BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O95154 (331 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2CLP-A nrPDB 677 0.0 2BP1-A nrPDB 573 e-164 1GVE-A nrPDB 558 e-159 2C91-A nrPDB 557 e-159 1PYF-A nrPDB 112 3e-25 1PZ1-A nrPDB 85 4e-17 3EB3-A nrPDB 85 5e-17 3N6Q-A nrPDB 84 1e-16 4MHB-A nrPDB 62 4e-10 1LQA-A nrPDB 60 1e-09 4JQA-A nrPDB 54 1e-07 4GIE-A nrPDB 53 2e-07 2FVL-A nrPDB 52 3e-07 3UP8-A nrPDB 50 1e-06 3WCZ-A nrPDB 49 2e-06 2BGQ-A nrPDB 49 3e-06 4F40-A nrPDB 47 2e-05 3KRB-A nrPDB 46 2e-05 1VBJ-A nrPDB 46 2e-05 1Q5M-A nrPDB 45 3e-05 5JM5-A nrPDB 45 5e-05 4HBK-A nrPDB 44 8e-05 2HE8-A nrPDB 44 8e-05 1OG6-A nrPDB 44 9e-05 3H7R-A nrPDB 44 1e-04 1QWK-A nrPDB 42 4e-04 3H7U-A nrPDB 42 5e-04 4R9O-A nrPDB 41 6e-04 3D3F-A nrPDB 40 0.001 4H8N-A nrPDB 38 0.005 5JH1-A nrPDB 38 0.007 1VP5-A nrPDB 37 0.008 1MZR-A nrPDB 37 0.010 1MDF-A nrPDB 37 0.010 4OTK-A nrPDB 37 0.011 5Z6T-A nrPDB 37 0.016 5UXF-A nrPDB 37 0.017 4GAC-A nrPDB 36 0.028 2ALR-A nrPDB 35 0.039 1WSA-A nrPDB 33 0.12 1HQT-A nrPDB 32 0.51 1AFS-A nrPDB 32 0.56 1A80-A nrPDB 30 1.0 1XQ8-A nrPDB 28 3.9 1ITU-A nrPDB 28 4.8 4AZW-A nrPDB 28 5.7 >2CLP-A nrPDB Length = 347 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/326 (99%), Positives = 324/326 (99%) Query: 6 SRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL 65 S ARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL Sbjct: 22 SMARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL 81 Query: 66 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL 125 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL Sbjct: 82 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL 141 Query: 126 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP 185 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP Sbjct: 142 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP 201 Query: 186 CLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGI 245 CLRHFGLRFYAFNPLAGGLLTGKYKYEDK+GKQPVGRFFGNTWAEMYRNRYWKEHHFEGI Sbjct: 202 CLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGI 261 Query: 246 ALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG 305 ALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG Sbjct: 262 ALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG 321 Query: 306 PLEPAVVDAFNQAWHLVTHECPNYFR 331 PLEPAVVDAFNQAWHLV HECPNYFR Sbjct: 322 PLEPAVVDAFNQAWHLVAHECPNYFR 347 >2BP1-A nrPDB Length = 360 Score = 573 bits (1476), Expect = e-164, Method: Compositional matrix adjust. Identities = 290/335 (86%), Positives = 306/335 (91%), Gaps = 5/335 (1%) Query: 2 SRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSET 56 +R L+ +RP A+VLG MEMGRRMDAP SAA RAFLERGHTE+DTAF+YS+GQSET Sbjct: 26 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 85 Query: 57 ILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD 116 ILGGLGL LGG DCRVKI TKA P G SLKPDS+R QLETSLKRLQCP+VDLFYLH PD Sbjct: 86 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 145 Query: 117 HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAIT 176 H TPVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMYNA T Sbjct: 146 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 205 Query: 177 RQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRY 236 RQVETELFPCLRHFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFGN+WAE YRNR+ Sbjct: 206 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRF 265 Query: 237 WKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLE 296 WKEHHFE IALVEKALQAAYGASAPS+TSA LRWMYHHSQLQGAHGDAVILGMSSLEQLE Sbjct: 266 WKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 325 Query: 297 QNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR 331 QNLAA EEGPLEPAVVDAFNQAWHLV HECPNYFR Sbjct: 326 QNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR 360 >1GVE-A nrPDB Length = 327 Score = 558 bits (1437), Expect = e-159, Method: Compositional matrix adjust. Identities = 264/327 (80%), Positives = 292/327 (89%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLR 64 +S+ARPATVLGAMEMGRRMD +S+A RAFL+RGHTEIDTAFVY+ GQSETILG LGL Sbjct: 1 MSQARPATVLGAMEMGRRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLG 60 Query: 65 LGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEET 124 LG S C+VKI TKA P+FG +LKP +RFQLETSLKRLQCPRVDLFYLH PDH TP+EET Sbjct: 61 LGRSGCKVKIATKAAPMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFPDHGTPIEET 120 Query: 125 LRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELF 184 L+ACHQLHQEGKFVELGLSNY +WEVAEICTLCK NGWI+PTVYQGMYNAITRQVETELF Sbjct: 121 LQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELF 180 Query: 185 PCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEG 244 PCLRHFGLRFYAFNPLAGGLLTG+YKY+DK+GK P RFFGN ++++Y +RYWKE HF G Sbjct: 181 PCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKEEHFNG 240 Query: 245 IALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEE 304 IALVEKAL+ YG +APSM SA +RWMYHHSQL+G GDAVILGMSSLEQLEQNLA EE Sbjct: 241 IALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNLALVEE 300 Query: 305 GPLEPAVVDAFNQAWHLVTHECPNYFR 331 GPLEPAVVDAF+QAW+LV HECPNYFR Sbjct: 301 GPLEPAVVDAFDQAWNLVAHECPNYFR 327 >2C91-A nrPDB Length = 338 Score = 557 bits (1435), Expect = e-159, Method: Compositional matrix adjust. Identities = 275/323 (85%), Positives = 289/323 (89%) Query: 9 RPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGS 68 RPATVLG MEMGRRMDA SAA RAFLERGH+E+DTAF+Y +GQSE ILGGLGL LG Sbjct: 16 RPATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSG 75 Query: 69 DCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRAC 128 DC VKI TKA P G SLKPDS+R QLETSLKRLQCPRVDLFYLH PDHSTPVEETL AC Sbjct: 76 DCTVKIATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAPDHSTPVEETLCAC 135 Query: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLR 188 HQLHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMYNA TRQVE EL PCLR Sbjct: 136 HQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLR 195 Query: 189 HFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALV 248 HFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFGN WAE YRNR+WKEHHFE IALV Sbjct: 196 HFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNNWAETYRNRFWKEHHFEAIALV 255 Query: 249 EKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLE 308 EKALQ YG +AP MTSA LRWMYHHSQLQG GDAVILGMSSLEQLEQNLAA EEGPLE Sbjct: 256 EKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLE 315 Query: 309 PAVVDAFNQAWHLVTHECPNYFR 331 PAVV+AF+QAW++V HECPNYFR Sbjct: 316 PAVVEAFDQAWNMVAHECPNYFR 338 >1PYF-A nrPDB Length = 312 Score = 112 bits (279), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 67/206 (32%), Positives = 104/206 (50%), Gaps = 17/206 (8%) Query: 11 ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70 +G + ++ T + R + G T +DTA++Y G+SE ++G + D Sbjct: 20 TNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREFNRED- 78 Query: 71 RVKIDTKAIP-------LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEE 123 V I TKA +F NS PD L+ ++ SLKRL +DLFY+H PD TP +E Sbjct: 79 -VVIATKAAHRKQGNDFVFDNS--PDFLKKSVDESLKRLNTDYIDLFYIHFPDEHTPKDE 135 Query: 124 TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETEL 183 + A +++ + GK +G+SN++ ++ E +N L V QG YN + R+ E Sbjct: 136 AVNALNEMKKAGKIRSIGVSNFSLEQLKE------ANKDGLVDVLQGEYNLLNREAEKTF 189 Query: 184 FPCLRHFGLRFYAFNPLAGGLLTGKY 209 FP + + F + PL GLL GKY Sbjct: 190 FPYTKEHNISFIPYFPLVSGLLAGKY 215 >1PZ1-A nrPDB Length = 333 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 66/208 (31%), Positives = 98/208 (47%), Gaps = 16/208 (7%) Query: 14 LGAMEMGRRM----DAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSD 69 LG +G M D TS RA L++G T IDTA Y GQSE I+G D Sbjct: 18 LGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGKAIKEYMKRD 77 Query: 70 -----CRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEET 124 + +D K LF ++ + + ++E SLKRLQ +DL+ +H PD P+EET Sbjct: 78 QVILATKTALDWKNNQLFRHANRARIVE-EVENSLKRLQTDYIDLYQVHWPDPLVPIEET 136 Query: 125 LRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELF 184 +L+ GK +G+SN++ ++ + L T+ Q YN R++E + Sbjct: 137 AEVMKELYDAGKIRAIGVSNFSIEQMDTFRAVAP-----LHTI-QPPYNLFEREMEESVL 190 Query: 185 PCLRHFGLRFYAFNPLAGGLLTGKYKYE 212 P + + + L GLLTGK E Sbjct: 191 PYAKDNKITTLLYGSLCRGLLTGKMTEE 218 >3EB3-A nrPDB Length = 327 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 80/297 (26%), Positives = 136/297 (45%), Gaps = 27/297 (9%) Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79 G+ D +T A+ + G DTA VY+ G++E +LG + + G + I TK Sbjct: 28 GQITDEMAEHLMTLAY-DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTK-- 84 Query: 80 PLFGNS-------LKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLH 132 +F L + L+ SL+RLQ VD+ + + PD +TP+EET+RA + Sbjct: 85 -IFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVI 143 Query: 133 QEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFG 191 +G + G S +++ E+ E ++ + I P Q Y+ R+ VE +L G Sbjct: 144 NQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIG 203 Query: 192 LRFYAFNPLAGGLLTGKYKYEDKNGKQPVGR--FFGNTWAEMYRNRYWKEHHFEGIALVE 249 + ++PLA G+++GKY +G P R G W +++ E A + Sbjct: 204 VGAMTWSPLACGIVSGKY----DSGIPPYSRASLKGYQW---LKDKILSEEGRRQQAKL- 255 Query: 250 KALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306 K LQA ++ + W + + +V+LG S+ EQL +N+ A + P Sbjct: 256 KELQAIAERLGCTLPQLAIAWCLRNEGV-----SSVLLGASNAEQLMENIGAIQVLP 307 >3N6Q-A nrPDB Length = 346 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/211 (31%), Positives = 101/211 (47%), Gaps = 20/211 (9%) Query: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEIC 154 L+ SLKR+ VD+FY H D +TP+EET A Q GK + +G+S+Y+ ++ Sbjct: 120 LDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMV 179 Query: 155 TLCKSNGWILP-TVYQGMYNAITRQVETE-LFPCLRHFGLRFYAFNPLAGGLLTGKYKYE 212 L + W +P ++Q YN + R V+ L L++ G+ AF PLA GLLTGKY Sbjct: 180 ELLRE--WKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKY--- 234 Query: 213 DKNGKQPVGRFF--GNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRW 270 NG R GN + E + + L+ + Q SM L W Sbjct: 235 -LNGIPQDSRMHREGNK-VRGLTPKMLTEANLNSLRLLNEMAQ----QRGQSMAQMALSW 288 Query: 271 MYHHSQLQGAHGDAVILGMSSLEQLEQNLAA 301 + ++ +V++G S EQLE+N+ A Sbjct: 289 LLKDDRVT-----SVLIGASRAEQLEENVQA 314 >4MHB-A nrPDB Length = 297 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 55/169 (32%), Positives = 82/169 (48%), Gaps = 16/169 (9%) Query: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGG-SDCRVKIDTKAIPLFGNSLKPDSLRFQ 94 +E G+ IDTA Y Q+ET +G L+L G + + I TK L+ + + Q Sbjct: 50 IETGYRLIDTAASY---QNETQVGN-ALKLSGIARDELFITTK---LWLQDTYYEGAKAQ 102 Query: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEIC 154 E SL RLQ VDL+ +H P V RA +LHQ GK +G+SN+ +A++ Sbjct: 103 FERSLNRLQLDYVDLYLIHQP--YGDVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLM 160 Query: 155 TLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGG 203 K I+P V Q N +Q+ P ++ G++ A+ P A G Sbjct: 161 AFNK----IIPAVNQIEVNPFNQQLHA--VPWMQSRGIQPEAWAPFAEG 203 >1LQA-A nrPDB Length = 346 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 61/240 (25%), Positives = 97/240 (40%), Gaps = 36/240 (15%) Query: 14 LGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY-------SEGQSETILGGLGLRLG 66 LG M G + + A + +G ID A +Y ++G +ET +G + G Sbjct: 18 LGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHG 77 Query: 67 GSDCRVKIDTKAIPLFGNS--LKPD------SLRFQLETSLKRLQCPRVDLFYLHMPDHS 118 + + + P N ++PD ++R L SLKRLQ +DL+ +H P Sbjct: 78 SREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRP 137 Query: 119 T-----------------PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161 T + +TL A + + GK +G+SN A+ V L + Sbjct: 138 TNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHD 197 Query: 162 WILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVG 221 Q Y+ + R E L ++ G+ A++ L G LTGKY NG +P G Sbjct: 198 LPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKY----LNGAKPAG 253 >4JQA-A nrPDB Length = 331 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 15/145 (10%) Query: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79 + P S A+ + +E G ID+A VY+ + GL +R +D VK + Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ----VGLAIRSKIADGSVKREDIFYTS 83 Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139 L+ NS +P+ +R LE SLK LQ VDL+ +H P P EE + + GK + Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKILF 139 Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161 + A WE E C L KS G Sbjct: 140 DTVDLCATWEAMEKCKDAGLAKSIG 164 >4GIE-A nrPDB Length = 290 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 52/191 (27%), Positives = 85/191 (44%), Gaps = 15/191 (7%) Query: 21 RRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGG-SDCRVKIDTKAI 79 R D +A R +E G+ IDTA++YS + G G+R G V + TK Sbjct: 33 RAQDGAETANAVRWAIEAGYRHIDTAYIYSNERG----VGQGIRESGVPREEVWVTTK-- 86 Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139 ++ + + E S + L +DL+ +H P V +T +A +L++E K Sbjct: 87 -VWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPGKKKFV-DTWKALEKLYEEKKVRA 144 Query: 140 LGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199 +G+SN+ + E+ CK I P V Q + + +Q F C +H + A++P Sbjct: 145 IGVSNFEPHHLTELFKSCK----IRPMVNQVELHPLFQQRTLREF-CKQH-NIAITAWSP 198 Query: 200 LAGGLLTGKYK 210 L G G K Sbjct: 199 LGSGEEAGILK 209 >2FVL-A nrPDB Length = 324 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 13/139 (9%) Query: 28 SAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAIPLFGNS 85 + VT+ +E G ID+A++Y+ + GL +R +D VK + L+ Sbjct: 35 AVEVTKLAIEAGFRHIDSAYLYNNEEQ----VGLAIRSKIADGSVKREDIFYTSKLWCTF 90 Query: 86 LKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNY 145 +P ++ LE+SLK+LQ VDL+ LH P P E L + GK + + Sbjct: 91 FQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPK----DENGKVIFDTVDLS 146 Query: 146 AAWEVAEICT---LCKSNG 161 A WEV E C L KS G Sbjct: 147 ATWEVMEKCKDAGLAKSIG 165 >3UP8-A nrPDB Length = 298 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 77/175 (44%), Gaps = 26/175 (14%) Query: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQL 95 L+ G +DTA +Y +E +G + G V + TK ++ ++ + D+ + Sbjct: 57 LKLGFRHVDTAQIYG---NEAEVGEAIQKSGIPRADVFLTTK---VWVDNYRHDAFIASV 110 Query: 96 ETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICT 155 + SL++L+ VDL LH P P+ E + A +++ GK +G+SN+ ++ E Sbjct: 111 DESLRKLRTDHVDLLLLHWPGSDVPMAERIGALNEVRNAGKVRHIGISNFNTTQMEEAAR 170 Query: 156 LCKSNGWILPTVYQGMYNAITRQVE-------TELFPCLRHFGLRFYAFNPLAGG 203 L + P T QVE T++ R G+ ++ +A G Sbjct: 171 LSDA-----PIA--------TNQVEYHPYLDQTKVLQTARRLGMSLTSYYAMANG 212 >3WCZ-A nrPDB Length = 308 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 28/179 (15%) Query: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89 +E G+ IDTA VY + G +E I GL R + + TK L+ + D Sbjct: 45 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTR-----EELFVTTK---LWNDKHARD 96 Query: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141 + L+ SLK+L +DL+ +H P + P + ET + Q G +G Sbjct: 97 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 156 Query: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPL 200 +SN+ A ++ + SN +I P + Q N Q L + G+ A++P Sbjct: 157 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLVAHCQSLGIAVMAYSPF 209 >2BGQ-A nrPDB Length = 344 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 30/210 (14%) Query: 8 ARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL-G 66 A PA LG G + T+ +V A E G+ +DTA Y G + + GL + Sbjct: 47 AMPAVGLGTWRAG----SDTAHSVRTAITEAGYRHVDTAAEY--GVEKEVGKGLKAAMEA 100 Query: 67 GSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------DHSTP 120 G D + T I + +L P+ +R LE +LK LQ +DL+++H P H P Sbjct: 101 GIDRKDLFVTSKI--WCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPP 158 Query: 121 ---------VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGM 171 +E + L ++G ++G+ NY V ++ L +S I P V Q Sbjct: 159 EAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYT---VTKLNRLLRSAK-IPPAVCQME 214 Query: 172 YNAITRQVETELFPCLRHFGLRFYAFNPLA 201 + + ++F + G+ A++PL Sbjct: 215 MHPGWKN--DKIFEACKKHGIHITAYSPLG 242 >4F40-A nrPDB Length = 288 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 45/175 (25%), Positives = 76/175 (43%), Gaps = 21/175 (12%) Query: 39 GHTEIDTAFVYSEGQSETILGGLGLRLGGSDCR-VKIDTKAIPLFGNSLKPDSLRFQLET 97 G+ IDTA +Y +S G GLR G V I TK L+ +S E Sbjct: 48 GYRHIDTAAIYKNEESV----GAGLRASGVPREDVFITTK---LWNTEQGYESTLAAFEE 100 Query: 98 SLKRLQCPRVDLFYLHMPDHSTPVE-------ETLRACHQLHQEGKFVELGLSNYAAWEV 150 S ++L +DL+ +H P + ++ RA QL++E K +G+SN+ + Sbjct: 101 SRQKLGVDYIDLYLIHWPRGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHL 160 Query: 151 AEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLL 205 ++ +C + P V Q + + Q + F + ++ A++PL G L Sbjct: 161 EDVLAMCT----VTPMVNQVELHPLNNQADLRAFCDAKQ--IKVEAWSPLGQGKL 209 >3KRB-A nrPDB Length = 334 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/220 (25%), Positives = 91/220 (41%), Gaps = 40/220 (18%) Query: 15 GAMEMGRRM-----DAPTSAAVT--RAFLERGHTEIDTAFVYSEGQSETILG-GLGLRLG 66 G+M+ R+ AP A T L G+ ID A+VY Q+E +G G Sbjct: 20 GSMQYPPRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVY---QNEEAIGRAFGKIFK 76 Query: 67 GSDCRVKIDTKAI--PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-------- 116 + +K + I L+ + +P+ +R Q + ++ LQ +DLF +H P Sbjct: 77 DASSGIKREDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVG 136 Query: 117 -------------HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWI 163 P+ +T RA QL +EG +G+SNY +A++ K I Sbjct: 137 DLFPKDAEGRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAK----I 192 Query: 164 LPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGG 203 P V Q + T F CL + G+ A++P+ G Sbjct: 193 KPLVNQIEIHPWHPNDATVKF-CLDN-GIGVTAYSPMGGS 230 >1VBJ-A nrPDB Length = 281 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 32/225 (14%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 S +LS VLG M + D + T ++ G+ IDTA +Y ++E G Sbjct: 11 SLKLSNGVMMPVLG-FGMWKLQDGNEAETATMWAIKSGYRHIDTAAIY---KNEESAGRA 66 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 G + + TK L+ + +S E S+K+L VDL+ +H P + Sbjct: 67 IASCGVPREELFVTTK---LWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPGKDKFI 123 Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181 + T +A +L+ + K +G+SN+ + E+ CK + P V Q Sbjct: 124 D-TWKAFEKLYADKKVRAIGVSNFHEHHIEELLKHCK----VAPMVNQ-----------I 167 Query: 182 ELFPCLRHFGLRFY---------AFNPLAGGLLTGKYKYEDKNGK 217 EL P L L Y A++PL G L + + GK Sbjct: 168 ELHPLLNQKALCEYCKSKNIAVTAWSPLGQGHLVEDARLKAIGGK 212 >1Q5M-A nrPDB Length = 322 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 15/145 (10%) Query: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79 + P S A+ T+ ++ G ID+A+ Y + + E GL +R +D VK + Sbjct: 27 EVPKSKAMEATKIAIDAGFRHIDSAYFY-KNEKEV---GLAIRSKIADGTVKREDIFYTS 82 Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139 L+ +P+ +R LE SLK LQ VDL+ +H P P E + + GK + Sbjct: 83 KLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVEIIPT----DEHGKAIF 138 Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161 + A WE E C L KS G Sbjct: 139 DTVDICATWEAMEKCKDAGLAKSIG 163 >5JM5-A nrPDB Length = 332 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 15/145 (10%) Query: 24 DAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79 + P S A VT+ +E G ID+A +Y+ + GL +R +D VK + Sbjct: 28 EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ----VGLAIRSKIADGSVKREDIFYTS 83 Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139 L+ +P+ +R LE SLK+ Q VDL+ +H P P EE + GK + Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEEL----SPTDENGKVIF 139 Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161 + WE E C L KS G Sbjct: 140 DIVDLCTTWEAMEKCKDAGLAKSIG 164 >4HBK-A nrPDB Length = 344 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 48/179 (26%), Positives = 80/179 (44%), Gaps = 33/179 (18%) Query: 4 QLSRARPATVLGAMEMGRRMDAP--TSAAVTRAFLERGHTEIDTAFVY-SEGQ-SETILG 59 +++ R V+G +G P AAV +A LE G+ +D A+VY +E + E + Sbjct: 39 KMNNGRSIPVIG---LGTWNSPPGEVGAAVKKA-LEIGYRHLDCAYVYRNEAEIGEALEN 94 Query: 60 GLG-LRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-- 116 L LRL D + I +K L+ +P+ +R E +LK L+ +DL+ +H P Sbjct: 95 ALNSLRLKRED--IFITSK---LWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPL 149 Query: 117 -----------------HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCK 158 + P E+T + +L EG +GLSN+ ++ I C+ Sbjct: 150 KHGGDLFPTDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCR 208 >2HE8-A nrPDB Length = 323 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 13/145 (8%) Query: 23 MDAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILG-GLGLRLGGSDCRVKIDTKAI 79 ++ P S A +T+ ++ G D+A VY+ +E +G + ++ R + Sbjct: 27 LECPKSKAKELTKIAIDAGFHHFDSASVYN---TEDHVGEAIRSKIADGTVRREDIFYTS 83 Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139 ++ SL P+ +R LE SL++LQ VDL+ +H P P EE + + GK + Sbjct: 84 KVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENF----PVDEHGKLIF 139 Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161 + A WE E C L KS G Sbjct: 140 DRVDLCATWEAMEKCKDAGLTKSIG 164 >1OG6-A nrPDB Length = 298 Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 15/145 (10%) Query: 21 RRMDAPTSAAVTRAFLER----GHTEIDTAFVYSEGQSETILGGLGLRLGG--------- 67 R MD SA +F+E G T +D A +Y Q E G L+L Sbjct: 23 RLMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGE-ALKLAPHLRERMEIV 81 Query: 68 SDCRVKIDTKAIPLFGNSLKP-DSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLR 126 S C + + + G+ + D + E SL L +DL +H PD +E Sbjct: 82 SKCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVAD 141 Query: 127 ACHQLHQEGKFVELGLSNYAAWEVA 151 A LHQ GK G+SN+ + A Sbjct: 142 AFKHLHQSGKVRHFGVSNFTPAQFA 166 >3H7R-A nrPDB Length = 331 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 48/193 (24%), Positives = 89/193 (46%), Gaps = 27/193 (13%) Query: 25 APTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI--PLF 82 A + A+ +A ++ G+ ID A +Y +E +GG+ +L G D VK + I L+ Sbjct: 45 AMVATAIEQA-IKIGYRHIDCASIYG---NEKEIGGVLKKLIG-DGFVKREELFITSKLW 99 Query: 83 GNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDH-------STP-------VEETLRAC 128 N P+ + LE +L+ LQ VDL+ +H P TP + T +A Sbjct: 100 SNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAM 159 Query: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLR 188 L+ GK +G+SN+++ ++ ++ + + + P V Q + + +Q L + Sbjct: 160 EALYDSGKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHELCK 213 Query: 189 HFGLRFYAFNPLA 201 G+ ++PL Sbjct: 214 SKGVHLSGYSPLG 226 >1QWK-A nrPDB Length = 317 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 25/170 (14%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSA-AVTRAFLERGHTEIDTAFVYSEGQSETILGG 60 S +LS V+G +G +P + ++ G+ IDTA VY Q+E +G Sbjct: 7 SIKLSNGVEMPVIG---LGTWQSSPAEVITAVKTAVKAGYRLIDTASVY---QNEEAIGT 60 Query: 61 LGLRLGGSDCRVK-----IDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP 115 ++ + VK I TKA + + L P L L SLK+LQ VDL+ HMP Sbjct: 61 -AIKELLEEGVVKREELFITTKA---WTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMP 116 Query: 116 --------DH-STPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTL 156 +H ++PVE+ R +++ G +G+SN+ +++ L Sbjct: 117 AAFNDDMSEHIASPVEDVWRQFDAVYKAGLAKAVGVSNWNNDQISRALAL 166 >3H7U-A nrPDB Length = 335 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 49/183 (26%), Positives = 83/183 (45%), Gaps = 26/183 (14%) Query: 34 AFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI--PLFGNSLKPDSL 91 A ++ G+ ID A +Y G + I G L+ D VK + I L+ P + Sbjct: 57 AAVKIGYRHIDCAQIY--GNEKEI--GAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDV 112 Query: 92 RFQLETSLKRLQCPRVDLFYLH------------MPDHSTPVE--ETLRACHQLHQEGKF 137 L +LK LQ VDL+ +H P++ PV+ T +A L+ GK Sbjct: 113 PEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKA 172 Query: 138 VELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 +G+SN++ ++A++ L + + P V Q + RQ + + F C + G+ A+ Sbjct: 173 RAIGVSNFSTKKLADLLELAR----VPPAVNQVECHPSWRQTKLQEF-C-KSKGVHLSAY 226 Query: 198 NPL 200 +PL Sbjct: 227 SPL 229 >4R9O-A nrPDB Length = 301 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 15/139 (10%) Query: 21 RRMDAPTSAAVTRAFLER----GHTEIDTAFVYSEGQSETILGGLGLRLGG--------- 67 R MD SA +F+E G T +D A +Y Q E G L L Sbjct: 26 RLMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGE-ALTLAPHLREKLQIV 84 Query: 68 SDCRVKIDTKAIPLFGNSLKPDS-LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLR 126 + C + +A G+ + + E SLK L +D+ +H PD ++ Sbjct: 85 TKCGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPDPLMDADDVAE 144 Query: 127 ACHQLHQEGKFVELGLSNY 145 A LHQ GK G+SN+ Sbjct: 145 AFQHLHQSGKVRHFGVSNF 163 >3D3F-A nrPDB Length = 275 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 44/174 (25%), Positives = 81/174 (46%), Gaps = 13/174 (7%) Query: 32 TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSL 91 +A ++ G+ IDTA +Y + G+G++ G T + + ++ Sbjct: 36 VKAAIKNGYRSIDTAAIYKNEEG----VGIGIKESGVAREELFITSKV--WNEDQGYETT 89 Query: 92 RFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVA 151 E SL+RLQ +DL+ +H P ++T RA +L+++GK +G+SN+ + Sbjct: 90 LAAFEKSLERLQLDYLDLYLIHWPGKDK-YKDTWRALEKLYKDGKIRAIGVSNFQVHHLE 148 Query: 152 EICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLL 205 E+ + I P V Q ++ R + EL + G++ A++PL G L Sbjct: 149 ELL----KDAEIKPMVNQVEFHP--RLTQKELRDYCKGQGIQLEAWSPLMQGQL 196 >4H8N-A nrPDB Length = 310 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 36/229 (15%) Query: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC---RVKIDTKAIPLFGNSLK--PDS 90 L+ G IDTA Y+ + +G L +D + + TK P +G S+K S Sbjct: 53 LKLGFRHIDTAEAYNTQKE------VGEALKRTDVPREDIWVTTKYSPGWG-SIKAYSKS 105 Query: 91 LRFQLETSLKRLQCPRVDLFYLHMP------DHSTPVEETLRACHQLHQEGKFVELGLSN 144 ++ +L +L VDLF +H P H +E+ A + + GK E+G+SN Sbjct: 106 PSDSIDKALAQLGVDYVDLFLIHSPFFTTEQTHGYTLEQAWEALVEAKKAGKVREIGISN 165 Query: 145 YAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGL 204 A + ++ S + P V Q ++ + + + G+ AF+PLA Sbjct: 166 AAIPHLEKLFAASPSPEY-YPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA--- 221 Query: 205 LTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQ 253 P+ R N AE + K E L+ LQ Sbjct: 222 --------------PLARVETNALAETLKRLAEKYKKTEAQVLLRYTLQ 256 >5JH1-A nrPDB Length = 309 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 46/183 (25%), Positives = 82/183 (44%), Gaps = 25/183 (13%) Query: 34 AFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI--PLFGNSLKPDSL 91 A ++ G+ ID A VY G + I GL L+ + VK + I L+ + P+ + Sbjct: 33 AAVKAGYRHIDCARVY--GNEKEI--GLALKKLFEEGVVKREDMFITSKLWNDHHAPEDV 88 Query: 92 RFQLETSLKRLQCPRVDLFYLHMP------------DHSTP-VEETLRACHQLHQEGKFV 138 L SL LQ +DL+ +H P + TP T A +L+ GK Sbjct: 89 PEALNDSLNDLQLEYLDLYLIHWPFRVKKGTNTSPENFVTPDFPATWGAMEKLYDAGKAR 148 Query: 139 ELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFN 198 +G+SN+++ ++ ++ + + + P V Q + +Q T+L + G+ A++ Sbjct: 149 AIGVSNFSSKKLGDLLAVAR----VPPAVDQVECHPGWQQ--TKLHSFCQSTGVHLTAYS 202 Query: 199 PLA 201 PL Sbjct: 203 PLG 205 >1VP5-A nrPDB Length = 298 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 10/116 (8%) Query: 89 DSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAW 148 +S + E SLK+LQ +DL+ +H P V +A +++++G +G+SN+ Sbjct: 100 ESTKKAFEKSLKKLQLEYIDLYLIHQP--FGDVHCAWKAMEEMYKDGLVRAIGVSNFYPD 157 Query: 149 EVAEICTLCKSNGWILPTVYQ-GMYNAITRQVETELFPCLRHFGLRFYAFNPLAGG 203 + ++ + I+P V Q ++ RQ E E +R++ ++ A+ P A G Sbjct: 158 RLMDLMV----HHEIVPAVNQIEIHPFYQRQEEIEF---MRNYNIQPEAWGPFAEG 206 >1MZR-A nrPDB Length = 296 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 50/202 (24%), Positives = 86/202 (42%), Gaps = 33/202 (16%) Query: 30 AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89 A+ +A LE G+ IDTA Y + G+G L + + L+ + K Sbjct: 54 AIQKA-LEVGYRSIDTAAAYKNEE------GVGKALKNASVNREELFITTKLWNDDHK-- 104 Query: 90 SLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVEETLRACHQLHQEGKFVELGLSNY 145 R L SLK+LQ +DL+ +H P DH E + +L +EG +G+ N+ Sbjct: 105 RPREALLDSLKKLQLDYIDLYLMHWPVPAIDHYV---EAWKGMIELQKEGLIKSIGVCNF 161 Query: 146 AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLL 205 ++ + L G + P + Q + + +Q + + ++ +++PLA G Sbjct: 162 ---QIHHLQRLIDETG-VTPVINQIELHPLMQQRQLHAWNATHK--IQTESWSPLAQG-- 213 Query: 206 TGKYKYE--------DKNGKQP 219 GK ++ DK GK P Sbjct: 214 -GKGVFDQKVIRDLADKYGKTP 234 >1MDF-A nrPDB Length = 539 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 22/103 (21%), Positives = 48/103 (46%), Gaps = 6/103 (5%) Query: 89 DSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAW 148 D+ +L ++L + D + +P+ ++E L + G L ++ + Sbjct: 57 DTRADRLAAGFQKLGIQQKDRVVVQLPN----IKEFFEVIFALFRLGALPVFALPSHRSS 112 Query: 149 EVAEICTLCKSNGWILPTVYQGM-YNAITRQVETELFPCLRHF 190 E+ C ++ +I+P Y G Y ++ RQV+++L P L++ Sbjct: 113 EITYFCEFAEAAAYIIPDAYSGFDYRSLARQVQSKL-PTLKNI 154 >4OTK-A nrPDB Length = 318 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 55/188 (29%), Positives = 79/188 (42%), Gaps = 32/188 (17%) Query: 10 PATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSD 69 P LG E+ D T AV+ A LE G IDTA+ Y +E +G G + Sbjct: 58 PVLGLGVAELS---DDETERAVSAA-LEIGCRLIDTAYAYG---NEAAVGRAIAASGVAR 110 Query: 70 CRVKIDTK-AIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRAC 128 + + TK A P G + ++ R SL RL VDL+ +H P + PV + + A Sbjct: 111 EELFVTTKLATPDQGFTRSQEACR----ASLDRLGLDYVDLYLIHWP--APPVGKYVDAW 164 Query: 129 HQLHQ---EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP 185 + Q EG +G+SN+ A + + L ++ P V Q EL P Sbjct: 165 GGMIQSRGEGHARSIGVSNFTAENIENLIDLT----FVTPAVNQ-----------IELHP 209 Query: 186 CLRHFGLR 193 L LR Sbjct: 210 LLNQDELR 217 >5Z6T-A nrPDB Length = 343 Score = 36.6 bits (83), Expect = 0.016, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 25/90 (27%) Query: 81 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------------------------D 116 L+ N PD++ L +L LQ VDLF +H P D Sbjct: 103 LWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFD 162 Query: 117 H-STPVEETLRACHQLHQEGKFVELGLSNY 145 + P+ ET +A +L + GK +G+SN+ Sbjct: 163 YEDVPILETWKALEKLVKAGKIRSIGVSNF 192 >5UXF-A nrPDB Length = 342 Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust. Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 10/108 (9%) Query: 24 DAPTSAAVTRAFL--ERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPL 81 + P S ++ A L + G+ +DTA+ Y E I + + + + L Sbjct: 47 EVPKSKSLEAACLALDVGYRHVDTAYAYQ--VEEEIGQAIQSAIAAGVVKREDLFVTTKL 104 Query: 82 FGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------DHSTPVEE 123 + +P+ ++ LE SLK+LQ VDL+ +H P D+ PV E Sbjct: 105 WCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDFPVNE 152 >4GAC-A nrPDB Length = 324 Score = 35.8 bits (81), Expect = 0.028, Method: Compositional matrix adjust. Identities = 54/222 (24%), Positives = 85/222 (38%), Gaps = 45/222 (20%) Query: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP------ 80 AA+ A L G+ ID A VY G I L +G KA+P Sbjct: 28 VKAAIKHA-LSAGYRHIDCASVY--GNETEIGEALKESVGSG--------KAVPREELFV 76 Query: 81 ---LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------DH-------------S 118 L+ P+ + L +L LQ +DL+ +H P D+ S Sbjct: 77 TSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDS 136 Query: 119 TPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ 178 T +ET +A L +G LGLSN+ + ++ ++ ++ + P V Q + Q Sbjct: 137 THYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVAS----VRPAVLQVECHPYLAQ 192 Query: 179 VETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPV 220 EL GL A++PL ++ E ++PV Sbjct: 193 --NELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPV 232 >2ALR-A nrPDB Length = 324 Score = 35.4 bits (80), Expect = 0.039, Method: Compositional matrix adjust. Identities = 49/202 (24%), Positives = 77/202 (38%), Gaps = 44/202 (21%) Query: 30 AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--------- 80 A + L G+ ID A +Y G I L +G KA+P Sbjct: 30 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPG--------KAVPREELFVTSK 79 Query: 81 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------DH-------------STPV 121 L+ P+ + L +L LQ +DL+ +H P D+ ST Sbjct: 80 LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHY 139 Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181 +ET +A L +G LGLSN+ + ++ +I ++ + P V Q + Q Sbjct: 140 KETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQVECHPYLAQ--N 193 Query: 182 ELFPCLRHFGLRFYAFNPLAGG 203 EL + GL A++PL Sbjct: 194 ELIAHCQARGLEVTAYSPLGSS 215 >1WSA-A nrPDB Length = 330 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 13/130 (10%) Query: 9 RPATVLGAMEMGRRM--DAP------TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60 +P ++GAM G M D P + A+ +A +G + +++ + T L Sbjct: 111 KPVVLVGAMRPGSSMSADGPMNLYNAVNVAINKASTNKGVVIVMNDEIHA-AREATKLNT 169 Query: 61 LGLRLGGSDCRVKIDT---KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDH 117 + S KI T + F S++P +L + + S K + PRVD+ Y H D Sbjct: 170 TAVNAFASPNTGKIGTVYYGKVEYFTQSVRPHTLASEFDIS-KIEELPRVDILYAHPDDT 228 Query: 118 STPVEETLRA 127 V L+A Sbjct: 229 DVLVNAALQA 238 >1HQT-A nrPDB Length = 326 Score = 31.6 bits (70), Expect = 0.51, Method: Compositional matrix adjust. Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 25/142 (17%) Query: 81 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------DHSTP-------------V 121 L+ P+ + L +L LQ +DL+ +H P D+ P Sbjct: 82 LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTIRYDATHY 141 Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181 ++T +A L +G LGLSN+++ ++ ++ ++ + P V Q + Q Sbjct: 142 KDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVAS----VRPAVLQVECHPYLAQ--N 195 Query: 182 ELFPCLRHFGLRFYAFNPLAGG 203 EL + GL A++PL Sbjct: 196 ELIAHCQARGLEVTAYSPLGSS 217 >1AFS-A nrPDB Length = 323 Score = 31.6 bits (70), Expect = 0.56, Method: Compositional matrix adjust. Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 25/143 (17%) Query: 32 TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAIPLFGNSLKPD 89 T+ ++ G D+A++Y E + E G +R D VK + L+ +P+ Sbjct: 38 TKIAIDNGFRHFDSAYLY-EVEEEV---GQAIRSKIEDGTVKREDIFYTSKLWSTFHRPE 93 Query: 90 SLRFQLETSLKRLQCPRVDLFYLHMP-------------DHSTPVEETLRAC------HQ 130 +R LE +LK Q VDL+ +H P +H + ET+ C + Sbjct: 94 LVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIFFPRDEHGKLLFETVDICDTWEAMEK 153 Query: 131 LHQEGKFVELGLSNYAAWEVAEI 153 G +G+SN+ ++ I Sbjct: 154 CKDAGLAKSIGVSNFNCRQLERI 176 >1A80-A nrPDB Length = 277 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 54/205 (26%), Positives = 82/205 (40%), Gaps = 37/205 (18%) Query: 25 APTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGN 84 A T AV A LE G+ IDTA +Y G E + + D + I TK L+ + Sbjct: 26 ADTQRAVEEA-LEVGYRHIDTAAIY--GNEEGVGAAIAASGIARD-DLFITTK---LWND 78 Query: 85 SLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVEL---- 140 D + SL +L +VDL+ +H P T A + +H K +EL Sbjct: 79 RHDGDEPAAAIAESLAKLALDQVDLYLVHWP--------TPAADNYVHAWEKMIELRAAG 130 Query: 141 -----GLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFY 195 G+SN+ V + + + G ++P V Q + +Q E + + + Sbjct: 131 LTRSIGVSNHL---VPHLERIVAATG-VVPAVNQIELHPAYQQREITDWAAAHDVKIESW 186 Query: 196 AFNPLAGGLLTGKYKYEDKNGKQPV 220 G L GKY D G +PV Sbjct: 187 ------GPLGQGKY---DLFGAEPV 202 >1XQ8-A nrPDB Length = 140 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 6/112 (5%) Query: 217 KQPVGRFFGNTW-AEMYRNRYWKEHHFEGIALV-EKALQAAYGASAPSMTSATLRWMYHH 274 KQ V G T +Y KE G+A V EK + +T T Sbjct: 23 KQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTA---VAQ 79 Query: 275 SQLQGAHGDAVILGMSSLEQLEQNLAAA-EEGPLEPAVVDAFNQAWHLVTHE 325 ++GA A G +QL +N A +EG LE VD N+A+ + + E Sbjct: 80 KTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEE 131 >1ITU-A nrPDB Length = 369 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 242 FEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAA 301 F+G+ V + L+ + P + + LR + ++++GA D ++ ++EQ A Sbjct: 289 FDGVPRVPEGLEDV--SKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQA 346 Query: 302 AEEGPL 307 EE P+ Sbjct: 347 PEEEPI 352 >4AZW-A nrPDB Length = 471 Score = 28.1 bits (61), Expect = 5.7, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 16/30 (53%) Query: 109 LFYLHMPDHSTPVEETLRACHQLHQEGKFV 138 FY MP EE+ R H+LH E KF+ Sbjct: 266 FFYYDMPHGILTAEESQRNKHELHNEIKFL 295 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2CLP-A nrPDB 518 e-147 1GVE-A nrPDB 481 e-136 2BP1-A nrPDB 476 e-135 2C91-A nrPDB 475 e-134 3EB3-A nrPDB 293 6e-80 3N6Q-A nrPDB 240 6e-64 1VBJ-A nrPDB 232 2e-61 1PYF-A nrPDB 215 2e-56 4GIE-A nrPDB 209 1e-54 1PZ1-A nrPDB 206 8e-54 3H7U-A nrPDB 199 2e-51 1LQA-A nrPDB 197 6e-51 3H7R-A nrPDB 195 2e-50 4F40-A nrPDB 194 5e-50 4MHB-A nrPDB 190 8e-49 4JQA-A nrPDB 189 2e-48 2BGQ-A nrPDB 188 3e-48 1Q5M-A nrPDB 187 7e-48 5JM5-A nrPDB 184 4e-47 4HBK-A nrPDB 182 2e-46 3KRB-A nrPDB 180 6e-46 3WCZ-A nrPDB 177 7e-45 2FVL-A nrPDB 176 1e-44 3UP8-A nrPDB 174 6e-44 3D3F-A nrPDB 173 1e-43 2HE8-A nrPDB 170 7e-43 1QWK-A nrPDB 163 1e-40 1OG6-A nrPDB 156 1e-38 4R9O-A nrPDB 156 1e-38 Sequences not found previously or not previously below threshold: 5JH1-A nrPDB 188 4e-48 4GAC-A nrPDB 164 3e-41 1VP5-A nrPDB 163 7e-41 1AFS-A nrPDB 162 2e-40 1ZUA-X nrPDB 162 2e-40 2ALR-A nrPDB 161 4e-40 1HQT-A nrPDB 161 5e-40 3G1R-A nrPDB 160 6e-40 5UXF-A nrPDB 159 2e-39 5Z6T-A nrPDB 158 3e-39 1MZR-A nrPDB 155 3e-38 1K8C-A nrPDB 143 1e-34 5ZCM-A nrPDB 141 3e-34 4OTK-A nrPDB 139 1e-33 1DLA-A nrPDB 138 4e-33 3RX4-A nrPDB 137 5e-33 4H8N-A nrPDB 137 5e-33 4IJC-A nrPDB 136 2e-32 1A80-A nrPDB 135 2e-32 1FRB-A nrPDB 128 3e-30 1C9W-A nrPDB 127 5e-30 3O3R-A nrPDB 127 6e-30 3WG6-A nrPDB 126 1e-29 4EXA-A nrPDB 72 4e-13 5J7Z-A nrPDB 30 1.4 3NAF-A nrPDB 30 1.5 3MT5-A nrPDB 30 1.5 3BER-A nrPDB 30 1.8 3UWC-A nrPDB 30 1.8 3U6N-A nrPDB 29 2.3 3Q3N-A nrPDB 29 3.8 5Z1N-A nrPDB 28 4.6 2XY2-A nrPDB 28 5.1 2WIM-A nrPDB 28 5.1 >2CLP-A nrPDB Length = 347 Score = 518 bits (1333), Expect = e-147, Method: Composition-based stats. Identities = 323/326 (99%), Positives = 324/326 (99%) Query: 6 SRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL 65 S ARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL Sbjct: 22 SMARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL 81 Query: 66 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL 125 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL Sbjct: 82 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL 141 Query: 126 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP 185 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP Sbjct: 142 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP 201 Query: 186 CLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGI 245 CLRHFGLRFYAFNPLAGGLLTGKYKYEDK+GKQPVGRFFGNTWAEMYRNRYWKEHHFEGI Sbjct: 202 CLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGI 261 Query: 246 ALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG 305 ALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG Sbjct: 262 ALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG 321 Query: 306 PLEPAVVDAFNQAWHLVTHECPNYFR 331 PLEPAVVDAFNQAWHLV HECPNYFR Sbjct: 322 PLEPAVVDAFNQAWHLVAHECPNYFR 347 >1GVE-A nrPDB Length = 327 Score = 481 bits (1238), Expect = e-136, Method: Composition-based stats. Identities = 264/327 (80%), Positives = 292/327 (89%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLR 64 +S+ARPATVLGAMEMGRRMD +S+A RAFL+RGHTEIDTAFVY+ GQSETILG LGL Sbjct: 1 MSQARPATVLGAMEMGRRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLG 60 Query: 65 LGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEET 124 LG S C+VKI TKA P+FG +LKP +RFQLETSLKRLQCPRVDLFYLH PDH TP+EET Sbjct: 61 LGRSGCKVKIATKAAPMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFPDHGTPIEET 120 Query: 125 LRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELF 184 L+ACHQLHQEGKFVELGLSNY +WEVAEICTLCK NGWI+PTVYQGMYNAITRQVETELF Sbjct: 121 LQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELF 180 Query: 185 PCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEG 244 PCLRHFGLRFYAFNPLAGGLLTG+YKY+DK+GK P RFFGN ++++Y +RYWKE HF G Sbjct: 181 PCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKEEHFNG 240 Query: 245 IALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEE 304 IALVEKAL+ YG +APSM SA +RWMYHHSQL+G GDAVILGMSSLEQLEQNLA EE Sbjct: 241 IALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNLALVEE 300 Query: 305 GPLEPAVVDAFNQAWHLVTHECPNYFR 331 GPLEPAVVDAF+QAW+LV HECPNYFR Sbjct: 301 GPLEPAVVDAFDQAWNLVAHECPNYFR 327 >2BP1-A nrPDB Length = 360 Score = 476 bits (1224), Expect = e-135, Method: Composition-based stats. Identities = 289/335 (86%), Positives = 304/335 (90%), Gaps = 5/335 (1%) Query: 2 SRQLSRARPAT-----VLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSET 56 +R L+ +RP VLG MEMGRRMDAP SAA RAFLERGHTE+DTAF+YS+GQSET Sbjct: 26 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 85 Query: 57 ILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD 116 ILGGLGL LGG DCRVKI TKA P G SLKPDS+R QLETSLKRLQCP+VDLFYLH PD Sbjct: 86 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 145 Query: 117 HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAIT 176 H TPVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMYNA T Sbjct: 146 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 205 Query: 177 RQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRY 236 RQVETELFPCLRHFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFGN+WAE YRNR+ Sbjct: 206 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRF 265 Query: 237 WKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLE 296 WKEHHFE IALVEKALQAAYGASAPS+TSA LRWMYHHSQLQGAHGDAVILGMSSLEQLE Sbjct: 266 WKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 325 Query: 297 QNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR 331 QNLAA EEGPLEPAVVDAFNQAWHLV HECPNYFR Sbjct: 326 QNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR 360 >2C91-A nrPDB Length = 338 Score = 475 bits (1221), Expect = e-134, Method: Composition-based stats. Identities = 275/323 (85%), Positives = 289/323 (89%) Query: 9 RPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGS 68 RPATVLG MEMGRRMDA SAA RAFLERGH+E+DTAF+Y +GQSE ILGGLGL LG Sbjct: 16 RPATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSG 75 Query: 69 DCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRAC 128 DC VKI TKA P G SLKPDS+R QLETSLKRLQCPRVDLFYLH PDHSTPVEETL AC Sbjct: 76 DCTVKIATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAPDHSTPVEETLCAC 135 Query: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLR 188 HQLHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMYNA TRQVE EL PCLR Sbjct: 136 HQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLR 195 Query: 189 HFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALV 248 HFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFGN WAE YRNR+WKEHHFE IALV Sbjct: 196 HFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNNWAETYRNRFWKEHHFEAIALV 255 Query: 249 EKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLE 308 EKALQ YG +AP MTSA LRWMYHHSQLQG GDAVILGMSSLEQLEQNLAA EEGPLE Sbjct: 256 EKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLE 315 Query: 309 PAVVDAFNQAWHLVTHECPNYFR 331 PAVV+AF+QAW++V HECPNYFR Sbjct: 316 PAVVEAFDQAWNMVAHECPNYFR 338 >3EB3-A nrPDB Length = 327 Score = 293 bits (750), Expect = 6e-80, Method: Composition-based stats. Identities = 84/317 (26%), Positives = 143/317 (45%), Gaps = 30/317 (9%) Query: 13 VLGAMEM--GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70 LG G+ D +T A+ + G DTA VY+ G++E +LG + + G Sbjct: 19 GLGTWVTFGGQITDEMAEHLMTLAY-DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRS 77 Query: 71 RVKIDTKAIPLFGNS-------LKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEE 123 + I TK +F L + L+ SL+RLQ VD+ + + PD +TP+EE Sbjct: 78 SLVITTK---IFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEE 134 Query: 124 TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETE 182 T+RA + +G + G S +++ E+ E ++ + I P Q Y+ R+ VE + Sbjct: 135 TVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQ 194 Query: 183 LFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGR--FFGNTWAEMYRNRYWKEH 240 L G+ ++PLA G+++GKY +G P R G W +++ E Sbjct: 195 LPELFHKIGVGAMTWSPLACGIVSGKY----DSGIPPYSRASLKGYQW---LKDKILSEE 247 Query: 241 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 300 A + K LQA ++ + W + + +V+LG S+ EQL +N+ Sbjct: 248 GRRQQAKL-KELQAIAERLGCTLPQLAIAWCLRNEGV-----SSVLLGASNAEQLMENIG 301 Query: 301 AAEEGP-LEPAVVDAFN 316 A + P L ++V + Sbjct: 302 AIQVLPKLSSSIVHEID 318 >3N6Q-A nrPDB Length = 346 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 89/320 (27%), Positives = 132/320 (41%), Gaps = 27/320 (8%) Query: 10 PATVLGAM-EMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSE--GQSETILGGLGLR-L 65 PA LG G + A+ R + G T D A Y G +E G L Sbjct: 26 PALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDF 85 Query: 66 GGSDCRVKIDTKAI-PLF----GNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120 + I TKA ++ G+ L L+ SLKR+ VD+FY H D +TP Sbjct: 86 AAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTP 145 Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180 +EET A Q GK + +G+S+Y+ ++ L + I ++Q YN + R V+ Sbjct: 146 MEETASALAHAVQSGKALYVGISSYSPERTQKMVELLREWK-IPLLIHQPSYNLLNRWVD 204 Query: 181 TE-LFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFF--GNTWAEMYRNRYW 237 L L++ G+ AF PLA GLLTGKY NG R GN + Sbjct: 205 KSGLLDTLQNNGVGCIAFTPLAQGLLTGKY----LNGIPQDSRMHREGNK-VRGLTPKML 259 Query: 238 KEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQ 297 E + + L+ + Q SM L W+ ++ +V++G S EQLE+ Sbjct: 260 TEANLNSLRLLNEMAQ----QRGQSMAQMALSWLLKDDRVT-----SVLIGASRAEQLEE 310 Query: 298 NLAAAEEGPLEPAVVDAFNQ 317 N+ A + +Q Sbjct: 311 NVQALNNLTFSTKELAQIDQ 330 >1VBJ-A nrPDB Length = 281 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 53/216 (24%), Positives = 91/216 (42%), Gaps = 14/216 (6%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 S +LS VLG M + D + T ++ G+ IDTA +Y ++E G Sbjct: 11 SLKLSNGVMMPVLG-FGMWKLQDGNEAETATMWAIKSGYRHIDTAAIY---KNEESAGRA 66 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 G + + TK L+ + +S E S+K+L VDL+ +H P + Sbjct: 67 IASCGVPREELFVTTK---LWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPGKDKFI 123 Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181 +T +A +L+ + K +G+SN+ + E+ CK + P V Q + + Q Sbjct: 124 -DTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKHCK----VAPMVNQIELHPLLNQ--K 176 Query: 182 ELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGK 217 L + + A++PL G L + + GK Sbjct: 177 ALCEYCKSKNIAVTAWSPLGQGHLVEDARLKAIGGK 212 >1PYF-A nrPDB Length = 312 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 82/302 (27%), Positives = 127/302 (42%), Gaps = 28/302 (9%) Query: 8 ARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGG 67 +G + ++ T + R + G T +DTA++Y G+SE ++G + Sbjct: 17 GLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREFNR 76 Query: 68 SDCRVKIDTKAIPL-----FGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE 122 D V I TKA F PD L+ ++ SLKRL +DLFY+H PD TP + Sbjct: 77 ED--VVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFPDEHTPKD 134 Query: 123 ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETE 182 E + A +++ + GK +G+SN++ ++ E +N L V QG YN + R+ E Sbjct: 135 EAVNALNEMKKAGKIRSIGVSNFSLEQLKE------ANKDGLVDVLQGEYNLLNREAEKT 188 Query: 183 LFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHF 242 FP + + F + PL GLL GKY + P G + E Sbjct: 189 FFPYTKEHNISFIPYFPLVSGLLAGKYTE---DTTFPEGDLRNEQ------EHFKGERFK 239 Query: 243 EGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAA 302 E I V K L + L W ++ D +I G +QL N+ A Sbjct: 240 ENIRKVNK-LAPIAEKHNVDIPHIVLAWYLARPEI-----DILIPGAKRADQLIDNIKTA 293 Query: 303 EE 304 + Sbjct: 294 DV 295 >4GIE-A nrPDB Length = 290 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 14/211 (6%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLR 64 L + LG + + R D +A R +E G+ IDTA++YS + +G Sbjct: 18 LHNSVRMPQLG-LGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERG---VGQGIRE 73 Query: 65 LGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEET 124 G V + TK ++ + + E S + L +DL+ +H P V +T Sbjct: 74 SGVPREEVWVTTK---VWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPGKKKFV-DT 129 Query: 125 LRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELF 184 +A +L++E K +G+SN+ + E+ CK I P V Q + + +Q F Sbjct: 130 WKALEKLYEEKKVRAIGVSNFEPHHLTELFKSCK----IRPMVNQVELHPLFQQRTLREF 185 Query: 185 PCLRHFGLRFYAFNPLAGGLLTGKYKYEDKN 215 + + A++PL G G K Sbjct: 186 --CKQHNIAITAWSPLGSGEEAGILKNHVLG 214 >1PZ1-A nrPDB Length = 333 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 77/293 (26%), Positives = 119/293 (40%), Gaps = 30/293 (10%) Query: 13 VLGAMEMGRRM----DAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGS 68 LG +G M D TS RA L++G T IDTA Y GQSE I+G Sbjct: 17 GLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGKAIKEYMKR 76 Query: 69 DCRVKID-----TKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEE 123 D + K LF ++ + + +E SLKRLQ +DL+ +H PD P+EE Sbjct: 77 DQVILATKTALDWKNNQLFRHANRARIVEE-VENSLKRLQTDYIDLYQVHWPDPLVPIEE 135 Query: 124 TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETEL 183 T +L+ GK +G+SN++ ++ + + Q YN R++E + Sbjct: 136 TAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAVAPLH------TIQPPYNLFEREMEESV 189 Query: 184 FPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFE 243 P + + + L GLLTGK E F G+ + ++ K E Sbjct: 190 LPYAKDNKITTLLYGSLCRGLLTGKMTEEYT--------FEGDD-LRNHDPKFQKPRFKE 240 Query: 244 GIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLE 296 ++ V + + A S+ +RW+ D + G QLE Sbjct: 241 YLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPG-----ADIALWGARKPGQLE 288 >3H7U-A nrPDB Length = 335 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 61/313 (19%), Positives = 107/313 (34%), Gaps = 73/313 (23%) Query: 4 QLSRAR--PATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 +L+ P+ LG + + A ++ G+ ID A +Y + G Sbjct: 29 KLNTGAKFPSVGLGTWQASPGLVGDA----VAAAVKIGYRHIDCAQIYGNEKE----IGA 80 Query: 62 GLRLGGSDCRVKIDTK--AIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST 119 L+ D VK + L+ P + L +LK LQ VDL+ +H P Sbjct: 81 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 140 Query: 120 ------------PVE--ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILP 165 PV+ T +A L+ GK +G+SN++ ++A++ L + + P Sbjct: 141 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR----VPP 196 Query: 166 TVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFG 225 V Q + RQ + + F + G+ A++PL G Sbjct: 197 AVNQVECHPSWRQTKLQEF--CKSKGVHLSAYSPLGS---------------------PG 233 Query: 226 NTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAV 285 TW + L L S LRW G +V Sbjct: 234 TTW-------------LKSDVLKNPILNMVAEKLGKSPAQVALRWGLQ-------MGHSV 273 Query: 286 ILGMSSLEQLEQN 298 + ++ ++++N Sbjct: 274 LPKSTNEGRIKEN 286 >1LQA-A nrPDB Length = 346 Score = 197 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 75/330 (22%), Positives = 126/330 (38%), Gaps = 48/330 (14%) Query: 6 SRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY-------SEGQSETIL 58 S LG M G + + A + +G ID A +Y ++G +ET + Sbjct: 10 SLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYV 69 Query: 59 GGLGLRLGGSDCRVKIDTKAIPLFGNS--LKPD------SLRFQLETSLKRLQCPRVDLF 110 G + G + + + P N ++PD ++R L SLKRLQ +DL+ Sbjct: 70 GNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLY 129 Query: 111 YLHMPDHST-----------------PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEI 153 +H P T + +TL A + + GK +G+SN A+ V Sbjct: 130 QVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRY 189 Query: 154 CTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYED 213 L + Q Y+ + R E L ++ G+ A++ L G LTGKY Sbjct: 190 LHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKY---- 245 Query: 214 KNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYH 273 NG +P G NT + RY E + +A A L ++ Sbjct: 246 LNGAKPAGAR--NTLFSRFT-RYSGEQTQKAVA----AYVDIARRHGLDPAQMALAFVRR 298 Query: 274 HSQLQGAHGDAVILGMSSLEQLEQNLAAAE 303 + + +LG ++++QL+ N+ + Sbjct: 299 QPFV-----ASTLLGATTMDQLKTNIESLH 323 >3H7R-A nrPDB Length = 331 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 59/306 (19%), Positives = 107/306 (34%), Gaps = 75/306 (24%) Query: 10 PATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSD 69 P LG M A ++ G+ ID A +Y +E +GG+ +L D Sbjct: 37 PCVGLGTYAM--------VATAIEQAIKIGYRHIDCASIYG---NEKEIGGVLKKL-IGD 84 Query: 70 CRVKIDTK--AIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST-------- 119 VK + L+ N P+ + LE +L+ LQ VDL+ +H P Sbjct: 85 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 144 Query: 120 ------PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYN 173 + T +A L+ GK +G+SN+++ ++ ++ + + + P V Q + Sbjct: 145 EMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECH 200 Query: 174 AITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYR 233 + +Q L + G+ ++PL + G ++ + Sbjct: 201 PVWQQ--QGLHELCKSKGVHLSGYSPLG-------------------SQSKGEVRLKVLQ 239 Query: 234 NRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLE 293 N E + LRW G +V+ SS Sbjct: 240 NPIVTE---------------VAEKLGKTTAQVALRWGLQ-------TGHSVLPKSSSGA 277 Query: 294 QLEQNL 299 +L++NL Sbjct: 278 RLKENL 283 >4F40-A nrPDB Length = 288 Score = 194 bits (493), Expect = 5e-50, Method: Composition-based stats. Identities = 47/220 (21%), Positives = 84/220 (38%), Gaps = 20/220 (9%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLR 64 LS G + + + + + L G+ IDTA +Y ++E +G Sbjct: 15 LSNGVKMPQFG-LGVWQSPAGEVTENAVKWALCAGYRHIDTAAIY---KNEESVGAGLRA 70 Query: 65 LGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-------H 117 G V I TK L+ +S E S ++L +DL+ +H P Sbjct: 71 SGVPREDVFITTK---LWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKDILSKE 127 Query: 118 STPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITR 177 ++ RA QL++E K +G+SN+ + ++ +C + P V Q + + Sbjct: 128 GKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCT----VTPMVNQVELHPLNN 183 Query: 178 QVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGK 217 Q + F + ++ A++PL G L K Sbjct: 184 QADLRAFCDAKQ--IKVEAWSPLGQGKLLSNPILSAIGAK 221 >4MHB-A nrPDB Length = 297 Score = 190 bits (482), Expect = 8e-49, Method: Composition-based stats. Identities = 56/202 (27%), Positives = 89/202 (44%), Gaps = 15/202 (7%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 + +L+ +LG + + + +E G+ IDTA Y Q+ET +G Sbjct: 17 TVKLNNGIAMPLLG-FGVFQMTNTAECERAVIDAIETGYRLIDTAASY---QNETQVGNA 72 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 G + + I TK L+ + + Q E SL RLQ VDL+ +H P V Sbjct: 73 LKLSGIARDELFITTK---LWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQP--YGDV 127 Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181 RA +LHQ GK +G+SN+ +A++ K I+P V Q N +Q+ Sbjct: 128 HGAWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFNK----IIPAVNQIEVNPFNQQLHA 183 Query: 182 ELFPCLRHFGLRFYAFNPLAGG 203 P ++ G++ A+ P A G Sbjct: 184 --VPWMQSRGIQPEAWAPFAEG 203 >4JQA-A nrPDB Length = 331 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 57/225 (25%), Positives = 84/225 (37%), Gaps = 36/225 (16%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILGG 60 +L+ VLG + P S A + +E G ID+A VY+ + G Sbjct: 8 VKLNDGHFMPVLGFGTYAPA-EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ----VG 62 Query: 61 LGLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHS 118 L +R +D VK + L+ NS +P+ +R LE SLK LQ VDL+ +H P Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122 Query: 119 TPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICT---LCKSNGW------------- 162 P EE + + GK + + A WE E C L KS G Sbjct: 123 KPGEEVIPK----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178 Query: 163 -----ILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 P Q + Q +L + + A++ L Sbjct: 179 KPGLKYKPVCNQVECHPYFNQR--KLLDFCKSKDIVLVAYSALGS 221 >2BGQ-A nrPDB Length = 344 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 57/313 (18%), Positives = 107/313 (34%), Gaps = 74/313 (23%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLG 62 + A PA LG G + T+ +V A E G+ +DTA Y + Sbjct: 42 LKSGHAMPAVGLGTWRAG----SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAA 97 Query: 63 LRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST--- 119 + G + + +K ++ +L P+ +R LE +LK LQ +DL+++H P Sbjct: 98 MEAGIDRKDLFVTSK---IWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA 154 Query: 120 ------------PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTV 167 +E + L ++G ++G+ NY ++ + K I P V Sbjct: 155 HMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAK----IPPAV 210 Query: 168 YQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNT 227 Q + + ++F + G+ A++PL Sbjct: 211 CQMEMHPGWKN--DKIFEACKKHGIHITAYSPLGS------------------------- 243 Query: 228 WAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVIL 287 E + +VEK + ++W G +VI Sbjct: 244 ----------SEKNLAHDPVVEKVANKLNKTPGQVL----IKWALQ-------RGTSVIP 282 Query: 288 GMSSLEQLEQNLA 300 S E++++N+ Sbjct: 283 KSSKDERIKENIQ 295 >5JH1-A nrPDB Length = 309 Score = 188 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 60/311 (19%), Positives = 108/311 (34%), Gaps = 70/311 (22%) Query: 5 LSRARPATVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGL 63 L+ +G +G P A ++ G+ ID A VY + GL L Sbjct: 6 LNTGAKIPSVG---LGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKE----IGLAL 58 Query: 64 RLGGSDCRVKIDTK--AIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 + + VK + L+ + P+ + L SL LQ +DL+ +H P Sbjct: 59 KKLFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKG 118 Query: 122 EE-------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVY 168 T A +L+ GK +G+SN+++ ++ ++ + + + P V Sbjct: 119 TNTSPENFVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVAR----VPPAVD 174 Query: 169 QGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTW 228 Q + +Q T+L + G+ A++PL G TW Sbjct: 175 QVECHPGWQQ--TKLHSFCQSTGVHLTAYSPLGS---------------------PGTTW 211 Query: 229 AEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILG 288 G L E + + + LRW G +V+ Sbjct: 212 -------------MNGNVLKEPIIISIAEKLGKTSAQVALRWNIQ-------MGHSVLPK 251 Query: 289 MSSLEQLEQNL 299 ++ E+++QNL Sbjct: 252 STNEERIKQNL 262 >1Q5M-A nrPDB Length = 322 Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats. Identities = 71/356 (19%), Positives = 124/356 (34%), Gaps = 75/356 (21%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGG 60 LS VLG + P S A+ T+ ++ G ID+A+ Y + G Sbjct: 7 VALSDGHFIPVLGFGTYAPE-EVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKE----VG 61 Query: 61 LGLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHS 118 L +R +D VK + L+ +P+ +R LE SLK LQ VDL+ +H P Sbjct: 62 LAIRSKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTAL 121 Query: 119 TPVEE-------------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKS 159 P E T A + G +G+SN+ ++ I K Sbjct: 122 KPGVEIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN--KP 179 Query: 160 NGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQP 219 P Q + Q +L + G+ A++ L + ++P Sbjct: 180 GLKYKPVCNQVECHPYLNQG--KLLEFCKSKGIVLVAYSALG-------------SHREP 224 Query: 220 VGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQG 279 W + ++ +A + + LR+ Sbjct: 225 E-------WVDQSAPVLLEDPLIGALAKKHQ----------QTPALIALRYQLQ------ 261 Query: 280 AHGDAVILGMSSLEQLEQNLAAAE-EGPLEP-AVVDAFNQAWHLVTHEC----PNY 329 G V+ + +++++N+ E + P E V+D+ N+ + VT + PNY Sbjct: 262 -RGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYVTADFAIGHPNY 316 >5JM5-A nrPDB Length = 332 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 51/223 (22%), Positives = 84/223 (37%), Gaps = 32/223 (14%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILGG 60 +L+ VLG + P S A VT+ +E G ID+A +Y+ + G Sbjct: 8 VKLNDGHFMPVLGFGTYAPP-EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ----VG 62 Query: 61 LGLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHS 118 L +R +D VK + L+ +P+ +R LE SLK+ Q VDL+ +H P Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122 Query: 119 TPVEE-------------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKS 159 P EE T A + G +G+SN+ ++ I K Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN--KP 180 Query: 160 NGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 P Q + + ++L + + A++ L Sbjct: 181 GLKYKPVCNQVECHPYFNR--SKLLDFCKSKDIVLVAYSALGS 221 >4HBK-A nrPDB Length = 344 Score = 182 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 50/221 (22%), Positives = 84/221 (38%), Gaps = 33/221 (14%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSA-AVTRAFLERGHTEIDTAFVYSEG-QSETILGG 60 +++ R V+G +G P A + LE G+ +D A+VY + L Sbjct: 38 LKMNNGRSIPVIG---LGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALEN 94 Query: 61 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST- 119 L + I +K L+ +P+ +R E +LK L+ +DL+ +H P Sbjct: 95 ALNSLRLKREDIFITSK---LWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKH 151 Query: 120 ------------------PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161 P E+T + +L EG +GLSN+ ++ I C+ Sbjct: 152 GGDLFPTDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCR--- 208 Query: 162 WILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 I P Q +A + +L + GL A+ PL Sbjct: 209 -IKPANLQIEIHANFPNI--KLVEYAQSVGLTVTAYAPLGS 246 >3KRB-A nrPDB Length = 334 Score = 180 bits (457), Expect = 6e-46, Method: Composition-based stats. Identities = 65/312 (20%), Positives = 104/312 (33%), Gaps = 63/312 (20%) Query: 17 MEMGRRMDAPTSA-AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKID 75 + G P + L G+ ID A+VY E I G + +K + Sbjct: 28 LGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNE--EAIGRAFGKIFKDASSGIKRE 85 Query: 76 TKA--IPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------------------ 115 L+ + +P+ +R Q + ++ LQ +DLF +H P Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 116 ---DHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMY 172 P+ +T RA QL +EG +G+SNY +A++ K I P V Q Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAK----IKPLVNQIEI 201 Query: 173 NAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMY 232 + T F G+ A++P+ G D +G Q Sbjct: 202 HPWHPNDATVKFCL--DNGIGVTAYSPMGGSY----ADPRDPSGTQ-------------- 241 Query: 233 RNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSL 292 + + L K L+A A S L W H + +VI + Sbjct: 242 ----------KNVILECKTLKAIADAKGTSPHCVALAW---HVKKWNTSMYSVIPKSQTP 288 Query: 293 EQLEQNLAAAEE 304 ++E N E Sbjct: 289 ARIEANFKCTEV 300 >3WCZ-A nrPDB Length = 308 Score = 177 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 54/230 (23%), Positives = 89/230 (38%), Gaps = 38/230 (16%) Query: 7 RARPATVLGAMEMGRRMDAPTSAAVTR---AFLERGHTEIDTAFVYSEGQS------ETI 57 P LG G ++ + V + +E G+ IDTA VY + + E I Sbjct: 14 NTIPIVALGTGR-GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 72 Query: 58 LGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDH 117 GL R + + TK L+ + D + L+ SLK+L +DL+ +H P Sbjct: 73 ANGLVTR-----EELFVTTK---LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 124 Query: 118 STPVE--------ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169 + P + ET + Q G +G+SN+ A ++ + SN +I P + Q Sbjct: 125 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV----SNSYIRPVINQ 180 Query: 170 GMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQP 219 N Q L + G+ A++P + G+ G P Sbjct: 181 IEVNPTNTQ--EPLVAHCQSLGIAVMAYSPFGFVVSRGQ------TGAPP 222 >2FVL-A nrPDB Length = 324 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 34/223 (15%) Query: 3 RQLSRARPATVLGAMEM-GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 +L+ VLG + + VT+ +E G ID+A++Y+ + GL Sbjct: 9 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ----VGL 64 Query: 62 GLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST 119 +R +D VK + L+ +P ++ LE+SLK+LQ VDL+ LH P Sbjct: 65 AIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALK 124 Query: 120 PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICT---LCKSNGW-------------- 162 P E L + GK + + A WEV E C L KS G Sbjct: 125 PGETPLPK----DENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNK 180 Query: 163 ----ILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLA 201 P Q + Q ++L + + A + L Sbjct: 181 PGLKYKPVCNQVECHPYLNQ--SKLLDFCKSKDIVLVAHSALG 221 >3UP8-A nrPDB Length = 298 Score = 174 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 46/212 (21%), Positives = 86/212 (40%), Gaps = 14/212 (6%) Query: 6 SRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRL 65 S LG RM + L+ G +DTA +Y +E +G + Sbjct: 29 SNGANIPALGFGTF--RMSGAEVLRILPQALKLGFRHVDTAQIYG---NEAEVGEAIQKS 83 Query: 66 GGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETL 125 G V + TK ++ ++ + D+ ++ SL++L+ VDL LH P P+ E + Sbjct: 84 GIPRADVFLTTK---VWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWPGSDVPMAERI 140 Query: 126 RACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFP 185 A +++ GK +G+SN+ ++ E L + Q Y+ Q T++ Sbjct: 141 GALNEVRNAGKVRHIGISNFNTTQMEEAARLSDA----PIATNQVEYHPYLDQ--TKVLQ 194 Query: 186 CLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGK 217 R G+ ++ +A G + + G+ Sbjct: 195 TARRLGMSLTSYYAMANGKVPADPLLTEIGGR 226 >3D3F-A nrPDB Length = 275 Score = 173 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 47/204 (23%), Positives = 93/204 (45%), Gaps = 14/204 (6%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 + +L G + + + + + +A ++ G+ IDTA +Y ++E +G Sbjct: 7 TVKLHNGVEMPWFG-LGVFKVENGNEATESVKAAIKNGYRSIDTAAIY---KNEEGVGIG 62 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 G + + I +K ++ ++ E SL+RLQ +DL+ +H P Sbjct: 63 IKESGVAREELFITSK---VWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK-Y 118 Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181 ++T RA +L+++GK +G+SN+ + E+ + I P V Q ++ R + Sbjct: 119 KDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLK----DAEIKPMVNQVEFHP--RLTQK 172 Query: 182 ELFPCLRHFGLRFYAFNPLAGGLL 205 EL + G++ A++PL G L Sbjct: 173 ELRDYCKGQGIQLEAWSPLMQGQL 196 >2HE8-A nrPDB Length = 323 Score = 170 bits (431), Expect = 7e-43, Method: Composition-based stats. Identities = 50/220 (22%), Positives = 85/220 (38%), Gaps = 32/220 (14%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILGGLG 62 L+ VLG ++ P S A +T+ ++ G D+A VY+ +E +G Sbjct: 10 LNDGNFIPVLG-FGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYN---TEDHVGE-A 64 Query: 63 LRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120 +R +D V+ + ++ SL P+ +R LE SL++LQ VDL+ +H P P Sbjct: 65 IRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKP 124 Query: 121 VEE-------------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161 EE T A + G +G+SN+ ++ I K Sbjct: 125 GEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILN--KPGL 182 Query: 162 WILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLA 201 P Q + Q+ +L + + A+ L Sbjct: 183 KYKPVCNQVECHPYLNQM--KLLDFCKSKDIVLVAYGVLG 220 >4GAC-A nrPDB Length = 324 Score = 164 bits (416), Expect = 3e-41, Method: Composition-based stats. Identities = 73/345 (21%), Positives = 117/345 (33%), Gaps = 74/345 (21%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTS-AAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60 S L + ++G +G P A + L G+ ID A VY +ET +G Sbjct: 4 SVLLHTGQKMPLIG---LGTWKSEPGQVKAAIKHALSAGYRHIDCASVYG---NETEIGE 57 Query: 61 LGLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP--- 115 GS V + L+ P+ + L +L LQ +DL+ +H P Sbjct: 58 ALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 117 Query: 116 ---DHSTP-------------VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKS 159 D+ P +ET +A L +G LGLSN+ + ++ ++ ++ Sbjct: 118 ERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVA-- 175 Query: 160 NGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQP 219 + P V Q + Q E L GL A++PL Sbjct: 176 --SVRPAVLQVECHPYLAQNE--LIAHCHARGLEVTAYSPLGSS---------------- 215 Query: 220 VGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQG 279 +R W+ H E + L E + A S LRW Q Sbjct: 216 --------------DRAWR-HPDEPVLLEEPVVLALAEKHGRSPAQILLRW-------QV 253 Query: 280 AHGDAVILGMSSLEQLEQNLAAAE--EGPLEPAVVDAFNQAWHLV 322 I + ++ QN+ + P E +DA N+ W + Sbjct: 254 QRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYI 298 >1VP5-A nrPDB Length = 298 Score = 163 bits (413), Expect = 7e-41, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 87/204 (42%), Gaps = 22/204 (10%) Query: 5 LSRARPATVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGL 63 L+ +LG G P + ++ G+ IDTA Y +E +G Sbjct: 20 LNNGVEMPILG---YGVFQIPPEKTEECVYEAIKVGYRLIDTAASY---MNEEGVGRAIK 73 Query: 64 RLGG----SDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST 119 R + + TK L+ + + +S + E SLK+LQ +DL+ +H P Sbjct: 74 RAIDEGIVRREELFVTTK---LWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP--FG 128 Query: 120 PVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQV 179 V +A +++++G +G+SN+ + ++ + I+P V Q + ++ Sbjct: 129 DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLM----VHHEIVPAVNQIEIHPFYQRQ 184 Query: 180 ETELFPCLRHFGLRFYAFNPLAGG 203 E F +R++ ++ A+ P A G Sbjct: 185 EEIEF--MRNYNIQPEAWGPFAEG 206 >1QWK-A nrPDB Length = 317 Score = 163 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 29/215 (13%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSA-AVTRAFLERGHTEIDTAFVYSEGQSETILGG 60 S +LS V+G +G +P + ++ G+ IDTA VY Q+E +G Sbjct: 7 SIKLSNGVEMPVIG---LGTWQSSPAEVITAVKTAVKAGYRLIDTASVY---QNEEAIGT 60 Query: 61 LGLRLGGS----DCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD 116 L + I TKA + + L P L L SLK+LQ VDL+ HMP Sbjct: 61 AIKELLEEGVVKREELFITTKA---WTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPA 117 Query: 117 H---------STPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTV 167 ++PVE+ R +++ G +G+SN+ +++ L G Sbjct: 118 AFNDDMSEHIASPVEDVWRQFDAVYKAGLAKAVGVSNWNNDQISRALAL----GLTPVHN 173 Query: 168 YQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 Q + Q + + + ++ L Sbjct: 174 SQVELHLYFPQHDH--VDFCKKHNISVTSYATLGS 206 >1AFS-A nrPDB Length = 323 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 40/225 (17%), Positives = 77/225 (34%), Gaps = 30/225 (13%) Query: 1 MSRQLSRARPATVLG-AMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILG 59 + L+ VLG + ++ T+ ++ G D+A++Y + Sbjct: 6 LRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEE----V 61 Query: 60 GLGLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDH 117 G +R D VK + L+ +P+ +R LE +LK Q VDL+ +H P Sbjct: 62 GQAIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMA 121 Query: 118 STPVE-------------------ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCK 158 P + +T A + G +G+SN+ ++ I K Sbjct: 122 LQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILN--K 179 Query: 159 SNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGG 203 P Q + Q +++ + + ++ L Sbjct: 180 PGLKYKPVCNQVECHLYLNQ--SKMLDYCKSKDIILVSYCTLGSS 222 >1ZUA-X nrPDB Length = 317 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 77/215 (35%), Gaps = 33/215 (15%) Query: 9 RPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGS 68 P LG + + ++ G+ ID A+VY Q+E +G ++ Sbjct: 14 MPIVGLGTWKSP----LGKVKEAVKVAIDAGYRHIDCAYVY---QNEHEVGE-AIQEKIQ 65 Query: 69 DCRVKIDTKA--IPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE---- 122 + VK + L+ + +R E +LK L+ +D++ +H P + Sbjct: 66 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 125 Query: 123 ---------------ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTV 167 + A +L EG LG+SN++ +++ ++ K P Sbjct: 126 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN--KPGLKYKPVT 183 Query: 168 YQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 Q + Q +L G+ A++PL Sbjct: 184 NQVECHPYLTQ--EKLIQYCHSKGITVTAYSPLGS 216 >2ALR-A nrPDB Length = 324 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 67/342 (19%), Positives = 116/342 (33%), Gaps = 74/342 (21%) Query: 5 LSRARPATVLGAMEMGRRMDAPTS-AAVTRAFLERGHTEIDTAFVYSEG--QSETILGGL 61 L + ++G +G P A + L G+ ID A +Y E + + Sbjct: 7 LHTGQKMPLIG---LGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDV 63 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------ 115 G + + +K L+ P+ + L +L LQ +DL+ +H P Sbjct: 64 GPGKAVPREELFVTSK---LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120 Query: 116 DHSTP-------------VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGW 162 D+ P +ET +A L +G LGLSN+ + ++ +I ++ Sbjct: 121 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS---- 176 Query: 163 ILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGR 222 + P V Q + Q E L + GL A++PL Sbjct: 177 VRPAVLQVECHPYLAQNE--LIAHCQARGLEVTAYSPLGSS------------------- 215 Query: 223 FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHG 282 +R W++ E + L E + A S LRW Q Sbjct: 216 -----------DRAWRDPD-EPVLLEEPVVLALAEKYGRSPAQILLRW-------QVQRK 256 Query: 283 DAVILGMSSLEQLEQNLAAAE--EGPLEPAVVDAFNQAWHLV 322 I + ++ QN+ + P E ++A N+ W + Sbjct: 257 VICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 298 >1HQT-A nrPDB Length = 326 Score = 161 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 56/288 (19%), Positives = 101/288 (35%), Gaps = 65/288 (22%) Query: 5 LSRARPATVLGAMEMGRRMDAPTS-AAVTRAFLERGHTEIDTAFVYSEG--QSETILGGL 61 L + ++G +G P A + L G+ ID A ++ E + + Sbjct: 9 LHTGQKMPLIG---LGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQETV 65 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------ 115 G + + +K L+ P+ + L +L LQ +DL+ +H P Sbjct: 66 GPGKAVPREELFVTSK---LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 122 Query: 116 DHSTP-------------VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGW 162 D+ P ++T +A L +G LGLSN+++ ++ ++ ++ Sbjct: 123 DNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVAS---- 178 Query: 163 ILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGR 222 + P V Q + Q E L + GL A++PL Sbjct: 179 VRPAVLQVECHPYLAQNE--LIAHCQARGLEVTAYSPLGSS------------------- 217 Query: 223 FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRW 270 +R W++ + E + L E +QA S LRW Sbjct: 218 -----------DRAWRDPN-EPVLLEEPVVQALAEKYNRSPAQILLRW 253 >3G1R-A nrPDB Length = 346 Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats. Identities = 55/315 (17%), Positives = 103/315 (32%), Gaps = 66/315 (20%) Query: 7 RARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLG 66 + P LG + A + ++ G+ ID A++Y Q+E +G +R Sbjct: 36 NSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIY---QNEHEVGE-AIREK 91 Query: 67 GSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEE- 123 ++ +V+ + L+ + P+ +R LE +L+ LQ VDL+ + +P P +E Sbjct: 92 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 151 Query: 124 ------------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILP 165 T A G LG+SN+ ++ L K P Sbjct: 152 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLE--LILNKPGLKHKP 209 Query: 166 TVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFG 225 Q + Q +L + + A++PL + P+ Sbjct: 210 VSNQVECHPYFTQP--KLLKFCQQHDIVITAYSPLGTS-------------RNPI----- 249 Query: 226 NTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAV 285 W + K+ + + LR+ G V Sbjct: 250 --WVNVSSPPLLKDALLNSLGK----------RYNKTAAQIVLRFNIQ-------RGVVV 290 Query: 286 ILGMSSLEQLEQNLA 300 I +LE++++N Sbjct: 291 IPKSFNLERIKENFQ 305 >5UXF-A nrPDB Length = 342 Score = 159 bits (402), Expect = 2e-39, Method: Composition-based stats. Identities = 47/239 (19%), Positives = 83/239 (34%), Gaps = 36/239 (15%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSAAVTRA--FLERGHTEIDTAFVYSEGQSETILGG 60 +L+ LG + + P S ++ A L+ G+ +DTA+ Y Q E +G Sbjct: 27 VKLNDGHLIPALG-FGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAY---QVEEEIG- 81 Query: 61 LGLRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHS 118 ++ + VK + L+ +P+ ++ LE SLK+LQ VDL+ +H P Sbjct: 82 QAIQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPM 141 Query: 119 TPVE-------------------ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKS 159 + +T + G +G+SN+ ++ I K Sbjct: 142 KSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILN--KP 199 Query: 160 NGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQ 218 P Q + Q +L + A+ L T +YK Sbjct: 200 GLKYKPVCNQVECHLYLNQR--KLLDYCESKDIVLVAYGALG----TQRYKEWVDQNSP 252 >5Z6T-A nrPDB Length = 343 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 60/325 (18%), Positives = 107/325 (32%), Gaps = 75/325 (23%) Query: 2 SRQLSRARPATVLGAMEMGRR-MDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60 S +L+ +G G +D T + ++ G+ D A Y+ + L G Sbjct: 28 SIKLNSGYDMPAVG---FGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEK----LVG 80 Query: 61 LGLRLGGSDCRVKIDTK--AIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-- 116 G++ + VK + L+ N PD++ L +L LQ VDLF +H P Sbjct: 81 AGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTF 140 Query: 117 -----------------------HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEI 153 P+ ET +A +L + GK +G+SN+ + ++ Sbjct: 141 KFVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDL 200 Query: 154 CTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYED 213 I P+V Q ++ +Q L + G+ A++ + Sbjct: 201 LRGAT----IKPSVLQVEHHPYLQQP--RLIEFAQSRGIAVTAYSSFGPQSFVELNQGRA 254 Query: 214 KNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYH 273 N F N + ++A S LRW Sbjct: 255 LNTSP----LFEN-----------------------ETIKAIAAKHGKSPAQVLLRW--- 284 Query: 274 HSQLQGAHGDAVILGMSSLEQLEQN 298 G A+I +++ +L +N Sbjct: 285 ----SSQRGIAIIPKSNTVPRLLEN 305 >1OG6-A nrPDB Length = 298 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 60/272 (22%), Positives = 95/272 (34%), Gaps = 53/272 (19%) Query: 17 MEMGRRMDAPTSAAVTRAFLER----GHTEIDTAFVYSEGQSETILGGLGLRLGG----- 67 M R MD SA +F+E G T +D A +Y Q E G L+L Sbjct: 19 MGYWRLMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGE-ALKLAPHLRER 77 Query: 68 ----SDCRVKIDTKAIPLFGNSLK-PDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE 122 S C + + + G+ + D + E SL L +DL +H PD + Sbjct: 78 MEIVSKCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDAD 137 Query: 123 ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITR-QVET 181 E A LHQ GK G+SN+ + A L +S Q + + + + Sbjct: 138 EVADAFKHLHQSGKVRHFGVSNFTPAQFA----LLQSRLPFTLATNQVEISPVHQPLLLD 193 Query: 182 ELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHH 241 L+ +R A++ L GG R F + + + R+ Sbjct: 194 GTLDQLQQLRVRPMAWSCLGGG------------------RLFNDDYFQPLRDE------ 229 Query: 242 FEGIALVEKALQAAYGASAPSMTSATLRWMYH 273 +A+V + L A S+ W+ Sbjct: 230 ---LAVVAEELNAG------SIEQVVNAWVLR 252 >4R9O-A nrPDB Length = 301 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 78/212 (36%), Gaps = 18/212 (8%) Query: 17 MEMGRRMDAPTSAAVTRAFLER----GHTEIDTAFVYSEGQSETILGGLG-----LRLG- 66 M R MD SA +F+E G T +D A +Y Q E G LR Sbjct: 22 MGYWRLMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTLAPHLREKL 81 Query: 67 --GSDCRVKIDTKAIPLFGNSLK-PDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEE 123 + C + +A G+ + + E SLK L +D+ +H PD ++ Sbjct: 82 QIVTKCGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPDPLMDADD 141 Query: 124 TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITR-QVETE 182 A LHQ GK G+SN+ + L +S Q + + + + Sbjct: 142 VAEAFQHLHQSGKVRHFGVSNFTPAQFT----LLQSRLPFTLATNQVEISPVHQPLLLDG 197 Query: 183 LFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDK 214 L+ +R A++ L GG L Y+ Sbjct: 198 TLDQLQQLRIRPMAWSCLGGGRLFNDEAYQPL 229 >1MZR-A nrPDB Length = 296 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 44/203 (21%), Positives = 80/203 (39%), Gaps = 19/203 (9%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSA-AVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 +L LG +G + + LE G+ IDTA Y ++E +G Sbjct: 28 IKLQDGNVMPQLG---LGVWQASNEEVITAIQKALEVGYRSIDTAAAY---KNEEGVGKA 81 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 + + I TK L+ + K R L SLK+LQ +DL+ +H P + Sbjct: 82 LKNASVNREELFITTK---LWNDDHKRP--REALLDSLKKLQLDYIDLYLMHWPVPAIDH 136 Query: 122 -EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180 E + +L +EG +G+ N+ + + + P + Q + + +Q Sbjct: 137 YVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLI----DETGVTPVINQIELHPLMQQR- 191 Query: 181 TELFPCLRHFGLRFYAFNPLAGG 203 +L ++ +++PLA G Sbjct: 192 -QLHAWNATHKIQTESWSPLAQG 213 >1K8C-A nrPDB Length = 322 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 43/226 (19%), Positives = 79/226 (34%), Gaps = 39/226 (17%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLG 62 +LS +G + +A T+ ++ G+ D A Y + G G Sbjct: 8 IKLSSGHLMPSIG-FGCWKLANA-TAGEQVYQAIKAGYRLFDGAEDYGNEKE----VGDG 61 Query: 63 LRLGGSDCRVKIDT--KAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD---- 116 ++ + VK + L+ N P ++ L +L L+ VDLF +H P Sbjct: 62 VKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKF 121 Query: 117 ---------------------HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICT 155 P+ ET +A +L GK +G+SN+ + ++ Sbjct: 122 VPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLR 181 Query: 156 LCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLA 201 I P V Q ++ +Q +L + G+ A++ Sbjct: 182 GAT----IKPAVLQVEHHPYLQQP--KLIEFAQKAGVTITAYSSFG 221 >5ZCM-A nrPDB Length = 341 Score = 141 bits (356), Expect = 3e-34, Method: Composition-based stats. Identities = 44/228 (19%), Positives = 84/228 (36%), Gaps = 39/228 (17%) Query: 1 MSRQLSRARPATVLGAMEMGRR-MDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILG 59 MS +L+ ++G G +D T A ++ G+ D A Y + Sbjct: 22 MSIKLNSGYEMPLVG---FGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGI 78 Query: 60 GLGLRLG-GSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-- 116 L G + + I +K L+ + P ++ L+ L ++ +DLF +H P Sbjct: 79 NRALDEGLVARDELFITSK---LWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAF 135 Query: 117 -----------------------HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEI 153 P+ ET +A +L + GK +G+SN++A + ++ Sbjct: 136 KFVPFEEKYPPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDL 195 Query: 154 CTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLA 201 I P V Q ++ +Q L ++ G+ A++ Sbjct: 196 LRGA----EIKPAVLQIEHHPYLQQP--RLIEYVQSQGIAITAYSSFG 237 >4OTK-A nrPDB Length = 318 Score = 139 bits (351), Expect = 1e-33, Method: Composition-based stats. Identities = 50/205 (24%), Positives = 75/205 (36%), Gaps = 15/205 (7%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 S L+ VLG + + D T A A LE G IDTA+ Y +E +G Sbjct: 48 SITLNDEHTMPVLG-LGVAELSDDETERA-VSAALEIGCRLIDTAYAYG---NEAAVGRA 102 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHST-P 120 G + + + TK L + SL RL VDL+ +H P Sbjct: 103 IAASGVAREELFVTTK---LATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPAPPVGK 159 Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180 + Q EG +G+SN+ A + + L ++ P V Q + + Q E Sbjct: 160 YVDAWGGMIQSRGEGHARSIGVSNFTAENIENLIDLT----FVTPAVNQIELHPLLNQDE 215 Query: 181 TELFPCLRHFGLRFYAFNPLAGGLL 205 + ++ PLA G L Sbjct: 216 LRKANA--QHTVVTQSYCPLALGRL 238 >1DLA-A nrPDB Length = 314 Score = 138 bits (347), Expect = 4e-33, Method: Composition-based stats. Identities = 47/220 (21%), Positives = 80/220 (36%), Gaps = 33/220 (15%) Query: 5 LSRARPATVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGL 63 L +LG +G P + ++ G+ ID A VY GLGL Sbjct: 5 LYTGAKMPILG---LGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENE----VGLGL 57 Query: 64 RLGGSDCRVKIDTKA--IPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 + VK + L+ + + ++ +T+L+ L+ +DL+ +H P P Sbjct: 58 QEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPG 117 Query: 122 E-------------------ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGW 162 + ET A +L EG +G+SN+ +V +I K Sbjct: 118 KDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILN--KPGLK 175 Query: 163 ILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 P V Q + Q +L + G+ A++PL Sbjct: 176 YKPAVNQIEVHPYLTQ--EKLIEYCKSKGIVVTAYSPLGS 213 >3RX4-A nrPDB Length = 336 Score = 137 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 43/220 (19%), Positives = 77/220 (35%), Gaps = 33/220 (15%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSA-AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGL 63 L+ +LG +G P + ++ G+ ID A VY G+ + Sbjct: 27 LNNGAKMPILG---LGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENE----VGVAI 79 Query: 64 RLGGSDCRVKIDTKA--IPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPV 121 + + VK + L+ + ++ + +L L+ +DL+ +H P P Sbjct: 80 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 139 Query: 122 EE-------------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGW 162 +E T A +L EG +G+SN+ +V I K Sbjct: 140 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN--KPGLK 197 Query: 163 ILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 P V Q + Q +L + G+ A++PL Sbjct: 198 YKPAVNQIECHPYLTQ--EKLIQYCQSKGIVVTAYSPLGS 235 >4H8N-A nrPDB Length = 310 Score = 137 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 51/225 (22%), Positives = 85/225 (37%), Gaps = 28/225 (12%) Query: 36 LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRF-Q 94 L+ G IDTA Y+ ++ +G R + + TK P +G+ Sbjct: 53 LKLGFRHIDTAEAYN---TQKEVGEALKRTDVPREDIWVTTKYSPGWGSIKAYSKSPSDS 109 Query: 95 LETSLKRLQCPRVDLFYLHMP------DHSTPVEETLRACHQLHQEGKFVELGLSNYAAW 148 ++ +L +L VDLF +H P H +E+ A + + GK E+G+SN A Sbjct: 110 IDKALAQLGVDYVDLFLIHSPFFTTEQTHGYTLEQAWEALVEAKKAGKVREIGISNAAIP 169 Query: 149 EVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGK 208 + ++ S + P V Q ++ + + + G+ AF+PLA Sbjct: 170 HLEKLFAASPSPEYY-PVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA------- 221 Query: 209 YKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQ 253 P+ R N AE + K E L+ LQ Sbjct: 222 ----------PLARVETNALAETLKRLAEKYKKTEAQVLLRYTLQ 256 >4IJC-A nrPDB Length = 344 Score = 136 bits (341), Expect = 2e-32, Method: Composition-based stats. Identities = 48/234 (20%), Positives = 82/234 (35%), Gaps = 51/234 (21%) Query: 5 LSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLR 64 L+ LG + +A ++ G+ IDTA+ Y ++E +G Sbjct: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAY---ETEPFVGEAIKE 83 Query: 65 L----GGSDCRVKIDTKAIP-LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP---- 115 L + I TK P L+ D + L SLK L VDL H P Sbjct: 84 LLEDGSIKREDLFITTKVWPVLW------DEVDRSLNESLKALGLEYVDLLLQHWPLCFE 137 Query: 116 ----------DHSTPVE--------------ETLRACHQLH---QEGKFVELGLSNYAAW 148 TPV+ ET + +++ + + +G+SN++ Sbjct: 138 KIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIE 197 Query: 149 EVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 + + C+ + PTV Q + Q+E F + + A++PL Sbjct: 198 YLERLIKECR----VKPTVNQVETHPHLPQMELRKFCFMHD--ILLTAYSPLGS 245 >1A80-A nrPDB Length = 277 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 66/318 (20%), Positives = 105/318 (33%), Gaps = 63/318 (19%) Query: 2 SRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGL 61 S L+ LG ++ + LE G+ IDTA +Y +E +G Sbjct: 4 SIVLNDGNSIPQLGYGVF--KVPPADTQRAVEEALEVGYRHIDTAAIYG---NEEGVGAA 58 Query: 62 GLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP- 120 G + + I TK L+ + D + SL +L +VDL+ +H P + Sbjct: 59 IAASGIARDDLFITTK---LWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADN 115 Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180 +L G +G+SN+ + I + ++P V Q + +Q E Sbjct: 116 YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIV----AATGVVPAVNQIELHPAYQQRE 171 Query: 181 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH 240 ++ ++ PL G KY D G +PV Sbjct: 172 IT--DWAAAHDVKIESWGPLGQG----KY---DLFGAEPVT------------------- 203 Query: 241 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 300 AA A + A LRW G V E+LE+NL Sbjct: 204 -------------AAAAAHGKTPAQAVLRWHLQ-------KGFVVFPKSVRRERLEENLD 243 Query: 301 A--AEEGPLEPAVVDAFN 316 + E A +DA + Sbjct: 244 VFDFDLTDTEIAAIDAMD 261 >1FRB-A nrPDB Length = 315 Score = 128 bits (322), Expect = 3e-30, Method: Composition-based stats. Identities = 36/215 (16%), Positives = 70/215 (32%), Gaps = 33/215 (15%) Query: 9 RPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGS 68 P LG + +A ++ G+ ID A+ Y G ++ Sbjct: 12 MPIVGLGTWKSPPNQ----VKEAVKAAIDAGYRHIDCAYAYCNENE----VGEAIQEKIK 63 Query: 69 DCRVKIDTKA--IPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE---- 122 + V+ + L+ + L+ + +L L+ +DL+ +H P P + Sbjct: 64 EKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFP 123 Query: 123 ---------------ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTV 167 E +L +G LG+SN+ +++ + K P Sbjct: 124 KDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLN--KPGLKHKPVT 181 Query: 168 YQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 Q + Q +L G+ A++PL Sbjct: 182 NQVECHPYLTQ--EKLIQYCHSKGISVTAYSPLGS 214 >1C9W-A nrPDB Length = 315 Score = 127 bits (320), Expect = 5e-30, Method: Composition-based stats. Identities = 39/221 (17%), Positives = 72/221 (32%), Gaps = 31/221 (14%) Query: 3 RQLSRARPATVLGAMEMGRRMDAPTS-AAVTRAFLERGHTEIDTAFVYSEGQSE-TILGG 60 +LS ++G +G P + ++ G+ ID A+ Y + Sbjct: 4 VELSTKAKMPIVG---LGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQE 60 Query: 61 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120 + I +K L+ + L+ + +L L+ +DL+ +H P P Sbjct: 61 KIKEKAVRREDLFIVSK---LWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQP 117 Query: 121 VEE-------------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161 +E +L EG LG+SN+ +++ I K Sbjct: 118 GKELFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILN--KPGL 175 Query: 162 WILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 P Q + Q +L G+ A++PL Sbjct: 176 KHKPVTNQVECHPYLTQ--EKLIEYCHSKGITVTAYSPLGS 214 >3O3R-A nrPDB Length = 316 Score = 127 bits (319), Expect = 6e-30, Method: Composition-based stats. Identities = 36/215 (16%), Positives = 74/215 (34%), Gaps = 33/215 (15%) Query: 9 RPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGS 68 P LG + +A ++ G+ D A+VY Q+E+ +G ++ Sbjct: 13 MPLVGLGTWKSPPGQ----VKEAVKAAIDAGYRHFDCAYVY---QNESEVGE-AIQEKIK 64 Query: 69 DCRVKIDTKA--IPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEE--- 123 + V+ + L+ + ++ + +L L+ +DL+ +H P +E Sbjct: 65 EKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGKEFLP 124 Query: 124 ----------------TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTV 167 +L +G LG+SN+ +++ + K P Sbjct: 125 KDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLN--KPGLKHKPVT 182 Query: 168 YQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAG 202 Q + Q +L G+ A++PL Sbjct: 183 NQVECHPYLTQ--EKLIQYCHSKGIAVIAYSPLGS 215 >3WG6-A nrPDB Length = 307 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 44/213 (20%), Positives = 74/213 (34%), Gaps = 21/213 (9%) Query: 4 QLSRA--RPATVLGA----MEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETI 57 +LS PA G + G L G ID A +Y + Sbjct: 12 KLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKE--- 68 Query: 58 LGGLGLRLGGSDCRVKIDTKAIP----LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLH 113 +G +G + V I K G K + L+ L+ L VDL+ +H Sbjct: 69 IGIALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIH 128 Query: 114 MP-----DHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVY 168 P H + E R + EG +G+SN+ + + ++ +N +P V Sbjct: 129 FPYISEKSHGFDLVEAWRYLERAKNEGLARNIGVSNFT---IENLKSILDANTDSIPVVN 185 Query: 169 QGMYNAITRQVETELFPCLRHFGLRFYAFNPLA 201 Q ++A + + + G+ A+ PL Sbjct: 186 QIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLG 218 >4EXA-A nrPDB Length = 292 Score = 71.7 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 47/216 (21%), Positives = 66/216 (30%), Gaps = 33/216 (15%) Query: 8 ARPATVLGAMEMGRRM-----------DAPTSAAVTRAFLERGHTEIDTAFVYSEGQSET 56 A LG ++ GR D +A + + G IDTA Y G+SE Sbjct: 41 AVSPLGLGTVKFGRDQGVKYPSGFTIPDDREAADLLALARDLGINLIDTAPAY--GRSEE 98 Query: 57 ILGGLGLRLGGSDCRVKIDTKAIPLFGN-----SLKPDSLRFQLETSLKRLQCPRVDLFY 111 LG L L G I +K F + R +E SLKRL+ R++L Sbjct: 99 RLGPL---LRGQREHWVIVSKVGEEFVDGQSVFDFSAAHTRRSVERSLKRLETDRIELVL 155 Query: 112 LHMPDHSTPV---EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVY 168 +H + + E L +EG GLS Sbjct: 156 VHSDGNDLDILENSEVYPTLAALKREGLIGAYGLSGKTVEGGLRALREGD--------CA 207 Query: 169 QGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGL 204 YN + + E + LA G Sbjct: 208 MVTYN-LNERAERPVIEYAAAHAKGILVKKALASGH 242 >5J7Z-A nrPDB Length = 500 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 30/103 (29%), Gaps = 4/103 (3%) Query: 124 TLRACHQL---HQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180 T R H L HQ+G G + + W + + N NA +V Sbjct: 128 TARGMHVLLDNHQDGLSKAWGGNGFPEWAIESRPREWEPNPGFPLYYLMPSLNAGWDEVW 187 Query: 181 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRF 223 L H G A G G E N P RF Sbjct: 188 GNTHGALDHLGTALGALAERVEGK-PGVMGIELLNEPWPGSRF 229 >3NAF-A nrPDB Length = 798 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 21/65 (32%), Gaps = 8/65 (12%) Query: 150 VAEICTLCKSNGWILPTVYQGMYN--------AITRQVETELFPCLRHFGLRFYAFNPLA 201 + + ++ + I Y+ E + CL L F A + LA Sbjct: 152 IMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLA 211 Query: 202 GGLLT 206 GL T Sbjct: 212 QGLST 216 >3MT5-A nrPDB Length = 726 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 21/65 (32%), Gaps = 8/65 (12%) Query: 150 VAEICTLCKSNGWILPTVYQGMYN--------AITRQVETELFPCLRHFGLRFYAFNPLA 201 + + ++ + I Y+ E + CL L F A + LA Sbjct: 102 IMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLA 161 Query: 202 GGLLT 206 GL T Sbjct: 162 QGLST 166 >3BER-A nrPDB Length = 249 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 31/78 (39%), Gaps = 10/78 (12%) Query: 101 RLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSN 160 L +L++ M +H +P E + + + F +LG+++ +C C Sbjct: 12 DLGTE--NLYFQSMEEHDSPTEASQPIVEE-EETKTFKDLGVTDV-------LCEACDQL 61 Query: 161 GWILPTVYQGMYNAITRQ 178 GW PT Q + Q Sbjct: 62 GWTKPTKIQIEAIPLALQ 79 >3UWC-A nrPDB Length = 374 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 28/86 (32%), Gaps = 5/86 (5%) Query: 165 PTVYQGMYNAITRQV-----ETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQP 219 P +G+Y+ V +LF L+ G+ P+A L + G P Sbjct: 275 PVRREGVYHVFHIYVLRVKYRDQLFQYLKDNGIEVKIHYPIAMHLQPAAKSLGYQQGDFP 334 Query: 220 VGRFFGNTWAEMYRNRYWKEHHFEGI 245 + G + + Y E I Sbjct: 335 MAEKHGEAVITLPAHPYLTEEEINYI 360 >3U6N-A nrPDB Length = 696 Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 21/158 (13%), Positives = 47/158 (29%), Gaps = 13/158 (8%) Query: 150 VAEICTLCKSNGWILPTVYQGMYN--------AITRQVETELFPCLRHFGLRFYAFNPLA 201 + + ++ + I Y+ E + CL F A + LA Sbjct: 102 IMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLA 161 Query: 202 GGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFE--GIALVEKALQAAYGAS 259 GL T + + + +TW + Y E + E A V + Sbjct: 162 QGLST---MLANLFSMRSYIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELC 218 Query: 260 APSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQ 297 + + Y Q + +++ + ++++ Sbjct: 219 YVKLKLLLIAIEYKSEQRESRSRKRILINPGNHVKMQE 256 >3Q3N-A nrPDB Length = 500 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 10/31 (32%), Gaps = 3/31 (9%) Query: 84 NSLKPDSLRFQLETSLKRLQCP---RVDLFY 111 + + Q E SL L DLF Sbjct: 291 KEFMYEWIIGQFERSLIDLGLDKPWYWDLFL 321 >5Z1N-A nrPDB Length = 168 Score = 28.2 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 22/63 (34%), Gaps = 2/63 (3%) Query: 30 AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89 A L G +D AF Y + L + + + + +T L +P Sbjct: 63 AKVDRALRDGFNHLDRAFRYYGVKKAADLVVILEKASTALKEAEQETVT--LLTPFFRPH 120 Query: 90 SLR 92 +++ Sbjct: 121 NIQ 123 >2XY2-A nrPDB Length = 189 Score = 28.2 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 41/112 (36%), Gaps = 14/112 (12%) Query: 172 YNAITRQVETELFPCLRHFGLR--FYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWA 229 YN ++ + ++ G+R +N A G Y+ + + K G T Sbjct: 36 YNPQGEKIISTQRVVVQKEGVRSRLTIYN--ANIEDAGIYRCQATDAK-------GQTQE 86 Query: 230 EMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSA---TLRWMYHHSQLQ 278 +++ F + ++ Q ++S+ + W+YH+ ++ Sbjct: 87 ATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVT 138 >2WIM-A nrPDB Length = 291 Score = 28.2 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 41/112 (36%), Gaps = 14/112 (12%) Query: 172 YNAITRQVETELFPCLRHFGLR--FYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWA 229 YN ++ + ++ G+R +N A G Y+ + + K G T Sbjct: 38 YNPQGEKIISTQRVVVQKEGVRSRLTIYN--ANIEDAGIYRCQATDAK-------GQTQE 88 Query: 230 EMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSA---TLRWMYHHSQLQ 278 +++ F + ++ Q ++S+ + W+YH+ ++ Sbjct: 89 ATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVT 140 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.124 0.334 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,295,083 Number of Sequences: 36641 Number of extensions: 454167 Number of successful extensions: 1452 Number of sequences better than 10.0: 64 Number of HSP's better than 10.0 without gapping: 85 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1144 Number of HSP's gapped (non-prelim): 120 length of query: 331 length of database: 10,336,785 effective HSP length: 97 effective length of query: 234 effective length of database: 6,782,608 effective search space: 1587130272 effective search space used: 1587130272 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.4 bits)