct: 236 LSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLN 295 Query: 385 DLLAQAKLSTLL-GAEANLGKM-GDTNPRVGEVLNSILLELQAGEEEQPTESAQQP---G 439 LA+ + L ++A+L M G + + ++++ +E+ E +A Sbjct: 296 SDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCM 355 Query: 440 SPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + T PFLF I SG++ FLGR +P Sbjct: 356 DDPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 389 >4DY0-A nrPDB Length = 379 Score = 323 bits (827), Expect = 1e-88, Method: Composition-based stats. Identities = 74/391 (18%), Positives = 158/391 (40%), Gaps = 33/391 (8%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 + + + G +++ + ++R V+SP + L LG+ T QL +++ Sbjct: 8 LEELGSNTGIQVFNQIVKSR-PHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVM---- 62 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 R + V L+ + +V++ + + +F ++ PFV Sbjct: 63 -------RYGVNGVGKILKKINKAIVSKKNKD-----IVTVANAVFVKNASEIEVPFVTR 110 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTD-STLFFNTYV 273 R+++ DP A IN +V+ T ++ L + + L V Sbjct: 111 NKDVFQCEV-RNVNFE-DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAV 168 Query: 274 HFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDA---QNNFSVTRVPL- 327 +F+G + + T F + S VPML+ F+ S + ++ +P Sbjct: 169 YFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYH 228 Query: 328 GESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDL 386 GES+++L+ P + ++ L + + +W+ P+ +++ LP+ +L++ Sbjct: 229 GESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEP 288 Query: 387 LAQAKLSTLL-GAEANLGKM--GDTNPRVGEVLNSILLEL-QAGEEEQPTESAQQPGSPE 442 L ++ + ++AN K+ G N V +L +E+ + G + +A Sbjct: 289 LKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSS 348 Query: 443 VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + PFLF I +GA+ F+G+++ P Sbjct: 349 PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 379 >1UHG-A nrPDB Length = 385 Score = 320 bits (820), Expect = 9e-88, Method: Composition-based stats. Identities = 69/392 (17%), Positives = 146/392 (37%), Gaps = 20/392 (5%) Query: 95 AQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGV 154 + + F ++K L + P A+ L YLG+ D T +Q+ ++ Sbjct: 1 GSIGAASMEFCFDVFKEL-KVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRF 59 Query: 155 PVKEGDCTSRL----DGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLK 210 G S V ++L+ + + S S L+ + Sbjct: 60 DKLPGFGDSIEAQCGTSVNVHSSLRDILNQITKPNDVYS-----FSLASRLYAEERYPIL 114 Query: 211 QPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLP--LEGVSTDSTLF 268 +++ + ++ T A + IN +V++ T + V + + + Sbjct: 115 PEYLQCVKELYRGGL-EPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMV 173 Query: 269 FNTYVHFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVP 326 + F+G + T F V S V M+ G F+ S A + +P Sbjct: 174 LVNAIVFKGLWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKILELP 233 Query: 327 LG-ESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKN--PPPRAIRLTLPQLEIRGSYNL 383 ++++L++ P S L+++E ++ W + R I++ LP++++ YNL Sbjct: 234 FASGTMSMLVLLPDEVSGLEQLESIINFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNL 293 Query: 384 QDLLAQAKLSTLLGAEANLGKMGD-TNPRVGEVLNSILLELQAGEEE-QPTESAQQPGSP 441 +L ++ + + ANL + + ++ + +++ E+ E + A + Sbjct: 294 TSVLMAMGITDVFSSSANLSGISSAESLKISQAVHAAHAEINEAGREVVGSAEAGVDAAS 353 Query: 442 EVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + PFLF I + A+ F GR +P Sbjct: 354 VSEEFRADHPFLFCIKHIATNAVLFFGRCVSP 385 >6F4U-A nrPDB Length = 341 Score = 317 bits (812), Expect = 7e-87, Method: Composition-based stats. Identities = 68/338 (20%), Positives = 120/338 (35%), Gaps = 25/338 (7%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 ++A FR Y +++ + SP ++ LG+ + SQ+ LG Sbjct: 4 KIAPANADFAFRFYYLIA-SETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 62 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 + E S D H+ L L L LF + L+ F+ Sbjct: 63 LTE---LSESDVHRGFQHLLHTLNL--------PGHGLETRVGSALFLSHNLKFLAKFLN 111 Query: 216 S-LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVH 274 + + +F + D V Q IN V+ T K+ + + D + Y++ Sbjct: 112 DTMAVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIY 168 Query: 275 FQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQ-HWSDAQNNFSVTRVPLGESV 331 F+ S T +F+VD +T+V VPM+ + D SV R+ Sbjct: 169 FKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA 228 Query: 332 TLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPR----AIRLTLPQLEIRGSYNLQDLL 387 T+ I P + +E ++ + W R + L LP+ I GSY L +L Sbjct: 229 TVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQIL 287 Query: 388 AQAKLSTLLGAEANLGKMGDTN-PRVGEVLNSILLELQ 424 + + L A+L + + + L++ Sbjct: 288 PRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVD 325 >1QMB-A nrPDB Length = 326 Score = 317 bits (811), Expect = 1e-86, Method: Composition-based stats. Identities = 76/339 (22%), Positives = 142/339 (41%), Gaps = 26/339 (7%) Query: 104 MGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTS 163 F +Y+ L+ ++ SP ++ LG+ T ++ L + E + Sbjct: 9 FAFSLYRQLA--HQSSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAA 66 Query: 164 RLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFT-P 222 +G Q LL T SQ L +T GLF + GL+L F+E + Sbjct: 67 IHEG---------FQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHS 115 Query: 223 AIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM--R 280 F + D A ++IN +V+ T K+ ++ + D+ Y+ F+GK Sbjct: 116 EAFTVNF---GDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERP 172 Query: 281 GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQC 340 + T +F VD T+V VPM+ G F + + V + + T + P Sbjct: 173 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPD- 231 Query: 341 ASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEA 400 L +E + +++N R+ L LP+L I G+Y+L+ +L Q ++ + A Sbjct: 232 EGKLQHLENELTHDIITKFLEN-DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGA 290 Query: 401 NLGKMGDTNP-RVGEVLNSILLELQAGEEEQPTESAQQP 438 +L + + P ++ + ++ +L + +E+ TE+A Sbjct: 291 DLSGVTEEAPLKLSKAVHKAVLTI----DEKGTEAAGAM 325 >3ZHA-A nrPDB Length = 392 Score = 316 bits (810), Expect = 1e-86, Method: Composition-based stats. Identities = 81/389 (20%), Positives = 165/389 (42%), Gaps = 24/389 (6%) Query: 93 RAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLL 152 +AA +A + + F +Y+ +++ + V +LSP + +L LG TASQ + +L Sbjct: 5 KAATLAERSAGLAFSLYQAMAKDQAV-ENILLSPVVVASSLGLVSLGGKATTASQAKAVL 63 Query: 153 GVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQP 212 +L +V L G L+ +S+ + L+ + + Sbjct: 64 --------SAEQLRDEEVHAGL----GELLRSLSNSTARNVTWKLGSRLYGPSSVSFAED 111 Query: 213 FVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTY 272 FV S + ++ D A Q IN + T K+ + V Sbjct: 112 FVRSSKQHYNCEHSK-INF-RDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNA 169 Query: 273 VHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGES 330 + F+ + ++ F V S +V V M+ TG + ++ D + + +PL Sbjct: 170 MFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQIVEMPLAHK 229 Query: 331 VT-LLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQ 389 ++ L+++ P L+R+E L+ + W+ +A+ ++LP+ + +++LQ LA Sbjct: 230 LSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAG 289 Query: 390 AKLSTLLG-AEANLGKM-GDTNPRVGEVLNSILLEL--QAGEEEQPTESAQQPGSPEVLD 445 L+ + +A+L +M G + + V ++ E + +Q ++ SP++ Sbjct: 290 LGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKL-- 347 Query: 446 VTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 PF+F + + SG+L F+GR+ P+ Sbjct: 348 FYADHPFIFLVRDTQSGSLLFIGRLVRPK 376 >2R9Y-A nrPDB Length = 430 Score = 312 bits (800), Expect = 2e-85, Method: Composition-based stats. Identities = 88/391 (22%), Positives = 143/391 (36%), Gaps = 33/391 (8%) Query: 87 EAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTAS 146 AE+ +R AQ M F + S + S VLSP ++ L LG+ + T Sbjct: 14 TAEETRRLAQAMMAFTTDLFSLVAQTSTS----SNLVLSPLSVALALSHLALGAQNQTLH 69 Query: 147 QLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPG 206 L +L + G C L H Q L P ++ G Sbjct: 70 SLHRVLHMN--TGSCLPHLLSH-------FYQNL----------GPGTIRLAARIYLQKG 110 Query: 207 LRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDST 266 +K F+E A P L + LA IN++V+ T K+ L + + Sbjct: 111 FPIKDDFLEQSERLFGAK-PVKLTGKQEEDLA--NINQWVKEATEGKIEDFLSELPDSTV 167 Query: 267 LFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSD-AQNNFSVT 323 L +HF G + LT F +D +VSV M+ W Q V Sbjct: 168 LLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVA 227 Query: 324 RVPLGESVTLLLIQPQC-ASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYN 382 P +++ +++ P ++ V + + + R ++ LP+L ++ + Sbjct: 228 HFPFKNNMSFVVVMPTYFEWNVSEVLANLTWDTL--YHPSLQERPTKVWLPKLHLQQQLD 285 Query: 383 LQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPE 442 L L+Q L L +L + + N V V + +EL E ++ Sbjct: 286 LVATLSQLGLQELF-QGPDLRGISEQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMS 344 Query: 443 VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + T++ PFLF I E G F+G V NP Sbjct: 345 LSSFTVNRPFLFFIMEDTIGVPLFVGSVRNP 375 >4P0F-A nrPDB Length = 393 Score = 312 bits (799), Expect = 2e-85, Method: Composition-based stats. Identities = 76/391 (19%), Positives = 148/391 (37%), Gaps = 34/391 (8%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 + A +Y LS + V SP ++ LG+ + TA+QL LG+ Sbjct: 9 EFARRLALFSINVYGKLSG-QKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLA 67 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 + + + H+VL A Q Q L +F G +L+Q F + Sbjct: 68 SSDPEQIAH-SFHQVLAAYQDSQIL---------------RIANKIFVMDGYQLRQEFDQ 111 Query: 216 SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFNTYV 273 L + +S+D S + V AA IN +V+ T + + + ++++S L + Sbjct: 112 LLSKQFLSA-AQSVDFSKN-VQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAI 169 Query: 274 HFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGE-S 330 HF+G + LT F +D +V VPM+S F++ + +P + Sbjct: 170 HFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSD 229 Query: 331 VTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQA 390 +++L++ P + L +E + ++ + L LP+ + L ++ + Sbjct: 230 LSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKL 289 Query: 391 KLSTLLGAEANLGKM--GDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSP------- 441 +S + +A GKM +V +++ +E+ E + Sbjct: 290 GMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPE 349 Query: 442 EVLDVTLSSPFLFAIYERDSGALHFLGRVDN 472 E ++ PF + + + F G V Sbjct: 350 EPIEFFADHPFTYVLVHQK-DLPLFWGSVVR 379 >4KDS-A nrPDB Length = 386 Score = 312 bits (798), Expect = 3e-85, Method: Composition-based stats. Identities = 89/391 (22%), Positives = 159/391 (40%), Gaps = 32/391 (8%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 + G R++ +++ S SP + L LG+ T L LG + Sbjct: 15 LQEKQTDFGMRVFSQVAQN-SKGSNLAFSPYGVATILAMAQLGAGGNTLKTLNAKLGFSL 73 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 +E + Q LL S L G+ + L++ F Sbjct: 74 QE-------------RGMARQQRLLQRDISSEEGVEL----ASGVMVERKMALEKGFRRG 116 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTYVH 274 LG A P LD S P A IN +V T + L ++ ++ + +H Sbjct: 117 LGKAFQAS-PHQLDFSR-PDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALH 174 Query: 275 FQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNN---FSVTRVPL-G 328 FQG + ++T F N +SV VPM+ T F++ + + V VP G Sbjct: 175 FQGLWKVPFDPKMTEERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPYEG 234 Query: 329 ESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLL 387 ES+++LL+ P + + + + + W + +L LP+ + L+ +L Sbjct: 235 ESLSMLLVSPFEPETPVSSLSSELTTQRLQQWRQEMRSVKRQLVLPRFTLDSEVELKSIL 294 Query: 388 AQAKLSTLLG-AEANLGKMGDTNPR-VGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVL 444 Q L + A+A+ ++ P V +VL + +E+ + G + +A V Sbjct: 295 IQMGLGDMFNLAKADFTRITTEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMAVE 354 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNPQN 475 ++T++ PFLF I+ + +GA+ F+G+V+ PQ Sbjct: 355 EITMNRPFLFLIHHKSTGAVLFMGQVNQPQQ 385 >4AJU-A nrPDB Length = 387 Score = 309 bits (791), Expect = 2e-84, Method: Composition-based stats. Identities = 69/350 (19%), Positives = 136/350 (38%), Gaps = 25/350 (7%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 Q+A + GF + + +S V SP + + LG+ PT +Q++ L + Sbjct: 53 QLAKETSNFGFSLLRKISMRH--DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 110 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 + L +GL T S L + F +K+ F Sbjct: 111 ALKPTKPGLLPS--------LFKGLRETL---SRNLELGLTQGSFAFIHKDFDVKETFFN 159 Query: 216 SLGPFTP-AIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVH 274 + P + + A + +N ++ T K+ + ++ ++ L Y+ Sbjct: 160 LSKRYFDTECVPMNF---RNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYIL 216 Query: 275 FQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVT 332 F+GK T + F +D ++ VPM+ G G F D V ++P + T Sbjct: 217 FKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNAT 276 Query: 333 LLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKL 392 +L++ + D +E + TW++N R + + P+ ++ Y + +LL Q + Sbjct: 277 MLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGI 336 Query: 393 STLLGAEANLGKMGD--TNPRVGEVLNSILLELQAGEEEQPTESAQQPGS 440 + A+L ++ N +V VL ++E+ +E+ TE+ S Sbjct: 337 RRIFSPFADLSELSATGRNLQVSRVLQRTVIEV----DERGTEAVAGILS 382 >5NCS-A nrPDB Length = 375 Score = 303 bits (777), Expect = 8e-83, Method: Composition-based stats. Identities = 64/378 (16%), Positives = 142/378 (37%), Gaps = 28/378 (7%) Query: 102 NFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDC 161 N F + + + + +SP ++ L G+ TA +++ L + Sbjct: 12 NAFAFDLLQ-TTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRETGYTMED 70 Query: 162 TSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFT 221 + H + AL V ++ G +K+PF+ + Sbjct: 71 INEY-SHSLREALLKV------------DPSTTIGMANSIWYKQGELVKEPFILANRTHY 117 Query: 222 PAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM-- 279 A +++D S+ L A IN + T K+ L+ + ++ ++ V+F+G Sbjct: 118 DAEV-KAVDFSSPATLPA--INGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVT 174 Query: 280 RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESV-TLLLIQP 338 + T F + T+ V M++ F + +D + G +++++ P Sbjct: 175 QFKKSDTKRAPFRKADGTTQEVNMMAQKSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLP 232 Query: 339 QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNL-QDLLAQAKLSTLLG 397 V + + IK P + L +P+ + Y L + +L + ++ Sbjct: 233 NEGQTTRDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFT 292 Query: 398 AEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESA---QQPGSPE--VLDVTLSSPF 452 A+ + D + V++ +++ E +A + SP ++ ++ PF Sbjct: 293 ETADFPGITDAAIFISRVIHKTFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFHINKPF 352 Query: 453 LFAIYERDSGALHFLGRV 470 +FAI E+ +G + F+G + Sbjct: 353 VFAIREKSTGVILFIGEI 370 >4DTE-A nrPDB Length = 374 Score = 298 bits (764), Expect = 2e-81, Method: Composition-based stats. Identities = 84/386 (21%), Positives = 157/386 (40%), Gaps = 32/386 (8%) Query: 102 NFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDC 161 G +++ ++ LSP + L +G+ T L +G ++E Sbjct: 8 TDFGLQVFAEAVQS-APDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQE--- 63 Query: 162 TSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFT 221 + +Q LL S + G+ + L++ F SL Sbjct: 64 ----------RGMPKLQRLLQRDLASEDGVEV----ASGVMVDRKIILEKVFRRSLSKAF 109 Query: 222 PAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNL-PLEGVSTD-STLFFNTYVHFQGKM 279 + P +D S P +A Q IN + T ++ GV ++ + L F +HF G Sbjct: 110 QS-VPHQIDFSQ-PEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVW 167 Query: 280 R--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHW---SDAQNNFSVTRVPL-GESVTL 333 + + T F N ++VSVPM++ T F + S ++ V +P GES+++ Sbjct: 168 KTPFDPRNTREQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISM 227 Query: 334 LLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKL 392 LL+ P + L + + W + + +L++P+ + +L+ L++ L Sbjct: 228 LLVTPFEKDVPLSALNKELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGL 287 Query: 393 STLLG-AEANLGKMGDTNPR-VGEVLNSILLEL-QAGEEEQPTESAQQPGSPEVLDVTLS 449 + + A+ ++ P V +VL + LE+ + G + +A V ++TL Sbjct: 288 GDIFSQSRADFSRITTEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITLD 347 Query: 450 SPFLFAIYERDSGALHFLGRVDNPQN 475 PF F I + +GAL F G++ PQ Sbjct: 348 RPFFFLIQHKPTGALLFSGQLTQPQE 373 >1IMV-A nrPDB Length = 398 Score = 296 bits (759), Expect = 9e-81, Method: Composition-based stats. Identities = 85/415 (20%), Positives = 171/415 (41%), Gaps = 25/415 (6%) Query: 65 AKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVL 124 + P + D E+ + + ++A + G+ +Y++ S + + +L Sbjct: 2 PASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRS-SMSPTTNVLL 60 Query: 125 SPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQ 184 SP ++ L + LG+ + T S + L D S D H L + + Q Sbjct: 61 SPLSVATALSALSLGADERTESIIHRALYY-----DLISSPDIHGTYKEL--LDTVTAPQ 113 Query: 185 GGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINR 244 + + LR+K FV P + R L+ +P L Q+IN Sbjct: 114 KN--------LKSASRIVFEKKLRIKSSFV---APLEKSYGTRPRVLTGNPRLDLQEINN 162 Query: 245 FVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVP 302 +VQA K+ + + + ++ HF+G+ + S+ T L +F++D +V VP Sbjct: 163 WVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVP 222 Query: 303 MLSG-TGNFQHWSDAQNNFSVTRVPLGESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWI 360 M+S ++ D+ + + ++PL S++++ P + +L +E + Sbjct: 223 MMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDID 282 Query: 361 KNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSIL 420 + LT+P+L++ + L + KL +L + + K+ ++ +V + Sbjct: 283 RELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITGKPIKLTQVEHRAG 341 Query: 421 LELQAGEEEQPTESAQQPGS-PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 E QP LD L+ PF+F + + D+GAL F+G++ +P+ Sbjct: 342 FEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPR 396 >2XN5-A nrPDB Length = 350 Score = 294 bits (753), Expect = 5e-80, Method: Composition-based stats. Identities = 61/347 (17%), Positives = 130/347 (37%), Gaps = 23/347 (6%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 +++ I F +Y+ + SP ++ LV G+ T +++ LG Sbjct: 10 KMSSINADFAFNLYRRFT-VETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFN 68 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 + + G Q L+ + + L LF L+ F+ Sbjct: 69 LTDTPMVEIQHG---------FQHLICSLNFPKKELELQ--IGNALFIGKHLKPLAKFLN 117 Query: 216 SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHF 275 + S D S + A Q+IN V+ T K+ ++ + ++ + Y+HF Sbjct: 118 DVKTLYETEVF-STDFS-NISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHF 175 Query: 276 QGKMRGFSQLTGLHE---FWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVT 332 + + + + F +D +T+V VPM+ + H D + N +V ++ ++ Sbjct: 176 KAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNAL 235 Query: 333 LLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKL 392 L + P+ ++ VE + W + + L +P+ I +Y+L L + + Sbjct: 236 ALFVLPK-EGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGI 294 Query: 393 STLLGAEANLGKMGDTN-PRVGEVLNSILLELQAGEEEQPTESAQQP 438 A+ + + N ++ + +L + E+ TE+A Sbjct: 295 QHAYSENADFSGLTEDNGLKLSNAAHKAVLHIG----EKGTEAAGAM 337 >1HLE-A nrPDB Length = 345 Score = 294 bits (752), Expect = 6e-80, Method: Composition-based stats. Identities = 63/342 (18%), Positives = 130/342 (38%), Gaps = 30/342 (8%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 Q++ +++ L+E+ +SP ++ L +LG+ TA+Q+ L Sbjct: 4 QLSTANTHFAVDLFRALNES-DPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFD 62 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 E D H +L A + P + L+ F+ Sbjct: 63 TVE-------DIHSRFQSLNA--------DINKPGAPYILKLANRLYGEKTYNFLADFLA 107 Query: 216 SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFNTYV 273 S A S+D P A ++IN +V+ T K+ L V + L + Sbjct: 108 STQKMYGAELA-SVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAI 166 Query: 274 HFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGE-S 330 +F+G + + T F ++ + +V M+ F + V +P Sbjct: 167 YFKGNWQQKFMKEATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIEDLKCRVLELPYQGKE 226 Query: 331 VTLLLIQP----QCASDLDRVEVLVFQHDFLTWIK--NPPPRAIRLTLPQLEIRGSYNLQ 384 ++++++ P ++ L+++E + W K N + + LP+ ++ SY+L Sbjct: 227 LSMIILLPDDIEDESTGLEKIEKQLTLDKLREWTKPENLYLAEVNVHLPRFKLEESYDLT 286 Query: 385 DLLAQAKLSTLLG-AEANLGKM-GDTNPRVGEVLNSILLELQ 424 LA+ + L +A+L M G + V ++++ ++L Sbjct: 287 SHLARLGVQDLFNRGKADLSGMSGARDLFVSKIIHKSFVDLN 328 >3F02-A nrPDB Length = 359 Score = 290 bits (742), Expect = 1e-78, Method: Composition-based stats. Identities = 60/354 (16%), Positives = 135/354 (38%), Gaps = 28/354 (7%) Query: 99 MIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKE 158 + MY L A G + SP ++ + LG+ T +++ +G Sbjct: 21 EAIADLSVNMYNRL-RATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDS-- 77 Query: 159 GDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLG 218 L + + L+ ++ ++ ++ + LF G + + F++ + Sbjct: 78 ------LKNGEEFSFLKEFSNMV-----TAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 126 Query: 219 PFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLE--GVSTDSTLFFNTYVHFQ 276 + A +D S + +A IN++V+ T + + + L V+F+ Sbjct: 127 KYFNAAVNH-VDFSQNVAVA-NYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFK 184 Query: 277 GKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNN------FSVTRVPL- 327 G + + T F D+ + V +PM+ G F + + + + V +P Sbjct: 185 GNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYE 244 Query: 328 GESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLL 387 G+ ++++L+ + L +E LV W + + + + LP+ + +L+D+L Sbjct: 245 GDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVL 304 Query: 388 AQAKLSTLLGAEANLGKMGD-TNPRVGEVLNSILLELQAGEEEQPTESAQQPGS 440 ++ + +ANL + D + + ++ LE+ E S S Sbjct: 305 KALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAIS 358 >1C5G-A nrPDB Length = 402 Score = 283 bits (723), Expect = 1e-76, Method: Composition-based stats. Identities = 74/389 (19%), Positives = 152/389 (39%), Gaps = 29/389 (7%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 VA +A+ G R+++ +++A V SP + L L + T Q+Q +G Sbjct: 31 VAHLASDFGVRVFQQVAQA-SKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF-- 87 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 ++D + AL+ + L+ ST +F L+L Q F+ Sbjct: 88 -------KIDDKGMAPALRHLYKELMGPWNKD-----EISTTDAIFVQRDLKLVQGFMPH 135 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLE--GVSTDSTLFFNTYVH 274 + + +D S + A IN +V+ T ++ L V + L ++ Sbjct: 136 FFRLFRSTV-KQVDFS-EVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALY 193 Query: 275 FQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNN---FSVTRVPL-G 328 F G+ + T F + ++VSVPM++ T F + + + + +P G Sbjct: 194 FNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHG 253 Query: 329 ESVTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLL 387 +++++ + P + L + ++ W N L LP+ + +L+ L Sbjct: 254 DTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPL 313 Query: 388 AQAKLSTLL-GAEANLGKMGDTNP-RVGEVLNSILLELQA-GEEEQPTESAQQPGSPEVL 444 ++ + +A+ + D P V + L + +E+ G + + Sbjct: 314 ENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPE 373 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNP 473 ++ + PFLF + +G + F+G+V P Sbjct: 374 EIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402 >2H4P-A nrPDB Length = 394 Score = 277 bits (708), Expect = 8e-75, Method: Composition-based stats. Identities = 58/379 (15%), Positives = 131/379 (34%), Gaps = 31/379 (8%) Query: 88 AEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQ 147 E QV+ ++ L+E SP ++ L YL + TA + Sbjct: 20 HELEISMEQVSASIGNFTVDLFNKLNET-NRDKNIFFSPWSISSALALTYLAAKGSTARE 78 Query: 148 LQVLLGVPVKEGDCTSR---------------LDGHKVLTALQAVQGLLVTQGGSSSQTP 192 + +L +S + + + LL + Sbjct: 79 MAEVLHFTEAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNYS 138 Query: 193 LLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGW 252 L + ++ L +++ + A P+ ++ T P + ++IN +V+ T Sbjct: 139 L--RSANRIYVEKTYALLPTYLQLSKKYYKAE-PQKVNFKTAPEQSRKEINTWVEKQTES 195 Query: 253 KMNLPL--EGVSTDSTLFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTG 308 K+ L + V + L ++F+ + + ++ T + F + + S V M+ Sbjct: 196 KIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRD 255 Query: 309 NFQHWSDAQNNFSVTRVPL-GESVTLLLIQPQC----ASDLDRVEVLVFQHDFLTW--IK 361 F + NF + +P +++ ++ P + L+++E + W K Sbjct: 256 TFPVLIMEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSK 315 Query: 362 NPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGD-TNPRVGEVLNSIL 420 + L LP+ + +L+D L ++T A+ M D + + +V++ Sbjct: 316 MMTETLVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSF 375 Query: 421 LELQAGEEEQPTESAQQPG 439 + + E +A Sbjct: 376 VAVDEKGTEAAAATAVIIS 394 >2H4Q-A nrPDB Length = 382 Score = 277 bits (708), Expect = 9e-75, Method: Composition-based stats. Identities = 57/356 (16%), Positives = 127/356 (35%), Gaps = 29/356 (8%) Query: 96 QVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVP 155 QV+ ++ L+E SP ++ L YL + TA ++ +L Sbjct: 44 QVSASIGNFTVDLFNKLNET-NRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFE 102 Query: 156 VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVE 215 E + LL + L + ++ L +++ Sbjct: 103 QAEN-------------IHSGFKELLTAFNKPRNNYSL--RSANRIYVEKTYALLPTYLQ 147 Query: 216 SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFNTYV 273 + A P+ ++ T P + ++IN +V+ T K+ L + V + L + Sbjct: 148 LSKKYYKAE-PQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAI 206 Query: 274 HFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPL-GES 330 +F+ + + ++ T + F + + S V M+ F + NF + +P Sbjct: 207 YFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRE 266 Query: 331 VTLLLIQPQC----ASDLDRVEVLVFQHDFLTW--IKNPPPRAIRLTLPQLEIRGSYNLQ 384 +++ ++ P + L+++E + W K + L LP+ + +L+ Sbjct: 267 LSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLR 326 Query: 385 DLLAQAKLSTLLGAEANLGKMGD-TNPRVGEVLNSILLELQAGEEEQPTESAQQPG 439 D L ++T A+ M D + + +V++ + + E +A Sbjct: 327 DTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGTEAVAATAVIIS 382 >2OAY-A nrPDB Length = 390 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 83/390 (21%), Positives = 162/390 (41%), Gaps = 40/390 (10%) Query: 95 AQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGV 154 A + ++Y S + V + SP ++ L LG+ + T + L+ +L Sbjct: 30 AVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY 89 Query: 155 PVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV 214 P K+ C V AL+ T+G +S V +F +P L ++ FV Sbjct: 90 P-KDFTC--------VHQALKGF----TTKGVTS---------VSQIFHSPDLAIRDTFV 127 Query: 215 ESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVH 274 + + PR L ++D L + IN +V T K++ L+ + +D+ L ++ Sbjct: 128 NASRTLYSSS-PRVLSNNSDANL--ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIY 184 Query: 275 FQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGN-FQHWSDAQNNFSVTRVPLGESV 331 K + + T + F ++ + VPM++ H+ D V ++ L ++ Sbjct: 185 LSAKWKTTFDPKKTRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNL 243 Query: 332 TLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIR---LTLPQLEIRGSYNLQDLL 387 +L+++ P L+ +E + F ++ + LTLP++++ S QD+L Sbjct: 244 SLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTS---QDML 300 Query: 388 AQAKLSTLLGAEANLGKMG---DTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 444 + + +L G D + +V + + +LEL E SA +L Sbjct: 301 SIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVART-LL 359 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVDNPQ 474 + PFLF ++++ F+GRV +P+ Sbjct: 360 VFEVQQPFLFMLWDQQHKFPVFMGRVYDPR 389 >3LW2-A nrPDB Length = 379 Score = 267 bits (683), Expect = 6e-72, Method: Composition-based stats. Identities = 71/393 (18%), Positives = 141/393 (35%), Gaps = 29/393 (7%) Query: 93 RAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLL 152 R + A A G ++++ + +A V SP + L + + T Q+Q + Sbjct: 4 RESHTAHQATDFGVKVFQQVVQA-SKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAM 62 Query: 153 GVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQP 212 G V E AL+ + L+ + ST +F L L Q Sbjct: 63 GFKVNEK---------GTAHALRQLSKELMGPWNKN-----EISTADAIFVQRDLELVQG 108 Query: 213 FVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFN 270 F+ + + +D S + A IN +V+ T +N L V + L Sbjct: 109 FMPHFFKLFQTMV-KQVDFS-EVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLV 166 Query: 271 TYVHFQGKMRGFS--QLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQ---NNFSVTRV 325 ++F G+ + T F + ++VSVPM++ + F + + V + Sbjct: 167 NALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVEL 226 Query: 326 PLGES-VTLLLIQP-QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNL 383 P +++ + P + L + ++ W N L LP+ + +L Sbjct: 227 PYQGDTLSMFIAAPFEKDVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDL 286 Query: 384 QDLLAQAKLSTLLGAE-ANLGKMGDTN-PRVGEVLNSILLELQA-GEEEQPTESAQQPGS 440 + L + + + A A+ + D V + L + +E+ G + + Sbjct: 287 RGPLEKLGMPDMFSATLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISAR 346 Query: 441 PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 ++ + FLF + + + F+G+V P Sbjct: 347 MAPTEMVIDRSFLFVVRHNPTETILFMGQVMEP 379 >5NCU-A nrPDB Length = 336 Score = 267 bits (682), Expect = 9e-72, Method: Composition-based stats. Identities = 53/341 (15%), Positives = 121/341 (35%), Gaps = 23/341 (6%) Query: 102 NFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDC 161 N F + + + + +SP ++ L G+ TA +++ L + Sbjct: 12 NAFAFDLLQ-TTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRETGYTMED 70 Query: 162 TSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFT 221 + H + AL V ++ G +K+PF+ + Sbjct: 71 INEY-SHSLREALLKV------------DPSTTIGMANSIWYKQGELVKEPFILANRTHY 117 Query: 222 PAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM-- 279 A +++D S+ L A IN + T K+ L+ + ++ ++ V+F+G Sbjct: 118 DAEV-KAVDFSSPATLPA--INGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVT 174 Query: 280 RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESV-TLLLIQP 338 + T F + T+ V M++ F + +D + G +++++ P Sbjct: 175 QFKKSDTKRAPFRKADGTTQEVNMMAQKSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLP 232 Query: 339 QCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNL-QDLLAQAKLSTLLG 397 V + + IK P + L +P+ + Y L + +L + ++ Sbjct: 233 NEGQTTRDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFT 292 Query: 398 AEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQP 438 A+ + D + V++ +++ E +A + Sbjct: 293 ETADFPGITDAAIFISRVIHKTFVQVDEEGTEAAAVTAVEM 333 >6CJ7-A nrPDB Length = 390 Score = 255 bits (652), Expect = 3e-68, Method: Composition-based stats. Identities = 72/393 (18%), Positives = 150/393 (38%), Gaps = 35/393 (8%) Query: 94 AAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLG 153 A + G ++K ++ + SP ++ L G+ T ++ L Sbjct: 10 AIHSGPASTSFGVNVFKQMATEQS--GNLAASPFSITILLAMLQQGAAGNTLDEITRALQ 67 Query: 154 VPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPF 213 + ++ + V + + + + T +F + L F Sbjct: 68 MTPEKSAEI-----------FKKVNEEIQKRNSRN-----ILKTANNVFLSENFNLNPQF 111 Query: 214 VE-SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLP--LEGVSTDSTLFFN 270 ++ F + P P LAAQ IN ++ + T K++ + +S ++ + Sbjct: 112 KRIAVNNFDSDLTPTYF---GKPALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMV 168 Query: 271 TYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLG 328 V+F+G Q T F ++ + F+ + V +P Sbjct: 169 NAVYFKGLWEIPFREQATQKRNFTLNGGEKKVASFMQTRRYFKAGTHKPAMAKVVVLPFE 228 Query: 329 -ESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLL 387 +L+++ P +S++D + + D +++ PP+ + L LP+ I+ NL+ +L Sbjct: 229 YNEYSLIVVLPLKSSNVDALLSSLSMEDVASFLD-LPPKDVALELPKFSIKADINLEPVL 287 Query: 388 AQAKLSTLLGAEA---NLGKMGDTNPRVGEVLNSILLELQA--GEEEQPTESAQQPGSPE 442 + +S++ +A NLG G +P+V L+S +L + G T A S + Sbjct: 288 NKMGVSSIFTQQAELYNLGSHGSLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYD 347 Query: 443 --VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 L + PFL +++ S F+ R+ +P Sbjct: 348 EPSLYFRANKPFLAILWDNRSSIPLFMARIMDP 380 >1JJO-C nrPDB Length = 261 Score = 244 bits (624), Expect = 5e-65, Method: Composition-based stats. Identities = 48/263 (18%), Positives = 103/263 (39%), Gaps = 14/263 (5%) Query: 190 QTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAV 249 + + LF G + + F++ L + A +D S + +A IN++V+ Sbjct: 1 ENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNH-VDFSQNVAVA-NSINKWVENY 58 Query: 250 TGWKMNLP--LEGVSTDSTLFFNTYVHFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLS 305 T + E + L V+F+G + + T F D+ + V +PM+ Sbjct: 59 TNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMY 118 Query: 306 GTGNFQHWSDAQNN------FSVTRVPL-GESVTLLLIQPQCASDLDRVEVLVFQHDFLT 358 G F + + + + V +P G+ ++++L + L +E L+ Sbjct: 119 QQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEE 178 Query: 359 WIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGD-TNPRVGEVLN 417 W + + + + LP+ + +L+D+L ++ + +ANL M D + + ++ Sbjct: 179 WANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKELFLSKAVH 238 Query: 418 SILLELQAGEEEQPTESAQQPGS 440 +E+ E S S Sbjct: 239 KSCIEVNEEGSEAAAASGMIAIS 261 >1XQJ-A nrPDB Length = 389 Score = 235 bits (599), Expect = 4e-62, Method: Composition-based stats. Identities = 60/390 (15%), Positives = 136/390 (34%), Gaps = 31/390 (7%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 + + + ++K LSE + + SP AL +L +G+ TA+++ +L Sbjct: 18 LQLANSAFAVDLFKQLSE-KEPLGNVLFSPIALSTSLSLAQVGAKGDTANEIGQVLHFE- 75 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 V Q + SS L + L+ L L F+ S Sbjct: 76 ------------NVKDVPFGFQTVTSDVNKLSSFYSL--KLIKRLYVDKSLNLSTEFISS 121 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTYVH 274 ++D +IN ++ +T L V+ + + + Sbjct: 122 TKRPYAKEL-ETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAY 180 Query: 275 FQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGES-V 331 F GK + T F V+ + + V M++ F + N + +P + Sbjct: 181 FVGKWMKKFSESETKESPFRVNKTDTKPVQMMNMEATFSMGNIDSINSKIIELPFQNKHL 240 Query: 332 TLLLIQP----QCASDLDRVEVLVFQHDFLTWI--KNPPPRAIRLTLPQLEIRGSYNLQD 385 ++ ++ P ++ L+++E + W ++L++P+ ++ + + Sbjct: 241 SMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKA 300 Query: 386 LLAQAKLSTLLGAE-ANLGKMGDTN-PRVGEVLNSILLELQAGEEEQPTESAQQPGSPEV 443 L L + + ++ M +T + V++ + LE+ + E Sbjct: 301 SLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVSLEITEDGGDS-IEVPGARILQHK 359 Query: 444 LDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 ++ PF++ I + + F G+ +P Sbjct: 360 DELNADHPFIYIIRHNKTRNIIFFGKFSSP 389 >1K9O-I nrPDB Length = 378 Score = 224 bits (572), Expect = 5e-59, Method: Composition-based stats. Identities = 63/399 (15%), Positives = 140/399 (35%), Gaps = 35/399 (8%) Query: 88 AEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQ 147 A + + + +M+ + +A VLS ++ L L S+ + + Sbjct: 2 AGETDLQKILRESNDQFTAQMFSEVVKA-NPGQNVVLSAFSVLPPLGQLALASVGESHDE 60 Query: 148 LQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGL 207 L L +P D ++ + A++ V ++ A GL Sbjct: 61 LLRALALPNDNVTKDVFADLNRGVRAVKGVD----------------LKMASKIYVAKGL 104 Query: 208 RLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLP--LEGVSTDS 265 L F + +++D V AA IN++V+ T ++ + + + Sbjct: 105 ELNDDFAAVSRDVFGSEV-QNVDFVK-SVEAAGAINKWVEDQTNNRIKNLVDPDALDETT 162 Query: 266 TLFFNTYVHFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVT 323 ++F+G + + T +F V ++ VP + G + ++ + + + Sbjct: 163 RSVLVNAIYFKGSWKDKFVKERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMI 222 Query: 324 RVPLGES-VTLLLIQPQCASDLDRVEVLVF-QHDFLTWIKNPPPRAIRLTLPQLEIRGSY 381 + ++++I P + +E + + + +TLP+ +I + Sbjct: 223 EMSYEGDQASMIIILPNQVDGITALEQKLKDPKALSRAEERLYNTEVEITLPKFKIETTT 282 Query: 382 NLQDLLAQAKLSTLLGAEA----NLGKMGDTNPRVGEVLNSILL--ELQAGEEEQPTESA 435 +L+++L+ + L A NL K + V + + + E Sbjct: 283 DLKEVLSNMNIKKLFTPGAARLENLLK-TKESLTVDAAIQKAFIEVNEEGAEAAAANAFG 341 Query: 436 QQPGSPEV-LDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 P S + +V + PF F + + G F G+V P Sbjct: 342 IVPKSLILYPEVHIDRPFYFEL--KIDGIPMFNGKVIEP 378 >1SEK-A nrPDB Length = 378 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 61/399 (15%), Positives = 140/399 (35%), Gaps = 35/399 (8%) Query: 88 AEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQ 147 A + + + +M+ + +A VLS ++ L L S+ + + Sbjct: 2 AGETDLQKILRESNDQFTAQMFSEVVKA-NPGQNVVLSAFSVLPPLGQLALASVGESHDE 60 Query: 148 LQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGL 207 L L +P D ++ + A++ V ++ A GL Sbjct: 61 LLRALALPNDNVTKDVFADLNRGVRAVKGVD----------------LKMASKIYVAKGL 104 Query: 208 RLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLP--LEGVSTDS 265 L F + +++D V AA IN++V+ T ++ + + + Sbjct: 105 ELNDDFAAVSRDVFGSEV-QNVDFVK-SVEAAGAINKWVEDQTNNRIKNLVDPDALDETT 162 Query: 266 TLFFNTYVHFQGKMR--GFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVT 323 ++F+G + + T +F V ++ VP + G + ++ + + + Sbjct: 163 RSVLVNAIYFKGSWKDKFNKERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMI 222 Query: 324 RVPLGES-VTLLLIQPQCASDLDRVEVLVF-QHDFLTWIKNPPPRAIRLTLPQLEIRGSY 381 + ++++I P + +E + + + + LP+ +I + Sbjct: 223 EMSYEGDQASMIIILPNQVDGITALEQKLKDPKALSRAEERLYNTEVEIYLPKFKIETTT 282 Query: 382 NLQDLLAQAKLSTLLGAEA----NLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQ 437 +L+++L+ + L A NL K + V + +E+ E +A + Sbjct: 283 DLKEVLSNMNIKKLFTPGAARLENLLK-TKESLYVDAAIQKAFIEVNEEGAEAAAANAFK 341 Query: 438 PGSPE---VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + V V ++ PF F++ + F G P Sbjct: 342 ITTYSFHFVPKVEINKPFFFSLKYNRNS--MFSGVCVQP 378 >3LE2-A nrPDB Length = 393 Score = 214 bits (545), Expect = 6e-56, Method: Composition-based stats. Identities = 67/400 (16%), Positives = 134/400 (33%), Gaps = 49/400 (12%) Query: 102 NFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDC 161 N + + K + S + SP ++ L GS T Q+ L + Sbjct: 13 NQVSMNLAKHVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSSTD--- 69 Query: 162 TSRLDGHKVLTALQAVQGLLVT--QGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGP 219 L + +V+ S+ S G + L K F + L Sbjct: 70 -----------QLNSFSSEIVSAVLADGSANGGPKLSVANGAWIDKSLSFKPSFKQLLED 118 Query: 220 FTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTYVHFQG 277 A ++ D + V ++N + + T + L + + L F ++F+G Sbjct: 119 SYKAASNQA-DFQSKAVEVIAEVNSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKG 177 Query: 278 KM--RGFSQLTGLHEFWVDNSTSVSVPML-SGTGNFQHWSDAQNNFSVTRVPL-----GE 329 + LT EF + + V+ P + S + D F V +P Sbjct: 178 TWNEKFDESLTQEGEFHLLDGNKVTAPFMTSKKKQYVSAYDG---FKVLGLPYLQGQDKR 234 Query: 330 SVTLLLIQPQCASDLDRVEVLV--FQHDFLTWIKNPPPRAIRLT---LPQLEIRGSYNLQ 384 ++ P + L + + + P R +++ +P+ + ++ Sbjct: 235 QFSMYFYLPDANNGLSDLLDKIVSTPGFLD---NHIPRRQVKVREFKIPKFKFSFGFDAS 291 Query: 385 DLLAQAKLSTLLGAEANLGKMGDT-----NPRVGEVLNSILLELQAGEEEQPTESAQQ-- 437 ++L L++ E L +M ++ N V + + +E+ E SA Sbjct: 292 NVLKGLGLTSPFSGEEGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIK 351 Query: 438 ----PGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 + +D PFL + E +G + F+G+V +P Sbjct: 352 LRGLLMEEDEIDFVADHPFLLVVTENITGVVLFIGQVVDP 391 >1C8O-A nrPDB Length = 300 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 63/337 (18%), Positives = 135/337 (40%), Gaps = 44/337 (13%) Query: 107 RMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLD 166 +++ ++ + +SPP++ L Y G+ TA QL Sbjct: 2 DIFREIASSMK-GENVFISPPSISSVLTILYYGANGSTAEQLSK---------------- 44 Query: 167 GHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFP 226 V + ++ + ++ ++ K F+ +G Sbjct: 45 --------------YVEKEADKNKDDISFKSMNKVYGRYSAVFKDSFLRKIGDNF----- 85 Query: 227 RSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG-VSTDSTLFFNTYVHFQGKM--RGFS 283 +++D + IN+ V T K+N L+ +S D++L + V+F+ K Sbjct: 86 QTVDFTDSRT--VDAINKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEK 143 Query: 284 QLTGLHEFWVDNSTSVSVPMLSGTGN-FQHWSDAQN--NFSVTRVPLGESVTLLLIQPQC 340 + T + F+V + V V M+S G F H S ++ NFS+ +P ++++I P Sbjct: 144 EFTSDYPFYVSPTEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDN 203 Query: 341 ASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEA 400 L+ +E + +F W + I + +P+ ++ GSYNL D L + L+ + G+ Sbjct: 204 IDGLESIEQNLTDTNFKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTG 263 Query: 401 NLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQ 437 + M +++ V +++ +++ E ++ Sbjct: 264 DYSNMSNSDVSVDAMIHKTYIDVNEEYTEAAAATSAL 300 >3OZQ-A nrPDB Length = 376 Score = 210 bits (535), Expect = 1e-54, Method: Composition-based stats. Identities = 54/387 (13%), Positives = 131/387 (33%), Gaps = 42/387 (10%) Query: 100 IANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEG 159 N +YK + + ++SP + L G TA +++ +L Sbjct: 14 AVNSFTPSVYKEVLKTEKA--NFLVSPFSAATLLALAQSGCRGDTAEEIRQVLHF----- 66 Query: 160 DCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGP 219 + + +G + + T ++ +++ F + + Sbjct: 67 -----------VGDREKAEGAVKEVLSKLTNEEYTLHTANKIYVKTNFSVREEF-QKIAV 114 Query: 220 FTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTYVHFQG 277 ++D S + AA+ +N +V+ T K+ ++ ++ + + ++F Sbjct: 115 EVYGAQSENVDFS-EKNDAAKLMNAWVEEQTQHKIQNLVDPEILNNLTRVVLINALYFNA 173 Query: 278 KM--RGFSQLTGLHEFWVDNSTSVSVPMLS-GTGNFQHWSDAQNNFSVTRVPLGESVTLL 334 K T +F V V + F ++ + + +P +L Sbjct: 174 KWLVPFPPFHTRKSDFHKSAKEVVQVDTMYLDEQYFNYYECHHLDAKLLELPFKGGASLT 233 Query: 335 LIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLST 394 ++ L +E + + N + + + LP+ +I + + + +L + + Sbjct: 234 IVLSNQIEGLVSLESKIKRSFLP---HNLTKQLVNVALPKFKIESTVDFKKVLKKLGVKK 290 Query: 395 LLGAEANLGKMG--DTNPRVGEVLNSILLELQAGEEEQPTES--------AQQPGSPEVL 444 G EA+L + + + ++ +++ E + P SP+ Sbjct: 291 AFGDEADLSGIAGEKGDLVISNIVQKSFIDVSEEGVEAAAATYIPVILPEMALPDSPK-- 348 Query: 445 DVTLSSPFLFAIYERDSGALHFLGRVD 471 + PF+F I + G + F GRV Sbjct: 349 QFIVDHPFIFYI--KVKGMILFAGRVT 373 >3STO-A nrPDB Length = 406 Score = 202 bits (514), Expect = 3e-52, Method: Composition-based stats. Identities = 63/391 (16%), Positives = 140/391 (35%), Gaps = 17/391 (4%) Query: 98 AMIANFMGFR-MYKMLSEARGVASGAVLSPPALFGTLVSF--YLGSLDPTASQLQVLLGV 154 A I++ F Y A + P + TL G+ T Q+ + + Sbjct: 14 ANISSHKAFTHAYLSTVTADFGGDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRL 73 Query: 155 PVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGS-SSQTPLLQSTVVGLFTAPGLRLKQPF 213 S ++ + Q + L ++ + + + G+F +++ F Sbjct: 74 KSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLNEKEENVVRISTGIFVEKTYEVERRF 133 Query: 214 VESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL-EGVSTDSTLFFNTY 272 ES+ + +D S + A IN +V + + + + D+ + Sbjct: 134 NESIAN-DSEGELKQVDFS-NRTSATVDINDWVDQQSNGLLEKFFTDDIPDDTAMILVNV 191 Query: 273 VHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGES 330 +F+ T +F++ ++V M++ G ++ F + PL + Sbjct: 192 FYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNT 251 Query: 331 -VTLLLIQPQCASDLDRVEVLVF-QHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLA 388 T +++ P L+ L+ ++KN + L LP+ ++ + +L L Sbjct: 252 RFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLK 311 Query: 389 QAKLSTLLGA-EANLGKMG-DTNPRVGEVLNSILLELQAGEEEQPTESAQQP----GSPE 442 + L +++L + + N V E + + +L+L E T ++ Sbjct: 312 SIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGIEATTVTSPIFVPFSAIIP 371 Query: 443 VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 473 +D ++ PF+ IY++ +V NP Sbjct: 372 EVDFHVTHPFICFIYDQQLTMPIMAAKVMNP 402 >3PZF-A nrPDB Length = 397 Score = 202 bits (513), Expect = 4e-52, Method: Composition-based stats. Identities = 59/382 (15%), Positives = 129/382 (33%), Gaps = 25/382 (6%) Query: 106 FRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRL 165 F + + + S VLSP ++ L Y AS V + + +S + Sbjct: 25 FDLMFVKEIFKNHNSNVVLSPFSVKILLTLIY------EASDTSFGNAVSNTKRELSSVI 78 Query: 166 DGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIF 225 + + LL + + L + F + + + + A+ Sbjct: 79 QNDNIDHTRSYYKQLLESAQQDNKDYDL--NIATNFFVDDFIEVINKYQQIANTHYHAML 136 Query: 226 PRSLDLSTDPVLAAQKINRFVQAVTGWKMNLP--LEGVSTDSTLFFNTYVHFQGKMR-GF 282 + S +P A IN +V T ++ + + + + ++F+G F Sbjct: 137 -EKVSYS-NPTQTAATINNWVSEHTNGRLREIVTPDSLEG-AVITLVNVIYFKGLWTYPF 193 Query: 283 SQLTGL-HEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGES-VTLLLIQPQC 340 ++ F+ + + G F + + A + R+P + + + I P Sbjct: 194 PEVANNVKPFYGTRGKPTNAQYMEQNGQFYYDNSADLGAQILRLPYRGNKLAMYFILPNP 253 Query: 341 ASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEA 400 + +++V + + + +TLP+ + S L + L Q + + A Sbjct: 254 DNTVNQVLDRINSASLHQALWYMEENEVNVTLPKFKFDFSEQLNEPLQQVGIREIFSQNA 313 Query: 401 NLGKM-----GDTNPRVGEVLNSILLELQAGEEEQPTES----AQQPGSPEVLDVTLSSP 451 +L + RV + + + E + + G V + P Sbjct: 314 SLPLLARGRGARDEVRVSRIFQKAGITINELGSEAYAATEIQLVNKFGGDGVQIFNANRP 373 Query: 452 FLFAIYERDSGALHFLGRVDNP 473 F+F I + G + F G+++NP Sbjct: 374 FIFFIEDETLGTMLFAGKIENP 395 >2PEF-A nrPDB Length = 373 Score = 197 bits (500), Expect = 1e-50, Method: Composition-based stats. Identities = 63/386 (16%), Positives = 142/386 (36%), Gaps = 41/386 (10%) Query: 101 ANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGD 160 ++K + +++SP + L G+ + T +Q++ LG + D Sbjct: 13 TADFSIELFK---NSIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALGKDISIED 69 Query: 161 CTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPF 220 L + + + ++ L + + F + F++ + + Sbjct: 70 -------------LNKYLYTYMKKLPNEEKSKLTIANSIW-FKENDFMPSKDFLQIIADY 115 Query: 221 TPA-IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM 279 A IF + D ST IN +V++ T ++ L + + ++ V F + Sbjct: 116 YKADIFKAAFDSSTVSD-----INNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDAEW 170 Query: 280 RGFSQLTGLHE--FWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGES-VTLLLI 336 + +HE F V ++ N + + +N + P ++ + + I Sbjct: 171 ETVYEKASVHEDIFTDVYGNRQKVEFMNSEENL--YIEEENAVGFVK-PYAKNHYSFVAI 227 Query: 337 QPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLL 396 P ++ + F+ IKN +R +LP+ + + + + L ++ Sbjct: 228 LPDENISVNEYIKTLTGQKFIDLIKNAKITLVRASLPKFKYEYTIKMNETLESLGMTDAF 287 Query: 397 GA-EANLGKMGDT---NPRVGEVLNSILLELQAGEEEQPT------ESAQQPGSPEVLDV 446 +A+ K+G + N + EVL+ + + + +A P + + V Sbjct: 288 LPDKADFSKLGKSDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNFK--TV 345 Query: 447 TLSSPFLFAIYERDSGALHFLGRVDN 472 L+ PF+FAI + + F+G V + Sbjct: 346 KLNRPFIFAIIDNSTNLPIFIGTVLS 371 >1M93-B nrPDB Length = 245 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 53/248 (21%), Positives = 110/248 (44%), Gaps = 13/248 (5%) Query: 196 STVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMN 255 ++ ++ K F+ +G +D + + A IN+ V T K+N Sbjct: 5 KSMNKVYGRYSAVFKDSFLRKIGDNFQT-----VDFTDSRTVDA--INKSVDIFTEGKIN 57 Query: 256 LPLEG-VSTDSTLFFNTYVHFQGKM--RGFSQLTGLHEFWVDNSTSVSVPMLSGTGN-FQ 311 L+ +S D++L + V+F+ K + T + F+V + V V M+S G F Sbjct: 58 PLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVSMMSMYGEAFN 117 Query: 312 HWSDAQN--NFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIR 369 H S ++ NFS+ +P ++++I P L+ +E + +F W + I Sbjct: 118 HASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTNFKKWSDSMDAMFID 177 Query: 370 LTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEE 429 + +P+ ++ GSYNL D L + L+ + G+ + M +++ V +++ +++ E Sbjct: 178 VHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNSDVSVDAMIHKTYIDVNEEYTE 237 Query: 430 QPTESAQQ 437 ++ Sbjct: 238 AAAATSAL 245 >6BJ5-B nrPDB Length = 315 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 50/330 (15%), Positives = 102/330 (30%), Gaps = 49/330 (14%) Query: 116 RGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQ 175 + V SP L L + + T ++ D L Sbjct: 27 YNESDNVVFSPYGLTSALSVLRIAAGGNTKREID-------VPESVVEDSDAFLALRE-- 77 Query: 176 AVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDP 235 LF + L+ F R + + Sbjct: 78 -------------------------LFVDASVPLRPEFTAEFSSRFNTSVQR-VTF--NS 109 Query: 236 VLAAQKINRFVQAVTGWKMNLPLE-GVSTDSTLFFNTYVHFQGKMR--GFSQLTGLHEFW 292 IN +V+ TG + L+ + D+ + + V + R T F+ Sbjct: 110 ENVKDVINSYVKDKTGGDVPRVLDASLDRDTKMLLLSSVRMKTSWRHVFDPSFTTDQPFY 169 Query: 293 VDNSTSVSVPMLSGTGNFQH--WSDAQNNFSVTRVPLGESVT-LLLIQPQCASDLDRVEV 349 + + V M++ + ++ +SVT +P T +LL+ P DL + Sbjct: 170 -SGNVTYKVRMMNKIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPD---DLGEIVR 225 Query: 350 LVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLG-AEANLGKMG-D 407 + WI+N ++ +P+ + +L+D L + + + A+ G+ Sbjct: 226 ALDLSLVRFWIRNMRKDVCQVVMPKFSVESVLDLRDALQRLGVRDAFDPSRADFGQASPS 285 Query: 408 TNPRVGEVLNSILLELQAGEEEQPTESAQQ 437 + V +VL + +E +++A Sbjct: 286 NDLYVTKVLQTSKIEADERGTTASSDTAIT 315 >1SNG-A nrPDB Length = 370 Score = 147 bits (371), Expect = 1e-35, Method: Composition-based stats. Identities = 62/382 (16%), Positives = 129/382 (33%), Gaps = 43/382 (11%) Query: 104 MGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTS 163 +++ L+EA + SP ++ L G+ T ++L LLG Sbjct: 17 FALHLHRRLAEAV-PDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAP----- 70 Query: 164 RLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPA 223 LL + + +P L S V L+ + + ++ F ++ + Sbjct: 71 ----------------LLAALDRAVTDSPDLASRTV-LWVSADVPVRSSFRATMHDRPDS 113 Query: 224 IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFNTYVHFQGKMRG 281 R+ D T+P +N + T + L V+ D + + + Sbjct: 114 DV-RTADFRTNPEGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTT 172 Query: 282 FSQ--LTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQ 339 + LT F VP + T + + + + + + + + ++ P Sbjct: 173 PFEAHLTRAGTFRTPRG-PKRVPFMHRTKTMPYATARG--WRMVTLHAHDELAVDVLLP- 228 Query: 340 CASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAE 399 ++ V + ++ L LP+ E+ + L ++LA+A + TL A Sbjct: 229 PGTNAAAVP---TAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTAS 285 Query: 400 ANLGKMGDTNPRVGEVLNSILLELQA------GEEEQPTESAQQPGSPEVLDVTLSSPFL 453 A+L + V V++ L + A + ++ PF Sbjct: 286 ADLSGISTVPLYVDTVIHQARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFH 345 Query: 454 FAIYERDSGALHFLGRVDNPQN 475 + GA+ FLG + +P + Sbjct: 346 IVVR--RRGAILFLGSIADPHD 365 >1MTP-A nrPDB Length = 323 Score = 126 bits (316), Expect = 2e-29, Method: Composition-based stats. Identities = 53/326 (16%), Positives = 112/326 (34%), Gaps = 35/326 (10%) Query: 104 MGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTS 163 +++ L+EA + SP ++ L G+ T ++L LLG Sbjct: 13 FALHLHRRLAEAV-PDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAP----- 66 Query: 164 RLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPA 223 LL + + +P L S V L+ + + ++ F ++ + Sbjct: 67 ----------------LLAALDRAVTDSPDLASRTV-LWVSADVPVRSSFRATMHDRPDS 109 Query: 224 IFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPL--EGVSTDSTLFFNTYVHFQGKMRG 281 R+ D T+P +N + T + L V+ D + + + Sbjct: 110 DV-RTADFRTNPEGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTT 168 Query: 282 FSQ--LTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQ 339 + LT F VP + T + + + + + + + + ++ P Sbjct: 169 PFEAHLTREGTFRTPRG-PKRVPFMHRTKTMPYATARG--WRMVTLHAHDELAVDVLLP- 224 Query: 340 CASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAE 399 ++ V + ++ L LP+ E+ + L ++LA+A + TL A Sbjct: 225 PGTNAAAVP---TAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTAS 281 Query: 400 ANLGKMGDTNPRVGEVLNSILLELQA 425 A+L + V V++ L + Sbjct: 282 ADLSGISTVPLYVDTVIHQARLRVDE 307 >5C98-A nrPDB Length = 382 Score = 118 bits (295), Expect = 7e-27, Method: Composition-based stats. Identities = 60/397 (15%), Positives = 115/397 (28%), Gaps = 51/397 (12%) Query: 97 VAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPV 156 + N +K +SP + L FY + QV G+P Sbjct: 17 IVAANNKFTLEYFKA---CYDEKCNCAVSPYHVRLALSMFYPLAGAAVQEDFQVAFGLP- 72 Query: 157 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 216 V A++ Q L + + LRL F Sbjct: 73 -----------EDVHAAIEQQQRLAQQLHDGQH-----LKALSFVLVEETLRLDSEFERL 116 Query: 217 LGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG-----VSTDSTLFFNT 271 +DL+ D A +N F Q ++ + + L Sbjct: 117 FHRTFQTTV-EPVDLTDDIPSALA-VNSFYQRA-NTEIEDFIGEGDVFSLPPCHKLML-- 171 Query: 272 YVHFQGKM-------RGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 324 F G R T L F N+ + V + T + + V Sbjct: 172 ---FSGVSVLTPLAIRFNPADTALELFQFINAPTQRVSTMHTTAFVRRCLHNELRCKVVD 228 Query: 325 VPL--GESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYN 382 +P +++L++ P ++L ++ + + L LP+ +R + Sbjct: 229 MPFDAASGLSMLVLLPYDGTELRQIVNSITPAHLAQIDERLQSCWTDLKLPKFFVREKTD 288 Query: 383 LQDLLAQAKLSTLLGAEANLGKMGDT-NPRVGEVLNSILLELQAGEEEQPTESAQQPGSP 441 + L + + + +L D+ R+ + L + E + P +P Sbjct: 289 PKQTLGKLGYGGVFEID-DLHVFHDSGRTRLNGFIQHCYLAVS----ESGSGIPAPPDTP 343 Query: 442 EVLDVTLSSPFLFAIYERDSGALHFLG---RVDNPQN 475 + + PF+F I G + +G + +P Sbjct: 344 SEFEFHANRPFMFLIRRTMDGNVLQVGNFSKYIDPDE 380 >4R9I-A nrPDB Length = 378 Score = 78.6 bits (192), Expect = 6e-15, Method: Composition-based stats. Identities = 57/372 (15%), Positives = 123/372 (33%), Gaps = 43/372 (11%) Query: 116 RGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQ 175 + L L L S + T ++L L + ++ +V+ Q Sbjct: 35 YEPERNQFSTAFPLLFMLSELSLNSKEDTTAELYKNLNLRSED----------EVVNVNQ 84 Query: 176 AVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDP 235 AV L T+ + ++ +T + F+++ +++D S D Sbjct: 85 AVNTNLNTKNEV-----YQSTLILNAYTDIDSPFSETFIQNFAKVFNGTV-KNIDYSND- 137 Query: 236 VLAAQKINRFVQAVTGWKMNLPLEG--VSTDSTLFFNTY--VHFQGKMRGFSQLTGLH-- 289 A I +Q+ +G + + L+ ++ D+ + Y ++F S + Sbjct: 138 --AVATIRDSLQSDSGNDIEIALKDGDINKDTGIILTAYTNIYF--PWGEASDSYRPYKQ 193 Query: 290 ---EFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLL--IQPQCASDL 344 F + T + G ++ V + L +T++L Sbjct: 194 IDISFTALDGTQSNKQAWYSEGAGKYAEIENLGIKVFQFSLKPGLTVVLGTSLNDNNDLS 253 Query: 345 DRVEVLVFQHDFLTWIKNPPPRAIRLTLP-QLEIRGSYNLQDLLAQAKL-STLLGAEAN- 401 L + + ++L +P +L +R S + + +A L + L + Sbjct: 254 GAFNKLRDPATLAYILTQTESKYLKLAVPIELTMRDSRDYIPEVKRAGLLTELFEKNFDG 313 Query: 402 LGKMGDTNP-RVGEVLNSILLELQAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERD 460 + D + +L+ LE + EEQ +P D P+ F + ++ Sbjct: 314 FDTVYDNKSGYISYMLSHTRLEFEQPTEEQAASVVAEP------DFIFDKPYFFLVLDQF 367 Query: 461 SGALHFLGRVDN 472 F+G + N Sbjct: 368 -NTPAFIGLITN 378 >2P6F-A nrPDB Length = 455 Score = 36.2 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 49/170 (28%), Gaps = 20/170 (11%) Query: 134 VSFYLGSLDPTASQLQVLLGVP-VKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTP 192 L + T L + E D T DGH + + L + ++ Sbjct: 206 AGIVLPAPVSTCRYTHRPLNWKKLYEVDFTGLPDGHTEEDMIA--ENALPAKTKTAGLRK 263 Query: 193 LLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGW 252 L + + +F + Q E + FT F + L Q I +V Sbjct: 264 LKKEDIDQVF--ELFKRYQSRFELIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPDG 321 Query: 253 KMNLPLEGVS-TDSTL-------FFNTYVH-------FQGKMRGFSQLTG 287 K+ S + L Y++ FQ K R + T Sbjct: 322 KITDFFSFYSLPFTILNNTKYKDLGIGYLYYYATDADFQFKDRFDPKATK 371 >5LN3-Z nrPDB Length = 908 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 61 VPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVAS 120 P+Q + SP D+ E+ +A D+ + +++ + + +ML E G Sbjct: 9 APVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDEL-EMLVERLGEKD 67 Query: 121 GAVLSP 126 ++ P Sbjct: 68 TSLYRP 73 >4XGV-A nrPDB Length = 340 Score = 32.0 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 50/159 (31%), Gaps = 14/159 (8%) Query: 60 PVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMI------ANFMGFRMYKMLS 113 P P + + V + + D +R+A++ A+ YK S Sbjct: 5 PQPAKTHATEVTVLEGKTMGTFWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDS 64 Query: 114 EARGVASGAVLSPPALFGTLV-----SFYLGSLDPTASQLQVLLGVPV---KEGDCTSRL 165 LSP + + S +G+ A + V V + ++ Sbjct: 65 ALMRFNDSQSLSPWPVSEAMADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQI 124 Query: 166 DGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 204 + + A++A GL + S LQ + L+ Sbjct: 125 PSQEQIDAMKAKTGLQHLTVINQSHQQYLQKDLPDLYVD 163 >4NOV-A nrPDB Length = 345 Score = 31.6 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 273 VHFQGKMRGFSQLTGLHEFW-----VDNSTSVSVPMLSGTGNFQHWSDAQNN 319 ++FQG +T F D T+ PM+ G + + + ++ Sbjct: 25 LYFQGSGAMTETMTEEKTFHKNPIIKDIYTADPAPMVYGDTLYLYTTHDEDE 76 >4GAX-A nrPDB Length = 563 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 42/137 (30%), Gaps = 10/137 (7%) Query: 317 QNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVL-VFQHDFLTW----IKNPPPRAIRLT 371 + +S R+ L + + L+ + E L +F W + P + Sbjct: 295 EPQYSRARIFLAKVIALVTLIDDIYDAYGTYEELKIFTEAIERWSITCLDMIPEYMKPIY 354 Query: 372 LPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQP 431 +L + ++++LA+ + + K N V E E+ Sbjct: 355 --KLFMDTYTEMEEILAKEGKTNIFNCGKEFVKDFVRNLMVEA---QWANEGHIPTTEEL 409 Query: 432 TESAQQPGSPEVLDVTL 448 A G +L T Sbjct: 410 DSVAVITGGANLLTTTC 426 >4GWP-B nrPDB Length = 687 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 23/56 (41%) Query: 35 LYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAED 90 L + T A NP+ + EPVP A + + D+L T+K ++ Sbjct: 21 LDPNLITLALSSNPNSSLHSPTSDEPVPESAGKADTSIRLEGDELENKTKKDNDKN 76 >6GCS-K nrPDB Length = 210 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 26 RVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAK-TSPVD 71 R + P ++ +++ A P V + PT P+P Q K S VD Sbjct: 12 RPTLVPATVIPQTRAYSAPAGTPRVSSSSMPTDFPLPSQQKPNSAVD 58 >3PPS-A nrPDB Length = 604 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 26/72 (36%), Gaps = 6/72 (8%) Query: 345 DRVEVLVFQHDFLTWIKNPPPRAIRLTLPQ-LEIRGSYNLQ-----DLLAQAKLSTLLGA 398 D + + + W+ P ++LP + + G L D L A + + Sbjct: 443 DNIVQVDAVDQWTYWLIENDPTNPIVSLPHPMHLHGHDFLVLGRSPDELPSAGVRHIFDP 502 Query: 399 EANLGKMGDTNP 410 +L ++ NP Sbjct: 503 AKDLPRLKGNNP 514 >3EC7-A nrPDB Length = 357 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 7/38 (18%), Positives = 18/38 (47%) Query: 337 QPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQ 374 P+ + E L+ + D + W+ N + +++ P+ Sbjct: 182 VPEYKTPQAIYETLIHEIDVMHWLLNEDYKTVKVYFPR 219 >3AJB-A nrPDB Length = 330 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 22/76 (28%), Gaps = 6/76 (7%) Query: 336 IQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTL 395 + P + L + D T R + L P L L + S L Sbjct: 195 MMPDEETPLAVQACGLSPRDITTIKLLNETRDM-LESPDFSTV----LNTCLNR-GFSRL 248 Query: 396 LGAEANLGKMGDTNPR 411 L A + + + + Sbjct: 249 LDNMAEFFRPTEQDLQ 264 >2CYC-A nrPDB Length = 375 Score = 28.5 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 15/102 (14%), Positives = 28/102 (27%), Gaps = 10/102 (9%) Query: 303 MLSGTGN-FQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVE--VLVFQHDFLTW 359 M G V + Q + + +E + H + Sbjct: 153 MGRQMGEAIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLRYHPIVHE 212 Query: 360 IKNPPPRAIRLTL-------PQLEIRGSYNLQDLLAQAKLST 394 + P A+ L P+ I +++ AQ K+S Sbjct: 213 GEKLKPVAVHHHLLLGLQEPPKWPIESEEEFKEIKAQMKMSK 254 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.132 0.353 Lambda K H 0.267 0.0408 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,873,306 Number of Sequences: 36641 Number of extensions: 619944 Number of successful extensions: 2300 Number of sequences better than 10.0: 73 Number of HSP's better than 10.0 without gapping: 94 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 1797 Number of HSP's gapped (non-prelim): 132 length of query: 477 length of database: 10,336,785 effective HSP length: 101 effective length of query: 376 effective length of database: 6,636,044 effective search space: 2495152544 effective search space used: 2495152544 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.1 bits)