BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00560 (416 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1QPG-A nrPDB 830 0.0 1FW8-A nrPDB 684 0.0 5NP8-A nrPDB 544 e-155 2PAA-A nrPDB 522 e-148 3OZ7-A nrPDB 508 e-144 1HDI-A nrPDB 506 e-144 1VPE-A nrPDB 385 e-107 3UWD-A nrPDB 379 e-105 1PHP-A nrPDB 376 e-105 3ZLB-A nrPDB 344 5e-95 3Q3V-A nrPDB 338 2e-93 16PK-A nrPDB 330 7e-91 4DG5-A nrPDB 329 1e-90 4EHJ-A nrPDB 308 3e-84 4NG4-A nrPDB 305 3e-83 1V6S-A nrPDB 278 2e-75 5BT8-A nrPDB 264 7e-71 1ZMR-A nrPDB 256 1e-68 2CUN-A nrPDB 199 2e-51 2IZ1-A nrPDB 35 0.060 2ZYA-A nrPDB 34 0.12 2W8Z-A nrPDB 29 3.3 3SEZ-A nrPDB 29 3.7 5H3C-A nrPDB 29 3.9 6O4N-A nrPDB 28 9.1 >1QPG-A nrPDB Length = 415 Score = 830 bits (2145), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/415 (99%), Positives = 415/415 (100%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA Sbjct: 1 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 60 Query: 62 SHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL 121 SHLG+PNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL Sbjct: 61 SHLGQPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL 120 Query: 122 RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQ 181 RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQ Sbjct: 121 RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQ 180 Query: 182 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 241 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT Sbjct: 181 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 240 Query: 242 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 301 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD Sbjct: 241 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 300 Query: 302 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 361 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS Sbjct: 301 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 360 Query: 362 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK Sbjct: 361 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 415 >1FW8-A nrPDB Length = 416 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/343 (100%), Positives = 343/343 (100%) Query: 74 KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV 133 KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV Sbjct: 3 KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV 62 Query: 134 DGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELK 193 DGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELK Sbjct: 63 DGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELK 122 Query: 194 YFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGD 253 YFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGD Sbjct: 123 YFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGD 182 Query: 254 SIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLD 313 SIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLD Sbjct: 183 SIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLD 242 Query: 314 NGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGD 373 NGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGD Sbjct: 243 NGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGD 302 Query: 374 TATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 TATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK Sbjct: 303 TATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 345 Score = 151 bits (381), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 71/71 (100%), Positives = 71/71 (100%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA Sbjct: 346 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 405 Query: 62 SHLGRPNGERN 72 SHLGRPNGERN Sbjct: 406 SHLGRPNGERN 416 >5NP8-A nrPDB Length = 420 Score = 544 bits (1402), Expect = e-155, Method: Compositional matrix adjust. Identities = 273/415 (65%), Positives = 321/415 (77%), Gaps = 2/415 (0%) Query: 1 MSLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVL 60 MSLS+KL++ LD+K KRV +RVDFNVP+ +IT+NQRI AA+P+IK+ L++ + VVL Sbjct: 4 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 63 Query: 61 ASHLGRPNG-ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLE 119 SHLGRP+G +KYSL PVA EL+SLLGKDV FL DCVGPEVE A A GSVILLE Sbjct: 64 MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 123 Query: 120 NLRYHIEEEGSRK-VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD 178 NLR+H+EEEG K G KVKA ++ FR LS L DVY+NDAFGTAHRAHSSMVG + Sbjct: 124 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 183 Query: 179 LPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGM 238 LPQ+A GFL++KEL YF KALE+P RPFLAILGGAKVADKIQLI+N+LDKV+ +IIGGGM Sbjct: 184 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 243 Query: 239 AFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKT 298 AFTF KVL N EIG S+FD+ GA+IV LM KA+ GV++ LPVDF+ AD F +A T Sbjct: 244 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 303 Query: 299 VTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVV 358 T GIPAGW GLD GPES K +A V +AK IVWNGP GVFE+E FA GTKAL+DEVV Sbjct: 304 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 363 Query: 359 KSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLS 413 K+++ G IIGGGDTAT K+ DK+SHVSTGGGASLELLEGK LPGV LS Sbjct: 364 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALS 418 >2PAA-A nrPDB Length = 416 Score = 522 bits (1344), Expect = e-148, Method: Compositional matrix adjust. Identities = 261/414 (63%), Positives = 318/414 (76%), Gaps = 2/414 (0%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 +LS+KL++ +DLK KRV +RVDFNVP+ +IT+NQRI AA+P+IK+ L++ + VVL Sbjct: 1 ALSAKLTLDKVDLKGKRVIMRVDFNVPMKNNQITNNQRIKAAIPSIKHCLDNGAKSVVLM 60 Query: 62 SHLGRPNG-ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLEN 120 SHLGRP+G +KYSL PVA EL+SLL KDV FL DCVGPEVE A GS+ILLEN Sbjct: 61 SHLGRPDGIPMPDKYSLEPVADELKSLLNKDVIFLKDCVGPEVEQACANPDNGSIILLEN 120 Query: 121 LRYHIEEEGSRK-VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDL 179 LR+H+EEEG K G+K+ A V+ FR LS L DVY+NDAFGTAHRAHSSMVG +L Sbjct: 121 LRFHVEEEGKGKDSSGKKISADPAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNL 180 Query: 180 PQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA 239 PQ+A+GFL++KEL YF KALE P RPFLAILGGAKV DKIQLI N+LDKV+ +IIGGGMA Sbjct: 181 PQKASGFLMKKELDYFSKALEKPERPFLAILGGAKVKDKIQLIKNMLDKVNFMIIGGGMA 240 Query: 240 FTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTV 299 +TF K L+N +IG S+FD+ GA IV ++MEKA+ GV++V PVDF+ D F +A Sbjct: 241 YTFLKELKNMQIGASLFDEEGATIVKEIMEKAEKNGVKIVFPVDFVTGDKFDENAKVGQA 300 Query: 300 TDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVK 359 T + GIP+GW GLD GPES K+ A VA+AK IVWNGP GVFE++ FA GTKAL+DEVVK Sbjct: 301 TIESGIPSGWMGLDCGPESIKINAQIVAQAKLIVWNGPIGVFEWDAFAKGTKALMDEVVK 360 Query: 360 SSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLS 413 +++ G IIGGGDTAT K+G DK+SHVSTGGGASLELLEGK LPGV LS Sbjct: 361 ATSNGCVTIIGGGDTATCCAKWGTEDKVSHVSTGGGASLELLEGKILPGVEALS 414 >3OZ7-A nrPDB Length = 417 Score = 508 bits (1308), Expect = e-144, Method: Compositional matrix adjust. Identities = 254/414 (61%), Positives = 321/414 (77%), Gaps = 4/414 (0%) Query: 3 LSSKLSVQDL-DLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 L +KLS+ DL D+K+K+V +RVDFNVP++ I RI A LPTI ++ + ++L Sbjct: 4 LGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILI 63 Query: 62 SHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL 121 SH GRP+G RNEKY+L PVA+ L+ LLG++V FLNDCVG EVE + A+ SVILLENL Sbjct: 64 SHCGRPDGLRNEKYTLKPVAETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENL 123 Query: 122 RYHIEEEGSRKVD--GQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDL 179 R+HIEEEG + VD G KVKA+KEDV+KF+++L+ LADV+INDAFGTAHRAHSSMVG L Sbjct: 124 RFHIEEEG-KGVDANGNKVKANKEDVEKFQNDLTKLADVFINDAFGTAHRAHSSMVGVKL 182 Query: 180 PQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA 239 +A+GFL++KEL+YF KALENP RP LAILGGAKV+DKIQLI NLLDKVD +IIGGGMA Sbjct: 183 NVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMA 242 Query: 240 FTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTV 299 +TFKKVL N +IG S+FD+AG++IV ++MEKAKAK V++ LPVDF IAD F +ANTK V Sbjct: 243 YTFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFV 302 Query: 300 TDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVK 359 TD+EGIP W GLD GP+S + + + +KT++WNGP GVFE FA G+ L+ VV+ Sbjct: 303 TDEEGIPDNWMGLDAGPKSIENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVE 362 Query: 360 SSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLS 413 + G I+GGGDTA++ ++ ++ISHVSTGGGASLELLEGKELPGV LS Sbjct: 363 VTKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLELLEGKELPGVLALS 416 >1HDI-A nrPDB Length = 413 Score = 506 bits (1304), Expect = e-144, Method: Compositional matrix adjust. Identities = 254/412 (61%), Positives = 304/412 (73%), Gaps = 2/412 (0%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +KL++ L++K KRV +RVDFNVP+ +IT+N RI AA+P+IK+ L+ + VVL SHL Sbjct: 1 NKLTLDKLNVKGKRVVMRVDFNVPMAAAQITNNARIKAAVPSIKFCLDDGAKSVVLMSHL 60 Query: 65 GRPNGE-RNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRY 123 GRP+G +KYSL PVA EL+S LGK V FL DCVGP VE A A GSVILLENLR+ Sbjct: 61 GRPDGSPMPDKYSLQPVAAELKSALGKAVLFLKDCVGPAVEKACADPAAGSVILLENLRF 120 Query: 124 HIEEEGSRK-VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQR 182 H+EEEG K G K ++ FR LS+L DVY+NDAFGTAHRAHSSMVG +LP++ Sbjct: 121 HVEEEGKGKDASGNKAAGEPAKIKAFRASLSALGDVYVNDAFGTAHRAHSSMVGVNLPKK 180 Query: 183 AAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTF 242 A FL++KEL YF A E+P RPFLAILGGAKVADKIQLI+N+LDKV+ +IIGGGMAFTF Sbjct: 181 AGAFLMKKELNYFAAAAESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTF 240 Query: 243 KKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDK 302 KVL N EIG S+FD+AG +IV LM KA A GV++ LPVDF+ AD F A T Sbjct: 241 LKVLNNMEIGTSLFDEAGKKIVKNLMSKAAANGVKITLPVDFVTADKFDEQAKIGQATVA 300 Query: 303 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362 GIPAGW GLD GP+S ++ VA+AK IVWNGP GVFE+E FA GTKAL+DEVVK+++ Sbjct: 301 SGIPAGWMGLDCGPKSSAKYSEAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATS 360 Query: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSE 414 G IIGGGDTAT K+ D +SHVSTGGGASLELLEGK LPGV LS Sbjct: 361 RGCITIIGGGDTATCCAKWNTEDNVSHVSTGGGASLELLEGKVLPGVDALSN 412 >1VPE-A nrPDB Length = 398 Score = 385 bits (989), Expect = e-107, Method: Compositional matrix adjust. Identities = 208/412 (50%), Positives = 273/412 (66%), Gaps = 17/412 (4%) Query: 6 KLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLG 65 K++++D+DLK KRV +RVDFNVP+ + + RI AALPTIKY LE + V+L SHLG Sbjct: 2 KMTIRDVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAK-VILLSHLG 60 Query: 66 RPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHI 125 RP GE + ++SLAPVAK L LLGK+V F+ VG EV+ AV+ G V+LLEN R+H Sbjct: 61 RPKGEPSPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFH- 119 Query: 126 EEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAA 184 G K D ++ KF +SLAD+++NDAFGTAHRAH+S VG A Sbjct: 120 --PGETKND--------PELAKF---WASLADIHVNDAFGTAHRAHASNVGIAQFIPSVA 166 Query: 185 GFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKK 244 GFL+EKE+K+ K NP +P++ +LGGAKV+DKI +I NL++K D I+IGG M FTF K Sbjct: 167 GFLMEKEIKFLSKVTYNPEKPYVVVLGGAKVSDKIGVITNLMEKADRILIGGAMMFTFLK 226 Query: 245 VLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEG 304 L E+G S ++ ++ +L+EKAK KGVE+VLPVD +IA K V +G Sbjct: 227 AL-GKEVGSSRVEEDKIDLAKELVEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDDG 285 Query: 305 IPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAG 364 IP GW GLD GPE+ +LF ++ AKT+VWNGP GVFE + FA GTK + + + G Sbjct: 286 IPEGWMGLDIGPETIELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKG 345 Query: 365 NTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 ++GGGD+A K+G+ DK SHVSTGGGASLE LEGKELPG+A + KK Sbjct: 346 AITVVGGGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELPGIASMRIKK 397 >3UWD-A nrPDB Length = 394 Score = 379 bits (974), Expect = e-105, Method: Compositional matrix adjust. Identities = 205/412 (49%), Positives = 275/412 (66%), Gaps = 20/412 (4%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +K S++D+DLK KRVF RVDFNVP+ KIT RI AALPTI+Y++E + V+LASHL Sbjct: 2 NKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAK-VILASHL 60 Query: 65 GRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYH 124 GRP G+ E+ L PVA L LLGKDV ++ GP + V A G V++LEN+R++ Sbjct: 61 GRPKGQAVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFY 120 Query: 125 IEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRA 183 EE K D + E ++LAD+++NDAFG AHRAH+S G D Sbjct: 121 AGEE-------------KNDAE-LAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAV 166 Query: 184 AGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFK 243 +G L+EKEL+ GKAL NP RPF AI+GGAKV DKI LI +LLDKVD++IIGGG+A+TF Sbjct: 167 SGLLMEKELEVLGKALSNPERPFAAIIGGAKVKDKIGLIRHLLDKVDNLIIGGGLAYTFV 226 Query: 244 KVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKE 303 K L + EIG S+ + E+ + M+ AK KGV +PVD +I + FS A TK V + Sbjct: 227 KALGH-EIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIV-GID 284 Query: 304 GIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAA 363 IP+ W+G+D GP++R+++A + +K +VWNGP GVFE FA GTKA+ + + A Sbjct: 285 SIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQAL--ADAE 342 Query: 364 GNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 G +IGGGD+A +K+G+ DK+SH+STGGGASLE +EGKELPGV L++K Sbjct: 343 GTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK 394 >1PHP-A nrPDB Length = 394 Score = 376 bits (966), Expect = e-105, Method: Compositional matrix adjust. Identities = 209/413 (50%), Positives = 280/413 (67%), Gaps = 22/413 (5%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +K +++D+D++ KRVF RVDFNVP++ IT + RI AALPTI+Y++EH + V+LASHL Sbjct: 2 NKKTIRDVDVRGKRVFCRVDFNVPMEQGAITDDTRIRAALPTIRYLIEHGAK-VILASHL 60 Query: 65 GRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYH 124 GRP G+ E+ L VAK L LL + V N+ VG EV+AAV G V+LLEN+R++ Sbjct: 61 GRPKGKVVEELRLDAVAKRLGELLERPVAKTNEAVGDEVKAAVDRLNEGDVLLLENVRFY 120 Query: 125 IEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD--LPQR 182 EE K D + KA + LAD+Y+NDAFG AHRAH+S G LP Sbjct: 121 PGEE---KNDPELAKA-----------FAELADLYVNDAFGAAHRAHASTEGIAHYLPA- 165 Query: 183 AAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTF 242 AGFL+EKEL+ GKAL NP RPF AI+GGAKV DKI +IDNLL+KVD++IIGGG+A+TF Sbjct: 166 VAGFLMEKELEVLGKALSNPDRPFTAIIGGAKVKDKIGVIDNLLEKVDNLIIGGGLAYTF 225 Query: 243 KKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDK 302 K L + ++G S+ ++ E+ MEKAK KGV +PVD ++AD F+ DANTK V Sbjct: 226 VKALGH-DVGKSLLEEDKIELAKSFMEKAKEKGVRFYMPVDVVVADRFANDANTKVVP-I 283 Query: 303 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362 + IPA W LD GP++R+L+ + ++K +VWNGP GVFE + FA GTKA+ + A Sbjct: 284 DAIPADWSALDIGPKTRELYRDVIRESKLVVWNGPMGVFEMDAFAHGTKAI--AEALAEA 341 Query: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 +IGGGD+A +K+G+ DK+ H+STGGGASLE +EGK+LPGV L +K Sbjct: 342 LDTYSVIGGGDSAAAVEKFGLADKMDHISTGGGASLEFMEGKQLPGVVALEDK 394 >3ZLB-A nrPDB Length = 398 Score = 344 bits (882), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 201/415 (48%), Positives = 273/415 (65%), Gaps = 22/415 (5%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +KL+V+D+DLK K+V +RVDFNVPL IT++ RI AALPTIKY++E R +L SHL Sbjct: 2 AKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGR-AILFSHL 60 Query: 65 GRPNGERNEK-YSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRY 123 GR E ++ SLAPVA +L + LG+DV F G E+EAA+ A G V+L+EN RY Sbjct: 61 GRVKEESDKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEAAINALEDGQVLLVENTRY 120 Query: 124 HIEEEGSRKVDGQKVKASKEDVQKFRHELSSLAD-VYINDAFGTAHRAHSSMVGF--DLP 180 VDG+K + ++ K+ +SL D +++NDAFGTAHRAH+S VG ++ Sbjct: 121 E-------DVDGKKESKNDPELGKY---WASLGDGIFVNDAFGTAHRAHASNVGISANVE 170 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 + AGFLLE E+ Y +A+E P RPF+AILGG+KV+DKI +I+NLL+K D ++IGGGM + Sbjct: 171 KAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTY 230 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVT 300 TF K + EIG+S+ ++ ++ L+EKA K ++LPVD A+AF+ + T Sbjct: 231 TFYKA-QGIEIGNSLVEEDKLDVAKALLEKANGK---LILPVDSKEANAFAGYTEVRD-T 285 Query: 301 DKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKS 360 + E + G+ GLD GP+S F + AKT+VWNGP GVFE F AGT ++D +VK Sbjct: 286 EGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQ 345 Query: 361 SAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 G IIGGGD+A A G DK S +STGGGAS+ELLEGK LPG+A L+EK Sbjct: 346 P--GVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK 398 >3Q3V-A nrPDB Length = 403 Score = 338 bits (868), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 193/420 (45%), Positives = 267/420 (63%), Gaps = 26/420 (6%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDG-KKITSNQRIVAALPTIKYVLEHHPRYVVL 60 ++S +S++D+DL K+VFIR DFNVP D IT ++RI +A+PTI+Y L++ V+L Sbjct: 3 AMSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCS-VIL 61 Query: 61 ASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLEN 120 ASHLGRP E + KYSL PVAK L LL K++ D +G + + G ++LLEN Sbjct: 62 ASHLGRPK-EISSKYSLEPVAKRLARLLDKEIVMAKDVIGEDAKTKAMNLKAGEILLLEN 120 Query: 121 LRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVG---- 176 LR+ E+G K D + EL+S+ VYINDAFG HRAHSS+ Sbjct: 121 LRF---EKGETKND-----------ENLAKELASMVQVYINDAFGVCHRAHSSVEAITKF 166 Query: 177 FDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGG 236 FD + AGFLL+KE+ + +++P RPF+A++GG+KV+ K+Q + NLL KVD +IIGG Sbjct: 167 FDEKHKGAGFLLQKEIDFASNLIKHPARPFVAVVGGSKVSGKLQALTNLLPKVDKLIIGG 226 Query: 237 GMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANT 296 GMAFTF K L +IG+S+ ++ E K++ K K GV++ LPVD + A A S D Sbjct: 227 GMAFTFLKAL-GYDIGNSLLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPACSQDVPM 285 Query: 297 KTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDE 356 K V +E IP GW GLD GP S +LF ++ A+TI WNGP GVFE +KF+ G+ + Sbjct: 286 KFVPAQE-IPNGWMGLDIGPASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHY 344 Query: 357 VVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 + + A T ++GGGDTA V + G D+++ +STGGGASLEL+EGKELPGV L K+ Sbjct: 345 ISEGHA---TSVVGGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKE 401 >16PK-A nrPDB Length = 415 Score = 330 bits (846), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 190/429 (44%), Positives = 264/429 (61%), Gaps = 34/429 (7%) Query: 6 KLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLG 65 K S+ + DLK K+V IRVDFNVP+ KIT++ RI +ALPT+K VL VL SHLG Sbjct: 2 KKSINECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGS-CVLMSHLG 60 Query: 66 RPNG----------------ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKA 109 RP G +K +L PVAK L LL + VTF DC+ V Sbjct: 61 RPKGIPMAQAGKIRSTGGVPGFQQKATLKPVAKRLSELLLRPVTFAPDCL--NAADVVSK 118 Query: 110 SAPGSVILLENLRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHR 169 +PG V+LLEN+R++ +EEGS+K +D + L+S DVYI+DAFGTAHR Sbjct: 119 MSPGDVVLLENVRFY-KEEGSKKA---------KDREAMAKILASYGDVYISDAFGTAHR 168 Query: 170 AHSSMVGFD--LPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLD 227 ++M G L AAG+L+EKE+ YF K L NP RP +AI+GGAKV+DKIQL+DN+L Sbjct: 169 DSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQ 228 Query: 228 KVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIA 287 ++D ++IGG MA+TF K + IG S +++ E L++KA+ + V+V+LP+D + Sbjct: 229 RIDYLLIGGAMAYTFLKA-QGYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCH 287 Query: 288 DAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFA 347 F A ++ +T+ + IP G LD GP++ + + T+ K K+ +WNGP GVFE ++ Sbjct: 288 TEFKA-VDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYS 346 Query: 348 AGTKALLDEVVKSS-AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKEL 406 GT A+ + + + G IIGGGD+A+ A+ G ++SHVSTGGGASLELLEGK L Sbjct: 347 KGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTL 406 Query: 407 PGVAFLSEK 415 PGV L +K Sbjct: 407 PGVTVLDDK 415 >4DG5-A nrPDB Length = 403 Score = 329 bits (844), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 192/414 (46%), Positives = 264/414 (63%), Gaps = 20/414 (4%) Query: 4 SSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASH 63 S+K V DLDLK K V +R DFNVPL +IT++ RIV ALPTI+Y++E + +VL SH Sbjct: 8 SAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGK-IVLFSH 66 Query: 64 LGRPNGERNE-KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLR 122 LG+ E ++ K +L PVA++L L K+V F+ + G ++EAA+K G V+L+EN R Sbjct: 67 LGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTR 126 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLP-Q 181 Y +DG+K + ++ K+ +SL DV++NDAFGTAHR H+S VG + Sbjct: 127 Y-------EDLDGKKESKNDPELGKY---WASLGDVFVNDAFGTAHREHASNVGISTHLE 176 Query: 182 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 241 AAGFL++KE+K+ G + +P +P +AILGGAKV+DKI +I NL++ D IIIGGGMA+T Sbjct: 177 TAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYT 236 Query: 242 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 301 F K + EIG S+ ++ + L+EK G ++VLPVD +A FS DA TV Sbjct: 237 FLKA-QGKEIGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKI-TVVP 291 Query: 302 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 361 + IPA +G+D GP + KLFA + A T+VWNGP GVFEF FA GT + + Sbjct: 292 SDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLK 351 Query: 362 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 A IIGGGD+A A G + +H+STGGGASLE LEGKELPG+ ++ K Sbjct: 352 DA--ITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK 403 >4EHJ-A nrPDB Length = 392 Score = 308 bits (789), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 181/417 (43%), Positives = 266/417 (63%), Gaps = 35/417 (8%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 S L+++D+DLKDK+V +RVDFNVP+ K+TS RI AA+PTI+Y+L+ V+L SHL Sbjct: 2 SFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGA-VILMSHL 60 Query: 65 GRPN-GERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLR 122 GRP GE + ++SL PVAK L ++ K V F D + G +V+A G +++ EN+R Sbjct: 61 GRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKA-------GEIVMCENVR 113 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD--LP 180 ++ E K S +D+ K +++SL DV++ DAF TAHRA +S G +P Sbjct: 114 FNSGE-----------KKSTDDLSK---KIASLGDVFVMDAFATAHRAQASTYGVAKYIP 159 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 AG LL E++ KAL++P +P AI+GG+KV+ K+ +++NLLDKV+ +I+GGG+A Sbjct: 160 VACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIAN 219 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANT--KT 298 TF K E ++G+S++++ +++ KAKA GV + +PVD +A FS +A K Sbjct: 220 TFIKA-EGFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKK 278 Query: 299 VTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVV 358 V+D + A LD GPES+K+ A + A TI+WNGP GVFEF+ FA GTKAL + Sbjct: 279 VSD---VVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIA 335 Query: 359 KSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 +S A + GGGDT +K+G+ D++S++ST GGA LE LEGK+LP + L EK Sbjct: 336 QSHAFS---VAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEK 389 >4NG4-A nrPDB Length = 404 Score = 305 bits (780), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 175/413 (42%), Positives = 249/413 (60%), Gaps = 31/413 (7%) Query: 7 LSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGR 66 LS+ +L+L +KRV IR D NVP+ KIT+++RIV ALPTI+ +E R ++L SHLGR Sbjct: 15 LSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMIL-SHLGR 73 Query: 67 P-NGERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLRYH 124 P G+ +++SLAPVA+ L L + V +ND + G VE PG IL EN+R++ Sbjct: 74 PEEGKFEKEFSLAPVARLLSKKLNQKVPLINDWLKGVAVE-------PGQAILCENVRFN 126 Query: 125 IEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQR-- 182 K E+ + ++ L D+++ DAF TAHRA +S G + Sbjct: 127 --------------KGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKLA 172 Query: 183 AAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTF 242 AG LL E++ +ALENP +P +A++GG+KV+ KI L++NLLDKVD +I+GGG+A TF Sbjct: 173 CAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANTF 232 Query: 243 KKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDK 302 K + IG S+ + + + EKA K V + LPVD I+AD S DA TV + Sbjct: 233 LKA-QGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKA-TVKNI 290 Query: 303 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362 + + + D GP + +A +A+A TIVWNGP GVFE E F+ GT+AL V KS+A Sbjct: 291 DAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTA 350 Query: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 I+GGGDT K+ +TD++S+VST GGA LE LEGK LP + L+++ Sbjct: 351 YS---IVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGKILPAIKILTQR 400 >1V6S-A nrPDB Length = 390 Score = 278 bits (712), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 168/408 (41%), Positives = 245/408 (60%), Gaps = 25/408 (6%) Query: 8 SVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRP 67 ++ DLD K KRV +RVD+NVP+ K+ RI+ +LPT++++L V+L SHLGRP Sbjct: 3 TLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLAGGASLVLL-SHLGRP 61 Query: 68 NGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASA--PGSVILLENLRYHI 125 G + KYSLAPV + L++ L + F G E EA +A A PG V+LLEN+R+ Sbjct: 62 KGP-DPKYSLAPVGEALRAHL-PEARFAPFPPGSE-EARREAEALRPGEVLLLENVRF-- 116 Query: 126 EEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAA 184 E G K D + + L + ++ DAFG+AHRAH+S+VG L A Sbjct: 117 -EPGEEKND-----------PELSARYARLGEAFVLDAFGSAHRAHASVVGVARLLPAYA 164 Query: 185 GFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKK 244 GFL+EKE++ + L++P RP+ +LGGAKV+DKI +I++LL ++D ++IGG MAFTF K Sbjct: 165 GFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFTFLK 224 Query: 245 VLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEG 304 L E+G S+ ++ ++ L+ +A+A GV V LP D + A+ A T+ V Sbjct: 225 AL-GGEVGRSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVETR-VFPARA 282 Query: 305 IPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAG 364 IP + GLD GP++R+ FA + A+T+ WNGP GVFE F GT A+ + ++ G Sbjct: 283 IPVPYMGLDIGPKTREAFARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAI--AALEG 340 Query: 365 NTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFL 412 ++GGGD+ + G+ ++ HVSTGGGASLE LE LPG+ L Sbjct: 341 AFTVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFLEKGTLPGLEVL 388 >5BT8-A nrPDB Length = 403 Score = 264 bits (674), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 178/422 (42%), Positives = 237/422 (56%), Gaps = 48/422 (11%) Query: 9 VQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRP- 67 + DL+L KRV IR D NVP+ ITS+ R+ AALPTIK LE +V SHLGRP Sbjct: 14 MTDLNLAGKRVLIREDLNVPVKNGVITSDARLRAALPTIKAALEKGAAVMVF-SHLGRPV 72 Query: 68 NGERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLRYHIE 126 GE + SLAPVA L LG++V D + G EVEA G V+LLEN+R++ Sbjct: 73 EGEPKPEQSLAPVAAYLTEALGQEVKLFTDYLDGVEVEA-------GQVVLLENVRFNPG 125 Query: 127 EEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD--LPQRAA 184 E+ K + E QK+ ++L DV++ DAFGTAHRA +S G P AA Sbjct: 126 EK----------KNNPELAQKY----AALCDVFVMDAFGTAHRAEASTEGVARFAPVAAA 171 Query: 185 GFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKK 244 G LL EL G+A++ P +P +AI+ G+KV+ K+ ++++L D +I+GGG+A TF Sbjct: 172 GPLLAAELDALGRAMQTPEKPMVAIVAGSKVSTKLDVLNSLSGICDQLIVGGGIANTFLA 231 Query: 245 VLENTEIGDSIFDKAGAEIVPKLMEKAK--AKGVEVVLPVDFIIADAF---------SAD 293 +G S+++ L+E AK A V V LP D ++ADA S Sbjct: 232 A-AGYNVGKSLYEA-------DLVETAKQIAAKVSVPLPTDVVVADASQINFEDFLGSLA 283 Query: 294 ANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKAL 353 A + E + A LD GPE+ K FA + +KTI+WNGP GVFE ++F GTKAL Sbjct: 284 AAQAVIKKVEDVTANDMILDVGPETAKAFANILTTSKTILWNGPVGVFEVDQFGEGTKAL 343 Query: 354 LDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLS 413 V +S A I GGGDT KY V D+I ++STGGGA LE +EGK LP VA L Sbjct: 344 SLAVAQSDAFS---IAGGGDTLAAIDKYNVADQIGYISTGGGAFLEFVEGKTLPAVAVLL 400 Query: 414 EK 415 E+ Sbjct: 401 ER 402 >1ZMR-A nrPDB Length = 387 Score = 256 bits (655), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 166/417 (39%), Positives = 237/417 (56%), Gaps = 40/417 (9%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 S + + DLDL KRVFIR D NVP+ K+TS+ RI A+LPTI+ L+ + V++ SHL Sbjct: 2 SVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAK-VMVTSHL 60 Query: 65 GRPN-GERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLR 122 GRP GE NE++SL PV L+ L V + D + G +V A G +++LEN+R Sbjct: 61 GRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDV-------AEGELVVLENVR 113 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSM--VGFDLP 180 ++ K K+D + + ++L DV++ DAFGTAHRA +S +G Sbjct: 114 FN--------------KGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFAD 159 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 AG LL EL GKAL+ P RP +AI+GG+KV+ K+ ++D+L D +I+GGG+A Sbjct: 160 VACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIAN 219 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFS--ADANTKT 298 TF + ++G S+++ + +L+ + +P D +A FS A A K+ Sbjct: 220 TFIAA-QGHDVGKSLYEADLVDEAKRLLTTCN-----IPVPSDVRVATEFSETAPATLKS 273 Query: 299 VTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVV 358 V D + A Q LD G S + A + AKTI+WNGP GVFEF F GT+ + + + Sbjct: 274 VND---VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIA 330 Query: 359 KSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 S A I GGGDT +G+ DKIS++STGGGA LE +EGK LP VA L E+ Sbjct: 331 DSEAFS---IAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEER 384 >2CUN-A nrPDB Length = 410 Score = 199 bits (506), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 137/414 (33%), Positives = 218/414 (52%), Gaps = 35/414 (8%) Query: 7 LSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGR 66 ++D + +K VF+RVD N P+ KI S+ R A LPTI+Y++E + VV+ +H G+ Sbjct: 2 FRLEDFNFHNKTVFLRVDLNSPMKDGKIISDARFKAVLPTIRYLIESGAK-VVIGTHQGK 60 Query: 67 PNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIE 126 P E + + A+ L LL + V ++ D G +K G V +LENLR+ E Sbjct: 61 PYSE--DYTTTEEHARVLSELLDQHVEYIEDIFGRYAREKIKELKSGEVAILENLRFSAE 118 Query: 127 EEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAG 185 E ++ ++ + K + K +LS + D +NDAF TAHR+ S+VGF + G Sbjct: 119 EVKNKPIE----ECEKTFLVK---KLSKVIDYVVNDAFATAHRSQPSLVGFARIKPMIMG 171 Query: 186 FLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLL--DKVDSIIIGGGMA--FT 241 FL+EKE++ +A + P + +LGGAKV D +++++N+L ++ D ++ GG +A FT Sbjct: 172 FLMEKEIEALMRAYYSKDSPKIYVLGGAKVEDSLKVVENVLRRERADLVLTGGLVANVFT 231 Query: 242 FKKVLE----NTEI----GDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSAD 293 K + N E G + K EI+ + + PVDF + D Sbjct: 232 LAKGFDLGRKNVEFMKKKGLLDYVKHAEEILDEFYPYIRT-------PVDFAV-DYKGER 283 Query: 294 ANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKAL 353 +++ G+ +Q +D G + + + + KA+ IV NGP GVFE E+FA GT + Sbjct: 284 VEIDLLSENRGLLHQYQIMDIGKRTAEKYREILMKARIIVANGPMGVFEREEFAIGTVEV 343 Query: 354 LDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELP 407 + S A ++GGG + +KYG+T I+H+STGGGA L G+ELP Sbjct: 344 FKAIADSPAFS---VLGGGHSIASIQKYGITG-ITHISTGGGAMLSFFAGEELP 393 >2IZ1-A nrPDB Length = 474 Score = 35.0 bits (79), Expect = 0.060, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 10/106 (9%) Query: 186 FLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKV 245 + K L+ F +LE P R L + GA I+ + LLD D +I GG F + Sbjct: 53 LVFTKTLEEFVGSLEKPRRIMLMVQAGAATDATIKSLLPLLDIGDILIDGGNTHFP-DTM 111 Query: 246 LENTEIGDSIFD---------KAGAEIVPKLMEKAKAKGVEVVLPV 282 N E+ DS + + GA + P +M + + ++V P+ Sbjct: 112 RRNAELADSGINFIGTGVSGGEKGALLGPSMMPGGQKEAYDLVAPI 157 >2ZYA-A nrPDB Length = 480 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 10/100 (10%) Query: 192 LKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEI 251 +K F ++LE P R L + GA I + LDK D II GG F + N E+ Sbjct: 69 VKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQ-DTIRRNREL 127 Query: 252 GDSIFDKAGAEIV---------PKLMEKAKAKGVEVVLPV 282 F+ G + P +M + + E+V P+ Sbjct: 128 SAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPI 167 >2W8Z-A nrPDB Length = 470 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 8/96 (8%) Query: 195 FGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF--TFKKVLENTEIG 252 F ALE P + L + GA I+ + L+K D +I GG F T ++ E E+G Sbjct: 61 FVNALEKPRKILLMVKAGAPTDATIEQLKPHLEKGDIVIDGGNTYFKDTQRRNKELAELG 120 Query: 253 DSIF------DKAGAEIVPKLMEKAKAKGVEVVLPV 282 + GA P +M + + E+V P+ Sbjct: 121 IHFIGTGVSGGEEGALKGPSIMPGGQKEAHELVRPI 156 >3SEZ-A nrPDB Length = 680 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Query: 343 FEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVA---KKYGVTDKISHVSTGGGASLE 399 FE AG + D + + + +++G GD + +A YGV D++SH + G Sbjct: 455 FENVQAGLRT--DYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKT 512 Query: 400 LLE 402 L++ Sbjct: 513 LIQ 515 >5H3C-A nrPDB Length = 174 Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 6/43 (13%) Query: 84 LQSLLGKDVTFLND------CVGPEVEAAVKASAPGSVILLEN 120 L+ L GK +TF++D +GPE+ +A+K S VI +N Sbjct: 25 LKELRGKAITFIDDEIERSRSIGPELLSAIKESRIAIVIFSKN 67 >6O4N-A nrPDB Length = 432 Score = 27.7 bits (60), Expect = 9.1, Method: Compositional matrix adjust. Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 15/131 (11%) Query: 156 ADVYINDAFGTAHR---AHSSMVGFDLP-QRAAGFLLEKEL-KYFGKALEN--PTRPFLA 208 AD + DA GT ++ ++++G L +AA L++ L +Y G + + P Sbjct: 100 ADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQRPLYRYLGGSFSHVLPCPMMNL 159 Query: 209 ILGGAKVADKIQLIDNLLDKV------DSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAE 262 I GG + +Q + ++ + +++ +G + KK+L+N ++ + D+ G Sbjct: 160 INGGMHATNGLQFQEFMIRPISAPSLKEAVRMGAEVFNALKKILQNRQLATGVGDEGG-- 217 Query: 263 IVPKLMEKAKA 273 P L A+A Sbjct: 218 FAPNLASNAEA 228 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5NP8-A nrPDB 616 e-177 1QPG-A nrPDB 613 e-176 2PAA-A nrPDB 605 e-173 1HDI-A nrPDB 580 e-166 3OZ7-A nrPDB 569 e-163 1VPE-A nrPDB 541 e-154 3UWD-A nrPDB 534 e-152 1PHP-A nrPDB 528 e-150 1FW8-A nrPDB 506 e-144 16PK-A nrPDB 499 e-142 4DG5-A nrPDB 493 e-140 3Q3V-A nrPDB 490 e-139 4NG4-A nrPDB 487 e-138 3ZLB-A nrPDB 479 e-136 4EHJ-A nrPDB 477 e-135 1V6S-A nrPDB 475 e-134 1ZMR-A nrPDB 446 e-125 5BT8-A nrPDB 444 e-125 2CUN-A nrPDB 415 e-116 Sequences not found previously or not previously below threshold: 2IZ1-A nrPDB 34 0.10 2ZYA-A nrPDB 33 0.17 2W8Z-A nrPDB 32 0.43 5FAD-A nrPDB 32 0.48 4BM5-A nrPDB 32 0.53 2P4Q-A nrPDB 31 1.1 3D3Q-A nrPDB 31 1.3 5DU2-A nrPDB 30 1.7 3RTR-A nrPDB 30 1.7 1U6G-A nrPDB 30 1.7 1OMO-A nrPDB 30 1.7 1L1F-A nrPDB 30 1.9 3VN5-A nrPDB 29 3.4 2Y1H-A nrPDB 29 4.0 4TLZ-A nrPDB 29 4.1 1YA9-A nrPDB 29 4.2 5OWV-A nrPDB 29 4.5 4B3J-C nrPDB 28 6.7 4UUD-B nrPDB 28 7.2 6DLV-b nrPDB 28 7.3 6A50-A nrPDB 28 8.4 CONVERGED! >5NP8-A nrPDB Length = 420 Score = 616 bits (1588), Expect = e-177, Method: Composition-based stats. Identities = 273/416 (65%), Positives = 321/416 (77%), Gaps = 2/416 (0%) Query: 1 MSLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVL 60 MSLS+KL++ LD+K KRV +RVDFNVP+ +IT+NQRI AA+P+IK+ L++ + VVL Sbjct: 4 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 63 Query: 61 ASHLGRPNG-ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLE 119 SHLGRP+G +KYSL PVA EL+SLLGKDV FL DCVGPEVE A A GSVILLE Sbjct: 64 MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 123 Query: 120 NLRYHIEEEGSRK-VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD 178 NLR+H+EEEG K G KVKA ++ FR LS L DVY+NDAFGTAHRAHSSMVG + Sbjct: 124 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 183 Query: 179 LPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGM 238 LPQ+A GFL++KEL YF KALE+P RPFLAILGGAKVADKIQLI+N+LDKV+ +IIGGGM Sbjct: 184 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 243 Query: 239 AFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKT 298 AFTF KVL N EIG S+FD+ GA+IV LM KA+ GV++ LPVDF+ AD F +A T Sbjct: 244 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 303 Query: 299 VTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVV 358 T GIPAGW GLD GPES K +A V +AK IVWNGP GVFE+E FA GTKAL+DEVV Sbjct: 304 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 363 Query: 359 KSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSE 414 K+++ G IIGGGDTAT K+ DK+SHVSTGGGASLELLEGK LPGV LS Sbjct: 364 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSN 419 >1QPG-A nrPDB Length = 415 Score = 613 bits (1582), Expect = e-176, Method: Composition-based stats. Identities = 414/415 (99%), Positives = 415/415 (100%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA Sbjct: 1 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 60 Query: 62 SHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL 121 SHLG+PNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL Sbjct: 61 SHLGQPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL 120 Query: 122 RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQ 181 RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQ Sbjct: 121 RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQ 180 Query: 182 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 241 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT Sbjct: 181 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 240 Query: 242 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 301 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD Sbjct: 241 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 300 Query: 302 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 361 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS Sbjct: 301 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 360 Query: 362 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK Sbjct: 361 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 415 >2PAA-A nrPDB Length = 416 Score = 605 bits (1559), Expect = e-173, Method: Composition-based stats. Identities = 261/415 (62%), Positives = 318/415 (76%), Gaps = 2/415 (0%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 +LS+KL++ +DLK KRV +RVDFNVP+ +IT+NQRI AA+P+IK+ L++ + VVL Sbjct: 1 ALSAKLTLDKVDLKGKRVIMRVDFNVPMKNNQITNNQRIKAAIPSIKHCLDNGAKSVVLM 60 Query: 62 SHLGRPNG-ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLEN 120 SHLGRP+G +KYSL PVA EL+SLL KDV FL DCVGPEVE A GS+ILLEN Sbjct: 61 SHLGRPDGIPMPDKYSLEPVADELKSLLNKDVIFLKDCVGPEVEQACANPDNGSIILLEN 120 Query: 121 LRYHIEEEGSRK-VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDL 179 LR+H+EEEG K G+K+ A V+ FR LS L DVY+NDAFGTAHRAHSSMVG +L Sbjct: 121 LRFHVEEEGKGKDSSGKKISADPAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNL 180 Query: 180 PQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA 239 PQ+A+GFL++KEL YF KALE P RPFLAILGGAKV DKIQLI N+LDKV+ +IIGGGMA Sbjct: 181 PQKASGFLMKKELDYFSKALEKPERPFLAILGGAKVKDKIQLIKNMLDKVNFMIIGGGMA 240 Query: 240 FTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTV 299 +TF K L+N +IG S+FD+ GA IV ++MEKA+ GV++V PVDF+ D F +A Sbjct: 241 YTFLKELKNMQIGASLFDEEGATIVKEIMEKAEKNGVKIVFPVDFVTGDKFDENAKVGQA 300 Query: 300 TDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVK 359 T + GIP+GW GLD GPES K+ A VA+AK IVWNGP GVFE++ FA GTKAL+DEVVK Sbjct: 301 TIESGIPSGWMGLDCGPESIKINAQIVAQAKLIVWNGPIGVFEWDAFAKGTKALMDEVVK 360 Query: 360 SSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSE 414 +++ G IIGGGDTAT K+G DK+SHVSTGGGASLELLEGK LPGV LS Sbjct: 361 ATSNGCVTIIGGGDTATCCAKWGTEDKVSHVSTGGGASLELLEGKILPGVEALSN 415 >1HDI-A nrPDB Length = 413 Score = 580 bits (1495), Expect = e-166, Method: Composition-based stats. Identities = 254/412 (61%), Positives = 304/412 (73%), Gaps = 2/412 (0%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +KL++ L++K KRV +RVDFNVP+ +IT+N RI AA+P+IK+ L+ + VVL SHL Sbjct: 1 NKLTLDKLNVKGKRVVMRVDFNVPMAAAQITNNARIKAAVPSIKFCLDDGAKSVVLMSHL 60 Query: 65 GRPNG-ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRY 123 GRP+G +KYSL PVA EL+S LGK V FL DCVGP VE A A GSVILLENLR+ Sbjct: 61 GRPDGSPMPDKYSLQPVAAELKSALGKAVLFLKDCVGPAVEKACADPAAGSVILLENLRF 120 Query: 124 HIEEEGSRK-VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQR 182 H+EEEG K G K ++ FR LS+L DVY+NDAFGTAHRAHSSMVG +LP++ Sbjct: 121 HVEEEGKGKDASGNKAAGEPAKIKAFRASLSALGDVYVNDAFGTAHRAHSSMVGVNLPKK 180 Query: 183 AAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTF 242 A FL++KEL YF A E+P RPFLAILGGAKVADKIQLI+N+LDKV+ +IIGGGMAFTF Sbjct: 181 AGAFLMKKELNYFAAAAESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTF 240 Query: 243 KKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDK 302 KVL N EIG S+FD+AG +IV LM KA A GV++ LPVDF+ AD F A T Sbjct: 241 LKVLNNMEIGTSLFDEAGKKIVKNLMSKAAANGVKITLPVDFVTADKFDEQAKIGQATVA 300 Query: 303 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362 GIPAGW GLD GP+S ++ VA+AK IVWNGP GVFE+E FA GTKAL+DEVVK+++ Sbjct: 301 SGIPAGWMGLDCGPKSSAKYSEAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATS 360 Query: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSE 414 G IIGGGDTAT K+ D +SHVSTGGGASLELLEGK LPGV LS Sbjct: 361 RGCITIIGGGDTATCCAKWNTEDNVSHVSTGGGASLELLEGKVLPGVDALSN 412 >3OZ7-A nrPDB Length = 417 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 252/414 (60%), Positives = 319/414 (77%), Gaps = 2/414 (0%) Query: 3 LSSKLSVQDL-DLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 L +KLS+ DL D+K+K+V +RVDFNVP++ I RI A LPTI ++ + ++L Sbjct: 4 LGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILI 63 Query: 62 SHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENL 121 SH GRP+G RNEKY+L PVA+ L+ LLG++V FLNDCVG EVE + A+ SVILLENL Sbjct: 64 SHCGRPDGLRNEKYTLKPVAETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENL 123 Query: 122 RYHIEEEGSR-KVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLP 180 R+HIEEEG +G KVKA+KEDV+KF+++L+ LADV+INDAFGTAHRAHSSMVG L Sbjct: 124 RFHIEEEGKGVDANGNKVKANKEDVEKFQNDLTKLADVFINDAFGTAHRAHSSMVGVKLN 183 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 +A+GFL++KEL+YF KALENP RP LAILGGAKV+DKIQLI NLLDKVD +IIGGGMA+ Sbjct: 184 VKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMAY 243 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVT 300 TFKKVL N +IG S+FD+AG++IV ++MEKAKAK V++ LPVDF IAD F +ANTK VT Sbjct: 244 TFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFVT 303 Query: 301 DKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKS 360 D+EGIP W GLD GP+S + + + +KT++WNGP GVFE FA G+ L+ VV+ Sbjct: 304 DEEGIPDNWMGLDAGPKSIENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEV 363 Query: 361 SAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSE 414 + G I+GGGDTA++ ++ ++ISHVSTGGGASLELLEGKELPGV LS Sbjct: 364 TKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLELLEGKELPGVLALSN 417 >1VPE-A nrPDB Length = 398 Score = 541 bits (1393), Expect = e-154, Method: Composition-based stats. Identities = 204/412 (49%), Positives = 269/412 (65%), Gaps = 17/412 (4%) Query: 6 KLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLG 65 K++++D+DLK KRV +RVDFNVP+ + + RI AALPTIKY LE + V+L SHLG Sbjct: 2 KMTIRDVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAK-VILLSHLG 60 Query: 66 RPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHI 125 RP GE + ++SLAPVAK L LLGK+V F+ VG EV+ AV+ G V+LLEN R+H Sbjct: 61 RPKGEPSPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHP 120 Query: 126 EEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD-LPQRAA 184 E + + +SLAD+++NDAFGTAHRAH+S VG A Sbjct: 121 GETKNDP--------------ELAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVA 166 Query: 185 GFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKK 244 GFL+EKE+K+ K NP +P++ +LGGAKV+DKI +I NL++K D I+IGG M FTF K Sbjct: 167 GFLMEKEIKFLSKVTYNPEKPYVVVLGGAKVSDKIGVITNLMEKADRILIGGAMMFTFLK 226 Query: 245 VLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEG 304 L E+G S ++ ++ +L+EKAK KGVE+VLPVD +IA K V +G Sbjct: 227 AL-GKEVGSSRVEEDKIDLAKELVEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDDG 285 Query: 305 IPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAG 364 IP GW GLD GPE+ +LF ++ AKT+VWNGP GVFE + FA GTK + + + G Sbjct: 286 IPEGWMGLDIGPETIELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKG 345 Query: 365 NTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 ++GGGD+A K+G+ DK SHVSTGGGASLE LEGKELPG+A + KK Sbjct: 346 AITVVGGGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELPGIASMRIKK 397 >3UWD-A nrPDB Length = 394 Score = 534 bits (1377), Expect = e-152, Method: Composition-based stats. Identities = 203/412 (49%), Positives = 272/412 (66%), Gaps = 20/412 (4%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +K S++D+DLK KRVF RVDFNVP+ KIT RI AALPTI+Y++E + V+LASHL Sbjct: 2 NKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAK-VILASHL 60 Query: 65 GRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYH 124 GRP G+ E+ L PVA L LLGKDV ++ GP + V A G V++LEN+R++ Sbjct: 61 GRPKGQAVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFY 120 Query: 125 IEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRA 183 EE + + E ++LAD+++NDAFG AHRAH+S G D Sbjct: 121 AGEEKN--------------DAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAV 166 Query: 184 AGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFK 243 +G L+EKEL+ GKAL NP RPF AI+GGAKV DKI LI +LLDKVD++IIGGG+A+TF Sbjct: 167 SGLLMEKELEVLGKALSNPERPFAAIIGGAKVKDKIGLIRHLLDKVDNLIIGGGLAYTFV 226 Query: 244 KVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKE 303 K L EIG S+ + E+ + M+ AK KGV +PVD +I + FS A TK V + Sbjct: 227 KAL-GHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIV-GID 284 Query: 304 GIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAA 363 IP+ W+G+D GP++R+++A + +K +VWNGP GVFE FA GTKA+ + A Sbjct: 285 SIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALAD--AE 342 Query: 364 GNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 G +IGGGD+A +K+G+ DK+SH+STGGGASLE +EGKELPGV L++K Sbjct: 343 GTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK 394 >1PHP-A nrPDB Length = 394 Score = 528 bits (1361), Expect = e-150, Method: Composition-based stats. Identities = 203/412 (49%), Positives = 273/412 (66%), Gaps = 20/412 (4%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +K +++D+D++ KRVF RVDFNVP++ IT + RI AALPTI+Y++EH + V+LASHL Sbjct: 2 NKKTIRDVDVRGKRVFCRVDFNVPMEQGAITDDTRIRAALPTIRYLIEHGAK-VILASHL 60 Query: 65 GRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYH 124 GRP G+ E+ L VAK L LL + V N+ VG EV+AAV G V+LLEN+R++ Sbjct: 61 GRPKGKVVEELRLDAVAKRLGELLERPVAKTNEAVGDEVKAAVDRLNEGDVLLLENVRFY 120 Query: 125 IEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD-LPQRA 183 EE + + + LAD+Y+NDAFG AHRAH+S G Sbjct: 121 PGEEKNDP--------------ELAKAFAELADLYVNDAFGAAHRAHASTEGIAHYLPAV 166 Query: 184 AGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFK 243 AGFL+EKEL+ GKAL NP RPF AI+GGAKV DKI +IDNLL+KVD++IIGGG+A+TF Sbjct: 167 AGFLMEKELEVLGKALSNPDRPFTAIIGGAKVKDKIGVIDNLLEKVDNLIIGGGLAYTFV 226 Query: 244 KVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKE 303 K L ++G S+ ++ E+ MEKAK KGV +PVD ++AD F+ DANTK V + Sbjct: 227 KAL-GHDVGKSLLEEDKIELAKSFMEKAKEKGVRFYMPVDVVVADRFANDANTKVV-PID 284 Query: 304 GIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAA 363 IPA W LD GP++R+L+ + ++K +VWNGP GVFE + FA GTKA + A Sbjct: 285 AIPADWSALDIGPKTRELYRDVIRESKLVVWNGPMGVFEMDAFAHGTKA--IAEALAEAL 342 Query: 364 GNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 +IGGGD+A +K+G+ DK+ H+STGGGASLE +EGK+LPGV L +K Sbjct: 343 DTYSVIGGGDSAAAVEKFGLADKMDHISTGGGASLEFMEGKQLPGVVALEDK 394 >1FW8-A nrPDB Length = 416 Score = 506 bits (1302), Expect = e-144, Method: Composition-based stats. Identities = 343/344 (99%), Positives = 343/344 (99%) Query: 73 EKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRK 132 KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRK Sbjct: 2 SKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRK 61 Query: 133 VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKEL 192 VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKEL Sbjct: 62 VDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKEL 121 Query: 193 KYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIG 252 KYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIG Sbjct: 122 KYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIG 181 Query: 253 DSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGL 312 DSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGL Sbjct: 182 DSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGL 241 Query: 313 DNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGG 372 DNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGG Sbjct: 242 DNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGG 301 Query: 373 DTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 DTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK Sbjct: 302 DTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 345 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 71/71 (100%), Positives = 71/71 (100%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 61 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA Sbjct: 346 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLA 405 Query: 62 SHLGRPNGERN 72 SHLGRPNGERN Sbjct: 406 SHLGRPNGERN 416 >16PK-A nrPDB Length = 415 Score = 499 bits (1286), Expect = e-142, Method: Composition-based stats. Identities = 190/429 (44%), Positives = 264/429 (61%), Gaps = 34/429 (7%) Query: 6 KLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLG 65 K S+ + DLK K+V IRVDFNVP+ KIT++ RI +ALPT+K VL VL SHLG Sbjct: 2 KKSINECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGS-CVLMSHLG 60 Query: 66 RPNG----------------ERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKA 109 RP G +K +L PVAK L LL + VTF DC+ V Sbjct: 61 RPKGIPMAQAGKIRSTGGVPGFQQKATLKPVAKRLSELLLRPVTFAPDCL--NAADVVSK 118 Query: 110 SAPGSVILLENLRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHR 169 +PG V+LLEN+R++ +EEGS+K +D + L+S DVYI+DAFGTAHR Sbjct: 119 MSPGDVVLLENVRFY-KEEGSKKA---------KDREAMAKILASYGDVYISDAFGTAHR 168 Query: 170 AHSSMVGFD--LPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLD 227 ++M G L AAG+L+EKE+ YF K L NP RP +AI+GGAKV+DKIQL+DN+L Sbjct: 169 DSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQ 228 Query: 228 KVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIA 287 ++D ++IGG MA+TF K + IG S +++ E L++KA+ + V+V+LP+D + Sbjct: 229 RIDYLLIGGAMAYTFLKA-QGYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCH 287 Query: 288 DAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFA 347 F A ++ +T+ + IP G LD GP++ + + T+ K K+ +WNGP GVFE ++ Sbjct: 288 TEFKA-VDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYS 346 Query: 348 AGTKALLDEVVKSS-AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKEL 406 GT A+ + + + G IIGGGD+A+ A+ G ++SHVSTGGGASLELLEGK L Sbjct: 347 KGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTL 406 Query: 407 PGVAFLSEK 415 PGV L +K Sbjct: 407 PGVTVLDDK 415 >4DG5-A nrPDB Length = 403 Score = 493 bits (1270), Expect = e-140, Method: Composition-based stats. Identities = 191/414 (46%), Positives = 263/414 (63%), Gaps = 20/414 (4%) Query: 4 SSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASH 63 S+K V DLDLK K V +R DFNVPL +IT++ RIV ALPTI+Y++E + +VL SH Sbjct: 8 SAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGK-IVLFSH 66 Query: 64 LGRPNGERNE-KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLR 122 LG+ E ++ K +L PVA++L L K+V F+ + G ++EAA+K G V+L+EN R Sbjct: 67 LGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTR 126 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLP-Q 181 Y +DG+K + ++ K+ +SL DV++NDAFGTAHR H+S VG + Sbjct: 127 Y-------EDLDGKKESKNDPELGKY---WASLGDVFVNDAFGTAHREHASNVGISTHLE 176 Query: 182 RAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 241 AAGFL++KE+K+ G + +P +P +AILGGAKV+DKI +I NL++ D IIIGGGMA+T Sbjct: 177 TAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYT 236 Query: 242 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 301 F K + EIG S+ ++ + L+EK G ++VLPVD +A FS DA TV Sbjct: 237 FLKA-QGKEIGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKI-TVVP 291 Query: 302 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 361 + IPA +G+D GP + KLFA + A T+VWNGP GVFEF FA GT + + Sbjct: 292 SDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANL- 350 Query: 362 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 IIGGGD+A A G + +H+STGGGASLE LEGKELPG+ ++ K Sbjct: 351 -KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK 403 >3Q3V-A nrPDB Length = 403 Score = 490 bits (1262), Expect = e-139, Method: Composition-based stats. Identities = 193/420 (45%), Positives = 267/420 (63%), Gaps = 26/420 (6%) Query: 2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDG-KKITSNQRIVAALPTIKYVLEHHPRYVVL 60 ++S +S++D+DL K+VFIR DFNVP D IT ++RI +A+PTI+Y L++ V+L Sbjct: 3 AMSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCS-VIL 61 Query: 61 ASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLEN 120 ASHLGRP E + KYSL PVAK L LL K++ D +G + + G ++LLEN Sbjct: 62 ASHLGRPK-EISSKYSLEPVAKRLARLLDKEIVMAKDVIGEDAKTKAMNLKAGEILLLEN 120 Query: 121 LRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVG---- 176 LR+ E+G K D + EL+S+ VYINDAFG HRAHSS+ Sbjct: 121 LRF---EKGETKND-----------ENLAKELASMVQVYINDAFGVCHRAHSSVEAITKF 166 Query: 177 FDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGG 236 FD + AGFLL+KE+ + +++P RPF+A++GG+KV+ K+Q + NLL KVD +IIGG Sbjct: 167 FDEKHKGAGFLLQKEIDFASNLIKHPARPFVAVVGGSKVSGKLQALTNLLPKVDKLIIGG 226 Query: 237 GMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANT 296 GMAFTF K L +IG+S+ ++ E K++ K K GV++ LPVD + A A S D Sbjct: 227 GMAFTFLKAL-GYDIGNSLLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPACSQDVPM 285 Query: 297 KTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDE 356 K V +E IP GW GLD GP S +LF ++ A+TI WNGP GVFE +KF+ G+ + Sbjct: 286 KFVPAQE-IPNGWMGLDIGPASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHY 344 Query: 357 VVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK 416 + + A T ++GGGDTA V + G D+++ +STGGGASLEL+EGKELPGV L K+ Sbjct: 345 ISEGHA---TSVVGGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKE 401 >4NG4-A nrPDB Length = 404 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 175/414 (42%), Positives = 249/414 (60%), Gaps = 31/414 (7%) Query: 6 KLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLG 65 LS+ +L+L +KRV IR D NVP+ KIT+++RIV ALPTI+ +E R ++L SHLG Sbjct: 14 FLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMIL-SHLG 72 Query: 66 RPN-GERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLRY 123 RP G+ +++SLAPVA+ L L + V +ND + G VE PG IL EN+R+ Sbjct: 73 RPEEGKFEKEFSLAPVARLLSKKLNQKVPLINDWLKGVAVE-------PGQAILCENVRF 125 Query: 124 HIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQR- 182 + K E+ + ++ L D+++ DAF TAHRA +S G + Sbjct: 126 N--------------KGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKL 171 Query: 183 -AAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFT 241 AG LL E++ +ALENP +P +A++GG+KV+ KI L++NLLDKVD +I+GGG+A T Sbjct: 172 ACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANT 231 Query: 242 FKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTD 301 F K + IG S+ + + + EKA K V + LPVD I+AD S DA TV + Sbjct: 232 FLKA-QGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKA-TVKN 289 Query: 302 KEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSS 361 + + + D GP + +A +A+A TIVWNGP GVFE E F+ GT+AL V KS+ Sbjct: 290 IDAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKST 349 Query: 362 AAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 A I+GGGDT K+ +TD++S+VST GGA LE LEGK LP + L+++ Sbjct: 350 A---YSIVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGKILPAIKILTQR 400 >3ZLB-A nrPDB Length = 398 Score = 479 bits (1234), Expect = e-136, Method: Composition-based stats. Identities = 201/415 (48%), Positives = 273/415 (65%), Gaps = 22/415 (5%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 +KL+V+D+DLK K+V +RVDFNVPL IT++ RI AALPTIKY++E R +L SHL Sbjct: 2 AKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRA-ILFSHL 60 Query: 65 GRPNGERNEK-YSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRY 123 GR E ++ SLAPVA +L + LG+DV F G E+EAA+ A G V+L+EN RY Sbjct: 61 GRVKEESDKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEAAINALEDGQVLLVENTRY 120 Query: 124 HIEEEGSRKVDGQKVKASKEDVQKFRHELSSLAD-VYINDAFGTAHRAHSSMVGF--DLP 180 VDG+K + ++ K+ +SL D +++NDAFGTAHRAH+S VG ++ Sbjct: 121 -------EDVDGKKESKNDPELGKY---WASLGDGIFVNDAFGTAHRAHASNVGISANVE 170 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 + AGFLLE E+ Y +A+E P RPF+AILGG+KV+DKI +I+NLL+K D ++IGGGM + Sbjct: 171 KAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTY 230 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVT 300 TF K + EIG+S+ ++ ++ L+EKA K ++LPVD A+AF+ + T Sbjct: 231 TFYKA-QGIEIGNSLVEEDKLDVAKALLEKANGK---LILPVDSKEANAFAGYTEVRD-T 285 Query: 301 DKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKS 360 + E + G+ GLD GP+S F + AKT+VWNGP GVFE F AGT ++D +VK Sbjct: 286 EGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQ 345 Query: 361 SAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 G IIGGGD+A A G DK S +STGGGAS+ELLEGK LPG+A L+EK Sbjct: 346 P--GVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK 398 >4EHJ-A nrPDB Length = 392 Score = 477 bits (1229), Expect = e-135, Method: Composition-based stats. Identities = 175/415 (42%), Positives = 259/415 (62%), Gaps = 31/415 (7%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 S L+++D+DLKDK+V +RVDFNVP+ K+TS RI AA+PTI+Y+L+ V+L SHL Sbjct: 2 SFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGA-VILMSHL 60 Query: 65 GRP-NGERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLR 122 GRP GE + ++SL PVAK L ++ K V F D + G +V+A G +++ EN+R Sbjct: 61 GRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKA-------GEIVMCENVR 113 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD--LP 180 ++ E+ S +++SL DV++ DAF TAHRA +S G +P Sbjct: 114 FNSGEKKSTD--------------DLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIP 159 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 AG LL E++ KAL++P +P AI+GG+KV+ K+ +++NLLDKV+ +I+GGG+A Sbjct: 160 VACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIAN 219 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVT 300 TF K E ++G+S++++ +++ KAKA GV + +PVD +A FS +A + Sbjct: 220 TFIKA-EGFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQA-IIK 277 Query: 301 DKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKS 360 + A LD GPES+K+ A + A TI+WNGP GVFEF+ FA GTKAL + +S Sbjct: 278 KVSDVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQS 337 Query: 361 SAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 A + GGGDT +K+G+ D++S++ST GGA LE LEGK+LP + L EK Sbjct: 338 HAF---SVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEK 389 >1V6S-A nrPDB Length = 390 Score = 475 bits (1223), Expect = e-134, Method: Composition-based stats. Identities = 163/408 (39%), Positives = 239/408 (58%), Gaps = 23/408 (5%) Query: 8 SVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRP 67 ++ DLD K KRV +RVD+NVP+ K+ RI+ +LPT++++L V+L SHLGRP Sbjct: 3 TLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLAGGASLVLL-SHLGRP 61 Query: 68 NGERNEKYSLAPVAKELQSLLGKDVTFLNDCVG-PEVEAAVKASAPGSVILLENLRYHIE 126 G + KYSLAPV + L++ L + F G E +A PG V+LLEN+R+ Sbjct: 62 KGP-DPKYSLAPVGEALRAHL-PEARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPG 119 Query: 127 EEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAG 185 EE + + + L + ++ DAFG+AHRAH+S+VG L AG Sbjct: 120 EEKNDP--------------ELSARYARLGEAFVLDAFGSAHRAHASVVGVARLLPAYAG 165 Query: 186 FLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKV 245 FL+EKE++ + L++P RP+ +LGGAKV+DKI +I++LL ++D ++IGG MAFTF K Sbjct: 166 FLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFTFLKA 225 Query: 246 LENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGI 305 L E+G S+ ++ ++ L+ +A+A GV V LP D + A+ A T+ V I Sbjct: 226 LGG-EVGRSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVETR-VFPARAI 283 Query: 306 PAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGN 365 P + GLD GP++R+ FA + A+T+ WNGP GVFE F GT A+ + G Sbjct: 284 PVPYMGLDIGPKTREAFARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAIAALE--GA 341 Query: 366 TVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLS 413 ++GGGD+ + G+ ++ HVSTGGGASLE LE LPG+ L Sbjct: 342 FTVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFLEKGTLPGLEVLE 389 >1ZMR-A nrPDB Length = 387 Score = 446 bits (1147), Expect = e-125, Method: Composition-based stats. Identities = 163/415 (39%), Positives = 233/415 (56%), Gaps = 36/415 (8%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 S + + DLDL KRVFIR D NVP+ K+TS+ RI A+LPTI+ L+ + V++ SHL Sbjct: 2 SVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAK-VMVTSHL 60 Query: 65 GRP-NGERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLR 122 GRP GE NE++SL PV L+ L V + D + G +V A G +++LEN+R Sbjct: 61 GRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDV-------AEGELVVLENVR 113 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF--DLP 180 ++ K K+D + + ++L DV++ DAFGTAHRA +S G Sbjct: 114 FN--------------KGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFAD 159 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 AG LL EL GKAL+ P RP +AI+GG+KV+ K+ ++D+L D +I+GGG+A Sbjct: 160 VACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIAN 219 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVT 300 TF + ++G S+++ + +L+ + +P D +A FS A T+ Sbjct: 220 TFIAA-QGHDVGKSLYEADLVDEAKRLLTTCN-----IPVPSDVRVATEFSETAPA-TLK 272 Query: 301 DKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKS 360 + A Q LD G S + A + AKTI+WNGP GVFEF F GT+ + + + S Sbjct: 273 SVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADS 332 Query: 361 SAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEK 415 A I GGGDT +G+ DKIS++STGGGA LE +EGK LP VA L E+ Sbjct: 333 EAF---SIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEER 384 >5BT8-A nrPDB Length = 403 Score = 444 bits (1142), Expect = e-125, Method: Composition-based stats. Identities = 172/424 (40%), Positives = 235/424 (55%), Gaps = 44/424 (10%) Query: 5 SKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHL 64 + + DL+L KRV IR D NVP+ ITS+ R+ AALPTIK LE V++ SHL Sbjct: 10 NFQRMTDLNLAGKRVLIREDLNVPVKNGVITSDARLRAALPTIKAALEKGAA-VMVFSHL 68 Query: 65 GRP-NGERNEKYSLAPVAKELQSLLGKDVTFLNDCV-GPEVEAAVKASAPGSVILLENLR 122 GRP GE + SLAPVA L LG++V D + G EVEA G V+LLEN+R Sbjct: 69 GRPVEGEPKPEQSLAPVAAYLTEALGQEVKLFTDYLDGVEVEA-------GQVVLLENVR 121 Query: 123 YHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFD--LP 180 ++ E K++ + + ++L DV++ DAFGTAHRA +S G P Sbjct: 122 FNPGE--------------KKNNPELAQKYAALCDVFVMDAFGTAHRAEASTEGVARFAP 167 Query: 181 QRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAF 240 AAG LL EL G+A++ P +P +AI+ G+KV+ K+ ++++L D +I+GGG+A Sbjct: 168 VAAAGPLLAAELDALGRAMQTPEKPMVAIVAGSKVSTKLDVLNSLSGICDQLIVGGGIAN 227 Query: 241 TFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAF---------S 291 TF +G S+++ E ++ K V V LP D ++ADA S Sbjct: 228 TFLAA-AGYNVGKSLYEADLVETAKQIAAK-----VSVPLPTDVVVADASQINFEDFLGS 281 Query: 292 ADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTK 351 A + E + A LD GPE+ K FA + +KTI+WNGP GVFE ++F GTK Sbjct: 282 LAAAQAVIKKVEDVTANDMILDVGPETAKAFANILTTSKTILWNGPVGVFEVDQFGEGTK 341 Query: 352 ALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAF 411 AL V +S A I GGGDT KY V D+I ++STGGGA LE +EGK LP VA Sbjct: 342 ALSLAVAQSDAF---SIAGGGDTLAAIDKYNVADQIGYISTGGGAFLEFVEGKTLPAVAV 398 Query: 412 LSEK 415 L E+ Sbjct: 399 LLER 402 >2CUN-A nrPDB Length = 410 Score = 415 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 138/420 (32%), Positives = 220/420 (52%), Gaps = 35/420 (8%) Query: 7 LSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGR 66 ++D + +K VF+RVD N P+ KI S+ R A LPTI+Y++E + VV+ +H G+ Sbjct: 2 FRLEDFNFHNKTVFLRVDLNSPMKDGKIISDARFKAVLPTIRYLIESGAK-VVIGTHQGK 60 Query: 67 PNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIE 126 P E + + A+ L LL + V ++ D G +K G V +LENLR+ E Sbjct: 61 PYSE--DYTTTEEHARVLSELLDQHVEYIEDIFGRYAREKIKELKSGEVAILENLRFSAE 118 Query: 127 EEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAG 185 E ++ ++ + K + K +LS + D +NDAF TAHR+ S+VGF + G Sbjct: 119 EVKNKPIE----ECEKTFLVK---KLSKVIDYVVNDAFATAHRSQPSLVGFARIKPMIMG 171 Query: 186 FLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLL--DKVDSIIIGGGMA--FT 241 FL+EKE++ +A + P + +LGGAKV D +++++N+L ++ D ++ GG +A FT Sbjct: 172 FLMEKEIEALMRAYYSKDSPKIYVLGGAKVEDSLKVVENVLRRERADLVLTGGLVANVFT 231 Query: 242 FKKVLE----NTEI----GDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSAD 293 K + N E G + K EI+ + + PVDF + D Sbjct: 232 LAKGFDLGRKNVEFMKKKGLLDYVKHAEEILDEFYPYIRT-------PVDFAV-DYKGER 283 Query: 294 ANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKAL 353 +++ G+ +Q +D G + + + + KA+ IV NGP GVFE E+FA GT + Sbjct: 284 VEIDLLSENRGLLHQYQIMDIGKRTAEKYREILMKARIIVANGPMGVFEREEFAIGTVEV 343 Query: 354 LDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLS 413 + S A ++GGG + +KYG+T I+H+STGGGA L G+ELP + L Sbjct: 344 FKAIADSPAF---SVLGGGHSIASIQKYGITG-ITHISTGGGAMLSFFAGEELPVLRALQ 399 >2IZ1-A nrPDB Length = 474 Score = 34.2 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 29/72 (40%) Query: 169 RAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDK 228 R S + + K L+ F +LE P R L + GA I+ + LLD Sbjct: 36 RTTSKTEEVFKEHQDKNLVFTKTLEEFVGSLEKPRRIMLMVQAGAATDATIKSLLPLLDI 95 Query: 229 VDSIIIGGGMAF 240 D +I GG F Sbjct: 96 GDILIDGGNTHF 107 >2ZYA-A nrPDB Length = 480 Score = 33.4 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 16/108 (14%) Query: 192 LKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKK------- 244 +K F ++LE P R L + GA I + LDK D II GG TF + Sbjct: 69 VKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGG---NTFFQDTIRRNR 125 Query: 245 --VLENTEI---GDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIA 287 E G S ++ + P +M + + E+V P+ IA Sbjct: 126 ELSAEGFNFIGTGVSGGEEGALK-GPSIMPGGQKEAYELVAPILTKIA 172 >2W8Z-A nrPDB Length = 470 Score = 32.3 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 16/125 (12%) Query: 192 LKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLE--NT 249 ++ F ALE P + L + GA I+ + L+K D +I GG T+ K + N Sbjct: 58 IEEFVNALEKPRKILLMVKAGAPTDATIEQLKPHLEKGDIVIDGG---NTYFKDTQRRNK 114 Query: 250 EI----------GDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTV 299 E+ G S ++ + P +M + + E+V P+ IA + T + Sbjct: 115 ELAELGIHFIGTGVSGGEEGALK-GPSIMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYI 173 Query: 300 TDKEG 304 Sbjct: 174 GPDGA 178 >5FAD-A nrPDB Length = 161 Score = 31.9 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 6/116 (5%) Query: 9 VQDLDLKDKRVFIRV--DFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLAS--HL 64 V DL D R+ I DFNV +++RI AL I+ +V + + Sbjct: 32 VYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTGRASIVKGNFFEV 91 Query: 65 GRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLEN 120 + L V + L+ L K++ V E E ++ P VI +E+ Sbjct: 92 DISEATVVTMFLLTNVNEMLKPKLEKELKPGTRVVSHEFE--IRGWNPKEVIKVED 145 >4BM5-A nrPDB Length = 348 Score = 31.9 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Query: 17 KRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHH 54 +RV +D + P+ K+T ++R+ A I++ +E+ Sbjct: 189 RRVCRELDVD-PVRDLKLTEDRRVRAFRAEIEHAIENG 225 >2P4Q-A nrPDB Length = 497 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 17/45 (37%), Positives = 23/45 (51%) Query: 192 LKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGG 236 ++ F L+ P + L + GA V I I LL+K D II GG Sbjct: 65 IEDFISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGG 109 >3D3Q-A nrPDB Length = 340 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 43/106 (40%), Gaps = 13/106 (12%) Query: 203 TRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAE 262 T+PFL ++ G + K +L + K + II G +V + +IG + E Sbjct: 5 TKPFLIVIVGPTASGKTELSIEVAKKFNGEIISGDS----MQVYQGMDIGTAKVTTEEME 60 Query: 263 IVPKLMEKAKAKGVEVVLPVDFIIADAFSADAN--TKTVTDKEGIP 306 +P M ++++ P A F A K +T + +P Sbjct: 61 GIPHYM-------IDILPPDASFSAYEFKKRAEKYIKDITRRGKVP 99 >5DU2-A nrPDB Length = 419 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 32/81 (39%), Gaps = 2/81 (2%) Query: 42 AALPTIKYVLEHHPRYVVLAS-HLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVG 100 A L + ++ H V+ + GRP + + P+A+ + L V + G Sbjct: 312 AVLEHARLLVTHGGIGAVMDALTAGRPMVVVPFTFDVKPMARRVGELGLGTVVPAAEFTG 371 Query: 101 PEVEAAVKASAPGSVILLENL 121 + AV+ A G LE + Sbjct: 372 ARLREAVEDLA-GDRAALERV 391 >3RTR-A nrPDB Length = 368 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 36/103 (34%), Gaps = 7/103 (6%) Query: 12 LDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGER 71 L K+K+ +RV+ NVP+ ++ + + + +L ++ + Sbjct: 265 LGYKNKK--LRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIM-----KMRKVL 317 Query: 72 NEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGS 114 + L V +L S V + C+ +E G Sbjct: 318 KHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGE 360 >1U6G-A nrPDB Length = 776 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 36/103 (34%), Gaps = 7/103 (6%) Query: 12 LDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGER 71 L K+K+ +RV+ NVP+ ++ + + + +L ++ + Sbjct: 673 LGYKNKK--LRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIM-----KMRKVL 725 Query: 72 NEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGS 114 + L V +L S V + C+ +E G Sbjct: 726 KHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGE 768 >1OMO-A nrPDB Length = 322 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 39/106 (36%), Gaps = 9/106 (8%) Query: 236 GGMAFTFKKVLEN-TEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVL-PV------DFIIA 287 G A+ + L +IG+ + K + + +G+ + P D ++ Sbjct: 134 GTQAYFQLEALRRVFDIGEVKAYDVREKAAKKFVSYCEDRGISASVQPAEEASRCDVLVT 193 Query: 288 DAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIV 333 S K +EG G D GP ++L + KAK +V Sbjct: 194 TTPSRKPVVKAEWVEEGTHINAIGAD-GPGKQELDVEILKKAKIVV 238 >1L1F-A nrPDB Length = 505 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 33/152 (21%), Positives = 49/152 (32%), Gaps = 23/152 (15%) Query: 171 HSSMVGFDLPQRAAGFLLEKELKYFGKALE-------NPTRPFLAILG-GAK-----VAD 217 H S++GF + G +LE + A N R I+ GA AD Sbjct: 302 HGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEAD 361 Query: 218 KIQLIDNLLDKVDSIIIGGGMA---FTFKKVLENTEIGDSIFDKAG-------AEIVPKL 267 KI L N++ D + GG+ F + K L + G F + L Sbjct: 362 KIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESL 421 Query: 268 MEKAKAKGVEVVLPVDFIIADAFSADANTKTV 299 K G + + D S + V Sbjct: 422 ERKFGKHGGTIPIVPTAEFQDRISGASEKDIV 453 >3VN5-A nrPDB Length = 257 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 61/164 (37%), Gaps = 36/164 (21%) Query: 67 PNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSV----------- 115 P + SL P ++ + L K V L + P V+A P Sbjct: 96 PEENYLKVSSLNP--RDTKRLSDKRVERLYLALKPLVKAYCYEIKPEEYNKLYRKFRNLN 153 Query: 116 --------ILLENLRYHIEEEGSRKVDGQKVKASKE-------DVQKFRHELSSLADVYI 160 +L+E ++ EE G +V K + S + + R+ ++A ++ Sbjct: 154 KMMTHFYKLLIERVK---EECGVSEVVVDKYQPSNPFGEDVIFETEAERNLAVAVASIFA 210 Query: 161 NDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTR 204 F + + +G +P+ + KE+K K+L+NP R Sbjct: 211 RYKFLQSLKEVERELGIKIPKGTS-----KEVKELAKSLKNPER 249 >2Y1H-A nrPDB Length = 272 Score = 28.8 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 13/26 (50%) Query: 42 AALPTIKYVLEHHPRYVVLASHLGRP 67 A PTI + E V+L + GRP Sbjct: 149 AGRPTINLLQEQGAEKVLLHAFDGRP 174 >4TLZ-A nrPDB Length = 443 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 42/114 (36%), Gaps = 8/114 (7%) Query: 283 DFIIADAFSADANTKTVTDKEGIPAGWQGLDNG-PE-SRKLFAATVAKAKTIVWNGPPGV 340 + +A S D+ + G P +D PE +R + A + + +V P GV Sbjct: 134 ESKLAHEVSYDSEVTAIRPGPGRPVDSVLVDVSTPEATRTVEARNIVISTGLVPRMPAGV 193 Query: 341 FEFEKFAAGTKALLDEVVKSSAAGN--TVIIGGGDTATVAKKY---GVTDKISH 389 + ++F + LD + GGG +A ++ D + H Sbjct: 194 -QSDEFVWHSSRFLDHFRDRDPRSLRRVAVAGGGQSAAEIVRFLHDNRPDTVVH 246 >1YA9-A nrPDB Length = 181 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 19/37 (51%) Query: 74 KYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKAS 110 + L PVA+E ++ LGK+V +G ++E Sbjct: 70 EEQLGPVAEETRARLGKEVQAAQARLGADMEDLRNRL 106 >5OWV-A nrPDB Length = 732 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 19/32 (59%) Query: 219 IQLIDNLLDKVDSIIIGGGMAFTFKKVLENTE 250 + L +NL++K+D + + MA F K L + E Sbjct: 384 VDLDENLVEKIDFLCVSAKMASDFYKGLASKE 415 >4B3J-C nrPDB Length = 403 Score = 28.0 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Query: 361 SAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGAS 397 A +GG D +KY +KI+HV TGG +S Sbjct: 223 PAFEGLAALGGFDDVA-LQKYHWVEKINHVHTGGNSS 258 >4UUD-B nrPDB Length = 864 Score = 28.0 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 58/164 (35%), Gaps = 19/164 (11%) Query: 186 FLLEKELKYFGKALENPTR--PFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGM----- 238 L+ + F +N P +A++GG + A K +++N + + D + G G+ Sbjct: 11 PLVNRLQDAFSAIGQNADLDLPQIAVVGG-QSAGKSSVLENFVGR-DFLPRGSGIVTRRP 68 Query: 239 -------AFTFKKVLENTEIGD--SIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADA 289 A T + + G + F++ EI + +P++ + Sbjct: 69 LVLQLVNATTEYAEFLHCK-GKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSP 127 Query: 290 FSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIV 333 + + +P G Q D + R + V K ++ Sbjct: 128 HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLI 171 >6DLV-b nrPDB Length = 748 Score = 28.0 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 58/164 (35%), Gaps = 19/164 (11%) Query: 186 FLLEKELKYFGKALENPTR--PFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGM----- 238 L+ + F +N P +A++GG + A K +++N + + D + G G+ Sbjct: 11 PLVNRLQDAFSAIGQNADLDLPQIAVVGG-QSAGKSSVLENFVGR-DFLPRGSGIVTRRP 68 Query: 239 -------AFTFKKVLENTEIGD--SIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADA 289 A T + + G + F++ EI + +P++ + Sbjct: 69 LVLQLVNATTEYAEFLHCK-GKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSP 127 Query: 290 FSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIV 333 + + +P G Q D + R + V K ++ Sbjct: 128 HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLI 171 >6A50-A nrPDB Length = 549 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 38/187 (20%), Positives = 66/187 (35%), Gaps = 9/187 (4%) Query: 42 AALPTIKYVLEHHPRYVVLASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGP 101 A + I +LE H +V+ + + R + L P L S+ + +G Sbjct: 276 AGIAAISQLLEGHDVVLVIGAPVFR-YVFYDPGQYLKP-GTRLISVTCDPLEAARAPMGD 333 Query: 102 EVEAAVKASAPGSVILLENL--RYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVY 159 + A + A A L+E + KVD + E V ++++ +Y Sbjct: 334 AIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIY 393 Query: 160 INDAFGTA----HRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKV 215 +N++ T R + G AAG L G L P R +A++G Sbjct: 394 LNESTSTTAQMWQRLNMRNPG-SYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSA 452 Query: 216 ADKIQLI 222 I + Sbjct: 453 NYSISAL 459 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.139 0.384 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,994,021 Number of Sequences: 36641 Number of extensions: 709239 Number of successful extensions: 2053 Number of sequences better than 10.0: 49 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 1794 Number of HSP's gapped (non-prelim): 92 length of query: 416 length of database: 10,336,785 effective HSP length: 100 effective length of query: 316 effective length of database: 6,672,685 effective search space: 2108568460 effective search space used: 2108568460 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 60 (27.7 bits)