BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P00325 (375 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1HSZ-A nrPDB 762 0.0 1U3W-A nrPDB 729 0.0 1HSO-A nrPDB 720 0.0 1EE2-A nrPDB 666 0.0 1D1T-A nrPDB 555 e-158 1MC5-A nrPDB 478 e-135 3COS-A nrPDB 465 e-131 1P0F-A nrPDB 444 e-125 1CDO-A nrPDB 430 e-121 1E3E-A nrPDB 416 e-116 4DLA-A nrPDB 409 e-114 4JJI-A nrPDB 402 e-113 4RQU-A nrPDB 394 e-110 5TNX-A nrPDB 207 5e-54 1F8F-A nrPDB 190 7e-49 3PII-A nrPDB 130 6e-31 5YLN-A nrPDB 122 3e-28 4Z6K-A nrPDB 118 3e-27 3MEQ-A nrPDB 115 4e-26 4CPD-A nrPDB 109 2e-24 3S2F-A nrPDB 105 3e-23 1LLU-A nrPDB 104 5e-23 4EEZ-A nrPDB 104 6e-23 1H2B-A nrPDB 104 8e-23 2DFV-A nrPDB 101 4e-22 2EER-A nrPDB 101 4e-22 5VM2-A nrPDB 101 6e-22 6FG0-A nrPDB 100 8e-22 6N7L-A nrPDB 99 4e-21 2DQ4-A nrPDB 96 3e-20 3GFB-A nrPDB 95 4e-20 1PL8-A nrPDB 94 1e-19 4GKV-A nrPDB 93 1e-19 3QE3-A nrPDB 92 4e-19 4EJ6-A nrPDB 92 4e-19 2H6E-A nrPDB 91 6e-19 5ENV-A nrPDB 91 7e-19 1R37-A nrPDB 89 3e-18 1YKF-A nrPDB 89 3e-18 3TWO-A nrPDB 88 5e-18 3FPL-A nrPDB 88 6e-18 5K1S-A nrPDB 88 7e-18 4UEJ-A nrPDB 87 2e-17 5KIA-A nrPDB 85 4e-17 4ILK-A nrPDB 84 8e-17 4OH1-A nrPDB 84 1e-16 5YAT-A nrPDB 82 5e-16 4JLW-A nrPDB 81 9e-16 1KEV-A nrPDB 76 3e-14 3FPC-A nrPDB 75 4e-14 3FSR-A nrPDB 74 8e-14 3WLE-A nrPDB 73 2e-13 1KOL-A nrPDB 72 4e-13 2DPH-A nrPDB 71 6e-13 5VKT-A nrPDB 70 1e-12 1UUF-A nrPDB 69 3e-12 3IP1-A nrPDB 68 8e-12 2OUI-A nrPDB 67 1e-11 5Z0C-A nrPDB 67 1e-11 5H82-A nrPDB 67 2e-11 1E3J-A nrPDB 66 2e-11 3UOG-A nrPDB 63 2e-10 4OAQ-A nrPDB 62 3e-10 6DKH-A nrPDB 62 4e-10 3M6I-A nrPDB 61 1e-09 2VCY-A nrPDB 60 2e-09 5FI5-A nrPDB 59 4e-09 1YQX-A nrPDB 57 2e-08 1WLY-A nrPDB 55 6e-08 2CDC-A nrPDB 54 1e-07 3QWB-A nrPDB 53 2e-07 1YB5-A nrPDB 53 2e-07 1QOR-A nrPDB 50 1e-06 5H83-A nrPDB 49 3e-06 3JYN-A nrPDB 47 1e-05 3B70-A nrPDB 46 3e-05 3WID-A nrPDB 45 4e-05 3SLK-A nrPDB 44 8e-05 1Q1N-A nrPDB 44 1e-04 4A27-A nrPDB 44 1e-04 3FBG-A nrPDB 41 0.001 4RVS-A nrPDB 40 0.002 2WEK-A nrPDB 39 0.004 4Y1B-A nrPDB 37 0.010 3HZZ-A nrPDB 37 0.013 4DVJ-A nrPDB 36 0.025 6C49-A nrPDB 36 0.028 4IDE-A nrPDB 35 0.037 3TQH-A nrPDB 35 0.057 2OBY-A nrPDB 34 0.11 4J6F-A nrPDB 33 0.15 5A3V-A nrPDB 33 0.21 2VWH-A nrPDB 31 1.0 2CF5-A nrPDB 31 1.1 4KPA-A nrPDB 30 1.4 6ACF-A nrPDB 30 1.6 2VN8-A nrPDB 30 1.7 1JGT-A nrPDB 29 3.4 1V9L-A nrPDB 29 4.1 5ILO-A nrPDB 28 4.5 2B25-A nrPDB 28 5.9 1V3V-A nrPDB 28 7.0 1NBW-A nrPDB 28 8.4 4A10-A nrPDB 28 9.4 >1HSZ-A nrPDB Length = 374 Score = 762 bits (1968), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 300 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTVLTF 375 LLHSGKSIRTVLTF Sbjct: 361 LLHSGKSIRTVLTF 374 >1U3W-A nrPDB Length = 374 Score = 729 bits (1882), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/374 (94%), Positives = 366/374 (97%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVA GICR+D+HVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR+CKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTC GKPIHHF+G STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS VMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIG+LDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSINPMLLLTGRTWKGA++GGFKSKE +PKLVADFMAKKFSLDALIT+VLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTVLTF 375 LL SGKSIRTVLTF Sbjct: 361 LLRSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 720 bits (1858), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/374 (93%), Positives = 362/374 (96%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVAVGIC TDDHVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCR+CKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 120 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTCR KPIHHFLG STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSA+MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLLTGRTWKGA+ GGFKSKE +PKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTVLTF 375 LLHSGKSIRT+L F Sbjct: 361 LLHSGKSIRTILMF 374 >1EE2-A nrPDB Length = 373 Score = 666 bits (1718), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/374 (86%), Positives = 347/374 (92%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWE KKPFSIE+VEVAPPKA+EVRIKMVA GICR+DDHVVSG LV P Sbjct: 1 STAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVI GHEAAGIVES+GEGVTTV+PGDKVIPLF PQCGKC VCK+PE N CLKN L PR Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKN-LSMPR 119 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GT+QDGT RFTCRGKPIHHFLGTSTFSQYTVVDE +VAKIDAASPLEKVCL+GCGFSTGY Sbjct: 120 GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY 179 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVT GSTCAVFGLGGVGLS +MGCKAAGAARII VDINKDKFAKAKE+GATEC Sbjct: 180 GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 +NPQDYKKPIQEVL EM++GGVDFSFEVIGRLDTM+A+L CC EA G SVIVGVPP SQN Sbjct: 240 VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN 299 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLL+GRTWKGA++GGFKSK+ +PKLVADFMAKKF+LD LITHVLPFEKINEGFD Sbjct: 300 LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD 359 Query: 362 LLHSGKSIRTVLTF 375 LL SGKSIRT+LTF Sbjct: 360 LLRSGKSIRTILTF 373 >1D1T-A nrPDB Length = 373 Score = 555 bits (1429), Expect = e-158, Method: Compositional matrix adjust. Identities = 260/373 (69%), Positives = 315/373 (84%), Gaps = 1/373 (0%) Query: 3 TAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL 62 TAGKVIKCKAAVLWE K+PFSIE++EVAPPK EVRIK++A GICRTDDHV+ G +V+ Sbjct: 2 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG 122 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ RG Sbjct: 62 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 120 Query: 123 TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 L DGT RFTC+GKP+HHFL TSTF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 121 VLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 180 Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AV KV PGSTC VFGLGGVGLS +MGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 181 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 240 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP+++ L Sbjct: 241 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 300 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 + +PMLL TGRTWKG V+GG KS++ +PKLV +F+AKKF LD LITHVLPF+KI+EGF+L Sbjct: 301 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 360 Query: 363 LHSGKSIRTVLTF 375 L+SG+SIRTVLTF Sbjct: 361 LNSGQSIRTVLTF 373 >1MC5-A nrPDB Length = 374 Score = 478 bits (1229), Expect = e-135, Method: Compositional matrix adjust. Identities = 233/371 (62%), Positives = 293/371 (78%), Gaps = 1/371 (0%) Query: 4 AGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG-NLVTPL 62 A +VIKCKAAV WE KP SIE++EVAPPKA+EVRIK++A +C TD + +SG + Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG 122 PVILGHE AGIVESVGEGVT +K GD VIPL+ PQCG+C+ C NP++N C K + +G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 123 TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + DGT RFTC+GK I H++GTSTFS+YTVV + +VAKID +PL+KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AVN AK+ PGS CAVFGLGGVGL+ +MGCK AGA+RII VDINKDKFA+AKE GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 NPQD+ KPIQEVL EMTDGGVD+SFE IG + M A+L CH+ G SV+VGV + + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 + P L+TGRTWKG +GG+KS E +PKLV+++M+KK +D +TH L F++IN+ F+L Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 363 LHSGKSIRTVL 373 +HSGKSIRTV+ Sbjct: 362 MHSGKSIRTVV 372 >3COS-A nrPDB Length = 381 Score = 465 bits (1196), Expect = e-131, Method: Compositional matrix adjust. Identities = 229/380 (60%), Positives = 288/380 (75%), Gaps = 5/380 (1%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV- 59 M T GKVIKCKAA+ WE KP IE+VEVAPPKA+EVRI+++A +C TD V+ Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 60 TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLK-NDLG 118 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K ++L Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 119 NP---RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 +P + ++D T RFTC+GKP++HF GTSTFSQYTVV + +AKID + LE+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 GFSTGYG+A+N AKVTPGSTCAVFGLGGVGLSAVMGCKAAGA+RII +DIN +KF KAK Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 296 PPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEK 355 S+ L++ P L+ GRT G +GG+KS + IPKLV D+ KKF+LDAL+TH LPF+K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 356 INEGFDLLHSGKSIRTVLTF 375 I+E FDL++ GKSIRT+L F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1P0F-A nrPDB Length = 373 Score = 444 bits (1142), Expect = e-125, Method: Compositional matrix adjust. Identities = 221/375 (58%), Positives = 290/375 (77%), Gaps = 2/375 (0%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVT 60 M TAGK I CKAAV WE KP S+E + VAPPKA+EVRIK++A GIC +D V+ + + Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 PVILGHEA G+VES+G GVT VKPGDKVIPLF PQCG CR CK+ SN+C KND+G Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + D T RFTCRGKPI++ +GTSTF++YTVV + AVAKID +PLE CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AVN AKVTPGSTCAVFGLGGVG SA++GCKAAGA+RII V +KDKF KA ELGATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 C+NP+DY KPI EV+ E T+GGVD++ E GR++TMM +L + G +V++G+ ++ Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 L ++P+LLLTGR+ KG+V+GGFK +E + +LV D+M KK +++ L++ L ++IN+ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKGEE-VSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 361 DLLHSGKSIRTVLTF 375 +LL SG+ +R+++ + Sbjct: 359 ELLSSGQGVRSIMIY 373 >1CDO-A nrPDB Length = 374 Score = 430 bits (1105), Expect = e-121, Method: Compositional matrix adjust. Identities = 208/375 (55%), Positives = 270/375 (72%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTD-DHVVSGNLVT 60 +T GKVIKCKAAV WE KP IE++EV P A E+RIK++A G+C TD H+ G Sbjct: 1 ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 PV+LGHE AGIVESVG GVT +PG+KVIPLF QCG+CR C++P++N C+K Sbjct: 61 GFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANES 120 Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 + RFTC+G+ + FLGTSTFSQYTVV++ AVAKID ++PL+ VCL+GCG STG Sbjct: 121 PDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTG 180 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +G+AVN AKV PGSTCAVFGLG VGL+AVMGC +AGA RIIAVD+N DKF KAK GAT+ Sbjct: 181 FGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATD 240 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 +NP D+ +PI +VL +MT+GGVDFS E +G + M +L C + G SV+VG Sbjct: 241 FVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDL-H 299 Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 +++ P+ L+ GRTWKG+++GGFK K+G+PK+V ++ KK LD ITH +P E +N+ Sbjct: 300 DVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAI 359 Query: 361 DLLHSGKSIRTVLTF 375 DL+ GK IRTVL+ Sbjct: 360 DLMKHGKCIRTVLSL 374 >1E3E-A nrPDB Length = 376 Score = 416 bits (1068), Expect = e-116, Method: Compositional matrix adjust. Identities = 202/377 (53%), Positives = 271/377 (71%), Gaps = 6/377 (1%) Query: 3 TAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL 62 T GKVIKCKAA+ W+ P IE++EV+PPKA EVRI+++A +C TD + Sbjct: 2 TQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKALF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLK-NDLGNP- 120 PV+LGHE AGIVESVG GVT KPGDKVIP F PQC +C++C +P +N C K + P Sbjct: 62 PVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPT 121 Query: 121 --RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFS 178 + ++D T RFTC+G+ I+HF+G S+FSQYTVV E +A++D + LE+VCLIGCGFS Sbjct: 122 IDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFS 181 Query: 179 TGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGA 238 +GYG+A+N AKVTPGSTCAVFGLG VGLSA++GCK AGA+RIIA+DIN +KF KAK LGA Sbjct: 182 SGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGA 241 Query: 239 TECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPA 298 T+C+NP++ KP+Q+V+ E+T GGVD+S + G T+ A++ C G+ +VG Sbjct: 242 TDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGA--K 299 Query: 299 SQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINE 358 ++I + ++ GR+ G +GG+KS + +P LV+D+ KKF LD L+TH LPFE IN+ Sbjct: 300 VDEMTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIND 359 Query: 359 GFDLLHSGKSIRTVLTF 375 DL+ GKSIRT+LTF Sbjct: 360 AIDLMKEGKSIRTILTF 376 >4DLA-A nrPDB Length = 396 Score = 409 bits (1051), Expect = e-114, Method: Compositional matrix adjust. Identities = 201/374 (53%), Positives = 261/374 (69%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 +T G+VI CKAAV WE KP IEDV+VAPP+A EVR+K++ +C TD + SG Sbjct: 19 ATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEG 78 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 L P +LGHEAAGIVESVGEGVT V+PGD VIP + +C +C+ CK+ ++N C K Sbjct: 79 LFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATG 138 Query: 121 RGTL-QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ GKPI+HF+GTSTFSQYTVV + +VAKID +PLEKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS AVFGLG VGL+ G KAAGA+RII +DI+ KF +AK G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 E INP+++++PIQ+V+ ++TDGGVD+SFE IG + M ++L CCH+ GTSVIVGV + Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG +GGFKS+ +P LV ++ K+ +D ITH + IN+ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 360 FDLLHSGKSIRTVL 373 FDL+H G +R VL Sbjct: 379 FDLMHDGDCLRVVL 392 >4JJI-A nrPDB Length = 378 Score = 402 bits (1034), Expect = e-113, Method: Compositional matrix adjust. Identities = 202/374 (54%), Positives = 258/374 (68%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 +T G+VI CKAAV +E KP IEDV+VAPP+A EVRIK++ +C TD + SG Sbjct: 1 ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 60 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 L P ILGHEAAGIVESVGEGVT V+ GD VIP + +C +C+ CK+ ++N C K Sbjct: 61 LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 120 Query: 121 RG-TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ GKPI+HF+GTSTFSQYTVV + +VAKID +PL+KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS A+FGLG VGL+ G K AGA+RII +DI+ K+ AK+ G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 E +NP+D+ KPIQEV+ ++TDGGVD+SFE IG + M A+L CCH+ GTSVIVGV + Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG +GGFKS+ +P LV +M K+ +D ITH L +IN+ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 360 FDLLHSGKSIRTVL 373 FDLLH G +R VL Sbjct: 361 FDLLHEGTCLRCVL 374 >4RQU-A nrPDB Length = 375 Score = 394 bits (1012), Expect = e-110, Method: Compositional matrix adjust. Identities = 190/372 (51%), Positives = 250/372 (67%), Gaps = 2/372 (0%) Query: 6 KVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL-PV 64 ++I+CKAAV WE KP IE+VEVAPP+ +EVRIK++ +C TD + TPL P Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG-T 123 I GHEA GIVESVGEGVT ++PGD V+P+FT +CG+CR C + ESN C + RG Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + DG RF+ GKPI+HFLGTSTFS+YTVV VAKI+ +PL+KVC++ CG STG G+ Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 +NVAK G + A+FGLG VGL A G + AGA+RII VD N +F +AKE G TEC+N Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLS 303 P+D+ KPIQ+V+ EMTDGGVD S E G + M+ + C H+ G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 304 INPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 +PM L RT KG +G +K K IP +V +M K+ L+ ITH +PF +IN+ FD + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 364 HSGKSIRTVLTF 375 G+SIR ++T Sbjct: 362 LKGESIRCIITM 373 >5TNX-A nrPDB Length = 383 Score = 207 bits (527), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 134/357 (37%), Positives = 189/357 (52%), Gaps = 10/357 (2%) Query: 21 PFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEG 80 PFSIE + P+ EV +++VA G+C TD V PLP +LGHE AG+VE+VG Sbjct: 29 PFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVGPN 88 Query: 81 VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG-TRRFTCRGKPIH 139 V T+ GD V+ L CG C C YC + N G DG T G+P+H Sbjct: 89 VKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEPLH 147 Query: 140 -HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAV 198 HF S+F+ Y + EN K+ +PLE + +GCG TG G+ +N V GS+ A Sbjct: 148 DHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSFAS 207 Query: 199 FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 FG G VG+SAVM + AGA IIAVDI + A A ELGAT IN ++ + + ++E+ Sbjct: 208 FGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIREI 265 Query: 259 TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--ASQNLSINPMLLLTGRTWK 316 T GGVD++ E G L +++ + + GT +VG P +N LLL G T + Sbjct: 266 TGGGVDYALESTG-LPAVLSQGIDALGSRGTMGVVGAPKLGTKAEFDVNS-LLLGGHTIR 323 Query: 317 GAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVL 373 G V G + IP+LV + +F D L+ P E+IN+ SG +++ +L Sbjct: 324 GIVEGDSVPQTFIPQLVQLHLQGRFPFDRLVK-FYPLEQINQAAADSSSGITLKPIL 379 >1F8F-A nrPDB Length = 371 Score = 190 bits (483), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 121/341 (35%), Positives = 180/341 (52%), Gaps = 10/341 (2%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGV 81 F ++ +++ P+ EV +K+VA G+C TD V PLP +LGHE +GI+E++G V Sbjct: 19 FELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGSGIIEAIGPNV 78 Query: 82 TTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPI--H 139 T ++ GD V+ L CGKC C YC + N G +G + + Sbjct: 79 TELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQGVVND 137 Query: 140 HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF 199 HF S+F+ Y + EN K+ P+E + +GCG TG G+ +N KVTP S+ + Sbjct: 138 HFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALKVTPASSFVTW 197 Query: 200 GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G G VGLSA++ K GA+ IIAVDI + + AK+LGAT IN + + P+ + KE+T Sbjct: 198 GAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKT-QDPVAAI-KEIT 255 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--ASQNLSINPMLLLTGRTWKG 317 DGGV+F+ E G + + + G +VG P + +N LLL G+T G Sbjct: 256 DGGVNFALESTGSPEILKQGVDALG-ILGKIAVVGAPQLGTTAQFDVND-LLLGGKTILG 313 Query: 318 AVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINE 358 V G K+ IP+LV + KF D L+ F++IN+ Sbjct: 314 VVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQ 353 >3PII-A nrPDB Length = 339 Score = 130 bits (328), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 124/370 (33%), Positives = 170/370 (45%), Gaps = 40/370 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAY-EVRIKMVAVGICRTDDHVVSGNL-VTP-LPVILG 67 KAAV+ + K+P I++VE P +Y EV +++ A G+C TD H G+ V P LP+I G Sbjct: 2 KAAVVEQFKEPLKIKEVE-KPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPG 60 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 HE GIVE VG GVT +K GD+V IP CG C C + + C + G D Sbjct: 61 HEGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLC---EHQKNAGYSVD 117 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G +++Y + V KI E+ I C T Y A+ Sbjct: 118 G------------------GYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALK 158 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 V PG A++G+GG G AV KA G ++AVDI +K AKELGA +NP Sbjct: 159 VTGAKPGEWVAIYGIGGFGHVAVQYAKAMG-LNVVAVDIGDEKLELAKELGADLVVNP-- 215 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 K+ + +KE GGV + V S G V+VG+PP + I Sbjct: 216 LKEDAAKFMKEKV-GGVHAAV-VTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFD 273 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +L G G++ G K + + A+ K I V P EKINE FD + G Sbjct: 274 T-VLNGIKIIGSIVGTRKDLQEALQFAAEGKVKT------IIEVQPLEKINEVFDRMLKG 326 Query: 367 K-SIRTVLTF 375 + + R VLT Sbjct: 327 QINGRVVLTL 336 >5YLN-A nrPDB Length = 356 Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 106/353 (30%), Positives = 163/353 (46%), Gaps = 37/353 (10%) Query: 20 KPFSIEDVEVAPP---KAYEVRIKMVAVGICRTDDHVVSGNLVT-PLPVILGHEAAGIVE 75 KP V+V P K + +++V IC TD H++ G++ T ILGHE GIVE Sbjct: 12 KPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEGIGIVE 71 Query: 76 SVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRG 135 VGEGV+ K GDKV+ CGKC CK +C +++ G G L DG + R Sbjct: 72 EVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHC-EDEGGWIFGHLIDGMQAEYLR- 129 Query: 136 KPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195 + H T + + DE V D TGY V KV PG + Sbjct: 130 --VPHADNTLYHTPEDLSDEALVMLSDI-------------LPTGYEIGVLKGKVEPGCS 174 Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 A+ G G VGL+A++ + A++I VD++ ++ A GAT +N D +K I+E+ Sbjct: 175 VAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKEIY 234 Query: 256 KEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN--PMLLLTG 312 ++TDG GVD + E +G + A+ C + I+GV N ++ P+ Sbjct: 235 -DLTDGRGVDVAIEAVG----IPATFDFCQK------IIGVDGTVANCGVHGKPVEFDLD 283 Query: 313 RTW--KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 + W V G S P+L+ + K + L+TH +I + +++ Sbjct: 284 KLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVF 336 >4Z6K-A nrPDB Length = 346 Score = 118 bits (296), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 110/361 (30%), Positives = 164/361 (45%), Gaps = 39/361 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPL-PVILGH 68 KAAVL E + IE+V++ P A E+ +KM A G+C TD H V G+ V P P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E G++ +VGEGVT VK GD+V + CG C +CL G Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHC--------THCL-------------G 100 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 C + + +F++Y + + N V I + ++ + C T Y + + Sbjct: 101 GWETLCESQQNSGYSVNGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKM 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G AV A G + AVDI+ DK A AK+LGA +N ++ Sbjct: 160 TDTKPGDWVVISGIGGLGHMAVQYAIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKN- 217 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 P + + KE+ V + S+L GT V G+PP +SI Sbjct: 218 TDPAEYLQKEIGGAHGALVTAVSAKAFDQALSML---RRGGTLVCNGLPPGDFPVSIFDT 274 Query: 308 LLLTGRTWKGAVYGG-FKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +L G T +G++ G +E + MA + A +T P E IN+ F+ + G Sbjct: 275 -VLNGITIRGSIVGTRLDLQESLD------MAAAGKVKATVT-AEPLENINDIFERMRQG 326 Query: 367 K 367 K Sbjct: 327 K 327 >3MEQ-A nrPDB Length = 365 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 108/360 (30%), Positives = 150/360 (41%), Gaps = 35/360 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTP-LPVILGH 68 KAAV+ KP +I++V + P ++++ + A G+C TD H G+ V P P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GV VK GD+V IP CG CR C C + L G Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQ--------LNTG 138 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 ++ G F++Y V D N V + ++ + C T Y + V Sbjct: 139 ---YSVNGG----------FAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGLKV 184 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G AV +A G + AVDI+ K A+ LGAT +N + Sbjct: 185 TDTKPGDWVVISGIGGLGHMAVQYARAMGL-NVAAVDIDDRKLDLARRLGATVTVNAKTV 243 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 P + KE TDGG V L GT + G+PP LSI M Sbjct: 244 ADPAAYIRKE-TDGGAQGVL-VTAVSPKAFEQALGMVARGGTVSLNGLPPGDFPLSIFNM 301 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G T +G++ G + AD K E IN FD + G Sbjct: 302 -VLNGVTVRGSIVGTRLDLQESLDFAADGKVKA------TIQTGKLEDINAIFDDMRQGN 354 >4CPD-A nrPDB Length = 347 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 100/369 (27%), Positives = 165/369 (44%), Gaps = 34/369 (9%) Query: 13 AVLWEVKKPFSIEDV---EVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHE 69 AV++E K+ ++++V + P VR+ + GIC +D H+ G + +LGHE Sbjct: 3 AVVFENKERVAVKEVNAPRLQHPLDALVRVHLA--GICGSDLHLYHGKIPVLPGSVLGHE 60 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDL---GNPRGTLQD 126 G VE+VGEG+ ++PGD V+ F CG C C+ + N C + + G G LQ Sbjct: 61 FVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQ- 119 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G + R FS + K+ E+ G ST YG + Sbjct: 120 GAQAEILR----------VPFSNVNL------RKLPPNLSPERAIFAGDILSTAYGGLIQ 163 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 ++ PG + AV G G VGL A+ + GA++I+A+D ++ +A LGA IN + Sbjct: 164 -GQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQ 221 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 + P++ V E D G D E +G T+ +L G VGV N P Sbjct: 222 -ENPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPG-GRVSAVGV----DNAPSFP 275 Query: 307 MLLLTGRTWKGAVYGGFKSKE-GIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 L +G G + I ++A + + + +++H LP E+ G++L Sbjct: 276 FPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDR 335 Query: 366 GKSIRTVLT 374 ++++ +L Sbjct: 336 KEALKVLLV 344 >3S2F-A nrPDB Length = 340 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 107/369 (28%), Positives = 158/369 (42%), Gaps = 38/369 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTP-LPVILGH 68 KAAV+ P +I++V V P +V++K+ A G+C TD H G+ V P LP I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GV+ VK GD+V +P CG C C C K Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQ----------- 112 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 ++ G + +Y V D N V + ++ I C T Y + V Sbjct: 113 NTGYSVNGG----------YGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKV 161 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G AV +A G R+ AVDI+ K A+ LGA +N +D Sbjct: 162 TDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARD- 219 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 P + KE+ G V + + GT + G+PP I Sbjct: 220 TDPAAWLQKEI---GGAHGVLVTAVSPKAFSQAIGMVRRGGTIALNGLPPGDFGTPIFD- 275 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 ++L G T +G++ G ++ + + + DF A + T L + +N+ F L GK Sbjct: 276 VVLKGITIRGSIVG---TRSDLQESL-DFAAHGDVKATVSTAKL--DDVNDVFGRLREGK 329 Query: 368 -SIRTVLTF 375 R VL F Sbjct: 330 VEGRVVLDF 338 >1LLU-A nrPDB Length = 342 Score = 104 bits (260), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 83/290 (28%), Positives = 128/290 (44%), Gaps = 30/290 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN--LVTPLPVILGH 68 KAAV+ P IE+V+V P +V +K+ A G+C TD H G+ + PLP I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GVT VK GD+V IP CG C C C Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQ----------- 116 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 ++ G +++Y + D N V + ++ I C T Y + Sbjct: 117 NTGYSVNGG----------YAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGLKQ 165 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A+ G+GG+G AV +A G + A+DI+ K A++LGA+ +N + Sbjct: 166 TNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVNARQ- 223 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 + P++ + +++ G V ++ + GT +VG+PP Sbjct: 224 EDPVEAIQRDI---GGAHGVLVTAVSNSAFGQAIGMARRGGTIALVGLPP 270 >4EEZ-A nrPDB Length = 348 Score = 104 bits (260), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 105/359 (29%), Positives = 158/359 (44%), Gaps = 51/359 (14%) Query: 28 EVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPG 87 E+ K E + M G+C TD HV +G+ +LGHE GIV+ +G V++++ G Sbjct: 20 ELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHEGIGIVKEIGADVSSLQVG 79 Query: 88 DKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTST 146 D+V + F CG C C + +C R G + + Sbjct: 80 DRVSVAWFFEGCGHCEYCVSGNETFC----------------REVKNAGYSVDGGMA--- 120 Query: 147 FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGL 206 + VV + AV D P+E I C T Y A+ V+ V PG +FG GG+G Sbjct: 121 -EEAIVVADYAVKVPDGLDPIE-ASSITCAGVTTY-KAIKVSGVKPGDWQVIFGAGGLGN 177 Query: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDF 265 A+ K A++IAVDIN+DK AK++GA IN D P+ E+ K++T G GV Sbjct: 178 LAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDV-NPVDEI-KKITGGLGVQS 235 Query: 266 SFE-VIGRL--DTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGG 322 + + R+ + +ASL + G V V VP LS+ P ++ G G++ G Sbjct: 236 AIVCAVARIAFEQAVASL----KPMGKMVAVAVPNTEMTLSV-PTVVFDGVEVAGSLVGT 290 Query: 323 FKSKEGIPKLVADFMAKKFSLDAL-----ITHVLPFEKINEGFDLLHSGK-SIRTVLTF 375 +A+ F A I E+IN+ D + +GK R V+ F Sbjct: 291 RLD-----------LAEAFQFGAEGKVKPIVATRKLEEINDIIDEMKAGKIEGRMVIDF 338 >1H2B-A nrPDB Length = 359 Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 83/272 (30%), Positives = 134/272 (49%), Gaps = 28/272 (10%) Query: 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKA-YEVRIKMVAVGICRTDDHVVSG---NLVTP- 61 V + KAA L E KP IEDV+ + ++V +++ G+C TD H+V G L+ P Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LP LGHE G +E V EGV ++ GD VI G C C+ E +C +L P Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHC--ENLEFPG 130 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 + G F+ TS S + + + K+ +PL + T Y Sbjct: 131 LNIDGG----------FAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGI------TAY 174 Query: 182 GSAVNVAK-VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 + A+ + PG+ A+ G+GG+G AV K A +IA+D+ ++K A+ LGA Sbjct: 175 RAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLGADH 234 Query: 241 CINPQDYKKPIQEVLKEMTDG-GVDFSFEVIG 271 ++ + + P+++V+ E+T G GV+ + + +G Sbjct: 235 VVDAR--RDPVKQVM-ELTRGRGVNVAMDFVG 263 >2DFV-A nrPDB Length = 347 Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 100/361 (27%), Positives = 158/361 (43%), Gaps = 45/361 (12%) Query: 26 DVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN-----LVTPLPVILGHEAAGIVESVGEG 80 +V+V P EV IK++A IC TD H+ N + P P I+GHE AG V +G G Sbjct: 20 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP-PQIMGHEVAGEVVEIGPG 78 Query: 81 VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHH 140 V ++ GD V CGKC C+ + + C + G DG Sbjct: 79 VEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKI---FGVDTDG------------- 122 Query: 141 FLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP--GSTCAV 198 F++Y VV + K + P E L G+AV+ P G + + Sbjct: 123 -----VFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPISGKSVLI 172 Query: 199 FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G G +GL + KA+GA +I + + + AK++GA INP +++ + + + ++ Sbjct: 173 TGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINP--FEEDVVKEVMDI 230 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKG 317 TDG GVD E G + L A G ++G+ P + N +++ T Sbjct: 231 TDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTIDFNNLIIFKALT--- 286 Query: 318 AVYG--GFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSGKSIRTVLT 374 +YG G E + + K +LD +ITH F+K E F+L+ +GK+ + V Sbjct: 287 -IYGITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFM 345 Query: 375 F 375 Sbjct: 346 L 346 >2EER-A nrPDB Length = 347 Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 47/377 (12%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG---------NLVTP 61 +A L E+ KP +ED+ + PK +V IK+ A G+C +D H+ G +L Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C +PR Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC-----DSPR 116 Query: 122 --GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFS 178 G DG +++Y +V + K+ S +E L G + Sbjct: 117 WLGINYDG------------------AYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVT 158 Query: 179 TGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 T AV A + P T V G GG+G A+ KA A II VD+ ++ AK G Sbjct: 159 T--YRAVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAG 216 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 A IN + P+ E+ + G D ++ T+ + G V+VG+ Sbjct: 217 ADYVINASS-QDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQ-GKYVMVGLFG 274 Query: 298 ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKIN 357 A P++ L + G++ G GI L A+ + ++T + E+ N Sbjct: 275 ADLKYH-APLITLNEVQFIGSLVGNQSDFLGIMSL-----AEAGKVKPMVTKTMKLEEAN 328 Query: 358 EGFDLLHSGKSI-RTVL 373 E D L + K++ R VL Sbjct: 329 EAIDNLENFKAVGRQVL 345 >5VM2-A nrPDB Length = 347 Score = 101 bits (251), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 93/354 (26%), Positives = 146/354 (41%), Gaps = 38/354 (10%) Query: 15 LWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDH-VVSGNLVTP----LPVILGHE 69 + +V I E+ PK EV IK+ VGIC +D H SG + P + LGHE Sbjct: 7 ILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHE 66 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTR 129 AG V +VG V KPGD+V CG CR C + N C D + + Sbjct: 67 CAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALT 126 Query: 130 RFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 + C + + L + + + E A + AA +A Sbjct: 127 HYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAM---------------------LAD 165 Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN--PQDY 247 V PG + G G +GL + CK GA I VD+ + + A A++LGAT IN +D Sbjct: 166 VKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDT 225 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 Q+ ++M G D FE G T+ + G +IVG P + +IN + Sbjct: 226 IARCQQFTEDM---GADIVFETAGSAVTVKQAPYLVMRG-GKIMIVGTVPGAS--AINFL 279 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 + T + F+ P + + +F + +++TH+ + + + F+ Sbjct: 280 KINREVTIQTV----FRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >6FG0-A nrPDB Length = 352 Score = 100 bits (250), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 79/273 (28%), Positives = 121/273 (44%), Gaps = 28/273 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV---SGNLVTPLPVILG 67 KA E+ + D+ P E+ +K+ A G+C +D V+ + LP+ LG Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKN-DLG-NPRGTLQ 125 HE G V +GEGVT GD V CG C C NYC + DLG P G Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPG--- 118 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTGYGSA 184 G P + ++Y +VD + I P+ L G + + + Sbjct: 119 --------YGSP-------GSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAIS 163 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 + + PGST V G+GG+G + +A AAR+IAVD++ D+ A A+E+GA + Sbjct: 164 RVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKS 223 Query: 245 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM 276 + ++E+T G G F+ +G T+ Sbjct: 224 ---GAGAADAIRELTGGQGATAVFDFVGAQSTI 253 >6N7L-A nrPDB Length = 353 Score = 98.6 bits (244), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 106/369 (28%), Positives = 156/369 (42%), Gaps = 56/369 (15%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVT--PLPVILGH 68 KAAV+ +P I++V V P YEV +K++A G+C TD H V G+ +P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E GIV + G VK GD V +P CG C C C G G DG Sbjct: 75 EGVGIVVACGPD-AMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNG---GYSVDG 130 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 F++Y + D V + + ++ I C T Y + Sbjct: 131 ------------------GFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGLKE 171 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 + PG A+ G+GG+G AV KA G + A+D+ DK AK+LGA +N + Sbjct: 172 TETKPGEWVAISGIGGLGHVAVQYAKAMG-MHVAAIDVADDKLELAKKLGADLTVNAK-- 228 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL--------LCCHEACGTSVIVGVPPAS 299 TD G EV G ++ ++ + GT + G+PP S Sbjct: 229 ----------TTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGS 278 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKS-KEGIPKLVADFMAKKFSLDALITHVLPFEKINE 358 L I +L T +G++ G K +E + DF A + + A +T E IN+ Sbjct: 279 FELPIFETVLKR-ITVRGSIVGTRKDLQEAL-----DF-ANEGLVKATVTSA-KLEDIND 330 Query: 359 GFDLLHSGK 367 FD + G+ Sbjct: 331 VFDKMKKGQ 339 >2DQ4-A nrPDB Length = 343 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 94/361 (26%), Positives = 154/361 (42%), Gaps = 43/361 (11%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-----VTPLPVILGHEAAGIVES 76 ++ D V P E+ +++ A IC TD H+ + + P P++ GHE +G+VE+ Sbjct: 13 LTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRP-PLVTGHEFSGVVEA 71 Query: 77 VGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGK 136 VG GV + GD V C C C+ + CL + G +DG Sbjct: 72 VGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQI---LGVDRDG--------- 119 Query: 137 PIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLI---GCGFSTGY-GSAVNVAKVTP 192 F++Y VV P E ++ G T Y GS V+ Sbjct: 120 ---------GFAEYVVVPAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVS------ 164 Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + + G G +GL A M +A+GA I+ D N + A A+ A +NP ++ + Sbjct: 165 GKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP--LEEDLL 221 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTG 312 EV++ +T GV+ E G + L+ G + I+G+P + L++ G Sbjct: 222 EVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIPSDPIRFDLAGELVMRG 280 Query: 313 RTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTV 372 T G G + + + A + + L L+TH LP + E F LL SG++++ + Sbjct: 281 ITAFG--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASGQAVKVI 338 Query: 373 L 373 L Sbjct: 339 L 339 >3GFB-A nrPDB Length = 350 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 102/374 (27%), Positives = 160/374 (42%), Gaps = 43/374 (11%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAY--EVRIKMVAVGICRTDDHVVSGN-----LVTPLP 63 K + + K + E VEV PK EV IK++A IC TD H+ N + P P Sbjct: 4 KMQAIMKTKPAYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP-P 62 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGT 123 I+GHE AG V VG GV ++ GD + CGKC CK+ + C + G Sbjct: 63 QIMGHEVAGEVVEVGPGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKI---FGV 119 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 DG F+ Y +V K P E L G+ Sbjct: 120 DMDGV------------------FAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGN 156 Query: 184 AVNVAKVTP--GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 AV+ P G + + G G +GL + KA+GA +I + ++ + AK++GA Sbjct: 157 AVDTVLAGPIAGRSTLITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYV 216 Query: 242 INPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 +NP + + P++ V+ ++TDG GV+ E G + L G ++G+ P Sbjct: 217 VNPFE-EDPVKFVM-DITDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFPREV 273 Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEG 359 + N +++ G G E + + + K +LD +ITH F+K E Sbjct: 274 TIDFNNLIIFKALEVHGIT--GRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEA 331 Query: 360 FDLLHSGKSIRTVL 373 F+L+ +GK+ + V Sbjct: 332 FELMRAGKTGKVVF 345 >1PL8-A nrPDB Length = 356 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 98/367 (26%), Positives = 159/367 (43%), Gaps = 53/367 (14%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIVESV 77 +E+ + P EV ++M +VGIC +D H GN + P++LGHEA+G VE V Sbjct: 19 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 78 Query: 78 GEGVTTVKPGDKV-IPLFTPQ-----CGKCRVCKNPESNYC-LKNDLGNPRGTLQDGTRR 130 G V +KPGD+V I P+ C R +P +C D GN Sbjct: 79 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN----------- 127 Query: 131 FTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKV 190 CR F + Y + D + PL S G A V Sbjct: 128 -LCR------FYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGV 169 Query: 191 TPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 T G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ Sbjct: 170 TLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKES 227 Query: 251 IQEVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 QE+ +++ +G + + + E G ++ A + GT V+VG+ ++ P Sbjct: 228 PQEIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVLVGL---GSEMTTVP 282 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +L R + G F+ P ++ +K ++ L+TH P EK E F+ G Sbjct: 283 LLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 340 Query: 367 KSIRTVL 373 ++ +L Sbjct: 341 LGLKIML 347 >4GKV-A nrPDB Length = 336 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 92/289 (31%), Positives = 134/289 (46%), Gaps = 32/289 (11%) Query: 36 EVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPLF 94 E +KM G+C TD HV +G+ VILGHE G+V VG GVT++KPGD+ + F Sbjct: 26 EALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWF 85 Query: 95 TPQCGKCRVCKNPESNYC--LKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTV 152 CG C C + C +KN G DG C + Y V Sbjct: 86 YEGCGHCEYCNSGNETLCRSVKN-----AGYSVDGGMAEEC-----------IVVADYAV 129 Query: 153 VDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGC 212 + + A+S I C T Y AV ++K+ PG A++GLGG+G A+ Sbjct: 130 KVPDGLDSAAASS-------ITCAGVTTY-KAVKLSKIRPGQWIAIYGLGGLGNLALQYA 181 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 K A++IA+D+N ++ A E+GA IN + + ++++E T G + V Sbjct: 182 KNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTEDAAKIVQEKTGGAH--AAVVTAV 237 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYG 321 S + A G V VG+PP S +L I P L+L G G++ G Sbjct: 238 AKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLVLDGIEVVGSLVG 285 >3QE3-A nrPDB Length = 355 Score = 92.0 bits (227), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 96/361 (26%), Positives = 161/361 (44%), Gaps = 41/361 (11%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIVESV 77 +E+ + P EV +KM +VGIC +D H G+ V P++LGHEA+G V V Sbjct: 18 LRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKV 77 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137 G V ++PGD+V Q G R +++ K N T+ F C P Sbjct: 78 GSLVRHLQPGDRV----AIQPGAPR-----QTDEFCKIGRYNLSPTI------FFCATPP 122 Query: 138 IHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 ++ + N K+ E+ LI S G A A VT G+ Sbjct: 123 -----DDGNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGI-HACRRAGVTLGNKVL 175 Query: 198 VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-----NPQDYKKPIQ 252 V G G +GL ++ KA GAA+++ D++ + +KAKE+GA + +P++ K ++ Sbjct: 176 VCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVE 235 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTG 312 +L + + E G ++ A + H GT V+VG+ S+ S+ L+ Sbjct: 236 GLLGSKP----EVTIECTGVETSIQAGIYATHSG-GTLVLVGL--GSEMTSVP---LVHA 285 Query: 313 RTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTV 372 T + + G F+ P ++ +K ++ L+TH P EK E F+ G ++ + Sbjct: 286 ATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVM 345 Query: 373 L 373 + Sbjct: 346 I 346 >4EJ6-A nrPDB Length = 370 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 97/346 (28%), Positives = 151/346 (43%), Gaps = 32/346 (9%) Query: 13 AVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAG 72 AV E S+ +V + P ++ +K+ A GIC TD H++ G + PV LGHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 IV G V + PG ++ CG+C C+ N C +N Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLC-RN----------------- 127 Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 R IH G F++Y +V +I L+ V C V+++ + Sbjct: 128 LRAIGIHRDGG---FAEYVLVPRKQAFEIPLT--LDPVHGAFCEPLACCLHGVDLSGIKA 182 Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKP 250 GST A+ G G +GL V + AGA +I K A+E+GAT ++P D + Sbjct: 183 GSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEA 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 I + + GGVD E G +T+ S +A GT VI+GV P + + I P +L Sbjct: 243 IAGPVG-LVPGGVDVVIECAGVAETVKQSTRLA-KAGGTVVILGVLPQGEKVEIEPFDIL 300 Query: 311 TGRTWKGAVYGGFKSKEGIPKLVADFMAK-KFSLDALITHVLPFEK 355 R + V G F + + + AD +A +D +I+ + ++ Sbjct: 301 F-RELR--VLGSFINPF-VHRRAADLVATGAIEIDRMISRRISLDE 342 >2H6E-A nrPDB Length = 344 Score = 91.3 bits (225), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 103/373 (27%), Positives = 165/373 (44%), Gaps = 50/373 (13%) Query: 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP---LP 63 ++K KAA+L + +P SIEDV + P+ EV I++ G+CRTD V G LP Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGT 123 +ILGHE AG + VGE + VK GD V+ T CR C+ + N C KN + P T Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC-KNQI-IPGQT 117 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENA-VAKIDAASPLEKVCLIGCGFSTGYG 182 G FS+Y +V + + K+++ SP+E L G +T G Sbjct: 118 TNGG-------------------FSEYMLVKSSRWLVKLNSLSPVEAAPLADAG-TTSMG 157 Query: 183 S---AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAK--AKELG 237 + A+ V G+GG+ + + KA I V I++ K + A ELG Sbjct: 158 AIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKAL-MKNITIVGISRSKKHRDFALELG 216 Query: 238 ATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM--MASLLCCHEACGTSVIVG 294 A +D + ++ ++TDG G + +++G +T + LL G ++VG Sbjct: 217 ADYVSEMKDA----ESLINKLTDGLGASIAIDLVGTEETTYNLGKLLAQE---GAIILVG 269 Query: 295 VPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFE 354 + +L + + G+ YG E + +L K + + +P + Sbjct: 270 MEGKRVSLEAFDTAVWNKKLL-GSNYGSLNDLEDVVRLSESGKIKPYIIK------VPLD 322 Query: 355 KINEGFDLLHSGK 367 IN+ F L G+ Sbjct: 323 DINKAFTNLDEGR 335 >5ENV-A nrPDB Length = 347 Score = 90.9 bits (224), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 88/294 (29%), Positives = 123/294 (41%), Gaps = 29/294 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVILGH 68 K + +E +D+ V PKA E+ I + G+C TD H G+ P LP++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E AG+V +GE V K GD I C C C+ + C DL G DG Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADL---SGYTHDG 123 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 +F QY D A I + L +V I C T Y A+ Sbjct: 124 ------------------SFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKS 164 Query: 188 AKVTPGSTCAVFG-LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG+G AV KA G R++ +D + K + +G I+ Sbjct: 165 ANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTK 223 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 K + VLK TDGG V + AS A GT+V+VG+P ++ Sbjct: 224 EKDIVGAVLK-ATDGGAHGVINVSVSEAAIEASTRYV-RANGTTVLVGMPAGAK 275 >1R37-A nrPDB Length = 347 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 106/378 (28%), Positives = 164/378 (43%), Gaps = 49/378 (12%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG---------NLVTP 61 +A L E+ KP S++++ V PK +V IK+ A G+C +D H+ G +L Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C +PR Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC-----DSPR 116 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTS---TFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGF 177 +LG + +++Y +V + K+ + +E L G Sbjct: 117 -------------------WLGINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGI 157 Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVGLS-AVMGCKAAGAARIIAVDINKDKFAKAKEL 236 +T AV A + P T V G GG + AV KA A II VD+ ++ AK Sbjct: 158 TT--YRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRA 215 Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 GA IN + P+ E+ + GVD ++ T+ + G V+VG+ Sbjct: 216 GADYVINA-SMQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQ-GKYVMVGLF 273 Query: 297 PASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKI 356 A + P++ L+ + G++ G GI +L A+ + +IT + E+ Sbjct: 274 GADLHYH-APLITLSEIQFVGSLVGNQSDFLGIMRL-----AEAGKVKPMITKTMKLEEA 327 Query: 357 NEGFDLLHSGKSI-RTVL 373 NE D L + K+I R VL Sbjct: 328 NEAIDNLENFKAIGRQVL 345 >1YKF-A nrPDB Length = 352 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 97/341 (28%), Positives = 153/341 (44%), Gaps = 34/341 (9%) Query: 32 PKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV 90 P ++ ++ +AV C +D H V G + +ILGHEA G V VG V KPGD+V Sbjct: 22 PGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDFKPGDRV 81 Query: 91 I-PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQ 149 + P TP V + + G + G + + F + Sbjct: 82 VVPAITPDWRTSEVQRGYHQH----------SGGMLAGWKFSNVK---------DGVFGE 122 Query: 150 YTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLS 207 + V++ +A + PLE +I +TG+ A +A + G+T AV G+G VGL Sbjct: 123 FFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVLGIGPVGLM 181 Query: 208 AVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFS 266 AV G K GA RIIAV AK GAT+ +N +D PI+ + +T+G GVD + Sbjct: 182 AVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEGKGVDAA 239 Query: 267 FEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL---LTGRTWKGAVYGGF 323 G D +MA+ + + GT V + L + + + +T KG + G Sbjct: 240 IIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGLCPGG 298 Query: 324 KSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLL 363 + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 299 RLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >3TWO-A nrPDB Length = 348 Score = 88.2 bits (217), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 85/325 (26%), Positives = 136/325 (41%), Gaps = 32/325 (9%) Query: 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL-PVIL 66 ++ K ++ + F D +V I ++ GIC +D H + P+I Sbjct: 3 VQSKGFAIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIP 62 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE AGI++ VG+GV K GD V + F C C+ CK + +C K Sbjct: 63 GHEIAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKV---------- 112 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + C + +S VVDEN V +D +PLEKV + C T Y S + Sbjct: 113 --VFTYDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTY-SPL 169 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NP 244 +KVT G+ V G GG+G AV A G A + N+ K A +G +P Sbjct: 170 KFSKVTKGTKVGVAGFGGLGSMAVKYAVAMG-AEVSVFARNEHKKQDALSMGVKHFYTDP 228 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--ASQNL 302 + K+ + ++ + +++ L + + G +VG+PP + L Sbjct: 229 KQCKEELDFIISTIPT-----HYDLKDYLKLLTYN--------GDLALVGLPPVEVAPVL 275 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKE 327 S+ + L R G++ GG K + Sbjct: 276 SVFDFIHLGNRKVYGSLIGGIKETQ 300 >3FPL-A nrPDB Length = 351 Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 108/343 (31%), Positives = 153/343 (44%), Gaps = 42/343 (12%) Query: 34 AYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI- 91 +Y+ ++ +AV C +D H V G L +ILGHEA G V VG V KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIV 83 Query: 92 PLFTPQCGKCRVCK--NPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQ 149 P TP V SN L G +DG F + Sbjct: 84 PCTTPDWRSLEVQAGFQQHSNGMLA---GWKFSNFKDGV------------------FGE 122 Query: 150 YTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLS 207 Y V++ +A + PLE +I +TG+ A +A + G+T AV G+G VGL Sbjct: 123 YFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAVLGIGPVGLM 181 Query: 208 AVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFS 266 AV G K GA RIIAV AK GAT+ +N +D PI+ + +T+G GVD + Sbjct: 182 AVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEGKGVDAA 239 Query: 267 FEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL----LTGRTWKGAV-YG 321 G D +MA+ + + GT V + L + P L + +T KG + G Sbjct: 240 IIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPV-PRLEWGCGMAHKTIKGGLCPG 297 Query: 322 GFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLL 363 G E + +V + + L L+THV F+ I E L+ Sbjct: 298 GRLRAEMLRDMV---VYNRVDLSKLVTHVYHGFDHIEEALLLM 337 >5K1S-A nrPDB Length = 362 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 85/295 (28%), Positives = 130/295 (44%), Gaps = 35/295 (11%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGEG 80 +E + + P EV +++ A G+C D GNL T +P ILGHEAAG V VG Sbjct: 32 LKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILGHEAAGEVIEVGPD 91 Query: 81 VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHH 140 K GD+ L CG C +C++ ++ C ++ RF P Sbjct: 92 TPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDN-------------RFFGEELP--- 135 Query: 141 FLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG 200 ++Q+ V + ++ A+ P + + C T + KV G T + G Sbjct: 136 ----GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRGKVRAGETVLITG 191 Query: 201 L-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKPIQEVLKE 257 GGVGLS+V + G AR+IAV ++ K KE GA E I + D+ +V K Sbjct: 192 ASGGVGLSSVQLARLDG-ARVIAVTSSEAKVQALKEAGADEVIVSRGLDFAS---DVRKR 247 Query: 258 MTDGGVDFSFEVIGR--LDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 GVD + E++G D + S+ A G V+V S + +NP L++ Sbjct: 248 TQGAGVDVAVEIVGSATFDQTLKSM-----APGGRVVVVGNLESGMVQLNPGLVI 297 >4UEJ-A nrPDB Length = 346 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/226 (29%), Positives = 103/226 (45%), Gaps = 28/226 (12%) Query: 36 EVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV--IPL 93 EVR+K+ + G+C +D + N P+ LGHE +G +++VG GV + PGD V +PL Sbjct: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 Query: 94 FTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV 153 C C C + C K D G+ +DG F++Y VV Sbjct: 87 LP--CFTCPECLKGFYSQCAKYDF---IGSRRDG------------------GFAEYIVV 123 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCK 213 V + P+E I + G A ++A+ + G G +GL A+ Sbjct: 124 KRKNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAV 181 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 258 A GA + A+DI+ +K A AK GA + N + P +Q VL+E+ Sbjct: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 >5KIA-A nrPDB Length = 351 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 88/346 (25%), Positives = 151/346 (43%), Gaps = 38/346 (10%) Query: 36 EVRIKMVAVGICRTDDHVVSGN----LVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI 91 +V IK+ IC TD H+ + P+P+ +GHE G + +G+ V GD+V Sbjct: 35 DVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRVS 94 Query: 92 PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYT 151 CG CR C+ + C R T+ G R + +L F+ + Sbjct: 95 GEGHITCGFCRNCRAGRRHLC--------RNTVGVGVNREGAFAE----YLAIPAFNAFK 142 Query: 152 VVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMG 211 + E + + + I F +A++ V G + G G +G+ AV Sbjct: 143 IPPEIS----------DDLAAIFDPFGNATHTALSFNLV--GEDVLITGAGPIGVMAVAI 190 Query: 212 CKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE--MTDGGVDFSFEV 269 K GA ++ DIN + A+ +GAT +N ++ +++V+ + MT+ G D E+ Sbjct: 191 AKHVGARNVVITDINDYRLDLARRMGATRAVNVS--RESLRDVMADLHMTE-GFDVGLEM 247 Query: 270 IGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGI 329 G + + SLL G ++G+PPA + N ++ G KG +YG + E Sbjct: 248 SG-VPSAFTSLLESMNHGGKVALLGIPPAQTAIDWN-QVIFKGLEIKG-IYGR-EMFETW 303 Query: 330 PKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF 375 K+VA + L +ITH + +GF + SG+S + +L + Sbjct: 304 YKMVA-MLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDW 348 >4ILK-A nrPDB Length = 359 Score = 84.3 bits (207), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 99/377 (26%), Positives = 150/377 (39%), Gaps = 56/377 (14%) Query: 13 AVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG-NLVTPLPVILGHEAA 71 ++L E SI + E+ P A EVR+K+ GIC +D H+ G N P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G++++VGEGV + + G++V CG C C + N C + G DG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADGG--- 136 Query: 132 TCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIG----CGFSTGYGSAVNV 187 FS+Y VV KI A + +I TG+G Sbjct: 137 ---------------FSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQP--- 178 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAA-GAARIIAVDINKDKFAKAKELGATECINPQD 246 T T V+G G +GL+ V K +I D ++ KAKE GA IN + Sbjct: 179 ---TENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--N 233 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS---QNLS 303 + P+ E SF G T++ C +V + P A S Sbjct: 234 SQTPLGE------------SFAEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFS 281 Query: 304 INPMLLLTGRTWKGAVYGGFKSKEGIPK--LVADFMAKKF-SLDALITHVLPFEKINEGF 360 P ++ + G F S+ K +V D+++K + LITH F+ + + Sbjct: 282 SEPSEVIQ-QGITGKELSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAI 340 Query: 361 DL--LHSGKSIRTVLTF 375 L L + +LTF Sbjct: 341 SLFELDQKHCCKVLLTF 357 >4OH1-A nrPDB Length = 351 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 93/362 (25%), Positives = 150/362 (41%), Gaps = 50/362 (13%) Query: 26 DVEVAP---PKAYEVRIKMVAVGICRTDDHVVSGNL-------VTPLPVILGHEAAGIVE 75 D+ AP PK E+RIK+V IC +D H+++GNL + LP+ GHE +G+++ Sbjct: 22 DMMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVID 81 Query: 76 SVGEGVTTV--KPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTC 133 VG + K G KV+ + CG C C+ + N C + G +G Sbjct: 82 KVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLC------SNMGYRMNG------ 129 Query: 134 RGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 FS+Y V + + I + L+ L+ T S+ AK++ G Sbjct: 130 -------------FSEYAVYHMSQIFPIPDDADLKDYALVEP--LTVALSSAEQAKISYG 174 Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + A+ G GG+G+ V + AGA+ I DI +K A E GA +N + + + E Sbjct: 175 KSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EGVAE 232 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASL-LCCHEACGTSVIVGVPPASQNLSINPMLLLTG 312 E+ G D E G T A L L G +V + L +N L + Sbjct: 233 RAIELAGGRYDCVLEGTGA--TAAAKLGLQLLARDGDAVYFAMYGKDPILPVN---LQSD 287 Query: 313 RTW-KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRT 371 W + ++G + PK + M + +I + F+ L+S K + Sbjct: 288 LYWDQKHIHGMIQGAWQFPKSIR--MIPRMDFSKIIQKEHTLTNYKQAFEDLYSKKYAKI 345 Query: 372 VL 373 V+ Sbjct: 346 VI 347 >5YAT-A nrPDB Length = 350 Score = 81.6 bits (200), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 78/256 (30%), Positives = 110/256 (42%), Gaps = 27/256 (10%) Query: 11 KAAVLWEVKK-PFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN--LVTPLPVILG 67 + AV++E P +D+ V PK+ E+ I + G+C TD H G+ L LP++ G Sbjct: 9 QKAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGG 68 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 HE AG+V + GE VT + GD I C C C + C K DL G D Sbjct: 69 HEGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADL---SGFTHD 125 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G +F QY D A+I + L +V I C T Y A+ Sbjct: 126 G------------------SFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALK 166 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG S + A R++ +D DK K LGA ++ Sbjct: 167 TADLRIGQWVAISGAGGGLGSLAVQYAKALGLRVLGIDGGADKGEFVKSLGAEVFVDFTK 226 Query: 247 YKKPIQEVLKEMTDGG 262 K + EV K +T+GG Sbjct: 227 TKDVVAEVQK-LTNGG 241 >4JLW-A nrPDB Length = 399 Score = 80.9 bits (198), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 69/206 (33%), Positives = 98/206 (47%), Gaps = 12/206 (5%) Query: 35 YEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 + V +++V+ IC +D H+V G P ++LGHE G V +G GV T+K GD V F Sbjct: 35 HGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEITGEVVEIGRGVETMKIGDLVSVPF 94 Query: 95 TPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVD 154 CG CR CK + CL NP G + G + G + + D Sbjct: 95 NVACGHCRTCKEQHTGVCLTV---NP--ARAGGAYGYVDMGGWVG---GQAEYVLVPYAD 146 Query: 155 ENAVAKIDAASPLEKVCLIGCG---FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMG 211 N + + + +EK+ + C TGY AV A V PGST + G G VGL+A Sbjct: 147 FNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAVT-AGVGPGSTVYIAGAGPVGLAAAAS 205 Query: 212 CKAAGAARIIAVDINKDKFAKAKELG 237 + GAA +I D+N + A AK+ G Sbjct: 206 ARLLGAAVVIVGDVNPTRLAHAKKQG 231 >1KEV-A nrPDB Length = 351 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 75/237 (31%), Positives = 104/237 (43%), Gaps = 29/237 (12%) Query: 34 AYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI- 91 +Y+ ++ +AV C +D H V G L +ILGHEA G V VG V KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIV 83 Query: 92 PLFTPQCGKCRVCK--NPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQ 149 P TP V SN L G +DG F + Sbjct: 84 PCTTPDWRSLEVQAGFQQHSNGMLA---GWKFSNFKDGV------------------FGE 122 Query: 150 YTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLS 207 Y V++ +A + PLE +I +TG+ A +A + GS+ V G+G VGL Sbjct: 123 YFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVVIGIGAVGLM 181 Query: 208 AVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 + G K GA RII V AK GAT+ +N ++ + +V+K GVD Sbjct: 182 GIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGKGVD 237 >3FPC-A nrPDB Length = 352 Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 106/243 (43%), Gaps = 29/243 (11%) Query: 28 EVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKP 86 E P ++ ++ +AV C +D H V G + +ILGHEA G V VG V KP Sbjct: 18 EKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDFKP 77 Query: 87 GDKVI-PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTS 145 GD+V+ P TP V + + G + G + + Sbjct: 78 GDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGWKFSNVK---------DG 118 Query: 146 TFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 F ++ V++ +A + PLE +I +TG+ A +A + G T V G+G Sbjct: 119 VFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVIGIGP 177 Query: 204 VGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDG 261 VGL +V G GA RI AV K A E GAT+ IN YK ++++LK Sbjct: 178 VGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIIN---YKNGDIVEQILKATDGK 234 Query: 262 GVD 264 GVD Sbjct: 235 GVD 237 >3FSR-A nrPDB Length = 352 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 89/349 (25%), Positives = 147/349 (42%), Gaps = 42/349 (12%) Query: 28 EVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKP 86 E P ++ ++ +AV C +D H V G + +ILGHEA G V VG V KP Sbjct: 18 EKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDFKP 77 Query: 87 GDKVI-PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTS 145 GD+V+ P TP V + + G + G + + Sbjct: 78 GDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGWKFSNVK---------DG 118 Query: 146 TFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 F ++ V++ +A + PLE +I +TG+ A +A + GS+ V G+G Sbjct: 119 VFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVIGIGA 177 Query: 204 VGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGV 263 VGL + G K GA RII V AK GAT+ +N ++ + +V+K GV Sbjct: 178 VGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGKGV 236 Query: 264 DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL--------LTGRTW 315 D G +T+ ++ S I + + S + +L+ + +T Sbjct: 237 DRVIMAGGGSETLSQAVSMVKPGGIISNI------NYHGSGDALLIPRVEWGCGMAHKTI 290 Query: 316 KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLL 363 KG + G + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 291 KGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >3WLE-A nrPDB Length = 341 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 90/313 (28%), Positives = 141/313 (45%), Gaps = 35/313 (11%) Query: 25 EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 D+ V PKA ++ +K+ AVG+C +D HV+ L ++GHE AG V +VG+ V Sbjct: 27 NDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINY 86 Query: 85 KPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGT 144 K GD+V + CG C+ C+ N C KN G+ G DG +L Sbjct: 87 KVGDRVACVGPNGCGGCKYCRGAIDNVC-KNAFGDWFGLGYDGG---------YQQYLLV 136 Query: 145 STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGV 204 + + + +N A + AAS + T Y A+ +A+V+P S + G GG+ Sbjct: 137 TRPRNLSRIPDNVSADVAAASTDAVL--------TPY-HAIKMAQVSPTSNILLIGAGGL 187 Query: 205 GLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G +A+ KA G A++ +D K+ +AK+LGA + E L E G Sbjct: 188 GGNAIQVAKAFG-AKVTVLDKKKEARDQAKKLGADA----------VYETLPESISPG-- 234 Query: 265 FSFEVIGRLDTMMASLLCCHEACG-TSVIVGVPPASQNLSIN-PMLLLTGRTWKGAVYGG 322 SF ++ A+ C + VI+ V + NLS N L L G+ +G Sbjct: 235 -SFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGDLALREIRILGSFWGT 293 Query: 323 FKSKEGIPKLVAD 335 + + KLV++ Sbjct: 294 TNDLDDVLKLVSE 306 >1KOL-A nrPDB Length = 398 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 96/209 (45%), Gaps = 18/209 (8%) Query: 35 YEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 + V +K+V+ IC +D H+V G + ++LGHE G V G V ++ GD V F Sbjct: 34 HGVILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPF 93 Query: 95 TPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV- 153 CG+CR CK + CL NP G + G T ++Y +V Sbjct: 94 NVACGRCRSCKEMHTGVCLTV---NP--ARAGGAYGYVDMGD------WTGGQAEYVLVP 142 Query: 154 --DENAVAKIDAASPLEKVCLIGCG---FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSA 208 D N + D +EK+ + C TGY AV A V PGST V G G VGL+A Sbjct: 143 YADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAVT-AGVGPGSTVYVAGAGPVGLAA 201 Query: 209 VMGCKAAGAARIIAVDINKDKFAKAKELG 237 + GAA +I D+N + A AK G Sbjct: 202 AASARLLGAAVVIVGDLNPARLAHAKAQG 230 >2DPH-A nrPDB Length = 398 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 77/247 (31%), Positives = 108/247 (43%), Gaps = 15/247 (6%) Query: 35 YEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 + V +K+V+ IC +D H+ G + P +LGHE G V G V + GD V F Sbjct: 33 HAVILKVVSTNICGSDQHIYRGRFIVPKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPF 92 Query: 95 TPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVD 154 CG+CR CK S+ C +N+L NP L G F +G G + + D Sbjct: 93 NVACGRCRNCKEARSDVC-ENNLVNPDADL--GAFGFDLKGWS----GGQAEYVLVPYAD 145 Query: 155 ENAVAKIDAASPLEKV---CLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMG 211 + D +EK+ LI TG+ V+ A V PGS + G G VG A G Sbjct: 146 YMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVS-AGVKPGSHVYIAGAGPVGRCAAAG 204 Query: 212 CKAAGAARIIAVDINKDKFAKAKELG--ATECINPQDYKKPIQEVL-KEMTDGGVD-FSF 267 + GAA +I D N ++ + G + N + I ++L K D GVD F Sbjct: 205 ARLLGAACVIVGDQNPERLKLLSDAGFETIDLRNSAPLRDQIDQILGKPEVDCGVDAVGF 264 Query: 268 EVIGRLD 274 E G D Sbjct: 265 EAHGLGD 271 >5VKT-A nrPDB Length = 362 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 53/162 (32%), Positives = 69/162 (42%), Gaps = 18/162 (11%) Query: 36 EVRIKMVAVGICRTDDHVVSGNLVTPL-PVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V IK++ GIC TD HV+ + PV+ GHE G+V VG GVT K GD V + Sbjct: 36 DVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGDTVGVGY 95 Query: 94 FTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTST--FSQYT 151 F C C C NYC DL T G HH T+ FS Sbjct: 96 FVDSCRTCESCSTGHENYC--PDL------------VLTSNGVDHHHHGATTKGGFSDVL 141 Query: 152 VVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 VV ++ V ++ + PL+ + C T Y A PG Sbjct: 142 VVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPG 183 >1UUF-A nrPDB Length = 369 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 95/372 (25%), Positives = 150/372 (40%), Gaps = 51/372 (13%) Query: 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TPLPVIL 66 +K KA + K+P D+ P +V+I++ G+C +D H V T P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG+ V PGD V + C C C++ NYC Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYC----------DHM 130 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIG---CGFSTGYG 182 GT +P H G +SQ VV E V +I P E++ + C T Y Sbjct: 131 TGTYNSPTPDEPGHTLGG---YSQQIVVHERYVLRI--RHPQEQLAAVAPLLCAGITTY- 184 Query: 183 SAVNVAKVTPGSTCAVFGLG-----GVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 S + + PG V G+G G+ L+ MG A ++A ++ K AK LG Sbjct: 185 SPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMG------AHVVAFTTSEAKREAAKALG 238 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIG---RLDTMMASLLCCHEACGTSVIVG 294 A E +N ++ + + LK DF + LD L + GT +VG Sbjct: 239 ADEVVNSRNADE-MAAHLKSF-----DFILNTVAAPHNLDDFTTLL----KRDGTMTLVG 288 Query: 295 VPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFE 354 P L++ R G++ GG + + DF A+ + + ++ + Sbjct: 289 APATPHKSPEVFNLIMKRRAIAGSMIGGIPETQEM----LDFCAEHGIVADI--EMIRAD 342 Query: 355 KINEGFDLLHSG 366 +INE ++ + G Sbjct: 343 QINEAYERMLRG 354 >3IP1-A nrPDB Length = 404 Score = 67.8 bits (164), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 90/366 (24%), Positives = 150/366 (40%), Gaps = 59/366 (16%) Query: 33 KAYEVRIKMVAVGICRTDDHVVS----GNLVTP----LPVILGHEAAGIVESVGEGVTTV 84 K E+ IK+ A GIC +D H+ G ++ P PV LGHE +G+V G Sbjct: 54 KPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSGVVVEAGPEAINR 113 Query: 85 KP------GDKVIPLFTPQCGKCRVCKNPESNYCLK-NDLGNPRGTLQDGTRRFTCRGKP 137 + G+ V CG CR C N+C N+LG F G Sbjct: 114 RTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELG------------FNVDG-- 159 Query: 138 IHHFLGTSTFSQYTVVDEN---AVAKIDAASPLEKVCLIGCGF---STGYGSA-VNVAKV 190 F++Y VD ++ +++ +++ L G S Y + V + Sbjct: 160 --------AFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGI 211 Query: 191 TPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 PG + G G +GL+AV K AGA+++I + ++ + AKELGA I+P K+ Sbjct: 212 RPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPT--KEN 269 Query: 251 IQEVLKEMTDG-GVDFSFEVIGRLDTMMASL-LCCHEACGTSVIVGVPPASQNLSINPML 308 E + + T+G G E G + + A G + V + + + + Sbjct: 270 FVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVARA-----DAKI 324 Query: 309 LLTGRTW---KGAVYG--GFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 LTG + + + G G P++++ MA + +I+ + E+I E L Sbjct: 325 PLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTVSMEEIPEYIKRL 383 Query: 364 HSGKSI 369 + KS+ Sbjct: 384 QTDKSL 389 >2OUI-A nrPDB Length = 360 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 78/242 (32%), Positives = 105/242 (43%), Gaps = 49/242 (20%) Query: 39 IKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI-PLFTP 96 ++ +A+ C +D H V +G + +ILGHEA G + VG V +K GDKVI P TP Sbjct: 29 VRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITP 88 Query: 97 QCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHH--FLGTSTFSQYT--V 152 G+ ES RG P+H LG FS + V Sbjct: 89 DWGE------EESQ-----------------------RGYPMHSGGMLGGWKFSNFKDGV 119 Query: 153 VDE-NAVAKIDAASPL-------EKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGV 204 E V + DA L E ++ +TG+ A +A + G T V G+G V Sbjct: 120 FSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDTVCVIGIGPV 178 Query: 205 GLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGG 262 GL +V G GA RI AV K A E GAT+ IN YK ++++LK G Sbjct: 179 GLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIIN---YKNGDIVEQILKATDGKG 235 Query: 263 VD 264 VD Sbjct: 236 VD 237 >5Z0C-A nrPDB Length = 374 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 92/313 (29%), Positives = 124/313 (39%), Gaps = 40/313 (12%) Query: 36 EVRIKMVAVGICRTDDHVVSGNLV-TPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V K++ GIC +D H + T P + GHE G V VG V K GDKV + Sbjct: 40 DVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGC 99 Query: 94 FTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV 153 C C C N NYC P L G+R + L +S VV Sbjct: 100 IVGSCHSCPNCNNHLENYC-------PNRILTFGSRYYDGT-------LNHGGYSDLMVV 145 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCK 213 E+ +I A PL+ + C T Y PG V GLGG+G AV K Sbjct: 146 QEHFAVRIPDALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAK 205 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 A G + K LGA I D ++ +Q + M G + Sbjct: 206 AFGVKVTVVSTSPAKKEDAISGLGAHSFILSTDAEQ-MQAAVGTMD-----------GII 253 Query: 274 DTMMAS-----LLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTW-KGAVYGGFKSKE 327 DT+ AS L+ ++ G V+VG PP L + P+LL GR G+ GG K + Sbjct: 254 DTVSASHPLPPLISLLKSHGKLVMVGDPPKPLELPVFPLLL--GRKMVAGSAIGGMKETQ 311 Query: 328 GIPKLVADFMAKK 340 + DF AK+ Sbjct: 312 EM----IDFAAKE 320 >5H82-A nrPDB Length = 389 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 89/342 (26%), Positives = 141/342 (41%), Gaps = 33/342 (9%) Query: 35 YEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 ++V+ K++ G+C D T P + GHE GIV +G V K GDKV + Sbjct: 54 HDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVGVG 113 Query: 93 LFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLG-------TS 145 F CGKC C YC P+ DGT F+ ++ + Sbjct: 114 NFIGSCGKCERCNEGLEPYC-------PKVIYTDGT-AFSDENNTVYGDVSGDGEDRIYG 165 Query: 146 TFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVG 205 +S V +E V + PL I CG Y + PG + V G G +G Sbjct: 166 GYSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIG 225 Query: 206 LSAVMGCKAAGA-ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 AV KA GA +I+ I+K + A K I+ K+P + E T G+ Sbjct: 226 KLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLIS----KEPEEMKAAESTLDGI- 280 Query: 265 FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFK 324 F+ + + + LL + GT V++GV + L ++P LL+ R + G++ G K Sbjct: 281 --FDCVPSV-HPLHPLLNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMK 336 Query: 325 SKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 + + DF AK + + ++P + +N + + G Sbjct: 337 ETQEM----LDFAAKHNIVSDI--ELIPMDYVNTALERIAKG 372 >1E3J-A nrPDB Length = 352 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 27/210 (12%) Query: 12 AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILG 67 +AVL++ + +E + PK EV ++M VGIC +D H + + P+++G Sbjct: 7 SAVLYK-QNDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 HEA+G V VG+ V +K GD+V C +C+ CK + N C P T Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLC-------PDLTF--- 115 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 C P ++Y V + K+ LE+ L+ S G A Sbjct: 116 -----CATPP-----DDGNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGV-HACRR 163 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGA 217 A V G+T V G G +GL +V+ KA GA Sbjct: 164 AGVQLGTTVLVIGAGPIGLVSVLAAKAYGA 193 >3UOG-A nrPDB Length = 363 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 72/268 (26%), Positives = 113/268 (42%), Gaps = 48/268 (17%) Query: 17 EVKKPFSIEDVEVAPPKA--YEVRIKMVAVGICRTDDHVVSGNLVTPL--PVILGHEAAG 72 E P ++ E P+A +++ ++ +AV + D V+ + L P + + +G Sbjct: 34 ETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSG 93 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 +VE+VG+ VT +PGD+VI F P G L DG R T Sbjct: 94 VVEAVGKSVTRFRPGDRVISTFAP-------------------------GWL-DGLRPGT 127 Query: 133 CRGKPIHHFLGTS---TFSQYTVVDEN----AVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 R P + LG + S+Y V+ E A +DAA + + C T + + V Sbjct: 128 GR-TPAYETLGGAHPGVLSEYVVLPEGWFVAAPKSLDAA----EASTLPCAGLTAWFALV 182 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-- 243 + G V G GGV L + KA G A +I +++K +A LGA IN Sbjct: 183 EKGHLRAGDRVVVQGTGGVALFGLQIAKATG-AEVIVTSSSREKLDRAFALGADHGINRL 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIG 271 +D+ ++ V D G D E+ G Sbjct: 242 EEDW---VERVYALTGDRGADHILEIAG 266 >4OAQ-A nrPDB Length = 367 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 86/369 (23%), Positives = 153/369 (41%), Gaps = 38/369 (10%) Query: 16 WEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLP---VILGHEAAG 72 W K S E ++ P ++V +K G+C +D H +S PL +++GHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGW-QPLQRDNLVVGHEIIG 75 Query: 73 IVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 131 V +VG+ VT K GD+V I + C C+ C + YC + G + Sbjct: 76 EVIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYC------------KQGAATY 123 Query: 132 TCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV-NVAKV 190 + ++++ +S +++ DE V I P + C T + + N+ Sbjct: 124 NSKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLD 183 Query: 191 TPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 G + G+GG+G A+ A G A + A + K +A +LGA + + + K Sbjct: 184 ARGKNVGIIGIGGLGHLALQFANAMG-ANVTAFSRSSSKKEQAMKLGAHDFVATGEDKTW 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTM-MASLLCCHEACGTSVIVGVPPASQNLSINPMLL 309 + D DF +D + ++ L + V VG+PP+ ++P Sbjct: 243 YKNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTF 297 Query: 310 LTGRTWKGAVYGG--FKSKEGIPKLVADFMAKKFSLDALITHV-LPFEKINEGFDLLHSG 366 L +GA +G SK + +++ +A K ++ +I V + E + D H+G Sbjct: 298 LQ----QGASFGSSLLGSKTEVKEMLN--LAAKHNVRPMIEEVPISEENCAKALDRCHAG 351 Query: 367 KSIRTVLTF 375 +R F Sbjct: 352 -DVRYRFVF 359 >6DKH-A nrPDB Length = 346 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 79/326 (24%), Positives = 127/326 (38%), Gaps = 34/326 (10%) Query: 39 IKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF 94 +++ GIC +D H GN + P++LGHE G V + + + G V Sbjct: 35 VQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINP 92 Query: 95 TPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVD 154 + CG C+ C N C D+ RF H G F++Y +V+ Sbjct: 93 SKPCGHCKYCIEHNENQC--TDM------------RFFGSAMYFPHVDGG--FTRYKMVE 136 Query: 155 ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKA 214 + A + EKV + +A ++ G + G+G +G V K Sbjct: 137 TSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVKT 194 Query: 215 AGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLD 274 GAA I+ D++ + KE+GA +NPQ+ + K G D SFEV G Sbjct: 195 LGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEK----GYFDVSFEVSGHPS 250 Query: 275 TMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVA 334 ++ L A G V VG+ A PM+ L G+ + ++ G F+ V+ Sbjct: 251 SVNTCLEVT-RARGVMVQVGMGGAMAEF---PMMTLIGK--EISLRGSFRFTSEFNTAVS 304 Query: 335 DFMAKKFSLDALITHVLPFEKINEGF 360 + L++ PF + E Sbjct: 305 WLANGVINPLPLLSAEYPFTDLEEAL 330 >3M6I-A nrPDB Length = 363 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 83/359 (23%), Positives = 151/359 (42%), Gaps = 45/359 (12%) Query: 15 LWEVKKPFSIEDVEVAPP-KAYEVRIKMVAVGICRTDDHVVSGNLVTPLPV----ILGHE 69 LW + S+E V+ K EV + + + GIC +D H + P+ V +LGHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQ--CGKCRVCKNPESNYCLKND-LGNPRGTLQD 126 +AG V +V V ++K GD+V PQ C C C N C + D L P + Sbjct: 80 SAGEVIAVHPSVKSIKVGDRV--AIEPQVICNACEPCLTGRYNGCERVDFLSTP--PVPG 135 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 RR+ H +G ++ +++ +VA + + Sbjct: 136 LLRRYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQ 173 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A V G + G G +GL ++ KAAGA ++ DI++ + AKE+ E + + Sbjct: 174 RAGVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEI-CPEVVTHKV 232 Query: 247 YKKPIQEVLKEMTD--GGVD--FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 + +E K++ + GG++ + E G +++ +A+ + + G ++GV +N Sbjct: 233 ERLSAEESAKKIVESFGGIEPAVALECTG-VESSIAAAIWAVKFGGKVFVIGV---GKNE 288 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 P + + R + + ++ P+ + L L+TH P E + F+ Sbjct: 289 IQIPFMRASVR--EVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFE 345 >2VCY-A nrPDB Length = 344 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 62/250 (24%) Query: 20 KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN--LVTPLPVILGHEAAGIVESV 77 K ++++E+A + +VR+KM+A I +D +++ GN L+ LP + G+E V +V Sbjct: 27 KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAV 86 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137 G VT +KPGD VIP Sbjct: 87 GSNVTGLKPGDWVIPANA------------------------------------------ 104 Query: 138 IHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STC 196 G T+ V E A+ ++ + PL+ +G T Y ++ ++ PG S Sbjct: 105 -----GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 159 Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAV-----DINK--DKFAKAKELGATECINPQDYKK 249 GVG AV+ AA R I V DI K D+ K LGA I ++ ++ Sbjct: 160 QNASNSGVG-QAVIQIAAALGLRTINVVRDRPDIQKLSDRL---KSLGAEHVITEEELRR 215 Query: 250 P-IQEVLKEM 258 P ++ K+M Sbjct: 216 PEMKNFFKDM 225 >5FI5-A nrPDB Length = 357 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 79/311 (25%), Positives = 121/311 (38%), Gaps = 48/311 (15%) Query: 35 YEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 ++V++K++ G C+ D + T P +LGHE G V VG V K GDKV + Sbjct: 43 HDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVGVA 102 Query: 93 LFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTV 152 CGKC +C N NYC P D + C S V Sbjct: 103 SIIETCGKCEMCTNEVENYC-------PEAGSID-SNYGAC--------------SNIAV 140 Query: 153 VDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGC 212 ++EN V + PL+ + C T Y PG + GLGG+G A+ Sbjct: 141 INENFVIRWPENLPLDSGVPLLCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFA 200 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECI---NPQDYKKPIQEVLKEMTDGGVDFSFEV 269 KA GA + K K ++ GA + NP++ + G +D Sbjct: 201 KAFGAKVTVISSSLKKKREAFEKFGADSFLVSSNPEEMQG---------AAGTLD----- 246 Query: 270 IGRLDTM-----MASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFK 324 G +DT+ + LL + G +I+G P + P LL+ G+ + G K Sbjct: 247 -GIIDTIPGNHSLEPLLALLKPLGKLIILGAPEMPFEVPA-PSLLMGGKVMAASTAGSMK 304 Query: 325 SKEGIPKLVAD 335 + + + A+ Sbjct: 305 EIQEMIEFAAE 315 >1YQX-A nrPDB Length = 366 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 79/307 (25%), Positives = 122/307 (39%), Gaps = 30/307 (9%) Query: 36 EVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +VR K++ G+C +D H + + + P++ GHE G V VG V V GDKV + Sbjct: 43 DVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVGVGC 102 Query: 94 FTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV 153 C C C N NYC K L DGT + +S + V Sbjct: 103 LVGACHSCESCANDLENYCPKMIL-TYASIYHDGTITY-------------GGYSNHMVA 148 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCK 213 +E + + PL+ + C T Y PG + GLGG+G AV K Sbjct: 149 NERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVKFAK 208 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 A G+ + K K GA + +D QE ++ G +D + + + Sbjct: 209 AFGSKVTVISTSPSKKEEALKNFGADSFLVSRD-----QEQMQAAA-GTLDGIIDTVSAV 262 Query: 274 DTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTW-KGAVYGGFKSKEGIPKL 332 ++ L ++ G ++VG P + L + L+ GR G+ GG K + + Sbjct: 263 HPLLP-LFGLLKSHGKLILVGAP--EKPLELPAFSLIAGRKIVAGSGIGGMKETQEM--- 316 Query: 333 VADFMAK 339 DF AK Sbjct: 317 -IDFAAK 322 >1WLY-A nrPDB Length = 333 Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 80/285 (28%), Positives = 119/285 (41%), Gaps = 69/285 (24%) Query: 12 AAVLWEVKKP--FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL-----PV 64 AAV+ + P F E+V+V P +VR++ A+G+ D + +G + PL P+ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAG-IPHPLVVGEPPI 62 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124 ++G EAA +VE VG GVT G+ RVC CL P G Sbjct: 63 VVGFEAAAVVEEVGPGVTDFTVGE-------------RVCT------CLP-----PLG-- 96 Query: 125 QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGC---GFSTGY 181 +SQ + + K+ L+ V L G G + Y Sbjct: 97 ---------------------AYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQY 135 Query: 182 GSAVNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 KV PG + GG+G V + GA +I ++K A++LG Sbjct: 136 -LLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGAT-VIGTVSTEEKAETARKLGCHH 193 Query: 241 CIN--PQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLC 282 IN QD+ EV++E+T G GVD ++ IG+ DT+ SL C Sbjct: 194 TINYSTQDFA----EVVREITGGKGVDVVYDSIGK-DTLQKSLDC 233 >2CDC-A nrPDB Length = 366 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 10/122 (8%) Query: 23 SIEDVEVAPPKAY-EVRIKMVAVGICRTDDHVVSGNL-VTPLP-----VILGHEAAGIVE 75 ++DV+ +Y +++I+ + GIC D +V+G L ++ LP ++LGHEA G+VE Sbjct: 14 QVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKDFLVLGHEAIGVVE 73 Query: 76 SVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRG 135 G + GD V+P+ CG CR C ++C + G DG R Sbjct: 74 ESYHGFSQ---GDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKMDGFMREWWYD 130 Query: 136 KP 137 P Sbjct: 131 DP 132 >3QWB-A nrPDB Length = 334 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 68/261 (26%), Positives = 97/261 (37%), Gaps = 57/261 (21%) Query: 25 EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTV 84 ED V E+ IK G+ + + G P +LG EA+G V + G+GVT Sbjct: 26 EDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNF 85 Query: 85 KPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGT 144 + GD+V ++ Sbjct: 86 EVGDQV-------------------------------------------------AYISN 96 Query: 145 STFSQYT-VVDENAVAKIDAASPLEKVCLIGCGFS---TGYGSAVNVAKVTPGSTCAVFG 200 STF+QY+ + + V K+ + E++ L G T V G +F Sbjct: 97 STFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFA 156 Query: 201 L-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 GGVGL K GA IAV +K AKE GA IN + +++VLK Sbjct: 157 AAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLKFTN 214 Query: 260 DGGVDFSFEVIGRLDTMMASL 280 GVD SF+ +G+ DT SL Sbjct: 215 GKGVDASFDSVGK-DTFEISL 234 >1YB5-A nrPDB Length = 351 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 84/383 (21%), Positives = 156/383 (40%), Gaps = 66/383 (17%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSIE---DVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN 57 M+T K+++ A ++E P ++ D+ V PK ++V IK+ A G+ + ++ SG Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 LVTP--LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKN 115 LP G + AG++E+VG+ + K GD+V T G Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGG---------------- 124 Query: 116 DLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 +++Y + ++ V K+ ++ IG Sbjct: 125 -------------------------------YAEYALAADHTVYKLPEKLDFKQGAAIGI 153 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK 234 + T Y + ++ A V G + V G GGVGL+A +A G +I+ ++ Sbjct: 154 PYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVL 212 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + GA E N ++ I ++ K + + G+D E++ ++ L H G ++VG Sbjct: 213 QNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSH--GGRVIVVG 269 Query: 295 VPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMA--KKFSLDALITHVLP 352 + + INP + + V +KE + A A + L +I P Sbjct: 270 ---SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYP 326 Query: 353 FEKINEGFD-LLH-SGKSIRTVL 373 EK+ E + ++H SG + + +L Sbjct: 327 LEKVAEAHENIIHGSGATGKMIL 349 >1QOR-A nrPDB Length = 327 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%) Query: 21 PFSIEDVEVAP--PKAYEVRIKMVAVGICRTDDHVVSGNLVTP-LPVILGHEAAGIVESV 77 P ++ VE P P E++++ A+GI D ++ SG P LP LG EAAGIV V Sbjct: 13 PEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVSKV 72 Query: 78 GEGVTTVKPGDKVI 91 G GV +K GD+V+ Sbjct: 73 GSGVKHIKAGDRVV 86 Score = 34.3 bits (77), Expect = 0.093, Method: Compositional matrix adjust. Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 5/84 (5%) Query: 202 GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 GGVGL A KA G A++I K A + GA + IN ++ + + E LKE+T G Sbjct: 151 GGVGLIACQWAKALG-AKLIGTVGTAQKAQSALKAGAWQVINYRE--EDLVERLKEITGG 207 Query: 262 -GVDFSFEVIGRLDTMMASLLCCH 284 V ++ +GR DT SL C Sbjct: 208 KKVRVVYDSVGR-DTWERSLDCLQ 230 >5H83-A nrPDB Length = 360 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Query: 36 EVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V+ K++ G C D + + +T P ++GHE G+V +G V K GDKV + Sbjct: 41 DVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVGVGG 100 Query: 94 FTPQCGKCRVCKNPESNYCLK 114 F C KC +C N N C K Sbjct: 101 FVGACEKCEMCVNGVENNCSK 121 >3JYN-A nrPDB Length = 325 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 97/251 (38%), Gaps = 60/251 (23%) Query: 18 VKKPFSIEDVEVAP----PKAYEVRIKMVAVGICRTDDHVVSGNLVTP-LPVILGHEAAG 72 V P +E V+ P P+A VR K A+G+ D + SG P LP LG E AG Sbjct: 10 VGGPEVLEYVDFEPEAPGPQAVVVRNK--AIGLNFIDTYYRSGLYPAPFLPSGLGAEGAG 67 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 +VE+VG+ VT K GD+V P V PE+N Sbjct: 68 VVEAVGDEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANL--------------------- 106 Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 V D+ S + L+ G + Y +V P Sbjct: 107 -------------------------VKLADSVSFEQAAALMLKGLTVQY-LLRQTYQVKP 140 Query: 193 GSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KP 250 G GGVG A KA G A++I + +K A AK LGA E I DY + Sbjct: 141 GEIILFHAAAGGVGSLACQWAKALG-AKLIGTVSSPEKAAHAKALGAWETI---DYSHED 196 Query: 251 IQEVLKEMTDG 261 + + + E+TDG Sbjct: 197 VAKRVLELTDG 207 >3B70-A nrPDB Length = 371 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 84/362 (23%), Positives = 132/362 (36%), Gaps = 82/362 (22%) Query: 36 EVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFT 95 +V +++ AV I +D + G TP LG + AG V +VG VT ++ GD+V Sbjct: 38 QVYVRVEAVAINPSDTKM-RGQFATPW-AFLGTDYAGTVVAVGSDVTHIQVGDRV----- 90 Query: 96 PQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDE 155 Y +N++ C P FSQYTV Sbjct: 91 ---------------YGAQNEM---------------CPRTPDQ-----GAFSQYTVTRG 115 Query: 156 NAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV---------AKVTPGSTCAVFGL--GGV 204 AKI E+ + G ST G A+ + A P + V+ L GG Sbjct: 116 RVWAKIPKGLSFEQAAALPAGISTA-GLAMKLLGLPLPSPSADQPPTHSKPVYVLVYGGS 174 Query: 205 GLSAVMGCKAAGAARIIAVDI-NKDKFAKAKELGATECINPQDYKKP-IQEVLKEMTDGG 262 +A + + + I + + F AK GA E DY+ P + + ++ T Sbjct: 175 TATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVF---DYRAPNLAQTIRTYTKNN 231 Query: 263 VDFS-------------FEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL 309 + ++ F IGR SL E T +V + + ++ P + Sbjct: 232 LRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMV-----TTDWTLGPTIF 286 Query: 310 LTGRTWKGAVYGGFKSKEGIPKLVADF--MAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 G TW A YG S+E + D +A + D + H P + GFD + G Sbjct: 287 GEGSTWP-APYGRPGSEEER-QFGEDLWRIAGQLVEDGRLVH-HPLRVVQGGFDHIKQGM 343 Query: 368 SI 369 + Sbjct: 344 EL 345 >3WID-A nrPDB Length = 369 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 11/100 (11%) Query: 27 VEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLP-----VILGHEAAGIVESVGEG 80 +++ P+ YE ++K V +GIC TD V+G L T P ++LGHEA V V + Sbjct: 21 IDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDN 80 Query: 81 VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 +K GD V+PL + GKC C+ + C +G+P Sbjct: 81 -NYIKRGDFVVPLVR-RPGKCVNCRIGRQDNC---SIGDP 115 >3SLK-A nrPDB Length = 795 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 54/234 (23%), Positives = 84/234 (35%), Gaps = 67/234 (28%) Query: 17 EVKKPFSI-------EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHE 69 E +P S+ E AP EVRI M A G+ D + G + P LG E Sbjct: 214 EATRPGSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALG--MYPGVASLGSE 271 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTR 129 AG+V G GVT + PGD+V+ + G Sbjct: 272 GAGVVVETGPGVTGLAPGDRVMGMIPKAFGPL---------------------------- 303 Query: 130 RFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 V D V +I A + + F T Y + V++A Sbjct: 304 ---------------------AVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAG 342 Query: 190 VTPGSTCAVF-GLGGVGLSAVMGCKAAGAA--------RIIAVDINKDKFAKAK 234 + PG + V GGVG++A+ + GA + AV+++++ A ++ Sbjct: 343 LRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDKWQAVELSREHLASSR 396 >1Q1N-A nrPDB Length = 360 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 23/162 (14%) Query: 31 PPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVG-EGVTTVKPGD 88 P +++ IK+ A G+C +D H +G+ +P+++GHE G V +G + + +K G Sbjct: 30 PFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKVGQ 89 Query: 89 KV---IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHH-FLGT 144 +V +F+ C +C CKN YC T+ T +P ++ Sbjct: 90 RVGVGAQVFS--CLECDRCKNDNEPYC---------------TKFVTTYSQPYEDGYVSQ 132 Query: 145 STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 ++ Y V E+ V I P + CG T Y V Sbjct: 133 GGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVR 174 >4A27-A nrPDB Length = 349 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Query: 32 PKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTTVKPGDK 89 P+ E++I++ A G+ D V GN+ P P++ G E +GIVE++G+ V + GD+ Sbjct: 28 PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 87 Query: 90 VIPLFTPQCGKCRVCKNPESNYCLKNDL 117 V+ VC E Y + +D+ Sbjct: 88 VMAFVNYNAWAEVVCTPVEFVYKIPDDM 115 >3FBG-A nrPDB Length = 346 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 53/243 (21%), Positives = 93/243 (38%), Gaps = 62/243 (25%) Query: 19 KKPFSIED--------VEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEA 70 ++PF + D +++ PK +E+ +K+ ++ + D + V+ P +LG +A Sbjct: 9 EQPFKLSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD-VSKAPRVLGFDA 67 Query: 71 AGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRR 130 G+VESVG VT GD V +P Q+G+ Sbjct: 68 IGVVESVGNEVTMFNQGDIVYYSGSPD---------------------------QNGSN- 99 Query: 131 FTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKV 190 ++Y +++E VAK E+ + T Y + +V + Sbjct: 100 -----------------AEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFGI 142 Query: 191 T------PGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 + G T + G GGVG A KA G R+I + K++GA +N Sbjct: 143 SRNRNENEGKTLLIINGAGGVGSIATQIAKAYG-LRVITTASRNETIEWTKKMGADIVLN 201 Query: 244 PQD 246 ++ Sbjct: 202 HKE 204 >4RVS-A nrPDB Length = 329 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 32 PKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGV----TTVKPG 87 P E+ IK A+G+ D + SG LP ++G E G VE+VG GV T + G Sbjct: 26 PGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVG 85 Query: 88 DKVIPLFTPQCGKCRVCKNPES 109 D+V+ + C P S Sbjct: 86 DRVVSA-SANGAYAEFCTAPAS 106 >2WEK-A nrPDB Length = 341 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 8/133 (6%) Query: 141 FLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG 200 ++ +F++YTVV + + + P E + L+ G +T Y S + ++ G V Sbjct: 93 YMAPGSFAEYTVVPASIATPVPSVKP-EYLTLLVSG-TTAYISLKELGGLSEGKKVLVTA 150 Query: 201 L-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KPIQEVLKEM 258 GG G A+ K A +I + +K A K LG C P +YK +P+ VLK+ Sbjct: 151 AAGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLG---CDRPINYKTEPVGTVLKQE 206 Query: 259 TDGGVDFSFEVIG 271 GVD +E +G Sbjct: 207 YPEGVDVVYESVG 219 >4Y1B-A nrPDB Length = 425 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 83/387 (21%), Positives = 151/387 (39%), Gaps = 73/387 (18%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVIL--------------G 67 F E V+V P +V +K++A G+ + V L PL VI G Sbjct: 58 FRTEVVDVPPVGPGQVLVKVMAAGVNYNN---VWAALGEPLDVIAARQKQGATEDFHIGG 114 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 + +GIV +VG+GV +KPG +V+ L C+ ES ++ LG D Sbjct: 115 SDLSGIVWAVGDGV-RLKPGAEVVVL---------ACRWDESAQDIR--LG------ADP 156 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAV----AKIDAASPLEKVCLIGCGFSTGYGS 183 T R G +F+Q+ VVDE ++ A+ + + +G Sbjct: 157 VTSSTQRVWGYEENYG--SFAQFAVVDEYMCHPKPQRLSWAAASCYMATAATAYRQLFGW 214 Query: 184 AVNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 + V PG ++ G GG+G A+ + G +AV ++++ LGA I Sbjct: 215 EPHT--VRPGDPVLIWGGAGGLGSIAIQLVRHVGGI-PVAVVSSEERGEFCMRLGAKGWI 271 Query: 243 NPQDYKK-------PIQEVLKEMTDGGVDFS---FEVIGR------------LDTMMASL 280 + +++ +E +K+ DG F +EV+G DT+ S+ Sbjct: 272 DRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGADTIPTSI 331 Query: 281 LCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKK 340 A + G + ++ + + + R +G+ + I +L+ + Sbjct: 332 YMADNAGMVVICGGTTGYNGDVDLRFLWMRQKRL-QGSHAASAREAREITRLI-----DQ 385 Query: 341 FSLDALITHVLPFEKINEGFDLLHSGK 367 ++D ++ FE+I L+H + Sbjct: 386 GAIDPCLSRTFGFEEIGLAHQLIHDNQ 412 >3HZZ-A nrPDB Length = 467 Score = 37.0 bits (84), Expect = 0.013, Method: Compositional matrix adjust. Identities = 69/313 (22%), Positives = 118/313 (37%), Gaps = 66/313 (21%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124 I+G + AG+V G GV +PGD+V+ +CL +L +P G Sbjct: 138 IIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELESPDG-- 177 Query: 125 QDGTRRFTCRGKPIHHFLGTST----FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 D T P G T ++ +V N + E+ G ST Sbjct: 178 HDDTML-----DPEQRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTA 232 Query: 181 YGSAV--NVAKVTPGSTCAVFGL-GGVGLSAVMG--------------------CKAAGA 217 Y V N A + G ++G GG+G A C++ GA Sbjct: 233 YRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSPQKAEICRSMGA 292 Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM 276 II + KF K + +P+++K+ + ++E+T G +D FE GR +T Sbjct: 293 EAIIDRNAEGYKFWKDE-----HTQDPKEWKR-FGKRIRELTGGEDIDIVFEHPGR-ETF 345 Query: 277 MASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVAD- 335 AS+ + GT + N L ++ + G+ + ++ +L+A Sbjct: 346 GASVYVTRKG-GTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIAKG 404 Query: 336 ----FMAKKFSLD 344 ++K +SL+ Sbjct: 405 KIHPTLSKTYSLE 417 >4DVJ-A nrPDB Length = 363 Score = 36.2 bits (82), Expect = 0.025, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 64/214 (29%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124 ++G++AAGIV +VG VT +PGD+V Y G++ Sbjct: 84 VIGYDAAGIVSAVGPDVTLFRPGDEVF-------------------YA---------GSI 115 Query: 125 QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAK----ID----AASPLEKVCLIGCG 176 + T +++ +VDE V + +D AA PL + Sbjct: 116 -----------------IRPGTNAEFHLVDERIVGRKPKTLDWAEAAALPLTSITAWEAF 158 Query: 177 FSTGYGSAVNVAKVTPGSTCAVF---GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKA 233 F ++V K PG+ A+ G GGVG AV + +IA + Sbjct: 159 FDR-----LDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIATASRPETQEWV 213 Query: 234 KELGATECINPQDYKKPIQEVLKEMTDGGVDFSF 267 K LGA I D+ KP+ + + G F F Sbjct: 214 KSLGAHHVI---DHSKPLAAEVAALGLGAPAFVF 244 >6C49-A nrPDB Length = 350 Score = 35.8 bits (81), Expect = 0.028, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 21 PFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGE 79 P+ + E+ P ++V +K+ G+C +D V++ T PV+ GHE G + ++G Sbjct: 28 PYKFDAGELQP---HQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIVALGS 84 Query: 80 GVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDL 117 ++ G +V I C C C + C ++ Sbjct: 85 EAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENI 123 >4IDE-A nrPDB Length = 332 Score = 35.4 bits (80), Expect = 0.037, Method: Compositional matrix adjust. Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 26 DVEVAPP--KAYEVRIKMVAVGICRTDDHVVSG---NLVTPLPVILGHEAAGIVESVGEG 80 D VA P K +V IK+VA + D G + +PLP I G++ AG+V VG Sbjct: 42 DPSVAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQ 101 Query: 81 VTTVKPGDKV 90 VT K GD+V Sbjct: 102 VTKFKVGDEV 111 >3TQH-A nrPDB Length = 321 Score = 35.0 bits (79), Expect = 0.057, Method: Compositional matrix adjust. Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 66/254 (25%) Query: 48 RTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLF----TPQCGKCRV 103 R V+ L LP LG++ +G V +G V V GDKV+ + P C V Sbjct: 53 RNGSGFVAKKLKNNLPSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPCCYAEYV 112 Query: 104 CKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDA 163 C +P++ + K++ Sbjct: 113 CASPDT-----------------------------------------------IIQKLEK 125 Query: 164 ASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIA 222 S L+ L G + A+N A+V G + G GGVG A+ K G I Sbjct: 126 LSFLQAASLPTAGLTAL--QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKGTTVITT 183 Query: 223 VDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLC 282 F KA LGA +CIN + ++ L ++ VD +++G D + S+ C Sbjct: 184 ASKRNHAFLKA--LGAEQCINYHE-----EDFLLAIST-PVDAVIDLVGG-DVGIQSIDC 234 Query: 283 CHEACGTSVIVGVP 296 E T IV VP Sbjct: 235 LKE---TGCIVSVP 245 >2OBY-A nrPDB Length = 338 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 7/127 (5%) Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206 +QY V E + I L + I + T + V V G + GL GVG Sbjct: 102 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 161 Query: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264 +A+ + AGA ++ K K A++LGA N YKK + LK GV+ Sbjct: 162 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 217 Query: 265 FSFEVIG 271 + IG Sbjct: 218 LILDCIG 224 >4J6F-A nrPDB Length = 382 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 17/88 (19%) Query: 25 EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP-----------------LPVILG 67 DV V P A EV IK+ A G+ TD V G T P I G Sbjct: 52 RDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLTFPRIQG 111 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFT 95 + G + +VGEGV + G++V+ F+ Sbjct: 112 TDTVGHIVAVGEGVDRARIGERVMVDFS 139 >5A3V-A nrPDB Length = 329 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 6/75 (8%) Query: 26 DVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL-----PVILGHEAAGIVESVGEG 80 V V PK+ EV +K+ A + D + G ++ P P I + AG V VG G Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKG-MIRPFLPRKFPCIPATDVAGEVVEVGSG 83 Query: 81 VTTVKPGDKVIPLFT 95 V K GDKV+ + + Sbjct: 84 VKNFKAGDKVVAVLS 98 >2VWH-A nrPDB Length = 357 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 8/66 (12%) Query: 32 PKAYEVRIKMVAVGICRTDDHVVSGNLVTPLP-----VILGHEAAGIVESVGEGVTTVKP 86 P++ E ++ + VG+ TD V++G P ++LGHEA G+V V T ++ Sbjct: 23 PESGEALVRTLRVGVDGTDHEVIAGGH-GGFPEGEDHLVLGHEAVGVV--VDPNDTELEE 79 Query: 87 GDKVIP 92 GD V+P Sbjct: 80 GDIVVP 85 >2CF5-A nrPDB Length = 357 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 83/345 (24%), Positives = 138/345 (40%), Gaps = 33/345 (9%) Query: 21 PFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGE 79 P++ E P +V I+++ GIC TD H +L ++ P++ GHE G V VG Sbjct: 24 PYTYTLRETGPE---DVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEVVEVGS 80 Query: 80 GVTTVKPGD-KVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPI 138 V+ GD + CG C C+ YC K G+P Sbjct: 81 DVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIW---------SYNDVYINGQPT 131 Query: 139 HHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAV 198 F++ TVV + V KI +E+ + C T Y + PG + Sbjct: 132 Q-----GGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGI 186 Query: 199 FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 GLGGVG V KA G + NK + ++LGA + + D K + E+ Sbjct: 187 LGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAK-----MSEL 241 Query: 259 TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGA 318 D +D+ + + + + L + G +++GV + P+L+L + G+ Sbjct: 242 AD-SLDYVIDTVP-VHHALEPYLSLLKLDGKLILMGVINNPLQF-LTPLLMLGRKVITGS 298 Query: 319 VYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 G K E + + K+ L ++I V+ + +N F+ L Sbjct: 299 FIGSMKETEEMLEF-----CKEKGLSSII-EVVKMDYVNTAFERL 337 >4KPA-A nrPDB Length = 494 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 22/42 (52%) Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 KP+Q ++K + G F FE GR+ ++S EAC S Sbjct: 48 KPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDES 89 >6ACF-A nrPDB Length = 367 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 G AV G+G V GA ++I DINK+ A+A E + ++P D Sbjct: 173 GKVVAVQGVGNVAYHLCRHLHEEGA-KLIVTDINKEAVARAVEEFGAKAVDPND 225 >2VN8-A nrPDB Length = 375 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 77/316 (24%), Positives = 111/316 (35%), Gaps = 68/316 (21%) Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 P+ LG + +G+V G V KPGD+V P + Sbjct: 94 FPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW----------------------KQ 131 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTL + G + H + T +Q A+ L V L Sbjct: 132 GTLSEFV---VVSGNEVSHKPKSLTHTQ--------------AASLPYVALTAWSAINKV 174 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G +N T + GGVG A+ KA A + AV ++D ++LGA + Sbjct: 175 G-GLNDKNCTGKRVLILGASGGVGTFAIQVMKAWD-AHVTAV-CSQDASELVRKLGADDV 231 Query: 242 INPQDYKK-PIQEVLKEMTDGGVDFSFEVI-GRLDTMMASLLCCHEACGTSVIVGVPPAS 299 I DYK ++E LK + DF + + G +T L + G + + V P Sbjct: 232 I---DYKSGSVEEQLKSLKP--FDFILDNVGGSTETWAPDFL--KKWSGATYVTLVTPFL 284 Query: 300 QN---LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDAL---------- 346 N L I +L TG T F +G+ A FMA LD + Sbjct: 285 LNMDRLGIADGMLQTGVTVGSKALKHF--WKGVHYRWAFFMASGPCLDDIAELVDAGKIR 342 Query: 347 --ITHVLPFEKINEGF 360 I PF K+ E F Sbjct: 343 PVIEQTFPFSKVPEAF 358 >1JGT-A nrPDB Length = 513 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 31/127 (24%), Positives = 49/127 (38%), Gaps = 20/127 (15%) Query: 135 GKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194 G + H T S+ + + AVA + AA LEK +VTPG Sbjct: 200 GTAVTHRTWTPGLSRRILPEGEAVAAVRAA--LEKAV---------------AQRVTPGD 242 Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKD---KFAKAKELGATECINPQDYKKPI 251 T V GG+ S V C A + V + D +F +A+ + ++ P Sbjct: 243 TPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIPT 302 Query: 252 QEVLKEM 258 E+L ++ Sbjct: 303 TELLAQL 309 >1V9L-A nrPDB Length = 421 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 7/63 (11%) Query: 177 FSTGYGSAVNVAKVT-------PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK 229 ++TG+G AV ++ G T A+ G+G VG + GA I DIN Sbjct: 187 YATGFGVAVATREMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVA 246 Query: 230 FAK 232 + K Sbjct: 247 YRK 249 >5ILO-A nrPDB Length = 271 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 12/82 (14%) Query: 200 GLGGVGLSAVMGCKAAGAARIIAVDI--NKDKFAKAKELGATECI--------NPQDYKK 249 G GG+GL AAGAA++ +D+ N ++F K + T+ + N + + Sbjct: 23 GAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEA 82 Query: 250 PIQEVLKEMTDGGVDFSFEVIG 271 +E+ K T G +D V G Sbjct: 83 TYEEIAK--TFGNIDIVVNVAG 102 >2B25-A nrPDB Length = 336 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 24/51 (47%) Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 +++ + PG T G G G+S + R+I+ ++ KD AK+ Sbjct: 98 LSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK 148 >1V3V-A nrPDB Length = 333 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 68/155 (43%), Gaps = 26/155 (16%) Query: 142 LGTSTFSQYTVVDENAVAKIDAASPLEKVCL------IGCGFSTGYGSAVNVAKVTPGST 195 L S ++ + + D + K+ P +K+ L IG T Y + V V G T Sbjct: 90 LAQSGWTTHFISDGKGLEKLLTEWP-DKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGET 148 Query: 196 CAV-FGLGGVG-----LSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK- 248 V G VG ++ + GCK GAA + +K A K++G N YK Sbjct: 149 VLVSAAAGAVGSVVGQIAKLKGCKVVGAAG------SDEKIAYLKQIGFDAAFN---YKT 199 Query: 249 -KPIQEVLKEMTDGGVDFSFEVIG--RLDTMMASL 280 ++E LK+ + G D F+ +G L+T+++ + Sbjct: 200 VNSLEEALKKASPDGYDCYFDNVGGEFLNTVLSQM 234 >1NBW-A nrPDB Length = 607 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 142 LGTSTFSQYTVVDENAVAKIDAASPLEKVCLI 173 L + F++ + E + ID ASPLEK+ L+ Sbjct: 491 LSPAVFAKVVYIKEGELVPIDNASPLEKIRLV 522 >4A10-A nrPDB Length = 447 Score = 27.7 bits (60), Expect = 9.4, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 17/27 (62%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVI 91 +LG + +G+V G GV KPGD VI Sbjct: 112 VLGSDCSGVVVRTGIGVRRWKPGDHVI 138 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1HSZ-A nrPDB 513 e-146 1HSO-A nrPDB 507 e-144 1U3W-A nrPDB 506 e-144 1EE2-A nrPDB 478 e-135 1D1T-A nrPDB 445 e-125 3COS-A nrPDB 445 e-125 1MC5-A nrPDB 436 e-123 4DLA-A nrPDB 434 e-122 4JJI-A nrPDB 429 e-121 1CDO-A nrPDB 426 e-120 4RQU-A nrPDB 419 e-118 1E3E-A nrPDB 418 e-117 1P0F-A nrPDB 404 e-113 3PII-A nrPDB 310 5e-85 5TNX-A nrPDB 303 1e-82 1F8F-A nrPDB 301 4e-82 3MEQ-A nrPDB 300 9e-82 4Z6K-A nrPDB 298 2e-81 1LLU-A nrPDB 291 4e-79 2DFV-A nrPDB 289 1e-78 3S2F-A nrPDB 289 2e-78 3GFB-A nrPDB 278 2e-75 2EER-A nrPDB 277 4e-75 6N7L-A nrPDB 272 1e-73 1PL8-A nrPDB 271 4e-73 2DQ4-A nrPDB 269 2e-72 3QE3-A nrPDB 269 2e-72 4CPD-A nrPDB 268 2e-72 5KIA-A nrPDB 266 7e-72 4EEZ-A nrPDB 257 7e-69 1R37-A nrPDB 253 9e-68 5YLN-A nrPDB 251 4e-67 5VM2-A nrPDB 250 8e-67 1H2B-A nrPDB 249 1e-66 4OH1-A nrPDB 247 7e-66 5ENV-A nrPDB 245 2e-65 1YKF-A nrPDB 243 7e-65 1E3J-A nrPDB 241 4e-64 4EJ6-A nrPDB 240 8e-64 1UUF-A nrPDB 239 1e-63 5H82-A nrPDB 238 3e-63 3FSR-A nrPDB 236 8e-63 3FPC-A nrPDB 234 6e-62 3FPL-A nrPDB 233 7e-62 3TWO-A nrPDB 232 2e-61 4GKV-A nrPDB 230 8e-61 5YAT-A nrPDB 229 1e-60 1KEV-A nrPDB 226 9e-60 3M6I-A nrPDB 226 1e-59 5K1S-A nrPDB 224 4e-59 4ILK-A nrPDB 224 4e-59 4OAQ-A nrPDB 223 1e-58 1YQX-A nrPDB 223 1e-58 2H6E-A nrPDB 223 1e-58 5Z0C-A nrPDB 222 2e-58 6DKH-A nrPDB 216 1e-56 4UEJ-A nrPDB 214 4e-56 3IP1-A nrPDB 211 4e-55 6FG0-A nrPDB 210 9e-55 5FI5-A nrPDB 208 3e-54 2OUI-A nrPDB 207 5e-54 1YB5-A nrPDB 203 9e-53 5VKT-A nrPDB 199 2e-51 3UOG-A nrPDB 196 1e-50 5H83-A nrPDB 195 2e-50 3WLE-A nrPDB 183 1e-46 1Q1N-A nrPDB 182 3e-46 2DPH-A nrPDB 180 9e-46 3QWB-A nrPDB 178 3e-45 4JLW-A nrPDB 176 1e-44 1WLY-A nrPDB 176 2e-44 1KOL-A nrPDB 167 9e-42 1QOR-A nrPDB 159 3e-39 4RVS-A nrPDB 157 8e-39 2VCY-A nrPDB 155 3e-38 3FBG-A nrPDB 148 5e-36 3JYN-A nrPDB 147 8e-36 3B70-A nrPDB 142 2e-34 4A27-A nrPDB 129 3e-30 3SLK-A nrPDB 128 4e-30 2CDC-A nrPDB 118 5e-27 3WID-A nrPDB 100 1e-21 Sequences not found previously or not previously below threshold: 6C49-A nrPDB 168 3e-42 2CF5-A nrPDB 152 2e-37 2OBY-A nrPDB 137 7e-33 3HZZ-A nrPDB 135 3e-32 4J6F-A nrPDB 131 5e-31 4A10-A nrPDB 124 7e-29 3TQH-A nrPDB 122 2e-28 4DVJ-A nrPDB 119 2e-27 4Y1B-A nrPDB 119 3e-27 2VN8-A nrPDB 118 4e-27 4IDE-A nrPDB 116 2e-26 2WEK-A nrPDB 112 2e-25 5A3V-A nrPDB 110 8e-25 4EYE-A nrPDB 109 2e-24 2VWH-A nrPDB 100 8e-22 5LB9-A nrPDB 83 2e-16 1V3V-A nrPDB 82 3e-16 2Y05-A nrPDB 76 2e-14 5GXF-A nrPDB 76 4e-14 1O89-A nrPDB 71 7e-13 2J3K-A nrPDB 63 2e-10 2VNA-A nrPDB 58 6e-09 2ZB3-A nrPDB 54 1e-07 1ZCJ-A nrPDB 44 1e-04 3ZWA-A nrPDB 43 3e-04 4DIO-A nrPDB 43 3e-04 5ILO-A nrPDB 42 5e-04 2EGU-A nrPDB 42 5e-04 3MGG-A nrPDB 41 0.001 2VHY-A nrPDB 40 0.002 1XLT-A nrPDB 39 0.004 1X14-A nrPDB 39 0.005 2B25-A nrPDB 39 0.005 3X2F-A nrPDB 37 0.009 6BII-A nrPDB 37 0.010 5JE5-A nrPDB 37 0.013 5EKU-A nrPDB 37 0.016 1VH3-A nrPDB 37 0.019 1V8B-A nrPDB 36 0.021 4XIJ-A nrPDB 36 0.022 4M36-A nrPDB 36 0.024 1BW9-B nrPDB 36 0.024 2YVG-A nrPDB 36 0.025 5X7F-A nrPDB 36 0.026 3VPX-A nrPDB 36 0.030 6BQC-A nrPDB 36 0.030 6ACF-A nrPDB 35 0.046 5Z1Z-A nrPDB 35 0.047 1V9L-A nrPDB 35 0.047 4K2X-A nrPDB 35 0.048 6IQV-A nrPDB 35 0.049 4FS8-A nrPDB 35 0.066 6C55-A nrPDB 35 0.067 5VMT-A nrPDB 35 0.073 4CUK-A nrPDB 34 0.093 1W1U-A nrPDB 34 0.099 2O23-A nrPDB 34 0.11 1EUF-A nrPDB 34 0.11 1DXY-A nrPDB 34 0.11 1I9G-A nrPDB 34 0.12 4N7R-A nrPDB 34 0.13 3D2L-A nrPDB 34 0.13 1JWB-B nrPDB 34 0.13 4COO-A nrPDB 34 0.14 1M54-A nrPDB 34 0.15 3EGI-A nrPDB 34 0.15 3GDH-A nrPDB 34 0.15 5JXW-A nrPDB 34 0.15 5F8E-A nrPDB 34 0.16 5MMS-A nrPDB 34 0.16 2EEZ-A nrPDB 34 0.16 2ZJ1-A nrPDB 33 0.18 1E3W-A nrPDB 33 0.18 2EKL-A nrPDB 33 0.19 5JJC-A nrPDB 33 0.19 5AOV-A nrPDB 33 0.19 4WJI-A nrPDB 33 0.20 1CYD-A nrPDB 33 0.21 4AEC-A nrPDB 33 0.21 4GCM-A nrPDB 33 0.23 3KYD-B nrPDB 33 0.23 3KYC-B nrPDB 33 0.23 2ISQ-A nrPDB 33 0.25 5D84-A nrPDB 33 0.25 4OM8-A nrPDB 33 0.27 6FZI-A nrPDB 33 0.29 4DIB-A nrPDB 33 0.29 3G1U-A nrPDB 33 0.29 5U9P-A nrPDB 32 0.33 3JTJ-A nrPDB 32 0.40 3ZZN-A nrPDB 32 0.41 1ZFN-A nrPDB 32 0.42 4XGI-A nrPDB 32 0.43 2HMT-A nrPDB 32 0.45 5BUT-A nrPDB 32 0.49 1NVM-B nrPDB 32 0.56 5TQV-A nrPDB 32 0.59 1GPJ-A nrPDB 32 0.60 5VJ7-A nrPDB 32 0.65 1XDW-A nrPDB 32 0.65 3AOE-A nrPDB 31 0.66 3EMK-A nrPDB 31 0.68 4K28-A nrPDB 31 0.69 3TNL-A nrPDB 31 0.72 4J90-A nrPDB 31 0.74 3BKX-A nrPDB 31 0.74 3FBT-A nrPDB 31 0.77 4YRY-B nrPDB 31 0.78 3F9I-A nrPDB 31 0.79 4PZE-A nrPDB 31 0.80 5OHX-A nrPDB 31 0.84 6J0Z-C nrPDB 31 0.86 3HM2-A nrPDB 31 0.93 1QO8-A nrPDB 31 0.93 4RS3-A nrPDB 31 0.94 1VE9-A nrPDB 31 0.98 6DLL-A nrPDB 31 1.0 3GDF-A nrPDB 31 1.1 2HAE-A nrPDB 31 1.1 5UJU-A nrPDB 30 1.1 4TXK-A nrPDB 30 1.1 2BRY-A nrPDB 30 1.1 6GME-A nrPDB 30 1.1 2WWR-A nrPDB 30 1.2 4MOP-A nrPDB 30 1.2 5NMX-A nrPDB 30 1.2 5ZBK-A nrPDB 30 1.2 5UYY-A nrPDB 30 1.2 3X43-A nrPDB 30 1.3 3NJ4-A nrPDB 30 1.3 1LTH-T nrPDB 30 1.3 6GBN-A nrPDB 30 1.4 5MH6-A nrPDB 30 1.4 1WG8-A nrPDB 30 1.4 5FUB-A nrPDB 30 1.5 1HL3-A nrPDB 30 1.6 1DOD-A nrPDB 30 1.6 3DOC-A nrPDB 30 1.7 2AS0-A nrPDB 30 1.7 5J9G-A nrPDB 30 1.8 4DIM-A nrPDB 30 1.8 2X36-A nrPDB 30 1.8 3OND-A nrPDB 30 1.9 3DC2-A nrPDB 30 1.9 6HNS-A nrPDB 30 1.9 4LMA-A nrPDB 30 2.0 2EFY-A nrPDB 30 2.0 4IZO-A nrPDB 30 2.1 3HDH-A nrPDB 30 2.1 5M0P-A nrPDB 30 2.1 3HWR-A nrPDB 30 2.3 2RIR-A nrPDB 30 2.3 4P4L-A nrPDB 30 2.4 3WGE-A nrPDB 30 2.4 3PPI-A nrPDB 30 2.4 3JTM-A nrPDB 29 2.5 1F14-A nrPDB 29 2.6 3AOE-E nrPDB 29 2.8 1YPF-A nrPDB 29 2.8 6APH-A nrPDB 29 2.9 1W7I-A nrPDB 29 3.0 3OC4-A nrPDB 29 3.1 3LLV-A nrPDB 29 3.1 6ABI-A nrPDB 29 3.1 3OJO-A nrPDB 29 3.3 2E28-A nrPDB 29 3.4 1MV8-A nrPDB 29 3.5 1G6Q-1 nrPDB 29 3.7 1FI8-A nrPDB 29 3.7 5JFC-L nrPDB 29 3.7 3H9U-A nrPDB 29 3.7 2YU3-A nrPDB 29 3.8 2DK5-A nrPDB 29 3.8 3T4P-A nrPDB 29 3.9 5XW3-A nrPDB 29 3.9 1OBF-O nrPDB 29 4.0 1S4D-A nrPDB 29 4.1 1B26-A nrPDB 29 4.2 5J46-A nrPDB 29 4.2 3FEO-A nrPDB 29 4.2 4LMB-A nrPDB 29 4.3 3RHA-A nrPDB 29 4.3 1ZEJ-A nrPDB 29 4.4 1LSS-A nrPDB 29 4.7 1V9C-A nrPDB 29 4.7 3EUW-A nrPDB 29 4.8 3GRP-A nrPDB 29 4.8 3GNQ-A nrPDB 29 5.0 3NNK-A nrPDB 29 5.2 4RDI-A nrPDB 29 5.2 4F86-A nrPDB 29 5.3 4ZV2-A nrPDB 28 5.6 6JCV-A nrPDB 28 5.9 4X28-D nrPDB 28 5.9 4EJ0-A nrPDB 28 6.0 4GBJ-A nrPDB 28 6.2 3LP6-A nrPDB 28 6.4 1V7L-A nrPDB 28 6.5 3T5Y-A nrPDB 28 7.0 4E4T-A nrPDB 28 7.1 1KON-A nrPDB 28 7.2 6DHM-A nrPDB 28 7.8 1LU9-A nrPDB 28 7.8 3GG9-A nrPDB 28 7.8 1ZVF-A nrPDB 28 8.4 5YEI-C nrPDB 28 8.5 2YY8-A nrPDB 28 8.5 4V68-BC nrPDB 28 9.3 4D3F-A nrPDB 28 9.4 3BA1-A nrPDB 27 9.9 2AG5-A nrPDB 27 9.9 >1HSZ-A nrPDB Length = 374 Score = 513 bits (1322), Expect = e-146, Method: Composition-based stats. Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 300 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTVLTF 375 LLHSGKSIRTVLTF Sbjct: 361 LLHSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 507 bits (1305), Expect = e-144, Method: Composition-based stats. Identities = 350/374 (93%), Positives = 362/374 (96%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVAVGIC TDDHVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCR+CKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 120 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTCR KPIHHFLG STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSA+MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLLTGRTWKGA+ GGFKSKE +PKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTVLTF 375 LLHSGKSIRT+L F Sbjct: 361 LLHSGKSIRTILMF 374 >1U3W-A nrPDB Length = 374 Score = 506 bits (1303), Expect = e-144, Method: Composition-based stats. Identities = 354/374 (94%), Positives = 366/374 (97%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVA GICR+D+HVVSGNLVTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR+CKNPESNYCLKNDLGNPR Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTRRFTC GKPIHHF+G STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS VMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIG+LDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSINPMLLLTGRTWKGA++GGFKSKE +PKLVADFMAKKFSLDALIT+VLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTVLTF 375 LL SGKSIRTVLTF Sbjct: 361 LLRSGKSIRTVLTF 374 >1EE2-A nrPDB Length = 373 Score = 478 bits (1229), Expect = e-135, Method: Composition-based stats. Identities = 323/374 (86%), Positives = 347/374 (92%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 STAGKVIKCKAAVLWE KKPFSIE+VEVAPPKA+EVRIKMVA GICR+DDHVVSG LV P Sbjct: 1 STAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPVI GHEAAGIVES+GEGVTTV+PGDKVIPLF PQCGKC VCK+PE N CLKN L PR Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKN-LSMPR 119 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GT+QDGT RFTCRGKPIHHFLGTSTFSQYTVVDE +VAKIDAASPLEKVCL+GCGFSTGY Sbjct: 120 GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY 179 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVT GSTCAVFGLGGVGLS +MGCKAAGAARII VDINKDKFAKAKE+GATEC Sbjct: 180 GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 +NPQDYKKPIQEVL EM++GGVDFSFEVIGRLDTM+A+L CC EA G SVIVGVPP SQN Sbjct: 240 VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN 299 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLL+GRTWKGA++GGFKSK+ +PKLVADFMAKKF+LD LITHVLPFEKINEGFD Sbjct: 300 LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD 359 Query: 362 LLHSGKSIRTVLTF 375 LL SGKSIRT+LTF Sbjct: 360 LLRSGKSIRTILTF 373 >1D1T-A nrPDB Length = 373 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 260/374 (69%), Positives = 315/374 (84%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 TAGKVIKCKAAVLWE K+PFSIE++EVAPPK EVRIK++A GICRTDDHV+ G +V+ Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ R Sbjct: 61 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDI-TGR 119 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 G L DGT RFTC+GKP+HHFL TSTF++YTVVDE++VAKID A+P EKVCLIGCGFSTGY Sbjct: 120 GVLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGY 179 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G+AV KV PGSTC VFGLGGVGLS +MGCK+AGA+RII +D+NKDKF KA +GATEC Sbjct: 180 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 I+P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP+++ Sbjct: 240 ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKM 299 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 L+ +PMLL TGRTWKG V+GG KS++ +PKLV +F+AKKF LD LITHVLPF+KI+EGF+ Sbjct: 300 LTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 359 Query: 362 LLHSGKSIRTVLTF 375 LL+SG+SIRTVLTF Sbjct: 360 LLNSGQSIRTVLTF 373 >3COS-A nrPDB Length = 381 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 227/380 (59%), Positives = 284/380 (74%), Gaps = 5/380 (1%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-V 59 M T GKVIKCKAA+ WE KP IE+VEVAPPKA+EVRI+++A +C TD V+ Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 60 TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDL-- 117 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 118 --GNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 + + ++D T RFTC+GKP++HF GTSTFSQYTVV + +AKID + LE+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 GFSTGYG+A+N AKVTPGSTCAVFGLGGVGLSAVMGCKAAGA+RII +DIN +KF KAK Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 296 PPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEK 355 S+ L++ P L+ GRT G +GG+KS + IPKLV D+ KKF+LDAL+TH LPF+K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 356 INEGFDLLHSGKSIRTVLTF 375 I+E FDL++ GKSIRT+L F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1MC5-A nrPDB Length = 374 Score = 436 bits (1121), Expect = e-123, Method: Composition-based stats. Identities = 233/371 (62%), Positives = 292/371 (78%), Gaps = 1/371 (0%) Query: 4 AGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP-L 62 A +VIKCKAAV WE KP SIE++EVAPPKA+EVRIK++A +C TD + +SG Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG 122 PVILGHE AGIVESVGEGVT +K GD VIPL+ PQCG+C+ C NP++N C K + +G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 123 TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + DGT RFTC+GK I H++GTSTFS+YTVV + +VAKID +PL+KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AVN AK+ PGS CAVFGLGGVGL+ +MGCK AGA+RII VDINKDKFA+AKE GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 NPQD+ KPIQEVL EMTDGGVD+SFE IG + M A+L CH+ G SV+VGV + + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 + P L+TGRTWKG +GG+KS E +PKLV+++M+KK +D +TH L F++IN+ F+L Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 363 LHSGKSIRTVL 373 +HSGKSIRTV+ Sbjct: 362 MHSGKSIRTVV 372 >4DLA-A nrPDB Length = 396 Score = 434 bits (1116), Expect = e-122, Method: Composition-based stats. Identities = 201/376 (53%), Positives = 261/376 (69%), Gaps = 2/376 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 +T G+VI CKAAV WE KP IEDV+VAPP+A EVR+K++ +C TD + SG Sbjct: 19 ATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEG 78 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 L P +LGHEAAGIVESVGEGVT V+PGD VIP + +C +C+ CK+ ++N C K Sbjct: 79 LFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATG 138 Query: 121 RGTLQ-DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ GKPI+HF+GTSTFSQYTVV + +VAKID +PLEKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS AVFGLG VGL+ G KAAGA+RII +DI+ KF +AK G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 E INP+++++PIQ+V+ ++TDGGVD+SFE IG + M ++L CCH+ GTSVIVGV + Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG +GGFKS+ +P LV ++ K+ +D ITH + IN+ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 360 FDLLHSGKSIRTVLTF 375 FDL+H G +R VL Sbjct: 379 FDLMHDGDCLRVVLDM 394 >4JJI-A nrPDB Length = 378 Score = 429 bits (1104), Expect = e-121, Method: Composition-based stats. Identities = 202/375 (53%), Positives = 258/375 (68%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 +T G+VI CKAAV +E KP IEDV+VAPP+A EVRIK++ +C TD + SG Sbjct: 1 ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 60 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 L P ILGHEAAGIVESVGEGVT V+ GD VIP + +C +C+ CK+ ++N C K Sbjct: 61 LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 120 Query: 121 RGTLQ-DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D RF+ GKPI+HF+GTSTFSQYTVV + +VAKID +PL+KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS A+FGLG VGL+ G K AGA+RII +DI+ K+ AK+ G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 E +NP+D+ KPIQEV+ ++TDGGVD+SFE IG + M A+L CCH+ GTSVIVGV + Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG +GGFKS+ +P LV +M K+ +D ITH L +IN+ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 360 FDLLHSGKSIRTVLT 374 FDLLH G +R VL Sbjct: 361 FDLLHEGTCLRCVLD 375 >1CDO-A nrPDB Length = 374 Score = 426 bits (1095), Expect = e-120, Method: Composition-based stats. Identities = 208/375 (55%), Positives = 270/375 (72%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDD-HVVSGNLVT 60 +T GKVIKCKAAV WE KP IE++EV P A E+RIK++A G+C TD H+ G Sbjct: 1 ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 PV+LGHE AGIVESVG GVT +PG+KVIPLF QCG+CR C++P++N C+K Sbjct: 61 GFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANES 120 Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 + RFTC+G+ + FLGTSTFSQYTVV++ AVAKID ++PL+ VCL+GCG STG Sbjct: 121 PDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTG 180 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +G+AVN AKV PGSTCAVFGLG VGL+AVMGC +AGA RIIAVD+N DKF KAK GAT+ Sbjct: 181 FGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATD 240 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 +NP D+ +PI +VL +MT+GGVDFS E +G + M +L C + G SV+VG Sbjct: 241 FVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWT-DLH 299 Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 +++ P+ L+ GRTWKG+++GGFK K+G+PK+V ++ KK LD ITH +P E +N+ Sbjct: 300 DVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAI 359 Query: 361 DLLHSGKSIRTVLTF 375 DL+ GK IRTVL+ Sbjct: 360 DLMKHGKCIRTVLSL 374 >4RQU-A nrPDB Length = 375 Score = 419 bits (1077), Expect = e-118, Method: Composition-based stats. Identities = 190/372 (51%), Positives = 250/372 (67%), Gaps = 2/372 (0%) Query: 6 KVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL-PV 64 ++I+CKAAV WE KP IE+VEVAPP+ +EVRIK++ +C TD + TPL P Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124 I GHEA GIVESVGEGVT ++PGD V+P+FT +CG+CR C + ESN C + RG + Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 125 -QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 DG RF+ GKPI+HFLGTSTFS+YTVV VAKI+ +PL+KVC++ CG STG G+ Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 +NVAK G + A+FGLG VGL A G + AGA+RII VD N +F +AKE G TEC+N Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLS 303 P+D+ KPIQ+V+ EMTDGGVD S E G + M+ + C H+ G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 304 INPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 +PM L RT KG +G +K K IP +V +M K+ L+ ITH +PF +IN+ FD + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 364 HSGKSIRTVLTF 375 G+SIR ++T Sbjct: 362 LKGESIRCIITM 373 >1E3E-A nrPDB Length = 376 Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats. Identities = 201/378 (53%), Positives = 267/378 (70%), Gaps = 6/378 (1%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 T GKVIKCKAA+ W+ P IE++EV+PPKA EVRI+++A +C TD + Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDL---- 117 PV+LGHE AGIVESVG GVT KPGDKVIP F PQC +C++C +P +N C K Sbjct: 61 FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYP 120 Query: 118 GNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 177 + ++D T RFTC+G+ I+HF+G S+FSQYTVV E +A++D + LE+VCLIGCGF Sbjct: 121 TIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGF 180 Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 S+GYG+A+N AKVTPGSTCAVFGLG VGLSA++GCK AGA+RIIA+DIN +KF KAK LG Sbjct: 181 SSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALG 240 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 AT+C+NP++ KP+Q+V+ E+T GGVD+S + G T+ A++ C G+ +VG Sbjct: 241 ATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKV 300 Query: 298 ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKIN 357 + ++L GR+ G +GG+KS + +P LV+D+ KKF LD L+TH LPFE IN Sbjct: 301 DEMTIPTVDVIL--GRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIN 358 Query: 358 EGFDLLHSGKSIRTVLTF 375 + DL+ GKSIRT+LTF Sbjct: 359 DAIDLMKEGKSIRTILTF 376 >1P0F-A nrPDB Length = 373 Score = 404 bits (1037), Expect = e-113, Method: Composition-based stats. Identities = 221/375 (58%), Positives = 289/375 (77%), Gaps = 2/375 (0%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVT 60 M TAGK I CKAAV WE KP S+E + VAPPKA+EVRIK++A GIC +D V+ + + Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 PVILGHEA G+VES+G GVT VKPGDKVIPLF PQCG CR CK+ SN+C KND+G Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + D T RFTCRGKPI++ +GTSTF++YTVV + AVAKID +PLE CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AVN AKVTPGSTCAVFGLGGVG SA++GCKAAGA+RII V +KDKF KA ELGATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 C+NP+DY KPI EV+ E T+GGVD++ E GR++TMM +L + G +V++G+ ++ Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 L ++P+LLLTGR+ KG+V+GGFK E + +LV D+M KK +++ L++ L ++IN+ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 361 DLLHSGKSIRTVLTF 375 +LL SG+ +R+++ + Sbjct: 359 ELLSSGQGVRSIMIY 373 >3PII-A nrPDB Length = 339 Score = 310 bits (795), Expect = 5e-85, Method: Composition-based stats. Identities = 117/369 (31%), Positives = 163/369 (44%), Gaps = 38/369 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV--TPLPVILGH 68 KAAV+ + K+P I++VE EV +++ A G+C TD H G+ LP+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E GIVE VG GVT +K GD+V IP CG C C + + C Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEH------------- 108 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + + +++Y + V KI E+ I C T Y A+ V Sbjct: 109 --------QKNAGYSVDGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALKV 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A++G+GG G AV KA G ++AVDI +K AKELGA +NP Sbjct: 160 TGAKPGEWVAIYGIGGFGHVAVQYAKAMG-LNVVAVDIGDEKLELAKELGADLVVNP--L 216 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 K+ + +KE GGV + V S G V+VG+PP + I Sbjct: 217 KEDAAKFMKEKV-GGVHAAV-VTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDT 274 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G G++ G K + + A+ K I V P EKINE FD + G+ Sbjct: 275 -VLNGIKIIGSIVGTRKDLQEALQFAAEGKVK------TIIEVQPLEKINEVFDRMLKGQ 327 Query: 368 -SIRTVLTF 375 + R VLT Sbjct: 328 INGRVVLTL 336 >5TNX-A nrPDB Length = 383 Score = 303 bits (775), Expect = 1e-82, Method: Composition-based stats. Identities = 132/359 (36%), Positives = 184/359 (51%), Gaps = 10/359 (2%) Query: 19 KKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVG 78 PFSIE + P+ EV +++VA G+C TD V PLP +LGHE AG+VE+VG Sbjct: 27 GAPFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVG 86 Query: 79 EGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF-TCRGKP 137 V T+ GD V+ L CG C C YC + N G DG G+P Sbjct: 87 PNVKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEP 145 Query: 138 IH-HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTC 196 +H HF S+F+ Y + EN K+ +PLE + +GCG TG G+ +N V GS+ Sbjct: 146 LHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSF 205 Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 A FG G VG+SAVM + AGA IIAVDI + A A ELGAT IN ++ + + ++ Sbjct: 206 ASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIR 263 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP--PASQNLSINPMLLLTGRT 314 E+T GGVD++ E G + + GT +VG P +N LLL G T Sbjct: 264 EITGGGVDYALESTGLPAVLSQGIDALGSR-GTMGVVGAPKLGTKAEFDVN-SLLLGGHT 321 Query: 315 WKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVL 373 +G V G + IP+LV + +F D L+ P E+IN+ SG +++ +L Sbjct: 322 IRGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLV-KFYPLEQINQAAADSSSGITLKPIL 379 >1F8F-A nrPDB Length = 371 Score = 301 bits (770), Expect = 4e-82, Method: Composition-based stats. Identities = 125/366 (34%), Positives = 189/366 (51%), Gaps = 10/366 (2%) Query: 12 AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAA 71 AAV F ++ +++ P+ EV +K+VA G+C TD V PLP +LGHE + Sbjct: 9 AAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGS 68 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 131 GI+E++G VT ++ GD V+ L CGKC C YC + N G +G Sbjct: 69 GIIEAIGPNVTELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHAL 127 Query: 132 TCRGKPI--HHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 + + HF S+F+ Y + EN K+ P+E + +GCG TG G+ +N K Sbjct: 128 CTHDQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALK 187 Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 VTP S+ +G G VGLSA++ K GA+ IIAVDI + + AK+LGAT IN + + Sbjct: 188 VTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK-TQD 246 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP--PASQNLSINPM 307 P+ + KE+TDGGV+F+ E G + + + G +VG P + +N Sbjct: 247 PVAAI-KEITDGGVNFALESTGSPEILKQGVDALG-ILGKIAVVGAPQLGTTAQFDVND- 303 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 LLL G+T G V G K+ IP+LV + KF D L+ F++IN+ G Sbjct: 304 LLLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGI 362 Query: 368 SIRTVL 373 +++ ++ Sbjct: 363 TLKPII 368 >3MEQ-A nrPDB Length = 365 Score = 300 bits (767), Expect = 9e-82, Method: Composition-based stats. Identities = 105/371 (28%), Positives = 148/371 (39%), Gaps = 36/371 (9%) Query: 9 KCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVIL 66 KAAV+ KP +I++V + P ++++ + A G+C TD H G+ P I Sbjct: 25 TMKAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIP 84 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG GV VK GD+V IP CG CR C C + Sbjct: 85 GHEGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEE----------- 133 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + + F++Y V D N V + ++ + C T Y + Sbjct: 134 ----------QLNTGYSVNGGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGL 182 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 V PG + G+GG+G AV +A G + AVDI+ K A+ LGAT +N + Sbjct: 183 KVTDTKPGDWVVISGIGGLGHMAVQYARAMG-LNVAAVDIDDRKLDLARRLGATVTVNAK 241 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 P + KE TDGG V L GT + G+PP LSI Sbjct: 242 TVADPAAYIRKE-TDGGAQGVL-VTAVSPKAFEQALGMVARGGTVSLNGLPPGDFPLSIF 299 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 M +L G T +G++ G + AD K E IN FD + Sbjct: 300 NM-VLNGVTVRGSIVGTRLDLQESLDFAADGKVKA------TIQTGKLEDINAIFDDMRQ 352 Query: 366 GK-SIRTVLTF 375 G R V+ Sbjct: 353 GNIEGRIVMDL 363 >4Z6K-A nrPDB Length = 346 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 108/369 (29%), Positives = 161/369 (43%), Gaps = 38/369 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVILGH 68 KAAVL E + IE+V++ P A E+ +KM A G+C TD H V G+ P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E G++ +VGEGVT VK GD+V + CG C C C Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNS--------- 112 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +F++Y + + N V I + ++ + C T Y + + Sbjct: 113 ------------GYSVNGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKM 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G AV A G + AVDI+ DK A AK+LGA +N ++ Sbjct: 160 TDTKPGDWVVISGIGGLGHMAVQYAIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKN- 217 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 P + + KE+ GG + V L GT V G+PP +SI Sbjct: 218 TDPAEYLQKEI--GGAHGAL-VTAVSAKAFDQALSMLRRGGTLVCNGLPPGDFPVSIFDT 274 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G T +G++ G + + MA + A +T P E IN+ F+ + GK Sbjct: 275 -VLNGITIRGSIVGTRLDLQE-----SLDMAAAGKVKATVTAE-PLENINDIFERMRQGK 327 Query: 368 -SIRTVLTF 375 R V+ + Sbjct: 328 IEGRIVIDY 336 >1LLU-A nrPDB Length = 342 Score = 291 bits (744), Expect = 4e-79, Method: Composition-based stats. Identities = 100/371 (26%), Positives = 155/371 (41%), Gaps = 38/371 (10%) Query: 9 KCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV--TPLPVIL 66 KAAV+ P IE+V+V P +V +K+ A G+C TD H G+ PLP I Sbjct: 6 TMKAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIP 65 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG GVT VK GD+V IP CG C C C Sbjct: 66 GHEGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQ--------- 116 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + +++Y + D N V + ++ I C T Y + Sbjct: 117 ------------NTGYSVNGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGL 163 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 PG A+ G+GG+G AV +A G + A+DI+ K A++LGA+ +N + Sbjct: 164 KQTNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVNAR 222 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 + P++ + +++ GG V ++ + GT +VG+PP I Sbjct: 223 Q-EDPVEAIQRDI--GGAHGVL-VTAVSNSAFGQAIGMARRGGTIALVGLPPGDFPTPIF 278 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 ++L G G++ G + A A + + A I H + IN+ D + + Sbjct: 279 D-VVLKGLHIAGSIVGTRADLQE-----ALDFAGEGLVKATI-HPGKLDDINQILDQMRA 331 Query: 366 GK-SIRTVLTF 375 G+ R VL Sbjct: 332 GQIEGRIVLEM 342 >2DFV-A nrPDB Length = 347 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 97/360 (26%), Positives = 151/360 (41%), Gaps = 37/360 (10%) Query: 23 SIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL----VTPLPVILGHEAAGIVESVG 78 + +V+V P EV IK++A IC TD H+ N P I+GHE AG V +G Sbjct: 17 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIG 76 Query: 79 EGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPI 138 GV ++ GD V CGKC C+ + + C + G DG Sbjct: 77 PGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKI---FGVDTDGV---------- 123 Query: 139 HHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP--GSTC 196 F++Y VV + K + P E L G+AV+ P G + Sbjct: 124 --------FAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPISGKSV 170 Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 + G G +GL + KA+GA +I + + + AK++GA INP + + ++EV+ Sbjct: 171 LITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFE-EDVVKEVMD 229 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWK 316 GVD E G + L A G ++G+ P + N +++ T Sbjct: 230 ITDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTIDFNNLIIFKALTIY 288 Query: 317 GAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSGKSIRTVLTF 375 G G E + + K +LD +ITH F+K E F+L+ +GK+ + V Sbjct: 289 G--ITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFML 346 >3S2F-A nrPDB Length = 340 Score = 289 bits (739), Expect = 2e-78, Method: Composition-based stats. Identities = 102/369 (27%), Positives = 151/369 (40%), Gaps = 38/369 (10%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVILGH 68 KAAV+ P +I++V V P +V++K+ A G+C TD H G+ LP I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E G V +VG GV+ VK GD+V +P CG C C C K Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQ----------- 112 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + + +Y V D N V + ++ I C T Y + V Sbjct: 113 ----------NTGYSVNGGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKV 161 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G AV +A G R+ AVDI+ K A+ LGA +N +D Sbjct: 162 TDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARD- 219 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 P + KE+ GG V + + GT + G+PP I Sbjct: 220 TDPAAWLQKEI--GGAHGVL-VTAVSPKAFSQAIGMVRRGGTIALNGLPPGDFGTPIFD- 275 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 ++L G T +G++ G + + A + A ++ + +N+ F L GK Sbjct: 276 VVLKGITIRGSIVGTRSDLQE-----SLDFAAHGDVKATVS-TAKLDDVNDVFGRLREGK 329 Query: 368 -SIRTVLTF 375 R VL F Sbjct: 330 VEGRVVLDF 338 >3GFB-A nrPDB Length = 350 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 93/358 (25%), Positives = 148/358 (41%), Gaps = 37/358 (10%) Query: 23 SIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL----VTPLPVILGHEAAGIVESVG 78 + +V+V P EV IK++A IC TD H+ N P I+GHE AG V VG Sbjct: 18 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVG 77 Query: 79 EGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPI 138 GV ++ GD + CGKC CK+ + C + G DG Sbjct: 78 PGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKI---FGVDMDGV---------- 124 Query: 139 HHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP--GSTC 196 F+ Y +V K P E L G+AV+ P G + Sbjct: 125 --------FAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGRST 171 Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 + G G +GL + KA+GA +I + ++ + AK++GA +NP + + P++ V+ Sbjct: 172 LITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVKFVMD 230 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWK 316 GV+ E G + L G ++G+ P + N +++ Sbjct: 231 ITDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFPREVTIDFNNLIIFKALEVH 289 Query: 317 GAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSGKSIRTVL 373 G G E + + + K +LD +ITH F+K E F+L+ +GK+ + V Sbjct: 290 G--ITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >2EER-A nrPDB Length = 347 Score = 277 bits (709), Expect = 4e-75, Method: Composition-based stats. Identities = 104/376 (27%), Positives = 156/376 (41%), Gaps = 43/376 (11%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG---------NLVTP 61 +A L E+ KP +ED+ + PK +V IK+ A G+C +D H+ G +L Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ S +E + C T Sbjct: 119 GINYDG------------------AYAEYVLVPHYKYLYKLRRLSAVE-AAPLTCSGVTT 159 Query: 181 YGSAVNVAKVTPGSTCAVFGLGG-VGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y AV A + P T V G GG +G A+ KA A II VD+ ++ AK GA Sbjct: 160 YR-AVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 IN + P+ E+ + G D ++ T+ + G V+VG+ A Sbjct: 219 YVINAS-SQDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQ-GKYVMVGLFGAD 276 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 P++ L + G++ G GI L A+ + ++T + E+ NE Sbjct: 277 LKYHA-PLITLNEVQFIGSLVGNQSDFLGIMSL-----AEAGKVKPMVTKTMKLEEANEA 330 Query: 360 FDLLHSGKS-IRTVLT 374 D L + K+ R VL Sbjct: 331 IDNLENFKAVGRQVLV 346 >6N7L-A nrPDB Length = 353 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 103/370 (27%), Positives = 154/370 (41%), Gaps = 39/370 (10%) Query: 9 KCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV--TPLPVIL 66 KAAV+ +P I++V V P YEV +K++A G+C TD H V G+ +P+I Sbjct: 13 TMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIP 72 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE GIV + G VK GD V +P CG C C C G Sbjct: 73 GHEGVGIVVACGPDA-MVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNG------- 124 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + F++Y + D V + + ++ I C T Y + Sbjct: 125 --------------GYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGL 169 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + PG A+ G+GG+G AV KA G + A+D+ DK AK+LGA +N + Sbjct: 170 KETETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVNAK 228 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 P + KE+ GG+ + + + GT + G+PP S L I Sbjct: 229 -TTDPGTYLHKEV--GGMHGAL-ITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIF 284 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 +L T +G++ G K + A A + + A +T E IN+ FD + Sbjct: 285 ET-VLKRITVRGSIVGTRKDLQE-----ALDFANEGLVKATVTSA-KLEDINDVFDKMKK 337 Query: 366 GK-SIRTVLT 374 G+ R VL Sbjct: 338 GQIDGRIVLD 347 >1PL8-A nrPDB Length = 356 Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 88/360 (24%), Positives = 147/360 (40%), Gaps = 33/360 (9%) Query: 19 KKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIV 74 +E+ + P EV ++M +VGIC +D H GN + P++LGHEA+G V Sbjct: 16 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV 75 Query: 75 ESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCR 134 E VG V +KPGD+V CK N F C Sbjct: 76 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNL---------------SPSIFFCA 120 Query: 135 GKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194 P ++ + K+ E+ LI S G A VT G Sbjct: 121 TPP-----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGIH-ACRRGGVTLGH 173 Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-PQDYKKPIQE 253 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + ++ + I Sbjct: 174 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 233 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGR 313 ++ + + E G ++ A + + GT V+VG+ ++ P+L R Sbjct: 234 KVEGQLGCKPEVTIECTGAEASIQAGIYAT-RSGGTLVLVGL---GSEMTTVPLLHAAIR 289 Query: 314 TWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVL 373 + G F+ P ++ +K ++ L+TH P EK E F+ G ++ +L Sbjct: 290 EV--DIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 347 >2DQ4-A nrPDB Length = 343 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 92/368 (25%), Positives = 154/368 (41%), Gaps = 33/368 (8%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN----LVTPLPVIL 66 +A ++ ++ D V P E+ +++ A IC TD H+ + P++ Sbjct: 2 RALAKLAPEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVT 61 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 GHE +G+VE+VG GV + GD V C C C+ + CL + G +D Sbjct: 62 GHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQI---LGVDRD 118 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G F++Y VV P E V I F + Sbjct: 119 G------------------GFAEYVVVPAENAWVNPKDLPFE-VAAILEPFGNAVHTVYA 159 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 + V+ G + + G G +GL A M +A+GA I+ D N + A A+ A +NP Sbjct: 160 GSGVS-GKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP-- 215 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 ++ + EV++ +T GV+ E G + L+ G + I+G+P + Sbjct: 216 LEEDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIPSDPIRFDLAG 274 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 L++ G T G G + + + A + + L L+TH LP + E F LL SG Sbjct: 275 ELVMRGITAFG--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASG 332 Query: 367 KSIRTVLT 374 ++++ +L Sbjct: 333 QAVKVILD 340 >3QE3-A nrPDB Length = 355 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 89/360 (24%), Positives = 150/360 (41%), Gaps = 33/360 (9%) Query: 19 KKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIV 74 +E+ + P EV +KM +VGIC +D H G+ V P++LGHEA+G V Sbjct: 15 PGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTV 74 Query: 75 ESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCR 134 VG V ++PGD+V CK N F C Sbjct: 75 VKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTI---------------FFCA 119 Query: 135 GKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194 P ++ + N K+ E+ LI S G A A VT G+ Sbjct: 120 TPP-----DDGNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGIH-ACRRAGVTLGN 172 Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-PQDYKKPIQE 253 V G G +GL ++ KA GAA+++ D++ + +KAKE+GA + + + I + Sbjct: 173 KVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAK 232 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGR 313 ++ + + + E G ++ A + H GT V+VG+ ++ L+ Sbjct: 233 KVEGLLGSKPEVTIECTGVETSIQAGIYATHSG-GTLVLVGLGSEMTSVP-----LVHAA 286 Query: 314 TWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVL 373 T + + G F+ P ++ +K ++ L+TH P EK E F+ G ++ ++ Sbjct: 287 TREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMI 346 >4CPD-A nrPDB Length = 347 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 92/364 (25%), Positives = 160/364 (43%), Gaps = 24/364 (6%) Query: 13 AVLWEVKKPFSIEDVEVAPPK-AYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAA 71 AV++E K+ ++++V + + +++ GIC +D H+ G + +LGHE Sbjct: 3 AVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHEFV 62 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G VE+VGEG+ ++PGD V+ F CG C C+ + N C + + G Sbjct: 63 GQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVY--------GYGPM 114 Query: 132 TCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 191 + + FS + K+ E+ G ST YG + ++ Sbjct: 115 FGNLQGAQAEILRVPFSNV------NLRKLPPNLSPERAIFAGDILSTAYGGLIQ-GQLR 167 Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 PG + AV G G VGL A+ + GA++I+A+D ++ +A LGA IN + + P+ Sbjct: 168 PGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQ-ENPV 225 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLT 311 + V E D G D E +G T+ +L G VGV N P L + Sbjct: 226 RRVRSETNDEGPDLVLEAVGGAATLSLALEMV-RPGGRVSAVGV----DNAPSFPFPLAS 280 Query: 312 GRTWKGAVYGGFKSKE-GIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIR 370 G G + I ++A + + + +++H LP E+ G++L ++++ Sbjct: 281 GLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDRKEALK 340 Query: 371 TVLT 374 +L Sbjct: 341 VLLV 344 >5KIA-A nrPDB Length = 351 Score = 266 bits (681), Expect = 7e-72, Method: Composition-based stats. Identities = 90/370 (24%), Positives = 152/370 (41%), Gaps = 36/370 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN----LVTPLPVIL 66 KA E ++ V+ +V IK+ IC TD H+ + P+P+ + Sbjct: 10 KALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHV 69 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 GHE G + +G+ V GD+V CG CR C+ + C R T+ Sbjct: 70 GHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLC--------RNTVGV 121 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G R F++Y + KI + + I F +A++ Sbjct: 122 GVNRE-------------GAFAEYLAIPAFNAFKIPPEIS-DDLAAIFDPFGNATHTALS 167 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 V G + G G +G+ AV K GA ++ DIN + A+ +GAT +N Sbjct: 168 FNLV--GEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVS- 224 Query: 247 YKKPIQEVLKEM-TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 ++ +++V+ ++ G D E+ G + + SLL G ++G+PPA + N Sbjct: 225 -RESLRDVMADLHMTEGFDVGLEMSG-VPSAFTSLLESMNHGGKVALLGIPPAQTAIDWN 282 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 ++ G KG G + E K+VA + L +ITH + +GF + S Sbjct: 283 -QVIFKGLEIKGIY--GREMFETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFAAMLS 338 Query: 366 GKSIRTVLTF 375 G+S + +L + Sbjct: 339 GESGKVILDW 348 >4EEZ-A nrPDB Length = 348 Score = 257 bits (656), Expect = 7e-69, Method: Composition-based stats. Identities = 92/366 (25%), Positives = 147/366 (40%), Gaps = 33/366 (9%) Query: 12 AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAA 71 A V + + E+ K E + M G+C TD HV +G+ +LGHE Sbjct: 4 AVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHEGI 63 Query: 72 GIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRR 130 GIV+ +G V++++ GD+V + F CG C C + +C Sbjct: 64 GIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFC------------------ 105 Query: 131 FTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKV 190 R + ++ +V + K+ + I C T Y A+ V+ V Sbjct: 106 ---REVKNAGYSVDGGMAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTY-KAIKVSGV 161 Query: 191 TPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 PG +FG GG+G A+ K A++IAVDIN+DK AK++GA IN D P Sbjct: 162 KPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDV-NP 220 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 + E+ K GV + + + G V V VP LS+ P ++ Sbjct: 221 VDEIKKITGGLGVQSAIVC-AVARIAFEQAVASLKPMGKMVAVAVPNTEMTLSV-PTVVF 278 Query: 311 TGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK-SI 369 G G++ G + A+ + ++ E+IN+ D + +GK Sbjct: 279 DGVEVAGSLVGTRLDLAEAFQFGAE-----GKVKPIV-ATRKLEEINDIIDEMKAGKIEG 332 Query: 370 RTVLTF 375 R V+ F Sbjct: 333 RMVIDF 338 >1R37-A nrPDB Length = 347 Score = 253 bits (646), Expect = 9e-68, Method: Composition-based stats. Identities = 106/376 (28%), Positives = 160/376 (42%), Gaps = 43/376 (11%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG---------NLVTP 61 +A L E+ KP S++++ V PK +V IK+ A G+C +D H+ G +L Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ + +E + C T Sbjct: 119 GINFDG------------------AYAEYVIVPHYKYMYKLRRLNAVE-AAPLTCSGITT 159 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGL-SAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y AV A + P T V G GG AV KA A II VD+ ++ AK GA Sbjct: 160 YR-AVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 IN + P+ E+ + GVD ++ T+ + G V+VG+ A Sbjct: 219 YVINAS-MQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQ-GKYVMVGLFGAD 276 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 + P++ L+ + G++ G GI +L A+ + +IT + E+ NE Sbjct: 277 LHYHA-PLITLSEIQFVGSLVGNQSDFLGIMRL-----AEAGKVKPMITKTMKLEEANEA 330 Query: 360 FDLLHSGKSI-RTVLT 374 D L + K+I R VL Sbjct: 331 IDNLENFKAIGRQVLI 346 >5YLN-A nrPDB Length = 356 Score = 251 bits (641), Expect = 4e-67, Method: Composition-based stats. Identities = 98/368 (26%), Positives = 157/368 (42%), Gaps = 34/368 (9%) Query: 15 LWEVKKPFSIEDVEVAPP---KAYEVRIKMVAVGICRTDDHVVSGNLVT-PLPVILGHEA 70 + KP V+V P K + +++V IC TD H++ G++ T ILGHE Sbjct: 7 AYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEG 66 Query: 71 AGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRR 130 GIVE VGEGV+ K GDKV+ CGKC CK +C ++ G G L DG + Sbjct: 67 IGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCE-DEGGWIFGHLIDGMQ- 124 Query: 131 FTCRGKPIHHFLGTSTFSQYTVVD--ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 ++Y V +N + E + ++ TGY V Sbjct: 125 -----------------AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKG 167 Query: 189 KVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 KV PG + A+ G G VGL+A++ + A++I VD++ ++ A GAT +N D + Sbjct: 168 KVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPE 227 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML 308 K I+E+ GVD + E +G T GT GV ++ + Sbjct: 228 KAIKEIYDLTDGRGVDVAIEAVGIPATFDFC-QKIIGVDGTVANCGVHGKPVEFDLDKLW 286 Query: 309 LLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG-- 366 + V G S P+L+ + K + L+TH +I + +++ Sbjct: 287 I-----RNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAAD 341 Query: 367 -KSIRTVL 373 +I+ ++ Sbjct: 342 HHAIKVII 349 >5VM2-A nrPDB Length = 347 Score = 250 bits (638), Expect = 8e-67, Method: Composition-based stats. Identities = 92/353 (26%), Positives = 144/353 (40%), Gaps = 34/353 (9%) Query: 14 VLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDH-VVSGNLVTPL----PVILGH 68 + +V I E+ PK EV IK+ VGIC +D H SG + P + LGH Sbjct: 6 AILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGH 65 Query: 69 EAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT 128 E AG V +VG V KPGD+V CG CR C + N C D + + Sbjct: 66 ECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGAL 125 Query: 129 RRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 + C E+ K+ + L+ + G +A+ +A Sbjct: 126 THYLCH-------------------PESFTYKLPDNMDTMEGTLVEPA-AVGMHAAM-LA 164 Query: 189 KVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 V PG + G G +GL + CK GA I VD+ + + A A++LGAT IN + Sbjct: 165 DVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAK-E 223 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML 308 I + D G D FE G T+ + G +IVG P + +IN + Sbjct: 224 DTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRG-GKIMIVGTVPGAS--AINFLK 280 Query: 309 LLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 + T + F+ P + + +F + +++TH+ + + + F+ Sbjct: 281 INREVTIQTV----FRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >1H2B-A nrPDB Length = 359 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 94/378 (24%), Positives = 164/378 (43%), Gaps = 42/378 (11%) Query: 7 VIKCKAAVLWEVKKPFSIEDVEVAPP-KAYEVRIKMVAVGICRTDDHVVSGNL----VTP 61 V + KAA L E KP IEDV+ ++V +++ G+C TD H+V G Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 121 LP LGHE G +E V EGV ++ GD VI G C C+ E +C + Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEF---P 129 Query: 122 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKV---CLIGCGFS 178 G DG F+++ +V K+ EK+ + Sbjct: 130 GLNIDG------------------GFAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGI 171 Query: 179 TGYGSAVNVAK-VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 T Y + A+ + PG+ A+ G+GG+G AV K A +IA+D+ ++K A+ LG Sbjct: 172 TAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLG 231 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 A ++ + + P+++V++ GV+ + + +G T+ + G +IVG Sbjct: 232 ADHVVDAR--RDPVKQVMELTRGRGVNVAMDFVGSQATVDYTPYLLGR-MGRLIIVG-YG 287 Query: 298 ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKIN 357 ++ + +++G++ G + + +LV + K ++ I ++IN Sbjct: 288 GELRFPTI-RVISSEVSFEGSLVGNYV---ELHELVTLALQGKVRVEVDI---HKLDEIN 340 Query: 358 EGFDLLHSGKS-IRTVLT 374 + + L G+ R VL Sbjct: 341 DVLERLEKGEVLGRAVLI 358 >4OH1-A nrPDB Length = 351 Score = 247 bits (630), Expect = 7e-66, Method: Composition-based stats. Identities = 85/366 (23%), Positives = 142/366 (38%), Gaps = 45/366 (12%) Query: 20 KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-------TPLPVILGHEAAG 72 + + + PK E+RIK+V IC +D H+++GNL + LP+ GHE +G Sbjct: 19 GTVDMMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSG 78 Query: 73 IVESVGEGVT--TVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRR 130 +++ VG K G KV+ + CG C C+ + N C Sbjct: 79 VIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMG-------------- 124 Query: 131 FTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKV 190 + FS+Y V + + I + L+ L+ T S+ AK+ Sbjct: 125 -----------YRMNGFSEYAVYHMSQIFPIPDDADLKDYALVE--PLTVALSSAEQAKI 171 Query: 191 TPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 + G + A+ G GG+G+ V + AGA+ I DI +K A E GA +N + + Sbjct: 172 SYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EG 229 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 + E E+ G D E G L G +V + L +N L Sbjct: 230 VAERAIELAGGRYDCVLEGTGATAAAKLGLQLLAR-DGDAVYFAMYGKDPILPVN---LQ 285 Query: 311 TGRTW-KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSI 369 + W + ++G + PK + M + +I + F+ L+S K Sbjct: 286 SDLYWDQKHIHGMIQGAWQFPKSIR--MIPRMDFSKIIQKEHTLTNYKQAFEDLYSKKYA 343 Query: 370 RTVLTF 375 + V+ Sbjct: 344 KIVIKM 349 >5ENV-A nrPDB Length = 347 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 96/369 (26%), Positives = 145/369 (39%), Gaps = 36/369 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVILGH 68 K + +E +D+ V PKA E+ I + G+C TD H G+ P LP++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E AG+V +GE V K GD I C C C+ + C DL Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLS--------- 117 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +F QY D A I + L +V I C T Y A+ Sbjct: 118 ------------GYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKS 164 Query: 188 AKVTPGSTCAVFG-LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG+G AV KA G R++ +D + K + +G I+ Sbjct: 165 ANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTK 223 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 K + VLK TDGG V + AS A GT+V+VG+P ++ S Sbjct: 224 EKDIVGAVLKA-TDGGAHGVINVSVSEAAIEASTRYV-RANGTTVLVGMPAGAKCCSDVF 281 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 ++ + G+ G DF A+ + V+ + E ++ + G Sbjct: 282 NQVVKSISIVGSYVGNRADTRE----ALDFFARGLVKSPI--KVVGLSTLPEIYEKMEKG 335 Query: 367 K-SIRTVLT 374 + R V+ Sbjct: 336 QIVGRYVVD 344 >1YKF-A nrPDB Length = 352 Score = 243 bits (621), Expect = 7e-65, Method: Composition-based stats. Identities = 100/365 (27%), Positives = 159/365 (43%), Gaps = 35/365 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHE 69 K + + K + E P ++ ++ +AV C +D H V G + +ILGHE Sbjct: 2 KGFAMLSIGK-VGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHE 60 Query: 70 AAGIVESVGEGVTTVKPGDKVI-PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT 128 A G V VG V KPGD+V+ P TP V + + G + G Sbjct: 61 AVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW 110 Query: 129 RRFTCRGKPIHHFLGTSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 + + F ++ V++ +A + PLE +I +TG+ A Sbjct: 111 KFSNVKD---------GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-E 160 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 +A + G+T AV G+G VGL AV G K GA RIIAV AK GAT+ +N +D Sbjct: 161 LADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD 220 Query: 247 YKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 PI+ + +T+G GVD + G D +MA+ + + GT V + L + Sbjct: 221 --GPIESQIMNLTEGKGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVP 277 Query: 306 PMLL---LTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFD 361 + + +T KG + G + + + +L+ K+ L+THV F+ I + F Sbjct: 278 RLEWGCGMAHKTIKGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFM 335 Query: 362 LLHSG 366 L+ Sbjct: 336 LMKDK 340 >1E3J-A nrPDB Length = 352 Score = 241 bits (615), Expect = 4e-64, Method: Composition-based stats. Identities = 80/372 (21%), Positives = 148/372 (39%), Gaps = 39/372 (10%) Query: 12 AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS----GNLVTPLPVILG 67 +AVL++ +E + PK EV ++M VGIC +D H + + P+++G Sbjct: 7 SAVLYKQND-LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 HEA+G V VG+ V +K GD+V C +C+ CK + N C Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTF---------- 115 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 C P ++Y V + K+ LE+ L+ S G A Sbjct: 116 -----CATPP-----DDGNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGVH-ACRR 163 Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN---P 244 A V G+T V G G +GL +V+ KA GA ++ + + AK GA + Sbjct: 164 AGVQLGTTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPA 222 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304 ++ + I E ++ + + + G + + GT ++VG+ + Sbjct: 223 KEEESSIIERIRSAIGDLPNVTIDCSGNEKCITIGIN-ITRTGGTLMLVGMGSQMVTVP- 280 Query: 305 NPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD--L 362 L+ + + F+ P + + + ++ L+TH E+ + F+ Sbjct: 281 ----LVNACAREIDIKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFEAAR 336 Query: 363 LHSGKSIRTVLT 374 + +I+ +++ Sbjct: 337 KKADNTIKVMIS 348 >4EJ6-A nrPDB Length = 370 Score = 240 bits (612), Expect = 8e-64, Method: Composition-based stats. Identities = 91/364 (25%), Positives = 148/364 (40%), Gaps = 30/364 (8%) Query: 13 AVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAG 72 AV E S+ +V + P ++ +K+ A GIC TD H++ G + PV LGHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 IV G V + PG ++ CG+C C+ N C G +DG Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLR---AIGIHRDG----- 137 Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 F++Y +V +I L+ V C V+++ + Sbjct: 138 -------------GFAEYVLVPRKQAFEIP--LTLDPVHGAFCEPLACCLHGVDLSGIKA 182 Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKP 250 GST A+ G G +GL V + AGA +I K A+E+GAT ++P D + Sbjct: 183 GSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEA 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 I + + GGVD E G +T+ S +A GT VI+GV P + + I P +L Sbjct: 243 IAGPVG-LVPGGVDVVIECAGVAETVKQSTR-LAKAGGTVVILGVLPQGEKVEIEPFDIL 300 Query: 311 TGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIR 370 V G F + + +D +I+ + ++ + + ++ Sbjct: 301 FRELR---VLGSFINPFVHRRAADLVATGAIEIDRMISRRISLDEAPDVISNPAAAGEVK 357 Query: 371 TVLT 374 ++ Sbjct: 358 VLVI 361 >1UUF-A nrPDB Length = 369 Score = 239 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 88/362 (24%), Positives = 142/362 (39%), Gaps = 31/362 (8%) Query: 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVIL 66 +K KA + K+P D+ P +V+I++ G+C +D H V T P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE G V +VG+ V PGD V + C C C++ NYC Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCD----------HM 130 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKI-DAASPLEKVCLIGCGFSTGYGSA 184 GT +P H +SQ VV E V +I L V + C T Y Sbjct: 131 TGTYNSPTPDEPGHTL---GGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPL 187 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 + + PG V G+GG+G + A GA ++A ++ K AK LGA E +N Sbjct: 188 RH-WQAGPGKKVGVVGIGGLGHMGIKLAHAMGA-HVVAFTTSEAKREAAKALGADEVVNS 245 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304 ++ + + DF + + + GT +VG P Sbjct: 246 RNADEMAAHL------KSFDFILNTVAAPHNL-DDFTTLLKRDGTMTLVGAPATPHKSPE 298 Query: 305 NPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLH 364 L++ R G++ GG + + DF A+ + + ++ ++INE ++ + Sbjct: 299 VFNLIMKRRAIAGSMIGGIPETQEML----DFCAEHGIVADI--EMIRADQINEAYERML 352 Query: 365 SG 366 G Sbjct: 353 RG 354 >5H82-A nrPDB Length = 389 Score = 238 bits (608), Expect = 3e-63, Method: Composition-based stats. Identities = 77/336 (22%), Positives = 128/336 (38%), Gaps = 17/336 (5%) Query: 33 KAYEVRIKMVAVGICRTDDHVVSGNLVT-PLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 ++V+ K++ G+C D T P + GHE GIV +G V K GDKV Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVG 111 Query: 91 IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQY 150 + F CGKC C YC K + D +S Sbjct: 112 VGNFIGSCGKCERCNEGLEPYCPKV-IYTDGTAFSDENNTVYGDVSGDGEDRIYGGYSNI 170 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVM 210 V +E V + PL I CG Y + PG + V G G +G AV Sbjct: 171 MVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLAVK 230 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 KA GA + K ++ G + ++ ++ + + +D F+ + Sbjct: 231 FAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEE------MKAAESTLDGIFDCV 284 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIP 330 + + L + GT V++GV + L ++P LL+ R + G++ G K + + Sbjct: 285 PSVHPLHPL-LNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMKETQEML 342 Query: 331 KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 DF AK + + ++P + +N + + G Sbjct: 343 ----DFAAKHNIVSDI--ELIPMDYVNTALERIAKG 372 >3FSR-A nrPDB Length = 352 Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats. Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 33/364 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHE 69 K + + K + E P ++ ++ +AV C +D H V G + +ILGHE Sbjct: 2 KGFAMLSIGK-VGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHE 60 Query: 70 AAGIVESVGEGVTTVKPGDKVI-PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT 128 A G V VG V KPGD+V+ P TP V + + G + G Sbjct: 61 AVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW 110 Query: 129 RRFTCRGKPIHHFLGTSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 + + F ++ V++ +A + PLE +I +TG+ A Sbjct: 111 KFSNVKD---------GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-E 160 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 +A + GS+ V G+G VGL + G K GA RII V AK GAT+ +N ++ Sbjct: 161 LADIQMGSSVVVIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN 220 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 + +V+K GVD G +T+ ++ + G + + L I Sbjct: 221 -GHIVDQVMKLTNGKGVDRVIMAGGGSETLSQAV-SMVKPGGIISNINYHGSGDALLIPR 278 Query: 307 MLL---LTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDL 362 + + +T KG + G + + + +L+ K+ L+THV F+ I + F L Sbjct: 279 VEWGCGMAHKTIKGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFML 336 Query: 363 LHSG 366 + Sbjct: 337 MKDK 340 >3FPC-A nrPDB Length = 352 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 90/364 (24%), Positives = 146/364 (40%), Gaps = 33/364 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHE 69 K + + K + E P ++ ++ +AV C +D H V G + +ILGHE Sbjct: 2 KGFAMLSIGK-VGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHE 60 Query: 70 AAGIVESVGEGVTTVKPGDKVI-PLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT 128 A G V VG V KPGD+V+ P TP V + + G + G Sbjct: 61 AVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW 110 Query: 129 RRFTCRGKPIHHFLGTSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 + + F ++ V++ +A + PLE +I +TG+ A Sbjct: 111 KFSNVKD---------GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-E 160 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 +A + G T V G+G VGL +V G GA RI AV K A E GAT+ IN ++ Sbjct: 161 LANIKLGDTVCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN 220 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 ++++LK GVD G + T ++ + V N+ I Sbjct: 221 -GDIVEQILKATDGKGVDKVVIAGGDVHTFAQAVKMI-KPGSDIGNVNYLGEGDNIDIPR 278 Query: 307 MLL---LTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDL 362 + + G + G + + + +L+ K+ L+THV F+ I + F L Sbjct: 279 SEWGVGMGHKHIHGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFML 336 Query: 363 LHSG 366 + Sbjct: 337 MKDK 340 >3FPL-A nrPDB Length = 351 Score = 233 bits (595), Expect = 7e-62, Method: Composition-based stats. Identities = 98/353 (27%), Positives = 150/353 (42%), Gaps = 32/353 (9%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEG 80 + E +Y+ ++ +AV C +D H V G L +ILGHEA G V VG Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 81 VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHH 140 V KPGD+VI T + + + G +DG Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGV------------ 119 Query: 141 FLGTSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAV 198 F +Y V++ +A + PLE +I +TG+ A +A + G+T AV Sbjct: 120 ------FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAV 172 Query: 199 FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G+G VGL AV G K GA RIIAV AK GAT+ +N +D PI+ + + Sbjct: 173 LGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNL 230 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL---LTGRT 314 T+G GVD + G D +MA+ + + GT V + L + + + +T Sbjct: 231 TEGKGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKT 289 Query: 315 WKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSG 366 KG + G + + + + + + L L+THV F+ I E L+ Sbjct: 290 IKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 >3TWO-A nrPDB Length = 348 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 96/374 (25%), Positives = 148/374 (39%), Gaps = 39/374 (10%) Query: 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP-LPVIL 66 ++ K ++ + F D +V I ++ GIC +D H P+I Sbjct: 3 VQSKGFAIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIP 62 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE AGI++ VG+GV K GD V + F C C+ CK + +C K Sbjct: 63 GHEIAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKV---------- 112 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + C + +S VVDEN V +D +PLEKV + C T Y + Sbjct: 113 --VFTYDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTYSP-L 169 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NP 244 +KVT G+ V G GG+G AV A GA + N+ K A +G +P Sbjct: 170 KFSKVTKGTKVGVAGFGGLGSMAVKYAVAMGA-EVSVFARNEHKKQDALSMGVKHFYTDP 228 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--ASQNL 302 + K+ + DF I + L G +VG+PP + L Sbjct: 229 KQCKEEL------------DFIISTIPTHYDLKDYLK-LLTYNGDLALVGLPPVEVAPVL 275 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 S+ + L R G++ GG K + + K ++ I +L + I+ + Sbjct: 276 SVFDFIHLGNRKVYGSLIGGIKETQEMVDFSI-----KHNIYPEIDLILG-KDIDTAYHN 329 Query: 363 LHSGKS-IRTVLTF 375 L GK+ R V+ Sbjct: 330 LTHGKAKFRYVIDM 343 >4GKV-A nrPDB Length = 336 Score = 230 bits (586), Expect = 8e-61, Method: Composition-based stats. Identities = 101/367 (27%), Positives = 153/367 (41%), Gaps = 36/367 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEA 70 KAAV+ + + + K E +KM G+C TD HV +G+ VILGHE Sbjct: 2 KAAVVTKDH-HVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEG 60 Query: 71 AGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTR 129 G+V VG GVT++KPGD+ + F CG C C + C Sbjct: 61 IGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLC----------------- 103 Query: 130 RFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 R + ++ +V + K+ I C T Y AV ++K Sbjct: 104 ----RSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTY-KAVKLSK 158 Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 + PG A++GLGG+G A+ K A++IA+D+N ++ A E+GA IN + + Sbjct: 159 IRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTE 216 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL 309 ++++E T G V S + A G V VG+PP S +L I P L+ Sbjct: 217 DAAKIVQEKTGGAHAAV--VTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLV 273 Query: 310 LTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK-S 368 L G G++ G + + A+ K + P IN F + GK Sbjct: 274 LDGIEVVGSLVGTRQDLTEAFQFAAE---GKVVPK---VALRPLADINTIFTEMEEGKIR 327 Query: 369 IRTVLTF 375 R V+ F Sbjct: 328 GRMVIDF 334 >5YAT-A nrPDB Length = 350 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 94/369 (25%), Positives = 144/369 (39%), Gaps = 36/369 (9%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV--TPLPVILGH 68 KA + P +D+ V PK+ E+ I + G+C TD H G+ LP++ GH Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGH 69 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 E AG+V + GE VT + GD I C C C + C K DL Sbjct: 70 EGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLS--------- 120 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 F +F QY D A+I + L +V I C T Y A+ Sbjct: 121 ------------GFTHDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALKT 167 Query: 188 AKVTPGSTCAV-FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ GG+G AV KA G R++ +D DK K LGA ++ Sbjct: 168 ADLRIGQWVAISGAGGGLGSLAVQYAKALG-LRVLGIDGGADKGEFVKSLGAEVFVDFTK 226 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 K + EV K +T+GG V + S+ G V+VG+P + S Sbjct: 227 TKDVVAEVQK-LTNGGPHGVINVSVSPHAINQSVQYV-RTLGKVVLVGLPSGAVVNSDVF 284 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +L KG+ G + D + + ++ ++ + ++ + +G Sbjct: 285 WHVLKSIEIKGSYVGNREDSAE----AIDLFTRGLVKAPI--KIIGLSELAKVYEQMEAG 338 Query: 367 KSI-RTVLT 374 I R V+ Sbjct: 339 AIIGRYVVD 347 >1KEV-A nrPDB Length = 351 Score = 226 bits (577), Expect = 9e-60, Method: Composition-based stats. Identities = 90/353 (25%), Positives = 143/353 (40%), Gaps = 32/353 (9%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV-SGNLVTPLPVILGHEAAGIVESVGEG 80 + E +Y+ ++ +AV C +D H V G L +ILGHEA G V VG Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 81 VTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIH 139 V KPGD+V +P TP V + + G +DG Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEV-QAGFQQHSNGMLAGWKFSNFKDGV----------- 119 Query: 140 HFLGTSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 F +Y V++ +A + PLE +I +TG+ A +A + GS+ Sbjct: 120 -------FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVV 171 Query: 198 VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 257 V G+G VGL + G K GA RII V AK GAT+ +N ++ + +V+K Sbjct: 172 VIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKL 230 Query: 258 MTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL---LTGRT 314 GVD G +T+ ++ + G + + L I + + +T Sbjct: 231 TNGKGVDRVIMAGGGSETLSQAV-SMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHKT 289 Query: 315 WKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSG 366 KG + G + + + + + + L L+THV F+ I E L+ Sbjct: 290 IKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 >3M6I-A nrPDB Length = 363 Score = 226 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 77/364 (21%), Positives = 143/364 (39%), Gaps = 39/364 (10%) Query: 15 LWEVKKPFSIEDVEVAP-PKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPV----ILGHE 69 LW + S+E V+ K EV + + + GIC +D H + P+ V +LGHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTR 129 +AG V +V V ++K GD+V C C C N C + D + R Sbjct: 80 SAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPV-PGLLR 138 Query: 130 RFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 R+ H +G ++ +++ +VA + + A Sbjct: 139 RYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQRAG 176 Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 V G + G G +GL ++ KAAGA ++ DI++ + AKE+ E + + + Sbjct: 177 VRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEI-CPEVVTHKVERL 235 Query: 250 PIQEVLKEMTD--GGVD--FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 +E K++ + GG++ + E G ++ A+ + + G ++GV + Sbjct: 236 SAEESAKKIVESFGGIEPAVALECTGVESSI-AAAIWAVKFGGKVFVIGVGKNEIQIP-- 292 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 + + + ++ P+ + L L+TH P E + F+ Sbjct: 293 ---FMRASVREVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFETASD 349 Query: 366 GKSI 369 K+ Sbjct: 350 PKTG 353 >5K1S-A nrPDB Length = 362 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 93/369 (25%), Positives = 146/369 (39%), Gaps = 34/369 (9%) Query: 11 KAAVLWEVK--KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TPLPVILG 67 KA VL +E + + P EV +++ A G+C D GNL T +P ILG Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 HEAAG V VG K GD+ L CG C +C++ ++ C ++ Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDN----------- 127 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 RF P ++Q+ V + ++ A+ P + + C T + Sbjct: 128 --RFFGEELP-------GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTR 178 Query: 188 AKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 KV G T + G GGVGLS+V + GA R+IAV ++ K KE GA E I + Sbjct: 179 GKVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSRG 237 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 +V K GVD + E++G L G V+VG + Sbjct: 238 L-DFASDVRKRTQGAGVDVAVEIVGSA--TFDQTLKSMAPGGRVVVVGNLESGMVQLNPG 294 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 ++++ GA + +L A + +T +P + + L + Sbjct: 295 LVIVKELEILGAYATTQAELDEALRLTA-----TGGVRQFVTDAVPLAEAAKAHFRLENR 349 Query: 367 K-SIRTVLT 374 + + R VL Sbjct: 350 EVAGRLVLV 358 >4ILK-A nrPDB Length = 359 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 93/372 (25%), Positives = 146/372 (39%), Gaps = 46/372 (12%) Query: 13 AVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG-NLVTPLPVILGHEAA 71 ++L E SI + E+ P A EVR+K+ GIC +D H+ G N P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G++++VGEGV + + G++V CG C C + N C + G DG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADG---- 135 Query: 132 TCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 191 FS+Y VV KI A + +I T + + T Sbjct: 136 --------------GFSEYAVVPAKNAWKIPEAVADQYAVMIE--PFTIAANVTGHGQPT 179 Query: 192 PGSTCAVFGLGGVGLSAVMGCK-AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 T V+G G +GL+ V K +I D ++ KAKE GA IN + + P Sbjct: 180 ENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--NSQTP 237 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS---QNLSINPM 307 + E SF G T++ C +V + P A S P Sbjct: 238 LGE------------SFAEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPS 285 Query: 308 LLL-TGRT-WKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL--L 363 ++ G T + +++ + P ++ + LITH F+ + + L L Sbjct: 286 EVIQQGITGKELSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEL 345 Query: 364 HSGKSIRTVLTF 375 + +LTF Sbjct: 346 DQKHCCKVLLTF 357 >4OAQ-A nrPDB Length = 367 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 83/367 (22%), Positives = 148/367 (40%), Gaps = 34/367 (9%) Query: 16 WEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL--VTPLPVILGHEAAGI 73 W K S E ++ P ++V +K G+C +D H +S + +++GHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 74 VESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 V +VG+ VT K GD+V I + C C+ C + YC + G + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ------------GAATYN 124 Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV-NVAKVT 191 + ++++ +S +++ DE V I P + C T + + N+ Sbjct: 125 SKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDA 184 Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G + G+GG+G A+ A GA + A + K +A +LGA + + + K Sbjct: 185 RGKNVGIIGIGGLGHLALQFANAMGA-NVTAFSRSSSKKEQAMKLGAHDFVATGEDKTWY 243 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMAS-LLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 + D DF +D + S L + V VG+PP+ ++P L Sbjct: 244 KNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTFL 298 Query: 311 -TGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHV-LPFEKINEGFDLLHSGKS 368 G ++ ++ G + + L A K ++ +I V + E + D H+G Sbjct: 299 QQGASFGSSLLGSKTEVKEMLNL-----AAKHNVRPMIEEVPISEENCAKALDRCHAG-D 352 Query: 369 IRTVLTF 375 +R F Sbjct: 353 VRYRFVF 359 >1YQX-A nrPDB Length = 366 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 78/348 (22%), Positives = 128/348 (36%), Gaps = 30/348 (8%) Query: 20 KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TPLPVILGHEAAGIVESVG 78 S + +VR K++ G+C +D H + + + P++ GHE G V VG Sbjct: 27 GHLSPFNFSRRATGEEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVG 86 Query: 79 EGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137 V V GDKV + C C C N NYC K + DGT + Sbjct: 87 SKVKKVNVGDKVGVGCLVGACHSCESCANDLENYCPKM-ILTYASIYHDGTITY------ 139 Query: 138 IHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 +S + V +E + + PL+ + C T Y PG Sbjct: 140 -------GGYSNHMVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIG 192 Query: 198 VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 257 + GLGG+G AV KA G+ + K K GA + +D ++ + Sbjct: 193 IVGLGGLGHVAVKFAKAFGSKVTVISTSPSKKEEALKNFGADSFLVSRDQEQ------MQ 246 Query: 258 MTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKG 317 G +D + + + ++ L ++ G ++VG P L L+ + G Sbjct: 247 AAAGTLDGIIDTVSAVHPLL-PLFGLLKSHGKLILVGAPEKPLELPAF-SLIAGRKIVAG 304 Query: 318 AVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 + GG K + + DF AK + V+ + +N + L Sbjct: 305 SGIGGMKETQEM----IDFAAKHNITADI--EVISTDYLNTAMERLAK 346 >2H6E-A nrPDB Length = 344 Score = 223 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 98/378 (25%), Positives = 161/378 (42%), Gaps = 45/378 (11%) Query: 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSG---NLVTPLP 63 ++K KAA+L + +P SIEDV + P+ EV I++ G+CRTD V G LP Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGT 123 +ILGHE AG + VGE + VK GD V+ T CR C+ + N C Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC----------- 108 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVV-DENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + + I FS+Y +V + K+++ SP+E + +T G Sbjct: 109 ----------KNQIIPGQTTNGGFSEYMLVKSSRWLVKLNSLSPVE-AAPLADAGTTSMG 157 Query: 183 S---AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKA-AGAARIIAVDINKDKFAKAKELGA 238 + A+ V G+GG+ + + KA I+ + +K A ELGA Sbjct: 158 AIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFALELGA 217 Query: 239 TECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 +D + ++ ++TDG G + +++G +T L G ++VG+ Sbjct: 218 DYVSEMKD----AESLINKLTDGLGASIAIDLVGTEETTYN-LGKLLAQEGAIILVGMEG 272 Query: 298 ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKIN 357 +L + + G+ YG E + +L ++ + I V P + IN Sbjct: 273 KRVSLEAFDTAVWN-KKLLGSNYGSLNDLEDVVRL-----SESGKIKPYIIKV-PLDDIN 325 Query: 358 EGFDLLHSGK-SIRTVLT 374 + F L G+ R V+T Sbjct: 326 KAFTNLDEGRVDGRQVIT 343 >5Z0C-A nrPDB Length = 374 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 92/366 (25%), Positives = 130/366 (35%), Gaps = 30/366 (8%) Query: 2 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 61 T +K + S +V K++ GIC +D H + Sbjct: 6 GTEEHTVKAVGWAARDPSGHLSPFTFSRRATGELDVTFKVLYCGICHSDLHYIKNEWSNT 65 Query: 62 -LPVILGHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGN 119 P + GHE G V VG V K GDKV + C C C N NYC N + Sbjct: 66 IYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGCIVGSCHSCPNCNNHLENYC-PNRILT 124 Query: 120 PRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 DGT L +S VV E+ +I A PL+ + C T Sbjct: 125 FGSRYYDGT-------------LNHGGYSDLMVVQEHFAVRIPDALPLDSAAPLLCAGIT 171 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y PG V GLGG+G AV KA G + K LGA Sbjct: 172 VYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKAFGVKVTVVSTSPAKKEDAISGLGAH 231 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 I D ++ V G +D + + + L+ ++ G V+VG PP Sbjct: 232 SFILSTDAEQMQAAV------GTMDGIIDTV-SASHPLPPLISLLKSHGKLVMVGDPPKP 284 Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 L + P LLL + G+ GG K + + DF AK+ + V+P + +N Sbjct: 285 LELPVFP-LLLGRKMVAGSAIGGMKETQEM----IDFAAKEGVRADV--EVIPMDYVNTA 337 Query: 360 FDLLHS 365 + Sbjct: 338 MQRVSK 343 >6DKH-A nrPDB Length = 346 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 79/343 (23%), Positives = 128/343 (37%), Gaps = 35/343 (10%) Query: 38 RIKMVAVGICRTDDHVVS----GNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL 93 +++ GIC +D H GN + P++LGHE G V + + + G V Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAIN 91 Query: 94 FTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV 153 + CG C+ C N C RF H F++Y +V Sbjct: 92 PSKPCGHCKYCIEHNENQCTD--------------MRFFGSAMYFPHV--DGGFTRYKMV 135 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCK 213 + + A + EKV + +A ++ G + G+G +G V K Sbjct: 136 ETSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVK 193 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 GAA I+ D++ + KE+GA +NPQ+ + K G D SFEV G Sbjct: 194 TLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEK----GYFDVSFEVSGHP 249 Query: 274 DTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLV 333 ++ L A G V VG+ A PM+ L G+ ++ G F+ V Sbjct: 250 SSVNTCLEVT-RARGVMVQVGMGGAMAE---FPMMTLIGKEI--SLRGSFRFTSEFNTAV 303 Query: 334 ADFMAKKFSLDALITHVLPFEKINEGFDLL-HSGKSIRTVLTF 375 + + L++ PF + E ++ + L F Sbjct: 304 SWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >4UEJ-A nrPDB Length = 346 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 86/369 (23%), Positives = 143/369 (38%), Gaps = 33/369 (8%) Query: 13 AVLWEVKKPFSIEDVEVAPPKA-YEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAA 71 +V+ + + + + K EVR+K+ + G+C +D + N P+ LGHE + Sbjct: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 Query: 72 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 131 G +++VG GV + PGD V + C C C + C K D G+ +DG Sbjct: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDG---- 115 Query: 132 TCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 191 F++Y VV V + P+E I T A ++A+ Sbjct: 116 --------------GFAEYIVVKRKNVFALPTDMPIEDGAFIE--PITVGLHAFHLAQGC 159 Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP- 250 + G G +GL A+ A GA + A+DI+ +K A AK GA + N + P Sbjct: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLS--INPML 308 +Q VL+E+ E G T+ ++ +VG +L+ + Sbjct: 220 MQSVLRELRFN--QLILETAGVPQTVELAVEIAGPHA-QLALVGTLHQDLHLTSATFGKI 276 Query: 309 LLTGRTWKGAVYGGFKSK--EGIPKLVADFMAKKFSLDALITHVLPFEKINEGF-DLLHS 365 L T G+ + +K SL+ LI H FE + D+ + Sbjct: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 Query: 366 GKSIRTVLT 374 + +L Sbjct: 337 AMPGKVLLI 345 >3IP1-A nrPDB Length = 404 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 81/378 (21%), Positives = 137/378 (36%), Gaps = 47/378 (12%) Query: 15 LWEVKKPFSIEDVEVAPP-KAYEVRIKMVAVGICRTDDHVVSGN--------LVTPLPVI 65 +W + +E+V K E+ IK+ A GIC +D H+ + +T PV Sbjct: 36 VWRYPE-VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVT 94 Query: 66 LGHEAAGIVESVGEGV------TTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGN 119 LGHE +G+V G + G+ V CG CR C N+C + Sbjct: 95 LGHEFSGVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLN--- 151 Query: 120 PRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEK------VCLI 173 F F++Y VD + + + + Sbjct: 152 ------------------ELGFNVDGAFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSL 193 Query: 174 GCGFSTGYGSA-VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAK 232 S Y + V + PG + G G +GL+AV K AGA+++I + ++ + Sbjct: 194 VEPTSVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNL 253 Query: 233 AKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL-LCCHEACGTSV 291 AKELGA I+P + ++ VL G E G + + A G + Sbjct: 254 AKELGADHVIDPTK-ENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINA 312 Query: 292 IVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVL 351 V + + + R + G P++++ MA + +I+ + Sbjct: 313 TVAIVARADAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTV 371 Query: 352 PFEKINEGFDLLHSGKSI 369 E+I E L + KS+ Sbjct: 372 SMEEIPEYIKRLQTDKSL 389 >6FG0-A nrPDB Length = 352 Score = 210 bits (534), Expect = 9e-55, Method: Composition-based stats. Identities = 83/361 (22%), Positives = 138/361 (38%), Gaps = 32/361 (8%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS---GNLVTPLPVILG 67 KA E+ + D+ P E+ +K+ A G+C +D V+ LP+ LG Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 HE G V +GEGVT GD V CG C C NYC Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYC--------------- 106 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN- 186 R G + + ++Y +VD + T Y + Sbjct: 107 -TRAADLGITPPGYGSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAISRV 165 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 + + PGST V G+GG+G + +A AAR+IAVD++ D+ A A+E+GA + Sbjct: 166 LPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKS-- 223 Query: 247 YKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 + ++E+T G G F+ +G T+ + G +VG+ + + Sbjct: 224 -GAGAADAIRELTGGQGATAVFDFVGAQSTI-DTAQQVVAVDGHISVVGIHAGAHA-KVG 280 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 ++ G + +G + ++VA A + + T ++ + L Sbjct: 281 FWMIPFGASVVTPYWGTRS---ELMEVVALARAGRLDIH---TETFTLDEGPAAYRRLRE 334 Query: 366 G 366 G Sbjct: 335 G 335 >5FI5-A nrPDB Length = 357 Score = 208 bits (530), Expect = 3e-54, Method: Composition-based stats. Identities = 79/360 (21%), Positives = 133/360 (36%), Gaps = 38/360 (10%) Query: 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TPLPVIL 66 +K + FS + ++V++K++ G C+ D + T P +L Sbjct: 16 VKAFGLAAKDSSGLFSPFNFSRRATGEHDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVL 75 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE G V VG V K GDKV + CGKC +C N NYC + + Sbjct: 76 GHEIVGEVTEVGSKVQKFKVGDKVGVASIIETCGKCEMCTNEVENYCPEAGSIDS----- 130 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 S V++EN V + PL+ + C T Y Sbjct: 131 -----------------NYGACSNIAVINENFVIRWPENLPLDSGVPLLCAGITAYSPMK 173 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 PG + GLGG+G A+ KA GA + K K ++ GA + Sbjct: 174 RYGLDKPGKRIGIAGLGGLGHVALRFAKAFGAKVTVISSSLKKKREAFEKFGADSFLVSS 233 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSIN 305 + ++ + G +D + I ++ LL + G +I+G P + Sbjct: 234 NPEE------MQGAAGTLDGIIDTIPGNHSLE-PLLALLKPLGKLIILGAPEMPFEVPA- 285 Query: 306 PMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 P LL+ G+ + G K + + +F A+ + + V+ + +N + L + Sbjct: 286 PSLLMGGKVMAASTAGSMKEIQEM----IEFAAEHNIVADV--EVISIDYVNTAMERLDN 339 >2OUI-A nrPDB Length = 360 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 83/355 (23%), Positives = 139/355 (39%), Gaps = 32/355 (9%) Query: 20 KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDH-VVSGNLVTPLPVILGHEAAGIVESVG 78 + ++ + ++ +A+ C +D H V +G + +ILGHEA G + VG Sbjct: 10 GRIGWIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVG 69 Query: 79 EGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137 V +K GDKV +P TP G+ + + G + G + + Sbjct: 70 SLVKRLKVGDKVIVPAITPDWGEEESQRGYPMH----------SGGMLGGWKFSNFKD-- 117 Query: 138 IHHFLGTSTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195 FS+ V+E +A + E ++ +TG+ A +A + G T Sbjct: 118 -------GVFSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDT 169 Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 V G+G VGL +V G GA RI AV K A E GAT+ IN ++ ++++L Sbjct: 170 VCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN-GDIVEQIL 228 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL---LTG 312 K GVD G + T ++ + V N+ I + Sbjct: 229 KATDGKGVDKVVIAGGDVHTFAQAVKMI-KPGSDIGNVNYLGEGDNIPIPRSEWGVGMGH 287 Query: 313 RTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSG 366 + G + G + + + KL + K LITH EK+ + L+ + Sbjct: 288 KHIHGGLTPGGRVR--MEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNK 340 >1YB5-A nrPDB Length = 351 Score = 203 bits (517), Expect = 9e-53, Method: Composition-based stats. Identities = 78/385 (20%), Positives = 147/385 (38%), Gaps = 66/385 (17%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSIE---DVEVAPPKAYEVRIKMVAVGICRTDDHVVSGN 57 M+T K+++ A ++E P ++ D+ V PK ++V IK+ A G+ + ++ SG Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 LVTP--LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKN 115 LP G + AG++E+VG Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVG------------------------------------- 103 Query: 116 DLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 D F + + +++Y + ++ V K+ ++ IG Sbjct: 104 ----------DNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGAAIGI 153 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK 234 + T Y + ++ A V G + V G GGVGL+A +A G +I+ ++ Sbjct: 154 PYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVL 212 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + GA E N ++ I ++ K + + G+D E++ ++ L G ++VG Sbjct: 213 QNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKD--LSLLSHGGRVIVVG 269 Query: 295 VPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAK--KFSLDALITHVLP 352 + + INP + + V +KE + A A L +I P Sbjct: 270 ---SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYP 326 Query: 353 FEKINEGFDLL--HSGKSIRTVLTF 375 EK+ E + + SG + + +L Sbjct: 327 LEKVAEAHENIIHGSGATGKMILLL 351 >5VKT-A nrPDB Length = 362 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 87/362 (24%), Positives = 126/362 (34%), Gaps = 33/362 (9%) Query: 10 CKAAVLW---EVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TPLPVI 65 CK A W + S +V IK++ GIC TD HV+ PV+ Sbjct: 7 CKTAHGWAARDASGHLSPYSFSARIQGDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVV 66 Query: 66 LGHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124 GHE G+V VG GVT K GD V + F C C C NYC Sbjct: 67 PGHEVVGVVTDVGHGVTKFKAGDTVGVGYFVDSCRTCESCSTGHENYCP----------- 115 Query: 125 QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184 D H FS VV ++ V ++ + PL+ + C T Y Sbjct: 116 -DLVLTSNGVDHHHHGATTKGGFSDVLVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPM 174 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK-ELGATECIN 243 A PG V GLGG+G AV KA G + + + K +A LGA + Sbjct: 175 AQYALNEPGKHLGVVGLGGLGHMAVKFAKAFGM-TVTVISSSPGKRDEALGRLGADAFLV 233 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLS 303 D + +D + + + LL + G V+VG P L Sbjct: 234 SHDAAQMKAAAAT------LDGIIDTV-SAGHQIVPLLALLKPMGQMVVVGAPSTPLELP 286 Query: 304 INPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 ++ G+ G G + + DF + + V+ + +N + L Sbjct: 287 AYAIIT-GGKRVAGNGVGSVADCQAML----DFAGEHGVTADI--EVVQMDYVNTAIERL 339 Query: 364 HS 365 Sbjct: 340 EK 341 >3UOG-A nrPDB Length = 363 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 78/358 (21%), Positives = 130/358 (36%), Gaps = 39/358 (10%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL--PVILGHEAAGIVESVGE 79 + + V +++ ++ +AV + D V+ + L P + + +G+VE+VG+ Sbjct: 41 LKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSGVVEAVGK 100 Query: 80 GVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIH 139 VT +PGD+VI F P DG R T R Sbjct: 101 SVTRFRPGDRVISTFAPGW--------------------------LDGLRPGTGRTPAYE 134 Query: 140 HFLGT--STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 G S+Y V+ E + + + C T + + V + G Sbjct: 135 TLGGAHPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVV 194 Query: 198 VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 257 V G GGV L + KA GA +I +++K +A LGA IN + + ++ V Sbjct: 195 VQGTGGVALFGLQIAKATGA-EVIVTSSSREKLDRAFALGADHGIN-RLEEDWVERVYAL 252 Query: 258 MTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKG 317 D G D E+ G + L G ++GV + LLL +G Sbjct: 253 TGDRGADHILEIAGGAG--LGQSLKAVAPDGRISVIGVLEGFEVSGPVGPLLLKSPVVQG 310 Query: 318 AVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF 375 G ++ E + V + L +I F ++ E L G + V+ F Sbjct: 311 ISVGHRRALEDLVGAVD-----RLGLKPVIDMRYKFTEVPEALAHLDRGPFGKVVIEF 363 >5H83-A nrPDB Length = 360 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 80/363 (22%), Positives = 132/363 (36%), Gaps = 40/363 (11%) Query: 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVIL 66 +K + FS + +V+ K++ G C D + + +T P ++ Sbjct: 13 VKTFGFAAKDSSGFFSPFNFSRRATGENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVI 72 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 GHE G+V +G V K GDKV + F C KC +C N N C K + + Sbjct: 73 GHEIVGVVTEIGSKVQKFKVGDKVGVGGFVGACEKCEMCVNGVENNCSKVESTDG----H 128 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 G C VV+E PL + C T Y Sbjct: 129 FGNNFGGC--------------CNIMVVNEKYAVVWPENLPLHSGVPLLCAGITTYSPLR 174 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI--- 242 PG + GLGG+G A+ KA GA + K K ++ G + Sbjct: 175 RYGLDKPGLNIGIAGLGGLGHLAIRFAKAFGAKVTLISSSVKKKREALEKFGVDSFLLNS 234 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 NP++ + G +D + + ++ L + G +I+GVP + Sbjct: 235 NPEEMQGAY---------GTLDGIIDTMPVAHSI-VPFLALLKPLGKLIILGVPEEPFEV 284 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 P LL+ G+ G+ G K + + DF AK + + V+P + +N + Sbjct: 285 PA-PALLMGGKLIAGSAAGSMKETQEM----IDFAAKHNIVADV--EVIPIDYLNTAMER 337 Query: 363 LHS 365 + + Sbjct: 338 IKN 340 >3WLE-A nrPDB Length = 341 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 88/353 (24%), Positives = 150/353 (42%), Gaps = 46/353 (13%) Query: 26 DVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVK 85 D+ V PKA ++ +K+ AVG+C +D HV+ L ++GHE AG V +VG+ V K Sbjct: 28 DLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINYK 87 Query: 86 PGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTS 145 GD+V + CG C+ C+ N C KN G+ G DG Sbjct: 88 VGDRVACVGPNGCGGCKYCRGAIDNVC-KNAFGDWFGLGYDG------------------ 128 Query: 146 TFSQYTVV-DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGV 204 + QY +V +++I + T Y A+ +A+V+P S + G GG+ Sbjct: 129 GYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYH-AIKMAQVSPTSNILLIGAGGL 187 Query: 205 GLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G +A+ KA GA ++ +D K+ +AK+LGA + E L E G Sbjct: 188 GGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGAD----------AVYETLPESISPG-- 234 Query: 265 FSFEVIGRLDTMMASLLCCHE---ACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYG 321 SF ++ A+ C + G + VG+ + + ++ L L G+ +G Sbjct: 235 -SFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGD-LALREIRILGSFWG 292 Query: 322 GFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK-SIRTVL 373 + + KLV++ + ++ +++ E + L + R V Sbjct: 293 TTNDLDDVLKLVSE-----GKVKPVVRSA-KLKELPEYIEKLRNNAYEGRVVF 339 >1Q1N-A nrPDB Length = 360 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 81/370 (21%), Positives = 138/370 (37%), Gaps = 35/370 (9%) Query: 12 AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVT-PLPVILGHEA 70 A E K + P +++ IK+ A G+C +D H +G+ +P+++GHE Sbjct: 11 AIQSHEDWKNPKKTKYDPKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEI 70 Query: 71 AGIVESVGEGV-TTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT 128 G V +G + +K G +V + C +C CKN YC K + +DG Sbjct: 71 VGKVVKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKF-VTTYSQPYEDG- 128 Query: 129 RRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 ++ ++ Y V E+ V I P + CG T Y V Sbjct: 129 ------------YVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNG 176 Query: 189 KVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 PG + GLGG+G + KA GA + + + K A ++GA I + Sbjct: 177 C-GPGKKVGIVGLGGIGSMGTLISKAMGAETYV-ISRSSRKREDAMKMGADHYIATLEEG 234 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTM-MASLLCCHEACGTSVIVGVPPASQNLSINPM 307 ++ D L + + + G V + +P + LS+ P Sbjct: 235 DWGEKYF-----DTFDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPY 289 Query: 308 LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEK--INEGFDLLHS 365 L + + G K + KLV++ K + LP + ++E F+ + Sbjct: 290 G-LKAVSISYSALGSIKELNQLLKLVSEKDIK------IWVETLPVGEAGVHEAFERMEK 342 Query: 366 GKSIRTVLTF 375 G +R T Sbjct: 343 G-DVRYRFTL 351 >2DPH-A nrPDB Length = 398 Score = 180 bits (456), Expect = 9e-46, Method: Composition-based stats. Identities = 93/402 (23%), Positives = 151/402 (37%), Gaps = 56/402 (13%) Query: 13 AVLWEVKKPFSIEDVEVAPPK------AYEVRIKMVAVGICRTDDHVVSGNLVTPLPVIL 66 +V++ + +E V + + V +K+V+ IC +D H+ G + P +L Sbjct: 5 SVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPKGHVL 64 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 GHE G V G V + GD V F CG+CR CK S+ C N + Sbjct: 65 GHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADL--- 121 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDEN---AVAKIDAASPLEKV---CLIGCGFSTG 180 G F +G ++Y +V + D +EK+ LI TG Sbjct: 122 GAFGFDLKGWS-------GGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTG 174 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG--A 238 + V+ A V PGS + G G VG A G + GAA +I D N ++ + G Sbjct: 175 FHGCVS-AGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFET 233 Query: 239 TECINPQDYKKPIQEVL-KEMTDGGVD-FSFEVIG--------RLDTMMASLLCCHEACG 288 + N + I ++L K D GVD FE G + + SL A G Sbjct: 234 IDLRNSAPLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAGG 293 Query: 289 TSVIVGVPPASQNLSIN------PMLLLTGRTWKGAVYG----------GFKSKEGIPKL 332 I G+ S +N + L G+ W ++ E I Sbjct: 294 AIGIPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNRHLTEAILWD 353 Query: 333 VADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLT 374 +++K +++ V+ ++ +G+ G + V+ Sbjct: 354 QMPYLSKVMNIE-----VITLDQAPDGYAKFDKGSPAKFVID 390 >3QWB-A nrPDB Length = 334 Score = 178 bits (452), Expect = 3e-45, Method: Composition-based stats. Identities = 85/363 (23%), Positives = 124/363 (34%), Gaps = 66/363 (18%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGV 81 ED V E+ IK G+ + + G P +LG EA+G V + G+GV Sbjct: 23 IKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGV 82 Query: 82 TTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHF 141 T + GD+V + Sbjct: 83 TNFEVGDQVA-------------------------------------------------Y 93 Query: 142 LGTSTFSQY-TVVDENAVAKIDAASPLEKVCLIGCGFS---TGYGSAVNVAKVTPGSTCA 197 + STF+QY + + V K+ + E++ L G T V G Sbjct: 94 ISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVL 153 Query: 198 VFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 +F GGVGL K GA IAV +K AKE GA IN + +++VLK Sbjct: 154 LFAAAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLK 211 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPA-SQNLSINPMLLLTGRTW 315 GVD SF+ +G+ DT SL + G V G SI + Sbjct: 212 FTNGKGVDASFDSVGK-DTFEISL-AALKRKGVFVSFGNASGLIPPFSITRLSPKNITLV 269 Query: 316 KGAVYGGFKSKEGIPKLVADFM----AKKFSLDALITHVLPFEKINEGFDLLHSGKS-IR 370 + +YG E +F +KK ++ I P + S K+ + Sbjct: 270 RPQLYGYIADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESRKTVGK 327 Query: 371 TVL 373 VL Sbjct: 328 LVL 330 >4JLW-A nrPDB Length = 399 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 88/394 (22%), Positives = 155/394 (39%), Gaps = 52/394 (13%) Query: 20 KPFSIEDVEVAPPK---------AYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEA 70 P +E + PK + V +++V+ IC +D H+V G P ++LGHE Sbjct: 11 GPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEI 70 Query: 71 AGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRR 130 G V +G GV T+K GD V F CG CR CK + CL + G Sbjct: 71 TGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVN-----PARAGGAYG 125 Query: 131 FTCRGKPIHHFLGTSTFSQYTVVD--ENAVAKID-AASPLEKVCLIGC---GFSTGYGSA 184 + G + ++Y +V + + K+ + +EK+ + C TGY A Sbjct: 126 YVDMGGWV------GGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGA 179 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 V A V PGST + G G VGL+A + GAA +I D+N + A AK+ G Sbjct: 180 V-TAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLS 238 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIG--------------RLDTMMASLLCCHEACGTS 290 +D +++ + + VD + + +G T++ SL+ G Sbjct: 239 KDTPL-HEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPATVLNSLMGITRVAGKI 297 Query: 291 VIVGVPPASQNLSINPMLLLTGRTWKGAV---------YGGFKSKEGIPKLVADFMAKKF 341 I G+ +++ + + + G + +L+ M + Sbjct: 298 GIPGLYVTEDPGAVDAAAKHGALSIRFGLGWAKSHSFHTGQTPVMKYNRQLMQAIMWDRI 357 Query: 342 SLDALI-THVLPFEKINEGFDLLHSGKSIRTVLT 374 + ++ V+ + +G+ +G + V+ Sbjct: 358 KIADIVGVEVITLDDAPKGYGEFDAGVPKKFVID 391 >1WLY-A nrPDB Length = 333 Score = 176 bits (446), Expect = 2e-44, Method: Composition-based stats. Identities = 80/384 (20%), Positives = 139/384 (36%), Gaps = 77/384 (20%) Query: 12 AAVLWEVKKP--FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL-----PV 64 AAV+ + P F E+V+V P +VR++ A+G+ D + +G + PL P+ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAG-IPHPLVVGEPPI 62 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124 ++G EAA +VE VG GVT G++V P Sbjct: 63 VVGFEAAAVVEEVGPGVTDFTVGERVCTCLPP---------------------------- 94 Query: 125 QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCG--FSTGYG 182 +SQ + + K+ L+ V L G T Sbjct: 95 -------------------LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQY 135 Query: 183 SAVNVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 KV PG + GG+G V + GA +I ++K A++LG Sbjct: 136 LLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGA-TVIGTVSTEEKAETARKLGCHHT 194 Query: 242 INPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 IN + EV++E+T G GVD ++ IG+ DT+ SL C G G Sbjct: 195 INYS--TQDFAEVVREITGGKGVDVVYDSIGK-DTLQKSLD-CLRPRGMCAAYGHASGVA 250 Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADF---------MAKKFSLDALITHVL 351 +P+ ++ +G+++ + ++ K L + + Sbjct: 251 ----DPIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFDAVKAGVLHSSVAKTF 306 Query: 352 PFEKINEGFDLLHSGKSIRTVLTF 375 P + + ++I +++ Sbjct: 307 PLREAAAAHKYMGGRQTIGSIVLL 330 >6C49-A nrPDB Length = 350 Score = 168 bits (426), Expect = 3e-42, Method: Composition-based stats. Identities = 69/368 (18%), Positives = 130/368 (35%), Gaps = 39/368 (10%) Query: 9 KCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILG 67 +A + + + + ++V +K+ G+C +D V++ T PV+ G Sbjct: 13 TIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAG 72 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 HE G + ++G ++ G +V I C C C + C ++ G Sbjct: 73 HEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVGH--- 129 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 F+ + E + CG T + + Sbjct: 130 -----------------AGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLK 172 Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 K+ V G+GG+G A+ KA G I A N DK + K +GA +N +D Sbjct: 173 H-KIQATHHVGVIGIGGLGHIAIKLLKAWG-CEITAFSSNPDKTEELKAMGADHVVNSRD 230 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 + + G D + + + + G+ +G+ +S+ Sbjct: 231 TEAVKAQ------KGKFDLLLSTV-NVTLNWRAFISTLAPNGSLHFLGLTLEPVPVSVG- 282 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 L+ ++ G+ G + + K A + + I + P ++NE + LHSG Sbjct: 283 SLIDGAKSVTGSPTGSPAALRQLLKF-----AARKKIAPQI-ELFPMSQLNEAIERLHSG 336 Query: 367 KS-IRTVL 373 ++ R VL Sbjct: 337 QARYRIVL 344 >1KOL-A nrPDB Length = 398 Score = 167 bits (422), Expect = 9e-42, Method: Composition-based stats. Identities = 86/397 (21%), Positives = 154/397 (38%), Gaps = 48/397 (12%) Query: 14 VLWEVKKPFSIEDVEVAPPKA-------YEVRIKMVAVGICRTDDHVVSGNLVTPLPVIL 66 V++ ++ ++ + + V +K+V+ IC +D H+V G + ++L Sbjct: 6 VVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGLVL 65 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 GHE G V G V ++ GD V F CG+CR CK + CL + Sbjct: 66 GHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVN-----PARAG 120 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVD--ENAVAKIDA-ASPLEKVCLIGC---GFSTG 180 G + G T ++Y +V + + K+ +EK+ + C TG Sbjct: 121 GAYGYVDMGDW------TGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTG 174 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG--- 237 Y AV A V PGST V G G VGL+A + GAA +I D+N + A AK G Sbjct: 175 YHGAV-TAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEI 233 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVD-FSFEVIGR---------LDTMMASLLCCHEAC 287 A ++ +++ + + D VD FE G T++ SL+ Sbjct: 234 ADLSLDTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVA 293 Query: 288 GTSVIVGVPPASQNLSINPMLLLTGRTWKGAV-----YGGFKSKEGIPKLVADFMAK--- 339 G I G+ +++ + + + + + + + K M Sbjct: 294 GKIGIPGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMW 353 Query: 340 -KFSLDALI-THVLPFEKINEGFDLLHSGKSIRTVLT 374 + ++ ++ V+ + G+ +G + V+ Sbjct: 354 DRINIAEVVGVQVISLDDAPRGYGEFDAGVPKKFVID 390 >1QOR-A nrPDB Length = 327 Score = 159 bits (401), Expect = 3e-39, Method: Composition-based stats. Identities = 83/361 (22%), Positives = 130/361 (36%), Gaps = 63/361 (17%) Query: 16 WEVKKPFSIEDVEVAP--PKAYEVRIKMVAVGICRTDDHVVSGNLVTP-LPVILGHEAAG 72 + P ++ VE P P E++++ A+GI D ++ SG P LP LG EAAG Sbjct: 8 HKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAG 67 Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 IV VG GV +K GD+V+ Sbjct: 68 IVSKVGSGVKHIKAGDRVV----------------------------------------- 86 Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 + +S + + A + AA E+ T Y ++ P Sbjct: 87 ------YAQSALGAYSSVHNIIADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKP 140 Query: 193 GSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 GGVGL A KA GA ++I K A + GA + IN ++ + + Sbjct: 141 DEQFLFHAAAGGVGLIACQWAKALGA-KLIGTVGTAQKAQSALKAGAWQVINYRE--EDL 197 Query: 252 QEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN------LSI 304 E LKE+T G V ++ +GR DT SL C G V G + L+ Sbjct: 198 VERLKEITGGKKVRVVYDSVGR-DTWERSLDCLQRR-GLMVSFGNSSGAVTGVNLGILNQ 255 Query: 305 NPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLH 364 L +T + +G + + E +L + + +D P + ++L Sbjct: 256 KGSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILE 315 Query: 365 S 365 S Sbjct: 316 S 316 >4RVS-A nrPDB Length = 329 Score = 157 bits (396), Expect = 8e-39, Method: Composition-based stats. Identities = 69/377 (18%), Positives = 124/377 (32%), Gaps = 65/377 (17%) Query: 12 AAVLWEVKKPFSIEDVEVAPPKAY--EVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHE 69 A + E P + V+ P+ E+ IK A+G+ D + SG LP ++G E Sbjct: 4 AIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSE 63 Query: 70 AAGIVESVGEGVTT----VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 G VE+VG GVT + GD+V+ Sbjct: 64 VCGTVEAVGPGVTAADTAISVGDRVVSASA------------------------------ 93 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 ++++ + AK+ E T + Sbjct: 94 ------------------NGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLK 135 Query: 186 NVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 +V V G T V G GGVGL G R+I +K +K+ GA ++ Sbjct: 136 SVYPVKRGDTVLVHAGAGGVGLILTQWATHLGV-RVITTVSTAEKAKLSKDAGADVVLDY 194 Query: 245 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLS 303 + ++E+T G GV ++ +G T + L GT + G Sbjct: 195 PEDAWQFAGRVRELTGGTGVQAVYDGVGA--TTFDASLASLAVRGTLALFGAASGPVP-P 251 Query: 304 INPMLLLTGRTW---KGAVYGGFKSKEGIPKLVADFMAKKFS--LDALITHVLPFEKINE 358 ++P L + + +++ ++ E A+ + + + P Sbjct: 252 VDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGNEAITVAVGGRYPLADALR 311 Query: 359 GFDLLHSGKSIRTVLTF 375 L + K++ +V+ Sbjct: 312 AHQDLEARKTVGSVVLL 328 >2VCY-A nrPDB Length = 344 Score = 155 bits (392), Expect = 3e-38, Method: Composition-based stats. Identities = 75/369 (20%), Positives = 135/369 (36%), Gaps = 64/369 (17%) Query: 20 KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV--TPLPVILGHEAAGIVESV 77 K ++++E+A + +VR+KM+A I +D +++ GN LP + G+E V +V Sbjct: 27 KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAV 86 Query: 78 GEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137 G VT +KPGD VIP Sbjct: 87 GSNVTGLKPGDWVIPANA------------------------------------------ 104 Query: 138 IHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 G T+ V E A+ ++ + PL+ +G T Y ++ ++ PG + Sbjct: 105 -----GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 159 Query: 198 -VFGLGGVGLSAVMGCKAAGAARIIAVDINKD--KF-AKAKELGATECINPQDYKKP-IQ 252 GVG + + A G I V D K + K LGA I ++ ++P ++ Sbjct: 160 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMK 219 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTG 312 K+M + +G + LL GT V G ++ +L+ Sbjct: 220 NFFKDMPQP--RLALNCVGGKSS--TELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKD 275 Query: 313 RTWKGAVYGGFK---SKEGIPKLVADF--MAKKFSLDALITHVLPFEKINEGFDL-LHSG 366 +G +K S + +L+ + ++ L A +P + + + Sbjct: 276 LKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPF 335 Query: 367 KSIRTVLTF 375 S + +LT Sbjct: 336 ISSKQILTM 344 >2CF5-A nrPDB Length = 357 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 80/346 (23%), Positives = 136/346 (39%), Gaps = 30/346 (8%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL-VTPLPVILGHEAAGIVESVGEG 80 S + +V I+++ GIC TD H +L ++ P++ GHE G V VG Sbjct: 22 LSPYTYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEVVEVGSD 81 Query: 81 VTTVKPGD-KVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIH 139 V+ GD + CG C C+ YC K + ++ I+ Sbjct: 82 VSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPK--------------KIWSYNDVYIN 127 Query: 140 HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF 199 F++ TVV + V KI +E+ + C T Y + PG + Sbjct: 128 GQPTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGIL 187 Query: 200 GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 GLGGVG V KA G + NK + ++LGA + + D Q + E+ Sbjct: 188 GLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSD-----QAKMSELA 242 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAV 319 D +D+ + + + L + G +++GV + P+L+L + G+ Sbjct: 243 DS-LDYVIDTVPVHHALEPYL-SLLKLDGKLILMGVINNPLQF-LTPLLMLGRKVITGSF 299 Query: 320 YGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 G K E + + K+ L ++I V+ + +N F+ L Sbjct: 300 IGSMKETEEMLEFC-----KEKGLSSII-EVVKMDYVNTAFERLEK 339 >3FBG-A nrPDB Length = 346 Score = 148 bits (373), Expect = 5e-36, Method: Composition-based stats. Identities = 59/300 (19%), Positives = 105/300 (35%), Gaps = 66/300 (22%) Query: 18 VKKPFSIED--------VEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHE 69 ++PF + D +++ PK +E+ +K+ ++ + D + V+ P +LG + Sbjct: 8 FEQPFKLSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD-VSKAPRVLGFD 66 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTR 129 A G+VESVG VT GD V +P Sbjct: 67 AIGVVESVGNEVTMFNQGDIVYYSGSPD-------------------------------- 94 Query: 130 RFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 + ++Y +++E VAK E+ + T Y + +V Sbjct: 95 -------------QNGSNAEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFG 141 Query: 190 VT------PGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 ++ G T + G GGVG A KA G R+I + K++GA + Sbjct: 142 ISRNRNENEGKTLLIINGAGGVGSIATQIAKAYG-LRVITTASRNETIEWTKKMGADIVL 200 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 N + + + K VD+ F D ++ + G + Q+L Sbjct: 201 NHK---ESLLNQFKTQGIELVDYVF-CTFNTDMYYDDMIQLVKPRGHIATIVAFENDQDL 256 >3JYN-A nrPDB Length = 325 Score = 147 bits (371), Expect = 8e-36, Method: Composition-based stats. Identities = 78/370 (21%), Positives = 130/370 (35%), Gaps = 68/370 (18%) Query: 18 VKKPFSIEDVEVAP--PKAYEVRIKMVAVGICRTDDHVVSGNLVTP-LPVILGHEAAGIV 74 V P +E V+ P P V ++ A+G+ D + SG P LP LG E AG+V Sbjct: 10 VGGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVV 69 Query: 75 ESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCR 134 E+VG+ VT RF Sbjct: 70 EAVGDEVT-----------------------------------------------RFKVG 82 Query: 135 GKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194 + + +S+ V+ E + K+ + E+ + T +V PG Sbjct: 83 DRVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGE 142 Query: 195 TCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 GGVG A KA GA ++I + +K A AK LGA E I+ + + + Sbjct: 143 IILFHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDYS--HEDVAK 199 Query: 254 VLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTG 312 + E+TDG ++ +G DT + SL G V G + +N +L Sbjct: 200 RVLELTDGKKCPVVYDGVG-QDTWLTSLDSVAPR-GLVVSFG-NASGPVSGVNLGILAQK 256 Query: 313 ------RTWKGAVYGGFKSKEGI-PKLVADFMAKKFSLDALITHVLPFEKINEG-FDLLH 364 R G+ ++ + + +L + K +D + + + +L Sbjct: 257 DSVYVTRPTLGSYANNAQNLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELSA 314 Query: 365 SGKSIRTVLT 374 + T+L Sbjct: 315 RRTTGSTILI 324 >3B70-A nrPDB Length = 371 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 73/369 (19%), Positives = 122/369 (33%), Gaps = 70/369 (18%) Query: 23 SIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVT 82 +V +++ AV I +D + G TP LG + AG V +VG VT Sbjct: 25 VWNAAPCPMLPRDQVYVRVEAVAINPSDTKMR-GQFATPW-AFLGTDYAGTVVAVGSDVT 82 Query: 83 TVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFL 142 ++ GD+V C Sbjct: 83 HIQVGDRVYGAQNEMC----------------------------------------PRTP 102 Query: 143 GTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV---------AKVTPG 193 FSQYTV AKI E+ + G ST G A+ + A P Sbjct: 103 DQGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTA-GLAMKLLGLPLPSPSADQPPT 161 Query: 194 ST--CAVFGLGGVGLSAVMGCKAAGAARIIAVDI-NKDKFAKAKELGATECINPQDYKKP 250 + V GG +A + + + I + + F AK GA E + + Sbjct: 162 HSKPVYVLVYGGSTATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVFDYRAPN-- 219 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPA--------SQNL 302 + + ++ T + ++ + I +++ A G V + P + + Sbjct: 220 LAQTIRTYTKNNLRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTDW 279 Query: 303 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADF--MAKKFSLDALITHVLPFEKINEGF 360 ++ P + G TW A YG S+E + D +A + D + H P + GF Sbjct: 280 TLGPTIFGEGSTWP-APYGRPGSEEER-QFGEDLWRIAGQLVEDGRLVH-HPLRVVQGGF 336 Query: 361 DLLHSGKSI 369 D + G + Sbjct: 337 DHIKQGMEL 345 >2OBY-A nrPDB Length = 338 Score = 137 bits (345), Expect = 7e-33, Method: Composition-based stats. Identities = 75/371 (20%), Positives = 124/371 (33%), Gaps = 66/371 (17%) Query: 19 KKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPV--ILGHEAAGIVES 76 + +++V P EV +K+ A + R D G P ILG EA+G V Sbjct: 18 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 77 Query: 77 VGEGVT-TVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRG 135 +G G K GD + L Sbjct: 78 LGPGCQGHWKIGDTAMAL------------------------------------------ 95 Query: 136 KPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195 L +QY V E + I L + I + T + V V G Sbjct: 96 ------LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDY 149 Query: 196 CAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + GL GVG +A+ + AGA + ++ K A++LGA N + + + Sbjct: 150 VLIHAGLSGVGTAAIQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKK-EDFSEAT 207 Query: 255 LKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG-VPPASQNLSINPMLLLTGR 313 LK GV+ + IG + + C G V+ G + N + LL Sbjct: 208 LKFTKGAGVNLILDCIGG--SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRG 265 Query: 314 TWKGAVYGGF--KSKEGIPKLVADFMAKKFS------LDALITHVLPFEKINEGFDLLHS 365 + ++ K K+ + + + FS L ++ + P +I E + + Sbjct: 266 SLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 325 Query: 366 GKSI-RTVLTF 375 K+I + VL Sbjct: 326 NKNIGKIVLEL 336 >3HZZ-A nrPDB Length = 467 Score = 135 bits (340), Expect = 3e-32, Method: Composition-based stats. Identities = 74/392 (18%), Positives = 130/392 (33%), Gaps = 71/392 (18%) Query: 20 KPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHV-------------VSGNLV-----TP 61 K +++V V E + ++A + G L Sbjct: 74 KSIHLDEVPVPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHD 133 Query: 62 LPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 LP I+G + AG+V G GV +PGD+V+ +CL +L +P Sbjct: 134 LPYHIIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELESP 175 Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + ++ +V N + E+ G ST Sbjct: 176 DGHDDTMLDPE---QRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTA 232 Query: 181 YGSAV--NVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 Y V N A + G ++G GG+G A AG A I V + K + +G Sbjct: 233 YRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFA-LAGGANPICVVSSPQKAEICRSMG 291 Query: 238 ATECI----------------NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 A I +P+++K+ + + + +D FE GR +T AS+ Sbjct: 292 AEAIIDRNAEGYKFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGR-ETFGASVY 350 Query: 282 CCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKF 341 + GT + N L ++ + G+ + ++ +L+A K Sbjct: 351 VTRKG-GTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIA-----KG 404 Query: 342 SLDALITHVLPFEKINEG----FDLLHSGKSI 369 + ++ E+ + LH GK Sbjct: 405 KIHPTLSKTYSLEETGQAAYDVHRNLHQGKVG 436 >4J6F-A nrPDB Length = 382 Score = 131 bits (329), Expect = 5e-31, Method: Composition-based stats. Identities = 64/369 (17%), Positives = 112/369 (30%), Gaps = 59/369 (15%) Query: 25 EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP-----------------LPVILG 67 DV V P A EV IK+ A G+ TD V G T P I G Sbjct: 52 RDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLTFPRIQG 111 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127 + G + +VGEGV + G++V+ F+ Sbjct: 112 TDTVGHIVAVGEGVDRARIGERVMVDFSIY-----------------------------N 142 Query: 128 TRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +++Y + + ++ C + TG + Sbjct: 143 RDDDSLADIDYMGHGRDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTG-ERMLER 201 Query: 188 AKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A++ G T V G GGVG + + +A GA I K A ++GA + + Sbjct: 202 ARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAG--PGKEAAMLDIGAQAVVT-RG 258 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306 + V +D +++G + LL G G Sbjct: 259 QGDLAEAVEAASGGRPIDVVADLVGGP--LFNDLLKILRPEGRYTTAGAIAGPVVQLDLR 316 Query: 307 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG-FDLLHS 365 + L G+ G + + + + + L+ V P + + D + Sbjct: 317 TMYLKQLELHGSSQGSRADFRRLVRYIEEK-----KIRPLVGGVYPLSEFHRAQTDFMAK 371 Query: 366 GKSIRTVLT 374 + V+ Sbjct: 372 NFVGKLVVV 380 >4A27-A nrPDB Length = 349 Score = 129 bits (323), Expect = 3e-30, Method: Composition-based stats. Identities = 68/395 (17%), Positives = 123/395 (31%), Gaps = 83/395 (21%) Query: 8 IKCKAAVLWEVKK--PFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL--VTPLP 63 ++ +A VL + + P+ E++I++ A G+ D V GN+ P Sbjct: 2 MEMRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTP 61 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGT 123 ++ G E +GIVE++G+ V + GD+V+ VC E Y Sbjct: 62 LVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVY------------ 109 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 KI + F T Y Sbjct: 110 ------------------------------------KIPDDMSFSEAAAFPMNFVTAYVM 133 Query: 184 AVNVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 VA + G + V GGVG + C + K K Sbjct: 134 LFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTAST-FKHEAIK----DSVT 188 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG----VPPA 298 + D + +K ++ GVD + + +T L + GT ++ G V Sbjct: 189 HLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKG--LSLLKPLGTYILYGSSNMVTGE 246 Query: 299 SQNL-----------SINPMLLLTG-RTWKGAVYGGFKSKEGIPKLVADFMAKKF----- 341 +++ +NP+ L + G K+G L+ + K Sbjct: 247 TKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQ 306 Query: 342 -SLDALITHVLPFEKINEGFDLLH-SGKSIRTVLT 374 + ++ + E++ E +H G + +L Sbjct: 307 KKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILD 341 >3SLK-A nrPDB Length = 795 Score = 128 bits (322), Expect = 4e-30, Method: Composition-based stats. Identities = 69/356 (19%), Positives = 108/356 (30%), Gaps = 60/356 (16%) Query: 22 FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGV 81 E AP EVRI M A G+ D + G P LG E AG+V G GV Sbjct: 226 LVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMY--PGVASLGSEGAGVVVETGPGV 283 Query: 82 TTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHF 141 T + PGD+V+ + Sbjct: 284 TGLAPGDRVMGMIPKA-------------------------------------------- 299 Query: 142 LGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-G 200 F V D V +I A + + F T Y + V++A + PG + V Sbjct: 300 -----FGPLAVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSA 354 Query: 201 LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 GGVG++A+ + GA + A +A EL + + Q+ L Sbjct: 355 AGGVGMAAIQLARHLGA-EVYATASEDK--WQAVELSREHLASSRTC-DFEQQFLGATGG 410 Query: 261 GGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVY 320 GVD + + L G + +G + + V Sbjct: 411 RGVDVVLNSLAGE--FADASLRMLPRGGRFLELGKTDVRDPVEVADAHPGVSYQAFDTVE 468 Query: 321 GGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS-IRTVLTF 375 G + + + + + L+ L + E L + + VLT Sbjct: 469 AGPQRIGEMLHELVELFEGRV-LEPLPVTAWDVRQAPEALRHLSQARHVGKLVLTM 523 >4A10-A nrPDB Length = 447 Score = 124 bits (311), Expect = 7e-29, Method: Composition-based stats. Identities = 71/387 (18%), Positives = 119/387 (30%), Gaps = 67/387 (17%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDD----------------HVV 54 K +V+K + +V + EV + ++A I + Sbjct: 39 KGVADKDVRKSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNAR 98 Query: 55 SGNLVTPL--PV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNY 111 G T P +LG + +G+V G GV KPGD VI Sbjct: 99 QGGWATRHDQPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHPA---------------- 142 Query: 112 CLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVC 171 + T DG R G ++Y VV + + A E+ Sbjct: 143 ---HVDEQEPATHGDGMLGTEQRAWGFETNFG--GLAEYGVVRASQLLPKPAHLTWEEAA 197 Query: 172 LIGCGFSTGYGSAV--NVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKD 228 + T Y V A++ G ++G GG+G A+ K G + V + Sbjct: 198 VSPLCAGTAYRMLVSDRGAQMKQGDIVLIWGASGGLGSYAIQFVKNGGGIPVAVV-SSAQ 256 Query: 229 KFAKAKELGATECINPQDY-------KKP---------IQEVLKEMTDGGVDFSFEVIGR 272 K A + LG IN + P + +++ E D FE GR Sbjct: 257 KEAAVRALGCDLVINRAELGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGR 316 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKL 332 + + GT V G + N L + + G+ + ++ +L Sbjct: 317 V--TFGLSVIVARRGGTVVTCGSSSGYLHTFDNRYLWMKLKKIVGSHGANHEEQQATNRL 374 Query: 333 VADFMAKKFSLDALITHVLPFEKINEG 359 + ++ V P + E Sbjct: 375 FESGA-----VVPAMSAVYPLAEAAEA 396 >3TQH-A nrPDB Length = 321 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 71/376 (18%), Positives = 129/376 (34%), Gaps = 76/376 (20%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPK--AYEVRIKMVAVGICRTDDHVVSG------NLVTPL 62 KA + P ++ V+ P+ ++ IK+ A + D +G L L Sbjct: 8 KAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKNNL 67 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG 122 P LG++ +G V +G V V GDKV+ + C C Sbjct: 68 PSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C------------------ 107 Query: 123 TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 +++Y + + + + + T Sbjct: 108 ------------------------YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTAL- 142 Query: 183 SAVNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A+N A+V G + G GGVG A+ K G + +K A K LGA +C Sbjct: 143 QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKG--TTVITTASKRNHAFLKALGAEQC 200 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 IN + ++ L ++ VD +++G + + + C + G V V A + Sbjct: 201 INYHE-----EDFLLAISTP-VDAVIDLVGGDVGIQS--IDCLKETGCIVSVPTITAGRV 252 Query: 302 LSINPMLLLTGRTWKGAVYGGFK--SKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 + + + +G K + E + L K ++ I+ + + Sbjct: 253 IEV-------AKQKHRRAFGLLKQFNIEELHYLGKLVSEDKLRIE--ISRIFQLSEAVTA 303 Query: 360 FDLLHSGKSIRTVLTF 375 +LL +G +R L F Sbjct: 304 HELLETGH-VRGKLVF 318 >4DVJ-A nrPDB Length = 363 Score = 119 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 61/311 (19%), Positives = 105/311 (33%), Gaps = 62/311 (19%) Query: 1 MSTAGKVIKCKAAVLWEVKKPF----SIEDVEVAPPKA--YEVRIKMVAVGICRTDDHVV 54 + T + AV + P S+ D+E+ P +++ +++ AV + D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 55 SGNLVTPLPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCL 113 ++G++AAGIV +VG VT +PGD+V + Sbjct: 73 RSTPPDGTDWKVIGYDAAGIVSAVGPDVTLFRPGDEVFYAGSI----------------- 115 Query: 114 KNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLI 173 + T +++ +VDE V + + + Sbjct: 116 ----------------------------IRPGTNAEFHLVDERIVGRKPKTLDWAEAAAL 147 Query: 174 GCGFSTGYGSAVNVAKVT---PGSTCAVF---GLGGVGLSAVMGCKAAGAARIIAVDINK 227 T + + + V PG+ A+ G GGVG AV + +IA Sbjct: 148 PLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIATASRP 207 Query: 228 DKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEAC 287 + K LGA I D+ KP+ + + G F F D A + Sbjct: 208 ETQEWVKSLGAHHVI---DHSKPLAAEVAALGLGAPAFVFSTT-HTDKHAAEIADLIAPQ 263 Query: 288 GTSVIVGVPPA 298 G ++ P A Sbjct: 264 GRFCLIDDPSA 274 >4Y1B-A nrPDB Length = 425 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 75/404 (18%), Positives = 135/404 (33%), Gaps = 68/404 (16%) Query: 1 MSTAGKVIKCKAAVLWEVKKP---FSIEDVEVAPPKAYEVRIKMVAVGICRT-------- 49 + TA K + +P F E V+V P +V +K++A G+ Sbjct: 34 LGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGE 93 Query: 50 --DDHVVSGNLVTPLPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKN 106 D I G + +GIV +VG+GV +KPG +V+ L Sbjct: 94 PLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGV-RLKPGAEVVVLA------------ 140 Query: 107 PESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASP 166 C ++ D T R +F+Q+ VVDE Sbjct: 141 -----CRWDESAQDIRLGADPVTSSTQRVWGYEE--NYGSFAQFAVVDEYMCHPKPQRLS 193 Query: 167 LEKVCLIGCGFSTGYGSA--VNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAV 223 +T Y V PG ++ G GG+G A+ + G + V Sbjct: 194 WAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVV 253 Query: 224 DINKDKFAKAKELGATECINPQDYKKPI-------QEVLKEMTDG--------------- 261 ++++ LGA I+ +++ +E +K+ DG Sbjct: 254 -SSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGER 312 Query: 262 -GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVY 320 E G DT+ S+ A + G + ++ + L + + +G+ Sbjct: 313 RAPRIVLEHSG-ADTIPTSIYMADNAGMVVICGGTTGYNGDVDLR-FLWMRQKRLQGSHA 370 Query: 321 GGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLH 364 + I +L+ + ++D ++ FE+I L+H Sbjct: 371 ASAREAREITRLID-----QGAIDPCLSRTFGFEEIGLAHQLIH 409 >2VN8-A nrPDB Length = 375 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 77/414 (18%), Positives = 133/414 (32%), Gaps = 95/414 (22%) Query: 1 MSTAGKVIKCKAAVLWEVKKPFSI---EDVEVAPPK-AYEVRIKMVAVGICRTDDHVVSG 56 + T + A V+ + K + +++ + EV +K+ A + D ++ SG Sbjct: 13 LGTENLYFQSMAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSG 72 Query: 57 NLVT----------------PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGK 100 T P+ LG + +G+V G V KPGD+V P Sbjct: 73 YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW--- 129 Query: 101 CRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAK 160 T S++ VV N V+ Sbjct: 130 ------------------------------------------KQGTLSEFVVVSGNEVSH 147 Query: 161 IDAASPLEKVCLIGCGFSTGYGSAVNVAKV----TPGSTCAVFGL-GGVGLSAVMGCKAA 215 + + + T + + V + G + G GGVG A+ KA Sbjct: 148 KPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAW 207 Query: 216 GAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 A + AV ++LGA + I+ + ++E LK + DF + +G Sbjct: 208 DA-HVTAVCSQDAS-ELVRKLGADDVIDYK--SGSVEEQLKSL--KPFDFILDNVGGSTE 261 Query: 276 MMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKL--- 332 A + T V + P L+++ + + G G G K + Sbjct: 262 TWAPDFLKKWSGATYVTLVTP---FLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYR 318 Query: 333 VADFMAK------------KFSLDALITHVLPFEKINEGFDLLHSGKS-IRTVL 373 A FMA + +I PF K+ E F + G + +TV+ Sbjct: 319 WAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 372 >2CDC-A nrPDB Length = 366 Score = 118 bits (295), Expect = 5e-27, Method: Composition-based stats. Identities = 68/379 (17%), Positives = 134/379 (35%), Gaps = 29/379 (7%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKA-YEVRIKMVAVGICRTDDHVVSGNLV-TPLP----- 63 KA ++ ++DV+ + +++I+ + GIC D +V+G L + LP Sbjct: 2 KAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKDF 61 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGT 123 ++LGHEA G+VE G GD V+P+ CG CR C ++C + G Sbjct: 62 LVLGHEAIGVVEESYHG---FSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIH 118 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 DG R P + + ++ + +A I+ + T Sbjct: 119 KMDGFMREWWYDDPKYLVKIPKSIEDIGILAQP-LADIEKSIEEILEVQKRVPVWTCDDG 177 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAK-AKELGATECI 242 +N V G G +G+ + + G +A + + E T Sbjct: 178 TLNC------RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTNYY 231 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ-- 300 N + +++ + G D + G ++ +++ G + G + Sbjct: 232 NSSNGYDKLKDSV-----GKFDVIIDATGADVNILGNVIPLLGRNGVLGLFGFSTSGSVP 286 Query: 301 -NLSINPMLLLTGRTWKGAVYGG-FKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINE 358 + ++ T +T G V G ++ + L + + LIT + E Sbjct: 287 LDYKTLQEIVHTNKTIIGLVNGQKPHFQQAVVHLASWKTLYPKAAKMLITKTVSINDEKE 346 Query: 359 GFDLLHSGK--SIRTVLTF 375 +L + I+ + + Sbjct: 347 LLKVLREKEHGEIKIRILW 365 >4IDE-A nrPDB Length = 332 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 78/373 (20%), Positives = 126/373 (33%), Gaps = 78/373 (20%) Query: 11 KAAVLWEVKKPFSI----EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV---TPLP 63 KA V E K + V V K +V IK+VA + D G +PLP Sbjct: 25 KAWVYSEYGKTSDVLKFDPSVAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLP 84 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGT 123 I G++ AG+V VG VT K GD+V Sbjct: 85 TIPGYDVAGVVVKVGSQVTKFKVGDEVYG------------------------------- 113 Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + + + ++YT DE +A + + T Sbjct: 114 --------DLNETALVNPTRFGSLAEYTAADERVLAHKPKNLSFIEAASLPLAIETA-HE 164 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAV-MGCKA-AGAARIIAVDINKDKFAKAKELGATEC 241 + A+++ G + V G G + + K GA+++ A K K + LGA Sbjct: 165 GLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAATASTK-KLDLLRTLGADLA 223 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 301 I+ +E +++ + D ++ +G D ++ E IVG Sbjct: 224 IDYT------KENFEDLPEK-FDVVYDAVGETD---KAVKAVKEGGKVVTIVG------- 266 Query: 302 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 P +L T KG+V + KL + K T PF K+ E F Sbjct: 267 -PATPPAILFVLTSKGSV---------LEKLKPYLESGKVKPVLDPTSPYPFTKVVEAFG 316 Query: 362 LLHSGK-SIRTVL 373 L S + + + V+ Sbjct: 317 YLESSRATGKVVV 329 >2WEK-A nrPDB Length = 341 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 52/274 (18%), Positives = 91/274 (33%), Gaps = 60/274 (21%) Query: 25 EDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVT--PLPVILGHEAAGIVESVG-EGV 81 D V P ++ ++ VG+ +D + +G P +G E G V ++G Sbjct: 23 RDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSAS 82 Query: 82 TTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHF 141 G V + Sbjct: 83 ARYTVGQAVA-------------------------------------------------Y 93 Query: 142 LGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL 201 + +F++YTVV + + + P + + +T Y S + ++ G V Sbjct: 94 MAPGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVTAA 151 Query: 202 -GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 GG G A+ K A +I + +K A K LG IN + +P+ VLK+ Sbjct: 152 AGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLGCDRPINYK--TEPVGTVLKQEYP 208 Query: 261 GGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 GVD +E +G M + G +++G Sbjct: 209 EGVDVVYESVGGA--MFDLAVDALATKGRLIVIG 240 >5A3V-A nrPDB Length = 329 Score = 110 bits (276), Expect = 8e-25, Method: Composition-based stats. Identities = 69/359 (19%), Positives = 109/359 (30%), Gaps = 69/359 (19%) Query: 27 VEVAPPKAYEVRIKMVAVGICRTDDHVVSGN----LVTPLPVILGHEAAGIVESVGEGVT 82 V V PK+ EV +K+ A + D + G L P I + AG V VG GV Sbjct: 26 VPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGVK 85 Query: 83 TVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFL 142 K GDKV+ + + L Sbjct: 86 NFKAGDKVVAVLS---------------------------------------------HL 100 Query: 143 GTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP---GS--TCA 197 G +++ V E K + + T + N A + G Sbjct: 101 GGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANIL 160 Query: 198 VFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 V GGVG AV K A A + A K LGA E + DYK P LK Sbjct: 161 VTAASGGVGHYAVQLAKLANA-HVTAT-CGARNIEFVKSLGADEVL---DYKTPEGAALK 215 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV-IVGVPPASQNLSINPMLLLTGRTW 315 + D + + G + I P A ++ + + + Sbjct: 216 SPSGKKYDAVVHCANGIP--FSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQLV 273 Query: 316 KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK-SIRTVL 373 + ++ E + LV K+ + +I P K + + G + + ++ Sbjct: 274 PLLLIPKAENLEFMVNLV-----KEGKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIV 327 >4EYE-A nrPDB Length = 342 Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats. Identities = 69/376 (18%), Positives = 120/376 (31%), Gaps = 69/376 (18%) Query: 11 KAAVLWEVKKP--FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL--PVIL 66 KA + P DVE V + + A G+C D + G + P + Sbjct: 23 KAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVP 82 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 G E AG+V S EG + +KPGD+V+ Sbjct: 83 GIETAGVVRSAPEG-SGIKPGDRVMA---------------------------------- 107 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 F +++ V + + + + + T Y + Sbjct: 108 --------------FNFIGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYAR 153 Query: 187 VAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 ++ G T V GG+G +A+ K GA ++IAV K +GA + Sbjct: 154 RGQLRAGETVLVLGAAGGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVL--- 209 Query: 246 DYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304 ++ + ++E T G GVD + IG + + G ++VG Sbjct: 210 PLEEGWAKAVREATGGAGVDMVVDPIGGP--AFDDAVRTLASEGRLLVVGFAAGGIPTIK 267 Query: 305 NPMLLLTGRTWKGAVYGGFKSKE-----GIPKLVADFMAKKFSLDALITHVLPFEKINEG 359 LLL + G +G F + +A+ ++ +P + + Sbjct: 268 VNRLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEGM--RPPVSARIPLSEGRQA 325 Query: 360 FDLLHSGK-SIRTVLT 374 GK + VL Sbjct: 326 LQDFADGKVYGKMVLV 341 >2VWH-A nrPDB Length = 357 Score = 100 bits (250), Expect = 8e-22, Method: Composition-based stats. Identities = 73/384 (19%), Positives = 137/384 (35%), Gaps = 50/384 (13%) Query: 11 KAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLP-----VI 65 KA + + + + P++ E ++ + VG+ TD V++G P ++ Sbjct: 2 KAIAVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHG-GFPEGEDHLV 60 Query: 66 LGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 125 LGHEA G+V T ++ GD V+P R + + Y ++ Sbjct: 61 LGHEAVGVVVD--PNDTELEEGDIVVPTVR------RPPASGTNEYFERDQ----PDMAP 108 Query: 126 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASP-----LEKVCLIGCGFSTG 180 DG S++ E + +I + +E + + Sbjct: 109 DGMYFERG------IVGAHGYMSEFFTSPEKYLVRIPRSQAELGFLIEPISITEKALEHA 162 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKA--AGAARIIAV---DINKDKFAKAKE 235 Y ++ + P S+ V G G +GL + K G + + D +E Sbjct: 163 Y-ASRSAFDWDP-SSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEE 220 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 L AT + Q + + +V ++M DF +E G + S+ G ++GV Sbjct: 221 LDATYVDSRQTPVEDVPDVYEQM-----DFIYEATGFPKHAIQSVQALAP-NGVGALLGV 274 Query: 296 PPA-SQNLSINPM---LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVL 351 P + + ++L + G+V + E K+ L+ L+T V Sbjct: 275 PSDWAFEVDAGAFHREMVLHNKALVGSVNSHVEHFEAATVTFTKL--PKWFLEDLVTGVH 332 Query: 352 PFEKINEGFDLLHSGKSIRTVLTF 375 P + FD +I+T + F Sbjct: 333 PLSEFEAAFD--DDDTTIKTAIEF 354 >3WID-A nrPDB Length = 369 Score = 100 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 77/383 (20%), Positives = 133/383 (34%), Gaps = 37/383 (9%) Query: 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLP--- 63 + A V K +++ P+ YE ++K V +GIC TD V+G L Sbjct: 1 MSTINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEG 60 Query: 64 ---VILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120 ++LGHEA V V + +K GD V+PL GKC C+ + C +G+P Sbjct: 61 ENFLVLGHEALLQVLDVSDN-NYIKRGDFVVPLVRRP-GKCVNCRIGRQDNC---SIGDP 115 Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKID-AASPLEKVCLIGCGFST 179 T I+ + V++ + KI PL+ V F Sbjct: 116 DKHEAGITGLHGFMRDVIYDDI-----QNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDV 170 Query: 180 GYGSAVNVAKVTP--GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 ++ + G V G G K G + V+ + + K K + Sbjct: 171 VSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGF-DVTMVNRHDETENKMKMM- 228 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 D+ LK+M D +D + G T+ + G ++ G Sbjct: 229 -------DDFGVGFSNYLKDMPDK-IDLLVDTSGDPSTIFK-FVKKVNNNGVVILFGFNG 279 Query: 298 ASQNLSIN----PMLLLTGRTWKGAV-YGGFKSKEGIPKLVADFMAKKFSLDALITHVLP 352 + +N ++ T G+V + + L + ++ +IT+ Sbjct: 280 KAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAK 339 Query: 353 FEKINEGFDLLHSGKSIRTVLTF 375 E+ N F I+TV+ + Sbjct: 340 PEETNIFFQ--KPKGEIKTVIKW 360 >5LB9-A nrPDB Length = 385 Score = 83.2 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 53/298 (17%), Positives = 96/298 (32%), Gaps = 63/298 (21%) Query: 4 AGKVIKCKAAVLWEVKKPFSIE-----DVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNL 58 +I +A + + +P + +++ EV +K + + +D + + G Sbjct: 19 GRHMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVY 78 Query: 59 VTPL----------PVIL-GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNP 107 + P G+E V VG V++++ GD VIP G R Sbjct: 79 PSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPS-HVNFGTWRTHALG 137 Query: 108 ESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPL 167 + +K L NP + +G + Sbjct: 138 NDDDFIK--LPNPAQSKANGK---------------------------------PNGLTI 162 Query: 168 EKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF--GLGGVGLSAVMGCKAAGAARIIAVDI 225 + I Y + K+TPG + G VG A K I + Sbjct: 163 NQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRD 222 Query: 226 NK---DKFAKAKELGATECI-----NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 + A KELGAT+ I N +++ I+E +K+ + G + +G + Sbjct: 223 RPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQ-SGGEAKLALNCVGGKSS 279 >1V3V-A nrPDB Length = 333 Score = 82.1 bits (201), Expect = 3e-16, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 89/243 (36%), Gaps = 21/243 (8%) Query: 142 LGTSTFSQYTVVD----ENAVAKIDAASPLEKV-CLIGCGFSTGYGSAVNVAKVTPGSTC 196 L S ++ + + D E + + PL IG T Y + V V G T Sbjct: 90 LAQSGWTTHFISDGKGLEKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETV 149 Query: 197 AVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 V G VG K G +++ + +K A K++G N + ++E L Sbjct: 150 LVSAAAGAVGSVVGQIAKLKG-CKVVGAAGSDEKIAYLKQIGFDAAFNYKTV-NSLEEAL 207 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG---VPPASQNLSINP---MLL 309 K+ + G D F+ +G + ++L + G I G V L P ++ Sbjct: 208 KKASPDGYDCYFDNVGGE--FLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESII 265 Query: 310 LTGRTWKGAVYGGFKS---KEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +G + ++ ++ + L+ + K +T FE + F + +G Sbjct: 266 YKQLRIEGFIVYRWQGDVREKALRDLMKWVLEGKIQYHEHVTKG--FENMPAAFIEMLNG 323 Query: 367 KSI 369 ++ Sbjct: 324 ANL 326 >2Y05-A nrPDB Length = 328 Score = 75.9 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 74/226 (32%), Gaps = 17/226 (7%) Query: 155 ENAVAKIDAASPLEKV-CLIGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVGLSAVMGC 212 E + + PL +G T Y + + V G T V G VG Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 161 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 K G +++ + +K A ++LG N + + ++E LK+ + G D F+ +G Sbjct: 162 KLKG-CKVVGAVGSDEKVAYLQKLGFDVVFNYKTV-ESLEETLKKASPDGYDCYFDNVGG 219 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAV---------YGGF 323 +++ + G I G P + + G Sbjct: 220 E--FSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGD 277 Query: 324 KSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSI 369 ++ + L+ + K I FE + F + G ++ Sbjct: 278 ARQKALKDLLKWVLEGKIQYKEYIIEG--FENMPAAFMGMLKGDNL 321 >5GXF-A nrPDB Length = 330 Score = 75.5 bits (184), Expect = 4e-14, Method: Composition-based stats. Identities = 55/265 (20%), Positives = 89/265 (33%), Gaps = 62/265 (23%) Query: 9 KCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVS--GNLVTPLPVIL 66 K +AAV K S+ D+ V EV + + + D + G LV P + Sbjct: 15 KTQAAV-----KQLSLTDLPV-----GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVP 64 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126 G + AG VE+ + KPGDKV+ + E+++ Sbjct: 65 GIDFAGTVENSSDE--RYKPGDKVVLTGW---------RVGEAHW--------------- 98 Query: 127 GTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS--A 184 +SQ V + + + + +G T + A Sbjct: 99 ------------------GGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMA 140 Query: 185 VNVAKVTPGS-TCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 + +TPG V G GGVG A G + AV + LGAT+ + Sbjct: 141 LEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLG-YEVAAVTGRPETADYLTSLGATQIV 199 Query: 243 NPQDYKKPIQEVL-KEMTDGGVDFS 266 + + ++ L E+ G VD Sbjct: 200 ARDEINETVKRPLESEIWAGCVDAV 224 >1O89-A nrPDB Length = 345 Score = 71.3 bits (173), Expect = 7e-13, Method: Composition-based stats. Identities = 55/323 (17%), Positives = 108/323 (33%), Gaps = 61/323 (18%) Query: 23 SIEDVEVAPPKAYEVRIKMVAVGICRTDDHVV--SGNLVTPLPVILGHEAAGIVESVGEG 80 S++ ++ + +V + + + D + G ++ P+I G + AG V + Sbjct: 37 SVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRT--SE 94 Query: 81 VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHH 140 G +V+ T G +H Sbjct: 95 DPRFHAGQEVL---------------------------------------LTGWGVGENH 115 Query: 141 FLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG--SAVNVAKVTP--GSTC 196 + ++ V + + + K +IG T A+ A V P G Sbjct: 116 W---GGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIV 172 Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 GGVG +AV G +++AV + K LGA+ + P+D + + K Sbjct: 173 VTGASGGVGSTAVALLHKLG-YQVVAVSGRESTHEYLKSLGASRVL-PRDEFAESRPLEK 230 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPA-SQNLSINPMLLLTGRT- 314 ++ G + + +G D ++A +L G G+ + ++ P +L R Sbjct: 231 QVWAG----AIDTVG--DKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQ 284 Query: 315 -WKGAVYGGFKSKEGIPKLVADF 336 + + + +LVAD Sbjct: 285 GVDSVMTPPERRAQAWQRLVADL 307 >2J3K-A nrPDB Length = 345 Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 39/179 (21%), Positives = 61/179 (34%), Gaps = 14/179 (7%) Query: 127 GTRRFTCRGKPIHHFL----GTSTFSQYTVVDENAVAKI---DAASPLEKV-CLIGCGFS 178 G R G P + G + +Y+V+ A PL L+G Sbjct: 82 GVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGM 141 Query: 179 TGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK-EL 236 T Y V G T V G VG K G ++ +K+K K + Sbjct: 142 TAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLLKTKF 200 Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 G + N ++ + LK G+D FE +G M+ ++L G + G+ Sbjct: 201 GFDDAFNYKEESD-LTAALKRCFPNGIDIYFENVGG--KMLDAVLVNMNMHGRIAVCGM 256 >2VNA-A nrPDB Length = 357 Score = 58.2 bits (139), Expect = 6e-09, Method: Composition-based stats. Identities = 61/375 (16%), Positives = 120/375 (32%), Gaps = 82/375 (21%) Query: 20 KPFSIEDVEVAP-PKAYEVRIKMVAVGICRTDDHVV-------SGNLVTPLPV--ILGHE 69 + F +E+V + +V+++ + + + D ++ + +TP + ++ Sbjct: 22 ENFRMEEVYLPDNINEGQVQVRTLYLSV---DPYMRCRMNEDTGTDYITPWQLSQVVDGG 78 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTR 129 GI+E T + GD V + P + DG Sbjct: 79 GIGIIEE--SKHTNLTKGDFVTSFYWP----------------------WQTKVILDGNS 114 Query: 130 RFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 + + L Y + IG T Sbjct: 115 LEKVDPQLVDGHLS------YFL------------------GAIGMPGLTSLIGIQEKGH 150 Query: 190 VTPGS--TCAVFGL-GGVGLSAVMGCKAAGAARIIAV-DINKDKFAKAKELGATECINPQ 245 +T GS T V G G G A G +R++ + ++ ELG IN + Sbjct: 151 ITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYK 210 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG-VPPASQNLSI 304 K + E L+E GVD F+ +G + +++ ++ G + ++++ Sbjct: 211 --KDNVAEQLRESCPAGVDVYFDNVGG--NISDTVISQMNENSHIILCGQISQYNKDVPY 266 Query: 305 NPML------LLTGRTWKGAVYGGFKSKE----GIPKLVADFMAKKFSLDALITHVLPFE 354 P L + R + K+ GI +L F K + + + E Sbjct: 267 PPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKETVING--LE 324 Query: 355 KINEGFDLLHSGKSI 369 + F + +G +I Sbjct: 325 NMGAAFQSMMTGGNI 339 >2ZB3-A nrPDB Length = 353 Score = 53.9 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 40/107 (37%), Gaps = 6/107 (5%) Query: 170 VCLIGCGFSTGYGSAVNVAKVTPGS--TCAVFGL-GGVGLSAVMGCKAAGAARIIAV-DI 225 + IG T ++ GS T V G G G A G +R++ + Sbjct: 132 LGAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGT 191 Query: 226 NKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 + ELG +N + + E L+E GGVD F+ +G Sbjct: 192 QEKCLFLTSELGFDAAVNYK--TGNVAEQLREACPGGVDVYFDNVGG 236 >1ZCJ-A nrPDB Length = 463 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVG-LSAVMGCKAAGAARIIAVDINKDKFAKAKEL 236 ST G++ A P S+ V GLG +G A+ + ++AV+ + + AK++ Sbjct: 22 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >3ZWA-A nrPDB Length = 742 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVG-LSAVMGCKAAGAARIIAVDINKDKFAKAKEL 236 ST G++ A P S+ V GLG +G A+ + ++AV+ + + AK++ Sbjct: 301 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >4DIO-A nrPDB Length = 405 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 29/113 (25%), Positives = 43/113 (38%), Gaps = 9/113 (7%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 + A P + V G G GL A+ + GA + A D+ + LGA Sbjct: 177 ALPMMMTAAGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAK 235 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI 292 I +D +E T GG ++ E+ G A+L+ H A VI Sbjct: 236 -FIAVED-----EEFKAAETAGG--YAKEMSGEYQVKQAALVAEHIAKQDIVI 280 >5ILO-A nrPDB Length = 271 Score = 41.6 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 37/109 (33%), Gaps = 13/109 (11%) Query: 193 GSTCAVFG-LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT----------EC 241 G V G GG+GL AAGAA++ +D+ + K A + Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDV 74 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 N + + +E+ K T G +D V G + G Sbjct: 75 ANKKGVEATYEEIAK--TFGNIDIVVNVAGIFNDKDVQRTLLVNLGGII 121 >2EGU-A nrPDB Length = 308 Score = 41.6 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 181 YGSAVNVAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGA 238 +A K+ PG T G G+GL+ V K A ++ ++ ++ + GA Sbjct: 53 IEAAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGA 112 Query: 239 TECINP 244 + P Sbjct: 113 ELVLTP 118 >3MGG-A nrPDB Length = 276 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 42/112 (37%), Gaps = 17/112 (15%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 PG+ G G +G V+ K A I ++DI+ + KA+E ++ K + Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKAREN------TEKNGIKNV 89 Query: 252 QEVLKEM-----TDGGVDFSFEV-----IGRLDTMMASLLCCHEACGTSVIV 293 + + + D D F + + + SL + GT ++ Sbjct: 90 KFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >2VHY-A nrPDB Length = 377 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 42/151 (27%), Gaps = 16/151 (10%) Query: 161 IDAASPLEKVCLIGCGFSTGYGSAVNVAK----------VTPGSTCAVFGLGGVGLSAVM 210 + +P+ +V Y V P V G G G +A Sbjct: 127 LPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPAD-VVVIGAGTAGYNAAR 185 Query: 211 GCKAAGAARIIAVDINKDKFAK--AKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE 268 GA + +DIN DK + A+ G Y+ ++ G V Sbjct: 186 IANGMGA-TVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAV--LVP 242 Query: 269 VIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299 + SL+ + V + + Sbjct: 243 GAKAPKLVSNSLVAHMKPGAVLVDIAIDQGG 273 >1XLT-A nrPDB Length = 384 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 + + A P + VFG+G GL A+ K GA ++A D+ + + LG Sbjct: 159 AFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLG 215 >1X14-A nrPDB Length = 401 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 35/89 (39%), Gaps = 2/89 (2%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 + + A P + V G G GL+A+ + GA + A D + + + +GA Sbjct: 160 FTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGAEF 218 Query: 241 C-INPQDYKKPIQEVLKEMTDGGVDFSFE 268 ++ ++ K M+D + E Sbjct: 219 LELDFKEEAGSGDGYAKVMSDAFIKAEME 247 >2B25-A nrPDB Length = 336 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 43/117 (36%), Gaps = 14/117 (11%) Query: 189 KVTPGSTCAVFGLGGVGLSAVMGCKAAGA-ARIIAVDINKDKFAKAKELGATE-----CI 242 + PG T G G G ++ KA G+ R+I+ ++ KD AK+ Sbjct: 102 DINPGDTVLEAGSG-SGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLS 160 Query: 243 NPQDYKKPIQEVLKEMTDGGVDF---SFEVIG----RLDTMMASLLCCHEACGTSVI 292 + +++ + + K+++ D +F+ + + + G + Sbjct: 161 HVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLKHGGVCAV 217 >3X2F-A nrPDB Length = 411 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 45/148 (30%), Gaps = 14/148 (9%) Query: 174 GCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKA 233 G G ST N + G V G G G + GA R+I +++ K Sbjct: 178 GTGQSTWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVK---- 232 Query: 234 KELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 A E I P++E +K DF G D + + + Sbjct: 233 ----AVEAIMDGFTVMPMKEAVKI-----ADFVITASGNTDVLSKEDILSLKDGAVLANA 283 Query: 294 GVPPASQNLSINPMLLLTGRTWKGAVYG 321 G + + + + + V G Sbjct: 284 GHFNVEIPVRVLEEIAVEKFEARPNVTG 311 >6BII-A nrPDB Length = 333 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 29/78 (37%), Gaps = 10/78 (12%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 + + + G T + G G +G + K G I K KELGA Sbjct: 137 AWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMR--ILYTARSRKPEAEKELGAE 194 Query: 240 ECINPQDYKKPIQEVLKE 257 KP++E+L+E Sbjct: 195 F--------KPLEELLRE 204 >5JE5-A nrPDB Length = 247 Score = 37.0 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 49/139 (35%), Gaps = 25/139 (17%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G + GAA+++ VDI++ A+E + Y P++ Sbjct: 42 GKSVLDLACG-FGFFGREIYR-RGAAKVVGVDISEKMIELARE-------ESRKYGDPLE 92 Query: 253 EVLKEMTD----GGVDFS--------FEVIGRLDTMMASLLCCHEACGTSVIVGVPP--- 297 ++++ + G D + + L M + + G V V P Sbjct: 93 FHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPDFS 152 Query: 298 -ASQNLSINPMLLLTGRTW 315 A N + + +L R W Sbjct: 153 LAKGNFAKYGVNVLNERAW 171 >5EKU-A nrPDB Length = 390 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 44/124 (35%), Gaps = 6/124 (4%) Query: 115 NDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV---DENAVAKIDAASPLEKVC 171 N L N G + G + G V V+ I+A + Sbjct: 16 NALQNTIGFVPPGATLASVSGYRPPDAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAM 75 Query: 172 LIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFA 231 + + Y + VTP + G G GL ++M K GA ++AV+ +++ Sbjct: 76 MNDEERNNFYYEVLKK-HVTPETGVLEIGAG-SGLLSLMAAK-LGAKWVVAVEGSEELAK 132 Query: 232 KAKE 235 A+E Sbjct: 133 LARE 136 >1VH3-A nrPDB Length = 262 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 216 GAARIIAVDINKDKFAKAKELGATEC---INPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 GA+R+I N++ AK GA C +N + + EV++++ + + G Sbjct: 41 GASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLAEVVEKLAIPDNEIIVNIQGD 100 Query: 273 LDTM 276 + Sbjct: 101 EPLI 104 >1V8B-A nrPDB Length = 479 Score = 36.2 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 38/124 (30%), Gaps = 16/124 (12%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G VG K GA R+ +I+ +A G Sbjct: 257 GKIVVICGYGDVGKGCASSMKGLGA-RVYITEIDPICAIQAVMEGFNVV----------- 304 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTG 312 L E+ D G DF G +D + L + +G + +N + G Sbjct: 305 -TLDEIVDKG-DFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHF--DDEIQVNELFNYKG 360 Query: 313 RTWK 316 + Sbjct: 361 IHIE 364 >4XIJ-A nrPDB Length = 275 Score = 36.2 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK----FAKAKELGA 238 V A T G + V G GG +AV+ G RI V ++ K A+ GA Sbjct: 117 GVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARRCGA 175 >4M36-A nrPDB Length = 343 Score = 36.2 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 189 KVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 VTP + G G GL ++M K GA ++AV+ +++ A+E Sbjct: 57 HVTPETGVLEIGAG-SGLLSLMAAK-LGAKWVVAVEGSEELAKLARE 101 >1BW9-B nrPDB Length = 356 Score = 36.2 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G T V GLG VG S AGA +++ D + ++ A A LG T P Sbjct: 176 GLTVLVQGLGAVGGSLASLAAEAGA-QLLVADTDTERVAHAVALGHTAVALEDVLSTPCD 234 Query: 253 EVLKEMTDGGV 263 V GGV Sbjct: 235 -VFAPCAMGGV 244 >2YVG-A nrPDB Length = 408 Score = 36.2 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 45/137 (32%), Gaps = 17/137 (12%) Query: 162 DAASPLEKVCLIGCGFSTGYGSAVN-VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARI 220 A P + + A A + P S + G G +GL + AG + Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGV-HV 171 Query: 221 IAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE--VIGRLDTMMA 278 V+ ++A A + V + GVD FE V G +D ++ Sbjct: 172 SLVETQPRLMSRA----APATL--------ADFVARYHAAQGVDLRFERSVTGSVDGVVL 219 Query: 279 SLLCCHEACGTSVIVGV 295 L V+VG+ Sbjct: 220 -LDDGTRIAADMVVVGI 235 >5X7F-A nrPDB Length = 235 Score = 36.2 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 11/134 (8%) Query: 168 EKVCLIGCGFSTGYGSA--VNVAKVTPGSTCAVFG--LGGVGLSAVMGCKAAGAARIIAV 223 E+ IG G T A +AK++ G A G G GL + G + G I Sbjct: 52 ERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTI-- 109 Query: 224 DINKDKFAKAKELGATECINPQDYK---KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL 280 DI + A++ A I P + QEVL + D D F +D Sbjct: 110 DIEPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDADPIDQPDYVA 169 Query: 281 LCC--HEACGTSVI 292 + G V+ Sbjct: 170 EGVRLLRSGGVIVV 183 >3VPX-A nrPDB Length = 364 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKA-KELGATEC 241 G T AV G+G V + GA ++I DIN++ +A GAT Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGA-KLIITDINEEAVQRAVDAFGATAV 221 >6BQC-A nrPDB Length = 383 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 51/128 (39%), Gaps = 10/128 (7%) Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKEL--GATECI 242 ++ PG G G GL+ M ++ V I+ ++ A+E G I Sbjct: 161 CEKLQLKPGMRVLDIGCGWGGLAHYMASNY--DVSVVGVTISAEQQKMAQERCEGLDVTI 218 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIG--RLDTMMASLLCCHEACGTSVIVGVPPASQ 300 QDY+ + + ++ G FE +G DT A + + G ++ + Sbjct: 219 LLQDYRDLNDQFDRIVSVG----MFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKT 274 Query: 301 NLSINPML 308 +L+++P + Sbjct: 275 DLNVDPWI 282 >6ACF-A nrPDB Length = 367 Score = 35.1 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAG--AARIIAVDINKDKFAKA-KELGATECINPQDYKK 249 G AV G VG A C+ A++I DINK+ A+A +E GA ++P D Sbjct: 173 GKVVAVQG---VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAK-AVDPNDIYG 228 Query: 250 PIQEVLKEMTDGGV 263 ++ GG+ Sbjct: 229 VECDIFAPCALGGI 242 >5Z1Z-A nrPDB Length = 329 Score = 35.1 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T V G G +G++ + K G R++A D A A ELG Sbjct: 144 GKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYV 189 >1V9L-A nrPDB Length = 421 Score = 35.1 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 1/59 (1%) Query: 168 EKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDIN 226 E G +T A + G T A+ G+G VG + GA I DIN Sbjct: 186 EYATGFGVAVATR-EMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDIN 243 >4K2X-A nrPDB Length = 523 Score = 35.1 bits (79), Expect = 0.048, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 5/72 (6%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT----ECINPQDYKKPI 251 + G G GL + AGA R + ++ + +K LG E ++ + + Sbjct: 25 VVIAGAGPTGLMLACELRLAGA-RTLVLERLAEPVDFSKALGVHARTVELLDMRGLGEGF 83 Query: 252 QEVLKEMTDGGV 263 Q ++ G Sbjct: 84 QAEAPKLRGGNF 95 >6IQV-A nrPDB Length = 340 Score = 35.1 bits (79), Expect = 0.049, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 44/129 (34%), Gaps = 24/129 (18%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAA----RIIAVD--INKDKFAKAKELGATE-------- 240 + G G +G A G ++A++ + A + +T Sbjct: 4 KIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVS 63 Query: 241 ------CINPQDYK---KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV 291 +N ++Y+ +P + + + + GVDF E G T A +A V Sbjct: 64 ATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTG-FYTSKAKSQAHLDAGAKRV 122 Query: 292 IVGVPPASQ 300 ++ P S Sbjct: 123 LISAPAGSD 131 >4FS8-A nrPDB Length = 383 Score = 34.7 bits (78), Expect = 0.066, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 61/177 (34%), Gaps = 21/177 (11%) Query: 104 CKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDA 163 C + C K+ G +++D + + L TS V E+ + Sbjct: 5 CASG----CQKSKNGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILAD 60 Query: 164 ASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA-ARIIA 222 + GCG + ++ G+T G G G + K G ++I Sbjct: 61 IADEVLEKFYGCGSTLPADGSLE------GATVLDLGCGT-GRDVYLASKLVGEHGKVIG 113 Query: 223 VDINKDKFAKAKE---------LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 VD+ ++ A++ G+ N + K I+ + +G D S +++ Sbjct: 114 VDMLDNQLEVARKYVEYHAEKFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIV 170 >6C55-A nrPDB Length = 340 Score = 34.7 bits (78), Expect = 0.067, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 27/80 (33%), Gaps = 9/80 (11%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKEL 236 +T Y G AV G G G + K G +I + + F KAKE Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRS-FDKAKED 59 Query: 237 GATECINPQDYKKPIQEVLK 256 G P+ E +K Sbjct: 60 GFDVF--------PVAEAVK 71 >5VMT-A nrPDB Length = 342 Score = 34.7 bits (78), Expect = 0.073, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 43/129 (33%), Gaps = 21/129 (16%) Query: 195 TCAVFGLGGVGLSAV-MGCKAAGAARIIAV---------------DINKDKFAKAKELGA 238 A+ G G +G A+ KA G + AV D + +F EL Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGI-EVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKD 70 Query: 239 TE-CINPQDYKKPIQEVLKEMTDG--GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 +N ++ K +E+ G GVD E G T A V++ Sbjct: 71 DAIVVNGREIKVFANPNPEELPWGELGVDVVLECTG-FFTNKTKAEAHIRAGARKVVISA 129 Query: 296 PPASQNLSI 304 P + ++ Sbjct: 130 PGGNDVKTV 138 >4CUK-A nrPDB Length = 338 Score = 34.3 bits (77), Expect = 0.093, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T V G G +G++A+ K G R++A D A +LG Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPST--AALDLGVEYV 189 >1W1U-A nrPDB Length = 557 Score = 34.3 bits (77), Expect = 0.099, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 35/97 (36%), Gaps = 7/97 (7%) Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + G GLGG+G + + AGA + ++ + + E T ++ Q Sbjct: 160 HYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACS-LNIESQQSRIDFRLE---TRYVDEQ 215 Query: 246 --DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL 280 D + + K T G S + G ++ L Sbjct: 216 ATDLDDALVRIAK-YTAEGKAISIALHGNAAEILPEL 251 >2O23-A nrPDB Length = 265 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY--KKPIQE 253 G G+GL+ GA+ ++ N A+AK+LG P D +K +Q Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 254 VLKEMTD--GGVDFSFEVIGRLDTMMA 278 L G VD + G Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVASKT 102 >1EUF-A nrPDB Length = 227 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 41/96 (42%), Gaps = 9/96 (9%) Query: 111 YCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPL-EK 169 +CL + + G R T + P+ + ++ T+ ++ + K+ + + +K Sbjct: 44 HCLGSSINVTLGAHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDK 103 Query: 170 VCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVG 205 V I ++A+V PG C+V G G +G Sbjct: 104 VSPINLP--------RSLAEVKPGMMCSVAGWGRLG 131 >1DXY-A nrPDB Length = 333 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 20/53 (37%), Gaps = 2/53 (3%) Query: 181 YGSAVNVAKVTPGS-TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAK 232 Y A G T V G G +G A+ K GA ++IA D K Sbjct: 132 YEKAGTFIGKELGQQTVGVMGTGHIGQVAIKLFKGFGA-KVIAYDPYPMKGDH 183 >1I9G-A nrPDB Length = 280 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 32/180 (17%), Positives = 60/180 (33%), Gaps = 11/180 (6%) Query: 124 LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 L G T RG H + A+ + ++ V + G Y Sbjct: 27 LTPGAEFHTHRGSIAHDAVIGLEQGSVVKSSNGALFLVLRPLLVDYVMSMPRGPQVIYPK 86 Query: 184 ----AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAG-AARIIAVDINKDKFAKAKEL-- 236 V+ + PG+ G G G + +A G A ++I+ + D A+ Sbjct: 87 DAAQIVHEGDIFPGARVLEAGAG-SGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVS 145 Query: 237 GATECINPQDYKKPIQEVL-KEMTDGGVD-FSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 G P +++ + ++ E+ DG VD +++ + + A V V Sbjct: 146 GC-YGQPPDNWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMVYVA 204 >4N7R-A nrPDB Length = 472 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 173 IGCGFSTGYGSAVNVAKVTPGST------CAVFGLGGVGLSAVMGCKAAGAARIIAVDIN 226 I G + +AV +A + + V G G +G + A G +++ V+ + Sbjct: 181 IASGAVSVSSAAVELALMKLPQSSNVSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRS 240 Query: 227 KDKFAKAKE 235 +++ + +E Sbjct: 241 EERVSAIRE 249 >3D2L-A nrPDB Length = 243 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 23/52 (44%), Gaps = 4/52 (7%) Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 A + +V PG A G G G + ++ + VD++++ A+E Sbjct: 25 AWVLEQVEPGKRIADIGCGT-GTATLLLADHY---EVTGVDLSEEMLEIAQE 72 >1JWB-B nrPDB Length = 249 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDIN 226 S + GLGG+G +A +AG + +D + Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >4COO-A nrPDB Length = 563 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 152 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 211 Query: 242 INPQDYK 248 P + + Sbjct: 212 RTPTNAR 218 >1M54-A nrPDB Length = 363 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 87 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 146 Query: 242 INPQDYK 248 P + + Sbjct: 147 RTPTNAR 153 >3EGI-A nrPDB Length = 206 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK 234 V GVG + + R+IA+DI+ K A A+ Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 82 >3GDH-A nrPDB Length = 241 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK 234 V GVG + + R+IA+DI+ K A A+ Sbjct: 81 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 117 >5JXW-A nrPDB Length = 498 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 33/103 (32%), Gaps = 14/103 (13%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG G GA R+I +I+ +A G + + Sbjct: 270 AGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEIDPICALQASMEGYQVSV--------L 320 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 ++V+ E D G D + + + +G Sbjct: 321 EDVVSE-----ADIFITATGNKDVITVEHMRKMKENAYIANIG 358 >5F8E-A nrPDB Length = 377 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 48/117 (41%), Gaps = 10/117 (8%) Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYK 248 + G+ A FG G G + + +A GA+R +D + + A E A + N + Sbjct: 185 LRSGADVADFGCG-SGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFER 243 Query: 249 KPIQEVLKEMTDGGVDF--SFEVI---GRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 + E+ K G D F+ I + ++ ++ G ++V + +SQ Sbjct: 244 HDLAELDKV---GAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQ 297 >5MMS-A nrPDB Length = 408 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 130 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 189 Query: 242 INPQDYK 248 P + + Sbjct: 190 RTPTNAR 196 >2EEZ-A nrPDB Length = 369 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 36/115 (31%), Gaps = 1/115 (0%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + + G G VG +A GA ++ +D+N + ++ I + I++ Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 255 LKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLL 309 ++ + +L + V V V +I P Sbjct: 227 VQHADLLIGAVLVPGAKAPKLVTRDMLSLMKEGAVIVDVAVDQGGCVETIRPTTH 281 >2ZJ1-A nrPDB Length = 495 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 31/102 (30%), Gaps = 14/102 (13%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G VG K GA R+ +I+ +A G ++ Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVV--------TVE 325 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 E + G D G D +M + + +G Sbjct: 326 EAI-----GDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG 362 >1E3W-A nrPDB Length = 261 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 6/88 (6%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 G G+GLS GA ++ N + +AK+LG P + +EV Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE-KEVQ 72 Query: 256 KEMTD-----GGVDFSFEVIGRLDTMMA 278 +T G +D + G + Sbjct: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKT 100 >2EKL-A nrPDB Length = 313 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T + G G +G + A G +++A DI + KA+++ A Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGM-KVLAYDILDIR-EKAEKINAKAV 188 >5JJC-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 3/70 (4%) Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAV--DINKDKFAKAKELGATEC 241 A + PG G G+ M KA G I + +++K + LGA Sbjct: 53 AEKRGLLRPGGVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELI 112 Query: 242 -INPQDYKKP 250 + Y+ P Sbjct: 113 EVPAAPYRNP 122 >5AOV-A nrPDB Length = 336 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 25/65 (38%), Gaps = 10/65 (15%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G T + G G +G + K I K KELGA +P++ Sbjct: 150 GKTIGIVGFGRIGQAIARRAKGFNMR--ILYYSRTRKSQAEKELGAEY--------RPLE 199 Query: 253 EVLKE 257 EVLKE Sbjct: 200 EVLKE 204 >4WJI-A nrPDB Length = 293 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 41/132 (31%), Gaps = 13/132 (9%) Query: 194 STCAVFGLGGVGLSAVMGCK-AAGAARIIAVDINKDKFAKAKE--LGATECINPQDYKKP 250 T A+ G+G +G S + A I+ ++ +A E LG ++ + + Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELGLGDRYTLSAAEAVEG 64 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 310 V+ + +G + A + + VG S + P L Sbjct: 65 ADLVVVSVP----------VGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPK 114 Query: 311 TGRTWKGAVYGG 322 G G Sbjct: 115 DVHFVPGHPIAG 126 >1CYD-A nrPDB Length = 244 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 193 GSTCAVFGLG-GVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 G V G G G+G V A+GA + N D + AKE Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKE 50 >4AEC-A nrPDB Length = 430 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 31/85 (36%), Gaps = 8/85 (9%) Query: 184 AVNVAKVTPGSTCAV---FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 A ++PG + V G G+GL+ + + + ++ ++ K GA Sbjct: 165 AEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAEL 224 Query: 241 CIN-----PQDYKKPIQEVLKEMTD 260 + + +E+LK D Sbjct: 225 VLTDPAKGMTGAVQKAEEILKNTPD 249 >4GCM-A nrPDB Length = 312 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 38/224 (16%), Positives = 63/224 (28%), Gaps = 57/224 (25%) Query: 196 CAVFGLGGVGLSAVMGCKAA--------------------------GAARIIAVDINKDK 229 A+ G G G++A + A G I D++ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKM 68 Query: 230 FAKAKELGATE---------------CINPQDYKKPIQEVL----KEMTDGGVDFSFEVI 270 F AK+ GA IN + + + V+ E GV E+ Sbjct: 69 FEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELG 128 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIP 330 GR + A ++G ++ T + + Sbjct: 129 GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIV-----HRRDELRAQ 183 Query: 331 KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLT 374 +++ D K +D + +H L INE GK LT Sbjct: 184 RILQDRAFKNDKIDFIWSHTLK--SINE-----KDGKVGSVTLT 220 >3KYD-B nrPDB Length = 551 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%) Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDIN 226 G +A+ G V G GG+G + G + I +D++ Sbjct: 8 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >3KYC-B nrPDB Length = 660 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%) Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDIN 226 G +A+ G V G GG+G + G + I +D++ Sbjct: 26 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >2ISQ-A nrPDB Length = 320 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 31/99 (31%), Gaps = 8/99 (8%) Query: 184 AVNVAKVTPGSTCAV---FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 A + PG + + G GVGL+ K + ++ ++ G Sbjct: 55 AEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVEL 114 Query: 241 CIN-----PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLD 274 + + +E+L + +G + FE Sbjct: 115 VLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPK 153 >5D84-A nrPDB Length = 326 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 24/72 (33%), Gaps = 6/72 (8%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVD--INKDKFAKAKELGA 238 + +T + G +G++ M K G VD I+ K GA Sbjct: 55 IEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGA 114 Query: 239 TECINPQDYKKP 250 N + ++P Sbjct: 115 ----NVEMVEEP 122 >4OM8-A nrPDB Length = 309 Score = 32.8 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 43/120 (35%), Gaps = 13/120 (10%) Query: 195 TCAVFGLGGVG-LSAVMGCKAAGAARIIAVDINKDKFAKAKEL--GATECINPQDYKKPI 251 A+ GLG +G A + G +++A D+ +A+ + A ++ P Sbjct: 4 NIAIIGLGTMGPGMAARLAR--GGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 252 QEV--LKEMTD-----GGVDFSFEVIGRLDTMMASLLCCHEAC-GTSVIVGVPPASQNLS 303 V ++ D G D E + ++ A + + G IV + ++ Sbjct: 62 AGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPIT 121 >6FZI-A nrPDB Length = 332 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 23/125 (18%), Positives = 40/125 (32%), Gaps = 21/125 (16%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAV-DINKDK-FAKAKEL---------------G 237 A+ G G +G A+ ++A+ D+ K A + G Sbjct: 3 KVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEG 62 Query: 238 ATECINPQDYKKPIQEVLKEMTDG--GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 A +N ++ K + E+ G GVD E G + A V++ Sbjct: 63 A-FVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFAS-KEKASAHLTAGAKKVVISA 120 Query: 296 PPASQ 300 P + Sbjct: 121 PAGND 125 >4DIB-A nrPDB Length = 345 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 46/134 (34%), Gaps = 31/134 (23%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAV---------------DINKDKFAKAKELGAT 239 A+ G G +G A I+A+ D KF E Sbjct: 6 RVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFED 65 Query: 240 E---------CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 +N +D K+ TD GV+ E G+ ++ ++L EA Sbjct: 66 HLLVDGKMIRLLNNRDPKELPW------TDLGVEVVIEATGKFNSKEKAIL-HVEAGAKK 118 Query: 291 VIVGVPPASQNLSI 304 VI+ P +++++I Sbjct: 119 VILTAPGKNEDVTI 132 >3G1U-A nrPDB Length = 437 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINK 227 G TC V G G VG +A GA R++ +++ Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP 245 >5U9P-A nrPDB Length = 265 Score = 32.4 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 34/90 (37%), Gaps = 14/90 (15%) Query: 193 GSTCAVFGLG-GVGLSAVMGCKAAGAARIIAVDINKDKFA-KAKE-----LGATECI--- 242 G + G G G+GL+ G AGAA +I D N++K A A+ A + Sbjct: 20 GRRALITGSGRGIGLTLARGLAEAGAAIVIN-DRNEEKAATLARRFRDEGFAADHAVFDV 78 Query: 243 -NPQDYKKPIQEVLKEMTDGGVDFSFEVIG 271 + I E + G +D G Sbjct: 79 AEHAQVRAAIDEFEARV--GAIDILVNNAG 106 >3JTJ-A nrPDB Length = 253 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 41/126 (32%), Gaps = 8/126 (6%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK--- 248 PG A + + + A+GA R+I + D + G C+ D++ Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDT-----MMASLLCCHEACGTSVIVGVPPASQNLS 303 + + EV++ D V G + + VP AS + Sbjct: 80 ERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEA 139 Query: 304 INPMLL 309 NP + Sbjct: 140 FNPNAV 145 >3ZZN-A nrPDB Length = 310 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 27/173 (15%), Positives = 49/173 (28%), Gaps = 15/173 (8%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + G G VG + G AR + + K A+A A + ++ + P+ Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAH---AEDILHATPFAHPVWVW 58 Query: 255 LKEMTD-GGVDFSFEVIGRLDTMMASLLCCHEACGTS-------VIVGVPPASQNLSINP 306 D G G + L + V+ P A ++ NP Sbjct: 59 AGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNP 118 Query: 307 MLLLTGR--TWKGAVYGGFKSKEGIPKLV--ADFMAKKFSLDALITHVLPFEK 355 + ++T G G I +A+ + H + Sbjct: 119 VDVMTQVAYALSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGE 171 >1ZFN-A nrPDB Length = 253 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFA 231 S + GLGG+G A + AG ++ D + + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLS 68 >4XGI-A nrPDB Length = 436 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 19/48 (39%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVD 224 F G +A G+ AV G G VG A + AGA I D Sbjct: 215 FVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQD 262 >2HMT-A nrPDB Length = 144 Score = 32.0 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S V G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGH-EVLAVDINEEKVNAYASYATHAVIANATEENE--- 62 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 63 --LLSLGIRNFEYVIVAIGA 80 >5BUT-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S V G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGH-EVLAVDINEEKVNAYASYATHAVIANATEENE--- 62 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 63 --LLSLGIRNFEYVIVAIGA 80 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S V G ++AVDIN++K I N + + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGH-EVLAVDINEEKVNAYASYATHAVIANATEENE--- 204 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 205 --LLSLGIRNFEYVIVAIGA 222 >1NVM-B nrPDB Length = 312 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 36/102 (35%), Gaps = 10/102 (9%) Query: 195 TCAVFGLGGVG--LS--AVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 A+ G G +G L + K ++ +D D A+A+ +G T Sbjct: 6 KVAIIGSGNIGTDLMIKVLRNAKYLEMGAMVGIDAASDGLARAQRMGVTTTY------AG 59 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI 292 ++ ++K +DF F+ + L G +I Sbjct: 60 VEGLIKLPEFADIDFVFDATSASAHVQNEALLRQAKPGIRLI 101 >5TQV-A nrPDB Length = 233 Score = 31.6 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 194 STCAVFGLG-GVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT-ECINPQDYKKPI 251 T + G G+G V + G +IA + A + LGA ++ + I Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGW-NVIATARDDASLAALRALGAHAHALDITQP-EQI 67 Query: 252 QEVLKEMTDGGVDFSFEVIGR 272 + ++ +D + V G Sbjct: 68 AALGWKLDGERLDVAVVVSGV 88 >1GPJ-A nrPDB Length = 404 Score = 31.6 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 26/65 (40%), Gaps = 5/65 (7%) Query: 182 GSAVNVAKVTPGS----TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK-FAKAKEL 236 +AV +A+ GS T V G G +G + G ++ + ++ A++L Sbjct: 152 SAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDL 211 Query: 237 GATEC 241 G Sbjct: 212 GGEAV 216 >5VJ7-A nrPDB Length = 476 Score = 31.6 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 46/122 (37%), Gaps = 11/122 (9%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G A+ G G GL+ G I + + G E P++ ++ Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL--HQPGGVLTYGIPEFRLPKEI---LR 208 Query: 253 EVLKEMTDGGVDFSFE-VIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLT 311 + LK+++ GV+ + ++G+ T+ L +V +G + L P + L Sbjct: 209 KELKKLSLLGVEIKTDHIVGKTITIQELLQEY-----DAVFIGTGAGTPKLPNIPGINLN 263 Query: 312 GR 313 G Sbjct: 264 GI 265 >1XDW-A nrPDB Length = 331 Score = 31.6 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 24/65 (36%), Gaps = 3/65 (4%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPIQ 252 T V GLG +G A GA +I D+ + K ++ E + D Sbjct: 148 TVGVVGLGRIGRVAAQIFHGMGA-TVIGEDVFEIKGIEDYCTQVSLDEVLEKSDIITIHA 206 Query: 253 EVLKE 257 +KE Sbjct: 207 PYIKE 211 >3AOE-A nrPDB Length = 424 Score = 31.2 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 19/48 (39%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVD 224 F T +A + G+ A+ G G VG +A GA + D Sbjct: 203 FITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQD 250 >3EMK-A nrPDB Length = 246 Score = 31.2 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 30/86 (34%), Gaps = 9/86 (10%) Query: 193 GSTCAVFGL-GGVGLSAVMGCKAAGAARIIAV-DINKDKF-AKAKELGATECINPQDYKK 249 G V G GG+G + A GA I+ + ++K A ELG + P + Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGA--IVGLHGTREEKLKELAAELGERIFVFPANLSD 64 Query: 250 PIQ----EVLKEMTDGGVDFSFEVIG 271 E GGVD G Sbjct: 65 REAVKALGQKAEEEMGGVDILVNNAG 90 >4K28-A nrPDB Length = 269 Score = 31.2 bits (69), Expect = 0.69, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 18/49 (36%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK 229 G+A G V G GGVG + AG A I D + + Sbjct: 113 LGAAHKHGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTAR 161 >3TNL-A nrPDB Length = 315 Score = 31.2 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 34/90 (37%), Gaps = 10/90 (11%) Query: 179 TGYGSAVNVAK-VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 TGY A+ A G + G GG + + G I + D +A A++ Sbjct: 139 TGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEK-- 196 Query: 238 ATECINPQD-------YKKPIQEVLKEMTD 260 E IN + + +++ KE+ + Sbjct: 197 TVEKINSKTDCKAQLFDIEDHEQLRKEIAE 226 >4J90-A nrPDB Length = 222 Score = 31.2 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 28/80 (35%), Gaps = 7/80 (8%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQ 252 AV GLG G S G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSICKELHRMGH-EVLAVDINEEKVNAYASYATHAVIANATEENE--- 62 Query: 253 EVLKEMTDGGVDFSFEVIGR 272 L + ++ IG Sbjct: 63 --LLSLGIRNFEYVIVAIGA 80 >3BKX-A nrPDB Length = 275 Score = 31.2 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 178 STGYGSAV-NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDI 225 T + A+ +V PG G G LSAV+ + + + +DI Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDI 76 >3FBT-A nrPDB Length = 282 Score = 31.2 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 3/84 (3%) Query: 180 GYGSAVNVAKVT-PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGA 238 G+G ++ +V + C V G GG + + K A I V N +K ++ G Sbjct: 108 GFGKMLSKFRVEIKNNICVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEK--TSEIYGE 165 Query: 239 TECINPQDYKKPIQEVLKEMTDGG 262 + I+ + +V+ T G Sbjct: 166 FKVISYDELSNLKGDVIINCTPKG 189 >4YRY-B nrPDB Length = 468 Score = 31.2 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 41/136 (30%), Gaps = 12/136 (8%) Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 + G AV G G + A GA ++ V ++ A+ + Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFL 335 Query: 250 PIQEVLKEMTDGGVDF-SFEVI----------GRLDTM-MASLLCCHEACGTSVIVGVPP 297 + ++ + D + + E + GR + + E +G P Sbjct: 336 WLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGP 395 Query: 298 ASQNLSINPMLLLTGR 313 LS P L L R Sbjct: 396 NRVLLSEFPGLELNER 411 >3F9I-A nrPDB Length = 249 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 5/46 (10%) Query: 193 GSTCAVFGLG-GVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 G T + G G+G + G +++I N++K K LG Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLG-SKVIISGSNEEKL---KSLG 55 >4PZE-A nrPDB Length = 284 Score = 31.2 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 15/38 (39%), Gaps = 1/38 (2%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAK 232 T + G G +G C G ++ VDI+ K Sbjct: 5 TVGIVGAGTMGNGIAQACAVVG-LNVVMVDISDAAVQK 41 >5OHX-A nrPDB Length = 504 Score = 31.2 bits (69), Expect = 0.84, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 27/69 (39%), Gaps = 6/69 (8%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGAARIIAV--DINKDKFAKAKELGAT 239 A + + PG T G G+GL+ M G II + ++ +K + LGA Sbjct: 89 AEDKGLLKPGCTIIEPTSGNTGIGLA--MAAAVRGYKCIIVMPEKMSDEKISTLYALGAK 146 Query: 240 ECINPQDYK 248 P + Sbjct: 147 IIRTPTEAS 155 >6J0Z-C nrPDB Length = 491 Score = 30.8 bits (68), Expect = 0.86, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 S V G G GL + AG + ++ +D + +++ LG Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG 48 >3HM2-A nrPDB Length = 178 Score = 30.8 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 13/102 (12%), Positives = 32/102 (31%), Gaps = 1/102 (0%) Query: 202 GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 GG G A+ ++ + +I++++ + ++ + + + Sbjct: 34 GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAFDDVPD 93 Query: 262 GVDFSFEVIG-RLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 D F G + A+ G V V S+ + Sbjct: 94 NPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQM 135 >1QO8-A nrPDB Length = 566 Score = 30.8 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINK 227 A + + V G G G +A + K AGA +I VD Sbjct: 115 AAGPSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAP 154 >4RS3-A nrPDB Length = 327 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 21/86 (24%) Query: 204 VGLSAVMGCKAAG--AARIIAVDINKDKFAKAKE---LG----------------ATECI 242 +GL A+ K AG I+ +D +D K +G A + Sbjct: 205 MGLGALQALKEAGRTGVPIVGIDGIEDGLNAVKSGDFIGTSLQNGTVELSAGLAVADALV 264 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFE 268 +D K V+ +T VD + E Sbjct: 265 KGEDVKTDPVYVMPAITKDNVDVAIE 290 >1VE9-A nrPDB Length = 347 Score = 30.8 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 E +E+ GG D G ++ G + V P Sbjct: 165 ESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAP 208 >6DLL-A nrPDB Length = 398 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 10/27 (37%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARIIA 222 A+ G G GL AG II Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIV 34 >3GDF-A nrPDB Length = 267 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 46/132 (34%), Gaps = 14/132 (10%) Query: 179 TGYGSAVNVAKVTPGSTCAVFGLG---GVGLSAVMGCKAAGAARIIAVDINKD-KFAKAK 234 T + S ++ + G V G G+G+ A GC GAA I K Sbjct: 7 TKHESLLDQLSLK-GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVK 65 Query: 235 ELGATECINPQDYK------KPIQEVLKEMTD--GGVDFSFEVIGRLDTMMASLLCCHEA 286 EL T I + YK + ++++K++ G +D G L EA Sbjct: 66 ELEKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATAD-SGILDGSVEA 124 Query: 287 CGTSVIVGVPPA 298 V V + Sbjct: 125 WNHVVQVDLNGT 136 >2HAE-A nrPDB Length = 386 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 58/195 (29%), Gaps = 43/195 (22%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDI------------------------NKDK- 229 V G+G G + V G ++AVD N ++ Sbjct: 184 KVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNENDPETCLNEYHLEIARITNPERL 243 Query: 230 ---FAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEA 286 A E GA I E +K+M+ V F+ + + Sbjct: 244 SGDLETALE-GADFFIGVSRGNILKPEWIKKMSRKPVIFAL------ANPVPEIDPELAR 296 Query: 287 CGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDAL 346 + IV + +N +L G KGAV K + + + +A+ + Sbjct: 297 EAGAFIVATGRSDHPNQVNNLLAFPGI-MKGAVEKRSKITKNMLLSAVEAIARSCEPE-- 353 Query: 347 ITHVLPFEKINEGFD 361 P I E FD Sbjct: 354 -----PERIIPEAFD 363 >5UJU-A nrPDB Length = 576 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 20/73 (27%), Gaps = 4/73 (5%) Query: 220 IIAVDINKDKFAKAKELGATE----CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 +IA D A E+ A I + GGV S + G + Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 276 MMASLLCCHEACG 288 ++ G Sbjct: 523 NQSAAFSDFHGTG 535 >4TXK-A nrPDB Length = 615 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%) Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIA 222 + + C V G G GL A + GA ++ Sbjct: 74 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >2BRY-A nrPDB Length = 497 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%) Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIA 222 + + C V G G GL A + GA ++ Sbjct: 82 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >6GME-A nrPDB Length = 201 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 223 VDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE 268 VD+ ++ A LGAT IN ++++ + E++ F+ + Sbjct: 62 VDVREEGKENAFSLGATLWINSEEFED-LDEIVARYVQPMASFARD 106 >2WWR-A nrPDB Length = 330 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 20/52 (38%), Gaps = 1/52 (1%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 ST + GLG +G + K G R + + +A E A P+ Sbjct: 156 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP-RPEEAAEFQAEFVSTPE 206 >4MOP-A nrPDB Length = 633 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 8/67 (11%) Query: 196 CAVFGLGGVGLSAVMGCK-AAGAA-RIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + G G +G + + GA ++ DI + ++GA N +Y+K I + Sbjct: 49 VVIVGSGPIGCT---YARELVGAGYKVAMFDIGE--IDSGLKIGA-HKKNTVEYQKNIDK 102 Query: 254 VLKEMTD 260 + + Sbjct: 103 FVNVIQG 109 >5NMX-A nrPDB Length = 425 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 10/22 (45%), Positives = 11/22 (50%) Query: 195 TCAVFGLGGVGLSAVMGCKAAG 216 AV G G GL+A K AG Sbjct: 3 RVAVLGAGPSGLTAARYLKQAG 24 >5ZBK-A nrPDB Length = 203 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 21/58 (36%), Gaps = 7/58 (12%) Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCA------VFGLGGVGLS-AVMGCKAAGAARIIAV 223 + CG S G A V G A V+G G VGL V A +I + Sbjct: 8 VFCGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGTVADAALAAGGEVIGI 65 >5UYY-A nrPDB Length = 381 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 50/170 (29%), Gaps = 19/170 (11%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN--PQDYKKPI 251 + G G +G S + K I DI +++ +AKEL ++ D + Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKEL---HVVDEIAVDLQHAC 74 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLT 311 +E +T VIV +++ +N L Sbjct: 75 EE---------AHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALF 125 Query: 312 GRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALI---THVLPFEKINE 358 + + GG V A F I H +P E + E Sbjct: 126 SKEI--SFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHVPNEHVEE 173 >3X43-A nrPDB Length = 332 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 21/60 (35%), Gaps = 2/60 (3%) Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAV--DINKDKFAKAKELGATECINP 244 + PG T G VG++ M A G + + + ++ + G + P Sbjct: 57 KGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFP 116 >3NJ4-A nrPDB Length = 435 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINK-DKFAKAKE 235 G V G G VG + GA R+I +I+ + A E Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAME 258 >1LTH-T nrPDB Length = 319 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 190 VTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAV-DINKDKFAK 232 V P AV G G VG + G AR I + DI K++ Sbjct: 5 VKPTK-LAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >6GBN-A nrPDB Length = 438 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 5/71 (7%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG + + AGA R+I +I+ +A A + + + Sbjct: 218 AGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQA----AMDGYEVKKMADAV 272 Query: 252 QEVLKEMTDGG 262 + +T G Sbjct: 273 KRADIVVTATG 283 >5MH6-A nrPDB Length = 308 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 42/147 (28%), Gaps = 16/147 (10%) Query: 74 VESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTC 133 VE GE PGD V G + + +C++ + + + Sbjct: 32 VEFAGED-EQFGPGDAVA-----SFGHRDAFLDADWVHCIRAGYDEFPVGVYEEAGTYLT 85 Query: 134 RGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 IH T + Y + + + + + Y +A G Sbjct: 86 NSTGIHGTTVGETVAGYMLTFARRL-HAYRDAQHDHAWDLPR-----YEEPFTLA----G 135 Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARI 220 V GLG +G V A G + Sbjct: 136 ERVCVVGLGTLGRGVVDRAAALGMEVV 162 >1WG8-A nrPDB Length = 285 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKEL 236 Y A+++ V PG LGG G + + + R+I +D + + A+AK L Sbjct: 7 VPVLYQEALDLLAVRPGGVYVDATLGGAGHARGILER---GGRVIGLDQDPEAVARAKGL 63 >5FUB-A nrPDB Length = 337 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 16/45 (35%) Query: 199 FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 G G + L + K AG + A + + K+ G + Sbjct: 53 CGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVVT 97 >1HL3-A nrPDB Length = 358 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 13/24 (54%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAG 216 G T + GLG VG + + KA G Sbjct: 171 GETLGIIGLGRVGQAVALRAKAFG 194 >1DOD-A nrPDB Length = 394 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 10/26 (38%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAARII 221 A+ G G GL AG +I Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVI 30 >3DOC-A nrPDB Length = 335 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 41/133 (30%), Gaps = 27/133 (20%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINK-----------------DKFAKAKELG 237 A+ G G +G + + +G I V IN +F K E+ Sbjct: 4 RVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEVEVA 63 Query: 238 ATEC------INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV 291 I + P + KE VD + E G T EA V Sbjct: 64 GDTIDVGYGPIKVHAVRNPAELPWKEEN---VDIALECTGIF-TSRDKAALHLEAGAKRV 119 Query: 292 IVGVPPASQNLSI 304 IV P +L++ Sbjct: 120 IVSAPADGADLTV 132 >2AS0-A nrPDB Length = 396 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 4/47 (8%) Query: 190 VTPGSTCA-VFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 V PG VF G A+ AGA +I +D + AKE Sbjct: 215 VQPGDRVLDVFTY--TGGFAIHAA-IAGADEVIGIDKSPRAIETAKE 258 >5J9G-A nrPDB Length = 338 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 42/129 (32%), Gaps = 24/129 (18%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAA----RIIAVD--INKDKFAKAKELGATE-------- 240 + G G +G A G ++A++ A + +T Sbjct: 4 KIGINGFGRIGRLAFRRIMDLGEKSKDIEVVAINDLTTPALLAHLLKYDSTHGTFDHEVS 63 Query: 241 ------CINPQDYK---KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV 291 ++ + Y+ +P + + + + GVDF E G T A +A V Sbjct: 64 STEDSIVVDGKKYRVYAEPQAQNIPWVKNDGVDFVLECTG-FYTSKAKSQAHLDAGVKRV 122 Query: 292 IVGVPPASQ 300 ++ P + Sbjct: 123 LISAPAGND 131 >4DIM-A nrPDB Length = 403 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 23/72 (31%), Gaps = 6/72 (8%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPI 251 + G G L K G I N K A E+ + NP + Sbjct: 8 KRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNLADEISYMDISNP----DEV 63 Query: 252 QEVLKEMTDGGV 263 ++ +K++ G Sbjct: 64 EQKVKDLNLDGA 75 >2X36-A nrPDB Length = 207 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 15/113 (13%) Query: 149 QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSA 208 Y V + + + + GC T +++A P V + Sbjct: 81 DYLVTSHIHL-HVPEGATPKDGPSAGCTIVTA---LLSLAMGRP-----------VRQNL 125 Query: 209 VMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 M + + +I+ V K+K AK G T + P + KK ++ +T+G Sbjct: 126 AMTGEVSLTGKILPVGGIKEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEG 178 >3OND-A nrPDB Length = 488 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKA 233 G V G G VG K AGA R+I +I+ +A Sbjct: 264 AGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPICALQA 304 >3DC2-A nrPDB Length = 529 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 12/28 (42%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARI 220 G T V GLG +G A GA + Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVV 169 >6HNS-A nrPDB Length = 454 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 12/27 (44%), Gaps = 3/27 (11%) Query: 195 TCAVFGLGGVGLS---AVMGCKAAGAA 218 A+ G G GL+ A A GAA Sbjct: 4 RVAIIGAGPCGLAQLRAFQSAAAKGAA 30 >4LMA-A nrPDB Length = 326 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Query: 181 YGSAVNVAKVTPGSTCAV---FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 SA + P +T V G G+ L+ K + ++ ++ A K G Sbjct: 61 INSAEKAGLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYG 120 Query: 238 ATECINP 244 AT + P Sbjct: 121 ATLELTP 127 >2EFY-A nrPDB Length = 304 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 26/69 (37%), Gaps = 4/69 (5%) Query: 184 AVNVAKVTPGSTCAVF----GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 A + PGS + G G+GL+ + + + +++++ K GA Sbjct: 51 AEERGILRPGSGQVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAE 110 Query: 240 ECINPQDYK 248 + + + Sbjct: 111 LVLTDPERR 119 >4IZO-A nrPDB Length = 419 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 16/36 (44%), Gaps = 1/36 (2%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINK 227 PG+ + G G +G +A G R+ +D + Sbjct: 34 PGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDP 68 >3HDH-A nrPDB Length = 302 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 V G G +G A G ++ VD +D AK+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAKSKK 56 >5M0P-A nrPDB Length = 428 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 16/124 (12%), Positives = 42/124 (33%), Gaps = 15/124 (12%) Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFS--------------FEVIGRLDTMMASLLC 282 GA ++ + + + MT+G +++ E + ++ S++ Sbjct: 88 GAIHTVDGKKHVDRKALFMSLMTEGNLNYVRELTRTLWHANTQRMESMDEVNIYRESIVL 147 Query: 283 CHEACGTSVIVGVPPASQNLSINPMLLLTGR-TWKGAVYGGFKSKEGIPKLVADFMAKKF 341 + V PP M ++ G + G+K+ + + V D++ ++ Sbjct: 148 LTKVGTRWAGVQAPPEDIERIATDMDIMIDSFRALGGAFKGYKASKEARRRVEDWLEEQI 207 Query: 342 SLDA 345 Sbjct: 208 IETR 211 >3HWR-A nrPDB Length = 318 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 30/102 (29%), Gaps = 5/102 (4%) Query: 193 GSTCAVFGLGGVGL-SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G A+ G G VG M +A +I + + G D + + Sbjct: 19 GMKVAIMGAGAVGCYYGGMLARA--GHEVILIA-RPQHVQAIEATGLRLETQSFDEQVKV 75 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 G D + DT A+L A S +V Sbjct: 76 SASSDPSAVQGADLVLFCVKSTDTQSAAL-AMKPALAKSALV 116 >2RIR-A nrPDB Length = 300 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 GS AV GLG G++ A GA + + A+ E+G Sbjct: 157 GSQVAVLGLGRTGMTIARTFAALGA-NVKVGARSSAHLARITEMG 200 >4P4L-A nrPDB Length = 277 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 38/112 (33%), Gaps = 9/112 (8%) Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG-----ATEC--INPQDYKK 249 V G GG +AV+G G I V N DK A+ +LG AT + Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFDSGGLAD 180 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGT--SVIVGVPPAS 299 + ++ + + G L + L ++ T + VG Sbjct: 181 AVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGR 232 >3WGE-A nrPDB Length = 113 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 22/75 (29%), Gaps = 2/75 (2%) Query: 83 TVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGN--PRGTLQDGTRRFTCRGKPIHH 140 V GD I F P CG C+ L + G + C G + Sbjct: 17 HVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 76 Query: 141 FLGTSTFSQYTVVDE 155 + F VD+ Sbjct: 77 YPTLLWFRDGKKVDQ 91 >3PPI-A nrPDB Length = 281 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 27/81 (33%), Gaps = 3/81 (3%) Query: 200 GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG--ATEC-INPQDYKKPIQEVLK 256 G GG+G + V A G +IA + A A ELG A N + + Sbjct: 38 GAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSVLAAIEA 97 Query: 257 EMTDGGVDFSFEVIGRLDTMM 277 G + ++ G Sbjct: 98 ANQLGRLRYAVVAHGGFGVAQ 118 >3JTM-A nrPDB Length = 351 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T G G +G + K G ++ D + KE GA Sbjct: 164 GKTIGTVGAGRIGKLLLQRLKPFG-CNLLYHDRLQMAPELEKETGAKFV 211 >1F14-A nrPDB Length = 310 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 V G G +G A G ++ VD +D AK+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAKSKK 56 >3AOE-E nrPDB Length = 419 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 27/77 (35%), Gaps = 8/77 (10%) Query: 168 EKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDIN- 226 + +G A G+ V GLG VG + + + G R++AV + Sbjct: 194 DDAAGLG-ALLVLEALAKRRGLDLRGARVVVQGLGQVGAAVALHAERLGM-RVVAVATSM 251 Query: 227 -----KDKFAKAKELGA 238 + A+ L A Sbjct: 252 GGMYAPEGLDVAEVLSA 268 >1YPF-A nrPDB Length = 336 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 7/60 (11%) Query: 189 KVTPGSTCAV-----FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE--LGATEC 241 + PG C FG GG L+A+ C A + IIA + AK GAT Sbjct: 177 GIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTNGDVAKSIRFGATMV 236 >6APH-A nrPDB Length = 445 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 16/45 (35%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDK-FAKAKE 235 G V G G VG + AG + + +I+ A E Sbjct: 225 AGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQAAME 268 >1W7I-A nrPDB Length = 795 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 36/111 (32%), Gaps = 1/111 (0%) Query: 73 IVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFT 132 V E + KPGDKV+ L + C +P++ + D T Sbjct: 20 EVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSY 79 Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + H L F ++ + A +P E++ + G Y Sbjct: 80 LHEPAVLHNLKV-RFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129 >3OC4-A nrPDB Length = 452 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAV 209 G+ V + T AV G G +G+ A+ Sbjct: 136 GALAAVPLLENSQTVAVIGAGPIGMEAI 163 >3LLV-A nrPDB Length = 141 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 42/113 (37%), Gaps = 15/113 (13%) Query: 197 AVFG--LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQE 253 V G GVGL V AAG +++AVD +K+K ++ G I +P D + Sbjct: 10 IVIGSEAAGVGL--VRELTAAG-KKVLAVDKSKEKIELLEDEGFDAVIADPTD-----ES 61 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGT---SVIVGVPPASQNLS 303 + + GV + G D +L + V V P + Sbjct: 62 FYRSLDLEGVSAVL-ITGSDDEFNLKILKALRSVSDVYAIVRVSSPKKKEEFE 113 >6ABI-A nrPDB Length = 358 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 16/49 (32%), Gaps = 1/49 (2%) Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFS 266 +II DI K+ GA K + E +T G D Sbjct: 27 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLT-KGYDVV 74 >3OJO-A nrPDB Length = 431 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 3/41 (7%) Query: 193 GSTCAVFGLGGVGL-SAVMGCKAAGAARIIAVDINKDKFAK 232 GS V GLG +GL +++M K ++ VDIN+ K Sbjct: 11 GSKLTVVGLGYIGLPTSIMFAKH--GVDVLGVDINQQTIDK 49 >2E28-A nrPDB Length = 587 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 42/130 (32%), Gaps = 9/130 (6%) Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235 +AV V G + VG + G+ ++ V + D AK + Sbjct: 432 MLDVAVDAAVRSGLVKHGDLVVITAGVPVGET--------GSTNLMKVHVISDLLAKGQG 483 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV-IGRLDTMMASLLCCHEACGTSVIVG 294 +G K +E ++M DGG+ + + + + E G + Sbjct: 484 IGRKSAFGKAVVAKTAEEARQKMVDGGILVTVSTDADMMPAIEKAAAIITEEGGLTSHAA 543 Query: 295 VPPASQNLSI 304 V S + + Sbjct: 544 VVGLSLGIPV 553 >1MV8-A nrPDB Length = 436 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 195 TCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAK 232 ++FGLG VG + GC +A +I VD++ K Sbjct: 2 RISIFGLGYVG-AVCAGCLSARGHEVIGVDVSSTKIDL 38 >1G6Q-1 nrPDB Length = 328 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 19/43 (44%), Gaps = 3/43 (6%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKEL 236 G G G+ ++ K GA +I VD++ AKEL Sbjct: 40 KIVLDVGCGT-GILSMFAAKH-GAKHVIGVDMSSI-IEMAKEL 79 >1FI8-A nrPDB Length = 228 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 31/98 (31%), Gaps = 7/98 (7%) Query: 111 YCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKV 170 +C + + G + + P+ + ++ T+ ++ + K+ + + Sbjct: 45 HCSGSKIQVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 104 Query: 171 CLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSA 208 KV PG C V G G +G Sbjct: 105 VK-------PLNLPRRNVKVKPGDVCYVAGWGKLGPMG 135 >5JFC-L nrPDB Length = 474 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 10/29 (34%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARII 221 G A+ G G GL+ G I Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTI 182 >3H9U-A nrPDB Length = 436 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINK-DKFAKAKE 235 G T V G G VG + GA R++ +++ + A E Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAME 253 >2YU3-A nrPDB Length = 95 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 316 KGAVYGGFKSKEGIPKLVADFMAKKFSLDAL-ITHVLPFEKINEGFDLLHSGKSIRTV 372 G + G ++ + +++ D K + LP +IN+ L S K I+ V Sbjct: 29 AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDVRYKSNLPLTEINKILKNLESKKLIKAV 86 >2DK5-A nrPDB Length = 91 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 316 KGAVYGGFKSKEGIPKLVADFMAKKFSLDAL-ITHVLPFEKINEGFDLLHSGKSIRTV 372 G + G ++ + +++ D K + LP +IN+ L S K I+ V Sbjct: 12 AGKMKGSDNQEKLVYQIIEDAGNKGIWSRDVRYKSNLPLTEINKILKNLESKKLIKAV 69 >3T4P-A nrPDB Length = 334 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 24/67 (35%), Gaps = 3/67 (4%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAV---DINKDKFAKAKELG 237 Y A K+ PG + V G ++ A ++I ++ ++ + G Sbjct: 59 YDKAEKEGKLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFG 118 Query: 238 ATECINP 244 A + P Sbjct: 119 AEVILTP 125 >5XW3-A nrPDB Length = 315 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 27/68 (39%), Gaps = 8/68 (11%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGAARIIAVDINK---DKFAKAKELGA 238 A+ VT G T G G+GL A+ + R+I K +K K LGA Sbjct: 55 ALEKGLVTEGGTIIEPTAGNTGIGL-ALAALQHD--LRVIVCVPEKFSIEKQELMKALGA 111 Query: 239 TECINPQD 246 T P + Sbjct: 112 TVVHTPTE 119 >1OBF-O nrPDB Length = 335 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 19/67 (28%), Gaps = 10/67 (14%) Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGG 322 VD E G T + VI+ P + + G +G Sbjct: 92 VDVVLECTG-FFTTKEKAGAHIKGGAKKVIISAPGGAD---------VDATVVYGVNHGT 141 Query: 323 FKSKEGI 329 KS + + Sbjct: 142 LKSTDTV 148 >1S4D-A nrPDB Length = 280 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 18/44 (40%), Gaps = 4/44 (9%) Query: 195 TCAVFGLGGV--GLSAVMGCKAAGAARIIAVD--INKDKFAKAK 234 + + G G GL + A A +I D +N+D A+ Sbjct: 16 SVWLVGAGPGDPGLLTLHAANALRQADVIVHDALVNEDCLKLAR 59 >1B26-A nrPDB Length = 416 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 24/53 (45%), Gaps = 2/53 (3%) Query: 176 GFSTGYGSAVNVAKVTPGS-TCAVFGLGGVG-LSAVMGCKAAGAARIIAVDIN 226 G G A++V + P T AV G G VG +A++ + G+ + D Sbjct: 192 GVKVCAGLAMDVLGIDPKKATVAVQGFGNVGQFAALLISQELGSKVVAVSDSR 244 >5J46-A nrPDB Length = 189 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 21/47 (44%), Gaps = 9/47 (19%) Query: 199 FGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + G+GL+A R+I +D+++DK INP+ Sbjct: 62 YAAPGIGLAATQVDVH---ERVIVIDVSEDKNEL------RAFINPE 99 >3FEO-A nrPDB Length = 437 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 44 VGICRTDDHVVSGNLVTPLPVIL 66 IC +D H V + P++ Sbjct: 93 CNICGSDIHPVGWCAASGKPLVP 115 >4LMB-A nrPDB Length = 322 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 34/98 (34%), Gaps = 11/98 (11%) Query: 153 VDENAVAKIDAASPLEKV------CLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGL 206 V V K+++ +P V ++ + G V P S G G+ L Sbjct: 35 VKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTILVEPTS-----GNTGIAL 89 Query: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 + V K + ++ ++ A K GA + P Sbjct: 90 AMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTP 127 >3RHA-A nrPDB Length = 482 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 11/23 (47%) Query: 196 CAVFGLGGVGLSAVMGCKAAGAA 218 + G G GL+A K AG + Sbjct: 10 VVIVGAGPSGLTAARELKKAGLS 32 >1ZEJ-A nrPDB Length = 293 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 26/62 (41%), Gaps = 6/62 (9%) Query: 195 TCAVFGLGGVG-LSAVMGC-KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 V G G +G A+ K ++ D+++ A+E E ++ ++ ++ Sbjct: 14 KVFVIGAGLMGRGIAIAIASKH----EVVLQDVSEKALEAAREQIPEELLSKIEFTTTLE 69 Query: 253 EV 254 +V Sbjct: 70 KV 71 >1LSS-A nrPDB Length = 140 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 36/111 (32%), Gaps = 4/111 (3%) Query: 154 DENAVAKIDAA----SPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAV 209 + + ID + E L+ G T + + AV G V L + Sbjct: 28 HDIVLIDIDKDICKKASAEIDALVINGDCTKIKTLEDAGIEDADMYIAVTGKEEVNLMSS 87 Query: 210 MGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 + K+ G + IA + + LG ++P+ E L E Sbjct: 88 LLAKSYGINKTIARISEIEYKDVFERLGVDVVVSPELIAANYIEKLIERPG 138 >1V9C-A nrPDB Length = 218 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 10/104 (9%) Query: 205 GLSAVM-GCKAAGAARIIAVDINKDKFAK----AKELGATECINPQDY----KKPIQEVL 255 GL A+ G + AR+IA +N ++ EL A + + + V Sbjct: 59 GLKAIQAGARILVDARMIACGLNPERLRLFGNEVVELLAHPEVVARAKATGGTRAEAAVA 118 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV-GVPPA 298 G +D + +G T + +L+ +V G+P Sbjct: 119 YAWEKGLLDGAIVGVGNAPTFLLALVEAIRQGARPALVLGMPVG 162 >3EUW-A nrPDB Length = 344 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 28/81 (34%), Gaps = 5/81 (6%) Query: 195 TCAVFGLGGVGLS--AVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY--KKP 250 A+FG G +G A + +IA + A+ GA +P + + Sbjct: 6 RIALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFARDD 65 Query: 251 IQE-VLKEMTDGGVDFSFEVI 270 I V+ T VD + Sbjct: 66 IDGIVIGSPTSTHVDLITRAV 86 >3GRP-A nrPDB Length = 266 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 9/86 (10%) Query: 193 GSTCAVFGL-GGVGLSAVMGCKAAGAARIIAV-DINKDKF-AKAKELGATECINPQDY-- 247 G V G GG+G + A GA I+ + +DK A +LG + + Sbjct: 27 GRKALVTGATGGIGEAIARCFHAQGA--IVGLHGTREDKLKEIAADLGKDVFVFSANLSD 84 Query: 248 KKPIQEV--LKEMTDGGVDFSFEVIG 271 +K I+++ + E G+D G Sbjct: 85 RKSIKQLAEVAEREMEGIDILVNNAG 110 >3GNQ-A nrPDB Length = 344 Score = 28.5 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 11/39 (28%), Gaps = 1/39 (2%) Query: 262 GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300 GVD E G T + VI+ P Sbjct: 100 GVDVVMECTG-FFTSKEKASAHLKGGAKKVIISAPGGKD 137 >3NNK-A nrPDB Length = 411 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 16/46 (34%) Query: 172 LIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA 217 ++ G S A+ V+ + PG V G G + A Sbjct: 67 MLVDGTSRAGIEAILVSAIRPGDKVLVPVFGRFGHLLCEIARRCRA 112 >4RDI-A nrPDB Length = 288 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 18/54 (33%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKF 230 T ++ + V G+GGVG A G I +D++ Sbjct: 34 GGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCV 87 >4F86-A nrPDB Length = 320 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 25/64 (39%), Gaps = 6/64 (9%) Query: 186 NVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFA----KAKELGATEC 241 ++ V PG T G G G + ++ V ++ + +A+ELG + Sbjct: 119 HLGPVGPGDTLVDAGCGRGGSMVM--AHQRFGCKVEGVTLSAAQAEFGNRRARELGIDDH 176 Query: 242 INPQ 245 + + Sbjct: 177 VRSR 180 >4ZV2-A nrPDB Length = 233 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 56/152 (36%), Gaps = 23/152 (15%) Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMM 277 +++ DI+ K A AK+LG P D+ ++ + G +D + + Sbjct: 30 GKLVGFDIDLAK-AIAKKLGVKVEFKPMDFDG----IIPALQSGKIDVVIAGMTITEERK 84 Query: 278 ASLLCCHEA--CGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVAD 335 + G +++V N SI + L G+ V G S++ + K+ D Sbjct: 85 KQVDFSDPYFEAGQAIVV----KKGNDSIKSLEDLKGKKV--GVQLGSTSEQHVKKVAKD 138 Query: 336 FMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 + F+ +E F L SG+ Sbjct: 139 ---AGVKVKK-------FDNFSEAFQELKSGR 160 >6JCV-A nrPDB Length = 333 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 17/45 (37%), Gaps = 1/45 (2%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 G T V G G G + G +I ++ + AK+ G Sbjct: 15 GKTIGVIGYGNQGRVQATIMRENG-LNVIVGNVKDKYYELAKKEG 58 >4X28-D nrPDB Length = 373 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 26/148 (17%), Positives = 45/148 (30%), Gaps = 34/148 (22%) Query: 139 HHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTC-- 196 H + T T +Q + A + + PG Sbjct: 141 HGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAG-------------DPGVAVTA 187 Query: 197 -AVFGLGGVGLSAVMGCKAAGAARIIAVDI----------NKDK-----FAKAKELGATE 240 A GLG VG + G K A R+ D+ ++ + ++ A Sbjct: 188 LATTGLGSVGHLELNGAKVDAARRVGGTDVAVWLGTLSTLSRTAFQLGVLERGLQMTAEY 247 Query: 241 CINPQDYKKPI---QEVLKEMTDGGVDF 265 + + +PI Q V + + DG +D Sbjct: 248 ARTREQFDRPIGSFQAVGQRLADGYIDV 275 >4EJ0-A nrPDB Length = 342 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 3/85 (3%) Query: 195 TCAVFGLGG-VGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 T V G G +G + V G RIIAVD N + K K L E + D + ++ Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVD-NLTRADKFKNLVDCEIDDYLDKTEFVER 72 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMA 278 + G V F DTM Sbjct: 73 FARG-DFGKVRAVFHEGACSDTMET 96 >4GBJ-A nrPDB Length = 297 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 39/125 (31%), Gaps = 14/125 (11%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 A GLG +G AG ++ + K +LGAT N D Sbjct: 6 EKIAFLGLGNLGTPIAEILLEAG-YELVVWNRTASKAEPLTKLGATVVENAIDA------ 58 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGR 313 +T GG+ FS + S+ + V V + S S L Sbjct: 59 ----ITPGGIVFSVLADDAAVEELFSMELVEKLGKDGVHVSMSTISPETS---RQLAQVH 111 Query: 314 TWKGA 318 W GA Sbjct: 112 EWYGA 116 >3LP6-A nrPDB Length = 174 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 12/76 (15%), Positives = 26/76 (34%), Gaps = 5/76 (6%) Query: 149 QYTVVDENAVAKIDAASPLEK-----VCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 + + A + + G G S +++ ++ G A +GG Sbjct: 64 EVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGG 123 Query: 204 VGLSAVMGCKAAGAAR 219 G + ++ + GAA Sbjct: 124 AGNAGLLAVRMLGAAN 139 >1V7L-A nrPDB Length = 163 Score = 28.1 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 17/37 (45%), Gaps = 3/37 (8%) Query: 189 KVTPGSTCA---VFGLGGVGLSAVMGCKAAGAARIIA 222 V PG FG+G SA + KA G A +IA Sbjct: 48 NVRPGDVVVAGKNFGIGSSRESAALALKALGIAGVIA 84 >3T5Y-A nrPDB Length = 357 Score = 28.1 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 10/24 (41%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGG 203 G V A V PG +FG G Sbjct: 304 GLAHLVENALVQPGDRVLLFGGGA 327 >4E4T-A nrPDB Length = 419 Score = 28.1 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 32/106 (30%), Gaps = 11/106 (10%) Query: 192 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGA---TECINPQDYK 248 PG+ + G G +G ++ G R+ +D + A GA D + Sbjct: 34 PGAWLGMVGGGQLGRMFCFAAQSMG-YRVAVLDPDP-----ASPAGAVADRHLRAAYDDE 87 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + E+ V FE + + G V V Sbjct: 88 AALAELAGLCEA--VSTEFENVPAASLDFLARTTFVAPAGRCVAVA 131 >1KON-A nrPDB Length = 249 Score = 28.1 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 9/90 (10%) Query: 201 LGGVGLSAVMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPIQEVLKEM 258 LG G A + K +I+ + + A E GA + + D + +EM Sbjct: 127 LGTDGSVAYLFSK----KGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEM 182 Query: 259 TDGGVDFSFEVIG-RLDTMMASLLCCHEAC 287 G V + E G + D+ S++ +A Sbjct: 183 --GKVRDALEAAGLKADSAEVSMIPSTKAD 210 >6DHM-A nrPDB Length = 582 Score = 27.7 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 19/41 (46%), Gaps = 3/41 (7%) Query: 189 KVTPG---STCAVFGLGGVGLSAVMGCKAAGAARIIAVDIN 226 +TPG T AV G G VGL ++ GA + + + Sbjct: 318 GMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESD 358 >1LU9-A nrPDB Length = 287 Score = 27.7 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 28/165 (16%), Positives = 45/165 (27%), Gaps = 10/165 (6%) Query: 188 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 V + G G VG+ + GA ++ A A + +N Sbjct: 115 GSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNVTAA 174 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM 307 + E G F + + + IV A L I + Sbjct: 175 ETADDASRAEAVKG---AHFVFTAGAIGLELLPQAAWQNESSIEIVADYNAQPPLGIGGI 231 Query: 308 LL------LTGRTWKGAV-YGGFKSKEGIPKLVADFMAKKFSLDA 345 G+ GA+ GG K K + F + + DA Sbjct: 232 DATDKGKEYGGKRAFGALGIGGLKLKLHRACIAKLFESSEGVFDA 276 >3GG9-A nrPDB Length = 352 Score = 27.7 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 23/60 (38%), Gaps = 2/60 (3%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 237 ST + +V G T +FG G +G +A G ++ K +A+ G Sbjct: 145 STTMPPNFGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGM-NVLVWGRENSK-ERARADG 202 >1ZVF-A nrPDB Length = 176 Score = 27.7 bits (60), Expect = 8.4, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 21/60 (35%) Query: 281 LCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKK 340 C H+ T +IVG P + INP + + + PK + + + Sbjct: 28 YCLHKGGFTVMIVGGPNERTDYHINPTPEWFYQKKGSMLLKVVDETDAEPKFIDIIINEG 87 >5YEI-C nrPDB Length = 412 Score = 27.7 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 34/185 (18%), Positives = 54/185 (29%), Gaps = 28/185 (15%) Query: 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G V G GV + + G + V A A L A EC D Sbjct: 122 RADLKAGRVVVVAGFQGVDGNGNITTLGRGGSDTTGV-------ALAAALKADECQIYTD 174 Query: 247 -----------------YKKPIQEVLKEMTDGGVDF----SFEVIGRLDTMMASLLCCHE 285 K E + EM G + E G+ + + L E Sbjct: 175 VDGVYTTDPRVVPQARRLDKITFEEMLEMASLGSKVLQIRAVEFAGKYNVPLRVLHSFQE 234 Query: 286 ACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDA 345 GT + + S I + K + G + K++ A +D Sbjct: 235 GPGTLITIDDEEESMEQPIISGIAFNRDEAKLTIRGVPDTPGVAFKILGPISAANVEVDM 294 Query: 346 LITHV 350 ++ +V Sbjct: 295 IVQNV 299 >2YY8-A nrPDB Length = 201 Score = 27.7 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 34/99 (34%), Gaps = 8/99 (8%) Query: 209 VMGCKAAGAARIIAVDINKDKF-----AKAKELGATECINPQDYKKPIQEVLKEMTDGGV 263 + +A GA II +K K G I ++ + ++V+KE T V Sbjct: 22 ALTARAFGADGIIIASEEDEKVKESVEDVVKRWGGPFFI---EFNRNWRKVMKEFTGVKV 78 Query: 264 DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 302 + + D + + +IVG + + Sbjct: 79 HLTMYGLHVDDVIEELKEKLKKGEDFMIIVGAEKVPREV 117 >4V68-BC nrPDB Length = 191 Score = 27.7 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 31/72 (43%), Gaps = 9/72 (12%) Query: 219 RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMA 278 R++A+ +K +A+E GA +E+++++ DG +DF +G + Sbjct: 50 RVLAIAKG-EKIKEAEEAGADYV--------GGEEIIQKILDGWMDFVMGAVGSKLGRIL 100 Query: 279 SLLCCHEACGTS 290 + GT Sbjct: 101 GPRGLNPKAGTV 112 >4D3F-A nrPDB Length = 310 Score = 27.7 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 26/74 (35%), Gaps = 1/74 (1%) Query: 194 STCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + V GLG +G + G + + + K + GA + + Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYS-VTVWNRTSSKADQLVAKGAIRVSTVNEALAANEL 80 Query: 254 VLKEMTDGGVDFSF 267 V+ +TD V +S Sbjct: 81 VILSLTDYNVMYSI 94 >3BA1-A nrPDB Length = 333 Score = 27.4 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 7/23 (30%), Positives = 11/23 (47%) Query: 193 GSTCAVFGLGGVGLSAVMGCKAA 215 G + GLG +GL+ +A Sbjct: 164 GKRVGIIGLGRIGLAVAERAEAF 186 >2AG5-A nrPDB Length = 246 Score = 27.4 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 3/62 (4%) Query: 211 GCKAAGAARIIAVDINKDKF-AKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV 269 A A++IA DIN+ K K G + KK I + E+ +D F V Sbjct: 24 LAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVER--LDVLFNV 81 Query: 270 IG 271 G Sbjct: 82 AG 83 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.132 0.357 Lambda K H 0.267 0.0404 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,330,667 Number of Sequences: 36641 Number of extensions: 610558 Number of successful extensions: 3454 Number of sequences better than 10.0: 353 Number of HSP's better than 10.0 without gapping: 277 Number of HSP's successfully gapped in prelim test: 191 Number of HSP's that attempted gapping in prelim test: 2529 Number of HSP's gapped (non-prelim): 551 length of query: 375 length of database: 10,336,785 effective HSP length: 99 effective length of query: 276 effective length of database: 6,709,326 effective search space: 1851773976 effective search space used: 1851773976 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)