BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00326 (375 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1U3W-A nrPDB 757 0.0 1HSZ-A nrPDB 730 0.0 1HSO-A nrPDB 712 0.0 1EE2-A nrPDB 674 0.0 1D1T-A nrPDB 550 e-157 1MC5-A nrPDB 473 e-134 3COS-A nrPDB 459 e-130 1P0F-A nrPDB 441 e-124 1CDO-A nrPDB 423 e-119 1E3E-A nrPDB 414 e-116 4DLA-A nrPDB 400 e-112 4JJI-A nrPDB 394 e-110 4RQU-A nrPDB 388 e-108 5TNX-A nrPDB 202 2e-52 1F8F-A nrPDB 186 2e-47 3PII-A nrPDB 136 2e-32 4Z6K-A nrPDB 124 6e-29 3MEQ-A nrPDB 123 1e-28 5YLN-A nrPDB 114 5e-26 3S2F-A nrPDB 113 1e-25 4CPD-A nrPDB 110 8e-25 1LLU-A nrPDB 110 1e-24 4EEZ-A nrPDB 107 6e-24 6N7L-A nrPDB 100 8e-22 6FG0-A nrPDB 100 1e-21 1H2B-A nrPDB 100 1e-21 2DFV-A nrPDB 100 2e-21 2EER-A nrPDB 98 6e-21 4GKV-A nrPDB 96 2e-20 5VM2-A nrPDB 96 2e-20 2DQ4-A nrPDB 95 5e-20 3GFB-A nrPDB 94 1e-19 3TWO-A nrPDB 92 3e-19 1PL8-A nrPDB 92 3e-19 3QE3-A nrPDB 91 5e-19 4EJ6-A nrPDB 91 7e-19 2H6E-A nrPDB 91 8e-19 5K1S-A nrPDB 91 1e-18 5ENV-A nrPDB 91 1e-18 4OH1-A nrPDB 89 2e-18 1R37-A nrPDB 88 5e-18 4ILK-A nrPDB 87 9e-18 4UEJ-A nrPDB 87 2e-17 1YKF-A nrPDB 85 6e-17 4JLW-A nrPDB 84 7e-17 3FPL-A nrPDB 84 1e-16 5YAT-A nrPDB 82 3e-16 5KIA-A nrPDB 78 7e-15 1KOL-A nrPDB 76 2e-14 3WLE-A nrPDB 75 5e-14 2DPH-A nrPDB 74 8e-14 1UUF-A nrPDB 74 1e-13 3FPC-A nrPDB 72 3e-13 1KEV-A nrPDB 72 5e-13 3FSR-A nrPDB 71 7e-13 3IP1-A nrPDB 71 8e-13 5H82-A nrPDB 70 1e-12 1E3J-A nrPDB 69 4e-12 5VKT-A nrPDB 68 5e-12 6DKH-A nrPDB 67 9e-12 5Z0C-A nrPDB 67 1e-11 4OAQ-A nrPDB 64 8e-11 2OUI-A nrPDB 64 1e-10 2VCY-A nrPDB 63 3e-10 5FI5-A nrPDB 60 1e-09 3M6I-A nrPDB 59 3e-09 3UOG-A nrPDB 58 5e-09 1YQX-A nrPDB 58 8e-09 1WLY-A nrPDB 56 3e-08 2CDC-A nrPDB 54 1e-07 3QWB-A nrPDB 52 4e-07 1YB5-A nrPDB 52 5e-07 5H83-A nrPDB 50 1e-06 1QOR-A nrPDB 49 4e-06 1Q1N-A nrPDB 49 5e-06 3SLK-A nrPDB 46 2e-05 3B70-A nrPDB 44 8e-05 4A27-A nrPDB 44 1e-04 3JYN-A nrPDB 44 1e-04 3WID-A nrPDB 42 5e-04 3FBG-A nrPDB 39 0.004 6C49-A nrPDB 39 0.004 4RVS-A nrPDB 38 0.006 2WEK-A nrPDB 37 0.010 4IDE-A nrPDB 37 0.011 4Y1B-A nrPDB 37 0.017 3HZZ-A nrPDB 36 0.021 5A3V-A nrPDB 34 0.10 4DVJ-A nrPDB 34 0.10 4J6F-A nrPDB 34 0.11 2OBY-A nrPDB 33 0.27 4MMI-A nrPDB 32 0.53 3TQH-A nrPDB 32 0.62 6ACF-A nrPDB 31 0.71 2CF5-A nrPDB 31 1.0 3SMA-A nrPDB 30 1.2 4KPA-A nrPDB 30 1.5 5ILO-A nrPDB 30 1.6 1TWI-A nrPDB 30 2.2 6BKV-A nrPDB 30 2.4 1V9L-A nrPDB 29 3.3 1VJO-A nrPDB 29 3.5 4AJW-A nrPDB 29 4.0 2VN8-A nrPDB 29 4.1 2B25-A nrPDB 29 4.2 1V3V-A nrPDB 29 4.2 2VWH-A nrPDB 28 5.0 1JGT-A nrPDB 28 7.8 4A10-A nrPDB 28 9.1 >1U3W-A nrPDB Length = 374 Score = 757 bits (1954), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/374 (99%), Positives = 374/374 (100%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIG+LDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITN+LPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFD 360 Query: 362 LLRSGKSIRTVLTF 375 LLRSGKSIRTVLTF Sbjct: 361 LLRSGKSIRTVLTF 374 >1HSZ-A nrPDB Length = 374 Score = 730 bits (1884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/374 (94%), Positives = 366/374 (97%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVA GICR+D+HVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR+CKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTC GKPIHHF+G STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS VMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 300 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LSINPMLLLTGRTWKGA++GGFKSKE +PKLVADFMAKKFSLDALIT++LPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLRSGKSIRTVLTF 375 LL SGKSIRTVLTF Sbjct: 361 LLHSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 712 bits (1839), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/374 (92%), Positives = 359/374 (95%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVA GIC +D+HVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCRICKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 120 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTC KPIHHF+G+STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS +MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LS+NPMLLLTGRTWKGAI GGFKSKE VPKLVADFMAKKFSLDALIT++LPFEKINEGFD Sbjct: 301 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLRSGKSIRTVLTF 375 LL SGKSIRT+L F Sbjct: 361 LLHSGKSIRTILMF 374 >1EE2-A nrPDB Length = 373 Score = 674 bits (1740), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/374 (87%), Positives = 351/374 (93%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWE KKPFSIEEVEVAPPKAHEVRIKMVAAGICRSD+HVVSG LV P Sbjct: 1 STAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVI GHEAAGIVES+GEGVTTV+PGDKVIPLF PQCGKC +CK+PE N CLKN L PR Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKN-LSMPR 119 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GT+QDGT RFTC GKPIHHF+G STFSQYTVVDE +VAKIDAASPLEKVCL+GCGFSTGY Sbjct: 120 GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY 179 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVKVAKVT GSTCAVFGLGGVGLSV+MGCKAAGAARII VDINKDKFAKAKE+GATEC Sbjct: 180 GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 +NPQDYKKPIQEVL EM++GGVDFSFEVIGRLDTM+A+L CC EA G SVIVGVPPDSQN Sbjct: 240 VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN 299 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LS+NPMLLL+GRTWKGAIFGGFKSK+SVPKLVADFMAKKF+LD LIT++LPFEKINEGFD Sbjct: 300 LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD 359 Query: 362 LLRSGKSIRTVLTF 375 LLRSGKSIRT+LTF Sbjct: 360 LLRSGKSIRTILTF 373 >1D1T-A nrPDB Length = 373 Score = 550 bits (1416), Expect = e-157, Method: Compositional matrix adjust. Identities = 258/373 (69%), Positives = 313/373 (83%), Gaps = 1/373 (0%) Query: 3 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL 62 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GICR+D+HV+ G +V+ Sbjct: 2 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG 122 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ RG Sbjct: 62 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 120 Query: 123 TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 L DGT RFTC GKP+HHF+ STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 121 VLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 180 Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AVK KV PGSTC VFGLGGVGLSV+MGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 181 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 240 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ L Sbjct: 241 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 300 Query: 303 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDL 362 + +PMLL TGRTWKG +FGG KS++ VPKLV +F+AKKF LD LIT++LPF+KI+EGF+L Sbjct: 301 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 360 Query: 363 LRSGKSIRTVLTF 375 L SG+SIRTVLTF Sbjct: 361 LNSGQSIRTVLTF 373 >1MC5-A nrPDB Length = 374 Score = 473 bits (1216), Expect = e-134, Method: Compositional matrix adjust. Identities = 234/371 (63%), Positives = 290/371 (78%), Gaps = 1/371 (0%) Query: 4 AGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG-NLVTPL 62 A +VIKCKAAV WE KP SIEE+EVAPPKAHEVRIK++A +C +D + +SG + Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG 122 PVILGHE AGIVESVGEGVT +K GD VIPL+ PQCG+C+ C NP++N C K + +G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 123 TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + DGT RFTC GK I H++G STFS+YTVV + +VAKID +PL+KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AV AK+ PGS CAVFGLGGVGL+V+MGCK AGA+RII VDINKDKFA+AKE GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 NPQD+ KPIQEVL EMTDGGVD+SFE IG + M A+L CH+ G SV+VGV + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 303 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDL 362 + P L+TGRTWKG FGG+KS ESVPKLV+++M+KK +D +T+ L F++IN+ F+L Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 363 LRSGKSIRTVL 373 + SGKSIRTV+ Sbjct: 362 MHSGKSIRTVV 372 >3COS-A nrPDB Length = 381 Score = 459 bits (1181), Expect = e-130, Method: Compositional matrix adjust. Identities = 227/380 (59%), Positives = 284/380 (74%), Gaps = 5/380 (1%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV- 59 M T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C +D V+ Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 60 TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLK-NDLG 118 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K ++L Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 119 NP---RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 +P + ++D T RFTC GKP++HF G STFSQYTVV + +AKID + LE+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 176 GFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 GFSTGYG+A+ AKVTPGSTCAVFGLGGVGLS VMGCKAAGA+RII +DIN +KF KAK Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 296 PPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEK 355 S+ L++ P L+ GRT G FGG+KS +S+PKLV D+ KKF+LDAL+T+ LPF+K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 356 INEGFDLLRSGKSIRTVLTF 375 I+E FDL+ GKSIRT+L F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1P0F-A nrPDB Length = 373 Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust. Identities = 220/375 (58%), Positives = 287/375 (76%), Gaps = 2/375 (0%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60 M TAGK I CKAAV WE KP S+E + VAPPKAHEVRIK++A+GIC SD V+ + + Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 PVILGHEA G+VES+G GVT VKPGDKVIPLF PQCG CR CK+ SN+C KND+G Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + D T RFTC GKPI++ +G STF++YTVV + AVAKID +PLE CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AV AKVTPGSTCAVFGLGGVG S ++GCKAAGA+RII V +KDKF KA ELGATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 C+NP+DY KPI EV+ E T+GGVD++ E GR++TMM +L + G +V++G+ ++ Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360 L ++P+LLLTGR+ KG++FGGFK +E V +LV D+M KK +++ L++ L ++IN+ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKGEE-VSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 361 DLLRSGKSIRTVLTF 375 +LL SG+ +R+++ + Sbjct: 359 ELLSSGQGVRSIMIY 373 >1CDO-A nrPDB Length = 374 Score = 423 bits (1088), Expect = e-119, Method: Compositional matrix adjust. Identities = 205/375 (54%), Positives = 268/375 (71%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSD-EHVVSGNLVT 60 +T GKVIKCKAAV WE KP IEE+EV P A+E+RIK++A G+C +D H+ G Sbjct: 1 ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 PV+LGHE AGIVESVG GVT +PG+KVIPLF QCG+CR C++P++N C+K Sbjct: 61 GFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANES 120 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 + RFTC G+ + F+G STFSQYTVV++ AVAKID ++PL+ VCL+GCG STG Sbjct: 121 PDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTG 180 Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +G+AV AKV PGSTCAVFGLG VGL+ VMGC +AGA RIIAVD+N DKF KAK GAT+ Sbjct: 181 FGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATD 240 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 +NP D+ +PI +VL +MT+GGVDFS E +G + M +L C + G SV+VG D Sbjct: 241 FVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGW-TDLH 299 Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360 +++ P+ L+ GRTWKG++FGGFK K+ VPK+V ++ KK LD IT+ +P E +N+ Sbjct: 300 DVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAI 359 Query: 361 DLLRSGKSIRTVLTF 375 DL++ GK IRTVL+ Sbjct: 360 DLMKHGKCIRTVLSL 374 >1E3E-A nrPDB Length = 376 Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust. Identities = 204/377 (54%), Positives = 272/377 (72%), Gaps = 6/377 (1%) Query: 3 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL 62 T GKVIKCKAA+ W+ P IEE+EV+PPKA EVRI+++A +C +D + Sbjct: 2 TQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKALF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLK-NDLGNP- 120 PV+LGHE AGIVESVG GVT KPGDKVIP F PQC +C++C +P +N C K + P Sbjct: 62 PVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPT 121 Query: 121 --RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFS 178 + ++D T RFTC G+ I+HF+GVS+FSQYTVV E +A++D + LE+VCLIGCGFS Sbjct: 122 IDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFS 181 Query: 179 TGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGA 238 +GYG+A+ AKVTPGSTCAVFGLG VGLS ++GCK AGA+RIIA+DIN +KF KAK LGA Sbjct: 182 SGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGA 241 Query: 239 TECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298 T+C+NP++ KP+Q+V+ E+T GGVD+S + G T+ A++ C G+ +VG D Sbjct: 242 TDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVD 301 Query: 299 SQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINE 358 ++I + ++ GR+ G FGG+KS +SVP LV+D+ KKF LD L+T+ LPFE IN+ Sbjct: 302 --EMTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIND 359 Query: 359 GFDLLRSGKSIRTVLTF 375 DL++ GKSIRT+LTF Sbjct: 360 AIDLMKEGKSIRTILTF 376 >4DLA-A nrPDB Length = 396 Score = 400 bits (1029), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/374 (52%), Positives = 259/374 (69%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 +T G+VI CKAAV WE KP IE+V+VAPP+A EVR+K++ +C +D + SG Sbjct: 19 ATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEG 78 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 L P +LGHEAAGIVESVGEGVT V+PGD VIP + +C +C+ CK+ ++N C K Sbjct: 79 LFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATG 138 Query: 121 RGTL-QDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ +GKPI+HF+G STFSQYTVV + +VAKID +PLEKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ AKV PGS AVFGLG VGL+V G KAAGA+RII +DI+ KF +AK G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E INP+++++PIQ+V+ ++TDGGVD+SFE IG + M ++L CCH+ GTSVIVGV Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 Q +S P L+TGR WKG FGGFKS+ VP LV ++ K+ +D IT+ + IN+ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 360 FDLLRSGKSIRTVL 373 FDL+ G +R VL Sbjct: 379 FDLMHDGDCLRVVL 392 >4JJI-A nrPDB Length = 378 Score = 394 bits (1012), Expect = e-110, Method: Compositional matrix adjust. Identities = 199/374 (53%), Positives = 256/374 (68%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 +T G+VI CKAAV +E KP IE+V+VAPP+A EVRIK++ +C +D + SG Sbjct: 1 ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 60 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 L P ILGHEAAGIVESVGEGVT V+ GD VIP + +C +C+ CK+ ++N C K Sbjct: 61 LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 120 Query: 121 RG-TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ +GKPI+HF+G STFSQYTVV + +VAKID +PL+KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ AKV PGS A+FGLG VGL+V G K AGA+RII +DI+ K+ AK+ G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E +NP+D+ KPIQEV+ ++TDGGVD+SFE IG + M A+L CCH+ GTSVIVGV Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 Q +S P L+TGR WKG FGGFKS+ VP LV +M K+ +D IT+ L +IN+ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 360 FDLLRSGKSIRTVL 373 FDLL G +R VL Sbjct: 361 FDLLHEGTCLRCVL 374 >4RQU-A nrPDB Length = 375 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 186/372 (50%), Positives = 248/372 (66%), Gaps = 2/372 (0%) Query: 6 KVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL-PV 64 ++I+CKAAV WE KP IEEVEVAPP+ HEVRIK++ +C +D + TPL P Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG-T 123 I GHEA GIVESVGEGVT ++PGD V+P+FT +CG+CR C + ESN C + RG Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + DG RF+ +GKPI+HF+G STFS+YTVV VAKI+ +PL+KVC++ CG STG G+ Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 + VAK G + A+FGLG VGL G + AGA+RII VD N +F +AKE G TEC+N Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 P+D+ KPIQ+V+ EMTDGGVD S E G + M+ + C H+ G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 304 INPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLL 363 +PM L RT KG FG +K K +P +V +M K+ L+ IT+ +PF +IN+ FD + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 364 RSGKSIRTVLTF 375 G+SIR ++T Sbjct: 362 LKGESIRCIITM 373 >5TNX-A nrPDB Length = 383 Score = 202 bits (514), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 129/357 (36%), Positives = 188/357 (52%), Gaps = 10/357 (2%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEG 80 PFSIE + P+ EV +++VA G+C +D V PLP +LGHE AG+VE+VG Sbjct: 29 PFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVGPN 88 Query: 81 VTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG-TRRFTCSGKPIH 139 V T+ GD V+ L CG C C YC + N G DG T +G+P+H Sbjct: 89 VKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEPLH 147 Query: 140 -HFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAV 198 HF S+F+ Y + EN K+ +PLE + +GCG TG G+ + V GS+ A Sbjct: 148 DHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSFAS 207 Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 FG G VG+S VM + AGA IIAVDI + A A ELGAT IN ++ + + ++E+ Sbjct: 208 FGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIREI 265 Query: 259 TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNLSINPMLLLTGRTWK 316 T GGVD++ E G L +++ + + GT +VG P +N LLL G T + Sbjct: 266 TGGGVDYALESTG-LPAVLSQGIDALGSRGTMGVVGAPKLGTKAEFDVNS-LLLGGHTIR 323 Query: 317 GAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVL 373 G + G + +P+LV + +F D L+ P E+IN+ SG +++ +L Sbjct: 324 GIVEGDSVPQTFIPQLVQLHLQGRFPFDRLV-KFYPLEQINQAAADSSSGITLKPIL 379 >1F8F-A nrPDB Length = 371 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 118/356 (33%), Positives = 185/356 (51%), Gaps = 10/356 (2%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGV 81 F ++ +++ P+ EV +K+VA G+C +D V PLP +LGHE +GI+E++G V Sbjct: 19 FELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGSGIIEAIGPNV 78 Query: 82 TTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPI--H 139 T ++ GD V+ L CGKC C YC + N G +G + + Sbjct: 79 TELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQGVVND 137 Query: 140 HFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF 199 HF S+F+ Y + EN K+ P+E + +GCG TG G+ + KVTP S+ + Sbjct: 138 HFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALKVTPASSFVTW 197 Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G G VGLS ++ K GA+ IIAVDI + + AK+LGAT IN + + P+ + KE+T Sbjct: 198 GAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKT-QDPVAAI-KEIT 255 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNLSINPMLLLTGRTWKG 317 DGGV+F+ E G + + + G +VG P + +N LLL G+T G Sbjct: 256 DGGVNFALESTGSPEILKQGVDALG-ILGKIAVVGAPQLGTTAQFDVND-LLLGGKTILG 313 Query: 318 AIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVL 373 + G K+ +P+LV + KF D L+ F++IN+ R G +++ ++ Sbjct: 314 VVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGITLKPII 368 >3PII-A nrPDB Length = 339 Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 122/369 (33%), Positives = 168/369 (45%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTP-LPVILGH 68 KAAV+ + K+P I+EVE EV +++ A G+C +D H G+ V P LP+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E GIVE VG GVT +K GD+V IP CG C C + + C + G DG Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLC---EHQKNAGYSVDG 118 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 +++Y + V KI E+ I C T Y A+KV Sbjct: 119 G------------------YAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALKV 159 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A++G+GG G V KA G ++AVDI +K AKELGA +NP Sbjct: 160 TGAKPGEWVAIYGIGGFGHVAVQYAKAMG-LNVVAVDIGDEKLELAKELGADLVVNP--L 216 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 K+ + +KE GGV + V S G V+VG+PP+ + I Sbjct: 217 KEDAAKFMKEKV-GGVHAAV-VTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDT 274 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 +L G G+I G K + + A+ K I + P EKINE FD + G+ Sbjct: 275 -VLNGIKIIGSIVGTRKDLQEALQFAAEGKVKT------IIEVQPLEKINEVFDRMLKGQ 327 Query: 368 -SIRTVLTF 375 + R VLT Sbjct: 328 INGRVVLTL 336 >4Z6K-A nrPDB Length = 346 Score = 124 bits (311), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 112/361 (31%), Positives = 166/361 (45%), Gaps = 39/361 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPL-PVILGH 68 KAAVL E + IEEV++ P A E+ +KM A+G+C +D H V G+ V P P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G++ +VGEGVT VK GD+V + CG C C C Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQ----------- 110 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 ++ +G +F++Y + + N V I + ++ + C T Y +K+ Sbjct: 111 NSGYSVNG----------SFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKM 159 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G V A G + AVDI+ DK A AK+LGA +N ++ Sbjct: 160 TDTKPGDWVVISGIGGLGHMAVQYAIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKN- 217 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 P + + KE+ V + S+L GT V G+PP +SI Sbjct: 218 TDPAEYLQKEIGGAHGALVTAVSAKAFDQALSML---RRGGTLVCNGLPPGDFPVSIFDT 274 Query: 308 LLLTGRTWKGAIFGG-FKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 +L G T +G+I G +ES+ MA + A +T P E IN+ F+ +R G Sbjct: 275 -VLNGITIRGSIVGTRLDLQESLD------MAAAGKVKATVT-AEPLENINDIFERMRQG 326 Query: 367 K 367 K Sbjct: 327 K 327 >3MEQ-A nrPDB Length = 365 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 114/361 (31%), Positives = 159/361 (44%), Gaps = 37/361 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTP-LPVILGH 68 KAAV+ KP +I+EV + P ++++ + A+G+C +D H G+ V P P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GV VK GD+V IP CG CR C C + L G Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQ--------LNTG 138 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 ++ +G F++Y V D N V + ++ + C T Y +KV Sbjct: 139 ---YSVNGG----------FAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGLKV 184 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G V +A G + AVDI+ K A+ LGAT +N + Sbjct: 185 TDTKPGDWVVISGIGGLGHMAVQYARAMG-LNVAAVDIDDRKLDLARRLGATVTVNAKTV 243 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 P + KE TDGG V L GT + G+PP LSI M Sbjct: 244 ADPAAYIRKE-TDGGAQGVL-VTAVSPKAFEQALGMVARGGTVSLNGLPPGDFPLSIFNM 301 Query: 308 LLLTGRTWKGAIFGG-FKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 +L G T +G+I G +ES+ DF A + T L E IN FD +R G Sbjct: 302 -VLNGVTVRGSIVGTRLDLQESL-----DFAADGKVKATIQTGKL--EDINAIFDDMRQG 353 Query: 367 K 367 Sbjct: 354 N 354 >5YLN-A nrPDB Length = 356 Score = 114 bits (286), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 100/355 (28%), Positives = 164/355 (46%), Gaps = 41/355 (11%) Query: 20 KPFSIEEVEVAPP---KAHEVRIKMVAAGICRSDEHVVSGNLVT-PLPVILGHEAAGIVE 75 KP V+V P K + +++V IC +D H++ G++ T ILGHE GIVE Sbjct: 12 KPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEGIGIVE 71 Query: 76 SVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSG 135 VGEGV+ K GDKV+ CGKC CK +C +++ G G L DG + Sbjct: 72 EVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHC-EDEGGWIFGHLIDGMQ------ 124 Query: 136 KPIHHFVGVSTFSQYTVV--DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 193 ++Y V +N + E + ++ TGY V KV PG Sbjct: 125 ------------AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPG 172 Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + A+ G G VGL+ ++ + A++I VD++ ++ A GAT +N D +K I+E Sbjct: 173 CSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKE 232 Query: 254 VLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN--PMLLL 310 + ++TDG GVD + E +G + A+ C + I+GV N ++ P+ Sbjct: 233 IY-DLTDGRGVDVAIEAVG----IPATFDFCQK------IIGVDGTVANCGVHGKPVEFD 281 Query: 311 TGRTWKGAI--FGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLL 363 + W I G S + P+L+ + K + L+T+ +I + +++ Sbjct: 282 LDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVF 336 >3S2F-A nrPDB Length = 340 Score = 113 bits (283), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 110/370 (29%), Positives = 161/370 (43%), Gaps = 40/370 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTP-LPVILGH 68 KAAV+ P +I+EV V P +V++K+ A+G+C +D H G+ V P LP I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GV+ VK GD+V +P CG C C C K Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQ----------- 112 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 ++ +G + +Y V D N V + ++ I C T Y +KV Sbjct: 113 NTGYSVNGG----------YGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKV 161 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G V +A G R+ AVDI+ K A+ LGA +N +D Sbjct: 162 TDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARD- 219 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 P + KE+ G V + + GT + G+PP I Sbjct: 220 TDPAAWLQKEI---GGAHGVLVTAVSPKAFSQAIGMVRRGGTIALNGLPPGDFGTPIFD- 275 Query: 308 LLLTGRTWKGAIFGGFKS-KESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 ++L G T +G+I G +ES+ DF A + A ++ + +N+ F LR G Sbjct: 276 VVLKGITIRGSIVGTRSDLQESL-----DFAAHG-DVKATVST-AKLDDVNDVFGRLREG 328 Query: 367 K-SIRTVLTF 375 K R VL F Sbjct: 329 KVEGRVVLDF 338 >4CPD-A nrPDB Length = 347 Score = 110 bits (276), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 98/372 (26%), Positives = 166/372 (44%), Gaps = 40/372 (10%) Query: 13 AVLWELKKPFSIEEVEVAPPKAH--EVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEA 70 AV++E K+ +++EV AP H + +++ AGIC SD H+ G + +LGHE Sbjct: 3 AVVFENKERVAVKEVN-APRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHEF 61 Query: 71 AGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDL-------GNPRGT 123 G VE+VGEG+ ++PGD V+ F CG C C+ + N C + + GN +G Sbjct: 62 VGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQGA 121 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + R FS + K+ E+ G ST YG Sbjct: 122 QAEILR---------------VPFSNVN------LRKLPPNLSPERAIFAGDILSTAYGG 160 Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 ++ ++ PG + AV G G VGL + + GA++I+A+D ++ +A LGA IN Sbjct: 161 LIQ-GQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-IN 218 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 + + P++ V E D G D E +G T+ +L G VGV N Sbjct: 219 AEQ-ENPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPG-GRVSAVGV----DNAP 272 Query: 304 INPMLLLTGRTWKGAIFGGFKSKE-SVPKLVADFMAKKFSLDALITNILPFEKINEGFDL 362 P L +G G + + ++A + + + ++++ LP E+ G++L Sbjct: 273 SFPFPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYEL 332 Query: 363 LRSGKSIRTVLT 374 ++++ +L Sbjct: 333 FDRKEALKVLLV 344 >1LLU-A nrPDB Length = 342 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 99/363 (27%), Positives = 158/363 (43%), Gaps = 43/363 (11%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN--LVTPLPVILGH 68 KAAV+ P IEEV+V P +V +K+ A+G+C +D H G+ + PLP I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GVT VK GD+V IP CG C C C Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQ----------- 116 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 ++ +G +++Y + D N V + ++ I C T Y +K Sbjct: 117 NTGYSVNGG----------YAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGLKQ 165 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A+ G+GG+G V +A G + A+DI+ K A++LGA+ +N + Sbjct: 166 TNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVNARQ- 223 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 + P++ + +++ G V ++ + GT +VG+PP I Sbjct: 224 EDPVEAIQRDI---GGAHGVLVTAVSNSAFGQAIGMARRGGTIALVGLPPGDFPTPIFD- 279 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALI-TNILP--FEKINEGFDLLR 364 ++L G G+I G + A F+ + L+ I P + IN+ D +R Sbjct: 280 VVLKGLHIAGSIVGTRADLQE---------ALDFAGEGLVKATIHPGKLDDINQILDQMR 330 Query: 365 SGK 367 +G+ Sbjct: 331 AGQ 333 >4EEZ-A nrPDB Length = 348 Score = 107 bits (268), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 109/372 (29%), Positives = 169/372 (45%), Gaps = 42/372 (11%) Query: 11 KAAVLWELKKPFS-IEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHE 69 KAAV+ ++ + E E+ K +E + M G+C +D HV +G+ +LGHE Sbjct: 2 KAAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHE 61 Query: 70 AAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGT 128 GIV+ +G V++++ GD+V + F CG C C + +C Sbjct: 62 GIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFC---------------- 105 Query: 129 RRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA 188 R +G + V + VV + AV D P+E I C T Y A+KV+ Sbjct: 106 REVKNAG----YSVDGGMAEEAIVVADYAVKVPDGLDPIE-ASSITCAGVTTY-KAIKVS 159 Query: 189 KVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 V PG +FG GG+G + K A++IAVDIN+DK AK++GA IN D Sbjct: 160 GVKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDV- 218 Query: 249 KPIQEVLKEMTDG-GVDFSFE-VIGRL--DTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304 P+ E+ K++T G GV + + R+ + +ASL + G V V VP LS+ Sbjct: 219 NPVDEI-KKITGGLGVQSAIVCAVARIAFEQAVASL----KPMGKMVAVAVPNTEMTLSV 273 Query: 305 NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364 P ++ G G++ G + A+ K I E+IN+ D ++ Sbjct: 274 -PTVVFDGVEVAGSLVGTRLDLAEAFQFGAEGKVKP------IVATRKLEEINDIIDEMK 326 Query: 365 SGK-SIRTVLTF 375 +GK R V+ F Sbjct: 327 AGKIEGRMVIDF 338 >6N7L-A nrPDB Length = 353 Score = 100 bits (250), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 105/368 (28%), Positives = 156/368 (42%), Gaps = 54/368 (14%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT--PLPVILGH 68 KAAV+ +P I+EV V P +EV +K++A G+C +D H V G+ +P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E GIV + G VK GD V +P CG C C C G G DG Sbjct: 75 EGVGIVVACGPD-AMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNG---GYSVDG 130 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 F++Y + D V + + ++ I C T Y +K Sbjct: 131 ------------------GFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGLKE 171 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 + PG A+ G+GG+G V KA G + A+D+ DK AK+LGA +N + Sbjct: 172 TETKPGEWVAISGIGGLGHVAVQYAKAMG-MHVAAIDVADDKLELAKKLGADLTVNAK-- 228 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL--------LCCHEACGTSVIVGVPPDS 299 TD G EV G ++ ++ + GT + G+PP S Sbjct: 229 ----------TTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGS 278 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 L I +L T +G+I G K + DF A + + A +T+ E IN+ Sbjct: 279 FELPIFETVLKR-ITVRGSIVGTRKDLQE----ALDF-ANEGLVKATVTS-AKLEDINDV 331 Query: 360 FDLLRSGK 367 FD ++ G+ Sbjct: 332 FDKMKKGQ 339 >6FG0-A nrPDB Length = 352 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 80/273 (29%), Positives = 122/273 (44%), Gaps = 28/273 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVV---SGNLVTPLPVILG 67 KA E+ + ++ P E+ +K+ AAG+C SD V+ + LP+ LG Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKN-DLG-NPRGTLQ 125 HE G V +GEGVT GD V CG C C NYC + DLG P G Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGY-- 119 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTGYGSA 184 G P + ++Y +VD + I P+ L G + + + Sbjct: 120 ---------GSP-------GSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAIS 163 Query: 185 VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 + + PGST V G+GG+G + +A AAR+IAVD++ D+ A A+E+GA + Sbjct: 164 RVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKS 223 Query: 245 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM 276 + ++E+T G G F+ +G T+ Sbjct: 224 ---GAGAADAIRELTGGQGATAVFDFVGAQSTI 253 >1H2B-A nrPDB Length = 359 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 101/379 (26%), Positives = 179/379 (47%), Gaps = 46/379 (12%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAH-EVRIKMVAAGICRSDEHVVSG---NLVTP- 61 V + KAA L E KP IE+V+ + +V +++ AG+C +D H+V G L+ P Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LP LGHE G +E V EGV ++ GD VI G C C+ E +C +L P Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHC--ENLEFPG 130 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVC----LIGCGF 177 + G F+++ +V K+ EK+ L G Sbjct: 131 LNIDGG-------------------FAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGI 171 Query: 178 STGYGSAVKVAK-VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 T Y + K A+ + PG+ A+ G+GG+G V K A +IA+D+ ++K A+ L Sbjct: 172 -TAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERL 230 Query: 237 GATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 GA ++ + + P+++V+ E+T G GV+ + + +G T+ + G +IVG Sbjct: 231 GADHVVDAR--RDPVKQVM-ELTRGRGVNVAMDFVGSQATVDYTPYLLGR-MGRLIIVGY 286 Query: 296 PPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEK 355 + + +I ++ + +++G++ G + + +LV + K ++ +I ++ Sbjct: 287 GGELRFPTIR--VISSEVSFEGSLVGNYV---ELHELVTLALQGKVRVE---VDIHKLDE 338 Query: 356 INEGFDLLRSGKSI-RTVL 373 IN+ + L G+ + R VL Sbjct: 339 INDVLERLEKGEVLGRAVL 357 >2DFV-A nrPDB Length = 347 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 100/361 (27%), Positives = 159/361 (44%), Gaps = 45/361 (12%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN-----LVTPLPVILGHEAAGIVESVGEG 80 EV+V P EV IK++A IC +D H+ N + P P I+GHE AG V +G G Sbjct: 20 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP-PQIMGHEVAGEVVEIGPG 78 Query: 81 VTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHH 140 V ++ GD V CGKC C+ + + C + G DG Sbjct: 79 VEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKI---FGVDTDG------------- 122 Query: 141 FVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP--GSTCAV 198 F++Y VV + K + P E L G+AV P G + + Sbjct: 123 -----VFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPISGKSVLI 172 Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G G +GL + KA+GA +I + + + AK++GA INP +++ + + + ++ Sbjct: 173 TGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINP--FEEDVVKEVMDI 230 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKG 317 TDG GVD E G + L A G ++G+ P + N +++ T Sbjct: 231 TDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTIDFNNLIIFKALT--- 286 Query: 318 AIFG--GFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRSGKSIRTVLT 374 I+G G E+ + + K +LD +IT+ F+K E F+L+R+GK+ + V Sbjct: 287 -IYGITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFM 345 Query: 375 F 375 Sbjct: 346 L 346 >2EER-A nrPDB Length = 347 Score = 97.8 bits (242), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 103/378 (27%), Positives = 161/378 (42%), Gaps = 49/378 (12%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG---------NLVTP 61 +A L E+ KP +E++ + PK +V IK+ AAG+C SD H+ G +L Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C +PR Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC-----DSPR 116 Query: 122 --GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFS 178 G DG +++Y +V + K+ S +E L G + Sbjct: 117 WLGINYDG------------------AYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVT 158 Query: 179 TGYGSAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 T AV+ A + P T V G GG+G + KA A II VD+ ++ AK G Sbjct: 159 T--YRAVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAG 216 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 A IN + P+ E+ + G D ++ T+ + G V+VG+ Sbjct: 217 ADYVINASS-QDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQ-GKYVMVGL-- 272 Query: 298 DSQNLSIN-PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKI 356 +L + P++ L + G++ G + L A+ + ++T + E+ Sbjct: 273 FGADLKYHAPLITLNEVQFIGSLVGNQSDFLGIMSL-----AEAGKVKPMVTKTMKLEEA 327 Query: 357 NEGFDLLRSGKSI-RTVL 373 NE D L + K++ R VL Sbjct: 328 NEAIDNLENFKAVGRQVL 345 >4GKV-A nrPDB Length = 336 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 92/292 (31%), Positives = 136/292 (46%), Gaps = 32/292 (10%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-I 91 K E +KM G+C +D HV +G+ VILGHE G+V VG GVT++KPGD+ + Sbjct: 23 KHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASV 82 Query: 92 PLFTPQCGKCRICKNPESNYC--LKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQ 149 F CG C C + C +KN G DG C + Sbjct: 83 AWFYEGCGHCEYCNSGNETLCRSVKN-----AGYSVDGGMAEEC-----------IVVAD 126 Query: 150 YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV 209 Y V + + A+S I C T Y AVK++K+ PG A++GLGG+G + Sbjct: 127 YAVKVPDGLDSAAASS-------ITCAGVTTY-KAVKLSKIRPGQWIAIYGLGGLGNLAL 178 Query: 210 MGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV 269 K A++IA+D+N ++ A E+GA IN + + ++++E T G + V Sbjct: 179 QYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTEDAAKIVQEKTGGAH--AAVV 234 Query: 270 IGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFG 321 S + A G V VG+PP+S +L I P L+L G G++ G Sbjct: 235 TAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLVLDGIEVVGSLVG 285 >5VM2-A nrPDB Length = 347 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 97/358 (27%), Positives = 149/358 (41%), Gaps = 46/358 (12%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEH-VVSGNLVTP----LPVILGHE 69 + ++ I E+ PK EV IK+ GIC SD H SG + P + LGHE Sbjct: 7 ILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHE 66 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDL----GNPRGTLQ 125 AG V +VG V KPGD+V CG CR C + N C D N RG L Sbjct: 67 CAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALT 126 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 H+ +F+ Y + D + P + G +A+ Sbjct: 127 -------------HYLCHPESFT-YKLPDNMDTMEGTLVEPA----------AVGMHAAM 162 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-- 243 +A V PG + G G +GL + CK GA I VD+ + + A A++LGAT IN Sbjct: 163 -LADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGA 221 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 +D Q+ ++M G D FE G T+ + G +IVG P + + Sbjct: 222 KEDTIARCQQFTEDM---GADIVFETAGSAVTVKQAPYLVMRG-GKIMIVGTVPGAS--A 275 Query: 304 INPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 IN + + T + F+ P + + +F + +++T+I + + + F+ Sbjct: 276 INFLKINREVTIQTV----FRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >2DQ4-A nrPDB Length = 343 Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 92/354 (25%), Positives = 152/354 (42%), Gaps = 43/354 (12%) Query: 29 VAPPKAHEVRIKMVAAGICRSDEHVVSGNL-----VTPLPVILGHEAAGIVESVGEGVTT 83 V P E+ +++ AA IC +D H+ + + P P++ GHE +G+VE+VG GV Sbjct: 20 VPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRP-PLVTGHEFSGVVEAVGPGVRR 78 Query: 84 VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVG 143 + GD V C C C+ + CL + G +DG Sbjct: 79 PQVGDHVSLESHIVCHACPACRTGNYHVCLNTQI---LGVDRDG---------------- 119 Query: 144 VSTFSQYTVVDENAVAKIDAASPLEKVCLI---GCGFSTGY-GSAVKVAKVTPGSTCAVF 199 F++Y VV P E ++ G T Y GS V G + + Sbjct: 120 --GFAEYVVVPAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVS------GKSVLIT 171 Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G G +GL M +A+GA I+ D N + A A+ A +NP ++ + EV++ +T Sbjct: 172 GAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP--LEEDLLEVVRRVT 228 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAI 319 GV+ E G + L+ G + I+G+P D + L++ G T G Sbjct: 229 GSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIPSDPIRFDLAGELVMRGITAFG-- 285 Query: 320 FGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVL 373 G + ++ + A + + L L+T+ LP + E F LL SG++++ +L Sbjct: 286 IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASGQAVKVIL 339 >3GFB-A nrPDB Length = 350 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 97/357 (27%), Positives = 155/357 (43%), Gaps = 41/357 (11%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN-----LVTPLPVILGHEAAGIVESVGEG 80 EV+V P EV IK++A IC +D H+ N + P P I+GHE AG V VG G Sbjct: 21 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP-PQIMGHEVAGEVVEVGPG 79 Query: 81 VTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHH 140 V ++ GD + CGKC CK+ + C + G DG Sbjct: 80 VEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKI---FGVDMDG------------- 123 Query: 141 FVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP--GSTCAV 198 F+ Y +V K P E L G+AV P G + + Sbjct: 124 -----VFAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGRSTLI 173 Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G G +GL + KA+GA +I + ++ + AK++GA +NP + + P++ V+ ++ Sbjct: 174 TGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVKFVM-DI 231 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKG 317 TDG GV+ E G + L G ++G+ P + N +++ G Sbjct: 232 TDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFPREVTIDFNNLIIFKALEVHG 290 Query: 318 AIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRSGKSIRTVL 373 G E+ + + + K +LD +IT+ F+K E F+L+R+GK+ + V Sbjct: 291 --ITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >3TWO-A nrPDB Length = 348 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 90/323 (27%), Positives = 139/323 (43%), Gaps = 45/323 (13%) Query: 17 ELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL-PVILGHEAAGIVE 75 E KP V P +V I ++ AGIC SD H + P+I GHE AGI++ Sbjct: 15 EHFKPHDFSRHAVGP---RDVLIDILYAGICHSDIHSAYSEWKEGIYPMIPGHEIAGIIK 71 Query: 76 SVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCS 134 VG+GV K GD V + F C C+ CK + +C K + C Sbjct: 72 EVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKV------------VFTYDCL 119 Query: 135 GKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGS 194 + + +S VVDEN V +D +PLEKV + C T Y S +K +KVT G+ Sbjct: 120 DSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTY-SPLKFSKVTKGT 178 Query: 195 TCAVFGLGGVG-----LSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYK 248 V G GG+G +V MG + + AR N+ K A +G +P+ K Sbjct: 179 KVGVAGFGGLGSMAVKYAVAMGAEVSVFAR------NEHKKQDALSMGVKHFYTDPKQCK 232 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNLSINP 306 + + ++ + +++ L + + G +VG+PP + LS+ Sbjct: 233 EELDFIISTIPT-----HYDLKDYLKLLTYN--------GDLALVGLPPVEVAPVLSVFD 279 Query: 307 MLLLTGRTWKGAIFGGFKSKESV 329 + L R G++ GG K + + Sbjct: 280 FIHLGNRKVYGSLIGGIKETQEM 302 >1PL8-A nrPDB Length = 356 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 95/364 (26%), Positives = 159/364 (43%), Gaps = 47/364 (12%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESV 77 +E + P +EV ++M + GIC SD H GN + P++LGHEA+G VE V Sbjct: 19 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 78 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137 G V +KPGD+V + G R +ND G F C+ P Sbjct: 79 GSSVKHLKPGDRV----AIEPGAPR-----------ENDEFCKMGRYNLSPSIFFCATPP 123 Query: 138 ----IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 193 + F + Y + D + PL S G A + VT G Sbjct: 124 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLG 172 Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE Sbjct: 173 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQE 230 Query: 254 VLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 309 + +++ +G + + + E G ++ A + GT V+VG+ ++ P+L Sbjct: 231 IARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVLVGL---GSEMTTVPLLH 285 Query: 310 LTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSI 369 R I G F+ + P ++ +K ++ L+T+ P EK E F+ + G + Sbjct: 286 AAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 343 Query: 370 RTVL 373 + +L Sbjct: 344 KIML 347 >3QE3-A nrPDB Length = 355 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 94/361 (26%), Positives = 163/361 (45%), Gaps = 41/361 (11%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESV 77 +E + P +EV +KM + GIC SD H G+ V P++LGHEA+G V V Sbjct: 18 LRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKV 77 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137 G V ++PGD+V Q G R +++ K N T+ F C+ P Sbjct: 78 GSLVRHLQPGDRV----AIQPGAPR-----QTDEFCKIGRYNLSPTI------FFCATPP 122 Query: 138 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCA 197 ++ + N K+ E+ LI S G A + A VT G+ Sbjct: 123 DD-----GNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGI-HACRRAGVTLGNKVL 175 Query: 198 VFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-----NPQDYKKPIQ 252 V G G +GL ++ KA GAA+++ D++ + +KAKE+GA + +P++ K ++ Sbjct: 176 VCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVE 235 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTG 312 +L + + E G ++ A + H GT V+VG+ + ++ L+ Sbjct: 236 GLLGSKP----EVTIECTGVETSIQAGIYATHSG-GTLVLVGLGSEMTSVP-----LVHA 285 Query: 313 RTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTV 372 T + I G F+ + P ++ +K ++ L+T+ P EK E F+ + G ++ + Sbjct: 286 ATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVM 345 Query: 373 L 373 + Sbjct: 346 I 346 >4EJ6-A nrPDB Length = 370 Score = 90.9 bits (224), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 96/346 (27%), Positives = 148/346 (42%), Gaps = 32/346 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAG 72 AV E S+ V + P ++ +K+ A GIC +D H++ G + PV LGHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 IV G V + PG ++ CG+C C+ N C R Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLC----------------RNLR 129 Query: 133 CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP 192 G IH G F++Y +V +I L+ V C V ++ + Sbjct: 130 AIG--IHRDGG---FAEYVLVPRKQAFEIPLT--LDPVHGAFCEPLACCLHGVDLSGIKA 182 Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKP 250 GST A+ G G +GL V + AGA +I K A+E+GAT ++P D + Sbjct: 183 GSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEA 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 I + + GGVD E G +T+ S +A GT VI+GV P + + I P +L Sbjct: 243 IAGPVG-LVPGGVDVVIECAGVAETVKQSTRLA-KAGGTVVILGVLPQGEKVEIEPFDIL 300 Query: 311 TGRTWKGAIFGGFKSKESVPKLVADFMAK-KFSLDALITNILPFEK 355 R + + G F + V + AD +A +D +I+ + ++ Sbjct: 301 F-RELR--VLGSFINP-FVHRRAADLVATGAIEIDRMISRRISLDE 342 >2H6E-A nrPDB Length = 344 Score = 90.9 bits (224), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 102/374 (27%), Positives = 169/374 (45%), Gaps = 52/374 (13%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP---LP 63 ++K KAA+L + +P SIE+V + P+ EV I++ AG+CR+D V G LP Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGT 123 +ILGHE AG + VGE + VK GD V+ T CR C+ + N C KN + P T Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC-KNQI-IPGQT 117 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENA-VAKIDAASPLEKVCLIGCGFSTGYG 182 G FS+Y +V + + K+++ SP+E L G +T G Sbjct: 118 TNGG-------------------FSEYMLVKSSRWLVKLNSLSPVEAAPLADAG-TTSMG 157 Query: 183 S---AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAK--AKELG 237 + A+ V G+GG+ + + KA I V I++ K + A ELG Sbjct: 158 AIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKAL-MKNITIVGISRSKKHRDFALELG 216 Query: 238 ATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM--MASLLCCHEACGTSVIVG 294 A +D + ++ ++TDG G + +++G +T + LL G ++VG Sbjct: 217 ADYVSEMKD----AESLINKLTDGLGASIAIDLVGTEETTYNLGKLLAQE---GAIILVG 269 Query: 295 VPPDSQNLSINPM-LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPF 353 + + + +S+ + + G+ +G E V +L K + + +P Sbjct: 270 M--EGKRVSLEAFDTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIK------VPL 321 Query: 354 EKINEGFDLLRSGK 367 + IN+ F L G+ Sbjct: 322 DDINKAFTNLDEGR 335 >5K1S-A nrPDB Length = 362 Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 96/348 (27%), Positives = 150/348 (43%), Gaps = 44/348 (12%) Query: 11 KAAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILG 67 KA VL + +E + + P EV +++ A G+C D GNL T +P ILG Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 HEAAG V VG K GD+ L CG C +C++ ++ C ++ Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDN----------- 127 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 RF P ++Q+ V + ++ A+ P + + C T + Sbjct: 128 --RFFGEELP-------GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTR 178 Query: 188 AKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ- 245 KV G T + G GGVGLS V + G AR+IAV ++ K KE GA E I + Sbjct: 179 GKVRAGETVLITGASGGVGLSSVQLARLDG-ARVIAVTSSEAKVQALKEAGADEVIVSRG 237 Query: 246 -DYKKPIQEVLKEMTDGGVDFSFEVIGR--LDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 D+ +V K GVD + E++G D + S+ A G V+V +S + Sbjct: 238 LDFAS---DVRKRTQGAGVDVAVEIVGSATFDQTLKSM-----APGGRVVVVGNLESGMV 289 Query: 303 SINPMLLLTGRTWKGAIFGGFKSKES----VPKLVADFMAKKFSLDAL 346 +NP L++ I G + + ++ +L A ++F DA+ Sbjct: 290 QLNPGLVIVKEL---EILGAYATTQAELDEALRLTATGGVRQFVTDAV 334 >5ENV-A nrPDB Length = 347 Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 86/294 (29%), Positives = 125/294 (42%), Gaps = 29/294 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGH 68 K + +E +++ V PKA+E+ I + +G+C +D H G+ P LP++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E AG+V +GE V K GD I C C C+ + C DL G DG Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADL---SGYTHDG 123 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 +F QY D A I + L +V I C T Y A+K Sbjct: 124 ------------------SFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKS 164 Query: 188 AKVTPGSTCAVFG-LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG+G V KA G R++ +D + K + +G I+ Sbjct: 165 ANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTK 223 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 K + VLK TDGG V + AS A GT+V+VG+P ++ Sbjct: 224 EKDIVGAVLK-ATDGGAHGVINVSVSEAAIEASTRYV-RANGTTVLVGMPAGAK 275 >4OH1-A nrPDB Length = 351 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 118/255 (46%), Gaps = 38/255 (14%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-------VTPLPVILGHEAAGIVESVG 78 E + PK E+RIK+V A IC SD H+++GNL + LP+ GHE +G+++ VG Sbjct: 25 EAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVIDKVG 84 Query: 79 EGVTTV--KPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGK 136 + K G KV+ + CG C C+ + N C +++G + +G Sbjct: 85 STAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLC--SNMG------------YRMNG- 129 Query: 137 PIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTC 196 FS+Y V + + I + L+ L+ + SA + AK++ G + Sbjct: 130 ----------FSEYAVYHMSQIFPIPDDADLKDYALVEP-LTVALSSAEQ-AKISYGKSV 177 Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 A+ G GG+G+ +V + AGA+ I DI +K A E GA +N + + + E Sbjct: 178 AIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EGVAERAI 235 Query: 257 EMTDGGVDFSFEVIG 271 E+ G D E G Sbjct: 236 ELAGGRYDCVLEGTG 250 >1R37-A nrPDB Length = 347 Score = 88.2 bits (217), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 104/378 (27%), Positives = 165/378 (43%), Gaps = 49/378 (12%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG---------NLVTP 61 +A L E+ KP S++E+ V PK +V IK+ AAG+C SD H+ G +L Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C +PR Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC-----DSPR 116 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVS---TFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGF 177 ++G++ +++Y +V + K+ + +E L G Sbjct: 117 -------------------WLGINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGI 157 Query: 178 STGYGSAVKVAKVTPGSTCAVFGLGGVGLSV-VMGCKAAGAARIIAVDINKDKFAKAKEL 236 +T AV+ A + P T V G GG ++ V KA A II VD+ ++ AK Sbjct: 158 TT--YRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRA 215 Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 GA IN + P+ E+ + GVD ++ T+ + G V+VG+ Sbjct: 216 GADYVINA-SMQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQ-GKYVMVGLF 273 Query: 297 PDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKI 356 + P++ L+ + G++ G + +L A+ + +IT + E+ Sbjct: 274 GADLHYHA-PLITLSEIQFVGSLVGNQSDFLGIMRL-----AEAGKVKPMITKTMKLEEA 327 Query: 357 NEGFDLLRSGKSI-RTVL 373 NE D L + K+I R VL Sbjct: 328 NEAIDNLENFKAIGRQVL 345 >4ILK-A nrPDB Length = 359 Score = 87.4 bits (215), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 108/251 (43%), Gaps = 35/251 (13%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG-NLVTPLPVILGHEAA 71 ++L E SI E E+ P A EVR+K+ AGIC SD H+ G N P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G++++VGEGV + + G++V CG C C + N C + G DG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADG---- 135 Query: 132 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIG----CGFSTGYGSAVKV 187 FS+Y VV KI A + +I TG+G Sbjct: 136 --------------GFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQP--- 178 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAA-GAARIIAVDINKDKFAKAKELGATECINPQD 246 T T V+G G +GL++V K +I D ++ KAKE GA IN + Sbjct: 179 ---TENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--N 233 Query: 247 YKKPIQEVLKE 257 + P+ E E Sbjct: 234 SQTPLGESFAE 244 >4UEJ-A nrPDB Length = 346 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/226 (29%), Positives = 102/226 (45%), Gaps = 28/226 (12%) Query: 36 EVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV--IPL 93 EVR+K+ ++G+C SD + N P+ LGHE +G +++VG GV + PGD V +PL Sbjct: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 Query: 94 FTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVV 153 C C C + C K D G+ +DG F++Y VV Sbjct: 87 LP--CFTCPECLKGFYSQCAKYDF---IGSRRDG------------------GFAEYIVV 123 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 V + P+E I + G A +A+ + G G +GL + Sbjct: 124 KRKNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAV 181 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 258 A GA + A+DI+ +K A AK GA + N + P +Q VL+E+ Sbjct: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 >1YKF-A nrPDB Length = 352 Score = 84.7 bits (208), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 99/349 (28%), Positives = 154/349 (44%), Gaps = 34/349 (9%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 E E P + ++ +A C SD H V G + +ILGHEA G V VG V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 85 KPGDKVI-PLFTPQCGKCRICK--NPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 KPGD+V+ P TP + + + S L G ++DG Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLA---GWKFSNVKDGV------------- 119 Query: 142 VGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL 201 F D N +A + PLE +I +TG+ A ++A + G+T AV G+ Sbjct: 120 --FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVLGI 175 Query: 202 GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 G VGL V G K GA RIIAV AK GAT+ +N +D PI+ + +T+G Sbjct: 176 GPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEG 233 Query: 262 -GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRTWKG 317 GVD + G D +MA+ + + GT V + + L + + + +T KG Sbjct: 234 KGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKG 292 Query: 318 AIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 + G + + + +L+ K+ L+T++ F+ I + F L++ Sbjct: 293 GLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >4JLW-A nrPDB Length = 399 Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 69/204 (33%), Positives = 97/204 (47%), Gaps = 8/204 (3%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 H V +++V+ IC SD+H+V G P ++LGHE G V +G GV T+K GD V F Sbjct: 35 HGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEITGEVVEIGRGVETMKIGDLVSVPF 94 Query: 95 TPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVD 154 CG CR CK + CL + G G+ + V + F+ + + Sbjct: 95 NVACGHCRTCKEQHTGVCLTVNPARAGGAYGYVDMGGWVGGQAEYVLVPYADFNLLKLPN 154 Query: 155 -ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 E A+ KI + L + TGY AV A V PGST + G G VGL+ + Sbjct: 155 REAAMEKIRDLTCLSDI------LPTGYHGAV-TAGVGPGSTVYIAGAGPVGLAAAASAR 207 Query: 214 AAGAARIIAVDINKDKFAKAKELG 237 GAA +I D+N + A AK+ G Sbjct: 208 LLGAAVVIVGDVNPTRLAHAKKQG 231 >3FPL-A nrPDB Length = 351 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 103/345 (29%), Positives = 154/345 (44%), Gaps = 42/345 (12%) Query: 34 AHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI- 91 +++ ++ +A C SD H V G L +ILGHEA G V VG V KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIV 83 Query: 92 PLFTPQCGKCRICK--NPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQ 149 P TP + SN L G +DG F + Sbjct: 84 PCTTPDWRSLEVQAGFQQHSNGMLA---GWKFSNFKDGV------------------FGE 122 Query: 150 YTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLS 207 Y V++ +A + PLE +I +TG+ A ++A + G+T AV G+G VGL Sbjct: 123 YFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAVLGIGPVGLM 181 Query: 208 VVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFS 266 V G K GA RIIAV AK GAT+ +N +D PI+ + +T+G GVD + Sbjct: 182 AVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEGKGVDAA 239 Query: 267 FEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL----LTGRTWKGAIF-G 321 G D +MA+ + + GT V + + L + P L + +T KG + G Sbjct: 240 IIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPV-PRLEWGCGMAHKTIKGGLCPG 297 Query: 322 GFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 G E + +V + + L L+T++ F+ I E L++ Sbjct: 298 GRLRAEMLRDMV---VYNRVDLSKLVTHVYHGFDHIEEALLLMKD 339 >5YAT-A nrPDB Length = 350 Score = 82.4 bits (202), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 74/245 (30%), Positives = 108/245 (44%), Gaps = 26/245 (10%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN--LVTPLPVILGHEAAGIVESVG 78 P +++ V PK++E+ I + +G+C +D H G+ L LP++ GHE AG+V + G Sbjct: 20 PLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGHEGAGVVVAYG 79 Query: 79 EGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137 E VT + GD I C C C + C K DL G DG Sbjct: 80 ENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADL---SGFTHDG---------- 126 Query: 138 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCA 197 +F QY D A+I + L +V I C T Y A+K A + G A Sbjct: 127 --------SFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALKTADLRIGQWVA 177 Query: 198 VFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 257 + G GG S+ + A R++ +D DK K LGA ++ K + EV K Sbjct: 178 ISGAGGGLGSLAVQYAKALGLRVLGIDGGADKGEFVKSLGAEVFVDFTKTKDVVAEVQK- 236 Query: 258 MTDGG 262 +T+GG Sbjct: 237 LTNGG 241 >5KIA-A nrPDB Length = 351 Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 82/347 (23%), Positives = 149/347 (42%), Gaps = 38/347 (10%) Query: 35 HEVRIKMVAAGICRSDEHVVSGN----LVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV 90 ++V IK+ IC +D H+ + P+P+ +GHE G + +G+ V GD+V Sbjct: 34 NDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRV 93 Query: 91 IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQY 150 CG CR C+ + C R T+ G R + ++ + F+ + Sbjct: 94 SGEGHITCGFCRNCRAGRRHLC--------RNTVGVGVNREGAFAE----YLAIPAFNAF 141 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 + E + + + I F +A+ V G + G G +G+ V Sbjct: 142 KIPPEIS----------DDLAAIFDPFGNATHTALSFNLV--GEDVLITGAGPIGVMAVA 189 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE--MTDGGVDFSFE 268 K GA ++ DIN + A+ +GAT +N ++ +++V+ + MT+ G D E Sbjct: 190 IAKHVGARNVVITDINDYRLDLARRMGATRAVNVS--RESLRDVMADLHMTE-GFDVGLE 246 Query: 269 VIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKES 328 + G + + SLL G ++G+PP + N ++ G KG G + E+ Sbjct: 247 MSG-VPSAFTSLLESMNHGGKVALLGIPPAQTAIDWN-QVIFKGLEIKGIY--GREMFET 302 Query: 329 VPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTF 375 K+VA + L +IT+ + +GF + SG+S + +L + Sbjct: 303 WYKMVA-MLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDW 348 >1KOL-A nrPDB Length = 398 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 8/204 (3%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 H V +K+V+ IC SD+H+V G + ++LGHE G V G V ++ GD V F Sbjct: 34 HGVILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPF 93 Query: 95 TPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVD 154 CG+CR CK + CL + G G+ + V + F+ + D Sbjct: 94 NVACGRCRSCKEMHTGVCLTVNPARAGGAYGYVDMGDWTGGQAEYVLVPYADFNLLKLPD 153 Query: 155 EN-AVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 + A+ KI + L + TGY AV A V PGST V G G VGL+ + Sbjct: 154 RDKAMEKIRDLTCLSDI------LPTGYHGAV-TAGVGPGSTVYVAGAGPVGLAAAASAR 206 Query: 214 AAGAARIIAVDINKDKFAKAKELG 237 GAA +I D+N + A AK G Sbjct: 207 LLGAAVVIVGDLNPARLAHAKAQG 230 >3WLE-A nrPDB Length = 341 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 90/313 (28%), Positives = 141/313 (45%), Gaps = 35/313 (11%) Query: 25 EEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 ++ V PKA ++ +K+ A G+C SD HV+ L ++GHE AG V +VG+ V Sbjct: 27 NDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINY 86 Query: 85 KPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGV 144 K GD+V + CG C+ C+ N C KN G+ G DG ++ V Sbjct: 87 KVGDRVACVGPNGCGGCKYCRGAIDNVC-KNAFGDWFGLGYDGG---------YQQYLLV 136 Query: 145 STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGV 204 + + + +N A + AAS + T Y A+K+A+V+P S + G GG+ Sbjct: 137 TRPRNLSRIPDNVSADVAAASTDAVL--------TPY-HAIKMAQVSPTSNILLIGAGGL 187 Query: 205 GLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G + + KA G A++ +D K+ +AK+LGA + E L E G Sbjct: 188 GGNAIQVAKAFG-AKVTVLDKKKEARDQAKKLGADA----------VYETLPESISPG-- 234 Query: 265 FSFEVIGRLDTMMASLLCCHEACG-TSVIVGVPPDSQNLSIN-PMLLLTGRTWKGAIFGG 322 SF ++ A+ C + VI+ V + NLS N L L G+ +G Sbjct: 235 -SFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGDLALREIRILGSFWGT 293 Query: 323 FKSKESVPKLVAD 335 + V KLV++ Sbjct: 294 TNDLDDVLKLVSE 306 >2DPH-A nrPDB Length = 398 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 91/306 (29%), Positives = 124/306 (40%), Gaps = 29/306 (9%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 H V +K+V+ IC SD+H+ G + P +LGHE G V G V + GD V F Sbjct: 33 HAVILKVVSTNICGSDQHIYRGRFIVPKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPF 92 Query: 95 TPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVD 154 CG+CR CK S+ C +N+L NP L G F G G + + D Sbjct: 93 NVACGRCRNCKEARSDVC-ENNLVNPDADL--GAFGFDLKGWS----GGQAEYVLVPYAD 145 Query: 155 ENAVAKIDAASPLEKV---CLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMG 211 + D +EK+ LI TG+ V A V PGS + G G VG G Sbjct: 146 YMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVS-AGVKPGSHVYIAGAGPVGRCAAAG 204 Query: 212 CKAAGAARIIAVDINKDKFAKAKELG--ATECINPQDYKKPIQEVL-KEMTDGGVD-FSF 267 + GAA +I D N ++ + G + N + I ++L K D GVD F Sbjct: 205 ARLLGAACVIVGDQNPERLKLLSDAGFETIDLRNSAPLRDQIDQILGKPEVDCGVDAVGF 264 Query: 268 EVIGRLDT--------MMASLLCCHEACGT----SVIVGVPPDSQNLSINP--MLLLTGR 313 E G D + SL A G + VG PD N + L G+ Sbjct: 265 EAHGLGDEANTETPNGALNSLFDVVRAGGAIGIPGIYVGSDPDPVNKDAGSGRLHLDFGK 324 Query: 314 TWKGAI 319 W +I Sbjct: 325 MWTKSI 330 >1UUF-A nrPDB Length = 369 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 100/379 (26%), Positives = 156/379 (41%), Gaps = 50/379 (13%) Query: 8 IKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV-TPLPVIL 66 +K KA + K+P ++ P ++V+I++ G+C SD H V T P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG+ V PGD V + C C C++ NYC Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYC----------DHM 130 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIG---CGFSTGYG 182 GT +P H G +SQ VV E V +I P E++ + C T Y Sbjct: 131 TGTYNSPTPDEPGHTLGG---YSQQIVVHERYVLRI--RHPQEQLAAVAPLLCAGITTY- 184 Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGA--ARIIAVDINKDKFAKAKELGATE 240 S ++ + PG V G+G MG K A A A ++A ++ K AK LGA E Sbjct: 185 SPLRHWQAGPGKKVGVV---GIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADE 241 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIG---RLDTMMASLLCCHEACGTSVIVGVPP 297 +N ++ + + LK DF + LD L + GT +VG P Sbjct: 242 VVNSRNADE-MAAHLKSF-----DFILNTVAAPHNLDDFTTLL----KRDGTMTLVGAPA 291 Query: 298 DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNI--LPFEK 355 L++ R G++ GG + + DF A+ ++ +I + ++ Sbjct: 292 TPHKSPEVFNLIMKRRAIAGSMIGGIPETQE----MLDFCAEH----GIVADIEMIRADQ 343 Query: 356 INEGFD-LLRSGKSIRTVL 373 INE ++ +LR R V+ Sbjct: 344 INEAYERMLRGDVKYRFVI 362 >3FPC-A nrPDB Length = 352 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 104/245 (42%), Gaps = 29/245 (11%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 E E P + ++ +A C SD H V G + +ILGHEA G V VG V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 85 KPGDKVI-PLFTPQCGKCRICK--NPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 KPGD+V+ P TP + + + S L G ++DG Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLA---GWKFSNVKDGV------------- 119 Query: 142 VGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL 201 F D N +A + PLE +I +TG+ A ++A + G T V G+ Sbjct: 120 --FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVIGI 175 Query: 202 GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMT 259 G VGL V G GA RI AV K A E GAT+ IN YK ++++LK Sbjct: 176 GPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIIN---YKNGDIVEQILKATD 232 Query: 260 DGGVD 264 GVD Sbjct: 233 GKGVD 237 >1KEV-A nrPDB Length = 351 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 73/237 (30%), Positives = 104/237 (43%), Gaps = 29/237 (12%) Query: 34 AHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI- 91 +++ ++ +A C SD H V G L +ILGHEA G V VG V KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIV 83 Query: 92 PLFTPQCGKCRICK--NPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQ 149 P TP + SN L G +DG F + Sbjct: 84 PCTTPDWRSLEVQAGFQQHSNGMLA---GWKFSNFKDGV------------------FGE 122 Query: 150 YTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLS 207 Y V++ +A + PLE +I +TG+ A ++A + GS+ V G+G VGL Sbjct: 123 YFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVVIGIGAVGLM 181 Query: 208 VVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 + G K GA RII V AK GAT+ +N ++ + +V+K GVD Sbjct: 182 GIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGKGVD 237 >3FSR-A nrPDB Length = 352 Score = 71.2 bits (173), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 104/243 (42%), Gaps = 25/243 (10%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 E E P + ++ +A C SD H V G + +ILGHEA G V VG V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 85 KPGDKVI-PLFTPQCGKCRICK--NPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 KPGD+V+ P TP + + + S L G ++DG Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLA---GWKFSNVKDGV------------- 119 Query: 142 VGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL 201 F D N +A + PLE +I +TG+ A ++A + GS+ V G+ Sbjct: 120 --FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVIGI 175 Query: 202 GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 G VGL + G K GA RII V AK GAT+ +N ++ + +V+K Sbjct: 176 GAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGK 234 Query: 262 GVD 264 GVD Sbjct: 235 GVD 237 >3IP1-A nrPDB Length = 404 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 60/376 (15%) Query: 24 IEEV-EVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTP----LPVILGHEAAGIV 74 +EEV E K E+ IK+ A GIC SD H+ G ++ P PV LGHE +G+V Sbjct: 44 VEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSGVV 103 Query: 75 ESVGEGVTTVKP------GDKVIPLFTPQCGKCRICKNPESNYCLK-NDLGNPRGTLQDG 127 G + G+ V CG CR C N+C N+LG Sbjct: 104 VEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELG--------- 154 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDEN---AVAKIDAASPLEKVCLIGCGF---STGY 181 F G F++Y VD ++ +++ +++ L G S Y Sbjct: 155 ---FNVDG----------AFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAY 201 Query: 182 GSA-VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 + V+ + PG + G G +GL+ V K AGA+++I + ++ + AKELGA Sbjct: 202 NAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADH 261 Query: 241 CINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASL-LCCHEACGTSVIVGVPPD 298 I+P K+ E + + T+G G E G + + A G + V + Sbjct: 262 VIDPT--KENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVAR 319 Query: 299 SQNLSINPMLLLTGRTW---KGAIFG--GFKSKESVPKLVADFMAKKFSLDALITNILPF 353 + + + LTG + + I G G + P++++ MA + +I+ + Sbjct: 320 A-----DAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTVSM 373 Query: 354 EKINEGFDLLRSGKSI 369 E+I E L++ KS+ Sbjct: 374 EEIPEYIKRLQTDKSL 389 >5H82-A nrPDB Length = 389 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 91/342 (26%), Positives = 140/342 (40%), Gaps = 33/342 (9%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 H+V+ K++ G+C D T P + GHE GIV +G V K GDKV + Sbjct: 54 HDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVGVG 113 Query: 93 LFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVG-------VS 145 F CGKC C YC P+ DGT F+ ++ V Sbjct: 114 NFIGSCGKCERCNEGLEPYC-------PKVIYTDGT-AFSDENNTVYGDVSGDGEDRIYG 165 Query: 146 TFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVG 205 +S V +E V + PL I CG Y PG + V G G +G Sbjct: 166 GYSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIG 225 Query: 206 LSVVMGCKAAGA-ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 V KA GA +I+ I+K + A K I+ K+P + E T G+ Sbjct: 226 KLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLIS----KEPEEMKAAESTLDGI- 280 Query: 265 FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFK 324 F+ + + + LL + GT V++GV ++ L ++P LL+ R + G+I G K Sbjct: 281 --FDCVPSV-HPLHPLLNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMK 336 Query: 325 SKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 + + DF AK + + ++P + +N + + G Sbjct: 337 ETQE----MLDFAAKHNIVSDI--ELIPMDYVNTALERIAKG 372 >1E3J-A nrPDB Length = 352 Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 63/210 (30%), Positives = 95/210 (45%), Gaps = 27/210 (12%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSD----EHVVSGNLVTPLPVILG 67 +AVL++ + +E+ + PK EV ++M GIC SD EH + + P+++G Sbjct: 7 SAVLYK-QNDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 HEA+G V VG+ V +K GD+V C +C+ CK + N C P T Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLC-------PDLTF--- 115 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 C+ P ++Y V + K+ LE+ L+ S G A + Sbjct: 116 -----CATPPDD-----GNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGV-HACRR 163 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGA 217 A V G+T V G G +GL V+ KA GA Sbjct: 164 AGVQLGTTVLVIGAGPIGLVSVLAAKAYGA 193 >5VKT-A nrPDB Length = 362 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 53/167 (31%), Positives = 72/167 (43%), Gaps = 20/167 (11%) Query: 36 EVRIKMVAAGICRSDEHVVSGNLVTPL-PVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V IK++ GIC +D HV+ + PV+ GHE G+V VG GVT K GD V + Sbjct: 36 DVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGDTVGVGY 95 Query: 94 FTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVST---FSQY 150 F C C C NYC DL T +G HH G +T FS Sbjct: 96 FVDSCRTCESCSTGHENYC--PDL------------VLTSNGVDHHHH-GATTKGGFSDV 140 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCA 197 VV ++ V ++ + PL+ + C T Y + A PG Sbjct: 141 LVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPGKHLG 187 >6DKH-A nrPDB Length = 346 Score = 67.4 bits (163), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 80/326 (24%), Positives = 131/326 (40%), Gaps = 34/326 (10%) Query: 39 IKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 +++ GIC SD H GN + P++LGHE G V + + + G V Sbjct: 35 VQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINP 92 Query: 95 TPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVD 154 + CG C+ C N C D+ RF S H G F++Y +V+ Sbjct: 93 SKPCGHCKYCIEHNENQC--TDM------------RFFGSAMYFPHVDG--GFTRYKMVE 136 Query: 155 ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKA 214 + A + EKV + +A + ++ G + G+G +G +V K Sbjct: 137 TSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVKT 194 Query: 215 AGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLD 274 GAA I+ D++ + KE+GA +NPQ+ + K G D SFEV G Sbjct: 195 LGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEK----GYFDVSFEVSGHPS 250 Query: 275 TMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVA 334 ++ L A G V VG+ ++ PM+ L G+ + ++ G F+ V+ Sbjct: 251 SVNTCLEVT-RARGVMVQVGM---GGAMAEFPMMTLIGK--EISLRGSFRFTSEFNTAVS 304 Query: 335 DFMAKKFSLDALITNILPFEKINEGF 360 + L++ PF + E Sbjct: 305 WLANGVINPLPLLSAEYPFTDLEEAL 330 >5Z0C-A nrPDB Length = 374 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 92/313 (29%), Positives = 126/313 (40%), Gaps = 40/313 (12%) Query: 36 EVRIKMVAAGICRSDEHVVSGNLV-TPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V K++ GIC SD H + T P + GHE G V VG V K GDKV + Sbjct: 40 DVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGC 99 Query: 94 FTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVV 153 C C C N NYC P L G+R + + ++H +S VV Sbjct: 100 IVGSCHSCPNCNNHLENYC-------PNRILTFGSRYYDGT---LNH----GGYSDLMVV 145 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 E+ +I A PL+ + C T Y PG V GLGG+G V K Sbjct: 146 QEHFAVRIPDALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAK 205 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 A G + K LGA I D ++ +Q + M G + Sbjct: 206 AFGVKVTVVSTSPAKKEDAISGLGAHSFILSTDAEQ-MQAAVGTMD-----------GII 253 Query: 274 DTMMAS-----LLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTW-KGAIFGGFKSKE 327 DT+ AS L+ ++ G V+VG PP L + P+LL GR G+ GG K + Sbjct: 254 DTVSASHPLPPLISLLKSHGKLVMVGDPPKPLELPVFPLLL--GRKMVAGSAIGGMKETQ 311 Query: 328 SVPKLVADFMAKK 340 + DF AK+ Sbjct: 312 E----MIDFAAKE 320 >4OAQ-A nrPDB Length = 367 Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 77/342 (22%), Positives = 133/342 (38%), Gaps = 34/342 (9%) Query: 16 WELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLP---VILGHEAAG 72 W K S E ++ P H+V +K G+C SD H +S PL +++GHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGW-QPLQRDNLVVGHEIIG 75 Query: 73 IVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 V +VG+ VT K GD+V I + C C+ C + YC + G + Sbjct: 76 EVIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYC------------KQGAATY 123 Query: 132 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVT 191 +++V +S +++ DE V I P + C T + ++ + Sbjct: 124 NSKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLD 183 Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G + + A A + A + K +A +LGA + + + K Sbjct: 184 ARGKNVGIIGIGGLGHLALQFANAMGANVTAFSRSSSKKEQAMKLGAHDFVATGEDKTWY 243 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTM-MASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 + D DF +D + ++ L + V VG+PP ++P L Sbjct: 244 KNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTFL 298 Query: 311 TGRTWKGAIFGG--FKSKESVPKLVADFMAKKFSLDALITNI 350 +GA FG SK V +++ +A K ++ +I + Sbjct: 299 Q----QGASFGSSLLGSKTEVKEMLN--LAAKHNVRPMIEEV 334 >2OUI-A nrPDB Length = 360 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 73/232 (31%), Positives = 106/232 (45%), Gaps = 29/232 (12%) Query: 39 IKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI-PLFTP 96 ++ +A C SD H V +G + +ILGHEA G + VG V +K GDKVI P TP Sbjct: 29 VRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITP 88 Query: 97 QCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDEN 156 G+ + + Y + + G L G +F+ + FS+ V+E Sbjct: 89 DWGE----EESQRGYPMHSG-----GML--GGWKFSNFKDGV--------FSEVFHVNEA 129 Query: 157 --AVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKA 214 +A + E ++ +TG+ A ++A + G T V G+G VGL V G Sbjct: 130 DANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDTVCVIGIGPVGLMSVAGANH 188 Query: 215 AGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264 GA RI AV K A E GAT+ IN YK ++++LK GVD Sbjct: 189 LGAGRIFAVGSRKHCCDIALEYGATDIIN---YKNGDIVEQILKATDGKGVD 237 >2VCY-A nrPDB Length = 344 Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 65/249 (26%), Positives = 103/249 (41%), Gaps = 60/249 (24%) Query: 20 KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN--LVTPLPVILGHEAAGIVESV 77 K ++ +E+A + +VR+KM+AA I SD +++ GN L+ LP + G+E V +V Sbjct: 27 KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAV 86 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137 G VT +KPGD VIP +N Sbjct: 87 GSNVTGLKPGDWVIP----------------AN--------------------------- 103 Query: 138 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG-STC 196 G+ T+ V E A+ ++ + PL+ +G T Y + ++ PG S Sbjct: 104 ----AGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 159 Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAV----DINK--DKFAKAKELGATECINPQDYKKP 250 GVG +V+ A G I V DI K D+ K LGA I ++ ++P Sbjct: 160 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRL---KSLGAEHVITEEELRRP 216 Query: 251 -IQEVLKEM 258 ++ K+M Sbjct: 217 EMKNFFKDM 225 >5FI5-A nrPDB Length = 357 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 78/311 (25%), Positives = 119/311 (38%), Gaps = 48/311 (15%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 H+V++K++ G C+ D + T P +LGHE G V VG V K GDKV + Sbjct: 43 HDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVGVA 102 Query: 93 LFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTV 152 CGKC +C N NYC P D S V Sbjct: 103 SIIETCGKCEMCTNEVENYC-------PEAGSIDSN---------------YGACSNIAV 140 Query: 153 VDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGC 212 ++EN V + PL+ + C T Y + PG + GLGG+G + Sbjct: 141 INENFVIRWPENLPLDSGVPLLCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFA 200 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECI---NPQDYKKPIQEVLKEMTDGGVDFSFEV 269 KA GA + K K ++ GA + NP++ + G +D Sbjct: 201 KAFGAKVTVISSSLKKKREAFEKFGADSFLVSSNPEEMQG---------AAGTLD----- 246 Query: 270 IGRLDTM-----MASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFK 324 G +DT+ + LL + G +I+G P + P LL+ G+ + G K Sbjct: 247 -GIIDTIPGNHSLEPLLALLKPLGKLIILGAPEMPFEVPA-PSLLMGGKVMAASTAGSMK 304 Query: 325 SKESVPKLVAD 335 + + + A+ Sbjct: 305 EIQEMIEFAAE 315 >3M6I-A nrPDB Length = 363 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 62/230 (26%), Positives = 99/230 (43%), Gaps = 34/230 (14%) Query: 15 LWELKKPFSIEEVEVAPP-KAHEVRIKMVAAGICRSDEHVVSGNLVTPLPV----ILGHE 69 LW + S+E V+ K EV + + + GIC SD H + P+ V +LGHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQ--CGKCRICKNPESNYCLKND-LGNPRGTLQD 126 +AG V +V V ++K GD+V PQ C C C N C + D L P + Sbjct: 80 SAGEVIAVHPSVKSIKVGDRV--AIEPQVICNACEPCLTGRYNGCERVDFLSTP--PVPG 135 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 RR+ H +G ++ +++ +VA + ++ Sbjct: 136 LLRRYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQ 173 Query: 187 VAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 A V G + G G +GL ++ KAAGA ++ DI++ + AKE+ Sbjct: 174 RAGVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEI 223 >3UOG-A nrPDB Length = 363 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 70/268 (26%), Positives = 113/268 (42%), Gaps = 48/268 (17%) Query: 17 ELKKPFSIEEVEVAPPKA--HEVRIKMVAAGICRSDEHVVSGNLVTPL--PVILGHEAAG 72 E P ++ E P+A H++ ++ +A + D+ V+ + L P + + +G Sbjct: 34 ETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSG 93 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 +VE+VG+ VT +PGD+VI F P G L DG R T Sbjct: 94 VVEAVGKSVTRFRPGDRVISTFAP-------------------------GWL-DGLRPGT 127 Query: 133 CSGKPIHHFVGVS---TFSQYTVVDEN----AVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 P + +G + S+Y V+ E A +DAA + + C T + + V Sbjct: 128 GR-TPAYETLGGAHPGVLSEYVVLPEGWFVAAPKSLDAA----EASTLPCAGLTAWFALV 182 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-- 243 + + G V G GGV L + KA G A +I +++K +A LGA IN Sbjct: 183 EKGHLRAGDRVVVQGTGGVALFGLQIAKATG-AEVIVTSSSREKLDRAFALGADHGINRL 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIG 271 +D+ ++ V D G D E+ G Sbjct: 242 EEDW---VERVYALTGDRGADHILEIAG 266 >1YQX-A nrPDB Length = 366 Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 79/308 (25%), Positives = 121/308 (39%), Gaps = 30/308 (9%) Query: 36 EVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +VR K++ G+C SD H + + + P++ GHE G V VG V V GDKV + Sbjct: 43 DVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVGVGC 102 Query: 94 FTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVV 153 C C C N NYC K L DGT + +S + V Sbjct: 103 LVGACHSCESCANDLENYCPKMIL-TYASIYHDGT-------------ITYGGYSNHMVA 148 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 +E + + PL+ + C T Y PG + GLGG+G V K Sbjct: 149 NERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVKFAK 208 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 A G+ + K K GA + +D QE ++ G +D + + + Sbjct: 209 AFGSKVTVISTSPSKKEEALKNFGADSFLVSRD-----QEQMQAAA-GTLDGIIDTVSAV 262 Query: 274 DTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTW-KGAIFGGFKSKESVPKL 332 ++ L ++ G ++VG P + L + L+ GR G+ GG K + Sbjct: 263 HPLLP-LFGLLKSHGKLILVGAP--EKPLELPAFSLIAGRKIVAGSGIGGMKETQE---- 315 Query: 333 VADFMAKK 340 + DF AK Sbjct: 316 MIDFAAKH 323 >1WLY-A nrPDB Length = 333 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 76/285 (26%), Positives = 117/285 (41%), Gaps = 69/285 (24%) Query: 12 AAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL-----PV 64 AAV+ + P F EEV+V P +VR++ A G+ D + +G + PL P+ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAG-IPHPLVVGEPPI 62 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTL 124 ++G EAA +VE VG GVT G++V P Sbjct: 63 VVGFEAAAVVEEVGPGVTDFTVGERVCTCLPP---------------------------- 94 Query: 125 QDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGC---GFSTGY 181 + +SQ + + K+ L+ V L G G + Y Sbjct: 95 -------------------LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQY 135 Query: 182 GSAVKVAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 + KV PG + GG+G +V + GA +I ++K A++LG Sbjct: 136 -LLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGAT-VIGTVSTEEKAETARKLGCHH 193 Query: 241 CIN--PQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLC 282 IN QD+ EV++E+T G GVD ++ IG+ DT+ SL C Sbjct: 194 TINYSTQDFA----EVVREITGGKGVDVVYDSIGK-DTLQKSLDC 233 >2CDC-A nrPDB Length = 366 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 9/108 (8%) Query: 36 EVRIKMVAAGICRSDEHVVSGNL-VTPLP-----VILGHEAAGIVESVGEGVTTVKPGDK 89 +++I+ + GIC +D +V+G L ++ LP ++LGHEA G+VE G + GD Sbjct: 28 KIKIRTIYNGICGADREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYHGFSQ---GDL 84 Query: 90 VIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137 V+P+ CG CR C ++C + G DG R P Sbjct: 85 VMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKMDGFMREWWYDDP 132 >3QWB-A nrPDB Length = 334 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 99/261 (37%), Gaps = 57/261 (21%) Query: 25 EEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 E+ V E+ IK G+ + + G P +LG EA+G V + G+GVT Sbjct: 26 EDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNF 85 Query: 85 KPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGV 144 + GD+V ++ Sbjct: 86 EVGDQV-------------------------------------------------AYISN 96 Query: 145 STFSQYT-VVDENAVAKIDAASPLEKVCLIGCGFS---TGYGSAVKVAKVTPGSTCAVFG 200 STF+QY+ + + V K+ + E++ L G T + V G +F Sbjct: 97 STFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFA 156 Query: 201 L-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 GGVGL + K GA IAV +K AKE GA IN + +++VLK Sbjct: 157 AAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLKFTN 214 Query: 260 DGGVDFSFEVIGRLDTMMASL 280 GVD SF+ +G+ DT SL Sbjct: 215 GKGVDASFDSVGK-DTFEISL 234 >1YB5-A nrPDB Length = 351 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 82/374 (21%), Positives = 150/374 (40%), Gaps = 64/374 (17%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIE---EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN 57 M+T K+++ A ++E P ++ ++ V PK H+V IK+ A G+ + ++ SG Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 LVTP--LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKN 115 LP G + AG++E+VG+ + K GD+V FT Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRV---FTSS------------------ 119 Query: 116 DLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 T SG +++Y + ++ V K+ ++ IG Sbjct: 120 ----------------TISG----------GYAEYALAADHTVYKLPEKLDFKQGAAIGI 153 Query: 176 GFSTGYGSAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAK 234 + T Y + + A V G + V G GGVGL+ +A G +I+ ++ Sbjct: 154 PYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVL 212 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + GA E N ++ I ++ K + + G+D E++ ++ L H G ++VG Sbjct: 213 QNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSH--GGRVIVVG 269 Query: 295 VPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMA--KKFSLDALITNILP 352 + INP + + + +KE + A A + L +I + P Sbjct: 270 ---SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYP 326 Query: 353 FEKINEGFDLLRSG 366 EK+ E + + G Sbjct: 327 LEKVAEAHENIIHG 340 >5H83-A nrPDB Length = 360 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 ++V+ K++ G C D + + +T P ++GHE G+V +G V K GDKV + Sbjct: 40 NDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVGVG 99 Query: 93 LFTPQCGKCRICKNPESNYCLK 114 F C KC +C N N C K Sbjct: 100 GFVGACEKCEMCVNGVENNCSK 121 >1QOR-A nrPDB Length = 327 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%) Query: 21 PFSIEEVEVAP--PKAHEVRIKMVAAGICRSDEHVVSGNLVTP-LPVILGHEAAGIVESV 77 P ++ VE P P +E++++ A GI D ++ SG P LP LG EAAGIV V Sbjct: 13 PEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVSKV 72 Query: 78 GEGVTTVKPGDKVI 91 G GV +K GD+V+ Sbjct: 73 GSGVKHIKAGDRVV 86 >1Q1N-A nrPDB Length = 360 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 44/162 (27%), Positives = 70/162 (43%), Gaps = 23/162 (14%) Query: 31 PPKAHEVRIKMVAAGICRSDEHVVSGNLVT-PLPVILGHEAAGIVESVG-EGVTTVKPGD 88 P H++ IK+ A G+C SD H +G+ +P+++GHE G V +G + + +K G Sbjct: 30 PFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKVGQ 89 Query: 89 KV---IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHH-FVGV 144 +V +F+ C +C CKN YC T+ T +P +V Sbjct: 90 RVGVGAQVFS--CLECDRCKNDNEPYC---------------TKFVTTYSQPYEDGYVSQ 132 Query: 145 STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 ++ Y V E+ V I P + CG T Y V+ Sbjct: 133 GGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVR 174 >3SLK-A nrPDB Length = 795 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/237 (23%), Positives = 87/237 (36%), Gaps = 69/237 (29%) Query: 16 WELK--KPFSI-------EEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVIL 66 W L+ +P S+ E AP EVRI M AAG+ D + G + P L Sbjct: 211 WRLEATRPGSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALG--MYPGVASL 268 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 G E AG+V G GVT + PGD+V+ + P+ Sbjct: 269 GSEGAGVVVETGPGVTGLAPGDRVMGMI-PKA---------------------------- 299 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 F V D V +I A + + F T Y + V Sbjct: 300 --------------------FGPLAVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVD 339 Query: 187 VAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAA--------RIIAVDINKDKFAKAK 234 +A + PG + V GGVG++ + + GA + AV+++++ A ++ Sbjct: 340 LAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDKWQAVELSREHLASSR 396 >3B70-A nrPDB Length = 371 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 78/357 (21%), Positives = 130/357 (36%), Gaps = 72/357 (20%) Query: 36 EVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFT 95 +V +++ A I SD + G TP LG + AG V +VG VT ++ GD+V Sbjct: 38 QVYVRVEAVAINPSDTKM-RGQFATPW-AFLGTDYAGTVVAVGSDVTHIQVGDRV----- 90 Query: 96 PQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDE 155 Y +N++ C P FSQYTV Sbjct: 91 ---------------YGAQNEM---------------CPRTPDQ-----GAFSQYTVTRG 115 Query: 156 NAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV---------AKVTPGSTCAVFGL---GG 203 AKI E+ + G ST G A+K+ A P + V+ L G Sbjct: 116 RVWAKIPKGLSFEQAAALPAGISTA-GLAMKLLGLPLPSPSADQPPTHSKPVYVLVYGGS 174 Query: 204 VGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEMTDGG 262 + V + I + F AK GA E DY+ P + + ++ T Sbjct: 175 TATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVF---DYRAPNLAQTIRTYTKNN 231 Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD--------SQNLSINPMLLLTGRT 314 + ++ + I +++ A G V + P+ + + ++ P + G T Sbjct: 232 LRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTDWTLGPTIFGEGST 291 Query: 315 WKGAIFGGFKSKESVPKLVADF--MAKKFSLDALITNILPFEKINEGFDLLRSGKSI 369 W A +G S+E + D +A + D + + P + GFD ++ G + Sbjct: 292 WP-APYGRPGSEEER-QFGEDLWRIAGQLVEDGRLVH-HPLRVVQGGFDHIKQGMEL 345 >4A27-A nrPDB Length = 349 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Query: 32 PKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTTVKPGDK 89 P+ E++I++ A G+ D V GN+ P P++ G E +GIVE++G+ V + GD+ Sbjct: 28 PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 87 Query: 90 VIPLFTPQCGKCRICKNPESNYCLKNDL 117 V+ +C E Y + +D+ Sbjct: 88 VMAFVNYNAWAEVVCTPVEFVYKIPDDM 115 >3JYN-A nrPDB Length = 325 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 66/246 (26%), Positives = 93/246 (37%), Gaps = 56/246 (22%) Query: 21 PFSIEEVEVAP--PKAHEVRIKMVAAGICRSDEHVVSGNLVTP-LPVILGHEAAGIVESV 77 P +E V+ P P V ++ A G+ D + SG P LP LG E AG+VE+V Sbjct: 13 PEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVEAV 72 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137 G+ VT K GD+V P + PE+N Sbjct: 73 GDEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANL-------------------------- 106 Query: 138 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCA 197 V D+ S + L+ G + Y + +V PG Sbjct: 107 --------------------VKLADSVSFEQAAALMLKGLTVQY-LLRQTYQVKPGEIIL 145 Query: 198 VF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY-KKPIQEVL 255 GGVG KA G A++I + +K A AK LGA E I DY + + + + Sbjct: 146 FHAAAGGVGSLACQWAKALG-AKLIGTVSSPEKAAHAKALGAWETI---DYSHEDVAKRV 201 Query: 256 KEMTDG 261 E+TDG Sbjct: 202 LELTDG 207 >3WID-A nrPDB Length = 369 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 11/101 (10%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPLP-----VILGHEAAGIVESVGE 79 ++++ P+ +E ++K V GIC +D V+G L T P ++LGHEA V V + Sbjct: 20 KIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSD 79 Query: 80 GVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 +K GD V+PL + GKC C+ + C +G+P Sbjct: 80 N-NYIKRGDFVVPLVR-RPGKCVNCRIGRQDNC---SIGDP 115 >3FBG-A nrPDB Length = 346 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 5/71 (7%) Query: 22 FSIEEVEVAPPKAHE--VRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGE 79 F +++ PK HE V+I+ ++ + + ++ V+ P +LG +A G+VESVG Sbjct: 20 FKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD---VSKAPRVLGFDAIGVVESVGN 76 Query: 80 GVTTVKPGDKV 90 VT GD V Sbjct: 77 EVTMFNQGDIV 87 >6C49-A nrPDB Length = 350 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGHEAAGIVESVGE 79 P+ + E+ P H+V +K+ G+C SD V++ T PV+ GHE G + ++G Sbjct: 28 PYKFDAGELQP---HQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIVALGS 84 Query: 80 GVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDL 117 ++ G +V I C C C + C ++ Sbjct: 85 EAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENI 123 >4RVS-A nrPDB Length = 329 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 5/82 (6%) Query: 32 PKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGV----TTVKPG 87 P E+ IK A G+ D + SG LP ++G E G VE+VG GV T + G Sbjct: 26 PGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVG 85 Query: 88 DKVIPLFTPQCGKCRICKNPES 109 D+V+ + C P S Sbjct: 86 DRVVSA-SANGAYAEFCTAPAS 106 >2WEK-A nrPDB Length = 341 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 6/132 (4%) Query: 141 FVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFG 200 ++ +F++YTVV + + + P E + L+ G +T Y S ++ ++ G V Sbjct: 93 YMAPGSFAEYTVVPASIATPVPSVKP-EYLTLLVSG-TTAYISLKELGGLSEGKKVLVTA 150 Query: 201 LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KPIQEVLKEMT 259 G M +I + +K A K LG C P +YK +P+ VLK+ Sbjct: 151 AAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLG---CDRPINYKTEPVGTVLKQEY 207 Query: 260 DGGVDFSFEVIG 271 GVD +E +G Sbjct: 208 PEGVDVVYESVG 219 >4IDE-A nrPDB Length = 332 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 3/61 (4%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSG---NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDK 89 K +V IK+VAA + D G + +PLP I G++ AG+V VG VT K GD+ Sbjct: 51 KEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTKFKVGDE 110 Query: 90 V 90 V Sbjct: 111 V 111 >4Y1B-A nrPDB Length = 425 Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust. Identities = 67/279 (24%), Positives = 115/279 (41%), Gaps = 55/279 (19%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVIL--------------G 67 F E V+V P +V +K++AAG+ ++ V L PL VI G Sbjct: 58 FRTEVVDVPPVGPGQVLVKVMAAGVNYNN---VWAALGEPLDVIAARQKQGATEDFHIGG 114 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 + +GIV +VG+GV +KPG +V+ L CR ++ + ++ G Sbjct: 115 SDLSGIVWAVGDGV-RLKPGAEVVVL------ACRWDESAQD--------------IRLG 153 Query: 128 TRRFTCSGKPIHHF-VGVSTFSQYTVVDENAVA-KIDAASPLEKVCLIGCGFSTGYGS-- 183 T S + + + +F+Q+ VVDE K S C + +T Y Sbjct: 154 ADPVTSSTQRVWGYEENYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATA-ATAYRQLF 212 Query: 184 AVKVAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 + V PG ++ G GG+G + + G +AV ++++ LGA I Sbjct: 213 GWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGI-PVAVVSSEERGEFCMRLGAKGWI 271 Query: 243 NPQDYKK-------PIQEVLKEMTDGGVDFS---FEVIG 271 + +++ +E +K+ DG F +EV+G Sbjct: 272 DRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLG 310 >3HZZ-A nrPDB Length = 467 Score = 36.2 bits (82), Expect = 0.021, Method: Compositional matrix adjust. Identities = 69/313 (22%), Positives = 119/313 (38%), Gaps = 66/313 (21%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTL 124 I+G + AG+V G GV +PGD+V+ +CL +L +P G Sbjct: 138 IIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELESPDG-- 177 Query: 125 QDGTRRFTCSGKPIHHFVGVST----FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 D T P G T ++ +V N + E+ G ST Sbjct: 178 HDDTML-----DPEQRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTA 232 Query: 181 YGSAVKV--AKVTPGSTCAVFGL-GGVG-----LSVVMG---------------CKAAGA 217 Y V A + G ++G GG+G ++ G C++ GA Sbjct: 233 YRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSPQKAEICRSMGA 292 Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM 276 II + KF K + +P+++K+ + ++E+T G +D FE GR +T Sbjct: 293 EAIIDRNAEGYKFWKDE-----HTQDPKEWKR-FGKRIRELTGGEDIDIVFEHPGR-ETF 345 Query: 277 MASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVAD- 335 AS+ + GT + N L ++ + G+ F ++ +L+A Sbjct: 346 GASVYVTRKG-GTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIAKG 404 Query: 336 ----FMAKKFSLD 344 ++K +SL+ Sbjct: 405 KIHPTLSKTYSLE 417 >5A3V-A nrPDB Length = 329 Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 6/75 (8%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL-----PVILGHEAAGIVESVGEG 80 +V V PK++EV +K+ A + D + G ++ P P I + AG V VG G Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKG-MIRPFLPRKFPCIPATDVAGEVVEVGSG 83 Query: 81 VTTVKPGDKVIPLFT 95 V K GDKV+ + + Sbjct: 84 VKNFKAGDKVVAVLS 98 >4DVJ-A nrPDB Length = 363 Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust. Identities = 14/27 (51%), Positives = 21/27 (77%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVI 91 ++G++AAGIV +VG VT +PGD+V Sbjct: 84 VIGYDAAGIVSAVGPDVTLFRPGDEVF 110 >4J6F-A nrPDB Length = 382 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 54/221 (24%), Positives = 85/221 (38%), Gaps = 48/221 (21%) Query: 18 LKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP---------------- 61 L+K +V V P A EV IK+ A G+ +D V G T Sbjct: 45 LEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTL 104 Query: 62 -LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 P I G + G + +VGEGV + G++V+ F+ I + + + +G+ Sbjct: 105 TFPRIQGTDTVGHIVAVGEGVDRARIGERVMVDFS-------IYNRDDDSLADIDYMGHG 157 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 R DG G + + + + VA L C C + TG Sbjct: 158 R----DG---------------GYAEYMALPAENAHVVATDLTDIELATFC---CAYLTG 195 Query: 181 YGSAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARI 220 ++ A++ G T V G GGVG +++ +A GA I Sbjct: 196 E-RMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPI 235 >2OBY-A nrPDB Length = 338 Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 7/127 (5%) Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-GLGGVGL 206 +QY V E + I L + I + T + V V G + GL GVG Sbjct: 102 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 161 Query: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264 + + + AGA ++ K K A++LGA N YKK + LK GV+ Sbjct: 162 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 217 Query: 265 FSFEVIG 271 + IG Sbjct: 218 LILDCIG 224 >4MMI-A nrPDB Length = 643 Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 GL V +V G A ++A K +KA+E + P D ++PI +V +EM Sbjct: 19 GLEKVNKAVAAGNYDDAAKALLAYYREK---SKAREPDFSNAEKPADIRQPIDKVTREMA 75 Query: 260 DGGVDFSFE 268 D + F+ Sbjct: 76 DKALVHQFQ 84 >3TQH-A nrPDB Length = 321 Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust. Identities = 68/301 (22%), Positives = 111/301 (36%), Gaps = 74/301 (24%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPP--KAHEVRIKMVAAGI------CRSDEHVVSGNLVT 60 + KA + P ++ V+ P + +++ IK+ AA + R+ V+ L Sbjct: 6 EMKAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKN 65 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF----TPQCGKCRICKNPESNYCLKND 116 LP LG++ +G V +G V V GDKV+ + P C +C +P++ Sbjct: 66 NLPSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPCCYAEYVCASPDT------- 118 Query: 117 LGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCG 176 + K++ S L+ L G Sbjct: 119 ----------------------------------------IIQKLEKLSFLQAASLPTAG 138 Query: 177 FSTGYGSAVKVAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 + A+ A+V G + G GGVG + K G I F KA Sbjct: 139 LTAL--QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKGTTVITTASKRNHAFLKA-- 194 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGA +CIN + ++ L ++ VD +++G D + S+ C E T IV V Sbjct: 195 LGAEQCINYHE-----EDFLLAIST-PVDAVIDLVGG-DVGIQSIDCLKE---TGCIVSV 244 Query: 296 P 296 P Sbjct: 245 P 245 >6ACF-A nrPDB Length = 367 Score = 31.2 bits (69), Expect = 0.71, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 G AV G+G V + GA ++I DINK+ A+A E + ++P D Sbjct: 173 GKVVAVQGVGNVAYHLCRHLHEEGA-KLIVTDINKEAVARAVEEFGAKAVDPND 225 >2CF5-A nrPDB Length = 357 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 81/346 (23%), Positives = 139/346 (40%), Gaps = 33/346 (9%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILGHEAAGIVESVGE 79 P++ E P +V I+++ GIC +D H +L ++ P++ GHE G V VG Sbjct: 24 PYTYTLRETGP---EDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEVVEVGS 80 Query: 80 GVTTVKPGD-KVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPI 138 V+ GD + CG C C+ YC K +G+P Sbjct: 81 DVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIW---------SYNDVYINGQPT 131 Query: 139 HHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAV 198 F++ TVV + V KI +E+ + C T Y PG + Sbjct: 132 Q-----GGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGI 186 Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 GLGGVG V KA G + NK + ++LGA + + D K + E+ Sbjct: 187 LGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAK-----MSEL 241 Query: 259 TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGA 318 D +D+ + + + + L + G +++GV + + P+L+L + G+ Sbjct: 242 AD-SLDYVIDTVP-VHHALEPYLSLLKLDGKLILMGVINNPLQF-LTPLLMLGRKVITGS 298 Query: 319 IFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364 G K E + + K+ L ++I ++ + +N F+ L Sbjct: 299 FIGSMKETEEMLEF-----CKEKGLSSII-EVVKMDYVNTAFERLE 338 >3SMA-A nrPDB Length = 286 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 24/53 (45%), Gaps = 7/53 (13%) Query: 134 SGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLE-------KVCLIGCGFST 179 SG P + F ++ V + ++ SPLE +V L+GCGF + Sbjct: 136 SGHPQNSFAAWGAHAEQVVAEHGLTERLGRGSPLEQVYRLDGQVLLLGCGFES 188 >4KPA-A nrPDB Length = 494 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 22/42 (52%) Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 KP+Q ++K + G F FE GR+ ++S EAC S Sbjct: 48 KPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDES 89 >5ILO-A nrPDB Length = 271 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 12/82 (14%) Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDI--NKDKFAKAKELGATECI--------NPQDYKK 249 G GG+GL V AAGAA++ +D+ N ++F K + T+ + N + + Sbjct: 23 GAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEA 82 Query: 250 PIQEVLKEMTDGGVDFSFEVIG 271 +E+ K T G +D V G Sbjct: 83 TYEEIAK--TFGNIDIVVNVAG 102 >1TWI-A nrPDB Length = 434 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 23/47 (48%) Query: 175 CGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARII 221 C S +G ++ KV G A+F +G G+S+ A G R++ Sbjct: 358 CESSDVFGRDRELDKVEVGDVLAIFDVGAYGISMANNYNARGRPRMV 404 >6BKV-A nrPDB Length = 114 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 21/83 (25%) Query: 82 TTVKPGDKVIPLFTPQCGKC------------------RICKNPESNYCLKNDLGNPRGT 123 +T+K G ++ + P CG C +ICK N + +L G Sbjct: 22 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYQGKAKICK---VNTDEQEELSAKFGI 78 Query: 124 LQDGTRRFTCSGKPIHHFVGVST 146 T FT G+ +H VGV T Sbjct: 79 RSIPTLLFTKDGEVVHQLVGVQT 101 >1V9L-A nrPDB Length = 421 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 7/63 (11%) Query: 177 FSTGYGSAVKVAKVT-------PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK 229 ++TG+G AV ++ G T A+ G+G VG + GA I DIN Sbjct: 187 YATGFGVAVATREMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVA 246 Query: 230 FAK 232 + K Sbjct: 247 YRK 249 >1VJO-A nrPDB Length = 393 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 20/90 (22%), Positives = 41/90 (45%), Gaps = 3/90 (3%) Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304 Q ++K ++ + + + D G+ E RL T+ + +C + + + N+ + Sbjct: 298 QRHQKNVEYLWERLEDIGLSLHVEKEYRLPTL--TTVCIPDGVDGKAVARRLLNEHNIEV 355 Query: 305 NPML-LLTGRTWKGAIFGGFKSKESVPKLV 333 L L G+ W+ + G KESV +L+ Sbjct: 356 GGGLGELAGKVWRVGLMGFNSRKESVDQLI 385 >4AJW-A nrPDB Length = 934 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 21/37 (56%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDE 51 LW L++PFSIE +E A E +V AG+ +E Sbjct: 207 LWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNE 243 >2VN8-A nrPDB Length = 375 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 88/369 (23%), Positives = 132/369 (35%), Gaps = 88/369 (23%) Query: 35 HEVRIKMVAAGICRSDEHVVSGNLVTPL----------------PVILGHEAAGIVESVG 78 +EV +K+ AA + D ++ SG T L P+ LG + +G+V G Sbjct: 51 NEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECG 110 Query: 79 EGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPI 138 V KPGD+V P +GTL + SG + Sbjct: 111 LDVKYFKPGDEVWAAVPPW----------------------KQGTLSEFV---VVSGNEV 145 Query: 139 HHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA----KVTPGS 194 H T +Q A+ L V L T + + KV K G Sbjct: 146 SHKPKSLTHTQ--------------AASLPYVAL------TAWSAINKVGGLNDKNCTGK 185 Query: 195 TCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK-PIQ 252 + G GGVG + KA A + AV ++D ++LGA + I DYK ++ Sbjct: 186 RVLILGASGGVGTFAIQVMKAWD-AHVTAV-CSQDASELVRKLGADDVI---DYKSGSVE 240 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP--PDSQNLSINPMLLL 310 E LK + DF + +G A + T V + P + L I +L Sbjct: 241 EQLKSLKP--FDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQ 298 Query: 311 TGRT---------WKGAIFGGFKSKESVPKL--VADFMAKKFSLDALITNILPFEKINEG 359 TG T WKG + S P L +A+ + + +I PF K+ E Sbjct: 299 TGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAE-LVDAGKIRPVIEQTFPFSKVPEA 357 Query: 360 FDLLRSGKS 368 F + G + Sbjct: 358 FLKVERGHA 366 >2B25-A nrPDB Length = 336 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 24/51 (47%) Query: 185 VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 + + + PG T G G G+S+ + R+I+ ++ KD AK+ Sbjct: 98 LSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK 148 >1V3V-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 19/118 (16%) Query: 173 IGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV------MGCKAAGAARIIAVDIN 226 IG T Y ++V V G T V G SVV GCK GAA + Sbjct: 126 IGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIAKLKGCKVVGAAG------S 179 Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG--RLDTMMASL 280 +K A K++G N YK ++E LK+ + G D F+ +G L+T+++ + Sbjct: 180 DEKIAYLKQIGFDAAFN---YKTVNSLEEALKKASPDGYDCYFDNVGGEFLNTVLSQM 234 >2VWH-A nrPDB Length = 357 Score = 28.5 bits (62), Expect = 5.0, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 8/66 (12%) Query: 32 PKAHEVRIKMVAAGICRSDEHVVSGNLVTPLP-----VILGHEAAGIVESVGEGVTTVKP 86 P++ E ++ + G+ +D V++G P ++LGHEA G+V V T ++ Sbjct: 23 PESGEALVRTLRVGVDGTDHEVIAGGH-GGFPEGEDHLVLGHEAVGVV--VDPNDTELEE 79 Query: 87 GDKVIP 92 GD V+P Sbjct: 80 GDIVVP 85 >1JGT-A nrPDB Length = 513 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 49/128 (38%), Gaps = 20/128 (15%) Query: 134 SGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 193 SG + H S+ + + AVA + AA LEK +VTPG Sbjct: 199 SGTAVTHRTWTPGLSRRILPEGEAVAAVRAA--LEKAV---------------AQRVTPG 241 Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKD---KFAKAKELGATECINPQDYKKP 250 T V GG+ S V C A + V + D +F +A+ + ++ P Sbjct: 242 DTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIP 301 Query: 251 IQEVLKEM 258 E+L ++ Sbjct: 302 TTELLAQL 309 >4A10-A nrPDB Length = 447 Score = 27.7 bits (60), Expect = 9.1, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 17/27 (62%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVI 91 +LG + +G+V G GV KPGD VI Sbjct: 112 VLGSDCSGVVVRTGIGVRRWKPGDHVI 138 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1U3W-A nrPDB 501 e-142 1HSZ-A nrPDB 500 e-142 1HSO-A nrPDB 496 e-141 1EE2-A nrPDB 470 e-133 1D1T-A nrPDB 437 e-123 3COS-A nrPDB 437 e-123 1MC5-A nrPDB 429 e-120 4DLA-A nrPDB 426 e-120 4JJI-A nrPDB 421 e-118 1CDO-A nrPDB 420 e-118 4RQU-A nrPDB 412 e-115 1E3E-A nrPDB 410 e-115 1P0F-A nrPDB 398 e-111 3PII-A nrPDB 309 1e-84 5TNX-A nrPDB 298 3e-81 1F8F-A nrPDB 297 4e-81 3MEQ-A nrPDB 296 1e-80 4Z6K-A nrPDB 290 9e-79 1LLU-A nrPDB 288 4e-78 2DFV-A nrPDB 284 3e-77 3S2F-A nrPDB 284 4e-77 3GFB-A nrPDB 276 1e-74 2EER-A nrPDB 271 2e-73 6N7L-A nrPDB 268 2e-72 1PL8-A nrPDB 267 4e-72 3QE3-A nrPDB 265 2e-71 2DQ4-A nrPDB 263 7e-71 5KIA-A nrPDB 261 3e-70 4CPD-A nrPDB 258 2e-69 4EEZ-A nrPDB 257 6e-69 1H2B-A nrPDB 256 1e-68 1R37-A nrPDB 250 6e-67 5YLN-A nrPDB 244 3e-65 5ENV-A nrPDB 244 5e-65 5VM2-A nrPDB 242 2e-64 1UUF-A nrPDB 239 1e-63 5H82-A nrPDB 237 5e-63 4EJ6-A nrPDB 236 1e-62 1E3J-A nrPDB 236 1e-62 1YKF-A nrPDB 232 2e-61 4GKV-A nrPDB 229 1e-60 5YAT-A nrPDB 229 1e-60 3FPL-A nrPDB 228 2e-60 4OH1-A nrPDB 228 4e-60 5K1S-A nrPDB 226 1e-59 1YQX-A nrPDB 224 6e-59 5Z0C-A nrPDB 223 1e-58 3FSR-A nrPDB 223 1e-58 3FPC-A nrPDB 222 2e-58 3TWO-A nrPDB 222 2e-58 4OAQ-A nrPDB 219 1e-57 1KEV-A nrPDB 219 2e-57 2H6E-A nrPDB 218 4e-57 6DKH-A nrPDB 213 1e-55 5FI5-A nrPDB 209 2e-54 4ILK-A nrPDB 208 3e-54 6FG0-A nrPDB 208 5e-54 3M6I-A nrPDB 207 8e-54 4UEJ-A nrPDB 206 1e-53 3IP1-A nrPDB 206 2e-53 2OUI-A nrPDB 202 2e-52 5VKT-A nrPDB 200 1e-51 5H83-A nrPDB 199 2e-51 1YB5-A nrPDB 195 3e-50 3UOG-A nrPDB 191 4e-49 2DPH-A nrPDB 182 1e-46 3WLE-A nrPDB 182 2e-46 4JLW-A nrPDB 182 2e-46 1Q1N-A nrPDB 180 9e-46 1KOL-A nrPDB 172 2e-43 3QWB-A nrPDB 172 2e-43 1WLY-A nrPDB 160 8e-40 3B70-A nrPDB 154 8e-38 2VCY-A nrPDB 153 1e-37 1QOR-A nrPDB 152 3e-37 3JYN-A nrPDB 140 9e-34 4A27-A nrPDB 127 9e-30 3SLK-A nrPDB 125 4e-29 2CDC-A nrPDB 112 4e-25 3WID-A nrPDB 102 4e-22 Sequences not found previously or not previously below threshold: 6C49-A nrPDB 168 3e-42 2CF5-A nrPDB 152 2e-37 4RVS-A nrPDB 145 2e-35 2OBY-A nrPDB 130 1e-30 4J6F-A nrPDB 129 1e-30 3HZZ-A nrPDB 127 1e-29 3FBG-A nrPDB 120 9e-28 3TQH-A nrPDB 120 1e-27 4A10-A nrPDB 119 2e-27 4Y1B-A nrPDB 116 2e-26 4IDE-A nrPDB 111 5e-25 2VN8-A nrPDB 110 7e-25 2WEK-A nrPDB 108 4e-24 4EYE-A nrPDB 107 1e-23 5A3V-A nrPDB 107 1e-23 4DVJ-A nrPDB 104 6e-23 2VWH-A nrPDB 100 1e-21 5LB9-A nrPDB 81 7e-16 1V3V-A nrPDB 79 5e-15 2Y05-A nrPDB 74 1e-13 5GXF-A nrPDB 71 6e-13 1O89-A nrPDB 65 4e-11 2J3K-A nrPDB 62 6e-10 2VNA-A nrPDB 57 1e-08 2ZB3-A nrPDB 53 3e-07 1ZCJ-A nrPDB 43 3e-04 3ZWA-A nrPDB 42 5e-04 2EGU-A nrPDB 41 0.001 4DIO-A nrPDB 40 0.001 3MGG-A nrPDB 40 0.002 5ILO-A nrPDB 40 0.002 5JE5-A nrPDB 39 0.005 2VHY-A nrPDB 38 0.006 3X2F-A nrPDB 38 0.008 6BII-A nrPDB 37 0.010 1X14-A nrPDB 37 0.010 2B25-A nrPDB 37 0.011 1BW9-B nrPDB 37 0.016 1XLT-A nrPDB 37 0.016 5EKU-A nrPDB 36 0.022 4M36-A nrPDB 36 0.022 1VH3-A nrPDB 36 0.023 4INE-A nrPDB 36 0.023 3VPX-A nrPDB 36 0.030 6BQC-A nrPDB 36 0.031 6ACF-A nrPDB 35 0.044 5Z1Z-A nrPDB 35 0.044 1V8B-A nrPDB 35 0.050 4XIJ-A nrPDB 35 0.054 4K2X-A nrPDB 35 0.061 1V9L-A nrPDB 34 0.082 4N7R-A nrPDB 34 0.085 5JJC-A nrPDB 34 0.087 5F8E-A nrPDB 34 0.11 1DXY-A nrPDB 34 0.12 2O23-A nrPDB 34 0.14 1EUF-A nrPDB 34 0.14 1W1U-A nrPDB 34 0.14 5JXW-A nrPDB 34 0.14 2YVG-A nrPDB 34 0.15 3D2L-A nrPDB 34 0.16 3KYD-B nrPDB 34 0.17 3KYC-B nrPDB 34 0.17 5AOV-A nrPDB 33 0.19 4CUK-A nrPDB 33 0.19 1JWB-B nrPDB 33 0.22 6C55-A nrPDB 33 0.22 5D84-A nrPDB 33 0.23 3EGI-A nrPDB 33 0.24 3GDH-A nrPDB 33 0.24 2EEZ-A nrPDB 33 0.25 4COO-A nrPDB 33 0.27 1E3W-A nrPDB 33 0.29 1M54-A nrPDB 32 0.31 4FS8-A nrPDB 32 0.32 5VMT-A nrPDB 32 0.32 5MMS-A nrPDB 32 0.32 1ZFN-A nrPDB 32 0.32 4XGI-A nrPDB 32 0.34 2BHS-A nrPDB 32 0.41 1CYD-A nrPDB 32 0.41 5UYY-A nrPDB 32 0.42 3G1U-A nrPDB 32 0.42 3X43-A nrPDB 32 0.43 3AOE-A nrPDB 32 0.51 4K28-A nrPDB 32 0.54 2EKL-A nrPDB 32 0.56 3FBT-A nrPDB 32 0.58 1XDW-A nrPDB 32 0.62 3D3W-A nrPDB 32 0.62 1GPJ-A nrPDB 31 0.66 3BKX-A nrPDB 31 0.76 4YRY-B nrPDB 31 0.78 3JTJ-A nrPDB 31 0.80 1I9G-A nrPDB 31 0.80 3OAM-A nrPDB 31 0.83 4KIC-A nrPDB 31 0.83 6IQV-A nrPDB 31 0.85 1VE9-A nrPDB 31 0.85 5U9P-A nrPDB 31 0.87 3CJR-A nrPDB 31 0.89 4OM8-A nrPDB 31 0.96 5OHX-A nrPDB 31 1.00 6J0Z-C nrPDB 31 1.0 2X36-A nrPDB 30 1.1 1EUA-A nrPDB 30 1.2 6GME-A nrPDB 30 1.2 2HMT-A nrPDB 30 1.2 3EMK-A nrPDB 30 1.2 2ZJ1-A nrPDB 30 1.2 5BUT-A nrPDB 30 1.3 4PZE-A nrPDB 30 1.3 1HL3-A nrPDB 30 1.3 3TNL-A nrPDB 30 1.3 2ISQ-A nrPDB 30 1.3 2BRY-A nrPDB 30 1.4 4TXK-A nrPDB 30 1.4 6GBN-A nrPDB 30 1.4 6APH-A nrPDB 30 1.5 2JC3-A nrPDB 30 1.5 6FZI-A nrPDB 30 1.5 4DIM-A nrPDB 30 1.6 4FHN-X nrPDB 30 1.6 3NJ4-A nrPDB 30 1.7 1QO8-A nrPDB 30 1.7 5ZBK-A nrPDB 30 1.7 3DC2-A nrPDB 30 1.7 1WG8-A nrPDB 30 1.7 4MOP-A nrPDB 30 1.8 4J90-A nrPDB 30 1.9 2WWR-A nrPDB 30 1.9 2RIR-A nrPDB 30 1.9 2NVU-B nrPDB 30 2.0 1YOV-B nrPDB 30 2.0 1LTH-T nrPDB 30 2.1 1FI8-A nrPDB 30 2.1 2AS0-A nrPDB 30 2.1 4KUG-A nrPDB 30 2.1 3ZZN-A nrPDB 30 2.2 3F9I-A nrPDB 30 2.2 5UJU-A nrPDB 30 2.2 3HDH-A nrPDB 30 2.3 3OND-A nrPDB 30 2.4 6DLL-A nrPDB 30 2.5 5FUB-A nrPDB 29 2.8 4DIB-A nrPDB 29 2.8 1F14-A nrPDB 29 2.8 2YFH-A nrPDB 29 2.9 6HNS-A nrPDB 29 3.0 3WGE-A nrPDB 29 3.1 5M0P-A nrPDB 29 3.1 5TQV-A nrPDB 29 3.2 4F86-A nrPDB 29 3.2 2QHR-L nrPDB 29 3.3 5XW3-A nrPDB 29 3.4 2DR1-A nrPDB 29 3.5 2YU3-A nrPDB 29 3.7 2DK5-A nrPDB 29 3.7 5NMX-A nrPDB 29 3.7 4GCM-A nrPDB 29 3.7 3FEO-A nrPDB 29 3.7 6ABI-A nrPDB 29 3.8 2E28-A nrPDB 29 4.0 3H9U-A nrPDB 29 4.1 3GRP-A nrPDB 29 4.1 1KZH-A nrPDB 29 4.1 1YPF-A nrPDB 29 4.2 3PPI-A nrPDB 29 4.3 3H5A-A nrPDB 28 4.4 1DOD-A nrPDB 28 4.4 3JTM-A nrPDB 28 4.5 4D3F-A nrPDB 28 4.7 4P4L-A nrPDB 28 5.0 3GDF-A nrPDB 28 5.1 4WJI-A nrPDB 28 5.1 4IZO-A nrPDB 28 5.2 3NNK-A nrPDB 28 5.3 3IC9-A nrPDB 28 5.3 3HM2-A nrPDB 28 5.3 3AOE-E nrPDB 28 5.4 3TQD-A nrPDB 28 5.4 1B26-A nrPDB 28 5.5 5MH6-A nrPDB 28 5.9 1LSS-A nrPDB 28 6.0 3OC4-A nrPDB 28 6.1 3HWR-A nrPDB 28 6.2 2YQ5-A nrPDB 28 6.2 1L1F-A nrPDB 28 6.4 4ZV2-A nrPDB 28 6.6 6DHM-A nrPDB 28 6.6 4RDI-A nrPDB 28 6.6 5IJZ-A nrPDB 28 6.9 2LDB-A nrPDB 28 6.9 3T5Y-A nrPDB 28 7.0 1ZEJ-A nrPDB 28 7.3 1V9C-A nrPDB 28 7.5 4PRK-A nrPDB 28 7.7 5B37-A nrPDB 28 7.9 3GG9-A nrPDB 28 8.1 2GMH-A nrPDB 28 8.2 5EES-A nrPDB 28 8.3 3OJO-A nrPDB 28 9.3 4MIE-A nrPDB 28 9.4 2YY8-A nrPDB 28 9.4 4L4S-H nrPDB 27 9.6 4GBJ-A nrPDB 27 9.6 1BG6-A nrPDB 27 9.7 5JFC-L nrPDB 27 9.9 >1U3W-A nrPDB Length = 374 Score = 501 bits (1289), Expect = e-142, Method: Composition-based stats. Identities = 372/374 (99%), Positives = 374/374 (100%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIG+LDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITN+LPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFD 360 Query: 362 LLRSGKSIRTVLTF 375 LLRSGKSIRTVLTF Sbjct: 361 LLRSGKSIRTVLTF 374 >1HSZ-A nrPDB Length = 374 Score = 500 bits (1287), Expect = e-142, Method: Composition-based stats. Identities = 354/374 (94%), Positives = 366/374 (97%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVA GICR+D+HVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR+CKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTC GKPIHHF+G STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS VMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 300 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LSINPMLLLTGRTWKGA++GGFKSKE +PKLVADFMAKKFSLDALIT++LPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLRSGKSIRTVLTF 375 LL SGKSIRTVLTF Sbjct: 361 LLHSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 496 bits (1278), Expect = e-141, Method: Composition-based stats. Identities = 347/374 (92%), Positives = 359/374 (95%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVA GIC +D+HVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCRICKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 120 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTC KPIHHF+G+STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS +MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LS+NPMLLLTGRTWKGAI GGFKSKE VPKLVADFMAKKFSLDALIT++LPFEKINEGFD Sbjct: 301 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLRSGKSIRTVLTF 375 LL SGKSIRT+L F Sbjct: 361 LLHSGKSIRTILMF 374 >1EE2-A nrPDB Length = 373 Score = 470 bits (1209), Expect = e-133, Method: Composition-based stats. Identities = 327/374 (87%), Positives = 351/374 (93%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 STAGKVIKCKAAVLWE KKPFSIEEVEVAPPKAHEVRIKMVAAGICRSD+HVVSG LV P Sbjct: 1 STAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPVI GHEAAGIVES+GEGVTTV+PGDKVIPLF PQCGKC +CK+PE N CLK +L PR Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLK-NLSMPR 119 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GT+QDGT RFTC GKPIHHF+G STFSQYTVVDE +VAKIDAASPLEKVCL+GCGFSTGY Sbjct: 120 GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY 179 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVKVAKVT GSTCAVFGLGGVGLSV+MGCKAAGAARII VDINKDKFAKAKE+GATEC Sbjct: 180 GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 +NPQDYKKPIQEVL EM++GGVDFSFEVIGRLDTM+A+L CC EA G SVIVGVPPDSQN Sbjct: 240 VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN 299 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 LS+NPMLLL+GRTWKGAIFGGFKSK+SVPKLVADFMAKKF+LD LIT++LPFEKINEGFD Sbjct: 300 LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD 359 Query: 362 LLRSGKSIRTVLTF 375 LLRSGKSIRT+LTF Sbjct: 360 LLRSGKSIRTILTF 373 >1D1T-A nrPDB Length = 373 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 258/374 (68%), Positives = 313/374 (83%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GICR+D+HV+ G +V+ Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ R Sbjct: 61 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDI-TGR 119 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 G L DGT RFTC GKP+HHF+ STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGY Sbjct: 120 GVLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGY 179 Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G+AVK KV PGSTC VFGLGGVGLSV+MGCK+AGA+RII +D+NKDKF KA +GATEC Sbjct: 180 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 I+P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ Sbjct: 240 ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKM 299 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 L+ +PMLL TGRTWKG +FGG KS++ VPKLV +F+AKKF LD LIT++LPF+KI+EGF+ Sbjct: 300 LTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 359 Query: 362 LLRSGKSIRTVLTF 375 LL SG+SIRTVLTF Sbjct: 360 LLNSGQSIRTVLTF 373 >3COS-A nrPDB Length = 381 Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats. Identities = 225/380 (59%), Positives = 280/380 (73%), Gaps = 5/380 (1%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-V 59 M T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C +D V+ Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 60 TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKND--- 116 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 117 -LGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 + + ++D T RFTC GKP++HF G STFSQYTVV + +AKID + LE+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 176 GFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 GFSTGYG+A+ AKVTPGSTCAVFGLGGVGLS VMGCKAAGA+RII +DIN +KF KAK Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 296 PPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEK 355 S+ L++ P L+ GRT G FGG+KS +S+PKLV D+ KKF+LDAL+T+ LPF+K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 356 INEGFDLLRSGKSIRTVLTF 375 I+E FDL+ GKSIRT+L F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1MC5-A nrPDB Length = 374 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 234/371 (63%), Positives = 289/371 (77%), Gaps = 1/371 (0%) Query: 4 AGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP-L 62 A +VIKCKAAV WE KP SIEE+EVAPPKAHEVRIK++A +C +D + +SG Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG 122 PVILGHE AGIVESVGEGVT +K GD VIPL+ PQCG+C+ C NP++N C K + +G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 123 TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + DGT RFTC GK I H++G STFS+YTVV + +VAKID +PL+KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AV AK+ PGS CAVFGLGGVGL+V+MGCK AGA+RII VDINKDKFA+AKE GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 NPQD+ KPIQEVL EMTDGGVD+SFE IG + M A+L CH+ G SV+VGV + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 303 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDL 362 + P L+TGRTWKG FGG+KS ESVPKLV+++M+KK +D +T+ L F++IN+ F+L Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 363 LRSGKSIRTVL 373 + SGKSIRTV+ Sbjct: 362 MHSGKSIRTVV 372 >4DLA-A nrPDB Length = 396 Score = 426 bits (1095), Expect = e-120, Method: Composition-based stats. Identities = 198/376 (52%), Positives = 259/376 (68%), Gaps = 2/376 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 +T G+VI CKAAV WE KP IE+V+VAPP+A EVR+K++ +C +D + SG Sbjct: 19 ATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEG 78 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 L P +LGHEAAGIVESVGEGVT V+PGD VIP + +C +C+ CK+ ++N C K Sbjct: 79 LFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATG 138 Query: 121 RG-TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ +GKPI+HF+G STFSQYTVV + +VAKID +PLEKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ AKV PGS AVFGLG VGL+V G KAAGA+RII +DI+ KF +AK G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E INP+++++PIQ+V+ ++TDGGVD+SFE IG + M ++L CCH+ GTSVIVGV Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 Q +S P L+TGR WKG FGGFKS+ VP LV ++ K+ +D IT+ + IN+ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 360 FDLLRSGKSIRTVLTF 375 FDL+ G +R VL Sbjct: 379 FDLMHDGDCLRVVLDM 394 >4JJI-A nrPDB Length = 378 Score = 421 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 199/375 (53%), Positives = 256/375 (68%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 +T G+VI CKAAV +E KP IE+V+VAPP+A EVRIK++ +C +D + SG Sbjct: 1 ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 60 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 L P ILGHEAAGIVESVGEGVT V+ GD VIP + +C +C+ CK+ ++N C K Sbjct: 61 LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 120 Query: 121 RG-TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ +GKPI+HF+G STFSQYTVV + +VAKID +PL+KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ AKV PGS A+FGLG VGL+V G K AGA+RII +DI+ K+ AK+ G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E +NP+D+ KPIQEV+ ++TDGGVD+SFE IG + M A+L CCH+ GTSVIVGV Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 Q +S P L+TGR WKG FGGFKS+ VP LV +M K+ +D IT+ L +IN+ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 360 FDLLRSGKSIRTVLT 374 FDLL G +R VL Sbjct: 361 FDLLHEGTCLRCVLD 375 >1CDO-A nrPDB Length = 374 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 205/375 (54%), Positives = 268/375 (71%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDE-HVVSGNLVT 60 +T GKVIKCKAAV WE KP IEE+EV P A+E+RIK++A G+C +D H+ G Sbjct: 1 ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 PV+LGHE AGIVESVG GVT +PG+KVIPLF QCG+CR C++P++N C+K Sbjct: 61 GFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANES 120 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 + RFTC G+ + F+G STFSQYTVV++ AVAKID ++PL+ VCL+GCG STG Sbjct: 121 PDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTG 180 Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +G+AV AKV PGSTCAVFGLG VGL+ VMGC +AGA RIIAVD+N DKF KAK GAT+ Sbjct: 181 FGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATD 240 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 +NP D+ +PI +VL +MT+GGVDFS E +G + M +L C + G SV+VG D Sbjct: 241 FVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGW-TDLH 299 Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360 +++ P+ L+ GRTWKG++FGGFK K+ VPK+V ++ KK LD IT+ +P E +N+ Sbjct: 300 DVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAI 359 Query: 361 DLLRSGKSIRTVLTF 375 DL++ GK IRTVL+ Sbjct: 360 DLMKHGKCIRTVLSL 374 >4RQU-A nrPDB Length = 375 Score = 412 bits (1059), Expect = e-115, Method: Composition-based stats. Identities = 186/372 (50%), Positives = 248/372 (66%), Gaps = 2/372 (0%) Query: 6 KVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL-PV 64 ++I+CKAAV WE KP IEEVEVAPP+ HEVRIK++ +C +D + TPL P Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG-T 123 I GHEA GIVESVGEGVT ++PGD V+P+FT +CG+CR C + ESN C + RG Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + DG RF+ +GKPI+HF+G STFS+YTVV VAKI+ +PL+KVC++ CG STG G+ Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 + VAK G + A+FGLG VGL G + AGA+RII VD N +F +AKE G TEC+N Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 P+D+ KPIQ+V+ EMTDGGVD S E G + M+ + C H+ G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 304 INPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLL 363 +PM L RT KG FG +K K +P +V +M K+ L+ IT+ +PF +IN+ FD + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 364 RSGKSIRTVLTF 375 G+SIR ++T Sbjct: 362 LKGESIRCIITM 373 >1E3E-A nrPDB Length = 376 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 203/378 (53%), Positives = 268/378 (70%), Gaps = 6/378 (1%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 61 T GKVIKCKAA+ W+ P IEE+EV+PPKA EVRI+++A +C +D + Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP- 120 PV+LGHE AGIVESVG GVT KPGDKVIP F PQC +C++C +P +N C K Sbjct: 61 FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYP 120 Query: 121 ---RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 177 + ++D T RFTC G+ I+HF+GVS+FSQYTVV E +A++D + LE+VCLIGCGF Sbjct: 121 TIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGF 180 Query: 178 STGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 S+GYG+A+ AKVTPGSTCAVFGLG VGLS ++GCK AGA+RIIA+DIN +KF KAK LG Sbjct: 181 SSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALG 240 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 AT+C+NP++ KP+Q+V+ E+T GGVD+S + G T+ A++ C G+ +VG Sbjct: 241 ATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKV 300 Query: 298 DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKIN 357 D + ++L GR+ G FGG+KS +SVP LV+D+ KKF LD L+T+ LPFE IN Sbjct: 301 DEMTIPTVDVIL--GRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIN 358 Query: 358 EGFDLLRSGKSIRTVLTF 375 + DL++ GKSIRT+LTF Sbjct: 359 DAIDLMKEGKSIRTILTF 376 >1P0F-A nrPDB Length = 373 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 220/375 (58%), Positives = 286/375 (76%), Gaps = 2/375 (0%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60 M TAGK I CKAAV WE KP S+E + VAPPKAHEVRIK++A+GIC SD V+ + + Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 PVILGHEA G+VES+G GVT VKPGDKVIPLF PQCG CR CK+ SN+C KND+G Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + D T RFTC GKPI++ +G STF++YTVV + AVAKID +PLE CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AV AKVTPGSTCAVFGLGGVG S ++GCKAAGA+RII V +KDKF KA ELGATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 C+NP+DY KPI EV+ E T+GGVD++ E GR++TMM +L + G +V++G+ ++ Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360 L ++P+LLLTGR+ KG++FGGFK E V +LV D+M KK +++ L++ L ++IN+ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 361 DLLRSGKSIRTVLTF 375 +LL SG+ +R+++ + Sbjct: 359 ELLSSGQGVRSIMIY 373 >3PII-A nrPDB Length = 339 Score = 309 bits (792), Expect = 1e-84, Method: Composition-based stats. Identities = 120/369 (32%), Positives = 165/369 (44%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV--TPLPVILGH 68 KAAV+ + K+P I+EVE EV +++ A G+C +D H G+ LP+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E GIVE VG GVT +K GD+V IP CG C C + + C G DG Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNA---GYSVDG 118 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 +++Y + V KI E+ I C T Y A+KV Sbjct: 119 ------------------GYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALKV 159 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A++G+GG G V KA G ++AVDI +K AKELGA +NP Sbjct: 160 TGAKPGEWVAIYGIGGFGHVAVQYAKAMG-LNVVAVDIGDEKLELAKELGADLVVNP--L 216 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 K+ + +KE GGV + V S G V+VG+PP+ + I Sbjct: 217 KEDAAKFMKEKV-GGVHAAV-VTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDT 274 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 +L G G+I G K + + A+ K I + P EKINE FD + G+ Sbjct: 275 -VLNGIKIIGSIVGTRKDLQEALQFAAEGKVK------TIIEVQPLEKINEVFDRMLKGQ 327 Query: 368 -SIRTVLTF 375 + R VLT Sbjct: 328 INGRVVLTL 336 >5TNX-A nrPDB Length = 383 Score = 298 bits (762), Expect = 3e-81, Method: Composition-based stats. Identities = 124/358 (34%), Positives = 177/358 (49%), Gaps = 8/358 (2%) Query: 19 KKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVG 78 PFSIE + P+ EV +++VA G+C +D V PLP +LGHE AG+VE+VG Sbjct: 27 GAPFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVG 86 Query: 79 EGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTR--RFTCSGK 136 V T+ GD V+ L CG C C YC + N G DG R Sbjct: 87 PNVKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEP 145 Query: 137 PIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTC 196 HF S+F+ Y + EN K+ +PLE + +GCG TG G+ + V GS+ Sbjct: 146 LHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSF 205 Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 A FG G VG+S VM + AGA IIAVDI + A A ELGAT IN ++ + + ++ Sbjct: 206 ASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIR 263 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN-PMLLLTGRTW 315 E+T GGVD++ E G + + GT +VG P + LLL G T Sbjct: 264 EITGGGVDYALESTGLPAVLSQGIDALGSR-GTMGVVGAPKLGTKAEFDVNSLLLGGHTI 322 Query: 316 KGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVL 373 +G + G + +P+LV + +F D L+ P E+IN+ SG +++ +L Sbjct: 323 RGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLV-KFYPLEQINQAAADSSSGITLKPIL 379 >1F8F-A nrPDB Length = 371 Score = 297 bits (761), Expect = 4e-81, Method: Composition-based stats. Identities = 121/366 (33%), Positives = 188/366 (51%), Gaps = 10/366 (2%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAA 71 AAV F ++ +++ P+ EV +K+VA G+C +D V PLP +LGHE + Sbjct: 9 AAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGS 68 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 GI+E++G VT ++ GD V+ L CGKC C YC + N G +G Sbjct: 69 GIIEAIGPNVTELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHAL 127 Query: 132 TCSGKPI--HHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 + + HF S+F+ Y + EN K+ P+E + +GCG TG G+ + K Sbjct: 128 CTHDQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALK 187 Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 VTP S+ +G G VGLS ++ K GA+ IIAVDI + + AK+LGAT IN + + Sbjct: 188 VTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK-TQD 246 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP--PDSQNLSINPM 307 P+ + KE+TDGGV+F+ E G + + + G +VG P + +N Sbjct: 247 PVAAI-KEITDGGVNFALESTGSPEILKQGVDALG-ILGKIAVVGAPQLGTTAQFDVND- 303 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 LLL G+T G + G K+ +P+LV + KF D L+ F++IN+ R G Sbjct: 304 LLLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGI 362 Query: 368 SIRTVL 373 +++ ++ Sbjct: 363 TLKPII 368 >3MEQ-A nrPDB Length = 365 Score = 296 bits (757), Expect = 1e-80, Method: Composition-based stats. Identities = 106/371 (28%), Positives = 150/371 (40%), Gaps = 36/371 (9%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVIL 66 KAAV+ KP +I+EV + P ++++ + A+G+C +D H G+ P I Sbjct: 25 TMKAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIP 84 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG GV VK GD+V IP CG CR C C + Sbjct: 85 GHEGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEE----------- 133 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + + F++Y V D N V + ++ + C T Y + Sbjct: 134 ----------QLNTGYSVNGGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGL 182 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 KV PG + G+GG+G V +A G + AVDI+ K A+ LGAT +N + Sbjct: 183 KVTDTKPGDWVVISGIGGLGHMAVQYARAMG-LNVAAVDIDDRKLDLARRLGATVTVNAK 241 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN 305 P + KE TDGG +L GT + G+PP LSI Sbjct: 242 TVADPAAYIRKE-TDGGAQGVLVTAVSPKAFEQALGMVAR-GGTVSLNGLPPGDFPLSIF 299 Query: 306 PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRS 365 M +L G T +G+I G + AD K E IN FD +R Sbjct: 300 NM-VLNGVTVRGSIVGTRLDLQESLDFAADGKVKATIQTG------KLEDINAIFDDMRQ 352 Query: 366 G-KSIRTVLTF 375 G R V+ Sbjct: 353 GNIEGRIVMDL 363 >4Z6K-A nrPDB Length = 346 Score = 290 bits (741), Expect = 9e-79, Method: Composition-based stats. Identities = 110/369 (29%), Positives = 163/369 (44%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGH 68 KAAVL E + IEEV++ P A E+ +KM A+G+C +D H V G+ P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G++ +VGEGVT VK GD+V + CG C C C Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNS--------- 112 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 + +F++Y + + N V I + ++ + C T Y +K+ Sbjct: 113 ------------GYSVNGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKM 159 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G V A G + AVDI+ DK A AK+LGA +N ++ Sbjct: 160 TDTKPGDWVVISGIGGLGHMAVQYAIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKN- 217 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 P + + KE+ GG + V L GT V G+PP +SI Sbjct: 218 TDPAEYLQKEI--GGAHGAL-VTAVSAKAFDQALSMLRRGGTLVCNGLPPGDFPVSIFDT 274 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 +L G T +G+I G + + MA + A +T P E IN+ F+ +R GK Sbjct: 275 -VLNGITIRGSIVGTRLDLQE-----SLDMAAAGKVKATVTAE-PLENINDIFERMRQGK 327 Query: 368 -SIRTVLTF 375 R V+ + Sbjct: 328 IEGRIVIDY 336 >1LLU-A nrPDB Length = 342 Score = 288 bits (736), Expect = 4e-78, Method: Composition-based stats. Identities = 100/371 (26%), Positives = 156/371 (42%), Gaps = 38/371 (10%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV--TPLPVIL 66 KAAV+ P IEEV+V P +V +K+ A+G+C +D H G+ PLP I Sbjct: 6 TMKAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIP 65 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG GVT VK GD+V IP CG C C C Sbjct: 66 GHEGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNT------- 118 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + +++Y + D N V + ++ I C T Y + Sbjct: 119 --------------GYSVNGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGL 163 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 K PG A+ G+GG+G V +A G + A+DI+ K A++LGA+ +N + Sbjct: 164 KQTNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVNAR 222 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN 305 + P++ + +++ GG V ++ + GT +VG+PP I Sbjct: 223 Q-EDPVEAIQRDI--GGAHGVL-VTAVSNSAFGQAIGMARRGGTIALVGLPPGDFPTPIF 278 Query: 306 PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRS 365 ++L G G+I G + A + + A I + + IN+ D +R+ Sbjct: 279 D-VVLKGLHIAGSIVGTRADLQEALDF-----AGEGLVKATI-HPGKLDDINQILDQMRA 331 Query: 366 GK-SIRTVLTF 375 G+ R VL Sbjct: 332 GQIEGRIVLEM 342 >2DFV-A nrPDB Length = 347 Score = 284 bits (727), Expect = 3e-77, Method: Composition-based stats. Identities = 99/374 (26%), Positives = 156/374 (41%), Gaps = 37/374 (9%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL----VTPLPV 64 K A + + + EV+V P EV IK++A IC +D H+ N P Sbjct: 3 KMVAIMKTKPGYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQ 62 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTL 124 I+GHE AG V +G GV ++ GD V CGKC C+ + + C + G Sbjct: 63 IMGHEVAGEVVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKI---FGVD 119 Query: 125 QDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184 DG F++Y VV + K + P E L G+A Sbjct: 120 TDGV------------------FAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNA 156 Query: 185 VKVAKVTP--GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 V P G + + G G +GL + KA+GA +I + + + AK++GA I Sbjct: 157 VDTVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVI 216 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 NP + + ++EV+ GVD E G + L A G ++G+ P + Sbjct: 217 NPFE-EDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTI 274 Query: 303 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFD 361 N +++ T G G E+ + + K +LD +IT+ F+K E F+ Sbjct: 275 DFNNLIIFKALTIYG--ITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFE 332 Query: 362 LLRSGKSIRTVLTF 375 L+R+GK+ + V Sbjct: 333 LMRAGKTGKVVFML 346 >3S2F-A nrPDB Length = 340 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 104/369 (28%), Positives = 152/369 (41%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGH 68 KAAV+ P +I+EV V P +V++K+ A+G+C +D H G+ LP I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GV+ VK GD+V +P CG C C C K Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNT--------- 114 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 + + +Y V D N V + ++ I C T Y +KV Sbjct: 115 ------------GYSVNGGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKV 161 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G V +A G R+ AVDI+ K A+ LGA +N +D Sbjct: 162 TDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARD- 219 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 P + KE+ GG V + + GT + G+PP I Sbjct: 220 TDPAAWLQKEI--GGAHGVL-VTAVSPKAFSQAIGMVRRGGTIALNGLPPGDFGTPIFD- 275 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 ++L G T +G+I G + A + A ++ + +N+ F LR GK Sbjct: 276 VVLKGITIRGSIVGTRSDLQESLDF-----AAHGDVKATVS-TAKLDDVNDVFGRLREGK 329 Query: 368 -SIRTVLTF 375 R VL F Sbjct: 330 VEGRVVLDF 338 >3GFB-A nrPDB Length = 350 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 93/358 (25%), Positives = 149/358 (41%), Gaps = 37/358 (10%) Query: 23 SIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL----VTPLPVILGHEAAGIVESVG 78 + EV+V P EV IK++A IC +D H+ N P I+GHE AG V VG Sbjct: 18 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVG 77 Query: 79 EGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPI 138 GV ++ GD + CGKC CK+ + C + G DG Sbjct: 78 PGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKI---FGVDMDGV---------- 124 Query: 139 HHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP--GSTC 196 F+ Y +V K P E L G+AV P G + Sbjct: 125 --------FAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGRST 171 Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 + G G +GL + KA+GA +I + ++ + AK++GA +NP + + P++ V+ Sbjct: 172 LITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVKFVMD 230 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWK 316 GV+ E G + L G ++G+ P + N +++ Sbjct: 231 ITDGAGVEVFLEFSGAPKALEQGLKAVT-PGGRVSLLGLFPREVTIDFNNLIIFKALEVH 289 Query: 317 GAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRSGKSIRTVL 373 G G E+ + + + K +LD +IT+ F+K E F+L+R+GK+ + V Sbjct: 290 G--ITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >2EER-A nrPDB Length = 347 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 101/376 (26%), Positives = 155/376 (41%), Gaps = 43/376 (11%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG---------NLVTP 61 +A L E+ KP +E++ + PK +V IK+ AAG+C SD H+ G +L Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ S +E + C T Sbjct: 119 GINYDG------------------AYAEYVLVPHYKYLYKLRRLSAVE-AAPLTCSGVTT 159 Query: 181 YGSAVKVAKVTPGSTCAVFGLGG-VGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y AV+ A + P T V G GG +G + KA A II VD+ ++ AK GA Sbjct: 160 YR-AVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 IN + P+ E+ + G D ++ T+ + G V+VG+ Sbjct: 219 YVINAS-SQDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQ-GKYVMVGLFGAD 276 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 P++ L + G++ G + L A+ + ++T + E+ NE Sbjct: 277 LKYHA-PLITLNEVQFIGSLVGNQSDFLGIMSL-----AEAGKVKPMVTKTMKLEEANEA 330 Query: 360 FDLLRSGKS-IRTVLT 374 D L + K+ R VL Sbjct: 331 IDNLENFKAVGRQVLV 346 >6N7L-A nrPDB Length = 353 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 104/370 (28%), Positives = 153/370 (41%), Gaps = 39/370 (10%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV--TPLPVIL 66 KAAV+ +P I+EV V P +EV +K++A G+C +D H V G+ +P+I Sbjct: 13 TMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIP 72 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 GHE GIV + G VK GD V +P CG C C C G G Sbjct: 73 GHEGVGIVVACGPDA-MVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNG---GYSV 128 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 DG F++Y + D V + + ++ I C T Y + Sbjct: 129 DG------------------GFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGL 169 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 K + PG A+ G+GG+G V KA G + A+D+ DK AK+LGA +N + Sbjct: 170 KETETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVNAK 228 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN 305 P + KE+ GG+ + + GT + G+PP S L I Sbjct: 229 -TTDPGTYLHKEV--GGMHGALITAVSPIAFKQGID-VLRRKGTIALNGLPPGSFELPIF 284 Query: 306 PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRS 365 +L T +G+I G K + + + K A E IN+ FD ++ Sbjct: 285 ET-VLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSA------KLEDINDVFDKMKK 337 Query: 366 GK-SIRTVLT 374 G+ R VL Sbjct: 338 GQIDGRIVLD 347 >1PL8-A nrPDB Length = 356 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 88/366 (24%), Positives = 153/366 (41%), Gaps = 33/366 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGH 68 +++ +E + P +EV ++M + GIC SD H GN + P++LGH Sbjct: 10 SLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGH 69 Query: 69 EAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGT 128 EA+G VE VG V +KPGD+V CK N Sbjct: 70 EASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNL---------------SP 114 Query: 129 RRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA 188 F C+ P ++ + K+ E+ LI S G A + Sbjct: 115 SIFFCATPPDD-----GNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGIH-ACRRG 167 Query: 189 KVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-PQDY 247 VT G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + ++ Sbjct: 168 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 227 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 + I ++ + + E G ++ A + + GT V+VG+ ++ P+ Sbjct: 228 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT-RSGGTLVLVGL---GSEMTTVPL 283 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 L R I G F+ + P ++ +K ++ L+T+ P EK E F+ + G Sbjct: 284 LHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 341 Query: 368 SIRTVL 373 ++ +L Sbjct: 342 GLKIML 347 >3QE3-A nrPDB Length = 355 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 89/366 (24%), Positives = 158/366 (43%), Gaps = 33/366 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGH 68 +++ +E + P +EV +KM + GIC SD H G+ V P++LGH Sbjct: 9 SLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGH 68 Query: 69 EAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGT 128 EA+G V VG V ++PGD+V CK N Sbjct: 69 EASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNL---------------SP 113 Query: 129 RRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA 188 F C+ P ++ + N K+ E+ LI S G A + A Sbjct: 114 TIFFCATPPDD-----GNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGIH-ACRRA 166 Query: 189 KVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-PQDY 247 VT G+ V G G +GL ++ KA GAA+++ D++ + +KAKE+GA + + Sbjct: 167 GVTLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNES 226 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 + I + ++ + + + E G ++ A + H + GT V+VG+ + ++ Sbjct: 227 PEEIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATH-SGGTLVLVGLGSEMTSVP---- 281 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 L+ T + I G F+ + P ++ +K ++ L+T+ P EK E F+ + G Sbjct: 282 -LVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGL 340 Query: 368 SIRTVL 373 ++ ++ Sbjct: 341 GLKVMI 346 >2DQ4-A nrPDB Length = 343 Score = 263 bits (673), Expect = 7e-71, Method: Composition-based stats. Identities = 90/368 (24%), Positives = 156/368 (42%), Gaps = 33/368 (8%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN----LVTPLPVIL 66 +A ++ ++ + V P E+ +++ AA IC +D H+ + P++ Sbjct: 2 RALAKLAPEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVT 61 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 GHE +G+VE+VG GV + GD V C C C+ + CL + G +D Sbjct: 62 GHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQI---LGVDRD 118 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 G F++Y VV P E V I F + Sbjct: 119 G------------------GFAEYVVVPAENAWVNPKDLPFE-VAAILEPFGNAVHTVYA 159 Query: 187 VAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 + V+ G + + G G +GL M +A+GA I+ D N + A A+ A +NP Sbjct: 160 GSGVS-GKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP-- 215 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 ++ + EV++ +T GV+ E G + L+ G + I+G+P D + Sbjct: 216 LEEDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALI-PGGEARILGIPSDPIRFDLAG 274 Query: 307 MLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 L++ G T G G + ++ + A + + L L+T+ LP + E F LL SG Sbjct: 275 ELVMRGITAFG--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASG 332 Query: 367 KSIRTVLT 374 ++++ +L Sbjct: 333 QAVKVILD 340 >5KIA-A nrPDB Length = 351 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 86/370 (23%), Positives = 151/370 (40%), Gaps = 36/370 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN----LVTPLPVIL 66 KA E ++ V+ ++V IK+ IC +D H+ + P+P+ + Sbjct: 10 KALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHV 69 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 GHE G + +G+ V GD+V CG CR C+ + C R T+ Sbjct: 70 GHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLC--------RNTVGV 121 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 G R F++Y + KI + + I F +A+ Sbjct: 122 GVNRE-------------GAFAEYLAIPAFNAFKIPPEIS-DDLAAIFDPFGNATHTALS 167 Query: 187 VAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 V G + G G +G+ V K GA ++ DIN + A+ +GAT +N Sbjct: 168 FNLV--GEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVS- 224 Query: 247 YKKPIQEVLKEM-TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN 305 ++ +++V+ ++ G D E+ G + + SLL G ++G+PP + N Sbjct: 225 -RESLRDVMADLHMTEGFDVGLEMSG-VPSAFTSLLESMNHGGKVALLGIPPAQTAIDWN 282 Query: 306 PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRS 365 ++ G KG G + E+ K+VA + L +IT+ + +GF + S Sbjct: 283 -QVIFKGLEIKGIY--GREMFETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFAAMLS 338 Query: 366 GKSIRTVLTF 375 G+S + +L + Sbjct: 339 GESGKVILDW 348 >4CPD-A nrPDB Length = 347 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 92/364 (25%), Positives = 162/364 (44%), Gaps = 24/364 (6%) Query: 13 AVLWELKKPFSIEEVEVAPPK-AHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAA 71 AV++E K+ +++EV + + +++ AGIC SD H+ G + +LGHE Sbjct: 3 AVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHEFV 62 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G VE+VGEG+ ++PGD V+ F CG C C+ + N C + + G Sbjct: 63 GQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGV--------YGYGPM 114 Query: 132 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVT 191 + + + FS + K+ E+ G ST YG ++ ++ Sbjct: 115 FGNLQGAQAEILRVPFSNV------NLRKLPPNLSPERAIFAGDILSTAYGGLIQ-GQLR 167 Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 PG + AV G G VGL + + GA++I+A+D ++ +A LGA IN + + P+ Sbjct: 168 PGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQ-ENPV 225 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLT 311 + V E D G D E +G T+ +L G VGV N P L + Sbjct: 226 RRVRSETNDEGPDLVLEAVGGAATLSLALE-MVRPGGRVSAVGV----DNAPSFPFPLAS 280 Query: 312 GRTWKGAIFGGFKSKE-SVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIR 370 G G + + ++A + + + ++++ LP E+ G++L ++++ Sbjct: 281 GLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDRKEALK 340 Query: 371 TVLT 374 +L Sbjct: 341 VLLV 344 >4EEZ-A nrPDB Length = 348 Score = 257 bits (656), Expect = 6e-69, Method: Composition-based stats. Identities = 98/368 (26%), Positives = 154/368 (41%), Gaps = 34/368 (9%) Query: 11 KAAVLWELKKPF-SIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHE 69 KAAV+ + + E E+ K +E + M G+C +D HV +G+ +LGHE Sbjct: 2 KAAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHE 61 Query: 70 AAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGT 128 GIV+ +G V++++ GD+V + F CG C C + +C + G DG Sbjct: 62 GIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNA---GYSVDG- 117 Query: 129 RRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA 188 ++ +V + K+ + I C T Y A+KV+ Sbjct: 118 -----------------GMAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTY-KAIKVS 159 Query: 189 KVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 V PG +FG GG+G + K A++IAVDIN+DK AK++GA IN D Sbjct: 160 GVKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDV- 218 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPML 308 P+ E+ K GV + + + G V V VP LS+ P + Sbjct: 219 NPVDEIKKITGGLGVQSAIVC-AVARIAFEQAVASLKPMGKMVAVAVPNTEMTLSV-PTV 276 Query: 309 LLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK- 367 + G G++ G + A+ K I E+IN+ D +++GK Sbjct: 277 VFDGVEVAGSLVGTRLDLAEAFQFGAEGKVKP------IVATRKLEEINDIIDEMKAGKI 330 Query: 368 SIRTVLTF 375 R V+ F Sbjct: 331 EGRMVIDF 338 >1H2B-A nrPDB Length = 359 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 94/378 (24%), Positives = 170/378 (44%), Gaps = 42/378 (11%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAP-PKAHEVRIKMVAAGICRSDEHVVSGNL----VTP 61 V + KAA L E KP IE+V+ +V +++ AG+C +D H+V G Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LP LGHE G +E V EGV ++ GD VI G C C+ E +C + Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEF---P 129 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKV---CLIGCGFS 178 G DG F+++ +V K+ EK+ + Sbjct: 130 GLNIDG------------------GFAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGI 171 Query: 179 TGYGSAVKVAK-VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 T Y + K A+ + PG+ A+ G+GG+G V K A +IA+D+ ++K A+ LG Sbjct: 172 TAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLG 231 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 A ++ + + P+++V++ GV+ + + +G T+ + G +IVG Sbjct: 232 ADHVVDAR--RDPVKQVMELTRGRGVNVAMDFVGSQATVDYTPYLLGR-MGRLIIVGYGG 288 Query: 298 DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKIN 357 + + +I ++ + +++G++ G + + +LV + K ++ +I ++IN Sbjct: 289 ELRFPTIR--VISSEVSFEGSLVGNYV---ELHELVTLALQGKVRVE---VDIHKLDEIN 340 Query: 358 EGFDLLRSGKSI-RTVLT 374 + + L G+ + R VL Sbjct: 341 DVLERLEKGEVLGRAVLI 358 >1R37-A nrPDB Length = 347 Score = 250 bits (639), Expect = 6e-67, Method: Composition-based stats. Identities = 105/376 (27%), Positives = 159/376 (42%), Gaps = 43/376 (11%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG---------NLVTP 61 +A L E+ KP S++E+ V PK +V IK+ AAG+C SD H+ G +L Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ + +E + C T Sbjct: 119 GINFDG------------------AYAEYVIVPHYKYMYKLRRLNAVE-AAPLTCSGITT 159 Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGL-SVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y AV+ A + P T V G GG V KA A II VD+ ++ AK GA Sbjct: 160 YR-AVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 IN + P+ E+ + GVD ++ T+ + G V+VG+ Sbjct: 219 YVINAS-MQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQ-GKYVMVGLFGAD 276 Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 + P++ L+ + G++ G + +L A+ + +IT + E+ NE Sbjct: 277 LHYHA-PLITLSEIQFVGSLVGNQSDFLGIMRL-----AEAGKVKPMITKTMKLEEANEA 330 Query: 360 FDLLRSGKSI-RTVLT 374 D L + K+I R VL Sbjct: 331 IDNLENFKAIGRQVLI 346 >5YLN-A nrPDB Length = 356 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 94/368 (25%), Positives = 157/368 (42%), Gaps = 34/368 (9%) Query: 15 LWELKKPFSIEEVEVAPP---KAHEVRIKMVAAGICRSDEHVVSGNLVT-PLPVILGHEA 70 + KP V+V P K + +++V IC +D H++ G++ T ILGHE Sbjct: 7 AYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEG 66 Query: 71 AGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRR 130 GIVE VGEGV+ K GDKV+ CGKC CK +C ++ G G L DG + Sbjct: 67 IGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCE-DEGGWIFGHLIDGMQ- 124 Query: 131 FTCSGKPIHHFVGVSTFSQYTVVD--ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA 188 ++Y V +N + E + ++ TGY V Sbjct: 125 -----------------AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKG 167 Query: 189 KVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 KV PG + A+ G G VGL+ ++ + A++I VD++ ++ A GAT +N D + Sbjct: 168 KVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPE 227 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPML 308 K I+E+ GVD + E +G T GT GV ++ + Sbjct: 228 KAIKEIYDLTDGRGVDVAIEAVGIPATFDFC-QKIIGVDGTVANCGVHGKPVEFDLDKLW 286 Query: 309 LLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG-- 366 + + G S + P+L+ + K + L+T+ +I + +++ Sbjct: 287 I-----RNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAAD 341 Query: 367 -KSIRTVL 373 +I+ ++ Sbjct: 342 HHAIKVII 349 >5ENV-A nrPDB Length = 347 Score = 244 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 96/369 (26%), Positives = 149/369 (40%), Gaps = 36/369 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGH 68 K + +E +++ V PKA+E+ I + +G+C +D H G+ P LP++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E AG+V +GE V K GD I C C C+ + C DL G DG Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADL---SGYTHDG 123 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 +F QY D A I + L +V I C T Y A+K Sbjct: 124 ------------------SFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKS 164 Query: 188 AKVTPGSTCAVFG-LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG+G V KA G R++ +D + K + +G I+ Sbjct: 165 ANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTK 223 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 K + VLK TDGG V + AS A GT+V+VG+P ++ S Sbjct: 224 EKDIVGAVLKA-TDGGAHGVINVSVSEAAIEASTRYV-RANGTTVLVGMPAGAKCCSDVF 281 Query: 307 MLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 ++ + G+ G DF A+ + ++ + E ++ + G Sbjct: 282 NQVVKSISIVGSYVGNRADTRE----ALDFFARGLVKSPI--KVVGLSTLPEIYEKMEKG 335 Query: 367 K-SIRTVLT 374 + R V+ Sbjct: 336 QIVGRYVVD 344 >5VM2-A nrPDB Length = 347 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 91/352 (25%), Positives = 143/352 (40%), Gaps = 34/352 (9%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEH-VVSGNLVTPL----PVILGHE 69 + ++ I E+ PK EV IK+ GIC SD H SG + P + LGHE Sbjct: 7 ILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHE 66 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTR 129 AG V +VG V KPGD+V CG CR C + N C D + + Sbjct: 67 CAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYR---- 122 Query: 130 RFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 + Y E+ K+ + L+ + G +A+ +A Sbjct: 123 ---------------GALTHYLCHPESFTYKLPDNMDTMEGTLVEPA-AVGMHAAM-LAD 165 Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 V PG + G G +GL + CK GA I VD+ + + A A++LGAT IN + Sbjct: 166 VKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAK-ED 224 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 309 I + D G D FE G T+ + G +IVG P + +IN + + Sbjct: 225 TIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMR-GGKIMIVGTVPGAS--AINFLKI 281 Query: 310 LTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFD 361 T + F+ P + + +F + +++T+I + + + F+ Sbjct: 282 NREVTIQTV----FRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >1UUF-A nrPDB Length = 369 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 90/371 (24%), Positives = 147/371 (39%), Gaps = 32/371 (8%) Query: 8 IKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPLPVIL 66 +K KA + K+P ++ P ++V+I++ G+C SD H V T P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG+ V PGD V + C C C++ NYC Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDH----------M 130 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKID-AASPLEKVCLIGCGFSTGYGSA 184 GT +P H +SQ VV E V +I L V + C T Y Sbjct: 131 TGTYNSPTPDEPGHTL---GGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSP- 186 Query: 185 VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 ++ + PG V G+GG+G + A GA ++A ++ K AK LGA E +N Sbjct: 187 LRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGA-HVVAFTTSEAKREAAKALGADEVVNS 245 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304 ++ + + DF + + + GT +VG P Sbjct: 246 RNADEMAAHL------KSFDFILNTVAAPHNLDD-FTTLLKRDGTMTLVGAPATPHKSPE 298 Query: 305 NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364 L++ R G++ GG + + DF A+ + + ++ ++INE ++ + Sbjct: 299 VFNLIMKRRAIAGSMIGGIPETQE----MLDFCAEHGIVADI--EMIRADQINEAYERML 352 Query: 365 SGK-SIRTVLT 374 G R V+ Sbjct: 353 RGDVKYRFVID 363 >5H82-A nrPDB Length = 389 Score = 237 bits (605), Expect = 5e-63, Method: Composition-based stats. Identities = 79/336 (23%), Positives = 128/336 (38%), Gaps = 17/336 (5%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSGNLVT-PLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 H+V+ K++ G+C D T P + GHE GIV +G V K GDKV Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVG 111 Query: 91 IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQY 150 + F CGKC C YC K + D +S Sbjct: 112 VGNFIGSCGKCERCNEGLEPYCPKV-IYTDGTAFSDENNTVYGDVSGDGEDRIYGGYSNI 170 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 V +E V + PL I CG Y PG + V G G +G V Sbjct: 171 MVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLAVK 230 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 KA GA + K ++ G + ++ ++ + + +D F+ + Sbjct: 231 FAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEE------MKAAESTLDGIFDCV 284 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVP 330 + + LL + GT V++GV ++ L ++P LL+ R + G+I G K + Sbjct: 285 PSVHP-LHPLLNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMKETQE-- 340 Query: 331 KLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 + DF AK + + ++P + +N + + G Sbjct: 341 --MLDFAAKHNIVSDI--ELIPMDYVNTALERIAKG 372 >4EJ6-A nrPDB Length = 370 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 89/364 (24%), Positives = 146/364 (40%), Gaps = 30/364 (8%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAG 72 AV E S+ V + P ++ +K+ A GIC +D H++ G + PV LGHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 IV G V + PG ++ CG+C C+ N C G +DG Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLR---AIGIHRDG----- 137 Query: 133 CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP 192 F++Y +V +I L+ V C V ++ + Sbjct: 138 -------------GFAEYVLVPRKQAFEIP--LTLDPVHGAFCEPLACCLHGVDLSGIKA 182 Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKP 250 GST A+ G G +GL V + AGA +I K A+E+GAT ++P D + Sbjct: 183 GSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEA 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 I + + GGVD E G +T+ S +A GT VI+GV P + + I P +L Sbjct: 243 IAGPVG-LVPGGVDVVIECAGVAETVKQSTR-LAKAGGTVVILGVLPQGEKVEIEPFDIL 300 Query: 311 TGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIR 370 + G F + + +D +I+ + ++ + + ++ Sbjct: 301 FRELR---VLGSFINPFVHRRAADLVATGAIEIDRMISRRISLDEAPDVISNPAAAGEVK 357 Query: 371 TVLT 374 ++ Sbjct: 358 VLVI 361 >1E3J-A nrPDB Length = 352 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 81/372 (21%), Positives = 149/372 (40%), Gaps = 39/372 (10%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILG 67 +AVL++ +E+ + PK EV ++M GIC SD H + + P+++G Sbjct: 7 SAVLYKQND-LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 HEA+G V VG+ V +K GD+V C +C+ CK + N C Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTF---------- 115 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 C+ P ++Y V + K+ LE+ L+ S G A + Sbjct: 116 -----CATPPDD-----GNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGVH-ACRR 163 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN---P 244 A V G+T V G G +GL V+ KA GA ++ + + AK GA + Sbjct: 164 AGVQLGTTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPA 222 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304 ++ + I E ++ + + + G + + GT ++VG+ + Sbjct: 223 KEEESSIIERIRSAIGDLPNVTIDCSGNEKCITIGI-NITRTGGTLMLVGMGSQMVTVP- 280 Query: 305 NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364 L+ + I F+ P + + + ++ L+T+ E+ + F+ R Sbjct: 281 ----LVNACAREIDIKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFEAAR 336 Query: 365 S--GKSIRTVLT 374 +I+ +++ Sbjct: 337 KKADNTIKVMIS 348 >1YKF-A nrPDB Length = 352 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 96/351 (27%), Positives = 154/351 (43%), Gaps = 34/351 (9%) Query: 24 IEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVT 82 E E P + ++ +A C SD H V G + +ILGHEA G V VG V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 83 TVKPGDKVI-PLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 KPGD+V+ P TP + + + G ++DG Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQHS-GGMLAGWKFSNVKDGV------------- 119 Query: 142 VGVSTFSQYTVVDE--NAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF 199 F ++ V++ +A + PLE +I +TG+ A ++A + G+T AV Sbjct: 120 -----FGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVL 173 Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G+G VGL V G K GA RIIAV AK GAT+ +N +D PI+ + +T Sbjct: 174 GIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLT 231 Query: 260 DG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRTW 315 +G GVD + G D +MA+ + + GT V + + L + + + +T Sbjct: 232 EGKGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTI 290 Query: 316 KGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 KG + G + + +L+ K+ L+T++ F+ I + F L++ Sbjct: 291 KGGLCPGGRLRME--RLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >4GKV-A nrPDB Length = 336 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 102/367 (27%), Positives = 155/367 (42%), Gaps = 36/367 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEA 70 KAAV+ + + + K E +KM G+C +D HV +G+ VILGHE Sbjct: 2 KAAVVTKDHH-VDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEG 60 Query: 71 AGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTR 129 G+V VG GVT++KPGD+ + F CG C C + C G DG Sbjct: 61 IGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNA---GYSVDG-- 115 Query: 130 RFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 ++ +V + K+ I C T Y AVK++K Sbjct: 116 ----------------GMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTY-KAVKLSK 158 Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 + PG A++GLGG+G + K A++IA+D+N ++ A E+GA IN + + Sbjct: 159 IRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTE 216 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 309 ++++E T G V S + A G V VG+PP+S +L I P L+ Sbjct: 217 DAAKIVQEKTGGAHAAV--VTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLV 273 Query: 310 LTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK-S 368 L G G++ G + + A+ K + P IN F + GK Sbjct: 274 LDGIEVVGSLVGTRQDLTEAFQFAAE---GKVVPK---VALRPLADINTIFTEMEEGKIR 327 Query: 369 IRTVLTF 375 R V+ F Sbjct: 328 GRMVIDF 334 >5YAT-A nrPDB Length = 350 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 91/360 (25%), Positives = 142/360 (39%), Gaps = 35/360 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV--TPLPVILGH 68 KA + P +++ V PK++E+ I + +G+C +D H G+ LP++ GH Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGH 69 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E AG+V + GE VT + GD I C C C + C K DL Sbjct: 70 EGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLS--------- 120 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 F +F QY D A+I + L +V I C T Y A+K Sbjct: 121 ------------GFTHDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALKT 167 Query: 188 AKVTPGSTCAV-FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ GG+G V KA G R++ +D DK K LGA ++ Sbjct: 168 ADLRIGQWVAISGAGGGLGSLAVQYAKALG-LRVLGIDGGADKGEFVKSLGAEVFVDFTK 226 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 K + EV K +T+GG V + S+ G V+VG+P + S Sbjct: 227 TKDVVAEVQK-LTNGGPHGVINVSVSPHAINQSVQYV-RTLGKVVLVGLPSGAVVNSDVF 284 Query: 307 MLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 +L KG+ G + L + K I+ ++ + ++ + +G Sbjct: 285 WHVLKSIEIKGSYVGNREDSAEAIDLFTRGLVKAPI------KIIGLSELAKVYEQMEAG 338 >3FPL-A nrPDB Length = 351 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 95/352 (26%), Positives = 151/352 (42%), Gaps = 32/352 (9%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEG 80 E E +++ ++ +A C SD H V G L +ILGHEA G V VG Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 81 VTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHH 140 V KPGD+VI T + + + G +DG Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGV------------ 119 Query: 141 FVGVSTFSQYTVVDE--NAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAV 198 F +Y V++ +A + PLE +I +TG+ A ++A + G+T AV Sbjct: 120 ------FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAV 172 Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G+G VGL V G K GA RIIAV AK GAT+ +N +D PI+ + + Sbjct: 173 LGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNL 230 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRT 314 T+G GVD + G D +MA+ + + GT V + + L + + + +T Sbjct: 231 TEGKGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKT 289 Query: 315 WKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 KG + G + + + + + + L L+T++ F+ I E L++ Sbjct: 290 IKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKD 339 >4OH1-A nrPDB Length = 351 Score = 228 bits (580), Expect = 4e-60, Method: Composition-based stats. Identities = 88/367 (23%), Positives = 144/367 (39%), Gaps = 47/367 (12%) Query: 20 KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV-------TPLPVILGHEAAG 72 + E + PK E+RIK+V A IC SD H+++GNL + LP+ GHE +G Sbjct: 19 GTVDMMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSG 78 Query: 73 IVESVGEGVT--TVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRR 130 +++ VG K G KV+ + CG C C+ + N C Sbjct: 79 VIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGYR------------ 126 Query: 131 FTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKV 190 ++ FS+Y V + + I + L+ L+ + SA + AK+ Sbjct: 127 -------------MNGFSEYAVYHMSQIFPIPDDADLKDYALVE-PLTVALSSAEQ-AKI 171 Query: 191 TPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 + G + A+ G GG+G+ +V + AGA+ I DI +K A E GA +N + + Sbjct: 172 SYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EG 229 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN--PML 308 + E E+ G D E G L G +V + L +N L Sbjct: 230 VAERAIELAGGRYDCVLEGTGATAAAKLGLQLLAR-DGDAVYFAMYGKDPILPVNLQSDL 288 Query: 309 LLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKS 368 + G I G ++ +S+ M + +I + F+ L S K Sbjct: 289 YWDQKHIHGMIQGAWQFPKSIR------MIPRMDFSKIIQKEHTLTNYKQAFEDLYSKKY 342 Query: 369 IRTVLTF 375 + V+ Sbjct: 343 AKIVIKM 349 >5K1S-A nrPDB Length = 362 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 97/370 (26%), Positives = 154/370 (41%), Gaps = 36/370 (9%) Query: 11 KAAVLWELKK--PFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV-TPLPVILG 67 KA VL + +E + + P EV +++ A G+C D GNL T +P ILG Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 HEAAG V VG K GD+ L CG C +C++ ++ C ++ Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDN----------- 127 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 RF P ++Q+ V + ++ A+ P + + C T + Sbjct: 128 --RFFGEELP-------GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTR 178 Query: 188 AKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 KV G T + G GGVGLS V + GA R+IAV ++ K KE GA E I + Sbjct: 179 GKVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSRG 237 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 +V K GVD + E++G L G V+VG +S + +NP Sbjct: 238 L-DFASDVRKRTQGAGVDVAVEIVGS--ATFDQTLKSMAPGGRVVVVG-NLESGMVQLNP 293 Query: 307 -MLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRS 365 ++++ GA + +L A ++F +T+ +P + + L + Sbjct: 294 GLVIVKELEILGAYATTQAELDEALRLTATGGVRQF-----VTDAVPLAEAAKAHFRLEN 348 Query: 366 GK-SIRTVLT 374 + + R VL Sbjct: 349 REVAGRLVLV 358 >1YQX-A nrPDB Length = 366 Score = 224 bits (570), Expect = 6e-59, Method: Composition-based stats. Identities = 78/345 (22%), Positives = 130/345 (37%), Gaps = 31/345 (8%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSGNLV-TPLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 +VR K++ G+C SD H + + + P++ GHE G V VG V V GDKV Sbjct: 40 GEEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVG 99 Query: 91 IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQY 150 + C C C N NYC K + DGT + +S + Sbjct: 100 VGCLVGACHSCESCANDLENYCPKM-ILTYASIYHDGT-------------ITYGGYSNH 145 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 V +E + + PL+ + C T Y PG + GLGG+G V Sbjct: 146 MVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVK 205 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 KA G+ + K K GA + +D ++ + G +D + + Sbjct: 206 FAKAFGSKVTVISTSPSKKEEALKNFGADSFLVSRDQEQ------MQAAAGTLDGIIDTV 259 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVP 330 + ++ L ++ G ++VG P L L+ + G+ GG K + Sbjct: 260 SAVHPLL-PLFGLLKSHGKLILVGAPEKPLELPAFS-LIAGRKIVAGSGIGGMKETQE-- 315 Query: 331 KLVADFMAKKFSLDALITNILPFEKINEGFDLL-RSGKSIRTVLT 374 + DF AK + ++ + +N + L ++ R V+ Sbjct: 316 --MIDFAAKHNITADI--EVISTDYLNTAMERLAKNDVRYRFVID 356 >5Z0C-A nrPDB Length = 374 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 95/368 (25%), Positives = 134/368 (36%), Gaps = 34/368 (9%) Query: 13 AVLWELKKP---FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP-LPVILGH 68 AV W + P S +V K++ GIC SD H + P + GH Sbjct: 14 AVGWAARDPSGHLSPFTFSRRATGELDVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGH 73 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 E G V VG V K GDKV + C C C N NYC N + DG Sbjct: 74 EIVGEVTEVGSKVNKFKVGDKVGVGCIVGSCHSCPNCNNHLENYCP-NRILTFGSRYYDG 132 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187 T + +S VV E+ +I A PL+ + C T Y Sbjct: 133 T-------------LNHGGYSDLMVVQEHFAVRIPDALPLDSAAPLLCAGITVYSPLRYY 179 Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG V GLGG+G V KA G + K LGA I D Sbjct: 180 GLDKPGLHVGVVGLGGLGHMAVKFAKAFGVKVTVVSTSPAKKEDAISGLGAHSFILSTDA 239 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM 307 ++ V G +D + + + L+ ++ G V+VG PP L + P Sbjct: 240 EQMQAAV------GTMDGIIDTV-SASHPLPPLISLLKSHGKLVMVGDPPKPLELPVFP- 291 Query: 308 LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDL-LRSG 366 LLL + G+ GG K + + DF AK+ + ++P + +N +S Sbjct: 292 LLLGRKMVAGSAIGGMKETQE----MIDFAAKEGVRADV--EVIPMDYVNTAMQRVSKSD 345 Query: 367 KSIRTVLT 374 R V+ Sbjct: 346 VKYRFVID 353 >3FSR-A nrPDB Length = 352 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 87/350 (24%), Positives = 144/350 (41%), Gaps = 32/350 (9%) Query: 24 IEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVT 82 E E P + ++ +A C SD H V G + +ILGHEA G V VG V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 83 TVKPGDKVI-PLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 KPGD+V+ P TP + + + G ++DG Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQHS-GGMLAGWKFSNVKDGV------------- 119 Query: 142 VGVSTFSQYTVVDE--NAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF 199 F ++ V++ +A + PLE +I +TG+ A ++A + GS+ V Sbjct: 120 -----FGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVI 173 Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G+G VGL + G K GA RII V AK GAT+ +N ++ + +V+K Sbjct: 174 GIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTN 232 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRTWK 316 GVD G +T+ ++ + G + L I + + +T K Sbjct: 233 GKGVDRVIMAGGGSETLSQAV-SMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHKTIK 291 Query: 317 GAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 G + G + + +L+ K+ L+T++ F+ I + F L++ Sbjct: 292 GGLCPGGRLRME--RLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >3FPC-A nrPDB Length = 352 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 88/350 (25%), Positives = 141/350 (40%), Gaps = 32/350 (9%) Query: 24 IEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEGVT 82 E E P + ++ +A C SD H V G + +ILGHEA G V VG V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 83 TVKPGDKVI-PLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 KPGD+V+ P TP + + + G ++DG Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQHS-GGMLAGWKFSNVKDGV------------- 119 Query: 142 VGVSTFSQYTVVDE--NAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF 199 F ++ V++ +A + PLE +I +TG+ A ++A + G T V Sbjct: 120 -----FGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVI 173 Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G+G VGL V G GA RI AV K A E GAT+ IN ++ ++++LK Sbjct: 174 GIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN-GDIVEQILKATD 232 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRTWK 316 GVD G + T A + + V + N+ I + + Sbjct: 233 GKGVDKVVIAGGDVHT-FAQAVKMIKPGSDIGNVNYLGEGDNIDIPRSEWGVGMGHKHIH 291 Query: 317 GAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 G + G + + +L+ K+ L+T++ F+ I + F L++ Sbjct: 292 GGLCPGGRLRME--RLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >3TWO-A nrPDB Length = 348 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 100/365 (27%), Positives = 146/365 (40%), Gaps = 42/365 (11%) Query: 17 ELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP-LPVILGHEAAGIVE 75 E KP V +V I ++ AGIC SD H P+I GHE AGI++ Sbjct: 15 EHFKPHDFSRHAV---GPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIPGHEIAGIIK 71 Query: 76 SVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCS 134 VG+GV K GD V + F C C+ CK + +C K + C Sbjct: 72 EVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKV------------VFTYDCL 119 Query: 135 GKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGS 194 + + +S VVDEN V +D +PLEKV + C T Y +K +KVT G+ Sbjct: 120 DSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTYSP-LKFSKVTKGT 178 Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQE 253 V G GG+G V A GA + N+ K A +G +P+ K+ + Sbjct: 179 KVGVAGFGGLGSMAVKYAVAMGA-EVSVFARNEHKKQDALSMGVKHFYTDPKQCKEEL-- 235 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNLSINPMLLLT 311 DF I + L G +VG+PP + LS+ + L Sbjct: 236 ----------DFIISTIPTHYDLKDYLKLLT-YNGDLALVGLPPVEVAPVLSVFDFIHLG 284 Query: 312 GRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKS-IR 370 R G++ GG K + + K ++ I IL + I+ + L GK+ R Sbjct: 285 NRKVYGSLIGGIKETQEMVDFSI-----KHNIYPEIDLILG-KDIDTAYHNLTHGKAKFR 338 Query: 371 TVLTF 375 V+ Sbjct: 339 YVIDM 343 >4OAQ-A nrPDB Length = 367 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 83/368 (22%), Positives = 146/368 (39%), Gaps = 36/368 (9%) Query: 16 WELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL--VTPLPVILGHEAAGI 73 W K S E ++ P H+V +K G+C SD H +S + +++GHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 74 VESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 V +VG+ VT K GD+V I + C C+ C + YC + G + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ------------GAATYN 124 Query: 133 CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP 192 +++V +S +++ DE V I P + C T + ++ + Sbjct: 125 SKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDA 184 Query: 193 -GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G + G+GG+G + A GA + A + K +A +LGA + + + K Sbjct: 185 RGKNVGIIGIGGLGHLALQFANAMGA-NVTAFSRSSSKKEQAMKLGAHDFVATGEDKTWY 243 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTM-MASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 + D DF +D + ++ L + V VG+PP ++P L Sbjct: 244 KNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTFL 298 Query: 311 -TGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKIN--EGFDLLRSGK 367 G ++ ++ G + + L A K ++ +I + P + N + D +G Sbjct: 299 QQGASFGSSLLGSKTEVKEMLNL-----AAKHNVRPMIEEV-PISEENCAKALDRCHAGD 352 Query: 368 S-IRTVLT 374 R V T Sbjct: 353 VRYRFVFT 360 >1KEV-A nrPDB Length = 351 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 86/351 (24%), Positives = 141/351 (40%), Gaps = 30/351 (8%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLVTPLPVILGHEAAGIVESVGEG 80 E E +++ ++ +A C SD H V G L +ILGHEA G V VG Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 81 VTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHH 140 V KPGD+VI T + + + G +DG Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGV------------ 119 Query: 141 FVGVSTFSQYTVVDE--NAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAV 198 F +Y V++ +A + PLE +I +TG+ A ++A + GS+ V Sbjct: 120 ------FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVV 172 Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G+G VGL + G K GA RII V AK GAT+ +N ++ + +V+K Sbjct: 173 IGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLT 231 Query: 259 TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRTW 315 GVD G +T+ ++ + G + L I + + +T Sbjct: 232 NGKGVDRVIMAGGGSETLSQAV-SMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHKTI 290 Query: 316 KGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 KG + G + + + + + + L L+T++ F+ I E L++ Sbjct: 291 KGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKD 339 >2H6E-A nrPDB Length = 344 Score = 218 bits (555), Expect = 4e-57, Method: Composition-based stats. Identities = 96/378 (25%), Positives = 161/378 (42%), Gaps = 45/378 (11%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG---NLVTPLP 63 ++K KAA+L + +P SIE+V + P+ EV I++ AG+CR+D V G LP Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGT 123 +ILGHE AG + VGE + VK GD V+ T CR C+ + N C Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC----------- 108 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVV-DENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + I FS+Y +V + K+++ SP+E + +T G Sbjct: 109 ----------KNQIIPGQTTNGGFSEYMLVKSSRWLVKLNSLSPVE-AAPLADAGTTSMG 157 Query: 183 S---AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAG-AARIIAVDINKDKFAKAKELGA 238 + A+ V G+GG+ + + KA I+ + +K A ELGA Sbjct: 158 AIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFALELGA 217 Query: 239 TECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 +D + ++ ++TDG G + +++G +T +L G ++VG+ Sbjct: 218 DYVSEMKD----AESLINKLTDGLGASIAIDLVGTEETT-YNLGKLLAQEGAIILVGMEG 272 Query: 298 DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKIN 357 +L + + G+ +G E V +L K + + +P + IN Sbjct: 273 KRVSLEAFDT-AVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIK------VPLDDIN 325 Query: 358 EGFDLLRSGKS-IRTVLT 374 + F L G+ R V+T Sbjct: 326 KAFTNLDEGRVDGRQVIT 343 >6DKH-A nrPDB Length = 346 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 79/327 (24%), Positives = 128/327 (39%), Gaps = 34/327 (10%) Query: 38 RIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL 93 +++ GIC SD H GN + P++LGHE G V + + + G V Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAIN 91 Query: 94 FTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVV 153 + CG C+ C N C RF S H G F++Y +V Sbjct: 92 PSKPCGHCKYCIEHNENQCT--------------DMRFFGSAMYFPHVDG--GFTRYKMV 135 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 + + A + EKV + +A + ++ G + G+G +G +V K Sbjct: 136 ETSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVK 193 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 GAA I+ D++ + KE+GA +NPQ+ + K G D SFEV G Sbjct: 194 TLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEK----GYFDVSFEVSGHP 249 Query: 274 DTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLV 333 ++ L A G V VG+ ++ PM+ L G+ ++ G F+ V Sbjct: 250 SSVNTCLEVT-RARGVMVQVGM---GGAMAEFPMMTLIGKEI--SLRGSFRFTSEFNTAV 303 Query: 334 ADFMAKKFSLDALITNILPFEKINEGF 360 + + L++ PF + E Sbjct: 304 SWLANGVINPLPLLSAEYPFTDLEEAL 330 >5FI5-A nrPDB Length = 357 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 78/345 (22%), Positives = 130/345 (37%), Gaps = 39/345 (11%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSGNLV-TPLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 H+V++K++ G C+ D + T P +LGHE G V VG V K GDKV Sbjct: 41 GEHDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVG 100 Query: 91 IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQY 150 + CGKC +C N NYC + + S Sbjct: 101 VASIIETCGKCEMCTNEVENYCPEAGSIDS----------------------NYGACSNI 138 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 V++EN V + PL+ + C T Y + PG + GLGG+G + Sbjct: 139 AVINENFVIRWPENLPLDSGVPLLCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALR 198 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 KA GA + K K ++ GA + + ++ + G +D + I Sbjct: 199 FAKAFGAKVTVISSSLKKKREAFEKFGADSFLVSSNPEE------MQGAAGTLDGIIDTI 252 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVP 330 ++ LL + G +I+G P + P LL+ G+ + G K + Sbjct: 253 PGNHSLE-PLLALLKPLGKLIILGAPEMPFEVPA-PSLLMGGKVMAASTAGSMKEIQE-- 308 Query: 331 KLVADFMAKKFSLDALITNILPFEKINEGFDLLR-SGKSIRTVLT 374 + +F A+ + + ++ + +N + L S R V+ Sbjct: 309 --MIEFAAEHNIVADV--EVISIDYVNTAMERLDNSDVRYRFVID 349 >4ILK-A nrPDB Length = 359 Score = 208 bits (530), Expect = 3e-54, Method: Composition-based stats. Identities = 91/368 (24%), Positives = 145/368 (39%), Gaps = 38/368 (10%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG-NLVTPLPVILGHEAA 71 ++L E SI E E+ P A EVR+K+ AGIC SD H+ G N P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G++++VGEGV + + G++V CG C C + N C + G DG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADG---- 135 Query: 132 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVT 191 FS+Y VV KI A + +I T + + T Sbjct: 136 --------------GFSEYAVVPAKNAWKIPEAVADQYAVMIE--PFTIAANVTGHGQPT 179 Query: 192 PGSTCAVFGLGGVGLSVVMGCK-AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 T V+G G +GL++V K +I D ++ KAKE GA IN + + P Sbjct: 180 ENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--NSQTP 237 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 + E E + + ++ A V++G + + + Sbjct: 238 LGESFAEKGIK-PTLIIDAACHPSILKEAVTLASPAA-RIVLMGFSSEPSEV------IQ 289 Query: 311 TGRT-WKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDL--LRSGK 367 G T + +IF + P ++ + LIT+ F+ + + L L Sbjct: 290 QGITGKELSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFELDQKH 349 Query: 368 SIRTVLTF 375 + +LTF Sbjct: 350 CCKVLLTF 357 >6FG0-A nrPDB Length = 352 Score = 208 bits (528), Expect = 5e-54, Method: Composition-based stats. Identities = 87/362 (24%), Positives = 145/362 (40%), Gaps = 34/362 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS---GNLVTPLPVILG 67 KA E+ + ++ P E+ +K+ AAG+C SD V+ LP+ LG Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDG 127 HE G V +GEGVT GD V CG C C NYC Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYC--------------- 106 Query: 128 TRRFTCSGKPIHHFVGVSTFSQYTVVD-ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 R G + + ++Y +VD + I P+ + T Y + + Sbjct: 107 -TRAADLGITPPGYGSPGSMAEYMIVDSARHLVPIGDLDPV-AAAPLTDAGLTPYHAISR 164 Query: 187 -VAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + + PGST V G+GG+G + +A AAR+IAVD++ D+ A A+E+GA + Sbjct: 165 VLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKSG 224 Query: 246 DYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304 + ++E+T G G F+ +G T+ + G +VG+ + + Sbjct: 225 ---AGAADAIRELTGGQGATAVFDFVGAQSTIDTA-QQVVAVDGHISVVGIHAGAHA-KV 279 Query: 305 NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364 ++ G + +G + ++VA A + + T ++ + LR Sbjct: 280 GFWMIPFGASVVTPYWGTRS---ELMEVVALARAGRLDIH---TETFTLDEGPAAYRRLR 333 Query: 365 SG 366 G Sbjct: 334 EG 335 >3M6I-A nrPDB Length = 363 Score = 207 bits (526), Expect = 8e-54, Method: Composition-based stats. Identities = 73/363 (20%), Positives = 142/363 (39%), Gaps = 37/363 (10%) Query: 15 LWELKKPFSIEEVEVAPP-KAHEVRIKMVAAGICRSDEHVVSGNLVTPLPV----ILGHE 69 LW + S+E V+ K EV + + + GIC SD H + P+ V +LGHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTR 129 +AG V +V V ++K GD+V C C C N C + D + + R Sbjct: 80 SAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTP-PVPGLLR 138 Query: 130 RFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 R+ H +G ++ +++ +VA + ++ A Sbjct: 139 RYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQRAG 176 Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL---GATECINPQD 246 V G + G G +GL ++ KAAGA ++ DI++ + AKE+ T + Sbjct: 177 VRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEICPEVVTHKVERLS 236 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 ++ +++++ + E G ++ A++ + G ++GV + + Sbjct: 237 AEESAKKIVESFGGIEPAVALECTGVESSIAAAIWAV-KFGGKVFVIGVGKNEIQIP--- 292 Query: 307 MLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 + + + ++ + P+ + L L+T+ P E + F+ Sbjct: 293 --FMRASVREVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFETASDP 350 Query: 367 KSI 369 K+ Sbjct: 351 KTG 353 >4UEJ-A nrPDB Length = 346 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 87/369 (23%), Positives = 143/369 (38%), Gaps = 33/369 (8%) Query: 13 AVLWELKKPFSIEEVEVAPPK-AHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAA 71 +V+ + + E + K EVR+K+ ++G+C SD + N P+ LGHE + Sbjct: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G +++VG GV + PGD V + C C C + C K D G+ +DG Sbjct: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDG---- 115 Query: 132 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVT 191 F++Y VV V + P+E I T A +A+ Sbjct: 116 --------------GFAEYIVVKRKNVFALPTDMPIEDGAFIE--PITVGLHAFHLAQGC 159 Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP- 250 + G G +GL + A GA + A+DI+ +K A AK GA + N + P Sbjct: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS--INPML 308 +Q VL+E+ E G T+ ++ +VG +L+ + Sbjct: 220 MQSVLRELRFN--QLILETAGVPQTVELAVE-IAGPHAQLALVGTLHQDLHLTSATFGKI 276 Query: 309 LLTGRTWKGAIFGGFKSK--ESVPKLVADFMAKKFSLDALITNILPFEKINEGF-DLLRS 365 L T G+ + +K SL+ LI + FE + D+ R+ Sbjct: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 Query: 366 GKSIRTVLT 374 + +L Sbjct: 337 AMPGKVLLI 345 >3IP1-A nrPDB Length = 404 Score = 206 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 83/384 (21%), Positives = 140/384 (36%), Gaps = 47/384 (12%) Query: 15 LWELKKPFSIEEVEVAPP-KAHEVRIKMVAAGICRSDEHVVSGN--------LVTPLPVI 65 +W + +EEV K E+ IK+ A GIC SD H+ + +T PV Sbjct: 36 VWRYPE-VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVT 94 Query: 66 LGHEAAGIVESVGEGV------TTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGN 119 LGHE +G+V G + G+ V CG CR C N+C + Sbjct: 95 LGHEFSGVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLN--- 151 Query: 120 PRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEK------VCLI 173 F F++Y VD + + + + Sbjct: 152 ------------------ELGFNVDGAFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSL 193 Query: 174 GCGFSTGYGSA-VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAK 232 S Y + V+ + PG + G G +GL+ V K AGA+++I + ++ + Sbjct: 194 VEPTSVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNL 253 Query: 233 AKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL-LCCHEACGTSV 291 AKELGA I+P + ++ VL G E G + + A G + Sbjct: 254 AKELGADHVIDPTK-ENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINA 312 Query: 292 IVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNIL 351 V + + + R + G + P++++ MA + +I+ + Sbjct: 313 TVAIVARADAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTV 371 Query: 352 PFEKINEGFDLLRSGKSIRTVLTF 375 E+I E L++ KS+ V Sbjct: 372 SMEEIPEYIKRLQTDKSLVKVTML 395 >2OUI-A nrPDB Length = 360 Score = 202 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 87/350 (24%), Positives = 138/350 (39%), Gaps = 32/350 (9%) Query: 24 IEEVEVAPPKAHEVRIKMVAAGICRSDEH-VVSGNLVTPLPVILGHEAAGIVESVGEGVT 82 E ++ + ++ +A C SD H V +G + +ILGHEA G + VG V Sbjct: 14 WIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVK 73 Query: 83 TVKPGDKVI-PLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 +K GDKVI P TP G+ + + G +DG Sbjct: 74 RLKVGDKVIVPAITPDWGEEESQR-GYPMHSGGMLGGWKFSNFKDGV------------- 119 Query: 142 VGVSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF 199 FS+ V+E +A + E ++ +TG+ A ++A + G T V Sbjct: 120 -----FSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDTVCVI 173 Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G+G VGL V G GA RI AV K A E GAT+ IN ++ ++++LK Sbjct: 174 GIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN-GDIVEQILKATD 232 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL---LTGRTWK 316 GVD G + T A + + V + N+ I + + Sbjct: 233 GKGVDKVVIAGGDVHT-FAQAVKMIKPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIH 291 Query: 317 GAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKINEGFDLLRS 365 G + G + + KL + K LIT+ EK+ + L+++ Sbjct: 292 GGLTPGGRVRME--KLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKN 339 >5VKT-A nrPDB Length = 362 Score = 200 bits (508), Expect = 1e-51, Method: Composition-based stats. Identities = 81/346 (23%), Positives = 126/346 (36%), Gaps = 31/346 (8%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSGNLVT-PLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 +V IK++ GIC +D HV+ PV+ GHE G+V VG GVT K GD V Sbjct: 33 GDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGDTVG 92 Query: 91 IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQY 150 + F C C C NYC D H FS Sbjct: 93 VGYFVDSCRTCESCSTGHENYCP------------DLVLTSNGVDHHHHGATTKGGFSDV 140 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 VV ++ V ++ + PL+ + C T Y + A PG V GLGG+G V Sbjct: 141 LVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPGKHLGVVGLGGLGHMAVK 200 Query: 211 GCKAAGAARIIAVDINKDKFAKAK-ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV 269 KA G + + + K +A LGA + D + +D + Sbjct: 201 FAKAFGM-TVTVISSSPGKRDEALGRLGADAFLVSHDAAQMKAAAAT------LDGIIDT 253 Query: 270 IGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESV 329 + ++ LL + G V+VG P L ++ G+ G G + Sbjct: 254 VSAGHQIV-PLLALLKPMGQMVVVGAPSTPLELPAYAIIT-GGKRVAGNGVGSVADCQ-- 309 Query: 330 PKLVADFMAKKFSLDALITNILPFEKINEGFDLL-RSGKSIRTVLT 374 + DF + + ++ + +N + L ++ R V+ Sbjct: 310 --AMLDFAGEHGVTADI--EVVQMDYVNTAIERLEKNDVRYRFVID 351 >5H83-A nrPDB Length = 360 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 77/348 (22%), Positives = 131/348 (37%), Gaps = 41/348 (11%) Query: 33 KAHEVRIKMVAAGICRSDEHVVSGNLV-TPLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 ++V+ K++ G C D + + T P ++GHE G+V +G V K GDKV Sbjct: 38 GENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVG 97 Query: 91 IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQY 150 + F C KC +C N N C K + + H Sbjct: 98 VGGFVGACEKCEMCVNGVENNCSKVESTDG------------------HFGNNFGGCCNI 139 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 VV+E PL + C T Y + PG + GLGG+G + Sbjct: 140 MVVNEKYAVVWPENLPLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAGLGGLGHLAIR 199 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECI---NPQDYKKPIQEVLKEMTDGGVDFSF 267 KA GA + K K ++ G + NP++ + G +D Sbjct: 200 FAKAFGAKVTLISSSVKKKREALEKFGVDSFLLNSNPEEMQGAY---------GTLDGII 250 Query: 268 EVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKE 327 + + +++ L + G +I+GVP + + P LL+ G+ G+ G K + Sbjct: 251 DTMPVAHSIV-PFLALLKPLGKLIILGVPEEPFEVPA-PALLMGGKLIAGSAAGSMKETQ 308 Query: 328 SVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR-SGKSIRTVLT 374 + DF AK + + ++P + +N + ++ S R V+ Sbjct: 309 E----MIDFAAKHNIVADV--EVIPIDYLNTAMERIKNSDVKYRFVID 350 >1YB5-A nrPDB Length = 351 Score = 195 bits (495), Expect = 3e-50, Method: Composition-based stats. Identities = 75/385 (19%), Positives = 143/385 (37%), Gaps = 66/385 (17%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIE---EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN 57 M+T K+++ A ++E P ++ ++ V PK H+V IK+ A G+ + ++ SG Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 LVTP--LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKN 115 LP G + AG++E+VG Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVG------------------------------------- 103 Query: 116 DLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 D F + +++Y + ++ V K+ ++ IG Sbjct: 104 ----------DNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGAAIGI 153 Query: 176 GFSTGYGSAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAK 234 + T Y + + A V G + V G GGVGL+ +A G +I+ ++ Sbjct: 154 PYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVL 212 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + GA E N ++ I ++ K + + G+D E++ ++ L G ++VG Sbjct: 213 QNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKD--LSLLSHGGRVIVVG 269 Query: 295 VPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAK--KFSLDALITNILP 352 + INP + + + +KE + A A L +I + P Sbjct: 270 ---SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYP 326 Query: 353 FEKINEGFDLLRSGK--SIRTVLTF 375 EK+ E + + G + + +L Sbjct: 327 LEKVAEAHENIIHGSGATGKMILLL 351 >3UOG-A nrPDB Length = 363 Score = 191 bits (485), Expect = 4e-49, Method: Composition-based stats. Identities = 80/365 (21%), Positives = 133/365 (36%), Gaps = 41/365 (11%) Query: 17 ELKKPFSIE--EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL--PVILGHEAAG 72 E P ++ E V H++ ++ +A + D+ V+ + L P + + +G Sbjct: 34 ETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSG 93 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 +VE+VG+ VT +PGD+VI F P DG R T Sbjct: 94 VVEAVGKSVTRFRPGDRVISTFAPGW--------------------------LDGLRPGT 127 Query: 133 CSGKPIHHFVG--VSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKV 190 G S+Y V+ E + + + C T + + V+ + Sbjct: 128 GRTPAYETLGGAHPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHL 187 Query: 191 TPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 G V G GGV L + KA GA +I +++K +A LGA IN + + Sbjct: 188 RAGDRVVVQGTGGVALFGLQIAKATGA-EVIVTSSSREKLDRAFALGADHGIN-RLEEDW 245 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 ++ V D G D E+ G + L G ++GV + LLL Sbjct: 246 VERVYALTGDRGADHILEIAGGAG--LGQSLKAVAPDGRISVIGVLEGFEVSGPVGPLLL 303 Query: 311 TGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIR 370 +G G ++ E + V + L +I F ++ E L G + Sbjct: 304 KSPVVQGISVGHRRALEDLVGAVD-----RLGLKPVIDMRYKFTEVPEALAHLDRGPFGK 358 Query: 371 TVLTF 375 V+ F Sbjct: 359 VVIEF 363 >2DPH-A nrPDB Length = 398 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 93/399 (23%), Positives = 151/399 (37%), Gaps = 50/399 (12%) Query: 13 AVLWELKKPFSIEEVEVAPPK------AHEVRIKMVAAGICRSDEHVVSGNLVTPLPVIL 66 +V++ + +E V + H V +K+V+ IC SD+H+ G + P +L Sbjct: 5 SVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPKGHVL 64 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 GHE G V G V + GD V F CG+CR CK S+ C N + Sbjct: 65 GHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADLGAF 124 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKV---CLIGCGFSTGYGS 183 G SG + + ++ Y + + D +EK+ LI TG+ Sbjct: 125 GFDLKGWSGGQAEYVLVP--YADYML-----LKFGDKEQAMEKIKDLTLISDILPTGFHG 177 Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG--ATEC 241 V A V PGS + G G VG G + GAA +I D N ++ + G + Sbjct: 178 CVS-AGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFETIDL 236 Query: 242 INPQDYKKPIQEVL-KEMTDGGVD-FSFEVIG--------RLDTMMASLLCCHEACGTS- 290 N + I ++L K D GVD FE G + + SL A G Sbjct: 237 RNSAPLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAGGAIG 296 Query: 291 ---VIVGVPPDSQNLSINP--MLLLTGRTWKGAIFG----------GFKSKESVPKLVAD 335 + VG PD N + L G+ W +I E++ Sbjct: 297 IPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNRHLTEAILWDQMP 356 Query: 336 FMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLT 374 +++K +++ ++ ++ +G+ G + V+ Sbjct: 357 YLSKVMNIE-----VITLDQAPDGYAKFDKGSPAKFVID 390 >3WLE-A nrPDB Length = 341 Score = 182 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 90/353 (25%), Positives = 149/353 (42%), Gaps = 46/353 (13%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVK 85 ++ V PKA ++ +K+ A G+C SD HV+ L ++GHE AG V +VG+ V K Sbjct: 28 DLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINYK 87 Query: 86 PGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVS 145 GD+V + CG C+ C+ N C KN G+ G DG Sbjct: 88 VGDRVACVGPNGCGGCKYCRGAIDNVC-KNAFGDWFGLGYDG------------------ 128 Query: 146 TFSQYTVV-DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGV 204 + QY +V +++I + T Y A+K+A+V+P S + G GG+ Sbjct: 129 GYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYH-AIKMAQVSPTSNILLIGAGGL 187 Query: 205 GLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G + + KA GA ++ +D K+ +AK+LGA + E L E G Sbjct: 188 GGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGAD----------AVYETLPESISPG-- 234 Query: 265 FSFEVIGRLDTMMASLLCCHE---ACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFG 321 SF ++ A+ C + G + VG+ + + ++ L L G+ +G Sbjct: 235 -SFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGD-LALREIRILGSFWG 292 Query: 322 GFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK-SIRTVL 373 + V KLV++ K + +++ E + LR+ R V Sbjct: 293 TTNDLDDVLKLVSEGKVKP------VVRSAKLKELPEYIEKLRNNAYEGRVVF 339 >4JLW-A nrPDB Length = 399 Score = 182 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 88/393 (22%), Positives = 156/393 (39%), Gaps = 40/393 (10%) Query: 14 VLWELKKPFSIEEVEVAPPKA-------HEVRIKMVAAGICRSDEHVVSGNLVTPLPVIL 66 V++ ++ + + H V +++V+ IC SD+H+V G P ++L Sbjct: 7 VVYLGPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGLVL 66 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 GHE G V +G GV T+K GD V F CG CR CK + CL + G Sbjct: 67 GHEITGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPARAGGAYGY 126 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVD-ENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 G+ + V + F+ + + E A+ KI + L + TGY AV Sbjct: 127 VDMGGWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDI------LPTGYHGAV 180 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 A V PGST + G G VGL+ + GAA +I D+N + A AK+ G E + Sbjct: 181 -TAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQG-FEIADLS 238 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIG--------------RLDTMMASLLCCHEACGTSV 291 +++ + + VD + + +G T++ SL+ G Sbjct: 239 KDTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPATVLNSLMGITRVAGKIG 298 Query: 292 IVGVPPDSQNLSIN------PMLLLTGRTWKGA---IFGGFKSKESVPKLVADFMAKKFS 342 I G+ +++ + + G W + G + +L+ M + Sbjct: 299 IPGLYVTEDPGAVDAAAKHGALSIRFGLGWAKSHSFHTGQTPVMKYNRQLMQAIMWDRIK 358 Query: 343 LDALI-TNILPFEKINEGFDLLRSGKSIRTVLT 374 + ++ ++ + +G+ +G + V+ Sbjct: 359 IADIVGVEVITLDDAPKGYGEFDAGVPKKFVID 391 >1Q1N-A nrPDB Length = 360 Score = 180 bits (456), Expect = 9e-46, Method: Composition-based stats. Identities = 80/357 (22%), Positives = 136/357 (38%), Gaps = 37/357 (10%) Query: 16 WELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT-PLPVILGHEAAGIV 74 W+ K + H++ IK+ A G+C SD H +G+ +P+++GHE G V Sbjct: 18 WKNPKKTKYDPKPF---YDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKV 74 Query: 75 ESVGEGV-TTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 +G + +K G +V + C +C CKN YC K + +DG Sbjct: 75 VKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKF-VTTYSQPYEDG----- 128 Query: 133 CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP 192 +V ++ Y V E+ V I P + CG T Y V+ P Sbjct: 129 --------YVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNGC-GP 179 Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + GLGG+G + KA GA + + K A ++GA I + + Sbjct: 180 GKKVGIVGLGGIGSMGTLISKAMGA-ETYVISRSSRKREDAMKMGADHYIATLEEGDWGE 238 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLL-CCHEACGTSVIVGVPPDSQNLSINPMLLLT 311 + D L + +++ + G V + +P + LS+ P L Sbjct: 239 KYF-----DTFDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYG-LK 292 Query: 312 GRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEK--INEGFDLLRSG 366 + + G K + KLV++ K + LP + ++E F+ + G Sbjct: 293 AVSISYSALGSIKELNQLLKLVSEKDIK------IWVETLPVGEAGVHEAFERMEKG 343 >1KOL-A nrPDB Length = 398 Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 87/392 (22%), Positives = 154/392 (39%), Gaps = 38/392 (9%) Query: 14 VLWELKKPFSIEEVEVAPPKA-------HEVRIKMVAAGICRSDEHVVSGNLVTPLPVIL 66 V++ +++++ + H V +K+V+ IC SD+H+V G + ++L Sbjct: 6 VVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGLVL 65 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 GHE G V G V ++ GD V F CG+CR CK + CL + G Sbjct: 66 GHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARAGGAYGY 125 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVD-ENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 G+ + V + F+ + D + A+ KI + L + TGY AV Sbjct: 126 VDMGDWTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDI------LPTGYHGAV 179 Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG---ATECI 242 A V PGST V G G VGL+ + GAA +I D+N + A AK G A + Sbjct: 180 -TAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEIADLSL 238 Query: 243 NPQDYKKPIQEVLKEMTDGGVD-FSFEVIGR---------LDTMMASLLCCHEACGTSVI 292 + +++ + + D VD FE G T++ SL+ G I Sbjct: 239 DTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGKIGI 298 Query: 293 VGVPPDSQNLSINPMLLLTGRTWKGAI---------FGGFKSKESVPKLVADFMAKKFSL 343 G+ +++ + + + + G + L+ M + ++ Sbjct: 299 PGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDRINI 358 Query: 344 DALI-TNILPFEKINEGFDLLRSGKSIRTVLT 374 ++ ++ + G+ +G + V+ Sbjct: 359 AEVVGVQVISLDDAPRGYGEFDAGVPKKFVID 390 >3QWB-A nrPDB Length = 334 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 83/363 (22%), Positives = 126/363 (34%), Gaps = 66/363 (18%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGV 81 E+ V E+ IK G+ + + G P +LG EA+G V + G+GV Sbjct: 23 IKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGV 82 Query: 82 TTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 T + GD+V + Sbjct: 83 TNFEVGDQVA-------------------------------------------------Y 93 Query: 142 VGVSTFSQY-TVVDENAVAKIDAASPLEKVCLIGCGFS---TGYGSAVKVAKVTPGSTCA 197 + STF+QY + + V K+ + E++ L G T + V G Sbjct: 94 ISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVL 153 Query: 198 VFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 +F GGVGL + K GA IAV +K AKE GA IN + +++VLK Sbjct: 154 LFAAAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLK 211 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS-QNLSINPMLLLTGRTW 315 GVD SF+ +G+ DT SL + G V G SI + Sbjct: 212 FTNGKGVDASFDSVGK-DTFEISL-AALKRKGVFVSFGNASGLIPPFSITRLSPKNITLV 269 Query: 316 KGAIFGGFKSKESVPKLVADFM----AKKFSLDALITNILPFEKINEGFDLLRSGKS-IR 370 + ++G E +F +KK ++ I P + S K+ + Sbjct: 270 RPQLYGYIADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESRKTVGK 327 Query: 371 TVL 373 VL Sbjct: 328 LVL 330 >6C49-A nrPDB Length = 350 Score = 168 bits (426), Expect = 3e-42, Method: Composition-based stats. Identities = 70/368 (19%), Positives = 131/368 (35%), Gaps = 39/368 (10%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL-VTPLPVILG 67 +A + + + + + H+V +K+ G+C SD V++ T PV+ G Sbjct: 13 TIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAG 72 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 HE G + ++G ++ G +V I C C C + C ++ G Sbjct: 73 HEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVGH--- 129 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 F+ + E + CG T + +K Sbjct: 130 -----------------AGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLK 172 Query: 187 VAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 K+ V G+GG+G + KA G I A N DK + K +GA +N +D Sbjct: 173 H-KIQATHHVGVIGIGGLGHIAIKLLKAWG-CEITAFSSNPDKTEELKAMGADHVVNSRD 230 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 + + G D + + + + G+ +G+ + +S+ Sbjct: 231 TEAVKAQ------KGKFDLLLSTV-NVTLNWRAFISTLAPNGSLHFLGLTLEPVPVSVGS 283 Query: 307 MLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSG 366 L+ ++ G+ G + + K A + + I + P ++NE + L SG Sbjct: 284 -LIDGAKSVTGSPTGSPAALRQLLKF-----AARKKIAPQI-ELFPMSQLNEAIERLHSG 336 Query: 367 KS-IRTVL 373 ++ R VL Sbjct: 337 QARYRIVL 344 >1WLY-A nrPDB Length = 333 Score = 160 bits (405), Expect = 8e-40, Method: Composition-based stats. Identities = 84/384 (21%), Positives = 144/384 (37%), Gaps = 77/384 (20%) Query: 12 AAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL-----PV 64 AAV+ + P F EEV+V P +VR++ A G+ D + +G + PL P+ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAG-IPHPLVVGEPPI 62 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTL 124 ++G EAA +VE VG GVT G+ R+C CL Sbjct: 63 VVGFEAAAVVEEVGPGVTDFTVGE-------------RVCT------CLP---------- 93 Query: 125 QDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCG--FSTGYG 182 + +SQ + + K+ L+ V L G T Sbjct: 94 ------------------PLGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQY 135 Query: 183 SAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 + KV PG + GG+G +V + GA +I ++K A++LG Sbjct: 136 LLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGA-TVIGTVSTEEKAETARKLGCHHT 194 Query: 242 INPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 IN + EV++E+T G GVD ++ IG+ DT+ SL C G G Sbjct: 195 INYS--TQDFAEVVREITGGKGVDVVYDSIGK-DTLQKSLD-CLRPRGMCAAYGHASGVA 250 Query: 301 NLSINPMLLLTGRTWKGAIFGG-------FKSKESVPKLVADF--MAKKFSLDALITNIL 351 + P+ ++ +G++F ++ + + K L + + Sbjct: 251 D----PIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFDAVKAGVLHSSVAKTF 306 Query: 352 PFEKINEGFDLLRSGKSIRTVLTF 375 P + + ++I +++ Sbjct: 307 PLREAAAAHKYMGGRQTIGSIVLL 330 >3B70-A nrPDB Length = 371 Score = 154 bits (388), Expect = 8e-38, Method: Composition-based stats. Identities = 70/370 (18%), Positives = 118/370 (31%), Gaps = 72/370 (19%) Query: 23 SIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVT 82 +V +++ A I SD + G TP LG + AG V +VG VT Sbjct: 25 VWNAAPCPMLPRDQVYVRVEAVAINPSDTKMR-GQFATPW-AFLGTDYAGTVVAVGSDVT 82 Query: 83 TVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFV 142 ++ GD+V C Sbjct: 83 HIQVGDRVYGAQNEMC----------------------------------------PRTP 102 Query: 143 GVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV---------AKVTPG 193 FSQYTV AKI E+ + G ST G A+K+ A P Sbjct: 103 DQGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTA-GLAMKLLGLPLPSPSADQPPT 161 Query: 194 ST----CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 + V+G G + V + I + F AK GA E + + Sbjct: 162 HSKPVYVLVYG-GSTATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVFDYRAPN- 219 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD--------SQN 301 + + ++ T + ++ + I +++ A G V + P+ + + Sbjct: 220 -LAQTIRTYTKNNLRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTD 278 Query: 302 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADF--MAKKFSLDALITNILPFEKINEG 359 ++ P + G TW G E + D +A + D + + P + G Sbjct: 279 WTLGPTIFGEGSTWPAPY--GRPGSEEERQFGEDLWRIAGQLVEDGRLVH-HPLRVVQGG 335 Query: 360 FDLLRSGKSI 369 FD ++ G + Sbjct: 336 FDHIKQGMEL 345 >2VCY-A nrPDB Length = 344 Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats. Identities = 80/383 (20%), Positives = 142/383 (37%), Gaps = 67/383 (17%) Query: 9 KCKAAVLWELKKP---FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV--TPLP 63 + +A V P ++ +E+A + +VR+KM+AA I SD +++ GN LP Sbjct: 13 RVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELP 72 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGT 123 + G+E V +VG VT +KPGD VIP Sbjct: 73 AVGGNEGVAQVVAVGSNVTGLKPGDWVIPANA---------------------------- 104 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 G+ T+ V E A+ ++ + PL+ +G T Y Sbjct: 105 -------------------GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRM 145 Query: 184 AVKVAKVTPGSTCA-VFGLGGVGLSVVMGCKAAGAARIIAVDINKD--KF-AKAKELGAT 239 + ++ PG + GVG +V+ A G I V D K + K LGA Sbjct: 146 LMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAE 205 Query: 240 ECINPQDYKKP-IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298 I ++ ++P ++ K+M + +G + LL GT V G Sbjct: 206 HVITEEELRRPEMKNFFKDMPQP--RLALNCVGGKSSTE--LLRQLARGGTMVTYGGMAK 261 Query: 299 SQNLSINPMLLLTGRTWKGAIFGGFK---SKESVPKLVADF--MAKKFSLDALITNILPF 353 ++ +L+ +G +K S + +L+ + ++ L A + +P Sbjct: 262 QPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPL 321 Query: 354 EKINEGFDL-LRSGKSIRTVLTF 375 + + ++ S + +LT Sbjct: 322 QDYQSALEASMKPFISSKQILTM 344 >2CF5-A nrPDB Length = 357 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 80/363 (22%), Positives = 142/363 (39%), Gaps = 31/363 (8%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV-TPLPVILGHEAAGI 73 + S + +V I+++ GIC +D H +L + P++ GHE G Sbjct: 15 ARDPSGILSPYTYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGE 74 Query: 74 VESVGEGVTTVKPGD-KVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 V VG V+ GD + CG C C+ YC K + ++ Sbjct: 75 VVEVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPK--------------KIWS 120 Query: 133 CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP 192 + I+ F++ TVV + V KI +E+ + C T Y P Sbjct: 121 YNDVYINGQPTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQP 180 Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + GLGGVG V KA G + NK + ++LGA + + D Q Sbjct: 181 GLRGGILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSD-----Q 235 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTG 312 + E+ D +D+ + + + L + G +++GV + + P+L+L Sbjct: 236 AKMSELADS-LDYVIDTVPVHHALEPYL-SLLKLDGKLILMGVINNPLQF-LTPLLMLGR 292 Query: 313 RTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLL-RSGKSIRT 371 + G+ G K E + + K+ L ++I ++ + +N F+ L ++ R Sbjct: 293 KVITGSFIGSMKETEEMLEFC-----KEKGLSSII-EVVKMDYVNTAFERLEKNDVRYRF 346 Query: 372 VLT 374 V+ Sbjct: 347 VVD 349 >1QOR-A nrPDB Length = 327 Score = 152 bits (383), Expect = 3e-37, Method: Composition-based stats. Identities = 84/362 (23%), Positives = 132/362 (36%), Gaps = 63/362 (17%) Query: 15 LWELKKPFSIEEVEVAP--PKAHEVRIKMVAAGICRSDEHVVSGNLVTP-LPVILGHEAA 71 + P ++ VE P P +E++++ A GI D ++ SG P LP LG EAA Sbjct: 7 FHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAA 66 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 131 GIV VG GV +K GD+V+ Sbjct: 67 GIVSKVGSGVKHIKAGDRVV---------------------------------------- 86 Query: 132 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVT 191 + + +S + + A + AA E+ T Y K ++ Sbjct: 87 -------YAQSALGAYSSVHNIIADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIK 139 Query: 192 PGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 P GGVGL KA GA ++I K A + GA + IN ++ + Sbjct: 140 PDEQFLFHAAAGGVGLIACQWAKALGA-KLIGTVGTAQKAQSALKAGAWQVINYRE--ED 196 Query: 251 IQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN------LS 303 + E LKE+T G V ++ +GR DT SL C G V G + L+ Sbjct: 197 LVERLKEITGGKKVRVVYDSVGR-DTWERSLDCLQRR-GLMVSFGNSSGAVTGVNLGILN 254 Query: 304 INPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLL 363 L +T + +G I + E+ +L + + +D P + ++L Sbjct: 255 QKGSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEIL 314 Query: 364 RS 365 S Sbjct: 315 ES 316 >4RVS-A nrPDB Length = 329 Score = 145 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 70/377 (18%), Positives = 123/377 (32%), Gaps = 65/377 (17%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAH--EVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHE 69 A + E P + V+ P+ E+ IK A G+ D + SG LP ++G E Sbjct: 4 AIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSE 63 Query: 70 AAGIVESVGEGVTT----VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 G VE+VG GVT + GD+V+ Sbjct: 64 VCGTVEAVGPGVTAADTAISVGDRVVSA-------------------------------- 91 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 ++++ + AK+ E T + Sbjct: 92 ----------------SANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLK 135 Query: 186 KVAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 V V G T V G GGVGL + G R+I +K +K+ GA ++ Sbjct: 136 SVYPVKRGDTVLVHAGAGGVGLILTQWATHLGV-RVITTVSTAEKAKLSKDAGADVVLDY 194 Query: 245 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 + ++E+T G GV ++ +G T + L GT + G Sbjct: 195 PEDAWQFAGRVRELTGGTGVQAVYDGVGA--TTFDASLASLAVRGTLALFGAASGPVP-P 251 Query: 304 INPMLLLTGRTW---KGAIFGGFKSKESVPKLVADFMAKKFS--LDALITNILPFEKINE 358 ++P L + + ++F ++ E A+ + + + P Sbjct: 252 VDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGNEAITVAVGGRYPLADALR 311 Query: 359 GFDLLRSGKSIRTVLTF 375 L + K++ +V+ Sbjct: 312 AHQDLEARKTVGSVVLL 328 >3JYN-A nrPDB Length = 325 Score = 140 bits (353), Expect = 9e-34, Method: Composition-based stats. Identities = 78/368 (21%), Positives = 130/368 (35%), Gaps = 66/368 (17%) Query: 19 KKPFSIEEVEVAP--PKAHEVRIKMVAAGICRSDEHVVSGNLVTP-LPVILGHEAAGIVE 75 P +E V+ P P V ++ A G+ D + SG P LP LG E AG+VE Sbjct: 11 GGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVE 70 Query: 76 SVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSG 135 +VG+ VT RF Sbjct: 71 AVGDEVT-----------------------------------------------RFKVGD 83 Query: 136 KPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGST 195 + + + +S+ V+ E + K+ + E+ + T + +V PG Sbjct: 84 RVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGEI 143 Query: 196 CAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 GGVG KA GA ++I + +K A AK LGA E I+ + + + Sbjct: 144 ILFHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDYS--HEDVAKR 200 Query: 255 LKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG---VPPDSQNLSINPML-- 308 + E+TDG ++ +G DT + SL G V G P NL I Sbjct: 201 VLELTDGKKCPVVYDGVG-QDTWLTSLDSVAPR-GLVVSFGNASGPVSGVNLGILAQKDS 258 Query: 309 LLTGRTWKGAIFGGFKSKESV-PKLVADFMAKKFSLDALITNILPFEKINEG-FDLLRSG 366 + R G+ ++ +++ +L + K +D + + + +L Sbjct: 259 VYVTRPTLGSYANNAQNLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELSARR 316 Query: 367 KSIRTVLT 374 + T+L Sbjct: 317 TTGSTILI 324 >2OBY-A nrPDB Length = 338 Score = 130 bits (327), Expect = 1e-30, Method: Composition-based stats. Identities = 72/370 (19%), Positives = 123/370 (33%), Gaps = 64/370 (17%) Query: 19 KKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPV--ILGHEAAGIVES 76 + ++EV P EV +K+ A+ + R+D G P ILG EA+G V Sbjct: 18 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 77 Query: 77 VGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGK 136 +G G C+ G Sbjct: 78 LGPG-----------------------CQGH------------------------WKIGD 90 Query: 137 PIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTC 196 + +QY V E + I L + I + T + V V G Sbjct: 91 TAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYV 150 Query: 197 AVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 + GL GVG + + + AGA + ++ K A++LGA N + + + L Sbjct: 151 LIHAGLSGVGTAAIQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKK-EDFSEATL 208 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ-NLSINPMLLLTGRT 314 K GV+ + IG + + C G V+ G+ N + LL + Sbjct: 209 KFTKGAGVNLILDCIGG--SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGS 266 Query: 315 WKGAIFGGF--KSKESVPKLVADFMAKKFSLD------ALITNILPFEKINEGFDLLRSG 366 ++ K K+ + + + FS + ++ I P +I E + + Sbjct: 267 LITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEAN 326 Query: 367 KSI-RTVLTF 375 K+I + VL Sbjct: 327 KNIGKIVLEL 336 >4J6F-A nrPDB Length = 382 Score = 129 bits (325), Expect = 1e-30, Method: Composition-based stats. Identities = 63/385 (16%), Positives = 119/385 (30%), Gaps = 62/385 (16%) Query: 12 AAVLWELKKPFSI---EEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT-------- 60 A +L + +V V P A EV IK+ A G+ +D V G T Sbjct: 36 AVLLTGHGGLEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVS 95 Query: 61 ---------PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNY 111 P I G + G + +VGEGV + G++V+ F+ Sbjct: 96 TWRRHGNTLTFPRIQGTDTVGHIVAVGEGVDRARIGERVMVDFSI--------------- 140 Query: 112 CLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVC 171 + + +++Y + + ++ Sbjct: 141 --------------YNRDDDSLADIDYMGHGRDGGYAEYMALPAENAHVVATDLTDIELA 186 Query: 172 LIGCGFSTGYGSAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKF 230 C + TG ++ A++ G T V G GGVG +++ +A GA I K Sbjct: 187 TFCCAYLTG-ERMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAG--PGKE 243 Query: 231 AKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 A ++GA + + + V +D +++G + LL G Sbjct: 244 AAMLDIGAQAVV-TRGQGDLAEAVEAASGGRPIDVVADLVGGP--LFNDLLKILRPEGRY 300 Query: 291 VIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNI 350 G + L G+ G + + + + + L+ + Sbjct: 301 TTAGAIAGPVVQLDLRTMYLKQLELHGSSQGSRADFRRLVRYIEE-----KKIRPLVGGV 355 Query: 351 LPFEKINEG-FDLLRSGKSIRTVLT 374 P + + D + + V+ Sbjct: 356 YPLSEFHRAQTDFMAKNFVGKLVVV 380 >4A27-A nrPDB Length = 349 Score = 127 bits (318), Expect = 9e-30, Method: Composition-based stats. Identities = 69/397 (17%), Positives = 127/397 (31%), Gaps = 87/397 (21%) Query: 8 IKCKAAVLWELKK--PFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL--VTPLP 63 ++ +A VL + + P+ E++I++ A G+ D V GN+ P Sbjct: 2 MEMRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTP 61 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGT 123 ++ G E +GIVE++G+ V + GD+V+ +C E Y Sbjct: 62 LVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVY------------ 109 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 KI + F T Y Sbjct: 110 ------------------------------------KIPDDMSFSEAAAFPMNFVTAYVM 133 Query: 184 AVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +VA + G + V GGVG +V C + K K Sbjct: 134 LFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTAST-FKHEAIK----DSVT 188 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG----VPPD 298 + D + +K ++ GVD + + +T L + GT ++ G V + Sbjct: 189 HLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKG--LSLLKPLGTYILYGSSNMVTGE 246 Query: 299 SQNL-----------SINPMLLLTG-RTWKGAIFGGFKSKES--------VPKLVADFMA 338 +++ +NP+ L + G K+ V KL+ + Sbjct: 247 TKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQ 306 Query: 339 KKFSLDALITNILPFEKINEGFDLLRS-GKSIRTVLT 374 KK ++ ++ E++ E + G + +L Sbjct: 307 KKI--KPVVDSLWALEEVKEAMQRIHDRGNIGKLILD 341 >3HZZ-A nrPDB Length = 467 Score = 127 bits (318), Expect = 1e-29, Method: Composition-based stats. Identities = 70/392 (17%), Positives = 125/392 (31%), Gaps = 71/392 (18%) Query: 20 KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHV-------------VSGNLV-----TP 61 K ++EV V E + ++A+ + + G L Sbjct: 74 KSIHLDEVPVPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHD 133 Query: 62 LPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 LP I+G + AG+V G GV +PGD+V+ +CL +L +P Sbjct: 134 LPYHIIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELESP 175 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + ++ +V N + E+ G ST Sbjct: 176 DGHD---DTMLDPEQRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTA 232 Query: 181 YGSAVKV--AKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 Y V A + G ++G GG+G AG A I V + K + +G Sbjct: 233 YRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFA-LAGGANPICVVSSPQKAEICRSMG 291 Query: 238 ATECI----------------NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 A I +P+++K+ + + + +D FE GR + + Sbjct: 292 AEAIIDRNAEGYKFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGRE--TFGASV 349 Query: 282 CCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKF 341 GT + N L ++ + G+ F ++ +L+A K Sbjct: 350 YVTRKGGTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIA-----KG 404 Query: 342 SLDALITNILPFEKINEG----FDLLRSGKSI 369 + ++ E+ + L GK Sbjct: 405 KIHPTLSKTYSLEETGQAAYDVHRNLHQGKVG 436 >3SLK-A nrPDB Length = 795 Score = 125 bits (313), Expect = 4e-29, Method: Composition-based stats. Identities = 69/356 (19%), Positives = 110/356 (30%), Gaps = 60/356 (16%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGV 81 E AP EVRI M AAG+ D + G P LG E AG+V G GV Sbjct: 226 LVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMY--PGVASLGSEGAGVVVETGPGV 283 Query: 82 TTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 T + PGD+V+ + Sbjct: 284 TGLAPGDRVMGMIPKA-------------------------------------------- 299 Query: 142 VGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-G 200 F V D V +I A + + F T Y + V +A + PG + V Sbjct: 300 -----FGPLAVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSA 354 Query: 201 LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 GGVG++ + + GA + ++DK+ A EL + + Q+ L Sbjct: 355 AGGVGMAAIQLARHLGAE--VYATASEDKWQ-AVELSREHLASSRTC-DFEQQFLGATGG 410 Query: 261 GGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIF 320 GVD + + L G + +G + + + Sbjct: 411 RGVDVVLNSLAGE--FADASLRMLPRGGRFLELGKTDVRDPVEVADAHPGVSYQAFDTVE 468 Query: 321 GGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK-SIRTVLTF 375 G + + + + + L+ L + E L + + VLT Sbjct: 469 AGPQRIGEMLHELVELFEGRV-LEPLPVTAWDVRQAPEALRHLSQARHVGKLVLTM 523 >3FBG-A nrPDB Length = 346 Score = 120 bits (301), Expect = 9e-28, Method: Composition-based stats. Identities = 59/300 (19%), Positives = 104/300 (34%), Gaps = 66/300 (22%) Query: 18 LKKPFSIEE--------VEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHE 69 ++PF + + +++ PK HE+ +K+ + + D + V+ P +LG + Sbjct: 8 FEQPFKLSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD-VSKAPRVLGFD 66 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTR 129 A G+VESVG VT GD V +P Sbjct: 67 AIGVVESVGNEVTMFNQGDIVYYSGSPD-------------------------------- 94 Query: 130 RFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 + ++Y +++E VAK E+ + T Y + V Sbjct: 95 -------------QNGSNAEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFG 141 Query: 190 VT------PGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 ++ G T + G GGVG KA G R+I + K++GA + Sbjct: 142 ISRNRNENEGKTLLIINGAGGVGSIATQIAKAYG-LRVITTASRNETIEWTKKMGADIVL 200 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 N +K+ + K VD+ F D ++ + G + + Q+L Sbjct: 201 N---HKESLLNQFKTQGIELVDYVF-CTFNTDMYYDDMIQLVKPRGHIATIVAFENDQDL 256 >3TQH-A nrPDB Length = 321 Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats. Identities = 69/367 (18%), Positives = 122/367 (33%), Gaps = 75/367 (20%) Query: 11 KAAVLWELKKPFSIEEVEVAPPK--AHEVRIKMVAAGICRSDEHVVSG------NLVTPL 62 KA + P ++ V+ P+ +++ IK+ AA + D +G L L Sbjct: 8 KAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKNNL 67 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG 122 P LG++ +G V +G V V GDKV+ + C C Sbjct: 68 PSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C------------------ 107 Query: 123 TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 +++Y + + + + + T Sbjct: 108 ------------------------YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTAL- 142 Query: 183 SAVKVAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A+ A+V G + G GGVG + K G + +K A K LGA +C Sbjct: 143 QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKG--TTVITTASKRNHAFLKALGAEQC 200 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 IN + +L T VD +++G + + + C + G V V + Sbjct: 201 INYHEED----FLLAISTP--VDAVIDLVGGDVGIQS--IDCLKETGCIVSVPTITAGRV 252 Query: 302 LSINPMLLLTGRTWKGAIFGGFK--SKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359 + + + FG K + E + L K ++ I+ I + Sbjct: 253 IEV-------AKQKHRRAFGLLKQFNIEELHYLGKLVSEDKLRIE--ISRIFQLSEAVTA 303 Query: 360 FDLLRSG 366 +LL +G Sbjct: 304 HELLETG 310 >4A10-A nrPDB Length = 447 Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats. Identities = 65/387 (16%), Positives = 120/387 (31%), Gaps = 67/387 (17%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDE----------------HVV 54 K +++K + EV + EV + ++A+ I + + Sbjct: 39 KGVADKDVRKSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNAR 98 Query: 55 SGNLVTPL--PV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNY 111 G T P +LG + +G+V G GV KPGD VI Sbjct: 99 QGGWATRHDQPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHPA---------------- 142 Query: 112 CLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVC 171 + + G + ++Y VV + + A E+ Sbjct: 143 -----HVDEQEPATHGDGMLGTEQRAWGFETNFGGLAEYGVVRASQLLPKPAHLTWEEAA 197 Query: 172 LIGCGFSTGYGSAV--KVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKD 228 + T Y V + A++ G ++G GG+G + K G + V + Sbjct: 198 VSPLCAGTAYRMLVSDRGAQMKQGDIVLIWGASGGLGSYAIQFVKNGGGIPVAVV-SSAQ 256 Query: 229 KFAKAKELGATECINPQDY-------KKP---------IQEVLKEMTDGGVDFSFEVIGR 272 K A + LG IN + P + +++ E D FE GR Sbjct: 257 KEAAVRALGCDLVINRAELGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGR 316 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKL 332 + + GT V G + N L + + G+ + +++ +L Sbjct: 317 V--TFGLSVIVARRGGTVVTCGSSSGYLHTFDNRYLWMKLKKIVGSHGANHEEQQATNRL 374 Query: 333 VADFMAKKFSLDALITNILPFEKINEG 359 + ++ + P + E Sbjct: 375 FESGA-----VVPAMSAVYPLAEAAEA 396 >4Y1B-A nrPDB Length = 425 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 75/407 (18%), Positives = 140/407 (34%), Gaps = 68/407 (16%) Query: 1 MSTAGKVIKCKAAVLWELKKP---FSIEEVEVAPPKAHEVRIKMVAAGICRS-------- 49 + TA K + +P F E V+V P +V +K++AAG+ + Sbjct: 34 LGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGE 93 Query: 50 --DEHVVSGNLVTPLPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKN 106 D I G + +GIV +VG+GV +KPG +V+ L C+ Sbjct: 94 PLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGV-RLKPGAEVVVL---------ACRW 143 Query: 107 PESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASP 166 ES D+ + T+R + +F+Q+ VVDE Sbjct: 144 DES----AQDIRLGADPVTSSTQRVWGYEE------NYGSFAQFAVVDEYMCHPKPQRLS 193 Query: 167 LEKVCLIGCGFSTGYGSA--VKVAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAV 223 +T Y + V PG ++ G GG+G + + G + V Sbjct: 194 WAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVV 253 Query: 224 DINKDKFAKAKELGATECINPQDYKKPI-------QEVLKEMTDG--------------- 261 ++++ LGA I+ +++ +E +K+ DG Sbjct: 254 -SSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGER 312 Query: 262 -GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIF 320 E G DT+ S+ A + G + ++ + L + + +G+ Sbjct: 313 RAPRIVLEHSG-ADTIPTSIYMADNAGMVVICGGTTGYNGDVDLR-FLWMRQKRLQGSHA 370 Query: 321 GGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGK 367 + + +L+ +D ++ FE+I L+ + Sbjct: 371 ASAREAREITRLIDQGA-----IDPCLSRTFGFEEIGLAHQLIHDNQ 412 >2CDC-A nrPDB Length = 366 Score = 112 bits (279), Expect = 4e-25, Method: Composition-based stats. Identities = 68/380 (17%), Positives = 139/380 (36%), Gaps = 31/380 (8%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKA-HEVRIKMVAAGICRSDEHVVSGNLV-TPLP----- 63 KA ++ +++V+ + +++I+ + GIC +D +V+G L + LP Sbjct: 2 KAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKDF 61 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGT 123 ++LGHEA G+VE G GD V+P+ CG CR C ++C + G Sbjct: 62 LVLGHEAIGVVEESYHG---FSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIH 118 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 DG R P + + ++ + +A I+ + T Sbjct: 119 KMDGFMREWWYDDPKYLVKIPKSIEDIGILAQ-PLADIEKSIEEILEVQKRVPVWTCDDG 177 Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAK-AKELGATECI 242 + V G G +G+ + + G +A + + E T Sbjct: 178 TLNC------RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTNYY 231 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 N + +++ + G D + G ++ +++ G + G S ++ Sbjct: 232 NSSNGYDKLKDSV-----GKFDVIIDATGADVNILGNVIPLLGRNGVLGLFG-FSTSGSV 285 Query: 303 SIN----PMLLLTGRTWKGAIFG-GFKSKESVPKLVADFMAKKFSLDALITNILPFEKIN 357 ++ ++ T +T G + G +++V L + + LIT + Sbjct: 286 PLDYKTLQEIVHTNKTIIGLVNGQKPHFQQAVVHLASWKTLYPKAAKMLITKTVSINDEK 345 Query: 358 EGFDLLRSGK--SIRTVLTF 375 E +LR + I+ + + Sbjct: 346 ELLKVLREKEHGEIKIRILW 365 >4IDE-A nrPDB Length = 332 Score = 111 bits (278), Expect = 5e-25, Method: Composition-based stats. Identities = 76/372 (20%), Positives = 126/372 (33%), Gaps = 76/372 (20%) Query: 11 KAAVLWELKKPFSI----EEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV---TPLP 63 KA V E K + V V K +V IK+VAA + D G +PLP Sbjct: 25 KAWVYSEYGKTSDVLKFDPSVAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLP 84 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGT 123 I G++ AG+V VG VT K GD+V Sbjct: 85 TIPGYDVAGVVVKVGSQVTKFKVGDEVYGDLN---------------------------- 116 Query: 124 LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + + + ++YT DE +A + + T Sbjct: 117 -----------ETALVNPTRFGSLAEYTAADERVLAHKPKNLSFIEAASLPLAIETA-HE 164 Query: 184 AVKVAKVTPGSTCAVFGLGGVG-LSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 ++ A+++ G + V G G ++ K A +A + K + LGA I Sbjct: 165 GLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAATASTKKLDLLRTLGADLAI 224 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 + +E +++ + D ++ +G D ++ E IVG Sbjct: 225 DYT------KENFEDLPEK-FDVVYDAVGETD---KAVKAVKEGGKVVTIVG-------- 266 Query: 303 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDL 362 P +L T KG++ + KL + K T+ PF K+ E F Sbjct: 267 PATPPAILFVLTSKGSV---------LEKLKPYLESGKVKPVLDPTSPYPFTKVVEAFGY 317 Query: 363 LRSGK-SIRTVL 373 L S + + + V+ Sbjct: 318 LESSRATGKVVV 329 >2VN8-A nrPDB Length = 375 Score = 110 bits (276), Expect = 7e-25, Method: Composition-based stats. Identities = 78/414 (18%), Positives = 136/414 (32%), Gaps = 95/414 (22%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSI---EEVEVAPPK-AHEVRIKMVAAGICRSDEHVVSG 56 + T + A V+ + K + + + + +EV +K+ AA + D ++ SG Sbjct: 13 LGTENLYFQSMAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSG 72 Query: 57 NLVT----------------PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGK 100 T P+ LG + +G+V G V KPGD+V P Sbjct: 73 YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW--- 129 Query: 101 CRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAK 160 T S++ VV N V+ Sbjct: 130 ------------------------------------------KQGTLSEFVVVSGNEVSH 147 Query: 161 IDAASPLEKVCLIGCGFSTGYGSAVKVAKV----TPGSTCAVFGL-GGVGLSVVMGCKAA 215 + + + T + + KV + G + G GGVG + KA Sbjct: 148 KPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAW 207 Query: 216 GAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 A + AV ++D ++LGA + I+ + ++E LK + DF + +G Sbjct: 208 DA-HVTAV-CSQDASELVRKLGADDVIDYK--SGSVEEQLKSL--KPFDFILDNVGGSTE 261 Query: 276 MMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLV-- 333 A + T V + L+++ + + G G G K + Sbjct: 262 TWAPDFLKKWSGATYVTL---VTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYR 318 Query: 334 -ADFMAKK------------FSLDALITNILPFEKINEGFDLLRSGKS-IRTVL 373 A FMA + +I PF K+ E F + G + +TV+ Sbjct: 319 WAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 372 >2WEK-A nrPDB Length = 341 Score = 108 bits (270), Expect = 4e-24, Method: Composition-based stats. Identities = 50/274 (18%), Positives = 90/274 (32%), Gaps = 60/274 (21%) Query: 25 EEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT--PLPVILGHEAAGIVESVG-EGV 81 + V P ++ ++ G+ SD + +G P +G E G V ++G Sbjct: 23 RDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSAS 82 Query: 82 TTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 G V + Sbjct: 83 ARYTVGQAVA-------------------------------------------------Y 93 Query: 142 VGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-G 200 + +F++YTVV + + + P + + +T Y S ++ ++ G V Sbjct: 94 MAPGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVTAA 151 Query: 201 LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 GG G + K A +I + +K A K LG IN + +P+ VLK+ Sbjct: 152 AGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLGCDRPINYK--TEPVGTVLKQEYP 208 Query: 261 GGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 GVD +E +G M + G +++G Sbjct: 209 EGVDVVYESVGG--AMFDLAVDALATKGRLIVIG 240 >4EYE-A nrPDB Length = 342 Score = 107 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 69/374 (18%), Positives = 124/374 (33%), Gaps = 65/374 (17%) Query: 11 KAAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL--PVIL 66 KA L P +VE + V + + AAG+C D + G + P + Sbjct: 23 KAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVP 82 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 G E AG+V S EG + +KPGD+V+ Sbjct: 83 GIETAGVVRSAPEG-SGIKPGDRVMA---------------------------------- 107 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVK 186 F + +++ V + + + + + T Y + + Sbjct: 108 --------------FNFIGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYAR 153 Query: 187 VAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 ++ G T V GG+G + + K GA ++IAV K +GA + Sbjct: 154 RGQLRAGETVLVLGAAGGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVL--- 209 Query: 246 DYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304 ++ + ++E T G GVD + IG + + G ++VG Sbjct: 210 PLEEGWAKAVREATGGAGVDMVVDPIGGP--AFDDAVRTLASEGRLLVVGFAAGGIPTIK 267 Query: 305 NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDAL---ITNILPFEKINEGFD 361 LLL + G +G F + +K + + ++ +P + + Sbjct: 268 VNRLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEGMRPPVSARIPLSEGRQALQ 327 Query: 362 LLRSGKS-IRTVLT 374 GK + VL Sbjct: 328 DFADGKVYGKMVLV 341 >5A3V-A nrPDB Length = 329 Score = 107 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 61/359 (16%), Positives = 104/359 (28%), Gaps = 66/359 (18%) Query: 26 EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN----LVTPLPVILGHEAAGIVESVGEGV 81 +V V PK++EV +K+ A + D + G L P I + AG V VG GV Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGV 84 Query: 82 TTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHF 141 K GDKV+ + + Sbjct: 85 KNFKAGDKVVAVLS---------------------------------------------H 99 Query: 142 VGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTP---GST--C 196 +G +++ V E K + + T + A + G Sbjct: 100 LGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANI 159 Query: 197 AVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 V GGVG V K A A + A K LGA E + DYK P L Sbjct: 160 LVTAASGGVGHYAVQLAKLANA-HVTAT-CGARNIEFVKSLGADEVL---DYKTPEGAAL 214 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTW 315 K + D + + G + + P++ + ++ + Sbjct: 215 KSPSGKKYDAVVHCANGIP--FSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQL 272 Query: 316 KGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLT 374 + + K+ + +I + P K + + G + ++ Sbjct: 273 VPLLLIPKAENLEFMVN----LVKEGKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIV 327 >4DVJ-A nrPDB Length = 363 Score = 104 bits (260), Expect = 6e-23, Method: Composition-based stats. Identities = 58/310 (18%), Positives = 101/310 (32%), Gaps = 62/310 (20%) Query: 1 MSTAGKVIKCKAAVLWELKKPF----SIEEVEVAPPKA--HEVRIKMVAAGICRSDEHVV 54 + T + AV + P S+ ++E+ P H++ +++ A + D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 55 SGNLVTPLPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCL 113 ++G++AAGIV +VG VT +PGD+V + Sbjct: 73 RSTPPDGTDWKVIGYDAAGIVSAVGPDVTLFRPGDEVFYAGSI----------------- 115 Query: 114 KNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLI 173 + T +++ +VDE V + + + Sbjct: 116 ----------------------------IRPGTNAEFHLVDERIVGRKPKTLDWAEAAAL 147 Query: 174 GCGFSTGYGSAVKVAKVT---PGSTCAVF---GLGGVGLSVVMGCKAAGAARIIAVDINK 227 T + + V PG+ A+ G GGVG V + +IA Sbjct: 148 PLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIATASRP 207 Query: 228 DKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEAC 287 + K LGA I D+ KP+ + + G F F D A + Sbjct: 208 ETQEWVKSLGAHHVI---DHSKPLAAEVAALGLGAPAFVFSTT-HTDKHAAEIADLIAPQ 263 Query: 288 GTSVIVGVPP 297 G ++ P Sbjct: 264 GRFCLIDDPS 273 >3WID-A nrPDB Length = 369 Score = 102 bits (253), Expect = 4e-22, Method: Composition-based stats. Identities = 73/383 (19%), Positives = 127/383 (33%), Gaps = 37/383 (9%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLP--- 63 + A V K ++++ P+ +E ++K V GIC +D V+G L Sbjct: 1 MSTINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEG 60 Query: 64 ---VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120 ++LGHEA V V + +K GD V+PL + GKC C+ + C D Sbjct: 61 ENFLVLGHEALLQVLDVSDN-NYIKRGDFVVPLVR-RPGKCVNCRIGRQDNCSIGD---- 114 Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKID-AASPLEKVCLIGCGFST 179 D V V++ + KI PL+ V F Sbjct: 115 ----PDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDV 170 Query: 180 GYGSAVKVAKVTP--GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 ++ + G V G G K G + V+ + + K K + Sbjct: 171 VSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGF-DVTMVNRHDETENKMKMM- 228 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 D+ LK+M D +D + G T+ + G ++ G Sbjct: 229 -------DDFGVGFSNYLKDMPDK-IDLLVDTSGDPSTIFK-FVKKVNNNGVVILFGFNG 279 Query: 298 DSQNLSINPMLLLTGRTWKGAIFGG-----FKSKESVPKLVADFMAKKFSLDALITNILP 352 + +N + I G +++ L + ++ +IT Sbjct: 280 KAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAK 339 Query: 353 FEKINEGFDLLRSGKSIRTVLTF 375 E+ N F + I+TV+ + Sbjct: 340 PEETNIFFQKPKG--EIKTVIKW 360 >2VWH-A nrPDB Length = 357 Score = 100 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 72/384 (18%), Positives = 136/384 (35%), Gaps = 50/384 (13%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLP-----VI 65 KA + + + E P++ E ++ + G+ +D V++G P ++ Sbjct: 2 KAIAVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHG-GFPEGEDHLV 60 Query: 66 LGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQ 125 LGHEA G+V T ++ GD V+P R + + Y ++ Sbjct: 61 LGHEAVGVVVD--PNDTELEEGDIVVPTVR------RPPASGTNEYFERDQPD----MAP 108 Query: 126 DGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASP-----LEKVCLIGCGFSTG 180 DG S++ E + +I + +E + + Sbjct: 109 DGMYFERGI------VGAHGYMSEFFTSPEKYLVRIPRSQAELGFLIEPISITEKALEHA 162 Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKA--AGAARIIAV---DINKDKFAKAKE 235 Y A + A S+ V G G +GL + K G + + D +E Sbjct: 163 Y--ASRSAFDWDPSSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEE 220 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 L AT + Q + + +V ++M DF +E G + S+ G ++GV Sbjct: 221 LDATYVDSRQTPVEDVPDVYEQM-----DFIYEATGFPKHAIQSVQALA-PNGVGALLGV 274 Query: 296 PPD-SQNLSINPM---LLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNIL 351 P D + + ++L + G++ + V K+ L+ L+T + Sbjct: 275 PSDWAFEVDAGAFHREMVLHNKALVGSV--NSHVEHFEAATVTFTKLPKWFLEDLVTGVH 332 Query: 352 PFEKINEGFDLLRSGKSIRTVLTF 375 P + FD +I+T + F Sbjct: 333 PLSEFEAAFD--DDDTTIKTAIEF 354 >5LB9-A nrPDB Length = 385 Score = 80.9 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 51/299 (17%), Positives = 90/299 (30%), Gaps = 63/299 (21%) Query: 4 AGKVIKCKAAVLWELKKPFSIE-----EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNL 58 +I +A + + +P + E++ +EV +K + + + SD + + G Sbjct: 19 GRHMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVY 78 Query: 59 VTPL----------PVIL-GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNP 107 + P G+E V VG V++++ GD VIP Sbjct: 79 PSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIP--------------- 123 Query: 108 ESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPL 167 + G R F P + Sbjct: 124 -----SHVNFGTWRTHALGNDDDFIKLPNPAQSKANGK----------------PNGLTI 162 Query: 168 EKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF--GLGGVGLSVVMGCKAAGAARIIAVDI 225 + I Y K+TPG + G VG K I + Sbjct: 163 NQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRD 222 Query: 226 NK---DKFAKAKELGATECI-----NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTM 276 + A KELGAT+ I N +++ I+E +K+ + G + +G + Sbjct: 223 RPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQ-SGGEAKLALNCVGGKSST 280 >1V3V-A nrPDB Length = 333 Score = 78.6 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 46/232 (19%), Positives = 89/232 (38%), Gaps = 18/232 (7%) Query: 155 ENAVAKIDAASPLE-KVCLIGCGFSTGYGSAVKVAKVTPGSTCAV-FGLGGVGLSVVMGC 212 E + + PL + IG T Y ++V V G T V G VG V Sbjct: 107 EKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIA 166 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 K G +++ + +K A K++G N + ++E LK+ + G D F+ +G Sbjct: 167 KLKG-CKVVGAAGSDEKIAYLKQIGFDAAFNYKTV-NSLEEALKKASPDGYDCYFDNVGG 224 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP------MLLLTGRTWKGAIFGGFKS- 325 + ++L + G I G + P ++ +G I ++ Sbjct: 225 E--FLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESIIYKQLRIEGFIVYRWQGD 282 Query: 326 --KESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSI-RTVLT 374 ++++ L+ + K +T FE + F + +G ++ + V+T Sbjct: 283 VREKALRDLMKWVLEGKIQYHEHVTKG--FENMPAAFIEMLNGANLGKAVVT 332 >2Y05-A nrPDB Length = 328 Score = 74.0 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 40/226 (17%), Positives = 78/226 (34%), Gaps = 17/226 (7%) Query: 155 ENAVAKIDAASPLE-KVCLIGCGFSTGYGSAVKVAKVTPGSTCAV-FGLGGVGLSVVMGC 212 E + + PL + +G T Y +++ V G T V G VG V Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 161 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 K G +++ + +K A ++LG N + + ++E LK+ + G D F+ +G Sbjct: 162 KLKG-CKVVGAVGSDEKVAYLQKLGFDVVFNYKTV-ESLEETLKKASPDGYDCYFDNVGG 219 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAI---------FGGF 323 +++ + G I G P + + G Sbjct: 220 E--FSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGD 277 Query: 324 KSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSI 369 ++++ L+ + K I FE + F + G ++ Sbjct: 278 ARQKALKDLLKWVLEGKIQYKEYIIEG--FENMPAAFMGMLKGDNL 321 >5GXF-A nrPDB Length = 330 Score = 71.3 bits (173), Expect = 6e-13, Method: Composition-based stats. Identities = 53/265 (20%), Positives = 89/265 (33%), Gaps = 62/265 (23%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS--GNLVTPLPVIL 66 K +AAV K S+ ++ V EV + + + + D + G LV P + Sbjct: 15 KTQAAV-----KQLSLTDLPV-----GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVP 64 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQD 126 G + AG VE+ + KPGDKV+ + E++ Sbjct: 65 GIDFAGTVENSSD--ERYKPGDKVVLTGW---------RVGEAH---------------- 97 Query: 127 GTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS--A 184 +SQ V + + + + +G T + A Sbjct: 98 -----------------WGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMA 140 Query: 185 VKVAKVTPGS-TCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 ++ +TPG V G GGVG G + AV + LGAT+ + Sbjct: 141 LEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLG-YEVAAVTGRPETADYLTSLGATQIV 199 Query: 243 NPQDYKKPIQEVL-KEMTDGGVDFS 266 + + ++ L E+ G VD Sbjct: 200 ARDEINETVKRPLESEIWAGCVDAV 224 >1O89-A nrPDB Length = 345 Score = 65.1 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 54/323 (16%), Positives = 110/323 (34%), Gaps = 61/323 (18%) Query: 23 SIEEVEVAPPKAHEVRIKMVAAGICRSDEHVV--SGNLVTPLPVILGHEAAGIVESVGEG 80 S++ ++ + +V + + + + D + G ++ P+I G + AG V + Sbjct: 37 SVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRT--SE 94 Query: 81 VTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHH 140 G +V+ T G +H Sbjct: 95 DPRFHAGQEVL---------------------------------------LTGWGVGENH 115 Query: 141 FVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG--SAVKVAKVTP--GSTC 196 + ++ V + + + K +IG T A++ A V P G Sbjct: 116 W---GGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIV 172 Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 GGVG + V G +++AV + K LGA+ + P+D + + K Sbjct: 173 VTGASGGVGSTAVALLHKLG-YQVVAVSGRESTHEYLKSLGASRVL-PRDEFAESRPLEK 230 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD-SQNLSINPMLLLTGRT- 314 ++ G + + +G D ++A +L G G+ + ++ P +L R Sbjct: 231 QVWAG----AIDTVG--DKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQ 284 Query: 315 -WKGAIFGGFKSKESVPKLVADF 336 + + ++ +LVAD Sbjct: 285 GVDSVMTPPERRAQAWQRLVADL 307 >2J3K-A nrPDB Length = 345 Score = 61.6 bits (148), Expect = 6e-10, Method: Composition-based stats. Identities = 41/181 (22%), Positives = 66/181 (36%), Gaps = 14/181 (7%) Query: 125 QDGTRRFTCSGKPIHHFV----GVSTFSQYTVVDENAVAKID---AASPLEKVC-LIGCG 176 G R SG P + G+ + +Y+V+ A PL L+G Sbjct: 80 GYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMP 139 Query: 177 FSTGYGSAVKVAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAK- 234 T Y +V G T V G VG V K G ++ +K+K K Sbjct: 140 GMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG-CYVVGSAGSKEKVDLLKT 198 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + G + N ++ + + LK G+D FE +G M+ ++L G + G Sbjct: 199 KFGFDDAFNYKE-ESDLTAALKRCFPNGIDIYFENVGG--KMLDAVLVNMNMHGRIAVCG 255 Query: 295 V 295 + Sbjct: 256 M 256 >2VNA-A nrPDB Length = 357 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 59/375 (15%), Positives = 116/375 (30%), Gaps = 82/375 (21%) Query: 20 KPFSIEEVEVAP-PKAHEVRIKMVAAGICRSDEHVV-------SGNLVTPLPV--ILGHE 69 + F +EEV + +V+++ + + D ++ + +TP + ++ Sbjct: 22 ENFRMEEVYLPDNINEGQVQVRTLYLSV---DPYMRCRMNEDTGTDYITPWQLSQVVDGG 78 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTR 129 GI+E T + GD V + P + DG Sbjct: 79 GIGIIEE--SKHTNLTKGDFVTSFYWP----------------------WQTKVILDGNS 114 Query: 130 RFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 + + + + IG T + Sbjct: 115 LEKVDPQLVDGHLSYF------------------------LGAIGMPGLTSLIGIQEKGH 150 Query: 190 VTPGS--TCAVFGL-GGVGLSVVMGCKAAGAARIIAV-DINKDKFAKAKELGATECINPQ 245 +T GS T V G G G G +R++ + ++ ELG IN + Sbjct: 151 ITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYK 210 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG---------VP 296 K + E L+E GVD F+ +G + +++ ++ G Sbjct: 211 --KDNVAEQLRESCPAGVDVYFDNVGG--NISDTVISQMNENSHIILCGQISQYNKDVPY 266 Query: 297 PDSQNLSINPMLLLTGRTWKGAIFGGFKSKES--VPKLVADFMAKKFSLDALITNILPFE 354 P + +I + T + + +K K + +L F K + + N E Sbjct: 267 PPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKETVING--LE 324 Query: 355 KINEGFDLLRSGKSI 369 + F + +G +I Sbjct: 325 NMGAAFQSMMTGGNI 339 >2ZB3-A nrPDB Length = 353 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 36/220 (16%), Positives = 72/220 (32%), Gaps = 22/220 (10%) Query: 170 VCLIGCGFSTGYGSAVKVAKVTPGS--TCAVFGL-GGVGLSVVMGCKAAGAARIIAV-DI 225 + IG T + ++ GS T V G G G G +R++ + Sbjct: 132 LGAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGT 191 Query: 226 NKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHE 285 + ELG +N + + E L+E GGVD F+ +G + +++ Sbjct: 192 QEKCLFLTSELGFDAAVNYK--TGNVAEQLREACPGGVDVYFDNVGG--DISNAVISQMN 247 Query: 286 ACGTSVIVG---------VPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKES--VPKLVA 334 ++ G P ++ + T + +K K + +L Sbjct: 248 ENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLNYKDKFEPGILQLSQ 307 Query: 335 DFMAKKFSLDALITNILPFEKINEGFD-LLRSGKSIRTVL 373 F K + + E + F ++ G + ++ Sbjct: 308 WFKEGKLKVKETMAKG--LENMGVAFQSMMTGGNVGKQIV 345 >1ZCJ-A nrPDB Length = 463 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 178 STGYGSAVKVAKVTPGSTCAVFGLGGVG-LSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 ST G++ K A P S+ V GLG +G + + ++AV+ + + AK++ Sbjct: 22 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >3ZWA-A nrPDB Length = 742 Score = 41.6 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 178 STGYGSAVKVAKVTPGSTCAVFGLGGVG-LSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 ST G++ K A P S+ V GLG +G + + ++AV+ + + AK++ Sbjct: 301 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >2EGU-A nrPDB Length = 308 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 2/64 (3%) Query: 183 SAVKVAKVTPGSTCA--VFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +A K K+ PG T G G+GL++V K A ++ ++ ++ + GA Sbjct: 55 AAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAEL 114 Query: 241 CINP 244 + P Sbjct: 115 VLTP 118 >4DIO-A nrPDB Length = 405 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 28/113 (24%), Positives = 42/113 (37%), Gaps = 9/113 (7%) Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 + A P + V G G GL + + GA + A D+ + LGA Sbjct: 177 ALPMMMTAAGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAK 235 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI 292 I +D +E T GG ++ E+ G A+L+ H A VI Sbjct: 236 -FIAVED-----EEFKAAETAGG--YAKEMSGEYQVKQAALVAEHIAKQDIVI 280 >3MGG-A nrPDB Length = 276 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 41/108 (37%), Gaps = 9/108 (8%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKP 250 PG+ G G +G V+ K A I ++DI+ + KA+E I N + + Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQAN 95 Query: 251 IQEVLKEMTDGGVDFSFEV-----IGRLDTMMASLLCCHEACGTSVIV 293 I + D D F + + + SL + GT ++ Sbjct: 96 IFSL--PFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >5ILO-A nrPDB Length = 271 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 36/105 (34%), Gaps = 12/105 (11%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT----------ECINPQ 245 G GG+GL V AAGAA++ +D+ + K A + N + Sbjct: 19 VVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKK 78 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 + +E+ K T G +D V G + G Sbjct: 79 GVEATYEEIAK--TFGNIDIVVNVAGIFNDKDVQRTLLVNLGGII 121 >5JE5-A nrPDB Length = 247 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 49/139 (35%), Gaps = 25/139 (17%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G + GAA+++ VDI++ A+E + Y P++ Sbjct: 42 GKSVLDLACG-FGFFGREIYR-RGAAKVVGVDISEKMIELARE-------ESRKYGDPLE 92 Query: 253 EVLKEMTD----GGVDFS--------FEVIGRLDTMMASLLCCHEACGTSVIVGVPPD-- 298 ++++ + G D + + L M + + G V V PD Sbjct: 93 FHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPDFS 152 Query: 299 --SQNLSINPMLLLTGRTW 315 N + + +L R W Sbjct: 153 LAKGNFAKYGVNVLNERAW 171 >2VHY-A nrPDB Length = 377 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 41/151 (27%), Gaps = 16/151 (10%) Query: 161 IDAASPLEKVCLIGCGFSTGYGSAVKVAK----------VTPGSTCAVFGLGGVGLSVVM 210 + +P+ +V Y V P V G G G + Sbjct: 127 LPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPAD-VVVIGAGTAGYNAAR 185 Query: 211 GCKAAGAARIIAVDINKDKFAK--AKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE 268 GA + +DIN DK + A+ G Y+ ++ G V Sbjct: 186 IANGMGA-TVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAV--LVP 242 Query: 269 VIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 + SL+ + V + + Sbjct: 243 GAKAPKLVSNSLVAHMKPGAVLVDIAIDQGG 273 >3X2F-A nrPDB Length = 411 Score = 37.7 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 26/148 (17%), Positives = 45/148 (30%), Gaps = 14/148 (9%) Query: 174 GCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA 233 G G ST + G V G G G + + GA R+I +++ K Sbjct: 178 GTGQSTWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVK---- 232 Query: 234 KELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 A E I P++E +K DF G D + + + Sbjct: 233 ----AVEAIMDGFTVMPMKEAVKI-----ADFVITASGNTDVLSKEDILSLKDGAVLANA 283 Query: 294 GVPPDSQNLSINPMLLLTGRTWKGAIFG 321 G + + + + + + G Sbjct: 284 GHFNVEIPVRVLEEIAVEKFEARPNVTG 311 >6BII-A nrPDB Length = 333 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 30/78 (38%), Gaps = 10/78 (12%) Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 + + + G T + G G +G ++ K G I K KELGA Sbjct: 137 AWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMR--ILYTARSRKPEAEKELGAE 194 Query: 240 ECINPQDYKKPIQEVLKE 257 KP++E+L+E Sbjct: 195 F--------KPLEELLRE 204 >1X14-A nrPDB Length = 401 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 40/107 (37%), Gaps = 17/107 (15%) Query: 149 QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA--------------KVTPGS 194 TV+ ++V +I A L+ + + GY + V+ A P + Sbjct: 116 NVTVMAMDSVPRISRAQSLDALSSM--ANIAGYRAIVEAAHEFGRFFTGQITAAGKVPPA 173 Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 V G G GL+ + + GA + A D + + + +GA Sbjct: 174 KVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGAEFL 219 >2B25-A nrPDB Length = 336 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 42/117 (35%), Gaps = 14/117 (11%) Query: 189 KVTPGSTCAVFGLGGVGLSVVMGCKAAGA-ARIIAVDINKDKFAKAKELGATE-----CI 242 + PG T G G G + KA G+ R+I+ ++ KD AK+ Sbjct: 102 DINPGDTVLEAGSGS-GGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLS 160 Query: 243 NPQDYKKPIQEVLKEMTDGGVDF---SFEVIG----RLDTMMASLLCCHEACGTSVI 292 + +++ + + K+++ D +F+ + + + G + Sbjct: 161 HVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLKHGGVCAV 217 >1BW9-B nrPDB Length = 356 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 28/106 (26%), Positives = 41/106 (38%), Gaps = 10/106 (9%) Query: 166 PLEKVCLIGCGFSTGYGS--------AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGA 217 LE+ F+T G A + G T V GLG VG S+ AGA Sbjct: 141 SLERGGAGSSAFTTAVGVFEAMKATVAHRGLGSLDGLTVLVQGLGAVGGSLASLAAEAGA 200 Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGV 263 +++ D + ++ A A LG + +D +V GGV Sbjct: 201 -QLLVADTDTERVAHAVALG-HTAVALEDVLSTPCDVFAPCAMGGV 244 >1XLT-A nrPDB Length = 384 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 + + A P + VFG+G GL + K GA ++A D+ + + LG Sbjct: 159 AFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLG 215 >5EKU-A nrPDB Length = 390 Score = 36.2 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 + V+ I+A + + + Y +K VTP + G G GL +M Sbjct: 55 ARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKK-HVTPETGVLEIGAGS-GLLSLM 112 Query: 211 GCKAAGAARIIAVDINKDKFAKAKE 235 K GA ++AV+ +++ A+E Sbjct: 113 AAK-LGAKWVVAVEGSEELAKLARE 136 >4M36-A nrPDB Length = 343 Score = 36.2 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210 + V+ I+A + + + Y +K VTP + G G GL +M Sbjct: 20 ARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKK-HVTPETGVLEIGAGS-GLLSLM 77 Query: 211 GCKAAGAARIIAVDINKDKFAKAKE 235 K GA ++AV+ +++ A+E Sbjct: 78 AAK-LGAKWVVAVEGSEELAKLARE 101 >1VH3-A nrPDB Length = 262 Score = 36.2 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 37/101 (36%), Gaps = 3/101 (2%) Query: 179 TGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGA 238 T A + PG A + V +GA+R+I N++ AK GA Sbjct: 4 TVIIPARFASSRLPGKPLADIKGKPMIQHVFEKALQSGASRVIIATDNENVADVAKSFGA 63 Query: 239 TEC---INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTM 276 C +N + + EV++++ + + G + Sbjct: 64 EVCMTSVNHNSGTERLAEVVEKLAIPDNEIIVNIQGDEPLI 104 >4INE-A nrPDB Length = 454 Score = 36.2 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 40/112 (35%), Gaps = 8/112 (7%) Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + PG T G+G +G G + +D++ + A A E E + + Sbjct: 235 RFGDFKPGQTMLDIGVG-IGGGARQVADEFGV-HVHGIDLSSNMLAIALER-LHEEKDSR 291 Query: 246 DYKKPIQEVLKEMTDGGVDFSF--EVIGRL---DTMMASLLCCHEACGTSVI 292 ++ + D D+ F + I + + + + + + G +I Sbjct: 292 VKYSITDALVYQFEDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKVLI 343 >3VPX-A nrPDB Length = 364 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA-KELGATEC 241 G T AV G+G V ++ GA ++I DIN++ +A GAT Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGA-KLIITDINEEAVQRAVDAFGATAV 221 >6BQC-A nrPDB Length = 383 Score = 35.8 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 53/132 (40%), Gaps = 18/132 (13%) Query: 185 VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAAR----IIAVDINKDKFAKAKEL--GA 238 + ++ PG G G GL+ A+ ++ V I+ ++ A+E G Sbjct: 161 CEKLQLKPGMRVLDIGCGWGGLA------HYMASNYDVSVVGVTISAEQQKMAQERCEGL 214 Query: 239 TECINPQDYKKPIQEVLKEMTDGGVDFSFEVIG--RLDTMMASLLCCHEACGTSVIVGVP 296 I QDY+ + + ++ G FE +G DT A + + G ++ + Sbjct: 215 DVTILLQDYRDLNDQFDRIVSVG----MFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIG 270 Query: 297 PDSQNLSINPML 308 +L+++P + Sbjct: 271 SKKTDLNVDPWI 282 >6ACF-A nrPDB Length = 367 Score = 35.4 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAG--AARIIAVDINKDKFAKA-KELGATECINPQDYKK 249 G AV G VG C+ A++I DINK+ A+A +E GA ++P D Sbjct: 173 GKVVAVQG---VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAK-AVDPNDIYG 228 Query: 250 PIQEVLKEMTDGGV 263 ++ GG+ Sbjct: 229 VECDIFAPCALGGI 242 >5Z1Z-A nrPDB Length = 329 Score = 35.4 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 39/100 (39%), Gaps = 6/100 (6%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK-PI 251 G T V G G +G++++ K G R++A D A A ELG P + + + Sbjct: 144 GKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYVDLPTLFSESDV 200 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV 291 + +T E D M ++ + + G + Sbjct: 201 ISLHCPLTPENYHLLNEAA--FDQMKNGVMIVNTSRGALI 238 >1V8B-A nrPDB Length = 479 Score = 35.0 bits (79), Expect = 0.050, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 40/124 (32%), Gaps = 16/124 (12%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G VG K GA R+ +I+ +A G Sbjct: 257 GKIVVICGYGDVGKGCASSMKGLGA-RVYITEIDPICAIQAVMEGFNVV----------- 304 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTG 312 L E+ D G DF G +D + L + +V+ + + +N + G Sbjct: 305 -TLDEIVDKG-DFFITCTGNVDVIK--LEHLLKMKNNAVVGNIGHFDDEIQVNELFNYKG 360 Query: 313 RTWK 316 + Sbjct: 361 IHIE 364 >4XIJ-A nrPDB Length = 275 Score = 35.0 bits (79), Expect = 0.054, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 23/59 (38%), Gaps = 4/59 (6%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK----FAKAKELGA 238 V A T G + V G GG + V+ G RI V ++ K A+ GA Sbjct: 117 GVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARRCGA 175 >4K2X-A nrPDB Length = 523 Score = 34.7 bits (78), Expect = 0.061, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT----ECINPQDYKKPI 251 + G G GL + + AGA R + ++ + +K LG E ++ + + Sbjct: 25 VVIAGAGPTGLMLACELRLAGA-RTLVLERLAEPVDFSKALGVHARTVELLDMRGLGEGF 83 Query: 252 QEVLKEMTDGGV 263 Q ++ G Sbjct: 84 QAEAPKLRGGNF 95 >1V9L-A nrPDB Length = 421 Score = 34.3 bits (77), Expect = 0.082, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 168 EKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 E G +T A K+ G T A+ G+G VG + GA I DIN Sbjct: 186 EYATGFGVAVATR-EMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDIN 243 >4N7R-A nrPDB Length = 472 Score = 34.3 bits (77), Expect = 0.085, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 32/69 (46%), Gaps = 6/69 (8%) Query: 173 IGCGFSTGYGSAVKVAKVTPGST------CAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 I G + +AV++A + + V G G +G V+ A G +++ V+ + Sbjct: 181 IASGAVSVSSAAVELALMKLPQSSNVSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRS 240 Query: 227 KDKFAKAKE 235 +++ + +E Sbjct: 241 EERVSAIRE 249 >5JJC-A nrPDB Length = 342 Score = 34.3 bits (77), Expect = 0.087, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 23/60 (38%), Gaps = 2/60 (3%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAV--DINKDKFAKAKELGATEC 241 A K + PG G G+ + M KA G I + +++K + LGA Sbjct: 53 AEKRGLLRPGGVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELI 112 >5F8E-A nrPDB Length = 377 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 48/117 (41%), Gaps = 10/117 (8%) Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYK 248 + G+ A FG G G +V + +A GA+R +D + + A E A + N + Sbjct: 185 LRSGADVADFGCGS-GRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFER 243 Query: 249 KPIQEVLKEMTDGGVDF--SFEVI---GRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 + E+ K G D F+ I + ++ ++ G ++V + SQ Sbjct: 244 HDLAELDKV---GAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQ 297 >1DXY-A nrPDB Length = 333 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 19/53 (35%), Gaps = 2/53 (3%) Query: 181 YGSAVKVAKVTPGS-TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAK 232 Y A G T V G G +G + K GA ++IA D K Sbjct: 132 YEKAGTFIGKELGQQTVGVMGTGHIGQVAIKLFKGFGA-KVIAYDPYPMKGDH 183 >2O23-A nrPDB Length = 265 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY--KKPIQE 253 G G+GL+ GA+ ++ N A+AK+LG P D +K +Q Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 254 VLKEMTD--GGVDFSFEVIGRLDTMMA 278 L G VD + G Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVASKT 102 >1EUF-A nrPDB Length = 227 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 39/96 (40%), Gaps = 9/96 (9%) Query: 111 YCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPL-EK 169 +CL + + G R T P+ + ++ T+ ++ + K+ + + +K Sbjct: 44 HCLGSSINVTLGAHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDK 103 Query: 170 VCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVG 205 V I +A+V PG C+V G G +G Sbjct: 104 VSPI--------NLPRSLAEVKPGMMCSVAGWGRLG 131 >1W1U-A nrPDB Length = 557 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 35/98 (35%), Gaps = 7/98 (7%) Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 G GLGG+G + + AGA + ++ + + E T ++ Q Sbjct: 160 HYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACSLN-IESQQSRIDFRLE---TRYVDEQ 215 Query: 246 --DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 D + + K T G S + G ++ L+ Sbjct: 216 ATDLDDALVRIAK-YTAEGKAISIALHGNAAEILPELV 252 >5JXW-A nrPDB Length = 498 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 36/111 (32%), Gaps = 14/111 (12%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG G GA R+I +I+ +A G + + Sbjct: 270 AGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEIDPICALQASMEGYQVSV--------L 320 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 ++V+ E D G D + + + +G D ++ Sbjct: 321 EDVVSE-----ADIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDV 366 >2YVG-A nrPDB Length = 408 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 46/138 (33%), Gaps = 17/138 (12%) Query: 162 DAASPLEKVCLIGCGFSTGYGSAVKV-AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARI 220 A P + + A ++ A + P S + G G +GL + + AG + Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGV-HV 171 Query: 221 IAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE--VIGRLDTMMA 278 V+ ++A V + GVD FE V G +D ++ Sbjct: 172 SLVETQPRLMSRA------------APATLADFVARYHAAQGVDLRFERSVTGSVDGVV- 218 Query: 279 SLLCCHEACGTSVIVGVP 296 L V+VG+ Sbjct: 219 LLDDGTRIAADMVVVGIG 236 >3D2L-A nrPDB Length = 243 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 23/52 (44%), Gaps = 4/52 (7%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 A + +V PG A G G G + ++ + VD++++ A+E Sbjct: 25 AWVLEQVEPGKRIADIGCGT-GTATLLLADHY---EVTGVDLSEEMLEIAQE 72 >3KYD-B nrPDB Length = 551 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%) Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 G ++A+ G V G GG+G ++ G + I +D++ Sbjct: 8 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >3KYC-B nrPDB Length = 660 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%) Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 G ++A+ G V G GG+G ++ G + I +D++ Sbjct: 26 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >5AOV-A nrPDB Length = 336 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 10/65 (15%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G T + G G +G ++ K I K KELGA +P++ Sbjct: 150 GKTIGIVGFGRIGQAIARRAKGFNMR--ILYYSRTRKSQAEKELGAEY--------RPLE 199 Query: 253 EVLKE 257 EVLKE Sbjct: 200 EVLKE 204 >4CUK-A nrPDB Length = 338 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T V G G +G++ + K G R++A D A +LG Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPS--TAALDLGVEYV 189 >1JWB-B nrPDB Length = 249 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 S + GLGG+G + +AG + +D + Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >6C55-A nrPDB Length = 340 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 22/65 (33%), Gaps = 1/65 (1%) Query: 177 FSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 +T Y G AV G G G + K G +I + + F KAKE Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRS-FDKAKED 59 Query: 237 GATEC 241 G Sbjct: 60 GFDVF 64 >5D84-A nrPDB Length = 326 Score = 33.1 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVD--INKDKFAKAKELGATE 240 +K +T + G +G+++ M K G VD I+ K GA Sbjct: 57 HGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGA-- 114 Query: 241 CINPQDYKKP 250 N + ++P Sbjct: 115 --NVEMVEEP 122 >3EGI-A nrPDB Length = 206 Score = 32.7 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAK 234 V GVG + + R+IA+DI+ K A A+ Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 82 >3GDH-A nrPDB Length = 241 Score = 32.7 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAK 234 V GVG + + R+IA+DI+ K A A+ Sbjct: 81 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 117 >2EEZ-A nrPDB Length = 369 Score = 32.7 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 35/115 (30%), Gaps = 1/115 (0%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + + G G VG + GA ++ +D+N + ++ I + I++ Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 255 LKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 309 ++ + +L + V V V +I P Sbjct: 227 VQHADLLIGAVLVPGAKAPKLVTRDMLSLMKEGAVIVDVAVDQGGCVETIRPTTH 281 >4COO-A nrPDB Length = 563 Score = 32.7 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 26/67 (38%), Gaps = 2/67 (2%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAV--DINKDKFAKAKELGATEC 241 A + + PG T G G+ + + G II + ++ +K + LGA Sbjct: 152 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 211 Query: 242 INPQDYK 248 P + + Sbjct: 212 RTPTNAR 218 >1E3W-A nrPDB Length = 261 Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 6/88 (6%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 G G+GLS GA ++ N + +AK+LG P + +EV Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE-KEVQ 72 Query: 256 KEMTD-----GGVDFSFEVIGRLDTMMA 278 +T G +D + G + Sbjct: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKT 100 >1M54-A nrPDB Length = 363 Score = 32.4 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 26/67 (38%), Gaps = 2/67 (2%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAV--DINKDKFAKAKELGATEC 241 A + + PG T G G+ + + G II + ++ +K + LGA Sbjct: 87 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 146 Query: 242 INPQDYK 248 P + + Sbjct: 147 RTPTNAR 153 >4FS8-A nrPDB Length = 383 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 46/134 (34%), Gaps = 12/134 (8%) Query: 104 CKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDA 163 C + C K+ G +++D + + S V E+ + Sbjct: 5 CASG----CQKSKNGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILAD 60 Query: 164 ASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGA-ARIIA 222 + GCG + +++ G+T G G G V + K G ++I Sbjct: 61 IADEVLEKFYGCGSTLPADGSLE------GATVLDLGCGT-GRDVYLASKLVGEHGKVIG 113 Query: 223 VDINKDKFAKAKEL 236 VD+ ++ A++ Sbjct: 114 VDMLDNQLEVARKY 127 >5VMT-A nrPDB Length = 342 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 57/180 (31%), Gaps = 24/180 (13%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAV---------------DINKDKFAKAKELGAT 239 A+ G G +G + + A + AV D + +F EL Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 240 E-CINPQDYKKPIQEVLKEMTDG--GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 +N ++ K +E+ G GVD E G T A V++ P Sbjct: 72 AIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFF-TNKTKAEAHIRAGARKVVISAP 130 Query: 297 PDSQNLSI---NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPF 353 + ++ +L G + + + + A + ++ L+T I + Sbjct: 131 GGNDVKTVVYGVNQDILDGSETVISA--ASCTTNCLAPMAAVLQKEFGVVEGLMTTIHAY 188 >5MMS-A nrPDB Length = 408 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 26/67 (38%), Gaps = 2/67 (2%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAV--DINKDKFAKAKELGATEC 241 A + + PG T G G+ + + G II + ++ +K + LGA Sbjct: 130 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 189 Query: 242 INPQDYK 248 P + + Sbjct: 190 RTPTNAR 196 >1ZFN-A nrPDB Length = 253 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 16/38 (42%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFA 231 S + GLGG+G + AG ++ D + + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLS 68 >4XGI-A nrPDB Length = 436 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 19/48 (39%) Query: 177 FSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVD 224 F G +A K G+ AV G G VG + AGA I D Sbjct: 215 FVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQD 262 >2BHS-A nrPDB Length = 303 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 40/94 (42%), Gaps = 3/94 (3%) Query: 184 AVKVAKVTPGSTC--AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A K ++ PG A G G+ L+++ K ++ ++++++ A + GA Sbjct: 52 AEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELI 111 Query: 242 INPQDYK-KPIQEVLKEMTDGGVDFSFEVIGRLD 274 + ++ + +++ EM + G + D Sbjct: 112 LVTKEQGMEGARDLALEMANRGEGKLLDQFNNPD 145 >1CYD-A nrPDB Length = 244 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 193 GSTCAVFGLG-GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 G V G G G+G V A+GA + N D + AKE Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKE 50 >5UYY-A nrPDB Length = 381 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 20/43 (46%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 + G G +G S+ + K I DI +++ +AKEL Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKEL 60 >3G1U-A nrPDB Length = 437 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK 227 G TC V G G VG +A GA R++ +++ Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP 245 >3X43-A nrPDB Length = 332 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 23/63 (36%), Gaps = 2/63 (3%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAV--DINKDKFAKAKELGATEC 241 A + PG T G VG+++ M A G + + + ++ + G Sbjct: 54 AEAKGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLV 113 Query: 242 INP 244 + P Sbjct: 114 LFP 116 >3AOE-A nrPDB Length = 424 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 19/48 (39%) Query: 177 FSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVD 224 F T +A K+ G+ A+ G G VG + GA + D Sbjct: 203 FITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQD 250 >4K28-A nrPDB Length = 269 Score = 31.6 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 20/49 (40%) Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK 229 G+A K G V G GGVG ++ AG A I D + + Sbjct: 113 LGAAHKHGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTAR 161 >2EKL-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T + G G +G V + A G +++A DI + KA+++ A Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGM-KVLAYDILDIR-EKAEKINAKAV 188 >3FBT-A nrPDB Length = 282 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 44/136 (32%), Gaps = 26/136 (19%) Query: 180 GYGSAVKVAKVT-PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK--------- 229 G+G + +V + C V G GG +V+ K A I V N +K Sbjct: 108 GFGKMLSKFRVEIKNNICVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEKTSEIYGEFK 167 Query: 230 ---FAKAKELGATECIN-------PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMAS 279 + + L IN P++ + P+ + + VD + + Sbjct: 168 VISYDELSNLKGDVIINCTPKGMYPKEGESPVDKEVVAKFSSAVDLIYN------PVETL 221 Query: 280 LLCCHEACGTSVIVGV 295 L G + G+ Sbjct: 222 FLKYARESGVKAVNGL 237 >1XDW-A nrPDB Length = 331 Score = 31.6 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 33/99 (33%), Gaps = 9/99 (9%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPIQ 252 T V GLG +G GA +I D+ + K ++ E + D Sbjct: 148 TVGVVGLGRIGRVAAQIFHGMGA-TVIGEDVFEIKGIEDYCTQVSLDEVLEKSDIITIHA 206 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV 291 +KE G + + L M + + A G V Sbjct: 207 PYIKE---NGAVVTRDF---LKKMKDGAILVNCARGQLV 239 >3D3W-A nrPDB Length = 244 Score = 31.6 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 192 PGSTCAVFGLG-GVGLSVVMGCKAAGAARIIAVDINKDKFA 231 G V G G G+G V A GA R++AV + Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGA-RVVAVSRTQADLD 45 >1GPJ-A nrPDB Length = 404 Score = 31.2 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 182 GSAVKVAKVTPGS----TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK-FAKAKEL 236 +AV++A+ GS T V G G +G +V G ++ + ++ A++L Sbjct: 152 SAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDL 211 Query: 237 GATEC 241 G Sbjct: 212 GGEAV 216 >3BKX-A nrPDB Length = 275 Score = 31.2 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 178 STGYGSAV-KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDI 225 T + A+ + +V PG G G LS V+ + + + +DI Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDI 76 >4YRY-B nrPDB Length = 468 Score = 31.2 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 39/113 (34%), Gaps = 8/113 (7%) Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 + G AV G G + GA ++ V ++ A+ + ++ Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHAL-----EE 330 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 I+ + + + + + G ++ M + EA G+ VP + N Sbjct: 331 GIEFLWLTLP---IRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNF 380 >3JTJ-A nrPDB Length = 253 Score = 31.2 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 40/123 (32%), Gaps = 8/123 (6%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK--- 248 PG A + + V+ A+GA R+I + D + G C+ D++ Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDT-----MMASLLCCHEACGTSVIVGVPPDSQNLS 303 + + EV++ D V G + + VP S + Sbjct: 80 ERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEA 139 Query: 304 INP 306 NP Sbjct: 140 FNP 142 >1I9G-A nrPDB Length = 280 Score = 31.2 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 7/114 (6%) Query: 185 VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAG-AARIIAVDINKDKFAKAKEL--GATEC 241 V + PG+ G G G + +A G A ++I+ + D A+ G Sbjct: 92 VHEGDIFPGARVLEAGAGS-GALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGC-YG 149 Query: 242 INPQDYKKPIQEVL-KEMTDGGVD-FSFEVIGRLDTMMASLLCCHEACGTSVIV 293 P +++ + ++ E+ DG VD +++ + + A V V Sbjct: 150 QPPDNWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMVYV 203 >3OAM-A nrPDB Length = 252 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 39/107 (36%), Gaps = 5/107 (4%) Query: 179 TGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA-KELG 237 T A + PG A G + V AGA R+I + ++ +A + G Sbjct: 4 TVVIPARYQSTRLPGKPLADIGGKPMIQWVYEQAMQAGADRVIIAT-DDERVEQAVQAFG 62 Query: 238 ATECI---NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 C+ N Q + + EV+ +M V G + +++ Sbjct: 63 GVVCMTSPNHQSGTERLAEVVAKMAIPADHIVVNVQGDEPLIPPAII 109 >4KIC-A nrPDB Length = 357 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 35/196 (17%), Positives = 63/196 (32%), Gaps = 26/196 (13%) Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK------DKFAKA 233 + +AV TP +T A G G G ++ + R + VDI +K A Sbjct: 167 AFWAAVDGLGYTP-TTVADLGSGS-GERLIQIARRFPGVRGLGVDIADGAIAMAEKEVAA 224 Query: 234 KELGATECINPQDYKKPIQEVLKEMTDGGVDFSF------------EVIGRLDTMMASLL 281 K G + + + I +V VD + L + A+ Sbjct: 225 KGFG-DQISFVRGDARTIDQVSARGEFAEVDLLTCFMMGHDFWPRENCVQTLRKLRAAFP 283 Query: 282 CCHEA--CGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAK 339 + VG+P + L + + G G + V + K Sbjct: 284 NVRRFLLGDATRTVGIP--DRELPVFTLGFEFGHDMMGVYLPTLDEWDGVFEEGGWRCVK 341 Query: 340 KFSLDAL-ITNILPFE 354 K ++D+L ++ + E Sbjct: 342 KHAIDSLSVSVVFELE 357 >6IQV-A nrPDB Length = 340 Score = 31.2 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 1/62 (1%) Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 N + Y +P + + + + GVDF E G T A +A V++ P S Sbjct: 75 NYRVYAEPQAQNIPWVKNDGVDFVLECTG-FYTSKAKSQAHLDAGAKRVLISAPAGSDLK 133 Query: 303 SI 304 +I Sbjct: 134 TI 135 >1VE9-A nrPDB Length = 347 Score = 31.2 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 E +E+ GG D G ++ G + V P Sbjct: 165 ESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAP 208 >5U9P-A nrPDB Length = 265 Score = 30.8 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 10/88 (11%) Query: 193 GSTCAVFGLG-GVGLSVVMGCKAAGAARIIAVDINKDKFA-KAKE-----LGATECINPQ 245 G + G G G+GL++ G AGAA I+ D N++K A A+ A + Sbjct: 20 GRRALITGSGRGIGLTLARGLAEAGAA-IVINDRNEEKAATLARRFRDEGFAADHAVFDV 78 Query: 246 DYKKPIQEVLKEMTD--GGVDFSFEVIG 271 ++ + E G +D G Sbjct: 79 AEHAQVRAAIDEFEARVGAIDILVNNAG 106 >3CJR-A nrPDB Length = 254 Score = 30.8 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 34/88 (38%), Gaps = 9/88 (10%) Query: 174 GCGFSTGYGSAVKVA------KVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK 227 G F TG+ ++A + PG G G G+ + K G A + VDI+ Sbjct: 96 GMAFGTGHHETTRLALKALARHLRPGDKVLDLGTGS-GVLAIAAEKLGGKA--LGVDIDP 152 Query: 228 DKFAKAKELGATECINPQDYKKPIQEVL 255 +A+ + P+ + ++ L Sbjct: 153 MVLPQAEANAKRNGVRPRFLEGSLEAAL 180 >4OM8-A nrPDB Length = 309 Score = 30.8 bits (68), Expect = 0.96, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 41/120 (34%), Gaps = 13/120 (10%) Query: 195 TCAVFGLGGVG-LSVVMGCKAAGAARIIAVDINKDKFAKAKEL--GATECINPQDYKKPI 251 A+ GLG +G + G +++A D+ +A+ + A ++ P Sbjct: 4 NIAIIGLGTMGPGMAARLAR--GGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 252 QEV--LKEMTD-----GGVDFSFEVIGRLDTMMASLLCCHEAC-GTSVIVGVPPDSQNLS 303 V ++ D G D E + ++ A + + G IV ++ Sbjct: 62 AGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPIT 121 >5OHX-A nrPDB Length = 504 Score = 30.8 bits (68), Expect = 1.00, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Query: 184 AVKVAKVTPGSTCA--VFGLGGVGLSVVMGCKAAGAARIIAV--DINKDKFAKAKELGAT 239 A + PG T G G+GL+ M G II + ++ +K + LGA Sbjct: 89 AEDKGLLKPGCTIIEPTSGNTGIGLA--MAAAVRGYKCIIVMPEKMSDEKISTLYALGAK 146 Query: 240 ECINPQD 246 P + Sbjct: 147 IIRTPTE 153 >6J0Z-C nrPDB Length = 491 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 S V G G GL + + AG + ++ +D + +++ LG Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG 48 >2X36-A nrPDB Length = 207 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 15/114 (13%) Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLS 207 + Y V + + + + GC T + + +A P V + Sbjct: 80 NDYLVTSHIHL-HVPEGATPKDGPSAGCTIVT---ALLSLAMGRP-----------VRQN 124 Query: 208 VVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 + M + + +I+ V K+K AK G T + P + KK ++ +T+G Sbjct: 125 LAMTGEVSLTGKILPVGGIKEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEG 178 >1EUA-A nrPDB Length = 213 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 32/141 (22%), Positives = 47/141 (33%), Gaps = 25/141 (17%) Query: 208 VVMGCKA--AGAARIIAVDINKDK-----FAKAKEL-----GATECINPQDYKKPIQEVL 255 V KA AG R++ V + + A AKE+ GA +NPQ L Sbjct: 29 AVPMAKALVAGGVRVLEVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQ--------L 80 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHE-ACGTSV----IVGVPPDSQNLSINPMLLL 310 E+T+ G F+ + A+ G S ++G+ + P Sbjct: 81 AEVTEAGAQFAISPGLTEPLLKAATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEAN 140 Query: 311 TGRTWKGAIFGGFKSKESVPK 331 G AI G F P Sbjct: 141 GGVKALQAIAGPFSQVRFCPT 161 >6GME-A nrPDB Length = 201 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 223 VDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV 269 VD+ ++ A LGAT IN ++++ + E++ F+ ++ Sbjct: 62 VDVREEGKENAFSLGATLWINSEEFED-LDEIVARYVQPMASFARDL 107 >2HMT-A nrPDB Length = 144 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S+V G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE--- 62 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 63 --LLSLGIRNFEYVIVAIGA 80 >3EMK-A nrPDB Length = 246 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 27/84 (32%), Gaps = 5/84 (5%) Query: 193 GSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G GG+G ++ A GA + + A ELG + P + Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDRE 66 Query: 252 Q----EVLKEMTDGGVDFSFEVIG 271 E GGVD G Sbjct: 67 AVKALGQKAEEEMGGVDILVNNAG 90 >2ZJ1-A nrPDB Length = 495 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 31/102 (30%), Gaps = 14/102 (13%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G VG K GA R+ +I+ +A G ++ Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVV--------TVE 325 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 E + G D G D +M + + +G Sbjct: 326 EAI-----GDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG 362 >5BUT-A nrPDB Length = 288 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S+V G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE--- 62 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 63 --LLSLGIRNFEYVIVAIGA 80 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S+V G ++AVDIN++K I N + + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE--- 204 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 205 --LLSLGIRNFEYVIVAIGA 222 >4PZE-A nrPDB Length = 284 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 16/38 (42%), Gaps = 1/38 (2%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAK 232 T + G G +G + C G ++ VDI+ K Sbjct: 5 TVGIVGAGTMGNGIAQACAVVG-LNVVMVDISDAAVQK 41 >1HL3-A nrPDB Length = 358 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/24 (45%), Positives = 14/24 (58%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAG 216 G T + GLG VG +V + KA G Sbjct: 171 GETLGIIGLGRVGQAVALRAKAFG 194 >3TNL-A nrPDB Length = 315 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 179 TGYGSAVKVAK-VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 TGY A+K A G + G GG ++ + G I + D +A A++ Sbjct: 139 TGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEK 196 >2ISQ-A nrPDB Length = 320 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 32/99 (32%), Gaps = 8/99 (8%) Query: 184 AVKVAKVTPGSTCAV---FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 A K + PG + + G GVGL+ K + ++ ++ G Sbjct: 55 AEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVEL 114 Query: 241 CIN-----PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLD 274 + + +E+L + +G + FE Sbjct: 115 VLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPK 153 >2BRY-A nrPDB Length = 497 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 14/40 (35%) Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIA 222 + + + C V G G GL + GA ++ Sbjct: 82 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >4TXK-A nrPDB Length = 615 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 14/40 (35%) Query: 183 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIA 222 + + + C V G G GL + GA ++ Sbjct: 74 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >6GBN-A nrPDB Length = 438 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 27/94 (28%), Gaps = 14/94 (14%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG + AGA R+I +I+ +A A + + + Sbjct: 218 AGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQA----AMDGYEVKKMADAV 272 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHE 285 + D G + + Sbjct: 273 KR---------ADIVVTATGNKNIITGEHFKAMR 297 >6APH-A nrPDB Length = 445 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 23/71 (32%), Gaps = 5/71 (7%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG + AG + + +I+ +A A E + + Sbjct: 225 AGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQA----AMEGYEVKQLDTVV 279 Query: 252 QEVLKEMTDGG 262 +T G Sbjct: 280 DNADIIITTTG 290 >2JC3-A nrPDB Length = 303 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 40/94 (42%), Gaps = 3/94 (3%) Query: 184 AVKVAKVTPGSTC--AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A K ++ PG A G G+ L+++ K ++ ++++++ A + GA Sbjct: 52 AEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELI 111 Query: 242 INPQDYK-KPIQEVLKEMTDGGVDFSFEVIGRLD 274 + ++ + +++ M++ G + D Sbjct: 112 LVTKEQGMEGARDLALAMSERGEGKLLDQFNNPD 145 >6FZI-A nrPDB Length = 332 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 38/131 (29%), Gaps = 26/131 (19%) Query: 195 TCAVFGLGGVGLSVVMG-----------------CKAAGAARIIAVDINKDKF--AKAKE 235 A+ G G +G + K A + D + +F + Sbjct: 3 KVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTL--AHLFKYDSAQGRFNGEIEVK 60 Query: 236 LGATECINPQDYKKPIQEVLKEMTDG--GVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 GA +N ++ K + E+ G GVD E G + + VI Sbjct: 61 EGA-FVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVI- 118 Query: 294 GVPPDSQNLSI 304 P +L Sbjct: 119 -SAPAGNDLPT 128 >4DIM-A nrPDB Length = 403 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 24/72 (33%), Gaps = 6/72 (8%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPI 251 + G G L + K G I N K A E+ + NP + Sbjct: 8 KRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNLADEISYMDISNP----DEV 63 Query: 252 QEVLKEMTDGGV 263 ++ +K++ G Sbjct: 64 EQKVKDLNLDGA 75 >4FHN-X nrPDB Length = 450 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 21/55 (38%), Gaps = 7/55 (12%) Query: 179 TGYG------SAVKVAKVT-PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 TGYG + +K + G +V G G V + GA I A D + Sbjct: 214 TGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSS 268 >3NJ4-A nrPDB Length = 435 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK-DKFAKAKE 235 G V G G VG + GA R+I +I+ + A E Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAME 258 >1QO8-A nrPDB Length = 566 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 17/40 (42%), Gaps = 1/40 (2%) Query: 188 AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK 227 A + + V G G G + + K AGA +I VD Sbjct: 116 AGPSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAP 154 >5ZBK-A nrPDB Length = 203 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 22/58 (37%), Gaps = 7/58 (12%) Query: 173 IGCGFSTGYGSAVKVAKVTPGSTCA------VFGLGGVGLS-VVMGCKAAGAARIIAV 223 + CG S G + A V G A V+G G VGL V A +I + Sbjct: 8 VFCGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGTVADAALAAGGEVIGI 65 >3DC2-A nrPDB Length = 529 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 13/28 (46%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARI 220 G T V GLG +G V A GA + Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVV 169 >1WG8-A nrPDB Length = 285 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 3/60 (5%) Query: 177 FSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL 236 Y A+ + V PG LGG G + + + R+I +D + + A+AK L Sbjct: 7 VPVLYQEALDLLAVRPGGVYVDATLGGAGHARGILER---GGRVIGLDQDPEAVARAKGL 63 >4MOP-A nrPDB Length = 633 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 8/67 (11%) Query: 196 CAVFGLGGVGLSVVMGCK-AAGAA-RIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + G G +G + GA ++ DI + ++GA + N +Y+K I + Sbjct: 49 VVIVGSGPIG---CTYARELVGAGYKVAMFDIGE--IDSGLKIGAHKK-NTVEYQKNIDK 102 Query: 254 VLKEMTD 260 + + Sbjct: 103 FVNVIQG 109 >4J90-A nrPDB Length = 222 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 29/80 (36%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S+ G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSICKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE--- 62 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 63 --LLSLGIRNFEYVIVAIGA 80 >2WWR-A nrPDB Length = 330 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 21/52 (40%), Gaps = 1/52 (1%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 ST + GLG +G ++ K G R + + +A E A P+ Sbjct: 156 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP-RPEEAAEFQAEFVSTPE 206 >2RIR-A nrPDB Length = 300 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 GS AV GLG G+++ A GA + + A+ E+G Sbjct: 157 GSQVAVLGLGRTGMTIARTFAALGA-NVKVGARSSAHLARITEMG 200 >2NVU-B nrPDB Length = 805 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 28/69 (40%), Gaps = 3/69 (4%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 V G GG+G ++ +G +I +D++ + L P+D +P EV Sbjct: 413 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVS---NLNRQFLFRPKDIGRPKAEV 469 Query: 255 LKEMTDGGV 263 E + V Sbjct: 470 AAEFLNDRV 478 >1YOV-B nrPDB Length = 444 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 27/69 (39%), Gaps = 3/69 (4%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 V G GG+G ++ +G +I +D++ + P+D +P EV Sbjct: 52 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQ---FLFRPKDIGRPKAEV 108 Query: 255 LKEMTDGGV 263 E + V Sbjct: 109 AAEFLNDRV 117 >1LTH-T nrPDB Length = 319 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAG-AARIIAVDINKDKFAK 232 V P AV G G VG ++ G A I+ DI K++ Sbjct: 5 VKPTK-LAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >1FI8-A nrPDB Length = 228 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 31/98 (31%), Gaps = 7/98 (7%) Query: 111 YCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKV 170 +C + + G + P+ + ++ T+ ++ + K+ + + Sbjct: 45 HCSGSKIQVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 104 Query: 171 CLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSV 208 + KV PG C V G G +G Sbjct: 105 VK-------PLNLPRRNVKVKPGDVCYVAGWGKLGPMG 135 >2AS0-A nrPDB Length = 396 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 18/47 (38%), Gaps = 4/47 (8%) Query: 190 VTPGSTCA-VFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 V PG VF G + AGA +I +D + AKE Sbjct: 215 VQPGDRVLDVFTY--TGGFAIHAA-IAGADEVIGIDKSPRAIETAKE 258 >4KUG-A nrPDB Length = 290 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 29/207 (14%), Positives = 61/207 (29%), Gaps = 33/207 (15%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA--------KELGATECINPQ 245 V G G +G +V A G +I DI ++ + +L A E I Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKG-CEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 246 DYKKPIQEVLKEMT-------DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298 D ++ + + D V+ + E + + A L + Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILASNTSSLS 120 Query: 299 SQNLS--------------INPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLD 344 ++ NP ++ ++ ++V ++ + Sbjct: 121 ITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVA 180 Query: 345 ---ALITNILPFEKINEGFDLLRSGKS 368 + N + INE +L+ G + Sbjct: 181 EAPGFVVNRILIPMINEATFILQEGVA 207 >3ZZN-A nrPDB Length = 310 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 25/81 (30%), Gaps = 4/81 (4%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + G G VG + G AR + + K A+A A + ++ + P+ Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAH---AEDILHATPFAHPVWVW 58 Query: 255 LKEMTD-GGVDFSFEVIGRLD 274 D G G Sbjct: 59 AGSYGDLEGARAVVLAAGVAQ 79 >3F9I-A nrPDB Length = 249 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 5/46 (10%) Query: 193 GSTCAVFGLG-GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 237 G T + G G+G ++ G +++I N++K K LG Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLG-SKVIISGSNEEKL---KSLG 55 >5UJU-A nrPDB Length = 576 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 20/73 (27%), Gaps = 4/73 (5%) Query: 220 IIAVDINKDKFAKAKELGATE----CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 +IA D A E+ A I + GGV S + G + Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 276 MMASLLCCHEACG 288 ++ G Sbjct: 523 NQSAAFSDFHGTG 535 >3HDH-A nrPDB Length = 302 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 V G G +G + A G ++ VD +D AK+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >3OND-A nrPDB Length = 488 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA 233 G V G G VG K AGA R+I +I+ +A Sbjct: 264 AGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPICALQA 304 >6DLL-A nrPDB Length = 398 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 11/27 (40%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIA 222 A+ G G GL + AG II Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIV 34 >5FUB-A nrPDB Length = 337 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 16/44 (36%) Query: 199 FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 G G + L + K AG + A + + K+ G + Sbjct: 53 CGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVV 96 >4DIB-A nrPDB Length = 345 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 47/128 (36%), Gaps = 19/128 (14%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN--KDKFAKAKELGA-----TECINPQDY 247 A+ G G +G V A I+A++ + + A + + + Sbjct: 6 RVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFED 65 Query: 248 KKPIQEVLKEM-----------TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 + + + TD GV+ E G+ ++ ++L EA VI+ P Sbjct: 66 HLLVDGKMIRLLNNRDPKELPWTDLGVEVVIEATGKFNSKEKAILHV-EAGAKKVILTAP 124 Query: 297 PDSQNLSI 304 +++++I Sbjct: 125 GKNEDVTI 132 >1F14-A nrPDB Length = 310 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 V G G +G + A G ++ VD +D AK+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >2YFH-A nrPDB Length = 448 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 21/55 (38%), Gaps = 7/55 (12%) Query: 179 TGYG------SAVKVAKVT-PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 TGYG + +K + G +V G G V + GA I A D + Sbjct: 210 TGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSS 264 >6HNS-A nrPDB Length = 454 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 11/27 (40%), Gaps = 3/27 (11%) Query: 195 TCAVFGLGGVGLS---VVMGCKAAGAA 218 A+ G G GL+ A GAA Sbjct: 4 RVAIIGAGPCGLAQLRAFQSAAAKGAA 30 >3WGE-A nrPDB Length = 113 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 24/75 (32%), Gaps = 2/75 (2%) Query: 83 TVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGN--PRGTLQDGTRRFTCSGKPIHH 140 V GD I F P CG C+ L + G + CSG + Sbjct: 17 HVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 76 Query: 141 FVGVSTFSQYTVVDE 155 + + F VD+ Sbjct: 77 YPTLLWFRDGKKVDQ 91 >5M0P-A nrPDB Length = 428 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 17/120 (14%), Positives = 43/120 (35%), Gaps = 15/120 (12%) Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFS--------------FEVIGRLDTMMASLLC 282 GA ++ + + + MT+G +++ E + ++ S++ Sbjct: 88 GAIHTVDGKKHVDRKALFMSLMTEGNLNYVRELTRTLWHANTQRMESMDEVNIYRESIVL 147 Query: 283 CHEACGTSVIVGVPPDSQNLSINPMLLLTGR-TWKGAIFGGFKSKESVPKLVADFMAKKF 341 + V PP+ M ++ G F G+K+ + + V D++ ++ Sbjct: 148 LTKVGTRWAGVQAPPEDIERIATDMDIMIDSFRALGGAFKGYKASKEARRRVEDWLEEQI 207 >5TQV-A nrPDB Length = 233 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 28/80 (35%), Gaps = 2/80 (2%) Query: 194 STCAVFGLG-GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 T + G G+G V + G +IA + A + LGA + I Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGW-NVIATARDDASLAALRALGAHAHALDITQPEQIA 68 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 + ++ +D + V G Sbjct: 69 ALGWKLDGERLDVAVVVSGV 88 >4F86-A nrPDB Length = 320 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 25/64 (39%), Gaps = 6/64 (9%) Query: 186 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFA----KAKELGATEC 241 + V PG T G G G V+ ++ V ++ + +A+ELG + Sbjct: 119 HLGPVGPGDTLVDAGCGRGGSMVM--AHQRFGCKVEGVTLSAAQAEFGNRRARELGIDDH 176 Query: 242 INPQ 245 + + Sbjct: 177 VRSR 180 >2QHR-L nrPDB Length = 218 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 17/43 (39%) Query: 264 DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306 D + + G DT+ + ++G P + L++ P Sbjct: 86 DEAIYICGVGDTIKEQFVYVFGGGTKVTVLGQPKSTPTLTVFP 128 >5XW3-A nrPDB Length = 315 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 23/66 (34%), Gaps = 4/66 (6%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK---DKFAKAKELGATE 240 A++ VT G T G G + R+I K +K K LGAT Sbjct: 55 ALEKGLVTEGGTIIEPTAGNTG-IGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATV 113 Query: 241 CINPQD 246 P + Sbjct: 114 VHTPTE 119 >2DR1-A nrPDB Length = 386 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 23/58 (39%), Gaps = 1/58 (1%) Query: 149 QYTVVDENAVAKIDAASPLEKVCLIGCGFS-TGYGSAVKVAKVTPGSTCAVFGLGGVG 205 +Y V + V ++ +EK ++ S TG A V+ G V +G G Sbjct: 50 EYRKVHMDTVERLREFLEVEKGEVLLVPSSGTGIMEASIRNGVSKGGKVLVTIIGAFG 107 >2YU3-A nrPDB Length = 95 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 316 KGAIFGGFKSKESVPKLVADFMAKKFSLDAL-ITNILPFEKINEGFDLLRSGKSIRTV 372 G + G ++ V +++ D K + + LP +IN+ L S K I+ V Sbjct: 29 AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDVRYKSNLPLTEINKILKNLESKKLIKAV 86 >2DK5-A nrPDB Length = 91 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 316 KGAIFGGFKSKESVPKLVADFMAKKFSLDAL-ITNILPFEKINEGFDLLRSGKSIRTV 372 G + G ++ V +++ D K + + LP +IN+ L S K I+ V Sbjct: 12 AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDVRYKSNLPLTEINKILKNLESKKLIKAV 69 >5NMX-A nrPDB Length = 425 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 10/22 (45%) Query: 195 TCAVFGLGGVGLSVVMGCKAAG 216 AV G G GL+ K AG Sbjct: 3 RVAVLGAGPSGLTAARYLKQAG 24 >4GCM-A nrPDB Length = 312 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 36/224 (16%), Positives = 62/224 (27%), Gaps = 57/224 (25%) Query: 196 CAVFGLGGVGLSVVMGCKAA--------------------------GAARIIAVDINKDK 229 A+ G G G++ + A G I D++ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKM 68 Query: 230 FAKAKELGATE---------------CINPQDYKKPIQEVL----KEMTDGGVDFSFEVI 270 F AK+ GA IN + + + V+ E GV E+ Sbjct: 69 FEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELG 128 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVP 330 GR + A ++G + T + + Sbjct: 129 GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIV-----HRRDELRAQ 183 Query: 331 KLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLT 374 +++ D K +D + ++ L INE + GK LT Sbjct: 184 RILQDRAFKNDKIDFIWSHTLK--SINE-----KDGKVGSVTLT 220 >3FEO-A nrPDB Length = 437 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 7/23 (30%), Positives = 10/23 (43%) Query: 44 AGICRSDEHVVSGNLVTPLPVIL 66 IC SD H V + P++ Sbjct: 93 CNICGSDIHPVGWCAASGKPLVP 115 >6ABI-A nrPDB Length = 358 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 20/71 (28%), Gaps = 3/71 (4%) Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMM 277 +II DI K+ GA K + E +T G D D + Sbjct: 27 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLT-KGYDVV--CGFANDNIN 83 Query: 278 ASLLCCHEACG 288 + G Sbjct: 84 KETIDIMAENG 94 >2E28-A nrPDB Length = 587 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 42/124 (33%), Gaps = 12/124 (9%) Query: 176 GFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235 +AV+ V G + VG G+ ++ V + D AK + Sbjct: 432 MLDVAVDAAVRSGLVKHGDLVVITAGVPVG--------ETGSTNLMKVHVISDLLAKGQG 483 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV-IGRLDTMMASLLCCHEACG---TSV 291 +G K +E ++M DGG+ + + + + E G + Sbjct: 484 IGRKSAFGKAVVAKTAEEARQKMVDGGILVTVSTDADMMPAIEKAAAIITEEGGLTSHAA 543 Query: 292 IVGV 295 +VG+ Sbjct: 544 VVGL 547 >3H9U-A nrPDB Length = 436 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK-DKFAKAKE 235 G T V G G VG + GA R++ +++ + A E Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAME 253 >3GRP-A nrPDB Length = 266 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 31/84 (36%), Gaps = 5/84 (5%) Query: 193 GSTCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY--KK 249 G V G GG+G ++ A GA + A +LG + + +K Sbjct: 27 GRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDRK 86 Query: 250 PIQEV--LKEMTDGGVDFSFEVIG 271 I+++ + E G+D G Sbjct: 87 SIKQLAEVAEREMEGIDILVNNAG 110 >1KZH-A nrPDB Length = 555 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 10/81 (12%) Query: 131 FTCSGKPIHHFVGVSTFSQY-TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAK 189 + S P+ HF G S + + D + + + V LI G TGY S +K Sbjct: 415 YKGSFTPVDHFFGYEGRSAFPSNFDSDYCYSLGYNA----VVLILNGL-TGYMSCIKNLN 469 Query: 190 VTPGSTCAVFGLGGVGLSVVM 210 + P GGV L+++M Sbjct: 470 LKPTDWI----AGGVPLTMLM 486 >1YPF-A nrPDB Length = 336 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 7/60 (11%) Query: 189 KVTPGSTCAV-----FGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE--LGATEC 241 + PG C FG GG L+ + C A + IIA + AK GAT Sbjct: 177 GIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTNGDVAKSIRFGATMV 236 >3PPI-A nrPDB Length = 281 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 27/81 (33%), Gaps = 3/81 (3%) Query: 200 GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG--ATEC-INPQDYKKPIQEVLK 256 G GG+G + V A G +IA + A A ELG A N + + Sbjct: 38 GAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSVLAAIEA 97 Query: 257 EMTDGGVDFSFEVIGRLDTMM 277 G + ++ G Sbjct: 98 ANQLGRLRYAVVAHGGFGVAQ 118 >3H5A-A nrPDB Length = 358 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 14/30 (46%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVD 224 + G GG+G V + +G II +D Sbjct: 117 KVVILGCGGIGNHVSVILATSGIGEIILID 146 >1DOD-A nrPDB Length = 394 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 11/26 (42%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARII 221 A+ G G GL + AG +I Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVI 30 >3JTM-A nrPDB Length = 351 Score = 28.5 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 18/49 (36%), Gaps = 1/49 (2%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T G G +G ++ K G ++ D + KE GA Sbjct: 164 GKTIGTVGAGRIGKLLLQRLKPFG-CNLLYHDRLQMAPELEKETGAKFV 211 >4D3F-A nrPDB Length = 310 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 27/74 (36%), Gaps = 1/74 (1%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + V GLG +G ++ G + + + K + GA + + Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYS-VTVWNRTSSKADQLVAKGAIRVSTVNEALAANEL 80 Query: 254 VLKEMTDGGVDFSF 267 V+ +TD V +S Sbjct: 81 VILSLTDYNVMYSI 94 >4P4L-A nrPDB Length = 277 Score = 28.5 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 37/111 (33%), Gaps = 9/111 (8%) Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG-----ATEC--INPQDYKK 249 V G GG + V+G G I V N DK A+ +LG AT + Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFDSGGLAD 180 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGT--SVIVGVPPD 298 + ++ + + G L + L ++ T + VG Sbjct: 181 AVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGG 231 >3GDF-A nrPDB Length = 267 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 40/118 (33%), Gaps = 13/118 (11%) Query: 193 GSTCAVFGLG---GVGLSVVMGCKAAGAAR-IIAVDINKDKFAKAKELGATECINPQDYK 248 G V G G+G+ GC GAA I + KEL T I + YK Sbjct: 20 GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYK 79 Query: 249 ------KPIQEVLKEMTD--GGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298 + ++++K++ G +D G L EA V V + Sbjct: 80 CQVDSYESCEKLVKDVVADFGQIDAFIANAGATAD-SGILDGSVEAWNHVVQVDLNGT 136 >4WJI-A nrPDB Length = 293 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 44/131 (33%), Gaps = 3/131 (2%) Query: 194 STCAVFGLGGVGLSVVMGCK-AAGAARIIAVDINKDKFAKAKE--LGATECINPQDYKKP 250 T A+ G+G +G S+ + A I+ ++ +A E LG ++ + + Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELGLGDRYTLSAAEAVEG 64 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 310 V+ + G I A + G+ + P +++ P + Sbjct: 65 ADLVVVSVPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPKDVHFVPGHPI 124 Query: 311 TGRTWKGAIFG 321 G G G Sbjct: 125 AGTEHSGPDAG 135 >4IZO-A nrPDB Length = 419 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 16/36 (44%), Gaps = 1/36 (2%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINK 227 PG+ + G G +G +A G R+ +D + Sbjct: 34 PGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDP 68 >3NNK-A nrPDB Length = 411 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 16/42 (38%) Query: 172 LIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 213 ++ G S A+ V+ + PG V G G + + Sbjct: 67 MLVDGTSRAGIEAILVSAIRPGDKVLVPVFGRFGHLLCEIAR 108 >3IC9-A nrPDB Length = 492 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 37/132 (28%), Gaps = 7/132 (5%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGA-ARIIAVDINKDKF--AKAKELGATECINPQDYKKP 250 + AVFG G +GL + G ++ + + K A + N + Y Sbjct: 175 KSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRY-AEKTFNEEFYFDA 233 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV---GVPPDSQNLSINPM 307 V+ + S A G V G+ S L Sbjct: 234 KARVISTIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNS 293 Query: 308 LLLTGRTWKGAI 319 L T + ++ Sbjct: 294 PLFDELTLQTSV 305 >3HM2-A nrPDB Length = 178 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 16/120 (13%), Positives = 37/120 (30%), Gaps = 2/120 (1%) Query: 184 AVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 A+ P T G GG G + ++ + +I++++ + ++ Sbjct: 17 AISALAPKPHETLWDIG-GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVS 75 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIG-RLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 + + + D F G + A+ G V V +S+ + Sbjct: 76 DRIAVQQGAPRAFDDVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQM 135 >3AOE-E nrPDB Length = 419 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 24/76 (31%), Gaps = 6/76 (7%) Query: 168 EKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDI-- 225 + +G A + G+ V GLG VG +V + + G + Sbjct: 194 DDAAGLG-ALLVLEALAKRRGLDLRGARVVVQGLGQVGAAVALHAERLGMRVVAVATSMG 252 Query: 226 ---NKDKFAKAKELGA 238 + A+ L A Sbjct: 253 GMYAPEGLDVAEVLSA 268 >3TQD-A nrPDB Length = 256 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 26/73 (35%) Query: 192 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 PG + V +GA ++ +K A++ GA C+ D++ Sbjct: 24 PGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKRIRQVAEDFGAVVCMTSSDHQSGT 83 Query: 252 QEVLKEMTDGGVD 264 + + + G + Sbjct: 84 ERIAEAAVALGFE 96 >1B26-A nrPDB Length = 416 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 2/53 (3%) Query: 176 GFSTGYGSAVKVAKVTPGS-TCAVFGLGGVG-LSVVMGCKAAGAARIIAVDIN 226 G G A+ V + P T AV G G VG + ++ + G+ + D Sbjct: 192 GVKVCAGLAMDVLGIDPKKATVAVQGFGNVGQFAALLISQELGSKVVAVSDSR 244 >5MH6-A nrPDB Length = 308 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 28/147 (19%), Positives = 43/147 (29%), Gaps = 16/147 (10%) Query: 74 VESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTC 133 VE GE PGD V G + + +C++ + + + Sbjct: 32 VEFAGED-EQFGPGDAVASF-----GHRDAFLDADWVHCIRAGYDEFPVGVYEEAGTYLT 85 Query: 134 SGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 193 + IH T + Y + + A L Y +A G Sbjct: 86 NSTGIHGTTVGETVAGYMLTFARRLHAYRDAQHDHAWDL------PRYEEPFTLA----G 135 Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARI 220 V GLG +G VV A G + Sbjct: 136 ERVCVVGLGTLGRGVVDRAAALGMEVV 162 >1LSS-A nrPDB Length = 140 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 35/111 (31%), Gaps = 4/111 (3%) Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV---AKVTPGS-TCAVFGLGGVGLSVV 209 + + ID + I G + +K A + AV G V L Sbjct: 28 HDIVLIDIDKDICKKASAEIDALVINGDCTKIKTLEDAGIEDADMYIAVTGKEEVNLMSS 87 Query: 210 MGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 + K+ G + IA + + LG ++P+ E L E Sbjct: 88 LLAKSYGINKTIARISEIEYKDVFERLGVDVVVSPELIAANYIEKLIERPG 138 >3OC4-A nrPDB Length = 452 Score = 28.1 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 13/28 (46%) Query: 182 GSAVKVAKVTPGSTCAVFGLGGVGLSVV 209 G+ V + T AV G G +G+ + Sbjct: 136 GALAAVPLLENSQTVAVIGAGPIGMEAI 163 >3HWR-A nrPDB Length = 318 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 30/102 (29%), Gaps = 5/102 (4%) Query: 193 GSTCAVFGLGGVGL-SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G A+ G G VG M +A +IA + G D + + Sbjct: 19 GMKVAIMGAGAVGCYYGGMLARAGHEVILIA---RPQHVQAIEATGLRLETQSFDEQVKV 75 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 G D + DT A+L A S +V Sbjct: 76 SASSDPSAVQGADLVLFCVKSTDTQSAAL-AMKPALAKSALV 116 >2YQ5-A nrPDB Length = 343 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 195 TCAVFGLGGVGLSVVMGCKAAGAARIIAVDI 225 T + G+G +G +V A GA ++IA D+ Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGA-KVIAYDV 179 >1L1F-A nrPDB Length = 505 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 3/41 (7%) Query: 189 KVTPG---STCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 +TPG T V G G VGL + GA I + + Sbjct: 241 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESD 281 >4ZV2-A nrPDB Length = 233 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 58/159 (36%), Gaps = 23/159 (14%) Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMM 277 +++ DI+ K A AK+LG P D+ ++ + G +D + + Sbjct: 30 GKLVGFDIDLAK-AIAKKLGVKVEFKPMDFDG----IIPALQSGKIDVVIAGMTITEERK 84 Query: 278 ASLLCCHEA--CGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVAD 335 + G +++V N SI + L G+ G G + Sbjct: 85 KQVDFSDPYFEAGQAIVV----KKGNDSIKSLEDLKGKKV-GVQLGSTSEQH-------- 131 Query: 336 FMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLT 374 KK + DA + + F+ +E F L+SG+ V Sbjct: 132 --VKKVAKDAGV-KVKKFDNFSEAFQELKSGRVDAVVTD 167 >6DHM-A nrPDB Length = 582 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 18/41 (43%), Gaps = 3/41 (7%) Query: 189 KVTPG---STCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 +TPG T AV G G VGL + GA + + + Sbjct: 318 GMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESD 358 >4RDI-A nrPDB Length = 288 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 18/54 (33%) Query: 177 FSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKF 230 T K ++ + V G+GGVG G I +D++ Sbjct: 34 GGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCV 87 >5IJZ-A nrPDB Length = 447 Score = 28.1 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 12/34 (35%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDIN 226 G V G G V + + GA I D + Sbjct: 233 GQKIIVSGSGNVATYAIEKAQELGATVIGFSDSS 266 >2LDB-A nrPDB Length = 317 Score = 28.1 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAG-AARIIAVDINKDK 229 G+ V G G VG S V G A I+ +D N+ K Sbjct: 6 GARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESK 43 >3T5Y-A nrPDB Length = 357 Score = 28.1 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 11/24 (45%) Query: 180 GYGSAVKVAKVTPGSTCAVFGLGG 203 G V+ A V PG +FG G Sbjct: 304 GLAHLVENALVQPGDRVLLFGGGA 327 >1ZEJ-A nrPDB Length = 293 Score = 28.1 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 25/62 (40%), Gaps = 6/62 (9%) Query: 195 TCAVFGLGGVG-LSVVMGC-KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 V G G +G + K ++ D+++ A+E E ++ ++ ++ Sbjct: 14 KVFVIGAGLMGRGIAIAIASKH----EVVLQDVSEKALEAAREQIPEELLSKIEFTTTLE 69 Query: 253 EV 254 +V Sbjct: 70 KV 71 >1V9C-A nrPDB Length = 218 Score = 27.7 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 38/108 (35%), Gaps = 10/108 (9%) Query: 205 GLSVVM-GCKAAGAARIIAVDINKDKFAK----AKELGATECINPQDYKKP----IQEVL 255 GL + G + AR+IA +N ++ EL A + + V Sbjct: 59 GLKAIQAGARILVDARMIACGLNPERLRLFGNEVVELLAHPEVVARAKATGGTRAEAAVA 118 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV-GVPPDSQNL 302 G +D + +G T + +L+ +V G+P N+ Sbjct: 119 YAWEKGLLDGAIVGVGNAPTFLLALVEAIRQGARPALVLGMPVGFVNV 166 >4PRK-A nrPDB Length = 336 Score = 27.7 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDI 225 T + G+G +G +V A GA +++A D+ Sbjct: 147 KTIGLIGVGHIGSAVAQIFSAMGA-KVLAYDV 177 >5B37-A nrPDB Length = 361 Score = 27.7 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 7/74 (9%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARI--IAVDINKDKFAKAKEL-GATECINPQDYKK 249 G AV GLG VG + C+ + D++ K + K L GAT + P + Sbjct: 169 GMKVAVQGLGNVGKN---LCRHLHEHDVQLFVSDVDPIKAEEVKRLFGAT-VVEPTEIYS 224 Query: 250 PIQEVLKEMTDGGV 263 ++ GG+ Sbjct: 225 LDVDIFAPCALGGI 238 >3GG9-A nrPDB Length = 352 Score = 27.7 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%) Query: 178 STGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA 233 ST + +V G T +FG G +G V +A G ++ N + A+A Sbjct: 145 STTMPPNFGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARA 200 >2GMH-A nrPDB Length = 584 Score = 27.7 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT----ECINPQDYKK 249 + G G GLS K A D+ KA +GA C++P+ +++ Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQH--EKDLRVCLVEKAAHIGAHTLSGACLDPRAFEE 93 >5EES-A nrPDB Length = 247 Score = 27.7 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 45/145 (31%), Gaps = 15/145 (10%) Query: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFS 266 V+G K I+A D E+G + L + D G + Sbjct: 4 VGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDD-------------DLSLLVDNGAEVV 50 Query: 267 FEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSK 326 + + +M +L C G S +VG L G+ G + + Sbjct: 51 VDFT-TPNAVMGNLEFCIN-NGISAVVGTTGFDDARLEQVRDWLEGKDNVGVLIAPNFAI 108 Query: 327 ESVPKLVADFMAKKFSLDALITNIL 351 +V +V A +F A + + Sbjct: 109 SAVLTMVFSKQAARFFESAEVIELH 133 >3OJO-A nrPDB Length = 431 Score = 27.7 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 193 GSTCAVFGLGGVGL-SVVMGCKAAGAARIIAVDIN 226 GS V GLG +GL + +M K ++ VDIN Sbjct: 11 GSKLTVVGLGYIGLPTSIMFAKH--GVDVLGVDIN 43 >4MIE-A nrPDB Length = 351 Score = 27.7 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 31/92 (33%), Gaps = 12/92 (13%) Query: 195 TCAVFGLGGVGLSVV--MGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 V G G +G + + + GA + DI+ + A +N + Y Sbjct: 16 KVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVR---DFHLNAKVYPDD-- 70 Query: 253 EVLKEMTDGGVDFSFEVI---GRLDTMMASLL 281 + D +D F V T++ +L Sbjct: 71 --TSLLQDPDIDAVFVVSFGGAHEATVLKALD 100 >2YY8-A nrPDB Length = 201 Score = 27.7 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 35/100 (35%), Gaps = 8/100 (8%) Query: 208 VVMGCKAAGAARIIAVDINKDKF-----AKAKELGATECINPQDYKKPIQEVLKEMTDGG 262 V + +A GA II +K K G I ++ + ++V+KE T Sbjct: 21 VALTARAFGADGIIIASEEDEKVKESVEDVVKRWGGPFFI---EFNRNWRKVMKEFTGVK 77 Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 V + + D + + +IVG + + Sbjct: 78 VHLTMYGLHVDDVIEELKEKLKKGEDFMIIVGAEKVPREV 117 >4L4S-H nrPDB Length = 339 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 191 TPGSTCAVFGLGGVGLS-VVMGCKAAGAARIIAVDINKDKFA 231 TP + V G+G VG++ + A + VD+ +DK Sbjct: 17 TPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLK 58 >4GBJ-A nrPDB Length = 297 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 34/102 (33%), Gaps = 11/102 (10%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 A GLG +G + AG ++ + K +LGAT N D Sbjct: 6 EKIAFLGLGNLGTPIAEILLEAG-YELVVWNRTASKAEPLTKLGATVVENAIDA------ 58 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 +T GG+ FS + S+ + V V + Sbjct: 59 ----ITPGGIVFSVLADDAAVEELFSMELVEKLGKDGVHVSM 96 >1BG6-A nrPDB Length = 359 Score = 27.3 bits (59), Expect = 9.7, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 42/119 (35%), Gaps = 5/119 (4%) Query: 194 STCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 T AV GLG G + G + ++A DI+ + + ++ GA P + Sbjct: 5 KTYAVLGLGNGGHAFAAYLALKGQS-VLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPD 63 Query: 254 VLKE---MTDGGVDFSFEVIGRLDTMMASL-LCCHEACGTSVIVGVPPDSQNLSINPML 308 +L + D V+ + + + + + G +I+ L +L Sbjct: 64 LLTSDIGLAVKDADVILIVVPAIHHASIAANIASYISEGQLIILNPGATGGALEFRKIL 122 >5JFC-L nrPDB Length = 474 Score = 27.3 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 10/29 (34%) Query: 193 GSTCAVFGLGGVGLSVVMGCKAAGAARII 221 G A+ G G GL+ G I Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTI 182 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.133 0.367 Lambda K H 0.267 0.0408 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,501,865 Number of Sequences: 36641 Number of extensions: 621933 Number of successful extensions: 3678 Number of sequences better than 10.0: 380 Number of HSP's better than 10.0 without gapping: 312 Number of HSP's successfully gapped in prelim test: 186 Number of HSP's that attempted gapping in prelim test: 2690 Number of HSP's gapped (non-prelim): 588 length of query: 375 length of database: 10,336,785 effective HSP length: 99 effective length of query: 276 effective length of database: 6,709,326 effective search space: 1851773976 effective search space used: 1851773976 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.7 bits)