BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O95045 (317 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3P0E-A nrPDB 608 e-174 3KUK-A nrPDB 407 e-114 3EUF-A nrPDB 399 e-112 4TXN-A nrPDB 238 2e-63 5CYF-A nrPDB 219 9e-58 4R31-A nrPDB 66 2e-11 1U1E-A nrPDB 61 5e-10 4I2V-A nrPDB 58 6e-09 4R2W-A nrPDB 57 9e-09 3PNS-A nrPDB 51 8e-07 2ISC-A nrPDB 46 2e-05 3QPB-A nrPDB 41 6e-04 1ODL-A nrPDB 40 9e-04 4M3N-A nrPDB 40 0.002 4DAO-A nrPDB 40 0.002 4TYM-A nrPDB 38 0.007 3TL6-A nrPDB 37 0.014 1JE0-A nrPDB 37 0.017 1QOX-A nrPDB 36 0.017 3MB8-A nrPDB 36 0.025 3BJE-A nrPDB 36 0.025 1VHW-A nrPDB 35 0.044 1PR2-A nrPDB 35 0.058 4M7W-A nrPDB 34 0.100 3UAY-A nrPDB 34 0.10 3OCC-A nrPDB 33 0.13 1BGG-A nrPDB 33 0.14 4LDN-A nrPDB 32 0.29 6F5I-A nrPDB 32 0.39 4LKR-A nrPDB 31 0.60 4LNH-A nrPDB 30 0.95 1NW4-A nrPDB 30 1.9 5ZNI-A nrPDB 29 2.4 6B40-A nrPDB 28 4.5 3EMV-A nrPDB 28 6.2 5NGM-AT nrPDB 28 7.0 >3P0E-A nrPDB Length = 297 Score = 608 bits (1567), Expect = e-174, Method: Compositional matrix adjust. Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 21 GKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHK 80 GKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHK Sbjct: 4 GKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHK 63 Query: 81 ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV 140 ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV Sbjct: 64 ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV 123 Query: 141 TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS 200 TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS Sbjct: 124 TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS 183 Query: 201 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVF 260 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVF Sbjct: 184 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVF 243 Query: 261 AAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLG 314 AAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLG Sbjct: 244 AAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLG 297 >3KUK-A nrPDB Length = 309 Score = 407 bits (1047), Expect = e-114, Method: Compositional matrix adjust. Identities = 189/290 (65%), Positives = 231/290 (79%) Query: 24 FVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELG 83 V + NP++ M EDILYH L T TH+ PAMFGDVKFVCVGGSP+RMKAF ++ ELG Sbjct: 17 LVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVCVGGSPSRMKAFIKYVAMELG 76 Query: 84 FEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTII 143 F D +IC GTDRY M+K GPVL++SHGMG+PSI+IMLHELIKLL+HA C VT+I Sbjct: 77 FAHPGADYPNICEGTDRYAMFKVGPVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTLI 136 Query: 144 RIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEI 203 RIGTSGGIG+ PG+VVIT AVD FKP FEQ++L R+T+LD++L +EL CS E+ Sbjct: 137 RIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNTDLDEQLVQELARCSAEL 196 Query: 204 PNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAM 263 FPT+VG+TMCT DFYEGQGRLDGALCS++ + K DYL+ A+ AG+RNIEME++VFAAM Sbjct: 197 GEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAM 256 Query: 264 CGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 C CGL+AAVVCVTLL+RL+ DQI+ PHDVL EYQQRPQ L+ FI++RL Sbjct: 257 CNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVGQFIKKRL 306 >3EUF-A nrPDB Length = 328 Score = 399 bits (1025), Expect = e-112, Method: Compositional matrix adjust. Identities = 191/289 (66%), Positives = 231/289 (79%) Query: 25 VHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGF 84 V + NP + M EDILYH +L T HN PA+FGDVKFVCVGGSP+RMKAF + ELG Sbjct: 37 VRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGL 96 Query: 85 EEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIR 144 + D +ICAGTDRY MYK GPVL++SHGMGIPSISIMLHELIKLL++ARC +VTIIR Sbjct: 97 DCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIR 156 Query: 145 IGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP 204 IGTSGGIG+ PGTVVIT+ AVD+ FK FEQ++L V R T+L+K+L +EL CS E+ Sbjct: 157 IGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS 216 Query: 205 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 264 F T+VG+TMCT DFYEGQGRLDGALCS++ + K YL+ A+ AGVRNIEMES+VFAAMC Sbjct: 217 EFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMC 276 Query: 265 GLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 CGL+AAVVCVTLL+RL+ DQI+ P +VL EYQQRPQ L+S FI+++L Sbjct: 277 SACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 325 >4TXN-A nrPDB Length = 296 Score = 238 bits (608), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 126/291 (43%), Positives = 180/291 (61%), Gaps = 6/291 (2%) Query: 27 VKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEE 86 + N +L +DED+ +H TK+ + FGDVKFVCV GS R+ FA+ M K G Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 87 AEEDIKDICAGTD-RYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRI 145 E+I AG+ R+ +YK +L HGMGIPS IMLHE+ KLLH+A C DV IR+ Sbjct: 67 PVENI----AGSHARFVLYKVDHILFADHGMGIPSALIMLHEVTKLLHYAGCKDVLFIRL 122 Query: 146 GTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP- 204 GTSGG+G+ PGT+V++D V++ +P E IL V R T +D EL S+ + Sbjct: 123 GTSGGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTIVDLNTVNELKKLSENLSL 182 Query: 205 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 264 +VG T+ DFYE QGRLDG++C+FS+E+KL +L+ A++ G+RN+EME T + C Sbjct: 183 ECSVVVGGTIAANDFYEEQGRLDGSICTFSKEEKLAFLQSAYEHGIRNMEMEGTAITSHC 242 Query: 265 GLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGL 315 L G +A +VCVT ++RL+ DQI + D + QRP L+ +++R G+ Sbjct: 243 YLTGHRAILVCVTAVNRLEGDQITISTDEFTLFAQRPGQLVGEYLKRNNGI 293 >5CYF-A nrPDB Length = 296 Score = 219 bits (559), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 114/291 (39%), Positives = 176/291 (60%), Gaps = 6/291 (2%) Query: 27 VKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEE 86 + N +L +DED+ +H TK+ + FGDVKFVCV GS R+ FA+ M K G Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 87 AEEDIKDICAGTD-RYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRI 145 E+I AG+ R+ +YK +L HG+GIPS I++HE+ KLL++A C DV IR+ Sbjct: 67 PVENI----AGSHARFVLYKVDHILFADHGIGIPSTLILMHEVTKLLYYAGCKDVLFIRL 122 Query: 146 GTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP- 204 GTS G+G+ PGT+V++D V++ +P E IL V R T++D EL S+ + Sbjct: 123 GTSDGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTKVDSNAVNELKKLSENLSL 182 Query: 205 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 264 +VG T+ DFYE GRL+G++C+FS+E+KL +L+ + G+RN+EME + C Sbjct: 183 KCSVVVGGTITANDFYEELGRLNGSICTFSKEEKLAFLQSVYDHGIRNMEMEGAAITSHC 242 Query: 265 GLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGL 315 L G +A +VCVT+++RL+ D++ D ++Q P L+ +++R G+ Sbjct: 243 NLTGHRAILVCVTVVNRLETDEVTTSTDEFKLFEQLPGQLVGEYLKRNNGI 293 >4R31-A nrPDB Length = 279 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 84/296 (28%), Positives = 122/296 (41%), Gaps = 49/296 (16%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEA 87 +N Y M E ++HL L TK AM K + G P R + A M K + Sbjct: 16 ENLYFQSMSE--VFHLGL-TK-----AMLKGAKIAVIPGDPARSERIAQRMDKPEFLASS 67 Query: 88 EEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGT 147 E T + PV+ S G+G PS+SI + EL +L T +RIGT Sbjct: 68 REF-------TSWLGYLENEPVVVCSTGIGGPSVSICVEELAQLGVG------TFLRIGT 114 Query: 148 SGGIG--IAPGTVVITDIAV-----DSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS 200 +G I I G V++T AV F P + D T + L++ + Sbjct: 115 TGAIQPYINVGDVLVTTGAVRLDGASRHFAPLEYPAVADFSCTNA----------LYSAA 164 Query: 201 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDY---LKRAFKAGVRNIEMES 257 P VG T + FY GQ R D +FS + Y LK+ V N EMES Sbjct: 165 VAQGITP-YVGITASSDTFYPGQERYD----TFSGKVYPAYQGSLKQWQDLNVMNYEMES 219 Query: 258 TVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 MC GLKA +V +++R Q +P++ ++ ++ + + RRL Sbjct: 220 ATLFTMCAALGLKAGMVAGVIVNR---TQQEIPNEATIKSTEQKAVAVVIEAARRL 272 >1U1E-A nrPDB Length = 256 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 77/269 (28%), Positives = 106/269 (39%), Gaps = 53/269 (19%) Query: 61 FVCVGGSPNRMKAFALFM--------HKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAI 112 V G P+R++ A M H+E AE D K PV+ Sbjct: 24 LAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGK---------------PVIVC 68 Query: 113 SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITDIAV----- 165 S G+G PS SI + EL +L T +RIGT+G I I G V++T +V Sbjct: 69 STGIGGPSTSIAVEELAQLGIR------TFLRIGTTGAIQPHINVGDVLVTTASVRLDGA 122 Query: 166 DSFFKP-RFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQG 224 F P F V D E + L +K I T VG T + FY GQ Sbjct: 123 SLHFAPLEFPAVA-----------DFECTTALVEAAKSI-GATTHVGVTASSDTFYPGQE 170 Query: 225 RLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDC 284 R D R K ++ GV N EMES MC GL+A +V +++R Sbjct: 171 RYDTYSGRVVRHFK-GSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNR--- 226 Query: 285 DQINLPHDVLVEYQQRPQLLISNFIRRRL 313 Q +P+ ++ + + I RRL Sbjct: 227 TQQEIPNAETMKQTESHAVKIVVEAARRL 255 >4I2V-A nrPDB Length = 253 Score = 57.8 bits (138), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 70/247 (28%), Positives = 97/247 (39%), Gaps = 51/247 (20%) Query: 61 FVCVGGSPNRMKAFALFM--------HKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAI 112 V G P R++ A M H+E AE D K V+ Sbjct: 21 LAIVPGDPQRVEKIAKLMDNPVHLASHREFTSWRAELDGK---------------AVIVC 65 Query: 113 SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITDIAV----- 165 S G+G PS SI + EL +L T +RIGT+G I I G V++T AV Sbjct: 66 STGIGGPSTSIAVEELAQL------GVRTFLRIGTTGAIQPHINVGDVLVTTAAVRLDGA 119 Query: 166 DSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGR 225 F P + D T + L N +K + T +G T + FY GQ R Sbjct: 120 SLHFAPMEFPAVADFSCTTA----------LVNAAKSV-GATTHIGITASSDTFYPGQER 168 Query: 226 LDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCD 285 D R K ++ GV N EMES MC GL+A +V +++R Sbjct: 169 YDTFSGRVVRHFK-GSMEEWQSMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNR---T 224 Query: 286 QINLPHD 292 Q +P++ Sbjct: 225 QQEIPNE 231 >4R2W-A nrPDB Length = 252 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 99/251 (39%), Gaps = 42/251 (16%) Query: 40 LYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTD 99 ++HL L TK AM V G P R+K A M E Sbjct: 4 VFHLGL-TK-----AMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTS------- 50 Query: 100 RYCMYKTG-PVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPG 156 Y Y G PV+ S G+G PS SI + EL +L + T +R+GT+G I + G Sbjct: 51 -YLAYADGKPVVICSTGIGGPSTSIAVEELAQLGVN------TFLRVGTTGAIQPHVNVG 103 Query: 157 TVVITDIAV-----DSFFKP-RFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLV 210 V++T +V F P F V + E + + ++ P + Sbjct: 104 DVIVTQASVRLDGASLHFAPMEFPAV-----------ANFECTTAMVAACRDAGVEPH-I 151 Query: 211 GHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLK 270 G T + FY GQ R D +R + +K GV N EMES MC G + Sbjct: 152 GVTASSDTFYPGQERYDTVTGRVTR-RFAGSMKEWQDMGVLNYEMESATLFTMCATQGWR 210 Query: 271 AAVVCVTLLDR 281 AA V +++R Sbjct: 211 AACVAGVIVNR 221 >3PNS-A nrPDB Length = 261 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 68/266 (25%), Positives = 100/266 (37%), Gaps = 46/266 (17%) Query: 61 FVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKT----GPVLAISHGM 116 + G P R++ A M D A Y +Y+ V+ S G+ Sbjct: 28 LAIIPGDPARVQKIAELM-----------DNPVFLASHREYTVYRAELDGQSVVVCSTGI 76 Query: 117 GIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVIT------DIAVDSF 168 G PS SI + EL +L T +R+GT+G I + G +++T D A F Sbjct: 77 GGPSTSIAVEELAQLGVR------TFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHF 130 Query: 169 FKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDG 228 F V ++ T +E + +G T + FY GQ R D Sbjct: 131 APMEFPAVPDFDVATAMKAAAQESGATVH------------MGVTASSDTFYPGQERYDT 178 Query: 229 ALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQIN 288 R + +K GV N EMES MC GLKA V +++R Q Sbjct: 179 FTGRVVRRFQ-GSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRT---QKE 234 Query: 289 LP-HDVLVEYQQRPQLLISNFIRRRL 313 +P H L E + R ++ R+ L Sbjct: 235 IPDHATLKETEARSIKVVVEAARKML 260 >2ISC-A nrPDB Length = 239 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 31/177 (17%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGT---VVI 160 YK P+ + HGMG+PSI I EL ++ TIIR+GT G I + T V+ Sbjct: 52 YKGKPISVMGHGMGLPSICIYAEEL-----YSTYKVKTIIRVGTCGAIDMDIHTRDIVIF 106 Query: 161 TDIAVDS-FFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDF 219 T +S + RF +D+ + D + L + +KE+ N P VG T F Sbjct: 107 TSAGTNSKINRIRF----MDHDYPATASFDVVCA--LVDAAKEL-NIPAKVGKGFSTDLF 159 Query: 220 YEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCV 276 Y Q L + K +L +EMES + L G +A +C Sbjct: 160 YNPQTELAQLM------NKFHFLA---------VEMESAGLFPIADLYGARAGCICT 201 >3QPB-A nrPDB Length = 282 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 77/271 (28%), Positives = 108/271 (39%), Gaps = 44/271 (16%) Query: 41 YHLDLGTKTHNLPAMFGDV-KFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTD 99 Y ++G + H L GDV ++V + G P R A D + A + Sbjct: 27 YSGEVGLQYH-LQIRPGDVGRYVIMPGDPKRCAKIAEHF-----------DNAVLVADSR 74 Query: 100 RYCMYKTG-----PVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--G 152 Y Y TG V S G+G PS SI + EL KL C T IR+GT GGI Sbjct: 75 EYVTY-TGTLNGEKVSVTSTGIGGPSASIAMEEL-KL-----CGADTFIRVGTCGGIELD 127 Query: 153 IAPGTVVITDIAVDSFFKPRFEQVILDNI-VTRSTELDKELSEELFNCSKEIPNFPTLVG 211 + G +VI A+ R E + + D E++ L N +K++ + + G Sbjct: 128 VKGGDIVIATGAI------RMEGTSKEYAPIEFPAVADLEVTNALVNAAKKL-GYTSHAG 180 Query: 212 HTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMEST---VFAAMCGL-C 267 C FY GQ + S+ K + KR G + EMES V A+ G+ C Sbjct: 181 VVQCKDAFY-GQHEPERMPVSYELLNKWEAWKR---LGTKASEMESAALFVAASHLGVRC 236 Query: 268 GLKAAVVCVTLLDRLDCDQINLPHDVLVEYQ 298 G VV + L D + HD Q Sbjct: 237 GSDFLVVGNQERNALGMDN-PMAHDTEAAIQ 266 >1ODL-A nrPDB Length = 235 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 8/65 (12%) Query: 103 MYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVI 160 +YK PV + GMG PS +I++ EL++L AR ++R+GT+G +APG +++ Sbjct: 52 LYKGVPVSVQTTGMGTPSAAIVVEELVRL--GARV----LVRVGTAGAASSDLAPGELIV 105 Query: 161 TDIAV 165 AV Sbjct: 106 AQGAV 110 >4M3N-A nrPDB Length = 254 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/199 (23%), Positives = 77/199 (38%), Gaps = 44/199 (22%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG-------IAPG 156 YK V GMGIPS SI +HEL++ C T+IR+GT+G I + Sbjct: 74 YKGKRVSVQGTGMGIPSASIYIHELVQFY----GCK-TLIRVGTAGAITERLKLRDLVIA 128 Query: 157 TVVITDIAVDS--FFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTM 214 TD ++++ F + + +++ R+ E + P VG+ + Sbjct: 129 QAACTDSSINNLRFAGQNYAPIATFDLLRRAYE------------QAQSRGMPVHVGNVL 176 Query: 215 CTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVV 274 T FY Q F GV +EME+ + G++A + Sbjct: 177 STDTFYHDQPNPYQLWAQF---------------GVLAVEMEAAGLYTLAAKFGVQA--L 219 Query: 275 CV-TLLDRLDCDQINLPHD 292 C+ T+ D L + P + Sbjct: 220 CILTISDHLITGEKTTPQE 238 >4DAO-A nrPDB Length = 253 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 30/171 (17%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV-TIIRIGTSGGIGIAPGTVVITD 162 YK + GMG+PSISI ++ELI+ DV +IR+G+ G I V + D Sbjct: 72 YKGKKISVQGTGMGVPSISIYVNELIQ------SYDVQNLIRVGSCGAI---RKDVKVRD 122 Query: 163 I--AVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFY 220 + A+ S + +V + V + D EL + ++ +K+ P VG FY Sbjct: 123 VILAMTSSTDSQMNRVAFGS-VDFAPCADFELLKNAYDAAKD-KGVPVTVGSVFTADQFY 180 Query: 221 EGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKA 271 +++ + K GV +EME+T + G KA Sbjct: 181 NDDSQIE----------------KLAKYGVLGVEMETTALYTLAAKHGRKA 215 >4TYM-A nrPDB Length = 258 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 44/162 (27%), Positives = 67/162 (41%), Gaps = 41/162 (25%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG---------IA 154 YK V + GMG+PSISI ELI T+IR+GT+G I +A Sbjct: 74 YKGHRVSVMGTGMGMPSISIYARELI-----VDYGVKTLIRVGTAGAINPDIHVRELVLA 128 Query: 155 PGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTM 214 ++I + + + F Q+ D +L ++ ++ +KE+ + T VG + Sbjct: 129 QAAATNSNIIRNDWPEFDFPQI-----------ADFKLLDKAYHIAKEM-DITTHVGSVL 176 Query: 215 CTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEME 256 + FY Q + AL K GV IEME Sbjct: 177 SSDVFYSNQPDRNMALG---------------KLGVHAIEME 203 >3TL6-A nrPDB Length = 242 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 9/82 (10%) Query: 97 GTDRYCMYKTGPVLAI-SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GI 153 G Y Y G L++ +HGMG+PSI I +EL R IIRIG++G + Sbjct: 53 GAVGYTGYYKGVKLSVQAHGMGMPSIGIYAYELFNFYGVKR-----IIRIGSAGAFDESL 107 Query: 154 APGTVVITDIA-VDSFFKPRFE 174 G +VI A DS F+ +++ Sbjct: 108 KLGDIVIGMGACYDSNFERQYD 129 >1JE0-A nrPDB Length = 236 Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust. Identities = 49/176 (27%), Positives = 73/176 (41%), Gaps = 28/176 (15%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVIT 161 Y V +HG+G PSI+I+L EL L + IR GT+G + I G +I Sbjct: 52 YNGETVSIATHGIGGPSIAIVLEELAMLGAN------VFIRYGTTGALVPYINLGEYIIV 105 Query: 162 DIAVDSFFKPR-FEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFY 220 A S+ + F Q + DN ST D EL+ +L S N VG+ + FY Sbjct: 106 TGA--SYNQGGLFYQYLRDNACVASTP-DFELTNKLV-TSFSKRNLKYYVGNVFSSDAFY 161 Query: 221 EGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCV 276 + +++K+ G +EME + + G K+A V V Sbjct: 162 ---------------AEDEEFVKKWSSRGNIAVEMECATLFTLSKVKGWKSATVLV 202 >1QOX-A nrPDB Length = 449 Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust. Identities = 39/122 (31%), Positives = 52/122 (42%), Gaps = 21/122 (17%) Query: 40 LYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTD 99 LYH DL P D GG +R+ A + EL F+E IK + Sbjct: 118 LYHWDL-------PQALQDQ-----GGWGSRITIDAFAEYAELMFKELGGKIKQWITFNE 165 Query: 100 RYCMYKTGPVLAISHGMGIPSISIML---HELIKLLHHARCCDVTIIR-IGTSGGIGIAP 155 +CM L + H G + + + H L L+ H R VT+ R +G SG IGIAP Sbjct: 166 PWCMAFLSNYLGV-HAPGNKDLQLAIDVSHHL--LVAHGRA--VTLFRELGISGEIGIAP 220 Query: 156 GT 157 T Sbjct: 221 NT 222 >3MB8-A nrPDB Length = 279 Score = 35.8 bits (81), Expect = 0.025, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 103 MYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG---IAPGTVV 159 +Y + P+ ISHG+G P SI + EL L IIR GT G + + G V Sbjct: 58 VYDSQPITVISHGIGCPGTSIAIEELAYLGAK------VIIRAGTCGSLKPKTLKQGDVC 111 Query: 160 ITDIAVD 166 +T AV+ Sbjct: 112 VTYAAVN 118 >3BJE-A nrPDB Length = 349 Score = 35.8 bits (81), Expect = 0.025, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 104/276 (37%), Gaps = 64/276 (23%) Query: 66 GSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIML 125 G P R+ + + K+ A D ++I T YK PV IS GMG+ +I I+L Sbjct: 50 GDPGRVDVISGYFDKD--SIRASRDHREIRFATG---TYKGTPVTVISTGMGVDNIEIVL 104 Query: 126 HELIKL----------LHHARCCD------------VTIIRIGTSGGIG--IAPGTVVIT 161 +E+ L H D + IIR+GT G + P + +T Sbjct: 105 NEIHALKEYDMERGQWRHRKGDADAPSAGPFFDPSTMKIIRLGTCGSPAESVPPLALAVT 164 Query: 162 DIAVD----SFF------KPRFEQVILDNIVTRSTEL---DKELSEELFNCSKEI----- 203 A+ S + + +Q + IV T L D S N +K I Sbjct: 165 RHAIGMDNTSLYYSAGTRETSKDQQEIRRIVREQTGLRAIDIYTSMAHPNITKSICAACD 224 Query: 204 -PNFPT---------LVGHTMCTYDFYEGQGRLDGA----LCSFSREKKLDYLKRAFKAG 249 N T ++G T FY QGR G L + ++L LK G Sbjct: 225 AHNAATGSEADKQQYVIGTTATASGFYGCQGRRVGRFMKHLTVPNMVEELGSLKFNLSNG 284 Query: 250 VR---NIEMESTVFAAMCGLCGLKAAVVCVTLLDRL 282 V NIEME++ + + G +A CV + R+ Sbjct: 285 VEVVTNIEMETSAICYLSDMLGYQAGAACVVVSKRV 320 >1VHW-A nrPDB Length = 253 Score = 35.0 bits (79), Expect = 0.044, Method: Compositional matrix adjust. Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 7/59 (11%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVI 160 YK + + HGMGIPS SI + ELIK + IIR+G+ G + GI VVI Sbjct: 55 YKGRRISVMGHGMGIPSCSIYVTELIKDYGVKK-----IIRVGSCGAVNEGIKVRDVVI 108 >1PR2-A nrPDB Length = 239 Score = 34.7 bits (78), Expect = 0.058, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 12/104 (11%) Query: 49 THNLPAMFGD-VKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTG 107 T ++ A GD V + G P R K A E E+A E + ++ YK Sbjct: 3 TPHINAEMGDFADVVLMPGDPLRAKYIA-----ETFLEDARE-VNNVRGMLGFTGTYKGR 56 Query: 108 PVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI 151 + + HGMGIPS SI ELI + IIR+G+ G + Sbjct: 57 KISVMGHGMGIPSCSIYTKELITDFGVKK-----IIRVGSCGAV 95 >4M7W-A nrPDB Length = 258 Score = 33.9 bits (76), Expect = 0.100, Method: Compositional matrix adjust. Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 17/120 (14%) Query: 32 LDLMDEDILYHLDLGTKTHNLPAMFGDV-KFVCVGGSPNRMKAFA-LFMHKELGFEEAEE 89 +DL E+ LY +GT ++ A GDV + + + G P R K A F+ + + Sbjct: 11 VDLGTEN-LYFQSMGTP--HIGANRGDVAETILLPGDPLRAKYIAETFLEDVVQYN---- 63 Query: 90 DIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSG 149 +++ + T YK V GMG+PSI I HELI +IR+GT+G Sbjct: 64 NVRGMLGFT---GTYKGKKVSVQGTGMGVPSIGIYSHELITEFGVKN-----LIRVGTAG 115 >3UAY-A nrPDB Length = 235 Score = 33.9 bits (76), Expect = 0.10, Method: Compositional matrix adjust. Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 37/175 (21%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVI- 160 YK V GMG+PSISI ++ELI+ +IR+GT G I + V+I Sbjct: 52 YKGKRVSVQGTGMGVPSISIYVNELIQSYGVKN-----LIRVGTCGAIQKDVKVRDVIIA 106 Query: 161 ----TDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCT 216 TD ++ P F+ N +L ++ ++ E VG+ + Sbjct: 107 MTACTDSNMNRLTFPGFDFAPAANF---------DLLKKAYDAGTE-KGLHVRVGNVLTA 156 Query: 217 YDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKA 271 FY + +D +K+ GV +EME+T + G+ A Sbjct: 157 DVFY---------------RESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNA 196 >3OCC-A nrPDB Length = 239 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI 151 YK + + HGMGIPS SI ELI + IIR+G+ G + Sbjct: 53 YKGRKISVMGHGMGIPSCSIYAKELITDFGVKK-----IIRVGSCGAV 95 >1BGG-A nrPDB Length = 448 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 45/120 (37%), Gaps = 21/120 (17%) Query: 40 LYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTD 99 LYH DL P D GG NR A E F E I+ + Sbjct: 119 LYHWDL-------PQALQDA-----GGWGNRRTIQAFVQFAETMFREFHGKIQHWLTFNE 166 Query: 100 RYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIR----IGTSGGIGIAP 155 +C+ +L + H G+ + L I + HH +R +GTSG IGIAP Sbjct: 167 PWCIAFLSNMLGV-HAPGLTN----LQTAIDVGHHLLVAHGLSVRRFRELGTSGQIGIAP 221 >4LDN-A nrPDB Length = 261 Score = 32.3 bits (72), Expect = 0.29, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 27/127 (21%) Query: 32 LDLMDEDILYHLDLGTKTHNLPA-MFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEED 90 +DL E+ LY + T N P F D + + G P R K A E Sbjct: 11 VDLGTEN-LYFQSMSTPHINAPLDAFADT--ILMPGDPLRAKLIA------------ETY 55 Query: 91 IKDICAGTDRYCM------YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIR 144 ++++ TD M +K + + HGMG PS SI HEL+ IR Sbjct: 56 LENVVQVTDVRGMLGFTGEFKGRKISVMGHGMGAPSASIYFHELMTTYKVKN-----FIR 110 Query: 145 IGTSGGI 151 IG+ G I Sbjct: 111 IGSCGAI 117 >6F5I-A nrPDB Length = 233 Score = 32.0 bits (71), Expect = 0.39, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPG---TVVI 160 YK + + HGMGI S +I + ELIK ++RIGT G I G ++ Sbjct: 52 YKGRGISLMGHGMGIASCTIYVTELIKTYQVKE-----LLRIGTCGAISPKVGLKDIIMA 106 Query: 161 TDIAVDS 167 T + DS Sbjct: 107 TGASTDS 113 >4LKR-A nrPDB Length = 256 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 20/121 (16%) Query: 32 LDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEE-- 89 +DL E+ LY + + P F + V + G P R K A E +A E Sbjct: 11 VDLGTEN-LYFQSMTAHINAQPTDFAET--VIMPGDPLRAKYIA-----ETYLTDAVEVT 62 Query: 90 DIKDICAGTDRYCMYKTGPVLAI-SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTS 148 +++++ Y Y G +++ HGMGI S+ + HELI R IIRIG+ Sbjct: 63 NVRNMLG----YTGYYQGQRISVMGHGMGISSMVLYGHELINFFGVKR-----IIRIGSL 113 Query: 149 G 149 G Sbjct: 114 G 114 >4LNH-A nrPDB Length = 266 Score = 30.4 bits (67), Expect = 0.95, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 17/108 (15%) Query: 61 FVCVGGSPNRMKAFALFMHK-ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIP 119 +V V G P+R+ M EL E E + + +YK + S G+G P Sbjct: 39 YVIVCGEPDRVNRIVELMDNVELLAENREYRVFN--------GVYKGTTITICSTGIGAP 90 Query: 120 SISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITDIAV 165 S+ I + EL KL C +IR+G++G + I G +++ + AV Sbjct: 91 SMIIAVEEL-KL-----CGATHVIRVGSAGAMQDHIQLGELIVAEGAV 132 >1NW4-A nrPDB Length = 276 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 51/223 (22%), Positives = 84/223 (37%), Gaps = 45/223 (20%) Query: 102 CMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG---IAPGTV 158 C YK L +SHG+G ++ EL + + A+ IIR G+ G + I G + Sbjct: 54 CHYKGQKFLCVSHGVGSAGCAVCFEELCQ--NGAK----VIIRAGSCGSLQPDLIKRGDI 107 Query: 159 VITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYD 218 I + AV + R +++ + D + + L C++E+ N P G ++ + D Sbjct: 108 CICNAAVR---EDRVSHLLIHGDFPAVGDFD--VYDTLNKCAQEL-NVPVFNGISVSS-D 160 Query: 219 FYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVV---- 274 Y + L +S KA +EME + L +K + Sbjct: 161 MYYPNKIIPSRLEDYS------------KANAAVVEMELATLMVIGTLRKVKTGGILIVD 208 Query: 275 -CVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLC 316 C D D D +PH + N I+ LG C Sbjct: 209 GCPFKWDEGDFDNNLVPHQ------------LENMIKIALGAC 239 >5ZNI-A nrPDB Length = 245 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 15/125 (12%) Query: 102 CMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG---IAPGTV 158 C YK L +SHG+G ++ EL + + A+ IIR G+ G + I G + Sbjct: 52 CHYKGQKFLCVSHGVGSAGCAVCFEELCQ--NGAK----VIIRAGSCGSLQPDLIKRGDI 105 Query: 159 VITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYD 218 I + AV + R +++ + D + + L C++E+ N P G ++ + Sbjct: 106 CICNAAVR---EDRVSHLLIHGDFPAVGDFD--VYDTLNKCAQEL-NVPVFNGISVSSDM 159 Query: 219 FYEGQ 223 +Y + Sbjct: 160 YYPNK 164 >6B40-A nrPDB Length = 658 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 24/38 (63%), Gaps = 4/38 (10%) Query: 190 KELSEELFNCSKEI---PNFPTLVGHTMCTYDFYEGQG 224 +EL +E+ N K++ PN PTLV HT+C D +G G Sbjct: 201 EELEDEIVNGLKKLGRDPNDPTLVIHTICK-DGADGMG 237 >3EMV-A nrPDB Length = 253 Score = 27.7 bits (60), Expect = 6.2, Method: Compositional matrix adjust. Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 25/119 (21%) Query: 35 MDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALF--MHKELGFEEAEEDIK 92 M+ ++ H+ L TK P V V G P R+ + + +L + + ++ Sbjct: 1 MEGEMQRHIKL-TKAQTTPV-------VLVVGDPGRVDKVKVLCDSYVDLAYNREYKSVE 52 Query: 93 DICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI 151 C YK L +SHG+G +I EL+ + A+ IIR G+ G + Sbjct: 53 ---------CTYKGQKFLCVSHGVGSAGCAICFEELMN--NGAK----VIIRAGSCGSL 96 >5NGM-AT nrPDB Length = 217 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Query: 98 TDRYCMYKTGPVLAISHGMGIPSISIMLHEL--IKLLHHARCCDVTIIRIGTSGGIGIAP 155 +D + K+G V A+ +G G ++S+ + E+ IK++ +G +G I + Sbjct: 16 SDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIRE----------VGRNGVIELGV 65 Query: 156 GTVVITDIAVDSFFKPRFEQV 176 G+ I + D F P Q+ Sbjct: 66 GSKTIKVMVADYQFDPLKNQI 86 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3P0E-A nrPDB 413 e-116 3KUK-A nrPDB 389 e-109 3EUF-A nrPDB 380 e-106 4TXN-A nrPDB 355 2e-98 5CYF-A nrPDB 346 6e-96 4R31-A nrPDB 247 4e-66 1U1E-A nrPDB 244 3e-65 4I2V-A nrPDB 238 3e-63 4R2W-A nrPDB 235 2e-62 3PNS-A nrPDB 228 2e-60 3QPB-A nrPDB 187 5e-48 4M3N-A nrPDB 158 2e-39 2ISC-A nrPDB 150 7e-37 4DAO-A nrPDB 141 4e-34 1ODL-A nrPDB 115 3e-26 Sequences not found previously or not previously below threshold: 3UAY-A nrPDB 127 5e-30 3OCC-A nrPDB 119 2e-27 1PR2-A nrPDB 118 4e-27 1VHW-A nrPDB 113 1e-25 4M7W-A nrPDB 113 1e-25 4LDN-A nrPDB 107 6e-24 1JE0-A nrPDB 104 3e-23 4TYM-A nrPDB 101 4e-22 6F5I-A nrPDB 101 6e-22 3TL6-A nrPDB 100 2e-21 4LNH-A nrPDB 98 7e-21 4LKR-A nrPDB 92 2e-19 3MB8-A nrPDB 79 2e-15 3EMV-A nrPDB 78 4e-15 5ZNI-A nrPDB 74 8e-14 1NW4-A nrPDB 74 8e-14 3BJE-A nrPDB 69 3e-12 4KN5-A nrPDB 44 7e-05 6IF8-A nrPDB 42 3e-04 4L0M-A nrPDB 40 0.001 1ZOS-A nrPDB 40 0.002 4G41-A nrPDB 39 0.003 4WKO-A nrPDB 35 0.052 3EEI-A nrPDB 32 0.37 3C8E-A nrPDB 31 0.57 3HQ9-A nrPDB 31 0.65 1TQY-B nrPDB 30 1.1 3K4W-A nrPDB 29 1.8 3LGS-A nrPDB 29 2.2 5DK6-A nrPDB 29 2.6 2RC9-A nrPDB 28 4.0 2QSZ-A nrPDB 28 4.1 3MJO-A nrPDB 28 5.8 3DHZ-A nrPDB 28 5.8 >3P0E-A nrPDB Length = 297 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 21 GKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHK 80 GKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHK Sbjct: 4 GKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHK 63 Query: 81 ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV 140 ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV Sbjct: 64 ELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV 123 Query: 141 TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS 200 TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS Sbjct: 124 TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCS 183 Query: 201 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVF 260 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVF Sbjct: 184 KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVF 243 Query: 261 AAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLG 314 AAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLG Sbjct: 244 AAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLG 297 >3KUK-A nrPDB Length = 309 Score = 389 bits (999), Expect = e-109, Method: Composition-based stats. Identities = 189/290 (65%), Positives = 231/290 (79%) Query: 24 FVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELG 83 V + NP++ M EDILYH L T TH+ PAMFGDVKFVCVGGSP+RMKAF ++ ELG Sbjct: 17 LVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVCVGGSPSRMKAFIKYVAMELG 76 Query: 84 FEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTII 143 F D +IC GTDRY M+K GPVL++SHGMG+PSI+IMLHELIKLL+HA C VT+I Sbjct: 77 FAHPGADYPNICEGTDRYAMFKVGPVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTLI 136 Query: 144 RIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEI 203 RIGTSGGIG+ PG+VVIT AVD FKP FEQ++L R+T+LD++L +EL CS E+ Sbjct: 137 RIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNTDLDEQLVQELARCSAEL 196 Query: 204 PNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAM 263 FPT+VG+TMCT DFYEGQGRLDGALCS++ + K DYL+ A+ AG+RNIEME++VFAAM Sbjct: 197 GEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAM 256 Query: 264 CGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 C CGL+AAVVCVTLL+RL+ DQI+ PHDVL EYQQRPQ L+ FI++RL Sbjct: 257 CNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVGQFIKKRL 306 >3EUF-A nrPDB Length = 328 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 191/289 (66%), Positives = 231/289 (79%) Query: 25 VHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGF 84 V + NP + M EDILYH +L T HN PA+FGDVKFVCVGGSP+RMKAF + ELG Sbjct: 37 VRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGL 96 Query: 85 EEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIR 144 + D +ICAGTDRY MYK GPVL++SHGMGIPSISIMLHELIKLL++ARC +VTIIR Sbjct: 97 DCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIR 156 Query: 145 IGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP 204 IGTSGGIG+ PGTVVIT+ AVD+ FK FEQ++L V R T+L+K+L +EL CS E+ Sbjct: 157 IGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS 216 Query: 205 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 264 F T+VG+TMCT DFYEGQGRLDGALCS++ + K YL+ A+ AGVRNIEMES+VFAAMC Sbjct: 217 EFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMC 276 Query: 265 GLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 CGL+AAVVCVTLL+RL+ DQI+ P +VL EYQQRPQ L+S FI+++L Sbjct: 277 SACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 325 >4TXN-A nrPDB Length = 296 Score = 355 bits (910), Expect = 2e-98, Method: Composition-based stats. Identities = 124/290 (42%), Positives = 177/290 (61%), Gaps = 4/290 (1%) Query: 27 VKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEE 86 + N +L +DED+ +H TK+ + FGDVKFVCV GS R+ FA+ M K G Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 87 AEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIG 146 E+I R+ +YK +L HGMGIPS IMLHE+ KLLH+A C DV IR+G Sbjct: 67 PVENIA---GSHARFVLYKVDHILFADHGMGIPSALIMLHEVTKLLHYAGCKDVLFIRLG 123 Query: 147 TSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP-N 205 TSGG+G+ PGT+V++D V++ +P E IL V R T +D EL S+ + Sbjct: 124 TSGGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTIVDLNTVNELKKLSENLSLE 183 Query: 206 FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCG 265 +VG T+ DFYE QGRLDG++C+FS+E+KL +L+ A++ G+RN+EME T + C Sbjct: 184 CSVVVGGTIAANDFYEEQGRLDGSICTFSKEEKLAFLQSAYEHGIRNMEMEGTAITSHCY 243 Query: 266 LCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGL 315 L G +A +VCVT ++RL+ DQI + D + QRP L+ +++R G+ Sbjct: 244 LTGHRAILVCVTAVNRLEGDQITISTDEFTLFAQRPGQLVGEYLKRNNGI 293 >5CYF-A nrPDB Length = 296 Score = 346 bits (888), Expect = 6e-96, Method: Composition-based stats. Identities = 112/290 (38%), Positives = 173/290 (59%), Gaps = 4/290 (1%) Query: 27 VKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEE 86 + N +L +DED+ +H TK+ + FGDVKFVCV GS R+ FA+ M K G Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 87 AEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIG 146 E+I R+ +YK +L HG+GIPS I++HE+ KLL++A C DV IR+G Sbjct: 67 PVENIA---GSHARFVLYKVDHILFADHGIGIPSTLILMHEVTKLLYYAGCKDVLFIRLG 123 Query: 147 TSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP-N 205 TS G+G+ PGT+V++D V++ +P E IL V R T++D EL S+ + Sbjct: 124 TSDGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTKVDSNAVNELKKLSENLSLK 183 Query: 206 FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCG 265 +VG T+ DFYE GRL+G++C+FS+E+KL +L+ + G+RN+EME + C Sbjct: 184 CSVVVGGTITANDFYEELGRLNGSICTFSKEEKLAFLQSVYDHGIRNMEMEGAAITSHCN 243 Query: 266 LCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGL 315 L G +A +VCVT+++RL+ D++ D ++Q P L+ +++R G+ Sbjct: 244 LTGHRAILVCVTVVNRLETDEVTTSTDEFKLFEQLPGQLVGEYLKRNNGI 293 >4R31-A nrPDB Length = 279 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 77/288 (26%), Positives = 113/288 (39%), Gaps = 33/288 (11%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEA 87 +N Y M E ++HL L AM K + G P R + A M K + Sbjct: 16 ENLYFQSMSE--VFHLGLT------KAMLKGAKIAVIPGDPARSERIAQRMDKPEFLASS 67 Query: 88 EEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGT 147 E T + PV+ S G+G PS+SI + EL +L T +RIGT Sbjct: 68 REF-------TSWLGYLENEPVVVCSTGIGGPSVSICVEELAQLGVG------TFLRIGT 114 Query: 148 SGGIG--IAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPN 205 +G I I G V++T AV R + D + L++ + Sbjct: 115 TGAIQPYINVGDVLVTTGAVRLDGASRHFA-----PLEYPAVADFSCTNALYSAAVAQGI 169 Query: 206 FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCG 265 P VG T + FY GQ R D LK+ V N EMES MC Sbjct: 170 TP-YVGITASSDTFYPGQERYDTFSGKVYPA-YQGSLKQWQDLNVMNYEMESATLFTMCA 227 Query: 266 LCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 GLKA +V +++R Q +P++ ++ ++ + + RRL Sbjct: 228 ALGLKAGMVAGVIVNR---TQQEIPNEATIKSTEQKAVAVVIEAARRL 272 >1U1E-A nrPDB Length = 256 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 74/283 (26%), Positives = 107/283 (37%), Gaps = 31/283 (10%) Query: 33 DLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIK 92 M + ++HL L V G P+R++ A M K + E Sbjct: 2 SHMSKSDVFHLGLT------KNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREF-- 53 Query: 93 DICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG 152 T PV+ S G+G PS SI + EL +L T +RIGT+G I Sbjct: 54 -----TTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIR------TFLRIGTTGAIQ 102 Query: 153 --IAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLV 210 I G V++T +V + D E + L +K I T V Sbjct: 103 PHINVGDVLVTTASVRLDGASLHFA-----PLEFPAVADFECTTALVEAAKSI-GATTHV 156 Query: 211 GHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLK 270 G T + FY GQ R D R K ++ GV N EMES MC GL+ Sbjct: 157 GVTASSDTFYPGQERYDTYSGRVVRHFK-GSMEEWQAMGVMNYEMESATLLTMCASQGLR 215 Query: 271 AAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 A +V +++R Q +P+ ++ + + I RRL Sbjct: 216 AGMVAGVIVNR---TQQEIPNAETMKQTESHAVKIVVEAARRL 255 >4I2V-A nrPDB Length = 253 Score = 238 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 70/281 (24%), Positives = 104/281 (37%), Gaps = 31/281 (11%) Query: 35 MDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDI 94 M + ++HL L V G P R++ A M + E Sbjct: 1 MAKSDVFHLGLT------KNDLQGATLAIVPGDPQRVEKIAKLMDNPVHLASHREF---- 50 Query: 95 CAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG-- 152 T V+ S G+G PS SI + EL +L T +RIGT+G I Sbjct: 51 ---TSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGVR------TFLRIGTTGAIQPH 101 Query: 153 IAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGH 212 I G V++T AV + D + L N +K + T +G Sbjct: 102 INVGDVLVTTAAVRLDGASLHFA-----PMEFPAVADFSCTTALVNAAKSV-GATTHIGI 155 Query: 213 TMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAA 272 T + FY GQ R D R K ++ GV N EMES MC GL+A Sbjct: 156 TASSDTFYPGQERYDTFSGRVVRHFK-GSMEEWQSMGVMNYEMESATLLTMCASQGLRAG 214 Query: 273 VVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 +V +++R Q +P++ ++ + + I R L Sbjct: 215 MVAGVIVNR---TQQEIPNEETMKATESHAVKIVVEAARHL 252 >4R2W-A nrPDB Length = 252 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 66/276 (23%), Positives = 103/276 (37%), Gaps = 31/276 (11%) Query: 40 LYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTD 99 ++HL L AM V G P R+K A M E T Sbjct: 4 VFHLGLT------KAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREY-------TS 50 Query: 100 RYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGT 157 PV+ S G+G PS SI + EL +L + T +R+GT+G I + G Sbjct: 51 YLAYADGKPVVICSTGIGGPSTSIAVEELAQLGVN------TFLRVGTTGAIQPHVNVGD 104 Query: 158 VVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTY 217 V++T +V + + E + + ++ P +G T + Sbjct: 105 VIVTQASVRLDGASLHFA-----PMEFPAVANFECTTAMVAACRDAGVEP-HIGVTASSD 158 Query: 218 DFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVT 277 FY GQ R D +R +K GV N EMES MC G +AA V Sbjct: 159 TFYPGQERYDTVTGRVTRRF-AGSMKEWQDMGVLNYEMESATLFTMCATQGWRAACVAGV 217 Query: 278 LLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 313 +++R Q +P + ++ + + I ++L Sbjct: 218 IVNR---TQQEIPDEATMKKTEVSAVSIVVAAAKKL 250 >3PNS-A nrPDB Length = 261 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 69/286 (24%), Positives = 105/286 (36%), Gaps = 50/286 (17%) Query: 40 LYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTD 99 ++HL + A + G P R++ A M D A Sbjct: 13 VFHLGVT------EADLNGATLAIIPGDPARVQKIAELM-----------DNPVFLASHR 55 Query: 100 RYCMYK----TGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--I 153 Y +Y+ V+ S G+G PS SI + EL +L T +R+GT+G I + Sbjct: 56 EYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVR------TFLRVGTTGAIQPHV 109 Query: 154 APGTVVITDIAV-----DSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPT 208 G +++T +V F P + D V + + + Sbjct: 110 NVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATA-----------MKAAAQESGATV 158 Query: 209 LVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCG 268 +G T + FY GQ R D R + +K GV N EMES MC G Sbjct: 159 HMGVTASSDTFYPGQERYDTFTGRVVRRFQ-GSMKEWQDMGVLNFEMESATLLTMCASSG 217 Query: 269 LKAAVVCVTLLDRLDCDQINLP-HDVLVEYQQRPQLLISNFIRRRL 313 LKA V +++R Q +P H L E + R ++ R+ L Sbjct: 218 LKAGCVAGVIINR---TQKEIPDHATLKETEARSIKVVVEAARKML 260 >3QPB-A nrPDB Length = 282 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 72/283 (25%), Positives = 104/283 (36%), Gaps = 44/283 (15%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDV-KFVCVGGSPNRMKAFALFMHKELGFEE 86 +N Y ++ Y ++G + H L GDV ++V + G P R A Sbjct: 16 ENLYFQGHMQN--YSGEVGLQYH-LQIRPGDVGRYVIMPGDPKRCAKIAEHF-------- 64 Query: 87 AEEDIKDICAGTDRYCMY----KTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTI 142 D + A + Y Y V S G+G PS SI + EL C T Sbjct: 65 ---DNAVLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEEL------KLCGADTF 115 Query: 143 IRIGTSGGIGIAP--GTVVITDIAVDSFFKPRFEQVILDN-IVTRSTELDKELSEELFNC 199 IR+GT GGI + G +VI A+ R E + + D E++ L N Sbjct: 116 IRVGTCGGIELDVKGGDIVIATGAI------RMEGTSKEYAPIEFPAVADLEVTNALVNA 169 Query: 200 SKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTV 259 +K++ + + G C FY GQ + S+ K + KR G + EMES Sbjct: 170 AKKL-GYTSHAGVVQCKDAFY-GQHEPERMPVSYELLNKWEAWKR---LGTKASEMESAA 224 Query: 260 FAAMCG----LCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQ 298 CG VV + L D + HD Q Sbjct: 225 LFVAASHLGVRCGSDFLVVGNQERNALGMDN-PMAHDTEAAIQ 266 >4M3N-A nrPDB Length = 254 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 58/282 (20%), Positives = 94/282 (33%), Gaps = 62/282 (21%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCV-GGSPNRMKAFALFMHKELGFEE 86 +N Y M I A G V + G P R K A + Sbjct: 16 ENLYFQSMTPHI-------------SAPPGAVAEAILLPGDPLRAKYIAENFLENPVLYN 62 Query: 87 AEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIG 146 ++ YK V GMGIPS SI +HEL++ T+IR+G Sbjct: 63 QVRNMFGYT------GTYKGKRVSVQGTGMGIPSASIYIHELVQF-----YGCKTLIRVG 111 Query: 147 TSGGI-------GIAPGTVVITDIAVDS--FFKPRFEQVILDNIVTRSTELDKELSEELF 197 T+G I + TD ++++ F + + +++ R+ E Sbjct: 112 TAGAITERLKLRDLVIAQAACTDSSINNLRFAGQNYAPIATFDLLRRAYE---------- 161 Query: 198 NCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMES 257 + P VG+ + T FY Q F GV +EME+ Sbjct: 162 --QAQSRGMPVHVGNVLSTDTFYHDQPNPYQLWAQF---------------GVLAVEMEA 204 Query: 258 TVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQ 299 + G++A + +T+ D L + P + + Q Sbjct: 205 AGLYTLAAKFGVQALCI-LTISDHLITGEKTTPQERQETFDQ 245 >2ISC-A nrPDB Length = 239 Score = 150 bits (378), Expect = 7e-37, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 100/262 (38%), Gaps = 39/262 (14%) Query: 54 AMFGD-VKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAI 112 A GD + V + G P R K A + I+ YK P+ + Sbjct: 7 AQVGDFAETVLMCGDPLRAKLIAETYLENPKLVNNVRGIQGYT------GTYKGKPISVM 60 Query: 113 SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGT---VVITDIAVDSF- 168 HGMG+PSI I EL ++ TIIR+GT G I + T V+ T +S Sbjct: 61 GHGMGLPSICIYAEEL-----YSTYKVKTIIRVGTCGAIDMDIHTRDIVIFTSAGTNSKI 115 Query: 169 FKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDG 228 + RF +D+ + D L + +KE+ N P VG T FY Q L Sbjct: 116 NRIRF----MDHDYPATASFDVVC--ALVDAAKEL-NIPAKVGKGFSTDLFYNPQTELAQ 168 Query: 229 ALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQIN 288 + K +L +EMES + L G +A +C T+ D + + Sbjct: 169 LM------NKFHFL---------AVEMESAGLFPIADLYGARAGCIC-TVSDHILHHEET 212 Query: 289 LPHDVLVEYQQRPQLLISNFIR 310 + +Q ++ + I+ Sbjct: 213 TAEERQNSFQNMMKIALEAAIK 234 >4DAO-A nrPDB Length = 253 Score = 141 bits (355), Expect = 4e-34, Method: Composition-based stats. Identities = 52/238 (21%), Positives = 90/238 (37%), Gaps = 35/238 (14%) Query: 62 VCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSI 121 V + G P R K A + E E ++ YK + GMG+PSI Sbjct: 36 VLLPGDPLRAKFIAE------TYLENVECYNEVRGMYGFTGTYKGKKISVQGTGMGVPSI 89 Query: 122 SIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVITDIAVDSFFKPRFEQVILD 179 SI ++ELI+ +IR+G+ G I + V++ A+ S + +V Sbjct: 90 SIYVNELIQ-----SYDVQNLIRVGSCGAIRKDVKVRDVIL---AMTSSTDSQMNRVAFG 141 Query: 180 NIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKL 239 V + D EL + ++ +K+ P VG FY +++ Sbjct: 142 -SVDFAPCADFELLKNAYDAAKD-KGVPVTVGSVFTADQFYNDDSQIE------------ 187 Query: 240 DYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEY 297 + K GV +EME+T + G KA + +T+ D + + + + Sbjct: 188 ----KLAKYGVLGVEMETTALYTLAAKHGRKALSI-LTVSDHVLTGEETTAEERQTTF 240 >3UAY-A nrPDB Length = 235 Score = 127 bits (319), Expect = 5e-30, Method: Composition-based stats. Identities = 46/240 (19%), Positives = 89/240 (37%), Gaps = 34/240 (14%) Query: 62 VCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSI 121 + + G P R K A +++ + YK V GMG+PSI Sbjct: 16 ILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFT------GTYKGKRVSVQGTGMGVPSI 69 Query: 122 SIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITDIAVDSFFKPRFEQVILD 179 SI ++ELI+ +IR+GT G I + V+I A+ + ++ Sbjct: 70 SIYVNELIQ-----SYGVKNLIRVGTCGAIQKDVKVRDVII---AMTACTDSNMNRL-TF 120 Query: 180 NIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKL 239 + + +L ++ ++ E VG+ + FY + + Sbjct: 121 PGFDFAPAANFDLLKKAYDAGTE-KGLHVRVGNVLTADVFY---------------RESM 164 Query: 240 DYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQ 299 D +K+ GV +EME+T + G+ A V +T+ + + + + + + Sbjct: 165 DMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSV-LTVSNHIFTGEETTSEERQTTFNE 223 >3OCC-A nrPDB Length = 239 Score = 119 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 82/250 (32%), Gaps = 34/250 (13%) Query: 50 HNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPV 109 H M V + G P R K A F + ++ ++ YK + Sbjct: 5 HINAEMGDFADVVLMPGDPLRAKFIAE------TFLQDVREVNNVRGMLGFTGTYKGRKI 58 Query: 110 LAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVITDIAVDS 167 + HGMGIPS SI ELI IIR+G+ G + + VVI A Sbjct: 59 SVMGHGMGIPSCSIYAKELI-----TDFGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTD 113 Query: 168 FFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLD 227 R + D E++ + +K VG+ FY ++ Sbjct: 114 SKVNRMR----FKDHDYAAIADFEMTRNAVDAAKA-KGVNVRVGNLFSADLFYTPDPQMF 168 Query: 228 GALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQI 287 + K G+ +EME+ + G KA +C T+ D + + Sbjct: 169 DVM---------------EKYGILGVEMEAAGIYGVAAEFGAKALTIC-TVSDHIRTGEQ 212 Query: 288 NLPHDVLVEY 297 + + Sbjct: 213 TTAAERQTTF 222 >1PR2-A nrPDB Length = 239 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 51/255 (20%), Positives = 84/255 (32%), Gaps = 44/255 (17%) Query: 50 HNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPV 109 H M V + G P R K A ++ +++ + T YK + Sbjct: 5 HINAEMGDFADVVLMPGDPLRAKYIAETFLED---AREVNNVRGMLGFT---GTYKGRKI 58 Query: 110 LAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI-------GIAPGTVVITD 162 + HGMGIPS SI ELI IIR+G+ G + + G TD Sbjct: 59 SVMGHGMGIPSCSIYTKELI-----TDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTD 113 Query: 163 IAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEG 222 V+ I + D ++ + +K + VG+ FY Sbjct: 114 SKVNR---------IRFKDHDFAAIADFDMVRNAVDAAKAL-GIDARVGNLFSADLFYSP 163 Query: 223 QGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRL 282 G + + K G+ +EME+ + G KA +C T+ D + Sbjct: 164 DGEMFDVM---------------EKYGILGVEMEAAGIYGVAAEFGAKALTIC-TVSDHI 207 Query: 283 DCDQINLPHDVLVEY 297 + + + Sbjct: 208 RTHEQTTAAERQTTF 222 >1ODL-A nrPDB Length = 235 Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 55/260 (21%), Positives = 97/260 (37%), Gaps = 37/260 (14%) Query: 53 PAMFGDV-KFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLA 111 A GDV + V + G P R + A + D +YK PV Sbjct: 7 RAHPGDVAERVLLPGDPGRAEWIAK-----TFLQNPRRYN-DHRGLWGYTGLYKGVPVSV 60 Query: 112 ISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVITDIAVDSFF 169 + GMG PS +I++ EL++L ++R+GT+G +APG +++ AV Sbjct: 61 QTTGMGTPSAAIVVEELVRLGAR------VLVRVGTAGAASSDLAPGELIVAQGAVPLDG 114 Query: 170 KPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGA 229 R + D E+ L+ ++ + +P VG FY A Sbjct: 115 TTRQYL----EGRPYAPVPDPEVFRALWRRAEAL-GYPHRVGLVASEDAFYATTPEEARA 169 Query: 230 LCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINL 289 + GV EME++ + + G++ + + + +R+ D Sbjct: 170 WARY---------------GVLAFEMEASALFLLGRMRGVRTGAI-LAVSNRI-GDPELA 212 Query: 290 PHDVLVEYQQRPQLLISNFI 309 P +VL E +R + + Sbjct: 213 PPEVLQEGVRRMVEVALEAV 232 >1VHW-A nrPDB Length = 253 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 56/258 (21%), Positives = 91/258 (35%), Gaps = 35/258 (13%) Query: 45 LGTKTHNLPAMFGD-VKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCM 103 + T ++ A GD V + G P R K A L D++++ T Sbjct: 1 MSLATPHINAQMGDFADVVLMPGDPLRAKYIAENF---LDNAVQVCDVRNMFGYT---GT 54 Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVIT 161 YK + + HGMGIPS SI + ELIK IIR+G+ G + GI VVI Sbjct: 55 YKGRRISVMGHGMGIPSCSIYVTELIK-----DYGVKKIIRVGSCGAVNEGIKVRDVVIG 109 Query: 162 DIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYE 221 A R I + D ++ + + + VG+ FY Sbjct: 110 MGACTDSKVNR----IRFKDHDFAAIADYKMVKA-AEEAAKARGIDVKVGNLFSAELFYT 164 Query: 222 GQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDR 281 + + + G+ +EME+ + G KA +C T+ D Sbjct: 165 PDPSMFDVMDKY---------------GIVGVEMEAAGIYGVAAEYGAKALAIC-TVSDH 208 Query: 282 LDCDQINLPHDVLVEYQQ 299 + + + + + Sbjct: 209 IKTGEQTTSEERQNTFNE 226 >4M7W-A nrPDB Length = 258 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 56/277 (20%), Positives = 89/277 (32%), Gaps = 51/277 (18%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDV-KFVCVGGSPNRMKAFALFMHKELGFEE 86 +N Y M H+ A GDV + + + G P R K A F E Sbjct: 16 ENLYFQSMGTP---HIG---------ANRGDVAETILLPGDPLRAKYIAE------TFLE 57 Query: 87 AEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIG 146 ++ YK V GMG+PSI I HELI +IR+G Sbjct: 58 DVVQYNNVRGMLGFTGTYKGKKVSVQGTGMGVPSIGIYSHELI-----TEFGVKNLIRVG 112 Query: 147 TSGGIG--IAPGTVVITDIAV--DSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKE 202 T+G + VVI A + K RF + +L + + +K Sbjct: 113 TAGSYQEDVKVRDVVIAMSASTDSAINKLRFNGA------DYAPTASSDLVFKAYEIAKA 166 Query: 203 IPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAA 262 G+ + FY K+ + GV +EME+ Sbjct: 167 -KGLNVKAGNVFTSDTFYGDDPN---------------AWKKWAEFGVLCVEMETAQLYT 210 Query: 263 MCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQ 299 G+ A + +T+ D ++ + + + Sbjct: 211 TAAKLGVNALTL-LTISDSFITHEVTSAEERQTTFNE 246 >4LDN-A nrPDB Length = 261 Score = 107 bits (267), Expect = 6e-24, Method: Composition-based stats. Identities = 50/285 (17%), Positives = 88/285 (30%), Gaps = 45/285 (15%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEA 87 +N Y M H++ + + G P R K A L Sbjct: 16 ENLYFQSMSTP---HINAPLDAF--------ADTILMPGDPLRAKLIAETY---LENVVQ 61 Query: 88 EEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGT 147 D++ + T + K + + HGMG PS SI HEL+ IRIG+ Sbjct: 62 VTDVRGMLGFTGEF---KGRKISVMGHGMGAPSASIYFHELM-----TTYKVKNFIRIGS 113 Query: 148 SGGI--GIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPN 205 G I + +++ A R D T + + E L + + Sbjct: 114 CGAIHDDVKLKDLIVAIGASTDSKMNRIRFKDNDFAATANYNMLSECVNTL-----KTTD 168 Query: 206 FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCG 265 LVG+ + FY + + G+ +EME + Sbjct: 169 INYLVGNVFSSDLFYRPDEEQYDMMARY---------------GILGVEMEVNALYSAAA 213 Query: 266 LCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIR 310 A +C T+ D + + + E + + + ++ Sbjct: 214 ENHCNAVALC-TVTDHIKNHEHLTADERRTELHEMINVALDVALK 257 >1JE0-A nrPDB Length = 236 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 34/246 (13%) Query: 62 VCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSI 121 V V G P R A + L + + + T + Y V +HG+G PSI Sbjct: 17 VLVVGDPGR----ARLLSTLLQNPKLTNENRGFLVYTGK---YNGETVSIATHGIGGPSI 69 Query: 122 SIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVITDIAVDSFFKPRFEQVILD 179 +I+L EL L + IR GT+G + I G +I A + F Q + D Sbjct: 70 AIVLEELAMLGAN------VFIRYGTTGALVPYINLGEYIIVTGASYNQGG-LFYQYLRD 122 Query: 180 NIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKL 239 N ST D EL+ +L S N VG+ + FY Sbjct: 123 NACVASTP-DFELTNKLVT-SFSKRNLKYYVGNVFSSDAFYAEDEE-------------- 166 Query: 240 DYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQ 299 ++K+ G +EME + + G K+A V + + D L I + + L + Sbjct: 167 -FVKKWSSRGNIAVEMECATLFTLSKVKGWKSATV-LVVSDNLAKGGIWITKEELEKSVM 224 Query: 300 RPQLLI 305 + Sbjct: 225 DGAKAV 230 >4TYM-A nrPDB Length = 258 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 60/269 (22%), Positives = 98/269 (36%), Gaps = 48/269 (17%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGD-VKFVCVGGSPNRMKAFALFMHKELGFEE 86 +N Y M I A G+ + + G P R K A ++ Sbjct: 16 ENLYFQSMSIHI-------------EAKQGEIADKILLPGDPLRAKFIAENFLEDAVCFN 62 Query: 87 AEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIG 146 ++ YK V + GMG+PSISI ELI T+IR+G Sbjct: 63 TVRNMFGYT------GTYKGHRVSVMGTGMGMPSISIYARELI-----VDYGVKTLIRVG 111 Query: 147 TSGGI--GIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP 204 T+G I I +V+ A + R + D D +L ++ ++ +KE+ Sbjct: 112 TAGAINPDIHVRELVLAQAAATNSNIIRNDWPEFD----FPQIADFKLLDKAYHIAKEM- 166 Query: 205 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 264 + T VG + + FY Q + AL K GV IEME+ + Sbjct: 167 DITTHVGSVLSSDVFYSNQPDRNMALG---------------KLGVHAIEMEAAALYYLA 211 Query: 265 GLCGLKAAVVCVTLLDRLDCDQINLPHDV 293 + A + +T+ D L+ + + + Sbjct: 212 AQHNVNALAM-MTISDNLNNPEEDTSAEE 239 >6F5I-A nrPDB Length = 233 Score = 101 bits (250), Expect = 6e-22, Method: Composition-based stats. Identities = 52/247 (21%), Positives = 82/247 (33%), Gaps = 35/247 (14%) Query: 54 AMFGDVKFVCV-GGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAI 112 A GD C+ G P R+ A ++ ++ YK + + Sbjct: 7 AKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGK------YKGRGISLM 60 Query: 113 SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPG--TVVITDIAVDSFFK 170 HGMGI S +I + ELIK ++RIGT G I G +++ A Sbjct: 61 GHGMGIASCTIYVTELIK-----TYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKT 115 Query: 171 PRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGAL 230 R + S D ELS + +K + VG+ + FY Sbjct: 116 NR----VRFLNHDLSATPDFELSLRAYQTAKRL-GIDLKVGNVFSSDFFY---------- 160 Query: 231 CSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLP 290 + K IEME+ A KA +C ++ D L + P Sbjct: 161 -----SFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLC-SVSDHLITKEALSP 214 Query: 291 HDVLVEY 297 + + + Sbjct: 215 KERVESF 221 >3TL6-A nrPDB Length = 242 Score = 99.6 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 52/256 (20%), Positives = 92/256 (35%), Gaps = 35/256 (13%) Query: 54 AMFGD-VKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAI 112 A +G+ + V + G P R+K A + + + A YK + Sbjct: 16 AKYGEIAETVLMAGDPLRVKLLA-----DTYLTDVVQYNSVRGAVGYT-GYYKGVKLSVQ 69 Query: 113 SHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITDIAVDSFFK 170 +HGMG+PSI I +EL IIRIG++G + G +VI A + Sbjct: 70 AHGMGMPSIGIYAYELFNF-----YGVKRIIRIGSAGAFDESLKLGDIVIGMGA---CYD 121 Query: 171 PRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGAL 230 FE+ D S D +L E + ++++ + VG+ FY+ Sbjct: 122 SNFER-QYDIPGKYSCIADFQLCREAVDAAEKL-GYRYKVGNIYSANYFYDD-------- 171 Query: 231 CSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLP 290 D+ K GV +EME+ + +A + + Sbjct: 172 --------GDHSGAWKKMGVLAVEMEAAALYMIAARARKQALCMLTISDLCYGSGEKMTA 223 Query: 291 HDVLVEYQQRPQLLIS 306 + ++ Q ++ +S Sbjct: 224 EERRTKFTQMMEVALS 239 >4LNH-A nrPDB Length = 266 Score = 97.6 bits (241), Expect = 7e-21, Method: Composition-based stats. Identities = 52/254 (20%), Positives = 87/254 (34%), Gaps = 45/254 (17%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEA 87 +N Y M + + H +V V G P+R+ M E Sbjct: 16 ENLYFQSMSK----------QPHICVDENQVSPYVIVCGEPDRVNRIVELMDNVELLAEN 65 Query: 88 EEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGT 147 E +YK + S G+G PS+ I + EL C +IR+G+ Sbjct: 66 REYRVFN-------GVYKGTTITICSTGIGAPSMIIAVEEL------KLCGATHVIRVGS 112 Query: 148 SGGIG--IAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPN 205 +G + I G +++ + AV + + S L KE+S L N S + Sbjct: 113 AGAMQDHIQLGELIVAEGAVRDEGGSKAY-ISSAYPAYASFALLKEISHFLENQSVK--- 168 Query: 206 FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCG 265 G FY + LC + K G+ +ME++ + Sbjct: 169 --YYFGVVRSHDSFYTDEED---QLCQY-----------WNKKGILGADMETSALFTVGR 212 Query: 266 LCGLKAAVVCVTLL 279 L GL+ A + ++ Sbjct: 213 LRGLQVASILNNVV 226 >4LKR-A nrPDB Length = 256 Score = 92.3 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 90/272 (33%), Gaps = 46/272 (16%) Query: 28 KNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEA 87 +N Y M I + + + V + G P R K A L Sbjct: 16 ENLYFQSMTAHI------NAQPTDF------AETVIMPGDPLRAKYIAETY---LTDAVE 60 Query: 88 EEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGT 147 +++++ T Y+ + + HGMGI S+ + HELI IIRIG+ Sbjct: 61 VTNVRNMLGYT---GYYQGQRISVMGHGMGISSMVLYGHELINFF-----GVKRIIRIGS 112 Query: 148 SGGIG--IAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPN 205 G + V++ A P + + +T L + + + E Sbjct: 113 LGATQQHVEMRDVILAQAAGTDS--PTNAKRSSGYHM--ATSATFSLLHKAYTKANE-KG 167 Query: 206 FPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCG 265 VG+ +Y+ + AL F GV I+ME + Sbjct: 168 ISVKVGNVFSGDLYYDPDEDMIPALERF---------------GVLGIDMEVAGLYGLAH 212 Query: 266 LCGLKAAVVCVTLLDRLDCDQINLPHDVLVEY 297 G+++ + +T+ D + + + + Sbjct: 213 QQGIESLAI-LTVSDHCLTGEETTAQERQLSF 243 >3MB8-A nrPDB Length = 279 Score = 79.2 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 41/215 (19%), Positives = 66/215 (30%), Gaps = 27/215 (12%) Query: 44 DLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCM 103 + + H V + G P R + A K+ E + Sbjct: 6 GMEVQPHIRLRKEDVEPVVIIVGDPARTEEVANMCEKKQELAYNREYRSFR-------VV 58 Query: 104 YKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI---GIAPGTVVI 160 Y + P+ ISHG+G P SI + EL L IIR GT G + + G V + Sbjct: 59 YDSQPITVISHGIGCPGTSIAIEELAYLG------AKVIIRAGTCGSLKPKTLKQGDVCV 112 Query: 161 TDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFY 220 T AV+ + + + L + +KE+ G + FY Sbjct: 113 TYAAVN-----ETGLISNILPEGFPCVATPHVYQALMDAAKEL-GIEAASGIGVTQDYFY 166 Query: 221 -----EGQGRLDGALCSFSREKKLDYLKRAFKAGV 250 + + C + L G+ Sbjct: 167 QNGILPSKLEMYSKCCDVIDMEMSGVLGLCQARGI 201 >3EMV-A nrPDB Length = 253 Score = 78.4 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 51/268 (19%), Positives = 88/268 (32%), Gaps = 37/268 (13%) Query: 48 KTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTG 107 + H V V G P R+ + + E C YK Sbjct: 6 QRHIKLTKAQTTPVVLVVGDPGRVDKVKVLCDSYVDLAYNREYKSVEC-------TYKGQ 58 Query: 108 PVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI---GIAPGTVVITDIA 164 L +SHG+G +I EL+ IIR G+ G + + G + I + A Sbjct: 59 KFLCVSHGVGSAGCAICFEELM------NNGAKVIIRAGSCGSLQPTQMKRGDICICNAA 112 Query: 165 VDSFFKPRFEQVILDNIV-TRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQ 223 V R ++V I D E+ L ++E+ P G ++ + +Y Sbjct: 113 V------REDRVSHLMIYSDFPAVADYEVYATLNQVAEELK-VPVFNGISLSSDMYYP-- 163 Query: 224 GRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLD 283 + L+ KA V +EME M L +K + + L Sbjct: 164 -----------HKIIPTRLEDYSKANVAVVEMEVATLMVMGTLRKVKTGGIFIVDGCPLK 212 Query: 284 CDQINLPHDVLVEYQQRPQLLISNFIRR 311 D+ + ++++ E + + R Sbjct: 213 WDEGDFDNNLVPERLENMIKISLETCAR 240 >5ZNI-A nrPDB Length = 245 Score = 73.8 bits (179), Expect = 8e-14, Method: Composition-based stats. Identities = 45/221 (20%), Positives = 76/221 (34%), Gaps = 37/221 (16%) Query: 61 FVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPS 120 V V G P R+ + + E C YK L +SHG+G Sbjct: 18 VVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECH-------YKGQKFLCVSHGVGSAG 70 Query: 121 ISIMLHELIKLLHHARCCDVTIIRIGTSGGIG---IAPGTVVITDIAVDSFFKPRFEQVI 177 ++ EL + IIR G+ G + I G + I + AV R ++V Sbjct: 71 CAVCFEELCQ------NGAKVIIRAGSCGSLQPDLIKRGDICICNAAV------REDRVS 118 Query: 178 -LDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSRE 236 L D ++ + L C++E+ N P G ++ + +Y + Sbjct: 119 HLLIHGDFPAVGDFDVYDTLNKCAQEL-NVPVFNGISVSSDMYYPN-------------K 164 Query: 237 KKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVT 277 L+ KA +EME + L +K + + Sbjct: 165 IIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGILIV 205 >1NW4-A nrPDB Length = 276 Score = 73.8 bits (179), Expect = 8e-14, Method: Composition-based stats. Identities = 45/221 (20%), Positives = 76/221 (34%), Gaps = 37/221 (16%) Query: 61 FVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPS 120 V V G P R+ + + E C YK L +SHG+G Sbjct: 20 VVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECH-------YKGQKFLCVSHGVGSAG 72 Query: 121 ISIMLHELIKLLHHARCCDVTIIRIGTSGGIG---IAPGTVVITDIAVDSFFKPRFEQVI 177 ++ EL + IIR G+ G + I G + I + AV R ++V Sbjct: 73 CAVCFEELCQ------NGAKVIIRAGSCGSLQPDLIKRGDICICNAAV------REDRVS 120 Query: 178 -LDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSRE 236 L D ++ + L C++E+ N P G ++ + +Y + Sbjct: 121 HLLIHGDFPAVGDFDVYDTLNKCAQEL-NVPVFNGISVSSDMYYPN-------------K 166 Query: 237 KKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVT 277 L+ KA +EME + L +K + + Sbjct: 167 IIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGILIV 207 >3BJE-A nrPDB Length = 349 Score = 69.1 bits (167), Expect = 3e-12, Method: Composition-based stats. Identities = 60/310 (19%), Positives = 105/310 (33%), Gaps = 71/310 (22%) Query: 62 VCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSI 121 + G P R+ + + K+ + GT YK PV IS GMG+ +I Sbjct: 46 IIFVGDPGRVDVISGYFDKDSIRASRDHREIRFATGT-----YKGTPVTVISTGMGVDNI 100 Query: 122 SIMLHELIKLLHHA----------------------RCCDVTIIRIGTSG---------- 149 I+L+E+ L + + IIR+GT G Sbjct: 101 EIVLNEIHALKEYDMERGQWRHRKGDADAPSAGPFFDPSTMKIIRLGTCGSPAESVPPLA 160 Query: 150 ------GIGIAPGTVVITDIAVDSFFKPRF------EQVILDNIVTRSTELDKELSEELF 197 IG+ ++ + ++ + EQ L I ++ +++ + Sbjct: 161 LAVTRHAIGMDNTSLYYSAGTRETSKDQQEIRRIVREQTGLRAIDIYTSMAHPNITKSIC 220 Query: 198 NCS--------KEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSRE-------KKLDYL 242 E ++G T FY QGR + F + ++L L Sbjct: 221 AACDAHNAATGSEADKQQYVIGTTATASGFYGCQGR---RVGRFMKHLTVPNMVEELGSL 277 Query: 243 KRAFKAGVR---NIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQ 299 K GV NIEME++ + + G +A CV + R+ ++ D L + Sbjct: 278 KFNLSNGVEVVTNIEMETSAICYLSDMLGYQAGAACVVVSKRV-GEKKMFLGDQLDAAMK 336 Query: 300 RPQLLISNFI 309 R +I + Sbjct: 337 RCIKIILEAL 346 >4KN5-A nrPDB Length = 253 Score = 44.1 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 36/204 (17%), Positives = 71/204 (34%), Gaps = 24/204 (11%) Query: 109 VLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITDIAVD 166 V+ + G+G + + L L +I G++G +G + G +VI D Sbjct: 65 VVVVESGIGKVASA-----LTTTLLITNFGVDAVINSGSAGALGTDLRIGDIVIADYLAY 119 Query: 167 SFFKPRFEQVILDNIVTRST--ELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQG 224 + R + + + D +LS +L +++ + + G + + F Sbjct: 120 ADADARAFGYAYGQVPQQPARFKADTDLSNDLSESYEKVTDARLVRGLVVTSDSFIASNE 179 Query: 225 RLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDC 284 + L F + EME A + + AVV + D + Sbjct: 180 QKQTILTHFPEAQSA--------------EMEGASIAQVANYFDVPFAVV-RAISDNANG 224 Query: 285 DQINLPHDVLVEYQQRPQLLISNF 308 + D +VE Q+ ++ NF Sbjct: 225 EAGMTFDDFIVEAGQQSAQVLINF 248 >6IF8-A nrPDB Length = 260 Score = 42.2 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 40/256 (15%), Positives = 75/256 (29%), Gaps = 32/256 (12%) Query: 67 SPNRMK-AFALFMHKELGFEEAEEDIKDIC--AGTDRY-CMYKTGPVLAISHGMGIPSIS 122 P MK M +E+ ++ G + Y V+ G+G + S Sbjct: 27 DPEFMKVGIIGAMEQEVALLRSQMSNPTTLQLGGCEFYQGTLAGKEVILTRSGIGKVAAS 86 Query: 123 IMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVITDIAVDSFFKPRFEQVILDN 180 + L++ + +I G++GG + G VVI + Sbjct: 87 VATSLLLE-----KFAPDCVINTGSAGGFAQDLHIGDVVIASEMRFHDVDVTAFGYEMGQ 141 Query: 181 IVTRSTEL--DKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKK 238 + + D+ L +C E T VG F + A F + Sbjct: 142 MAQQPAAFPCDETLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIAKARADFPQ--- 198 Query: 239 LDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQ 298 + +EME +C + K + V + + + D +E Sbjct: 199 -----------MLAVEMEGAAIGQVCHMF--KVPYLVVRAMSDIAGKEQVESFDAFIEVA 245 Query: 299 QRPQLLISNFIRRRLG 314 + + + LG Sbjct: 246 GKHSAEVII---KMLG 258 >4L0M-A nrPDB Length = 259 Score = 40.3 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 24/176 (13%), Positives = 64/176 (36%), Gaps = 26/176 (14%) Query: 106 TGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGI----GIAPGTVVIT 161 V++++ G+G + + ++I ++ II G+SGGI + ++++ Sbjct: 65 GKDVISLTTGIGKVNAATWSSQII-----SKYKITHIINSGSSGGIKENSNLKILDIIVS 119 Query: 162 DIAVDSFFKPRFEQVILDNI--VTRSTELDKELSEELFNCSKE-IPNFPTLVGHTMCTYD 218 F + + + + + D+EL +++ N + N +G + Sbjct: 120 SETAYYDFDLTKFGHKIGQVPNLPQKFKADEELLKKVANIVDNKLLNIDIHIGLILTGDQ 179 Query: 219 FYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVV 274 F + + L+ +F ++ME A + + + ++ Sbjct: 180 FVDNEKNLETIKKNFKD--------------ALAVDMEGAAIAQVAHIFKIPFIII 221 >1ZOS-A nrPDB Length = 230 Score = 39.9 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 36/256 (14%), Positives = 72/256 (28%), Gaps = 33/256 (12%) Query: 59 VKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGI 118 +K + P + + + + ++G I M Sbjct: 1 MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVVLVESG----IGKVMSA 56 Query: 119 PSISIMLHELIKLLHHARCCDVTIIRIGTSGGI--GIAPGTVVITDIAVDSFFKPRFEQV 176 S++I+ +I G++G + GIA G VVI D Sbjct: 57 MSVAILAD---------HFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDVTAFGY 107 Query: 177 ILDNIVTRS--TELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFS 234 + + E DK ++ ++ +G F G +++ F Sbjct: 108 AYGQMAQQPLYFESDKTFVAQIQESLSQLDQ-NWHLGLIATGDSFVAGNDKIEAIKSHFP 166 Query: 235 REKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVL 294 V +EME A L V+ + I + + Sbjct: 167 E--------------VLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFF-DEFI 211 Query: 295 VEYQQRPQLLISNFIR 310 +E +R ++ F++ Sbjct: 212 IEAGRRSAQVLLAFLK 227 >4G41-A nrPDB Length = 236 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 55/173 (31%), Gaps = 23/173 (13%) Query: 105 KTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG--IAPGTVVITD 162 K +L S G+G ++ + L++ II G++G + +A G VV+ D Sbjct: 45 KHELILVQS-GVGKVMSAMTVAILVE-----HFKAQAIINTGSAGAVASHLAIGDVVVAD 98 Query: 163 IAVDSFFKPRFEQVILDNIVTRSTELDKELS-EELFNCSKEIPNFPTLVGHTMCTYDFYE 221 V + + D + +F + VG F Sbjct: 99 RLVYHDVDATAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVA 158 Query: 222 GQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVV 274 GQ ++D +FS V +EME A G VV Sbjct: 159 GQDKIDQIKTAFS--------------NVLAVEMEGAAIAQAAHTAGKPFIVV 197 >4WKO-A nrPDB Length = 245 Score = 34.9 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 23/173 (13%), Positives = 47/173 (27%), Gaps = 27/173 (15%) Query: 102 CMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVIT 161 +Y ++ +G ++ ++ V + S + +++ Sbjct: 53 GVYHNKEIIVAYSKIGKVHSTLTT---TSMILAFGVQKVLFSGVAGSLVKDLKINDLLVA 109 Query: 162 DIAVDSFFKPRFEQVILDNIVTRSTELDK--ELSEELFNCSKEIPNFPTLV---GHTMCT 216 V D+ + E E S L +K+I N + G Sbjct: 110 TQLVQHDVD----LSAFDHPLGFIPESAIFIETSGSLNALAKKIANEQHIALKEGVIASG 165 Query: 217 YDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGL 269 F + R + + F +EME A +C G+ Sbjct: 166 DQFVHSKERKEFLVSEFKAS---------------AVEMEGASVAFVCQKFGV 203 >3EEI-A nrPDB Length = 233 Score = 31.8 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 36/252 (14%), Positives = 77/252 (30%), Gaps = 30/252 (11%) Query: 71 MKAFALFMHKELGFEEAEEDIKDICAGT-DRYCMYKT----GPVLAISHGMGIPSISIML 125 +K A+ E E E ++++ A + R+ Y+ ++ G+G + ++ Sbjct: 3 LKTVAVIGAMEQEIELLREMMENVKAVSFGRFSAYEGELAGKRMVLALSGIGKVNAAVAT 62 Query: 126 HELIKLLHHARCCDVTIIRIGTSGGIGIAPG--TVVITDIAVDSFFKPRFEQVILDNI-- 181 +I+ +I G++GG+G VVI + Sbjct: 63 AWIIR-----EFAADCVINTGSAGGLGKGLKVGDVVIGTETAHHDVDVTAFGYAWGQVPQ 117 Query: 182 VTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDY 241 + D L E ++ G + F + F Sbjct: 118 LPARFASDGILIEAAKRAARTFEGAAVEQGLIVSGDRFVHSSEGVAEIRKHFPE------ 171 Query: 242 LKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRP 301 V+ +EME+ A C L+ V + + ++ ++ D ++ Sbjct: 172 --------VKAVEMEAAAIAQTC--HQLETPFVIIRAVSDSADEKADISFDEFLKTAAAN 221 Query: 302 QLLISNFIRRRL 313 + I + L Sbjct: 222 SAKMVAEIVKSL 233 >3C8E-A nrPDB Length = 288 Score = 31.4 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 33/87 (37%), Gaps = 6/87 (6%) Query: 79 HKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGM-GIPSISIMLHELIKLLHHARC 137 K G A + ++ P+ S G ++IML EL+ L Sbjct: 15 DKSAGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGTPNGQKVTIMLEELLALGVTGAE 74 Query: 138 CDVTIIRIG-----TSGGIGIAPGTVV 159 D +IRIG +SG + + P + + Sbjct: 75 YDAWLIRIGDGDQFSSGFVEVNPNSKI 101 >3HQ9-A nrPDB Length = 345 Score = 31.0 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 27/192 (14%), Positives = 58/192 (30%), Gaps = 5/192 (2%) Query: 71 MKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIK 130 MK ++ + +E D ++K P G P+ + + Sbjct: 1 MKQLSVSLAILCAVATSEAFAADELQ-QRAQGLFKPVPAK-APTLKGNPASPVKVELGKM 58 Query: 131 LLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDK 190 L R +I T +G+ G + T PR +L+++ + D Sbjct: 59 LYFDPRLSASHLISCNTCHNVGLGGGDLQATSTGHGWQKGPRNAPTVLNSVFNTAQFWDG 118 Query: 191 ELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGV 250 +++L +K P + +T + + + F + + F Sbjct: 119 R-AKDLAEQAKGPVQAPVEMNNT--PDQVVKTLNSIPDYVALFKKAFPGEKDPVTFDNMA 175 Query: 251 RNIEMESTVFAA 262 + IE+ Sbjct: 176 KAIEVFEATLIT 187 >1TQY-B nrPDB Length = 415 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 45/158 (28%), Gaps = 15/158 (9%) Query: 84 FEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTII 143 + + TG + HGM PS +++ + L A I Sbjct: 127 LWSEGPKSVSVYESFAWFYAVNTGQISIR-HGMRGPSSALVAEQAGGL--DALGHARRTI 183 Query: 144 RIGT----SGGIG--IAPGTVV--ITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEE 195 R GT SGG+ + P V I + + P + D + Sbjct: 184 RRGTPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERAAGYVPGEGGAILV 243 Query: 196 LFN-CSKEIPNFPTLVGHTM-CTYDF--YEGQGRLDGA 229 L + + E G C F G GR G Sbjct: 244 LEDSAAAEARGRHDAYGELAGCASTFDPAPGSGRPAGL 281 >3K4W-A nrPDB Length = 291 Score = 29.5 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 38/101 (37%), Gaps = 10/101 (9%) Query: 172 RFEQVILDNIVTRSTELDKELS-EELFNCSKEIPNF----PTLVGHTMCTY-----DFYE 221 RF + + + E EL EE+ E +++G Y Sbjct: 31 RFTRQLGFEPAPSAEEKSLELMFEEMAAAGIEQGVCVGRNSSVLGSVSNADVAAVAKAYP 90 Query: 222 GQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAA 262 + G++ + +R++ + ++ G+R + +E V+A Sbjct: 91 DKFHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGVWAT 131 >3LGS-A nrPDB Length = 267 Score = 29.5 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 40/125 (32%), Gaps = 10/125 (8%) Query: 101 YCMYKTGPVLAISHG----MGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGI--- 153 + ++K + + G +GI S+ + LI II GT GG + Sbjct: 66 HGVHKDLRINVVCPGRDAALGIDSVGTVPASLITFASIQALKPDIIINAGTCGGFKVKGA 125 Query: 154 APGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHT 213 G V + V F R + + ++ L + +I T Sbjct: 126 NIGDVFLVSDVV---FHDRRIPIPMFDLYGVGLRQAFSTPNLLKELNLKIGRLSTGDSLD 182 Query: 214 MCTYD 218 M T D Sbjct: 183 MSTQD 187 >5DK6-A nrPDB Length = 265 Score = 29.1 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 54/190 (28%), Gaps = 32/190 (16%) Query: 136 RCCDVTIIRIGTSGGIG--IAPGTVVITDIA----VDSFFKPRFEQVILDNIVTRSTELD 189 R ++ G++GG + G +V++ VD + N D Sbjct: 87 RFQVDYVVNTGSAGGFDASLKVGDIVVSSEVRYHDVDLTAFGYEIGQLPANPAAFMPHDD 146 Query: 190 KELSEELFNCSKEIP-----NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKR 244 L +++ N + G F + + A +F Sbjct: 147 --LVAAAKKGIEQLSQTAGENIKAVTGLITTGDTFMTKEEDVAKARANFPT--------- 195 Query: 245 AFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLL 304 + +EME A C L+ V + D PH EY + + Sbjct: 196 -----MAAVEMEGAAIAQAC----LQLKTPFVVIRSLSDIAGKESPH-TFEEYLETAAVN 245 Query: 305 ISNFIRRRLG 314 S + LG Sbjct: 246 SSQLVLNMLG 255 >2RC9-A nrPDB Length = 294 Score = 28.3 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 34/84 (40%), Gaps = 11/84 (13%) Query: 48 KTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTG 107 + +N+PA V++ + P ++ AF M K L D + D + Sbjct: 197 RRYNVPATPDGVQY--LKNDPEKLDAFI--MDKAL------LDYEVSI-DADCKLLTVGK 245 Query: 108 PVLAISHGMGIPSISIMLHELIKL 131 P +G+G+P S + + +L Sbjct: 246 PFAIEGYGIGLPPNSPLTSNISEL 269 >2QSZ-A nrPDB Length = 207 Score = 28.3 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 23/66 (34%), Gaps = 5/66 (7%) Query: 193 SEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRN 252 + N K +PN + DF++ + ++ F + L+ L + Sbjct: 35 TTLAKNLQKHLPNCSV-----ISQDDFFKPESEIETDKNGFLQYDVLEALNMEKMMSAIS 89 Query: 253 IEMEST 258 MES Sbjct: 90 CWMESA 95 >3MJO-A nrPDB Length = 296 Score = 27.9 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 34/116 (29%), Gaps = 4/116 (3%) Query: 126 HELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRS 185 +L + + I+ GT G I + P + + AV + Sbjct: 61 EQLATMRVFTGLTLLDTIQ-GTVGAISLLPDAETMHEEAVYTNIAFMESVHAKSYSNIFM 119 Query: 186 TELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDY 241 T E F S+E N M +Y G L + S E L Y Sbjct: 120 TLASTPQINEAFRWSEENENLQRKAKIIMS---YYNGDDPLKKKVASTLLESFLFY 172 >3DHZ-A nrPDB Length = 329 Score = 27.9 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 34/116 (29%), Gaps = 4/116 (3%) Query: 126 HELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRS 185 +L + + I+ GT G I + P + + AV + Sbjct: 62 EQLATMRVFTGLTLLDTIQ-GTVGAISLLPDAETMHEEAVYTNIAFMESVHAKSYSNIFM 120 Query: 186 TELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDY 241 T E F S+E N M +Y G L + S E L Y Sbjct: 121 TLASTPQINEAFRWSEENENLQRKAKIIMS---YYNGDDPLKKKVASTLLESFLFY 173 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.116 0.282 Lambda K H 0.267 0.0358 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,812,240 Number of Sequences: 36641 Number of extensions: 352001 Number of successful extensions: 1404 Number of sequences better than 10.0: 50 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 1216 Number of HSP's gapped (non-prelim): 100 length of query: 317 length of database: 10,336,785 effective HSP length: 97 effective length of query: 220 effective length of database: 6,782,608 effective search space: 1492173760 effective search space used: 1492173760 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.2 bits) S2: 59 (27.5 bits)