BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00491 (289 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2OC4-A nrPDB 600 e-172 4EAR-A nrPDB 590 e-169 1A9O-A nrPDB 528 e-151 2P4S-A nrPDB 329 8e-91 3KHS-A nrPDB 306 6e-84 3FNQ-A nrPDB 288 1e-78 6BHB-A nrPDB 266 7e-72 5IFK-A nrPDB 262 1e-70 4LNA-A nrPDB 251 3e-67 4M1E-A nrPDB 241 3e-64 3LA8-A nrPDB 234 3e-62 1VMK-A nrPDB 223 9e-59 4NS1-A nrPDB 222 1e-58 3ODG-A nrPDB 209 1e-54 1YQQ-A nrPDB 202 1e-52 4UC0-A nrPDB 175 2e-44 1G2O-A nrPDB 154 5e-38 1C3X-A nrPDB 128 2e-30 6DZ3-A nrPDB 76 2e-14 2A8Y-A nrPDB 66 2e-11 4L6I-A nrPDB 61 6e-10 3OZB-A nrPDB 61 6e-10 1V4N-A nrPDB 60 1e-09 1WTA-A nrPDB 59 2e-09 4GLJ-A nrPDB 48 5e-06 3QPB-A nrPDB 30 1.6 4R2W-A nrPDB 29 1.9 1XAI-A nrPDB 29 2.6 4AC9-A nrPDB 29 3.0 6AYO-A nrPDB 28 3.3 4YML-A nrPDB 28 3.6 4R31-A nrPDB 28 4.3 5LJ3-O nrPDB 28 5.3 6EZS-A nrPDB 27 7.8 2OVL-A nrPDB 27 8.7 >2OC4-A nrPDB Length = 289 Score = 600 bits (1547), Expect = e-172, Method: Compositional matrix adjust. Identities = 287/289 (99%), Positives = 287/289 (99%) Query: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDY EIPNFPRST Sbjct: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYSEIPNFPRST 60 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL Sbjct: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ Sbjct: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL Sbjct: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 ITNKVIMDYESLEKAN EEVLAAGKQAAQKLEQFVSILMASIPLPDKAS Sbjct: 241 ITNKVIMDYESLEKANDEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 >4EAR-A nrPDB Length = 324 Score = 590 bits (1522), Expect = e-169, Method: Compositional matrix adjust. Identities = 284/289 (98%), Positives = 287/289 (99%) Query: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 MENGYTYEDYKNTAE+LLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDY EIPNFPRST Sbjct: 36 MENGYTYEDYKNTAEYLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYSEIPNFPRST 95 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPL+KVTFPVRVFHLLGVDTLVVTNAAGGL Sbjct: 96 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLYKVTFPVRVFHLLGVDTLVVTNAAGGL 155 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALST+KQ Sbjct: 156 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTYKQ 215 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL Sbjct: 216 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 275 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 ITNKVIMDYESLEKAN EEVLAAGKQAAQKLEQFVSILMASIPLPDKAS Sbjct: 276 ITNKVIMDYESLEKANWEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 324 >1A9O-A nrPDB Length = 289 Score = 528 bits (1361), Expect = e-151, Method: Compositional matrix adjust. Identities = 249/284 (87%), Positives = 266/284 (93%) Query: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 M+NGYTYEDY++TA+WLLSHT+ RPQVA+ICGSGLGGL +KLTQAQ FDY EIPNFP ST Sbjct: 1 MQNGYTYEDYQDTAKWLLSHTEQRPQVAVICGSGLGGLVNKLTQAQTFDYSEIPNFPEST 60 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 VPGHAGRLVFG LNGRACVMMQGRFHMYEGYP WKVTFPVRVF LLGV+TLVVTNAAGGL Sbjct: 61 VPGHAGRLVFGILNGRACVMMQGRFHMYEGYPFWKVTFPVRVFRLLGVETLVVTNAAGGL 120 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 NP FEVGDIMLIRDHINLPGFSG+NPLRGPN+ERFG RFPAMSDAYDR MRQ+A STWKQ Sbjct: 121 NPNFEVGDIMLIRDHINLPGFSGENPLRGPNEERFGVRFPAMSDAYDRDMRQKAHSTWKQ 180 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 MGEQRELQEGTYVM+ GP+FETVAECR+L+ LGADAVGMSTVPEVIVARHCGLRVFGFSL Sbjct: 181 MGEQRELQEGTYVMLGGPNFETVAECRLLRNLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL 284 ITNKVIMD ES KANHEEVL AGKQAAQKLEQFVS+LMASIP+ Sbjct: 241 ITNKVIMDTESQGKANHEEVLEAGKQAAQKLEQFVSLLMASIPV 284 >2P4S-A nrPDB Length = 373 Score = 329 bits (844), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 156/279 (55%), Positives = 195/279 (69%) Query: 4 GYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPG 63 GYTY+ + A +LL T+ RP+V IICGSGLG L ++LT FDY IP+FP STV G Sbjct: 89 GYTYDTLQEIATYLLERTELRPKVGIICGSGLGTLAEQLTDVDSFDYETIPHFPVSTVAG 148 Query: 64 HAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPK 123 H GRLVFG+L G + MQGRFH YEGYPL K PVRV HL+G L+ TNAAGG NPK Sbjct: 149 HVGRLVFGYLAGVPVMCMQGRFHHYEGYPLAKCAMPVRVMHLIGCTHLIATNAAGGANPK 208 Query: 124 FEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGE 183 + VGDIMLI+DHINL GF+G NPL+GPNDERFG RF M++ YD + Q+A +Q+G Sbjct: 209 YRVGDIMLIKDHINLMGFAGNNPLQGPNDERFGPRFFGMANTYDPKLNQQAKVIARQIGI 268 Query: 184 QRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITN 243 + EL+EG Y + GP+FETVAE ++L LG DA+GMSTV E+I ARHCG+ F FSLITN Sbjct: 269 ENELREGVYTCLGGPNFETVAEVKMLSMLGVDAIGMSTVHEIITARHCGMTCFAFSLITN 328 Query: 244 KVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 M YE E+ H+ ++ GK + L +FVS ++ I Sbjct: 329 MCTMSYEEEEEHCHDSIVGVGKNREKTLGEFVSRIVKHI 367 >3KHS-A nrPDB Length = 285 Score = 306 bits (785), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 138/276 (50%), Positives = 191/276 (69%) Query: 7 YEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAG 66 Y+ K TA WL + RP + I+CGSGLG + D L + Y +IPNFP +V GHAG Sbjct: 4 YDLAKETAAWLNKQLQIRPVLGIVCGSGLGKIGDSLETSITVAYSDIPNFPVGSVKGHAG 63 Query: 67 RLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEV 126 L+FG +NG +CV M+GRFH+YEG+ + TFP+RVF LGV +V+TNAAGGLNP + Sbjct: 64 SLIFGSVNGVSCVCMKGRFHLYEGHTAARATFPMRVFKALGVKIVVLTNAAGGLNPSYRP 123 Query: 127 GDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRE 186 GD M++RDHINLPG +G NPL GPND+ G+RFP+M+ YD+T+R+ A+S +++G Sbjct: 124 GDFMVVRDHINLPGLAGANPLTGPNDDTEGERFPSMTSVYDKTLRKYAISAARELGMSYA 183 Query: 187 LQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVI 246 EG Y V GPSFET AEC++L+ +G+DAVGMST PE IVA+H G+R SLI+N + Sbjct: 184 THEGVYCCVNGPSFETPAECKILRLMGSDAVGMSTAPETIVAKHGGMRCLAVSLISNVIA 243 Query: 247 MDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + E+ + HEEVL AG++A+ ++ V +++ I Sbjct: 244 SNCETPAEPTHEEVLRAGEEASARMTALVKLVIEKI 279 >3FNQ-A nrPDB Length = 287 Score = 288 bits (738), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 136/276 (49%), Positives = 185/276 (67%) Query: 8 EDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGR 67 E+ K A + T P++ IICGSGLG L D + Y +IPNFP+++V GH+G Sbjct: 10 ENVKKVAHHIQKLTSIVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGN 69 Query: 68 LVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVG 127 L+FG L+GR V+MQGRFHMYEGY V P+RV LLGV L+V+NAAGGLN ++G Sbjct: 70 LIFGTLSGRKVVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLG 129 Query: 128 DIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQREL 187 D ++++DHI LPG N L GPN E FG RFPA+S+AYDR +R+ A+ ++ G + Sbjct: 130 DFVILKDHIYLPGLGLNNILVGPNQEAFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLV 189 Query: 188 QEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIM 247 +G YVM GP +ET AEC +L +G D VGMST+PEV++ARHCG++VF SL+TN ++ Sbjct: 190 HQGVYVMNGGPCYETPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVL 249 Query: 248 DYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIP 283 D ES K NHEEVLA G Q A+ ++ + ++ +P Sbjct: 250 DVESDLKPNHEEVLATGAQRAELMQSWFEKIIEKLP 285 >6BHB-A nrPDB Length = 287 Score = 266 bits (680), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 127/279 (45%), Positives = 176/279 (63%) Query: 6 TYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHA 65 YE+ A+++ + P + IICGSGLG L +++ + ++ Y IPNFP++TV GH Sbjct: 8 NYENASMAADYIKRVSNVLPDIGIICGSGLGKLIEEIEERKVIPYINIPNFPKTTVAGHV 67 Query: 66 GRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFE 125 G LV G + GR V MQGR HMYEGY ++ P+RV LLGV L++TN AGG+N K + Sbjct: 68 GNLVLGSVGGRKIVAMQGRLHMYEGYSNQEIALPIRVMKLLGVRVLLITNLAGGINRKLK 127 Query: 126 VGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQR 185 GD +LI+ HIN PG N L GPN + FG RFP +S+AYDR ++Q AL ++ Q Sbjct: 128 SGDFVLIKGHINFPGLGLNNVLVGPNQDEFGPRFPDLSNAYDRLLQQLALKIAQENDFQD 187 Query: 186 ELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKV 245 + EG Y GP++E+ E +L KLG D VGMSTVPEVI+A HCG++V SLI N Sbjct: 188 LVHEGVYAFNGGPTYESPDESNMLLKLGCDVVGMSTVPEVIIACHCGIKVLAVSLIANNS 247 Query: 246 IMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL 284 I+D E+ NHE+VLA ++ A L+ + ++ +PL Sbjct: 248 ILDAENDVSINHEKVLAVAEKRADLLQMWFKEIITRLPL 286 >5IFK-A nrPDB Length = 312 Score = 262 bits (669), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 128/273 (46%), Positives = 175/273 (64%), Gaps = 15/273 (5%) Query: 25 PQVAIICGSGLGGLTDKLT---QAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMM 81 P+ +ICGSGL G++ K+ + I Y IP F STVPGH+G L+FG++NG V+M Sbjct: 34 PKALVICGSGLSGISTKIADEPKPLILSYSTIPGFKVSTVPGHSGELIFGYMNGAPVVLM 93 Query: 82 QGRFHMYEGYPLWKVTFPVRVFHLLG-VDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPG 140 GR H YEG+ L + P+R HLLG ++ L+VTNAAGG+N F+ GD+M + DHIN PG Sbjct: 94 NGRLHSYEGHSLAETVHPIRALHLLGSINVLIVTNAAGGINASFKAGDLMCVYDHINFPG 153 Query: 141 FSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSF 200 G +PLRG N + FG RF A SDAYD +R+ S K++ +R++ EGTY V GP+F Sbjct: 154 LCGFHPLRGANFDEFGPRFLATSDAYDLELRKLLFSKKKELNIERKIHEGTYSYVHGPTF 213 Query: 201 ETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLE------- 253 E+ AE R L+ G DAVGMSTVPEV+ ARHCG RV SLITN+ ++D + Sbjct: 214 ESRAESRFLRLAGTDAVGMSTVPEVVTARHCGWRVLALSLITNECVVDPPASAHDENPVP 273 Query: 254 ----KANHEEVLAAGKQAAQKLEQFVSILMASI 282 KA HEEVL +A++ +++ + ++A I Sbjct: 274 IQEGKATHEEVLENSAKASKDVQELIFSVVAEI 306 >4LNA-A nrPDB Length = 293 Score = 251 bits (640), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 133/277 (48%), Positives = 177/277 (63%), Gaps = 9/277 (3%) Query: 2 ENGY---TYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPR 58 EN Y +E + T +++ S RP + II G+GLG LT++L Y IP+FP Sbjct: 16 ENLYFQSMFEQIQETTQFIQSKITLRPAIGIILGTGLGALTNELDIDTTIPYETIPHFPL 75 Query: 59 STVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAG 118 STV H+G+L+ G L G++ V+MQGRFH YEGY + +VT+PVRV H LG+ TL+V+NAAG Sbjct: 76 STVEFHSGKLLIGTLGGKSVVVMQGRFHYYEGYTMQQVTYPVRVMHALGIQTLLVSNAAG 135 Query: 119 GLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTW 178 G+NP F+ D+M+I DHI+L QNPL PN FGDRFP MS+ Y +++ A S Sbjct: 136 GMNPTFQTSDLMVIDDHISL--LLPQNPLICPNPPIFGDRFPDMSEPYRKSLIDLAFSVA 193 Query: 179 KQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGF 238 ++ L+ G YV V GP ET AE R+L++ GADAVGMSTVPEVIVA G+ VFG Sbjct: 194 AEL--DIPLKRGVYVSVTGPQLETRAEYRMLRQWGADAVGMSTVPEVIVANQLGMDVFGI 251 Query: 239 SLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFV 275 S+IT+ D +LEKA ++LA QA KL + Sbjct: 252 SVITDLCFPD--TLEKAELVKILATAAQAEPKLTMLI 286 >4M1E-A nrPDB Length = 297 Score = 241 bits (614), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 126/260 (48%), Positives = 168/260 (64%), Gaps = 7/260 (2%) Query: 25 PQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGR 84 P V +I G+GLGGL +++ Q Y +IP+FP STV HAGRLV G L G V M+GR Sbjct: 45 PAVGMILGTGLGGLAEQIEQDIAIPYSDIPHFPTSTVKSHAGRLVCGRLRGIPIVAMEGR 104 Query: 85 FHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ 144 FH YEGY L +VTFPVRV +GV TL+VTNAAGG+NP+ ++ D+++I DHINL + Sbjct: 105 FHYYEGYSLEQVTFPVRVMKAMGVKTLLVTNAAGGINPQLDLSDVLIIEDHINL---MPE 161 Query: 145 NPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVA 204 NPLRGPNDE G RFP MS YD + A ++G +G +V V+GP+ ET A Sbjct: 162 NPLRGPNDEELGPRFPDMSHPYDCQHMEVARQVALELGIH--CPKGVFVAVSGPNLETRA 219 Query: 205 ECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAG 264 E R+L+ +GAD VGMSTVPEV+VA H GLRV GFS++T+ + D +LE ++L Sbjct: 220 EYRMLKLMGADVVGMSTVPEVLVAVHAGLRVLGFSVVTDLCLPD--ALEPVELNKILEVA 277 Query: 265 KQAAQKLEQFVSILMASIPL 284 + KL + + ++ I L Sbjct: 278 ARGGAKLARLIPEILPRIAL 297 >3LA8-A nrPDB Length = 303 Score = 234 bits (598), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 126/270 (46%), Positives = 172/270 (63%), Gaps = 10/270 (3%) Query: 13 TAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGF 72 T ++L + +P+ +I GSGLG L +++ A + +Y +IPN+ RSTV GHAG+L++G Sbjct: 44 TRDFLTAKGVQKPEFGLILGSGLGELAEEIENALVLNYADIPNWGRSTVSGHAGKLIYGE 103 Query: 73 LNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLI 132 L GR + +QGRFH YEG + VTFP+R+ LG L+VTNAAGG+ F G +M I Sbjct: 104 LAGRKVLALQGRFHYYEGNSMELVTFPIRIMKALGCQGLIVTNAAGGIG--FGPGTLMAI 161 Query: 133 RDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTY 192 DHINL +G NPL G N + FG RFP MS+AY R+ A ++G + L EG Y Sbjct: 162 SDHINL---TGANPLMGENLDDFGFRFPDMSNAYTADYREVAHQVADKIGIK--LDEGVY 216 Query: 193 VMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESL 252 + V+GPS+ET AE R + LGADAVGMSTVPEVIVA H GL+V G S ITN ++S Sbjct: 217 IGVSGPSYETPAEIRAFKTLGADAVGMSTVPEVIVAVHSGLKVLGISAITNYA-AGFQS- 274 Query: 253 EKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + NHEEV+A +Q + + V ++ + Sbjct: 275 -ELNHEEVVAVTQQIKEDFKGLVKAILVEL 303 >1VMK-A nrPDB Length = 277 Score = 223 bits (567), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 122/259 (47%), Positives = 166/259 (64%), Gaps = 14/259 (5%) Query: 16 WLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNG 75 ++ T P + II GSG G +K+ I DY +IP+FP+ TV GH+G+LVFG ++ Sbjct: 23 FISERTNLSPDILIILGSGFGPFIEKVEDPVIIDYKDIPHFPQPTVEGHSGKLVFGRISD 82 Query: 76 RACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDH 135 + ++M GRFH+YEG+ V FPV + +GV +VVTNAAG +NP+F+ G+I+L+RD Sbjct: 83 KPVMIMAGRFHLYEGHDPATVAFPVYLAKYVGVKGVVVTNAAGAINPEFKPGEIILVRDI 142 Query: 136 INLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTW-KQMGEQRELQEGTYVM 194 IN F +NPLRGPNDE+ G RFP MS D W +++ E+ L+EG Y+ Sbjct: 143 IN---FMFRNPLRGPNDEKIGPRFPDMSSVVD--------PEWARKIQERLSLKEGVYIG 191 Query: 195 VAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEK 254 V GPS+ET AE RV +KLGAD VGMSTVPEVI A+HCGL+V FS +TN + Sbjct: 192 VLGPSYETPAEIRVFEKLGADLVGMSTVPEVIAAKHCGLKVVVFSCVTNMAAGITHG--R 249 Query: 255 ANHEEVLAAGKQAAQKLEQ 273 +HEEV+ K A K+E+ Sbjct: 250 LSHEEVVRTTKMAQGKIEK 268 >4NS1-A nrPDB Length = 295 Score = 222 bits (566), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 125/276 (45%), Positives = 175/276 (63%), Gaps = 9/276 (3%) Query: 8 EDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGR 67 + Y A +L S + AII GSGLG L +K+ + Y EIP+F ++T GH G Sbjct: 28 QHYHEAASFLSSRLPGDAKTAIILGSGLGELAEKIENKTVIPYNEIPHFAQATAVGHKGN 87 Query: 68 LVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVG 127 ++ G L G V MQGRFH YEGY + +VTFP+RV LLG++ L V+NAAGG+N F+VG Sbjct: 88 IIGGILGGTPVVAMQGRFHYYEGYSMDQVTFPIRVMKLLGIENLFVSNAAGGINTSFKVG 147 Query: 128 DIMLIRDHI-NLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRE 186 D+M+I DHI NLP NPL GPN + FG RFP M+ AYDR +A +++ Sbjct: 148 DLMIICDHINNLP-----NPLIGPNMDMFGVRFPDMTRAYDREFIAKAKGIAQEL--NIP 200 Query: 187 LQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVI 246 ++EG YV + GPS+ET AE + ++G DA+GMSTVPEVIVARH G+RVFG S+ITN+ Sbjct: 201 VKEGVYVGLTGPSYETPAEYKFWGQVGGDAIGMSTVPEVIVARHTGIRVFGMSVITNEGY 260 Query: 247 MDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + + ++V+ A A++K+ + L+A++ Sbjct: 261 HFADDFVN-DEQDVIRAANAASEKMGAIFARLIAAV 295 >3ODG-A nrPDB Length = 287 Score = 209 bits (532), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 112/259 (43%), Positives = 155/259 (59%), Gaps = 9/259 (3%) Query: 24 RPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQG 83 +PQ+A I GSGLG L D++T Y +IP FP S+V GHAG LV G L G + M+G Sbjct: 33 KPQIAFILGSGLGDLVDQITNDTTISYADIPGFPVSSVHGHAGELVLGDLCGVPVMCMKG 92 Query: 84 RFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHIN-LPGFS 142 R H YEG + +T PVR F L+G + L TNAAG L P+ G +++++DHIN +PG Sbjct: 93 RGHFYEGKGMSIMTNPVRTFKLMGCEFLFCTNAAGSLRPEVLPGSVVMLKDHINTMPG-- 150 Query: 143 GQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFET 202 PL GPND+RFG RF ++++AYD+ +R +Q+ L EG +V GP FET Sbjct: 151 --TPLVGPNDDRFGPRFFSLANAYDKDLRADMAKIAQQL--DIPLTEGVFVSYPGPCFET 206 Query: 203 VAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLA 262 AE R++Q +G D VGMS VPEV+ A HCGL+V + ITN + + S +HE+ L Sbjct: 207 PAEIRMMQIIGGDVVGMSVVPEVLSAAHCGLKVIALTAITN--LAEGLSDVVLSHEQTLK 264 Query: 263 AGKQAAQKLEQFVSILMAS 281 K A+ + + + S Sbjct: 265 FAKVASVNFTKLIEAFLKS 283 >1YQQ-A nrPDB Length = 277 Score = 202 bits (514), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 114/259 (44%), Positives = 152/259 (58%), Gaps = 9/259 (3%) Query: 25 PQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGR 84 P+VA I GSGLG L D++ A Y ++P FP STV GHAG LV G L G V M+GR Sbjct: 26 PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85 Query: 85 FHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHIN-LPGFSG 143 H YEG + +T +R F LLG + L TNAAG L P+ G ++ ++DHIN +PG Sbjct: 86 GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG--- 142 Query: 144 QNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETV 203 P+ G ND+RFG+RF ++++AYD R K+ E L EG +V GP+FET Sbjct: 143 -TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVSYPGPNFETA 199 Query: 204 AECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAA 263 AE R++Q +G D VGMS VPEVI ARHC L+V S ITN + + S K +H + LAA Sbjct: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN--MAEGLSDVKLSHAQTLAA 257 Query: 264 GKQAAQKLEQFVSILMASI 282 + + Q + + I Sbjct: 258 AELSKQNFINLICGFLRKI 276 >4UC0-A nrPDB Length = 291 Score = 175 bits (443), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 101/223 (45%), Positives = 129/223 (57%), Gaps = 16/223 (7%) Query: 25 PQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGR 84 P++AI+ GSGLGGL D++ A + +IP FP+ V GHA LV G G+ +M+ GR Sbjct: 39 PRIAIVLGSGLGGLVDEVENAVRIPFADIPGFPQGGVSGHAKELVAGLFAGQPIIMLAGR 98 Query: 85 FHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ 144 H YE + P+ LGV TL++TNAAG L G +M + DHIN FSG Sbjct: 99 VHYYEEGDAAAMRLPIETLASLGVTTLILTNAAGSLRADMPPGSVMQLIDHIN---FSGH 155 Query: 145 NPLRGPNDERFGDRFPAMSDAYD----RTMRQRALSTWKQMGEQRELQEGTYVMVAGPSF 200 NPL G + RF M+ AYD MR+ A + E L G Y+ +GPSF Sbjct: 156 NPLIGETGD---GRFVGMTQAYDGELAEAMRRAADA------EDISLSSGVYMWFSGPSF 206 Query: 201 ETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITN 243 ET AE R+ + LGADAVGMSTVPEVI+AR GL+V S+ITN Sbjct: 207 ETPAEIRMARTLGADAVGMSTVPEVILARFFGLKVAAASVITN 249 >1G2O-A nrPDB Length = 268 Score = 154 bits (388), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 102/261 (39%), Positives = 138/261 (52%), Gaps = 31/261 (11%) Query: 27 VAIICGSG-------LGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACV 79 VA++ GSG LG T L QA E+P F T GHAG L+ + + Sbjct: 30 VAVVLGSGWLPAVAALGSPTTVLPQA------ELPGFVPPTAAGHAGELLSVPIGAHRVL 83 Query: 80 MMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLP 139 ++ GR H YEG+ L V PVR G +V+TNAAGGL +VG +LI DH+NL Sbjct: 84 VLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQVGQPVLISDHLNL- 142 Query: 140 GFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPS 199 + ++PL G F ++DAY +R+ A + Q L EG Y + GP Sbjct: 143 --TARSPL-------VGGEFVDLTDAYSPRLRELARQSDPQ------LAEGVYAGLPGPH 187 Query: 200 FETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEE 259 +ET AE R+LQ LGAD VGMSTV E I AR G V G SL+TN + + E +H E Sbjct: 188 YETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTN--LAAGITGEPLSHAE 245 Query: 260 VLAAGKQAAQKLEQFVSILMA 280 VLAAG +A ++ ++ ++A Sbjct: 246 VLAAGAASATRMGALLADVIA 266 >1C3X-A nrPDB Length = 266 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 93/259 (35%), Positives = 133/259 (51%), Gaps = 28/259 (10%) Query: 26 QVAIICGSGLGGLTDKLTQ--AQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQG 83 +A++ GSG GG + L + A++ + EIP F T + R+ + R +++ Sbjct: 31 DMALVLGSGWGGAAELLGEVVAEVPTH-EIPGFSSVT---RSIRVERADGSVRHALVLGS 86 Query: 84 RFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSG 143 R H+YEG + V VR G +TL++TN GGLN ++ G +L+ DHINL + Sbjct: 87 RTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEWGAGTPVLLSDHINL---TA 143 Query: 144 QNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETV 203 ++PL GP F ++D Y +R+ A L EG Y GP +ET Sbjct: 144 RSPLEGPT-------FVDLTDVYSPRLRELAHRV------DPTLPEGVYAQFPGPHYETP 190 Query: 204 AECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAA 263 AE R+ LGAD VGMST E I ARHCGL V G SL+TN + S +H EV+ A Sbjct: 191 AEVRMAGILGADLVGMSTTLEAIAARHCGLEVLGVSLVTN--LAAGISPTPLSHAEVIEA 248 Query: 264 GKQAAQKLEQFVSILMASI 282 G+ A + +S L+A I Sbjct: 249 GQAAGPR----ISALLADI 263 >6DZ3-A nrPDB Length = 297 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/224 (27%), Positives = 107/224 (47%), Gaps = 20/224 (8%) Query: 68 LVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLL--GVDTLVVTNAAGGLNPKFE 125 L+ G + CV++ + P KV + ++ L G ++VT A G L + + Sbjct: 59 LILGKIKNVDCVLLARHGRQHTIMPS-KVNYQANIWALKEEGCTHVIVTTACGSLREEIQ 117 Query: 126 VGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQR 185 GDI++I I+ Q+ G + G M++ + R+ + T K++G R Sbjct: 118 PGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLG-LR 176 Query: 186 ELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKV 245 +GT V + GP F + AE + + GAD + M+TVPEV++A+ G+ ++ T Sbjct: 177 CHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMAT--- 233 Query: 246 IMDYESLEKANHEE------VLAAGKQAAQKLEQFVSILMASIP 283 DY+ ++ HEE VL K+ A K + S+L+ +IP Sbjct: 234 --DYDCWKE--HEEAVSVDRVLKTLKENANKAK---SLLLTTIP 270 >2A8Y-A nrPDB Length = 270 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 65/269 (24%), Positives = 122/269 (45%), Gaps = 31/269 (11%) Query: 23 HRPQVAIICGSGL--GGLTDKLTQAQIFD-YGEIPNFPRSTVPGHAGRLVFGFLNGRACV 79 + + II GSGL G+ + + +++ YG+ +F G G FL Sbjct: 6 EKASIGIIGGSGLYDPGIFSESKEIKVYTPYGQPSDF---ITIGKIGNKSVAFLP----- 57 Query: 80 MMQGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHIN 137 GR H P K+ + ++ L LGV ++ +A G L +++GD ++ I+ Sbjct: 58 -RHGRGHRI---PPHKINYRANIWALKELGVRWVISVSAVGSLRMDYKLGDFVIPDQFID 113 Query: 138 LPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAG 197 + + GP +M+D + ++R+ A+ T K++ + + GTY+ + G Sbjct: 114 MTKNREYSFFDGPVVAHV-----SMADPFCNSLRKLAIETAKELNIKTH-ESGTYICIEG 167 Query: 198 PSFETVAECRVLQKL-GADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEK-- 254 P F T AE R +++ AD +GM+ VPEV +A + +++T DY+ + Sbjct: 168 PRFSTRAESRTWREVYKADIIGMTLVPEVNLACEAQMCYATIAMVT-----DYDVFAEIP 222 Query: 255 ANHEEVLAAGKQAAQKLEQFVSILMASIP 283 EEV + +K ++ + L+ +P Sbjct: 223 VTAEEVTRVMAENTEKAKKLLYALIQKLP 251 >4L6I-A nrPDB Length = 320 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 69/250 (27%), Positives = 111/250 (44%), Gaps = 42/250 (16%) Query: 19 SHTKHRPQVAIICGSGLG--GLTDKLTQAQIFD-YGEIPNFPRSTVPGHAGRLVFGFLNG 75 SH + +V II GSG L K+ Q+ +G+ P T LV GF+ Sbjct: 19 SHMMSKVKVGIIGGSGFDDPNLFKKVGVRQVTTPFGK----PSDT-------LVEGFVGD 67 Query: 76 RACVMM--QGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIML 131 ACV++ G+ H+ P +V + V+ L LG ++ TNA G L GD ++ Sbjct: 68 VACVVLPRHGKGHLI---PPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVV 124 Query: 132 IRDHINLP-----GFSGQNP--LRG----PNDERFGDRFPAMSDAYDRTMRQRALSTW-- 178 + ++ F G P L+G P E F +R + R ++++ + Sbjct: 125 LNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCER---TRQILIQAARNKSINVYDK 181 Query: 179 KQMGEQRELQ-----EGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGL 233 K M + + EG+ V + GP F T E + + +G D V M+ VPEV +AR GL Sbjct: 182 KTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGL 241 Query: 234 RVFGFSLITN 243 +++T+ Sbjct: 242 SYASIAIVTD 251 >3OZB-A nrPDB Length = 259 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 62/241 (25%), Positives = 101/241 (41%), Gaps = 21/241 (8%) Query: 28 AIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHM 87 AII G+GL L + LT ++ E P + + P GR GR + + H Sbjct: 19 AIIGGTGLTQL-EGLTLSESLPI-ETP-YGAPSAPLQRGRYA-----GREVLFLARHGHP 70 Query: 88 YEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQN 145 + +P +V + ++ L G + ++ NA GG++ G + + I+ Sbjct: 71 HR-FPPHQVNYRANLWALKQAGAEAVIAVNAVGGIHAAMGTGHLCVPHQLIDYTSGREHT 129 Query: 146 PLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAE 205 G + F S YD +RQR + + +G G Y GP ETVAE Sbjct: 130 YFAGDIEHVTHIDF---SHPYDEPLRQRLIEALRALGLAHS-SHGVYACTQGPRLETVAE 185 Query: 206 CRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKV------IMDYESLEKANHEE 259 L++ G D VGM+ +PE +AR L +L+ N I+ +E+A H+ Sbjct: 186 IARLERDGNDIVGMTGMPEAALARELDLPYACLALVVNPAAGKSAGIITMAEIEQALHDG 245 Query: 260 V 260 + Sbjct: 246 I 246 >1V4N-A nrPDB Length = 281 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 65/277 (23%), Positives = 121/277 (43%), Gaps = 35/277 (12%) Query: 17 LLSHTKHRPQVAIICGSGLGG--LTDKLTQAQIFD-YGEIPNFPRSTVPGHAGRLVFGFL 73 ++ K + + II GSGL + + + +++ YGE + ++ G L Sbjct: 1 MMIEPKEKASIGIIGGSGLYDPQILTNVKEIKVYTPYGE-----------PSDNIILGEL 49 Query: 74 NGRACVMM--QGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDI 129 GR + GR H P K+ + ++ L LGV ++ +A G L ++ GD Sbjct: 50 EGRKVAFLPRHGRGHRI---PPHKINYRANIWALKSLGVKWVIAVSAVGSLRLDYKPGDF 106 Query: 130 MLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQE 189 ++ I++ GP +M+D + +R L + K +G + Sbjct: 107 VVPNQFIDMTKGRTYTFFDGPTVAHV-----SMADPFCEHLRSIILDSAKDLGITTH-DK 160 Query: 190 GTYVMVAGPSFETVAECRVLQKL-GADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMD 248 GTY+ + GP F T AE V +++ AD +GM+ VPEV +A + +S+I ++ D Sbjct: 161 GTYICIEGPRFSTRAESIVWKEVFKADIIGMTLVPEVNLACEAEM---CYSVI--GMVTD 215 Query: 249 YESLEK--ANHEEVLAAGKQAAQKLEQFVSILMASIP 283 Y+ EEV + K+++ + ++ +P Sbjct: 216 YDVFADIPVTAEEVTKVMAENTAKVKKLLYEVIRRLP 252 >1WTA-A nrPDB Length = 275 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 66/273 (24%), Positives = 118/273 (43%), Gaps = 25/273 (9%) Query: 24 RPQVAIICGSGL--GGLTDKLTQAQIFD-YGEIPNFPRSTVPGHAGRLVFGFLNGRACVM 80 R V +I GSGL G+ + + ++ YG +F V G + FL Sbjct: 11 RAHVGVIGGSGLYDPGIVENPVEVKVSTPYGNPSDF---IVVGDVAGVKVAFLP------ 61 Query: 81 MQGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINL 138 GR H P + + ++ L LGV ++ +A G L + GD ++ I++ Sbjct: 62 RHGRGHRI---PPHAINYRANIWALKALGVKWVISVSAVGSLREDYRPGDFVVPDQFIDM 118 Query: 139 PGFSGQNPL-RGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAG 197 GP +M+D + +RQR + + +++G + GTYV + G Sbjct: 119 TKNRRHYTFYDGPVTVHV-----SMADPFCEDLRQRLIDSGRRLGYTVH-ERGTYVCIEG 172 Query: 198 PSFETVAECRVLQKL-GADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKAN 256 P F T AE RV + + AD +GM+ VPE+ +A L +++T+ + + Sbjct: 173 PRFSTRAESRVWKDVFKADIIGMTLVPEINLACEAQLCYATLAMVTDYDVWADRPVTAEE 232 Query: 257 HEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 E V+ + + A+++ V +A P ++ S Sbjct: 233 VERVMISNVERARRMLYDVIPKLAGEPELERCS 265 >4GLJ-A nrPDB Length = 297 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 57/239 (23%), Positives = 92/239 (38%), Gaps = 44/239 (18%) Query: 22 KHRPQVAIICGSGL---GGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRAC 78 K+ +AII GSGL LT+K + YGE + +V G LNG Sbjct: 11 KNAADIAIIGGSGLYQMQALTNKRSVKIETPYGE-----------PSDDIVLGELNGVTV 59 Query: 79 VMMQGRFHMYEGYPLWKVTFPVRV----FHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRD 134 + +G+ L P R LGV +V +A G L + D+++ Sbjct: 60 AFLTRHG---QGHRLTPSEVPYRANIYALKTLGVRYIVSVSAVGSLQETLKPLDMVIPDQ 116 Query: 135 HINLP----------GFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQ 184 I++ G + P D + AYD + + Sbjct: 117 MIDMTKQRVSTFFGDGAVAHVSMADPLCPEVAD---ILIRAYDNA----------DIADG 163 Query: 185 RELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITN 243 + + TYV + GP F T AE +++ AD +GM+ +PE +AR + +L+T+ Sbjct: 164 QCHAKATYVCIEGPQFSTRAESHWYRQMQADIIGMTNMPEAKLAREASIAYATLALVTD 222 >3QPB-A nrPDB Length = 282 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 17/139 (12%) Query: 103 FHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ-NPLRGPNDERFGDRFPA 161 L G DT + GG+ + GDI++ I + G S + P+ FPA Sbjct: 107 LKLCGADTFIRVGTCGGIELDVKGGDIVIATGAIRMEGTSKEYAPI----------EFPA 156 Query: 162 MSD-----AYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGP-SFETVAECRVLQKLGAD 215 ++D A ++ ++ + + ++ G + P S+E + + ++LG Sbjct: 157 VADLEVTNALVNAAKKLGYTSHAGVVQCKDAFYGQHEPERMPVSYELLNKWEAWKRLGTK 216 Query: 216 AVGMSTVPEVIVARHCGLR 234 A M + + A H G+R Sbjct: 217 ASEMESAALFVAASHLGVR 235 >4R2W-A nrPDB Length = 252 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 106 LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFS 142 LGV+T + G + P VGD+++ + + L G S Sbjct: 82 LGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGAS 118 >1XAI-A nrPDB Length = 354 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 18/36 (50%) Query: 2 ENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGG 37 E T+E Y+ T E++LSH R I G G G Sbjct: 68 EKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATG 103 >4AC9-A nrPDB Length = 482 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 2/29 (6%) Query: 111 LVVTNAAGGLNPKFEVGDIMLIRDHINLP 139 L+V +A G PK + G+ MLI DH N+P Sbjct: 101 LIVVDAKEG--PKTQTGEHMLILDHFNIP 127 >6AYO-A nrPDB Length = 238 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 106 LGVDTLVVTNAAGGLNPKFEVGDIM 130 G L+ T AG NP+ E+GD++ Sbjct: 76 FGAQVLLFTGVAGAFNPELEIGDLL 100 >4YML-A nrPDB Length = 245 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 17/23 (73%) Query: 109 DTLVVTNAAGGLNPKFEVGDIML 131 D ++ T +AGGL P +VGDI++ Sbjct: 69 DVIINTGSAGGLAPTLKVGDIVV 91 >4R31-A nrPDB Length = 279 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 95 KVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ-NPLRGPNDE 153 V+ V LGV T + G + P VGD+++ + L G S PL P Sbjct: 93 SVSICVEELAQLGVGTFLRIGTTGAIQPYINVGDVLVTTGAVRLDGASRHFAPLEYPAVA 152 Query: 154 RF 155 F Sbjct: 153 DF 154 >5LJ3-O nrPDB Length = 590 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 12/47 (25%), Positives = 28/47 (59%) Query: 239 SLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLP 285 +++T K ++ +E ++ N + +GKQ ++ +F+ + AS+P P Sbjct: 330 TVLTPKELLPHEPGQEDNERSNIKSGKQLKSRIRKFLVQMFASLPSP 376 >6EZS-A nrPDB Length = 652 Score = 27.3 bits (59), Expect = 7.8, Method: Compositional matrix adjust. Identities = 25/113 (22%), Positives = 50/113 (44%), Gaps = 4/113 (3%) Query: 175 LSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHC--G 232 + W+ + E E Q T++ F T E R + A+ G++ +PE+ V HC Sbjct: 320 IGAWRGIDETIEPQY-THLSQRYGGFYTQEEIRDVIAF-AEQRGITIIPEIDVPGHCRAA 377 Query: 233 LRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLP 285 ++ LI + +Y S++ N + A + + +++ + + A P P Sbjct: 378 IKSLPHLLIEAEDTTEYRSIQHYNDNVINPALPGSYEFIDKVLEEIAALFPAP 430 >2OVL-A nrPDB Length = 371 Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 65/175 (37%), Gaps = 44/175 (25%) Query: 92 PLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFS------GQN 145 PLWK L G VV AGG++ + V D+ D GF G+ Sbjct: 122 PLWK---------LFGGYDPVVPVYAGGIDLELPVADLKTQADRFLAGGFRAIKMKVGRP 172 Query: 146 PLRGPND------ERFGDRFPAMSDA-----YDRTMR-QRALST----WKQ--------M 181 L+ D E GD FP M DA D +R RAL+ W + + Sbjct: 173 DLKEDVDRVSALREHLGDSFPLMVDANMKWTVDGAIRAARALAPFDLHWIEEPTIPDDLV 232 Query: 182 GEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVF 236 G R ++E + + G + T+ + A G T+PE V+ G F Sbjct: 233 GNARIVRESGHTIAGGENLHTLYDFH-----NAVRAGSLTLPEPDVSNIGGYTTF 282 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2OC4-A nrPDB 452 e-128 4EAR-A nrPDB 442 e-125 1A9O-A nrPDB 434 e-122 2P4S-A nrPDB 377 e-105 3FNQ-A nrPDB 371 e-103 3KHS-A nrPDB 364 e-101 6BHB-A nrPDB 363 e-101 4LNA-A nrPDB 339 9e-94 4M1E-A nrPDB 323 8e-89 3ODG-A nrPDB 320 5e-88 3LA8-A nrPDB 317 3e-87 5IFK-A nrPDB 316 5e-87 4NS1-A nrPDB 313 6e-86 1YQQ-A nrPDB 307 3e-84 1VMK-A nrPDB 295 2e-80 4UC0-A nrPDB 264 3e-71 2A8Y-A nrPDB 262 2e-70 1V4N-A nrPDB 261 2e-70 1WTA-A nrPDB 256 8e-69 6DZ3-A nrPDB 251 3e-67 1G2O-A nrPDB 241 2e-64 1C3X-A nrPDB 224 3e-59 4L6I-A nrPDB 211 3e-55 4GLJ-A nrPDB 201 2e-52 3OZB-A nrPDB 198 2e-51 Sequences not found previously or not previously below threshold: 4JWT-A nrPDB 43 1e-04 3QPB-A nrPDB 42 4e-04 1ODL-A nrPDB 35 0.042 3MB8-A nrPDB 34 0.065 4R31-A nrPDB 34 0.092 3TL6-A nrPDB 33 0.14 4WKO-A nrPDB 32 0.27 4U0O-B nrPDB 32 0.31 6AYO-A nrPDB 32 0.40 4C1L-A nrPDB 31 0.69 3PNS-A nrPDB 30 0.81 4M3N-A nrPDB 30 0.91 2AMY-A nrPDB 30 1.1 4TYM-A nrPDB 30 1.7 4YML-A nrPDB 29 2.6 6CFS-A nrPDB 29 2.7 4G89-A nrPDB 29 2.9 4MPH-A nrPDB 28 3.3 3UAY-A nrPDB 28 3.8 1WG8-A nrPDB 28 4.7 4XEU-A nrPDB 28 4.9 4JPF-A nrPDB 28 5.0 4R2W-A nrPDB 28 6.8 1XAI-A nrPDB 27 9.3 >2OC4-A nrPDB Length = 289 Score = 452 bits (1164), Expect = e-128, Method: Composition-based stats. Identities = 287/289 (99%), Positives = 287/289 (99%) Query: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDY EIPNFPRST Sbjct: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYSEIPNFPRST 60 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL Sbjct: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ Sbjct: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL Sbjct: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 ITNKVIMDYESLEKAN EEVLAAGKQAAQKLEQFVSILMASIPLPDKAS Sbjct: 241 ITNKVIMDYESLEKANDEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 >4EAR-A nrPDB Length = 324 Score = 442 bits (1138), Expect = e-125, Method: Composition-based stats. Identities = 284/289 (98%), Positives = 287/289 (99%) Query: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 MENGYTYEDYKNTAE+LLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDY EIPNFPRST Sbjct: 36 MENGYTYEDYKNTAEYLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYSEIPNFPRST 95 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPL+KVTFPVRVFHLLGVDTLVVTNAAGGL Sbjct: 96 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLYKVTFPVRVFHLLGVDTLVVTNAAGGL 155 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALST+KQ Sbjct: 156 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTYKQ 215 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL Sbjct: 216 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 275 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 ITNKVIMDYESLEKAN EEVLAAGKQAAQKLEQFVSILMASIPLPDKAS Sbjct: 276 ITNKVIMDYESLEKANWEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 324 >1A9O-A nrPDB Length = 289 Score = 434 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 249/284 (87%), Positives = 266/284 (93%) Query: 1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 M+NGYTYEDY++TA+WLLSHT+ RPQVA+ICGSGLGGL +KLTQAQ FDY EIPNFP ST Sbjct: 1 MQNGYTYEDYQDTAKWLLSHTEQRPQVAVICGSGLGGLVNKLTQAQTFDYSEIPNFPEST 60 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 VPGHAGRLVFG LNGRACVMMQGRFHMYEGYP WKVTFPVRVF LLGV+TLVVTNAAGGL Sbjct: 61 VPGHAGRLVFGILNGRACVMMQGRFHMYEGYPFWKVTFPVRVFRLLGVETLVVTNAAGGL 120 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 NP FEVGDIMLIRDHINLPGFSG+NPLRGPN+ERFG RFPAMSDAYDR MRQ+A STWKQ Sbjct: 121 NPNFEVGDIMLIRDHINLPGFSGENPLRGPNEERFGVRFPAMSDAYDRDMRQKAHSTWKQ 180 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 MGEQRELQEGTYVM+ GP+FETVAECR+L+ LGADAVGMSTVPEVIVARHCGLRVFGFSL Sbjct: 181 MGEQRELQEGTYVMLGGPNFETVAECRLLRNLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL 284 ITNKVIMD ES KANHEEVL AGKQAAQKLEQFVS+LMASIP+ Sbjct: 241 ITNKVIMDTESQGKANHEEVLEAGKQAAQKLEQFVSLLMASIPV 284 >2P4S-A nrPDB Length = 373 Score = 377 bits (968), Expect = e-105, Method: Composition-based stats. Identities = 156/279 (55%), Positives = 195/279 (69%) Query: 4 GYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPG 63 GYTY+ + A +LL T+ RP+V IICGSGLG L ++LT FDY IP+FP STV G Sbjct: 89 GYTYDTLQEIATYLLERTELRPKVGIICGSGLGTLAEQLTDVDSFDYETIPHFPVSTVAG 148 Query: 64 HAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPK 123 H GRLVFG+L G + MQGRFH YEGYPL K PVRV HL+G L+ TNAAGG NPK Sbjct: 149 HVGRLVFGYLAGVPVMCMQGRFHHYEGYPLAKCAMPVRVMHLIGCTHLIATNAAGGANPK 208 Query: 124 FEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGE 183 + VGDIMLI+DHINL GF+G NPL+GPNDERFG RF M++ YD + Q+A +Q+G Sbjct: 209 YRVGDIMLIKDHINLMGFAGNNPLQGPNDERFGPRFFGMANTYDPKLNQQAKVIARQIGI 268 Query: 184 QRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITN 243 + EL+EG Y + GP+FETVAE ++L LG DA+GMSTV E+I ARHCG+ F FSLITN Sbjct: 269 ENELREGVYTCLGGPNFETVAEVKMLSMLGVDAIGMSTVHEIITARHCGMTCFAFSLITN 328 Query: 244 KVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 M YE E+ H+ ++ GK + L +FVS ++ I Sbjct: 329 MCTMSYEEEEEHCHDSIVGVGKNREKTLGEFVSRIVKHI 367 >3FNQ-A nrPDB Length = 287 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 136/278 (48%), Positives = 185/278 (66%) Query: 6 TYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHA 65 E+ K A + T P++ IICGSGLG L D + Y +IPNFP+++V GH+ Sbjct: 8 NIENVKKVAHHIQKLTSIVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHS 67 Query: 66 GRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFE 125 G L+FG L+GR V+MQGRFHMYEGY V P+RV LLGV L+V+NAAGGLN + Sbjct: 68 GNLIFGTLSGRKVVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLK 127 Query: 126 VGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQR 185 +GD ++++DHI LPG N L GPN E FG RFPA+S+AYDR +R+ A+ ++ G Sbjct: 128 LGDFVILKDHIYLPGLGLNNILVGPNQEAFGTRFPALSNAYDRDLRKLAVQVAEENGFGN 187 Query: 186 ELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKV 245 + +G YVM GP +ET AEC +L +G D VGMST+PEV++ARHCG++VF SL+TN Sbjct: 188 LVHQGVYVMNGGPCYETPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNIS 247 Query: 246 IMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIP 283 ++D ES K NHEEVLA G Q A+ ++ + ++ +P Sbjct: 248 VLDVESDLKPNHEEVLATGAQRAELMQSWFEKIIEKLP 285 >3KHS-A nrPDB Length = 285 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 138/276 (50%), Positives = 191/276 (69%) Query: 7 YEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAG 66 Y+ K TA WL + RP + I+CGSGLG + D L + Y +IPNFP +V GHAG Sbjct: 4 YDLAKETAAWLNKQLQIRPVLGIVCGSGLGKIGDSLETSITVAYSDIPNFPVGSVKGHAG 63 Query: 67 RLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEV 126 L+FG +NG +CV M+GRFH+YEG+ + TFP+RVF LGV +V+TNAAGGLNP + Sbjct: 64 SLIFGSVNGVSCVCMKGRFHLYEGHTAARATFPMRVFKALGVKIVVLTNAAGGLNPSYRP 123 Query: 127 GDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRE 186 GD M++RDHINLPG +G NPL GPND+ G+RFP+M+ YD+T+R+ A+S +++G Sbjct: 124 GDFMVVRDHINLPGLAGANPLTGPNDDTEGERFPSMTSVYDKTLRKYAISAARELGMSYA 183 Query: 187 LQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVI 246 EG Y V GPSFET AEC++L+ +G+DAVGMST PE IVA+H G+R SLI+N + Sbjct: 184 THEGVYCCVNGPSFETPAECKILRLMGSDAVGMSTAPETIVAKHGGMRCLAVSLISNVIA 243 Query: 247 MDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + E+ + HEEVL AG++A+ ++ V +++ I Sbjct: 244 SNCETPAEPTHEEVLRAGEEASARMTALVKLVIEKI 279 >6BHB-A nrPDB Length = 287 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 127/279 (45%), Positives = 176/279 (63%) Query: 6 TYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHA 65 YE+ A+++ + P + IICGSGLG L +++ + ++ Y IPNFP++TV GH Sbjct: 8 NYENASMAADYIKRVSNVLPDIGIICGSGLGKLIEEIEERKVIPYINIPNFPKTTVAGHV 67 Query: 66 GRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFE 125 G LV G + GR V MQGR HMYEGY ++ P+RV LLGV L++TN AGG+N K + Sbjct: 68 GNLVLGSVGGRKIVAMQGRLHMYEGYSNQEIALPIRVMKLLGVRVLLITNLAGGINRKLK 127 Query: 126 VGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQR 185 GD +LI+ HIN PG N L GPN + FG RFP +S+AYDR ++Q AL ++ Q Sbjct: 128 SGDFVLIKGHINFPGLGLNNVLVGPNQDEFGPRFPDLSNAYDRLLQQLALKIAQENDFQD 187 Query: 186 ELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKV 245 + EG Y GP++E+ E +L KLG D VGMSTVPEVI+A HCG++V SLI N Sbjct: 188 LVHEGVYAFNGGPTYESPDESNMLLKLGCDVVGMSTVPEVIIACHCGIKVLAVSLIANNS 247 Query: 246 IMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL 284 I+D E+ NHE+VLA ++ A L+ + ++ +PL Sbjct: 248 ILDAENDVSINHEKVLAVAEKRADLLQMWFKEIITRLPL 286 >4LNA-A nrPDB Length = 293 Score = 339 bits (869), Expect = 9e-94, Method: Composition-based stats. Identities = 133/284 (46%), Positives = 180/284 (63%), Gaps = 9/284 (3%) Query: 2 ENGY---TYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPR 58 EN Y +E + T +++ S RP + II G+GLG LT++L Y IP+FP Sbjct: 16 ENLYFQSMFEQIQETTQFIQSKITLRPAIGIILGTGLGALTNELDIDTTIPYETIPHFPL 75 Query: 59 STVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAG 118 STV H+G+L+ G L G++ V+MQGRFH YEGY + +VT+PVRV H LG+ TL+V+NAAG Sbjct: 76 STVEFHSGKLLIGTLGGKSVVVMQGRFHYYEGYTMQQVTYPVRVMHALGIQTLLVSNAAG 135 Query: 119 GLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTW 178 G+NP F+ D+M+I DHI+L QNPL PN FGDRFP MS+ Y +++ A S Sbjct: 136 GMNPTFQTSDLMVIDDHISL--LLPQNPLICPNPPIFGDRFPDMSEPYRKSLIDLAFSVA 193 Query: 179 KQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGF 238 ++ L+ G YV V GP ET AE R+L++ GADAVGMSTVPEVIVA G+ VFG Sbjct: 194 AELDI--PLKRGVYVSVTGPQLETRAEYRMLRQWGADAVGMSTVPEVIVANQLGMDVFGI 251 Query: 239 SLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 S+IT+ D +LEKA ++LA QA KL + ++ + Sbjct: 252 SVITDLCFPD--TLEKAELVKILATAAQAEPKLTMLIREMIGRL 293 >4M1E-A nrPDB Length = 297 Score = 323 bits (827), Expect = 8e-89, Method: Composition-based stats. Identities = 125/275 (45%), Positives = 169/275 (61%), Gaps = 7/275 (2%) Query: 10 YKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLV 69 + + P V +I G+GLGGL +++ Q Y +IP+FP STV HAGRLV Sbjct: 30 IDQATAKISQLWQGEPAVGMILGTGLGGLAEQIEQDIAIPYSDIPHFPTSTVKSHAGRLV 89 Query: 70 FGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDI 129 G L G V M+GRFH YEGY L +VTFPVRV +GV TL+VTNAAGG+NP+ ++ D+ Sbjct: 90 CGRLRGIPIVAMEGRFHYYEGYSLEQVTFPVRVMKAMGVKTLLVTNAAGGINPQLDLSDV 149 Query: 130 MLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQE 189 ++I DHINL +NPLRGPNDE G RFP MS YD + A ++G + Sbjct: 150 LIIEDHINL---MPENPLRGPNDEELGPRFPDMSHPYDCQHMEVARQVALELGI--HCPK 204 Query: 190 GTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDY 249 G +V V+GP+ ET AE R+L+ +GAD VGMSTVPEV+VA H GLRV GFS++T+ + D Sbjct: 205 GVFVAVSGPNLETRAEYRMLKLMGADVVGMSTVPEVLVAVHAGLRVLGFSVVTDLCLPDA 264 Query: 250 ESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL 284 + N ++L + KL + + ++ I L Sbjct: 265 LEPVELN--KILEVAARGGAKLARLIPEILPRIAL 297 >3ODG-A nrPDB Length = 287 Score = 320 bits (820), Expect = 5e-88, Method: Composition-based stats. Identities = 111/274 (40%), Positives = 156/274 (56%), Gaps = 8/274 (2%) Query: 12 NTAEWLLS-HTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVF 70 +++ +PQ+A I GSGLG L D++T Y +IP FP S+V GHAG LV Sbjct: 20 QAVKYIQKIKPGFKPQIAFILGSGLGDLVDQITNDTTISYADIPGFPVSSVHGHAGELVL 79 Query: 71 GFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIM 130 G L G + M+GR H YEG + +T PVR F L+G + L TNAAG L P+ G ++ Sbjct: 80 GDLCGVPVMCMKGRGHFYEGKGMSIMTNPVRTFKLMGCEFLFCTNAAGSLRPEVLPGSVV 139 Query: 131 LIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEG 190 +++DHIN PL GPND+RFG RF ++++AYD+ +R +Q+ L EG Sbjct: 140 MLKDHIN---TMPGTPLVGPNDDRFGPRFFSLANAYDKDLRADMAKIAQQLDI--PLTEG 194 Query: 191 TYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYE 250 +V GP FET AE R++Q +G D VGMS VPEV+ A HCGL+V + ITN + + Sbjct: 195 VFVSYPGPCFETPAEIRMMQIIGGDVVGMSVVPEVLSAAHCGLKVIALTAITN--LAEGL 252 Query: 251 SLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL 284 S +HE+ L K A+ + + + S L Sbjct: 253 SDVVLSHEQTLKFAKVASVNFTKLIEAFLKSKAL 286 >3LA8-A nrPDB Length = 303 Score = 317 bits (813), Expect = 3e-87, Method: Composition-based stats. Identities = 125/273 (45%), Positives = 168/273 (61%), Gaps = 10/273 (3%) Query: 10 YKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLV 69 T ++L + +P+ +I GSGLG L +++ A + +Y +IPN+ RSTV GHAG+L+ Sbjct: 41 IYETRDFLTAKGVQKPEFGLILGSGLGELAEEIENALVLNYADIPNWGRSTVSGHAGKLI 100 Query: 70 FGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDI 129 +G L GR + +QGRFH YEG + VTFP+R+ LG L+VTNAAGG+ F G + Sbjct: 101 YGELAGRKVLALQGRFHYYEGNSMELVTFPIRIMKALGCQGLIVTNAAGGIG--FGPGTL 158 Query: 130 MLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQE 189 M I DHINL G NPL G N + FG RFP MS+AY R+ A ++G + L E Sbjct: 159 MAISDHINLTGA---NPLMGENLDDFGFRFPDMSNAYTADYREVAHQVADKIGIK--LDE 213 Query: 190 GTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDY 249 G Y+ V+GPS+ET AE R + LGADAVGMSTVPEVIVA H GL+V G S ITN Sbjct: 214 GVYIGVSGPSYETPAEIRAFKTLGADAVGMSTVPEVIVAVHSGLKVLGISAITNYAAGF- 272 Query: 250 ESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + NHEEV+A +Q + + V ++ + Sbjct: 273 --QSELNHEEVVAVTQQIKEDFKGLVKAILVEL 303 >5IFK-A nrPDB Length = 312 Score = 316 bits (811), Expect = 5e-87, Method: Composition-based stats. Identities = 128/273 (46%), Positives = 174/273 (63%), Gaps = 15/273 (5%) Query: 25 PQVAIICGSGLGGLTDKLTQ---AQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMM 81 P+ +ICGSGL G++ K+ I Y IP F STVPGH+G L+FG++NG V+M Sbjct: 34 PKALVICGSGLSGISTKIADEPKPLILSYSTIPGFKVSTVPGHSGELIFGYMNGAPVVLM 93 Query: 82 QGRFHMYEGYPLWKVTFPVRVFHLLG-VDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPG 140 GR H YEG+ L + P+R HLLG ++ L+VTNAAGG+N F+ GD+M + DHIN PG Sbjct: 94 NGRLHSYEGHSLAETVHPIRALHLLGSINVLIVTNAAGGINASFKAGDLMCVYDHINFPG 153 Query: 141 FSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSF 200 G +PLRG N + FG RF A SDAYD +R+ S K++ +R++ EGTY V GP+F Sbjct: 154 LCGFHPLRGANFDEFGPRFLATSDAYDLELRKLLFSKKKELNIERKIHEGTYSYVHGPTF 213 Query: 201 ETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLE------- 253 E+ AE R L+ G DAVGMSTVPEV+ ARHCG RV SLITN+ ++D + Sbjct: 214 ESRAESRFLRLAGTDAVGMSTVPEVVTARHCGWRVLALSLITNECVVDPPASAHDENPVP 273 Query: 254 ----KANHEEVLAAGKQAAQKLEQFVSILMASI 282 KA HEEVL +A++ +++ + ++A I Sbjct: 274 IQEGKATHEEVLENSAKASKDVQELIFSVVAEI 306 >4NS1-A nrPDB Length = 295 Score = 313 bits (802), Expect = 6e-86, Method: Composition-based stats. Identities = 123/275 (44%), Positives = 174/275 (63%), Gaps = 7/275 (2%) Query: 8 EDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGR 67 + Y A +L S + AII GSGLG L +K+ + Y EIP+F ++T GH G Sbjct: 28 QHYHEAASFLSSRLPGDAKTAIILGSGLGELAEKIENKTVIPYNEIPHFAQATAVGHKGN 87 Query: 68 LVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVG 127 ++ G L G V MQGRFH YEGY + +VTFP+RV LLG++ L V+NAAGG+N F+VG Sbjct: 88 IIGGILGGTPVVAMQGRFHYYEGYSMDQVTFPIRVMKLLGIENLFVSNAAGGINTSFKVG 147 Query: 128 DIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQREL 187 D+M+I DHIN + NPL GPN + FG RFP M+ AYDR +A +++ + Sbjct: 148 DLMIICDHIN----NLPNPLIGPNMDMFGVRFPDMTRAYDREFIAKAKGIAQELNI--PV 201 Query: 188 QEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIM 247 +EG YV + GPS+ET AE + ++G DA+GMSTVPEVIVARH G+RVFG S+ITN+ Sbjct: 202 KEGVYVGLTGPSYETPAEYKFWGQVGGDAIGMSTVPEVIVARHTGIRVFGMSVITNEGYH 261 Query: 248 DYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + + ++V+ A A++K+ + L+A++ Sbjct: 262 FADDFVN-DEQDVIRAANAASEKMGAIFARLIAAV 295 >1YQQ-A nrPDB Length = 277 Score = 307 bits (787), Expect = 3e-84, Method: Composition-based stats. Identities = 112/264 (42%), Positives = 148/264 (56%), Gaps = 7/264 (2%) Query: 20 HTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACV 79 P+VA I GSGLG L D++ A Y ++P FP STV GHAG LV G L G V Sbjct: 21 KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80 Query: 80 MMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLP 139 M+GR H YEG + +T +R F LLG + L TNAAG L P+ G ++ ++DHIN Sbjct: 81 CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN-- 138 Query: 140 GFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPS 199 P+ G ND+RFG+RF ++++AYD R K+ G L EG +V GP+ Sbjct: 139 -TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGPN 195 Query: 200 FETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEE 259 FET AE R++Q +G D VGMS VPEVI ARHC L+V S ITN + S K +H + Sbjct: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM--AEGLSDVKLSHAQ 253 Query: 260 VLAAGKQAAQKLEQFVSILMASIP 283 LAA + + Q + + I Sbjct: 254 TLAAAELSKQNFINLICGFLRKIA 277 >1VMK-A nrPDB Length = 277 Score = 295 bits (755), Expect = 2e-80, Method: Composition-based stats. Identities = 121/270 (44%), Positives = 170/270 (62%), Gaps = 12/270 (4%) Query: 11 KNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVF 70 + ++ T P + II GSG G +K+ I DY +IP+FP+ TV GH+G+LVF Sbjct: 18 EEARTFISERTNLSPDILIILGSGFGPFIEKVEDPVIIDYKDIPHFPQPTVEGHSGKLVF 77 Query: 71 GFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIM 130 G ++ + ++M GRFH+YEG+ V FPV + +GV +VVTNAAG +NP+F+ G+I+ Sbjct: 78 GRISDKPVMIMAGRFHLYEGHDPATVAFPVYLAKYVGVKGVVVTNAAGAINPEFKPGEII 137 Query: 131 LIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEG 190 L+RD IN F +NPLRGPNDE+ G RFP MS D +++ E+ L+EG Sbjct: 138 LVRDIIN---FMFRNPLRGPNDEKIGPRFPDMSSVVDPEW-------ARKIQERLSLKEG 187 Query: 191 TYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYE 250 Y+ V GPS+ET AE RV +KLGAD VGMSTVPEVI A+HCGL+V FS +TN Sbjct: 188 VYIGVLGPSYETPAEIRVFEKLGADLVGMSTVPEVIAAKHCGLKVVVFSCVTNM--AAGI 245 Query: 251 SLEKANHEEVLAAGKQAAQKLEQFVSILMA 280 + + +HEEV+ K A K+E+ ++ + Sbjct: 246 THGRLSHEEVVRTTKMAQGKIEKALTTAVE 275 >4UC0-A nrPDB Length = 291 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 106/281 (37%), Positives = 146/281 (51%), Gaps = 12/281 (4%) Query: 2 ENGYTYEDYKNTAEWLLSHTK-HRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 EN Y ++ + L+ P++AI+ GSGLGGL D++ A + +IP FP+ Sbjct: 16 ENLY-FQSMTPAVDLLIDRLNGLLPRIAIVLGSGLGGLVDEVENAVRIPFADIPGFPQGG 74 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 V GHA LV G G+ +M+ GR H YE + P+ LGV TL++TNAAG L Sbjct: 75 VSGHAKELVAGLFAGQPIIMLAGRVHYYEEGDAAAMRLPIETLASLGVTTLILTNAAGSL 134 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ 180 G +M + DHIN FSG NPL G + RF M+ AYD + + Sbjct: 135 RADMPPGSVMQLIDHIN---FSGHNPLIGETGD---GRFVGMTQAYDGELAEAMRRAAD- 187 Query: 181 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL 240 E L G Y+ +GPSFET AE R+ + LGADAVGMSTVPEVI+AR GL+V S+ Sbjct: 188 -AEDISLSSGVYMWFSGPSFETPAEIRMARTLGADAVGMSTVPEVILARFFGLKVAAASV 246 Query: 241 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMAS 281 ITN + + +HEE ++L + ++ Sbjct: 247 ITNYG--AGMTGAELSHEETKDMAPIGGRRLVAILKRMIVD 285 >2A8Y-A nrPDB Length = 270 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 63/281 (22%), Positives = 128/281 (45%), Gaps = 32/281 (11%) Query: 18 LSHTKHRPQVAIICGSGL--GGLTDKLTQAQIF-DYGEIPNFPRSTVPGHAGRLVFGFLN 74 + + + II GSGL G+ + + +++ YG+ +F + G + Sbjct: 1 MIEQNEKASIGIIGGSGLYDPGIFSESKEIKVYTPYGQPSDF-----------ITIGKIG 49 Query: 75 GRACVMM--QGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIM 130 ++ + GR H P K+ + ++ L LGV ++ +A G L +++GD + Sbjct: 50 NKSVAFLPRHGRGHRI---PPHKINYRANIWALKELGVRWVISVSAVGSLRMDYKLGDFV 106 Query: 131 LIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEG 190 + I++ + GP +M+D + ++R+ A+ T K++ + + G Sbjct: 107 IPDQFIDMTKNREYSFFDGPVVAHV-----SMADPFCNSLRKLAIETAKELNIKTH-ESG 160 Query: 191 TYVMVAGPSFETVAECRVLQKL-GADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDY 249 TY+ + GP F T AE R +++ AD +GM+ VPEV +A + +++T+ D Sbjct: 161 TYICIEGPRFSTRAESRTWREVYKADIIGMTLVPEVNLACEAQMCYATIAMVTDY---DV 217 Query: 250 ESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL-PDKAS 289 + EEV + +K ++ + L+ +P P++ S Sbjct: 218 FAEIPVTAEEVTRVMAENTEKAKKLLYALIQKLPEKPEEGS 258 >1V4N-A nrPDB Length = 281 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 67/284 (23%), Positives = 122/284 (42%), Gaps = 34/284 (11%) Query: 17 LLSHTKHRPQVAIICGSGL--GGLTDKLTQAQIF-DYGEIPNFPRSTVPGHAGRLVFGFL 73 ++ K + + II GSGL + + + +++ YGE + ++ G L Sbjct: 1 MMIEPKEKASIGIIGGSGLYDPQILTNVKEIKVYTPYGE-----------PSDNIILGEL 49 Query: 74 NGRACVMM--QGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDI 129 GR + GR H P K+ + ++ L LGV ++ +A G L ++ GD Sbjct: 50 EGRKVAFLPRHGRGHRI---PPHKINYRANIWALKSLGVKWVIAVSAVGSLRLDYKPGDF 106 Query: 130 MLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQE 189 ++ I++ GP +M+D + +R L + K +G + Sbjct: 107 VVPNQFIDMTKGRTYTFFDGPTVAHV-----SMADPFCEHLRSIILDSAKDLGITT-HDK 160 Query: 190 GTYVMVAGPSFETVAECRVLQKL-GADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMD 248 GTY+ + GP F T AE V +++ AD +GM+ VPEV +A + ++T+ D Sbjct: 161 GTYICIEGPRFSTRAESIVWKEVFKADIIGMTLVPEVNLACEAEMCYSVIGMVTDY---D 217 Query: 249 YESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPL-PD--KAS 289 + EEV + K+++ + ++ +P PD K S Sbjct: 218 VFADIPVTAEEVTKVMAENTAKVKKLLYEVIRRLPEKPDERKCS 261 >1WTA-A nrPDB Length = 275 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 65/282 (23%), Positives = 118/282 (41%), Gaps = 29/282 (10%) Query: 17 LLSHTKHRPQVAIICGSGL--GGLTDK-LTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFL 73 + R V +I GSGL G+ + + YG +F +V G + Sbjct: 4 ITRPPGVRAHVGVIGGSGLYDPGIVENPVEVKVSTPYGNPSDF-----------IVVGDV 52 Query: 74 NGRACVMM--QGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDI 129 G + GR H P + + ++ L LGV ++ +A G L + GD Sbjct: 53 AGVKVAFLPRHGRGHRI---PPHAINYRANIWALKALGVKWVISVSAVGSLREDYRPGDF 109 Query: 130 MLIRDHINLPGFSGQ-NPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQ 188 ++ I++ GP +M+D + +RQR + + +++G + Sbjct: 110 VVPDQFIDMTKNRRHYTFYDGPVTVHV-----SMADPFCEDLRQRLIDSGRRLGYTVH-E 163 Query: 189 EGTYVMVAGPSFETVAECRVLQKL-GADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIM 247 GTYV + GP F T AE RV + + AD +GM+ VPE+ +A L +++T+ + Sbjct: 164 RGTYVCIEGPRFSTRAESRVWKDVFKADIIGMTLVPEINLACEAQLCYATLAMVTDYDVW 223 Query: 248 DYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS 289 + E V+ + + A+++ V +A P ++ S Sbjct: 224 ADRPVTAEEVERVMISNVERARRMLYDVIPKLAGEPELERCS 265 >6DZ3-A nrPDB Length = 297 Score = 251 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 69/283 (24%), Positives = 123/283 (43%), Gaps = 20/283 (7%) Query: 2 ENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTV 61 EN Y T T ++ II G+GL ++ + + Y + P F + Sbjct: 8 ENLYFQSMASGT-------TTTAVKIGIIGGTGLDDP--EILEGRTEKYVDTP-FGKP-- 55 Query: 62 PGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLL--GVDTLVVTNAAGG 119 + L+ G + CV++ + P KV + ++ L G ++VT A G Sbjct: 56 ---SDALILGKIKNVDCVLLARHGRQHTIMP-SKVNYQANIWALKEEGCTHVIVTTACGS 111 Query: 120 LNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWK 179 L + + GDI++I I+ Q+ G + G M++ + R+ + T K Sbjct: 112 LREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAK 171 Query: 180 QMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFS 239 ++G R +GT V + GP F + AE + + GAD + M+TVPEV++A+ G+ + Sbjct: 172 KLGL-RCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIA 230 Query: 240 LITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 + T+ E E + + VL K+ A K + + + I Sbjct: 231 MATDYDCWK-EHEEAVSVDRVLKTLKENANKAKSLLLTTIPQI 272 >1G2O-A nrPDB Length = 268 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 99/276 (35%), Positives = 139/276 (50%), Gaps = 20/276 (7%) Query: 8 EDYKNTAEWLLSHTKH-RPQVAIICGSGLGGLTDKLTQAQ-IFDYGEIPNFPRSTVPGHA 65 E + A+ + T VA++ GSG L + E+P F T GHA Sbjct: 10 ELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHA 69 Query: 66 GRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFE 125 G L+ + +++ GR H YEG+ L V PVR G +V+TNAAGGL + Sbjct: 70 GELLSVPIGAHRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQ 129 Query: 126 VGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQR 185 VG +LI DH+NL ++PL G F ++DAY +R+ A + Q+ Sbjct: 130 VGQPVLISDHLNLT---ARSPL-------VGGEFVDLTDAYSPRLRELARQSDPQL---- 175 Query: 186 ELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKV 245 EG Y + GP +ET AE R+LQ LGAD VGMSTV E I AR G V G SL+TN Sbjct: 176 --AEGVYAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTN-- 231 Query: 246 IMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMAS 281 + + E +H EVLAAG +A ++ ++ ++A Sbjct: 232 LAAGITGEPLSHAEVLAAGAASATRMGALLADVIAR 267 >1C3X-A nrPDB Length = 266 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 88/257 (34%), Positives = 126/257 (49%), Gaps = 22/257 (8%) Query: 26 QVAIICGSGLGGLTDKLTQAQI-FDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGR 84 +A++ GSG GG + L + EIP F T + R+ + R +++ R Sbjct: 31 DMALVLGSGWGGAAELLGEVVAEVPTHEIPGFSSVT---RSIRVERADGSVRHALVLGSR 87 Query: 85 FHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ 144 H+YEG + V VR G +TL++TN GGLN ++ G +L+ DHINL + Sbjct: 88 THLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEWGAGTPVLLSDHINLT---AR 144 Query: 145 NPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVA 204 +PL GP F ++D Y +R+ A L EG Y GP +ET A Sbjct: 145 SPLEGPT-------FVDLTDVYSPRLRELAHRV------DPTLPEGVYAQFPGPHYETPA 191 Query: 205 ECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAG 264 E R+ LGAD VGMST E I ARHCGL V G SL+TN + S +H EV+ AG Sbjct: 192 EVRMAGILGADLVGMSTTLEAIAARHCGLEVLGVSLVTN--LAAGISPTPLSHAEVIEAG 249 Query: 265 KQAAQKLEQFVSILMAS 281 + A ++ ++ + Sbjct: 250 QAAGPRISALLADIAKR 266 >4L6I-A nrPDB Length = 320 Score = 211 bits (536), Expect = 3e-55, Method: Composition-based stats. Identities = 68/286 (23%), Positives = 115/286 (40%), Gaps = 37/286 (12%) Query: 19 SHTKHRPQVAIICGSGL--GGLTDKLTQAQIF-DYGEIPNFPRSTVPGHAGRLVFGFLNG 75 SH + +V II GSG L K+ Q+ +G+ + LV GF+ Sbjct: 19 SHMMSKVKVGIIGGSGFDDPNLFKKVGVRQVTTPFGK-----------PSDTLVEGFVGD 67 Query: 76 RACVMM--QGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIML 131 ACV++ G+ H+ P +V + V+ L LG ++ TNA G L GD ++ Sbjct: 68 VACVVLPRHGKGHLI---PPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVV 124 Query: 132 IRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTW----------KQM 181 + ++ D G M++ + RQ + K M Sbjct: 125 LNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTM 184 Query: 182 GEQRELQ-----EGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVF 236 + + EG+ V + GP F T E + + +G D V M+ VPEV +AR GL Sbjct: 185 DKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYA 244 Query: 237 GFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASI 282 +++T+ E E + VL +++ + + + +A I Sbjct: 245 SIAIVTDFDCWKSEE-EHVCVDMVLEQFRKSVVHVREILLEAVALI 289 >4GLJ-A nrPDB Length = 297 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 56/279 (20%), Positives = 109/279 (39%), Gaps = 25/279 (8%) Query: 12 NTAEWLLSHTKHRPQVAIICGSGL---GGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRL 68 T+ + K+ +AII GSGL LT+K + YGE + + Sbjct: 1 MTSTAVEITVKNAADIAIIGGSGLYQMQALTNKRSVKIETPYGE-----------PSDDI 49 Query: 69 VFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEV 126 V G LNG + + +V + ++ L LGV +V +A G L + Sbjct: 50 VLGELNGVTVAFLTRHGQGHR-LTPSEVPYRANIYALKTLGVRYIVSVSAVGSLQETLKP 108 Query: 127 GDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWK--QMGEQ 184 D+++ I++ +M+D + + + + + Sbjct: 109 LDMVIPDQMIDMTKQRVSTFFGDGAVAHV-----SMADPLCPEVADILIRAYDNADIADG 163 Query: 185 RELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNK 244 + + TYV + GP F T AE +++ AD +GM+ +PE +AR + +L+T+ Sbjct: 164 QCHAKATYVCIEGPQFSTRAESHWYRQMQADIIGMTNMPEAKLAREASIAYATLALVTDF 223 Query: 245 VIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIP 283 + + + + + + + A +Q + +A I Sbjct: 224 DCW-HPNEQAVSADYAIQNLMKNADNAQQVIKQAVALIA 261 >3OZB-A nrPDB Length = 259 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 61/256 (23%), Positives = 103/256 (40%), Gaps = 17/256 (6%) Query: 28 AIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHM 87 AII G+GL L + LT ++ + + P GR GR + + H Sbjct: 19 AIIGGTGLTQL-EGLTLSESLPIETP--YGAPSAPLQRGRY-----AGREVLFLARHGHP 70 Query: 88 YEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQN 145 + +P +V + ++ L G + ++ NA GG++ G + + I+ Sbjct: 71 HR-FPPHQVNYRANLWALKQAGAEAVIAVNAVGGIHAAMGTGHLCVPHQLIDYTSGREHT 129 Query: 146 PLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAE 205 G + F S YD +RQR + + +G G Y GP ETVAE Sbjct: 130 YFAGDIEHVTHIDF---SHPYDEPLRQRLIEALRALGLAHS-SHGVYACTQGPRLETVAE 185 Query: 206 CRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGK 265 L++ G D VGM+ +PE +AR L +L+ N +S E+ A Sbjct: 186 IARLERDGNDIVGMTGMPEAALARELDLPYACLALVVNP--AAGKSAGIITMAEIEQALH 243 Query: 266 QAAQKLEQFVSILMAS 281 K+ + ++ ++A Sbjct: 244 DGIGKVREVLARVLAG 259 >4JWT-A nrPDB Length = 259 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 37/186 (19%), Positives = 72/186 (38%), Gaps = 23/186 (12%) Query: 107 GVDTLVVTNAAGGLNPKFEVGDIML---IRDH-INLPGFSGQNPLRGPNDERFGDRFPAM 162 G L+ + AG ++ +VGD+++ + H +++ F G P F + Sbjct: 89 GATKLLFSGVAGAISTNLKVGDLIVATKLSQHDLDITAF-GHPYGYVPEGSVFVEA---- 143 Query: 163 SDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVL--QKLGADAVGMS 220 D+ M + + +MG+ +QEG G F E + GADA+ M Sbjct: 144 ----DKDMIELSKKVALEMGK--SVQEGIIAT--GDQFVANEERKNWIGTTFGADALEME 195 Query: 221 TVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMA 280 +V + F I++ MD + +E L + + + + + + Sbjct: 196 GGSVGVVCNALNIPFFILRSISDAADMD----ASFSFDEFLESSAKESAEFIMKMVDELV 251 Query: 281 SIPLPD 286 ++PL D Sbjct: 252 ALPLQD 257 >3QPB-A nrPDB Length = 282 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 42/235 (17%), Positives = 79/235 (33%), Gaps = 33/235 (14%) Query: 55 NFPRSTVPGHAGRLVF--GFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLV 112 +F + + + V G LNG + G + + L G DT + Sbjct: 63 HFDNAVLVADSREYVTYTGTLNGEKVSVTS------TGIGGPSASIAMEELKLCGADTFI 116 Query: 113 VTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQ 172 GG+ + GDI++ I + G + E FPA++ D + Sbjct: 117 RVGTCGGIELDVKGGDIVIATGAIRM---------EGTSKEYAPIEFPAVA---DLEVTN 164 Query: 173 RALSTWKQMGEQRELQEGTYVMVAG------P-----SFETVAECRVLQKLGADAVGMST 221 ++ K++G G P S+E + + ++LG A M + Sbjct: 165 ALVNAAKKLGYTS--HAGVVQCKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMES 222 Query: 222 VPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVS 276 + A H G+R L+ + ++ + AA + A + L + Sbjct: 223 AALFVAASHLGVRCGSDFLVVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIE 277 >1ODL-A nrPDB Length = 235 Score = 35.0 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 28/162 (17%), Positives = 51/162 (31%), Gaps = 13/162 (8%) Query: 106 LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDA 165 LG LV AG + G++++ G PL G + R + Sbjct: 80 LGARVLVRVGTAGAASSDLAPGELIV---------AQGAVPLDGTTRQYLEGR--PYAPV 128 Query: 166 YDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEV 225 D + + + +G + G T E R + G A M Sbjct: 129 PDPEVFRALWRRAEALGY--PHRVGLVASEDAFYATTPEEARAWARYGVLAFEMEASALF 186 Query: 226 IVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQA 267 ++ R G+R ++N++ + + E V + A Sbjct: 187 LLGRMRGVRTGAILAVSNRIGDPELAPPEVLQEGVRRMVEVA 228 >3MB8-A nrPDB Length = 279 Score = 34.3 bits (77), Expect = 0.065, Method: Composition-based stats. Identities = 34/188 (18%), Positives = 57/188 (30%), Gaps = 25/188 (13%) Query: 100 VRVFHLLGVDTLVVTNAAGGLNPK-FEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDR 158 + LG ++ G L PK + GD+ + +N G N G Sbjct: 80 IEELAYLGAKVIIRAGTCGSLKPKTLKQGDVCVTYAAVNETGLI-------SNILPEGFP 132 Query: 159 FPAMSDAYDRTMRQRALSTWKQMGEQRELQEGT---YVMVAGPSFETVAECRVLQKLGAD 215 A Y Q + K++G + G Y G ++ + K D Sbjct: 133 CVATPHVY-----QALMDAAKELGIEAASGIGVTQDYFYQNG---ILPSKLEMYSKC-CD 183 Query: 216 AVG--MSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQ 273 + MS V + AR G+ G + + E A + GK+ K+ Sbjct: 184 VIDMEMSGVLGLCQAR--GIATCGILAVDGSPLQWDEGDYDATGVKAT-TGKENMVKITL 240 Query: 274 FVSILMAS 281 + Sbjct: 241 KACANLRR 248 >4R31-A nrPDB Length = 279 Score = 33.9 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 56/156 (35%), Gaps = 19/156 (12%) Query: 2 ENGYTYEDYKNTAEWLLSHTKHR-PQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST 60 EN Y ++ L+ + ++A+I G ++++ Q + P F S+ Sbjct: 16 ENLY-FQSMSEVFHLGLTKAMLKGAKIAVIPGD--PARSERIAQRM-----DKPEFLASS 67 Query: 61 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL 120 + G+L V+ G V+ V LGV T + G + Sbjct: 68 REFTSW---LGYLENEPVVVCS------TGIGGPSVSICVEELAQLGVGTFLRIGTTGAI 118 Query: 121 NPKFEVGDIMLIRDHINLPGFSGQ-NPLRGPNDERF 155 P VGD+++ + L G S PL P F Sbjct: 119 QPYINVGDVLVTTGAVRLDGASRHFAPLEYPAVADF 154 >3TL6-A nrPDB Length = 242 Score = 33.1 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 30/174 (17%), Positives = 59/174 (33%), Gaps = 31/174 (17%) Query: 93 LWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPND 152 + +F+ GV ++ +AG + ++GDI+ I + N Sbjct: 76 PSIGIYAYELFNFYGVKRIIRIGSAGAFDESLKLGDIV-----IGMGACYDSNF------ 124 Query: 153 ERFGDRFPAMSDAY----DRTMRQRALSTWKQMGEQRE---LQEGTYVMVAGPSFETVAE 205 +R + Y D + + A+ +++G + + + Y G Sbjct: 125 ----ERQYDIPGKYSCIADFQLCREAVDAAEKLGYRYKVGNIYSANYFYDDGDH------ 174 Query: 206 CRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEE 259 +K+G AV M ++A + I++ Y S EK EE Sbjct: 175 SGAWKKMGVLAVEMEAAALYMIAARARKQALCMLTISDLC---YGSGEKMTAEE 225 >4WKO-A nrPDB Length = 245 Score = 32.3 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 27/176 (15%), Positives = 59/176 (33%), Gaps = 25/176 (14%) Query: 105 LLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHI--NLPGFSGQNPLRGPNDERFGDRFPAM 162 GV ++ + AG L ++ D+++ + ++ + +PL F Sbjct: 82 AFGVQKVLFSGVAGSLVKDLKINDLLVATQLVQHDVDLSAFDHPL----------GFIPE 131 Query: 163 SDAYDR---TMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAE--CRVLQKLGADAV 217 S + ++ A + + L+EG +G F E ++ + A AV Sbjct: 132 SAIFIETSGSLNALAKKIANE--QHIALKEGVIA--SGDQFVHSKERKEFLVSEFKASAV 187 Query: 218 GMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQ 273 M V + G+ I++ + + +E L + K + Sbjct: 188 EMEGASVAFVCQKFGVPCCVLRSISDNA----DEKAGMSFDEFLEKSAHTSAKFLK 239 >4U0O-B nrPDB Length = 296 Score = 31.9 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 41/218 (18%), Positives = 67/218 (30%), Gaps = 41/218 (18%) Query: 33 SGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQ-GRFHMYEGY 91 S + L + I + G PN A L+ G RAC Q + H Sbjct: 22 STVQRLVRQYGIHTICEEGRCPNRGECYGQKTATFLLLGPTCTRACAFCQVEKGHAPAAV 81 Query: 92 PLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIM----LIRDHINLPGFSGQNP- 146 + T LG+ +V+T+ A P G + IR +P Sbjct: 82 DPEEPTKIAAAVATLGLRYVVLTSVARDDLPDQGAGQFVATMAAIRQRCPGTEIEVLSPD 141 Query: 147 ---LRGPNDERFGDRFPAMSDA----------------------YDRTMRQRALSTWKQM 181 RG +R + Y+ ++R A T K++ Sbjct: 142 FRMDRGRLSQRDCIAQIVAAQPACYNHNLETVRRLQGPVRRGATYESSLRVLA--TVKEL 199 Query: 182 GEQRELQEGTYVMVAGPSFETVAEC----RVLQKLGAD 215 + G + + ET AE + L+++G D Sbjct: 200 NPDIPTKSGLMLGLG----ETEAEIIETLKDLRRVGCD 233 >6AYO-A nrPDB Length = 238 Score = 31.6 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 30/81 (37%), Gaps = 11/81 (13%) Query: 107 GVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAY 166 G L+ T AG NP+ E+GD+ + + + G F ++ + Sbjct: 77 GAQVLLFTGVAGAFNPELEIGDL------LYATKLAQYDLDITAFGHPLG--FVPGNEIF 128 Query: 167 ---DRTMRQRALSTWKQMGEQ 184 D + AL K++ + Sbjct: 129 IKTDEKLNNLALEVAKELNIK 149 >4C1L-A nrPDB Length = 262 Score = 30.8 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 7/134 (5%) Query: 151 NDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQ--RELQEGTYVMVAGP-SFETVAE-- 205 ND +FG+ F ++ R + + + + E + L+ G + P SF+ E Sbjct: 16 NDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKA 75 Query: 206 CRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGK 265 R +++ AD G+ TV EV+ RH L V +S I + ++ E + Sbjct: 76 LRWMREA-ADEYGLVTVTEVMDTRHVEL-VAKYSDILQIGARNSQNFELLKEVGKVENPV 133 Query: 266 QAAQKLEQFVSILM 279 + + + L+ Sbjct: 134 LLKRGMGNTIQELL 147 >3PNS-A nrPDB Length = 261 Score = 30.4 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 67/199 (33%), Gaps = 29/199 (14%) Query: 90 GYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ-NPLR 148 G P + V LGV T + G + P VGD+++ + L G S P+ Sbjct: 77 GGPSTSIA--VEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPME 134 Query: 149 GPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAG-PSFET----- 202 P F M+ A + + T+ G ++T Sbjct: 135 FPAVPDFDVA---------TAMKAAAQESGATVHMGVTASSDTF--YPGQERYDTFTGRV 183 Query: 203 ----VAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLI----TNKVIMDYESLEK 254 + Q +G M + + + GL+ + + T K I D+ +L++ Sbjct: 184 VRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKE 243 Query: 255 ANHEEVLAAGKQAAQKLEQ 273 + +AA+K+ + Sbjct: 244 -TEARSIKVVVEAARKMLK 261 >4M3N-A nrPDB Length = 254 Score = 30.4 bits (67), Expect = 0.91, Method: Composition-based stats. Identities = 27/195 (13%), Positives = 64/195 (32%), Gaps = 34/195 (17%) Query: 93 LWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIML-----IRDHINLPGFSGQNPL 147 + + G TL+ AG + + ++ D+++ IN F+GQN Sbjct: 89 PSASIYIHELVQFYGCKTLIRVGTAGAITERLKLRDLVIAQAACTDSSINNLRFAGQNY- 147 Query: 148 RGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECR 207 P F + AY++ + + G + + + Sbjct: 148 -APIA-----TFDLLRRAYEQAQSR-----------GMPVHVGNVLSTDTFYHDQPNPYQ 190 Query: 208 VLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQA 267 + + G AV M +A G++ I++ +I ++ ++ Sbjct: 191 LWAQFGVLAVEMEAAGLYTLAAKFGVQALCILTISDHLITGEKT-----------TPQER 239 Query: 268 AQKLEQFVSILMASI 282 + +Q + + + +I Sbjct: 240 QETFDQMIEVALETI 254 >2AMY-A nrPDB Length = 246 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 11 KNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST-VPGHAGRLV 69 K ++L + + ++ ++ GS + ++L + Y + FP + V G+L+ Sbjct: 26 KEMDDFLQ-KLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYV--FPENGLVAYKDGKLL 82 Query: 70 F 70 Sbjct: 83 C 83 >4TYM-A nrPDB Length = 258 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 43/118 (36%), Gaps = 18/118 (15%) Query: 71 GFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHL-LGVDTLVVTNAAGGLNPKFEVGDI 129 G G +M G + ++ R + GV TL+ AG +NP V ++ Sbjct: 72 GTYKGHRVSVMG------TGMGMPSISIYARELIVDYGVKTLIRVGTAGAINPDIHVREL 125 Query: 130 MLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQREL 187 +L + + N +R E FP ++ D + +A K+M + Sbjct: 126 VLAQ-----AAATNSNIIRNDWPE---FDFPQIA---DFKLLDKAYHIAKEMDITTHV 172 >4YML-A nrPDB Length = 245 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 18/26 (69%) Query: 109 DTLVVTNAAGGLNPKFEVGDIMLIRD 134 D ++ T +AGGL P +VGDI++ + Sbjct: 69 DVIINTGSAGGLAPTLKVGDIVVSDE 94 >6CFS-A nrPDB Length = 262 Score = 28.9 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 25/59 (42%), Gaps = 2/59 (3%) Query: 12 NTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQ-AQIFDYGEIPNFPRSTVPGHAGRLV 69 A +L + R Q+ ++ GS + ++L ++ + + TV GRL+ Sbjct: 34 EVAAFLQ-KLRSRVQIGVVGGSDYCKIAEQLGDGDEVIEKFDYVFAENGTVQYKHGRLL 91 >4G89-A nrPDB Length = 237 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 39/120 (32%), Gaps = 38/120 (31%) Query: 26 QVAIICG--SGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQG 83 ++ II + L DK+ Q G + G L+G +++ Sbjct: 7 KIGIIGAMEEEVTLLRDKIENRQTITIG-------------GSEIYTGQLHGVDVALLKS 53 Query: 84 RFHMYEGYPLWKVTFPVRVFHLLGVDTL---------VVTNAAGGLNPKFEVGDIMLIRD 134 +V +G L + T +AGGL +VGDI++ + Sbjct: 54 GI--------------GKVAAAMGATLLLERCQPDVIINTGSAGGLASTLKVGDIVVSDE 99 >4MPH-A nrPDB Length = 192 Score = 28.5 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 22/52 (42%), Gaps = 1/52 (1%) Query: 113 VTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSD 164 V N GL ++ D+++ + G ++ LR E +R +++ Sbjct: 13 VVNKEYGLPEDYKPEDLVVPNVPFSFSGTLEKSYLRKEAAEAL-ERLFDLAN 63 >3UAY-A nrPDB Length = 235 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 49/153 (32%), Gaps = 23/153 (15%) Query: 107 GVDTLVVTNAAGGLNPKFEVGDIML-----IRDHINLPGFSGQNPLRGPNDERFGDRFPA 161 GV L+ G + +V D+++ ++N F G + N F Sbjct: 81 GVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAAN-------FDL 133 Query: 162 MSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMST 221 + AYD + + L + E++ + L G AV M T Sbjct: 134 LKKAYDAGTEKGLH-----VRVGNVLTADVFYR------ESMDMVKKLGDYGVLAVEMET 182 Query: 222 VPEVIVARHCGLRVFGFSLITNKVIMDYESLEK 254 +A G+ ++N + E+ + Sbjct: 183 TALYTLAAKYGVNALSVLTVSNHIFTGEETTSE 215 >1WG8-A nrPDB Length = 285 Score = 28.1 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 39/123 (31%), Gaps = 14/123 (11%) Query: 65 AGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFP--VRVFHLLGVDTLVVTNAAGGLNP 122 G V G V H+ G + + F R LGV+ + G+ Sbjct: 43 RGGRVIGLDQDPEAVARAKGLHL-PGLTVVQGNFRHLKRHLAALGVERV------DGILA 95 Query: 123 KFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMG 182 V H++ P GP D R G P + +R + +++G Sbjct: 96 DLGVSSF-----HLDDPSRGFSYQKEGPLDMRMGLEGPTAKEVVNRLPLEALARLLRELG 150 Query: 183 EQR 185 E+ Sbjct: 151 EEP 153 >4XEU-A nrPDB Length = 673 Score = 28.1 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Query: 214 ADAVGMSTVPEVIVAR-----HCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAA 268 A+AVGM+ +V+ A+ H + + ++ + + +M+ S E A+ L K A Sbjct: 129 ANAVGMALAEKVLAAQFNRDGHAVVDHYTYAFLGDGCMMEGISHEVASLAGTLRLNKLIA 188 >4JPF-A nrPDB Length = 436 Score = 28.1 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 2/53 (3%) Query: 23 HRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRS-TVPGHAGRLVFGFLN 74 +R ++ + GSG+GGLT+ + + + P VPG +V GFL+ Sbjct: 119 NRERIGVSMGSGIGGLTN-IENNCRSLFEQGPRRISPFFVPGSIINMVSGFLS 170 >4R2W-A nrPDB Length = 252 Score = 27.7 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 90 GYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQ-NPLR 148 G P + V LGV+T + G + P VGD+++ + + L G S P+ Sbjct: 68 GGPSTSIA--VEELAQLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPME 125 Query: 149 GPNDERF 155 P F Sbjct: 126 FPAVANF 132 >1XAI-A nrPDB Length = 354 Score = 26.9 bits (58), Expect = 9.3, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 18/36 (50%) Query: 2 ENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGG 37 E T+E Y+ T E++LSH R I G G G Sbjct: 68 EKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATG 103 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.135 0.362 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,038,294 Number of Sequences: 36641 Number of extensions: 425559 Number of successful extensions: 1334 Number of sequences better than 10.0: 52 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 1172 Number of HSP's gapped (non-prelim): 88 length of query: 289 length of database: 10,336,785 effective HSP length: 96 effective length of query: 193 effective length of database: 6,819,249 effective search space: 1316115057 effective search space used: 1316115057 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)