BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00367 (558 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6DHM-A nrPDB 1085 0.0 1L1F-A nrPDB 1050 0.0 1B26-A nrPDB 319 2e-87 3AOE-A nrPDB 293 1e-79 1GTM-A nrPDB 282 2e-76 1EUZ-A nrPDB 275 4e-74 4XGI-A nrPDB 275 4e-74 1BVU-A nrPDB 272 3e-73 3K8Z-A nrPDB 260 1e-69 3K92-A nrPDB 254 9e-68 2YFQ-A nrPDB 232 3e-61 1V9L-A nrPDB 224 1e-58 3AOE-E nrPDB 202 3e-52 1HRD-A nrPDB 159 3e-39 3R3J-A nrPDB 151 6e-37 2YFH-A nrPDB 148 5e-36 5IJZ-A nrPDB 145 6e-35 2BMA-A nrPDB 132 4e-31 4FHN-X nrPDB 130 1e-30 5XW0-A nrPDB 107 1e-23 5B37-A nrPDB 81 1e-15 6ACF-A nrPDB 72 7e-13 3VPX-A nrPDB 69 4e-12 1BW9-B nrPDB 60 2e-09 1LEH-A nrPDB 54 2e-07 5JY4-B nrPDB 36 0.037 4W9U-A nrPDB 33 0.23 5LZ5-A nrPDB 31 1.4 3GNC-A nrPDB 31 1.4 3C98-B nrPDB 31 1.6 2QBO-A nrPDB 30 2.9 1OMO-A nrPDB 29 4.5 4R3U-C nrPDB 29 5.0 2PAJ-A nrPDB 29 5.9 >6DHM-A nrPDB Length = 582 Score = 1085 bits (2806), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/561 (95%), Positives = 542/561 (96%), Gaps = 3/561 (0%) Query: 1 MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQP---GLALAARRHYSEAV 57 MYR LGEALLLSR GPAALGS +ADSA LLG ARGQ AAA GL ARRHYSEA Sbjct: 22 MYRCLGEALLLSRIGPAALGSVAADSAVLLGRARGQAAAAVAAPQPGLVPPARRHYSEAA 81 Query: 58 ADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLS 117 ADREDDPNFFKMVEGFFDRGASIVEDKLVEDL+TRE+EEQKRNRVRGILRIIKPCNHVLS Sbjct: 82 ADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRGILRIIKPCNHVLS 141 Query: 118 LSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDV 177 LSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDV Sbjct: 142 LSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDV 201 Query: 178 PFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIA 237 PFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPG+DVPAPDMSTGEREMSWIA Sbjct: 202 PFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIA 261 Query: 238 DTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTP 297 DTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTP Sbjct: 262 DTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTP 321 Query: 298 GFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGS 357 GFGDKTF VQGFGNVGLHSMRYLHRFGAKC+AVGESDGSIWNPDGIDPKELEDFKLQHG+ Sbjct: 322 GFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFKLQHGT 381 Query: 358 ILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIF 417 ILGFPKAK YEGSILE DCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIF Sbjct: 382 ILGFPKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIF 441 Query: 418 LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERK 477 LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERK Sbjct: 442 LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERK 501 Query: 478 FGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA 537 FGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA Sbjct: 502 FGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA 561 Query: 538 AYVNAIEKVFKVYNEAGVTFT 558 AYVNAIEKVF+VYNEAGVTFT Sbjct: 562 AYVNAIEKVFRVYNEAGVTFT 582 >1L1F-A nrPDB Length = 505 Score = 1050 bits (2716), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 54 SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCN 113 SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCN Sbjct: 1 SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCN 60 Query: 114 HVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCA 173 HVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCA Sbjct: 61 HVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCA 120 Query: 174 VVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREM 233 VVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREM Sbjct: 121 VVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREM 180 Query: 234 SWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSIL 293 SWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSIL Sbjct: 181 SWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSIL 240 Query: 294 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL 353 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL Sbjct: 241 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL 300 Query: 354 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA 413 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA Sbjct: 301 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA 360 Query: 414 DKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQES 473 DKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQES Sbjct: 361 DKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQES 420 Query: 474 LERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLD 533 LERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLD Sbjct: 421 LERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLD 480 Query: 534 LRTAAYVNAIEKVFKVYNEAGVTFT 558 LRTAAYVNAIEKVFKVYNEAGVTFT Sbjct: 481 LRTAAYVNAIEKVFKVYNEAGVTFT 505 >1B26-A nrPDB Length = 416 Score = 319 bits (818), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 190/495 (38%), Positives = 272/495 (54%), Gaps = 85/495 (17%) Query: 63 DPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPI 122 + + ++M F+R AS++ DL + +E +R + VL + FP+ Sbjct: 3 EKSLYEMAVEQFNRAASLM------DLESDLAEVLRRPK------------RVLIVEFPV 44 Query: 123 RRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182 R DDG EV GYR QH+ R P KGGIRY DV++DEVKALA MT+K AV+++PFGG Sbjct: 45 RMDDGHVEVFTGYRVQHNVARGPAKGGIRYHPDVTLDEVKALAFWMTWKTAVMNLPFGGG 104 Query: 183 KAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYAS 242 K GV+++PK + NELE+++RRF E+ + IGP D+PAPD++T ++W DTY+ Sbjct: 105 KGGVRVDPKKLSRNELERLSRRFFSEI--QVIIGPYNDIPAPDVNTNADVIAWYMDTYSM 162 Query: 243 TIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDK 302 +GH VTGKP+ GG GR ATGRGV + M +LG+ P Sbjct: 163 NVGH---TVLGIVTGKPVELGGSKGREEATGRGV------KVCAGLAMDVLGIDP--KKA 211 Query: 303 TFVVQGFGNVG-LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGF 361 T VQGFGNVG ++ G+K +AV +S G I+NP+G D +EL +K +HG+++ + Sbjct: 212 TVAVQGFGNVGQFAALLISQELGSKVVAVSDSRGGIYNPEGFDVEELIRYKKEHGTVVTY 271 Query: 362 PKAKPYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420 PK + +LE D DIL+PAA E + NA R+KAK + EGANGPTTPEAD+I R Sbjct: 272 PKGERITNEELLELDVDILVPAALEGAIHAGNAERIKAKAVVEGANGPTTPEADEILSRR 331 Query: 421 NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK 480 I+V+PD+ NAGGVTVSYFEW+++L +F ++ D Sbjct: 332 GILVVPDILANAGGVTVSYFEWVQDLQ-------SFFWDLDQ------------------ 366 Query: 481 HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV 540 V + L M+ + +M+ KYN +D+RTAAY+ Sbjct: 367 -------------------------VRNALEKMMKGAFNDVMKVKEKYN--VDMRTAAYI 399 Query: 541 NAIEKVFKVYNEAGV 555 AI++V + G+ Sbjct: 400 LAIDRVAYATKKRGI 414 >3AOE-A nrPDB Length = 424 Score = 293 bits (751), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 161/368 (43%), Positives = 227/368 (61%), Gaps = 20/368 (5%) Query: 109 IKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLM 168 +K VL + P+R DDGS EGYR H+ R P KGG+RY +V++ EV ALA M Sbjct: 40 LKRPKRVLIVDVPVRLDDGSVAYFEGYRVHHNTARGPAKGGVRYHPEVTLSEVMALAGWM 99 Query: 169 TYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMST 228 T K A V +P+GG K G++++P+ + ELE++TRR+T E+ +GP D+PAPD++T Sbjct: 100 TIKNAAVGLPYGGGKGGIRVDPRKLSPGELERLTRRYTSEIGI--LLGPDRDIPAPDVNT 157 Query: 229 GEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEAS 288 GEREM+W+ DTY+ +G VTGKPI+ GG GR ATGRGVF I A+ Sbjct: 158 GEREMAWMMDTYSMNVGR---TVPGVVTGKPIALGGSLGRRDATGRGVF------ITAAA 208 Query: 289 YMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKEL 348 +G+ +QGFGNVG + R H GA+ +AV + G+++N GIDP +L Sbjct: 209 AAEKIGLQ--VEGARVAIQGFGNVGNAAARAFHDHGARVVAVQDHTGTVYNEAGIDPYDL 266 Query: 349 EDFKLQHGSILGFPKAKPYEGS-ILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANG 407 + G + G+PKA+P + + L+PAA EKQ+T+ NA R++A+I+AEGANG Sbjct: 267 LRHVQEFGGVRGYPKAEPLPAADFWGLPVEFLVPAALEKQITEQNAWRIRARIVAEGANG 326 Query: 408 PTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLL 467 PTTP AD I LE+ ++V+PD+ NAGGVTVSYFEW+++ N SY F E + N L Sbjct: 327 PTTPAADDILLEKGVLVVPDVIANAGGVTVSYFEWVQDFN--SY----FWTEEEINARLE 380 Query: 468 MSVQESLE 475 ++ + E Sbjct: 381 RVLRNAFE 388 >1GTM-A nrPDB Length = 419 Score = 282 bits (722), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 159/411 (38%), Positives = 230/411 (55%), Gaps = 37/411 (9%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 L +K ++ ++ P+ DDGS +V G+R QH+ R P KGGIR+ + ++ VKALA Sbjct: 27 LEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQHNWARGPTKGGIRWHPEETLSTVKALA 86 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 + MT+K AV+D+P+GG K G+ ++PK +D E E++ R + + I P D+PAPD Sbjct: 87 AWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAIYD--VISPYEDIPAPD 144 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIN 285 + T + M+W+ D Y TI A +TGKP+S GG GRI AT RG + I Sbjct: 145 VYTNPQIMAWMMDEY-ETISRRKTPAFGIITGKPLSIGGSLGRIEATARGASYTIREAAK 203 Query: 286 EASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHR-FGAKCIAVGESDGSIWNPDGID 344 + ++ G KT +QG+GN G + + + FG K +AV +S G I+NPDG++ Sbjct: 204 VLGWDTLKG-------KTIAIQGYGNAGYYLAKIMSEDFGMKVVAVSDSKGGIYNPDGLN 256 Query: 345 PKELEDFKLQHGSILGFPKAKPYEGS-ILEADCDILIPAASEKQLTKSNAPRVKAKIIAE 403 E+ +K +HGS+ FP A +LE + D+L PAA E+ +TK NA +KAKI+AE Sbjct: 257 ADEVLKWKNEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIKAKIVAE 316 Query: 404 GANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSN 463 ANGP TPEAD+I E+ I+ IPD NAGGVTVSYFEW++N+ Sbjct: 317 VANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNIT--------------GY 362 Query: 464 YHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTM 514 Y + V+E L++K T F D + A EK+I AY + Sbjct: 363 YWTIEEVRERLDKKM-----------TKAFYDVYNIAKEKNIHMRDAAYVV 402 >1EUZ-A nrPDB Length = 419 Score = 275 bits (703), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 151/344 (43%), Positives = 208/344 (60%), Gaps = 13/344 (3%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 L +K ++ +S PI DDGS +V G+R QH+ R P KGGIR+ ++ VKALA Sbjct: 28 LEWLKKPMRIVEVSVPIEMDDGSVKVFTGFRVQHNWARGPTKGGIRWHPAETLSTVKALA 87 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 + MT+K AVVD+P+GG K G+ +NPK ++ E E++ R + A IGP D+PAPD Sbjct: 88 TWMTWKVAVVDLPYGGGKGGIIVNPKELSEREQERLARAYIR--AVYDVIGPWTDIPAPD 145 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIN 285 + T + M W+ D Y TI A +TGKP+S GG GR +AT +G I Sbjct: 146 VYTNPKIMGWMMDEY-ETIMRRKGPAFGVITGKPLSIGGSLGRGTATAQGAIF----TIR 200 Query: 286 EASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYL-HRFGAKCIAVGESDGSIWNPDGID 344 EA+ LG+ K VQG+GN G ++ + + G +AV +S G I+NPDG+D Sbjct: 201 EAA--KALGID--LKGKKIAVQGYGNAGYYTAKLAKEQLGMTVVAVSDSRGGIYNPDGLD 256 Query: 345 PKELEDFKLQHGSILGFPKAKPYEGS-ILEADCDILIPAASEKQLTKSNAPRVKAKIIAE 403 P E+ +K +HGS+ FP A +LE + D+L PAA E+ +T+ NA +KAKI+AE Sbjct: 257 PDEVLKWKREHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITEKNADNIKAKIVAE 316 Query: 404 GANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLN 447 ANGP TPEAD I E+ I+ IPD NAGGVTVSYFEW++N+N Sbjct: 317 VANGPVTPEADDILREKGILQIPDFLCNAGGVTVSYFEWVQNIN 360 >4XGI-A nrPDB Length = 436 Score = 275 bits (702), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 154/371 (41%), Positives = 216/371 (58%), Gaps = 22/371 (5%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 + +K +L + PI D+G+ EGYR QH+ R P KGG+RY DV++ EV AL+ Sbjct: 49 IETLKRPKRILIVDVPIELDNGTVAHFEGYRVQHNVSRGPGKGGVRYHQDVTLSEVMALS 108 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 + M+ K A V+VP+GGAK G++++P+ + ELE++TRR+T E+ IGP D+PAPD Sbjct: 109 AWMSVKNAAVNVPYGGAKGGIRVDPRKLSRGELERVTRRYTSEIGI--IIGPNTDIPAPD 166 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVF-HGIENFI 284 ++T E+ M+W+ DTY+ G A VTGKPIS GG GR ATGRGVF G E Sbjct: 167 VNTNEQIMAWMMDTYSMNQGQ---TATGVVTGKPISLGGSLGRKEATGRGVFVVGCEAAK 223 Query: 285 NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGID 344 + + VQGFGNVG + + GAK IAV + G+I P G+D Sbjct: 224 KKGVEIE---------GARIAVQGFGNVGGIAAKLFQEAGAKVIAVQDHTGTIHQPAGVD 274 Query: 345 PKELEDFKLQHGSILGFPKAKPY-EGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAE 403 +L D + G + GF A+P + +ILIPAA E Q+T+ NA +++ KII E Sbjct: 275 TAKLLDHVGRTGGVAGFEGAEPMPNDEFWTVETEILIPAALENQITEKNASKIRTKIIVE 334 Query: 404 GANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSN 463 GANGPTT AD I ++VIPD+ NAGGVTVSYFEW+++ + F E + N Sbjct: 335 GANGPTTTAADDILSANGVLVIPDVIANAGGVTVSYFEWVQDFSSF------FWTEDEIN 388 Query: 464 YHLLMSVQESL 474 + L ++E+ Sbjct: 389 HRLERVMREAF 399 >1BVU-A nrPDB Length = 418 Score = 272 bits (696), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 162/451 (35%), Positives = 241/451 (53%), Gaps = 65/451 (14%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 L +K ++ +S P+ DDGS +V G+R Q++ R P KGGIR+ + ++ VKALA Sbjct: 27 LEFLKRPQRIVEVSIPVEMDDGSVKVFTGFRVQYNWARGPTKGGIRWHPEETLSTVKALA 86 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 + MT+K AV+D+P+GG K GV NPK +D E E++ R + + I P D+PAPD Sbjct: 87 AWMTWKTAVMDLPYGGGKGGVICNPKEMSDREKERLARGYVRAIYD--VISPYTDIPAPD 144 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIN 285 + T + M+W+ D Y TI + +TGKP S GGI R+ AT RG + + Sbjct: 145 VYTNPQIMAWMMDEY-ETISRRKDPSFGVITGKPPSVGGIVARMDATARGASYTV----R 199 Query: 286 EASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYL-HRFGAKCIAVGESDGSIWNPDGID 344 EA+ LGM KT +QG+GN G + + + +G K +AV ++ G I+NPDG++ Sbjct: 200 EAA--KALGMD--LKGKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVSDTKGGIYNPDGLN 255 Query: 345 PKELEDFKLQHGSILGFPKAKPYEGS-ILEADCDILIPAASEKQLTKSNAPRVKAKIIAE 403 E+ +K + GS+ FP A +LE + D+L P+A E+ +TK NA +KAKI+AE Sbjct: 256 ADEVLAWKKKTGSVKDFPGATNITNEELLELEVDVLAPSAIEEVITKKNADNIKAKIVAE 315 Query: 404 GANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSN 463 ANGPTTPEAD+I E+ I++IPD NAGGVTVSYFEW++N+ + Sbjct: 316 LANGPTTPEADEILYEKGILIIPDFLCNAGGVTVSYFEWVQNIT--------------GD 361 Query: 464 YHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMR 523 Y + + L++K T F D + EK+I Sbjct: 362 YWTVEETRAKLDKKM-----------TKAFWDVYNTHKEKNI------------------ 392 Query: 524 TAMKYNLGLDLRTAAYVNAIEKVFKVYNEAG 554 ++R AAYV A+ +V++ + G Sbjct: 393 ---------NMRDAAYVVAVSRVYQAMKDRG 414 >3K8Z-A nrPDB Length = 423 Score = 260 bits (664), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 135/341 (39%), Positives = 211/341 (61%), Gaps = 14/341 (4%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 + ++K +L++ P+R DDGS ++ GYRA H+ P KGGIR+ +V+ EVKAL Sbjct: 38 VYELLKEPMRLLTVKIPVRMDDGSVKIFTGYRA-HNDSVGPTKGGIRFHPNVTEKEVKAL 96 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 + M+ KC ++D+P+GG K G+ +P++ + ELE+++R + +++ +GP DVPAP Sbjct: 97 SIWMSLKCGIIDLPYGGGKGGIVCDPRDMSFRELERLSRGYVRAISQ--IVGPTKDVPAP 154 Query: 225 DMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFI 284 D+ T + M+W+ D Y S I + N+ +TGKP+ GG HGR SAT +GV I+ Sbjct: 155 DVFTNSQIMAWMMDEY-SRIDEF--NSPGFITGKPLVLGGSHGRESATAKGVTICIKEAA 211 Query: 285 NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGID 344 + + I G VVQGFGN G + +++H GAK + + ++ G +++P+G+D Sbjct: 212 KKRG-IDIKG-------ARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLD 263 Query: 345 PKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEG 404 L D + G++ +LE DCDIL+PAA E Q+T+ NA ++AKI+ E Sbjct: 264 IDYLLDRRDSFGTVTKLFNDTITNQELLELDCDILVPAAIENQITEENAHNIRAKIVVEA 323 Query: 405 ANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKN 445 ANGPTT E KI +R+I+++PD+ +AGGVTVSYFEW++N Sbjct: 324 ANGPTTLEGTKILSDRDILLVPDVLASAGGVTVSYFEWVQN 364 >3K92-A nrPDB Length = 424 Score = 254 bits (648), Expect = 9e-68, Method: Compositional matrix adjust. Identities = 126/338 (37%), Positives = 204/338 (60%), Gaps = 13/338 (3%) Query: 108 IIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASL 167 ++K +L++ P++ D+GS +V GYR+QH+ P KGG+R+ +V+ ++VKAL+ Sbjct: 41 LMKEPQRMLTVRIPVKMDNGSVKVFTGYRSQHNDAVGPTKGGVRFHPEVNEEKVKALSIW 100 Query: 168 MTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMS 227 MT KC + ++P+GG K G+ +P+ + ELE+++R + +++ +GP D+PAPD+ Sbjct: 101 MTLKCGIANLPYGGGKGGIICDPRTMSFGELERLSRGYVRAISQ--IVGPTKDIPAPDVY 158 Query: 228 TGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEA 287 T + M+W+ D Y S + +D + +TGKP+ GG GR +AT +GV IE + + Sbjct: 159 TNSQIMAWMMDEY-SRLREFD--SPGFITGKPLVLGGSQGRETATAQGVTICIEEAVKKK 215 Query: 288 SYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKE 347 + ++QGFGN G +++H GAK I + +++G ++NPDG+D Sbjct: 216 GIK--------LQNARIIIQGFGNAGSFLAKFMHDAGAKVIGISDANGGLYNPDGLDIPY 267 Query: 348 LEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANG 407 L D + G + +LE DCDIL+PAA Q+T NA ++A I+ E ANG Sbjct: 268 LLDKRDSFGMVTNLFTDVITNEELLEKDCDILVPAAISNQITAKNAHNIQASIVVERANG 327 Query: 408 PTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKN 445 PTT +A KI ER ++++PD+ +AGGVTVSYFEW++N Sbjct: 328 PTTIDATKILNERGVLLVPDILASAGGVTVSYFEWVQN 365 >2YFQ-A nrPDB Length = 421 Score = 232 bits (592), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 132/348 (37%), Positives = 206/348 (59%), Gaps = 20/348 (5%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 + ++K V+ +S P++ DDG+ +V +G+R+ HS P KGG+R+ +V++DEVKAL Sbjct: 28 VYELLKEPQRVIEISIPVKMDDGTVKVFKGWRSAHSSAVGPSKGGVRFHPNVNMDEVKAL 87 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 + MT+K + +P+GG K G+ ++P ++ ELE+++R + L K ++G ID+PAP Sbjct: 88 SLWMTFKGGALGLPYGGGKGGICVDPAELSERELEQLSRGWVRGLYK--YLGDRIDIPAP 145 Query: 225 DMSTGEREMSWIADTYASTIGH-YDINAHACVTGKPISQGGIHGRISATGRGVFHGIENF 283 D++T + MSW D Y G DI TGKP++ GG GR ATG G+ Sbjct: 146 DVNTNGQIMSWFVDEYVKLNGERMDIGTF---TGKPVAFGGSEGRNEATG----FGVAVV 198 Query: 284 INEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDG-----SIW 338 + E++ + M D VQGFGNVG +++ + R G K A+ E D +++ Sbjct: 199 VRESAKRFGIKME----DAKIAVQGFGNVGTFTVKNIERQGGKVCAIAEWDRNEGNYALY 254 Query: 339 NPDGIDPKELEDFKLQHGSILGFPKA-KPYEGSILEADCDILIPAASEKQLTKSNAPRVK 397 N +GID KEL +K + +++GFP A + + + DI++PAA E +T A + Sbjct: 255 NENGIDFKELLAYKEANKTLIGFPGAERITDEEFWTKEYDIIVPAALENVITGERAKTIN 314 Query: 398 AKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKN 445 AK++ E ANGPTTPE DK+ ER I + PD+ N+GGV VSY+EW++N Sbjct: 315 AKLVCEAANGPTTPEGDKVLTERGINLTPDILTNSGGVLVSYYEWVQN 362 >1V9L-A nrPDB Length = 421 Score = 224 bits (570), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 129/348 (37%), Positives = 193/348 (55%), Gaps = 20/348 (5%) Query: 107 RIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALAS 166 +I+ VL ++ P+R D G +EV EGYR QH P KGG+R+ +V++ + ALA Sbjct: 29 KILSRPRRVLIVNIPVRLDGGGFEVFEGYRVQHCDVLGPYKGGVRFHPEVTLADDVALAI 88 Query: 167 LMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDM 226 LMT K ++ +P+GGAK V+++PK + ELE+++R + +A IG +D+PAPD+ Sbjct: 89 LMTLKNSLAGLPYGGAKGAVRVDPKKLSQRELEELSRGYARAIAP--LIGDVVDIPAPDV 146 Query: 227 STGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINE 286 T + M+W+ D Y+ G+ N T KP G R ATG GV + Sbjct: 147 GTNAQIMAWMVDEYSKIKGY---NVPGVFTSKPPELWGNPVREYATGFGVAVATREMAKK 203 Query: 287 ASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPK 346 + G KT +QG GNVG + +L + GAK IAV + +G + +G++ + Sbjct: 204 --------LWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVAYRKEGLNVE 255 Query: 347 ELEDFKLQHGSILG--FPKAKPYE-----GSILEADCDILIPAASEKQLTKSNAPRVKAK 399 ++ K G L F E +I + D DI +PAA E + NA VKA+ Sbjct: 256 LIQKNKGLTGPALVELFTTKDNAEFVKNPDAIFKLDVDIFVPAAIENVIRGDNAGLVKAR 315 Query: 400 IIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLN 447 ++ EGANGPTTPEA++I ER ++V+PD+ NAGGV +SY EW++NL Sbjct: 316 LVVEGANGPTTPEAERILYERGVVVVPDILANAGGVIMSYLEWVENLQ 363 >3AOE-E nrPDB Length = 419 Score = 202 bits (514), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 117/335 (34%), Positives = 174/335 (51%), Gaps = 16/335 (4%) Query: 113 NHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKC 172 +++LS P+ DDG + +GYR H R P KGG+R V++ + LA+ MT K Sbjct: 43 KRLVTLSLPVVMDDGKVRIFQGYRVVHDIARGPAKGGVRLDPGVTLGQTAGLAAWMTLKA 102 Query: 173 AVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGERE 232 AV D+PFGGA G+ ++PK + ELE++ RR+T EL G IGP D+ PD+ ++ Sbjct: 103 AVYDLPFGGAAGGIAVDPKGLSPQELERLVRRYTAELV--GLIGPDSDILGPDLGADQQV 160 Query: 233 MSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSI 292 M+WI DTY+ T+G VTGKP + GG GR A G G +E + + Sbjct: 161 MAWIMDTYSMTVGS---TVPGVVTGKPHALGGSEGRDDAAGLGALLVLEALAKRRG-LDL 216 Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFK 352 G VVQG G VG + R G + +AV S G ++ P+G+D E+ Sbjct: 217 RG-------ARVVVQGLGQVGAAVALHAERLGMRVVAVATSMGGMYAPEGLDVAEVLSAY 269 Query: 353 LQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPE 412 GS+ P+ + + ++L+ AA E L A +V+A+ + E AN PE Sbjct: 270 EATGSL---PRLDLAPEEVFGLEAEVLVLAAREGALDGDRARQVQAQAVVEVANFGLNPE 326 Query: 413 ADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLN 447 A+ L + +V+PDL GG+ SY EW+++LN Sbjct: 327 AEAYLLGKGALVVPDLLSGGGGLLASYLEWVQDLN 361 >1HRD-A nrPDB Length = 449 Score = 159 bits (402), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 129/438 (29%), Positives = 206/438 (47%), Gaps = 55/438 (12%) Query: 51 RHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIK 110 R +E D+P F + VE +V+ E EE V + R++ Sbjct: 6 RVIAEVEKKYADEPEFVQTVEEVLSSLGPVVDAH-------PEYEE-----VALLERMVI 53 Query: 111 PCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTY 170 P V+ P D+G V GYR Q + P KGG+R++ V++ +K L + Sbjct: 54 P-ERVIEFRVPWEDDNGKVHVNTGYRVQFNGAIGPYKGGLRFAPSVNLSIMKFLGFEQAF 112 Query: 171 KCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGE 230 K ++ +P GGAK G +P +D E+ + + F EL + IGP IDVPA D+ G Sbjct: 113 KDSLTTLPMGGAKGGSDFDPNGKSDREVMRFCQAFMTELYRH--IGPDIDVPAGDLGVGA 170 Query: 231 REMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYM 290 RE+ ++ Y +G + + +TGK S GG R ATG G + +E + + Sbjct: 171 REIGYMYGQYRKIVGGF---YNGVLTGKARSFGGSLVRPEATGYGSVYYVEAVMKHEN-D 226 Query: 291 SILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKE--- 347 +++G KT + GFGNV + + L GAK + + DG I++P+GI +E Sbjct: 227 TLVG-------KTVALAGFGNVAWGAAKKLAELGAKAVTLSGPDGYIYDPEGITTEEKIN 279 Query: 348 ------------LEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPR 395 ++D+ + G + FP KP+ + DI++P A++ + A + Sbjct: 280 YMLEMRASGRNKVQDYADKFG-VQFFPGEKPWGQKV-----DIIMPCATQNDVDLEQAKK 333 Query: 396 VKA---KIIAEGANGPTTPEADKIFLER-NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSY 451 + A K E AN PTT EA + +++ N++V P +NAGGV VS FE +N +S+ Sbjct: 334 IVANNVKYYIEVANMPTTNEALRFLMQQPNMVVAPSKAVNAGGVLVSGFEMSQNSERLSW 393 Query: 452 GRLTFKYERDSNYHLLMS 469 E DS H +M+ Sbjct: 394 T----AEEVDSKLHQVMT 407 >3R3J-A nrPDB Length = 456 Score = 151 bits (382), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 108/361 (29%), Positives = 174/361 (48%), Gaps = 26/361 (7%) Query: 97 QKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDV 156 +K N G+L I V+ P D G ++ G+R Q++ P KGG+R+ V Sbjct: 49 KKDNVYIGVLENIAEPERVIQFRVPWINDKGEHKMNRGFRVQYNSVLGPYKGGLRFHPAV 108 Query: 157 SVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIG 216 ++ +K L +K ++ +P GG K G +PK ++NE+ K + F L + +IG Sbjct: 109 NLSVIKFLGFEQIFKNSLTTLPMGGGKGGSDFDPKGKSENEILKFCQSFMTNLFR--YIG 166 Query: 217 PGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGV 276 P DVPA D+ G RE+ ++ Y ++ +TGK I GG + R ATG GV Sbjct: 167 PNTDVPAGDIGVGGREIGYLFGQYKKLKNSFE----GVLTGKNIKWGGSNIRAEATGYGV 222 Query: 277 FHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGS 336 + EN + + + +K +V G GNV + + L GA + + +S+G Sbjct: 223 VYFAENVLKD--------LNDNLENKKCLVSGSGNVAQYLVEKLIEKGAIVLTMSDSNGY 274 Query: 337 IWNPDGIDPKEL-------EDFKLQHGSILGFPK-AKPYEGSI-LEADCDILIPAASEKQ 387 I P+G ++L + +L+ L + K AK +E CDI P A++ + Sbjct: 275 ILEPNGFTKEQLNYIMDIKNNQRLRLKEYLKYSKTAKYFENQKPWNIPCDIAFPCATQNE 334 Query: 388 LTKSNAP---RVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLK 444 + +++A + K K+I EGAN PT +A + NI++ P NAGGV VS E + Sbjct: 335 INENDADLFIQNKCKMIVEGANMPTHIKALHKLKQNNIILCPSKAANAGGVAVSGLEMSQ 394 Query: 445 N 445 N Sbjct: 395 N 395 >2YFH-A nrPDB Length = 448 Score = 148 bits (374), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 126/422 (29%), Positives = 195/422 (46%), Gaps = 47/422 (11%) Query: 62 DDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFP 121 D+P F + VE +V+ E EE V + R++ P V+ P Sbjct: 18 DEPEFVQTVEEVLSSLGPVVDAH-------PEYEE-----VALLERMVIP-ERVIEFRVP 64 Query: 122 IRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGG 181 D+G V GYR Q + P KGG+R++ V++ +K L +K ++ +P GG Sbjct: 65 WEDDNGKVHVNTGYRVQFNGAIGPYKGGLRFAPSVNLSIMKFLGFEQAFKDSLTTLPMGG 124 Query: 182 AKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYA 241 AK G +P +D E+ + + F EL + IGP IDVPA D+ G RE+ ++ Y Sbjct: 125 AKGGSDFDPNGKSDREVMRFCQAFMTELYRH--IGPDIDVPAGDLGVGAREIGYMYGQYR 182 Query: 242 STIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGD 301 +G + + +TGK S GG R ATG G+ + E + GM GF Sbjct: 183 KIVGGF---YNGVLTGKARSFGGSLIRPEATGYGLVYFTEAMLKRH------GM--GFEG 231 Query: 302 KTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKEL----EDFKLQHGS 357 V G GNV +++ FGA+ I +S G++ + G ++L E + G Sbjct: 232 MRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKASRDGR 291 Query: 358 ILGFPKAKPYEGSILEAD------CDILIPAASEKQLTKSNAPRVKA---KIIAEGANGP 408 + + AK + LE DI +P A++ +L A ++ A K +AEGAN P Sbjct: 292 VADY--AKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQLIANGVKAVAEGANMP 349 Query: 409 TTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYER-DSNYHLL 467 TT EA ++F + ++ P NAGGV S E +N RL +K E+ D+ H + Sbjct: 350 TTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNA-----ARLGWKAEKVDARLHHI 404 Query: 468 MS 469 M+ Sbjct: 405 MT 406 >5IJZ-A nrPDB Length = 447 Score = 145 bits (365), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 117/377 (31%), Positives = 183/377 (48%), Gaps = 35/377 (9%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 I R+ +P ++ P D G V G+R Q + P KGG+R+ V++ VK L Sbjct: 51 IQRLCEPERQLI-FRVPWVDDQGQVHVNRGFRVQFNSALGPYKGGLRFHPSVNLGIVKFL 109 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 +K ++ +P GG K G +PK +D E+ + + F EL + IG DVPA Sbjct: 110 GFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDLEIMRFCQSFMTELHRH--IGEYRDVPAG 167 Query: 225 DMSTGEREMSWIADTYASTIGHYD--INAH--ACVTGKPISQGGIHGRISATGRGVFHGI 280 D+ G RE+ ++ GHY N H +TGK ++ GG R ATG G + + Sbjct: 168 DIGVGGREIGYL-------FGHYRRMANQHESGVLTGKGLTWGGSLVRTEATGYGCVYFV 220 Query: 281 ENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNP 340 I +A SI G + +V G GNV +++ GA I +S G + P Sbjct: 221 SEMI-KAKGESISG-------QKIIVSGSGNVATYAIEKAQELGATVIGFSDSSGWVHTP 272 Query: 341 DGIDPKELEDFK-LQHGSILGFP---KAKPY--EGSILEADCDILIPAASEKQLTKSNAP 394 +G+D +L + K ++ + + + Y +GSI + CDI +P A++ +L NA Sbjct: 273 NGVDVAKLREIKEVRRARVSVYADEVEGATYHTDGSIWDLKCDIALPCATQNELNGENAK 332 Query: 395 RVK---AKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSY 451 + + +AEGAN P+TPEA ++F ER+I P NAGGV S E +N + S+ Sbjct: 333 TLADNGCRFVAEGANMPSTPEAVEVFRERDIRFGPGKAANAGGVATSALEMQQNASRDSW 392 Query: 452 GRLTFKYERDSNYHLLM 468 +F+Y D ++M Sbjct: 393 ---SFEY-TDERLQVIM 405 >2BMA-A nrPDB Length = 470 Score = 132 bits (332), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 101/348 (29%), Positives = 162/348 (46%), Gaps = 36/348 (10%) Query: 125 DDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKA 184 D+G +R Q++ P KGG+R+ V++ VK L +K ++ + GG K Sbjct: 90 DNGVQRKNRCFRVQYNSALGPYKGGLRFHPSVNLSIVKFLGFEQIFKNSLTGLSMGGGKG 149 Query: 185 GVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTI 244 G +PK +DNE+ K + F EL + IGP DVPA D+ G RE+ ++ Y + Sbjct: 150 GSDFDPKGKSDNEILKFCQAFMNELYRH--IGPCTDVPAGDIGVGGREIGYLYGQYKKIV 207 Query: 245 GHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTF 304 ++ +TGK + GG + R+ ATG G+ + F+ E + + +T Sbjct: 208 NSFN----GTLTGKNVKWGGSNLRVEATGYGLVY----FVLEV----LKSLNIPVEKQTA 255 Query: 305 VVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELE---DFK--------- 352 VV G GNV L+ ++ L K + + +S+G ++ P+G + LE D K Sbjct: 256 VVSGSGNVALYCVQKLLHLNVKVLTLSDSNGYVYEPNGFTHENLEFLIDLKEEKKGRIKE 315 Query: 353 -LQHGSILG-FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAK---IIAEGANG 407 L H S FP KP+ C + P A++ + A ++ ++ EGAN Sbjct: 316 YLNHSSTAKYFPNEKPW-----GVPCTLAFPCATQNDVDLDQAKLLQKNGCILVGEGANM 370 Query: 408 PTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLT 455 P+T +A +F NI+ P NAGGV +S E +N + R T Sbjct: 371 PSTVDAINLFKSNNIIYCPSKAANAGGVAISGLEMSQNFQFSHWTRET 418 >4FHN-X nrPDB Length = 450 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 116/390 (29%), Positives = 180/390 (46%), Gaps = 39/390 (10%) Query: 95 EEQKRNRVRGIL-RIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYS 153 E+ + R +L R+++P V+ D +V +R Q S P KGG+R+ Sbjct: 43 EQNPKYRQMSLLERLVEP-ERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFH 101 Query: 154 TDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKG 213 V++ +K L T+K A+ +P GG K G +PK ++ E+ + + EL + Sbjct: 102 PSVNLSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRH- 160 Query: 214 FIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACV-TGKPISQGGIHGRISAT 272 +G DVPA D+ G RE+ ++A N ACV TGK +S GG R AT Sbjct: 161 -LGADTDVPAGDIGVGGREVGFMAGMMKKL-----SNNTACVFTGKGLSFGGSLIRPEAT 214 Query: 273 GRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGE 332 G G+ + E + GM GF V G GNV +++ FGA+ I + Sbjct: 215 GYGLVYFTEAMLKRH------GM--GFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASD 266 Query: 333 SDGSIWNPDGIDPKEL----EDFKLQHGSILGFPKAKPYEGSILEAD------CDILIPA 382 S G++ + G ++L E + G + + AK + LE DI +P Sbjct: 267 SSGTVVDESGFTKEKLARLIEIKSSRDGRVADY--AKEFGLVYLEGQQPWSVPVDIALPC 324 Query: 383 ASEKQLTKSNAPRVKA---KIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSY 439 A++ +L A ++ A K +AEGAN PTT EA ++F + ++ P NAGGV S Sbjct: 325 ATQNELDVDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSG 384 Query: 440 FEWLKNLNHVSYGRLTFKYER-DSNYHLLM 468 E +N RL +K E+ D+ H +M Sbjct: 385 LEMAQNA-----ARLGWKAEKVDARLHHIM 409 >5XW0-A nrPDB Length = 460 Score = 107 bits (268), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 104/383 (27%), Positives = 163/383 (42%), Gaps = 39/383 (10%) Query: 97 QKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDV 156 QK R L ++ V+ D G+ +V G+R Q + P KGG+R+ V Sbjct: 28 QKNPEYRKALAVVSVPERVIQFRVVWEDDAGNVQVNRGFRVQFNSALGPYKGGLRFHPSV 87 Query: 157 SVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIG 216 ++ +K L +K A+ + GG K G +PK +DNE+ + F EL K IG Sbjct: 88 NLSILKFLGFEQIFKNALTGLNMGGGKGGSDFDPKGKSDNEIRRFCVSFMTELCKH--IG 145 Query: 217 PGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGV 276 DVPA D+ RE+ ++ Y ++ +TGK S GG R ATG GV Sbjct: 146 ADTDVPAGDIGVTGREVGFLFGQYRKIRNQWE----GVLTGKGGSWGGSLIRPEATGYGV 201 Query: 277 FHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGS 336 + +E+ I A+ F K + G GNV ++ + G +++ +S GS Sbjct: 202 VYYVEHMIAHAT-----NGQESFKGKRVAISGSGNVAQYAALKVIELGGSVVSLSDSQGS 256 Query: 337 -IWNPDG-IDPKELE---DFKLQHGSILGFPKAKPYEGS------------ILEADCDIL 379 I N +G P+E+E K++ + A P+ + + D+ Sbjct: 257 LIINGEGSFTPEEIELIAQTKVERKQLASIVGAAPFSDANKFKYIAGARPWVHVGKVDVA 316 Query: 380 IPAASEKQLTKSNAP---RVKAKIIAEGANGPTTPEADKIFLERN--------IMVIPDL 428 +P+A++ +++ A K IAEG+N T EA F I P Sbjct: 317 LPSATQNEISGEEAQVLINAGCKFIAEGSNMGCTQEAIDTFEAHRTANAGAAAIWYAPGK 376 Query: 429 YLNAGGVTVSYFEWLKNLNHVSY 451 NAGGV VS E +N +S+ Sbjct: 377 AANAGGVAVSGLEMAQNSARLSW 399 >5B37-A nrPDB Length = 361 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 86/320 (26%), Positives = 132/320 (41%), Gaps = 56/320 (17%) Query: 132 IEGYRAQHSQHRTPCKGGIRY----STDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVK 187 I+ A H P G R + + ++ + L+ MTYK A ++P GG KA + Sbjct: 25 IKAIIAIHDTTLGPAMGATRILPYINEEAALKDALRLSRGMTYKAACANIPAGGGKAVII 84 Query: 188 INPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHY 247 NP+N TD +L + RF L + G +++ D+ T +E ++ + G Sbjct: 85 ANPENKTD-DLLRAYGRFVDSLNGRFITGQDVNITPDDVRTISQETKYVVGVSEKSGGPA 143 Query: 248 DINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMS--ILGMTPGFGDKTFV 305 I T GVF GI+ + E+ + S + GM Sbjct: 144 PI----------------------TSLGVFLGIKAAV-ESRWQSKRLDGM-------KVA 173 Query: 306 VQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAK 365 VQG GNVG + R+LH E D ++ D +DP + E+ K + G + Sbjct: 174 VQGLGNVGKNLCRHLH----------EHDVQLFVSD-VDPIKAEEVK----RLFGATVVE 218 Query: 366 PYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA--DKIFLERNIM 423 P E I D DI P A L P ++A IIA AN E ++ ++ I+ Sbjct: 219 PTE--IYSLDVDIFAPCALGGILNSHTIPFLQASIIAGAANNQLENEQLHSQMLAKKGIL 276 Query: 424 VIPDLYLNAGGVTVSYFEWL 443 PD +NAGG+ Y E + Sbjct: 277 YSPDYVINAGGLINVYNEMI 296 >6ACF-A nrPDB Length = 367 Score = 72.0 bits (175), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 84/345 (24%), Positives = 130/345 (37%), Gaps = 60/345 (17%) Query: 139 HSQHRTPCKGGIRY----STDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYT 194 H P GG R S + ++++ LA MTYK A + GG K + +P+ Sbjct: 32 HDTTLGPALGGTRMWMYNSEEEALEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDK 91 Query: 195 DNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHAC 254 + + + RF L + + DM +E ++ I+ Sbjct: 92 NEAMFRAFGRFIQGLNGRYITAEDVGTTVADMDIIYQETDYVTG----------ISPEFG 141 Query: 255 VTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGL 314 +G P AT GV+ G++ EA G + K VQG GNV Sbjct: 142 SSGNPSP---------ATAYGVYRGMKAAAKEA-----FG-SDSLEGKVVAVQGVGNVAY 186 Query: 315 HSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEA 374 H R+LH GAK I + ++ + +E+F G P I Sbjct: 187 HLCRHLHEEGAKLIVTDINKEAV-------ARAVEEF--------GAKAVDP--NDIYGV 229 Query: 375 DCDILIPAASEKQLTKSNAPRVKAKIIAEGANGP-TTPEADKIFLERNIMVIPDLYLNAG 433 +CDI P A + P++KAK+IA AN P + E I+ PD +NAG Sbjct: 230 ECDIFAPCALGGIINDQTIPQLKAKVIAGSANNQLKEPRHGDMIHEMGIVYAPDYVINAG 289 Query: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKF 478 GV N+ YG Y R+ + + +++E+ F Sbjct: 290 GVI--------NVADELYG-----YNRERAMKKIEQIYDNIEKVF 321 >3VPX-A nrPDB Length = 364 Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 86/341 (25%), Positives = 127/341 (37%), Gaps = 61/341 (17%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRY----STDVSVDEV 161 + I K H I +D S ++ A H P GG R S + ++++ Sbjct: 1 MEIFKYMEHQDYEQLVICQDKASG--LKAIIAIHDTTLGPALGGTRMWTYASEEEAIEDA 58 Query: 162 KALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDV 221 LA MTYK A + GG K + NPK ++E+ + R+ L + + Sbjct: 59 LRLARGMTYKNAAAGLNLGGGKTVIIGNPKTDKNDEMFRAFGRYIEGLNGRYITAEDVGT 118 Query: 222 PAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIE 281 DM E ++ T +A A +G P T G+++G++ Sbjct: 119 TEADMDLINLETDYVTGT----------SAGAGSSGNP---------SPVTAYGIYYGMK 159 Query: 282 NFINEASYMSILGMTPGFGD-----KTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGS 336 EA FGD KT VQG GNV YLH GAK I Sbjct: 160 AAAKEA-----------FGDDSLAGKTVAVQGVGNVAYALCEYLHEEGAKLIIT------ 202 Query: 337 IWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRV 396 ++ + +Q ++ F I + DI P A + P++ Sbjct: 203 ----------DINEEAVQR-AVDAFGATAVGINEIYSQEADIFAPCALGAIINDETIPQL 251 Query: 397 KAKIIAEGANG--PTTPEADKIFLERNIMVIPDLYLNAGGV 435 KAK+IA AN T D I E I+ PD +N+GGV Sbjct: 252 KAKVIAGSANNQLKETRHGDLIH-EMGIVYAPDYVINSGGV 291 >1BW9-B nrPDB Length = 356 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 78/303 (25%), Positives = 115/303 (37%), Gaps = 50/303 (16%) Query: 140 SQHRTPCKGGIR---YS--TDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKI-NPKNY 193 S P GG R YS D D K LA MT K AV ++P GG K+ + + P++ Sbjct: 32 STQLGPAAGGTRAAQYSQLADALTDAGK-LAGAMTLKMAVSNLPMGGGKSVIALPAPRHS 90 Query: 194 TD-NELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAH 252 D + +I R + K G PD++T +M + DT Sbjct: 91 IDPSTWARILRIHAENIDKL----SGNYWTGPDVNTNSADMDTLNDTT------------ 134 Query: 253 ACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNV 312 V G+ + +GG T GVF ++ + S+ G+ T +VQG G V Sbjct: 135 EFVFGRSLERGGAGSSAFTTAVGVFEAMKATVAHRGLGSLDGL-------TVLVQGLGAV 187 Query: 313 GLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSIL 372 G GA+ + V ++D ++ H LG + +L Sbjct: 188 GGSLASLAAEAGAQLL-VADTDTE---------------RVAHAVALGHTAVALED--VL 229 Query: 373 EADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPE-ADKIFLERNIMVIPDLYLN 431 CD+ P A +T A + ++A AN E A I R I+ PD N Sbjct: 230 STPCDVFAPCAMGGVITTEVARTLDCSVVAGAANNVIADEAASDILHARGILYAPDFVAN 289 Query: 432 AGG 434 AGG Sbjct: 290 AGG 292 >1LEH-A nrPDB Length = 364 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 75/309 (24%), Positives = 109/309 (35%), Gaps = 57/309 (18%) Query: 137 AQHSQHRTPCKGGIRYST----DVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKN 192 A H P GG R T + ++++ LA MTYK A + GG K + +P Sbjct: 30 AIHDTTLGPALGGARMWTYNAEEEAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPFA 89 Query: 193 YTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAH 252 + ++ + RF L + + DM +E + Sbjct: 90 DKNEDMFRALGRFIQGLNGRYITAEDVGTTVDDMDLIHQETDY----------------- 132 Query: 253 ACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTF-----VVQ 307 VTG + G T GV+ G++ EA FG + VQ Sbjct: 133 --VTGISPAFGSSGNPSPVTAYGVYRGMKAAAKEA-----------FGSDSLEGLAVSVQ 179 Query: 308 GFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPY 367 G GNV + L+ GAK + ++ + + G+ P A Sbjct: 180 GLGNVAKALCKKLNTEGAKLVVTD-----------VNKAAVSAAVAEEGADAVAPNA--- 225 Query: 368 EGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGA-NGPTTPEADKIFLERNIMVIP 426 I CDI P A L P++KAK+IA A N P K E I+ P Sbjct: 226 ---IYGVTCDIFAPCALGAVLNDFTIPQLKAKVIAGSADNQLKDPRHGKYLHELGIVYAP 282 Query: 427 DLYLNAGGV 435 D +NAGGV Sbjct: 283 DYVINAGGV 291 >5JY4-B nrPDB Length = 391 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 16/115 (13%) Query: 399 KIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKY 458 +++A A TP+ DK+ L R I + D +++G + E L N VSY F Sbjct: 131 QMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVL----LERLIAQNPVSYN---FHV 183 Query: 459 ERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQ-----DRISG----ASEKD 504 LL + E L RK G+ +IP+ +A Q DR +G ASEKD Sbjct: 184 PLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKD 238 >4W9U-A nrPDB Length = 395 Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust. Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 12/101 (11%) Query: 381 PAASEKQLTKSN-APRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAG-----G 434 P E+QLT+ R AK A P +K +LE P+L+ G G Sbjct: 12 PFLLEEQLTEDERMIRDSAKAFASDV---LLPRVEKAYLEET--TDPELFHLMGQAGLLG 66 Query: 435 VTVSYFEWLKNLNHVSYGRLTFKYER-DSNYHLLMSVQESL 474 VT+ N ++V+YG + + ER DS Y +MSVQ SL Sbjct: 67 VTLPEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSL 107 >5LZ5-A nrPDB Length = 388 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 22/110 (20%) Query: 73 FFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVI 132 F D+ A+ + DK LRT + EE+ R + + K C+ LSL I Sbjct: 145 FKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDI---------- 194 Query: 133 EGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182 H P K + D+ D + S+ K AV+ FGGA Sbjct: 195 --------DHGKPVKNAL----DLKFDMEQLKDSIDREKIAVIGHSFGGA 232 >3GNC-A nrPDB Length = 399 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/30 (53%), Positives = 21/30 (70%), Gaps = 1/30 (3%) Query: 446 LNHVSYGRLTFKYER-DSNYHLLMSVQESL 474 L++VSYG + + ER DS Y +MSVQ SL Sbjct: 81 LDYVSYGLIAREVERVDSGYRSMMSVQSSL 110 >3C98-B nrPDB Length = 279 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 8/63 (12%) Query: 95 EEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYST 154 +E+ NR LRI K + LS F EV+ Y A S +R CKG I+ Sbjct: 114 QEEGLNRSSADLRIRKTQHSTLSRKF--------VEVMSEYNATQSDYRERCKGRIQRQL 165 Query: 155 DVS 157 +++ Sbjct: 166 EIT 168 >2QBO-A nrPDB Length = 421 Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 3/63 (4%) Query: 319 YLHRFGAKCIAVGESDGSIWN--PDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADC 376 Y H F ++C + G ++ P +DP E F+ ++G P E I E C Sbjct: 79 YRH-FSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELAC 137 Query: 377 DIL 379 ++ Sbjct: 138 SLI 140 >1OMO-A nrPDB Length = 322 Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 13/60 (21%) Query: 376 CDILIPAASEKQLTKSNAPRVKAKIIAEG-------ANGPTTPEADKIFLERNIMVIPDL 428 CD+L+ T S P VKA+ + EG A+GP E D L++ +V+ DL Sbjct: 188 CDVLVTT------TPSRKPVVKAEWVEEGTHINAIGADGPGKQELDVEILKKAKIVVDDL 241 >4R3U-C nrPDB Length = 158 Score = 29.3 bits (64), Expect = 5.0, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 7/54 (12%) Query: 504 DIVHSGLAYTMERSARQIMRTAMKYN---LGLDLRTAAYVNAIEKVFKVYNEAG 554 D+++SGL R+ +++ TA++ + LG+ L + + K+FK+ +E G Sbjct: 46 DVIYSGL----HRTPEEVVNTAIQEDVDVLGVSLLSGVQLTVFPKIFKLLDERG 95 >2PAJ-A nrPDB Length = 492 Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 15/63 (23%) Query: 60 REDDPNFFKM---------------VEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRG 104 R DDP +F + V F G +V D L+E + +E + R VR Sbjct: 418 RLDDPRYFGLHDPAIGPVASGGRPSVMALFSAGKRVVVDDLIEGVDIKELGGEARRVVRE 477 Query: 105 ILR 107 +LR Sbjct: 478 LLR 480 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6DHM-A nrPDB 782 0.0 1L1F-A nrPDB 718 0.0 1GTM-A nrPDB 501 e-142 1EUZ-A nrPDB 491 e-139 1B26-A nrPDB 490 e-139 1BVU-A nrPDB 490 e-139 2YFH-A nrPDB 452 e-127 3K92-A nrPDB 446 e-125 3K8Z-A nrPDB 443 e-124 1HRD-A nrPDB 441 e-124 3R3J-A nrPDB 437 e-123 4XGI-A nrPDB 437 e-123 3AOE-A nrPDB 431 e-121 4FHN-X nrPDB 412 e-115 5IJZ-A nrPDB 408 e-114 1V9L-A nrPDB 407 e-114 2YFQ-A nrPDB 399 e-111 2BMA-A nrPDB 391 e-109 5XW0-A nrPDB 376 e-104 3AOE-E nrPDB 349 3e-96 6ACF-A nrPDB 308 3e-84 3VPX-A nrPDB 284 8e-77 1LEH-A nrPDB 279 3e-75 5B37-A nrPDB 260 1e-69 1BW9-B nrPDB 205 6e-53 Sequences not found previously or not previously below threshold: 3G1U-A nrPDB 51 2e-06 3H9U-A nrPDB 42 6e-04 2HAE-A nrPDB 41 0.001 4WEQ-A nrPDB 40 0.003 6GBN-A nrPDB 39 0.005 2A9F-A nrPDB 39 0.007 1CRW-G nrPDB 37 0.023 1XDW-A nrPDB 36 0.049 3ING-A nrPDB 36 0.061 5OFW-B nrPDB 35 0.071 2G76-A nrPDB 35 0.073 2DLD-A nrPDB 35 0.090 2ZJ1-A nrPDB 35 0.091 6JCV-A nrPDB 34 0.13 3NJ4-A nrPDB 34 0.13 4J90-A nrPDB 34 0.14 1DXY-A nrPDB 34 0.15 1J49-A nrPDB 34 0.18 3JSA-A nrPDB 34 0.20 5JXW-A nrPDB 34 0.21 5TX7-A nrPDB 33 0.26 1CDO-A nrPDB 33 0.27 5ZZ6-A nrPDB 33 0.29 2VHY-A nrPDB 33 0.30 3OND-A nrPDB 33 0.31 2D0I-A nrPDB 32 0.46 2VYN-D nrPDB 32 0.51 5M65-A nrPDB 32 0.53 3HG7-A nrPDB 32 0.62 4PRK-A nrPDB 32 0.66 5H82-A nrPDB 32 0.70 4XDY-A nrPDB 32 0.71 2DC1-A nrPDB 32 0.72 5DT9-A nrPDB 32 0.73 2HMT-A nrPDB 32 0.73 5BUT-A nrPDB 32 0.74 3UOG-A nrPDB 32 0.74 5AOV-A nrPDB 32 0.88 6B4O-A nrPDB 32 0.92 3DC2-A nrPDB 32 0.93 4M7W-A nrPDB 31 1.0 1VC2-A nrPDB 31 1.0 6BII-A nrPDB 31 1.0 4CBQ-A nrPDB 31 1.5 3H9E-O nrPDB 31 1.5 1X14-A nrPDB 31 1.6 3EVT-A nrPDB 31 1.6 3DO5-A nrPDB 31 1.7 3D3W-A nrPDB 31 1.8 3N58-A nrPDB 31 1.9 6APH-A nrPDB 31 2.1 3OIG-A nrPDB 31 2.1 3POC-A nrPDB 30 2.2 4RQU-A nrPDB 30 2.3 4DGS-A nrPDB 30 2.6 4S1V-D nrPDB 30 2.7 2EKL-A nrPDB 30 2.9 4YRY-B nrPDB 30 3.0 2CZG-A nrPDB 30 3.2 5C7I-O nrPDB 30 3.3 1V8B-A nrPDB 30 3.3 1URH-A nrPDB 30 3.6 3SLK-A nrPDB 29 3.8 5AVO-A nrPDB 29 3.9 3LK7-A nrPDB 29 4.0 1QP8-A nrPDB 29 4.0 5YCX-A nrPDB 29 4.1 3K5P-A nrPDB 29 4.2 4KUG-A nrPDB 29 4.4 1CYD-A nrPDB 29 4.5 5JFC-L nrPDB 29 4.8 3COS-A nrPDB 29 5.1 3D64-A nrPDB 29 5.4 2LDB-A nrPDB 29 5.4 5E4R-A nrPDB 29 5.8 4XDZ-A nrPDB 29 6.0 3PDI-A nrPDB 29 6.3 3FBG-A nrPDB 29 7.3 4Y4N-A nrPDB 29 7.5 4XRR-A nrPDB 29 7.9 1O89-A nrPDB 29 7.9 5MH6-A nrPDB 29 8.0 5YEQ-A nrPDB 28 8.8 4Y4M-A nrPDB 28 9.0 1VDC-A nrPDB 28 9.3 >6DHM-A nrPDB Length = 582 Score = 782 bits (2020), Expect = 0.0, Method: Composition-based stats. Identities = 535/561 (95%), Positives = 542/561 (96%), Gaps = 3/561 (0%) Query: 1 MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQP---GLALAARRHYSEAV 57 MYR LGEALLLSR GPAALGS +ADSA LLG ARGQ AAA GL ARRHYSEA Sbjct: 22 MYRCLGEALLLSRIGPAALGSVAADSAVLLGRARGQAAAAVAAPQPGLVPPARRHYSEAA 81 Query: 58 ADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLS 117 ADREDDPNFFKMVEGFFDRGASIVEDKLVEDL+TRE+EEQKRNRVRGILRIIKPCNHVLS Sbjct: 82 ADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRGILRIIKPCNHVLS 141 Query: 118 LSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDV 177 LSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDV Sbjct: 142 LSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDV 201 Query: 178 PFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIA 237 PFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPG+DVPAPDMSTGEREMSWIA Sbjct: 202 PFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIA 261 Query: 238 DTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTP 297 DTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTP Sbjct: 262 DTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTP 321 Query: 298 GFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGS 357 GFGDKTF VQGFGNVGLHSMRYLHRFGAKC+AVGESDGSIWNPDGIDPKELEDFKLQHG+ Sbjct: 322 GFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFKLQHGT 381 Query: 358 ILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIF 417 ILGFPKAK YEGSILE DCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIF Sbjct: 382 ILGFPKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIF 441 Query: 418 LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERK 477 LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERK Sbjct: 442 LERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERK 501 Query: 478 FGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA 537 FGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA Sbjct: 502 FGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA 561 Query: 538 AYVNAIEKVFKVYNEAGVTFT 558 AYVNAIEKVF+VYNEAGVTFT Sbjct: 562 AYVNAIEKVFRVYNEAGVTFT 582 >1L1F-A nrPDB Length = 505 Score = 718 bits (1852), Expect = 0.0, Method: Composition-based stats. Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 54 SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCN 113 SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCN Sbjct: 1 SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCN 60 Query: 114 HVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCA 173 HVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCA Sbjct: 61 HVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCA 120 Query: 174 VVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREM 233 VVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREM Sbjct: 121 VVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREM 180 Query: 234 SWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSIL 293 SWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSIL Sbjct: 181 SWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSIL 240 Query: 294 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL 353 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL Sbjct: 241 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL 300 Query: 354 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA 413 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA Sbjct: 301 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA 360 Query: 414 DKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQES 473 DKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQES Sbjct: 361 DKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQES 420 Query: 474 LERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLD 533 LERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLD Sbjct: 421 LERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLD 480 Query: 534 LRTAAYVNAIEKVFKVYNEAGVTFT 558 LRTAAYVNAIEKVFKVYNEAGVTFT Sbjct: 481 LRTAAYVNAIEKVFKVYNEAGVTFT 505 >1GTM-A nrPDB Length = 419 Score = 501 bits (1289), Expect = e-142, Method: Composition-based stats. Identities = 165/452 (36%), Positives = 242/452 (53%), Gaps = 64/452 (14%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 L +K ++ ++ P+ DDGS +V G+R QH+ R P KGGIR+ + ++ VKAL Sbjct: 26 ALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQHNWARGPTKGGIRWHPEETLSTVKAL 85 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 A+ MT+K AV+D+P+GG K G+ ++PK +D E E++ R + + I P D+PAP Sbjct: 86 AAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAIYD--VISPYEDIPAP 143 Query: 225 DMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFI 284 D+ T + M+W+ D Y TI A +TGKP+S GG GRI AT RG + I Sbjct: 144 DVYTNPQIMAWMMDEY-ETISRRKTPAFGIITGKPLSIGGSLGRIEATARGASYTIREAA 202 Query: 285 NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYL-HRFGAKCIAVGESDGSIWNPDGI 343 + ++ G KT +QG+GN G + + + FG K +AV +S G I+NPDG+ Sbjct: 203 KVLGWDTLKG-------KTIAIQGYGNAGYYLAKIMSEDFGMKVVAVSDSKGGIYNPDGL 255 Query: 344 DPKELEDFKLQHGSILGFPKAKPYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIA 402 + E+ +K +HGS+ FP A +LE + D+L PAA E+ +TK NA +KAKI+A Sbjct: 256 NADEVLKWKNEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIKAKIVA 315 Query: 403 EGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDS 462 E ANGP TPEAD+I E+ I+ IPD NAGGVTVSYFEW++N+ Sbjct: 316 EVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNIT--------------G 361 Query: 463 NYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIM 522 Y + V+E L++K T F D + A EK+I Sbjct: 362 YYWTIEEVRERLDKKM-----------TKAFYDVYNIAKEKNIH---------------- 394 Query: 523 RTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAG 554 +R AAYV A+++V++ + G Sbjct: 395 -----------MRDAAYVVAVQRVYQAMLDRG 415 >1EUZ-A nrPDB Length = 419 Score = 491 bits (1264), Expect = e-139, Method: Composition-based stats. Identities = 170/490 (34%), Positives = 243/490 (49%), Gaps = 83/490 (16%) Query: 67 FKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDD 126 F+M +R A ++ SEE L +K ++ +S PI DD Sbjct: 7 FEMAVKQLERAAQYMD----------ISEE--------ALEWLKKPMRIVEVSVPIEMDD 48 Query: 127 GSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGV 186 GS +V G+R QH+ R P KGGIR+ ++ VKALA+ MT+K AVVD+P+GG K G+ Sbjct: 49 GSVKVFTGFRVQHNWARGPTKGGIRWHPAETLSTVKALATWMTWKVAVVDLPYGGGKGGI 108 Query: 187 KINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGH 246 +NPK ++ E E++ R + + IGP D+PAPD+ T + M W+ D Y TI Sbjct: 109 IVNPKELSEREQERLARAYIRAVYD--VIGPWTDIPAPDVYTNPKIMGWMMDEY-ETIMR 165 Query: 247 YDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVV 306 A +TGKP+S GG GR +AT +G I K V Sbjct: 166 RKGPAFGVITGKPLSIGGSLGRGTATAQGAIFTIREAAKALGID--------LKGKKIAV 217 Query: 307 QGFGNVGLHSMRYL-HRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAK 365 QG+GN G ++ + + G +AV +S G I+NPDG+DP E+ +K +HGS+ FP A Sbjct: 218 QGYGNAGYYTAKLAKEQLGMTVVAVSDSRGGIYNPDGLDPDEVLKWKREHGSVKDFPGAT 277 Query: 366 PYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMV 424 +LE + D+L PAA E+ +T+ NA +KAKI+AE ANGP TPEAD I E+ I+ Sbjct: 278 NITNEELLELEVDVLAPAAIEEVITEKNADNIKAKIVAEVANGPVTPEADDILREKGILQ 337 Query: 425 IPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGT 484 IPD NAGGVTVSYFEW++N+N Y V+E L++K Sbjct: 338 IPDFLCNAGGVTVSYFEWVQNIN--------------GYYWTEEEVREKLDKKM------ 377 Query: 485 IPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIE 544 T F + + +K+I +R AAYV A+ Sbjct: 378 -----TKAFWEVYNTHKDKNIH---------------------------MRDAAYVVAVS 405 Query: 545 KVFKVYNEAG 554 +V++ + G Sbjct: 406 RVYQAMKDRG 415 >1B26-A nrPDB Length = 416 Score = 490 bits (1261), Expect = e-139, Method: Composition-based stats. Identities = 189/495 (38%), Positives = 269/495 (54%), Gaps = 85/495 (17%) Query: 63 DPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPI 122 + + ++M F+R AS++ DL + +E +++ VL + FP+ Sbjct: 3 EKSLYEMAVEQFNRAASLM------DLESDLAE------------VLRRPKRVLIVEFPV 44 Query: 123 RRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182 R DDG EV GYR QH+ R P KGGIRY DV++DEVKALA MT+K AV+++PFGG Sbjct: 45 RMDDGHVEVFTGYRVQHNVARGPAKGGIRYHPDVTLDEVKALAFWMTWKTAVMNLPFGGG 104 Query: 183 KAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYAS 242 K GV+++PK + NELE+++RRF E+ + IGP D+PAPD++T ++W DTY+ Sbjct: 105 KGGVRVDPKKLSRNELERLSRRFFSEI--QVIIGPYNDIPAPDVNTNADVIAWYMDTYSM 162 Query: 243 TIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDK 302 +GH VTGKP+ GG GR ATGRGV + M +LG+ P Sbjct: 163 NVGH---TVLGIVTGKPVELGGSKGREEATGRGV------KVCAGLAMDVLGIDP--KKA 211 Query: 303 TFVVQGFGNVGLHSMRYL-HRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGF 361 T VQGFGNVG + + G+K +AV +S G I+NP+G D +EL +K +HG+++ + Sbjct: 212 TVAVQGFGNVGQFAALLISQELGSKVVAVSDSRGGIYNPEGFDVEELIRYKKEHGTVVTY 271 Query: 362 P-KAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420 P + +LE D DIL+PAA E + NA R+KAK + EGANGPTTPEAD+I R Sbjct: 272 PKGERITNEELLELDVDILVPAALEGAIHAGNAERIKAKAVVEGANGPTTPEADEILSRR 331 Query: 421 NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK 480 I+V+PD+ NAGGVTVSYFEW+++L Sbjct: 332 GILVVPDILANAGGVTVSYFEWVQDLQSF------------------------------- 360 Query: 481 HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV 540 F D D V + L M+ + +M+ KYN +D+RTAAY+ Sbjct: 361 ------------FWDL-------DQVRNALEKMMKGAFNDVMKVKEKYN--VDMRTAAYI 399 Query: 541 NAIEKVFKVYNEAGV 555 AI++V + G+ Sbjct: 400 LAIDRVAYATKKRGI 414 >1BVU-A nrPDB Length = 418 Score = 490 bits (1261), Expect = e-139, Method: Composition-based stats. Identities = 166/496 (33%), Positives = 249/496 (50%), Gaps = 85/496 (17%) Query: 61 EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF 120 E DP F++ +R A ++ SEE L +K ++ +S Sbjct: 2 EQDP--FEIAVKQLERAAQYMD----------ISEE--------ALEFLKRPQRIVEVSI 41 Query: 121 PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG 180 P+ DDGS +V G+R Q++ R P KGGIR+ + ++ VKALA+ MT+K AV+D+P+G Sbjct: 42 PVEMDDGSVKVFTGFRVQYNWARGPTKGGIRWHPEETLSTVKALAAWMTWKTAVMDLPYG 101 Query: 181 GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY 240 G K GV NPK +D E E++ R + + I P D+PAPD+ T + M+W+ D Y Sbjct: 102 GGKGGVICNPKEMSDREKERLARGYVRAIYD--VISPYTDIPAPDVYTNPQIMAWMMDEY 159 Query: 241 ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG 300 TI + +TGKP S GGI R+ AT RG + + Sbjct: 160 -ETISRRKDPSFGVITGKPPSVGGIVARMDATARGASYTVREAAKALGMD--------LK 210 Query: 301 DKTFVVQGFGNVGLHSMRYL-HRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSIL 359 KT +QG+GN G + + + +G K +AV ++ G I+NPDG++ E+ +K + GS+ Sbjct: 211 GKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVSDTKGGIYNPDGLNADEVLAWKKKTGSVK 270 Query: 360 GFPKAKPYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFL 418 FP A +LE + D+L P+A E+ +TK NA +KAKI+AE ANGPTTPEAD+I Sbjct: 271 DFPGATNITNEELLELEVDVLAPSAIEEVITKKNADNIKAKIVAELANGPTTPEADEILY 330 Query: 419 ERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKF 478 E+ I++IPD NAGGVTVSYFEW++N+ +Y + + L++K Sbjct: 331 EKGILIIPDFLCNAGGVTVSYFEWVQNIT--------------GDYWTVEETRAKLDKKM 376 Query: 479 GKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAA 538 T F D + EK+I ++R AA Sbjct: 377 -----------TKAFWDVYNTHKEKNI---------------------------NMRDAA 398 Query: 539 YVNAIEKVFKVYNEAG 554 YV A+ +V++ + G Sbjct: 399 YVVAVSRVYQAMKDRG 414 >2YFH-A nrPDB Length = 448 Score = 452 bits (1162), Expect = e-127, Method: Composition-based stats. Identities = 117/430 (27%), Positives = 186/430 (43%), Gaps = 41/430 (9%) Query: 51 RHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIK 110 R +E D+P F + VE +V+ E EE +L + Sbjct: 7 RVIAEVEKKYADEPEFVQTVEEVLSSLGPVVDAH-------PEYEE------VALLERMV 53 Query: 111 PCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTY 170 V+ P D+G V GYR Q + P KGG+R++ V++ +K L + Sbjct: 54 IPERVIEFRVPWEDDNGKVHVNTGYRVQFNGAIGPYKGGLRFAPSVNLSIMKFLGFEQAF 113 Query: 171 KCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGE 230 K ++ +P GGAK G +P +D E+ + + F EL + IGP IDVPA D+ G Sbjct: 114 KDSLTTLPMGGAKGGSDFDPNGKSDREVMRFCQAFMTELYRH--IGPDIDVPAGDLGVGA 171 Query: 231 REMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYM 290 RE+ ++ Y +G + + +TGK S GG R ATG G+ + E + Sbjct: 172 REIGYMYGQYRKIVGGF---YNGVLTGKARSFGGSLIRPEATGYGLVYFTEAMLKRHGM- 227 Query: 291 SILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKEL-- 348 GF V G GNV +++ FGA+ I +S G++ + G ++L Sbjct: 228 -------GFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLAR 280 Query: 349 --EDFKLQHGSILGFPK----AKPYEGSILEADCDILIPAASEKQLTKSNAPRVKA---K 399 E + G + + K DI +P A++ +L A ++ A K Sbjct: 281 LIEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQLIANGVK 340 Query: 400 IIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYE 459 +AEGAN PTT EA ++F + ++ P NAGGV S E +N + + + Sbjct: 341 AVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLGWK----AEK 396 Query: 460 RDSNYHLLMS 469 D+ H +M+ Sbjct: 397 VDARLHHIMT 406 >3K92-A nrPDB Length = 424 Score = 446 bits (1147), Expect = e-125, Method: Composition-based stats. Identities = 132/409 (32%), Positives = 216/409 (52%), Gaps = 38/409 (9%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 + ++K +L++ P++ D+GS +V GYR+QH+ P KGG+R+ +V+ ++VKAL Sbjct: 38 MYELMKEPQRMLTVRIPVKMDNGSVKVFTGYRSQHNDAVGPTKGGVRFHPEVNEEKVKAL 97 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 + MT KC + ++P+GG K G+ +P+ + ELE+++R + +++ +GP D+PAP Sbjct: 98 SIWMTLKCGIANLPYGGGKGGIICDPRTMSFGELERLSRGYVRAISQ--IVGPTKDIPAP 155 Query: 225 DMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFI 284 D+ T + M+W+ D Y+ + ++ +TGKP+ GG GR +AT +GV IE + Sbjct: 156 DVYTNSQIMAWMMDEYSRL---REFDSPGFITGKPLVLGGSQGRETATAQGVTICIEEAV 212 Query: 285 NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGID 344 + + ++QGFGN G +++H GAK I + +++G ++NPDG+D Sbjct: 213 KKKGIK--------LQNARIIIQGFGNAGSFLAKFMHDAGAKVIGISDANGGLYNPDGLD 264 Query: 345 PKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEG 404 L D + G + +LE DCDIL+PAA Q+T NA ++A I+ E Sbjct: 265 IPYLLDKRDSFGMVTNLFTDVITNEELLEKDCDILVPAAISNQITAKNAHNIQASIVVER 324 Query: 405 ANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNY 464 ANGPTT +A KI ER ++++PD+ +AGGVTVSYFEW++N Y Sbjct: 325 ANGPTTIDATKILNERGVLLVPDILASAGGVTVSYFEWVQN--------------NQGYY 370 Query: 465 HLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYT 513 V E L + F+ A+ + AY Sbjct: 371 WSEEEVAEKLRSVM-----------VSSFETIYQTAATHKVDMRLAAYM 408 >3K8Z-A nrPDB Length = 423 Score = 443 bits (1138), Expect = e-124, Method: Composition-based stats. Identities = 145/450 (32%), Positives = 229/450 (50%), Gaps = 66/450 (14%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 + ++K +L++ P+R DDGS ++ GYRA H+ P KGGIR+ +V+ EVKAL Sbjct: 38 VYELLKEPMRLLTVKIPVRMDDGSVKIFTGYRA-HNDSVGPTKGGIRFHPNVTEKEVKAL 96 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 + M+ KC ++D+P+GG K G+ +P++ + ELE+++R + +++ +GP DVPAP Sbjct: 97 SIWMSLKCGIIDLPYGGGKGGIVCDPRDMSFRELERLSRGYVRAISQ--IVGPTKDVPAP 154 Query: 225 DMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFI 284 D+ T + M+W+ D Y+ + N+ +TGKP+ GG HGR SAT +GV I+ Sbjct: 155 DVFTNSQIMAWMMDEYSRI---DEFNSPGFITGKPLVLGGSHGRESATAKGVTICIKEAA 211 Query: 285 NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGID 344 + VVQGFGN G + +++H GAK + + ++ G +++P+G+D Sbjct: 212 KKRGID--------IKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLD 263 Query: 345 PKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEG 404 L D + G++ +LE DCDIL+PAA E Q+T+ NA ++AKI+ E Sbjct: 264 IDYLLDRRDSFGTVTKLFNDTITNQELLELDCDILVPAAIENQITEENAHNIRAKIVVEA 323 Query: 405 ANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNY 464 ANGPTT E KI +R+I+++PD+ +AGGVTVSYFEW++N + Sbjct: 324 ANGPTTLEGTKILSDRDILLVPDVLASAGGVTVSYFEWVQNNQGFYWSEEE--------- 374 Query: 465 HLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRT 524 V L M +S I Sbjct: 375 -----------------------------------------VEEKLEKMMVKSFNNIYE- 392 Query: 525 AMKYNLGLDLRTAAYVNAIEKVFKVYNEAG 554 M N +D+R AAY+ + K+ + G Sbjct: 393 -MANNRRIDMRLAAYMVGVRKMAEASRFRG 421 >1HRD-A nrPDB Length = 449 Score = 441 bits (1133), Expect = e-124, Method: Composition-based stats. Identities = 126/438 (28%), Positives = 196/438 (44%), Gaps = 55/438 (12%) Query: 51 RHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIK 110 R +E D+P F + VE +V+ E EE +L + Sbjct: 6 RVIAEVEKKYADEPEFVQTVEEVLSSLGPVVDAH-------PEYEE------VALLERMV 52 Query: 111 PCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTY 170 V+ P D+G V GYR Q + P KGG+R++ V++ +K L + Sbjct: 53 IPERVIEFRVPWEDDNGKVHVNTGYRVQFNGAIGPYKGGLRFAPSVNLSIMKFLGFEQAF 112 Query: 171 KCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGE 230 K ++ +P GGAK G +P +D E+ + + F EL + IGP IDVPA D+ G Sbjct: 113 KDSLTTLPMGGAKGGSDFDPNGKSDREVMRFCQAFMTELYRH--IGPDIDVPAGDLGVGA 170 Query: 231 REMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYM 290 RE+ ++ Y +G + + +TGK S GG R ATG G + +E + Sbjct: 171 REIGYMYGQYRKIVGGF---YNGVLTGKARSFGGSLVRPEATGYGSVYYVEAVMKHE--- 224 Query: 291 SILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKE--- 347 KT + GFGNV + + L GAK + + DG I++P+GI +E Sbjct: 225 -----NDTLVGKTVALAGFGNVAWGAAKKLAELGAKAVTLSGPDGYIYDPEGITTEEKIN 279 Query: 348 ------------LEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPR 395 ++D+ + G + FP KP DI++P A++ + A + Sbjct: 280 YMLEMRASGRNKVQDYADKFG-VQFFPGEKP-----WGQKVDIIMPCATQNDVDLEQAKK 333 Query: 396 VKA---KIIAEGANGPTTPEADKIFLER-NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSY 451 + A K E AN PTT EA + +++ N++V P +NAGGV VS FE +N +S+ Sbjct: 334 IVANNVKYYIEVANMPTTNEALRFLMQQPNMVVAPSKAVNAGGVLVSGFEMSQNSERLSW 393 Query: 452 GRLTFKYERDSNYHLLMS 469 E DS H +M+ Sbjct: 394 T----AEEVDSKLHQVMT 407 >3R3J-A nrPDB Length = 456 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 113/461 (24%), Positives = 195/461 (42%), Gaps = 41/461 (8%) Query: 55 EAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNH 114 + V+ +++P F + E + +K N G+L I Sbjct: 22 KVVSKNKNEPEFLQAFEEVLSCLKPVF---------------KKDNVYIGVLENIAEPER 66 Query: 115 VLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAV 174 V+ P D G ++ G+R Q++ P KGG+R+ V++ +K L +K ++ Sbjct: 67 VIQFRVPWINDKGEHKMNRGFRVQYNSVLGPYKGGLRFHPAVNLSVIKFLGFEQIFKNSL 126 Query: 175 VDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMS 234 +P GG K G +PK ++NE+ K + F L + +IGP DVPA D+ G RE+ Sbjct: 127 TTLPMGGGKGGSDFDPKGKSENEILKFCQSFMTNLFR--YIGPNTDVPAGDIGVGGREIG 184 Query: 235 WIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILG 294 ++ Y ++ +TGK I GG + R ATG GV + EN + + Sbjct: 185 YLFGQYKKLKNSFE----GVLTGKNIKWGGSNIRAEATGYGVVYFAENVLKD-------- 232 Query: 295 MTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKEL------ 348 + +K +V G GNV + + L GA + + +S+G I P+G ++L Sbjct: 233 LNDNLENKKCLVSGSGNVAQYLVEKLIEKGAIVLTMSDSNGYILEPNGFTKEQLNYIMDI 292 Query: 349 -EDFKLQHGSILGFPKAKPY--EGSILEADCDILIPAASEKQLTKSNAP---RVKAKIIA 402 + +L+ L + K Y CDI P A++ ++ +++A + K K+I Sbjct: 293 KNNQRLRLKEYLKYSKTAKYFENQKPWNIPCDIAFPCATQNEINENDADLFIQNKCKMIV 352 Query: 403 EGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDS 462 EGAN PT +A + NI++ P NAGGV VS E +N + + + + Sbjct: 353 EGANMPTHIKALHKLKQNNIILCPSKAANAGGVAVSGLEMSQNSMRLQWTHQETDMKLQN 412 Query: 463 NYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEK 503 + + + + + A F E+ Sbjct: 413 IMKSIYEQCHNTSKIYLNESDLVAGANIAGFLKVADSFLEQ 453 >4XGI-A nrPDB Length = 436 Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats. Identities = 156/389 (40%), Positives = 218/389 (56%), Gaps = 20/389 (5%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 + +K +L + PI D+G+ EGYR QH+ R P KGG+RY DV++ EV AL+ Sbjct: 49 IETLKRPKRILIVDVPIELDNGTVAHFEGYRVQHNVSRGPGKGGVRYHQDVTLSEVMALS 108 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 + M+ K A V+VP+GGAK G++++P+ + ELE++TRR+T E+ IGP D+PAPD Sbjct: 109 AWMSVKNAAVNVPYGGAKGGIRVDPRKLSRGELERVTRRYTSEIG--IIIGPNTDIPAPD 166 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIN 285 ++T E+ M+W+ DTY+ G A VTGKPIS GG GR ATGRGVF Sbjct: 167 VNTNEQIMAWMMDTYSMNQGQ---TATGVVTGKPISLGGSLGRKEATGRGVFVVGCEAAK 223 Query: 286 EASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDP 345 + VQGFGNVG + + GAK IAV + G+I P G+D Sbjct: 224 KKGVE--------IEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQDHTGTIHQPAGVDT 275 Query: 346 KELEDFKLQHGSILGFPKAKPYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEG 404 +L D + G + GF A+P + +ILIPAA E Q+T+ NA +++ KII EG Sbjct: 276 AKLLDHVGRTGGVAGFEGAEPMPNDEFWTVETEILIPAALENQITEKNASKIRTKIIVEG 335 Query: 405 ANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNY 464 ANGPTT AD I ++VIPD+ NAGGVTVSYFEW+++ + F E + N+ Sbjct: 336 ANGPTTTAADDILSANGVLVIPDVIANAGGVTVSYFEWVQDFSSF------FWTEDEINH 389 Query: 465 HLLMSVQESLERKFGKHGGTIPIVPTAEF 493 L ++E+ + V TA F Sbjct: 390 RLERVMREAFAGVWAVAEEHKVSVRTAAF 418 >3AOE-A nrPDB Length = 424 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 159/394 (40%), Positives = 227/394 (57%), Gaps = 20/394 (5%) Query: 101 RVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDE 160 R+ + +K VL + P+R DDGS EGYR H+ R P KGG+RY +V++ E Sbjct: 32 RLAPLAESLKRPKRVLIVDVPVRLDDGSVAYFEGYRVHHNTARGPAKGGVRYHPEVTLSE 91 Query: 161 VKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGID 220 V ALA MT K A V +P+GG K G++++P+ + ELE++TRR+T E+ +GP D Sbjct: 92 VMALAGWMTIKNAAVGLPYGGGKGGIRVDPRKLSPGELERLTRRYTSEIG--ILLGPDRD 149 Query: 221 VPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGI 280 +PAPD++TGEREM+W+ DTY+ +G VTGKPI+ GG GR ATGRGVF Sbjct: 150 IPAPDVNTGEREMAWMMDTYSMNVGR---TVPGVVTGKPIALGGSLGRRDATGRGVFITA 206 Query: 281 ENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNP 340 + +QGFGNVG + R H GA+ +AV + G+++N Sbjct: 207 AAAAEKIGLQ--------VEGARVAIQGFGNVGNAAARAFHDHGARVVAVQDHTGTVYNE 258 Query: 341 DGIDPKELEDFKLQHGSILGFPKAKPYE-GSILEADCDILIPAASEKQLTKSNAPRVKAK 399 GIDP +L + G + G+PKA+P + L+PAA EKQ+T+ NA R++A+ Sbjct: 259 AGIDPYDLLRHVQEFGGVRGYPKAEPLPAADFWGLPVEFLVPAALEKQITEQNAWRIRAR 318 Query: 400 IIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYE 459 I+AEGANGPTTP AD I LE+ ++V+PD+ NAGGVTVSYFEW+++ N F E Sbjct: 319 IVAEGANGPTTPAADDILLEKGVLVVPDVIANAGGVTVSYFEWVQDFNSY------FWTE 372 Query: 460 RDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEF 493 + N L ++ + E + + TA + Sbjct: 373 EEINARLERVLRNAFEAVWQVAQEKKIPLRTAAY 406 >4FHN-X nrPDB Length = 450 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 104/427 (24%), Positives = 170/427 (39%), Gaps = 42/427 (9%) Query: 53 YSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPC 112 + + F + V + E+ + R +L + Sbjct: 14 LNHVQKRDPNQTEFAQAVREVMTTLWPFL-------------EQNPKYRQMSLLERLVEP 60 Query: 113 NHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKC 172 V+ D +V +R Q S P KGG+R+ V++ +K L T+K Sbjct: 61 ERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKN 120 Query: 173 AVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGERE 232 A+ +P GG K G +PK ++ E+ + + EL + +G DVPA D+ G RE Sbjct: 121 ALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRH--LGADTDVPAGDIGVGGRE 178 Query: 233 MSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSI 292 + ++A N TGK +S GG R ATG G+ + E + Sbjct: 179 VGFMAGMMKKLSN----NTACVFTGKGLSFGGSLIRPEATGYGLVYFTEAMLKRHGM--- 231 Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKEL---- 348 GF V G GNV +++ FGA+ I +S G++ + G ++L Sbjct: 232 -----GFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLI 286 Query: 349 EDFKLQHGSILGFPK----AKPYEGSILEADCDILIPAASEKQLTKSNAPRVKA---KII 401 E + G + + K DI +P A++ +L A ++ A K + Sbjct: 287 EIKSSRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQLIANGVKAV 346 Query: 402 AEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERD 461 AEGAN PTT EA ++F + ++ P NAGGV S E +N + + + D Sbjct: 347 AEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLGWK----AEKVD 402 Query: 462 SNYHLLM 468 + H +M Sbjct: 403 ARLHHIM 409 >5IJZ-A nrPDB Length = 447 Score = 408 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 112/426 (26%), Positives = 186/426 (43%), Gaps = 39/426 (9%) Query: 52 HYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKP 111 +Y + +P F + V + ++ E+ G+++ + Sbjct: 10 YYDMLLKRNAGEPEFHQAVAEVLESLKIVL-------------EKDPHYADYGLIQRLCE 56 Query: 112 CNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYK 171 L P D G V G+R Q + P KGG+R+ V++ VK L +K Sbjct: 57 PERQLIFRVPWVDDQGQVHVNRGFRVQFNSALGPYKGGLRFHPSVNLGIVKFLGFEQIFK 116 Query: 172 CAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGER 231 ++ +P GG K G +PK +D E+ + + F EL + IG DVPA D+ G R Sbjct: 117 NSLTGLPIGGGKGGSDFDPKGKSDLEIMRFCQSFMTELHRH--IGEYRDVPAGDIGVGGR 174 Query: 232 EMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMS 291 E+ ++ Y ++ +TGK ++ GG R ATG G + + I Sbjct: 175 EIGYLFGHYRRMANQHES---GVLTGKGLTWGGSLVRTEATGYGCVYFVSEMIKAKG--- 228 Query: 292 ILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDF 351 + +V G GNV +++ GA I +S G + P+G+D +L + Sbjct: 229 -----ESISGQKIIVSGSGNVATYAIEKAQELGATVIGFSDSSGWVHTPNGVDVAKLREI 283 Query: 352 K-LQHGSILGFPKAKP-----YEGSILEADCDILIPAASEKQLTKSNAPRV---KAKIIA 402 K ++ + + +GSI + CDI +P A++ +L NA + + +A Sbjct: 284 KEVRRARVSVYADEVEGATYHTDGSIWDLKCDIALPCATQNELNGENAKTLADNGCRFVA 343 Query: 403 EGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDS 462 EGAN P+TPEA ++F ER+I P NAGGV S E +N + S+ +F+Y D Sbjct: 344 EGANMPSTPEAVEVFRERDIRFGPGKAANAGGVATSALEMQQNASRDSW---SFEY-TDE 399 Query: 463 NYHLLM 468 ++M Sbjct: 400 RLQVIM 405 >1V9L-A nrPDB Length = 421 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 142/456 (31%), Positives = 220/456 (48%), Gaps = 71/456 (15%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 +I+ VL ++ P+R D G +EV EGYR QH P KGG+R+ +V++ + ALA Sbjct: 28 YKILSRPRRVLIVNIPVRLDGGGFEVFEGYRVQHCDVLGPYKGGVRFHPEVTLADDVALA 87 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 LMT K ++ +P+GGAK V+++PK + ELE+++R + +A IG +D+PAPD Sbjct: 88 ILMTLKNSLAGLPYGGAKGAVRVDPKKLSQRELEELSRGYARAIAP--LIGDVVDIPAPD 145 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIN 285 + T + M+W+ D Y+ G+ N T KP G R ATG GV Sbjct: 146 VGTNAQIMAWMVDEYSKIKGY---NVPGVFTSKPPELWGNPVREYATGFGVAVATREMAK 202 Query: 286 EASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDP 345 + + G KT +QG GNVG + +L + GAK IAV + +G + +G++ Sbjct: 203 K--------LWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVAYRKEGLNV 254 Query: 346 KELEDFKLQHGSILG--FPKAKPYE-----GSILEADCDILIPAASEKQLTKSNAPRVKA 398 + ++ K G L F E +I + D DI +PAA E + NA VKA Sbjct: 255 ELIQKNKGLTGPALVELFTTKDNAEFVKNPDAIFKLDVDIFVPAAIENVIRGDNAGLVKA 314 Query: 399 KIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKY 458 +++ EGANGPTTPEA++I ER ++V+PD+ NAGGV +SY EW++NL + Sbjct: 315 RLVVEGANGPTTPEAERILYERGVVVVPDILANAGGVIMSYLEWVENLQWYIWD------ 368 Query: 459 ERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSA 518 ++ LE +I+ + + +R Sbjct: 369 --------EEETRKRLE----------------------------NIMVNNVERVYKRWQ 392 Query: 519 RQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAG 554 R+ G +R AA V A+E+++ G Sbjct: 393 RE---------KGWTMRDAAIVTALERIYNAMKIRG 419 >2YFQ-A nrPDB Length = 421 Score = 399 bits (1025), Expect = e-111, Method: Composition-based stats. Identities = 129/366 (35%), Positives = 206/366 (56%), Gaps = 18/366 (4%) Query: 105 ILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKAL 164 + ++K V+ +S P++ DDG+ +V +G+R+ HS P KGG+R+ +V++DEVKAL Sbjct: 28 VYELLKEPQRVIEISIPVKMDDGTVKVFKGWRSAHSSAVGPSKGGVRFHPNVNMDEVKAL 87 Query: 165 ASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAP 224 + MT+K + +P+GG K G+ ++P ++ ELE+++R + L K ++G ID+PAP Sbjct: 88 SLWMTFKGGALGLPYGGGKGGICVDPAELSERELEQLSRGWVRGLYK--YLGDRIDIPAP 145 Query: 225 DMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFI 284 D++T + MSW D Y G TGKP++ GG GR ATG GV + Sbjct: 146 DVNTNGQIMSWFVDEYVKLNGERMD--IGTFTGKPVAFGGSEGRNEATGFGVAVVVRESA 203 Query: 285 NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDG-----SIWN 339 D VQGFGNVG +++ + R G K A+ E D +++N Sbjct: 204 KRFGIK--------MEDAKIAVQGFGNVGTFTVKNIERQGGKVCAIAEWDRNEGNYALYN 255 Query: 340 PDGIDPKELEDFKLQHGSILGFPKAK-PYEGSILEADCDILIPAASEKQLTKSNAPRVKA 398 +GID KEL +K + +++GFP A+ + + DI++PAA E +T A + A Sbjct: 256 ENGIDFKELLAYKEANKTLIGFPGAERITDEEFWTKEYDIIVPAALENVITGERAKTINA 315 Query: 399 KIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKY 458 K++ E ANGPTTPE DK+ ER I + PD+ N+GGV VSY+EW++N + + Sbjct: 316 KLVCEAANGPTTPEGDKVLTERGINLTPDILTNSGGVLVSYYEWVQNQYGYYWTEAEVEE 375 Query: 459 ERDSNY 464 +++++ Sbjct: 376 KQEADM 381 >2BMA-A nrPDB Length = 470 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 105/479 (21%), Positives = 184/479 (38%), Gaps = 52/479 (10%) Query: 52 HYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKP 111 Y + + F + + + + I+ + Sbjct: 32 VYERVMKLDPNQVEFLQAFHEILYSLKPLF---------------MEEPKYLPIIETLSE 76 Query: 112 CNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYK 171 + D+G +R Q++ P KGG+R+ V++ VK L +K Sbjct: 77 PERAIQFRVCWLDDNGVQRKNRCFRVQYNSALGPYKGGLRFHPSVNLSIVKFLGFEQIFK 136 Query: 172 CAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGER 231 ++ + GG K G +PK +DNE+ K + F EL + IGP DVPA D+ G R Sbjct: 137 NSLTGLSMGGGKGGSDFDPKGKSDNEILKFCQAFMNELYRH--IGPCTDVPAGDIGVGGR 194 Query: 232 EMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMS 291 E+ ++ Y + ++ +TGK + GG + R+ ATG G+ + + + Sbjct: 195 EIGYLYGQYKKIVNSFN----GTLTGKNVKWGGSNLRVEATGYGLVYFVLEVLK------ 244 Query: 292 ILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKEL--- 348 + +T VV G GNV L+ ++ L K + + +S+G ++ P+G + L Sbjct: 245 --SLNIPVEKQTAVVSGSGNVALYCVQKLLHLNVKVLTLSDSNGYVYEPNGFTHENLEFL 302 Query: 349 ----EDFKLQHGSILGF-PKAKPYEGSI-LEADCDILIPAASEKQLTKSNAPRVK---AK 399 E+ K + L AK + C + P A++ + A ++ Sbjct: 303 IDLKEEKKGRIKEYLNHSSTAKYFPNEKPWGVPCTLAFPCATQNDVDLDQAKLLQKNGCI 362 Query: 400 IIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYE 459 ++ EGAN P+T +A +F NI+ P NAGGV +S E +N + R T Sbjct: 363 LVGEGANMPSTVDAINLFKSNNIIYCPSKAANAGGVAISGLEMSQNFQFSHWTRET---- 418 Query: 460 RDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSA 518 D +M R + T D +GA+ + +Y + Sbjct: 419 VDEKLKEIM-------RNIFIACSENALKYTKNKYDLQAGANIAGFLKVAESYIEQGCF 470 >5XW0-A nrPDB Length = 460 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 113/434 (26%), Positives = 179/434 (41%), Gaps = 56/434 (12%) Query: 63 DPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPI 122 +P F E + AS +E+ + QK R L ++ V+ Sbjct: 7 EPEF----EQAYKELASTLENSTLF---------QKNPEYRKALAVVSVPERVIQFRVVW 53 Query: 123 RRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182 D G+ +V G+R Q + P KGG+R+ V++ +K L +K A+ + GG Sbjct: 54 EDDAGNVQVNRGFRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLNMGGG 113 Query: 183 KAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYAS 242 K G +PK +DNE+ + F EL K IG DVPA D+ RE+ ++ Y Sbjct: 114 KGGSDFDPKGKSDNEIRRFCVSFMTELCKH--IGADTDVPAGDIGVTGREVGFLFGQYRK 171 Query: 243 TIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDK 302 ++ +TGK S GG R ATG GV + +E+ I A+ F K Sbjct: 172 IRNQWE----GVLTGKGGSWGGSLIRPEATGYGVVYYVEHMIAHAT-----NGQESFKGK 222 Query: 303 TFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGS-IWNPDG-IDPKELE---DFKLQHGS 357 + G GNV ++ + G +++ +S GS I N +G P+E+E K++ Sbjct: 223 RVAISGSGNVAQYAALKVIELGGSVVSLSDSQGSLIINGEGSFTPEEIELIAQTKVERKQ 282 Query: 358 ILGFPKAKPYEGS------------ILEADCDILIPAASEKQLTKSNAP---RVKAKIIA 402 + A P+ + + D+ +P+A++ +++ A K IA Sbjct: 283 LASIVGAAPFSDANKFKYIAGARPWVHVGKVDVALPSATQNEISGEEAQVLINAGCKFIA 342 Query: 403 EGANGPTTPEADKIFLERN--------IMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRL 454 EG+N T EA F I P NAGGV VS E +N +S+ Sbjct: 343 EGSNMGCTQEAIDTFEAHRTANAGAAAIWYAPGKAANAGGVAVSGLEMAQNSARLSWTSE 402 Query: 455 TFKYERDSNYHLLM 468 E D+ +M Sbjct: 403 ----EVDARLKDIM 412 >3AOE-E nrPDB Length = 419 Score = 349 bits (894), Expect = 3e-96, Method: Composition-based stats. Identities = 116/362 (32%), Positives = 177/362 (48%), Gaps = 16/362 (4%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALA 165 L + +++LS P+ DDG + +GYR H R P KGG+R V++ + LA Sbjct: 36 LEYLAHPKRLVTLSLPVVMDDGKVRIFQGYRVVHDIARGPAKGGVRLDPGVTLGQTAGLA 95 Query: 166 SLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPD 225 + MT K AV D+PFGGA G+ ++PK + ELE++ RR+T EL IGP D+ PD Sbjct: 96 AWMTLKAAVYDLPFGGAAGGIAVDPKGLSPQELERLVRRYTAELVG--LIGPDSDILGPD 153 Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIN 285 + ++ M+WI DTY+ T+G VTGKP + GG GR A G G +E Sbjct: 154 LGADQQVMAWIMDTYSMTVGS---TVPGVVTGKPHALGGSEGRDDAAGLGALLVLEALAK 210 Query: 286 EASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDP 345 VVQG G VG + R G + +AV S G ++ P+G+D Sbjct: 211 RRGLD--------LRGARVVVQGLGQVGAAVALHAERLGMRVVAVATSMGGMYAPEGLDV 262 Query: 346 KELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGA 405 E+ GS+ P+ + + ++L+ AA E L A +V+A+ + E A Sbjct: 263 AEVLSAYEATGSL---PRLDLAPEEVFGLEAEVLVLAAREGALDGDRARQVQAQAVVEVA 319 Query: 406 NGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYH 465 N PEA+ L + +V+PDL GG+ SY EW+++LN + + ++ Sbjct: 320 NFGLNPEAEAYLLGKGALVVPDLLSGGGGLLASYLEWVQDLNMFFWSPEEVRERFETRVA 379 Query: 466 LL 467 + Sbjct: 380 RV 381 >6ACF-A nrPDB Length = 367 Score = 308 bits (789), Expect = 3e-84, Method: Composition-based stats. Identities = 84/379 (22%), Positives = 132/379 (34%), Gaps = 62/379 (16%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYS----TDVSVDEV 161 + + + +D S ++ H P GG R + ++++ Sbjct: 1 MELFQYMEKYDYEQVLFCQDKESG--LKAIIVIHDTTLGPALGGTRMWMYNSEEEALEDA 58 Query: 162 KALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDV 221 LA MTYK A + GG K + +P+ + + + RF L + + Sbjct: 59 LRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGT 118 Query: 222 PAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIE 281 DM +E + VTG G AT GV+ G++ Sbjct: 119 TVADMDIIYQETDY-------------------VTGISPEFGSSGNPSPATAYGVYRGMK 159 Query: 282 NFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD 341 EA + K VQG GNV H R+LH GAK I Sbjct: 160 AAAKEAFG------SDSLEGKVVAVQGVGNVAYHLCRHLHEEGAKLIVTD---------- 203 Query: 342 GIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKII 401 I+ + + + G+ P I +CDI P A + P++KAK+I Sbjct: 204 -INKEAVARAVEEFGAKAVDP------NDIYGVECDIFAPCALGGIINDQTIPQLKAKVI 256 Query: 402 AEGANGP-TTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYER 460 A AN P + E I+ PD +NAGGV N+ YG Y R Sbjct: 257 AGSANNQLKEPRHGDMIHEMGIVYAPDYVINAGGVI--------NVADELYG-----YNR 303 Query: 461 DSNYHLLMSVQESLERKFG 479 + + + +++E+ F Sbjct: 304 ERAMKKIEQIYDNIEKVFA 322 >3VPX-A nrPDB Length = 364 Score = 284 bits (726), Expect = 8e-77, Method: Composition-based stats. Identities = 83/379 (21%), Positives = 127/379 (33%), Gaps = 62/379 (16%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYS----TDVSVDEV 161 + I K H I +D S ++ A H P GG R + ++++ Sbjct: 1 MEIFKYMEHQDYEQLVICQDKASG--LKAIIAIHDTTLGPALGGTRMWTYASEEEAIEDA 58 Query: 162 KALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDV 221 LA MTYK A + GG K + NPK ++E+ + R+ L + + Sbjct: 59 LRLARGMTYKNAAAGLNLGGGKTVIIGNPKTDKNDEMFRAFGRYIEGLNGRYITAEDVGT 118 Query: 222 PAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIE 281 DM E + VTG G T G+++G++ Sbjct: 119 TEADMDLINLETDY-------------------VTGTSAGAGSSGNPSPVTAYGIYYGMK 159 Query: 282 NFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD 341 EA KT VQG GNV YLH GAK I Sbjct: 160 AAAKEAFG------DDSLAGKTVAVQGVGNVAYALCEYLHEEGAKLIITD---------- 203 Query: 342 GIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKII 401 I+ + ++ G I + DI P A + P++KAK+I Sbjct: 204 -INEEAVQRAVDAFG------ATAVGINEIYSQEADIFAPCALGAIINDETIPQLKAKVI 256 Query: 402 AEGANGP-TTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYER 460 A AN + E I+ PD +N+GGV N+ G Y R Sbjct: 257 AGSANNQLKETRHGDLIHEMGIVYAPDYVINSGGVI--------NVADELDG-----YNR 303 Query: 461 DSNYHLLMSVQESLERKFG 479 + + + + + + F Sbjct: 304 ERALKRVEGIYDVIGKIFA 322 >1LEH-A nrPDB Length = 364 Score = 279 bits (712), Expect = 3e-75, Method: Composition-based stats. Identities = 84/379 (22%), Positives = 129/379 (34%), Gaps = 62/379 (16%) Query: 106 LRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYS----TDVSVDEV 161 + I K +D+ S ++ A H P GG R + ++++ Sbjct: 1 MEIFKYMEKYDYEQLVFCQDEASG--LKAVIAIHDTTLGPALGGARMWTYNAEEEAIEDA 58 Query: 162 KALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDV 221 LA MTYK A + GG K + +P + ++ + RF L + + Sbjct: 59 LRLARGMTYKNAAAGLNLGGGKTVIIGDPFADKNEDMFRALGRFIQGLNGRYITAEDVGT 118 Query: 222 PAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIE 281 DM +E + VTG + G T GV+ G++ Sbjct: 119 TVDDMDLIHQETDY-------------------VTGISPAFGSSGNPSPVTAYGVYRGMK 159 Query: 282 NFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD 341 EA + VQG GNV + L+ GAK + Sbjct: 160 AAAKEAFG------SDSLEGLAVSVQGLGNVAKALCKKLNTEGAKLVVTD---------- 203 Query: 342 GIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKII 401 ++ + + G+ P A I CDI P A L P++KAK+I Sbjct: 204 -VNKAAVSAAVAEEGADAVAPNA------IYGVTCDIFAPCALGAVLNDFTIPQLKAKVI 256 Query: 402 AEGA-NGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYER 460 A A N P K E I+ PD +NAGGV N+ YG Y R Sbjct: 257 AGSADNQLKDPRHGKYLHELGIVYAPDYVINAGGVI--------NVADELYG-----YNR 303 Query: 461 DSNYHLLMSVQESLERKFG 479 + + +S+E+ F Sbjct: 304 TRAMKRVDGIYDSIEKIFA 322 >5B37-A nrPDB Length = 361 Score = 260 bits (664), Expect = 1e-69, Method: Composition-based stats. Identities = 89/379 (23%), Positives = 144/379 (37%), Gaps = 68/379 (17%) Query: 132 IEGYRAQHSQHRTPCKGGIRYST----DVSVDEVKALASLMTYKCAVVDVPFGGAKAGVK 187 I+ A H P G R + ++ + L+ MTYK A ++P GG KA + Sbjct: 25 IKAIIAIHDTTLGPAMGATRILPYINEEAALKDALRLSRGMTYKAACANIPAGGGKAVII 84 Query: 188 INPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHY 247 NP+N TD +L + RF L + G +++ D+ T +E ++ Sbjct: 85 ANPENKTD-DLLRAYGRFVDSLNGRFITGQDVNITPDDVRTISQETKYVVGVSEK----- 138 Query: 248 DINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQ 307 G T GVF GI+ + E+ + S VQ Sbjct: 139 -----------------SGGPAPITSLGVFLGIKAAV-ESRWQSKR-----LDGMKVAVQ 175 Query: 308 GFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPY 367 G GNVG + R+LH D ++ D +DP + E+ K G+ + P Sbjct: 176 GLGNVGKNLCRHLHE----------HDVQLFVSD-VDPIKAEEVKRLFGATVVEPT---- 220 Query: 368 EGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPE--ADKIFLERNIMVI 425 I D DI P A L P ++A IIA AN E ++ ++ I+ Sbjct: 221 --EIYSLDVDIFAPCALGGILNSHTIPFLQASIIAGAANNQLENEQLHSQMLAKKGILYS 278 Query: 426 PDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKF---GKHG 482 PD +NAGG+ Y E + Y+ + + + ++ ++L F + G Sbjct: 279 PDYVINAGGLINVYNEMI-------------GYDEEKAFKQVHNIYDTLLAIFEIAKEQG 325 Query: 483 GTIPIVPTAEFQDRISGAS 501 T +DRI+ + Sbjct: 326 VTTNDAARRLAEDRINNSK 344 >1BW9-B nrPDB Length = 356 Score = 205 bits (520), Expect = 6e-53, Method: Composition-based stats. Identities = 73/304 (24%), Positives = 113/304 (37%), Gaps = 48/304 (15%) Query: 140 SQHRTPCKGGIRYST----DVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKI-NPKNYT 194 S P GG R + ++ + LA MT K AV ++P GG K+ + + P++ Sbjct: 32 STQLGPAAGGTRAAQYSQLADALTDAGKLAGAMTLKMAVSNLPMGGGKSVIALPAPRHSI 91 Query: 195 D-NELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHA 253 D + +I R + K G PD++T +M + DT Sbjct: 92 DPSTWARILRIHAENIDKL----SGNYWTGPDVNTNSADMDTLNDTTE------------ 135 Query: 254 CVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVG 313 V G+ + +GG T GVF ++ + S+ G+ T +VQG G VG Sbjct: 136 FVFGRSLERGGAGSSAFTTAVGVFEAMKATVAHRGLGSLDGL-------TVLVQGLGAVG 188 Query: 314 LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILE 373 GA+ + V ++D ++ H LG +L Sbjct: 189 GSLASLAAEAGAQLL-VADTDTE---------------RVAHAVALGHTAVAL--EDVLS 230 Query: 374 ADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPE-ADKIFLERNIMVIPDLYLNA 432 CD+ P A +T A + ++A AN E A I R I+ PD NA Sbjct: 231 TPCDVFAPCAMGGVITTEVARTLDCSVVAGAANNVIADEAASDILHARGILYAPDFVANA 290 Query: 433 GGVT 436 GG Sbjct: 291 GGAI 294 >3G1U-A nrPDB Length = 437 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 57/339 (16%), Positives = 102/339 (30%), Gaps = 50/339 (14%) Query: 154 TDVSVDEVKALASLMTYK---------CAVVDVPFGGAKAGV-KINPKNYTDNELEKITR 203 T V ++ +KAL + + + A + AK GV K TD E E Sbjct: 57 TAVLIETLKALGAELRWSSCNIFSTQDNAAAAI----AKTGVPVFAWKGETDEEYEWCIA 112 Query: 204 RFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTG-KPISQ 262 + + G P + G + + D Y + + TG K + + Sbjct: 113 QTVKGFSGDGL-------PNMILDDGGDLTNLVIDRYPELVPKIFGISEETTTGVKNLYK 165 Query: 263 GGIHGRISATGRGV-----------FHGIENFINEASYMSILGMTPGFGDKTFVVQGFGN 311 G + + V +G + + + M KT V G+G+ Sbjct: 166 RLSKGNLPISAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVM---IAGKTCCVCGYGD 222 Query: 312 VGLHSMRYLHRFGAKCIA--VGESDGSIWNPDGIDPKELEDF-KLQHGSILGFPKAKPYE 368 VG L FGA+ + V + + +G +ED H + Sbjct: 223 VGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVALVEDVMADAHIFVTTTGNDDIIT 282 Query: 369 GSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERN---IMVI 425 D I T+ ++A + P+ D+ +E I++ Sbjct: 283 SDHFPHMRDDAIVCNIGHFDTEIQVGWLEANA---KEHVEIKPQVDRYTMENGRHIILLA 339 Query: 426 PDLYLNAGGVTVSY---FEWLKNLNHVSYGRLTFKYERD 461 +N G S F + + ++ RD Sbjct: 340 KGRLVNLG--CASGHPSFVMSNSFTNQVLAQIELWSNRD 376 >3H9U-A nrPDB Length = 436 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 39/257 (15%), Positives = 74/257 (28%), Gaps = 29/257 (11%) Query: 226 MSTGEREMSWIADTYASTIGHYDINAHACVTG-----KPISQGGIHGRI-------SATG 273 + G +++ D G + TG K + +G + + + Sbjct: 127 LDDGGDLTNYVLDECKELDGKIYGVSEETTTGVKNLYKRLQRGKLTIPAMNVNDSVTKSK 186 Query: 274 RGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIA--VG 331 +G + + + M KT V G+G+VG L FGA+ + V Sbjct: 187 FDNLYGCRESLVDGIKRATDVM---IAGKTACVCGYGDVGKGCAAALRGFGARVVVTEVD 243 Query: 332 ESDGSIWNPDGIDPKELEDFKLQ-HGSILGFPKAKPYEGSILEADCDILIPAASEKQLTK 390 + +G +ED + H + D I T+ Sbjct: 244 PINALQAAMEGYQVLLVEDVVEEAHIFVTTTGNDDIITSEHFPRMRDDAIVCNIGHFDTE 303 Query: 391 SNAPRVKAKIIAEGANGPTTPEADKIFLERN---IMVIPDLYLNAGGVTVSY---FEWLK 444 +KA P+ D+ + I++ +N G S F Sbjct: 304 IQVAWLKANAKERV---EVKPQVDRYTMANGRHIILLAEGRLVNLG--CASGHPSFVMSN 358 Query: 445 NLNHVSYGRLTFKYERD 461 + + ++ RD Sbjct: 359 SFCNQVLAQIELWTNRD 375 >2HAE-A nrPDB Length = 386 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 55/149 (36%), Gaps = 7/149 (4%) Query: 279 GIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIW 338 G ++ A ++ + VV G G G + +++L G K + + G I Sbjct: 160 GTAVVVSAAFLNALKLTEKKIEEVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKG-IL 218 Query: 339 NPDGIDPKE-LEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVK 397 N + DP+ L ++ L+ I + + LE D I + L ++ Sbjct: 219 NEN--DPETCLNEYHLEIARITNPERLSGDLETALEG-ADFFIGVSRGNILKPEWIKKMS 275 Query: 398 AKIIAEGANGPTTPEAD-KIFLERNIMVI 425 K + P PE D ++ E ++ Sbjct: 276 RKPVIFALANPV-PEIDPELAREAGAFIV 303 >4WEQ-A nrPDB Length = 341 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 31/93 (33%), Gaps = 2/93 (2%) Query: 281 ENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNP 340 E + + + P D T + G G +G + R L G K I S I Sbjct: 143 EALAKKHEWRDLS--QPEAADVTVGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGV 200 Query: 341 DGIDPKELEDFKLQHGSILGFPKAKPYEGSILE 373 + D L+ F + ++G P I Sbjct: 201 ETYDAAGLDAFLGRTDFLVGLLPLTPDTRGIFN 233 >6GBN-A nrPDB Length = 438 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 38/255 (14%), Positives = 79/255 (30%), Gaps = 21/255 (8%) Query: 241 ASTIGHYDINAHACVTGKPISQGGIHGRI--------SATGRGVFHGIENFINEASYMSI 292 G + + K + G + + +G + + ++ + Sbjct: 154 KDIRGISEETTTGVLRLKDRERNGSLVLPAININDSVTKSKFDNKYGCKESLVDSIRRAT 213 Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNP--DGIDPKELED 350 M K VV G+G+VG S L GA+ I DG + K++ D Sbjct: 214 DVM---MAGKVAVVAGYGDVGKGSAASLRGAGARVIVTEIDPICALQAAMDGYEVKKMAD 270 Query: 351 FKLQHGSILGFPKAKP-YEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPT 409 + ++ K G +A D +I + + + G+ T Sbjct: 271 AVKRADIVVTATGNKNIITGEHFKAMRDKVIVCNIGHFDNEIDMAWLNKTY---GSTKVT 327 Query: 410 TPEADKIFLERN---IMVIPDLYLNAGGVT-VSYFEWLKNLNHVSYGRLTFKYERDSNYH 465 I+ I++ +N G T F + ++ +L + Sbjct: 328 VKPQVDIYNVDGHDVIILAEGRLVNLGCATGHPSFVMSSSFSNQVIAQLELWENSSKYEN 387 Query: 466 LLMSVQESLERKFGK 480 + ++ +SL+ K + Sbjct: 388 KVYTLPKSLDEKVAR 402 >2A9F-A nrPDB Length = 398 Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 59/167 (35%), Gaps = 30/167 (17%) Query: 278 HGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSI 337 HG + A + S+ + + + VV G G+ GL R L GA + V + G I Sbjct: 165 HGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDKFGII 224 Query: 338 -------WNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTK 390 P +D ++ + + + G++ + DI I ++ L Sbjct: 225 NEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGA-----------DIFIGVSAPGVLKA 273 Query: 391 SNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTV 437 ++ A+ + P PE + PD L AG V Sbjct: 274 EWISKMAARPVIFAMANPI-PE-----------IYPDEALEAGAYIV 308 >1CRW-G nrPDB Length = 333 Score = 37.1 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 43/131 (32%), Gaps = 17/131 (12%) Query: 303 TFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFP 362 + GFG +G +R GA+ +AV + ++ + + HG G Sbjct: 2 KIGINGFGRIGRLVLRAALEMGAQVVAVNDPFIALEY-----MVYMFKYDSTHGMFKGEV 56 Query: 363 KAKPYEGSILEADCDILIPAASEKQLTKSNAP--RVKAKIIAEGANGPTTPEADKIFLER 420 KA+ + + ++ N P + A+ I E TT E + Sbjct: 57 KAEDGALVVDGKKITVF------NEMKPENIPWSKAGAEYIVESTGVFTTIEKASAHFKG 110 Query: 421 N----IMVIPD 427 I+ P Sbjct: 111 GAKKVIISAPS 121 >1XDW-A nrPDB Length = 331 Score = 35.9 bits (81), Expect = 0.049, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 36/120 (30%), Gaps = 6/120 (5%) Query: 278 HGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIA--VGESDG 335 + + + + + T V G G +G + + H GA I V E G Sbjct: 123 YTTSRTAKKNFKVDAFMFSKEVRNCTVGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKG 182 Query: 336 SIWNPDGIDPKELEDFKL---QHGSILGFPKAKPYEGSILEA-DCDILIPAASEKQLTKS 391 + E+ + H + A + + D IL+ A + + Sbjct: 183 IEDYCTQVSLDEVLEKSDIITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTE 242 >3ING-A nrPDB Length = 325 Score = 35.6 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 10/92 (10%) Query: 298 GFGDKTFVVQGFGNVGLHSMRYL-------HRFGAKCIAVGESDGSIWNPDGIDPKELED 350 G + ++ G GNVGL+ +R + F K + V +S + +D + Sbjct: 1 GMKEIRIILMGTGNVGLNVLRIIDASNRRRSAFSIKVVGVSDSRSYASGRN-LDISSIIS 59 Query: 351 FKLQHGSILGFPKAKPYEGSILEADCDILIPA 382 K + G I +A ++ D+L+ Sbjct: 60 NKEKTGRISD--RAFSGPEDLMGEAADLLVDC 89 >5OFW-B nrPDB Length = 223 Score = 35.2 bits (79), Expect = 0.071, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 39/133 (29%), Gaps = 16/133 (12%) Query: 282 NFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD 341 + + + M KT + G G +G + FG K I Sbjct: 34 ASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTI------------- 80 Query: 342 GIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKI- 400 G DP + G + P + + L+P+ + L + + K + Sbjct: 81 GYDPIISPEVSASFG-VQQLPLEEIWPLCDFITVHTPLLPSTT-GLLNDNTFAQCKKGVR 138 Query: 401 IAEGANGPTTPEA 413 + A G E Sbjct: 139 VVNCARGGIVDEG 151 >2G76-A nrPDB Length = 335 Score = 35.2 bits (79), Expect = 0.073, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 39/133 (29%), Gaps = 16/133 (12%) Query: 282 NFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD 341 + + + M KT + G G +G + FG K I Sbjct: 146 ASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTI------------- 192 Query: 342 GIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKI- 400 G DP + G + P + + L+P+ + L + + K + Sbjct: 193 GYDPIISPEVSASFG-VQQLPLEEIWPLCDFITVHTPLLPSTT-GLLNDNTFAQCKKGVR 250 Query: 401 IAEGANGPTTPEA 413 + A G E Sbjct: 251 VVNCARGGIVDEG 263 >2DLD-A nrPDB Length = 337 Score = 34.8 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 29/89 (32%) Query: 280 IENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWN 339 ++ + + + D+ V G G++G MR + FGAK IA Sbjct: 125 MDEKMAKRDLRWAPTIGREVRDQVVGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNPELE 184 Query: 340 PDGIDPKELEDFKLQHGSILGFPKAKPYE 368 G L+D Q I P Sbjct: 185 KKGYYVDSLDDLYKQADVISLHVPDVPAN 213 >2ZJ1-A nrPDB Length = 495 Score = 34.8 bits (78), Expect = 0.091, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 26/75 (34%), Gaps = 2/75 (2%) Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIA--VGESDGSIWNPDGIDPKELED 350 G G K ++ G+G+VG + GA+ + + +G D +E+ Sbjct: 267 RGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEE 326 Query: 351 FKLQHGSILGFPKAK 365 ++ K Sbjct: 327 AIGDADIVVTATGNK 341 >6JCV-A nrPDB Length = 333 Score = 34.4 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 26/87 (29%), Gaps = 3/87 (3%) Query: 292 ILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIA--VGESDGSIWNPDGIDPKELE 349 + KT V G+GN G + G I V + + +G + E+ Sbjct: 6 LDANLDPLKGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKDKYYELAKKEGFEVYEI- 64 Query: 350 DFKLQHGSILGFPKAKPYEGSILEADC 376 D ++ + + E Sbjct: 65 DEAVRRSDVALLLIPDEVMKEVYEKKI 91 >3NJ4-A nrPDB Length = 435 Score = 34.4 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 37/224 (16%), Positives = 73/224 (32%), Gaps = 16/224 (7%) Query: 277 FHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIA--VGESD 334 +G + + + M K VV G+G+VG + L FGA+ I + + Sbjct: 195 LYGCRESLIDGIKRATDVM---IAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPIN 251 Query: 335 GSIWNPDGIDPKELEDFKLQHGSILGFPKA--KPYEGSILEADCDILIPAASEKQLTKSN 392 +G + + D Q G+I G E D I + + Sbjct: 252 ALQAAMEGYEVTTM-DEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEID 310 Query: 393 APRVKAKIIAEGANGPTTPEADKIFLERN---IMVIPDLYLNAG-GVTVSYFEWLKNLNH 448 + + E N P+ D+ L+ I++ +N G + F + + Sbjct: 311 VKWLNENAV-EKVN--IKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTN 367 Query: 449 VSYGRLTFKYERDSNYHLLMSVQESLERKFGK-HGGTIPIVPTA 491 ++ D + + + L+ + H G + + T Sbjct: 368 QVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTK 411 >4J90-A nrPDB Length = 222 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 37/102 (36%), Gaps = 1/102 (0%) Query: 299 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSI 358 +K F V G G G + LHR G + +AV ++ + + + + Sbjct: 4 IKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENEL 63 Query: 359 LGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKI 400 L + +E I+ +I + L + + P + K Sbjct: 64 LSL-GIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWVKA 104 >1DXY-A nrPDB Length = 333 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 4/108 (3%) Query: 295 MTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELED-FKL 353 + G +T V G G++G +++ FGAK IA +PD D LED FK Sbjct: 139 IGKELGQQTVGVMGTGHIGQVAIKLFKGFGAKVIAYDPYPMKGDHPD-FDYVSLEDLFKQ 197 Query: 354 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKII 401 L P + I EA +++ P A + + + + + Sbjct: 198 SDVIDLHVPGIEQNTHIINEAAFNLMKPGAI--VINTARPNLIDTQAM 243 >1J49-A nrPDB Length = 333 Score = 34.0 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 27/90 (30%) Query: 279 GIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIW 338 ++ + + D+ V G G++G M+ + FGAK I Sbjct: 124 AMDEKVARHDLRWAPTIGREVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPEL 183 Query: 339 NPDGIDPKELEDFKLQHGSILGFPKAKPYE 368 G L+D Q I P Sbjct: 184 EKKGYYVDSLDDLYKQADVISLHVPDVPAN 213 >3JSA-A nrPDB Length = 328 Score = 34.0 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 10/87 (11%) Query: 304 FVVQGFGNVGLHSMRYL------HRFGAK--CIAVGESDGSIWNPDGIDPKELEDFKLQH 355 + G GNVGL+ +R + +R G K + V +S S +N + ID ++ +K + Sbjct: 6 LSIFGLGNVGLNLLRIIRSFNEENRLGLKFNVVFVADSLHSYYN-ERIDIGKVISYKEK- 63 Query: 356 GSILGFPKAKPYEGSILEADCDILIPA 382 GS+ L D DI++ A Sbjct: 64 GSLDSLEYESISASEALARDFDIVVDA 90 >5JXW-A nrPDB Length = 498 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 35/115 (30%), Gaps = 24/115 (20%) Query: 294 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKL 353 G K VV G+G VG + L GA+ I IDP + Sbjct: 264 GCIQMLAGKKIVVLGYGEVGKGCAQGLSGVGARVIVTE-----------IDPICALQASM 312 Query: 354 QHGSILGFPKAKPYEGSILEADCDILIPAASEK--QLTKSNAPRVKAKIIAEGAN 406 + + + DI I A+ +T + ++K AN Sbjct: 313 EGYQVSVLEDVVS--------EADIFI-TATGNKDVITVEHMRKMKENAYI--AN 356 >5TX7-A nrPDB Length = 327 Score = 33.2 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 36/273 (13%), Positives = 72/273 (26%), Gaps = 37/273 (13%) Query: 184 AGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYAST 243 + ++P+ +D +E+ + K D+ A G R +S +A Y Sbjct: 26 GELVVHPRTPSDKIIERAAGAHVVLTNKVPL-----DMSALQALPGLRFVSVLATGYDK- 79 Query: 244 IGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEAS-----------YMSI 292 + G + +++ + Sbjct: 80 VDVAAAGVLGIPVSNVPGYGTDSVAQHVFALLLELCRRTALHDHRIRAGAWTQSPDWCFW 139 Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFK 352 KT + GFGN G R + G IA + + L++ Sbjct: 140 DSTQEELTGKTMGIVGFGNTGRRVGRIANALGMNVIAYAPRSRFDPDYRPFEHVGLDELF 199 Query: 353 LQHGSILGFPKAKPYEGSILEADCDILIPAAS---EKQLTKSNAPRVKAKIIAEGAN--- 406 + P + D A+ + + P + + +AE + Sbjct: 200 TSADVVSLHCPLTPETEGL----VDARRLASMRPGSYLINTARGPLLDERAVAEALDSGR 255 Query: 407 ---------GPTTPEADK-IFLERNIMVIPDLY 429 P AD + +N ++ P L Sbjct: 256 LAGAGLDVLSQEPPAADNPLLSAKNCLITPHLA 288 >1CDO-A nrPDB Length = 374 Score = 33.2 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 28/76 (36%), Gaps = 14/76 (18%) Query: 273 GRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGE 332 G GV G +N A T V G G VGL ++ H GAK I + Sbjct: 174 GCGVSTGFGAAVNTAKVEP---------GSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVD 224 Query: 333 SDGSIWNPDGIDPKEL 348 NPD + ++ Sbjct: 225 -----LNPDKFEKAKV 235 >5ZZ6-A nrPDB Length = 208 Score = 33.2 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 13/95 (13%) Query: 274 RGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRY--LHRFGAKCIAVG 331 RGV + +E+ Y +I + + VV G GN+G Y + G + I + Sbjct: 60 RGVGYNVEHL-----YDAIGEILGVKKEWKLVVVGAGNIGRAVANYTVMKEKGFRIIGIF 114 Query: 332 ESDGSIWNPDGI------DPKELEDFKLQHGSILG 360 +SD S + D ELE F +HG +G Sbjct: 115 DSDPSKIGKEAAPGLTVSDVSELEKFVEEHGVEIG 149 >2VHY-A nrPDB Length = 377 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 271 ATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAV 330 A G +H + + ++G PG VV G G G ++ R + GA + Sbjct: 141 AAQVGAYHLMR---TQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVL 197 Query: 331 G 331 Sbjct: 198 D 198 >3OND-A nrPDB Length = 488 Score = 33.2 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Query: 277 FHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAV 330 +G + + + + M K VV G+G+VG L + GA+ I Sbjct: 244 LYGCRHSLPDGLMRATDVM---IAGKVAVVAGYGDVGKGCAAALKQAGARVIVT 294 >2D0I-A nrPDB Length = 333 Score = 32.5 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 26/87 (29%), Gaps = 10/87 (11%) Query: 277 FHGIENFINEASYMSILGMTPGFG------DKTFVVQGFGNVGLHSMRYLHRFGAKCIAV 330 H + FI + S + GF K + G G +G R L FG K Sbjct: 116 IHYADKFIRRGEWESHAKIWTGFKRIESLYGKKVGILGMGAIGKAIARRLIPFGVKLYYW 175 Query: 331 GESDGSIWNPD----GIDPKELEDFKL 353 + +D EL + Sbjct: 176 SRHRKVNVEKELKARYMDIDELLEKSD 202 >2VYN-D nrPDB Length = 334 Score = 32.5 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 29/77 (37%), Gaps = 5/77 (6%) Query: 303 TFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFP 362 + GFG +G +R G + +AV + +P+ + + + HG G Sbjct: 3 KVGINGFGRIGRLVLRVCMEKGVRVVAVNDP---FIDPEYM--VYMFKYDSTHGRYKGTV 57 Query: 363 KAKPYEGSILEADCDIL 379 + K + + ++ Sbjct: 58 EHKNGRLVVDNLEINVF 74 >5M65-A nrPDB Length = 479 Score = 32.5 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 37/112 (33%), Gaps = 22/112 (19%) Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFK 352 G K +V GFG+VG S L + G + + +DP Sbjct: 252 RGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMV-----------SEVDPICALQAA 300 Query: 353 LQHGSILGFPKAKPYEGSILEADCDILIPAASEK--QLTKSNAPRVKAKIIA 402 ++ ++ A P DI + A+ +T + +K + I Sbjct: 301 MEGYEVVTMEDAAP--------RADIFV-TATGNKDIITIEHMRAMKDRAIV 343 >3HG7-A nrPDB Length = 324 Score = 32.1 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 17/36 (47%) Query: 298 GFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES 333 G +T ++ G G++G H FG K + V S Sbjct: 137 GLKGRTLLILGTGSIGQHIAHTGKHFGMKVLGVSRS 172 >4PRK-A nrPDB Length = 336 Score = 32.1 bits (71), Expect = 0.66, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 42/114 (36%), Gaps = 16/114 (14%) Query: 295 MTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD------GIDPKEL 348 ++ +KT + G G++G + GAK +A I+NP+ D + Sbjct: 140 ISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYD----VIYNPEVEPYLTYADFDTV 195 Query: 349 EDFKL---QHGSILGFPKAKPYEGSILEADCD-ILIPAASEKQLTKSNAPRVKA 398 H +L + + E D ILI AA + + A ++A Sbjct: 196 LKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGELV--DTAALIEA 247 >5H82-A nrPDB Length = 389 Score = 32.1 bits (71), Expect = 0.70, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 41/127 (32%), Gaps = 17/127 (13%) Query: 257 GKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKT----------FVV 306 G+ GG + A VF EN A + G + V Sbjct: 159 GEDRIYGGYSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGV 218 Query: 307 QGFGNVGLHSMRYLHRFGAKCIAVGES---DGSIWNPDGID----PKELEDFKLQHGSIL 359 GFG +G ++++ FGA + S G+D KE E+ K ++ Sbjct: 219 VGFGRIGKLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEEMKAAESTLD 278 Query: 360 GFPKAKP 366 G P Sbjct: 279 GIFDCVP 285 >4XDY-A nrPDB Length = 338 Score = 32.1 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 34/104 (32%), Gaps = 11/104 (10%) Query: 296 TPGFGDKTFVVQGFGNVGLHSMRYLHRFGAK-CIAVGESDGSIWNPDGIDPKELEDFKLQ 354 DKT V G+G G L G I E G NP E K Sbjct: 11 DSILRDKTIAVMGYGAQGDAQANCLKDSGINVVIGETEILGGNKNPSW------EKAKED 64 Query: 355 HGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKA 398 +L KA + D + PA E Q+ P++KA Sbjct: 65 GFEVLPIDKAAEKGDVVHILLPDEVQPAIYENQIK----PQLKA 104 >2DC1-A nrPDB Length = 236 Score = 32.1 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 34/93 (36%), Gaps = 24/93 (25%) Query: 308 GFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPY 367 G+G +G +L R +G + + D + +H ++ Sbjct: 7 GYGAIGKFLAEWLER------------------NGFEIAAILDVRGEHEKMV------RG 42 Query: 368 EGSILEADCDILIPAASEKQLTKSNAPRVKAKI 400 L+ + D+ + AAS++ + +KA I Sbjct: 43 IDEFLQREMDVAVEAASQQAVKDYAEKILKAGI 75 >5DT9-A nrPDB Length = 387 Score = 32.1 bits (71), Expect = 0.73, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 36/113 (31%), Gaps = 13/113 (11%) Query: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 360 DKT + G G VG + + L G K + + + ELE Q I Sbjct: 123 DKTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQAQGDEREFT--ELETLLKQADVITL 180 Query: 361 FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA 413 E LI AA +QL +I+ A GP A Sbjct: 181 HTPITRGG----EWPTHHLIDAAILEQLRSD-------QILINAARGPVVDNA 222 >2HMT-A nrPDB Length = 144 Score = 32.1 bits (71), Expect = 0.73, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 299 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSI 358 +K F V G G G ++ LHR G + +AV ++ + + + + Sbjct: 4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENEL 63 Query: 359 LGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKI 400 L + +E I+ +I + L + + P + K Sbjct: 64 LSL-GIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWVKA 104 >5BUT-A nrPDB Length = 288 Score = 32.1 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 299 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSI 358 +K F V G G G ++ LHR G + +AV ++ + + + + Sbjct: 4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENEL 63 Query: 359 LGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKI 400 L + +E I+ +I + L + + P + K Sbjct: 64 LSL-GIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWVKA 104 Score = 31.3 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 39/106 (36%), Gaps = 1/106 (0%) Query: 295 MTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQ 354 + G K F V G G G ++ LHR G + +AV ++ + + + Sbjct: 142 LNYLEGSKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATE 201 Query: 355 HGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKI 400 +L + +E I+ +I + L + + P + K Sbjct: 202 ENELLSL-GIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWVKA 246 >3UOG-A nrPDB Length = 363 Score = 32.1 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%) Query: 288 SYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSI 337 ++ +++ VVQG G V L ++ GA+ I S + Sbjct: 177 AWFALVEKGHLRAGDRVVVQGTGGVALFGLQIAKATGAEVIVTSSSREKL 226 >5AOV-A nrPDB Length = 336 Score = 31.7 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 57/174 (32%), Gaps = 18/174 (10%) Query: 271 ATGRGVFHGIENFI------NEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFG 324 AT R V G + ++ + KT + GFG +G R F Sbjct: 114 ATARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFN 173 Query: 325 AKCIAVGESDGSIWNPD-GIDPKELEDF-KLQHGSILGFPKAKPYEGSI------LEADC 376 + + + S + G + + LE+ K IL P K I L Sbjct: 174 MRILYYSRTRKSQAEKELGAEYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKPT 233 Query: 377 DILIPAASEKQLTKSN-APRVKAKIIAEGANGPTTPE---ADKIFLERNIMVIP 426 IL+ A K + +K IA E +++F N+++ P Sbjct: 234 AILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELFSLDNVVLTP 287 >6B4O-A nrPDB Length = 452 Score = 31.7 bits (70), Expect = 0.92, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 58/190 (30%), Gaps = 29/190 (15%) Query: 185 GVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSW--IADTYAS 242 G + KN++ +L + ++ L G D + ER + Sbjct: 73 GFDVEIKNFSFKQLVENREKYIDFLHGAYNRGL-------DSNNIERIHGYATFTGEQTI 125 Query: 243 TIGHYDINAHACV--TGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG 300 + + A + TG + GI G A F +E Sbjct: 126 EVNGTEYTAPHILIATGGRPKKLGIPGEEYALDSNGFFALEEM----------------- 168 Query: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 360 K V G G + LH GA+ + + + D + +++ + + G + Sbjct: 169 PKRVVFVGAGYIAAELAGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMG-MQI 227 Query: 361 FPKAKPYEGS 370 P A P + Sbjct: 228 HPNATPAKIE 237 >3DC2-A nrPDB Length = 529 Score = 31.7 bits (70), Expect = 0.93, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 19/53 (35%) Query: 279 GIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVG 331 + + E ++ KT V G G +G + + FGA +A Sbjct: 120 AADASLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYD 172 >4M7W-A nrPDB Length = 258 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 7/101 (6%) Query: 240 YASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGF 299 Y ++G I A+ + I G R +E+ + + +LG T + Sbjct: 19 YFQSMGTPHIGANRGDVAETILLPGDPLRAK---YIAETFLEDVVQYNNVRGMLGFTGTY 75 Query: 300 GDKTFVVQGFG----NVGLHSMRYLHRFGAKCIAVGESDGS 336 K VQG G ++G++S + FG K + + GS Sbjct: 76 KGKKVSVQGTGMGVPSIGIYSHELITEFGVKNLIRVGTAGS 116 >1VC2-A nrPDB Length = 331 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 42/133 (31%), Gaps = 18/133 (13%) Query: 302 KTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGF 361 + GFG +G R LH G + + + D L + +G F Sbjct: 1 MKVGINGFGRIGRQVFRILHERGVEVALINDLT------DNKTLAHLLKYDSTYGR---F 51 Query: 362 PKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKA--KIIAEGANGPTTPEADKIFLE 419 P A Y+ L D + A + P +A ++ E T E + LE Sbjct: 52 PGAVGYDEENLYVDGKAIRATAIK---DPREIPWKQAGVGVVVESTGVFTDGEKARAHLE 108 Query: 420 RN----IMVIPDL 428 I+ P Sbjct: 109 AGAKKVIITAPAK 121 >6BII-A nrPDB Length = 333 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 36/99 (36%), Gaps = 2/99 (2%) Query: 288 SYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD-GIDPK 346 ++ + + KT + GFG +G + FG + + S + G + K Sbjct: 137 AWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMRILYTARSRKPEAEKELGAEFK 196 Query: 347 ELED-FKLQHGSILGFPKAKPYEGSILEADCDILIPAAS 384 LE+ + +L P K I E ++ P A Sbjct: 197 PLEELLRESDFVVLAVPLTKETYHMINEERLRLMKPTAV 235 >4CBQ-A nrPDB Length = 314 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 37/105 (35%), Gaps = 20/105 (19%) Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFK 352 G P F +K +V G G+ + +L ++G+K I + D + + Sbjct: 144 DGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVII-------LHRRDAFRASKTMQER 196 Query: 353 LQHGSILGFPKAK-PYEGSILEADCDILIPAASEKQLTKSNAPRV 396 +L PK + + ++E + D L + + Sbjct: 197 -----VLNHPKIEVIWNSELVELEGD-------GDLLNGAKIHNL 229 >3H9E-O nrPDB Length = 346 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 15/31 (48%) Query: 303 TFVVQGFGNVGLHSMRYLHRFGAKCIAVGES 333 T + GFG +G +R G K +AV + Sbjct: 9 TVGINGFGRIGRLVLRACMEKGVKVVAVNDP 39 >1X14-A nrPDB Length = 401 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 10/134 (7%) Query: 302 KTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELE-DFKLQHGSILG 360 +V G G GL ++ + GA A + + LE DFK + GS G Sbjct: 173 AKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDG 232 Query: 361 FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420 + AK + ++A+ ++ A E + + A I + A T E Sbjct: 233 Y--AKVMSDAFIKAEMELFAAQAKEVDIIVTTA-----LIPGKPAPKLITREMVDSMKAG 285 Query: 421 NIMVIPDLYLNAGG 434 +++V DL GG Sbjct: 286 SVIV--DLAAQNGG 297 >3EVT-A nrPDB Length = 324 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 11/79 (13%), Positives = 23/79 (29%), Gaps = 10/79 (12%) Query: 265 IHGRISATGRGVFHGIENFIN--EASYMSILG--------MTPGFGDKTFVVQGFGNVGL 314 A V + + + A++++ G T + ++ G G +G Sbjct: 91 SGIHADAISESVLAAMLSVVRGYHAAWLNQRGARQWALPMTTSTLTGQQLLIYGTGQIGQ 150 Query: 315 HSMRYLHRFGAKCIAVGES 333 G I V + Sbjct: 151 SLAAKASALGMHVIGVNTT 169 >3DO5-A nrPDB Length = 327 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 39/124 (31%), Gaps = 19/124 (15%) Query: 303 TFVVQGFGNVGLHSMRYLHRFGA---------KCIAVGESDGSIWNPDGIDPKELEDFKL 353 + GFG VG L R K AV +S SI E K Sbjct: 4 KIAIVGFGTVGQGVAELLIRKREEIEKAIGEFKVTAVADSKSSI--SGDFSLVEALRMKR 61 Query: 354 QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRV-----KAKIIAEGANGP 408 + G + KA + AD D+LI A+ + + + K + GP Sbjct: 62 ETGMLRDDAKA---IEVVRSADYDVLIEASVTRVDGGEGVNYIREALKRGKHVVTSNKGP 118 Query: 409 TTPE 412 E Sbjct: 119 LVAE 122 >3D3W-A nrPDB Length = 244 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 295 MTPGFGDKTFVVQGFGN-VGLHSMRYLHRFGAKCIAVGESDGSI 337 M + +V G G +G +++ LH GA+ +AV + + Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADL 44 >3N58-A nrPDB Length = 464 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 34/195 (17%), Positives = 63/195 (32%), Gaps = 12/195 (6%) Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKC-IAVGESDGSIWNP-DGIDPKELED 350 G K VV G+G+VG S + L GA+ + + ++ DG + L+D Sbjct: 239 RGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDD 298 Query: 351 FKL-QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPT 409 + + D+ N +V A + N Sbjct: 299 AASTADIVVTTTGNKDVITIDHMRKMKDM---CIVGNIGHFDNEIQVAALRNLKWTN--V 353 Query: 410 TPEADKIFLERN---IMVIPDLYLNAGGVT-VSYFEWLKNLNHVSYGRLTFKYERDSNYH 465 P+ D I I++ LN G T F + + G++ D+ + Sbjct: 354 KPQVDLIEFPDGKRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLGQIELFTRTDAYKN 413 Query: 466 LLMSVQESLERKFGK 480 + + + L+ K + Sbjct: 414 EVYVLPKHLDEKVAR 428 >6APH-A nrPDB Length = 445 Score = 30.6 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 67/208 (32%), Gaps = 15/208 (7%) Query: 278 HGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESD--- 334 +G +A + M K VV GFG+VG + G+ + V E D Sbjct: 206 YGCRESAVDAIRRATDVM---LAGKRVVVCGFGDVGKGTAASFRGAGS-IVTVTEIDPIC 261 Query: 335 GSIWNPDGIDPKELEDFKLQHGSILGFPKA-KPYEGSILEADCDILIPAASEKQLTK-SN 392 +G + K+L+ I+ G E D I + Sbjct: 262 ALQAAMEGYEVKQLDTVVDNADIIITTTGNFGIVRGEHFEKMKDKTIVCNIGHFDNEIDM 321 Query: 393 APRVKAKIIAEGANGPTTPEADKIFLERN--IMVIPDLYLNAGGVT-VSYFEWLKNLNHV 449 A K P+ DK + N I++ +N G T F + ++ Sbjct: 322 AWLNKNH---GATKVEIKPQVDKYNVNGNDIIILAEGRLVNLGCATGHPSFVMSNSFSNQ 378 Query: 450 SYGRLTFKYERDSNYHLLMSVQESLERK 477 + ++ D + + ++ + L+ K Sbjct: 379 TLAQIELWVHSDKYENKVYTLPKHLDEK 406 >3OIG-A nrPDB Length = 266 Score = 30.6 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 14/37 (37%), Gaps = 3/37 (8%) Query: 295 MTPGFGDKTFVVQGFGN---VGLHSMRYLHRFGAKCI 328 M + VV G N + R LH GA+ I Sbjct: 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLI 37 >3POC-A nrPDB Length = 666 Score = 30.2 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 22/69 (31%), Gaps = 5/69 (7%) Query: 57 VADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVL 116 + D P F K ++ R I++ + + EE +N K + Sbjct: 214 EKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNY-----FCKREDGSD 268 Query: 117 SLSFPIRRD 125 ++ D Sbjct: 269 FVAAVWPGD 277 >4RQU-A nrPDB Length = 375 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 20/60 (33%), Gaps = 5/60 (8%) Query: 288 SYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKE 347 + L + ++ + G G VGL + GA+ G +N D + Sbjct: 178 GLGATLNVAKPKKGQSVAIFGLGAVGLGAAE-----GARIAGASRIIGVDFNSKRFDQAK 232 >4DGS-A nrPDB Length = 340 Score = 30.2 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 13/47 (27%), Gaps = 2/47 (4%) Query: 283 FINEASY--MSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKC 327 + E + L + K V G G +G FG Sbjct: 151 LVREGRWAAGEQLPLGHSPKGKRIGVLGLGQIGRALASRAEAFGMSV 197 >4S1V-D nrPDB Length = 332 Score = 30.2 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 50/149 (33%), Gaps = 15/149 (10%) Query: 293 LGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAV-GESDGSIWNPDGI----DPKE 347 LG+ +T + G G +G ++ H FG + E+ G D E Sbjct: 139 LGLGRTLSGRTLGIWGLGKIGQRIAQFGHVFGMPILVWGSEASRQKALELGYQAAADKAE 198 Query: 348 LEDFKL---QHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNA--PRVKAKIIA 402 H + + + +L D L S +L +S A ++A + Sbjct: 199 FFAKADVLSLHLRLNDATRGIVTKQDLLAMKPDSLFVNTSRAELVESGALYSVMQANPMR 258 Query: 403 EGA-----NGPTTPEADKIFLERNIMVIP 426 + A N P P + + N++ P Sbjct: 259 QAAVDVYENEPALPNNEPLLSLPNVLCAP 287 >2EKL-A nrPDB Length = 313 Score = 29.8 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 27/79 (34%), Gaps = 5/79 (6%) Query: 251 AHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFG 310 A T + G + A R ++ + + I G+ KT + GFG Sbjct: 97 APGASTDSAVEL--TIGLMIAAARKMYTSM-ALAKSGIFKKIEGLE--LAGKTIGIVGFG 151 Query: 311 NVGLHSMRYLHRFGAKCIA 329 +G + G K +A Sbjct: 152 RIGTKVGIIANAMGMKVLA 170 >4YRY-B nrPDB Length = 468 Score = 29.8 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 28/90 (31%), Gaps = 1/90 (1%) Query: 241 ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG 300 + YD G P GI G + +Y+ TP Sbjct: 220 KELLSEYDAVFIGTGAGTP-KFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRV 278 Query: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAV 330 K V G GN + + R R GA+ + + Sbjct: 279 GKKVAVIGAGNTAMDAARSALRLGAEKVYI 308 >2CZG-A nrPDB Length = 433 Score = 29.8 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 18/133 (13%), Positives = 42/133 (31%), Gaps = 12/133 (9%) Query: 283 FINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGS------ 336 + LG + ++ G G +G R G + +AV + Sbjct: 1 MVVMIKLRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAPAMQVA 60 Query: 337 --IWNPDGIDPKELEDFKLQHGSILGFPKAKPYE-GSILEADCD--ILIPAASEKQLTKS 391 + + +D L + P+ + ++ E + D ++P A + Sbjct: 61 HRSYVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKDGYFVVPNARATWIAMH 120 Query: 392 NAPRVKAKIIAEG 404 R++ ++ E Sbjct: 121 R-ERLRETLVKEA 132 >5C7I-O nrPDB Length = 333 Score = 29.8 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%) Query: 303 TFVVQGFGNVGLHSMRYLHRFGAKCIAVGES 333 T + GFG +G +R G + +AV + Sbjct: 3 TVGINGFGRIGRLVLRVCMEKGIRVVAVNDP 33 >1V8B-A nrPDB Length = 479 Score = 29.8 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 20/54 (37%), Gaps = 3/54 (5%) Query: 274 RGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKC 327 +G + + + + + K V+ G+G+VG + GA+ Sbjct: 233 YDNVYGCRHSLPDGLMRATDFL---ISGKIVVICGYGDVGKGCASSMKGLGARV 283 >1URH-A nrPDB Length = 280 Score = 29.8 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 31/147 (21%), Positives = 46/147 (31%), Gaps = 11/147 (7%) Query: 295 MTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDP--KELEDFK 352 M FG + + G G G L GA + GE + + +NP+ + L Sbjct: 106 MLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFN-AAFNPEAVVKVTDVLLASH 164 Query: 353 LQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPE 412 I+ A + D P + A V + TT E Sbjct: 165 ENTAQIIDARPAARFNAE-----VDEPRPGLRRGHIPG--ALNVPWTELVREGELKTTDE 217 Query: 413 ADKIFLERNIMV-IPDLYLNAGGVTVS 438 D IF R + P + GVT + Sbjct: 218 LDAIFFGRGVSYDKPIIVSCGSGVTAA 244 >3SLK-A nrPDB Length = 795 Score = 29.4 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 13/114 (11%) Query: 9 LLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFK 68 +L+SR GPAA G +A L+ A +A R ++ +A D+ Sbjct: 560 VLVSRRGPAASG-----AAELVAQLTAYGAEVSLQACDVADRETLAKVLASIPDEHPLTA 614 Query: 69 MVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRV---RGILRIIKPCNHVLSLS 119 +V A +++D + E L ++ R +V R +L +I P ++ S Sbjct: 615 VV-----HAAGVLDDGVSESLTVERLDQVLRPKVDGARNLLELIDPDVALVLFS 663 >5AVO-A nrPDB Length = 304 Score = 29.4 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 13/114 (11%) Query: 302 KTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFK--LQHGSIL 359 ++ G+GNVG + LH + + G I GI ++ EDF L+ Sbjct: 1 MKLLLFGYGNVGKAFRKLLHEKRSPELN-DVIIGGIVTRRGIMLQDKEDFTPDLEGDVFK 59 Query: 360 GFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEA 413 F K KP DI++ +S + + + I +G N TT +A Sbjct: 60 AFEKIKP----------DIIVDVSSANYNNGEPSLSLYKEAIKDGVNIITTNKA 103 >3LK7-A nrPDB Length = 451 Score = 29.4 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 30/133 (22%), Positives = 46/133 (34%), Gaps = 29/133 (21%) Query: 299 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPD-------------GIDP 345 F +K +V G G + R L + GA + V + NP G P Sbjct: 7 FENKKVLVLGLARSGEAAARLLAKLGA-IVTVNDGKPFDENPTAQSLLEEGIKVVCGSHP 65 Query: 346 KELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQ------------LTKSNA 393 EL D ++ P PY +++ + IP +E + +T SN Sbjct: 66 LELLD--EDFCYMIKNPGI-PYNNPMVKKALEKQIPVLTEVELAYLVSESQLIGITGSNG 122 Query: 394 PRVKAKIIAEGAN 406 +IAE N Sbjct: 123 KTTTTTMIAEVLN 135 >1QP8-A nrPDB Length = 303 Score = 29.4 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 19/66 (28%), Gaps = 2/66 (3%) Query: 297 PGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHG 356 P + V G G +G + L GA+ + P E + Sbjct: 120 PLIQGEKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPKE--GPWRFTNSLEEALREARA 177 Query: 357 SILGFP 362 ++ P Sbjct: 178 AVCALP 183 >5YCX-A nrPDB Length = 266 Score = 29.4 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 16/38 (42%), Gaps = 3/38 (7%) Query: 294 GMTPGFGDKTFVVQGFGN---VGLHSMRYLHRFGAKCI 328 G KTFVV G N + R LH GAK I Sbjct: 1 GSMELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLI 38 >3K5P-A nrPDB Length = 416 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 16/55 (29%) Query: 284 INEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIW 338 + + + KT + G+GN+G G SD + Sbjct: 139 AHAGGWEKTAIGSREVRGKTLGIVGYGNIGSQVGNLAESLGMTVRYYDTSDKLQY 193 >4KUG-A nrPDB Length = 290 Score = 29.4 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 37/108 (34%), Gaps = 14/108 (12%) Query: 302 KTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGF 361 K V G G +G ++ G + I V + + + + I Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKGCEVI-VRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 362 PKAKP------YEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAE 403 K + L ADCD+++ AA E ++K +I AE Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENM-------KIKKEIFAE 101 >1CYD-A nrPDB Length = 244 Score = 29.4 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 295 MTPGFGDKTFVVQGFGN-VGLHSMRYLHRFGAKCIAVGESD 334 M F +V G G +G +++ LH GAK +AV ++ Sbjct: 1 MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTN 41 >5JFC-L nrPDB Length = 474 Score = 29.4 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 12/27 (44%) Query: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKC 327 K V G GN + + R R GA+ Sbjct: 293 GKRVAVIGGGNTAMDAARSALRLGAEV 319 >3COS-A nrPDB Length = 381 Score = 29.0 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 18/123 (14%), Positives = 30/123 (24%), Gaps = 10/123 (8%) Query: 288 SYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKE 347 Y + + T V G G VGL ++ G K G N + + Sbjct: 186 GYGAAINNAKVTPGSTCAVFGLGGVGLSAV-----MGCKAAGASRIIGIDINSEKFVKAK 240 Query: 348 LEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAA-----SEKQLTKSNAPRVKAKIIA 402 + + + D + A + L + A I Sbjct: 241 ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 300 Query: 403 EGA 405 A Sbjct: 301 VAA 303 >3D64-A nrPDB Length = 494 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 19/128 (14%), Positives = 35/128 (27%), Gaps = 25/128 (19%) Query: 277 FHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGS 336 +G + + + M K VV G+G+VG + L GA Sbjct: 256 LYGCRESLVDGIKRATDVM---IAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTE----- 307 Query: 337 IWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEK--QLTKSNAP 394 IDP ++ + DI + A+ + + Sbjct: 308 ------IDPICALQAAME--------GYRVVTMEYAADKADIFV-TATGNYHVINHDHMK 352 Query: 395 RVKAKIIA 402 ++ I Sbjct: 353 AMRHNAIV 360 >2LDB-A nrPDB Length = 317 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 37/105 (35%), Gaps = 10/105 (9%) Query: 300 GDKTFVVQGFGNVGLHSMRYLHRFG-AKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSI 358 G VV G G VG + L G A I + +++ S D +D HG + Sbjct: 5 GGARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDF--------NHGKV 56 Query: 359 LGFPKAKPYEGSILE-ADCDILIPAASEKQLTKSNAPRVKAKIIA 402 + G + D D+++ A Q + K IA Sbjct: 57 FAPKPVDIWHGDYDDCRDADLVVICAGANQKPGETRLDLVDKNIA 101 >5E4R-A nrPDB Length = 490 Score = 29.0 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 27/79 (34%), Gaps = 4/79 (5%) Query: 297 PGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWN---PDGIDPKELEDFKL 353 +KT + G+G+ G L G + E G W DG P +D + Sbjct: 13 EPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKD-AV 71 Query: 354 QHGSILGFPKAKPYEGSIL 372 I+ F + S+ Sbjct: 72 AIADIIVFLVPDMVQKSLW 90 >4XDZ-A nrPDB Length = 343 Score = 29.0 bits (63), Expect = 6.0, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 27/79 (34%), Gaps = 4/79 (5%) Query: 297 PGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWN---PDGIDPKELEDFKL 353 +KT + G+G+ G L G + E G W DG P +D + Sbjct: 13 EPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKD-AV 71 Query: 354 QHGSILGFPKAKPYEGSIL 372 I+ F + S+ Sbjct: 72 AIADIIVFLVPDMVQKSLW 90 >3PDI-A nrPDB Length = 483 Score = 29.0 bits (63), Expect = 6.3, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 30/112 (26%), Gaps = 7/112 (6%) Query: 269 ISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCI 328 T R + + K ++ G + L G K + Sbjct: 302 PDLTARTEALIAREEAKVRAA--LEPWRARLEGKRVLLYTGGVKSWSVVSALQDLGMKVV 359 Query: 329 AVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILI 380 A G + D + + +L A+ ++ E DILI Sbjct: 360 ATGTKKSTEE-----DKARIRELMGDDVKMLDEGNARVLLKTVDEYQADILI 406 >3FBG-A nrPDB Length = 346 Score = 28.6 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 11/81 (13%), Positives = 27/81 (33%), Gaps = 1/81 (1%) Query: 300 GDKTF-VVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSI 358 KT ++ G G VG + + +G + I + +I + + + K + Sbjct: 150 EGKTLLIINGAGGVGSIATQIAKAYGLRVITTASRNETIEWTKKMGADIVLNHKESLLNQ 209 Query: 359 LGFPKAKPYEGSILEADCDIL 379 + + + D+ Sbjct: 210 FKTQGIELVDYVFCTFNTDMY 230 >4Y4N-A nrPDB Length = 286 Score = 28.6 bits (62), Expect = 7.5, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 19/53 (35%) Query: 281 ENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES 333 E A S M D + G G GL + RY+ + G K + + Sbjct: 32 EYATTRAILKSAFDMWLDIIDVDVAIVGGGPSGLTAARYIAKEGYKVVVLERH 84 >4XRR-A nrPDB Length = 456 Score = 28.6 bits (62), Expect = 7.9, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 17/37 (45%) Query: 303 TFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWN 339 V+ G G VG L GA+ +AV G++ + Sbjct: 17 KVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVAD 53 >1O89-A nrPDB Length = 345 Score = 28.6 bits (62), Expect = 7.9, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 9/113 (7%) Query: 300 GDKTFVVQG-FGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSI 358 D VV G G VG ++ LH+ G + +AV + + + + Sbjct: 167 QDGEIVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDE----- 221 Query: 359 LGFPKAKPYEGSILEADCDILIPAASEKQLTKSN-APRVKAKIIAEGANGPTT 410 F +++P E + D + K L + N V A +A G PTT Sbjct: 222 --FAESRPLEKQVWAGAIDTVGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTT 272 >5MH6-A nrPDB Length = 308 Score = 28.6 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 26/79 (32%), Gaps = 10/79 (12%) Query: 299 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVG------ESDGSIWNPDGIDPKELEDFK 352 + V G G +G + G + + V ++ +++ PD + E Sbjct: 133 LAGERVCVVGLGTLGRGVVDRAAALGMEVVGVRRSGDPVDNVSTVYTPDRLH----EAIA 188 Query: 353 LQHGSILGFPKAKPYEGSI 371 +L P EG + Sbjct: 189 DARFVVLATPLTDETEGMV 207 >5YEQ-A nrPDB Length = 340 Score = 28.2 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 21/61 (34%), Gaps = 3/61 (4%) Query: 297 PGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIW---NPDGIDPKELEDFKL 353 +K V G+G+ G L G K E +G+ W DG P E+ Sbjct: 13 DVIKEKRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRTEEAVR 72 Query: 354 Q 354 Sbjct: 73 N 73 >4Y4M-A nrPDB Length = 290 Score = 28.2 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 20/53 (37%) Query: 281 ENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGES 333 E +A + M + V+ G G GL RYL + G K + + Sbjct: 39 ETKTTKAILKASFDMWLDIVEADVVIVGAGPSGLTCARYLAKEGFKVVVLERH 91 >1VDC-A nrPDB Length = 333 Score = 28.2 bits (61), Expect = 9.3, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 45/135 (33%), Gaps = 7/135 (5%) Query: 260 ISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRY 319 ++ G + R+S G G G ++ G P F +K V G G+ + + Sbjct: 118 LAIGAVAKRLSFVGSGEVLGGFWNRGISACAVCDGAAPIFRNKPLAVIGGGDSAMEEANF 177 Query: 320 LHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDIL 379 L ++G+K I D ++ + + + + + D+L Sbjct: 178 LTKYGSKVYI-------IHRRDAFRASKIMQQRALSNPKIDVIWNSSVVEAYGDGERDVL 230 Query: 380 IPAASEKQLTKSNAP 394 + +T + Sbjct: 231 GGLKVKNVVTGDVSD 245 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.122 0.316 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,728,146 Number of Sequences: 36641 Number of extensions: 795795 Number of successful extensions: 2885 Number of sequences better than 10.0: 132 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 62 Number of HSP's that attempted gapping in prelim test: 2534 Number of HSP's gapped (non-prelim): 190 length of query: 558 length of database: 10,336,785 effective HSP length: 102 effective length of query: 456 effective length of database: 6,599,403 effective search space: 3009327768 effective search space used: 3009327768 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.2 bits)