BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00787 (339 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1MIR-A nrPDB 661 0.0 3PBH-A nrPDB 557 e-159 1CPJ-A nrPDB 538 e-153 3CBK-A nrPDB 469 e-133 2DCB-A nrPDB 436 e-123 1CSB-B nrPDB 371 e-103 1SP4-B nrPDB 340 4e-94 4I04-A nrPDB 331 3e-91 4I05-A nrPDB 318 2e-87 5OGQ-A nrPDB 317 4e-87 4HWY-A nrPDB 248 4e-66 5FPW-A nrPDB 202 1e-52 3PDF-A nrPDB 121 5e-28 1JQP-A nrPDB 115 2e-26 1NB3-A nrPDB 109 2e-24 6CZS-A nrPDB 102 2e-22 3QJ3-A nrPDB 102 2e-22 2O6X-A nrPDB 100 1e-21 4P6E-A nrPDB 98 4e-21 2C0Y-A nrPDB 96 2e-20 4BS5-A nrPDB 96 2e-20 7PCK-A nrPDB 94 1e-19 4PI3-A nrPDB 89 2e-18 3OF9-A nrPDB 89 2e-18 4YYW-A nrPDB 89 3e-18 1DEU-A nrPDB 89 3e-18 3KFQ-A nrPDB 89 3e-18 1AEC-A nrPDB 89 3e-18 3HWN-A nrPDB 89 3e-18 4QRX-A nrPDB 88 5e-18 5JA7-A nrPDB 88 6e-18 6MIS-A nrPDB 87 1e-17 5JT8-A nrPDB 87 1e-17 1CJL-A nrPDB 87 1e-17 2ACT-A nrPDB 86 2e-17 1EF7-A nrPDB 86 2e-17 2VHS-A nrPDB 86 3e-17 3P5W-A nrPDB 85 3e-17 4YYR-A nrPDB 83 1e-16 6EXO-A nrPDB 83 2e-16 6BKI-A nrPDB 81 6e-16 1S4V-A nrPDB 81 8e-16 3QT4-A nrPDB 80 1e-15 2CIO-A nrPDB 77 8e-15 1CQD-A nrPDB 77 1e-14 2FO5-A nrPDB 77 2e-14 4YYQ-A nrPDB 76 2e-14 4OEL-A nrPDB 75 4e-14 5VPK-A nrPDB 74 7e-14 4CDF-B nrPDB 74 9e-14 3BPF-A nrPDB 73 2e-13 5EF4-A nrPDB 71 6e-13 1M6D-A nrPDB 70 2e-12 1PCI-A nrPDB 67 1e-11 1YAL-A nrPDB 67 1e-11 5A24-A nrPDB 65 3e-11 3BPM-A nrPDB 64 7e-11 5VCN-A nrPDB 64 8e-11 2BDZ-A nrPDB 63 1e-10 1IWD-A nrPDB 63 2e-10 1ICF-A nrPDB 62 3e-10 1PPO-A nrPDB 61 7e-10 1O0E-A nrPDB 60 1e-09 3BCN-A nrPDB 60 2e-09 4OEM-B nrPDB 60 2e-09 1XKG-A nrPDB 59 2e-09 2B1M-A nrPDB 59 3e-09 3F75-A nrPDB 59 4e-09 3U8E-A nrPDB 56 2e-08 1GEC-E nrPDB 56 3e-08 2PNS-A nrPDB 56 3e-08 5I4H-B nrPDB 53 2e-07 5I4H-A nrPDB 51 9e-07 3IOQ-A nrPDB 50 1e-06 3CH2-X nrPDB 50 2e-06 3OIS-A nrPDB 31 0.80 4K7C-A nrPDB 29 3.4 4KPO-A nrPDB 28 7.1 1E5M-A nrPDB 28 7.7 >1MIR-A nrPDB Length = 322 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/322 (98%), Positives = 318/322 (98%) Query: 18 HDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPNLPERVGFSED 77 HDKPS HPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGP LPERVGFSED Sbjct: 1 HDKPSFHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPKLPERVGFSED 60 Query: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 INLPESFDAREQWSNCPTIAQIRDQGSCGS WAFGAVEAMSDRICIHTNGRVNVEVSAED Sbjct: 61 INLPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAED 120 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG+RPP Sbjct: 121 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPP 180 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS Sbjct: 181 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 240 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWN DWGDNGFFKILRGEN Sbjct: 241 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGEN 300 Query: 318 HCGIESEIVAGIPRTQQYWGRF 339 HCGIESEIVAGIPRTQQYWGRF Sbjct: 301 HCGIESEIVAGIPRTQQYWGRF 322 >3PBH-A nrPDB Length = 317 Score = 557 bits (1436), Expect = e-159, Method: Compositional matrix adjust. Identities = 254/313 (81%), Positives = 287/313 (91%) Query: 20 KPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPNLPERVGFSEDIN 79 +PS HPLSD+++NY+NK+NTTWQAG NFYNVD+SYLK+LCGT LGGP P+RV F+ED+ Sbjct: 4 RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK 63 Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP SFDAREQW CPTI +IRDQGSCGSCWAFGAVEA+SDRICIHTN V+VEVSAEDLL Sbjct: 64 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 123 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 TCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCEHHVNGSRPPCT Sbjct: 124 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 183 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 GEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF+V+SDF Sbjct: 184 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 243 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 L YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKILRG++HC Sbjct: 244 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 303 Query: 320 GIESEIVAGIPRT 332 GIESE+VAGIPRT Sbjct: 304 GIESEVVAGIPRT 316 >1CPJ-A nrPDB Length = 260 Score = 538 bits (1385), Expect = e-153, Method: Compositional matrix adjust. Identities = 258/260 (99%), Positives = 259/260 (99%) Query: 74 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 133 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV Sbjct: 1 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 60 Query: 134 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG Sbjct: 61 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 120 Query: 194 SRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 180 Query: 254 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKIL 313 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWN DWGDNGFFKIL Sbjct: 181 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 240 Query: 314 RGENHCGIESEIVAGIPRTQ 333 RGENHCGIESEIVAGIPRTQ Sbjct: 241 RGENHCGIESEIVAGIPRTQ 260 >3CBK-A nrPDB Length = 266 Score = 469 bits (1208), Expect = e-133, Method: Compositional matrix adjust. Identities = 215/266 (80%), Positives = 241/266 (90%) Query: 74 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 133 F+ED+ LP SFDAREQW CPTI +IRDQGSCGS WAFGAVEA+SDRICIHTN V+VEV Sbjct: 1 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEV 60 Query: 134 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 SAEDLLTCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCE HVNG Sbjct: 61 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNG 120 Query: 194 SRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 180 Query: 254 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKIL 313 +V+SDFL YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKIL Sbjct: 181 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 240 Query: 314 RGENHCGIESEIVAGIPRTQQYWGRF 339 RG++HCGIESE+VAGIPRT QYW + Sbjct: 241 RGQDHCGIESEVVAGIPRTDQYWEKI 266 >2DCB-A nrPDB Length = 256 Score = 436 bits (1121), Expect = e-123, Method: Compositional matrix adjust. Identities = 215/256 (83%), Positives = 241/256 (94%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPESFDAREQW NCPTI +IRDQGSCGSCWAFGAVEA+SDRICIH+NGRVNVEVSAED+L Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 TCCG +CGDGCNGG+PSGAWNFWT+KGLVSGG+YNSH+GC PY+IPPCEHHVNGSRPPCT Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 GEGDTPKC+K CE GYS SYKEDKH+G +SYSV+++EKEIMAEIYKNGPVEGAF+V+SDF Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDF 180 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 L YKSGVY+H +G++MGGHAIRILGWG+ENG PYWLV NSWN DWGDNGFFKILRG++HC Sbjct: 181 LLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHC 240 Query: 320 GIESEIVAGIPRTQQY 335 GIESEIVAG+P T QY Sbjct: 241 GIESEIVAGMPCTHQY 256 >1CSB-B nrPDB Length = 205 Score = 371 bits (953), Expect = e-103, Method: Compositional matrix adjust. Identities = 171/205 (83%), Positives = 191/205 (93%) Query: 129 VNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCE 188 V+VEVSAEDLLTCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCE Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 189 HHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGP 248 HHVNGSRPPCTGEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGP Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 120 Query: 249 VEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNG 308 VEGAF+V+SDFL YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNG Sbjct: 121 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 180 Query: 309 FFKILRGENHCGIESEIVAGIPRTQ 333 FFKILRG++HCGIESE+VAGIPRT Sbjct: 181 FFKILRGQDHCGIESEVVAGIPRTD 205 >1SP4-B nrPDB Length = 205 Score = 340 bits (873), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 171/205 (83%), Positives = 193/205 (94%) Query: 128 RVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPC 187 RVNVEVSAED+LTCCG +CGDGCNGG+PSGAWNFWT+KGLVSGG+YNSH+GC PY+IPPC Sbjct: 1 RVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPC 60 Query: 188 EHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNG 247 EHHVNGSRPPCTGEGDTPKCNK CE GYS SYKEDKH+G +SYSV+++EKEIMAEIYKNG Sbjct: 61 EHHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNG 120 Query: 248 PVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDN 307 PVEGAF+V+SDFL YKSGVY+H +G++MGGHAIRILGWG+ENG PYWLV NSWN DWGDN Sbjct: 121 PVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDN 180 Query: 308 GFFKILRGENHCGIESEIVAGIPRT 332 GFFKILRG++HCGIESEIVAG+P T Sbjct: 181 GFFKILRGQDHCGIESEIVAGMPCT 205 >4I04-A nrPDB Length = 323 Score = 331 bits (849), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 160/313 (51%), Positives = 212/313 (67%), Gaps = 12/313 (3%) Query: 25 PLSDDMINYINKQ-NTTWQAGRN--FYNVDISYLKKLCGTVLGGPNLPERVGFSED---- 77 PLSDD+I+YIN+ N W+A ++ F+++D + ++ G P+L + D Sbjct: 11 PLSDDIISYINEHPNAGWRAEKSNRFHSLDDARIQ--MGARREEPDLRRTRRPTVDHNDW 68 Query: 78 -INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAE 136 + +P SFD+R++W C +IA IRDQ CGS WAFGAVEAMSDR CI + G+ NVE+SA Sbjct: 69 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAV 128 Query: 137 DLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRP 196 DLL+CC CG GC GG AW++W ++G+V+G +H GC PY P CEHH G P Sbjct: 129 DLLSCCE-SCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 187 Query: 197 PCTGE-GDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV 255 PC + TP+C + C+ Y T Y +DKH G +SY+V + EK I EI K GPVE FTV Sbjct: 188 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 247 Query: 256 FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 + DFL YKSG+YKH G+ +GGHAIRI+GWG+EN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 248 YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRG 307 Query: 316 ENHCGIESEIVAG 328 + C IESE+ AG Sbjct: 308 RDECSIESEVTAG 320 >4I05-A nrPDB Length = 285 Score = 318 bits (815), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 143/253 (56%), Positives = 182/253 (71%), Gaps = 2/253 (0%) Query: 77 DINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAE 136 ++ +P SFD+R++W C +IA IRDQ CGSCWAFGAVEAMSDR CI + G+ NVE+SA Sbjct: 31 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAV 90 Query: 137 DLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRP 196 DLL+CC CG GC GG AW++W ++G+V+G +H GC PY P CEHH G P Sbjct: 91 DLLSCCE-SCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 149 Query: 197 PCTGE-GDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV 255 PC + TP+C + C+ Y T Y +DKH G +SY+V + EK I EI K GPVE FTV Sbjct: 150 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 209 Query: 256 FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 + DFL YKSG+YKH G+ +GGHAIRI+GWG+EN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 210 YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRG 269 Query: 316 ENHCGIESEIVAG 328 + C IESE+ AG Sbjct: 270 RDECSIESEVTAG 282 >5OGQ-A nrPDB Length = 254 Score = 317 bits (812), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 143/252 (56%), Positives = 181/252 (71%), Gaps = 2/252 (0%) Query: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 + +P SFD+R++W C +IA IRDQ CGSCWAFGAVEAMSDR CI + G+ NVE+SA D Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 LL+CC CG GC GG AW++W ++G+V+G +H GC PY P CEHH G PP Sbjct: 61 LLSCCE-SCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPP 119 Query: 198 CTGE-GDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 C + TP+C + C+ Y T Y +DKH G +SY+V + EK I EI K GPVE FTV+ Sbjct: 120 CGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVY 179 Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE 316 DFL YKSG+YKH G+ +GGHAIRI+GWG+EN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 180 EDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGR 239 Query: 317 NHCGIESEIVAG 328 + C IESE+ AG Sbjct: 240 DECSIESEVTAG 251 >4HWY-A nrPDB Length = 340 Score = 248 bits (632), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 140/316 (44%), Positives = 181/316 (57%), Gaps = 24/316 (7%) Query: 26 LSDDMINYINKQNT-TWQAGRN--FYNVDISYLKKLCGTVLGGPN---LPERVGFSEDIN 79 LS ++ +N+ N W+A + N+ + K+L G + N LP+R E+ Sbjct: 32 LSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEAR 91 Query: 80 --LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 LP SFD+ E W NCPTI QI DQ +CGSCWA A AMSDR C G +V +SA D Sbjct: 92 APLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCT-MGGVQDVHISAGD 150 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSR-- 195 LL CC CGDGCNGG P AW +++ GLVS C PY P C HH Sbjct: 151 LLACCS-DCGDGCNGGDPDRAWAYFSSTGLVSDY-------CQPYPFPHCSHHSKSKNGY 202 Query: 196 PPCTG-EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFT 254 PPC+ DTPKCN C+ + + +TSY++ E + M E++ GP E AF Sbjct: 203 PPCSQFNFDTPKCNYTCD---DPTIPVVNYRSWTSYALQ-GEDDYMRELFFRGPFEVAFD 258 Query: 255 VFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 V+ DF+ Y SGVY H +G +GGHA+R++GWG NGVPYW +ANSWN +WG +G+F I R Sbjct: 259 VYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRR 318 Query: 315 GENHCGIESEIVAGIP 330 G + CGIE AGIP Sbjct: 319 GSSECGIEDGGSAGIP 334 >5FPW-A nrPDB Length = 321 Score = 202 bits (515), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 122/317 (38%), Positives = 168/317 (52%), Gaps = 20/317 (6%) Query: 26 LSDDMINYINKQNT-TWQAGRN--FYNVDISYLKKLCGTVLGGPNLPERVGFSED---IN 79 L+ ++ IN+ N W+A N N+ + K+L G + + V F+E+ Sbjct: 15 LTKTFVDRINQLNGGMWKAVYNGKMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTE 74 Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPESFD+ E+W NCPTI +I DQ +C + WA +SDR C G + +SA LL Sbjct: 75 LPESFDSAEKWPNCPTIREIADQSACRASWAVSTASVISDRYCT-VGGVQQLRISAAHLL 133 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHH-VNGSRPPC 198 +CC G GG+P AW ++ G+ S C PY P CEH G++ PC Sbjct: 134 SCCKQCGGGC-KGGFPGFAWRYYVEYGIASSY-------CQPYPFPHCEHRGAQGNKTPC 185 Query: 199 TGEG-DTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 + DTPKC C S K+ G +Y + E++ E+Y NGP F V++ Sbjct: 186 SKYNFDTPKCQATCT---DKSIPLVKYRGSATYLLLHGEEDYKRELYFNGPFVAVFYVYT 242 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 D YKSGVY+H GD +GG A++++GWG NG PYW VAN+W+ DWG +G+ ILRG N Sbjct: 243 DLFAYKSGVYRHVDGDFLGGTAVKVVGWGKLNGTPYWKVANTWDTDWGMDGYLLILRGNN 302 Query: 318 HCGIESEIVAGIPRTQQ 334 C IE AG P T Q Sbjct: 303 ECNIEHLGFAGTPETSQ 319 >3PDF-A nrPDB Length = 441 Score = 121 bits (303), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 88/263 (33%), Positives = 128/263 (48%), Gaps = 46/263 (17%) Query: 80 LPESFDAREQWSNCPTI---AQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAE 136 LP S+D W N I + +R+Q SCGSC++F ++ + RI I TN +S + Sbjct: 207 LPTSWD----WRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQ 262 Query: 137 DLLTCCGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSR 195 ++++C Q GC GG+P A + GLV C PYT G+ Sbjct: 263 EVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT---------GTD 304 Query: 196 PPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV 255 PC + D C YS+ Y HY Y + E + E+ +GP+ AF V Sbjct: 305 SPCKMKED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAFEV 352 Query: 256 FSDFLTYKSGVYKHEAGD------VMGGHAIRILGWGIEN--GVPYWLVANSWNVDWGDN 307 + DFL YK G+Y H + HA+ ++G+G ++ G+ YW+V NSW WG+N Sbjct: 353 YDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGEN 412 Query: 308 GFFKILRGENHCGIESEIVAGIP 330 G+F+I RG + C IES VA P Sbjct: 413 GYFRIRRGTDECAIESIAVAATP 435 >1JQP-A nrPDB Length = 438 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 96/324 (29%), Positives = 146/324 (45%), Gaps = 60/324 (18%) Query: 29 DMINYINKQNTTWQAG--RNFYNVDISYLKKLCG---TVLGGPNLPERVGFSEDI-NLPE 82 + + IN +W A R + + I L + G +L P + I +LPE Sbjct: 149 NFVKAINSVQKSWTATTYRRYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPE 208 Query: 83 SFDAREQWSNCPTI---AQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 S+D W N I + +R+Q SCGSC++F ++ + RI I TN +S ++++ Sbjct: 209 SWD----WRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 264 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIG-----CLPYTIPPCEHHVNGS 194 +C GC+GG+P + G Y G C PYT + Sbjct: 265 SCSPY--AQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT---------AT 302 Query: 195 RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFT 254 PC PK N C YS+ Y + +E + E+ K+GP+ AF Sbjct: 303 DAPCK-----PKEN--CLRYYSSEYYYV-----GGFYGGCNEALMKLELVKHGPMAVAFE 350 Query: 255 VFSDFLTYKSGVYKHEAGD------VMGGHAIRILGWGIE--NGVPYWLVANSWNVDWGD 306 V DFL Y SG+Y H + HA+ ++G+G + G+ YW+V NSW WG+ Sbjct: 351 VHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGE 410 Query: 307 NGFFKILRGENHCGIESEIVAGIP 330 +G+F+I RG + C IES +A IP Sbjct: 411 SGYFRIRRGTDECAIESIAMAAIP 434 >1NB3-A nrPDB Length = 220 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 78/258 (30%), Positives = 124/258 (48%), Gaps = 49/258 (18%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D R++ + ++ +++QGSCGSCW F A+ + I T G++ + ++ + L+ Sbjct: 2 PPSMDWRKKGN---FVSPVKNQGSCGSCWTFSTTGALESAVAIAT-GKM-LSLAEQQLVD 56 Query: 141 CCGIQCGDGCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC GG PS A+ + KG++ Y P Sbjct: 57 CAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTY-----------------------PYK 93 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTS--YSVSDSEKEIMAE-IYKNGPVEGAFTVF 256 G+ D K ++ DK + +++ +++E M E + PV AF V Sbjct: 94 GQDDHCK------------FQPDKAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEVT 141 Query: 257 SDFLTYKSGVYK----HEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKI 312 +DFL Y+ G+Y H+ D + HA+ +G+G ENG+PYW+V NSW WG NG+F I Sbjct: 142 NDFLMYRKGIYSSTSCHKTPDKVN-HAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLI 200 Query: 313 LRGENHCGIESEIVAGIP 330 RG+N CG+ + IP Sbjct: 201 ERGKNMCGLAACASYPIP 218 >6CZS-A nrPDB Length = 335 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 76/255 (29%), Positives = 122/255 (47%), Gaps = 43/255 (16%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D R++ + ++ +++QG+CGS W F A+ I I T G++ + ++ + L+ Sbjct: 117 PPSVDWRKKGN---FVSPVKNQGACGSSWTFSTTGALESAIAIAT-GKM-LSLAEQQLVD 171 Query: 141 CCGIQCGDGCNGGYPSGAWNF-WTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC GG PS A+ + KG++ Y PY Sbjct: 172 CAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTY-------PY----------------- 207 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 +G C + G + + +D + ++ D E + A N PV AF V DF Sbjct: 208 -QGKDGYCK--FQPGKAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDF 259 Query: 260 LTYKSGVYK----HEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 + Y++G+Y H+ D + HA+ +G+G +NG+PYW+V NSW WG NG+F I RG Sbjct: 260 MMYRTGIYSSTSCHKTPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERG 318 Query: 316 ENHCGIESEIVAGIP 330 +N CG+ + IP Sbjct: 319 KNMCGLAACASYPIP 333 >3QJ3-A nrPDB Length = 331 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/263 (30%), Positives = 116/263 (44%), Gaps = 41/263 (15%) Query: 70 ERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRV 129 E +G + + P SFD R+Q P +++QGSCGS WAF + A+ ++ I Sbjct: 106 EDLGLNASVRYPASFDWRDQGMVSP----VKNQGSCGSSWAFSSTGAIESQMKIANGAGY 161 Query: 130 NVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEH 189 + VS + L+ C + GC+GG+ + A+ + + G + G PY + Sbjct: 162 DSSVSEQQLVDC--VPNALGCSGGWMNDAFTYVAQNGGIDSE------GAYPYEMADGNC 213 Query: 190 HVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPV 249 H Y + + GY S D E + + GPV Sbjct: 214 H------------------------YDPNQVAARLSGYVYLSGPD-ENMLADMVATKGPV 248 Query: 250 EGAFTVFSDFLTYKSGVYKHEAGDVMG-GHAIRILGWGIENGVPYWLVANSWNVDWGDNG 308 AF F +Y GVY + + HA+ I+G+G ENG YWLV NSW WG +G Sbjct: 249 AVAFDADDPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWGLDG 308 Query: 309 FFKILR-GENHCGIESEIVAGIP 330 +FKI R NHCGI VA +P Sbjct: 309 YFKIARNANNHCGIAG--VASVP 329 >2O6X-A nrPDB Length = 310 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 116/258 (44%), Gaps = 42/258 (16%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P+ D W + +++DQG+CGS WAF M + N R ++ S + L+ Sbjct: 92 VPDKID----WRESGYVTEVKDQGNCGSGWAFSTTGTMEGQYM--KNERTSISFSEQQLV 145 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C +GC GG A+ + + GL + Y PYT + C Sbjct: 146 DCSRPWGNNGCGGGLMENAYQYLKQFGLETESSY-------PYTAVEGQ---------C- 188 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 + NK T + YT +S SE E+ + GP A V SDF Sbjct: 189 ------RYNKQLGVAKVTGF-------YTVHS--GSEVELKNLVGAEGPAAVAVDVESDF 233 Query: 260 LTYKSGVYKHEA-GDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE-N 317 + Y+SG+Y+ + + HA+ +G+G + G YW+V NSW + WG+ G+ +++R N Sbjct: 234 MMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGN 293 Query: 318 HCGIESEIVAGIPRTQQY 335 CGI S +A +P ++ Sbjct: 294 MCGIAS--LASLPMVARF 309 >4P6E-A nrPDB Length = 230 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 122/250 (48%), Gaps = 46/250 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+S D RE+ + +++ QGSCG+CWAF AV A+ ++ + T G++ V +SA++L+ Sbjct: 7 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT-GKL-VSLSAQNLV 60 Query: 140 TCCGIQCGD-GCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 C + G+ GCNGG+ + A+ + KG+ S Y PY Sbjct: 61 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKA------------- 100 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTS--YSVSDSEKEIMAEIYKNGPVE-GAFT 254 ++ C+ Y + Y+ YT Y D KE +A GPV G Sbjct: 101 ---------MDQKCQ--YDSKYRAATCSKYTELPYGREDVLKEAVAN---KGPVSVGVDA 146 Query: 255 VFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 147 RHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 206 Query: 315 GE-NHCGIES 323 + NHCGI S Sbjct: 207 NKGNHCGIAS 216 >2C0Y-A nrPDB Length = 315 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 119/250 (47%), Gaps = 46/250 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+S D RE+ C + +++ QGSCG+ WAF AV A+ ++ + T G++ V +SA++L+ Sbjct: 99 LPDSVDWREK--GC--VTEVKYQGSCGAAWAFSAVGALEAQLKLKT-GKL-VSLSAQNLV 152 Query: 140 TCCGIQCGD-GCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTI--PPCEHHVNGSR 195 C + G+ GCNGG+ + A+ + KG+ S Y PY C++ Sbjct: 153 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 205 Query: 196 PPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVE-GAFT 254 C+ + P Y D KE +A GPV G Sbjct: 206 ATCSKYTELP------------------------YGREDVLKEAVAN---KGPVSVGVDA 238 Query: 255 VFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 239 RHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 298 Query: 315 GE-NHCGIES 323 + NHCGI S Sbjct: 299 NKGNHCGIAS 308 >4BS5-A nrPDB Length = 225 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 117/248 (47%), Gaps = 41/248 (16%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP++ D RE+ + +++ QGSCG+CWAF AV A+ ++ + T G++ + +SA++L+ Sbjct: 8 LPDTVDWREK----GCVTEVKYQGSCGACWAFSAVGALEGQLKLKT-GKL-ISLSAQNLV 61 Query: 140 TCCGIQC--GDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 C + GC GGY + A+ + G + PY + H N Sbjct: 62 DCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADA------SYPYKAMDEKCHYNSKNRA 115 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVE-GAFTVF 256 T C++ Y + D+ KE +A GPV G Sbjct: 116 AT-------CSR---------------YIQLPFGDEDALKEAVA---TKGPVSVGIDASH 150 Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR-G 315 S F YKSGVY + H + ++G+G +G YWLV NSW +++GD G+ ++ R Sbjct: 151 SSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNN 210 Query: 316 ENHCGIES 323 +NHCGI S Sbjct: 211 KNHCGIAS 218 >7PCK-A nrPDB Length = 314 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 83/331 (25%), Positives = 144/331 (43%), Gaps = 62/331 (18%) Query: 19 DKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG----TVLGGPNLPERVGF 74 D+ S + + + YI+ N G + Y + +++L + + G +P Sbjct: 27 DEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSR 86 Query: 75 SEDI--------NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTN 126 S D P+S D R++ P +++QG CGSCWAF +V A+ ++ T Sbjct: 87 SNDTLYIPEWEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTG 142 Query: 127 GRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYT-- 183 +N+ S ++L+ C + DGC GGY + A+ + + +G+ S Y PY Sbjct: 143 KLLNL--SPQNLVDC--VSENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQ 191 Query: 184 IPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEI 243 C ++ G C G + P+ N EK + + Sbjct: 192 EESCMYNPTGKAAKCRGYREIPEGN---------------------------EKALKRAV 224 Query: 244 YKNGPVEGAFTV-FSDFLTYKSGVYKHEAGDVMG-GHAIRILGWGIENGVPYWLVANSWN 301 + GPV A + F Y GVY E+ + HA+ +G+GI+ G +W++ NSW Sbjct: 225 ARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWG 284 Query: 302 VDWGDNGFFKILRGENH-CGIESEIVAGIPR 331 +WG+ G+ + R +N+ CGI + +A P+ Sbjct: 285 ENWGNKGYILMARNKNNACGIAN--LASFPK 313 >4PI3-A nrPDB Length = 216 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 64/244 (26%), Positives = 109/244 (44%), Gaps = 33/244 (13%) Query: 86 AREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQ 145 A W + ++DQG CGSCWAF A+ + + + + N+ +E +L C + Sbjct: 4 AAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNL---SEQMLVSCD-K 59 Query: 146 CGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTP 205 GC+GG + A+ + ++ +G VY S P +GEG +P Sbjct: 60 TDSGCSGGLMNNAFEWIVQEN--NGAVYTED-----------------SYPYASGEGISP 100 Query: 206 KCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSG 265 C +G++ H + E +I A + NGPV A S ++TY G Sbjct: 101 PCTT---SGHTVGATITGHV-----ELPQDEAQIAAWLAVNGPVAVAVDA-SSWMTYTGG 151 Query: 266 VYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEI 325 V + + H + ++G+ VPYW++ NSW WG+ G+ +I +G N C ++ E Sbjct: 152 VMTSCVSEQLD-HGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEA 210 Query: 326 VAGI 329 + + Sbjct: 211 SSAV 214 >3OF9-A nrPDB Length = 221 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/250 (29%), Positives = 111/250 (44%), Gaps = 45/250 (18%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D RE+ P +++QG CGSCWAF A A+ ++ T GR+ + +S ++L+ Sbjct: 3 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKT-GRL-ISLSEQNLVD 56 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C G Q +GCNGG A+ + +GG+ + T C+++ S TG Sbjct: 57 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDTG 112 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 259 D PK EK +M + GP+ A F Sbjct: 113 FVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHESF 144 Query: 260 LTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNVDWGDNGFFKILR 314 L YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ + Sbjct: 145 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAK 204 Query: 315 G-ENHCGIES 323 NHCGI S Sbjct: 205 DRRNHCGIAS 214 >4YYW-A nrPDB Length = 220 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 75/251 (29%), Positives = 108/251 (43%), Gaps = 45/251 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D W + + IRDQG CGSCW F + + I T+ ++ S ++LL Sbjct: 1 LPETVD----WRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSL--SEQELL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 C GC GG+ A+++ + +G+ S Y PYT + C Sbjct: 55 DCAPSYKDLGCKGGWMDKAYDYIIKDRGITSESDY-------PYT---------ARKGAC 98 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 K E + S ED V ++ + + N PV A S Sbjct: 99 DS-------RKATEVVATISSYED---------VPADNEDALKKAVANQPVSVAIDASSA 142 Query: 259 FLT-YKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 + Y SGV+ G V HA+ ++G+G E+GV YWLV NSW WG+ G+ K+ R Sbjct: 143 AVKEYSSGVFVGSCG-VANDHAVVVVGYGTESGVNYWLVRNSWGTKWGEEGYMKLERDTA 201 Query: 318 H----CGIESE 324 H CGI E Sbjct: 202 HPAGKCGIAME 212 >1DEU-A nrPDB Length = 277 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 45/264 (17%) Query: 63 LGGPNLPERVGFSEDINLPESFDAREQWSNCPTI---AQIRDQ---GSCGSCWAFGAVEA 116 LG P + +LP+S+D W N + + R+Q CGSCWA + A Sbjct: 19 LGRTTYPRPHEYLSPADLPKSWD----WRNVDGVNYASITRNQHIPQYCGSCWAHASTSA 74 Query: 117 MSDRICIHTNGR-VNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNS 175 M+DRI I G + +S ++++ C C GG W++ + G+ Sbjct: 75 MADRINIKRKGAWPSTLLSVQNVIDCGN---AGSCEGGNDLSVWDYAHQHGIPD------ 125 Query: 176 HIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKE-DKHYGYTSYSVSD 234 C ++ + +C+K + G +KE YT + V D Sbjct: 126 ---------ETCNNY----------QAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGD 166 Query: 235 -----SEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIEN 289 +++MAEIY NGP+ Y G+Y H + + GWGI + Sbjct: 167 YGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISD 226 Query: 290 GVPYWLVANSWNVDWGDNGFFKIL 313 G YW+V NSW WG+ G+ +I+ Sbjct: 227 GTEYWIVRNSWGEPWGERGWLRIV 250 >3KFQ-A nrPDB Length = 221 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 115/252 (45%), Gaps = 46/252 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+S D W + +++Q CGSCWAF A A+ ++ T G++ V +S ++L+ Sbjct: 1 LPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKT-GKL-VSLSEQNLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKG-LVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 C Q GCNGG+ + A+ + G L S Y PY Sbjct: 55 DCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESY-------PYVA-------------- 93 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FS 257 +++C+ S +D G+T + EK +M + GP+ A S Sbjct: 94 --------VDEICKYRPENSVAQDT--GFTVVA-PGKEKALMKAVATVGPISVAMDAGHS 142 Query: 258 DFLTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNVDWGDNGFFKI 312 F YKSG+Y + + H + ++G+G E + YWLV NSW +WG NG+ KI Sbjct: 143 SFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDNSKYWLVKNSWGPEWGSNGYVKI 202 Query: 313 LRGE-NHCGIES 323 + + NHCGI + Sbjct: 203 AKDKNNHCGIAT 214 >1AEC-A nrPDB Length = 218 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 109/249 (43%), Gaps = 44/249 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D W + + I+ QG CG CWAF A+ + I T V + +S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTG--VLISLSEQELI 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GCNGGY + + F +++ G N+ PYT E +V+ Sbjct: 55 DCGRTQNTRGCNGGYITDGFQF-----IINNGGINTEEN-YPYTAQDGECNVD------- 101 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 + +K+ +Y +V + + + PV A D Sbjct: 102 -------------------LQNEKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--- 314 F Y SG++ G + HA+ I+G+G E G+ YW+V NSW+ WG+ G+ +ILR Sbjct: 143 AFKQYSSGIFTGPCGTAID-HAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GENHCGIES 323 G CGI + Sbjct: 202 GAGTCGIAT 210 >3HWN-A nrPDB Length = 258 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/250 (28%), Positives = 113/250 (45%), Gaps = 45/250 (18%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D RE+ P +++QG CGSCWAF A A+ ++ T GR+ + +S ++L+ Sbjct: 40 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKT-GRL-ISLSEQNLVD 93 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C G Q +GCNGG A+ + +GG+ + T C+++ Sbjct: 94 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYN---------- 139 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 259 PK + +AG+ + EK +M + GP+ A F Sbjct: 140 ----PKYSVANDAGF--------------VDIPKQEKALMKAVATVGPISVAIDAGHESF 181 Query: 260 LTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNVDWGDNGFFKILR 314 L YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ + Sbjct: 182 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAK 241 Query: 315 G-ENHCGIES 323 NHCGI S Sbjct: 242 DRRNHCGIAS 251 >4QRX-A nrPDB Length = 363 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 84/293 (28%), Positives = 129/293 (44%), Gaps = 54/293 (18%) Query: 31 INYINKQNTTWQAGRNFYNVDIS---YLKKLCGTVLGGPNLPERVGFSE-----DINLPE 82 I+ NK+N ++ G N + D+S + +K G++ G E + + E D+N+PE Sbjct: 97 IDETNKKNNSYWLGLNVF-ADMSNDEFKEKYTGSIAGNYTTTE-LSYEEVLNDGDVNIPE 154 Query: 83 SFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCC 142 D R++ + P +++QGSCGS WAF AV + I I T G +N E S ++LL C Sbjct: 155 YVDWRQKGAVTP----VKNQGSCGSAWAFSAVSTIESIIKIRT-GNLN-EYSEQELLDCD 208 Query: 143 GIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEG 202 + GCNGGYP A + G+ Y PY G + C Sbjct: 209 --RRSYGCNGGYPWSALQLVAQYGIHYRNTY-------PY---------EGVQRYCRSRE 250 Query: 203 DTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTY 262 P K Y E G YS+++ ++ E DF Y Sbjct: 251 KGPYAAKTDGVRQVQPYNE----GALLYSIANQPVSVVLE-----------AAGKDFQLY 295 Query: 263 KSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 + G++ G+ + HA+ +G+G Y L+ NSW WG+NG+ +I RG Sbjct: 296 RGGIFVGPCGNKV-DHAVAAVGYGPN----YILIRNSWGTGWGENGYIRIKRG 343 >5JA7-A nrPDB Length = 223 Score = 87.8 bits (216), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 118/257 (45%), Gaps = 50/257 (19%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P+S D R++ P +++QG CGS WAF +V A+ ++ T +N+ S ++L+ Sbjct: 10 PDSVDYRKKGYVTP----VKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNL--SPQNLVD 63 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYT--IPPCEHHVNGSRPP 197 C + DGC GGY + A+ + + +G+ S Y PY C ++ G Sbjct: 64 C--VSENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQEESCMYNPTGKAAK 114 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-F 256 C G + P+ N EK + + + GPV A Sbjct: 115 CRGYREIPEGN---------------------------EKALKRAVARVGPVSVAIDASL 147 Query: 257 SDFLTYKSGVYKHEAGDVMG-GHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 + F Y GVY E+ + HA+ +G+GI+ G +W++ NSW +WG+ G+ + R Sbjct: 148 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 207 Query: 316 ENH-CGIESEIVAGIPR 331 +N+ CGI + +A P+ Sbjct: 208 KNNACGIAN--LASFPK 222 >6MIS-A nrPDB Length = 215 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 65/238 (27%), Positives = 108/238 (45%), Gaps = 47/238 (19%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVN-VEVSAEDL 138 +P+S D W + + +++QG CGSCWAF ++ + I+ R N V +S + + Sbjct: 1 VPQSID----WRDSGAVTSVKNQGRCGSCWAFASIATVES---IYKIKRGNLVSLSEQQV 53 Query: 139 LTCCGIQCGDGCNGGYPSGAWNF-WTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 L C GC GG+ + A++F + KG+ S +Y P Sbjct: 54 LDCA---VSYGCKGGWINKAYSFIISNKGVASAAIY-----------------------P 87 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 T K N + + Y T Y +Y ++E+ +M + N P+ A Sbjct: 88 YKAAKGTCKTNGVPNSAYITRY---------TYVQRNNERNMMYAV-SNQPIAAALDASG 137 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIE-NGVPYWLVANSWNVDWGDNGFFKILR 314 +F YK GV+ G + HAI I+G+G + +G +W+V NSW WG+ G+ ++ R Sbjct: 138 NFQHYKRGVFTGPCGTRL-NHAIVIIGYGQDSSGKKFWIVRNSWGAGWGEGGYIRLAR 194 >5JT8-A nrPDB Length = 333 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 77/261 (29%), Positives = 115/261 (44%), Gaps = 56/261 (21%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 +LP++FD W + +IR QGSCGSCWAF A I + ++E+S ++L Sbjct: 112 SLPQNFD----WRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQK--QQSIELSEQEL 165 Query: 139 LTCC------GIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPP--CEHH 190 + C QC +GC GY + A+ + R GLV Y PY + C+ Sbjct: 166 VDCTYNRYDPSYQC-NGCGSGYSTEAFKYMIRTGLVEERNY-------PYNMRTQWCDPD 217 Query: 191 VNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPV- 249 V G R Y S GY S++++M I ++GPV Sbjct: 218 VEGQR-------------------YHVS-------GYQQLRYHSSDEDVMYTIQQHGPVV 251 Query: 250 ---EGAFTVFSDFLTYKSGVYKHEA-GDVMGGHAIRILGWGIENGVPYWLVANSWNVDWG 305 G+ F + +GV + A D HA+ ++GWG GV YW++ NSW WG Sbjct: 252 IYMHGSNNYFRNL---GNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWG 308 Query: 306 DNGFFKILRGENHCGIESEIV 326 + G+ + RG N GI + + Sbjct: 309 NGGYGYVERGHNSLGINNYVT 329 >1CJL-A nrPDB Length = 312 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 80/309 (25%), Positives = 133/309 (43%), Gaps = 54/309 (17%) Query: 31 INYINKQNTTWQAGRNFYNVDISYLKKLCGTVL-----GGPNLPERVG--FSEDI--NLP 81 + I N ++ G++ + + ++ + G N R G F E + P Sbjct: 35 MKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEAP 94 Query: 82 ESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTC 141 S D RE+ P +++QG CGS WAF A A+ ++ T GR+ + +S ++L+ C Sbjct: 95 RSVDWREKGYVTP----VKNQGQCGSSWAFSATGALEGQMFRKT-GRL-ISLSEQNLVDC 148 Query: 142 CGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGE 201 G + +GCNGG A+ + +GG+ + T C+++ Sbjct: 149 SGPEGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYN----------- 193 Query: 202 GDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDFL 260 PK + +AG+ + EK +M + GP+ A FL Sbjct: 194 ---PKYSVANDAGF--------------VDIPKQEKALMKAVATVGPISVAIDAGHESFL 236 Query: 261 TYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNVDWGDNGFFKILRG 315 YK G+Y + + H + ++G+G E +G YWLV NSW +WG G+ K+ + Sbjct: 237 FYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKD 296 Query: 316 -ENHCGIES 323 NHCGI S Sbjct: 297 RRNHCGIAS 305 >2ACT-A nrPDB Length = 220 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 114/249 (45%), Gaps = 44/249 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D W + + I+ QG CG CWAF A+ A + I T+G + + +S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAI-ATVEGINKITSGSL-ISLSEQELI 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GC+GGY + + F +++ G N+ PYT Sbjct: 55 DCGRTQNTRGCDGGYITDGFQF-----IINDGGINTEEN-YPYTAQ-------------- 94 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 +GD C+ + ++ K+ +Y +V + + + PV A D Sbjct: 95 -DGD-------CDV----ALQDQKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--- 314 F Y SG++ G + HAI I+G+G E GV YW+V NSW+ WG+ G+ +ILR Sbjct: 143 AFKQYASGIFTGPCGTAVD-HAIVIVGYGTEGGVDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GENHCGIES 323 G CGI + Sbjct: 202 GAGTCGIAT 210 >1EF7-A nrPDB Length = 242 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 49/249 (19%) Query: 80 LPESFDAREQWSNCPTI---AQIRDQ---GSCGSCWAFGAVEAMSDRICIHTNGR-VNVE 132 LP+S+D W N + + R+Q CGSCWA + AM+DRI I G + Sbjct: 1 LPKSWD----WRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTL 56 Query: 133 VSAEDLLTCCGIQCGDG--CNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHH 190 +S +++ I CG+ C GG W++ + G+ C ++ Sbjct: 57 LSVQNV-----IDCGNAGSCEGGNDLSVWDYAHQHGIPD---------------ETCNNY 96 Query: 191 VNGSRPPCTGEGDTPKCNKMCEAGYSTSYKE-DKHYGYTSYSVSD-----SEKEIMAEIY 244 + +C+K + G +KE YT + V D +++MAEIY Sbjct: 97 ----------QAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIY 146 Query: 245 KNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDW 304 NGP+ Y G+Y H + + GWGI +G YW+V NSW W Sbjct: 147 ANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPW 206 Query: 305 GDNGFFKIL 313 G+ G+ +I+ Sbjct: 207 GERGWLRIV 215 >2VHS-A nrPDB Length = 217 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 108/247 (43%), Gaps = 42/247 (17%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D RE+ P +++QG CG+ +AF A A+ ++ T GR+ + +S ++L+ Sbjct: 2 PRSVDWREKGYVTP----VKNQGQCGASYAFSATGALEGQMFRKT-GRL-ISLSEQNLVD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C G Q +GCNGG A+ + +GG+ + T C+++ S G Sbjct: 56 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDVG 111 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 259 D PK EK +M + GP+ A F Sbjct: 112 FVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHESF 143 Query: 260 LTYKSGVYKHEAGDVMG-GHAIRILGWG-IENGVPYWLVANSWNVDWGDNGFFKILRG-E 316 L YK G+Y HA+ ++G+G I N YWLV NSW +WG G+ K+ + Sbjct: 144 LFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKYWLVKNSWGEEWGMGGYVKMAKDRR 203 Query: 317 NHCGIES 323 NHCGI S Sbjct: 204 NHCGIAS 210 >3P5W-A nrPDB Length = 220 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 67/250 (26%), Positives = 111/250 (44%), Gaps = 44/250 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+ D W + + I+DQG CGSCWAF + A+ I T +++ S ++L+ Sbjct: 1 LPDYVD----WRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISL--SEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GC+GG+ + + F +++ G N+ PYT Sbjct: 55 DCGRTQNTRGCDGGFMTDGFQF-----IINNGGINTEAN-YPYT---------------- 92 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSEKEIMAEIYKNGPVEGAFTVFS- 257 + +CN +++K+ +Y +V + + + PV A Sbjct: 93 --AEEGQCN--------LDLQQEKYVSIDTYENVPYNNEWALQTAVAYQPVSVALEAAGY 142 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--- 314 +F Y SG++ G + HA+ I+G+G E G+ YW+V NSW WG+ G+ +I R Sbjct: 143 NFQHYSSGIFTGPCGTAVD-HAVTIVGYGTEGGIDYWIVKNSWGTTWGEEGYMRIQRNVG 201 Query: 315 GENHCGIESE 324 G CGI + Sbjct: 202 GVGQCGIAKK 211 >4YYR-A nrPDB Length = 222 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 108/258 (41%), Gaps = 43/258 (16%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R Q + P IR+QG CGSCWAF V + I T+ ++ S + L+ Sbjct: 1 LPETVDWRIQGAVNP----IRNQGRCGSCWAFSVVVVVEGITKIVTDELPSL--SEQQLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC+GG+ + A+++ + G ++ PYT E Sbjct: 55 DCATSYKNLGCSGGWMTKAYDYIIKNGGITSQ------SNYPYTAKKGE----------- 97 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-SD 258 CNK + + +H V + + + N PV Sbjct: 98 -------CNKDLASQIVATIDSYEH-------VPRNNENALKNAVANQPVSVTIEAGGRA 143 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG--- 315 F YKSGV+ G + HA+ +G+G EN V YWLV NSW +WG+ G+ K+ R Sbjct: 144 FELYKSGVFVGSCGTKLD-HAVVAIGYGSENDVDYWLVRNSWGTNWGERGYIKLQRNVAE 202 Query: 316 -ENHCGIESEIVAGIPRT 332 CGI + + +T Sbjct: 203 PTGKCGIAMQSTYPVKKT 220 >6EXO-A nrPDB Length = 215 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 64/249 (25%), Positives = 112/249 (44%), Gaps = 37/249 (14%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P + D RE+ + P ++DQG CGSCWAF + + + + N V++ S + L++ Sbjct: 2 PAAVDWREKGAVTP----VKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSL--SEQMLVS 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C I G C GG A+N+ + NS+ G + S P +G Sbjct: 56 CDTIDFG--CGGGLMDNAFNW----------IVNSNGGNV---------FTEASYPYVSG 94 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFL 260 G+ P+C G+ H + E I A + +NGP+ A S F+ Sbjct: 95 NGEQPQCQM---NGHEIGAAITDHV-----DLPQDEDAIAAYLAENGPLAIAVDATS-FM 145 Query: 261 TYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCG 320 Y G+ + + H + ++G+ + PYW++ NSW+ WG++G+ +I +G N C Sbjct: 146 DYNGGILTSCTSEQLD-HGVLLVGYNDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCL 204 Query: 321 IESEIVAGI 329 + + + + Sbjct: 205 MNQAVSSAV 213 >6BKI-A nrPDB Length = 215 Score = 81.3 bits (199), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 63/255 (24%), Positives = 114/255 (44%), Gaps = 44/255 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P+S D R++ P +++QG CGSCWAF + A+ ++ T G++ + +S ++L+ Sbjct: 1 VPDSIDYRKKGYVTP----VKNQGQCGSCWAFSSAGALEGQLKKKT-GKL-LALSPQNLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GGY + A+ + + G + ++G C ++ C Sbjct: 55 DC--VTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVG----QDESCMYNAAAKAAKCR 108 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSD 258 G + P N EK + + + GP+ + + Sbjct: 109 GYREIPVGN---------------------------EKALKRAVARVGPISVSIDASLAS 141 Query: 259 FLTYKSGVYKHEAGDVMG-GHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 F Y GVY E D HA+ ++G+G + G +W++ NSW WG+ G+ + R +N Sbjct: 142 FQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKN 201 Query: 318 H-CGIESEIVAGIPR 331 + CGI + +A P+ Sbjct: 202 NACGITN--MASFPK 214 >1S4V-A nrPDB Length = 229 Score = 80.9 bits (198), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 71/259 (27%), Positives = 107/259 (41%), Gaps = 45/259 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P S D W + ++DQG CGSCWAF + A+ I TN V++ +E L Sbjct: 2 VPASVD----WRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSL---SEQEL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GCNGG A+ F ++G ++ N Sbjct: 55 VDCDTDQNQGCNGGLMDYAFEFIKQRGGIT-------------------TEANYPYEAYD 95 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-SD 258 G D K N + + D H +V ++++ + + N PV A SD Sbjct: 96 GTCDVSKEN-------APAVSIDGHE-----NVPENDENALLKAVANQPVSVAIDAGGSD 143 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIE-NGVPYWLVANSWNVDWGDNGFFKILRG-- 315 F Y GV+ G + H + I+G+G +G YW V NSW +WG+ G+ ++ RG Sbjct: 144 FQFYSEGVFTGSCGTELD-HGVAIVGYGTTIDGTKYWTVKNSWGPEWGEKGYIRMERGIS 202 Query: 316 --ENHCGIESEIVAGIPRT 332 E CGI E I ++ Sbjct: 203 DKEGLCGIAMEASYPIKKS 221 >3QT4-A nrPDB Length = 329 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 74/334 (22%), Positives = 135/334 (40%), Gaps = 55/334 (16%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNV------DISYLK 56 WS L+ + +S ++ + D + I + N ++ G Y+ D+S + Sbjct: 27 WSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQFGDMSKEE 86 Query: 57 KLCGTVLGGPNLPERVGFSEDINLP-----ESFDAREQWSNCPTIAQIRDQGSCGSCWAF 111 L G P+ E++ +P + A W +++++DQG CGS W+F Sbjct: 87 FLAYVNRGKAQKPKH---PENLRMPYVSSKKPLAASVDW-RSNAVSEVKDQGQCGSSWSF 142 Query: 112 GAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGG 171 A+ ++ + GR+ +S ++L+ C GC+GG+ A+++ G++S Sbjct: 143 STTGAVEGQLALQ-RGRL-TSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDYGIMSES 200 Query: 172 VYNSHIGCLPYTIPP--CEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTS 229 Y PY C + S +G D P Sbjct: 201 AY-------PYEAQGDYCRFDSSQSVTTLSGYYDLP------------------------ 229 Query: 230 YSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGV-YKHEAGDVMGGHAIRILGWGIE 288 S E + + + GPV A + Y G+ Y H + ++G+G + Sbjct: 230 ---SGDENSLADAVGQAGPVAVAIDATDELQFYSGGLFYDQTCNQSDLNHGVLVVGYGSD 286 Query: 289 NGVPYWLVANSWNVDWGDNGFFKILRGE-NHCGI 321 NG YW++ NSW WG++G+++ +R N+CGI Sbjct: 287 NGQDYWILKNSWGSGWGESGYWRQVRNYGNNCGI 320 >2CIO-A nrPDB Length = 212 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 69/236 (29%), Positives = 102/236 (43%), Gaps = 44/236 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +PE D R++ + P +++QGSCGSCWAF AV + I I T G +N + S ++LL Sbjct: 1 IPEYVDWRQKGAVTP----VKNQGSCGSCWAFSAVVTIEGIIKIRT-GNLN-QYSEQELL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GCNGGYP A + G+ Y PY G + C Sbjct: 55 DC--DRRSYGCNGGYPWSALQLVAQYGIHYRNTY-------PY---------EGVQRYCR 96 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 P K Y E G YS+++ ++ E DF Sbjct: 97 SREKGPYAAKTDGVRQVQPYNE----GALLYSIANQPVSVVLE-----------AAGKDF 141 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 Y+ G++ G+ + HA+ +G+G Y L+ NSW WG+NG+ +I RG Sbjct: 142 QLYRGGIFVGPCGNKV-DHAVAAVGYGPN----YILIKNSWGTGWGENGYIRIKRG 192 >1CQD-A nrPDB Length = 221 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 109/250 (43%), Gaps = 50/250 (20%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 +LP+S D RE + P +++QG CGSCWAF V A+ I T +++ S + L Sbjct: 2 DLPDSIDWRENGAVVP----VKNQGGCGSCWAFSTVAAVEGINQIVTGDLISL--SEQQL 55 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C GC GG+ + A+ F +V+ G NS PY Sbjct: 56 VDC--TTANHGCRGGWMNPAFQF-----IVNNGGINSE-ETYPY---------------- 91 Query: 199 TGEGDTPKCNKMCEAGYST--SYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 G CN A + SY+ +V ++ + + N PV Sbjct: 92 --RGQDGICNSTVNAPVVSIDSYE----------NVPSHNEQSLQKAVANQPVSVTMDAA 139 Query: 257 -SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 DF Y+SG++ ++ HA+ ++G+G EN +W+V NSW +WG++G+ + R Sbjct: 140 GRDFQLYRSGIFTGSC-NISANHALTVVGYGTENDKDFWIVKNSWGKNWGESGYIRAERN 198 Query: 316 ----ENHCGI 321 + CGI Sbjct: 199 IENPDGKCGI 208 >2FO5-A nrPDB Length = 262 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/253 (26%), Positives = 102/253 (40%), Gaps = 44/253 (17%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 +LP S D W + ++DQG CGSCWAF V ++ I T V++ +E Sbjct: 3 DLPPSVD----WRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSL---SEQE 55 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKG-LVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 L C DGC GG A+ + G L++ Y PY G+ Sbjct: 56 LIDCDTADNDGCQGGLMDNAFEYIKNNGGLITEAAY-------PY------RAARGTCNV 102 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 ++P + D H V + +E +A N PV A Sbjct: 103 ARAAQNSPVVVHI-----------DGHQ-----DVPANSEEDLARAVANQPVSVAVEASG 146 Query: 258 D-FLTYKSGVYKHEAGDVMGGHAIRILGWGI-ENGVPYWLVANSWNVDWGDNGFFKILRG 315 F+ Y GV+ E G + H + ++G+G+ E+G YW V NSW WG+ G+ ++ + Sbjct: 147 KAFMFYSEGVFTGECGTELD-HGVAVVGYGVAEDGKAYWTVKNSWGPSWGEQGYIRVEKD 205 Query: 316 ENH----CGIESE 324 CGI E Sbjct: 206 SGASGGLCGIAME 218 >4YYQ-A nrPDB Length = 217 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 72/237 (30%), Positives = 104/237 (43%), Gaps = 43/237 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D W + + IR+QG CGSCWAF AV A+ I T + +S + LL Sbjct: 1 LPETVD----WRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTG--QLLSLSEQQLL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 C GC GG+ + A+ + + +G+ S Y P Sbjct: 55 DCAQSYKNLGCQGGWVNKAFEYIIQNRGITSQSNY-----------------------PY 91 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 TG C G ++ D + Y S++E + + N PV A Sbjct: 92 TGH------KGQCRTGLASIATIDSY----QYVPSNNENALKNAV-ANQPVSVAVEAAGR 140 Query: 259 -FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 F YKSGV+ G V HA+ ++G+G NGV YWL+ NSW +WG+ G+ K+ R Sbjct: 141 AFQLYKSGVFTGSCG-VAIDHAVVLIGYGKYNGVDYWLLRNSWGTNWGEQGYMKLQR 196 >4OEL-A nrPDB Length = 370 Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 38/196 (19%) Query: 78 INLPESFDAREQWSNCPTI---AQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVS 134 ++LP S+D W N I + +R+Q SCGSC++F ++ + RI I TN +S Sbjct: 205 LHLPTSWD----WRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILS 260 Query: 135 AEDLLTCCGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 +++++C Q GC GG+P A + GLV C PYT G Sbjct: 261 PQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEE-------ACFPYT---------G 302 Query: 194 SRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 253 + PC + D C YS+ Y HY Y + E + E+ +GP+ AF Sbjct: 303 TDSPCKMKED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAF 350 Query: 254 TVFSDFLTYKSGVYKH 269 V+ DFL YK G+Y H Sbjct: 351 EVYDDFLHYKKGIYHH 366 >5VPK-A nrPDB Length = 223 Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 61/252 (24%), Positives = 97/252 (38%), Gaps = 50/252 (19%) Query: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 +N+P D R + T+ IR QG CGSCWAF V A + N ++++S ++ Sbjct: 9 VNVPSELDLR----SLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRN--TSLDLSEQE 62 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 L+ C GC+G + + G+V Y PY Sbjct: 63 LVDCAS---QHGCHGDTIPRGIEYIQQNGVVEERSY-------PYV-------------- 98 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYS--VSDSEKEIMAEIYKNGPVEGAFTV 255 +C + +HYG ++Y K+I + + Sbjct: 99 ----AREQQCRR----------PNSQHYGISNYCQIYPPDVKQIREALTQTHTAIAVIIG 144 Query: 256 FSDFLTYK----SGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFK 311 D ++ + +H+ G HA+ I+G+G GV YW+V NSW+ WGD+G+ Sbjct: 145 IKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGVDYWIVRNSWDTTWGDSGYGY 204 Query: 312 ILRGENHCGIES 323 G N IE Sbjct: 205 FQAGNNLMMIEQ 216 >4CDF-B nrPDB Length = 166 Score = 73.9 bits (180), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 62/196 (31%), Positives = 91/196 (46%), Gaps = 38/196 (19%) Query: 78 INLPESFDAREQWSNCPTI---AQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVS 134 ++LP S+D W N I + +R+Q SCGSC++F ++ + RI I TN +S Sbjct: 1 LHLPTSWD----WRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILS 56 Query: 135 AEDLLTCCGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 +++++C Q GC GG+P A + GLV C PYT G Sbjct: 57 PQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEE-------ACFPYT---------G 98 Query: 194 SRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 253 + PC + D C YS+ Y HY Y + E + E+ +GP+ AF Sbjct: 99 TDSPCKMKED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAF 146 Query: 254 TVFSDFLTYKSGVYKH 269 V+ DFL YK G+Y H Sbjct: 147 EVYDDFLHYKKGIYHH 162 >3BPF-A nrPDB Length = 241 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 73/270 (27%), Positives = 119/270 (44%), Gaps = 61/270 (22%) Query: 82 ESFD-AREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 E+FD A W + ++DQ +CGSCWAF ++ ++ + I N + + S ++L+ Sbjct: 15 ENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITL--SEQELVD 72 Query: 141 CCGIQCGDGCNGGYPSGAW-NFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C G CNGG + A+ + G+ G Y PY Sbjct: 73 CSFKNYG--CNGGLINNAFEDMIELGGICPDGDY-------PYV---------------- 107 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSE-KEIMAEIYKNGPVEGAFTVFS 257 D P +C T + YG +Y SV D++ KE + + GP+ + V Sbjct: 108 --SDAPN---LCNIDRCT-----EKYGIKNYLSVPDNKLKEALRFL---GPISISVAVSD 154 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVP----------YWLVANSWNVDWGDN 307 DF YK G++ E GD + HA+ ++G+G++ V Y+++ NSW WG+ Sbjct: 155 DFAFYKEGIFDGECGDQLN-HAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGER 213 Query: 308 GFFKILRGEN----HCGIESEIVAGIPRTQ 333 GF I E+ CG+ ++ A IP + Sbjct: 214 GFINIETDESGLMRKCGLGTD--AFIPLIE 241 >5EF4-A nrPDB Length = 385 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 71/282 (25%), Positives = 116/282 (41%), Gaps = 48/282 (17%) Query: 47 FYNVDISYLKKLCGTVLGGPNLPERVGF--SEDINLPESFDAREQWSNCPTIAQIRDQGS 104 + N IS+ + L G+ G + F + +P+ D RE+ + + ++ QG Sbjct: 95 YANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDWREKNA----VTDVKGQGG 150 Query: 105 CGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTR 164 CGSCWAF AV A+ I T G++ V+ S + L+ C GC+GG A+ + + Sbjct: 151 CGSCWAFAAVVALEGINAIRT-GKL-VKFSEQQLVDCDMTNA--GCDGGLMEPAFTYVIK 206 Query: 165 KGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKH 224 G ++ P + G R C D K + + Sbjct: 207 HGGIA---------------PEASYPYVGKRETC----DKAKIKDVLKID---------- 237 Query: 225 YGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLT-YKSGVYKHEAGDVMGGHAIRIL 283 +V ++E + + + PV + L Y GVY + G H + I+ Sbjct: 238 ---GRQNVPGLDEEALRKAVAHQPVATGIQLSGHGLQFYSEGVYTGDCG-TEPNHGVGIV 293 Query: 284 GWGI-ENGVPYWLVANSWNVDWGDNGFFKILRG---ENHCGI 321 G+G E G+ +W V NSW WG+ G+ + RG E CG+ Sbjct: 294 GYGENEKGIKFWTVKNSWGPTWGEKGYIHLQRGARKEGLCGV 335 >1M6D-A nrPDB Length = 214 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 59/243 (24%), Positives = 103/243 (42%), Gaps = 40/243 (16%) Query: 90 WSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDG 149 W + + +++DQG CGSCWAF + + + N + +S ++LL C + Sbjct: 7 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL--NQGTLLSLSEQELLDCDKMD--KA 62 Query: 150 CNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNK 209 C GG PS A+ S I L ++ G C Sbjct: 63 CMGGLPSNAY---------------SAIKNLGGLETEDDYSYQGHMQSC----------- 96 Query: 210 MCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGV--- 266 S ++ K Y S +S +E+++ A + K GP+ A F Y+ G+ Sbjct: 97 ------QFSAEKAKVYIQDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 149 Query: 267 YKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIV 326 + + HA+ ++G+G + VP+W + NSW DWG+ G++ + RG CG+ + Sbjct: 150 LRPLCSPWLIDHAVLLVGYGQRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMAS 209 Query: 327 AGI 329 + + Sbjct: 210 SAV 212 >1PCI-A nrPDB Length = 322 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 83/299 (27%), Positives = 131/299 (43%), Gaps = 56/299 (18%) Query: 29 DMINYI---NKQNTTWQAGRNFYNVDIS---YLKKLCGTVLGG---PNLPERVGFSEDIN 79 D +NYI NK+N ++ G N + D+S + +K G+++ + E + +N Sbjct: 48 DNLNYIDETNKKNNSYWLGLNEF-ADLSNDEFNEKYVGSLIDATIEQSYDEEFINEDIVN 106 Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R++ + P +R QGSCGSCWAF AV + I T G++ VE+S ++L+ Sbjct: 107 LPENVDWRKKGAVTP----VRHQGSCGSCWAFSAVATVEGINKIRT-GKL-VELSEQELV 160 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPP--CE-HHVNGSRP 196 C + GC GGYP A + + G+ Y PY C V G Sbjct: 161 DCE--RRSHGCKGGYPPYALEYVAKNGIHLRSKY-------PYKAKQGTCRAKQVGGPIV 211 Query: 197 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 +G G N+ G +++ ++ E K P Sbjct: 212 KTSGVGRVQPNNE----------------GNLLNAIAKQPVSVVVE-SKGRP-------- 246 Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 F YK G+++ G + G A+ +G+G G Y L+ NSW WG+ G+ +I R Sbjct: 247 --FQLYKGGIFEGPCGTKVDG-AVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRA 302 >1YAL-A nrPDB Length = 218 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 61/245 (24%), Positives = 105/245 (42%), Gaps = 44/245 (17%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P+S D R + + P +++QG+CGSCWAF + + I T + E+S ++L+ Sbjct: 2 PQSIDWRAKGAVTP----VKNQGACGSCWAFSTIATVEGINKIVTGNLL--ELSEQELVD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C + GC GGY + + + G+ + VY PY ++ + P Sbjct: 56 C--DKHSYGCKGGYQTTSLQYVANNGVHTSKVY-------PYQAK--QYKCRATDKP--- 101 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFL 260 PK T YK TS+ + + + + + G F Sbjct: 102 ---GPKVK-------ITGYKRVPSNCETSFLGALANQPLSVLVEAGG---------KPFQ 142 Query: 261 TYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR----GE 316 YKSGV+ G + HA+ +G+G +G Y ++ NSW +WG+ G+ ++ R + Sbjct: 143 LYKSGVFDGPCGTKLD-HAVTAVGYGTSDGKNYIIIKNSWGPNWGEKGYMRLKRQSGNSQ 201 Query: 317 NHCGI 321 CG+ Sbjct: 202 GTCGV 206 >5A24-A nrPDB Length = 222 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/246 (26%), Positives = 99/246 (40%), Gaps = 39/246 (15%) Query: 86 AREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQ 145 A W + +++Q CG CWAF AV A+ I T + +S E ++ C Sbjct: 3 AAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTS--LSEEQIVDCDTNG 60 Query: 146 CGDGCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDT 204 GCNGG P GA+ + +G+ + Y PYT GS C+ Sbjct: 61 NDKGCNGGTPDGAFQYVVNNQGIDTESDY-------PYTAG------GGSPGTCSASSYQ 107 Query: 205 PKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKS 264 P A T Y++ + + + + I I + P F +Y S Sbjct: 108 P-------AASITGYQDVPANNEQALQQAAATQPISVAIDASDP---------SFQSYSS 151 Query: 265 GVYKHEAGDVMGGHAIRILGWGIE--NGVPYWLVANSWNVDWGDNGFFKILRGENH---- 318 G+Y + HA+ ++G+G + +G YW+V NSW WG G+ + G N Sbjct: 152 GIYSGPCNTNL-DHAVTVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGV 210 Query: 319 CGIESE 324 CGI + Sbjct: 211 CGIAMQ 216 >3BPM-A nrPDB Length = 243 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 95/232 (40%), Gaps = 48/232 (20%) Query: 96 IAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYP 155 + ++DQ CGSCWAF +V ++ + I + + +E L C ++ +GC GGY Sbjct: 32 VTPVKDQALCGSCWAFSSVGSVESQYAIRKKA---LFLFSEQELVDCSVK-NNGCYGGYI 87 Query: 156 SGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGY 215 + A++ G + ++ LP T + +CN+ Sbjct: 88 TNAFDDMIDLGGLCSQDDYPYVSNLPETC------------------NLKRCNERYTIKS 129 Query: 216 STSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVM 275 S +DK KE + + GP+ + DF Y+ G Y E G Sbjct: 130 YVSIPDDKF------------KEALRYL---GPISISIAASDDFAFYRGGFYDGECG-AA 173 Query: 276 GGHAIRILGWGIEN----------GVPYWLVANSWNVDWGDNGFFKILRGEN 317 HA+ ++G+G+++ Y+++ NSW DWG+ G+ + EN Sbjct: 174 PNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDEN 225 >5VCN-A nrPDB Length = 222 Score = 63.9 bits (154), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 85/232 (36%), Gaps = 40/232 (17%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 N P D R+ T+ IR QG CGSCWAF V A + N +++ AE Sbjct: 9 NAPAEIDLRQM----RTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDL---AEQE 61 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 L C Q GC+G + G+V Y C Sbjct: 62 LVDCASQ--HGCHGDTIPRGIEYIQHNGVVQESYY----------------RYVAREQSC 103 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 P + + Y Y + ++ +E +A+ + V Sbjct: 104 R----RPNAQRFGISNYCQIYPPN----------ANKIREALAQTHSAIAVIIGIKDLDA 149 Query: 259 FLTYK-SGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGF 309 F Y + + + G HA+ I+G+ GV YW+V NSW+ +WGDNG+ Sbjct: 150 FRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGY 201 >2BDZ-A nrPDB Length = 214 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 69/250 (27%), Positives = 106/250 (42%), Gaps = 58/250 (23%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 PES D RE+ + P +++Q CGSCWAF V A + I G++ + +S ++LL Sbjct: 2 PESIDWREKGAVTP----VKNQNPCGSCWAFSTV-ATIEGINKIITGQL-ISLSEQELLD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C + GC+GGY + + + +V GV H P Sbjct: 56 C--ERRSHGCDGGYQTTSLQY-----VVDNGV-----------------HTEREYPYEKK 91 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD-- 258 +G +K Y T YK Y ++ E ++ I N PV +V +D Sbjct: 92 QGRCRAKDKKGPKVYITGYK---------YVPANDEISLIQAI-ANQPV----SVVTDSR 137 Query: 259 ---FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 F YK G+Y+ G HA+ +G+ G Y L+ NSW +WG+ G+ +I R Sbjct: 138 GRGFQFYKGGIYEGPCG-TNTDHAVTAVGY----GKTYLLLKNSWGPNWGEKGYIRIKRA 192 Query: 316 ENH----CGI 321 CG+ Sbjct: 193 SGRSKGTCGV 202 >1IWD-A nrPDB Length = 215 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 61/235 (25%), Positives = 100/235 (42%), Gaps = 41/235 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D W + + I++Q CGSCWAF AV A+ I T G++ + +S ++L+ Sbjct: 1 LPSFVD----WRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRT-GQL-ISLSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GCNGG+ + A+ + + +GG+ PY+ V GS P Sbjct: 55 DC--DTASHGCNGGWMNNAFQYI----ITNGGIDTQQ--NYPYSA------VQGSCKP-- 98 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 Y + + + + + +A + VE A F Sbjct: 99 ---------------YRLRVVSINGFQRVTRNNESALQSAVASQPVSVTVEAAGAPFQH- 142 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 Y SG++ G H + I+G+G ++G YW+V NSW +WG+ G+ + R Sbjct: 143 --YSSGIFTGPCGTAQN-HGVVIVGYGTQSGKNYWIVRNSWGQNWGNQGYIWMER 194 >1ICF-A nrPDB Length = 175 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 40/211 (18%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D RE+ P +++QG CGSCWAF A A+ ++ GR+ + +S ++L+ Sbjct: 2 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQM-FRKTGRL-ISLSEQNLVD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C G Q +GCNGG A+ + +GG+ + T C+++ S TG Sbjct: 56 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDTG 111 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 259 D PK EK +M + GP+ A F Sbjct: 112 FVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHESF 143 Query: 260 LTYKSGVY-KHEAGDVMGGHAIRILGWGIEN 289 L YK G+Y + + H + ++G+G E+ Sbjct: 144 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 174 >1PPO-A nrPDB Length = 216 Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 102/235 (43%), Gaps = 40/235 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R++ + P +R QGSCGSCWAF AV + I T G++ VE+S ++L+ Sbjct: 1 LPENVDWRKKGAVTP----VRHQGSCGSCWAFSAVATVEGINKIRT-GKL-VELSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GGYP A + + G+ H+ S+ P Sbjct: 55 DC--ERRSHGCKGGYPPYALEYVAKNGI----------------------HLR-SKYPYK 89 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 + T + ++ TS ++E ++ I K + F Sbjct: 90 AKQGTCRAKQVGGPIVKTS--------GVGRVQPNNEGNLLNAIAKQPVSVVVESKGRPF 141 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 YK G+++ G + HA+ +G+G G Y L+ NSW WG+ G+ +I R Sbjct: 142 QLYKGGIFEGPCGTKV-DHAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKR 195 >1O0E-A nrPDB Length = 208 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 98/244 (40%), Gaps = 48/244 (19%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE D R++ + P +++QGSCGSCWAF V + I T ++ +S ++L+ Sbjct: 1 LPEQIDWRKKGAVTP----VKNQGSCGSCWAFSTVSTVESINQIRTGNLIS--LSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C D N G GA+ F + + +GG+ PY Sbjct: 55 DC------DKKNHGCLGGAFVFAYQYIINNGGIDTQ--ANYPYKAVQGPCQAASKVVSID 106 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 G P CN+ + K+ ++ ++ S + F Sbjct: 107 GYNGVPFCNE-------XALKQAVAVQPSTVAIDASSAQ--------------------F 139 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--GEN 317 Y SG++ G + H + I+G+ YW+V NSW WG+ G+ ++LR G Sbjct: 140 QQYSSGIFSGPCGTKL-NHGVTIVGYQAN----YWIVRNSWGRYWGEKGYIRMLRVGGCG 194 Query: 318 HCGI 321 CGI Sbjct: 195 LCGI 198 >3BCN-A nrPDB Length = 209 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 62/246 (25%), Positives = 96/246 (39%), Gaps = 52/246 (21%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE D R + + P +++QG CGSCWAF V + I T ++ +S + L+ Sbjct: 1 LPEHVDWRAKGAVIP----LKNQGKCGSCWAFSTVTTVESINQIRTGNLIS--LSEQQLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTI--PPCEHHVNGSRPP 197 C + GC GGY A+ + +++ G ++ PY PC R Sbjct: 55 DCS--KKNHGCKGGYFDRAYQY-----IIANGGIDTEAN-YPYKAFQGPCRAAKKVVR-- 104 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 G P+CN E + + V Sbjct: 105 IDGCKGVPQCN---------------------------ENALKNAVASQPSVVAIDASSK 137 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--G 315 F YK G++ G + H + I+G+G + YW+V NSW WG+ G+ ++ R G Sbjct: 138 QFQHYKGGIFTGPCGTKL-NHGVVIVGYGKD----YWIVRNSWGRHWGEQGYTRMKRVGG 192 Query: 316 ENHCGI 321 CGI Sbjct: 193 CGLCGI 198 >4OEM-B nrPDB Length = 70 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 26/58 (44%), Positives = 39/58 (67%), Gaps = 2/58 (3%) Query: 275 MGGHAIRILGWGIEN--GVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGIP 330 + HA+ ++G+G ++ G+ YW+V NSW WG+NG+F+I RG + C IES VA P Sbjct: 8 LTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATP 65 >1XKG-A nrPDB Length = 312 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 59/238 (24%), Positives = 90/238 (37%), Gaps = 52/238 (21%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 N P D R+ T+ IR QG CGS WAF V A + + +++ AE Sbjct: 89 NAPAEIDLRQ----MRTVTPIRMQGGCGSAWAFSGVAATESAYLAYRDQSLDL---AEQE 141 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 L C Q GC+G + G+V Y + RP Sbjct: 142 LVDCASQ--HGCHGDTIPRGIEYIQHNGVVQESYYRY-----------VAREQSCRRPNA 188 Query: 199 TGEGDT-------PKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEG 251 G + P NK+ EA T +++ +V K++ A + +G Sbjct: 189 QRFGISNYCQIYPPNANKIREALAQT---------HSAIAVIIGIKDLDAFRHYDGRT-- 237 Query: 252 AFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGF 309 + + + G HA+ I+G+ GV YW+V NSW+ +WGDNG+ Sbjct: 238 --------------IIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGY 281 >2B1M-A nrPDB Length = 246 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 62/240 (25%), Positives = 95/240 (39%), Gaps = 40/240 (16%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 + PES+D WS I +++ QG CGS WAF A A+ I T V++ S ++L Sbjct: 1 DAPESWD----WSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSL--SEQEL 54 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C + +GC G W++ + + +V G S PY + N + Sbjct: 55 IDC--VDESEGCYNG-----WHYQSFEWVVKHGGIASEAD-YPYKARDGKCKANEIQDKV 106 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 T + + SVS K D Sbjct: 107 TIDNYGVQILSNESTESEAESSLQSFVLEQPISVSIDAK--------------------D 146 Query: 259 FLTYKSGVYKHEAGDVMG----GHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 F Y G+Y + G+ H + I+G+G E+GV YW+ NSW DWG +G+ +I R Sbjct: 147 FHFYSGGIY--DGGNCSSPYGINHFVLIVGYGSEDGVDYWIAKNSWGEDWGIDGYIRIQR 204 >3F75-A nrPDB Length = 224 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 62/250 (24%), Positives = 99/250 (39%), Gaps = 45/250 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP A W + + ++DQ CGSCWAF A+ C T G++ V +S ++L+ Sbjct: 3 LPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKT-GKL-VSLSEQELM 60 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTI--PPCEHHVNGSRPP 197 C + C+GG + A+ + L SGG+ + PY C Sbjct: 61 DCSRAEGNQSCSGGEMNDAFQYV----LDSGGICSEDA--YPYLARDEECRAQSCEKVVK 114 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 G D P+ SE + A + K+ PV A Sbjct: 115 ILGFKDVPR---------------------------RSEAAMKAALAKS-PVSIAIEADQ 146 Query: 258 -DFLTYKSGVYKHEAGDVMGGHAIRILGWGI--ENGVPYWLVANSWNVDWGDNGFFKIL- 313 F Y GV+ G + H + ++G+G E+ +W++ NSW WG +G+ + Sbjct: 147 MPFQFYHEGVFDASCGTDL-DHGVLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYMYMAM 205 Query: 314 -RGEN-HCGI 321 +GE CG+ Sbjct: 206 HKGEEGQCGL 215 >3U8E-A nrPDB Length = 222 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 65/253 (25%), Positives = 105/253 (41%), Gaps = 52/253 (20%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D R++ + + ++DQG+CG CWAFGA A+ + I T GR+ + VS + ++ Sbjct: 2 PASIDWRKKGA----VTSVKDQGACGMCWAFGATGAI-EGIDAITTGRL-ISVSEQQIVD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C D G + R + +GG+ + + P TG Sbjct: 56 C------DTXXXXXXGGDADDAFRWVITNGGI------------------ASDANYPYTG 91 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFL 260 T NK A + GYT+ V +S ++ + K +T + F Sbjct: 92 VDGTCDLNKPIAA---------RIDGYTN--VPNSSSALLDAVAKQPVSVNIYTSSTSFQ 140 Query: 261 TYKS-GVYKHEA---GDVMGGHAIRILGWGIENGV--PYWLVANSWNVDWGDNGFFKILR 314 Y G++ + H + I+G+G NG YW+V NSW +WG +G+ I R Sbjct: 141 LYTGPGIFAGSSCSDDPATVDHTVLIVGYG-SNGTNADYWIVKNSWGTEWGIDGYILIRR 199 Query: 315 GENH----CGIES 323 N C I++ Sbjct: 200 NTNRPDGVCAIDA 212 >1GEC-E nrPDB Length = 216 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 106/259 (40%), Gaps = 50/259 (19%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPES D R + + P ++ QG C SCWAF V + I T V E+S ++L+ Sbjct: 1 LPESVDWRAKGAVTP----VKHQGYCESCWAFSTVATVEGINKIKTGNLV--ELSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPP--CE-HHVNGSRP 196 C +Q GCN GY S + + + G+ Y PY C + V G + Sbjct: 55 DC-DLQ-SYGCNRGYQSTSLQYVAQNGIHLRAKY-------PYIAKQQTCRANQVGGPKV 105 Query: 197 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 G G N+ G +++ ++ E + Sbjct: 106 KTNGVGRVQSNNE----------------GSLLNAIAHQPVSVVVE-----------SAG 138 Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE 316 DF YK G+++ G + HA+ +G+G G Y L+ NSW WG+NG+ +I R Sbjct: 139 RDFQNYKGGIFEGSCGTKVD-HAVTAVGYGKSGGKGYILIKNSWGPGWGENGYIRIRRAS 197 Query: 317 NHCGIESEIVAGIPRTQQY 335 + S V G+ R+ Y Sbjct: 198 GN----SPGVCGVYRSSYY 212 >2PNS-A nrPDB Length = 208 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/246 (24%), Positives = 94/246 (38%), Gaps = 52/246 (21%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE D R++ + P +++QG CGSCWAF V + I T ++ +S + L+ Sbjct: 1 LPEQIDWRKKGAVTP----VKNQGKCGSCWAFSTVSTVESINQIRTGNLIS--LSEQQLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIP--PCEHHVNGSRPP 197 C + GC GG A+ + ++ G ++ PY PC R Sbjct: 55 DCN--KKNHGCKGGAFVYAYQY-----IIDNGGIDTEAN-YPYKAVQGPCRAAKKVVR-- 104 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 G P CN E + + V Sbjct: 105 IDGYKGVPHCN---------------------------ENALKKAVASQPSVVAIDASSK 137 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--G 315 F YKSG++ G + H + I+G+ + YW+V NSW WG+ G+ ++ R G Sbjct: 138 QFQHYKSGIFSGPCGTKL-NHGVVIVGYWKD----YWIVRNSWGRYWGEQGYIRMKRVGG 192 Query: 316 ENHCGI 321 CGI Sbjct: 193 CGLCGI 198 >5I4H-B nrPDB Length = 112 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 232 VSDSEKEIMAEIYKNGPVEGAFTV-FSDFLTYKSGVY-KHEAGDVMGGHAIRILGWGIE- 288 + EK +M + GP+ A FL YK G+Y + + H + ++G+G E Sbjct: 7 IPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 66 Query: 289 ---NGVPYWLVANSWNVDWGDNGFFKILRG-ENHCGIES 323 + YWLV NSW +WG G+ K+ + NHCGI S Sbjct: 67 TESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 105 >5I4H-A nrPDB Length = 106 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 6/86 (6%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D RE+ P +++QG CGS WAF A A+ ++ GR+ + +S ++L+ Sbjct: 3 PRSVDWREKGYVTP----VKNQGQCGSSWAFSATGALEGQM-FRKTGRL-ISLSEQNLVD 56 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKG 166 C G Q +GCNGG A+ + G Sbjct: 57 CSGPQGNEGCNGGLMDYAFQYVQDNG 82 >3IOQ-A nrPDB Length = 213 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 59/254 (23%), Positives = 95/254 (37%), Gaps = 54/254 (21%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P S D R++ + P +R+QG CGSCW F +V A+ I T +++ Sbjct: 1 IPTSIDWRQKGAVTP----VRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDC 56 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPY--TIPPCE-HHVNGSRP 196 + GC GG+P A + G+ Y PY C G + Sbjct: 57 E----RRSYGCRGGFPLYALQYVANSGIHLRQYY-------PYEGVQRQCRASQAKGPKV 105 Query: 197 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 G G P+ N+ ++ I+ E Sbjct: 106 KTDGVGRVPRNNEQA----------------LIQRIAIQPVSIVVEAKGRA--------- 140 Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG- 315 F Y+ G++ G + HA+ +G+G + Y L+ NSW WG+ G+ +I RG Sbjct: 141 --FQNYRGGIFAGPCGTSI-DHAVAAVGYGND----YILIKNSWGTGWGEGGYIRIKRGS 193 Query: 316 ---ENHCGIESEIV 326 + CG+ S+ V Sbjct: 194 GNPQGACGVLSDSV 207 >3CH2-X nrPDB Length = 265 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 60/241 (24%), Positives = 96/241 (39%), Gaps = 22/241 (9%) Query: 91 SNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGC 150 +NC + Q+ DQG+C + W F + + C+ G ++SA + C + D C Sbjct: 16 NNCISNLQVEDQGNCDTSWIFASKYHLETIRCM--KGYEPTKISALYVANCYKGEHKDRC 73 Query: 151 N-GGYPSGAWNFWTRKGLV-SGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCN 208 + G P G + + Y + + P E H + + N Sbjct: 74 DEGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPN 133 Query: 209 KMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYK 268 + GY+ E H ++ K I E+ G V A+ + + Y+ K Sbjct: 134 SLDGKGYTAYESERFHDNMDAFV-----KIIKTEVMNKGSV-IAYIKAENVMGYEFSGKK 187 Query: 269 HE--AGDVMGGHAIRILGWGIENGV-------PYWLVANSWNVDWGDNGFFKI-LRGENH 318 + GD HA+ I+G+G N V YW+V NSW WGD G+FK+ + G H Sbjct: 188 VQNLCGDDTADHAVNIVGYG--NYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTH 245 Query: 319 C 319 C Sbjct: 246 C 246 >3OIS-A nrPDB Length = 291 Score = 30.8 bits (68), Expect = 0.80, Method: Compositional matrix adjust. Identities = 49/220 (22%), Positives = 91/220 (41%), Gaps = 27/220 (12%) Query: 98 QIRDQGSCGSCWAFGAVEAMS-DRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPS 156 Q+ DQG GSC A A+ +RI + + + E L + +G + Y S Sbjct: 68 QVYDQGRIGSCTANALAAAIQFERI----HDKQSPEFIPSRLFIYYNERKIEG-HVNYDS 122 Query: 157 GAWNFWTRKGLVSGGVYNSH-IGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGY 215 GA ++ G+ H +G P P G P + P + Sbjct: 123 GA--------MIRDGIKVLHKLGVCPEKEWPY-----GDTPADPRTEEFPPGAPASKKPS 169 Query: 216 STSYKEDKHYGYTSYS-VSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYK----HE 270 YK+ ++Y T YS V+ + A + P F+V++ ++ S + + Sbjct: 170 DQCYKDAQNYKITEYSRVAQDIDHLKACLAVGSPFVFGFSVYNSWVGNNSLPVRIPLPTK 229 Query: 271 AGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFF 310 + GGHA+ +G+ ++ + ++ + NSW + G++G+F Sbjct: 230 NDTLEGGHAVLCVGY--DDEIRHFRIRNSWGNNVGEDGYF 267 >4K7C-A nrPDB Length = 446 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVP-YWLVANSWNVDWGDNGFF 310 +DF K+ + + G+ + HA+ + G + +G P W V NSW G+ G+F Sbjct: 345 TDFTMTKAE--RLDYGESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 >4KPO-A nrPDB Length = 330 Score = 27.7 bits (60), Expect = 7.1, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 4/65 (6%) Query: 243 IYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHA---IRILGWGIENG-VPYWLVAN 298 I+ + PV A V + T+K GV + E + GH + + W EN Y ++ Sbjct: 251 IFLHDPVSFAALVRPELFTFKKGVVRVETQGICVGHTSMDMLLKKWNSENPWTGYSPISV 310 Query: 299 SWNVD 303 +W VD Sbjct: 311 AWTVD 315 >1E5M-A nrPDB Length = 416 Score = 27.7 bits (60), Expect = 7.7, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 13/53 (24%) Query: 26 LSDDMINYINKQNTTWQA-------------GRNFYNVDISYLKKLCGTVLGG 65 L +M++YIN T+ A G + YN+ +S K + G +LGG Sbjct: 296 LKPEMVSYINAHGTSTPANDVTETRAIKQALGNHAYNIAVSSTKSMTGHLLGG 348 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1MIR-A nrPDB 448 e-126 3PBH-A nrPDB 426 e-120 1CPJ-A nrPDB 361 e-100 3CBK-A nrPDB 359 e-100 4I04-A nrPDB 331 4e-91 2DCB-A nrPDB 322 1e-88 4I05-A nrPDB 309 1e-84 5OGQ-A nrPDB 301 3e-82 4HWY-A nrPDB 290 7e-79 7PCK-A nrPDB 285 3e-77 3QT4-A nrPDB 280 7e-76 1CJL-A nrPDB 277 7e-75 5FPW-A nrPDB 269 1e-72 1CSB-B nrPDB 268 3e-72 2C0Y-A nrPDB 262 2e-70 3QJ3-A nrPDB 257 4e-69 2O6X-A nrPDB 255 2e-68 1JQP-A nrPDB 250 8e-67 4QRX-A nrPDB 248 2e-66 3HWN-A nrPDB 248 2e-66 1PCI-A nrPDB 247 8e-66 3PDF-A nrPDB 243 9e-65 6CZS-A nrPDB 240 6e-64 1SP4-B nrPDB 240 7e-64 3OF9-A nrPDB 240 9e-64 1S4V-A nrPDB 239 1e-63 5EF4-A nrPDB 238 2e-63 3P5W-A nrPDB 235 2e-62 1NB3-A nrPDB 234 4e-62 4YYR-A nrPDB 233 1e-61 3KFQ-A nrPDB 230 6e-61 4P6E-A nrPDB 229 2e-60 2FO5-A nrPDB 228 2e-60 4BS5-A nrPDB 228 2e-60 1AEC-A nrPDB 225 1e-59 2VHS-A nrPDB 224 5e-59 5JA7-A nrPDB 222 1e-58 1CQD-A nrPDB 222 1e-58 3BCN-A nrPDB 222 2e-58 4YYW-A nrPDB 221 3e-58 2PNS-A nrPDB 221 4e-58 2ACT-A nrPDB 220 9e-58 6BKI-A nrPDB 217 4e-57 1IWD-A nrPDB 216 1e-56 1O0E-A nrPDB 215 2e-56 1YAL-A nrPDB 215 3e-56 3F75-A nrPDB 212 3e-55 1PPO-A nrPDB 210 9e-55 6MIS-A nrPDB 207 5e-54 2BDZ-A nrPDB 207 6e-54 2CIO-A nrPDB 205 3e-53 6EXO-A nrPDB 204 5e-53 5A24-A nrPDB 199 1e-51 4YYQ-A nrPDB 197 4e-51 4PI3-A nrPDB 197 5e-51 2B1M-A nrPDB 197 5e-51 1GEC-E nrPDB 194 4e-50 5VPK-A nrPDB 194 6e-50 3BPF-A nrPDB 191 3e-49 1DEU-A nrPDB 190 5e-49 3IOQ-A nrPDB 190 1e-48 3BPM-A nrPDB 188 2e-48 1ICF-A nrPDB 188 4e-48 1XKG-A nrPDB 186 1e-47 5VCN-A nrPDB 184 5e-47 3U8E-A nrPDB 175 2e-44 1M6D-A nrPDB 174 4e-44 1EF7-A nrPDB 173 9e-44 5JT8-A nrPDB 170 1e-42 3CH2-X nrPDB 166 9e-42 4OEL-A nrPDB 156 2e-38 4CDF-B nrPDB 138 3e-33 5I4H-B nrPDB 126 1e-29 5I4H-A nrPDB 125 2e-29 4OEM-B nrPDB 98 5e-21 Sequences not found previously or not previously below threshold: 4CI7-A nrPDB 68 6e-12 4D59-A nrPDB 68 8e-12 3OIS-A nrPDB 60 2e-09 4K7C-A nrPDB 45 4e-05 5WDK-A nrPDB 38 0.006 2CB5-A nrPDB 36 0.019 2EKL-A nrPDB 32 0.51 3OME-A nrPDB 29 2.1 2Z51-A nrPDB 29 2.3 5O4O-C nrPDB 29 4.1 3LY6-A nrPDB 29 4.1 3P11-A nrPDB 29 4.2 5Y34-A nrPDB 27 8.0 >1MIR-A nrPDB Length = 322 Score = 448 bits (1153), Expect = e-126, Method: Composition-based stats. Identities = 317/322 (98%), Positives = 318/322 (98%) Query: 18 HDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPNLPERVGFSED 77 HDKPS HPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGP LPERVGFSED Sbjct: 1 HDKPSFHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPKLPERVGFSED 60 Query: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 INLPESFDAREQWSNCPTIAQIRDQGSCGS WAFGAVEAMSDRICIHTNGRVNVEVSAED Sbjct: 61 INLPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAED 120 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG+RPP Sbjct: 121 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPP 180 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS Sbjct: 181 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 240 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWN DWGDNGFFKILRGEN Sbjct: 241 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGEN 300 Query: 318 HCGIESEIVAGIPRTQQYWGRF 339 HCGIESEIVAGIPRTQQYWGRF Sbjct: 301 HCGIESEIVAGIPRTQQYWGRF 322 >3PBH-A nrPDB Length = 317 Score = 426 bits (1096), Expect = e-120, Method: Composition-based stats. Identities = 254/314 (80%), Positives = 287/314 (91%) Query: 20 KPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPNLPERVGFSEDIN 79 +PS HPLSD+++NY+NK+NTTWQAG NFYNVD+SYLK+LCGT LGGP P+RV F+ED+ Sbjct: 4 RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK 63 Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP SFDAREQW CPTI +IRDQGSCGSCWAFGAVEA+SDRICIHTN V+VEVSAEDLL Sbjct: 64 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 123 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 TCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCEHHVNGSRPPCT Sbjct: 124 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 183 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 GEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF+V+SDF Sbjct: 184 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 243 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 L YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKILRG++HC Sbjct: 244 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 303 Query: 320 GIESEIVAGIPRTQ 333 GIESE+VAGIPRT Sbjct: 304 GIESEVVAGIPRTD 317 >1CPJ-A nrPDB Length = 260 Score = 361 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 258/260 (99%), Positives = 259/260 (99%) Query: 74 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 133 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV Sbjct: 1 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 60 Query: 134 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG Sbjct: 61 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 120 Query: 194 SRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 180 Query: 254 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKIL 313 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWN DWGDNGFFKIL Sbjct: 181 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 240 Query: 314 RGENHCGIESEIVAGIPRTQ 333 RGENHCGIESEIVAGIPRTQ Sbjct: 241 RGENHCGIESEIVAGIPRTQ 260 >3CBK-A nrPDB Length = 266 Score = 359 bits (922), Expect = e-100, Method: Composition-based stats. Identities = 215/266 (80%), Positives = 241/266 (90%) Query: 74 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 133 F+ED+ LP SFDAREQW CPTI +IRDQGSCGS WAFGAVEA+SDRICIHTN V+VEV Sbjct: 1 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEV 60 Query: 134 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 SAEDLLTCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCE HVNG Sbjct: 61 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNG 120 Query: 194 SRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 180 Query: 254 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKIL 313 +V+SDFL YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKIL Sbjct: 181 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 240 Query: 314 RGENHCGIESEIVAGIPRTQQYWGRF 339 RG++HCGIESE+VAGIPRT QYW + Sbjct: 241 RGQDHCGIESEVVAGIPRTDQYWEKI 266 >4I04-A nrPDB Length = 323 Score = 331 bits (847), Expect = 4e-91, Method: Composition-based stats. Identities = 160/316 (50%), Positives = 211/316 (66%), Gaps = 12/316 (3%) Query: 22 SSHPLSDDMINYINKQ-NTTWQAGR--NFYNVDISYLKKLCGTVLGGPNLPERVGFSED- 77 PLSDD+I+YIN+ N W+A + F+++D + ++ G P+L + D Sbjct: 8 KFEPLSDDIISYINEHPNAGWRAEKSNRFHSLDDARIQ--MGARREEPDLRRTRRPTVDH 65 Query: 78 ----INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 133 + +P SFD+R++W C +IA IRDQ CGS WAFGAVEAMSDR CI + G+ NVE+ Sbjct: 66 NDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVEL 125 Query: 134 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 193 SA DLL+CC CG GC GG AW++W ++G+V+G +H GC PY P CEHH G Sbjct: 126 SAVDLLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKG 184 Query: 194 SRPPC-TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGA 252 PPC + TP+C + C+ Y T Y +DKH G +SY+V + EK I EI K GPVE Sbjct: 185 KYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAG 244 Query: 253 FTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKI 312 FTV+ DFL YKSG+YKH G+ +GGHAIRI+GWG+EN PYWL+ANSWN DWG+NG+F+I Sbjct: 245 FTVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRI 304 Query: 313 LRGENHCGIESEIVAG 328 +RG + C IESE+ AG Sbjct: 305 VRGRDECSIESEVTAG 320 >2DCB-A nrPDB Length = 256 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 215/256 (83%), Positives = 241/256 (94%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPESFDAREQW NCPTI +IRDQGSCGSCWAFGAVEA+SDRICIH+NGRVNVEVSAED+L Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 TCCG +CGDGCNGG+PSGAWNFWT+KGLVSGG+YNSH+GC PY+IPPCEHHVNGSRPPCT Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 GEGDTPKC+K CE GYS SYKEDKH+G +SYSV+++EKEIMAEIYKNGPVEGAF+V+SDF Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDF 180 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 L YKSGVY+H +G++MGGHAIRILGWG+ENG PYWLV NSWN DWGDNGFFKILRG++HC Sbjct: 181 LLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHC 240 Query: 320 GIESEIVAGIPRTQQY 335 GIESEIVAG+P T QY Sbjct: 241 GIESEIVAGMPCTHQY 256 >4I05-A nrPDB Length = 285 Score = 309 bits (791), Expect = 1e-84, Method: Composition-based stats. Identities = 147/276 (53%), Positives = 187/276 (67%), Gaps = 7/276 (2%) Query: 59 CGTVLGGPNLPERVGFSED-----INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGA 113 G P+L + D + +P SFD+R++W C +IA IRDQ CGSCWAFGA Sbjct: 8 MGARREEPDLRRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGA 67 Query: 114 VEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVY 173 VEAMSDR CI + G+ NVE+SA DLL+CC CG GC GG AW++W ++G+V+G Sbjct: 68 VEAMSDRSCIQSGGKQNVELSAVDLLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSK 126 Query: 174 NSHIGCLPYTIPPCEHHVNGSRPPC-TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSV 232 +H GC PY P CEHH G PPC + TP+C + C+ Y T Y +DKH G +SY+V Sbjct: 127 ENHAGCEPYPFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNV 186 Query: 233 SDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVP 292 + EK I EI K GPVE FTV+ DFL YKSG+YKH G+ +GGHAIRI+GWG+EN P Sbjct: 187 KNDEKAIQKEIMKYGPVEAGFTVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAP 246 Query: 293 YWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAG 328 YWL+ANSWN DWG+NG+F+I+RG + C IESE+ AG Sbjct: 247 YWLIANSWNEDWGENGYFRIVRGRDECSIESEVTAG 282 >5OGQ-A nrPDB Length = 254 Score = 301 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 143/252 (56%), Positives = 181/252 (71%), Gaps = 2/252 (0%) Query: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 + +P SFD+R++W C +IA IRDQ CGSCWAFGAVEAMSDR CI + G+ NVE+SA D Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 LL+CC CG GC GG AW++W ++G+V+G +H GC PY P CEHH G PP Sbjct: 61 LLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPP 119 Query: 198 C-TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 C + TP+C + C+ Y T Y +DKH G +SY+V + EK I EI K GPVE FTV+ Sbjct: 120 CGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVY 179 Query: 257 SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE 316 DFL YKSG+YKH G+ +GGHAIRI+GWG+EN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 180 EDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGR 239 Query: 317 NHCGIESEIVAG 328 + C IESE+ AG Sbjct: 240 DECSIESEVTAG 251 >4HWY-A nrPDB Length = 340 Score = 290 bits (741), Expect = 7e-79, Method: Composition-based stats. Identities = 140/316 (44%), Positives = 181/316 (57%), Gaps = 24/316 (7%) Query: 26 LSDDMINYINKQNTT-WQAGRN--FYNVDISYLKKLCGTVLGGPN---LPERVGFSEDIN 79 LS ++ +N+ N W+A + N+ + K+L G + N LP+R E+ Sbjct: 32 LSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEAR 91 Query: 80 --LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 LP SFD+ E W NCPTI QI DQ +CGSCWA A AMSDR C G +V +SA D Sbjct: 92 APLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCT-MGGVQDVHISAGD 150 Query: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGS--R 195 LL CC CGDGCNGG P AW +++ GLVS C PY P C HH Sbjct: 151 LLACCS-DCGDGCNGGDPDRAWAYFSSTGLVSD-------YCQPYPFPHCSHHSKSKNGY 202 Query: 196 PPCTGEG-DTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFT 254 PPC+ DTPKCN C+ + + +TSY++ E + M E++ GP E AF Sbjct: 203 PPCSQFNFDTPKCNYTCD---DPTIPVVNYRSWTSYAL-QGEDDYMRELFFRGPFEVAFD 258 Query: 255 VFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 V+ DF+ Y SGVY H +G +GGHA+R++GWG NGVPYW +ANSWN +WG +G+F I R Sbjct: 259 VYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRR 318 Query: 315 GENHCGIESEIVAGIP 330 G + CGIE AGIP Sbjct: 319 GSSECGIEDGGSAGIP 334 >7PCK-A nrPDB Length = 314 Score = 285 bits (728), Expect = 3e-77, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 142/345 (41%), Gaps = 58/345 (16%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG-- 60 W L + + D+ S + + + YI+ N G + Y + +++L + Sbjct: 11 WELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEE 70 Query: 61 --TVLGGPNLPERVGFSEDI--------NLPESFDAREQWSNCPTIAQIRDQGSCGSCWA 110 + G +P S D P+S D R++ + +++QG CGSCWA Sbjct: 71 VVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGY----VTPVKNQGQCGSCWA 126 Query: 111 FGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRK-GLVS 169 F +V A+ ++ T +N +S ++L+ C + DGC GGY + A+ + + G+ S Sbjct: 127 FSSVGALEGQLKKKTGKLLN--LSPQNLVDC--VSENDGCGGGYMTNAFQYVQKNRGIDS 182 Query: 170 GGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTS 229 Y C ++ G C G + P+ N Sbjct: 183 EDAYPYVG-----QEESCMYNPTGKAAKCRGYREIPEGN--------------------- 216 Query: 230 YSVSDSEKEIMAEIYKNGPVEGAFTVF-SDFLTYKSGVYK-HEAGDVMGGHAIRILGWGI 287 EK + + + GPV A + F Y GVY HA+ +G+GI Sbjct: 217 ------EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI 270 Query: 288 ENGVPYWLVANSWNVDWGDNGFFKILRGENH-CGIESEIVAGIPR 331 + G +W++ NSW +WG+ G+ + R +N+ CGI + +A P+ Sbjct: 271 QKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN--LASFPK 313 >3QT4-A nrPDB Length = 329 Score = 280 bits (715), Expect = 7e-76, Method: Composition-based stats. Identities = 70/343 (20%), Positives = 133/343 (38%), Gaps = 59/343 (17%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNV------DISYLK 56 WS L+ + +S ++ + D + I + N ++ G Y+ D+S + Sbjct: 27 WSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQFGDMSKEE 86 Query: 57 KLCGTVLGGPNLPERVGFSEDINLP---------ESFDAREQWSNCPTIAQIRDQGSCGS 107 L G P+ E++ +P S D R +++++DQG CGS Sbjct: 87 FLAYVNRGKAQKPKH---PENLRMPYVSSKKPLAASVDWR-----SNAVSEVKDQGQCGS 138 Query: 108 CWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGL 167 W+F A+ ++ + +S ++L+ C GC+GG+ A+++ G+ Sbjct: 139 SWSFSTTGAVEGQLALQRGRL--TSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDYGI 196 Query: 168 VSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGY 227 +S Y C + S +G D P Sbjct: 197 MSESAYPYEA-----QGDYCRFDSSQSVTTLSGYYDLP---------------------- 229 Query: 228 TSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMG-GHAIRILGWG 286 S E + + + GPV A + Y G++ + + H + ++G+G Sbjct: 230 -----SGDENSLADAVGQAGPVAVAIDATDELQFYSGGLFYDQTCNQSDLNHGVLVVGYG 284 Query: 287 IENGVPYWLVANSWNVDWGDNGFFKILRGE-NHCGIESEIVAG 328 +NG YW++ NSW WG++G+++ +R N+CGI + Sbjct: 285 SDNGQDYWILKNSWGSGWGESGYWRQVRNYGNNCGIATAASYP 327 >1CJL-A nrPDB Length = 312 Score = 277 bits (707), Expect = 7e-75, Method: Composition-based stats. Identities = 79/343 (23%), Positives = 133/343 (38%), Gaps = 55/343 (16%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTV 62 W+ +++ + + + I N ++ G++ + + ++ + Sbjct: 8 WTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEE 66 Query: 63 L-----GGPNLPERVG--FSEDI--NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGA 113 G N R G F E + P S D RE+ + +++QG CGS WAF A Sbjct: 67 FRQVMNGLQNRKPRKGKVFQEPLFYEAPRSVDWREKGY----VTPVKNQGQCGSSWAFSA 122 Query: 114 VEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVY 173 A+ ++ T + +S ++L+ C G + +GCNGG A+ + G G+ Sbjct: 123 TGALEGQMFRKTGRL--ISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNG----GLD 176 Query: 174 NSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVS 233 + T C+++ S G D PK Sbjct: 177 SEESYPYEATEESCKYNPKYSVANDAGFVDIPK--------------------------- 209 Query: 234 DSEKEIMAEIYKNGPVEGAFTV-FSDFLTYKSGVY-KHEAGDVMGGHAIRILGWGIE--- 288 EK +M + GP+ A FL YK G+Y + + H + ++G+G E Sbjct: 210 -QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTE 268 Query: 289 -NGVPYWLVANSWNVDWGDNGFFKILRG-ENHCGIESEIVAGI 329 +G YWLV NSW +WG G+ K+ + NHCGI S Sbjct: 269 SDGNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 311 >5FPW-A nrPDB Length = 321 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 122/317 (38%), Positives = 168/317 (52%), Gaps = 20/317 (6%) Query: 26 LSDDMINYINKQNT-TWQAGRN--FYNVDISYLKKLCGTVLGGPNLPERVGFSED---IN 79 L+ ++ IN+ N W+A N N+ + K+L G + + V F+E+ Sbjct: 15 LTKTFVDRINQLNGGMWKAVYNGKMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTE 74 Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPESFD+ E+W NCPTI +I DQ +C + WA +SDR C G + +SA LL Sbjct: 75 LPESFDSAEKWPNCPTIREIADQSACRASWAVSTASVISDRYCTV-GGVQQLRISAAHLL 133 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHH-VNGSRPPC 198 +CC G GG+P AW ++ G+ S C PY P CEH G++ PC Sbjct: 134 SCCKQCGGGC-KGGFPGFAWRYYVEYGIASS-------YCQPYPFPHCEHRGAQGNKTPC 185 Query: 199 TGEG-DTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257 + DTPKC C S K+ G +Y + E++ E+Y NGP F V++ Sbjct: 186 SKYNFDTPKCQATCT---DKSIPLVKYRGSATYLLLHGEEDYKRELYFNGPFVAVFYVYT 242 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 D YKSGVY+H GD +GG A++++GWG NG PYW VAN+W+ DWG +G+ ILRG N Sbjct: 243 DLFAYKSGVYRHVDGDFLGGTAVKVVGWGKLNGTPYWKVANTWDTDWGMDGYLLILRGNN 302 Query: 318 HCGIESEIVAGIPRTQQ 334 C IE AG P T Q Sbjct: 303 ECNIEHLGFAGTPETSQ 319 >1CSB-B nrPDB Length = 205 Score = 268 bits (685), Expect = 3e-72, Method: Composition-based stats. Identities = 171/205 (83%), Positives = 191/205 (93%) Query: 129 VNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCE 188 V+VEVSAEDLLTCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCE Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 189 HHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGP 248 HHVNGSRPPCTGEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGP Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 120 Query: 249 VEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNG 308 VEGAF+V+SDFL YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNG Sbjct: 121 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 180 Query: 309 FFKILRGENHCGIESEIVAGIPRTQ 333 FFKILRG++HCGIESE+VAGIPRT Sbjct: 181 FFKILRGQDHCGIESEVVAGIPRTD 205 >2C0Y-A nrPDB Length = 315 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 76/342 (22%), Positives = 138/342 (40%), Gaps = 56/342 (16%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG-- 60 W L + +++ + + + ++ N G + Y++ +++L + Sbjct: 12 WHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEE 71 Query: 61 ------TVLGGPNLPERVGFSEDIN--LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFG 112 ++ + + + N LP+S D RE+ + +++ QGSCG+ WAF Sbjct: 72 VMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKG----CVTEVKYQGSCGAAWAFS 127 Query: 113 AVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGD-GCNGGYPSGAWNFWTRK-GLVSG 170 AV A+ ++ + T V +SA++L+ C + G+ GCNGG+ + A+ + G+ S Sbjct: 128 AVGALEAQLKLKTGKL--VSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSD 185 Query: 171 GVYNSHIGCLPYTI--PPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYT 228 Y PY C++ C+ + P Sbjct: 186 ASY-------PYKAMDQKCQYDSKYRAATCSKYTELPYGR-------------------- 218 Query: 229 SYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGI 287 E + + GPV F Y+SGVY + H + ++G+G Sbjct: 219 -------EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGD 271 Query: 288 ENGVPYWLVANSWNVDWGDNGFFKILRGE-NHCGIESEIVAG 328 NG YWLV NSW ++G+ G+ ++ R + NHCGI S Sbjct: 272 LNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYP 313 >3QJ3-A nrPDB Length = 331 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 83/347 (23%), Positives = 136/347 (39%), Gaps = 58/347 (16%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTV 62 W + + +A ++ + + + N ++ G Y + ++ + Sbjct: 22 WENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNLFTDMTPEE 81 Query: 63 LG-----------------GPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSC 105 + E +G + + P SFD R+Q ++ +++QGSC Sbjct: 82 MKAYTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGM----VSPVKNQGSC 137 Query: 106 GSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRK 165 GS WAF + A+ ++ I + VS + L+ C + GC+GG+ + A+ + + Sbjct: 138 GSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDC--VPNALGCSGGWMNDAFTYVAQN 195 Query: 166 GLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHY 225 G + G PY + H Y + + Sbjct: 196 GGIDS------EGAYPYEMADGNCH------------------------YDPNQVAARLS 225 Query: 226 GYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMG-GHAIRILG 284 GY S E + + GPV AF F +Y GVY + + HA+ I+G Sbjct: 226 GYVYLSGP-DENMLADMVATKGPVAVAFDADDPFGSYSGGVYYNPTCETNKFTHAVLIVG 284 Query: 285 WGIENGVPYWLVANSWNVDWGDNGFFKILRG-ENHCGIESEIVAGIP 330 +G ENG YWLV NSW WG +G+FKI R NHCGI VA +P Sbjct: 285 YGNENGQDYWLVKNSWGDGWGLDGYFKIARNANNHCGIA--GVASVP 329 >2O6X-A nrPDB Length = 310 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 80/346 (23%), Positives = 136/346 (39%), Gaps = 54/346 (15%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTV 62 W A D+ + + + + +I + N G Y + ++ + Sbjct: 5 WHQWKRMYNKEYNGADDQHRRN-IWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEE 63 Query: 63 LGGPNLPERVGFSEDIN-----------LPESFDAREQWSNCPTIAQIRDQGSCGSCWAF 111 L E S+ ++ +P+ D RE + +++DQG+CGS WAF Sbjct: 64 FKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGY----VTEVKDQGNCGSGWAF 119 Query: 112 GAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGG 171 M + N R ++ S + L+ C +GC GG A+ + + GL + Sbjct: 120 STTGTMEGQYM--KNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQFGLETES 177 Query: 172 VYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYS 231 Y PYT + NK T + Sbjct: 178 SY-------PYTAVEGQCRY----------------NKQLGVAKVTGFYTVH-------- 206 Query: 232 VSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHE-AGDVMGGHAIRILGWGIENG 290 S SE E+ + GP A V SDF+ Y+SG+Y+ + + HA+ +G+G + G Sbjct: 207 -SGSEVELKNLVGAEGPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG 265 Query: 291 VPYWLVANSWNVDWGDNGFFKILRGE-NHCGIESEIVAGIPRTQQY 335 YW+V NSW + WG+ G+ +++R N CGI S +A +P ++ Sbjct: 266 TDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIAS--LASLPMVARF 309 >1JQP-A nrPDB Length = 438 Score = 250 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 90/317 (28%), Positives = 142/317 (44%), Gaps = 46/317 (14%) Query: 29 DMINYINKQNTTWQAG--RNFYNVDISYLKKLCG---TVLGGPNLPERVGFSEDI-NLPE 82 + + IN +W A R + + I L + G +L P + I +LPE Sbjct: 149 NFVKAINSVQKSWTATTYRRYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPE 208 Query: 83 SFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCC 142 S+D R ++ +R+Q SCGSC++F ++ + RI I TN +S +++++C Sbjct: 209 SWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCS 267 Query: 143 GIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGE 201 GC+GG+P A + G+V C PYT Sbjct: 268 P--YAQGCDGGFPYLIAGKYAQDFGVVEE-------NCFPYTATDAPCK----------- 307 Query: 202 GDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLT 261 PK N Y ++Y + +E + E+ K+GP+ AF V DFL Sbjct: 308 ---PKEN-------CLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLH 357 Query: 262 YKSGVYKHE------AGDVMGGHAIRILGWGIE--NGVPYWLVANSWNVDWGDNGFFKIL 313 Y SG+Y H + HA+ ++G+G + G+ YW+V NSW WG++G+F+I Sbjct: 358 YHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIR 417 Query: 314 RGENHCGIESEIVAGIP 330 RG + C IES +A IP Sbjct: 418 RGTDECAIESIAMAAIP 434 >4QRX-A nrPDB Length = 363 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 85/338 (25%), Positives = 132/338 (39%), Gaps = 61/338 (18%) Query: 8 LSCLLALTSAHDKPSSHPLSDDMINYI---NKQNTTWQAGRNFYNVDIS---YLKKLCGT 61 L + +K + D + YI NK+N ++ G N + D+S + +K G+ Sbjct: 71 LKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVF-ADMSNDEFKEKYTGS 129 Query: 62 VLGGPNLPE----RVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAM 117 + G E V D+N+PE D R++ + + +++QGSCGS WAF AV + Sbjct: 130 IAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGA----VTPVKNQGSCGSAWAFSAVSTI 185 Query: 118 SDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHI 177 I I T E S ++LL C + GCNGGYP A + G+ Y Sbjct: 186 ESIIKIRTGNLN--EYSEQELLDCD--RRSYGCNGGYPWSALQLVAQYGIHYRNTY---- 237 Query: 178 GCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEK 237 PY G + C P K Y + Sbjct: 238 ---PY---------EGVQRYCRSREKGPYAAKTDGVRQVQPY----------------NE 269 Query: 238 EIMAEIYKNGPVEGAFTVF-SDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLV 296 + N PV DF Y+ G++ G+ + HA+ +G+G Y L+ Sbjct: 270 GALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKV-DHAVAAVGYG----PNYILI 324 Query: 297 ANSWNVDWGDNGFFKILRGENH----CGIESEIVAGIP 330 NSW WG+NG+ +I RG + CG+ + + Sbjct: 325 RNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVK 362 >3HWN-A nrPDB Length = 258 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 76/295 (25%), Positives = 116/295 (39%), Gaps = 54/295 (18%) Query: 51 DISYLKKLCGTVL-----GGPNLPERVG--FSEDI--NLPESFDAREQWSNCPTIAQIRD 101 ++ + G N R G F E + P S D RE+ + +++ Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGY----VTPVKN 56 Query: 102 QGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNF 161 QG CGSCWAF A A+ ++ T + +S ++L+ C G Q +GCNGG A+ + Sbjct: 57 QGQCGSCWAFSATGALEGQMFRKTGRL--ISLSEQNLVDCSGPQGNEGCNGGLMDYAFQY 114 Query: 162 WTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKE 221 G G+ + T C+++ S G D PK Sbjct: 115 VQDNG----GLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK--------------- 155 Query: 222 DKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDFLTYKSGVY-KHEAGDVMGGHA 279 EK +M + GP+ A FL YK G+Y + + H Sbjct: 156 -------------QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHG 202 Query: 280 IRILGWGIE----NGVPYWLVANSWNVDWGDNGFFKILRG-ENHCGIESEIVAGI 329 + ++G+G E + YWLV NSW +WG G+ K+ + NHCGI S Sbjct: 203 VLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 257 >1PCI-A nrPDB Length = 322 Score = 247 bits (629), Expect = 8e-66, Method: Composition-based stats. Identities = 79/336 (23%), Positives = 132/336 (39%), Gaps = 52/336 (15%) Query: 8 LSCLLALTSAHDKPSSHPLSDDMINYI---NKQNTTWQAGRNFYN--VDISYLKKLCGTV 62 L+ + +K + D +NYI NK+N ++ G N + + + +K G++ Sbjct: 27 LNHNKFYENVDEKLYRFEIFKDNLNYIDETNKKNNSYWLGLNEFADLSNDEFNEKYVGSL 86 Query: 63 LG---GPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSD 119 + + E + +NLPE+ D R++ + + +R QGSCGSCWAF AV + Sbjct: 87 IDATIEQSYDEEFINEDIVNLPENVDWRKKGA----VTPVRHQGSCGSCWAFSAVATVEG 142 Query: 120 RICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGC 179 I T VE+S ++L+ C + GC GGYP A + + G+ Y Sbjct: 143 INKIRTGKL--VELSEQELVDC--ERRSHGCKGGYPPYALEYVAKNGIHLRSKY------ 192 Query: 180 LPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEI 239 PY P + ++E + Sbjct: 193 -PYKAKQGTCRAKQVGGPIVKTSGVGRVQ------------------------PNNEGNL 227 Query: 240 MAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANS 299 + I K + F YK G+++ G + G A+ +G+G G Y L+ NS Sbjct: 228 LNAIAKQPVSVVVESKGRPFQLYKGGIFEGPCGTKVDG-AVTAVGYGKSGGKGYILIKNS 286 Query: 300 WNVDWGDNGFFKILRGENHCGIESEIVAGIPRTQQY 335 W WG+ G+ +I R S V G+ ++ Y Sbjct: 287 WGTAWGEKGYIRIKRAPG----NSPGVCGLYKSSYY 318 >3PDF-A nrPDB Length = 441 Score = 243 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 93/318 (29%), Positives = 145/318 (45%), Gaps = 47/318 (14%) Query: 29 DMINYINKQNTTWQAG--RNFYNVDISYLKKLCGTVLGGPNLPERVGFSEDIN-----LP 81 + + IN +W A + + + + + G P+ + +I LP Sbjct: 149 NFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILFLP 208 Query: 82 ESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTC 141 S+D R ++ +R+Q SCGSC++F ++ + RI I TN +S +++++C Sbjct: 209 TSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 267 Query: 142 CGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 Q GC GG+P A + GLV C PYT G+ PC Sbjct: 268 S--QYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT---------GTDSPCKM 309 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFL 260 + D C YS+ Y HY Y + E + E+ +GP+ AF V+ DFL Sbjct: 310 KED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAFEVYDDFL 357 Query: 261 TYKSGVYKHE------AGDVMGGHAIRILGWGIEN--GVPYWLVANSWNVDWGDNGFFKI 312 YK G+Y H + HA+ ++G+G ++ G+ YW+V NSW WG+NG+F+I Sbjct: 358 HYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRI 417 Query: 313 LRGENHCGIESEIVAGIP 330 RG + C IES VA P Sbjct: 418 RRGTDECAIESIAVAATP 435 >6CZS-A nrPDB Length = 335 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 75/333 (22%), Positives = 126/333 (37%), Gaps = 49/333 (14%) Query: 10 CLLALTSAHDKPSSHPLSDDMINYINKQNT---TWQAGRNFYNVDISYLK---KLCGTVL 63 ++ IN N T++ N ++ D+S+ + K + Sbjct: 42 HRKTYSTEEYHHRLQ-TFASNWRKINAHNNGNHTFKMALNQFS-DMSFAEIKHKYLWSEP 99 Query: 64 GGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICI 123 + + P S D R++ + ++ +++QG+CGS W F A+ I I Sbjct: 100 QNCSATKSNYLRGTGPYPPSVDWRKKGN---FVSPVKNQGACGSSWTFSTTGALESAIAI 156 Query: 124 HTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFW-TRKGLVSGGVYNSHIGCLPY 182 T + ++ + L+ C GC GG PS A+ + KG++ Y PY Sbjct: 157 ATGKM--LSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTY-------PY 207 Query: 183 TIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAE 242 K + E+ ++ Sbjct: 208 QGKDGYCKFQ-------------------------PGKAIGFVKDVANITIYDEEAMVEA 242 Query: 243 IYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMG---GHAIRILGWGIENGVPYWLVANS 299 + PV AF V DF+ Y++G+Y + HA+ +G+G +NG+PYW+V NS Sbjct: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302 Query: 300 WNVDWGDNGFFKILRGENHCGIESEIVAGIPRT 332 W WG NG+F I RG+N CG+ + IP Sbjct: 303 WGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335 >1SP4-B nrPDB Length = 205 Score = 240 bits (612), Expect = 7e-64, Method: Composition-based stats. Identities = 171/205 (83%), Positives = 193/205 (94%) Query: 128 RVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPC 187 RVNVEVSAED+LTCCG +CGDGCNGG+PSGAWNFWT+KGLVSGG+YNSH+GC PY+IPPC Sbjct: 1 RVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPC 60 Query: 188 EHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNG 247 EHHVNGSRPPCTGEGDTPKCNK CE GYS SYKEDKH+G +SYSV+++EKEIMAEIYKNG Sbjct: 61 EHHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNG 120 Query: 248 PVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDN 307 PVEGAF+V+SDFL YKSGVY+H +G++MGGHAIRILGWG+ENG PYWLV NSWN DWGDN Sbjct: 121 PVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDN 180 Query: 308 GFFKILRGENHCGIESEIVAGIPRT 332 GFFKILRG++HCGIESEIVAG+P T Sbjct: 181 GFFKILRGQDHCGIESEIVAGMPCT 205 >3OF9-A nrPDB Length = 221 Score = 240 bits (611), Expect = 9e-64, Method: Composition-based stats. Identities = 71/258 (27%), Positives = 107/258 (41%), Gaps = 45/258 (17%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 P S D RE+ + +++QG CGSCWAF A A+ ++ T + +S ++L Sbjct: 1 EAPRSVDWREKGY----VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRL--ISLSEQNL 54 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C G Q +GCNGG A+ + G G+ + T C+++ S Sbjct: 55 VDCSGPQGNEGCNGGLMDYAFQYVQDNG----GLDSEESYPYEATEESCKYNPKYSVAND 110 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FS 257 TG D PK EK +M + GP+ A Sbjct: 111 TGFVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHE 142 Query: 258 DFLTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNVDWGDNGFFKI 312 FL YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 143 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 202 Query: 313 LRG-ENHCGIESEIVAGI 329 + NHCGI S Sbjct: 203 AKDRRNHCGIASAASYPT 220 >1S4V-A nrPDB Length = 229 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 71/260 (27%), Positives = 110/260 (42%), Gaps = 45/260 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P S D R++ + + ++DQG CGSCWAF + A+ I TN V +S ++L+ Sbjct: 2 VPASVDWRKKGA----VTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKL--VSLSEQELV 55 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GCNGG A+ F ++G ++ PY V+ P Sbjct: 56 DCDTDQ-NQGCNGGLMDYAFEFIKQRGGIT------TEANYPYEAYDGTCDVSKENAPA- 107 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSD 258 D H +V ++++ + + N PV A SD Sbjct: 108 -------------------VSIDGHE-----NVPENDENALLKAVANQPVSVAIDAGGSD 143 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIE-NGVPYWLVANSWNVDWGDNGFFKILRG-- 315 F Y GV+ G + H + I+G+G +G YW V NSW +WG+ G+ ++ RG Sbjct: 144 FQFYSEGVFTGSCGTEL-DHGVAIVGYGTTIDGTKYWTVKNSWGPEWGEKGYIRMERGIS 202 Query: 316 --ENHCGIESEIVAGIPRTQ 333 E CGI E I ++ Sbjct: 203 DKEGLCGIAMEASYPIKKSS 222 >5EF4-A nrPDB Length = 385 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 71/332 (21%), Positives = 118/332 (35%), Gaps = 64/332 (19%) Query: 21 PSSHPLSDDMINYINKQNTT---WQAGRNFY-------------NVDISYLKKLCGTVLG 64 P + + I++ N ++ N + N IS+ + L G+ G Sbjct: 53 PERFNVFKYNVRRIHESNKMDKPYKLKVNEFADMTNLEFVNTYANSKISHFQALRGSAPG 112 Query: 65 GPNLPERVGF--SEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRIC 122 + F + +P+ D RE+ + ++ QG CGSCWAF AV A+ Sbjct: 113 SIDTDPNKDFIYANVTKIPDKVDWREK----NAVTDVKGQGGCGSCWAFAAVVALEGINA 168 Query: 123 IHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPY 182 I T V+ S + L+ C GC+GG A+ + + G ++ PY Sbjct: 169 IRTGKL--VKFSEQQLVDCDMT--NAGCDGGLMEPAFTYVIKHGGIA------PEASYPY 218 Query: 183 TIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAE 242 + +G +V ++E + + Sbjct: 219 VGKRETCDKAKIKDVLKIDGRQ--------------------------NVPGLDEEALRK 252 Query: 243 IYKNGPVEGAFTVFSD-FLTYKSGVYKHEAGDVMGGHAIRILGWG-IENGVPYWLVANSW 300 + PV + Y GVY + G H + I+G+G E G+ +W V NSW Sbjct: 253 AVAHQPVATGIQLSGHGLQFYSEGVYTGDCGTEP-NHGVGIVGYGENEKGIKFWTVKNSW 311 Query: 301 NVDWGDNGFFKILRG---ENHCGIESEIVAGI 329 WG+ G+ + RG E CG+ I Sbjct: 312 GPTWGEKGYIHLQRGARKEGLCGVAMHSSFPI 343 >3P5W-A nrPDB Length = 220 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 108/256 (42%), Gaps = 44/256 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+ D W + + I+DQG CGSCWAF + A+ I T + +S ++L+ Sbjct: 1 LPDYVD----WRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDL--ISLSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GC+GG+ + + F G ++ PYT + +++ Sbjct: 55 DCGRTQNTRGCDGGFMTDGFQFIINNGGIN------TEANYPYTAEEGQCNLD------- 101 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSEKEIMAEIYKNGPVEGAFTVFS- 257 +++K+ +Y +V + + + PV A Sbjct: 102 -------------------LQQEKYVSIDTYENVPYNNEWALQTAVAYQPVSVALEAAGY 142 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--- 314 +F Y SG++ G + HA+ I+G+G E G+ YW+V NSW WG+ G+ +I R Sbjct: 143 NFQHYSSGIFTGPCGTAV-DHAVTIVGYGTEGGIDYWIVKNSWGTTWGEEGYMRIQRNVG 201 Query: 315 GENHCGIESEIVAGIP 330 G CGI + + Sbjct: 202 GVGQCGIAKKASYPVK 217 >1NB3-A nrPDB Length = 220 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 110/256 (42%), Gaps = 41/256 (16%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P S D R++ + ++ +++QGSCGSCW F A+ + I T + ++ + L+ Sbjct: 2 PPSMDWRKKGN---FVSPVKNQGSCGSCWTFSTTGALESAVAIATGKM--LSLAEQQLVD 56 Query: 141 CCGIQCGDGCNGGYPSGAWNFW-TRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC GG PS A+ + KG++ Y P Sbjct: 57 CAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTY-----------------------PYK 93 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 G+ D K + + E+ ++ + PV AF V +DF Sbjct: 94 GQDDHCKFQPDKAIAFVKDVANITM---------NDEEAMVEAVALYNPVSFAFEVTNDF 144 Query: 260 LTYKSGVYKHEAGDVMG---GHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE 316 L Y+ G+Y + HA+ +G+G ENG+PYW+V NSW WG NG+F I RG+ Sbjct: 145 LMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGK 204 Query: 317 NHCGIESEIVAGIPRT 332 N CG+ + IP Sbjct: 205 NMCGLAACASYPIPLV 220 >4YYR-A nrPDB Length = 222 Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 71/259 (27%), Positives = 108/259 (41%), Gaps = 43/259 (16%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R Q + + IR+QG CGSCWAF V + I T+ + +S + L+ Sbjct: 1 LPETVDWRIQGA----VNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPS--LSEQQLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC+GG+ + A+++ + G ++ PYT E Sbjct: 55 DCATSYKNLGCSGGWMTKAYDYIIKNGGITSQS------NYPYTAKKGE----------- 97 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-SD 258 CNK + + +H V + + + N PV Sbjct: 98 -------CNKDLASQIVATIDSYEH-------VPRNNENALKNAVANQPVSVTIEAGGRA 143 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG--- 315 F YKSGV+ G + HA+ +G+G EN V YWLV NSW +WG+ G+ K+ R Sbjct: 144 FELYKSGVFVGSCGTKL-DHAVVAIGYGSENDVDYWLVRNSWGTNWGERGYIKLQRNVAE 202 Query: 316 -ENHCGIESEIVAGIPRTQ 333 CGI + + +T Sbjct: 203 PTGKCGIAMQSTYPVKKTS 221 >3KFQ-A nrPDB Length = 221 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 69/258 (26%), Positives = 107/258 (41%), Gaps = 48/258 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+S D R++ + +++Q CGSCWAF A A+ ++ T V +S ++L+ Sbjct: 1 LPKSVDWRKKGY----VTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL--VSLSEQNLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPP--CEHHVNGSRPP 197 C Q GCNGG+ + A+ + G + PY C++ S Sbjct: 55 DCSRPQGNQGCNGGFMARAFQYVKENGGLDS------EESYPYVAVDEICKYRPENSVAQ 108 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-F 256 TG + EK +M + GP+ A Sbjct: 109 DTGF---------------------------TVVAPGKEKALMKAVATVGPISVAMDAGH 141 Query: 257 SDFLTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNVDWGDNGFFK 311 S F YKSG+Y + + H + ++G+G E + YWLV NSW +WG NG+ K Sbjct: 142 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDNSKYWLVKNSWGPEWGSNGYVK 201 Query: 312 ILRGE-NHCGIESEIVAG 328 I + + NHCGI + Sbjct: 202 IAKDKNNHCGIATAASYP 219 >4P6E-A nrPDB Length = 230 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 70/255 (27%), Positives = 111/255 (43%), Gaps = 46/255 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP+S D RE+ + +++ QGSCG+CWAF AV A+ ++ + T V +SA++L+ Sbjct: 7 LPDSVDWREKG----CVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKL--VSLSAQNLV 60 Query: 140 TCCGIQCGD-GCNGGYPSGAWNFWTRK-GLVSGGVYNSHIGCLPYTI--PPCEHHVNGSR 195 C + G+ GCNGG+ + A+ + G+ S Y PY C++ Sbjct: 61 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 113 Query: 196 PPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV 255 C+ + P E + + GPV Sbjct: 114 ATCSKYTELPYGR---------------------------EDVLKEAVANKGPVSVGVDA 146 Query: 256 -FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 F Y+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 147 RHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 206 Query: 315 GE-NHCGIESEIVAG 328 + NHCGI S Sbjct: 207 NKGNHCGIASFPSYP 221 >2FO5-A nrPDB Length = 262 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 63/262 (24%), Positives = 99/262 (37%), Gaps = 42/262 (16%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 +LP S D R++ + ++DQG CGSCWAF V ++ I T V +S ++L Sbjct: 3 DLPPSVDWRQKGAVTG----VKDQGKCGSCWAFSTVVSVEGINAIRTGSL--VSLSEQEL 56 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C DGC GG A+ + G + PY Sbjct: 57 IDCDTAD-NDGCQGGLMDNAFEYIKNNGGL------ITEAAYPYRAARG----------- 98 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-S 257 C + + V + +E +A N PV A Sbjct: 99 -----------TCNVARAAQNSPVVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGK 147 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGI-ENGVPYWLVANSWNVDWGDNGFFKILRGE 316 F+ Y GV+ E G + H + ++G+G+ E+G YW V NSW WG+ G+ ++ + Sbjct: 148 AFMFYSEGVFTGECGTEL-DHGVAVVGYGVAEDGKAYWTVKNSWGPSWGEQGYIRVEKDS 206 Query: 317 ----NHCGIESEIVAGIPRTQQ 334 CGI E + + Sbjct: 207 GASGGLCGIAMEASYPVKTYSK 228 >4BS5-A nrPDB Length = 225 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 107/255 (41%), Gaps = 45/255 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP++ D RE+ + +++ QGSCG+CWAF AV A+ ++ + T + +SA++L+ Sbjct: 8 LPDTVDWREKG----CVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKL--ISLSAQNLV 61 Query: 140 TCCGIQ--CGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTI--PPCEHHVNGSR 195 C + GC GGY + A+ + G + PY C ++ Sbjct: 62 DCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEAD------ASYPYKAMDEKCHYNSKNRA 115 Query: 196 PPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV 255 C+ P E + + GPV Sbjct: 116 ATCSRYIQLPF---------------------------GDEDALKEAVATKGPVSVGIDA 148 Query: 256 -FSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 S F YKSGVY + H + ++G+G +G YWLV NSW +++GD G+ ++ R Sbjct: 149 SHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMAR 208 Query: 315 -GENHCGIESEIVAG 328 +NHCGI S Sbjct: 209 NNKNHCGIASYCSYP 223 >1AEC-A nrPDB Length = 218 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 107/256 (41%), Gaps = 44/256 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D W + + I+ QG CG CWAF A+ + I T V + +S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTG--VLISLSEQELI 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GCNGGY + + F G ++ PYT E +V+ Sbjct: 55 DCGRTQNTRGCNGGYITDGFQFIINNGGIN------TEENYPYTAQDGECNVD------- 101 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 + +K+ +Y +V + + + PV A D Sbjct: 102 -------------------LQNEKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--- 314 F Y SG++ G + HA+ I+G+G E G+ YW+V NSW+ WG+ G+ +ILR Sbjct: 143 AFKQYSSGIFTGPCGTAI-DHAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GENHCGIESEIVAGIP 330 G CGI + + Sbjct: 202 GAGTCGIATMPSYPVK 217 >2VHS-A nrPDB Length = 217 Score = 224 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 69/254 (27%), Positives = 105/254 (41%), Gaps = 42/254 (16%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 P S D RE+ + +++QG CG+ +AF A A+ ++ T + +S ++L+ Sbjct: 1 APRSVDWREKGY----VTPVKNQGQCGASYAFSATGALEGQMFRKTGRL--ISLSEQNLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C G Q +GCNGG A+ + G G+ + T C+++ S Sbjct: 55 DCSGPQGNEGCNGGLMDYAFQYVQDNG----GLDSEESYPYEATEESCKYNPKYSVANDV 110 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSD 258 G D PK EK +M + GP+ A Sbjct: 111 GFVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHES 142 Query: 259 FLTYKSGVY-KHEAGDVMGGHAIRILGWG-IENGVPYWLVANSWNVDWGDNGFFKILRG- 315 FL YK G+Y + HA+ ++G+G I N YWLV NSW +WG G+ K+ + Sbjct: 143 FLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKYWLVKNSWGEEWGMGGYVKMAKDR 202 Query: 316 ENHCGIESEIVAGI 329 NHCGI S Sbjct: 203 RNHCGIASAASYPT 216 >5JA7-A nrPDB Length = 223 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 112/257 (43%), Gaps = 46/257 (17%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 P+S D R++ + +++QG CGS WAF +V A+ ++ T +N +S ++L Sbjct: 8 RAPDSVDYRKKGY----VTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLN--LSPQNL 61 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRK-GLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197 + C + DGC GGY + A+ + + G+ S Y C ++ G Sbjct: 62 VDC--VSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVG-----QEESCMYNPTGKAAK 114 Query: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF- 256 C G + P+ N EK + + + GPV A Sbjct: 115 CRGYREIPEGN---------------------------EKALKRAVARVGPVSVAIDASL 147 Query: 257 SDFLTYKSGVYK-HEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG 315 + F Y GVY HA+ +G+GI+ G +W++ NSW +WG+ G+ + R Sbjct: 148 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 207 Query: 316 ENH-CGIESEIVAGIPR 331 +N+ CGI + +A P+ Sbjct: 208 KNNACGIAN--LASFPK 222 >1CQD-A nrPDB Length = 221 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 60/258 (23%), Positives = 104/258 (40%), Gaps = 46/258 (17%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 +LP+S D RE + P +++QG CGSCWAF V A+ I T + +S + L Sbjct: 2 DLPDSIDWRENGAVVP----VKNQGGCGSCWAFSTVAAVEGINQIVTGDL--ISLSEQQL 55 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C GC GG+ + A+ F G ++ PY + + P Sbjct: 56 VDCTTA--NHGCRGGWMNPAFQFIVNNGGINS------EETYPYRGQDGICNSTVNAPVV 107 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-S 257 + + +V ++ + + N PV Sbjct: 108 SIDSYE--------------------------NVPSHNEQSLQKAVANQPVSVTMDAAGR 141 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG-- 315 DF Y+SG++ ++ HA+ ++G+G EN +W+V NSW +WG++G+ + R Sbjct: 142 DFQLYRSGIFTGSC-NISANHALTVVGYGTENDKDFWIVKNSWGKNWGESGYIRAERNIE 200 Query: 316 --ENHCGIESEIVAGIPR 331 + CGI + + Sbjct: 201 NPDGKCGITRFASYPVKK 218 >3BCN-A nrPDB Length = 209 Score = 222 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 58/253 (22%), Positives = 87/253 (34%), Gaps = 48/253 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE D R + + + +++QG CGSCWAF V + I T + +S + L+ Sbjct: 1 LPEHVDWRAKGA----VIPLKNQGKCGSCWAFSTVTTVESINQIRTGNL--ISLSEQQLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GGY A+ + G + PY Sbjct: 55 DCS--KKNHGCKGGYFDRAYQYIIANGGID------TEANYPYKAFQGPCRAAKKVVRID 106 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 G P+CN E + + V F Sbjct: 107 GCKGVPQCN---------------------------ENALKNAVASQPSVVAIDASSKQF 139 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--GEN 317 YK G++ G + H + I+G+G YW+V NSW WG+ G+ ++ R G Sbjct: 140 QHYKGGIFTGPCGTKL-NHGVVIVGYG----KDYWIVRNSWGRHWGEQGYTRMKRVGGCG 194 Query: 318 HCGIESEIVAGIP 330 CGI Sbjct: 195 LCGIARLPFYPTK 207 >4YYW-A nrPDB Length = 220 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 102/257 (39%), Gaps = 45/257 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R + + + IRDQG CGSCW F + + I T+ + +S ++LL Sbjct: 1 LPETVDWRSKGA----VDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPS--LSEQELL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWT-RKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 C GC GG+ A+++ +G+ S Y PYT Sbjct: 55 DCAPSYKDLGCKGGWMDKAYDYIIKDRGITSESDY-------PYTARKGACDSR------ 101 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 E + V ++ + + N PV A S Sbjct: 102 -------------------KATEVVATISSYEDVPADNEDALKKAVANQPVSVAIDASSA 142 Query: 259 -FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 Y SGV+ G V HA+ ++G+G E+GV YWLV NSW WG+ G+ K+ R Sbjct: 143 AVKEYSSGVFVGSCG-VANDHAVVVVGYGTESGVNYWLVRNSWGTKWGEEGYMKLERDTA 201 Query: 318 H----CGIESEIVAGIP 330 H CGI E + Sbjct: 202 HPAGKCGIAMESTYPVK 218 >2PNS-A nrPDB Length = 208 Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 57/253 (22%), Positives = 86/253 (33%), Gaps = 48/253 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE D R++ + + +++QG CGSCWAF V + I T + +S + L+ Sbjct: 1 LPEQIDWRKKGA----VTPVKNQGKCGSCWAFSTVSTVESINQIRTGNL--ISLSEQQLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GG A+ + G + PY Sbjct: 55 DC--NKKNHGCKGGAFVYAYQYIIDNGGID------TEANYPYKAVQGPCRAAKKVVRID 106 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 G P CN E + + V F Sbjct: 107 GYKGVPHCN---------------------------ENALKKAVASQPSVVAIDASSKQF 139 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--GEN 317 YKSG++ G + H + I+G+ YW+V NSW WG+ G+ ++ R G Sbjct: 140 QHYKSGIFSGPCGTKL-NHGVVIVGYW----KDYWIVRNSWGRYWGEQGYIRMKRVGGCG 194 Query: 318 HCGIESEIVAGIP 330 CGI Sbjct: 195 LCGIARLPYYPTK 207 >2ACT-A nrPDB Length = 220 Score = 220 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 105/256 (41%), Gaps = 44/256 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D W + + I+ QG CG CWAF A+ + I + + +S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSL--ISLSEQELI 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C Q GC+GGY + + F G ++ PYT + V Sbjct: 55 DCGRTQNTRGCDGGYITDGFQFIINDGGIN------TEENYPYTAQDGDCDV-------- 100 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSY-SVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 + ++ K+ +Y +V + + + PV A D Sbjct: 101 ------------------ALQDQKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--- 314 F Y SG++ G + HAI I+G+G E GV YW+V NSW+ WG+ G+ +ILR Sbjct: 143 AFKQYASGIFTGPCGTAV-DHAIVIVGYGTEGGVDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GENHCGIESEIVAGIP 330 G CGI + + Sbjct: 202 GAGTCGIATMPSYPVK 217 >6BKI-A nrPDB Length = 215 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 61/255 (23%), Positives = 110/255 (43%), Gaps = 44/255 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P+S D R++ + +++QG CGSCWAF + A+ ++ T + +S ++L+ Sbjct: 1 VPDSIDYRKKGY----VTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKL--LALSPQNLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GGY + A+ + + G G+ + C ++ C Sbjct: 55 DC--VTENYGCGGGYMTTAFQYVQQNG----GIDSEDAYPYVGQDESCMYNAAAKAAKCR 108 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-SD 258 G + P N EK + + + GP+ + + Sbjct: 109 GYREIPVGN---------------------------EKALKRAVARVGPISVSIDASLAS 141 Query: 259 FLTYKSGVYKHEAGDVMG-GHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 F Y GVY E D HA+ ++G+G + G +W++ NSW WG+ G+ + R +N Sbjct: 142 FQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKN 201 Query: 318 H-CGIESEIVAGIPR 331 + CGI + +A P+ Sbjct: 202 NACGITN--MASFPK 214 >1IWD-A nrPDB Length = 215 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 57/256 (22%), Positives = 92/256 (35%), Gaps = 47/256 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D R + + + I++Q CGSCWAF AV A+ I T + +S ++L+ Sbjct: 1 LPSFVDWRSKGA----VNSIKNQKQCGSCWAFSAVAAVESINKIRTGQL--ISLSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GCNGG+ + A+ + G + PY+ Sbjct: 55 DCDTA--SHGCNGGWMNNAFQYIITNGGID------TQQNYPYSAVQGSCK--------- 97 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS-D 258 Y+ V+ + + + + PV Sbjct: 98 ------------------PYRLRVVSINGFQRVTRNNESALQSAVASQPVSVTVEAAGAP 139 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG--- 315 F Y SG++ G H + I+G+G ++G YW+V NSW +WG+ G+ + R Sbjct: 140 FQHYSSGIFTGPCGTA-QNHGVVIVGYGTQSGKNYWIVRNSWGQNWGNQGYIWMERNVAS 198 Query: 316 -ENHCGIESEIVAGIP 330 CGI Sbjct: 199 SAGLCGIAQLPSYPTK 214 >1O0E-A nrPDB Length = 208 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 59/254 (23%), Positives = 90/254 (35%), Gaps = 50/254 (19%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE D R++ + + +++QGSCGSCWAF V + I T + +S ++L+ Sbjct: 1 LPEQIDWRKKGA----VTPVKNQGSCGSCWAFSTVSTVESINQIRTGNL--ISLSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GG A+ + G + PY Sbjct: 55 DCD--KKNHGCLGGAFVFAYQYIINNGGID------TQANYPYKAVQGPCQAASKVVSID 106 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD- 258 G P CN + + + P A S Sbjct: 107 GYNGVPFCN----------------------------EXALKQAVAVQPSTVAIDASSAQ 138 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR--GE 316 F Y SG++ G + H + I+G+ YW+V NSW WG+ G+ ++LR G Sbjct: 139 FQQYSSGIFSGPCGTKL-NHGVTIVGYQ----ANYWIVRNSWGRYWGEKGYIRMLRVGGC 193 Query: 317 NHCGIESEIVAGIP 330 CGI Sbjct: 194 GLCGIARLPYYPTK 207 >1YAL-A nrPDB Length = 218 Score = 215 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 102/256 (39%), Gaps = 46/256 (17%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 P+S D R + + + +++QG+CGSCWAF + + I T +E+S ++L+ Sbjct: 2 PQSIDWRAKGA----VTPVKNQGACGSCWAFSTIATVEGINKIVTGNL--LELSEQELVD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C + GC GGY + + + G+ + VY PY + P Sbjct: 56 CD--KHSYGCKGGYQTTSLQYVANNGVHTSKVY-------PYQAKQYKCRATDKPGP--- 103 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 259 T YK TS+ + N P+ F Sbjct: 104 ------------KVKITGYKRVPSNCETSFLGA----------LANQPLSVLVEAGGKPF 141 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 YKSGV+ G + HA+ +G+G +G Y ++ NSW +WG+ G+ ++ R Sbjct: 142 QLYKSGVFDGPCGTKL-DHAVTAVGYGTSDGKNYIIIKNSWGPNWGEKGYMRLKRQSG-- 198 Query: 320 GIESEIVAGIPRTQQY 335 S+ G+ ++ Y Sbjct: 199 --NSQGTCGVYKSSYY 212 >3F75-A nrPDB Length = 224 Score = 212 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 53/256 (20%), Positives = 85/256 (33%), Gaps = 41/256 (16%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP A W + + ++DQ CGSCWAF A+ C T V +S ++L+ Sbjct: 3 LPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKL--VSLSEQELM 60 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + C+GG + A+ + G + PY E Sbjct: 61 DCSRAEGNQSCSGGEMNDAFQYVLDSGGICSED------AYPYLARDEECRAQSCEKVVK 114 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS-D 258 G V + M PV A Sbjct: 115 ILGFK--------------------------DVPRRSEAAMKAALAKSPVSIAIEADQMP 148 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGI--ENGVPYWLVANSWNVDWGDNGFFKILR-- 314 F Y GV+ G + H + ++G+G E+ +W++ NSW WG +G+ + Sbjct: 149 FQFYHEGVFDASCGTDL-DHGVLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYMYMAMHK 207 Query: 315 -GENHCGIESEIVAGI 329 E CG+ + + Sbjct: 208 GEEGQCGLLLDASFPV 223 >1PPO-A nrPDB Length = 216 Score = 210 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 99/256 (38%), Gaps = 44/256 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R++ + + +R QGSCGSCWAF AV + I T VE+S ++L+ Sbjct: 1 LPENVDWRKKGA----VTPVRHQGSCGSCWAFSAVATVEGINKIRTGKL--VELSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GC GGYP A + + G+ Y PY P Sbjct: 55 DC--ERRSHGCKGGYPPYALEYVAKNGIHLRSKY-------PYKAKQGTCRAKQVGGPIV 105 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 + ++E ++ I K + F Sbjct: 106 KTSGVGRVQ------------------------PNNEGNLLNAIAKQPVSVVVESKGRPF 141 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 YK G+++ G + HA+ +G+G G Y L+ NSW WG+ G+ +I R Sbjct: 142 QLYKGGIFEGPCGTKV-DHAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAPG-- 198 Query: 320 GIESEIVAGIPRTQQY 335 S V G+ ++ Y Sbjct: 199 --NSPGVCGLYKSSYY 212 >6MIS-A nrPDB Length = 215 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 101/255 (39%), Gaps = 47/255 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P+S D R+ + + +++QG CGSCWAF ++ + I V +S + +L Sbjct: 1 VPQSIDWRDSGA----VTSVKNQGRCGSCWAFASIATVESIYKIKRGNL--VSLSEQQVL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC GG+ + A++F V+ PY NG Sbjct: 55 DCAV---SYGCKGGWINKAYSFIISNKGVASAAI------YPYKAAKGTCKTNG------ 99 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 + +Y ++E+ +M + N P+ A +F Sbjct: 100 -------------------VPNSAYITRYTYVQRNNERNMMYAV-SNQPIAAALDASGNF 139 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWG-IENGVPYWLVANSWNVDWGDNGFFKILRGE-- 316 YK GV+ G + HAI I+G+G +G +W+V NSW WG+ G+ ++ R Sbjct: 140 QHYKRGVFTGPCGTRL-NHAIVIIGYGQDSSGKKFWIVRNSWGAGWGEGGYIRLARDVSS 198 Query: 317 --NHCGIESEIVAGI 329 CGI + + Sbjct: 199 SFGLCGIAMDPLYPT 213 >2BDZ-A nrPDB Length = 214 Score = 207 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 62/255 (24%), Positives = 98/255 (38%), Gaps = 50/255 (19%) Query: 81 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 PES D RE+ + + +++Q CGSCWAF V + I T + +S ++LL Sbjct: 2 PESIDWREKGA----VTPVKNQNPCGSCWAFSTVATIEGINKIITGQL--ISLSEQELLD 55 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C + GC+GGY + + + G+ + Y PY + P Sbjct: 56 C--ERRSHGCDGGYQTTSLQYVVDNGVHTEREY-------PYEKKQGRCRAKDKKGP--- 103 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 259 Y T YK V +++ + + N PV F Sbjct: 104 ------------KVYITGYKY----------VPANDEISLIQAIANQPVSVVTDSRGRGF 141 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENH- 318 YK G+Y+ G HA+ +G+G Y L+ NSW +WG+ G+ +I R Sbjct: 142 QFYKGGIYEGPCGT-NTDHAVTAVGYG----KTYLLLKNSWGPNWGEKGYIRIKRASGRS 196 Query: 319 ---CGIESEIVAGIP 330 CG+ + I Sbjct: 197 KGTCGVYTSSFFPIK 211 >2CIO-A nrPDB Length = 212 Score = 205 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 97/256 (37%), Gaps = 50/256 (19%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +PE D R++ + + +++QGSCGSCWAF AV + I I T S ++LL Sbjct: 1 IPEYVDWRQKGA----VTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQ--YSEQELL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + GCNGGYP A + G+ Y G + C Sbjct: 55 DCD--RRSYGCNGGYPWSALQLVAQYGIHYRNTYPYE----------------GVQRYCR 96 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-SD 258 P K Y + + N PV D Sbjct: 97 SREKGPYAAKTDGVRQVQPY----------------NEGALLYSIANQPVSVVLEAAGKD 140 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENH 318 F Y+ G++ G+ + HA+ +G+G Y L+ NSW WG+NG+ +I RG + Sbjct: 141 FQLYRGGIFVGPCGNKV-DHAVAAVGYG----PNYILIKNSWGTGWGENGYIRIKRGTGN 195 Query: 319 ----CGIESEIVAGIP 330 CG+ + + Sbjct: 196 SYGVCGLYTSSFYPVK 211 >6EXO-A nrPDB Length = 215 Score = 204 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 61/250 (24%), Positives = 106/250 (42%), Gaps = 37/250 (14%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 P + D RE+ + + ++DQG CGSCWAF + + + + N V +S + L+ Sbjct: 1 APAAVDWREKGA----VTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPL--VSLSEQMLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 +C I GC GG A+N+ S G PY + Sbjct: 55 SCDTIDF--GCGGGLMDNAFNWIVN----SNGGNVFTEASYPYV---------------S 93 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 G G+ P+C G+ H + E I A + +NGP+ A F Sbjct: 94 GNGEQPQCQMN---GHEIGAAITDHV-----DLPQDEDAIAAYLAENGPLAIAVDAT-SF 144 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 + Y G+ + + H + ++G+ + PYW++ NSW+ WG++G+ +I +G N C Sbjct: 145 MDYNGGILTSCTSEQL-DHGVLLVGYNDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQC 203 Query: 320 GIESEIVAGI 329 + + + + Sbjct: 204 LMNQAVSSAV 213 >5A24-A nrPDB Length = 222 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 61/254 (24%), Positives = 94/254 (37%), Gaps = 41/254 (16%) Query: 84 FDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCG 143 A W + +++Q CG CWAF AV A+ I T +S E ++ C Sbjct: 1 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTL--TSLSEEQIVDCDT 58 Query: 144 IQCGDGCNGGYPSGAWNFWTRK-GLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEG 202 GCNGG P GA+ + G+ + Y PYT GS C+ Sbjct: 59 NGNDKGCNGGTPDGAFQYVVNNQGIDTESDY-------PYTAG------GGSPGTCSASS 105 Query: 203 DTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS-DFLT 261 P + V + ++ + + P+ A F + Sbjct: 106 YQPAASIT-----------------GYQDVPANNEQALQQAAATQPISVAIDASDPSFQS 148 Query: 262 YKSGVYKHEAGDVMGGHAIRILGWGIE--NGVPYWLVANSWNVDWGDNGFFKILRGENH- 318 Y SG+Y + HA+ ++G+G + +G YW+V NSW WG G+ + G N Sbjct: 149 YSSGIYSGPCNTNL-DHAVTVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQMGLNAP 207 Query: 319 ---CGIESEIVAGI 329 CGI + Sbjct: 208 YGVCGIAMQASYPT 221 >4YYQ-A nrPDB Length = 217 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 45/257 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPE+ D R + + + IR+QG CGSCWAF AV A+ I T +++ Sbjct: 1 LPETVDWRSKGA----VNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLL-- 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GC GG+ + A+ + + ++ PYT + Sbjct: 55 DCAQSYKNLGCQGGWVNKAFEYIIQNRGITSQS------NYPYTGHKGQ----------- 97 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF-SD 258 C G ++ D + V + + + N PV A Sbjct: 98 -----------CRTGLASIATIDSY-----QYVPSNNENALKNAVANQPVSVAVEAAGRA 141 Query: 259 FLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRG--- 315 F YKSGV+ G V HA+ ++G+G NGV YWL+ NSW +WG+ G+ K+ R Sbjct: 142 FQLYKSGVFTGSCG-VAIDHAVVLIGYGKYNGVDYWLLRNSWGTNWGEQGYMKLQRNVAQ 200 Query: 316 -ENHCGIESEIVAGIPR 331 CG+ + + Sbjct: 201 SAGKCGVARLCLYPVKC 217 >4PI3-A nrPDB Length = 216 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 113/250 (45%), Gaps = 37/250 (14%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 P + D R + + + ++DQG CGSCWAF A+ + + + + N +S + L+ Sbjct: 2 APAAVDWRARGA----VTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTN--LSEQMLV 55 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 +C GC+GG + A+ + ++ +G VY S P + Sbjct: 56 SCDKTD--SGCSGGLMNNAFEWIVQEN--NGAVYTED-----------------SYPYAS 94 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 GEG +P C +G++ H + E +I A + NGPV A S + Sbjct: 95 GEGISPPCT---TSGHTVGATITGHV-----ELPQDEAQIAAWLAVNGPVAVAVDA-SSW 145 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 +TY GV + + H + ++G+ VPYW++ NSW WG+ G+ +I +G N C Sbjct: 146 MTYTGGVMTSCVSEQL-DHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQC 204 Query: 320 GIESEIVAGI 329 ++ E + + Sbjct: 205 LVKEEASSAV 214 >2B1M-A nrPDB Length = 246 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 56/257 (21%), Positives = 94/257 (36%), Gaps = 40/257 (15%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 + PES+D ++ I +++ QG CGS WAF A A+ I T V +S ++L Sbjct: 1 DAPESWDWSKKG----VITKVKFQGQCGSGWAFSATGAIEAAHAIATGNL--VSLSEQEL 54 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C + +GC G+ ++ + + G ++ PY + N + Sbjct: 55 IDC--VDESEGCYNGWHYQSFEWVVKHGGIASEAD------YPYKARDGKCKANEIQDKV 106 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 T + + P+ + D Sbjct: 107 TIDNYGVQILSNESTESEAESSLQSFVLE-------------------QPISVSIDA-KD 146 Query: 259 FLTYKSGVYKHEAGDVM--GGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE 316 F Y G+Y H + I+G+G E+GV YW+ NSW DWG +G+ +I R Sbjct: 147 FHFYSGGIYDGGNCSSPYGINHFVLIVGYGSEDGVDYWIAKNSWGEDWGIDGYIRIQRNT 206 Query: 317 NH----CGIESEIVAGI 329 + CG+ I Sbjct: 207 GNLLGVCGMNYFASYPI 223 >1GEC-E nrPDB Length = 216 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 63/256 (24%), Positives = 96/256 (37%), Gaps = 44/256 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LPES D R + + + ++ QG C SCWAF V + I T VE+S ++L+ Sbjct: 1 LPESVDWRAKGA----VTPVKHQGYCESCWAFSTVATVEGINKIKTGNL--VELSEQELV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GCN GY S + + + G+ Y PY N P Sbjct: 55 DCDLQ--SYGCNRGYQSTSLQYVAQNGIHLRAKY-------PYIAKQQTCRANQVGGPKV 105 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 + ++E ++ I + DF Sbjct: 106 KTNGVGRVQS------------------------NNEGSLLNAIAHQPVSVVVESAGRDF 141 Query: 260 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHC 319 YK G+++ G + HA+ +G+G G Y L+ NSW WG+NG+ +I R Sbjct: 142 QNYKGGIFEGSCGTKV-DHAVTAVGYGKSGGKGYILIKNSWGPGWGENGYIRIRRASG-- 198 Query: 320 GIESEIVAGIPRTQQY 335 S V G+ R+ Y Sbjct: 199 --NSPGVCGVYRSSYY 212 >5VPK-A nrPDB Length = 223 Score = 194 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 61/250 (24%), Positives = 93/250 (37%), Gaps = 40/250 (16%) Query: 76 EDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSA 135 +N+P D R + T+ IR QG CGSCWAF V A + N ++++S Sbjct: 7 NSVNVPSELDLR----SLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRN--TSLDLSE 60 Query: 136 EDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSR 195 ++L+ C GC+G + + G+V Y PY + Sbjct: 61 QELVDCASQ---HGCHGDTIPRGIEYIQQNGVVEERSY-------PYVAREQQC------ 104 Query: 196 PPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV 255 P + Y Y D +E + + + V Sbjct: 105 -------RRPNSQHYGISNYCQIYPPDV----------KQIREALTQTHTAIAVIIGIKD 147 Query: 256 FSDFLTYKS-GVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 F Y + +H+ G HA+ I+G+G GV YW+V NSW+ WGD+G+ Sbjct: 148 LRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGVDYWIVRNSWDTTWGDSGYGYFQA 207 Query: 315 GENHCGIESE 324 G N IE Sbjct: 208 GNNLMMIEQY 217 >3BPF-A nrPDB Length = 241 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 62/267 (23%), Positives = 106/267 (39%), Gaps = 55/267 (20%) Query: 82 ESFD-AREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 140 E+FD A W + ++DQ +CGSCWAF ++ ++ + I N + +S ++L+ Sbjct: 15 ENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLIT--LSEQELVD 72 Query: 141 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 C GCNGG + A+ G + ++ P Sbjct: 73 CS--FKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRC----------- 119 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFL 260 + YG +Y K + + GP+ + V DF Sbjct: 120 ---------------------TEKYGIKNYLSVPDNK-LKEALRFLGPISISVAVSDDFA 157 Query: 261 TYKSGVYKHEAGDVMGGHAIRILGWGIENGVP----------YWLVANSWNVDWGDNGFF 310 YK G++ E GD + HA+ ++G+G++ V Y+++ NSW WG+ GF Sbjct: 158 FYKEGIFDGECGDQL-NHAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFI 216 Query: 311 KILRGEN----HCGIESEIVAGIPRTQ 333 I E+ CG+ ++ A IP + Sbjct: 217 NIETDESGLMRKCGLGTD--AFIPLIE 241 >1DEU-A nrPDB Length = 277 Score = 190 bits (483), Expect = 5e-49, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 29/259 (11%) Query: 63 LGGPNLPERVGFSEDINLPESFDAR-EQWSNCPTIAQIRDQ---GSCGSCWAFGAVEAMS 118 LG P + +LP+S+D R N +I R+Q CGSCWA + AM+ Sbjct: 19 LGRTTYPRPHEYLSPADLPKSWDWRNVDGVNYASIT--RNQHIPQYCGSCWAHASTSAMA 76 Query: 119 DRICIHTNGR-VNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHI 177 DRI I G + +S ++++ C C GG W++ + G+ Sbjct: 77 DRINIKRKGAWPSTLLSVQNVIDCG---NAGSCEGGNDLSVWDYAHQHGIPDE------- 126 Query: 178 GCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEK 237 ++ C CN+ E +Y + Y S S + Sbjct: 127 ---------TCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLS---GRE 174 Query: 238 EIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVA 297 ++MAEIY NGP+ Y G+Y H + + GWGI +G YW+V Sbjct: 175 KMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVR 234 Query: 298 NSWNVDWGDNGFFKILRGE 316 NSW WG+ G+ +I+ Sbjct: 235 NSWGEPWGERGWLRIVTST 253 >3IOQ-A nrPDB Length = 213 Score = 190 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 57/257 (22%), Positives = 93/257 (36%), Gaps = 52/257 (20%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 +P S D R++ + + +R+QG CGSCW F +V A+ I T +++ Sbjct: 1 IPTSIDWRQKGA----VTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELL-- 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEH-HVNGSRPPC 198 C + GC GG+P A + G+ Y C G + Sbjct: 55 DC--ERRSYGCRGGFPLYALQYVANSGIHLRQYYPYEG-----VQRQCRASQAKGPKVKT 107 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FS 257 G G P+ N ++ + + PV Sbjct: 108 DGVGRVPRNN----------------------------EQALIQRIAIQPVSIVVEAKGR 139 Query: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 F Y+ G++ G + HA+ +G+G Y L+ NSW WG+ G+ +I RG Sbjct: 140 AFQNYRGGIFAGPCGTSI-DHAVAAVGYGN----DYILIKNSWGTGWGEGGYIRIKRGSG 194 Query: 318 H----CGIESEIVAGIP 330 + CG+ S+ V Sbjct: 195 NPQGACGVLSDSVFPTK 211 >3BPM-A nrPDB Length = 243 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 56/257 (21%), Positives = 96/257 (37%), Gaps = 52/257 (20%) Query: 87 REQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQC 146 W + ++DQ CGSCWAF +V ++ + I S ++L+ C Sbjct: 23 AYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKAL--FLFSEQELVDCSV--K 78 Query: 147 GDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPK 206 +GC GGY + A++ G + ++ LP T + + Sbjct: 79 NNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETC------------------NLKR 120 Query: 207 CNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGV 266 CN+ S +DK + GP+ + DF Y+ G Sbjct: 121 CNERYTIKSYVSIPDDKF---------------KEALRYLGPISISIAASDDFAFYRGGF 165 Query: 267 YKHEAGDVMGGHAIRILGWGIEN----------GVPYWLVANSWNVDWGDNGFFKILRGE 316 Y E G HA+ ++G+G+++ Y+++ NSW DWG+ G+ + E Sbjct: 166 YDGECG-AAPNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDE 224 Query: 317 N----HCGIESEIVAGI 329 N C I +E + Sbjct: 225 NGYKKTCSIGTEAYVPL 241 >1ICF-A nrPDB Length = 175 Score = 188 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 54/212 (25%), Positives = 86/212 (40%), Gaps = 40/212 (18%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 P S D RE+ + +++QG CGSCWAF A A+ ++ T + +S ++L+ Sbjct: 1 APRSVDWREKGY----VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRL--ISLSEQNLV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C G Q +GCNGG A+ + G G+ + T C+++ S T Sbjct: 55 DCSGPQGNEGCNGGLMDYAFQYVQDNG----GLDSEESYPYEATEESCKYNPKYSVANDT 110 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSD 258 G D PK EK +M + GP+ A Sbjct: 111 GFVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHES 142 Query: 259 FLTYKSGVY-KHEAGDVMGGHAIRILGWGIEN 289 FL YK G+Y + + H + ++G+G E+ Sbjct: 143 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 174 >1XKG-A nrPDB Length = 312 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 57/331 (17%), Positives = 110/331 (33%), Gaps = 51/331 (15%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKK---LC 59 + + + + D+ ++ + + + + A + ++ + K + Sbjct: 8 FEEYKKAFNKSYATFEDEEAAR---KNFLESVKYVQSNGGAINHLSDLSLDEFKNRFLMS 64 Query: 60 GTVLGGPNLPERVGFSEDI-----NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAV 114 + + N P D R+ T+ IR QG CGS WAF V Sbjct: 65 AEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQM----RTVTPIRMQGGCGSAWAFSGV 120 Query: 115 EAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYN 174 A + + +++++ ++L+ C GC+G + G+V Y Sbjct: 121 AATESAYLAYRD--QSLDLAEQELVDCASQ---HGCHGDTIPRGIEYIQHNGVVQESYYR 175 Query: 175 SHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSD 234 Y P + + Y Y + ++ Sbjct: 176 -------YVAREQSC-------------RRPNAQRFGISNYCQIYPPN----------AN 205 Query: 235 SEKEIMAEIYKNGPVEGAFTVFSDFLTYKS-GVYKHEAGDVMGGHAIRILGWGIENGVPY 293 +E +A+ + V F Y + + + G HA+ I+G+ GV Y Sbjct: 206 KIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDY 265 Query: 294 WLVANSWNVDWGDNGFFKILRGENHCGIESE 324 W+V NSW+ +WGDNG+ + IE Sbjct: 266 WIVRNSWDTNWGDNGYGYFAANIDLMMIEEY 296 >5VCN-A nrPDB Length = 222 Score = 184 bits (466), Expect = 5e-47, Method: Composition-based stats. Identities = 56/247 (22%), Positives = 90/247 (36%), Gaps = 40/247 (16%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 N P D R+ T+ IR QG CGSCWAF V A + N +++++ ++L Sbjct: 9 NAPAEIDLRQM----RTVTPIRMQGGCGSCWAFSGVAATESAYLAYRN--QSLDLAEQEL 62 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPC 198 + C GC+G + G+V Y Y Sbjct: 63 VDCASQ---HGCHGDTIPRGIEYIQHNGVVQESYYR-------YVAREQSC--------- 103 Query: 199 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD 258 P + + Y Y + ++ +E +A+ + V Sbjct: 104 ----RRPNAQRFGISNYCQIYPPN----------ANKIREALAQTHSAIAVIIGIKDLDA 149 Query: 259 FLTYKS-GVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317 F Y + + + G HA+ I+G+ GV YW+V NSW+ +WGDNG+ + Sbjct: 150 FRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANID 209 Query: 318 HCGIESE 324 IE Sbjct: 210 LMMIEEY 216 >3U8E-A nrPDB Length = 222 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 56/263 (21%), Positives = 92/263 (34%), Gaps = 50/263 (19%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 P S D R++ + + ++DQG+CG CWAFGA A+ I T + VS + ++ Sbjct: 1 APASIDWRKKGA----VTSVKDQGACGMCWAFGATGAIEGIDAITTGRL--ISVSEQQIV 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C GG A+ + G ++ PYT +N Sbjct: 55 DCDTXXXXX--XGGDADDAFRWVITNGGIASD------ANYPYTGVDGTCDLN------- 99 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 K +V +S ++ + K +T + F Sbjct: 100 --------------------KPIAARIDGYTNVPNSSSALLDAVAKQPVSVNIYTSSTSF 139 Query: 260 LTYKS-GVYKHEAGDVMG---GHAIRILGWGIEN-GVPYWLVANSWNVDWGDNGFFKILR 314 Y G++ + H + I+G+G YW+V NSW +WG +G+ I R Sbjct: 140 QLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNADYWIVKNSWGTEWGIDGYILIRR 199 Query: 315 GENH----CGIESEIVAGIPRTQ 333 N C I++ T Sbjct: 200 NTNRPDGVCAIDAWGSYPTKSTS 222 >1M6D-A nrPDB Length = 214 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 59/253 (23%), Positives = 107/253 (42%), Gaps = 44/253 (17%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 P +D R + + + +++DQG CGSCWAF + + + N + +S ++LL Sbjct: 1 APPEWDWRSKGA----VTKVKDQGMCGSCWAFSVTGNVEGQWFL--NQGTLLSLSEQELL 54 Query: 140 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCT 199 C + C GG PS A++ G + ++ G C Sbjct: 55 DCDKMDKA--CMGGLPSNAYSAIKNLGGLE---------------TEDDYSYQGHMQSC- 96 Query: 200 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 259 S ++ K Y S +S +E+++ A + K GP+ A F Sbjct: 97 ----------------QFSAEKAKVYIQDSVELSQNEQKLAAWLAKRGPISVAINAFG-M 139 Query: 260 LTYKSGV---YKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE 316 Y+ G+ + + HA+ ++G+G + VP+W + NSW DWG+ G++ + RG Sbjct: 140 QFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPFWAIKNSWGTDWGEKGYYYLHRGS 199 Query: 317 NHCGIESEIVAGI 329 CG+ + + + Sbjct: 200 GACGVNTMASSAV 212 >1EF7-A nrPDB Length = 242 Score = 173 bits (438), Expect = 9e-44, Method: Composition-based stats. Identities = 64/242 (26%), Positives = 98/242 (40%), Gaps = 29/242 (11%) Query: 80 LPESFDAR-EQWSNCPTIAQIRDQ---GSCGSCWAFGAVEAMSDRICIHTNGR-VNVEVS 134 LP+S+D R N +I R+Q CGSCWA + AM+DRI I G + +S Sbjct: 1 LPKSWDWRNVDGVNYASIT--RNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLS 58 Query: 135 AEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGS 194 ++++ C C GG W++ + G+ ++ Sbjct: 59 VQNVIDCG---NAGSCEGGNDLSVWDYAHQHGIPDE----------------TCNNYQAK 99 Query: 195 RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFT 254 C CN+ E +Y + Y S S +++MAEIY NGP+ Sbjct: 100 DQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLS---GREKMMAEIYANGPISCGIM 156 Query: 255 VFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILR 314 Y G+Y H + + GWGI +G YW+V NSW WG+ G+ +I+ Sbjct: 157 ATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVT 216 Query: 315 GE 316 Sbjct: 217 ST 218 >5JT8-A nrPDB Length = 333 Score = 170 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 79/344 (22%), Positives = 138/344 (40%), Gaps = 56/344 (16%) Query: 3 WSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNT--TWQAGRNFYNVDISYLKK--- 57 + +A ++ + + ++ + N + N Y+ D+S + Sbjct: 28 FEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHNGIDGVEYAINEYS-DMSEQEFSFH 86 Query: 58 -----LCGTVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFG 112 L T + E + + +LP++FD R++ + +IR QGSCGSCWAF Sbjct: 87 LSGGGLNFTYMKMEAAKEPLINTYG-SLPQNFDWRQKAR----LTRIRQQGSCGSCWAFA 141 Query: 113 AVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCG-----DGCNGGYPSGAWNFWTRKGL 167 A I + ++E+S ++L+ C + +GC GY + A+ + R GL Sbjct: 142 AAGVAESLYSIQK--QQSIELSEQELVDCTYNRYDPSYQCNGCGSGYSTEAFKYMIRTGL 199 Query: 168 VSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGY 227 V Y ++ C+ V G R +G Y Sbjct: 200 VEERNYPYNMRT-----QWCDPDVEGQRYHVSG--------------------------Y 228 Query: 228 TSYSVSDSEKEIMAEIYKNGPVEGAFTVFSD-FLTYKSGVYKHEA-GDVMGGHAIRILGW 285 S++++M I ++GPV ++ F +GV + A D HA+ ++GW Sbjct: 229 QQLRYHSSDEDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGW 288 Query: 286 GIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGI 329 G GV YW++ NSW WG+ G+ + RG N GI + + Sbjct: 289 GTVQGVDYWIIRNSWGTGWGNGGYGYVERGHNSLGINNYVTYAT 332 >3CH2-X nrPDB Length = 265 Score = 166 bits (421), Expect = 9e-42, Method: Composition-based stats. Identities = 59/239 (24%), Positives = 94/239 (39%), Gaps = 18/239 (7%) Query: 91 SNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGC 150 +NC + Q+ DQG+C + W F + + C+ G ++SA + C + D C Sbjct: 16 NNCISNLQVEDQGNCDTSWIFASKYHLETIRCMK--GYEPTKISALYVANCYKGEHKDRC 73 Query: 151 N-GGYPSGAWNFWTRKG-LVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCN 208 + G P G L + Y + + P E H + + N Sbjct: 74 DEGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPN 133 Query: 209 KMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYK 268 + GY+ E H ++ K I E+ G V A+ + + Y+ K Sbjct: 134 SLDGKGYTAYESERFHDNMDAFV-----KIIKTEVMNKGSV-IAYIKAENVMGYEFSGKK 187 Query: 269 HE--AGDVMGGHAIRILGWGIE-----NGVPYWLVANSWNVDWGDNGFFKI-LRGENHC 319 + GD HA+ I+G+G YW+V NSW WGD G+FK+ + G HC Sbjct: 188 VQNLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >4OEL-A nrPDB Length = 370 Score = 156 bits (393), Expect = 2e-38, Method: Composition-based stats. Identities = 67/249 (26%), Positives = 107/249 (42%), Gaps = 39/249 (15%) Query: 29 DMINYINKQNTTWQAG--RNFYNVDISYLKKLCGTVLGGPNLPERVGFSEDI-----NLP 81 + + IN +W A + + + + + G P+ + +I +LP Sbjct: 149 NFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLP 208 Query: 82 ESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTC 141 S+D R ++ +R+Q SCGSC++F ++ + RI I TN +S +++++C Sbjct: 209 TSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 267 Query: 142 CGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTG 200 Q GC GG+P A + GLV C PYT G+ PC Sbjct: 268 S--QYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT---------GTDSPCKM 309 Query: 201 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFL 260 + D C YS+ Y HY Y + E + E+ +GP+ AF V+ DFL Sbjct: 310 KED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAFEVYDDFL 357 Query: 261 TYKSGVYKH 269 YK G+Y H Sbjct: 358 HYKKGIYHH 366 >4CDF-B nrPDB Length = 166 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 60/193 (31%), Positives = 90/193 (46%), Gaps = 32/193 (16%) Query: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137 ++LP S+D R ++ +R+Q SCGSC++F ++ + RI I TN +S ++ Sbjct: 1 LHLPTSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQE 59 Query: 138 LLTCCGIQCGDGCNGGYPSG-AWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRP 196 +++C Q GC GG+P A + GLV C PYT G+ Sbjct: 60 VVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT---------GTDS 101 Query: 197 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 PC + D C YS+ Y HY Y + E + E+ +GP+ AF V+ Sbjct: 102 PCKMKED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAFEVY 149 Query: 257 SDFLTYKSGVYKH 269 DFL YK G+Y H Sbjct: 150 DDFLHYKKGIYHH 162 >5I4H-B nrPDB Length = 112 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 7/107 (6%) Query: 230 YSVSDSEKEIMAEIYKNGPVEGAFTV-FSDFLTYKSGVY-KHEAGDVMGGHAIRILGWGI 287 + EK +M + GP+ A FL YK G+Y + + H + ++G+G Sbjct: 5 VDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGF 64 Query: 288 E----NGVPYWLVANSWNVDWGDNGFFKILRG-ENHCGIESEIVAGI 329 E + YWLV NSW +WG G+ K+ + NHCGI S Sbjct: 65 ESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 111 >5I4H-A nrPDB Length = 106 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 10/116 (8%) Query: 79 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138 P S D RE+ + +++QG CGS WAF A A+ ++ T + +S ++L Sbjct: 1 EAPRSVDWREKGY----VTPVKNQGQCGSSWAFSATGALEGQMFRKTGRL--ISLSEQNL 54 Query: 139 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGS 194 + C G Q +GCNGG A+ + G G+ + T C+++ S Sbjct: 55 VDCSGPQGNEGCNGGLMDYAFQYVQDNG----GLDSEESYPYEATEESCKYNPKYS 106 >4OEM-B nrPDB Length = 70 Score = 98.0 bits (242), Expect = 5e-21, Method: Composition-based stats. Identities = 26/59 (44%), Positives = 39/59 (66%), Gaps = 2/59 (3%) Query: 274 VMGGHAIRILGWGIEN--GVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGIP 330 + HA+ ++G+G ++ G+ YW+V NSW WG+NG+F+I RG + C IES VA P Sbjct: 7 ELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATP 65 >4CI7-A nrPDB Length = 470 Score = 67.9 bits (164), Expect = 6e-12, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 68/235 (28%), Gaps = 44/235 (18%) Query: 94 PTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGG 153 ++QGS + W+F + + + + G ++S E L Sbjct: 75 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLK--GYGTYDLSEEHL--------------- 117 Query: 154 YPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEA 213 + +GG Y ++ + + + E D P K Sbjct: 118 -----------RWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQ 166 Query: 214 GYSTSYKED----KHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKH 269 G + D + ++ ++ + I + G V + +S + Y Sbjct: 167 GATKPSNMDTAPTQFNVTDVVRLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNC 226 Query: 270 EAGDVMGGHAIRILGWGIENGVP------------YWLVANSWNVDWGDNGFFKI 312 HA+ I+GW WLV +SW GFF I Sbjct: 227 TNKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 281 >4D59-A nrPDB Length = 406 Score = 67.6 bits (163), Expect = 8e-12, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 68/235 (28%), Gaps = 44/235 (18%) Query: 94 PTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGG 153 ++QGS + W+F + + + + G ++S E L Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLK--GYGTYDLSEEHL--------------- 53 Query: 154 YPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEA 213 + +GG Y ++ + + + E D P K Sbjct: 54 -----------RWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQ 102 Query: 214 GYSTSYKED----KHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKH 269 G + D + ++ ++ + I + G V + +S + Y Sbjct: 103 GATKPSNMDTAPTQFNVTDVVRLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNC 162 Query: 270 EAGDVMGGHAIRILGWGIENGVP------------YWLVANSWNVDWGDNGFFKI 312 HA+ I+GW WLV +SW GFF I Sbjct: 163 TNKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 217 >3OIS-A nrPDB Length = 291 Score = 59.8 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 45/242 (18%), Positives = 85/242 (35%), Gaps = 38/242 (15%) Query: 80 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 139 LP D + Q+ DQG GSC A A+ + + + E L Sbjct: 57 LPPKVDLTPPF-------QVYDQGRIGSCTANALAAAIQ---FERIHDKQSPEFIPSRLF 106 Query: 140 TCCGIQCGDGC----NGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSR 195 + +G +G + G+ PY G Sbjct: 107 IYYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPE-------KEWPY----------GDT 149 Query: 196 PPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYS-VSDSEKEIMAEIYKNGPVEGAFT 254 P + P + YK+ ++Y T YS V+ + A + P F+ Sbjct: 150 PADPRTEEFPPGAPASKKPSDQCYKDAQNYKITEYSRVAQDIDHLKACLAVGSPFVFGFS 209 Query: 255 VFSDFLTYKSGVYKHE----AGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFF 310 V++ ++ S + + GGHA+ +G+ ++ + ++ + NSW + G++G+F Sbjct: 210 VYNSWVGNNSLPVRIPLPTKNDTLEGGHAVLCVGY--DDEIRHFRIRNSWGNNVGEDGYF 267 Query: 311 KI 312 + Sbjct: 268 WM 269 >4K7C-A nrPDB Length = 446 Score = 45.2 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 272 GDVMGGHAIRILGWGIENGVPY-WLVANSWNVDWGDNGFF 310 G+ + HA+ + G + +G P W V NSW G+ G+F Sbjct: 358 GESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 11/26 (42%) Query: 99 IRDQGSCGSCWAFGAVEAMSDRICIH 124 + +Q G CW F A+ M I Sbjct: 61 VSNQKQSGRCWMFAALNTMRHGIQAQ 86 >5WDK-A nrPDB Length = 401 Score = 37.9 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 17/35 (48%), Gaps = 1/35 (2%) Query: 270 EAGDVMGGHAIRILGWGIEN-GVPYWLVANSWNVD 303 + + H ++I G + G Y++V NSW + Sbjct: 328 DNYETTDDHGMQIYGIAKDQEGNEYYMVKNSWGTN 362 Score = 35.2 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 6/37 (16%), Positives = 16/37 (43%) Query: 96 IAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVE 132 I +++Q G+CW + + + + G ++ Sbjct: 40 ITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLS 76 >2CB5-A nrPDB Length = 453 Score = 36.4 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 18/45 (40%), Gaps = 4/45 (8%) Query: 272 GDVMGGHAIRILGWGIENGVP----YWLVANSWNVDWGDNGFFKI 312 G+ + HA+ ++ W V NSW D G G+ + Sbjct: 365 GESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >2EKL-A nrPDB Length = 313 Score = 31.7 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 39/120 (32%), Gaps = 1/120 (0%) Query: 182 YTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMA 241 Y I ++ + + +E + + + Sbjct: 47 YDIIVVRSRTKVTKDVIEKGKKLKIIARAGIGLDNIDTEEAEKRNIKVVYAPGASTDSAV 106 Query: 242 EIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWN 301 E+ + A +++ KSG++K G + G I I+G+G G ++AN+ Sbjct: 107 ELTIGLMIAAARKMYTSMALAKSGIFKKIEGLELAGKTIGIVGFGRI-GTKVGIIANAMG 165 >3OME-A nrPDB Length = 282 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 15/51 (29%), Gaps = 5/51 (9%) Query: 64 GGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGS-----CW 109 G + F D +W N P + QG C S CW Sbjct: 90 GEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLCW 140 >2Z51-A nrPDB Length = 154 Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 6/15 (40%), Positives = 11/15 (73%) Query: 94 PTIAQIRDQGSCGSC 108 + +++ QG+CGSC Sbjct: 34 GNVVRVKLQGACGSC 48 >5O4O-C nrPDB Length = 649 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 31/82 (37%), Gaps = 14/82 (17%) Query: 82 ESFDAREQWSNCPTIAQIRDQG-SC--------GSCWAFGA--VEAMSDRICIHTNGRVN 130 ++ D R+ + ++D G SC G CW G+ + ++ IC Sbjct: 159 DTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHC 218 Query: 131 VEVSAEDLLTCCGIQCGDGCNG 152 + CC +C GC+G Sbjct: 219 FGPNPNQ---CCHDECAGGCSG 237 >3LY6-A nrPDB Length = 697 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 14/33 (42%), Gaps = 5/33 (15%) Query: 83 SFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVE 115 S D +W N +++ G CW F AV Sbjct: 257 SVDILRRWKNHGC-QRVKY----GQCWVFAAVA 284 >3P11-A nrPDB Length = 522 Score = 28.6 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 31/82 (37%), Gaps = 14/82 (17%) Query: 82 ESFDAREQWSNCPTIAQIRDQG-SC--------GSCWAFGA--VEAMSDRICIHTNGRVN 130 ++ D R+ + ++D G SC G CW G+ + ++ IC Sbjct: 140 DTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHC 199 Query: 131 VEVSAEDLLTCCGIQCGDGCNG 152 + CC +C GC+G Sbjct: 200 FGPNPNQ---CCHDECAGGCSG 218 >5Y34-A nrPDB Length = 596 Score = 27.5 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 17/40 (42%), Gaps = 5/40 (12%) Query: 85 DAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIH 124 D R+ W+ I + C C A +V A+ D + I Sbjct: 64 DPRDAWAFVERICGV-----CTGCHALASVRAVEDALDIK 98 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.120 0.379 Lambda K H 0.267 0.0371 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,765,328 Number of Sequences: 36641 Number of extensions: 584561 Number of successful extensions: 1890 Number of sequences better than 10.0: 90 Number of HSP's better than 10.0 without gapping: 160 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1190 Number of HSP's gapped (non-prelim): 238 length of query: 339 length of database: 10,336,785 effective HSP length: 98 effective length of query: 241 effective length of database: 6,745,967 effective search space: 1625778047 effective search space used: 1625778047 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.5 bits)