BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O95843 (209 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2GGZ-A nrPDB 430 e-121 2R2I-A nrPDB 200 3e-52 2NA0-A nrPDB 197 4e-51 1JBA-A nrPDB 130 5e-31 5T7C-A nrPDB 122 1e-28 1BJF-A nrPDB 120 3e-28 5M6C-E nrPDB 115 1e-26 2I94-A nrPDB 99 2e-21 2LCP-A nrPDB 98 3e-21 2D8N-A nrPDB 97 4e-21 2L2E-A nrPDB 97 5e-21 1S1E-A nrPDB 94 3e-20 1S6C-A nrPDB 94 4e-20 6EPA-A nrPDB 91 3e-19 3DD4-A nrPDB 91 5e-19 2JUL-A nrPDB 85 3e-17 2JU0-A nrPDB 74 6e-14 2E6W-A nrPDB 60 7e-10 4RGJ-A nrPDB 58 3e-09 4IL1-A nrPDB 57 5e-09 4ORC-B nrPDB 57 6e-09 4YZB-A nrPDB 57 8e-09 5JN2-A nrPDB 55 3e-08 1JFJ-A nrPDB 54 4e-08 1V1G-A nrPDB 53 8e-08 2ZFD-A nrPDB 53 1e-07 3U0K-A nrPDB 52 1e-07 1UHN-A nrPDB 52 2e-07 4OY4-A nrPDB 52 2e-07 5YPX-A nrPDB 52 2e-07 2JNF-A nrPDB 51 3e-07 3NCG-A nrPDB 50 6e-07 3HZT-A nrPDB 50 6e-07 2N6A-A nrPDB 50 6e-07 3KHE-A nrPDB 50 1e-06 3EK4-A nrPDB 50 1e-06 2F2P-A nrPDB 50 1e-06 6O20-F nrPDB 50 1e-06 3WFN-B nrPDB 49 1e-06 4E53-A nrPDB 49 1e-06 5I0I-E nrPDB 49 1e-06 6HCS-A nrPDB 49 1e-06 2TN4-A nrPDB 49 1e-06 1CLM-A nrPDB 49 2e-06 3LIJ-A nrPDB 49 2e-06 5UKG-A nrPDB 49 2e-06 3Q5I-A nrPDB 48 2e-06 4I2Y-A nrPDB 48 4e-06 3L19-A nrPDB 48 4e-06 2JNX-A nrPDB 47 6e-06 5B8I-B nrPDB 47 8e-06 4MVF-A nrPDB 46 9e-06 3PM8-A nrPDB 46 1e-05 5A2H-A nrPDB 46 1e-05 1GGZ-A nrPDB 45 2e-05 1TOP-A nrPDB 45 3e-05 2AAO-A nrPDB 45 3e-05 3QRX-A nrPDB 45 3e-05 5E37-A nrPDB 44 3e-05 2LM5-A nrPDB 44 4e-05 2M7M-A nrPDB 44 5e-05 1DGU-A nrPDB 44 6e-05 2L1W-A nrPDB 43 9e-05 2AMI-A nrPDB 43 9e-05 3AAJ-A nrPDB 42 1e-04 5E1J-A nrPDB 42 2e-04 5MWC-D nrPDB 40 5e-04 2M29-A nrPDB 40 6e-04 3KF9-A nrPDB 40 7e-04 1DTL-A nrPDB 40 7e-04 4ZCV-A nrPDB 40 0.001 4N5X-A nrPDB 40 0.001 2LAP-A nrPDB 39 0.001 2LHI-A nrPDB 39 0.001 4JWQ-A nrPDB 39 0.001 3K21-A nrPDB 39 0.001 2LMV-A nrPDB 39 0.002 1S6I-A nrPDB 39 0.002 2K7C-A nrPDB 39 0.002 1LKJ-A nrPDB 38 0.002 2LHH-A nrPDB 38 0.002 2NCO-A nrPDB 38 0.003 2K2A-A nrPDB 38 0.003 1FW4-A nrPDB 38 0.003 1C7W-A nrPDB 38 0.003 2LV7-A nrPDB 38 0.003 2B1U-A nrPDB 38 0.003 5Z1Q-A nrPDB 37 0.005 2M97-A nrPDB 37 0.006 1H4B-A nrPDB 37 0.006 2ROB-A nrPDB 37 0.007 5COC-A nrPDB 37 0.007 2KN2-A nrPDB 37 0.007 2GGM-A nrPDB 37 0.008 2HF5-A nrPDB 37 0.009 1JC2-A nrPDB 36 0.009 2OPO-A nrPDB 36 0.011 2OBH-A nrPDB 36 0.012 2G9B-A nrPDB 36 0.013 2KZ2-A nrPDB 36 0.013 2RO9-A nrPDB 35 0.017 3AKA-A nrPDB 35 0.018 2PMY-A nrPDB 35 0.018 1TNP-A nrPDB 35 0.018 2HPS-A nrPDB 35 0.020 3O4Y-A nrPDB 35 0.021 2M5E-A nrPDB 35 0.022 2JOJ-A nrPDB 35 0.022 1F55-A nrPDB 35 0.023 5D43-A nrPDB 35 0.026 4L9M-A nrPDB 35 0.026 1ZMZ-A nrPDB 35 0.026 2KSZ-A nrPDB 35 0.027 3LCP-C nrPDB 35 0.028 5JOJ-A nrPDB 35 0.029 4YGB-B nrPDB 35 0.032 1Q80-A nrPDB 35 0.032 2VRG-A nrPDB 35 0.033 5JOL-A nrPDB 34 0.035 3A4U-B nrPDB 34 0.039 6IIE-A nrPDB 34 0.044 4Q57-A nrPDB 34 0.049 5H7D-E nrPDB 34 0.052 2I18-A nrPDB 34 0.052 2BEC-A nrPDB 34 0.052 1YX7-A nrPDB 34 0.055 2RO8-A nrPDB 33 0.066 5OTJ-D nrPDB 33 0.066 3IFK-A nrPDB 33 0.066 3E3R-A nrPDB 33 0.079 4V3P-LQ nrPDB 33 0.100 4DS7-A nrPDB 33 0.10 3JBH-C nrPDB 32 0.15 2LVK-A nrPDB 32 0.17 5XOP-A nrPDB 32 0.18 4P5W-A nrPDB 32 0.19 1OZS-A nrPDB 32 0.27 4WPX-A nrPDB 31 0.29 3FWC-A nrPDB 31 0.33 5ZOR-A nrPDB 31 0.33 1Y1X-A nrPDB 31 0.34 4I5L-B nrPDB 31 0.40 4MEW-A nrPDB 30 0.67 2E30-A nrPDB 30 0.72 2KQY-A nrPDB 30 0.76 5I2L-A nrPDB 30 0.80 5TBY-E nrPDB 30 0.90 4D1E-A nrPDB 30 0.95 2I08-A nrPDB 30 0.95 4XOX-A nrPDB 30 1.0 2WCE-A nrPDB 30 1.1 5HYD-A nrPDB 29 1.1 1TIZ-A nrPDB 29 1.1 1BU3-A nrPDB 29 1.3 5XND-A nrPDB 29 1.3 1S6J-A nrPDB 29 1.4 1QLS-A nrPDB 29 1.6 5CSF-A nrPDB 29 1.6 5VE9-A nrPDB 29 1.6 2Y5I-A nrPDB 29 1.6 1BOD-A nrPDB 29 1.6 1MO0-A nrPDB 28 2.0 2LUC-A nrPDB 28 2.3 1A75-A nrPDB 28 2.7 4P5X-A nrPDB 28 3.1 1CB1-A nrPDB 28 3.1 5H53-B nrPDB 28 3.3 1TRF-A nrPDB 28 3.4 5Z09-A nrPDB 28 3.5 3MSE-B nrPDB 28 3.7 2KGR-A nrPDB 28 3.7 1ZFS-A nrPDB 28 3.9 2BL0-B nrPDB 28 4.1 4NQG-A nrPDB 27 4.3 1OQP-A nrPDB 27 4.3 4NSC-A nrPDB 27 4.4 6MI5-X nrPDB 27 4.6 2M8U-A nrPDB 27 4.8 3KPX-A nrPDB 27 4.9 1JF0-A nrPDB 27 4.9 1S36-A nrPDB 27 5.2 1NSH-A nrPDB 27 5.6 5US9-A nrPDB 27 5.7 2Q4U-A nrPDB 27 5.8 5CA8-A nrPDB 27 6.3 2MBX-A nrPDB 27 7.1 2MA2-A nrPDB 27 7.1 1M39-A nrPDB 27 7.3 2L0P-A nrPDB 27 7.8 >2GGZ-A nrPDB Length = 211 Score = 430 bits (1106), Expect = e-121, Method: Compositional matrix adjust. Identities = 209/209 (100%), Positives = 209/209 (100%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV 60 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV Sbjct: 3 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV 62 Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 120 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV Sbjct: 63 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 122 Query: 121 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR 180 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR Sbjct: 123 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR 182 Query: 181 VICNGKQPDMETDSSKSPDKAGLGKVKMK 209 VICNGKQPDMETDSSKSPDKAGLGKVKMK Sbjct: 183 VICNGKQPDMETDSSKSPDKAGLGKVKMK 211 >2R2I-A nrPDB Length = 198 Score = 200 bits (509), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 94/184 (51%), Positives = 139/184 (75%), Gaps = 5/184 (2%) Query: 10 DQKAV---PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDT 66 D KAV E H WY+ FM E PSG TL+EFK GL+ L+ ANK+++Q++ TFD Sbjct: 4 DSKAVEELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDF 63 Query: 67 NKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN-G 125 NKDG++DF+E++AA++L+++ K++QKL+WYFKLYD DGNG ID+ ELL++ A++A+N Sbjct: 64 NKDGYIDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRC 123 Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICN- 184 + ++ EEF N+VF KIDIN DGEL+LEEF+ G+ KD+ LL+I+ +S D ++++++I N Sbjct: 124 NEAMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILTRSLDLTHIVKLIQND 183 Query: 185 GKQP 188 GK P Sbjct: 184 GKNP 187 >2NA0-A nrPDB Length = 205 Score = 197 bits (500), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 93/201 (46%), Positives = 144/201 (71%), Gaps = 7/201 (3%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 +GKS+ + + + E H WY+ FM E PSG TL+EF+ GL+ L+ A+++++Q++ Sbjct: 6 DGKSV----EELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFE 61 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 TFD NKDG++DF+E+ AA++L+++ K+EQKL+WYFKLYD DGNG ID++ELL + A++A Sbjct: 62 TFDFNKDGYIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRA 121 Query: 123 LN--GQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR 180 +N T++ EEF + VF KID+N DGEL+LEEF+ G+ KDQ LL+ + +S D + ++R Sbjct: 122 INPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVR 181 Query: 181 VICNGKQPDMETDSSKSPDKA 201 + NG+Q D E S + + A Sbjct: 182 RLQNGEQ-DEEGASGRETEAA 201 >1JBA-A nrPDB Length = 204 Score = 130 bits (326), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 68/178 (38%), Positives = 109/178 (61%), Gaps = 17/178 (9%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 NG A D A QE WY+ F+ E PSG +HEFK + N++A ++++ ++ Sbjct: 13 NGAVGAAD--AAQLQE---WYKKFLEECPSGTLFMHEFKRFFKVPD-NEEATQYVEAMFR 66 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF----- 117 FDTN D +DFLE++AA+NL+++ +E KLKW FK+YD D NG ID+ ELLD+ Sbjct: 67 AFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYK 126 Query: 118 ------MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 + V+A + L+PEE ++ +F +D N DG+L+L EF+ G +D+ +++++ Sbjct: 127 LKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKML 184 >5T7C-A nrPDB Length = 193 Score = 122 bits (305), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 60/159 (37%), Positives = 96/159 (60%), Gaps = 6/159 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 E WY+ F+ + P+G T+ EFK + A+K + V+ TFDTN DG +DF E Sbjct: 25 HELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFRE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG------QQTLS 130 FI A+++ + K+EQKLKW F +YD DGNG I ++E+L++ A+ + + + Sbjct: 85 FIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDEST 144 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 PE+ + +F ++D NNDG+L+LEEFI G D ++ ++ Sbjct: 145 PEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183 >1BJF-A nrPDB Length = 193 Score = 120 bits (302), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 60/159 (37%), Positives = 93/159 (58%), Gaps = 6/159 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 E WY+ F+ + PSG ++ EFK + G A+K + V+ TFD N DG +DF E Sbjct: 25 HEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFRE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG------QQTLS 130 FI A+++ + K+EQKLKW F +YD DGNG I K E+L++ A+ + + + Sbjct: 85 FIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDEST 144 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 PE+ +F ++D N DG+L+LEEFI G D ++ ++ Sbjct: 145 PEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >5M6C-E nrPDB Length = 193 Score = 115 bits (288), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 56/158 (35%), Positives = 92/158 (58%), Gaps = 6/158 (3%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E WY+ F+ + P+G+ + EFK + A+K + V+ FDTN DG +DF EF Sbjct: 26 ELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSDGTIDFREF 85 Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG------QQTLSP 131 I A+++ + ++EQKL W F +YD DGNG I + E+L++ A+ + + +P Sbjct: 86 IIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTP 145 Query: 132 EEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 E+ +F ++D NNDG+L+LEEFI G D ++ ++ Sbjct: 146 EKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183 >2I94-A nrPDB Length = 202 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 58/186 (31%), Positives = 99/186 (53%), Gaps = 17/186 (9%) Query: 1 MGNGKSIAGDQKAV---------PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQ 51 MGN KS A ++ + +E WY++F+ E PSG T EF+T+ Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + V+ +FD N DG +DF E++ A+++ K QKL+W F LYD DGNG+I KN Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 112 ELLDMFMAV-QALNGQQTL-------SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 E+L++ A+ + ++ + T +PE+ ++ +D +LT +EFI G ++ Sbjct: 121 EVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANK 180 Query: 164 DLLEIV 169 ++L ++ Sbjct: 181 EILRLI 186 >2LCP-A nrPDB Length = 190 Score = 97.8 bits (242), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 53/159 (33%), Positives = 90/159 (56%), Gaps = 6/159 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E WY+ F+ + PSG F+ + K V+N FD NKDG ++F E Sbjct: 25 KEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG------QQTLS 130 FI A+++ + +++KL+W FKLYD D +G I +NE+LD+ A+ + G ++ + Sbjct: 85 FIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENT 144 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 PE+ ++ +F +D N DG+LTL+EF G D +++ + Sbjct: 145 PEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQAL 183 >2D8N-A nrPDB Length = 207 Score = 97.4 bits (241), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 49/161 (30%), Positives = 92/161 (57%), Gaps = 8/161 (4%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E WY++F+ + P+G T +F+++ + + V+ +FD+N DG +DF E Sbjct: 33 EELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKE 92 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------- 129 ++ A+++ K QKL+W F LYD DGNG+I KNE+L++ MA+ + + + Sbjct: 93 YVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDE 152 Query: 130 -SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 +PE+ ++ N+D +LT +EFI G ++++L ++ Sbjct: 153 NTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLI 193 >2L2E-A nrPDB Length = 190 Score = 97.1 bits (240), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 52/156 (33%), Positives = 86/156 (55%), Gaps = 6/156 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E WY+ F + PSG EF+ + + + V+N FD +K+G++DF E Sbjct: 25 KELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------S 130 FI A+++ + ++ KL W F+LYD D NG I +E+L + A+ + G + Sbjct: 85 FICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDT 144 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 PE+ +N +F+ +D N DG+LTLEEF G +D ++ Sbjct: 145 PEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIV 180 >1S1E-A nrPDB Length = 224 Score = 94.4 bits (233), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 48/157 (30%), Positives = 90/157 (57%), Gaps = 6/157 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E V YR F E PSG+ FK + + A+ + ++N FDT + G V F + Sbjct: 51 RELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFED 110 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------S 130 F+ A++++++ + +KL+W F LYD + +G I+K E++D+ A+ + G+ T + Sbjct: 111 FVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDT 170 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 167 P + +++ F K+D N DG +TL+EF+ +D +++ Sbjct: 171 PRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMR 207 >1S6C-A nrPDB Length = 183 Score = 94.0 bits (232), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 48/157 (30%), Positives = 90/157 (57%), Gaps = 6/157 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E V YR F E PSG+ FK + + A+ + ++N FDT + G V F + Sbjct: 18 RELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFED 77 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------S 130 F+ A++++++ + +KL+W F LYD + +G I+K E++D+ A+ + G+ T + Sbjct: 78 FVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDT 137 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 167 P + +++ F K+D N DG +TL+EF+ +D +++ Sbjct: 138 PRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMR 174 >6EPA-A nrPDB Length = 187 Score = 90.9 bits (224), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 48/158 (30%), Positives = 88/158 (55%), Gaps = 5/158 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E W++ F+ + P+GL T F + + +K V+ FD N DG ++F E Sbjct: 25 KEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL-----SP 131 FI A+++ + +++KL W F+LYD D +G I + E+ ++ A+ + GQQ +P Sbjct: 85 FIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTP 144 Query: 132 EEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 ++ ++ +F ++D N+D LTLEEF G D +++ + Sbjct: 145 QKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQAL 182 >3DD4-A nrPDB Length = 229 Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 6/162 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q +E + YR F E PSG+ FK + + + ++N FDT+ +G Sbjct: 58 QSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNG 117 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL- 129 V F +FI ++++++ +++KL W F LYD + +G I K E+LD+ A+ + G+ T Sbjct: 118 AVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYP 177 Query: 130 -----SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +P + + F K+D N DG +T++EFI KD++++ Sbjct: 178 VLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIM 219 >2JUL-A nrPDB Length = 256 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 46/162 (28%), Positives = 84/162 (51%), Gaps = 6/162 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q +E YR F E P+GL FK + A + ++N FD + +G Sbjct: 85 QTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL- 129 + F +F+ ++++++ + +KLKW F LYD + +G I K E+L + ++ + G+ T Sbjct: 145 AIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 Query: 130 -----SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +P E + F K+D N DG +T++EF+ KD++++ Sbjct: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 >2JU0-A nrPDB Length = 190 Score = 73.6 bits (179), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 77/156 (49%), Gaps = 6/156 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E W++ F+ + PSG +F + + ++ FD + +GF+ F E Sbjct: 25 REIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG------QQTLS 130 FI ++ + +E+KL W F+LYD + +G I +E+L + +V + G + + Sbjct: 85 FITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEAT 144 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 PE + +F +D N DG +TL+EF G D ++ Sbjct: 145 PEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 >2E6W-A nrPDB Length = 100 Score = 60.1 bits (144), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 49/84 (58%), Gaps = 6/84 (7%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------SPEEFINLVFHKI 142 + +KLKW F LYD + +G I K E+L + ++ + G+ T +P E + F K+ Sbjct: 7 VHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKM 66 Query: 143 DINNDGELTLEEFINGMAKDQDLL 166 D N DG +T+EEF+ KD++++ Sbjct: 67 DRNQDGVVTIEEFLEACQKDENIM 90 >4RGJ-A nrPDB Length = 520 Score = 57.8 bits (138), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 41/132 (31%), Positives = 69/132 (52%), Gaps = 22/132 (16%) Query: 40 FKTLLGLQGL------NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN----LIMQEKM 89 +K LL L+G N +DQ+ N+ D +++G++++ EF+ L+ E++ Sbjct: 397 YKELLKLKGEDTSDLDNAAIEYEVDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERL 456 Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E+ FKL+D DG+G I NEL +F G +S E + V ++D NNDGE Sbjct: 457 EKA----FKLFDKDGSGKISANELAQLF-------GLSDVSSECW-KTVLKEVDQNNDGE 504 Query: 150 LTLEEFINGMAK 161 + +EF + + K Sbjct: 505 IDFKEFRDMLVK 516 Score = 33.5 bits (75), Expect = 0.071, Method: Compositional matrix adjust. Identities = 26/95 (27%), Positives = 50/95 (52%), Gaps = 12/95 (12%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT-----LSPEEFINLVFHKIDIN 145 ++L FK D +G+G +D+NEL+ + + L G+ T + E ++ + + ID++ Sbjct: 371 KELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSIDLD 430 Query: 146 NDGELTLEEFINGMAKDQDL------LEIVYKSFD 174 +G + EF+ ++ D+ L LE +K FD Sbjct: 431 QNGYIEYSEFLT-VSIDRKLLLSTERLEKAFKLFD 464 >4IL1-A nrPDB Length = 823 Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 40/126 (31%), Positives = 66/126 (52%), Gaps = 7/126 (5%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN-LIMQEKME 90 SG ++ EF +L LQ N + +V + FDT+ +G VDF EFI V+ ++ E Sbjct: 192 SGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 246 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 QKL++ F++YD D +G I EL + + N + T ++ ++ D + DG + Sbjct: 247 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT-QLQQIVDKTIINADKDGDGRI 305 Query: 151 TLEEFI 156 + EEF Sbjct: 306 SFEEFC 311 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 27/135 (20%), Positives = 61/135 (45%), Gaps = 16/135 (11%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 68 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127 Query: 99 LYDADGNGSIDKNELLDMFMA-----VQALNGQQTLSPEEFINLV-----------FHKI 142 D DG+G ++ E + M A G + P E + F K+ Sbjct: 128 EADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKL 187 Query: 143 DINNDGELTLEEFIN 157 D++N G L++EEF++ Sbjct: 188 DLDNSGSLSVEEFMS 202 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 5/102 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E F+ Sbjct: 15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE----FL 70 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 + A + T S EE I F D + +G ++ E + M Sbjct: 71 TMMARKMKDTDSEEE-IREAFRVFDKDGNGYISAAELRHVMT 111 >4ORC-B nrPDB Length = 170 Score = 57.0 bits (136), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 40/125 (32%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN-LIMQEKME 90 SG ++ EF +L LQ N + +V + FDT+ +G VDF EFI V+ ++ E Sbjct: 35 SGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 QKL++ F++YD D +G I EL + + N + T ++ ++ D + DG + Sbjct: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT-QLQQIVDKTIINADKDGDGRI 148 Query: 151 TLEEF 155 + EEF Sbjct: 149 SFEEF 153 Score = 26.9 bits (58), Expect = 6.9, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 10/71 (14%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++L FK D D +GS+ E FM++ L QQ + I++ D + +GE+ Sbjct: 21 KRLGKRFKKLDLDNSGSLSVEE----FMSLPEL--QQNPLVQRVIDI----FDTDGNGEV 70 Query: 151 TLEEFINGMAK 161 +EFI G+++ Sbjct: 71 DFKEFIEGVSQ 81 >4YZB-A nrPDB Length = 491 Score = 56.6 bits (135), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 15/114 (13%) Query: 46 LQGLNQKANK-HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM---EQKLKWYFKLYD 101 + L+Q A + ++QV + D +K+GF+++ EF V + M K Q+L+ F ++D Sbjct: 376 VSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEF---VTVAMDRKTLLSRQRLERAFGMFD 432 Query: 102 ADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 ADG+G I +EL +F G + E + V ++D NNDGE+ EEF Sbjct: 433 ADGSGKISSSELATIF-------GVSEVDSETW-RRVLAEVDRNNDGEVDFEEF 478 Score = 30.4 bits (67), Expect = 0.54, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 6/75 (8%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTL----SPEEF-INLVFHKIDINNDGELT 151 F+ D +G+G +DK EL++ ++ + L G+ S EF + V +D + +G + Sbjct: 345 FQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIE 404 Query: 152 LEEFINGMAKDQDLL 166 EF+ +A D+ L Sbjct: 405 YSEFVT-VAMDRKTL 418 >5JN2-A nrPDB Length = 525 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 36/126 (28%), Positives = 69/126 (54%), Gaps = 22/126 (17%) Query: 40 FKTLLGLQG-----LNQKANKH-IDQVYNTFDTNKDGFVDFLEFIAAV----NLIMQEKM 89 +K L+ ++G L+ A +H +DQV + D +K+G++++ EF+ L+ +E++ Sbjct: 402 YKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERL 461 Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E+ F+++D+D +G I EL +F G + E + + V ++D NNDGE Sbjct: 462 ERA----FRMFDSDNSGKISSTELATIF-------GVSDVDSETWKS-VLSEVDKNNDGE 509 Query: 150 LTLEEF 155 + +EF Sbjct: 510 VDFDEF 515 Score = 31.6 bits (70), Expect = 0.22, Method: Compositional matrix adjust. Identities = 23/98 (23%), Positives = 47/98 (47%), Gaps = 12/98 (12%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ-----QTLSPEEFINLVFHKIDIN 145 ++L F D +G+G +D+ EL++ + + + GQ + E ++ V +D + Sbjct: 376 KELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFD 435 Query: 146 NDGELTLEEFINGMAKD------QDLLEIVYKSFDFSN 177 +G + EF+ +A D ++ LE ++ FD N Sbjct: 436 KNGYIEYSEFVT-VAMDRKTLLSRERLERAFRMFDSDN 472 >1JFJ-A nrPDB Length = 134 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 35/98 (35%), Positives = 55/98 (56%), Gaps = 5/98 (5%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + ++ D N DG V + E A V+ K EQ L+ FK DADGNG ID+NE + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 118 MAVQALNGQQTLSPEEF-INLVFHKIDINNDGELTLEE 154 ++Q Q LS ++ + +++ +D++ DG+LT EE Sbjct: 63 GSIQG----QDLSDDKIGLKVLYKLMDVDGDGKLTKEE 96 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 13/100 (13%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK---LKWYFKLYDADGNGSIDKNELLDM 116 ++ + D + +G +D EF I + + LK +KL D DG+G + K E+ Sbjct: 41 IFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSF 100 Query: 117 FMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F +G + ++ + K D N DG +TLEEF+ Sbjct: 101 FKK----HGIEKVAEQ------VMKADANGDGYITLEEFL 130 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 16/87 (18%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQA-LNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 FK D +G+G++ E V+A ++ ++ + E+ + L+F ID + +GE+ EF Sbjct: 6 FKEIDVNGDGAVSYEE-------VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEF 58 Query: 156 IN--GMAKDQDL------LEIVYKSFD 174 G + QDL L+++YK D Sbjct: 59 AKFYGSIQGQDLSDDKIGLKVLYKLMD 85 >1V1G-A nrPDB Length = 222 Score = 53.1 bits (126), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 37/139 (26%), Positives = 77/139 (55%), Gaps = 9/139 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM-QEKMEQ 91 GL EF+ L L + N D++++ FD ++G ++F EF+ ++ + + + Sbjct: 54 GLIHKEEFQ--LALFRNRNRRNLFADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHE 111 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV----FHKIDINND 147 K+K+ FKLYD G I++ EL +M +A+ L+ + + E+ I ++ F + D ND Sbjct: 112 KVKFAFKLYDLRQTGFIEREELKEMVVAL--LHESELVLSEDMIEVMVDKAFVQADRKND 169 Query: 148 GELTLEEFINGMAKDQDLL 166 G++ ++E+ + ++ + L+ Sbjct: 170 GKIDIDEWKDFVSLNPSLI 188 >2ZFD-A nrPDB Length = 226 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 40/138 (28%), Positives = 73/138 (52%), Gaps = 5/138 (3%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM-QEKMEQ 91 GL EF+ L L N+K + D+V++ FDT +G + F EF A+++ ++ Sbjct: 65 GLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDD 122 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEFINLVFHKIDINNDGE 149 K+ + F+LYD G I++ E+ M +A A +G + E+ I+ F + D +DG+ Sbjct: 123 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 182 Query: 150 LTLEEFINGMAKDQDLLE 167 + EE+ + + + LL+ Sbjct: 183 IDKEEWRSLVLRHPSLLK 200 >3U0K-A nrPDB Length = 442 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 16/133 (12%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM--- 89 G T E T++ G N + D + N D + DG +DF EF+ ++M KM Sbjct: 319 GTITTKELGTVMRSLGQNPTEAELQDMI-NEVDADGDGTIDFPEFL----IMMARKMKDT 373 Query: 90 --EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 E++++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ D Sbjct: 374 DSEEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGD 427 Query: 148 GELTLEEFINGMA 160 G++ EEF+ M Sbjct: 428 GQVNYEEFVQMMT 440 Score = 33.9 bits (76), Expect = 0.048, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADG+G+ID E L M Sbjct: 308 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLIMM- 366 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A + T S EE I F D + +G ++ E Sbjct: 367 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 399 Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 9/92 (9%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F L+D DG+G+I EL + ++ GQ E + + +++D Sbjct: 298 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMINEVDA 351 Query: 145 NNDGELTLEEFINGMA---KDQDLLEIVYKSF 173 + DG + EF+ MA KD D E + ++F Sbjct: 352 DGDGTIDFPEFLIMMARKMKDTDSEEEIREAF 383 Score = 29.6 bits (65), Expect = 0.99, Method: Compositional matrix adjust. Identities = 14/81 (17%), Positives = 39/81 (48%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF ++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 361 EFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 420 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 421 EADIDGDGQVNYEEFVQMMTA 441 >1UHN-A nrPDB Length = 189 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 40/138 (28%), Positives = 73/138 (52%), Gaps = 5/138 (3%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM-QEKMEQ 91 GL EF+ L L N+K + D+V++ FDT +G + F EF A+++ ++ Sbjct: 34 GLINKEEFQ--LALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDD 91 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEFINLVFHKIDINNDGE 149 K+ + F+LYD G I++ E+ M +A A +G + E+ I+ F + D +DG+ Sbjct: 92 KIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGK 151 Query: 150 LTLEEFINGMAKDQDLLE 167 + EE+ + + + LL+ Sbjct: 152 IDKEEWRSLVLRHPSLLK 169 >4OY4-A nrPDB Length = 415 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 66/129 (51%), Gaps = 8/129 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + D + N D + DG +DF EF+ + M++ E+ Sbjct: 33 GTITTKELGTVMRSLGQNPTEAELQDMI-NEVDADGDGTIDFPEFLTMMARKMKDTDSEE 91 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 92 EIREAFRVFDKDGNGYISAAELRHVMT-----NLGEKLTDEE-VDEMIREADIDGDGQVN 145 Query: 152 LEEFINGMA 160 EEF+ M Sbjct: 146 YEEFVQMMT 154 Score = 34.7 bits (78), Expect = 0.031, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADG+G+ID E L M Sbjct: 22 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLTMM- 80 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 A + T S EE I F D + +G ++ E + M Sbjct: 81 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAELRHVMT 118 Score = 34.7 bits (78), Expect = 0.032, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 9/92 (9%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F L+D DG+G+I EL + ++ GQ E + + +++D Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMINEVDA 65 Query: 145 NNDGELTLEEFINGMA---KDQDLLEIVYKSF 173 + DG + EF+ MA KD D E + ++F Sbjct: 66 DGDGTIDFPEFLTMMARKMKDTDSEEEIREAF 97 Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 40/81 (49%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 75 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 134 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 135 EADIDGDGQVNYEEFVQMMTA 155 >5YPX-A nrPDB Length = 223 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 29/126 (23%), Positives = 67/126 (53%), Gaps = 7/126 (5%) Query: 47 QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNG 106 Q N + +D+V+ FD + D ++ E++ +++ ++ +++K+++ F ++D +G+G Sbjct: 73 QKFNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDG 132 Query: 107 SIDKNELLDMFMAVQALNGQQTLS-PEE----FINLVFHKIDINNDGELTLEEFINGMAK 161 I + E+ M L Q T P+E + + K+D ++D L+ ++F + + Sbjct: 133 YISREEMFQMLKT--CLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLI 190 Query: 162 DQDLLE 167 + LLE Sbjct: 191 EPLLLE 196 >2JNF-A nrPDB Length = 158 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 12/146 (8%) Query: 20 HVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF-- 77 +R F SG + + +L + G+ Q+ I Q+ + FD +G +DF F Sbjct: 16 ETAFRDFETPEGSGRVSTDQIGIILEVLGI-QQTKSTIRQLIDEFDPFGNGDIDFDSFKI 74 Query: 78 IAAVNL---IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF 134 I A L + E+M+Q+L+ F+LYD +GNG I + + ++ + +TLS E+ Sbjct: 75 IGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAEL-----DETLSSED- 128 Query: 135 INLVFHKIDINNDGELTLEEFINGMA 160 ++ + +ID + G + EEF+ M Sbjct: 129 LDAMIDEIDADGSGTVDFEEFMGVMT 154 >3NCG-A nrPDB Length = 486 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 20/140 (14%) Query: 27 MMEYPSGLQTLHEFKTLLG------LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAA 80 M++ ++ HEF L G +Q ID + D + G +++ EFIA+ Sbjct: 347 MLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIAS 406 Query: 81 VN----LIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 L+ +E+ME+ FK++D DG+G I EL +F + ++ EE + Sbjct: 407 AIDRTILLSRERMERA----FKMFDKDGSGKISTKELFKLFSQADS-----SIQMEELES 457 Query: 137 LVFHKIDINNDGELTLEEFI 156 ++ ++D N DGE+ EF+ Sbjct: 458 II-EQVDNNKDGEVDFNEFV 476 Score = 26.9 bits (58), Expect = 5.5, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 128 TLSPEEFINLVFHKIDINNDGELTLEEFING 158 TL + + +F K+D NNDG L +E + G Sbjct: 326 TLDETKQLTEIFRKLDTNNDGMLDRDELVRG 356 >3HZT-A nrPDB Length = 467 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 14/112 (12%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM---EQKLKWYFKLYDADGNGSIDKNEL 113 +D + + D +++G++++ EF V + M +++ ++L F+ +D+DG+G I EL Sbjct: 363 VDHILQSVDFDRNGYIEYSEF---VTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEEL 419 Query: 114 LDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDL 165 +F + +E + V + D NNDGE+ EEF+ M K D+ Sbjct: 420 GRLFGVTEV--------DDETWHQVLQECDKNNDGEVDFEEFVEMMQKICDV 463 >2N6A-A nrPDB Length = 173 Score = 50.1 bits (118), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 27 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 85 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 86 EIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQVN 139 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 140 YEEFVQMM 147 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 16 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 74 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A + T S EE I F D + +G ++ E Sbjct: 75 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 107 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 9/85 (10%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F L+D DG+G+I EL + ++ GQ E + + +++D + +G + Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMINEVDADGNGTID 66 Query: 152 LEEFINGMA---KDQDLLEIVYKSF 173 EF+ MA KD D E + ++F Sbjct: 67 FPEFLTMMARKMKDTDSEEEIREAF 91 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 15/87 (17%), Positives = 40/87 (45%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 69 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 128 Query: 99 LYDADGNGSIDKNELLDMFMAVQALNG 125 D DG+G ++ E + M G Sbjct: 129 EADIDGDGQVNYEEFVQMMTGASTAAG 155 >3KHE-A nrPDB Length = 191 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 57/109 (52%), Gaps = 14/109 (12%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM---EQKLKWYFKLYDADGNGSIDKNE 112 +D + + D +++G++++ EF V + M +++ ++L F+ +D+DG+G I E Sbjct: 88 EVDHILQSVDFDRNGYIEYSEF---VTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEE 144 Query: 113 LLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 L +F + +E + V + D NNDGE+ EEF+ M K Sbjct: 145 LGRLFGVTEV--------DDETWHQVLQECDKNNDGEVDFEEFVEMMQK 185 >3EK4-A nrPDB Length = 451 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 66/129 (51%), Gaps = 8/129 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + D + N D + +G +DF EF+ + M++ E+ Sbjct: 328 GTITTKELGTVMRSLGQNPTEAELQDMI-NEVDADGNGTIDFPEFLTMMARKMKDTDSEE 386 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 387 EIREAFRVFDKDGNGYISAAELRHVMT-----NLGEKLTDEE-VDEMIREADIDGDGQVN 440 Query: 152 LEEFINGMA 160 EEF+ M Sbjct: 441 YEEFVQMMT 449 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 317 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 375 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 A + T S EE I F D + +G ++ E + M Sbjct: 376 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAELRHVMT 413 Score = 31.6 bits (70), Expect = 0.25, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 40/81 (49%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 370 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 429 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 430 EADIDGDGQVNYEEFVQMMTA 450 >2F2P-A nrPDB Length = 179 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 26 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 84 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 85 EIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQVN 138 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 139 YEEFVQMM 146 Score = 34.7 bits (78), Expect = 0.028, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 73 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A + T S EE I F D + +G ++ E Sbjct: 74 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 106 Score = 31.2 bits (69), Expect = 0.35, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 40/81 (49%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 68 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 128 EADIDGDGQVNYEEFVQMMTA 148 >6O20-F nrPDB Length = 169 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 8/129 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 46 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 104 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 105 EIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQVN 158 Query: 152 LEEFINGMA 160 EEF+ M Sbjct: 159 YEEFVQMMT 167 Score = 35.4 bits (80), Expect = 0.018, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 35 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 93 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A + T S EE I F D + +G ++ E Sbjct: 94 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 126 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 40/81 (49%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 88 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 147 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 148 EADIDGDGQVNYEEFVQMMTA 168 >3WFN-B nrPDB Length = 182 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 32 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 90 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 91 EIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQVN 144 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 145 YEEFVQMM 152 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 21 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 79 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A + T S EE I F D + +G ++ E Sbjct: 80 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 112 Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust. Identities = 16/89 (17%), Positives = 43/89 (48%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 74 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 133 Query: 99 LYDADGNGSIDKNELLDMFMAVQALNGQQ 127 D DG+G ++ E + M A G++ Sbjct: 134 EADIDGDGQVNYEEFVQMMTAKGGGGGEE 162 >4E53-A nrPDB Length = 185 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 33 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 91 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 92 EIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQVN 145 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 146 YEEFVQMM 153 Score = 35.0 bits (79), Expect = 0.020, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 22 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 80 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 A + T S EE I F D + +G ++ E + M Sbjct: 81 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAELRHVMT 118 >5I0I-E nrPDB Length = 145 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 8/129 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 24 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 82 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG++ Sbjct: 83 EIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQVN 136 Query: 152 LEEFINGMA 160 EEF+ M Sbjct: 137 YEEFVQMMT 145 Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ D + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 13 EAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM- 71 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A + T S EE I F D + +G ++ E Sbjct: 72 ---ARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 104 >6HCS-A nrPDB Length = 167 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 66/129 (51%), Gaps = 8/129 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 26 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEE 84 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL FM N + L+ EE ++ + + DI+ DG++ Sbjct: 85 EIREAFRVFDKDGNGYISAAELR-HFMT----NLGEKLTDEE-VDEMIREADIDGDGQVN 138 Query: 152 LEEFINGMA 160 EEF+ M Sbjct: 139 YEEFVQMMT 147 Score = 34.7 bits (78), Expect = 0.032, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L ++ + ++ FD + DG + E + + Q E +L+ DADGNG+I Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 D E F+ + A + T S EE I F D + +G ++ E Sbjct: 65 DFPE----FLTMMARKMKDTDSEEE-IREAFRVFDKDGNGYISAAEL 106 Score = 29.6 bits (65), Expect = 0.93, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 40/81 (49%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 68 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIR 127 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 128 EADIDGDGQVNYEEFVQMMTA 148 >2TN4-A nrPDB Length = 159 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 11/128 (8%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE----KMEQ 91 ++ E T++ + G + +D + D + G +DF EF+ + M+E K E+ Sbjct: 35 SVKELGTVMRMLG-QTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEE 93 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L F+++D + +G ID EL ++F A +G+ E I + D NNDG + Sbjct: 94 ELAELFRIFDRNADGYIDAEELAEIFRA----SGEHVTDEE--IESLMKDGDKNNDGRID 147 Query: 152 LEEFINGM 159 +EF+ M Sbjct: 148 FDEFLKMM 155 Score = 34.3 bits (77), Expect = 0.037, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 ++ FD + G + E + ++ Q +++L + D DG+G+ID E L M Sbjct: 22 AFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFL--VMM 79 Query: 120 VQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 V+ + EE + +F D N DG + EE Sbjct: 80 VRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEEL 115 Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust. Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 3/111 (2%) Query: 14 VPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQ---GLNQKANKHIDQVYNTFDTNKDG 70 PT+E + E SG EF ++ Q K+ + + +++ FD N DG Sbjct: 49 TPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADG 108 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 ++D E + +++++ K D + +G ID +E L M VQ Sbjct: 109 YIDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ 159 >1CLM-A nrPDB Length = 148 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 65/128 (50%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF++ + M+E+ E+ Sbjct: 25 GTITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLSLMARKMKEQDSEE 83 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L FK++D DGNG I EL + N + L+ +E ++ + + DI+ DG + Sbjct: 84 ELIEAFKVFDRDGNGLISAAELRHVMT-----NLGEKLTDDE-VDEMIREADIDGDGHIN 137 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 138 YEEFVRMM 145 Score = 34.3 bits (77), Expect = 0.040, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Query: 47 QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNG 106 Q L ++ + + FD + DG + E + + Q E +L+ DADGNG Sbjct: 2 QELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNG 61 Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 +ID E F+++ A ++ S EE I F D + +G ++ E + M Sbjct: 62 TIDFPE----FLSLMARKMKEQDSEEELIE-AFKVFDRDGNGLISAAELRHVM 109 Score = 28.1 bits (61), Expect = 3.1, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 39/81 (48%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF +L+ + Q + + + + + FD + +G + E + + ++ + ++ + Sbjct: 67 EFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIR 126 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G I+ E + M ++ Sbjct: 127 EADIDGDGHINYEEFVRMMVS 147 >3LIJ-A nrPDB Length = 494 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 16/109 (14%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAV----NLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 +D + D +++G++D+ EF+ +L+ ++K+E F+ +D DGNG I +E Sbjct: 392 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESA----FQKFDQDGNGKISVDE 447 Query: 113 LLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 L +F L+ ++ + +E I+ ID NNDG++ EEF + K Sbjct: 448 LASVF----GLDHLESKTWKEMIS----GIDSNNDGDVDFEEFCKMIQK 488 Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust. Identities = 36/174 (20%), Positives = 66/174 (37%), Gaps = 35/174 (20%) Query: 11 QKAVPTQET--HVWYRTFM------MEYPSGLQTLHEFKTLLGLQGLNQKA--------- 53 Q+ + Q+ H W + +E PS + + Q L Q A Sbjct: 281 QRRISAQQALEHPWIKEMCSKKESGIELPSLANAIENMRKFQNSQKLAQAALLYMASKLT 340 Query: 54 ----NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE--------KMEQKLKWYFKLYD 101 K + ++ D N DG +D E I + + E ++E ++ D Sbjct: 341 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 400 Query: 102 ADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 D NG ID +E + + M ++L + L F K D + +G+++++E Sbjct: 401 FDRNGYIDYSEFVTVAMDRKSLLSKDKLES------AFQKFDQDGNGKISVDEL 448 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 16/106 (15%) Query: 80 AVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL-----SPEEF 134 A L QE+ ++ L F+ D +G+G +D+ EL+D + L+G++ E Sbjct: 336 ASKLTSQEETKE-LTDIFRHIDKNGDGQLDRQELIDGY---SKLSGEEVAVFDLPQIESE 391 Query: 135 INLVFHKIDINNDGELTLEEFINGMAKDQ------DLLEIVYKSFD 174 ++ + D + +G + EF+ +A D+ D LE ++ FD Sbjct: 392 VDAILGAADFDRNGYIDYSEFVT-VAMDRKSLLSKDKLESAFQKFD 436 Score = 26.6 bits (57), Expect = 8.6, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 3/49 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 G ++ E ++ GL L K K ++ + D+N DG VDF EF + Sbjct: 441 GKISVDELASVFGLDHLESKTWK---EMISGIDSNNDGDVDFEEFCKMI 486 >5UKG-A nrPDB Length = 419 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 8/129 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM-EQ 91 G T E T++ G N + D + N D + DG DF EF+ + M ++ E+ Sbjct: 296 GTITTKELGTVMRSLGQNPTEAELQDMI-NEVDADGDGTFDFPEFLTMMARKMSYRVTEE 354 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + + + L+ EE ++ + DI+ DG++ Sbjct: 355 EIREAFRVFDKDGNGYIGAAELRHVMTDLG-----EKLTDEE-VDEMIRVADIDGDGQVN 408 Query: 152 LEEFINGMA 160 EEF+ M Sbjct: 409 YEEFVQMMT 417 Score = 33.1 bits (74), Expect = 0.080, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 6/82 (7%) Query: 80 AVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVF 139 A N + E+ + K F L+D DG+G+I EL + ++ GQ E + + Sbjct: 270 ASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMI 323 Query: 140 HKIDINNDGELTLEEFINGMAK 161 +++D + DG EF+ MA+ Sbjct: 324 NEVDADGDGTFDFPEFLTMMAR 345 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 40/81 (49%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 338 EFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIR 397 Query: 99 LYDADGNGSIDKNELLDMFMA 119 + D DG+G ++ E + M A Sbjct: 398 VADIDGDGQVNYEEFVQMMTA 418 Score = 30.8 bits (68), Expect = 0.39, Method: Compositional matrix adjust. Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 5/112 (4%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L ++ + ++ FD + DG + E + + Q E +L+ DADG+G+ Sbjct: 275 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTF 334 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 D E L M + ++ + T EE I F D + +G + E + M Sbjct: 335 DFPEFLTMM--ARKMSYRVT---EEEIREAFRVFDKDGNGYIGAAELRHVMT 381 >3Q5I-A nrPDB Length = 504 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 41/140 (29%), Positives = 73/140 (52%), Gaps = 19/140 (13%) Query: 29 EYPSGLQTLHEFKTLLG-LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 E G L FK LG L+ + ++ +D + D +K+G++++ EFI+ + M + Sbjct: 376 ELIEGYNVLRNFKNELGELKNVEEE----VDNILKEVDFDKNGYIEYSEFIS---VCMDK 428 Query: 88 KM---EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 ++ E++L+ F L+D D +G I K EL ++F G ++S E+ N V + D Sbjct: 429 QILFSEERLRRAFNLFDTDKSGKITKEELANLF-------GLTSIS-EKTWNDVLGEADQ 480 Query: 145 NNDGELTLEEFINGMAKDQD 164 N D + +EF++ M K D Sbjct: 481 NKDNMIDFDEFVSMMHKICD 500 Score = 31.6 bits (70), Expect = 0.24, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 45/83 (54%), Gaps = 4/83 (4%) Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEF 134 FI + ++E+ E L FK D +G+G +DK EL++ + ++ + + + EE Sbjct: 343 FIGSKLTTLEERKE--LTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEE 400 Query: 135 INLVFHKIDINNDGELTLEEFIN 157 ++ + ++D + +G + EFI+ Sbjct: 401 VDNILKEVDFDKNGYIEYSEFIS 423 Score = 30.4 bits (67), Expect = 0.63, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK 88 SG T E L GL +++K + V D NKD +DF EF++ ++ I K Sbjct: 449 SGKITKEELANLFGLTSISEKT---WNDVLGEADQNKDNMIDFDEFVSMMHKICDHK 502 >4I2Y-A nrPDB Length = 421 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + D + N D + DG DF EF+ + M + E+ Sbjct: 298 GTITTKELGTVMRSLGQNPTEAELQDMI-NEVDADGDGTFDFPEFLTMMARKMNDTDSEE 356 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG I EL + + + L+ EE ++ + DI+ DG++ Sbjct: 357 EIREAFRVFDKDGNGYIGAAELRHVMTDLG-----EKLTDEE-VDEMIRVADIDGDGQVN 410 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 411 YEEFVQMM 418 Score = 33.1 bits (74), Expect = 0.082, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 9/92 (9%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F L+D DG+G+I EL + ++ GQ E + + +++D Sbjct: 277 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMINEVDA 330 Query: 145 NNDGELTLEEFINGMAK---DQDLLEIVYKSF 173 + DG EF+ MA+ D D E + ++F Sbjct: 331 DGDGTFDFPEFLTMMARKMNDTDSEEEIREAF 362 Score = 32.3 bits (72), Expect = 0.14, Method: Compositional matrix adjust. Identities = 15/81 (18%), Positives = 41/81 (50%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF T++ + + + + I + + FD + +G++ E + + ++ ++++ + Sbjct: 340 EFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIR 399 Query: 99 LYDADGNGSIDKNELLDMFMA 119 + D DG+G ++ E + M A Sbjct: 400 VADIDGDGQVNYEEFVQMMTA 420 Score = 31.6 bits (70), Expect = 0.24, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 5/101 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADG+G+ D E L M Sbjct: 287 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMM- 345 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 + +N + EE I F D + +G + E + M Sbjct: 346 -ARKMNDTDS---EEEIREAFRVFDKDGNGYIGAAELRHVM 382 >3L19-A nrPDB Length = 214 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 32/110 (29%), Positives = 59/110 (53%), Gaps = 16/110 (14%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAV----NLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 +D + D +++G++D+ EF+ +L+ ++K+E F+ +D DGNG I + Sbjct: 108 EVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESA----FQKFDQDGNGKISVD 163 Query: 112 ELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 EL +F L+ ++ + +E I+ ID NNDG++ EEF + K Sbjct: 164 ELASVF----GLDHLESKTWKEMIS----GIDSNNDGDVDFEEFCKMIQK 205 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 51/114 (44%), Gaps = 14/114 (12%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE--------KMEQKLKWYFKLYD 101 +Q+ K + ++ D N DG +D E I + + E ++E ++ D Sbjct: 58 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 117 Query: 102 ADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 D NG ID +E + + M ++L + L F K D + +G+++++E Sbjct: 118 FDRNGYIDYSEFVTVAMDRKSLLSKDKLES------AFQKFDQDGNGKISVDEL 165 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 16/106 (15%) Query: 80 AVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL-----SPEEF 134 A L QE+ ++ L F+ D +G+G +D+ EL+D + L+G++ E Sbjct: 53 ASKLTSQEETKE-LTDIFRHIDKNGDGQLDRQELIDGY---SKLSGEEVAVFDLPQIESE 108 Query: 135 INLVFHKIDINNDGELTLEEFINGMAKDQ------DLLEIVYKSFD 174 ++ + D + +G + EF+ +A D+ D LE ++ FD Sbjct: 109 VDAILGAADFDRNGYIDYSEFVT-VAMDRKSLLSKDKLESAFQKFD 153 Score = 26.6 bits (57), Expect = 8.7, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 3/49 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 G ++ E ++ GL L K K ++ + D+N DG VDF EF + Sbjct: 158 GKISVDELASVFGLDHLESKTWK---EMISGIDSNNDGDVDFEEFCKMI 203 >2JNX-A nrPDB Length = 134 Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 5/98 (5%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + ++ D N DG V + E A V+ K EQ L+ FK D DGNG ID E Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFA 62 Query: 118 MAVQALNGQQTLSPEEF-INLVFHKIDINNDGELTLEE 154 AV+ +Q LS E+ + +++ +D + DG+LT EE Sbjct: 63 AAVK----EQDLSDEKVGLKILYKLMDADGDGKLTKEE 96 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 16/87 (18%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQA-LNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 FK DA+G+GS+ E V+A ++ ++ + E+ + L+F IDI+ +GE+ L EF Sbjct: 6 FKQLDANGDGSVSYEE-------VKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEF 58 Query: 156 INGMA--KDQDL------LEIVYKSFD 174 A K+QDL L+I+YK D Sbjct: 59 TKFAAAVKEQDLSDEKVGLKILYKLMD 85 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 13/100 (13%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK---LKWYFKLYDADGNGSIDKNELLDM 116 ++ D + +G +D EF + ++ + + LK +KL DADG+G + K E+ Sbjct: 41 IFKAIDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTF 100 Query: 117 FMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F + E+ ++ + K D N DG +TLEEF+ Sbjct: 101 F---------KKFGYEKVVDQIM-KADANGDGYITLEEFL 130 >5B8I-B nrPDB Length = 171 Score = 46.6 bits (109), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 12/140 (8%) Query: 20 HVWYRTFMMEY-PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFI 78 +W R ++ SG EF +L + +N ++ FD + G VDF EF+ Sbjct: 22 RLWKRFMKLDRDKSGTIERDEFLSLPQVS-----SNPLSTRMIAIFDEDGGGDVDFQEFV 76 Query: 79 AAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEFI 135 + ++ + E+KL++ FK+YD D +G I EL F+ ++ + G + + ++ + Sbjct: 77 SGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGEL---FIVLKMMVGSNLKDMQLQQIV 133 Query: 136 NLVFHKIDINNDGELTLEEF 155 + + D++ DG ++ EEF Sbjct: 134 DKTIMEADLDGDGRISFEEF 153 >4MVF-A nrPDB Length = 506 Score = 46.2 bits (108), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 7/128 (5%) Query: 36 TLHEFKTLLGLQGLN-QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLK 94 TL + L GL+ + QK I QV D+N G + + +F+AA + Q +++++ Sbjct: 376 TLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAAT-IDKQTYLKKEVC 434 Query: 95 WY-FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 FK +D DGNG I EL +F + + ++ I+ + ++D+N DGE+ Sbjct: 435 LIPFKFFDIDGNGKISVEELKRIF----GRDDIENPLIDKAIDSLLQEVDLNGDGEIDFH 490 Query: 154 EFINGMAK 161 EF+ M+K Sbjct: 491 EFMLMMSK 498 >3PM8-A nrPDB Length = 197 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 7/128 (5%) Query: 36 TLHEFKTLLGLQGLN-QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLK 94 TL + L GL+ + QK I QV D+N G + + +F+AA + Q +++++ Sbjct: 73 TLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAAT-IDKQTYLKKEVC 131 Query: 95 WY-FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 FK +D DGNG I EL +F + + ++ I+ + ++D+N DGE+ Sbjct: 132 LIPFKFFDIDGNGKISVEELKRIF----GRDDIENPLIDKAIDSLLQEVDLNGDGEIDFH 187 Query: 154 EFINGMAK 161 EF+ M+K Sbjct: 188 EFMLMMSK 195 >5A2H-A nrPDB Length = 149 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 64/128 (50%), Gaps = 8/128 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + N D + +G +DF EF+ + M++ E+ Sbjct: 26 GCITTKELGTVMRSLGQN-PTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEE 84 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +LK F+++D D NG I EL + N + L+ EE ++ + + D++ DG++ Sbjct: 85 ELKEAFRVFDKDQNGFISAAELRHVMT-----NLGEKLTDEE-VDEMIREADVDGDGQIN 138 Query: 152 LEEFINGM 159 EEF+ M Sbjct: 139 YEEFVKVM 146 Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust. Identities = 16/81 (19%), Positives = 41/81 (50%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 EF L+ + + + + + + + FD +++GF+ E + + ++ ++++ + Sbjct: 68 EFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIR 127 Query: 99 LYDADGNGSIDKNELLDMFMA 119 D DG+G I+ E + + MA Sbjct: 128 EADVDGDGQINYEEFVKVMMA 148 Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 9/85 (10%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F L+D DG+G I EL + ++ GQ E + + +++D + +G + Sbjct: 12 EFKEAFSLFDKDGDGCITTKELGTVMRSL----GQNPTEAE--LQDMINEVDADGNGTID 65 Query: 152 LEEFINGMA---KDQDLLEIVYKSF 173 EF+N MA KD D E + ++F Sbjct: 66 FPEFLNLMARKMKDTDSEEELKEAF 90 >1GGZ-A nrPDB Length = 148 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 8/126 (6%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQ 91 G T E T++ G N + + + D + +G VDF EF+ + M++ E+ Sbjct: 25 GCITTRELGTVMRSLGQN-PTEAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEE 83 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +++ F+++D DGNG + EL + + + LS EE ++ + D + DG++ Sbjct: 84 EIREAFRVFDKDGNGFVSAAELRHVMTRLG-----EKLSDEE-VDEMIRAADTDGDGQVN 137 Query: 152 LEEFIN 157 EEF+ Sbjct: 138 YEEFVR 143 Score = 33.1 bits (74), Expect = 0.096, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 5/103 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ D DGNG++D E L M M Sbjct: 14 EAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGM-M 72 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 A + + EE I F D + +G ++ E + M + Sbjct: 73 ARK----MKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTR 111 Score = 31.2 bits (69), Expect = 0.35, Method: Compositional matrix adjust. Identities = 20/104 (19%), Positives = 43/104 (41%), Gaps = 3/104 (2%) Query: 19 THVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKAN---KHIDQVYNTFDTNKDGFVDFL 75 T R M E +F LG+ K + I + + FD + +GFV Sbjct: 44 TEAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAA 103 Query: 76 EFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 E + + ++ ++++ + D DG+G ++ E + + ++ Sbjct: 104 ELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVS 147 >1TOP-A nrPDB Length = 162 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 11/128 (8%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE----KMEQ 91 + E T++ + G N + +D + D + G +DF EF+ + M+E K E+ Sbjct: 38 STKELGTVMRMLGQN-PTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEE 96 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L F+++D + +G ID EL ++ A G+ EE I + D NNDG + Sbjct: 97 ELANCFRIFDKNADGFIDIEELGEILRAT----GEHV--TEEDIEDLMKDSDKNNDGRID 150 Query: 152 LEEFINGM 159 +EF+ M Sbjct: 151 FDEFLKMM 158 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 3/110 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQ---GLNQKANKHIDQVYNTFDTNKDGF 71 PT+E + E SG EF ++ Q K+ + + + FD N DGF Sbjct: 53 PTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGF 112 Query: 72 VDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 +D E + + E+ ++ K D + +G ID +E L M VQ Sbjct: 113 IDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGVQ 162 Score = 35.0 bits (79), Expect = 0.023, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 ++ FD + G + E + ++ Q +++L + D DG+G+ID E L M M Sbjct: 25 AFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVM-MV 83 Query: 120 VQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 Q + S EE N F D N DG + +EE Sbjct: 84 RQMKEDAKGKSEEELAN-CFRIFDKNADGFIDIEEL 118 Score = 35.0 bits (79), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 6/83 (7%) Query: 79 AAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV 138 A + E+M + K F ++DADG G I EL V + GQ E ++ + Sbjct: 8 AEARAFLSEEMIAEFKAAFDMFDADGGGDISTKEL----GTVMRMLGQNPTKEE--LDAI 61 Query: 139 FHKIDINNDGELTLEEFINGMAK 161 ++D + G + EEF+ M + Sbjct: 62 IEEVDEDGSGTIDFEEFLVMMVR 84 >2AAO-A nrPDB Length = 166 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 13/132 (9%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG T E K L G N K ++ +D + D + G +D+ EFIAA + + + E Sbjct: 41 SGQITFEELKAGLKRVGANLKESEILD-LMQAADVDNSGTIDYKEFIAATLHLNKIERED 99 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALN--GQQTLSPEEFINLVFHKIDINNDGE 149 L F +D DG+G I +EL QA G + + EE + +D +NDG Sbjct: 100 HLFAAFTYFDKDGSGYITPDELQ------QACEEFGVEDVRIEELM----RDVDQDNDGR 149 Query: 150 LTLEEFINGMAK 161 + EF+ M K Sbjct: 150 IDYNEFVAMMQK 161 >3QRX-A nrPDB Length = 169 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADG 104 G GL ++ + I + ++ FDT+ G +D E A+ + E ++++K D DG Sbjct: 18 GRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDG 77 Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 +G+ID E L M A + S EE + F D +N G +T+++ Sbjct: 78 SGTIDFEEFLTMMTAKMG----ERDSREEILK-AFRLFDDDNSGTITIKDL 123 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 10/132 (7%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK--M 89 SG E K + G K + I ++ + D + G +DF EF+ + M E+ Sbjct: 42 SGTIDAKELKVAMRALGFEPK-KEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSR 100 Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E+ LK F+L+D D +G+I + D+ + L + L+ EE ++ + D N+D E Sbjct: 101 EEILKA-FRLFDDDNSGTI---TIKDLRRVAKELG--ENLTEEELQEMI-AEADRNDDNE 153 Query: 150 LTLEEFINGMAK 161 + +EFI M K Sbjct: 154 IDEDEFIRIMKK 165 >5E37-A nrPDB Length = 356 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 6/72 (8%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA----LNGQQTLSPEEFINLVFHKID 143 KME+ L+ FK+ D DGNG ID+ EL ++ ++++ + Q L PE+ + + D Sbjct: 27 KMEE-LERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWL-PEDELERCMEQYD 84 Query: 144 INNDGELTLEEF 155 +N DG ++ EEF Sbjct: 85 VNKDGVISFEEF 96 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 26/102 (25%), Positives = 51/102 (50%), Gaps = 7/102 (6%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAV-NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 +++ +D NKDG + F EF + + ++ E + + FK D GNG+I EL Sbjct: 75 ELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELS 134 Query: 115 DMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 +F ++ +S E+ ++L+ D ++ G++ EF+ Sbjct: 135 KLFASL-----GNPVSLEKLVDLM-QMYDKDDSGQIEFPEFL 170 >2LM5-A nrPDB Length = 214 Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/180 (23%), Positives = 82/180 (45%), Gaps = 28/180 (15%) Query: 17 QETHVWYRTFMMEYP-------SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN-- 67 QE + +R F P S L+ F+ +L L L KAN +++ F T+ Sbjct: 48 QEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL--KANPFKERICRVFSTSPA 105 Query: 68 KDG--FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 KD F DFL+ ++ + + K + F+++D D +G++++ +L + + Sbjct: 106 KDSLSFEDFLDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 163 Query: 126 QQTLSPEE---FINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVI 182 LS E I+ + + DI+ DG + L EF + ++ +S DF++ +++ Sbjct: 164 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH----------VISRSPDFASSFKIV 213 >2M7M-A nrPDB Length = 66 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 25/64 (39%), Positives = 35/64 (54%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + ++ D N DG V + E A V+ K EQ L+ FK DADGNG ID+NE + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 118 MAVQ 121 ++Q Sbjct: 63 GSIQ 66 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 28/42 (66%), Gaps = 5/42 (11%) Query: 138 VFHKIDINNDGELTLEE---FING--MAKDQDLLEIVYKSFD 174 +F +ID+N DG ++ EE F++ K++ LL++++KS D Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSID 46 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 FK D +G+G++ E+ ++ ++ + E+ + L+F ID + +GE+ EF Sbjct: 6 FKEIDVNGDGAVSYEEVKAF------VSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEF 58 >1DGU-A nrPDB Length = 183 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 75/162 (46%), Gaps = 18/162 (11%) Query: 17 QETHVWYRTFMMEYP-------SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN-- 67 QE + +R F P S L+ F+ +L L L KAN +++ F T+ Sbjct: 17 QEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL--KANPFKERICRVFSTSPA 74 Query: 68 KDG--FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 KD F DFL+ ++ + + K + F+++D D +G++++ +L + + Sbjct: 75 KDSLSFEDFLDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE 132 Query: 126 QQTLSPEE---FINLVFHKIDINNDGELTLEEFINGMAKDQD 164 LS E I+ + + DI+ DG + L EF + +++ D Sbjct: 133 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPD 174 >2L1W-A nrPDB Length = 149 Score = 43.1 bits (100), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 67/129 (51%), Gaps = 10/129 (7%) Query: 33 GLQTLHEFKTLLGLQGLNQK-ANKHIDQVYNTFDTNKDGFVDFLEFIA-AVNLIMQEKME 90 G T+ E T++ + L+Q + + + + D + +G ++F EF++ + E Sbjct: 25 GCITVEELATVI--RSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMAKKVKDTDAE 82 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++LK FK++D D NG I +EL + +N + L+ EE + + + D++ DG++ Sbjct: 83 EELKEAFKVFDKDQNGYISASELRHVM-----INLGEKLTDEE-VEQMIKEADLDGDGQV 136 Query: 151 TLEEFINGM 159 EEF+ M Sbjct: 137 NYEEFVKMM 145 Score = 34.7 bits (78), Expect = 0.028, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 5/101 (4%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + + FD + DG + E + + Q E++L+ DADGNG+I+ D F+ Sbjct: 14 EAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIE----FDEFL 69 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 ++ A + T + EE + F D + +G ++ E + M Sbjct: 70 SLMAKKVKDTDAEEE-LKEAFKVFDKDQNGYISASELRHVM 109 Score = 33.5 bits (75), Expect = 0.071, Method: Compositional matrix adjust. Identities = 21/91 (23%), Positives = 49/91 (53%), Gaps = 2/91 (2%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM-E 90 +G EF +L+ + + A + + + + FD +++G++ E + V + + EK+ + Sbjct: 60 NGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASE-LRHVMINLGEKLTD 118 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 ++++ K D DG+G ++ E + M M V+ Sbjct: 119 EEVEQMIKEADLDGDGQVNYEEFVKMMMTVR 149 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 6/78 (7%) Query: 84 IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKID 143 I+ E+ K F L+D DG+G I EL +++L+ Q + EE +++ ++D Sbjct: 3 ILSEEQIVDFKEAFGLFDKDGDGCITVEELA---TVIRSLD--QNPTEEELQDMI-SEVD 56 Query: 144 INNDGELTLEEFINGMAK 161 + +G + +EF++ MAK Sbjct: 57 ADGNGTIEFDEFLSLMAK 74 >2AMI-A nrPDB Length = 96 Score = 43.1 bits (100), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 39/75 (52%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADG 104 G GL ++ + I + ++ FDT+ G +D E A+ + E ++++K D DG Sbjct: 20 GRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDG 79 Query: 105 NGSIDKNELLDMFMA 119 +G+ID E L M A Sbjct: 80 SGTIDFEEFLTMMTA 94 >3AAJ-A nrPDB Length = 167 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 15/118 (12%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + + + FD V+F EF I + F+ YD D +G IDKNEL Sbjct: 43 VRSIISMFDRENKAGVNFSEFTGVWKYITDWQN------VFRTYDRDNSGMIDKNELK-- 94 Query: 117 FMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 QAL+G + ++F +++ K D G++ ++FI G Q L +I ++ +D Sbjct: 95 ----QALSGYRL--SDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDI-FRRYD 145 >5E1J-A nrPDB Length = 741 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M + + L+ F L D+D NG IDKN+ + +F + +S EEF L+F ++D Sbjct: 319 MDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEF-GLIFDELDD 377 Query: 145 NNDGELTLEEF 155 D ++ +EF Sbjct: 378 TRDFKINKDEF 388 >5MWC-D nrPDB Length = 311 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 35/69 (50%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 + + + + + TFD + DGF+D EF + L ++ ++ F D D NG ID +E Sbjct: 149 SEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDE 208 Query: 113 LLDMFMAVQ 121 L M VQ Sbjct: 209 FLKMVENVQ 217 Score = 34.3 bits (77), Expect = 0.040, Method: Compositional matrix adjust. Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 + A +L E++L F+ +D DG+G ID+ E F + L G+Q +E + Sbjct: 138 VMANSLTAMVPSEEELSECFRTFDKDGDGFIDREE----FGGIIRLTGEQLT--DEDPDE 191 Query: 138 VFHKIDINNDGELTLEEFI 156 +F D + +G + +EF+ Sbjct: 192 IFGDSDTDKNGRIDFDEFL 210 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 14 VPTQET-HVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV 72 VP++E +RTF + G EF ++ L G Q ++ D+++ DT+K+G + Sbjct: 147 VPSEEELSECFRTFDKD-GDGFIDREEFGGIIRLTG-EQLTDEDPDEIFGDSDTDKNGRI 204 Query: 73 DFLEFIAAV 81 DF EF+ V Sbjct: 205 DFDEFLKMV 213 >2M29-A nrPDB Length = 171 Score = 40.4 bits (93), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 10/92 (10%) Query: 70 GFVDFLEFIAAVNLIMQEKME-----QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 GFVDF EF+ ++ ++E+ ++L+ F+ +D D +G I EL A AL Sbjct: 79 GFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQ---AAPALL 135 Query: 125 GQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 G+ E ++ + ++D+N DG + +EF+ Sbjct: 136 GEPLEGTE--LDEMLREMDLNGDGTIDFDEFV 165 >3KF9-A nrPDB Length = 149 Score = 40.0 bits (92), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 38/72 (52%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 GL ++ + I + ++ FDT+ G +D E A+ + E ++++K D DG+G+ Sbjct: 1 GLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGT 60 Query: 108 IDKNELLDMFMA 119 ID E L M A Sbjct: 61 IDFEEFLQMMTA 72 >1DTL-A nrPDB Length = 161 Score = 40.0 bits (92), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 11/146 (7%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F++ G + E ++ + G N + + ++ + D + G VDF EF Sbjct: 19 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTP-EELQEMIDEVDEDGSGTVDFDEF 77 Query: 78 IAAVNLIMQE----KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + + M++ K E++L F+++D + +G ID EL M A +T++ E+ Sbjct: 78 LVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG-----ETIT-ED 131 Query: 134 FINLVFHKIDINNDGELTLEEFINGM 159 I + D NNDG + +EF+ M Sbjct: 132 DIEELMKDGDKNNDGRIDYDEFLEFM 157 Score = 31.6 bits (70), Expect = 0.22, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 33/70 (47%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 K+ + + ++ FD N DG++D E + + E ++ K D + +G ID + Sbjct: 92 KSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYD 151 Query: 112 ELLDMFMAVQ 121 E L+ V+ Sbjct: 152 EFLEFMKGVE 161 >4ZCV-A nrPDB Length = 165 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 13/96 (13%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 ++++ T D NKDG +DF EF+ + + E+K+K FK D + +G I+ +E+ Sbjct: 52 EKIFTTGDVNKDGKLDFEEFMKYL-----KDHEKKMKLAFKSLDKNNDGKIEASEI---- 102 Query: 118 MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 VQ+L E+ L+ ID+ DG +T++ Sbjct: 103 --VQSLQTLGLTISEQQAELILQSIDV--DGTMTVD 134 Score = 33.1 bits (74), Expect = 0.085, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 6/81 (7%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F+ D +G+G +D EL + + GQ EE I F D+N DG+L EEF+ Sbjct: 19 FQALDRNGDGVVDIGELQEGLRNLGIPLGQ---DAEEKI---FTTGDVNKDGKLDFEEFM 72 Query: 157 NGMAKDQDLLEIVYKSFDFSN 177 + + +++ +KS D +N Sbjct: 73 KYLKDHEKKMKLAFKSLDKNN 93 Score = 30.4 bits (67), Expect = 0.57, Method: Compositional matrix adjust. Identities = 16/64 (25%), Positives = 31/64 (48%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 K + + + D N DG ++ E + ++ + EQ+ + + D DG ++D NE Sbjct: 80 KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWR 139 Query: 115 DMFM 118 D F+ Sbjct: 140 DYFL 143 >4N5X-A nrPDB Length = 199 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 13/96 (13%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 ++++ T D NKDG +DF EF+ + + E+K+K FK D + +G I+ +E+ Sbjct: 61 EKIFTTGDVNKDGKLDFEEFMKYL-----KDHEKKMKLAFKSLDKNNDGKIEASEI---- 111 Query: 118 MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 VQ+L E+ L+ ID+ DG +T++ Sbjct: 112 --VQSLQTLGLTISEQQAELILQSIDV--DGTMTVD 143 Score = 33.1 bits (74), Expect = 0.080, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 6/81 (7%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F+ D +G+G +D EL + + GQ EE I F D+N DG+L EEF+ Sbjct: 28 FQALDRNGDGVVDIGELQEGLRNLGIPLGQ---DAEEKI---FTTGDVNKDGKLDFEEFM 81 Query: 157 NGMAKDQDLLEIVYKSFDFSN 177 + + +++ +KS D +N Sbjct: 82 KYLKDHEKKMKLAFKSLDKNN 102 Score = 30.4 bits (67), Expect = 0.55, Method: Compositional matrix adjust. Identities = 16/64 (25%), Positives = 31/64 (48%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 K + + + D N DG ++ E + ++ + EQ+ + + D DG ++D NE Sbjct: 89 KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWR 148 Query: 115 DMFM 118 D F+ Sbjct: 149 DYFL 152 >2LAP-A nrPDB Length = 167 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 56/108 (51%), Gaps = 10/108 (9%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNL-IMQEKME----QKLKWYFKLYDADGNGSIDKNEL 113 ++ + N G VDF +F+ + ++ E + ++L+ F+ +D +G+G I +EL Sbjct: 65 ELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSEL 124 Query: 114 LDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + A++ L G Q + I + +D+N DG + EEF+ M++ Sbjct: 125 RE---AMRKLLGHQVGHRD--IEEIIRDVDLNGDGRVDFEEFVRMMSR 167 Score = 28.1 bits (61), Expect = 2.9, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 4/43 (9%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 + LLG +Q ++ I+++ D N DG VDF EF+ ++ Sbjct: 128 MRKLLG----HQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMS 166 >2LHI-A nrPDB Length = 176 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 16/98 (16%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF-INLVFHKID 143 + E+ + K F L+D D NGSI +EL + ++ LSP E +N + ++ID Sbjct: 5 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSL-------GLSPSEAEVNDLMNEID 57 Query: 144 INNDGELTLEEFINGMAK-------DQDLLEIVYKSFD 174 ++ + ++ EF+ M++ +Q+LLE +K FD Sbjct: 58 VDGNHQIEFSEFLALMSRQLKSNDSEQELLE-AFKVFD 94 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYF 97 E T++ GL+ + ++ + N D + + ++F EF+A ++ ++ EQ+L F Sbjct: 32 ELATVMRSLGLS-PSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAF 90 Query: 98 KLYDADGNGSIDKNELLDMFMAV 120 K++D +G+G I EL + ++ Sbjct: 91 KVFDKNGDGLISAAELKHVLTSI 113 >4JWQ-A nrPDB Length = 199 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 4/116 (3%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWY-FKLYDAD 103 GL+ K ++ D + + D++ G +D+ EF+AA + ++ + +KL + F+++D D Sbjct: 83 GLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFLAAA--LDRKHLSKKLIYCAFRVFDVD 140 Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 +G I EL + G T + + ++D NNDG++ EF M Sbjct: 141 NDGEITTAELAHILYNGNK-KGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMM 195 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 13/92 (14%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q+LK F D DG G+I KN+L + L P+ F +++ +ID + G + Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQL------KKGLENSGLKLPQNF-DVLLDQIDSDGSGRI 110 Query: 151 TLEEFINGMAKDQ-----DLLEIVYKSFDFSN 177 EF+ A D+ L+ ++ FD N Sbjct: 111 DYTEFL-AAALDRKHLSKKLIYCAFRVFDVDN 141 >3K21-A nrPDB Length = 191 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 8/134 (5%) Query: 25 TFMM--EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 TF++ E G T + K L GL N D + + D++ G +D+ EFIAA Sbjct: 57 TFLVLDEDGKGYITKEQLKKGLEKDGLKLPYN--FDLLLDQIDSDGSGKIDYTEFIAAA- 113 Query: 83 LIMQEKMEQKLKWY-FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + ++++ +KL + F+++D D +G I EL + G T + + Sbjct: 114 -LDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNK-KGNITQRDVNRVKRMIRD 171 Query: 142 IDINNDGELTLEEF 155 +D NNDG++ EF Sbjct: 172 VDKNNDGKIDFHEF 185 Score = 26.6 bits (57), Expect = 9.0, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 14/105 (13%) Query: 80 AVNLIMQEKME---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 A+ +I Q+ + +KLK F + D DG G I K +L + L P F + Sbjct: 38 AMTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQL------KKGLEKDGLKLPYNF-D 90 Query: 137 LVFHKIDINNDGELTLEEFINGMAK----DQDLLEIVYKSFDFSN 177 L+ +ID + G++ EFI + L+ ++ FD N Sbjct: 91 LLLDQIDSDGSGKIDYTEFIAAALDRKQLSKKLIYCAFRVFDVDN 135 >2LMV-A nrPDB Length = 148 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 8/126 (6%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-ME 90 +G E TL+ G N + D + + N +G ++F EF + M+E E Sbjct: 24 TGKIATRELGTLMRTLGQNPTEAELQDLIAEA-ENNNNGQLNFTEFCGIMAKQMRETDTE 82 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++++ FK++D DG+G I EL F+ + N + ++ EE I+ + + D + DG + Sbjct: 83 EEMREAFKIFDRDGDGFISPAEL--RFVMI---NLGEKVTDEE-IDEMIREADFDGDGMI 136 Query: 151 TLEEFI 156 EEF+ Sbjct: 137 NYEEFV 142 >1S6I-A nrPDB Length = 188 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 17/134 (12%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG T E K L G ++ I + + D +K G +D+ EFIAA + + + E+ Sbjct: 24 SGTITFDELKDGLKRVG-SELMESEIKDLMDAADIDKSGTIDYGEFIAATVHLNKLEREE 82 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS----PEEFINLVFHKIDINND 147 L F +D DG+G I +E+ QQ + I+ + +ID +ND Sbjct: 83 NLVSAFSYFDKDGSGYITLDEI------------QQACKDFGLDDIHIDDMIKEIDQDND 130 Query: 148 GELTLEEFINGMAK 161 G++ EF M K Sbjct: 131 GQIDYGEFAAMMRK 144 Score = 33.1 bits (74), Expect = 0.087, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 +++ DT+ G + F E + + E ME ++K D D +G+ID E + Sbjct: 14 ELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFI---A 70 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 A LN L EE + F D + G +TL+E Sbjct: 71 ATVHLN---KLEREENLVSAFSYFDKDGSGYITLDEI 104 >2K7C-A nrPDB Length = 72 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 5/71 (7%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++L+ F+ +D +G+G I +EL + A++ L G Q + I + +D+N DG + Sbjct: 7 KELRDAFREFDTNGDGEISTSELRE---AMRKLLGHQVGHRD--IEEIIRDVDLNGDGRV 61 Query: 151 TLEEFINGMAK 161 EEF+ M++ Sbjct: 62 DFEEFVRMMSR 72 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFI 78 + LLG +Q ++ I+++ D N DG VDF EF+ Sbjct: 34 RKLLG----HQVGHRDIEEIIRDVDLNGDGRVDFEEFV 67 >1LKJ-A nrPDB Length = 146 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 16/98 (16%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF-INLVFHKID 143 + E+ + K F L+D D NGSI +EL + ++ LSP E +N + ++ID Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSL-------GLSPSEAEVNDLMNEID 56 Query: 144 INNDGELTLEEFINGMAK-------DQDLLEIVYKSFD 174 ++ + ++ EF+ M++ +Q+LLE +K FD Sbjct: 57 VDGNHQIEFSEFLALMSRQLKSNDSEQELLE-AFKVFD 93 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYF 97 E T++ GL+ + ++ + N D + + ++F EF+A ++ ++ EQ+L F Sbjct: 31 ELATVMRSLGLS-PSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAF 89 Query: 98 KLYDADGNGSIDKNELLDMFMAV 120 K++D +G+G I EL + ++ Sbjct: 90 KVFDKNGDGLISAAELKHVLTSI 112 >2LHH-A nrPDB Length = 128 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 16/98 (16%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF-INLVFHKID 143 + E+ + K F L+D D NGSI +EL + ++ LSP E +N + ++ID Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSL-------GLSPSEAEVNDLMNEID 56 Query: 144 INNDGELTLEEFINGMAK-------DQDLLEIVYKSFD 174 ++ + ++ EF+ M++ +Q+LLE +K FD Sbjct: 57 VDGNHQIEFSEFLALMSRQLKSNDSEQELLE-AFKVFD 93 Score = 31.6 bits (70), Expect = 0.24, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYF 97 E T++ GL+ + ++ + N D + + ++F EF+A ++ ++ EQ+L F Sbjct: 31 ELATVMRSLGLS-PSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAF 89 Query: 98 KLYDADGNGSIDKNELLDMFMAV 120 K++D +G+G I EL + ++ Sbjct: 90 KVFDKNGDGLISAAELKHVLTSI 112 >2NCO-A nrPDB Length = 102 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP-EEFINLVFHKIDINNDGELTLEEF 155 FK YD DG+G + +E+ + A G +P +E + + D N+DG ++LEE+ Sbjct: 21 FKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSLEEY 80 >2K2A-A nrPDB Length = 70 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 41/72 (56%), Gaps = 6/72 (8%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 M+Q+L+ F+LYD +GNG I + + ++ + +TLS E+ ++ + +ID + G Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAEL-----DETLSSED-LDAMIDEIDADGSG 54 Query: 149 ELTLEEFINGMA 160 + EEF+ M Sbjct: 55 TVDFEEFMGVMT 66 >1FW4-A nrPDB Length = 71 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 6/71 (8%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E++++ F+++D DGNG I EL + N + L+ EE ++ + + DI+ DG+ Sbjct: 5 EEEIREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQ 58 Query: 150 LTLEEFINGMA 160 + EEF+ M Sbjct: 59 VNYEEFVQMMT 69 Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust. Identities = 12/67 (17%), Positives = 33/67 (49%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 + + I + + FD + +G++ E + + ++ ++++ + D DG+G ++ E Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 63 Query: 113 LLDMFMA 119 + M A Sbjct: 64 FVQMMTA 70 >1C7W-A nrPDB Length = 81 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 9/73 (12%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKL-----KWYFKLYDAD 103 + Q + I + + FD N DG +DF EF IMQ+ E+ L + K D D Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEF----KFIMQKVGEEPLTDAEVEEAMKEADED 57 Query: 104 GNGSIDKNELLDM 116 GNG ID E +D+ Sbjct: 58 GNGVIDIPEFMDL 70 >2LV7-A nrPDB Length = 100 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 6/67 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++++ FK++D DGNG I K EL A+ + E + ++ ++D++ DG++ Sbjct: 36 EEIREAFKVFDRDGNGFISKQEL------GTAMRSLGYMPNEVELEVIIQRLDMDGDGQV 89 Query: 151 TLEEFIN 157 EEF+ Sbjct: 90 DFEEFVT 96 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/63 (23%), Positives = 30/63 (47%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 + I + + FD + +GF+ E A+ + E +L+ + D DG+G +D E + Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFV 95 Query: 115 DMF 117 + Sbjct: 96 TLL 98 >2B1U-A nrPDB Length = 71 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 6/72 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 + L+ F+ +D DG+G I +EL +A+ G P+E ++ + + D++ DG + Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELR------RAMAGLGQPLPQEELDAMIREADVDQDGRV 59 Query: 151 TLEEFINGMAKD 162 EEF +A++ Sbjct: 60 NYEEFARMLAQE 71 >5Z1Q-A nrPDB Length = 95 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 39/70 (55%) Query: 47 QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNG 106 Q L+++ + I + ++ FDTNK G +D+ E A+ + + + ++ YD +GNG Sbjct: 19 QELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNG 78 Query: 107 SIDKNELLDM 116 I ++ LD+ Sbjct: 79 YIGFDDFLDI 88 >2M97-A nrPDB Length = 69 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 35/69 (50%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 + + + + + FD + +GF+D EF + L ++ ++ + F D D NG ID +E Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 113 LLDMFMAVQ 121 L M VQ Sbjct: 61 FLKMMENVQ 69 Score = 31.2 bits (69), Expect = 0.37, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E +R F + +G EF ++ L G Q ++ +D+++ DT+K+G +DF E Sbjct: 3 EELSECFRIFDKD-GNGFIDREEFGDIIRLTG-EQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 77 FI 78 F+ Sbjct: 61 FL 62 >1H4B-A nrPDB Length = 84 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 9/88 (10%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 Q+K E++ FK +DA+G+G I EL +AL +++P+E + + +ID + Sbjct: 6 QDKAERE--RIFKRFDANGDGKISAAEL------GEALKTLGSITPDE-VKHMMAEIDTD 56 Query: 146 NDGELTLEEFINGMAKDQDLLEIVYKSF 173 DG ++ +EF + ++ LL+ V K F Sbjct: 57 GDGFISFQEFTDFGRANRGLLKDVAKIF 84 >2ROB-A nrPDB Length = 70 Score = 37.0 bits (84), Expect = 0.007, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 6/70 (8%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E++LK FK++D D NG I +EL + +N + L+ EE + + + D++ DG+ Sbjct: 3 EEELKEAFKVFDKDQNGYISASELRHVM-----INLGEKLTDEE-VEQMIKEADLDGDGQ 56 Query: 150 LTLEEFINGM 159 + EEF+ M Sbjct: 57 VNYEEFVKMM 66 Score = 30.0 bits (66), Expect = 0.72, Method: Compositional matrix adjust. Identities = 14/69 (20%), Positives = 37/69 (53%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 A + + + + FD +++G++ E + + ++ +++++ K D DG+G ++ E Sbjct: 2 AEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEE 61 Query: 113 LLDMFMAVQ 121 + M M V+ Sbjct: 62 FVKMMMTVR 70 >5COC-A nrPDB Length = 130 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 36/80 (45%) Query: 37 LHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWY 96 L E K L Q ++ + ++ FD + DG + E + + Q E +L+ Sbjct: 45 LAEAKCLNDAQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM 104 Query: 97 FKLYDADGNGSIDKNELLDM 116 DADGNG+ID E L M Sbjct: 105 INEVDADGNGTIDFPEFLTM 124 >2KN2-A nrPDB Length = 92 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 6/70 (8%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E++LK FK++D D NG I +EL + +N + L+ EE + + + D++ DG+ Sbjct: 8 EEELKEAFKVFDKDQNGYISASELRHVM-----INLGEKLTDEE-VEQMIKEADLDGDGQ 61 Query: 150 LTLEEFINGM 159 + EEF+ M Sbjct: 62 VNYEEFVKMM 71 Score = 30.4 bits (67), Expect = 0.58, Method: Compositional matrix adjust. Identities = 14/73 (19%), Positives = 39/73 (53%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 ++ A + + + + FD +++G++ E + + ++ +++++ K D DG+G + Sbjct: 3 MDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQV 62 Query: 109 DKNELLDMFMAVQ 121 + E + M M V+ Sbjct: 63 NYEEFVKMMMTVR 75 >2GGM-A nrPDB Length = 172 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 9/92 (9%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ +Q+++ F L+DADG G+ID EL +A++AL + +E I + +ID Sbjct: 25 LTEEQKQEIREAFDLFDADGTGTIDVKELK---VAMRALGFE---PKKEEIKKMISEIDK 78 Query: 145 NNDGELTLEEFINGMAK---DQDLLEIVYKSF 173 G++ +F+ M + ++D E + K+F Sbjct: 79 EGTGKMNFGDFLTVMTQKMSEKDTKEEILKAF 110 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 8/131 (6%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-ME 90 +G + E K + G K + I ++ + D G ++F +F+ + M EK + Sbjct: 45 TGTIDVKELKVAMRALGFEPK-KEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTK 103 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 +++ FKL+D D G I ++ + L + L+ EE ++ + D + DGE+ Sbjct: 104 EEILKAFKLFDDDETGKIS---FKNLKRVAKELG--ENLTDEELQEMI-DEADRDGDGEV 157 Query: 151 TLEEFINGMAK 161 + +EF+ M K Sbjct: 158 SEQEFLRIMKK 168 >2HF5-A nrPDB Length = 68 Score = 36.6 bits (83), Expect = 0.009, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 32/53 (60%), Gaps = 1/53 (1%) Query: 62 NTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNEL 113 N D + +G +DF EF+ + M++ E++++ F+++D DGNG I EL Sbjct: 8 NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 >1JC2-A nrPDB Length = 76 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 34/70 (48%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 K+ + + + FD N DGF+D E + + +E+ ++ K D + +G ID + Sbjct: 7 KSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFD 66 Query: 112 ELLDMFMAVQ 121 E L M VQ Sbjct: 67 EFLKMMEGVQ 76 Score = 33.1 bits (74), Expect = 0.081, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 6/72 (8%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 K E++L F+++D + +G ID EL ++ A G+ + EE I + D NND Sbjct: 7 KSEEELANCFRIFDKNADGFIDIEELGEILRAT----GEHVI--EEDIEDLMKDSDKNND 60 Query: 148 GELTLEEFINGM 159 G + +EF+ M Sbjct: 61 GRIDFDEFLKMM 72 >2OPO-A nrPDB Length = 86 Score = 36.2 bits (82), Expect = 0.011, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 43/77 (55%), Gaps = 7/77 (9%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 FK +D +G+G I +EL D AL +++P+E + + +ID + DG ++ +EF Sbjct: 17 FKRFDTNGDGKISSSELGD------ALKTLGSVTPDE-VRRMMAEIDTDGDGFISFDEFT 69 Query: 157 NGMAKDQDLLEIVYKSF 173 + ++ L++ V K F Sbjct: 70 DFARANRGLVKDVSKIF 86 >2OBH-A nrPDB Length = 143 Score = 35.8 bits (81), Expect = 0.012, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 50/90 (55%), Gaps = 9/90 (10%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 146 E+ +Q+++ F L+DADG G+ID EL +A++AL + +E I + +ID Sbjct: 2 EEQKQEIREAFDLFDADGTGTIDVKELK---VAMRALGFE---PKKEEIKKMISEIDKEG 55 Query: 147 DGELTLEEFINGMAK---DQDLLEIVYKSF 173 G++ +F+ M + ++D E + K+F Sbjct: 56 TGKMNFGDFLTVMTQKMSEKDTKEEILKAF 85 Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 10/132 (7%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-ME 90 +G + E K + G K + I ++ + D G ++F +F+ + M EK + Sbjct: 20 TGTIDVKELKVAMRALGFEPK-KEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTK 78 Query: 91 QKLKWYFKLYDADGNGSID-KNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 +++ FKL+D D G I KN + A + L+ EE ++ + D + DGE Sbjct: 79 EEILKAFKLFDDDETGKISFKN------LKRVAKELGENLTDEELQEMI-DEADRDGDGE 131 Query: 150 LTLEEFINGMAK 161 ++ +EF+ M K Sbjct: 132 VSEQEFLRIMKK 143 >2G9B-A nrPDB Length = 263 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 23/101 (22%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQ---------VYNTFDTNKDGFVDFLEFIAAVN 82 SG E K L + L +KANK +D + FD+N DG ++ E A Sbjct: 117 SGFIETEELKNFL--KDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM--ARL 172 Query: 83 LIMQEKMEQKLKWY----------FKLYDADGNGSIDKNEL 113 L +QE K + F+LYD DGNG ID+NEL Sbjct: 173 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 213 >2KZ2-A nrPDB Length = 94 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 6/71 (8%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E++++ F++ D DGNG I EL + N + L+ EE ++ + + DI+ DG+ Sbjct: 28 EEEIREAFRVEDKDGNGYISAAELRHVM-----TNLGEKLTDEE-VDEMIREADIDGDGQ 81 Query: 150 LTLEEFINGMA 160 + EEF+ M Sbjct: 82 VNYEEFVQMMT 92 >2RO9-A nrPDB Length = 69 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 6/70 (8%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E++LK F+++D D NG I EL + N + L+ EE ++ + + D++ DG+ Sbjct: 3 EEELKEAFRVFDKDQNGFISAAELRHVMT-----NLGEKLTDEE-VDEMIREADVDGDGQ 56 Query: 150 LTLEEFINGM 159 + EEF+ M Sbjct: 57 INYEEFVKVM 66 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 13/67 (19%), Positives = 35/67 (52%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 + + + + + FD +++GF+ E + + ++ ++++ + D DG+G I+ E Sbjct: 2 SEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEE 61 Query: 113 LLDMFMA 119 + + MA Sbjct: 62 FVKVMMA 68 >3AKA-A nrPDB Length = 166 Score = 35.4 bits (80), Expect = 0.018, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 9/81 (11%) Query: 90 EQKLKWYFKLYDADGNGSIDKNE--------LLDMFMAVQALNGQQTLSPEEFINLVFHK 141 E+++ F +D DGNG ID+++ L + +A ++ GQ E + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 142 I-DINNDGELTLEEFINGMAK 161 I D + D +T EEF+ G K Sbjct: 63 IADRDGDQRITREEFVTGAVK 83 >2PMY-A nrPDB Length = 91 Score = 35.4 bits (80), Expect = 0.018, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 8/68 (11%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L+ F DA+ +G +++ E +AL + + P + VF ++D + DG +T Sbjct: 28 RLRSVFAACDANRSGRLEREEF-------RALCTELRVRPAD-AEAVFQRLDADRDGAIT 79 Query: 152 LEEFINGM 159 +EF G Sbjct: 80 FQEFARGF 87 >1TNP-A nrPDB Length = 90 Score = 35.4 bits (80), Expect = 0.018, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 6/83 (7%) Query: 79 AAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV 138 A + E+M + K F ++DADG G I EL V + GQ E ++ + Sbjct: 8 AEARAFLSEEMIAEFKAAFDMFDADGGGDISTKEL----GTVMRMLGQNPTKEE--LDAI 61 Query: 139 FHKIDINNDGELTLEEFINGMAK 161 ++D + G + EEF+ M + Sbjct: 62 IEEVDEDGSGTIDFEEFLVMMVR 84 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 16/70 (22%), Positives = 33/70 (47%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L+++ ++ FD + G + E + ++ Q +++L + D DG+G+I Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 73 Query: 109 DKNELLDMFM 118 D E L M + Sbjct: 74 DFEEFLVMMV 83 >2HPS-A nrPDB Length = 186 Score = 35.4 bits (80), Expect = 0.020, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 42 TLLGLQGLNQKANKHIDQV--YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKL 99 +LL ++G +KA I + Y+ DT+KDG+V EF A + + + + K F Sbjct: 88 SLLKMKG-EEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNT 146 Query: 100 YDADGNGSIDKNELL 114 D + NG I ++E L Sbjct: 147 LDFNKNGQISRDEFL 161 Score = 33.1 bits (74), Expect = 0.098, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 9 GDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 G++KA+ ++ + Y + G +L EFK L G + +K I +NT D NK Sbjct: 94 GEEKAMAVIQSLIMYDCIDTD-KDGYVSLPEFKAFLQAVGPDLTDDKAI-TCFNTLDFNK 151 Query: 69 DGFVDFLEFIAAVN 82 +G + EF+ VN Sbjct: 152 NGQISRDEFLVTVN 165 >3O4Y-A nrPDB Length = 196 Score = 35.0 bits (79), Expect = 0.021, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 54/105 (51%), Gaps = 12/105 (11%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWY-FKLYDADGNGSIDKNELL 114 + D + + D++ G +D+ EF+AA I + ++ +KL + F+++D D +G I EL Sbjct: 91 NFDLLLDQIDSDGSGNIDYTEFLAAA--IDRRQLSKKLIYCAFRVFDVDNDGEITTAELA 148 Query: 115 DMFMAVQALNGQQTLS-PEEFINLV---FHKIDINNDGELTLEEF 155 + NG + + E +N V ++D N DG++ EF Sbjct: 149 HVL-----FNGNKRGNITERDVNQVKKMIREVDKNGDGKIDFYEF 188 Score = 26.2 bits (56), Expect = 9.5, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 14/105 (13%) Query: 80 AVNLIMQEKME---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 A+ +I Q+ + QKLK F D +G G+I K +L + L + P F + Sbjct: 41 AMTIIAQQSNDYDVQKLKAAFLHLDEEGKGNITKLQL------RKGLERSGLMLPPNF-D 93 Query: 137 LVFHKIDINNDGELTLEEF----INGMAKDQDLLEIVYKSFDFSN 177 L+ +ID + G + EF I+ + L+ ++ FD N Sbjct: 94 LLLDQIDSDGSGNIDYTEFLAAAIDRRQLSKKLIYCAFRVFDVDN 138 >2M5E-A nrPDB Length = 73 Score = 35.0 bits (79), Expect = 0.022, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 6/71 (8%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 E++L FK++D DGNG I EL + N + L+ +E ++ + + DI+ DG Sbjct: 7 EEELIEAFKVFDRDGNGLISAAELRHVMT-----NLGEKLTDDE-VDEMIREADIDGDGH 60 Query: 150 LTLEEFINGMA 160 + EEF+ M Sbjct: 61 INYEEFVRMMV 71 >2JOJ-A nrPDB Length = 77 Score = 35.0 bits (79), Expect = 0.022, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 38/68 (55%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L+++ + I + ++ FDTNK G +D+ E A+ + + + ++ YD +GNG I Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYI 60 Query: 109 DKNELLDM 116 ++ LD+ Sbjct: 61 GFDDFLDI 68 >1F55-A nrPDB Length = 77 Score = 35.0 bits (79), Expect = 0.023, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 8/78 (10%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF-INLVFHKID 143 + E+ + K F L+D D NGSI +EL + ++ LSP E +N + ++ID Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSL-------GLSPSEAEVNDLMNEID 56 Query: 144 INNDGELTLEEFINGMAK 161 ++ + ++ EF+ M++ Sbjct: 57 VDGNHQIEFSEFLALMSR 74 >5D43-A nrPDB Length = 178 Score = 35.0 bits (79), Expect = 0.026, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 18/136 (13%) Query: 32 SGLQTLHEFKTL---LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK 88 SG + E K LG + ++ K I +V D G + F +F+A + M EK Sbjct: 45 SGTIDVKELKVAMRALGFEPRKEEMKKMISEV----DKEATGKISFNDFLAVMTQKMAEK 100 Query: 89 -MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEFINLVFHKIDIN 145 ++++ F+L+D D G I F ++ + + ++L+ EE ++ + D + Sbjct: 101 DTKEEILKAFRLFDDDETGKIS-------FKNLKRVANELGESLTDEELQEMI-DEADRD 152 Query: 146 NDGELTLEEFINGMAK 161 DGE+ EEF+ M K Sbjct: 153 GDGEVNEEEFLKIMKK 168 Score = 33.1 bits (74), Expect = 0.081, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E +Q+++ F L+D+DG+G+ID EL +A++AL + +E + + ++D Sbjct: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELK---VAMRALGFE---PRKEEMKKMISEVDK 78 Query: 145 NNDGELTLEEFINGMAK---DQDLLEIVYKSF 173 G+++ +F+ M + ++D E + K+F Sbjct: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 >4L9M-A nrPDB Length = 559 Score = 35.0 bits (79), Expect = 0.026, Method: Compositional matrix adjust. Identities = 17/77 (22%), Positives = 37/77 (48%), Gaps = 9/77 (11%) Query: 47 QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNG 106 + +++ + +D V+ +D ++DG++ EF EK+ + F + D D G Sbjct: 417 KTISKHVQRMVDSVFKNYDHDQDGYISQEEF---------EKIAASFPFSFCVMDKDREG 467 Query: 107 SIDKNELLDMFMAVQAL 123 I ++E+ FM ++ Sbjct: 468 LISRDEITAYFMRASSI 484 >1ZMZ-A nrPDB Length = 98 Score = 34.7 bits (78), Expect = 0.026, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 43/77 (55%), Gaps = 6/77 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ +Q+++ F L+DADG G+ID EL +A++AL + +E I + +ID Sbjct: 25 LTEEQKQEIREAFDLFDADGTGTIDVKELK---VAMRALGFE---PKKEEIKKMISEIDK 78 Query: 145 NNDGELTLEEFINGMAK 161 G++ +F+ M + Sbjct: 79 EGTGKMNFGDFLTVMTQ 95 >2KSZ-A nrPDB Length = 76 Score = 34.7 bits (78), Expect = 0.027, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + + FD + DG + E + + Q E++L+ DADGNG+I+ +E L + Sbjct: 14 EAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSL 71 Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 6/78 (7%) Query: 84 IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKID 143 I+ E+ K F L+D DG+G I EL +++L+ T EE + + ++D Sbjct: 3 ILSEEQIVDFKEAFGLFDKDGDGCITVEELA---TVIRSLDQNPT---EEELQDMISEVD 56 Query: 144 INNDGELTLEEFINGMAK 161 + +G + +EF++ MAK Sbjct: 57 ADGNGTIEFDEFLSLMAK 74 >3LCP-C nrPDB Length = 93 Score = 34.7 bits (78), Expect = 0.028, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 7/85 (8%) Query: 78 IAAVNLIMQEKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQT---LSPEE 133 + +N E Q+L+ YFK++D DGN +D EL V G + +S +E Sbjct: 4 MGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDE 63 Query: 134 FINL---VFHKIDINNDGELTLEEF 155 IN+ V D NNDG + EF Sbjct: 64 LINIIDGVLRDDDKNNDGYIDYAEF 88 >5JOJ-A nrPDB Length = 97 Score = 34.7 bits (78), Expect = 0.029, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMF-MAVQALNGQQTLSPEEFINLVFHKIDI 144 +E ME L+ F D DGNG I NEL D+F A L G + E + D+ Sbjct: 9 EEMME--LREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRV---REITENLMATGDL 63 Query: 145 NNDGELTLEEFI 156 + DG ++ +EFI Sbjct: 64 DQDGRISFDEFI 75 >4YGB-B nrPDB Length = 104 Score = 34.7 bits (78), Expect = 0.032, Method: Compositional matrix adjust. Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%) Query: 85 MQEKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQT---LSPEEFINL--- 137 M E Q+L+ YFK++D DGN +D EL V G + +S +E IN+ Sbjct: 22 MLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 81 Query: 138 VFHKIDINNDGELTLEEF 155 V D NNDG + EF Sbjct: 82 VLRDDDKNNDGYIDYAEF 99 >1Q80-A nrPDB Length = 174 Score = 34.7 bits (78), Expect = 0.032, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 8/68 (11%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 +E L +F+ D + + +I ++E +F + L+ +T++P F ID NNDG Sbjct: 92 VEGPLPLFFRAVDTNEDNNISRDEY-GIFFGMLGLD--KTMAPASF-----DAIDTNNDG 143 Query: 149 ELTLEEFI 156 L+LEEF+ Sbjct: 144 LLSLEEFV 151 >2VRG-A nrPDB Length = 124 Score = 34.7 bits (78), Expect = 0.033, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 79 AAVNLIMQEKMEQKLK-WYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT---LSPEEF 134 +N E Q+L+ YFK++D DGN +D EL V G + +S +E Sbjct: 36 GVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDEL 95 Query: 135 INL---VFHKIDINNDGELTLEEFINGM 159 IN+ V D NNDG + EF + Sbjct: 96 INIIDGVLRDDDKNNDGYIDYAEFAKSL 123 >5JOL-A nrPDB Length = 82 Score = 34.3 bits (77), Expect = 0.035, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMF-MAVQALNGQQTLSPEEFINLVFHKIDI 144 +E ME L+ F D DGNG I NEL D+F A L G + E + D+ Sbjct: 9 EEMME--LREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRV---REITENLMATGDL 63 Query: 145 NNDGELTLEEFI 156 + DG ++ +EFI Sbjct: 64 DQDGRISFDEFI 75 >3A4U-B nrPDB Length = 143 Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 79 AAVNLIMQEKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQT---LSPEEF 134 +N E Q+L+ YFK++D DGN +D EL V G + +S +E Sbjct: 55 GVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDEL 114 Query: 135 INL---VFHKIDINNDGELTLEEFINGM 159 IN+ V D NNDG + EF + Sbjct: 115 INIIDGVLRDDDKNNDGYIDYAEFAKSL 142 >6IIE-A nrPDB Length = 93 Score = 34.3 bits (77), Expect = 0.044, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNE----LLDMFMAVQALNGQQT-LSPEEFINLVFHKI 142 + E KL++ FKLYD D NG +D +E +L M + L+ + L P + + +I Sbjct: 6 RPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRP--ILQEMMKEI 63 Query: 143 DINNDGELTLEEFINGMAKDQDLL 166 D + G ++ E++ A LL Sbjct: 64 DYDGSGSVSQAEWVRAGATTVPLL 87 >4Q57-A nrPDB Length = 65 Score = 33.9 bits (76), Expect = 0.049, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 29/58 (50%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 6 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 63 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 6/69 (8%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F L+D DG+G+I EL + ++ GQ E + + +++D + +G + Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMINEVDADGNGTID 56 Query: 152 LEEFINGMA 160 EF+ MA Sbjct: 57 FPEFLTMMA 65 >5H7D-E nrPDB Length = 120 Score = 33.9 bits (76), Expect = 0.052, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 29/58 (50%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 60 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 117 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q K F L+D DG+G+I EL + ++ GQ E + + +++D + +G + Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPTEAE--LQDMINEVDADGNGTI 109 Query: 151 TLEEFINGMAK 161 EF+ MA+ Sbjct: 110 DFPEFLTMMAR 120 >2I18-A nrPDB Length = 64 Score = 33.9 bits (76), Expect = 0.052, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 LK +KL D DG+G + K E+ F +G + ++ + K D N DG +TL Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKK----HGIEKVAEQ------VMKADANGDGYITL 56 Query: 153 EEFI 156 EEF+ Sbjct: 57 EEFL 60 >2BEC-A nrPDB Length = 202 Score = 33.9 bits (76), Expect = 0.052, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 7/73 (9%) Query: 92 KLKWYFKLYDADGNGSIDKNELLD---MFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 KL + F+LYD D +G I ++E+L + + VQ Q E + + D + DG Sbjct: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL----ENIADRTVQEADEDGDG 170 Query: 149 ELTLEEFINGMAK 161 ++ EF + K Sbjct: 171 AVSFVEFTKSLEK 183 >1YX7-A nrPDB Length = 83 Score = 33.9 bits (76), Expect = 0.055, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 38/76 (50%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M K++ +L+ FK DA+G+G + EL + + A +E + D Sbjct: 1 MACKVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADK 60 Query: 145 NNDGELTLEEFINGMA 160 N+DG+++ EEF+N A Sbjct: 61 NSDGKISKEEFLNANA 76 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 6/70 (8%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEF------IAAVNLIMQEKMEQKLKWYFKLYDADGN 105 K ++ + D N DG+V LE + A + ++K+++ K+ D + + Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD 63 Query: 106 GSIDKNELLD 115 G I K E L+ Sbjct: 64 GKISKEEFLN 73 >2RO8-A nrPDB Length = 79 Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 30/58 (51%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L++ Sbjct: 14 EAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNL 71 Score = 32.0 bits (71), Expect = 0.18, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 6/70 (8%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F L+D DG+G I EL + ++ GQ E + + +++D + +G + Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSL----GQNPTEAE--LQDMINEVDADGNGTID 64 Query: 152 LEEFINGMAK 161 EF+N MA+ Sbjct: 65 FPEFLNLMAR 74 >5OTJ-D nrPDB Length = 110 Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 M ++ FK +D +G+G I +EL D AL + S +E + + +ID + DG Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTD------ALRTLGSTSADE-VQRMMAEIDTDGDG 53 Query: 149 ELTLEEFINGMAKDQDLLEIVYKSF 173 + EFI+ + L++ V K F Sbjct: 54 FIDFNEFISFCNANPGLMKDVAKVF 78 Score = 30.0 bits (66), Expect = 0.71, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 46 LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 L+ L + + ++ DT+ DGF+DF EFI+ N Sbjct: 29 LRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFCN 65 >3IFK-A nrPDB Length = 90 Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 29/58 (50%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 14 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 71 >3E3R-A nrPDB Length = 204 Score = 33.1 bits (74), Expect = 0.079, Method: Compositional matrix adjust. Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 6/100 (6%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 V +D N G +D EF+ A+ M + E + F D G+G + ++L ++ Sbjct: 78 VCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSG 137 Query: 120 ---VQALNGQQTLSPEEFINLVFHKIDIN-NDGELTLEEF 155 + +G+ T +E + D + DG++TL EF Sbjct: 138 RAHPKVRSGEWT--EDEVLRRFLDNFDSSEKDGQVTLAEF 175 Score = 29.6 bits (65), Expect = 0.87, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q L +F+ D DG+ S+D +E Q L + + V K D N G L Sbjct: 37 QGLARFFRQLDRDGSRSLDADEFR------QGLAKLGLVLDQAEAEGVCRKWDRNGSGTL 90 Query: 151 TLEEFINGM 159 LEEF+ + Sbjct: 91 DLEEFLRAL 99 >4V3P-LQ nrPDB Length = 304 Score = 32.7 bits (73), Expect = 0.100, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 14 VPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD 73 V TQ+TH +++ F +++ Q +++ + L NQ NK+ Y F TNKD Sbjct: 8 VKTQKTHAYFKRFQVKFKRRRQGKTDYRARIRL--TNQDKNKYNTPKYR-FVTNKDITAQ 64 Query: 74 FLEFIAAVNLIMQEKMEQKLKWY 96 + A +++M +L Y Sbjct: 65 IVYATIAGDIVMAAAYSHELPRY 87 >4DS7-A nrPDB Length = 147 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ-EKME 90 SG + E T++ GL+ + + + N D + + ++F EF+A ++ ++ E Sbjct: 25 SGSISASELATVMRSLGLS-PSEAEVADLMNEIDVDGNHAIEFSEFLALMSRQLKCNDSE 83 Query: 91 QKLKWYFKLYDADGNGSIDKNEL 113 Q+L FK++D +G+G I EL Sbjct: 84 QELLEAFKVFDKNGDGLISAAEL 106 >3JBH-C nrPDB Length = 156 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 18/84 (21%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQA--------------LNGQQTLSPEEFIN 136 +K + +F++YD +G G ID +L D+ ++ G++ L+ EEF+ Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNGGSDKRGEKKLTLEEFLP 69 Query: 137 LVFHKIDINNDGEL-TLEEFINGM 159 + I + E+ TLE+F+ G+ Sbjct: 70 IFSQ---IKKEKEVGTLEDFMEGL 90 >2LVK-A nrPDB Length = 77 Score = 32.0 bits (71), Expect = 0.17, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 ++ FK +D +G+G I +EL D AL + S +E + + +ID + DG + Sbjct: 4 MERIFKRFDTNGDGKISLSELTD------ALRTLGSTSADE-VQRMMAEIDTDGDGFIDF 56 Query: 153 EEFINGMAKDQDLLEIVYKSF 173 EFI+ + L++ V K F Sbjct: 57 NEFISFCNANPGLMKDVAKVF 77 Score = 29.6 bits (65), Expect = 0.96, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 L+ L + + ++ DT+ DGF+DF EFI+ N Sbjct: 27 ALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFCN 64 >5XOP-A nrPDB Length = 66 Score = 32.0 bits (71), Expect = 0.18, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 31/63 (49%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + ++ D N DG V + E A V+ K EQ L+ FK D DG+G ID E + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKFY 62 Query: 118 MAV 120 ++ Sbjct: 63 GSI 65 Score = 30.0 bits (66), Expect = 0.74, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 FK D +G+G++ E+ ++ ++ + E+ + L+F ID + DG + EEF Sbjct: 6 FKEIDVNGDGAVSYEEVKAF------VSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEF 58 Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 28/42 (66%), Gaps = 5/42 (11%) Query: 138 VFHKIDINNDGELTLEE---FING--MAKDQDLLEIVYKSFD 174 +F +ID+N DG ++ EE F++ K++ LL++++KS D Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSID 46 >4P5W-A nrPDB Length = 411 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 25/132 (18%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDAD 103 L + G +Q K ++ + D KDG + F EF+A +++ + F+L+D Sbjct: 67 LNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAP--DALFMVAFQLFDKA 124 Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSP-------EEFINLVFHKIDINNDGELTLEEFI 156 G G + F V+ + GQ T+ EF+ L F K LT EF Sbjct: 125 GKGEV-------TFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGK---ERKRHLTYAEFT 174 Query: 157 NGMAKDQDLLEI 168 Q LLEI Sbjct: 175 ------QFLLEI 180 >1OZS-A nrPDB Length = 73 Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust. Identities = 17/70 (24%), Positives = 33/70 (47%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 K+ + + ++ FD N DG++D E + + E ++ K D + +G ID + Sbjct: 4 KSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYD 63 Query: 112 ELLDMFMAVQ 121 E L+ V+ Sbjct: 64 EFLEFMKGVE 73 Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M+ K E++L F+++D + +G ID EL M A +T++ ++ I + D Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG-----ETITEDD-IEELMKDGDK 54 Query: 145 NNDGELTLEEFINGM 159 NNDG + +EF+ M Sbjct: 55 NNDGRIDYDEFLEFM 69 >4WPX-A nrPDB Length = 177 Score = 31.2 bits (69), Expect = 0.29, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 80 AVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVF 139 A LI Q +L+ F+L+D DG G I +++L + V G P+ I + Sbjct: 100 AGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQV----GNNI--PDADIQAMI 153 Query: 140 HKIDINNDGELTLEEFINGM 159 + D N G + +EF+ M Sbjct: 154 EEFDSNGKGGVDEDEFLRLM 173 >3FWC-A nrPDB Length = 161 Score = 31.2 bits (69), Expect = 0.33, Method: Compositional matrix adjust. Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 43/145 (29%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN-------------------------- 82 L ++ + I + ++ FD N DGF+D+ E A+ Sbjct: 17 LLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLM 76 Query: 83 ------LIMQEKMEQK-----LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 ++M EK+ ++ +K F+L+D D G I L + A +TL+ Sbjct: 77 KYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRV-----AKELGETLTD 131 Query: 132 EEFINLVFHKIDINNDGELTLEEFI 156 EE ++ + D++ DGE+ EFI Sbjct: 132 EELRAMI-EEFDLDGDGEINENEFI 155 Score = 27.3 bits (59), Expect = 5.1, Method: Compositional matrix adjust. Identities = 16/81 (19%), Positives = 37/81 (45%) Query: 34 LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKL 93 L +F ++G + L + I + + FD + G + + + +++L Sbjct: 75 LMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEEL 134 Query: 94 KWYFKLYDADGNGSIDKNELL 114 + + +D DG+G I++NE + Sbjct: 135 RAMIEEFDLDGDGEINENEFI 155 >5ZOR-A nrPDB Length = 149 Score = 31.2 bits (69), Expect = 0.33, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 8/87 (9%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 +++++ F L+DADG+G+ID E M +A++ L G L P + + ++ N +G Sbjct: 6 DEQIREAFNLFDADGSGAIDAEE---MALAMKGL-GFGDL-PRDEVERTVRSMNTNANGL 60 Query: 150 LTLEEF---INGMAKDQDLLEIVYKSF 173 + EF + +D E V K+F Sbjct: 61 IEYGEFERMVKSRMAQKDSPEEVLKAF 87 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 21/109 (19%), Positives = 45/109 (41%), Gaps = 1/109 (0%) Query: 14 VPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD 73 +P E R+ M +GL EF+ ++ + + + + + + + FD +K G + Sbjct: 41 LPRDEVERTVRS-MNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKIS 99 Query: 74 FLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 F L+ + + L+ D DG+G + E + M ++ Sbjct: 100 FANLKEVAKLLGENPGDDVLQEMIAEADEDGDGEVSFEEFKSVMMQMRG 148 >1Y1X-A nrPDB Length = 191 Score = 31.2 bits (69), Expect = 0.34, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 6/65 (9%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q+L +F+ D DG+G+I EL A+ + +L+ E + H D N+ GE+ Sbjct: 27 QELMEWFRAVDTDGSGAISVPELN---AALSSAGVPFSLATTE---KLLHMYDKNHSGEI 80 Query: 151 TLEEF 155 T +EF Sbjct: 81 TFDEF 85 Score = 29.6 bits (65), Expect = 0.93, Method: Compositional matrix adjust. Identities = 30/140 (21%), Positives = 59/140 (42%), Gaps = 14/140 (10%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 QE W+R + SG ++ E L G+ +++ + +D N G + F E Sbjct: 27 QELMEWFRAVDTD-GSGAISVPELNAALSSAGVPFSLAT-TEKLLHMYDKNHSGEITFDE 84 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 F + I+ ++ F+ D+ G+G +D NE+ ++ +G Q E+ Sbjct: 85 FKDLHHFIL------SMREGFRKRDSSGDGRLDSNEVRAALLS----SGYQV--SEQTFQ 132 Query: 137 LVFHKIDINNDGELTLEEFI 156 + K D G L ++++ Sbjct: 133 ALMRKFDRQRRGSLGFDDYV 152 >4I5L-B nrPDB Length = 413 Score = 30.8 bits (68), Expect = 0.40, Method: Compositional matrix adjust. Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 20/116 (17%) Query: 53 ANKHIDQVYNTFDTN-----KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 + K ID++++ T K+G + + +F+ + +K ++++F+ D DG+G+ Sbjct: 229 STKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGA 288 Query: 108 IDKNELLDMF---------MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 + EL + MA++AL Q L + ++LV +G++TL++ Sbjct: 289 LSMFELEYFYEEQCRRLDSMAIEALPFQDCLC--QMLDLV----KPRTEGKITLQD 338 >4MEW-A nrPDB Length = 356 Score = 30.0 bits (66), Expect = 0.67, Method: Compositional matrix adjust. Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 20/116 (17%) Query: 53 ANKHIDQVYNTFDTN-----KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 + K ID++++ T K+G + + +F+ + +K ++++F+ D DG+G+ Sbjct: 221 STKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGA 280 Query: 108 IDKNELLDMF---------MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 + EL + MA++AL Q L + ++LV +G++TL++ Sbjct: 281 LSMFELEYFYEEQCRRLDSMAIEALPFQDCLC--QMLDLV----KPRTEGKITLQD 330 >2E30-A nrPDB Length = 195 Score = 30.0 bits (66), Expect = 0.72, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKI---DINNDG 148 KL + F+LYD D + I ++ELL + + +N +S E+ ++ I D + D Sbjct: 114 KLHFAFRLYDLDKDEKISRDELLQVLRMMVGVN----ISDEQLGSIADRTIQEADQDGDS 169 Query: 149 ELTLEEFINGMAK 161 ++ EF+ + K Sbjct: 170 AISFTEFVKVLEK 182 >2KQY-A nrPDB Length = 108 Score = 30.0 bits (66), Expect = 0.76, Method: Compositional matrix adjust. Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD------FLEFIAAVNLIMQEKMEQKL 93 +K+ GL+ K I +V+ D +K GF++ FL+ ++ ++ + Sbjct: 26 YKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVL---TSAET 82 Query: 94 KWYFKLYDADGNGSIDKNELLDMFMA 119 K + D DG+G I E + A Sbjct: 83 KAFLAAGDTDGDGKIGVEEFQSLVKA 108 >5I2L-A nrPDB Length = 120 Score = 30.0 bits (66), Expect = 0.80, Method: Compositional matrix adjust. Identities = 17/74 (22%), Positives = 34/74 (45%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 ++K K +++++ +D +DGF+D +E + + + LK K D D + + Sbjct: 25 FSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKL 84 Query: 109 DKNELLDMFMAVQA 122 E L +F A Sbjct: 85 SFREFLLIFRKAAA 98 >5TBY-E nrPDB Length = 166 Score = 29.6 bits (65), Expect = 0.90, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 Q+ K F + D + +G IDKN+L D F A+ +N Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVN 60 >4D1E-A nrPDB Length = 876 Score = 29.6 bits (65), Expect = 0.95, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 35 QTLHEFKTLL---GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +T++E +T + +G+ Q+ +N FD K+G +D +F A + + + E Sbjct: 715 RTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEA 774 Query: 92 KLKWYFKLYDADGNGSIDKNELLD 115 + L D +G G++ +D Sbjct: 775 EFARIMTLVDPNGQGTVTFQSFID 798 >2I08-A nrPDB Length = 78 Score = 29.6 bits (65), Expect = 0.95, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 32/72 (44%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L ++ + ++ +D + DG + E + + E +L+ DADGNG+I Sbjct: 4 LTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTI 63 Query: 109 DKNELLDMFMAV 120 D E L M + Sbjct: 64 DFPEFLTMMARI 75 Score = 26.9 bits (58), Expect = 5.6, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 G T E T++ GLN + D + N D + +G +DF EF+ + IM+ Sbjct: 25 GTITTKELGTVMRSLGLNPTEAELQDMI-NEVDADGNGTIDFPEFLTMMARIMK 77 >4XOX-A nrPDB Length = 404 Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust. Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 6/73 (8%) Query: 30 YPSGLQTLHEFKTLL--GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 + G + L+ +T++ + L+ K N+ ++ T+D ++DGFV +++ E Sbjct: 184 FAGGGEELYWSQTMMFDAMGALSTKYNETPEKASRTYDADRDGFV----ISGGGGMVVVE 239 Query: 88 KMEQKLKWYFKLY 100 ++E L K+Y Sbjct: 240 ELEHALARGAKIY 252 >2WCE-A nrPDB Length = 95 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 20/30 (66%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 ID+++ D N+D VDF EFI+ V + ++ Sbjct: 57 IDEIFQGLDANQDEQVDFQEFISMVAIALK 86 >5HYD-A nrPDB Length = 99 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 18/31 (58%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 QK + +D++ D NKD VDF EF+ V Sbjct: 49 QKETQLVDKIVQDLDANKDNEVDFNEFVVMV 79 >1TIZ-A nrPDB Length = 67 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 +V+ FD NKDG + EF ++ + +F+ D DGNG ++ +E Sbjct: 5 RVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEF 59 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 K F+ +D + +G + +E ++ +A Q+ + F +ID++ +GEL + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVK------FFEEIDVDGNGELNAD 57 Query: 154 EFINGMAK 161 EF + + K Sbjct: 58 EFTSCIEK 65 >1BU3-A nrPDB Length = 109 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWY 96 +K GL K+ I + + D +K GF++ E F+ + + + + K + Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 97 FKLYDADGNGSIDKNE 112 K D+DG+G+I +E Sbjct: 87 LKAGDSDGDGAIGVDE 102 >5XND-A nrPDB Length = 114 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWYFKLYDADG 104 GL+ K+ + + + D +K GF++ E F+ + + + K + K D+DG Sbjct: 40 GLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDG 99 Query: 105 NGSIDKNELLDM 116 +G I +E M Sbjct: 100 DGKIGIDEFAAM 111 >1S6J-A nrPDB Length = 87 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 27/56 (48%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 +++ DT+ G + F E + + E ME ++K D D +G+ID E + Sbjct: 27 ELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFI 82 Score = 26.6 bits (57), Expect = 7.5, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 10/76 (13%) Query: 85 MQEKMEQK----LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 M E++ ++ LK FK+ D D +G+I +EL D V G + + E I + Sbjct: 13 MAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRV----GSELMESE--IKDLMD 66 Query: 141 KIDINNDGELTLEEFI 156 DI+ G + EFI Sbjct: 67 AADIDKSGTIDYGEFI 82 >1QLS-A nrPDB Length = 99 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 89 MEQKLKWYFKLYDADGNGS-IDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 +E + + K DGN + I K E L +FM + Q ++ + K+D+++D Sbjct: 12 IESLIAIFQKHAGRDGNNTKISKTEFL-IFMNTELAAFTQNQKDPGVLDRMMKKLDLDSD 70 Query: 148 GELTLEEFIN 157 G+L +EF+N Sbjct: 71 GQLDFQEFLN 80 >5CSF-A nrPDB Length = 95 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 +D+V T D + DG DF EF+A V ++ Sbjct: 57 VDKVMETLDNDGDGECDFQEFMAFVAMV 84 >5VE9-A nrPDB Length = 91 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 10/23 (43%), Positives = 18/23 (78%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVN 82 V + FD + DG++D+ EF+AA++ Sbjct: 68 VADIFDRDGDGYIDYYEFVAALH 90 Score = 27.7 bits (60), Expect = 3.8, Method: Compositional matrix adjust. Identities = 10/21 (47%), Positives = 17/21 (80%) Query: 139 FHKIDINNDGELTLEEFINGM 159 F +ID + DG++T +EFI+G+ Sbjct: 33 FRRIDKDQDGKITRQEFIDGI 53 >2Y5I-A nrPDB Length = 99 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 ++QK ++++ N D+NKD VDF EF+ V Sbjct: 47 MSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLV 79 >1BOD-A nrPDB Length = 74 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 8/70 (11%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMA--VQALNGQQTLSPEEFINLVFHKIDIN 145 K ++LK F+ YD +G+G + K EL + L G TL + +F ++D N Sbjct: 2 KSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTL------DELFEELDKN 55 Query: 146 NDGELTLEEF 155 DGE++ EEF Sbjct: 56 GDGEVSFEEF 65 >1MO0-A nrPDB Length = 275 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 17/29 (58%), Gaps = 4/29 (13%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMME 29 +G GK+ +G+Q QE H W R F+ E Sbjct: 189 IGTGKTASGEQ----AQEVHEWIRAFLKE 213 >2LUC-A nrPDB Length = 105 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 3/35 (8%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 NQK +D++ DTN DG +DF EF+ NLI Sbjct: 53 NQKDPGVLDRMMKKLDTNSDGQLDFSEFL---NLI 84 Score = 26.6 bits (57), Expect = 9.3, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 87 EKMEQKLKWYFKLYDA-DG-NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 E+ + L F+ Y DG N ++ K E L FM + + ++ + K+D Sbjct: 11 ERCIESLIAVFQKYAGKDGYNYTLSKTEFLS-FMNTELAAFTKNQKDPGVLDRMMKKLDT 69 Query: 145 NNDGELTLEEFIN 157 N+DG+L EF+N Sbjct: 70 NSDGQLDFSEFLN 82 >1A75-A nrPDB Length = 108 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWY 96 +K GL+ K+ I + + D +K GF++ E F+ + + + K + Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 97 FKLYDADGNGSIDKNELLDMFMA 119 K D+DG+G+I E + + A Sbjct: 86 LKAGDSDGDGAIGVEEWVALVKA 108 >4P5X-A nrPDB Length = 315 Score = 28.1 bits (61), Expect = 3.1, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 18/91 (19%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 D KDG + + EF+A +++ + F+L+D GNG + F V+ + Sbjct: 69 DQTKDGLISYQEFLAFESVLCAP--DSMFIVAFQLFDKSGNGEV-------TFENVKEIF 119 Query: 125 GQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 GQ ++ H I N D E F Sbjct: 120 GQ---------TIIHHHIPFNWDCEFIRLHF 141 >1CB1-A nrPDB Length = 78 Score = 28.1 bits (61), Expect = 3.1, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 12/74 (16%) Query: 87 EKMEQKLKWYFKLYDA---DGNGSIDKNELLDMFMA--VQALNGQQTLSPEEFINLVFHK 141 +K +LK F+ Y A D N + K EL + A L G +TL + +F + Sbjct: 3 QKSPAELKSIFEKYAAKEGDPN-QLSKEELKQLIQAEFPSLLKGPRTL------DDLFQE 55 Query: 142 IDINNDGELTLEEF 155 +D N DGE++ EEF Sbjct: 56 LDKNGDGEVSFEEF 69 >5H53-B nrPDB Length = 146 Score = 27.7 bits (60), Expect = 3.3, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 Q+ K F + D + +G IDK +L D F A+ LN Sbjct: 5 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLN 38 >1TRF-A nrPDB Length = 76 Score = 27.7 bits (60), Expect = 3.4, Method: Compositional matrix adjust. Identities = 16/68 (23%), Positives = 32/68 (47%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L+++ ++ FD + G + E + ++ Q +++L + D DG+G+I Sbjct: 3 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 62 Query: 109 DKNELLDM 116 D E L M Sbjct: 63 DFEEFLVM 70 >5Z09-A nrPDB Length = 409 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 141 KIDINNDGELTLEEFINGMAKDQDLLEIVYKSF 173 KI I+ GEL L + IN MAKD + I Y+ + Sbjct: 173 KISISERGELELTDAINLMAKDHRVKVIEYEGY 205 >3MSE-B nrPDB Length = 180 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 9/66 (13%) Query: 96 YFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 ++KL D + NGS+ E+ + +V G + IN + +DIN+ G +T EF Sbjct: 45 FYKL-DTNHNGSLSHREIYTVLASV----GIKKWD----INRILQALDINDRGNITYTEF 95 Query: 156 INGMAK 161 + G + Sbjct: 96 MAGCYR 101 >2KGR-A nrPDB Length = 111 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 127 QTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 Q+ P+ + +++ DI+ DG+LT EEFI M Sbjct: 42 QSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 74 >1ZFS-A nrPDB Length = 93 Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 QK +D++ D N DG VDF EF+ V Sbjct: 48 QKDADAVDKIMKELDENGDGEVDFQEFVVLV 78 >2BL0-B nrPDB Length = 145 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 6/61 (9%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F+ D +GNG+I + EL + LN L+ E L+ ++ ++ DG + E F+ Sbjct: 82 FRALDKEGNGTIQEAELRQLL-----LNLGDALTSSEVEELM-KEVSVSGDGAINYESFV 135 Query: 157 N 157 + Sbjct: 136 D 136 >4NQG-A nrPDB Length = 197 Score = 27.3 bits (59), Expect = 4.3, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 10/60 (16%) Query: 97 FKLYDADGNGSIDKNELLDM--FMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 F + D DGNGS+ +E + +Q GQ F D++ DG+L ++E Sbjct: 120 FDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQ--------CEATFAHCDLDGDGKLDVDE 171 >1OQP-A nrPDB Length = 77 Score = 27.3 bits (59), Expect = 4.3, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F+L+D D +G+I + D+ + L + L+ EE ++ + D N+D E+ +EFI Sbjct: 15 FRLFDDDNSGTI---TIKDLRRVAKELG--ENLTEEELQEMI-AEADRNDDNEIDEDEFI 68 Query: 157 NGMAK 161 M K Sbjct: 69 RIMKK 73 >4NSC-A nrPDB Length = 401 Score = 27.3 bits (59), Expect = 4.4, Method: Compositional matrix adjust. Identities = 10/26 (38%), Positives = 16/26 (61%) Query: 130 SPEEFINLVFHKIDINNDGELTLEEF 155 +P+ + F D+N DGE+ +EEF Sbjct: 143 TPQRNFEIAFKMFDLNGDGEVDMEEF 168 Score = 26.9 bits (58), Expect = 6.4, Method: Compositional matrix adjust. Identities = 18/80 (22%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 ++Q+ K D+ + + G + F ++I ++ ++ + FK++D +G+G + Sbjct: 106 ISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTP--QRNFEIAFKMFDLNGDGEV 163 Query: 109 DKNELLDMFMAVQALNGQQT 128 D E F VQ++ QT Sbjct: 164 DMEE----FEQVQSIIRSQT 179 >6MI5-X nrPDB Length = 117 Score = 27.3 bits (59), Expect = 4.6, Method: Compositional matrix adjust. Identities = 23/97 (23%), Positives = 36/97 (37%), Gaps = 29/97 (29%) Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 FD +KDG +D E +AA + F D D +G++D EL Sbjct: 11 AFDPDKDGTIDLKEALAAGS------------AAFDKLDPDKDGTLDAKELKGRVSEAD- 57 Query: 123 LNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 K+D +NDG L +E++ + Sbjct: 58 ----------------LKKLDPDNDGTLDKKEYLAAV 78 >2M8U-A nrPDB Length = 77 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 FK++D DGNG + + L + LN + P + I + ++ D N G + E F+ Sbjct: 17 FKVFDRDGNGYVTVDYLR------KVLNELGDMMPADEIEEMIYEADPQNSGYVQYETFV 70 >3KPX-A nrPDB Length = 198 Score = 27.3 bits (59), Expect = 4.9, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 F ++D DG+GSI LD + ++G +E F D++N G+L ++E Sbjct: 122 FDIFDKDGSGSIS----LDEWKTYGGISG--ICPSDEDAEKTFKHCDLDNSGKLDVDE 173 >1JF0-A nrPDB Length = 195 Score = 27.3 bits (59), Expect = 4.9, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 D V++ FD + G + E+ A + E+ + F+ D D +G +D +E Sbjct: 116 DAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDE----- 170 Query: 118 MAVQALNGQQTLSPE 132 M Q L TL PE Sbjct: 171 MTRQHLGFWYTLDPE 185 >1S36-A nrPDB Length = 195 Score = 27.3 bits (59), Expect = 5.2, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 D V++ FD + G + E+ A + ++ + F+ D D +G +D +E Sbjct: 116 DAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDE----- 170 Query: 118 MAVQALNGQQTLSPE 132 M Q L TL PE Sbjct: 171 MTRQHLGFWYTLDPE 185 >1NSH-A nrPDB Length = 101 Score = 26.9 bits (58), Expect = 5.6, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 3/73 (4%) Query: 87 EKMEQKLKWYFKLYDA-DGNG-SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 E+ + L F+ Y DG+ ++ K E L FM + + ++ + K+D+ Sbjct: 7 ERCIESLIAVFQKYAGKDGHSVTLSKTEFLS-FMNTELAAFTKNQKDPGVLDRMMKKLDL 65 Query: 145 NNDGELTLEEFIN 157 N+DG+L +EF+N Sbjct: 66 NSDGQLDFQEFLN 78 >5US9-A nrPDB Length = 541 Score = 26.9 bits (58), Expect = 5.7, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 19/40 (47%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT 128 +E K++WY + NG+I N+ L M G QT Sbjct: 352 LEYKIQWYQTPQGTNNNGNIISNQPLSMLRDQALFRGNQT 391 >2Q4U-A nrPDB Length = 272 Score = 26.9 bits (58), Expect = 5.8, Method: Compositional matrix adjust. Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 20/121 (16%) Query: 52 KANKHIDQVYNTFDTNKDGFVDF--LEFIAAV--NLIMQEKME--------QKLKWYFKL 99 K +++ D + FD NKDG +D L I A+ N ++Q KM+ + + F Sbjct: 145 KLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAH 204 Query: 100 YDADGNGSIDKNE----LLDMFMAVQ-ALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 YD G+++ E + DM V+ +++G ++F + D+N DG++ E Sbjct: 205 YDVSRTGALEGPEVDGFVKDMMELVRPSISGGDL---DKFRECLLTHCDMNKDGKIQKSE 261 Query: 155 F 155 Sbjct: 262 L 262 >5CA8-A nrPDB Length = 692 Score = 26.9 bits (58), Expect = 6.3, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 14/114 (12%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYF-----KLYDADGNGSIDKNELLDMFMA 119 D +D F D+ + N + E+ +KL+W +++D N LL+ F Sbjct: 361 DLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLC--NTLLEKFEK 418 Query: 120 -VQALNGQ------QTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 + AL G+ +TLS + ++ F ++ G+L+L+E I + KD D + Sbjct: 419 DLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAI 472 >2MBX-A nrPDB Length = 109 Score = 26.9 bits (58), Expect = 7.1, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 9/78 (11%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVD------FLEFIAAVNLIMQEKMEQKLKWYFKLYD 101 GL K+ I +V+ D +K FV+ FL+ +A + + + K + K D Sbjct: 35 GLAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSD---AETKVFLKAGD 91 Query: 102 ADGNGSIDKNELLDMFMA 119 +DG+G I +E M A Sbjct: 92 SDGDGKIGVDEFGAMIKA 109 >2MA2-A nrPDB Length = 81 Score = 26.9 bits (58), Expect = 7.1, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 15/84 (17%) Query: 84 IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ-QTLSPEEFINLVFHKI 142 ++ E +E+ ++ F+ +D DG+G I + E Q + G LS F + Sbjct: 6 LVVEHIEKMVESVFRNFDVDGDGHISQEEF-------QIIRGNFPYLSA-------FGDL 51 Query: 143 DINNDGELTLEEFINGMAKDQDLL 166 D N DG ++ EE ++ + +L Sbjct: 52 DQNQDGCISREEMVSYFLRSSSVL 75 >1M39-A nrPDB Length = 89 Score = 26.6 bits (57), Expect = 7.3, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 9/92 (9%) Query: 72 VDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSID-KNELLDMFMAVQALNGQQTL 129 ++F +F+ + M EK ++++ FKL+D D G I KN + A + L Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKN------LKRVAKELGENL 54 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + EE ++ + D + DGE++ +EF+ M K Sbjct: 55 TDEELQEMI-DEADRDGDGEVSEQEFLRIMKK 85 >2L0P-A nrPDB Length = 94 Score = 26.6 bits (57), Expect = 7.8, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 QK +D+V D N DG VDF E++ V Sbjct: 49 QKDVDAVDKVMKELDENGDGEVDFQEYVVLV 79 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2GGZ-A nrPDB 273 5e-74 2NA0-A nrPDB 213 5e-56 2R2I-A nrPDB 201 1e-52 5T7C-A nrPDB 189 5e-49 1BJF-A nrPDB 188 1e-48 5M6C-E nrPDB 180 4e-46 2L2E-A nrPDB 180 4e-46 2JUL-A nrPDB 178 2e-45 2LCP-A nrPDB 175 1e-44 2JU0-A nrPDB 170 3e-43 3DD4-A nrPDB 170 3e-43 6EPA-A nrPDB 170 4e-43 1S6C-A nrPDB 169 7e-43 1S1E-A nrPDB 168 2e-42 2I94-A nrPDB 165 1e-41 1JBA-A nrPDB 164 3e-41 2D8N-A nrPDB 158 2e-39 4IL1-A nrPDB 150 5e-37 4OY4-A nrPDB 148 1e-36 3U0K-A nrPDB 148 2e-36 3EK4-A nrPDB 146 7e-36 5UKG-A nrPDB 142 9e-35 4I2Y-A nrPDB 138 2e-33 3WFN-B nrPDB 132 9e-32 2N6A-A nrPDB 131 2e-31 6O20-F nrPDB 130 5e-31 2F2P-A nrPDB 129 1e-30 4E53-A nrPDB 126 8e-30 6HCS-A nrPDB 125 9e-30 5I0I-E nrPDB 122 1e-28 2ZFD-A nrPDB 120 3e-28 1CLM-A nrPDB 120 4e-28 5A2H-A nrPDB 120 6e-28 1GGZ-A nrPDB 117 4e-27 1UHN-A nrPDB 117 4e-27 1V1G-A nrPDB 116 8e-27 3HZT-A nrPDB 113 4e-26 4ORC-B nrPDB 113 6e-26 1DTL-A nrPDB 110 6e-25 1DGU-A nrPDB 109 8e-25 5JN2-A nrPDB 108 1e-24 3K21-A nrPDB 108 2e-24 2AAO-A nrPDB 108 2e-24 4JWQ-A nrPDB 108 2e-24 2L1W-A nrPDB 108 2e-24 2LM5-A nrPDB 107 3e-24 1TOP-A nrPDB 107 4e-24 4YZB-A nrPDB 106 8e-24 1S6I-A nrPDB 106 8e-24 3Q5I-A nrPDB 105 1e-23 2TN4-A nrPDB 105 1e-23 4MVF-A nrPDB 105 2e-23 5YPX-A nrPDB 104 2e-23 3KHE-A nrPDB 104 2e-23 5B8I-B nrPDB 104 3e-23 4RGJ-A nrPDB 104 3e-23 2LMV-A nrPDB 103 8e-23 3LIJ-A nrPDB 102 1e-22 2JNF-A nrPDB 102 2e-22 3NCG-A nrPDB 100 4e-22 3PM8-A nrPDB 100 8e-22 3QRX-A nrPDB 98 3e-21 2LAP-A nrPDB 96 1e-20 3L19-A nrPDB 95 2e-20 2LHI-A nrPDB 95 3e-20 2M29-A nrPDB 90 5e-19 2E6W-A nrPDB 90 7e-19 3KF9-A nrPDB 88 2e-18 3AAJ-A nrPDB 87 4e-18 1JFJ-A nrPDB 80 4e-16 2JNX-A nrPDB 78 3e-15 5E1J-A nrPDB 76 8e-15 5MWC-D nrPDB 74 4e-14 4N5X-A nrPDB 74 5e-14 4ZCV-A nrPDB 73 1e-13 5E37-A nrPDB 72 2e-13 2AMI-A nrPDB 70 6e-13 2M7M-A nrPDB 63 1e-10 Sequences not found previously or not previously below threshold: 3O4Y-A nrPDB 104 3e-23 4DS7-A nrPDB 93 7e-20 1LKJ-A nrPDB 89 1e-18 5D43-A nrPDB 88 3e-18 2GGM-A nrPDB 84 4e-17 5ZOR-A nrPDB 82 2e-16 2OBH-A nrPDB 79 1e-15 2BEC-A nrPDB 78 3e-15 2HF5-A nrPDB 77 4e-15 2LHH-A nrPDB 77 4e-15 2KN2-A nrPDB 75 2e-14 1FW4-A nrPDB 74 3e-14 2BL0-C nrPDB 74 5e-14 2KZ2-A nrPDB 73 1e-13 3E3R-A nrPDB 72 1e-13 2E30-A nrPDB 71 3e-13 2ROB-A nrPDB 70 7e-13 2RO9-A nrPDB 70 9e-13 2M5E-A nrPDB 69 1e-12 2N7L-C nrPDB 69 2e-12 2LV7-A nrPDB 68 3e-12 2LC5-A nrPDB 68 3e-12 5VLN-A nrPDB 67 4e-12 2K7C-A nrPDB 66 1e-11 3IFK-A nrPDB 65 2e-11 2B1U-A nrPDB 65 2e-11 5H7D-E nrPDB 64 4e-11 5COC-A nrPDB 64 4e-11 4WPX-A nrPDB 64 5e-11 4GJF-A nrPDB 64 6e-11 1JC2-A nrPDB 63 1e-10 5XOP-A nrPDB 63 1e-10 1JUO-A nrPDB 62 1e-10 5OTJ-D nrPDB 62 2e-10 5MRA-A nrPDB 61 3e-10 1OZS-A nrPDB 61 3e-10 3FWC-A nrPDB 61 4e-10 2I08-A nrPDB 60 8e-10 2RO8-A nrPDB 59 1e-09 2LVK-A nrPDB 59 1e-09 2K2A-A nrPDB 59 1e-09 2BL0-B nrPDB 59 1e-09 1F55-A nrPDB 59 2e-09 5JOJ-A nrPDB 59 2e-09 4Q57-A nrPDB 59 2e-09 5JOL-A nrPDB 59 2e-09 2M97-A nrPDB 58 2e-09 4P5W-A nrPDB 58 3e-09 1GJY-A nrPDB 58 3e-09 2KSZ-A nrPDB 57 4e-09 1YX7-A nrPDB 57 4e-09 1Y1X-A nrPDB 57 6e-09 4P5X-A nrPDB 57 8e-09 5Z1Q-A nrPDB 56 1e-08 1ZMZ-A nrPDB 56 1e-08 1C7W-A nrPDB 55 2e-08 1TNP-A nrPDB 55 2e-08 2G9B-A nrPDB 55 3e-08 1TRF-A nrPDB 54 3e-08 1M39-A nrPDB 54 4e-08 3MSE-B nrPDB 54 5e-08 2OPO-A nrPDB 54 5e-08 5ZGM-A nrPDB 54 5e-08 1W7I-B nrPDB 53 6e-08 1GGW-A nrPDB 53 6e-08 2M8U-A nrPDB 53 6e-08 1F4Q-A nrPDB 53 7e-08 2JOJ-A nrPDB 53 7e-08 1H4B-A nrPDB 53 1e-07 2Q4U-A nrPDB 53 1e-07 5XND-A nrPDB 52 2e-07 5PAL-A nrPDB 52 2e-07 1JF0-A nrPDB 52 2e-07 2HPS-A nrPDB 52 2e-07 2KYF-A nrPDB 51 3e-07 3JAX-C nrPDB 51 4e-07 1OQP-A nrPDB 50 5e-07 3KPX-A nrPDB 49 1e-06 3AKA-A nrPDB 49 1e-06 1SR6-C nrPDB 49 1e-06 1QXP-A nrPDB 49 2e-06 3J04-B nrPDB 49 2e-06 1SL8-A nrPDB 49 2e-06 1S36-A nrPDB 49 2e-06 2K7B-A nrPDB 48 2e-06 6IIE-A nrPDB 48 2e-06 2NCO-A nrPDB 48 2e-06 6FSA-D nrPDB 48 2e-06 4NQG-A nrPDB 48 2e-06 2LVV-A nrPDB 48 3e-06 4OKH-A nrPDB 48 3e-06 1UHK-A nrPDB 48 3e-06 5B7X-A nrPDB 47 4e-06 2K2I-A nrPDB 47 4e-06 5VE9-A nrPDB 47 4e-06 5ZH6-A nrPDB 47 6e-06 5TBY-C nrPDB 47 6e-06 5H53-C nrPDB 47 8e-06 3TZ1-A nrPDB 47 8e-06 1QX2-A nrPDB 46 1e-05 1N2D-A nrPDB 46 1e-05 1KFU-L nrPDB 46 1e-05 2N8Y-A nrPDB 46 1e-05 3CS1-A nrPDB 46 1e-05 2NLN-A nrPDB 45 2e-05 3DF0-A nrPDB 45 2e-05 1KFX-S nrPDB 45 2e-05 5I2L-A nrPDB 45 2e-05 2KQY-A nrPDB 45 2e-05 1S6J-A nrPDB 45 2e-05 1A75-A nrPDB 45 3e-05 5VT9-A nrPDB 44 4e-05 1TTX-A nrPDB 44 4e-05 6MI5-X nrPDB 44 4e-05 5CPV-A nrPDB 44 5e-05 3LCP-C nrPDB 44 5e-05 4PAL-A nrPDB 44 6e-05 2MA2-A nrPDB 44 6e-05 1RTP-1 nrPDB 43 6e-05 3PAT-A nrPDB 43 6e-05 2VRG-A nrPDB 43 6e-05 4L9M-A nrPDB 43 7e-05 1TIZ-A nrPDB 43 7e-05 1NYA-A nrPDB 43 7e-05 3A4U-B nrPDB 43 7e-05 4OCI-A nrPDB 43 7e-05 1IJ5-A nrPDB 43 7e-05 6EAZ-A nrPDB 43 8e-05 3BOW-B nrPDB 43 8e-05 4D1E-A nrPDB 43 8e-05 2SAS-A nrPDB 43 1e-04 6AGH-A nrPDB 43 1e-04 4YGB-B nrPDB 43 1e-04 1BU3-A nrPDB 43 1e-04 2W4G-C nrPDB 43 1e-04 3SIA-A nrPDB 43 1e-04 1RK9-A nrPDB 43 1e-04 1I84-U nrPDB 43 1e-04 1O1A-B nrPDB 42 1e-04 1NP8-A nrPDB 42 2e-04 1G33-A nrPDB 41 3e-04 2PMY-A nrPDB 41 3e-04 2LUC-A nrPDB 41 3e-04 2MBX-A nrPDB 41 4e-04 6AGI-A nrPDB 41 4e-04 3JBH-C nrPDB 41 5e-04 4I5K-A nrPDB 41 5e-04 3I5H-B nrPDB 41 5e-04 2I18-A nrPDB 41 5e-04 3I5I-C nrPDB 40 8e-04 1SJJ-A nrPDB 40 8e-04 3A8R-A nrPDB 40 9e-04 5H53-B nrPDB 40 0.001 6DS2-B nrPDB 40 0.001 2M1U-A nrPDB 39 0.001 1NSH-A nrPDB 39 0.001 1BOD-A nrPDB 39 0.001 1QLS-A nrPDB 39 0.002 1CB1-A nrPDB 39 0.002 3H4S-E nrPDB 39 0.002 1ZFS-A nrPDB 39 0.002 2KGR-A nrPDB 38 0.003 2FCE-A nrPDB 38 0.003 2WCE-A nrPDB 38 0.003 5TBY-E nrPDB 38 0.004 4MSP-A nrPDB 38 0.004 1Q80-A nrPDB 37 0.005 4I5L-B nrPDB 37 0.005 2OS8-B nrPDB 37 0.007 4MEW-A nrPDB 37 0.007 3TS5-B nrPDB 37 0.008 2L50-A nrPDB 36 0.011 2L0P-A nrPDB 36 0.012 3DTP-E nrPDB 36 0.012 2MJW-B nrPDB 36 0.013 4AOM-A nrPDB 35 0.018 5W1A-B nrPDB 35 0.019 4NSC-A nrPDB 35 0.026 6D1W-A nrPDB 35 0.033 5MKE-A nrPDB 35 0.033 1KQV-A nrPDB 35 0.035 5CSF-A nrPDB 34 0.036 2KHN-A nrPDB 34 0.038 5HYD-A nrPDB 34 0.041 2JXC-A nrPDB 34 0.044 2VTG-A nrPDB 34 0.044 2EC6-B nrPDB 34 0.049 2Y5I-A nrPDB 34 0.054 1DJX-A nrPDB 33 0.070 1B7T-Y nrPDB 33 0.082 1C07-A nrPDB 33 0.10 2MHH-A nrPDB 33 0.10 2AUC-A nrPDB 33 0.10 6DU8-A nrPDB 33 0.11 1WY9-A nrPDB 33 0.12 5HLO-A nrPDB 33 0.13 1DFK-Y nrPDB 32 0.14 1FI6-A nrPDB 32 0.17 4HRG-A nrPDB 32 0.25 3V4P-A nrPDB 32 0.26 4GFT-A nrPDB 32 0.26 1NUB-A nrPDB 32 0.27 5X2E-A nrPDB 32 0.27 4FTG-A nrPDB 31 0.33 2JQ6-A nrPDB 31 0.35 2KFH-A nrPDB 31 0.36 6QAA-A nrPDB 31 0.38 5LXV-B nrPDB 31 0.38 6EMI-A nrPDB 31 0.43 1SNL-A nrPDB 31 0.48 2M7L-A nrPDB 31 0.49 5FOJ-B nrPDB 30 0.53 2QPT-A nrPDB 30 0.73 2JMM-A nrPDB 30 0.82 5MV8-A nrPDB 30 0.82 3POK-A nrPDB 30 0.86 5MVF-A nrPDB 30 1.0 3QR0-A nrPDB 30 1.1 1SRA-A nrPDB 30 1.1 5KU1-A nrPDB 29 1.1 2KAY-A nrPDB 29 1.1 2Y3N-B nrPDB 29 1.2 1XX7-A nrPDB 29 1.2 5NRM-B nrPDB 29 1.3 4PCW-A nrPDB 29 1.3 4C0K-A nrPDB 29 1.3 4YBH-B nrPDB 29 1.4 5VP3-A nrPDB 29 1.8 5LPU-C nrPDB 29 1.9 3NSO-A nrPDB 29 1.9 1IQ3-A nrPDB 28 1.9 6R5K-D nrPDB 28 2.1 3QR1-A nrPDB 28 2.5 5LJ6-A nrPDB 28 2.5 4DUQ-A nrPDB 28 2.6 4CFQ-A nrPDB 28 2.7 4V6W-Az nrPDB 28 2.8 4MN0-A nrPDB 28 3.3 2KLD-A nrPDB 28 3.3 5NRK-B nrPDB 28 3.6 1QJT-A nrPDB 28 3.7 3TO3-A nrPDB 28 4.3 5CUU-A nrPDB 27 4.3 2FNA-A nrPDB 27 4.9 2JTT-A nrPDB 27 5.0 1E6V-C nrPDB 27 5.5 2G2B-A nrPDB 27 5.6 5CUY-A nrPDB 27 6.5 2DTU-A nrPDB 27 6.5 2KQ6-A nrPDB 27 7.0 2QXL-A nrPDB 27 8.5 2CXJ-A nrPDB 27 9.0 >2GGZ-A nrPDB Length = 211 Score = 273 bits (697), Expect = 5e-74, Method: Composition-based stats. Identities = 209/209 (100%), Positives = 209/209 (100%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV 60 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV Sbjct: 3 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV 62 Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 120 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV Sbjct: 63 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 122 Query: 121 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR 180 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR Sbjct: 123 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR 182 Query: 181 VICNGKQPDMETDSSKSPDKAGLGKVKMK 209 VICNGKQPDMETDSSKSPDKAGLGKVKMK Sbjct: 183 VICNGKQPDMETDSSKSPDKAGLGKVKMK 211 >2NA0-A nrPDB Length = 205 Score = 213 bits (542), Expect = 5e-56, Method: Composition-based stats. Identities = 93/201 (46%), Positives = 144/201 (71%), Gaps = 7/201 (3%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 +GKS+ + + + E H WY+ FM E PSG TL+EF+ GL+ L+ A+++++Q++ Sbjct: 6 DGKSV----EELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFE 61 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 TFD NKDG++DF+E+ AA++L+++ K+EQKL+WYFKLYD DGNG ID++ELL + A++A Sbjct: 62 TFDFNKDGYIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRA 121 Query: 123 LN--GQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLR 180 +N T++ EEF + VF KID+N DGEL+LEEF+ G+ KDQ LL+ + +S D + ++R Sbjct: 122 INPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVR 181 Query: 181 VICNGKQPDMETDSSKSPDKA 201 + NG+Q D E S + + A Sbjct: 182 RLQNGEQ-DEEGASGRETEAA 201 >2R2I-A nrPDB Length = 198 Score = 201 bits (512), Expect = 1e-52, Method: Composition-based stats. Identities = 90/179 (50%), Positives = 137/179 (76%), Gaps = 2/179 (1%) Query: 12 KAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF 71 + + E H WY+ FM E PSG TL+EFK GL+ L+ ANK+++Q++ TFD NKDG+ Sbjct: 9 EELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDGY 68 Query: 72 VDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN-GQQTLS 130 +DF+E++AA++L+++ K++QKL+WYFKLYD DGNG ID+ ELL++ A++A+N + ++ Sbjct: 69 IDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMT 128 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICN-GKQP 188 EEF N+VF KIDIN DGEL+LEEF+ G+ KD+ LL+I+ +S D ++++++I N GK P Sbjct: 129 AEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILTRSLDLTHIVKLIQNDGKNP 187 >5T7C-A nrPDB Length = 193 Score = 189 bits (481), Expect = 5e-49, Method: Composition-based stats. Identities = 60/166 (36%), Positives = 97/166 (58%), Gaps = 6/166 (3%) Query: 10 DQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 + E WY+ F+ + P+G T+ EFK + A+K + V+ TFDTN D Sbjct: 18 ENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGD 77 Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL------ 123 G +DF EFI A+++ + K+EQKLKW F +YD DGNG I ++E+L++ A+ + Sbjct: 78 GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMK 137 Query: 124 NGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 + +PE+ + +F ++D NNDG+L+LEEFI G D ++ ++ Sbjct: 138 MPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183 >1BJF-A nrPDB Length = 193 Score = 188 bits (478), Expect = 1e-48, Method: Composition-based stats. Identities = 60/167 (35%), Positives = 94/167 (56%), Gaps = 6/167 (3%) Query: 9 GDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 + E WY+ F+ + PSG ++ EFK + G A+K + V+ TFD N Sbjct: 17 LESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANG 76 Query: 69 DGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL----- 123 DG +DF EFI A+++ + K+EQKLKW F +YD DGNG I K E+L++ A+ + Sbjct: 77 DGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVM 136 Query: 124 -NGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 + +PE+ +F ++D N DG+L+LEEFI G D ++ ++ Sbjct: 137 KMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183 >5M6C-E nrPDB Length = 193 Score = 180 bits (457), Expect = 4e-46, Method: Composition-based stats. Identities = 56/176 (31%), Positives = 95/176 (53%), Gaps = 6/176 (3%) Query: 10 DQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 + E WY+ F+ + P+G+ + EFK + A+K + V+ FDTN D Sbjct: 18 ENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSD 77 Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL------ 123 G +DF EFI A+++ + ++EQKL W F +YD DGNG I + E+L++ A+ + Sbjct: 78 GTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMK 137 Query: 124 NGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVL 179 + +PE+ +F ++D NNDG+L+LEEFI G D ++ ++ ++ Sbjct: 138 MPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSTSQF 193 >2L2E-A nrPDB Length = 190 Score = 180 bits (456), Expect = 4e-46, Method: Composition-based stats. Identities = 52/166 (31%), Positives = 88/166 (53%), Gaps = 6/166 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 +E WY+ F + PSG EF+ + + + V+N FD +K+G Sbjct: 19 STRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNG 78 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG----- 125 ++DF EFI A+++ + ++ KL W F+LYD D NG I +E+L + A+ + G Sbjct: 79 YIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKL 138 Query: 126 -QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVY 170 + +PE+ +N +F+ +D N DG+LTLEEF G +D ++ + Sbjct: 139 PEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184 >2JUL-A nrPDB Length = 256 Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats. Identities = 46/162 (28%), Positives = 84/162 (51%), Gaps = 6/162 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q +E YR F E P+GL FK + A + ++N FD + +G Sbjct: 85 QTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL- 129 + F +F+ ++++++ + +KLKW F LYD + +G I K E+L + ++ + G+ T Sbjct: 145 AIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 Query: 130 -----SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +P E + F K+D N DG +T++EF+ KD++++ Sbjct: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 >2LCP-A nrPDB Length = 190 Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats. Identities = 53/166 (31%), Positives = 91/166 (54%), Gaps = 6/166 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 + +E WY+ F+ + PSG F+ + K V+N FD NKDG Sbjct: 19 KTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDG 78 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG----- 125 ++F EFI A+++ + +++KL+W FKLYD D +G I +NE+LD+ A+ + G Sbjct: 79 RIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVEL 138 Query: 126 -QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVY 170 ++ +PE+ ++ +F +D N DG+LTL+EF G D +++ + Sbjct: 139 PEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALS 184 >2JU0-A nrPDB Length = 190 Score = 170 bits (432), Expect = 3e-43, Method: Composition-based stats. Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 6/165 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 +E W++ F+ + PSG +F + + ++ FD + +G Sbjct: 19 STYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNG 78 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG----- 125 F+ F EFI ++ + +E+KL W F+LYD + +G I +E+L + +V + G Sbjct: 79 FIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTL 138 Query: 126 -QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 + +PE + +F +D N DG +TL+EF G D ++ + Sbjct: 139 NEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGAL 183 >3DD4-A nrPDB Length = 229 Score = 170 bits (431), Expect = 3e-43, Method: Composition-based stats. Identities = 49/163 (30%), Positives = 87/163 (53%), Gaps = 6/163 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q +E + YR F E PSG+ FK + + + ++N FDT+ +G Sbjct: 58 QSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNG 117 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL- 129 V F +FI ++++++ +++KL W F LYD + +G I K E+LD+ A+ + G+ T Sbjct: 118 AVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYP 177 Query: 130 -----SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLE 167 +P + + F K+D N DG +T++EFI KD++++ Sbjct: 178 VLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMR 220 >6EPA-A nrPDB Length = 187 Score = 170 bits (431), Expect = 4e-43, Method: Composition-based stats. Identities = 48/162 (29%), Positives = 88/162 (54%), Gaps = 5/162 (3%) Query: 14 VPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD 73 +E W++ F+ + P+GL T F + + +K V+ FD N DG ++ Sbjct: 22 FTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIE 81 Query: 74 FLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ-----T 128 F EFI A+++ + +++KL W F+LYD D +G I + E+ ++ A+ + GQQ Sbjct: 82 FEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDE 141 Query: 129 LSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVY 170 +P++ ++ +F ++D N+D LTLEEF G D +++ + Sbjct: 142 NTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 183 >1S6C-A nrPDB Length = 183 Score = 169 bits (429), Expect = 7e-43, Method: Composition-based stats. Identities = 49/165 (29%), Positives = 92/165 (55%), Gaps = 6/165 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q +E V YR F E PSG+ FK + + A+ + ++N FDT + G Sbjct: 12 QTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTG 71 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL- 129 V F +F+ A++++++ + +KL+W F LYD + +G I+K E++D+ A+ + G+ T Sbjct: 72 SVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYP 131 Query: 130 -----SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 +P + +++ F K+D N DG +TL+EF+ +D +++ + Sbjct: 132 VLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSL 176 >1S1E-A nrPDB Length = 224 Score = 168 bits (425), Expect = 2e-42, Method: Composition-based stats. Identities = 49/165 (29%), Positives = 92/165 (55%), Gaps = 6/165 (3%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q +E V YR F E PSG+ FK + + A+ + ++N FDT + G Sbjct: 45 QTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTG 104 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL- 129 V F +F+ A++++++ + +KL+W F LYD + +G I+K E++D+ A+ + G+ T Sbjct: 105 SVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYP 164 Query: 130 -----SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 +P + +++ F K+D N DG +TL+EF+ +D +++ + Sbjct: 165 VLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSL 209 >2I94-A nrPDB Length = 202 Score = 165 bits (418), Expect = 1e-41, Method: Composition-based stats. Identities = 57/186 (30%), Positives = 95/186 (51%), Gaps = 17/186 (9%) Query: 1 MGNGKSIAGDQK---------AVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQ 51 MGN KS A ++ +E WY++F+ E PSG T EF+T+ Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + V+ +FD N DG +DF E++ A+++ K QKL+W F LYD DGNG+I KN Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 112 ELLDMFMAVQALNGQQTL--------SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 E+L++ A+ + + +PE+ ++ +D +LT +EFI G ++ Sbjct: 121 EVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANK 180 Query: 164 DLLEIV 169 ++L ++ Sbjct: 181 EILRLI 186 >1JBA-A nrPDB Length = 204 Score = 164 bits (415), Expect = 3e-41, Method: Composition-based stats. Identities = 64/178 (35%), Positives = 106/178 (59%), Gaps = 17/178 (9%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 NG A D + WY+ F+ E PSG +HEFK + N++A ++++ ++ Sbjct: 13 NGAVGAAD-----AAQLQEWYKKFLEECPSGTLFMHEFKRFFKVPD-NEEATQYVEAMFR 66 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 FDTN D +DFLE++AA+NL+++ +E KLKW FK+YD D NG ID+ ELLD+ ++ Sbjct: 67 AFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYK 126 Query: 123 L-----------NGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 L + L+PEE ++ +F +D N DG+L+L EF+ G +D+ +++++ Sbjct: 127 LKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKML 184 >2D8N-A nrPDB Length = 207 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 49/166 (29%), Positives = 92/166 (55%), Gaps = 8/166 (4%) Query: 12 KAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF 71 +E WY++F+ + P+G T +F+++ + + V+ +FD+N DG Sbjct: 28 TKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGT 87 Query: 72 VDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL-- 129 +DF E++ A+++ K QKL+W F LYD DGNG+I KNE+L++ MA+ + + + Sbjct: 88 LDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKL 147 Query: 130 ------SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 +PE+ ++ N+D +LT +EFI G ++++L ++ Sbjct: 148 LPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLI 193 >4IL1-A nrPDB Length = 823 Score = 150 bits (378), Expect = 5e-37, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 12 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 69 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 123 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + + DI+ DG++ EEF+ M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMMTA 148 Score = 123 bits (308), Expect = 7e-29, Method: Composition-based stats. Identities = 41/149 (27%), Positives = 68/149 (45%), Gaps = 9/149 (6%) Query: 14 VPTQETHVWYRTFMMEY--PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF 71 E + F SG ++ EF +L LQ N + +V + FDT+ +G Sbjct: 172 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ-----QNPLVQRVIDIFDTDGNGE 226 Query: 72 VDFLEFIAAVNLIM-QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 VDF EFI V+ + EQKL++ F++YD D +G I EL + + N + Sbjct: 227 VDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNN-LKDTQ 285 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGM 159 ++ ++ D + DG ++ EEF + Sbjct: 286 LQQIVDKTIINADKDGDGRISFEEFCAVV 314 Score = 88.9 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 68/157 (43%), Gaps = 18/157 (11%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 +G EF T++ + + + + I + + FD + +G++ E + + ++ + Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 119 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE----------------EF 134 +++ + D DG+G ++ E + M A G E + Sbjct: 120 EEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKR 179 Query: 135 INLVFHKIDINNDGELTLEEFING--MAKDQDLLEIV 169 + F K+D++N G L++EEF++ + ++ + ++ Sbjct: 180 LGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVI 216 Score = 87.0 bits (214), Expect = 5e-18, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 66/189 (34%), Gaps = 40/189 (21%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G + E + ++ G ++ +D++ D + DG V++ Sbjct: 82 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 139 Query: 75 LEFIAAVNLIM----------------------QEKMEQKLKWYFKLYDADGNGSIDKNE 112 EF+ + ++L FK D D +GS+ E Sbjct: 140 EEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEE 199 Query: 113 LLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK------DQDLL 166 L + V D + +GE+ +EFI G+++ + L Sbjct: 200 F----------MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKL 249 Query: 167 EIVYKSFDF 175 ++ +D Sbjct: 250 RFAFRIYDM 258 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 54 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 55 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 94 >4OY4-A nrPDB Length = 415 Score = 148 bits (374), Expect = 1e-36, Method: Composition-based stats. Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 9/166 (5%) Query: 7 IAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDT 66 + E + F + G T E T++ G N + D + N D Sbjct: 8 GSDQLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDA 65 Query: 67 NKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 + DG +DF EF+ + M++ E++++ F+++D DGNG I EL + + Sbjct: 66 DGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL----- 120 Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYK 171 + L+ EE ++ + + DI+ DG++ EEF+ M + ++ + Sbjct: 121 GEKLTDEE-VDEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYVR 165 >3U0K-A nrPDB Length = 442 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + DG +DF EF Sbjct: 305 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGDGTIDFPEF 362 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 363 LIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 416 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + + DI+ DG++ EEF+ M Sbjct: 417 EMIREADIDGDGQVNYEEFVQMMTA 441 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 44/100 (44%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 294 TRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 347 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + DG + EF+ MA+ ++ + ++ FD Sbjct: 348 EVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFD 387 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G + E + ++ G ++ +D++ D + DG V++ Sbjct: 375 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 432 Query: 75 LEFIAAVNLI 84 EF+ + Sbjct: 433 EEFVQMMTAK 442 >3EK4-A nrPDB Length = 451 Score = 146 bits (368), Expect = 7e-36, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 314 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 371 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 372 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 425 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + + DI+ DG++ EEF+ M Sbjct: 426 EMIREADIDGDGQVNYEEFVQMMTA 450 Score = 76.2 bits (186), Expect = 9e-15, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 60/167 (35%), Gaps = 24/167 (14%) Query: 23 YRTFMMEYPSGLQTLHE-FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 + F P G F G + D + N + +DF E + Sbjct: 239 HDFFKSAMPEGYIQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKG---IDFKEDGNIL 295 Query: 82 NLIMQEKMEQKL--------KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 ++ +L K F L+D DG+G+I EL + ++ + L Sbjct: 296 GHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-- 353 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 + +++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 354 ----MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 396 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G + E + ++ G ++ +D++ D + DG V++ Sbjct: 384 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 441 Query: 75 LEFIAAVNLI 84 EF+ + Sbjct: 442 EEFVQMMTAK 451 >5UKG-A nrPDB Length = 419 Score = 142 bits (359), Expect = 9e-35, Method: Composition-based stats. Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + DG DF EF Sbjct: 282 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGDGTFDFPEF 339 Query: 78 IAAVNLIMQEKM-EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M ++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 340 LTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDL-----GEKLTDEE-VD 393 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + DI+ DG++ EEF+ M Sbjct: 394 EMIRVADIDGDGQVNYEEFVQMMTA 418 Score = 70.1 bits (170), Expect = 7e-13, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 43/96 (44%), Gaps = 12/96 (12%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F L+D DG+G+I EL + ++ + L + +++D Sbjct: 275 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDA 328 Query: 145 NNDGELTLEEFINGMAKD------QDLLEIVYKSFD 174 + DG EF+ MA+ ++ + ++ FD Sbjct: 329 DGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFD 364 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 14 VPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD 73 V +E +R F + +G E + ++ G ++ +D++ D + DG V+ Sbjct: 351 VTEEEIREAFRVFDKD-GNGYIGAAELRHVMTDLGEKLT-DEEVDEMIRVADIDGDGQVN 408 Query: 74 FLEFIAAVNLI 84 + EF+ + Sbjct: 409 YEEFVQMMTAK 419 >4I2Y-A nrPDB Length = 421 Score = 138 bits (347), Expect = 2e-33, Method: Composition-based stats. Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + DG DF EF Sbjct: 284 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGDGTFDFPEF 341 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M + E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 342 LTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDL-----GEKLTDEE-VD 395 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + DI+ DG++ EEF+ M Sbjct: 396 EMIRVADIDGDGQVNYEEFVQMMTA 420 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 44/102 (43%), Gaps = 12/102 (11%) Query: 79 AAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV 138 A + E+ + K F L+D DG+G+I EL + ++ + L + Sbjct: 271 EATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------M 324 Query: 139 FHKIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 +++D + DG EF+ MA+ ++ + ++ FD Sbjct: 325 INEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFD 366 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 30/70 (42%), Gaps = 2/70 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G E + ++ G ++ +D++ D + DG V++ Sbjct: 354 SEEEIREAFRVFDKD-GNGYIGAAELRHVMTDLGEKLT-DEEVDEMIRVADIDGDGQVNY 411 Query: 75 LEFIAAVNLI 84 EF+ + Sbjct: 412 EEFVQMMTAK 421 >3WFN-B nrPDB Length = 182 Score = 132 bits (333), Expect = 9e-32, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 18 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 75 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 76 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 129 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + + DI+ DG++ EEF+ M Sbjct: 130 EMIREADIDGDGQVNYEEFVQMMTA 154 Score = 70.4 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 45/97 (46%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 +G EF T++ + + + + I + + FD + +G++ E + + ++ + Sbjct: 66 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 125 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 +++ + D DG+G ++ E + M A G++ Sbjct: 126 EEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEE 162 Score = 63.1 bits (152), Expect = 7e-11, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 7 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 60 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 61 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 100 >2N6A-A nrPDB Length = 173 Score = 131 bits (330), Expect = 2e-31, Method: Composition-based stats. Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 9/144 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 13 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 70 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 71 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 124 Query: 137 LVFHKIDINNDGELTLEEFINGMA 160 + + DI+ DG++ EEF+ M Sbjct: 125 EMIREADIDGDGQVNYEEFVQMMT 148 Score = 60.8 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 43/95 (45%), Gaps = 12/95 (12%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 E+ + K F L+D DG+G+I EL + ++ + L + +++D + Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDAD 60 Query: 146 NDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 +G + EF+ MA+ ++ + ++ FD Sbjct: 61 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 95 >6O20-F nrPDB Length = 169 Score = 130 bits (327), Expect = 5e-31, Method: Composition-based stats. Identities = 40/159 (25%), Positives = 73/159 (45%), Gaps = 9/159 (5%) Query: 4 GKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNT 63 G +A E + F + G T E T++ G N + D + N Sbjct: 18 GSHMADQLTEEQIAEFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINE 75 Query: 64 FDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 D + +G +DF EF+ + M++ E++++ F+++D DGNG I EL + + Sbjct: 76 VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-- 133 Query: 123 LNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + L+ EE ++ + + DI+ DG++ EEF+ M Sbjct: 134 ---GEKLTDEE-VDEMIREADIDGDGQVNYEEFVQMMTA 168 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 21 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 74 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 75 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 114 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G + E + ++ G ++ +D++ D + DG V++ Sbjct: 102 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 159 Query: 75 LEFIAAVNLI 84 EF+ + Sbjct: 160 EEFVQMMTAK 169 >2F2P-A nrPDB Length = 179 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 9/166 (5%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 12 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 69 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 123 Query: 137 LVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVI 182 + + DI+ DG++ EEF+ M + N +R I Sbjct: 124 EMIREADIDGDGQVNYEEFVQMMTAKGGGGGAAARKEVIRNKIRAI 169 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 54 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 55 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 94 >4E53-A nrPDB Length = 185 Score = 126 bits (316), Expect = 8e-30, Method: Composition-based stats. Identities = 38/143 (26%), Positives = 70/143 (48%), Gaps = 9/143 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 19 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 76 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + + L+ EE ++ Sbjct: 77 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VD 130 Query: 137 LVFHKIDINNDGELTLEEFINGM 159 + + DI+ DG++ EEF+ M Sbjct: 131 EMIREADIDGDGQVNYEEFVQMM 153 Score = 60.4 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 8 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 61 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 62 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 101 >6HCS-A nrPDB Length = 167 Score = 125 bits (315), Expect = 9e-30, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 9/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 12 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 69 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + M++ E++++ F+++D DGNG I EL + + L+ EE ++ Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNL-----GEKLTDEE-VD 123 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + + DI+ DG++ EEF+ M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMMTA 148 Score = 66.2 bits (160), Expect = 9e-12, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 45/99 (45%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 +G EF T++ + + + + I + + FD + +G++ E + + ++ + Sbjct: 60 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTD 119 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 +++ + D DG+G ++ E + M A G + L Sbjct: 120 EEVDEMIREADIDGDGQVNYEEFVQMMTAKLEGTGLEVL 158 Score = 60.4 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + E+ + K F L+D DG+G+I EL + ++ + L + + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MIN 54 Query: 141 KIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 55 EVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 94 >5I0I-E nrPDB Length = 145 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 37/152 (24%), Positives = 73/152 (48%), Gaps = 10/152 (6%) Query: 12 KAVPTQETHVWYRTFMM--EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 + ++ + F + + G T E T++ G N + D + N D + + Sbjct: 1 DQLTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGN 59 Query: 70 GFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT 128 G +DF EF+ + M++ E++++ F+++D DGNG I EL + + + Sbjct: 60 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEK 114 Query: 129 LSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 L+ EE ++ + + DI+ DG++ EEF+ M Sbjct: 115 LTDEE-VDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 43/96 (44%), Gaps = 12/96 (12%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F L D DG+G+I EL + ++ + L + +++D Sbjct: 3 LTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDA 56 Query: 145 NNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 + +G + EF+ MA+ ++ + ++ FD Sbjct: 57 DGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 92 >2ZFD-A nrPDB Length = 226 Score = 120 bits (302), Expect = 3e-28, Method: Composition-based stats. Identities = 47/188 (25%), Positives = 87/188 (46%), Gaps = 12/188 (6%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMMEY----PSGLQTLHEFKTLLGLQGLNQKANKH 56 +G+ + +A D E Y F GL EF+ L L N+K + Sbjct: 30 LGDPELLARD-TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLF 86 Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ-EKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D+V++ FDT +G + F EF A+++ ++ K+ + F+LYD G I++ E+ Sbjct: 87 ADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 Query: 116 MFMAVQALNG--QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSF 173 M +A A +G + E+ I+ F + D +DG++ EE+ + + + LL+ + + Sbjct: 147 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQY 206 Query: 174 --DFSNVL 179 D + Sbjct: 207 LKDITTTF 214 >1CLM-A nrPDB Length = 148 Score = 120 bits (301), Expect = 4e-28, Method: Composition-based stats. Identities = 41/153 (26%), Positives = 72/153 (47%), Gaps = 9/153 (5%) Query: 8 AGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN 67 A + E + F + G T E T++ G N + D + N D + Sbjct: 1 AQELTEEQIAEFKEAFALFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDAD 58 Query: 68 KDGFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ 126 +G +DF EF++ + M+E+ E++L FK++D DGNG I EL + + Sbjct: 59 GNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-----G 113 Query: 127 QTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 + L+ +E ++ + + DI+ DG + EEF+ M Sbjct: 114 EKLTDDE-VDEMIREADIDGDGHINYEEFVRMM 145 Score = 56.2 bits (134), Expect = 9e-09, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F L+D DG+G+I EL + ++ + L + +++D Sbjct: 4 LTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDA 57 Query: 145 NNDGELTLEEFINGMAK 161 + +G + EF++ MA+ Sbjct: 58 DGNGTIDFPEFLSLMAR 74 >5A2H-A nrPDB Length = 149 Score = 120 bits (300), Expect = 6e-28, Method: Composition-based stats. Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 9/146 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 E + F + G T E T++ G N + D + N D + +G +DF Sbjct: 9 QISEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDF 66 Query: 75 LEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 EF+ + M++ E++LK F+++D D NG I EL + + + L+ EE Sbjct: 67 PEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-----GEKLTDEE 121 Query: 134 FINLVFHKIDINNDGELTLEEFINGM 159 ++ + + D++ DG++ EEF+ M Sbjct: 122 -VDEMIREADVDGDGQINYEEFVKVM 146 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 43/105 (40%), Gaps = 6/105 (5%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + + + + K F L+D DG+G I EL + ++ + L + + Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQD------MIN 54 Query: 141 KIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNG 185 ++D + +G + EF+N MA+ + + + V NG Sbjct: 55 EVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNG 99 >1GGZ-A nrPDB Length = 148 Score = 117 bits (293), Expect = 4e-27, Method: Composition-based stats. Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 9/146 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 E + F + G T E T++ G N + + + D + +G VDF Sbjct: 8 QVTEFKEAFSLFDKD-GDGCITTRELGTVMRSLGQNPT-EAELRDMMSEIDRDGNGTVDF 65 Query: 75 LEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 EF+ + M++ E++++ F+++D DGNG + EL + + + LS EE Sbjct: 66 PEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRL-----GEKLSDEE 120 Query: 134 FINLVFHKIDINNDGELTLEEFINGM 159 ++ + D + DG++ EEF+ + Sbjct: 121 -VDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 41/89 (46%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 +G EF ++ + + + I + + FD + +GFV E + + ++ + Sbjct: 59 GNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSD 118 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMA 119 +++ + D DG+G ++ E + + ++ Sbjct: 119 EEVDEMIRAADTDGDGQVNYEEFVRVLVS 147 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 43/99 (43%), Gaps = 12/99 (12%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + E+ + K F L+D DG+G I EL + ++ + L + + Sbjct: 1 ADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRD------MMSE 54 Query: 142 IDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 ID + +G + EF+ MA+ +++ + ++ FD Sbjct: 55 IDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFD 93 >1UHN-A nrPDB Length = 189 Score = 117 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 11/177 (6%) Query: 12 KAVPTQETHVWYRTFMMEY----PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN 67 E Y F GL EF+ L L N+K + D+V++ FDT Sbjct: 9 TVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVFDLFDTK 66 Query: 68 KDGFVDFLEFIAAVNLIMQ-EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG- 125 +G + F EF A+++ ++ K+ + F+LYD G I++ E+ M +A A +G Sbjct: 67 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 126 Query: 126 -QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSF--DFSNVL 179 + E+ I+ F + D +DG++ EE+ + + + LL+ + + D + Sbjct: 127 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTLQYLKDITTTF 183 >1V1G-A nrPDB Length = 222 Score = 116 bits (290), Expect = 8e-27, Method: Composition-based stats. Identities = 39/169 (23%), Positives = 79/169 (46%), Gaps = 9/169 (5%) Query: 9 GDQKAVPTQETHVWYRTFMMEYPS----GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 +E Y F S GL EF+ L L + N D++++ F Sbjct: 26 ASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQ--LALFRNRNRRNLFADRIFDVF 83 Query: 65 DTNKDGFVDFLEFIAAVNLIMQ-EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL 123 D ++G ++F EF+ ++ + + +K+K+ FKLYD G I++ EL +M +A+ Sbjct: 84 DVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMVVALLHE 143 Query: 124 NGQQTLSP--EEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVY 170 + E ++ F + D NDG++ ++E+ + ++ + L++ + Sbjct: 144 SELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKNMT 192 >3HZT-A nrPDB Length = 467 Score = 113 bits (284), Expect = 4e-26, Method: Composition-based stats. Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 20/167 (11%) Query: 11 QKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGL----------NQKANKHID 58 K +ET + F + G E + + +D Sbjct: 305 SKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 364 Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + + D +++G++++ EF+ ++L F+ +D+DG+G I EL +F Sbjct: 365 HILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG 424 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDL 165 T +E + V + D NNDGE+ EEF+ M K D+ Sbjct: 425 V--------TEVDDETWHQVLQECDKNNDGEVDFEEFVEMMQKICDV 463 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 40/90 (44%), Gaps = 5/90 (5%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ-----QTLSPEEFIN 136 + + + ++L F+ D +G+G +D+ EL++ + + G + E ++ Sbjct: 305 SKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 364 Query: 137 LVFHKIDINNDGELTLEEFINGMAKDQDLL 166 + +D + +G + EF+ Q LL Sbjct: 365 HILQSVDFDRNGYIEYSEFVTVCMDKQLLL 394 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q + + ++ F + SG T E L G+ + ++ QV D N DG Sbjct: 391 QLLLSRERLLAAFQQFDSD-GSGKITNEELG---RLFGVTEVDDETWHQVLQECDKNNDG 446 Query: 71 FVDFLEFIAAVNLIMQEKMEQ 91 VDF EF+ + I K++ Sbjct: 447 EVDFEEFVEMMQKICDVKVKH 467 >4ORC-B nrPDB Length = 170 Score = 113 bits (283), Expect = 6e-26, Method: Composition-based stats. Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 10/163 (6%) Query: 1 MGNGKSIAGDQ-KAVPTQETHVWYRTFMMEY--PSGLQTLHEFKTLLGLQGLNQKANKHI 57 MGN S + E + F SG ++ EF +L LQ N + Sbjct: 1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQ-----QNPLV 55 Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIM-QEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 +V + FDT+ +G VDF EFI V+ + EQKL++ F++YD D +G I EL + Sbjct: 56 QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115 Query: 117 FMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 + N + ++ ++ D + DG ++ EEF + Sbjct: 116 LKMMVGNN-LKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 16/91 (17%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++L FK D D +GS+ E L + V D + +GE+ Sbjct: 21 KRLGKRFKKLDLDNSGSLSVEEF----------MSLPELQQNPLVQRVIDIFDTDGNGEV 70 Query: 151 TLEEFINGMAK------DQDLLEIVYKSFDF 175 +EFI G+++ + L ++ +D Sbjct: 71 DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDM 101 >1DTL-A nrPDB Length = 161 Score = 110 bits (274), Expect = 6e-25, Method: Composition-based stats. Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 K+ E + F++ G + E ++ + G N + + ++ + Sbjct: 6 KAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTP-EELQEMIDEV 64 Query: 65 DTNKDGFVDFLEFIAAVNLIMQ----EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 120 D + G VDF EF+ + M+ K E++L F+++D + +G ID EL M A Sbjct: 65 DEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT 124 Query: 121 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 E+ I + D NNDG + +EF+ M Sbjct: 125 G------ETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 38/88 (43%), Gaps = 7/88 (7%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADG-NGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + A + E+ + + K F ++ +GSI EL + + Q +PEE Sbjct: 2 DDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-----GQNPTPEE 56 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + ++D + G + +EF+ M + Sbjct: 57 -LQEMIDEVDEDGSGTVDFDEFLVMMVR 83 >1DGU-A nrPDB Length = 183 Score = 109 bits (273), Expect = 8e-25, Method: Composition-based stats. Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 28/187 (14%) Query: 10 DQKAVPTQETHVWYRTFMMEYP-------SGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 D + QE + +R F P S L+ F+ +L L L KAN +++ Sbjct: 10 DLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL--KANPFKERICR 67 Query: 63 TFDT----NKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 F T + F DFL+ ++ + + K + F+++D D +G++++ +L + Sbjct: 68 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVN 125 Query: 119 AVQALNGQQTLSPEEF---INLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDF 175 + LS E I+ + + DI+ DG + L EF + ++ +S DF Sbjct: 126 CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH----------VISRSPDF 175 Query: 176 SNVLRVI 182 ++ +++ Sbjct: 176 ASSFKIV 182 >5JN2-A nrPDB Length = 525 Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 35/158 (22%), Positives = 65/158 (41%), Gaps = 19/158 (12%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEF----KTLLGLQGLNQKA------NKHIDQVYNTFD 65 T+E + G E K L+ ++G + +DQV + D Sbjct: 375 TKELTAIFHKMDKN-GDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVD 433 Query: 66 TNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 +K+G++++ EF+ ++L+ F+++D+D +G I EL +F Sbjct: 434 FDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGV------ 487 Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 + E V ++D NNDGE+ +EF + K Sbjct: 488 --SDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLC 523 Score = 53.9 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 28/173 (16%), Positives = 65/173 (37%), Gaps = 15/173 (8%) Query: 24 RTFMMEYPSGLQTL-----HEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFI 78 R + PS + HE+ + ++ + + N + + Sbjct: 304 RKMLTYVPSMRISARDALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALL 363 Query: 79 AAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ-----QTLSPEE 133 + + + ++L F D +G+G +D+ EL++ + + + GQ + E Sbjct: 364 YMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEH 423 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAKDQDL-----LEIVYKSFDFSNVLRV 181 ++ V +D + +G + EF+ + L LE ++ FD N ++ Sbjct: 424 EVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKI 476 >3K21-A nrPDB Length = 191 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 6/135 (4%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 + E G T + K L GL N D + + D++ G +D+ EFIAA + + Sbjct: 61 LDEDGKGYITKEQLKKGLEKDGLKLPYN--FDLLLDQIDSDGSGKIDYTEFIAAA--LDR 116 Query: 87 EKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 +++ +KL + F+++D D +G I EL + G T + + +D N Sbjct: 117 KQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNK-KGNITQRDVNRVKRMIRDVDKN 175 Query: 146 NDGELTLEEFINGMA 160 NDG++ EF M Sbjct: 176 NDGKIDFHEFSEMMK 190 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 +KLK F + D DG G I K +L L P F +L+ +ID + G++ Sbjct: 52 EKLKSTFLVLDEDGKGYITKEQLKK------GLEKDGLKLPYNF-DLLLDQIDSDGSGKI 104 Query: 151 TLEEFINGM----AKDQDLLEIVYKSFDFSN 177 EFI + L+ ++ FD N Sbjct: 105 DYTEFIAAALDRKQLSKKLIYCAFRVFDVDN 135 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 5/82 (6%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLL----GLQGLNQKANKHIDQVY 61 + A D+K + + + +R F ++ G T E +L + Q+ + ++ Sbjct: 111 AAALDRKQLSKKLIYCAFRVFDVD-NDGEITTAELAHILYNGNKKGNITQRDVNRVKRMI 169 Query: 62 NTFDTNKDGFVDFLEFIAAVNL 83 D N DG +DF EF + L Sbjct: 170 RDVDKNNDGKIDFHEFSEMMKL 191 >2AAO-A nrPDB Length = 166 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 11/152 (7%) Query: 12 KAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 +++ +E F + SG T E K L G N K ++ +D + D + Sbjct: 19 ESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILD-LMQAADVDNS 77 Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 G +D+ EFIAA + + + E L F +D DG+G I +EL ++ Sbjct: 78 GTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQ--------ACEEFG 129 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + I + +D +NDG + EF+ M K Sbjct: 130 VEDVRIEELMRDVDQDNDGRIDYNEFVAMMQK 161 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 34/88 (38%), Gaps = 10/88 (11%) Query: 77 FIAAVNLIMQEKMEQK----LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 F ++ E + ++ LK F + DAD +G I EL V A + + Sbjct: 9 FKKMALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILD- 67 Query: 133 EFINLVFHKIDINNDGELTLEEFINGMA 160 + D++N G + +EFI Sbjct: 68 -----LMQAADVDNSGTIDYKEFIAATL 90 >4JWQ-A nrPDB Length = 199 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 6/136 (4%) Query: 26 FMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 ++ E G T ++ K L GL N D + + D++ G +D+ EF+AA + Sbjct: 66 YLDEDGKGNITKNQLKKGLENSGLKLPQN--FDVLLDQIDSDGSGRIDYTEFLAAA--LD 121 Query: 86 QEKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 ++ + +KL + F+++D D +G I EL + G T + + ++D Sbjct: 122 RKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNK-KGSITQKDVNQVKKMIQEVDK 180 Query: 145 NNDGELTLEEFINGMA 160 NNDG++ EF M Sbjct: 181 NNDGKIDFYEFCEMMK 196 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLL----GLQGLNQKANKHIDQVY 61 + A D+K + + + +R F ++ G T E +L + QK + ++ Sbjct: 117 AAALDRKHLSKKLIYCAFRVFDVD-NDGEITTAELAHILYNGNKKGSITQKDVNQVKKMI 175 Query: 62 NTFDTNKDGFVDFLEFIAAVNLI 84 D N DG +DF EF + L Sbjct: 176 QEVDKNNDGKIDFYEFCEMMKLK 198 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 11/91 (12%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q+LK F D DG G+I KN+L L P+ F +++ +ID + G + Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKK------GLENSGLKLPQNF-DVLLDQIDSDGSGRI 110 Query: 151 TLEEFINGMAKDQDLLEIV----YKSFDFSN 177 EF+ + L + + ++ FD N Sbjct: 111 DYTEFLAAALDRKHLSKKLIYCAFRVFDVDN 141 >2L1W-A nrPDB Length = 149 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 71/143 (49%), Gaps = 9/143 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 + + F + G T+ E T++ N + D + + D + +G ++F EF Sbjct: 11 DFKEAFGLFDKD-GDGCITVEELATVIRSLDQNPTEEELQD-MISEVDADGNGTIEFDEF 68 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 ++ + +++ E++LK FK++D D NG I +EL + +N + L+ EE + Sbjct: 69 LSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVM-----INLGEKLTDEE-VE 122 Query: 137 LVFHKIDINNDGELTLEEFINGM 159 + + D++ DG++ EEF+ M Sbjct: 123 QMIKEADLDGDGQVNYEEFVKMM 145 Score = 60.0 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 46/91 (50%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 +G EF +L+ + + A + + + + FD +++G++ E + + ++ + Sbjct: 59 GNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD 118 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 ++++ K D DG+G ++ E + M M V+ Sbjct: 119 EEVEQMIKEADLDGDGQVNYEEFVKMMMTVR 149 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 6/104 (5%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 I+ E+ K F L+D DG+G I EL + ++ EE + + + Sbjct: 1 ADILSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPT------EEELQDMISE 54 Query: 142 IDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNG 185 +D + +G + +EF++ MAK + + + V NG Sbjct: 55 VDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNG 98 >2LM5-A nrPDB Length = 214 Score = 107 bits (268), Expect = 3e-24, Method: Composition-based stats. Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 28/187 (14%) Query: 10 DQKAVPTQETHVWYRTFMMEYP-------SGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 D + QE + +R F P S L+ F+ +L L L KAN +++ Sbjct: 41 DLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPEL--KANPFKERICR 98 Query: 63 TFDT----NKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 F T + F DFL+ ++ + + K + F+++D D +G++++ +L + Sbjct: 99 VFSTSPAKDSLSFEDFLDLLSVFSDTATPDI--KSHYAFRIFDFDDDGTLNREDLSRLVN 156 Query: 119 AVQALNGQQTLSPEEF---INLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDF 175 + LS E I+ + + DI+ DG + L EF + ++ +S DF Sbjct: 157 CLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH----------VISRSPDF 206 Query: 176 SNVLRVI 182 ++ +++ Sbjct: 207 ASSFKIV 213 >1TOP-A nrPDB Length = 162 Score = 107 bits (266), Expect = 4e-24, Method: Composition-based stats. Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 12/146 (8%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G + E T++ + G N + +D + D + G +DF EF Sbjct: 21 EFKAAFDMFDAD-GGGDISTKELGTVMRMLGQNPT-KEELDAIIEEVDEDGSGTIDFEEF 78 Query: 78 IAAVNLIMQE----KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + + M+E K E++L F+++D + +G ID EL ++ A EE Sbjct: 79 LVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVT------EE 132 Query: 134 FINLVFHKIDINNDGELTLEEFINGM 159 I + D NNDG + +EF+ M Sbjct: 133 DIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 2/121 (1%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLY 100 + L+++ ++ FD + G + E + ++ Q +++L + Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEV 65 Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 D DG+G+ID E L M V+ + EE + F D N DG + +EE + Sbjct: 66 DEDGSGTIDFEEFLVMM--VRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILR 123 Query: 161 K 161 Sbjct: 124 A 124 >4YZB-A nrPDB Length = 491 Score = 106 bits (264), Expect = 8e-24, Method: Composition-based stats. Identities = 43/165 (26%), Positives = 70/165 (42%), Gaps = 20/165 (12%) Query: 11 QKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKT----LLGLQGLNQKA------NKHID 58 K +ET + F M + G E L+ L+G + A ++ Sbjct: 330 SKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVE 389 Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 QV + D +K+GF+++ EF+ Q+L+ F ++DADG+G I +EL +F Sbjct: 390 QVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFG 449 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 + E V ++D NNDGE+ EEF + K Sbjct: 450 V--------SEVDSETWRRVLAEVDRNNDGEVDFEEFRQMLLKLC 486 >1S6I-A nrPDB Length = 188 Score = 106 bits (264), Expect = 8e-24, Method: Composition-based stats. Identities = 44/187 (23%), Positives = 78/187 (41%), Gaps = 15/187 (8%) Query: 12 KAVPTQETHVWYRTFMM--EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 + + +E F M SG T E K L G ++ I + + D +K Sbjct: 2 ERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVG-SELMESEIKDLMDAADIDKS 60 Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 G +D+ EFIAA + + + E+ L F +D DG+G I +E+ + Sbjct: 61 GTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQ--------ACKDFG 112 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDL----LEIVYKSFDFSNVLRVICNG 185 + I+ + +ID +NDG++ EF M K + + K+ + + L ++ NG Sbjct: 113 LDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRKRKGNGGIGRRTMRKTLNLRDALGLVDNG 172 Query: 186 KQPDMET 192 +E Sbjct: 173 SNQVIEG 179 >3Q5I-A nrPDB Length = 504 Score = 105 bits (263), Expect = 1e-23, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 64/173 (36%), Gaps = 17/173 (9%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMMEY--PSGLQTLHEFKTLLGLQGLNQKA----- 53 + + K +E F G E + + Sbjct: 336 LAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELK 395 Query: 54 --NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + +D + D +K+G++++ EFI+ E++L+ F L+D D +G I K Sbjct: 396 NVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKE 455 Query: 112 ELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 EL ++F T E+ N V + D N D + +EF++ M K D Sbjct: 456 ELANLFGL--------TSISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKICD 500 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 5/85 (5%) Query: 6 SIAGDQKAVPTQE-THVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 S+ D++ + ++E + F + SG T E L GL + K + V Sbjct: 423 SVCMDKQILFSEERLRRAFNLFDTD-KSGKITKEELAN---LFGLTSISEKTWNDVLGEA 478 Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKM 89 D NKD +DF EF++ ++ I K Sbjct: 479 DQNKDNMIDFDEFVSMMHKICDHKT 503 >2TN4-A nrPDB Length = 159 Score = 105 bits (263), Expect = 1e-23, Method: Composition-based stats. Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 12/146 (8%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G ++ E T++ + G + +D + D + G +DF EF Sbjct: 18 EFKAAFDMFDAD-GGGDISVKELGTVMRMLGQTPT-KEELDAIIEEVDEDGSGTIDFEEF 75 Query: 78 IAAVNLIMQE----KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + + M+E K E++L F+++D + +G ID EL ++F A + ++ EE Sbjct: 76 LVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRA-----SGEHVTDEE 130 Query: 134 FINLVFHKIDINNDGELTLEEFINGM 159 I + D NNDG + +EF+ M Sbjct: 131 -IESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLY 100 + L+++ ++ FD + G + E + ++ Q +++L + Sbjct: 3 QQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEV 62 Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFING 158 D DG+G+ID E L M V+ + EE + +F D N DG + EE Sbjct: 63 DEDGSGTIDFEEFLVMM--VRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEI 118 Score = 52.3 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+M + K F ++DADG G I EL + + ++ L + + ++D Sbjct: 11 LSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEEL------DAIIEEVDE 64 Query: 145 NNDGELTLEEFINGMAK 161 + G + EEF+ M + Sbjct: 65 DGSGTIDFEEFLVMMVR 81 >4MVF-A nrPDB Length = 506 Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 5/132 (3%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG + E L G QK I QV D+N G + + +F+AA ++ Sbjct: 374 SGTLSSQEILDGLKKIG-YQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKE 432 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 FK +D DGNG I EL +F + + ++ I+ + ++D+N DGE+ Sbjct: 433 VCLIPFKFFDIDGNGKISVEELKRIF----GRDDIENPLIDKAIDSLLQEVDLNGDGEID 488 Query: 152 LEEFINGMAKDQ 163 EF+ M+K + Sbjct: 489 FHEFMLMMSKLE 500 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGL-NQKANKHIDQVYNTF 64 + D++ +E + F +G ++ E K + G + N +K ID + Sbjct: 420 AATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEV 479 Query: 65 DTNKDGFVDFLEFIAAVNLI 84 D N DG +DF EF+ ++ + Sbjct: 480 DLNGDGEIDFHEFMLMMSKL 499 >5YPX-A nrPDB Length = 223 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 74/164 (45%), Gaps = 4/164 (2%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 QK E + + F+ +L + N + +D+V+ FD + D Sbjct: 38 QKHFTKTEVESLIICYKNLLEGLKMDRNLFRDILHQKF-NMTEDLLMDRVFRAFDKDSDS 96 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 ++ E++ +++ ++ +++K+++ F ++D +G+G I + E+ M + Sbjct: 97 YISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPTEEDP 156 Query: 131 PE---EFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYK 171 E + + + K+D ++D L+ ++F + + + LLE K Sbjct: 157 DEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLIEPLLLEAFGK 200 >3KHE-A nrPDB Length = 191 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 20/167 (11%) Query: 11 QKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGL----------NQKANKHID 58 K +ET + F + G E + + +D Sbjct: 31 SKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 90 Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + + D +++G++++ EF+ ++L F+ +D+DG+G I EL +F Sbjct: 91 HILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLFG 150 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDL 165 T +E + V + D NNDGE+ EEF+ M K D+ Sbjct: 151 V--------TEVDDETWHQVLQECDKNNDGEVDFEEFVEMMQKICDV 189 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 40/90 (44%), Gaps = 5/90 (5%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ-----QTLSPEEFIN 136 + + + ++L F+ D +G+G +D+ EL++ + + G + E ++ Sbjct: 31 SKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 90 Query: 137 LVFHKIDINNDGELTLEEFINGMAKDQDLL 166 + +D + +G + EF+ Q LL Sbjct: 91 HILQSVDFDRNGYIEYSEFVTVCMDKQLLL 120 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 4/79 (5%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 Q + + ++ F + SG T E L G+ + ++ QV D N DG Sbjct: 117 QLLLSRERLLAAFQQFDSD-GSGKITNEELG---RLFGVTEVDDETWHQVLQECDKNNDG 172 Query: 71 FVDFLEFIAAVNLIMQEKM 89 VDF EF+ + I K+ Sbjct: 173 EVDFEEFVEMMQKICDVKV 191 >5B8I-B nrPDB Length = 171 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 8/142 (5%) Query: 20 HVWYRTFMMEYP-SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFI 78 +W R ++ SG EF +L +N ++ FD + G VDF EF+ Sbjct: 22 RLWKRFMKLDRDKSGTIERDEFLSL-----PQVSSNPLSTRMIAIFDEDGGGDVDFQEFV 76 Query: 79 AAVNLIM-QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 + ++ + E+KL++ FK+YD D +G I EL + + N + + ++ ++ Sbjct: 77 SGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSN-LKDMQLQQIVDK 135 Query: 138 VFHKIDINNDGELTLEEFINGM 159 + D++ DG ++ EEF + Sbjct: 136 TIMEADLDGDGRISFEEFTRMV 157 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 38/93 (40%), Gaps = 16/93 (17%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 +L F D D +G+I+++E L + +S + D + G++ Sbjct: 21 DRLWKRFMKLDRDKSGTIERDEFLSL----------PQVSSNPLSTRMIAIFDEDGGGDV 70 Query: 151 TLEEFINGMAK------DQDLLEIVYKSFDFSN 177 +EF++G++ ++ L +K +D Sbjct: 71 DFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDR 103 >3O4Y-A nrPDB Length = 196 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 6/135 (4%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 + E G T + + L GL N D + + D++ G +D+ EF+AA I + Sbjct: 64 LDEEGKGNITKLQLRKGLERSGLMLPPN--FDLLLDQIDSDGSGNIDYTEFLAAA--IDR 119 Query: 87 EKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 ++ +KL + F+++D D +G I EL + G T + + ++D N Sbjct: 120 RQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNK-RGNITERDVNQVKKMIREVDKN 178 Query: 146 NDGELTLEEFINGMA 160 DG++ EF M Sbjct: 179 GDGKIDFYEFSEMMK 193 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 36/84 (42%), Gaps = 5/84 (5%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLL----GLQGLNQKANKHIDQVY 61 + A D++ + + + +R F ++ G T E +L + ++ + ++ Sbjct: 114 AAAIDRRQLSKKLIYCAFRVFDVD-NDGEITTAELAHVLFNGNKRGNITERDVNQVKKMI 172 Query: 62 NTFDTNKDGFVDFLEFIAAVNLIM 85 D N DG +DF EF + L + Sbjct: 173 REVDKNGDGKIDFYEFSEMMKLTL 196 >4RGJ-A nrPDB Length = 520 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 20/166 (12%) Query: 11 QKAVPTQETHVWYRTFMMEY--PSGLQTLHEF----KTLLGLQGL------NQKANKHID 58 K ET + F G +E K LL L+G N +D Sbjct: 362 SKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVD 421 Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 Q+ N+ D +++G++++ EF+ ++L+ FKL+D DG+G I NEL +F Sbjct: 422 QILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLF- 480 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 G +S E + V ++D NNDGE+ +EF + + K + Sbjct: 481 ------GLSDVSSECW-KTVLKEVDQNNDGEIDFKEFRDMLVKLCN 519 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 10/113 (8%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS-----PEEFIN 136 + + ++L FK D +G+G +D+NEL+ + + L G+ T E ++ Sbjct: 362 SKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVD 421 Query: 137 LVFHKIDINNDGELTLEEFINGMAKDQDL-----LEIVYKSFDFSNVLRVICN 184 + + ID++ +G + EF+ + L LE +K FD ++ N Sbjct: 422 QILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISAN 474 >2LMV-A nrPDB Length = 148 Score = 103 bits (256), Expect = 8e-23, Method: Composition-based stats. Identities = 37/144 (25%), Positives = 68/144 (47%), Gaps = 9/144 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F E +G E TL+ G N + D + + N +G ++F EF Sbjct: 11 EFKDAFVQFDKE-GTGKIATRELGTLMRTLGQNPTEAELQD-LIAEAENNNNGQLNFTEF 68 Query: 78 IAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + M+E E++++ FK++D DG+G I EL + +N + ++ EE I+ Sbjct: 69 CGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVM-----INLGEKVTDEE-ID 122 Query: 137 LVFHKIDINNDGELTLEEFINGMA 160 + + D + DG + EEF+ ++ Sbjct: 123 EMIREADFDGDGMINYEEFVWMIS 146 Score = 57.7 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 38/88 (43%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +G EF ++ Q + + + + FD + DGF+ E + + ++ ++ Sbjct: 60 NGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDE 119 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMA 119 ++ + D DG+G I+ E + M Sbjct: 120 EIDEMIREADFDGDGMINYEEFVWMISQ 147 >3LIJ-A nrPDB Length = 494 Score = 102 bits (254), Expect = 1e-22, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 66/173 (38%), Gaps = 17/173 (9%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQ-------GLNQ 51 + + K +ET F + + G E Sbjct: 327 LAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLP 386 Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + +D + D +++G++D+ EF+ + KL+ F+ +D DGNG I + Sbjct: 387 QIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVD 446 Query: 112 ELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 EL +F L+ ++ + +E + ID NNDG++ EEF + K Sbjct: 447 ELASVF----GLDHLESKTWKE----MISGIDSNNDGDVDFEEFCKMIQKLCS 491 Score = 53.1 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEF 134 + + + ++ ++L F+ D +G+G +D+ EL+D + + E Sbjct: 332 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE 391 Query: 135 INLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 ++ + D + +G + EF+ + LL Sbjct: 392 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLL 423 >2JNF-A nrPDB Length = 158 Score = 102 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 16/165 (9%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV 60 MG+ ++ +Q + +R F SG + + +L + G+ Q I Q+ Sbjct: 1 MGDVSKLSSNQVKL----LETAFRDFETPEGSGRVSTDQIGIILEVLGIQQT-KSTIRQL 55 Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIM-----QEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 + FD +G +DF F + E+M+Q+L+ F+LYD +GNG I + + + Sbjct: 56 IDEFDPFGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMRE 115 Query: 116 MFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 + + +TLS E+ ++ + +ID + G + EEF+ M Sbjct: 116 ILAEL-----DETLSSED-LDAMIDEIDADGSGTVDFEEFMGVMT 154 >3NCG-A nrPDB Length = 486 Score = 100 bits (250), Expect = 4e-22, Method: Composition-based stats. Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 12/140 (8%) Query: 27 MMEYPSGLQTLHEFKTLLGL------QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAA 80 M++ ++ HEF L G+ Q ID + D + G +++ EFIA+ Sbjct: 347 MLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIAS 406 Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 ++++ FK++D DG+G I EL +F + + L + Sbjct: 407 AIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSQADSSIQMEEL------ESIIE 460 Query: 141 KIDINNDGELTLEEFINGMA 160 ++D N DGE+ EF+ + Sbjct: 461 QVDNNKDGEVDFNEFVEMLQ 480 Score = 50.4 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 47/111 (42%), Gaps = 13/111 (11%) Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG--------QQT 128 + + + ++L F+ D + +G +D++EL+ + L G + Sbjct: 317 LLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEG 376 Query: 129 LSPEEFINLVFHKIDINNDGELTLEEFI-----NGMAKDQDLLEIVYKSFD 174 + E+ I+ + +D++ G + EFI + ++ +E +K FD Sbjct: 377 STIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFD 427 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 34/89 (38%), Gaps = 1/89 (1%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 SG EF + + + +++ + FD + G + E + Sbjct: 394 GSGSIEYSEF-IASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSQADSSIQM 452 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMA 119 ++L+ + D + +G +D NE ++M Sbjct: 453 EELESIIEQVDNNKDGEVDFNEFVEMLQN 481 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 8 AGDQKAVPTQE-THVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDT 66 A D+ + ++E ++ F + SG + E L + + + ++ + D Sbjct: 407 AIDRTILLSRERMERAFKMFDKD-GSGKISTKELFKLFSQADSSIQM-EELESIIEQVDN 464 Query: 67 NKDGFVDFLEFIAAVNLIMQEK 88 NKDG VDF EF+ + ++ + Sbjct: 465 NKDGEVDFNEFVEMLQNFVRNE 486 >3PM8-A nrPDB Length = 197 Score = 99.7 bits (247), Expect = 8e-22, Method: Composition-based stats. Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 5/132 (3%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG + E L G QK I QV D+N G + + +F+AA ++ Sbjct: 71 SGTLSSQEILDGLKKIG-YQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKE 129 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 FK +D DGNG I EL +F + + ++ I+ + ++D+N DGE+ Sbjct: 130 VCLIPFKFFDIDGNGKISVEELKRIF----GRDDIENPLIDKAIDSLLQEVDLNGDGEID 185 Query: 152 LEEFINGMAKDQ 163 EF+ M+K + Sbjct: 186 FHEFMLMMSKKK 197 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGL-NQKANKHIDQVYNTF 64 + D++ +E + F +G ++ E K + G + N +K ID + Sbjct: 117 AATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEV 176 Query: 65 DTNKDGFVDFLEFIAAVNLI 84 D N DG +DF EF+ ++ Sbjct: 177 DLNGDGEIDFHEFMLMMSKK 196 >3QRX-A nrPDB Length = 169 Score = 97.8 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 37/160 (23%), Positives = 65/160 (40%), Gaps = 9/160 (5%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 + K QE + F + SG E K + G K + I ++ + Sbjct: 14 DQKKGRVGLTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRALGFEPK-KEEIKKMIS 71 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 D + G +DF EF+ + M E +++ F+L+D D +G+I +L + + Sbjct: 72 EIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELG 131 Query: 122 ALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 EE + + + D N+D E+ +EFI M K Sbjct: 132 ENLT------EEELQEMIAEADRNDDNEIDEDEFIRIMKK 165 Score = 36.9 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + SG T+ + + + G N + + ++ D N D +D Sbjct: 99 SREEILKAFRLF-DDDNSGTITIKDLRRVAKELGENLT-EEELQEMIAEADRNDDNEIDE 156 Query: 75 LEFIAAVNLIM 85 EFI + Sbjct: 157 DEFIRIMKKTS 167 >2LAP-A nrPDB Length = 167 Score = 95.9 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 60/150 (40%), Gaps = 12/150 (8%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E +R F + G + + G + I+ + + N G VDF + Sbjct: 25 EELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGHVDFDD 82 Query: 77 FIAAVNLIMQEKME-----QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 F+ + + + ++L+ F+ +D +G+G I +EL + + Sbjct: 83 FVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHR--- 139 Query: 132 EEFINLVFHKIDINNDGELTLEEFINGMAK 161 I + +D+N DG + EEF+ M++ Sbjct: 140 --DIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 K +A + +E +R F G + E + + +Q ++ I+++ Sbjct: 90 KLLAETADMIGVKELRDAFREFDTN-GDGEISTSELREAMRKLLGHQVGHRDIEEIIRDV 148 Query: 65 DTNKDGFVDFLEFIAAVNL 83 D N DG VDF EF+ ++ Sbjct: 149 DLNGDGRVDFEEFVRMMSR 167 >3L19-A nrPDB Length = 214 Score = 95.1 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 60/173 (34%), Gaps = 17/173 (9%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQ-------GLNQ 51 + + K +ET F + + G E Sbjct: 44 LAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLP 103 Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + +D + D +++G++D+ EF+ + KL+ F+ +D DGNG I + Sbjct: 104 QIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVD 163 Query: 112 ELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 EL +F + + ID NNDG++ EEF + K Sbjct: 164 ELASVFGL--------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLCS 208 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEF 134 + + + ++ ++L F+ D +G+G +D+ EL+D + + E Sbjct: 49 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE 108 Query: 135 INLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 ++ + D + +G + EF+ + LL Sbjct: 109 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLL 140 >2LHI-A nrPDB Length = 176 Score = 94.7 bits (234), Expect = 3e-20, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 74/156 (47%), Gaps = 10/156 (6%) Query: 7 IAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDT 66 + + E + F + +G + E T++ GL+ + ++ + N D Sbjct: 1 GSSNLTEEQIAEFKEAFALFDKD-NNGSISSSELATVMRSLGLSP-SEAEVNDLMNEIDV 58 Query: 67 NKDGFVDFLEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 + + ++F EF+A ++ ++ EQ+L FK++D +G+G I EL + ++ Sbjct: 59 DGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI----- 113 Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + L+ E ++ + ++ + GE+ +++F ++K Sbjct: 114 GEKLTDAE-VDDMLREV-SDGSGEINIQQFAALLSK 147 >4DS7-A nrPDB Length = 147 Score = 93.2 bits (230), Expect = 7e-20, Method: Composition-based stats. Identities = 32/145 (22%), Positives = 71/145 (48%), Gaps = 10/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + SG + E T++ GL+ + D + N D + + ++F EF Sbjct: 12 EFKEAFALFDKD-NSGSISASELATVMRSLGLSPSEAEVAD-LMNEIDVDGNHAIEFSEF 69 Query: 78 IAAVNLIMQ-EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 +A ++ ++ EQ+L FK++D +G+G I EL + ++ + L+ E ++ Sbjct: 70 LALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI-----GEKLTDAE-VD 123 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + ++ + GE+ +++F ++K Sbjct: 124 EMLREV-SDGSGEINIKQFAALLSK 147 Score = 57.3 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 ++ + E+ + K F L+D D +GSI +EL + ++ E + + + Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLG------LSPSEAEVADLMN 54 Query: 141 KIDINNDGELTLEEFINGMAK-------DQDLLEIVYKSFD 174 +ID++ + + EF+ M++ +Q+LLE +K FD Sbjct: 55 EIDVDGNHAIEFSEFLALMSRQLKCNDSEQELLEA-FKVFD 94 >2M29-A nrPDB Length = 171 Score = 90.5 bits (223), Expect = 5e-19, Method: Composition-based stats. Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 12/146 (8%) Query: 20 HVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIA 79 + F + G E + G + ++ V GFVDF EF+ Sbjct: 31 QAAFEEFDTDQD-GYIGYRELGDCMRTLGYMPTEMELLE-VSQHVKMRMGGFVDFEEFVE 88 Query: 80 AVNLIMQEKME-----QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF 134 ++ ++E+ ++L+ F+ +D D +G I EL A AL G+ E Sbjct: 89 LISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQ---AAPALLGEPLEGTE-- 143 Query: 135 INLVFHKIDINNDGELTLEEFINGMA 160 ++ + ++D+N DG + +EF+ ++ Sbjct: 144 LDEMLREMDLNGDGTIDFDEFVMMLS 169 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E + +R F + G T+ E + +D++ D N DG +DF E Sbjct: 105 RELRIAFREFDKDRD-GRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDE 163 Query: 77 FIAAVN 82 F+ ++ Sbjct: 164 FVMMLS 169 >2E6W-A nrPDB Length = 100 Score = 90.1 bits (222), Expect = 7e-19, Method: Composition-based stats. Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 6/86 (6%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL------SPEEFINLVFH 140 + +KLKW F LYD + +G I K E+L + ++ + G+ T +P E + F Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 141 KIDINNDGELTLEEFINGMAKDQDLL 166 K+D N DG +T+EEF+ KD++++ Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIM 90 Score = 30.8 bits (68), Expect = 0.39, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 20/42 (47%) Query: 125 GQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 G + E + F+ DIN DG +T EE + M D++ Sbjct: 1 GSHMGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMM 42 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 23/77 (29%), Gaps = 11/77 (14%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQG-----------LNQKANKHIDQVYNT 63 E W G T E ++ +H+++ + Sbjct: 6 TVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEK 65 Query: 64 FDTNKDGFVDFLEFIAA 80 D N+DG V EF+ A Sbjct: 66 MDRNQDGVVTIEEFLEA 82 >1LKJ-A nrPDB Length = 146 Score = 89.3 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 30/145 (20%), Positives = 72/145 (49%), Gaps = 10/145 (6%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + +G + E T++ GL+ + ++ + N D + + ++F EF Sbjct: 11 EFKEAFALFDKD-NNGSISSSELATVMRSLGLSP-SEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 78 IAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 +A ++ ++ EQ+L FK++D +G+G I EL + ++ + L+ E ++ Sbjct: 69 LALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI-----GEKLTDAE-VD 122 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + ++ + GE+ +++F ++K Sbjct: 123 DMLREV-SDGSGEINIQQFAALLSK 146 >3KF9-A nrPDB Length = 149 Score = 88.2 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 35/148 (23%), Positives = 58/148 (39%), Gaps = 9/148 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + F + SG E K + G K + I ++ D + G +DF Sbjct: 6 QKQEIREAFDLFDTD-GSGTIDAKELKVAMRALGFEPK-KEEIKKMIADIDKDGSGTIDF 63 Query: 75 LEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 EF+ + M E +++ F+L+D D G I L + + +E Sbjct: 64 EEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMT------DE 117 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + + D + DGE+ EEF M K Sbjct: 118 ELQEMIDEADRDGDGEVNEEEFFRIMKK 145 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G + K + G N ++ + ++ + D + DG V+ Sbjct: 79 SREEIMKAFRLF-DDDETGKISFKNLKRVAKELGENMT-DEELQEMIDEADRDGDGEVNE 136 Query: 75 LEFIAAVNLIM 85 EF + Sbjct: 137 EEFFRIMKKTS 147 >5D43-A nrPDB Length = 178 Score = 87.8 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + F + SG + E K + G + + + ++ + D G + F Sbjct: 29 QKQEVREAFDLFDSD-GSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKISF 86 Query: 75 LEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 +F+A + M EK ++++ F+L+D D G I L + + ++L+ EE Sbjct: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-----GESLTDEE 141 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + + D + DGE+ EEF+ M K Sbjct: 142 -LQEMIDEADRDGDGEVNEEEFLKIMKK 168 Score = 53.1 bits (126), Expect = 9e-08, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 40/90 (44%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +G + ++F ++ + + + I + + FD ++ G + F N + + ++ Sbjct: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDE 140 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 +L+ D DG+G +++ E L + Sbjct: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 >3AAJ-A nrPDB Length = 167 Score = 87.4 bits (215), Expect = 4e-18, Method: Composition-based stats. Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 15/143 (10%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG+ + E + L + + + FD V+F EF I + Sbjct: 18 SGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQN-- 75 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 F+ YD D +G IDKNEL + ++F +++ K D G++ Sbjct: 76 ----VFRTYDRDNSGMIDKNELKQALSGYR--------LSDQFHDILIRKFDRQGRGQIA 123 Query: 152 LEEFINGMAKDQDLLEIVYKSFD 174 ++FI G Q L +I ++ +D Sbjct: 124 FDDFIQGCIVLQRLTDI-FRRYD 145 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 11/91 (12%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG+ +E K L L +++ D + FD G + F +FI ++ Q Sbjct: 85 SGMIDKNELKQALSGYRL---SDQFHDILIRKFDRQGRGQIAFDDFIQGCIVL------Q 135 Query: 92 KLKWYFKLYDADGNGSI--DKNELLDMFMAV 120 +L F+ YD D +G I + L M ++ Sbjct: 136 RLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 166 Score = 33.5 bits (75), Expect = 0.065, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 29/88 (32%), Gaps = 6/88 (6%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F+ D D +G I EL + + D N + EF Sbjct: 10 FQRVDKDRSGVISDTELQQALSNGTWTPFNPVT-----VRSIISMFDRENKAGVNFSEFT 64 Query: 157 NGMAKDQDLLEIVYKSFDFSNVLRVICN 184 G+ K + V++++D N + N Sbjct: 65 -GVWKYITDWQNVFRTYDRDNSGMIDKN 91 >2GGM-A nrPDB Length = 172 Score = 83.9 bits (206), Expect = 4e-17, Method: Composition-based stats. Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + F + +G + E K + G K + I ++ + D G ++F Sbjct: 29 QKQEIREAFDLFDAD-GTGTIDVKELKVAMRALGFEPK-KEEIKKMISEIDKEGTGKMNF 86 Query: 75 LEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 +F+ + M EK ++++ FKL+D D G I L + + + L+ EE Sbjct: 87 GDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-----GENLTDEE 141 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + + D + DGE++ +EF+ M K Sbjct: 142 -LQEMIDEADRDGDGEVSEQEFLRIMKK 168 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 + +E ++ F + +G + K + G N ++ + ++ + D + DG Sbjct: 98 SEKDTKEEILKAFKLF-DDDETGKISFKNLKRVAKELGENLT-DEELQEMIDEADRDGDG 155 Query: 71 FVDFLEFIAAVNLIM 85 V EF+ + Sbjct: 156 EVSEQEFLRIMKKTS 170 >5ZOR-A nrPDB Length = 149 Score = 82.0 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 64/148 (43%), Gaps = 8/148 (5%) Query: 13 AVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV 72 A+ ++ + F + SG E + G +++ + +TN +G + Sbjct: 3 ALTDEQIREAFNLFDAD-GSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLI 61 Query: 73 DFLEFIAAV-NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 ++ EF V + + Q+ +++ F+L+D D G I L ++ + G Sbjct: 62 EYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPG------ 115 Query: 132 EEFINLVFHKIDINNDGELTLEEFINGM 159 ++ + + + D + DGE++ EEF + M Sbjct: 116 DDVLQEMIAEADEDGDGEVSFEEFKSVM 143 Score = 53.1 bits (126), Expect = 9e-08, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 39/91 (42%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +GL EF+ ++ + + + + + + + FD +K G + F L+ + + Sbjct: 58 NGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDD 117 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 L+ D DG+G + E + M ++ Sbjct: 118 VLQEMIAEADEDGDGEVSFEEFKSVMMQMRG 148 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 45/109 (41%), Gaps = 6/109 (5%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM-EQKLKWYFKLYDADGNGSIDKN 111 ++ I + +N FD + G +D E A+ + + +++ + + + NG I+ Sbjct: 5 TDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYG 64 Query: 112 ELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 E M + A Q SPEE + F D++ G+++ Sbjct: 65 EFERMVKSRMA----QKDSPEEVL-KAFQLFDLDKKGKISFANLKEVAK 108 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M +++++ F L+DADG+G+ID E+ + + P + + ++ Sbjct: 1 MAALTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDL-----PRDEVERTVRSMNT 55 Query: 145 NNDGELTLEEFINGMA 160 N +G + EF + Sbjct: 56 NANGLIEYGEFERMVK 71 >1JFJ-A nrPDB Length = 134 Score = 80.5 bits (197), Expect = 4e-16, Method: Composition-based stats. Identities = 36/107 (33%), Positives = 57/107 (53%), Gaps = 5/107 (4%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ D N DG V + E A V+ K EQ L+ FK DADGNG ID+NE Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 117 FMAVQALNGQQTLSPEEF-INLVFHKIDINNDGELTLEEFINGMAKD 162 + ++Q Q LS ++ + +++ +D++ DG+LT EE + K Sbjct: 62 YGSIQG----QDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKH 104 Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 32/133 (24%), Positives = 52/133 (39%), Gaps = 14/133 (10%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 G + E K + + K + + ++ + D + +G +D EF I + + Sbjct: 13 GDGAVSYEEVKAFVSKKRA-IKNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSIQGQDLS 71 Query: 91 QK---LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 LK +KL D DG+G + K E+ F E+ V D N D Sbjct: 72 DDKIGLKVLYKLMDVDGDGKLTKEEVTSFFK---------KHGIEKVAEQVMK-ADANGD 121 Query: 148 GELTLEEFINGMA 160 G +TLEEF+ Sbjct: 122 GYITLEEFLEFSL 134 Score = 34.6 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 5/56 (8%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMA-----KDQDLLEIVYKSFDFSNVLRVICN 184 +F +ID+N DG ++ EE ++ K++ LL++++KS D + N Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQN 56 >2OBH-A nrPDB Length = 143 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + F + +G + E K + G K + I ++ + D G ++F Sbjct: 4 QKQEIREAFDLFDAD-GTGTIDVKELKVAMRALGFEPK-KEEIKKMISEIDKEGTGKMNF 61 Query: 75 LEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 +F+ + M EK ++++ FKL+D D G I L + + + L+ EE Sbjct: 62 GDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-----GENLTDEE 116 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + + D + DGE++ +EF+ M K Sbjct: 117 -LQEMIDEADRDGDGEVSEQEFLRIMKK 143 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 6/75 (8%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 E+ +Q+++ F L+DADG G+ID EL A+ + E I + +ID Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK------EEIKKMISEIDKE 54 Query: 146 NDGELTLEEFINGMA 160 G++ +F+ M Sbjct: 55 GTGKMNFGDFLTVMT 69 >2BEC-A nrPDB Length = 202 Score = 78.1 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 65/177 (36%), Gaps = 24/177 (13%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEY-PSGLQTLHEFKTLLGLQGLNQKANKHIDQVY 61 +G SI + + +R ++ G + + + + L N D++ Sbjct: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL-----AVNPLGDRII 67 Query: 62 NTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ-----------------KLKWYFKLYDADG 104 +F + VDF F+ + + E KL + F+LYD D Sbjct: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 +G I ++E+L + + + + E + + D + DG ++ EF + K Sbjct: 128 DGKISRHEMLQVLRLMVGVQVTEE-QLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 Score = 35.8 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 36/79 (45%), Gaps = 8/79 (10%) Query: 19 THVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN----TFDTNKDGFVDF 74 H ++ + ++ G + HE +L L Q + ++ + + D + DG V F Sbjct: 116 LHYAFQLYDLDRD-GKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 Query: 75 LEFIAAVNLIMQEKMEQKL 93 +EF ++ + +EQK+ Sbjct: 175 VEFTKSLE---KMDVEQKM 190 Score = 33.8 bits (76), Expect = 0.053, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 37/92 (40%), Gaps = 8/92 (8%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNL-----IMQEKMEQKLKWYFK 98 + + +D ++DG + E + + L + +E++E + Sbjct: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQ 162 Query: 99 LYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 D DG+G++ E +++ ++ +Q +S Sbjct: 163 EADEDGDGAVSFVEFTK---SLEKMDVEQKMS 191 >2JNX-A nrPDB Length = 134 Score = 77.8 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ D N DG V + E A V+ K EQ L+ FK D DGNG ID E Sbjct: 2 AEALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKF 61 Query: 117 FMAVQALNGQQTLSPEEF-INLVFHKIDINNDGELTLEEFINGMAK 161 AV+ +Q LS E+ + +++ +D + DG+LT EE K Sbjct: 62 AAAVK----EQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKK 103 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 14/131 (10%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 G + E K + + K + + ++ D + +G +D EF + ++ + Sbjct: 13 GDGSVSYEEVKAFVSSKRP-IKNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAAVKEQDLS 71 Query: 91 QK---LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 + LK +KL DADG+G + K E+ F E+ ++ + D N D Sbjct: 72 DEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY---------EKVVDQIMK-ADANGD 121 Query: 148 GELTLEEFING 158 G +TLEEF+ Sbjct: 122 GYITLEEFLAF 132 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 14/86 (16%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 FK DA+G+GS+ E+ + + + E+ + L+F IDI+ +GE+ L EF Sbjct: 6 FKQLDANGDGSVSYEEVKAFVSSKRPIKN------EQLLQLIFKAIDIDGNGEIDLAEFT 59 Query: 157 NGMA--KDQDL------LEIVYKSFD 174 A K+QDL L+I+YK D Sbjct: 60 KFAAAVKEQDLSDEKVGLKILYKLMD 85 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 26/47 (55%), Gaps = 5/47 (10%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMA-----KDQDLLEIVYKSFDF 175 +F ++D N DG ++ EE ++ K++ LL++++K+ D Sbjct: 1 MAEALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDI 47 >2HF5-A nrPDB Length = 68 Score = 77.4 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNEL 113 + + N D + +G +DF EF+ + M++ E++++ F+++D DGNG I EL Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 114 LDMFMAV 120 + + Sbjct: 61 RHVMTNL 67 Score = 45.0 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L+ DADGNG+ID E L M EE I F D + +G ++ Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMK-----DTDSEEEIREAFRVFDKDGNGYIS 56 Query: 152 LEEFINGMA 160 E + M Sbjct: 57 AAELRHVMT 65 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 24/55 (43%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 +G EF T++ + + + + I + + FD + +G++ E + + Sbjct: 14 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 68 Score = 33.1 bits (74), Expect = 0.079, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 23/46 (50%), Gaps = 6/46 (13%) Query: 135 INLVFHKIDINNDGELTLEEFINGMAK------DQDLLEIVYKSFD 174 + + +++D + +G + EF+ MA+ ++ + ++ FD Sbjct: 3 LQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 48 >2LHH-A nrPDB Length = 128 Score = 77.4 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 53/113 (46%), Gaps = 3/113 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + +G + E T++ GL+ + ++ + N D + + ++F EF Sbjct: 11 EFKEAFALFDKD-NNGSISSSELATVMRSLGLSP-SEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 78 IAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 +A ++ ++ EQ+L FK++D +G+G I EL + ++ L Sbjct: 69 LALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEL 121 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 14/100 (14%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + + E+ + K F L+D D NGSI +EL + ++ E +N + ++ Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLG------LSPSEAEVNDLMNE 54 Query: 142 IDINNDGELTLEEFINGMAK-------DQDLLEIVYKSFD 174 ID++ + ++ EF+ M++ +Q+LLE +K FD Sbjct: 55 IDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEA-FKVFD 93 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 42/113 (37%), Gaps = 5/113 (4%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 L ++ + + FD + +G + E + + E ++ D DGN Sbjct: 3 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQ 62 Query: 108 IDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 I+ +E L + ++ E+ + F D N DG ++ E + + Sbjct: 63 IEFSEFLALMS-----RQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLT 110 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 26/61 (42%) Query: 34 LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKL 93 EF L+ Q + + + + + + FD N DG + E + I ++ + +L Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEL 121 Query: 94 K 94 + Sbjct: 122 E 122 >5E1J-A nrPDB Length = 741 Score = 76.2 bits (186), Expect = 8e-15, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Query: 73 DFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 F E +A M + + L+ F L D+D NG IDKN+ + +F + +S E Sbjct: 307 SFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKE 366 Query: 133 EFINLVFHKIDINNDGELTLEEFINGMAKD 162 EF L+F ++D D ++ +EF + Sbjct: 367 EF-GLIFDELDDTRDFKINKDEFADLCQAI 395 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 43/104 (41%), Gaps = 11/104 (10%) Query: 35 QTLHEFKTLLGLQ--GLNQKANKHIDQVYNTFDTNKDGFVD-------FLEFIAAVNLIM 85 FK L Q G++Q + +++ + D++K+G +D F + + Sbjct: 303 VVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNY--RTL 360 Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 + +++ F D + I+K+E D+ A+ ++ + Sbjct: 361 PKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEV 404 >2KN2-A nrPDB Length = 92 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 6/75 (8%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M E++LK FK++D D NG I +EL + +N + L+ EE + + + D+ Sbjct: 3 MDTDAEEELKEAFKVFDKDQNGYISASELRHVM-----INLGEKLTDEE-VEQMIKEADL 56 Query: 145 NNDGELTLEEFINGM 159 + DG++ EEF+ M Sbjct: 57 DGDGQVNYEEFVKMM 71 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 38/72 (52%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSID 109 + A + + + + FD +++G++ E + + ++ +++++ K D DG+G ++ Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 63 Query: 110 KNELLDMFMAVQ 121 E + M M V+ Sbjct: 64 YEEFVKMMMTVR 75 >1FW4-A nrPDB Length = 71 Score = 74.3 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 E++++ F+++D DGNG I EL + + + L+ EE ++ + + DI+ Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VDEMIREADID 54 Query: 146 NDGELTLEEFINGMAK 161 DG++ EEF+ M Sbjct: 55 GDGQVNYEEFVQMMTA 70 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 34/70 (48%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSID 109 + + + I + + FD + +G++ E + + ++ ++++ + D DG+G ++ Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 110 KNELLDMFMA 119 E + M A Sbjct: 61 YEEFVQMMTA 70 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G + E + ++ G ++ +D++ D + DG V++ Sbjct: 4 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 61 Query: 75 LEFIAAVNLI 84 EF+ + Sbjct: 62 EEFVQMMTAK 71 >5MWC-D nrPDB Length = 311 Score = 73.9 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 39/82 (47%), Gaps = 6/82 (7%) Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 + A +L E++L F+ +D DG+G ID+ E + + L+ E+ + Sbjct: 138 VMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIR-----LTGEQLTDEDP-DE 191 Query: 138 VFHKIDINNDGELTLEEFINGM 159 +F D + +G + +EF+ + Sbjct: 192 IFGDSDTDKNGRIDFDEFLKMV 213 Score = 73.9 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 35/70 (50%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + + + + + TFD + DGF+D EF + L ++ ++ F D D NG ID + Sbjct: 148 PSEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFD 207 Query: 112 ELLDMFMAVQ 121 E L M VQ Sbjct: 208 EFLKMVENVQ 217 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Query: 2 GNGKSIAGDQKAV--PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQ 59 +G +A A+ +E +RTF + G EF ++ L G ++ D+ Sbjct: 134 ADGPVMANSLTAMVPSEEELSECFRTFDKD-GDGFIDREEFGGIIRLTGEQLT-DEDPDE 191 Query: 60 VYNTFDTNKDGFVDFLEFIAAV 81 ++ DT+K+G +DF EF+ V Sbjct: 192 IFGDSDTDKNGRIDFDEFLKMV 213 >2BL0-C nrPDB Length = 142 Score = 73.9 bits (180), Expect = 5e-14, Method: Composition-based stats. Identities = 37/146 (25%), Positives = 62/146 (42%), Gaps = 10/146 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 E + F E +G T +T+L G+ + ++++N D +G + F Sbjct: 4 QVSEFKEAFELFDSER-TGFITKEGLQTVLKQFGVRVEPAAF-NEMFNEADATGNGKIQF 61 Query: 75 LEFIAAVNLIMQEKMEQK-LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 EF++ + M++ + L+ F+ +D +G G I K L D LN L P E Sbjct: 62 PEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDAL-----LNLGDRLKPHE 116 Query: 134 FINLVFHKIDINNDGELTLEEFINGM 159 F F I G++ + FIN M Sbjct: 117 FAE--FLGITETEKGQIRYDNFINTM 140 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 39/89 (43%), Gaps = 12/89 (13%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F+L+D++ G I K L + N +F++ D +G++ Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAF------NEMFNEADATGNGKIQ 60 Query: 152 LEEFINGMAK------DQDLLEIVYKSFD 174 EF++ M + +D+L +++FD Sbjct: 61 FPEFLSMMGRRMKQTTSEDILRQAFRTFD 89 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 28/99 (28%), Gaps = 5/99 (5%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + + FD+ + GF+ + F DA GNG I Sbjct: 3 DQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQFP 62 Query: 112 ELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 E L M + E+ + F D G + Sbjct: 63 EFLSMMGRRMKQ-----TTSEDILRQAFRTFDPEGTGYI 96 >4N5X-A nrPDB Length = 199 Score = 73.9 bits (180), Expect = 5e-14, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 13/156 (8%) Query: 8 AGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN 67 A Q A ++ G+ + E + L G+ + ++++ T D N Sbjct: 13 AASQDAEQPTRYETLFQALDRN-GDGVVDIGELQEGLRNLGIPLGQDAE-EKIFTTGDVN 70 Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 KDG +DF EF+ + + E+K+K FK D + +G I+ +E+ VQ+L Sbjct: 71 KDGKLDFEEFMKYL-----KDHEKKMKLAFKSLDKNNDGKIEASEI------VQSLQTLG 119 Query: 128 TLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 E+ L+ ID++ + E+ + + Sbjct: 120 LTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNP 155 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 6/106 (5%) Query: 76 EFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI 135 +F+ + + + F+ D +G+G +D EL + + GQ Sbjct: 7 DFVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE------ 60 Query: 136 NLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRV 181 +F D+N DG+L EEF+ + + +++ +KS D +N ++ Sbjct: 61 EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKI 106 >4ZCV-A nrPDB Length = 165 Score = 72.8 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 60/133 (45%), Gaps = 12/133 (9%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 G+ + E + L G+ + ++++ T D NKDG +DF EF+ + + E Sbjct: 26 GDGVVDIGELQEGLRNLGIPLGQDAE-EKIFTTGDVNKDGKLDFEEFMKYL-----KDHE 79 Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 +K+K FK D + +G I+ +E+ VQ+L E+ L+ ID++ + Sbjct: 80 KKMKLAFKSLDKNNDGKIEASEI------VQSLQTLGLTISEQQAELILQSIDVDGTMTV 133 Query: 151 TLEEFINGMAKDQ 163 E+ + + Sbjct: 134 DWNEWRDYFLFNP 146 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 + + + ++ D N DG VD E + + + + F D + +G + Sbjct: 7 QDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKL 66 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 D E + E+ + L F +D NNDG++ E + + Sbjct: 67 DFEEFMKYLK-----------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ 107 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 10/80 (12%), Positives = 29/80 (36%), Gaps = 2/80 (2%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 ++ + +++ G E L GL + + + + + D + VD+ Sbjct: 79 EKKMKLAFKSLDKN-NDGKIEASEIVQSLQTLGLTI-SEQQAELILQSIDVDGTMTVDWN 136 Query: 76 EFIAAVNLIMQEKMEQKLKW 95 E+ +E+ +++ Sbjct: 137 EWRDYFLFNPVTDIEEIIRF 156 >2KZ2-A nrPDB Length = 94 Score = 72.8 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 42/80 (52%), Gaps = 6/80 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 +L+ E++++ F++ D DGNG I EL + + + L+ EE ++ + + Sbjct: 20 SLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNL-----GEKLTDEE-VDEMIRE 73 Query: 142 IDINNDGELTLEEFINGMAK 161 DI+ DG++ EEF+ M Sbjct: 74 ADIDGDGQVNYEEFVQMMTA 93 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 38/80 (47%), Gaps = 4/80 (5%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKL 99 F++L+ + + + I + + D + +G++ E + + ++ ++++ + Sbjct: 18 FQSLMK----DTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIRE 73 Query: 100 YDADGNGSIDKNELLDMFMA 119 D DG+G ++ E + M A Sbjct: 74 ADIDGDGQVNYEEFVQMMTA 93 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 30/70 (42%), Gaps = 2/70 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R + +G + E + ++ G ++ +D++ D + DG V++ Sbjct: 27 SEEEIREAFRVEDKD-GNGYISAAELRHVMTNLGEKLT-DEEVDEMIREADIDGDGQVNY 84 Query: 75 LEFIAAVNLI 84 EF+ + Sbjct: 85 EEFVQMMTAK 94 >3E3R-A nrPDB Length = 204 Score = 72.4 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 33/144 (22%), Positives = 57/144 (39%), Gaps = 7/144 (4%) Query: 19 THVWYRTFMMEYPSGLQTLH--EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 R F G ++L EF+ L GL + V +D N G +D E Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQ-AEAEGVCRKWDRNGSGTLDLEE 94 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF--MAVQALNGQQTLSPEEF 134 F+ A+ M + E + F D G+G + ++L ++ A + + + +E Sbjct: 95 FLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEW-TEDEV 153 Query: 135 INLVFHKID-INNDGELTLEEFIN 157 + D DG++TL EF + Sbjct: 154 LRRFLDNFDSSEKDGQVTLAEFQD 177 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 34/89 (38%), Gaps = 11/89 (12%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q L +F+ D DG+ S+D +E Q L + + V K D N G L Sbjct: 37 QGLARFFRQLDRDGSRSLDADEFR------QGLAKLGLVLDQAEAEGVCRKWDRNGSGTL 90 Query: 151 TLEEFIN-----GMAKDQDLLEIVYKSFD 174 LEEF+ + ++ + D Sbjct: 91 DLEEFLRALRPPMSQAREAVIAAAFAKLD 119 >5E37-A nrPDB Length = 356 Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 6/87 (6%) Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA----LNGQQTLSPE 132 F ++ + KME+ L+ FK+ D DGNG ID+ EL ++ ++++ + Q L PE Sbjct: 16 FEGLMDDASKAKMEE-LERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWL-PE 73 Query: 133 EFINLVFHKIDINNDGELTLEEFINGM 159 + + + D+N DG ++ EEF + Sbjct: 74 DELERCMEQYDVNKDGVISFEEFKQII 100 Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 65/189 (34%), Gaps = 7/189 (3%) Query: 1 MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV 60 M +G+ Q +P E + + G+ + EFK ++ L + + Sbjct: 58 MESGEVYMMSQHWLPEDELERCMEQYDVN-KDGVISFEEFKQIIYDGLLLEGTLAEYESA 116 Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 120 + D + +G + E + +KL ++YD D +G I+ E L MF Sbjct: 117 FKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNS 176 Query: 121 ---QALNGQQTLSPEEFINLVFHKID-INNDGELTL--EEFINGMAKDQDLLEIVYKSFD 174 E +D + D L EE ++ + D L +V+ + Sbjct: 177 LLDLKDMTTYMTLDEAGAGSSGSLVDAVEGDMTLIFSEEELDALISANPDKLVVVFGALT 236 Query: 175 FSNVLRVIC 183 + + + Sbjct: 237 WCRPCKGMQ 245 Score = 57.7 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 19/145 (13%), Positives = 47/145 (32%), Gaps = 42/145 (28%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM---------EQKLKWYFKLYDADGN 105 + +++ + D + +G +D E + + ++ E +L+ + YD + + Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKD 88 Query: 106 GSIDKNELLDMFMAVQALNG--------------------------------QQTLSPEE 133 G I E + L G +S E+ Sbjct: 89 GVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLEK 148 Query: 134 FINLVFHKIDINNDGELTLEEFING 158 ++ + D ++ G++ EF+ Sbjct: 149 LVD-LMQMYDKDDSGQIEFPEFLLM 172 Score = 27.3 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 18/44 (40%) Query: 121 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 + L + + E + F D++ +G + EE N + + Sbjct: 17 EGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMES 60 >2E30-A nrPDB Length = 195 Score = 71.2 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 61/169 (36%), Gaps = 24/169 (14%) Query: 11 QKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 + + Y F + + +G + +F+ + L N D++ N F Sbjct: 20 ETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPEL-----AINPLGDRIINAFFPEG 74 Query: 69 DGFVDFLEFIAAVNLIMQEKMEQK----------------LKWYFKLYDADGNGSIDKNE 112 + V+F F+ + + +K L + F+LYD D + I ++E Sbjct: 75 EDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDE 134 Query: 113 LLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 LL + + +N + + D + D ++ EF+ + K Sbjct: 135 LLQVLRMMVGVNISDEQLGS-IADRTIQEADQDGDSAISFTEFVKVLEK 182 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 35/86 (40%), Gaps = 8/86 (9%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGL-QGLNQKANKH---IDQVYNTFDTNKDGF 71 + + H +R + ++ + E +L + G+N + D+ D + D Sbjct: 112 SNKLHFAFRLYDLDKDE-KISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSA 170 Query: 72 VDFLEFIAAVNLIMQEKMEQKLKWYF 97 + F EF+ + + +EQK+ F Sbjct: 171 ISFTEFVKVLEKV---DVEQKMSIRF 193 Score = 34.2 bits (77), Expect = 0.041, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 38/117 (32%), Gaps = 6/117 (5%) Query: 14 VPTQETHVWYRTFMMEYPSGL-QTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV 72 P E V +R FM +E + + + + +D +KD + Sbjct: 71 FPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKI 130 Query: 73 DFLEFIAAVNL-----IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 E + + + I E++ + D DG+ +I E + + V Sbjct: 131 SRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQ 187 >2AMI-A nrPDB Length = 96 Score = 70.1 bits (170), Expect = 6e-13, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 39/75 (52%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADG 104 G GL ++ + I + ++ FDT+ G +D E A+ + E ++++K D DG Sbjct: 20 GRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDG 79 Query: 105 NGSIDKNELLDMFMA 119 +G+ID E L M A Sbjct: 80 SGTIDFEEFLTMMTA 94 Score = 60.8 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ +Q+++ F L+D DG+G+ID EL A+ + E I + +ID Sbjct: 24 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK------EEIKKMISEIDK 77 Query: 145 NNDGELTLEEFINGMAK 161 + G + EEF+ M Sbjct: 78 DGSGTIDFEEFLTMMTA 94 Score = 57.3 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 30/83 (36%), Gaps = 2/83 (2%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 + K QE + F + SG E K + G K + I ++ + Sbjct: 16 DQKKGRVGLTEEQKQEIREAFDLFDTD-GSGTIDAKELKVAMRALGFEPK-KEEIKKMIS 73 Query: 63 TFDTNKDGFVDFLEFIAAVNLIM 85 D + G +DF EF+ + M Sbjct: 74 EIDKDGSGTIDFEEFLTMMTAKM 96 >2ROB-A nrPDB Length = 70 Score = 70.1 bits (170), Expect = 7e-13, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 6/72 (8%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 E++LK FK++D D NG I +EL + +N + L+ EE + + + D++ D Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVM-----INLGEKLTDEE-VEQMIKEADLDGD 54 Query: 148 GELTLEEFINGM 159 G++ EEF+ M Sbjct: 55 GQVNYEEFVKMM 66 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 37/70 (52%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 A + + + + FD +++G++ E + + ++ +++++ K D DG+G ++ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 112 ELLDMFMAVQ 121 E + M M V+ Sbjct: 61 EFVKMMMTVR 70 >2RO9-A nrPDB Length = 69 Score = 69.7 bits (169), Expect = 9e-13, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 6/72 (8%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 E++LK F+++D D NG I EL + + + L+ EE ++ + + D++ D Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-----GEKLTDEE-VDEMIREADVDGD 54 Query: 148 GELTLEEFINGM 159 G++ EEF+ M Sbjct: 55 GQINYEEFVKVM 66 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 35/68 (51%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + + + + + FD +++GF+ E + + ++ ++++ + D DG+G I+ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 112 ELLDMFMA 119 E + + MA Sbjct: 61 EFVKVMMA 68 >2M5E-A nrPDB Length = 73 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 6/74 (8%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 ++ E++L FK++D DGNG I EL + + + L+ +E ++ + + DI+ Sbjct: 3 EQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-----GEKLTDDE-VDEMIREADID 56 Query: 146 NDGELTLEEFINGM 159 DG + EEF+ M Sbjct: 57 GDGHINYEEFVRMM 70 Score = 49.6 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 33/70 (47%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSID 109 Q + + + + + FD + +G + E + + ++ + ++ + D DG+G I+ Sbjct: 3 EQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHIN 62 Query: 110 KNELLDMFMA 119 E + M ++ Sbjct: 63 YEEFVRMMVS 72 >2N7L-C nrPDB Length = 141 Score = 68.5 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 34/86 (39%), Gaps = 1/86 (1%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 K+ E + F++ G + E ++ + G N + + ++ + Sbjct: 21 KAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTP-EELQEMIDEV 79 Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKME 90 D + G VDF EF+ + M++ E Sbjct: 80 DEDGSGTVDFDEFLVMMVRXMKDDSE 105 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 38/88 (43%), Gaps = 7/88 (7%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADG-NGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + A + E+ + + K F ++ +GSI EL + + Q +PEE Sbjct: 17 DDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-----GQNPTPEE 71 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + ++D + G + +EF+ M + Sbjct: 72 -LQEMIDEVDEDGSGTVDFDEFLVMMVR 98 Score = 40.0 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 1/79 (1%) Query: 49 LNQKANKHIDQVYNTFDTNK-DGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 L ++ ++ F DG + E + ++ Q ++L+ D DG+G+ Sbjct: 27 LTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 86 Query: 108 IDKNELLDMFMAVQALNGQ 126 +D +E L M + + + Sbjct: 87 VDFDEFLVMMVRXMKDDSE 105 >2LV7-A nrPDB Length = 100 Score = 67.7 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 6/66 (9%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++++ FK++D DGNG I K EL ++ + E + ++ ++D++ DG++ Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPN------EVELEVIIQRLDMDGDGQV 89 Query: 151 TLEEFI 156 EEF+ Sbjct: 90 DFEEFV 95 Score = 56.6 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 37/86 (43%) Query: 33 GLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK 92 G+ T+ + + + + I + + FD + +GF+ E A+ + E + Sbjct: 14 GIYTVPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVE 73 Query: 93 LKWYFKLYDADGNGSIDKNELLDMFM 118 L+ + D DG+G +D E + + Sbjct: 74 LEVIIQRLDMDGDGQVDFEEFVTLLG 99 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 +E ++ F + +G + E T + G ++ + D + DG VDF Sbjct: 35 LEEIREAFKVFDRD-GNGFISKQELGTAMRSLG-YMPNEVELEVIIQRLDMDGDGQVDFE 92 Query: 76 EFIAAV 81 EF+ + Sbjct: 93 EFVTLL 98 >2LC5-A nrPDB Length = 151 Score = 67.7 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 63/150 (42%), Gaps = 10/150 (6%) Query: 12 KAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF 71 A QE ++ F + + T E T++ G N + I ++ +D + G Sbjct: 9 TAEEQQEYKEAFQLFDKDNDN-KLTAEELGTVMRALGANPT-KQKISEIVKDYDKDNSGK 66 Query: 72 VDFLEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 D F+ + QE + +K F+++D + NG I +EL + + Sbjct: 67 FDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTLGEKLT----- 121 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMA 160 E+ ++ + +I + +G + +++F+ + Sbjct: 122 -EQEVDDLLKEIGV-EEGLINVDDFVKLIT 149 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 41/112 (36%), Gaps = 5/112 (4%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L + + + + FD + D + E + + +QK+ K YD D +G Sbjct: 8 LTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKF 67 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 D+ L + L Q + E I F D +G ++ E + + Sbjct: 68 DQETFLTIM-----LEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLT 114 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 ++ + +Q+ K F+L+D D + + EL + A+ A +Q +S + Sbjct: 5 KKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKIS------EIVKD 58 Query: 142 IDINNDGELTLEEFINGMA 160 D +N G+ E F+ M Sbjct: 59 YDKDNSGKFDQETFLTIML 77 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 43/105 (40%), Gaps = 2/105 (1%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 Q+ + + + SG F T++ G + + I + + FD K+G++ Sbjct: 48 TKQKISEIVKDYDKD-NSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISA 106 Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 E + + ++ EQ++ K + G I+ ++ + + + Sbjct: 107 SELKHVLTTLGEKLTEQEVDDLLKEIGVE-EGLINVDDFVKLITS 150 >5VLN-A nrPDB Length = 120 Score = 67.4 bits (163), Expect = 4e-12, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 36/91 (39%), Gaps = 1/91 (1%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 K+ E + F++ G + E ++ + G N + + ++ + Sbjct: 6 KAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTP-EELQEMIDEV 64 Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKW 95 D + G VDF EF+ + M++ + K K Sbjct: 65 DEDGSGTVDFDEFLVMMVRSMKDDSKGKFKR 95 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 44/106 (41%), Gaps = 8/106 (7%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADG-NGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + A + E+ + + K F ++ +GSI EL + + Q +PEE Sbjct: 2 DDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRML-----GQNPTPEE 56 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAKD-QDLLEIVYKSFDFSNV 178 + + ++D + G + +EF+ M + +D + +K V Sbjct: 57 -LQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKFKRPTLRRV 101 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 49 LNQKANKHIDQVYNTFDTNK-DGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 L ++ ++ F DG + E + ++ Q ++L+ D DG+G+ Sbjct: 12 LTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 71 Query: 108 IDKNELLDMFM 118 +D +E L M + Sbjct: 72 VDFDEFLVMMV 82 >2K7C-A nrPDB Length = 72 Score = 65.8 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++L+ F+ +D +G+G I +EL + + I + +D+N DG + Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHR-----DIEEIIRDVDLNGDGRV 61 Query: 151 TLEEFINGMAK 161 EEF+ M++ Sbjct: 62 DFEEFVRMMSR 72 Score = 46.9 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM-EQKLKWYFKLYDADGNGSIDKNEL 113 K + + FDTN DG + E A+ ++ ++ + ++ + D +G+G +D E Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEF 66 Query: 114 LDMFM 118 + M Sbjct: 67 VRMMS 71 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E +R F G + E + + +Q ++ I+++ D N DG VDF E Sbjct: 7 KELRDAFREFDTN-GDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 77 FIAAVNL 83 F+ ++ Sbjct: 66 FVRMMSR 72 >3IFK-A nrPDB Length = 90 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 11 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 68 Query: 78 IAAVNLIMQEK-MEQKLKWYFK 98 + + M++ E++++ F+ Sbjct: 69 LTMMARKMKDTDSEEEIREAFR 90 Score = 56.6 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + E+ + K F L+D DG+G+I EL + ++ + L + ++ Sbjct: 1 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINE 54 Query: 142 IDINNDGELTLEEFINGMAK 161 +D + +G + EF+ MA+ Sbjct: 55 VDADGNGTIDFPEFLTMMAR 74 Score = 53.1 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 34/84 (40%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L ++ + ++ FD + DG + E + + Q E +L+ DADGNG+I Sbjct: 4 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 63 Query: 109 DKNELLDMFMAVQALNGQQTLSPE 132 D E L M + E Sbjct: 64 DFPEFLTMMARKMKDTDSEEEIRE 87 >2B1U-A nrPDB Length = 71 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 6/72 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 + L+ F+ +D DG+G I +EL A+ G P+E ++ + + D++ DG + Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRR------AMAGLGQPLPQEELDAMIREADVDQDGRV 59 Query: 151 TLEEFINGMAKD 162 EEF +A++ Sbjct: 60 NYEEFARMLAQE 71 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 + + + FD + DG + E A+ + Q +++L + D D +G ++ E Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFA 65 Query: 115 DMFMA 119 M Sbjct: 66 RMLAQ 70 Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 ++ V +R F + G T+ E + + G + +D + D ++DG V++ Sbjct: 5 LEDLQVAFRAFDQD-GDGHITVDELRRAMAGLGQ-PLPQEELDAMIREADVDQDGRVNYE 62 Query: 76 EFIAAVN 82 EF + Sbjct: 63 EFARMLA 69 >5H7D-E nrPDB Length = 120 Score = 63.9 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 6/71 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q K F L+D DG+G+I EL + ++ + L + +++D + +G + Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDADGNGTI 109 Query: 151 TLEEFINGMAK 161 EF+ MA+ Sbjct: 110 DFPEFLTMMAR 120 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 8 AGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTN 67 A +K Q + F + G T E T++ G N + D + N D + Sbjct: 47 AEAKKLNQIQAFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDAD 104 Query: 68 KDGFVDFLEFIAAVNL 83 +G +DF EF+ + Sbjct: 105 GNGTIDFPEFLTMMAR 120 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 29/60 (48%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L M Sbjct: 60 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 119 >5COC-A nrPDB Length = 130 Score = 63.9 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 2/69 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 64 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 121 Query: 78 IAAVNLIMQ 86 + + M+ Sbjct: 122 LTMMARKMK 130 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 34/70 (48%), Gaps = 6/70 (8%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F L+D DG+G+I EL + ++ + L + +++D + +G + Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDADGNGTID 117 Query: 152 LEEFINGMAK 161 EF+ MA+ Sbjct: 118 FPEFLTMMAR 127 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 1/107 (0%) Query: 17 QETHVWYRTFMMEYPSGLQTL-HEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 +E + + + PS L E K L Q ++ + ++ FD + DG + Sbjct: 24 EEQRNAFIQSLKDDPSQSANLLAEAKCLNDAQAAAEECIAEFKEAFSLFDKDGDGTITTK 83 Query: 76 EFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 E + + Q E +L+ DADGNG+ID E L M Sbjct: 84 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK 130 >4WPX-A nrPDB Length = 177 Score = 63.9 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 55/157 (35%), Gaps = 19/157 (12%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD- 73 + F GL + EF+ +L G + + D + + D Sbjct: 24 QKTRISEAFELFDSN-KDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWPHDQ 82 Query: 74 -----FLEFIAAVNLIMQEKM------EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 + +F A + + +L+ F+L+D DG G I +++L + V Sbjct: 83 ECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQVGN 142 Query: 123 LNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 P+ I + + D N G + +EF+ M Sbjct: 143 NI------PDADIQAMIEEFDSNGKGGVDEDEFLRLM 173 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 39/103 (37%), Gaps = 9/103 (8%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 QE YR F L + L G + + + + FD + G + + Sbjct: 82 QECPPVYRQF---------NLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDD 132 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 + + ++ + +D++G G +D++E L + M+ Sbjct: 133 LRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDEDEFLRLMMS 175 Score = 33.5 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 12/120 (10%), Positives = 34/120 (28%), Gaps = 43/120 (35%) Query: 84 IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL-------------- 129 + ++ + ++ F+L+D++ +G + E + A+ +Q Sbjct: 19 KLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANW 78 Query: 130 -----------------------------SPEEFINLVFHKIDINNDGELTLEEFINGMA 160 P + + F D++ G +T ++ Sbjct: 79 PHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQ 138 >4GJF-A nrPDB Length = 89 Score = 63.5 bits (153), Expect = 6e-11, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 1/85 (1%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 K+ E + F+ G + E ++ + G N + + ++ + Sbjct: 6 KAAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTP-EELQEMIDEV 64 Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKM 89 D + G VDF EF+ + M++ Sbjct: 65 DEDGSGTVDFDEFLVMMVRCMKDDS 89 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 37/88 (42%), Gaps = 7/88 (7%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADG-NGSIDKNELLDMFMAVQALNGQQTLSPEE 133 + A + E+ + + K F ++ +G I EL + + Q +PEE Sbjct: 2 DDIYKAAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRML-----GQNPTPEE 56 Query: 134 FINLVFHKIDINNDGELTLEEFINGMAK 161 + + ++D + G + +EF+ M + Sbjct: 57 -LQEMIDEVDEDGSGTVDFDEFLVMMVR 83 Score = 36.5 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 49 LNQKANKHIDQVYNTF-DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 L ++ ++ F +DG + E + ++ Q ++L+ D DG+G+ Sbjct: 12 LTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 71 Query: 108 IDKNELLDMFM 118 +D +E L M + Sbjct: 72 VDFDEFLVMMV 82 >1JC2-A nrPDB Length = 76 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 6/74 (8%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 + K E++L F+++D + +G ID EL ++ A EE I + D N Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHV------IEEDIEDLMKDSDKN 58 Query: 146 NDGELTLEEFINGM 159 NDG + +EF+ M Sbjct: 59 NDGRIDFDEFLKMM 72 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 34/71 (47%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDK 110 K+ + + + FD N DGF+D E + + +E+ ++ K D + +G ID Sbjct: 6 GKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDF 65 Query: 111 NELLDMFMAVQ 121 +E L M VQ Sbjct: 66 DEFLKMMEGVQ 76 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 10 DQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 D K +E +R F G + E +L G + + I+ + D N D Sbjct: 3 DAKGKSEEELANCFRIFDKNAD-GFIDIEELGEILRATGEHV-IEEDIEDLMKDSDKNND 60 Query: 70 GFVDFLEFIAAV 81 G +DF EF+ + Sbjct: 61 GRIDFDEFLKMM 72 >2M7M-A nrPDB Length = 66 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 25/65 (38%), Positives = 35/65 (53%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ D N DG V + E A V+ K EQ L+ FK DADGNG ID+NE Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 117 FMAVQ 121 + ++Q Sbjct: 62 YGSIQ 66 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 29/62 (46%), Gaps = 6/62 (9%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 FK D +G+G++ E+ +A+ E+ + L+F ID + +GE+ EF Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKN------EQLLQLIFKSIDADGNGEIDQNEFA 59 Query: 157 NG 158 Sbjct: 60 KF 61 Score = 35.4 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 5/56 (8%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMA-----KDQDLLEIVYKSFDFSNVLRVICN 184 +F +ID+N DG ++ EE ++ K++ LL++++KS D + N Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQN 56 Score = 30.8 bits (68), Expect = 0.47, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 G + E K + + K + + ++ + D + +G +D EF Sbjct: 13 GDGAVSYEEVKAFVSKKRA-IKNEQLLQLIFKSIDADGNGEIDQNEF 58 >5XOP-A nrPDB Length = 66 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 21/64 (32%), Positives = 31/64 (48%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 + ++ D N DG V + E A V+ K EQ L+ FK D DG+G ID E Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Query: 117 FMAV 120 + ++ Sbjct: 62 YGSI 65 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 6/62 (9%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 FK D +G+G++ E+ +A+ E+ + L+F ID + DG + EEF Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKN------EQLLQLIFKSIDKDGDGFIDFEEFA 59 Query: 157 NG 158 Sbjct: 60 KF 61 Score = 36.2 bits (82), Expect = 0.011, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 G + E K + + K + + ++ + D + DGF+DF EF Sbjct: 13 GDGAVSYEEVKAFVSKKRA-IKNEQLLQLIFKSIDKDGDGFIDFEEF 58 Score = 34.2 bits (77), Expect = 0.041, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 27/46 (58%), Gaps = 5/46 (10%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMA-----KDQDLLEIVYKSFD 174 +F +ID+N DG ++ EE ++ K++ LL++++KS D Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSID 46 >1JUO-A nrPDB Length = 198 Score = 62.4 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 52/145 (35%), Gaps = 18/145 (12%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKH----IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 G E + L G+ + + D + G + F EF ++ Sbjct: 46 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 105 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 + F +D D +G++D EL + LSP + +N + + N Sbjct: 106 RQH------FISFDTDRSGTVDPQELQKALTTMGF-----RLSP-QAVNSIAKRYSTN-- 151 Query: 148 GELTLEEFINGMAKDQDLLEIVYKS 172 G++T +++I K + L + + Sbjct: 152 GKITFDDYIACCVKLRALTDSFRRR 176 Score = 40.0 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 50/142 (35%), Gaps = 23/142 (16%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 ET + + SG +EFK L + LN I +FDT++ G VD E Sbjct: 73 ETCRLMVSMLDRDMSGTMGFNEFKELWAV--LNGWRQHFI-----SFDTDRSGTVDPQEL 125 Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 A+ + Q + K Y NG I ++ + + L+ Sbjct: 126 QKALTTMGFRLSPQAVNSIAKRYST--NGKITFDDY------IACCVKLRALTDS----- 172 Query: 138 VFHKIDINNDGELTL--EEFIN 157 F + D G + ++FI Sbjct: 173 -FRRRDTAQQGVVNFPYDDFIQ 193 >5OTJ-D nrPDB Length = 110 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 7/85 (8%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 M ++ FK +D +G+G I +EL D + + + + + + +ID + DG Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALRTLGS-------TSADEVQRMMAEIDTDGDG 53 Query: 149 ELTLEEFINGMAKDQDLLEIVYKSF 173 + EFI+ + L++ V K F Sbjct: 54 FIDFNEFISFCNANPGLMKDVAKVF 78 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 54 NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 +++++ FDTN DG + E A+ + +++ D DG+G ID NE Sbjct: 2 ADDMERIFKRFDTNGDGKISLSELTDALRTLGS-TSADEVQRMMAEIDTDGDGFIDFNEF 60 Query: 114 LDMFMAVQALNGQ 126 + A L Sbjct: 61 ISFCNANPGLMKD 73 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 23 YRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAA 80 ++ F G +L E L G + + ++ DT+ DGF+DF EFI+ Sbjct: 9 FKRFDTN-GDGKISLSELTDALRTLG--STSADEVQRMMAEIDTDGDGFIDFNEFISF 63 >5MRA-A nrPDB Length = 167 Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 52/145 (35%), Gaps = 18/145 (12%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKH----IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 G E + L G+ + + D + G + F EF ++ Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 + F +D D +G++D EL + LSP + +N + + N Sbjct: 75 RQH------FISFDTDRSGTVDPQELQKALTTMGF-----RLSP-QAVNSIAKRYSTN-- 120 Query: 148 GELTLEEFINGMAKDQDLLEIVYKS 172 G++T +++I K + L + + Sbjct: 121 GKITFDDYIACCVKLRALTDSFRRR 145 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 50/142 (35%), Gaps = 23/142 (16%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 ET + + SG +EFK L + LN I +FDT++ G VD E Sbjct: 42 ETCRLMVSMLDRDMSGTMGFNEFKELWAV--LNGWRQHFI-----SFDTDRSGTVDPQEL 94 Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 A+ + Q + K Y NG I ++ + + L+ Sbjct: 95 QKALTTMGFRLSPQAVNSIAKRYST--NGKITFDDY------IACCVKLRALTDS----- 141 Query: 138 VFHKIDINNDGELTL--EEFIN 157 F + D G + ++FI Sbjct: 142 -FRRRDTAQQGVVNFPYDDFIQ 162 Score = 33.8 bits (76), Expect = 0.057, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 19/55 (34%), Gaps = 1/55 (1%) Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFING 158 +G ID +EL + G E L+ +D + G + EF Sbjct: 14 QDGQIDADELQRCLTQ-SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKEL 67 >1OZS-A nrPDB Length = 73 Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 6/76 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M+ K E++L F+++D + +G ID EL M A E+ I + D Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATG------ETITEDDIEELMKDGDK 54 Query: 145 NNDGELTLEEFINGMA 160 NNDG + +EF+ M Sbjct: 55 NNDGRIDYDEFLEFMK 70 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 33/71 (46%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDK 110 K+ + + ++ FD N DG++D E + + E ++ K D + +G ID Sbjct: 3 GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDY 62 Query: 111 NELLDMFMAVQ 121 +E L+ V+ Sbjct: 63 DEFLEFMKGVE 73 Score = 35.4 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 27/68 (39%), Gaps = 2/68 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F G L E K +L G I+++ D N DG +D+ Sbjct: 5 SEEELSDLFRMFDKNAD-GYIDLEELKIMLQATGETIT-EDDIEELMKDGDKNNDGRIDY 62 Query: 75 LEFIAAVN 82 EF+ + Sbjct: 63 DEFLEFMK 70 >3FWC-A nrPDB Length = 161 Score = 60.8 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 59/162 (36%), Gaps = 43/162 (26%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ---- 91 ++ L ++ + I + ++ FD N DGF+D+ E A+ + E ++ Sbjct: 4 NRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILD 63 Query: 92 ---------------------------------KLKWYFKLYDADGNGSIDKNELLDMFM 118 ++K F+L+D D G I L + Sbjct: 64 LIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAK 123 Query: 119 AVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 + +TL+ EE + + + D++ DGE+ EFI Sbjct: 124 EL-----GETLTDEE-LRAMIEEFDLDGDGEINENEFIAICT 159 >2I08-A nrPDB Length = 78 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ + K F LYD DG+G+I EL + ++ + L + +++D Sbjct: 4 LTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQD------MINEVDA 57 Query: 145 NNDGELTLEEFINGMAKD 162 + +G + EF+ MA+ Sbjct: 58 DGNGTIDFPEFLTMMARI 75 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + + + G T E T++ GLN + D + N D + +G +DF EF Sbjct: 11 EFKEAFSLYDKD-GDGTITTKELGTVMRSLGLNPTEAELQD-MINEVDADGNGTIDFPEF 68 Query: 78 IAAVNLIMQ 86 + + IM+ Sbjct: 69 LTMMARIMK 77 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L ++ + ++ +D + DG + E + + E +L+ DADGNG+I Sbjct: 4 LTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTI 63 Query: 109 DKNELLDMFMAVQAL 123 D E L M + Sbjct: 64 DFPEFLTMMARIMKY 78 >2RO8-A nrPDB Length = 79 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 30/74 (40%), Gaps = 2/74 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 E + F + G T E T++ G N + D + N D + +G +DF Sbjct: 8 QISEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDF 65 Query: 75 LEFIAAVNLIMQEK 88 EF+ + M++ Sbjct: 66 PEFLNLMARKMKDT 79 Score = 57.7 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + ++ + K F L+D DG+G I EL + ++ + L + ++ Sbjct: 1 ADQLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQD------MINE 54 Query: 142 IDINNDGELTLEEFINGMAK 161 +D + +G + EF+N MA+ Sbjct: 55 VDADGNGTIDFPEFLNLMAR 74 Score = 50.0 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 32/74 (43%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L + + ++ FD + DG + E + + Q E +L+ DADGNG+I Sbjct: 4 LTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 63 Query: 109 DKNELLDMFMAVQA 122 D E L++ Sbjct: 64 DFPEFLNLMARKMK 77 >2LVK-A nrPDB Length = 77 Score = 59.3 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 ++ FK +D +G+G I +EL D + + + + + + +ID + DG + Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGS-------TSADEVQRMMAEIDTDGDGFI 54 Query: 151 TLEEFINGMAKDQDLLEIVYKSF 173 EFI+ + L++ V K F Sbjct: 55 DFNEFISFCNANPGLMKDVAKVF 77 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 54 NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 +++++ FDTN DG + E A+ + +++ D DG+G ID NE Sbjct: 1 ADDMERIFKRFDTNGDGKISLSELTDALRTLGS-TSADEVQRMMAEIDTDGDGFIDFNEF 59 Query: 114 LDMFMAVQALNGQ 126 + A L Sbjct: 60 ISFCNANPGLMKD 72 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 23 YRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAA 80 ++ F G +L E L G + + ++ DT+ DGF+DF EFI+ Sbjct: 8 FKRFDTN-GDGKISLSELTDALRTLG--STSADEVQRMMAEIDTDGDGFIDFNEFISF 62 >2K2A-A nrPDB Length = 70 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 M+Q+L+ F+LYD +GNG I + + ++ + E ++ + +ID + G Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAEL------DETLSSEDLDAMIDEIDADGSG 54 Query: 149 ELTLEEFINGMA 160 + EEF+ M Sbjct: 55 TVDFEEFMGVMT 66 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 QE +R + E +G + + +L +++ +D + + D + G VDF Sbjct: 2 QQELREAFRLYDKE-GNGYISTDVMREILAELDETL-SSEDLDAMIDEIDADGSGTVDFE 59 Query: 76 EFIAAVN 82 EF+ + Sbjct: 60 EFMGVMT 66 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 27/64 (42%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 + + + + +D +G++ + + + + L DADG+G++D E + Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 62 Query: 115 DMFM 118 + Sbjct: 63 GVMT 66 >2BL0-B nrPDB Length = 145 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 50/142 (35%), Gaps = 41/142 (28%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLK------------------ 94 + I + + FD + DG V E +A+ + + +L Sbjct: 3 SADQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATFKT 62 Query: 95 -----------------WYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 F+ D +GNG+I + EL + LN L+ E + Sbjct: 63 VYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLL-----LNLGDALTSSE-VEE 116 Query: 138 VFHKIDINNDGELTLEEFINGM 159 + ++ ++ DG + E F++ + Sbjct: 117 LMKEVSVSGDGAINYESFVDML 138 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 32/98 (32%), Gaps = 6/98 (6%) Query: 32 SGLQTLHEF-----KTLLGLQGLNQKA-NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 G EF KT+ +K + + D +G + E + + Sbjct: 47 KGQLNAKEFDLATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLG 106 Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL 123 +++ K G+G+I+ +DM + L Sbjct: 107 DALTSSEVEELMKEVSVSGDGAINYESFVDMLVTGYPL 144 >1F55-A nrPDB Length = 77 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 6/80 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + + E+ + K F L+D D NGSI +EL + ++ E +N + ++ Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLG------LSPSEAEVNDLMNE 54 Query: 142 IDINNDGELTLEEFINGMAK 161 ID++ + ++ EF+ M++ Sbjct: 55 IDVDGNHQIEFSEFLALMSR 74 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + +G + E T++ GL+ + ++ + N D + + ++F EF Sbjct: 11 EFKEAFALFDKD-NNGSISSSELATVMRSLGLSP-SEAEVNDLMNEIDVDGNHQIEFSEF 68 Query: 78 IAAVNLIMQ 86 +A ++ ++ Sbjct: 69 LALMSRQLK 77 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 27/71 (38%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 L ++ + + FD + +G + E + + E ++ D DGN Sbjct: 3 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQ 62 Query: 108 IDKNELLDMFM 118 I+ +E L + Sbjct: 63 IEFSEFLALMS 73 >5JOJ-A nrPDB Length = 97 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 10/95 (10%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L+ F D DGNG I NEL D+F A A E + D++ DG ++ Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKA--ACLPLPGYRVREITENLMATGDLDQDGRIS 70 Query: 152 LEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGK 186 +EFI KS D + R N K Sbjct: 71 FDEFIKIFHGL--------KSTDVAKTFRKAINKK 97 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE----FIAAVNLIMQEKMEQKLKWYFKL 99 + ++ + + + + DT+ +G++ F E F AA + ++ + + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60 Query: 100 YDADGNGSIDKNELLDMFMAVQA 122 D D +G I +E + +F +++ Sbjct: 61 GDLDQDGRISFDEFIKIFHGLKS 83 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 30/84 (35%), Gaps = 4/84 (4%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLG---LQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 E + + +G + +E L L + + + + T D ++DG + F Sbjct: 13 ELREAFAKVDTD-GNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 75 LEFIAAVNLIMQEKMEQKLKWYFK 98 EFI + + + + + Sbjct: 72 DEFIKIFHGLKSTDVAKTFRKAIN 95 >4Q57-A nrPDB Length = 65 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + K F L+D DG+G+I EL + ++ + L + +++D + +G + Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD------MINEVDADGNGTID 56 Query: 152 LEEFINGM 159 EF+ M Sbjct: 57 FPEFLTMM 64 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G T E T++ G N + D + N D + +G +DF EF Sbjct: 3 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 60 Query: 78 IAAVN 82 + + Sbjct: 61 LTMMA 65 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 29/64 (45%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 + ++ FD + DG + E + + Q E +L+ DADGNG+ID E L Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 61 Query: 115 DMFM 118 M Sbjct: 62 TMMA 65 >5JOL-A nrPDB Length = 82 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L+ F D DGNG I NEL D+F A A E + D++ DG ++ Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKA--ACLPLPGYRVREITENLMATGDLDQDGRIS 70 Query: 152 LEEFING 158 +EFI Sbjct: 71 FDEFIKI 77 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 36/82 (43%), Gaps = 4/82 (4%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE----FIAAVNLIMQEKMEQKLKWYFKL 99 + ++ + + + + DT+ +G++ F E F AA + ++ + + Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60 Query: 100 YDADGNGSIDKNELLDMFMAVQ 121 D D +G I +E + +F ++ Sbjct: 61 GDLDQDGRISFDEFIKIFHGLK 82 >2M97-A nrPDB Length = 69 Score = 58.1 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 6/71 (8%) Query: 89 MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 148 E++L F+++D DGNG ID+ E D+ +E ++ +F D + +G Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLT------DEDVDEIFGDSDTDKNG 54 Query: 149 ELTLEEFINGM 159 + +EF+ M Sbjct: 55 RIDFDEFLKMM 65 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 35/69 (50%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 + + + + + FD + +GF+D EF + L ++ ++ + F D D NG ID +E Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 113 LLDMFMAVQ 121 L M VQ Sbjct: 61 FLKMMENVQ 69 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E +R F + +G EF ++ L G ++ +D+++ DT+K+G +DF Sbjct: 1 SEEELSECFRIFDKD-GNGFIDREEFGDIIRLTGEQLT-DEDVDEIFGDSDTDKNGRIDF 58 Query: 75 LEFIAAV 81 EF+ + Sbjct: 59 DEFLKMM 65 >4P5W-A nrPDB Length = 411 Score = 58.1 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 49/120 (40%), Gaps = 5/120 (4%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDAD 103 L + G +Q K ++ + D KDG + F EF+A +++ + F+L+D Sbjct: 67 LNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAP--DALFMVAFQLFDKA 124 Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 G G + ++ +F EF+ L F K + LT EF + + Q Sbjct: 125 GKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRH---LTYAEFTQFLLEIQ 181 >1GJY-A nrPDB Length = 167 Score = 58.1 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 50/145 (34%), Gaps = 18/145 (12%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKH----IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 G E + L G+ + + D + G + F EF ++ Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 + F +D+D +G++D EL + QT +N + + Sbjct: 75 RQH------FISFDSDRSGTVDPQELQKALTTMGFRLNPQT------VNSIAKRYST--S 120 Query: 148 GELTLEEFINGMAKDQDLLEIVYKS 172 G++T +++I K + L + + Sbjct: 121 GKITFDDYIACCVKLRALTDSFRRR 145 Score = 33.5 bits (75), Expect = 0.073, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 19/55 (34%), Gaps = 1/55 (1%) Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFING 158 +G ID +EL + G E L+ +D + G + EF Sbjct: 14 QDGQIDADELQRCLTQ-SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKEL 67 >2KSZ-A nrPDB Length = 76 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 I+ E+ K F L+D DG+G I EL + ++ EE + + + Sbjct: 1 ADILSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPT------EEELQDMISE 54 Query: 142 IDINNDGELTLEEFINGMAK 161 +D + +G + +EF++ MAK Sbjct: 55 VDADGNGTIEFDEFLSLMAK 74 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 34/70 (48%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L+++ + + FD + DG + E + + Q E++L+ DADGNG+I Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 109 DKNELLDMFM 118 + +E L + Sbjct: 64 EFDEFLSLMA 73 Score = 46.9 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 + + F + G T+ E T++ N + D + + D + +G ++F EF Sbjct: 11 DFKEAFGLFDKD-GDGCITVEELATVIRSLDQNPTEEELQD-MISEVDADGNGTIEFDEF 68 Query: 78 IAAVNLI 84 ++ + Sbjct: 69 LSLMAKK 75 >1YX7-A nrPDB Length = 83 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 36/72 (50%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M K++ +L+ FK DA+G+G + EL + + A +E + D Sbjct: 1 MACKVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADK 60 Query: 145 NNDGELTLEEFI 156 N+DG+++ EEF+ Sbjct: 61 NSDGKISKEEFL 72 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAV------NLIMQEKMEQKLKWYFKLYDADGN 105 K ++ + D N DG+V LE + + ++K+++ K+ D + + Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD 63 Query: 106 GSIDKNELLD 115 G I K E L+ Sbjct: 64 GKISKEEFLN 73 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 24/70 (34%), Gaps = 6/70 (8%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQ-----KANKHIDQVYNTFDTNKDG 70 E ++ + G T E +T + + K + ++ D N DG Sbjct: 6 KAELEAAFKK-LDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDG 64 Query: 71 FVDFLEFIAA 80 + EF+ A Sbjct: 65 KISKEEFLNA 74 >1Y1X-A nrPDB Length = 191 Score = 57.0 bits (136), Expect = 6e-09, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 49/141 (34%), Gaps = 25/141 (17%) Query: 43 LLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN----LIMQEKMEQKLKWYFK 98 + + N+ + + + DT+ G + E AA++ E+ L Sbjct: 15 VYAPSARHMNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLH---- 70 Query: 99 LYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFIN- 157 +YD + +G I +E D+ + ++ F K D + DG L E Sbjct: 71 MYDKNHSGEITFDEFKDLHHFILSMREG------------FRKRDSSGDGRLDSNEVRAA 118 Query: 158 ----GMAKDQDLLEIVYKSFD 174 G + + + + FD Sbjct: 119 LLSSGYQVSEQTFQALMRKFD 139 Score = 36.9 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 50/129 (38%), Gaps = 21/129 (16%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 SG T EFK L + + + D++ DG +D E AA+ + EQ Sbjct: 77 SGEITFDEFKDLHHFI-------LSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQ 129 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL- 150 + + +D GS+ ++ +++ + V + VF D G++ Sbjct: 130 TFQALMRKFDRQRRGSLGFDDYVELSIFV------------CRVRNVFAFYDRERTGQVT 177 Query: 151 -TLEEFING 158 T + FI G Sbjct: 178 FTFDTFIGG 186 >4P5X-A nrPDB Length = 315 Score = 56.6 bits (135), Expect = 8e-09, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 50/131 (38%), Gaps = 6/131 (4%) Query: 34 LQTLHEF-KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK 92 T +F + LGL K + + D KDG + + EF+A +++ + Sbjct: 37 YMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAP--DSM 94 Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 F+L+D GNG + + ++F + EFI L F N L Sbjct: 95 FIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHF---GHNRKKHLNY 151 Query: 153 EEFINGMAKDQ 163 EF + + Q Sbjct: 152 TEFTQFLQELQ 162 Score = 35.0 bits (79), Expect = 0.023, Method: Composition-based stats. Identities = 31/194 (15%), Positives = 62/194 (31%), Gaps = 40/194 (20%) Query: 19 THVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQ--KANKHIDQVYNTFDTNKDGFVDFLE 76 V ++ F +G T K + G ++ N + + F N+ +++ E Sbjct: 95 FIVAFQLFDKS-GNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTE 153 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ--------- 127 F + QE + + F L D +G I + D+ + +++ Sbjct: 154 FTQFL----QELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSA 209 Query: 128 -------------------TLSPEEFINLVFH-KIDINNDGELTLEEFINGM----AKDQ 163 L+ E + ++ D E+T EEF Sbjct: 210 AGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTP 269 Query: 164 DLLEIVYKSFDFSN 177 ++I+Y+ D N Sbjct: 270 LEIDILYQLADLYN 283 >5Z1Q-A nrPDB Length = 95 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 39/74 (52%) Query: 46 LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGN 105 Q L+++ + I + ++ FDTNK G +D+ E A+ + + + ++ YD +GN Sbjct: 18 RQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGN 77 Query: 106 GSIDKNELLDMFMA 119 G I ++ LD+ Sbjct: 78 GYIGFDDFLDIMTE 91 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 6/76 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ +Q++K F L+D + GSID +EL A+ G PE I + ++ D Sbjct: 21 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRAL----GFDVKKPE--ILELMNEYDR 74 Query: 145 NNDGELTLEEFINGMA 160 +G + ++F++ M Sbjct: 75 EGNGYIGFDDFLDIMT 90 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 33/82 (40%), Gaps = 2/82 (2%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTF 64 K + + QE + F +G HE K + G + K I ++ N + Sbjct: 15 KRVRQELSEEQKQEIKEAFDLFDTN-KTGSIDYHELKVAMRALGFDVK-KPEILELMNEY 72 Query: 65 DTNKDGFVDFLEFIAAVNLIMQ 86 D +G++ F +F+ + ++ Sbjct: 73 DREGNGYIGFDDFLDIMTEKIK 94 >1ZMZ-A nrPDB Length = 98 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 34/77 (44%) Query: 46 LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGN 105 L ++ + I + ++ FD + G +D E A+ + E ++++K D +G Sbjct: 22 KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGT 81 Query: 106 GSIDKNELLDMFMAVQA 122 G ++ + L + + Sbjct: 82 GKMNFGDFLTVMTQKMS 98 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 6/76 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ +Q+++ F L+DADG G+ID EL A+ + E I + +ID Sbjct: 25 LTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK------EEIKKMISEIDK 78 Query: 145 NNDGELTLEEFINGMA 160 G++ +F+ M Sbjct: 79 EGTGKMNFGDFLTVMT 94 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + F + +G + E K + G K + I ++ + D G ++F Sbjct: 29 QKQEIREAFDLFDAD-GTGTIDVKELKVAMRALGFEPK-KEEIKKMISEIDKEGTGKMNF 86 Query: 75 LEFIAAVNLIMQ 86 +F+ + M Sbjct: 87 GDFLTVMTQKMS 98 >1C7W-A nrPDB Length = 81 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 46/82 (56%), Gaps = 5/82 (6%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 ++ E+++ FK++DA+G+G ID +E + V G++ L+ E + + D + Sbjct: 3 RQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKV----GEEPLTDAE-VEEAMKEADED 57 Query: 146 NDGELTLEEFINGMAKDQDLLE 167 +G + + EF++ + K ++ L+ Sbjct: 58 GNGVIDIPEFMDLIKKSKNALK 79 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM-EQKLKWYFKLYDADGNGSID 109 Q + I + + FD N DG +DF EF + + +E + + +++ K D DGNG ID Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVID 63 Query: 110 KNELLDMFM 118 E +D+ Sbjct: 64 IPEFMDLIK 72 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 28/75 (37%), Gaps = 1/75 (1%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 +E ++ F G+ EFK ++ G + +++ D + +G +D Sbjct: 7 EEEILRAFKVFDAN-GDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIP 65 Query: 76 EFIAAVNLIMQEKME 90 EF+ + E Sbjct: 66 EFMDLIKKSKNALKE 80 >1TNP-A nrPDB Length = 90 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G + E T++ + G N + +D + D + G +DF EF Sbjct: 21 EFKAAFDMFDAD-GGGDISTKELGTVMRMLGQNPT-KEELDAIIEEVDEDGSGTIDFEEF 78 Query: 78 IAAVNLIMQEK 88 + + M+E Sbjct: 79 LVMMVRQMKED 89 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 + E+M + K F ++DADG G I EL + + ++ L + + Sbjct: 10 ARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEEL------DAIIE 63 Query: 141 KIDINNDGELTLEEFINGMAK 161 ++D + G + EEF+ M + Sbjct: 64 EVDEDGSGTIDFEEFLVMMVR 84 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 35/84 (41%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLY 100 + L+++ ++ FD + G + E + ++ Q +++L + Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEV 65 Query: 101 DADGNGSIDKNELLDMFMAVQALN 124 D DG+G+ID E L M + + Sbjct: 66 DEDGSGTIDFEEFLVMMVRQMKED 89 >2G9B-A nrPDB Length = 263 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 16/132 (12%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGL-------NQKANKHIDQVYNT 63 Q+ +E +R + ++ SG E K L + K ++ D + Sbjct: 97 QQLKSCEEFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 155 Query: 64 FDTNKDGFVDFLEFIAAVNLIMQEKME--------QKLKWYFKLYDADGNGSIDKNELLD 115 FD+N DG ++ E + + ++ ++ F+LYD DGNG ID+NEL Sbjct: 156 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 215 Query: 116 MFMAVQALNGQQ 127 + + N Q+ Sbjct: 216 LLKDLCEKNKQE 227 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 55/152 (36%), Gaps = 16/152 (10%) Query: 31 PSGLQTLHEFKTLL-----GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV---- 81 SG E + L+ + + + + + + DG + +E + Sbjct: 29 GSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEE 88 Query: 82 -----NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV--QALNGQQTLSPEEF 134 Q K ++ ++ YD D +G I+ EL + + +A E+ Sbjct: 89 NFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 148 Query: 135 INLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +L+ D NNDG+L L E + ++ L Sbjct: 149 TDLMLKLFDSNNDGKLELTEMARLLPVQENFL 180 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 25/149 (16%), Positives = 57/149 (38%), Gaps = 20/149 (13%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE-------- 87 T F L K+ + + + +DT+ GF++ E + ++++ Sbjct: 86 TEENFLLLFRC--QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 143 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMF----MAVQALNGQQTLSPEEFINLVFHKID 143 K+ + KL+D++ +G ++ E+ + + G + E N F D Sbjct: 144 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKE--FNKAFELYD 201 Query: 144 INNDGELTLEE----FINGMAKDQDLLEI 168 + +G + E + K++ L+I Sbjct: 202 QDGNGYIDENELDALLKDLCEKNKQELDI 230 Score = 35.4 bits (80), Expect = 0.020, Method: Composition-based stats. Identities = 13/101 (12%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Query: 100 YDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 +DADG+G ++ EL ++ + + L + + +DG++ + E + + Sbjct: 25 FDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 84 Query: 160 AKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDK 200 +++ L ++++ + + ++ D + ++ Sbjct: 85 PTEENFL-LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 124 >1TRF-A nrPDB Length = 76 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 84 IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKID 143 + E+M + K F ++DADG G I EL + + ++ L + + ++D Sbjct: 2 FLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEEL------DAIIEEVD 55 Query: 144 INNDGELTLEEFINGMAK 161 + G + EEF+ M + Sbjct: 56 EDGSGTIDFEEFLVMMVR 73 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 29/69 (42%), Gaps = 2/69 (2%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E + F + G + E T++ + G N + +D + D + G +DF EF Sbjct: 10 EFKAAFDMFDAD-GGGDISTKELGTVMRMLGQNPT-KEELDAIIEEVDEDGSGTIDFEEF 67 Query: 78 IAAVNLIMQ 86 + + M+ Sbjct: 68 LVMMVRQMK 76 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 33/71 (46%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 L+++ ++ FD + G + E + ++ Q +++L + D DG+G+ Sbjct: 2 FLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGT 61 Query: 108 IDKNELLDMFM 118 ID E L M + Sbjct: 62 IDFEEFLVMMV 72 >1M39-A nrPDB Length = 89 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 7/90 (7%) Query: 73 DFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 +F +F+ + M EK ++++ FKL+D D G I L + + + L+ Sbjct: 2 NFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-----GENLTD 56 Query: 132 EEFINLVFHKIDINNDGELTLEEFINGMAK 161 EE + + + D + DGE++ +EF+ M K Sbjct: 57 EE-LQEMIDEADRDGDGEVSEQEFLRIMKK 85 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 35/80 (43%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 +F T++ + + + I + + FD ++ G + F + + +++L+ Sbjct: 5 DFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMID 64 Query: 99 LYDADGNGSIDKNELLDMFM 118 D DG+G + + E L + Sbjct: 65 EADRDGDGEVSEQEFLRIMK 84 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 + +E ++ F + +G + K + G N ++ + ++ + D + DG Sbjct: 15 SEKDTKEEILKAFKLF-DDDETGKISFKNLKRVAKELGENLT-DEELQEMIDEADRDGDG 72 Query: 71 FVDFLEFIAAVNLIM 85 V EF+ + Sbjct: 73 EVSEQEFLRIMKKTS 87 >3MSE-B nrPDB Length = 180 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 54/139 (38%), Gaps = 24/139 (17%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +G + E T+L G+ + I+++ D N G + + EF+A + K + Sbjct: 53 NGSLSHREIYTVLASVGIKKW---DINRILQALDINDRGNITYTEFMAG---CYRWKNIE 106 Query: 92 K--LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDG- 148 LK F D D +G I K++++ + + I+ F + G Sbjct: 107 STFLKAAFNKIDKDEDGYISKSDIVSLV--------HDKVLDNNDIDNFFLSVHSIKKGI 158 Query: 149 -------ELTLEEFINGMA 160 +++ +EF + M Sbjct: 159 PREHIINKISFQEFKDYML 177 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 48/106 (45%), Gaps = 9/106 (8%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 K+I++++ DTN +G + E + + +K + + + D + G+I E Sbjct: 39 KYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWD--INRILQALDINDRGNITYTEF- 95 Query: 115 DMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 M + N + T F+ F+KID + DG ++ + ++ + Sbjct: 96 -MAGCYRWKNIEST-----FLKAAFNKIDKDEDGYISKSDIVSLVH 135 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 36/86 (41%), Gaps = 12/86 (13%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 + F D + NGS+ E+ + +V IN + +DIN+ G +T Sbjct: 41 INELFYKLDTNHNGSLSHREIYTVLASVGIKKWD--------INRILQALDINDRGNITY 92 Query: 153 EEFINGMAKDQDL----LEIVYKSFD 174 EF+ G + +++ L+ + D Sbjct: 93 TEFMAGCYRWKNIESTFLKAAFNKID 118 >2OPO-A nrPDB Length = 86 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 44/80 (55%), Gaps = 7/80 (8%) Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 + FK +D +G+G I +EL D AL +++P+E + + +ID + DG ++ + Sbjct: 14 ERIFKRFDTNGDGKISSSELGD------ALKTLGSVTPDE-VRRMMAEIDTDGDGFISFD 66 Query: 154 EFINGMAKDQDLLEIVYKSF 173 EF + ++ L++ V K F Sbjct: 67 EFTDFARANRGLVKDVSKIF 86 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 ++++ FDTN DG + E A+ + ++ ++ D DG+G I +E D Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGSVTPDE-VRRMMAEIDTDGDGFISFDEFTDFA 72 Query: 118 MAVQALNGQ 126 A + L Sbjct: 73 RANRGLVKD 81 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 21/55 (38%), Gaps = 3/55 (5%) Query: 23 YRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 ++ F G + E L G + ++ DT+ DGF+ F EF Sbjct: 17 FKRFDTN-GDGKISSSELGDALKTLG--SVTPDEVRRMMAEIDTDGDGFISFDEF 68 >5ZGM-A nrPDB Length = 110 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 6/104 (5%) Query: 57 IDQVYNTFDTNKD-GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D + KD G D+ F V L + K E ++K F++ D D +G I++ EL Sbjct: 9 ADDINKAVSAFKDPGTFDYKRFFQLVGL--KGKSEAQVKEVFEILDKDQSGFIEEEELKS 66 Query: 116 MFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 + + + + D ++DG++ +EF + Sbjct: 67 VLK---GFSAHGRDLSDTETKALLAAGDSDHDGKIGADEFAKMV 107 Score = 46.2 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV---NLIMQEKMEQKLKW 95 ++K L GL K+ + +V+ D ++ GF++ E + + + ++ + + K Sbjct: 26 DYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKA 85 Query: 96 YFKLYDADGNGSIDKNELLDMFMA 119 D+D +G I +E M Sbjct: 86 LLAAGDSDHDGKIGADEFAKMVAQ 109 Score = 31.2 bits (69), Expect = 0.38, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 21/53 (39%), Gaps = 2/53 (3%) Query: 32 SGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 SG E K++L + + ++ + D++ DG + EF V Sbjct: 56 SGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAGDSDHDGKIGADEFAKMVA 108 >1W7I-B nrPDB Length = 151 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 55/147 (37%), Gaps = 12/147 (8%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN-TFDTNKDGFVD 73 +E + F G + ++ G N + + + N D K VD Sbjct: 8 QLEEFKEAFELFDR-VGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVD 66 Query: 74 FLEFIAAVNLIMQEKME---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 F F+ + + + + + + F+++D +GNG + EL + + + ++ Sbjct: 67 FETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTL-----GEKMT 121 Query: 131 PEEFINLVFHKIDINNDGELTLEEFIN 157 EE ++ D N G + E F+ Sbjct: 122 EEEVETVLAGHEDSN--GCINYEAFLK 146 >1GGW-A nrPDB Length = 140 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 49/135 (36%), Gaps = 15/135 (11%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 +G LL G N + ++ VD +F+ +N M Sbjct: 18 GTGRIPKTSIGDLLRACGQNPTLAE-----ITEIESTLPAEVDMEQFLQVLNRPNGFDMP 72 Query: 91 ---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 ++ F+++D D G I EL + ++ + LS EE + + + + D Sbjct: 73 GDPEEFVKGFQVFDKDATGMIGVGELRYVLTSL-----GEKLSNEEM-DELLKGVPV-KD 125 Query: 148 GELTLEEFINGMAKD 162 G + +F+ + + Sbjct: 126 GMVNYHDFVQMILAN 140 Score = 26.5 bits (57), Expect = 9.3, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 27/76 (35%), Gaps = 9/76 (11%) Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS-------PEEFINLVFHKIDINN 146 K F L+D G G I K + D+ A ++ E + ++ N Sbjct: 8 KQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEITEIESTLPAEVDMEQFLQVLNRPN 67 Query: 147 DGEL--TLEEFINGMA 160 ++ EEF+ G Sbjct: 68 GFDMPGDPEEFVKGFQ 83 >2M8U-A nrPDB Length = 77 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 34/78 (43%), Gaps = 6/78 (7%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + + + ++ FK++D DGNG + + L + + + P + I + ++ Sbjct: 2 SHMNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMM------PADEIEEMIYE 55 Query: 142 IDINNDGELTLEEFINGM 159 D N G + E F+ + Sbjct: 56 ADPQNSGYVQYETFVGML 73 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 8/65 (12%), Positives = 22/65 (33%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNE 112 + + + FD + +G+V +N + +++ D +G + Sbjct: 9 TKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYET 68 Query: 113 LLDMF 117 + M Sbjct: 69 FVGML 73 >1F4Q-A nrPDB Length = 165 Score = 53.5 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 48/145 (33%), Gaps = 18/145 (12%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHI----DQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 G E + L G+N + + D + G + F F + Sbjct: 13 DGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAW 72 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 K F D DG+G+++ +EL + QTL+ + + N Sbjct: 73 K------ENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLT------TIVKRYSKN-- 118 Query: 148 GELTLEEFINGMAKDQDLLEIVYKS 172 G + ++++ K + L + K Sbjct: 119 GRIFFDDYVACCVKLRALTDFFKKR 143 Score = 32.7 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 21/55 (38%), Gaps = 1/55 (1%) Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFING 158 +G +D EL +NG + E ++ +D ++ G++ F Sbjct: 12 QDGEVDAEELQRCLTQ-SGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKEL 65 >2JOJ-A nrPDB Length = 77 Score = 53.5 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 38/71 (53%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L+++ + I + ++ FDTNK G +D+ E A+ + + + ++ YD +GNG I Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYI 60 Query: 109 DKNELLDMFMA 119 ++ LD+ Sbjct: 61 GFDDFLDIMTE 71 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 6/76 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + E+ +Q++K F L+D + GSID +EL A+ + + + ++ D Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEIL------ELMNEYDR 54 Query: 145 NNDGELTLEEFINGMA 160 +G + ++F++ M Sbjct: 55 EGNGYIGFDDFLDIMT 70 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + F +G HE K + G + K I ++ N +D +G++ F Sbjct: 5 QKQEIKEAFDLFDTN-KTGSIDYHELKVAMRALGFDVK-KPEILELMNEYDREGNGYIGF 62 Query: 75 LEFIAAVNLIMQ 86 +F+ + ++ Sbjct: 63 DDFLDIMTEKIK 74 >1H4B-A nrPDB Length = 84 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 7/87 (8%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 146 + + + + FK +DA+G+G I EL + + ++ + + + +ID + Sbjct: 5 PQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDE-------VKHMMAEIDTDG 57 Query: 147 DGELTLEEFINGMAKDQDLLEIVYKSF 173 DG ++ +EF + ++ LL+ V K F Sbjct: 58 DGFISFQEFTDFGRANRGLLKDVAKIF 84 Score = 46.6 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSID 109 + + ++++ FD N DG + E A+ + ++ +K D DG+G I Sbjct: 4 HPQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDE-VKHMMAEIDTDGDGFIS 62 Query: 110 KNELLDMFMAVQAL 123 E D A + L Sbjct: 63 FQEFTDFGRANRGL 76 Score = 37.3 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 22/69 (31%), Gaps = 3/69 (4%) Query: 9 GDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 D E ++ F G + E L G + + DT+ Sbjct: 1 ADDHPQDKAERERIFKRFDAN-GDGKISAAELGEALKTLG--SITPDEVKHMMAEIDTDG 57 Query: 69 DGFVDFLEF 77 DGF+ F EF Sbjct: 58 DGFISFQEF 66 >2Q4U-A nrPDB Length = 272 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 55/173 (31%), Gaps = 27/173 (15%) Query: 8 AGDQKAVPTQETHVWYRTFMMEY-PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDT 66 A D + +E ++R + + P T + + + +D Sbjct: 22 ADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSF-------------MSAYDA 68 Query: 67 NKDGFVDFLE-----------FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 DG + E F+ + ++ YDAD +G I EL + Sbjct: 69 TFDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKN 128 Query: 116 MFMA--VQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +Q +E+ + + D N DG L L + +A ++ L Sbjct: 129 FLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFL 181 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 51/144 (35%), Gaps = 21/144 (14%) Query: 32 SGLQTLHEFKTLLGLQGLNQKAN-------KHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 SG + E K L L K ++ D + FD NKDG +D + + L Sbjct: 118 SGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQ 177 Query: 85 ------------MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN--GQQTLS 130 Q + ++ + F YD G+++ E+ + L Sbjct: 178 ENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDMMELVRPSISGGD 237 Query: 131 PEEFINLVFHKIDINNDGELTLEE 154 ++F + D+N DG++ E Sbjct: 238 LDKFRECLLTHCDMNKDGKIQKSE 261 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 100 YDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV----FHKIDINNDGELTLEEF 155 +DAD NG I+ EL D F + + +E + + D DG L +EE Sbjct: 20 FDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEEL 79 Query: 156 INGMAKDQDLLEIVYKS 172 N + ++ ++++ Sbjct: 80 ANMILPQEENFLLIFRR 96 Score = 40.0 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 19/149 (12%), Positives = 54/149 (36%), Gaps = 23/149 (15%) Query: 11 QKAVPTQETHVWYRTFMMEYP---SGLQTLHE-----------FKTLLGLQGLNQKANKH 56 + + + ++FM Y G + E F + + + + Sbjct: 47 KDKITDERVQQIKKSFMSAYDATFDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEF 106 Query: 57 IDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEK-----MEQKLKWYFKLYDADGNGSI 108 + +++ +D + G++ E F+ + L ++K +++ K++D + +G + Sbjct: 107 M-KIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRL 165 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINL 137 D N+L + + Q + + Sbjct: 166 DLNDLARILALQENFLLQFKMDASSQVER 194 >5XND-A nrPDB Length = 114 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 G D +F A L K ++K F + D D +G I++ EL +A G + L Sbjct: 28 GSFDHKKFFKACGL--SGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKA--GARAL 83 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFINGMA 160 S E D + DG++ ++EF + Sbjct: 84 SDAE-TKAFLKAGDSDGDGKIGIDEFAAMIK 113 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 3/81 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWYF 97 K GL+ K+ + + + D +K GF++ E F+ + + + K + Sbjct: 33 KKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFL 92 Query: 98 KLYDADGNGSIDKNELLDMFM 118 K D+DG+G I +E M Sbjct: 93 KAGDSDGDGKIGIDEFAAMIK 113 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 22/70 (31%), Gaps = 3/70 (4%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKA--NKHIDQVYNTFDTNKDGFV 72 T E + + SG E K L +A + D++ DG + Sbjct: 45 STDEVKKAFAIIDQD-KSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKI 103 Query: 73 DFLEFIAAVN 82 EF A + Sbjct: 104 GIDEFAAMIK 113 >5PAL-A nrPDB Length = 109 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 43/104 (41%), Gaps = 6/104 (5%) Query: 57 IDQVYNTFDTNKD-GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D + KD G D+ F V L + K + ++K F++ D D +G I++ EL Sbjct: 8 ADDINKAISAFKDPGTFDYKRFFHLVGL--KGKTDAQVKEVFEILDKDQSGFIEEEELKG 65 Query: 116 MFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 + + + + D ++DG++ +EF + Sbjct: 66 VLK---GFSAHGRDLNDTETKALLAAGDSDHDGKIGADEFAKMV 106 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV---NLIMQEKMEQKLKW 95 ++K L GL K + + +V+ D ++ GF++ E + + ++ + + K Sbjct: 25 DYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKA 84 Query: 96 YFKLYDADGNGSIDKNELLDMFMA 119 D+D +G I +E M Sbjct: 85 LLAAGDSDHDGKIGADEFAKMVAQ 108 >1JF0-A nrPDB Length = 195 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 27/58 (46%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D V++ FD + G + E+ A + E+ + F+ D D +G +D +E+ Sbjct: 116 DAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTR 173 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 48/145 (33%), Gaps = 28/145 (19%) Query: 31 PSGLQTLHEFKT-----LLGLQGLNQKANKHIDQVYNTFDTNKDGFV-----DFLEFIAA 80 +G TL E + + G + F G F EF+ Sbjct: 33 GNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAF-FRGCGLEYGKETKFPEFLEG 91 Query: 81 VNLIMQEKM-----------EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 + + + F ++D DG+G+I +E + A ++G Sbjct: 92 WKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDE----WKAYGRISGISP- 146 Query: 130 SPEEFINLVFHKIDINNDGELTLEE 154 EE F D++N GEL ++E Sbjct: 147 -SEEDCEKTFQHCDLDNSGELDVDE 170 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 56/159 (35%), Gaps = 28/159 (17%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI---------MQEKMEQKLK 94 L N K K +++ D N +G + E ++ + Q + Q Sbjct: 9 LQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCV 68 Query: 95 WYFKLYDADGNG-----SIDKNELLDMFMAVQALNGQQTLSPE-----EFINLVFHKIDI 144 F G G E L+ + + + + E E+ + VF D Sbjct: 69 EAF----FRGCGLEYGKETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDK 124 Query: 145 NNDGELTLEEF-----INGMAKDQDLLEIVYKSFDFSNV 178 + G +TL+E+ I+G++ ++ E ++ D N Sbjct: 125 DGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNS 163 >2HPS-A nrPDB Length = 186 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Query: 42 TLLGLQGLNQKANKHIDQVY-NTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLY 100 +LL ++G + + + DT+KDG+V EF A + + + + K F Sbjct: 88 SLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTL 147 Query: 101 DADGNGSIDKNELL 114 D + NG I ++E L Sbjct: 148 DFNKNGQISRDEFL 161 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 G +L EFK L G + +K I +NT D NK+G + EF+ VN + E Sbjct: 116 DGYVSLPEFKAFLQAVGPDLTDDKAIT-CFNTLDFNKNGQISRDEFLVTVNDFLFGLEET 174 Query: 92 KLKWYF 97 L F Sbjct: 175 ALANAF 180 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 51/130 (39%), Gaps = 15/130 (11%) Query: 61 YNTFDTNKDGFVDFLEF------IAAVNLIMQEKMEQKLKWYFKLYDADGNG---SIDKN 111 D DGF+ ++ IA + + EK E+ + + ++ D G I Sbjct: 20 MQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVRISVE 79 Query: 112 ELL-DMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKD-QDLLE-- 167 E + ++ + G++ +++ ID + DG ++L EF + DL + Sbjct: 80 EAAVNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDK 139 Query: 168 --IVYKSFDF 175 + + DF Sbjct: 140 AITCFNTLDF 149 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 6/57 (10%) Query: 100 YDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 D D +G + E AV L+ ++ I F+ +D N +G+++ +EF+ Sbjct: 111 IDTDKDGYVSLPEFKAFLQAV-----GPDLTDDKAI-TCFNTLDFNKNGQISRDEFL 161 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 19/54 (35%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 +K+K + D G+G I + + + + + + EE D Sbjct: 14 RKMKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQ 67 >2KYF-A nrPDB Length = 108 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M +K +LK F++ D D +G I+++EL ++ G + L+ E D Sbjct: 35 MSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFES--GARVLTASE-TKTFLAAADH 91 Query: 145 NNDGELTLEEFINGMA 160 + DG++ EEF + Sbjct: 92 DGDGKIGAEEFQEMVQ 107 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 36/82 (43%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI---MQEKMEQKLKWYF 97 K + G+++K++ + +++ D ++ GF++ E + + + K + Sbjct: 27 KKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFL 86 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 D DG+G I E +M + Sbjct: 87 AAADHDGDGKIGAEEFQEMVQS 108 >3JAX-C nrPDB Length = 151 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 58/155 (37%), Gaps = 12/155 (7%) Query: 10 DQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN-TFDTNK 68 D T E ++ F G + ++ G N + + + N D Sbjct: 3 DFSEEQTAEFKEAFQLFDR-TGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMN 61 Query: 69 DGFVDFLEFIAAVNLIMQEKME---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 + F +F+ + I + K + + +++D +GNG++ E+ + + + Sbjct: 62 LKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTL----- 116 Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 + ++ EE LV D N G + EE + + Sbjct: 117 GEKMTEEEVEQLVAGHEDSN--GCINYEELVRMVL 149 >1OQP-A nrPDB Length = 77 Score = 50.4 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + +++ F+L+D D +G+I +L + + EE + + + D Sbjct: 3 GERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLT------EEELQEMIAEADR 56 Query: 145 NNDGELTLEEFINGMAK 161 N+D E+ +EFI M K Sbjct: 57 NDDNEIDEDEFIRIMKK 73 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 28/67 (41%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + + I + + FD + G + + + + E++L+ D + + ID++ Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDED 65 Query: 112 ELLDMFM 118 E + + Sbjct: 66 EFIRIMK 72 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 30/77 (38%), Gaps = 2/77 (2%) Query: 9 GDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 G + +E +R F + SG T+ + + + G N + + ++ D N Sbjct: 1 GSGERDSREEILKAFRLF-DDDNSGTITIKDLRRVAKELGENLT-EEELQEMIAEADRND 58 Query: 69 DGFVDFLEFIAAVNLIM 85 D +D EFI + Sbjct: 59 DNEIDEDEFIRIMKKTS 75 >3KPX-A nrPDB Length = 198 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 26/58 (44%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 + V++ FD + G + E+ + ++ + FK D D +G +D +E+ Sbjct: 119 EAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 55/149 (36%), Gaps = 26/149 (17%) Query: 26 FMMEYPSGLQTLHEF---------KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 F+ +G TL E L Q+ + ++ + + V+F Sbjct: 31 FLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKEVEFPA 90 Query: 77 FIAAVNLIMQEKME-----QKL------KWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 F+ + + ++ +K + F ++D DG+GSI +E ++G Sbjct: 91 FVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWKTY----GGISG 146 Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEE 154 +E F D++N G+L ++E Sbjct: 147 I--CPSDEDAEKTFKHCDLDNSGKLDVDE 173 Score = 35.4 bits (80), Expect = 0.016, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 94 KWYFKLYDADGNGSIDKNEL----LDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 K+ F D +GNG I +E+ D A QT +E + F KI ++ E Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKE 85 Query: 150 LTLEEFING 158 + F+NG Sbjct: 86 VEFPAFVNG 94 Score = 34.6 bits (78), Expect = 0.027, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 60/168 (35%), Gaps = 24/168 (14%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNL----------IM 85 T ++ L + K ++N D N +G + E ++ + Sbjct: 4 TASKYAVKLKTNFEDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQ 63 Query: 86 QEKMEQKLKWYFKLYDADGNGSIDK-------NELLDMFMAVQALNGQQTLSPEEFINLV 138 ++ ++ ++ +FK D ++ EL ++ + + + V Sbjct: 64 TQRHQEAVEAFFKKIGLDYGKEVEFPAFVNGWKELAK--HDLKLWSQNKKSLIRNWGEAV 121 Query: 139 FHKIDINNDGELTLEEF-----INGMAKDQDLLEIVYKSFDFSNVLRV 181 F D + G ++L+E+ I+G+ + E +K D N ++ Sbjct: 122 FDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKL 169 >3AKA-A nrPDB Length = 166 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP---------EEFINLVFH 140 E+++ F +D DGNG ID+++ A+ A G S E + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 141 KIDINNDGELTLEEFINGMAK 161 D + D +T EEF+ G K Sbjct: 63 IADRDGDQRITREEFVTGAVK 83 Score = 45.0 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 27/162 (16%), Positives = 52/162 (32%), Gaps = 30/162 (18%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEF----KTLLGLQG----------LNQKANKHIDQVY 61 + + TF + +G +F K LL G L A + Sbjct: 3 ERRIAARFTTFDQD-GNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLA 61 Query: 62 NTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ-------KLKWYFKLYDADGNGSIDKNELL 114 D + D + EF+ +++K ++ L + D DG+G++ + Sbjct: 62 GIADRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTA 121 Query: 115 DMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 A PE+ +D + DG++ E + Sbjct: 122 RALTAFG--------VPEDLARQAAAALDTDGDGKVGETEIV 155 >1SR6-C nrPDB Length = 156 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 59/161 (36%), Gaps = 20/161 (12%) Query: 13 AVPTQETHVWYRTFMM----EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 + E F + + G + + G+N + + V+ T+K Sbjct: 2 KLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRN----EDVFAVGGTHK 57 Query: 69 DG--FVDFLEFIAAVNLIMQ--EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 G + F EF+ A +M + FK +D +G G I EL + A+ Sbjct: 58 MGEKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTAL---- 113 Query: 125 GQQTLSPEEFINLVFHKIDINND--GELTLEEFINGMAKDQ 163 + LS E+ ++ + D+ D G + E+F+ + Sbjct: 114 -GERLSDED-VDEIIKLTDLQEDLEGNVKYEDFVKKVMAGP 152 >1QXP-A nrPDB Length = 900 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 61/177 (34%), Gaps = 29/177 (16%) Query: 10 DQKAVPTQETHVWYRTFMMEY--PSGLQTLHEFKTLLGL-------QGLNQKANKHIDQV 60 D+K + +E ++T + ++ E +T+L N + + + Sbjct: 523 DEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSM 582 Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 120 N D + +G + +EF N I F+ +D D +GS+ E+ A Sbjct: 583 VNLMDRDGNGKLGLVEFNILWNRIRNYLT------IFRKFDLDKSGSMSAYEMRMAIEAA 636 Query: 121 Q---ALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 Q + + + + + F+ + + + L +I +K D Sbjct: 637 GFKLPCQLHQVIVARFADDELI----------IDFDNFVRCLVRLEILFKI-FKQLD 682 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 52/132 (39%), Gaps = 6/132 (4%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFK-LYDA--DGNGSI 108 + NK D + F K G + + I A + E+++ FK L+ + I Sbjct: 491 EPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEI 550 Query: 109 DKNELLDMFMAVQALNGQQTLS--PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 EL + + + + + E + + +D + +G+L L EF + ++ L Sbjct: 551 SVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYL 610 Query: 167 EIVYKSFDFSNV 178 +++ FD Sbjct: 611 -TIFRKFDLDKS 621 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 45/117 (38%), Gaps = 14/117 (11%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + D++ G + F EF N I + + +K ++ D +G+I NEL F Sbjct: 777 RSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQG------IYKRFETDRSGTIGSNELPGAF 830 Query: 118 MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 A Q S ++ D G + + FI+ + + + ++S D Sbjct: 831 EAAGFHLNQHIYSM-----IIRRYSDET--GNMDFDNFISCLVRLDAMFRA-FRSLD 879 Score = 40.0 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 34/95 (35%), Gaps = 9/95 (9%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 ++ Y+ F + SG +E G + + + + D + +DF Sbjct: 804 KKWQGIYKRFETDR-SGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGN--MDFDN 860 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 FI+ + + + F+ D +G G I N Sbjct: 861 FISCLVRL------DAMFRAFRSLDKNGTGQIQVN 889 >3J04-B nrPDB Length = 143 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 20/147 (13%), Positives = 54/147 (36%), Gaps = 13/147 (8%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + + + G + +L G N +++++ + + G ++F Sbjct: 5 QIQEFKEAF-NMIDQNRDGFIDKEDLHDMLASMGKNPT-DEYLEGMMSEA----PGPINF 58 Query: 75 LEFIAAVNLIMQEKM-EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 F+ + E ++ F +D + +G I ++ L ++ + +E Sbjct: 59 TMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFT------DE 112 Query: 134 FINLVFHKIDINNDGELTLEEFINGMA 160 ++ ++ + I+ G EF + Sbjct: 113 EVDEMYREAPIDKKGNFNYVEFTRILK 139 >1SL8-A nrPDB Length = 191 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 28/58 (48%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D +++ D +++G + E+ A + + + F++ D D +G +D +E+ Sbjct: 112 DALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 35/93 (37%), Gaps = 17/93 (18%) Query: 73 DFLEFIAAVNLIMQEKMEQKLK-----------WYFKLYDADGNGSIDKNELLDMFMAVQ 121 ++ E+I + E++++ K F + D D NG+I +E + Sbjct: 80 EWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTKSAG 139 Query: 122 ALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 + + F DI+ G+L ++E Sbjct: 140 IIQSSEDC------EETFRVCDIDESGQLDVDE 166 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 42/119 (35%), Gaps = 19/119 (15%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIM---------QEKMEQKLKWYFKLYDADGNGSID 109 ++N D N +G + E + + I+ Q K + F + G Sbjct: 20 HMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAF--FGGAGMKYGV 77 Query: 110 KNELLDMFMAVQALNGQQTLSPEE--------FINLVFHKIDINNDGELTLEEFINGMA 160 + E + + L ++ + + + +F ID + +G ++L+E+ Sbjct: 78 ETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTK 136 Score = 27.7 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 19/50 (38%), Gaps = 4/50 (8%) Query: 94 KWYFKLYDADGNGSIDKNEL----LDMFMAVQALNGQQTLSPEEFINLVF 139 K F D + NG I +E+ D+ + +Q ++ + F Sbjct: 19 KHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFF 68 Score = 26.5 bits (57), Expect = 9.5, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 20/33 (60%), Gaps = 3/33 (9%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +F+ +D+N++G ++L+E + K D++ Sbjct: 17 RHKHMFNFLDVNHNGRISLDE---MVYKASDIV 46 >1S36-A nrPDB Length = 195 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 30/82 (36%), Gaps = 2/82 (2%) Query: 34 LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKL 93 E K + D V++ FD + G + E+ A + ++ Sbjct: 94 QLATSELKKWAR--NEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDC 151 Query: 94 KWYFKLYDADGNGSIDKNELLD 115 + F+ D D +G +D +E+ Sbjct: 152 EATFRHCDLDNSGDLDVDEMTR 173 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 59/155 (38%), Gaps = 20/155 (12%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWY------- 96 L N + K +++ D N +G + E ++ + + K+E + Sbjct: 9 LKTDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCV 68 Query: 97 ---FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE-----EFINLVFHKIDINNDG 148 F+ + I + LD F + ++ E E+ + VF D + G Sbjct: 69 EAFFRGCGMEYGKEIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSG 128 Query: 149 ELTLEEF-----INGMAKDQDLLEIVYKSFDFSNV 178 +TL+E+ I+G++ Q+ E ++ D N Sbjct: 129 TITLDEWKAYGKISGISPSQEDCEATFRHCDLDNS 163 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 24/150 (16%), Positives = 54/150 (36%), Gaps = 26/150 (17%) Query: 25 TFMMEYPSGLQTLHEF---------KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 F+ +G TL E L ++ ++ + + F Sbjct: 27 DFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKEIAFP 86 Query: 76 EFIAAVNLIMQEKMEQKLK-----------WYFKLYDADGNGSIDKNELLDMFMAVQALN 124 +F+ + ++++ + F ++D DG+G+I +E + A ++ Sbjct: 87 QFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDE----WKAYGKIS 142 Query: 125 GQQTLSPEEFINLVFHKIDINNDGELTLEE 154 G +E F D++N G+L ++E Sbjct: 143 GISP--SQEDCEATFRHCDLDNSGDLDVDE 170 >2K7B-A nrPDB Length = 76 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 83 LIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKI 142 ++ + ++L+ F+ +D D +G I+ +L + + + + L + +I Sbjct: 2 RSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELI------ELSQQI 55 Query: 143 DINNDGELTLEEFINGM 159 ++N G + ++F+ M Sbjct: 56 NMNLGGHVDFDDFVELM 72 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 32/70 (45%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 108 L + + + + + FD +KDG+++ + + + E +L + + + G + Sbjct: 4 LRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHV 63 Query: 109 DKNELLDMFM 118 D ++ +++ Sbjct: 64 DFDDFVELMG 73 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 2/69 (2%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 +E +R F + G + + G + I+ + + N G VDF + Sbjct: 10 EELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGHVDFDD 67 Query: 77 FIAAVNLIM 85 F+ + + Sbjct: 68 FVELMGPKL 76 >6IIE-A nrPDB Length = 93 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE---FINLVFHKID 143 + E KL++ FKLYD D NG +D +E+ + + + + E + + +ID Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Query: 144 INNDGELTLEEFIN 157 + G ++ E++ Sbjct: 65 YDGSGSVSQAEWVR 78 Score = 35.8 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 32/73 (43%), Gaps = 9/73 (12%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ---------EKMEQKLKWYFKL 99 + ++ + +DT+++G +D E + +M+ ++ L+ K Sbjct: 3 EGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKE 62 Query: 100 YDADGNGSIDKNE 112 D DG+GS+ + E Sbjct: 63 IDYDGSGSVSQAE 75 >2NCO-A nrPDB Length = 102 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP-EEFINLVFHKIDINNDGELTL 152 + FK YD DG+G + +E+ + A G +P +E + + D N+DG ++L Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSL 77 Query: 153 EEFINGMAK 161 EE+ + + K Sbjct: 78 EEYEDLIIK 86 Score = 29.6 bits (65), Expect = 0.97, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 27/68 (39%), Gaps = 7/68 (10%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE-------KMEQKLKWYFKLYDADGNGSID 109 +++ +D + G + E + E ++ +K + ++ D + +GS+ Sbjct: 17 ARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVS 76 Query: 110 KNELLDMF 117 E D+ Sbjct: 77 LEEYEDLI 84 >6FSA-D nrPDB Length = 199 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 53/148 (35%), Gaps = 12/148 (8%) Query: 15 PTQETHVWYRTF-MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV- 72 +E + F T + +L G N + + + + + Sbjct: 54 QIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMM 113 Query: 73 DFLEFIAAVNLIMQEK---MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 DF F+ + I + K + +++D +GNG++ EL + + + L Sbjct: 114 DFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-----GEKL 168 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFIN 157 + +E L+ + D N G + E F+ Sbjct: 169 TEDEVEKLMAGQEDSN--GCINYEAFVK 194 >4NQG-A nrPDB Length = 197 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 28/58 (48%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D +++ D + +G V E+I + ++ + + F D DG+G +D +E+ Sbjct: 117 DALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 51/151 (33%), Gaps = 30/151 (19%) Query: 26 FMMEYPSGLQTLHEF-----KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF------ 74 F+ +G L+E + G ++ + + D +++ Sbjct: 29 FLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVE--DFFGGAGLEYDKDTTW 86 Query: 75 LEFIAAVNLIMQEKMEQKLK-----------WYFKLYDADGNGSIDKNELLDMFMAVQAL 123 E+I + + ++E+ K F + D DGNGS+ +E + Sbjct: 87 PEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQ 146 Query: 124 NGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 + F D++ DG+L ++E Sbjct: 147 QSRGQC------EATFAHCDLDGDGKLDVDE 171 Score = 33.1 bits (74), Expect = 0.094, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 15/125 (12%) Query: 48 GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM---------EQKLKWYF- 97 N K ++N D N +G ++ E + + I+ +K+ QK F Sbjct: 14 FDNPKWIARHKHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFF 73 Query: 98 ----KLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI-NLVFHKIDINNDGELTL 152 YD D + + + ++ + +F ID + +G ++L Sbjct: 74 GGAGLEYDKDTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSL 133 Query: 153 EEFIN 157 +E+I Sbjct: 134 DEWIQ 138 Score = 33.1 bits (74), Expect = 0.098, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 29/72 (40%), Gaps = 4/72 (5%) Query: 94 KWYFKLYDADGNGSIDKNELLD----MFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149 K F D + NG I+ NE++ + +QT ++ + F + D + Sbjct: 24 KHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLEYDKD 83 Query: 150 LTLEEFINGMAK 161 T E+I G + Sbjct: 84 TTWPEYIEGWKR 95 >2LVV-A nrPDB Length = 226 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 15/159 (9%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHE-FKTLLGLQGLNQKANKHIDQVYNTF 64 +I D+ A ++ F +G E G+ L++ D V F Sbjct: 40 AIPRDKDAESKSRRIELFKQFDTN-GTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAF 98 Query: 65 DTNKD--------GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 D KD G D +EF+ ++ +L F D DG+ ++ E + Sbjct: 99 DKAKDLGNKVKGVGEEDLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEFKEA 158 Query: 117 FMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 ++ T + VF++ID N G +T +EF Sbjct: 159 LPKLKEWGVDITDAT-----TVFNEIDTNGSGVVTFDEF 192 Score = 33.5 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 44/116 (37%), Gaps = 16/116 (13%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAV--NLIMQEKMEQKLKWYFKLYDADGN--------GSI 108 +++ FDTN G + F E + L + E + +D + G Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEE 114 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 D E L+ + + + L+ ++F +D + L L+EF + K ++ Sbjct: 115 DLVEFLEFRLMLCYIYDIFELT------VMFDTMDKDGSLLLELQEFKEALPKLKE 164 >4OKH-A nrPDB Length = 189 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 50/157 (31%), Gaps = 22/157 (14%) Query: 7 IAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLL-------GLQGLNQKANKHIDQ 59 + DQ++ Q+ ++ + E K +L + + Sbjct: 2 GSSDQESEEQQQFRNIFKQIAGDDME--ICADELKKVLNTVVNKHKDLKTHGFTLESCRS 59 Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 + DT+ G ++ EF N I + FK YD D +G+I+ E+ + Sbjct: 60 MIALMDTDGSGKLNLQEFHHLWNKIKAWQK------IFKHYDTDQSGTINSYEMRNAVND 113 Query: 120 VQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 Q + D + + + + FI Sbjct: 114 AGFHLNNQLYDI-----ITMRYADKHMN--IDFDSFI 143 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 38/107 (35%), Gaps = 10/107 (9%) Query: 19 THVWYRTFM--MEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 W + F SG +E + + G + + + +K +DF Sbjct: 84 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLY--DIITMRYADKHMNIDFDS 141 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL 123 FI + + + F +D DG+G I N L + + + AL Sbjct: 142 FICCFVRL------EGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYAL 182 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 14/119 (11%), Positives = 38/119 (31%), Gaps = 21/119 (17%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME--------QKLKW 95 +G + + ++ + D + E +N ++ + + + + Sbjct: 1 MGSSDQESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRS 59 Query: 96 YFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 L D DG+G ++ E ++ + + +F D + G + E Sbjct: 60 MIALMDTDGSGKLNLQEFHHLWNKI------------KAWQKIFKHYDTDQSGTINSYE 106 Score = 34.2 bits (77), Expect = 0.044, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 36/87 (41%), Gaps = 4/87 (4%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS--PEEFINLVFHKIDINND 147 +Q+ + FK D + I +EL + V + E + +D + Sbjct: 11 QQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGS 69 Query: 148 GELTLEEFINGMAKDQDLLEIVYKSFD 174 G+L L+EF + K + +I +K +D Sbjct: 70 GKLNLQEFHHLWNKIKAWQKI-FKHYD 95 >1UHK-A nrPDB Length = 191 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 28/58 (48%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D +++ D +++G + E+ A + + + F++ D D +G +D +E+ Sbjct: 112 DALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 F + D D NG+I +E A + + F DI+ G+L ++E Sbjct: 115 FDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDC------EETFRVCDIDESGQLDVDE 166 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 41/120 (34%), Gaps = 19/120 (15%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAVNLIM---------QEKMEQKLKWYF-------KLYDA 102 ++N D N +G + E + + I+ Q K + F + Sbjct: 20 HMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMKYGVET 79 Query: 103 DGNGSIDK-NELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 D I+ +L ++ + + + +F +D + +G +TL+E+ Sbjct: 80 DWPAYIEGWKKLAT--DELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKA 137 Score = 28.1 bits (61), Expect = 2.6, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 19/50 (38%), Gaps = 4/50 (8%) Query: 94 KWYFKLYDADGNGSIDKNEL----LDMFMAVQALNGQQTLSPEEFINLVF 139 K F D + NG I +E+ D+ + +Q ++ + F Sbjct: 19 KHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFF 68 Score = 26.5 bits (57), Expect = 8.5, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 21/33 (63%), Gaps = 3/33 (9%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMAKDQDLL 166 +F+ +D+N++G+++L+E + K D++ Sbjct: 17 RHKHMFNFLDVNHNGKISLDE---MVYKASDIV 46 >5B7X-A nrPDB Length = 156 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 53/141 (37%), Gaps = 3/141 (2%) Query: 6 SIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFD 65 S+ + TQ+ + + +Y G + + TL+ G ++ F Sbjct: 2 SMEIEAPNANTQKIRDCFNFYDRDYD-GKIDVKQLGTLIRSLGC-APTEDEVNSYIKEFA 59 Query: 66 TNKDGF-VDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 + F ++ E I + E KL+ F+++D D +G I ++L V Sbjct: 60 IEGETFQIEQFELIMEREQSKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTTVGDKM 119 Query: 125 GQQTLSPEEFINLVFHKIDIN 145 ++ + I + + DI+ Sbjct: 120 TKEEVEKVFSILGITMESDID 140 >2K2I-A nrPDB Length = 79 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 83 LIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKI 142 + ++ ++++ FKL+D D G I L + + + L+ EE + + + Sbjct: 3 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-----GENLTDEE-LQEMIDEA 56 Query: 143 DINNDGELTLEEFINGMAK 161 D + DGE++ +EF+ M K Sbjct: 57 DRDGDGEVSEQEFLRIMKK 75 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 29/69 (42%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSID 109 + + I + + FD ++ G + F + + +++L+ D DG+G + Sbjct: 6 EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVS 65 Query: 110 KNELLDMFM 118 + E L + Sbjct: 66 EQEFLRIMK 74 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 + +E ++ F + +G + K + G N ++ + ++ + D + DG Sbjct: 5 SEKDTKEEILKAFKLF-DDDETGKISFKNLKRVAKELGENLT-DEELQEMIDEADRDGDG 62 Query: 71 FVDFLEFIAAVNLIM 85 V EF+ + Sbjct: 63 EVSEQEFLRIMKKTS 77 >5VE9-A nrPDB Length = 91 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 34/87 (39%), Gaps = 8/87 (9%) Query: 76 EFIAAVNLIMQEKMEQKLKWY--FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 +F M+ +K + F+ D D +G I + E +D +A + + ++ Sbjct: 10 DFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVA 69 Query: 134 FINLVFHKIDINNDGELTLEEFINGMA 160 I D + DG + EF+ + Sbjct: 70 DI------FDRDGDGYIDYYEFVAALH 90 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 24/53 (45%) Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 + D ++DG + EFI + + ++ ++D DG+G ID E Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEF 85 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 G T EF + L + V + FD + DG++D+ EF+AA++ Sbjct: 41 DGKITRQEFIDGI-LASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALH 90 Score = 32.3 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 134 FINLVFHKIDINNDGELTLEEFINGMAKDQ 163 + F +ID + DG++T +EFI+G+ + Sbjct: 28 RVMDFFRRIDKDQDGKITRQEFIDGILASK 57 >5ZH6-A nrPDB Length = 107 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 30/77 (38%), Gaps = 3/77 (3%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + K + L F + D D +G I+ +EL A E N D Sbjct: 34 LTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATA---RELDETETNAFLAAGDS 90 Query: 145 NNDGELTLEEFINGMAK 161 ++DG++ ++EF + Sbjct: 91 DHDGKIGVDEFKAMVKA 107 Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWYF 97 KT GL K++ ++ +V++ D ++ GF++ E F+ + +E E + + Sbjct: 26 KTFFVTSGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFL 85 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 D+D +G I +E M A Sbjct: 86 AAGDSDHDGKIGVDEFKAMVKA 107 >5TBY-C nrPDB Length = 195 Score = 46.9 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 53/148 (35%), Gaps = 12/148 (8%) Query: 15 PTQETHVWYRTF-MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV- 72 +E + F T + +L G N + + + + + Sbjct: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 Query: 73 DFLEFIAAVNLIMQEK---MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 DF F+ + I + K + +++D +GNG++ EL + + + L Sbjct: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-----GERL 164 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFIN 157 + +E L+ + D N G + E F+ Sbjct: 165 TEDEVEKLMAGQEDSN--GCINYEAFVK 190 >5H53-C nrPDB Length = 153 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 60/153 (39%), Gaps = 13/153 (8%) Query: 11 QKAVPTQETHVWYRTFMMEYPSG--LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNK 68 + ++ + F++ +G TL + +L G N + + N + Sbjct: 2 KIEFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEM 61 Query: 69 DGF-VDFLEFIAAVNLIMQEKME---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 + ++F +F+ + I K + + +++D +GNG++ EL + + Sbjct: 62 NAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL---- 117 Query: 125 GQQTLSPEEFINLVFHKIDINNDGELTLEEFIN 157 + + EE L+ + D N G + E F+ Sbjct: 118 -GEKMKEEEVEALMAGQEDSN--GCINYEAFVK 147 >3TZ1-A nrPDB Length = 74 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 7/79 (8%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 M++ E++LK F++ D + G I + L + ++ E+ I + + D Sbjct: 1 MEDLDERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELT------EDEIENMIAETDT 54 Query: 145 NNDGELTLEEF-INGMAKD 162 + G + EEF M+ D Sbjct: 55 DGSGTVDYEEFKCLMMSSD 73 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 29/70 (41%), Gaps = 2/70 (2%) Query: 12 KAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF 71 + + +E +R E G+ + + +L G ++ I+ + DT+ G Sbjct: 2 EDLDERELKEAFRVLDKE-KKGVIKVDVLRWILKSLG-DELTEDEIENMIAETDTDGSGT 59 Query: 72 VDFLEFIAAV 81 VD+ EF + Sbjct: 60 VDYEEFKCLM 69 Score = 35.0 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 27/66 (40%) Query: 54 NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 + + + + D K G + + + E E +++ D DG+G++D E Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEF 65 Query: 114 LDMFMA 119 + M+ Sbjct: 66 KCLMMS 71 >1QX2-A nrPDB Length = 76 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Query: 88 KMEQKLKWYFKLYD-ADGN-GSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 K +++K F+++ +G+ I K EL + + G L ++ + ++D N Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTL----GPSLLKGMSTLDEMIEEVDKN 57 Query: 146 NDGELTLEEFINGMAKD 162 DGE++ EEF+ M K Sbjct: 58 GDGEVSFEEFLVMMKKI 74 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 29/74 (39%), Gaps = 2/74 (2%) Query: 15 PTQETHVWYRTFM-MEYPSGLQTLHEFKTLLGLQGLNQ-KANKHIDQVYNTFDTNKDGFV 72 +E + F E + E K ++ G + K +D++ D N DG V Sbjct: 3 SPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEV 62 Query: 73 DFLEFIAAVNLIMQ 86 F EF+ + I Q Sbjct: 63 SFEEFLVMMKKISQ 76 Score = 26.5 bits (57), Expect = 7.6, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 25/74 (33%), Gaps = 4/74 (5%) Query: 51 QKANKHIDQVYNTFDTNKD--GFVDFLEFIAAVNLIMQEKMEQK--LKWYFKLYDADGNG 106 K+ + I + F + + E + + ++ L + D +G+G Sbjct: 1 MKSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDG 60 Query: 107 SIDKNELLDMFMAV 120 + E L M + Sbjct: 61 EVSFEEFLVMMKKI 74 >1N2D-A nrPDB Length = 148 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 20/138 (14%), Positives = 57/138 (41%), Gaps = 14/138 (10%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 G L G N N+ + + N + +D L+ I + + +++++ Sbjct: 17 GQGAIAKDSLGDYLRAIGYNPT-NQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELD 75 Query: 91 -------QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKID 143 + F+++D + G + +L M + + L+ E ++ + ++ Sbjct: 76 ATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGL-----GEKLTDAE-VDELLKGVE 129 Query: 144 INNDGELTLEEFINGMAK 161 ++++GE+ ++FI + + Sbjct: 130 VDSNGEIDYKKFIEDVLR 147 Score = 28.8 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 35/88 (39%), Gaps = 4/88 (4%) Query: 28 MEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 ++ +GL ++E L + + + + FD G V + + + ++ Sbjct: 60 LDQITGLIEVNE----KELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEK 115 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLD 115 + ++ K + D NG ID + ++ Sbjct: 116 LTDAEVDELLKGVEVDSNGEIDYKKFIE 143 Score = 27.3 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 34/90 (37%), Gaps = 7/90 (7%) Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 K F L+D G G+I K+ L D A+ Q + + LTL+ Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDA-----SSLTLD 61 Query: 154 EFINGMAKDQDLLEIVYKSF--DFSNVLRV 181 + + ++ L+ K+ DF +V Sbjct: 62 QITGLIEVNEKELDATTKAKTEDFVKAFQV 91 >1KFU-L nrPDB Length = 699 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 50/147 (34%), Gaps = 21/147 (14%) Query: 35 QTLHEFKTLLGLQ-------GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 + E +T+L + + + + + D++ G + EF I Sbjct: 547 ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI--- 603 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 QK + ++ D D +G+++ E+ Q +V D Sbjct: 604 ---QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQV-----IVARFADDQL- 654 Query: 148 GELTLEEFINGMAKDQDLLEIVYKSFD 174 + + F+ + + + L +I +K D Sbjct: 655 -IIDFDNFVRCLVRLETLFKI-FKQLD 679 Score = 33.8 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 47/137 (34%), Gaps = 17/137 (12%) Query: 52 KANKHIDQVYNTFDTNK------DGFVDF--LEFIAAVNLIMQEKMEQKLKWYFKLYDAD 103 + NK D F K D ++ EF I ++ ++ ++ F A Sbjct: 489 EPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEF-----DISEDDIDDGVRRLFAQL-AG 542 Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLS--PEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + I EL + V A E ++ +D + G+L L+EF K Sbjct: 543 EDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK 602 Query: 162 DQDLLEIVYKSFDFSNV 178 Q +I Y+ D Sbjct: 603 IQKYQKI-YREIDVDRS 618 >2N8Y-A nrPDB Length = 153 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 5/106 (4%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + I QE+M + + F +D D +G++ E +++ G EF + Sbjct: 2 SSISQEQMNE-FRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFA-RIMSI 59 Query: 142 IDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQ 187 +D N G +T + FI+ M+++ + + +++ K Sbjct: 60 VDPNRLGVVTFQAFIDFMSRETADTDTADQVM---ASFKILAGDKN 102 Score = 33.8 bits (76), Expect = 0.056, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 40/120 (33%), Gaps = 11/120 (9%) Query: 49 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI-----MQEKMEQKLKWYFKLYDAD 103 ++Q+ +N FD + G + EF A + + + E + + D + Sbjct: 4 ISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPN 63 Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 G + +D A + + + D N +T++E + DQ Sbjct: 64 RLGVVTFQAFIDFMSRETA---DTDTADQVMASFKILAGDKN---YITMDELRRELPPDQ 117 >3CS1-A nrPDB Length = 219 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 61/160 (38%), Gaps = 15/160 (9%) Query: 5 KSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHE-FKTLLGLQGLNQKANKHIDQVYNT 63 ++I ++ A Q ++ F +G E + L + L++ ++ D Sbjct: 36 QAIPREKTAEAKQRRIELFKKFDKN-ETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRA 94 Query: 64 FDT--------NKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 FD G DF+EF+ ++ +L F DA GN +D+ E Sbjct: 95 FDKSRTLGSKLENKGSEDFVEFLEFRLMLCYIYDFFELTVMFDEIDASGNMLVDEEEFKR 154 Query: 116 MFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 ++A + E +F ++D N G +T +EF Sbjct: 155 AVPKLEA-----WGAKVEDPAALFKELDKNGTGSVTFDEF 189 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 34/83 (40%), Gaps = 2/83 (2%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME-QKLKWYFKLYDADGNGSIDKNELL 114 + +++ D + + VD EF AV + + + FK D +G GS+ +E Sbjct: 131 ELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFA 190 Query: 115 DMFMAVQ-ALNGQQTLSPEEFIN 136 AV+ +G PE + Sbjct: 191 AWASAVKLDADGDPDNVPESALE 213 Score = 30.8 bits (68), Expect = 0.44, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 18/51 (35%) Query: 34 LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 L EFK + + ++ D N G V F EF A + + Sbjct: 146 LVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFAAWASAV 196 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 D DG + D+ E + QA+ ++T ++ +F K D N G+L +E +G Sbjct: 18 DKDGKKAKDRKEAWERIR--QAIPREKTAEAKQRRIELFKKFDKNETGKLCYDEVYSGCL 75 Query: 161 KDQDLLEIVYKSFDFSN 177 + L E + D + Sbjct: 76 EVLKLDEFTSRVRDITK 92 Score = 26.1 bits (56), Expect = 9.9, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 16/115 (13%) Query: 59 QVYNTFDTNKDGFVDFLEFIAAV--NLIMQEKMEQKLKWYFKLYDA--------DGNGSI 108 +++ FD N+ G + + E + L + E + + +D + GS Sbjct: 52 ELFKKFDKNETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSE 111 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 D E L+ + + + L+ ++F +ID + + + EEF + K + Sbjct: 112 DFVEFLEFRLMLCYIYDFFELT------VMFDEIDASGNMLVDEEEFKRAVPKLE 160 >2NLN-A nrPDB Length = 108 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 3/76 (3%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + + ++K F+ D D +G +D +EL +Q E + D Sbjct: 35 LSKMSASQVKDIFRFIDNDQSGYLDGDELKYF---LQKFQSDARELTESETKSLMDAADN 91 Query: 145 NNDGELTLEEFINGMA 160 + DG++ +EF + Sbjct: 92 DGDGKIGADEFQEMVH 107 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 36/87 (41%), Gaps = 3/87 (3%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQK 92 E + GL++ + + ++ D ++ G++D E F+ +E E + Sbjct: 22 DTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESE 81 Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMA 119 K D DG+G I +E +M + Sbjct: 82 TKSLMDAADNDGDGKIGADEFQEMVHS 108 Score = 33.5 bits (75), Expect = 0.063, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 20/60 (33%), Gaps = 2/60 (3%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQGLNQKA--NKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 F+ SG E K L + + + + D + DG + EF V+ Sbjct: 48 RFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEMVH 107 >3DF0-A nrPDB Length = 714 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 49/150 (32%), Gaps = 27/150 (18%) Query: 35 QTLHEFKTLLGLQ-------GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQE 87 + E +T+L + + + + + D + G + EF I Sbjct: 548 ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI--- 604 Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQ---ALNGQQTLSPEEFINLVFHKIDI 144 QK + ++ D D +G+++ E+ Q + + + Sbjct: 605 ---QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELI----- 656 Query: 145 NNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 + + F+ + + + L +I +K D Sbjct: 657 -----IDFDNFVRCLVRLEILFKI-FKQLD 680 Score = 33.8 bits (76), Expect = 0.057, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 27/76 (35%), Gaps = 3/76 (3%) Query: 105 NGSIDKNELLDMFMAVQALNGQQTLS--PEEFINLVFHKIDINNDGELTLEEFINGMAKD 162 + I EL + V A E ++ +D + G+L L+EF K Sbjct: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 Query: 163 QDLLEIVYKSFDFSNV 178 Q +I Y+ D Sbjct: 605 QKYQKI-YREIDVDRS 619 Score = 33.5 bits (75), Expect = 0.060, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 47/132 (35%), Gaps = 26/132 (19%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV--- 81 + E SG L EF L + ++Y D ++ G ++ E A+ Sbjct: 582 DMLDEDGSGKLGLKEFYILW-------TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + ++ Q + F AD ID + + + + E + +F + Sbjct: 635 GFKLPCQLHQVIVARF----ADDELIIDFDNFVRCLVRL------------EILFKIFKQ 678 Query: 142 IDINNDGELTLE 153 +D N G + L+ Sbjct: 679 LDPENTGTIQLD 690 >1KFX-S nrPDB Length = 184 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 60/171 (35%), Gaps = 22/171 (12%) Query: 12 KAVPTQETHVWYRTFMMEYPSGL-QTLHEFKTLLGL-------QGLNQKANKHIDQVYNT 63 +A ++E + R F + + E +L + + Sbjct: 7 EANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAV 66 Query: 64 FDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQAL 123 D++ G + F EF N I + + +K +D D +G+I +EL F A Sbjct: 67 MDSDTTGKLGFEEFKYLWNNIKRWQA------IYKQFDTDRSGTICSSELPGAFEAAGFH 120 Query: 124 NGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 + N++ + + G + + FI+ + + + +KS D Sbjct: 121 LNEHLY------NMIIRRY-SDESGNMDFDNFISCLVRLDAMFRA-FKSLD 163 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 45/130 (34%), Gaps = 22/130 (16%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +G EFK L +Y FDT++ G + E A E Sbjct: 72 TGKLGFEEFKYLWNNIKRW-------QAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEH 124 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL- 150 + Y +D +G++D + + + + A+ F +D + G++ Sbjct: 125 LYNMIIRRY-SDESGNMDFDNFISCLVRLDAMF------------RAFKSLDKDGTGQIQ 171 Query: 151 -TLEEFINGM 159 ++E++ Sbjct: 172 VNIQEWLQLT 181 >5I2L-A nrPDB Length = 120 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 14/93 (15%) Query: 69 DGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT 128 + + +F EF K + ++ FK YDA +G ID EL M + A Sbjct: 17 NPYTEFKEF--------SRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLG 68 Query: 129 LSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 L + ++D + D +L+ EF+ K Sbjct: 69 L------KNMIKEVDEDFDSKLSFREFLLIFRK 95 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 37/82 (45%) Query: 47 QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNG 106 + ++K K +++++ +D +DGF+D +E + + + LK K D D + Sbjct: 23 KEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDS 82 Query: 107 SIDKNELLDMFMAVQALNGQQT 128 + E L +F A Q+ Sbjct: 83 KLSFREFLLIFRKAAAGELQED 104 >2KQY-A nrPDB Length = 108 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWY 96 +K+ GL+ K I +V+ D +K GF++ E F+ + + + K + Sbjct: 26 YKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAF 85 Query: 97 FKLYDADGNGSIDKNELLDMFMA 119 D DG+G I E + A Sbjct: 86 LAAGDTDGDGKIGVEEFQSLVKA 108 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Query: 73 DFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 ++ F + V L + ++K F + D D +G I++ EL + + Sbjct: 25 NYKSFFSTVGLSSKTP--DQIKKVFGILDQDKSGFIEEEELQLFLKN---FSSSARVLTS 79 Query: 133 EFINLVFHKIDINNDGELTLEEFINGMAK 161 D + DG++ +EEF + + Sbjct: 80 AETKAFLAAGDTDGDGKIGVEEFQSLVKA 108 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 20/60 (33%), Gaps = 2/60 (3%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 + + SG E + L + + + DT+ DG + EF + V Sbjct: 48 GILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKIGVEEFQSLVK 107 >1S6J-A nrPDB Length = 87 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 6/65 (9%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 LK FK+ D D +G+I +EL D V + E I + DI+ G + Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKRVGSEL------MESEIKDLMDAADIDKSGTIDY 78 Query: 153 EEFIN 157 EFI Sbjct: 79 GEFIA 83 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 27/57 (47%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 + +++ DT+ G + F E + + E ME ++K D D +G+ID E Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEF 81 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 12 KAVPTQETHVWYRTFMM--EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 + + +E F M SG T E K L G ++ I + + D +K Sbjct: 15 ERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVG-SELMESEIKDLMDAADIDKS 73 Query: 70 GFVDFLEFIAAVNL 83 G +D+ EFIAA Sbjct: 74 GTIDYGEFIAATVH 87 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 127 QTLSPEEF--INLVFHKIDINNDGELTLEEFINGMAK 161 + LS EE + +F ID +N G +T +E +G+ + Sbjct: 15 ERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKR 51 >1A75-A nrPDB Length = 108 Score = 45.0 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 3/77 (3%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + K +K F D D +G I+++EL +A G + L+ E D Sbjct: 35 LSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKA--GARALTDAE-TKAFLKAGDS 91 Query: 145 NNDGELTLEEFINGMAK 161 + DG + +EE++ + Sbjct: 92 DGDGAIGVEEWVALVKA 108 Score = 40.0 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWY 96 +K GL+ K+ I + + D +K GF++ E F+ + + + K + Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 97 FKLYDADGNGSIDKNELLDMFMA 119 K D+DG+G+I E + + A Sbjct: 86 LKAGDSDGDGAIGVEEWVALVKA 108 Score = 33.8 bits (76), Expect = 0.047, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 26 FMMEYPSGLQTLHEFKTLLGLQGLNQKA--NKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 F+ + SG E K L + +A + D++ DG + E++A V Sbjct: 49 FIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSDGDGAIGVEEWVALVK 107 >5VT9-A nrPDB Length = 152 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 22/143 (15%), Positives = 45/143 (31%), Gaps = 12/143 (8%) Query: 18 ETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 E Y F G + + L GL Q + + + F +F Sbjct: 18 EADEMYARFNARASGGKVSTGDAMILARQLGLAPSYAD--KQAFEEKSGDNLDYASFQKF 75 Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINL 137 + E + L F +D +G + + ++ ++ + + L+ EEF L Sbjct: 76 VG--TSTHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNIL-----MTYGEPLTTEEFNAL 128 Query: 138 VFHKIDINNDGELTLEEFINGMA 160 + ++ +F M Sbjct: 129 AAEYFTSD---QIDYRQFCKAML 148 >1TTX-A nrPDB Length = 109 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 27/68 (39%), Gaps = 3/68 (4%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 +K F+ D D +G +D+ EL +Q E + D + DG++ Sbjct: 44 VKDVFRFIDNDQSGYLDEEELKFF---LQKFESGARELTESETKSLMAAADNDGDGKIGA 100 Query: 153 EEFINGMA 160 EEF + Sbjct: 101 EEFQEMVH 108 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 34/87 (39%), Gaps = 3/87 (3%) Query: 36 TLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI---MQEKMEQK 92 E + GL++ + + V+ D ++ G++D E + +E E + Sbjct: 23 DTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESE 82 Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMA 119 K D DG+G I E +M + Sbjct: 83 TKSLMAAADNDGDGKIGAEEFQEMVHS 109 Score = 35.0 bits (79), Expect = 0.025, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 19/60 (31%), Gaps = 2/60 (3%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQ--GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 F+ SG E K L G + + D + DG + EF V+ Sbjct: 49 RFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVH 108 >6MI5-X nrPDB Length = 117 Score = 44.2 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 36/99 (36%), Gaps = 29/99 (29%) Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAV 120 FD +KDG +D E +AA + F D D +G++D EL Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSA------------AFDKLDPDKDGTLDAKELKGRVSEA 56 Query: 121 QALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 K+D +NDG L +E++ + Sbjct: 57 D-----------------LKKLDPDNDGTLDKKEYLAAV 78 Score = 33.5 bits (75), Expect = 0.065, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 13/67 (19%) Query: 61 YNTFDTNKDGFVDFLEFIAAVN--------LIMQEKMEQKLKWY-----FKLYDADGNGS 107 ++ D +KDG +D E V+ +++K FK + D +G+ Sbjct: 33 FDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGT 92 Query: 108 IDKNELL 114 ID EL Sbjct: 93 IDARELA 99 >5CPV-A nrPDB Length = 109 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 30/77 (38%), Gaps = 3/77 (3%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + K +K F + D D +G I+++EL +A + D Sbjct: 36 LTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKA---DARALTDGETKTFLKAGDS 92 Query: 145 NNDGELTLEEFINGMAK 161 + DG++ ++EF + Sbjct: 93 DGDGKIGVDEFTALVKA 109 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWYF 97 K GL K+ + + + D +K GF++ E F+ + + + K + Sbjct: 28 KAFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFL 87 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 K D+DG+G I +E + A Sbjct: 88 KAGDSDGDGKIGVDEFTALVKA 109 Score = 28.1 bits (61), Expect = 2.8, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 19/53 (35%), Gaps = 2/53 (3%) Query: 32 SGLQTLHEFKTLLGLQGLNQKA--NKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 SG E K L + +A + D++ DG + EF A V Sbjct: 56 SGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGDGKIGVDEFTALVK 108 >3LCP-C nrPDB Length = 93 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Query: 78 IAAVNLIMQEKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQ---TLSPEE 133 + +N E Q+L+ YFK++D DGN +D EL V G + +S +E Sbjct: 4 MGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDE 63 Query: 134 FINLV---FHKIDINNDGELTLEEFINGMA 160 IN++ D NNDG + EF + Sbjct: 64 LINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 93 Score = 28.8 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAV 81 ID V D N DG++D+ EF ++ Sbjct: 68 IDGVLRDDDKNNDGYIDYAEFAKSL 92 >4PAL-A nrPDB Length = 108 Score = 43.9 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 34/87 (39%), Gaps = 5/87 (5%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF 134 EF A V L + +K F + D D +G I+++EL +Q + + Sbjct: 27 KEFFAKVGLASKSL--DDVKKAFYVIDQDKSGFIEEDELKLF---LQNFSPSARALTDAE 81 Query: 135 INLVFHKIDINNDGELTLEEFINGMAK 161 D + DG + ++EF + Sbjct: 82 TKAFLADGDKDGDGMIGVDEFAAMIKA 108 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWYF 97 K GL K+ + + + D +K GF++ E F+ + + + + K + Sbjct: 27 KEFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFL 86 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 D DG+G I +E M A Sbjct: 87 ADGDKDGDGMIGVDEFAAMIKA 108 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 18/53 (33%), Gaps = 2/53 (3%) Query: 32 SGLQTLHEFKTLLGLQGLNQKA--NKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 SG E K L + +A + D + DG + EF A + Sbjct: 55 SGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVDEFAAMIK 107 >2MA2-A nrPDB Length = 81 Score = 43.9 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 28/73 (38%), Gaps = 7/73 (9%) Query: 54 NKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 K ++ V+ FD + DG + EF F D + +G I + E+ Sbjct: 12 EKMVESVFRNFDVDGDGHISQEEFQIIRGNF-------PYLSAFGDLDQNQDGCISREEM 64 Query: 114 LDMFMAVQALNGQ 126 + F+ ++ G Sbjct: 65 VSYFLRSSSVLGG 77 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 13/80 (16%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 146 E +E+ ++ F+ +D DG+G I + E + L+ F +D N Sbjct: 9 EHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLS-------------AFGDLDQNQ 55 Query: 147 DGELTLEEFINGMAKDQDLL 166 DG ++ EE ++ + +L Sbjct: 56 DGCISREEMVSYFLRSSSVL 75 Score = 27.7 bits (60), Expect = 3.9, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 + +R F ++ G + EF+ + G ++ + D N+DG + Sbjct: 12 EKMVESVFRNFDVD-GDGHISQEEFQIIRGNF-------PYLSA-FGDLDQNQDGCISRE 62 Query: 76 EFIAAVNLIMQ 86 E ++ Sbjct: 63 EMVSYFLRSSS 73 >1RTP-1 nrPDB Length = 109 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 +++K +K F + D D +G I+++EL + + + + D Sbjct: 35 LKKKSADDVKKVFHILDKDKSGFIEEDELGSILK---GFSSDARDLSAKETKTLMAAGDK 91 Query: 145 NNDGELTLEEF 155 + DG++ +EEF Sbjct: 92 DGDGKIGVEEF 102 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF---IAAVNLIMQEKMEQKLKWYF 97 K + GL +K+ + +V++ D +K GF++ E + + ++ ++ K Sbjct: 27 KKFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLM 86 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 D DG+G I E + Sbjct: 87 AAGDKDGDGKIGVEEFSTLVAE 108 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 21/58 (36%), Gaps = 2/58 (3%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 + + SG E ++L + + + K + D + DG + EF V Sbjct: 50 LDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVA 107 >3PAT-A nrPDB Length = 110 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%) Query: 57 IDQVYNTFDT-NKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 D + D +G + +F A V L + +K FK DAD +G I++ EL Sbjct: 9 ADDIKKALDAVKAEGSFNHKKFFALVGL--KAMSANDVKKVFKAIDADASGFIEEEELKF 66 Query: 116 MFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 + + A + L+ E D + DG++ ++EF Sbjct: 67 VLKSFAA--DGRDLTDAE-TKAFLKAADKDGDGKIGIDEF 103 Score = 43.1 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 33/80 (41%), Gaps = 3/80 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI---MQEKMEQKLKWYF 97 K L GL + + +V+ D + GF++ E + ++ + + K + Sbjct: 28 KKFFALVGLKAMSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFL 87 Query: 98 KLYDADGNGSIDKNELLDMF 117 K D DG+G I +E + Sbjct: 88 KAADKDGDGKIGIDEFETLV 107 Score = 30.0 bits (66), Expect = 0.70, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 18/53 (33%), Gaps = 2/53 (3%) Query: 32 SGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 SG E K +L + + + D + DG + EF V+ Sbjct: 56 SGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEFETLVH 108 >2VRG-A nrPDB Length = 124 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQ---TLSPEEFINLV---FHKIDINNDGEL 150 FK++D DGN +D EL V G + +S +E IN++ D NNDG + Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 151 TLEEFINGMA 160 EF + Sbjct: 115 DYAEFAKSLQ 124 Score = 28.8 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAV 81 ID V D N DG++D+ EF ++ Sbjct: 99 IDGVLRDDDKNNDGYIDYAEFAKSL 123 >4L9M-A nrPDB Length = 559 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 9/61 (14%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 +D V+ +D ++DG++ EF EK+ + F + D D G I ++E+ Sbjct: 427 VDSVFKNYDHDQDGYISQEEF---------EKIAASFPFSFCVMDKDREGLISRDEITAY 477 Query: 117 F 117 F Sbjct: 478 F 478 Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 28/72 (38%), Gaps = 15/72 (20%) Query: 83 LIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKI 142 + + +++ + FK YD D +G I + E + + F + Sbjct: 417 KTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFPFS---------------FCVM 461 Query: 143 DINNDGELTLEE 154 D + +G ++ +E Sbjct: 462 DKDREGLISRDE 473 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 15/32 (46%) Query: 132 EEFINLVFHKIDINNDGELTLEEFINGMAKDQ 163 + ++ VF D + DG ++ EEF A Sbjct: 424 QRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 >1TIZ-A nrPDB Length = 67 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 +V+ FD NKDG + EF ++ + +F+ D DGNG ++ +E Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEF 59 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 K F+ +D + +G + +E ++ +A Q+ + F +ID++ +GEL + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIV------KFFEEIDVDGNGELNAD 57 Query: 154 EFINGMAK 161 EF + + K Sbjct: 58 EFTSCIEK 65 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 18/48 (37%), Gaps = 1/48 (2%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIA 79 G +L EF+ + + + D + +G ++ EF + Sbjct: 15 DGKLSLDEFREVALAFSPYFTQEDIVKF-FEEIDVDGNGELNADEFTS 61 >1NYA-A nrPDB Length = 176 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 32/94 (34%), Gaps = 9/94 (9%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKH-------IDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 G T +F + Q + + D N DG ++ EF A + + Sbjct: 72 DGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWLTAL 131 Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + + F D +GNG + +ELL Sbjct: 132 --GMSKAEAAEAFNQVDTNGNGELSLDELLTAVR 163 Score = 40.0 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 26/69 (37%), Gaps = 3/69 (4%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 + G EF L G+++ +N DTN +G + E + AV Sbjct: 109 GMCDKNADGQINADEFAAWLTALGMSKAEAAEA---FNQVDTNGNGELSLDELLTAVRDF 165 Query: 85 MQEKMEQKL 93 +++ +L Sbjct: 166 HFGRLDVEL 174 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 47/120 (39%), Gaps = 17/120 (14%) Query: 53 ANKHIDQVYNTFDTNKDGFVDFLEF-------IAAVNLIMQEKMEQKLKWYFK-LYD--- 101 A+ + + ++ +D + +G ++ +F A Q LK F L+D Sbjct: 5 ASDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLA 64 Query: 102 ----ADGNGSIDKNELLDMFMAVQALNGQQTLSPE--EFINLVFHKIDINNDGELTLEEF 155 +GS+ + + + + + G+ + + + + D N DG++ +EF Sbjct: 65 KEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEF 124 Score = 36.2 bits (82), Expect = 0.011, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 43/113 (38%), Gaps = 16/113 (14%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK--------LKWYFKLYDADGNGS 107 D + DG + +FI ++ E+ E +K + D + +G Sbjct: 59 LFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQ 118 Query: 108 IDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 I+ +E A+ + F+++D N +GEL+L+E + + Sbjct: 119 INADEFAAWLTALGMSKAEAA--------EAFNQVDTNGNGELSLDELLTAVR 163 Score = 30.4 bits (67), Expect = 0.56, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI---------NLVFHK 141 +LK F +D DGNG++++ + + G+ + E + + + Sbjct: 7 DRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKE 66 Query: 142 IDINNDGELTLEEFINGM 159 + +DG LT E+FI Sbjct: 67 AGVGSDGSLTEEQFIRVT 84 >3A4U-B nrPDB Length = 143 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQ---TLSPEEFINLV---FHKIDINNDGEL 150 FK++D DGN +D EL V G + +S +E IN++ D NNDG + Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 151 TLEEFINGMA 160 EF + Sbjct: 134 DYAEFAKSLQ 143 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAV 81 ID V D N DG++D+ EF ++ Sbjct: 118 IDGVLRDDDKNNDGYIDYAEFAKSL 142 >4OCI-A nrPDB Length = 146 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 53/130 (40%), Gaps = 16/130 (12%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV---DFLEFIAAVNLIMQE 87 G TL+EF++L+ + G+ + + N + V + F + + + + Sbjct: 19 GDGYLTLNEFESLVRVLGVVMETSAIAST------YNSNSKVRGMSYELFTSCFSQLKTK 72 Query: 88 K-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 146 + ++K + D D G I EL + + Q+ ++ +F + I+ Sbjct: 73 SFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITD------LFTFMGIDE 126 Query: 147 DGELTLEEFI 156 G + +++FI Sbjct: 127 QGVVKVDDFI 136 Score = 34.2 bits (77), Expect = 0.040, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 +K + LK F L+D DG+G + NE + + + ++ Sbjct: 2 QKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIAS 46 Score = 31.5 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 28/81 (34%) Query: 35 QTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLK 94 + F + I N D +K GF+ +E ++ I ++++ Sbjct: 57 MSYELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEIT 116 Query: 95 WYFKLYDADGNGSIDKNELLD 115 F D G + ++ ++ Sbjct: 117 DLFTFMGIDEQGVVKVDDFIN 137 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 17/36 (47%) Query: 133 EFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEI 168 E + F D + DG LTL EF + + ++E Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMET 41 >1IJ5-A nrPDB Length = 323 Score = 43.5 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 54/129 (41%), Gaps = 13/129 (10%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 +G + EF+ G ++K+ + D ++ D ++ V F E++ + + Sbjct: 202 NGTLSRKEFREHFVRLGFDKKSVQ--DALFRYADEDESDDVGFSEYV----HLGLCLLVL 255 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 ++ + F +D +G + K E+ + + S + F +D+++ L+ Sbjct: 256 RILYAFADFDK--SGQLSKEEVQKVLE-----DAHIPESARKKFEHQFSVVDVDDSKSLS 308 Query: 152 LEEFINGMA 160 +EF+ + Sbjct: 309 YQEFVMLVL 317 Score = 35.0 bits (79), Expect = 0.025, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 55/152 (36%), Gaps = 21/152 (13%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 + + SG L L+++ + Q++ + + G F + + Sbjct: 99 LEDDASGYNRLRP-----SKPMLSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKYAD 153 Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 146 E LK F + + D G + L+ + + AL F KID N+ Sbjct: 154 TIPEGPLKKLFVMVENDTKGRMSYITLVAVANDLAALVAD------------FRKIDTNS 201 Query: 147 DGELTLEEFINGMAKD----QDLLEIVYKSFD 174 +G L+ +EF + + + + +++ D Sbjct: 202 NGTLSRKEFREHFVRLGFDKKSVQDALFRYAD 233 Score = 31.9 bits (71), Expect = 0.19, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 22/53 (41%) Query: 26 FMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFI 78 F SG + E + +L + + A K + ++ D + + + EF+ Sbjct: 261 FADFDKSGQLSKEEVQKVLEDAHIPESARKKFEHQFSVVDVDDSKSLSYQEFV 313 >6EAZ-A nrPDB Length = 379 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 56/162 (34%), Gaps = 26/162 (16%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 D G + + E++ + ++ + FK+ D DGN I++ E + + + + Sbjct: 95 DLGDKGVISYTEYLFLLTILTKP--HSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQD 152 Query: 125 GQQTLSPEEF-----------INLVF--HKIDINNDGELTLEEFINGMAKDQDLLEIV-- 169 G +T+ E +N + +L +EF M Q ++ + Sbjct: 153 GFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEF 212 Query: 170 ---------YKSFDFSNVLRVICNGKQPDMETDSSKSPDKAG 202 + DF+ L N + D+ + + G Sbjct: 213 LQFSKGLNFMRKEDFAEWLLFFTNTENKDIYWRNVREKLSVG 254 Score = 31.2 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 76 EFIAAVNL-IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 EF AV + QE + L FK++D DG+ + E L + Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKN 337 Score = 30.4 bits (67), Expect = 0.61, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 22/47 (46%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 EFK + + + ++ +D V+ FD + D + EF+ + M Sbjct: 293 EFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRM 339 >3BOW-B nrPDB Length = 184 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 14/117 (11%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + D++ G + F EF N I + + +K +D D +G+I NEL F Sbjct: 61 RSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQG------IYKRFDTDRSGTIGSNELPGAF 114 Query: 118 MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 A Q S ++ D G + + FI+ + + + ++S D Sbjct: 115 EAAGFHLNQHIYSM-----IIRRYSDET--GNMDFDNFISCLVRLDAMFRA-FRSLD 163 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 34/95 (35%), Gaps = 9/95 (9%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 ++ Y+ F + SG +E G + + + + D + +DF Sbjct: 88 KKWQGIYKRFDTDR-SGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGN--MDFDN 144 Query: 77 FIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 FI+ + + + F+ D +G G I N Sbjct: 145 FISCLVRL------DAMFRAFRSLDKNGTGQIQVN 173 >4D1E-A nrPDB Length = 876 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + + F +D NG +D + +++ G+ + + +D N G +T Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFA------RIMTLVDPNGQGTVT 792 Query: 152 LEEFINGMAKD 162 + FI+ M ++ Sbjct: 793 FQSFIDFMTRE 803 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 40/103 (38%), Gaps = 5/103 (4%) Query: 34 LQTLHEFKTLLG-LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK 92 E + L +G+ Q+ +N FD K+G +D +F A + + + E + Sbjct: 716 TINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE 775 Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI 135 L D +G G++ +D A T + E+ I Sbjct: 776 FARIMTLVDPNGQGTVTFQSFIDFMTRETA----DTDTAEQVI 814 >2SAS-A nrPDB Length = 185 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 48/132 (36%), Gaps = 19/132 (14%) Query: 48 GLNQKANKHIDQVYNTF-DTNKDGFVDFLEFIAAVNL---------------IMQEKMEQ 91 GLN + I ++ F D N DG + +F + MQ +E Sbjct: 1 GLNDFQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLED 60 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP---EEFINLVFHKIDINNDG 148 + + D + + + E L M+ A P + I +F +D++ DG Sbjct: 61 EWRDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDG 120 Query: 149 ELTLEEFINGMA 160 + LEEF N Sbjct: 121 IVDLEEFQNYCK 132 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 10/82 (12%) Query: 90 EQKLKWYFKLY-DADGNGSIDKNELLDMFMAVQALNGQQT---------LSPEEFINLVF 139 +QK+K+ F + D + +GSI N+ DM + +N S E+ + Sbjct: 7 KQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLK 66 Query: 140 HKIDINNDGELTLEEFINGMAK 161 + DIN D ++ EE++ K Sbjct: 67 GRADINKDDVVSWEEYLAMWEK 88 >6AGH-A nrPDB Length = 339 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 28/162 (17%), Positives = 53/162 (32%), Gaps = 26/162 (16%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 D G + + E++ + ++ + FK+ D DGN I+K E + + + Sbjct: 92 DLGDKGLISYTEYLFLLTILTKP--HSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQD 149 Query: 125 GQQTLS-------------PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV-- 169 T+ PE L +L +EF M Q ++ + Sbjct: 150 DLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEF 209 Query: 170 ---------YKSFDFSNVLRVICNGKQPDMETDSSKSPDKAG 202 + DF+ L N + D+ + + AG Sbjct: 210 LQFSKGLSFMRKEDFAEWLLFFTNTENKDIYWKNVREKLSAG 251 Score = 31.5 bits (70), Expect = 0.28, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 22/47 (46%) Query: 39 EFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 EFK + + + +N +D V+ FD + D + EF+ + M Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRM 336 Score = 30.4 bits (67), Expect = 0.53, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 76 EFIAAVNL-IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 119 EF AV + QE L FK++D DG+ + E L + Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKN 334 >4YGB-B nrPDB Length = 104 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 85 MQEKMEQKLKW-YFKLYDADGNGSIDKNELLDMFMAVQALNGQQ---TLSPEEFINLV-- 138 M E Q+L+ YFK++D DGN +D EL V G + +S +E IN++ Sbjct: 22 MLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 81 Query: 139 -FHKIDINNDGELTLEEFINGMA 160 D NNDG + EF + Sbjct: 82 VLRDDDKNNDGYIDYAEFAKSLQ 104 Score = 28.1 bits (61), Expect = 2.6, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAV 81 ID V D N DG++D+ EF ++ Sbjct: 79 IDGVLRDDDKNNDGYIDYAEFAKSL 103 >1BU3-A nrPDB Length = 109 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWY 96 +K GL K+ I + + D +K GF++ E F+ + + + + K + Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 97 FKLYDADGNGSIDKNELLDMFMA 119 K D+DG+G+I +E + A Sbjct: 87 LKAGDSDGDGAIGVDEWAALVKA 109 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + K +K F + D D +G I+++EL A G + L+ E D Sbjct: 36 LTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSA--GARALTDAE-TKAFLKAGDS 92 Query: 145 NNDGELTLEEFINGMAK 161 + DG + ++E+ + Sbjct: 93 DGDGAIGVDEWAALVKA 109 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 18/53 (33%), Gaps = 2/53 (3%) Query: 32 SGLQTLHEFKTLLGLQ--GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 SG E K L + G + D++ DG + E+ A V Sbjct: 56 SGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIGVDEWAALVK 108 >2W4G-C nrPDB Length = 145 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 57/146 (39%), Gaps = 13/146 (8%) Query: 18 ETHVWYRTFMMEYPSG--LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF-VDF 74 E + + F++ +G TL + ++ G N + + N + + F Sbjct: 2 EINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITF 61 Query: 75 LEFIAAVNLIMQEKME---QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 EF+ + K + + +++D +GNG++ EL + + + ++ Sbjct: 62 EEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATL-----GEKMTE 116 Query: 132 EEFINLVFHKIDINNDGELTLEEFIN 157 EE L+ + D N G + E F+ Sbjct: 117 EEVEELMKGQEDSN--GCINYEAFVK 140 Score = 31.5 bits (70), Expect = 0.25, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN--NDGEL 150 K F L+D G+ I +++ D+ A+ IN + N ++ Sbjct: 6 FKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAE------INKILGNPSKEEMNAKKI 59 Query: 151 TLEEFINGMAK 161 T EEF+ + Sbjct: 60 TFEEFLPMLQA 70 >3SIA-A nrPDB Length = 220 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 48/114 (42%), Gaps = 16/114 (14%) Query: 19 THVWYRTFMMEYPSGLQTLHEFKTLLGLQ-GLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 + W+ + SG ++E +G G + + + ++ FDT+ +G + F EF Sbjct: 53 IYQWFMGVDRDR-SGTLEINELM--MGQFPGGIRLSPQTALRMMRIFDTDFNGHISFYEF 109 Query: 78 IAAVNLIMQEKMEQKLKWYFKLYDAD---GNGSIDKNELLDMFMAVQALNGQQT 128 +A ++ + L+ + +G+++ +E+L + Q+T Sbjct: 110 MAMYKF---------MELAYNLFVMNARARSGTLEPHEILPALQQLGFYINQRT 154 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 10/77 (12%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 F D D +G+++ NEL + G LSP+ + + D + +G ++ EF+ Sbjct: 57 FMGVDRDRSGTLEINEL-----MMGQFPGGIRLSPQTAL-RMMRIFDTDFNGHISFYEFM 110 Query: 157 NGMAKDQDLLEIVYKSF 173 +E+ Y F Sbjct: 111 AMYK----FMELAYNLF 123 >1RK9-A nrPDB Length = 110 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 +++K +K F + D D +G I+++EL + + + ++ D Sbjct: 36 LKKKSADDVKKVFHMLDKDKSGFIEEDELGFILK---GFSPDARDLSAKETKMLMAAGDK 92 Query: 145 NNDGELTLEEF 155 + DG++ ++EF Sbjct: 93 DGDGKIGVDEF 103 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 36/82 (43%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF---IAAVNLIMQEKMEQKLKWYF 97 K + GL +K+ + +V++ D +K GF++ E + + ++ ++ K Sbjct: 28 KKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLM 87 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 D DG+G I +E + Sbjct: 88 AAGDKDGDGKIGVDEFSTLVAE 109 Score = 30.0 bits (66), Expect = 0.80, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 20/59 (33%), Gaps = 2/59 (3%) Query: 26 FMMEYPSGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 + + SG E +L + + + K + D + DG + EF V Sbjct: 50 MLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVA 108 >1I84-U nrPDB Length = 166 Score = 42.7 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 51/145 (35%), Gaps = 13/145 (8%) Query: 12 KAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 E + F + + G+ + + G N+ +D + Sbjct: 17 SMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEA----S 72 Query: 70 GFVDFLEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQT 128 G ++F F+ ++ E + FK+ D DG GSI K+ L ++ G Sbjct: 73 GPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTT-----GGGR 127 Query: 129 LSPEEFINLVFHKIDINNDGELTLE 153 +PEE I ++ + G + + Sbjct: 128 FTPEE-IKNMWAAFPPDVAGNVDYK 151 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 E + K F + D + +G IDK++L + F A+ LN + E ++ + + Sbjct: 20 DETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN-----EELDAMIKEA--- 71 Query: 146 NDGELTLEEFING 158 G + F+ Sbjct: 72 -SGPINFTVFLTM 83 Score = 26.1 bits (56), Expect = 9.6, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 36/101 (35%), Gaps = 2/101 (1%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 M++ SG F T+ G + I + D + G + F+ + Sbjct: 67 MIKEASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIK-KSFLEELLTTGG 125 Query: 87 EK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ 126 + +++K + + D G++D + + + G+ Sbjct: 126 GRFTPEEIKNMWAAFPPDVAGNVDYKNICYVITHGEDAEGE 166 >1O1A-B nrPDB Length = 145 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 51/143 (35%), Gaps = 13/143 (9%) Query: 14 VPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGF 71 E + F + + G+ + + G N+ +D + G Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEA----SGP 56 Query: 72 VDFLEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 ++F F+ ++ E + FK+ D DG GSI K+ L ++ G + Sbjct: 57 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTT-----GGGRFT 111 Query: 131 PEEFINLVFHKIDINNDGELTLE 153 PEE I ++ + G + + Sbjct: 112 PEE-IKNMWAAFPPDVAGNVDYK 133 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 E + K F + D + +G IDK++L + F A+ LN + E ++ + + Sbjct: 2 DETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN-----EELDAMIKEA--- 53 Query: 146 NDGELTLEEFING 158 G + F+ Sbjct: 54 -SGPINFTVFLTM 65 >1NP8-A nrPDB Length = 159 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 14/117 (11%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + D++ G + F EF N I + + +K +D D +G+I NEL F Sbjct: 57 RSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQG------IYKRFDTDRSGTIGSNELPGAF 110 Query: 118 MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFD 174 A Q S ++ D G + + FI+ + + + ++S D Sbjct: 111 EAAGFHLNQHIYSM-----IIRRYSDET--GNMDFDNFISCLVRLDAMFRA-FRSLD 159 >1G33-A nrPDB Length = 73 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 K +K F + D D +G I+++EL + + + + D + D Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILK---GFSSDARDLSAKETKTLMAAGDKDGD 58 Query: 148 GELTLEEF 155 G++ +EEF Sbjct: 59 GKIGVEEF 66 Score = 34.6 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEF---IAAVNLIMQEKMEQKLKWYFKLYDADGNGS 107 K+ + +V++ D +K GF++ E + + ++ ++ K D DG+G Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGK 60 Query: 108 IDKNELLDMFMA 119 I E + Sbjct: 61 IGVEEFSTLVAE 72 Score = 28.5 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 21/58 (36%), Gaps = 2/58 (3%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVN 82 + + SG E ++L + + + K + D + DG + EF V Sbjct: 14 LDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVA 71 >2PMY-A nrPDB Length = 91 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 8/67 (11%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 +L+ F DA+ +G +++ E + ++ VF ++D + DG +T Sbjct: 28 RLRSVFAACDANRSGRLEREEFRALCTELRVRPAD--------AEAVFQRLDADRDGAIT 79 Query: 152 LEEFING 158 +EF G Sbjct: 80 FQEFARG 86 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 28/68 (41%), Gaps = 2/68 (2%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSID 109 + + + V+ D N+ G ++ EF A + + + F+ DAD +G+I Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAE--AVFQRLDADRDGAIT 79 Query: 110 KNELLDMF 117 E F Sbjct: 80 FQEFARGF 87 Score = 33.8 bits (76), Expect = 0.055, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 19/50 (38%), Gaps = 3/50 (6%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 SG EF+ L + + V+ D ++DG + F EF Sbjct: 41 SGRLEREEFRALCTELRVRP---ADAEAVFQRLDADRDGAITFQEFARGF 87 >2LUC-A nrPDB Length = 105 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 82 NLIMQEKMEQKLKWYFKLY-DADG-NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVF 139 + E+ + L F+ Y DG N ++ K E L A + P ++ + Sbjct: 6 SPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDP-GVLDRMM 64 Query: 140 HKIDINNDGELTLEEFINGM 159 K+D N+DG+L EF+N + Sbjct: 65 KKLDTNSDGQLDFSEFLNLI 84 Score = 35.4 bits (80), Expect = 0.020, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 4/52 (7%) Query: 34 LQTLHEFKTLL----GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 + EF + + NQK +D++ DTN DG +DF EF+ + Sbjct: 33 TLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLI 84 >2MBX-A nrPDB Length = 109 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 G D F V L + + +K F++ D D + ++++EL +Q + Sbjct: 23 GSFDHKAFFTKVGLAAKSPAD--IKKVFEIIDQDKSDFVEEDELKLF---LQNFSAGARA 77 Query: 130 SPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 + + D + DG++ ++EF + Sbjct: 78 LSDAETKVFLKAGDSDGDGKIGVDEFGAMIKA 109 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 3/82 (3%) Query: 41 KTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE---FIAAVNLIMQEKMEQKLKWYF 97 K GL K+ I +V+ D +K FV+ E F+ + + + + K + Sbjct: 28 KAFFTKVGLAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFL 87 Query: 98 KLYDADGNGSIDKNELLDMFMA 119 K D+DG+G I +E M A Sbjct: 88 KAGDSDGDGKIGVDEFGAMIKA 109 >6AGI-A nrPDB Length = 382 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 46/127 (36%), Gaps = 11/127 (8%) Query: 34 LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKL 93 + +F +L + + ++ V + K + F EF + + + Sbjct: 255 TISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG--ITFDEFRSFFQFLNNL---EDF 309 Query: 94 KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 +Y+ + SI ++E L L +N VF D++ D +L+ + Sbjct: 310 AIALNMYNF-ASRSIGQDEFKRAVYVATGLKFSPHL-----VNTVFKIFDVDKDDQLSYK 363 Query: 154 EFINGMA 160 EFI M Sbjct: 364 EFIGIMK 370 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 G + + E++ + ++ + + F ++D DGN +DK E L + + N ++ + Sbjct: 86 GVISYTEYLFLLCILTKP--HAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREI 143 Query: 130 SPEEFINLVFH 140 +E + Sbjct: 144 KGDEEKRAMLR 154 Score = 34.2 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 41/99 (41%), Gaps = 14/99 (14%) Query: 7 IAGDQKAVPTQETHV--------WY---RTFMMEYPSGLQTLHEFKTLLGLQGLNQKANK 55 +A K++ QE + W + F G+ + E+ LL + K + Sbjct: 49 VAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCIL---TKPHA 105 Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLK 94 +N FDT+ + VD EF+ + ++ ++++K Sbjct: 106 GFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIK 144 >3JBH-C nrPDB Length = 156 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 22/136 (16%), Positives = 41/136 (30%), Gaps = 11/136 (8%) Query: 31 PSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-- 88 G + LL D + + EF+ + I +EK Sbjct: 23 GEGKIDARDLGDLLRSLDCKPTLAMVKKN--GGSDKRGEKKLTLEEFLPIFSQIKKEKEV 80 Query: 89 -MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 + K+YD NG++ EL + +++ + D ++D Sbjct: 81 GTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIEC------EEIMRVCDEDDD 134 Query: 148 GELTLEEFINGMAKDQ 163 G L E F+ + Sbjct: 135 GFLKYEPFVKTIIAGP 150 Score = 31.9 bits (71), Expect = 0.20, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 8/100 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 +K + +F++YD +G G ID +L D+ ++ + D + +L Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKN-------GGSDKRGEKKL 62 Query: 151 TLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDM 190 TLEEF+ ++ + E+ DF L+V + M Sbjct: 63 TLEEFLPIFSQIKKEKEVGT-LEDFMEGLKVYDKAENGTM 101 >4I5K-A nrPDB Length = 285 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 51/122 (41%), Gaps = 8/122 (6%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKD-----GFVDFLEFIAAVNLIMQEKMEQKLKWYFK 98 L +++ I+++++ T G + + +F+ + ++ ++++F+ Sbjct: 138 LSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFR 197 Query: 99 LYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN---DGELTLEEF 155 D DG+G + EL + + P F +L+ +D+ DG++TL + Sbjct: 198 CMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDL 257 Query: 156 IN 157 Sbjct: 258 KR 259 Score = 27.7 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 52/154 (33%), Gaps = 20/154 (12%) Query: 32 SGLQTLHE-----FKTLLGLQGLNQKANKHIDQV-----------YNTFDTNKDGFVDFL 75 SG T E F L L + N+ D + DT+ D ++ Sbjct: 77 SGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQA 136 Query: 76 EFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI 135 + + ++ +++ F G +I K + V L ++ I Sbjct: 137 DLSRYNDQASSSRIIERI---FSGAVTRGK-TIQKEGRMSYADFVWFLISEEDKRNPTSI 192 Query: 136 NLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 169 F +D++ DG L++ E + + +E + Sbjct: 193 EYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAM 226 >3I5H-B nrPDB Length = 153 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 43/116 (37%), Gaps = 7/116 (6%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + T + + G + + K + G + ++ + G ++F Sbjct: 14 QMQELKEAF-TMIDQDRDGFIGMEDLKDMFSSLG-RVPPDDELNAMLKEC----PGQLNF 67 Query: 75 LEFIAAVNLIMQEKM-EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTL 129 F+ + E L+ F ++D DG G I ++ L D+ + ++ + Sbjct: 68 TAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGDNFSKEEI 123 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 10/75 (13%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + + ++ Q+LK F + D D +G I +L DMF ++ + P++ +N + + Sbjct: 7 RVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLG------RVPPDDELNAMLKE 60 Query: 142 IDINNDGELTLEEFI 156 G+L F+ Sbjct: 61 C----PGQLNFTAFL 71 >2I18-A nrPDB Length = 64 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 10/68 (14%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 LK +KL D DG+G + K E+ F E+ V D N DG +TL Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFK---------KHGIEKVAEQVMK-ADANGDGYITL 56 Query: 153 EEFINGMA 160 EEF+ Sbjct: 57 EEFLEFSL 64 Score = 33.5 bits (75), Expect = 0.066, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM 116 +Y D + DG + E + EK+ +++ DA+G+G I E L+ Sbjct: 10 LYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKA----DANGDGYITLEEFLEF 62 Score = 27.3 bits (59), Expect = 4.9, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 6/62 (9%) Query: 19 THVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFI 78 V Y+ ++ G T E + G+ + A + + D N DG++ EF+ Sbjct: 7 LKVLYKLMDVD-GDGKLTKEEVTSFFKKHGIEKVAEQVMKA-----DANGDGYITLEEFL 60 Query: 79 AA 80 Sbjct: 61 EF 62 Score = 26.9 bits (58), Expect = 5.7, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 17/28 (60%) Query: 135 INLVFHKIDINNDGELTLEEFINGMAKD 162 + +++ +D++ DG+LT EE + K Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKH 34 >3I5I-C nrPDB Length = 159 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 31/85 (36%), Gaps = 8/85 (9%) Query: 81 VNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFH 140 ++ + FK +D +G G I E+ ++ + E+ N +F Sbjct: 75 MSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGERIT------EDQCNDIFT 128 Query: 141 KIDI--NNDGELTLEEFINGMAKDQ 163 DI + DG + E+ + + Sbjct: 129 FCDIREDIDGNIKYEDLMKKVMAGP 153 >1SJJ-A nrPDB Length = 863 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 36/96 (37%), Gaps = 9/96 (9%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + + F +D G +D + +++ G+ + + +D N G +T Sbjct: 726 EFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFA------RIMSIVDPNRMGVVT 779 Query: 152 LEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQ 187 + FI+ M+++ + + +++ K Sbjct: 780 FQAFIDFMSRETADTDTADQVM---ASFKILAGDKN 812 Score = 35.4 bits (80), Expect = 0.018, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 45/131 (34%), Gaps = 7/131 (5%) Query: 34 LQTLHEFKTLLG-LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK 92 E + L +G++Q+ +N FD K G +D +F A + + E + Sbjct: 703 TINEVENQILTRDAKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAE 762 Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTL 152 + D + G + +D A + + + D N +T+ Sbjct: 763 FARIMSIVDPNRMGVVTFQAFIDFMSRETA---DTDTADQVMASFKILAGDKN---YITV 816 Query: 153 EEFINGMAKDQ 163 +E + DQ Sbjct: 817 DELRRELPPDQ 827 >3A8R-A nrPDB Length = 179 Score = 39.6 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 23/147 (15%), Positives = 55/147 (37%), Gaps = 11/147 (7%) Query: 24 RTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVD----FLEFIA 79 + F G+ F +G+ G ++ A + D + K G V E Sbjct: 32 KRFNQLQVDGVLLRSRFGKCIGMDGSDEFAVQMFDSLAR-----KRGIVKQVLTKDELKD 86 Query: 80 AVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDM--FMAVQALNGQQTLSPEEFINL 137 + + + +L+ +F + D + +G + E+ ++ A + +E+ L Sbjct: 87 FYEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKERADEYTAL 146 Query: 138 VFHKIDINNDGELTLEEFINGMAKDQD 164 + ++D N G + +E+ + + Sbjct: 147 IMEELDPTNLGYIEMEDLEALLLQSPS 173 >5H53-B nrPDB Length = 146 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 47/140 (33%), Gaps = 12/140 (8%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + G+ + + G N+ +D + G ++F Sbjct: 3 QIQEFKEAFTVIDQNRD-GIIDKEDLRDTFAAMGRLNVKNEELDAMMKEA----SGPINF 57 Query: 75 LEFIAAVNLIMQE-KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 F+ ++ E + FK+ D +G G+I K L ++ L Q +E Sbjct: 58 TVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEEL------LITQCDRFSQE 111 Query: 134 FINLVFHKIDINNDGELTLE 153 I ++ + G + + Sbjct: 112 EIKNMWAAFSPDVGGNVDYK 131 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 9/72 (12%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 146 + Q+ K F + D + +G IDK +L D F A+ LN + E ++ + + Sbjct: 1 QTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKN-----EELDAMMKEA---- 51 Query: 147 DGELTLEEFING 158 G + F+ Sbjct: 52 SGPINFTVFLTM 63 Score = 33.1 bits (74), Expect = 0.098, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 39/107 (36%), Gaps = 9/107 (8%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDK 110 Q + + + D N+DG +D + + + ++ + + +G I+ Sbjct: 1 QTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMM---KEASGPINF 57 Query: 111 NELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFIN 157 L MF + PE+ I F +D G + ++F+ Sbjct: 58 TVFLTMFGE-----KLKGADPEDVITGAFKVLDPEGKGTI-KKQFLE 98 >6DS2-B nrPDB Length = 114 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 27/55 (49%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 ++++ E ++ ++ E+ I + +D N D +L+ EEFI MA+ Sbjct: 31 TLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 Score = 34.6 bits (78), Expect = 0.031, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 25/67 (37%), Gaps = 6/67 (8%) Query: 34 LQTLHEFKTLLGLQGLN-----QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK 88 EFK L+ N K K I+ + DTN D + F EFI + + Sbjct: 31 TLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARL-TWA 89 Query: 89 MEQKLKW 95 +K+ Sbjct: 90 SHEKMHE 96 >2M1U-A nrPDB Length = 93 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 27/78 (34%), Gaps = 9/78 (11%) Query: 82 NLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK 141 + + EK + L F +D D +G + E + + E I F Sbjct: 19 SHMSDEKTQ--LIEAFYNFDGDYDGFVSVEEFRGIIRDGLPM-------TEAEITEFFEA 69 Query: 142 IDINNDGELTLEEFINGM 159 D NN G + + F + Sbjct: 70 ADPNNTGFIDYKAFAAML 87 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 52 KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKN 111 + + + FD + DGFV EF + + E ++ +F+ D + G ID Sbjct: 23 DEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGL-PMTEAEITEFFEAADPNNTGFIDYK 81 Query: 112 ELLDMFMAV 120 M +V Sbjct: 82 AFAAMLYSV 90 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 26/66 (39%), Gaps = 3/66 (4%) Query: 16 TQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFL 75 + + F +Y G ++ EF+ ++ I + + D N GF+D+ Sbjct: 25 KTQLIEAFYNFDGDYD-GFVSVEEFRGIIR--DGLPMTEAEITEFFEAADPNNTGFIDYK 81 Query: 76 EFIAAV 81 F A + Sbjct: 82 AFAAML 87 >1NSH-A nrPDB Length = 101 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 82 NLIMQEKMEQKLKWYFKLY-DADG-NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVF 139 E+ + L F+ Y DG + ++ K E L A + P ++ + Sbjct: 2 RPTETERCIESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDP-GVLDRMM 60 Query: 140 HKIDINNDGELTLEEFINGM 159 K+D+N+DG+L +EF+N + Sbjct: 61 KKLDLNSDGQLDFQEFLNLI 80 Score = 33.8 bits (76), Expect = 0.048, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 28 MEYPSGLQTLHEFKTLL----GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 + S + EF + + NQK +D++ D N DG +DF EF+ + Sbjct: 23 KDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLI 80 >1BOD-A nrPDB Length = 74 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Query: 88 KMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINND 147 K ++LK F+ YD +G+G + + L ++ +F ++D N D Sbjct: 2 KSPEELKGIFEKYDKEGDG----QLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGD 57 Query: 148 GELTLEEFINGMAKD 162 GE++ EEF + K Sbjct: 58 GEVSFEEFQVLVKKI 72 Score = 28.1 bits (61), Expect = 2.9, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 +D+++ D N DG V F EF V I Q Sbjct: 45 LDELFEELDKNGDGEVSFEEFQVLVKKISQ 74 Score = 27.7 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 11/81 (13%), Positives = 28/81 (34%), Gaps = 20/81 (24%) Query: 51 QKANKHIDQVYNTFDTNKDGFV-----------DFLEFIAAVNLIMQEKMEQKLKWYFKL 99 K+ + + ++ +D DG + +F + ++ L F+ Sbjct: 1 MKSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMST---------LDELFEE 51 Query: 100 YDADGNGSIDKNELLDMFMAV 120 D +G+G + E + + Sbjct: 52 LDKNGDGEVSFEEFQVLVKKI 72 >1QLS-A nrPDB Length = 99 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Query: 104 GNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 N I K E L A Q P ++ + K+D+++DG+L +EF+N + Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDP-GVLDRMMKKLDLDSDGQLDFQEFLNLI 82 Score = 33.5 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 4/51 (7%) Query: 35 QTLHEFKTLL----GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAV 81 + EF + NQK +D++ D + DG +DF EF+ + Sbjct: 32 ISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLI 82 >1CB1-A nrPDB Length = 78 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 85 MQEKMEQKLKWYFKLYD-ADGN-GSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKI 142 +K +LK F+ Y +G+ + K EL + A + + ++ +F ++ Sbjct: 1 SAQKSPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRT----LDDLFQEL 56 Query: 143 DINNDGELTLEEFINGMAKD 162 D N DGE++ EEF + K Sbjct: 57 DKNGDGEVSFEEFQVLVKKI 76 Score = 35.0 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 1/54 (1%) Query: 34 LQTLHEFKTLLGLQGLNQ-KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 + E K L+ + + K + +D ++ D N DG V F EF V I Q Sbjct: 25 QLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFEEFQVLVKKISQ 78 >3H4S-E nrPDB Length = 135 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%) Query: 34 LQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKL 93 L T + G+ G+ + + + D + DG ++ EF + + E ME Sbjct: 56 LITAESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMMEDAE 115 Query: 94 KW 95 W Sbjct: 116 TW 117 Score = 31.5 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 36/96 (37%), Gaps = 7/96 (7%) Query: 74 FLEFIAAVNLIMQ-EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 + + + + M E+ +L F L I L + G + +S E Sbjct: 22 YEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESLRR----NSGILGIEGMSKE 77 Query: 133 EFINLVFHKIDINNDGELTLEEFINGMAK-DQDLLE 167 + + + D++ DG L EF M + +++E Sbjct: 78 D-AQGMVREGDLDGDGALNQTEFCVLMVRLSPEMME 112 >1ZFS-A nrPDB Length = 93 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 + K EL D+ + + + ++ + ++D N DGE+ +EF+ Sbjct: 27 KLSKKELKDLL-QTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFV 75 Score = 35.0 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 40 FKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 +T L QK +D++ D N DG VDF EF+ V + Sbjct: 37 LQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAAL 81 >2KGR-A nrPDB Length = 111 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 8/69 (11%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 K + F +D +G + + + Q+ P+ + +++ DI+ DG+LT Sbjct: 15 KYRQLFNSHDKTMSGHLTGPQARTIL--------MQSSLPQAQLASIWNLSDIDQDGKLT 66 Query: 152 LEEFINGMA 160 EEFI M Sbjct: 67 AEEFILAMH 75 Score = 29.6 bits (65), Expect = 0.88, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 4/75 (5%) Query: 58 DQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ-KLKWYFKLYDADGNGSIDKNELLDM 116 Q++N+ D G + + A ++MQ + Q +L + L D D +G + E + Sbjct: 17 RQLFNSHDKTMSGHLTGPQ---ARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILA 73 Query: 117 FMAVQALNGQQTLSP 131 + Q L P Sbjct: 74 MHLIDVAMSGQPLPP 88 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 SG T + +T+L L + ++N D ++DG + EFI A++LI Sbjct: 28 SGHLTGPQARTILMQSSL---PQAQLASIWNLSDIDQDGKLTAEEFILAMHLI 77 >2FCE-A nrPDB Length = 70 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 35/71 (49%), Gaps = 6/71 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 + F+++D + G + +L M + + L+ E ++ + ++++++GE+ Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTGL-----GEKLTDAE-VDELLKGVEVDSNGEI 58 Query: 151 TLEEFINGMAK 161 ++FI + + Sbjct: 59 DYKKFIEDVLR 69 Score = 27.7 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 13 AVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV 72 T++ ++ F E +G ++ + + +L G + +D++ + + +G + Sbjct: 1 KAKTEDFVKAFQVFDKE-STGKVSVGDLRYMLTGLGEKLT-DAEVDELLKGVEVDSNGEI 58 Query: 73 DFLEFIA 79 D+ +FI Sbjct: 59 DYKKFIE 65 Score = 26.9 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 23/55 (41%) Query: 61 YNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLD 115 + FD G V + + + ++ + ++ K + D NG ID + ++ Sbjct: 11 FQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIE 65 >2WCE-A nrPDB Length = 95 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 ++ K EL + A N + + + I+ +F +D N D ++ +EFI+ + Sbjct: 30 TLSKGELKQLLTKELA-NTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMV 81 Score = 33.8 bits (76), Expect = 0.055, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%) Query: 34 LQTLHEFKTLLGLQGLNQ----KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 + E K LL + N K ID+++ D N+D VDF EFI+ V + ++ Sbjct: 30 TLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVAIALK 86 >5TBY-E nrPDB Length = 166 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 ++ Q+ K F + D + +G IDKN+L D F A+ +N + E I+ + + Sbjct: 22 EQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKN-----EEIDEMIKEA--- 73 Query: 146 NDGELTLEEFING 158 G + F+ Sbjct: 74 -PGPINFTVFLTM 85 Score = 34.2 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 32/93 (34%), Gaps = 1/93 (1%) Query: 26 FMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 + E P G F T+ G + + I + FD G + + Sbjct: 69 MIKEAP-GPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQA 127 Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFM 118 + ++++ F + D G++D L+ + Sbjct: 128 ERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIIT 160 Score = 32.3 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 59/154 (38%), Gaps = 23/154 (14%) Query: 50 NQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME-QKLKWYFKLYDADGNGSI 108 Q + + + D N+DGF+D + + + ++ +++ K + G I Sbjct: 22 EQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIK----EAPGPI 77 Query: 109 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK-----DQ 163 + L MF + PEE I F D G L + + + Sbjct: 78 NFTVFLTMFGE-----KLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSK 132 Query: 164 DLLEIVYKSF--------DFSNVLRVICNGKQPD 189 + ++ ++ +F D+ N++ +I +G++ D Sbjct: 133 EEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD 166 >4MSP-A nrPDB Length = 200 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 33/92 (35%), Gaps = 2/92 (2%) Query: 66 TNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 G + + +++ + + F+ D + + + K+E+ +G Sbjct: 102 KEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHG 161 Query: 126 QQTLSP--EEFINLVFHKIDINNDGELTLEEF 155 + + +F K D + DG ++ EF Sbjct: 162 AVVNESHHDALVEDIFDKEDEDKDGFISAREF 193 Score = 28.5 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Query: 37 LHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEF 77 EF+ + + + ++ +++ D +KDGF+ EF Sbjct: 154 KKEFEKHGAVVNESHH-DALVEDIFDKEDEDKDGFISAREF 193 >1Q80-A nrPDB Length = 174 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 28/140 (20%), Positives = 53/140 (37%), Gaps = 23/140 (16%) Query: 32 SGLQTLHEFKTLLGLQGLNQKANKH-----IDQVYNTFDTN-----KDGFVDFLEFIAAV 81 G T +F+++ + +D + +D +D FI ++ Sbjct: 20 DGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVAGGKGIDETTFINSM 79 Query: 82 NLIMQEK-----MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 +++ +E L +F+ D + + +I ++E F + S Sbjct: 80 KEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYGIFFGMLGLDKTMAPAS------ 133 Query: 137 LVFHKIDINNDGELTLEEFI 156 F ID NNDG L+LEEF+ Sbjct: 134 --FDAIDTNNDGLLSLEEFV 151 Score = 34.6 bits (78), Expect = 0.030, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 22/50 (44%), Gaps = 3/50 (6%) Query: 35 QTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 + E+ G+ GL++ ++ DTN DG + EF+ A + Sbjct: 111 ISRDEYGIFFGMLGLDKTMAP---ASFDAIDTNNDGLLSLEEFVIAGSDF 157 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 21/48 (43%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV 138 QK+K YF D D +G+I + + M + + + ++ + Sbjct: 6 QKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSL 53 >4I5L-B nrPDB Length = 413 Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 K+G + + +F+ + +K ++++F+ D DG+G++ EL + Sbjct: 249 KEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSM 308 Query: 128 TLSPEEFINLVFHKIDINN---DGELTLEEFIN 157 + F + + +D+ +G++TL++ Sbjct: 309 AIEALPFQDCLCQMLDLVKPRTEGKITLQDLKR 341 >2OS8-B nrPDB Length = 157 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 28/52 (53%) Query: 79 AAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 + V + +K Q++K F + D + +G ID N+L +MF ++ + L+ Sbjct: 7 SGVLTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELT 58 Score = 32.3 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 43/108 (39%), Gaps = 9/108 (8%) Query: 46 LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGN 105 L L QK + + + + D N+DGF+D + + + + +++L K + Sbjct: 10 LTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLK----EAP 65 Query: 106 GSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 G ++ L +F + EE I F D + +L +E Sbjct: 66 GPLNFTMFLSIFS-----DKLSGTDSEETIRNAFGMFDELDTKKLNIE 108 >4MEW-A nrPDB Length = 356 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 K+G + + +F+ + +K ++++F+ D DG+G++ EL + Sbjct: 241 KEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSM 300 Query: 128 TLSPEEFINLVFHKIDINN---DGELTLEEFIN 157 + F + + +D+ +G++TL++ Sbjct: 301 AIEALPFQDCLCQMLDLVKPRTEGKITLQDLKR 333 >3TS5-B nrPDB Length = 161 Score = 36.5 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 27/46 (58%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 + +K+ Q++K F + D + +G ID N+L +MF ++ + L+ Sbjct: 17 LPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELT 62 Score = 31.2 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 9/103 (8%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDK 110 QK + + + + D N+DGF+D + + + + +++L K + G ++ Sbjct: 19 QKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLK----EAPGPLNF 74 Query: 111 NELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 L +F + EE I F D + +L +E Sbjct: 75 TMFLSIFS-----DKLSGTDSEETIRNAFGMFDELDTKKLNIE 112 >2L50-A nrPDB Length = 102 Score = 36.2 bits (82), Expect = 0.011, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 I K+ +M T + + + + +D N+DG ++ +E+ Sbjct: 31 KISKSSFREMLQKELNHMLSDTGNR-KAADKLIQNLDANHDGRISFDEY 78 Score = 27.3 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 7/21 (33%), Positives = 11/21 (52%) Query: 57 IDQVYNTFDTNKDGFVDFLEF 77 D++ D N DG + F E+ Sbjct: 58 ADKLIQNLDANHDGRISFDEY 78 >2L0P-A nrPDB Length = 94 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 23/50 (46%), Gaps = 1/50 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 + K EL ++ + + ++ V ++D N DGE+ +E++ Sbjct: 28 KLSKKELKELL-QTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYV 76 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 4/54 (7%) Query: 35 QTLHEFKTLLGL----QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 + E K LL QK +D+V D N DG VDF E++ V + Sbjct: 29 LSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAAL 82 >3DTP-E nrPDB Length = 196 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 Q+ K F+L D D +G I KN++ F ++ L +Q L Sbjct: 57 QEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDS 97 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 35/111 (31%), Gaps = 6/111 (5%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + + E P G F T+ G + I +N FD DG Sbjct: 91 TEQEL----DSMVAEAP-GPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKE 144 Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNG 125 ++ ++ + ++ DGNG ID + + G Sbjct: 145 ETLKRSLTTWGEKFSQDEVDQALSEAPIDGNGLIDIKKFAQILTKGAKEEG 195 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 20/145 (13%), Positives = 47/145 (32%), Gaps = 40/145 (27%) Query: 50 NQKANKHIDQVYNTFDTNKDGF--------------------------------VDFLEF 77 Q + + + D +KDGF ++F F Sbjct: 52 TQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAEAPGPINFTMF 111 Query: 78 IAAVNLIMQEKMEQK-LKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFIN 136 + + E+ + F L+D +G+G + L +L ++ ++ Sbjct: 112 LTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKR------SLTTWGEKFSQDEVD 164 Query: 137 LVFHKIDINNDGELTLEEFINGMAK 161 + I+ +G + +++F + K Sbjct: 165 QALSEAPIDGNGLIDIKKFAQILTK 189 >2MJW-B nrPDB Length = 94 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 22/57 (38%), Gaps = 4/57 (7%) Query: 34 LQTLHEFKTLLGL----QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 T E K L+ + K +D++ D N D VDF EFI V I Sbjct: 27 TLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAITS 83 Score = 35.0 bits (79), Expect = 0.025, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 ++ K EL + + Q+ ++ ++ + +D N D ++ EFI +A Sbjct: 27 TLTKGELKVLME-KELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAITS 83 >4AOM-A nrPDB Length = 146 Score = 35.4 bits (80), Expect = 0.018, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 35/85 (41%), Gaps = 9/85 (10%) Query: 74 FLEFIAAVNLI-MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 + +++ +++ + ++L F +D + G + K+++ ++ L+ + Sbjct: 66 YEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTW-----GDALTDQ 120 Query: 133 EFINLVFHKIDINNDGELTLEEFIN 157 E I+ + +N + + F Sbjct: 121 EAIDALNAFSSEDN---IDYKLFCE 142 >5W1A-B nrPDB Length = 155 Score = 35.4 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 53/138 (38%), Gaps = 13/138 (9%) Query: 35 QTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME---Q 91 + L LN I+++ T N+ + EF+ + + +EK + + Sbjct: 26 IDAVDLGDALRALNLNPTL-ALIEKLGGTKKRNEK-KIKLDEFLPIYSQVKKEKEQGCYE 83 Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHK-IDINND-GE 149 KLYD + NG++ EL +A+ +E + +F +D +D G Sbjct: 84 DFIECLKLYDKEENGTMLLAELQHALLALG------ESLDDEQVETLFADCMDPEDDEGF 137 Query: 150 LTLEEFINGMAKDQDLLE 167 + F+ M D L+ Sbjct: 138 IPYSPFLARMCDRPDQLK 155 >4NSC-A nrPDB Length = 401 Score = 35.0 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 30/83 (36%) Query: 103 DGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKD 162 +G+ E + + +P+ + F D+N DGE+ +EEF + Sbjct: 116 EGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSII 175 Query: 163 QDLLEIVYKSFDFSNVLRVICNG 185 + + + D + +G Sbjct: 176 RSQTSMGMRHRDRPTTGNTLKSG 198 Score = 31.2 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 34/87 (39%), Gaps = 8/87 (9%) Query: 3 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 +GK I+ +++ + F GL + ++ L + ++ + + Sbjct: 102 DGKKISQEREKFADEG-----SIFYTLGECGLISFSDYIFLTTVL---STPQRNFEIAFK 153 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKM 89 FD N DG VD EF ++I + Sbjct: 154 MFDLNGDGEVDMEEFEQVQSIIRSQTS 180 Score = 30.4 bits (67), Expect = 0.61, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDF 175 + ++VF D + +GEL+ +EF++ M Q L+ + K D Sbjct: 334 SDHVCDVVFALFDCDGNGELSNKEFVSIMK--QRLMRGLEKPKDM 376 Score = 30.0 bits (66), Expect = 0.80, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSP 131 F L+D DGNG + E + + + + G + Sbjct: 342 FALFDCDGNGELSNKEFVSIMKQ-RLMRGLEKPKD 375 Score = 28.8 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 23/57 (40%) Query: 35 QTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQ 91 + + + ++ D V+ FD + +G + EF++ + + +E+ Sbjct: 316 LDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEK 372 >6D1W-A nrPDB Length = 740 Score = 34.6 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 G ++F E + + + +++ F YD DG+ + ++E M ++ Sbjct: 680 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDL 737 Query: 128 TLS 130 L Sbjct: 738 DLD 740 >5MKE-A nrPDB Length = 968 Score = 34.6 bits (78), Expect = 0.033, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 G ++F E + + + +++ F YD DG+ + ++E M ++ Sbjct: 732 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDL 789 Query: 128 TLS 130 L Sbjct: 790 DLD 792 >1KQV-A nrPDB Length = 79 Score = 34.6 bits (78), Expect = 0.035, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 18/28 (64%) Query: 135 INLVFHKIDINNDGELTLEEFINGMAKD 162 ++ +F ++D N DGE++ EEF + K Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKI 77 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 57 IDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 86 +D+++ D N DG V F EF V I Q Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKISQ 79 Score = 26.1 bits (56), Expect = 9.7, Method: Composition-based stats. Identities = 6/28 (21%), Positives = 12/28 (42%) Query: 93 LKWYFKLYDADGNGSIDKNELLDMFMAV 120 L F+ D +G+G + E + + Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKI 77 >5CSF-A nrPDB Length = 95 Score = 34.2 bits (77), Expect = 0.036, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 + K+EL ++ + + + + +E ++ V +D + DGE +EF+ + Sbjct: 30 KLKKSELKELINNELS-HFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFV 81 Score = 31.5 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 22/47 (46%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 L K + +D+V T D + DG DF EF+A V ++ E Sbjct: 44 LSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHE 90 >2KHN-A nrPDB Length = 121 Score = 34.2 bits (77), Expect = 0.038, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 4/79 (5%) Query: 7 IAGDQKAVPTQETHVWYRTFMMEYP-SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFD 65 + D A+ +E + F P SG T + + + + Q++ D Sbjct: 20 GSLDTWAITVEERAKHDQQFHSLKPISGFITGDQARNF---FFQSGLPQPVLAQIWALAD 76 Query: 66 TNKDGFVDFLEFIAAVNLI 84 N DG +D +EF A+ LI Sbjct: 77 MNNDGRMDQVEFSIAMKLI 95 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 27/63 (42%), Gaps = 8/63 (12%) Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQD 164 +G I ++ + F Q+ P+ + ++ D+NNDG + EF M + Sbjct: 46 SGFITGDQARNFF--------FQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKL 97 Query: 165 LLE 167 L+ Sbjct: 98 KLQ 100 >5HYD-A nrPDB Length = 99 Score = 34.2 bits (77), Expect = 0.041, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 19 THVWYRTFMMEYPSGLQTLHEFKTLLGL----QGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +++R E + E K LL QK + +D++ D NKD VDF Sbjct: 13 IRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDF 72 Query: 75 LEFIAAVNLI 84 EF+ V + Sbjct: 73 NEFVVMVAAL 82 Score = 33.1 bits (74), Expect = 0.086, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 15/29 (51%) Query: 133 EFINLVFHKIDINNDGELTLEEFINGMAK 161 + ++ + +D N D E+ EF+ +A Sbjct: 53 QLVDKIVQDLDANKDNEVDFNEFVVMVAA 81 >2JXC-A nrPDB Length = 100 Score = 34.2 bits (77), Expect = 0.044, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 25/55 (45%), Gaps = 8/55 (14%) Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 159 NG + +++ + + + P + + V+ DI++DG L +EF M Sbjct: 28 NGFLSGDKVKPVLLN--------SKLPVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >2VTG-A nrPDB Length = 150 Score = 34.2 bits (77), Expect = 0.044, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 33/88 (37%), Gaps = 9/88 (10%) Query: 76 EFIAAVNLIMQEKMEQKL---KWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 EF+ +E + +KL K + +D + G ID L M + G E Sbjct: 32 EFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKL----GVPKTHLE 87 Query: 133 EFINLVFHKIDINNDGELTLEEFINGMA 160 + + ++ ++ +F+N M Sbjct: 88 --MKKMISEVTGGVSDTISYRDFVNMML 113 Score = 27.3 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 21/55 (38%) Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 FD N +G +D + + + K ++K + +I + ++M Sbjct: 58 EFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMM 112 Score = 26.5 bits (57), Expect = 8.4, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 111 NELLDMFMAVQALNGQQTLSPEEFI--NLVFHKIDINNDGELTLEEFINGMAK 161 E+ F+ Q + ++ L PE+ + + D+NN+GE+ L M K Sbjct: 27 AEINREFLCDQKYSDEENL-PEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEK 78 >2EC6-B nrPDB Length = 133 Score = 33.8 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 17/145 (11%), Positives = 49/145 (33%), Gaps = 14/145 (9%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLE 76 QE + T + + G +++ K G + + G ++F Sbjct: 2 QEMKEAF-TMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAML-----KEAPGPLNFTM 55 Query: 77 FIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI 135 F++ + + E+ ++ F ++D D ++ + D+ + + + Sbjct: 56 FLSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMR----- 110 Query: 136 NLVFHKIDINNDGELTLEEFINGMA 160 + F + + G+ F+ + Sbjct: 111 -MTFKEAPVEG-GKFDYVRFVAMIK 133 >2Y5I-A nrPDB Length = 99 Score = 33.8 bits (76), Expect = 0.054, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%), Gaps = 1/50 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 + K EL ++ A P + + + +D N D E+ EF+ Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDP-MLVEKIMNDLDSNKDNEVDFNEFV 76 Score = 29.6 bits (65), Expect = 0.99, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query: 35 QTLHEFKTLLGL----QGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLI 84 + E K LL ++QK ++++ N D+NKD VDF EF+ V + Sbjct: 29 LSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAAL 82 >1DJX-A nrPDB Length = 624 Score = 33.5 bits (75), Expect = 0.070, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 28/88 (31%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADG 104 G QK I D NKD ++F E + + + + + F+ D Sbjct: 1 GSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQ 60 Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPE 132 S++ E+ + + E Sbjct: 61 TDSLEDEEIETFYKMLTQRAEIDRAFEE 88 Score = 32.3 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 21/58 (36%), Gaps = 5/58 (8%) Query: 126 QQTLSPEEFINLVFHKIDINNDGELTLEEFING-----MAKDQDLLEIVYKSFDFSNV 178 Q + +I+ K D N D ++ +E + + D +++ D S Sbjct: 4 DQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQT 61 >1B7T-Y nrPDB Length = 156 Score = 33.1 bits (74), Expect = 0.082, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 24/52 (46%) Query: 79 AAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 + V + +K Q++K F + D D +G + K ++ + + + L+ Sbjct: 6 SGVLTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELT 57 Score = 31.9 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 17/159 (10%), Positives = 52/159 (32%), Gaps = 15/159 (9%) Query: 5 KSIAGDQKAVPTQETHVWYRTF--MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 K+ +G +P ++ F + G + + K + G + + Sbjct: 3 KAASGVLTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-- 60 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQ 121 G ++F F++ + + E+ ++ F ++D ++ + D+ + Sbjct: 61 ---KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMG 117 Query: 122 ALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 + + + F + + G+ +F + Sbjct: 118 DNFNKDEMR------MTFKEAPVEG-GKFDYVKFTAMIK 149 >1C07-A nrPDB Length = 95 Score = 33.1 bits (74), Expect = 0.10, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 27/64 (42%), Gaps = 8/64 (12%) Query: 92 KLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 K F D D +G + E+ ++F +T P + ++ D + G+L+ Sbjct: 11 KYDEIFLKTDKDMDGFVSGLEVREIF--------LKTGLPSTLLAHIWSLCDTKDCGKLS 62 Query: 152 LEEF 155 ++F Sbjct: 63 KDQF 66 >2MHH-A nrPDB Length = 96 Score = 33.1 bits (74), Expect = 0.10, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 55 KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL 114 I + D N D +DF E+ + + + ++ F YD DG+ +D E + Sbjct: 18 ADIQEALAHADANADQHLDFDEWRQEL--KCRGHADADIEAVFAKYDVDGDRVLDAEEQM 75 Query: 115 DMFMAVQALNGQ 126 M ++ Sbjct: 76 KMAHDLEGQKSD 87 >2AUC-A nrPDB Length = 126 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 9/61 (14%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 + +LE++ + ++L F +D + +G + KN++ ++ +Q + Sbjct: 47 YEQYLEYLTM--CVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEAN 104 Query: 131 P 131 Sbjct: 105 D 105 >6DU8-A nrPDB Length = 805 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 72 VDFLEFIAAVNLIMQEKME-QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 + F +F + + + E +L F +D DGN +D+ E M ++ Sbjct: 616 IQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTE 675 Query: 131 PEEF 134 E+ Sbjct: 676 IEKL 679 Score = 31.9 bits (71), Expect = 0.21, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 21/58 (36%), Gaps = 5/58 (8%) Query: 35 QTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQK 92 +F L G + + + FD + + +D E M++ +E++ Sbjct: 616 IQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKE-----QEKMRQDLEEE 668 >1WY9-A nrPDB Length = 147 Score = 32.7 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 39/100 (39%), Gaps = 12/100 (12%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKL----YDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 +F+ E + KL FK+ +D +GNG ID L M + G Sbjct: 29 KQFLDDPKYSNDEDLPSKL-EAFKVKYMEFDLNGNGDIDIMSLKRMLEKL----GVPKTH 83 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMA-KDQDLLEIV 169 E + + ++ ++ + +F+ M K +L ++ Sbjct: 84 LE--LKRLIREVSSGSEETFSYSDFLRMMLGKRSAILRMI 121 Score = 29.6 bits (65), Expect = 0.93, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 28/71 (39%) Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 FD N +G +D + + + K +LK + + + ++ L M + ++ Sbjct: 56 EFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFLRMMLGKRS 115 Query: 123 LNGQQTLSPEE 133 + L EE Sbjct: 116 AILRMILMYEE 126 >5HLO-A nrPDB Length = 94 Score = 32.7 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 24/62 (38%), Gaps = 3/62 (4%) Query: 37 LHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAA---VNLIMQEKMEQKL 93 + K LL + K D + D N DG V+F EF+ + + +K ++ Sbjct: 32 RDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEES 91 Query: 94 KW 95 Sbjct: 92 HK 93 Score = 30.8 bits (68), Expect = 0.41, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 24/52 (46%), Gaps = 5/52 (9%) Query: 110 KNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAK 161 +++L + ++ ++ F ++DIN DG + +EF+ + K Sbjct: 32 RDDLKKLLET-----ECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIK 78 >1DFK-Y nrPDB Length = 139 Score = 32.3 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 22/46 (47%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLS 130 + +K Q++K F + D D +G + K ++ + + + L+ Sbjct: 1 LPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELT 46 Score = 30.8 bits (68), Expect = 0.41, Method: Composition-based stats. Identities = 15/147 (10%), Positives = 47/147 (31%), Gaps = 14/147 (9%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 QE + ++ G + + K + G + + G ++F Sbjct: 5 QIQEMKEAFSMIDVDRD-GFVSKEDIKAISEQLGRAPDDKELTAML-----KEAPGPLNF 58 Query: 75 LEFIAAVNLIMQEK-MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 F++ + + E+ ++ F ++D ++ + D+ + + + Sbjct: 59 TMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKDEMR--- 115 Query: 134 FINLVFHKIDINNDGELTLEEFINGMA 160 + F + + G+ +F + Sbjct: 116 ---MTFKEAPVEG-GKFDYVKFTAMIK 138 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDK 110 QK + + + ++ D ++DGFV + A + + +++L K + G ++ Sbjct: 3 QKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLK----EAPGPLNF 58 Query: 111 NELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE 153 L +F + EE I F D +L +E Sbjct: 59 TMFLSIFS-----DKLSGTDSEETIRNAFAMFDEQETKKLNIE 96 >1FI6-A nrPDB Length = 92 Score = 32.3 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 25/61 (40%), Gaps = 8/61 (13%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 FK D NG I + + F + + ++ ++ D + DG LTL+EF Sbjct: 15 FKTIQPDLNGFIPGSAAKEFFTKSKLPILE--------LSHIWELSDFDKDGALTLDEFC 66 Query: 157 N 157 Sbjct: 67 A 67 Score = 27.3 bits (59), Expect = 5.1, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 18/34 (52%) Query: 56 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKM 89 + ++ D +KDG + EF AA +L++ K Sbjct: 44 ELSHIWELSDFDKDGALTLDEFCAAFHLVVARKN 77 Score = 26.9 bits (58), Expect = 6.3, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 32/82 (39%), Gaps = 9/82 (10%) Query: 61 YNTFDTNKDGFV---DFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMF 117 + T + +GF+ EF + + + L ++L D D +G++ +E F Sbjct: 15 FKTIQPDLNGFIPGSAAKEFFT----KSKLPILE-LSHIWELSDFDKDGALTLDEFCAAF 69 Query: 118 MAVQALNGQQTLSPEEFINLVF 139 V A L PE+ + Sbjct: 70 HLVVARKNGYDL-PEKLPESLM 90 >4HRG-A nrPDB Length = 115 Score = 31.5 bits (70), Expect = 0.25, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 + + + F + D G + K +L + + + ++ + +D DG++ Sbjct: 11 ETMMFTFHKFAGDK-GYLTKEDLRVLME-KEFPGFLENQKDPLAVDKIMKDLDQCRDGKV 68 Query: 151 TLEEF 155 + F Sbjct: 69 GFQSF 73 >3V4P-A nrPDB Length = 597 Score = 31.5 bits (70), Expect = 0.26, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 43/106 (40%), Gaps = 16/106 (15%) Query: 46 LQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGN 105 L G ++ A + + + N D + DGF D + + E L+ +Y+ + Sbjct: 325 LVGSDKYAARFGESIVNLGDIDNDGFED---------VAIGAPQEDDLQGAIYIYNGRAD 375 Query: 106 GSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 G I ++ L ++LS F + +ID +N+G + Sbjct: 376 G-IS----STFSQRIEGLQISKSLSM--FGQSISGQIDADNNGYVD 414 >4GFT-A nrPDB Length = 69 Score = 31.5 bits (70), Expect = 0.26, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 28/73 (38%), Gaps = 8/73 (10%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 144 + ++L F +D + G + K+++ ++ L+ +E I+ + Sbjct: 1 GDKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTW-----GDALTDQEAIDALNAFSSE 55 Query: 145 NNDGELTLEEFIN 157 +N + + F Sbjct: 56 DN---IDYKLFCE 65 >1NUB-A nrPDB Length = 229 Score = 31.5 bits (70), Expect = 0.27, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 24/64 (37%), Gaps = 9/64 (14%) Query: 93 LKWYFKLYDADG-NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + W F D +G + EL + + + T F D++ND + Sbjct: 157 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTT--------RFFETCDLDNDKYIA 208 Query: 152 LEEF 155 L+E+ Sbjct: 209 LDEW 212 >5X2E-A nrPDB Length = 80 Score = 31.5 bits (70), Expect = 0.27, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 19/62 (30%), Gaps = 8/62 (12%) Query: 96 YFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 F D DG I EL + + D +N G +TLE F Sbjct: 6 IFVSIDKDGTNVISYPELEQYVA--------ENNLDPSMVEKWKQLFDPDNTGSITLETF 57 Query: 156 IN 157 + Sbjct: 58 CS 59 Score = 29.6 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 60 VYNTFDTNKDGFVDFLEFIAAVNL-IMQEKMEQKLKWYFKLYDADGNGSIDKN 111 ++ + D + + + E V + M +K K +L+D D GSI Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSMVEKWK---QLFDPDNTGSITLE 55 >4FTG-A nrPDB Length = 96 Score = 31.2 bits (69), Expect = 0.33, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 + + + F + D G + K +L + + + ++ + +D DG++ Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLRVLME-KEFPGFLENQKDPLAVDKIMKDLDQCRDGKV 66 Query: 151 TLEEF 155 + F Sbjct: 67 GFQSF 71 >2JQ6-A nrPDB Length = 139 Score = 31.2 bits (69), Expect = 0.35, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 19/51 (37%), Gaps = 8/51 (15%) Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 NG I + ++ P + ++ D++ DG L EEF Sbjct: 64 NGKITGANAKKEMV--------KSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >2KFH-A nrPDB Length = 105 Score = 31.2 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 19/51 (37%), Gaps = 8/51 (15%) Query: 105 NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 NG I + ++ P + ++ D++ DG L EEF Sbjct: 30 NGKITGANAKKEMV--------KSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 Score = 27.3 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 5/88 (5%) Query: 4 GKSIAGDQKAVPTQETHVWYRTFMMEYP-SGLQTLHEFKTLLGLQGLNQKANKHIDQVYN 62 G + D + V ++ + F P +G T K + L N + +++ Sbjct: 1 GPLGSDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKL---PNTVLGKIWK 57 Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKME 90 D +KDG +D EF A N +++ K+E Sbjct: 58 LADVDKDGLLDDEEF-ALANHLIKVKLE 84 >6QAA-A nrPDB Length = 557 Score = 31.2 bits (69), Expect = 0.38, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 24/67 (35%), Gaps = 1/67 (1%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQGLNQKA-NKHIDQVYNTFDTNKDGFVDFLEFIAAVNL 83 F+ + P L L +FK L G+N+ + F + + + EF + + Sbjct: 325 DFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKI 384 Query: 84 IMQEKME 90 E Sbjct: 385 FFPGVSE 391 >5LXV-B nrPDB Length = 88 Score = 31.2 bits (69), Expect = 0.38, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 5/49 (10%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNEL 113 D + DG VD + I + E+ F+ D + +G ID ++L Sbjct: 27 DLDGDGEVDVFDLILMRKAVENGDTER-----FEAADLNCDGVIDSDDL 70 Score = 28.8 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 17/67 (25%) Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLE------E 154 D DG+G +D +L+ M AV+ + ++ F D+N DG + + E Sbjct: 27 DLDGDGEVDVFDLILMRKAVENGDTER-----------FEAADLNCDGVIDSDDLTYHSE 75 Query: 155 FINGMAK 161 +++G+ K Sbjct: 76 YLHGIRK 82 >6EMI-A nrPDB Length = 532 Score = 30.8 bits (68), Expect = 0.43, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 1/61 (1%) Query: 25 TFMMEYPSGLQTLHEFKTLLGLQGLNQKA-NKHIDQVYNTFDTNKDGFVDFLEFIAAVNL 83 F+ + P L L +FK L G+N+ + F + D + EF + + Sbjct: 300 DFLTDMPDTLLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNDSIITRKEFQEGLKV 359 Query: 84 I 84 Sbjct: 360 F 360 >1SNL-A nrPDB Length = 103 Score = 30.8 bits (68), Expect = 0.48, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 30/77 (38%), Gaps = 10/77 (12%) Query: 97 FKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI----------NLVFHKIDINN 146 F L+D + +G +D+ EL +F ++ V +D N Sbjct: 26 FILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQ 85 Query: 147 DGELTLEEFINGMAKDQ 163 D +TLEEF+ + + Sbjct: 86 DRLVTLEEFLASTQRKE 102 >2M7L-A nrPDB Length = 144 Score = 30.8 bits (68), Expect = 0.49, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 46/111 (41%), Gaps = 4/111 (3%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 Q+ K F +D + +G +DK E ++ ++ T + + +++ + +G + Sbjct: 12 QEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNNVTKGENG-V 70 Query: 151 TLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKA 201 + + ++ M + D + + + I GK ETD K+ A Sbjct: 71 SFDNYVQYMKEKNDENPSPEQ---LNEIFSTIAAGKDSITETDMQKAGMSA 118 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 23/46 (50%) Query: 45 GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 G+ + + Q ++ FD N DG +D LEF + ++ + ++ Sbjct: 2 SSSGVTAEQMQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDID 47 >5FOJ-B nrPDB Length = 504 Score = 30.4 bits (67), Expect = 0.53, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 4/39 (10%) Query: 150 LTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQP 188 + EF D++ +EI + FDF++ + G+ P Sbjct: 351 VDFSEF----TLDKEEIEIGSRFFDFTSNTCRVSMGENP 385 >2QPT-A nrPDB Length = 550 Score = 30.0 bits (66), Expect = 0.73, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 128 TLSPEEFINLVFHKIDINNDGELTLEEF 155 T P + ++ D++ DG L EEF Sbjct: 486 TKLPNSVLGRIWKLSDVDRDGMLDDEEF 513 >2JMM-A nrPDB Length = 156 Score = 30.0 bits (66), Expect = 0.82, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%), Gaps = 2/34 (5%) Query: 101 DADGNGSIDKNE--LLDMFMAVQALNGQQTLSPE 132 D DGNG I E + +F ++ ++PE Sbjct: 90 DKDGNGYISAAEASVSPVFAGGVEYVIRRRITPE 123 >5MV8-A nrPDB Length = 527 Score = 30.0 bits (66), Expect = 0.82, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 55/178 (30%), Gaps = 23/178 (12%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +E W + + TL + LN K D N D + + Sbjct: 273 SLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGK---------DVNADTILHY 323 Query: 75 -LEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELL---DMFMAVQALNGQQTLS 130 E + + E + +Y A N D+++L + + N + +S Sbjct: 324 HQELPKYLRGFHKCSREDAIHLAGLIYKAQFNN--DRSQLASVPKILRELVPENLTRLMS 381 Query: 131 PEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQP 188 EE+ + D + D + EE L+ + + F + + +P Sbjct: 382 SEEWKKSILLAYDKHKDKTV--EE------AKVAFLKWICRWPTFGSAFFEVKQTSEP 431 >3POK-A nrPDB Length = 167 Score = 29.6 bits (65), Expect = 0.86, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 39/96 (40%), Gaps = 15/96 (15%) Query: 51 QKANKHIDQVYNTFDTNKDGFVDFLEF-----IAAVNLIMQEKMEQKLKWYFKLYDADG- 104 ++ N ++ V DTN DG+++ E + +V+ K + + ++ F + + Sbjct: 64 KEKNLYLSCVLGYIDTNNDGWIEGDELYPTLQLESVDPKNYPKKKMEKRFVFNKIEINNK 123 Query: 105 ---------NGSIDKNELLDMFMAVQALNGQQTLSP 131 N I ++ +M + + G Q ++ Sbjct: 124 LEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITD 159 >5MVF-A nrPDB Length = 523 Score = 29.6 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 29/83 (34%), Gaps = 16/83 (19%) Query: 73 DFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPE 132 D E++ A + + +L + NG I A + + + P Sbjct: 420 DEEEWVVA----KDKPVYDELFYTLSPI----NGKISG------VNAKKEMVTSKL--PN 463 Query: 133 EFINLVFHKIDINNDGELTLEEF 155 + ++ D + DG L EEF Sbjct: 464 SVLGKIWKLADCDCDGMLDEEEF 486 >3QR0-A nrPDB Length = 816 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 29/71 (40%), Gaps = 9/71 (12%) Query: 135 INLVFHKIDINNDGELT---LEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDME 191 I +F ++ N G +T +F+N M + L + ++ + + C D E Sbjct: 231 IEGIFKELSKNK-GNITTVMFRDFLNDMQRHPSLHKTLFPLYTDAQ-----CEALINDYE 284 Query: 192 TDSSKSPDKAG 202 + +K K G Sbjct: 285 SAVNKKGKKKG 295 >1SRA-A nrPDB Length = 151 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 24/64 (37%), Gaps = 9/64 (14%) Query: 93 LKWYFKLYDADG-NGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELT 151 + W F D +G + EL + + + T F D++ND + Sbjct: 79 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTT--------RFFETCDLDNDKYIA 130 Query: 152 LEEF 155 L+E+ Sbjct: 131 LDEW 134 >5KU1-A nrPDB Length = 424 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 85 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKI-D 143 M+ + L FK+ D D +G+++ EL + F + + E+ N+V I D Sbjct: 5 MKPACIKALTRIFKISDQDNDGTLNDAEL-NFFQRICFNTPLAPQALEDVKNVVRKHISD 63 Query: 144 INNDGELTLEEFI 156 D LTL+ F+ Sbjct: 64 GVADSGLTLKGFL 76 >2KAY-A nrPDB Length = 92 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 1/74 (1%) Query: 12 KAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGL-QGLNQKANKHIDQVYNTFDTNKDG 70 + T +++ E + E K L+ L + ID + + D N D Sbjct: 6 EKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQ 65 Query: 71 FVDFLEFIAAVNLI 84 +DF E+ + ++ Sbjct: 66 EIDFKEYSVFLTML 79 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 23/49 (46%), Gaps = 4/49 (8%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 ++ + EL ++ L + E I+ + +D N+D E+ +E+ Sbjct: 28 TLSRKELKELIKKELCLGEMK----ESSIDDLMKSLDKNSDQEIDFKEY 72 >2Y3N-B nrPDB Length = 71 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 25/54 (46%), Gaps = 9/54 (16%) Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 154 D +G+G I+ +++ + + G ++ K D+NNDG + ++ Sbjct: 8 DLNGDGVINMADVMILAQSFGKAIGNPGVN---------EKADLNNDGVINSDD 52 >1XX7-A nrPDB Length = 184 Score = 29.2 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 33/87 (37%), Gaps = 2/87 (2%) Query: 11 QKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDG 70 QK + +E + P + E+ L L+G K +D + ++ G Sbjct: 90 QKYLNKEEAEA--KALKDVLPEYTELFEEYSKALTLEGQLVKIADKLDMIIQAYEYELSG 147 Query: 71 FVDFLEFIAAVNLIMQEKMEQKLKWYF 97 + EF A+ + + ++ + L+ Sbjct: 148 AKNLSEFWNALEDLEKLEISRYLREII 174 >5NRM-B nrPDB Length = 66 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 20/58 (34%), Gaps = 6/58 (10%) Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFING 158 D DGNGSI+ + M + + D+N D + + +F Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDD------IKAGDLNGDKSININDFAIM 55 Score = 27.7 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 29/62 (46%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 D + +G ++ ++F N ++ + + K D +G+ SI+ N+ M M + + Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSININDFAIMRMYLLGMI 63 Query: 125 GQ 126 + Sbjct: 64 TK 65 >4PCW-A nrPDB Length = 94 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 17/47 (36%) Query: 44 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 N +D + D + + +DF EF+ V + Q E Sbjct: 43 FRQILKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFKLAQAYYE 89 Score = 27.3 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 5/29 (17%), Positives = 17/29 (58%) Query: 133 EFINLVFHKIDINNDGELTLEEFINGMAK 161 + +++ +DI+++ ++ EF+ + K Sbjct: 54 DMVDVFMDHLDIDHNKKIDFTEFLLMVFK 82 >4C0K-A nrPDB Length = 423 Score = 29.2 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFM 118 +Q L F+ YD DG+G++ E +F Sbjct: 132 QQFLIAVFERYDRDGDGALSPEEHKMLFS 160 >4YBH-B nrPDB Length = 92 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 ++ K EL ++ +Q + + I + +D N D E+ +E++ Sbjct: 30 TLSKKELKEL---IQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYV 76 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 34 LQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 + E K L+ + + I ++ D NKD V+F E++ + + E Sbjct: 30 TLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNE 88 >5VP3-A nrPDB Length = 206 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 21/48 (43%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF 134 KM ++L F +D D +G + +E++ ++ L E+ Sbjct: 30 PKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKM 77 >5LPU-C nrPDB Length = 104 Score = 28.8 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 ++K+EL ++ + + + E + +D N D E+ +E+ Sbjct: 31 KLNKSELKELLTR-ELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYC 79 Score = 26.9 bits (58), Expect = 6.1, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 30/83 (36%), Gaps = 4/83 (4%) Query: 4 GKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLN----QKANKHIDQ 59 G +A + +++ E E K LL + + + + Sbjct: 1 GSHMACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQK 60 Query: 60 VYNTFDTNKDGFVDFLEFIAAVN 82 + + D+N+D VDF E+ ++ Sbjct: 61 LMSNLDSNRDNEVDFQEYCVFLS 83 >3NSO-A nrPDB Length = 101 Score = 28.8 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 37 LHEFKTLLGLQGLNQKANKHID----QVYNTFDTNKDGFVDFLEFIAAVN 82 E K LL + + + + + DTNKD VDF+E++ ++ Sbjct: 31 QAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLA 80 >1IQ3-A nrPDB Length = 110 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 25/64 (39%), Gaps = 5/64 (7%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQKAN-KHIDQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 + PS + ++ K + + ++ D + DG + EF AA +LI+ Sbjct: 31 LQPDPSSFIS----GSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIV 86 Query: 86 QEKM 89 K Sbjct: 87 ARKN 90 Score = 27.7 bits (60), Expect = 3.9, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 8/72 (11%) Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 E+ + F+ D + I + + F + PE ++ ++ D + Sbjct: 17 TEEQREYYVNQFRSLQPDPSSFISGSVAKNFFT------KSKLSIPE--LSYIWELSDAD 68 Query: 146 NDGELTLEEFIN 157 DG LTL EF Sbjct: 69 CDGALTLPEFCA 80 >6R5K-D nrPDB Length = 581 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 50/148 (33%), Gaps = 22/148 (14%) Query: 15 PTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 74 +ET Y ++ + T +F+ L G A+ D + Sbjct: 214 QLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEK-------DADGK----- 261 Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI-------DKNELLDMFMAVQALNGQQ 127 + + EK E +K L D++ NG KNE + + + Sbjct: 262 ---LKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLE 318 Query: 128 TLSPEEFINLVFHKIDINNDGELTLEEF 155 ++ + +NL +D + D E EEF Sbjct: 319 KMAKYQGVNLFVKNLDDSVDDEKLEEEF 346 >3QR1-A nrPDB Length = 813 Score = 28.5 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 20/42 (47%), Gaps = 4/42 (9%) Query: 135 INLVFHKIDINNDGELT---LEEFINGMAKDQDLLEIVYKSF 173 I +F ++ N G +T +F+N M + L + ++ + Sbjct: 231 IEGIFKELSQNK-GNITTVMFRDFLNDMQRHPSLHKTLFPLY 271 >5LJ6-A nrPDB Length = 664 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 32/91 (35%), Gaps = 9/91 (9%) Query: 18 ETHVWYRTF--------MMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKD 69 E R F +++ S +F ++G G + +I +T T Sbjct: 25 EIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTA-TGGS 83 Query: 70 GFVDFLEFIAAVNLIMQEKMEQKLKWYFKLY 100 +D E I N + + QK + F+ Y Sbjct: 84 SKIDGKETIELTNDQLSDLRSQKFGFIFQRY 114 >4DUQ-A nrPDB Length = 98 Score = 28.1 bits (61), Expect = 2.6, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155 + K E+ ++ + + EE + + +D N+D ++ +E+ Sbjct: 29 KLSKGEMKELLHKELPSFVGEKV-DEEGLKKLMGSLDENSDQQVDFQEY 76 >4CFQ-A nrPDB Length = 91 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 21/50 (42%), Gaps = 1/50 (2%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 ++K+EL ++ + + E + +D N D E+ +E+ Sbjct: 31 KLNKSELKELLTRELPSFLGKR-TDEAAFQKLMSNLDSNRDNEVDFQEYC 79 Score = 26.9 bits (58), Expect = 6.8, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 30/83 (36%), Gaps = 4/83 (4%) Query: 4 GKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLN----QKANKHIDQ 59 G +A + +++ E E K LL + + + + Sbjct: 1 GSHMASPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQK 60 Query: 60 VYNTFDTNKDGFVDFLEFIAAVN 82 + + D+N+D VDF E+ ++ Sbjct: 61 LMSNLDSNRDNEVDFQEYCVFLS 83 >4V6W-Az nrPDB Length = 844 Score = 28.1 bits (61), Expect = 2.8, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 27/75 (36%), Gaps = 8/75 (10%) Query: 75 LEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEF 134 F A Q++ E K F +Y D + +F A+ ++ + E Sbjct: 253 ENFFNAKTKKWQKQKEADNKRSFCMYILDP--------IYKVFDAIMNYKKEEIGTLLEK 304 Query: 135 INLVFHKIDINNDGE 149 I + D + DG+ Sbjct: 305 IGVTLKHEDKDKDGK 319 >4MN0-A nrPDB Length = 208 Score = 27.7 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 23/52 (44%) Query: 87 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLV 138 KM +L F +D D +G ++ +E+L ++ L E+ + V Sbjct: 32 PKMLSRLYKRFDTFDLDSDGKMEMDEVLYWPDRMRQLVNATDEQVEKMRDAV 83 >2KLD-A nrPDB Length = 123 Score = 27.7 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 G ++F E + + + +++ F YD DG+ + ++E M ++ Sbjct: 59 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDL 116 Query: 128 TLS 130 L Sbjct: 117 DLD 119 >5NRK-B nrPDB Length = 68 Score = 27.7 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 20/58 (34%), Gaps = 6/58 (10%) Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFING 158 D DGNGSI+ N+ M + + D+N D + +F Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDD------IKAGDLNGDKSINSLDFAIM 55 Score = 27.3 bits (59), Expect = 5.4, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 27/62 (43%) Query: 65 DTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALN 124 D + +G ++ +F N ++ + + K D +G+ SI+ + M M + + Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSINSLDFAIMRMYLLGMI 63 Query: 125 GQ 126 + Sbjct: 64 TK 65 >1QJT-A nrPDB Length = 99 Score = 27.7 bits (60), Expect = 3.7, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 13/25 (52%) Query: 131 PEEFINLVFHKIDINNDGELTLEEF 155 P+ + ++ D + G L+ +EF Sbjct: 43 PDLILGKIWDLADTDGKGVLSKQEF 67 >3TO3-A nrPDB Length = 619 Score = 27.7 bits (60), Expect = 4.3, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 149 ELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPD 189 + L++F G+ + L+ + K DF+ + + NGK D Sbjct: 454 RIALKDFHEGLEFYRPFLKEMNKCPDFTKMHKTYANGKMND 494 >5CUU-A nrPDB Length = 414 Score = 27.3 bits (59), Expect = 4.3, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 44/130 (33%), Gaps = 18/130 (13%) Query: 27 MMEYPSGLQTLHEFKTLLGLQGLNQKANKHI-DQVYNTFDTNKDGFVDFLEFIAAVNLIM 85 M E S T L N K + FD G EF ++ Sbjct: 23 MAEVASLHVANSYIGTGLDTSLENVKPLPEACKRNVTEFDLVAYGK---DEFTLSME--- 76 Query: 86 QEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDIN 145 ++ + F +D G +++ ++ M + + E+ + + +I+ Sbjct: 77 ----KRVMARMFSAFDVTQLGYLEERKIEHMCKYLGRVMN------EDDVKQMKSEINA- 125 Query: 146 NDGELTLEEF 155 DG +T E+F Sbjct: 126 IDGHITFEKF 135 >2FNA-A nrPDB Length = 357 Score = 27.3 bits (59), Expect = 4.9, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 23/68 (33%), Gaps = 6/68 (8%) Query: 13 AVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFV 72 + E + Y +E P F T+ ++A + + + + D + Sbjct: 174 IMSGSEMGLLYDYLRVEDPESPLFGRAFSTVELKPFSREEAIEFLRRGFQEAD------I 227 Query: 73 DFLEFIAA 80 DF ++ Sbjct: 228 DFKDYEVV 235 >2JTT-A nrPDB Length = 90 Score = 27.3 bits (59), Expect = 5.0, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 23 YRTFMMEYPSGLQTLHEFKTLLGLQGLNQK--ANKHIDQVYNTFDTNKDGFVDFLEFIAA 80 ++ E + E K L+ + + I ++ + D NKD V+F E+I Sbjct: 17 HKYSGKEGDKHTLSKKELKELIQKELTIGSKLQDAEIVKLMDDLDRNKDQEVNFQEYITF 76 Query: 81 VNLIMQEKME 90 + + E Sbjct: 77 LGALAMIYNE 86 Score = 27.3 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 107 SIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFI 156 ++ K EL ++ + L L E + + +D N D E+ +E+I Sbjct: 28 TLSKKELKELIQ--KELTIGSKLQDAEIV-KLMDDLDRNKDQEVNFQEYI 74 >1E6V-C nrPDB Length = 258 Score = 27.3 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 17/44 (38%) Query: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEE 133 E LK +Y DG + ELL + + L PEE Sbjct: 211 EDDLKERTTIYRIDGTPYREDEELLQVVQRIHELRTLAGYRPEE 254 >2G2B-A nrPDB Length = 150 Score = 26.9 bits (58), Expect = 5.6, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 32/80 (40%), Gaps = 7/80 (8%) Query: 91 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 150 + K + +D +GNG ID L M + G E + + ++ + Sbjct: 51 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKL----GVPKTHLE--LKKLIGEVSSGSGETF 104 Query: 151 TLEEFINGMA-KDQDLLEIV 169 + +F+ M K +L+++ Sbjct: 105 SYPDFLRMMLGKRSAILKMI 124 Score = 26.5 bits (57), Expect = 7.8, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 26/71 (36%) Query: 63 TFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQA 122 FD N +G +D + + + K +LK + + + L M + ++ Sbjct: 59 EFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRS 118 Query: 123 LNGQQTLSPEE 133 + L EE Sbjct: 119 AILKMILMYEE 129 >5CUY-A nrPDB Length = 414 Score = 26.9 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 9/72 (12%), Positives = 25/72 (34%), Gaps = 7/72 (9%) Query: 84 IMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKID 143 Q +++ + F +D G + +++ ++ + + + Sbjct: 72 FTQPMIKKIMSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINAI---- 127 Query: 144 INNDGELTLEEF 155 DG +T E+F Sbjct: 128 ---DGHVTFEKF 136 >2DTU-A nrPDB Length = 896 Score = 26.9 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 37/124 (29%), Gaps = 3/124 (2%) Query: 17 QETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQV-YNTFDTNKDGFVDFL 75 ++ W + M + + +FK N + ++ FD F Sbjct: 66 RDASQWIKR-MEDIGLEALGMDDFKLAYLSDTYNYEIKYDHTKIRVANFDIEVTSPDGFP 124 Query: 76 EFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFI 135 E A + I + F ++D + + E A G + P E I Sbjct: 125 EPSQAKHPIDAITHYDSIDDRFYVFDLLNSPYGNVEEWSIEIAAKLQEQGGDEV-PSEII 183 Query: 136 NLVF 139 + + Sbjct: 184 DKII 187 >2KQ6-A nrPDB Length = 78 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 68 KDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQ 127 G ++F E + + + +++ F YD DG+ + ++E M ++ Sbjct: 13 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDL 70 Query: 128 TLS 130 L Sbjct: 71 DLD 73 >2QXL-A nrPDB Length = 658 Score = 26.5 bits (57), Expect = 8.5, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 25/73 (34%), Gaps = 8/73 (10%) Query: 101 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMA 160 D D + + + EL ++ + + L ++D E I G Sbjct: 293 DVDVSSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVD--------FVEIIGGTT 344 Query: 161 KDQDLLEIVYKSF 173 + L + + ++F Sbjct: 345 RIPTLKQSISEAF 357 >2CXJ-A nrPDB Length = 98 Score = 26.5 bits (57), Expect = 9.0, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 32 SGLQTLHEFKTLLGLQGLNQ-KANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME 90 G ++EFK L Q + K +D+ T D N+D + F E+ + + +E + Sbjct: 30 KGSLNINEFKELATQQLPHLLKDVGSLDEKMKTLDVNQDSELRFSEYWRLIGELAKEVRK 89 Query: 91 QK 92 +K Sbjct: 90 EK 91 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.137 0.367 Lambda K H 0.267 0.0420 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,432,520 Number of Sequences: 36641 Number of extensions: 336953 Number of successful extensions: 4069 Number of sequences better than 10.0: 357 Number of HSP's better than 10.0 without gapping: 469 Number of HSP's successfully gapped in prelim test: 104 Number of HSP's that attempted gapping in prelim test: 1371 Number of HSP's gapped (non-prelim): 1469 length of query: 209 length of database: 10,336,785 effective HSP length: 93 effective length of query: 116 effective length of database: 6,929,172 effective search space: 803783952 effective search space used: 803783952 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.5 bits)