BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00363 (602 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2B76-A nrPDB 1253 0.0 2WDR-A nrPDB 379 e-105 5XMJ-A nrPDB 373 e-103 2H88-A nrPDB 368 e-102 4YTP-A nrPDB 366 e-101 3VR8-A nrPDB 358 4e-99 2BS2-A nrPDB 346 2e-95 1KNR-A nrPDB 246 2e-65 5KXJ-A nrPDB 241 5e-64 2E5V-A nrPDB 194 6e-50 1KSU-A nrPDB 128 7e-30 1D4E-A nrPDB 126 2e-29 1QO8-A nrPDB 126 3e-29 5ZYN-B nrPDB 84 1e-16 3GYX-A nrPDB 40 0.004 4YKF-A nrPDB 37 0.033 1FL2-A nrPDB 37 0.036 2GMH-A nrPDB 34 0.23 3OC4-A nrPDB 33 0.33 3FPZ-A nrPDB 33 0.37 1RP0-A nrPDB 32 0.77 2XSN-A nrPDB 32 0.88 5JCN-A nrPDB 31 1.2 4GCM-A nrPDB 31 1.2 2C1U-A nrPDB 31 2.0 4BPC-A nrPDB 30 2.2 5DKX-A nrPDB 30 3.0 1CHM-A nrPDB 30 3.2 5MJK-A nrPDB 30 3.6 3F8P-A nrPDB 30 4.1 1LAR-A nrPDB 29 4.9 4ZN0-A nrPDB 29 5.3 4NTC-A nrPDB 28 9.2 4J4M-A nrPDB 28 9.8 >2B76-A nrPDB Length = 602 Score = 1253 bits (3241), Expect = 0.0, Method: Compositional matrix adjust. Identities = 601/602 (99%), Positives = 602/602 (100%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH 60 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAA+GGSAAVAQDH Sbjct: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAQGGSAAVAQDH 60 Query: 61 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM 120 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM Sbjct: 61 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM 120 Query: 121 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT 180 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT Sbjct: 121 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT 180 Query: 181 LVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS 240 LVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS Sbjct: 181 LVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS 240 Query: 241 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR 300 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR Sbjct: 241 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR 300 Query: 301 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG 360 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG Sbjct: 301 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG 360 Query: 361 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGN 420 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGN Sbjct: 361 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGN 420 Query: 421 GNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL 480 GNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL Sbjct: 421 GNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL 480 Query: 481 AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGC 540 AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGC Sbjct: 481 AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGC 540 Query: 541 TERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKA 600 TERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKA Sbjct: 541 TERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKA 600 Query: 601 NG 602 NG Sbjct: 601 NG 602 >2WDR-A nrPDB Length = 588 Score = 379 bits (974), Expect = e-105, Method: Compositional matrix adjust. Identities = 239/570 (41%), Positives = 334/570 (58%), Gaps = 37/570 (6%) Query: 34 ALISKVYPMRSHTVAAEGG-SAAVAQDH-DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCP 91 AL+SKV+P RSHTV+A+GG + A+ H D++E+H +DTV G D++ +QD ++Y P Sbjct: 34 ALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGP 93 Query: 92 TEMTQLELWGCPWSRRPDGSVNVRRFGGM-------KIERTWFAADKTGFHMLHTLFQTS 144 + +LE G P+SR DG + R FGG + RT AAD+TG +LHTL+Q + Sbjct: 94 EAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQN 153 Query: 145 LQFPQIQRFDEHFVLDILVD-DGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYN 203 L+ F E + LD++ + DG V G A+ + G +V +A A V+ATGGAGR+Y+ Sbjct: 154 LK-NHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQST 212 Query: 204 TNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRY 263 TN I TGDG+GMA+ GVP++DME Q+HPTG+ G+G+L+TEGCRGEGG L+NK+G R+ Sbjct: 213 TNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERF 272 Query: 264 LQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEK 323 ++ Y P K +L RD V+++ E R+G P G L L HLG++ Sbjct: 273 MERYA---------PNAK--DLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKE 321 Query: 324 KLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIET----------DQNCETRIK 373 L RLP I EL++ + VDPVKEPIPV PT HY MGGI T ++ + + Sbjct: 322 VLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVP 381 Query: 374 GLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGV 433 GLFAVGE + V +HGANRLG NSL +LVVFGR AG E A G +A+ E+ Sbjct: 382 GLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDAS-ESDVEAS 440 Query: 434 EQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRIT 493 RL N GE+ IR + M+ ++R + M K +++L ++ER K R+ Sbjct: 441 LDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLD 500 Query: 494 DTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTL 553 DTSS FNT + +EL + + A A SA R ESRGAH R D +RDD N+L H+L Sbjct: 501 DTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFD--FPDRDDENWLCHSL 558 Query: 554 AFRDADGTTRLEYS-DVKI-TTLPPAKRVY 581 +++ TR + + K+ PP R Y Sbjct: 559 YLPESESMTRRSVNMEPKLRPAFPPKIRTY 588 >5XMJ-A nrPDB Length = 627 Score = 373 bits (957), Expect = e-103, Method: Compositional matrix adjust. Identities = 234/623 (37%), Positives = 341/623 (54%), Gaps = 50/623 (8%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGG-----SAA 55 MQ + D+ +G AG R A+ A+ A K ++S V P RSH+ AA+GG A Sbjct: 1 MQIYHTDVLCIGGALAGERVAVEASMAG--LKTIMLSLVPPRRSHSSAAQGGMQAALGNA 58 Query: 56 VAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSR--------- 106 + D DS + HF DTV G DW C+Q+V F P M ++ WG PW+R Sbjct: 59 IMGDGDSPDVHFADTVKGSDWGCDQEVARIFADTAPIVMREVAHWGVPWNRVVPGKHTYY 118 Query: 107 ---RP---------DGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFD 154 +P G ++ R FGG RT + AD TG +L+TL LQ+ + D Sbjct: 119 KGGKPFEAEEKAEKAGLIHARAFGGTAAWRTCYTADGTGRSVLNTLDTKCLQY-GVTVHD 177 Query: 155 EHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGM 214 ++ D G+ G +A + G LV A + ++ATGG GR+Y+ TN I G G Sbjct: 178 RMQAEALIHDGGNCLGCIARCLRTGELVAYLATSTLIATGGYGRIYKATTNAVICDGGGQ 237 Query: 215 GMALSHG-VPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPET 273 +AL G VP+ +ME VQ+HPTG + IL+TEGCRG+GG L++ N YR++ DY Sbjct: 238 IIALDTGLVPMGNMEAVQFHPTGTVPTDILVTEGCRGDGGTLLDVNQYRFMPDY------ 291 Query: 274 PLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFIC 333 EP +L RD VS+ RKG + +P GD ++LD+RHLGEK + +L + Sbjct: 292 ---EPDKA--QLASRDVVSRRMTEHMRKGLGVKSPYGDHLWLDIRHLGEKHITTKLREVY 346 Query: 334 ELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETR-IKGLFAVGECSSVGLHGANRL 392 ++ ++GV+P+ + IPVRPT HY+MGG+ T+++ +KGLF+ GE + +HG NRL Sbjct: 347 DICTNFLGVNPIHQLIPVRPTHHYSMGGVRTNRDGAAYGLKGLFSAGESACWDMHGFNRL 406 Query: 393 GSNSLAELVVFGRLAGEQATE--RAATAGNGNEAAIEAQAAGVEQRLKDLVN-QDGGENW 449 G NSLAE VV GR GE+ E + AT G + +A V++R+ D+V + G EN Sbjct: 407 GGNSLAETVVAGRYIGERMVEFTKGATPSFGMQYVEDAHKK-VQERITDIVTGRKGKENT 465 Query: 450 AKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIEL 509 KIRDEM M EG GI+R +QK ++KL EL +R +++ ++ N +L + + Sbjct: 466 FKIRDEMHDIMMEGVGIFRNGTDLQKAVNKLEELYDRSQKISLSSACKGMNPELSTALRI 525 Query: 510 GHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAF-RDADGTTRLEYSD 568 L +A+C A+ A+ R ESRGAH R D ER+D +L TL++ ++ LEY + Sbjct: 526 RGMLKLAQCTAYGALDRTESRGAHTRED--FPERNDKEWLNRTLSYWKEGASMPTLEYEE 583 Query: 569 VK-ITTLPPAKRVYGGEADAADK 590 +PP R YGG A++ Sbjct: 584 ASPYYEMPPGDRGYGGGVTIANE 606 >2H88-A nrPDB Length = 621 Score = 368 bits (945), Expect = e-102, Method: Compositional matrix adjust. Identities = 230/593 (38%), Positives = 330/593 (55%), Gaps = 61/593 (10%) Query: 34 ALISKVYPMRSHTVAAEGG-SAAVAQ-DHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCP 91 A ++K++P RSHTVAA+GG +AA+ + D++ +HF+DTV G DWL +QD + Y P Sbjct: 45 ACVTKLFPTRSHTVAAQGGINAALGNMEDDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAP 104 Query: 92 TEMTQLELWGCPWSRRPDGSVNVRRFGGMKIE--------RTWFAADKTGFHMLHTLFQT 143 + +LE +G P+SR +G + R FGG ++ R AD+TG +LHTL+ Sbjct: 105 AAVIELENYGMPFSRTEEGKIYQRAFGGQSLQFGKGGQAHRCCCVADRTGHSLLHTLYGR 164 Query: 144 SLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYN 203 SL++ F E+F LD+L+++G RG++A+ + +GT+ + RA V+ATGG GR Y Sbjct: 165 SLRY-DTSYFVEYFALDLLMENGECRGVIALCIEDGTIHRFRAKNTVIATGGYGRTYFSC 223 Query: 204 TNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRY 263 T+ TGDG M G+P +D+EFVQ+HPTG+ G+G L+TEGCRGEGGIL+N G R+ Sbjct: 224 TSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERF 283 Query: 264 LQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEK 323 ++ Y P+ + +L RD VS++ E R+G P D VYL L HL + Sbjct: 284 MERYA-----PVAK------DLASRDVVSRSMTIEIREGRGCG-PEKDHVYLQLHHLPPQ 331 Query: 324 KLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQ--------NCETR-IKG 374 +L RLP I E A + GVD KEPIPV PT HY MGGI T+ N E + + G Sbjct: 332 QLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDKVVPG 391 Query: 375 LFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVE 434 L+A GE +S +HGANRLG+NSL +LVVFGR A A T G AG E Sbjct: 392 LYACGEAASASVHGANRLGANSLLDLVVFGRAC---ALTIAETCKPGEPVPSIKPNAGEE 448 Query: 435 Q--RLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRI 492 L L DG ++ R M M+ ++RT ++Q+ +KL+++ ++ Sbjct: 449 SVANLDKLRFADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQIYRDLAHLKT 508 Query: 493 TDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLD--------------E 538 D V+NTDL+ T+EL + + A + A ARKESRGAH R D + Sbjct: 509 FDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKLRIDEFDYSKPLQ 568 Query: 539 GCTERD-DVNFLKHTLAFRDA-DGTTRLEYSDV--------KITTLPPAKRVY 581 G +R + ++ KHTL++ D G L+Y V +++PPA R Y Sbjct: 569 GQQKRPFEEHWRKHTLSYVDVKSGKVTLKYRPVIDRTLNEEDCSSVPPAIRSY 621 >4YTP-A nrPDB Length = 664 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 228/593 (38%), Positives = 327/593 (55%), Gaps = 61/593 (10%) Query: 34 ALISKVYPMRSHTVAAEGG-SAAVAQ-DHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCP 91 A ++K++P RSHTVAA+GG +AA+ + D++ +HF+DTV G DWL +QD + Y P Sbjct: 88 ACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAP 147 Query: 92 TEMTQLELWGCPWSRRPDGSVNVRRFGGMKIE--------RTWFAADKTGFHMLHTLFQT 143 + +LE +G P+SR DG + R FGG ++ R AD+TG +LHTL+ Sbjct: 148 ASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGR 207 Query: 144 SLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYN 203 SL++ F E+F LD+L+++G RG++A+ + +G++ +IRA V+ATGG GR Y Sbjct: 208 SLRY-DTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRARNTVVATGGYGRTYFSC 266 Query: 204 TNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRY 263 T+ TGDG M G+P +D+EFVQ+HPTG+ G+G L+TEGCRGEGGIL+N G R+ Sbjct: 267 TSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERF 326 Query: 264 LQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEK 323 ++ Y P+ + +L RD VS++ E R+G P D VYL L HL + Sbjct: 327 MERYA-----PVAK------DLASRDVVSRSMTLEIREGRGCG-PEKDHVYLQLHHLPPE 374 Query: 324 KLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETR---------IKG 374 +L RLP I E A + GVD KEPIPV PT HY MGGI T+ + + G Sbjct: 375 QLAVRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQVVPG 434 Query: 375 LFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVE 434 L+A GE + +HGANRLG+NSL +LVVFGR A A + G++ AG E Sbjct: 435 LYACGEAACASVHGANRLGANSLLDLVVFGRAC---ALSIAESCRPGDKVPSIKPNAGEE 491 Query: 435 Q--RLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRI 492 L L +G +++R M +M+ ++R ++Q+ +K+ L + ++ Sbjct: 492 SVMNLDKLRFANGTIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKILRLYGDLQHLKT 551 Query: 493 TDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLD--EGCTERD------ 544 D V+NTDL+ T+EL + + A + A ARKESRGAH R D E E D Sbjct: 552 FDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKERVDEYDYSKPIQ 611 Query: 545 -------DVNFLKHTLAFRDAD-GTTRLEYSDV--------KITTLPPAKRVY 581 ++ KHTL++ D G LEY V T+PPA R Y Sbjct: 612 GQQKKPFQEHWRKHTLSYVDVKTGKVSLEYRPVIDKTLNEADCATVPPAIRSY 664 >3VR8-A nrPDB Length = 645 Score = 358 bits (918), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 222/586 (37%), Positives = 325/586 (55%), Gaps = 56/586 (9%) Query: 32 KIALISKVYPMRSHTVAAEGGSAAV--AQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHH 89 K A+++K++P RSHT AA+GG A + + D +++HF+DT G DWL +Q+ + Y + Sbjct: 66 KTAVVTKMFPTRSHTTAAQGGINAALGSMNPDDWKWHFYDTAKGSDWLGDQNAMHYLTRN 125 Query: 90 CPTEMTQLELWGCPWSRRPDGSVNVRRFGGMK--------IERTWFAADKTGFHMLHTLF 141 +T+LE +G P+SR P+G + R FGG +RT AD+TG MLHTL+ Sbjct: 126 AVEAVTELENFGMPFSRTPEGKIYQRSFGGQSNNYGKGGVAKRTCCVADRTGHSMLHTLY 185 Query: 142 QTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYR 201 SL+ F E+F LD+L+D G G++A+ + +GT+ + R+ ++ATGG GR Y Sbjct: 186 GNSLRC-HCTFFIEYFALDLLMDKGRCVGVIALCLEDGTIHRFRSKRTIVATGGYGRAYF 244 Query: 202 YNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGY 261 T + TGDG +A G+ L D+EF+Q+HPTG+ G G L+TEG RGEGG LVN G Sbjct: 245 SCTTAHMNTGDGTALATRAGIALEDLEFIQFHPTGIYGVGCLITEGSRGEGGFLVNSEGE 304 Query: 262 RYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLG 321 R+++ Y PK K +L RD VS+A E +G + P D +YL L HL Sbjct: 305 RFMERYA---------PKAK--DLASRDVVSRAETIEIMEGRGVG-PEKDHIYLQLHHLP 352 Query: 322 EKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCET----------R 371 ++LH+RLP I E AK + GVD KEPIPV PT HY MGGI T+ + Sbjct: 353 AEQLHQRLPGISETAKIFAGVDVTKEPIPVIPTVHYNMGGIPTNYKAQVIKYTKEGGDKI 412 Query: 372 IKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAA 431 + GL+A GEC+ +HGANRLG+NSL + VVFGR E +E E Sbjct: 413 VPGLYACGECACHSVHGANRLGANSLLDAVVFGRACSINIKEELKP----DEKIPELPEG 468 Query: 432 GVEQRLKDL---VNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFK 488 E+ + +L +G A++R M M++ G++R +++ + + K+ +L + K Sbjct: 469 AGEESIANLDAVRYANGDVPTAELRLTMQKTMQKHAGVFRRGDILAEGVKKMMDLSKELK 528 Query: 489 RVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLD----------- 537 R++ TD S ++N+DL ++EL + + A +A RKESRGAH R D Sbjct: 529 RLKTTDRSLIWNSDLTESLELQNLMLNATQTIVAAENRKESRGAHARDDFPKREDEYDYS 588 Query: 538 ---EGCTERD-DVNFLKHTLAFRDA-DGTTRLEYSDVKITTLPPAK 578 EG T+R + ++ KHTL +D G L+Y V TL PA+ Sbjct: 589 KPIEGQTKRPFEKHWRKHTLTKQDPRTGHITLDYRPVIDKTLDPAE 634 >2BS2-A nrPDB Length = 660 Score = 346 bits (887), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 225/634 (35%), Positives = 327/634 (51%), Gaps = 50/634 (7%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAV---- 56 M+ D ++G G AGLRAA+A Q + + +S + RSH+ AA+GG A Sbjct: 1 MKVQYCDSLVIGGGLAGLRAAVATQQKGLSTIV--LSLIPVKRSHSAAAQGGMQASLGNS 58 Query: 57 -AQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGS---- 111 D D+ + HF DTV G DW C+Q V FV+ P + +L WG PW+R G Sbjct: 59 KMSDGDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWTRIHKGDRMAI 118 Query: 112 -----------------VNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQF-PQIQRF 153 ++ R FGG K RT + AD TG ML + L+ IQ Sbjct: 119 INAQKTTITEEDFRHGLIHSRDFGGTKKWRTCYTADATGHTMLFAVANECLKLGVSIQ-- 176 Query: 154 DEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDG 213 D + ++ DG G V +++ G ++ A ++ATGG GR+Y+ TN + G G Sbjct: 177 DRKEAIALIHQDGKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKNTTNAVVCEGTG 236 Query: 214 MGMALSHGVP-LRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPE 272 +AL G+ L +ME VQ+HPT L SGIL+TEGCRG+GGIL + +G+R++ DY Sbjct: 237 TAIALETGIAQLGNMEAVQFHPTPLFPSGILLTEGCRGDGGILRDVDGHRFMPDY----- 291 Query: 273 TPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFI 332 EP+ K EL RD VS+ RKG + +P G ++LD+ LG K + L + Sbjct: 292 ----EPEKK--ELASRDVVSRRMIEHIRKGKGVQSPYGQHLWLDISILGRKHIETNLRDV 345 Query: 333 CELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL 392 E+ + + G+DP ++ PV P HY+MGGI TD E ++KGLF+ GE + +HG NRL Sbjct: 346 QEICEYFAGIDPAEKWAPVLPMQHYSMGGIRTDYRGEAKLKGLFSAGEAACWDMHGFNRL 405 Query: 393 GSNSLAELVVFGRLAGEQATERAA-TAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAK 451 G NS++E VV G + GE E A T + +E G E +K LV G E+ K Sbjct: 406 GGNSVSEAVVAGMIVGEYFAEHCANTQVDLETKTLEKFVKGQEAYMKSLVESKGTEDVFK 465 Query: 452 IRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGH 511 I++ M M++ GI+R ++K + +L EL ++ K V I + N +L + Sbjct: 466 IKNRMKDVMDDNVGIFRDGPHLEKAVKELEELYKKSKNVGIKNKRLHANPELEEAYRVPM 525 Query: 512 GLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTT--RLEYS-- 567 L VA C+A A+ R ESRGAH R E +RDD+N+L TLA T LEY Sbjct: 526 MLKVALCVAKGALDRTESRGAHNR--EDYPKRDDINWLNRTLASWPNPEQTLPTLEYEAL 583 Query: 568 DVKITTLPPAKRVYGGEADAADKAEAANKKEKAN 601 DV + P R YG + + + + ++E+ + Sbjct: 584 DVNEMEIAPGYRGYGAKGNYIENPLSVKRQEEID 617 >1KNR-A nrPDB Length = 540 Score = 246 bits (627), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 178/551 (32%), Positives = 275/551 (49%), Gaps = 58/551 (10%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFE 64 D+ I+G+G AGL A+ A + ++ ++SK T A+GG AAV + DS + Sbjct: 8 SCDVLIIGSGAAGLSLALRLADQH---QVIVLSKGPVTEGSTFYAQGGIAAVFDETDSID 64 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSR--RPDG--SVNVRRFGGM 120 H DT+ G +C++ V++ + + + L G + +P+G S ++ R GG Sbjct: 65 SHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGH 124 Query: 121 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDG-------HVRGLVA 173 R AAD TG + TL +L P I+ + +D++V D V G Sbjct: 125 SHRRILHAADATGREVETTLVSKALNHPNIRVLERTNAVDLIVSDKIGLPGTRRVVGAWV 184 Query: 174 MNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYH 233 N + T+ A AVV+ATGGA +VY+Y TN I +GDG+ MA G + ++EF Q+H Sbjct: 185 WNRNKETVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFH 244 Query: 234 PTGL---PGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDK 290 PT L L+TE RGEG L +G R++ D+ ++ EL PRD Sbjct: 245 PTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDF------------DERGELAPRDI 292 Query: 291 VSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIP 350 V++A HE ++ D ++LD+ H + + P I E +G+D +EP+P Sbjct: 293 VARAIDHEMKRLG------ADCMFLDISHKPADFIRQHFPMIYEKLLG-LGIDLTQEPVP 345 Query: 351 VRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQ 410 + P AHYT GG+ D + T ++GL+A+GE S GLHGAN + SNSL E +V+G A E Sbjct: 346 IVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANLMASNSLLECLVYGWSAAED 405 Query: 411 ATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTP 470 T R A + + + VE + +V Q NW ++R L M + GI RT Sbjct: 406 ITRRMPYAHDISTLP-PWDESRVENPDERVVIQ---HNWHELR----LFMWDYVGIVRTT 457 Query: 471 ELMQKTIDKLAELQ----ERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMAR 526 + +++ + ++ LQ E + R+++ +EL + + VAE + AM R Sbjct: 458 KRLERALRRITMLQQEIDEYYAHFRVSNN----------LLELRNLVQVAELIVRCAMMR 507 Query: 527 KESRGAHQRLD 537 KESRG H LD Sbjct: 508 KESRGLHFTLD 518 >5KXJ-A nrPDB Length = 557 Score = 241 bits (616), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 181/557 (32%), Positives = 275/557 (49%), Gaps = 68/557 (12%) Query: 4 FQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSF 63 D+ I+G+G AGL A+ A+ + K+ ++SK T A+GG AAV + DS Sbjct: 7 LSCDVLIIGSGAAGLSLALRLAEKH---KVIVLSKGPVSEGSTFYAQGGIAAVFDETDSI 63 Query: 64 EYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSR--RPDG--SVNVRRFGG 119 H DT+ G +C++ V++ + T + L G + +P+G S ++ R GG Sbjct: 64 ASHVEDTLIAGAGICDRHAVEFVASNARTCVQWLIDQGVLFDTHVQPNGKESYHLTREGG 123 Query: 120 MKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDG-------HVRGLV 172 R AAD TG + TL + P IQ + +D+++ D V G Sbjct: 124 HSHRRILHAADATGKEVETTLVSRAQNHPNIQVLERSNAVDLIISDKMGLPGPRRVVGAW 183 Query: 173 AMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQY 232 N + + A +VV+ATGGA +VY+Y TN I +GDG+ MA G + ++EF Q+ Sbjct: 184 IWNRNKEWVETCHAKSVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQF 243 Query: 233 HPTGL---PGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRD 289 HPT L L+TE RGEG L +G R++ D ++ EL PRD Sbjct: 244 HPTALYHPQARNFLLTEALRGEGAYLKRPDGSRFMPDV------------DERGELAPRD 291 Query: 290 KVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAY-VGVDPVKEP 348 V++A HE ++ D ++LD+ H + + + P I AK +G+D KEP Sbjct: 292 IVARAIDHEMKQLG------ADCMFLDISHKPDDFVRQHFPMI--YAKLLDLGMDLTKEP 343 Query: 349 IPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAG 408 IPV P AHYT GG+ D T + GL+A+GE S GLHGANR+ SNSL E +V+G A Sbjct: 344 IPVVPAAHYTCGGVVVDDYGRTDVDGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAA 403 Query: 409 EQATERAATAGNGNEAAIEAQAAGVEQRLKD----LVNQDGGENWAKIRDEMGLAMEEGC 464 R + +++A A E R+++ +V Q NW ++R L M + Sbjct: 404 MDIDRRMPSV-----HSVDALPAWDESRVENADERVVIQ---HNWHELR----LLMWDYV 451 Query: 465 GIYRTPELMQKTIDKLAELQ----ERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMA 520 GI RT + +++ + ++ LQ E + R+++ +EL + + VAE + Sbjct: 452 GIVRTTKRLERALRRITMLQQEIDEYYANFRVSNN----------LLELRNLVQVAELIV 501 Query: 521 HSAMARKESRGAHQRLD 537 AM RKESRG H LD Sbjct: 502 RCAMMRKESRGLHFTLD 518 >2E5V-A nrPDB Length = 472 Score = 194 bits (494), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 141/401 (35%), Positives = 201/401 (50%), Gaps = 45/401 (11%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHF 67 + I+G+G AGL A +A +A K+ LISK S +A G +A+V D DS E H Sbjct: 2 IYIIGSGIAGLSAGVALRRAGK--KVTLISKRIDGGSTPIAKGGVAASVGSD-DSPELHA 58 Query: 68 HDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWF 127 DT+ GD LC+ V+Y + E WG + ++R GG R Sbjct: 59 QDTIRVGDGLCDVKTVNYVTSEAKNVIETFESWGFEFEE------DLRLEGGHTKRRVLH 112 Query: 128 AADKTGFHMLHTLFQTSLQ--FPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIR 185 D+TG + + L + + + P I E +++I V DG V G V LV+ Sbjct: 113 RTDETGREIFNFLLKLAREEGIPII----EDRLVEIRVKDGKVTGFVTEKR---GLVE-D 164 Query: 186 ANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPT--GLPGSGIL 243 + +V+ATGG +Y Y++ GDGM +A G L DMEFVQ+HPT L G L Sbjct: 165 VDKLVLATGGYSYLYEYSSTQSTNIGDGMAIAFKAGTILADMEFVQFHPTVTSLDGEVFL 224 Query: 244 MTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGN 303 +TE RGEG ++N+NG R+L +Y +K EL PRD +S+A + E KG+ Sbjct: 225 LTETLRGEGAQIINENGERFLFNY------------DKRGELAPRDILSRAIYIEMLKGH 272 Query: 304 TISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIE 363 V++DL + + + P + + + VK IP+ P AH+ GGI Sbjct: 273 K--------VFIDLSKI--EDFERKFPVVAKYLARHGHNYKVK--IPIFPAAHFVDGGIR 320 Query: 364 TDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFG 404 + E+ I L+A+GE S GLHGANRL SNSL E +VFG Sbjct: 321 VNIRGESNIVNLYAIGEVSDSGLHGANRLASNSLLEGLVFG 361 >1KSU-A nrPDB Length = 571 Score = 128 bits (322), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 124/457 (27%), Positives = 194/457 (42%), Gaps = 90/457 (19%) Query: 18 LRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH-------DSFEYHFHDT 70 AAI+A + AK+ LI K + + A GG A D DS E F DT Sbjct: 139 FSAAISATDSG--AKVILIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDT 196 Query: 71 VAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAAD 130 + GG + + +V H + + G + +V GG + R Sbjct: 197 MKGGQNINDPALVKVLSSHSKDSVDWMTAMGADLT-------DVGMMGGASVNRAHRPTG 249 Query: 131 KTGF--HMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANA 188 G H++ L+ +++ R + + + D G V+G++ M +G ++A+A Sbjct: 250 GAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKG-YYWVKADA 308 Query: 189 VVMATGGAG----RVYRYN--------TNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTG 236 V++ATGG RV + + TN GDG+ +A + G L+DM+++Q HPT Sbjct: 309 VILATGGFAKNNERVAKLDPSLKGFISTNQPGAVGDGLDVAENAGGALKDMQYIQAHPTL 368 Query: 237 LPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFW 296 G+++TE RG G ILVN+ G R++ E+ RDK S A Sbjct: 369 SVKGGVMVTEAVRGNGAILVNREGKRFVN------------------EITTRDKASAAIL 410 Query: 297 HEWRKGNTI---STPRGDVVYLD-------------LRHLGE------KKLHERLPFICE 334 + K + + R + +D L LG+ K L E + Sbjct: 411 AQTGKSAYLIFDDSVRKSLSKIDKYIGLGVAPTADSLVKLGKMEGIDGKALTETVARYNS 470 Query: 335 LAKAYVGVDPVKEPIP------------VRPTAHYTMGGIETDQNCETR------IKGLF 376 L + D + +P V P HYTMGG+ D E I GL+ Sbjct: 471 LVSSGKDTDFERPNLPRALNEGNYYAIEVTPGVHYTMGGVMIDTKAEVMNAKKQVIPGLY 530 Query: 377 AVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATE 413 GE + G+HGANRLG N++++++ FGRLAGE+A + Sbjct: 531 GAGEVTG-GVHGANRLGGNAISDIITFGRLAGEEAAK 566 >1D4E-A nrPDB Length = 572 Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 125/449 (27%), Positives = 194/449 (43%), Gaps = 93/449 (20%) Query: 31 AKIALISK-VYPMRSHTVAAEGGSAAVAQDH------DSFEYHFHDTVAGGDWLCEQDVV 83 AK+ L+ K P + +AA G +AA + D + DT+ GG + + ++V Sbjct: 150 AKVILLEKEPIPGGNTKLAAGGMNAAETKPQAKLGIEDKKQIMIDDTMKGGRNINDPELV 209 Query: 84 DYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGF--HMLHTLF 141 ++ + L G + +V R GG + R+ G H+ L+ Sbjct: 210 KVLANNSSDSIDWLTSMGADMT-------DVGRMGGASVNRSHRPTGGAGVGAHVAQVLW 262 Query: 142 QTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAG---- 197 +++ R + V + G V G++ G V I+A+AVV+A GG Sbjct: 263 DNAVKRGTDIRLNSRVVRILEDASGKVTGVLVKGEYTGYYV-IKADAVVIAAGGFAKNNE 321 Query: 198 RVYRYN--------TNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCR 249 RV +Y+ TN TGDG+ +AL G RD++++Q HPT P G+++TE R Sbjct: 322 RVSKYDPKLKGFKATNHPGATGDGLDVALQAGAATRDLQYIQAHPTYSPAGGVMITEAVR 381 Query: 250 GEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPR 309 G G I+VN+ G R++ E+ RDK S A + KG + Sbjct: 382 GNGAIVVNREGNRFMN------------------EITTRDKASAAILQQ--KGESAYLVF 421 Query: 310 GDVV---------YLDLRHLGEKKLHERLPF-----ICELAK---AYVGV---------- 342 D + Y+ L + E K E L ELAK AY G Sbjct: 422 DDSIRKSLKAIEGYVHLNIVKEGKTIEELAKQIDVPAAELAKTVTAYNGFVKSGKDAQFE 481 Query: 343 ------DPVKEP---IPVRPTAHYTMGGIETDQNCETR-------IKGLFAVGECSSVGL 386 + V P + + P H+TMGG+ D E + I GL+A GE + G+ Sbjct: 482 RPDLPRELVVAPFYALEIAPAVHHTMGGLVIDTKAEVKSEKTAKPITGLYAAGEVTG-GV 540 Query: 387 HGANRLGSNSLAELVVFGRLAGEQATERA 415 HGANRLG N+++++V +GR+AG A + A Sbjct: 541 HGANRLGGNAISDIVTYGRIAGASAAKFA 569 >1QO8-A nrPDB Length = 566 Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 131/467 (28%), Positives = 201/467 (43%), Gaps = 90/467 (19%) Query: 10 IVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH-------DS 62 +VGAG AG A++AA +A N + L+ K +++ + GG AV D Sbjct: 126 VVGAGSAGFNASLAAKKAGAN--VILVDKAPFSGGNSMISAGGMNAVGTKQQTAHGVEDK 183 Query: 63 FEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKI 122 E+ D + GG + +V + LE G +++R GG ++ Sbjct: 184 VEWFIEDAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLD-------DLKRSGGARV 236 Query: 123 ERTW--FAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT 180 +RT +G ++ TL + + + R + V ++ DD V G V G Sbjct: 237 DRTHRPHGGKSSGPEIIDTLRKAAKEQGIDTRLNSRVVKLVVNDDHSVVGAVVHGKHTGY 296 Query: 181 LVQIRANAVVMATGGAGR------VYR------YNTNGGIVTGDGMGMALSHGVPLRDME 228 + I A +VV+ATGG G YR ++N TGDG+ MA G + D++ Sbjct: 297 YM-IGAKSVVLATGGYGMNKEMIAYYRPTMKDMTSSNNITATGDGVLMAKEIGASMTDID 355 Query: 229 FVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPR 288 +VQ HPT S IL++E RG G ++VNK+G R++ EL R Sbjct: 356 WVQAHPTVGKDSRILISETVRGVGAVMVNKDGNRFIS------------------ELTTR 397 Query: 289 DKVSQAFWHE-----WRKGNTISTPRGDVV--YLDLRHLGEKKLHERLP-----FICELA 336 DK S A + W + + +V Y L L + E+L + +LA Sbjct: 398 DKASDAILKQPGQFAWIIFDNQLYKKAKMVRGYDHLEMLYKGDTVEQLAKSTGMKVADLA 457 Query: 337 KA------YVG-------------VDPVKEP---IPVRPTAHYTMGGIETDQNCETR--- 371 K YV ++ + P + V P H+TMGG+ + Sbjct: 458 KTVSDYNGYVASGKDTAFGRADMPLNMTQSPYYAVKVAPGIHHTMGGVAINTTASVLDLQ 517 Query: 372 ---IKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERA 415 I GLFA GE + G+HG NRLG N++A+ VVFGR+AG+ A + A Sbjct: 518 SKPIDGLFAAGEVTG-GVHGYNRLGGNAIADTVVFGRIAGDNAAKHA 563 >5ZYN-B nrPDB Length = 471 Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 104/358 (29%), Positives = 153/358 (42%), Gaps = 69/358 (19%) Query: 116 RFGGMKIERTWFAADKT--GFHMLHTLFQTSLQFPQIQRFDEHFV--------LDILVDD 165 + GG + RT ++ K GF ++ L S + I D + V +DI +D+ Sbjct: 115 QLGGHSVPRTHRSSGKLPPGFEIVQAL---SKKLKDISSKDSNLVQIMLNSEVVDIELDN 171 Query: 166 -GHVRGLVAMNMMEGTLVQIRANAVVMATGGAG------RVYRYN------TNGGIVTGD 212 GHV G+V M+ G ++++ VV +GG G + Y N TNG TGD Sbjct: 172 QGHVTGVVYMDE-NGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGKQTTGD 230 Query: 213 GMGMALSHGVPLRDMEFVQYHPTGLPGSG-------ILMTEGCRGEGGILVN-KNGYRYL 264 G + G L DM+ VQ HPTG L E RG GGIL++ G R+ Sbjct: 231 GQKILSKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFT 290 Query: 265 QDYG----MGPETPLGEPKNKYMEL-GPRDKVSQAFWHE---WRKGNTIS-TPRGDVV-Y 314 + + E PKN L DKV + + + + N I D++ Sbjct: 291 NELSTRDTVTMEIQSKCPKNDNRALLVMSDKVYENYTNNINFYMSKNLIKKVSINDLIRQ 350 Query: 315 LDLR--------------HLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG 360 DL+ + K +R P I + + V P H+TMG Sbjct: 351 YDLQTTASELVTELKSYSDVNTKDTFDR-PLIINAFDKDISTESTVYVGEVTPVVHFTMG 409 Query: 361 GIETDQ-------NCETRI-KGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQ 410 G++ ++ N E+ + G+FA GE S G+HGANRLG +SL E VVFG+ A + Sbjct: 410 GVKINEKSQVIKKNSESVLSNGIFAAGEVSG-GVHGANRLGGSSLLECVVFGKTAADN 466 >3GYX-A nrPDB Length = 662 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 60/236 (25%), Positives = 90/236 (38%), Gaps = 32/236 (13%) Query: 5 QADLAIVGAG----GAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVA--- 57 DL +VG G GA A A + P AKI L+ K RS VA +G SA Sbjct: 22 SVDLLMVGGGMGNCGAAFEAVRWADKYAPEAKILLVDKASLERSGAVA-QGLSAINTYLG 80 Query: 58 -QDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCP-WSRRPDG----- 110 + D + + G L +D++ H + E WG P W + G Sbjct: 81 DNNADDYVRMVRTDLMG---LVREDLIYDLGRHVDDSVHLFEEWGLPVWIKDEHGHNLDG 137 Query: 111 ----SVNVRRFGGMKIERT--WFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVD 164 + G K R+ W + + Q + + F++ +L+D Sbjct: 138 AQAKAAGKSLRNGDKPVRSGRWQIMINGESYKVIVAEAAKNALGQDRIIERIFIVKLLLD 197 Query: 165 DG---HVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMA 217 + G V N+ + +ANA+V+A GGA VYR + G+GMG A Sbjct: 198 KNTPNRIAGAVGFNLRANEVHIFKANAMVVACGGAVNVYRPRS-----VGEGMGRA 248 >4YKF-A nrPDB Length = 521 Score = 36.6 bits (83), Expect = 0.033, Method: Compositional matrix adjust. Identities = 14/26 (53%), Positives = 19/26 (73%) Query: 359 MGGIETDQNCETRIKGLFAVGECSSV 384 MG I D CET +KG+FA G+C++V Sbjct: 467 MGEIIIDAKCETNVKGVFAAGDCTTV 492 >1FL2-A nrPDB Length = 310 Score = 36.6 bits (83), Expect = 0.036, Method: Compositional matrix adjust. Identities = 14/26 (53%), Positives = 19/26 (73%) Query: 359 MGGIETDQNCETRIKGLFAVGECSSV 384 MG I D CET +KG+FA G+C++V Sbjct: 256 MGEIIIDAKCETNVKGVFAAGDCTTV 281 >2GMH-A nrPDB Length = 584 Score = 33.9 bits (76), Expect = 0.23, Method: Compositional matrix adjust. Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 12/75 (16%) Query: 1 MQTF--QADLAIVGAGGAGLRAAI----AAAQANPNAKIALISKVYPMRSHTVAAEGGSA 54 M+ F +AD+ IVGAG AGL AA AAQ + ++ L+ K + +HT+ + Sbjct: 29 MERFAEEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTL------S 82 Query: 55 AVAQDHDSFEYHFHD 69 D +FE F D Sbjct: 83 GACLDPRAFEELFPD 97 >3OC4-A nrPDB Length = 452 Score = 33.1 bits (74), Expect = 0.33, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 22/31 (70%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISK 38 + I+GA AG+ AAIA+ + P A+I+LI K Sbjct: 5 IVIIGASFAGISAAIASRKKYPQAEISLIDK 35 >3FPZ-A nrPDB Length = 326 Score = 33.1 bits (74), Expect = 0.37, Method: Compositional matrix adjust. Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 6 ADLAIVGAGGAGLRAAIAAAQANPNAKIALI-SKVYP 41 +D+ IVGAG +GL AA A+ P+ K+ +I S V P Sbjct: 66 SDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAP 102 >1RP0-A nrPDB Length = 284 Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 24/34 (70%), Gaps = 1/34 (2%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISK 38 + D+ +VGAG AGL AA ++ NPN ++A+I + Sbjct: 39 ETDVVVVGAGSAGLSAAYEISK-NPNVQVAIIEQ 71 >2XSN-A nrPDB Length = 343 Score = 32.0 bits (71), Expect = 0.88, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 315 LDLRHLG--EKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRI 372 LDL H G ++ +R I E+A Y DP+ P YT I T + T + Sbjct: 26 LDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPI-------PRVEYTAEEIATWKEVYTTL 78 Query: 373 KGLFAVGEC 381 KGL+A C Sbjct: 79 KGLYATHAC 87 >5JCN-A nrPDB Length = 451 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 4/68 (5%) Query: 360 GGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAG 419 GGI+TD ET + G++AVG+ ++ + N L E V R + EQA +A Sbjct: 294 GGIKTDAFFETSVPGVYAVGDVATFPMKMYNEL---RRVEHVDHARKSAEQAV-KAIKGK 349 Query: 420 NGNEAAIE 427 E+ +E Sbjct: 350 ESGESVVE 357 >4GCM-A nrPDB Length = 312 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYP 41 M D+AI+GAG AG+ AA+ A++A N K +I + P Sbjct: 2 MTEIDFDIAIIGAGPAGMTAAVYASRA--NLKTVMIERGIP 40 >2C1U-A nrPDB Length = 338 Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 460 MEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECM 519 ++ G + TP+ + KTI+ + E E FK + V + IE + Sbjct: 123 VQAGVEMSNTPDQVVKTINSMPEYVEAFKAAFPEEADPVTFDNFAAAIEQFEATLITPNS 182 Query: 520 AH--------SAMARKESRGAHQRLDEGCT 541 A +AM +E RG ++ GCT Sbjct: 183 AFDRFLAGDDAAMTDQEKRGLQAFMETGCT 212 >4BPC-A nrPDB Length = 582 Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 6/63 (9%) Query: 286 GPRDKVSQAFWHE-WRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDP 344 GP + ++ FW W +TI V+ LR +G +K H+ P Y VDP Sbjct: 389 GPLAETTEDFWRMLWENNSTIV-----VMLTKLREMGREKCHQYWPAERSARYQYFVVDP 443 Query: 345 VKE 347 + E Sbjct: 444 MAE 446 >5DKX-A nrPDB Length = 951 Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 255 LVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRG-DVV 313 L+N +R D PE GE + E PR+ S +W E GNT S PRG + V Sbjct: 175 LLNIEHWRPKIDPPPEPEKKEGEQQPDKKEEAPREDDS-TWWEESFGGNTDSKPRGPESV 233 Query: 314 YLDLRHLG 321 LD+ +G Sbjct: 234 GLDISFVG 241 >1CHM-A nrPDB Length = 401 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 6/71 (8%) Query: 202 YNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGY 261 Y G+ + + L G+ + ME + P GLPG+G G R ++VN+NG Sbjct: 332 YGREAGLELREDIDTVLEPGMVV-SMEPMIMLPEGLPGAG-----GYREHDILIVNENGA 385 Query: 262 RYLQDYGMGPE 272 + + GPE Sbjct: 386 ENITKFPYGPE 396 >5MJK-A nrPDB Length = 327 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 339 YVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGEC 381 YVG+DPV E + G I TD + T I G+FAVG+ Sbjct: 256 YVGLDPVAEFVSDLGITD-EAGWIITDDHMRTNIPGIFAVGDV 297 >3F8P-A nrPDB Length = 323 Score = 29.6 bits (65), Expect = 4.1, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 16/55 (29%) Query: 340 VGVDPVKEPIPVRPTAHYTMGGIETDQN--------CETRIKGLFAVGECSSVGL 386 +G DP PT GIETD N T + G+FA G+C+S L Sbjct: 247 IGFDP--------PTDFAKSNGIETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWL 293 >1LAR-A nrPDB Length = 575 Score = 29.3 bits (64), Expect = 4.9, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 6/63 (9%) Query: 286 GPRDKVSQAFWHE-WRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDP 344 GP + ++ FW W +TI V+ LR +G +K H+ P Y VDP Sbjct: 382 GPLAESTEDFWRMLWEHNSTII-----VMLTKLREMGREKCHQYWPAERSARYQYFVVDP 436 Query: 345 VKE 347 + E Sbjct: 437 MAE 439 >4ZN0-A nrPDB Length = 311 Score = 29.3 bits (64), Expect = 5.3, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 339 YVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGEC 381 YVG+ P E + V G I+TD+ ET KG++A G+C Sbjct: 242 YVGIHPNTEFVDVEKDEG---GFIKTDRWMETSEKGIYAAGDC 281 >4NTC-A nrPDB Length = 335 Score = 28.5 bits (62), Expect = 9.2, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 14/80 (17%) Query: 309 RGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKE---PIPVRPTAHYTMGG--IE 363 +GDV + HLGE + + ++ +P E P + + T GG + Sbjct: 228 KGDVAKTVIVHLGESE---------SKTEGFLVYNPQTEVNGPFAKQLALNMTEGGDILT 278 Query: 364 TDQNCETRIKGLFAVGECSS 383 T ET + G+FAVG+C++ Sbjct: 279 TPPFYETSVPGVFAVGDCAT 298 >4J4M-A nrPDB Length = 202 Score = 28.5 bits (62), Expect = 9.8, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 5/63 (7%) Query: 495 TSSVFNTDLLYTIELGHGLNVAE-----CMAHSAMARKESRGAHQRLDEGCTERDDVNFL 549 +S+VF + T ELGH L +A C S + + +L C++ D FL Sbjct: 131 SSNVFMVAVTMTHELGHNLGMAHDEAGGCACSSCIMSPAASSGPSKLFSDCSKDDYQTFL 190 Query: 550 KHT 552 +T Sbjct: 191 TNT 193 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2B76-A nrPDB 901 0.0 2BS2-A nrPDB 723 0.0 2H88-A nrPDB 716 0.0 4YTP-A nrPDB 712 0.0 5XMJ-A nrPDB 694 0.0 3VR8-A nrPDB 683 0.0 2WDR-A nrPDB 644 0.0 1KNR-A nrPDB 608 e-174 5KXJ-A nrPDB 601 e-172 2E5V-A nrPDB 426 e-119 1QO8-A nrPDB 374 e-104 1KSU-A nrPDB 366 e-101 1D4E-A nrPDB 352 2e-97 5ZYN-B nrPDB 307 1e-83 Sequences not found previously or not previously below threshold: 3GYX-A nrPDB 93 5e-19 4C3X-A nrPDB 56 7e-08 6C6P-A nrPDB 50 4e-06 3ATQ-A nrPDB 46 4e-05 2GMH-A nrPDB 42 7e-04 1ZDL-A nrPDB 41 0.001 5EZ7-A nrPDB 40 0.004 3DA1-A nrPDB 39 0.005 3OC4-A nrPDB 39 0.006 3R9U-A nrPDB 38 0.012 4GCM-A nrPDB 38 0.015 4YKF-A nrPDB 37 0.016 5JCN-A nrPDB 37 0.022 1RP0-A nrPDB 37 0.025 3FPZ-A nrPDB 37 0.027 1FL2-A nrPDB 37 0.027 5UWY-A nrPDB 35 0.096 3ISH-A nrPDB 35 0.098 1FOH-A nrPDB 35 0.10 3WDH-A nrPDB 35 0.13 1V59-A nrPDB 35 0.13 6BZ0-A nrPDB 34 0.14 5X1Y-B nrPDB 34 0.15 3CP8-A nrPDB 34 0.15 3FG2-P nrPDB 34 0.17 3IHG-A nrPDB 34 0.18 3JSK-A nrPDB 34 0.18 2ZXH-A nrPDB 34 0.19 5U63-A nrPDB 34 0.21 4AP1-A nrPDB 33 0.32 2GAG-B nrPDB 33 0.34 5MJK-A nrPDB 33 0.35 5U8W-A nrPDB 33 0.36 2Q7V-A nrPDB 33 0.38 1F8S-A nrPDB 33 0.40 5TR3-A nrPDB 33 0.41 2WOV-A nrPDB 33 0.42 5J5Z-A nrPDB 33 0.44 5USX-A nrPDB 32 0.50 1HP1-A nrPDB 32 0.53 3NIX-A nrPDB 32 0.53 2YQU-A nrPDB 32 0.54 4JNQ-A nrPDB 32 0.66 2RGJ-A nrPDB 32 0.73 2NVK-X nrPDB 32 0.83 4H7U-A nrPDB 32 0.85 3LAD-A nrPDB 32 0.89 3CP2-A nrPDB 32 0.94 3G05-A nrPDB 32 0.98 3RP7-A nrPDB 32 0.98 5W1J-A nrPDB 31 1.1 4TXK-A nrPDB 31 1.1 2BRY-A nrPDB 31 1.1 5MOG-A nrPDB 31 1.3 3IC9-A nrPDB 31 1.4 1XDI-A nrPDB 31 1.4 4NBT-A nrPDB 31 1.4 5APG-A nrPDB 31 1.4 4NEW-A nrPDB 31 1.4 2DKH-A nrPDB 31 1.5 4ZCC-A nrPDB 31 1.6 2CVJ-A nrPDB 31 1.7 2JB2-A nrPDB 31 1.7 6BWT-A nrPDB 31 1.8 4C5O-A nrPDB 31 2.2 3KKJ-A nrPDB 31 2.3 3ARQ-A nrPDB 30 2.5 1EBD-A nrPDB 30 2.8 4EMJ-A nrPDB 30 2.8 2EQ6-A nrPDB 30 3.3 1C0L-A nrPDB 30 3.3 1F6M-A nrPDB 30 3.5 5M43-A nrPDB 29 4.5 5UTH-A nrPDB 29 5.6 4Y4M-A nrPDB 29 7.4 >2B76-A nrPDB Length = 602 Score = 901 bits (2327), Expect = 0.0, Method: Composition-based stats. Identities = 601/602 (99%), Positives = 602/602 (100%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH 60 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAA+GGSAAVAQDH Sbjct: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAQGGSAAVAQDH 60 Query: 61 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM 120 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM Sbjct: 61 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM 120 Query: 121 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT 180 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT Sbjct: 121 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGT 180 Query: 181 LVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS 240 LVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS Sbjct: 181 LVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS 240 Query: 241 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR 300 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR Sbjct: 241 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR 300 Query: 301 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG 360 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG Sbjct: 301 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMG 360 Query: 361 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGN 420 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGN Sbjct: 361 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGN 420 Query: 421 GNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL 480 GNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL Sbjct: 421 GNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL 480 Query: 481 AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGC 540 AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGC Sbjct: 481 AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGC 540 Query: 541 TERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKA 600 TERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKA Sbjct: 541 TERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKA 600 Query: 601 NG 602 NG Sbjct: 601 NG 602 >2BS2-A nrPDB Length = 660 Score = 723 bits (1867), Expect = 0.0, Method: Composition-based stats. Identities = 223/633 (35%), Positives = 326/633 (51%), Gaps = 48/633 (7%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAV---- 56 M+ D ++G G AGLRAA+A Q + ++S + RSH+ AA+GG A Sbjct: 1 MKVQYCDSLVIGGGLAGLRAAVATQQKGLS--TIVLSLIPVKRSHSAAAQGGMQASLGNS 58 Query: 57 -AQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGS---- 111 D D+ + HF DTV G DW C+Q V FV+ P + +L WG PW+R G Sbjct: 59 KMSDGDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWTRIHKGDRMAI 118 Query: 112 -----------------VNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFD 154 ++ R FGG K RT + AD TG ML + L+ + D Sbjct: 119 INAQKTTITEEDFRHGLIHSRDFGGTKKWRTCYTADATGHTMLFAVANECLKLG-VSIQD 177 Query: 155 EHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGM 214 + ++ DG G V +++ G ++ A ++ATGG GR+Y+ TN + G G Sbjct: 178 RKEAIALIHQDGKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKNTTNAVVCEGTGT 237 Query: 215 GMALSHGVP-LRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPET 273 +AL G+ L +ME VQ+HPT L SGIL+TEGCRG+GGIL + +G+R++ DY Sbjct: 238 AIALETGIAQLGNMEAVQFHPTPLFPSGILLTEGCRGDGGILRDVDGHRFMPDY------ 291 Query: 274 PLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFIC 333 EP+ K EL RD VS+ RKG + +P G ++LD+ LG K + L + Sbjct: 292 ---EPEKK--ELASRDVVSRRMIEHIRKGKGVQSPYGQHLWLDISILGRKHIETNLRDVQ 346 Query: 334 ELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLG 393 E+ + + G+DP ++ PV P HY+MGGI TD E ++KGLF+ GE + +HG NRLG Sbjct: 347 EICEYFAGIDPAEKWAPVLPMQHYSMGGIRTDYRGEAKLKGLFSAGEAACWDMHGFNRLG 406 Query: 394 SNSLAELVVFGRLAGEQATERAA-TAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKI 452 NS++E VV G + GE E A T + +E G E +K LV G E+ KI Sbjct: 407 GNSVSEAVVAGMIVGEYFAEHCANTQVDLETKTLEKFVKGQEAYMKSLVESKGTEDVFKI 466 Query: 453 RDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHG 512 ++ M M++ GI+R ++K + +L EL ++ K V I + N +L + Sbjct: 467 KNRMKDVMDDNVGIFRDGPHLEKAVKELEELYKKSKNVGIKNKRLHANPELEEAYRVPMM 526 Query: 513 LNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTT--RLEYS--D 568 L VA C+A A+ R ESRGAH R D +RDD+N+L TLA T LEY D Sbjct: 527 LKVALCVAKGALDRTESRGAHNRED--YPKRDDINWLNRTLASWPNPEQTLPTLEYEALD 584 Query: 569 VKITTLPPAKRVYGGEADAADKAEAANKKEKAN 601 V + P R YG + + + + ++E+ + Sbjct: 585 VNEMEIAPGYRGYGAKGNYIENPLSVKRQEEID 617 >2H88-A nrPDB Length = 621 Score = 716 bits (1848), Expect = 0.0, Method: Composition-based stats. Identities = 227/603 (37%), Positives = 326/603 (54%), Gaps = 63/603 (10%) Query: 24 AAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQ--DHDSFEYHFHDTVAGGDWLCEQD 81 ++A N A ++K++P RSHTVAA+GG A + D++ +HF+DTV G DWL +QD Sbjct: 37 LSEAGFN--TACVTKLFPTRSHTVAAQGGINAALGNMEDDNWRWHFYDTVKGSDWLGDQD 94 Query: 82 VVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIE--------RTWFAADKTG 133 + Y P + +LE +G P+SR +G + R FGG ++ R AD+TG Sbjct: 95 AIHYMTEQAPAAVIELENYGMPFSRTEEGKIYQRAFGGQSLQFGKGGQAHRCCCVADRTG 154 Query: 134 FHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMAT 193 +LHTL+ SL++ F E+F LD+L+++G RG++A+ + +GT+ + RA V+AT Sbjct: 155 HSLLHTLYGRSLRY-DTSYFVEYFALDLLMENGECRGVIALCIEDGTIHRFRAKNTVIAT 213 Query: 194 GGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGG 253 GG GR Y T+ TGDG M G+P +D+EFVQ+HPTG+ G+G L+TEGCRGEGG Sbjct: 214 GGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGG 273 Query: 254 ILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVV 313 IL+N G R+++ Y + +L RD VS++ E R+G P D V Sbjct: 274 ILINSQGERFMERYAPVAK-----------DLASRDVVSRSMTIEIREGRGCG-PEKDHV 321 Query: 314 YLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCET--- 370 YL L HL ++L RLP I E A + GVD KEPIPV PT HY MGGI T+ + Sbjct: 322 YLQLHHLPPQQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITH 381 Query: 371 ------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEA 424 + GL+A GE +S +HGANRLG+NSL +LVVFGR E T G Sbjct: 382 VNGEDKVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALTIAE---TCKPGEPV 438 Query: 425 AIEAQAAGVEQ--RLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAE 482 AG E L L DG ++ R M M+ ++RT ++Q+ +KL++ Sbjct: 439 PSIKPNAGEESVANLDKLRFADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQ 498 Query: 483 LQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLD----- 537 + ++ D V+NTDL+ T+EL + + A + A ARKESRGAH R D Sbjct: 499 IYRDLAHLKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKLRI 558 Query: 538 ---------EGCTERD-DVNFLKHTLAFRDA-DGTTRLEYSDV--------KITTLPPAK 578 +G +R + ++ KHTL++ D G L+Y V +++PPA Sbjct: 559 DEFDYSKPLQGQQKRPFEEHWRKHTLSYVDVKSGKVTLKYRPVIDRTLNEEDCSSVPPAI 618 Query: 579 RVY 581 R Y Sbjct: 619 RSY 621 >4YTP-A nrPDB Length = 664 Score = 712 bits (1837), Expect = 0.0, Method: Composition-based stats. Identities = 225/603 (37%), Positives = 326/603 (54%), Gaps = 63/603 (10%) Query: 24 AAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQ--DHDSFEYHFHDTVAGGDWLCEQD 81 ++A N A ++K++P RSHTVAA+GG A + D++ +HF+DTV G DWL +QD Sbjct: 80 LSEAGFN--TACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQD 137 Query: 82 VVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIE--------RTWFAADKTG 133 + Y P + +LE +G P+SR DG + R FGG ++ R AD+TG Sbjct: 138 AIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTG 197 Query: 134 FHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMAT 193 +LHTL+ SL++ F E+F LD+L+++G RG++A+ + +G++ +IRA V+AT Sbjct: 198 HSLLHTLYGRSLRY-DTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRARNTVVAT 256 Query: 194 GGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGG 253 GG GR Y T+ TGDG M G+P +D+EFVQ+HPTG+ G+G L+TEGCRGEGG Sbjct: 257 GGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGG 316 Query: 254 ILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVV 313 IL+N G R+++ Y + +L RD VS++ E R+G P D V Sbjct: 317 ILINSQGERFMERYAPVAK-----------DLASRDVVSRSMTLEIREGRGCG-PEKDHV 364 Query: 314 YLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCET--- 370 YL L HL ++L RLP I E A + GVD KEPIPV PT HY MGGI T+ + Sbjct: 365 YLQLHHLPPEQLAVRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRH 424 Query: 371 ------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEA 424 + GL+A GE + +HGANRLG+NSL +LVVFGR E + G++ Sbjct: 425 VNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAE---SCRPGDKV 481 Query: 425 AIEAQAAGVEQ--RLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAE 482 AG E L L +G +++R M +M+ ++R ++Q+ +K+ Sbjct: 482 PSIKPNAGEESVMNLDKLRFANGTIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKILR 541 Query: 483 LQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLD----- 537 L + ++ D V+NTDL+ T+EL + + A + A ARKESRGAH R D Sbjct: 542 LYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKERV 601 Query: 538 ---------EGCTERD-DVNFLKHTLAFRDA-DGTTRLEYSDV--------KITTLPPAK 578 +G ++ ++ KHTL++ D G LEY V T+PPA Sbjct: 602 DEYDYSKPIQGQQKKPFQEHWRKHTLSYVDVKTGKVSLEYRPVIDKTLNEADCATVPPAI 661 Query: 579 RVY 581 R Y Sbjct: 662 RSY 664 >5XMJ-A nrPDB Length = 627 Score = 694 bits (1792), Expect = 0.0, Method: Composition-based stats. Identities = 235/640 (36%), Positives = 341/640 (53%), Gaps = 58/640 (9%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS-----AA 55 MQ + D+ +G AG R A+ A+ A K ++S V P RSH+ AA+GG A Sbjct: 1 MQIYHTDVLCIGGALAGERVAVEASMAG--LKTIMLSLVPPRRSHSSAAQGGMQAALGNA 58 Query: 56 VAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSR--------- 106 + D DS + HF DTV G DW C+Q+V F P M ++ WG PW+R Sbjct: 59 IMGDGDSPDVHFADTVKGSDWGCDQEVARIFADTAPIVMREVAHWGVPWNRVVPGKHTYY 118 Query: 107 ------------RPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFD 154 G ++ R FGG RT + AD TG +L+TL LQ+ + D Sbjct: 119 KGGKPFEAEEKAEKAGLIHARAFGGTAAWRTCYTADGTGRSVLNTLDTKCLQYG-VTVHD 177 Query: 155 EHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGM 214 ++ D G+ G +A + G LV A + ++ATGG GR+Y+ TN I G G Sbjct: 178 RMQAEALIHDGGNCLGCIARCLRTGELVAYLATSTLIATGGYGRIYKATTNAVICDGGGQ 237 Query: 215 GMALSHG-VPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPET 273 +AL G VP+ +ME VQ+HPTG + IL+TEGCRG+GG L++ N YR++ DY Sbjct: 238 IIALDTGLVPMGNMEAVQFHPTGTVPTDILVTEGCRGDGGTLLDVNQYRFMPDY------ 291 Query: 274 PLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFIC 333 + +L RD VS+ RKG + +P GD ++LD+RHLGEK + +L + Sbjct: 292 -----EPDKAQLASRDVVSRRMTEHMRKGLGVKSPYGDHLWLDIRHLGEKHITTKLREVY 346 Query: 334 ELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETR-IKGLFAVGECSSVGLHGANRL 392 ++ ++GV+P+ + IPVRPT HY+MGG+ T+++ +KGLF+ GE + +HG NRL Sbjct: 347 DICTNFLGVNPIHQLIPVRPTHHYSMGGVRTNRDGAAYGLKGLFSAGESACWDMHGFNRL 406 Query: 393 GSNSLAELVVFGRLAGEQATER--AATAGNGNEAAIEAQAAGVEQRLKDLVN-QDGGENW 449 G NSLAE VV GR GE+ E AT G + +A V++R+ D+V + G EN Sbjct: 407 GGNSLAETVVAGRYIGERMVEFTKGATPSFGMQYVEDAHKK-VQERITDIVTGRKGKENT 465 Query: 450 AKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIEL 509 KIRDEM M EG GI+R +QK ++KL EL +R +++ ++ N +L + + Sbjct: 466 FKIRDEMHDIMMEGVGIFRNGTDLQKAVNKLEELYDRSQKISLSSACKGMNPELSTALRI 525 Query: 510 GHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFR-DADGTTRLEYSD 568 L +A+C A+ A+ R ESRGAH R D ER+D +L TL++ + LEY + Sbjct: 526 RGMLKLAQCTAYGALDRTESRGAHTRED--FPERNDKEWLNRTLSYWKEGASMPTLEYEE 583 Query: 569 VK-ITTLPPAKRVYGGEADAADK--------AEAANKKEK 599 +PP R YGG A++ EAA + K Sbjct: 584 ASPYYEMPPGDRGYGGGVTIANELPPEKFVIPEAAKENLK 623 >3VR8-A nrPDB Length = 645 Score = 683 bits (1761), Expect = 0.0, Method: Composition-based stats. Identities = 233/611 (38%), Positives = 340/611 (55%), Gaps = 58/611 (9%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAV--AQDHDSFE 64 D+ I+GAGGAGLRAA+ +A K A+++K++P RSHT AA+GG A + + D ++ Sbjct: 43 DVVIIGAGGAGLRAAMGLGEAG--FKTAVVTKMFPTRSHTTAAQGGINAALGSMNPDDWK 100 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMK--- 121 +HF+DT G DWL +Q+ + Y + +T+LE +G P+SR P+G + R FGG Sbjct: 101 WHFYDTAKGSDWLGDQNAMHYLTRNAVEAVTELENFGMPFSRTPEGKIYQRSFGGQSNNY 160 Query: 122 -----IERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNM 176 +RT AD+TG MLHTL+ SL+ F E+F LD+L+D G G++A+ + Sbjct: 161 GKGGVAKRTCCVADRTGHSMLHTLYGNSLRC-HCTFFIEYFALDLLMDKGRCVGVIALCL 219 Query: 177 MEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTG 236 +GT+ + R+ ++ATGG GR Y T + TGDG +A G+ L D+EF+Q+HPTG Sbjct: 220 EDGTIHRFRSKRTIVATGGYGRAYFSCTTAHMNTGDGTALATRAGIALEDLEFIQFHPTG 279 Query: 237 LPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFW 296 + G G L+TEG RGEGG LVN G R+++ Y K +L RD VS+A Sbjct: 280 IYGVGCLITEGSRGEGGFLVNSEGERFMERYAP-----------KAKDLASRDVVSRAET 328 Query: 297 HEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAH 356 E +G + P D +YL L HL ++LH+RLP I E AK + GVD KEPIPV PT H Sbjct: 329 IEIMEGRGVG-PEKDHIYLQLHHLPAEQLHQRLPGISETAKIFAGVDVTKEPIPVIPTVH 387 Query: 357 YTMGGIETDQNCET----------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRL 406 Y MGGI T+ + + GL+A GEC+ +HGANRLG+NSL + VVFGR Sbjct: 388 YNMGGIPTNYKAQVIKYTKEGGDKIVPGLYACGECACHSVHGANRLGANSLLDAVVFGRA 447 Query: 407 AGEQATERAATAGNGNEAAIEAQAAGVEQRLKDL---VNQDGGENWAKIRDEMGLAMEEG 463 E +E E E+ + +L +G A++R M M++ Sbjct: 448 CSINIKEELKP----DEKIPELPEGAGEESIANLDAVRYANGDVPTAELRLTMQKTMQKH 503 Query: 464 CGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSA 523 G++R +++ + + K+ +L + KR++ TD S ++N+DL ++EL + + A +A Sbjct: 504 AGVFRRGDILAEGVKKMMDLSKELKRLKTTDRSLIWNSDLTESLELQNLMLNATQTIVAA 563 Query: 524 MARKESRGAHQRLD--------------EGCTERD-DVNFLKHTLAFRDA-DGTTRLEYS 567 RKESRGAH R D EG T+R + ++ KHTL +D G L+Y Sbjct: 564 ENRKESRGAHARDDFPKREDEYDYSKPIEGQTKRPFEKHWRKHTLTKQDPRTGHITLDYR 623 Query: 568 DVKITTLPPAK 578 V TL PA+ Sbjct: 624 PVIDKTLDPAE 634 >2WDR-A nrPDB Length = 588 Score = 644 bits (1662), Expect = 0.0, Method: Composition-based stats. Identities = 248/597 (41%), Positives = 343/597 (57%), Gaps = 39/597 (6%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS-AAVAQDH-DSFE 64 D ++GAGGAG+RAA+ +Q+ AL+SKV+P RSHTV+A+GG A+ H D++E Sbjct: 9 DAVVIGAGGAGMRAALQISQSGQTC--ALLSKVFPTRSHTVSAQGGITVALGNTHEDNWE 66 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIE- 123 +H +DTV G D++ +QD ++Y P + +LE G P+SR DG + R FGG Sbjct: 67 WHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNF 126 Query: 124 ------RTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDIL-VDDGHVRGLVAMNM 176 RT AAD+TG +LHTL+Q +L+ F E + LD++ DG V G A+ + Sbjct: 127 GGEQAARTAAAADRTGHALLHTLYQQNLK-NHTTIFSEWYALDLVKNQDGAVVGCTALCI 185 Query: 177 MEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTG 236 G +V +A A V+ATGGAGR+Y+ TN I TGDG+GMA+ GVP++DME Q+HPTG Sbjct: 186 ETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTG 245 Query: 237 LPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFW 296 + G+G+L+TEGCRGEGG L+NK+G R+++ Y + +L RD V+++ Sbjct: 246 IAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAK-----------DLAGRDVVARSIM 294 Query: 297 HEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAH 356 E R+G P G L L HLG++ L RLP I EL++ + VDPVKEPIPV PT H Sbjct: 295 IEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCH 354 Query: 357 YTMGGIET---------DQNCE-TRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRL 406 Y MGGI T ++ E + GLFAVGE + V +HGANRLG NSL +LVVFGR Sbjct: 355 YMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRA 414 Query: 407 AGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGI 466 AG E A G +A+ E+ RL N GE+ IR + M+ + Sbjct: 415 AGLHLQESIAEQGALRDAS-ESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSV 473 Query: 467 YRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMAR 526 +R + M K +++L ++ER K R+ DTSS FNT + +EL + + A A SA R Sbjct: 474 FREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFR 533 Query: 527 KESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY--SDVKITTLPPAKRVY 581 ESRGAH R D +RDD N+L H+L +++ TR PP R Y Sbjct: 534 TESRGAHSRFD--FPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY 588 >1KNR-A nrPDB Length = 540 Score = 608 bits (1568), Expect = e-174, Method: Composition-based stats. Identities = 179/556 (32%), Positives = 276/556 (49%), Gaps = 60/556 (10%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFE 64 D+ I+G+G AGL A+ A + ++ ++SK T A+GG AAV + DS + Sbjct: 8 SCDVLIIGSGAAGLSLALRLADQH---QVIVLSKGPVTEGSTFYAQGGIAAVFDETDSID 64 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSR--RPDG--SVNVRRFGGM 120 H DT+ G +C++ V++ + + + L G + +P+G S ++ R GG Sbjct: 65 SHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGH 124 Query: 121 KIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDG-------HVRGLVA 173 R AAD TG + TL +L P I+ + +D++V D V G Sbjct: 125 SHRRILHAADATGREVETTLVSKALNHPNIRVLERTNAVDLIVSDKIGLPGTRRVVGAWV 184 Query: 174 MNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYH 233 N + T+ A AVV+ATGGA +VY+Y TN I +GDG+ MA G + ++EF Q+H Sbjct: 185 WNRNKETVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFH 244 Query: 234 PTGLP---GSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDK 290 PT L L+TE RGEG L +G R++ D+ ++ EL PRD Sbjct: 245 PTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDF------------DERGELAPRDI 292 Query: 291 VSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIP 350 V++A HE ++ D ++LD+ H + + P I E +G+D +EP+P Sbjct: 293 VARAIDHEMKRLG------ADCMFLDISHKPADFIRQHFPMIYEKL-LGLGIDLTQEPVP 345 Query: 351 VRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQ 410 + P AHYT GG+ D + T ++GL+A+GE S GLHGAN + SNSL E +V+G A E Sbjct: 346 IVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANLMASNSLLECLVYGWSAAED 405 Query: 411 ATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTP 470 T R A + + + VE + +V Q NW ++R L M + GI RT Sbjct: 406 ITRRMPYAHDISTLP-PWDESRVENPDERVVIQ---HNWHELR----LFMWDYVGIVRTT 457 Query: 471 ELMQKTIDKLAELQ----ERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMAR 526 + +++ + ++ LQ E + R+++ +EL + + VAE + AM R Sbjct: 458 KRLERALRRITMLQQEIDEYYAHFRVSNN----------LLELRNLVQVAELIVRCAMMR 507 Query: 527 KESRGAHQRLDEGCTE 542 KESRG H LD E Sbjct: 508 KESRGLHFTLD--YPE 521 >5KXJ-A nrPDB Length = 557 Score = 601 bits (1550), Expect = e-172, Method: Composition-based stats. Identities = 177/556 (31%), Positives = 269/556 (48%), Gaps = 58/556 (10%) Query: 4 FQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSF 63 D+ I+G+G AGL A+ A+ + K+ ++SK T A+GG AAV + DS Sbjct: 7 LSCDVLIIGSGAAGLSLALRLAEKH---KVIVLSKGPVSEGSTFYAQGGIAAVFDETDSI 63 Query: 64 EYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSR--RPDG--SVNVRRFGG 119 H DT+ G +C++ V++ + T + L G + +P+G S ++ R GG Sbjct: 64 ASHVEDTLIAGAGICDRHAVEFVASNARTCVQWLIDQGVLFDTHVQPNGKESYHLTREGG 123 Query: 120 MKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDG-------HVRGLV 172 R AAD TG + TL + P IQ + +D+++ D V G Sbjct: 124 HSHRRILHAADATGKEVETTLVSRAQNHPNIQVLERSNAVDLIISDKMGLPGPRRVVGAW 183 Query: 173 AMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQY 232 N + + A +VV+ATGGA +VY+Y TN I +GDG+ MA G + ++EF Q+ Sbjct: 184 IWNRNKEWVETCHAKSVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQF 243 Query: 233 HPTGLP---GSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRD 289 HPT L L+TE RGEG L +G R++ D ++ EL PRD Sbjct: 244 HPTALYHPQARNFLLTEALRGEGAYLKRPDGSRFMPDV------------DERGELAPRD 291 Query: 290 KVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPI 349 V++A HE ++ D ++LD+ H + + + P I +G+D KEPI Sbjct: 292 IVARAIDHEMKQLG------ADCMFLDISHKPDDFVRQHFPMIYAKL-LDLGMDLTKEPI 344 Query: 350 PVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGE 409 PV P AHYT GG+ D T + GL+A+GE S GLHGANR+ SNSL E +V+G A Sbjct: 345 PVVPAAHYTCGGVVVDDYGRTDVDGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAM 404 Query: 410 QATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRT 469 R + + + + VE + +V Q NW ++R L M + GI RT Sbjct: 405 DIDRRMPSVHSVDALPA-WDESRVENADERVVIQ---HNWHELR----LLMWDYVGIVRT 456 Query: 470 PELMQKTIDKLAELQ----ERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMA 525 + +++ + ++ LQ E + R+++ +EL + + VAE + AM Sbjct: 457 TKRLERALRRITMLQQEIDEYYANFRVSNN----------LLELRNLVQVAELIVRCAMM 506 Query: 526 RKESRGAHQRLDEGCT 541 RKESRG H LD Sbjct: 507 RKESRGLHFTLDYPQQ 522 >2E5V-A nrPDB Length = 472 Score = 426 bits (1096), Expect = e-119, Method: Composition-based stats. Identities = 163/546 (29%), Positives = 240/546 (43%), Gaps = 84/546 (15%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHF 67 + I+G+G AGL A +A +A K+ LISK S +A G +A+V D DS E H Sbjct: 2 IYIIGSGIAGLSAGVALRRAGK--KVTLISKRIDGGSTPIAKGGVAASVGSD-DSPELHA 58 Query: 68 HDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWF 127 DT+ GD LC+ V+Y + E WG + ++R GG R Sbjct: 59 QDTIRVGDGLCDVKTVNYVTSEAKNVIETFESWGFEFEE------DLRLEGGHTKRRVLH 112 Query: 128 AADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRAN 187 D+TG + + L + + + D +++I V DG V G V G + + Sbjct: 113 RTDETGREIFNFLLKLAREEGIPIIEDR--LVEIRVKDGKVTGFVTEKR--GLVE--DVD 166 Query: 188 AVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPT--GLPGSGILMT 245 +V+ATGG +Y Y++ GDGM +A G L DMEFVQ+HPT L G L+T Sbjct: 167 KLVLATGGYSYLYEYSSTQSTNIGDGMAIAFKAGTILADMEFVQFHPTVTSLDGEVFLLT 226 Query: 246 EGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTI 305 E RGEG ++N+NG R+L +Y +K EL PRD +S+A + E KG+ Sbjct: 227 ETLRGEGAQIINENGERFLFNY------------DKRGELAPRDILSRAIYIEMLKGHK- 273 Query: 306 STPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETD 365 V++DL + + + P + + + VK IP+ P AH+ GGI + Sbjct: 274 -------VFIDLSKI--EDFERKFPVVAKYLARHGHNYKVK--IPIFPAAHFVDGGIRVN 322 Query: 366 QNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAA 425 E+ I L+A+GE S GLHGANRL SNSL E +VFG ++ G Sbjct: 323 IRGESNIVNLYAIGEVSDSGLHGANRLASNSLLEGLVFG----INLPRYVDSSWEG---- 374 Query: 426 IEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQE 485 + + + + G ++ E+ E GI R E + K I+ Sbjct: 375 ----ISTDDGIVHSVRIS--GNKTLSLK-EIRRINWENVGIIRNEEKLVKAIN------- 420 Query: 486 RFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDD 545 Y+ + ++ A +A RKESRG H R D D Sbjct: 421 ------------------TYSSSTQNEAIISYLTALAAEIRKESRGNHFREDYPYK---D 459 Query: 546 VNFLKH 551 N+ K Sbjct: 460 PNWEKR 465 >1QO8-A nrPDB Length = 566 Score = 374 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 131/471 (27%), Positives = 201/471 (42%), Gaps = 90/471 (19%) Query: 6 ADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH----- 60 + +VGAG AG A++AA +A N + L+ K +++ + GG AV Sbjct: 122 TQVLVVGAGSAGFNASLAAKKAGAN--VILVDKAPFSGGNSMISAGGMNAVGTKQQTAHG 179 Query: 61 --DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFG 118 D E+ D + GG + +V + LE G +++R G Sbjct: 180 VEDKVEWFIEDAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLD-------DLKRSG 232 Query: 119 GMKIERTWFAADK--TGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNM 176 G +++RT +G ++ TL + + + R + V ++ DD V G V Sbjct: 233 GARVDRTHRPHGGKSSGPEIIDTLRKAAKEQGIDTRLNSRVVKLVVNDDHSVVGAVVHGK 292 Query: 177 MEGTLVQIRANAVVMATGGAGR------VYRYN------TNGGIVTGDGMGMALSHGVPL 224 G + I A +VV+ATGG G YR +N TGDG+ MA G + Sbjct: 293 HTGYYM-IGAKSVVLATGGYGMNKEMIAYYRPTMKDMTSSNNITATGDGVLMAKEIGASM 351 Query: 225 RDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYME 284 D+++VQ HPT S IL++E RG G ++VNK+G R++ E Sbjct: 352 TDIDWVQAHPTVGKDSRILISETVRGVGAVMVNKDGNRFIS------------------E 393 Query: 285 LGPRDKVSQAFWHE-----WRKGNTISTPRGDVV--YLDLRHLGEKKLHERLP-----FI 332 L RDK S A + W + + +V Y L L + E+L + Sbjct: 394 LTTRDKASDAILKQPGQFAWIIFDNQLYKKAKMVRGYDHLEMLYKGDTVEQLAKSTGMKV 453 Query: 333 CELAKA---YVG----------------VDPVKEP---IPVRPTAHYTMGGIETDQNCET 370 +LAK Y G ++ + P + V P H+TMGG+ + Sbjct: 454 ADLAKTVSDYNGYVASGKDTAFGRADMPLNMTQSPYYAVKVAPGIHHTMGGVAINTTASV 513 Query: 371 R------IKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERA 415 I GLFA GE + G+HG NRLG N++A+ VVFGR+AG+ A + A Sbjct: 514 LDLQSKPIDGLFAAGEVTG-GVHGYNRLGGNAIADTVVFGRIAGDNAAKHA 563 >1KSU-A nrPDB Length = 571 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 124/460 (26%), Positives = 195/460 (42%), Gaps = 90/460 (19%) Query: 18 LRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH-------DSFEYHFHDT 70 AAI+A + AK+ LI K + + A GG A D DS E F DT Sbjct: 139 FSAAISATDSG--AKVILIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDT 196 Query: 71 VAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAAD 130 + GG + + +V H + + G + +V GG + R Sbjct: 197 MKGGQNINDPALVKVLSSHSKDSVDWMTAMGADLT-------DVGMMGGASVNRAHRPTG 249 Query: 131 KTGF--HMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANA 188 G H++ L+ +++ R + + + D G V+G++ M +G ++A+A Sbjct: 250 GAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGYY-WVKADA 308 Query: 189 VVMATGGAG----RVYRYN--------TNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTG 236 V++ATGG RV + + TN GDG+ +A + G L+DM+++Q HPT Sbjct: 309 VILATGGFAKNNERVAKLDPSLKGFISTNQPGAVGDGLDVAENAGGALKDMQYIQAHPTL 368 Query: 237 LPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFW 296 G+++TE RG G ILVN+ G R++ E+ RDK S A Sbjct: 369 SVKGGVMVTEAVRGNGAILVNREGKRFVN------------------EITTRDKASAAIL 410 Query: 297 HEWRKGNTI---STPRGDVVYLD-------------LRHLGE------KKLHERLPFICE 334 + K + + R + +D L LG+ K L E + Sbjct: 411 AQTGKSAYLIFDDSVRKSLSKIDKYIGLGVAPTADSLVKLGKMEGIDGKALTETVARYNS 470 Query: 335 LAKAYVGVDPVKEPIP------------VRPTAHYTMGGIETDQNCETR------IKGLF 376 L + D + +P V P HYTMGG+ D E I GL+ Sbjct: 471 LVSSGKDTDFERPNLPRALNEGNYYAIEVTPGVHYTMGGVMIDTKAEVMNAKKQVIPGLY 530 Query: 377 AVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA 416 GE + G+HGANRLG N++++++ FGRLAGE+A + + Sbjct: 531 GAGEVTG-GVHGANRLGGNAISDIITFGRLAGEEAAKYSK 569 >1D4E-A nrPDB Length = 572 Score = 352 bits (904), Expect = 2e-97, Method: Composition-based stats. Identities = 132/475 (27%), Positives = 205/475 (43%), Gaps = 95/475 (20%) Query: 6 ADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH----- 60 D+ I+G+GGAGL AA++A A AK+ L+ K +T A GG A Sbjct: 127 TDVVIIGSGGAGLAAAVSARDAG--AKVILLEKEPIPGGNTKLAAGGMNAAETKPQAKLG 184 Query: 61 --DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFG 118 D + DT+ GG + + ++V ++ + L G + +V R G Sbjct: 185 IEDKKQIMIDDTMKGGRNINDPELVKVLANNSSDSIDWLTSMGADMT-------DVGRMG 237 Query: 119 GMKIERTWFAADKTGF--HMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNM 176 G + R+ G H+ L+ +++ R + V + G V G++ Sbjct: 238 GASVNRSHRPTGGAGVGAHVAQVLWDNAVKRGTDIRLNSRVVRILEDASGKVTGVLVKGE 297 Query: 177 MEGTLVQIRANAVVMATGGAG----RVYRYN--------TNGGIVTGDGMGMALSHGVPL 224 G V I+A+AVV+A GG RV +Y+ TN TGDG+ +AL G Sbjct: 298 YTGYYV-IKADAVVIAAGGFAKNNERVSKYDPKLKGFKATNHPGATGDGLDVALQAGAAT 356 Query: 225 RDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYME 284 RD++++Q HPT P G+++TE RG G I+VN+ G R++ E Sbjct: 357 RDLQYIQAHPTYSPAGGVMITEAVRGNGAIVVNREGNRFMN------------------E 398 Query: 285 LGPRDKVSQAFWHEWRKGNTISTPRGDVV---------YLDLRHLGEKKLHERLPF---- 331 + RDK S A + KG + D + Y+ L + E K E L Sbjct: 399 ITTRDKASAAILQQ--KGESAYLVFDDSIRKSLKAIEGYVHLNIVKEGKTIEELAKQIDV 456 Query: 332 ----ICELAKAYVGV----------------DPVKEP---IPVRPTAHYTMGGIETDQNC 368 + + AY G + V P + + P H+TMGG+ D Sbjct: 457 PAAELAKTVTAYNGFVKSGKDAQFERPDLPRELVVAPFYALEIAPAVHHTMGGLVIDTKA 516 Query: 369 ETR-------IKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA 416 E + I GL+A GE + G+HGANRLG N+++++V +GR+AG A + A Sbjct: 517 EVKSEKTAKPITGLYAAGEVTG-GVHGANRLGGNAISDIVTYGRIAGASAAKFAK 570 >5ZYN-B nrPDB Length = 471 Score = 307 bits (786), Expect = 1e-83, Method: Composition-based stats. Identities = 117/476 (24%), Positives = 186/476 (39%), Gaps = 83/476 (17%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH------- 60 + ++G+G AGL + + L+ K + +++ A G D Sbjct: 7 VVVIGSGLAGLTTSNRLISK-YRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVM 65 Query: 61 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM 120 D+ E DT+ ++D + + L+ + + D + + GG Sbjct: 66 DTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIRWLQT---EFDLKLDL---LAQLGGH 119 Query: 121 KIERTWFAADKT--GFHMLHTLFQTSLQFPQIQRFDEHFV--------LDILVDD-GHVR 169 + RT ++ K GF ++ L S + I D + V +DI +D+ GHV Sbjct: 120 SVPRTHRSSGKLPPGFEIVQAL---SKKLKDISSKDSNLVQIMLNSEVVDIELDNQGHVT 176 Query: 170 GLVAMNMMEGTLVQIRANAVVMATGGAGR------------VYRYNTNGGIVTGDGMGMA 217 G+V M+ G ++++ VV +GG G ++ TNG TGDG + Sbjct: 177 GVVYMD-ENGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGKQTTGDGQKIL 235 Query: 218 LSHGVPLRDMEFVQYHPTGLPGSG-------ILMTEGCRGEGGILVNK-NGYRYLQDYG- 268 G L DM+ VQ HPTG L E RG GGIL++ G R+ + Sbjct: 236 SKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFTNELST 295 Query: 269 ---MGPETPLGEPKNKYME-LGPRDKVSQAFWHE----WRKGNTISTPRGDVV-YLDL-- 317 + E PKN L DKV + + + K D++ DL Sbjct: 296 RDTVTMEIQSKCPKNDNRALLVMSDKVYENYTNNINFYMSKNLIKKVSINDLIRQYDLQT 355 Query: 318 ------------RHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETD 365 + K +R P I + + V P H+TMGG++ + Sbjct: 356 TASELVTELKSYSDVNTKDTFDR-PLIINAFDKDISTESTVYVGEVTPVVHFTMGGVKIN 414 Query: 366 QNCETRIK--------GLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATE 413 + + K G+FA GE S G+HGANRLG +SL E VVFG+ A + + Sbjct: 415 EKSQVIKKNSESVLSNGIFAAGEVSG-GVHGANRLGGSSLLECVVFGKTAADNIAK 469 >3GYX-A nrPDB Length = 662 Score = 92.5 bits (228), Expect = 5e-19, Method: Composition-based stats. Identities = 126/676 (18%), Positives = 206/676 (30%), Gaps = 141/676 (20%) Query: 5 QADLAIVGAG----GAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH 60 DL +VG G GA A A + P AKI L+ K RS V A+G SA Sbjct: 22 SVDLLMVGGGMGNCGAAFEAVRWADKYAPEAKILLVDKASLERSGAV-AQGLSAINTYLG 80 Query: 61 DSFEYHFHDTVAGGD----WLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRR 116 D+ + D V L +D++ H + E WG P + + N+ Sbjct: 81 DN---NADDYVRMVRTDLMGLVREDLIYDLGRHVDDSVHLFEEWGLPVWIKDEHGHNLDG 137 Query: 117 FGGMKIERTWFAAD---KTGF-------HMLHTLFQTSLQ--FPQIQRFDEHFVLDILVD 164 ++ D ++G + + + Q + + F++ +L+D Sbjct: 138 AQAKAAGKSLRNGDKPVRSGRWQIMINGESYKVIVAEAAKNALGQDRIIERIFIVKLLLD 197 Query: 165 DG---HVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL--- 218 + G V N+ + +ANA+V+A GGA VYR G+GMG A Sbjct: 198 KNTPNRIAGAVGFNLRANEVHIFKANAMVVACGGAVNVYR-----PRSVGEGMGRAWYPV 252 Query: 219 -----------SHGVPLRDMEFVQYHPT------GLPGSGILMTEG----CRGEGGILVN 257 G + ME ++ P G G+ L+ + C+GE N Sbjct: 253 WNAGSTYTMCAQVGAEMTMME-NRFVPARFKDGYGPVGAWFLLFKAKATNCKGEDYCATN 311 Query: 258 KNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNT---------ISTP 308 + P E + P + E R+G + T Sbjct: 312 R-----------AMLKPYEERGYAKGHVIPTCLRNHMMLREMREGRGPIYMDTKTALQTS 360 Query: 309 RGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVD--PVKEPIPVRPTAHYTMGG----- 361 + +HL + + L A + + P + + PT Y +G Sbjct: 361 FATMSPAQQKHLEAEAWEDFLDMCVGQANLWAATNCAPEERGSEIMPTEPYLLGSHSGCC 420 Query: 362 -----------IETDQNCE----------TRIKGLFAVGECSSVGLHGANRLGSNSLAEL 400 + D T ++GL+ + H + S S AE Sbjct: 421 GIWASGPDEAWVPEDYKVRAANGKVYNRMTTVEGLWTCADGVGASGH---KFSSGSHAE- 476 Query: 401 VVFGRLAGEQAT-----------ERAATAGNGNEA---AIEAQAAGVEQRLKDLVNQDGG 446 GR+ G+Q E TA G +VN + Sbjct: 477 ---GRIVGKQMVRWYLDHKDFKPEFVETAEELKTLIYRPYYNYEKGKGASTCPVVNPE-Y 532 Query: 447 ENWAKIRDEMGLAMEEG---CGIYRTPE--LMQKTIDKLAELQERFKRVRITDTSSVFNT 501 + + +E G Y L+ + L+E +++ Sbjct: 533 ISPKNFMMRLIKCTDEYGGGVGTYYNTSKALLDTGFWLMEMLEEDS--LKLAARDLH--- 587 Query: 502 DLLYTIELGHGLNVAECMAHSAMARKESR--GAHQRLDEGCTERDDVNFLKHTLAFRDAD 559 +LL E H L R+ESR G + R D DD + + D Sbjct: 588 ELLRCWENYHRLWTVRLHMQHIAFREESRYPGFYYRAD--FLGLDDSKWKCFVNSKYDPA 645 Query: 560 GTTRLEYSDVKITTLP 575 + +P Sbjct: 646 KKETKIFKKPYYQIIP 661 >4C3X-A nrPDB Length = 530 Score = 55.6 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 60/319 (18%), Positives = 99/319 (31%), Gaps = 64/319 (20%) Query: 3 TFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQD--- 59 T + D+ +VG+GG L A AA ++ K + + Sbjct: 25 TSECDVLVVGSGGGALTGAYTAAAQGLT--TIVLEKTDRFGGTSAYSGASIWLPGTQVQE 82 Query: 60 ----HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLE-LWGCPWSRRPDGSVNV 114 DS E + + E + D +V P + LE + R Sbjct: 83 RAGLPDSTE-NARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYK 141 Query: 115 ---RRFGGMKIE----------------RTWFAADKTG-----------FHMLHTLFQTS 144 R G I R D+TG ++ L Sbjct: 142 AEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAV 201 Query: 145 LQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRA-NAVVMATGGA------- 196 + + E + ++V+DG V G G +I+A V+MA GG Sbjct: 202 QSTGKAELRTESVLTSLIVEDGRVVGAEV--ESGGETQRIKANRGVLMAAGGIEGNAEMR 259 Query: 197 ------GRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSG---ILMTEG 247 G+ G TGD + ++ G ++ + P G ++ G Sbjct: 260 EQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMV--G 317 Query: 248 CRGEGGILVNKNGYRYLQD 266 R GG++V+ G RYL + Sbjct: 318 VR--GGLVVDSAGERYLNE 334 >6C6P-A nrPDB Length = 458 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 53/288 (18%), Positives = 101/288 (35%), Gaps = 36/288 (12%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 ++ IVGAG G A ++ + P R + G V +D Sbjct: 9 EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKD-----LG 63 Query: 67 FHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTW 126 DTV G + VV+ ++ H ++++ P+ + V Sbjct: 64 LGDTVEG----LDAQVVNGYMIHDQESKSEVQ---IPYPLSENNQV-------QSGRAFH 109 Query: 127 FAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRA 186 G ++ +L + ++ P +F E VL +L +D V G+ + G + ++ A Sbjct: 110 H-----GRFIM-SLRKAAMAEPN-AKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHA 162 Query: 187 NAVVMATGGAGRVYRYNTNGGIVTGD---GMGMALSHGVPLRDMEFVQYHPTGLPGSGIL 243 V+A G + + + + G M + E + +P+ +L Sbjct: 163 PLTVVADGLFSKFRKSLVSNKVSVSSHFVGFLMKNAPQFKANHAELILANPSP-----VL 217 Query: 244 MTEGCRGEGGILVNKNGY--RYLQDYGMGPETPLGEPKNKYMELGPRD 289 + + E +LV+ G R L++Y + P K L D Sbjct: 218 IYQISSSETRVLVDIRGEMPRNLREYMVEKIYPQIPDHLKEPFLEATD 265 >3ATQ-A nrPDB Length = 453 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 43/210 (20%), Positives = 75/210 (35%), Gaps = 53/210 (25%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH 60 M+ + D+ I+G G AG AA ++ KI L+ Sbjct: 2 MKELKYDVLIIGGGFAGSSAAYQLSRRG--LKILLV------------------------ 35 Query: 61 DSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGM 120 DS ++ GD C V + G P+ P G + G+ Sbjct: 36 DSKPWN-----RIGDKPCGDAVSK----------AHFDKLGMPY---PKGEELENKINGI 77 Query: 121 KIE----RTWFAADKTGFHMLHTLFQTSL----QFPQIQRFDEHFVLDILVDDGHVRGLV 172 K+ +T + + GF + L+ + Q ++ +D + + +DG+V+G V Sbjct: 78 KLYSPDMQTVWTVNGEGFELNAPLYNQRVLKEAQDRGVEIWDLTTAMKPIFEDGYVKGAV 137 Query: 173 AMNMMEGTLVQIRANAVVMATGGAGRVYRY 202 N + + + VV AT G R +R Sbjct: 138 LFNRRTNEELTVYSKVVVEAT-GYSRSFRS 166 >2GMH-A nrPDB Length = 584 Score = 42.1 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 46/214 (21%), Positives = 74/214 (34%), Gaps = 44/214 (20%) Query: 5 QADLAIVGAGGAGLRAAIA----AAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH 60 +AD+ IVGAG AGL AA AAQ + ++ L+ K + +HT++ D Sbjct: 35 EADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGA------CLDP 88 Query: 61 DSFEYHFHDTVAGGDWLCEQ---DVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRF 117 +FE F D G L D + L G P + G+ VR Sbjct: 89 RAFEELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILP--GLPMNN--HGNYVVRL- 143 Query: 118 GGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMN-- 175 G + A+ G + +P + +DG V+G+ + Sbjct: 144 -GHLVSWMGEQAEALGVEV----------YPGYAA-----AEILFHEDGSVKGIATNDVG 187 Query: 176 -MMEGTLVQ-------IRANAVVMATGGAGRVYR 201 +G + A + A G G + + Sbjct: 188 IQKDGAPKTTFERGLELHAKVTIFAEGCHGHLAK 221 >1ZDL-A nrPDB Length = 517 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 70/394 (17%), Positives = 119/394 (30%), Gaps = 85/394 (21%) Query: 4 FQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPM-RSHTVAAEGGSAAVAQDHDS 62 DL ++G G GL A AAQ K+A+ V P R G V Sbjct: 31 QSFDLLVIGGGSGGLACAKEAAQLGK--KVAVADYVEPSPRGTKWGLGGTCVNVGCIP-- 86 Query: 63 FEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKI 122 + + GG + +G W N + + Sbjct: 87 KKLMHQAALLGG------------------MIRDAHHYG--WEVAQPVQHNWKTM--AEA 124 Query: 123 ERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLV 182 + + G + L +++ I VD+ VRG+ G Sbjct: 125 VQNHVKSLNWGHRV--QLQDRKVKYFNI--------KASFVDEHTVRGV----DKGGKAT 170 Query: 183 QIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHP--TGLPGS 240 + A +V+ATGG R V G AL +G+ D+ +++ P T + G+ Sbjct: 171 LLSAEHIVIATGGRPRY------PTQVKG-----ALEYGITSDDIFWLKESPGKTLVVGA 219 Query: 241 GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWR 300 + E GI ++ M PL + L E Sbjct: 220 SYVALECAGFLTGIGLDTT--------VMMRSIPLRGFDQQMSSLVT----------EHM 261 Query: 301 KGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRP---TAHY 357 + + +G V ++ L +L + D V I P T + Sbjct: 262 ESHGTQFLKG-CVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNL 320 Query: 358 TMGGIETDQNCE---------TRIKGLFAVGECS 382 GI T+ + T + ++A+G+ + Sbjct: 321 EKAGISTNPKNQKIIVDAQEATSVPHIYAIGDVA 354 >5EZ7-A nrPDB Length = 392 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 19/50 (38%), Gaps = 2/50 (4%) Query: 2 QTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEG 51 Q D+ IVG G AGL +A L+ +V ++G Sbjct: 4 QALSTDILIVGGGIAGLWLNARLRRAGYA--TVLVESASLGGGQSVKSQG 51 >3DA1-A nrPDB Length = 561 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 40/114 (35%), Gaps = 6/114 (5%) Query: 81 DVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTL 140 V DY E + + P + GG+ +E + D + + Sbjct: 122 KVYDYLADVRKDERRYMLNEKQTLEKEPLLRKENLKGGGIYVE---YRTDDARLTLE--I 176 Query: 141 FQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATG 194 + ++ + + V + D G V G+VA + + T I A VV A G Sbjct: 177 MKEAVARGAVA-LNYMKVESFIYDQGKVVGVVAKDRLTDTTHTIYAKKVVNAAG 229 >3OC4-A nrPDB Length = 452 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 47/110 (42%), Gaps = 16/110 (14%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHF 67 + I+GA AG+ AAIA+ + P A+I+LI K + GG +A H Sbjct: 5 IVIIGASFAGISAAIASRKKYPQAEISLIDKQATVG----YLSGGLSAYFN-------HT 53 Query: 68 HDTVAGGDWLCEQDV----VDYFVHHCPTEMTQLELWGCPWSRRPDGSVN 113 + + ++ E+++ + ++ M +E W+R+ + Sbjct: 54 INELHEARYITEEELRRQKIQLLLNREVVAMD-VENQLIAWTRKEEQQWY 102 >3R9U-A nrPDB Length = 315 Score = 37.8 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAE 50 D+AI+G G AGL A + A + + + K P T ++E Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLK-NVVMFEKGMPGGQITSSSE 48 >4GCM-A nrPDB Length = 312 Score = 37.8 bits (86), Expect = 0.015, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMR 43 D+AI+GAG AG+ AA+ A++A N K +I + P Sbjct: 8 DIAIIGAGPAGMTAAVYASRA--NLKTVMIERGIPGG 42 Score = 34.8 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 46/255 (18%), Positives = 87/255 (34%), Gaps = 30/255 (11%) Query: 132 TGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVM 191 TG + +F+ + +F + ++ + ++ D G + G ++ A AV++ Sbjct: 60 TGPDLSTKMFEHAKKFGAVYQYGDIKSVE---DKGE-----YKVINFGN-KELTAKAVII 110 Query: 192 ATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGE 251 ATG Y+ G G G++ + D F + + G G E E Sbjct: 111 ATGA---EYKKIGVPGEQELGGRGVSY---CAVCDGAFFKNKRLFVIGGGDSAVE----E 160 Query: 252 GGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGD 311 G L ++ + + + ++ W K + Sbjct: 161 GTFL-----TKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVG 215 Query: 312 VVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETR 371 V L G ++ HE + Y+G+ P+ P +G I T + T Sbjct: 216 SVTLTSTKDGSEETHE-----ADGVFIYIGMKPLTAPFKDL-GITNDVGYIVTKDDMTTS 269 Query: 372 IKGLFAVGECSSVGL 386 + G+FA G+ GL Sbjct: 270 VPGIFAAGDVRDKGL 284 >4YKF-A nrPDB Length = 521 Score = 37.4 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 39/218 (17%), Positives = 71/218 (32%), Gaps = 39/218 (17%) Query: 174 MNMMEGTLVQIRANAVVMATGGAGR------VYRYNTNGGIVTGDGMGMALSHGVPLRDM 227 + + ++A ++++ATG R +Y T G P D Sbjct: 303 HQIETASGAVLKARSIIVATGAKWRNMNVPGEDQYRTKGVTY------------CPHCDG 350 Query: 228 EFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGP 287 + + G G E GI+ + + + +K L Sbjct: 351 PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKADQVLQ-----DKLRSLKN 405 Query: 288 RDKVSQAFWHEWRKGNT---ISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDP 344 D + A E KG+ + D V D+ ++ + ++ + V+ Sbjct: 406 VDIILNAQTTEV-KGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVER 464 Query: 345 VKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECS 382 + MG I D CET +KG+FA G+C+ Sbjct: 465 NR------------MGEIIIDAKCETNVKGVFAAGDCT 490 >5JCN-A nrPDB Length = 451 Score = 37.1 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 3/67 (4%) Query: 360 GGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAG 419 GGI+TD ET + G++AVG+ ++ + N L E V R + EQA + Sbjct: 294 GGIKTDAFFETSVPGVYAVGDVATFPMKMYNEL---RRVEHVDHARKSAEQAVKAIKGKE 350 Query: 420 NGNEAAI 426 +G Sbjct: 351 SGESVVE 357 >1RP0-A nrPDB Length = 284 Score = 37.1 bits (84), Expect = 0.025, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 54/169 (31%), Gaps = 49/169 (28%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFE 64 + D+ +VGAG AGL AA + NPN ++A+I + Sbjct: 39 ETDVVVVGAGSAGLSAAYEIS-KNPNVQVAIIEQSVSPG--------------------- 76 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIER 124 GG WL Q V L+ G + + V Sbjct: 77 --------GGAWLGGQLFSAMIVR--KPAHLFLDEIGVAYDEQDTYVV------------ 114 Query: 125 TWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVA 173 AA T T+ L P ++ F+ D++V V G+V Sbjct: 115 VKHAALFT-----STIMSKLLARPNVKLFNAVAAEDLIVKGNRVGGVVT 158 >3FPZ-A nrPDB Length = 326 Score = 36.7 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 6 ADLAIVGAGGAGLRAAIAAAQANPNAKIALI-SKVYPMRSHTVAAEGGSAAVAQDH 60 +D+ IVGAG +GL AA A+ P+ K+ +I S V P + + SA V + Sbjct: 66 SDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRKP 121 >1FL2-A nrPDB Length = 310 Score = 36.7 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 38/212 (17%), Positives = 70/212 (33%), Gaps = 27/212 (12%) Query: 174 MNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYH 233 + + ++A ++++ATG R N + D P D + Sbjct: 92 HQIETASGAVLKARSIIVATGAKWR------NMNVPGEDQYRTKGVTYCPHCDGPLFKGK 145 Query: 234 PTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQ 293 + G G E GI+ + + + +K L D + Sbjct: 146 RVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKADQVLQ-----DKLRSLKNVDIILN 200 Query: 294 AFWHEWRKGNT---ISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIP 350 A E KG+ + D V D+ ++ + ++ + V+ + Sbjct: 201 AQTTEV-KGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVERNR---- 255 Query: 351 VRPTAHYTMGGIETDQNCETRIKGLFAVGECS 382 MG I D CET +KG+FA G+C+ Sbjct: 256 --------MGEIIIDAKCETNVKGVFAAGDCT 279 >5UWY-A nrPDB Length = 308 Score = 35.1 bits (79), Expect = 0.096, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 2/37 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMR 43 D I+G+G AG+ AA+ AA++N + +A+I + P Sbjct: 6 DTLIIGSGPAGMTAALYAARSNLS--VAIIEQGAPGG 40 Score = 29.4 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 38/98 (38%), Gaps = 8/98 (8%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 DL +VG G + + AI Q K+ ++ + +R+ + + A A D F + Sbjct: 145 DLLVVGGGDSAVEEAIYLTQ--FAKKVTVVHRRDQLRAQKILQD---RAFANDKVDFIW- 198 Query: 67 FHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPW 104 D+V + V + + + T +G + Sbjct: 199 --DSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVF 234 >3ISH-A nrPDB Length = 311 Score = 35.1 bits (79), Expect = 0.098, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAE 50 D AI+G G AGL A + A + + L K P T ++E Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAV-LFEKGMPGGQITGSSE 45 >1FOH-A nrPDB Length = 664 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 7/49 (14%) Query: 5 QADLAIVGAGGAGLRAAIAAA---QANPNAKIALISKVYPMRSHTVAAE 50 D+ IVGAG AGL AA + + P+ K+ +I K RS V Sbjct: 7 YCDVLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDK----RSTKVYNG 51 >3WDH-A nrPDB Length = 710 Score = 34.8 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 37/107 (34%), Gaps = 2/107 (1%) Query: 177 MEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLR-DMEFVQYHPT 235 EG V ++ A VM T +Y Y+ N T D P D+ HPT Sbjct: 82 EEGWQVPLQVGA-VMRTKAFDDLYAYDGNDLGATYDPEKTTFKVWAPTATDVLLKLIHPT 140 Query: 236 GLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKY 282 + +MT +G V + R+L Y E + Y Sbjct: 141 TKEETTYVMTREKKGLWTYTVYDDVERFLYTYMTYVNFIWREAVDPY 187 >1V59-A nrPDB Length = 478 Score = 34.8 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 34/95 (35%), Gaps = 5/95 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAE--GGSAAVAQDHDSFE 64 D+ I+G G AG AAI AAQ N A + K + + A + H + Sbjct: 7 DVVIIGGGPAGYVAAIKAAQLGFN--TACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQ 64 Query: 65 YHFHDTVAGGDWLCEQDV-VDYFVHHCPTEMTQLE 98 H G D + + V F + QL Sbjct: 65 MHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLT 99 >6BZ0-A nrPDB Length = 480 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 4 FQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTV 47 Q DL ++G G G AAI AAQ K+A I K ++ Sbjct: 6 QQFDLVVIGGGPGGYEAAIRAAQLG--FKVACIEKRIHNGKPSL 47 >5X1Y-B nrPDB Length = 554 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS 44 DL I+G+G A +AI A + AK+ +I + + Sbjct: 86 DLLIIGSGAAAFSSAIKAIEYG--AKVGMIERGTVGGT 121 >3CP8-A nrPDB Length = 641 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 22/48 (45%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSA 54 D+ +VGAG AG AA+A A+ + + R A GG A Sbjct: 23 DVIVVGAGHAGCEAALAVARGGLHCLLITSDLSAVARMSCNPAIGGVA 70 >3FG2-P nrPDB Length = 404 Score = 34.0 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 10/69 (14%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALIS-------KVYPMRSHTVAAEGGSAAVAQDH 60 + I GAG AG + A++ QA +IALI+ + P+ + + G ++ Sbjct: 4 VLIAGAGHAGFQVAVSLRQAKYPGRIALINDEKHLPYQRPPLSKAYLKSGGDPNSLMF-- 61 Query: 61 DSFEYHFHD 69 E F D Sbjct: 62 -RPEKFFQD 69 >3IHG-A nrPDB Length = 535 Score = 34.0 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAE 50 M + D+ +VGAG GL A+ A+ ++ ++ + + + AA Sbjct: 1 MNDHEVDVLVVGAGLGGLSTAMFLARQG--VRVLVVERRPGLSPYPRAAG 48 >3JSK-A nrPDB Length = 344 Score = 34.0 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 49/163 (30%), Gaps = 48/163 (29%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFE 64 + D+ IVGAG GL AA + P+ +I ++ Sbjct: 79 ETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPG--------------------- 117 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIER 124 GG WL Q + L+ G P+ D V Sbjct: 118 --------GGAWLGGQLFSAMVMRKPADVF--LDEVGVPYEDEGDYVV------------ 155 Query: 125 TWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGH 167 AA T T+ LQ P ++ F+ V D++ H Sbjct: 156 VKHAALFT-----STVLSKVLQRPNVKLFNATTVEDLITRKHH 193 >2ZXH-A nrPDB Length = 637 Score = 34.0 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 38/218 (17%), Positives = 70/218 (32%), Gaps = 48/218 (22%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 D+ ++G G AG+ AA+AAA+ + +++ + A GG A Sbjct: 29 DVVVIGGGHAGIEAALAAARMGAKTAMFVLNADTIGQMSCNPAIGGIA------------ 76 Query: 67 FHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGS-VNVRRFGGMKIERT 125 G + +++ G + D + + + K + Sbjct: 77 -----KG------------------IVVREIDALGGEMGKAIDQTGIQFKMLNTRKGKAV 113 Query: 126 WFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIR 185 + + + + + V+DI+V + V G+ V+ + Sbjct: 114 QSPRAQADKKRYREYMKKVCENQENLYIKQEEVVDIIVKNNQVVGV-----RTNLGVEYK 168 Query: 186 ANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVP 223 AVV+ TG NG I GD M G P Sbjct: 169 TKAVVVTTGTF-------LNGVIYIGDKMIPGGRLGEP 199 >5U63-A nrPDB Length = 321 Score = 34.0 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 11/72 (15%) Query: 3 TFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDS 62 A L I+G+G AG AAI AA+A N K L+ T +GG + ++ Sbjct: 7 IKHAKLLILGSGPAGYTAAIYAARA--NLKPVLV---------TGLQQGGQLTTTDEIEN 55 Query: 63 FEYHFHDTVAGG 74 + F T G Sbjct: 56 WPGDFEMTTGSG 67 >4AP1-A nrPDB Length = 549 Score = 33.2 bits (74), Expect = 0.32, Method: Composition-based stats. Identities = 33/213 (15%), Positives = 62/213 (29%), Gaps = 61/213 (28%) Query: 3 TFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDS 62 T D+ +VGAG AGL A + A G V Sbjct: 19 TTSYDVVVVGAGIAGLYAIHRFRSQGLTVR-------------AFEAASGVGGV------ 59 Query: 63 FEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKI 122 + ++ + C+ + +DY P + W ++ +P+ + Sbjct: 60 WYWNRYPGAR-----CDVESIDYSYSFSPELEQEW-NWSEKYATQPEILAYLE------- 106 Query: 123 ERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLV 182 AD+ + RFD +L ++G + + Sbjct: 107 ----HVADR-------------FDLRRDIRFDTRVTSAVLDEEG-----LRWTVRTDRGD 144 Query: 183 QIRANAVVMATGGAGRVYRYNTNGGIVTGDGMG 215 ++ A +V+A G +N DG+ Sbjct: 145 EVSARFLVVAAG-------PLSNANTPAFDGLD 170 >2GAG-B nrPDB Length = 405 Score = 33.2 bits (74), Expect = 0.34, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 19/39 (48%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSH 45 D IVG GG GL A A+ + +A++ K + + Sbjct: 23 DAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGN 61 >5MJK-A nrPDB Length = 327 Score = 33.2 bits (74), Expect = 0.35, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMR 43 D+ I+G+G AG+ AA+ A++ K L+ + P Sbjct: 26 DVVIIGSGPAGMTAAMYTARS--EMKTLLLERGVPGG 60 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Query: 338 AYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGEC 381 YVG+DPV E + G I TD + T I G+FAVG+ Sbjct: 255 IYVGLDPVAEFVSDL-GITDEAGWIITDDHMRTNIPGIFAVGDV 297 >5U8W-A nrPDB Length = 481 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 4/47 (8%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS 53 D+ ++GAG G AAI AAQ K A I K A GG+ Sbjct: 9 DVVVIGAGPGGYVAAIRAAQLG--LKTACIEKYIGKEG--KVALGGT 51 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 7/81 (8%) Query: 360 GGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELV-VFGRLAGEQAT-ERAAT 417 G I D +C+T + G+FA+G+ + GA L + E V V R+AG +A Sbjct: 302 GFIYVDDHCKTSVPGVFAIGDV----VRGA-MLAHKASEEGVMVAERIAGHKAQMNYDLI 356 Query: 418 AGNGNEAAIEAQAAGVEQRLK 438 A EQ LK Sbjct: 357 PSVIYTHPEIAWVGKTEQTLK 377 >2Q7V-A nrPDB Length = 325 Score = 32.8 bits (73), Expect = 0.38, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMR 43 D+ I+G G AGL AAI +A + ++ K P Sbjct: 10 DVVIIGGGPAGLTAAIYTGRAQLS--TLILEKGMPGG 44 >1F8S-A nrPDB Length = 498 Score = 32.8 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHT 46 + IVGAG AGL AA A A + S+ R T Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRT 74 >5TR3-A nrPDB Length = 481 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 3 TFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS 53 T + D+ ++GAG G AAI AAQ K A I K A GG+ Sbjct: 5 TQKFDVVVIGAGPGGYVAAIKAAQLG--LKTACIEKYTDAEG--KLALGGT 51 >2WOV-A nrPDB Length = 495 Score = 32.8 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 12/56 (21%) Query: 328 RLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSS 383 R+P +L VGV + GG++ D+ T + ++A+G+ + Sbjct: 290 RIPRTNDLQLGNVGVKLTPK------------GGVQVDEFSRTNVPNIYAIGDITD 333 >5J5Z-A nrPDB Length = 496 Score = 32.8 bits (73), Expect = 0.44, Method: Composition-based stats. Identities = 21/170 (12%), Positives = 51/170 (30%), Gaps = 22/170 (12%) Query: 360 GGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELV--VFGRLAGEQATERAAT 417 G I + +T+I ++A+G+ + + L + E + V G G + Sbjct: 322 GRIPVNTRFQTKIPNIYAIGDVVAGPM-----LAHKAEDEGIICVEGMAGGAVHIDYNCV 376 Query: 418 AGNGNEAAIEAQAAGVEQRLKD--LVNQDGGENWAK-------------IRDEMGLAMEE 462 A E++LK+ + + G +A ++ + + Sbjct: 377 PSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDR 436 Query: 463 GCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHG 512 G + + +++ A E + + L + Sbjct: 437 VLGAHILGPGAGEMVNEAALALEYGASCEVIARVCHAHPTLSEAFREANL 486 Score = 32.4 bits (72), Expect = 0.60, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 2 QTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSH 45 Q AD+ ++G+G G AAI AAQ K I K + Sbjct: 25 QPIDADVTVIGSGPGGYVAAIKAAQLG--FKTVCIEKNETLGGT 66 >5USX-A nrPDB Length = 319 Score = 32.4 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 11/59 (18%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSF 63 + L I+G+G AG AA+ AA+AN N + T +GG + +++ Sbjct: 6 HSKLLILGSGPAGYTAAVYAARANLNPVLI-----------TGMQQGGQLTTTTEVENW 53 >1HP1-A nrPDB Length = 516 Score = 32.4 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 26/151 (17%), Positives = 49/151 (32%), Gaps = 13/151 (8%) Query: 74 GDWLCEQDVVDYFVHHCPTEMT--QLELWGCPWSRRPDGSV-NVRRFGGMKIERTWFA-- 128 G ++D V + + + Q++ G ++ G + + G + + Sbjct: 335 GRLEGDRDKVRFVQTNMGRLILAAQMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQP 394 Query: 129 -------ADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTL 181 AD TG ++ L + P + + + + DG + L Sbjct: 395 FGNVVVYADMTGKEVIDYLTAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPA 454 Query: 182 VQIRANAVVM-ATGGAGRVYRYNTNGGIVTG 211 R + ATGG G N G + TG Sbjct: 455 KTYRMATLNFNATGGDGYPRLDNKPGYVNTG 485 >3NIX-A nrPDB Length = 421 Score = 32.4 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 19/40 (47%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVY 40 MQ + D+ ++GAG AG AA ++ KI K Sbjct: 1 MQREKVDVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKFP 40 >2YQU-A nrPDB Length = 455 Score = 32.4 bits (72), Expect = 0.54, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSH 45 DL ++GAG G AAI AAQ K+ ++ K + Sbjct: 3 DLLVIGAGPGGYVAAIRAAQLG--MKVGVVEKEKALGGT 39 >4JNQ-A nrPDB Length = 345 Score = 32.1 bits (71), Expect = 0.66, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 32/97 (32%), Gaps = 20/97 (20%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDH 60 M A + ++G+G AG AAI AA+A + +GG + D Sbjct: 22 MTQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVI-----------AGLQQGGQLMITTDV 70 Query: 61 DSF---------EYHFHDTVAGGDWLCEQDVVDYFVH 88 +++ + + + Q V D Sbjct: 71 ENYPGYAEPVQGPWMMEQMARQAENVGAQIVHDIITE 107 >2RGJ-A nrPDB Length = 402 Score = 32.1 bits (71), Expect = 0.73, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALIS 37 D+ I GAG GL A+A QA K+ L+ Sbjct: 6 DILIAGAGIGGLSCALALHQAGIG-KVTLLE 35 >2NVK-X nrPDB Length = 488 Score = 32.1 bits (71), Expect = 0.83, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 21/56 (37%), Gaps = 4/56 (7%) Query: 4 FQADLAIVGAGGAGLRAAIAAAQANPNAKIALIS--KVYPMRSHTVAAEGGSAAVA 57 + DL ++G G AGL A A A++A + K P G V Sbjct: 8 YDYDLIVIGGGSAGLACAKEAVLNG--ARVACLDFVKPTPTLGTKWGVGGTCVNVG 61 >4H7U-A nrPDB Length = 602 Score = 31.7 bits (70), Expect = 0.85, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 D + G G AGL A ++ N N K+ +I + V G A+ +++ Sbjct: 42 DFIVAGGGTAGLVVASRLSE-NSNWKVLVIEAGPSNKDAFVTRVPGLASTLGAGSPIDWN 100 Query: 67 F 67 + Sbjct: 101 Y 101 >3LAD-A nrPDB Length = 476 Score = 31.7 bits (70), Expect = 0.89, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 5/80 (6%) Query: 360 GGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQAT-ERAATA 418 G I D C T + G++A+G+ + GA S +VV R+AG +A Sbjct: 298 GFIYVDDYCATSVPGVYAIGDV----VRGAMLAHKASEEGVVVAERIAGHKAQMNYDLIP 353 Query: 419 GNGNEAAIEAQAAGVEQRLK 438 A EQ LK Sbjct: 354 AVIYTHPEIAGVGKTEQALK 373 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS 53 D+ ++GAG G AAI +AQ K ALI K T A GG+ Sbjct: 5 DVIVIGAGPGGYVAAIKSAQLG--LKTALIEKYKGKEGKT--ALGGT 47 >3CP2-A nrPDB Length = 649 Score = 31.7 bits (70), Expect = 0.94, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 64/192 (33%), Gaps = 43/192 (22%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 D+ I+G G AG AA+AAA+ + L++ H Sbjct: 28 DVIIIGGGHAGTEAAMAAARMGQ--QTLLLT----------------------------H 57 Query: 67 FHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTW 126 DT+ G C + H + +++ G ++ D + R Sbjct: 58 NIDTL--GQMSCNPAIGGIGKGH---LVKEVDALGGLMAKAIDQAGIQFRILNASKGPAV 112 Query: 127 FAADKTGFHML--HTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQI 184 A +L + P + F + V D++V++ V G V ++ Sbjct: 113 RATRAQADRVLYRQAVRTALENQPNLMIF-QQAVEDLIVENDRVVGAV-----TQMGLKF 166 Query: 185 RANAVVMATGGA 196 RA AVV+ G Sbjct: 167 RAKAVVLTVGTF 178 >3G05-A nrPDB Length = 576 Score = 31.7 bits (70), Expect = 0.98, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 64/192 (33%), Gaps = 43/192 (22%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 D+ I+G G AG AA+AAA+ + L++ H Sbjct: 34 DVIIIGGGHAGTEAAMAAARMGQ--QTLLLT----------------------------H 63 Query: 67 FHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTW 126 DT+ G C + H + +++ G ++ D + R Sbjct: 64 NIDTL--GQMSCNPAIGGIGKGH---LVKEVDALGGLMAKAIDQAGIQFRILNASKGPAV 118 Query: 127 FAADKTGFHML--HTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQI 184 A +L + P + F + V D++V++ V G V ++ Sbjct: 119 RATRAQADRVLYRQAVRTALENQPNLMIF-QQAVEDLIVENDRVVGAV-----TQMGLKF 172 Query: 185 RANAVVMATGGA 196 RA AVV+ G Sbjct: 173 RAKAVVLTVGTF 184 >3RP7-A nrPDB Length = 407 Score = 31.7 bits (70), Expect = 0.98, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 21/49 (42%), Gaps = 2/49 (4%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKI--ALISKVYPMRSHTVAAEG 51 ++GAG GL AA+A Q+ + + A+ + +V G Sbjct: 23 HMKAIVIGAGIGGLSAAVALKQSGIDCDVYEAVKEIKPVGAAISVWPNG 71 >5W1J-A nrPDB Length = 584 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 15/28 (53%) Query: 358 TMGGIETDQNCETRIKGLFAVGECSSVG 385 T G + D T + ++A+G+ S+ G Sbjct: 404 TNGRVVVDDEERTNVPNIYAIGDVSNAG 431 >4TXK-A nrPDB Length = 615 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 9 AIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTV 47 +VGAG GLRAA+ A A++ L+ K H V Sbjct: 88 LVVGAGPCGLRAAVELALLG--ARVVLVEKRIKFSRHNV 124 >2BRY-A nrPDB Length = 497 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 9 AIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTV 47 +VGAG GLRAA+ A A++ L+ K H V Sbjct: 96 LVVGAGPCGLRAAVELALLG--ARVVLVEKRIKFSRHNV 132 >5MOG-A nrPDB Length = 497 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 11/59 (18%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYH 66 + I GAG AGL A A A K L+ + GG A +D D +++ Sbjct: 20 VVIAGAGLAGLSTAKYLADAGH--KPILLEARDVL--------GGKIAAWKDEDG-DWY 67 >3IC9-A nrPDB Length = 492 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALIS 37 M+ D+AI+G G AG+ A AA+ + + K+ LI Sbjct: 4 MKVINVDVAIIGTGTAGM-GAYRAAKKHTD-KVVLIE 38 >1XDI-A nrPDB Length = 499 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 39/136 (28%), Gaps = 12/136 (8%) Query: 8 LAIVGAGGAGLRAAIAAAQANP-NAKIALISKVYPMR---------SHTVAAEGGSAAVA 57 + I+G G AG AA+ AA ++P ++ +I S T A G Sbjct: 5 IVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRTEL 64 Query: 58 QDHDSFEYHFH-DTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRR 116 + +H D V QL G ++ Sbjct: 65 RRAPHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELIDSTP 124 Query: 117 FGGMKIERTWFAADKT 132 G + AAD + Sbjct: 125 -GLARHRIKATAADGS 139 >4NBT-A nrPDB Length = 240 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHT 46 M+ + +A++ G GL AIA A A AK+ SH Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHP 46 >5APG-A nrPDB Length = 185 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 27/76 (35%), Gaps = 4/76 (5%) Query: 285 LGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDP 344 L P D+V E R + I V + + + K + RLP + + G Sbjct: 53 LTPSDRV----IAESRGLSLIDCSWKRAVDVHTKFIRGKFIRRRLPLLIAANPTHYGKPY 108 Query: 345 VKEPIPVRPTAHYTMG 360 + I A Y MG Sbjct: 109 ILSTIEAVAAALYIMG 124 >4NEW-A nrPDB Length = 492 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 15/23 (65%) Query: 360 GGIETDQNCETRIKGLFAVGECS 382 GG++ D+ T + ++A+G+ + Sbjct: 307 GGVQVDEYSRTNVSNIYAIGDVT 329 >2DKH-A nrPDB Length = 639 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 61/220 (27%), Gaps = 27/220 (12%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFE 64 Q D+ IVG G AGL A A + K PM + G A + Sbjct: 32 QVDVLIVGCGPAGLTLAAQLAAFPDIRTCIVEQKEGPME---LGQADGIACRTMEMFEAF 88 Query: 65 YHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIER 124 + W+ + G P G V G + Sbjct: 89 EFADSILKEACWINDVTF-------------WKPDPGQPGRIARHGRVQDTEDGLSEFPH 135 Query: 125 TWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGH----VRGLVAMN--MME 178 + H L + + + + VLD+ VD G V + Sbjct: 136 VILNQARVHDHYLERMRNSPSRL---EPHYARRVLDVKVDHGAADYPVTVTLERCDAAHA 192 Query: 179 GTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL 218 G + ++A VV G V R G + GD A Sbjct: 193 GQIETVQARYVVGCDGARSNVRRAI--GRQLVGDSANQAW 230 >4ZCC-A nrPDB Length = 336 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 22/46 (47%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS 53 +AI+G G AGL AA A A + S+ R + ++ GS Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAGS 50 >2CVJ-A nrPDB Length = 180 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 19/31 (61%), Gaps = 2/31 (6%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKIALIS 37 D+ +VG G +GL AA+ A+A K+ ++ Sbjct: 3 DVIVVGGGPSGLSAALFLARAG--LKVLVLD 31 >2JB2-A nrPDB Length = 489 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 2/46 (4%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS 53 + ++G G AGL +A +A K+ ++ A GGS Sbjct: 14 VVVLGGGPAGLCSAFELQKAG--YKVTVLEARTRPGGRVWTARGGS 57 >6BWT-A nrPDB Length = 319 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 25/67 (37%), Gaps = 9/67 (13%) Query: 133 GFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMA 192 G ++ L + + +F +D +D+ + G + Q + +++A Sbjct: 63 GPELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVG---------EVEQYTCDTLIIA 113 Query: 193 TGGAGRV 199 TG + Sbjct: 114 TGATAKY 120 >4C5O-A nrPDB Length = 357 Score = 30.5 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS 44 D+ ++G G +GL A ++ + + L ++ P + Sbjct: 3 SVDVVVIGGGQSGLSAGYFLRRSGLSY-VILDAEASPGGA 41 >3KKJ-A nrPDB Length = 336 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%) Query: 8 LAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGS 53 +AI+G G AGL AA A A + S+ R + ++ G+ Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGA 50 >3ARQ-A nrPDB Length = 584 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 10/27 (37%) Query: 172 VAMNMMEGTLVQIRANAVVMATGGAGR 198 N G L+ + V+A G + Sbjct: 513 WVWNRSTGELITFDDHRSVLAKGNYAK 539 >1EBD-A nrPDB Length = 455 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Query: 5 QADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMR 43 + + +VGAG G AAI AAQ K+ ++ K Sbjct: 3 ETETLVVGAGPGGYVAAIRAAQLGQ--KVTIVEKGNLGG 39 >4EMJ-A nrPDB Length = 410 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 4/40 (10%) Query: 361 GIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAEL 400 G+ D T KG+FAVG+ +S L R G E Sbjct: 256 GVIVDHCGATLAKGVFAVGDVASWPL----RAGGRRSLET 291 >2EQ6-A nrPDB Length = 464 Score = 29.7 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 4/43 (9%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMR 43 M+T+ DL ++G G G AAI AAQ K+ + Sbjct: 4 MKTY--DLIVIGTGPGGYHAAIRAAQLG--LKVLAVEAGEVGG 42 Score = 29.0 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 30/82 (36%), Gaps = 8/82 (9%) Query: 360 GGIETDQNCETRIKGLFAVGECSSVGL--HGANRLGSNSLAELVVFGRLAGEQATERAAT 417 G I + ET + G++A+G+ + L H A R G L+ AG+ + Sbjct: 289 GFIRVNARMETSVPGVYAIGDAARPPLLAHKAMREG------LIAAENAAGKDSAFDYQV 342 Query: 418 AGNGNEAAIEAQAAGVEQRLKD 439 + A E+ K Sbjct: 343 PSVVYTSPEWAGVGLTEEEAKR 364 >1C0L-A nrPDB Length = 363 Score = 29.7 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 22/49 (44%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAA 49 M Q + ++G+G GL +A+ A+ + I + S T A+ Sbjct: 2 MMHSQKRVVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFAS 50 >1F6M-A nrPDB Length = 320 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 11/61 (18%) Query: 3 TFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDS 62 T + L I+G+G AG AA+ AA+AN + T +GG + ++ Sbjct: 3 TKHSKLLILGSGPAGYTAAVYAARANLQPVLI-----------TGMEKGGQLTTTTEVEN 51 Query: 63 F 63 + Sbjct: 52 W 52 >5M43-A nrPDB Length = 225 Score = 29.4 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 21/54 (38%), Gaps = 4/54 (7%) Query: 311 DVVYLDLRHLGEKKLHERLPFICELAKAYV-GVDPVKEPIPVRPT---AHYTMG 360 + +D+ + ++ + LP I + + G+DP P H MG Sbjct: 53 KHLSIDIDDMEDQDILIHLPKIVRFIDSGLRGIDPSDSSAVASPGVVLVHCAMG 106 >5UTH-A nrPDB Length = 319 Score = 29.0 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 12/27 (44%), Positives = 17/27 (62%) Query: 7 DLAIVGAGGAGLRAAIAAAQANPNAKI 33 D+ I+G+G AG AAI AA+A + Sbjct: 17 DVIIIGSGPAGYTAAIYAARAQLKPLV 43 >4Y4M-A nrPDB Length = 290 Score = 28.6 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 1 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISK 38 + +AD+ IVGAG +GL A A+ K+ ++ + Sbjct: 55 LDIVEADVVIVGAGPSGLTCARYLAKEG--FKVVVLER 90 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.125 0.318 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,086,758 Number of Sequences: 36641 Number of extensions: 846257 Number of successful extensions: 2990 Number of sequences better than 10.0: 107 Number of HSP's better than 10.0 without gapping: 96 Number of HSP's successfully gapped in prelim test: 58 Number of HSP's that attempted gapping in prelim test: 2620 Number of HSP's gapped (non-prelim): 222 length of query: 602 length of database: 10,336,785 effective HSP length: 103 effective length of query: 499 effective length of database: 6,562,762 effective search space: 3274818238 effective search space used: 3274818238 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 62 (28.6 bits)