BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00401 (534 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6HU9-a nrPDB 1065 0.0 3ASN-A nrPDB 597 e-171 5Z62-A nrPDB 586 e-168 3HB3-A nrPDB 570 e-163 3FYE-A nrPDB 567 e-162 6HWH-V nrPDB 362 e-100 2YEV-A nrPDB 355 3e-98 6ADQ-F nrPDB 350 7e-97 1FFT-A nrPDB 343 8e-95 3EH4-A nrPDB 75 8e-14 6IBW-A nrPDB 32 0.91 3HM6-X nrPDB 31 1.1 >6HU9-a nrPDB Length = 534 Score = 1065 bits (2753), Expect = 0.0, Method: Compositional matrix adjust. Identities = 534/534 (100%), Positives = 534/534 (100%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE Sbjct: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 Query: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH Sbjct: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180 Query: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG 240 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG Sbjct: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG 240 Query: 241 HPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD 300 HPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD Sbjct: 241 HPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD 300 Query: 301 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN 360 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN Sbjct: 301 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN 360 Query: 361 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG 420 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG Sbjct: 361 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG 420 Query: 421 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL 480 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL Sbjct: 421 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL 480 Query: 481 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS 534 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS Sbjct: 481 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS 534 >3ASN-A nrPDB Length = 514 Score = 597 bits (1540), Expect = e-171, Method: Compositional matrix adjust. Identities = 301/530 (56%), Positives = 402/530 (75%), Gaps = 25/530 (4%) Query: 2 VQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVG 61 + RWL+STN KDI LY + ++GM GTA+SL+IR EL PG+ L G+ Q++NV+V Sbjct: 3 INRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGT--LLGDDQIYNVVVTA 60 Query: 62 HAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVES 121 HA +MIFF+VMP +IGGFGN+L+PLMIGA D AFPR+NN++FW+LP + L+ S++VE+ Sbjct: 61 HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA 120 Query: 122 GAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHK 181 GAGTGWTVYPPL+ AH+G SVDL IF+LHL +SS+LGAINFI T +NM+ M+ ++ Sbjct: 121 GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ 180 Query: 182 LPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGH 241 PLFVWS+ ITA LLLLSLPVL+AGITMLL DRN NT+FF+ +GGGDPILY+HLFWFFGH Sbjct: 181 TPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH 240 Query: 242 PEVYILIIPGFGIISHVVSTYS-KKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD 300 PEVYILI+PGFG+ISH+V+ YS KK FG + MV+AM SIG LGF+VW+HHM+ VG+D D Sbjct: 241 PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD 300 Query: 301 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN 360 TRAYFTSATMIIAIPTG+K+FSWLAT+HGG+I+ + M++A+ F+FLFT+GGLTG+ LAN Sbjct: 301 TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLAN 360 Query: 361 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG 420 +SLD+ HDTYYVV HFHYVLSMGA+F++ G+ +W P G N+ A+I F ++F+G Sbjct: 361 SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVG 420 Query: 421 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL 480 N+ FFP HFLG++GMPRR DYPDA+ WN ++S+GSFI+ ++ L ++I+++ Sbjct: 421 VNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEA----- 475 Query: 481 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTP 530 F + ++ + ++++E+L PP H+F P Sbjct: 476 ----------------FASKREVLTVD-LTTTNLEWLNGCPPPYHTFEEP 508 >5Z62-A nrPDB Length = 513 Score = 586 bits (1511), Expect = e-168, Method: Compositional matrix adjust. Identities = 301/529 (56%), Positives = 398/529 (75%), Gaps = 25/529 (4%) Query: 3 QRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGH 62 RWL+STN KDI LY + ++G+ GTA+SL+IR EL PG+ L GN ++NV+V H Sbjct: 4 DRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAH 61 Query: 63 AVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESG 122 A +MIFF+VMP +IGGFGN+L+PLMIGA D AFPR+NN++FW+LP L+ L+ S +VE+G Sbjct: 62 AFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAG 121 Query: 123 AGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKL 182 AGTGWTVYPPL+ +H G SVDL IF+LHL +SS+LGAINFI T +NM+ MT ++ Sbjct: 122 AGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQT 181 Query: 183 PLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHP 242 PLFVWS+ ITA LLLLSLPVL+AGITMLL DRN NT+FF+ +GGGDPILY+HLFWFFGHP Sbjct: 182 PLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHP 241 Query: 243 EVYILIIPGFGIISHVVSTYS-KKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADT 301 EVYILI+PGFG+ISH+V+ YS KK FG + MV+AM SIG LGF+VW+HHM+ VG+D DT Sbjct: 242 EVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDT 301 Query: 302 RAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANA 361 RAYFTSATMIIAIPTG+K+FSWLAT+HG +++ + +L+A+ F+FLFT+GGLTG+ LAN+ Sbjct: 302 RAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLANS 361 Query: 362 SLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIGA 421 SLD+ HDTYYVV HFHYVLSMGA+F++ G+ +W P G ++ A+I F ++FIG Sbjct: 362 SLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGV 421 Query: 422 NVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGLN 481 N+ FFP HFLG++GMPRR DYPDA+ WN ++S+GSFI+ ++ L I+++++ Sbjct: 422 NLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAF----- 476 Query: 482 NKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTP 530 + + V+ + P S ++E+L PP H+F P Sbjct: 477 --ASKRKVLMVEEP---------------SMNLEWLYGCPPPYHTFEEP 508 >3HB3-A nrPDB Length = 558 Score = 570 bits (1469), Expect = e-163, Method: Compositional matrix adjust. Identities = 291/546 (53%), Positives = 378/546 (69%), Gaps = 41/546 (7%) Query: 4 RWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQY--LHG----------- 50 RW STN KDI +LY A G+ ++ +R+EL PG QY L G Sbjct: 21 RWFMSTNHKDIGILYLFTAGIVGLISVCFTVYMRMELQHPGVQYMCLEGARLIADASAEC 80 Query: 51 --NSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPM 108 N L+NV++ H VLM+FF+V+PAL GGFGNY +PL IGA D AFPR+NN+++W+ Sbjct: 81 TPNGHLWNVMITYHGVLMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLNNLSYWMYVC 140 Query: 109 GLVCLVTSTLV-----ESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAI 163 G+ V S L + G+G GW +YPPLS+ +A G S+DLAIFA+H++ SS+LGAI Sbjct: 141 GVALGVASLLAPGGNDQMGSGVGWVLYPPLSTTEA--GYSMDLAIFAVHVSGASSILGAI 198 Query: 164 NFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEV 223 N I T LNMR GMT+ K+PLF WS+FITA+L+LLSLPVL+ ITMLL+DRNF T FF+ Sbjct: 199 NIITTFLNMRAPGMTLFKVPLFAWSVFITAWLILLSLPVLAGAITMLLMDRNFGTQFFDP 258 Query: 224 SGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLL 283 +GGGDP+LY+H+ WFFGHPEVYI+I+PGFGIISHV+ST++KKP+FG + MV AMA+IG+L Sbjct: 259 AGGGDPVLYQHILWFFGHPEVYIIILPGFGIISHVISTFAKKPIFGYLPMVLAMAAIGIL 318 Query: 284 GFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIA 343 GF+VW+HHMY G+ +AYF ATM IA+PTGIK+FSW+AT+ GGSI TPML+A Sbjct: 319 GFVVWAHHMYTAGMSLTQQAYFMLATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLWAFG 378 Query: 344 FLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGL 403 FLFLFT+GG+TGV L+ A LD +HDTYYVV HFHYV+S+GA+F +FAG YYW ++ G Sbjct: 379 FLFLFTVGGVTGVVLSQAPLDRVYHDTYYVVAHFHYVMSLGAVFGIFAGVYYWIGKMSGR 438 Query: 404 NYNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATL 463 Y E Q+ FW++FIG+N+IFFP HFLG GMPRR DYP FA WN ++SIG++I+ Sbjct: 439 QYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDYPVEFAYWNNISSIGAYISFA 498 Query: 464 SLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPA 523 S FI I++ L G V N +N+ D ++E+ L SPP Sbjct: 499 SFLFFIGIVFYTLFAGKRVNVPNY---WNEHAD----------------TLEWTLPSPPP 539 Query: 524 VHSFNT 529 H+F T Sbjct: 540 EHTFET 545 >3FYE-A nrPDB Length = 566 Score = 567 bits (1461), Expect = e-162, Method: Compositional matrix adjust. Identities = 285/555 (51%), Positives = 382/555 (68%), Gaps = 51/555 (9%) Query: 4 RWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHG------------- 50 RW STN KDI VLY G+ A ++ +R+EL APG Q++ Sbjct: 19 RWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQ 78 Query: 51 ------------NSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRI 98 N L+NV++ GH +LM+FF+V+PAL GGFGNY +PL IGA D AFPR+ Sbjct: 79 SLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRM 138 Query: 99 NNIAFWVLPMGLVCLVTSTLV-----ESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHL 153 NN+++W+ G V S + G+G GW +YPPLS+ + SG S DLAIFA+HL Sbjct: 139 NNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLST--SESGYSTDLAIFAVHL 196 Query: 154 TSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLD 213 + SS+LGAIN I T LNMR GMTMHK+PLF WSIF+TA+L+LL+LPVL+ ITMLL D Sbjct: 197 SGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTD 256 Query: 214 RNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISM 273 RNF T+FF+ SGGGDP+LY+H+ WFFGHPEVYI+++P FGI+SHV++T++KKP+FG + M Sbjct: 257 RNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPM 316 Query: 274 VYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIR 333 VYAM +IG+LGF+VW+HHMY GL ++YF ATM+IA+PTGIKIFSW+AT+ GGSI Sbjct: 317 VYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIE 376 Query: 334 LATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGY 393 L TPML+A+ FLFLFT+GG+TG+ L+ AS+D +HDTYYVV HFHYV+S+GA+F +FAG Sbjct: 377 LKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGI 436 Query: 394 YYWSPQILGLNYNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYV 453 Y+W ++ G Y E ++ FW++F+GAN+ FFP HFLG GMPRR DYP+AFA WN+V Sbjct: 437 YFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFV 496 Query: 454 ASIGSFIATLSLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSS 513 +S+G+F++ S F+ +++ L G NN +N+ D + Sbjct: 497 SSLGAFLSFASFLFFLGVIFYTLTRGARVTANN---YWNEHAD----------------T 537 Query: 514 IEFLLTSPPAVHSFN 528 +E+ LTSPP H+F Sbjct: 538 LEWTLTSPPPEHTFE 552 >6HWH-V nrPDB Length = 583 Score = 362 bits (929), Expect = e-100, Method: Compositional matrix adjust. Identities = 204/531 (38%), Positives = 308/531 (58%), Gaps = 30/531 (5%) Query: 8 STNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMI 67 +T+ K I ++Y + G M+L++R ELA PG Q+L +++ +N L H +M+ Sbjct: 34 TTDHKLIGMMYVVACFIFFFIGGLMALLLRTELAVPGLQFL--SNEQYNQLFTMHGTVML 91 Query: 68 FFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESG-AGTG 126 F P ++ GF N ++PL IGA D AFPR+N ++FW+ G + L G A G Sbjct: 92 LFYATP-IVFGFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGGFLAPGGPADFG 150 Query: 127 WTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFV 186 WT Y PLS+ G DL IF L + + ++LGA+N I T + MR GM M ++P+F Sbjct: 151 WTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAPGMIMFRMPIFT 210 Query: 187 WSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYI 246 W+I +T+ ++L++ P+L++ + L DRN F+ + GG +L+EHLFWFFGHPEVYI Sbjct: 211 WNILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANGGT-MLWEHLFWFFGHPEVYI 269 Query: 247 LIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFT 306 + +P FGI++ + +S+KPVFG ++VYA SIG L VW+HH+Y G A +F+ Sbjct: 270 IALPFFGIVTEIFPVFSRKPVFGYTTLVYATISIGALSIAVWAHHLYATG--AVLLPFFS 327 Query: 307 SATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANASLDVA 366 T +IA+PTGIK +W+ T+ G + TPML+++ FL F +GGLTGV LA+ LD Sbjct: 328 FMTFMIAVPTGIKFVNWIGTMWKGQLTFETPMLFSVGFLVTFLLGGLTGVILASPPLDFH 387 Query: 367 FHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIGANVIFF 426 D+Y+VV HFHYVL +F+ +AG Y+W P++ G +++L ++ FWL IG + F Sbjct: 388 VTDSYFVVAHFHYVLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFWLTLIGFHTTFL 447 Query: 427 PMHFLGINGMPRRIPDY--PDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGLNNKV 484 H+LG GMPRR DY D F N V++IGSFI +S+ F++ ++ G V Sbjct: 448 VHHWLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPFVWNVFKSWRYGEPVTV 507 Query: 485 NNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNT-PAVQS 534 ++ N S+E+ + PP H+F P ++S Sbjct: 508 DDPWGYGN--------------------SLEWATSCPPPRHNFTELPRIRS 538 >2YEV-A nrPDB Length = 791 Score = 355 bits (911), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 205/527 (38%), Positives = 313/527 (59%), Gaps = 31/527 (5%) Query: 6 LYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVL 65 L + + K I ++Y A F+ SL+IR +LA P +Q+L G +N ++ H Sbjct: 19 LTTVDHKKIGLMYTATAFFAFALAGVFSLLIRTQLAVPNNQFLTGEQ--YNQILTLHGAT 76 Query: 66 MIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGA-G 124 M+FF ++ A + GFGN+++PLM+GA D A PR+N ++W +V + S GA Sbjct: 77 MLFFFIIQAGLTGFGNFVVPLMLGARDVALPRVNAFSYWAFLGAIVLALMSYFFPGGAPS 136 Query: 125 TGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPL 184 GWT Y P S+ Q+ SG VD + A+ L SSLLG NF+ T N+R GM++ K+P+ Sbjct: 137 VGWTFYYPFSA-QSESG--VDFYLAAILLLGFSSLLGNANFVATIYNLRAQGMSLWKMPI 193 Query: 185 FVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEV 244 +VWS+F + L L SL L+A ++LL+R S+F + GGDP+L++ FWF+ HP V Sbjct: 194 YVWSVFAASVLNLFSLAGLTAATLLVLLERKIGLSWFNPAVGGDPVLFQQFFWFYSHPTV 253 Query: 245 YILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADTRAY 304 Y++++P GI++ V ST+++KP+FG MV+A I +LG +VW+HHM+ VG + Sbjct: 254 YVMLLPYLGILAEVASTFARKPLFGYRQMVWAQMGIVVLGTMVWAHHMFTVGESTLFQIA 313 Query: 305 FTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANASLD 364 F T +IA+PTG+K+F+ + T+ GG +++ TP+ + + F+F F +GG+TGV L+ LD Sbjct: 314 FAFFTALIAVPTGVKLFNIIGTLWGGKLQMKTPLYWVLGFIFNFLLGGITGVMLSMTPLD 373 Query: 365 VAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIGANVI 424 FHD+Y+VV HFH VL G+ F FAG YYW P++ G Y+E+L ++ FWL +G + Sbjct: 374 YQFHDSYFVVAHFHNVLMAGSGFGAFAGLYYWWPKMTGRMYDERLGRLHFWLFLVGYLLT 433 Query: 425 FFPMHFLGINGMPRRIPDYPDAFAGW---NYVASIGSFIATLSLFLFIYILYDQLVNGLN 481 F P + LG GMPRR Y AGW N +++IG++I L ++IY ++ L +G Sbjct: 434 FLPQYALGYLGMPRRYYTYNADIAGWPELNLLSTIGAYILGLGGLVWIYTMWKSLRSG-- 491 Query: 482 NKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFN 528 KAPD N ++E+L SPP H+F+ Sbjct: 492 ----------PKAPD----------NPWGGYTLEWLTASPPKAHNFD 518 >6ADQ-F nrPDB Length = 575 Score = 350 bits (899), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 198/538 (36%), Positives = 313/538 (58%), Gaps = 30/538 (5%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 ++ + + +T+ K I ++Y ++ + G M+L +R ELA PG Q+L +++ FN L Sbjct: 27 LIYKLITTTDHKLIGIMYCVVCFAFFLVGGLMALFMRTELAMPGLQFL--SNEQFNQLFT 84 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 H +M+ F P ++ GF N +LPL IGA D AFPR+N ++FW+ G + + + Sbjct: 85 MHGTVMLLFYATP-IVFGFANLVLPLQIGAPDVAFPRLNALSFWLFLFGALIAIAGFITP 143 Query: 121 SGAGT-GWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTM 179 GA GWT Y PL+ G DL I L + + ++LG +N I T + MR GMTM Sbjct: 144 GGAADFGWTAYSPLTDAIHSPGAGGDLWIMGLAVGGLGTILGGVNMITTVVCMRAPGMTM 203 Query: 180 HKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFF 239 ++P+F W+I +T+ L+L++ P+L+A + L DR+ ++ + GG +L++HLFWFF Sbjct: 204 FRMPIFTWNILVTSILVLIAFPILTAALFGLAADRHLGAHIYDPANGGV-LLWQHLFWFF 262 Query: 240 GHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDA 299 GHPEVYI+ +P FGI+S + +S+KP+FG +++YA +I L VW+HHMY G A Sbjct: 263 GHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLAIAALSVAVWAHHMYATG--A 320 Query: 300 DTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALA 359 +F+ T +IA+PTGIK F+W+ T+ G + TPML+++ FL F +GGL+GV LA Sbjct: 321 VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFLITFLLGGLSGVLLA 380 Query: 360 NASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFI 419 + LD D+Y+V+ HFHYVL +F+ +AG Y+W P++ G +E+L ++ FWL FI Sbjct: 381 SPPLDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFI 440 Query: 420 GANVIFFPMHFLGINGMPRRIPDY--PDAFAGWNYVASIGSFIATLSLFLFIYILYDQLV 477 G + F H+LG GMPRR DY D F N ++++G+FI +S+ F++ ++ Sbjct: 441 GFHTTFLVQHWLGDEGMPRRYADYLPTDGFTTLNVISTVGAFILGVSMLPFVWNVFKSWR 500 Query: 478 NGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNT-PAVQS 534 G V++ N S+E+ + PP H+F P ++S Sbjct: 501 YGEPVTVDDPWGYGN--------------------SLEWATSCPPPRHNFTELPRIRS 538 >1FFT-A nrPDB Length = 663 Score = 343 bits (881), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 191/487 (39%), Positives = 284/487 (58%), Gaps = 11/487 (2%) Query: 3 QRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLE--LAAPGSQYL---HGNSQLFNV 57 + WL S + K + ++Y ++AI + G A ++++R + LA+ G H Q+F Sbjct: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFT- 104 Query: 58 LVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTST 117 H V+MIFF+ MP +IG N ++PL IGA D AFP +NN++FW +G++ + S Sbjct: 105 ---AHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL 160 Query: 118 LVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGM 177 V A TGW YPPLS I+ G VD I++L L+ I + L INF VT L MR GM Sbjct: 161 GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGM 220 Query: 178 TMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFW 237 TM K+P+F W+ L++ S P+L+ + +L LDR T FF GG+ ++Y +L W Sbjct: 221 TMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIW 280 Query: 238 FFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGL 297 +GHPEVYILI+P FG+ S + +T+S+K +FG S+V+A I +L F+VW HH + +G Sbjct: 281 AWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGA 340 Query: 298 DADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVA 357 A+ A+F TMIIAIPTG+KIF+WL T++ G I + ML+ I F+ F++GG+TGV Sbjct: 341 GANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVL 400 Query: 358 LANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLI 417 LA D H++ +++ HFH V+ G +F FAG YW P+ G NE + FW Sbjct: 401 LAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFW 460 Query: 418 FIGANVIFFPMHFLGINGMPRRIPDYPD-AFAGWNYVASIGSFIATLSLFLFIYILYDQL 476 IG V F P++ LG GM RR+ D F +A+ G+ + L + + +Y + Sbjct: 461 IIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSI 520 Query: 477 VNGLNNK 483 + N+ Sbjct: 521 RDRDQNR 527 >3EH4-A nrPDB Length = 618 Score = 74.7 bits (182), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 77/291 (26%), Positives = 132/291 (45%), Gaps = 42/291 (14%) Query: 221 FEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASI 280 F + G DP++ LFW+ GHP VY ++P + II ++ + + + A Sbjct: 269 FGLVEGVDPLVARTLFWWTGHPIVYFWLLPAYAIIYTILPKQAGGRLVSDPMARLAFLLF 328 Query: 281 GLLGFLVWSHHMYI-VGLDADTRAYFTSATMIIAIPT-------------------GIKI 320 LL V HH + G+D + + T+ +A+P+ G + Sbjct: 329 LLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGL 388 Query: 321 FSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYV 380 F W+ + + P+L + F+ GG G+ A+ +LD H+T +V GHFH Sbjct: 389 FGWIRALPWDNPAFVAPVLGLLGFI----PGGAGGIVNASFTLDYVVHNTAWVPGHFH-- 442 Query: 381 LSMGAIFSLFA-GYYYW-SPQILGL---NYNEKLAQIQFWLIFIGANVIFFPMHFLGING 435 L + ++ +L A G YW P + G + +L WL F+G ++ +H+ G+ Sbjct: 443 LQVASLVTLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLN 502 Query: 436 MPRR--IPDYPDAFAG------WNYVASIGSFIATLSLFLFIYILYDQLVN 478 +PRR I PDA+ +N +A I + ++L LFIY L+ L++ Sbjct: 503 VPRRAYIAQVPDAYPHAAVPMVFNVLAGI---VLLVALLLFIYGLFSVLLS 550 >6IBW-A nrPDB Length = 245 Score = 31.6 bits (70), Expect = 0.91, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 221 FEVSGGGD-PILYEHLFWFFGHPEVYILIIPGFGIISHVV 259 F V+ GD P + ++FFG EV + PG G++S +V Sbjct: 51 FTVAKQGDAPTIDTDFYFFFGKAEVVMKAAPGTGVVSSIV 90 >3HM6-X nrPDB Length = 644 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 446 AFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGLNN 482 A WNY +G+ +A L+ +I YDQ++ L Sbjct: 581 AELSWNYSGDLGARVALHELYKYINKYYDQIITALEE 617 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6HU9-a nrPDB 635 0.0 3HB3-A nrPDB 616 e-177 3FYE-A nrPDB 598 e-171 6HWH-V nrPDB 588 e-168 6ADQ-F nrPDB 583 e-167 3ASN-A nrPDB 578 e-165 5Z62-A nrPDB 577 e-165 1FFT-A nrPDB 541 e-154 2YEV-A nrPDB 504 e-143 3EH4-A nrPDB 211 8e-55 Sequences not found previously or not previously below threshold: 3MK7-A nrPDB 64 1e-10 4XYD-A nrPDB 45 6e-05 5GUW-B nrPDB 33 0.24 3AYF-A nrPDB 31 1.4 2XZ4-A nrPDB 30 3.6 5W8S-A nrPDB 29 4.4 >6HU9-a nrPDB Length = 534 Score = 635 bits (1639), Expect = 0.0, Method: Composition-based stats. Identities = 534/534 (100%), Positives = 534/534 (100%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE Sbjct: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 Query: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH Sbjct: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180 Query: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG 240 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG Sbjct: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG 240 Query: 241 HPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD 300 HPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD Sbjct: 241 HPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDAD 300 Query: 301 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN 360 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN Sbjct: 301 TRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALAN 360 Query: 361 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG 420 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG Sbjct: 361 ASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIG 420 Query: 421 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL 480 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL Sbjct: 421 ANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL 480 Query: 481 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS 534 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS Sbjct: 481 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS 534 >3HB3-A nrPDB Length = 558 Score = 616 bits (1589), Expect = e-177, Method: Composition-based stats. Identities = 289/546 (52%), Positives = 376/546 (68%), Gaps = 41/546 (7%) Query: 4 RWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLH-------------- 49 RW STN KDI +LY A G+ ++ +R+EL PG QY+ Sbjct: 21 RWFMSTNHKDIGILYLFTAGIVGLISVCFTVYMRMELQHPGVQYMCLEGARLIADASAEC 80 Query: 50 -GNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPM 108 N L+NV++ H VLM+FF+V+PAL GGFGNY +PL IGA D AFPR+NN+++W+ Sbjct: 81 TPNGHLWNVMITYHGVLMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLNNLSYWMYVC 140 Query: 109 GLVCLVTSTLVESG-----AGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAI 163 G+ V S L G +G GW +YPPLS+ +A G S+DLAIFA+H++ SS+LGAI Sbjct: 141 GVALGVASLLAPGGNDQMGSGVGWVLYPPLSTTEA--GYSMDLAIFAVHVSGASSILGAI 198 Query: 164 NFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEV 223 N I T LNMR GMT+ K+PLF WS+FITA+L+LLSLPVL+ ITMLL+DRNF T FF+ Sbjct: 199 NIITTFLNMRAPGMTLFKVPLFAWSVFITAWLILLSLPVLAGAITMLLMDRNFGTQFFDP 258 Query: 224 SGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLL 283 +GGGDP+LY+H+ WFFGHPEVYI+I+PGFGIISHV+ST++KKP+FG + MV AMA+IG+L Sbjct: 259 AGGGDPVLYQHILWFFGHPEVYIIILPGFGIISHVISTFAKKPIFGYLPMVLAMAAIGIL 318 Query: 284 GFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIA 343 GF+VW+HHMY G+ +AYF ATM IA+PTGIK+FSW+AT+ GGSI TPML+A Sbjct: 319 GFVVWAHHMYTAGMSLTQQAYFMLATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLWAFG 378 Query: 344 FLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGL 403 FLFLFT+GG+TGV L+ A LD +HDTYYVV HFHYV+S+GA+F +FAG YYW ++ G Sbjct: 379 FLFLFTVGGVTGVVLSQAPLDRVYHDTYYVVAHFHYVMSLGAVFGIFAGVYYWIGKMSGR 438 Query: 404 NYNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATL 463 Y E Q+ FW++FIG+N+IFFP HFLG GMPRR DYP FA WN ++SIG++I+ Sbjct: 439 QYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDYPVEFAYWNNISSIGAYISFA 498 Query: 464 SLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPA 523 S FI I++ L G V N +N+ D ++E+ L SPP Sbjct: 499 SFLFFIGIVFYTLFAGKRVNVPN---YWNEHAD----------------TLEWTLPSPPP 539 Query: 524 VHSFNT 529 H+F T Sbjct: 540 EHTFET 545 >3FYE-A nrPDB Length = 566 Score = 598 bits (1542), Expect = e-171, Method: Composition-based stats. Identities = 285/556 (51%), Positives = 381/556 (68%), Gaps = 51/556 (9%) Query: 4 RWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHG------------- 50 RW STN KDI VLY G+ A ++ +R+EL APG Q++ Sbjct: 19 RWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQ 78 Query: 51 ------------NSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRI 98 N L+NV++ GH +LM+FF+V+PAL GGFGNY +PL IGA D AFPR+ Sbjct: 79 SLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRM 138 Query: 99 NNIAFWVLPMGLVCLVTSTLVESG-----AGTGWTVYPPLSSIQAHSGPSVDLAIFALHL 153 NN+++W+ G V S G +G GW +YPPLS+ + SG S DLAIFA+HL Sbjct: 139 NNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLST--SESGYSTDLAIFAVHL 196 Query: 154 TSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLD 213 + SS+LGAIN I T LNMR GMTMHK+PLF WSIF+TA+L+LL+LPVL+ ITMLL D Sbjct: 197 SGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTD 256 Query: 214 RNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISM 273 RNF T+FF+ SGGGDP+LY+H+ WFFGHPEVYI+++P FGI+SHV++T++KKP+FG + M Sbjct: 257 RNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPM 316 Query: 274 VYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIR 333 VYAM +IG+LGF+VW+HHMY GL ++YF ATM+IA+PTGIKIFSW+AT+ GGSI Sbjct: 317 VYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIE 376 Query: 334 LATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGY 393 L TPML+A+ FLFLFT+GG+TG+ L+ AS+D +HDTYYVV HFHYV+S+GA+F +FAG Sbjct: 377 LKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGI 436 Query: 394 YYWSPQILGLNYNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYV 453 Y+W ++ G Y E ++ FW++F+GAN+ FFP HFLG GMPRR DYP+AFA WN+V Sbjct: 437 YFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFV 496 Query: 454 ASIGSFIATLSLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSS 513 +S+G+F++ S F+ +++ L G NN +N+ D + Sbjct: 497 SSLGAFLSFASFLFFLGVIFYTLTRGARVTANN---YWNEHAD----------------T 537 Query: 514 IEFLLTSPPAVHSFNT 529 +E+ LTSPP H+F Sbjct: 538 LEWTLTSPPPEHTFEQ 553 >6HWH-V nrPDB Length = 583 Score = 588 bits (1515), Expect = e-168, Method: Composition-based stats. Identities = 204/538 (37%), Positives = 312/538 (57%), Gaps = 30/538 (5%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 ++ + + +T+ K I ++Y + G M+L++R ELA PG Q+L +++ +N L Sbjct: 27 LLYKLVTTTDHKLIGMMYVVACFIFFFIGGLMALLLRTELAVPGLQFL--SNEQYNQLFT 84 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 H +M+ F P ++ GF N ++PL IGA D AFPR+N ++FW+ G + L Sbjct: 85 MHGTVMLLFYATP-IVFGFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGGFLAP 143 Query: 121 SG-AGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTM 179 G A GWT Y PLS+ G DL IF L + + ++LGA+N I T + MR GM M Sbjct: 144 GGPADFGWTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAPGMIM 203 Query: 180 HKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFF 239 ++P+F W+I +T+ ++L++ P+L++ + L DRN F+ + GG +L+EHLFWFF Sbjct: 204 FRMPIFTWNILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANGGT-MLWEHLFWFF 262 Query: 240 GHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDA 299 GHPEVYI+ +P FGI++ + +S+KPVFG ++VYA SIG L VW+HH+Y G A Sbjct: 263 GHPEVYIIALPFFGIVTEIFPVFSRKPVFGYTTLVYATISIGALSIAVWAHHLYATG--A 320 Query: 300 DTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALA 359 +F+ T +IA+PTGIK +W+ T+ G + TPML+++ FL F +GGLTGV LA Sbjct: 321 VLLPFFSFMTFMIAVPTGIKFVNWIGTMWKGQLTFETPMLFSVGFLVTFLLGGLTGVILA 380 Query: 360 NASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFI 419 + LD D+Y+VV HFHYVL +F+ +AG Y+W P++ G +++L ++ FWL I Sbjct: 381 SPPLDFHVTDSYFVVAHFHYVLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFWLTLI 440 Query: 420 GANVIFFPMHFLGINGMPRRIPDY--PDAFAGWNYVASIGSFIATLSLFLFIYILYDQLV 477 G + F H+LG GMPRR DY D F N V++IGSFI +S+ F++ ++ Sbjct: 441 GFHTTFLVHHWLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPFVWNVFKSWR 500 Query: 478 NGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNT-PAVQS 534 G V++ N S+E+ + PP H+F P ++S Sbjct: 501 YGEPVTVDDPWGYGN--------------------SLEWATSCPPPRHNFTELPRIRS 538 >6ADQ-F nrPDB Length = 575 Score = 583 bits (1504), Expect = e-167, Method: Composition-based stats. Identities = 198/538 (36%), Positives = 313/538 (58%), Gaps = 30/538 (5%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 ++ + + +T+ K I ++Y ++ + G M+L +R ELA PG Q+L +++ FN L Sbjct: 27 LIYKLITTTDHKLIGIMYCVVCFAFFLVGGLMALFMRTELAMPGLQFL--SNEQFNQLFT 84 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 H +M+ F P ++ GF N +LPL IGA D AFPR+N ++FW+ G + + + Sbjct: 85 MHGTVMLLFYATP-IVFGFANLVLPLQIGAPDVAFPRLNALSFWLFLFGALIAIAGFITP 143 Query: 121 SGA-GTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTM 179 GA GWT Y PL+ G DL I L + + ++LG +N I T + MR GMTM Sbjct: 144 GGAADFGWTAYSPLTDAIHSPGAGGDLWIMGLAVGGLGTILGGVNMITTVVCMRAPGMTM 203 Query: 180 HKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFF 239 ++P+F W+I +T+ L+L++ P+L+A + L DR+ ++ + GG +L++HLFWFF Sbjct: 204 FRMPIFTWNILVTSILVLIAFPILTAALFGLAADRHLGAHIYDPANGGV-LLWQHLFWFF 262 Query: 240 GHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDA 299 GHPEVYI+ +P FGI+S + +S+KP+FG +++YA +I L VW+HHMY G A Sbjct: 263 GHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLAIAALSVAVWAHHMYATG--A 320 Query: 300 DTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALA 359 +F+ T +IA+PTGIK F+W+ T+ G + TPML+++ FL F +GGL+GV LA Sbjct: 321 VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFLITFLLGGLSGVLLA 380 Query: 360 NASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFI 419 + LD D+Y+V+ HFHYVL +F+ +AG Y+W P++ G +E+L ++ FWL FI Sbjct: 381 SPPLDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFI 440 Query: 420 GANVIFFPMHFLGINGMPRRIPDY--PDAFAGWNYVASIGSFIATLSLFLFIYILYDQLV 477 G + F H+LG GMPRR DY D F N ++++G+FI +S+ F++ ++ Sbjct: 441 GFHTTFLVQHWLGDEGMPRRYADYLPTDGFTTLNVISTVGAFILGVSMLPFVWNVFKSWR 500 Query: 478 NGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNT-PAVQS 534 G V++ N S+E+ + PP H+F P ++S Sbjct: 501 YGEPVTVDDPWGYGN--------------------SLEWATSCPPPRHNFTELPRIRS 538 >3ASN-A nrPDB Length = 514 Score = 578 bits (1490), Expect = e-165, Method: Composition-based stats. Identities = 300/531 (56%), Positives = 400/531 (75%), Gaps = 25/531 (4%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 + RWL+STN KDI LY + ++GM GTA+SL+IR EL PG+ L G+ Q++NV+V Sbjct: 2 FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGT--LLGDDQIYNVVVT 59 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 HA +MIFF+VMP +IGGFGN+L+PLMIGA D AFPR+NN++FW+LP + L+ S++VE Sbjct: 60 AHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVE 119 Query: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180 +GAGTGWTVYPPL+ AH+G SVDL IF+LHL +SS+LGAINFI T +NM+ M+ + Sbjct: 120 AGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQY 179 Query: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFG 240 + PLFVWS+ ITA LLLLSLPVL+AGITMLL DRN NT+FF+ +GGGDPILY+HLFWFFG Sbjct: 180 QTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFG 239 Query: 241 HPEVYILIIPGFGIISHVVSTYS-KKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDA 299 HPEVYILI+PGFG+ISH+V+ YS KK FG + MV+AM SIG LGF+VW+HHM+ VG+D Sbjct: 240 HPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDV 299 Query: 300 DTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALA 359 DTRAYFTSATMIIAIPTG+K+FSWLAT+HGG+I+ + M++A+ F+FLFT+GGLTG+ LA Sbjct: 300 DTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLA 359 Query: 360 NASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFI 419 N+SLD+ HDTYYVV HFHYVLSMGA+F++ G+ +W P G N+ A+I F ++F+ Sbjct: 360 NSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFV 419 Query: 420 GANVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNG 479 G N+ FFP HFLG++GMPRR DYPDA+ WN ++S+GSFI+ ++ L ++I+++ + Sbjct: 420 GVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASK 479 Query: 480 LNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTP 530 + + ++++E+L PP H+F P Sbjct: 480 REVLTVD----------------------LTTTNLEWLNGCPPPYHTFEEP 508 >5Z62-A nrPDB Length = 513 Score = 577 bits (1488), Expect = e-165, Method: Composition-based stats. Identities = 301/529 (56%), Positives = 398/529 (75%), Gaps = 25/529 (4%) Query: 3 QRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGH 62 RWL+STN KDI LY + ++G+ GTA+SL+IR EL PG+ L GN ++NV+V H Sbjct: 4 DRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAH 61 Query: 63 AVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESG 122 A +MIFF+VMP +IGGFGN+L+PLMIGA D AFPR+NN++FW+LP L+ L+ S +VE+G Sbjct: 62 AFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAG 121 Query: 123 AGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKL 182 AGTGWTVYPPL+ +H G SVDL IF+LHL +SS+LGAINFI T +NM+ MT ++ Sbjct: 122 AGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQT 181 Query: 183 PLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHP 242 PLFVWS+ ITA LLLLSLPVL+AGITMLL DRN NT+FF+ +GGGDPILY+HLFWFFGHP Sbjct: 182 PLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHP 241 Query: 243 EVYILIIPGFGIISHVVSTYS-KKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADT 301 EVYILI+PGFG+ISH+V+ YS KK FG + MV+AM SIG LGF+VW+HHM+ VG+D DT Sbjct: 242 EVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDT 301 Query: 302 RAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANA 361 RAYFTSATMIIAIPTG+K+FSWLAT+HG +++ + +L+A+ F+FLFT+GGLTG+ LAN+ Sbjct: 302 RAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLANS 361 Query: 362 SLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIGA 421 SLD+ HDTYYVV HFHYVLSMGA+F++ G+ +W P G ++ A+I F ++FIG Sbjct: 362 SLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGV 421 Query: 422 NVIFFPMHFLGINGMPRRIPDYPDAFAGWNYVASIGSFIATLSLFLFIYILYDQLVNGLN 481 N+ FFP HFLG++GMPRR DYPDA+ WN ++S+GSFI+ ++ L I+++++ Sbjct: 422 NLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAF----- 476 Query: 482 NKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTP 530 + + V+ + P S ++E+L PP H+F P Sbjct: 477 --ASKRKVLMVEEP---------------SMNLEWLYGCPPPYHTFEEP 508 >1FFT-A nrPDB Length = 663 Score = 541 bits (1394), Expect = e-154, Method: Composition-based stats. Identities = 193/530 (36%), Positives = 296/530 (55%), Gaps = 24/530 (4%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLE--LAAPGSQYLHGNSQLFNVL 58 + + WL S + K + ++Y ++AI + G A ++++R + LA+ G ++ + Sbjct: 44 LWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHH-YDQI 102 Query: 59 VVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTL 118 H V+MIFF+ MP +I G N ++PL IGA D AFP +NN++FW +G++ + S Sbjct: 103 FTAHGVIMIFFVAMPFVI-GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLG 161 Query: 119 VESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMT 178 V A TGW YPPLS I+ G VD I++L L+ I + L INF VT L MR GMT Sbjct: 162 VGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMT 221 Query: 179 MHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWF 238 M K+P+F W+ L++ S P+L+ + +L LDR T FF GG+ ++Y +L W Sbjct: 222 MFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWA 281 Query: 239 FGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLD 298 +GHPEVYILI+P FG+ S + +T+S+K +FG S+V+A I +L F+VW HH + +G Sbjct: 282 WGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAG 341 Query: 299 ADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVAL 358 A+ A+F TMIIAIPTG+KIF+WL T++ G I + ML+ I F+ F++GG+TGV L Sbjct: 342 ANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLL 401 Query: 359 ANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIF 418 A D H++ +++ HFH V+ G +F FAG YW P+ G NE + FW Sbjct: 402 AVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWI 461 Query: 419 IGANVIFFPMHFLGINGMPRRIPDYPD-AFAGWNYVASIGSFIATLSLFLFIYILYDQLV 477 IG V F P++ LG GM RR+ D F +A+ G+ + L + + +Y + Sbjct: 462 IGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIR 521 Query: 478 NGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSF 527 + N+ + ++E+ +SPP ++F Sbjct: 522 DRDQNR-------------------DLTGDPWGGRTLEWATSSPPPFYNF 552 >2YEV-A nrPDB Length = 791 Score = 504 bits (1297), Expect = e-143, Method: Composition-based stats. Identities = 204/532 (38%), Positives = 313/532 (58%), Gaps = 31/532 (5%) Query: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60 ++ L + + K I ++Y A F+ SL+IR +LA P +Q+L G + +N ++ Sbjct: 14 VLWDLLTTVDHKKIGLMYTATAFFAFALAGVFSLLIRTQLAVPNNQFLTG--EQYNQILT 71 Query: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120 H M+FF ++ A + GFGN+++PLM+GA D A PR+N ++W +V + S Sbjct: 72 LHGATMLFFFIIQAGLTGFGNFVVPLMLGARDVALPRVNAFSYWAFLGAIVLALMSYFFP 131 Query: 121 SGA-GTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTM 179 GA GWT Y P S A S VD + A+ L SSLLG NF+ T N+R GM++ Sbjct: 132 GGAPSVGWTFYYPFS---AQSESGVDFYLAAILLLGFSSLLGNANFVATIYNLRAQGMSL 188 Query: 180 HKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFF 239 K+P++VWS+F + L L SL L+A ++LL+R S+F + GGDP+L++ FWF+ Sbjct: 189 WKMPIYVWSVFAASVLNLFSLAGLTAATLLVLLERKIGLSWFNPAVGGDPVLFQQFFWFY 248 Query: 240 GHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDA 299 HP VY++++P GI++ V ST+++KP+FG MV+A I +LG +VW+HHM+ VG Sbjct: 249 SHPTVYVMLLPYLGILAEVASTFARKPLFGYRQMVWAQMGIVVLGTMVWAHHMFTVGEST 308 Query: 300 DTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALA 359 + F T +IA+PTG+K+F+ + T+ GG +++ TP+ + + F+F F +GG+TGV L+ Sbjct: 309 LFQIAFAFFTALIAVPTGVKLFNIIGTLWGGKLQMKTPLYWVLGFIFNFLLGGITGVMLS 368 Query: 360 NASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFI 419 LD FHD+Y+VV HFH VL G+ F FAG YYW P++ G Y+E+L ++ FWL + Sbjct: 369 MTPLDYQFHDSYFVVAHFHNVLMAGSGFGAFAGLYYWWPKMTGRMYDERLGRLHFWLFLV 428 Query: 420 GANVIFFPMHFLGINGMPRRIPDYPDAFAGW---NYVASIGSFIATLSLFLFIYILYDQL 476 G + F P + LG GMPRR Y AGW N +++IG++I L ++IY ++ L Sbjct: 429 GYLLTFLPQYALGYLGMPRRYYTYNADIAGWPELNLLSTIGAYILGLGGLVWIYTMWKSL 488 Query: 477 VNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFN 528 +G KAPD N ++E+L SPP H+F+ Sbjct: 489 RSG------------PKAPD----------NPWGGYTLEWLTASPPKAHNFD 518 >3EH4-A nrPDB Length = 618 Score = 211 bits (536), Expect = 8e-55, Method: Composition-based stats. Identities = 109/519 (21%), Positives = 198/519 (38%), Gaps = 68/519 (13%) Query: 2 VQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLEL----AAPGSQYLHGNSQLFNV 57 + R + K + + +L + + G+ L A P + L Q + Sbjct: 64 ISRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQ 123 Query: 58 LVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTST 117 + H VL + + + +++W+ +GLV Sbjct: 124 GLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMG---LMWLSWWMAFIGLVVAALPL 180 Query: 118 LVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNM--RTN 175 L A +T YPPL +A +L + +L I L++ R Sbjct: 181 LANE-ATVLYTFYPPLKGH------------WAFYLGASVFVLSTWVSIYIVLDLWRRWK 227 Query: 176 GMTMHKLPLFVWSIFITAFLL--LLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYE 233 K+ V + + +L+ L SL ++ + LL F + G DP++ Sbjct: 228 AANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLL------PWSFGLVEGVDPLVAR 281 Query: 234 HLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMY 293 LFW+ GHP VY ++P + II ++ + + + A LL V HH + Sbjct: 282 TLFWWTGHPIVYFWLLPAYAIIYTILPKQAGGRLVSDPMARLAFLLFLLLSTPVGFHHQF 341 Query: 294 I-VGLDADTRAYFTSATMIIAIPT-------------------GIKIFSWLATIHGGSIR 333 G+D + + T+ +A+P+ G +F W+ + + Sbjct: 342 ADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPA 401 Query: 334 LATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGY 393 P+L + F+ GG G+ A+ +LD H+T +V GHFH ++ + Sbjct: 402 FVAPVLGLLGFI----PGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSL 457 Query: 394 YYWSPQILGL---NYNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRR--IPDYPDAFA 448 Y+ P + G + +L WL F+G ++ +H+ G+ +PRR I PDA+ Sbjct: 458 YWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYP 517 Query: 449 G------WNYVASIGSFIATLSLFLFIYILYDQLVNGLN 481 +N +A I + ++L LFIY L+ L++ Sbjct: 518 HAAVPMVFNVLAGI---VLLVALLLFIYGLFSVLLSRER 553 >3MK7-A nrPDB Length = 474 Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 45/266 (16%), Positives = 95/266 (35%), Gaps = 17/266 (6%) Query: 237 WFFGHPEVYILIIPGF-GIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIV 295 W++GH V + GF GI+ + V +++PV+ + ++ + HH++ Sbjct: 203 WWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYT 262 Query: 296 GLDADTRAYFTSATMIIAIPTGIKIFSWLATIH--GGSIRLATPMLYAIAFLFLFTMGGL 353 L ++ ++I+ P+ + + + T+ +R + + + L + M Sbjct: 263 ALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTF 322 Query: 354 TGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQI- 412 G +A +++ H T + +GH H Y+ P++ G + I Sbjct: 323 EGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLIN 382 Query: 413 -QFWLIFIGANVIFFPMHFLGIN------------GMPRRIPDYPDAFAGWNYVASIGSF 459 FWL IG + M GI + + +A V IG Sbjct: 383 THFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGA 442 Query: 460 IATLSLFLFIYILYDQLVNGLNNKVN 485 I + + Y + + + + Sbjct: 443 IFFAGMLVMAYNTWRTVQAAKPAEYD 468 >4XYD-A nrPDB Length = 456 Score = 45.4 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 37/194 (19%), Positives = 69/194 (35%), Gaps = 12/194 (6%) Query: 290 HHMYIVGLDADTRAYFTSATMIIAIPT-GIKIFSWLATIHGGSIRL--ATPMLYAIAFLF 346 HH + +G + + + + +P G+ F+++ + G +L+++ Sbjct: 245 HHYFWIGTPGYWQWIGSIFSALEVVPFFGMMAFAFV-MVWKGRKDHPNKAALLWSLGCAT 303 Query: 347 LFTMG-GLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLN- 404 L G G+ G ++ H T H H + A + Y P + + Sbjct: 304 LAFFGAGVWGFLHTLHGINYYTHGTQITAAHGHLAFFGAYVSLNLAIFSYAFPILRKRDP 363 Query: 405 YNEKLAQIQFWLIFIGANVIFFPMHFLGINGMPRR------IPDYPDAFAGWNYVASIGS 458 YN+ L FWL+ G + F + F G + D DA + ++ Sbjct: 364 YNQVLNMASFWLMAGGMTFMTFVLTFAGTVQTHAQRVQGDYFMDVQDAITIFYWMRFGSG 423 Query: 459 FIATLSLFLFIYIL 472 L LFIY + Sbjct: 424 IAVVLGALLFIYAV 437 >5GUW-B nrPDB Length = 465 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 72/433 (16%), Positives = 153/433 (35%), Gaps = 53/433 (12%) Query: 18 YFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIG 77 YF+ A+ + LI+ L+ + + FNV + H L+I +L+ Sbjct: 19 YFVFALILFVGQILFGLIMGLQYVVGDFLF---PAIPFNVARMVHTNLLIVWLL--FGFM 73 Query: 78 GFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQ 137 G YL+P + P++ I FWV V + L+ AG L+ + Sbjct: 74 GAAYYLVPEESDC-ELYSPKLAWILFWVFAAAGVLTILGYLLVPYAGLA-----RLTGNE 127 Query: 138 AHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLL 197 + + ++ ++ A+ F+ GMT+ + S+ + L+ Sbjct: 128 LWPTMGREF-LEQPTISKAGIVIVALGFLFNV------GMTVLRGRKTAISMVLMTGLIG 180 Query: 198 LSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISH 257 L+L L SF+ + + +W++ V++ + + +I Sbjct: 181 LALLFL--------------FSFYNPEN----LTRDKFYWWW---VVHLWVEGVWELIMG 219 Query: 258 VVSTYSKKPVFGEISMV-----YAMASIGLLGFLVWS-HHMYIVGLDADTRAYFTSATMI 311 + + + G V Y + ++ L+ ++ + HH + +G+ + + + Sbjct: 220 AILAFVLVKITGVDREVIEKWLYVIIAMALISGIIGTGHHYFWIGVPGYWLWLGSVFSAL 279 Query: 312 IAIPTGIKIFSWLATIHGGSIRL--ATPMLYAIAFLFLFTMG-GLTGVALANASLDVAFH 368 +P + TI+ L+A+ + +G G+ G A ++ H Sbjct: 280 EPLPFFAMVLFAFNTINRRRRDYPNRAVALWAMGTTVMAFLGAGVWGFMHTLAPVNYYTH 339 Query: 369 DTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGL-----NYNEKLAQIQFWLIFIGANV 423 T H H + Y P++ G+ N ++ L FWL+ + Sbjct: 340 GTQLTAAHGHMAFYGAYAMIVMTIISYAMPRLRGIGEAMDNRSQVLEMWGFWLMTVAMVF 399 Query: 424 IFFPMHFLGINGM 436 I + G+ + Sbjct: 400 ITLFLSAAGVLQV 412 >3AYF-A nrPDB Length = 800 Score = 31.1 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 33/197 (16%), Positives = 65/197 (32%), Gaps = 11/197 (5%) Query: 232 YEHLFWFFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHH 291 + W G EV+ +++ GF ++ + +KK ++ + + G + HH Sbjct: 505 WIIHLWVEGIFEVFAVVVIGFLLVQ--LRLVTKKSTV--RALYFQFTILLGSGVIGIGHH 560 Query: 292 MYIVGLDADTRAYFTSATMIIAIPTGIKIFSWLATIH-----GGSIRLATPMLYAIAFLF 346 Y G A + + IP + I G + + I+ Sbjct: 561 YYYNGSPEVWIALGAVFSALEVIPLTLLILEAYEQYKMMRDGGANFPYKATFWFLISTAI 620 Query: 347 LFTMG-GLTGVALANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNY 405 +G G+ G + ++ H + H H + A Y I+ Sbjct: 621 WNLVGAGVFGFLINLPAVSYFEHGQFLTPAHGHAAMMGVYGMFAIAVLLYSLRNIVKPEA 680 Query: 406 -NEKLAQIQFWLIFIGA 421 N+K + W++ IG Sbjct: 681 WNDKWLKFSCWMLNIGL 697 >2XZ4-A nrPDB Length = 180 Score = 29.6 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 17/55 (30%), Gaps = 2/55 (3%) Query: 124 GTGWT--VYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNG 176 GW Y L I H+ ++ +I FI T +NM Sbjct: 65 SFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPA 119 >5W8S-A nrPDB Length = 382 Score = 29.2 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%) Query: 332 IRLATPMLYAIAFLFLFTMGGLTGVALANASLDVAFHDTYYVVGHF 377 I +P ++A +F +G T + LA + AF+D Y V F Sbjct: 118 IHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRF 163 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.322 0.138 0.424 Lambda K H 0.267 0.0422 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,852,742 Number of Sequences: 36641 Number of extensions: 989868 Number of successful extensions: 3154 Number of sequences better than 10.0: 57 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 3000 Number of HSP's gapped (non-prelim): 94 length of query: 534 length of database: 10,336,785 effective HSP length: 102 effective length of query: 432 effective length of database: 6,599,403 effective search space: 2850942096 effective search space used: 2850942096 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.4 bits) S2: 62 (28.4 bits)