BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O95861 (308 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2WEF-A nrPDB 624 e-179 1JP4-A nrPDB 582 e-167 4QXD-A nrPDB 94 5e-20 1INP-A nrPDB 75 4e-14 2CZH-A nrPDB 54 1e-07 6IB8-A nrPDB 54 1e-07 5J16-A nrPDB 49 3e-06 2BJI-A nrPDB 48 4e-06 4O7I-A nrPDB 48 5e-06 1IMD-A nrPDB 47 8e-06 5ZHH-A nrPDB 47 1e-05 3LV0-A nrPDB 43 2e-04 5DJK-A nrPDB 43 2e-04 5YHT-A nrPDB 43 2e-04 2PCR-A nrPDB 42 3e-04 2P3V-A nrPDB 42 5e-04 4AS5-A nrPDB 41 7e-04 5EQA-A nrPDB 40 0.001 4N81-A nrPDB 37 0.008 3B8B-A nrPDB 35 0.060 5ESY-A nrPDB 34 0.073 1LBZ-A nrPDB 29 2.1 5KZQ-A nrPDB 29 3.3 6QX9-62 nrPDB 28 4.3 1VDW-A nrPDB 28 4.3 5CNI-A nrPDB 28 4.8 5LV0-A nrPDB 28 5.8 1T3I-A nrPDB 28 6.2 5A7Z-A nrPDB 27 9.5 5A7Y-A nrPDB 27 9.9 >2WEF-A nrPDB Length = 311 Score = 624 bits (1609), Expect = e-179, Method: Compositional matrix adjust. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 6 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARK 65 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARK Sbjct: 2 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARK 61 Query: 66 FPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEY 125 FPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEY Sbjct: 62 FPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEY 121 Query: 126 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV 185 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV Sbjct: 122 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV 181 Query: 186 PAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKK 245 PAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKK Sbjct: 182 PAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKK 241 Query: 246 WDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNA 305 WDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNA Sbjct: 242 WDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNA 301 Query: 306 LVP 308 LVP Sbjct: 302 LVP 304 >1JP4-A nrPDB Length = 308 Score = 582 bits (1499), Expect = e-167, Method: Compositional matrix adjust. Identities = 281/308 (91%), Positives = 294/308 (95%) Query: 1 MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICS 60 MASS+ VLMRLVASAYSIAQKAG IVR VIAEGDLGIV+KT ATDLQTKADR+ QMSICS Sbjct: 1 MASSHNVLMRLVASAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICS 60 Query: 61 SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLD 120 SL+RKFPKLTIIGEEDLP EVDQELIED Q EEILKQPCPSQYSAIKEEDLVVWVDP+D Sbjct: 61 SLSRKFPKLTIIGEEDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWVDPVD 120 Query: 121 GTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGF 180 GTKEYTEGLLDNVTVLIGIAYEGKAIAG+INQPYYNY+AGPDAVLGRTIWGVLGLGAFGF Sbjct: 121 GTKEYTEGLLDNVTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGF 180 Query: 181 QLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFAS 240 QLKE PAGKHIITTTRSHSNKLVTDC+AAMNPD VLRVGGAGNKIIQLIEGKASAYVFAS Sbjct: 181 QLKEAPAGKHIITTTRSHSNKLVTDCIAAMNPDNVLRVGGAGNKIIQLIEGKASAYVFAS 240 Query: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPE 300 PGCKKWDTCAPEVILHAVGGKLTDIHGN LQY K+VKHMNSAGVLA LRNY+YYASRVPE Sbjct: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNPLQYDKEVKHMNSAGVLAALRNYEYYASRVPE 300 Query: 301 SIKNALVP 308 S+K+AL+P Sbjct: 301 SVKSALIP 308 >4QXD-A nrPDB Length = 293 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 72/226 (31%), Positives = 110/226 (48%), Gaps = 20/226 (8%) Query: 48 TKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPS-QYSA 106 T+ D +Q I S + K+P + IIGEED+ + I D+Q I + S + Sbjct: 42 TQVDTQSQQIIFSIIKNKYPTINIIGEEDV------ENGIPDNQLPTITQLSFGSLENKI 95 Query: 107 IKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLG 166 I D++++VDPLDGT YT D+V VL+G+ Y+GK + G++++P+YN E Sbjct: 96 ININDIIIYVDPLDGTDCYTHKQYDSVCVLVGVTYKGKPMIGIVSKPFYNNEI------- 148 Query: 167 RTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKII 226 + + + P II S N + + +P V GG+G K++ Sbjct: 149 -----TFAIENYISSISLQPLNDKIIFVC-SKKNDIQHLIKSFPDPYEVKYKGGSGAKMM 202 Query: 227 QLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQY 272 +I +A Y WDT A +VIL A GG + DI+GN L Y Sbjct: 203 AIIHQEADIYYHPLIQSCTWDTLAAQVILEAQGGIVCDIYGNPLCY 248 >1INP-A nrPDB Length = 400 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 76/290 (26%), Positives = 113/290 (38%), Gaps = 67/290 (23%) Query: 43 ATDLQTKADRLAQMSICSSLARKFPKL--TIIGEE------DL---------PSEE---- 81 A D +T AD L Q I ++ KFP L I GEE DL P+EE Sbjct: 46 AVDFKTLADVLVQEVIKENMENKFPGLGKKIFGEESNELTNDLGEKIIMRLGPTEEETVA 105 Query: 82 -----------VDQELIEDSQWEEILKQPC-PSQYSAIKEEDLVVWVDPLDGTKEYTEGL 129 + L + + P S I ++ L +WVDP+D T +Y +G Sbjct: 106 LLSKVLNGNKLASEALAKVVHQDVFFSDPALDSVEINIPQDILGIWVDPIDSTYQYIKGS 165 Query: 130 LD-------------NVTVLIGI--AYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLG 174 D VTVLIG+ G + GVINQP+ + + G+ WG+ Sbjct: 166 ADITPNQGIFPSGLQCVTVLIGVYDIQTGVPLMGVINQPFVSQDLHTRRWKGQCYWGLSY 225 Query: 175 LG-------------------AFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAV 215 LG + G Q + + + ++ + + + Sbjct: 226 LGTNIHSLLPPVSTRSNSEAQSQGTQNPSSEGSCRFSVVISTSEKETIKGALSHVCGERI 285 Query: 216 LRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDI 265 R GAG K + +I G A Y+F+ KWD+CA IL A+GG + D+ Sbjct: 286 FRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMGGGMVDL 335 >2CZH-A nrPDB Length = 299 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 102/271 (37%), Gaps = 52/271 (19%) Query: 14 SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 73 +A +A +AG I+R+ + E + + KT A DL T+ D L + I S L +FP I Sbjct: 33 AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 91 Query: 74 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTEGLLDN 132 EE S C +S W+ DP+DGT + Sbjct: 92 EEAAAS-----------------GAKCVLTHSP-------TWIIDPIDGTCNFVH-RFPT 126 Query: 133 VTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLK---EVPA 187 V V IG A + GVI Y+ E R G G GAF G +L+ E Sbjct: 127 VAVSIGFAVRQELEFGVI---YHCTEE-------RLYTGRRGRGAFCNGQRLRVSGETDL 176 Query: 188 GKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKII--------QLIEGKASAYVFA 239 K ++ T T + N + +L G ++I L G A AY Sbjct: 177 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 236 Query: 240 SPGCKKWDTCAPEVILHAVGGKLTDIHGNVL 270 C WD A VI+ GG + D G L Sbjct: 237 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 265 >6IB8-A nrPDB Length = 271 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 67/264 (25%), Positives = 102/264 (38%), Gaps = 50/264 (18%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A A+KAG ++ + D + + D T D+ A+ I ++ + +P+ TII E Sbjct: 12 AVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITE 71 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E E DQ D QW +DPLDGT + + L + Sbjct: 72 ESGELEGTDQ----DVQW----------------------VIDPLDGTTNFIK-RLPHFA 104 Query: 135 VLIGIAYEGKAIAGVINQPYYN--YEA--GPDAVL------GRTIWGVLG-LGAFGFQLK 183 V I + +G+ V+ P N + A G A L G T + G + A GF K Sbjct: 105 VSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK 164 Query: 184 EVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGC 243 K TT + KL +C R G A + + G+ F G Sbjct: 165 ----AKQYATTYINIVGKLFNECA------DFRRTGSAALDLAYVAAGRVDG--FFEIGL 212 Query: 244 KKWDTCAPEVILHAVGGKLTDIHG 267 + WD A E+++ GG ++D G Sbjct: 213 RPWDFAAGELLVREAGGIVSDFTG 236 >5J16-A nrPDB Length = 283 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 62/267 (23%), Positives = 107/267 (40%), Gaps = 41/267 (15%) Query: 9 MRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPK 68 M L A + Q+AG+ +++++ E +L I K+ DL T D+ + I ++ +P Sbjct: 9 MALYGFAQGLIQEAGIRIKQLM-EQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPN 67 Query: 69 LTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTE 127 ++GEE I VWV DP+DGT + Sbjct: 68 HQVLGEE--------------------------GHGHDIDTSKGTVWVVDPIDGTLNFVH 101 Query: 128 GLLDNVTVLIGIAYEGKAIAG----VINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLK 183 +N + IGI +GK AG V+ Y+ + G A G L L+ Sbjct: 102 -QQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLN----DSNLR 156 Query: 184 EVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGC 243 + G + T+ ++ + V + + G A +I+ + G AY+ +P Sbjct: 157 QSIIGINPNWLTKPILGEIFKEIVN--DSRSARAYGSAALEIVSVATGNLEAYM--TPRL 212 Query: 244 KKWDTCAPEVILHAVGGKLTDIHGNVL 270 + WD VIL+ V G+ +++ G L Sbjct: 213 QPWDFAGGLVILYEVNGQASNLLGEPL 239 >2BJI-A nrPDB Length = 277 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 66/271 (24%), Positives = 106/271 (39%), Gaps = 60/271 (22%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A ++A +AG +VR + + ++ I+ K+ DL T D+ + + +S+ K+P + IGE Sbjct: 12 AVTLAGQAGEVVREAL-KNEMNIMVKSSPADLVTATDQKVEKMLITSIKEKYPSHSFIGE 70 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E + + E L ++ W +DP+DGT + G V Sbjct: 71 ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVHG-FPFVA 106 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 194 V IG K G++ Y D + G G GAF K + + IT Sbjct: 107 VSIGFVVNKKMEFGIV------YSCLED----KMYTGRKGKGAFCNGQKLQVSHQEDITK 156 Query: 195 TRSHSNKLVTDCVAAMNPDAV-----------------LR-VGGAGNKIIQLIEGKASAY 236 + LVT+ ++ P+ V +R VG A + + G A AY Sbjct: 157 SL-----LVTELGSSRTPETVRIILSNIERLLCLPIHGIRGVGTAALNMCLVAAGAADAY 211 Query: 237 VFASPGCKKWDTCAPEVILHAVGGKLTDIHG 267 C WD +I+ GG L D+ G Sbjct: 212 YEMGIHC--WDVAGAGIIVTEAGGVLLDVTG 240 >4O7I-A nrPDB Length = 325 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 65/279 (23%), Positives = 110/279 (39%), Gaps = 63/279 (22%) Query: 48 TKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQ--YS 105 T D Q + + FP+ I+ EED + E+I + C YS Sbjct: 43 TVGDYSVQAYVNKKIHETFPEDQIVAEEDTKTIP-----------EDIFAKVCKHVQIYS 91 Query: 106 AIKEEDLVV--------------WV-DPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVI 150 +K++++ WV DP+DGT + + V + +G GV+ Sbjct: 92 DMKDDEIRKSIDLGNSTGGKGRHWVLDPIDGTLGFLR--REQYAVCLAFMIDGDIKVGVL 149 Query: 151 NQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGK--HIITTTR------------ 196 P N+E G + G GA F + ++ GK H+ TT + Sbjct: 150 GCP--NFEGG------LIVAAQKGCGAKMFSVNDIKNGKDIHVSTTPKTSDMCFCESVEV 201 Query: 197 SHSN----KLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGC----KKWDT 248 SH++ K +T+ + P + + K + + G+A Y+ K WD Sbjct: 202 SHTDQSRSKTITERLQVTKPPVRM---DSQCKYMAIASGRADVYLRLPRNLSYQEKIWDH 258 Query: 249 CAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLAT 287 A +I+ GGK+TDI+GN L + N+ G++A+ Sbjct: 259 AAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHGIVAS 297 >1IMD-A nrPDB Length = 277 Score = 47.4 bits (111), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 65/271 (23%), Positives = 103/271 (38%), Gaps = 60/271 (22%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A ++A++AG +V I + ++ ++ K+ DL T D+ + + SS+ K+P + IGE Sbjct: 12 AVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E + + E L ++ W +DP+DGT + V Sbjct: 71 ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVH-RFPFVA 106 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 194 V IG A K GV+ V G+ G GAF K + + IT Sbjct: 107 VSIGFAVNKKIEFGVVYS----------CVEGKMYTARKGKGAFCNGQKLQVSQQEDITK 156 Query: 195 TRSHSNKLVTDCVAAMNPDAV------------------LRVGGAGNKIIQLIEGKASAY 236 + LVT+ ++ P+ V VG A + + G A AY Sbjct: 157 SL-----LVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAY 211 Query: 237 VFASPGCKKWDTCAPEVILHAVGGKLTDIHG 267 C WD +I+ GG L D+ G Sbjct: 212 YEMGIHC--WDVAGAGIIVTEAGGVLMDVTG 240 >5ZHH-A nrPDB Length = 270 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 57/240 (23%), Positives = 81/240 (33%), Gaps = 54/240 (22%) Query: 37 IVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEIL 96 I EK DL T AD+ ++ + + R FP+ +I+ EE D E + W Sbjct: 33 ITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGNQDNEYL----WA--- 85 Query: 97 KQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYN 156 +DPLDGT Y V IG+ G GVI P+++ Sbjct: 86 -------------------IDPLDGTTNYAH-QYPAFCVSIGLLINGVPQVGVIYDPFHD 125 Query: 157 YEAGPDAVLGRT-------------IWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLV 203 A LG T + L + F + +E P N Sbjct: 126 ELFRGAAGLGATRNRRPIKVSDTSELSKSLLVTGFAYDRRETP------------DNNYA 173 Query: 204 TDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLT 263 C V R G A + + G+ Y G WD A ++L GGK+T Sbjct: 174 EFCHLTHLTQGVRRSGSAALDLAHVACGRVDGY--WERGISPWDVVAGVILLEEAGGKVT 231 >3LV0-A nrPDB Length = 267 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/135 (31%), Positives = 58/135 (42%), Gaps = 27/135 (20%) Query: 19 AQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLP 78 A KAG + R E V D ++ADR A+ I + L++ PK + EE Sbjct: 18 AMKAGRSLVRDYGEVQNLQVSLKGPADYVSQADRKAEKIIFNELSKARPKFGFLMEE--- 74 Query: 79 SEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIG 138 SEE+ + EDSQ I VDPLDGT + G + V I Sbjct: 75 SEEI---IGEDSQHRFI--------------------VDPLDGTTNFLHG-IPFFAVSIA 110 Query: 139 IAYEGKAIAGVINQP 153 + +GK +AGVI P Sbjct: 111 LESQGKIVAGVIYNP 125 >5DJK-A nrPDB Length = 288 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 45/169 (26%), Positives = 69/169 (40%), Gaps = 24/169 (14%) Query: 114 VWV-DPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVL------- 165 VW+ DPLDGT+E++ D+ V I + I A + V Sbjct: 108 VWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTDTVTS 167 Query: 166 GRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKI 225 G GV G PA H I T A+ P + +G AG K Sbjct: 168 GAAPAGVPGTLRIAVSATRPPAVLHRIRQT------------LAIQP---VSIGSAGAKA 212 Query: 226 IQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHK 274 + +I+G AY+ A G +WD+ AP ++ A G + + G+ L+Y++ Sbjct: 213 MAVIDGYVDAYLHAG-GQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQ 260 >5YHT-A nrPDB Length = 267 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 96/264 (36%), Gaps = 50/264 (18%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A ++A +A + R DL I K T + T ADR + + +L R P ++GE Sbjct: 16 ALALADRADELTRVRFGALDLRIDTKPDLTPV-TDADRAVESDVRQTLGRDRPGDGVLGE 74 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E S QW VDP+DGTK + G+ + Sbjct: 75 EFGGSTT-----FTGRQWI----------------------VDPIDGTKNFVRGVPVWAS 107 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 194 LI + +G GV++ P L R W G GAF P + + Sbjct: 108 -LIALLEDGVPSVGVVSAP----------ALQRRWWAARGRGAFASVDGARPHRLSVSSV 156 Query: 195 TRSHSNKLVTDCVAAMN-----------PDAVLRVGGAGNKIIQLIEGKASAYVFASPGC 243 HS L ++ D V RV G+ + + + + + A P Sbjct: 157 AELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQV 216 Query: 244 KKWDTCAPEVILHAVGGKLTDIHG 267 WD A ++++ GG+LT + G Sbjct: 217 SVWDLAALDIVVREAGGRLTSLDG 240 >2PCR-A nrPDB Length = 264 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 53/237 (22%), Positives = 91/237 (38%), Gaps = 51/237 (21%) Query: 38 VEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILK 97 +E+ D + D+ ++ I + + FP ++GEE + +E E +W Sbjct: 34 IEEKGEKDFVSYVDKTSEERIKEVILKFFPDHEVVGEE-MGAEGSGSEY----RW----- 83 Query: 98 QPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNY 157 ++DPLDGTK Y G V +G+ + I G + PY++ Sbjct: 84 -----------------FIDPLDGTKNYING-FPIFAVSVGLVKGEEPIVGAVYLPYFD- 124 Query: 158 EAGPDAVLGRTIWGVLGLGAF----GFQLKEVPAGKH--IITTTRSHSNKLVTDCVAAMN 211 + WG GLGA+ ++K+ + KH ++ S S + ++ + Sbjct: 125 ---------KLYWGAKGLGAYVNGKRIKVKDNESLKHAGVVYGFPSRSRRDISIYLNIFK 175 Query: 212 P-----DAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLT 263 ++ R G A + + EG + K WD A VIL GG T Sbjct: 176 DVFYEVGSMRRPGAAAVDLCMVAEGIFDGMM--EFEMKPWDITAGLVILKEAGGVYT 230 >2P3V-A nrPDB Length = 256 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 57/249 (22%), Positives = 88/249 (35%), Gaps = 77/249 (30%) Query: 39 EKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQ 98 +KT D+ T+ DR AQ I + + FP I+ EE Sbjct: 30 KKTGFKDIVTEIDREAQRMIVDEIRKFFPDENIMAEE----------------------- 66 Query: 99 PCPSQYSAIKEEDLVVWV-DPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNY 157 I E+ +W+ DP+DGT + G L N ++ + G+ GV++ P Sbjct: 67 -------GIFEKGDRLWIIDPIDGTINFVHG-LPNFSISLAYVENGEVKLGVVHAP---- 114 Query: 158 EAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLR 217 L T++ G GAF G+ I R N + +CV + Sbjct: 115 ------ALNETLYAEEGSGAF-------FNGERI----RVSENASLEECVGSTGSYVDFT 157 Query: 218 VGGAGNKIIQLIEGKA------------SAYV-------FASPGCKKWDTCAPEVILHAV 258 K I+ +E + +AYV F + WD A +I+ Sbjct: 158 -----GKFIERMEKRTRRIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEA 212 Query: 259 GGKLTDIHG 267 GG +TD G Sbjct: 213 GGMVTDFSG 221 >4AS5-A nrPDB Length = 277 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 62/266 (23%), Positives = 102/266 (38%), Gaps = 50/266 (18%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A +A++AG ++R + + ++ ++ K+ DL T D+ + + SS+ K+P + IGE Sbjct: 12 AVILARQAGEMIREAL-KNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGE 70 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E + + E E W +DP+DGT + V Sbjct: 71 ESVAAGE-KTVFTEQPTW----------------------VIDPIDGTTNFVH-RFPFVA 106 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQL---KEVPAGK 189 V IG + G++ Y D + G G GAF G +L ++ K Sbjct: 107 VSIGFLVNKEMEFGIV------YSCVED----KMYTGRKGKGAFCNGQKLQVSQQEDITK 156 Query: 190 HIITTTRSHSNKLVTDCVAAMNPD--------AVLRVGGAGNKIIQLIEGKASAYVFASP 241 ++ T S K T + N + + VG A + + G A AY Sbjct: 157 SLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGI 216 Query: 242 GCKKWDTCAPEVILHAVGGKLTDIHG 267 C WD +I+ GG L D+ G Sbjct: 217 HC--WDMAGAGIIVTEAGGVLMDVTG 240 >5EQA-A nrPDB Length = 277 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 27/135 (20%) Query: 19 AQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLP 78 A AG ++R+ + + I+ K + + T AD+ A+ ++ S + FP + GEE Sbjct: 25 ANAAGDVIRKYFRKNNFDIIHKNDLSPV-TIADQSAEEAMVSVILDNFPSHAVYGEE--- 80 Query: 79 SEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIG 138 W C Q SA D V +DP+DGTK + G LI Sbjct: 81 -----------KGWR------C-KQDSA----DYVWVLDPIDGTKSFITG-KPLFGTLIA 117 Query: 139 IAYEGKAIAGVINQP 153 + G I G+I+QP Sbjct: 118 LLQNGTPILGIIDQP 132 >4N81-A nrPDB Length = 259 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 30/110 (27%) Query: 48 TKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAI 107 TKADR A+ ++ + L ++ P+ I GEE Sbjct: 44 TKADRGAEQAMRAILEQERPEDGIFGEE----------------------------MGVS 75 Query: 108 KEEDLVVWV-DPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYN 156 + + +WV DP+DGT+ + G + LI + +G+ + G+INQP + Sbjct: 76 RPDARRLWVLDPIDGTRAFIGGRA-SFGTLIALVEDGRPVLGIINQPIHQ 124 >3B8B-A nrPDB Length = 292 Score = 34.7 bits (78), Expect = 0.060, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 69/167 (41%), Gaps = 31/167 (18%) Query: 104 YSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQP-----YYNYE 158 Y+ + D + VDPLDGTKE+ + TV I + + GVI P Y+ Sbjct: 92 YAVRRGWDTLWIVDPLDGTKEFIK-RNGEFTVNIALVQNAVPVMGVIYVPVKKELYF--- 147 Query: 159 AGPDAVLGRTIW---GVLGLGAFGFQLKEV----------PAGKHII-TTTRSHSNKLVT 204 AV G + G++GL G L+++ A H I +RSH Sbjct: 148 ----AVEGTGAYKCSGIVGLEDEGVTLQQMIEKSERMPLADARDHFIAVASRSHLTPETE 203 Query: 205 DCVAAMNP---DAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDT 248 +A + + L G+ KI + EGKA Y +P +WDT Sbjct: 204 TYIADLKKKHGNVELISSGSSIKICLVAEGKADVYPRFAP-TMEWDT 249 >5ESY-A nrPDB Length = 346 Score = 34.3 bits (77), Expect = 0.073, Method: Compositional matrix adjust. Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 3/40 (7%) Query: 115 WV-DPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQP 153 WV DP+DGTK + G D V +G+ EGK + GV+ P Sbjct: 131 WVLDPIDGTKGFLRG--DQYAVALGLLEEGKVVLGVLACP 168 >1LBZ-A nrPDB Length = 252 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Query: 55 QMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCP---SQYSAIKEED 111 + +I S R+ K +G++ P++ D+ + ED+ E + K+ + + E D Sbjct: 18 RKAIASMPLRERVKDVGMGKDGTPTKAADR-VAEDAALEILRKERVTVVTEESGVLGEGD 76 Query: 112 LVVWVDPLDGTKEYTEGL 129 + V +DPLDGT T G+ Sbjct: 77 VFVALDPLDGTFNATRGI 94 >5KZQ-A nrPDB Length = 570 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Query: 250 APEVILHAVGGKLTDIH---GNVLQYHK--DVKHMNSAGVLATLRNYDYYASRVPESIKN 304 AP I +GG +D+ N+L+ + + + +++ L+ YDY+A VP Sbjct: 132 APTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQ 191 Query: 305 A 305 A Sbjct: 192 A 192 >6QX9-62 nrPDB Length = 95 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 25/38 (65%) Query: 61 SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQ 98 S+ F + +++ LP++EVD +L++D+ +E L+Q Sbjct: 56 SVKNCFIRGSVVRYVQLPADEVDTQLLQDAARKEALQQ 93 >1VDW-A nrPDB Length = 254 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 43/179 (24%), Positives = 68/179 (37%), Gaps = 33/179 (18%) Query: 111 DLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIW 170 D V VDPLDG+ + G + V + I +E I I +P ++ R Sbjct: 78 DYTVVVDPLDGSYNFING-IPFFAVSVAIFHEKDPIYAFIYEP----------IVERLYE 126 Query: 171 GVLGLGAF----GFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLR---VGGAGN 223 G+ G G++ +++E+ I T+ K++ D V R +G Sbjct: 127 GIPGKGSYLNGEKIKVRELAEKPSISFYTKGKGTKII---------DKVKRTRTLGAIAL 177 Query: 224 KIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSA 282 ++ L G A V + D A VI G + D+ G KDV+ SA Sbjct: 178 ELAYLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDG------KDVEITFSA 230 >5CNI-A nrPDB Length = 503 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Query: 250 APEVILHAVGGKLTDIH---GNVLQYHK--DVKHMNSAGVLATLRNYDYYASRVPESIKN 304 AP I +GG +D+ N+L+ + + + +++ L+ YDY+A VP Sbjct: 134 APTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQ 193 Query: 305 A 305 A Sbjct: 194 A 194 >5LV0-A nrPDB Length = 686 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 26/125 (20%) Query: 48 TKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQ---- 103 T AD + +M+ S +R L + ++ P E ++E I + + K+ C + Sbjct: 280 THADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILN-----LKKKECKDRGFEY 334 Query: 104 ----------YSAIKEEDLVVWVDPLDGTKEY------TEGLLDNVTVLIGIAYEGKAIA 147 Y + E+L +D + KEY TEGLL+ L+G+++E A Sbjct: 335 DGKINAWDLYYYMTQTEELKYSIDQ-EFLKEYFPIEVVTEGLLNTYQELLGLSFEQMTDA 393 Query: 148 GVINQ 152 V N+ Sbjct: 394 HVWNK 398 >1T3I-A nrPDB Length = 420 Score = 27.7 bits (60), Expect = 6.2, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 29/65 (44%) Query: 154 YYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPD 213 + N + + V R + L A+ + + + AG IITT H + LV + A Sbjct: 84 FINARSPREIVYTRNATEAINLVAYSWGMNNLKAGDEIITTVMEHHSNLVPWQMVAAKTG 143 Query: 214 AVLRV 218 AVL+ Sbjct: 144 AVLKF 148 >5A7Z-A nrPDB Length = 269 Score = 27.3 bits (59), Expect = 9.5, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 24/117 (20%) Query: 34 DLGIVEKTCATDLQTKADRLAQMSICSSLARKF---PKLTIIGEEDLPSEEVDQELIEDS 90 DLG+ E + + K L Q+ +C S+ RKF LT++G+ D Sbjct: 113 DLGLFE---FLNEEEKEKTLLQVDLCLSVIRKFLWDGNLTVVGKADY------------- 156 Query: 91 QWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLD-NVTVLIGIAYEGKAI 146 +L + Q ++ +ED V +DP + L D NV V+ GI +G+ + Sbjct: 157 ----VLGRANIVQSLSLSDEDNPVILDPYGDVVATDQILRDHNVFVIGGIVDKGRRL 209 >5A7Y-A nrPDB Length = 312 Score = 26.9 bits (58), Expect = 9.9, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 24/117 (20%) Query: 34 DLGIVEKTCATDLQTKADRLAQMSICSSLARKF---PKLTIIGEEDLPSEEVDQELIEDS 90 DLG+ E + + K L Q+ +C S+ RKF LT++G+ D Sbjct: 113 DLGLFE---FLNEEEKEKTLLQVDLCLSVIRKFLWDGNLTVVGKADY------------- 156 Query: 91 QWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLD-NVTVLIGIAYEGKAI 146 +L + Q ++ +ED V +DP + L D NV V+ GI +G+ + Sbjct: 157 ----VLGRANIVQSLSLSDEDNPVILDPYGDVVATDQILRDHNVFVIGGIVDKGRRL 209 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1JP4-A nrPDB 412 e-116 2WEF-A nrPDB 410 e-115 4AS5-A nrPDB 218 3e-57 1IMD-A nrPDB 217 4e-57 2BJI-A nrPDB 211 3e-55 5J16-A nrPDB 202 2e-52 4QXD-A nrPDB 201 3e-52 2CZH-A nrPDB 200 4e-52 6IB8-A nrPDB 190 8e-49 5ZHH-A nrPDB 189 1e-48 4O7I-A nrPDB 182 1e-46 1INP-A nrPDB 177 7e-45 2PCR-A nrPDB 173 9e-44 5YHT-A nrPDB 164 5e-41 2P3V-A nrPDB 159 1e-39 3LV0-A nrPDB 157 9e-39 5DJK-A nrPDB 134 4e-32 5EQA-A nrPDB 131 4e-31 Sequences not found previously or not previously below threshold: 1KA0-A nrPDB 129 2e-30 5ESY-A nrPDB 103 1e-22 4N81-A nrPDB 99 2e-21 2Q74-A nrPDB 97 1e-20 3B8B-A nrPDB 91 5e-19 3QMF-A nrPDB 90 1e-18 1VDW-A nrPDB 90 2e-18 1XI6-A nrPDB 87 1e-17 1G0H-A nrPDB 85 5e-17 1LBZ-A nrPDB 68 4e-12 3OBY-A nrPDB 30 1.6 3C94-A nrPDB 29 2.1 3ZIF-A nrPDB 29 2.3 5EUA-A nrPDB 29 3.2 5HJK-A nrPDB 29 3.4 3GOC-A nrPDB 28 4.4 1IYW-A nrPDB 28 4.4 >1JP4-A nrPDB Length = 308 Score = 412 bits (1059), Expect = e-116, Method: Composition-based stats. Identities = 281/308 (91%), Positives = 294/308 (95%) Query: 1 MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICS 60 MASS+ VLMRLVASAYSIAQKAG IVR VIAEGDLGIV+KT ATDLQTKADR+ QMSICS Sbjct: 1 MASSHNVLMRLVASAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICS 60 Query: 61 SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLD 120 SL+RKFPKLTIIGEEDLP EVDQELIED Q EEILKQPCPSQYSAIKEEDLVVWVDP+D Sbjct: 61 SLSRKFPKLTIIGEEDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWVDPVD 120 Query: 121 GTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGF 180 GTKEYTEGLLDNVTVLIGIAYEGKAIAG+INQPYYNY+AGPDAVLGRTIWGVLGLGAFGF Sbjct: 121 GTKEYTEGLLDNVTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGF 180 Query: 181 QLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFAS 240 QLKE PAGKHIITTTRSHSNKLVTDC+AAMNPD VLRVGGAGNKIIQLIEGKASAYVFAS Sbjct: 181 QLKEAPAGKHIITTTRSHSNKLVTDCIAAMNPDNVLRVGGAGNKIIQLIEGKASAYVFAS 240 Query: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPE 300 PGCKKWDTCAPEVILHAVGGKLTDIHGN LQY K+VKHMNSAGVLA LRNY+YYASRVPE Sbjct: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNPLQYDKEVKHMNSAGVLAALRNYEYYASRVPE 300 Query: 301 SIKNALVP 308 S+K+AL+P Sbjct: 301 SVKSALIP 308 >2WEF-A nrPDB Length = 311 Score = 410 bits (1052), Expect = e-115, Method: Composition-based stats. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 6 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARK 65 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARK Sbjct: 2 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARK 61 Query: 66 FPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEY 125 FPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEY Sbjct: 62 FPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEY 121 Query: 126 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV 185 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV Sbjct: 122 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV 181 Query: 186 PAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKK 245 PAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKK Sbjct: 182 PAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKK 241 Query: 246 WDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNA 305 WDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNA Sbjct: 242 WDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNA 301 Query: 306 LVP 308 LVP Sbjct: 302 LVP 304 >4AS5-A nrPDB Length = 277 Score = 218 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 63/286 (22%), Positives = 102/286 (35%), Gaps = 50/286 (17%) Query: 14 SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 73 A +A++AG ++R + + ++ ++ K+ DL T D+ + + SS+ K+P + IG Sbjct: 11 YAVILARQAGEMIREAL-KNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIG 69 Query: 74 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNV 133 EE + + E E W +DP+DGT + V Sbjct: 70 EESVAAGE-KTVFTEQPTW----------------------VIDPIDGTTNFVH-RFPFV 105 Query: 134 TVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIIT 193 V IG + G++ V + G G GAF K + + IT Sbjct: 106 AVSIGFLVNKEMEFGIVYS----------CVEDKMYTGRKGKGAFCNGQKLQVSQQEDIT 155 Query: 194 -----TTRSHSNKLVTDCVAAMNPD--------AVLRVGGAGNKIIQLIEGKASAYVFAS 240 T S K T + N + + VG A + + G A AY Sbjct: 156 KSLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMG 215 Query: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLA 286 C WD +I+ GG L D+ G ++ LA Sbjct: 216 IHC--WDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLA 259 >1IMD-A nrPDB Length = 277 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 66/286 (23%), Positives = 104/286 (36%), Gaps = 50/286 (17%) Query: 14 SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 73 A ++A++AG +V I + ++ ++ K+ DL T D+ + + SS+ K+P + IG Sbjct: 11 YAVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIG 69 Query: 74 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNV 133 EE + + E L ++ W +DP+DGT + V Sbjct: 70 EESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVH-RFPFV 105 Query: 134 TVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIIT 193 V IG A K GV+ V G+ G GAF K + + IT Sbjct: 106 AVSIGFAVNKKIEFGVVYS----------CVEGKMYTARKGKGAFCNGQKLQVSQQEDIT 155 Query: 194 -----TTRSHSNKLVTDCVAAMNPD--------AVLRVGGAGNKIIQLIEGKASAYVFAS 240 T S T + N + + VG A + + G A AY Sbjct: 156 KSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMG 215 Query: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLA 286 C WD +I+ GG L D+ G + +LA Sbjct: 216 IHC--WDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILA 259 >2BJI-A nrPDB Length = 277 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 65/286 (22%), Positives = 104/286 (36%), Gaps = 50/286 (17%) Query: 14 SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 73 A ++A +AG +VR + + ++ I+ K+ DL T D+ + + +S+ K+P + IG Sbjct: 11 YAVTLAGQAGEVVREAL-KNEMNIMVKSSPADLVTATDQKVEKMLITSIKEKYPSHSFIG 69 Query: 74 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNV 133 EE + + E L ++ W +DP+DGT + G V Sbjct: 70 EESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVHG-FPFV 105 Query: 134 TVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIIT 193 V IG K G++ + + G G GAF K + + IT Sbjct: 106 AVSIGFVVNKKMEFGIVYS----------CLEDKMYTGRKGKGAFCNGQKLQVSHQEDIT 155 Query: 194 -----TTRSHSNKLVTDCVAAMNPDA--------VLRVGGAGNKIIQLIEGKASAYVFAS 240 T S T + N + + VG A + + G A AY Sbjct: 156 KSLLVTELGSSRTPETVRIILSNIERLLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMG 215 Query: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLA 286 C WD +I+ GG L D+ G +S LA Sbjct: 216 IHC--WDVAGAGIIVTEAGGVLLDVTGGPFDLMSRRVIASSNKTLA 259 >5J16-A nrPDB Length = 283 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 61/267 (22%), Positives = 106/267 (39%), Gaps = 41/267 (15%) Query: 9 MRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPK 68 M L A + Q+AG+ +++++ E +L I K+ DL T D+ + I ++ +P Sbjct: 9 MALYGFAQGLIQEAGIRIKQLM-EQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPN 67 Query: 69 LTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVW-VDPLDGTKEYTE 127 ++GEE I VW VDP+DGT + Sbjct: 68 HQVLGEE--------------------------GHGHDIDTSKGTVWVVDPIDGTLNFVH 101 Query: 128 GLLDNVTVLIGIAYEGKAIAGVINQPY----YNYEAGPDAVLGRTIWGVLGLGAFGFQLK 183 +N + IGI +GK AG + Y+ + G A G L L+ Sbjct: 102 -QQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLN----DSNLR 156 Query: 184 EVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGC 243 + G + T+ ++ + V + + G A +I+ + G AY+ +P Sbjct: 157 QSIIGINPNWLTKPILGEIFKEIVN--DSRSARAYGSAALEIVSVATGNLEAYM--TPRL 212 Query: 244 KKWDTCAPEVILHAVGGKLTDIHGNVL 270 + WD VIL+ V G+ +++ G L Sbjct: 213 QPWDFAGGLVILYEVNGQASNLLGEPL 239 >4QXD-A nrPDB Length = 293 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 82/284 (28%), Positives = 129/284 (45%), Gaps = 25/284 (8%) Query: 5 NTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLAR 64 T L + ++A + + E + I K+ ++ T+ D +Q I S + Sbjct: 2 QTSLFEFANVLITAVKEASYSISKFKEEVE--IKYKSDGSE-VTQVDTQSQQIIFSIIKN 58 Query: 65 KFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPS-QYSAIKEEDLVVWVDPLDGTK 123 K+P + IIGEED+ + I D+Q I + S + I D++++VDPLDGT Sbjct: 59 KYPTINIIGEEDV------ENGIPDNQLPTITQLSFGSLENKIININDIIIYVDPLDGTD 112 Query: 124 EYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLK 183 YT D+V VL+G+ Y+GK + G++++P+YN E + + + Sbjct: 113 CYTHKQYDSVCVLVGVTYKGKPMIGIVSKPFYNNEI------------TFAIENYISSIS 160 Query: 184 EVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGC 243 P II S N + + +P V GG+G K++ +I +A Y Sbjct: 161 LQPLNDKIIFVC-SKKNDIQHLIKSFPDPYEVKYKGGSGAKMMAIIHQEADIYYHPLIQS 219 Query: 244 KKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSA--GVL 285 WDT A +VIL A GG + DI+GN L Y K GVL Sbjct: 220 CTWDTLAAQVILEAQGGIVCDIYGNPLCYPSSKKESMRHKKGVL 263 >2CZH-A nrPDB Length = 299 Score = 200 bits (509), Expect = 4e-52, Method: Composition-based stats. Identities = 68/273 (24%), Positives = 94/273 (34%), Gaps = 50/273 (18%) Query: 12 VASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTI 71 +A +A +AG I+R+ + E + + KT A DL T+ D L + I S L +FP Sbjct: 31 FQAAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRF 89 Query: 72 IGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLD 131 I EE S C +S +DP+DGT + Sbjct: 90 IAEEAAASG-----------------AKCVLTHSP------TWIIDPIDGTCNFVH-RFP 125 Query: 132 NVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLK-----EVP 186 V V IG A + GVI R G G GAF + E Sbjct: 126 TVAVSIGFAVRQELEFGVIY----------HCTEERLYTGRRGRGAFCNGQRLRVSGETD 175 Query: 187 AGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNK--------IIQLIEGKASAYVF 238 K ++ T T + N + +L G + + L G A AY Sbjct: 176 LSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQ 235 Query: 239 ASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQ 271 C WD A VI+ GG + D G L Sbjct: 236 FGLHC--WDLAAATVIIREAGGIVIDTSGGPLD 266 >6IB8-A nrPDB Length = 271 Score = 190 bits (481), Expect = 8e-49, Method: Composition-based stats. Identities = 58/261 (22%), Positives = 93/261 (35%), Gaps = 42/261 (16%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A A+KAG ++ + D + + D T D+ A+ I ++ + +P+ TII E Sbjct: 12 AVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITE 71 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E E DQ D+ +DPLDGT + + L + Sbjct: 72 ESGELEGTDQ--------------------------DVQWVIDPLDGTTNFIK-RLPHFA 104 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQL-------KEVPA 187 V I + +G+ V+ P N G + G G+ L Sbjct: 105 VSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK 164 Query: 188 GKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWD 247 K TT + KL +C R G A + + G+ F G + WD Sbjct: 165 AKQYATTYINIVGKLFNECA------DFRRTGSAALDLAYVAAGRVDG--FFEIGLRPWD 216 Query: 248 TCAPEVILHAVGGKLTDIHGN 268 A E+++ GG ++D G Sbjct: 217 FAAGELLVREAGGIVSDFTGG 237 >5ZHH-A nrPDB Length = 270 Score = 189 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 55/261 (21%), Positives = 88/261 (33%), Gaps = 30/261 (11%) Query: 25 IVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQ 84 +++ + + + I EK DL T AD+ ++ + + R FP+ +I+ EE D Sbjct: 21 VLQGYLGKLEDAITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGNQDN 80 Query: 85 ELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGK 144 E + +DPLDGT Y V IG+ G Sbjct: 81 EYL--------------------------WAIDPLDGTTNYAH-QYPAFCVSIGLLINGV 113 Query: 145 AIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTR-SHSNKLV 203 GVI P+++ A LG T + +L + R + N Sbjct: 114 PQVGVIYDPFHDELFRGAAGLGATRNRRPIKVSDTSELSKSLLVTGFAYDRRETPDNNYA 173 Query: 204 TDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLT 263 C V R G A + + G+ Y G WD A ++L GGK+T Sbjct: 174 EFCHLTHLTQGVRRSGSAALDLAHVACGRVDGY--WERGISPWDVVAGVILLEEAGGKVT 231 Query: 264 DIHGNVLQYHKDVKHMNSAGV 284 L+ + + Sbjct: 232 AYDSTPLKIATGRILATNGSI 252 >4O7I-A nrPDB Length = 325 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 63/304 (20%), Positives = 108/304 (35%), Gaps = 41/304 (13%) Query: 12 VASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTI 71 +A A I Q + I V + T D Q + + FP+ I Sbjct: 7 LALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPVTVGDYSVQAYVNKKIHETFPEDQI 66 Query: 72 IGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLV------VWVDPLDGTKEY 125 + EED + D + +I + +DP+DGT + Sbjct: 67 VAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDPIDGTLGF 126 Query: 126 TEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEV 185 + V + +G GV+ P N+E G + G GA F + ++ Sbjct: 127 L--RREQYAVCLAFMIDGDIKVGVLGCP--NFEG------GLIVAAQKGCGAKMFSVNDI 176 Query: 186 PAGK--HIITTTRSHS----------------NKLVTDCVAAMNPDAVLRVGGAGNKIIQ 227 GK H+ TT ++ +K +T+ + P + + K + Sbjct: 177 KNGKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRM---DSQCKYMA 233 Query: 228 LIEGKASAYVFASPGC----KKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAG 283 + G+A Y+ K WD A +I+ GGK+TDI+GN L + N+ G Sbjct: 234 IASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHG 293 Query: 284 VLAT 287 ++A+ Sbjct: 294 IVAS 297 >1INP-A nrPDB Length = 400 Score = 177 bits (447), Expect = 7e-45, Method: Composition-based stats. Identities = 79/315 (25%), Positives = 119/315 (37%), Gaps = 74/315 (23%) Query: 43 ATDLQTKADRLAQMSICSSLARKFPKLT--IIGEED---------------LPSEE---- 81 A D +T AD L Q I ++ KFP L I GEE P+EE Sbjct: 46 AVDFKTLADVLVQEVIKENMENKFPGLGKKIFGEESNELTNDLGEKIIMRLGPTEEETVA 105 Query: 82 -----------VDQELIEDSQWEEILKQPC-PSQYSAIKEEDLVVWVDPLDGTKEYTEGL 129 + L + + P S I ++ L +WVDP+D T +Y +G Sbjct: 106 LLSKVLNGNKLASEALAKVVHQDVFFSDPALDSVEINIPQDILGIWVDPIDSTYQYIKGS 165 Query: 130 LD-------------NVTVLIGI--AYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLG 174 D VTVLIG+ G + GVINQP+ + + G+ WG+ Sbjct: 166 ADITPNQGIFPSGLQCVTVLIGVYDIQTGVPLMGVINQPFVSQDLHTRRWKGQCYWGLSY 225 Query: 175 LG-------------------AFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAV 215 LG + G Q + + + ++ + + + Sbjct: 226 LGTNIHSLLPPVSTRSNSEAQSQGTQNPSSEGSCRFSVVISTSEKETIKGALSHVCGERI 285 Query: 216 LRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTD----IHGNV-- 269 R GAG K + +I G A Y+F+ KWD+CA IL A+GG + D + N Sbjct: 286 FRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMGGGMVDLKECLERNPDT 345 Query: 270 -LQYHKDVKHMNSAG 283 L + V H+ + G Sbjct: 346 GLDLPQLVYHVGNEG 360 >2PCR-A nrPDB Length = 264 Score = 173 bits (437), Expect = 9e-44, Method: Composition-based stats. Identities = 55/274 (20%), Positives = 98/274 (35%), Gaps = 52/274 (18%) Query: 8 LMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFP 67 L + + A A G +++ + +E+ D + D+ ++ I + + FP Sbjct: 4 LKKYLEVAKIAALAGGQVLKENFGKVKKENIEEKGEKDFVSYVDKTSEERIKEVILKFFP 63 Query: 68 KLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTE 127 ++GEE + ++DPLDGTK Y Sbjct: 64 DHEVVGEEMGAEGSGSE---------------------------YRWFIDPLDGTKNYIN 96 Query: 128 GLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF----GFQLK 183 G V +G+ + I G + PY++ + WG GLGA+ ++K Sbjct: 97 G-FPIFAVSVGLVKGEEPIVGAVYLPYFD----------KLYWGAKGLGAYVNGKRIKVK 145 Query: 184 EVPAGKH--IITTTRSHSNKLVTDCVAAMNP-----DAVLRVGGAGNKIIQLIEGKASAY 236 + + KH ++ S S + ++ + ++ R G A + + EG Sbjct: 146 DNESLKHAGVVYGFPSRSRRDISIYLNIFKDVFYEVGSMRRPGAAAVDLCMVAEGIFDGM 205 Query: 237 VFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVL 270 + K WD A VIL GG T + G Sbjct: 206 MEFE--MKPWDITAGLVILKEAGGVYT-LVGEPF 236 >5YHT-A nrPDB Length = 267 Score = 164 bits (414), Expect = 5e-41, Method: Composition-based stats. Identities = 65/275 (23%), Positives = 98/275 (35%), Gaps = 54/275 (19%) Query: 4 SNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLA 63 S+ LM A ++A +A + R DL I K T T ADR + + +L Sbjct: 9 SHDDLM----LALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLG 63 Query: 64 RKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTK 123 R P ++GEE S QW VDP+DGTK Sbjct: 64 RDRPGDGVLGEEFGGSTT-----FTGRQW----------------------IVDPIDGTK 96 Query: 124 EYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLK 183 + G+ LI + +G GV++ P L R W G GAF Sbjct: 97 NFVRGV-PVWASLIALLEDGVPSVGVVSAP----------ALQRRWWAARGRGAFASVDG 145 Query: 184 EVPAGKHIITTTRSHSNKLVTDCVAAMN-----------PDAVLRVGGAGNKIIQLIEGK 232 P + + HS L ++ D V RV G+ + + + Sbjct: 146 ARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAE 205 Query: 233 ASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHG 267 + + A P WD A ++++ GG+LT + G Sbjct: 206 GAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDG 240 >2P3V-A nrPDB Length = 256 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 53/265 (20%), Positives = 92/265 (34%), Gaps = 50/265 (18%) Query: 9 MRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPK 68 M + + + +K G ++ D + +KT D+ T+ DR AQ I + + FP Sbjct: 1 MDRLDFSIKLLRKVGHLLMIHWGRVD-NVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPD 59 Query: 69 LTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTE 127 I+ EE I E+ +W+ DP+DGT + Sbjct: 60 ENIMAEE------------------------------GIFEKGDRLWIIDPIDGTINFVH 89 Query: 128 GLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPA 187 G L N ++ + G+ GV++ P L T++ G GAF + + Sbjct: 90 G-LPNFSISLAYVENGEVKLGVVHAP----------ALNETLYAEEGSGAFFNGERIRVS 138 Query: 188 GKHIITTTRSHSNKLVTDCVAAMN-----PDAVLRVGGAGNKIIQLIEGKASAYVFASPG 242 + + V + + +G A + G+ F + Sbjct: 139 ENASLEECVGSTGSYVDFTGKFIERMEKRTRRIRILGSAALNAAYVGAGRVD--FFVTWR 196 Query: 243 CKKWDTCAPEVILHAVGGKLTDIHG 267 WD A +I+ GG +TD G Sbjct: 197 INPWDIAAGLIIVKEAGGMVTDFSG 221 >3LV0-A nrPDB Length = 267 Score = 157 bits (395), Expect = 9e-39, Method: Composition-based stats. Identities = 61/264 (23%), Positives = 93/264 (35%), Gaps = 50/264 (18%) Query: 16 YSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEE 75 A KAG + R E V D ++ADR A+ I + L++ PK + EE Sbjct: 15 VQAAMKAGRSLVRDYGEVQNLQVSLKGPADYVSQADRKAEKIIFNELSKARPKFGFLMEE 74 Query: 76 DLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTV 135 ++ + EDSQ I VDPLDGT + G + V Sbjct: 75 S------EEIIGEDSQHRFI--------------------VDPLDGTTNFLHG-IPFFAV 107 Query: 136 LIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKH----- 190 I + +GK +AGVI P + G GAF + + + Sbjct: 108 SIALESQGKIVAGVIYNPIND----------ELFTAERGSGAFFNDRRCRVSARRRLEDC 157 Query: 191 IITTTRSHSNK------LVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCK 244 +I T H + L+ + R G A + + G+ F + Sbjct: 158 VIATGMPHLGRPGHGTYLIELRNVMAEVSGIRRFGTAALDLAYVAAGRTDG--FWEDNLQ 215 Query: 245 KWDTCAPEVILHAVGGKLTDIHGN 268 WD A +++ GG +TD G Sbjct: 216 IWDMAAGILMVREAGGFVTDKEGG 239 >5DJK-A nrPDB Length = 288 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 51/233 (21%), Positives = 80/233 (34%), Gaps = 48/233 (20%) Query: 49 KADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIK 108 DR A + L + P ++ EE A Sbjct: 69 AGDRQANSLLLRRLQAERPGDAVLSEEA-------------------------HDDLARL 103 Query: 109 EEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVL--- 165 + D V +DPLDGT+E++ D+ V I + I A + V Sbjct: 104 KSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTD 163 Query: 166 ----GRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGA 221 G GV G PA H I T + + +G A Sbjct: 164 TVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQP---------------VSIGSA 208 Query: 222 GNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHK 274 G K + +I+G AY+ A G +WD+ AP ++ A G + + G+ L+Y++ Sbjct: 209 GAKAMAVIDGYVDAYLHAG-GQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQ 260 >5EQA-A nrPDB Length = 277 Score = 131 bits (328), Expect = 4e-31, Method: Composition-based stats. Identities = 55/261 (21%), Positives = 89/261 (34%), Gaps = 36/261 (13%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A A AG ++R+ + + I+ K + T AD+ A+ ++ S + FP + GE Sbjct: 21 ANKAANAAGDVIRKYFRKNNFDIIHKNDLSP-VTIADQSAEEAMVSVILDNFPSHAVYGE 79 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E + D D V +DP+DGTK + G Sbjct: 80 EKGWRCKQDSA-------------------------DYVWVLDPIDGTKSFITG-KPLFG 113 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 194 LI + G I G+I+QP T+ G L + + T Sbjct: 114 TLIALLQNGTPILGIIDQPVLKERWIGITGKRTTLNGQEVSTRTCADLSQA-----YLYT 168 Query: 195 TRSH--SNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPE 252 T H S + + + G L G + G K +D A Sbjct: 169 TSPHLFSGDAEEAFIRVRDKVKIPLYGCDCYAYALLSSGFVD--LVVESGLKPYDFLALI 226 Query: 253 VILHAVGGKLTDIHGNVLQYH 273 ++ GG +TD G+ L++ Sbjct: 227 PVIEGSGGVITDWKGHQLRWE 247 >1KA0-A nrPDB Length = 357 Score = 129 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 65/329 (19%), Positives = 108/329 (32%), Gaps = 60/329 (18%) Query: 15 AYSIAQKAGMIVRR----VIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLT 70 A +KA ++ +R VI+ D + K + T D AQ I +++ FP Sbjct: 10 ATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSP-VTTGDYAAQTIIINAIKSNFPDDK 68 Query: 71 IIGEEDLPS-----------------EEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLV 113 ++GEE E ++ +D + P S + D Sbjct: 69 VVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFG 128 Query: 114 ----------VWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQP------YYNY 157 +DP+DGTK + G + V + + +G G I P Y Sbjct: 129 NYEGGRKGRFWCLDPIDGTKGFLRG--EQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQ 186 Query: 158 EAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDC-----VAAMNP 212 + G V GLGAF + + I + ++T ++ + Sbjct: 187 DLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDE 246 Query: 213 DAVLRVG---------GAGNKIIQLIEGKASAYVFASPGC----KKWDTCAPEVILHAVG 259 ++ + K L G A Y+ K WD A VI+H G Sbjct: 247 QTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAG 306 Query: 260 GKLTD-IHGNVLQYHKDVKHMNSAGVLAT 287 G TD + L + + GV+A+ Sbjct: 307 GIHTDAMEDVPLDFGNGRTLA-TKGVIAS 334 >5ESY-A nrPDB Length = 346 Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 49/304 (16%), Positives = 88/304 (28%), Gaps = 55/304 (18%) Query: 34 DLGIVEKTCATDLQTKADRLAQMSICSSLARKFPK--LTIIGEEDLP------------- 78 + K+ + T AD +Q + L ++ +++ EED Sbjct: 30 QSDVQSKSDKSP-VTVADYGSQAVVSLVLEKELSSEPFSLVAEEDSGDLRKDGSQDTLER 88 Query: 79 ---------SEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGL 129 + E S + + C + +DP+DGTK + G Sbjct: 89 ITKLVNDTLATEESFNGSTLSTDDLLRAIDCGTSEGG--PNGRHWVLDPIDGTKGFLRG- 145 Query: 130 LDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGF--------- 180 D V +G+ EGK + GV+ P + ++ +G F Sbjct: 146 -DQYAVALGLLEEGKVVLGVLACPNLPLASIAGNNKNKSSSDEIGCLFFATIGSGTYMQL 204 Query: 181 -QLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGG-------------AGNKII 226 K P + + A + + + K Sbjct: 205 LDSKSSPVKVQVSSVENPEEASFFESFEGAHSLHDLSSSIANKLGVKAPPVRIDSQAKYG 264 Query: 227 QLIEGKASAYV---FASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAG 283 L G + Y+ K WD A +++ GG +TD G L + K G Sbjct: 265 ALSRGDGAIYLRFPHKGYREKIWDHVAGAIVVTEAGGIVTDAAGKPLDFSKGKYLDLDTG 324 Query: 284 VLAT 287 ++ Sbjct: 325 IIVA 328 >4N81-A nrPDB Length = 259 Score = 99.3 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 59/264 (22%), Positives = 94/264 (35%), Gaps = 45/264 (17%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74 A+ +A A I+R L I K + TKADR A+ ++ + L ++ P+ I GE Sbjct: 13 AHRLADVAADIIRPFFRAP-LTIDLKADHSP-VTKADRGAEQAMRAILEQERPEDGIFGE 70 Query: 75 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134 E S + L +DP+DGT+ + G + Sbjct: 71 EMGVSRPDARRL---------------------------WVLDPIDGTRAFI-GGRASFG 102 Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 194 LI + +G+ + G+INQP + L + G + PA H + Sbjct: 103 TLIALVEDGRPVLGIINQPIHQERWVGVKDLPTSFNGE------VIHTRSCPALDHALLA 156 Query: 195 TRSH-----SNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTC 249 T S ++ D + D +L GG L G + G K +D Sbjct: 157 TTSPWLFEKEGEVHFDKIRLKCRDTLL--GGDCYNYGLLSLGHCD--LVVEQGLKFYDFA 212 Query: 250 APEVILHAVGGKLTDIHGNVLQYH 273 A I+ GG + D L + Sbjct: 213 ALVPIVEGAGGIMRDWQNRPLNKN 236 >2Q74-A nrPDB Length = 299 Score = 96.6 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 48/269 (17%), Positives = 82/269 (30%), Gaps = 51/269 (18%) Query: 31 AEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDS 90 +GD + K+ TD T D + + LA+ P I+GEE +V Sbjct: 40 GDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADV-------- 91 Query: 91 QWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVI 150 +A + + +DP+DGT + G + V IG G +AG + Sbjct: 92 --------------TATPSDRVTWVLDPIDGTVNFVYG-IPAYAVSIGAQVGGITVAGAV 136 Query: 151 NQPYYNYEAGPDAVLGRTIWGVLGLGAFG----FQLKEVPAGKHIITTTRSHSNKLVTDC 206 LG + G +L G + R + Sbjct: 137 ADVAARTVYSAATGLGAHLTDERGRHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLA 196 Query: 207 VAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTC----------------- 249 V R+G A + + G+ AY G + WD Sbjct: 197 HVVPLVRDVRRIGSAALDLCMVAAGRLDAYY--EHGVQVWDCAAGALIAAEAGARVLLST 254 Query: 250 -----APEVILHAVGGKLTDIHGNVLQYH 273 A V++ A G ++ + +++ Sbjct: 255 PRAGGAGLVVVAAAPGIADELLAALQRFN 283 >3B8B-A nrPDB Length = 292 Score = 91.2 bits (224), Expect = 5e-19, Method: Composition-based stats. Identities = 68/281 (24%), Positives = 100/281 (35%), Gaps = 48/281 (17%) Query: 14 SAYSIAQKAGMIVRRVIA--EGDLGIVEKTCATDLQTKADRLAQMSICSSLARK-FPKLT 70 +A A KAG + + + D I K + L T ADR A +I + L FP Sbjct: 26 AAIDAALKAGEKILSIYEDPKSDFEIERKADNSPL-TIADRKAHEAIVAILNETPFP--- 81 Query: 71 IIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLL 130 ++ EE + W+ + VDPLDGTKE+ + Sbjct: 82 VLSEE-----GKHMDYAVRRGWDTL------------------WIVDPLDGTKEFIKRNG 118 Query: 131 DNVTVLIGIAYEGKAIAGVINQP----YYNYEAGPDAVLGRTIWGVLGLGAFGFQ----- 181 + TV I + + GVI P Y G A I G+ G Q Sbjct: 119 E-FTVNIALVQNAVPVMGVIYVPVKKELYFAVEGTGAYKCSGIVGLEDEGVTLQQMIEKS 177 Query: 182 --LKEVPAGKHIITTTRSHSNKLVTDC----VAAMNPDAVLRVGGAGNKIIQLIEGKASA 235 + A H I T+ + + + L G+ KI + EGKA Sbjct: 178 ERMPLADARDHFIAVASRSHLTPETETYIADLKKKHGNVELISSGSSIKICLVAEGKADV 237 Query: 236 YVFASPGCKKWDTCAPEVILHAVGGKLTDI-HGNVLQYHKD 275 Y +P +WDT A I A G ++ L+Y+K+ Sbjct: 238 YPRFAPTM-EWDTAAGHAIARAAGMEVYQAGKEEPLRYNKE 277 >3QMF-A nrPDB Length = 273 Score = 89.6 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 48/246 (19%), Positives = 88/246 (35%), Gaps = 42/246 (17%) Query: 34 DLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWE 93 ++ K DL T D+ Q LA FP+ ++ EE Sbjct: 38 EMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEE------------------ 79 Query: 94 EILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQP 153 S E + + +DP+DGT + ++ +++ YEGK + + Sbjct: 80 -------KSNAMITNEINHLWIMDPIDGTANLVK-QQEDYCIILAYFYEGKPMLSYVYDY 131 Query: 154 YYNYEAGPDAVLGRTIWGVLGLGAFGFQLK--EVPAGK--HIITTTRSHSNKLVTDCVAA 209 + + + G GAF +K E P+ K I + + L T Sbjct: 132 PHK----------KLYKAIRGEGAFCNGIKMEEPPSLKLEDAIISFNAQVMNLDTVQDLF 181 Query: 210 MNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNV 269 + VG G +++ +G+ A++ +P K WD A + + K+T + G Sbjct: 182 DASFSYRLVGACGLDSMRVAKGQFGAHINTNP--KPWDIAAQFLFAELLNLKMTTLDGKA 239 Query: 270 LQYHKD 275 + + K Sbjct: 240 IDHLKG 245 >1VDW-A nrPDB Length = 254 Score = 89.6 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 67/201 (33%), Gaps = 17/201 (8%) Query: 73 GEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDN 132 G+E ++V + +I + + + D V VDPLDG+ + G + Sbjct: 40 GDETKVVDKVAENIIISKFKDLGVNVVSEEIGRIDQGSDYTVVVDPLDGSYNFING-IPF 98 Query: 133 VTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLKEVPAGKH 190 V + I +E I I +P R G+ G G++ G ++K + Sbjct: 99 FAVSVAIFHEKDPIYAFIYEPIVE----------RLYEGIPGKGSYLNGEKIKVRELAEK 148 Query: 191 IITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCA 250 + + +G ++ L G A V + D A Sbjct: 149 PSISFYTKGKGT----KIIDKVKRTRTLGAIALELAYLARGALDAVVDIRNYLRPTDIAA 204 Query: 251 PEVILHAVGGKLTDIHGNVLQ 271 VI G + D+ G ++ Sbjct: 205 GVVIAREAGAIVKDLDGKDVE 225 >1XI6-A nrPDB Length = 262 Score = 86.9 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 52/285 (18%), Positives = 89/285 (31%), Gaps = 56/285 (19%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEKTCAT-DLQTKADRLAQMSICSSLARKFPKLTIIG 73 A I + D G + K + D D+LA+ I S + + ++ Sbjct: 18 AIDIISDFETTIMPFFGNPDGGKLVKISPSGDETKLVDKLAEDLILSRITEL--GVNVVS 75 Query: 74 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNV 133 EE E + V VDPLDG+ + G + Sbjct: 76 EE---------------------------VGVIDNESEYTVIVDPLDGSYNFIAG-IPFF 107 Query: 134 TVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF----GFQLKEVPAGK 189 + + + + K I +I +P R G+ G GAF ++++ P K Sbjct: 108 ALSLAVFKKDKPIYAIIYEPMTE----------RFFEGIPGEGAFLNGKRIKVRKTPDEK 157 Query: 190 HIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTC 249 I+ + V + +G ++ L G V + D Sbjct: 158 PSISFYSRGKG---HEIVKHVK--RTRTLGAIALELAYLAMGALDGVVDVRKYVRPTDIA 212 Query: 250 APEVILHAVGGKLTDIHGNVLQYH------KDVKHMNSAGVLATL 288 A +I G + D G + DV +NS +L T+ Sbjct: 213 AGTIIAKEAGALIKDSAGKDIDISFNATDRLDVIAVNSEELLKTI 257 >1G0H-A nrPDB Length = 252 Score = 84.6 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 40/263 (15%), Positives = 85/263 (32%), Gaps = 44/263 (16%) Query: 18 IAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKA-DRLAQMSICSSLARKFPKLTIIGEED 76 IA++ + D V T + +T+ D++++ L + I+ EE Sbjct: 10 IAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSL--NVNIVSEEL 67 Query: 77 LPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVL 136 + + V +DP+DG+ + G + Sbjct: 68 GVIDNSSE---------------------------WTVVIDPIDGSFNFING-IPFFAFC 99 Query: 137 IGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLKEVPAGKHIITT 194 G+ + G+ + + G GA+ G ++K + I Sbjct: 100 FGVFKNNEPYYGLTYE----------FLTKSFYEAYKGKGAYLNGRKIKVKDFNPNNIVI 149 Query: 195 TRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVI 254 + S K+ + + V G G ++ + +G A P + D + +I Sbjct: 150 SYYPSKKIDLEKLRN-KVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYII 208 Query: 255 LHAVGGKLTDIHGNVLQYHKDVK 277 G +TD +G+ L++ + Sbjct: 209 CKEAGALITDENGDELKFDLNAT 231 >1LBZ-A nrPDB Length = 252 Score = 68.1 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 50/263 (19%), Positives = 90/263 (34%), Gaps = 52/263 (19%) Query: 15 AYSIAQKAGMIVRRVIAEGDLGIVEK-----TCATDLQTKADRLAQMSICSSLARKFPKL 69 A I+++ VR+ IA L K T + ADR+A+ + L ++ + Sbjct: 6 ALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTK-AADRVAEDAALEILRKER--V 62 Query: 70 TIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGL 129 T++ EE E D+ V +DPLDGT T G Sbjct: 63 TVVTEESGVLGEG----------------------------DVFVALDPLDGTFNATRG- 93 Query: 130 LDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGK 189 + +V + +Y K ++ Y + G + GA+ + Sbjct: 94 IPVYSVSLCFSYSDKLK-----DAFFGY--VYNLATGDEYYA-DSSGAYRNGER-----I 140 Query: 190 HIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPG--CKKWD 247 + + N ++ + G A ++ +G ++ PG + +D Sbjct: 141 EVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYD 200 Query: 248 TCAPEVILHAVGGKLTDIHGNVL 270 A I GGK+T++ G L Sbjct: 201 AAAGVFIAEKAGGKVTELDGESL 223 >3OBY-A nrPDB Length = 352 Score = 29.5 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 39/119 (32%), Gaps = 12/119 (10%) Query: 177 AFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVG------GAGNKIIQLIE 230 F LK K + + + + + + + G + I+++ Sbjct: 227 GFIEILKRRVVDKIVGEVRLAEEAEYIDRLLEGIAKGERVAYGLDEVREAHNYRAIEVLL 286 Query: 231 GKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLR 289 A ++ +KWD + GGK+ + + + M+ G+ A LR Sbjct: 287 -VADEFLLEER--EKWDVDGLLREVEESGGKVVIMSTE---FEPGKRLMSLGGIAALLR 339 >3C94-A nrPDB Length = 482 Score = 29.1 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 32/90 (35%), Gaps = 15/90 (16%) Query: 4 SNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDL----QTKADRLAQMSIC 59 S+ V +L +S A +A + IV +T +L T D+ + + Sbjct: 360 SDNVDAQLYNGFFSDADRAA-----------MKIVLETEPRNLPALDITFVDKRIEKLLF 408 Query: 60 SSLARKFPKLTIIGEEDLPSEEVDQELIED 89 + AR FP E+ E Q + Sbjct: 409 NYRARNFPGTLDYAEQQRWLEHRRQVFTPE 438 >3ZIF-A nrPDB Length = 911 Score = 29.1 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 23/133 (17%), Positives = 38/133 (28%), Gaps = 15/133 (11%) Query: 165 LGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDA-------VLR 217 + T + + G G K + +S N +P V Sbjct: 96 MASTYFDIRGTLDRGASFKPYSGTAYNSFAPKSAPNNTQFRQANNGHPAQTIAQASYVAT 155 Query: 218 VGGAGNKI-IQLIEGKASAY----VFASPGCKK--WDTCAPEVILHAVGGKLTDIHGNVL 270 +GGA N + + + E + Y P W T ++ GG++ Sbjct: 156 IGGANNDLQMGVDERQLPVYANTTYQPEPQLGIEGW-TAGSMAVIDQAGGRVLRNPTQTP 214 Query: 271 QYHKDVKHMNSAG 283 Y K N G Sbjct: 215 CYGSYAKPTNEHG 227 >5EUA-A nrPDB Length = 265 Score = 28.8 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 37/113 (32%), Gaps = 11/113 (9%) Query: 156 NYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAA--MNPD 213 + EA A +G + G G++ E A T + LV + A NP+ Sbjct: 10 DLEAHNQAKIGVALVSENGNLIQGYRANERFAMCS---TFKLPLAALVLSRIDAGEENPE 66 Query: 214 AVLRVGGAGNKII------QLIEGKASAYVFASPGCKKWDTCAPEVILHAVGG 260 L A + + G + + D A ++L VGG Sbjct: 67 RKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSALQLSDNAAANLLLKEVGG 119 >5HJK-A nrPDB Length = 352 Score = 28.8 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 54/187 (28%), Gaps = 16/187 (8%) Query: 56 MSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVW 115 I S++ + +PK+ +I S +E E L IK + V+ Sbjct: 125 EVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVF 184 Query: 116 VDPLDGTKEYTEGLLDNVTVLIGIAYEGK----AIAGVINQPYYNYEAGPDAVLGRTIWG 171 +P +G + L+ +G+ AGVI P V I Sbjct: 185 FNPR------MKGERYRIAQLVN---DGERILVPFAGVIPYPLVIARFKNVEVYAVEINE 235 Query: 172 VLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEG 231 A + + + + N D V+ G + L Sbjct: 236 FAVKLA---EENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLS 292 Query: 232 KASAYVF 238 KA ++ Sbjct: 293 KAEKFLH 299 >3GOC-A nrPDB Length = 237 Score = 28.4 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 36/119 (30%), Gaps = 6/119 (5%) Query: 120 DGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFG 179 DG + +G+ G GV P+ P A G + G G Sbjct: 114 DG-YGVAHPRRFGLASHLGVL-TGLPTIGVAKNPFTFSYEDPGAPRGSAAPLLAGADEVG 171 Query: 180 FQLKEVPAGKHIITTTRSHSNKLVTDC---VAAMNPDAVLRVGGAGNKIIQLIEGKASA 235 L+ +G + + H L C +A + + + + +A+A Sbjct: 172 RALRTQ-SGVKPVFVSVGHRVDLDHACAHTLALTPKYRIPETTRRADSLCRRALKEATA 229 >1IYW-A nrPDB Length = 862 Score = 28.4 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 37/129 (28%), Gaps = 16/129 (12%) Query: 17 SIAQKAGMIV----RRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTII 72 +A +A +V R DL + + L T + +A P+ T+ Sbjct: 164 GLAYRAPRLVNWCPRCETTLSDLEVETEPTPGKLYTLR-YEVEGGGFIEIATVRPE-TVF 221 Query: 73 GEEDLPSEEVDQELIEDSQ----------WEEILKQPCPSQYSAIKEEDLVVWVDPLDGT 122 ++ + D+ W IL P + + DPLD Sbjct: 222 ADQAIAVHPEDERYRHLLGKRARIPLTEVWIPILADPAVEKDFGTGALKVTPAHDPLDYE 281 Query: 123 KEYTEGLLD 131 GL Sbjct: 282 IGERHGLKP 290 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.111 0.279 Lambda K H 0.267 0.0345 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,837,157 Number of Sequences: 36641 Number of extensions: 372766 Number of successful extensions: 1272 Number of sequences better than 10.0: 37 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1101 Number of HSP's gapped (non-prelim): 87 length of query: 308 length of database: 10,336,785 effective HSP length: 97 effective length of query: 211 effective length of database: 6,782,608 effective search space: 1431130288 effective search space used: 1431130288 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.2 bits)