BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00375 (187 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3D84-X nrPDB 383 e-107 3GYF-A nrPDB 353 2e-98 1DR5-A nrPDB 303 2e-83 3VCO-A nrPDB 140 3e-34 5T0L-A nrPDB 125 1e-29 4ECK-A nrPDB 113 6e-26 3CD2-A nrPDB 109 8e-25 3K2H-A nrPDB 102 9e-23 3EEM-A nrPDB 100 7e-22 1IA3-A nrPDB 98 2e-21 1QZF-A nrPDB 97 6e-21 4DP3-A nrPDB 93 7e-20 1J3I-A nrPDB 92 2e-19 3RG9-A nrPDB 91 2e-19 2BL9-A nrPDB 89 1e-18 3IRM-A nrPDB 86 8e-18 1ZDR-A nrPDB 82 1e-16 3JW3-A nrPDB 77 4e-15 4KJL-A nrPDB 75 2e-14 4M7V-A nrPDB 72 1e-13 3IA5-A nrPDB 71 3e-13 3TQB-A nrPDB 69 2e-12 2JYB-A nrPDB 69 2e-12 4M2X-A nrPDB 64 3e-11 2W9S-A nrPDB 64 5e-11 3Q1H-A nrPDB 63 7e-11 2W3W-A nrPDB 63 8e-11 4OSG-A nrPDB 61 3e-10 3LG4-A nrPDB 58 2e-09 6CXM-A nrPDB 56 9e-09 6E4E-A nrPDB 55 2e-08 2L28-A nrPDB 51 3e-07 5ECC-A nrPDB 46 1e-05 3IX9-A nrPDB 44 4e-05 5DXV-A nrPDB 43 8e-05 1CZ3-A nrPDB 39 0.002 1TYG-A nrPDB 28 2.2 1Q8R-A nrPDB 27 3.8 3T8I-A nrPDB 27 5.2 3EVG-A nrPDB 27 5.5 >3D84-X nrPDB Length = 186 Score = 383 bits (984), Expect = e-107, Method: Compositional matrix adjust. Identities = 186/186 (100%), Positives = 186/186 (100%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 61 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI Sbjct: 1 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 60 Query: 62 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV 121 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV Sbjct: 61 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV 120 Query: 122 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 181 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE Sbjct: 121 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 180 Query: 182 VYEKKD 187 VYEKKD Sbjct: 181 VYEKKD 186 >3GYF-A nrPDB Length = 187 Score = 353 bits (907), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 168/187 (89%), Positives = 180/187 (96%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS 60 MV LNCIVAVSQNMGIGKNGDLPWPPLRNEF+YFQRMTTTSSVEGKQNLVIMG+KTWFS Sbjct: 1 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS 60 Query: 61 IPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSS 120 IPEKNRPLK RIN+VLSRELKEPP+GAHFL++SLDDAL+L EQPELA+KVDMVWIVGGSS Sbjct: 61 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS 120 Query: 121 VYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKF 180 VY+EAMN PGHL+LFVTRIMQ+FESDTFFPEIDL KYKLLPEYPGVLS+VQEEKGIKYKF Sbjct: 121 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF 180 Query: 181 EVYEKKD 187 EVYEK D Sbjct: 181 EVYEKND 187 >1DR5-A nrPDB Length = 189 Score = 303 bits (777), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 142/184 (77%), Positives = 164/184 (89%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 61 VR LN IVAV QNMGIGK+G+LPWPPLRNE+KYFQRMT+TS VEGKQN VIMG+KTWFSI Sbjct: 1 VRSLNSIVAVCQNMGIGKDGNLPWPPLRNEYKYFQRMTSTSHVEGKQNAVIMGKKTWFSI 60 Query: 62 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV 121 PEKNRPLKDRINIVLSRELKE P+GAH+L+KSLDDAL L++ PEL SKVDMVWIVGG++V Sbjct: 61 PEKNRPLKDRINIVLSRELKEAPKGAHYLSKSLDDALALLDSPELKSKVDMVWIVGGTAV 120 Query: 122 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 181 Y+ AM +P + RLFVTRI+ EFESDTFFPEID +KLL EYPGV +++QEE GI+YKFE Sbjct: 121 YKAAMEKPINHRLFVTRILHEFESDTFFPEIDYKDFKLLTEYPGVPADIQEEDGIQYKFE 180 Query: 182 VYEK 185 VY+K Sbjct: 181 VYQK 184 >3VCO-A nrPDB Length = 201 Score = 140 bits (354), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 76/181 (41%), Positives = 116/181 (64%), Gaps = 5/181 (2%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 LN +VAVS+N GIGK G LPW ++ + ++F+ +TT + G +N V+MGR TW SIPE Sbjct: 23 LNVVVAVSENWGIGKGGGLPWK-IKKDMEFFKTVTTKAH-PGLKNAVVMGRVTWESIPES 80 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PLKDRINIV+S L P + SL+ A+ L+ E +S VD V+I+GG +Y+E Sbjct: 81 FKPLKDRINIVVSSTLSHAPSFVQ-VVPSLNAAIDLLYNEEFSSIVDEVFIIGGYRLYKE 139 Query: 125 AMNQPGH-LRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVY 183 A+ Q + +R++ T I+ E + DT+FP++D K K + + P + ++ E G +KF VY Sbjct: 140 ALKQSIYPVRIYCTHILSEVDCDTYFPKVDWDKLKKV-DLPDIPADTFTENGFTFKFCVY 198 Query: 184 E 184 + Sbjct: 199 D 199 >5T0L-A nrPDB Length = 566 Score = 125 bits (313), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 77/208 (37%), Positives = 112/208 (53%), Gaps = 23/208 (11%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQ-NLVIMGRKTWF 59 M +P+ +VA++ GIG N LPWP L +FK+F R+T T+ E + N V+MGRKTW Sbjct: 1 MQKPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPEEASRFNAVVMGRKTWE 60 Query: 60 SIPEKNRPLKDRINIVLSRELKEPPRGAH----------FLAKSLDDALRLIEQPELASK 109 S+P K RPL DR+NIV+S LKE A + SL AL L+E+ E Sbjct: 61 SMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEE-EYKDS 119 Query: 110 VDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEI---DLGKYKLLPE---- 162 VD +++VGG+ +Y+ A++ L++TR+ +EF D FFP D+ K Sbjct: 120 VDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKSTAAEKDN 179 Query: 163 ----YPGVLSEVQEEKGIKYKFEVYEKK 186 P +S+ + G+ Y F V EK+ Sbjct: 180 EATYRPIFISKTFSDNGVPYDFVVLEKR 207 >4ECK-A nrPDB Length = 610 Score = 113 bits (282), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 68/186 (36%), Positives = 97/186 (52%), Gaps = 37/186 (19%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTS------------------ 42 M +P+ +VA++ GIG N LPWP L +FK+F R+T T+ Sbjct: 1 MQKPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPEEASRLNGWLPRKFAKT 60 Query: 43 --------SVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAH------ 88 SV + N V+MGRKTW S+P K RPL DR+NIV+S LKE A Sbjct: 61 GDSGLPSPSVGKRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEG 120 Query: 89 ----FLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFE 144 + SL AL L+E+ E VD +++VGG+ +Y+ A++ L++TR+ +EF Sbjct: 121 QQRVRVCASLPAALSLLEE-EYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFP 179 Query: 145 SDTFFP 150 D FFP Sbjct: 180 CDVFFP 185 >3CD2-A nrPDB Length = 206 Score = 109 bits (272), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 64/156 (41%), Positives = 97/156 (62%), Gaps = 11/156 (7%) Query: 3 RPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMT----TTSSVEGKQNLVIMGRKTW 58 + L IVA++ + GIG++ LPW L+ E YF+R+T T S E N+V+MGRKTW Sbjct: 5 KSLTLIVALTTSYGIGRSNSLPWK-LKKEISYFKRVTSFVPTFDSFES-MNVVLMGRKTW 62 Query: 59 FSIPEKNRPLKDRINIVLSR-ELKEPPRGAHFLAKSLDDALRLIEQ---PELASKVDMVW 114 SIP + RPLK RIN+V++R E + G H AKSLD AL L+ + E + +++ ++ Sbjct: 63 ESIPLQFRPLKGRINVVITRNESLDLGNGIH-SAKSLDHALELLYRTYGSESSVQINRIF 121 Query: 115 IVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFP 150 ++GG+ +Y+ AM+ P R+ T I ++ D FFP Sbjct: 122 VIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFP 157 >3K2H-A nrPDB Length = 511 Score = 102 bits (254), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 63/191 (32%), Positives = 109/191 (57%), Gaps = 21/191 (10%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTT------TSSVEGKQNLVIMGRKTW 58 L VAV+ N IG +PWP + ++F++ + TT S QN+VI GRKT+ Sbjct: 11 LTIFVAVALNKVIGHKNQIPWPHITHDFRFLRNGTTYIPPEVLSKNPDIQNVVIFGRKTY 70 Query: 59 FSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKV--DMVWIV 116 SIP+ + PLK+RIN++LSR +KE P + + L A+R +L + V + ++I+ Sbjct: 71 ESIPKASLPLKNRINVILSRTVKEVP--GCLVYEDLSTAIR-----DLRANVPHNKIFIL 123 Query: 117 GGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGI 176 GGS +Y+E ++ ++++TR+ +E+ DT+FP+I +++ P ++ + Sbjct: 124 GGSFLYKEVLDNGLCDKIYLTRLNKEYPGDTYFPDIP-DTFEITAISPTFSTDF-----V 177 Query: 177 KYKFEVYEKKD 187 Y F +YE+KD Sbjct: 178 SYDFVIYERKD 188 >3EEM-A nrPDB Length = 227 Score = 99.8 bits (247), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 63/155 (40%), Positives = 96/155 (61%), Gaps = 13/155 (8%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + + A+ MGIG G+LPW L E KYF+ +TT ++ KQN+VIMGRKTW SIP+K Sbjct: 7 VGIVAALLPEMGIGFQGNLPWR-LAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQK 65 Query: 65 NRPLKDRINIVLSR----ELKEPPRGAHFLAKSLDDALRLIEQPELA--SKVDMVWIVGG 118 RPL RIN+V+SR EL++ G + + SL + L + Q LA +K++ ++I+GG Sbjct: 66 FRPLPKRINVVVSRSFDGELRKVEDGIYH-SNSLRNCLTAL-QSSLANENKIERIYIIGG 123 Query: 119 SSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEID 153 +Y+++M+ H +T+IM E T P++D Sbjct: 124 GEIYRQSMDLADH--WLITKIMPLPE--TTIPQMD 154 >1IA3-A nrPDB Length = 192 Score = 98.2 bits (243), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 60/156 (38%), Positives = 90/156 (57%), Gaps = 14/156 (8%) Query: 1 MVRPLNCIV--AVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTW 58 M++P I+ A+ +GIG G +PW LR E +YF+ +TT ++ +N VIMGRKTW Sbjct: 1 MLKPNVAIIVAALKPALGIGYKGKMPWR-LRKEIRYFKDVTTRTTKPNTRNAVIMGRKTW 59 Query: 59 FSIPEKNRPLKDRINIVLSRELKEPPRGAHFL-AKSLDDALRLIEQPELASKVDMVWIVG 117 SIP+K RPL DR+NI+LSR + + + A S++ +L L+ S V+ V+I+G Sbjct: 60 ESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLV------SDVERVFIIG 113 Query: 118 GSSVYQEAMNQPGHLRLFVTRIM----QEFESDTFF 149 G+ +Y E +N L +T I + E DTF Sbjct: 114 GAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFL 149 >1QZF-A nrPDB Length = 521 Score = 96.7 bits (239), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 63/188 (33%), Positives = 108/188 (57%), Gaps = 15/188 (7%) Query: 3 RPLNCIVAVS-QNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 61 + ++ +VA S + GIG NG LPW + + K+F ++T K+N +IMGRKTW SI Sbjct: 4 KNVSIVVAASVLSSGIGINGQLPWS-ISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSI 62 Query: 62 PEKNRPLKDRINIVLSRELKEPPRGAHFLA-KSLDDALRLIEQPELASKVDMVWIVGGSS 120 RPLK+RI +V+S L + + + ++L+D+ IE ++ +++ GG S Sbjct: 63 GR--RPLKNRIIVVISSSLPQDEADPNVVVFRNLEDS---IENLMNDDSIENIFVCGGES 117 Query: 121 VYQEAMNQPGHLRLFVTRI-MQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYK 179 +Y++A+ R+++TR+ +++ E DT+FPEI LP Y +S+ K I Y Sbjct: 118 IYRDALKDNFVDRIYLTRVALEDIEFDTYFPEI---PETFLPVY---MSQTFCTKNISYD 171 Query: 180 FEVYEKKD 187 F ++EK++ Sbjct: 172 FMIFEKQE 179 >4DP3-A nrPDB Length = 608 Score = 92.8 bits (229), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 50/207 (24%) Query: 16 GIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGK---------------------------- 47 G+G G LPW + + KYF R TT E K Sbjct: 39 GLGNKGVLPWKCISLDMKYF-RAVTTYVNESKYEKLKYKRCKYLNKETVDNVNDMPNSKK 97 Query: 48 -QNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPE- 105 QN+V+MGR W SIP+K +PL +RIN++LSR LK+ + D+ + +I + E Sbjct: 98 LQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKK---------EDFDEDVYIINKVED 148 Query: 106 ---LASKVDM--VWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLL 160 L K++ +I+GGS VYQE + + +++ TRI +E D FFPEI+ +Y+++ Sbjct: 149 LIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQII 208 Query: 161 PEYPGVLSEVQEEKGIKYKFEVYEKKD 187 +S+V F +Y+K + Sbjct: 209 S-----VSDVYTSNNTTLDFIIYKKTN 230 >1J3I-A nrPDB Length = 280 Score = 91.7 bits (226), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 60/202 (29%), Positives = 98/202 (48%), Gaps = 40/202 (19%) Query: 16 GIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGK---------------------------- 47 G+G G LPW + KYF +TT + E K Sbjct: 39 GLGNKGVLPWKCNSLDMKYFCAVTTYVN-ESKYEKLKYKRCKYLNKETVDNVNDMPNSKK 97 Query: 48 -QNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAH-FLAKSLDDALRLIEQPE 105 QN+V+MGR +W SIP+K +PL +RIN++LSR LK+ ++ ++D + L+ + Sbjct: 98 LQNVVVMGRTSWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLN 157 Query: 106 LASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPG 165 +I+GGS VYQE + + +++ TRI +E D FFPEI+ +Y+++ Sbjct: 158 YYK----CFIIGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIIS---- 209 Query: 166 VLSEVQEEKGIKYKFEVYEKKD 187 +S+V F +Y+K + Sbjct: 210 -VSDVYTSNNTTLDFIIYKKTN 230 >3RG9-A nrPDB Length = 240 Score = 91.3 bits (225), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 51/149 (34%), Positives = 83/149 (55%), Gaps = 22/149 (14%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTT------TSSVEGKQNLVIMGR 55 +RP + +VA + GIG G +PW + + +YF+R+TT K+N V+MGR Sbjct: 26 LRPFSVVVASDEKGGIGDGGTIPWE-IPEDMQYFRRVTTNLRGKNVKPSPSKRNAVVMGR 84 Query: 56 KTWFSIPEKNRPLKDRINIVLSRE---------LKEPPRGAH------FLAKSLDDALRL 100 KTW S+P K RPL +R+N+VLSR + +P + A + L+DALR+ Sbjct: 85 KTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGIPDPIKRAEAANDVVAVNGGLEDALRM 144 Query: 101 IEQPELASKVDMVWIVGGSSVYQEAMNQP 129 + E S ++ V+ +GG ++Y++A+ P Sbjct: 145 LVSKEHTSSIETVFCIGGGTIYKQALCAP 173 >2BL9-A nrPDB Length = 238 Score = 89.0 bits (219), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 48/209 (22%) Query: 16 GIGKNGDLPWPPLRNEFKYFQRMTT----------------------------------- 40 G+G G LPW + KYF +TT Sbjct: 38 GLGNKGTLPWKCNSVDMKYFSSVTTYVDESKYEKLKWKRERYLRMEASQGGGDNTSGGDN 97 Query: 41 ---TSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSREL-KEPPRGAHFLAKSLDD 96 + + QN+V+MGR +W SIP++ +PL +RIN+VLS+ L KE + F+ S+DD Sbjct: 98 THGGDNADKLQNVVVMGRSSWESIPKQYKPLPNRINVVLSKTLTKEDVKEKVFIIDSIDD 157 Query: 97 ALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGK 156 L L+++ + +I+GG+ VY+E +++ +++ TRI + D FFPE D + Sbjct: 158 LLLLLKKLKYY----KCFIIGGAQVYRECLSRNLIKQIYFTRINGAYPCDVFFPEFDESE 213 Query: 157 YKLLPEYPGVLSEVQEEKGIKYKFEVYEK 185 +++ +SEV KG F VY K Sbjct: 214 FRVTS-----VSEVYNSKGTTLDFLVYSK 237 >3IRM-A nrPDB Length = 521 Score = 86.3 bits (212), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 26/173 (15%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTT------TSSVEGKQNLVIMGR 55 +R + +VAV ++ GIG +PW + + K+F+ +TT K+N V+MGR Sbjct: 20 LRAFSLVVAVDEHGGIGDGRSIPWN-VPEDMKFFRDLTTKLRGKNVKPSPAKRNAVVMGR 78 Query: 56 KTWFSIPEKNRPLKDRINIVLSRELK----------EPPRGAH-----FLAKSLDDALRL 100 KTW SIP K RPL R+N+VLS L E R H + L+ ALRL Sbjct: 79 KTWDSIPPKFRPLPGRLNVVLSSTLTTQHLLDGLPDEEKRNLHADSIVAVNGGLEQALRL 138 Query: 101 IEQPELASKVDMVWIVGGSSVYQEAMNQPG-HLRLFVTRIM---QEFESDTFF 149 + P ++ V+ +GG SVY EA+ P HL + R E FF Sbjct: 139 LASPNYTPSIETVYCIGGGSVYAEALRPPCVHLLQAIYRTTIRASESSCSVFF 191 >1ZDR-A nrPDB Length = 164 Score = 82.0 bits (201), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 60/182 (32%), Positives = 99/182 (54%), Gaps = 22/182 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ IVA+ +N IGK+ LPW L + YF+R+T ++ +MGRKT+ +I Sbjct: 2 ISHIVAMDENRVIGKDNRLPWH-LPADLAYFKRVTMGHAI-------VMGRKTFEAI--- 50 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R N+V++ P G L SL++ + I AS+ D V+I+GG+ +++ Sbjct: 51 GRPLPGRDNVVVTGNRSFRPEGCLVL-HSLEEVKQWI-----ASRADEVFIIGGAELFRA 104 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 M P RL+VT+I F DTF+P I +++++ PG E+ ++ F +YE Sbjct: 105 TM--PIVDRLYVTKIFASFPGDTFYPPISDDEWEIVSYTPG---GKDEKNPYEHAFIIYE 159 Query: 185 KK 186 +K Sbjct: 160 RK 161 >3JW3-A nrPDB Length = 168 Score = 77.0 bits (188), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 56/179 (31%), Positives = 94/179 (52%), Gaps = 23/179 (12%) Query: 8 IVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRP 67 +VA+ +N IGK+ +LPW L +E +Y ++ T + IMGRK + +I RP Sbjct: 12 MVAMDENRVIGKDNNLPWR-LPSELQYVKKTTMGHPL-------IMGRKNYEAI---GRP 60 Query: 68 LKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMN 127 L R NI+++R G +A S+++ EL + ++I+GG+ +Y + Sbjct: 61 LPGRRNIIVTRNEGYHVEGCE-VAHSVEEVF------ELCKNEEEIFIIGGAQIYDLFL- 112 Query: 128 QPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYEKK 186 P +L++T+I FE DTFFPE+D+ +K + G+ E+ Y + VYEK+ Sbjct: 113 -PYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGL---TDEKNPYTYYYHVYEKQ 167 >4KJL-A nrPDB Length = 160 Score = 74.7 bits (182), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 56/185 (30%), Positives = 88/185 (47%), Gaps = 29/185 (15%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ + IG +PWPPL + +F+R T VIMGR TW SI Sbjct: 2 ISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKP-------VIMGRHTWESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R NI+LS + R KS+D+A+ V + ++GG VY++ Sbjct: 52 GRPLPGRKNIILSSQPGTDDRVT--WVKSVDEAI------AACGDVPEIMVIGGGRVYEQ 103 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQE---EKGIKYKFE 181 + P +L++T I E E DT FP+ + ++ V SE + + Y FE Sbjct: 104 FL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWE------SVFSEFHDADAQNAHSYCFE 155 Query: 182 VYEKK 186 + E++ Sbjct: 156 ILERR 160 >4M7V-A nrPDB Length = 175 Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 57/183 (31%), Positives = 88/183 (48%), Gaps = 21/183 (11%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L I A + IGK G LPW L N+ K+F+ T N +++GR T+ + Sbjct: 10 LAAIWAQDEQGVIGKEGKLPWH-LPNDLKFFKEKTI-------HNTLVLGRATFEGM--G 59 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL +R IVL+ G + S+++ L ++ E + + GGS V++E Sbjct: 60 CRPLPNRTTIVLTSNPDYQAEGV-LVMHSVEEILAYADKYEGVTVIG-----GGSVVFKE 113 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 + P L+ T I + FE DTFFPEID ++ + PGV V E+ + +E Y Sbjct: 114 LI--PACDVLYRTMIHETFEGDTFFPEIDWSVWEKVATVPGV---VDEKNLYAHDYETYH 168 Query: 185 KKD 187 + D Sbjct: 169 RND 171 >3IA5-A nrPDB Length = 162 Score = 70.9 bits (172), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 51/147 (34%), Positives = 80/147 (54%), Gaps = 20/147 (13%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ N IG + +PW L E + F+R T GK ++MGR T+ SI Sbjct: 3 VSMIAALANNRVIGLDNKMPWH-LPAELQLFKRATL-----GKP--IVMGRNTFESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R+NIVLSR+ P G +A +L+DA+ A V+ + I+GG+++Y + Sbjct: 52 GRPLPGRLNIVLSRQTDYQPEGVTVVA-TLEDAVV------AAGDVEELMIIGGATIYNQ 104 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPE 151 + RL++T I E DT+FP+ Sbjct: 105 CLAAAD--RLYLTHIELTTEGDTWFPD 129 >3TQB-A nrPDB Length = 178 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 58/183 (31%), Positives = 97/183 (53%), Gaps = 31/183 (16%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + I A+ +N IG+N +LPW L + +F+ +T GK ++MGR+T+ SI Sbjct: 3 ITLIAAMDKNRLIGRNNELPW-HLPADLAHFKSITL-----GKP--IVMGRRTFDSI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALR-LIEQPELASKVDMVWIVGGSSVYQ 123 +PL R NIV++++ G SLDDAL L ++PE V I+GG+ +++ Sbjct: 52 GKPLPHRRNIVITQQKNLIIEGCDIFY-SLDDALSALTKEPE-------VIIIGGARIFK 103 Query: 124 EAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIK--YKFE 181 EA+ P ++ +T I FE D +FPE + ++K + S+++ E+ K Y F+ Sbjct: 104 EAL--PKADKMILTIINHSFEGDVYFPEWNDKEWK-------ITSQIKHERDEKNPYPFQ 154 Query: 182 VYE 184 E Sbjct: 155 FLE 157 >2JYB-A nrPDB Length = 162 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 43/160 (26%), Positives = 87/160 (54%), Gaps = 20/160 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L + A+++N IG++G+LPWP + + K ++ + V++GR T+ S+ + Sbjct: 3 LVSVAALAENRVIGRDGELPWPSIPADKKQYRSRVA-------DDPVVLGRTTFESMRDD 55 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVD--MVWIVGGSSVY 122 L IV+SR + A S+++A+ ++A+ +D +++GG+++Y Sbjct: 56 ---LPGSAQIVMSRSERSFSVDTAHRAASVEEAV------DIAASLDAETAYVIGGAAIY 106 Query: 123 QEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPE 162 A+ QP R+ ++R+ E+E DT++PE D +++L E Sbjct: 107 --ALFQPHLDRMVLSRVPGEYEGDTYYPEWDAAEWELDAE 144 >4M2X-A nrPDB Length = 162 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 54/186 (29%), Positives = 85/186 (45%), Gaps = 32/186 (17%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + I A + + IG+ GD+PW L + +F+ +T + ++MGR+TW S+P K Sbjct: 5 VGLIWAQATSGVIGRGGDIPWR-LPEDQAHFREITM-------GHTIVMGRRTWDSLPAK 56 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R N+VLSR+ GA + SL++AL PE W++GG VY Sbjct: 57 VRPLPGRRNVVLSRQADFMASGAEVVG-SLEEAL---TSPE-------TWVIGGGQVY-- 103 Query: 125 AMNQPGHLRLFVTRI---MQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQ-EEKGIKYKF 180 A+ P R VT + + D P +D + G E + G++Y+ Sbjct: 104 ALALPYATRCEVTEVDIGLPREAGDALAPVLD-------ETWRGETGEWRFSRSGLRYRL 156 Query: 181 EVYEKK 186 Y + Sbjct: 157 YSYHRS 162 >2W9S-A nrPDB Length = 161 Score = 63.5 bits (153), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 51/165 (30%), Positives = 83/165 (50%), Gaps = 23/165 (13%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ IVA + IG LPW L N+ K+ +++TT N ++M RKT+ SI Sbjct: 3 LSIIVAHDKQRVIGYQNQLPWH-LPNDLKHIKQLTTG-------NTLVMARKTFESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL +R N+VL+ + A F + +D L E EL+ V +I GG ++Y+ Sbjct: 52 GKPLPNRRNVVLTNQ-------ASFHHEGVDVINSLDEIKELSGHV---FIFGGQTLYEA 101 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSE 169 ++Q +++T I +F+ DTFFP +++ G L E Sbjct: 102 MIDQVD--DMYITVIDGKFQGDTFFPPYTFEDWEVESSVEGQLDE 144 >3Q1H-A nrPDB Length = 163 Score = 63.2 bits (152), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 55/185 (29%), Positives = 88/185 (47%), Gaps = 30/185 (16%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ + IG +PW L + +F+R T V IMGRKT+ SI Sbjct: 6 ISLIAALAADRVIGMENAMPWH-LPADLAWFKRNTLNKPV-------IMGRKTFESI--- 54 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R+NIV+S + R A S+++AL A + V ++GG VY++ Sbjct: 55 GRPLPGRLNIVISSQPGTDERVT--WAASIEEAL------AFAGNAEEVMVMGGGRVYKQ 106 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQ---EEKGIKYKFE 181 +++ R+++T I E DT FP+ + E+ V SE E Y FE Sbjct: 107 FLDRAN--RMYLTHIDAEVGGDTHFPDYE------PDEWESVFSEFHDADEANSHSYCFE 158 Query: 182 VYEKK 186 + E++ Sbjct: 159 ILERR 163 >2W3W-A nrPDB Length = 167 Score = 62.8 bits (151), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 54/184 (29%), Positives = 85/184 (46%), Gaps = 26/184 (14%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + + A S + IG+ GD+PW + + F+ +T + VIMGR+TW S+P K Sbjct: 6 VGLVWAQSTSGVIGRGGDIPWS-VPEDLTRFKEVTM-------GHTVIMGRRTWESLPAK 57 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R N+V+SR GA +A SL+ AL A W++GG+ +Y Sbjct: 58 VRPLPGRRNVVVSRRPDFVAEGAR-VAGSLEAAL------AYAGSDPAPWVIGGAQIYLL 110 Query: 125 AMNQPGHLRLFVTRI---MQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 181 A+ P R VT I ++ + D P +D E+ + G++Y+F Sbjct: 111 AL--PHATRCEVTEIEIDLRRDDDDALAPALDDSWVGETGEW------LASRSGLRYRFH 162 Query: 182 VYEK 185 Y + Sbjct: 163 SYRR 166 >4OSG-A nrPDB Length = 165 Score = 60.8 bits (146), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 38/189 (20%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ + IG +PW L + +F+R T V +MGR TW SI Sbjct: 2 ISLIAALAVDRVIGMENAMPWN-LPADLAWFKRNTLNKPV-------VMGRLTWESI--- 50 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELA----SKVDMVWIVGGSS 120 RPL R NIV+S + DD ++ + E A V+ + ++GG Sbjct: 51 GRPLPGRKNIVISSK------------PGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGR 98 Query: 121 VYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQE---EKGIK 177 VY++ + P +L++T I E E DT FP+ D E+ V SE + + Sbjct: 99 VYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYDPD------EWESVFSEFHDADAQNSHS 150 Query: 178 YKFEVYEKK 186 Y FE+ E++ Sbjct: 151 YCFEILERR 159 >3LG4-A nrPDB Length = 168 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 83/165 (50%), Gaps = 23/165 (13%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ +VA IG LPW L N+ K++++++T ++ +MGRKT+ SI Sbjct: 3 LSILVAHDLQRVIGFENQLPWH-LPNDLKHYKKLSTGHTL-------VMGRKTFESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL +R N+VL+ + G + S++D +L V+I+GG ++++E Sbjct: 52 GKPLPNRRNVVLTSDTSFNVEGVDVI-HSIEDIYQLPGH---------VFIIGGQTLFEE 101 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSE 169 +++ +++T I +F DTFFP +++ G L E Sbjct: 102 MIDKVD--DMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDE 144 >6CXM-A nrPDB Length = 164 Score = 55.8 bits (133), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 29/182 (15%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + I A S + IG++ +PW L + F+ MT + V+MGR TW S+P Sbjct: 11 MRLIWAQSTSGIIGRDNSIPWR-LPEDLARFKEMTM-------GHPVVMGRLTWESLPAS 62 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R NIV++R+ GA + L ++P+ W++GG+ +Y Sbjct: 63 VRPLPGRRNIVVTRDADYRAEGAEVVTD-------LPDEPD-------AWVIGGAQIYAM 108 Query: 125 AMNQPGHLRLFVTRI-MQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVY 183 A+ + + I + + D P +D E+ S G++++F Y Sbjct: 109 ALARADRCEVTEVDIALTPLDGDARAPVLDDSWVATTGEWQTSTS------GLRFRFCSY 162 Query: 184 EK 185 + Sbjct: 163 RR 164 >6E4E-A nrPDB Length = 182 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 23/165 (13%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ +VA IG LPW L N+ K+ ++++T ++ +MGRKT+ SI Sbjct: 26 LSILVAHDLQRVIGFENQLPWH-LPNDLKHVKKLSTGHTL-------VMGRKTFESI--- 74 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL +R N+VL+ + G + S++D +L V+I GG ++++E Sbjct: 75 GKPLPNRRNVVLTSDTSFNVEGVDVI-HSIEDIYQLPGH---------VFIFGGQTLFEE 124 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSE 169 +++ +++T I +F DTFFP +++ G L E Sbjct: 125 MIDKVD--DMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDE 167 >2L28-A nrPDB Length = 162 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/176 (27%), Positives = 85/176 (48%), Gaps = 33/176 (18%) Query: 17 IGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVL 76 IGK+G LPW L ++ YF+ T GK ++++GR+T+ S P+ RPL +R N+VL Sbjct: 13 IGKDGHLPWH-LPDDLHYFRAQTV-----GK--IMVVGRRTYESFPK--RPLPERTNVVL 62 Query: 77 SRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFV 136 + + +GA + + P+ ++V I GG+ ++ + L V Sbjct: 63 THQEDYQAQGAVVVHDVAAVFAYAKQHPDQ----ELV-IAGGAQIFTAFKDDVD--TLLV 115 Query: 137 TRIMQEFESDTFFPEIDLGKYKLLP----EYPGVLSEVQEEK--GIKYKFEVYEKK 186 TR+ FE DT K++P ++ V S E+ + + +EV++KK Sbjct: 116 TRLAGSFEGDT----------KMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQKK 161 >5ECC-A nrPDB Length = 157 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 67/148 (45%), Gaps = 19/148 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ +VA+S+N IG D+PW + E F+ +T +++GRKT+ E Sbjct: 3 LSLMVAISKNGVIGNGPDIPWSA-KGEQLLFKAIT-------YNQWLLVGRKTF----ES 50 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 L +R V++R + S+ DAL L D V + GG +Y+ Sbjct: 51 MGALPNRKYAVVTRSSFTSDNENVLIFPSIKDALT-----NLKKITDHVIVSGGGEIYKS 105 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEI 152 ++Q L ++ I E E D +FPEI Sbjct: 106 LIDQVDTLH--ISTIDIEPEGDVYFPEI 131 >3IX9-A nrPDB Length = 190 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 75/161 (46%), Gaps = 19/161 (11%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS 60 M + + I A + IGK+ LPW L E ++F+ T ++ +MGR T+ Sbjct: 21 MTKKIVAIWAQDEEGVIGKDNRLPWY-LPAELQHFKETTLNHAI-------LMGRVTFDG 72 Query: 61 IPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSS 120 + R L R ++L+R +E G + D +++ +++ ++IVGG Sbjct: 73 M--GRRLLPKRETLILTRNPEEKIDGV----ATFHDVQSVLDW--YSAQEKNLYIVGGKQ 124 Query: 121 VYQEAMNQPGHLRLFVTRIMQEFESDTFFP-EIDLGKYKLL 160 ++Q +P + VT I E DT+FP E DL ++ + Sbjct: 125 IFQAF--EPYLDEVIVTHIHARVEGDTYFPAEFDLSLFETV 163 >5DXV-A nrPDB Length = 156 Score = 42.7 bits (99), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 34/98 (34%), Positives = 48/98 (48%), Gaps = 13/98 (13%) Query: 51 VIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKV 110 VIMGR TW SI RPL R NI+LS + R KS+D+A+ V Sbjct: 58 VIMGRHTWESI---GRPLPGRKNIILSSQPGTDDRVT--WVKSVDEAI------AACGDV 106 Query: 111 DMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTF 148 + ++GG VY++ + P +L++T I E S F Sbjct: 107 PEIMVIGGGRVYEQFL--PKAQKLYLTHIDAEGHSYCF 142 >1CZ3-A nrPDB Length = 168 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 17/106 (16%) Query: 42 SSVEGKQNL---------VIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPR-GAHFLA 91 SS E ++N V+MGR T+ E RPL +R+N+VL+R K F Sbjct: 23 SSFEDRKNFRKITTEIGNVVMGRITF---EEIGRPLPERLNVVLTRRPKTSNNPSLVFFN 79 Query: 92 KSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVT 137 S D ++ +E + V ++GG +V+ E + + LFVT Sbjct: 80 GSPADVVKFLE----GKGYERVAVIGGKTVFTEFLREKLVDELFVT 121 >1TYG-A nrPDB Length = 253 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%) Query: 135 FVTRIMQEFESD--TFFPEIDLGKYKLLPEYPGV 166 F R M FE+ F ++DL KY LLP G Sbjct: 40 FAVRRMNIFEASQPNFLEQLDLSKYTLLPNTAGA 73 >1Q8R-A nrPDB Length = 120 Score = 27.3 bits (59), Expect = 3.8, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 13/25 (52%) Query: 23 LPWPPLRNEFKYFQRMTTTSSVEGK 47 LPWPP N + R T S EG+ Sbjct: 8 LPWPPSNNRYYRHNRGRTHVSAEGQ 32 >3T8I-A nrPDB Length = 306 Score = 26.9 bits (58), Expect = 5.2, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 54 GRKTWFSIPEKN-RPLKDRINIVLSRELKEPPRGAHFLAKS--LDDALRLIEQPELASKV 110 G W + PE N RP K+ + R KE LA S + AL ++ P + +V Sbjct: 83 GMSNW-NYPEPNKRPEKEHAIDAILRLSKEHEGELEILAISPLTNIALAYLKDPSVVKRV 141 Query: 111 DMVWIVGGS 119 +WI+GG+ Sbjct: 142 KKIWIMGGA 150 >3EVG-A nrPDB Length = 275 Score = 26.9 bits (58), Expect = 5.5, Method: Compositional matrix adjust. Identities = 12/48 (25%), Positives = 23/48 (47%), Gaps = 2/48 (4%) Query: 108 SKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLG 155 S +M W+ S ++N R+ + R ++ T+ P++DLG Sbjct: 214 STHEMYWVSNASGNIVSSVNMIS--RMLINRFTMRYKKATYEPDVDLG 259 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3D84-X nrPDB 265 1e-71 3GYF-A nrPDB 259 4e-70 1DR5-A nrPDB 249 3e-67 5T0L-A nrPDB 208 9e-55 3VCO-A nrPDB 200 4e-52 4ECK-A nrPDB 191 2e-49 4KJL-A nrPDB 186 5e-48 3JW3-A nrPDB 184 2e-47 1ZDR-A nrPDB 184 2e-47 4DP3-A nrPDB 183 4e-47 3Q1H-A nrPDB 181 2e-46 1J3I-A nrPDB 181 2e-46 4OSG-A nrPDB 181 2e-46 4M7V-A nrPDB 179 6e-46 3K2H-A nrPDB 178 1e-45 3CD2-A nrPDB 174 2e-44 1QZF-A nrPDB 172 1e-43 3IA5-A nrPDB 171 3e-43 2BL9-A nrPDB 169 6e-43 3TQB-A nrPDB 169 7e-43 2W9S-A nrPDB 164 2e-41 3IRM-A nrPDB 164 3e-41 3LG4-A nrPDB 162 9e-41 3RG9-A nrPDB 160 3e-40 6E4E-A nrPDB 160 3e-40 4M2X-A nrPDB 159 5e-40 1IA3-A nrPDB 158 1e-39 6CXM-A nrPDB 156 6e-39 3EEM-A nrPDB 155 1e-38 2W3W-A nrPDB 154 3e-38 3IX9-A nrPDB 150 4e-37 2JYB-A nrPDB 147 2e-36 2L28-A nrPDB 135 9e-33 5ECC-A nrPDB 129 5e-31 5DXV-A nrPDB 119 6e-28 1CZ3-A nrPDB 89 1e-18 Sequences not found previously or not previously below threshold: 1JUV-A nrPDB 58 2e-09 3JTW-A nrPDB 55 2e-08 3KY8-A nrPDB 38 0.003 2XW7-A nrPDB 35 0.022 2P4G-A nrPDB 33 0.100 2HXV-A nrPDB 32 0.14 4HA7-A nrPDB 30 0.50 4J1O-A nrPDB 30 0.61 6BKF-A nrPDB 30 0.77 3FZA-A nrPDB 29 1.1 3POC-A nrPDB 29 1.1 2AEG-A nrPDB 28 1.7 4K8U-A nrPDB 28 2.0 3H0M-B nrPDB 27 3.5 1UP7-A nrPDB 27 3.5 3T8I-A nrPDB 27 4.4 5AMB-A nrPDB 27 4.6 6AQE-A nrPDB 27 6.7 1OJM-A nrPDB 27 6.8 3VNN-A nrPDB 26 9.0 >3D84-X nrPDB Length = 186 Score = 265 bits (676), Expect = 1e-71, Method: Composition-based stats. Identities = 186/186 (100%), Positives = 186/186 (100%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 61 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI Sbjct: 1 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 60 Query: 62 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV 121 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV Sbjct: 61 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV 120 Query: 122 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 181 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE Sbjct: 121 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 180 Query: 182 VYEKKD 187 VYEKKD Sbjct: 181 VYEKKD 186 >3GYF-A nrPDB Length = 187 Score = 259 bits (663), Expect = 4e-70, Method: Composition-based stats. Identities = 168/187 (89%), Positives = 180/187 (96%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS 60 MV LNCIVAVSQNMGIGKNGDLPWPPLRNEF+YFQRMTTTSSVEGKQNLVIMG+KTWFS Sbjct: 1 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS 60 Query: 61 IPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSS 120 IPEKNRPLK RIN+VLSRELKEPP+GAHFL++SLDDAL+L EQPELA+KVDMVWIVGGSS Sbjct: 61 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS 120 Query: 121 VYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKF 180 VY+EAMN PGHL+LFVTRIMQ+FESDTFFPEIDL KYKLLPEYPGVLS+VQEEKGIKYKF Sbjct: 121 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF 180 Query: 181 EVYEKKD 187 EVYEK D Sbjct: 181 EVYEKND 187 >1DR5-A nrPDB Length = 189 Score = 249 bits (637), Expect = 3e-67, Method: Composition-based stats. Identities = 142/185 (76%), Positives = 164/185 (88%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 61 VR LN IVAV QNMGIGK+G+LPWPPLRNE+KYFQRMT+TS VEGKQN VIMG+KTWFSI Sbjct: 1 VRSLNSIVAVCQNMGIGKDGNLPWPPLRNEYKYFQRMTSTSHVEGKQNAVIMGKKTWFSI 60 Query: 62 PEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSV 121 PEKNRPLKDRINIVLSRELKE P+GAH+L+KSLDDAL L++ PEL SKVDMVWIVGG++V Sbjct: 61 PEKNRPLKDRINIVLSRELKEAPKGAHYLSKSLDDALALLDSPELKSKVDMVWIVGGTAV 120 Query: 122 YQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 181 Y+ AM +P + RLFVTRI+ EFESDTFFPEID +KLL EYPGV +++QEE GI+YKFE Sbjct: 121 YKAAMEKPINHRLFVTRILHEFESDTFFPEIDYKDFKLLTEYPGVPADIQEEDGIQYKFE 180 Query: 182 VYEKK 186 VY+K Sbjct: 181 VYQKS 185 >5T0L-A nrPDB Length = 566 Score = 208 bits (530), Expect = 9e-55, Method: Composition-based stats. Identities = 75/208 (36%), Positives = 109/208 (52%), Gaps = 23/208 (11%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQ-NLVIMGRKTWF 59 M +P+ +VA++ GIG N LPWP L +FK+F R+T T+ E + N V+MGRKTW Sbjct: 1 MQKPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPEEASRFNAVVMGRKTWE 60 Query: 60 SIPEKNRPLKDRINIVLSRELKEPPRGAH----------FLAKSLDDALRLIEQPELASK 109 S+P K RPL DR+NIV+S LKE A + SL AL L+E+ E Sbjct: 61 SMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEE-EYKDS 119 Query: 110 VDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKY-----------K 158 VD +++VGG+ +Y+ A++ L++TR+ +EF D FFP Sbjct: 120 VDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKSTAAEKDN 179 Query: 159 LLPEYPGVLSEVQEEKGIKYKFEVYEKK 186 P +S+ + G+ Y F V EK+ Sbjct: 180 EATYRPIFISKTFSDNGVPYDFVVLEKR 207 >3VCO-A nrPDB Length = 201 Score = 200 bits (508), Expect = 4e-52, Method: Composition-based stats. Identities = 76/181 (41%), Positives = 116/181 (64%), Gaps = 5/181 (2%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 LN +VAVS+N GIGK G LPW ++ + ++F+ +TT + G +N V+MGR TW SIPE Sbjct: 23 LNVVVAVSENWGIGKGGGLPWK-IKKDMEFFKTVTT-KAHPGLKNAVVMGRVTWESIPES 80 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PLKDRINIV+S L P + SL+ A+ L+ E +S VD V+I+GG +Y+E Sbjct: 81 FKPLKDRINIVVSSTLSHAPSFVQVV-PSLNAAIDLLYNEEFSSIVDEVFIIGGYRLYKE 139 Query: 125 AMNQPGH-LRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVY 183 A+ Q + +R++ T I+ E + DT+FP++D K K + + P + ++ E G +KF VY Sbjct: 140 ALKQSIYPVRIYCTHILSEVDCDTYFPKVDWDKLKKV-DLPDIPADTFTENGFTFKFCVY 198 Query: 184 E 184 + Sbjct: 199 D 199 >4ECK-A nrPDB Length = 610 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 109/252 (43%), Gaps = 67/252 (26%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQ------------ 48 M +P+ +VA++ GIG N LPWP L +FK+F R+T T+ E + Sbjct: 1 MQKPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPEEASRLNGWLPRKFAKT 60 Query: 49 --------------NLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAH------ 88 N V+MGRKTW S+P K RPL DR+NIV+S LKE A Sbjct: 61 GDSGLPSPSVGKRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEG 120 Query: 89 ----FLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFE 144 + SL AL L+E+ E VD +++VGG+ +Y+ A++ L++TR+ +EF Sbjct: 121 QQRVRVCASLPAALSLLEE-EYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFP 179 Query: 145 SDTFFPEIDLGKY------------------------------KLLPEYPGVLSEVQEEK 174 D FFP P +S+ + Sbjct: 180 CDVFFPAFPGDDILSNKSTAAQAAAPAESVFVPFCPELGREKDNEATYRPIFISKTFSDN 239 Query: 175 GIKYKFEVYEKK 186 G+ Y F V EK+ Sbjct: 240 GVPYDFVVLEKR 251 >4KJL-A nrPDB Length = 160 Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats. Identities = 53/182 (29%), Positives = 86/182 (47%), Gaps = 23/182 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ + IG +PWPPL + +F+R T VIMGR TW SI Sbjct: 2 ISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKP-------VIMGRHTWESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R NI+LS + R KS+D+A+ V + ++GG VY++ Sbjct: 52 GRPLPGRKNIILSSQPGTDDR--VTWVKSVDEAIAA------CGDVPEIMVIGGGRVYEQ 103 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 + P +L++T I E E DT FP+ + ++ + + + Y FE+ E Sbjct: 104 FL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVF---SEFHDADAQNAHSYCFEILE 158 Query: 185 KK 186 ++ Sbjct: 159 RR 160 >3JW3-A nrPDB Length = 168 Score = 184 bits (467), Expect = 2e-47, Method: Composition-based stats. Identities = 56/183 (30%), Positives = 96/183 (52%), Gaps = 23/183 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ +VA+ +N IGK+ +LPW L +E +Y ++ T +IMGRK + +I Sbjct: 9 VSFMVAMDENRVIGKDNNLPWR-LPSELQYVKKTTMGHP-------LIMGRKNYEAI--- 57 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R NI+++R G +A S+++ EL + ++I+GG+ +Y Sbjct: 58 GRPLPGRRNIIVTRNEGYHVEGCE-VAHSVEEVF------ELCKNEEEIFIIGGAQIYDL 110 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 + P +L++T+I FE DTFFPE+D+ +K + G+ E+ Y + VYE Sbjct: 111 FL--PYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGL---TDEKNPYTYYYHVYE 165 Query: 185 KKD 187 K+ Sbjct: 166 KQQ 168 >1ZDR-A nrPDB Length = 164 Score = 184 bits (467), Expect = 2e-47, Method: Composition-based stats. Identities = 59/182 (32%), Positives = 98/182 (53%), Gaps = 22/182 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ IVA+ +N IGK+ LPW L + YF+R+T ++MGRKT+ +I Sbjct: 2 ISHIVAMDENRVIGKDNRLPWH-LPADLAYFKRVTMGH-------AIVMGRKTFEAI--- 50 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R N+V++ P G + SL++ + I AS+ D V+I+GG+ +++ Sbjct: 51 GRPLPGRDNVVVTGNRSFRPEGC-LVLHSLEEVKQWI-----ASRADEVFIIGGAELFRA 104 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 M P RL+VT+I F DTF+P I +++++ PG E+ ++ F +YE Sbjct: 105 TM--PIVDRLYVTKIFASFPGDTFYPPISDDEWEIVSYTPG---GKDEKNPYEHAFIIYE 159 Query: 185 KK 186 +K Sbjct: 160 RK 161 >4DP3-A nrPDB Length = 608 Score = 183 bits (464), Expect = 4e-47, Method: Composition-based stats. Identities = 58/202 (28%), Positives = 97/202 (48%), Gaps = 38/202 (18%) Query: 15 MGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGK--------------------------- 47 G+G G LPW + + KYF+ +TT + Sbjct: 38 RGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKETVDNVNDMPNSKK 97 Query: 48 -QNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPP-RGAHFLAKSLDDALRLIEQPE 105 QN+V+MGR W SIP+K +PL +RIN++LSR LK+ ++ ++D + L+ + Sbjct: 98 LQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLN 157 Query: 106 LASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPG 165 +I+GGS VYQE + + +++ TRI +E D FFPEI+ +Y+++ Sbjct: 158 YYK----CFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIIS---- 209 Query: 166 VLSEVQEEKGIKYKFEVYEKKD 187 +S+V F +Y+K + Sbjct: 210 -VSDVYTSNNTTLDFIIYKKTN 230 >3Q1H-A nrPDB Length = 163 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 51/182 (28%), Positives = 88/182 (48%), Gaps = 24/182 (13%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ + IG +PW L + +F+R T VIMGRKT+ SI Sbjct: 6 ISLIAALAADRVIGMENAMPWH-LPADLAWFKRNTLNKP-------VIMGRKTFESI--- 54 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R+NIV+S + R A S+++AL A + V ++GG VY++ Sbjct: 55 GRPLPGRLNIVISSQPGTDER--VTWAASIEEALA------FAGNAEEVMVMGGGRVYKQ 106 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 +++ R+++T I E DT FP+ + +++ + + E Y FE+ E Sbjct: 107 FLDR--ANRMYLTHIDAEVGGDTHFPDYEPDEWESVF---SEFHDADEANSHSYCFEILE 161 Query: 185 KK 186 ++ Sbjct: 162 RR 163 >1J3I-A nrPDB Length = 280 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 38/202 (18%) Query: 15 MGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGK--------------------------- 47 G+G G LPW + KYF +TT + Sbjct: 38 RGLGNKGVLPWKCNSLDMKYFCAVTTYVNESKYEKLKYKRCKYLNKETVDNVNDMPNSKK 97 Query: 48 -QNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPP-RGAHFLAKSLDDALRLIEQPE 105 QN+V+MGR +W SIP+K +PL +RIN++LSR LK+ ++ ++D + L+ + Sbjct: 98 LQNVVVMGRTSWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLN 157 Query: 106 LASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPG 165 +I+GGS VYQE + + +++ TRI +E D FFPEI+ +Y+++ Sbjct: 158 YYK----CFIIGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIIS---- 209 Query: 166 VLSEVQEEKGIKYKFEVYEKKD 187 +S+V F +Y+K + Sbjct: 210 -VSDVYTSNNTTLDFIIYKKTN 230 >4OSG-A nrPDB Length = 165 Score = 181 bits (458), Expect = 2e-46, Method: Composition-based stats. Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 24/182 (13%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ + IG +PW L + +F+R T V+MGR TW SI Sbjct: 2 ISLIAALAVDRVIGMENAMPWN-LPADLAWFKRNTLNKP-------VVMGRLTWESI--- 50 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R NIV+S + R S+++A+ V+ + ++GG VY++ Sbjct: 51 GRPLPGRKNIVISSKPGSDDR--VQWVSSVEEAIAA------CGDVEEIMVIGGGRVYEQ 102 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 + P +L++T I E E DT FP+ D +++ + + + Y FE+ E Sbjct: 103 FL--PKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVF---SEFHDADAQNSHSYCFEILE 157 Query: 185 KK 186 ++ Sbjct: 158 RR 159 >4M7V-A nrPDB Length = 175 Score = 179 bits (454), Expect = 6e-46, Method: Composition-based stats. Identities = 57/183 (31%), Positives = 88/183 (48%), Gaps = 21/183 (11%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L I A + IGK G LPW L N+ K+F+ T N +++GR T+ + Sbjct: 10 LAAIWAQDEQGVIGKEGKLPWH-LPNDLKFFKEKTI-------HNTLVLGRATFEGM--G 59 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL +R IVL+ G + S+++ L ++ E + + GGS V++E Sbjct: 60 CRPLPNRTTIVLTSNPDYQAEGV-LVMHSVEEILAYADKYEGVTVIG-----GGSVVFKE 113 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 + P L+ T I + FE DTFFPEID ++ + PGV V E+ + +E Y Sbjct: 114 LI--PACDVLYRTMIHETFEGDTFFPEIDWSVWEKVATVPGV---VDEKNLYAHDYETYH 168 Query: 185 KKD 187 + D Sbjct: 169 RND 171 >3K2H-A nrPDB Length = 511 Score = 178 bits (451), Expect = 1e-45, Method: Composition-based stats. Identities = 62/191 (32%), Positives = 108/191 (56%), Gaps = 21/191 (10%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSS------VEGKQNLVIMGRKTW 58 L VAV+ N IG +PWP + ++F++ + TT QN+VI GRKT+ Sbjct: 11 LTIFVAVALNKVIGHKNQIPWPHITHDFRFLRNGTTYIPPEVLSKNPDIQNVVIFGRKTY 70 Query: 59 FSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKV--DMVWIV 116 SIP+ + PLK+RIN++LSR +KE P + + L A+R +L + V + ++I+ Sbjct: 71 ESIPKASLPLKNRINVILSRTVKEVP--GCLVYEDLSTAIR-----DLRANVPHNKIFIL 123 Query: 117 GGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGI 176 GGS +Y+E ++ ++++TR+ +E+ DT+FP+I +++ P ++ + Sbjct: 124 GGSFLYKEVLDNGLCDKIYLTRLNKEYPGDTYFPDI-PDTFEITAISPTFSTDF-----V 177 Query: 177 KYKFEVYEKKD 187 Y F +YE+KD Sbjct: 178 SYDFVIYERKD 188 >3CD2-A nrPDB Length = 206 Score = 174 bits (441), Expect = 2e-44, Method: Composition-based stats. Identities = 65/202 (32%), Positives = 107/202 (52%), Gaps = 19/202 (9%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGK---QNLVIMGRKTW 58 + L IVA++ + GIG++ LPW L+ E YF+R+T+ N+V+MGRKTW Sbjct: 4 QKSLTLIVALTTSYGIGRSNSLPWK-LKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTW 62 Query: 59 FSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQ---PELASKVDMVWI 115 SIP + RPLK RIN+V++R AKSLD AL L+ + E + +++ +++ Sbjct: 63 ESIPLQFRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFV 122 Query: 116 VGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFP-EIDLGKYKLL---------PEYPG 165 +GG+ +Y+ AM+ P R+ T I ++ D FFP + ++ + + G Sbjct: 123 IGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVG 182 Query: 166 --VLSEVQEEKGIKYKFEVYEK 185 V E G Y+FE++ + Sbjct: 183 TKVPHGKINEDGFDYEFEMWTR 204 >1QZF-A nrPDB Length = 521 Score = 172 bits (435), Expect = 1e-43, Method: Composition-based stats. Identities = 60/188 (31%), Positives = 106/188 (56%), Gaps = 15/188 (7%) Query: 3 RPLNCIVAVS-QNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSI 61 + ++ +VA S + GIG NG LPW + + K+F ++T K+N +IMGRKTW SI Sbjct: 4 KNVSIVVAASVLSSGIGINGQLPWS-ISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSI 62 Query: 62 PEKNRPLKDRINIVLSRELKEPPRGAHFLA-KSLDDALRLIEQPELASKVDMVWIVGGSS 120 RPLK+RI +V+S L + + + ++L+D++ E ++ +++ GG S Sbjct: 63 GR--RPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSI---ENLMNDDSIENIFVCGGES 117 Query: 121 VYQEAMNQPGHLRLFVTRI-MQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYK 179 +Y++A+ R+++TR+ +++ E DT+FPEI P +S+ K I Y Sbjct: 118 IYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPET------FLPVYMSQTFCTKNISYD 171 Query: 180 FEVYEKKD 187 F ++EK++ Sbjct: 172 FMIFEKQE 179 >3IA5-A nrPDB Length = 162 Score = 171 bits (432), Expect = 3e-43, Method: Composition-based stats. Identities = 53/181 (29%), Positives = 90/181 (49%), Gaps = 23/181 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 ++ I A++ N IG + +PW L E + F+R T ++MGR T+ SI Sbjct: 3 VSMIAALANNRVIGLDNKMPWH-LPAELQLFKRATLGKP-------IVMGRNTFESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R+NIVLSR+ P G +A +L+DA+ A V+ + I+GG+++Y + Sbjct: 52 GRPLPGRLNIVLSRQTDYQPEGVTVVA-TLEDAVVA------AGDVEELMIIGGATIYNQ 104 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 + RL++T I E DT+FP+ + ++ E ++ Y+F + E Sbjct: 105 CLAA--ADRLYLTHIELTTEGDTWFPDYEQYNWQ---EIEHESYAADDKNPHNYRFSLLE 159 Query: 185 K 185 + Sbjct: 160 R 160 >2BL9-A nrPDB Length = 238 Score = 169 bits (429), Expect = 6e-43, Method: Composition-based stats. Identities = 61/210 (29%), Positives = 95/210 (45%), Gaps = 48/210 (22%) Query: 15 MGIGKNGDLPWPPLRNEFKYFQRMTT---------------------------------- 40 G+G G LPW + KYF +TT Sbjct: 37 RGLGNKGTLPWKCNSVDMKYFSSVTTYVDESKYEKLKWKRERYLRMEASQGGGDNTSGGD 96 Query: 41 ----TSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSREL-KEPPRGAHFLAKSLD 95 + + QN+V+MGR +W SIP++ +PL +RIN+VLS+ L KE + F+ S+D Sbjct: 97 NTHGGDNADKLQNVVVMGRSSWESIPKQYKPLPNRINVVLSKTLTKEDVKEKVFIIDSID 156 Query: 96 DALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLG 155 D + K +I+GG+ VY+E +++ +++ TRI + D FFPE D Sbjct: 157 D----LLLLLKKLKYYKCFIIGGAQVYRECLSRNLIKQIYFTRINGAYPCDVFFPEFDES 212 Query: 156 KYKLLPEYPGVLSEVQEEKGIKYKFEVYEK 185 ++++ +SEV KG F VY K Sbjct: 213 EFRVTS-----VSEVYNSKGTTLDFLVYSK 237 >3TQB-A nrPDB Length = 178 Score = 169 bits (428), Expect = 7e-43, Method: Composition-based stats. Identities = 51/181 (28%), Positives = 91/181 (50%), Gaps = 23/181 (12%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + I A+ +N IG+N +LPW L + +F+ +T ++MGR+T+ SI Sbjct: 3 ITLIAAMDKNRLIGRNNELPWH-LPADLAHFKSITLGKP-------IVMGRRTFDSI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL R NIV++++ G SLDDAL + +K V I+GG+ +++E Sbjct: 52 GKPLPHRRNIVITQQKNLIIEGCDIFY-SLDDALSAL------TKEPEVIIIGGARIFKE 104 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 A+ P ++ +T I FE D +FPE + ++K+ + + E E+ ++F Sbjct: 105 AL--PKADKMILTIINHSFEGDVYFPEWNDKEWKITSQ---IKHERDEKNPYPFQFLELR 159 Query: 185 K 185 + Sbjct: 160 R 160 >2W9S-A nrPDB Length = 161 Score = 164 bits (416), Expect = 2e-41, Method: Composition-based stats. Identities = 50/182 (27%), Positives = 87/182 (47%), Gaps = 26/182 (14%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ IVA + IG LPW L N+ K+ +++TT N ++M RKT+ SI Sbjct: 3 LSIIVAHDKQRVIGYQNQLPWH-LPNDLKHIKQLTTG-------NTLVMARKTFESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL +R N+VL+ + G + SLD+ L V+I GG ++Y+ Sbjct: 52 GKPLPNRRNVVLTNQASFHHEGVDVIN-SLDEIKELSGH---------VFIFGGQTLYEA 101 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 ++Q +++T I +F+ DTFFP +++ G ++ E+ I + F Sbjct: 102 MIDQ--VDDMYITVIDGKFQGDTFFPPYTFEDWEVESSVEG---QLDEKNTIPHTFLHLV 156 Query: 185 KK 186 ++ Sbjct: 157 RR 158 >3IRM-A nrPDB Length = 521 Score = 164 bits (414), Expect = 3e-41, Method: Composition-based stats. Identities = 62/212 (29%), Positives = 91/212 (42%), Gaps = 35/212 (16%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTT------TSSVEGKQNLVIMGR 55 +R + +VAV ++ GIG +PW + + K+F+ +TT K+N V+MGR Sbjct: 20 LRAFSLVVAVDEHGGIGDGRSIPWN-VPEDMKFFRDLTTKLRGKNVKPSPAKRNAVVMGR 78 Query: 56 KTWFSIPEKNRPLKDRINIVLSRELKEP---------------PRGAHFLAKSLDDALRL 100 KTW SIP K RPL R+N+VLS L + L+ ALRL Sbjct: 79 KTWDSIPPKFRPLPGRLNVVLSSTLTTQHLLDGLPDEEKRNLHADSIVAVNGGLEQALRL 138 Query: 101 IEQPELASKVDMVWIVGGSSVYQEAMNQPGH---LRLFVTRI-MQEFESDTFF--PEIDL 154 + P ++ V+ +GG SVY EA+ P ++ T I E FF PE Sbjct: 139 LASPNYTPSIETVYCIGGGSVYAEALRPPCVHLLQAIYRTTIRASESSCSVFFRVPESGT 198 Query: 155 G-----KYKLLPEYPGVLSEVQEEKGIKYKFE 181 +++ + S KY FE Sbjct: 199 EAAAGIEWQRETISEELTS--ANGNETKYYFE 228 >3LG4-A nrPDB Length = 168 Score = 162 bits (410), Expect = 9e-41, Method: Composition-based stats. Identities = 47/182 (25%), Positives = 89/182 (48%), Gaps = 26/182 (14%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ +VA IG LPW L N+ K++++++T ++MGRKT+ SI Sbjct: 3 LSILVAHDLQRVIGFENQLPWH-LPNDLKHYKKLSTGH-------TLVMGRKTFESI--- 51 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL +R N+VL+ + G + S++D +L V+I+GG ++++E Sbjct: 52 GKPLPNRRNVVLTSDTSFNVEGVDVI-HSIEDIYQLPGH---------VFIIGGQTLFEE 101 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 +++ +++T I +F DTFFP +++ G ++ E+ I + F Sbjct: 102 MIDK--VDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEG---KLDEKNTIPHTFLHLI 156 Query: 185 KK 186 +K Sbjct: 157 RK 158 >3RG9-A nrPDB Length = 240 Score = 160 bits (405), Expect = 3e-40, Method: Composition-based stats. Identities = 62/211 (29%), Positives = 98/211 (46%), Gaps = 33/211 (15%) Query: 2 VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTT------SSVEGKQNLVIMGR 55 +RP + +VA + GIG G +PW + + +YF+R+TT K+N V+MGR Sbjct: 26 LRPFSVVVASDEKGGIGDGGTIPWE-IPEDMQYFRRVTTNLRGKNVKPSPSKRNAVVMGR 84 Query: 56 KTWFSIPEKNRPLKDRINIVLSRELK---------------EPPRGAHFLAKSLDDALRL 100 KTW S+P K RPL +R+N+VLSR E + L+DALR+ Sbjct: 85 KTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGIPDPIKRAEAANDVVAVNGGLEDALRM 144 Query: 101 IEQPELASKVDMVWIVGGSSVYQEAMNQPGH---LRLFVTRI-MQEFESDTFFPEIDLGK 156 + E S ++ V+ +GG ++Y++A+ P + T + FF +I Sbjct: 145 LVSKEHTSSIETVFCIGGGTIYKQALCAPCVNVLQAIHRTVVRPASNSCSVFF-DIPAAG 203 Query: 157 YKLLPEYPGVLSEVQEEK------GIKYKFE 181 K V + +E+ G KY+FE Sbjct: 204 TKTPEGLELVRESITDERVSTGAGGKKYQFE 234 >6E4E-A nrPDB Length = 182 Score = 160 bits (405), Expect = 3e-40, Method: Composition-based stats. Identities = 47/182 (25%), Positives = 87/182 (47%), Gaps = 26/182 (14%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L+ +VA IG LPW L N+ K+ ++++T ++MGRKT+ SI Sbjct: 26 LSILVAHDLQRVIGFENQLPWH-LPNDLKHVKKLSTGH-------TLVMGRKTFESI--- 74 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 +PL +R N+VL+ + G + S++D +L V+I GG ++++E Sbjct: 75 GKPLPNRRNVVLTSDTSFNVEGVDVI-HSIEDIYQLPGH---------VFIFGGQTLFEE 124 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYE 184 +++ +++T I +F DTFFP +++ G ++ E+ I + F Sbjct: 125 MIDK--VDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEG---KLDEKNTIPHTFLHLI 179 Query: 185 KK 186 +K Sbjct: 180 RK 181 >4M2X-A nrPDB Length = 162 Score = 159 bits (403), Expect = 5e-40, Method: Composition-based stats. Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 30/185 (16%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + I A + + IG+ GD+PW L + +F+ +T ++MGR+TW S+P K Sbjct: 5 VGLIWAQATSGVIGRGGDIPWR-LPEDQAHFREITMGH-------TIVMGRRTWDSLPAK 56 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 RPL R N+VLSR+ GA + SL++AL E W++GG VY Sbjct: 57 VRPLPGRRNVVLSRQADFMASGAEVV-GSLEEALTSPET----------WVIGGGQVY-- 103 Query: 125 AMNQPGHLRLFVTRIM---QEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFE 181 A+ P R VT + D P +D E+ G++Y+ Sbjct: 104 ALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWR------FSRSGLRYRLY 157 Query: 182 VYEKK 186 Y + Sbjct: 158 SYHRS 162 >1IA3-A nrPDB Length = 192 Score = 158 bits (400), Expect = 1e-39, Method: Composition-based stats. Identities = 64/199 (32%), Positives = 99/199 (49%), Gaps = 20/199 (10%) Query: 1 MVRPLN--CIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTW 58 M++P + A+ +GIG G +PW LR E +YF+ +TT ++ +N VIMGRKTW Sbjct: 1 MLKPNVAIIVAALKPALGIGYKGKMPWR-LRKEIRYFKDVTTRTTKPNTRNAVIMGRKTW 59 Query: 59 FSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGG 118 SIP+K RPL DR+NI+LSR + + + S + L S V+ V+I+GG Sbjct: 60 ESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHAS-----SIESSLNLVSDVERVFIIGG 114 Query: 119 SSVYQEAMNQPGHLRLFVTRIMQ----EFESDTFFPEIDLGKYKLLPEYP-------GVL 167 + +Y E +N L +T I E DTF + L + P+ VL Sbjct: 115 AEIYNELINNSLVSHLLITEIEHPSPESIEMDTFL-KFPLESWTKQPKSELQKFVGDTVL 173 Query: 168 SEVQEEKGIKYKFEVYEKK 186 + +E Y + ++ +K Sbjct: 174 EDDIKEGDFTYNYTLWTRK 192 >6CXM-A nrPDB Length = 164 Score = 156 bits (394), Expect = 6e-39, Method: Composition-based stats. Identities = 46/185 (24%), Positives = 75/185 (40%), Gaps = 33/185 (17%) Query: 4 PLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPE 63 + I A S + IG++ +PW L + F+ MT V+MGR TW S+P Sbjct: 10 SMRLIWAQSTSGIIGRDNSIPWR-LPEDLARFKEMTMGHP-------VVMGRLTWESLPA 61 Query: 64 KNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQ 123 RPL R NIV++R+ GA + D+ W++GG+ +Y Sbjct: 62 SVRPLPGRRNIVVTRDADYRAEGAEVVTDLPDE--------------PDAWVIGGAQIYA 107 Query: 124 EAMNQPGHLRLFVTRIM---QEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKF 180 A+ + R VT + + D P +D E+ S G++++F Sbjct: 108 MALAR--ADRCEVTEVDIALTPLDGDARAPVLDDSWVATTGEWQTSTS------GLRFRF 159 Query: 181 EVYEK 185 Y + Sbjct: 160 CSYRR 164 >3EEM-A nrPDB Length = 227 Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats. Identities = 56/153 (36%), Positives = 88/153 (57%), Gaps = 9/153 (5%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 + + A+ MGIG G+LPW L E KYF+ +TT ++ KQN+VIMGRKTW SIP+K Sbjct: 7 VGIVAALLPEMGIGFQGNLPWR-LAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQK 65 Query: 65 NRPLKDRINIVLSRELK---EPPRGAHFLAKSLDDALRLIE-QPELASKVDMVWIVGGSS 120 RPL RIN+V+SR + + SL + L ++ +K++ ++I+GG Sbjct: 66 FRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGE 125 Query: 121 VYQEAMNQPGHLRLFVTRIMQEFESDTFFPEID 153 +Y+++M+ +T+IM E T P++D Sbjct: 126 IYRQSMD--LADHWLITKIMPLPE--TTIPQMD 154 >2W3W-A nrPDB Length = 167 Score = 154 bits (388), Expect = 3e-38, Method: Composition-based stats. Identities = 55/189 (29%), Positives = 84/189 (44%), Gaps = 27/189 (14%) Query: 1 MVRP-LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWF 59 M R + + A S + IG+ GD+PW + + F+ +T VIMGR+TW Sbjct: 1 MTRAEVGLVWAQSTSGVIGRGGDIPWS-VPEDLTRFKEVTMGH-------TVIMGRRTWE 52 Query: 60 SIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGS 119 S+P K RPL R N+V+SR GA +A SL+ AL A W++GG+ Sbjct: 53 SLPAKVRPLPGRRNVVVSRRPDFVAEGA-RVAGSLEAALA------YAGSDPAPWVIGGA 105 Query: 120 SVYQEAMNQPGHLRLFVTRIM---QEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGI 176 +Y + P R VT I + + D P +D E+ + G+ Sbjct: 106 QIY--LLALPHATRCEVTEIEIDLRRDDDDALAPALDDSWVGETGEW------LASRSGL 157 Query: 177 KYKFEVYEK 185 +Y+F Y + Sbjct: 158 RYRFHSYRR 166 >3IX9-A nrPDB Length = 190 Score = 150 bits (378), Expect = 4e-37, Method: Composition-based stats. Identities = 47/188 (25%), Positives = 82/188 (43%), Gaps = 25/188 (13%) Query: 1 MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS 60 M + + I A + IGK+ LPW L E ++F+ T ++MGR T+ Sbjct: 21 MTKKIVAIWAQDEEGVIGKDNRLPWY-LPAELQHFKETTLNH-------AILMGRVTFDG 72 Query: 61 IPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSS 120 + R L R ++L+R +E G + D +++ +++ ++IVGG Sbjct: 73 MGR--RLLPKRETLILTRNPEEKIDGV----ATFHDVQSVLDW--YSAQEKNLYIVGGKQ 124 Query: 121 VYQEAMNQPGHLRLFVTRIMQEFESDTFFP-EIDLGKYKLLPEYPGVLSEVQEEKGIKYK 179 ++Q +P + VT I E DT+FP E DL ++ + E+ Y Sbjct: 125 IFQAF--EPYLDEVIVTHIHARVEGDTYFPAEFDLSLFETVS---SKFYTKDEKNP--YD 177 Query: 180 FEV-YEKK 186 F + Y K+ Sbjct: 178 FTIQYRKR 185 >2JYB-A nrPDB Length = 162 Score = 147 bits (372), Expect = 2e-36, Method: Composition-based stats. Identities = 41/158 (25%), Positives = 84/158 (53%), Gaps = 16/158 (10%) Query: 5 LNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64 L + A+++N IG++G+LPWP + + K ++ + V++GR T+ S+ + Sbjct: 3 LVSVAALAENRVIGRDGELPWPSIPADKKQYRSRVA-------DDPVVLGRTTFESMRDD 55 Query: 65 NRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQE 124 L IV+SR + A S+++A+ + + + +++GG+++Y Sbjct: 56 ---LPGSAQIVMSRSERSFSVDTAHRAASVEEAVDIAASLD----AETAYVIGGAAIY-- 106 Query: 125 AMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPE 162 A+ QP R+ ++R+ E+E DT++PE D +++L E Sbjct: 107 ALFQPHLDRMVLSRVPGEYEGDTYYPEWDAAEWELDAE 144 >2L28-A nrPDB Length = 162 Score = 135 bits (341), Expect = 9e-33, Method: Composition-based stats. Identities = 42/179 (23%), Positives = 79/179 (44%), Gaps = 21/179 (11%) Query: 8 IVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRP 67 + A ++ IGK+G LPW L ++ YF+ T ++++GR+T+ S P+ RP Sbjct: 4 LWAQDRDGLIGKDGHLPWH-LPDDLHYFRAQTVGK-------IMVVGRRTYESFPK--RP 53 Query: 68 LKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMN 127 L +R N+VL+ + +GA + + P+ + I GG+ ++ + Sbjct: 54 LPERTNVVLTHQEDYQAQGAVVVHDVAAVFAYAKQHPD-----QELVIAGGAQIFTAFKD 108 Query: 128 QPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYEKK 186 L VTR+ FE DT ++ + + + + +EV++KK Sbjct: 109 --DVDTLLVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVE----DTNPALTHTYEVWQKK 161 >5ECC-A nrPDB Length = 157 Score = 129 bits (325), Expect = 5e-31, Method: Composition-based stats. Identities = 46/182 (25%), Positives = 80/182 (43%), Gaps = 27/182 (14%) Query: 4 PLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPE 63 L+ +VA+S+N IG D+PW + E F+ +T +++GRKT+ S+ Sbjct: 2 KLSLMVAISKNGVIGNGPDIPWSA-KGEQLLFKAIT-------YNQWLLVGRKTFESMGA 53 Query: 64 KNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQ 123 L +R V++R + S+ DAL L D V + GG +Y+ Sbjct: 54 ----LPNRKYAVVTRSSFTSDNENVLIFPSIKDALT-----NLKKITDHVIVSGGGEIYK 104 Query: 124 EAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVY 183 ++Q L ++ I E E D +FPEI + V ++ I Y ++++ Sbjct: 105 SLIDQ--VDTLHISTIDIEPEGDVYFPEIP-------SNFRPVFTQDFASN-INYSYQIW 154 Query: 184 EK 185 +K Sbjct: 155 QK 156 >5DXV-A nrPDB Length = 156 Score = 119 bits (299), Expect = 6e-28, Method: Composition-based stats. Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 38/162 (23%) Query: 4 PLNCIVAVSQNMGIGKNGDLP------WPPL-----------RNEFKYFQRMTTTSSVEG 46 ++ I A++ + IG + P W + + +F+R T Sbjct: 2 AISLIAALAVDRVIG-DTHFPDYEPDDWESVFSEFHDADAQNPADLAWFKRNTLDKP--- 57 Query: 47 KQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPEL 106 VIMGR TW SI RPL R NI+LS + R KS+D+A+ Sbjct: 58 ----VIMGRHTWESI---GRPLPGRKNIILSSQPGTDDR--VTWVKSVDEAIAA------ 102 Query: 107 ASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTF 148 V + ++GG VY++ + P +L++T I E S F Sbjct: 103 CGDVPEIMVIGGGRVYEQFL--PKAQKLYLTHIDAEGHSYCF 142 Score = 29.3 bits (64), Expect = 0.92, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 12/31 (38%), Gaps = 6/31 (19%) Query: 145 SDTFFPEIDLGKYKLLPEYPGVLSEVQEEKG 175 DT FP+ + ++ V SE + Sbjct: 16 GDTHFPDYEPDDWE------SVFSEFHDADA 40 >1CZ3-A nrPDB Length = 168 Score = 89.0 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 68/158 (43%), Gaps = 28/158 (17%) Query: 4 PLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPE 63 + ++A+ + I + + W + K F+++TT V+MGR T+ I Sbjct: 2 KVIFVLAMDVSGKIASSVE-SWSSF-EDRKNFRKITTEIGN------VVMGRITFEEI-- 51 Query: 64 KNRPLKDRINIVLSRELKEPPR-GAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVY 122 RPL +R+N+VL+R K F S D ++ +E + V ++GG +V+ Sbjct: 52 -GRPLPERLNVVLTRRPKTSNNPSLVFFNGSPADVVKFLE----GKGYERVAVIGGKTVF 106 Query: 123 QEAMNQPGHLRLFVTR----------IMQEFESDTFFP 150 E + + LFVT EFE +FP Sbjct: 107 TEFLREKLVDELFVTVEPYVFGKGIPFFDEFEG--YFP 142 >1JUV-A nrPDB Length = 193 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 69/184 (37%), Gaps = 35/184 (19%) Query: 18 GKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIV-- 75 G LPW ++ + + F+ T + ++IMG KT+ S+P L R +IV Sbjct: 23 GLGDGLPWGRVKKDLQNFKARTEGT-------IMIMGAKTFQSLPTL---LPGRSHIVVC 72 Query: 76 -LSRE-LKEPPRGAHFLAKSLDDALRLIEQPELASKVDM------------VWIVGGSSV 121 L+R+ + + + I E+ V ++GG ++ Sbjct: 73 DLARDYPVTKDGDLAHFYITWEQYITYISGGEIQVSSPNAPFETMLDQNSKVSVIGGPAL 132 Query: 122 YQEAMNQPGHLRLFVTRI------MQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKG 175 A+ P + V+RI + D F + D+ K +++ + + EV Sbjct: 133 LYAAL--PYADEVVVSRIVKRHRVNSTVQLDASFLD-DISKREMVETHWYKIDEVTTLTE 189 Query: 176 IKYK 179 YK Sbjct: 190 SVYK 193 >3JTW-A nrPDB Length = 178 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 11/145 (7%) Query: 1 MVRPLNCIVAVSQNMGIGKN-GDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWF 59 M R + +A+S + I + G + W L + + + K + VIMGR T+ Sbjct: 2 MARKVILFIAMSIDNYIADDQGAVDW--LEKNVHGTESDDSYEKMYSKIDTVIMGRTTYE 59 Query: 60 SIPEKNRPLK----DRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWI 115 + +K P K DR +++ L E + +S + ++ I++ + VWI Sbjct: 60 QVTQKLSPEKYVYADRQTYIVTSHLGEDTDKIKYWKQSPVELVKRIQKEKGKD----VWI 115 Query: 116 VGGSSVYQEAMNQPGHLRLFVTRIM 140 VGG+ + + +T + Sbjct: 116 VGGAKIIDPLVQANLIDTYILTTVP 140 >3KY8-A nrPDB Length = 197 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 54/144 (37%), Gaps = 25/144 (17%) Query: 7 CIVAVSQNMGIGKN-GDLPW-PPLRN----EFKYFQRMTTTSSVEGKQNLVIMGRKT--- 57 +A S + I G L W + N + T ++ + + ++MGR T Sbjct: 24 VFIATSLDGYIADKRGKLDWLHSVPNPNNVD-------TGFVALMERVDGLVMGRNTLDM 76 Query: 58 ---WFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVW 114 + ++P+ VLS + E P+G + L I A + ++ Sbjct: 77 VLSFDCDWPYSKPV-----FVLSNTMTEVPQGYEDKVFLVKGKLVDIIADLNAKGFNELY 131 Query: 115 IVGGSSVYQEAMNQPGHLRLFVTR 138 I GG ++ Q + + + +TR Sbjct: 132 IDGGVTI-QNFLKEDLIDEMVITR 154 >2XW7-A nrPDB Length = 178 Score = 35.0 bits (79), Expect = 0.022, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 33/88 (37%), Gaps = 1/88 (1%) Query: 50 LVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASK 109 +++MG T+ + E D+ VL+ + S D A E A Sbjct: 50 VLVMGASTYEWVVEHGDWSYDQPAWVLTHRPEIAAESHPMQVFSGDVAELHPELVAAAGG 109 Query: 110 VDMVWIVGGSSVYQEAMNQPGHLRLFVT 137 D VW+VGG V + + + V+ Sbjct: 110 KD-VWVVGGGDVAAQFVAADLIDEIIVS 136 >2P4G-A nrPDB Length = 270 Score = 32.7 bits (73), Expect = 0.100, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 33/84 (39%), Gaps = 4/84 (4%) Query: 88 HFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDT 147 +A + + L++ A ++ + I GG SVY++A++ RL +T I Sbjct: 166 VIVAPTSTNPLKIAFDALHARRLKKISIEGGPSVYRQALSLGIVDRLHLT-IAPNIICPV 224 Query: 148 ---FFPEIDLGKYKLLPEYPGVLS 168 F +I + + S Sbjct: 225 ESPLFGKISDDSFTTRLVLEMLSS 248 >2HXV-A nrPDB Length = 360 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 2/70 (2%) Query: 75 VLSRELKEPPRGAHFLAKSLDDA-LRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHL- 132 V+ E + K+L D + I + +D V + GGS V+ E ++ + Sbjct: 251 VIVFTESEEAEYPPHVEKALSDCSVESILRNLYERDIDSVLVEGGSKVFSEFLDHADVVF 310 Query: 133 RLFVTRIMQE 142 + T+I + Sbjct: 311 GFYSTKIFGK 320 >4HA7-A nrPDB Length = 249 Score = 30.4 bits (67), Expect = 0.50, Method: Composition-based stats. Identities = 16/117 (13%), Positives = 44/117 (37%), Gaps = 18/117 (15%) Query: 61 IPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDM------VW 114 I + +P +V++ E + + ++D +L++ +L + V Sbjct: 128 IKRQGKP----PIVVVTSEPIIKEQHVDYAICPINDTTKLVDWKKLFEILKEEFNIRSVM 183 Query: 115 IVGGSSVYQEAMNQPGHLRLFVTRIMQEFES----DTFFPEI----DLGKYKLLPEY 163 + GG++V + + + + + I F + P+ D+ +K + + Sbjct: 184 VEGGANVINQLLLRSDIVNSLIITIGSTFLGSSGTEVSPPQTVNLKDMSWWKGITDV 240 >4J1O-A nrPDB Length = 391 Score = 30.0 bits (66), Expect = 0.61, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 25/66 (37%), Gaps = 8/66 (12%) Query: 55 RKTWFSIP--------EKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPEL 106 RK W I + NR L R + LSRE E P +L++ + + + Sbjct: 200 RKVWERIRGTGTRLAVDGNRSLPSRDALRLSRECPEIPFVLEQPCNTLEEIAAIRGRVQH 259 Query: 107 ASKVDM 112 +D Sbjct: 260 GIYLDE 265 >6BKF-A nrPDB Length = 621 Score = 29.6 bits (65), Expect = 0.77, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 16/41 (39%) Query: 55 RKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLD 95 RK + + P+ RI IV + L +++D Sbjct: 384 RKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAID 424 >3FZA-A nrPDB Length = 112 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 29/74 (39%), Gaps = 7/74 (9%) Query: 48 QNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELA 107 +N V++ KTW S + + L R+N+ L +++E+ Sbjct: 17 ENPVVVYSKTWCSYSSEVKSLFKRLNV------DPLVVELDELGAQGPQIQKVLERLTGQ 70 Query: 108 SKVDMVWIVGGSSV 121 V V+I GG + Sbjct: 71 HTVPNVFI-GGKHI 83 >3POC-A nrPDB Length = 666 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 30/78 (38%), Gaps = 7/78 (8%) Query: 77 SRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLF- 135 + K P F+ + D LRLI + KV+ G VY+E + + Sbjct: 211 TVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEK-----GYEVYEEGVKNNYFCKRED 265 Query: 136 -VTRIMQEFESDTFFPEI 152 + + DT FP++ Sbjct: 266 GSDFVAAVWPGDTHFPDM 283 >2AEG-A nrPDB Length = 268 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 12/26 (46%) Query: 55 RKTWFSIPEKNRPLKDRINIVLSREL 80 R W RPL + I+LSRE Sbjct: 213 RAPWDEAKHLARPLPNDALIILSREP 238 >4K8U-A nrPDB Length = 198 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 122 YQEAMNQPGHLRLFVTRIMQEFES--------DTFFPEIDLGKYKLLPEYPGVLSEVQEE 173 + + P R+ + + Q +TF P+ + ++ + G L E Sbjct: 94 FDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLG 153 Query: 174 KGIKYKFEVYE 184 G KF ++ Sbjct: 154 FGYP-KFISHQ 163 >3H0M-B nrPDB Length = 478 Score = 27.3 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 45/124 (36%), Gaps = 10/124 (8%) Query: 71 RINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIV--GGSSVYQEAMNQ 128 R +I +S K + ++ R +++ + +V GG V + Sbjct: 193 RCDINVSIRPKGSKEFGTRVEIKNVNSFRFVQKALEYEIERQINVVEEGGEVVQETRTFD 252 Query: 129 PGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEY--------PGVLSEVQEEKGIKYKF 180 P + + R +E E +FP+ DL K+ E+ P + + E +Y Sbjct: 253 PQTGKTYPMRTKEEAEDYRYFPDPDLVPLKVKKEWIEEIKKNMPELPDQRFERLIKEYGL 312 Query: 181 EVYE 184 YE Sbjct: 313 SEYE 316 >1UP7-A nrPDB Length = 417 Score = 27.3 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 33/82 (40%), Gaps = 14/82 (17%) Query: 112 MVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPE--------- 162 + ++GG S Y + + RI + F +ID K K++ + Sbjct: 4 RIAVIGGGSSYTPELVKGLLDISEDVRIDE-----VIFYDIDEEKQKIVVDFVKRLVKDR 58 Query: 163 YPGVLSEVQEEKGIKYKFEVYE 184 + ++S+ E + K+ +++ Sbjct: 59 FKVLISDTFEGAVVDAKYVIFQ 80 >3T8I-A nrPDB Length = 306 Score = 27.3 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 54 GRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSL--DDALRLIEQPELASKVD 111 G W RP K+ + R KE LA S + AL ++ P + +V Sbjct: 83 GMSNWNYPEPNKRPEKEHAIDAILRLSKEHEGELEILAISPLTNIALAYLKDPSVVKRVK 142 Query: 112 MVWIVGGS 119 +WI+GG+ Sbjct: 143 KIWIMGGA 150 >5AMB-A nrPDB Length = 629 Score = 26.9 bits (58), Expect = 4.6, Method: Composition-based stats. Identities = 8/50 (16%), Positives = 23/50 (46%) Query: 53 MGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIE 102 M ++W +I + P D+ N+ ++ + + A + + ++ +E Sbjct: 256 MWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLE 305 >6AQE-A nrPDB Length = 266 Score = 26.6 bits (57), Expect = 6.7, Method: Composition-based stats. Identities = 3/19 (15%), Positives = 10/19 (52%) Query: 24 PWPPLRNEFKYFQRMTTTS 42 PW + + K+++ + + Sbjct: 222 PWYVVPADRKWYRDLVLSH 240 >1OJM-A nrPDB Length = 729 Score = 26.6 bits (57), Expect = 6.8, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 30/75 (40%), Gaps = 17/75 (22%) Query: 31 EFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFL 90 + ++F++ T NLV MGR V++ L++ + Sbjct: 162 DPEHFRKTTDNPFKALGGNLVDMGRVK-----------------VIAGLLRKDDQEISST 204 Query: 91 AKSLDDALRLIEQPE 105 +S++ +L++Q E Sbjct: 205 IRSIEQVFKLVDQGE 219 >3VNN-A nrPDB Length = 139 Score = 26.2 bits (56), Expect = 9.0, Method: Composition-based stats. Identities = 7/21 (33%), Positives = 10/21 (47%) Query: 55 RKTWFSIPEKNRPLKDRINIV 75 RK + + P+ RI IV Sbjct: 116 RKRYEILSSIFTPIPGRIEIV 136 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.134 0.387 Lambda K H 0.267 0.0415 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,246,751 Number of Sequences: 36641 Number of extensions: 269096 Number of successful extensions: 1238 Number of sequences better than 10.0: 57 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 962 Number of HSP's gapped (non-prelim): 111 length of query: 187 length of database: 10,336,785 effective HSP length: 91 effective length of query: 96 effective length of database: 7,002,454 effective search space: 672235584 effective search space used: 672235584 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 56 (26.2 bits)