BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00492 (218 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5HIA-A nrPDB 441 e-124 2VFA-A nrPDB 347 3e-96 2JBH-A nrPDB 306 6e-84 3OZG-A nrPDB 207 3e-54 5IPF-A nrPDB 199 5e-52 6BO7-A nrPDB 190 5e-49 1QK4-A nrPDB 162 9e-41 3HVU-A nrPDB 111 2e-25 6D9Q-A nrPDB 111 2e-25 4QYI-A nrPDB 111 2e-25 6AQO-A nrPDB 108 2e-24 4PFQ-A nrPDB 104 3e-23 4QRI-A nrPDB 100 5e-22 3ACB-A nrPDB 99 2e-21 1R3U-A nrPDB 97 5e-21 1G9T-A nrPDB 97 6e-21 3OHP-A nrPDB 97 6e-21 4RQB-A nrPDB 95 2e-20 4LYY-A nrPDB 93 7e-20 1HGX-A nrPDB 90 6e-19 5EUC-A nrPDB 89 1e-18 1PZM-A nrPDB 89 1e-18 6APT-A nrPDB 84 5e-17 5KNP-A nrPDB 79 1e-15 5ESX-A nrPDB 74 5e-14 5BQP-A nrPDB 48 3e-06 6FSP-A nrPDB 40 0.001 1VDM-A nrPDB 39 0.001 4P86-A nrPDB 39 0.001 1UFR-A nrPDB 39 0.002 1XZN-A nrPDB 36 0.011 4P83-A nrPDB 35 0.021 4P3K-A nrPDB 35 0.029 4P80-A nrPDB 35 0.032 4TWB-A nrPDB 34 0.037 4TS7-A nrPDB 34 0.044 1P4A-A nrPDB 31 0.34 5HKF-A nrPDB 31 0.36 2P1Z-A nrPDB 31 0.47 2XBU-A nrPDB 30 0.57 1U9Y-A nrPDB 30 0.94 5VOG-A nrPDB 30 1.0 1ECF-A nrPDB 29 1.3 4MB6-A nrPDB 29 1.4 3NAG-A nrPDB 29 1.5 5MP7-A nrPDB 29 1.6 4RV4-A nrPDB 28 3.5 3G6W-A nrPDB 28 4.1 4MQM-A nrPDB 28 4.4 2DY0-A nrPDB 28 4.4 5LNX-A nrPDB 27 5.6 4UG0-LN nrPDB 27 6.3 5V1Q-A nrPDB 27 6.5 2FXV-A nrPDB 27 9.1 2AEE-A nrPDB 27 9.7 >5HIA-A nrPDB Length = 224 Score = 441 bits (1135), Expect = e-124, Method: Compositional matrix adjust. Identities = 216/218 (99%), Positives = 216/218 (99%) Query: 1 MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH 60 MATRSPGVVISDDEPGYDLDLF IPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH Sbjct: 7 MATRSPGVVISDDEPGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH 66 Query: 61 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD 120 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD Sbjct: 67 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD 126 Query: 121 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG 180 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG Sbjct: 127 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG 186 Query: 181 FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 FEIPDKFVVGYALDYNEYFRDLNHV VISETGKAKYKA Sbjct: 187 FEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYKA 224 >2VFA-A nrPDB Length = 229 Score = 347 bits (889), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 169/210 (80%), Positives = 185/210 (88%) Query: 9 VISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL 68 V D+ GYDLD F IP HY + L +V +P+G+I +R E+LARDVMKEMGGHHIVALCVL Sbjct: 17 VFVKDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLARDVMKEMGGHHIVALCVL 76 Query: 69 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGK 128 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGK Sbjct: 77 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGK 136 Query: 129 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFV 188 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVA L +KRTP G+K DFVGF IPD FV Sbjct: 137 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVACLFIKRTPLWNGFKADFVGFSIPDHFV 196 Query: 189 VGYALDYNEYFRDLNHVCVISETGKAKYKA 218 VGY+LDYNE FRDL+H C++++ GK KYKA Sbjct: 197 VGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 226 >2JBH-A nrPDB Length = 225 Score = 306 bits (783), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 144/211 (68%), Positives = 177/211 (83%) Query: 7 GVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALC 66 GVVI DD PGYDL+LF P HY DLE V IPHG+I+DR ERLA+D+MK++G I+ LC Sbjct: 14 GVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLC 73 Query: 67 VLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLT 126 VLKGGYKF ADL++++K ++RNSDR + M VDFIRLKSY NDQS G++++IGGDDLSTL Sbjct: 74 VLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLA 133 Query: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDK 186 GKNVLIVED++ TG+TM+ LLS + +Y P M+KVASLLVKRT RS G++PD+ GFEIP+ Sbjct: 134 GKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNL 193 Query: 187 FVVGYALDYNEYFRDLNHVCVISETGKAKYK 217 FVVGYALDYNEYFRDLNH+CVI+E GK KY+ Sbjct: 194 FVVGYALDYNEYFRDLNHICVINEHGKEKYR 224 >3OZG-A nrPDB Length = 250 Score = 207 bits (527), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 105/213 (49%), Positives = 146/213 (68%), Gaps = 4/213 (1%) Query: 9 VISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL 68 V +D+ GYDLD F IP HY + L +V +P+G+I +R E+LA D+ K LC+L Sbjct: 36 VFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLL 95 Query: 69 KGGYKFFADLLDYIKALNRNS--DRSIPMTVD-FIRLKSYCNDQSTGDIKVIGGDDLSTL 125 KG FF LL ++ ++ S + S P+ + ++R+KSYCNDQSTG ++++ +DLS L Sbjct: 96 KGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVS-EDLSCL 154 Query: 126 TGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPD 185 GK+VLIVEDIIDTGKT+ ++++ K V +A L +KRTP G+K DFVGF IPD Sbjct: 155 KGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPD 214 Query: 186 KFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 FVVGY+LDYNE FRDL+H C++++ GK KYKA Sbjct: 215 HFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 247 >5IPF-A nrPDB Length = 250 Score = 199 bits (507), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 104/214 (48%), Positives = 143/214 (66%), Gaps = 3/214 (1%) Query: 8 VVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVM---KEMGGHHIVA 64 VVI D G+ + FC Y E L+ V IP+G+I DR E+++ +++ + I Sbjct: 30 VVIEDSFRGFPTEYFCTSPRYDECLDYVLIPNGMIKDRLEKMSMNIVDYYEACNATSITL 89 Query: 65 LCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLST 124 +CVLKGG+KF ADL+D ++ R +PM+V+F+R+KSY ND S + + G D S Sbjct: 90 MCVLKGGFKFLADLVDGLERTVRARGIVLPMSVEFVRVKSYVNDVSIHEPILTGLGDPSE 149 Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 KNVL+VEDIIDTGKT+ L+S + + K VKVASLLVKRT Y+PDFVGFE+P Sbjct: 150 YKDKNVLVVEDIIDTGKTITKLISHLDSLSTKSVKVASLLVKRTSPRNDYRPDFVGFEVP 209 Query: 185 DKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 ++FVVGYALDYN+ FRDL+H+CVI+E G+ K+ Sbjct: 210 NRFVVGYALDYNDNFRDLHHICVINEVGQKKFSV 243 >6BO7-A nrPDB Length = 238 Score = 190 bits (482), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 94/214 (43%), Positives = 140/214 (65%), Gaps = 5/214 (2%) Query: 8 VVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCV 67 + I DD+ GYD+D F IP+HY + +V IP+G++ +R E+LA D+ + +C+ Sbjct: 22 IYIKDDD-GYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICL 80 Query: 68 LKGGYKFFADLLDYIKALNRNSDRSIPMTV---DFIRLKSYCNDQSTGDIKVIGGDDLST 124 LKG FF+ LL Y+ ++ S P + ++R+KSYCNDQS I+++ +DLS Sbjct: 81 LKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSYCNDQSLDRIEIVS-EDLSC 139 Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 L K+VLIVEDIIDTGKT+ ++++ K + + L +KRTP G+K DFVGF IP Sbjct: 140 LKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIP 199 Query: 185 DKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 D FVVGY+LDYNE FRDL+H+C++++ G K++ Sbjct: 200 DAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 233 >1QK4-A nrPDB Length = 233 Score = 162 bits (411), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 85/208 (40%), Positives = 126/208 (60%), Gaps = 4/208 (1%) Query: 13 DEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGY 72 D Y+ D F +P H ++++ +P GL+ DR E+LA D+ + G + +C+LKG Sbjct: 26 DNTFYNADDFLVPPHCKPYIDKILLPGGLVKDRVEKLAYDIHRTYFGEELHIICILKGSR 85 Query: 73 KFFADLLDYIKALNRNSDRSI---PMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKN 129 FF L+DY+ + + S R P ++RLKSY ND STG + V+ DDLS K+ Sbjct: 86 GFFNLLIDYLATIQKYSGRESSVPPFFEHYVRLKSYQNDNSTGQLTVLS-DDLSIFRDKH 144 Query: 130 VLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVV 189 VLIVEDI+DTG T+ ++ PK +++A+L+ KRT RS K DFVGF I D ++V Sbjct: 145 VLIVEDIVDTGFTLTEFGERLKAVGPKSMRIATLVEKRTDRSNSLKGDFVGFSIEDVWIV 204 Query: 190 GYALDYNEYFRDLNHVCVISETGKAKYK 217 G D+NE FRD +HV V+S+ + K++ Sbjct: 205 GCCYDFNEMFRDFDHVAVLSDAARKKFE 232 >3HVU-A nrPDB Length = 204 Score = 111 bits (278), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 68/180 (37%), Positives = 107/180 (59%), Gaps = 11/180 (6%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNS 89 +D+E+V I I ++ L + ++ +A+ VLKG F ADLL + + Sbjct: 28 QDIEKVLISEEQIQEKVLELGAIIAEDYKNTVPLAIGVLKGAMPFMADLL-------KRT 80 Query: 90 DRSIPMTVDFIRLKSYCNDQ-STGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS 148 D + M DF+ + SY + STG++K++ D +++ G+++LIVEDIID+G T+ L+ Sbjct: 81 DTYLEM--DFMAVSSYGHSTVSTGEVKILKDLD-TSVEGRDILIVEDIIDSGLTLSYLVD 137 Query: 149 LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 L + K VK+ +LL K T R V K D+VGF +P +FVVGY LDY E +R+L +V V+ Sbjct: 138 LFKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVL 197 >6D9Q-A nrPDB Length = 183 Score = 111 bits (278), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 68/180 (37%), Positives = 107/180 (59%), Gaps = 11/180 (6%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNS 89 +D+E+V I I ++ L + ++ +A+ VLKG F ADLL + + Sbjct: 7 QDIEKVLISEEQIQEKVLELGAIIAEDYKNTVPLAIGVLKGAMPFMADLL-------KRT 59 Query: 90 DRSIPMTVDFIRLKSYCNDQ-STGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS 148 D + M DF+ + SY + STG++K++ D +++ G+++LIVEDIID+G T+ L+ Sbjct: 60 DTYLEM--DFMAVSSYGHSTVSTGEVKILKDLD-TSVEGRDILIVEDIIDSGLTLSYLVD 116 Query: 149 LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 L + K VK+ +LL K T R V K D+VGF +P +FVVGY LDY E +R+L +V V+ Sbjct: 117 LFKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVL 176 >4QYI-A nrPDB Length = 186 Score = 111 bits (278), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 65/182 (35%), Positives = 107/182 (58%), Gaps = 12/182 (6%) Query: 31 DLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSD 90 +++ I + ++ + LA + ++ G IV + VLKG + F ADL+ +IK Sbjct: 7 EIKDTLISEEQLQEKVKELALQIERDFEGEEIVVIAVLKGSFVFAADLIRHIKN------ 60 Query: 91 RSIPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSL 149 +T+DFI SY N ++TG +K++ D++ +TGKNV++VEDIID+G T+ L Sbjct: 61 ---DVTIDFISASSYGNQTETTGKVKLLKDIDVN-ITGKNVIVVEDIIDSGLTLHFLKDH 116 Query: 150 VRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVC-VI 208 + PK +K +LL K R V ++VGF+IPD+F+VGY +D E +R+L + V+ Sbjct: 117 FFMHKPKALKFCTLLDKPERRKVDLTAEYVGFQIPDEFIVGYGIDCAEKYRNLPFIASVV 176 Query: 209 SE 210 +E Sbjct: 177 TE 178 >6AQO-A nrPDB Length = 272 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 8/159 (5%) Query: 62 IVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSY-CNDQSTGDIKVIGGD 120 ++ + VLKG Y F AD++ Y+ D +P VDFIR+ SY +S+G ++V+ Sbjct: 118 LIIISVLKGSYIFTADMVRYL------GDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNL 171 Query: 121 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR-QYNPKMVKVASLLVKRTPRSVGYKPDFV 179 + LTGK+VLI+EDI DTG+TM+ L+ +R +Y P +KV L+ K R V +KP+FV Sbjct: 172 RFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFV 231 Query: 180 GFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 P ++VVGY + N+ +R+ HV V+ +Y + Sbjct: 232 CLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPS 270 >4PFQ-A nrPDB Length = 207 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 69/188 (36%), Positives = 104/188 (55%), Gaps = 13/188 (6%) Query: 26 NHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKAL 85 H D++RV + I DR L + + V + VL+G ADL Sbjct: 27 THPHPDVDRVLLDEQQIRDRLAELGEQIAADYAEEPPVLVGVLRGAVMVMADL------- 79 Query: 86 NRNSDRSIPMTVDFIRLKSY-CNDQSTGDIKVIGGDDLS-TLTGKNVLIVEDIIDTGKTM 143 R D + M D++ + SY +S+G ++++ DLS +T +NVLIVEDIID+G T+ Sbjct: 80 ARQIDLKVEM--DWMAVSSYGSGTKSSGVVRIL--KDLSGDITDRNVLIVEDIIDSGLTL 135 Query: 144 QTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLN 203 + LLS +R PK V+VA+LL K V ++GF+IP +FV+GY LDY E +R+L Sbjct: 136 KWLLSNLRSRGPKSVEVAALLRKPDAARVDIDVKYIGFDIPSEFVIGYGLDYAENYRNLP 195 Query: 204 HVCVISET 211 +V V+S + Sbjct: 196 YVGVLSRS 203 >4QRI-A nrPDB Length = 207 Score = 100 bits (249), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 58/177 (32%), Positives = 105/177 (59%), Gaps = 15/177 (8%) Query: 42 IMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVD--F 99 I + + LA + ++ + + +CVLKGG FF DL R IP +V+ F Sbjct: 42 ISQKVKSLALQISEDYKKLNPIFICVLKGGVYFFTDL-----------TREIPFSVEINF 90 Query: 100 IRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVK 159 ++ +SY STG I+++ D+ L+ ++V+IVEDI+DTG T+Q L+ + NP ++ Sbjct: 91 VQARSYSGTVSTGKIELLKDIDID-LSDRHVIIVEDILDTGFTLQYLVRHIFTRNPASLE 149 Query: 160 VASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKY 216 + +LL+K ++ + ++G+ IPD+F+VGY LD++ +R+L + V+ E G+ ++ Sbjct: 150 IVTLLLKERKDTLEFPVKYIGWRIPDEFLVGYGLDFDGRYRNLPDIHVL-EPGEPQF 205 >3ACB-A nrPDB Length = 181 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 59/168 (35%), Positives = 95/168 (56%), Gaps = 11/168 (6%) Query: 42 IMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIR 101 I R E L ++ ++ G +CVL G + F ADL+ I +P+T+DFI Sbjct: 19 IKKRVEELGGEIARDYQGKTPHLICVLNGAFIFMADLVRAI---------PLPLTMDFIA 69 Query: 102 LKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKV 160 + SY N +S+G+++++ D + G++V++VEDI+DTG T+ LL + P V+V Sbjct: 70 ISSYGNAFKSSGEVELLK-DLRLPIHGRDVIVVEDIVDTGLTLSYLLDYLEARKPASVRV 128 Query: 161 ASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 A+LL K + R V ++GFEI D +V GY LD ++ R+L + I Sbjct: 129 AALLSKPSRRQVEVPIHYLGFEIEDAYVYGYGLDRAQFDRNLPFITSI 176 >1R3U-A nrPDB Length = 205 Score = 97.1 bits (240), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 63/180 (35%), Positives = 102/180 (56%), Gaps = 11/180 (6%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNS 89 ED+E + I + + + L + ++ G +V + VLKG F + L+R Sbjct: 30 EDIEEILITEEQLKAKVKELGEMITRDYEGKDLVLIGVLKGAIMFMS-------GLSRAI 82 Query: 90 DRSIPMTVDFIRLKSYCNDQST-GDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS 148 D +P+++DF+ + SY + + G +K+I D+ + GK+VLIVEDIID+G T+ L Sbjct: 83 D--LPLSIDFLAVSSYGSSTKSSGIVKIIKDHDID-IEGKDVLIVEDIIDSGLTLAYLRE 139 Query: 149 LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 + P+ +K+ ++L K R K D+ GF+IPDKFVVGY LDY E +R+L + V+ Sbjct: 140 TLLGRKPRSLKICTILDKPERREADVKVDYCGFKIPDKFVVGYGLDYAEKYRNLPFIGVL 199 >1G9T-A nrPDB Length = 182 Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 60/174 (34%), Positives = 94/174 (54%), Gaps = 13/174 (7%) Query: 35 VFIPHGLIMDRTERLARDVMKEM--GGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRS 92 V IP I R L R + + G +V + +L+G + F ADL ++ Sbjct: 11 VMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQ--------- 61 Query: 93 IPMTVDFIRLKSYCNDQSTG-DIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR 151 + VDF+ SY + ST D+K++ D + GK+VLIVEDIID+G T+ + ++ Sbjct: 62 VSHEVDFMTASSYGSGMSTTRDLKILKDLD-EDIRGKDVLIVEDIIDSGNTLSKVREILS 120 Query: 152 QYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHV 205 PK + + +LL K + R V +F+GF IPD+FVVGY +DY + +R L ++ Sbjct: 121 LREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYI 174 >3OHP-A nrPDB Length = 177 Score = 96.7 bits (239), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 61/175 (34%), Positives = 97/175 (55%), Gaps = 16/175 (9%) Query: 35 VFIPHGLIMDRTERLARDVMKE-MGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSI 93 V I + R L + + + G +V + +L+G + F ADL R I Sbjct: 7 VMISEQEVAQRIRELGQQITEHYQGSSDLVLVGLLRGSFVFMADLA-----------RQI 55 Query: 94 PMT--VDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLV 150 +T VDF+ SY N QS+ D++++ D + GK+VL+VEDIIDTG T+ + ++ Sbjct: 56 HLTHQVDFMTASSYGNSMQSSRDVRILKDLD-DDIKGKDVLLVEDIIDTGNTLNKVKEIL 114 Query: 151 RQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHV 205 PK +++ +LL K T R V + ++VGFEIPD+FVVG +DY + +R L ++ Sbjct: 115 ALREPKSIRICTLLDKPTRREVDVEVNWVGFEIPDEFVVGVGIDYAQKYRHLPYI 169 >4RQB-A nrPDB Length = 186 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 56/176 (31%), Positives = 101/176 (57%), Gaps = 11/176 (6%) Query: 31 DLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSD 90 DL+ V + I + + L + K+ G +V + +LKG F +DL+ I Sbjct: 11 DLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDT------ 64 Query: 91 RSIPMTVDFIRLKSY-CNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSL 149 +++DF+ + SY +STG++++I D S++ K+VLI+EDI++TG T++++ L Sbjct: 65 ---HLSIDFMDVSSYHGGTESTGEVQIIK-DLGSSIENKDVLIIEDILETGTTLKSITEL 120 Query: 150 VRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHV 205 ++ +++ +LL K R + +VG +IPD+FVVGY LDY E +R+L ++ Sbjct: 121 LQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYI 176 >4LYY-A nrPDB Length = 199 Score = 93.2 bits (230), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 56/162 (34%), Positives = 91/162 (56%), Gaps = 17/162 (10%) Query: 52 DVMKEMGGHH------IVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSY 105 D++ E H ++ + +LKG F ADL IK + +DF+ + SY Sbjct: 41 DILAEQINAHYADSDRLLMVGLLKGSVVFMADLCRRIKG---------HVEIDFMSVSSY 91 Query: 106 CNDQSTG-DIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 N+ S+ D+K++ D S + G++VLIVED+ID+G T+ + ++ PK + + +LL Sbjct: 92 GNEMSSSRDVKILK-DVQSEIQGRDVLIVEDLIDSGNTLNKVRDMLLLREPKSLALCTLL 150 Query: 165 VKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVC 206 K R V DF+GF IPD+F+VGY +DY E +R+L ++ Sbjct: 151 DKPERREVDVPVDFIGFTIPDEFIVGYGIDYAEQYRNLPYIA 192 >1HGX-A nrPDB Length = 183 Score = 90.1 bits (222), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 57/183 (31%), Positives = 97/183 (53%), Gaps = 11/183 (6%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNS 89 +DLERV I R LA ++ + + V +CVL G F+ DLL ++ Sbjct: 8 DDLERVLYNQDDIQKRIRELAAELTEFYEDKNPVMICVLTGAVFFYTDLLKHL------- 60 Query: 90 DRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSL 149 + D+I SY +STG++ I D + + G++VL+VEDIIDTG TM LL+ Sbjct: 61 --DFQLEPDYIICSSYSGTKSTGNL-TISKDLKTNIEGRHVLVVEDIIDTGLTMYQLLNN 117 Query: 150 VRQYNPKMVKVASLLVKRTPRSVGYKP-DFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 ++ P +KV +L K + P D+ GF + +++++GY D++ +R+L + ++ Sbjct: 118 LQMRKPASLKVCTLCDKDIGKKAYDVPIDYCGFVVENRYIIGYGFDFHNKYRNLPVIGIL 177 Query: 209 SET 211 E+ Sbjct: 178 KES 180 >5EUC-A nrPDB Length = 229 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 64/203 (31%), Positives = 107/203 (52%), Gaps = 16/203 (7%) Query: 24 IPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGG-------HHIVALCVLKGGYKFFA 76 +P Y E E++ I R + +A+ + + G + +V + VLKG + F A Sbjct: 1 MPREY-EFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTA 59 Query: 77 DLLDYIKALNRNSDRSIPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVED 135 DL +AL D ++P+ ++FI + SY S+G ++++ D ++ G +VLIVED Sbjct: 60 DL---CRAL---CDFNVPVRMEFICVSSYGEGLTSSGQVRMLL-DTRHSIEGHHVLIVED 112 Query: 136 IIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDY 195 I+DT T+ L + P +K LL KR R V + D+V IP+ FV+GY LDY Sbjct: 113 IVDTALTLNYLYHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDY 172 Query: 196 NEYFRDLNHVCVISETGKAKYKA 218 ++ +R+L + V+ A+ +A Sbjct: 173 DDTYRELRDIVVLRPEVYAEREA 195 >1PZM-A nrPDB Length = 211 Score = 89.0 bits (219), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 52/184 (28%), Positives = 97/184 (52%), Gaps = 14/184 (7%) Query: 34 RVFIPHGLIMDRTERLARDVMKEMGGHHIVA------LCVLKGGYKFFADLLDYIKALNR 87 R + + T + A+ + + H+ A LCVLKG + F ADL ++ Sbjct: 25 RTLVTQEQVWAATAKCAKKIAADYKDFHLTADNPLYLLCVLKGSFIFTADLARFL----- 79 Query: 88 NSDRSIPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTL 146 +D +P+ V+FI SY + +++G ++++ D ++ +++++VEDI+D+ T+Q L Sbjct: 80 -ADEGVPVKVEFICASSYGSGVETSGQVRMLL-DVRDSVENRHIMLVEDIVDSAITLQYL 137 Query: 147 LSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVC 206 + + P +K LL K + R V D+ IP FV+GY +D+ E +R+L +C Sbjct: 138 MRFMLAKKPASLKTVVLLDKPSGRKVDVLVDYPVITIPRAFVIGYGMDFAESYRELRDIC 197 Query: 207 VISE 210 V+ + Sbjct: 198 VLKK 201 >6APT-A nrPDB Length = 216 Score = 83.6 bits (205), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 47/148 (31%), Positives = 87/148 (58%), Gaps = 8/148 (5%) Query: 62 IVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCND-QSTGDIKVIGGD 120 +V + VLKG + F AD++ + D +P V+F+R SY +D +S G + V D Sbjct: 53 LVIVSVLKGSFVFTADMVRIL------GDFGVPTRVEFLRASSYGHDTKSCGRVDV-KAD 105 Query: 121 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG 180 L + GK+VL++EDI+DT T++ ++ +++ P +K + K R + + ++V Sbjct: 106 GLCDIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVV 165 Query: 181 FEIPDKFVVGYALDYNEYFRDLNHVCVI 208 ++P+ FVVGY LDY++ +R++ V ++ Sbjct: 166 ADVPNVFVVGYGLDYDQSYREVRDVVIL 193 >5KNP-A nrPDB Length = 207 Score = 79.0 bits (193), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 15/184 (8%) Query: 28 YAEDLERVFIPHGLIMDRTERLARDV------MKEMGGHHIVALCVLKGGYKFFADLLDY 81 Y D++ V + I R L + + G ++ + VLKG F DL Sbjct: 24 YPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARA 83 Query: 82 IKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGK 141 I +P +F+ + SY + S+ + I D + G++VLIVED++D+G Sbjct: 84 IP---------VPTQFEFMAVSSYGSSTSSSGVVRILKDLDRDIHGRDVLIVEDVVDSGL 134 Query: 142 TMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRD 201 T+ L + NP+ ++V +LL K + +VGF+IP+ FVVGY LDY+E +RD Sbjct: 135 TLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRD 194 Query: 202 LNHV 205 L+++ Sbjct: 195 LSYI 198 >5ESX-A nrPDB Length = 195 Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 14/171 (8%) Query: 47 ERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYC 106 +R+A + + + + V +CV+ GG +LL + P+ VD++ Y Sbjct: 34 DRMAIKIHETLQDKNPVIICVMVGGLVPLGNLLHRL---------DFPLEVDYVHATRYR 84 Query: 107 NDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL-- 164 D + GDI + S L G+ VL+V+DI+D G T+ +++ ++ V A L+ Sbjct: 85 GDLTGGDI-LWKVRPSSNLAGRTVLVVDDILDGGITLAAIINEIKAMGAAEVYSAVLVDK 143 Query: 165 -VKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKA 214 KR P + K DFVG ++ D ++ GY +DY+EY R+ + ++ +A Sbjct: 144 YRKRVPNGL-QKADFVGLQVEDHYIFGYGMDYHEYLRNAPGIFIVHPDHEA 193 >5BQP-A nrPDB Length = 179 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 33/111 (29%), Positives = 62/111 (55%), Gaps = 5/111 (4%) Query: 97 VDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPK 156 + +I +K Y + T VI +L GK VL+V+D+ DTG+T++ + +++ +NP Sbjct: 56 IRYIDIKFYRSVGKTESKPVIRSVYTDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPA 115 Query: 157 MVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCV 207 V A+L +K + + PDF +I DK+++ + D + R+ ++V V Sbjct: 116 KVMTAALYLKPWSKRI---PDFYYKQI-DKWII-FPWDKWDVVRENSNVPV 161 >6FSP-A nrPDB Length = 174 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 4/67 (5%) Query: 116 VIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPR----S 171 V+ G D+ + GK V IV+D++ TG T+ L L+ ++V V ++ + TPR + Sbjct: 108 VLDGADIPRVRGKKVAIVDDVVSTGSTLAGLRELIESVGGEVVAVLAVFTEGTPRQDVVA 167 Query: 172 VGYKPDF 178 +G+ P F Sbjct: 168 LGHLPLF 174 >1VDM-A nrPDB Length = 153 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 6/97 (6%) Query: 93 IPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQ 152 IP+ V I +K Y G+ VI L K V+IV+D+ DTGKT++ ++ V++ Sbjct: 51 IPLKV--IDVKFYKGIDERGEKPVITIPIHGDLKDKRVVIVDDVSDTGKTLEVVIEEVKK 108 Query: 153 YNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVV 189 K +K+A L +K V PD+ F +K++V Sbjct: 109 LGAKEIKIACLAMKPWTSVV---PDYYVFRT-EKWIV 141 >4P86-A nrPDB Length = 183 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 35/128 (27%), Positives = 68/128 (53%), Gaps = 15/128 (11%) Query: 66 CVLKG----GYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCND---QSTGDIKVIG 118 C+L G G L + I+ + N P+TV I + Y +D +++ D ++ Sbjct: 35 CILVGIKTRGIYLAKRLAERIEQIEGN-----PVTVGEIDITLYRDDLSKKTSNDEPLVK 89 Query: 119 GDDLST-LTGKNVLIVEDIIDTGKTMQTLL-SLVRQYNPKMVKVASLLVKRTPRSVGYKP 176 G D+ +T + V++V+D++ TG+T++ + +LV P +++A +LV R R + + Sbjct: 90 GADIPVDITDQKVILVDDVLYTGRTVRAGMDALVDVGRPSSIQLA-VLVDRGHRELPIRA 148 Query: 177 DFVGFEIP 184 D++G IP Sbjct: 149 DYIGKNIP 156 >1UFR-A nrPDB Length = 181 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 39/61 (63%), Gaps = 2/61 (3%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLL-SLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEI 183 LTGK +++V+D++ TG+T + L +L+ P+ + +A +LV R R + + DFVG + Sbjct: 94 LTGKAIVLVDDVLYTGRTARAALDALIDLGRPRRIYLA-VLVDRGHRELPIRADFVGKNV 152 Query: 184 P 184 P Sbjct: 153 P 153 >1XZN-A nrPDB Length = 179 Score = 36.2 bits (82), Expect = 0.011, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 38/61 (62%), Gaps = 2/61 (3%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQY-NPKMVKVASLLVKRTPRSVGYKPDFVGFEI 183 +T +NV++V+D++ TG+T++ + V P +++A +LV R R + + DFVG + Sbjct: 95 VTERNVILVDDVLFTGRTVRAAMDAVMDLGRPARIQLA-VLVDRGHRELPIRADFVGKNV 153 Query: 184 P 184 P Sbjct: 154 P 154 >4P83-A nrPDB Length = 182 Score = 35.4 bits (80), Expect = 0.021, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 38/61 (62%), Gaps = 2/61 (3%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQY-NPKMVKVASLLVKRTPRSVGYKPDFVGFEI 183 +T +NV++V+D++ TG+T++ + V P +++A +LV R R + + DFVG + Sbjct: 97 VTERNVILVDDVLFTGRTVRAGMDAVMDLGRPARIQLA-VLVDRGHRELPIRADFVGKNV 155 Query: 184 P 184 P Sbjct: 156 P 156 >4P3K-A nrPDB Length = 180 Score = 34.7 bits (78), Expect = 0.029, Method: Compositional matrix adjust. Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 23/148 (15%) Query: 48 RLARDVMKEMGGHHIVALCVLKG----GYKFFADLLDYIKALNRNSDRSIPMTVDFIRLK 103 R+A ++++ G V CVL G G L + I+ + P+ V I + Sbjct: 20 RIAHEIIERNKG---VDNCVLVGIKTRGIYLAKRLAERIEQIEGK-----PVPVGEIDIT 71 Query: 104 SYCNDQSTGDIK--VIGGDDLST-LTGKNVLIVEDIIDTGKT----MQTLLSLVRQYNPK 156 Y +D + K ++ G D+ +T K V++V+D++ TG+T M L+ L R P Sbjct: 72 LYRDDLTVTSNKEPLVKGTDIPVDITDKKVILVDDVLYTGRTVRAGMDALMDLGR---PS 128 Query: 157 MVKVASLLVKRTPRSVGYKPDFVGFEIP 184 +++A +LV R R + + D+VG +P Sbjct: 129 QIQLA-VLVDRGHRELPIRADYVGKNVP 155 >4P80-A nrPDB Length = 180 Score = 34.7 bits (78), Expect = 0.032, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 2/70 (2%) Query: 116 VIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLL-SLVRQYNPKMVKVASLLVKRTPRSVGY 174 V G D +T + V++V+D++ TG+T++ + +LV P +++A +LV R R + Sbjct: 87 VKGADIPVDITDQKVILVDDVLYTGRTVRAAMDALVDVGRPSSIQLA-VLVDRGHRELPI 145 Query: 175 KPDFVGFEIP 184 + D++G IP Sbjct: 146 RADYIGKNIP 155 >4TWB-A nrPDB Length = 291 Score = 34.3 bits (77), Expect = 0.037, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 41/74 (55%), Gaps = 7/74 (9%) Query: 108 DQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVAS---LL 164 D++TG++++ +++ L GK+V+I++DII TG T+ L K V A+ LL Sbjct: 191 DRTTGEVRIKEAPNIN-LKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLL 249 Query: 165 V---KRTPRSVGYK 175 V K R VG K Sbjct: 250 VGGAKERLREVGVK 263 >4TS7-A nrPDB Length = 210 Score = 34.3 bits (77), Expect = 0.044, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 5/75 (6%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQ-YNPKMVKVASL-LVKRTPRSVGYKPDFVGFE 182 L+ KNVLI++DI DTG +++ V + + P VK A+L +K + + PD+ E Sbjct: 86 LSDKNVLIIDDITDTGDSIELARKYVMENFRPTEVKTATLQYIKPAAKII---PDYYAEE 142 Query: 183 IPDKFVVGYALDYNE 197 I Y +Y E Sbjct: 143 IVSWAWFMYPWNYWE 157 >1P4A-A nrPDB Length = 285 Score = 31.2 bits (69), Expect = 0.34, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 31/55 (56%) Query: 110 STGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 S+ I+ + S TG NVLI++D + G T+ +++L+ ++N + + L+ Sbjct: 179 SSNRIQTMSLAKRSMKTGSNVLIIDDFMKAGGTINGMINLLDEFNANVAGIGVLV 233 >5HKF-A nrPDB Length = 189 Score = 31.2 bits (69), Expect = 0.36, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 28/46 (60%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRT 168 S +TG+ VL+VED TG + T + V+ ++V VA+++ + T Sbjct: 119 SEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRAT 164 >2P1Z-A nrPDB Length = 180 Score = 30.8 bits (68), Expect = 0.47, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 27/44 (61%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRT 168 + GK VL+VED TG + T + +R+ ++V VA+++ + T Sbjct: 112 VVGKKVLVVEDTTTTGNSPLTAVKALREAGAEVVGVATVVDRAT 155 >2XBU-A nrPDB Length = 221 Score = 30.4 bits (67), Expect = 0.57, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 L GKNVLIV+++ DT T+ LS + + + K + +++P K +F F + Sbjct: 101 LVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKAKGIDTEKSPE---MKTNFGIFVLH 157 Query: 185 DK 186 DK Sbjct: 158 DK 159 >1U9Y-A nrPDB Length = 284 Score = 29.6 bits (65), Expect = 0.94, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%) Query: 128 KNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVA 161 ++V IV+DII TG TM T + L+++ K + A Sbjct: 206 RDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAA 239 >5VOG-A nrPDB Length = 183 Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 13/87 (14%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVK------RTPRSVGYKP 176 L GKNVL+V+++ D+ TM+ L + + + V VA L K + P + Y Sbjct: 94 EVLRGKNVLVVDEVDDSRVTMEFCLKELLKEDFDTVGVAVLHEKIKAKAGKIPEGIPY-- 151 Query: 177 DFVGFEIPDKFVVGY---ALDYNEYFR 200 F G + D + + Y ALD +E+ R Sbjct: 152 -FSGITVED-WWINYPWDALDIDEHNR 176 >1ECF-A nrPDB Length = 504 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 22/35 (62%) Query: 128 KNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVAS 162 KNVL+V+D I G T + ++ + R+ K V +AS Sbjct: 360 KNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLAS 394 >4MB6-A nrPDB Length = 187 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 25/38 (65%) Query: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 G VL+V+D++ TG T++ + L+R+ ++V A ++ Sbjct: 123 GDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFII 160 >3NAG-A nrPDB Length = 286 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 24/39 (61%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL 163 + GK +LIV+DII TG T+ L+R+ + V+++ Sbjct: 201 VNGKKLLIVDDIISTGGTIAKSSGLLREKGASKIYVSAV 239 >5MP7-A nrPDB Length = 326 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVAS 162 GK ++ +D+IDTG T+ ++L+R+ K V +A+ Sbjct: 223 GKTCILTDDMIDTGGTIAGAVNLLREDGAKDVIIAA 258 >4RV4-A nrPDB Length = 234 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 11/39 (28%), Positives = 24/39 (61%) Query: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLV 165 G+ V++VED+I TG + T + +R+ +++ + S+ Sbjct: 137 GQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFT 175 >3G6W-A nrPDB Length = 216 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 22/36 (61%) Query: 129 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 NV+I + +I T TM +L V + NPK + + S++ Sbjct: 135 NVIIADPMIATASTMLKVLEEVVKANPKRIYIVSII 170 >4MQM-A nrPDB Length = 304 Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 4/52 (7%) Query: 154 NPKMVKVASLLVKRTPRSV----GYKPDFVGFEIPDKFVVGYALDYNEYFRD 201 N MV++ L+ T V G D G IP KF+ G L N+ FRD Sbjct: 191 NDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGLTLRTNQTFRD 242 >2DY0-A nrPDB Length = 190 Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust. Identities = 11/38 (28%), Positives = 24/38 (63%) Query: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 G VL+V+D++ TG T++ + L+R+ ++ A ++ Sbjct: 126 GDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFII 163 >5LNX-A nrPDB Length = 379 Score = 27.3 bits (59), Expect = 5.6, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 32/60 (53%) Query: 38 PHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTV 97 P IM++T+ ++K+MG H ++ + V + AD++ YI A++ S S + V Sbjct: 24 PAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGV 83 >4UG0-LN nrPDB Length = 204 Score = 26.9 bits (58), Expect = 6.3, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 9/63 (14%) Query: 37 IPHGLIMDRTERLARDVMKEMGGHHIVALCVLK-------GGYKFFADLL--DYIKALNR 87 + HG+ + R + V +E G H AL VL YKFF +L + KA+ R Sbjct: 85 VHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRR 144 Query: 88 NSD 90 N D Sbjct: 145 NPD 147 >5V1Q-A nrPDB Length = 459 Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust. Identities = 23/114 (20%), Positives = 45/114 (39%), Gaps = 21/114 (18%) Query: 50 ARDVMKEMGGHHIVAL-----------CVLKGGYKFFADLLDYIKALNRNSDRSIPMTVD 98 AR + ++ H+I++ C LK G+ F A+ DR+ D Sbjct: 110 ARKHVAKLKKHNILSFPLELVIYPSMYCDLKCGFCFLAN----------REDRNAKPAKD 159 Query: 99 FIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQ 152 + R+ D + ++GG+ N+LI + + T+ T L+++ Sbjct: 160 WERILRQAKDNGVLSVSILGGEPTRYFDIDNLLIACEELKIKTTITTNAQLIKK 213 >2FXV-A nrPDB Length = 194 Score = 26.6 bits (57), Expect = 9.1, Method: Compositional matrix adjust. Identities = 17/76 (22%), Positives = 36/76 (47%), Gaps = 2/76 (2%) Query: 91 RSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLV 150 +S+ +T + + Y + T + G LS +VLI++D + G+ L+S+V Sbjct: 83 KSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSD--QDHVLIIDDFLANGQAAHGLVSIV 140 Query: 151 RQYNPKMVKVASLLVK 166 +Q + + ++ K Sbjct: 141 KQAGASIAGIGIVIEK 156 >2AEE-A nrPDB Length = 211 Score = 26.6 bits (57), Expect = 9.7, Method: Compositional matrix adjust. Identities = 17/77 (22%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Query: 95 MTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYN 154 MT+ F ++S D G+ ++ G L G+ ++I+ED+I TG ++ + + Sbjct: 90 MTLPFAYIRSKPKDHGAGN-QIEG----RVLKGQKMVIIEDLISTGGSVLDAAAAASREG 144 Query: 155 PKMVKVASLLVKRTPRS 171 ++ V ++ P++ Sbjct: 145 ADVLGVVAIFTYELPKA 161 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5HIA-A nrPDB 314 2e-86 2VFA-A nrPDB 298 1e-81 2JBH-A nrPDB 284 2e-77 3OZG-A nrPDB 269 7e-73 6BO7-A nrPDB 254 2e-68 5IPF-A nrPDB 249 9e-67 1QK4-A nrPDB 242 9e-65 5EUC-A nrPDB 211 1e-55 3HVU-A nrPDB 210 3e-55 4RQB-A nrPDB 209 6e-55 4PFQ-A nrPDB 209 8e-55 6D9Q-A nrPDB 208 1e-54 4QYI-A nrPDB 205 8e-54 1R3U-A nrPDB 204 2e-53 3ACB-A nrPDB 200 5e-52 1HGX-A nrPDB 198 2e-51 3OHP-A nrPDB 197 3e-51 1PZM-A nrPDB 197 4e-51 1G9T-A nrPDB 195 1e-50 4LYY-A nrPDB 192 1e-49 4QRI-A nrPDB 191 2e-49 6AQO-A nrPDB 189 1e-48 6APT-A nrPDB 184 2e-47 5KNP-A nrPDB 179 7e-46 5ESX-A nrPDB 163 4e-41 5BQP-A nrPDB 105 2e-23 4P86-A nrPDB 101 3e-22 1VDM-A nrPDB 96 9e-21 1UFR-A nrPDB 78 2e-15 6FSP-A nrPDB 59 2e-09 Sequences not found previously or not previously below threshold: 4P80-A nrPDB 97 5e-21 4P3K-A nrPDB 96 1e-20 4P83-A nrPDB 88 4e-18 1XZN-A nrPDB 83 1e-16 5IAO-A nrPDB 62 3e-10 1DQP-A nrPDB 61 3e-10 4TS7-A nrPDB 55 3e-08 5XTK-A nrPDB 53 9e-08 4JLS-A nrPDB 53 9e-08 5VOG-A nrPDB 48 3e-06 4TWB-A nrPDB 44 4e-05 1ZN9-A nrPDB 43 7e-05 2XBU-A nrPDB 42 2e-04 2E55-A nrPDB 41 4e-04 5MP7-A nrPDB 40 8e-04 1U9Y-A nrPDB 40 0.001 1ECF-A nrPDB 39 0.002 4S2U-A nrPDB 39 0.002 1I5E-A nrPDB 38 0.003 6NFE-A nrPDB 38 0.004 3NAG-A nrPDB 38 0.004 1DKU-A nrPDB 38 0.004 5HKF-A nrPDB 38 0.004 2EHJ-A nrPDB 37 0.005 1P4A-A nrPDB 37 0.007 3QW4-B nrPDB 36 0.009 4M0K-A nrPDB 36 0.012 2P1Z-A nrPDB 36 0.012 1WD5-A nrPDB 36 0.014 3DAH-A nrPDB 35 0.040 3G6W-A nrPDB 34 0.045 5T3O-A nrPDB 33 0.12 1VCH-A nrPDB 33 0.15 4MB6-A nrPDB 32 0.16 1AO0-A nrPDB 31 0.33 4RV4-A nrPDB 31 0.44 5ZYW-A nrPDB 30 0.72 5ZYT-A nrPDB 30 0.72 2FXV-A nrPDB 30 0.78 4LZA-A nrPDB 30 0.84 4AXH-A nrPDB 30 0.86 5Z0Y-A nrPDB 30 0.90 2DY0-A nrPDB 30 0.95 3N2L-A nrPDB 30 1.1 1O5O-A nrPDB 30 1.1 2WNS-A nrPDB 30 1.1 1OPR-A nrPDB 29 1.3 4G5H-A nrPDB 29 1.7 4WN3-A nrPDB 29 1.8 2YCL-A nrPDB 29 1.8 4PAW-A nrPDB 29 1.9 5YW2-A nrPDB 29 2.2 4J5U-A nrPDB 28 2.4 4QDF-B nrPDB 28 2.7 3QUP-A nrPDB 28 2.9 2GQ0-A nrPDB 28 3.9 1L1R-A nrPDB 28 3.9 2OEL-A nrPDB 28 4.5 6MZC-R nrPDB 28 4.9 1MGT-A nrPDB 27 5.3 1Y4U-A nrPDB 27 5.5 2IOQ-A nrPDB 27 5.6 1H3O-B nrPDB 27 5.8 5BO5-A nrPDB 27 5.8 3KJP-A nrPDB 26 8.8 >5HIA-A nrPDB Length = 224 Score = 314 bits (804), Expect = 2e-86, Method: Composition-based stats. Identities = 216/218 (99%), Positives = 216/218 (99%) Query: 1 MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH 60 MATRSPGVVISDDEPGYDLDLF IPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH Sbjct: 7 MATRSPGVVISDDEPGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH 66 Query: 61 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD 120 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD Sbjct: 67 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD 126 Query: 121 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG 180 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG Sbjct: 127 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG 186 Query: 181 FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 FEIPDKFVVGYALDYNEYFRDLNHV VISETGKAKYKA Sbjct: 187 FEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYKA 224 >2VFA-A nrPDB Length = 229 Score = 298 bits (763), Expect = 1e-81, Method: Composition-based stats. Identities = 169/210 (80%), Positives = 185/210 (88%) Query: 9 VISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL 68 V D+ GYDLD F IP HY + L +V +P+G+I +R E+LARDVMKEMGGHHIVALCVL Sbjct: 17 VFVKDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLARDVMKEMGGHHIVALCVL 76 Query: 69 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGK 128 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGK Sbjct: 77 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGK 136 Query: 129 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFV 188 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVA L +KRTP G+K DFVGF IPD FV Sbjct: 137 NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVACLFIKRTPLWNGFKADFVGFSIPDHFV 196 Query: 189 VGYALDYNEYFRDLNHVCVISETGKAKYKA 218 VGY+LDYNE FRDL+H C++++ GK KYKA Sbjct: 197 VGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 226 >2JBH-A nrPDB Length = 225 Score = 284 bits (726), Expect = 2e-77, Method: Composition-based stats. Identities = 144/212 (67%), Positives = 177/212 (83%) Query: 7 GVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALC 66 GVVI DD PGYDL+LF P HY DLE V IPHG+I+DR ERLA+D+MK++G I+ LC Sbjct: 14 GVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLC 73 Query: 67 VLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLT 126 VLKGGYKF ADL++++K ++RNSDR + M VDFIRLKSY NDQS G++++IGGDDLSTL Sbjct: 74 VLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLA 133 Query: 127 GKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDK 186 GKNVLIVED++ TG+TM+ LLS + +Y P M+KVASLLVKRT RS G++PD+ GFEIP+ Sbjct: 134 GKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNL 193 Query: 187 FVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 FVVGYALDYNEYFRDLNH+CVI+E GK KY+ Sbjct: 194 FVVGYALDYNEYFRDLNHICVINEHGKEKYRV 225 >3OZG-A nrPDB Length = 250 Score = 269 bits (688), Expect = 7e-73, Method: Composition-based stats. Identities = 105/213 (49%), Positives = 146/213 (68%), Gaps = 4/213 (1%) Query: 9 VISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL 68 V +D+ GYDLD F IP HY + L +V +P+G+I +R E+LA D+ K LC+L Sbjct: 36 VFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLL 95 Query: 69 KGGYKFFADLLDYIKALNRNS--DRSIPMTVD-FIRLKSYCNDQSTGDIKVIGGDDLSTL 125 KG FF LL ++ ++ S + S P+ + ++R+KSYCNDQSTG ++++ +DLS L Sbjct: 96 KGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVS-EDLSCL 154 Query: 126 TGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPD 185 GK+VLIVEDIIDTGKT+ ++++ K V +A L +KRTP G+K DFVGF IPD Sbjct: 155 KGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPD 214 Query: 186 KFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 FVVGY+LDYNE FRDL+H C++++ GK KYKA Sbjct: 215 HFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKA 247 >6BO7-A nrPDB Length = 238 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 92/213 (43%), Positives = 138/213 (64%), Gaps = 4/213 (1%) Query: 9 VISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL 68 + D+ GYD+D F IP+HY + +V IP+G++ +R E+LA D+ + +C+L Sbjct: 22 IYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICLL 81 Query: 69 KGGYKFFADLLDYIKALNRNSDRSIPMTV---DFIRLKSYCNDQSTGDIKVIGGDDLSTL 125 KG FF+ LL Y+ ++ S P + ++R+KSYCNDQS I+++ +DLS L Sbjct: 82 KGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSYCNDQSLDRIEIVS-EDLSCL 140 Query: 126 TGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPD 185 K+VLIVEDIIDTGKT+ ++++ K + + L +KRTP G+K DFVGF IPD Sbjct: 141 KDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIPD 200 Query: 186 KFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 FVVGY+LDYNE FRDL+H+C++++ G K++ Sbjct: 201 AFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 233 >5IPF-A nrPDB Length = 250 Score = 249 bits (635), Expect = 9e-67, Method: Composition-based stats. Identities = 104/214 (48%), Positives = 142/214 (66%), Gaps = 3/214 (1%) Query: 8 VVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGG---HHIVA 64 VVI D G+ + FC Y E L+ V IP+G+I DR E+++ +++ I Sbjct: 30 VVIEDSFRGFPTEYFCTSPRYDECLDYVLIPNGMIKDRLEKMSMNIVDYYEACNATSITL 89 Query: 65 LCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLST 124 +CVLKGG+KF ADL+D ++ R +PM+V+F+R+KSY ND S + + G D S Sbjct: 90 MCVLKGGFKFLADLVDGLERTVRARGIVLPMSVEFVRVKSYVNDVSIHEPILTGLGDPSE 149 Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 KNVL+VEDIIDTGKT+ L+S + + K VKVASLLVKRT Y+PDFVGFE+P Sbjct: 150 YKDKNVLVVEDIIDTGKTITKLISHLDSLSTKSVKVASLLVKRTSPRNDYRPDFVGFEVP 209 Query: 185 DKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 ++FVVGYALDYN+ FRDL+H+CVI+E G+ K+ Sbjct: 210 NRFVVGYALDYNDNFRDLHHICVINEVGQKKFSV 243 >1QK4-A nrPDB Length = 233 Score = 242 bits (618), Expect = 9e-65, Method: Composition-based stats. Identities = 85/208 (40%), Positives = 126/208 (60%), Gaps = 4/208 (1%) Query: 13 DEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGY 72 D Y+ D F +P H ++++ +P GL+ DR E+LA D+ + G + +C+LKG Sbjct: 26 DNTFYNADDFLVPPHCKPYIDKILLPGGLVKDRVEKLAYDIHRTYFGEELHIICILKGSR 85 Query: 73 KFFADLLDYIKALNRNSDRSI---PMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKN 129 FF L+DY+ + + S R P ++RLKSY ND STG + V+ DDLS K+ Sbjct: 86 GFFNLLIDYLATIQKYSGRESSVPPFFEHYVRLKSYQNDNSTGQLTVLS-DDLSIFRDKH 144 Query: 130 VLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVV 189 VLIVEDI+DTG T+ ++ PK +++A+L+ KRT RS K DFVGF I D ++V Sbjct: 145 VLIVEDIVDTGFTLTEFGERLKAVGPKSMRIATLVEKRTDRSNSLKGDFVGFSIEDVWIV 204 Query: 190 GYALDYNEYFRDLNHVCVISETGKAKYK 217 G D+NE FRD +HV V+S+ + K++ Sbjct: 205 GCCYDFNEMFRDFDHVAVLSDAARKKFE 232 >5EUC-A nrPDB Length = 229 Score = 211 bits (538), Expect = 1e-55, Method: Composition-based stats. Identities = 62/203 (30%), Positives = 104/203 (51%), Gaps = 16/203 (7%) Query: 24 IPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH-------HIVALCVLKGGYKFFA 76 +P Y E E++ I R + +A+ + + G +V + VLKG + F A Sbjct: 1 MPREY-EFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTA 59 Query: 77 DLLDYIKALNRNSDRSIPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVED 135 DL + D ++P+ ++FI + SY S+G ++++ D ++ G +VLIVED Sbjct: 60 DLCRAL------CDFNVPVRMEFICVSSYGEGLTSSGQVRMLL-DTRHSIEGHHVLIVED 112 Query: 136 IIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDY 195 I+DT T+ L + P +K LL KR R V + D+V IP+ FV+GY LDY Sbjct: 113 IVDTALTLNYLYHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDY 172 Query: 196 NEYFRDLNHVCVISETGKAKYKA 218 ++ +R+L + V+ A+ +A Sbjct: 173 DDTYRELRDIVVLRPEVYAEREA 195 >3HVU-A nrPDB Length = 204 Score = 210 bits (535), Expect = 3e-55, Method: Composition-based stats. Identities = 68/195 (34%), Positives = 106/195 (54%), Gaps = 11/195 (5%) Query: 21 LFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLD 80 F +D+E+V I I ++ L + ++ +A+ VLKG F ADLL Sbjct: 19 YFQSNAMMNQDIEKVLISEEQIQEKVLELGAIIAEDYKNTVPLAIGVLKGAMPFMADLLK 78 Query: 81 YIKALNRNSDRSIPMTVDFIRLKSYCNDQ-STGDIKVIGGDDLSTLTGKNVLIVEDIIDT 139 + +DF+ + SY + STG++K++ D S + G+++LIVEDIID+ Sbjct: 79 RTDTY---------LEMDFMAVSSYGHSTVSTGEVKILKDLDTS-VEGRDILIVEDIIDS 128 Query: 140 GKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYF 199 G T+ L+ L + K VK+ +LL K T R V K D+VGF +P +FVVGY LDY E + Sbjct: 129 GLTLSYLVDLFKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQY 188 Query: 200 RDLNHVCVISETGKA 214 R+L +V V+ + + Sbjct: 189 RNLPYVGVLKPSVYS 203 >4RQB-A nrPDB Length = 186 Score = 209 bits (533), Expect = 6e-55, Method: Composition-based stats. Identities = 56/187 (29%), Positives = 103/187 (55%), Gaps = 11/187 (5%) Query: 29 AEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRN 88 DL+ V + I + + L + K+ G +V + +LKG F +DL+ I Sbjct: 9 HNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDT---- 64 Query: 89 SDRSIPMTVDFIRLKSY-CNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLL 147 +++DF+ + SY +STG++++I D S++ K+VLI+EDI++TG T++++ Sbjct: 65 -----HLSIDFMDVSSYHGGTESTGEVQIIK-DLGSSIENKDVLIIEDILETGTTLKSIT 118 Query: 148 SLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCV 207 L++ +++ +LL K R + +VG +IPD+FVVGY LDY E +R+L ++ Sbjct: 119 ELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGT 178 Query: 208 ISETGKA 214 + + Sbjct: 179 LKPEVYS 185 >4PFQ-A nrPDB Length = 207 Score = 209 bits (532), Expect = 8e-55, Method: Composition-based stats. Identities = 64/189 (33%), Positives = 98/189 (51%), Gaps = 9/189 (4%) Query: 26 NHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKAL 85 H D++RV + I DR L + + V + VL+G ADL I Sbjct: 27 THPHPDVDRVLLDEQQIRDRLAELGEQIAADYAEEPPVLVGVLRGAVMVMADLARQI--- 83 Query: 86 NRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQT 145 + + +D++ + SY + + + I D +T +NVLIVEDIID+G T++ Sbjct: 84 ------DLKVEMDWMAVSSYGSGTKSSGVVRILKDLSGDITDRNVLIVEDIIDSGLTLKW 137 Query: 146 LLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHV 205 LLS +R PK V+VA+LL K V ++GF+IP +FV+GY LDY E +R+L +V Sbjct: 138 LLSNLRSRGPKSVEVAALLRKPDAARVDIDVKYIGFDIPSEFVIGYGLDYAENYRNLPYV 197 Query: 206 CVISETGKA 214 V+S + Sbjct: 198 GVLSRSVYE 206 >6D9Q-A nrPDB Length = 183 Score = 208 bits (530), Expect = 1e-54, Method: Composition-based stats. Identities = 67/186 (36%), Positives = 105/186 (56%), Gaps = 11/186 (5%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNS 89 +D+E+V I I ++ L + ++ +A+ VLKG F ADLL Sbjct: 7 QDIEKVLISEEQIQEKVLELGAIIAEDYKNTVPLAIGVLKGAMPFMADLLKRTDTY---- 62 Query: 90 DRSIPMTVDFIRLKSYCNDQ-STGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS 148 + +DF+ + SY + STG++K++ D S + G+++LIVEDIID+G T+ L+ Sbjct: 63 -----LEMDFMAVSSYGHSTVSTGEVKILKDLDTS-VEGRDILIVEDIIDSGLTLSYLVD 116 Query: 149 LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 L + K VK+ +LL K T R V K D+VGF +P +FVVGY LDY E +R+L +V V+ Sbjct: 117 LFKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVL 176 Query: 209 SETGKA 214 + + Sbjct: 177 KPSVYS 182 >4QYI-A nrPDB Length = 186 Score = 205 bits (523), Expect = 8e-54, Method: Composition-based stats. Identities = 65/185 (35%), Positives = 106/185 (57%), Gaps = 12/185 (6%) Query: 31 DLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSD 90 +++ I + ++ + LA + ++ G IV + VLKG + F ADL+ +IK Sbjct: 7 EIKDTLISEEQLQEKVKELALQIERDFEGEEIVVIAVLKGSFVFAADLIRHIKN------ 60 Query: 91 RSIPMTVDFIRLKSYCN-DQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSL 149 +T+DFI SY N ++TG +K++ D+ +TGKNV++VEDIID+G T+ L Sbjct: 61 ---DVTIDFISASSYGNQTETTGKVKLLKDIDV-NITGKNVIVVEDIIDSGLTLHFLKDH 116 Query: 150 VRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVC-VI 208 + PK +K +LL K R V ++VGF+IPD+F+VGY +D E +R+L + V+ Sbjct: 117 FFMHKPKALKFCTLLDKPERRKVDLTAEYVGFQIPDEFIVGYGIDCAEKYRNLPFIASVV 176 Query: 209 SETGK 213 +E Sbjct: 177 TEESY 181 >1R3U-A nrPDB Length = 205 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 62/190 (32%), Positives = 100/190 (52%), Gaps = 11/190 (5%) Query: 26 NHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKAL 85 ED+E + I + + + L + ++ G +V + VLKG F + L I Sbjct: 26 PSPMEDIEEILITEEQLKAKVKELGEMITRDYEGKDLVLIGVLKGAIMFMSGLSRAI--- 82 Query: 86 NRNSDRSIPMTVDFIRLKSYCNDQST-GDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQ 144 +P+++DF+ + SY + + G +K+I D+ + GK+VLIVEDIID+G T+ Sbjct: 83 ------DLPLSIDFLAVSSYGSSTKSSGIVKIIKDHDI-DIEGKDVLIVEDIIDSGLTLA 135 Query: 145 TLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNH 204 L + P+ +K+ ++L K R K D+ GF+IPDKFVVGY LDY E +R+L Sbjct: 136 YLRETLLGRKPRSLKICTILDKPERREADVKVDYCGFKIPDKFVVGYGLDYAEKYRNLPF 195 Query: 205 VCVISETGKA 214 + V+ Sbjct: 196 IGVLKPELYK 205 >3ACB-A nrPDB Length = 181 Score = 200 bits (508), Expect = 5e-52, Method: Composition-based stats. Identities = 61/180 (33%), Positives = 98/180 (54%), Gaps = 11/180 (6%) Query: 35 VFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIP 94 V I I R E L ++ ++ G +CVL G + F ADL+ I +P Sbjct: 12 VQISAEAIKKRVEELGGEIARDYQGKTPHLICVLNGAFIFMADLVRAIP---------LP 62 Query: 95 MTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQY 153 +T+DFI + SY N +S+G+++++ L + G++V++VEDI+DTG T+ LL + Sbjct: 63 LTMDFIAISSYGNAFKSSGEVELLKDLRLP-IHGRDVIVVEDIVDTGLTLSYLLDYLEAR 121 Query: 154 NPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGK 213 P V+VA+LL K + R V ++GFEI D +V GY LD ++ R+L + I + Sbjct: 122 KPASVRVAALLSKPSRRQVEVPIHYLGFEIEDAYVYGYGLDRAQFDRNLPFITSIRPEEE 181 >1HGX-A nrPDB Length = 183 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 11/185 (5%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNS 89 +DLERV I R LA ++ + + V +CVL G F+ DLL ++ Sbjct: 8 DDLERVLYNQDDIQKRIRELAAELTEFYEDKNPVMICVLTGAVFFYTDLLKHL------- 60 Query: 90 DRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSL 149 + D+I SY +STG++ I D + + G++VL+VEDIIDTG TM LL+ Sbjct: 61 --DFQLEPDYIICSSYSGTKSTGNLT-ISKDLKTNIEGRHVLVVEDIIDTGLTMYQLLNN 117 Query: 150 VRQYNPKMVKVASLLVKRTPRSV-GYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVI 208 ++ P +KV +L K + D+ GF + +++++GY D++ +R+L + ++ Sbjct: 118 LQMRKPASLKVCTLCDKDIGKKAYDVPIDYCGFVVENRYIIGYGFDFHNKYRNLPVIGIL 177 Query: 209 SETGK 213 E+ Sbjct: 178 KESVY 182 >3OHP-A nrPDB Length = 177 Score = 197 bits (501), Expect = 3e-51, Method: Composition-based stats. Identities = 59/182 (32%), Positives = 97/182 (53%), Gaps = 12/182 (6%) Query: 34 RVFIPHGLIMDRTERLARDVMKEMGGH-HIVALCVLKGGYKFFADLLDYIKALNRNSDRS 92 V I + R L + + + G +V + +L+G + F ADL I + Sbjct: 6 EVMISEQEVAQRIRELGQQITEHYQGSSDLVLVGLLRGSFVFMADLARQIHLTH------ 59 Query: 93 IPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR 151 VDF+ SY N QS+ D++++ D + GK+VL+VEDIIDTG T+ + ++ Sbjct: 60 ---QVDFMTASSYGNSMQSSRDVRILKDLD-DDIKGKDVLLVEDIIDTGNTLNKVKEILA 115 Query: 152 QYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISET 211 PK +++ +LL K T R V + ++VGFEIPD+FVVG +DY + +R L ++ + Sbjct: 116 LREPKSIRICTLLDKPTRREVDVEVNWVGFEIPDEFVVGVGIDYAQKYRHLPYIGKVVPL 175 Query: 212 GK 213 + Sbjct: 176 AE 177 >1PZM-A nrPDB Length = 211 Score = 197 bits (500), Expect = 4e-51, Method: Composition-based stats. Identities = 52/192 (27%), Positives = 99/192 (51%), Gaps = 14/192 (7%) Query: 34 RVFIPHGLIMDRTERLARDVMKEMGGHHIV------ALCVLKGGYKFFADLLDYIKALNR 87 R + + T + A+ + + H+ LCVLKG + F ADL ++ Sbjct: 25 RTLVTQEQVWAATAKCAKKIAADYKDFHLTADNPLYLLCVLKGSFIFTADLARFL----- 79 Query: 88 NSDRSIPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTL 146 +D +P+ V+FI SY + +++G ++++ D ++ +++++VEDI+D+ T+Q L Sbjct: 80 -ADEGVPVKVEFICASSYGSGVETSGQVRMLL-DVRDSVENRHIMLVEDIVDSAITLQYL 137 Query: 147 LSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVC 206 + + P +K LL K + R V D+ IP FV+GY +D+ E +R+L +C Sbjct: 138 MRFMLAKKPASLKTVVLLDKPSGRKVDVLVDYPVITIPRAFVIGYGMDFAESYRELRDIC 197 Query: 207 VISETGKAKYKA 218 V+ + K ++ Sbjct: 198 VLKKEYYEKAES 209 >1G9T-A nrPDB Length = 182 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 59/175 (33%), Positives = 90/175 (51%), Gaps = 11/175 (6%) Query: 34 RVFIPHGLIMDRTERLARDVMKEMG--GHHIVALCVLKGGYKFFADLLDYIKALNRNSDR 91 V IP I R L R + + G +V + +L+G + F ADL ++ Sbjct: 10 EVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQ-------- 61 Query: 92 SIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR 151 + VDF+ SY + ST I D + GK+VLIVEDIID+G T+ + ++ Sbjct: 62 -VSHEVDFMTASSYGSGMSTTRDLKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILS 120 Query: 152 QYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVC 206 PK + + +LL K + R V +F+GF IPD+FVVGY +DY + +R L ++ Sbjct: 121 LREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIG 175 >4LYY-A nrPDB Length = 199 Score = 192 bits (487), Expect = 1e-49, Method: Composition-based stats. Identities = 57/179 (31%), Positives = 91/179 (50%), Gaps = 10/179 (5%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGGHH-IVALCVLKGGYKFFADLLDYIKALNRNSDR 91 V I I + + LA + ++ + +LKG F ADL IK Sbjct: 27 TEVMITAEEIDQKLDILAEQINAHYADSDRLLMVGLLKGSVVFMADLCRRIKG------- 79 Query: 92 SIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR 151 + +DF+ + SY N+ S+ I D S + G++VLIVED+ID+G T+ + ++ Sbjct: 80 --HVEIDFMSVSSYGNEMSSSRDVKILKDVQSEIQGRDVLIVEDLIDSGNTLNKVRDMLL 137 Query: 152 QYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISE 210 PK + + +LL K R V DF+GF IPD+F+VGY +DY E +R+L ++ + Sbjct: 138 LREPKSLALCTLLDKPERREVDVPVDFIGFTIPDEFIVGYGIDYAEQYRNLPYIAKVVP 196 >4QRI-A nrPDB Length = 207 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 55/182 (30%), Positives = 103/182 (56%), Gaps = 11/182 (6%) Query: 37 IPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMT 96 I + + LA + ++ + + +CVLKGG FF DL I + Sbjct: 37 FSREDISQKVKSLALQISEDYKKLNPIFICVLKGGVYFFTDLTREIP---------FSVE 87 Query: 97 VDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPK 156 ++F++ +SY STG I+++ D+ L+ ++V+IVEDI+DTG T+Q L+ + NP Sbjct: 88 INFVQARSYSGTVSTGKIELLKDIDI-DLSDRHVIIVEDILDTGFTLQYLVRHIFTRNPA 146 Query: 157 MVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKY 216 +++ +LL+K ++ + ++G+ IPD+F+VGY LD++ +R+L + V+ E G+ ++ Sbjct: 147 SLEIVTLLLKERKDTLEFPVKYIGWRIPDEFLVGYGLDFDGRYRNLPDIHVL-EPGEPQF 205 Query: 217 KA 218 Sbjct: 206 PV 207 >6AQO-A nrPDB Length = 272 Score = 189 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 68/232 (29%), Positives = 110/232 (47%), Gaps = 29/232 (12%) Query: 10 ISDDEPGYDLD-LFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMG---------- 58 + + G D D + E V I + +A+ + Sbjct: 45 LKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNK 104 Query: 59 ----------GHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCND 108 + ++ + VLKG Y F AD++ Y+ D +P VDFIR+ SY Sbjct: 105 GNSALAPITDENPLIIISVLKGSYIFTADMVRYL------GDCGLPNVVDFIRITSYRGT 158 Query: 109 -QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR-QYNPKMVKVASLLVK 166 +S+G ++V+ + LTGK+VLI+EDI DTG+TM+ L+ +R +Y P +KV L+ K Sbjct: 159 TKSSGTVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDK 218 Query: 167 RTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 218 R V +KP+FV P ++VVGY + N+ +R+ HV V+ +Y + Sbjct: 219 PGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPS 270 >6APT-A nrPDB Length = 216 Score = 184 bits (467), Expect = 2e-47, Method: Composition-based stats. Identities = 51/202 (25%), Positives = 100/202 (49%), Gaps = 15/202 (7%) Query: 23 CIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGG-------HHIVALCVLKGGYKFF 75 P + V + R +A+ + + + +V + VLKG + F Sbjct: 7 MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFT 66 Query: 76 ADLLDYIKALNRNSDRSIPMTVDFIRLKSYCND-QSTGDIKVIGGDDLSTLTGKNVLIVE 134 AD++ + D +P V+F+R SY +D +S G + V D L + GK+VL++E Sbjct: 67 ADMVRIL------GDFGVPTRVEFLRASSYGHDTKSCGRVDV-KADGLCDIRGKHVLVLE 119 Query: 135 DIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALD 194 DI+DT T++ ++ +++ P +K + K R + + ++V ++P+ FVVGY LD Sbjct: 120 DILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLD 179 Query: 195 YNEYFRDLNHVCVISETGKAKY 216 Y++ +R++ V ++ + + Sbjct: 180 YDQSYREVRDVVILKPSVYETW 201 >5KNP-A nrPDB Length = 207 Score = 179 bits (455), Expect = 7e-46, Method: Composition-based stats. Identities = 56/193 (29%), Positives = 93/193 (48%), Gaps = 15/193 (7%) Query: 28 YAEDLERVFIPHGLIMDRTERLARDVMKEMG------GHHIVALCVLKGGYKFFADLLDY 81 Y D++ V + I R L + + G ++ + VLKG F DL Sbjct: 24 YPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARA 83 Query: 82 IKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGK 141 I +P +F+ + SY + S+ + I D + G++VLIVED++D+G Sbjct: 84 IP---------VPTQFEFMAVSSYGSSTSSSGVVRILKDLDRDIHGRDVLIVEDVVDSGL 134 Query: 142 TMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRD 201 T+ L + NP+ ++V +LL K + +VGF+IP+ FVVGY LDY+E +RD Sbjct: 135 TLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRD 194 Query: 202 LNHVCVISETGKA 214 L+++ + Sbjct: 195 LSYIGTLDPRVYQ 207 >5ESX-A nrPDB Length = 195 Score = 163 bits (414), Expect = 4e-41, Method: Composition-based stats. Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%) Query: 36 FIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPM 95 + +R+A + + + + V +CV+ GG +LL + P+ Sbjct: 23 LYTSNEVEAALDRMAIKIHETLQDKNPVIICVMVGGLVPLGNLLHRL---------DFPL 73 Query: 96 TVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNP 155 VD++ Y D + GDI + S L G+ VL+V+DI+D G T+ +++ ++ Sbjct: 74 EVDYVHATRYRGDLTGGDI-LWKVRPSSNLAGRTVLVVDDILDGGITLAAIINEIKAMGA 132 Query: 156 KMVKVASLLVKRTPRSVG--YKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGK 213 V A L+ K R K DFVG ++ D ++ GY +DY+EY R+ + ++ + Sbjct: 133 AEVYSAVLVDKYRKRVPNGLQKADFVGLQVEDHYIFGYGMDYHEYLRNAPGIFIVHPDHE 192 Query: 214 A 214 A Sbjct: 193 A 193 >5BQP-A nrPDB Length = 179 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 43/172 (25%), Positives = 77/172 (44%), Gaps = 16/172 (9%) Query: 40 GLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDF 99 I D + ++K V + VL GG SD + + Sbjct: 10 DEIEDAVFSIGEALVKS-NYIPDVLIAVLTGGIIPA----------KLLSDLLDLKVIRY 58 Query: 100 IRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVK 159 I +K Y + T VI +L GK VL+V+D+ DTG+T++ + +++ +NP V Sbjct: 59 IDIKFYRSVGKTESKPVIRSVYTDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVM 118 Query: 160 VASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISET 211 A+L +K + + PDF +I DK+++ + D + R+ ++V V + Sbjct: 119 TAALYLKPWSKRI---PDFYYKQI-DKWII-FPWDKWDVVRENSNVPVDKKE 165 >4P86-A nrPDB Length = 183 Score = 101 bits (252), Expect = 3e-22, Method: Composition-based stats. Identities = 36/158 (22%), Positives = 79/158 (50%), Gaps = 12/158 (7%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGG-HHIVALCVLKGGYKFFADLLDYIKALNRNSDR 91 + V + I R+A ++++ G ++ + + + G L + I+ + N Sbjct: 5 KAVILDEQAIRRALTRIAHEMIERNKGMNNCILVGIKTRGIYLAKRLAERIEQIEGN--- 61 Query: 92 SIPMTVDFIRLKSYCND---QSTGDIKVIGGDDLS-TLTGKNVLIVEDIIDTGKTMQTLL 147 P+TV I + Y +D +++ D ++ G D+ +T + V++V+D++ TG+T++ + Sbjct: 62 --PVTVGEIDITLYRDDLSKKTSNDEPLVKGADIPVDITDQKVILVDDVLYTGRTVRAGM 119 Query: 148 S-LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 LV P +++A L+ R R + + D++G IP Sbjct: 120 DALVDVGRPSSIQLAVLVD-RGHRELPIRADYIGKNIP 156 >4P80-A nrPDB Length = 180 Score = 97.3 bits (241), Expect = 5e-21, Method: Composition-based stats. Identities = 33/157 (21%), Positives = 77/157 (49%), Gaps = 11/157 (7%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGG-HHIVALCVLKGGYKFFADLLDYIKALNRNSDR 91 + V + I R+A ++++ G ++ + + + G L + I+ + N Sbjct: 5 KAVVLDEQAIRRALTRIAHEMIERNKGMNNCILVGIKTRGIYLAKRLAERIEQIEGNK-- 62 Query: 92 SIPMTVDFIRLKSYCND--QSTGDIKVIGGDDLS-TLTGKNVLIVEDIIDTGKTMQTLLS 148 +TV + + Y +D +++ ++ G D+ +T + V++V+D++ TG+T++ + Sbjct: 63 ---VTVGELDITLYRDDLTKTSNKEPLVKGADIPVDITDQKVILVDDVLYTGRTVRAAMD 119 Query: 149 -LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 LV P +++A L+ R R + + D++G IP Sbjct: 120 ALVDVGRPSSIQLAVLVD-RGHRELPIRADYIGKNIP 155 >1VDM-A nrPDB Length = 153 Score = 96.2 bits (238), Expect = 9e-21, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 69/158 (43%), Gaps = 17/158 (10%) Query: 32 LERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDR 91 +++V++ + LA + + V + V +GG L + Sbjct: 1 MDKVYLTWWQVDRAIFALAEKLRE---YKPDVIIGVARGGLIPAVRLSHILG-------- 49 Query: 92 SIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVR 151 IP+ V I +K Y G+ VI L K V+IV+D+ DTGKT++ ++ V+ Sbjct: 50 DIPLKV--IDVKFYKGIDERGEKPVITIPIHGDLKDKRVVIVDDVSDTGKTLEVVIEEVK 107 Query: 152 QYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVV 189 + K +K+A L +K V PD+ F K++V Sbjct: 108 KLGAKEIKIACLAMKPWTSVV---PDYYVFRTE-KWIV 141 >4P3K-A nrPDB Length = 180 Score = 96.2 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 74/157 (47%), Gaps = 11/157 (7%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGG-HHIVALCVLKGGYKFFADLLDYIKALNRNSDR 91 + V + I R+A ++++ G + V + + G L + I+ + Sbjct: 5 KAVVLDEQAIRRALTRIAHEIIERNKGVDNCVLVGIKTRGIYLAKRLAERIEQIEGK--- 61 Query: 92 SIPMTVDFIRLKSYCND--QSTGDIKVIGGDDLS-TLTGKNVLIVEDIIDTGKTMQTLLS 148 P+ V I + Y +D ++ ++ G D+ +T K V++V+D++ TG+T++ + Sbjct: 62 --PVPVGEIDITLYRDDLTVTSNKEPLVKGTDIPVDITDKKVILVDDVLYTGRTVRAGMD 119 Query: 149 -LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 L+ P +++A L+ R R + + D+VG +P Sbjct: 120 ALMDLGRPSQIQLAVLVD-RGHRELPIRADYVGKNVP 155 >4P83-A nrPDB Length = 182 Score = 87.7 bits (216), Expect = 4e-18, Method: Composition-based stats. Identities = 34/158 (21%), Positives = 75/158 (47%), Gaps = 12/158 (7%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGGHH-IVALCVLKGGYKFFADLLDYIKALNRNSDR 91 + V + I R+A ++++ G V + + G L + I+ + Sbjct: 5 KAVIMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGA--- 61 Query: 92 SIPMTVDFIRLKSYCND---QSTGDIKVIGGDDLS-TLTGKNVLIVEDIIDTGKTMQTLL 147 P+ V I + Y +D ++ D ++ G ++ +T +NV++V+D++ TG+T++ + Sbjct: 62 --PVPVGEIDITLYRDDLSVKTDDDEPLVKGTNVPFPVTERNVILVDDVLFTGRTVRAGM 119 Query: 148 S-LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 ++ P +++A L+ R R + + DFVG +P Sbjct: 120 DAVMDLGRPARIQLAVLVD-RGHRELPIRADFVGKNVP 156 >1XZN-A nrPDB Length = 179 Score = 82.7 bits (203), Expect = 1e-16, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 74/158 (46%), Gaps = 12/158 (7%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGGHH-IVALCVLKGGYKFFADLLDYIKALNRNSDR 91 + V + I R+A ++++ G V + + G L + I+ + S Sbjct: 3 KAVVMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGAS-- 60 Query: 92 SIPMTVDFIRLKSYCND---QSTGDIKVIGGDDLS-TLTGKNVLIVEDIIDTGKTMQTLL 147 + V + + Y +D ++ ++ G ++ +T +NV++V+D++ TG+T++ + Sbjct: 61 ---VPVGELDITLYRDDLTVKTDDHEPLVKGTNVPFPVTERNVILVDDVLFTGRTVRAAM 117 Query: 148 S-LVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 ++ P +++A L+ R R + + DFVG +P Sbjct: 118 DAVMDLGRPARIQLAVLVD-RGHRELPIRADFVGKNVP 154 >1UFR-A nrPDB Length = 181 Score = 78.5 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 10/153 (6%) Query: 36 FIPHGLIMDRTERLARDVMKEMGGHH-IVALCVLKGGYKFFADLLDYIKALNRNSDRSIP 94 + + R+A ++++ G + + + G + +I + +P Sbjct: 7 LMNAPEMRRALYRIAHEIVEANKGTEGLALVGIHTRGIPLAHRIARFIAEFE---GKEVP 63 Query: 95 MTVDFIRLKSYCNDQS--TGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS-LVR 151 + V + + Y +D + +V LTGK +++V+D++ TG+T + L L+ Sbjct: 64 VGV--LDITLYRDDLTEIGYRPQVRETRIPFDLTGKAIVLVDDVLYTGRTARAALDALID 121 Query: 152 QYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 P+ + +A L+ R R + + DFVG +P Sbjct: 122 LGRPRRIYLAVLVD-RGHRELPIRADFVGKNVP 153 >5IAO-A nrPDB Length = 199 Score = 61.5 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 63/162 (38%), Gaps = 17/162 (10%) Query: 34 RVFIPHGLIMDRTERLARDVMKEMGGHHIV--------ALCVLKGGYKFFADLLDYIKAL 85 R + + R+A ++++ V L + G L I Sbjct: 14 RELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRVVLLGIPTRGVTLANRLAGNITEY 73 Query: 86 NRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLST--LTGKNVLIVEDIIDTGKTM 143 + I + + + Y +D + + + + V++V+D++ +G+++ Sbjct: 74 S-----GIHVGHGALDITLYRDDLMIKPPRPLASTSIPAGGIDDALVILVDDVLYSGRSV 128 Query: 144 QTLLSLV-RQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIP 184 ++ L + P+ V++A L+ R R + + D+VG +P Sbjct: 129 RSALDALRDVGRPRAVQLAVLVD-RGHRELPLRADYVGKNVP 169 >1DQP-A nrPDB Length = 230 Score = 61.1 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 74/185 (40%), Gaps = 26/185 (14%) Query: 35 VFIPHGLIMDRTERLARDVMKEMGG--HHIVALCVLKGGYKFFADLLDYIKALNRNSDRS 92 + AR + + + + +L G Y + + L ++ Sbjct: 34 LLATFEECKALAADTARRMNEYYKDVAEPVTLVALLTGAYLYASLLTVHLT--------- 84 Query: 93 IPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKN-VLIVEDIIDTGKTMQTLLSLVR 151 P T+ F+++ SY + + V +DL L K V+++++ +D+G T+ ++ + Sbjct: 85 FPYTLHFVKVSSYKG--TRQESVVFDEEDLKQLKEKREVVLIDEYVDSGHTIFSIQEQI- 141 Query: 152 QYNPKMVKVASLLVKRTP--RSVGYKPD---FVGFE-IPD-KFVVGYALDYNEYFRDLNH 204 K K+ S VK + D F G+ +P +++G+ LD N R H Sbjct: 142 ----KHAKICSCFVKDVDAIKKHSALADTKMFYGYTPMPKGSWLIGFGLDDNGLRRGWAH 197 Query: 205 VCVIS 209 + I+ Sbjct: 198 LFDIN 202 >6FSP-A nrPDB Length = 174 Score = 58.8 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 110 STGDIK--VIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKR 167 +TG + V+ G D+ + GK V IV+D++ TG T+ L L+ ++V V ++ + Sbjct: 100 TTGKPQLLVLDGADIPRVRGKKVAIVDDVVSTGSTLAGLRELIESVGGEVVAVLAVFTEG 159 Query: 168 TPRS 171 TPR Sbjct: 160 TPRQ 163 >4TS7-A nrPDB Length = 210 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 65/164 (39%), Gaps = 16/164 (9%) Query: 36 FIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPM 95 + I+ + +LA + + + V + + +GG + D + + S Sbjct: 8 VVTWDEIVSLSTKLAEKIKADEYNVN-VIVAIARGGLVPARLVADVLGVFDILS------ 60 Query: 96 TVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLV-RQYN 154 I+++ + S + L+ KNVLI++DI DTG +++ V + Sbjct: 61 ----IKIEHWIETASHTPEAKVKYPFKVDLSDKNVLIIDDITDTGDSIELARKYVMENFR 116 Query: 155 PKMVKVASL-LVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNE 197 P VK A+L +K + PD+ EI Y +Y E Sbjct: 117 PTEVKTATLQYIKPAAK---IIPDYYAEEIVSWAWFMYPWNYWE 157 >5XTK-A nrPDB Length = 152 Score = 53.0 bits (126), Expect = 9e-08, Method: Composition-based stats. Identities = 32/167 (19%), Positives = 64/167 (38%), Gaps = 24/167 (14%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRS 92 E+ + ++ +LA+ ++ I+A+ +GG L + Sbjct: 3 EKYVVTWDMLQIHARKLAQRLLPAEQWKGIIAVS--RGGLVPAGILARELGIRY------ 54 Query: 93 IPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQ 152 VD + + SY +D D+KV+ + G+ ++++D++DTG T + + Sbjct: 55 ----VDTVCISSYDHDNQR-DLKVLKRAEGD---GEGFIVIDDLVDTGGTATAIREMY-- 104 Query: 153 YNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYF 199 PK ++ K R D+V +IP + D F Sbjct: 105 --PKA-HFVTIFAKPAGR--PLVDDYVV-DIPQNTWIEQPWDMAVTF 145 >4JLS-A nrPDB Length = 152 Score = 53.0 bits (126), Expect = 9e-08, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 64/162 (39%), Gaps = 24/162 (14%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRS 92 E+ + ++ +LA +M I+A+ +GG A L + + Sbjct: 3 EKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVS--RGGLVPGALLARELGIRH------ 54 Query: 93 IPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQ 152 VD + + SY +D ++KV+ + G+ ++++D++DTG T + + Sbjct: 55 ----VDTVCISSYDHDNQR-ELKVLKRAEGD---GEGFIVIDDLVDTGGTAVAIREMY-- 104 Query: 153 YNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALD 194 PK ++ K R D+V +IP + D Sbjct: 105 --PKA-HFVTIFAKPAGR--PLVDDYVV-DIPQDTWIEQPWD 140 >5VOG-A nrPDB Length = 183 Score = 48.0 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 63/165 (38%), Gaps = 11/165 (6%) Query: 33 ERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRS 92 ++++ + I + LA + + G + + + GG+ A +L + + Sbjct: 11 QKIWYTYDDIHRVIKALAEKI-RNAGVKYDAMIAIGGGGFIP-ARMLRCFLEIPIYA--- 65 Query: 93 IPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQ 152 +T + + L GKNVL+V+++ D+ TM+ L + + Sbjct: 66 --VTTAYYDSDNEGQVTEEVKKVQWLDPVPEVLRGKNVLVVDEVDDSRVTMEFCLKELLK 123 Query: 153 YNPKMVKVASLLVKRTPRSVGYK---PDFVGFEIPDKFVVGYALD 194 + V VA L K ++ P F G + D ++ Y D Sbjct: 124 EDFDTVGVAVLHEKIKAKAGKIPEGIPYFSGITVEDWWI-NYPWD 167 >4TWB-A nrPDB Length = 291 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 108 DQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL 163 D++TG+++ I L GK+V+I++DII TG T+ L K V A++ Sbjct: 191 DRTTGEVR-IKEAPNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAI 245 >1ZN9-A nrPDB Length = 180 Score = 43.4 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 51/149 (34%), Gaps = 12/149 (8%) Query: 21 LFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLD 80 F P D+ V LAR + GG + G+ F L Sbjct: 18 DFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQ 77 Query: 81 YIKA----LNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDI 136 + + + P SY + ++++ G+ V++V+D+ Sbjct: 78 ELGLGCVLIRKRGKLPGPTLW-----ASYSLEYGKAELEIQKDALEP---GQRVVVVDDL 129 Query: 137 IDTGKTMQTLLSLVRQYNPKMVKVASLLV 165 + TG TM L+ + ++++ SL+ Sbjct: 130 LATGGTMNAACELLGRLQAEVLECVSLVE 158 >2XBU-A nrPDB Length = 221 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 36/96 (37%), Gaps = 26/96 (27%) Query: 124 TLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVK-----------------VASLLVK 166 L GKNVLIV+++ DT T+ LS + + + K + L K Sbjct: 100 DLVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKAKGIDTEKSPEMKTNFGIFVLHDK 159 Query: 167 RTPRSVGYKPD--------FVGFEIPDKFVVGYALD 194 + P+ + F +PDK+ Y + Sbjct: 160 QKPKKADLPAEMLNDKNRYFAAKTVPDKW-YAYPWE 194 >2E55-A nrPDB Length = 208 Score = 41.1 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 49/143 (34%), Gaps = 17/143 (11%) Query: 29 AEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRN 88 E L+ + + + + IV + +L+ G F L + Sbjct: 40 YEALKDILLEEKEVRTWI---GNKRFNYLNEEEIVFVPILRAGLSFLEGALQVVPNA--- 93 Query: 89 SDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS 148 V F+ +K + I L L GK V+I++ ++ TG T++ L Sbjct: 94 -------KVGFLGIKRNEETLESH----IYYSRLPELKGKIVVILDPMLATGGTLEVALR 142 Query: 149 LVRQYNPKMVKVASLLVKRTPRS 171 + +++P VK + Sbjct: 143 EILKHSPLKVKSVHAIAAPEGLK 165 >5MP7-A nrPDB Length = 326 Score = 39.9 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 48/132 (36%), Gaps = 27/132 (20%) Query: 49 LARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKA-----LNRNSDRSIPMTVDFIRLK 103 L + + +V + G + D + +++ D +P V Sbjct: 159 LTGYIGEHYADEDMVVVSPDSGRVRVAEKWADSLGGVPLAFIHKTRDPLVPNQVK----- 213 Query: 104 SYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVAS- 162 + + GK ++ +D+IDTG T+ ++L+R+ K V +A+ Sbjct: 214 --------------SNRVVGDVKGKTCILTDDMIDTGGTIAGAVNLLREDGAKDVIIAAT 259 Query: 163 --LLVKRTPRSV 172 +L P+ + Sbjct: 260 HGVLSDPAPQRL 271 >1U9Y-A nrPDB Length = 284 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 124 TLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL 163 ++V IV+DII TG TM T + L+++ K + A + Sbjct: 202 DAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241 >1ECF-A nrPDB Length = 504 Score = 39.2 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 21/144 (14%), Positives = 52/144 (36%), Gaps = 8/144 (5%) Query: 22 FCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHI-VALCVLKGGYKFFADLLD 80 + ++++ + + + +L + +E I V + + + D+ Sbjct: 256 YVYFARPDSFIDKISVYSARV-NMGTKLGEKIAREWEDLDIDVVIPIPETS----CDIAL 310 Query: 81 YIKALNRNSDRSIPMTVDFIRLKSY--CNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIID 138 I + R + ++ ++ + + KNVL+V+D I Sbjct: 311 EIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIV 370 Query: 139 TGKTMQTLLSLVRQYNPKMVKVAS 162 G T + ++ + R+ K V +AS Sbjct: 371 RGTTSEQIIEMAREAGAKKVYLAS 394 >4S2U-A nrPDB Length = 316 Score = 38.8 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 22/37 (59%) Query: 122 LSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMV 158 + + G++ ++V+D+IDTG T+ +++ K V Sbjct: 209 IGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 245 >1I5E-A nrPDB Length = 209 Score = 38.0 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 42/119 (35%), Gaps = 13/119 (10%) Query: 54 MKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGD 113 K + G + + +L+ G +L I A + Y + Q+ Sbjct: 64 AKVIAGKKLGVIPILRAGIGMVDGILKLIPAAKVG------------HIGLYRDPQTLKP 111 Query: 114 IKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSV 172 ++ S + ++ +IV+ ++ TG + + +++ K +K L+ Sbjct: 112 VEYY-VKLPSDVEERDFIIVDPMLATGGSAVAAIDALKKRGAKSIKFMCLIAAPEGVKA 169 >6NFE-A nrPDB Length = 323 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 41/111 (36%), Gaps = 17/111 (15%) Query: 49 LARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCND 108 L D+ K ++I+ + GG + + + I K Sbjct: 160 LLEDITK-QKLNNIMIVSPDVGGVVRARAVAKRLNDAELS-----------IIDKRRSGP 207 Query: 109 QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVK 159 + + +IG KN +IV+DI+DT T+ T +++ K V+ Sbjct: 208 NKSEVMHIIGEP-----ANKNCIIVDDIVDTAGTLCTAAHELKKNGAKSVR 253 >3NAG-A nrPDB Length = 286 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 24/40 (60%) Query: 124 TLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL 163 + GK +LIV+DII TG T+ L+R+ + V+++ Sbjct: 200 DVNGKKLLIVDDIISTGGTIAKSSGLLREKGASKIYVSAV 239 >1DKU-A nrPDB Length = 317 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 40/120 (33%), Gaps = 25/120 (20%) Query: 49 LARDVMKEMGG----HHIVALCVLKGGYKFFADLLDYIKALNRNSD--RSIPMTVDFIRL 102 + ++ E IV + GG L D +KA D R P + + + Sbjct: 152 MGVPILGEYFEGKNLEDIVIVSPDHGGVTRARKLADRLKAPIAIIDKRRPRPNVAEVMNI 211 Query: 103 KSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVAS 162 + + GK ++++DIIDT T+ + + + K V Sbjct: 212 -------------------VGNIEGKTAILIDDIIDTAGTITLAANALVENGAKEVYACC 252 >5HKF-A nrPDB Length = 189 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 31/55 (56%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPD 177 S +TG+ VL+VED TG + T + V+ ++V VA+++ + T + + + Sbjct: 119 SEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAIEAE 173 >2EHJ-A nrPDB Length = 208 Score = 37.2 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 44/112 (39%), Gaps = 13/112 (11%) Query: 58 GGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVI 117 G I + +L+ G +L+ + + + + Y N+++ + Sbjct: 67 KGKKITVVPILRAGLGMMDGVLENVPSARISV------------VGMYRNEETLEPVPYF 114 Query: 118 GGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTP 169 +S + + LIV+ ++ TG ++ + L+++ +KV L+ Sbjct: 115 QK-LVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEG 165 >1P4A-A nrPDB Length = 285 Score = 36.8 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 31/58 (53%) Query: 108 DQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLV 165 S+ I+ + S TG NVLI++D + G T+ +++L+ ++N + + L+ Sbjct: 177 SGSSNRIQTMSLAKRSMKTGSNVLIIDDFMKAGGTINGMINLLDEFNANVAGIGVLVE 234 >3QW4-B nrPDB Length = 453 Score = 36.5 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 23/47 (48%) Query: 126 TGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSV 172 G V+I++D++ TG+T + +R ++V + L+ + Sbjct: 364 KGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDRDMGAKA 410 >4M0K-A nrPDB Length = 199 Score = 36.1 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 58/162 (35%), Gaps = 16/162 (9%) Query: 21 LFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIV-ALCVLKGGYKFFADLL 79 F P +D+ V L+ E L ++ I + + G+ L Sbjct: 40 DFPEPGIQFKDITPVLGHPELLRLAIEAL----LEPFQEQEITKVVGIESRGFILGGMLA 95 Query: 80 DYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDT 139 ++ A + + + +SY + T I++ G VLI +D+I T Sbjct: 96 HHLDAGFVPVRKKGKLPYQTL-AESYQLEYGTDTIEMHIDAIEP---GDRVLIHDDVIAT 151 Query: 140 GKTMQTLLSLVRQYNPKMVKVASLL-------VKRTPRSVGY 174 G T + + LV + ++V A L+ KR P V Sbjct: 152 GGTAEATIRLVERAGGEVVGCAFLIELTGLQGRKRLPAHVPV 193 >2P1Z-A nrPDB Length = 180 Score = 36.1 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 29/55 (52%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPD 177 + GK VL+VED TG + T + +R+ ++V VA+++ + T + + Sbjct: 110 PDVVGKKVLVVEDTTTTGNSPLTAVKALREAGAEVVGVATVVDRATGAADVIAAE 164 >1WD5-A nrPDB Length = 208 Score = 35.7 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 126 TGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTP-RSVGYKPDFVGFEIP 184 G++V++V+D + TG +M+ LS+V Q P+ V VA + + + + V +P Sbjct: 119 KGRDVVLVDDGVATGASMEAALSVVFQEGPRRVVVAVPVASPEAVERLKARAEVVALSVP 178 Query: 185 DKF--VVGYALDYNE 197 F V Y LD+ E Sbjct: 179 QDFAAVGAYYLDFGE 193 >3DAH-A nrPDB Length = 319 Score = 34.5 bits (78), Expect = 0.040, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 21/37 (56%) Query: 122 LSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMV 158 + + G+ +I++D++DT T+ ++++ K V Sbjct: 211 IGEVEGRTCVIMDDMVDTAGTLCKAAQVLKERGAKQV 247 >3G6W-A nrPDB Length = 216 Score = 34.2 bits (77), Expect = 0.045, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 42/107 (39%), Gaps = 9/107 (8%) Query: 60 HHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGG 119 ++IV + +L+ LL + + + VD + I Sbjct: 71 NNIVIINILRAAVPLVEGLLKAFPKARQGVIGASRVEVD-------GKEVPKDMDVYIYY 123 Query: 120 DDLSTLTGK--NVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 + + K NV+I + +I T TM +L V + NPK + + S++ Sbjct: 124 KKIPDIRAKVDNVIIADPMIATASTMLKVLEEVVKANPKRIYIVSII 170 >5T3O-A nrPDB Length = 307 Score = 32.6 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 30/165 (18%), Positives = 50/165 (30%), Gaps = 31/165 (18%) Query: 21 LFCIPNHYAEDLERVFIPHGLIMDRTERLARD-----------------VMKEMGGHHIV 63 F +D R+ I LI D + D + + V Sbjct: 89 YFSYARSDKKDAPRISITARLIADLLQTAGADRVLTMTLHSPQVHGFFKIPVDHLSAEPV 148 Query: 64 ALCV------LKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVI 117 L+ D D +A +P+ FI S +++V Sbjct: 149 IANYFATRVDLENAVVVAPDAGDLKRASALARRLGLPLA--FID----KERVSDTEVRV- 201 Query: 118 GGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVAS 162 + + GK LIV+D I T ++ + + Q K V A+ Sbjct: 202 -RMLVGEVEGKTALIVDDEISTAGSLVEAVEALMQAGAKEVYAAA 245 >1VCH-A nrPDB Length = 175 Score = 32.6 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 30/58 (51%) Query: 112 GDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTP 169 G++ + L + V++V D++ +G+TM+ + +V + +V ++ + TP Sbjct: 105 GEVLWLDRRFAEKLLNQRVVLVSDVVASGETMRAMEKMVLRAGGHVVARLAVFRQGTP 162 >4MB6-A nrPDB Length = 187 Score = 32.2 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Query: 104 SYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL 163 SY + T +++ G VL+V+D++ TG T++ + L+R+ ++V A + Sbjct: 103 SYELEYGTDTLEIHTDSIQP---GDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFI 159 Query: 164 LVKRT 168 + Sbjct: 160 INLPE 164 >1AO0-A nrPDB Length = 459 Score = 31.5 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 25/47 (53%) Query: 114 IKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKV 160 +++ + GK V++V+D I G T + +++++R+ V V Sbjct: 325 VRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHV 371 >4RV4-A nrPDB Length = 234 Score = 30.7 bits (68), Expect = 0.44, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 24/40 (60%) Query: 126 TGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLV 165 G+ V++VED+I TG + T + +R+ +++ + S+ Sbjct: 136 KGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFT 175 >5ZYW-A nrPDB Length = 254 Score = 30.3 bits (67), Expect = 0.72, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 16/39 (41%) Query: 11 SDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERL 49 D Y ++F + E LE + P + +R E L Sbjct: 72 EDGFKEYTSNVFLQGKRFHEALESILSPQETLKERDENL 110 >5ZYT-A nrPDB Length = 324 Score = 30.3 bits (67), Expect = 0.72, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 16/39 (41%) Query: 11 SDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERL 49 D Y ++F + E LE + P + +R E L Sbjct: 142 EDGFKEYTSNVFLQGKRFHEALESILSPQETLKERDENL 180 >2FXV-A nrPDB Length = 194 Score = 29.9 bits (66), Expect = 0.78, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 75 FADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVE 134 L + + +S+ +T + + Y + T + G LS +VLI++ Sbjct: 67 MTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQD--HVLIID 124 Query: 135 DIIDTGKTMQTLLSLVRQYNPKMVKVASLLVK 166 D + G+ L+S+V+Q + + ++ K Sbjct: 125 DFLANGQAAHGLVSIVKQAGASIAGIGIVIEK 156 >4LZA-A nrPDB Length = 195 Score = 29.9 bits (66), Expect = 0.84, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 125 LTGKNVLIVEDIIDTGKTMQTLLSLVRQYN 154 L G+ V+IV+D++ TG T+ LV Sbjct: 134 LEGQRVVIVDDLLATGGTIYASAKLVESLG 163 >4AXH-A nrPDB Length = 668 Score = 29.9 bits (66), Expect = 0.86, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 27/52 (51%) Query: 113 DIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLL 164 ++ + +++ + G + L++ D + T +T + L L Q+ PK VA + Sbjct: 126 QVRGLDPANMTIIEGDSGLVLIDTLTTAETARAALDLYFQHRPKKPIVAVVY 177 >5Z0Y-A nrPDB Length = 470 Score = 29.9 bits (66), Expect = 0.90, Method: Composition-based stats. Identities = 6/42 (14%), Positives = 18/42 (42%) Query: 26 NHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCV 67 + + E+V + + +RL ++ + H+V + + Sbjct: 314 PEFKQYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSL 355 >2DY0-A nrPDB Length = 190 Score = 29.9 bits (66), Expect = 0.95, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 7/52 (13%) Query: 105 YCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPK 156 Y DQ + I D VL+V+D++ TG T++ + L+R+ + Sbjct: 111 YGTDQLEIHVDAIKPGD-------KVLVVDDLLATGGTIEATVKLIRRLGGE 155 >3N2L-A nrPDB Length = 238 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 24/54 (44%), Gaps = 1/54 (1%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKP 176 S L G+ V++V+D+I G ++ + L++ + V + ++ Sbjct: 139 SKLEGR-VMLVDDVITAGTAIRESMELIQANKADLAGVLVAIDRQEKGKGELSA 191 >1O5O-A nrPDB Length = 221 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 12/122 (9%), Positives = 43/122 (35%), Gaps = 13/122 (10%) Query: 51 RDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQS 110 + + + IV + +L+ G +L+ + + + Y + ++ Sbjct: 73 KTIGYRINDKDIVVVPILRAGLVMADGILELLPNASVG------------HIGIYRDPET 120 Query: 111 TGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPR 170 ++ K V +++ ++ TG + + ++++ K + + +L+ Sbjct: 121 LQAVEYYAKLPPLN-DDKEVFLLDPMLATGVSSIKAIEILKENGAKKITLVALIAAPEGV 179 Query: 171 SV 172 Sbjct: 180 EA 181 >2WNS-A nrPDB Length = 205 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 89 SDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLS 148 S IPM + K Y G +++ G G+ LI+ED++ +G ++ + Sbjct: 82 STNQIPMLIRRKETKDY------GTKRLVEGTINP---GETCLIIEDVVTSGSSVLETVE 132 Query: 149 LVRQYNPKMVKVASLLVKRTPRSVGYKPD 177 ++++ K+ LL + + Sbjct: 133 VLQKEGLKVTDAIVLLDREQGGKDKLQAH 161 >1OPR-A nrPDB Length = 213 Score = 29.1 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKP 176 S L G+ V++V+D+I G ++ + +++ + + V L ++ Sbjct: 114 SALQGR-VMLVDDVITAGTAIRESMEIIQAHGATLAGVLISLDRQERGRGEISA 166 >4G5H-A nrPDB Length = 363 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 105 YCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKM 157 Y N TG+ K+ + ++ ++L VE+I + T++ + + + Y M Sbjct: 311 YSNYVETGNEKITQSYEYNS-DNTHILTVEEIKEKLLTLEYVRNELNDYKASM 362 >4WN3-A nrPDB Length = 232 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 23/53 (43%) Query: 123 STLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYK 175 S L K +LI++D++ G + ++ ++V L ++ S K Sbjct: 121 SALENKRILIIDDVMTAGTAINEAFEIISNAKGQVVGSIIALDRQEVVSTDDK 173 >2YCL-A nrPDB Length = 445 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 23/57 (40%) Query: 37 IPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSI 93 + G I +R E++ + V +G H V L LKG + A + +D Sbjct: 102 LSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPF 158 >4PAW-A nrPDB Length = 225 Score = 28.8 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 45/120 (37%), Gaps = 23/120 (19%) Query: 47 ERLARDVMKEMGGHHIVALCVLK---GGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLK 103 E+LA ++ K++ H+ CV GG +L + V FI + Sbjct: 65 EQLALELAKQIQEAHLNIECVCSPAIGGILAGYELARALG-------------VRFIFTE 111 Query: 104 SYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL 163 N + + + +L+ EDII TGK+ ++ + ++V +L Sbjct: 112 RVDNTMALRRGFEVK-------KNEKILVCEDIITTGKSAMECAKVLEEKGAQIVAFGAL 164 >5YW2-A nrPDB Length = 179 Score = 28.8 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 17/27 (62%) Query: 130 VLIVEDIIDTGKTMQTLLSLVRQYNPK 156 VL+V+D++ TG T + + L+ + K Sbjct: 123 VLVVDDLLATGGTAKATVDLIEKTQAK 149 >4J5U-A nrPDB Length = 420 Score = 28.4 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 27/77 (35%), Gaps = 2/77 (2%) Query: 26 NHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGY--KFFADLLDYIK 83 Y +++V + + D++ +HIV + + K G K A+ LD Sbjct: 281 PEYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAG 340 Query: 84 ALNRNSDRSIPMTVDFI 100 + T FI Sbjct: 341 ITCNKNAIPFDETSPFI 357 >4QDF-B nrPDB Length = 394 Score = 28.4 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 30/61 (49%), Gaps = 7/61 (11%) Query: 6 PGVVISD---DEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERL----ARDVMKEMG 58 P +I D + GYD++ I HY ++ + +G+I+ +++RL A ++ G Sbjct: 236 PSFMIDDLVYEYEGYDVESVLINCHYPVSQDKFVLMYGMIVKKSDRLEGEKALQTAQQFG 295 Query: 59 G 59 Sbjct: 296 N 296 >3QUP-A nrPDB Length = 323 Score = 28.0 bits (61), Expect = 2.9, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 31/95 (32%), Gaps = 12/95 (12%) Query: 19 LDLFCIPNHYAEDLERVFIPHGLIM----------DRTERLARDVMKEMGGHHIVALCVL 68 LD I + E LE V IP + +E G VA+ +L Sbjct: 2 LDSLGISDELKEKLEDVLIPEQQFTLGRMLGKGEFGSVRE--AQLKQEDGSFVKVAVKML 59 Query: 69 KGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLK 103 K +D+ ++++ + P + + Sbjct: 60 KADIIASSDIEEFLREAACMKEFDHPHVAKLVGVS 94 >2GQ0-A nrPDB Length = 303 Score = 27.6 bits (60), Expect = 3.9, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 11/71 (15%) Query: 96 TVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNP 155 + +I SY +S+ ++++ G VL++ D ID + +++ + +++ Sbjct: 201 KIYYITADSYAAAKSSPHLELLRK------KGIEVLLLSDRID-----EWMMNYLTEFDG 249 Query: 156 KMVKVASLLVK 166 K + S + + Sbjct: 250 KPFQSVSKVDE 260 >1L1R-A nrPDB Length = 186 Score = 27.6 bits (60), Expect = 3.9, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 18/38 (47%), Gaps = 2/38 (5%) Query: 130 VLIVEDIIDTGKTMQTLLSLVRQ--YNPKMVKVASLLV 165 VL+ +D++ TG T+ + L P+ + + L Sbjct: 120 VLLHDDVLATGGTLLAAIELCETAGVKPENIYINVLYE 157 >2OEL-A nrPDB Length = 413 Score = 27.6 bits (60), Expect = 4.5, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 39/105 (37%), Gaps = 15/105 (14%) Query: 109 QSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASL----- 163 Q+ G + ++ D++ L +L E I GK L + Q + + +L Sbjct: 164 QALGGVDLVKDDEI--LFDSELLPFEKRITEGK--AALQEVYEQTGKRTLYAVNLTGKTF 219 Query: 164 -LVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCV 207 L + R+ D + F V Y LD + R+ + V Sbjct: 220 ALKDKAKRAAELGADVLLFN-----VFAYGLDVLQALREDEEIAV 259 >6MZC-R nrPDB Length = 161 Score = 27.6 bits (60), Expect = 4.9, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 22/59 (37%), Gaps = 4/59 (6%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL----KGGYKFFADLLDYIKA 84 +DL R P+ + + E + + + + A C L K D+ +++ Sbjct: 64 QDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLER 122 >1MGT-A nrPDB Length = 174 Score = 27.2 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 24/78 (30%), Gaps = 2/78 (2%) Query: 15 PGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH--HIVALCVLKGGY 72 G + L P+ Y E + +V I L+ + + + V +G Sbjct: 50 RGVSISLDVQPSDYPEKVFKVLIGELDNASFLRELSFEGVTPFEKKVYEWLTKNVKRGSV 109 Query: 73 KFFADLLDYIKALNRNSD 90 + DL + R Sbjct: 110 ITYGDLAKALNTSPRAVG 127 >1Y4U-A nrPDB Length = 559 Score = 27.2 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 11/71 (15%) Query: 96 TVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNP 155 + +I SY +S+ ++++ G VL++ D ID + +++ + +++ Sbjct: 429 KIYYITADSYAAAKSSPHLELLRK------KGIEVLLLSDRID-----EWMMNYLTEFDG 477 Query: 156 KMVKVASLLVK 166 K + S + + Sbjct: 478 KPFQSVSKVDE 488 >2IOQ-A nrPDB Length = 624 Score = 27.2 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 33/71 (46%), Gaps = 11/71 (15%) Query: 96 TVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNP 155 + +I SY +S+ ++++ G VL++ D ID + +++ + +++ Sbjct: 429 KIYYITADSYAAAKSSPHLELLRK------KGIEVLLLSDRID-----EWMMNYLTEFDG 477 Query: 156 KMVKVASLLVK 166 K + S + + Sbjct: 478 KPFQSVSKVDE 488 >1H3O-B nrPDB Length = 76 Score = 27.2 bits (59), Expect = 5.8, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 22/59 (37%), Gaps = 4/59 (6%) Query: 30 EDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVL----KGGYKFFADLLDYIKA 84 +DL R P+ + + E + + + + A C L K D+ +++ Sbjct: 12 QDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLER 70 >5BO5-A nrPDB Length = 416 Score = 27.2 bits (59), Expect = 5.8, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 21/55 (38%) Query: 77 DLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVL 131 DLL + L +N I +KSY DI I G+D + K L Sbjct: 319 DLLKSLSRLAKNGMSKKHKKYADILIKSYAKGLEARDIATIVGEDSLSKEDKAYL 373 >3KJP-A nrPDB Length = 299 Score = 26.4 bits (57), Expect = 8.8, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 8/95 (8%) Query: 36 FIPHGLIMD--RTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSI 93 + G + R + L D++ H VA + G + L ++++N + + Sbjct: 201 LVLEGDLSHIHRLQNLTIDIL-VYDNHVHVARSLKVGSFLRIYSLHTKLQSMNSENQTML 259 Query: 94 PMTVDFIRLKSYCND-----QSTGDIKVIGGDDLS 123 + SY +S D+ + D S Sbjct: 260 SLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLES 294 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.145 0.386 Lambda K H 0.267 0.0443 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,272,949 Number of Sequences: 36641 Number of extensions: 375929 Number of successful extensions: 1406 Number of sequences better than 10.0: 104 Number of HSP's better than 10.0 without gapping: 135 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1186 Number of HSP's gapped (non-prelim): 169 length of query: 218 length of database: 10,336,785 effective HSP length: 93 effective length of query: 125 effective length of database: 6,929,172 effective search space: 866146500 effective search space used: 866146500 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.5 bits)