BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00860 (461 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 7ODC-A nrPDB 886 0.0 1D7K-A nrPDB 819 0.0 1NJJ-A nrPDB 561 e-160 4ZGZ-A nrPDB 451 e-127 2NV9-A nrPDB 267 6e-72 5GJN-A nrPDB 220 1e-57 4AIB-A nrPDB 218 3e-57 2PLJ-A nrPDB 200 1e-51 2QGH-A nrPDB 102 5e-22 2P3E-A nrPDB 99 4e-21 2YXX-A nrPDB 96 4e-20 1TWI-A nrPDB 87 1e-17 3N2B-A nrPDB 87 1e-17 3VAB-A nrPDB 86 4e-17 4XG1-A nrPDB 75 7e-14 2J66-A nrPDB 72 3e-13 5X7M-A nrPDB 68 8e-12 1KNW-A nrPDB 43 2e-04 1HKV-A nrPDB 42 4e-04 3MT1-A nrPDB 42 5e-04 3N29-A nrPDB 40 0.002 3N2O-A nrPDB 39 0.003 3NZQ-A nrPDB 35 0.072 1VPB-A nrPDB 32 0.50 4G5E-A nrPDB 32 0.74 3CNO-A nrPDB 30 1.8 3HWC-A nrPDB 29 3.3 5V5P-C nrPDB 28 8.7 >7ODC-A nrPDB Length = 424 Score = 886 bits (2289), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/424 (99%), Positives = 424/424 (100%) Query: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP Sbjct: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 Query: 61 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI 120 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI Sbjct: 61 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI 120 Query: 121 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL 180 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL Sbjct: 121 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL 180 Query: 181 LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG 240 LERAKELNIDVIGVSFHVGSGCTDP+TFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG Sbjct: 181 LERAKELNIDVIGVSFHVGSGCTDPDTFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG 240 Query: 241 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ Sbjct: 241 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 Query: 301 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC 360 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC Sbjct: 301 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC 360 Query: 361 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI Sbjct: 361 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 Query: 421 QSHG 424 QSHG Sbjct: 421 QSHG 424 >1D7K-A nrPDB Length = 421 Score = 819 bits (2115), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/421 (92%), Positives = 402/421 (95%) Query: 7 DEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFY 66 +EFDCH LDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFY Sbjct: 1 EEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFY 60 Query: 67 AVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASN 126 AVKCNDS+AIV TLAA GTGFDCASKTEIQLVQ LGVP ER+IYANPCKQVSQIKYAA+N Sbjct: 61 AVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANN 120 Query: 127 GVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKE 186 GVQMMTFDSE+ELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATL+TSRLLLERAKE Sbjct: 121 GVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKE 180 Query: 187 LNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKL 246 LNIDV+GVSFHVGSGCTDPETFVQA+SDARCVFDM EVGFSM+LLDIGGGFPGSED KL Sbjct: 181 LNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKL 240 Query: 247 KFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDE 306 KFEEIT VINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKK V KEQ GSDDE Sbjct: 241 KFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDE 300 Query: 307 DESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRI 366 DES+EQTFMYYVNDGVYGSFNCILYDHAHVK LLQKRPKPDE+YYSSSIWGPTCDGLDRI Sbjct: 301 DESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDERYYSSSIWGPTCDGLDRI 360 Query: 367 VERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFP 426 VERC+LPEMHVGDWMLFENMGAYTVAAASTFNGFQRP IYYVMS P WQLM+Q Q+ FP Sbjct: 361 VERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFP 420 Query: 427 P 427 P Sbjct: 421 P 421 >1NJJ-A nrPDB Length = 425 Score = 561 bits (1445), Expect = e-160, Method: Compositional matrix adjust. Identities = 270/423 (63%), Positives = 328/423 (77%), Gaps = 2/423 (0%) Query: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 M D+ C L EGF +D L +KI+ +++ D+ D F+VADLGDI++KH W K LP Sbjct: 3 MDIVVNDDLSCRFL-EGFNTRDALCKKIS-MNTCDEGDPFFVADLGDIVRKHETWKKCLP 60 Query: 61 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI 120 RVTPFYAVKCND ++ TLAA+GTGFDCAS TEIQ V+G+GVP E++IYANPCKQ+S I Sbjct: 61 RVTPFYAVKCNDDWRVLGTLAALGTGFDCASNTEIQRVRGIGVPPEKIIYANPCKQISHI 120 Query: 121 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL 180 +YA +GV +MTFD EL KVA+ HPKAK+VLRI+TDDS A CRLSVKFGA ++ R + Sbjct: 121 RYARDSGVDVMTFDCVDELEKVAKTHPKAKMVLRISTDDSLARCRLSVKFGAKVEDCRFI 180 Query: 181 LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG 240 LE+AK+LNIDV GVSFHVGSG TD TF QA+SD+R VFDM TE+GF+MH+LDIGGGFPG Sbjct: 181 LEQAKKLNIDVTGVSFHVGSGSTDASTFAQAISDSRFVFDMGTELGFNMHILDIGGGFPG 240 Query: 241 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 + D LKFEEI VIN AL+K+FP D + I+AEPGRYYVASAFTLAVN+IAKK Q Sbjct: 241 TRDAPLKFEEIAGVINNALEKHFPPDLKLTIVAEPGRYYVASAFTLAVNVIAKKVTPGVQ 300 Query: 301 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC 360 ESN Q+FMYYVNDGVYGSFNCILYDHA V+ L Q+ P P+EK Y SS+WGPTC Sbjct: 301 TDVGAHAESNAQSFMYYVNDGVYGSFNCILYDHAVVRPLPQREPIPNEKLYPSSVWGPTC 360 Query: 361 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 DGLD+IVER LPEM VG+W+LFE+MGAYTV S+FNGFQ P IYYV+S +++++ Sbjct: 361 DGLDQIVERYYLPEMQVGEWLLFEDMGAYTVVGTSSFNGFQSPTIYYVVSGLPDHVVREL 420 Query: 421 QSH 423 +S Sbjct: 421 KSQ 423 >4ZGZ-A nrPDB Length = 438 Score = 451 bits (1160), Expect = e-127, Method: Compositional matrix adjust. Identities = 220/407 (54%), Positives = 293/407 (71%), Gaps = 5/407 (1%) Query: 13 ILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCND 72 +LDEG +++D + E + + K+AF+V DLG I+KKH +W + ++ PFY VKCN Sbjct: 15 LLDEGTDLGNVIDNYVYEHTLTG-KNAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNS 73 Query: 73 SRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMT 132 + A++ LAA+GTGF C+SK E+ LVQ LGVP E +IY +PCKQVSQIKYAA GV ++T Sbjct: 74 APAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILT 133 Query: 133 FDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVI 192 D+EIEL K+AR HP AK++L IAT+D+ ++KFG TLK R LLE AKEL++ +I Sbjct: 134 CDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKNCRHLLECAKELDVQII 193 Query: 193 GVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEIT 252 GV FHV S C + + +V A+SDARCVFDMA E+GF+M++LDIGGGF G+E + EE+ Sbjct: 194 GVKFHVSSACKESQVYVHALSDARCVFDMAGEIGFTMNMLDIGGGFTGTE---FQLEEVN 250 Query: 253 SVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ-PGSDDEDESNE 311 VI+P LD YFP SGV+II+EPG YYV+SAFTLAVNIIAKK V ++ P ++ S+E Sbjct: 251 HVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEKTGSDE 310 Query: 312 QTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCN 371 FMYY+NDGVYGSF L + + + K+ K DE ++SS+WGP+CD LD+IVE C Sbjct: 311 PAFMYYMNDGVYGSFASKLSEDLNTIPEVHKKYKEDEPLFTSSLWGPSCDELDQIVESCL 370 Query: 372 LPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMK 418 LPE++VGDW++F+NMGA + S FN FQRP IYY+MS W M+ Sbjct: 371 LPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQ 417 >2NV9-A nrPDB Length = 372 Score = 267 bits (683), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 135/355 (38%), Positives = 201/355 (56%), Gaps = 15/355 (4%) Query: 54 RWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANP 113 +W PRVTP YAVKCN+ ++ T+ FDCAS +EI+ V +GV R+I+A+ Sbjct: 33 QWTILFPRVTPHYAVKCNNDEVLLKTMCDKNVNFDCASSSEIKKVIQIGVSPSRIIFAHT 92 Query: 114 CKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGAT 173 K + + +A GV + TFDS EL K+ HP K++LRI DD A +L KFGA Sbjct: 93 MKTIDDLIFAKDQGVDIATFDSSFELDKIHTYHPNCKMILRIRCDDPNAAVQLGNKFGAN 152 Query: 174 LKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLD 233 R LLE AK+L+I+VIG+SFHVGSG +PE + +A+ ++ F+ A VG ++LD Sbjct: 153 EDEIRHLLEYAKQLDIEVIGISFHVGSGSRNPEAYYRAIKSSKEAFNEAISVGHKPYILD 212 Query: 234 IGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAK 293 IGGG D ++ IN A+ +FP D+ V I+AEPGR++ LA +I K Sbjct: 213 IGGGLHADIDEGELSTYMSDYINDAIKDFFPEDT-VTIVAEPGRFFAEHYSVLATQVIGK 271 Query: 294 KTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSS 353 + + + Y+ N+ YG F+ ++++ + L + DE+Y S Sbjct: 272 RV--------------RDGLYEYFFNESTYGGFSNVIFEKSVPTPQLLRDVPDDEEYVPS 317 Query: 354 SIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYV 408 ++G TCDG+D I LPE+H+GDW+ F + GAYT ++FNGF ++YY+ Sbjct: 318 VLYGCTCDGVDVINHNVALPELHIGDWVYFPSWGAYTNVLTTSFNGFGEYDVYYI 372 >5GJN-A nrPDB Length = 393 Score = 220 bits (561), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 131/367 (35%), Positives = 200/367 (54%), Gaps = 31/367 (8%) Query: 40 FYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQ 99 F VA L + + + + LPR FYA+K N + I+S LA +G+ FD AS E++++ Sbjct: 22 FLVASLDKVEENYQFMRRHLPRAGVFYAMKANPTPEILSLLAGLGSHFDVASAGEMEILH 81 Query: 100 GLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDD 159 LGV ++IYANP K +K AA V+ TFD E+ K+A+A P A +++RIA + Sbjct: 82 ELGVDGSQMIYANPVKDARGLKAAADYNVRRFTFDDPSEIDKMAKAVPGADVLVRIAVRN 141 Query: 160 SKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVF 219 +KA+ L+ KFGA ++ + LL+ A++ + +G+ FHVGS + +A+ AR +F Sbjct: 142 NKALVDLNTKFGAPVEEALDLLKAAQDAGLHAMGICFHVGSQSLSTAAYEEALLVARRLF 201 Query: 220 DMATEVGFSMHLLDIGGGFPGSEDTKLKFE--EITSVINPALDKYFPSDSGVRIIAEPGR 277 D A E+G + LDIGGGFP + L + + IN +D+ FP + + EPGR Sbjct: 202 DEAEEMGMHLTDLDIGGGFPVPDAKGLNVDLAAMMEAINKQIDRLFPDTA---VWTEPGR 258 Query: 278 YYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDH---- 333 Y +A L ++I KT EQP Y +++G+YG F+ I+YDH Sbjct: 259 YMCGTAVNLVTSVIGTKT-RGEQP-------------WYILDEGIYGCFSGIMYDHWTYP 304 Query: 334 AHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAA 393 H K+P S+ GP+CDG+D + PE+ +GD +L MG+YT + Sbjct: 305 LHCFGKGNKKP--------STFGGPSCDGIDVLYRDFMAPELKIGDKVLVTEMGSYTSVS 356 Query: 394 ASTFNGF 400 A+ FNGF Sbjct: 357 ATRFNGF 363 >4AIB-A nrPDB Length = 395 Score = 218 bits (556), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 129/389 (33%), Positives = 205/389 (52%), Gaps = 21/389 (5%) Query: 28 INEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGF 87 I++ + F++ D + K RW K +P V P +AVKCN +V L +G GF Sbjct: 16 ISQFEPENQPLGFWIFDTEGVEKAVERWKKNMPTVRPCFAVKCNPEPHLVKLLGELGCGF 75 Query: 88 DCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHP 147 DCAS EI+ V LG E + Y+ K +Q+ A+ G+ DS E+ K+A+ P Sbjct: 76 DCASLNEIKEVLDLGFNPEDITYSQTFKPYNQLIEASHLGINHTIVDSIDEVQKIAKYAP 135 Query: 148 KAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPET 207 K +++RI +D+ A KFG ++L+ K+ +++ GV FHVGS + E Sbjct: 136 KMGIMIRIMENDTSAGHVFGEKFGLHDDEVEIVLKEIKDKGLNLDGVHFHVGSDSHNSEV 195 Query: 208 FVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKY-FPSD 266 F +A++ AR +A + G +L+DIGGGF FEE + I + + FP Sbjct: 196 FTKALTKARNTVTLAEQFGMKPYLIDIGGGF----SQVAPFEEFAATIEKTIKELEFPER 251 Query: 267 SGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSF 326 + R IAEPGRY ++AF L ++ K+ ++ ++ Y DG++GSF Sbjct: 252 T--RFIAEPGRYMASNAFHLVSSLHGKRV----------RIQNGKKQIEYTSGDGLHGSF 299 Query: 327 N-CILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVG-DWMLFE 384 CI ++ + ++ + K Y S I+GP+C+G D++ + LPEM G DW+LF Sbjct: 300 GCCIWFEKQKSCECITQKVNENTKMYESIIYGPSCNGSDKVATQ-ELPEMEPGKDWLLFP 358 Query: 385 NMGAYTVAAASTFNGFQRPNIYYVMSRPM 413 NMGAYT++ A+ FNGF+ N + + + P+ Sbjct: 359 NMGAYTISMATNFNGFEERN-HVIYTLPL 386 >2PLJ-A nrPDB Length = 419 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 125/359 (34%), Positives = 196/359 (54%), Gaps = 23/359 (6%) Query: 47 DILKKHLRWLK-ALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPA 105 D++++ R LK ALP VT YA+K +V TL A G FD A+ E++LV GVPA Sbjct: 63 DVIRQQYRALKNALPNVTLHYALKPLPHPVVVRTLLAEGASFDLATTGEVELVASEGVPA 122 Query: 106 ERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCR 165 + I+ +P K+ + I+ A + G + D+ EL K +L++R++ +S+A Sbjct: 123 DLTIHTHPIKRDADIRDALAYGCNVFVVDNLNELEKFKAYRDDVELLVRLSFRNSEAFAD 182 Query: 166 LSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEV 225 LS KFG + + + +++E AKE NI + G+SFHVGS T+P +V+A+ R V + E Sbjct: 183 LSKKFGCSPEQALVIIETAKEWNIRIKGLSFHVGSQTTNPNKYVEAIHTCRHVMEQVVER 242 Query: 226 GF-SMHLLDIGGGFPGSEDTK-LKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASA 283 G ++ LDIGGGFP + + + ++ + IN AL P V ++AEPGR+ A A Sbjct: 243 GLPALSTLDIGGGFPVNYTQQVMPIDQFCAPINEAL-SLLPET--VHVLAEPGRFICAPA 299 Query: 284 FTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKR 343 T +++ + E YY++DG+YGSF+ +++D A K+ Sbjct: 300 VTSVASVMGQA--------------EREGQIWYYLDDGIYGSFSGLMFDDARYPLTTIKQ 345 Query: 344 PKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQR 402 + S + GPTCD +D I E LP+++ GD ++ MGAYT A A+ FN F+R Sbjct: 346 ---GGELIPSVLSGPTCDSVDVIAENILLPKLNNGDLVIGRTMGAYTSATATDFNFFKR 401 >2QGH-A nrPDB Length = 425 Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 97/387 (25%), Positives = 164/387 (42%), Gaps = 44/387 (11%) Query: 37 KDAFYVADLGDILKKHLRWLKALPRVTPF--YAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 K FY+ D I + L + +A YA+K N + +I+S LA + +G DC S E Sbjct: 32 KTPFYLYDFDKIKQAFLNYKEAFKGRKSLICYALKANSNLSILSLLAHLESGADCVSIGE 91 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHP----KAK 150 IQ G+ R++++ K +I+ A + + +S +EL + KA+ Sbjct: 92 IQRALKAGIKPYRIVFSGVGKSAFEIEQALKLNILFLNVESFMELKTIETIAQSLGIKAR 151 Query: 151 LVLRIATD-DSKAVCRLSV-----KFGATLKTS-RLLLERAKELNIDVIGVSFHVGSGCT 203 + +RI + D+K +S KFG K + + L K ++ + V FH+GS Sbjct: 152 ISIRINPNIDAKTHPYISTGLKENKFGVGEKEALEMFLWAKKSAFLEPVSVHFHIGSQLL 211 Query: 204 DPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGS---EDTKLKFEEITSVINP--A 258 D E ++A + +G + D+GGG S E+T ++ ++N Sbjct: 212 DLEPIIEASQKVAKIAKSLIALGIDLRFFDVGGGIGVSYENEETIKLYDYAQGILNALQG 271 Query: 259 LDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYV 318 LD + II EPGR VA + L ++ +K ++ V Sbjct: 272 LD--------LTIICEPGRSIVAESGELITQVLYEKKAQNKR--------------FVIV 309 Query: 319 NDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVG 378 + G+ LY H A+ P + + GP C+ D ++ +LPE+ G Sbjct: 310 DAGMNDFLRPSLYHAKH--AIRVITPSKGREISPCDVVGPVCESSDTFLKDAHLPELEPG 367 Query: 379 DWMLFENMGAYTVAAASTFNGFQRPNI 405 D + E +GAY + AS +N RP + Sbjct: 368 DKIAIEKVGAYGSSMASQYN--SRPKL 392 >2P3E-A nrPDB Length = 420 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 97/377 (25%), Positives = 166/377 (44%), Gaps = 36/377 (9%) Query: 40 FYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQ 99 YV I ++ + KA P YAVK N + +V L +G G D S E+ L + Sbjct: 36 LYVYSSNFIKERFEAYRKAFPDALICYAVKANFNPHLVKLLGELGAGADIVSGGELYLAK 95 Query: 100 GLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKV----ARAHPKAKLVLRI 155 G+P ER++YA K ++ A + + M +S EL + + KA++ +R+ Sbjct: 96 KAGIPPERIVYAGVGKTEKELTDAVDSEILMFNVESRQELDVLNEIAGKLGKKARIAIRV 155 Query: 156 ATD-DSK-----AVCRLSVKFGATLKTSRLLLERAKEL-NIDVIGVSFHVGSGCTDPETF 208 D D K A KFG ++ ++ E A +L N++++G+ H+GS D + Sbjct: 156 NPDVDPKTHPYIATGMQKSKFGVDIREAQKEYEYASKLENLEIVGIHCHIGSQILDISPY 215 Query: 209 VQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSG 268 +AV +++ T+ GF + LDIGGG K K E+ D Sbjct: 216 REAVEKVVSLYESLTQKGFDIKYLDIGGGL----GIKYKPEDKEPAPQDLADLLKDLLEN 271 Query: 269 V--RIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSF 326 V +II EPGR + +A I+ + + + GS + F+ V+ G+ Sbjct: 272 VKAKIILEPGRSIMGNA-----GILITQVQFLKDKGS--------KHFI-IVDAGMNDLI 317 Query: 327 NCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENM 386 +Y+ H ++ + + K + I GP C+ D + + E+ G+++ + Sbjct: 318 RPSIYNAYHHIIPVETK---ERKKVVADIVGPICETGDFLALDREIEEVQRGEYLAVLSA 374 Query: 387 GAYTVAAASTFNGFQRP 403 GAY A +S +N RP Sbjct: 375 GAYGFAMSSHYN--MRP 389 >2YXX-A nrPDB Length = 386 Score = 95.9 bits (237), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 99/372 (26%), Positives = 165/372 (44%), Gaps = 50/372 (13%) Query: 47 DILKKHLRWLKAL---PRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGV 103 + L+K R +K + + P +AVK N++ ++ L G G D +K E+ + GV Sbjct: 21 ETLRKRSRLVKEVFEGVNLLPTFAVKANNNPVLLKILREEGFGMDVVTKGELLAAKLAGV 80 Query: 104 PAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARA-HPKA-KLVLRIATD-DS 160 P+ V++ K Q+++ V+++ DS E M++ R +P+ + +R+ + D+ Sbjct: 81 PSHTVVWNGNGKSRDQMEHFLREDVRIVNVDS-FEEMEIWRELNPEGVEYFIRVNPEVDA 139 Query: 161 KAVCRLSV-----KFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDA 215 K +S KFG L+ +ER + +NI G+ H+GS T E FV+A S Sbjct: 140 KTHPHISTGLKKHKFGIPLEDLDSFMERFRSMNIR--GLHVHIGSQITRVEPFVEAFSK- 196 Query: 216 RCVFDMATEVGFSMHLLDIGGG----FPGSEDTKLKFEEITSVINPALDKYFPSDSGVRI 271 V + GF ++IGGG + G E L + P L ++ R+ Sbjct: 197 --VVRASERYGFEE--INIGGGWGINYSGEE---LDLSSYREKVVPDLKRF------KRV 243 Query: 272 IAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILY 331 I E GRY VA + L + ++ K + + F+ V+ G+ LY Sbjct: 244 IVEIGRYIVAPSGYLLLRVVLVK-------------RRHNKAFV-VVDGGMNVLIRPALY 289 Query: 332 DHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTV 391 H +L K+ K + + GP C+ D I LPE+ GD + EN GAY Sbjct: 290 SAYHRIFVLGKQGKE----MRADVVGPLCESGDVIAYDRELPEVEPGDIIAVENAGAYGY 345 Query: 392 AAASTFNGFQRP 403 ++ +N RP Sbjct: 346 TMSNNYNSTTRP 357 >1TWI-A nrPDB Length = 434 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 92/363 (25%), Positives = 159/363 (43%), Gaps = 48/363 (13%) Query: 66 YAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAAS 125 YA K N + AI LA +G G D S E+ + + VP++++++ CK +I Sbjct: 66 YAYKANANLAITRLLAKLGCGADVVSGGELYIAKLSNVPSKKIVFNGNCKTKEEIIMGIE 125 Query: 126 NGVQMMTFDSEIELMKVA--------------RAHPKA--KLVLRIATDDSKAVCRLSVK 169 ++ DS EL+ + R +P K +I+T K L V+ Sbjct: 126 ANIRAFNVDSISELILINETAKELGETANVAFRINPNVNPKTHPKISTGLKKNKFGLDVE 185 Query: 170 FGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEV---G 226 G +K ++ LE ++V+GV H+GS TD F++ + R V D E+ G Sbjct: 186 SGIAMKAIKMALEMEY---VNVVGVHCHIGSQLTDISPFIE---ETRKVMDFVVELKEEG 239 Query: 227 FSMHLLDIGGGF--PGSEDTKLKFEE--ITSVINPALDKYFPSDSGVRIIAEPGRYYVAS 282 + +++GGG P +D ++ ++ ++IN L KY +I EPGR VA+ Sbjct: 240 IEIEDVNLGGGLGIPYYKDKQIPTQKDLADAIINTML-KYKDKVEMPNLILEPGRSLVAT 298 Query: 283 AFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQK 342 A L + K KE P T ++ G+ +Y+ H ++ Sbjct: 299 AGYL----LGKVHHIKETP----------VTKWVMIDAGMNDMMRPAMYEAYH--HIINC 342 Query: 343 RPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQR 402 + K +++ SI G C+ D L ++ VGD + ++GAY ++ A+ +N R Sbjct: 343 KVKNEKEVV--SIAGGLCESSDVFGRDRELDKVEVGDVLAIFDVGAYGISMANNYNARGR 400 Query: 403 PNI 405 P + Sbjct: 401 PRM 403 >3N2B-A nrPDB Length = 441 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 92/355 (25%), Positives = 150/355 (42%), Gaps = 33/355 (9%) Query: 66 YAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAAS 125 YAVK N + +++TLA +G+GFD S E++ V G +V+++ K +++K A Sbjct: 82 YAVKANSNLGVLNTLARLGSGFDIVSVGELERVLAAGGDPSKVVFSGVGKTEAEMKRALQ 141 Query: 126 NGVQMMTFDSEIELMKVARAHP----KAKLVLRIATD-DSKAVCRLSV-----KFGATLK 175 ++ +SE EL ++ + KA + LRI D D+K +S KFG T Sbjct: 142 LKIKCFNVESEPELQRLNKVAGELGVKAPISLRINPDVDAKTHPYISTGLRDNKFGITFD 201 Query: 176 TSRLLLERAKEL-NIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDI 234 + + A L N+DV G+ H+GS T F+ A + D G + LD+ Sbjct: 202 RAAQVYRLAHSLPNLDVHGIDCHIGSQLTALAPFIDATDRLLALIDSLKAEGIHIRHLDV 261 Query: 235 GGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKK 294 GGG +L + S AL + +I EPGR A+A L + K Sbjct: 262 GGGLGVVYRDELPPQ--PSEYAKALLDRLERHRDLELIFEPGRAIAANAGVLVTKVEFLK 319 Query: 295 TVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSS 354 + N +ND + + D ++ RP+ E + Sbjct: 320 HT----------EHKNFAIIDAAMNDLIRPALYQAWQD------IIPLRPRQGEA-QTYD 362 Query: 355 IWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVM 409 + GP C+ D + + +L + GD + + GAY +S +N RP + VM Sbjct: 363 LVGPVCETSDFLGKDRDLV-LQEGDLLAVRSSGAYGFTMSSNYN--TRPRVAEVM 414 >3VAB-A nrPDB Length = 443 Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 94/351 (26%), Positives = 154/351 (43%), Gaps = 41/351 (11%) Query: 66 YAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAAS 125 YA+K N ++A+++ LA +G G D S+ EI+ G+PA R++++ K ++ +A Sbjct: 79 YALKANSNQAVLTALAKLGAGADTVSQGEIRRALAAGIPANRIVFSGVGKTPREMDFALE 138 Query: 126 NGVQMMTFDSEIEL-MKVARAHPKAKLV---LRIATD-DSKAVCRLSV-----KFGATLK 175 G+ +SE EL + ARA K+ LRI D D+K ++S KFG Sbjct: 139 AGIYCFNVESEPELEILSARAVAAGKVAPVSLRINPDVDAKTHAKISTGKSENKFGIPRD 198 Query: 176 TSRLLLERAKEL-NIDVIGVSFHVGSGCTDPETFVQAVS-DARCVFDMATEVGFSMHLLD 233 +R RA L ++V+G+ H+GS D E F A + A V ++ + G ++ +D Sbjct: 199 KARAAYARAASLPGLNVVGIDMHIGSQIIDLEPFDNAFALMAELVKELQAD-GHNIRHVD 257 Query: 234 IGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAK 293 +GGG G V + G++ + EPGR V +A L +I Sbjct: 258 VGGGL-GIPYRTPNTPPPPPVAYAQIVAKHIKPLGLKTVFEPGRLIVGNAGLLVTEVIFV 316 Query: 294 KTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAH-VKALLQKRPKPDEKYYS 352 K E + + F+ V+ + LYD H ++ ++ P + Sbjct: 317 K-------------EGDAKNFV-IVDAAMNDLIRPTLYDAFHDIRPVIM--PNDNAPRIR 360 Query: 353 SSIWGPTCD-----GLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFN 398 + GP C+ GLDR V + GD + GAY +ST+N Sbjct: 361 ADFVGPVCETGDYLGLDREVAKPA-----PGDLIAICTTGAYGAVLSSTYN 406 >4XG1-A nrPDB Length = 427 Score = 74.7 bits (182), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 89/351 (25%), Positives = 163/351 (46%), Gaps = 41/351 (11%) Query: 66 YAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAAS 125 YAVK N + A+++ +A +G+GFD S E+ V G ++++++ K +I A Sbjct: 58 YAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQ 117 Query: 126 NGVQMMTFDSEIELMK---VARA-HPKAKLVLRIATD-DSKAVCRLSV-----KFGATLK 175 + +S EL + VA+A + KA + +RI + D+ +S KFG ++ Sbjct: 118 ANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKENKFGIEIE 177 Query: 176 TSRLLLERAKELN-IDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDI 234 + + + A +L +++ GV H+GS T+ F++A+ + D+ E G ++ LD+ Sbjct: 178 QALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDL 237 Query: 235 GGGF--PGSEDTKLK-FEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNII 291 GGG P ++T + E +T++IN + +++I EPGR +A+A L + Sbjct: 238 GGGLGVPYDDETPPEPAEYMTAIINRMAGR------SLKLIFEPGRAIMANAGVLVTKVE 291 Query: 292 AKKTVWKEQPGSDDEDESNEQTFMYYVND----GVYGSFNCILYDHAHVKALLQKRPKPD 347 K D N +ND +Y ++ I+ + + Q RP Sbjct: 292 FLKL----------NDYKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQD-GQDRP--- 337 Query: 348 EKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFN 398 S I GP C+ D + + L + GD+++ + GAY +S +N Sbjct: 338 --VRSYDIVGPICETGDFLGKERQLA-LAEGDYLVIRSTGAYGSTMSSNYN 385 >2J66-A nrPDB Length = 428 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 84/391 (21%), Positives = 161/391 (41%), Gaps = 69/391 (17%) Query: 40 FYVADLGDILKKHLRWLKAL--PRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQL 97 FY+ D GD ++ H R L++ P + + ++K N++ + G G + AS E+ L Sbjct: 19 FYLYD-GDFIEAHYRQLRSRTNPAIQFYLSLKANNNIHLAKLFRQWGLGVEVASAGELAL 77 Query: 98 VQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPK----AKLVL 153 + G AE +I++ P K+ S+++ A +G+ + +S EL + K A++ + Sbjct: 78 ARHAGFSAENIIFSGPGKKRSELEIAVQSGIYCIIAESVEELFYIEELAEKENKTARVAI 137 Query: 154 RIATDDSKAVCRLSV-----KFGATLKTSRLLLERAKELNI-DVIGVSFHVGSGCTDPET 207 RI D S + + +FG +++ + L IG+ + G+ + ++ Sbjct: 138 RINPDKSFGSTAIKMGGVPRQFGMDESMLDAVMDAVRSLQFTKFIGIHVYTGTQNLNTDS 197 Query: 208 FVQA----VSDARCVFDMATEVGFSMHLLDIGGGFP---GSEDTKLKFEEITSVIN---- 256 +++ V R +++ G +++GGGF S + L +IT ++ Sbjct: 198 IIESMKYTVDLGRNIYE---RYGIVCECINLGGGFGVPYFSHEKALDIGKITRTVSDYVQ 254 Query: 257 PALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMY 316 A D FP + I E GRY +A A ++ +K E ++ Sbjct: 255 EARDTRFPQTT---FIIESGRYLLAQAAVYVTEVLYRKASKGE---------------VF 296 Query: 317 YVNDGVYGSFNCILYDHAHVKALLQKRPK----PDE-----------KYYSSSIWGPTCD 361 + DG H H + + R P E + +I GP C Sbjct: 297 VIVDGGM---------HHHAASTFRGRSMRSNYPMEYIPVREDSGRRELEKVTIAGPLCT 347 Query: 362 GLDRIVERCNLPEMHVGDWMLFENMGAYTVA 392 D + + ++P ++ GD + N GAY ++ Sbjct: 348 PEDCLGKDVHVPALYPGDLVCVLNSGAYGLS 378 >5X7M-A nrPDB Length = 453 Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 88/375 (23%), Positives = 160/375 (42%), Gaps = 33/375 (8%) Query: 66 YAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAAS 125 YA K ++ I + G D AS E+ + G PA R+ K V ++ Sbjct: 72 YASKAFLTKTIARWVDEEGLALDIASINELGIALAAGFPASRITAHGNNKGVEFLRALVQ 131 Query: 126 NGVQMMTFDS--EIELMK-VARAHPKAKLVL-RIA------TDDSKAVCRLSVKFGATLK 175 NGV + DS E+EL+ VA K + VL R+ T + A KFG +L Sbjct: 132 NGVGHVVLDSAQELELLDYVAAGEGKIQDVLIRVKPGIEAHTHEFIATSHEDQKFGFSLA 191 Query: 176 TSR---LLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFD-MATEVGFSMHL 231 + N++++G+ HVGS D E F A ++ + +E+G ++ Sbjct: 192 SGSAFEAAKAANNAENLNLVGLHCHVGSQVFDAEGFKLAAERVLGLYSQIHSELGVALPE 251 Query: 232 LDIGGGFP---GSEDTKLKFEEITSVINPALDKYFPSDSGV---RIIAEPGRYYVASAFT 285 LD+GGG+ + + L E+ S + A+ K ++ G+ ++ EPGR Sbjct: 252 LDLGGGYGIAYTAAEEPLNVAEVASDLLTAVGK-MAAELGIDAPTVLVEPGR-------- 302 Query: 286 LAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPK 345 A+ + T+++ D + ++ V+ G+ + LY + ++ + + Sbjct: 303 -AIAGPSTVTIYEVGTTKDVHVDDDKTRRYIAVDGGMSDNIRPALYGSEYDARVVSRFAE 361 Query: 346 PDEKYYSSSIWGPTCDGLDRIVERCNLP-EMHVGDWMLFENMGAYTVAAASTFNGFQRPN 404 D S+ I G C+ D ++ P ++ GD++ GAY A +S +N F RP Sbjct: 362 GDP--VSTRIVGSHCESGDILINDEIYPSDITSGDFLALAATGAYCYAMSSRYNAFTRPA 419 Query: 405 IYYVMSRPMWQLMKQ 419 + V + ++++ Sbjct: 420 VVSVRAGSSRLMLRR 434 >1KNW-A nrPDB Length = 425 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 49/230 (21%), Positives = 90/230 (39%), Gaps = 29/230 (12%) Query: 181 LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGF-- 238 L+ + ++ ++G+ H+GSG + + E G + + GGG Sbjct: 175 LDVIQRHHLQLVGIHMHIGSGVD----YAHLEQVCGAMVRQVIEFGQDLQAISAGGGLSV 230 Query: 239 PGSE-DTKLKFEEITSVINPALDKYFPS-DSGVRIIAEPGRYYVASAFTLAVNIIAKKTV 296 P + + + E + N A ++ V++ EPGR+ VA + L + + K + Sbjct: 231 PYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQM 290 Query: 297 WKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALL-QKRPKPDEKYYSSSI 355 D F + +YGS++ H+ AL R + + Sbjct: 291 GSRHFVLVDAG------FNDLMRPAMYGSYH-------HISALAADGRSLEHAPTVETVV 337 Query: 356 WGPTCDGLDRI-------VERCNLPEMHVGDWMLFENMGAYTVAAASTFN 398 GP C+ D VE LPE+ GD+++ + GAY + +S +N Sbjct: 338 AGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYN 387 >1HKV-A nrPDB Length = 453 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 79/377 (20%), Positives = 140/377 (37%), Gaps = 55/377 (14%) Query: 66 YAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAAS 125 YA K + ++ G D + E+ + P ER+ K VS++ A Sbjct: 69 YAAKAFLCSEVARWISEEGLCLDVCTGGELAVALHASFPPERITLHGNNKSVSELTAAVK 128 Query: 126 NGVQMMTFDSEIELMKVARAHPKAKLV------------------LRIATDDSKAVCRLS 167 GV + DS E+ ++ +A +V + A +D K LS Sbjct: 129 AGVGHIVVDSMTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFISTAHEDQK--FGLS 186 Query: 168 VKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVF-DMATEVG 226 V GA + R + ++ ++G+ H+GS D + F A + D+ E G Sbjct: 187 VASGAAMAAVRRVFATD---HLRLVGLHSHIGSQIFDVDGFELAAHRVIGLLRDVVGEFG 243 Query: 227 ----FSMHLLDIGGGF----------PGSEDTKLKFEEITSVINPALDKYFPSDSGVRII 272 + +D+GGG P + K I S + A+ P +++ Sbjct: 244 PEKTAQIATVDLGGGLGISYLPSDDPPPIAELAAKLGTIVSDESTAVGLPTP-----KLV 298 Query: 273 AEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYD 332 EPGR +A T+ T+++ D + + V+ G+ + LY Sbjct: 299 VEPGR-AIAGPGTI--------TLYEVGTVKDVDVSATAHRRYVSVDGGMSDNIRTALYG 349 Query: 333 HAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLP-EMHVGDWMLFENMGAYTV 391 + L+ + D + + G C+ D IV +P ++ GD + GAY Sbjct: 350 AQYDVRLVSR--VSDAPPVPARLVGKHCESGDIIVRDTWVPDDIRPGDLVAVAATGAYCY 407 Query: 392 AAASTFNGFQRPNIYYV 408 + +S +N RP + V Sbjct: 408 SLSSRYNMVGRPAVVAV 424 >3MT1-A nrPDB Length = 365 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 39/152 (25%), Positives = 58/152 (38%), Gaps = 35/152 (23%) Query: 261 KYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVND 320 + F GV+I EPG + + TL V ++ D Sbjct: 217 RAFSDRYGVQIYLEPGEASITKSTTLEVTVL----------------------------D 248 Query: 321 GVYGSFNCILYD---HAHVKALLQKRPK----PDEKYYSSSIWGPTCDGLDRIVERCNLP 373 +Y N + D AH+ LL R P+E +S I G +C D E Sbjct: 249 TLYNGKNLAIVDSSIEAHMLDLLIYRETAKVLPNEGSHSYMICGKSCLAGDVFGEFRFAE 308 Query: 374 EMHVGDWMLFENMGAYTVAAASTFNGFQRPNI 405 E+ VGD + F++ YT+ + FNG + P I Sbjct: 309 ELKVGDRISFQDAAGYTMVKKNWFNGVKMPAI 340 >3N29-A nrPDB Length = 418 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 68/298 (22%), Positives = 126/298 (42%), Gaps = 32/298 (10%) Query: 131 MTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKEL-NI 189 + F+S + K K L LR + S A L G + SRL + RAK+ N+ Sbjct: 136 IVFNSLAQFHKFQSKTQKNSLGLRCNVEFSLAPKELYNPCG---RYSRLGI-RAKDFENV 191 Query: 190 DVIGV-SFHVGSGCTDPETFVQAVSDARCVFD--MATEVGFSMHLLDIGGGFPGSEDTKL 246 D+ + H + C + ++AV VF+ +G M ++ GGG ++ Sbjct: 192 DLNAIEGLHFHALCEESADALEAVLK---VFEEKFGKWIG-QMKWVNFGGGHHITK---- 243 Query: 247 KFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDE 306 K ++ +I AL K F GV++ EPG L +++ K+ D Sbjct: 244 KGYDVEKLI--ALCKNFSDKYGVQVYLEPGEAVGWQTGNLVASVVDIIENEKQIAILDTS 301 Query: 307 DESN--EQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPD--EKYYSSSIWGPTCDG 362 E++ + M Y ++ + +A + A + D E ++ + G TC Sbjct: 302 SEAHMPDTIIMPYTSEVL----------NARILATRENEKISDLKENEFAYLLTGNTCLA 351 Query: 363 LDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 D + E ++ +GD ++F + YT+ +TFNG + PN+ + + Q++++ Sbjct: 352 GDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGIRLPNLMLLDHKNELQMIREF 409 >3N2O-A nrPDB Length = 648 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 62/276 (22%), Positives = 102/276 (36%), Gaps = 35/276 (12%) Query: 66 YAVKCNDSRAIVSTLAAIGT-------GFDCASKTEIQLVQGLGVPAERVIYANPCKQVS 118 Y +K N R +V + A G + SK E+ V + A VI N K Sbjct: 102 YPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDRE 161 Query: 119 QIKYAASNGV----------QMMTFDSEIELMKVARAHPKAKLVLRIATDDS---KAVCR 165 I+ A +M D + K P+ + +R+A+ + +A Sbjct: 162 YIRLALIGEKLGHKVFIVLEKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGG 221 Query: 166 LSVKFGATLKTSRLLLERAKELN-IDVIG-VSFHVGSGCTDPETFVQAVSDARCVFDMAT 223 KFG + ++ R K+ N +D + V FH+GS + V+++ + Sbjct: 222 EKSKFGLSASQVLNVISRLKKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELR 281 Query: 224 EVGFSMHLLDIGGGFPGSEDTKLK----------FEEITSVINPALD--KYFPSDSGVRI 271 +G ++ D+GGG D E +++N D K + V I Sbjct: 282 TLGANITYFDVGGGLAIDYDGTRSQSSNSMNYGLVEYARNIVNTVGDVCKDYKQPMPV-I 340 Query: 272 IAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDED 307 I+E GR A L N+I +T E +ED Sbjct: 341 ISESGRSLTAHHAVLISNVIGTETYKPETVTEPEED 376 >3NZQ-A nrPDB Length = 666 Score = 35.0 bits (79), Expect = 0.072, Method: Compositional matrix adjust. Identities = 56/259 (21%), Positives = 96/259 (37%), Gaps = 36/259 (13%) Query: 66 YAVKCNDSRAIVSTLAAIGT--GFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYA 123 Y +K N R ++ +L G G + SK E+ V VI N K I+ A Sbjct: 124 YPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLA 183 Query: 124 ASNGVQM---------------MTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSV 168 G +M + D L V R +A+L + + ++ Sbjct: 184 LI-GEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQ-GSGKWQSSGGEKS 241 Query: 169 KFGATLKTSRLLLERAKELN-IDVIGV-SFHVGSGCTDPETFVQAVSDARCVFDMATEVG 226 KFG L+E +E +D + + FH+GS + V ++ + ++G Sbjct: 242 KFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLG 301 Query: 227 FSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPS----------DSGV---RIIA 273 ++ D+GGG D + + +N L++Y + ++G+ +I Sbjct: 302 VNIQCFDVGGGL--GVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEENGLPHPTVIT 359 Query: 274 EPGRYYVASAFTLAVNIIA 292 E GR A L NII Sbjct: 360 ESGRAVTAHHTVLVSNIIG 378 >1VPB-A nrPDB Length = 451 Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust. Identities = 39/190 (20%), Positives = 74/190 (38%), Gaps = 31/190 (16%) Query: 222 ATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALD--KYFPSDSGVRIIAEPGRYY 279 A+E G S+ L + G + +L +E+ + I +D +Y D R++A+P RYY Sbjct: 62 ASEGGLSLSLY-VDGRYGSISTNRLNRKELETFIKNGIDSTRYLAKDE-ARVLADPSRYY 119 Query: 280 VASAFTLAV------------NIIAKKTVWKEQPGSDDE------DESNEQTFMY-YVND 320 L + I K V +E G D+ + + F Y +++ Sbjct: 120 KGGKPDLKLYDAKFASLNPDDKIEMAKAVAEEALGKDERIISVGSSYGDGEDFAYRLISN 179 Query: 321 GVYGSFNCILYD-HAHVKALLQKRPKPDEKYYSSSIW-------GPTCDGLDRIVERCNL 372 G G Y A + + +P +Y SS++ G L+R++ + Sbjct: 180 GFEGETKSTWYSLSADITIRGEGEARPSAYWYESSLYMNDLIKKGIGQKALERVLRKLGQ 239 Query: 373 PEMHVGDWML 382 ++ G + + Sbjct: 240 KKVQSGKYTM 249 >4G5E-A nrPDB Length = 517 Score = 31.6 bits (70), Expect = 0.74, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 68 VKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYA 111 ++ ND +VS + AIGTG A I + G+P +++I+A Sbjct: 176 IEKNDKGIVVSGVKAIGTGVAFADWIHIGVFFRPGIPGDQIIFA 219 >3CNO-A nrPDB Length = 262 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 9/109 (8%) Query: 245 KLKFEEITSV-INPALDK---YFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 KLK + +SV P + K +F ++GV+I+ PG Y + ++ AK + Sbjct: 118 KLKGKRASSVGAQPGITKGIQWFSLENGVKILDTPGILYKN---IFSEDLAAKLLLVGSL 174 Query: 301 PGSDDEDES-NEQTFMYYVND-GVYGSFNCILYDHAHVKALLQKRPKPD 347 P ED+ E+ F + G+ SF+ D A + LL+K PD Sbjct: 175 PVERIEDQRIFERAFEIFARSIGIESSFSEFFEDFARKRGLLKKGGVPD 223 >3HWC-A nrPDB Length = 515 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 23/44 (52%) Query: 68 VKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYA 111 V+ D IV+ + A+GTG I + G+P E+VI+A Sbjct: 175 VEKTDDGIIVNGVKAVGTGIAFGDYMHIGCLYRPGIPGEQVIFA 218 >5V5P-C nrPDB Length = 528 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 26/51 (50%) Query: 277 RYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFN 327 R+ S + ++N+I K +E+ + E+ + F + V DG G+FN Sbjct: 477 RHENESVYKASLNLIEKYFSVEEEEDQNVVPETTSEGFAFQVQDGAPGTFN 527 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 7ODC-A nrPDB 630 0.0 1D7K-A nrPDB 624 e-179 1NJJ-A nrPDB 555 e-158 4ZGZ-A nrPDB 481 e-136 4AIB-A nrPDB 396 e-110 2NV9-A nrPDB 381 e-106 2P3E-A nrPDB 364 e-101 5GJN-A nrPDB 362 e-100 2QGH-A nrPDB 356 1e-98 3N2B-A nrPDB 354 7e-98 2PLJ-A nrPDB 340 9e-94 4XG1-A nrPDB 327 5e-90 2YXX-A nrPDB 322 2e-88 1TWI-A nrPDB 317 8e-87 3VAB-A nrPDB 314 5e-86 1HKV-A nrPDB 305 4e-83 5X7M-A nrPDB 300 1e-81 2J66-A nrPDB 290 1e-78 1KNW-A nrPDB 253 1e-67 3MT1-A nrPDB 130 1e-30 Sequences not found previously or not previously below threshold: 3NZP-A nrPDB 92 4e-19 3N2O-A nrPDB 91 9e-19 3NZQ-A nrPDB 89 4e-18 3N29-A nrPDB 87 1e-17 3KS6-A nrPDB 36 0.035 6NXI-A nrPDB 33 0.37 5LDA-A nrPDB 32 0.55 4AWE-A nrPDB 32 0.64 4DEF-A nrPDB 31 0.93 2X0S-A nrPDB 31 1.2 5BSW-A nrPDB 31 1.3 2IX4-A nrPDB 30 2.4 5X5Y-G nrPDB 29 4.3 2C2L-A nrPDB 29 4.4 5TOO-A nrPDB 29 4.7 3AQ1-B nrPDB 29 6.2 3K5T-A nrPDB 29 7.0 5MRC-1 nrPDB 28 7.4 1Q7Q-A nrPDB 28 7.9 >7ODC-A nrPDB Length = 424 Score = 630 bits (1625), Expect = 0.0, Method: Composition-based stats. Identities = 423/424 (99%), Positives = 424/424 (100%) Query: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP Sbjct: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 Query: 61 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI 120 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI Sbjct: 61 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI 120 Query: 121 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL 180 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL Sbjct: 121 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL 180 Query: 181 LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG 240 LERAKELNIDVIGVSFHVGSGCTDP+TFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG Sbjct: 181 LERAKELNIDVIGVSFHVGSGCTDPDTFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG 240 Query: 241 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ Sbjct: 241 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 Query: 301 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC 360 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC Sbjct: 301 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC 360 Query: 361 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI Sbjct: 361 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 Query: 421 QSHG 424 QSHG Sbjct: 421 QSHG 424 >1D7K-A nrPDB Length = 421 Score = 624 bits (1608), Expect = e-179, Method: Composition-based stats. Identities = 388/421 (92%), Positives = 402/421 (95%) Query: 7 DEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFY 66 +EFDCH LDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFY Sbjct: 1 EEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFY 60 Query: 67 AVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASN 126 AVKCNDS+AIV TLAA GTGFDCASKTEIQLVQ LGVP ER+IYANPCKQVSQIKYAA+N Sbjct: 61 AVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANN 120 Query: 127 GVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKE 186 GVQMMTFDSE+ELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATL+TSRLLLERAKE Sbjct: 121 GVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKE 180 Query: 187 LNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKL 246 LNIDV+GVSFHVGSGCTDPETFVQA+SDARCVFDM EVGFSM+LLDIGGGFPGSED KL Sbjct: 181 LNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKL 240 Query: 247 KFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDE 306 KFEEIT VINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKK V KEQ GSDDE Sbjct: 241 KFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDE 300 Query: 307 DESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRI 366 DES+EQTFMYYVNDGVYGSFNCILYDHAHVK LLQKRPKPDE+YYSSSIWGPTCDGLDRI Sbjct: 301 DESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDERYYSSSIWGPTCDGLDRI 360 Query: 367 VERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFP 426 VERC+LPEMHVGDWMLFENMGAYTVAAASTFNGFQRP IYYVMS P WQLM+Q Q+ FP Sbjct: 361 VERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFP 420 Query: 427 P 427 P Sbjct: 421 P 421 >1NJJ-A nrPDB Length = 425 Score = 555 bits (1430), Expect = e-158, Method: Composition-based stats. Identities = 270/423 (63%), Positives = 328/423 (77%), Gaps = 2/423 (0%) Query: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 M D+ C L EGF +D L +KI+ +++ D+ D F+VADLGDI++KH W K LP Sbjct: 3 MDIVVNDDLSCRFL-EGFNTRDALCKKIS-MNTCDEGDPFFVADLGDIVRKHETWKKCLP 60 Query: 61 RVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQI 120 RVTPFYAVKCND ++ TLAA+GTGFDCAS TEIQ V+G+GVP E++IYANPCKQ+S I Sbjct: 61 RVTPFYAVKCNDDWRVLGTLAALGTGFDCASNTEIQRVRGIGVPPEKIIYANPCKQISHI 120 Query: 121 KYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL 180 +YA +GV +MTFD EL KVA+ HPKAK+VLRI+TDDS A CRLSVKFGA ++ R + Sbjct: 121 RYARDSGVDVMTFDCVDELEKVAKTHPKAKMVLRISTDDSLARCRLSVKFGAKVEDCRFI 180 Query: 181 LERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPG 240 LE+AK+LNIDV GVSFHVGSG TD TF QA+SD+R VFDM TE+GF+MH+LDIGGGFPG Sbjct: 181 LEQAKKLNIDVTGVSFHVGSGSTDASTFAQAISDSRFVFDMGTELGFNMHILDIGGGFPG 240 Query: 241 SEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ 300 + D LKFEEI VIN AL+K+FP D + I+AEPGRYYVASAFTLAVN+IAKK Q Sbjct: 241 TRDAPLKFEEIAGVINNALEKHFPPDLKLTIVAEPGRYYVASAFTLAVNVIAKKVTPGVQ 300 Query: 301 PGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTC 360 ESN Q+FMYYVNDGVYGSFNCILYDHA V+ L Q+ P P+EK Y SS+WGPTC Sbjct: 301 TDVGAHAESNAQSFMYYVNDGVYGSFNCILYDHAVVRPLPQREPIPNEKLYPSSVWGPTC 360 Query: 361 DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQI 420 DGLD+IVER LPEM VG+W+LFE+MGAYTV S+FNGFQ P IYYV+S +++++ Sbjct: 361 DGLDQIVERYYLPEMQVGEWLLFEDMGAYTVVGTSSFNGFQSPTIYYVVSGLPDHVVREL 420 Query: 421 QSH 423 +S Sbjct: 421 KSQ 423 >4ZGZ-A nrPDB Length = 438 Score = 481 bits (1238), Expect = e-136, Method: Composition-based stats. Identities = 222/417 (53%), Positives = 296/417 (70%), Gaps = 6/417 (1%) Query: 4 FTKD-EFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRV 62 F D + +LDEG +++D + E + + K+AF+V DLG I+KKH +W + ++ Sbjct: 5 FIDDANYSVGLLDEGTDLGNVIDNYVYEHTLTG-KNAFFVGDLGKIVKKHSQWQNVVAQI 63 Query: 63 TPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKY 122 PFY VKCN + A++ LAA+GTGF C+SK E+ LVQ LGVP E +IY +PCKQVSQIKY Sbjct: 64 KPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKY 123 Query: 123 AASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLE 182 AA GV ++T D+EIEL K+AR HP AK++L IAT+D+ ++KFG TLK R LLE Sbjct: 124 AAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKNCRHLLE 183 Query: 183 RAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSE 242 AKEL++ +IGV FHV S C + + +V A+SDARCVFDMA E+GF+M++LDIGGGF G+E Sbjct: 184 CAKELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIGFTMNMLDIGGGFTGTE 243 Query: 243 DTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQ-P 301 + EE+ VI+P LD YFP SGV+II+EPG YYV+SAFTLAVNIIAKK V ++ P Sbjct: 244 ---FQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFP 300 Query: 302 GSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCD 361 ++ S+E FMYY+NDGVYGSF L + + + K+ K DE ++SS+WGP+CD Sbjct: 301 SGVEKTGSDEPAFMYYMNDGVYGSFASKLSEDLNTIPEVHKKYKEDEPLFTSSLWGPSCD 360 Query: 362 GLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMK 418 LD+IVE C LPE++VGDW++F+NMGA + S FN FQRP IYY+MS W M+ Sbjct: 361 ELDQIVESCLLPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQ 417 >4AIB-A nrPDB Length = 395 Score = 396 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 129/391 (32%), Positives = 205/391 (52%), Gaps = 21/391 (5%) Query: 26 QKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGT 85 I++ + F++ D + K RW K +P V P +AVKCN +V L +G Sbjct: 14 NLISQFEPENQPLGFWIFDTEGVEKAVERWKKNMPTVRPCFAVKCNPEPHLVKLLGELGC 73 Query: 86 GFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARA 145 GFDCAS EI+ V LG E + Y+ K +Q+ A+ G+ DS E+ K+A+ Sbjct: 74 GFDCASLNEIKEVLDLGFNPEDITYSQTFKPYNQLIEASHLGINHTIVDSIDEVQKIAKY 133 Query: 146 HPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDP 205 PK +++RI +D+ A KFG ++L+ K+ +++ GV FHVGS + Sbjct: 134 APKMGIMIRIMENDTSAGHVFGEKFGLHDDEVEIVLKEIKDKGLNLDGVHFHVGSDSHNS 193 Query: 206 ETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKY-FP 264 E F +A++ AR +A + G +L+DIGGGF FEE + I + + FP Sbjct: 194 EVFTKALTKARNTVTLAEQFGMKPYLIDIGGGF----SQVAPFEEFAATIEKTIKELEFP 249 Query: 265 SDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYG 324 + R IAEPGRY ++AF L ++ K+ ++ ++ Y DG++G Sbjct: 250 ERT--RFIAEPGRYMASNAFHLVSSLHGKRV----------RIQNGKKQIEYTSGDGLHG 297 Query: 325 SFN-CILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVG-DWML 382 SF CI ++ + ++ + K Y S I+GP+C+G D++ + LPEM G DW+L Sbjct: 298 SFGCCIWFEKQKSCECITQKVNENTKMYESIIYGPSCNGSDKVATQ-ELPEMEPGKDWLL 356 Query: 383 FENMGAYTVAAASTFNGFQRPNIYYVMSRPM 413 F NMGAYT++ A+ FNGF+ N + + + P+ Sbjct: 357 FPNMGAYTISMATNFNGFEERN-HVIYTLPL 386 >2NV9-A nrPDB Length = 372 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 138/373 (36%), Positives = 207/373 (55%), Gaps = 15/373 (4%) Query: 36 DKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEI 95 +FYV+ + +W PRVTP YAVKCN+ ++ T+ FDCAS +EI Sbjct: 15 QTKSFYVSSPKIVEDLIDQWTILFPRVTPHYAVKCNNDEVLLKTMCDKNVNFDCASSSEI 74 Query: 96 QLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRI 155 + V +GV R+I+A+ K + + +A GV + TFDS EL K+ HP K++LRI Sbjct: 75 KKVIQIGVSPSRIIFAHTMKTIDDLIFAKDQGVDIATFDSSFELDKIHTYHPNCKMILRI 134 Query: 156 ATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDA 215 DD A +L KFGA R LLE AK+L+I+VIG+SFHVGSG +PE + +A+ + Sbjct: 135 RCDDPNAAVQLGNKFGANEDEIRHLLEYAKQLDIEVIGISFHVGSGSRNPEAYYRAIKSS 194 Query: 216 RCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEP 275 + F+ A VG ++LDIGGG D ++ IN A+ +FP D+ V I+AEP Sbjct: 195 KEAFNEAISVGHKPYILDIGGGLHADIDEGELSTYMSDYINDAIKDFFPEDT-VTIVAEP 253 Query: 276 GRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAH 335 GR++ LA +I K+ + + Y+ N+ YG F+ ++++ + Sbjct: 254 GRFFAEHYSVLATQVIGKRV--------------RDGLYEYFFNESTYGGFSNVIFEKSV 299 Query: 336 VKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAAS 395 L + DE+Y S ++G TCDG+D I LPE+H+GDW+ F + GAYT + Sbjct: 300 PTPQLLRDVPDDEEYVPSVLYGCTCDGVDVINHNVALPELHIGDWVYFPSWGAYTNVLTT 359 Query: 396 TFNGFQRPNIYYV 408 +FNGF ++YY+ Sbjct: 360 SFNGFGEYDVYYI 372 >2P3E-A nrPDB Length = 420 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 94/394 (23%), Positives = 166/394 (42%), Gaps = 30/394 (7%) Query: 37 KDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQ 96 YV I ++ + KA P YAVK N + +V L +G G D S E+ Sbjct: 33 GTPLYVYSSNFIKERFEAYRKAFPDALICYAVKANFNPHLVKLLGELGAGADIVSGGELY 92 Query: 97 LVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHP----KAKLV 152 L + G+P ER++YA K ++ A + + M +S EL + KA++ Sbjct: 93 LAKKAGIPPERIVYAGVGKTEKELTDAVDSEILMFNVESRQELDVLNEIAGKLGKKARIA 152 Query: 153 LRIATD-DSKAVCRLSV-----KFGATLKTSRLLLERAKEL-NIDVIGVSFHVGSGCTDP 205 +R+ D D K ++ KFG ++ ++ E A +L N++++G+ H+GS D Sbjct: 153 IRVNPDVDPKTHPYIATGMQKSKFGVDIREAQKEYEYASKLENLEIVGIHCHIGSQILDI 212 Query: 206 ETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPS 265 + +AV +++ T+ GF + LDIGGG K + +E L K Sbjct: 213 SPYREAVEKVVSLYESLTQKGFDIKYLDIGGGLGIKY--KPEDKEPAPQDLADLLKDLLE 270 Query: 266 DSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGS 325 + +II EPGR + +A L + K + V+ G+ Sbjct: 271 NVKAKIILEPGRSIMGNAGILITQVQFLKDKGSKH--------------FIIVDAGMNDL 316 Query: 326 FNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFEN 385 +Y+ H ++ + + K + I GP C+ D + + E+ G+++ + Sbjct: 317 IRPSIYNAYHHIIPVETK---ERKKVVADIVGPICETGDFLALDREIEEVQRGEYLAVLS 373 Query: 386 MGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQ 419 GAY A +S +N R V + + + K+ Sbjct: 374 AGAYGFAMSSHYNMRPRAAEVLVENGSVKLIRKR 407 >5GJN-A nrPDB Length = 393 Score = 362 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 128/366 (34%), Positives = 200/366 (54%), Gaps = 23/366 (6%) Query: 37 KDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQ 96 F VA L + + + + LPR FYA+K N + I+S LA +G+ FD AS E++ Sbjct: 19 PTPFLVASLDKVEENYQFMRRHLPRAGVFYAMKANPTPEILSLLAGLGSHFDVASAGEME 78 Query: 97 LVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIA 156 ++ LGV ++IYANP K +K AA V+ TFD E+ K+A+A P A +++RIA Sbjct: 79 ILHELGVDGSQMIYANPVKDARGLKAAADYNVRRFTFDDPSEIDKMAKAVPGADVLVRIA 138 Query: 157 TDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDAR 216 ++KA+ L+ KFGA ++ + LL+ A++ + +G+ FHVGS + +A+ AR Sbjct: 139 VRNNKALVDLNTKFGAPVEEALDLLKAAQDAGLHAMGICFHVGSQSLSTAAYEEALLVAR 198 Query: 217 CVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFE--EITSVINPALDKYFPSDSGVRIIAE 274 +FD A E+G + LDIGGGFP + L + + IN +D+ FP + + E Sbjct: 199 RLFDEAEEMGMHLTDLDIGGGFPVPDAKGLNVDLAAMMEAINKQIDRLFPDTA---VWTE 255 Query: 275 PGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHA 334 PGRY +A L ++I KT ++ Y +++G+YG F+ I+YD Sbjct: 256 PGRYMCGTAVNLVTSVIGTKTRGEQP--------------WYILDEGIYGCFSGIMYD-- 299 Query: 335 HVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAA 394 H L K ++K S+ GP+CDG+D + PE+ +GD +L MG+YT +A Sbjct: 300 HWTYPLHCFGKGNKK--PSTFGGPSCDGIDVLYRDFMAPELKIGDKVLVTEMGSYTSVSA 357 Query: 395 STFNGF 400 + FNGF Sbjct: 358 TRFNGF 363 >2QGH-A nrPDB Length = 425 Score = 356 bits (914), Expect = 1e-98, Method: Composition-based stats. Identities = 94/388 (24%), Positives = 162/388 (41%), Gaps = 40/388 (10%) Query: 37 KDAFYVADLGDILKKHLRWLKALPRVT--PFYAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 K FY+ D I + L + +A YA+K N + +I+S LA + +G DC S E Sbjct: 32 KTPFYLYDFDKIKQAFLNYKEAFKGRKSLICYALKANSNLSILSLLAHLESGADCVSIGE 91 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHP----KAK 150 IQ G+ R++++ K +I+ A + + +S +EL + KA+ Sbjct: 92 IQRALKAGIKPYRIVFSGVGKSAFEIEQALKLNILFLNVESFMELKTIETIAQSLGIKAR 151 Query: 151 LVLRIATD-DSKAVCRLSV-----KFGATLKTS-RLLLERAKELNIDVIGVSFHVGSGCT 203 + +RI + D+K +S KFG K + + L K ++ + V FH+GS Sbjct: 152 ISIRINPNIDAKTHPYISTGLKENKFGVGEKEALEMFLWAKKSAFLEPVSVHFHIGSQLL 211 Query: 204 DPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGS---EDTKLKFEEITSVINPALD 260 D E ++A + +G + D+GGG S E+T ++ ++N Sbjct: 212 DLEPIIEASQKVAKIAKSLIALGIDLRFFDVGGGIGVSYENEETIKLYDYAQGILNAL-- 269 Query: 261 KYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVND 320 + II EPGR VA + L ++ +K + V+ Sbjct: 270 ----QGLDLTIICEPGRSIVAESGELITQVLYEKKAQNK--------------RFVIVDA 311 Query: 321 GVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDW 380 G+ LY H ++ P + + GP C+ D ++ +LPE+ GD Sbjct: 312 GMNDFLRPSLYHAKHAIRVIT--PSKGREISPCDVVGPVCESSDTFLKDAHLPELEPGDK 369 Query: 381 MLFENMGAYTVAAASTFNGFQRPNIYYV 408 + E +GAY + AS +N RP + + Sbjct: 370 IAIEKVGAYGSSMASQYN--SRPKLLEL 395 >3N2B-A nrPDB Length = 441 Score = 354 bits (907), Expect = 7e-98, Method: Composition-based stats. Identities = 103/433 (23%), Positives = 171/433 (39%), Gaps = 46/433 (10%) Query: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 M F E D + E D+ +Q YV + + + K++ Sbjct: 25 MDYFNYQE-DGQLWAEQVPLADLANQY---------GTPLYVYSRATLERHWHAFDKSVG 74 Query: 61 RV--TPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVS 118 YAVK N + +++TLA +G+GFD S E++ V G +V+++ K + Sbjct: 75 DYPHLICYAVKANSNLGVLNTLARLGSGFDIVSVGELERVLAAGGDPSKVVFSGVGKTEA 134 Query: 119 QIKYAASNGVQMMTFDSEIELMKVARAHP----KAKLVLRIATD-DSKAVCRLSV----- 168 ++K A ++ +SE EL ++ + KA + LRI D D+K +S Sbjct: 135 EMKRALQLKIKCFNVESEPELQRLNKVAGELGVKAPISLRINPDVDAKTHPYISTGLRDN 194 Query: 169 KFGATLKTSRLLLERAKEL-NIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGF 227 KFG T + + A L N+DV G+ H+GS T F+ A + D G Sbjct: 195 KFGITFDRAAQVYRLAHSLPNLDVHGIDCHIGSQLTALAPFIDATDRLLALIDSLKAEGI 254 Query: 228 SMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLA 287 + LD+GGG +L + S AL + +I EPGR A+A L Sbjct: 255 HIRHLDVGGGLGVVYRDELPPQ--PSEYAKALLDRLERHRDLELIFEPGRAIAANAGVLV 312 Query: 288 VNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPD 347 + K E ++ + LY + ++ RP+ Sbjct: 313 TKVEFLKHT--------------EHKNFAIIDAAMNDLIRPALYQAW--QDIIPLRPRQG 356 Query: 348 EKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYY 407 E + + GP C+ D + + +L + GD + + GAY +S +N RP + Sbjct: 357 EA-QTYDLVGPVCETSDFLGKDRDLV-LQEGDLLAVRSSGAYGFTMSSNYN--TRPRVAE 412 Query: 408 VM-SRPMWQLMKQ 419 VM L++Q Sbjct: 413 VMVDGNKTYLVRQ 425 >2PLJ-A nrPDB Length = 419 Score = 340 bits (871), Expect = 9e-94, Method: Composition-based stats. Identities = 124/375 (33%), Positives = 195/375 (52%), Gaps = 22/375 (5%) Query: 30 EVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDC 89 E S + D I +++ ALP VT YA+K +V TL A G FD Sbjct: 47 EASVEQFGAPLLLLDCDVIRQQYRALKNALPNVTLHYALKPLPHPVVVRTLLAEGASFDL 106 Query: 90 ASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKA 149 A+ E++LV GVPA+ I+ +P K+ + I+ A + G + D+ EL K Sbjct: 107 ATTGEVELVASEGVPADLTIHTHPIKRDADIRDALAYGCNVFVVDNLNELEKFKAYRDDV 166 Query: 150 KLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFV 209 +L++R++ +S+A LS KFG + + + +++E AKE NI + G+SFHVGS T+P +V Sbjct: 167 ELLVRLSFRNSEAFADLSKKFGCSPEQALVIIETAKEWNIRIKGLSFHVGSQTTNPNKYV 226 Query: 210 QAVSDARCVFDMATEVGF-SMHLLDIGGGFPGSEDTK-LKFEEITSVINPALDKYFPSDS 267 +A+ R V + E G ++ LDIGGGFP + + + ++ + IN AL Sbjct: 227 EAIHTCRHVMEQVVERGLPALSTLDIGGGFPVNYTQQVMPIDQFCAPINEALSLL---PE 283 Query: 268 GVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFN 327 V ++AEPGR+ A A T +++ + E YY++DG+YGSF+ Sbjct: 284 TVHVLAEPGRFICAPAVTSVASVMGQA--------------EREGQIWYYLDDGIYGSFS 329 Query: 328 CILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMG 387 +++D A K+ + S + GPTCD +D I E LP+++ GD ++ MG Sbjct: 330 GLMFDDARYPLTTIKQ---GGELIPSVLSGPTCDSVDVIAENILLPKLNNGDLVIGRTMG 386 Query: 388 AYTVAAASTFNGFQR 402 AYT A A+ FN F+R Sbjct: 387 AYTSATATDFNFFKR 401 >4XG1-A nrPDB Length = 427 Score = 327 bits (839), Expect = 5e-90, Method: Composition-based stats. Identities = 91/423 (21%), Positives = 171/423 (40%), Gaps = 51/423 (12%) Query: 1 MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALP 60 M F + D + EG + ++ + Y+ +++H + + Sbjct: 1 MDHF-NYQNDGRLFVEGLPVEQVVKK---------TGTPAYIYSRA-TIERHWQAFDSAA 49 Query: 61 RVTP---FYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQV 117 P YAVK N + A+++ +A +G+GFD S E+ V G ++++++ K Sbjct: 50 GKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTE 109 Query: 118 SQIKYAASNGVQMMTFDSEIELMKVA----RAHPKAKLVLRIATD-DSKAVCRLSV---- 168 +I A + +S EL ++ + KA + +RI + D+ +S Sbjct: 110 IEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKE 169 Query: 169 -KFGATLKTSRLLLERAKELN-IDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVG 226 KFG ++ + + + A +L +++ GV H+GS T+ F++A+ + D+ E G Sbjct: 170 NKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKG 229 Query: 227 FSMHLLDIGGGFPGSEDT---KLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASA 283 ++ LD+GGG D E +T++IN + +++I EPGR +A+A Sbjct: 230 ITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGR------SLKLIFEPGRAIMANA 283 Query: 284 FTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKR 343 L + K N+ V+ + LY L Sbjct: 284 GVLVTKVEFLKL--------------NDYKNFAIVDAAMNDLIRPALYSAWQNIIPLNTD 329 Query: 344 PKP--DEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQ 401 + D S I GP C+ D + + L + GD+++ + GAY +S +N Sbjct: 330 YQDGQDRPVRSYDIVGPICETGDFLGKERQL-ALAEGDYLVIRSTGAYGSTMSSNYNSRC 388 Query: 402 RPN 404 R Sbjct: 389 RAA 391 >2YXX-A nrPDB Length = 386 Score = 322 bits (824), Expect = 2e-88, Method: Composition-based stats. Identities = 98/398 (24%), Positives = 168/398 (42%), Gaps = 43/398 (10%) Query: 37 KDAFYVADLGDILKKHLRWLKAL---PRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKT 93 YV + L+K R +K + + P +AVK N++ ++ L G G D +K Sbjct: 12 GTPTYVY-FEETLRKRSRLVKEVFEGVNLLPTFAVKANNNPVLLKILREEGFGMDVVTKG 70 Query: 94 EIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKA-KLV 152 E+ + GVP+ V++ K Q+++ V+++ DS E+ +P+ + Sbjct: 71 ELLAAKLAGVPSHTVVWNGNGKSRDQMEHFLREDVRIVNVDSFEEMEIWRELNPEGVEYF 130 Query: 153 LRIATD-DSKAVCRLSV-----KFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPE 206 +R+ + D+K +S KFG L+ +ER + +NI G+ H+GS T E Sbjct: 131 IRVNPEVDAKTHPHISTGLKKHKFGIPLEDLDSFMERFRSMNIR--GLHVHIGSQITRVE 188 Query: 207 TFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSED-TKLKFEEITSVINPALDKYFPS 265 FV+A S V + GF ++IGGG+ + +L + P L ++ Sbjct: 189 PFVEAFSK---VVRASERYGFE--EINIGGGWGINYSGEELDLSSYREKVVPDLKRFK-- 241 Query: 266 DSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGS 325 R+I E GRY VA + L + ++ K + V+ G+ Sbjct: 242 ----RVIVEIGRYIVAPSGYLLLRVVLVKRRHNKA--------------FVVVDGGMNVL 283 Query: 326 FNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFEN 385 LY H +L K+ K + + GP C+ D I LPE+ GD + EN Sbjct: 284 IRPALYSAYHRIFVLGKQGKE----MRADVVGPLCESGDVIAYDRELPEVEPGDIIAVEN 339 Query: 386 MGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSH 423 GAY ++ +N RP V L+++ ++ Sbjct: 340 AGAYGYTMSNNYNSTTRPAEVLVRENGRISLIRRRETE 377 >1TWI-A nrPDB Length = 434 Score = 317 bits (812), Expect = 8e-87, Method: Composition-based stats. Identities = 95/422 (22%), Positives = 173/422 (40%), Gaps = 53/422 (12%) Query: 10 DCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPR-------- 61 D +G+ A ++ ++ YV I + R+++A R Sbjct: 11 DGRFFIDGYDAIELAEKF---------GTPLYVMSEEQIKINYNRYIEAFKRWEEETGKE 61 Query: 62 VTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIK 121 YA K N + AI LA +G G D S E+ + + VP++++++ CK +I Sbjct: 62 FIVAYAYKANANLAITRLLAKLGCGADVVSGGELYIAKLSNVPSKKIVFNGNCKTKEEII 121 Query: 122 YAASNGVQMMTFDSEIELMKVARAHPK----AKLVLRIATD-DSKAVCRLSV-----KFG 171 ++ DS EL+ + + A + RI + + K ++S KFG Sbjct: 122 MGIEANIRAFNVDSISELILINETAKELGETANVAFRINPNVNPKTHPKISTGLKKNKFG 181 Query: 172 ATLKTSRLLLERAKELN---IDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFS 228 +++ + L ++V+GV H+GS TD F++ E G Sbjct: 182 LDVESGIAMKAIKMALEMEYVNVVGVHCHIGSQLTDISPFIEETRKVMDFVVELKEEGIE 241 Query: 229 MHLLDIGGGF--PGSEDTKLKFEE--ITSVINPALDKYFPSDSGVRIIAEPGRYYVASAF 284 + +++GGG P +D ++ ++ ++IN L KY +I EPGR VA+A Sbjct: 242 IEDVNLGGGLGIPYYKDKQIPTQKDLADAIINTML-KYKDKVEMPNLILEPGRSLVATAG 300 Query: 285 TLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRP 344 L + K KE P T ++ G+ +Y+ H ++ + Sbjct: 301 YL----LGKVHHIKETPV----------TKWVMIDAGMNDMMRPAMYEAYHH--IINCKV 344 Query: 345 KPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPN 404 K +++ S I G C+ D L ++ VGD + ++GAY ++ A+ +N RP Sbjct: 345 KNEKEVVS--IAGGLCESSDVFGRDRELDKVEVGDVLAIFDVGAYGISMANNYNARGRPR 402 Query: 405 IY 406 + Sbjct: 403 MV 404 >3VAB-A nrPDB Length = 443 Score = 314 bits (804), Expect = 5e-86, Method: Composition-based stats. Identities = 91/376 (24%), Positives = 151/376 (40%), Gaps = 29/376 (7%) Query: 37 KDAFYVADLGDILKKHLRWLKALPRV--TPFYAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 FYV I + + A + YA+K N ++A+++ LA +G G D S+ E Sbjct: 48 GTPFYVYSRATIERHFRVFHDAFADMDTLVTYALKANSNQAVLTALAKLGAGADTVSQGE 107 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVAR---AHPK-AK 150 I+ G+PA R++++ K ++ +A G+ +SE EL ++ A K A Sbjct: 108 IRRALAAGIPANRIVFSGVGKTPREMDFALEAGIYCFNVESEPELEILSARAVAAGKVAP 167 Query: 151 LVLRIATD-DSKAVCRLSV-----KFGATLKTSRLLLERAKEL-NIDVIGVSFHVGSGCT 203 + LRI D D+K ++S KFG +R RA L ++V+G+ H+GS Sbjct: 168 VSLRINPDVDAKTHAKISTGKSENKFGIPRDKARAAYARAASLPGLNVVGIDMHIGSQII 227 Query: 204 DPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYF 263 D E F A + + G ++ +D+GGG V + Sbjct: 228 DLEPFDNAFALMAELVKELQADGHNIRHVDVGGGLGIPY-RTPNTPPPPPVAYAQIVAKH 286 Query: 264 PSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVY 323 G++ + EPGR V +A L +I K E + + F V+ + Sbjct: 287 IKPLGLKTVFEPGRLIVGNAGLLVTEVIFVK-------------EGDAKNF-VIVDAAMN 332 Query: 324 GSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLF 383 LYD H + P + + GP C+ D + + + GD + Sbjct: 333 DLIRPTLYDAFHDIRPVIM-PNDNAPRIRADFVGPVCETGDYLGLDREVAKPAPGDLIAI 391 Query: 384 ENMGAYTVAAASTFNG 399 GAY +ST+N Sbjct: 392 CTTGAYGAVLSSTYNS 407 >1HKV-A nrPDB Length = 453 Score = 305 bits (780), Expect = 4e-83, Method: Composition-based stats. Identities = 81/418 (19%), Positives = 147/418 (35%), Gaps = 56/418 (13%) Query: 37 KDAFYVADLGDILKKHLRWLKAL-PRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEI 95 +V D D + A YA K + ++ G D + E+ Sbjct: 39 GTPLFVIDEDDFRSRCRETAAAFGSGANVHYAAKAFLCSEVARWISEEGLCLDVCTGGEL 98 Query: 96 QLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLV--- 152 + P ER+ K VS++ A GV + DS E+ ++ +A +V Sbjct: 99 AVALHASFPPERITLHGNNKSVSELTAAVKAGVGHIVVDSMTEIERLDAIAGEAGIVQDV 158 Query: 153 ---------------LRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFH 197 + A +D K LSV GA + R + ++ ++G+ H Sbjct: 159 LVRLTVGVEAHTHEFISTAHEDQK--FGLSVASGAAMAAVRRVFATD---HLRLVGLHSH 213 Query: 198 VGSGCTDPETFVQAVSDARCVF-DMATEVG----FSMHLLDIGGGF----------PGSE 242 +GS D + F A + D+ E G + +D+GGG P Sbjct: 214 IGSQIFDVDGFELAAHRVIGLLRDVVGEFGPEKTAQIATVDLGGGLGISYLPSDDPPPIA 273 Query: 243 DTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPG 302 + K I S + A+ P +++ EPGR T+++ Sbjct: 274 ELAAKLGTIVSDESTAVGLPTP-----KLVVEPGRAIAGP---------GTITLYEVGTV 319 Query: 303 SDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDG 362 D + + V+ G+ + LY + L+ + D + + G C+ Sbjct: 320 KDVDVSATAHRRYVSVDGGMSDNIRTALYGAQYDVRLVSR--VSDAPPVPARLVGKHCES 377 Query: 363 LDRIVERCNLP-EMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQ 419 D IV +P ++ GD + GAY + +S +N RP + V + ++++ Sbjct: 378 GDIIVRDTWVPDDIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVHAGNARLVLRR 435 >5X7M-A nrPDB Length = 453 Score = 300 bits (768), Expect = 1e-81, Method: Composition-based stats. Identities = 86/407 (21%), Positives = 157/407 (38%), Gaps = 32/407 (7%) Query: 34 SDDKDAFYVADLGDILKKHLRWLKALPRVT-PFYAVKCNDSRAIVSTLAAIGTGFDCASK 92 + +V D D + A YA K ++ I + G D AS Sbjct: 39 EEYGTPLFVVDEDDFRSRCRDMATAFGGPGNVHYASKAFLTKTIARWVDEEGLALDIASI 98 Query: 93 TEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIE---LMKVARAHPKA 149 E+ + G PA R+ K V ++ NGV + DS E L VA K Sbjct: 99 NELGIALAAGFPASRITAHGNNKGVEFLRALVQNGVGHVVLDSAQELELLDYVAAGEGKI 158 Query: 150 K-LVLRIAT------DDSKAVCRLSVKFGATLKTSR---LLLERAKELNIDVIGVSFHVG 199 + +++R+ + A KFG +L + N++++G+ HVG Sbjct: 159 QDVLIRVKPGIEAHTHEFIATSHEDQKFGFSLASGSAFEAAKAANNAENLNLVGLHCHVG 218 Query: 200 SGCTDPETFVQAVSDARCVFDM-ATEVGFSMHLLDIGGGFPGSE---DTKLKFEEITSVI 255 S D E F A ++ +E+G ++ LD+GGG+ + + L E+ S + Sbjct: 219 SQVFDAEGFKLAAERVLGLYSQIHSELGVALPELDLGGGYGIAYTAAEEPLNVAEVASDL 278 Query: 256 NPALDKYFPSD--SGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQT 313 A+ K ++ EPGR + T+++ D + ++ Sbjct: 279 LTAVGKMAAELGIDAPTVLVEPGRAIAGPSTV---------TIYEVGTTKDVHVDDDKTR 329 Query: 314 FMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLP 373 V+ G+ + LY + ++ + + D S+ I G C+ D ++ P Sbjct: 330 RYIAVDGGMSDNIRPALYGSEYDARVVSRFAEGDP--VSTRIVGSHCESGDILINDEIYP 387 Query: 374 -EMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQ 419 ++ GD++ GAY A +S +N F RP + V + ++++ Sbjct: 388 SDITSGDFLALAATGAYCYAMSSRYNAFTRPAVVSVRAGSSRLMLRR 434 >2J66-A nrPDB Length = 428 Score = 290 bits (741), Expect = 1e-78, Method: Composition-based stats. Identities = 80/386 (20%), Positives = 163/386 (42%), Gaps = 49/386 (12%) Query: 37 KDAFYVADLGDILKKHLRWLKAL--PRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 + FY+ D GD ++ H R L++ P + + ++K N++ + G G + AS E Sbjct: 16 ETPFYLYD-GDFIEAHYRQLRSRTNPAIQFYLSLKANNNIHLAKLFRQWGLGVEVASAGE 74 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPK----AK 150 + L + G AE +I++ P K+ S+++ A +G+ + +S EL + K A+ Sbjct: 75 LALARHAGFSAENIIFSGPGKKRSELEIAVQSGIYCIIAESVEELFYIEELAEKENKTAR 134 Query: 151 LVLRIATDDSKAVCRLSV-----KFGATLKTSRLLLERAKELNI-DVIGVSFHVGSGCTD 204 + +RI D S + + +FG +++ + L IG+ + G+ + Sbjct: 135 VAIRINPDKSFGSTAIKMGGVPRQFGMDESMLDAVMDAVRSLQFTKFIGIHVYTGTQNLN 194 Query: 205 PETFVQA----VSDARCVFDMATEVGFSMHLLDIGGGFPG---SEDTKLKFEEITSVINP 257 ++ +++ V R +++ G +++GGGF S + L +IT ++ Sbjct: 195 TDSIIESMKYTVDLGRNIYE---RYGIVCECINLGGGFGVPYFSHEKALDIGKITRTVSD 251 Query: 258 ----ALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQT 313 A D FP I E GRY +A A ++ +K E Sbjct: 252 YVQEARDTRFPQT---TFIIESGRYLLAQAAVYVTEVLYRKASKGE-------------- 294 Query: 314 FMYYVNDGVY----GSFNC-ILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVE 368 V+ G++ +F + + ++ + + + +I GP C D + + Sbjct: 295 VFVIVDGGMHHHAASTFRGRSMRSNYPMEYIPVREDSGRRELEKVTIAGPLCTPEDCLGK 354 Query: 369 RCNLPEMHVGDWMLFENMGAYTVAAA 394 ++P ++ GD + N GAY ++ + Sbjct: 355 DVHVPALYPGDLVCVLNSGAYGLSFS 380 >1KNW-A nrPDB Length = 425 Score = 253 bits (647), Expect = 1e-67, Method: Composition-based stats. Identities = 70/412 (16%), Positives = 143/412 (34%), Gaps = 49/412 (11%) Query: 33 SSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASK 92 ++ +V D I+++ + LK V +A K + I+ + G D S Sbjct: 21 PAEFGCPVWVYDA-QIIRRQIAALKQFDVVR--FAQKACSNIHILRLMREQGVKVDSVSL 77 Query: 93 TEIQLVQGLGVPA----ERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPK 148 EI+ G + +++ + ++ + + + S L ++ + P Sbjct: 78 GEIERALAAGYNPQTHPDDIVFTADVIDQATLERVSELQIP-VNAGSVDMLDQLGQVSPG 136 Query: 149 AKLVLRIATDDSKAVC------RLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGC 202 ++ LR+ + K G L+ + ++ ++G+ H+GSG Sbjct: 137 HRVWLRVNPGFGHGHSQKTNTGGENSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGV 196 Query: 203 TDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSE---DTKLKFEEITSVINPAL 259 + + E G + + GGG + + E + N A Sbjct: 197 D----YAHLEQVCGAMVRQVIEFGQDLQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAR 252 Query: 260 DKYFPS-DSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYV 318 ++ V++ EPGR+ VA + L + + K + V Sbjct: 253 EQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQMGSRH--------------FVLV 298 Query: 319 NDGVYGSFNCILYDHAHVKALL--QKRPKPDEKYYSSSIWGPTCDGLDRI-------VER 369 + G +Y H + L R + + GP C+ D VE Sbjct: 299 DAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVETVVAGPLCESGDVFTQQEGGNVET 358 Query: 370 CNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVM--SRPMWQLMKQ 419 LPE+ GD+++ + GAY + +S +N RP + V+ + + ++ Sbjct: 359 RALPEVKAGDYLVLHDTGAYGASMSSNYN--SRPLLPEVLFDNGQARLIRRR 408 >3MT1-A nrPDB Length = 365 Score = 130 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 75/389 (19%), Positives = 134/389 (34%), Gaps = 69/389 (17%) Query: 37 KDAFYVADLGDILKKHLR--WLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 + +Y+ D + + R ++ A+KC + ++ + G +S E Sbjct: 3 ETPYYLIDKAKLTRNMERIAHVREKSGAKALLALKCFATWSVFDLMRDYMDGTTSSSLFE 62 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLR 154 ++L + E Y+ ++I S+ + F+S +L + A LR Sbjct: 63 VRLGRER-FGKETHAYS-VAYGDNEIDEVVSHA-DKIIFNSISQLERFADKAAGIARGLR 119 Query: 155 IATDDSKAVCRLS------VKFG-ATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPET 207 + S + L+ + G + +++R G H D Sbjct: 120 LNPQVSSSSFDLADPARPFSRLGEWDVPKVERVMDRIN-------GFMIHNNCENKDFGL 172 Query: 208 FVQAVSDARCVFDMATEVGFSMHLLD---IGGGFPGSEDTKLKFEEITSVINPALDKYFP 264 F R + ++ G + +D +GGG + D + A + F Sbjct: 173 FD------RMLGEIEERFGALIARVDWVSLGGGIHFTGD------DYPVDAFSARLRAFS 220 Query: 265 SDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYG 324 GV+I EPG + + TL V ++ D +Y Sbjct: 221 DRYGVQIYLEPGEASITKSTTLEVTVL----------------------------DTLYN 252 Query: 325 SFNCILYD---HAHVKALLQKRPK----PDEKYYSSSIWGPTCDGLDRIVERCNLPEMHV 377 N + D AH+ LL R P+E +S I G +C D E E+ V Sbjct: 253 GKNLAIVDSSIEAHMLDLLIYRETAKVLPNEGSHSYMICGKSCLAGDVFGEFRFAEELKV 312 Query: 378 GDWMLFENMGAYTVAAASTFNGFQRPNIY 406 GD + F++ YT+ + FNG + P I Sbjct: 313 GDRISFQDAAGYTMVKKNWFNGVKMPAIA 341 >3NZP-A nrPDB Length = 619 Score = 92.1 bits (227), Expect = 4e-19, Method: Composition-based stats. Identities = 49/256 (19%), Positives = 88/256 (34%), Gaps = 31/256 (12%) Query: 66 YAVKCNDSRAIVSTLAAIG----TGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIK 121 Y +K N V L +G G + SK E+ L + K I Sbjct: 83 YPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNG-FKDRELIN 141 Query: 122 Y---AASNGVQM-MTFDSEIELMKV-----ARAHPKAKLVLRIATDDSKAV-----CRLS 167 AA G + +T + EL + R PK + LR+ + ++ Sbjct: 142 IGFIAAEMGHNITLTIEGLNELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGIN 201 Query: 168 VKFGATLKTSRLLLERAKELNI--DVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEV 225 KFG T + KE + + FH+GS T+ +A+++A ++ ++ Sbjct: 202 SKFGLTSTELIEAVNLLKENKLLEQFTMIHFHLGSQITEIHPLKKALNEAGNIYTELRKM 261 Query: 226 GF-SMHLLDIGGGFPGSEDTKLK-------FEEITSVINPALDKYFPSDSGVR--IIAEP 275 G ++ +++GGG E + + L + I E Sbjct: 262 GAKNLKAINLGGGLAVEYSQFKNEKSRNYTLREYANDVVFILKNIAEQKKDLEPDIFIES 321 Query: 276 GRYYVASAFTLAVNII 291 GR+ A+ L ++ Sbjct: 322 GRFVAANHAVLIAPVL 337 Score = 33.9 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 49/133 (36%), Gaps = 11/133 (8%) Query: 286 LAVNIIAKKTV---WKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQK 342 + ++I KK + +Q +D +E Y VN ++ S + ++ Sbjct: 407 ILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSM-PDFWGLEQNFPIMPL 465 Query: 343 RPKPDEKYYSSSIWGPTCDGLDRIVERCNLPE-MHVGD------WMLFENMGAYTVAAAS 395 +E S+SIW TCD I + P +H D ++ F +GAY Sbjct: 466 DRLDEEPTRSASIWDITCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGM 525 Query: 396 TFNGFQRPNIYYV 408 N F P + Sbjct: 526 KHNLFTHPTEAII 538 >3N2O-A nrPDB Length = 648 Score = 90.9 bits (224), Expect = 9e-19, Method: Composition-based stats. Identities = 61/277 (22%), Positives = 102/277 (36%), Gaps = 37/277 (13%) Query: 66 YAVKCNDSRAIV-STLAAIG------TGFDCASKTEIQLVQGLGVPAERVIYANPCKQVS 118 Y +K N R +V LA+ G + SK E+ V + A VI N K Sbjct: 102 YPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDRE 161 Query: 119 QIKYAA---SNGVQMMTF-DSEIELMKVARAH------PKAKLVLRIATDDS---KAVCR 165 I+ A G ++ + EL V R P+ + +R+A+ + +A Sbjct: 162 YIRLALIGEKLGHKVFIVLEKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGG 221 Query: 166 LSVKFGATLKTSRLLLERAKELN----IDVIGVSFHVGSGCTDPETFVQAVSDARCVFDM 221 KFG + ++ R K+ N + + V FH+GS + V+++ + Sbjct: 222 EKSKFGLSASQVLNVISRLKKENQLDTLQL--VHFHLGSQMANIRDVRNGVNESARFYCE 279 Query: 222 ATEVGFSMHLLDIGGGFPGSEDTKL----------KFEEITSVINPALDKYFPSDSGVRI 271 +G ++ D+GGG D E +++N D + + Sbjct: 280 LRTLGANITYFDVGGGLAIDYDGTRSQSSNSMNYGLVEYARNIVNTVGDVCKDYKQPMPV 339 Query: 272 IA-EPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDED 307 I E GR A L N+I +T E +ED Sbjct: 340 IISESGRSLTAHHAVLISNVIGTETYKPETVTEPEED 376 >3NZQ-A nrPDB Length = 666 Score = 89.0 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 57/312 (18%), Positives = 100/312 (32%), Gaps = 39/312 (12%) Query: 66 YAVKCNDSRAIVSTLAAIG--TGFDCASKTEIQLVQ-GLGVPAERVIYANPCKQVSQIKY 122 Y +K N R ++ +L G G + SK E+ V G+ ++ K I+ Sbjct: 124 YPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNG-YKDREYIRL 182 Query: 123 AA---SNGVQM-MTFDSEIELMKVARAHPKAKLVLRIATDDSKAV---------CRLSVK 169 A G ++ + + E+ V + +V R+ A K Sbjct: 183 ALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSK 242 Query: 170 FGATLKTSRLLLERAKELN----IDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEV 225 FG L+E +E + + + FH+GS + V ++ + ++ Sbjct: 243 FGLAATQVLQLVETLREAGRLDSLQL--LHFHLGSQMANIRDIATGVRESARFYVELHKL 300 Query: 226 GFSMHLLDIGGGFPGSEDTK---------LKFEEITSVINPALDKYFPSD--SGVRIIAE 274 G ++ D+GGG + E + I A+ + +I E Sbjct: 301 GVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEENGLPHPTVITE 360 Query: 275 PGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMY-----YVNDGVYGSFNCI 329 GR A L NII + P + ED M+ G S Sbjct: 361 SGRAVTAHHTVLVSNIIGVERNEYTVPTAPAEDAPRALQSMWETWQEMHEPGTRRSLREW 420 Query: 330 LYDHAHVKALLQ 341 L+D + Sbjct: 421 LHDSQMDLHDIH 432 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 38/123 (30%), Gaps = 16/123 (13%) Query: 318 VNDGVYGSFN--CILYDHA---HVKALLQKRPKPDEKYYSSSIWGPTCDG---------L 363 + D +Y +F+ + D + +L + + TCD Sbjct: 481 MADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDG 540 Query: 364 DRIVERCNLPEMHVGD--WMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQ 421 D I +PE + + F +GAY + N F V P + ++ Sbjct: 541 DGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELS 600 Query: 422 SHG 424 G Sbjct: 601 DEG 603 >3N29-A nrPDB Length = 418 Score = 87.5 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 71/397 (17%), Positives = 141/397 (35%), Gaps = 33/397 (8%) Query: 37 KDAFYVADLGDILKK--HLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 + Y+ + + K L + A+K + + G C+ E Sbjct: 43 QTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLWE 102 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLR 154 + + + E Y+ K+ + A+ + + F+S + K K L LR Sbjct: 103 AKFAKEY-MDKEIHTYSPAFKEDEIGEIASLS--HHIVFNSLAQFHKFQSKTQKNSLGLR 159 Query: 155 IATDDSKAVCRLSVKFGATLKTSRLLLERAKELNID---VIGVSFHVGSGCTDPETFVQA 211 + S A L G + SRL + N+D + G+ FH E A Sbjct: 160 CNVEFSLAPKELYNPCG---RYSRLGIRAKDFENVDLNAIEGLHFH-----ALCEESADA 211 Query: 212 VSDARCVFDMATEVGF---SMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSG 268 + VF+ + G M ++ GGG ++ E++ AL K F G Sbjct: 212 LEAVLKVFE--EKFGKWIGQMKWVNFGGGHHITK-KGYDVEKLI-----ALCKNFSDKYG 263 Query: 269 VRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNC 328 V++ EPG L +++ + E+ + + S + N Sbjct: 264 VQVYLEPGEAVGWQTGNLVASVV--DIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNA 321 Query: 329 ILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGA 388 + + + + ++ + G TC D + E ++ +GD ++F + Sbjct: 322 RILATRENEKISDLKENE----FAYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIH 377 Query: 389 YTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGF 425 YT+ +TFNG + PN+ + + Q++++ + Sbjct: 378 YTIVKNTTFNGIRLPNLMLLDHKNELQMIREFSYKDY 414 >3KS6-A nrPDB Length = 250 Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 8/100 (8%) Query: 38 DAFYVADLGDILKKHLR---WLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTE 94 +F +A + ++ K R WL + P V AI ++ IG D A Sbjct: 138 SSFLLASMDELWKATTRPRLWLVS-PSVLQQLGPGAVIETAIAHSIHEIGVHIDTADAGL 196 Query: 95 IQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFD 134 + VQ G+ SQI A GV++ T D Sbjct: 197 MAQVQAAGLDFGCWAAH----TPSQITKALDLGVKVFTTD 232 >6NXI-A nrPDB Length = 328 Score = 32.8 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 10/85 (11%) Query: 205 PETFVQAVSDARC-----VFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPAL 259 PE +V + A+ V D G ++++IGG L + + A+ Sbjct: 147 PELYVDLSTIAKGWGVDVVADYLQSQGIENYMVEIGG---EIRLKGLNRDGVP--WRIAI 201 Query: 260 DKYFPSDSGVRIIAEPGRYYVASAF 284 +K V+ I EPG Y +A++ Sbjct: 202 EKPSVDQRSVQEIIEPGDYAIATSG 226 >5LDA-A nrPDB Length = 130 Score = 32.0 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 168 VKFGATLKTSRLLLERAKELNIDVIGV-SFHV 198 V+F + LE A++ N++V+G+ H+ Sbjct: 50 VEFEMDPEEMLKALEEAEQENLEVVGIFHSHI 81 >4AWE-A nrPDB Length = 387 Score = 32.0 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 26/80 (32%), Gaps = 9/80 (11%) Query: 199 GSGCTDPETFVQAVSDARCV-FDMATEV--------GFSMHLLDIGGGFPGSEDTKLKFE 249 G+ D F + V A + + G ++ +++GG + T K + Sbjct: 94 GTQTIDVSPFDKVVDSATKTGIKLIVALTNNWADYGGMDVYTVNLGGKYHDDFYTVPKIK 153 Query: 250 EITSVINPALDKYFPSDSGV 269 E A+ + + Sbjct: 154 EAFKRYVKAMVTRYRDSEAI 173 >4DEF-A nrPDB Length = 349 Score = 31.2 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 5/56 (8%) Query: 88 DCASKTEIQLVQGLGVPAE----RVIYAN-PCKQVSQIKYAASNGVQMMTFDSEIE 138 D ++ + LG+PA+ ++ S+I+ A GV M D++ + Sbjct: 225 DILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQ 280 >2X0S-A nrPDB Length = 913 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 51/158 (32%), Gaps = 27/158 (17%) Query: 44 DLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGV 103 DL + L+W + + R+ A + A G G + + + Sbjct: 542 DLKGSFQTILQWCQEMKRLGVRTNADTPADAAKARSFGAEGVG--------LCRTEHMFF 593 Query: 104 PAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMK-----VARAHPKAKLVLRI--- 155 R+ + + ++ A S + D + + + + RA + +R+ Sbjct: 594 EGSRINF------IREMILADSASGRKAALDKLLPIQRADFVGILRAMRGLPVTIRLLDP 647 Query: 156 -----ATDDSKAVCRLSVKFGATLKTSRLLLERAKELN 188 D+ A L+ K G + R + ELN Sbjct: 648 PLHEFVPHDAAAQFELAQKLGMPAEKVRNRVNALHELN 685 >5BSW-A nrPDB Length = 541 Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 50/144 (34%), Gaps = 22/144 (15%) Query: 96 QLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIE----LMKVARAHPKAKL 151 ++V+ + ++I C YA N V+++ DS E + +A+ Sbjct: 115 EVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIP 174 Query: 152 VLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCT--DPETFV 209 + I DD A+ S G K + + G+ V +P ++ Sbjct: 175 EVEIQPDDVVALPYSSGTTGLP-----------KGVMLTHKGLVTSVAQQVDGENPNLYI 223 Query: 210 QAVSDARCVFDMATEVGFSMHLLD 233 + CV + F ++ L+ Sbjct: 224 HSEDVMLCVLPL-----FHIYSLN 242 >2IX4-A nrPDB Length = 431 Score = 30.1 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 24/63 (38%), Gaps = 6/63 (9%) Query: 166 LSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEV 225 LS KF ++ + + + ++ VIG GSG E + A ++ Sbjct: 224 LSTKFNSSPQEASRPFDCDRDGF--VIG----EGSGVIVLEEYEHAKRRGAKIYAELCGY 277 Query: 226 GFS 228 G S Sbjct: 278 GMS 280 >5X5Y-G nrPDB Length = 355 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 3/48 (6%) Query: 64 PFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYA 111 P A A++ L +GT AS +E+ +++ GV R+++A Sbjct: 57 PRRAYDMLPMAALIGCLVGLGT---LASNSELTIMRAAGVSLSRIVWA 101 >2C2L-A nrPDB Length = 281 Score = 28.9 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 160 SKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVF 219 ++A+C L ++ + + RA EL+ + F +G + E++ +A+++ + + Sbjct: 43 NRALCYLKMQ---QPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAY 99 Query: 220 DMATE 224 +A E Sbjct: 100 SLAKE 104 >5TOO-A nrPDB Length = 549 Score = 28.9 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 28/79 (35%), Gaps = 2/79 (2%) Query: 201 GCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFP-GSEDTKLKFEEITSVINPAL 259 + ++ A S + + LL +G G G + +I ++ L Sbjct: 457 QIISKDGYLSAYSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLL 516 Query: 260 DKYFPSDSGVRIIAE-PGR 277 FPS + + I E GR Sbjct: 517 KIQFPSGAVGKPITEVIGR 535 >3AQ1-B nrPDB Length = 500 Score = 28.5 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 12/95 (12%) Query: 130 MMTFDSEIELMKVARAHPKAKLVLRIA-TDDSKAVCRLSVKFGATLKTSRLLLERAKELN 188 ++T D L ++ HP AK+++ ++ T D++ G T +K Sbjct: 10 VITNDGATILKEMDIQHPAAKMIVEVSKTQDAEVGD------GTTTAAVLSGELLSKAEE 63 Query: 189 IDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMAT 223 + + GV + S E + A R + + T Sbjct: 64 LIMKGVHSTIIS-----EGYRHAAEKCREILETIT 93 >3K5T-A nrPDB Length = 731 Score = 28.5 bits (62), Expect = 7.0, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 20/68 (29%), Gaps = 5/68 (7%) Query: 180 LLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFP 239 + V+ V F G + +V +A ++ T G LD+G G Sbjct: 305 AFRLRSSSGLQVLNVHFG-GERI----AYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLG 359 Query: 240 GSEDTKLK 247 Sbjct: 360 SVTHELAP 367 >5MRC-1 nrPDB Length = 348 Score = 28.2 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 40/107 (37%), Gaps = 11/107 (10%) Query: 254 VINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQT 313 V ++ FP +GV EPG + L+ N+ + + ++K Q E T Sbjct: 154 VPRAEVNIKFPFSTGVNKWIEPGEF-------LSSNVTSMRPIFKIQEYELVNVEKQLYT 206 Query: 314 FMYY---VNDGVYGSFNCIL-YDHAHVKALLQKRPKPDEKYYSSSIW 356 + V D SF L Y ++ K++SS+I Sbjct: 207 VLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNII 253 >1Q7Q-A nrPDB Length = 566 Score = 28.2 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 50/150 (33%), Gaps = 15/150 (10%) Query: 140 MKVARAHPKAKLVLRIATDDS---KAVCRLSVKFGATLK-TSRLLLERAKEL-NIDVIGV 194 K+ K + I + K L V FG + R + + + L + + + Sbjct: 328 KKLWAEMQKGNEEIVIKEAKTQVEKGAEVLDVNFGIESQIDVRYVEKIVQTLPYVSNVPL 387 Query: 195 SFHVGSGCTDPETFVQAVSDARCVFDMA----TEVGFSMHLLDIGGG----FPGSEDTKL 246 S + D R +F+ A E+ ++LL GG +D Sbjct: 388 SLDI--QNVDLTERALRAYPGRSLFNSAKVDEEELEMKINLLKKYGGTLIVLLMGKDVPK 445 Query: 247 KFEEITSVINPALDKYFPSDSGVRIIAEPG 276 FEE AL D R+I +PG Sbjct: 446 SFEERKEYFEKALKILERHDFSDRVIFDPG 475 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.130 0.344 Lambda K H 0.267 0.0396 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,673,163 Number of Sequences: 36641 Number of extensions: 629548 Number of successful extensions: 2098 Number of sequences better than 10.0: 43 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1923 Number of HSP's gapped (non-prelim): 78 length of query: 461 length of database: 10,336,785 effective HSP length: 100 effective length of query: 361 effective length of database: 6,672,685 effective search space: 2408839285 effective search space used: 2408839285 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.2 bits)