BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00388 (678 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6J79-A nrPDB 1294 0.0 3ES9-A nrPDB 1291 0.0 3QFR-A nrPDB 1222 0.0 3FJO-A nrPDB 985 0.0 5GXU-A nrPDB 441 e-124 1B1C-A nrPDB 365 e-101 2BN4-A nrPDB 317 1e-86 1TLL-A nrPDB 252 3e-67 6EFV-A nrPDB 245 5e-65 1BVY-F nrPDB 80 2e-15 4H2D-A nrPDB 79 7e-15 3HR4-A nrPDB 68 2e-11 4OXX-A nrPDB 68 2e-11 2B5O-A nrPDB 65 1e-10 1YKG-A nrPDB 58 1e-08 5VEG-A nrPDB 58 1e-08 2HNA-A nrPDB 52 7e-07 6FSI-A nrPDB 48 1e-05 6GAQ-A nrPDB 48 1e-05 5LJI-A nrPDB 48 2e-05 2M6S-A nrPDB 47 3e-05 3F6S-A nrPDB 47 3e-05 5V57-A nrPDB 46 5e-05 5YOB-A nrPDB 45 8e-05 5ZKP-A nrPDB 45 1e-04 5XRA-A nrPDB 45 1e-04 4HEQ-A nrPDB 42 7e-04 5B3K-A nrPDB 39 0.010 5OGX-A nrPDB 38 0.018 1CZN-A nrPDB 37 0.020 3KAQ-A nrPDB 36 0.061 1WXQ-A nrPDB 33 0.56 2BMV-A nrPDB 32 0.61 1KRH-A nrPDB 32 0.66 1AG9-A nrPDB 32 0.98 4V7I-AA nrPDB 32 1.0 2YXR-A nrPDB 32 1.0 2V5U-A nrPDB 31 1.4 2WC1-A nrPDB 31 1.7 6BDE-A nrPDB 30 3.0 1PQN-A nrPDB 29 8.5 >6J79-A nrPDB Length = 871 Score = 1294 bits (3349), Expect = 0.0, Method: Compositional matrix adjust. Identities = 617/622 (99%), Positives = 618/622 (99%), Gaps = 4/622 (0%) Query: 57 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 116 +QTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE Sbjct: 254 MQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 313 Query: 117 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 176 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK Sbjct: 314 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 373 Query: 177 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEAT 236 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA Sbjct: 374 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA- 432 Query: 237 GEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 296 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT Sbjct: 433 ---SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 489 Query: 297 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 356 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN Sbjct: 490 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 549 Query: 357 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 416 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY Sbjct: 550 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 609 Query: 417 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 476 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV Sbjct: 610 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 669 Query: 477 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 536 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG Sbjct: 670 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 729 Query: 537 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 596 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS Sbjct: 730 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 789 Query: 597 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 656 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH Sbjct: 790 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 849 Query: 657 TQAVDYVKKLMTKGRYSLDVWS 678 TQAVDYVKKLMTKGRYSLDVWS Sbjct: 850 TQAVDYVKKLMTKGRYSLDVWS 871 >3ES9-A nrPDB Length = 618 Score = 1291 bits (3342), Expect = 0.0, Method: Compositional matrix adjust. Identities = 618/622 (99%), Positives = 618/622 (99%), Gaps = 4/622 (0%) Query: 57 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 116 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE Sbjct: 1 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 60 Query: 117 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 176 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK Sbjct: 61 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 120 Query: 177 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEAT 236 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA Sbjct: 121 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA- 179 Query: 237 GEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 296 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT Sbjct: 180 ---SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 236 Query: 297 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 356 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN Sbjct: 237 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 296 Query: 357 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 416 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY Sbjct: 297 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 356 Query: 417 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 476 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV Sbjct: 357 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 416 Query: 477 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 536 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG Sbjct: 417 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 476 Query: 537 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 596 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS Sbjct: 477 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 536 Query: 597 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 656 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH Sbjct: 537 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 596 Query: 657 TQAVDYVKKLMTKGRYSLDVWS 678 TQAVDYVKKLMTKGRYSLDVWS Sbjct: 597 TQAVDYVKKLMTKGRYSLDVWS 618 >3QFR-A nrPDB Length = 618 Score = 1222 bits (3162), Expect = 0.0, Method: Compositional matrix adjust. Identities = 577/615 (93%), Positives = 599/615 (97%), Gaps = 1/615 (0%) Query: 64 VKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 123 V+ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS Sbjct: 5 VRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 64 Query: 124 SLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNA 183 SLPEID +LVVFCMATYGEGDPTDNAQDFYDWLQETDVDL+GVKFAVFGLGNKTYEHFNA Sbjct: 65 SLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNA 124 Query: 184 MGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIR 243 MGKYVD+RLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCE FGVEATGEESSIR Sbjct: 125 MGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESSIR 184 Query: 244 QYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHL 303 QYELVVH D+D AKVY GEMGRLKSYENQKPPFDAKNPFLAAVT NRKLNQGTERHLMHL Sbjct: 185 QYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHL 244 Query: 304 ELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPC 363 ELDISDSKIRYESGDHVAVYPANDSALVNQ+G+ILGADLDV+MSLNNLDEESNKKHPFPC Sbjct: 245 ELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPC 304 Query: 364 PTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEA 423 PT+YRTALTYYLDITNPPRTNVLYELAQYASEPSEQE L KMASSSGEGKELYLSWVVEA Sbjct: 305 PTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEA 364 Query: 424 RRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSG 483 RRHILAILQD PSLRPPIDHLCELLPRLQA YYSIASSSKVHPNSVHICAV VEYE K+G Sbjct: 365 RRHILAILQDCPSLRPPIDHLCELLPRLQAHYYSIASSSKVHPNSVHICAVVVEYETKAG 424 Query: 484 RVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGF 543 R+NKGVAT+WLRAKEPAGENGGRALVPMFVRKSQFRLPFK+TTPVIMVGPGTG+APF+GF Sbjct: 425 RINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGF 484 Query: 544 IQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKV 603 IQERAWLR+QGKEVGETLLYYGCRRSDEDYLYREELA+FH+DGALTQLNVAFSREQ+HKV Sbjct: 485 IQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKV 544 Query: 604 YVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYV 663 YVQHLLK+DREHLWKLI EGGAHIYVCGDARNMA+DVQNTFYDIVAE G MEH QAVDY+ Sbjct: 545 YVQHLLKQDREHLWKLI-EGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYI 603 Query: 664 KKLMTKGRYSLDVWS 678 KKLMTKGRYSLDVWS Sbjct: 604 KKLMTKGRYSLDVWS 618 >3FJO-A nrPDB Length = 637 Score = 985 bits (2546), Expect = 0.0, Method: Compositional matrix adjust. Identities = 473/609 (77%), Positives = 526/609 (86%), Gaps = 8/609 (1%) Query: 73 MKKTGRNIIVFYGSQTGTAEEFANRLSKD-AHRYGMRGMSADPEEYDLADLSSLPEIDKS 131 + + +N +V Y SQTGTAE++A + SK+ ++ + M AD E YD L+ +P I Sbjct: 34 VTENNKNYLVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENYDFESLNDVPVI--- 90 Query: 132 LVVFCMATYGEGDPTDNAQDFYDWLQETDVD-LTGVKFAVFGLGNKTYEHFNAMGKYVDQ 190 V ++TYGEGD D A +F D++ + L+ +++ +FGLGN TYE FN K ++ Sbjct: 91 -VSIFISTYGEGDFPDGAVNFEDFICNAEAGALSNLRYNMFGLGNSTYEFFNGAAKKAEK 149 Query: 191 RLEQLGAQRIFELGLGDDD-GNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVV 249 L GA R+ +LG DD G +ED++ W++ + + GVEATGEESSIRQYELVV Sbjct: 150 HLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELGVEATGEESSIRQYELVV 209 Query: 250 HEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISD 309 H D+D AKVY GEMGRLKSYENQKPPFDAKNPFLAAVT NRKLNQGTERHLMHLELDISD Sbjct: 210 HTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISD 269 Query: 310 SKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRT 369 SKIRYESGDHVAVYPANDSALVNQ+G+ILGADLDV+MSLNNLDEESNKKHPFPCPT+YRT Sbjct: 270 SKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPTSYRT 329 Query: 370 ALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILA 429 ALTYYLDITNPPRTNVLYELAQYASEPSEQE L KMASSSGEGKELYLSWVVEARRHILA Sbjct: 330 ALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILA 389 Query: 430 ILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGV 489 ILQD PSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAV VEYE K+GR+NKGV Sbjct: 390 ILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRINKGV 449 Query: 490 ATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAW 549 AT+WLRAKEPAGENGGRALVPMFVRKSQFRLPFK+TTPVIMVGPGTG+APF+GFIQERAW Sbjct: 450 ATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAW 509 Query: 550 LREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLL 609 LR+QGKEVGETLLYYGCRRSDEDYLYREELA+FH+DGALTQLNVAFSREQ+HKVYVQHLL Sbjct: 510 LRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKVYVQHLL 569 Query: 610 KRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTK 669 K+DREHLWKLI EGGAHIYVCGDARNMA+DVQNTFYDIVAE G MEH QAVDY+KKLMTK Sbjct: 570 KQDREHLWKLI-EGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTK 628 Query: 670 GRYSLDVWS 678 GRYSLDVWS Sbjct: 629 GRYSLDVWS 637 >5GXU-A nrPDB Length = 640 Score = 441 bits (1133), Expect = e-124, Method: Compositional matrix adjust. Identities = 249/624 (39%), Positives = 366/624 (58%), Gaps = 25/624 (4%) Query: 71 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAH-RY-GMRGMSADPEEYDLADLSSLPEI 128 E++ + + +F+G+QTGTAE FA L ++A RY R D ++Y D ++ Sbjct: 25 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 84 Query: 129 DKSLVVFC-MATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGLGNKTYEHFNAM 184 K V F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN + Sbjct: 85 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 144 Query: 185 GKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVE-----ATGEE 239 K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E AT Sbjct: 145 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYT 204 Query: 240 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQG-TER 298 +++ +Y + +H+ D AK M Y FDA++P+ A V R+L+ ++R Sbjct: 205 AAVLEYRVSIHDSED-AKFNDINMANGNGYT----VFDAQHPYKANVAVKRELHTPESDR 259 Query: 299 HLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKK 358 +HLE DI+ S + YE+GDHV V N S V++ +L D SL+ E+ Sbjct: 260 SCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPI 319 Query: 359 HPFPCP----TTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKE 414 P RTALT Y + + P+ + L LA +AS+P+E E L +AS +G K+ Sbjct: 320 SSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG--KD 377 Query: 415 LYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHICA 473 Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ +H+ Sbjct: 378 EYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTC 437 Query: 474 VAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGP 533 V + +GR++KGV ++W++ P ++ + P+FVR+S F+LP S P+IM+GP Sbjct: 438 ALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGP 497 Query: 534 GTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNV 593 GTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF + GAL +L+V Sbjct: 498 GTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSV 557 Query: 594 AFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGP 653 AFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV + + I E G Sbjct: 558 AFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSLHTIAQEQGS 616 Query: 654 MEHTQAVDYVKKLMTKGRYSLDVW 677 M+ T+A +VK L T GRY DVW Sbjct: 617 MDSTKAEGFVKNLQTSGRYLRDVW 640 >1B1C-A nrPDB Length = 181 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 172/178 (96%), Positives = 176/178 (98%) Query: 64 VKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 123 V+ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS Sbjct: 4 VRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 63 Query: 124 SLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNA 183 SLPEID +LVVFCMATYGEGDPTDNAQDFYDWLQETDVDL+GVKFAVFGLGNKTYEHFNA Sbjct: 64 SLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNA 123 Query: 184 MGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESS 241 MGKYVD+RLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCE FGVEATGEESS Sbjct: 124 MGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESS 181 >2BN4-A nrPDB Length = 682 Score = 317 bits (812), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 223/655 (34%), Positives = 336/655 (51%), Gaps = 67/655 (10%) Query: 73 MKKTGRNIIVFYGSQTGTAEEFANRLSKD-AHRYGMRGMSADPEEYDLADLSSLPEIDKS 131 + + +N +V Y SQTGTAE++A + SK+ ++ + M AD E YD L+ +P I Sbjct: 45 VTENNKNYLVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENYDFESLNDVPVI--- 101 Query: 132 LVVFCMATYGEGDPTDNAQDFYDWLQETDVD-LTGVKFAVFGLGNKTYEHFNAMGKYVDQ 190 V ++TYGEGD D A +F D++ + L+ +++ +FGLGN TYE FN K ++ Sbjct: 102 -VSIFISTYGEGDFPDGAVNFEDFICNAEAGALSNLRYNMFGLGNSTYEFFNGAAKKAEK 160 Query: 191 RLEQLGAQRIFELGLGDDD-GNLEEDFITWREQFWPAVCEFFGV-EATGEESSIRQYELV 248 L GA R+ +LG DD G +ED++ W++ + + + E + +S QY V Sbjct: 161 HLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDEQEAKFTSQFQYT-V 219 Query: 249 VHEDMDVAKVYTGEMGRLKSYE-------NQKPPFDAKNPFLAAVTANRKLNQGTERHLM 301 ++E D + L S++ Q PFD P++A + +R+L +R+ + Sbjct: 220 LNEITDSMSLGEPSAHYLPSHQLNRNADGIQLGPFDLSQPYIAPIVKSRELFSSNDRNCI 279 Query: 302 HLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPF 361 H E D+S S I+Y +GDH+AV+P+N V Q I D + I L LD K PF Sbjct: 280 HSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLSIFNLDPETIFDLKPLD--PTVKVPF 337 Query: 362 PCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVV 421 P PTT A+ +YL+IT P + L Q+A +E L ++ + + V Sbjct: 338 PTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLLSKDKDQ-------FAV 390 Query: 422 EARRHILAILQDYPSLRP-------PIDHLCELLPRLQARYYSIASSSKVHPNSVHICAV 474 E I L P+ L E +P++ RYYSI+SSS +VH+ ++ Sbjct: 391 EITSKYFNIADALKYLSDGAKWDTVPMQFLVESVPQMTPRYYSISSSSLSEKQTVHVTSI 450 Query: 475 AVEY---EAKSGRVNKGVATSWLRAKEPAGE---------------NGGRAL-----VPM 511 + E GV T+ LR + A NG R L +P+ Sbjct: 451 VENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGPRKLFANYKLPV 510 Query: 512 FVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQER-AWLREQGK-----EVGETLLYYG 565 VR+S FRLP +TPVIM+GPGTG+APF GFI+ER A+L Q K +G+ +L+YG Sbjct: 511 HVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGGNNVSLGKHILFYG 570 Query: 566 CRRSDEDYLYREELARFHK--DGALTQLNVAFSR-EQAHKVYVQHLLKRDREHLWKLIHE 622 R +D D+LY++E + K DG+ ++ VA SR KVYVQ LK + ++++I+ Sbjct: 571 SRNTD-DFLYQDEWPEYAKKLDGSF-EMVVAHSRLPNTKKVYVQDKLKDYEDQVFEMINN 628 Query: 623 GGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVW 677 GA IYVCGDA+ MAK V I++ + +A + +K L T GRY DVW Sbjct: 629 -GAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKTSGRYQEDVW 682 >1TLL-A nrPDB Length = 688 Score = 252 bits (644), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 196/673 (29%), Positives = 313/673 (46%), Gaps = 111/673 (16%) Query: 82 VFYGSQTGTAEEFANRLSKD-AHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATY 140 + Y ++TG ++ +A L + H + + MS EEYD+ L ++LV+ +T+ Sbjct: 16 ILYATETGKSQAYAKTLCEIFKHAFDAKAMSM--EEYDIVHLEH-----EALVLVVTSTF 68 Query: 141 GEGDPTDNAQDFYDWLQE------------------------------------------ 158 G GDP +N + F L E Sbjct: 69 GNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSRKSSGDGPDLRDNFE 128 Query: 159 TDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFIT 218 + L V+F+VFGLG++ Y HF A G VD LE+LG +RI ++ GD+ EE F T Sbjct: 129 STGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRT 188 Query: 219 WREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQK--PPF 276 W ++ + A C+ F V +D+++ K + +S++ K + Sbjct: 189 WAKKVFKAACDVF----------------CVGDDVNIEKPNNSLISNDRSWKRNKFRLTY 232 Query: 277 DAKNPFLAA---------VTANRKLNQ------GTERHLMHLELDIS-DSKIRYESGDHV 320 A+ P L V+A R L++ + R + + L + + +++Y+ GDH+ Sbjct: 233 VAEAPDLTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHL 292 Query: 321 AVYPANDSALVNQIGEIL--GADLDVIMSLNNLDEESN--------KKHPFPCPTTYRTA 370 V+P N LVN + E L + ++ + L+E + K P T A Sbjct: 293 GVFPGNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQA 352 Query: 371 LTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAI 430 YYLDIT PP L + A A+ E++ L ++ +G + Y W ++ + Sbjct: 353 FKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLS----KGLQEYEEWKWGKNPTMVEV 408 Query: 431 LQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGR--VNKG 488 L+++PS++ P L L LQ RYYSI+SS ++P+ VH+ V Y + G V+ G Sbjct: 409 LEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHG 468 Query: 489 VATSWLRAKEPAGENGGRALVPMFVRKS-QFRLPFKSTTPVIMVGPGTGIAPFMGFIQER 547 V +SWL + +VP FVR + F LP P I+VGPGTGIAPF F Q+R Sbjct: 469 VCSSWLNRIQ------ADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQR 522 Query: 548 AW-LREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAH-KVYV 605 + ++ +G +L +GCR+S D++YREE + G +L A+SRE K YV Sbjct: 523 QFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYV 582 Query: 606 QHLLKRD-REHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVK 664 Q +L+ E +++ + E G HIYVCGD MA DV I+ + G + A ++ Sbjct: 583 QDVLQEQLAESVYRALKEQGGHIYVCGDV-TMAADVLKAIQRIMTQQGKLSEEDAGVFIS 641 Query: 665 KLMTKGRYSLDVW 677 +L RY D++ Sbjct: 642 RLRDDNRYHEDIF 654 >6EFV-A nrPDB Length = 569 Score = 245 bits (625), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 188/614 (30%), Positives = 290/614 (47%), Gaps = 100/614 (16%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I + SQTG A A L D + + +Y ++S + L++ +T Sbjct: 40 ITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIAS-----EKLLIVVTST 94 Query: 140 YGEGDPTDNAQDFYDWL-QETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQ 198 GEG+P + A + +L + L FAVF LG+ +YE F GK D +L +LG + Sbjct: 95 QGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGE 154 Query: 199 RIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKV 258 R+ L D D + WR + A+ V ATG V ++ Sbjct: 155 RL--LDRVDADVEYQAAASEWRARVVDALKSRAPVVATGA----------------VNEI 196 Query: 259 YTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLN-QGTERHLMHLELDISDSKIRYESG 317 +T P+ P +A+++ N+K+ + +E+ + H+E+D+ DS +RY+ G Sbjct: 197 HTS-------------PYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPG 243 Query: 318 DHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDI 377 D + V+ ND ALV ++ E+L D +++ K P AL ++ ++ Sbjct: 244 DALGVWYQNDPALVKELVELLWLKGDEPVTV------EGKTLPL------NEALQWHFEL 291 Query: 378 TNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSL 437 T N + YA+ + L + A LQ Y + Sbjct: 292 T----VNTANIVENYATLTRSETLLPLVGDK--------------------AKLQHYAAT 327 Query: 438 RPPIDH------------LCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRV 485 P +D L LL L R YSIASS N VH+ V Y+ + GR Sbjct: 328 TPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVE-GRA 386 Query: 486 NKGVATSWLRAK-EPAGENGGRALVPMFVRKS-QFRLPFKSTTPVIMVGPGTGIAPFMGF 543 G A+S+L + E GE V +F+ + FRLP TPVIM+GPGTGIAPF F Sbjct: 387 RAGGASSFLADRVEEEGE------VRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAF 440 Query: 544 IQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKV 603 +Q+RA + G+ L++G ED+LY+ E R+ K+G LT++++A+SR+Q KV Sbjct: 441 MQQRA----ADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKV 496 Query: 604 YVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYV 663 YVQ L+ LW+ I++G AHIYVCGDA MAKDV+ +++AEFG M+ A +++ Sbjct: 497 YVQDKLREQGAELWRWINDG-AHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFL 555 Query: 664 KKLMTKGRYSLDVW 677 +L + RY DV+ Sbjct: 556 SELRVERRYQRDVY 569 >1BVY-F nrPDB Length = 191 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 56/184 (30%), Positives = 88/184 (47%), Gaps = 15/184 (8%) Query: 63 PVKESSFVEKMKKTGRN-----IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEY 117 P E S +K++K N ++V YGS GTAE A L+ A G A + + Sbjct: 3 PSTEQS-AKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSH 61 Query: 118 DLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVD-LTGVKFAVFGLGNK 176 +LP + V+ A+Y G P DNA+ F DWL + D + GV+++VFG G+K Sbjct: 62 ----AGNLPR--EGAVLIVTASY-NGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDK 114 Query: 177 TYEH-FNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA 235 + + + ++D+ L GA+ I + G D + E + WRE W V +F ++ Sbjct: 115 NWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDI 174 Query: 236 TGEE 239 E Sbjct: 175 ENSE 178 >4H2D-A nrPDB Length = 165 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 52/153 (33%), Positives = 83/153 (54%), Gaps = 10/153 (6%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 ++V +GSQTGTA++ + RL ++A R + + Y + +L I++ LV+F AT Sbjct: 10 LLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNL-----INEPLVIFVCAT 64 Query: 140 YGEGDPTDNAQDFYDWLQETDVDLTGV---KFAVFGLGNKTYEHFNAMGKYVDQRLEQLG 196 G+GDP DN ++F+ ++ ++ T + FAV GLG+ +Y FN + K + +RL QLG Sbjct: 65 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 124 Query: 197 AQRIFELGLGDDDGNLEEDFIT--WREQFWPAV 227 + + LGDD L D W W V Sbjct: 125 GSALLPVCLGDDQHELGPDAAVDPWLRDLWDRV 157 >3HR4-A nrPDB Length = 219 Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 15/194 (7%) Query: 45 RKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGR-NIIVFYGSQTGTAEEFANRLSKDAH 103 R K+ EIP ++ V + + + R + + + ++TG +E A L Sbjct: 11 RPKRREIP----LKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLG---- 62 Query: 104 RYGMRGMSADPEE--YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDV 161 + + +P+ D LS L E + L++ +T+G GD N + L Sbjct: 63 --ALFSCAFNPKVVCMDKYRLSCLEE--ERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKE 118 Query: 162 DLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWRE 221 ++AVFGLG+ Y F A +DQ+L LGA ++ +G GD+ E+ F +W Sbjct: 119 LNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAV 178 Query: 222 QFWPAVCEFFGVEA 235 Q + A CE F V Sbjct: 179 QTFKAACETFDVRG 192 >4OXX-A nrPDB Length = 162 Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 8/124 (6%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDK--SLVVFC 136 N ++ YG++TG AE A +S+ + + D + +DLAD++ +D L+VF Sbjct: 2 NALILYGTETGNAEACATTISQ------VLADTVDTKVHDLADMTPRAMLDSGADLIVFA 55 Query: 137 MATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLG 196 ATYGEG+ F++ L+ET DL+G++FAVFGLG+ Y FN G L LG Sbjct: 56 TATYGEGEFAGGGAAFFETLRETKPDLSGLRFAVFGLGDSYYTTFNQAGATAATILASLG 115 Query: 197 AQRI 200 ++ Sbjct: 116 GTQV 119 >2B5O-A nrPDB Length = 402 Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 59/205 (28%), Positives = 99/205 (48%), Gaps = 24/205 (11%) Query: 454 RYYSIASS--SKVHPN-SVHICAVAVEYE-AKSGRVNKGVATSWLRAKEPAGENGGRALV 509 R YSIAS+ + N +V +C +EY+ +SG GV +++L P G + + Sbjct: 179 RLYSIASTRHGDMEDNKTVSLCVRQLEYQDPESGETVYGVCSTYL-CNLPVGTDDVKITG 237 Query: 510 PMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAW--LREQGKEV---GETLLYY 564 P+ + LP V+M+ GTGIAPF F+ W +EQ ++ G+ L + Sbjct: 238 PV---GKEMLLPDDEDATVVMLATGTGIAPFRAFL----WRMFKEQHEDYKFKGKAWLIF 290 Query: 565 GCRRSDEDYLYREELARFHKDGALT-QLNVAFSREQ----AHKVYVQHLLKRDREHLWKL 619 G + + LY+++ + + +L A SREQ KVYVQ + + L+++ Sbjct: 291 GVPYT-ANILYKDDFEKMAAENPDNFRLTYAISREQKTADGGKVYVQSRVSEYADELFEM 349 Query: 620 IHEGGAHIYVCGDARNMAKDVQNTF 644 I + H+Y+CG + M + TF Sbjct: 350 IQKPNTHVYMCG-LKGMQPPIDETF 373 Score = 33.9 bits (76), Expect = 0.25, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 5/83 (6%) Query: 276 FDAKNPFLAAVTANRKL-NQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQI 334 + K PFL N +L ++G + H+ DIS+ +RY G + + P + ++ Sbjct: 117 YRPKTPFLGKCIENYELVDEGGSGTVRHVTFDISEGDLRYLEGQSIGIIPPGE----DKN 172 Query: 335 GEILGADLDVIMSLNNLDEESNK 357 G+ L I S + D E NK Sbjct: 173 GKPHKLRLYSIASTRHGDMEDNK 195 >1YKG-A nrPDB Length = 167 Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 6/124 (4%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I + SQTG A A L D + + +Y ++S + L++ +T Sbjct: 12 ITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIAS-----EKLLIVVTST 66 Query: 140 YGEGDPTDNAQDFYDWL-QETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQ 198 GEG+P + A + +L + L FAVF LG+ +YE F GK D +L +LG + Sbjct: 67 QGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGE 126 Query: 199 RIFE 202 R+ + Sbjct: 127 RLLD 130 >5VEG-A nrPDB Length = 178 Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 8/117 (6%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYG 141 V Y + TG EE AN + ++ ++ + D+AD + ++V C TY Sbjct: 35 VVYATMTGNNEEVANIVCDSLTNLNVKVTESEISQTDVADF-----MKADILVVCAYTYD 89 Query: 142 EGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTY-EHFNAMGKYVDQRLEQLGA 197 EG + DFYD LQ T DLTG + V G G+K Y E+FN + D ++ GA Sbjct: 90 EGAMPEEGLDFYDDLQST--DLTGKVYGVAGSGDKFYGEYFNTTVDHFDDAFKKAGA 144 >2HNA-A nrPDB Length = 147 Score = 52.4 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 8/138 (5%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 +I + GS G AE A L++ G E L LP LV+ + Sbjct: 3 DITLISGSTLGGAEYVAEHLAEKLEEAGF-----TTETLHGPLLEDLPASGIWLVI--SS 55 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQ 198 T+G GD DN FY+ LQE DL+ V+F G+G++ Y+ F ++ L+ GA+ Sbjct: 56 THGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAIDKLEAELKNSGAK 115 Query: 199 RIFE-LGLGDDDGNLEED 215 + E L + D ++ ED Sbjct: 116 QTGETLKINILDHDIPED 133 >6FSI-A nrPDB Length = 147 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 12/127 (9%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLAD---LSSLPEIDKSLVVF 135 +++ + S +G EE A+ ++ +R + E D+ D S L + D ++ Sbjct: 2 KLVMIFASMSGNTEEMADHIAG-----VIRETENEIEVIDIMDSPEASILEQYDG--IIL 54 Query: 136 CMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQL 195 T+G+GD D+ DFYD + +DLTG K AVFG + Y + + ++L++ Sbjct: 55 GAYTWGDGDLPDDFLDFYDAMDS--IDLTGKKAAVFGSCDSAYPKYGVAVDILIEKLQER 112 Query: 196 GAQRIFE 202 GA + E Sbjct: 113 GAAVVLE 119 >6GAQ-A nrPDB Length = 154 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 44/134 (32%), Positives = 65/134 (48%), Gaps = 27/134 (20%) Query: 79 NIIVFYGSQTGTAEEFAN--RLSKDAHRYG-----MRGMSADPEE---YDLADLSSLPEI 128 I++ Y S +G E A+ ++S DA + M GM D EE YD L S Sbjct: 10 KILIAYASMSGNTESIADLIKVSLDAFDHEVVLQEMEGM--DAEELLAYDGIILGSY--- 64 Query: 129 DKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYV 188 T+G+G+ A+DF+D L+ ++DL G K AVFG G+ YE F Sbjct: 65 ----------TWGDGELPFEAEDFHDDLE--NIDLAGKKVAVFGSGDTAYELFCEAVTIF 112 Query: 189 DQRLEQLGAQRIFE 202 ++RL + GA+ + E Sbjct: 113 EERLVERGAELVQE 126 >5LJI-A nrPDB Length = 148 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 9/142 (6%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYG 141 + + S TG EE A+ + A + G+ D +E D S E D ++V TYG Sbjct: 6 IVFASMTGNTEEIADIV---ADKLRDLGLDVDVDECTTVDASDFLEADIAIVA--TYTYG 60 Query: 142 EGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIF 201 +G+ D DFY+ L D++L G + V G G+ Y+ F D+ GA++ Sbjct: 61 DGELPDEMMDFYEDL--ADLNLNGKIYGVVGSGDTFYDEFCKAVDDFDRVFVSTGAEKGS 118 Query: 202 ELGLGDDDGNLEEDFITWREQF 223 E D + EE+ I EQF Sbjct: 119 E--CVKVDLSAEEEDIERLEQF 138 >2M6S-A nrPDB Length = 149 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 9/141 (6%) Query: 73 MKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSL 132 M + G + YG+ AEE L+ H+ + DPE D LP DK + Sbjct: 1 MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHK---ATVFEDPELSDW-----LPYQDKYV 52 Query: 133 VVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRL 192 +V +T G+GD D+ + ++++ +++ V LG+ +Y +F GK D L Sbjct: 53 LV-VTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCNGGKQFDALL 111 Query: 193 EQLGAQRIFELGLGDDDGNLE 213 ++ AQR+ E+ L D N E Sbjct: 112 QEQSAQRVGEMLLIDASENPE 132 >3F6S-A nrPDB Length = 148 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 42/148 (28%), Positives = 67/148 (45%), Gaps = 15/148 (10%) Query: 80 IIVFYGSQTGTAEEFANRLSK----DAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVF 135 +++ +GS TG E A +L + H + +AD +LAD V+F Sbjct: 4 VLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLN-AADASAENLAD-------GYDAVLF 55 Query: 136 CMATYGEGDPTDNAQDFYDWLQETD-VDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQ 194 + +G D + DF +E D + L G K A F G++ YEHF +++R ++ Sbjct: 56 GCSAWGMED-LEMQDDFLSLFEEFDRIGLAGRKVAAFASGDQEYEHFCGAVPAIEERAKE 114 Query: 195 LGAQRIFE-LGLGDDDGNLEEDFITWRE 221 LGA I E L + D N E ++ E Sbjct: 115 LGATIIAEGLKMEGDASNDPEAVASFAE 142 >5V57-A nrPDB Length = 648 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 11/152 (7%) Query: 72 KMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKS 131 +K ++ YGS TG E A ++++ G S D + L Sbjct: 371 SIKSNHAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFD 426 Query: 132 LVVFCMATYGEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYV 188 LV+ +T+G+ D + DF +D L+ET G K A FG G+ ++E+F + Sbjct: 427 LVLLGCSTWGD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAI 483 Query: 189 DQRLEQLGAQRIFE-LGLGDDDGNLEEDFITW 219 +++L+ LGA+ + + L + D +D + W Sbjct: 484 EEKLKNLGAEIVQDGLRIDGDPRAARDDIVGW 515 >5YOB-A nrPDB Length = 148 Score = 45.4 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 11/143 (7%) Query: 81 IVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATY 140 ++ YGS TG E A ++++ G S D + L LV+ +T+ Sbjct: 5 LIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFDLVLLGCSTW 60 Query: 141 GEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 G+ D + DF +D L+ET G K A FG G+ ++E+F ++++L+ LGA Sbjct: 61 GD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGA 117 Query: 198 QRIFE-LGLGDDDGNLEEDFITW 219 + + + L + D +D + W Sbjct: 118 EIVQDGLRIDGDPRAARDDIVGW 140 >5ZKP-A nrPDB Length = 466 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 11/153 (7%) Query: 81 IVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATY 140 ++ YGS TG E A ++++ G S D + L LV+ +T+ Sbjct: 222 LIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFDLVLLGCSTW 277 Query: 141 GEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 G+ D + DF +D L+ET G K A FG G+ ++E+F ++++L+ LGA Sbjct: 278 GD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGA 334 Query: 198 QRIFE-LGLGDDDGNLEEDFITWREQFWPAVCE 229 + + + L + D +D + W A+ E Sbjct: 335 EIVQDGLRIDGDPRAARDDIVGWAHDVRGAIAE 367 >5XRA-A nrPDB Length = 438 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 11/143 (7%) Query: 81 IVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATY 140 ++ YGS TG E A ++++ G S D + L LV+ +T+ Sbjct: 212 LIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFDLVLLGCSTW 267 Query: 141 GEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 G+ D + DF +D L+ET G K A FG G+ ++E+F ++++L+ LGA Sbjct: 268 GD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGA 324 Query: 198 QRIFE-LGLGDDDGNLEEDFITW 219 + + + L + D +D + W Sbjct: 325 EIVQDGLRIDGDPRAARDDIVGW 347 >4HEQ-A nrPDB Length = 146 Score = 42.4 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 32/120 (26%), Positives = 62/120 (51%), Gaps = 10/120 (8%) Query: 81 IVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDK--SLVVFCMA 138 ++ YGS TG E A ++K + GM + ++AD+++ P + + +V+ + Sbjct: 5 LIVYGSTTGNTEGVAEAIAKTLNSEGM-----ETTVVNVADVTA-PGLAEGYDVVLLGCS 58 Query: 139 TYGEGDPTDNAQDFYDWLQETD-VDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 T+G+ D + +DF ++ D L K VFG G+ +Y +F ++++ E+LGA Sbjct: 59 TWGD-DEIELQEDFVPLYEDLDRAGLKDKKVGVFGCGDSSYTYFCGAVDVIEKKAEELGA 117 >5B3K-A nrPDB Length = 150 Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust. Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 + + GS GTAEE A K G+ + A L L + + Sbjct: 2 KVAILSGSVYGTAEEVARHAQKLLSAAGL-----EASHLPRASLDELKAFAPEAFLVVTS 56 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTY-EHFNAMGKYVDQRLEQLGA 197 T G G+ DN Q Y +++ G+ V GLG+ +Y + F G+ V + +LG Sbjct: 57 TTGMGELPDNLQPLYYAIRDQLPAWHGLPGGVIGLGDSSYGDTFAGGGEQVRELFGELGV 116 Query: 198 QRIFEL 203 + + + Sbjct: 117 REVLPM 122 >5OGX-A nrPDB Length = 336 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 17/103 (16%) Query: 484 RVNKGVAT-SWLRAKEPAGENGGRALVPMFVRKSQFRLPFKS---TTPVIMVGPGTGIAP 539 RV GVAT WL AG+ A P+ F LP P++++G GTG+AP Sbjct: 167 RVPGGVATDGWLFDGLAAGDRV-EATGPL----GDFHLPPPDEDDGGPMVLIGGGTGLAP 221 Query: 540 FMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARF 582 +G I A R +EV LLY+G R + + Y +L RF Sbjct: 222 LVG-IARTALARHPSREV---LLYHGVRGAADLY----DLGRF 256 >1CZN-A nrPDB Length = 169 Score = 37.4 bits (85), Expect = 0.020, Method: Composition-based stats. Identities = 36/124 (29%), Positives = 64/124 (51%), Gaps = 12/124 (9%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I +FYG+QTG + A + ++ +G + D + AD S L D L++ C T Sbjct: 3 IGLFYGTQTGVTQTIAESIQQE---FGGESI-VDLNDIANADASDLNAYD-YLIIGC-PT 56 Query: 140 YGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKT--YEHF-NAMGKYVDQRLEQLG 196 + G+ + + YD L V+ G K A FG G++ ++F +AMG +++++ LG Sbjct: 57 WNVGELQSDWEGIYDDLDS--VNFQGKKVAYFGAGDQVGYSDNFQDAMG-ILEEKISSLG 113 Query: 197 AQRI 200 +Q + Sbjct: 114 SQTV 117 >3KAQ-A nrPDB Length = 147 Score = 35.8 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 +++ +GS TG E A +L + G + E A +L + ++++ C A Sbjct: 3 VLILFGSSTGNTESIAQKLEELVAAGGHEVTLLNAAE---ASADNLADGYDAVLMGCSA- 58 Query: 140 YGEGDP--TDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 +G D D+ +D ++ ++ L G K A F G+ YEH+ ++++ LGA Sbjct: 59 WGMEDLELQDDFAPLFDEME--NMGLKGKKLAAFASGDMEYEHYCGAVPAIEEKARGLGA 116 Query: 198 QRIFE 202 + I E Sbjct: 117 EVICE 121 >1WXQ-A nrPDB Length = 397 Score = 32.7 bits (73), Expect = 0.56, Method: Compositional matrix adjust. Identities = 46/241 (19%), Positives = 96/241 (39%), Gaps = 37/241 (15%) Query: 131 SLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQ 190 S ++ + G+ DP D++D +++ + + + ++G+ +K ++ F K Sbjct: 103 SALIHVVDATGKTDPEGQPTDYHDPVEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQKI 162 Query: 191 RLEQLGAQRIFELGLGDDDG-------NLEEDFITW------------REQFWPAVCEFF 231 +LE A+ + +G+ ++D NL ED W R P V Sbjct: 163 KLESAIAEHLSGIGVNENDVWEAMHKLNLPEDPTKWSQDDLLAFASEIRRVNKPMVIAAN 222 Query: 232 GVEATGEESSIRQYELVVHEDMDVAKVY--TGEMGRLKSYENQKPPFDAKNPFLAAVTAN 289 +A +E Q + +V E+ + T L + K F P + Sbjct: 223 KADAASDE----QIKRLVREEEKRGYIVIPTSAAAELTLRKAAKAGFIEYIPGASEFKVL 278 Query: 290 RKLNQGTERHLMHLELDISD-----------SKIRYESGDHVAVYPAND-SALVNQIGEI 337 R +++ +R LM ++ + D +++ ++ + VYP +D + L +Q G + Sbjct: 279 RDMSEKQKRALMVIKEKVLDRFGSTGVQEVINRVVFDLLKLIPVYPVHDENKLTDQFGNV 338 Query: 338 L 338 L Sbjct: 339 L 339 >2BMV-A nrPDB Length = 164 Score = 32.3 bits (72), Expect = 0.61, Method: Composition-based stats. Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 12/109 (11%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I +F+G+ +G AE A ++SK + E D+A S + V+ T Sbjct: 4 IGIFFGTDSGNAEAIAEKISKAI---------GNAEVVDVAKASKEQFNSFTKVILVAPT 54 Query: 140 YGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK-TYEHFNAMGKY 187 G GD + +DF L+ + D + GLG++ TY A G + Sbjct: 55 AGAGDLQTDWEDFLGTLEAS--DFANKTIGLVGLGDQDTYSETFAEGIF 101 >1KRH-A nrPDB Length = 338 Score = 32.3 bits (72), Expect = 0.66, Method: Compositional matrix adjust. Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 32/156 (20%) Query: 485 VNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKS------TTPVIMVGPGTGIA 538 V +G + +L + AG+ K F PF S PV+M+ GTGIA Sbjct: 176 VPQGKMSEYLSVQAKAGD------------KMSFTGPFGSFYLRDVKRPVLMLAGGTGIA 223 Query: 539 PFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSRE 598 PF+ +Q L ++G E L +G + D D + E+L + + + Sbjct: 224 PFLSMLQ---VLEQKGSE-HPVRLVFGVTQ-DCDLVALEQLDALQQKLPWFEYRTVVAHA 278 Query: 599 QAH---KVYVQHLLKRDREHLWKLIHEGGAHIYVCG 631 ++ K YV ++ D W ++ G +Y+CG Sbjct: 279 ESQHERKGYVTGHIEYD----W--LNGGEVDVYLCG 308 >1AG9-A nrPDB Length = 175 Score = 32.0 bits (71), Expect = 0.98, Method: Compositional matrix adjust. Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 36/148 (24%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDK------SLVVF 135 +F+GS TG E A + K + D+AD+ + + K +++ Sbjct: 5 IFFGSDTGNTENIAKMIQKQLGK-------------DVADVHDIAKSSKEDLEAYDILLL 51 Query: 136 CMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKT--YEHF-NAMGKYVDQRL 192 + T+ G+ + DF+ L+E +D G A+FG G++ E+F +A+G D + Sbjct: 52 GIPTWYYGEAQCDWDDFFPTLEE--IDFNGKLVALFGCGDQEDYAEYFCDALGTIRD-II 108 Query: 193 EQLGAQRI---------FEL--GLGDDD 209 E GA + FE GL DDD Sbjct: 109 EPRGATIVGHWPTAGYHFEASKGLADDD 136 >4V7I-AA nrPDB Length = 442 Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 23/37 (62%) Query: 48 KEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFY 84 K+ IP KI PVKE +F EK+K TG +++++ Sbjct: 1 KKLIPILEKIPEVELPVKEITFKEKLKWTGIVLVLYF 37 >2YXR-A nrPDB Length = 426 Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 23/37 (62%) Query: 48 KEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFY 84 K+ IP KI PVKE +F EK+K TG +++++ Sbjct: 2 KKLIPILEKIPEVELPVKEITFKEKLKWTGIVLVLYF 38 >2V5U-A nrPDB Length = 169 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 60/127 (47%), Gaps = 13/127 (10%) Query: 77 GRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSA-DPEEYDLADLSSLPEIDKSLVVF 135 + I +FYG+QTG E A + + +G ++ D + ++ DL+ + L++ Sbjct: 1 AKKIGLFYGTQTGKTESVAEIIRDE---FGNDVVTLHDVSQAEVTDLNDY----QYLIIG 53 Query: 136 CMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKT--YEHFNAMGKYVDQRLE 193 C T+ G+ + + Y L DVD G A FG G++ ++F +++++ Sbjct: 54 C-PTWNIGELQSDWEGLYSELD--DVDFNGKLVAYFGTGDQAGYADNFQDAIGILEEKIS 110 Query: 194 QLGAQRI 200 Q G + + Sbjct: 111 QRGGKTV 117 >2WC1-A nrPDB Length = 182 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 15/114 (13%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I +F+GS TGT + A ++ KD + A P + AD++ D ++ T Sbjct: 4 IGLFFGSDTGTTRKIAKQI-KDMFD---DEVMAKPLNVNRADVADFMAYD--FLILGTPT 57 Query: 140 YGEGD-PTDNAQDFYDWLQE-----TDVDLTGVKFAVFGLGNK-TY--EHFNAM 184 G+G P +A + +E D D +G A+FGLG++ TY E NA+ Sbjct: 58 LGDGQLPGLSANAASESWEEFLPRIADQDFSGKTIALFGLGDQVTYPLEFVNAL 111 >6BDE-A nrPDB Length = 185 Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 23/33 (69%), Gaps = 2/33 (6%) Query: 171 FGLG--NKTYEHFNAMGKYVDQRLEQLGAQRIF 201 FGLG NKT+EHFN+ + + +++++ G + F Sbjct: 142 FGLGLMNKTFEHFNSSAEIILEKIKEDGTEVKF 174 >1PQN-A nrPDB Length = 127 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 370 ALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILA 429 A+ Y +DIT P N +YEL + + H M G G ++W +E ++ ++ Sbjct: 55 AVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMI-DLGTGNNNKINWAMEDKQEMVD 113 Query: 430 ILQ 432 I++ Sbjct: 114 IIE 116 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3ES9-A nrPDB 994 0.0 6J79-A nrPDB 988 0.0 3QFR-A nrPDB 980 0.0 3FJO-A nrPDB 896 0.0 5GXU-A nrPDB 721 0.0 2BN4-A nrPDB 638 0.0 1TLL-A nrPDB 625 e-179 6EFV-A nrPDB 573 e-164 1B1C-A nrPDB 265 5e-71 2B5O-A nrPDB 214 9e-56 3HR4-A nrPDB 181 7e-46 5V57-A nrPDB 162 4e-40 5XRA-A nrPDB 159 4e-39 5ZKP-A nrPDB 158 9e-39 5YOB-A nrPDB 156 3e-38 1BVY-F nrPDB 153 3e-37 1YKG-A nrPDB 147 2e-35 5LJI-A nrPDB 133 2e-31 4H2D-A nrPDB 133 3e-31 4HEQ-A nrPDB 131 7e-31 2HNA-A nrPDB 131 9e-31 2M6S-A nrPDB 129 5e-30 3F6S-A nrPDB 128 9e-30 6GAQ-A nrPDB 125 5e-29 5VEG-A nrPDB 117 1e-26 4OXX-A nrPDB 116 4e-26 6FSI-A nrPDB 115 8e-26 Sequences not found previously or not previously below threshold: 3KAQ-A nrPDB 116 4e-26 5B3K-A nrPDB 93 3e-19 1AG9-A nrPDB 78 1e-14 2V5U-A nrPDB 73 6e-13 1CZN-A nrPDB 69 7e-12 2FCR-A nrPDB 64 2e-10 1FLA-A nrPDB 63 4e-10 2WC1-A nrPDB 61 1e-09 2BMV-A nrPDB 61 2e-09 2FZ5-A nrPDB 60 4e-09 1YOB-A nrPDB 59 6e-09 2MTB-A nrPDB 57 3e-08 1KRH-A nrPDB 52 1e-06 5OGX-A nrPDB 49 9e-06 3OZU-A nrPDB 44 1e-04 4EH1-A nrPDB 44 3e-04 2X2P-A nrPDB 43 4e-04 5WID-A nrPDB 42 0.001 3W2G-A nrPDB 41 0.002 2R6H-A nrPDB 41 0.002 6H0D-A nrPDB 40 0.003 1UMK-A nrPDB 40 0.004 5THX-A nrPDB 39 0.005 6O0A-A nrPDB 38 0.011 4N82-B nrPDB 37 0.021 4B4D-A nrPDB 37 0.030 1A8P-A nrPDB 36 0.049 2VNH-A nrPDB 36 0.051 4DIK-A nrPDB 35 0.14 1TLB-A nrPDB 34 0.23 4U9U-A nrPDB 34 0.26 4P6V-F nrPDB 34 0.26 6G70-A nrPDB 34 0.31 4G1B-A nrPDB 33 0.33 1IQV-A nrPDB 33 0.34 1GVH-A nrPDB 33 0.38 2ARK-A nrPDB 33 0.43 2QDX-A nrPDB 33 0.44 1TK1-A nrPDB 32 0.80 3GZX-A nrPDB 32 1.1 3J0A-A nrPDB 31 1.3 1RLJ-A nrPDB 31 1.3 4FK8-A nrPDB 31 1.5 6C2V-A nrPDB 31 1.6 4C5O-A nrPDB 31 1.7 1P35-A nrPDB 31 1.8 1CI3-M nrPDB 31 1.8 3FPK-A nrPDB 31 2.0 2EIX-A nrPDB 31 2.5 5MWL-A nrPDB 30 3.5 3TC1-A nrPDB 29 8.9 >3ES9-A nrPDB Length = 618 Score = 994 bits (2570), Expect = 0.0, Method: Composition-based stats. Identities = 618/622 (99%), Positives = 618/622 (99%), Gaps = 4/622 (0%) Query: 57 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 116 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE Sbjct: 1 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 60 Query: 117 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 176 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK Sbjct: 61 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 120 Query: 177 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEAT 236 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA Sbjct: 121 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA- 179 Query: 237 GEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 296 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT Sbjct: 180 ---SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 236 Query: 297 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 356 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN Sbjct: 237 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 296 Query: 357 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 416 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY Sbjct: 297 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 356 Query: 417 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 476 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV Sbjct: 357 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 416 Query: 477 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 536 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG Sbjct: 417 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 476 Query: 537 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 596 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS Sbjct: 477 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 536 Query: 597 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 656 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH Sbjct: 537 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 596 Query: 657 TQAVDYVKKLMTKGRYSLDVWS 678 TQAVDYVKKLMTKGRYSLDVWS Sbjct: 597 TQAVDYVKKLMTKGRYSLDVWS 618 >6J79-A nrPDB Length = 871 Score = 988 bits (2555), Expect = 0.0, Method: Composition-based stats. Identities = 617/622 (99%), Positives = 618/622 (99%), Gaps = 4/622 (0%) Query: 57 IQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 116 +QTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE Sbjct: 254 MQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEE 313 Query: 117 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 176 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK Sbjct: 314 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK 373 Query: 177 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEAT 236 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA Sbjct: 374 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA- 432 Query: 237 GEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 296 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT Sbjct: 433 ---SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGT 489 Query: 297 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 356 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN Sbjct: 490 ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESN 549 Query: 357 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 416 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY Sbjct: 550 KKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELY 609 Query: 417 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 476 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV Sbjct: 610 LSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAV 669 Query: 477 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 536 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG Sbjct: 670 EYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTG 729 Query: 537 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 596 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS Sbjct: 730 IAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFS 789 Query: 597 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 656 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH Sbjct: 790 REQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEH 849 Query: 657 TQAVDYVKKLMTKGRYSLDVWS 678 TQAVDYVKKLMTKGRYSLDVWS Sbjct: 850 TQAVDYVKKLMTKGRYSLDVWS 871 >3QFR-A nrPDB Length = 618 Score = 980 bits (2534), Expect = 0.0, Method: Composition-based stats. Identities = 577/615 (93%), Positives = 599/615 (97%), Gaps = 1/615 (0%) Query: 64 VKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 123 V+ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS Sbjct: 5 VRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 64 Query: 124 SLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNA 183 SLPEID +LVVFCMATYGEGDPTDNAQDFYDWLQETDVDL+GVKFAVFGLGNKTYEHFNA Sbjct: 65 SLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNA 124 Query: 184 MGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIR 243 MGKYVD+RLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCE FGVEATGEESSIR Sbjct: 125 MGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESSIR 184 Query: 244 QYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHL 303 QYELVVH D+D AKVY GEMGRLKSYENQKPPFDAKNPFLAAVT NRKLNQGTERHLMHL Sbjct: 185 QYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHL 244 Query: 304 ELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPC 363 ELDISDSKIRYESGDHVAVYPANDSALVNQ+G+ILGADLDV+MSLNNLDEESNKKHPFPC Sbjct: 245 ELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPC 304 Query: 364 PTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEA 423 PT+YRTALTYYLDITNPPRTNVLYELAQYASEPSEQE L KMASSSGEGKELYLSWVVEA Sbjct: 305 PTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEA 364 Query: 424 RRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSG 483 RRHILAILQD PSLRPPIDHLCELLPRLQA YYSIASSSKVHPNSVHICAV VEYE K+G Sbjct: 365 RRHILAILQDCPSLRPPIDHLCELLPRLQAHYYSIASSSKVHPNSVHICAVVVEYETKAG 424 Query: 484 RVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGF 543 R+NKGVAT+WLRAKEPAGENGGRALVPMFVRKSQFRLPFK+TTPVIMVGPGTG+APF+GF Sbjct: 425 RINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGF 484 Query: 544 IQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKV 603 IQERAWLR+QGKEVGETLLYYGCRRSDEDYLYREELA+FH+DGALTQLNVAFSREQ+HKV Sbjct: 485 IQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKV 544 Query: 604 YVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYV 663 YVQHLLK+DREHLWKLI EGGAHIYVCGDARNMA+DVQNTFYDIVAE G MEH QAVDY+ Sbjct: 545 YVQHLLKQDREHLWKLI-EGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYI 603 Query: 664 KKLMTKGRYSLDVWS 678 KKLMTKGRYSLDVWS Sbjct: 604 KKLMTKGRYSLDVWS 618 >3FJO-A nrPDB Length = 637 Score = 896 bits (2314), Expect = 0.0, Method: Composition-based stats. Identities = 472/613 (76%), Positives = 527/613 (85%), Gaps = 8/613 (1%) Query: 69 FVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDA-HRYGMRGMSADPEEYDLADLSSLPE 127 + + + +N +V Y SQTGTAE++A + SK+ ++ + M AD E YD L+ +P Sbjct: 30 IAQVVTENNKNYLVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENYDFESLNDVPV 89 Query: 128 IDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVD-LTGVKFAVFGLGNKTYEHFNAMGK 186 +V ++TYGEGD D A +F D++ + L+ +++ +FGLGN TYE FN K Sbjct: 90 ----IVSIFISTYGEGDFPDGAVNFEDFICNAEAGALSNLRYNMFGLGNSTYEFFNGAAK 145 Query: 187 YVDQRLEQLGAQRIFELGLGDDD-GNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQY 245 ++ L GA R+ +LG DD G +ED++ W++ + + GVEATGEESSIRQY Sbjct: 146 KAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELGVEATGEESSIRQY 205 Query: 246 ELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLEL 305 ELVVH D+D AKVY GEMGRLKSYENQKPPFDAKNPFLAAVT NRKLNQGTERHLMHLEL Sbjct: 206 ELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLEL 265 Query: 306 DISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPT 365 DISDSKIRYESGDHVAVYPANDSALVNQ+G+ILGADLDV+MSLNNLDEESNKKHPFPCPT Sbjct: 266 DISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPT 325 Query: 366 TYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARR 425 +YRTALTYYLDITNPPRTNVLYELAQYASEPSEQE L KMASSSGEGKELYLSWVVEARR Sbjct: 326 SYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARR 385 Query: 426 HILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRV 485 HILAILQD PSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAV VEYE K+GR+ Sbjct: 386 HILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRI 445 Query: 486 NKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQ 545 NKGVAT+WLRAKEPAGENGGRALVPMFVRKSQFRLPFK+TTPVIMVGPGTG+APF+GFIQ Sbjct: 446 NKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQ 505 Query: 546 ERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYV 605 ERAWLR+QGKEVGETLLYYGCRRSDEDYLYREELA+FH+DGALTQLNVAFSREQ+HKVYV Sbjct: 506 ERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKVYV 565 Query: 606 QHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKK 665 QHLLK+DREHLWKLI EGGAHIYVCGDARNMA+DVQNTFYDIVAE G MEH QAVDY+KK Sbjct: 566 QHLLKQDREHLWKLI-EGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKK 624 Query: 666 LMTKGRYSLDVWS 678 LMTKGRYSLDVWS Sbjct: 625 LMTKGRYSLDVWS 637 >5GXU-A nrPDB Length = 640 Score = 721 bits (1862), Expect = 0.0, Method: Composition-based stats. Identities = 248/633 (39%), Positives = 366/633 (57%), Gaps = 25/633 (3%) Query: 62 PPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRY--GMRGMSADPEEYDL 119 P+ E++ + + +F+G+QTGTAE FA L ++A R D ++Y Sbjct: 16 KPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAA 75 Query: 120 ADLSSLPEIDKSLVVFC-MATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGLGN 175 D ++ K V F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN Sbjct: 76 DDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGN 135 Query: 176 KTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVE- 234 + YEHFN + K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E Sbjct: 136 RQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEG 195 Query: 235 ----ATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANR 290 AT +++ +Y + +H+ D AK M Y FDA++P+ A V R Sbjct: 196 DTAVATPYTAAVLEYRVSIHDSED-AKFNDINMANGNGYT----VFDAQHPYKANVAVKR 250 Query: 291 KLNQG-TERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLN 349 +L+ ++R +HLE DI+ S + YE+GDHV V N S V++ +L D SL+ Sbjct: 251 ELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLH 310 Query: 350 NLDEESNKKHPFPCP----TTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKM 405 E+ P RTALT Y + + P+ + L LA +AS+P+E E L + Sbjct: 311 AEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHL 370 Query: 406 ASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKV 464 AS + GK+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ Sbjct: 371 ASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKI 428 Query: 465 HPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKS 524 +H+ V + +GR++KGV ++W++ P ++ + P+FVR+S F+LP S Sbjct: 429 AETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDS 488 Query: 525 TTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHK 584 P+IM+GPGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF + Sbjct: 489 KVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVE 548 Query: 585 DGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTF 644 GAL +L+VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV + Sbjct: 549 SGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSL 607 Query: 645 YDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVW 677 + I E G M+ T+A +VK L T GRY DVW Sbjct: 608 HTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 640 >2BN4-A nrPDB Length = 682 Score = 638 bits (1644), Expect = 0.0, Method: Composition-based stats. Identities = 224/669 (33%), Positives = 339/669 (50%), Gaps = 67/669 (10%) Query: 59 TTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDA-HRYGMRGMSADPEEY 117 TA + + + +N +V Y SQTGTAE++A + SK+ ++ + M AD E Y Sbjct: 31 ITAVSSGNRDIAQVVTENNKNYLVLYASQTGTAEDYAKKFSKELVAKFNLNVMCADVENY 90 Query: 118 DLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVD-LTGVKFAVFGLGNK 176 D L+ +P +V ++TYGEGD D A +F D++ + L+ +++ +FGLGN Sbjct: 91 DFESLNDVPV----IVSIFISTYGEGDFPDGAVNFEDFICNAEAGALSNLRYNMFGLGNS 146 Query: 177 TYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDD-GNLEEDFITWREQFWPAVCEFFGV-E 234 TYE FN K ++ L GA R+ +LG DD G +ED++ W++ + + + E Sbjct: 147 TYEFFNGAAKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDE 206 Query: 235 ATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYE-------NQKPPFDAKNPFLAAVT 287 + +S QY V++E D + L S++ Q PFD P++A + Sbjct: 207 QEAKFTSQFQYT-VLNEITDSMSLGEPSAHYLPSHQLNRNADGIQLGPFDLSQPYIAPIV 265 Query: 288 ANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMS 347 +R+L +R+ +H E D+S S I+Y +GDH+AV+P+N V Q I D + I Sbjct: 266 KSRELFSSNDRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLSIFNLDPETIFD 325 Query: 348 LNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMAS 407 L LD K PFP PTT A+ +YL+IT P + L Q+A +E L ++ Sbjct: 326 LKPLD--PTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLLSK 383 Query: 408 SSGEGKELYLSWVVEARRHILAILQDYPSLRP-------PIDHLCELLPRLQARYYSIAS 460 + + VE I L P+ L E +P++ RYYSI+S Sbjct: 384 DKDQ-------FAVEITSKYFNIADALKYLSDGAKWDTVPMQFLVESVPQMTPRYYSISS 436 Query: 461 SSKVHPNSVHICAVAVEY---EAKSGRVNKGVATSWLRAKEPAGE--------------- 502 SS +VH+ ++ + E GV T+ LR + A Sbjct: 437 SSLSEKQTVHVTSIVENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDL 496 Query: 503 NGGRAL-----VPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQER-AWLREQGK- 555 NG R L +P+ VR+S FRLP +TPVIM+GPGTG+APF GFI+ER A+L Q K Sbjct: 497 NGPRKLFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKG 556 Query: 556 ----EVGETLLYYGCRRSDEDYLYREELARFHK--DGALTQLNVAFSR-EQAHKVYVQHL 608 +G+ +L+YG R +D D+LY++E + K DG+ ++ VA SR KVYVQ Sbjct: 557 GNNVSLGKHILFYGSRNTD-DFLYQDEWPEYAKKLDGSF-EMVVAHSRLPNTKKVYVQDK 614 Query: 609 LKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMT 668 LK + ++++I+ GA IYVCGDA+ MAK V I++ + +A + +K L T Sbjct: 615 LKDYEDQVFEMINN-GAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKT 673 Query: 669 KGRYSLDVW 677 GRY DVW Sbjct: 674 SGRYQEDVW 682 >1TLL-A nrPDB Length = 688 Score = 625 bits (1611), Expect = e-179, Method: Composition-based stats. Identities = 193/678 (28%), Positives = 310/678 (45%), Gaps = 109/678 (16%) Query: 76 TGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVF 135 + Y ++TG ++ +A L + ++ + EEYD+ L ++LV+ Sbjct: 10 KRVKATILYATETGKSQAYAKTLCEI-FKHAFDAKAMSMEEYDIVHLEH-----EALVLV 63 Query: 136 CMATYGEGDPTDNAQDFYDWL--------------------------------------- 156 +T+G GDP +N + F L Sbjct: 64 VTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSRKSSGDGPDL 123 Query: 157 ---QETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLE 213 E+ L V+F+VFGLG++ Y HF A G VD LE+LG +RI ++ GD+ E Sbjct: 124 RDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQE 183 Query: 214 EDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQK 273 E F TW ++ + A C+ F V +D+++ K + +S++ K Sbjct: 184 EAFRTWAKKVFKAACDVF----------------CVGDDVNIEKPNNSLISNDRSWKRNK 227 Query: 274 --PPFDAKNPFLAA---------VTANRKLNQ------GTERHLMHLELDISD-SKIRYE 315 + A+ P L V+A R L++ + R + + L + +++Y+ Sbjct: 228 FRLTYVAEAPDLTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQ 287 Query: 316 SGDHVAVYPANDSALVNQIGEIL--GADLDVIMSLNNLDEESN--------KKHPFPCPT 365 GDH+ V+P N LVN + E L + ++ + L+E + K P Sbjct: 288 PGDHLGVFPGNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPC 347 Query: 366 TYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARR 425 T A YYLDIT PP L + A A+ E++ L ++ +G + Y W Sbjct: 348 TIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLS----KGLQEYEEWKWGKNP 403 Query: 426 HILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGR- 484 ++ +L+++PS++ P L L LQ RYYSI+SS ++P+ VH+ V Y + G Sbjct: 404 TMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEG 463 Query: 485 -VNKGVATSWLRAKEPAGENGGRALVPMFVRKS-QFRLPFKSTTPVIMVGPGTGIAPFMG 542 V+ GV +SWL + +VP FVR + F LP P I+VGPGTGIAPF Sbjct: 464 PVHHGVCSSWLNRIQ------ADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRS 517 Query: 543 FIQERAW-LREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAH 601 F Q+R + ++ +G +L +GCR+S D++YREE + G +L A+SRE Sbjct: 518 FWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDR 577 Query: 602 -KVYVQHLLKRD-REHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQA 659 K YVQ +L+ E +++ + E G HIYVCGD MA DV I+ + G + A Sbjct: 578 PKKYVQDVLQEQLAESVYRALKEQGGHIYVCGDV-TMAADVLKAIQRIMTQQGKLSEEDA 636 Query: 660 VDYVKKLMTKGRYSLDVW 677 ++ +L RY D++ Sbjct: 637 GVFISRLRDDNRYHEDIF 654 >6EFV-A nrPDB Length = 569 Score = 573 bits (1476), Expect = e-164, Method: Composition-based stats. Identities = 184/613 (30%), Positives = 286/613 (46%), Gaps = 98/613 (15%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I + SQTG A A L D + + +Y ++S + L++ +T Sbjct: 40 ITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIAS-----EKLLIVVTST 94 Query: 140 YGEGDPTDNAQDFYDWLQETD-VDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQ 198 GEG+P + A + +L L FAVF LG+ +YE F GK D +L +LG + Sbjct: 95 QGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGE 154 Query: 199 RIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKV 258 R+ + D D + WR + A+ V ATG V ++ Sbjct: 155 RLLDR--VDADVEYQAAASEWRARVVDALKSRAPVVATGA----------------VNEI 196 Query: 259 YTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLN-QGTERHLMHLELDISDSKIRYESG 317 +T P+ P +A+++ N+K+ + +E+ + H+E+D+ DS +RY+ G Sbjct: 197 HTS-------------PYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPG 243 Query: 318 DHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDI 377 D + V+ ND ALV ++ E+L D +++ K P AL ++ ++ Sbjct: 244 DALGVWYQNDPALVKELVELLWLKGDEPVTVE------GKTLP------LNEALQWHFEL 291 Query: 378 TNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSL 437 T N + YA+ + L + A LQ Y + Sbjct: 292 T----VNTANIVENYATLTRSETLLPLVGDK--------------------AKLQHYAAT 327 Query: 438 RPPIDH------------LCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRV 485 P +D L LL L R YSIASS N VH+ V Y+ + GR Sbjct: 328 TPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVE-GRA 386 Query: 486 NKGVATSWLRAKEPAGENGGRALVPMFVRKS-QFRLPFKSTTPVIMVGPGTGIAPFMGFI 544 G A+S+L + V +F+ + FRLP TPVIM+GPGTGIAPF F+ Sbjct: 387 RAGGASSFLADRVEEEGE-----VRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFM 441 Query: 545 QERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVY 604 Q+RA + G+ L++G ED+LY+ E R+ K+G LT++++A+SR+Q KVY Sbjct: 442 QQRA----ADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVY 497 Query: 605 VQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVK 664 VQ L+ LW+ I++ GAHIYVCGDA MAKDV+ +++AEFG M+ A +++ Sbjct: 498 VQDKLREQGAELWRWIND-GAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLS 556 Query: 665 KLMTKGRYSLDVW 677 +L + RY DV+ Sbjct: 557 ELRVERRYQRDVY 569 >1B1C-A nrPDB Length = 181 Score = 265 bits (677), Expect = 5e-71, Method: Composition-based stats. Identities = 172/178 (96%), Positives = 176/178 (98%) Query: 64 VKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 123 V+ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS Sbjct: 4 VRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLS 63 Query: 124 SLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNA 183 SLPEID +LVVFCMATYGEGDPTDNAQDFYDWLQETDVDL+GVKFAVFGLGNKTYEHFNA Sbjct: 64 SLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNA 123 Query: 184 MGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESS 241 MGKYVD+RLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCE FGVEATGEESS Sbjct: 124 MGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESS 181 >2B5O-A nrPDB Length = 402 Score = 214 bits (545), Expect = 9e-56, Method: Composition-based stats. Identities = 62/236 (26%), Positives = 111/236 (47%), Gaps = 24/236 (10%) Query: 454 RYYSIASS--SKVHPN-SVHICAVAVEYE-AKSGRVNKGVATSWLRAKEPAGENGGRALV 509 R YSIAS+ + N +V +C +EY+ +SG GV +++L P G + + Sbjct: 179 RLYSIASTRHGDMEDNKTVSLCVRQLEYQDPESGETVYGVCSTYL-CNLPVGTDDVKITG 237 Query: 510 PMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEV---GETLLYYGC 566 P+ + LP V+M+ GTGIAPF F+ +EQ ++ G+ L +G Sbjct: 238 PV---GKEMLLPDDEDATVVMLATGTGIAPFRAFLWR--MFKEQHEDYKFKGKAWLIFGV 292 Query: 567 RRSDEDYLYREELARFHKDGALT-QLNVAFSREQ----AHKVYVQHLLKRDREHLWKLIH 621 + + LY+++ + + +L A SREQ KVYVQ + + L+++I Sbjct: 293 PYT-ANILYKDDFEKMAAENPDNFRLTYAISREQKTADGGKVYVQSRVSEYADELFEMIQ 351 Query: 622 EGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVW 677 + H+Y+CG + M + TF AE + + + + + R+ ++V+ Sbjct: 352 KPNTHVYMCG-LKGMQPPIDETF-TAEAEKRGLNWE---EMRRSMKKEHRWHVEVY 402 Score = 35.2 bits (79), Expect = 0.087, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 5/87 (5%) Query: 276 FDAKNPFLAAVTANRKL-NQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQI 334 + K PFL N +L ++G + H+ DIS+ +RY G + + P + ++ Sbjct: 117 YRPKTPFLGKCIENYELVDEGGSGTVRHVTFDISEGDLRYLEGQSIGIIPPGE----DKN 172 Query: 335 GEILGADLDVIMSLNNLDEESNKKHPF 361 G+ L I S + D E NK Sbjct: 173 GKPHKLRLYSIASTRHGDMEDNKTVSL 199 >3HR4-A nrPDB Length = 219 Score = 181 bits (460), Expect = 7e-46, Method: Composition-based stats. Identities = 55/211 (26%), Positives = 90/211 (42%), Gaps = 15/211 (7%) Query: 45 RKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGR-NIIVFYGSQTGTAEEFANRLSKDAH 103 R K+ EIP ++ V + + + R + + + ++TG +E A L Sbjct: 11 RPKRREIP----LKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLG---- 62 Query: 104 RYGMRGMSADPEE--YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDV 161 + + +P+ D LS L E + L++ +T+G GD N + L Sbjct: 63 --ALFSCAFNPKVVCMDKYRLSCLEE--ERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKE 118 Query: 162 DLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWRE 221 ++AVFGLG+ Y F A +DQ+L LGA ++ +G GD+ E+ F +W Sbjct: 119 LNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAV 178 Query: 222 QFWPAVCEFFGVEATGEESSIRQYELVVHED 252 Q + A CE F V + Y V D Sbjct: 179 QTFKAACETFDVRGKQHIQIPKLYTSNVTWD 209 >5V57-A nrPDB Length = 648 Score = 162 bits (410), Expect = 4e-40, Method: Composition-based stats. Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 11/161 (6%) Query: 72 KMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKS 131 +K ++ YGS TG E A ++++ G S D + L Sbjct: 371 SIKSNHAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFD 426 Query: 132 LVVFCMATYGEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYV 188 LV+ +T+G+ D + DF +D L+ET G K A FG G+ ++E+F + Sbjct: 427 LVLLGCSTWGD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAI 483 Query: 189 DQRLEQLGAQRIFE-LGLGDDDGNLEEDFITWREQFWPAVC 228 +++L+ LGA+ + + L + D +D + W A+ Sbjct: 484 EEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIK 524 >5XRA-A nrPDB Length = 438 Score = 159 bits (401), Expect = 4e-39, Method: Composition-based stats. Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 11/167 (6%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 ++ YGS TG E A ++++ G S D + L LV+ Sbjct: 209 AKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFDLVLLGC 264 Query: 138 ATYGEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQ 194 +T+G+ D + DF +D L+ET G K A FG G+ ++E+F ++++L+ Sbjct: 265 STWGD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAIEEKLKN 321 Query: 195 LGAQRIFE-LGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEES 240 LGA+ + + L + D +D + W A+ + ++ ++ Sbjct: 322 LGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIPDQARMDIELAKT 368 >5ZKP-A nrPDB Length = 466 Score = 158 bits (399), Expect = 9e-39, Method: Composition-based stats. Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 11/157 (7%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 ++ YGS TG E A ++++ G S D + L LV+ Sbjct: 219 AKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFDLVLLGC 274 Query: 138 ATYGEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQ 194 +T+G+ D + DF +D L+ET G K A FG G+ ++E+F ++++L+ Sbjct: 275 STWGD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAIEEKLKN 331 Query: 195 LGAQRIFE-LGLGDDDGNLEEDFITWREQFWPAVCEF 230 LGA+ + + L + D +D + W A+ E Sbjct: 332 LGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIAEV 368 >5YOB-A nrPDB Length = 148 Score = 156 bits (393), Expect = 3e-38, Method: Composition-based stats. Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 11/155 (7%) Query: 77 GRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFC 136 ++ YGS TG E A ++++ G S D + L LV+ Sbjct: 1 SAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE----GFDLVLLG 56 Query: 137 MATYGEGDPTDNAQDF---YDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLE 193 +T+G+ D + DF +D L+ET G K A FG G+ ++E+F ++++L+ Sbjct: 57 CSTWGD-DSIELQDDFIPLFDSLEETGAQ--GRKVACFGCGDSSWEYFCGAVDAIEEKLK 113 Query: 194 QLGAQRIFE-LGLGDDDGNLEEDFITWREQFWPAV 227 LGA+ + + L + D +D + W A+ Sbjct: 114 NLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAI 148 >1BVY-F nrPDB Length = 191 Score = 153 bits (385), Expect = 3e-37, Method: Composition-based stats. Identities = 56/184 (30%), Positives = 88/184 (47%), Gaps = 15/184 (8%) Query: 63 PVKESSFVEKMKKTGRN-----IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEY 117 P E S +K++K N ++V YGS GTAE A L+ A G A + + Sbjct: 3 PSTEQS-AKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSH 61 Query: 118 DLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVD-LTGVKFAVFGLGNK 176 +LP + V+ A+Y G P DNA+ F DWL + D + GV+++VFG G+K Sbjct: 62 ----AGNLPR--EGAVLIVTASY-NGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDK 114 Query: 177 TY-EHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA 235 + + + ++D+ L GA+ I + G D + E + WRE W V +F ++ Sbjct: 115 NWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDI 174 Query: 236 TGEE 239 E Sbjct: 175 ENSE 178 >1YKG-A nrPDB Length = 167 Score = 147 bits (370), Expect = 2e-35, Method: Composition-based stats. Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 8/163 (4%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 I + SQTG A A L D + + +Y ++S + L++ +T Sbjct: 12 ITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIAS-----EKLLIVVTST 66 Query: 140 YGEGDPTDNAQDFYDWLQETD-VDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQ 198 GEG+P + A + +L L FAVF LG+ +YE F GK D +L +LG + Sbjct: 67 QGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGE 126 Query: 199 RIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESS 241 R+ + D D + WR + A+ V A + + Sbjct: 127 RLLDR--VDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVA 167 >5LJI-A nrPDB Length = 148 Score = 133 bits (335), Expect = 2e-31, Method: Composition-based stats. Identities = 43/151 (28%), Positives = 66/151 (43%), Gaps = 9/151 (5%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYG 141 + + S TG EE A+ ++ G+ D +E D S E D ++V TYG Sbjct: 6 IVFASMTGNTEEIADIVADKLRDLGL---DVDVDECTTVDASDFLEADIAIVA--TYTYG 60 Query: 142 EGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIF 201 +G+ D DFY+ L D++L G + V G G+ Y+ F D+ GA++ Sbjct: 61 DGELPDEMMDFYEDL--ADLNLNGKIYGVVGSGDTFYDEFCKAVDDFDRVFVSTGAEKGS 118 Query: 202 ELGLGDDDGNLEEDFITWREQFWPAVCEFFG 232 E D + EE+ I EQF + G Sbjct: 119 E--CVKVDLSAEEEDIERLEQFAEELAAKVG 147 >4H2D-A nrPDB Length = 165 Score = 133 bits (333), Expect = 3e-31, Method: Composition-based stats. Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 10/161 (6%) Query: 72 KMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKS 131 ++V +GSQTGTA++ + RL ++A R + + Y + +L I++ Sbjct: 2 SFTMPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNL-----INEP 56 Query: 132 LVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGV---KFAVFGLGNKTYEHFNAMGKYV 188 LV+F AT G+GDP DN ++F+ ++ ++ T + FAV GLG+ +Y FN + K + Sbjct: 57 LVIFVCATTGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKL 116 Query: 189 DQRLEQLGAQRIFELGLGDDDGNLEEDFIT--WREQFWPAV 227 +RL QLG + + LGDD L D W W V Sbjct: 117 HRRLLQLGGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRV 157 >4HEQ-A nrPDB Length = 146 Score = 131 bits (330), Expect = 7e-31, Method: Composition-based stats. Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 9/151 (5%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 ++ YGS TG E A ++K + GM + + L+ +V+ + Sbjct: 3 KALIVYGSTTGNTEGVAEAIAKTLNSEGMETTVVNVADVTAPGLAE----GYDVVLLGCS 58 Query: 139 TYGEGDPTDNAQDFYDWLQETD-VDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 T+G+ D + +DF ++ D L K VFG G+ +Y +F ++++ E+LGA Sbjct: 59 TWGD-DEIELQEDFVPLYEDLDRAGLKDKKVGVFGCGDSSYTYFCGAVDVIEKKAEELGA 117 Query: 198 QRIF-ELGLGDDDGNLEEDFITWREQFWPAV 227 + L + + + E + W + V Sbjct: 118 TLVASSLKIDGEPDSAE--VLDWAREVLARV 146 >2HNA-A nrPDB Length = 147 Score = 131 bits (330), Expect = 9e-31, Method: Composition-based stats. Identities = 43/145 (29%), Positives = 65/145 (44%), Gaps = 9/145 (6%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 +I + GS G AE A L++ G E L LP LV+ Sbjct: 2 ADITLISGSTLGGAEYVAEHLAEKLEEAGF-----TTETLHGPLLEDLPASGIWLVI--S 54 Query: 138 ATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 +T+G GD DN FY+ LQE DL+ V+F G+G++ Y+ F ++ L+ GA Sbjct: 55 STHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAIDKLEAELKNSGA 114 Query: 198 QRIFE-LGLGDDDGNLEED-FITWR 220 ++ E L + D ++ ED W Sbjct: 115 KQTGETLKINILDHDIPEDPAEEWL 139 >2M6S-A nrPDB Length = 149 Score = 129 bits (323), Expect = 5e-30, Method: Composition-based stats. Identities = 43/157 (27%), Positives = 71/157 (45%), Gaps = 12/157 (7%) Query: 73 MKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSL 132 M + G + YG+ AEE L+ H+ + DPE D LP DK Sbjct: 1 MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATV---FEDPELSDW-----LPYQDKY- 51 Query: 133 VVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRL 192 V+ +T G+GD D+ + ++++ +++ V LG+ +Y +F GK D L Sbjct: 52 VLVVTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCNGGKQFDALL 111 Query: 193 EQLGAQRIFELGLGDDDGNLEEDFIT--WREQFWPAV 227 ++ AQR+ E+ L D N E + + W E W + Sbjct: 112 QEQSAQRVGEMLLIDASENPEPETESNPWVEH-WGTL 147 >3F6S-A nrPDB Length = 148 Score = 128 bits (321), Expect = 9e-30, Method: Composition-based stats. Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 7/151 (4%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 +++ +GS TG E A +L + G + + +L+ V+F + Sbjct: 3 KVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLAD----GYDAVLFGCS 58 Query: 139 TYGEGDPTDNAQDFYDWLQETD-VDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 +G D + DF +E D + L G K A F G++ YEHF +++R ++LGA Sbjct: 59 AWGMEDL-EMQDDFLSLFEEFDRIGLAGRKVAAFASGDQEYEHFCGAVPAIEERAKELGA 117 Query: 198 QRIFE-LGLGDDDGNLEEDFITWREQFWPAV 227 I E L + D N E ++ E + Sbjct: 118 TIIAEGLKMEGDASNDPEAVASFAEDVLKQL 148 >6GAQ-A nrPDB Length = 154 Score = 125 bits (314), Expect = 5e-29, Method: Composition-based stats. Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 7/140 (5%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 I++ Y S +G E A+ + + + + E D +L + ++ Sbjct: 9 AKILIAYASMSGNTESIADLIKVSLDAFDHEVVLQEMEGMDAEEL-----LAYDGIILGS 63 Query: 138 ATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 T+G+G+ A+DF+D L+ ++DL G K AVFG G+ YE F ++RL + GA Sbjct: 64 YTWGDGELPFEAEDFHDDLE--NIDLAGKKVAVFGSGDTAYELFCEAVTIFEERLVERGA 121 Query: 198 QRIFELGLGDDDGNLEEDFI 217 + + E + EED Sbjct: 122 ELVQEGLKIELAPEDEEDVE 141 >5VEG-A nrPDB Length = 178 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 44/137 (32%), Positives = 63/137 (45%), Gaps = 9/137 (6%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYG 141 V Y + TG EE AN + ++ ++ + D+AD + ++V C TY Sbjct: 35 VVYATMTGNNEEVANIVCDSLTNLNVKVTESEISQTDVADF-----MKADILVVCAYTYD 89 Query: 142 EGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTY-EHFNAMGKYVDQRLEQLGAQRI 200 EG + DFYD LQ T DLTG + V G G+K Y E+FN + D ++ GA Sbjct: 90 EGAMPEEGLDFYDDLQST--DLTGKVYGVAGSGDKFYGEYFNTTVDHFDDAFKKAGATSG 147 Query: 201 FELGLGDDDGNLEEDFI 217 E + D EED Sbjct: 148 AE-KVKIDLEPYEEDIE 163 >4OXX-A nrPDB Length = 162 Score = 116 bits (290), Expect = 4e-26, Method: Composition-based stats. Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 10/155 (6%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDK--SLVVFC 136 N ++ YG++TG AE A +S+ + + D + +DLAD++ +D L+VF Sbjct: 2 NALILYGTETGNAEACATTISQ------VLADTVDTKVHDLADMTPRAMLDSGADLIVFA 55 Query: 137 MATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLG 196 ATYGEG+ F++ L+ET DL+G++FAVFGLG+ Y FN G L LG Sbjct: 56 TATYGEGEFAGGGAAFFETLRETKPDLSGLRFAVFGLGDSYYTTFNQAGATAATILASLG 115 Query: 197 AQRIFELGLGDDDGNLEED--FITWREQFWPAVCE 229 ++ + D + W + A+ Sbjct: 116 GTQVGDTARHDTSSGDDPAATAAEWAREILTALAT 150 >3KAQ-A nrPDB Length = 147 Score = 116 bits (289), Expect = 4e-26, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 60/151 (39%), Gaps = 7/151 (4%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 +++ +GS TG E A +L + G + E +L+ V+ + Sbjct: 2 KVLILFGSSTGNTESIAQKLEELVAAGGHEVTLLNAAEASADNLAD----GYDAVLMGCS 57 Query: 139 TYGEGDPTDNAQDFYDWLQET-DVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGA 197 +G D + DF E ++ L G K A F G+ YEH+ ++++ LGA Sbjct: 58 AWGMEDL-ELQDDFAPLFDEMENMGLKGKKLAAFASGDMEYEHYCGAVPAIEEKARGLGA 116 Query: 198 QRIFE-LGLGDDDGNLEEDFITWREQFWPAV 227 + I E L + D + + + E + Sbjct: 117 EVICEGLKIEGDASSDPDAVSAFAEDVLKKL 147 >6FSI-A nrPDB Length = 147 Score = 115 bits (287), Expect = 8e-26, Method: Composition-based stats. Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 6/136 (4%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 +++ + S +G EE A+ ++ D D + S L + D ++ Sbjct: 2 KLVMIFASMSGNTEEMADHIAGVIRETENEIEVIDI--MDSPEASILEQYDG--IILGAY 57 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQ 198 T+G+GD D+ DFYD + +DLTG K AVFG + Y + + ++L++ GA Sbjct: 58 TWGDGDLPDDFLDFYDAMDS--IDLTGKKAAVFGSCDSAYPKYGVAVDILIEKLQERGAA 115 Query: 199 RIFELGLGDDDGNLEE 214 + E + E+ Sbjct: 116 VVLEGLKVELTPEDED 131 >5B3K-A nrPDB Length = 150 Score = 93.3 bits (230), Expect = 3e-19, Method: Composition-based stats. Identities = 37/153 (24%), Positives = 59/153 (38%), Gaps = 8/153 (5%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 + + GS GTAEE A K G+ + A L L + + Sbjct: 2 KVAILSGSVYGTAEEVARHAQKLLSAAGL-----EASHLPRASLDELKAFAPEAFLVVTS 56 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTY-EHFNAMGKYVDQRLEQLGA 197 T G G+ DN Q Y +++ G+ V GLG+ +Y + F G+ V + +LG Sbjct: 57 TTGMGELPDNLQPLYYAIRDQLPAWHGLPGGVIGLGDSSYGDTFAGGGEQVRELFGELGV 116 Query: 198 QRIFELGLGDDDG--NLEEDFITWREQFWPAVC 228 + + + D E D W +F A+ Sbjct: 117 REVLPMLRLDASETVTPETDAEPWLAEFAAALK 149 >1AG9-A nrPDB Length = 175 Score = 78.3 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 35/175 (20%), Positives = 66/175 (37%), Gaps = 31/175 (17%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYG 141 +F+GS TG E A + K + + +D+A S +++ + T+ Sbjct: 5 IFFGSDTGNTENIAKMIQKQLGKDV-------ADVHDIAKSSKEDLEAYDILLLGIPTWY 57 Query: 142 EGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKT-Y-EHFNAMGKYVDQRLEQLGAQR 199 G+ + DF+ L+E +D G A+FG G++ Y E+F + +E GA Sbjct: 58 YGEAQCDWDDFFPTLEE--IDFNGKLVALFGCGDQEDYAEYFCDALGTIRDIIEPRGATI 115 Query: 200 IFE--------------------LGLGDDDGNLEEDFITWREQFWPAVCEFFGVE 234 + +GL D+ E E++ + E ++ Sbjct: 116 VGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKWVKQISEELHLD 170 >2V5U-A nrPDB Length = 169 Score = 72.5 bits (176), Expect = 6e-13, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 11/127 (8%) Query: 77 GRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFC 136 + I +FYG+QTG E A + + D + ++ DL+ ++ Sbjct: 1 AKKIGLFYGTQTGKTESVAEIIRDEF--GNDVVTLHDVSQAEVTDLNDYQY-----LIIG 53 Query: 137 MATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKT-Y-EHFNAMGKYVDQRLEQ 194 T+ G+ + + Y L DVD G A FG G++ Y ++F +++++ Q Sbjct: 54 CPTWNIGELQSDWEGLYSELD--DVDFNGKLVAYFGTGDQAGYADNFQDAIGILEEKISQ 111 Query: 195 LGAQRIF 201 G + + Sbjct: 112 RGGKTVG 118 >1CZN-A nrPDB Length = 169 Score = 69.1 bits (167), Expect = 7e-12, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 69/177 (38%), Gaps = 29/177 (16%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 I +FYG+QTG + A + ++ + D D +DL++ ++ Sbjct: 1 AKIGLFYGTQTGVTQTIAESIQQEFGGESI-VDLNDIANADASDLNAY-----DYLIIGC 54 Query: 138 ATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK--TYEHFNAMGKYVDQRLEQL 195 T+ G+ + + YD L V+ G K A FG G++ ++F +++++ L Sbjct: 55 PTWNVGELQSDWEGIYDDLDS--VNFQGKKVAYFGAGDQVGYSDNFQDAMGILEEKISSL 112 Query: 196 GAQRIFE-------------------LGLGDDDGNLEEDFITWREQFWPAVCEFFGV 233 G+Q + +GL D+ N + + + + FG+ Sbjct: 113 GSQTVGYWPIEGYDFNESKAVRNNQFVGLAIDEDNQPDLTKNRIKTWVSQLKSEFGL 169 >2FCR-A nrPDB Length = 173 Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 13/178 (7%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 I +F+ + TG E A+ + K + D D+ D +L D L+ Sbjct: 1 KIGIFFSTSTGNTTEVADFIGKTLGAKADAPIDVD----DVTDPQALK--DYDLLFLGAP 54 Query: 139 TYGEGDPTD-NAQDFYDWLQETDV--DLTGVKFAVFGLGNKT-YE-HFNAMGKYVDQRLE 193 T+ G T+ + + ++L + D+ + A+FGLG+ Y +F + + Sbjct: 55 TWNTGADTERSGTSWDEFLYDKLPEVDMKDLPVAIFGLGDAEGYPDNFCDAIEEIHDCFA 114 Query: 194 QLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHE 251 + GA+ + DD + EE +F + + E+ E VV E Sbjct: 115 KQGAKPVG--FSNPDDYDYEESKSVRDGKFLGLPLDMVNDQIPMEKRVAGWVEAVVSE 170 >1FLA-A nrPDB Length = 138 Score = 62.9 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 64/146 (43%), Gaps = 17/146 (11%) Query: 82 VFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYG 141 + Y S TG E+ A ++K G D +++D++ +++ +++ + Sbjct: 3 IVYWSGTGNTEKMAELIAKGIIESG-----KDVNTINVSDVNIDELLNEDILILGCSAMD 57 Query: 142 EGDPTDNAQDFYDWLQETDVDLTGVKFAVFGL---GNKTYEHFNAMGKYVDQRLEQLGAQ 198 + ++ +F +++E ++G K A+FG G+ + + ++R+ G Sbjct: 58 DEVLEES--EFEPFIEEISTKISGKKVALFGSYGWGDGKW------MRDFEERMNGYGCV 109 Query: 199 RI-FELGLGDDDGNLEEDFITWREQF 223 + L + ++ E+D I + ++ Sbjct: 110 VVETPLIVQNEPDEAEQDCIEFGKKI 135 >2WC1-A nrPDB Length = 182 Score = 61.0 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 14/132 (10%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 I +F+GS TGT + A ++ KD + + D+AD + ++ Sbjct: 2 AKIGLFFGSDTGTTRKIAKQI-KDMFDDEVMAKPLNVNRADVADF-----MAYDFLILGT 55 Query: 138 ATYGEGDPTDNAQD-----FYDWLQE-TDVDLTGVKFAVFGLGNK-TYE-HFNAMGKYVD 189 T G+G + + + ++L D D +G A+FGLG++ TY F ++ Sbjct: 56 PTLGDGQLPGLSANAASESWEEFLPRIADQDFSGKTIALFGLGDQVTYPLEFVNALFFLH 115 Query: 190 QRLEQLGAQRIF 201 + GA + Sbjct: 116 EFFSDRGANVVG 127 >2BMV-A nrPDB Length = 164 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 65/173 (37%), Gaps = 34/173 (19%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 I +F+G+ +G AE A ++SK + E D+A S + V+ Sbjct: 3 KIGIFFGTDSGNAEAIAEKISKA---------IGNAEVVDVAKASKEQFNSFTKVILVAP 53 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK-TY-EHFNAMGKYVDQRLEQ-- 194 T G GD + +DF L+ + D + GLG++ TY E F ++ ++ + Sbjct: 54 TAGAGDLQTDWEDFLGTLEAS--DFANKTIGLVGLGDQDTYSETFAEGIFHIYEKAKAGK 111 Query: 195 ------------------LGAQRIFELGLGDDDGNL-EEDFITWREQFWPAVC 228 G + + + D+ +L +E W EQ + Sbjct: 112 VVGQTSTDGYHFEASKAVEGGKFVGLVIDEDNQDDLTDERISKWVEQVKGSFA 164 >2FZ5-A nrPDB Length = 137 Score = 59.8 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 46/138 (33%), Gaps = 16/138 (11%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 + + Y S TG E AN + G AD E D + K +++ Sbjct: 2 VEIVYWSGTGNTEAMANEIEAAVKAAG-----ADVESVRFEDTNVDDVASKDVILLGCPA 56 Query: 140 YGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGL---GNKTYEHFNAMGKYVDQRLEQLG 196 G + D+ + + + L G K +FG G+ + QR E G Sbjct: 57 MGSEELEDSVVE--PFFTDLAPKLKGKKVGLFGSYGWGSGEW------MDAWKQRTEDTG 108 Query: 197 AQRIFELGLGDDDGNLEE 214 A I + + N E Sbjct: 109 ATVIGTAIVNEMPDNAPE 126 >1YOB-A nrPDB Length = 179 Score = 59.0 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 34/180 (18%), Positives = 64/180 (35%), Gaps = 37/180 (20%) Query: 78 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCM 137 I +F+GS TG + A + K M + ++ +S+ ++ Sbjct: 1 AKIGLFFGSNTGKTRKVAKSIKKRFDDETMS------DALNVNRVSAEDFAQYQFLILGT 54 Query: 138 ATYGEGDPTDNAQD-----FYDWLQETDV-DLTGVKFAVFGLGNK-TY-EHFNAMGKYVD 189 T GEG+ + D + ++L + + D +G A+FGLG++ Y E++ + Sbjct: 55 PTLGEGELPGLSSDAENESWEEFLPKIEGLDFSGKTVALFGLGDQVGYPENYLDALGELY 114 Query: 190 QRLEQLGAQRIFE-----------------------LGLGDDDGNLEEDFITWREQFWPA 226 + GA+ + L L + G +E W Q P Sbjct: 115 SFFKDRGAKIVGSWSTDGYEFESSEAVVDGKFVGLALDLDNQSGKTDERVAAWLAQIAPE 174 >2MTB-A nrPDB Length = 173 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 67/180 (37%), Gaps = 36/180 (20%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 N+ +FYGS T E A ++ ++L D S +++ + Sbjct: 2 NMGLFYGSSTCYTEMAAEKIRDIIGPEL-------VTLHNLKDDSPKLMEQYDVLILGIP 54 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNK-TY-EHFNAMGKYVDQRLEQLG 196 T+ G+ ++ + +D L + + L G A++GLG++ Y E F + +L G Sbjct: 55 TWDFGEIQEDWEAVWDQLDDLN--LEGKIVALYGLGDQLGYGEWFLDALGMLHDKLSTKG 112 Query: 197 AQRIFE---------------------LGLGDDDGNL----EEDFITWREQFWPAVCEFF 231 + + +GL D+ N +E +W EQ + E + Sbjct: 113 VKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSWCEQILNEMAEHY 172 >1KRH-A nrPDB Length = 338 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 47/203 (23%), Positives = 76/203 (37%), Gaps = 37/203 (18%) Query: 438 RPPIDHLCEL-----LPRLQ-ARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVAT 491 +P I L LP R YS +S + V G++ + Sbjct: 134 QPDIHFLAGQYVNVTLPGTTETRSYSFSSQPGN-----RLTGFVVR-NVPQGKM-----S 182 Query: 492 SWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLR 551 +L + AG + P F L PV+M+ GTGIAPF+ +Q L Sbjct: 183 EYLSVQAKAG-DKMSFTGPF----GSFYL-RDVKRPVLMLAGGTGIAPFLSMLQ---VLE 233 Query: 552 EQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGAL--TQLNVAFSREQ-AHKVYVQHL 608 ++G E L +G + D D + E+L + + VA + Q K YV Sbjct: 234 QKGSEH-PVRLVFGVTQ-DCDLVALEQLDALQQKLPWFEYRTVVAHAESQHERKGYVTGH 291 Query: 609 LKRDREHLWKLIHEGGAHIYVCG 631 ++ + ++ G +Y+CG Sbjct: 292 IE------YDWLNGGEVDVYLCG 308 >5OGX-A nrPDB Length = 336 Score = 48.6 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 24/151 (15%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATS-WLRAKEPAGENGGRALVPMF 512 R YS+A+++ +E + RV GVAT WL AG + A P+ Sbjct: 147 RQYSLANTADEDK--------VLELHVR--RVPGGVATDGWLFDGLAAG-DRVEATGPL- 194 Query: 513 VRKSQFRLP---FKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRS 569 F LP P++++G GTG+AP +G I A R +EV LLY+G R + Sbjct: 195 ---GDFHLPPPDEDDGGPMVLIGGGTGLAPLVG-IARTALARHPSREV---LLYHGVRGA 247 Query: 570 DEDYLYREELARFHKDGALTQLNVAFSREQA 600 D A ++ + S E Sbjct: 248 -ADLYDLGRFAEIAEEHPGFRFVPVLSDEPD 277 >3OZU-A nrPDB Length = 403 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 34/200 (17%), Positives = 62/200 (31%), Gaps = 26/200 (13%) Query: 452 QARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPM 511 Q R YS++ + + G G ++ L G + + P Sbjct: 204 QIRQYSLSDMPNGRSYRISV------KREGGGPQPPGYVSNLLHDHVNVG-DQVKLAAP- 255 Query: 512 FVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDE 571 F + + TP++++ G G+ P + ++ + + +G R S Sbjct: 256 ---YGSFHIDVDAKTPIVLISGGVGLTPMVSMLKVAL-----QAPPRQVVFVHGARNSAV 307 Query: 572 DYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRD-----REHLWKLIHEGGAH 626 + R+ L K L V + +Q VQ + + K I A Sbjct: 308 -HAMRDRLREAAKTYENLDLFVFY--DQPLPEDVQGRDYDYPGLVDVKQIEKSILLPDAD 364 Query: 627 IYVCGDAR--NMAKDVQNTF 644 Y+CG M D Sbjct: 365 YYICGPIPFMRMQHDALKNL 384 >4EH1-A nrPDB Length = 243 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 65/191 (34%), Gaps = 24/191 (12%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFV 513 R YS++ +S + + V G N G+ + +L G V ++ Sbjct: 55 RQYSLSHASNGREYRISVKREGV------GSDNPGLVSHYLHNNVKVG-----DSVKLYA 103 Query: 514 RKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDY 573 F + PV+++ G G P + A + G Y C + E Sbjct: 104 PAGDFFYVERER-PVVLISAGVGATPMQAILHTLAKQNKSGVTY-----LYACNSAKEHT 157 Query: 574 LYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDA 633 +E + G + Q+ + R+++ +Q + L I +G Y+CG Sbjct: 158 FAQETAQLIAQQGWMQQV---WYRDESADDVLQGEM--QLAELILPIEDGD--FYLCGPI 210 Query: 634 RNMAKDVQNTF 644 M V+ Sbjct: 211 GFMQYVVKQLL 221 >2X2P-A nrPDB Length = 119 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 26/115 (22%) Query: 80 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMAT 139 ++V Y S TG + F H+ M + D + ID+ ++ T Sbjct: 1 MLVAYDSMTGNVKRF-------IHKLNMPAVQIDEDLV----------IDEDFILI-TYT 42 Query: 140 YGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTY-EHFNAMGKYVDQRLE 193 G G+ + DF L+ + L G V GN+ + + F A + + E Sbjct: 43 TGFGNVPERVLDF---LERNNEKLKG----VSASGNRNWGDMFGASADKISTKYE 90 >5WID-A nrPDB Length = 149 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 19/127 (14%), Positives = 41/127 (32%), Gaps = 15/127 (11%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 IV Y S +G + A + G+ + D + D+ + + + Sbjct: 2 KAIVVYLSTSGNTKAMAEAIGN-----GIESKNVDVQVISFYDVKLDELKEAEAIAVGSS 56 Query: 139 TYGEGDPTDNAQDFYDWLQETDVDLT--GVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLG 196 T+ ++ ET V G A FG +Y + +++ ++G Sbjct: 57 TF----YYKMLLPMEKFMDETLVASNPQGKIGAAFG----SYGWSGEAPILIAEKMREMG 108 Query: 197 AQRIFEL 203 + + Sbjct: 109 MTVMDPV 115 >3W2G-A nrPDB Length = 271 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 49/254 (19%), Positives = 87/254 (34%), Gaps = 33/254 (12%) Query: 395 EPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPR---- 450 P + L + + + + HIL + P+ L R Sbjct: 8 NPDIKYPLRLIDKEVVNHDTRRFRFALPSPEHILGL---------PVGQHIYLSARIDGN 58 Query: 451 LQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVP 510 L R Y+ SS V + + G + +L + + R Sbjct: 59 LVIRPYTPVSSDD-DKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMKIGDTIEFRGPNG 117 Query: 511 MFVRKSQFRL---PFKSTTPVI-------MVGPGTGIAPFMGFIQERAWLREQGKEVGET 560 + V + + + P K ++PVI M+ GTGI P + I RA +++ Sbjct: 118 LLVYQGKGKFAIRPDKKSSPVIKTVKSVGMIAGGTGITPMLQVI--RAIMKDPDDHTVCH 175 Query: 561 LLYYGCRRSDEDYLYREELARFHKDGALT-QLNVAFSREQAHKVYVQHLLKRD--REHLW 617 LL+ ++++D L R EL + + +L R Y Q + + R+HL Sbjct: 176 LLF--ANQTEKDILLRPELEELRNEHSARFKLWYTVDRAPEAWDYSQGFVNEEMIRDHLP 233 Query: 618 KLIHEGGAHIYVCG 631 E + +CG Sbjct: 234 PPEEEP--LVLMCG 245 >2R6H-A nrPDB Length = 290 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 61/157 (38%), Gaps = 20/157 (12%) Query: 452 QARYYSIASSSKVHPNSVHICAVAVE-------YEAKSGRVNKGVATSWLRAKEPAGENG 504 R YS+A+ N + + + K+G + G+++S++ + +P + Sbjct: 85 TVRAYSMANYPA-EGNIITLNVRIATPPFDRAANKWKAG-IKPGISSSYIFSLKPG--DK 140 Query: 505 GRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYY 564 P F + + ++ +G G G+AP I + G++V +Y Sbjct: 141 VMMSGP----YGDFHI-QDTDAEMLYIGGGAGMAPLRAQILHLFRTLKTGRKVS---YWY 192 Query: 565 GCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAH 601 G R S + Y E+ ++ + ++A S Q Sbjct: 193 GAR-SKNEIFYEEDFREIEREFPNFKFHIALSDPQPE 228 >6H0D-A nrPDB Length = 403 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 18/132 (13%), Positives = 38/132 (28%), Gaps = 10/132 (7%) Query: 66 ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSL 125 ++ + + N+ + Y S G A +++ + G+ + + E + ++ Sbjct: 244 YQQWLSEQQAQALNVALIYASAYGNTSTLAQAIARGITKAGVAVTAINAETSNAEEIKEA 303 Query: 126 PEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFG-LGNKTYEHFNAM 184 +F T G PT L F FG G Sbjct: 304 IGKSAGF-IFGSPTLGGHAPTPIQTALGITLANASKTQLCGVFGSFGWSGE--------A 354 Query: 185 GKYVDQRLEQLG 196 ++ + G Sbjct: 355 IDMLENKFRDAG 366 >1UMK-A nrPDB Length = 275 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 66/184 (35%), Gaps = 19/184 (10%) Query: 461 SSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRL 520 SS V + + G + +L + + R + V + + + Sbjct: 72 SSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKF 131 Query: 521 ---PFKSTTPVI-------MVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSD 570 P K + P+I M+ GTGI P + I RA +++ LL+ +++ Sbjct: 132 AIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVI--RAIMKDPDDHTVCHLLF--ANQTE 187 Query: 571 EDYLYREELARFHKDGALT-QLNVAFSREQAHKVYVQHLLKRD--REHLWKLIHEGGAHI 627 +D L R EL + +L R Y Q + + R+HL E + Sbjct: 188 KDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEP--LV 245 Query: 628 YVCG 631 +CG Sbjct: 246 LMCG 249 >5THX-A nrPDB Length = 266 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 33/173 (19%), Positives = 69/173 (39%), Gaps = 40/173 (23%) Query: 441 IDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRV-NKGVATSWLRAKEP 499 + + + P + R YS+AS++ + ++ V+ + R+ + V L +K+P Sbjct: 48 VGLMADGKPLM--RAYSVASAN--WEEHLEFFSIKVQDGPLTSRLQHLKVGDEVLISKKP 103 Query: 500 AGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGE 559 G L + ++ GTGIAPF+ ++ E ++ + Sbjct: 104 TGTLVACDL--------------NPGKHLYLLSTGTGIAPFLSITKD----PEIYEQFEK 145 Query: 560 TLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRD 612 +L +G R Y+++LA + + F++E Y+ L+K Sbjct: 146 IILVHGVR-------YKKDLAYYDR----------FTKELPEHEYLGDLVKEK 181 >6O0A-A nrPDB Length = 413 Score = 38.2 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 49/118 (41%), Gaps = 12/118 (10%) Query: 520 LPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREEL 579 L +P++++ G G+ P + F+++ A + + + ++ RS + R EL Sbjct: 273 LETDPNSPLVLICAGIGVTPVLAFVEKLAAQKSERE-----VMIIASSRSLAEAPLRGEL 327 Query: 580 ARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMA 637 K+ ++ ++E+ +V R + L A +++CG + M Sbjct: 328 LERAKELKKAKVLYGTTQEKDGD-FV------GRIDVSTLDIPANASVFLCGPLKFMQ 378 >4N82-B nrPDB Length = 178 Score = 37.5 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 43/126 (34%), Gaps = 18/126 (14%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADL----SSLPEIDKSLVV 134 + + Y S +G E F RL+ S + E+ + DL E+D + Sbjct: 23 KVSLVYISLSGNTESFVRRLTDYLLEQH---PSLEVEKIHIKDLVKERQPFFEMDNPFIA 79 Query: 135 FCMATY-------GEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEH-FNAMGK 186 F + TY GD D D++ V G GN+ + + + K Sbjct: 80 F-LPTYLEGGNGVDNGDVEILTTDVGDFI--AYGQNASKCLGVIGSGNRNFNNQYCLTAK 136 Query: 187 YVDQRL 192 +R Sbjct: 137 QYSERF 142 >4B4D-A nrPDB Length = 262 Score = 36.7 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 34/141 (24%), Positives = 56/141 (39%), Gaps = 22/141 (15%) Query: 441 IDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPA 500 I E P L R YSIAS++ H+ + G + TS L+ +P Sbjct: 44 IGLETETRPLL--RAYSIASANWEE----HL--EFFSIKVPDGPL-----TSRLQHIQP- 89 Query: 501 GENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGET 560 G + LV + + ++G GTG+AP++ I++ E + + Sbjct: 90 ---GDKVLVGKKPTGTLLISDLHPGRNLYLLGTGTGLAPWLSIIKD----PETYERFDKV 142 Query: 561 LLYYGCRRSDEDYLYREELAR 581 +L G R +D YR+ R Sbjct: 143 ILTQGVR-FVQDLAYRDYFER 162 >1A8P-A nrPDB Length = 258 Score = 36.3 bits (82), Expect = 0.049, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 50/119 (42%), Gaps = 21/119 (17%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRV-NKGVATSWLRAKEPAGENGGRALVPMF 512 R YSIAS + + + ++ V+ + R+ + + +++P G L+P Sbjct: 51 RAYSIASPN--YEEHLEFFSIKVQNGPLTSRLQHLKEGDELMVSRKPTGTLVTSDLLP-- 106 Query: 513 VRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDE 571 M+ GTG+APFM IQ+ E + + +L +G R+ +E Sbjct: 107 --GKHLY----------MLSTGTGLAPFMSLIQD----PEVYERFEKVVLIHGVRQVNE 149 >2VNH-A nrPDB Length = 272 Score = 35.9 bits (81), Expect = 0.051, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 30/140 (21%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRV-----NKGVATSWLRAKEPAGENGGRAL 508 R YSIAS + + + G + + V + +P G AL Sbjct: 64 RAYSIASPAWDEELEFY------SIKVPDGPLTSRLQHIKVGEQIILRPKPVGTLVIDAL 117 Query: 509 VPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRR 568 +P RL F + GTGIAPF ++E E ++ E ++ + CR Sbjct: 118 LP------GKRLWF--------LATGTGIAPFASLMRE----PEAYEKFDEVIMMHACR- 158 Query: 569 SDEDYLYREELARFHKDGAL 588 + + Y +L ++ L Sbjct: 159 TVAELEYGRQLVEALQEDPL 178 >4DIK-A nrPDB Length = 410 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 32/96 (33%), Gaps = 2/96 (2%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPE--IDKSLVVFC 136 + V Y S G E + G + + + +S + + D ++F Sbjct: 267 KVTVIYDSMYGFVENVMKKAIDSLKEKGFTPVVYKFSDEERPAISEILKDIPDSEALIFG 326 Query: 137 MATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFG 172 ++TY + + + + + + F V G Sbjct: 327 VSTYEAEIHPLMRFTLLEIIDKANYEKPVLVFGVHG 362 >1TLB-A nrPDB Length = 326 Score = 34.0 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 40/209 (19%), Positives = 66/209 (31%), Gaps = 49/209 (23%) Query: 500 AGENGGRALVPMFVRKSQFRLPFKSTT--PV------------IMVGPGTGIAPFMGFIQ 545 G+ A+ M RLP T PV +++ P AP + Sbjct: 73 YGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHPVNPHAP-TTHLN 131 Query: 546 ERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHK------DGALTQLNVAFSREQ 599 R + +T + G YLY E+ FH+ D T L F + Sbjct: 132 YRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWC 191 Query: 600 AHKVYVQHLL--------------KRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFY 645 Y+ H +RD + + K++ + C DA ++ Sbjct: 192 DEYFYITHRKETRGIGGIFFDDYDERDPQEILKMVED-------CFDA------FLPSYL 238 Query: 646 DIVAEFGPMEHTQAVDYVKKLMTKGRYSL 674 IV M +T+ + + +GRY Sbjct: 239 TIVKRRKDMPYTKEEQQWQAIR-RGRYVE 266 >4U9U-A nrPDB Length = 281 Score = 33.6 bits (75), Expect = 0.26, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 30/79 (37%), Gaps = 4/79 (5%) Query: 523 KSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARF 582 + ++ +G G G+AP I ++ + + + +YG R E + Y E+ Sbjct: 144 DTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKR---KMSYWYGARSKREMF-YVEDFDGL 199 Query: 583 HKDGALTQLNVAFSREQAH 601 + + A S Q Sbjct: 200 AAENDNFVWHCALSDPQPE 218 >4P6V-F nrPDB Length = 408 Score = 33.6 bits (75), Expect = 0.26, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 30/79 (37%), Gaps = 4/79 (5%) Query: 523 KSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARF 582 + ++ +G G G+AP I ++ + + + +YG R E + Y E+ Sbjct: 271 DTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKR---KMSYWYGARSKREMF-YVEDFDGL 326 Query: 583 HKDGALTQLNVAFSREQAH 601 + + A S Q Sbjct: 327 AAENDNFVWHCALSDPQPE 345 >6G70-A nrPDB Length = 670 Score = 33.6 bits (75), Expect = 0.31, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 28/84 (33%), Gaps = 3/84 (3%) Query: 87 QTGTAEEFA--NRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGD 144 TG + E A + M P+ A S+ + V + T EGD Sbjct: 21 STGNSSEVAVVEHPDFSTEIMNVTEMEQSPDASPSAHASTEENEMANAVNLPV-TEAEGD 79 Query: 145 PTDNAQDFYDWLQETDVDLTGVKF 168 + F+ ++ D TG + Sbjct: 80 FPPEFEKFWKTVEMNPQDFTGWVY 103 >4G1B-A nrPDB Length = 399 Score = 33.2 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 38/94 (40%), Gaps = 6/94 (6%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFV 513 R+YS+ S+S + + A + G+ + +L G + + P Sbjct: 207 RHYSLCSASTKNGLRFAVKMEAARENFPA-----GLVSEYLHKDAKVG-DEIKLSAPAGD 260 Query: 514 RKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQER 547 L ++ P++++ G G+ P + ++E+ Sbjct: 261 FAINKELIHQNEVPLVLLSSGVGVTPLLAMLEEQ 294 >1IQV-A nrPDB Length = 218 Score = 33.2 bits (74), Expect = 0.34, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 34/95 (35%), Gaps = 4/95 (4%) Query: 402 LHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASS 461 + ++A E + V R + PSL+P L PRL + + Sbjct: 1 MKEVAKPLQERFFIPHEIKVMGRWSTEDVEVKDPSLKP----YINLEPRLLPHTHGRHAK 56 Query: 462 SKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRA 496 +VHI + +SG + VA ++R Sbjct: 57 KHFGKANVHIVERLINKVMRSGGSHYKVAGHFMRR 91 >1GVH-A nrPDB Length = 396 Score = 33.2 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 30/197 (15%), Positives = 58/197 (29%), Gaps = 28/197 (14%) Query: 446 ELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGG 505 E P + R YS+ Y R G ++WL G Sbjct: 196 EGFPHQEIRQYSLTRKPDGK-----------GYRIAVKREEGGQVSNWLHNHANVG---- 240 Query: 506 RALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYG 565 +V + F + TPV ++ G G P + + L + G ++ Sbjct: 241 -DVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLAMLDT---LAKAGHTAQVNW-FHA 295 Query: 566 CRRSDEDYLYREELARFHKDGALTQLNV-AFSREQAHKVYVQHLLKRDR----EHLWKLI 620 D + + +E+ + +L + + R+ + + + L Sbjct: 296 AENGDV-HAFADEVKELGQ--SLPRFTAHTWYRQPSEADRAKGQFDSEGLMDLSKLEGAF 352 Query: 621 HEGGAHIYVCGDARNMA 637 + Y+CG M Sbjct: 353 SDPTMQFYLCGPVGFMQ 369 >2ARK-A nrPDB Length = 188 Score = 32.9 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 79 NIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMA 138 ++V Y ++TG ++ A +++ A + G + D A + D + + Sbjct: 6 KVLVIYDTRTGNTKKMAELVAEGARS--LEGTEVRLKHVDEATKEDVLWADG---LAVGS 60 Query: 139 TYGEGDPTDNAQDFYDW-LQETDVDLTGVKFAVF 171 G + + F+D L + ++ G F Sbjct: 61 PTNMGLVSWKMKRFFDDVLGDLWGEIDGKIACAF 94 >2QDX-A nrPDB Length = 257 Score = 32.9 bits (73), Expect = 0.44, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 44/123 (35%), Gaps = 29/123 (23%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRV-----NKGVATSWLRAKEPAGENGGRAL 508 R YSIAS + H+ + G + + + +++P G L Sbjct: 50 RAYSIASPNYEE----HL--EFFSIKVPDGPLTSRLQHLKEGDELMVSRKPTGTLVHDDL 103 Query: 509 VPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRR 568 +P L + GTG+APF+ IQ+ E + + +L +G R Sbjct: 104 LP----GKHLYL----------LSTGTGMAPFLSVIQD----PETYERYEKVILVHGVRW 145 Query: 569 SDE 571 E Sbjct: 146 VSE 148 >1TK1-A nrPDB Length = 260 Score = 32.1 bits (71), Expect = 0.80, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 40/129 (31%), Gaps = 21/129 (16%) Query: 500 AGENGGRALVPMFVRKSQFRLPFKSTT--PV------------IMVGPGTGIAPFMGFIQ 545 G+ A+ M RLP T PV +++ P AP + Sbjct: 70 YGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHPVNPHAP-TTHLN 128 Query: 546 ERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHK------DGALTQLNVAFSREQ 599 R + +T + G YLY E+ FH+ D T L F + Sbjct: 129 YRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWC 188 Query: 600 AHKVYVQHL 608 Y+ H Sbjct: 189 DEYFYITHR 197 >3GZX-A nrPDB Length = 457 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 53/136 (38%), Gaps = 6/136 (4%) Query: 295 GTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEE 354 E L ++L + ++ R G H A + NDS++ + ++G + + E+ Sbjct: 248 PPEMDLTQIQLSKNGNQFRSAWGGHGAGWFINDSSI---LLSVVGPKITQYWTQGPAAEK 304 Query: 355 SNKKHPFPCPTT-YRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGK 413 + ++ P + +T + + P N + + P+E E + + + Sbjct: 305 AARRVPQLPILDMFGQHMTVFPTCSFLPGINTIRTW--HPRGPNEVEVWAFVLVDADAPE 362 Query: 414 ELYLSWVVEARRHILA 429 ++ + ++ R A Sbjct: 363 DIKEEFRLQNIRTFNA 378 >3J0A-A nrPDB Length = 844 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 28/118 (23%) Query: 268 SYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPAND 327 +Y N PP + +TA R L+ + R + D+ PAN Sbjct: 490 NYLNSLPPGVFSH-----LTALRGLSLNSNRLTVLSHNDL----------------PANL 528 Query: 328 SALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYY----LDITNPP 381 L ++L + DV +SL+ LD NK F C T + + + I PP Sbjct: 529 EILDISRNQLLAPNPDVFVSLSVLDITHNK---FICECELSTFINWLNHTNVTIAGPP 583 >1RLJ-A nrPDB Length = 139 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 17/120 (14%), Positives = 35/120 (29%), Gaps = 25/120 (20%) Query: 75 KTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVV 134 ++ + + + S+TG + F N+ R D V Sbjct: 6 QSNAMVQIIFDSKTGNVQRFVNKTGFQQIRKVDEMDHVDTP-----------------FV 48 Query: 135 FCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTY-EHFNAMGKYVDQRLE 193 T G + Q F + + V GNK + ++F + ++ + Sbjct: 49 LVTYTTNFGQVPASTQSFLEKY-------AHLLLGVAASGNKVWGDNFAKSADTISRQYQ 101 >4FK8-A nrPDB Length = 271 Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 46/115 (40%), Gaps = 21/115 (18%) Query: 454 RYYSIASSSKVHPNSVHICAVAVEYEAKSGRV-NKGVATSWLRAKEPAGENGGRALVPMF 512 R YSI S + + + ++ V+ + R+ + V L K+P G L+P Sbjct: 66 RAYSIVSPN--YEEHLEFFSIKVQNGPLTSRLQHLKVGDPVLIGKKPTGTLVADNLLP-- 121 Query: 513 VRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCR 567 + M+ GTG+APFM I++ + + +L + CR Sbjct: 122 ------------GKTLWMLSTGTGLAPFMSIIRDPDIY----ERFDKVVLTHTCR 160 >6C2V-A nrPDB Length = 115 Score = 31.3 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 45 RKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR 104 RK KEE+P+ ++I+T E+ ++ +I+V G A + K R Sbjct: 23 RKAKEEVPD-AEIRTVTTKEDAKRVAEEAERRNADIVVIVGPSGSGKSTLAKIVKKIIAR 81 Query: 105 YGMRGMSADPEE 116 G + + EE Sbjct: 82 AGAKTIEVTTEE 93 >4C5O-A nrPDB Length = 357 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 28/102 (27%), Gaps = 14/102 (13%) Query: 131 SLVVFCMATYGEGDPTD-------NAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNA 183 V+ T+GE + + T G++ A+ G GN + Sbjct: 122 RAVISATGTWGEAYTPEYQGLESFAGIQLHSAHYSTPAPFAGMRVAIIGGGNSGAQILAE 181 Query: 184 MGKYVDQRLEQLGAQRIFELGLGDDDGN---LEEDFITWREQ 222 + + R L DD E W+ Q Sbjct: 182 VSTVAETTWI----TRTEPAFLADDVDGRVLFERATERWKAQ 219 >1P35-A nrPDB Length = 299 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 59/181 (32%), Gaps = 21/181 (11%) Query: 228 CEFFGVEATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVT 287 C F VE ++ IR ++ + VY ++ + + F+ P + Sbjct: 1 CVIFPVEIDVSQTIIRDCQV---DKQTRELVYINKIMNTQLTKPVLMMFNISGPIRSVTR 57 Query: 288 ANR----KLNQGTERHLMHLELDISDS------KIRYESGDHVAVYPANDSALVNQIGEI 337 N ++ + LE D SD I+Y +H +V N S L ++ +I Sbjct: 58 KNNNLRDRIKSKVDEQFDQLERDYSDQMDGFHDSIKYFKDEHYSVSCQNGSVLKSKFAKI 117 Query: 338 LGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYY--LDITNPPRTNVLYELAQYASE 395 L +++ P YY + + P N ++ + Sbjct: 118 L--KSHDYTDKKSIEAYEKYCLPKL----VDERNDYYVAVCVLKPGFENGSNQVLSFEYN 171 Query: 396 P 396 P Sbjct: 172 P 172 >1CI3-M nrPDB Length = 249 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 38/105 (36%), Gaps = 21/105 (20%) Query: 474 VAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTT------- 526 Y + V + A +PA +A++P V K+ ++P+ + Sbjct: 5 AQQNYANPREATGRIVCANCHLAAKPAEIEVPQAVLPDSVFKAVVKIPYDHSVQQVQADG 64 Query: 527 --------PVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLY 563 V+M+ G IAP E E +EVG + L+ Sbjct: 65 SKGPLNVGAVLMLPEGFTIAP------EDRIPEEMKEEVGPSYLF 103 >3FPK-A nrPDB Length = 251 Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 46/124 (37%), Gaps = 14/124 (11%) Query: 530 MVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHK--DGA 587 M+ GT I P++ +Q Q + L+ R D Y + + +G Sbjct: 114 MLATGTAIGPYLSILQ-----YGQDVARFKNLVLVHAARFAADLSYLPLMLELQQRYEGK 168 Query: 588 LTQLNVAFSREQ-----AHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQN 642 L ++ SRE +V + + + + +H+ +CG+ + M +D Q Sbjct: 169 L-RIQTVVSRENVPGSLTGRVPALIENGELEKAVGLPMDKETSHVMLCGNPQ-MVRDTQQ 226 Query: 643 TFYD 646 + Sbjct: 227 LLKE 230 >2EIX-A nrPDB Length = 243 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 27/72 (37%), Gaps = 4/72 (5%) Query: 530 MVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALT 589 M+ GTGI P +Q + + KE L + D D L R EL K + Sbjct: 121 MIAGGTGITP---MLQVARAIIKNPKEKTIINLIFANVNED-DILLRTELDDMAKKYSNF 176 Query: 590 QLNVAFSREQAH 601 ++ + A Sbjct: 177 KVYYVLNNPPAG 188 >5MWL-A nrPDB Length = 471 Score = 30.2 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 52/145 (35%), Gaps = 16/145 (11%) Query: 503 NGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLL 562 +G +P R F + + P G PF + + K Sbjct: 112 SGYAMCLPNLTRLQTFHFAEHRPILCVEIKPKCGFIPFSNDVTH----EMKHKV------ 161 Query: 563 YYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHE 622 CR +L + ++ K L++ +Q ++ LL+ + +L I + Sbjct: 162 ---CRYCMHQHL-KVATGKWKKISKYCPLDLYSGNKQRMHFALRSLLQETQNNL--RIFK 215 Query: 623 GGAHIYVCGDARNMAKDVQNTFYDI 647 G IY CGDAR+ D++ + + Sbjct: 216 NGELIYGCGDARSPVADLKELAHHL 240 >3TC1-A nrPDB Length = 315 Score = 28.6 bits (62), Expect = 8.9, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 563 YYGCRRSDE--DYLYREELARFHKDG-----ALTQLNVAFSREQAHKVYVQHLLKRDREH 615 +G + D Y + K G AL+ + SR + V+V D++ Sbjct: 95 LFGNFNAVMLGDVFYSKAFFELSKMGELIAQALSNAVLRLSRGEIEDVFVGECFNSDKQK 154 Query: 616 LWKLIHEGGAHIYVCGDARNMA 637 W+++ + AH ++ ++MA Sbjct: 155 YWRILEDKTAH-FIEASLKSMA 175 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.123 0.309 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,592,045 Number of Sequences: 36641 Number of extensions: 923770 Number of successful extensions: 2771 Number of sequences better than 10.0: 80 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 2524 Number of HSP's gapped (non-prelim): 147 length of query: 678 length of database: 10,336,785 effective HSP length: 104 effective length of query: 574 effective length of database: 6,526,121 effective search space: 3745993454 effective search space used: 3745993454 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)