BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00942 (248 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1I45-A nrPDB 500 e-142 6NEE-A nrPDB 306 6e-84 3TH6-A nrPDB 276 7e-75 4POC-A nrPDB 274 3e-74 4MKN-A nrPDB 270 5e-73 6CG9-A nrPDB 270 6e-73 2I9E-A nrPDB 269 8e-73 4OBT-A nrPDB 266 4e-72 1SW7-A nrPDB 264 2e-71 4OHQ-A nrPDB 264 2e-71 1MO0-A nrPDB 258 1e-69 5ZGA-A nrPDB 254 3e-68 5EYW-A nrPDB 247 3e-66 3PF3-A nrPDB 244 2e-65 2VXN-A nrPDB 237 3e-63 1CI1-A nrPDB 233 6e-62 3Q37-A nrPDB 233 8e-62 5CG7-A nrPDB 232 1e-61 1KV5-A nrPDB 228 2e-60 3KRS-A nrPDB 227 5e-60 5UPR-A nrPDB 225 2e-59 1TMH-A nrPDB 221 2e-58 1LZO-A nrPDB 218 1e-57 2V5B-A nrPDB 215 2e-56 2Y70-A nrPDB 214 3e-56 1TRI-A nrPDB 213 5e-56 5VWN-A nrPDB 204 3e-53 1B9B-A nrPDB 201 3e-52 1M6J-A nrPDB 194 3e-50 4NVT-A nrPDB 194 4e-50 3UWW-A nrPDB 187 3e-48 3KXQ-A nrPDB 187 4e-48 1AW2-A nrPDB 184 4e-47 5IBX-C nrPDB 179 7e-46 1YYA-A nrPDB 179 1e-45 4Y8F-A nrPDB 177 3e-45 4Y96-A nrPDB 177 5e-45 5UJW-A nrPDB 171 2e-43 1BTM-A nrPDB 170 6e-43 4X22-A nrPDB 166 6e-42 4G1K-A nrPDB 163 7e-41 3TA6-A nrPDB 154 5e-38 6BVE-A nrPDB 150 6e-37 4Y9A-A nrPDB 147 4e-36 4Y90-A nrPDB 145 2e-35 2JGQ-A nrPDB 116 1e-26 3S6D-A nrPDB 101 3e-22 1W0M-A nrPDB 39 0.003 5CSS-A nrPDB 39 0.003 2H6R-A nrPDB 35 0.021 3SQW-A nrPDB 32 0.36 3I62-A nrPDB 31 0.43 2RFC-A nrPDB 30 0.93 3LGD-A nrPDB 30 1.3 5D6O-A nrPDB 29 1.5 5IUJ-C nrPDB 28 2.6 5VU2-M nrPDB 28 2.9 1FOB-A nrPDB 28 3.0 3N42-F nrPDB 28 3.6 2XFB-A nrPDB 28 3.7 2XFC-A nrPDB 28 3.9 4LDZ-A nrPDB 28 4.3 3TC8-A nrPDB 28 4.9 1HG3-A nrPDB 27 5.8 4A2F-A nrPDB 27 6.1 6CR0-A nrPDB 27 7.2 1XSZ-A nrPDB 27 7.6 5JNM-A nrPDB 27 7.7 4C7P-A nrPDB 27 7.9 2QBW-A nrPDB 27 8.5 3CH8-A nrPDB 27 9.5 >1I45-A nrPDB Length = 248 Score = 500 bits (1288), Expect = e-142, Method: Compositional matrix adjust. Identities = 246/248 (99%), Positives = 248/248 (100%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT Sbjct: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 VGAQNAYLKASGAFTGENSVDQIKDVGAK+VILGHSERRSYFHEDDKFIADKTKFALGQG Sbjct: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKYVILGHSERRSYFHEDDKFIADKTKFALGQG 120 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD+TNVVVAYEPVWAIGTGLAATPED Sbjct: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDFTNVVVAYEPVWAIGTGLAATPED 180 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF Sbjct: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 Query: 241 VDIINSRN 248 VDIINSRN Sbjct: 241 VDIINSRN 248 >6NEE-A nrPDB Length = 252 Score = 306 bits (784), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 146/250 (58%), Positives = 191/250 (76%), Gaps = 3/250 (1%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKP-QVT 60 +R FFVGGN+K+NG+ +SIK +VE LN+A + N EVV+ PPA YL ++ S +KKP ++ Sbjct: 3 SRKFFVGGNWKMNGTLESIKALVETLNSAQLDPNTEVVVAPPAIYLPFARSKLKKPKEIQ 62 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQN Y K +GAFTGE S + +KD+G WVILGHSERR+ F E D+ IA+K K+AL QG Sbjct: 63 VAAQNCYTKPNGAFTGEISAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALDQG 122 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQ-LNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPE 179 + VI CIGETLEE++AGKT++VV RQ L A+ +++KDW+NVV+AYEPVWAIGTG ATPE Sbjct: 123 LKVIACIGETLEEREAGKTMEVVARQILKAIADKIKDWSNVVIAYEPVWAIGTGKVATPE 182 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-P 238 AQ++HA++RK+L + + A RI+YGGS N +N + D+DGFLVGGASLK P Sbjct: 183 QAQEVHAALRKWLKENVSPEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLKAP 242 Query: 239 EFVDIINSRN 248 EFVDIIN+R Sbjct: 243 EFVDIINARQ 252 >3TH6-A nrPDB Length = 249 Score = 276 bits (705), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 135/245 (55%), Positives = 170/245 (69%), Gaps = 1/245 (0%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 AR F VGGN+K++GSK SI++I L AS+ NVEV++ PA YLDY SL+ P V + Sbjct: 3 ARRFCVGGNWKMHGSKNSIRDICNTLKGASLDPNVEVIVACPAPYLDYCRSLLP-PSVAL 61 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQN Y GAFTGE S IKD G +WVILGHSERR F EDD I +K K AL G+ Sbjct: 62 AAQNCYKVEQGAFTGEISPGMIKDCGGQWVILGHSERRHVFKEDDVLIGEKIKHALESGL 121 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 VI CIGE LE+++AG+T +V RQ+ + VKDW+ VV+AYEPVWAIGTG ATP+ A Sbjct: 122 NVIACIGELLEDREAGRTEEVCFRQIKHIASNVKDWSKVVIAYEPVWAIGTGKTATPDQA 181 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q++H+ +R +L++ + AS++RI YGGS N N K D+DGFLVGGASLKPEFV Sbjct: 182 QEVHSKVRNWLSTNVSADVASKVRIQYGGSVNAGNCKELGRKPDIDGFLVGGASLKPEFV 241 Query: 242 DIINS 246 IIN+ Sbjct: 242 QIINA 246 >4POC-A nrPDB Length = 254 Score = 274 bits (700), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 131/247 (53%), Positives = 168/247 (68%), Gaps = 1/247 (0%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 +R FFVGGN+K+NG KQS+ E++ LN A +P + EVV PP Y+D++ + P++ V Sbjct: 9 SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAV 67 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQN Y +GAFTGE S IKD GA WV+LGHSERR F E D+ I K AL +G+ Sbjct: 68 AAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGL 127 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 GVI CIGE L+E++AG T VV Q + + VKDW+ VV+AYEPVWAIGTG ATP+ A Sbjct: 128 GVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQA 187 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q++H +R +L S + D A RI+YGGS G+ + DVDGFLVGGASLKPEFV Sbjct: 188 QEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFV 247 Query: 242 DIINSRN 248 DIIN++ Sbjct: 248 DIINAKQ 254 >4MKN-A nrPDB Length = 270 Score = 270 bits (689), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 126/243 (51%), Positives = 175/243 (72%), Gaps = 1/243 (0%) Query: 5 FFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQ 64 FFVGGN+K NGS ++ ++V+ LN +IP V+VV+ PP Y+DY + + + + + AQ Sbjct: 21 FFVGGNWKCNGSVANVAKLVDELNAGTIPRGVDVVVAPPFIYIDYVMQHLDRDKYQLSAQ 80 Query: 65 NAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVI 124 NA++ +GAFTGE S +Q+ D G WVILGHSERRS F E ++ +A KT AL G+GVI Sbjct: 81 NAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAGLGVI 140 Query: 125 LCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDI 184 CIGETLE++ +G V++ Q++A+++EVKDWT VV+AYEPVWAIGTG+ A+PE AQ++ Sbjct: 141 ACIGETLEQRNSGSVFKVLDAQMDALVDEVKDWTKVVLAYEPVWAIGTGVVASPEQAQEV 200 Query: 185 HASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFVDI 243 HA +R++ A KLG A +LRI+YGGS + +N + D+DGFLVGGASLK FV I Sbjct: 201 HAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGAAFVTI 260 Query: 244 INS 246 N+ Sbjct: 261 CNA 263 >6CG9-A nrPDB Length = 256 Score = 270 bits (689), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 128/248 (51%), Positives = 174/248 (70%), Gaps = 3/248 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN--VEVVICPPATYLDYSVSLVKKPQ 58 M R FFVGGN+K NG+ +++IV+ LN +P + VEVV+ PP +L S +++ + Sbjct: 4 MGRKFFVGGNWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQ-E 62 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 V AQN ++K GAFTGE S + + ++G WVILGHSERR+ E ++F+ DK +AL Sbjct: 63 FHVAAQNCWVKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALS 122 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATP 178 QG+ VI C+GETLE+++AG T+DVV Q A+ E++KDW+NVVVAYEPVWAIGTG ATP Sbjct: 123 QGLKVIACVGETLEQREAGSTMDVVAAQTKAIAEKIKDWSNVVVAYEPVWAIGTGKVATP 182 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 AQ++HAS+R +L + + A RI+YGGS +N + DVDGFLVGGASLKP Sbjct: 183 AQAQEVHASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKP 242 Query: 239 EFVDIINS 246 EF+DIIN+ Sbjct: 243 EFIDIINA 250 >2I9E-A nrPDB Length = 259 Score = 269 bits (688), Expect = 8e-73, Method: Compositional matrix adjust. Identities = 134/248 (54%), Positives = 170/248 (68%), Gaps = 1/248 (0%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 MAR F VGGN+K+NG K+ I EI+ L + + ++ EVV+ PA YL+ + V + Sbjct: 1 MARKFVVGGNWKMNGDKKQINEIIGFLKSGPLNQDTEVVVGVPAIYLELVRTCVPA-SIG 59 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQN Y GAFTGE S IKDVGA WVILGHSERR F E D+ IA+K AL G Sbjct: 60 VAAQNCYKVPKGAFTGEISPAMIKDVGADWVILGHSERRQIFGESDELIAEKVCHALESG 119 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 + VI CIGETLEE++AGKT +VV RQ A+ +V DW+NVV+AYEPVWAIGTG ATP+ Sbjct: 120 LKVIACIGETLEEREAGKTEEVVFRQTKAIAAKVNDWSNVVIAYEPVWAIGTGKTATPQQ 179 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 AQD+H ++R+++ + K + +RI YGGS +N + D+DGFLVGGASLKPEF Sbjct: 180 AQDVHKALRQWICENIDAKVGNSIRIQYGGSVTAANCKELASQPDIDGFLVGGASLKPEF 239 Query: 241 VDIINSRN 248 VDIIN+R Sbjct: 240 VDIINARQ 247 >4OBT-A nrPDB Length = 257 Score = 266 bits (681), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 129/248 (52%), Positives = 171/248 (68%), Gaps = 3/248 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN--VEVVICPPATYLDYSVSLVKKPQ 58 MAR FFVGGN+K NG+ + +K+IV LN A +P VEVV+ PP +L S ++ Sbjct: 4 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-D 62 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 V AQN ++K GAFTGE S + + ++ WVILGHSERR+ +E +F+ DK +AL Sbjct: 63 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 122 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATP 178 QG+ VI C+GETLEE++AG T+DVV Q A+ + V +W+NVV+AYEPVWAIGTG A+P Sbjct: 123 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASP 182 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 AQ++H +RK+LA + A+ RI+YGGS NG N +ADVDGFLVGGASLKP Sbjct: 183 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 242 Query: 239 EFVDIINS 246 EF+DII + Sbjct: 243 EFIDIIKA 250 >1SW7-A nrPDB Length = 248 Score = 264 bits (675), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 130/246 (52%), Positives = 168/246 (68%), Gaps = 1/246 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FFVGGN+K+NG K+S+ E++ LN A + + EVV P+ YLD++ + ++ V Sbjct: 4 RKFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLD-AKIGVA 62 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN Y GAFTGE S IKD+GA WVILGHSERR F E D+ I K AL +G+G Sbjct: 63 AQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLG 122 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 VI CIGE L+E++AG T VV Q A+ + VKDW+ VV+AYEPVWAIGTG ++TP+ AQ Sbjct: 123 VIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGNSSTPQQAQ 182 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVD 242 ++H +R +L S + D A RI+YGGS G N + DVDGFLVGGASLKPEFVD Sbjct: 183 EVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEFVD 242 Query: 243 IINSRN 248 IIN+++ Sbjct: 243 IINAKH 248 >4OHQ-A nrPDB Length = 256 Score = 264 bits (675), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 127/243 (52%), Positives = 173/243 (71%), Gaps = 2/243 (0%) Query: 5 FFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQ 64 FFVGGN+K NG+K SI +++ LN+A++ +V+VV+ PP Y+D S + ++ + Q Sbjct: 7 FFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTD-RIDISGQ 65 Query: 65 NAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVI 124 N+++ GAFTGE SV+Q+KD+G KWVILGHSERR E D+FI K +AL +G+GVI Sbjct: 66 NSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVI 125 Query: 125 LCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDI 184 CIGE LEE++AGKT DV QL A + V W N+VVAYEPVWAIGTG A+P+ AQ++ Sbjct: 126 ACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAYEPVWAIGTGKVASPQQAQEV 185 Query: 185 HASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFVDI 243 H ++R +L + ++ AS+ RI+YGGS NG N+ + D+DGFLVGGASLK PEF I Sbjct: 186 HVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEFATI 245 Query: 244 INS 246 +NS Sbjct: 246 VNS 248 >1MO0-A nrPDB Length = 275 Score = 258 bits (660), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 133/248 (53%), Positives = 166/248 (66%), Gaps = 1/248 (0%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 + R FFVGGN+K+NG S+ IV LN ++ +V+VV+ PPA YL Y+ S +K V Sbjct: 21 LTRKFFVGGNWKMNGDYASVDGIVTFLNASADNSSVDVVVAPPAPYLAYAKSKLKA-GVL 79 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQN Y GAFTGE S IKD+G +WVILGHSERR F E D IA+KT AL G Sbjct: 80 VAAQNCYKVPKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHALEAG 139 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 + V+ CIGE LEE++AG T DV RQL A++++ W N+V+AYEPVWAIGTG A+ E Sbjct: 140 IKVVFCIGEKLEEREAGHTKDVNFRQLQAIVDKGVSWENIVIAYEPVWAIGTGKTASGEQ 199 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 AQ++H IR FL K+ A RI+YGGS NA K D+DGFLVGGASLKP+F Sbjct: 200 AQEVHEWIRAFLKEKVSPAVADATRIIYGGSVTADNAAELGKKPDIDGFLVGGASLKPDF 259 Query: 241 VDIINSRN 248 V IIN+R+ Sbjct: 260 VKIINARS 267 >5ZGA-A nrPDB Length = 269 Score = 254 bits (648), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 123/244 (50%), Positives = 164/244 (67%), Gaps = 1/244 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FFVGGN+K+NGSK+ +++E L A I N EV++ PPA YL SV + V Sbjct: 25 RKFFVGGNWKMNGSKKENDKLIEMLTHAKIDPNTEVLVAPPALYLP-SVREKLDKRFHVA 83 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN Y SGAFTGE S +KDVG WVILGHSERR E D+ + +KT A+ GV Sbjct: 84 AQNCYKVPSGAFTGEVSPAMLKDVGCDWVILGHSERRHILLETDQLVGEKTAHAISAGVN 143 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 VI CIGE LEE++AGKT +V RQ+ A+ + + W ++V+AYEPVWAIGTG AT + AQ Sbjct: 144 VIACIGEKLEEREAGKTEEVCFRQMEAIRKNLSMWNHIVIAYEPVWAIGTGKTATEQQAQ 203 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVD 242 ++H ++R+++ K+ A +RI+YGGS +N T + DVDGFLVGGASLKP+F++ Sbjct: 204 EVHLAVRRWMEEKVSPAVAKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASLKPDFIE 263 Query: 243 IINS 246 I N+ Sbjct: 264 ICNA 267 >5EYW-A nrPDB Length = 249 Score = 247 bits (631), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 120/245 (48%), Positives = 162/245 (66%), Gaps = 1/245 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FFVGGN+K+NG K +I I+ + T + N EVV+ P YL Y+ + + + Sbjct: 5 RKFFVGGNWKMNGDKAAIDGIISFMKTGPLSPNTEVVVGCPQCYLMYTREHMPA-NIGIA 63 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN Y A GAFTGE S +KD G +WVILGHSERR+ F E D+ I++K AL G+ Sbjct: 64 AQNCYKVAKGAFTGEISPAMVKDCGCEWVILGHSERRNVFGEPDQLISEKVGHALEAGLK 123 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 VI CIGE LE+++ +T +VV Q+ A+L + DW+ VV+AYEPVWAIGTG A+PE AQ Sbjct: 124 VIPCIGEKLEDREGNRTQEVVFAQMKALLPNISDWSRVVLAYEPVWAIGTGKTASPEQAQ 183 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVD 242 ++HA +R++L + + A RI+YGGS + N K D+DGFLVGGA+LKP+FV Sbjct: 184 EVHADLRQWLRDNVNAEVAESTRIIYGGSVSAGNCQELAKKGDIDGFLVGGAALKPDFVQ 243 Query: 243 IINSR 247 IIN+R Sbjct: 244 IINAR 248 >3PF3-A nrPDB Length = 257 Score = 244 bits (624), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 121/248 (48%), Positives = 170/248 (68%), Gaps = 4/248 (1%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 AR F+GGNFK NGS IK V + IP++V+VVI P A +L +++ Q+ + Sbjct: 3 ARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIPDSVDVVIAPSAVHLSTAIAANTSKQLRI 62 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQN YL+ +GA+TGE SV+ ++D+G K VI+GHSERR E D+ A K K AL +G+ Sbjct: 63 AAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEKGM 122 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD----WTNVVVAYEPVWAIGTGLAAT 177 VI C+GETL+E+KA +T++V QL A+ +E+ + W VV+AYEPVW+IGTG+ AT Sbjct: 123 TVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVVAT 182 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 PE A+++H +RK+ A K+ + A +RI+YGGSANGSN ++DGFLVGGASLK Sbjct: 183 PEQAEEVHVGLRKWFAEKVAAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGASLK 242 Query: 238 PEFVDIIN 245 PEF+ +I+ Sbjct: 243 PEFMTMID 250 >2VXN-A nrPDB Length = 251 Score = 237 bits (605), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 118/241 (48%), Positives = 166/241 (68%), Gaps = 3/241 (1%) Query: 8 GGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAY 67 N+K NG+ SI+++V+ N +I +V+ V+ P ++ + ++ P+ + AQNA Sbjct: 10 AANWKCNGTTASIEKLVQVFNEHTISHDVQCVVAPTFVHIPLVQAKLRNPKYVISAQNAI 69 Query: 68 LKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCI 127 K SGAFTGE S+ +KD+G WVILGHSERR+Y+ E D+ +A K A QG VI CI Sbjct: 70 AK-SGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACI 128 Query: 128 GETLEEKKAGKTLDVVERQLNAVLEEV-KD-WTNVVVAYEPVWAIGTGLAATPEDAQDIH 185 GETL++++A +T VV Q +A+ ++ KD W VV+AYEPVWAIGTG ATPE AQ++H Sbjct: 129 GETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKVATPEQAQEVH 188 Query: 186 ASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIIN 245 +RK+++ +G A++LRILYGGS N +NA T K D++GFLVGGASLKPEF DII+ Sbjct: 189 LLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPEFRDIID 248 Query: 246 S 246 + Sbjct: 249 A 249 >1CI1-A nrPDB Length = 251 Score = 233 bits (594), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 114/241 (47%), Positives = 162/241 (67%), Gaps = 3/241 (1%) Query: 8 GGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAY 67 N+K NGS+ + ++E LN A+ +V+ V+ P ++ + + + P+ + AQNA Sbjct: 10 AANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPKFQIAAQNAI 69 Query: 68 LKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCI 127 + SGAFTGE S+ +KD G WV+LGHSERR Y+ E ++ +A+K A G VI+C+ Sbjct: 70 TR-SGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGFHVIVCV 128 Query: 128 GETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAATPEDAQDIH 185 GET EE++AG+T VV QL AV +++ W+ VV+AYEPVWAIGTG ATP+ AQ++H Sbjct: 129 GETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQQAQEVH 188 Query: 186 ASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIIN 245 +R+++ SKLG A++LRILYGGS NA T D++GFLVGGASLKPEFV+II Sbjct: 189 ELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEFVEIIE 248 Query: 246 S 246 + Sbjct: 249 A 249 >3Q37-A nrPDB Length = 251 Score = 233 bits (593), Expect = 8e-62, Method: Compositional matrix adjust. Identities = 117/241 (48%), Positives = 167/241 (69%), Gaps = 3/241 (1%) Query: 8 GGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAY 67 N+K NGS+QS+ E+++ N+ SI +V+ V+ P ++ + + + P+ + AQNA Sbjct: 10 AANWKCNGSQQSLSELIDLFNSTSINHDVQCVVAPTFLHIPMTKARLTNPKFQIAAQNAI 69 Query: 68 LKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCI 127 + SGAFTGE S+ +KD G WV+LGHSERR+Y+ E ++ +ADK A+ G VI+C+ Sbjct: 70 TR-SGAFTGEVSLQILKDYGISWVVLGHSERRAYYGETNEIVADKVAAAVASGFHVIVCV 128 Query: 128 GETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAATPEDAQDIH 185 GET EE++AG+T VV QL AV +++ W+ VV+AYEPVWAIGTG ATP+ AQ++H Sbjct: 129 GETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQQAQEVH 188 Query: 186 ASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIIN 245 +R+++ SKLG A++LRILYGGS NA T D++GFLVGGASLKPEFV+II Sbjct: 189 ELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEFVEIIE 248 Query: 246 S 246 + Sbjct: 249 A 249 >5CG7-A nrPDB Length = 271 Score = 232 bits (592), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 117/243 (48%), Positives = 165/243 (67%), Gaps = 3/243 (1%) Query: 6 FVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQN 65 V N+K NG+ SI+++V+ LN I +V+ V+ P ++ + + P+ V A+N Sbjct: 28 IVAANWKCNGTTASIEKLVQVLNEHQIDHDVQCVVAPSFVHIPMVQAKLCNPKYAVSAEN 87 Query: 66 AYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVIL 125 A K SGAFTGE S+ +KD+G WVILGHSERR+Y+ E D +A K A QG VI Sbjct: 88 AIAK-SGAFTGEVSMPILKDLGVSWVILGHSERRTYYGETDGVVAQKVADAYNQGFMVIA 146 Query: 126 CIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPEDAQD 183 CIGETL++++A +T VV Q A+ ++ + W+ +V+AYEPVWAIGTG ATPE AQ+ Sbjct: 147 CIGETLQQREANQTAKVVLSQTAAIAAKLPKEAWSQIVLAYEPVWAIGTGKVATPEQAQE 206 Query: 184 IHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDI 243 +HA +R++++ K+G+ A++LRILYGGS NA T K D++GFLVGGASLKPEF DI Sbjct: 207 VHALLRQWVSEKIGNGVATKLRILYGGSVTAGNAKTLYMKPDINGFLVGGASLKPEFRDI 266 Query: 244 INS 246 I++ Sbjct: 267 IDA 269 >1KV5-A nrPDB Length = 250 Score = 228 bits (581), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 122/239 (51%), Positives = 167/239 (69%), Gaps = 3/239 (1%) Query: 10 NFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLK 69 N+K NGS+QS+ E+++ N+ SI +V+ V+ +L + + P+ + AQNA K Sbjct: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAK 70 Query: 70 ASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGE 129 SGAFTGE S+ +KD G W++LGHSERR+Y+ E ++ +ADK A+ G VI CIGE Sbjct: 71 -SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGE 129 Query: 130 TLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPEDAQDIHAS 187 TL+E+++G+T VV Q+ A+ +++K DW VV+AYEPVWAIGTG ATP+ AQ+ HA Sbjct: 130 TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHAL 189 Query: 188 IRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINS 246 I +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPEFVDII + Sbjct: 190 ISSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKA 248 >3KRS-A nrPDB Length = 271 Score = 227 bits (578), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 114/253 (45%), Positives = 163/253 (64%), Gaps = 12/253 (4%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKK---- 56 M+R +FVGGNFK NG+K+S+K +++ N EV + P + + +SLVK+ Sbjct: 22 MSRKYFVGGNFKCNGTKESLKTLIDSFKQVE-SSNSEVYVFPTSLH----ISLVKEFFGN 76 Query: 57 --PQV-TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKT 113 P V +G+QN +GAFTGE S + +KD+ ++GHSERR Y+ E D+ + +K Sbjct: 77 DHPGVFKIGSQNISCTGNGAFTGEVSCEMLKDMDVDCSLVGHSERRQYYSETDQIVNNKV 136 Query: 114 KFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTG 173 K L G+ ++LCIGE+L E++ GKT DV+++QL L++V D +N+V+AYEP+WAIGTG Sbjct: 137 KKGLENGLKIVLCIGESLSERETGKTNDVIQKQLTEALKDVSDLSNLVIAYEPIWAIGTG 196 Query: 174 LAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGG 233 + ATP AQ+ HA IR+++ + +S LRI+YGGS N AD+DGFLVGG Sbjct: 197 VVATPGQAQEAHAFIREYVTRMYNPQVSSNLRIIYGGSVTPDNCNELIKCADIDGFLVGG 256 Query: 234 ASLKPEFVDIINS 246 ASLKP F II S Sbjct: 257 ASLKPTFAKIIES 269 >5UPR-A nrPDB Length = 265 Score = 225 bits (573), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 120/254 (47%), Positives = 167/254 (65%), Gaps = 9/254 (3%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIP-ENVEVVICPPATYLDYSVSLVKKPQVT 60 AR FVGGN+K NG+ +E+V+ LN+A + E V+VV+ PP+ ++ +++P+V Sbjct: 7 ARRGFVGGNWKCNGTTAKTQELVDMLNSAPVSFEQVDVVVAPPSLFISQVQDSLRQPRVQ 66 Query: 61 VGAQNAYLK-ASGAFTGENSVDQIKDVGAKWVILGHSERRSYFH----EDDKFIADKTKF 115 V AQ++ + A GAFTGE S IK+ WV+LGHSERR+ F E ++ +A K + Sbjct: 67 VAAQDSSTQQAYGAFTGELSPKMIKEKNIPWVVLGHSERRAGFGGQPGESNQVVAKKVRA 126 Query: 116 ALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD---WTNVVVAYEPVWAIGT 172 AL +G+ VILCIGETLEE+++G+T V+ QL AV + V + W ++V+AYEPVWAIGT Sbjct: 127 ALNEGLSVILCIGETLEERESGQTQKVLSEQLEAVRQAVPEADAWKSIVIAYEPVWAIGT 186 Query: 173 GLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 G AT AQ+ H IR +LA + K A R++YGGS GSNA + DVDGFLVG Sbjct: 187 GKTATAALAQETHRDIRNWLAQAVSPKVAEATRVIYGGSVKGSNAKELFEGEDVDGFLVG 246 Query: 233 GASLKPEFVDIINS 246 GASL +FV II++ Sbjct: 247 GASLTGDFVSIIDA 260 >1TMH-A nrPDB Length = 254 Score = 221 bits (564), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 121/248 (48%), Positives = 156/248 (62%), Gaps = 6/248 (2%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNT--ASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 R V GN+KLNGS+ + E+V L A + V I PP Y+D + + + Sbjct: 2 RHPLVMGNWKLNGSRHMVHELVSNLRKELAGVA-GCAVAIAPPEMYIDMAKREAEGSHIM 60 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 +GAQN L SGAFTGE S +KD+GA+++I+GHSERR+Y E D+ IA K QG Sbjct: 61 LGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQG 120 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVL--EEVKDWTNVVVAYEPVWAIGTGLAATP 178 + +LCIGET E +AGKT +V RQ++AVL + + V+AYEPVWAIGTG +ATP Sbjct: 121 LTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATP 180 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 AQ +H IR +A K+ A ++ I YGGS N SNA + DVDGFLVGGASLKP Sbjct: 181 AQAQAVHKFIRDHIA-KVDANIAEQVIIQYGGSVNASNAAELFAQHDVDGFLVGGASLKP 239 Query: 239 EFVDIINS 246 EFVDIIN+ Sbjct: 240 EFVDIINA 247 >1LZO-A nrPDB Length = 248 Score = 218 bits (556), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 103/247 (41%), Positives = 161/247 (65%), Gaps = 2/247 (0%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASI-PENVEVVICPPATYLDYSVSLVKKPQV 59 MAR +FV N+K NG+ +SIK + N P ++VV+ P + + D++ L++ + Sbjct: 1 MARKYFVAANWKCNGTLESIKSLTNSFNNLDFDPSKLDVVVFPVSVHYDHTRKLLQ-SKF 59 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 + G QN +G++TGE S + KD+ ++VI+GH ERR YFHE D+ + +K + +L Sbjct: 60 STGIQNVSKFGNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLKN 119 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPE 179 + ++C GE+LE+++ KT++V+ +Q+ A ++ + ++ NV++ YEP+WAIGTG ATPE Sbjct: 120 NLKAVVCFGESLEQREQNKTIEVITKQVKAFVDLIDNFDNVILVYEPLWAIGTGKTATPE 179 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 AQ +H IRK + G+K A+++RILYGGS N N + + D+DGFLVG ASLK Sbjct: 180 QAQLVHKEIRKIVKDTCGEKQANQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASLKES 239 Query: 240 FVDIINS 246 FVDII S Sbjct: 240 FVDIIKS 246 >2V5B-A nrPDB Length = 244 Score = 215 bits (547), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 106/241 (43%), Positives = 155/241 (64%), Gaps = 10/241 (4%) Query: 8 GGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAY 67 N+K NGS+ + ++E LN A+ +V+ V+ P ++ + + + P+ + AQNA Sbjct: 10 AANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPKFQIAAQNA- 68 Query: 68 LKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCI 127 +++ +KD G WV+LGHSERR Y+ E ++ +A+K A G VI+C+ Sbjct: 69 -------GNADALASLKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGFHVIVCV 121 Query: 128 GETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAATPEDAQDIH 185 GET EE++AG+T VV QL AV +++ W+ VV+AYEPVWAIGTG ATP+ AQ++H Sbjct: 122 GETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQQAQEVH 181 Query: 186 ASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIIN 245 +R+++ SKLG A++LRILYGGS NA T D++GFLVGGASLKPEFV+II Sbjct: 182 ELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEFVEIIE 241 Query: 246 S 246 + Sbjct: 242 A 242 >2Y70-A nrPDB Length = 245 Score = 214 bits (545), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 114/242 (47%), Positives = 161/242 (66%), Gaps = 14/242 (5%) Query: 10 NFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLD---YSVSLVKKPQVTVGAQNA 66 N+K NGS+QS+ E+++ N+ SI +V+ V+ P + Y+ + + P+ + AQNA Sbjct: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVAP-SWYMGAQAMTKERLSHPKFVIAAQNA 69 Query: 67 YLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILC 126 +++ +KD G W++L HSERR+Y+ E ++ +ADK A+ G VI C Sbjct: 70 --------GNADALASLKDFGISWIVLDHSERRAYYGETNEIVADKVAAAVASGFMVIAC 121 Query: 127 IGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPEDAQDI 184 IGETL+E+ +G+T VV Q+ A+ +++K DW VV+AYEPVWAIGTG ATP+ AQ+ Sbjct: 122 IGETLQERSSGRTAVVVLTQITAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEA 181 Query: 185 HASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDII 244 HA IR +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPEFVDII Sbjct: 182 HALIRSWVSSKVGADVAGELRILYGGSVNGRNARTLYQQRDVNGFLVGGASLKPEFVDII 241 Query: 245 NS 246 + Sbjct: 242 KA 243 >1TRI-A nrPDB Length = 243 Score = 213 bits (543), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 114/239 (47%), Positives = 161/239 (67%), Gaps = 10/239 (4%) Query: 10 NFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLK 69 N+K NGS+QS+ E+++ N+ SI +V+ V+ +L + + P+ + AQNA Sbjct: 11 NWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNA--- 67 Query: 70 ASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGE 129 +++ +KD G W++LGHSERR+Y+ E ++ +ADK A+ G VI CIGE Sbjct: 68 -----GNADALASLKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACIGE 122 Query: 130 TLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPEDAQDIHAS 187 TL+E+++G+T VV Q+ A+ +++K DW VV+AYEPVWAIGTG ATP+ AQ+ HA Sbjct: 123 TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHAL 182 Query: 188 IRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINS 246 IR +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPEFVDII + Sbjct: 183 IRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKA 241 >5VWN-A nrPDB Length = 246 Score = 204 bits (519), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 112/247 (45%), Positives = 155/247 (62%), Gaps = 10/247 (4%) Query: 3 RTFFVGGNFKLNG-SKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 RTFFVGGN+K N + Q +++VE LN A + NVEVV+ P +L ++K V Sbjct: 2 RTFFVGGNWKANPKTVQEAEKLVEMLNGAKVEGNVEVVVAAPFVFLPTLQQKLRK-DWKV 60 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 A+N + K +G +V IK G +W ILGHSERR EDD+F+A K KFAL G+ Sbjct: 61 SAENVFTKPNG------TVPMIKSFGIEWTILGHSERRDILKEDDEFLAAKAKFALENGM 114 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPE 179 +I C GE L E++AGK + V Q+ ++ + W +VV+AYEP+WAIGTG A+ + Sbjct: 115 KIIYCCGEHLSEREAGKASEFVSAQIEKMIPAIPAGKWDDVVIAYEPIWAIGTGKVASTQ 174 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 DAQ++ IR LA+K+G A+++RILYGGS +N DVDGFLVGGASL+ Sbjct: 175 DAQEMCKVIRDILAAKVGADIANKVRILYGGSVKPNNCNELAACPDVDGFLVGGASLEAG 234 Query: 240 FVDIINS 246 F++I+NS Sbjct: 235 FINIVNS 241 >1B9B-A nrPDB Length = 255 Score = 201 bits (510), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 108/249 (43%), Positives = 153/249 (61%), Gaps = 9/249 (3%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERL-NTASIPENVEVVICPPATYLDYSVSLVKKPQV 59 + R + GN+K++ + K+ V L N + E+V+CPP T L ++ + Sbjct: 1 ITRKLILAGNWKMHKTISEAKKFVSLLVNELHDVKEFEIVVCPPFTALSEVGEILSGRNI 60 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 +GAQN + + GAFTGE S ++++G ++VI+GHSERR F EDD+FI K K L + Sbjct: 61 KLGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLEK 120 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVL-----EEVKDWTNVVVAYEPVWAIGTGL 174 G+ ILC+GETLEE++ G T VVE+Q+ EE K VV+AYEPVWAIGTG Sbjct: 121 GMTPILCVGETLEEREKGLTFCVVEKQVREGFYGLDKEEAK---RVVIAYEPVWAIGTGR 177 Query: 175 AATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGA 234 ATP+ AQ++HA IRK L+ ++ A +RILYGGS N + + D+DG LVGGA Sbjct: 178 VATPQQAQEVHAFIRKLLSEMYDEETAGSIRILYGGSIKPDNFLGLIVQKDIDGGLVGGA 237 Query: 235 SLKPEFVDI 243 SLK F+++ Sbjct: 238 SLKESFIEL 246 >1M6J-A nrPDB Length = 261 Score = 194 bits (493), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 110/255 (43%), Positives = 154/255 (60%), Gaps = 11/255 (4%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNT---ASIPENVEVVICPPATYLDYSVSLV---- 54 A F VGGN+K NG+ SI+ + + + A + + VEV++ P Y+ ++ Sbjct: 3 AGKFVVGGNWKCNGTLASIETLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQILAGEA 62 Query: 55 KKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTK 114 + V A+NA+ K SGA+TGE V + D +VILGHSERR FHE ++ +A+K K Sbjct: 63 NGANILVSAENAWTK-SGAYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVAEKVK 121 Query: 115 FALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGT 172 A+ G+ VI CIGET ++ A +T +VV QL A+ + W N+++AYEPVWAIGT Sbjct: 122 VAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVWAIGT 181 Query: 173 GLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 G ATP+ AQ++H IRK++ + + A RI YGGS N +N KAD+DGFLVG Sbjct: 182 GKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDGFLVG 241 Query: 233 GASL-KPEFVDIINS 246 GASL +F IINS Sbjct: 242 GASLDAAKFKTIINS 256 >4NVT-A nrPDB Length = 262 Score = 194 bits (492), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 109/247 (44%), Positives = 152/247 (61%), Gaps = 5/247 (2%) Query: 6 FVGGNFKLNGSKQSIKEI--VERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGA 63 V GN+K+NG +S+ E+ + ++ + ++ VIC PAT L + ++ V +G Sbjct: 16 LVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGLGG 75 Query: 64 QNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGV 123 Q+A+ K SGA TG+ S + +K+ GA VILGHSERR+ HE +K I KT+ A G+ Sbjct: 76 QDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGLVA 135 Query: 124 ILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQD 183 I+C+GET E+KA + LDV+ QL+ L + N ++AYEPVWAIGTGL T +D + Sbjct: 136 IVCVGETASERKAERALDVIGDQLSGSLPDGVTAENTIIAYEPVWAIGTGLTPTVQDVRA 195 Query: 184 IHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFVD 242 HA +R+ L + G K A LR+LYGGS SNA ADVDG LVGGASLK +F+ Sbjct: 196 AHAFMREQLIERFGAKGA-HLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAADFLA 254 Query: 243 IINS-RN 248 I + RN Sbjct: 255 ICETYRN 261 >3UWW-A nrPDB Length = 261 Score = 187 bits (475), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 104/248 (41%), Positives = 151/248 (60%), Gaps = 6/248 (2%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ---V 59 RT + GN+K+N + Q K+ V L T + VE VIC PA LD + VK+ + + Sbjct: 10 RTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGL 69 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 +GAQN Y + +GAFTGE S + D+G K+V++GHSERR FHE D+ I K Sbjct: 70 EIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKH 129 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAAT 177 G+ I+C+GET EE+++GK DVV Q+ + + + +VV+AYEP+WAIGTG ++T Sbjct: 130 GMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSST 189 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 EDA ++ A +R+ +A + + RI YGGS +N + + D+DG LVGGASLK Sbjct: 190 SEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLK 249 Query: 238 PE-FVDII 244 E FV ++ Sbjct: 250 VEDFVQLL 257 >3KXQ-A nrPDB Length = 275 Score = 187 bits (474), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 99/245 (40%), Positives = 149/245 (60%), Gaps = 8/245 (3%) Query: 6 FVGGNFKLNGSKQSIKEIVERLNTASIPENV----EVVICPPATYLDYSVSLVKKPQVTV 61 F+ GN+K+NG+ +S+ E+ R A I ++ E +IC PAT L + ++ + + Sbjct: 29 FIAGNWKMNGTGESLGEL--RAIAAGISSDLGRLFEALICVPATLLSRAFDILGGENILL 86 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 G QN + G +TG+ S +K+ GA VI+GHSERR+ + E D + K + A G+ Sbjct: 87 GGQNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWRAGL 146 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 ++C+GETLEE+K+ K LDV+ RQL L + N+++AYEPVWA+GTG AT D Sbjct: 147 VALICVGETLEERKSNKVLDVLTRQLEGSLPDGATAENIIIAYEPVWAVGTGNTATSADV 206 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP-EF 240 ++HA I + S+ GD+ A ++R+LYGGS SNA A V+G L+GGASLK +F Sbjct: 207 AEVHAFIHHKMHSRFGDEGA-KIRLLYGGSVKPSNAFELLSTAHVNGALIGGASLKAIDF 265 Query: 241 VDIIN 245 + I + Sbjct: 266 LTICD 270 >1AW2-A nrPDB Length = 256 Score = 184 bits (466), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 104/239 (43%), Positives = 147/239 (61%), Gaps = 6/239 (2%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTA-SIPENVEVVICPPATYLDYSVSLVKKP--QV 59 R V GN+KLNGSK+ + +++ LN V+V + PPA ++D + + + + Sbjct: 2 RHPVVMGNWKLNGSKEMVVDLLNGLNAELEGVTGVDVAVAPPALFVDLAERTLTEAGSAI 61 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 +GAQN L SGAFTG+ S +K+ GA +I+GHSERR Y E D+F+A K F Sbjct: 62 ILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHAESDEFVAKKFAFLKEN 121 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVL--EEVKDWTNVVVAYEPVWAIGTGLAAT 177 G+ +LCIGE+ + +AG+T+ V RQL+AV+ + V+ ++AYEP+WAIGTG AAT Sbjct: 122 GLTPVLCIGESDAQNEAGETMAVCARQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAAT 181 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 EDAQ IHA IR +A K + A + I YGGS NA + + D+DG LVGGA+L Sbjct: 182 AEDAQRIHAQIRAHIAEK-SEAVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAAL 239 >5IBX-C nrPDB Length = 255 Score = 179 bits (455), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 98/243 (40%), Positives = 145/243 (59%), Gaps = 5/243 (2%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN--VEVVICPPATYLDYSVSLVKKPQ 58 M+R F+ GN+K+N + + K VE + + +P + VE I PA L +++ K Sbjct: 4 MSRKPFIAGNWKMNKNPEEAKAFVEAV-ASKLPSSDLVEAGIAAPALDLTTVLAVAKGSN 62 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 + V AQN Y + +GAFTGE S +K++G +V++GHSERR YFHE D+ I K K Sbjct: 63 LKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFA 122 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLE--EVKDWTNVVVAYEPVWAIGTGLAA 176 G+ I+C GE+LE +AGK + V Q++A L + V+AYEP+WAIGTG +A Sbjct: 123 NGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSA 182 Query: 177 TPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 + +DAQ + +R +A+ G + A ++R+ YGGS N ++ DVDG LVGGASL Sbjct: 183 SQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASL 242 Query: 237 KPE 239 + E Sbjct: 243 EAE 245 >1YYA-A nrPDB Length = 250 Score = 179 bits (453), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 98/239 (41%), Positives = 135/239 (56%), Gaps = 2/239 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R V GN+K++ + + L P E + P L + ++ + QV G Sbjct: 2 RRVLVAGNWKMHKTPSEARVWFAELKRLLPPLQSEAAVLPAFPILPVAKEVLAETQVGYG 61 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQ+ GA+TGE S + D+G ++ I+GHSERR Y E D +A+K K L +G+ Sbjct: 62 AQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEGIT 121 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLE--EVKDWTNVVVAYEPVWAIGTGLAATPED 180 ILC+GE LE ++ G+ + RQL LE E +V+AYEPVWAIGTG ATPED Sbjct: 122 PILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATPED 181 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 A+ +H +IRK L+ + G+ AS +RILYGGS N N +VDG LVGGASL+ E Sbjct: 182 AEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLELE 240 >4Y8F-A nrPDB Length = 251 Score = 177 bits (449), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 99/246 (40%), Positives = 142/246 (57%), Gaps = 3/246 (1%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 RT + GN+K++ + ++VE L EVV+CP LD V+ + VG Sbjct: 5 RTPIIAGNWKMHYTIDEAVKLVEELKPLVKDAKCEVVVCPTFVCLDAVKKAVEGTNIKVG 64 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN + + GAFTGE + ++ + +VI+GHSERR YF+E D+ K K A + Sbjct: 65 AQNMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHNLT 124 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPED 180 ILC GETLE+++ G T DV++ Q+ A LE + + VV+AYEP+WAIGTG AT + Sbjct: 125 PILCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATSDQ 184 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL-KPE 239 A + A+IR +A G + A ++RI YGGS + K+D+DG LVGGASL + Sbjct: 185 ANETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASLVAAD 244 Query: 240 FVDIIN 245 F I+N Sbjct: 245 FAQIVN 250 >4Y96-A nrPDB Length = 255 Score = 177 bits (448), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 101/247 (40%), Positives = 140/247 (56%), Gaps = 3/247 (1%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FV GN+K+N + K + + + V V + PP +L ++K V +G Sbjct: 7 RKKFVAGNWKMNTTLAEAKALGAAVAKGVTDDRVTVAVFPPYPWLTAVGEVLKGSPVALG 66 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQ+ + GAFTGE S + + G K+ ++GHSERR E + FI K AL +G+ Sbjct: 67 AQDVSSEKKGAFTGEVSPAMLLETGCKYALIGHSERRHIIGESETFINHKVHTALEEGLS 126 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAATPED 180 V+LC+GETL E++ G V +RQ+ A + D + +V+AYEPVWAIGTG ATPE Sbjct: 127 VVLCMGETLAERERGLQERVFQRQVYAACAGLTDEQFGRIVIAYEPVWAIGTGKVATPEQ 186 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE- 239 AQ+ HA +R L GDK A I+YGGS N V + DVDG LVGGASLK + Sbjct: 187 AQEAHAFVRSKLRLLYGDKIADSTPIVYGGSVTPDNTVGLMSQPDVDGALVGGASLKADS 246 Query: 240 FVDIINS 246 F+ I+ + Sbjct: 247 FLAIVKA 253 >5UJW-A nrPDB Length = 253 Score = 171 bits (434), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 97/247 (39%), Positives = 148/247 (59%), Gaps = 6/247 (2%) Query: 6 FVGGNFKLNGSKQSIKEIVERLNTASI-PENVEVVICPPATYLDYSVSLVKKPQVTVGAQ 64 + GN+K+NG+ SIKE+ ++ V + + P + Y+ +S + + +V VG Q Sbjct: 4 LIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPE-KVGVGLQ 62 Query: 65 NAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVI 124 N GA+TGE S ++D+G ++++GHSERRS F E D+ + K + + + Sbjct: 63 NITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPV 122 Query: 125 LCIGETLEEKKAGKTLDVVERQLNAVLE--EVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 +CIGE+L+++++GK V+ QL+ +LE V+ VV+AYEPVWAIGTG+ A+ E Q Sbjct: 123 VCIGESLDDRQSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQIQ 182 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFV 241 + H IR LA K+ ++ A ++I+YGGS NA DVDG L+GGASLK EF Sbjct: 183 ETHQFIRSLLA-KVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEFN 241 Query: 242 DIINSRN 248 +IIN N Sbjct: 242 EIINQAN 248 >1BTM-A nrPDB Length = 252 Score = 170 bits (430), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 99/252 (39%), Positives = 143/252 (56%), Gaps = 12/252 (4%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEV--VICPPATYLDYSVSLVKKPQVT 60 R + GN+K++ + + VE + +P EV V+C P +LD V + Sbjct: 1 RKPIIAGNWKMHKTLAEAVQFVEDVK-GHVPPADEVISVVCAPFLFLDRLVQAADGTDLK 59 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 +GAQ + GA+TGE S +KD+G +VILGHSERR F E D+ + K A +G Sbjct: 60 IGAQTMHFADQGAYTGEVSPVMLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRG 119 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVL-----EEVKDWTNVVVAYEPVWAIGTGLA 175 + I+C GE+LEE++AG+T VV Q+ L E+VK V+AYEP+WAIGTG + Sbjct: 120 LIPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVK---QAVIAYEPIWAIGTGKS 176 Query: 176 ATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGAS 235 +TPEDA + IR ++ G +AA +RI YGGS N F + +DG LVGGAS Sbjct: 177 STPEDANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGPLVGGAS 236 Query: 236 LKP-EFVDIINS 246 L+P F+ ++ + Sbjct: 237 LEPASFLQLVEA 248 >4X22-A nrPDB Length = 250 Score = 166 bits (421), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 97/244 (39%), Positives = 142/244 (58%), Gaps = 12/244 (4%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVE-----RLNTASIPENVEVVICPPATYLDYSVSLVKKP 57 R + GN+K+N S+KE V R SI ++ ++ P +L+ +++ Sbjct: 2 RKTIIAGNWKMN---LSLKEAVFLAHSIREKIPSISKDKVSMVFPSTLHLENVSKILEGS 58 Query: 58 QVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFAL 117 V VGAQN Y AFTGE S DQ+K++G K V++GHSERR + E + F DK +F L Sbjct: 59 SVIVGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLL 118 Query: 118 GQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLA 175 V+ C+GETL E+++GKTL+V+ Q+ L+ + ++N+++AYEPVWAIGTG Sbjct: 119 KNEFTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKV 178 Query: 176 ATPEDAQDIHASIRKFLASKL--GDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGG 233 ATP AQ++H+ IRK ++ + + ILYGGS N + D+DG LVGG Sbjct: 179 ATPSQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGG 238 Query: 234 ASLK 237 AS K Sbjct: 239 ASQK 242 >4G1K-A nrPDB Length = 272 Score = 163 bits (412), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 95/243 (39%), Positives = 146/243 (60%), Gaps = 9/243 (3%) Query: 9 GNFKLNGSKQSIKEIVERL--NTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNA 66 GN+K++G + ++ + ++ +NV + +C P YL + + ++ +V+ G+Q+ Sbjct: 32 GNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQDV 91 Query: 67 YLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILC 126 GA+TGE + + + GA + I+GHSERR+Y E ++ +A K + AL G+ I+C Sbjct: 92 SAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPIVC 151 Query: 127 IGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPEDAQDI 184 +GETL E++AG T VV QL+AVL + + +VVAYEPVWAIGTG +AT E AQ + Sbjct: 152 VGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGKSATAEQAQQV 211 Query: 185 HASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP-EFVDI 243 HA FL +L K A + +LYGGS NA + D+DG L+GGASLK +F+ I Sbjct: 212 HA----FLRGRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKSGDFLAI 267 Query: 244 INS 246 + Sbjct: 268 CRA 270 >3TA6-A nrPDB Length = 267 Score = 154 bits (388), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 101/248 (40%), Positives = 146/248 (58%), Gaps = 9/248 (3%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPE----NVEVVICPPATYLDYSVSLVK- 55 M+R + GN+K+N + +V+++ S+P+ V+V + PP T L +LV Sbjct: 1 MSRKPLIAGNWKMNLNHYEAIALVQKI-AFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDG 59 Query: 56 -KPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTK 114 K ++T GAQ+ SGA+TG+ S + +G +V++GHSERR+Y +EDD +A K Sbjct: 60 DKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAA 119 Query: 115 FALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGT 172 AL G+ I+CIGE L+ ++AG + QL L + + +VV+AYEPVWAIGT Sbjct: 120 TALKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGT 179 Query: 173 GLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 G A+ DAQ++ A+IRK LAS + A +R+LYGGS N N + DVDG LVG Sbjct: 180 GRVASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVG 239 Query: 233 GASLKPEF 240 GASL E Sbjct: 240 GASLDGEH 247 >6BVE-A nrPDB Length = 245 Score = 150 bits (378), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 92/251 (36%), Positives = 141/251 (56%), Gaps = 21/251 (8%) Query: 3 RTFFVGGNFKLNGSK-------QSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVK 55 R + GN+K++ ++ Q K ++E E+ EVV+C P T L + Sbjct: 5 RKIIIAGNWKMHKTQAEAQAFLQGFKPLIE-----DAAESREVVLCVPFTDLSGMSQQLH 59 Query: 56 KPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKF 115 +V +GAQN + +ASGA+TGE S + ++G +V++GHSERR YF E D+ + Sbjct: 60 GGRVRLGAQNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLA 119 Query: 116 ALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLA 175 A G+ ILC+GE+ ++ AG+T V+ Q+ L V D +N+V+AYEP+WAIGTG Sbjct: 120 AQKAGLIPILCVGESKAQRDAGETEQVIVDQVKKGLVNV-DQSNLVIAYEPIWAIGTGDT 178 Query: 176 ATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGAS 235 +A + IR+ L + S++ I YGGS N +N + ++DG LVGGAS Sbjct: 179 CAATEANRVIGLIREQLTN-------SQVTIQYGGSVNANNVDEIMAQPEIDGALVGGAS 231 Query: 236 LKPE-FVDIIN 245 L+P+ F I+N Sbjct: 232 LEPQSFARIVN 242 >4Y9A-A nrPDB Length = 261 Score = 147 bits (372), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 96/254 (37%), Positives = 140/254 (55%), Gaps = 8/254 (3%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN---VEVVICPPATYLDYSVSLVK--KP 57 RT + GN+K+N + V++L A ++ VEV + P T L +LV K Sbjct: 7 RTPLMAGNWKMNLNHLEAIAHVQKLAFALADKDYDAVEVAVLAPFTDLRSVQTLVDGDKL 66 Query: 58 QVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFAL 117 ++ GAQ+ GA+TGE S + + +V +GHSERR Y E D+ + K K A Sbjct: 67 KIKYGAQDISAHDGGAYTGEISGPMLAKLKCTYVAVGHSERRQYHAETDEIVNAKVKAAY 126 Query: 118 GQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLA 175 G+ ILC+GE L+ ++AG ++ Q+ L+++ + +VV+AYEPVWAIGTG Sbjct: 127 KHGLTPILCVGEELDVREAGNHVEHTLAQVEGGLKDLAAEQAESVVIAYEPVWAIGTGKV 186 Query: 176 ATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGAS 235 +DAQ++ A+IR LA + A ++RI YGGS N K D+DG LVGGAS Sbjct: 187 CGADDAQEVCAAIRGKLAELYSQELADKVRIQYGGSVKSGNVAEIMAKPDIDGALVGGAS 246 Query: 236 LKP-EFVDIINSRN 248 L EFV I+ R+ Sbjct: 247 LDSDEFVKIVRFRD 260 >4Y90-A nrPDB Length = 247 Score = 145 bits (365), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 96/240 (40%), Positives = 137/240 (57%), Gaps = 8/240 (3%) Query: 10 NFKLNGSKQSIKEIVERLNTASIP-ENVEVVICPPATYLDYSVSLVKKPQ-VTVGAQNAY 67 N+K+N + + E L T P E V++ + PA LD S P + G Q+ Sbjct: 11 NWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPA--LDLSALAANLPAGIAFGGQDVS 68 Query: 68 LKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCI 127 SGA+TGE S +KD GA V++GHSERR Y E D +A K + A G+ I+C+ Sbjct: 69 AHESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDATVAAKARQAQANGLLPIVCV 128 Query: 128 GETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHAS 187 GE L+ ++ G+ + QL LE V +VVVAYEPVWAIGTG AT +DA+++ A+ Sbjct: 129 GENLDVRERGEHVPQTLAQLRGSLEGVG--ADVVVAYEPVWAIGTGKTATADDAEELAAA 186 Query: 188 IRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFVDIINS 246 IR L + G +A +R+LYGGS N K +V+G LVGGASLK P+ + ++++ Sbjct: 187 IRGALREQYGARAEG-IRVLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGMLDA 245 >2JGQ-A nrPDB Length = 233 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 66/183 (36%), Positives = 99/183 (54%), Gaps = 11/183 (6%) Query: 58 QVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFAL 117 T+G QNAY + GAFTGE + ++++ +++GHSERR+ E F+ +K F Sbjct: 52 HFTLGVQNAYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRTLLKESPSFLKEKFDFFK 111 Query: 118 GQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVK-DWTNVVVAYEPVWAIGTGLAA 176 + ++ CIGE L ++ G V+ L+ LE + ++ N+VVAYEP+WAIGT +A Sbjct: 112 SKNFKIVYCIGEELTTREKG--FKAVKEFLSEQLENIDLNYPNLVVAYEPIWAIGTKKSA 169 Query: 177 TPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 + ED H +++ L K +LYGGS N NA VDG L+G AS Sbjct: 170 SLEDIYLTHGFLKQILNQKTP--------LLYGGSVNTQNAKEILGIDSVDGLLIGSASW 221 Query: 237 KPE 239 + E Sbjct: 222 ELE 224 >3S6D-A nrPDB Length = 310 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 69/218 (31%), Positives = 107/218 (49%), Gaps = 13/218 (5%) Query: 26 RLNTASIPENVEVVICPPATYLDYSVSLV------KKPQVTVGAQNAYLKASGAFTGENS 79 RL A IP+ + + C A ++ +L P + +GAQ+ + + G +TGE S Sbjct: 74 RLLLALIPDFLTIYPCSEAIK-EFESNLAAPQDADTPPPLLLGAQDCFWDSLGPYTGEIS 132 Query: 80 VDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGET-----LEEK 134 ++D+ V LGH+ERR+ F E D+ +A K A QG+ ++CIGE + + Sbjct: 133 PVCLRDMNVSIVELGHAERRAIFGETDQQVARKAAAAADQGLIPLVCIGEVSTLGPIVSE 192 Query: 135 KAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLAS 194 G+ + E Q+ VLE + V+ AYEPVWAIG A + + + IR + Sbjct: 193 AIGRAVGECEAQIRPVLEALPRDAPVIFAYEPVWAIGKPQPARVDHVGAVVSGIRSVI-E 251 Query: 195 KLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 ++ E+RILYGGSA +VDG +G Sbjct: 252 RIDRHRKGEVRILYGGSAGPGLWGPGGLGKEVDGMFLG 289 >1W0M-A nrPDB Length = 226 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 4/68 (5%) Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 + V AQ A ++A GA T S++ IK+ G VIL HSE ++ + +A Sbjct: 57 IPVYAQGADVEAGGAHTAHVSLENIKEAGGSGVILNHSEAPLKLNDLARLVAKAKSL--- 113 Query: 119 QGVGVILC 126 G+ V++C Sbjct: 114 -GLDVVVC 120 >5CSS-A nrPDB Length = 226 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 25/125 (20%) Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQ+ + GA+TG +D + D+G IL HSERR D I + K A Sbjct: 59 AQHVDAEPYGAYTGHVPMDMMIDLGITGSILNHSERR--LPRDT--IINTLKKASKLDFT 114 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLA---ATPE 179 ++LC+ E EE K +++ +AYEP IG ++ A PE Sbjct: 115 IVLCV-ENAEEAKY-----------------FREYEPDFIAYEPRDLIGGDVSVSTAKPE 156 Query: 180 DAQDI 184 +DI Sbjct: 157 IIEDI 161 >2H6R-A nrPDB Length = 219 Score = 35.4 bits (80), Expect = 0.021, Method: Compositional matrix adjust. Identities = 33/137 (24%), Positives = 57/137 (41%), Gaps = 22/137 (16%) Query: 53 LVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADK 112 +V+ + V AQ+ G+ TG + IKD G K ++ HSE+R D + + +K Sbjct: 48 IVENVNIPVYAQHIDNINPGSHTGHILAEAIKDCGCKGTLINHSEKRMLL-ADIEAVINK 106 Query: 113 TKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGT 172 K G+ I+C + KA V + +A EP IGT Sbjct: 107 CK---NLGLETIVCTN-NINTSKA-----------------VAALSPDCIAVEPPELIGT 145 Query: 173 GLAATPEDAQDIHASIR 189 G+ + + + + ++R Sbjct: 146 GIPVSKANPEVVEGTVR 162 >3SQW-A nrPDB Length = 579 Score = 31.6 bits (70), Expect = 0.36, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%) Query: 127 IGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVA----YEPVWAIGT----GLAATP 178 IG T K G ++ + + + E++D N+V+A YEP I + + P Sbjct: 379 IGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEP 438 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRIL 207 ED DI S+ S + + SE RIL Sbjct: 439 EDISDIVISLISSYRSCIKEYRFSERRIL 467 >3I62-A nrPDB Length = 563 Score = 31.2 bits (69), Expect = 0.43, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%) Query: 127 IGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVA----YEPVWAIGT----GLAATP 178 IG T K G ++ + + + E++D N+V+A YEP I + + P Sbjct: 430 IGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEP 489 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRIL 207 ED DI S+ S + + SE RIL Sbjct: 490 EDISDIVISLISSYRSCIKEYRFSERRIL 518 >2RFC-A nrPDB Length = 343 Score = 30.0 bits (66), Expect = 0.93, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 91 VILGHSER-RSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLD 141 V LG + R ++F E D F + + L G+G+ +C+G L +A L+ Sbjct: 259 VYLGSANRDETFFDEPDLFKIGRREMHLAFGIGIHMCLGAPLARLEASIALN 310 >3LGD-A nrPDB Length = 508 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 27/53 (50%) Query: 7 VGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQV 59 +GG LN ++ E + L A + E + +I PP+ + + L+++ QV Sbjct: 20 LGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQV 72 >5D6O-A nrPDB Length = 349 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 22/38 (57%) Query: 170 IGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRIL 207 IG GL+ +P + D S+ KF ++GD ++ R+L Sbjct: 89 IGNGLSVSPANTADDSISMSKFPNVRIGDDVVAQDRLL 126 >5IUJ-C nrPDB Length = 139 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 50 SVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFH 103 +V VKK Q V + + TG + +++KD G K +IL R YF Sbjct: 43 AVDFVKKRQPDVCIMDIEMPGK---TGLEAAEELKDTGCKIIILTTFARPGYFQ 93 >5VU2-M nrPDB Length = 866 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 11/43 (25%) Query: 200 AASELRILYGGS-------ANGSNAVTFKDKADVDGFLVGGAS 235 A+++LR+LY G+ ANG +AVT KD F+VG S Sbjct: 613 ASAKLRVLYQGNNITVTAYANGDHAVTVKDAK----FIVGPMS 651 >1FOB-A nrPDB Length = 334 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 17/145 (11%) Query: 8 GGNFK-LNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNA 66 G ++K LNG Q+++ I+ SI + V V + LDY++ L K+ V + Sbjct: 19 GYSYKNLNGQTQALETILADAGINSIRQRVWVNPSDGSYDLDYNLELAKR--VKAAGMSL 76 Query: 67 YLKASGAFTGENSVDQ-------IKDVGA-KWVILGHS-ERRSYFHEDDKFIADKTKFAL 117 YL + T + DQ D+G KW + ++ E + F E+D D ++ Sbjct: 77 YLDLHLSDTWADPSDQTTPSGWSTTDLGTLKWQLYNYTLEVCNTFAEND---IDIEIISI 133 Query: 118 GQGV--GVILCIGETLEEKKAGKTL 140 G + G++ +GET G L Sbjct: 134 GNEIRAGLLWPLGETSSYSNIGALL 158 >3N42-F nrPDB Length = 473 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 11/43 (25%) Query: 200 AASELRILYGGS-------ANGSNAVTFKDKADVDGFLVGGAS 235 A+++LR+LY G+ ANG +AVT KD F+VG S Sbjct: 151 ASAKLRVLYQGNNITVTAYANGDHAVTVKDAK----FIVGPMS 189 >2XFB-A nrPDB Length = 391 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 11/43 (25%) Query: 200 AASELRILYGGS-------ANGSNAVTFKDKADVDGFLVGGAS 235 A+++LR+LY G+ ANG +AVT KD F+VG S Sbjct: 129 ASAKLRVLYQGNNITVTAYANGDHAVTVKDAK----FIVGPMS 167 >2XFC-A nrPDB Length = 439 Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 11/43 (25%) Query: 200 AASELRILYGGS-------ANGSNAVTFKDKADVDGFLVGGAS 235 A+++LR+LY G+ ANG +AVT KD F+VG S Sbjct: 129 ASAKLRVLYQGNNITVTAYANGDHAVTVKDAK----FIVGPMS 167 >4LDZ-A nrPDB Length = 203 Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 50 SVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFH 103 +V VKK Q V + + TG + +++KD G K +IL R YF Sbjct: 43 AVDFVKKRQPDVCIMDIEMPGK---TGLEAAEELKDTGCKIIILTTFARPGYFQ 93 >3TC8-A nrPDB Length = 309 Score = 27.7 bits (60), Expect = 4.9, Method: Compositional matrix adjust. Identities = 36/146 (24%), Positives = 54/146 (36%), Gaps = 31/146 (21%) Query: 48 DYSVSLVKKPQVTVGAQNAYLKAS-----------GAFTGENSVDQIKDVGAKWVILGHS 96 DY S +K+ V Q A L A G+F ENS + ++ H Sbjct: 52 DYLASELKRFGAKVYQQEAILTAYDGTKLEARNIIGSFDPENS--------KRVLLFAHW 103 Query: 97 ERRSYFHEDDKFIADKTKFAL----GQGVGVILCIGETLEEKKAGKTLDVV--ERQLNAV 150 + R Y D +T G GVG +L I + +K G +D++ + + Sbjct: 104 DSRPYSDHDPDPSKHRTPLDGADDGGSGVGALLEIARQIGQKAPGIGIDIIFFDAEDYGT 163 Query: 151 LEEVKDWTNVVVAYEPVWAIGTGLAA 176 E V D+T W +GT A Sbjct: 164 PEFVTDYT------PDSWCLGTQFWA 183 >1HG3-A nrPDB Length = 225 Score = 27.3 bits (59), Expect = 5.8, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 12/69 (17%) Query: 46 YLDYSVSLVKKPQ------------VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVIL 93 Y + V++V PQ + V AQ+ G+ TG + +K+ GA +L Sbjct: 35 YKETGVTIVVAPQLVDLRMIAESVEIPVFAQHIDPIKPGSHTGHVLPEAVKEAGAVGTLL 94 Query: 94 GHSERRSYF 102 HSE R Sbjct: 95 NHSENRMIL 103 >4A2F-A nrPDB Length = 497 Score = 27.3 bits (59), Expect = 6.1, Method: Compositional matrix adjust. Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 16/56 (28%) Query: 6 FVGGNFKLNGSK----------------QSIKEIVERLNTASIPENVEVVICPPAT 45 F GGNF +NG+ QS +++ + S+P N ++ I PAT Sbjct: 331 FAGGNFTINGASFTPPTVPVLLQILSGAQSAADLLPAGSVYSLPANADIEISLPAT 386 >6CR0-A nrPDB Length = 440 Score = 26.9 bits (58), Expect = 7.2, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 26/57 (45%) Query: 176 ATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 A E A+ + ++RK S+ D A E R+ + GSA + D A G VG Sbjct: 373 AMDEYARTSYPAMRKGWFSRYKDMAKPENRLFFAGSATADGWHEYIDGAIESGIRVG 429 >1XSZ-A nrPDB Length = 356 Score = 26.9 bits (58), Expect = 7.6, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYL 47 RTF FKL G Q I +V+ + A +N +VV A YL Sbjct: 94 RTFL--KTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYL 136 >5JNM-A nrPDB Length = 402 Score = 26.9 bits (58), Expect = 7.7, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 46 YLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSV-DQIKDVGAKWVILGHSERRSYFHE 104 Y+D +++ +TV +AYL +G F G+ +V D +KD + + R E Sbjct: 223 YVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIE------AGLRRVLAE 276 Query: 105 DDKFIADKTKFALGQGVGVI 124 ++I ++ F + G + Sbjct: 277 TSQYITNEFDFTEAEQAGYV 296 >4C7P-A nrPDB Length = 402 Score = 26.9 bits (58), Expect = 7.9, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYL 47 RTF FKL G Q I +V+ + A +N +VV A YL Sbjct: 120 RTFL--KTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYL 162 >2QBW-A nrPDB Length = 195 Score = 26.9 bits (58), Expect = 8.5, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Query: 14 NGSKQSIKEIVER----LNTASIPENVEVVICPPATYL 47 NG+KQ I+ VE+ +S+P N+EVV P + L Sbjct: 84 NGAKQEIRVRVEKDGGSGGVSSVPTNLEVVAATPTSLL 121 >3CH8-A nrPDB Length = 195 Score = 26.6 bits (57), Expect = 9.5, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Query: 14 NGSKQSIKEIVER----LNTASIPENVEVVICPPATYL 47 NG+KQ I+ VE+ +S+P N+EVV P + L Sbjct: 85 NGAKQEIRVRVEKDGGSGGVSSVPTNLEVVAATPTSLL 122 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6NEE-A nrPDB 424 e-119 2I9E-A nrPDB 403 e-113 3TH6-A nrPDB 401 e-112 4POC-A nrPDB 400 e-112 5ZGA-A nrPDB 399 e-112 1I45-A nrPDB 394 e-110 1SW7-A nrPDB 393 e-110 6CG9-A nrPDB 392 e-110 1MO0-A nrPDB 390 e-109 5EYW-A nrPDB 387 e-108 4OBT-A nrPDB 386 e-108 2VXN-A nrPDB 374 e-104 4OHQ-A nrPDB 373 e-104 5CG7-A nrPDB 372 e-104 4MKN-A nrPDB 371 e-103 1CI1-A nrPDB 367 e-102 3KRS-A nrPDB 366 e-102 3Q37-A nrPDB 360 e-100 1LZO-A nrPDB 357 2e-99 1B9B-A nrPDB 357 2e-99 3PF3-A nrPDB 355 1e-98 4Y8F-A nrPDB 351 2e-97 1KV5-A nrPDB 350 3e-97 5UPR-A nrPDB 342 6e-95 1BTM-A nrPDB 342 1e-94 2V5B-A nrPDB 342 1e-94 1TMH-A nrPDB 341 3e-94 4Y96-A nrPDB 339 5e-94 5VWN-A nrPDB 337 4e-93 3UWW-A nrPDB 334 2e-92 5IBX-C nrPDB 332 1e-91 1M6J-A nrPDB 332 1e-91 4Y9A-A nrPDB 331 2e-91 1YYA-A nrPDB 330 4e-91 1TRI-A nrPDB 329 9e-91 2Y70-A nrPDB 322 8e-89 3KXQ-A nrPDB 321 2e-88 5UJW-A nrPDB 315 1e-86 4NVT-A nrPDB 313 5e-86 6BVE-A nrPDB 310 3e-85 1AW2-A nrPDB 306 5e-84 4X22-A nrPDB 306 6e-84 3TA6-A nrPDB 305 9e-84 4G1K-A nrPDB 299 6e-82 4Y90-A nrPDB 279 9e-76 2JGQ-A nrPDB 221 2e-58 3S6D-A nrPDB 214 3e-56 Sequences not found previously or not previously below threshold: 5CSS-A nrPDB 64 6e-11 2H6R-A nrPDB 60 7e-10 1HG3-A nrPDB 58 5e-09 1W0M-A nrPDB 57 7e-09 1E6V-A nrPDB 32 0.22 1DGJ-A nrPDB 31 0.36 1R6V-A nrPDB 31 0.75 3K9D-A nrPDB 29 2.0 2RUS-A nrPDB 29 2.4 3KW2-A nrPDB 29 2.4 6OKK-M nrPDB 29 2.6 6FBZ-A nrPDB 28 3.5 2VOU-A nrPDB 28 3.6 2ZVR-A nrPDB 28 3.8 5FGE-J nrPDB 28 4.4 3WXR-K nrPDB 28 4.4 4NNP-A nrPDB 27 5.0 5LZY-jj nrPDB 27 5.1 6GKI-A nrPDB 27 5.2 4AF1-A nrPDB 27 6.0 3J1E-A nrPDB 27 6.4 5XJN-A nrPDB 27 7.1 5GWE-A nrPDB 27 7.1 6D24-C nrPDB 27 7.8 6HIV-CJ nrPDB 27 8.5 3K6V-A nrPDB 27 9.9 >6NEE-A nrPDB Length = 252 Score = 424 bits (1091), Expect = e-119, Method: Composition-based stats. Identities = 146/250 (58%), Positives = 191/250 (76%), Gaps = 3/250 (1%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ-VT 60 +R FFVGGN+K+NG+ +SIK +VE LN+A + N EVV+ PPA YL ++ S +KKP+ + Sbjct: 3 SRKFFVGGNWKMNGTLESIKALVETLNSAQLDPNTEVVVAPPAIYLPFARSKLKKPKEIQ 62 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQN Y K +GAFTGE S + +KD+G WVILGHSERR+ F E D+ IA+K K+AL QG Sbjct: 63 VAAQNCYTKPNGAFTGEISAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALDQG 122 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQ-LNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPE 179 + VI CIGETLEE++AGKT++VV RQ L A+ +++KDW+NVV+AYEPVWAIGTG ATPE Sbjct: 123 LKVIACIGETLEEREAGKTMEVVARQILKAIADKIKDWSNVVIAYEPVWAIGTGKVATPE 182 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-P 238 AQ++HA++RK+L + + A RI+YGGS N +N + D+DGFLVGGASLK P Sbjct: 183 QAQEVHAALRKWLKENVSPEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLKAP 242 Query: 239 EFVDIINSRN 248 EFVDIIN+R Sbjct: 243 EFVDIINARQ 252 >2I9E-A nrPDB Length = 259 Score = 403 bits (1036), Expect = e-113, Method: Composition-based stats. Identities = 134/248 (54%), Positives = 170/248 (68%), Gaps = 1/248 (0%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 MAR F VGGN+K+NG K+ I EI+ L + + ++ EVV+ PA YL+ + V + Sbjct: 1 MARKFVVGGNWKMNGDKKQINEIIGFLKSGPLNQDTEVVVGVPAIYLELVRTCVPAS-IG 59 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQN Y GAFTGE S IKDVGA WVILGHSERR F E D+ IA+K AL G Sbjct: 60 VAAQNCYKVPKGAFTGEISPAMIKDVGADWVILGHSERRQIFGESDELIAEKVCHALESG 119 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 + VI CIGETLEE++AGKT +VV RQ A+ +V DW+NVV+AYEPVWAIGTG ATP+ Sbjct: 120 LKVIACIGETLEEREAGKTEEVVFRQTKAIAAKVNDWSNVVIAYEPVWAIGTGKTATPQQ 179 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 AQD+H ++R+++ + K + +RI YGGS +N + D+DGFLVGGASLKPEF Sbjct: 180 AQDVHKALRQWICENIDAKVGNSIRIQYGGSVTAANCKELASQPDIDGFLVGGASLKPEF 239 Query: 241 VDIINSRN 248 VDIIN+R Sbjct: 240 VDIINARQ 247 >3TH6-A nrPDB Length = 249 Score = 401 bits (1031), Expect = e-112, Method: Composition-based stats. Identities = 135/247 (54%), Positives = 170/247 (68%), Gaps = 1/247 (0%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 AR F VGGN+K++GSK SI++I L AS+ NVEV++ PA YLDY SL+ P V + Sbjct: 3 ARRFCVGGNWKMHGSKNSIRDICNTLKGASLDPNVEVIVACPAPYLDYCRSLLP-PSVAL 61 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQN Y GAFTGE S IKD G +WVILGHSERR F EDD I +K K AL G+ Sbjct: 62 AAQNCYKVEQGAFTGEISPGMIKDCGGQWVILGHSERRHVFKEDDVLIGEKIKHALESGL 121 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 VI CIGE LE+++AG+T +V RQ+ + VKDW+ VV+AYEPVWAIGTG ATP+ A Sbjct: 122 NVIACIGELLEDREAGRTEEVCFRQIKHIASNVKDWSKVVIAYEPVWAIGTGKTATPDQA 181 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q++H+ +R +L++ + AS++RI YGGS N N K D+DGFLVGGASLKPEFV Sbjct: 182 QEVHSKVRNWLSTNVSADVASKVRIQYGGSVNAGNCKELGRKPDIDGFLVGGASLKPEFV 241 Query: 242 DIINSRN 248 IIN+ Sbjct: 242 QIINAMQ 248 >4POC-A nrPDB Length = 254 Score = 400 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 131/247 (53%), Positives = 168/247 (68%), Gaps = 1/247 (0%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 +R FFVGGN+K+NG KQS+ E++ LN A +P + EVV PP Y+D++ + P++ V Sbjct: 9 SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAV 67 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQN Y +GAFTGE S IKD GA WV+LGHSERR F E D+ I K AL +G+ Sbjct: 68 AAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGL 127 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 GVI CIGE L+E++AG T VV Q + + VKDW+ VV+AYEPVWAIGTG ATP+ A Sbjct: 128 GVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQA 187 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q++H +R +L S + D A RI+YGGS G+ + DVDGFLVGGASLKPEFV Sbjct: 188 QEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFV 247 Query: 242 DIINSRN 248 DIIN++ Sbjct: 248 DIINAKQ 254 >5ZGA-A nrPDB Length = 269 Score = 399 bits (1025), Expect = e-112, Method: Composition-based stats. Identities = 122/244 (50%), Positives = 164/244 (67%), Gaps = 1/244 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FFVGGN+K+NGSK+ +++E L A I N EV++ PPA YL + K + V Sbjct: 25 RKFFVGGNWKMNGSKKENDKLIEMLTHAKIDPNTEVLVAPPALYLPSVREKLDK-RFHVA 83 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN Y SGAFTGE S +KDVG WVILGHSERR E D+ + +KT A+ GV Sbjct: 84 AQNCYKVPSGAFTGEVSPAMLKDVGCDWVILGHSERRHILLETDQLVGEKTAHAISAGVN 143 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 VI CIGE LEE++AGKT +V RQ+ A+ + + W ++V+AYEPVWAIGTG AT + AQ Sbjct: 144 VIACIGEKLEEREAGKTEEVCFRQMEAIRKNLSMWNHIVIAYEPVWAIGTGKTATEQQAQ 203 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVD 242 ++H ++R+++ K+ A +RI+YGGS +N T + DVDGFLVGGASLKP+F++ Sbjct: 204 EVHLAVRRWMEEKVSPAVAKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASLKPDFIE 263 Query: 243 IINS 246 I N+ Sbjct: 264 ICNA 267 >1I45-A nrPDB Length = 248 Score = 394 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 246/248 (99%), Positives = 248/248 (100%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT Sbjct: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 VGAQNAYLKASGAFTGENSVDQIKDVGAK+VILGHSERRSYFHEDDKFIADKTKFALGQG Sbjct: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKYVILGHSERRSYFHEDDKFIADKTKFALGQG 120 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD+TNVVVAYEPVWAIGTGLAATPED Sbjct: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDFTNVVVAYEPVWAIGTGLAATPED 180 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF Sbjct: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 Query: 241 VDIINSRN 248 VDIINSRN Sbjct: 241 VDIINSRN 248 >1SW7-A nrPDB Length = 248 Score = 393 bits (1009), Expect = e-110, Method: Composition-based stats. Identities = 130/246 (52%), Positives = 168/246 (68%), Gaps = 1/246 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FFVGGN+K+NG K+S+ E++ LN A + + EVV P+ YLD++ + ++ V Sbjct: 4 RKFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLD-AKIGVA 62 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN Y GAFTGE S IKD+GA WVILGHSERR F E D+ I K AL +G+G Sbjct: 63 AQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLG 122 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 VI CIGE L+E++AG T VV Q A+ + VKDW+ VV+AYEPVWAIGTG ++TP+ AQ Sbjct: 123 VIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGNSSTPQQAQ 182 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVD 242 ++H +R +L S + D A RI+YGGS G N + DVDGFLVGGASLKPEFVD Sbjct: 183 EVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEFVD 242 Query: 243 IINSRN 248 IIN+++ Sbjct: 243 IINAKH 248 >6CG9-A nrPDB Length = 256 Score = 392 bits (1008), Expect = e-110, Method: Composition-based stats. Identities = 128/249 (51%), Positives = 173/249 (69%), Gaps = 3/249 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN--VEVVICPPATYLDYSVSLVKKPQ 58 M R FFVGGN+K NG+ +++IV+ LN +P + VEVV+ PP +L S +++ Sbjct: 4 MGRKFFVGGNWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQE- 62 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 V AQN ++K GAFTGE S + + ++G WVILGHSERR+ E ++F+ DK +AL Sbjct: 63 FHVAAQNCWVKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALS 122 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATP 178 QG+ VI C+GETLE+++AG T+DVV Q A+ E++KDW+NVVVAYEPVWAIGTG ATP Sbjct: 123 QGLKVIACVGETLEQREAGSTMDVVAAQTKAIAEKIKDWSNVVVAYEPVWAIGTGKVATP 182 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 AQ++HAS+R +L + + A RI+YGGS +N + DVDGFLVGGASLKP Sbjct: 183 AQAQEVHASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKP 242 Query: 239 EFVDIINSR 247 EF+DIIN+ Sbjct: 243 EFIDIINAA 251 >1MO0-A nrPDB Length = 275 Score = 390 bits (1002), Expect = e-109, Method: Composition-based stats. Identities = 133/248 (53%), Positives = 166/248 (66%), Gaps = 1/248 (0%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 + R FFVGGN+K+NG S+ IV LN ++ +V+VV+ PPA YL Y+ S +K V Sbjct: 21 LTRKFFVGGNWKMNGDYASVDGIVTFLNASADNSSVDVVVAPPAPYLAYAKSKLKAG-VL 79 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQN Y GAFTGE S IKD+G +WVILGHSERR F E D IA+KT AL G Sbjct: 80 VAAQNCYKVPKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHALEAG 139 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 + V+ CIGE LEE++AG T DV RQL A++++ W N+V+AYEPVWAIGTG A+ E Sbjct: 140 IKVVFCIGEKLEEREAGHTKDVNFRQLQAIVDKGVSWENIVIAYEPVWAIGTGKTASGEQ 199 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEF 240 AQ++H IR FL K+ A RI+YGGS NA K D+DGFLVGGASLKP+F Sbjct: 200 AQEVHEWIRAFLKEKVSPAVADATRIIYGGSVTADNAAELGKKPDIDGFLVGGASLKPDF 259 Query: 241 VDIINSRN 248 V IIN+R+ Sbjct: 260 VKIINARS 267 >5EYW-A nrPDB Length = 249 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 120/245 (48%), Positives = 162/245 (66%), Gaps = 1/245 (0%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R FFVGGN+K+NG K +I I+ + T + N EVV+ P YL Y+ + + + Sbjct: 5 RKFFVGGNWKMNGDKAAIDGIISFMKTGPLSPNTEVVVGCPQCYLMYTREHMP-ANIGIA 63 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN Y A GAFTGE S +KD G +WVILGHSERR+ F E D+ I++K AL G+ Sbjct: 64 AQNCYKVAKGAFTGEISPAMVKDCGCEWVILGHSERRNVFGEPDQLISEKVGHALEAGLK 123 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 VI CIGE LE+++ +T +VV Q+ A+L + DW+ VV+AYEPVWAIGTG A+PE AQ Sbjct: 124 VIPCIGEKLEDREGNRTQEVVFAQMKALLPNISDWSRVVLAYEPVWAIGTGKTASPEQAQ 183 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVD 242 ++HA +R++L + + A RI+YGGS + N K D+DGFLVGGA+LKP+FV Sbjct: 184 EVHADLRQWLRDNVNAEVAESTRIIYGGSVSAGNCQELAKKGDIDGFLVGGAALKPDFVQ 243 Query: 243 IINSR 247 IIN+R Sbjct: 244 IINAR 248 >4OBT-A nrPDB Length = 257 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 129/250 (51%), Positives = 171/250 (68%), Gaps = 3/250 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN--VEVVICPPATYLDYSVSLVKKPQ 58 MAR FFVGGN+K NG+ + +K+IV LN A +P VEVV+ PP +L S ++ Sbjct: 4 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SD 62 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 V AQN ++K GAFTGE S + + ++ WVILGHSERR+ +E +F+ DK +AL Sbjct: 63 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 122 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATP 178 QG+ VI C+GETLEE++AG T+DVV Q A+ + V +W+NVV+AYEPVWAIGTG A+P Sbjct: 123 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASP 182 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 AQ++H +RK+LA + A+ RI+YGGS NG N +ADVDGFLVGGASLKP Sbjct: 183 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 242 Query: 239 EFVDIINSRN 248 EF+DII + Sbjct: 243 EFIDIIKAAE 252 >2VXN-A nrPDB Length = 251 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 116/245 (47%), Positives = 164/245 (66%), Gaps = 3/245 (1%) Query: 4 TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGA 63 N+K NG+ SI+++V+ N +I +V+ V+ P ++ + ++ P+ + A Sbjct: 6 QPIAAANWKCNGTTASIEKLVQVFNEHTISHDVQCVVAPTFVHIPLVQAKLRNPKYVISA 65 Query: 64 QNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGV 123 QNA K SGAFTGE S+ +KD+G WVILGHSERR+Y+ E D+ +A K A QG V Sbjct: 66 QNAIAK-SGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMV 124 Query: 124 ILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPEDA 181 I CIGETL++++A +T VV Q +A+ ++ W VV+AYEPVWAIGTG ATPE A Sbjct: 125 IACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKVATPEQA 184 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q++H +RK+++ +G A++LRILYGGS N +NA T K D++GFLVGGASLKPEF Sbjct: 185 QEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPEFR 244 Query: 242 DIINS 246 DII++ Sbjct: 245 DIIDA 249 >4OHQ-A nrPDB Length = 256 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 127/246 (51%), Positives = 174/246 (70%), Gaps = 2/246 (0%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 + FFVGGN+K NG+K SI +++ LN+A++ +V+VV+ PP Y+D S + ++ + Sbjct: 4 SGKFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTD-RIDI 62 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 QN+++ GAFTGE SV+Q+KD+G KWVILGHSERR E D+FI K +AL +G+ Sbjct: 63 SGQNSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGL 122 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 GVI CIGE LEE++AGKT DV QL A + V W N+VVAYEPVWAIGTG A+P+ A Sbjct: 123 GVIACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAYEPVWAIGTGKVASPQQA 182 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEF 240 Q++H ++R +L + ++ AS+ RI+YGGS NG N+ + D+DGFLVGGASLK PEF Sbjct: 183 QEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEF 242 Query: 241 VDIINS 246 I+NS Sbjct: 243 ATIVNS 248 >5CG7-A nrPDB Length = 271 Score = 372 bits (955), Expect = e-104, Method: Composition-based stats. Identities = 117/245 (47%), Positives = 164/245 (66%), Gaps = 3/245 (1%) Query: 4 TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGA 63 V N+K NG+ SI+++V+ LN I +V+ V+ P ++ + + P+ V A Sbjct: 26 QPIVAANWKCNGTTASIEKLVQVLNEHQIDHDVQCVVAPSFVHIPMVQAKLCNPKYAVSA 85 Query: 64 QNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGV 123 +NA K SGAFTGE S+ +KD+G WVILGHSERR+Y+ E D +A K A QG V Sbjct: 86 ENAIAK-SGAFTGEVSMPILKDLGVSWVILGHSERRTYYGETDGVVAQKVADAYNQGFMV 144 Query: 124 ILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAATPEDA 181 I CIGETL++++A +T VV Q A+ ++ W+ +V+AYEPVWAIGTG ATPE A Sbjct: 145 IACIGETLQQREANQTAKVVLSQTAAIAAKLPKEAWSQIVLAYEPVWAIGTGKVATPEQA 204 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q++HA +R++++ K+G+ A++LRILYGGS NA T K D++GFLVGGASLKPEF Sbjct: 205 QEVHALLRQWVSEKIGNGVATKLRILYGGSVTAGNAKTLYMKPDINGFLVGGASLKPEFR 264 Query: 242 DIINS 246 DII++ Sbjct: 265 DIIDA 269 >4MKN-A nrPDB Length = 270 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 126/247 (51%), Positives = 176/247 (71%), Gaps = 1/247 (0%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 + FFVGGN+K NGS ++ ++V+ LN +IP V+VV+ PP Y+DY + + + + + Sbjct: 18 SAKFFVGGNWKCNGSVANVAKLVDELNAGTIPRGVDVVVAPPFIYIDYVMQHLDRDKYQL 77 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQNA++ +GAFTGE S +Q+ D G WVILGHSERRS F E ++ +A KT AL G+ Sbjct: 78 SAQNAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAGL 137 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 GVI CIGETLE++ +G V++ Q++A+++EVKDWT VV+AYEPVWAIGTG+ A+PE A Sbjct: 138 GVIACIGETLEQRNSGSVFKVLDAQMDALVDEVKDWTKVVLAYEPVWAIGTGVVASPEQA 197 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEF 240 Q++HA +R++ A KLG A +LRI+YGGS + +N + D+DGFLVGGASLK F Sbjct: 198 QEVHAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGAAF 257 Query: 241 VDIINSR 247 V I N+ Sbjct: 258 VTICNAA 264 >1CI1-A nrPDB Length = 251 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 116/250 (46%), Positives = 164/250 (65%), Gaps = 5/250 (2%) Query: 1 MARTF--FVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ 58 MA N+K NGS+ + ++E LN A+ +V+ V+ P ++ + + + P+ Sbjct: 1 MASKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPK 60 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 + AQNA + SGAFTGE S+ +KD G WV+LGHSERR Y+ E ++ +A+K A Sbjct: 61 FQIAAQNAITR-SGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACA 119 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAA 176 G VI+C+GET EE++AG+T VV QL AV +++ W+ VV+AYEPVWAIGTG A Sbjct: 120 AGFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVA 179 Query: 177 TPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 TP+ AQ++H +R+++ SKLG A++LRILYGGS NA T D++GFLVGGASL Sbjct: 180 TPQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASL 239 Query: 237 KPEFVDIINS 246 KPEFV+II + Sbjct: 240 KPEFVEIIEA 249 >3KRS-A nrPDB Length = 271 Score = 366 bits (940), Expect = e-102, Method: Composition-based stats. Identities = 108/251 (43%), Positives = 156/251 (62%), Gaps = 4/251 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ-- 58 M+R +FVGGNFK NG+K+S+K +++ N EV + P + ++ Sbjct: 22 MSRKYFVGGNFKCNGTKESLKTLIDSFKQVE-SSNSEVYVFPTSLHISLVKEFFGNDHPG 80 Query: 59 -VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFAL 117 +G+QN +GAFTGE S + +KD+ ++GHSERR Y+ E D+ + +K K L Sbjct: 81 VFKIGSQNISCTGNGAFTGEVSCEMLKDMDVDCSLVGHSERRQYYSETDQIVNNKVKKGL 140 Query: 118 GQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAAT 177 G+ ++LCIGE+L E++ GKT DV+++QL L++V D +N+V+AYEP+WAIGTG+ AT Sbjct: 141 ENGLKIVLCIGESLSERETGKTNDVIQKQLTEALKDVSDLSNLVIAYEPIWAIGTGVVAT 200 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 P AQ+ HA IR+++ + +S LRI+YGGS N AD+DGFLVGGASLK Sbjct: 201 PGQAQEAHAFIREYVTRMYNPQVSSNLRIIYGGSVTPDNCNELIKCADIDGFLVGGASLK 260 Query: 238 PEFVDIINSRN 248 P F II S Sbjct: 261 PTFAKIIESAQ 271 >3Q37-A nrPDB Length = 251 Score = 360 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 119/250 (47%), Positives = 169/250 (67%), Gaps = 5/250 (2%) Query: 1 MARTF--FVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ 58 MA N+K NGS+QS+ E+++ N+ SI +V+ V+ P ++ + + + P+ Sbjct: 1 MASKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVAPTFLHIPMTKARLTNPK 60 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 + AQNA + SGAFTGE S+ +KD G WV+LGHSERR+Y+ E ++ +ADK A+ Sbjct: 61 FQIAAQNAITR-SGAFTGEVSLQILKDYGISWVVLGHSERRAYYGETNEIVADKVAAAVA 119 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAA 176 G VI+C+GET EE++AG+T VV QL AV +++ W+ VV+AYEPVWAIGTG A Sbjct: 120 SGFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVA 179 Query: 177 TPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 TP+ AQ++H +R+++ SKLG A++LRILYGGS NA T D++GFLVGGASL Sbjct: 180 TPQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASL 239 Query: 237 KPEFVDIINS 246 KPEFV+II + Sbjct: 240 KPEFVEIIEA 249 >1LZO-A nrPDB Length = 248 Score = 357 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 103/248 (41%), Positives = 161/248 (64%), Gaps = 2/248 (0%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASI-PENVEVVICPPATYLDYSVSLVKKPQV 59 MAR +FV N+K NG+ +SIK + N P ++VV+ P + + D++ L++ + Sbjct: 1 MARKYFVAANWKCNGTLESIKSLTNSFNNLDFDPSKLDVVVFPVSVHYDHTRKLLQ-SKF 59 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 + G QN +G++TGE S + KD+ ++VI+GH ERR YFHE D+ + +K + +L Sbjct: 60 STGIQNVSKFGNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLKN 119 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPE 179 + ++C GE+LE+++ KT++V+ +Q+ A ++ + ++ NV++ YEP+WAIGTG ATPE Sbjct: 120 NLKAVVCFGESLEQREQNKTIEVITKQVKAFVDLIDNFDNVILVYEPLWAIGTGKTATPE 179 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 AQ +H IRK + G+K A+++RILYGGS N N + + D+DGFLVG ASLK Sbjct: 180 QAQLVHKEIRKIVKDTCGEKQANQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASLKES 239 Query: 240 FVDIINSR 247 FVDII S Sbjct: 240 FVDIIKSA 247 >1B9B-A nrPDB Length = 255 Score = 357 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 105/246 (42%), Positives = 153/246 (62%), Gaps = 3/246 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERL-NTASIPENVEVVICPPATYLDYSVSLVKKPQV 59 + R + GN+K++ + K+ V L N + E+V+CPP T L ++ + Sbjct: 1 ITRKLILAGNWKMHKTISEAKKFVSLLVNELHDVKEFEIVVCPPFTALSEVGEILSGRNI 60 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 +GAQN + + GAFTGE S ++++G ++VI+GHSERR F EDD+FI K K L + Sbjct: 61 KLGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLEK 120 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAAT 177 G+ ILC+GETLEE++ G T VVE+Q+ + ++ VV+AYEPVWAIGTG AT Sbjct: 121 GMTPILCVGETLEEREKGLTFCVVEKQVREGFYGLDKEEAKRVVIAYEPVWAIGTGRVAT 180 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 P+ AQ++HA IRK L+ ++ A +RILYGGS N + + D+DG LVGGASLK Sbjct: 181 PQQAQEVHAFIRKLLSEMYDEETAGSIRILYGGSIKPDNFLGLIVQKDIDGGLVGGASLK 240 Query: 238 PEFVDI 243 F+++ Sbjct: 241 ESFIEL 246 >3PF3-A nrPDB Length = 257 Score = 355 bits (912), Expect = 1e-98, Method: Composition-based stats. Identities = 121/248 (48%), Positives = 170/248 (68%), Gaps = 4/248 (1%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 AR F+GGNFK NGS IK V + IP++V+VVI P A +L +++ Q+ + Sbjct: 3 ARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIPDSVDVVIAPSAVHLSTAIAANTSKQLRI 62 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 AQN YL+ +GA+TGE SV+ ++D+G K VI+GHSERR E D+ A K K AL +G+ Sbjct: 63 AAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEKGM 122 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD----WTNVVVAYEPVWAIGTGLAAT 177 VI C+GETL+E+KA +T++V QL A+ +E+ + W VV+AYEPVW+IGTG+ AT Sbjct: 123 TVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVVAT 182 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 PE A+++H +RK+ A K+ + A +RI+YGGSANGSN ++DGFLVGGASLK Sbjct: 183 PEQAEEVHVGLRKWFAEKVAAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGASLK 242 Query: 238 PEFVDIIN 245 PEF+ +I+ Sbjct: 243 PEFMTMID 250 >4Y8F-A nrPDB Length = 251 Score = 351 bits (900), Expect = 2e-97, Method: Composition-based stats. Identities = 99/246 (40%), Positives = 142/246 (57%), Gaps = 3/246 (1%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 RT + GN+K++ + ++VE L EVV+CP LD V+ + VG Sbjct: 5 RTPIIAGNWKMHYTIDEAVKLVEELKPLVKDAKCEVVVCPTFVCLDAVKKAVEGTNIKVG 64 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQN + + GAFTGE + ++ + +VI+GHSERR YF+E D+ K K A + Sbjct: 65 AQNMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHNLT 124 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPED 180 ILC GETLE+++ G T DV++ Q+ A LE + + VV+AYEP+WAIGTG AT + Sbjct: 125 PILCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATSDQ 184 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL-KPE 239 A + A+IR +A G + A ++RI YGGS + K+D+DG LVGGASL + Sbjct: 185 ANETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASLVAAD 244 Query: 240 FVDIIN 245 F I+N Sbjct: 245 FAQIVN 250 >1KV5-A nrPDB Length = 250 Score = 350 bits (899), Expect = 3e-97, Method: Composition-based stats. Identities = 122/247 (49%), Positives = 167/247 (67%), Gaps = 3/247 (1%) Query: 4 TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGA 63 N+K NGS+QS+ E+++ N+ SI +V+ V+ +L + + P+ + A Sbjct: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAA 64 Query: 64 QNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGV 123 QNA K SGAFTGE S+ +KD G W++LGHSERR+Y+ E ++ +ADK A+ G V Sbjct: 65 QNAIAK-SGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMV 123 Query: 124 ILCIGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPEDA 181 I CIGETL+E+++G+T VV Q+ A+ +++K DW VV+AYEPVWAIGTG ATP+ A Sbjct: 124 IACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQA 183 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q+ HA I +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPEFV Sbjct: 184 QEAHALISSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFV 243 Query: 242 DIINSRN 248 DII + Sbjct: 244 DIIKATQ 250 >5UPR-A nrPDB Length = 265 Score = 342 bits (879), Expect = 6e-95, Method: Composition-based stats. Identities = 120/255 (47%), Positives = 167/255 (65%), Gaps = 9/255 (3%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIP-ENVEVVICPPATYLDYSVSLVKKPQVT 60 AR FVGGN+K NG+ +E+V+ LN+A + E V+VV+ PP+ ++ +++P+V Sbjct: 7 ARRGFVGGNWKCNGTTAKTQELVDMLNSAPVSFEQVDVVVAPPSLFISQVQDSLRQPRVQ 66 Query: 61 VGAQNAYLK-ASGAFTGENSVDQIKDVGAKWVILGHSERRSYFH----EDDKFIADKTKF 115 V AQ++ + A GAFTGE S IK+ WV+LGHSERR+ F E ++ +A K + Sbjct: 67 VAAQDSSTQQAYGAFTGELSPKMIKEKNIPWVVLGHSERRAGFGGQPGESNQVVAKKVRA 126 Query: 116 ALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD---WTNVVVAYEPVWAIGT 172 AL +G+ VILCIGETLEE+++G+T V+ QL AV + V + W ++V+AYEPVWAIGT Sbjct: 127 ALNEGLSVILCIGETLEERESGQTQKVLSEQLEAVRQAVPEADAWKSIVIAYEPVWAIGT 186 Query: 173 GLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 G AT AQ+ H IR +LA + K A R++YGGS GSNA + DVDGFLVG Sbjct: 187 GKTATAALAQETHRDIRNWLAQAVSPKVAEATRVIYGGSVKGSNAKELFEGEDVDGFLVG 246 Query: 233 GASLKPEFVDIINSR 247 GASL +FV II++ Sbjct: 247 GASLTGDFVSIIDAA 261 >1BTM-A nrPDB Length = 252 Score = 342 bits (877), Expect = 1e-94, Method: Composition-based stats. Identities = 95/248 (38%), Positives = 140/248 (56%), Gaps = 4/248 (1%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN-VEVVICPPATYLDYSVSLVKKPQVTV 61 R + GN+K++ + + VE + P + V V+C P +LD V + + Sbjct: 1 RKPIIAGNWKMHKTLAEAVQFVEDVKGHVPPADEVISVVCAPFLFLDRLVQAADGTDLKI 60 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 GAQ + GA+TGE S +KD+G +VILGHSERR F E D+ + K A +G+ Sbjct: 61 GAQTMHFADQGAYTGEVSPVMLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRGL 120 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPE 179 I+C GE+LEE++AG+T VV Q+ L + + V+AYEP+WAIGTG ++TPE Sbjct: 121 IPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQAVIAYEPIWAIGTGKSSTPE 180 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP- 238 DA + IR ++ G +AA +RI YGGS N F + +DG LVGGASL+P Sbjct: 181 DANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGPLVGGASLEPA 240 Query: 239 EFVDIINS 246 F+ ++ + Sbjct: 241 SFLQLVEA 248 >2V5B-A nrPDB Length = 244 Score = 342 bits (877), Expect = 1e-94, Method: Composition-based stats. Identities = 108/250 (43%), Positives = 156/250 (62%), Gaps = 12/250 (4%) Query: 1 MARTF--FVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ 58 MA N+K NGS+ + ++E LN A+ +V+ V+ P ++ + + + P+ Sbjct: 1 MASKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVAPTFLHIPMTKARLTNPK 60 Query: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALG 118 + AQNA ++ +KD G WV+LGHSERR Y+ E ++ +A+K A Sbjct: 61 FQIAAQNAGNAD--------ALASLKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACA 112 Query: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAA 176 G VI+C+GET EE++AG+T VV QL AV +++ W+ VV+AYEPVWAIGTG A Sbjct: 113 AGFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVA 172 Query: 177 TPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 TP+ AQ++H +R+++ SKLG A++LRILYGGS NA T D++GFLVGGASL Sbjct: 173 TPQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASL 232 Query: 237 KPEFVDIINS 246 KPEFV+II + Sbjct: 233 KPEFVEIIEA 242 >1TMH-A nrPDB Length = 254 Score = 341 bits (874), Expect = 3e-94, Method: Composition-based stats. Identities = 120/249 (48%), Positives = 155/249 (62%), Gaps = 4/249 (1%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERL-NTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 R V GN+KLNGS+ + E+V L + V I PP Y+D + + + + Sbjct: 2 RHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIML 61 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 GAQN L SGAFTGE S +KD+GA+++I+GHSERR+Y E D+ IA K QG+ Sbjct: 62 GAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGL 121 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLE--EVKDWTNVVVAYEPVWAIGTGLAATPE 179 +LCIGET E +AGKT +V RQ++AVL+ + V+AYEPVWAIGTG +ATP Sbjct: 122 TPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPA 181 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 AQ +H IR +A K+ A ++ I YGGS N SNA + DVDGFLVGGASLKPE Sbjct: 182 QAQAVHKFIRDHIA-KVDANIAEQVIIQYGGSVNASNAAELFAQHDVDGFLVGGASLKPE 240 Query: 240 FVDIINSRN 248 FVDIIN+ Sbjct: 241 FVDIINAAE 249 >4Y96-A nrPDB Length = 255 Score = 339 bits (871), Expect = 5e-94, Method: Composition-based stats. Identities = 100/249 (40%), Positives = 140/249 (56%), Gaps = 3/249 (1%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 R FV GN+K+N + K + + + V V + PP +L ++K V + Sbjct: 6 TRKKFVAGNWKMNTTLAEAKALGAAVAKGVTDDRVTVAVFPPYPWLTAVGEVLKGSPVAL 65 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 GAQ+ + GAFTGE S + + G K+ ++GHSERR E + FI K AL +G+ Sbjct: 66 GAQDVSSEKKGAFTGEVSPAMLLETGCKYALIGHSERRHIIGESETFINHKVHTALEEGL 125 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPE 179 V+LC+GETL E++ G V +RQ+ A + + + +V+AYEPVWAIGTG ATPE Sbjct: 126 SVVLCMGETLAERERGLQERVFQRQVYAACAGLTDEQFGRIVIAYEPVWAIGTGKVATPE 185 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 AQ+ HA +R L GDK A I+YGGS N V + DVDG LVGGASLK + Sbjct: 186 QAQEAHAFVRSKLRLLYGDKIADSTPIVYGGSVTPDNTVGLMSQPDVDGALVGGASLKAD 245 Query: 240 -FVDIINSR 247 F+ I+ + Sbjct: 246 SFLAIVKAA 254 >5VWN-A nrPDB Length = 246 Score = 337 bits (864), Expect = 4e-93, Method: Composition-based stats. Identities = 112/247 (45%), Positives = 155/247 (62%), Gaps = 10/247 (4%) Query: 3 RTFFVGGNFKLN-GSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 RTFFVGGN+K N + Q +++VE LN A + NVEVV+ P +L ++K V Sbjct: 2 RTFFVGGNWKANPKTVQEAEKLVEMLNGAKVEGNVEVVVAAPFVFLPTLQQKLRK-DWKV 60 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 A+N + K +G +V IK G +W ILGHSERR EDD+F+A K KFAL G+ Sbjct: 61 SAENVFTKPNG------TVPMIKSFGIEWTILGHSERRDILKEDDEFLAAKAKFALENGM 114 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPE 179 +I C GE L E++AGK + V Q+ ++ + W +VV+AYEP+WAIGTG A+ + Sbjct: 115 KIIYCCGEHLSEREAGKASEFVSAQIEKMIPAIPAGKWDDVVIAYEPIWAIGTGKVASTQ 174 Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE 239 DAQ++ IR LA+K+G A+++RILYGGS +N DVDGFLVGGASL+ Sbjct: 175 DAQEMCKVIRDILAAKVGADIANKVRILYGGSVKPNNCNELAACPDVDGFLVGGASLEAG 234 Query: 240 FVDIINS 246 F++I+NS Sbjct: 235 FINIVNS 241 >3UWW-A nrPDB Length = 261 Score = 334 bits (857), Expect = 2e-92, Method: Composition-based stats. Identities = 103/249 (41%), Positives = 150/249 (60%), Gaps = 6/249 (2%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQ---V 59 RT + GN+K+N + Q K+ V L T + VE VIC PA LD + VK+ + + Sbjct: 10 RTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGL 69 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 +GAQN Y + +GAFTGE S + D+G K+V++GHSERR FHE D+ I K Sbjct: 70 EIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKH 129 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAAT 177 G+ I+C+GET EE+++GK DVV Q+ + + +VV+AYEP+WAIGTG ++T Sbjct: 130 GMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSST 189 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 EDA ++ A +R+ +A + + RI YGGS +N + + D+DG LVGGASLK Sbjct: 190 SEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLK 249 Query: 238 -PEFVDIIN 245 +FV ++ Sbjct: 250 VEDFVQLLE 258 >5IBX-C nrPDB Length = 255 Score = 332 bits (851), Expect = 1e-91, Method: Composition-based stats. Identities = 98/249 (39%), Positives = 149/249 (59%), Gaps = 4/249 (1%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN-VEVVICPPATYLDYSVSLVKKPQV 59 M+R F+ GN+K+N + + K VE + + + VE I PA L +++ K + Sbjct: 4 MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNL 63 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 V AQN Y + +GAFTGE S +K++G +V++GHSERR YFHE D+ I K K Sbjct: 64 KVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFAN 123 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAAT 177 G+ I+C GE+LE +AGK + V Q++A L + + V+AYEP+WAIGTG +A+ Sbjct: 124 GMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSAS 183 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 +DAQ + +R +A+ G + A ++R+ YGGS N ++ DVDG LVGGASL+ Sbjct: 184 QDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLE 243 Query: 238 PE-FVDIIN 245 E F+ +++ Sbjct: 244 AESFLALLD 252 >1M6J-A nrPDB Length = 261 Score = 332 bits (851), Expect = 1e-91, Method: Composition-based stats. Identities = 110/255 (43%), Positives = 154/255 (60%), Gaps = 11/255 (4%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNT---ASIPENVEVVICPPATYLDYSVSLV---- 54 A F VGGN+K NG+ SI+ + + + A + + VEV++ P Y+ ++ Sbjct: 3 AGKFVVGGNWKCNGTLASIETLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQILAGEA 62 Query: 55 KKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTK 114 + V A+NA+ K SGA+TGE V + D +VILGHSERR FHE ++ +A+K K Sbjct: 63 NGANILVSAENAWTK-SGAYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVAEKVK 121 Query: 115 FALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGT 172 A+ G+ VI CIGET ++ A +T +VV QL A+ + W N+++AYEPVWAIGT Sbjct: 122 VAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVWAIGT 181 Query: 173 GLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 G ATP+ AQ++H IRK++ + + A RI YGGS N +N KAD+DGFLVG Sbjct: 182 GKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDGFLVG 241 Query: 233 GASLK-PEFVDIINS 246 GASL +F IINS Sbjct: 242 GASLDAAKFKTIINS 256 >4Y9A-A nrPDB Length = 261 Score = 331 bits (848), Expect = 2e-91, Method: Composition-based stats. Identities = 95/255 (37%), Positives = 140/255 (54%), Gaps = 8/255 (3%) Query: 2 ARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN---VEVVICPPATYLDYSVSLVKKPQ 58 RT + GN+K+N + V++L A ++ VEV + P T L +LV + Sbjct: 6 TRTPLMAGNWKMNLNHLEAIAHVQKLAFALADKDYDAVEVAVLAPFTDLRSVQTLVDGDK 65 Query: 59 VTV--GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFA 116 + + GAQ+ GA+TGE S + + +V +GHSERR Y E D+ + K K A Sbjct: 66 LKIKYGAQDISAHDGGAYTGEISGPMLAKLKCTYVAVGHSERRQYHAETDEIVNAKVKAA 125 Query: 117 LGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGL 174 G+ ILC+GE L+ ++AG ++ Q+ L+++ + +VV+AYEPVWAIGTG Sbjct: 126 YKHGLTPILCVGEELDVREAGNHVEHTLAQVEGGLKDLAAEQAESVVIAYEPVWAIGTGK 185 Query: 175 AATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGA 234 +DAQ++ A+IR LA + A ++RI YGGS N K D+DG LVGGA Sbjct: 186 VCGADDAQEVCAAIRGKLAELYSQELADKVRIQYGGSVKSGNVAEIMAKPDIDGALVGGA 245 Query: 235 SLKP-EFVDIINSRN 248 SL EFV I+ R+ Sbjct: 246 SLDSDEFVKIVRFRD 260 >1YYA-A nrPDB Length = 250 Score = 330 bits (846), Expect = 4e-91, Method: Composition-based stats. Identities = 99/246 (40%), Positives = 139/246 (56%), Gaps = 3/246 (1%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVG 62 R V GN+K++ + + L P E + P L + ++ + QV G Sbjct: 2 RRVLVAGNWKMHKTPSEARVWFAELKRLLPPLQSEAAVLPAFPILPVAKEVLAETQVGYG 61 Query: 63 AQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVG 122 AQ+ GA+TGE S + D+G ++ I+GHSERR Y E D +A+K K L +G+ Sbjct: 62 AQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEGIT 121 Query: 123 VILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPED 180 ILC+GE LE ++ G+ + RQL LE V +V+AYEPVWAIGTG ATPED Sbjct: 122 PILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATPED 181 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE- 239 A+ +H +IRK L+ + G+ AS +RILYGGS N N +VDG LVGGASL+ E Sbjct: 182 AEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLELES 241 Query: 240 FVDIIN 245 F+ ++ Sbjct: 242 FLALLR 247 >1TRI-A nrPDB Length = 243 Score = 329 bits (843), Expect = 9e-91, Method: Composition-based stats. Identities = 114/247 (46%), Positives = 160/247 (64%), Gaps = 10/247 (4%) Query: 4 TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGA 63 N+K NGS+QS+ E+++ N+ SI +V+ V+ +L + + P+ + A Sbjct: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAA 64 Query: 64 QNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGV 123 QNA ++ +KD G W++LGHSERR+Y+ E ++ +ADK A+ G V Sbjct: 65 QNAGNAD--------ALASLKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMV 116 Query: 124 ILCIGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATPEDA 181 I CIGETL+E+++G+T VV Q+ A+ +++K DW VV+AYEPVWAIGTG ATP+ A Sbjct: 117 IACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQA 176 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFV 241 Q+ HA IR +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKPEFV Sbjct: 177 QEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFV 236 Query: 242 DIINSRN 248 DII + Sbjct: 237 DIIKATQ 243 >2Y70-A nrPDB Length = 245 Score = 322 bits (826), Expect = 8e-89, Method: Composition-based stats. Identities = 114/248 (45%), Positives = 160/248 (64%), Gaps = 14/248 (5%) Query: 4 TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYL---DYSVSLVKKPQVT 60 N+K NGS+QS+ E+++ N+ SI +V+ V+ P+ Y+ + + P+ Sbjct: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVA-PSWYMGAQAMTKERLSHPKFV 63 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 + AQNA ++ +KD G W++L HSERR+Y+ E ++ +ADK A+ G Sbjct: 64 IAAQNAGNAD--------ALASLKDFGISWIVLDHSERRAYYGETNEIVADKVAAAVASG 115 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVK--DWTNVVVAYEPVWAIGTGLAATP 178 VI CIGETL+E+ +G+T VV Q+ A+ +++K DW VV+AYEPVWAIGTG ATP Sbjct: 116 FMVIACIGETLQERSSGRTAVVVLTQITAIAKKLKKADWAKVVIAYEPVWAIGTGKVATP 175 Query: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 + AQ+ HA IR +++SK+G A ELRILYGGS NG NA T + DV+GFLVGGASLKP Sbjct: 176 QQAQEAHALIRSWVSSKVGADVAGELRILYGGSVNGRNARTLYQQRDVNGFLVGGASLKP 235 Query: 239 EFVDIINS 246 EFVDII + Sbjct: 236 EFVDIIKA 243 >3KXQ-A nrPDB Length = 275 Score = 321 bits (822), Expect = 2e-88, Method: Composition-based stats. Identities = 96/245 (39%), Positives = 148/245 (60%), Gaps = 4/245 (1%) Query: 4 TFFVGGNFKLNGSKQSIKEI--VERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 F+ GN+K+NG+ +S+ E+ + ++ + E +IC PAT L + ++ + + Sbjct: 27 RPFIAGNWKMNGTGESLGELRAIAAGISSDLGRLFEALICVPATLLSRAFDILGGENILL 86 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 G QN + G +TG+ S +K+ GA VI+GHSERR+ + E D + K + A G+ Sbjct: 87 GGQNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWRAGL 146 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 ++C+GETLEE+K+ K LDV+ RQL L + N+++AYEPVWA+GTG AT D Sbjct: 147 VALICVGETLEERKSNKVLDVLTRQLEGSLPDGATAENIIIAYEPVWAVGTGNTATSADV 206 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP-EF 240 ++HA I + S+ GD+ A ++R+LYGGS SNA A V+G L+GGASLK +F Sbjct: 207 AEVHAFIHHKMHSRFGDEGA-KIRLLYGGSVKPSNAFELLSTAHVNGALIGGASLKAIDF 265 Query: 241 VDIIN 245 + I + Sbjct: 266 LTICD 270 >5UJW-A nrPDB Length = 253 Score = 315 bits (807), Expect = 1e-86, Method: Composition-based stats. Identities = 97/247 (39%), Positives = 148/247 (59%), Gaps = 6/247 (2%) Query: 6 FVGGNFKLNGSKQSIKEIVERLNTASIP-ENVEVVICPPATYLDYSVSLVKKPQVTVGAQ 64 + GN+K+NG+ SIKE+ ++ V + + P + Y+ +S + + +V VG Q Sbjct: 4 LIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPE-KVGVGLQ 62 Query: 65 NAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVI 124 N GA+TGE S ++D+G ++++GHSERRS F E D+ + K + + + Sbjct: 63 NITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPV 122 Query: 125 LCIGETLEEKKAGKTLDVVERQLNAVLEE--VKDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 +CIGE+L+++++GK V+ QL+ +LE V+ VV+AYEPVWAIGTG+ A+ E Q Sbjct: 123 VCIGESLDDRQSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQIQ 182 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFV 241 + H IR LA K+ ++ A ++I+YGGS NA DVDG L+GGASLK EF Sbjct: 183 ETHQFIRSLLA-KVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEFN 241 Query: 242 DIINSRN 248 +IIN N Sbjct: 242 EIINQAN 248 >4NVT-A nrPDB Length = 262 Score = 313 bits (802), Expect = 5e-86, Method: Composition-based stats. Identities = 107/246 (43%), Positives = 150/246 (60%), Gaps = 4/246 (1%) Query: 4 TFFVGGNFKLNGSKQSIKEI--VERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTV 61 V GN+K+NG +S+ E+ + ++ + ++ VIC PAT L + ++ V + Sbjct: 14 RPLVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGL 73 Query: 62 GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGV 121 G Q+A+ K SGA TG+ S + +K+ GA VILGHSERR+ HE +K I KT+ A G+ Sbjct: 74 GGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGL 133 Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDA 181 I+C+GET E+KA + LDV+ QL+ L + N ++AYEPVWAIGTGL T +D Sbjct: 134 VAIVCVGETASERKAERALDVIGDQLSGSLPDGVTAENTIIAYEPVWAIGTGLTPTVQDV 193 Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEF 240 + HA +R+ L + G K A LR+LYGGS SNA ADVDG LVGGASLK +F Sbjct: 194 RAAHAFMREQLIERFGAKGA-HLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAADF 252 Query: 241 VDIINS 246 + I + Sbjct: 253 LAICET 258 >6BVE-A nrPDB Length = 245 Score = 310 bits (795), Expect = 3e-85, Method: Composition-based stats. Identities = 88/248 (35%), Positives = 139/248 (56%), Gaps = 11/248 (4%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNTA--SIPENVEVVICPPATYLDYSVSLVKKPQVT 60 R + GN+K++ ++ + ++ E+ EVV+C P T L + +V Sbjct: 5 RKIIIAGNWKMHKTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVR 64 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 +GAQN + +ASGA+TGE S + ++G +V++GHSERR YF E D+ + A G Sbjct: 65 LGAQNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLAAQKAG 124 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPED 180 + ILC+GE+ ++ AG+T V+ Q+ L V +N+V+AYEP+WAIGTG + Sbjct: 125 LIPILCVGESKAQRDAGETEQVIVDQVKKGLVNVDQ-SNLVIAYEPIWAIGTGDTCAATE 183 Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPE- 239 A + IR+ L + S++ I YGGS N +N + ++DG LVGGASL+P+ Sbjct: 184 ANRVIGLIREQLTN-------SQVTIQYGGSVNANNVDEIMAQPEIDGALVGGASLEPQS 236 Query: 240 FVDIINSR 247 F I+N + Sbjct: 237 FARIVNFQ 244 >1AW2-A nrPDB Length = 256 Score = 306 bits (785), Expect = 5e-84, Method: Composition-based stats. Identities = 104/240 (43%), Positives = 146/240 (60%), Gaps = 6/240 (2%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERLNT-ASIPENVEVVICPPATYLDYSVSLVK--KPQV 59 R V GN+KLNGSK+ + +++ LN V+V + PPA ++D + + + Sbjct: 2 RHPVVMGNWKLNGSKEMVVDLLNGLNAELEGVTGVDVAVAPPALFVDLAERTLTEAGSAI 61 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQ 119 +GAQN L SGAFTG+ S +K+ GA +I+GHSERR Y E D+F+A K F Sbjct: 62 ILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHAESDEFVAKKFAFLKEN 121 Query: 120 GVGVILCIGETLEEKKAGKTLDVVERQLNAVL--EEVKDWTNVVVAYEPVWAIGTGLAAT 177 G+ +LCIGE+ + +AG+T+ V RQL+AV+ + V+ ++AYEP+WAIGTG AAT Sbjct: 122 GLTPVLCIGESDAQNEAGETMAVCARQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAAT 181 Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK 237 EDAQ IHA IR +A K + A + I YGGS NA + + D+DG LVGGA+L Sbjct: 182 AEDAQRIHAQIRAHIAEK-SEAVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAALD 240 >4X22-A nrPDB Length = 250 Score = 306 bits (784), Expect = 6e-84, Method: Composition-based stats. Identities = 93/241 (38%), Positives = 140/241 (58%), Gaps = 6/241 (2%) Query: 3 RTFFVGGNFKLNGSKQSIKEIVERL--NTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 R + GN+K+N S + + + SI ++ ++ P +L+ +++ V Sbjct: 2 RKTIIAGNWKMNLSLKEAVFLAHSIREKIPSISKDKVSMVFPSTLHLENVSKILEGSSVI 61 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 VGAQN Y AFTGE S DQ+K++G K V++GHSERR + E + F DK +F L Sbjct: 62 VGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLLKNE 121 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKD--WTNVVVAYEPVWAIGTGLAATP 178 V+ C+GETL E+++GKTL+V+ Q+ L+ + ++N+++AYEPVWAIGTG ATP Sbjct: 122 FTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKVATP 181 Query: 179 EDAQDIHASIRKFLASKL--GDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 AQ++H+ IRK ++ + + ILYGGS N + D+DG LVGGAS Sbjct: 182 SQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGGASQ 241 Query: 237 K 237 K Sbjct: 242 K 242 >3TA6-A nrPDB Length = 267 Score = 305 bits (783), Expect = 9e-84, Method: Composition-based stats. Identities = 97/247 (39%), Positives = 143/247 (57%), Gaps = 7/247 (2%) Query: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIP---ENVEVVICPPATYLDYSVSLVKKP 57 M+R + GN+K+N + +V+++ + + V+V + PP T L +LV Sbjct: 1 MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDGD 60 Query: 58 QVTV--GAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKF 115 ++ + GAQ+ SGA+TG+ S + +G +V++GHSERR+Y +EDD +A K Sbjct: 61 KLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAAT 120 Query: 116 ALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTG 173 AL G+ I+CIGE L+ ++AG + QL L + + +VV+AYEPVWAIGTG Sbjct: 121 ALKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGTG 180 Query: 174 LAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGG 233 A+ DAQ++ A+IRK LAS + A +R+LYGGS N N + DVDG LVGG Sbjct: 181 RVASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGG 240 Query: 234 ASLKPEF 240 ASL E Sbjct: 241 ASLDGEH 247 >4G1K-A nrPDB Length = 272 Score = 299 bits (767), Expect = 6e-82, Method: Composition-based stats. Identities = 95/246 (38%), Positives = 147/246 (59%), Gaps = 9/246 (3%) Query: 7 VGGNFKLNGSKQSIKEIVERLNTAS--IPENVEVVICPPATYLDYSVSLVKKPQVTVGAQ 64 V GN+K++G + ++ + + + +NV + +C P YL + + ++ +V+ G+Q Sbjct: 30 VIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQ 89 Query: 65 NAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVI 124 + GA+TGE + + + GA + I+GHSERR+Y E ++ +A K + AL G+ I Sbjct: 90 DVSAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPI 149 Query: 125 LCIGETLEEKKAGKTLDVVERQLNAVLEEV--KDWTNVVVAYEPVWAIGTGLAATPEDAQ 182 +C+GETL E++AG T VV QL+AVL + + +VVAYEPVWAIGTG +AT E AQ Sbjct: 150 VCVGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGKSATAEQAQ 209 Query: 183 DIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP-EFV 241 +HA +R +L K A + +LYGGS NA + D+DG L+GGASLK +F+ Sbjct: 210 QVHAFLRG----RLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKSGDFL 265 Query: 242 DIINSR 247 I + Sbjct: 266 AICRAA 271 >4Y90-A nrPDB Length = 247 Score = 279 bits (714), Expect = 9e-76, Method: Composition-based stats. Identities = 93/243 (38%), Positives = 137/243 (56%), Gaps = 6/243 (2%) Query: 6 FVGGNFKLNGSKQSIKEIVERLNTASIP-ENVEVVICPPATYLDYSVSLVKKPQVTVGAQ 64 + N+K+N + + E L T P E V++ + PA L + + + G Q Sbjct: 7 LLALNWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPALDLSALAANLPAG-IAFGGQ 65 Query: 65 NAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVI 124 + SGA+TGE S +KD GA V++GHSERR Y E D +A K + A G+ I Sbjct: 66 DVSAHESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDATVAAKARQAQANGLLPI 125 Query: 125 LCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDI 184 +C+GE L+ ++ G+ + QL LE V +VVVAYEPVWAIGTG AT +DA+++ Sbjct: 126 VCVGENLDVRERGEHVPQTLAQLRGSLEGVG--ADVVVAYEPVWAIGTGKTATADDAEEL 183 Query: 185 HASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLK-PEFVDI 243 A+IR L + G + A +R+LYGGS N K +V+G LVGGASLK P+ + + Sbjct: 184 AAAIRGALREQYGAR-AEGIRVLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGM 242 Query: 244 INS 246 +++ Sbjct: 243 LDA 245 >2JGQ-A nrPDB Length = 233 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 80/249 (32%), Positives = 119/249 (47%), Gaps = 27/249 (10%) Query: 4 TFFVGGNFK----LNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKP-- 57 T NFK + S +KE+ + L V + P L + Sbjct: 1 TKIAMANFKSAMPIFKSHAYLKELEKTLKPQHFDR---VFVFPDFFGL------LPNSFL 51 Query: 58 QVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFAL 117 T+G QNAY + GAFTGE + ++++ +++GHSERR+ E F+ +K F Sbjct: 52 HFTLGVQNAYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRTLLKESPSFLKEKFDFFK 111 Query: 118 GQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVK-DWTNVVVAYEPVWAIGTGLAA 176 + ++ CIGE L ++ G V+ L+ LE + ++ N+VVAYEP+WAIGT +A Sbjct: 112 SKNFKIVYCIGEELTTREKG--FKAVKEFLSEQLENIDLNYPNLVVAYEPIWAIGTKKSA 169 Query: 177 TPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASL 236 + ED H +++ L K +LYGGS N NA VDG L+G AS Sbjct: 170 SLEDIYLTHGFLKQILNQK--------TPLLYGGSVNTQNAKEILGIDSVDGLLIGSASW 221 Query: 237 KPE-FVDII 244 + E F II Sbjct: 222 ELENFKTII 230 >3S6D-A nrPDB Length = 310 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 69/218 (31%), Positives = 104/218 (47%), Gaps = 11/218 (5%) Query: 25 ERLNTASIPENVEVVICPPATY-----LDYSVSLVKKPQVTVGAQNAYLKASGAFTGENS 79 RL A IP+ + + C A L P + +GAQ+ + + G +TGE S Sbjct: 73 SRLLLALIPDFLTIYPCSEAIKEFESNLAAPQDADTPPPLLLGAQDCFWDSLGPYTGEIS 132 Query: 80 VDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGET-----LEEK 134 ++D+ V LGH+ERR+ F E D+ +A K A QG+ ++CIGE + + Sbjct: 133 PVCLRDMNVSIVELGHAERRAIFGETDQQVARKAAAAADQGLIPLVCIGEVSTLGPIVSE 192 Query: 135 KAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLAS 194 G+ + E Q+ VLE + V+ AYEPVWAIG A + + + IR + Sbjct: 193 AIGRAVGECEAQIRPVLEALPRDAPVIFAYEPVWAIGKPQPARVDHVGAVVSGIRSVI-E 251 Query: 195 KLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVG 232 ++ E+RILYGGSA +VDG +G Sbjct: 252 RIDRHRKGEVRILYGGSAGPGLWGPGGLGKEVDGMFLG 289 >5CSS-A nrPDB Length = 226 Score = 63.7 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 37/158 (23%), Positives = 59/158 (37%), Gaps = 26/158 (16%) Query: 31 SIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKW 90 + E++ P L+ + + AQ+ + GA+TG +D + D+G Sbjct: 30 PVQGKFELIFSPSLLDLEKAAKC---GKFRFFAQHVDAEPYGAYTGHVPMDMMIDLGITG 86 Query: 91 VILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAV 150 IL HSERR D I K A ++LC+ E EE Sbjct: 87 SILNHSERRL---PRDTIINT-LKKASKLDFTIVLCV-ENAEE----------------- 124 Query: 151 LEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASI 188 + +++ +AYEP IG G + +I I Sbjct: 125 AKYFREYEPDFIAYEPRDLIG-GDVSVSTAKPEIIEDI 161 >2H6R-A nrPDB Length = 219 Score = 60.2 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 42/216 (19%), Positives = 79/216 (36%), Gaps = 42/216 (19%) Query: 19 SIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGEN 78 I +I E+++ + + + P L +V+ + V AQ+ G+ TG Sbjct: 20 EIAKIAEKVSE---ESGITIGVAPQFVDLRM---IVENVNIPVYAQHIDNINPGSHTGHI 73 Query: 79 SVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGK 138 + IKD G K ++ HSE+R + + I G+ I+C Sbjct: 74 LAEAIKDCGCKGTLINHSEKRMLLADIEAVINK----CKNLGLETIVC------------ 117 Query: 139 TLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGD 198 T ++ + V + +A EP IGTG+ + + + + ++R Sbjct: 118 TNNINTS------KAVAALSPDCIAVEPPELIGTGIPVSKANPEVVEGTVRAV------K 165 Query: 199 KAASELRILYGGSANGSNAVTFKDKADVDGFLVGGA 234 + ++++L G DV L GA Sbjct: 166 EINKDVKVLCG--------AGISKGEDVKAALDLGA 193 >1HG3-A nrPDB Length = 225 Score = 57.5 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 41/194 (21%), Positives = 68/194 (35%), Gaps = 30/194 (15%) Query: 3 RTFFVGGNFK--LNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 + + NFK + + + EI + V +V+ P L V+ P Sbjct: 5 KEPIIAINFKTYIEATGKRALEIAKAAEKVYKETGVTIVVAPQLVDLRMIAESVEIPVF- 63 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 AQ+ G+ TG + +K+ GA +L HSE R + + A G Sbjct: 64 --AQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHSENRMIL----ADLEAAIRRAEEVG 117 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLA---AT 177 + ++C V + A+ + VA EP IGTG+ A Sbjct: 118 LMTMVC-----------SNNPAVSAAVAALNPDY-------VAVEPPELIGTGIPVSKAK 159 Query: 178 PEDAQDIHASIRKF 191 PE + ++K Sbjct: 160 PEVITNTVELVKKV 173 >1W0M-A nrPDB Length = 226 Score = 57.2 bits (137), Expect = 7e-09, Method: Composition-based stats. Identities = 53/218 (24%), Positives = 78/218 (35%), Gaps = 39/218 (17%) Query: 3 RTFFVGGNFKLNGSKQS--IKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVT 60 R + NFK G E+ + A+ V +V+ P L V P Sbjct: 2 RLPILIINFKAYGEAAGKRAVELAKAAERAARELGVNIVVAPNHLELGLVSQSVDIP--- 58 Query: 61 VGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQG 120 V AQ A ++A GA T S++ IK+ G VIL HSE + +A A G Sbjct: 59 VYAQGADVEAGGAHTAHVSLENIKEAGGSGVILNHSEAPLKLN----DLARLVAKAKSLG 114 Query: 121 VGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAAT--- 177 + V++C + L + V A EP IGTG A + Sbjct: 115 LDVVVCAPDP-----------------RTSLAAAALGPHAV-AVEPPELIGTGRAVSRYK 156 Query: 178 PEDAQDIHASIRKFLAS---------KLGDKAASELRI 206 PE + + + + GD A+ LR+ Sbjct: 157 PEAIVETVGLVSRHFPEVSVITGAGIESGDDVAAALRL 194 >1E6V-A nrPDB Length = 553 Score = 32.1 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 53/165 (32%), Gaps = 19/165 (11%) Query: 4 TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGA 63 F++ G +K + K+ KE +++ + I P V V V Sbjct: 27 KFYIFGGWKQSERKKEFKEWADKIVEERGVPHYNPDIGVPLGQRKLMSYQVSGTDVFVEG 86 Query: 64 QNAYLKASGAFTGENSVDQIKDVGAKWVILG----HS--ERRSYFHEDDKFIA---DKTK 114 + + A D+ + VI+G H ERR + I + Sbjct: 87 DDLTFVNNAAM-----QQMWDDIR-RTVIVGMDTAHRVLERRLGKEVTPETINEYMETLN 140 Query: 115 FALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTN 159 AL G + E + E G T D + + LE + + Sbjct: 141 HALPGG----AVVQEHMVEIHPGLTWDCYAKIITGDLELADEIDD 181 >1DGJ-A nrPDB Length = 907 Score = 31.3 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 29/88 (32%), Gaps = 17/88 (19%) Query: 41 CPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENS-----VDQIKDVGAKWVILGH 95 P +D + + A N Y + +G+ + + Sbjct: 544 FPSEVLMDELAEKLGMDPFELRALNCYREGDTTSSGQIPEVMSLPEMFDKM--------- 594 Query: 96 SERRSYFHEDDKFIADKTKFALGQGVGV 123 R Y+ E K + +++ + +GVGV Sbjct: 595 ---RPYYEESKKRVKERSTAEIKRGVGV 619 >1R6V-A nrPDB Length = 671 Score = 30.6 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 32/108 (29%), Positives = 42/108 (38%), Gaps = 15/108 (13%) Query: 128 GETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAAT-PEDAQDIHA 186 GE L + G V +QL TN++VA + TG+ T P+ + A Sbjct: 128 GEELSNELWGLEAIGVTQQLWEEASG----TNIIVA-----VVDTGVDGTHPDLEGQVIA 178 Query: 187 SIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGA 234 R +L S YGGSA A T K D G +VG A Sbjct: 179 GYRPAFDEELPAGTDSS----YGGSAGTHVAGTIAAKKDGKG-IVGVA 221 >3K9D-A nrPDB Length = 464 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 39/105 (37%), Gaps = 10/105 (9%) Query: 4 TFFVGGNFKLNGSKQS-IKEIVERLNTASIPENVEVVICPPA---TYLDYSVSLVKKPQV 59 F + N +N + + + L ++P + V+I + YS + Sbjct: 289 KFILRPNGSMNPAIVGKSVQHIANLAGLTVPADARVLIAEETKVGAKIPYSREKLAPILA 348 Query: 60 TVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHE 104 A+ + +A E S+D + GA ++ HSE + E Sbjct: 349 FYTAE-TWQEAC-----ELSMDILYHEGAGHTLIIHSEDKEIIRE 387 >2RUS-A nrPDB Length = 490 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 200 AASELRILYGG-SANGSNAVTFKDKADVDGFLVGGASLKP 238 R L+ G S N S + +VDG LV G +KP Sbjct: 152 VPEAYRALFDGPSVNISALWKVLGRPEVDGGLVVGTIIKP 191 >3KW2-A nrPDB Length = 257 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 4/46 (8%) Query: 83 IKDVGAKWVIL---GHSERRSYFHEDDKFIADKT-KFALGQGVGVI 124 + ++G V+ HSERR E + IA K +L VI Sbjct: 99 LVEIGVDEVVFIESEHSERRRIKAERLERIAISAMKQSLKASFPVI 144 >6OKK-M nrPDB Length = 144 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 7/11 (63%), Positives = 9/11 (81%) Query: 164 YEPVWAIGTGL 174 YEP+W IG+G Sbjct: 50 YEPLWLIGSGK 60 >6FBZ-A nrPDB Length = 200 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 122 GVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTN 159 ++ IGETLE+++ G+ + VV + + WT Sbjct: 114 TMLAAIGETLEDEEDGEVMGVVVN-VRKGFYRIGVWTR 150 >2VOU-A nrPDB Length = 397 Score = 28.3 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 17/48 (35%), Gaps = 8/48 (16%) Query: 180 DAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVD 227 Q HA + K K AS R+ +GGS N VD Sbjct: 350 QLQQGHAYLNKV------KKMAS--RLQHGGSFEPGNPAFAFGLPKVD 389 >2ZVR-A nrPDB Length = 290 Score = 27.9 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 27/72 (37%), Gaps = 9/72 (12%) Query: 134 KKAGKTLDVVERQLNAVL---EEVKDWTNVVVAYE----PVWAIGTGLAATPEDAQDIH- 185 +K + V Q + + DW V + E P+ AIGTG A + H Sbjct: 44 RKGMELAKRVGYQAVEIAVRDPSIVDWNEVKILSEELNLPICAIGTGQAYLADGLSLTHP 103 Query: 186 -ASIRKFLASKL 196 IRK ++ Sbjct: 104 NDEIRKKAIERV 115 >5FGE-J nrPDB Length = 198 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 17/41 (41%) Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKD 222 Q + + +R+ LA + + ++ +L GG N Sbjct: 78 QAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 >3WXR-K nrPDB Length = 238 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 17/41 (41%) Query: 182 QDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKD 222 Q + + +R+ LA + + ++ +L GG N Sbjct: 78 QAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 >4NNP-A nrPDB Length = 291 Score = 27.5 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 11/25 (44%) Query: 167 VWAIGTGLAATPEDAQDIHASIRKF 191 +W I T TPE + ++K Sbjct: 205 IWEINTEKQGTPEQMRQAIEFVKKH 229 >5LZY-jj nrPDB Length = 710 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%) Query: 92 ILGHSERRSYFH-EDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDV 142 +LG+ +R+ E + A K FA + ET EE++ G T+DV Sbjct: 309 LLGNINKRTMHKYEQESKKAGKASFAYAWVLD------ETGEERERGVTMDV 354 >6GKI-A nrPDB Length = 198 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 13/28 (46%) Query: 174 LAATPEDAQDIHASIRKFLASKLGDKAA 201 +ATP + A+ R++L G A Sbjct: 62 KSATPAQREAYFAAFREYLKQAYGQALA 89 >4AF1-A nrPDB Length = 416 Score = 27.5 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 11/22 (50%), Positives = 15/22 (68%), Gaps = 1/22 (4%) Query: 222 DKADVDGFLVGGAS-LKPEFVD 242 + ++DG LVGG S K EF+D Sbjct: 218 KRHEIDGILVGGPSPTKDEFLD 239 >3J1E-A nrPDB Length = 553 Score = 27.1 bits (59), Expect = 6.4, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 100 SYFHEDDKFIADKTKFALGQGVGVILC---IGETLEEKKAGKTLDVVERQLNAVLEEVKD 156 + E++ I +K L G VI+C I E + A K + V R + LE++ Sbjct: 274 KFLDEEENLIKEKVDKILATGANVIICQKGIDEVAQSYLAKKGVLAVRRAKKSDLEKLAR 333 Query: 157 WT 158 T Sbjct: 334 AT 335 >5XJN-A nrPDB Length = 455 Score = 27.1 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 12/112 (10%) Query: 46 YLDYSVSLVKKPQVTVGAQNAYLKASGAFTG---------ENSVDQIKDVGAKWVILGHS 96 + + ++++ P++ A + L+ SG+ G E IK+ +++G + Sbjct: 311 HPEQWQAILENPKLIPAAVDEVLRYSGSIVGWRRKALKDTEIGGVAIKEGDGVLLLMGSA 370 Query: 97 ER---RSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVER 145 R R E+ + L G G+ C+G L + +A L+ V R Sbjct: 371 NRDEARFENGEEFDISRANAREHLSFGFGIHYCLGNMLAKLQAKICLEEVTR 422 >5GWE-A nrPDB Length = 405 Score = 27.1 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 12/112 (10%) Query: 46 YLDYSVSLVKKPQVTVGAQNAYLKASGAFTG---------ENSVDQIKDVGAKWVILGHS 96 + + ++++ P++ A + L+ SG+ G E IK+ +++G + Sbjct: 261 HPEQWQAILENPKLIPAAVDEVLRYSGSIVGWRRKALKDTEIGGVAIKEGDGVLLLMGSA 320 Query: 97 ER---RSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVER 145 R R E+ + L G G+ C+G L + +A L+ V R Sbjct: 321 NRDEARFENGEEFDISRANAREHLSFGFGIHYCLGNMLAKLQAKICLEEVTR 372 >6D24-C nrPDB Length = 541 Score = 27.1 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 18/30 (60%) Query: 176 ATPEDAQDIHASIRKFLASKLGDKAASELR 205 A+ E+A+ + A +R + ++ D + ELR Sbjct: 22 ASMENAKKVAAELRGEVCERIPDAVSPELR 51 >6HIV-CJ nrPDB Length = 817 Score = 26.7 bits (58), Expect = 8.5, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 18/43 (41%), Gaps = 5/43 (11%) Query: 181 AQDIHASIRKFLASKLGDKAASELRILYGGSANGS-----NAV 218 A+D+ ++ + +K + R+L GG+ + N Sbjct: 261 AEDVCMFLKDVGRQIVEEKLVAVRRLLQGGAVDPELLAAFNCA 303 >3K6V-A nrPDB Length = 354 Score = 26.7 bits (58), Expect = 9.9, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 16/49 (32%), Gaps = 6/49 (12%) Query: 178 PEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADV 226 PE A A R + +++ YG N N + DV Sbjct: 111 PEYADWYAAFARNQMILAYTNESK------YGDEINTDNWYEILRRPDV 153 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.156 0.499 Lambda K H 0.267 0.0482 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,626,247 Number of Sequences: 36641 Number of extensions: 531125 Number of successful extensions: 1751 Number of sequences better than 10.0: 75 Number of HSP's better than 10.0 without gapping: 118 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 1453 Number of HSP's gapped (non-prelim): 164 length of query: 248 length of database: 10,336,785 effective HSP length: 95 effective length of query: 153 effective length of database: 6,855,890 effective search space: 1048951170 effective search space used: 1048951170 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 58 (26.7 bits)