BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00918 (260 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4QK3-A nrPDB 505 e-144 4CNR-A nrPDB 441 e-124 3D0N-A nrPDB 328 2e-90 1FLJ-A nrPDB 327 2e-90 1Z93-A nrPDB 324 2e-89 6FAF-A nrPDB 322 1e-88 6G4T-A nrPDB 315 1e-86 1URT-A nrPDB 271 2e-73 2W2J-A nrPDB 198 2e-51 1RJ5-A nrPDB 160 5e-40 4LU3-A nrPDB 159 1e-39 5LL9-A nrPDB 154 5e-38 5DVX-A nrPDB 153 6e-38 3FE4-A nrPDB 152 1e-37 4COQ-A nrPDB 142 2e-34 4X5S-A nrPDB 141 2e-34 6B9J-X nrPDB 131 3e-31 4ETQ-X nrPDB 131 3e-31 3ZNC-A nrPDB 128 2e-30 5JN8-A nrPDB 126 1e-29 4G7A-A nrPDB 121 2e-28 6EKI-A nrPDB 120 8e-28 4XIW-A nrPDB 110 8e-25 5HPJ-A nrPDB 107 8e-24 4XZ5-A nrPDB 106 9e-24 1KOQ-A nrPDB 103 7e-23 4TWL-A nrPDB 90 1e-18 5TT3-A nrPDB 81 5e-16 1Y7W-A nrPDB 79 2e-15 3Q31-A nrPDB 75 3e-14 3B1B-A nrPDB 66 2e-11 5Y29-A nrPDB 28 4.3 2GW3-A nrPDB 28 5.0 5WLC-ST nrPDB 28 5.6 1BII-A nrPDB 27 8.4 5E25-A nrPDB 27 8.5 2W3Z-A nrPDB 27 9.0 1S7T-A nrPDB 27 9.3 >4QK3-A nrPDB Length = 249 Score = 505 bits (1300), Expect = e-144, Method: Compositional matrix adjust. Identities = 249/260 (95%), Positives = 249/260 (95%), Gaps = 11/260 (4%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL Sbjct: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL Sbjct: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP Sbjct: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRK LM Sbjct: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRK-----------LM 229 Query: 241 VDNWRPAQPLKNRQIKASFK 260 VDNWRPAQPLKNRQIKASFK Sbjct: 230 VDNWRPAQPLKNRQIKASFK 249 >4CNR-A nrPDB Length = 262 Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust. Identities = 206/257 (80%), Positives = 226/257 (87%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 MSHHWGY KHNGPEHWHKDFPIA GERQSPVDIDT DP+LKPL++ Y +ATS R++ Sbjct: 3 MSHHWGYDKHNGPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRRMV 62 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 N+GH+FNVE+DDSQDKAVLK GPL GTYRL+QFHFHWGS D QGSEHTVD+KKYAAELHL Sbjct: 63 NDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL 122 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 VHWNTKYGDFG A Q+PDGLAV+G+FLKVG A P LQKV+D LDSIKTKGKS DF NFDP Sbjct: 123 VHWNTKYGDFGTAAQEPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP 182 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 LLP LDYWTYPGSLTTPPLLE VTWIVLKEPISVSS+Q+LKFR LNFN EGEPEELM Sbjct: 183 GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPEELM 242 Query: 241 VDNWRPAQPLKNRQIKA 257 + NWRPAQPLKNRQ++ Sbjct: 243 LANWRPAQPLKNRQVRG 259 >3D0N-A nrPDB Length = 264 Score = 328 bits (840), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 155/256 (60%), Positives = 192/256 (75%), Gaps = 1/256 (0%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGH 64 WGY +HNGP HW + FPIA G++QSP++I T KYD SL+PLS+ YD +++ I N+GH Sbjct: 8 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 67 Query: 65 AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN 124 +FNV+FDD+++K+VL+GGPL G+YRL Q H HWGS D GSEH VD YAAELH+VHWN Sbjct: 68 SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 127 Query: 125 T-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGL 183 + KY F +A +PDGLAVLG+FL++G LQK+ D LDSIK KGK FTNFD L Sbjct: 128 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 187 Query: 184 LPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDN 243 LP S DYWTYPGSLT PPLLE VTWIVLK+PI++SS+Q+ KFR L EGE +V N Sbjct: 188 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 247 Query: 244 WRPAQPLKNRQIKASF 259 RP QPLK R+++ASF Sbjct: 248 HRPPQPLKGRKVRASF 263 >1FLJ-A nrPDB Length = 260 Score = 327 bits (839), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 152/256 (59%), Positives = 189/256 (73%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGH 64 WGY HNGPEHWH+ +PIAKG+ QSP+++ T ++DPSL+P SVSYD ++ ILNNG Sbjct: 5 WGYASHNGPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKTILNNGK 64 Query: 65 AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN 124 V FDD+ D+++L+GGPL G YRL QFH HWGS D GSEHTVD KYAAELHLVHWN Sbjct: 65 TCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN 124 Query: 125 TKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLL 184 KY FG+A++QPDG+AV+GIFLK+G K Q ++D LD IKTKGK A F +FDP L Sbjct: 125 PKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPSCLF 184 Query: 185 PESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNW 244 P DYWTY GS TTPP EC+ W++LKEP++VSS+Q+ K R L + E EP +V NW Sbjct: 185 PACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLVGNW 244 Query: 245 RPAQPLKNRQIKASFK 260 RP QP+K R ++ASFK Sbjct: 245 RPPQPIKGRVVRASFK 260 >1Z93-A nrPDB Length = 266 Score = 324 bits (831), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 152/260 (58%), Positives = 187/260 (71%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 M+ WGY HNGP+HWH+ FP AKGE QSP+++ T ++DPSL+P SVSYD ++ IL Sbjct: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 NNG V FDD+ D+++L+GGPL G YRL QFH HWGS D GSEHTVD KYAAELHL Sbjct: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 VHWN KY F +A++Q DG+AV+GIFLK+G Q +D LD IKTKGK A FT FDP Sbjct: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 L P S DYWTY GS TTPP EC+ W++LKEP++VSS+Q+ K R L + E EP + Sbjct: 181 SSLFPASRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 Query: 241 VDNWRPAQPLKNRQIKASFK 260 V NWRP QP+ NR ++ASFK Sbjct: 241 VSNWRPPQPINNRVVRASFK 260 >6FAF-A nrPDB Length = 261 Score = 322 bits (824), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 155/256 (60%), Positives = 187/256 (73%), Gaps = 1/256 (0%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGH 64 WGY NGPE W K +PIA G QSPVDI T K+D SLKP+SVSY+ AT+ I+N GH Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH 65 Query: 65 AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN 124 +F+V F+D+ +++VLKGGP +YRL QFHFHWGS + GSEHTVD KY+AELH+ HWN Sbjct: 66 SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWN 125 Query: 125 T-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGL 183 + KY +A + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP L Sbjct: 126 SAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTL 185 Query: 184 LPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDN 243 LP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L N EG+ M N Sbjct: 186 LPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHN 245 Query: 244 WRPAQPLKNRQIKASF 259 RP QPLK R ++ASF Sbjct: 246 NRPTQPLKGRTVRASF 261 >6G4T-A nrPDB Length = 274 Score = 315 bits (807), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 147/259 (56%), Positives = 186/259 (71%), Gaps = 1/259 (0%) Query: 3 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNN 62 H WGYG+ +GP HWHK +PIA+G+RQSP++I + A Y PSL+PL +SY+ SL I NN Sbjct: 7 HGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNN 66 Query: 63 GHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVH 122 GH+ V+F+DS D+ V+ GGPL+G YRL QFHFHWG GSEHTVD K + +ELHLVH Sbjct: 67 GHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 126 Query: 123 WNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPR 181 WN KY FG+A PDGLAV+G+FL+ G P + ++ D L ++ KG A F+ F+P+ Sbjct: 127 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPK 186 Query: 182 GLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMV 241 LLP S YWTYPGSLTTPPL E VTWIVL+EPIS+S Q+ KFR L F E + MV Sbjct: 187 SLLPASRHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDERIHMV 246 Query: 242 DNWRPAQPLKNRQIKASFK 260 +N+RP QPLK R +KASF+ Sbjct: 247 NNFRPPQPLKGRVVKASFR 265 >1URT-A nrPDB Length = 248 Score = 271 bits (693), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 131/239 (54%), Positives = 167/239 (69%), Gaps = 1/239 (0%) Query: 23 AKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGG 82 A+G RQSP++I + YDP L PL VSYD A+ + N GHAF VEFDDS + + + GG Sbjct: 2 AEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISGG 61 Query: 83 PLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAVQQPDGLA 141 PL YRL QFHFHWG+ D GSEH VD Y AELHLVHWN TKY ++ KA +GLA Sbjct: 62 PLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLA 121 Query: 142 VLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPP 201 V+G+FLK+G+ LQK+VDVL ++ K +FDP L+P DYWTYPGSLTTPP Sbjct: 122 VIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRDYWTYPGSLTTPP 181 Query: 202 LLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 260 L E VTWIV K P+ VS Q+ FR L F+G GE E++MV+N+RP QPL++R++++SF+ Sbjct: 182 LAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR 240 >2W2J-A nrPDB Length = 291 Score = 198 bits (503), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 105/257 (40%), Positives = 157/257 (61%), Gaps = 15/257 (5%) Query: 16 WHKDFPIAKGERQSPVDIDTHTAKYDPSL--KPLSVSYDQATSLRILNNGHAFNVEFDDS 73 W FP A GE QSP+++++ A+YDPSL LS +Y + N+GH V Sbjct: 38 WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVIL--- 94 Query: 74 QDKAVLKGGPLDG--TYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDF 130 + K+VL GGPL + L + FHWG + +GSEHTV+ K + ELHL+HWN T +G Sbjct: 95 KSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSI 154 Query: 131 GKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESL-- 188 +AV +P G+A++ +F+++G GL+ V ++L I+ KGKS F+P LLP+ L Sbjct: 155 DEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLR 214 Query: 189 DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP-----EELMVDN 243 DYW Y GSLT PP E VTWI+ + P+++S Q+ +FR+L + +G + ++ DN Sbjct: 215 DYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDN 274 Query: 244 WRPAQPLKNRQIKASFK 260 +RP QPL +R I+A+F+ Sbjct: 275 FRPTQPLSDRVIRAAFQ 291 >1RJ5-A nrPDB Length = 261 Score = 160 bits (405), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 95/264 (35%), Positives = 138/264 (52%), Gaps = 12/264 (4%) Query: 3 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSV-SYDQATS--LRI 59 HHW Y +G +HW +P G+ QSP++I T + +DP L + YDQ + L + Sbjct: 3 HHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPLDL 62 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDG-QGSEHTVDKKKYAAEL 118 NNGH + L G L Y Q H HWG +GSEH ++ + AAEL Sbjct: 63 HNNGHTVQLSL-----PPTLHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAEL 117 Query: 119 HLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAK-PGLQKVVDVLDSIKTKGKSADFT 176 H+VH++++ Y +A Q+P GLAVLGI ++VG + P ++ L I+ K + Sbjct: 118 HVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTSVP 177 Query: 177 NFDPRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGE 235 F R L P+ L+ ++ Y GSLTTPP + V W V +S Q+ K ++ + E + Sbjct: 178 PFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEED 237 Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259 P E +V N+R QPL R I ASF Sbjct: 238 PSEPLVQNYRVPQPLNQRTIFASF 261 >4LU3-A nrPDB Length = 279 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 96/263 (36%), Positives = 136/263 (51%), Gaps = 12/263 (4%) Query: 4 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSV-SYDQATS--LRIL 60 HW Y +G +HW +P QSP+DI T + +DP L L YDQ + L + Sbjct: 6 HWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLH 65 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQG-SEHTVDKKKYAAELH 119 NNGH + + L G L Y Q H HWG G SEH ++ + AELH Sbjct: 66 NNGHTVQLSL-----PSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELH 120 Query: 120 LVHWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKP-GLQKVVDVLDSIKTKGKSADFTN 177 +VH+++ Y +A ++P GLAVLGI ++VG K + ++ L ++ K + Sbjct: 121 IVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPP 180 Query: 178 FDPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP 236 F+ R LLP+ L Y+ Y GSLTTPP + V W V +S EQ+ K + F+ E EP Sbjct: 181 FNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEP 240 Query: 237 EELMVDNWRPAQPLKNRQIKASF 259 +L+V N+R QPL R + ASF Sbjct: 241 SKLLVQNYRALQPLNQRMVFASF 263 >5LL9-A nrPDB Length = 263 Score = 154 bits (388), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 94/264 (35%), Positives = 137/264 (51%), Gaps = 15/264 (5%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSLRIL--N 61 W Y +G W K +P G QSP+D+ + +YD SL PL Y+ + + + L N Sbjct: 4 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 63 Query: 62 NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSL-DGQGSEHTVDKKKYAAELHL 120 NGH+ + ++G L Y Q H HWG+ D GSEHTV + +AAELH+ Sbjct: 64 NGHSVKLNLPSDMH---IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 118 Query: 121 VHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 VH+N+ Y D A + +GLAVL + +++GS P K+ L +K KG+ A F+ Sbjct: 119 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 178 Query: 180 PRGLLPE-SLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGE--- 235 LLPE + +Y+ Y GSLTTPP V W V + P+ +S EQ+L + + Sbjct: 179 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 238 Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259 P E M++N+R Q R + SF Sbjct: 239 PRE-MINNFRQVQKFDERLVYTSF 261 >5DVX-A nrPDB Length = 260 Score = 153 bits (387), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 95/261 (36%), Positives = 137/261 (52%), Gaps = 15/261 (5%) Query: 4 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQAT---SLRIL 60 HW YG G W + P G QSPVDI A + P+L+PL +S Q LR+ Sbjct: 1 HWRYG---GDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLR 57 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 NNGH+ + + +K GP YR +Q H HWG+ GSEHTV+ ++ AE+H+ Sbjct: 58 NNGHSVQLTLPPGLE---MKLGP-GREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHV 113 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAK-PGLQKVVDVLDSIKTKGKSADFTNFD 179 VH +TKY +A+ +P GLAVL FL+ G + ++++ L+ I +G D Sbjct: 114 VHLSTKYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLD 173 Query: 180 PRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 LLP Y+ Y GSLTTPP + V W V + +S+S++Q+ L+ G + Sbjct: 174 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQL---HTLSDTLWGPGDS 230 Query: 239 LMVDNWRPAQPLKNRQIKASF 259 + N+R QPL R I+ASF Sbjct: 231 RLQLNFRATQPLNGRVIEASF 251 >3FE4-A nrPDB Length = 278 Score = 152 bits (384), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 89/252 (35%), Positives = 137/252 (54%), Gaps = 14/252 (5%) Query: 15 HWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YD-QATSLRILNNGHAFNVEFDD 72 HW + +P G+RQSP+++ +Y+PSLK L+++ Y+ QA ++NNGH + Sbjct: 15 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 74 Query: 73 SQDKAVLKGGPLDGTYRLIQFHFHWG--SLDGQGSEHTVDKKKYAAELHLVHWNTKYGDF 130 + V G Y Q HFHWG S + GSEHTVD ++ E+H+VH+N+KY + Sbjct: 75 TMRMTVADGT----VYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSY 130 Query: 131 GKAVQQPDGLAVLGIFLKVGS--AKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESL 188 A PDGLAVL F++V + + L +IK G+ T D + +LP +L Sbjct: 131 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 190 Query: 189 D-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPA 247 Y+TY GSLTTPP E V W VL + + +S QV K + + + +++R Sbjct: 191 QHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN---KTIHNDYRRT 247 Query: 248 QPLKNRQIKASF 259 QPL +R ++++F Sbjct: 248 QPLNHRVVESNF 259 >4COQ-A nrPDB Length = 247 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 101/257 (39%), Positives = 134/257 (52%), Gaps = 41/257 (15%) Query: 4 HWGYGKHNGPEHW---HKDFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HWGY GPEHW ++ + K G+ QSP+DI++ A L P+SV Y + + + Sbjct: 25 HWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADA-VKACLAPVSVYY-VSDAKYV 82 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 +NNGH V + V+ G + L QFHFH SEHTV+ K Y E H Sbjct: 83 VNNGHTIKVVMG-GRGYVVVDGK----RFYLKQFHFH------APSEHTVNGKHYPFEAH 131 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFT-NF 178 VH + K G+ + VLG+F KVG P L+KV V+ + G+ T Sbjct: 132 FVHLD-KNGN----------ITVLGVFFKVGKENPELEKVWRVMP--EEPGQKRHLTARI 178 Query: 179 DPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 DP LLPE+ DY+ Y GSLTTPP E V WIV KEP+ +S EQ+ KFRK+ Sbjct: 179 DPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKV---------- 228 Query: 239 LMVDNWRPAQPLKNRQI 255 + DN RP QPL R++ Sbjct: 229 MGFDNNRPVQPLNARKV 245 >4X5S-A nrPDB Length = 232 Score = 141 bits (356), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/260 (37%), Positives = 135/260 (51%), Gaps = 40/260 (15%) Query: 3 HHWGYGKHNGPEHWHK---DFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HHW Y NGPE+W K ++ + QSPVDI + K L+ L ++Y++A + I Sbjct: 8 HHWSYEGENGPENWAKLNPEYFWCNLKNQSPVDI-SDNYKVHAKLEKLHINYNKAVNPEI 66 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 +NNGH V + K +KG Y L QFHFH SEHTV+ K Y E+H Sbjct: 67 VNNGHTIQVNVLEDF-KLNIKGK----EYHLKQFHFH------APSEHTVNGKYYPLEMH 115 Query: 120 LVHWNTKYGDFGKAVQQPDG-LAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNF 178 LVH + DG +AV+G+F K G A P L KV +++K +G + Sbjct: 116 LVH------------KDKDGNIAVIGVFFKEGKANPELDKVFK--NALKEEGSKVFDGSI 161 Query: 179 DPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 + LLP +Y+TY GSLTTPP E V WIVLK+PI+ S +Q+ F+ + Sbjct: 162 NINALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSI---------- 211 Query: 239 LMVDNWRPAQPLKNRQIKAS 258 + +N RP QP+ +R I S Sbjct: 212 MKHNNNRPTQPINSRYILES 231 >6B9J-X nrPDB Length = 241 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 84/225 (37%), Positives = 122/225 (54%), Gaps = 12/225 (5%) Query: 26 ERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLD 85 ++ SP++I+T A + LKPL + Y+++ I N G + F + GG L Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKG----GYISGGFLP 58 Query: 86 GTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAVQQPDGLAVLG 144 Y L H +WG D GS H +D KY+ E++LVHWN KY + +A + DGL ++ Sbjct: 59 NEYVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 145 IFLKVGSAKPG-LQKVVDVLDSIKTKGKSADFTN-FDPRGLLPESLDYWTYPGSLTTPPL 202 IFL+V K QK+V+ LDSI++ SA F + F LLP LDY+TY G TT Sbjct: 119 IFLQVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINH 176 Query: 203 LECVTWIVLKEPISVSSEQVLKFRKL--NFNGEGEPEELMVDNWR 245 WI+ PI++ S+Q+ KFR L N EG+P + +N+R Sbjct: 177 SADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKP-HYITENYR 220 >4ETQ-X nrPDB Length = 269 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 84/225 (37%), Positives = 122/225 (54%), Gaps = 12/225 (5%) Query: 26 ERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLD 85 ++ SP++I+T A + LKPL + Y+++ I N G + F + GG L Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKG----GYISGGFLP 58 Query: 86 GTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAVQQPDGLAVLG 144 Y L H +WG D GS H +D KY+ E++LVHWN KY + +A + DGL ++ Sbjct: 59 NEYVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 145 IFLKVGSAKPG-LQKVVDVLDSIKTKGKSADFTN-FDPRGLLPESLDYWTYPGSLTTPPL 202 IFL+V K QK+V+ LDSI++ SA F + F LLP LDY+TY G TT Sbjct: 119 IFLQVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINH 176 Query: 203 LECVTWIVLKEPISVSSEQVLKFRKL--NFNGEGEPEELMVDNWR 245 WI+ PI++ S+Q+ KFR L N EG+P + +N+R Sbjct: 177 SADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKP-HYITENYR 220 >3ZNC-A nrPDB Length = 258 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 86/249 (34%), Positives = 118/249 (47%), Gaps = 16/249 (6%) Query: 12 GPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKP-LSVSYDQATSLRILNNGHAFNVEF 70 GPE W K +QSP++I T K +P L P + V YDQ I NN H + Sbjct: 16 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTL 72 Query: 71 DDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDF 130 A + GG L Y +Q H HW + + GSEH++D + +A E+H+VH Sbjct: 73 GGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLT---- 125 Query: 131 GKAVQQPDGLAVLGIFLKVG-SAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLD 189 D AVL ++VG G Q +V+ L SI ++ + +LP S Sbjct: 126 SSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTK 185 Query: 190 ---YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRP 246 Y+ Y GSLTTP E V W V K+PI + Q L+F K N + + + M DN RP Sbjct: 186 MYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSK-NLYYDEDQKLNMKDNVRP 244 Query: 247 AQPLKNRQI 255 QPL RQ+ Sbjct: 245 LQPLGKRQV 253 >5JN8-A nrPDB Length = 266 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 91/268 (33%), Positives = 130/268 (48%), Gaps = 18/268 (6%) Query: 4 HWGYGKHNGPEHWHKDFPI-----AKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSL 57 HW Y ++ P+ + +RQSP++I T AK D L S YD+ + Sbjct: 4 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 63 Query: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 + NNGH+ + ++ KA + GG L Y+ Q H HW L +GSEH++D + +A E Sbjct: 64 TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 120 Query: 118 LHLVHWNTKYGDFG-KAVQQP-DGLAVLGIFLKVGS-AKPGLQKVVDVLDSIKTKGKSAD 174 +H+VH K K Q P D +AVL ++ G+ G Q +V+ L +I S Sbjct: 121 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 180 Query: 175 FTNFDPRGLLPES---LDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKF-RKLNF 230 LLP+ Y+ Y GSLTTP E V W V +EPI + EQ+L F +KL + Sbjct: 181 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 240 Query: 231 NGEGEPEELMVDNWRPAQPLKNRQIKAS 258 + E M DN RP Q L R + S Sbjct: 241 DKEQTVS--MKDNVRPLQQLGQRTVIKS 266 >4G7A-A nrPDB Length = 248 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 88/263 (33%), Positives = 130/263 (49%), Gaps = 40/263 (15%) Query: 1 MSHHWGYGKHNGPEHWHK---DFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSL 57 + H W Y GPEHW + +F K + QSP++ID K +L L++ Y A Sbjct: 22 LEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINIDK-KYKVKANLPKLNLYYKTAKES 80 Query: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 ++NNGH ++ + +D + L Y+L QFHFH SEHT++KK Y E Sbjct: 81 EVVNNGHT--IQINIKEDNTL---NYLGEKYQLKQFHFH------TPSEHTIEKKSYPLE 129 Query: 118 LHLVHWNTKYGDFGKAVQQPDG-LAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFT 176 +H VH + DG + V+G+ K+G L K+++V + +G+ Sbjct: 130 IHFVH------------KTEDGKILVVGVMAKLGKTNKELDKILNVAPA--EEGEKILDK 175 Query: 177 NFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP 236 N + L+P+ Y TY GSLTTPP E V WIVLK+PIS+S +Q+ K + + N Sbjct: 176 NLNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVN----- 230 Query: 237 EELMVDNWRPAQPLKNRQIKASF 259 N RP Q + +R I F Sbjct: 231 -----PNNRPVQEINSRWIIEGF 248 >6EKI-A nrPDB Length = 226 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 89/258 (34%), Positives = 123/258 (47%), Gaps = 46/258 (17%) Query: 4 HWGYGKHNGPEHW---HKDFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HW Y GP+HW ++ + K G+ QSPVDI + + L+ + ++Y S I Sbjct: 5 HWSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDI---SRIVEAELEKIKINYSSGGS-SI 60 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGT-YRLIQFHFHWGSLDGQGSEHTVDKKKYAAEL 118 NNGH V ++ V DG + L QFHFH SEHT+ K Y E Sbjct: 61 TNNGHTIKVSYEPGSYIIV------DGIRFELKQFHFH------APSEHTIKGKSYPFEA 108 Query: 119 HLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVL-DSIKTKGKSADFTN 177 H VH + LAV+G+ K G P ++K+ + L ++ KT + Sbjct: 109 HFVH-----------ADKDGNLAVIGVIFKEGKKNPIIEKIWENLPEAGKTIKLAHKINA 157 Query: 178 FDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPE 237 +D LLP+ Y+ Y GSLTTPP E V WIV++E + +S EQ+ KFRKL Sbjct: 158 YD---LLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKL--------- 205 Query: 238 ELMVDNWRPAQPLKNRQI 255 + D RP QPL R I Sbjct: 206 -MGGDTNRPVQPLNARMI 222 >4XIW-A nrPDB Length = 239 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 88/262 (33%), Positives = 120/262 (45%), Gaps = 39/262 (14%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDI--DTHTAKYDPSLKPLSVSYDQATSLRILNN 62 W YG+ GP W A G+RQSP++I +T K D + +Y +LN Sbjct: 4 WNYGEVAGPPTWKGV--CATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFEKCDVLNT 61 Query: 63 GHA-FNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121 GH V F + + A + L+ L+QFHFH SEH +D ++YA E HLV Sbjct: 62 GHGTMQVNFP-AGNLAFIGNMELE----LLQFHFH------APSEHAMDGRRYAMEAHLV 110 Query: 122 HWNTKYGDFGKAVQQPDGLAVLGIFLKVGS--AKPGLQKVVDVLDSIKTKGKSADFTNFD 179 H N G+ LAVLGI L+ G P L ++V + K + + Sbjct: 111 HKNKSTGN----------LAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSP-KGIN 159 Query: 180 PRGLLPESLDYWT-----YPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEG 234 P LLP+ T YPGSLTTPP E V W V +PI V Q+L F + F G+ Sbjct: 160 PVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDF--MRFVGD- 216 Query: 235 EPEELMVDNWRPAQPLKNRQIK 256 + N RP Q L +R ++ Sbjct: 217 --NKTYATNTRPLQLLNSRLVE 236 >5HPJ-A nrPDB Length = 217 Score = 107 bits (266), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 116/255 (45%), Gaps = 45/255 (17%) Query: 5 WGYGKHNGPEHWHKDFP-IAKGERQSPVDIDTHTAKYDPSLKPLSVSYD-QATSLRILNN 62 W Y +G EHW F A+G Q+P+DI+ T L PL + Y+ Q T L +NN Sbjct: 2 WSYTGEHGTEHWGDSFATCAEGVNQTPIDINQTT---QAELAPLHLDYEGQVTEL--VNN 56 Query: 63 GHAFNVEFDDSQDKAVLKGGPLDG-TYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121 GH V DG T+ L QFHFH SE+ + K+Y E H V Sbjct: 57 GHTIQANLTGKNTLTV------DGKTFELKQFHFH------TPSENYLKGKQYPLEAHFV 104 Query: 122 HWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTN-FDP 180 H K G+ LAV+ + G ++ +L SI +KG++ + +P Sbjct: 105 HATDK-GE----------LAVVAVMFDFGPRSNN--ELTTLLASIPSKGQTVELKEALNP 151 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 LLP +Y+ + GSLTTPP E V W V++EP + S Q K + +M Sbjct: 152 ADLLPRDREYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQA-----------VM 200 Query: 241 VDNWRPAQPLKNRQI 255 +N RP QPL R I Sbjct: 201 GNNARPLQPLNARLI 215 >4XZ5-A nrPDB Length = 233 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 83/260 (31%), Positives = 116/260 (44%), Gaps = 40/260 (15%) Query: 4 HWGYGKHNGPEHWHK---DFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HWGY GP++W + +F K G+ QSP+++ TA SL V Y + T+L++ Sbjct: 3 HWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRE-TALKL 61 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDG-TYRLIQFHFHWGSLDGQGSEHTVDKKKYAAEL 118 +NNGH V + +K ++G Y L+Q+HFH SEH D Y E+ Sbjct: 62 INNGHTLQVNIPLG---SYIK---INGHRYELLQYHFH------TPSEHQRDGFNYPMEM 109 Query: 119 HLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNF 178 HLVH K GD LAV+ I + G L K++ L K + + Sbjct: 110 HLVH---KDGD--------GNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKI 158 Query: 179 DPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 P P ++ Y GSLTTPP E V W+V K+PI S Q+ K E Sbjct: 159 HPAKFFPADKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMH-----------E 207 Query: 239 LMVDNWRPAQPLKNRQIKAS 258 + N RP Q R + S Sbjct: 208 YLGSNARPVQRQNARTLLKS 227 >1KOQ-A nrPDB Length = 223 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 118/256 (46%), Gaps = 41/256 (16%) Query: 4 HWGYGKHNGPEHW---HKDFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HWGY H+ PE W ++F + G+ QSPV+I + P++K V+Y + + + + Sbjct: 3 HWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITETVSGKLPAIK---VNY-KPSMVDV 58 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 NNGH V + + + + G TY L QFHFH SE+ + + + E H Sbjct: 59 ENNGHTIQVNYPEGGNTLTVNGR----TYTLKQFHFH------VPSENQIKGRTFPMEAH 108 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 VH + +QP VL + + G L + +V+ T GK FD Sbjct: 109 FVHLDEN--------KQP---LVLAVLYEAGKTNGRLSSIWNVMP--MTAGKVKLNQPFD 155 Query: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEEL 239 LLP+ L Y+ + GSLTTPP E V+W+VLK + Q KF + + Sbjct: 156 ASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTR----------AV 205 Query: 240 MVDNWRPAQPLKNRQI 255 +N RP QPL R + Sbjct: 206 GSENNRPVQPLNARVV 221 >4TWL-A nrPDB Length = 246 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 70/253 (27%), Positives = 110/253 (43%), Gaps = 34/253 (13%) Query: 8 GKHNGPEHWHKDFP----IAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNG 63 G NGPE+W P KG QSP+ + + +D +L L +Y +A R+ N+G Sbjct: 10 GNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNY-RAVDARLRNSG 68 Query: 64 HAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHW 123 H V+F + + Y+L + HFH SEH ++ +++ E LVH Sbjct: 69 HDVLVDFKGNAGSLSIN----RVEYQLKRIHFH------SPSEHEMNGERFDLEAQLVHE 118 Query: 124 NTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSA-DFTNFDPRG 182 + Q AV+ I + G A P L + D + K+ + DP Sbjct: 119 S-----------QDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEINAGVVDPNQ 167 Query: 183 LLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVD 242 L + Y+ Y GS T PP E ++W V+++ +VS QVL ++ E ++ Sbjct: 168 LQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQ-------AVNENAIN 220 Query: 243 NWRPAQPLKNRQI 255 N RP QP R + Sbjct: 221 NARPLQPTNFRSV 233 >5TT3-A nrPDB Length = 234 Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 73/259 (28%), Positives = 109/259 (42%), Gaps = 44/259 (16%) Query: 5 WGY-GKHNGPEHW---HKDFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 W Y K NGP W HKDF + K G+ QSP++I+ + D + L Y + + Sbjct: 10 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKA--DLQFKYAASKPKAV 67 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 H F+ + + +G Y L HFH E ++ K H Sbjct: 68 FFTHHTLKASFEPT-NHINYRGH----DYVLDNVHFH------APMEFLINNKTRPLSAH 116 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 VH + K G+ L VL I + G P L +++ + K +F Sbjct: 117 FVHKDAK----GR-------LLVLAIGFEEGKENPNLDPILEGIQ------KKQNFKEVA 159 Query: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEEL 239 LP+S++Y+ + GSLT PP E V W V++EP+ VS++Q+ + +K N Sbjct: 160 LDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSP------ 213 Query: 240 MVDNWRPAQPLKNRQIKAS 258 N RP QP N I S Sbjct: 214 ---NQRPVQPDYNTVIIKS 229 >1Y7W-A nrPDB Length = 291 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 78/258 (30%), Positives = 109/258 (42%), Gaps = 36/258 (13%) Query: 20 FPIAKGERQSPVDIDTH--------TAKYDPSLKPLSVSYDQATSLRILNNG----HAFN 67 +P G QSP+DI+T+ + SL L+V QA + + N Sbjct: 43 YPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLTNAKVDLEQGMK 102 Query: 68 VEFDD-SQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK 126 V FD + + ++ G ++ IQFHFH SEHT++ Y ELH+V Sbjct: 103 VTFDQPAANLPTIEIGGTTKSFVPIQFHFHHFL-----SEHTINGIHYPLELHIVMQEQD 157 Query: 127 YGDFGKAVQQPDGLAVLGIFLK--------VGSAKPGLQ-KVVDVLDSIKTKGKSADFTN 177 D A LAV+GI K + S + ++ K+ D S G S D N Sbjct: 158 PADVATAQ-----LAVIGIMYKYSENGDAFLNSLQTQIEGKIGDGTASYGDTGVSIDNIN 212 Query: 178 FDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPE 237 + LLP SL Y Y GSLTTP E V W V P V+ EQ+ F + + Sbjct: 213 VKTQ-LLPSSLKYAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKLFVDVTMGAHAGAD 271 Query: 238 ELMVDNWRPAQPLKNRQI 255 V N R Q L +R++ Sbjct: 272 ---VVNNRMIQDLGDREV 286 >3Q31-A nrPDB Length = 244 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 73/252 (28%), Positives = 107/252 (42%), Gaps = 34/252 (13%) Query: 2 SHHWGYGKHNGPEHWH----KDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSL 57 ++ + Y GP +W+ + AKG+ QSP+ ID+ Y S L + A Sbjct: 8 ANKFNYTGLGGPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAAS-GSLKLDLPLADGS 66 Query: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 ++ N G V + A K TY L QFHFH SEH V+++ + E Sbjct: 67 KLENLGFGLQVTLTNGSLTANSK------TYTLAQFHFH------TPSEHHVNEEHFPME 114 Query: 118 LHLVHWNTKYGDFGKAVQQPDGLAVLGIFLK---VGSAKPGLQKVVDVLDSIKTKGKSAD 174 +H V F A ++ AV+G F + VG + P V +D+I G S Sbjct: 115 VHFV--------FQTAAKET---AVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGTSTT 163 Query: 175 FTNFDPRGLLP--ESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRK-LNFN 231 D GLL + Y GSLTTPP E V W + EP+ ++ + K +K + +N Sbjct: 164 TGQLDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKIIKYN 223 Query: 232 GEGEPEELMVDN 243 L DN Sbjct: 224 ARYTQNALGQDN 235 >3B1B-A nrPDB Length = 377 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 76/267 (28%), Positives = 117/267 (43%), Gaps = 61/267 (22%) Query: 4 HWGYGKHNGPEHWH-KD-----FPIAKGERQSPVDI------DTHTAKYDPSLKPLSVSY 51 HW +G NG E+W KD + G +QSP+++ D +K L+ SY Sbjct: 39 HWDHGL-NG-ENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQ-TQWSY 95 Query: 52 ----DQATSLRILNNGHAFNVEF-----------------DDSQDKAVLKGGPLDGTYRL 90 TS++++NNGH V++ ++ VL+ P D R+ Sbjct: 96 PDLMSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAADRV 155 Query: 91 I----QFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIF 146 QFHFH SEH + K Y ELH+VH T+ + K +V GI Sbjct: 156 TAVPTQFHFH------STSEHLLAGKIYPLELHIVHQVTEKLEACKG----GCFSVTGIL 205 Query: 147 LKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRG-------LLPESLDYWTYPGSLTT 199 ++ + P + + + ++ ++ F+N P G LLP DY TY GSLTT Sbjct: 206 FQLDNG-PDNELLEPIFANMPSR--EGTFSNL-PAGTTIKLGELLPSDRDYVTYEGSLTT 261 Query: 200 PPLLECVTWIVLKEPISVSSEQVLKFR 226 PP E + W V+ +P +S Q ++R Sbjct: 262 PPCSEGLLWHVMTQPQRISFGQWNRYR 288 >5Y29-A nrPDB Length = 377 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 3/76 (3%) Query: 69 EFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV--HWNTK 126 + D S ++ G + G L+ H W D + E V+ K+Y ++ L WN Sbjct: 30 DIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDS 89 Query: 127 YGD-FGKAVQQPDGLA 141 GD + K V P A Sbjct: 90 AGDKYSKLVNDPAARA 105 >2GW3-A nrPDB Length = 227 Score = 27.7 bits (60), Expect = 5.0, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 9/47 (19%) Query: 62 NGHAFNVEFD---------DSQDKAVLKGGPLDGTYRLIQFHFHWGS 99 NGH F +E D S D V +G PL Y ++ FH+G+ Sbjct: 21 NGHQFVIEGDGKGHPFEGKQSMDLVVKEGAPLPFAYDILTTAFHYGN 67 >5WLC-ST nrPDB Length = 792 Score = 27.7 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 26 ERQSPVDIDTHTAKYDPSLKPLSVSYD 52 + PV I TH KY+ + P SYD Sbjct: 685 QNHKPVSIPTHAPKYEENFNPDKKSYD 711 >1BII-A nrPDB Length = 365 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 9 KHNGPEHWHKDFPIAKGERQS-PVDIDTHTAKYDPS 43 + GPE+W ++ AKG QS VD+ T Y+ S Sbjct: 77 EQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQS 112 >5E25-A nrPDB Length = 291 Score = 26.9 bits (58), Expect = 8.5, Method: Compositional matrix adjust. Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 15/118 (12%) Query: 123 WNTKYGDFGKAVQQPDGLAVLGIFLK---VGSAKPGLQKVV---DVLDSIKTKGKSADFT 176 W YGD GL + + ++ + S P ++ + ++L I+ K D Sbjct: 119 WGKLYGDL-----YEKGLKAITVAIRRNAIDSLPPNIKSLNYLNNILAKIEANAKGGDEA 173 Query: 177 NF-DPRGLLPESLD---YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNF 230 F D G + E + G++TTPP L + I + I + +E + FR+ N Sbjct: 174 IFLDHNGYISEGSGDNIFIVKNGTITTPPTLNNLKGITRQVVIELINELEIPFREANI 231 >2W3Z-A nrPDB Length = 311 Score = 26.9 bits (58), Expect = 9.0, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 11/79 (13%) Query: 86 GTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGI 145 G +R H W L+ DK+ A + + WN GD +P +A + Sbjct: 208 GVWRYPGGHLSWTGLEA------ADKQLAAQGIQWMDWNAAVGDAEPLATRPTTVASMLA 261 Query: 146 FLKVGSAK----PGLQKVV 160 FL GSAK P +Q V+ Sbjct: 262 FLD-GSAKIATNPNVQVVL 279 >1S7T-A nrPDB Length = 348 Score = 26.9 bits (58), Expect = 9.3, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 9 KHNGPEHWHKDFPIAKGERQS-PVDIDTHTAKYDPS 43 + GPE+W ++ AKG QS VD+ T Y+ S Sbjct: 53 EQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQS 88 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4QK3-A nrPDB 393 e-110 4CNR-A nrPDB 389 e-109 1FLJ-A nrPDB 378 e-105 1Z93-A nrPDB 377 e-105 6G4T-A nrPDB 371 e-103 3D0N-A nrPDB 357 3e-99 6FAF-A nrPDB 355 1e-98 1URT-A nrPDB 328 1e-90 2W2J-A nrPDB 298 2e-81 4LU3-A nrPDB 295 1e-80 1RJ5-A nrPDB 295 2e-80 5LL9-A nrPDB 280 4e-76 5DVX-A nrPDB 280 4e-76 5JN8-A nrPDB 274 3e-74 4COQ-A nrPDB 273 5e-74 3FE4-A nrPDB 272 1e-73 3ZNC-A nrPDB 268 2e-72 4X5S-A nrPDB 267 4e-72 4G7A-A nrPDB 257 4e-69 6EKI-A nrPDB 256 1e-68 4XZ5-A nrPDB 243 8e-65 5HPJ-A nrPDB 241 3e-64 1KOQ-A nrPDB 235 1e-62 4XIW-A nrPDB 233 5e-62 4ETQ-X nrPDB 225 2e-59 4TWL-A nrPDB 222 9e-59 6B9J-X nrPDB 222 1e-58 1Y7W-A nrPDB 209 1e-54 5TT3-A nrPDB 207 4e-54 3Q31-A nrPDB 202 1e-52 3B1B-A nrPDB 184 3e-47 Sequences not found previously or not previously below threshold: 1S7T-A nrPDB 34 0.080 5OQL-U nrPDB 33 0.11 5J6H-A nrPDB 32 0.21 1BII-A nrPDB 32 0.40 5OQI-A nrPDB 30 1.4 5KST-A nrPDB 30 1.4 5TTH-B nrPDB 30 1.5 4OKD-A nrPDB 29 2.5 3V65-B nrPDB 28 3.5 3V64-C nrPDB 28 4.5 CONVERGED! >4QK3-A nrPDB Length = 249 Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats. Identities = 249/260 (95%), Positives = 249/260 (95%), Gaps = 11/260 (4%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL Sbjct: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL Sbjct: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP Sbjct: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL M Sbjct: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL-----------M 229 Query: 241 VDNWRPAQPLKNRQIKASFK 260 VDNWRPAQPLKNRQIKASFK Sbjct: 230 VDNWRPAQPLKNRQIKASFK 249 >4CNR-A nrPDB Length = 262 Score = 389 bits (1000), Expect = e-109, Method: Composition-based stats. Identities = 206/256 (80%), Positives = 226/256 (88%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 MSHHWGY KHNGPEHWHKDFPIA GERQSPVDIDT DP+LKPL++ Y +ATS R++ Sbjct: 3 MSHHWGYDKHNGPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRRMV 62 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 N+GH+FNVE+DDSQDKAVLK GPL GTYRL+QFHFHWGS D QGSEHTVD+KKYAAELHL Sbjct: 63 NDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL 122 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 VHWNTKYGDFG A Q+PDGLAV+G+FLKVG A P LQKV+D LDSIKTKGKS DF NFDP Sbjct: 123 VHWNTKYGDFGTAAQEPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP 182 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 LLP LDYWTYPGSLTTPPLLE VTWIVLKEPISVSS+Q+LKFR LNFN EGEPEELM Sbjct: 183 GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPEELM 242 Query: 241 VDNWRPAQPLKNRQIK 256 + NWRPAQPLKNRQ++ Sbjct: 243 LANWRPAQPLKNRQVR 258 >1FLJ-A nrPDB Length = 260 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 152/259 (58%), Positives = 190/259 (73%) Query: 2 SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILN 61 + WGY HNGPEHWH+ +PIAKG+ QSP+++ T ++DPSL+P SVSYD ++ ILN Sbjct: 2 AKEWGYASHNGPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKTILN 61 Query: 62 NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121 NG V FDD+ D+++L+GGPL G YRL QFH HWGS D GSEHTVD KYAAELHLV Sbjct: 62 NGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV 121 Query: 122 HWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPR 181 HWN KY FG+A++QPDG+AV+GIFLK+G K Q ++D LD IKTKGK A F +FDP Sbjct: 122 HWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPS 181 Query: 182 GLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMV 241 L P DYWTY GS TTPP EC+ W++LKEP++VSS+Q+ K R L + E EP +V Sbjct: 182 CLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLV 241 Query: 242 DNWRPAQPLKNRQIKASFK 260 NWRP QP+K R ++ASFK Sbjct: 242 GNWRPPQPIKGRVVRASFK 260 >1Z93-A nrPDB Length = 266 Score = 377 bits (969), Expect = e-105, Method: Composition-based stats. Identities = 152/260 (58%), Positives = 187/260 (71%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 M+ WGY HNGP+HWH+ FP AKGE QSP+++ T ++DPSL+P SVSYD ++ IL Sbjct: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 NNG V FDD+ D+++L+GGPL G YRL QFH HWGS D GSEHTVD KYAAELHL Sbjct: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 VHWN KY F +A++Q DG+AV+GIFLK+G Q +D LD IKTKGK A FT FDP Sbjct: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 Query: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240 L P S DYWTY GS TTPP EC+ W++LKEP++VSS+Q+ K R L + E EP + Sbjct: 181 SSLFPASRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 Query: 241 VDNWRPAQPLKNRQIKASFK 260 V NWRP QP+ NR ++ASFK Sbjct: 241 VSNWRPPQPINNRVVRASFK 260 >6G4T-A nrPDB Length = 274 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 147/259 (56%), Positives = 186/259 (71%), Gaps = 1/259 (0%) Query: 3 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNN 62 H WGYG+ +GP HWHK +PIA+G+RQSP++I + A Y PSL+PL +SY+ SL I NN Sbjct: 7 HGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNN 66 Query: 63 GHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVH 122 GH+ V+F+DS D+ V+ GGPL+G YRL QFHFHWG GSEHTVD K + +ELHLVH Sbjct: 67 GHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 126 Query: 123 WN-TKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPR 181 WN KY FG+A PDGLAV+G+FL+ G P + ++ D L ++ KG A F+ F+P+ Sbjct: 127 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPK 186 Query: 182 GLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMV 241 LLP S YWTYPGSLTTPPL E VTWIVL+EPIS+S Q+ KFR L F E + MV Sbjct: 187 SLLPASRHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDERIHMV 246 Query: 242 DNWRPAQPLKNRQIKASFK 260 +N+RP QPLK R +KASF+ Sbjct: 247 NNFRPPQPLKGRVVKASFR 265 >3D0N-A nrPDB Length = 264 Score = 357 bits (916), Expect = 3e-99, Method: Composition-based stats. Identities = 155/256 (60%), Positives = 192/256 (75%), Gaps = 1/256 (0%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGH 64 WGY +HNGP HW + FPIA G++QSP++I T KYD SL+PLS+ YD +++ I N+GH Sbjct: 8 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 67 Query: 65 AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN 124 +FNV+FDD+++K+VL+GGPL G+YRL Q H HWGS D GSEH VD YAAELH+VHWN Sbjct: 68 SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 127 Query: 125 T-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGL 183 + KY F +A +PDGLAVLG+FL++G LQK+ D LDSIK KGK FTNFD L Sbjct: 128 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 187 Query: 184 LPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDN 243 LP S DYWTYPGSLT PPLLE VTWIVLK+PI++SS+Q+ KFR L EGE +V N Sbjct: 188 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 247 Query: 244 WRPAQPLKNRQIKASF 259 RP QPLK R+++ASF Sbjct: 248 HRPPQPLKGRKVRASF 263 >6FAF-A nrPDB Length = 261 Score = 355 bits (911), Expect = 1e-98, Method: Composition-based stats. Identities = 155/256 (60%), Positives = 187/256 (73%), Gaps = 1/256 (0%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGH 64 WGY NGPE W K +PIA G QSPVDI T K+D SLKP+SVSY+ AT+ I+N GH Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH 65 Query: 65 AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN 124 +F+V F+D+ +++VLKGGP +YRL QFHFHWGS + GSEHTVD KY+AELH+ HWN Sbjct: 66 SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWN 125 Query: 125 T-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGL 183 + KY +A + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP L Sbjct: 126 SAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTL 185 Query: 184 LPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDN 243 LP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L N EG+ M N Sbjct: 186 LPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHN 245 Query: 244 WRPAQPLKNRQIKASF 259 RP QPLK R ++ASF Sbjct: 246 NRPTQPLKGRTVRASF 261 >1URT-A nrPDB Length = 248 Score = 328 bits (842), Expect = 1e-90, Method: Composition-based stats. Identities = 131/239 (54%), Positives = 167/239 (69%), Gaps = 1/239 (0%) Query: 23 AKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGG 82 A+G RQSP++I + YDP L PL VSYD A+ + N GHAF VEFDDS + + + GG Sbjct: 2 AEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISGG 61 Query: 83 PLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAVQQPDGLA 141 PL YRL QFHFHWG+ D GSEH VD Y AELHLVHWN TKY ++ KA +GLA Sbjct: 62 PLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLA 121 Query: 142 VLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPP 201 V+G+FLK+G+ LQK+VDVL ++ K +FDP L+P DYWTYPGSLTTPP Sbjct: 122 VIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRDYWTYPGSLTTPP 181 Query: 202 LLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 260 L E VTWIV K P+ VS Q+ FR L F+G GE E++MV+N+RP QPL++R++++SF+ Sbjct: 182 LAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR 240 >2W2J-A nrPDB Length = 291 Score = 298 bits (762), Expect = 2e-81, Method: Composition-based stats. Identities = 103/257 (40%), Positives = 155/257 (60%), Gaps = 15/257 (5%) Query: 16 WHKDFPIAKGERQSPVDIDTHTAKYDPSL--KPLSVSYDQATSLRILNNGHAFNVEFDDS 73 W FP A GE QSP+++++ A+YDPSL LS +Y + N+GH V Sbjct: 38 WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS- 96 Query: 74 QDKAVLKGGPLDG--TYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDF 130 K+VL GGPL + L + FHWG + +GSEHTV+ K + ELHL+HWN+ +G Sbjct: 97 --KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSI 154 Query: 131 GKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPES--L 188 +AV +P G+A++ +F+++G GL+ V ++L I+ KGKS F+P LLP+ Sbjct: 155 DEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLR 214 Query: 189 DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP-----EELMVDN 243 DYW Y GSLT PP E VTWI+ + P+++S Q+ +FR+L + +G + ++ DN Sbjct: 215 DYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDN 274 Query: 244 WRPAQPLKNRQIKASFK 260 +RP QPL +R I+A+F+ Sbjct: 275 FRPTQPLSDRVIRAAFQ 291 >4LU3-A nrPDB Length = 279 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 96/264 (36%), Positives = 135/264 (51%), Gaps = 12/264 (4%) Query: 3 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQAT--SLRI 59 HW Y +G +HW +P QSP+DI T + +DP L L YDQ L + Sbjct: 5 QHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDL 64 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQG-SEHTVDKKKYAAEL 118 NNGH + + L G L Y Q H HWG G SEH ++ + AEL Sbjct: 65 HNNGHTVQLSLP-----STLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAEL 119 Query: 119 HLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKP-GLQKVVDVLDSIKTKGKSADFT 176 H+VH+++ Y +A ++P GLAVLGI ++VG K + ++ L ++ K + Sbjct: 120 HIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVP 179 Query: 177 NFDPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGE 235 F+ R LLP+ L Y+ Y GSLTTPP + V W V +S EQ+ K + F+ E E Sbjct: 180 PFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEE 239 Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259 P +L+V N+R QPL R + ASF Sbjct: 240 PSKLLVQNYRALQPLNQRMVFASF 263 >1RJ5-A nrPDB Length = 261 Score = 295 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 95/264 (35%), Positives = 137/264 (51%), Gaps = 12/264 (4%) Query: 3 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQAT--SLRI 59 HHW Y +G +HW +P G+ QSP++I T + +DP L + YDQ L + Sbjct: 3 HHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPLDL 62 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDG-QGSEHTVDKKKYAAEL 118 NNGH + + L G L Y Q H HWG +GSEH ++ + AAEL Sbjct: 63 HNNGHTVQLSLPPT-----LHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAEL 117 Query: 119 HLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGS-AKPGLQKVVDVLDSIKTKGKSADFT 176 H+VH++++ Y +A Q+P GLAVLGI ++VG P ++ L I+ K + Sbjct: 118 HVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTSVP 177 Query: 177 NFDPRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGE 235 F R L P+ L+ ++ Y GSLTTPP + V W V +S Q+ K ++ + E + Sbjct: 178 PFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEED 237 Query: 236 PEELMVDNWRPAQPLKNRQIKASF 259 P E +V N+R QPL R I ASF Sbjct: 238 PSEPLVQNYRVPQPLNQRTIFASF 261 >5LL9-A nrPDB Length = 263 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 89/264 (33%), Positives = 132/264 (50%), Gaps = 13/264 (4%) Query: 4 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSV-SYDQATSLR--IL 60 W Y +G W K +P G QSP+D+ + +YD SL PL Y+ + + + + Sbjct: 3 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLT 62 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDG-QGSEHTVDKKKYAAELH 119 NNGH+ + + L Y Q H HWG+ + GSEHTV + +AAELH Sbjct: 63 NNGHSVKLNLPSD-----MHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELH 117 Query: 120 LVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNF 178 +VH+N+ Y D A + +GLAVL + +++GS P K+ L +K KG+ A F Sbjct: 118 IVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGF 177 Query: 179 DPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPE 237 + LLPE +Y+ Y GSLTTPP V W V + P+ +S EQ+L + + Sbjct: 178 NIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDP 237 Query: 238 EL--MVDNWRPAQPLKNRQIKASF 259 M++N+R Q R + SF Sbjct: 238 SPREMINNFRQVQKFDERLVYTSF 261 >5DVX-A nrPDB Length = 260 Score = 280 bits (716), Expect = 4e-76, Method: Composition-based stats. Identities = 95/261 (36%), Positives = 136/261 (52%), Gaps = 15/261 (5%) Query: 4 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSL---RIL 60 HW YG G W + P G QSPVDI A + P+L+PL +S Q L R+ Sbjct: 1 HWRYG---GDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLR 57 Query: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 NNGH+ + + +K GP YR +Q H HWG+ GSEHTV+ ++ AE+H+ Sbjct: 58 NNGHSVQLTLPPGLE---MKLGP-GREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHV 113 Query: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVG-SAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 VH +TKY +A+ +P GLAVL FL+ G ++++ L+ I +G D Sbjct: 114 VHLSTKYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLD 173 Query: 180 PRGLLPES-LDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 LLP Y+ Y GSLTTPP + V W V + +S+S++Q+ L+ G + Sbjct: 174 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQL---HTLSDTLWGPGDS 230 Query: 239 LMVDNWRPAQPLKNRQIKASF 259 + N+R QPL R I+ASF Sbjct: 231 RLQLNFRATQPLNGRVIEASF 251 >5JN8-A nrPDB Length = 266 Score = 274 bits (700), Expect = 3e-74, Method: Composition-based stats. Identities = 87/269 (32%), Positives = 126/269 (46%), Gaps = 16/269 (5%) Query: 2 SHHWGYGKHNGPEHWHKDFPI-----AKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQAT 55 HW Y ++ P+ + +RQSP++I T AK D L S YD+ Sbjct: 2 ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 61 Query: 56 SLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYA 115 + + NNGH+ + + +KA + GG L Y+ Q H HW L +GSEH++D + +A Sbjct: 62 TWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFA 118 Query: 116 AELHLVHWNTKYGD--FGKAVQQPDGLAVLGIFLKVG-SAKPGLQKVVDVLDSIKTKGKS 172 E+H+VH K +A D +AVL ++ G G Q +V+ L +I S Sbjct: 119 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMS 178 Query: 173 ADFTNFDPRGLLPES---LDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLN 229 LLP+ Y+ Y GSLTTP E V W V +EPI + EQ+L F + Sbjct: 179 TTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 238 Query: 230 FNGEGEPEELMVDNWRPAQPLKNRQIKAS 258 + + E M DN RP Q L R + S Sbjct: 239 Y-YDKEQTVSMKDNVRPLQQLGQRTVIKS 266 >4COQ-A nrPDB Length = 247 Score = 273 bits (698), Expect = 5e-74, Method: Composition-based stats. Identities = 98/258 (37%), Positives = 127/258 (49%), Gaps = 39/258 (15%) Query: 4 HWGYGKHNGPEHWHK---DFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HWGY GPEHW ++ + K G+ QSP+DI++ A L P+SV Y + + + Sbjct: 25 HWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADA-VKACLAPVSVYY-VSDAKYV 82 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 +NNGH V + V+ G + L QFHFH SEHTV+ K Y E H Sbjct: 83 VNNGHTIKVVM-GGRGYVVVDG----KRFYLKQFHFH------APSEHTVNGKHYPFEAH 131 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 VH + + VLG+F KVG P L+KV V+ K D Sbjct: 132 FVHLDKN-----------GNITVLGVFFKVGKENPELEKVWRVMPEEP-GQKRHLTARID 179 Query: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEEL 239 P LLPE+ DY+ Y GSLTTPP E V WIV KEP+ +S EQ+ KFRK+ Sbjct: 180 PEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVM---------- 229 Query: 240 MVDNWRPAQPLKNRQIKA 257 DN RP QPL R++ Sbjct: 230 GFDNNRPVQPLNARKVMK 247 >3FE4-A nrPDB Length = 278 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 92/263 (34%), Positives = 140/263 (53%), Gaps = 15/263 (5%) Query: 5 WGYGKHNGPE-HWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSV-SYD-QATSLRILN 61 W Y + E HW + +P G+RQSP+++ +Y+PSLK L++ Y+ QA ++N Sbjct: 4 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 63 Query: 62 NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWG--SLDGQGSEHTVDKKKYAAELH 119 NGH + + V G Y Q HFHWG S + GSEHTVD ++ E+H Sbjct: 64 NGHTVQISLPSTMRMTVADGT----VYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 119 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGS--AKPGLQKVVDVLDSIKTKGKSADFTN 177 +VH+N+KY + A PDGLAVL F++V + + L +IK G+ T Sbjct: 120 IVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG 179 Query: 178 FDPRGLLPESL-DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP 236 D + +LP +L Y+TY GSLTTPP E V W VL + + +S QV K + Sbjct: 180 LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHR--- 236 Query: 237 EELMVDNWRPAQPLKNRQIKASF 259 + + +++R QPL +R ++++F Sbjct: 237 NKTIHNDYRRTQPLNHRVVESNF 259 >3ZNC-A nrPDB Length = 258 Score = 268 bits (684), Expect = 2e-72, Method: Composition-based stats. Identities = 88/267 (32%), Positives = 120/267 (44%), Gaps = 24/267 (8%) Query: 5 WGYGKHN--------GPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPL-SVSYDQAT 55 W Y GPE W K +QSP++I T K +P L P V YDQ Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ 57 Query: 56 SLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYA 115 I NN H + A + GG L Y +Q H HW + + GSEH++D + +A Sbjct: 58 QWPIKNNQHTVEMTLGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFA 114 Query: 116 AELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSA-KPGLQKVVDVLDSIKTKGKSAD 174 E+H+VH D AVL ++VG G Q +V+ L SI ++ Sbjct: 115 MEMHIVHKKLT----SSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTST 170 Query: 175 FTNFDPRGLLPESLD---YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFN 231 + +LP S Y+ Y GSLTTP E V W V K+PI + Q L+F K + Sbjct: 171 VRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLY- 229 Query: 232 GEGEPEELMVDNWRPAQPLKNRQIKAS 258 + + + M DN RP QPL RQ+ S Sbjct: 230 YDEDQKLNMKDNVRPLQPLGKRQVFKS 256 >4X5S-A nrPDB Length = 232 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 95/259 (36%), Positives = 133/259 (51%), Gaps = 38/259 (14%) Query: 3 HHWGYGKHNGPEHWHK---DFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HHW Y NGPE+W K ++ + QSPVDI + K L+ L ++Y++A + I Sbjct: 8 HHWSYEGENGPENWAKLNPEYFWCNLKNQSPVDI-SDNYKVHAKLEKLHINYNKAVNPEI 66 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 +NNGH V + K +KG Y L QFHFH SEHTV+ K Y E+H Sbjct: 67 VNNGHTIQVNVLEDF-KLNIKG----KEYHLKQFHFH------APSEHTVNGKYYPLEMH 115 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 LVH + + +AV+G+F K G A P L KV +++K +G + + Sbjct: 116 LVHKD-----------KDGNIAVIGVFFKEGKANPELDKVFK--NALKEEGSKVFDGSIN 162 Query: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEEL 239 LLP +Y+TY GSLTTPP E V WIVLK+PI+ S +Q+ F+ + Sbjct: 163 INALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMK--------- 213 Query: 240 MVDNWRPAQPLKNRQIKAS 258 +N RP QP+ +R I S Sbjct: 214 -HNNNRPTQPINSRYILES 231 >4G7A-A nrPDB Length = 248 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 85/262 (32%), Positives = 124/262 (47%), Gaps = 38/262 (14%) Query: 1 MSHHWGYGKHNGPEHWHK---DFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSL 57 + H W Y GPEHW + +F K + QSP++ID K +L L++ Y A Sbjct: 22 LEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINID-KKYKVKANLPKLNLYYKTAKES 80 Query: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 ++NNGH + + L Y+L QFHFH SEHT++KK Y E Sbjct: 81 EVVNNGHTIQINIKEDNTLNY-----LGEKYQLKQFHFH------TPSEHTIEKKSYPLE 129 Query: 118 LHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTN 177 +H VH + + V+G+ K+G L K+++V + +G+ N Sbjct: 130 IHFVHKT-----------EDGKILVVGVMAKLGKTNKELDKILNVAPA--EEGEKILDKN 176 Query: 178 FDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPE 237 + L+P+ Y TY GSLTTPP E V WIVLK+PIS+S +Q+ K + + N Sbjct: 177 LNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVN------ 230 Query: 238 ELMVDNWRPAQPLKNRQIKASF 259 N RP Q + +R I F Sbjct: 231 ----PNNRPVQEINSRWIIEGF 248 >6EKI-A nrPDB Length = 226 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 86/259 (33%), Positives = 117/259 (45%), Gaps = 44/259 (16%) Query: 4 HWGYGKHNGPEHWH---KDFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HW Y GP+HW ++ + K G+ QSPVDI + + L+ + ++Y S I Sbjct: 5 HWSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDI---SRIVEAELEKIKINYSSGGS-SI 60 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 NNGH V ++ V + L QFHFH SEHT+ K Y E H Sbjct: 61 TNNGHTIKVSYEPGSYIIV-----DGIRFELKQFHFH------APSEHTIKGKSYPFEAH 109 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFT-NF 178 VH + LAV+G+ K G P ++K+ + L GK+ Sbjct: 110 FVH-----------ADKDGNLAVIGVIFKEGKKNPIIEKIWENLPE---AGKTIKLAHKI 155 Query: 179 DPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 + LLP+ Y+ Y GSLTTPP E V WIV++E + +S EQ+ KFRKL Sbjct: 156 NAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLM--------- 206 Query: 239 LMVDNWRPAQPLKNRQIKA 257 D RP QPL R I Sbjct: 207 -GGDTNRPVQPLNARMIME 224 >4XZ5-A nrPDB Length = 233 Score = 243 bits (619), Expect = 8e-65, Method: Composition-based stats. Identities = 78/260 (30%), Positives = 110/260 (42%), Gaps = 38/260 (14%) Query: 4 HWGYGKHNGPEHWHKDFP----IAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HWGY GP++W + P G+ QSP+++ TA SL V Y + T+L++ Sbjct: 3 HWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRE-TALKL 61 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 +NNGH V + +K Y L+Q+HFH SEH D Y E+H Sbjct: 62 INNGHTLQVNIPLG---SYIKING--HRYELLQYHFH------TPSEHQRDGFNYPMEMH 110 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 LVH + LAV+ I + G L K++ L K + + Sbjct: 111 LVHKD-----------GDGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKIH 159 Query: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEEL 239 P P ++ Y GSLTTPP E V W+V K+PI S Q+ K E Sbjct: 160 PAKFFPADKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMH-----------EY 208 Query: 240 MVDNWRPAQPLKNRQIKASF 259 + N RP Q R + S+ Sbjct: 209 LGSNARPVQRQNARTLLKSW 228 >5HPJ-A nrPDB Length = 217 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 110/256 (42%), Gaps = 41/256 (16%) Query: 4 HWGYGKHNGPEHWHKDFP-IAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNN 62 W Y +G EHW F A+G Q+P+DI+ T L PL + Y + ++NN Sbjct: 1 EWSYTGEHGTEHWGDSFATCAEGVNQTPIDINQTT---QAELAPLHLDY-EGQVTELVNN 56 Query: 63 GHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVH 122 GH V T+ L QFHFH SE+ + K+Y E H VH Sbjct: 57 GHTIQANLTGKNTLTV-----DGKTFELKQFHFH------TPSENYLKGKQYPLEAHFVH 105 Query: 123 WNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTN-FDPR 181 K LAV+ + G ++ +L SI +KG++ + +P Sbjct: 106 ATDK-----------GELAVVAVMFDFGPRSNN--ELTTLLASIPSKGQTVELKEALNPA 152 Query: 182 GLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMV 241 LLP +Y+ + GSLTTPP E V W V++EP + S Q K + +M Sbjct: 153 DLLPRDREYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQ-----------AVMG 201 Query: 242 DNWRPAQPLKNRQIKA 257 +N RP QPL R I Sbjct: 202 NNARPLQPLNARLILE 217 >1KOQ-A nrPDB Length = 223 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 115/258 (44%), Gaps = 41/258 (15%) Query: 4 HWGYGKHNGPEHWH---KDFPIA-KGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRI 59 HWGY H+ PE W ++F + G+ QSPV+I L + V+Y + + + + Sbjct: 3 HWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITET---VSGKLPAIKVNY-KPSMVDV 58 Query: 60 LNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119 NNGH V + + + + G TY L QFHFH SE+ + + + E H Sbjct: 59 ENNGHTIQVNYPEGGNTLTVNGR----TYTLKQFHFH------VPSENQIKGRTFPMEAH 108 Query: 120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 VH + +QP VL + + G L + +V+ T GK FD Sbjct: 109 FVHLDEN--------KQP---LVLAVLYEAGKTNGRLSSIWNVMP--MTAGKVKLNQPFD 155 Query: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEEL 239 LLP+ L Y+ + GSLTTPP E V+W+VLK + Q KF + + Sbjct: 156 ASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTR----------AV 205 Query: 240 MVDNWRPAQPLKNRQIKA 257 +N RP QPL R + Sbjct: 206 GSENNRPVQPLNARVVIE 223 >4XIW-A nrPDB Length = 239 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 84/262 (32%), Positives = 114/262 (43%), Gaps = 39/262 (14%) Query: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDI--DTHTAKYDPSLKPLSVSYDQATSLRILNN 62 W YG+ GP W A G+RQSP++I +T K D + +Y +LN Sbjct: 4 WNYGEVAGPPTWKGV--CATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFEKCDVLNT 61 Query: 63 GH-AFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121 GH V F + A + L L+QFHFH SEH +D ++YA E HLV Sbjct: 62 GHGTMQVNFPAG-NLAFIGNMEL----ELLQFHFH------APSEHAMDGRRYAMEAHLV 110 Query: 122 HWNTKYGDFGKAVQQPDGLAVLGIFLKVGS--AKPGLQKVVDVLDSIKTKGKSADFTNFD 179 H N + LAVLGI L+ G P L ++V + K + + Sbjct: 111 HKN----------KSTGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSP-KGIN 159 Query: 180 PRGLLPESLD-----YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEG 234 P LLP+ + YPGSLTTPP E V W V +PI V Q+L F + Sbjct: 160 PVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFV----- 214 Query: 235 EPEELMVDNWRPAQPLKNRQIK 256 + N RP Q L +R ++ Sbjct: 215 GDNKTYATNTRPLQLLNSRLVE 236 >4ETQ-X nrPDB Length = 269 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 80/231 (34%), Positives = 119/231 (51%), Gaps = 10/231 (4%) Query: 26 ERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLD 85 ++ SP++I+T A + LKPL + Y+++ I N G + F + GG L Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLP 58 Query: 86 GTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAVQQPDGLAVLG 144 Y L H +WG D GS H +D KY+ E++LVHWN KY + +A + DGL ++ Sbjct: 59 NEYVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 145 IFLKVGSA-KPGLQKVVDVLDSIKTKGKSADFTN-FDPRGLLPESLDYWTYPGSLTTPPL 202 IFL+V QK+V+ LDSI++ SA F + F LLP LDY+TY G TT Sbjct: 119 IFLQVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINH 176 Query: 203 LECVTWIVLKEPISVSSEQVLKFRKLNF-NGEGEPEELMVDNWRPAQPLKN 252 WI+ PI++ S+Q+ KFR L + + +N+R L + Sbjct: 177 SADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >4TWL-A nrPDB Length = 246 Score = 222 bits (567), Expect = 9e-59, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 112/263 (42%), Gaps = 36/263 (13%) Query: 1 MSHHWGY--GKHNGPEHWHKDFP----IAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQA 54 + + Y G NGPE+W P KG QSP+ + + +D +L L +Y +A Sbjct: 1 VEDEFSYIDGNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNY-RA 59 Query: 55 TSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKY 114 R+ N+GH V+F + + Y+L + HFH SEH ++ +++ Sbjct: 60 VDARLRNSGHDVLVDFKGNAGSLSIN----RVEYQLKRIHFH------SPSEHEMNGERF 109 Query: 115 AAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGK-SA 173 E LVH + Q AV+ I + G A P L + D + K Sbjct: 110 DLEAQLVHES-----------QDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEI 158 Query: 174 DFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGE 233 + DP L + Y+ Y GS T PP E ++W V+++ +VS QVL ++ Sbjct: 159 NAGVVDPNQLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQ------ 212 Query: 234 GEPEELMVDNWRPAQPLKNRQIK 256 E ++N RP QP R + Sbjct: 213 -AVNENAINNARPLQPTNFRSVF 234 >6B9J-X nrPDB Length = 241 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 80/231 (34%), Positives = 119/231 (51%), Gaps = 10/231 (4%) Query: 26 ERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLD 85 ++ SP++I+T A + LKPL + Y+++ I N G + F + GG L Sbjct: 3 QQLSPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLP 58 Query: 86 GTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWN-TKYGDFGKAVQQPDGLAVLG 144 Y L H +WG D GS H +D KY+ E++LVHWN KY + +A + DGL ++ Sbjct: 59 NEYVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIIS 118 Query: 145 IFLKVGSA-KPGLQKVVDVLDSIKTKGKSADFTN-FDPRGLLPESLDYWTYPGSLTTPPL 202 IFL+V QK+V+ LDSI++ SA F + F LLP LDY+TY G TT Sbjct: 119 IFLQVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINH 176 Query: 203 LECVTWIVLKEPISVSSEQVLKFRKLNF-NGEGEPEELMVDNWRPAQPLKN 252 WI+ PI++ S+Q+ KFR L + + +N+R L + Sbjct: 177 SADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >1Y7W-A nrPDB Length = 291 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 81/279 (29%), Positives = 114/279 (40%), Gaps = 38/279 (13%) Query: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTH--------TAKYDPSLKPLSVSYD 52 M H + + E +P G QSP+DI+T+ + SL L+V Sbjct: 26 MQHGFDWPGL--QEGGTTKYPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGA 83 Query: 53 QATSLRILNNG----HAFNVEFD-DSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEH 107 QA + + N V FD + + ++ G ++ IQFHFH SEH Sbjct: 84 QADGITLTNAKVDLEQGMKVTFDQPAANLPTIEIGGTTKSFVPIQFHFHHFL-----SEH 138 Query: 108 TVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLK--------VGSAKPGLQ-K 158 T++ Y ELH+V D A LAV+GI K + S + ++ K Sbjct: 139 TINGIHYPLELHIVMQEQDPADVATAQ-----LAVIGIMYKYSENGDAFLNSLQTQIEGK 193 Query: 159 VVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS 218 + D S G S D N + LLP SL Y Y GSLTTP E V W V P V+ Sbjct: 194 IGDGTASYGDTGVSIDNINVKTQ-LLPSSLKYAGYDGSLTTPGCDERVKWHVFTTPREVT 252 Query: 219 SEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKA 257 EQ+ F + + V N R Q L +R++ Sbjct: 253 REQMKLFVDVTMGAHAGAD---VVNNRMIQDLGDREVYK 288 >5TT3-A nrPDB Length = 234 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 72/260 (27%), Positives = 107/260 (41%), Gaps = 44/260 (16%) Query: 4 HWGY-GKHNGPEHW---HKDFPIAK-GERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLR 58 W Y K NGP W HKDF + K G+ QSP++I+ + D + L Y + Sbjct: 9 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKA--DLQFKYAASKPKA 66 Query: 59 ILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAEL 118 + H F+ + + +G Y L HFH E ++ K Sbjct: 67 VFFTHHTLKASFEPT-NHINYRGH----DYVLDNVHFH------APMEFLINNKTRPLSA 115 Query: 119 HLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNF 178 H VH + K L VL I + G P L +++ + K +F Sbjct: 116 HFVHKDAK-----------GRLLVLAIGFEEGKENPNLDPILEGIQ------KKQNFKEV 158 Query: 179 DPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEE 238 LP+S++Y+ + GSLT PP E V W V++EP+ VS++Q+ + +K N Sbjct: 159 ALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSP----- 213 Query: 239 LMVDNWRPAQPLKNRQIKAS 258 N RP QP N I S Sbjct: 214 ----NQRPVQPDYNTVIIKS 229 >3Q31-A nrPDB Length = 244 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 106/252 (42%), Gaps = 34/252 (13%) Query: 2 SHHWGYGKHNGPEHWHKD----FPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSL 57 ++ + Y GP +W+ AKG+ QSP+ ID+ Y S L + A Sbjct: 8 ANKFNYTGLGGPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAAS-GSLKLDLPLADGS 66 Query: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 ++ N G V + A K TY L QFHFH SEH V+++ + E Sbjct: 67 KLENLGFGLQVTLTNGSLTANSK------TYTLAQFHFH------TPSEHHVNEEHFPME 114 Query: 118 LHLVHWNTKYGDFGKAVQQPDGLAVLGIFL---KVGSAKPGLQKVVDVLDSIKTKGKSAD 174 +H V F A ++ AV+G F +VG + P V +D+I G S Sbjct: 115 VHFV--------FQTAAKET---AVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGTSTT 163 Query: 175 FTNFDPRGLLP--ESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRK-LNFN 231 D GLL + Y GSLTTPP E V W + EP+ ++ + K +K + +N Sbjct: 164 TGQLDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKIIKYN 223 Query: 232 GEGEPEELMVDN 243 L DN Sbjct: 224 ARYTQNALGQDN 235 >3B1B-A nrPDB Length = 377 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 72/263 (27%), Positives = 109/263 (41%), Gaps = 53/263 (20%) Query: 4 HWGYGKHNGPEHW------HKDFPIAKGERQSPVD------IDTHTAKYDPSLKPLSVSY 51 HW + NG E+W + G +QSP++ +D +K L+ SY Sbjct: 39 HWDH-GLNG-ENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQ-TQWSY 95 Query: 52 ----DQATSLRILNNGHAFNVEF-----------------DDSQDKAVLKGGPLDGTYRL 90 TS++++NNGH V++ ++ VL+ P D R+ Sbjct: 96 PDLMSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAADRV 155 Query: 91 ----IQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIF 146 QFHFH SEH + K Y ELH+VH T+ + K +V GI Sbjct: 156 TAVPTQFHFH------STSEHLLAGKIYPLELHIVHQVTEKLEACKG----GCFSVTGIL 205 Query: 147 LKV--GSAKPGLQKVVDVLDSIKTKGKSADF-TNFDPRGLLPESLDYWTYPGSLTTPPLL 203 ++ G L+ + + S + + T LLP DY TY GSLTTPP Sbjct: 206 FQLDNGPDNELLEPIFANMPSREGTFSNLPAGTTIKLGELLPSDRDYVTYEGSLTTPPCS 265 Query: 204 ECVTWIVLKEPISVSSEQVLKFR 226 E + W V+ +P +S Q ++R Sbjct: 266 EGLLWHVMTQPQRISFGQWNRYR 288 >1S7T-A nrPDB Length = 348 Score = 33.9 bits (76), Expect = 0.080, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 23/60 (38%), Gaps = 15/60 (25%) Query: 9 KHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNV 68 + GPE+W ++ AKG QS + L+ L Y+Q+ H V Sbjct: 53 EQEGPEYWERETQKAKGNEQS----------FRVDLRTLLGYYNQSKGGS-----HTIQV 97 >5OQL-U nrPDB Length = 582 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 60/177 (33%), Gaps = 32/177 (18%) Query: 37 TAKYDPSLKPL--SVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFH 94 K P L L + ++ +L + + + ++ + + G D +R I+ H Sbjct: 66 EGKVTPKLASLLNELKDEKKVTLAVHDTKLSNSITKLPGINIKPISGSMTDDLFRAIRQH 125 Query: 95 FHWGSLDGQGSEH-TVD-KKKYAAELH------------LVHWNTKYGDFGKAVQQPDGL 140 + + S ++ ++ H +VH + K L Sbjct: 126 LYNLIPGMEPSNFDEMNLGLAHSLSRHKLKFSPEKVDVMIVHAVALLDELDKE------L 179 Query: 141 AVLGIFLKV--GSAKPGLQKVVDVLDSIKTK------GKSADFTNFDPRGLLPESLD 189 V+ + +K G P L K++ D++ G + N D +LP ++ Sbjct: 180 NVMAMRVKEWYGWHFPELGKILP--DNLSYARVVLALGLRTNAPNADLSEILPPEIE 234 >5J6H-A nrPDB Length = 302 Score = 32.3 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 24/59 (40%), Gaps = 15/59 (25%) Query: 9 KHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFN 67 + GPE+W ++ AKG QS + SL+ L Y+Q+ S H Sbjct: 54 EQEGPEYWERETQRAKGNEQS----------FHVSLRTLLGYYNQSESGS-----HTIQ 97 >1BII-A nrPDB Length = 365 Score = 31.5 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 9 KHNGPEHWHKDFPIAKGERQS-PVDIDTHTAKYDPSLKP 46 + GPE+W ++ AKG QS VD+ T Y+ S Sbjct: 77 EQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGG 115 >5OQI-A nrPDB Length = 431 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 22/60 (36%), Gaps = 15/60 (25%) Query: 9 KHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNV 68 + GPE+W + AKG QS + L+ L Y+Q+ H V Sbjct: 195 EQEGPEYWERATQKAKGNEQS----------FRVDLRTLLGCYNQSKGGS-----HTIQV 239 >5KST-A nrPDB Length = 270 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 14/46 (30%) Query: 59 ILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQG 104 + N GH V D LD R Q H S+ G Sbjct: 23 LRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTP 68 >5TTH-B nrPDB Length = 672 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 19/50 (38%), Gaps = 4/50 (8%) Query: 207 TWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIK 256 W + EP +S Q +F + +P + +R PL R I Sbjct: 247 LW--MMEPKDISEWQHEEFYRYVAQAYDKPRYTLH--YRADAPLNIRSIF 292 >4OKD-A nrPDB Length = 840 Score = 28.8 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 2/54 (3%) Query: 156 LQKVVDVLDSIKTKGKSADFTNFDPRG--LLPESLDYWTYPGSLTTPPLLECVT 207 L V + +G + F D R +L +Y+ Y G T + V Sbjct: 341 LDVVFNHTAEGNERGPTISFRGLDNRVYYMLAPGGEYYNYSGCGNTLNCNQPVV 394 >3V65-B nrPDB Length = 386 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 33/109 (30%), Gaps = 15/109 (13%) Query: 45 KPLSVSYDQATSLRILNNGHAF-NVEFDDSQDKAVLKGGPLDGTYRLIQFH--FHW---- 97 L++ Y + H D S KAV+ G L + + F +W Sbjct: 249 NGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQG-LPHPFAITVFEDSLYWTDWH 307 Query: 98 -----GSLDGQGSEHTV--DKKKYAAELHLVHWNTKYGDFGKAVQQPDG 139 + G + +K + ++H +H + + G Sbjct: 308 TKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGG 356 >3V64-C nrPDB Length = 349 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 33/109 (30%), Gaps = 15/109 (13%) Query: 45 KPLSVSYDQATSLRILNNGHAF-NVEFDDSQDKAVLKGGPLDGTYRLIQFH--FHW---- 97 L++ Y + H D S KAV+ G L + + F +W Sbjct: 206 NGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQG-LPHPFAITVFEDSLYWTDWH 264 Query: 98 -----GSLDGQGSEHTV--DKKKYAAELHLVHWNTKYGDFGKAVQQPDG 139 + G + +K + ++H +H + + G Sbjct: 265 TKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGG 313 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.137 0.449 Lambda K H 0.267 0.0419 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,109,644 Number of Sequences: 36641 Number of extensions: 502041 Number of successful extensions: 1422 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 64 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1121 Number of HSP's gapped (non-prelim): 87 length of query: 260 length of database: 10,336,785 effective HSP length: 95 effective length of query: 165 effective length of database: 6,855,890 effective search space: 1131221850 effective search space used: 1131221850 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.9 bits)