BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00934 (428 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1VB3-A nrPDB 882 0.0 4F4F-A nrPDB 246 1e-65 1KL7-A nrPDB 213 2e-55 3V7N-A nrPDB 184 9e-47 1E5X-A nrPDB 74 9e-14 6NMX-A nrPDB 57 1e-08 2D1F-A nrPDB 46 3e-05 1UIN-A nrPDB 36 0.026 4E0T-A nrPDB 32 0.42 3PC3-A nrPDB 32 0.75 1HV8-A nrPDB 30 1.8 4BBW-A nrPDB 29 3.4 1YAC-A nrPDB 29 4.6 1M1B-A nrPDB 28 5.2 5XEX-A nrPDB 28 8.8 2NWQ-A nrPDB 28 9.7 >1VB3-A nrPDB Length = 428 Score = 882 bits (2278), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/428 (100%), Positives = 428/428 (100%) Query: 1 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS 60 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS Sbjct: 1 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS 60 Query: 61 AFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTH 120 AFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTH Sbjct: 61 AFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTH 120 Query: 121 IAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETV 180 IAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETV Sbjct: 121 IAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETV 180 Query: 181 AIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQ 240 AIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQ Sbjct: 181 AIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQ 240 Query: 241 LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNA 300 LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNA Sbjct: 241 LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNA 300 Query: 301 MDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRA 360 MDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRA Sbjct: 301 MDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRA 360 Query: 361 LRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAAL 420 LRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAAL Sbjct: 361 LRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAAL 420 Query: 421 RKLMMNHQ 428 RKLMMNHQ Sbjct: 421 RKLMMNHQ 428 >4F4F-A nrPDB Length = 468 Score = 246 bits (628), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 152/451 (33%), Positives = 237/451 (52%), Gaps = 42/451 (9%) Query: 1 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS 60 MK + + + F+ A+ GL ++ GL+ P + P+F+ +I + +V + +L+ Sbjct: 6 MKYVSTRGEAPVLGFSDALLAGLARDGGLYLPQEYPQFTAEQIRALRGKSYVEVALAVLT 65 Query: 61 AFIGDEIPQEILEERVRAAFAF-----PAPVANVESDVGCLELFHGPTLAFKDFGGRFMA 115 F G EIP E VR A+ P+ +++ LELFHGPTLAFKD + +A Sbjct: 66 PFTGGEIPAADFERMVREAYGTFRHDAVCPLVQTDANEFVLELFHGPTLAFKDVAMQLLA 125 Query: 116 QMLTHIAGDKP--VTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTL 173 +M+ ++ + TI+ ATSGDTG A AF G N + IL+P G++SP+Q++ + Sbjct: 126 RMMDYVLAQRGERATIVGATSGDTGGAAIEAFGGRDNTDIFILFPNGRVSPVQQRQMTSS 185 Query: 174 G-GNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQ 232 G N+ ++I+G+FD CQ LVK F+D E AL L+ NSIN +R++ Q+ YYF A Sbjct: 186 GFSNVHALSIEGNFDDCQNLVKGMFNDLEFCDALSLSGVNSINWARIMPQVVYYFTAALS 245 Query: 233 LPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKA 292 L R + +VP+GNFGD+ AG +AK +GLP+++ I ATN ND + R L G + + Sbjct: 246 LGAPDR-AVSFTVPTGNFGDIFAGYVAKRMGLPIEQLIIATNDNDILSRTLESGAYEMRG 304 Query: 293 TQATLSNAMDVSQPNNWPRVEELFR---------RKIWQ-LKELGYAAVD---------- 332 T S +MD+ +N+ R+ LF R + Q LK+ G + Sbjct: 305 VAQTTSPSMDIQISSNFERL--LFEAHGRDAAAVRGLMQGLKQSGGFTISEKPLSAIRSE 362 Query: 333 --------DETTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKE 384 DET L + GY +PH+A+ + R++ + + L TAHPAKF + Sbjct: 363 FSAGRSTVDETAATIESVLSKDGYLLDPHSAIGVKVAREKASGTAPMVVLATAHPAKFPD 422 Query: 385 SVEAILGETLDLPK---ELAERADLPLLSHN 412 +V+A G LP +L +R + + HN Sbjct: 423 AVKAACGVEPQLPAWLCDLMQRKESFTVLHN 453 >1KL7-A nrPDB Length = 514 Score = 213 bits (541), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 160/496 (32%), Positives = 243/496 (48%), Gaps = 88/496 (17%) Query: 13 VSFAQAVTQGLGKNQGLFFPHDLPEFS-LTEIDEMLKLDFVTRSAKILSAFIG-DEIPQE 70 +SF +A+ QGL + GLF P +P+ T ++ KL F + I+ +I +EIP Sbjct: 19 ISFEEAIIQGLATDGGLFIPPTIPQVDQATLFNDWSKLSFQDLAFAIMRLYIAQEEIPDA 78 Query: 71 ILEERVRAAFA-FPAP-----VANVESD---VGCLELFHGPTLAFKDFGGRFMAQMLTHI 121 L++ ++ +++ F + V NV D + LELFHGPT AFKD +F+ + + Sbjct: 79 DLKDLIKRSYSTFRSDEVTPLVQNVTGDKENLHILELFHGPTYAFKDVALQFVGNLFEYF 138 Query: 122 ----------AGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFC 171 K +T++ ATSGDTG+A + G +V V ILYP G+ISP+QE+ Sbjct: 139 LQRTNANLPEGEKKQITVVGATSGDTGSAAIYGLRGKKDVSVFILYPTGRISPIQEEQMT 198 Query: 172 TL-GGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAV 230 T+ N++T+++ G FD CQ +VK F D+E + + NSIN +R+LAQ+ YYF + Sbjct: 199 TVPDENVQTLSVTGTFDNCQDIVKAIFGDKEFNSKHNVGAVNSINWARILAQMTYYFYSF 258 Query: 231 AQLPQETRNQLV-VSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWS 289 Q ++ V VPSGNFGD+ AG AK +GLP+++ ATN ND + RFL G + Sbjct: 259 FQATNGKDSKKVKFVVPSGNFGDILAGYFAKKMGLPIEKLAIATNENDILDRFLKSGLYE 318 Query: 290 -PKATQATLSNAMDVSQPNNWPRVEELFRRKI---------------W--QLKELGYAAV 331 ATLS AMD+ +N+ R+ R+ W +LK G V Sbjct: 319 RSDKVAATLSPAMDILISSNFERLLWYLAREYLANGDDLKAGEIVNNWFQELKTNGKFQV 378 Query: 332 D-----------------DETTQQTMRELKELG-----YTSEPHAAVAYRAL-----RDQ 364 D +E T +T++++ E Y +PH AV A +D Sbjct: 379 DKSIIEGASKDFTSERVSNEETSETIKKIYESSVNPKHYILDPHTAVGVCATERLIAKDN 438 Query: 365 LNPGEYGLFLGTAHPAKFKESVEAILG-------ETLDLPKE------------LAERAD 405 +Y + L TAHPAKF ++V L E LP+E ERAD Sbjct: 439 DKSIQY-ISLSTAHPAKFADAVNNALSGFSNYSFEKDVLPEELKKLSTLKKKLKFIERAD 497 Query: 406 LPLLSHNLPADFAALR 421 + L+ + + + A ++ Sbjct: 498 VELVKNAIEEELAKMK 513 >3V7N-A nrPDB Length = 487 Score = 184 bits (466), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 132/441 (29%), Positives = 213/441 (48%), Gaps = 57/441 (12%) Query: 11 EQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILSAFIGDEIPQE 70 E+ +F+ + GL K+ GL+ P + P+ S E+ L + + +ILS F D+I Sbjct: 17 ERHTFSDILLGGLAKDGGLYLPSEYPQVSADELARWRTLPYADLAFEILSKFC-DDIAAA 75 Query: 71 ILEERVRAAF--------------AFPAPVANVESDVGC----LELFHGPTLAFKDFGGR 112 L R + A P+ + ++ G LEL +GPTLAFKD + Sbjct: 76 DLRAITRRTYTADVYRHARRGGNAADITPLTTLGTENGAPVSLLELSNGPTLAFKDMAMQ 135 Query: 113 FMAQMLTHIAGD--KPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQE-KL 169 + + + + + IL ATSGDTG+A +A G V+V +L P K+S Q ++ Sbjct: 136 LLGNLFEYTLAKHGETLNILGATSGDTGSAAEYAMRGKEGVRVFMLSPHKKMSAFQTAQM 195 Query: 170 FCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEA 229 + NI +A++G FD CQ +VK +D K + + NSIN +R++AQ+ YYF+ Sbjct: 196 YSLQDPNIFNLAVNGVFDDCQDIVKAVSNDHAFKAQQKIGTVNSINWARVVAQVVYYFKG 255 Query: 230 VAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWS 289 + ++ +VPSGNFG++ AG +A+ +GLP+++ + ATN ND + F G + Sbjct: 256 YFAATRSNDERVSFTVPSGNFGNVCAGHIARMMGLPIEKLVVATNENDVLDEFFRTGAYR 315 Query: 290 PKATQATL---SNAMDVSQPNNW------------PRVEELFRR-------------KIW 321 ++ Q T S +MD+S+ +N+ RV +LFR Sbjct: 316 VRSAQDTYHTSSPSMDISKASNFERFVFDLLGRDPARVVQLFRDVEQKGGFDLAASGDFA 375 Query: 322 QLKELGYAAVDDETTQ----QTMRELKELGYTS-EPHAAVAYRALRDQLNPGEYGLFLGT 376 ++ E G+ V +T T+R++ E T + H A + R+ L PG + L T Sbjct: 376 RVAEFGF--VSGRSTHADRIATIRDVFERYRTMIDTHTADGLKVAREHLRPGVPMVVLET 433 Query: 377 AHPAKFKESVEAILGETLDLP 397 A P KF ES+ LG+ P Sbjct: 434 AQPIKFGESIREALGQEPSRP 454 >1E5X-A nrPDB Length = 486 Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 87/345 (25%), Positives = 153/345 (44%), Gaps = 45/345 (13%) Query: 103 TLAFKDFGGRFMAQMLTHIAG-DKPVT-ILTATSGDTGAAVAHAFYGLPNVKVVILYPRG 160 T +FKD G + + + +PV + A++GDT AA++ A+ + ++ P Sbjct: 159 TGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALS-AYCASAGIPSIVFLPAN 217 Query: 161 KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLL 220 KIS Q L + ++ID DFD C L++ E+ L + ANS+N RL Sbjct: 218 KISMAQ--LVQPIANGAFVLSIDTDFDGCMKLIR------EITAELPIYLANSLNSLRLE 269 Query: 221 AQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGL----LAKSLGL--PVKRFIAATN 274 Q E + Q + + ++ VP GN G++ A + + LGL + R + A Sbjct: 270 GQKTAAIEILQQFDWQVPDWVI--VPGGNLGNIYAFYKGFKMCQELGLVDRIPRMVCAQA 327 Query: 275 VNDTVPRFLH-DGQW---SPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAA 330 N P +LH W P T ++A+ + P + R ++ LK+ Sbjct: 328 ANAN-PLYLHYKSGWKDFKPMTASTTFASAIQIGDPVS-------IDRAVYALKKCN-GI 378 Query: 331 VDDETTQQTMRELKELGYTSE---PHAAVAYRA---LRDQ--LNPGEYGLFLGTAHPAKF 382 V++ T ++ M + + T PH VA A LR+Q + P + + + TAH KF Sbjct: 379 VEEATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNQGVIAPTDRTVVVSTAHGLKF 438 Query: 383 KESVEAILGETLDLPKELAERADLPLLSHNLPADFAALRKLMMNH 427 +S I + +P ++ P+ ++ ADF A+ ++ ++ Sbjct: 439 TQS--KIDYHSNAIPDMACRFSNPPV---DVKADFGAVMDVLKSY 478 >6NMX-A nrPDB Length = 354 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 71/275 (25%), Positives = 120/275 (43%), Gaps = 33/275 (12%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 PT +FKD R M + + TI+ A++G+T +A A A+ N+K +++ P GK Sbjct: 56 PTGSFKD---RGMVMAVAKAKEEGNDTIMCASTGNT-SAAAAAYAARANMKCIVIIPNGK 111 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 I+ KL + E +AIDG+FD +V+ E+ +AL NS+N RL Sbjct: 112 IA--FGKLAQAVMYGAEIIAIDGNFDDALKIVRSIC--EKSPIAL----VNSVNPYRLEG 163 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLA-------KSLGLPVKRFIAATN 274 Q FE QL + V+++P GN G+++A LP R A Sbjct: 164 QKTAAFEVCEQLGEAPD---VLAIPVGNAGNISAYWKGFKEYHEKNGTSLPKMRGFEAEG 220 Query: 275 VNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE 334 V + + +P+ T++ A+ + P +W + + ++ E+ DDE Sbjct: 221 SAAIVRNEVIE---NPE----TIATAIRIGNPASWDKAVKAAEESNGKIDEV----TDDE 269 Query: 335 TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGE 369 +E G +EP + + + Q+ GE Sbjct: 270 ILHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGE 304 >2D1F-A nrPDB Length = 360 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 72/278 (25%), Positives = 113/278 (40%), Gaps = 39/278 (14%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 PT +FKD R M +T +L A++G+T A+ A + +L P+GK Sbjct: 64 PTGSFKD---RGMTMAVTDALAHGQRAVLCASTGNTSASAAAYAA-RAGITCAVLIPQGK 119 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 I+ KL + + + IDG+FD C L ++ D ++ NS+N R+ Sbjct: 120 IA--MGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPT-----ISLVNSVNPVRIEG 172 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTA-----------GLLAKSLGLPVKRFI 270 Q FE V L V ++P GN G++TA GL+ K LP R + Sbjct: 173 QKTAAFEIVDVLGTAPD---VHALPVGNAGNITAYWKGYTEYHQLGLIDK---LP--RML 224 Query: 271 AATNVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAA 330 T P L + P + T++ A+ + P +W E + Q K AA Sbjct: 225 -GTQAAGAAPLVLGE----PVSHPETIATAIRIGSPASWTSAVEAQQ----QSKGRFLAA 275 Query: 331 VDDETTQQTMRELKELGYTSEPHAAVAYRALRDQLNPG 368 D+E + G EP +A + L ++ G Sbjct: 276 SDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDG 313 >1UIN-A nrPDB Length = 351 Score = 36.2 bits (82), Expect = 0.026, Method: Compositional matrix adjust. Identities = 81/305 (26%), Positives = 125/305 (40%), Gaps = 47/305 (15%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 PT +FKD R M ++ + A++G+T A+ A + +V+L P G Sbjct: 56 PTGSFKD---RGMTLAVSKAVEGGAQAVACASTGNTAASAAAYAARAGILAIVVL-PAGY 111 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 ++ K+ +L V ++G+FD L ++ E VAL NS+N RL Sbjct: 112 VA--LGKVAQSLVHGARIVQVEGNFDDALRLTQKL--TEAFPVAL----VNSVNPHRLEG 163 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGL--------LAKSLGLP-VKRFIAA 272 Q FE V +L ++P GN G++TA L K+ LP + F AA Sbjct: 164 QKTLAFEVVDELGDAPHYH---ALPVGNAGNITAHWMGYKAYHALGKAKRLPRMLGFQAA 220 Query: 273 TNVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELG--YAA 330 + R P TL+ A+ + P +W + R K +E G A Sbjct: 221 GAAPLVLGR--------PVERPETLATAIRIGNPASW---QGAVRAK----EESGGVIEA 265 Query: 331 VDDETTQQTMREL-KELGYTSEPHAAVA----YRALRD-QLNPGEYGLFLGTAHPAKFKE 384 V DE R L +E G EP +A A ++ LR+ +L P + T H K Sbjct: 266 VTDEEILFAYRYLAREEGIFCEPASAAAMAGVFKLLREGRLEPESTVVLTLTGHGLKDPA 325 Query: 385 SVEAI 389 + E + Sbjct: 326 TAERV 330 >4E0T-A nrPDB Length = 428 Score = 32.3 bits (72), Expect = 0.42, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Query: 163 SPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQ 222 SP ++ CTLGGN+ TV + +F + + AF+ + ++G + N +++ +Q Sbjct: 87 SPGRDVYRCTLGGNM-TVELSQNFQRSGSTTRIAFEPVRYQASVGHDRFNRTSVNAFFSQ 145 Query: 223 I 223 + Sbjct: 146 L 146 >3PC3-A nrPDB Length = 527 Score = 31.6 bits (70), Expect = 0.75, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Query: 99 FHGPTLAFKDFGGRFMAQMLTHIAGDKP-VTILTATSGDTGAAVAHAFYGLPNVKVVILY 157 F P + KD G M Q KP TI+ TSG+TG +A A + K +I+ Sbjct: 85 FLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMAC-AVKGYKCIIVM 143 Query: 158 PRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALV 193 P K+S + TLG I + +D+ + L+ Sbjct: 144 PE-KMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLI 178 >1HV8-A nrPDB Length = 367 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 8/55 (14%) Query: 26 NQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILSAFIGDE--------IPQEIL 72 N+G ++ F L E DEML + F+ KIL+A D+ +P+EIL Sbjct: 139 NRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNACNKDKRILLFSATMPREIL 193 >4BBW-A nrPDB Length = 544 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 17/112 (15%) Query: 91 SDVGCLELFHGPTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPN 150 SDV ++L++G T A +D G + A + +I+ +P L A + A A P+ Sbjct: 71 SDVQAVKLYYGGTEALQDKGKKRFAP-VDYISSHRPGNTLAAIPSYS-IKCAEALQ--PS 126 Query: 151 VKVVILYPRGKISP--------LQEK----LFCTLGGNIETVAIDGDFDACQ 190 KVV L K+ P LQ K LF + +++V IDG C+ Sbjct: 127 AKVV-LKSHYKLFPGINFFWISLQMKPETSLFTKISSELQSVKIDGKEAICE 177 >1YAC-A nrPDB Length = 208 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 195 QAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLT 254 A+D+E+ A+ + I+ ++ ++C F A++ + +E + VV+ SG F ++T Sbjct: 89 NAWDNEDFVKAVKATGKKQLIIAGVVTEVCVAFPALSAI-EEGFDVFVVTDASGTFNEIT 147 >1M1B-A nrPDB Length = 295 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/77 (23%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 334 ETTQ-QTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE 392 +TTQ + M K+L + E H ++ R +++ G +G L + ++S EA + Sbjct: 7 KTTQLKQMLNSKDLEFIMEAHNGLSARIVQEAGFKGIWGSGLSVSAQLGVRDSNEASWTQ 66 Query: 393 TLDLPKELAERADLPLL 409 +++ + +++ +D+P+L Sbjct: 67 VVEVLEFMSDASDVPIL 83 >5XEX-A nrPDB Length = 559 Score = 27.7 bits (60), Expect = 8.8, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 26/47 (55%) Query: 58 ILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTL 104 IL+ + +E+ + I +E++R P + ++S+VG L HG L Sbjct: 300 ILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGL 346 >2NWQ-A nrPDB Length = 272 Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 6/53 (11%) Query: 380 AKFKESVEAILGE------TLDLPKELAERADLPLLSHNLPADFAALRKLMMN 426 + +E ++A+ GE L L ++ +RA + NLP +FA LR L+ N Sbjct: 52 GRREERLQALAGELSAKTRVLPLTLDVRDRAAMSAAVDNLPEEFATLRGLINN 104 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1VB3-A nrPDB 617 e-177 4F4F-A nrPDB 520 e-148 3V7N-A nrPDB 477 e-135 1KL7-A nrPDB 471 e-133 1E5X-A nrPDB 311 4e-85 6NMX-A nrPDB 260 7e-70 2D1F-A nrPDB 247 1e-65 Sequences not found previously or not previously below threshold: 2ZSJ-A nrPDB 195 3e-50 1UIN-A nrPDB 183 2e-46 5X2L-A nrPDB 73 3e-13 3L6C-A nrPDB 54 9e-08 3PC3-A nrPDB 44 1e-04 5MMS-A nrPDB 42 4e-04 4COO-A nrPDB 42 4e-04 1M54-A nrPDB 42 4e-04 2BHS-A nrPDB 42 5e-04 2JC3-A nrPDB 41 8e-04 1PWH-A nrPDB 40 0.002 5OHX-A nrPDB 39 0.003 4I1Y-A nrPDB 39 0.004 5YGR-A nrPDB 39 0.004 5I7O-A nrPDB 39 0.005 2Q3D-A nrPDB 39 0.006 3EUA-A nrPDB 38 0.006 4H27-A nrPDB 38 0.007 5B55-A nrPDB 36 0.034 2EGU-A nrPDB 36 0.039 1VDK-A nrPDB 36 0.039 5XCN-X nrPDB 35 0.052 2PQM-A nrPDB 35 0.059 5XEM-A nrPDB 34 0.088 5J5V-A nrPDB 32 0.57 3V75-A nrPDB 30 2.2 >1VB3-A nrPDB Length = 428 Score = 617 bits (1590), Expect = e-177, Method: Composition-based stats. Identities = 428/428 (100%), Positives = 428/428 (100%) Query: 1 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS 60 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS Sbjct: 1 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS 60 Query: 61 AFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTH 120 AFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTH Sbjct: 61 AFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTH 120 Query: 121 IAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETV 180 IAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETV Sbjct: 121 IAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETV 180 Query: 181 AIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQ 240 AIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQ Sbjct: 181 AIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQ 240 Query: 241 LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNA 300 LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNA Sbjct: 241 LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNA 300 Query: 301 MDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRA 360 MDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRA Sbjct: 301 MDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRA 360 Query: 361 LRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAAL 420 LRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAAL Sbjct: 361 LRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAAL 420 Query: 421 RKLMMNHQ 428 RKLMMNHQ Sbjct: 421 RKLMMNHQ 428 >4F4F-A nrPDB Length = 468 Score = 520 bits (1338), Expect = e-148, Method: Composition-based stats. Identities = 149/449 (33%), Positives = 234/449 (52%), Gaps = 38/449 (8%) Query: 1 MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILS 60 MK + + + F+ A+ GL ++ GL+ P + P+F+ +I + +V + +L+ Sbjct: 6 MKYVSTRGEAPVLGFSDALLAGLARDGGLYLPQEYPQFTAEQIRALRGKSYVEVALAVLT 65 Query: 61 AFIGDEIPQEILEERVRAAFAF-----PAPVANVESDVGCLELFHGPTLAFKDFGGRFMA 115 F G EIP E VR A+ P+ +++ LELFHGPTLAFKD + +A Sbjct: 66 PFTGGEIPAADFERMVREAYGTFRHDAVCPLVQTDANEFVLELFHGPTLAFKDVAMQLLA 125 Query: 116 QMLTHIAGDKP--VTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTL 173 +M+ ++ + TI+ ATSGDTG A AF G N + IL+P G++SP+Q++ + Sbjct: 126 RMMDYVLAQRGERATIVGATSGDTGGAAIEAFGGRDNTDIFILFPNGRVSPVQQRQMTSS 185 Query: 174 G-GNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQ 232 G N+ ++I+G+FD CQ LVK F+D E AL L+ NSIN +R++ Q+ YYF A Sbjct: 186 GFSNVHALSIEGNFDDCQNLVKGMFNDLEFCDALSLSGVNSINWARIMPQVVYYFTAALS 245 Query: 233 LPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKA 292 L + +VP+GNFGD+ AG +AK +GLP+++ I ATN ND + R L G + + Sbjct: 246 LG-APDRAVSFTVPTGNFGDIFAGYVAKRMGLPIEQLIIATNDNDILSRTLESGAYEMRG 304 Query: 293 TQATLSNAMDVSQPNNWPRVE-------ELFRRKIWQ-LKELGYAAVD------------ 332 T S +MD+ +N+ R+ R + Q LK+ G + Sbjct: 305 VAQTTSPSMDIQISSNFERLLFEAHGRDAAAVRGLMQGLKQSGGFTISEKPLSAIRSEFS 364 Query: 333 ------DETTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESV 386 DET L + GY +PH+A+ + R++ + + L TAHPAKF ++V Sbjct: 365 AGRSTVDETAATIESVLSKDGYLLDPHSAIGVKVAREKASGTAPMVVLATAHPAKFPDAV 424 Query: 387 EAILGETLDLPK---ELAERADLPLLSHN 412 +A G LP +L +R + + HN Sbjct: 425 KAACGVEPQLPAWLCDLMQRKESFTVLHN 453 >3V7N-A nrPDB Length = 487 Score = 477 bits (1227), Expect = e-135, Method: Composition-based stats. Identities = 137/483 (28%), Positives = 225/483 (46%), Gaps = 59/483 (12%) Query: 1 MKLYNLKDHN--EQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKI 58 M + + E+ +F+ + GL K+ GL+ P + P+ S E+ L + + +I Sbjct: 5 MNYISTRGAGIGERHTFSDILLGGLAKDGGLYLPSEYPQVSADELARWRTLPYADLAFEI 64 Query: 59 LSAFIGDEIPQEILEERVRAAF--------------AFPAPVANVESDVGC----LELFH 100 LS F D+I L R + A P+ + ++ G LEL + Sbjct: 65 LSKFC-DDIAAADLRAITRRTYTADVYRHARRGGNAADITPLTTLGTENGAPVSLLELSN 123 Query: 101 GPTLAFKDFGGRFMAQMLTHIAGD--KPVTILTATSGDTGAAVAHAFYGLPNVKVVILYP 158 GPTLAFKD + + + + + + IL ATSGDTG+A +A G V+V +L P Sbjct: 124 GPTLAFKDMAMQLLGNLFEYTLAKHGETLNILGATSGDTGSAAEYAMRGKEGVRVFMLSP 183 Query: 159 RGKISPLQE-KLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINIS 217 K+S Q +++ NI +A++G FD CQ +VK +D K + + NSIN + Sbjct: 184 HKKMSAFQTAQMYSLQDPNIFNLAVNGVFDDCQDIVKAVSNDHAFKAQQKIGTVNSINWA 243 Query: 218 RLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVND 277 R++AQ+ YYF+ + ++ +VPSGNFG++ AG +A+ +GLP+++ + ATN ND Sbjct: 244 RVVAQVVYYFKGYFAATRSNDERVSFTVPSGNFGNVCAGHIARMMGLPIEKLVVATNEND 303 Query: 278 TVPRFLHDGQWSPKATQATL---SNAMDVSQPNNWP------------RVEELFRR---- 318 + F G + ++ Q T S +MD+S+ +N+ RV +LFR Sbjct: 304 VLDEFFRTGAYRVRSAQDTYHTSSPSMDISKASNFERFVFDLLGRDPARVVQLFRDVEQK 363 Query: 319 ---------KIWQLKELGYAAVDDETTQ----QTMRELKELGYTS-EPHAAVAYRALRDQ 364 ++ E G+ V +T T+R++ E T + H A + R+ Sbjct: 364 GGFDLAASGDFARVAEFGF--VSGRSTHADRIATIRDVFERYRTMIDTHTADGLKVAREH 421 Query: 365 LNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAALRKLM 424 L PG + L TA P KF ES+ LG+ P LP + A+ ++ + Sbjct: 422 LRPGVPMVVLETAQPIKFGESIREALGQEPSRPAAFDGLEALPQRFEVVDANAQQVKDFI 481 Query: 425 MNH 427 H Sbjct: 482 AAH 484 >1KL7-A nrPDB Length = 514 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 159/507 (31%), Positives = 245/507 (48%), Gaps = 89/507 (17%) Query: 3 LYNLKDHNEQ-VSFAQAVTQGLGKNQGLFFPHDLPEFS-LTEIDEMLKLDFVTRSAKILS 60 + + + + +SF +A+ QGL + GLF P +P+ T ++ KL F + I+ Sbjct: 8 YRSTRSSSPKTISFEEAIIQGLATDGGLFIPPTIPQVDQATLFNDWSKLSFQDLAFAIMR 67 Query: 61 AFIG-DEIPQEILEERVRAAFAF-----PAP-VANVESD---VGCLELFHGPTLAFKDFG 110 +I +EIP L++ ++ +++ P V NV D + LELFHGPT AFKD Sbjct: 68 LYIAQEEIPDADLKDLIKRSYSTFRSDEVTPLVQNVTGDKENLHILELFHGPTYAFKDVA 127 Query: 111 GRFMAQMLTHIA----------GDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG 160 +F+ + + K +T++ ATSGDTG+A + G +V V ILYP G Sbjct: 128 LQFVGNLFEYFLQRTNANLPEGEKKQITVVGATSGDTGSAAIYGLRGKKDVSVFILYPTG 187 Query: 161 KISPLQEKLFCTL-GGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRL 219 +ISP+QE+ T+ N++T+++ G FD CQ +VK F D+E + + NSIN +R+ Sbjct: 188 RISPIQEEQMTTVPDENVQTLSVTGTFDNCQDIVKAIFGDKEFNSKHNVGAVNSINWARI 247 Query: 220 LAQICYYFEAVAQLPQETRNQLV-VSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDT 278 LAQ+ YYF + Q ++ V VPSGNFGD+ AG AK +GLP+++ ATN ND Sbjct: 248 LAQMTYYFYSFFQATNGKDSKKVKFVVPSGNFGDILAGYFAKKMGLPIEKLAIATNENDI 307 Query: 279 VPRFLHDGQWS-PKATQATLSNAMDVSQPNNWPRVEELFRRKIW---------------- 321 + RFL G + ATLS AMD+ +N+ R+ R+ Sbjct: 308 LDRFLKSGLYERSDKVAATLSPAMDILISSNFERLLWYLAREYLANGDDLKAGEIVNNWF 367 Query: 322 -QLKELGYAAVD-----------------DETTQQTMRELKELG-----YTSEPHAAVAY 358 +LK G VD +E T +T++++ E Y +PH AV Sbjct: 368 QELKTNGKFQVDKSIIEGASKDFTSERVSNEETSETIKKIYESSVNPKHYILDPHTAVGV 427 Query: 359 RA-----LRDQLNPGEYGLFLGTAHPAKFKESVEAILG-------ETLDLPKE------- 399 A +D +Y + L TAHPAKF ++V L E LP+E Sbjct: 428 CATERLIAKDNDKSIQY-ISLSTAHPAKFADAVNNALSGFSNYSFEKDVLPEELKKLSTL 486 Query: 400 -----LAERADLPLLSHNLPADFAALR 421 ERAD+ L+ + + + A ++ Sbjct: 487 KKKLKFIERADVELVKNAIEEELAKMK 513 >1E5X-A nrPDB Length = 486 Score = 311 bits (796), Expect = 4e-85, Method: Composition-based stats. Identities = 87/345 (25%), Positives = 153/345 (44%), Gaps = 45/345 (13%) Query: 103 TLAFKDFGGRFMAQMLTHIAG-DKPVT-ILTATSGDTGAAVAHAFYGLPNVKVVILYPRG 160 T +FKD G + + + +PV + A++GDT AA++ A+ + ++ P Sbjct: 159 TGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALS-AYCASAGIPSIVFLPAN 217 Query: 161 KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLL 220 KIS Q L + ++ID DFD C L++ E+ L + ANS+N RL Sbjct: 218 KISMAQ--LVQPIANGAFVLSIDTDFDGCMKLIR------EITAELPIYLANSLNSLRLE 269 Query: 221 AQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGL----LAKSLGL--PVKRFIAATN 274 Q E + Q + + ++ VP GN G++ A + + LGL + R + A Sbjct: 270 GQKTAAIEILQQFDWQVPDWVI--VPGGNLGNIYAFYKGFKMCQELGLVDRIPRMVCAQA 327 Query: 275 VNDTVPRFLH-DGQW---SPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAA 330 N P +LH W P T ++A+ + P + R ++ LK+ Sbjct: 328 ANAN-PLYLHYKSGWKDFKPMTASTTFASAIQIGDPVS-------IDRAVYALKKCN-GI 378 Query: 331 VDDETTQQTMRELKELGYTSE---PHAAVAYRA---LRDQ--LNPGEYGLFLGTAHPAKF 382 V++ T ++ M + + T PH VA A LR+Q + P + + + TAH KF Sbjct: 379 VEEATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNQGVIAPTDRTVVVSTAHGLKF 438 Query: 383 KESVEAILGETLDLPKELAERADLPLLSHNLPADFAALRKLMMNH 427 +S I + +P ++ P+ ++ ADF A+ ++ ++ Sbjct: 439 TQS--KIDYHSNAIPDMACRFSNPPV---DVKADFGAVMDVLKSY 478 >6NMX-A nrPDB Length = 354 Score = 260 bits (665), Expect = 7e-70, Method: Composition-based stats. Identities = 76/365 (20%), Positives = 135/365 (36%), Gaps = 42/365 (11%) Query: 43 IDEMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP 102 + L + ++ D+ P L E P + ++ P Sbjct: 1 MASWKGLIHQYKEFLPVT----DQTPALTLHEGNTPLIHLPKLSEQLGIELHVKTEGVNP 56 Query: 103 TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKI 162 T +FKD R M + + TI+ A++G+T +A A A+ N+K +++ P GKI Sbjct: 57 TGSFKD---RGMVMAVAKAKEEGNDTIMCASTGNT-SAAAAAYAARANMKCIVIIPNGKI 112 Query: 163 SPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQ 222 + KL + E +AIDG+FD +V+ + + NS+N RL Q Sbjct: 113 A--FGKLAQAVMYGAEIIAIDGNFDDALKIVRSICE------KSPIALVNSVNPYRLEGQ 164 Query: 223 ICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLA-------KSLGLPVKRFIAATNV 275 FE QL + V+++P GN G+++A LP R A Sbjct: 165 KTAAFEVCEQLGEAPD---VLAIPVGNAGNISAYWKGFKEYHEKNGTSLPKMRGFEAEGS 221 Query: 276 NDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDET 335 V + + T++ A+ + P +W + + ++ E+ DDE Sbjct: 222 AAIVRNEVIEN-------PETIATAIRIGNPASWDKAVKAAEESNGKIDEV----TDDEI 270 Query: 336 TQQTMRELKELGYTSEPHAAVAYRALRDQLNPGE-----YGLFLGTAHPAKFKESVEAIL 390 +E G +EP + + + Q+ GE + + T + K + I Sbjct: 271 LHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVAVLTGNGLKDPNTAVDIS 330 Query: 391 GETLD 395 Sbjct: 331 EIKPV 335 >2D1F-A nrPDB Length = 360 Score = 247 bits (629), Expect = 1e-65, Method: Composition-based stats. Identities = 72/295 (24%), Positives = 117/295 (39%), Gaps = 34/295 (11%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 PT +FKD R M +T +L A++G+T A+ A + +L P+GK Sbjct: 64 PTGSFKD---RGMTMAVTDALAHGQRAVLCASTGNTSASAAAY-AARAGITCAVLIPQGK 119 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 I+ KL + + + IDG+FD C L ++ D ++ NS+N R+ Sbjct: 120 IA--MGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPT-----ISLVNSVNPVRIEG 172 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLA----KSLGL--PVKRFIAATNV 275 Q FE V L V ++P GN G++TA LGL + R + T Sbjct: 173 QKTAAFEIVDVLGTAPD---VHALPVGNAGNITAYWKGYTEYHQLGLIDKLPRML-GTQA 228 Query: 276 NDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDET 335 P L + P + T++ A+ + P +W E + Q K AA D+E Sbjct: 229 AGAAPLVLGE----PVSHPETIATAIRIGSPASWTSAVEAQQ----QSKGRFLAASDEEI 280 Query: 336 TQQTMRELKELGYTSEPHAAVAYRALRDQLNP-----GEYGLFLGTAHPAKFKES 385 + G EP +A + L ++ G + T + K ++ Sbjct: 281 LAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDT 335 >2ZSJ-A nrPDB Length = 352 Score = 195 bits (496), Expect = 3e-50, Method: Composition-based stats. Identities = 62/314 (19%), Positives = 112/314 (35%), Gaps = 39/314 (12%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 PT +FKD R M ++ ++ A++G+T A+ A ++ +L P+G Sbjct: 58 PTGSFKD---RGMTLAISKAVEAGKRAVICASTGNTSASAAAYAARAG-LRAYVLLPKGA 113 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 ++ KL + + +AI G FD +V++ ++ + NS+N R+ Sbjct: 114 VAI--GKLSQAMIYGAKVLAIQGTFDDALNIVRKIGENF------PVEIVNSVNPYRIEG 165 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLL--------AKSLGLPVKRFIAAT 273 Q FE L + +P GN G++TA K LP A Sbjct: 166 QKTAAFEICDTLGEAPDY---HFIPVGNAGNITAYWKGFKIYYEEGKITKLPRMMGWQAE 222 Query: 274 NVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDD 333 V + P T++ A+ + P +W + + ++ A D Sbjct: 223 GAAPIVKGY-------PIKNPQTIATAIKIGNPYSWKSALKAAQESGGKID----AVSDS 271 Query: 334 ETTQQTMRELKELGYTSEPHAAVAYRALRDQL-----NPGEYGLFLGTAHPAKFKESVEA 388 E G EP +A + L + GE T + K ++ Sbjct: 272 EILYAYKLIASTEGVFCEPASAASVAGLIKLVREGFFKGGEVVTCTLTGNGLKDPDTAIK 331 Query: 389 ILGETLDLPKELAE 402 + E + +P + E Sbjct: 332 VCEEPITVPPDFDE 345 >1UIN-A nrPDB Length = 351 Score = 183 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 68/310 (21%), Positives = 113/310 (36%), Gaps = 35/310 (11%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 PT +FKD R M ++ + A++G+T A+ A + +++ P G Sbjct: 56 PTGSFKD---RGMTLAVSKAVEGGAQAVACASTGNTAASAAAY-AARAGILAIVVLPAGY 111 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 ++ K+ +L V ++G+FD L + +L A + NS+N RL Sbjct: 112 VAL--GKVAQSLVHGARIVQVEGNFDDALRLTQ------KLTEAFPVALVNSVNPHRLEG 163 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLL------AKSLGLPVKRFIAATNV 275 Q FE V +L ++P GN G++TA + A + R + Sbjct: 164 QKTLAFEVVDELGDAPHY---HALPVGNAGNITAHWMGYKAYHALGKAKRLPRML-GFQA 219 Query: 276 NDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDET 335 P L P TL+ A+ + P +W ++ A D+E Sbjct: 220 AGAAPLVLG----RPVERPETLATAIRIGNPASWQGAVRAKEESGGVIE----AVTDEEI 271 Query: 336 TQQTMRELKELGYTSEPHAAVAYRALRDQLNPG----EYGLFLG-TAHPAKFKESVEAIL 390 +E G EP +A A + L G E + L T H K + E + Sbjct: 272 LFAYRYLAREEGIFCEPASAAAMAGVFKLLREGRLEPESTVVLTLTGHGLKDPATAERVA 331 Query: 391 GETLDLPKEL 400 +P L Sbjct: 332 ELPPPVPARL 341 >5X2L-A nrPDB Length = 348 Score = 72.5 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 51/275 (18%), Positives = 97/275 (35%), Gaps = 32/275 (11%) Query: 97 ELFHGPTLAFK-DFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVI 155 ELF T +FK + ++ KP ++T +SG+ G A+ +A L + I Sbjct: 47 ELFQ-KTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYA-AKLEGIPAYI 104 Query: 156 LYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSIN 215 + P+ +P +KL V + ++ + + K+ ++ E + + Sbjct: 105 VVPQ--TAPDCKKLA-IQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHP-----NQE 156 Query: 216 ISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNV 275 + + Q E + Q+P + VP G G L + P + AA Sbjct: 157 PAVIAGQGTIALEVLNQVPLVD----ALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPS 212 Query: 276 NDT------VPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYA 329 N + L + P+ + +++ + N WP + +L Sbjct: 213 NADDCYQSKLKGKLMPNLYPPETIADGVKSSIGL---NTWPIIRDLVDDIF--------T 261 Query: 330 AVDDETTQQTMRELKELGYTSEPHAAVAYRALRDQ 364 +DE T + + EP A V A+ Q Sbjct: 262 VTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQ 296 >3L6C-A nrPDB Length = 339 Score = 54.4 bits (129), Expect = 9e-08, Method: Composition-based stats. Identities = 47/275 (17%), Positives = 93/275 (33%), Gaps = 32/275 (11%) Query: 97 ELFHGPTLAFK-DFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVI 155 ELF T +FK + ++ KP ++T +SG+ G A+ +A L + I Sbjct: 47 ELFQ-KTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYA-AKLEGIPAYI 104 Query: 156 LYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSIN 215 + P+ +P +KL V + ++ + + ++ + E + + Sbjct: 105 VVPQ--TAPNCKKLA-IQAYGASIVYSEPSDESRENVAQRIIQETEGILVHP-----NQE 156 Query: 216 ISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNV 275 + + Q E + Q+P +V G + + P + AA Sbjct: 157 PAVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMVAGIA---ITIKTLKPSVKVYAAEPS 212 Query: 276 NDT------VPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYA 329 N + L P+ + +++ + N WP + +L Sbjct: 213 NADDCYQSKLKGELTPNLHPPETIADGVKSSIGL---NTWPIIRDLVDDVF--------T 261 Query: 330 AVDDETTQQTMRELKELGYTSEPHAAVAYRALRDQ 364 +DE T + + EP A V A+ Q Sbjct: 262 VTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQ 296 >3PC3-A nrPDB Length = 527 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 36/161 (22%), Positives = 67/161 (41%), Gaps = 14/161 (8%) Query: 99 FHGPTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILY 157 F P + KD G R + TI+ TSG+TG +A A + K +I+ Sbjct: 85 FLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMA-CAVKGYKCIIVM 143 Query: 158 PRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSI--N 215 P K+S + TLG I + +D+ + L+ + L + NSI + Sbjct: 144 PE-KMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIY-------VAQQLQRETPNSIVLD 195 Query: 216 ISRLLAQICYYFEA-VAQLPQETRNQL-VVSVPSGNFGDLT 254 R +++ A++ + N++ ++ V +G G ++ Sbjct: 196 QYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTIS 236 >5MMS-A nrPDB Length = 408 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 104/298 (34%), Gaps = 33/298 (11%) Query: 97 ELFHGPTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVI 155 E F+ + KD R + TI+ TSG+TG +A A + +I Sbjct: 110 EFFNA-GGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVR-GYRCII 167 Query: 156 LYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDE-ELKVALGLNSA-NS 213 + P K+S + + LG I + FD+ ++ V A+ + E+ + L+ N+ Sbjct: 168 VMPE-KMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNA 226 Query: 214 INISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAAT 273 N L E + Q + ++ G G +T P R I Sbjct: 227 SNP--LAHYDTTADEILQQCDGKLD---MLVASVGTGGTITGIARKLKEKCPGCRIIGVD 281 Query: 274 NVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDD 333 + P+ T +V + + + + R + + + + ++ Sbjct: 282 PEGSILA--------EPEELNQTEQTTYEV-EGIGYDFIPTVLDRTV--VDKWFKSNDEE 330 Query: 334 ETTQQTMRELKEL---GYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEA 388 T M +E G ++ AVA +A ++ L G+ + + +SV Sbjct: 331 AFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE-LQEGQRCVVI-------LPDSVRN 380 >4COO-A nrPDB Length = 563 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 104/298 (34%), Gaps = 33/298 (11%) Query: 97 ELFHGPTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVI 155 E F+ + KD R + TI+ TSG+TG +A A + +I Sbjct: 132 EFFNA-GGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVR-GYRCII 189 Query: 156 LYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDE-ELKVALGLNSA-NS 213 + P K+S + + LG I + FD+ ++ V A+ + E+ + L+ N+ Sbjct: 190 VMPE-KMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNA 248 Query: 214 INISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAAT 273 N L E + Q + ++ G G +T P R I Sbjct: 249 SNP--LAHYDTTADEILQQCDGKLD---MLVASVGTGGTITGIARKLKEKCPGCRIIGVD 303 Query: 274 NVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDD 333 + P+ T +V + + + + R + + + + ++ Sbjct: 304 PEGSILA--------EPEELNQTEQTTYEV-EGIGYDFIPTVLDRTV--VDKWFKSNDEE 352 Query: 334 ETTQQTMRELKEL---GYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEA 388 T M +E G ++ AVA +A ++ L G+ + + +SV Sbjct: 353 AFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE-LQEGQRCVVI-------LPDSVRN 402 >1M54-A nrPDB Length = 363 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 104/298 (34%), Gaps = 33/298 (11%) Query: 97 ELFHGPTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVI 155 E F+ + KD R + TI+ TSG+TG +A A + +I Sbjct: 67 EFFNA-GGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVR-GYRCII 124 Query: 156 LYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDE-ELKVALGLNSA-NS 213 + P K+S + + LG I + FD+ ++ V A+ + E+ + L+ N+ Sbjct: 125 VMPE-KMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNA 183 Query: 214 INISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAAT 273 N L E + Q + ++ G G +T P R I Sbjct: 184 SNP--LAHYDTTADEILQQCDGKLD---MLVASVGTGGTITGIARKLKEKCPGCRIIGVD 238 Query: 274 NVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDD 333 + P+ T +V + + + + R + + + + ++ Sbjct: 239 PEGSILA--------EPEELNQTEQTTYEV-EGIGYDFIPTVLDRTV--VDKWFKSNDEE 287 Query: 334 ETTQQTMRELKEL---GYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEA 388 T M +E G ++ AVA +A ++ L G+ + + +SV Sbjct: 288 AFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE-LQEGQRCVVI-------LPDSVRN 337 >2BHS-A nrPDB Length = 303 Score = 41.7 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 11/123 (8%) Query: 86 VANVESDVGC---LELF-HGPTLAFKDFGGRFMAQMLTHIAGDKP-VTILTATSGDTGAA 140 + + D G L+L + P + KD M KP ++ ATSG+TG A Sbjct: 16 LQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIA 75 Query: 141 VAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETVAIDGD--FDACQALVKQAFD 198 +A L ++ +L P QE+ E + + + + + L + + Sbjct: 76 LAM-IAALKGYRMKLLMPDN---MSQERRAAMRAYGAELILVTKEQGMEGARDLALEMAN 131 Query: 199 DEE 201 E Sbjct: 132 RGE 134 >2JC3-A nrPDB Length = 303 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 38/105 (36%), Gaps = 7/105 (6%) Query: 100 HGPTLAFKDFGGRFMAQMLTHIAGDKP-VTILTATSGDTGAAVAHAFYGLPNVKVVILYP 158 + P + KD M KP ++ ATSG+TG A+A L ++ +L P Sbjct: 34 NNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAM-IAALKGYRMKLLMP 92 Query: 159 RGKISPLQEKLFCTLGGNIETVAIDGD--FDACQALVKQAFDDEE 201 QE+ E + + + + + L + E Sbjct: 93 DN---MSQERRAAMRAYGAELILVTKEQGMEGARDLALAMSERGE 134 >1PWH-A nrPDB Length = 327 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 33/100 (33%), Gaps = 7/100 (7%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 P+ +FK R + + A + +++G+ G A A+A + I+ P Sbjct: 36 PSGSFK---IRGIGHLCKMKAKQGCKHFVCSSAGNAGMATAYAAR-RLGLPATIVVPSTT 91 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEE 201 + E+L + D L K + Sbjct: 92 PALTIERL---KNEGATVEVVGEMLDEAIQLAKALEKNNP 128 >5OHX-A nrPDB Length = 504 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 29/83 (34%), Gaps = 5/83 (6%) Query: 99 FHGPTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILY 157 F P + KD R + TI+ TSG+TG +A A K +I+ Sbjct: 70 FLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVR-GYKCIIVM 128 Query: 158 PRGKISPLQEKLFCTLGGNIETV 180 P EK+ + + Sbjct: 129 PEK---MSDEKISTLYALGAKII 148 >4I1Y-A nrPDB Length = 314 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 6/90 (6%) Query: 96 LELFHGPTLAFKDFGGRFMAQMLTHIAGDKPVT-ILTATSGDTGAAVAHAFYGLPNVKVV 154 LE F+ P + KD G M KP T IL TSG+TG A+A K V Sbjct: 38 LESFN-PAGSIKDRIGVAMIDAAEKAGLIKPDTIILEPTSGNTGIALAMVSAAR-GYKCV 95 Query: 155 ILYPRGKISPLQEKLFCTLGGNIETVAIDG 184 + P + E+ E V G Sbjct: 96 LTMPD---TMSIERRMLLRAYGAELVLTPG 122 >5YGR-A nrPDB Length = 404 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 50/154 (32%), Gaps = 9/154 (5%) Query: 125 KPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETVAIDG 184 K +TAT G+ G VA A +K V+ P+G S ++ + E D Sbjct: 116 KDCVFVTATDGNHGRGVAWA-AEQLGLKAVVYMPKGS-SLIRAENIR--HHGAECTITDL 171 Query: 185 DFDACQALVKQAFDDEELKVALGLN--SANSINISRLLAQICYYFEAVAQLPQET---RN 239 ++D L + + + I + + EA QL + Sbjct: 172 NYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPT 231 Query: 240 QLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAAT 273 L++ G+F G + + + I Sbjct: 232 HLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVE 265 >5I7O-A nrPDB Length = 326 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 28/110 (25%), Positives = 42/110 (38%), Gaps = 3/110 (2%) Query: 102 PTLAFKDF-GGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG 160 PT + KD R + Q TIL TSG+TG ++A A L +++ + P Sbjct: 49 PTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAAR-LKGYRLICVMPEN 107 Query: 161 KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNS 210 S + +L G I A +G + A K+ V L Sbjct: 108 -TSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYG 156 >2Q3D-A nrPDB Length = 313 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 96 LELFHGPTLAFKDFGGRFMAQMLTHIAGDKPVTI-LTATSGDTGAAVAHAFYGLPNVKVV 154 LE F+ P + KD G M Q KP TI L TSG+TG A+A + V Sbjct: 37 LEFFN-PANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAAR-GYRCV 94 Query: 155 ILYPRGKISPLQEKLFCTLGGNIETVAIDG 184 + P + E+ E + G Sbjct: 95 LTMPE---TMSLERRMLLRAYGAELILTPG 121 >3EUA-A nrPDB Length = 329 Score = 38.3 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 24/150 (16%), Positives = 53/150 (35%), Gaps = 9/150 (6%) Query: 122 AGDKPVTILTATSGDTGAA--VAHAFYGLPNVKVVILY-PRGKISPLQEKLFCTL-GGNI 177 G+K + IL + SG+T A G + + + + P ++ QE + Sbjct: 72 LGEKSLVILCSHSGNTPETVKAAAFARGKGALTIAMTFKPESPLA--QEAQYVAQYDWGD 129 Query: 178 ETVAIDGDFDACQALVKQAFDDEE--LKVALGLNSANSINISRLLAQICYYFEAVAQLPQ 235 E +AI+ ++ +V E K + + + A A Sbjct: 130 EALAINTNYGVLYQIVFGTLQVLENNTKFEQAIEGLDQLQAVYEKALKQEADNAKQFAKA 189 Query: 236 ETRNQLVVSVPSG-NFGDLTAGLLAKSLGL 264 + ++ ++ SG N+G + + + + Sbjct: 190 HEKESIIYTMASGANYGVAYSYSICILMEM 219 >4H27-A nrPDB Length = 364 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 47/312 (15%), Positives = 82/312 (26%), Gaps = 34/312 (10%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 P+ +FK R + A + ++SG+ G A A+A L V I+ P Sbjct: 72 PSGSFK---IRGIGHFCKRWAKQGCAHFVCSSSGNAGMAAAYAARQL-GVPATIVVPGTT 127 Query: 162 ISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLA 221 + E+L + D L K + V + + Sbjct: 128 PALTIERL---KNEGATVKVVGELLDEAFELAKALAKNNPGWVYIPPFD----DPLIWEG 180 Query: 222 QICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLG-LPVKRFIAATNVNDTVP 280 E L ++ + G + GL G +P + A Sbjct: 181 HASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGWGDVP----VIAMETFGAHS 236 Query: 281 RFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTM 340 + S A + + +LF+ D E Sbjct: 237 FHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI----FSEVISDQEAVAAIE 292 Query: 341 RELKELGYTSEPHAAVAYRALRDQ----------LNPGEYGLFLGTAHPAKFK----ESV 386 + + + EP A A+ L L + + ++ Sbjct: 293 KFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCGGSNISLAQLRAL 352 Query: 387 EAILGETLDLPK 398 + LG T LPK Sbjct: 353 KEQLGMTNRLPK 364 >5B55-A nrPDB Length = 340 Score = 35.9 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 40/101 (39%), Gaps = 4/101 (3%) Query: 103 TLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGK 161 T + KD + + K I+ ATSG+TG A + A + V+I P Sbjct: 46 TGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFS-AMGAILGHPVIIYMPDW- 103 Query: 162 ISPLQEKLFCTLGGNIETVA-IDGDFDACQALVKQAFDDEE 201 +S ++ L + G I V+ +G F K+ + Sbjct: 104 MSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNP 144 >2EGU-A nrPDB Length = 308 Score = 35.6 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 38/183 (20%), Positives = 56/183 (30%), Gaps = 27/183 (14%) Query: 65 DEIPQEILEERVRAAFAFPAPVANVESDVGCLEL-FHGPTLAFKDFGGRFMAQMLTHIAG 123 + P L V A L+L F P + KD M + Sbjct: 13 GDTPAVKLNRIVDEDSADV-----------YLKLEFMNPGSSVKDRIALAMIEAAEKAGK 61 Query: 124 DKP-VTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETVAI 182 KP TI+ TSG+TG +A K V++ P + E+ E V Sbjct: 62 LKPGDTIVEPTSGNTGIGLAMVAAAK-GYKAVLVMPD---TMSLERRNLLRAYGAELVLT 117 Query: 183 DGDFDACQALVKQAFDDEELKVALGLNS----ANSINISRLLAQICYYFEAVAQLPQETR 238 G Q + EEL G N N + ++ E V Q+ + Sbjct: 118 PG----AQGMRGAIAKAEELVREHGYFMPQQFKNEANPE--IHRLTTGKEIVEQMGDQLD 171 Query: 239 NQL 241 + Sbjct: 172 AFV 174 >1VDK-A nrPDB Length = 466 Score = 35.6 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 51/264 (19%), Positives = 86/264 (32%), Gaps = 49/264 (18%) Query: 65 DEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTHIAGD 124 E+P+EI + ++AA V + D H P + F+ G + + + Sbjct: 64 GELPEEIAKAIIQAA----EEVVQGKWDD------HFPLVVFQTGSGTQTNMNVNEVIAN 113 Query: 125 KPVTILTATSG----------DTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLG 174 + IL G + G + F V V + ++ P E L T Sbjct: 114 RASEILGKPLGSKYAHPNDHVNRGQSSNDTFPTAMYVAVALAL-HQRLYPAVEGLIRTFT 172 Query: 175 GNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSI-NISRLLAQICYYFEAVAQL 233 + FD + + D A+ + I + + AQ+ AV ++ Sbjct: 173 AKAQA------FDQIVKVGRTHLMD-----AVPITLGQEIGSWA---AQLKTTLAAVKEM 218 Query: 234 PQETRNQLVVSVPSGN-------FGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDG 286 + N + G FG+L A LA+ GLP + N HD Sbjct: 219 EKGLYNLAIGGTAVGTGLNAHPRFGELVAKYLAEETGLPFR-----VAENRFAALAAHDE 273 Query: 287 QWSPKATQATLSNA-MDVSQPNNW 309 + TL+ A M + W Sbjct: 274 LVNVMGAIRTLAGALMKIGNDVRW 297 >5XCN-X nrPDB Length = 350 Score = 35.2 bits (79), Expect = 0.052, Method: Composition-based stats. Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 9/80 (11%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDKPVT----ILTATSGDTGAAVAHAFYGLPNVKVVILY 157 P+ + K R A M+ D +T I+ ATSG+TG A+A+ K+ + Sbjct: 71 PSYSVK---CRIGANMVWQAEKDGTLTKGKEIVDATSGNTGIALAYVAAAR-GYKITLTM 126 Query: 158 PRGKISPLQEKLFCTLGGNI 177 P +S +++L C LG N+ Sbjct: 127 PE-TMSLERKRLLCGLGVNL 145 >2PQM-A nrPDB Length = 343 Score = 35.2 bits (79), Expect = 0.059, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 6/90 (6%) Query: 96 LELFHGPTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVV 154 LE F+ P + KD G + Q + + I+ +TSG+TG A+ A + +V Sbjct: 48 LEYFN-PMSSVKDRVGFNIVYQAIKDGRLKPGMEIIESTSGNTGIALCQA-GAVFGYRVN 105 Query: 155 ILYPRGKISPLQEKLFCTLGGNIETVAIDG 184 I P + E+ E + +G Sbjct: 106 IAMPS---TMSVERQMIMKAFGAELILTEG 132 >5XEM-A nrPDB Length = 310 Score = 34.4 bits (77), Expect = 0.088, Method: Composition-based stats. Identities = 51/289 (17%), Positives = 92/289 (31%), Gaps = 34/289 (11%) Query: 102 PTLAFKD-FGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG 160 P + KD + + + DK I+ ATSG+TG +A + N K+ I+ P Sbjct: 41 PGRSTKDRIALKMIEEAEKEGLIDKDTVIIEATSGNTGIGLAM-ICAVKNYKLKIVMPD- 98 Query: 161 KISPLQEKLFCTLGGNIETVAIDGDF--DACQALVKQAFDDEELKVALGLNSANSINISR 218 +S + +L E + DG AC +++ +E+ K + N N Sbjct: 99 TMSIERIQLMRA--YGTEVILTDGSLGMKACLEKLEELKKNEK-KYFVPNQFTNVNNPK- 154 Query: 219 LLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDT 278 E + L + + + G+F L K LP + + Sbjct: 155 -AHYETTAEEILKDLNNKVDVFICGTGTGGSFSGTAKKLKEK---LPNIKTFPVEPASSP 210 Query: 279 VPRFLHDGQWSPKATQATLSNAMDV-SQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQ 337 + L G P Q M + P + L + DD+ + Sbjct: 211 L---LSKGYIGPHKIQGM---GMSIGGIPAVYD----------GSLADDILVCEDDDAFE 254 Query: 338 QTMRELKELGYTSEPHAAVAYRAL----RDQLNPGEYGLFLGTAHPAKF 382 + G ++A ++ + G + L T K+ Sbjct: 255 MMRELSFKEGILGGISTGATFKAALDYSKENADKGLKIVVLSTDSGEKY 303 >5J5V-A nrPDB Length = 323 Score = 31.7 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 46/268 (17%), Positives = 80/268 (29%), Gaps = 27/268 (10%) Query: 102 PTLAFKDFGGRFMAQMLTHIAGDK----PVTILTATSGDTGAAVAHAFYGLPNVKVVILY 157 P+ + K R A M+ V ++ TSG+TG A+A+ K+ + Sbjct: 37 PSFSVK---CRIGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAAR-GYKLTLTM 92 Query: 158 PRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINIS 217 P +S + KL LG N+ ++ K L +N N Sbjct: 93 PE-TMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPE 151 Query: 218 RLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVND 277 + + E + + AG+ V R+I T Sbjct: 152 --IHEKTTGPEIWEDTDGQVDVFI-------------AGVGTGGTLTGVSRYIKGTKGKT 196 Query: 278 TVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGY--AAVDDET 335 + + SP QA + P+ + F LK + ++E Sbjct: 197 DLISVAVEPTDSPVIAQALAGEEIKPG-PHKIQGIGAGFIPANLDLKLVDKVIGITNEEA 255 Query: 336 TQQTMRELKELGYTSEPHAAVAYRALRD 363 R ++E G + + A A Sbjct: 256 ISTARRLMEEEGILAGISSGAAVAAALK 283 >3V75-A nrPDB Length = 301 Score = 29.8 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 31/91 (34%), Gaps = 11/91 (12%) Query: 106 FKDFGGRFMAQM---LTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKI 162 F+ FG R +A + + + ++ A GD G+ +A + + Sbjct: 89 FERFGSRGVAVLEKTVAEARAAGALVVMDAKRGDIGSTMAAYAEAFLRKDSPLFSDALTV 148 Query: 163 SPLQE--------KLFCTLGGNIETVAIDGD 185 SP +L G + +A+ + Sbjct: 149 SPYLGYGSLRPAVELARESGAGLFVLALTSN 179 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.122 0.290 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,124,123 Number of Sequences: 36641 Number of extensions: 469115 Number of successful extensions: 1645 Number of sequences better than 10.0: 36 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1541 Number of HSP's gapped (non-prelim): 61 length of query: 428 length of database: 10,336,785 effective HSP length: 100 effective length of query: 328 effective length of database: 6,672,685 effective search space: 2188640680 effective search space used: 2188640680 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 60 (27.9 bits)