BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O94788 (518 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4X2Q-A nrPDB 1031 0.0 5AC0-A nrPDB 794 0.0 5AC2-A nrPDB 779 0.0 5FHZ-A nrPDB 770 0.0 1O9J-A nrPDB 757 0.0 1AG8-A nrPDB 733 0.0 5L13-A nrPDB 729 0.0 4PXL-B nrPDB 526 e-149 5GT6-A nrPDB 511 e-145 4PZ2-A nrPDB 508 e-144 3RHO-A nrPDB 479 e-135 4QYJ-A nrPDB 417 e-117 4O5H-A nrPDB 415 e-116 4O6R-A nrPDB 412 e-115 6B4R-B nrPDB 405 e-113 5IUV-A nrPDB 402 e-112 4GO4-A nrPDB 400 e-112 1BPW-A nrPDB 379 e-105 4CAZ-A nrPDB 376 e-104 4V3F-A nrPDB 375 e-104 4MPY-A nrPDB 374 e-104 3IWJ-A nrPDB 373 e-103 2D4E-A nrPDB 362 e-100 3R31-A nrPDB 359 1e-99 3IWK-A nrPDB 358 3e-99 6QAO-A nrPDB 351 4e-97 4I8P-A nrPDB 343 1e-94 4LIH-A nrPDB 343 1e-94 4I8Q-A nrPDB 340 9e-94 5KLK-A nrPDB 330 7e-91 4F3X-A nrPDB 326 2e-89 4YWE-A nrPDB 317 9e-87 1WNB-A nrPDB 315 3e-86 3U4J-A nrPDB 315 3e-86 6MVR-A nrPDB 311 4e-85 3JZ4-A nrPDB 311 5e-85 3I44-A nrPDB 306 2e-83 6C43-A nrPDB 306 2e-83 4U3W-A nrPDB 305 4e-83 4V6H-A nrPDB 300 1e-81 3EK1-A nrPDB 299 2e-81 5J77-A nrPDB 298 4e-81 3TY7-A nrPDB 296 1e-80 4JZ6-A nrPDB 292 2e-79 3B4W-A nrPDB 285 3e-77 3RHD-A nrPDB 273 1e-73 5UR2-A nrPDB 270 1e-72 5EUY-A nrPDB 267 8e-72 6FK3-A nrPDB 263 1e-70 3RJL-A nrPDB 259 1e-69 3QAN-A nrPDB 258 5e-69 2HG2-A nrPDB 256 2e-68 3K2W-A nrPDB 256 2e-68 2W8P-A nrPDB 255 3e-68 3RH9-A nrPDB 250 9e-67 3PRL-A nrPDB 246 2e-65 5X5U-A nrPDB 246 2e-65 1T90-A nrPDB 244 8e-65 5VBF-A nrPDB 239 1e-63 2QE0-A nrPDB 239 3e-63 3R64-A nrPDB 238 4e-63 2J5N-A nrPDB 236 2e-62 4DNG-A nrPDB 226 2e-59 2JG7-A nrPDB 225 3e-59 3VZ3-A nrPDB 225 3e-59 5N5S-A nrPDB 219 2e-57 1UXV-A nrPDB 218 4e-57 3VZ0-A nrPDB 216 2e-56 4X0T-A nrPDB 214 7e-56 5JRY-A nrPDB 213 1e-55 4KNA-A nrPDB 212 4e-55 3EFV-A nrPDB 211 6e-55 5KF0-A nrPDB 211 8e-55 5TJR-A nrPDB 211 9e-55 5U0M-A nrPDB 207 9e-54 4I3V-A nrPDB 204 6e-53 4OGD-A nrPDB 204 7e-53 3ROS-A nrPDB 203 1e-52 5J6B-A nrPDB 202 4e-52 4PXN-A nrPDB 198 5e-51 4ZZ7-A nrPDB 197 8e-51 4E4G-A nrPDB 177 1e-44 4H7N-A nrPDB 174 1e-43 6DBB-A nrPDB 169 4e-42 3JU8-A nrPDB 162 3e-40 5UCD-A nrPDB 150 2e-36 4OE4-A nrPDB 149 3e-36 3V9H-A nrPDB 148 6e-36 3SZA-A nrPDB 146 2e-35 4LGZ-A nrPDB 146 2e-35 1AD3-A nrPDB 139 2e-33 4QGK-A nrPDB 134 1e-31 4IDS-A nrPDB 115 4e-26 5NNO-A nrPDB 110 2e-24 2Y53-A nrPDB 85 8e-17 6D97-A nrPDB 59 4e-09 5UJU-A nrPDB 50 3e-06 3V4C-A nrPDB 49 6e-06 5DBV-A nrPDB 49 7e-06 5J7I-A nrPDB 47 2e-05 1EZ0-A nrPDB 43 3e-04 3MY7-A nrPDB 40 0.002 5JFN-A nrPDB 37 0.022 3K9D-A nrPDB 36 0.035 3IP1-A nrPDB 32 0.73 1WKO-A nrPDB 29 4.2 2AW5-A nrPDB 29 5.4 2CBU-A nrPDB 29 5.7 1TF2-A nrPDB 28 9.0 5EUL-A nrPDB 28 10.0 >4X2Q-A nrPDB Length = 504 Score = 1031 bits (2666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 498/498 (100%), Positives = 498/498 (100%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA Sbjct: 7 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 66 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL Sbjct: 67 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 126 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA Sbjct: 127 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 186 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA Sbjct: 187 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 246 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC Sbjct: 247 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 306 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA Sbjct: 307 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 366 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN Sbjct: 367 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 426 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL Sbjct: 427 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 486 Query: 501 REYSEVKTVTVKIPQKNS 518 REYSEVKTVTVKIPQKNS Sbjct: 487 REYSEVKTVTVKIPQKNS 504 >5AC0-A nrPDB Length = 501 Score = 794 bits (2051), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/493 (74%), Positives = 438/493 (88%) Query: 26 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 +P+P NL+ KYTKIFINNEW +S SG+ FPV+NPAT E++CEV+E DK D+DKAV+AAR Sbjct: 9 VPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAAR 68 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 AF +GS WR MDASERGRLL+KLADL+ERDR +LATME++NGGK F A+ +DL G IK Sbjct: 69 QAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLGGCIK 128 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 T RY AGWADKI G TIP+DG++FT+TR EP+GVCGQIIPWNFPLLMF WKI PAL CGN Sbjct: 129 TLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGN 188 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 TVV+KPAEQTPL+AL+MG+LIKEAGFPPGV+NI+PGYGPTAGAAI+SH+ +DK+AFTGST Sbjct: 189 TVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGST 248 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 EVGKLI+EAAG+SNLKRV+LELGGKSP I+FADADLD AVE AHQGVF++QGQCC A SR Sbjct: 249 EVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASR 308 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 +FVEESIY+EFVRRSVERAK+ V+G+P P QGPQIDK+QY KIL+LI+SG EGAKL Sbjct: 309 LFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKL 368 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 ECGG G KG+FI+PTVFS+VTDDMRIAKEEIFGPVQ+I++FK++D+VI+RANN+ +GL Sbjct: 369 ECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGL 428 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 A +FTNDI+KA+TVSSA+Q+GTVW+NCY+ ++AQ PFGGFKMSGNGRE+GE+G EY+E Sbjct: 429 SAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFHEYTE 488 Query: 506 VKTVTVKIPQKNS 518 VKTVT+KI QKNS Sbjct: 489 VKTVTIKISQKNS 501 >5AC2-A nrPDB Length = 501 Score = 779 bits (2012), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/493 (73%), Positives = 431/493 (87%) Query: 26 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 LP +L+I+YTKIFINNEW +S SG+ FPV+NPAT E++C+V+E DK D+DKAV+AAR Sbjct: 9 LPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAAR 68 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 AF +GS WR MDASERGRLL KLADL+ERDR +LATMES+NGGK + A+ DL G IK Sbjct: 69 QAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIK 128 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 T RY AGWADKI G TIP+DG++FT+TRHEPIGVCGQIIPWNFPL+M WKI PAL CGN Sbjct: 129 TLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGN 188 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 TVV+KPAEQTPL+AL++ +LIKEAGFPPGV+NI+PGYGPTAGAAI+SH+ IDK+AFTGST Sbjct: 189 TVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGST 248 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 EVGKLI+EAAG+SNLKRVTLELGGKSP I+ ADADLD AVE AH GVF++QGQCC A SR Sbjct: 249 EVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASR 308 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 IFVEESIY+EFVRRSVERAK+ ++G+P P QGPQIDK+QY+KIL+LI+SG EGAKL Sbjct: 309 IFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKL 368 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 ECGG G KG+F++PTVFSNVTD+MRIAKEEIFGPVQ+I++FK++D+VI+RANN+ +GL Sbjct: 369 ECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGL 428 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 A VFT DI+KA+T+SSA+QAGTVW+NCY ++AQ PFGGFKMSGNGRE+GE+G EY+E Sbjct: 429 SAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTE 488 Query: 506 VKTVTVKIPQKNS 518 VKTVTVKI QKNS Sbjct: 489 VKTVTVKISQKNS 501 >5FHZ-A nrPDB Length = 529 Score = 770 bits (1988), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/492 (71%), Positives = 424/492 (86%) Query: 26 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 LP P NLE+K+TKIFINNEW S+SG+ F NP+T EQ+CEV+E DK D+DKAV+AA+ Sbjct: 37 LPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQ 96 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 +AF GS WRR+DA RGRLL +LADLVERDRA LA +E+++ GKPFL AF++DL+G I+ Sbjct: 97 VAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIR 156 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 T RY+AGWADKI G TIP D + FTRHEPIGVCG I PWNFPLLM WK+APALCCGN Sbjct: 157 TLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGN 216 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 T+V+KPAEQTPL+ALY+G+LIKEAGFPPGV+NI+PG+GPT GAAI+SH I+KIAFTGST Sbjct: 217 TMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 276 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 EVGKL++EAA RSNLKRVTLELGGK+P I+ ADADLD AVE AHQGVFFNQGQCCTA SR Sbjct: 277 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 336 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 +FVEE +Y EFVRRSVE AK+R VG PFD TEQGPQID+KQ++KILELI+SG EGAKL Sbjct: 337 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL 396 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 ECGG + KG FI+PTVFS VTD+MRIAKEEIFGPVQ IL+FK+++EVI+RAN++D+GL Sbjct: 397 ECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 456 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 AAVFT +++KAL ++SA+++GTVWINCYNAL AQ+PFGGFKMSGNGRE+GE+ L EY+E Sbjct: 457 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTE 516 Query: 506 VKTVTVKIPQKN 517 VKTVT+K+ KN Sbjct: 517 VKTVTIKLGDKN 528 >1O9J-A nrPDB Length = 501 Score = 757 bits (1955), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/493 (70%), Positives = 426/493 (86%) Query: 26 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 LP+P N++I++TK+FINNEW S SG+ FPV+NPAT E++CEV+EADK D+DKAV+AAR Sbjct: 9 LPAPLTNIKIQHTKLFINNEWHESVSGKTFPVFNPATEEKICEVEEADKEDVDKAVKAAR 68 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 AF +GS WR MDASERG+L+ KLADL+ERDR +LAT+ES+N GK F A+ +DL IK Sbjct: 69 EAFQMGSPWRTMDASERGQLIYKLADLIERDRLLLATLESINAGKVFASAYLMDLDYCIK 128 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 RY AGWADKI G TIPVDG++F++TRHEPIGVCG I PWN P+++ A KI PALCCGN Sbjct: 129 ALRYCAGWADKIQGRTIPVDGEFFSYTRHEPIGVCGLIFPWNAPMILLACKIGPALCCGN 188 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 TV++KPAEQTPL+AL++ +LIKEAGFPPGV+NI+PGYGPTAGAAI+SH+ +DK+AFTGST Sbjct: 189 TVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGST 248 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 EVGK+IQEAA +SNLKRVTLELG K+P I+FADADLD AVE AHQGVF NQGQ C A S+ Sbjct: 249 EVGKMIQEAAAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAASK 308 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 +FVEE+IY+EFV+RSVERAK+ V G+P P GPQI+K Q+NKI+ELI+SG EGAKL Sbjct: 309 LFVEEAIYDEFVQRSVERAKKYVFGNPLTPGVNHGPQINKAQHNKIMELIESGKKEGAKL 368 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 ECGG G KG+FI+PTVFSNVTDDMRIAKEEIFGPVQ+I++FK++DEVI+RANN+ +GL Sbjct: 369 ECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTYYGL 428 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 VA VFT D++KA+TVSSA+QAGTVW+NCY A +AQSP GGFKMSG+GREMGE+G+ EY+E Sbjct: 429 VAGVFTKDLDKAVTVSSALQAGTVWVNCYLAASAQSPAGGFKMSGHGREMGEYGIHEYTE 488 Query: 506 VKTVTVKIPQKNS 518 VKTVT+KI +KNS Sbjct: 489 VKTVTMKISEKNS 501 >1AG8-A nrPDB Length = 499 Score = 733 bits (1892), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/498 (66%), Positives = 411/498 (82%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 A+ +P+P E+ Y +IFINNEW ++ S + FP NP+TG+ +C V E DKAD+D+A Sbjct: 2 AATQAVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTVNPSTGDVICHVAEGDKADVDRA 61 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V+AAR AF LGS WRRMDASERGRLL++LADL+ERDR LA +E+L+ GKP++ ++ VDL Sbjct: 62 VKAARAAFQLGSPWRRMDASERGRLLNRLADLIERDRTYLAALETLDNGKPYIISYLVDL 121 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 V+K RYYAGWADK HG TIP+DGDYF++TRHEP+GVCGQIIPWNFPLLM AWK+ PA Sbjct: 122 DMVLKCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPA 181 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 L GN VV+K AEQTPL+ALY+ LIKEAGFPPGV+N++PG+GPTAGAAIASH +DK+A Sbjct: 182 LATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIASHEDVDKVA 241 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTEVG LIQ AAG+SNLKRVTLE+GGKSPNII +DAD+D+AVEQAH +FFNQGQCC Sbjct: 242 FTGSTEVGHLIQVAAGKSNLKRVTLEIGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCC 301 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 AGSR FV+E IY EFV RSV RAK RVVG+PFD TEQGPQ+D+ Q+ K+L I+SG Sbjct: 302 CAGSRTFVQEDIYAEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKVLGYIKSGKE 361 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EG KL CGG +G+FI+PTVF ++ D M IAKEEIFGPV +IL+FK+M+EV+ RANN Sbjct: 362 EGLKLLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSMEEVVGRANN 421 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 S +GL AAVFT D++KA +S A+QAGTVW+NCY+ AQSPFGG+K+SG+GRE+GE+GL Sbjct: 422 SKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGSGRELGEYGL 481 Query: 501 REYSEVKTVTVKIPQKNS 518 + Y+EVKTVTV++PQKNS Sbjct: 482 QAYTEVKTVTVRVPQKNS 499 >5L13-A nrPDB Length = 517 Score = 729 bits (1881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/498 (67%), Positives = 410/498 (82%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 A+ +P+P E+ +IFINNEW ++ S + FP NP+TGE +C+V E DK D+DKA Sbjct: 20 AATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKA 79 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V+AAR AF LGS WRRMDAS RGRLL++LADL+ERDR LA +E+L+ GKP++ ++ VDL Sbjct: 80 VKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDL 139 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 V+K RYYAGWADK HG TIP+DGD+F++TRHEP+GVCGQIIPWNFPLLM AWK+ PA Sbjct: 140 DMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPA 199 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 L GN VV+K AEQTPL+ALY+ LIKEAGFPPGV+NI+PG+GPTAGAAIASH +DK+A Sbjct: 200 LATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVA 259 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTE+G++IQ AAG SNLKRVTLELGGKSPNII +DAD+D+AVEQAH +FFNQGQCC Sbjct: 260 FTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCC 319 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 AGSR FV+E IY+EFV RSV RAK RVVG+PFD TEQGPQ+D+ Q+ KIL I +G Sbjct: 320 CAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQ 379 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EGAKL CGG +G+FI+PTVF +V D M IAKEEIFGPV +IL+FKT++EV+ RANN Sbjct: 380 EGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANN 439 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 S +GL AAVFT D++KA +S A+QAGTVW+NCY+ AQSPFGG+KMSG+GRE+GE+GL Sbjct: 440 STYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGL 499 Query: 501 REYSEVKTVTVKIPQKNS 518 + Y+EVKTVTVK+PQKNS Sbjct: 500 QAYTEVKTVTVKVPQKNS 517 >4PXL-B nrPDB Length = 517 Score = 526 bits (1354), Expect = e-149, Method: Compositional matrix adjust. Identities = 244/483 (50%), Positives = 343/483 (71%), Gaps = 1/483 (0%) Query: 31 PNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL 90 P +E+++TK+FI+ ++ ++ SG+ F +P TGE + + E DKAD+D AV+AAR AF Sbjct: 30 PKVEVRFTKLFIDGKFVDAVSGKTFETRDPRTGEVIASIAEGDKADVDLAVKAAREAFDN 89 Query: 91 GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYY 150 G W RM ERGR+L + ADL++ LA +++++ GK F D+ G RYY Sbjct: 90 GP-WPRMTGYERGRILHRFADLIDEHVEELAALDTVDAGKLFAVGKARDIPGAAHLLRYY 148 Query: 151 AGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 AG ADK+HG T+ + +T EP+GV G I+PWN+P MF +K+ PAL G VV+K Sbjct: 149 AGAADKVHGATLKMAQRMHGYTLKEPVGVVGHIVPWNYPTTMFFFKVGPALAAGCAVVVK 208 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 PAEQTPLSAL+ L +EAG P GV+N++PG+GPTAGAA+A+H+ +DK++FTGSTEVG+L Sbjct: 209 PAEQTPLSALFYAHLAREAGVPAGVLNVVPGFGPTAGAAVAAHMDVDKVSFTGSTEVGRL 268 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 + AA SNLK V+LELGGKSP I+F DADLD AV + + N+G+ C AG+RI+V+E Sbjct: 269 VMRAAAESNLKPVSLELGGKSPVIVFDDADLDMAVNLVNFATYTNKGEICVAGTRIYVQE 328 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 IY+EFV+++ E A + VVG PF+P+ QGPQ+DK QY K+L I G EGA L GGK Sbjct: 329 GIYDEFVKKAAELASKSVVGDPFNPSVSQGPQVDKDQYEKVLRYIDIGKREGATLVTGGK 388 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 G KG++IEPT+F++V DDM IA++EIFGPV +++FKT++EVI++ANN+ +GL A + Sbjct: 389 PCGDKGYYIEPTIFTDVKDDMTIAQDEIFGPVMALMKFKTVEEVIQKANNTRYGLAAGIV 448 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 T +I+ A TVS +++AG +WINCY A + +PFGG+KMSG G++MG L +Y + KTV Sbjct: 449 TKNIDVANTVSRSIRAGAIWINCYFAFDPDAPFGGYKMSGFGKDMGMDALDKYLQTKTVV 508 Query: 511 VKI 513 + Sbjct: 509 TPL 511 >5GT6-A nrPDB Length = 508 Score = 511 bits (1317), Expect = e-145, Method: Compositional matrix adjust. Identities = 251/475 (52%), Positives = 323/475 (68%), Gaps = 2/475 (0%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K+FIN E+ ++ G+ F YNPAT + + V EA + DID AV+AAR AF G W M Sbjct: 35 KMFINGEFVSAIGGKTFETYNPATEDVLAVVCEAQEEDIDAAVKAARSAFESGP-WAEMT 93 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +ER L+ KLADL+E R LA +E+L+ GKP+ A D+ ++ +RYYAGW KI Sbjct: 94 TAERAHLIYKLADLIEEHREELAQLEALDNGKPYQVALDDDISATVENYRYYAGWTTKII 153 Query: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 G TIP+ DY +TRHEP+GV GQIIPWNFPL+M +WK+ AL G T+V+KPAEQTPLS Sbjct: 154 GQTIPISKDYLNYTRHEPVGVVGQIIPWNFPLVMSSWKMGAALATGCTIVLKPAEQTPLS 213 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 LY L KEAGFP GV+N +PG+GP AGAAI +H IDK+AFTGST GK I + Sbjct: 214 LLYAAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKVAFTGSTVTGKYIMRQSAEM 273 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 +K VTLELGGKSPNII DADL+ A+ A QG+ +N GQ C+AGSR+FV YE V Sbjct: 274 -IKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQNCSAGSRVFVHRKHYETVVD 332 Query: 339 RSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFF 398 V+ A +G+ + TE GP + KKQ ++L I+ G EGA + GG+ KG+F Sbjct: 333 ALVKMANNVKLGAGMEKETEMGPLVSKKQQERVLNYIEQGKKEGATVAAGGERALEKGYF 392 Query: 399 IEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKAL 458 ++PTVF++VTDDM I KEEIFGPV +L F + +EVIERANNS +GL A V+T +I Sbjct: 393 VKPTVFTDVTDDMTIVKEEIFGPVVVVLPFDSTEEVIERANNSSYGLAAGVWTQNIKTGH 452 Query: 459 TVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 V++ ++AGTVWIN YN NA +PFGG+K SG GRE+G + L Y+EVK+V V I Sbjct: 453 QVANKLKAGTVWINDYNLENAAAPFGGYKQSGIGRELGSYALDNYTEVKSVWVNI 507 >4PZ2-A nrPDB Length = 534 Score = 508 bits (1308), Expect = e-144, Method: Compositional matrix adjust. Identities = 256/483 (53%), Positives = 333/483 (68%), Gaps = 4/483 (0%) Query: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93 EI++TK+FIN + ++ SGR F +P TG + V EADK D+D AV+AAR AF G Sbjct: 47 EIRFTKLFINGSFVDAVSGRTFDTRDPRTGGVIASVAEADKEDVDLAVRAARAAFDHGE- 105 Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153 W RM SERGR++ +LADLVE LA +ESL+ GK VD+ + RY+AG Sbjct: 106 WPRMSGSERGRIMARLADLVEEHAGELAALESLDAGKHPAVTRAVDVGNAAGSLRYFAGA 165 Query: 154 ADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 ADKIHG T+ + G + T EP+GV G IIPWNFP MFA K+APAL G +V+KPAE Sbjct: 166 ADKIHGETLKMPGQFQGHTLREPLGVAGVIIPWNFPSTMFAVKVAPALAAGCALVVKPAE 225 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 QTPLSALY+ L K+AG P GVIN++PG+GPTAGAA+ASH+ +D ++FTGSTEVG+LI + Sbjct: 226 QTPLSALYLAQLAKQAGVPDGVINVVPGFGPTAGAALASHMDVDMVSFTGSTEVGRLIMK 285 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 A+ SNLK V LELGGKSP I+F DADLD AVE A FFN+G+ C A SR++V+E +Y Sbjct: 286 ASAESNLKPVYLELGGKSPLIVFDDADLDMAVELAVGASFFNKGEACVAASRVYVQERVY 345 Query: 334 EEFVRRSVERAKRRVVGSPF-DPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL 392 + F R ER + VVG PF DP +QGPQ+DK QY ++L I G EGA L GG+ Sbjct: 346 DRFEERLAERMRSWVVGDPFSDPRADQGPQVDKAQYERVLSYIDHGKREGATLLTGGRPC 405 Query: 393 G--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 KG++IEPTVF+NV +DM IAKEEIFGPV +++FKT++E I RAN++ +GL A V Sbjct: 406 APEGKGYYIEPTVFTNVKEDMIIAKEEIFGPVMCLMKFKTVEEAIARANDTRYGLGAGVV 465 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 T D++ A V +++AG VW+NCY A+ + PFGG KMSG G++ G L +Y VK+V Sbjct: 466 TRDLDVANRVVRSVRAGVVWVNCYFAMGSDCPFGGRKMSGFGKDEGMHALDKYLAVKSVV 525 Query: 511 VKI 513 + Sbjct: 526 TPL 528 >3RHO-A nrPDB Length = 517 Score = 479 bits (1233), Expect = e-135, Method: Compositional matrix adjust. Identities = 238/484 (49%), Positives = 325/484 (67%), Gaps = 8/484 (1%) Query: 33 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGS 92 L++ Y ++FI E+ ++E + + NP G +C+V A +D+DKAV AA+ AF G Sbjct: 33 LQMPY-QLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENG- 90 Query: 93 VWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAG 152 +W +++A +RGRLL +LAD++E+ + LAT+E+L+ G + A + I+TFRY+AG Sbjct: 91 LWGKINARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAG 150 Query: 153 WADKIHGMTIPVD----GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 W DKI G TIP++ T T+ EP+GVCG +IPWN+PL+M +WK A L GNTVV Sbjct: 151 WCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVV 210 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 IKPA+ TPL+AL L +AG P GV+NILPG G G ++ H + KI FTGSTEVG Sbjct: 211 IKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVG 270 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 K I ++ SN+K+V+L+LGGKSP IIFAD DL+ AV+ VFFN+G+ C A R+FV Sbjct: 271 KHIMKSCALSNVKKVSLQLGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFV 330 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 EESI+ +FV++ VE ++ +G+P + T GPQ + K++E Q GV EGA L CG Sbjct: 331 EESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCG 390 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFK--TMDEVIERANNSDFGLV 446 G + R GFF +PTVF++V D M IAKEE FGP+ I RF +D V+ RAN ++FGL Sbjct: 391 GNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLA 450 Query: 447 AAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEV 506 + VFT DINKAL VS +QAGTV+IN YN + +PFGGFK SG G+++GE L EY + Sbjct: 451 SGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRI 510 Query: 507 KTVT 510 KTVT Sbjct: 511 KTVT 514 >4QYJ-A nrPDB Length = 516 Score = 417 bits (1073), Expect = e-117, Method: Compositional matrix adjust. Identities = 217/482 (45%), Positives = 309/482 (64%), Gaps = 12/482 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGS-VWRRM 97 ++ I +W +++SG+ VYNPATG+ + EV + D D++ AV++A A +L S WRRM Sbjct: 36 QMLIGGQWVSAQSGKTLNVYNPATGDILTEVPDGDVEDVNAAVESA--AATLRSDTWRRM 93 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 S R R+L +LADL+E LA +E+LN GK + + +++ + RY AGWA K+ Sbjct: 94 PPSARERILLRLADLLEVHGDELARLETLNNGKLLIYSKLMEVGASAQWLRYMAGWATKL 153 Query: 158 HGMTI------PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 G T+ P + T+ P+GV IIPWNFPLLM WKIAPAL CGNTVV+KP Sbjct: 154 TGSTLDLSLPLPPEVRSRASTQRVPVGVVAAIIPWNFPLLMAVWKIAPALACGNTVVLKP 213 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 AE+TPL+AL + L EAG P G +N++ G G TAG A+ H + K+AFTGSTEVG++I Sbjct: 214 AEETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDALVRHPKVAKVAFTGSTEVGRII 273 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331 A GRS LK V+LELGGKSP I+ AD D A E A +FFN GQ CTAGSR++V ES Sbjct: 274 GSACGRS-LKAVSLELGGKSPVIVLADCDPQEAAEGAAAAIFFNHGQVCTAGSRLYVHES 332 Query: 332 IYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG-K 390 IYE+ ++R + VVGS + GP + KK + +L I++G+ +GA L CGG + Sbjct: 333 IYEDVIQRLAVIGESIVVGSGLEQGVHMGPMVSKKHHENVLRHIRNGIEDGADLICGGTE 392 Query: 391 GLGRKGFFIEPTVFSNV-TDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 +GFF++PT+F+N D+R+ +E+FGPV F + EV+ AN S +GL A++ Sbjct: 393 APCAQGFFVKPTIFANREKKDIRLLSQEVFGPVLVATPFSDIAEVVNEANRSVYGLGASI 452 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 +TND++ AL ++ ++AGTVW+N +N ++ PFGGFK SG GRE G + Y+ +++ Sbjct: 453 WTNDLSAALRINDELEAGTVWVNTHNMVDPNLPFGGFKDSGVGREHGAAAIEHYTTTRSL 512 Query: 510 TV 511 + Sbjct: 513 VI 514 >4O5H-A nrPDB Length = 511 Score = 415 bits (1067), Expect = e-116, Method: Compositional matrix adjust. Identities = 226/483 (46%), Positives = 306/483 (63%), Gaps = 8/483 (1%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 K ++ I EW ++ SGR V NPA G + V EAD+ D+ +AV AAR AF G WR Sbjct: 29 KPKQMLIGAEWSDAASGRQLDVVNPADGTVIARVPEADERDVQQAVAAARRAFDAGP-WR 87 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 ++R RL+ LADL+E + LA +ESL+ GKP + A +D+ + FRY AGWA Sbjct: 88 TAKTTDRERLMLVLADLIEANARELAEIESLDNGKPVMVAQGLDVAMAAQCFRYMAGWAT 147 Query: 156 KIHGMTIPV------DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 KI G I D + F +TR EP+GV G IIPWNFPLLM AWKIAPAL G TVV+ Sbjct: 148 KIEGSVIDAGMPYLPDSEIFAYTRKEPVGVVGAIIPWNFPLLMAAWKIAPALATGCTVVL 207 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPAE TPLSAL +G LI+ AGFP GV+NI+ GYG TAGAA++ IDKIAFTGST+ GK Sbjct: 208 KPAEDTPLSALRLGELIQAAGFPDGVVNIVTGYGHTAGAALSRDPRIDKIAFTGSTQTGK 267 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 I AA N+ R++LELGGKSP I+ D DLD A + +FFNQGQ CTAGSR ++ Sbjct: 268 TIGHAA-LDNMTRMSLELGGKSPVIVLPDVDLDKAAQGVANAIFFNQGQVCTAGSRAYIH 326 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 +++ + R + A +G DP T+ GP + KQ ++ I SG EGA+ GG Sbjct: 327 SKVFDGVIERVAKIAASLKIGPGMDPATQIGPLVSAKQRERVCGYIDSGFGEGARAAAGG 386 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 + + GFF+EPTV + T MR+ +EEIFGPV + F +D ++ AN++ +GL A++ Sbjct: 387 RAIDGPGFFVEPTVLVDTTQAMRVVREEIFGPVLVAMPFDDVDTAVQLANDTPYGLGASI 446 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 ++ND++ + + AGTVW+NC++ L+ PFGG K SG GRE+G + +Y+E K+V Sbjct: 447 WSNDLSAIHKLVPRIAAGTVWVNCHSLLDNALPFGGMKQSGFGRELGRAVIDQYTESKSV 506 Query: 510 TVK 512 + Sbjct: 507 MMN 509 >4O6R-A nrPDB Length = 496 Score = 412 bits (1058), Expect = e-115, Method: Compositional matrix adjust. Identities = 208/480 (43%), Positives = 295/480 (61%), Gaps = 8/480 (1%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 T++FI+ + ++ V NP G + ++ A AD+D AV AA AF W M Sbjct: 11 TQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAFP---AWSAM 67 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 A+ERGRLL +LAD +E + LA +ESL+ G P + +D+ FRY+ G ADK+ Sbjct: 68 PAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKL 127 Query: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G IPVD + + + PIGV GQI+PWNFPL+ +WK+ PAL GNTVV+KP+E TPL Sbjct: 128 QGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPL 187 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 S L + L+ E GFP GV+NI+PGYG TAG +A H G+ KIAFTGST G+ I EA+ + Sbjct: 188 STLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEAS-Q 246 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 NLKRV LELGGK NI+F DA+LD A+ A +F NQGQ C AGSR+ + E I + F+ Sbjct: 247 GNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFL 306 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG----LG 393 R V A +G+P DP TE GP K+ +++L + +G ++ GG Sbjct: 307 ERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPAL 366 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 G+++ PT+ R+A+EE+FGP +LRF + DE + AN +++GL + ++TND Sbjct: 367 ANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTND 426 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 +++A +++ + AG WINCY +N SPFGG SG GREMG + +Y+E ++V V + Sbjct: 427 LSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNV 486 >6B4R-B nrPDB Length = 497 Score = 405 bits (1041), Expect = e-113, Method: Compositional matrix adjust. Identities = 203/478 (42%), Positives = 302/478 (63%), Gaps = 4/478 (0%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + F+N E+ N+ SG F +P G + +V D AD ++AV+ AR AF G+ W R+ Sbjct: 21 RAFVNGEYSNAASGETFDCLSPVDGRFLAKVASCDLADAEQAVKVARNAFDSGA-WSRLA 79 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ++R + + + ADL+ + LA +E+L+ GKP + ++D+ + R+ A DKI+ Sbjct: 80 PAKRKQTMIRFADLLLENAEELALLETLDMGKPISDSLHIDVASAANSLRWSAEAIDKIY 139 Query: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 EP+GV I+PWNFPLLM WK+ PAL GN+V++KP+E++PL+ Sbjct: 140 DEVAATPHAELGLVTREPVGVVAAIVPWNFPLLMSCWKLGPALATGNSVILKPSEKSPLT 199 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 A+ + L EAG P GV N+LPGYG T G A+A H+ +D + FTGST++ K + AG S Sbjct: 200 AIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHMDVDTLVFTGSTKIAKQLMVYAGES 259 Query: 279 NLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 N+KRV LE GGKSPNI+FADA DL A E A + FNQG+ CTAGSR+ VE SI ++F+ Sbjct: 260 NMKRVWLEAGGKSPNIVFADAPDLKAAAEAAAGAIAFNQGEVCTAGSRLLVERSIKDKFL 319 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK-- 395 +E K G+P DP T G +D +Q N +L I++G +GAKL GGK + Sbjct: 320 PLVIEALKGWKPGNPLDPETNVGALVDTQQMNTVLSYIEAGHNDGAKLVAGGKRTLEETG 379 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 G ++EPT+F VT+ M+IA+EEIFGPV ++ F+ +E + AN++ +GL AAV+T++++ Sbjct: 380 GTYVEPTIFDGVTNAMKIAREEIFGPVLSVIEFEDAEEAVRIANDTPYGLAAAVWTSNLS 439 Query: 456 KALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 KA + A++AG+VW+N Y+ + +PFGGFK SGNGR+ +Y+E+K +K+ Sbjct: 440 KAHLTAKALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELKATWIKL 497 >5IUV-A nrPDB Length = 497 Score = 402 bits (1034), Expect = e-112, Method: Compositional matrix adjust. Identities = 205/485 (42%), Positives = 304/485 (62%), Gaps = 5/485 (1%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 NL+I+ + FI E+ + SG F +P G + +V D AD +AV++AR AF G Sbjct: 15 NLKIE-GRAFIQGEYTAAASGETFDCISPVDGRLLAKVASCDAADAQRAVESARSAFDSG 73 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 + W R+ ++R + + A L+E++ LA +E+L+ GKP + VD+ G + + Sbjct: 74 A-WSRLAPAKRKATMIRFAGLLEQNAEELALLETLDMGKPISDSLGVDIPGGARALSWSG 132 Query: 152 GWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 DK++ D EP+GV I+PWNFPL+M WK+ PAL GN+VV+KP Sbjct: 133 EAIDKLYDEVAATPHDQLGLVTREPVGVVAAIVPWNFPLMMACWKLGPALSTGNSVVLKP 192 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 +E++PL+A+ + L EAG P GV+N+LPGYG T G A+A H+ +D + FTGST++ K + Sbjct: 193 SEKSPLTAIRIAQLAIEAGIPAGVLNVLPGYGHTVGKALALHMDVDTVVFTGSTKIAKQL 252 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 AG SN+KRV LE GGKSPNI+FADA DL A + A + FNQG+ CTAGSR+ VE Sbjct: 253 MIYAGESNMKRVWLEAGGKSPNIVFADAPDLQAAADSAASAIAFNQGEVCTAGSRLLVER 312 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 SI + F+ +E G+P DP T G +D +Q N +L I +G +GA+L GGK Sbjct: 313 SIKDRFLPMVIEALGTWKPGNPLDPATNVGALVDTQQMNTVLSYIAAGHTDGARLVAGGK 372 Query: 391 GLGRK--GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 + ++ G ++EPT+F V + MRIA+EEIFGPV +L F T +E I+ AN++ +GL AA Sbjct: 373 QILQETGGTYVEPTIFDGVNNAMRIAQEEIFGPVLSVLTFDTAEEAIQIANDTPYGLAAA 432 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 V+T +++KA + A++AG+VW+N Y+ + +PFGGFK SGNGR+ +Y+E+K+ Sbjct: 433 VWTANLSKAHLTARALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELKS 492 Query: 509 VTVKI 513 +K+ Sbjct: 493 TWIKL 497 >4GO4-A nrPDB Length = 495 Score = 400 bits (1028), Expect = e-112, Method: Compositional matrix adjust. Identities = 208/483 (43%), Positives = 302/483 (62%), Gaps = 9/483 (1%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 +++I+ + ++ +G V +P G + + A+ AD+D AV AA+ AF W + Sbjct: 3 NQLYIDGRFVDAVAGGTIDVVSPHDGSLITRIAAAEAADVDLAVAAAKRAFP---AWSAL 59 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 A+ERGRLL KLAD +E LA +ESLN G P + +D+ FRY+ G ADKI Sbjct: 60 GAAERGRLLLKLADRIEECSEELAQLESLNTGHPIRDSRGLDVPRTAACFRYFGGMADKI 119 Query: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G IPVD + + + +PIGV QI+PWNFPL+ +WK+ PAL GNT+VIKP+E TPL Sbjct: 120 EGSVIPVDAGFLNYVQRKPIGVVAQIVPWNFPLMFTSWKMGPALAAGNTIVIKPSEITPL 179 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 S L + L+ E GFP GV+N++PGYG TAG A+A H+ + KIAFTGST G+ I EA+ + Sbjct: 180 STLRIVELMTEVGFPKGVVNVVPGYGHTAGQALAEHLDVGKIAFTGSTATGRRIVEAS-K 238 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 SNLKR+ LELGGK NI+F DA+++ AV A +F NQGQ C AGSR+ + + I ++F+ Sbjct: 239 SNLKRIQLELGGKGANIVFEDANIEAAVNGAAWAIFHNQGQACIAGSRLILHKDIADQFL 298 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK-- 395 R + AK +G P DP TE GP + +++L I + +G K+ GGK K Sbjct: 299 ERFIALAKSIRLGDPMDPETEMGPLTSALRRDRVLSYIDIAIEQGGKVLAGGKAPDDKAL 358 Query: 396 --GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 GF++EPTV D R+ +EE+FGP ++RF + +E + ANN+++GL + ++T + Sbjct: 359 ANGFYVEPTVVEAKPQD-RVCQEEVFGPFVTVVRFSSDEEALAIANNTEYGLGSGLWTQN 417 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 + +A ++ A+ AG WINCY ++ SPFGG SG GREMG + +Y+E ++V V + Sbjct: 418 LARAHKMAHAIHAGMCWINCYKRVSPGSPFGGVGQSGYGREMGFEAIHDYTEARSVWVNV 477 Query: 514 PQK 516 K Sbjct: 478 DAK 480 >1BPW-A nrPDB Length = 503 Score = 379 bits (974), Expect = e-105, Method: Compositional matrix adjust. Identities = 193/469 (41%), Positives = 284/469 (60%), Gaps = 12/469 (2%) Query: 56 PVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVER 115 PV+ PATG +C++ ++D+AVQ+A+ A+ W +M ER R++ + A ++ Sbjct: 39 PVFEPATGRVLCQMVPCGAEEVDQAVQSAQAAYLK---WSKMAGIERSRVMLEAARIIRE 95 Query: 116 DRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHE 175 R +A +E +N GK +A Y D+ + YYAG A + G I + G F +TR E Sbjct: 96 RRDNIAKLEVINNGKTITEAEY-DIDAAWQCIEYYAGLAPTLSGQHIQLPGGAFAYTRRE 154 Query: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 P+GVC I+ WN+P ++ AWK APAL CGN VV KP+ TP++ + + + EAG P G+ Sbjct: 155 PLGVCAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGVILAEIFHEAGVPVGL 214 Query: 236 INILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNII 295 +N++ G G G+ + H + K++FTGS GK + E + ++ +K VTLELGGKSP +I Sbjct: 215 VNVVQG-GAETGSLLCHHPNVAKVSFTGSVPTGKKVMEMSAKT-VKHVTLELGGKSPLLI 272 Query: 296 FADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDP 355 F D +L+ AV A F QGQ CT G+R+FV+ I +F+ V+R K VVG P Sbjct: 273 FKDCELENAVRGALMANFLTQGQVCTNGTRVFVQREIMPQFLEEVVKRTKAIVVGDPLLT 332 Query: 356 TTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG------RKGFFIEPTVFSNVTD 409 T G I K Q +K+L + EGA++ CGG+ L + G+F+ P V N D Sbjct: 333 ETRMGGLISKPQLDKVLGFVAQAKKEGARVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRD 392 Query: 410 DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTV 469 DM KEEIFGPV +L F T +EV++RANN+ FGL + VFT DI++A V++ ++AGT Sbjct: 393 DMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDISRAHRVAANLEAGTC 452 Query: 470 WINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 518 +IN Y+ + PFGG+KMSG GRE G+ + YS++KTV V++ +S Sbjct: 453 YINTYSISPVEVPFGGYKMSGFGRENGQATVDYYSQLKTVIVEMGDVDS 501 >4CAZ-A nrPDB Length = 490 Score = 376 bits (966), Expect = e-104, Method: Compositional matrix adjust. Identities = 198/479 (41%), Positives = 276/479 (57%), Gaps = 7/479 (1%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K++I + + SG F NPA GE + +VQ A + D+++AVQ+A VW M Sbjct: 8 KLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSA---VEGQKVWAAMT 64 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 A +R R+L + D++ LA +E+L+ GKP + VD+ YYAG I Sbjct: 65 AMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIE 124 Query: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 G IP+ F +TR EP+GV I WN+P+ + WK APAL GN ++ KP+E TPL+ Sbjct: 125 GEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPLT 184 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 AL + + EAG P GV N+L G G G + H I+KI+FTG T GK + +A S Sbjct: 185 ALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASSS 244 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 +LK VT+ELGGKSP IIF DADLD A + A FF+ GQ CT G+R+F+ S F Sbjct: 245 SLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEA 304 Query: 339 RSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK----GLGR 394 + +ER +R +G P D T GP + +L I+SG A+ A+L CGG+ G Sbjct: 305 KVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAFG 364 Query: 395 KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDI 454 KG ++ PTVF++ DDM I +EEIFGPV IL + DE I RAN++++GL A V T D+ Sbjct: 365 KGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQDL 424 Query: 455 NKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 +A ++AG WIN + A+ P GG+K SG GRE G L Y+ +K+V V++ Sbjct: 425 ARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVEL 483 >4V3F-A nrPDB Length = 497 Score = 375 bits (964), Expect = e-104, Method: Compositional matrix adjust. Identities = 197/486 (40%), Positives = 291/486 (59%), Gaps = 11/486 (2%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 I ++FI+ EW+ PV NP+T E + ++ A D++ AV AAR AF + W Sbjct: 5 IPARQLFIDGEWREPIKKNRIPVINPSTEEIIGDIPAATAEDVEVAVVAARRAFRRNN-W 63 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 + R L +A + + +E+++ GKPF +A +D+ V F Y+AG A Sbjct: 64 SATSGAHRATYLRAIAAKITEKKDHFVKLETIDSGKPFDEAV-LDIDDVASCFEYFAGQA 122 Query: 155 DKIHG-----MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 + + G +T+P++ + + +P+GV G I PWN+PLLM WKIAPAL G T V+ Sbjct: 123 EALDGKQKAPVTLPME-RFKSHVLRQPLGVVGLISPWNYPLLMATWKIAPALAAGCTAVL 181 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KP+E ++ L G + E G PPGV+NIL G GP AGA + SH +DKIAFTGS+ G Sbjct: 182 KPSELASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDVDKIAFTGSSATGS 241 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 + +A + +K VTLELGGKSP ++F D D+D VE G F+ GQ C+A SR+ V Sbjct: 242 KVMASAAQL-VKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTNGQICSATSRLLVH 300 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 ESI EFV + V+ K + PF+ GP I K QY+KI++ I + +EGA + GG Sbjct: 301 ESIAAEFVDKLVKWTKNIKISDPFEEGCRLGPVISKGQYDKIMKFISTAKSEGATILYGG 360 Query: 390 KGLG--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVA 447 +KG++IEPT+ ++++ M+I KEE+FGPV + F + DE I AN++++GL A Sbjct: 361 SRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTFSSEDEAIALANDTEYGLAA 420 Query: 448 AVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVK 507 AVF+ND+ + ++ A++ G VW+NC Q+P+GG K SG GRE+GE+G++ Y +K Sbjct: 421 AVFSNDLERCERITKALEVGAVWVNCSQPCFVQAPWGGIKRSGFGRELGEWGIQNYLNIK 480 Query: 508 TVTVKI 513 VT I Sbjct: 481 QVTQDI 486 >4MPY-A nrPDB Length = 520 Score = 374 bits (961), Expect = e-104, Method: Compositional matrix adjust. Identities = 202/469 (43%), Positives = 286/469 (60%), Gaps = 10/469 (2%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 +I+ EW S + + NP E + V E K D ++A+ AAR AF G W + A Sbjct: 36 YIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGE-WSQETAE 94 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 RG+ + +AD ++ R LA +E+L+ GK L+ Y D+ + F Y+AG ADK G Sbjct: 95 TRGKKVRAIADKIKEHREALARLETLDTGKT-LEESYADMDDIHNVFMYFAGLADKDGGE 153 Query: 161 TI--PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 I P+ D + EP+GV QI PWN+PLL +WKIAPAL G ++V+KP+E TPL+ Sbjct: 154 MIDSPIP-DTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLT 212 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 + + L++E GFP G IN++ G G G ++ H +D ++FTG E GK I + A + Sbjct: 213 TIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAA-N 271 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 N+ + LELGGK+PNIIF DAD + AV+QA G +F+ GQ C+AGSRI V+ SI ++F + Sbjct: 272 NVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQ 331 Query: 339 RSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK--- 395 ++R K+ +G+ FD TE GP I + NKI + AEGA + GGK R Sbjct: 332 ALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLK 391 Query: 396 -GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDI 454 G F EPTV +N MRI +EE+FGPV + F+T E I+ AN+S +GL AVF+ DI Sbjct: 392 DGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDI 451 Query: 455 NKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREY 503 KA V++ ++ GTVWIN ++ AQ+P+GG+K SG GRE+G+ GL EY Sbjct: 452 GKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEY 500 >3IWJ-A nrPDB Length = 503 Score = 373 bits (957), Expect = e-103, Method: Compositional matrix adjust. Identities = 209/493 (42%), Positives = 295/493 (59%), Gaps = 10/493 (2%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL- 90 ++ I ++FIN +W+ + PV NPAT + ++ A K D+D AV AA+ A + Sbjct: 2 DIPIPTRQLFINGDWKAPVLNKRIPVINPATQNIIGDIPAATKEDVDVAVAAAKTALTRN 61 Query: 91 -GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 G+ W + R R L +A V + LA +ES++ GKP +A + D+ V F Y Sbjct: 62 KGADWATASGAVRARYLRAIAAKVTEKKPELAKLESIDCGKPLDEAAW-DIDDVAGCFEY 120 Query: 150 YAGWADKIHG-MTIPVDGDYFTFTRH---EPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 YA A+K+ PV TF H EPIGV G I PWN+P+LM WK+APAL G Sbjct: 121 YADLAEKLDARQKAPVSLPMDTFKSHVLREPIGVVGLITPWNYPMLMATWKVAPALAAGC 180 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 ++KP+E L+ L +G + KE G PPGV+NIL G GP AGA +A+H +DK+AFTGS+ Sbjct: 181 AAILKPSELASLTCLELGEICKEVGLPPGVLNILTGLGPEAGAPLATHPDVDKVAFTGSS 240 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 G I AA + +K V+LELGGKSP ++F D DLD A E A G F+ GQ C+A SR Sbjct: 241 ATGSKIMTAAAQL-VKPVSLELGGKSPLVVFEDVDLDKAAEWAIFGCFWTNGQICSATSR 299 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 + + ESI EF+ R V+ K + P + GP + + QY KIL+ + + +EGA + Sbjct: 300 LILHESIATEFLNRIVKWIKNIKISDPLEEGCRLGPVVSEGQYEKILKFVSNAKSEGATI 359 Query: 386 ECGGKGLG--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDF 443 GG +KGFFIEPT+ ++VT +M+I +EE+FGPV + F T +E I+ AN++ + Sbjct: 360 LTGGSRPEHLKKGFFIEPTIITDVTTNMQIWREEVFGPVLCVKTFSTEEEAIDLANDTVY 419 Query: 444 GLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREY 503 GL AAV +ND+ + V+ A +AG VW+NC Q+P+GG K SG GRE+GE+GL Y Sbjct: 420 GLGAAVISNDLERCERVTKAFKAGIVWVNCSQPCFTQAPWGGVKRSGFGRELGEWGLDNY 479 Query: 504 SEVKTVTVKIPQK 516 VK VT I ++ Sbjct: 480 LSVKQVTQYISEE 492 >2D4E-A nrPDB Length = 515 Score = 362 bits (930), Expect = e-100, Method: Compositional matrix adjust. Identities = 196/484 (40%), Positives = 292/484 (60%), Gaps = 19/484 (3%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 FI E+ SESG FP +PAT E + + ++D+A +AA AF W R A Sbjct: 30 FIAGEFVPSESGETFPSLDPATNEVLGVAARGGEREVDRAAKAAHEAFQR---WSRTKAK 86 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 ER R L ++A+L+E+ LA ME L+ G+ L+ + + F +YA +A+ H M Sbjct: 87 ERKRYLLRIAELIEKHADELAVMECLDAGQ-VLRIVRAQVARAAENFAFYAEYAE--HAM 143 Query: 161 ---TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 T PVD D+ +T P G G I PWN PL++ W+IAPAL GNTVV+KPAE +P Sbjct: 144 EDRTFPVDRDWLYYTVRVPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVLKPAEWSPF 203 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 +A + ++KEA PPGV N++ G+G AGAA+ +H + + TG TE GK++ A Sbjct: 204 TATKLAEILKEADLPPGVFNLVQGFGEEAGAALVAHPLVPLLTLTGETETGKIVMRNAA- 262 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 +LKR++ ELGGKSP ++FADADL+ A++ +F G+ CTA SR+ VEE I+E+FV Sbjct: 263 DHLKRLSPELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVEEKIFEDFV 322 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG---- 393 + VERA+ VG P DP TE GP I + ++L +++G EGA+L GG+ Sbjct: 323 GKVVERARAIRVGHPLDPETEVGPLIHPEHLQRVLGYVEAGKREGARLLVGGERAKTSFR 382 Query: 394 ----RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 +G ++ PTVF + M+IA+EEIFGPV + FK +E + +AN++ +GL A V Sbjct: 383 GEDLSRGNYLLPTVFVG-ENHMKIAQEEIFGPVLVAIPFKDEEEALRKANDTKYGLAAYV 441 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 FT D+ +A ++ ++AG V++N +N + +PFGG K SG+ RE G + L Y+++KT+ Sbjct: 442 FTRDLERAHRLALELEAGMVYLNSHNVRHLPTPFGGVKGSGDRREGGTYALDFYTDLKTI 501 Query: 510 TVKI 513 + + Sbjct: 502 ALPL 505 >3R31-A nrPDB Length = 517 Score = 359 bits (922), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 193/475 (40%), Positives = 278/475 (58%), Gaps = 10/475 (2%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 FI+ ++ +G F PATGE + ++ A A +++A+ +A+ A W M Sbjct: 18 FIDGDYVEDNTGTPFESIFPATGEMIAKLHAATPAIVERAIASAKRA---QKEWAAMSPM 74 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA-DKIHG 159 RGR+L + AD++ L+T+E+L+ GKP + D F ++ G A ++G Sbjct: 75 ARGRILKRAADIMRERNDALSTLETLDTGKPIQETIVADPTSGADAFEFFGGIAPSALNG 134 Query: 160 MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 IP+ GD F +T+ P+GVC I WN+P + WK APAL GN +V KP+E TPL A Sbjct: 135 DYIPLGGD-FAYTKRVPLGVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSENTPLGA 193 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 L + ++ EAG P G+ N++ G T G + +H + K++ TGS G+ + AA + Sbjct: 194 LKIAEILIEAGLPKGLFNVIQGDRDT-GPLLVNHPDVAKVSLTGSVPTGRKVAAAAA-GH 251 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 LK VT+ELGGKSP I+F DAD++ AV A G F++ GQ C+ G+R+FV++ F+ Sbjct: 252 LKHVTMELGGKSPMIVFDDADIESAVGGAMLGNFYSSGQVCSNGTRVFVQKKAKARFLEN 311 Query: 340 SVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG---KGLGRKG 396 R + ++G P D T GP + K Q K+L I+ G AEGA L GG + +G Sbjct: 312 LKRRTEAMILGDPLDYATHLGPLVSKAQQEKVLSYIEKGKAEGATLITGGGIPNNVAGEG 371 Query: 397 FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINK 456 +++PTVF++VTDDM IA+EEIFGPV +L F DEV+ RAN ++FGL VFT D+ + Sbjct: 372 AYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDDEDEVLARANATEFGLAGGVFTADLAR 431 Query: 457 ALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 A V ++AGT+WIN YN + PFGG K SG GRE L YSE+KTV V Sbjct: 432 AHRVVDGLEAGTLWINTYNLCPVEIPFGGSKQSGFGRENSAAALEHYSELKTVYV 486 >3IWK-A nrPDB Length = 503 Score = 358 bits (919), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 199/487 (40%), Positives = 288/487 (59%), Gaps = 12/487 (2%) Query: 33 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL-- 90 + + ++FI+ EW+ + P NP+T + ++ A K D+D AV AA+ A S Sbjct: 3 ITVSSRQLFIDGEWRVPILNKRIPNINPSTENIIGDIPAATKEDVDLAVDAAKRAISRKN 62 Query: 91 GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYY 150 G W S R R L +A ++ + L +ES++ GKP +A DL V+ F YY Sbjct: 63 GRDWSAASGSLRARYLRAIAAKIKEKKDELGKLESIDCGKPLEEAL-ADLDDVVACFEYY 121 Query: 151 AGWADKIHG-----MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 AG A+++ +++P+D + ++ EPIGV I PWN+P LM WKIAPAL G Sbjct: 122 AGLAEELDSKQKAPISLPMD-TFKSYILKEPIGVVALITPWNYPFLMATWKIAPALAAGC 180 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 ++KP+E ++ L +G + KE G P GV+NI+ G G AGA++ASH +DKI+FTGS+ Sbjct: 181 AAILKPSELASVTCLELGEICKEVGLPRGVLNIVTGLGHEAGASLASHPDVDKISFTGSS 240 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 G I A + +K V+LELGGKSP ++F D DLD E G FF GQ C+A SR Sbjct: 241 ATGSKIMTTAAQL-VKPVSLELGGKSPIVVFEDVDLDKVAEWTVFGCFFTNGQICSATSR 299 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 + V ESI EFV + V+ A+ + P + GP + + QY K+L I S +EGA + Sbjct: 300 LIVHESIAVEFVDKLVKWAENIKISDPLEEGCRLGPIVSEAQYKKVLNCISSAKSEGATI 359 Query: 386 ECGGKGLG--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDF 443 GG+ +KG+F+EPT+ ++VT M+I +EE+FGPV + F T +E I AN++ + Sbjct: 360 LTGGRRPEHLKKGYFVEPTIITDVTTSMQIWREEVFGPVLAVKTFSTEEEAINLANDTHY 419 Query: 444 GLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREY 503 GL +AV +ND+ + +S A+QAG VWINC Q+P+GG K SG GRE+GE+GL Y Sbjct: 420 GLGSAVMSNDLERCERLSKALQAGIVWINCAQPSFIQAPWGGIKRSGFGRELGEWGLENY 479 Query: 504 SEVKTVT 510 VK VT Sbjct: 480 LSVKQVT 486 >6QAO-A nrPDB Length = 508 Score = 351 bits (900), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 187/462 (40%), Positives = 270/462 (58%), Gaps = 12/462 (2%) Query: 58 YNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDR 117 + PATG + + + +++ AVQ A+ AF +W + ER R+L + A ++ Sbjct: 46 FEPATGRVIATFTCSGEKEVNLAVQNAKAAFK---IWSQKSGMERCRILLEAARIIRERE 102 Query: 118 AVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPI 177 +ATME +N GK +A +D+ + YYAG A + G I + G F +TR EP+ Sbjct: 103 DEIATMECINNGKSIFEA-RLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPL 161 Query: 178 GVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVIN 237 GVC I WN+P + +WK APAL CGN +V KP+ TP+SAL + + EAG PPG+ N Sbjct: 162 GVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFN 221 Query: 238 ILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFA 297 ++ G G G + H + K++FTGS G I E + + +K VTLELGGKSP IIF+ Sbjct: 222 VVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAK-GIKPVTLELGGKSPLIIFS 279 Query: 298 DADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTT 357 D D++ AV+ A F QGQ C G+R+FV++ I ++F V++ +R +G P T Sbjct: 280 DCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDT 339 Query: 358 EQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG------RKGFFIEPTVFSNVTDDM 411 GP I++ ++L ++ +GAK+ CGG + G+++ P V +N DDM Sbjct: 340 RMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDM 399 Query: 412 RIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWI 471 KEEIFGPV IL F T EV+ERAN++ FGL A VFT DI +A V + +QAGT +I Sbjct: 400 TCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFI 459 Query: 472 NCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 N YN + PFGG+K SG GRE G + YS++KTV V++ Sbjct: 460 NNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEM 501 >4I8P-A nrPDB Length = 520 Score = 343 bits (880), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 199/484 (41%), Positives = 276/484 (57%), Gaps = 10/484 (2%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR--LAFSLGS 92 + ++F++ EW+ GR PV NP T + E+ D+D AV AAR L + G Sbjct: 22 VPLRQLFVDGEWRPPAQGRRLPVVNPTTEAHIGEIPAGTAEDVDAAVAAARAALKRNRGR 81 Query: 93 VWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAG 152 W R + R + L +A V + LA +E+L+ GKP+ +A + D+ V F Y+A Sbjct: 82 DWARAPGAVRAKYLRAIAAKVIERKPELAKLEALDCGKPYDEAAW-DMDDVAGCFEYFAD 140 Query: 153 WADKIHG-MTIPVDGDYFTFTRH---EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 A+ + PV TF H EPIGV G I PWN+PLLM WKIAPAL G T V Sbjct: 141 QAEALDKRQNSPVSLPMETFKCHLRREPIGVVGLITPWNYPLLMATWKIAPALAAGCTAV 200 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 +KP+E ++ L + + KE G P GV+NI+ G GP AGA +++H +DK+AFTGS E G Sbjct: 201 LKPSELASVTCLELADICKEVGLPSGVLNIVTGLGPDAGAPLSAHPDVDKVAFTGSFETG 260 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 K I +A +K VTLELGGKSP ++F D D+D AVE G F+ GQ C+A SR+ + Sbjct: 261 KKIMASAA-PMVKPVTLELGGKSPIVVFDDVDIDKAVEWTLFGCFWTNGQICSATSRLLI 319 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 I ++F R V AK V P + GP + + QY KI + I + ++GA + G Sbjct: 320 HTKIAKKFNERMVAWAKNIKVSDPLEEGCRLGPVVSEGQYEKIKKFISNAKSQGATILTG 379 Query: 389 G--KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLV 446 G KGFFIEPT+ +++T M I +EE+FGPV + F T DE IE AN++ +GL Sbjct: 380 GVRPAHLEKGFFIEPTIITDITTSMEIWREEVFGPVLCVKEFSTEDEAIELANDTQYGLA 439 Query: 447 AAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEV 506 AV + D + +S + AG +W+NC Q+P+GG K SG GRE+GE G+ Y V Sbjct: 440 GAVISGDRERCQRLSEEIDAGCIWVNCSQPCFCQAPWGGNKRSGFGRELGEGGIDNYLSV 499 Query: 507 KTVT 510 K VT Sbjct: 500 KQVT 503 >4LIH-A nrPDB Length = 504 Score = 343 bits (879), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 202/486 (41%), Positives = 297/486 (61%), Gaps = 9/486 (1%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 +LEI+ + FI+ +++ GR F +P G + +V + +AD++ AV AAR AF G Sbjct: 23 SLEIE-GRAFIDGASRDAHGGRTFDCVSPIDGRVLAKVADCGEADVNAAVAAARRAFDAG 81 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 VW ++ R +L + A L+ L+ +E+L+ GKP VD+ G ++A Sbjct: 82 -VWAGLNPRARKAVLLRWAALMREHLDELSLLETLDAGKPIGDTTTVDVPGAAYCVEWFA 140 Query: 152 GWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 DK+ G P D EP+GV ++PWNFP+LM AWK PAL GN+VV+KP Sbjct: 141 EAIDKVGGEVAPADHHLVGLVTREPVGVVAAVVPWNFPILMAAWKFGPALAAGNSVVLKP 200 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 +E++PL+A+ + L EAG P GV N++PG G G +A H +D IAFTGST VGKLI Sbjct: 201 SEKSPLTAIRVAQLAFEAGIPAGVFNVVPGAG-EPGKLLALHRDVDCIAFTGSTAVGKLI 259 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 + A +SNLKR LELGGKSPNI+ D DLD A + A +F+N G+ CTAGSR+ V Sbjct: 260 MQYAAQSNLKRAWLELGGKSPNIVLPDCPDLDRAAQTAAGAIFYNMGEMCTAGSRLLVHR 319 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 I + F+ + V A+ V G+P DP+ G +D Q ++L I++G EG +L GG Sbjct: 320 DIKDAFIEKLVAAARAYVPGNPLDPSVSMGAIVDGIQLERVLGYIEAGRGEG-RLVTGGA 378 Query: 391 GLGRK--GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 + + GF++EPTVF V D +IA+EEIFGPV ++ F +DE + AN++++GL AA Sbjct: 379 RVNAETGGFYVEPTVF-EVKPDAKIAREEIFGPVLSVIVFDDVDEAVRIANDTEYGLAAA 437 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYN-ALNAQSPFGGFKMSGNGREMGEFGLREYSEVK 507 V+T+++ A VS ++AGTVW+NCY+ + PFGG+K SGNGR+ L +Y+E+K Sbjct: 438 VWTSNLTTAHDVSRRLRAGTVWVNCYDEGGDMNFPFGGYKQSGNGRDKSLHALEKYTELK 497 Query: 508 TVTVKI 513 + +++ Sbjct: 498 STLIRL 503 >4I8Q-A nrPDB Length = 514 Score = 340 bits (872), Expect = 9e-94, Method: Compositional matrix adjust. Identities = 189/486 (38%), Positives = 284/486 (58%), Gaps = 10/486 (2%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 N+ I +++I EW+ P+ NPAT E + ++ A D+D AV+AAR A + Sbjct: 18 NVPIPRRQLYIGGEWREPVKKNRIPIINPATEEIIGDIPAATAEDVDIAVEAARKAIARD 77 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 W ++R + L +A V ++VLAT+ESL+ GK ++ D+ V F YYA Sbjct: 78 D-WGSTTGAQRAKYLRAIAAKVLEKKSVLATLESLDSGKTLYES-AADMDDVAGCFEYYA 135 Query: 152 GWADKIHGMTI-PVD---GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTV 207 G A+ + + PV+ Y ++ EP+GV G I PWN+PLLM WK+APAL G Sbjct: 136 GLAEALDSRRMTPVNLNSDSYKSYVLREPLGVVGLITPWNYPLLMAIWKVAPALAAGCAA 195 Query: 208 VIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEV 267 ++KP+E ++ L +G + +E G P G +NIL G GP AG +ASH +DKI+FTGS Sbjct: 196 ILKPSELASITCLELGEICREIGLPSGALNILTGLGPEAGGPLASHPHVDKISFTGSGPT 255 Query: 268 GKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD-LDYAVEQAHQGVFFNQGQCCTAGSRI 326 G I AA + +K V+L LGGKSP ++F D D LD A E G+F N GQ C+A SR+ Sbjct: 256 GSKIMTAAAQL-VKPVSLALGGKSPIVVFDDIDNLDIAAEWTLFGIFANTGQVCSATSRL 314 Query: 327 FVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLE 386 V+E+I F+ R ++ K + P + + GP + QY K+L+ I + +EGA + Sbjct: 315 IVQENIASAFMDRLLKWTKNIKISDPLEEDCKLGPVVSAGQYEKVLKFISNAKSEGATIL 374 Query: 387 CGGKGLG--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG 444 CGG+ +KG++++PT+ ++V M I KEE+FGPV + FKT ++ IE AN++ +G Sbjct: 375 CGGERPQHLKKGYYVQPTIITDVNTSMEIWKEEVFGPVLCVKTFKTEEQAIELANDTKYG 434 Query: 445 LVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYS 504 L AAV + D+ + + A Q G +WINC + P+GG K SG GR++G++GL + Sbjct: 435 LGAAVMSKDVKRCERFTKAFQTGIIWINCSQPTFNELPWGGKKRSGFGRDLGKWGLENFL 494 Query: 505 EVKTVT 510 +K VT Sbjct: 495 NIKQVT 500 >5KLK-A nrPDB Length = 520 Score = 330 bits (847), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 178/474 (37%), Positives = 268/474 (56%), Gaps = 15/474 (3%) Query: 51 SGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLA 110 S F NP G+ + +V EAD +++AV AA+ A L W ++ +R L+ K+A Sbjct: 51 SASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNA--LKGPWGKLSVQDRAALIHKIA 108 Query: 111 DLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG----MTIPVDG 166 D ++ E + G+P QA +D+ I FR +A A H M+ Sbjct: 109 DGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGS 168 Query: 167 DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALI 226 +T +P+GV G I PW+ PLL+F WK+APAL CGNTVV KP+E++P SA + ++ Sbjct: 169 GALNYTVRKPLGVIGVISPWDLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVM 228 Query: 227 KEAGFPPGVINILPGYGP-TAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTL 285 +AG PPGV N++ G+G +AG + H GI + FTG ++ G I +A +K V+ Sbjct: 229 HDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVA-DGVKEVSF 287 Query: 286 ELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAK 345 ELGGK+ ++FADADLD A+E + F N GQ C R++V SI++EFV A+ Sbjct: 288 ELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAE 347 Query: 346 RRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGR------KGFFI 399 R VVG P GP I +K+L + V EGA + GG G+ + +G ++ Sbjct: 348 RLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGG-GVPKFNDERDQGAYV 406 Query: 400 EPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALT 459 +PT+++ ++D R EEIFGPV I F DEVI R N+S++GL A++T ++++A Sbjct: 407 QPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHR 466 Query: 460 VSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 VS + G VW+N + + ++PFGG K+SG GRE G F + YS++ + +KI Sbjct: 467 VSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 520 >4F3X-A nrPDB Length = 498 Score = 326 bits (835), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 172/461 (37%), Positives = 262/461 (56%), Gaps = 13/461 (2%) Query: 57 VYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERD 116 + NP TG + ++ EA A ID AV AA AF +G W + +ER L K+AD +E++ Sbjct: 44 ILNPRTGAGIIDLAEASHAQIDAAVDAAERAF-VG--WSQTTPAERSNALLKIADAIEKE 100 Query: 117 RAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYF----TFT 172 A +E+LN GKP +L +I +R++AG +H P G+Y + Sbjct: 101 ADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHA---PAAGEYLPGHTSMI 157 Query: 173 RHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFP 232 R +PIG+ G I PWN+PL+M AWK+APA+ GNTVV KP+EQTPL+AL + LI + P Sbjct: 158 RRDPIGIVGSIAPWNYPLMMMAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADI-LP 216 Query: 233 PGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSP 292 GV+N++ G G T G A+ +H + ++ TG GK + AA ++ +KR LELGGK+P Sbjct: 217 EGVVNVITGRGETVGNALINHPKVGMVSITGDIATGKKVLAAAAKT-VKRTHLELGGKAP 275 Query: 293 NIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSP 352 I++ DADL+ V ++N GQ CTA RI+ E IYE+ V Sbjct: 276 VIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLD 335 Query: 353 FDPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLGRKGFFIEPTVFSNVTDDM 411 D E GP I ++Q +++ ++ + ++ GG+ +GFF +PTV + T + Sbjct: 336 DDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQED 395 Query: 412 RIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWI 471 I + E+FGPV + RF D+ + AN+SD+GL ++V+T DI+KA+ +S +Q G WI Sbjct: 396 EIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKAMRAASRLQYGCTWI 455 Query: 472 NCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 N + L + P GG K SG G++M + L +Y+ V+ + + Sbjct: 456 NTHFMLTNEMPHGGIKQSGYGKDMSVYALEDYTAVRHIMIN 496 >4YWE-A nrPDB Length = 487 Score = 317 bits (811), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 186/482 (38%), Positives = 268/482 (55%), Gaps = 9/482 (1%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 ++ K FI EW PV +P+ G+ + DI++AV AAR AF+ W Sbjct: 9 MEEAKHFIAGEWTLPAQLETIPVVDPSDGQPFATIARGTAPDIERAVAAARDAFA--GPW 66 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 A+ERGR+L +L+ V LA +E+ + GKP QA + + F +YAG A Sbjct: 67 GAASAAERGRVLMRLSARVTDSIEELAAIEARDTGKPLKQARADAAA-LARYFEFYAGAA 125 Query: 155 DKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 DK+HG T+P Y T EP GV G I+PWN+P+ +F + AL GN V+KPAE Sbjct: 126 DKLHGETLPYQAGYTVLTVREPHGVTGHIVPWNYPMQIFGRSVGAALAAGNACVVKPAED 185 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 LS L + L EAG P G +NI+ GYG AGAA+A H GID I+FTGS GKL+ + Sbjct: 186 ACLSVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGIDHISFTGSPATGKLVTQM 245 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 A +++ VTLELGGKSP I+FADADLD A+ + N GQ C+AGSR+ +E ++YE Sbjct: 246 AAENHVP-VTLELGGKSPQIVFADADLDAALPVLVSAIVQNGGQTCSAGSRVLIERAVYE 304 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG- 393 V R VG P + GP I+ KQ ++ + + +G + G+ + Sbjct: 305 PLVERLATAFNGLRVG-PSRADLDCGPLINAKQQQRVWDFLSDAQHDGIPMAAHGQVVAD 363 Query: 394 --RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 GF+ P + +V R+A+EE+FGPV +RF DE + AN + +GLVA ++T Sbjct: 364 APESGFYQAPALLRDVPPSHRLAQEEVFGPVLAAMRFVDEDEAVALANGTPYGLVAGIWT 423 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNA-QSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 D + + ++ ++AG V+IN Y A + PFGG SG+GRE G L ++ +KT+ Sbjct: 424 RDGARQMRLARRLRAGQVFINNYGAGGGVELPFGGVGHSGHGREKGFEALYGFTALKTIA 483 Query: 511 VK 512 ++ Sbjct: 484 IR 485 >1WNB-A nrPDB Length = 495 Score = 315 bits (807), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 177/479 (36%), Positives = 272/479 (56%), Gaps = 14/479 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K+ IN E + E G PVYNPATG+ + E+ EA ++ A R A + + W + Sbjct: 25 KLLINGELVSGE-GEKQPVYNPATGDVLLEIAEASA---EQVDAAVRAADAAFAEWGQTT 80 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 R L KLAD++E + V A +ES N GKP AF ++ ++ FR++AG A ++ Sbjct: 81 PKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLN 140 Query: 159 GMTIPVDGDYF----TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 G+ G+Y + R +P+GV I PWN+PL+M AWK+APAL GN VV+KP+E Sbjct: 141 GLAA---GEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEI 197 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 TPL+AL + L K+ FP GV+NIL G G T G + H + ++ TGS G+ I Sbjct: 198 TPLTALKLAELAKDI-FPAGVVNILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISH 256 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 S++KR +ELGGK+P I+F DAD++ VE ++N GQ CTA RI+ ++ IY+ Sbjct: 257 TA-SSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYD 315 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLG 393 V + G+P D +TE GP ++ + ++ A G K+ GG+ Sbjct: 316 TLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVGKAVEEAKATGHIKVITGGEKRK 375 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 G++ PT+ + D I ++E+FGPV + F ++V+ AN+S +GL ++V+T D Sbjct: 376 GNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKD 435 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + +A VS+ +Q G W+N + L ++ P GG K+SG G++M +GL +Y+ V+ V VK Sbjct: 436 VGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVK 494 >3U4J-A nrPDB Length = 528 Score = 315 bits (807), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 204/505 (40%), Positives = 289/505 (57%), Gaps = 18/505 (3%) Query: 19 LMASLHLLP-SPTPNLEIKYT-KIFINNEWQNSESGRVFPVYNPA-TGEQVCEVQEADKA 75 +M S + P S P L IK ++ ++ + ++ SG +P GE V EA Sbjct: 2 VMLSNFIAPDSNDPRLRIKSRYQMLVDGKSVDAASGSTIDRVSPGHAGEVVGTWPEASAD 61 Query: 76 DIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQA 135 D+ KAV AAR AF G W RM +ER RL+ K+ADL+ + LA +ESL GKP QA Sbjct: 62 DVRKAVAAARKAFDAGP-WPRMSGAERSRLMFKVADLILARQEELALIESLEVGKPIAQA 120 Query: 136 -----FYVDLQGVIKTFRYYAGWADKIHGMTIP-VDGDYFTFTRHEPIGVCGQIIPWNFP 189 F DL + Y AG A + G T + D EP+GV G I PWNFP Sbjct: 121 RGEIGFCADL------WSYAAGQARALEGQTHNNIGDDRLGLVLREPVGVVGIITPWNFP 174 Query: 190 LLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAA 249 ++ + ++ A+ G TVV+KP+E T +++ + L +EAG P GV N++ GYG AG Sbjct: 175 FIIASERVPWAIGSGCTVVLKPSEFTSGTSIRLAELAREAGIPDGVFNVVTGYGDPAGQV 234 Query: 250 IASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAH 309 +A +D +AFTGS VG + E A R+ +KRV LELGGK P I+FADADLD A + Sbjct: 235 LAEDPNVDMVAFTGSVRVGTKLGEIAART-VKRVGLELGGKGPQIVFADADLDAAADGIA 293 Query: 310 QGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYN 369 GV+ N GQCC +GSR+ V+E I + + R ++ +++ G P + T+ G I + Sbjct: 294 YGVYHNAGQCCISGSRLLVQEGIRDALMERLLDISRKVAFGDPLNERTKIGAMISEAHAE 353 Query: 370 KILELIQSGVAEGAKLECGGKGLGRK-GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRF 428 K+ + +G+ GA+L GG+ +GR+ G + PTVF+ VT DM IA+EEIFGPV L F Sbjct: 354 KVHSYVTAGITSGAELLLGGERIGREAGLYYAPTVFAGVTPDMSIAREEIFGPVLSTLTF 413 Query: 429 KTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKM 488 KT DE + AN ++FGL A+V++ ++ AL ++AG WIN + P GG+K Sbjct: 414 KTADEAVALANATEFGLSASVWSTNLETALQTIRRIRAGRCWINSVIDGTPELPIGGYKK 473 Query: 489 SGNGREMGEFGLREYSEVKTVTVKI 513 SG GRE+G +G EYS+ K V V + Sbjct: 474 SGLGRELGRYGFDEYSQFKGVHVTL 498 >6MVR-A nrPDB Length = 767 Score = 311 bits (797), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 184/470 (39%), Positives = 273/470 (58%), Gaps = 24/470 (5%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 FI W + G +F NPATG+ + +V +A +AD+D AV+AAR A W + D + Sbjct: 36 FIGGAW--TAPGDLFATVNPATGQTLAQVSQATQADVDAAVKAARKA---QPAWAK-DGA 89 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 R R+L LA L+++ + A +E+L+ GKP +A +D+ + F ++AG+A ++ G Sbjct: 90 ARARVLYALARLLQKHARLFAVLETLDNGKPIREARDIDVPLAQRHFYHHAGYA-QLMGT 148 Query: 161 TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSAL 220 +P P+GVCGQ+IPWNFPLLM AWKIAPAL GNTVV+KPAE TPL+AL Sbjct: 149 EMP---------DRAPLGVCGQVIPWNFPLLMLAWKIAPALAMGNTVVLKPAEWTPLTAL 199 Query: 221 YMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNL 280 + +AG P GV+NI+ G G + + +DK+AFTGST VG+ I+EA + Sbjct: 200 LFADICGQAGVPAGVVNIVTGDGAVGEMIVTAQ--VDKVAFTGSTAVGRRIREATAGTG- 256 Query: 281 KRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRS 340 K ++LELGGK P ++ DAD+D AVE ++FNQGQ C AGSR+ V+E I + F + Sbjct: 257 KALSLELGGKGPYVVCDDADIDSAVEGLVDAIWFNQGQVCCAGSRLLVQEGIADVFHAKL 316 Query: 341 VERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIE 400 R +G P D + G + Q ++ +++ + +G + G + Sbjct: 317 RARMDSLRIGDPLDKCIDIGAMVHPDQLARVRDMVAANT-DGEVYQTAVPA----GCYYP 371 Query: 401 PTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTV 460 PT+ S + + ++EIFGPV F+T E +E ANN+ +GL A+V++ ++N AL + Sbjct: 372 PTLISGLAPASPLMQQEIFGPVLVSTTFRTPAEAVEIANNTAYGLAASVWSENVNLALDL 431 Query: 461 SSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 + + AG VWIN N ++A +PFGG + SG GRE G GL Y+ T Sbjct: 432 APKLVAGIVWINGTNMMDAAAPFGGVRESGFGREGGWEGLAGYTRPAIAT 481 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 68/253 (26%), Positives = 108/253 (42%), Gaps = 24/253 (9%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 + K++I + + G VY P G+ + +++ D+ AV+A A S W Sbjct: 501 RTAKLYIGGKQTRPDGGYSRAVYGP-KGKLLGHASLSNRKDLRNAVEAMNAA----SGWS 555 Query: 96 RMDASERGRLLDKLAD-LVERDRAVLATMESLNG--GKPFLQAFYVDLQGVIKTFRYYAG 152 R R ++L + + L R ++ + G GK ++ I A Sbjct: 556 RTTGHLRAQILYFIGENLSARADEFANRIKDMTGKDGK-------AEVAASIDRLFSAAA 608 Query: 153 WADKIHGMT--IPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 WADK G +P+ G EP+G G + P PLL +APA+ GN V + Sbjct: 609 WADKYDGQVKGVPLRG--VALAMKEPVGKIGILCPDAAPLLGLVSLMAPAIAMGNRVTLA 666 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKI-AFTGSTEVGK 269 +E PL+A ++ + P GV+NIL G +A H+ +D + +G +V Sbjct: 667 ASEAFPLAATDFYQVLDTSDVPAGVVNILTGAHADLAEPMARHLDLDAVWGLSGHAQV-- 724 Query: 270 LIQEAAGRSNLKR 282 EAA NLKR Sbjct: 725 --IEAASAGNLKR 735 >3JZ4-A nrPDB Length = 481 Score = 311 bits (797), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 171/474 (36%), Positives = 261/474 (55%), Gaps = 6/474 (1%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 IN EW ++ +G V NPA G+++ V + + A+ AA A WR + A Sbjct: 13 LINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRALP---AWRALTAK 69 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 ER +L +L+ + LA + +L GKP +A ++ ++A +I+G Sbjct: 70 ERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEA-KGEISYAASFIEWFAEEGKRIYGD 128 Query: 161 TIP-VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 TIP D +PIGV I PWNFP M K PAL G T+V+KPA QTP SA Sbjct: 129 TIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSA 188 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 L + L AG P GV N++ G G + S+ + K++FTGSTE+G+ + E + + Sbjct: 189 LALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAK-D 247 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 +K+V+LELGG +P I+F DADLD AVE A F N GQ C +R++V++ +Y+ F + Sbjct: 248 IKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEK 307 Query: 340 SVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFI 399 + + +G D GP ID+K K+ E I + +GA++ CGGK R G F Sbjct: 308 LQQAMSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFF 367 Query: 400 EPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALT 459 +PT+ +V + +++KEE FGP+ + RFK +VI +AN+++FGL A + D+++ Sbjct: 368 QPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFR 427 Query: 460 VSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 V A++ G V IN N +PFGG K SG GRE ++G+ +Y E+K + + + Sbjct: 428 VGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCIGL 481 >3I44-A nrPDB Length = 497 Score = 306 bits (783), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 170/483 (35%), Positives = 270/483 (55%), Gaps = 9/483 (1%) Query: 31 PNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL 90 P + K +IN W + + V +P+T E + D DKA+ AA+ AF Sbjct: 19 PGSMLNKRKFYINGLWDDPSTPHDLYVIDPSTEEACAVISLGSTRDADKAINAAKKAFQ- 77 Query: 91 GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYY 150 W+ ER ++K+ ++ E+ + +A S+ G P A R + Sbjct: 78 --TWKTTSPHERLGFVEKILEIYEKRSSDMAKTISMEMGAPIDMALNAQTATGSSHIRNF 135 Query: 151 AGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 + ++G+ ++ IGV G I PWN+P+ K+ PAL G T+V+K Sbjct: 136 IKAYKEFSFQEALIEGNEQAILHYDAIGVVGLITPWNWPMNQVTLKVIPALLAGCTMVLK 195 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 P+E PLSA+ ++ EA P GV N++ G G G+ +++H ++ I+FTGST GK Sbjct: 196 PSEIAPLSAMLFAEILDEAALPSGVFNLINGDGANVGSYLSAHPDLEMISFTGSTRAGKD 255 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 I + A + LKRV LELGGK NIIFADAD+D A+++ + F+N GQ C A +R+ VE+ Sbjct: 256 ISKNASNT-LKRVCLELGGKGANIIFADADID-ALQRGVRHCFYNSGQSCNAPTRMLVEQ 313 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 +IY++ ++ + + A++ VG GP + K+QY+KI +LIQSG+ EGA L GG Sbjct: 314 AIYDKAIKTAKDIAEKTQVGPGHQTGNHIGPVVSKEQYDKIQDLIQSGIDEGATLVTGGT 373 Query: 391 GLG---RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVA 447 GL +G+++ PTVF++V MRI +EEIFGPV +L F T DE + AN++++GL Sbjct: 374 GLPMGMERGYYVRPTVFADVKPHMRIFREEIFGPVLSLLPFNTEDEAVTLANDTEYGLTN 433 Query: 448 AVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVK 507 + + D +K +++ +++G V +N + L S FGG K SG RE G +G++E+ + K Sbjct: 434 YIQSQDRSKCRRIAAQVRSGMVEVNGHE-LPGGSYFGGVKFSGRAREGGLWGIKEFLDTK 492 Query: 508 TVT 510 ++ Sbjct: 493 AIS 495 >6C43-A nrPDB Length = 477 Score = 306 bits (783), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 179/479 (37%), Positives = 266/479 (55%), Gaps = 14/479 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 ++ IN + E R VYNPATGE + E+ EA A +D AVQAA AF+ W + Sbjct: 7 QLLINGVLVDGEGERQ-SVYNPATGEVILEIAEASPAQVDAAVQAADNAFA---EWGQTT 62 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 R L KLAD +E++ A +ES N GKP ++ ++ FR++AG A + Sbjct: 63 PKARAECLLKLADSIEQNALEFARLESQNCGKPLHCVINDEIPAIVDVFRFFAGAARCLS 122 Query: 159 GMTIPVDGDYF----TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 G+ G+Y + R +PIGV I PWN+PL+M AWK+APAL GN VVIKP+E Sbjct: 123 GLAA---GEYLEGHTSMIRRDPIGVVASIAPWNYPLMMAAWKLAPALAAGNCVVIKPSEI 179 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 TPL+AL + L K+ FPPGV+N+L G G T G + H + ++ TGS G+ I Sbjct: 180 TPLTALKLAVLAKDI-FPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGEHILRH 238 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 + +KR +ELGGK+P I+F DADLD + F+N GQ CTA RI+ + IY+ Sbjct: 239 TAPA-IKRTHMELGGKAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAACRIYAQRGIYD 297 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA-EGAKLECGGKGLG 393 V + +G+P D +TE GP ++ ++ A ++ GG Sbjct: 298 ALVEKLGNAVSSLKMGAPEDESTELGPLSSLAHLKRVTAAVEEAKALSHIRVITGGSQTE 357 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 KG++ PT+ ++ + I + E+FGPV I F D+V+ AN+S +GL ++V+T D Sbjct: 358 GKGYYFAPTLLADAKQEDAIVQREVFGPVVSITVFDDEDQVLRWANDSRYGLASSVWTQD 417 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + +A +S+ +Q G WIN + L ++ P GG K SG G++M +GL +Y+ V+ + VK Sbjct: 418 VGRAHRLSARLQYGCTWINTHFMLVSEMPHGGQKQSGYGKDMSLYGLEDYTLVRHIMVK 476 >4U3W-A nrPDB Length = 505 Score = 305 bits (780), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 187/485 (38%), Positives = 265/485 (54%), Gaps = 15/485 (3%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + +IN E+ SG FP +P G ++ +V EAD A +D AVQAA A G WR Sbjct: 25 RHYINGEF--VASGTTFPNLSPVDGRKLADVCEADAALVDSAVQAAHAAQKAG--WRDTT 80 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ++R L K+AD +E E + G+P QA +D+ I FR +A Sbjct: 81 PAQRAAWLHKIADGIEARFDEFVAAEVADTGRPVAQARTLDIARGIANFRTFADLVRTAS 140 Query: 159 GM---TIPVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 G T DG + + +P+GV G I PWN PLL+F WK+APAL GN VV KP+E+ Sbjct: 141 GEYFETHAADGSELINYVTRKPLGVIGIISPWNLPLLLFTWKVAPALAMGNCVVAKPSEE 200 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTA-GAAIASHIGIDKIAFTGSTEVGKLIQE 273 TP SA + ++ + G PPGV N++ G+G A G + H I I FTG + G I + Sbjct: 201 TPSSATLLAEVMHDVGLPPGVFNLIHGHGQNAAGEFLTRHPDISAITFTGESRTGSTIMK 260 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 A +K V+ ELGGK+ ++FADAD D AV + F N GQ C R++VE I+ Sbjct: 261 AVA-DGVKEVSFELGGKNAAVVFADADFDAAVAGVLRSSFTNAGQVCLCSERVYVERPIF 319 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK--- 390 E FV E+A+ VG+P DP T GP I + +K+L + V EGA + GG Sbjct: 320 ERFVAALKEQAQALRVGAPEDPATTMGPLISRGHRDKVLSYFRLAVEEGATVVTGGGAPS 379 Query: 391 -GLGRK-GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 G R G F+ PT+++ + D R +EEIFGPV I F EV++R N+S +GL A+ Sbjct: 380 FGDARDDGAFVMPTIWTGLPDSARCVREEIFGPVCHIAPFDDEAEVVKRVNDSAYGLAAS 439 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 ++T + + V+ ++ G VW+N + + ++PFGG K+SG GRE G L YSE+ Sbjct: 440 IWTTQLARGHRVAKQIETGIVWVNAWFVRDLRTPFGGTKLSGLGREGGRHSLDFYSELTN 499 Query: 509 VTVKI 513 V V+I Sbjct: 500 VCVRI 504 >4V6H-A nrPDB Length = 484 Score = 300 bits (767), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 178/474 (37%), Positives = 262/474 (55%), Gaps = 6/474 (1%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 +I EWQ ++S F V++PATGE + V + A+ +A++AA+ A++ WR A Sbjct: 16 YIGGEWQAADSDATFEVFDPATGESLGTVPKMGAAETARAIEAAQAAWA---GWRMKTAK 72 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 ER +L + DLV + LA + + GKP +A ++ ++A ++ G Sbjct: 73 ERAAILRRWFDLVIANSDDLALILTTEQGKPLAEA-KGEIAYAASFIEWFAEEGKRVAGD 131 Query: 161 TIPV-DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 T+P D + EPIGVC I PWNFP M A K+ PAL G +V+KPAE TP SA Sbjct: 132 TLPTPDANKRIVVVKEPIGVCAAITPWNFPAAMIARKVGPALAAGCPIVVKPAESTPFSA 191 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 L M L + AG P GV++++ G G I S+ + K++FTGST VG+L+ A Sbjct: 192 LAMAFLAERAGVPKGVLSVVIGDPKAIGTEITSNPIVRKLSFTGSTAVGRLLM-AQSAPT 250 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 +K++TLELGG +P I+F DADLD AVE A + N GQ C +R FV E +Y+ F + Sbjct: 251 VKKLTLELGGNAPFIVFDDADLDAAVEGAIASKYRNNGQTCVCTNRFFVHERVYDAFADK 310 Query: 340 SVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFI 399 + VG + GP I++ K+ I +A+GA L GGK F Sbjct: 311 LAAAVSKLKVGRGTESGATLGPLINEAAVKKVESHIADALAKGASLMTGGKRHALGHGFF 370 Query: 400 EPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALT 459 EPTV + V DM +AKEE FGP+ + RF + +E++ AN+++FGL A +++ DI + Sbjct: 371 EPTVLTGVKPDMDVAKEETFGPLAPLFRFASEEELVRLANDTEFGLAAYLYSRDIGRVWR 430 Query: 460 VSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513 V+ A++ G V IN N +PFGG K SG GRE +G+ +Y +K + V + Sbjct: 431 VAEALEYGMVGINTGLISNEVAPFGGVKQSGLGREGSHYGIDDYVVIKYLCVAV 484 >3EK1-A nrPDB Length = 504 Score = 299 bits (765), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 182/474 (38%), Positives = 268/474 (56%), Gaps = 10/474 (2%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 ++ +N W ++ G V NPA G + V A I +A+ A+ A S W Sbjct: 33 SQCLVNGRWIDAADGTTIKVTNPADGSVIGTVPSLSVATIKEAIDASAKALS---GWAAK 89 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 A ER +L K DL+ + +A + + GKP +A L ++A A ++ Sbjct: 90 TAKERAGILRKWFDLIIANADDIALIMTSEQGKPLAEARGEVLYAA-SFIEWFAEEAKRV 148 Query: 158 HGMTIPV--DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 +G TIP +G T R +P+GV I PWNFP M K APAL G T++++PA+ T Sbjct: 149 YGDTIPAPQNGQRLTVIR-QPVGVTAAITPWNFPAAMITRKAAPALAAGCTMIVRPADLT 207 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 PL+AL +G L ++AG P GV+ I+ G GA + S+ + K++FTGSTEVG+L+ A Sbjct: 208 PLTALALGVLAEKAGIPAGVLQIVTGKAREIGAELTSNDTVRKLSFTGSTEVGRLLM-AQ 266 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEE 335 +KR++LELGG +P I+F DADLD AV+ A + N GQ C +RI+V+ +Y++ Sbjct: 267 CAPTIKRISLELGGNAPFIVFDDADLDAAVDGAMVSKYRNAGQTCVCANRIYVQRGVYDK 326 Query: 336 FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 F + + K VG+ +P GP I++K K+ I+ V++GAKL GGK LG Sbjct: 327 FAEKLAAKVKELKVGNGTEPGVVIGPMIEEKAITKVKAHIEDAVSKGAKLITGGKELG-- 384 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 G F EP + + VT DM +AKEE FGP+ + F T +EVI +AN++ FGL A +T + + Sbjct: 385 GLFFEPGILTGVTSDMLVAKEETFGPLAPLFAFDTEEEVIAQANDTIFGLAAYFYTENFS 444 Query: 456 KALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 +A+ VS A++ G V N N +PFGG K SG GRE ++G+ EY E K + Sbjct: 445 RAIRVSEALEYGMVGHNTGLISNEVAPFGGVKQSGLGREGSKYGIEEYLETKYI 498 >5J77-A nrPDB Length = 508 Score = 298 bits (763), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 164/485 (33%), Positives = 269/485 (55%), Gaps = 13/485 (2%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 TK++I+ +W NS SG+ Y+P TG+ + ++ A + D+D+A+ AA AF W + Sbjct: 3 TKLYIDGQWVNSSSGKTVDKYSPVTGQVIGRMEAATRDDVDRAIDAAEDAFW---AWNDL 59 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 + ER +++ + +L+E++RA L + GKP +A ++ GVI +YYA WA K+ Sbjct: 60 GSVERSKIIYRAKELIEKNRAELENIIMEENGKPVKEA-KEEVDGVIDQIQYYAEWARKL 118 Query: 158 HGMTIPVDGDYFTFTRHE-PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTP 216 +G + + +++ P G+ + PWNFP M A K+APAL GNTVV+KP+ TP Sbjct: 119 NGEVVEGTSSHRKIFQYKVPYGIVVALTPWNFPAGMVARKLAPALLTGNTVVLKPSSDTP 178 Query: 217 LSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAG 276 SA ++ EAG P GV+N + G G G I H ++ I TGST G+ I + A Sbjct: 179 GSAEWIVRKFVEAGVPKGVLNFITGRGSEIGDYIVEHKKVNLITMTGSTATGQRIMQKAS 238 Query: 277 RSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEF 336 +N+ ++ LELGGK+P +++ DAD+D A++ ++N GQ C A R++V E IY+ F Sbjct: 239 -ANMAKLILELGGKAPFMVWKDADMDNALKTLLWAKYWNAGQSCIAAERLYVHEDIYDTF 297 Query: 337 VRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG-----KG 391 + R VE +++ +G P + GP I+K E+++ GAK+ GG G Sbjct: 298 MSRFVELSRKLALGDP--KNADMGPLINKGALQATSEIVEEAKESGAKILFGGSQPSLSG 355 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 R G+F PT+ N +I +EEIF PV + +++E+ + AN++ +GL + +FT Sbjct: 356 PYRNGYFFLPTIIGNADQKSKIFQEEIFAPVIGARKISSVEEMYDLANDNKYGLASYLFT 415 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 D N S ++ G +++N +Q GF+M+G E ++G+ EY ++K + V Sbjct: 416 KDPNIIFEASERIRFGELYVNMPGPEASQGYHTGFRMTGQAGEGSKYGISEYLKLKNIYV 475 Query: 512 KIPQK 516 K Sbjct: 476 DYSGK 480 >3TY7-A nrPDB Length = 478 Score = 296 bits (758), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 180/479 (37%), Positives = 259/479 (54%), Gaps = 18/479 (3%) Query: 37 YTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRR 96 YTK +IN EW S S V NPAT E + +V + +KAD+DKAV+AA + +R Sbjct: 7 YTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADDVYLE---FRH 63 Query: 97 MDASERGRLLDKLADLVE--RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 ER LLDK+ E +D V A + L G P + V Q ++ Sbjct: 64 TSVKERQALLDKIVKEYENRKDDIVQAITDEL--GAPLSLSERVHYQ---MGLNHFVAAR 118 Query: 155 DKIHGMTIP-VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 D + GD E IGV G I PWNFP + K+A A G+ VV+KP+E Sbjct: 119 DALDNYEFEERRGD--DLVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSE 176 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 +TP +A+ + + + G P GV N++ G G G ++ H + ++FTGS G I E Sbjct: 177 ETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIME 236 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 A + + K+V+LELGGKSP I+ D D+ A + V N GQ CTAG+R+ V I Sbjct: 237 KAAK-DFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNKIK 295 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 + F+ E+ + VG+P + T+ GP I KKQ++++ I G+ EGA+L GG G Sbjct: 296 DAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPGKP 355 Query: 394 ---RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 KG+F PT+F NV + M IA+EEIFGPV ++ + +DE I+ AN++ +GL V Sbjct: 356 EGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGYVI 415 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 D V+ +++AGTV IN PFGG+K SG GRE G++G+ E+ EVK++ Sbjct: 416 GKDKETLHKVARSIEAGTVEINEA-GRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSI 473 >4JZ6-A nrPDB Length = 500 Score = 292 bits (748), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 184/481 (38%), Positives = 262/481 (54%), Gaps = 14/481 (2%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 TK+FINN W +S + F +P + E + E A D KA QAA AF W+ + Sbjct: 20 TKLFINNAWIDSSDQQTFERKHPVSSEVMTESANATVTDAIKAAQAAEEAFK---TWKDV 76 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 SER RLL K+AD++E + ++ G L A + ++ FR A A +I Sbjct: 77 GPSERRRLLLKVADVMESKTPKFIEVMAMEVGASALWAGF-NVHASANVFREAASLATQI 135 Query: 158 HGMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTP 216 G TIP D + + T +P+G I+PWN ++ A IA L CGNTVV K +E +P Sbjct: 136 QGETIPTDKAETLSMTLRQPVGPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSEFSP 195 Query: 217 LSALYMGALIKEAGFPPGVINIL---PGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 + + ++EAG P GV+N L P P A+ S I +I FTGST VG +I + Sbjct: 196 ATHALITQCVQEAGLPAGVLNYLNSSPDRSPEIADALISAKEIRRINFTGSTRVGSIIAQ 255 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 A + +LKR LELGGKSP I+ DAD++ AV+ A G F QGQ C + R+ V+E I Sbjct: 256 KAAQ-HLKRCLLELGGKSPLIVLDDADINAAVKAAVFGSFLFQGQICMSTERLVVDEKIA 314 Query: 334 EEFVRRSVERAKRRVVGSP-FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL 392 +EFV R VE+ +R VG P GP + +I L + + +GAK+ CGG Sbjct: 315 DEFVARFVEKTERLSVGDPCLTGDCIIGPMVSPNSGERINGLFKDAIDKGAKVVCGGMA- 373 Query: 393 GRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452 +G + T+ +V DMRI EE FGP+ ++R K E I AN+S +GL + VF Sbjct: 374 --QGAVMPATILDHVKSDMRIYDEETFGPITVVIRCKGEAEAIRIANDSVYGLSSGVFGR 431 Query: 453 DINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 DIN+AL V +++ G V IN N AQ+P+GG K +G GR G + E++E+K +T+ Sbjct: 432 DINRALRVGMSIEYGCVHINGSTVQNEAQAPYGGTKNTGYGRFDGRAVIDEFTELKWLTI 491 Query: 512 K 512 + Sbjct: 492 E 492 >3B4W-A nrPDB Length = 495 Score = 285 bits (730), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 187/482 (38%), Positives = 262/482 (54%), Gaps = 10/482 (2%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 +Y K+FI +W + V V PATGE V +V A AD+D AV AAR AF G W Sbjct: 7 EYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAADVDAAVAAARAAFDNGP-WP 65 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 ER ++ ++ + + + + G+P + G + Y+AG AD Sbjct: 66 STPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPPTIIETMHWMGSMGAMNYFAGAAD 125 Query: 156 KIHGMTIPVDGDYF-TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 K+ T G Y + EP+GV G I+ WN PL + KIAPAL G T+V+KPA + Sbjct: 126 KVT-WTETRTGSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAE 184 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 TPL+A + + E G P GV++++PG G G A+ S+ ID FTGS+ VG+ + Sbjct: 185 TPLTANALAEVFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGRR 243 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 A LK TLELGGKS II D DL A+ N GQ C +RI S Y+ Sbjct: 244 AAEM-LKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQTRILAPRSRYD 302 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG---KG 391 E V VG P DP + GP I +KQ ++ I G+ EGA+L CGG +G Sbjct: 303 EIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGYIAKGIEEGARLVCGGGRPEG 362 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 L GFFI+PTVF++V + M IA+EEIFGPV I+ + T ++ I AN+S +GL +V+T Sbjct: 363 L-DNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWT 421 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 D+ K + +S ++ GT IN Y A + SPFGG+K SG GRE G G+ +++ K+V + Sbjct: 422 TDVPKGIKISQQIRTGTYGINWY-AFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLL 480 Query: 512 KI 513 + Sbjct: 481 PM 482 >3RHD-A nrPDB Length = 486 Score = 273 bits (698), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 167/477 (35%), Positives = 263/477 (55%), Gaps = 21/477 (4%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 +FI+ +W N E V NP + E + ++ + + +A+ A V + + Sbjct: 2 MFIDGKWINRED---MDVINPYSLEVIKKIPALSREEAKEAIDTAE---KYKEVMKNLPI 55 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 ++R +L +A ++ + LA + +++ GKP QA V+++ I TF+ A + + Sbjct: 56 TKRYNILMNIAKQIKEKKEELAKILAIDAGKPIKQA-RVEVERSIGTFKLAAFYVKEHRD 114 Query: 160 MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 IP D D FTR EP+G+ G I P+NFPL + A KIAPA+ GN +V P+ + PL Sbjct: 115 EVIPSD-DRLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVC 173 Query: 220 LYMGALIKEA----GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 + + +I+ A P GV N+L G G G I + ++ I+FTGS++VG+LI + A Sbjct: 174 IELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKA 233 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEE 335 G K++ LELGG +PNI+ DADL+ AV +G F GQ C + I V+ESI ++ Sbjct: 234 G---FKKIALELGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADK 290 Query: 336 FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 F+ V +AK VG+P D T+ GP I + + ++++ + EG KL GGK R Sbjct: 291 FIEMFVNKAKVLNVGNPLDEKTDVGPLISVEHAEWVEKVVEKAIDEGGKLLLGGK---RD 347 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 PT+ V D + K E F PV I+R +E+I+ AN++++GL +A+FTNDIN Sbjct: 348 KALFYPTILE-VDRDNILCKTETFAPVIPIIR-TNEEEMIDIANSTEYGLHSAIFTNDIN 405 Query: 456 KALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 K+L + ++ G V IN + + PFGG K SG GRE ++ + E S +KT+ + Sbjct: 406 KSLKFAENLEFGGVVINDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIII 462 >5UR2-A nrPDB Length = 984 Score = 270 bits (690), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 185/512 (36%), Positives = 274/512 (53%), Gaps = 28/512 (5%) Query: 12 VKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVC-EVQ 70 VKAD ++ +L + P I INN + +SG++F NP+ +Q+ ++Q Sbjct: 475 VKADREKMLKALAEAKASLP----VNVNIVINN--KELQSGKIFDRVNPSQSDQIVGKIQ 528 Query: 71 EADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGK 130 A ++A+QAA+ A+ W+ + +R L+DKLAD++ RDR L + L GK Sbjct: 529 MATTEQAEQAMQAAQTAYK---TWKNVPCEQRAALVDKLADIMTRDRFKLIATQVLEVGK 585 Query: 131 PFLQAFYVDLQGVIKTFRYYAGWADKIHGMT----IPVDGDYFTFTRHEPIGVCGQIIPW 186 P+ +A D+ I RYYA ++ +P + ++ + GV I PW Sbjct: 586 PWAEA-DGDIGEAIDFCRYYARHMRELQKPLRVGGLPGELSHYIYKSR---GVTAVIAPW 641 Query: 187 NFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTA 246 NFPL + A + A GNTVV+KPAEQ+ + A + +I+EAGFP GVIN LPGYG Sbjct: 642 NFPLAILAGMVTAAAVAGNTVVMKPAEQSTVVAWGLMKMIQEAGFPQGVINFLPGYGEEV 701 Query: 247 GAAIASHIGIDKIAFTGSTEVGKLIQEAA-----GRSNLKRVTLELGGKSPNIIFADADL 301 G I +H IAFTGS VG I A G+ ++KR +E+GGK+ II DADL Sbjct: 702 GEYIVNHKYTTTIAFTGSKAVGLHIMNRAAVVQPGQQHVKRCIIEMGGKNAVIIDNDADL 761 Query: 302 DYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGP 361 D AV+ F GQ C+A SR+ V + +Y+ FV R VE AK + +P GP Sbjct: 762 DEAVDGVIYSAFGFSGQKCSAASRVIVLDEVYDRFVDRLVETAKSIEIHPAENPKAYMGP 821 Query: 362 QIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGP 421 +DK+ Y++IL I + KL G G GFF PT+F +V D ++A+ EIFGP Sbjct: 822 VVDKEAYDRILGTIAEA-EKNHKLLFKGSVPG-GGFFAPPTIFGDVPGDAKLAQAEIFGP 879 Query: 422 VQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWIN--CYNALNA 479 V ++R K +D+ ++ AN++++ L VF+ V ++ G +++N A+ Sbjct: 880 VVAVIRAKNLDQALDIANSTEYALTGGVFSRSPANINRVKEELEVGNLYVNRGITGAMVD 939 Query: 480 QSPFGGFKMSGNGREM-GEFGLREYSEVKTVT 510 + PFGGFKMSG G + G L++Y E VT Sbjct: 940 RHPFGGFKMSGIGSKTGGPDYLKQYMEPACVT 971 >5EUY-A nrPDB Length = 491 Score = 267 bits (682), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 165/492 (33%), Positives = 258/492 (52%), Gaps = 25/492 (5%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 +L I +IN E++ +G +P G ++ EV + + D +A+ +A F Sbjct: 3 DLNIMKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSA---FEAL 59 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAF----YVD--LQGVIK 145 W + A R L K+ ++ + + + ++ GG + + + + + +Q + Sbjct: 60 KAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAE 119 Query: 146 TFRYYAGWADKIHG-MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCG 204 R+Y G + TI V F R + GV G I PWN+PL + KIA L G Sbjct: 120 LARHYQGRVLQSDSESTISV-----VFKRSK--GVVGVITPWNYPLSISMKKIAHTLAVG 172 Query: 205 NTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGS 264 NTVV KPA TP++ + ++ +AG P GV N++ G GP G I +H + + FTG Sbjct: 173 NTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGE 232 Query: 265 TEVGKLI-QEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAG 323 + G+ I +AAG LK VTLELGG P II D D+DYA A F+QGQ CT+ Sbjct: 233 SSTGREIAAKAAG--TLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSA 290 Query: 324 SRIFVEESIYEEFVRRSVERAKRRVVGSPF-DPTTEQGPQIDKKQYNKILELIQSGVAEG 382 RI V +++ ++F+ R V K + P D + GP I+++Q + E + V+ G Sbjct: 291 KRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRG 350 Query: 383 AKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSD 442 +L GG+ G F EP +F +V + RI +EE+FGPV+ I+ + D+ +E AN++D Sbjct: 351 GRLLIGGRSWGN---FFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTD 407 Query: 443 FGLVAAVFTNDINKALTVSSAMQAGTVWINCYNAL-NAQSPFGGFKMSGNGREMGEFGLR 501 +GL AV TN++N+A ++ A+++G IN L + PFGG K SG GRE GE+ Sbjct: 408 YGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFH 467 Query: 502 EYSEVKTVTVKI 513 E + + VTV + Sbjct: 468 ETTYDRWVTVTL 479 >6FK3-A nrPDB Length = 536 Score = 263 bits (672), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 180/469 (38%), Positives = 254/469 (54%), Gaps = 31/469 (6%) Query: 59 NPATGEQV-CEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDR 117 NP+ E V EADK + KA AR AF+ W R A RG++L L ++ER++ Sbjct: 39 NPSDREDVVARFPEADKDLVRKAALKAREAFA---EWSRTPAPIRGQVLFNLVKILEREK 95 Query: 118 AVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPV---DGDYFTFTRH 174 L + GK +A D+Q I T ++A +++G T+P D + FTF R Sbjct: 96 PTLTRLMVREVGKTPKEA-AGDVQEAIDTALFFASEGRRLYGQTVPSEMRDKELFTFRR- 153 Query: 175 EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPG 234 P+GV G I NFP+ + +WK+ PA+ GNTVV KP+E P + L +EAG PPG Sbjct: 154 -PLGVVGIITAGNFPIAVPSWKLIPAVLTGNTVVWKPSEDAPTLSFVFAKLFEEAGLPPG 212 Query: 235 VINILPGYGP-TAGAAIASHIG---IDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 290 V+N++ G G + G + + K AFTGST+VG+ I E AGR NL R TLELGGK Sbjct: 213 VLNVVFGGGKGSTGQWMVELMDEGLFQKFAFTGSTQVGRWIGEVAGR-NLIRPTLELGGK 271 Query: 291 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG 350 +P ++ DADLD AVE A F GQ CT+ I V+ IYEEF RR +ER + +VG Sbjct: 272 NPLVVMRDADLDLAVEGAWWSAFATGGQRCTSAGNILVDAPIYEEFKRRFLERVEATLVG 331 Query: 351 SP-FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK------------GF 397 +P P GP I+++ + + E + G AEGA+L G + R+ G Sbjct: 332 NPLLHPEVTYGPFINERFFARWQEHYRVGEAEGARLLFGRGRITRENPYPRFLGDPEAGL 391 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457 + PTV+ V R+ EE+FGP +++ ++E I AN++ +GL +A++TN + A Sbjct: 392 YGWPTVW-EVRPGTRLFTEEVFGPTINLVKVDGIEEAIAVANSTPYGLSSAIYTNHRHWA 450 Query: 458 LTVSSAMQAGTVWINCYN-ALNAQSPFGGFKMSGN-GREMGEFGLREYS 504 ++AG IN A PFGG K SGN GRE G + L EY+ Sbjct: 451 YLFKVGIRAGMTSINNATVGAEAHLPFGGVKASGNGGRESGIWVLEEYT 499 >3RJL-A nrPDB Length = 538 Score = 259 bits (663), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 165/479 (34%), Positives = 240/479 (50%), Gaps = 33/479 (6%) Query: 42 INNEW-----------QNSESGRVFPVYNPATGEQVC-EVQEADKADIDKAVQAARLAFS 89 +NNEW + E+ NPA E+V V +A + +KA+QAA AF Sbjct: 29 VNNEWLGQSYPLVIDGERYETENKIVSINPANKEEVVGTVSKATQDHAEKAIQAAAKAFE 88 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 WR D ER +L + V R + + + GKP+ +A D I Y Sbjct: 89 ---TWRYTDPEERAAVLFRAVAKVRRKKHEFSALLVKEAGKPWNEA-DADTAEAIDFMEY 144 Query: 150 YAGWADKIHGMTIPVDG-----DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCG 204 YA ++ PV+ + + +T P GV I PWNF + A + G Sbjct: 145 YARQMIEL-AKGKPVNSREGERNQYVYT---PTGVTVVIPPWNFLFAIMAGTTVAPIVTG 200 Query: 205 NTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGS 264 NTVV+KPA P+ A +++E+G P GV+N +PG G G + H I FTGS Sbjct: 201 NTVVLKPASAAPVIAAKFVEVLEESGLPKGVVNFVPGSGAEVGDYLVDHPKTSIITFTGS 260 Query: 265 TEVGKLIQEAA-----GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQC 319 EVG I E A G+++LK+V E+GGK ++ D D++ A + F GQ Sbjct: 261 REVGTRIFERAAKVQPGQTHLKQVIAEMGGKDTVVVDEDCDIELAAQSIFTSAFGFAGQK 320 Query: 320 CTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGV 379 C+AGSR V E +Y+E ++R +E + + VG P GP ID+ +NKI++ I+ G Sbjct: 321 CSAGSRAVVHEKVYDEVLKRVIEITESKKVGEPDSADVYMGPVIDQASFNKIMDYIEIGK 380 Query: 380 AEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERAN 439 EG +L GGKG KG+FIEPT+F+++ R+ +EEIFGPV + + DE +E AN Sbjct: 381 EEG-RLVSGGKGDDSKGYFIEPTIFADLDPKARLMQEEIFGPVVAFSKVSSFDEALEVAN 439 Query: 440 NSDFGLVAAVFTNDINKALTVSSAMQAGTVWI--NCYNALNAQSPFGGFKMSGNGREMG 496 N+++GL AV T + + G ++ NC A+ PFGGFKMSG + G Sbjct: 440 NTEYGLTGAVITKNRDHINRAKQEFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAG 498 >3QAN-A nrPDB Length = 538 Score = 258 bits (658), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 166/470 (35%), Positives = 248/470 (52%), Gaps = 24/470 (5%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQ-VCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + IN E +E +NPA +Q V V +A++ +KA+Q+A AF WR ++ Sbjct: 40 LIINGERVTTEDK--IQSWNPARKDQLVGSVSKANQDLAEKAIQSADEAFQ---TWRNVN 94 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ER +L K A ++ R + + GKP+ +A D I YYA +++ Sbjct: 95 PEERANILVKAAAIIRRRKHEFSAWLVHEAGKPWKEA-DADTAEAIDFLEYYARQMIELN 153 Query: 159 G----MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPL-LMFAWKIAPALCCGNTVVIKPAE 213 ++ P + + + +T P+GV I PWNF L +M +AP + GNTVV+KPA Sbjct: 154 RGKEILSRPGEQNRYFYT---PMGVTVTISPWNFALAIMVGTAVAP-IVTGNTVVLKPAS 209 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-KLIQ 272 TP+ A ++++AG P GVIN +PG G G + H I FTGS +VG +L + Sbjct: 210 TTPVVAAKFVEVLEDAGLPKGVINYVPGSGAEVGDYLVDHPKTSLITFTGSKDVGVRLYE 269 Query: 273 EAA----GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 AA G+++LKRV +E+GGK ++ DADLD A E F GQ C+AGSR + Sbjct: 270 RAAVVRPGQNHLKRVIVEMGGKDTVVVDRDADLDLAAESILVSAFGFSGQKCSAGSRAVI 329 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 + +Y+E + ++V AK VG P + GP ID+K + KI+ I+ G EG +L G Sbjct: 330 HKDVYDEVLEKTVALAKNLTVGDPTNRDNYMGPVIDEKAFEKIMSYIEIGKKEG-RLMTG 388 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 G+G GFFI+PT+ +++ + I +EEIFGPV + D +E ANN+++GL A Sbjct: 389 GEGDSSTGFFIQPTIIADLDPEAVIMQEEIFGPVVAFSKANDFDHALEIANNTEYGLTGA 448 Query: 449 VFTNDINKALTVSSAMQAGTVWI--NCYNALNAQSPFGGFKMSGNGREMG 496 V T + G ++ NC A+ PFGGFKMSG + G Sbjct: 449 VITRNRAHIEQAKREFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAG 498 >2HG2-A nrPDB Length = 479 Score = 256 bits (654), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 154/477 (32%), Positives = 246/477 (51%), Gaps = 11/477 (2%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 ++I+ ++ V NPAT + + + D KA+ AA A W + A Sbjct: 9 MYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERA---QPEWEALPA 65 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 ER L K++ + + ++ + GGK Q V++ Y A WA + G Sbjct: 66 IERASWLRKISAGIRERASEISALIVEEGGK-IQQLAEVEVAFTADYIDYMAEWARRYEG 124 Query: 160 MTIPVDG---DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTP 216 I D + F R +GV I+PWNFP + A K+APAL GNT+VIKP+E TP Sbjct: 125 EIIQSDRPGENILLFKR--ALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFTP 182 Query: 217 LSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAG 276 +A+ ++ E G P GV N++ G G T G +A + + ++ TGS G+ I A Sbjct: 183 NNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMATAA 242 Query: 277 RSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEF 336 + N+ +V LELGGK+P I+ DADL+ AV+ N GQ C R++V++ IY++F Sbjct: 243 K-NITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQF 301 Query: 337 VRRSVERAKRRVVGSPFDPT-TEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 V R E + G+P + GP I+ ++ + + V EGA++ GGK + K Sbjct: 302 VNRLGEAMQAVQFGNPAERNDIAMGPLINAAALERVEQKVARAVEEGARVAFGGKAVEGK 361 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 G++ PT+ +V +M I EE FGPV ++ F T+++ I AN+SD+GL ++++T ++N Sbjct: 362 GYYYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDAISMANDSDYGLTSSIYTQNLN 421 Query: 456 KALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 A+ ++ G +IN N Q G++ SG G G+ GL EY + + V ++ Sbjct: 422 VAMKAIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLHEYLQTQVVYLQ 478 >3K2W-A nrPDB Length = 497 Score = 256 bits (654), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 165/488 (33%), Positives = 252/488 (51%), Gaps = 16/488 (3%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 +L K FI ++ S + +P+TG+ + E+ KAD + A++ +A + Sbjct: 7 DLHFKNKVNFIGGQYVPSNESDTIDILSPSTGKVIGEIPAGCKADAENALE---VAQAAQ 63 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 W ++ A R +L A+ + ++ +LA M GK L +++ Y Sbjct: 64 KAWAKLTARTRQNMLRTFANKIRENKHILAPMLVAEQGK-LLSVAEMEVDVTATFIDYGC 122 Query: 152 GWADKIHGMTIPVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 A I G +P D D + P GV I WNFPL + KI PAL GNT+V+K Sbjct: 123 DNALTIEGDILPSDNQDEKIYIHKVPRGVVVGITAWNFPLALAGRKIGPALITGNTMVLK 182 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 P ++TPL+ +G + KEAG P GV+N++ G G G + I TGST GK Sbjct: 183 PTQETPLATTELGRIAKEAGLPDGVLNVINGTGSVVGQTLCESPITKMITMTGSTVAGKQ 242 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 I + + + V LELGGK+P ++ DADLD A E A G F N GQ CT R++V Sbjct: 243 IYKTSAEY-MTPVMLELGGKAPMVVMDDADLDKAAEDALWGRFANCGQVCTCVERLYVHA 301 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 S+Y+EF+ + + K VG P D ++ GP+ ++++ + I ++ + +GA + GGK Sbjct: 302 SVYDEFMAKFLPLVKGLKVGDPMDADSQMGPKCNQREIDNIDHIVHEAIKQGATVATGGK 361 Query: 391 GLGRKGF----FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLV 446 +GF + EPTV +V D + EE FGP+ I++ +M++ IE N+S +GL Sbjct: 362 TATVEGFEGGCWYEPTVLVDVKQDNIVVHEETFGPILPIVKVSSMEQAIEFCNDSIYGLS 421 Query: 447 AAVFTN---DINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREY 503 A V T +IN+A+ S ++ G V+IN Q G+K SG G E G+FGL +Y Sbjct: 422 AYVHTQSFANINQAI---SDLEVGEVYINRGMGEQHQGFHNGWKQSGFGGEDGKFGLEQY 478 Query: 504 SEVKTVTV 511 E KTV + Sbjct: 479 LEKKTVYI 486 >2W8P-A nrPDB Length = 487 Score = 255 bits (652), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 173/481 (35%), Positives = 253/481 (52%), Gaps = 20/481 (4%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 T F+ W + + FPV +PA+G + V + + AV+AA AF WR + Sbjct: 13 TDSFVGGRWLPAAA--TFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 67 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW---- 153 A ER LL K +L+ +++ LA + + GKP +A G I ++ W Sbjct: 68 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEA-----HGEILYSAFFLEWFSEE 122 Query: 154 ADKIHGMTIPVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPA 212 A +++G I D +PIGV I PWNFP M K+ AL G TVV+KPA Sbjct: 123 ARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPA 182 Query: 213 EQTPLSALYMGALIKEAGFPPGVINILPGYGPTA---GAAIASHIGIDKIAFTGSTEVGK 269 E TP SAL + L +AG P GV N++P A G AI + + KI+FTGST GK Sbjct: 183 EDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGK 242 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 ++ A S +KRV++ELGG +P I+F A++D AV A F N GQ ++ V+ Sbjct: 243 ILLHHAANS-VKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTAVCSNQFLVQ 301 Query: 330 ESIYEEFVRRSVERAKRRV-VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 I++ FV+ E K+ + VG+ F+ T QGP I++K K+ + + V++GA + G Sbjct: 302 RGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTG 361 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 GK F EPT+ NVT DM EE FGP+ +++F T +E I AN +D GL Sbjct: 362 GKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGY 421 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 ++ D + V+ ++ G V +N + + PFGG K SG GRE ++G+ EY E+K Sbjct: 422 FYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKY 481 Query: 509 V 509 V Sbjct: 482 V 482 >3RH9-A nrPDB Length = 506 Score = 250 bits (639), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 168/477 (35%), Positives = 257/477 (53%), Gaps = 19/477 (3%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 +I W++S G F VYNPATG + +V + D+ AV+A + A L + W Sbjct: 15 YIGGRWKDSAGGATFDVYNPATGSVIAKVPSMPEEDVVAAVEAGQSALRLTNPW---PIE 71 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT----FRYYAGWADK 156 R + L+ + D ++ +R + + + GKP+ +A QG + F Y A Sbjct: 72 TRRKWLEDIRDGLKENREEIGRILCMEHGKPWKEA-----QGEVDYAAGFFDYCAKHISA 126 Query: 157 IHGMTIPVDGDYFTFTRH-EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 + TIP T+T H P+GV G I+PWNFP+ M A K++ AL G VIKPA +T Sbjct: 127 LDSHTIPEKPKDCTWTVHYRPVGVTGLIVPWNFPIGMIAKKLSAALAAGCPSVIKPASET 186 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-KLIQEA 274 PL+ + +++ + P G++N++ G G + H + ++FTGSTEVG KLI + Sbjct: 187 PLTMIAFFSVMDKLDLPDGMVNLVMGKASVIGKVLCEHKDVPMLSFTGSTEVGRKLIVDT 246 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 A +K++ LELGG +P I+F DADL+ A + F GQ C +RIFV E + + Sbjct: 247 A--EQVKKLALELGGNAPFIVFDDADLEAAADNLIANKFRGGGQTCVCANRIFVHEKVAD 304 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG--L 392 F ++ ER + VG + + GP I+K+ ++K+ +Q + +GA L G + L Sbjct: 305 AFGQKLAERVNKMTVGDGMNDGIDIGPLINKQGFDKVKRHLQDALDKGASLVAGKQPAEL 364 Query: 393 GRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452 G G F PTV V +M +EE FGP+ + F+T +EVI+ N+++FGL + VFT Sbjct: 365 G-DGLFFPPTVVQGVDREMCCYQEETFGPLVPMALFRTEEEVIDAGNDTEFGLASYVFTA 423 Query: 453 DINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 D +A V++ ++ G V N ++PFGG K SG GRE G GL E+ E +TV Sbjct: 424 DAERAQRVAAGLRFGHVGWNTGTGPTPEAPFGGMKASGIGREGGLEGLFEFVEAQTV 480 >3PRL-A nrPDB Length = 505 Score = 246 bits (628), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 166/462 (35%), Positives = 236/462 (51%), Gaps = 22/462 (4%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 I N EW S +G + PA+G + + + +++ A+Q A+ A +W+ Sbjct: 14 ILRNGEWVESRTGERISISAPASGVALGSIPALSQEEVNDAIQGAKDA---QKIWKIRPI 70 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 ER LL ADL+E + ++ + KP A ++ R+ A A +++G Sbjct: 71 HERVDLLYAWADLLEERKEIIGELIMHEVAKPKKSAIG-EVSRTADIIRHTADEALRLNG 129 Query: 160 MTIPVDGDYF--------TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 T+ GD F EP+GV I P+N+P+ + A KIAPAL GNTVV KP Sbjct: 130 ETL--KGDQFKGGSSKKIALVEREPLGVVLAISPFNYPVNLAAAKIAPALVTGNTVVFKP 187 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 A Q LS + M + +AG P G+I ++ G G G + H GID I FTG T G+ I Sbjct: 188 ATQGSLSGIKMVEALADAGAPEGIIQVVTGRGSVIGDHLVEHPGIDMITFTGGTTTGERI 247 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331 E ++ + V LELGGK P I+ DADL Q G F GQ CTA R+FV++S Sbjct: 248 SE---KAKMIPVVLELGGKDPAIVLDDADLKLTASQIVSGAFSYSGQRCTAIKRVFVQDS 304 Query: 332 IYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG 391 + ++ V E ++ VGSP D + P ID+K I LI + GA L G K Sbjct: 305 VADQLVANIKELVEQLTVGSPED-DADITPVIDEKSAAFIQGLIDDALENGATLLSGNK- 362 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 R+G + PT+ +VT MR+A EE FGPV I+R K +E I +N SD+GL A++FT Sbjct: 363 --RQGNLLSPTLLDDVTPAMRVAWEEPFGPVLPIIRVKDANEAISLSNQSDYGLQASIFT 420 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNG 492 D ++A+ + ++ GTV IN PF G K SG G Sbjct: 421 KDTDRAINIGKHLEVGTVHINAKTERGPDHFPFLGVKKSGLG 462 >5X5U-A nrPDB Length = 505 Score = 246 bits (627), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 163/482 (33%), Positives = 243/482 (50%), Gaps = 8/482 (1%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 N+ T++ I+ EW ++ SG+ V NPATG+ + V A AD+D+A+ AA+ F Sbjct: 27 NVTYTDTQLLIDGEWVDAASGKTIDVVNPATGKPIGRVAHAGIADLDRALAAAQSGFE-- 84 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 WR++ A ER + K A LV +A + + GKP +A V++ ++A Sbjct: 85 -AWRKVPAHERAATMRKAAALVRERADAIAQLMTQEQGKPLTEA-RVEVLSAADIIEWFA 142 Query: 152 GWADKIHGMTIPVD--GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 +++G +P G T + EP+G PWNFP+ K++ AL G + ++ Sbjct: 143 DEGRRVYGRIVPPRNLGAQQTVVK-EPVGPVAAFTPWNFPVNQVVRKLSAALATGCSFLV 201 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 K E+TP S + +AG P GVI ++ G + + H I K+ FTGST VGK Sbjct: 202 KAPEETPASPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGK 261 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 + AG ++KR T+ELGG +P I+ DAD+ AV+ A F N GQ C + +R V Sbjct: 262 QLASLAGL-HMKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLVH 320 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 SI +EF R V+ A+ VG+ + T G + ++ + +I + GA +E GG Sbjct: 321 NSIRDEFTRALVKHAEGLKVGNGLEEGTTLGALANPRRLTAMASVIDNARKVGASIETGG 380 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 + +G +G F PTV +NV D + E FGPV I F ++E I AN FGL Sbjct: 381 ERIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKLEEAIAEANRLPFGLAGYA 440 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 FT ++ ++ G +WIN + PFGG K SG G E G L Y K+V Sbjct: 441 FTRSFANVHLLTQRLEVGMLWINQPATPWPEMPFGGVKDSGYGSEGGPEALEPYLVTKSV 500 Query: 510 TV 511 TV Sbjct: 501 TV 502 >1T90-A nrPDB Length = 486 Score = 244 bits (622), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 165/490 (33%), Positives = 249/490 (50%), Gaps = 19/490 (3%) Query: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93 EI+ K +IN EW S++ + V NPAT E +C+V + K DID A Q A AF Sbjct: 2 EIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFK---T 58 Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153 W ++ R R+L L+ + + LA + ++ GK +A +G I+ + AG Sbjct: 59 WSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALGEVGRG-IENVEFAAGA 117 Query: 154 ADKIHGMTI-PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPA 212 + G ++ + D PIGV G I P+NFP+++ W A+ GNT ++KP+ Sbjct: 118 PSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPS 177 Query: 213 EQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQ 272 E+TPL + L ++AG P GV N++ G I H I I+F GS VG+ + Sbjct: 178 ERTPLLTEKLVELFEKAGLPKGVFNVVYGAHDVVNG-ILEHPEIKAISFVGSKPVGEYVY 236 Query: 273 EAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESI 332 + G NLKRV G K+ I+ DA+L+ V F + G+ C A + + VEE I Sbjct: 237 KK-GSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGI 295 Query: 333 YEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK-G 391 +EF+ + E+ +G+ D GP I + + L I+ G+ EGA+L C G+ Sbjct: 296 ADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKRTLSYIEKGLEEGARLVCDGREN 355 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 + G+F+ PT+F NVT +M I K+EIF PV ++R K + E IE AN S+F A +FT Sbjct: 356 VSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKNLKEAIEIANKSEFANGACLFT 415 Query: 452 NDINKALTVSSAMQAGTVWINC-YNALNAQSPFGGFKMS------GNGREMGEFGLREYS 504 ++ N + AG + IN A A PF G+K S NG++ +F Y+ Sbjct: 416 SNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFFGTLHANGKDSVDF----YT 471 Query: 505 EVKTVTVKIP 514 K VT + P Sbjct: 472 RKKVVTARYP 481 >5VBF-A nrPDB Length = 478 Score = 239 bits (611), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 154/473 (32%), Positives = 231/473 (48%), Gaps = 6/473 (1%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 +++I+ + +++ R PV +P T + E+ A DID AVQAA AF WR Sbjct: 8 RLYIDGRFHDADGRRTQPVVDPGTTRVLGELPHATAHDIDAAVQAAHRAFV---TWRHES 64 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 R LL + A L + +++ GKP +A ++ + ++A + + Sbjct: 65 PLVRSDLLRRAAALARERAETIGRHITMDQGKPLREAI-AEVVSAAEQLEWHAEEGRRTY 123 Query: 159 GMTIPVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G +P D EPIGVC PWNFP KIA AL G T+V+K E++P Sbjct: 124 GRVVPARSPDVMQTVLREPIGVCAAFSPWNFPFSQAMHKIAAALASGCTLVLKGPEESPS 183 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 + + + L +AG PPG +NI+ G + + KI+FTGS VGK + A Sbjct: 184 AIVALAQLFHDAGLPPGCLNIVWGVPGDVSKQLIEAPQVRKISFTGSVPVGKQLAALAA- 242 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 S +KR+T+ELGG +P ++ ADAD++ A F N GQ C + +R FV+ + ++ FV Sbjct: 243 SLMKRMTMELGGHAPVLVCADADVERAAAMLAAYKFRNAGQVCVSPTRFFVQRAAFDRFV 302 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 397 ++ VG D GP ++ ++I + A+GA++ GG L G Sbjct: 303 CAYLDAVGTIRVGYGLDAGVTMGPLAHARRVDEIDAFVADATAKGAQIATGGMRLPGPGH 362 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457 + PTV T D R+ +E FGP+ I+ F +D+ + AN FGL + FT A Sbjct: 363 YFAPTVVLGPTRDTRLMNDEPFGPIVGIVPFDDLDDALAEANRLPFGLASYAFTTSARNA 422 Query: 458 LTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 +S A++AG V IN + A+ PFGG K SG G E G Y K VT Sbjct: 423 HRISRALEAGMVNINHFGMGPAEIPFGGVKDSGFGSEGGMEAFDGYLVTKFVT 475 >2QE0-A nrPDB Length = 475 Score = 239 bits (609), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 161/490 (32%), Positives = 245/490 (50%), Gaps = 30/490 (6%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 K K ++N EW+ SE+ +Y PA+G ++ V ++D +A+ A WR Sbjct: 3 KQYKNYVNGEWKLSENE--IKIYEPASGAELGSVPAMSTEEVDYVYASAKKA---QPAWR 57 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT---FRYYAG 152 + ER L K+AD++ RD+ + + S K + A + V++T Y A Sbjct: 58 ALSYIERAAYLHKVADILMRDKEKIGAILSKEVAKGYKSA----VSEVVRTAEIINYAAE 113 Query: 153 WADKIHGMTIPVDGDYF--------TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCG 204 ++ G + +G F R EP+G+ I P+N+P+ + KIAPAL G Sbjct: 114 EGLRMEGEVL--EGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAG 171 Query: 205 NTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGS 264 N + KP Q +S L + EAG P GV N + G G G I H ++ I FTGS Sbjct: 172 NVIAFKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGS 231 Query: 265 TEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS 324 T +G+ I + AG ++ + L LGGK I+ DADL+ + G F GQ CTA Sbjct: 232 TGIGERIGKMAG---MRPIMLALGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVK 288 Query: 325 RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 R+ V ES+ +E V + E+ +G+P D + P ID K + + LI +GA Sbjct: 289 RVLVMESVADELVEKIREKVLALTIGNPED-DADITPLIDTKSADYVEGLINDANDKGA- 346 Query: 385 LECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG 444 + R+G I P +F VT DMR+A EE FGPV I+R +++E IE +N S++G Sbjct: 347 --TALTEIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYG 404 Query: 445 LVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREY 503 L A++FTND +A ++ ++ GTV IN + PF G K SG G + ++ + Sbjct: 405 LQASIFTNDFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAM 464 Query: 504 SEVKTVTVKI 513 + VK+V I Sbjct: 465 TTVKSVVFDI 474 >3R64-A nrPDB Length = 508 Score = 238 bits (608), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 174/489 (35%), Positives = 255/489 (52%), Gaps = 15/489 (3%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 I TK I +W S R+ NP + E ++A AD+D A +AA+ A + W Sbjct: 10 IDATKHLIGGQWVEGNSDRISTNINPYDDSVIAESKQASIADVDAAYEAAKKA---QAEW 66 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQA-FYVDLQGVIKTFRYYAGW 153 A+ER ++ + A+L+E R + G +A + L G I + A + Sbjct: 67 AATPAAERSAIIYRAAELLEEHREEIVEWLIKESGSTRSKANLEITLAGNIT--KESASF 124 Query: 154 ADKIHGMTIPVD--GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 ++HG P + G R GV G I PWNFPL + +APAL GN VVIKP Sbjct: 125 PGRVHGRISPSNTPGKENRVYRVAK-GVVGVISPWNFPLNLSIRSVAPALAVGNAVVIKP 183 Query: 212 AEQTPLSALYMGALI-KEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 A TP++ + A I +EAG P GVI+ + G G G +H I+FTGST VG+ Sbjct: 184 ASDTPVTGGVIPARIFEEAGVPAGVISTVAGAGSEIGDHFVTHAVPKLISFTGSTPVGRR 243 Query: 271 IQEAAGRSN-LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 + E A +K V LELGG +P ++ ADAD+D A + A G F +QGQ C + +R+ V+ Sbjct: 244 VGELAINGGPMKTVALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVIVD 303 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 ++++EF+ + VE K G P T GP I+ Q + + E I+ EGA ++ G Sbjct: 304 AAVHDEFLEKFVEAVKNIPTGDPSAEGTLVGPVINDSQLSGLKEKIELAKKEGATVQVEG 363 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 GR + P VFS+VT DM IA+EEIFGP+ +L+ E AN SDFGL AAV Sbjct: 364 PIEGR---LVHPHVFSDVTSDMEIAREEIFGPLISVLKADDEAHAAELANASDFGLSAAV 420 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNA-QSPFGGFKMSGNGREMGEFGLREYSEVKT 508 ++ DI++A + + +G V IN + FGG K SG GR G++ + E++ + Sbjct: 421 WSKDIDRAAQFALQIDSGMVHINDLTVNDEPHVMFGGSKNSGLGRFNGDWAIEEFTTDRW 480 Query: 509 VTVKIPQKN 517 + +K +N Sbjct: 481 IGIKRSAEN 489 >2J5N-A nrPDB Length = 516 Score = 236 bits (602), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 158/430 (36%), Positives = 217/430 (50%), Gaps = 21/430 (4%) Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153 W+ +R RLL K A L+ R + L GK +++A D+ I YYA Sbjct: 90 WKDWPQEDRSRLLLKAAALMRRRKRELEATLVYEVGKNWVEA-SADVAEAIDFIEYYARA 148 Query: 154 ADKIHGMTIPV------DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTV 207 A + + V D + F + P+G I PWNFP+ +F I + GNTV Sbjct: 149 ALRYRYPAVEVVPYPGEDNESF----YVPLGAGVVIAPWNFPVAIFTGMIVGPVAVGNTV 204 Query: 208 VIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEV 267 + KPAE + + + EAGFPPGV+N LPG G GA + H I I FTGS EV Sbjct: 205 IAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPGVGEEVGAYLVEHPRIRFINFTGSLEV 264 Query: 268 GKLIQEAAGR-----SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTA 322 G I EAAGR + KR +E GGK I+ AD D A E + QGQ C+A Sbjct: 265 GLKIYEAAGRLAPGQTWFKRAYVETGGKDAIIVDETADFDLAAEGVVVSAYGFQGQKCSA 324 Query: 323 GSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEG 382 SR+ + + YE + R ++RA+R VG P + + GP + +Q K+L I+ G EG Sbjct: 325 ASRLILTQGAYEPVLERVLKRAERLSVG-PAEENPDLGPVVSAEQERKVLSYIEIGKNEG 383 Query: 383 AKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSD 442 +L GGK L +G+FI PTVF+ V RIA+EEIFGPV ++R K E +E AN++ Sbjct: 384 -QLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQEEIFGPVLSVIRVKDFAEALEVANDTP 442 Query: 443 FGLVAAVFTNDINKALTVSSAMQAGTVWIN--CYNALNAQSPFGGFKMSGNGREMGEFG- 499 +GL V++ G ++ N AL PFGGFK+SG + G Sbjct: 443 YGLTGGVYSRKREHLEWARREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDY 502 Query: 500 LREYSEVKTV 509 LR + E+K V Sbjct: 503 LRLFLEMKAV 512 >4DNG-A nrPDB Length = 485 Score = 226 bits (576), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 150/478 (31%), Positives = 248/478 (51%), Gaps = 12/478 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K FIN +W ESGR + NP + A ++ A A+ A W + Sbjct: 8 KSFINGKWTGGESGRTEDILNPYDQSVITTASLATGKQLEDAFDIAQKA---QKEWAKST 64 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +R +L K + +R + M + G +++ ++L+ I + ++ Sbjct: 65 TEDRKAVLQKARGYLHENRDDIIMMIARETGGTIIKS-TIELEQTIAILDEAMTYTGELG 123 Query: 159 GMT-IPVDGDYFTFTRHE-PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTP 216 G+ +P D + T + P+GV I P+NFP+ + IAPA+ GN+VV KP QT Sbjct: 124 GVKEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGNSVVHKPDIQTA 183 Query: 217 LSA-LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 +S + + AG P GV+N++ G + ++ I+FTGST VG+ I E A Sbjct: 184 ISGGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGMLTNPIPRLISFTGSTAVGRHIGEIA 243 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEE 335 GR+ KR+ LELGG +P + +DAD+D AV+ A G F +QGQ C +RI V + +Y+E Sbjct: 244 GRA-FKRMALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQDVYDE 302 Query: 336 FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 FV + R K+ G DP T GP I+++Q K LE+I+ +G +L GK R Sbjct: 303 FVEKFTARVKQLPYGDQTDPKTVVGPLINERQIEKALEIIEQAKTDGIELAVEGK---RV 359 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 G + P VF ++ +IA+ E+F P+ I++ + E I+ AN++++GL +AVFT+D+ Sbjct: 360 GNVLTPYVFVGADNNSKIAQTELFAPIATIIKAGSDQEAIDMANDTEYGLSSAVFTSDLE 419 Query: 456 KALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 K + + +G +N + ++ + FGG K SG GR + + E++ K ++++ Sbjct: 420 KGEKFALQIDSGMTHVNDQSVNDSPNIAFGGNKASGVGRFGNPWVVEEFTVTKWISIQ 477 >2JG7-A nrPDB Length = 510 Score = 225 bits (574), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 145/476 (30%), Positives = 233/476 (48%), Gaps = 14/476 (2%) Query: 43 NNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASER 102 N W S G V Y PA E + V +A A+ ++ VQ R A+ + W + A +R Sbjct: 27 NGSWGGS--GEVITSYCPANNEPIARVTQATLAEYEETVQKTREAWKM---WADIPAPKR 81 Query: 103 GRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTI 162 G ++ ++ D + + VL ++ SL GK +++ ++Q + Y G + I G + Sbjct: 82 GEIVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVG-EVQEYVDVCDYAVGLSRMIGGPVL 140 Query: 163 PVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALY 221 P + + + P+G+ G I +NFP+ ++ W A AL CGN + K A TPL+++ Sbjct: 141 PSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALTCGNVCLWKGAPTTPLTSVA 200 Query: 222 MGALIKEA---GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 + ++ E PG I + G G A+A +D ++FTGST VGK++ + Sbjct: 201 VTKIVAEVLEQNNLPGAICSMTCGGADIGTAMAKDERVDLLSFTGSTHVGKMVAMMV-QE 259 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 R LELGG + I+F DADL+ V A GQ CT R+ + ES+++ V Sbjct: 260 RFGRKLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESVHDAVVE 319 Query: 339 RSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFF 398 R + K+ +G P+DP+T GP K+ ++ L I+ +G L CGGK + R G + Sbjct: 320 RIAKAYKQVRIGDPWDPSTLYGPLHTKQAVDQYLAAIEQAKQQGGTLVCGGKVMDRPGNY 379 Query: 399 IEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKAL 458 +EPT+ + + D I E F P+ +L+FKT +E N GL +++FT D+ + Sbjct: 380 VEPTIITGLAHDAPIVHTETFVPILYVLKFKTEEEAFAWNNEVQQGLSSSIFTKDLGRVF 439 Query: 459 TV--SSAMQAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 G V +N + FGG K +G GRE G ++Y T T+ Sbjct: 440 RWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTI 495 >3VZ3-A nrPDB Length = 457 Score = 225 bits (574), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 146/454 (32%), Positives = 218/454 (48%), Gaps = 6/454 (1%) Query: 59 NPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRA 118 NP TGE + A+ID + A+ AF +RR S+R + L+ A ++ERD + Sbjct: 10 NPTTGEICQRFKALTPAEIDAKLAKAQEAFQ---AYRRTSFSQRRQWLENAAAILERDTS 66 Query: 119 VLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIG 178 A + + GK Q+ + + RYYA ++ ++ ++P+G Sbjct: 67 KFAEIMTTEMGKTH-QSAIAEAEKSALVCRYYAEHGEQFLANEYTETQATESYVCYQPLG 125 Query: 179 VCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINI 238 + ++PWNFP APAL GN V+K A P AL + A+++ AGFP GV Sbjct: 126 ILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAAGFPEGVFQT 185 Query: 239 LPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFAD 298 L G + + + TGS G + AG+ +K LELGG P ++F Sbjct: 186 LL-IGASQVEQVIKDPRVKAATLTGSEPAGASLASLAGQ-EIKPTLLELGGSDPFVVFPS 243 Query: 299 ADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTE 358 ADLD AVE N GQ A R + E+I EF+ + + +G P P T+ Sbjct: 244 ADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKIGDPMAPETD 303 Query: 359 QGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEI 418 GP + I + VA GAK+ GG+ L R G+F PT+ + + +I +EE+ Sbjct: 304 IGPLATEGILQDISRQVDQAVAAGAKILLGGRPLDRAGYFYPPTILTEIPPGAKILQEEL 363 Query: 419 FGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALN 478 F PV + K +D+ I AN+ FGL A+ +TND + + AG V+IN + Sbjct: 364 FAPVAMVFTVKDLDQAIALANDIPFGLGASAWTNDPAEQQRFIQELDAGAVFINGMVKSD 423 Query: 479 AQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + PFGG K SG GRE+G G+R + KTV +K Sbjct: 424 PRLPFGGTKRSGYGRELGLAGIRTFVNAKTVWLK 457 >5N5S-A nrPDB Length = 515 Score = 219 bits (559), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 147/425 (34%), Positives = 223/425 (52%), Gaps = 26/425 (6%) Query: 101 ERGRLLDKL-ADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 ER +L+K+ A+L R + T+ ++ GKP A ++ I TF+ A + +I+G Sbjct: 99 ERKAVLEKVVAELKNRFEEIAQTL-TMESGKPIKDA-RGEVTRTIDTFQVAAEESVRIYG 156 Query: 160 MTIPVDGDYFT-----FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 IP+D + PIG + PWNFPL + A K+APA+ G V+KPA + Sbjct: 157 EHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASR 216 Query: 215 TPLSALYMGALI-KEAGFPPGVINILPGYGPTAGAAIASHIGIDK----IAFTGSTEVGK 269 TPLSAL +G ++ K P G +ILP A +D+ + FTGS +G Sbjct: 217 TPLSALILGEILHKIEELPLGAFSILP-----VSREDADMFTVDERFKLLTFTGSGPIGW 271 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 ++ AG+ K+V +ELGG +P I+ DLDY +++ G F+ GQ C R++V Sbjct: 272 DMKARAGK---KKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYV 328 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 E +Y+E V K+ +G+PF+ T GP I + I + ++ VA+G KL G Sbjct: 329 HERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVKEAVAKGGKLLTG 388 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 G RKG FIEPTV +V + KEEIFGPV + ++ E ++ NN+ +GL + Sbjct: 389 G---NRKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVKECNNTHYGLQSG 445 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEVK 507 +FT D+NKA M+ G V +N AL S P+GG K SG RE ++ + + E K Sbjct: 446 IFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREGVKYAMDDMLETK 505 Query: 508 TVTVK 512 + ++ Sbjct: 506 VLVMR 510 >1UXV-A nrPDB Length = 501 Score = 218 bits (556), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 152/481 (31%), Positives = 234/481 (48%), Gaps = 24/481 (4%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW--RRMD 98 ++ EW S G+ V +P + +V + ++++ + + F G W R M Sbjct: 22 YLAGEWGGS--GQEIEVKSPIDLATIAKVISPSREEVERTLD---VLFKRGR-WSARDMP 75 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +ER +L K AD++ER+ V A + +N GKP A +++ + R KI Sbjct: 76 GTERLAVLRKAADIIERNLDVFAEVLVMNAGKP-KSAAVGEVKAAVDRLRLAELDLKKIG 134 Query: 159 GMTIPVDGDYFTF-----TRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 G IP D Y T R EP+GV I P+N+PL KI + GN VV+KP+ Sbjct: 135 GDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSI 194 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 PL A + +AGFPP I +L G A +A + ++FTGSTEVG+ + + Sbjct: 195 SDPLPAAMAVKALLDAGFPPDAIALLNLPGKEAEKIVADD-RVAAVSFTGSTEVGERVVK 253 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 G +K+ +ELGG P I+ DADLD A ++ +G++ GQ C A + E +Y Sbjct: 254 VGG---VKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVY 310 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 + V +R VG P DPT + GP I ++++ I+ V +G ++ GG+ LG Sbjct: 311 GKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLG 370 Query: 394 RKGFFIEPTVFSNVTD---DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 +++PT+ D DM + K E+F PV + K +D+ IE AN +GL AAVF Sbjct: 371 PT--YVQPTLVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVF 428 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 D+ K ++ G ++IN PFGG K SG RE + + + KT+ Sbjct: 429 GRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTI 488 Query: 510 T 510 Sbjct: 489 V 489 >3VZ0-A nrPDB Length = 459 Score = 216 bits (551), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 146/421 (34%), Positives = 208/421 (49%), Gaps = 9/421 (2%) Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFY-VDLQGVIKTFRYYAG 152 W+ ++R ++ + ADL+ RDR A++ + GK A +D+ I +F YA Sbjct: 44 WKLRSIAQRKEIVSRAADLLRRDRQHHASLIATEMGKALPDALEEIDVTADILSF--YAN 101 Query: 153 WADKIHGMT-IPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 A++ T + V ++P+G+ I PWNFP A P L GN V+ K Sbjct: 102 GAEEFLAPTPLKVKTGQAKII-NQPLGIIYCIEPWNFPYYQLARVAGPNLMAGNVVIAKH 160 Query: 212 AEQTPLSALYMGALIKEAGFPPGVI-NILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 A P AL L +AG P G NI A + I +A TGS E Sbjct: 161 APNVPQCALAFEKLFHDAGAPVGAYANIF--LDNDQSAELIKDERIRGVALTGS-ERAGQ 217 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 A + LK+ T+ELGG I+ DADLD AV+ A G F N GQ CTA R+ V E Sbjct: 218 AVAAQAGAALKKDTMELGGSDAFIVLDDADLDLAVKWAVWGRFANNGQVCTAAKRMIVHE 277 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 +Y+ F+ R +G+P D T GP + L+ V GA L GGK Sbjct: 278 KVYDAFLDGLKTAITRFRIGNPLDRDTTHGPMSSLRAMELALDQTAEAVKGGATLVAGGK 337 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 + RKGFF+EPT+ ++V+ D + +EIFGPV + + + I+ AN+S +GL AVF Sbjct: 338 RMDRKGFFMEPTILTDVSKDNPVFYQEIFGPVAVVHKVASEQAAIDLANDSPYGLGGAVF 397 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 + DI +A V+ ++ G V+IN A + PFGG K SG GRE+ G+ E+ K V Sbjct: 398 SRDIARAEKVAEQVETGMVFINTATAAAPELPFGGIKNSGFGRELSFLGIEEFINRKLVR 457 Query: 511 V 511 + Sbjct: 458 I 458 >4X0T-A nrPDB Length = 513 Score = 214 bits (545), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 148/480 (30%), Positives = 230/480 (47%), Gaps = 22/480 (4%) Query: 43 NNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASER 102 N W G V Y PA E + V++A AD ++ V+ AR A+ +W + A +R Sbjct: 30 NGSWGGR--GEVITTYCPANNEPIARVRQASVADYEETVKKAREAWK---IWADIPAPKR 84 Query: 103 GRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTI 162 G ++ ++ D + VL ++ SL GK ++ ++Q + Y G + I G + Sbjct: 85 GEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVG-EVQEYVDICDYAVGLSRMIGGPIL 143 Query: 163 PVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALY 221 P + + + P+G+ G I +NFP+ ++ W A A+ CGN + K A T L ++ Sbjct: 144 PSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVA 203 Query: 222 MGALIK---EAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK----LIQEA 274 + +I E PG I L G G A+A ++ ++FTGST+VGK ++QE Sbjct: 204 VTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQER 263 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 GRS LELGG + I F DADL V A GQ CT R+F+ ESI++ Sbjct: 264 FGRS-----LLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHD 318 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGR 394 E V R + + VG+P+DP GP K+ + L ++ EG + GGK + R Sbjct: 319 EVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDR 378 Query: 395 KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDI 454 G ++EPT+ + + D IA E F P+ + +FK +EV N GL +++FT D+ Sbjct: 379 PGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDL 438 Query: 455 NKALTV--SSAMQAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 + G V +N + FGG K +G GRE G ++Y T T+ Sbjct: 439 GRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTI 498 >5JRY-A nrPDB Length = 485 Score = 213 bits (543), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 139/426 (32%), Positives = 214/426 (50%), Gaps = 16/426 (3%) Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 R + A +R +LD LA + GKP A ++ +I TFR + A Sbjct: 66 RELPAYKRQAVLDHCVARFRERFDELAEALCIEAGKPINDA-KGEVTRLIDTFRVASEEA 124 Query: 155 DKIHGMTIPVD-----GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 +I G + ++ Y +TR PIG C I P+NFPL + A K+APAL G V+ Sbjct: 125 VRIDGEVLNLEISARAQGYTGYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVL 184 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPA +TP+ AL +G ++ E P G ++LP + A + ++FTGS VG Sbjct: 185 KPASRTPVGALIIGEVLAETDLPKGAFSVLPAHRDGAD-LFTTDDRFRLLSFTGSPAVGW 243 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADA--DLDYAVEQAHQGVFFNQGQCCTAGSRIF 327 ++E AG+ K+V LELGG + I+ AD LDY V++ G F+ GQ C RI Sbjct: 244 ALKEKAGK---KKVVLELGGNAAAIVDADQLDRLDYVVDRLAFGAFYQSGQSCIGVQRIL 300 Query: 328 VEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLEC 387 IY+ + + + + +G P DP+T GP I + + ++ + + VA GAK+ Sbjct: 301 AHADIYDALRDKLIAKTRSLKMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGAKIVA 360 Query: 388 GGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVA 447 GGK G E T+ NV D + ++E FGP+ + +F D+ + R N+SDFGL A Sbjct: 361 GGK---VDGAMFEATLLENVGRDQDLYRKEAFGPIAILEKFDRFDDALARVNDSDFGLQA 417 Query: 448 AVFTNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEV 506 VFT+ + ++ G V IN + + P+GG K SG GRE + + + +E Sbjct: 418 GVFTDSLAHTQQAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTEP 477 Query: 507 KTVTVK 512 + + V+ Sbjct: 478 RLLVVR 483 >4KNA-A nrPDB Length = 495 Score = 212 bits (539), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 149/464 (32%), Positives = 229/464 (49%), Gaps = 20/464 (4%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 T++FI+ W + +G VF NP T E+V E A D+++AV +AR AF+ W + Sbjct: 10 TELFIDGAWVDG-AGPVFASRNPGTNERVWEGASASADDVERAVASARRAFA---AWSAL 65 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 D R ++ + A L+ + LATM GKP +A K + ++ Sbjct: 66 DLDARCTIVKRFAALLVERKEALATMIGRETGKPLWEARTEVASMAAKVDISITAYHERT 125 Query: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 P+ D RH P GV P+NFP + I PAL GNTVV KP+E P Sbjct: 126 GEKRAPM-ADGVAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPG 184 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 A + ++AG P GV+N++ G T G A+A+H ID + FTGS++ G L+ + G Sbjct: 185 VARATVEIWRDAGLPAGVLNLVQGEKDT-GVALANHRQIDGLFFTGSSDTGTLLHKQFGG 243 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY-EEF 336 + LE+GG +P ++ D+D AV A Q F + GQ CT RI V + + F Sbjct: 244 RPEIVLALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGDRF 303 Query: 337 VRRSVERAKRRVVGSPF--DPTTEQGPQIDKKQYNKIL----ELIQSGVAEGAKLECGGK 390 V R + A ++ S F DP G I + ++++ L+ G + +++ Sbjct: 304 VARLADVAS-KITASVFDADPQPFMGAVISARAASRLVAAQARLVGLGASPIIEMKQRDP 362 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 LG F+ + +VT+ + EE FGP+ +I+R+ +D+ I RAN++ FGL A + Sbjct: 363 ALG----FVNAAIL-DVTNVRELPDEEHFGPLAQIVRYTDLDDAIARANDTAFGLSAGLL 417 Query: 451 TNDINKALTVSSAMQAGTV-WINCYNALNAQSPFGGFKMSGNGR 493 +D T A++AG V W N ++ +PFGG SGN R Sbjct: 418 ADDEQAWHTFRRAIRAGIVNWNRPTNGASSAAPFGGAGRSGNHR 461 >3EFV-A nrPDB Length = 462 Score = 211 bits (537), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 146/454 (32%), Positives = 221/454 (48%), Gaps = 12/454 (2%) Query: 59 NPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRA 118 NPATG+ + + A+ +I+ A+ A F W+ ++R + L + + Sbjct: 13 NPATGQTLAAMPWANAQEIEHALSLAASGFK---KWKMTSVAQRAQTLRDIGQALRAHAE 69 Query: 119 VLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIG 178 +A + GKP QA ++ +YA + + + + P+G Sbjct: 70 EMAQCITREMGKPIKQA-RAEVTKSAALCDWYAEHGPAMLNPEPTLVENQQAVIEYRPLG 128 Query: 179 VCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINI 238 V I+PWNFPL P L GN+ ++K A A + ++ EAG P GV Sbjct: 129 VILAIMPWNFPLWQVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEAGTPAGVY-- 186 Query: 239 LPGYGPTAGAAIASHIGIDKIA---FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNII 295 G+ ++ I +IA TGS G I A + LK+ LELGG P I+ Sbjct: 187 --GWVNANNEGVSQMINDPRIAAVTVTGSVRAGAAIGAQA-GAALKKCVLELGGSDPFIV 243 Query: 296 FADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDP 355 DADL+ AV+ A G + N GQ C A R VEE I + F R V A +G P Sbjct: 244 LNDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAFTDRFVAAAAALKMGDPLVE 303 Query: 356 TTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAK 415 + GP +++ + +Q+ VAEGA+L GG+ + +G + TV ++VT DM + Sbjct: 304 ENDLGPMARFDLRDELHQQVQASVAEGARLLLGGEKIAGEGNYYAATVLADVTPDMTAFR 363 Query: 416 EEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYN 475 +E+FGPV I K + AN+S+FGL A +FT D A +++ ++ G V+IN Y+ Sbjct: 364 QELFGPVAAITVAKDAAHALALANDSEFGLSATIFTADDTLAAEMAARLECGGVFINGYS 423 Query: 476 ALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 A +A+ FGG K SG GRE+ FGL E+ V+TV Sbjct: 424 ASDARVAFGGVKKSGFGRELSHFGLHEFCNVQTV 457 >5KF0-A nrPDB Length = 485 Score = 211 bits (536), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 138/426 (32%), Positives = 215/426 (50%), Gaps = 16/426 (3%) Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 R + A R +LD LA + GKP + ++ +I TFR + A Sbjct: 66 RELPAYRRQAVLDHCVARFRERFDELAEALCIEAGKP-INDSRGEVTRLIDTFRVASEEA 124 Query: 155 DKIHGMTIPVD-----GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 +I G + ++ Y +TR PIG C I P+NFPL + A K+APAL G V+ Sbjct: 125 VRIDGEVLNLEISARAQGYTGYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVL 184 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPA +TP+ AL + ++ E P G ++LP + A + ++FTGS VG Sbjct: 185 KPASRTPVGALIIAEVLAETNLPKGAFSVLPAHRDGAD-LFTTDERFRLLSFTGSPAVGW 243 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADA--DLDYAVEQAHQGVFFNQGQCCTAGSRIF 327 ++E AG+ K+V LELGG + I+ AD LDY V++ G ++ GQ C RI Sbjct: 244 ALKEKAGK---KKVVLELGGNAAAIVDADQFEQLDYVVDRLAFGAYYQSGQSCIGVQRIL 300 Query: 328 VEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLEC 387 V S+Y+ + V + + +G P DP+T GP I + + ++ + + VA GAK+ Sbjct: 301 VHASLYDTLRDKLVAKTRSLKMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGAKIIA 360 Query: 388 GGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVA 447 GGK G E T+ +V + + ++E FGPV + +F D+ + R N+SDFGL A Sbjct: 361 GGK---VDGAMFEATLLEDVGREQDLYRKEAFGPVAILEKFDRFDDALARVNDSDFGLQA 417 Query: 448 AVFTNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEV 506 VFT+ + A ++ G V IN + + P+GG K SG GRE + + + +E Sbjct: 418 GVFTDSLTHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTEP 477 Query: 507 KTVTVK 512 + + V+ Sbjct: 478 RLMVVR 483 >5TJR-A nrPDB Length = 531 Score = 211 bits (536), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 149/479 (31%), Positives = 245/479 (51%), Gaps = 15/479 (3%) Query: 49 SESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDK 108 +++GR V+NP+TGE V +V AD+ + +A+ AA+ AF WR ++R ++L + Sbjct: 47 ADTGRTADVFNPSTGEAVRKVPLADRETMQQAIDAAKAAFP---AWRNTPPAKRAQVLFR 103 Query: 109 LADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG-MTIPVDGD 167 L+E + + + S GK A +L+ I+ Y + + G + V + Sbjct: 104 FKQLLEANEERIVKLISEEHGKTIEDA-AGELKRGIENVEYATAAPEILKGEYSRNVGPN 162 Query: 168 YFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK 227 ++ +PIGV I P+NFP ++ W A+ CGNT ++KP+E+ P S L + L Sbjct: 163 IDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPSSTLLIAELFH 222 Query: 228 EAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLEL 287 EAG P GV+N++ G A I + + ++F GST + + I + G KRV Sbjct: 223 EAGLPKGVLNVVHGDKGAVDALIEAP-EVKALSFVGSTPIAEYIY-SEGTKRGKRVQALG 280 Query: 288 GGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS-RIFVEESIYEEFVRRSVERAKR 346 G K+ ++ DADLD AV + + G+ C A S + V + I + V++ V + K Sbjct: 281 GAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQIADALVQKLVPQIKG 340 Query: 347 RVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL----GRKGFFIEPT 402 +G+ + GP + +K+ I +GVA+GA+L G+G GFF+ T Sbjct: 341 LKIGAGTSCGLDMGPLVTGAARDKVTGYIDTGVAQGAELVVDGRGYKVAGHENGFFLGGT 400 Query: 403 VFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSS 462 +F VT +M I KEEIFGPV I+R +++E ++ N+ ++G +FT D A Sbjct: 401 LFDRVTPEMTIYKEEIFGPVLCIVRVNSLEEAMQLINDHEYGNGTCIFTRDGEAARLFCD 460 Query: 463 AMQAGTVWINCYNALN-AQSPFGGFKMS--GNGREMGEFGLREYSEVKTVTVKIPQKNS 518 ++ G V +N + A FGG+K S G+ G G+R Y++ K +T + PQ+ S Sbjct: 461 EIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTKRKAITQRWPQRKS 519 >5U0M-A nrPDB Length = 497 Score = 207 bits (527), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 149/458 (32%), Positives = 219/458 (47%), Gaps = 11/458 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 ++I+ W G F P TGE V + A D+D AV+ AR AF WRR Sbjct: 13 NVYIDGLWLPGH-GAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFL---AWRRKS 68 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +ER +++ +L+E ++ LA L GKP ++ ++ ++ ++ Sbjct: 69 LAERQAVIEAFGELLEANKEELAHQIGLETGKPLWES-RTEVAAMMGKIPISVKAYNERT 127 Query: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 G T RH P GV P+NFP + I PAL GNTVV KP+E TP Sbjct: 128 GHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGV 187 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 A L ++AG P GVIN++ G G G +A H ID + FTGS+ VG L+ E G Sbjct: 188 AELTVRLWEKAGLPDGVINLVQG-GSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGGQ 246 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY-EEFV 337 K + LE+GG +P I+ +DLD AV A Q F + GQ CT R+ V + +EF+ Sbjct: 247 PEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFL 306 Query: 338 RRSVERAKRRVVGS-PFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKG 396 R VE A R V DP G I + N++L+ + + +GA K L Sbjct: 307 ARLVEVAARITVAEFDADPQPFMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPDT 366 Query: 397 FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINK 456 + P + + + +E FGP+ + R+K DE +E ANN+ +GL A + ++D Sbjct: 367 GLLSPGIVD--ATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAGILSDDRKL 424 Query: 457 ALTVSSAMQAGTV-WINCYNALNAQSPFGGFKMSGNGR 493 + ++AG V W ++ +PFGG SGN R Sbjct: 425 YNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHR 462 >4I3V-A nrPDB Length = 488 Score = 204 bits (520), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 134/373 (35%), Positives = 191/373 (51%), Gaps = 24/373 (6%) Query: 160 MTIPVDGDYFT------------FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTV 207 M I DG+ F+ FT EP+ I P+N PL M A K+APA+ N V Sbjct: 122 MCIRDDGEIFSCDLTPHGKARKIFTMREPLTAISAITPFNHPLNMVAHKVAPAIATNNCV 181 Query: 208 VIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEV 267 V+KP E TP++AL + ++ EAG PP +++++ G+ G + ++ +D + FTGS V Sbjct: 182 VVKPTELTPMTALLLADILYEAGLPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPV 241 Query: 268 GKLIQEAAGRSNLKRVTLELGGKSPNII---FADADLDYAVEQAHQGVFFNQGQCCTAGS 324 GKLI A ++ KR LELGG P II +D DL A + A G N GQ CTA Sbjct: 242 GKLI---AANAHYKRQVLELGGNDPLIILNDLSDDDLARAADLAVAGATKNSGQRCTAVK 298 Query: 325 RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 RI +ES+ + FV +ERAKR G P D +T+ G I +K E + EGA Sbjct: 299 RILCQESVADRFVPLVLERAKRLRFGDPMDRSTDLGTVIHEKAAALFEERVMRAAEEGAD 358 Query: 385 LECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDE-VIERANNSDF 443 + GR G + P V V + EE FGP+ I+R D+ I +N++ F Sbjct: 359 ILYHP---GRSGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDDDDATITLSNSTAF 415 Query: 444 GLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ-SPFGGFKMSGNGREMGEF-GLR 501 GL + V TND + + ++ GTV I + SPFGG K SGNG + G ++ Sbjct: 416 GLSSGVCTNDYRRMQKYIAGLKVGTVNIWEVPGYRIEMSPFGGIKDSGNGYKEGVIEAMK 475 Query: 502 EYSEVKTVTVKIP 514 ++ VKT ++ P Sbjct: 476 SFTNVKTFSLPWP 488 >4OGD-A nrPDB Length = 465 Score = 204 bits (519), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 148/440 (33%), Positives = 213/440 (48%), Gaps = 20/440 (4%) Query: 87 AFSLGSVWRRMDA-SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAF-YVDLQGVI 144 A L WR+ D ER L ++A+++ RDR A + + + GK F +A VDL I Sbjct: 32 AHLLYKKWRKEDHLEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADI 91 Query: 145 KTFRYYAGWADKIHGMTIPVDGDY-FTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCC 203 YYA AD+ M+ P++ D + + GV + PWNFP AP Sbjct: 92 AD--YYADKADEFL-MSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIV 148 Query: 204 GNTVVIKPAEQTPLSALYMGALIKEAGFPPGVI-NILPGYGPTAGAAIASHIGIDK---- 258 GN +V+K A P SA L+ EAG G I N+ Y S + DK Sbjct: 149 GNPMVLKHASICPRSAQSFEELVLEAGAEAGSITNLFISYDQV------SQVIADKRVVG 202 Query: 259 IAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQ 318 + TGS G I E AG+ NLK+ TLELGG II DAD D + + +N GQ Sbjct: 203 VCLTGSERGGASIAEEAGK-NLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQ 261 Query: 319 CCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSG 378 CT+ R V + Y+ F + K G P DP T P + +L+ I+ Sbjct: 262 VCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLA 321 Query: 379 VAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERA 438 + GA+L GG+ + G F+ PT+ + +T D I +EIFGPV EI + + +E IE A Sbjct: 322 LDHGAELVYGGEAIDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVA 381 Query: 439 NNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEF 498 N+S++GL +F+++ A V++ ++ G +IN + PFGG K SG GRE+ E Sbjct: 382 NDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSEL 441 Query: 499 GLREYSEVKTVTVKIPQKNS 518 G + V + IP K + Sbjct: 442 GFTSF--VNEHLIYIPNKTN 459 >3ROS-A nrPDB Length = 484 Score = 203 bits (516), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 137/447 (30%), Positives = 211/447 (47%), Gaps = 10/447 (2%) Query: 59 NPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRA 118 NP T E ID+A+ LA +L WR + + R +L +A+ ++ Sbjct: 10 NPYTNEAFASYDNPTSKQIDEAIN---LAHALYKKWRHEEPASRAEILHDIANALKEHED 66 Query: 119 VLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDY-FTFTRHEPI 177 LA M +L GK L +++ + YYA ++ T ++ D + + Sbjct: 67 ELAKMMTLEMGK-LLSESKEEVELCVSICNYYADHGPEMLKPT-KLNSDLGNAYYLKQST 124 Query: 178 GVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPG-VI 236 GV PWNFPL AP GN +++K A P SA +IK AG P G +I Sbjct: 125 GVIMACEPWNFPLYQVIRVFAPNFIVGNPILLKHAHNVPGSAALTAKIIKRAGAPEGSLI 184 Query: 237 NILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIF 296 N+ P Y A I + I +A TGS G + EAAG+ NLK+ T+ELGG I+ Sbjct: 185 NLYPSYDQLAD--IIADPRIQGVALTGSERGGSAVAEAAGK-NLKKSTMELGGNDAFIVL 241 Query: 297 ADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPT 356 DAD + +N GQ CT+ RI VE+S Y+E + G P + Sbjct: 242 DDADPQVLRNVLNDARTYNDGQVCTSSKRIIVEKSRYDEVLHELKNVFSNLKAGDPLEAD 301 Query: 357 TEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKE 416 T P +K K+ ++ + GAK+ + KG F PT+ +++ D + + Sbjct: 302 TTLPPMNSEKAKEKLEAQVKEAIDAGAKVFYQYPEIDSKGAFFRPTILTDIAKDNPVFDK 361 Query: 417 EIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNA 476 E+FGP+ E+ + + I+ AN+S +GL ++V +DI++A VS+ ++ G IN Sbjct: 362 EVFGPIAEVFVVEDDNAAIQLANDSSYGLGSSVIGSDIDRAKKVSAQIETGMTVINGRWI 421 Query: 477 LNAQSPFGGFKMSGNGREMGEFGLREY 503 + + PFGG K SG GRE+ GL + Sbjct: 422 TSGELPFGGIKKSGYGRELSGLGLMAF 448 >5J6B-A nrPDB Length = 485 Score = 202 bits (513), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 132/401 (32%), Positives = 203/401 (50%), Gaps = 16/401 (3%) Query: 120 LATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTI-----PVDGDYFTFTRH 174 LA + GKP + ++ +I TFR A + +I G + P Y + + Sbjct: 91 LAQALCIEAGKP-INDSKGEVTRLIDTFRVAAEESVRIEGGLVNLEISPRAQGYSGYYKR 149 Query: 175 EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPG 234 PIG C I P+NFPL + A K+APAL G V+KPA +TP+ AL +G ++ E P G Sbjct: 150 VPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRTPIGALIIGEVLAETDLPKG 209 Query: 235 VINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNI 294 +ILP + A + ++FTGS VG E ++ K+V LELGG + I Sbjct: 210 AFSILPAHRDGAD-LFTTDERFKLLSFTGSPTVG---WELKKKAGKKKVVLELGGNAAAI 265 Query: 295 IFADAD--LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSP 352 + AD LDY VE+ G ++ GQ C RI +Y+ + + + + +G P Sbjct: 266 VDADQREVLDYVVERLAFGAYYQSGQSCIGVQRIIAHADVYDALREKLIAKTRSLKMGDP 325 Query: 353 FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMR 412 DP T GP I + + ++ +++ VA GAK+ GGK G E T+ V D Sbjct: 326 KDPATFVGPMISESEARRLAGWMEAAVAAGAKIVAGGK---VDGAMFEATLLEGVGRDQD 382 Query: 413 IAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWIN 472 + ++E FGPV + RF D+ + R N+SDFGL A VFT+ ++ A ++ G V IN Sbjct: 383 LYRKEAFGPVALLERFSDFDDALARVNDSDFGLQAGVFTDSLSHAQRAWDELEVGGVVIN 442 Query: 473 CYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + + P+GG K SG GRE + + + +E++ + V+ Sbjct: 443 DVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTELRLMVVR 483 >4PXN-A nrPDB Length = 525 Score = 198 bits (503), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 142/469 (30%), Positives = 219/469 (46%), Gaps = 13/469 (2%) Query: 51 SGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLA 110 SG +P + + EV EA D ++ ++A F W + A +RG ++ ++ Sbjct: 49 SGPTVTSTSPTNNQVIAEVVEASVHDYEEGMRAC---FDAAKTWMAIPAPKRGEIVRQIG 105 Query: 111 DLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDG-DYF 169 D + L + SL GK L ++Q +I Y G + +++G IP + ++ Sbjct: 106 DALRAKLHHLGRLVSLEMGK-ILPEGIGEVQEIIDMCDYAVGLSRQLNGSIIPSERPNHM 164 Query: 170 TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK-- 227 P+GV G I +NFP + W AL CGN VV K A TPL + M ++ Sbjct: 165 MMEVWNPLGVVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKIVASV 224 Query: 228 -EAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLE 286 E PG I G G AIA I I ++FTGST G ++Q+ + + LE Sbjct: 225 LEKNNLPGAIFTSFCGGTEIGQAIALDIRIPLVSFTGSTRAGLMVQQQV-SARFGKCLLE 283 Query: 287 LGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKR 346 L G + I+ DAD+ AV GQ CT R+ + E+IY+ F+ + VE K+ Sbjct: 284 LSGNNAIIVMDDADIQLAVRSVLFAAVGTAGQRCTTCRRLILHENIYQTFLDQLVEVYKQ 343 Query: 347 RVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSN 406 +G P + T GP L+ IQ+ ++G K+ GG + +G F++PT+ Sbjct: 344 VRIGDPLEKGTLLGPLHTPASKENFLKGIQTIKSQGGKILFGGSAIESEGNFVQPTIVE- 402 Query: 407 VTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN--DINKALTVSSAM 464 +T + KEE+FGPV +++F+T+ E IE N+ GL +++FT DI Sbjct: 403 ITPSAPVVKEELFGPVLYVMKFQTLKEAIEINNSVPQGLSSSIFTKRPDIIFKWLGPHGS 462 Query: 465 QAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 G V +N N FGG K +G GRE G ++Y T T+ Sbjct: 463 DCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRATCTIN 511 >4ZZ7-A nrPDB Length = 501 Score = 197 bits (501), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 144/475 (30%), Positives = 238/475 (50%), Gaps = 15/475 (3%) Query: 49 SESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDK 108 +E+ R V+NPATGE ++ A +++A+ AA+ AF WR +R R++ + Sbjct: 17 TENTRSQNVFNPATGEIGKQLDLASTKTVEQAISAAQHAFP---TWRNTPPLKRARVMFR 73 Query: 109 LADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG-MTIPVDGD 167 +L+E+ + + GK A +LQ I+ Y G + + G + V Sbjct: 74 FKELLEQHADEICRLIGEEHGKIAHDAMG-ELQRGIENVEYACGAPELLKGEHSRNVGPG 132 Query: 168 YFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK 227 +++ +P+GV I P+NFP+++ W A+ CGN V+KP+E+ P S LY+ L++ Sbjct: 133 IDSWSEFQPMGVVAGITPFNFPVMVPLWMFPMAIVCGNCFVLKPSERDPSSTLYIAQLLQ 192 Query: 228 EAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLEL 287 EAG P GV+N++ G A A+ + ++F GST + + I A +N KR Sbjct: 193 EAGLPDGVMNVVNG-DKEAVDALLHDDRVKAVSFVGSTPIAEYIYRTA-SANGKRCQALG 250 Query: 288 GGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS-RIFVEESIYEEFVRRSVERAKR 346 G K+ I+ DAD+D AV Q F + G+ C A S + V ++ + V + + ++ Sbjct: 251 GAKNHAIVMPDADMDNAVNQLLGAAFGSSGERCMALSVAVAVGDAAGDALVSKMTQAMQK 310 Query: 347 RVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL----GRKGFFIEPT 402 VG D + GP I ++ K++ I S +GA + G+ GFF+ T Sbjct: 311 LKVGPSTDSGNDFGPVITRQHQEKVIGYINSAEQQGATIVVDGRQPKVPNHENGFFVGGT 370 Query: 403 VFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSS 462 + +VT +M +EEIFGPV +++R TM + ++ + ++G +FT D A S Sbjct: 371 LIDHVTPEMTSYQEEIFGPVLQVVRVATMQDAMDLIDAHEYGNGTCIFTRDGEAARYFSD 430 Query: 463 AMQAGTVWINCYNALN-AQSPFGGFKMS--GNGREMGEFGLREYSEVKTVTVKIP 514 +Q G V IN + A FGG+K S G+ G +R Y++ KTVT + P Sbjct: 431 NIQVGMVGINIPLPVPVAYHSFGGWKRSLFGDLHAYGPDAVRFYTKRKTVTQRWP 485 >4E4G-A nrPDB Length = 521 Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 143/488 (29%), Positives = 229/488 (46%), Gaps = 23/488 (4%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 FI+ + SGRV ++NPATGE V A A A A + W + Sbjct: 30 FIDGKRVAGTSGRVSNIFNPATGEVQGTVALASDA---DLAAAVESAKAAQPKWAATNPQ 86 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW-----AD 155 R R+ K L+ + LA M S GK A ++G ++ + G ++ Sbjct: 87 RRARVFMKFVQLLNDNMNELAEMLSREHGKTIDDAKGDIVRG-LEVCEFVIGIPHLQKSE 145 Query: 156 KIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 G +D ++ +P+G+ I P+NFP ++ W APA+ CGN ++KP+E+ Sbjct: 146 FTEGAGPGID----MYSIRQPVGIGAGITPFNFPGMIPMWMFAPAIACGNAFILKPSERD 201 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 P + + L+ EAG P G++N++ G A AI +H I ++F GST + + + A Sbjct: 202 PSVPIRLAELMIEAGLPAGILNVVNG-DKGAVDAILTHPDIAAVSFVGSTPIARYVYGTA 260 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS-RIFVEESIYE 334 N KR G K+ II DADLD A + + G+ C A S + V E Sbjct: 261 AM-NGKRAQCFGGAKNHMIIMPDADLDQAANALIGAGYGSAGERCMAISVAVPVGEETAN 319 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGR 394 + + V + +G D + GP + K+ +I LI SG+ +GAKL G+ Sbjct: 320 RLIDKLVPMVESLRIGPYTDEKADMGPVVTKEAEQRIRSLIDSGIEQGAKLVVDGRDFKL 379 Query: 395 KGF----FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 +G+ FI +F +VT DM I K EIFGPV ++R + +E + ++G A++ Sbjct: 380 QGYENGHFIGGCLFDDVTPDMDIYKTEIFGPVLSVVRARNYEEALSLPMKHEYGNGVAIY 439 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMS--GNGREMGEFGLREYSEVK 507 T D + A +S + G V +N + A FGG+K S G+ + G ++ ++ K Sbjct: 440 TRDGDAARDFASRINIGMVGVNVPIPVPLAYHSFGGWKSSSFGDLNQHGTDSIKFWTRTK 499 Query: 508 TVTVKIPQ 515 T+T + P Sbjct: 500 TITSRWPS 507 >4H7N-A nrPDB Length = 474 Score = 174 bits (440), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 117/345 (33%), Positives = 175/345 (50%), Gaps = 16/345 (4%) Query: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 P + G I PWNFPL + PAL G VV+KP+E P ++ L+ P + Sbjct: 126 PYPLVGVISPWNFPLTLSMIDTIPALLAGCAVVVKPSEIAPR---FVAPLLMALNTVPEL 182 Query: 236 INIL---PGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSP 292 ++L G G T GA + +++ D + FTGS G+ + E A R + LELGGK P Sbjct: 183 RDVLIFVEGGGET-GANLINYV--DFVCFTGSVATGREVAETAARRFIP-AYLELGGKDP 238 Query: 293 NIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSP 352 I+ A+L+ A G N GQ C + RI+V ES +EEF + + +A R + P Sbjct: 239 AIVLESANLELATSAILWGAVVNTGQSCLSIERIYVAESKFEEFYHQLIAKAHRLQLAYP 298 Query: 353 FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK--GLGRKGFFIEPTVFSNVTDD 410 GP I +KQ I + I V +GA + CGGK LG G++ PTV +NV Sbjct: 299 LVEDGAIGPIIAEKQAGIINDHILDAVEKGAVIHCGGKVEELG-GGWWCRPTVMTNVNHS 357 Query: 411 MRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVW 470 M++ EE FGP+ ++ F ++E + AN++ +GL AAVF ++AL V+ + AG + Sbjct: 358 MKVMTEETFGPIMPVMPFPDVEEAVYLANDTIYGLSAAVFAGSEDEALKVARQLNAGAIS 417 Query: 471 IN--CYNALNAQSPFGGFKMSG-NGREMGEFGLREYSEVKTVTVK 512 IN A+ + F SG G +G GL+ + + +K Sbjct: 418 INDAALTAMMHEGEKNAFNFSGLGGSRVGAAGLKRFLRKQAFLIK 462 >6DBB-A nrPDB Length = 511 Score = 169 bits (427), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 131/482 (27%), Positives = 227/482 (47%), Gaps = 25/482 (5%) Query: 52 GRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLAD 111 G +P G + + AD ++ + AA AF WR + A RG L+ + Sbjct: 27 GNALTARSPLDGATLATLAVDTPADAERKIDAAHDAFLK---WRTVPAPVRGELVRVFGN 83 Query: 112 LVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVD--GDYF 169 ++ +A L + +L GK + ++Q +I + G + +++G+TI + G Sbjct: 84 VLREHKAELGRLVTLEAGKITSEGLG-EVQEMIDICDFAVGLSRQLYGLTIASERPGHRM 142 Query: 170 TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA 229 T H PIGVCG I +NFP+ ++AW A A CG++VV KP+E+TPL+A+ L+++A Sbjct: 143 METWH-PIGVCGVISAFNFPVAVWAWNAALAFVCGDSVVWKPSEKTPLTAIACHVLLQKA 201 Query: 230 ---------GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNL 280 G P + L G + + + ++ TGS +G+ + + + L Sbjct: 202 LREFEKTHPGVAPAELGQLVLGMRDVGEVLTASKKVPVVSATGSVRMGQEVAKVLSQ-RL 260 Query: 281 KRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRS 340 R LELGG + I+ ADLD V GQ CT R+ V S+ E+ + R Sbjct: 261 ARGILELGGNNGMIVAPSADLDLVVRAVTFAAVGTAGQRCTTLRRLIVHRSLVEQLLPR- 319 Query: 341 VERAKRRV-VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK-GLGR-KGF 397 +E+A V VG+P + T GP +D+ ++ + + + +G +++ G + +G + Sbjct: 320 IEKAYASVKVGNPLEEGTLVGPLVDRASFDAMQKALADAREQGGEVKGGERVDVGHADAY 379 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457 ++ P + + + + E F P+ ++ + D+ I+ N GL +A+FTND+ +A Sbjct: 380 YVRPAIV-RMPKQSAVVERETFAPILYVMVYDNFDDAIDVHNAVPQGLSSAIFTNDMREA 438 Query: 458 LTVSSAM--QAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIP 514 SA G V +N + FGG K +G GRE G + Y T T+ Sbjct: 439 EQFMSAAGSDCGIVNVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKAYMRRATNTINYS 498 Query: 515 QK 516 ++ Sbjct: 499 RQ 500 >3JU8-A nrPDB Length = 490 Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 134/458 (29%), Positives = 206/458 (44%), Gaps = 14/458 (3%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 +I +W + G +P V + AD +D AV AAR AF W R Sbjct: 9 YIAGQWLAGQ-GETLESLDPVGQGVVWSGRGADATQVDAAVCAAREAFP---AWARRPLE 64 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 +R LL++ A ++ LA + GKP ++ V K + ++ Sbjct: 65 QRIELLERFAATLKSRADELARVIGEETGKPLWESATEVTSMVNKVAISVQAFRERTGEK 124 Query: 161 TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTP-LSA 219 + P+ D RH+P GV P+NFP + I PAL GN VV KP+E TP ++ Sbjct: 125 SGPL-ADATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTPKVAE 183 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 L + A I +AG P GV+N++ G G G A+A+H G+D + FTGS+ G L+ G Sbjct: 184 LTLKAWI-QAGLPAGVLNLVQG-GRETGVALAAHRGLDGLFFTGSSRTGNLLHSQFGGQP 241 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY-EEFVR 338 K + LE+GG +P ++ ADLD AV Q F + GQ CT R+ V + + + + Sbjct: 242 QKILALEMGGNNPLVVEEVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALLA 301 Query: 339 RSVERAKRRVVGSPFD--PTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKG 396 R V + VG FD P G I +L+ + + +GA+ Sbjct: 302 RLVAVSATLRVGR-FDEQPAPFMGAVISLSAAEHLLKAQEHLIGKGAQPLLAMTQPIDGA 360 Query: 397 FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINK 456 + P + +V+ EE FGP+ +++R+ I AN + +GL A + ++ + Sbjct: 361 ALLTPGIL-DVSAVAERPDEEFFGPLLQVIRYSDFAAAIREANATQYGLAAGLLSDSRER 419 Query: 457 ALTVSSAMQAGTV-WINCYNALNAQSPFGGFKMSGNGR 493 +AG V W + +PFGG SGN R Sbjct: 420 FEQFLVESRAGIVNWNKQLTGAASSAPFGGIGASGNHR 457 >5UCD-A nrPDB Length = 457 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 123/447 (27%), Positives = 209/447 (46%), Gaps = 29/447 (6%) Query: 75 ADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQ 134 A ID A + F+ + D R + L++L + V ++ L + + + GKP Sbjct: 28 AKIDSLFSAQKAYFATRAT---ADVGFRKQSLERLKEAVINNKEALYSALAEDLGKPKDV 84 Query: 135 AFYVDLQGVIKTFRYYAGWADK-IHGMTIP---VDGDYFTFTRHEPIGVCGQIIPWNFPL 190 ++ V+ + D+ + +++P + + EP GV I P+N+P+ Sbjct: 85 VDLAEIGAVLHEIDFALAHLDEWVAPVSVPSPDIIAPSECYVVQEPYGVTYIIGPFNYPV 144 Query: 191 LMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAI 250 + + A+ GNT +IKP+E TP ++ + +I EA F P + ++ G G + + Sbjct: 145 NLTLTPLIGAIIGGNTCIIKPSETTPETSAVIEKIIAEA-FAPEYVAVIQG-GRDENSHL 202 Query: 251 ASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQ 310 S + D I FTGS VGK++ +AA + +L V LELGGK P I+ DADLD V Q Sbjct: 203 LS-LPFDFIFFTGSPNVGKVVMQAAAK-HLTPVVLELGGKCPLIVLPDADLDQTVNQLMF 260 Query: 311 GVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNK 370 G F N GQ A ++V S+ + + R VER K G + ++Q + Sbjct: 261 GKFINSGQTXIAPDYLYVHYSVKDALLERLVERVKTE-----LPEINSTGKLVTERQVQR 315 Query: 371 ILELI---QSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILR 427 ++ L+ Q V G++ + + L TV V + + EE+FGP+ +L Sbjct: 316 LVSLLEATQGQVLVGSQADVSKRALSA-------TVVDGVEWNDPLMSEELFGPILPVLE 368 Query: 428 FKTMDEVIERAN-NSDFGLVAAVFTNDINKALTVSSAMQAGTVWIN--CYNALNAQSPFG 484 F ++ I++ N + L VF D++ A + + +Q+G +N +A + PFG Sbjct: 369 FDSVRTAIDQVNKHHPKPLAVYVFGKDMDVAKGIINQIQSGDAQVNGVMLHAFSPYLPFG 428 Query: 485 GFKMSGNGREMGEFGLREYSEVKTVTV 511 G SG G G F ++ K+V + Sbjct: 429 GIGASGMGEYHGHFSYLTFTHKKSVRI 455 >4OE4-A nrPDB Length = 580 Score = 149 bits (376), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 148/500 (29%), Positives = 233/500 (46%), Gaps = 54/500 (10%) Query: 33 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQV-CEVQEADKADIDKAVQAARLAFSLG 91 L I +I+ NNE +FP NPA +QV V +A + D+ + A + A Sbjct: 62 LVINGERIYDNNE------RALFPQTNPANHQQVLANVTQATEKDV---MNAVKAAKDAK 112 Query: 92 SVWRRMDASERGRLLDKLADLVE---RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFR 148 W + +R + K ADL+ R + ATM L GK QA + + FR Sbjct: 113 KDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM--LGQGKNVYQAEIDCITELSDFFR 170 Query: 149 YYAGWADKIHGMTIPVDGDYFTFTRHE--PI-GVCGQIIPWNFPLLMFAWKIAPALCCGN 205 YY +A ++ PV+ T+ + E P+ G + P+NF + APAL GN Sbjct: 171 YYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GN 228 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 TVV KP++ LS + +++EAG P GVIN +PG + + + FTGST Sbjct: 229 TVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGST 288 Query: 266 EV-----GKL---IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQG 317 V GK+ + E R + R+ E GGK+ +++ A++ +AV +G F QG Sbjct: 289 NVFKSLYGKIQSGVVEGKYR-DYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQG 347 Query: 318 QCCTAGSRIFVEESIYEEF------VRRSVERAKRRVVGSPFDPTTEQ---GPQIDKKQY 368 Q C+A SR+++ ES EEF + +S SP + GP I ++ + Sbjct: 348 QKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSF 407 Query: 369 NKILELIQSGVAEGAKLEC--GGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEIL 426 +K++++I+ + +LE GG+ +G+F+ PTV D E FGP+ + Sbjct: 408 DKLVKVIEDA-KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVY 466 Query: 427 -----RFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSS---AMQAGTVWIN--CYNA 476 F + ++I+ N S + L A+F D KA+ + AG +IN C A Sbjct: 467 EYPDTEFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGA 523 Query: 477 LNAQSPFGGFKMSGNGREMG 496 + +Q FGG +MSG + G Sbjct: 524 VVSQQWFGGARMSGTDDKAG 543 >3V9H-A nrPDB Length = 566 Score = 148 bits (373), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 124/454 (27%), Positives = 217/454 (47%), Gaps = 28/454 (6%) Query: 63 GEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLAT 122 G +V + ADK+ ++KA++AA A W ++R ++ K AD++ R Sbjct: 91 GHKVAKFCYADKSLLNKAIEAALAA---RKEWDLKPIADRAQIFLKAADMLSGPRRAEIL 147 Query: 123 MESLNG-GKPFLQAFYVDLQGVIKTFRYYAGWADKIHG---MTIPVDGDYFTFTRHEPIG 178 +++ G GK +QA +I FR+ A +A ++ G +++P + + E G Sbjct: 148 AKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--G 205 Query: 179 VCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINI 238 I P+NF + APAL GN V+ KP++ L++ + +++EAG PP +I Sbjct: 206 FVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQF 264 Query: 239 LPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS-----NLKRVTLELGGKSPN 293 +P GP G + S + I FTGS K + + ++ R+ E GGK+ + Sbjct: 265 VPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFH 324 Query: 294 IIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPF 353 + AD++ V + F GQ C+A +R++V S++ + R +E R VG P Sbjct: 325 FVHRSADVESVVSGTLRSAFEYGGQKCSACARLYVPHSLWPQIKGRLLEEHSRIKVGDPA 384 Query: 354 -DPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLGRKGFFIEPTVFSNVTDDM 411 D T ID K + +I + ++ + + + GGK G+F+EP + + Sbjct: 385 EDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQE 444 Query: 412 RIAKEEIFGPVQEIL-----RFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQ- 465 I KEEIFGPV + ++K ++++ + + +GL AVF+ D + + ++ Sbjct: 445 PIMKEEIFGPVLSVYVYPDDKYKETLQLVD--STTSYGLTGAVFSQDKDVVQEATKVLRN 502 Query: 466 -AGTVWIN--CYNALNAQSPFGGFKMSGNGREMG 496 AG +IN ++ Q PFGG + SG + G Sbjct: 503 AAGNFYINDKSTGSIVGQQPFGGARASGTNDKPG 536 >3SZA-A nrPDB Length = 469 Score = 146 bits (369), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 123/445 (27%), Positives = 205/445 (46%), Gaps = 22/445 (4%) Query: 75 ADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQ 134 + I +AV+ AR AFS G R R + L+ L L++ L + + K Sbjct: 18 SKISEAVKRARAAFSSG---RTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWN 74 Query: 135 AFYVDLQGVIKTFRYYAG----WADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPL 190 A+Y ++ V++ Y WA P + EP+GV I WN+P Sbjct: 75 AYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPF 134 Query: 191 LMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAI 250 + + A+ GN VV+KP+E + A + +I + + ++ G P + Sbjct: 135 NLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELL 193 Query: 251 ASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQ 310 D I +TGST VGK+I AA + +L VTLELGGKSP + + DLD A + Sbjct: 194 KERF--DHILYTGSTGVGKIIMTAAAK-HLTPVTLELGGKSPCYVDKNCDLDVACRRIAW 250 Query: 311 GVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNK 370 G F N GQ C A I + SI + V + ++++ + G + + G I + + + Sbjct: 251 GKFMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKEFYGEDAKKSRDYGRIISARHFQR 309 Query: 371 ILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT 430 ++ LI EG K+ GG G +I PT+ ++V + +EEIFGPV I+ ++ Sbjct: 310 VMGLI-----EGQKVAYGGTG-DAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRS 363 Query: 431 MDEVIERANNSDFGLVAAVFTND---INKALTVSSAMQAGTVWINCYNALNAQSPFGGFK 487 ++E I+ N + L +F+++ I K + +S+ + + L++ PFGG Sbjct: 364 LEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSL-PFGGVG 422 Query: 488 MSGNGREMGEFGLREYSEVKTVTVK 512 SG G G+ +S ++ V+ Sbjct: 423 NSGMGSYHGKKSFETFSHRRSCLVR 447 >4LGZ-A nrPDB Length = 563 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 126/451 (27%), Positives = 213/451 (47%), Gaps = 24/451 (5%) Query: 64 EQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATM 123 +V + ADKA +++A+ AA A W ++R ++ K AD++ R Sbjct: 89 HKVAKFCYADKALLNRAIDAALAA---RKEWDLKPMADRAQVFLKAADMLSGPRRAEVLA 145 Query: 124 ESLNG-GKPFLQAFYVDLQGVIKTFRYYAGWADKIHG---MTIPVDGDYFTFTRHEPIGV 179 +++ G GK +QA +I FR+ A +A ++ G +++P ++ + E G Sbjct: 146 KTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLE--GF 203 Query: 180 CGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINIL 239 I P+NF + APAL GN V+ KP++ L++ + +++EAG PP +I + Sbjct: 204 VAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFV 262 Query: 240 PGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS-----NLKRVTLELGGKSPNI 294 P GPT G + S + I FTGS K + ++ R+ E GGK+ + Sbjct: 263 PADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHF 322 Query: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPF- 353 + + AD+D V + F GQ C+A SR++V +S++ + R +E R VG P Sbjct: 323 VHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAE 382 Query: 354 DPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLGRKGFFIEPTVFSNVTDDMR 412 D T ID K + +I + ++ + + + GG+ G+++EP + + Sbjct: 383 DFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEP 442 Query: 413 IAKEEIFGPVQEILRF---KTMDEVIERANNSDFGLVAAVFTND--INKALTVSSAMQAG 467 I KEEIFGPV + + K + + + + +GL AVF D I + T AG Sbjct: 443 IMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAG 502 Query: 468 TVWIN--CYNALNAQSPFGGFKMSGNGREMG 496 +IN ++ Q PFGG + SG + G Sbjct: 503 NFYINDKSTGSVVGQQPFGGARASGTNDKPG 533 >1AD3-A nrPDB Length = 452 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 121/446 (27%), Positives = 205/446 (45%), Gaps = 28/446 (6%) Query: 77 IDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAF 136 I V+ AR AF+ G + R + L+ L ++ + ++ + + GK ++ Sbjct: 3 ISDTVKRAREAFNSG---KTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSY 59 Query: 137 YVDLQGVIK----TFRYYAGWA-DKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLL 191 Y ++ V++ T + WA D+ T D + EP+GV I WN+P Sbjct: 60 YEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDL-YIHSEPLGVVLVIGAWNYPFN 118 Query: 192 MFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIA 251 + + A+ GN V++KP+E + A + LI + + ++ G P + Sbjct: 119 LTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLK 177 Query: 252 SHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQG 311 D I +TGST VGK++ AA + +L VTLELGGKSP + D DLD A + G Sbjct: 178 ERF--DHIMYTGSTAVGKIVMAAAAK-HLTPVTLELGGKSPCYVDKDCDLDVACRRIAWG 234 Query: 312 VFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKI 371 F N GQ C A I + SI + V + ++++ + G + + G I+ + + ++ Sbjct: 235 KFMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKDFYGEDAKQSRDYGRIINDRHFQRV 293 Query: 372 LELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTM 431 G+ + K+ GG + +I PT+ +V + +EEIFGPV I+ +++ Sbjct: 294 -----KGLIDNQKVAHGGT-WDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSL 347 Query: 432 DEVIERANNSDFGLVAAVFTND---INKAL--TVSSAMQAGTVWINCYNALNAQSPFGGF 486 +E I+ N + L VF+N+ I K + T S + A V ++ PFGG Sbjct: 348 EEAIQFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHI---TVPTLPFGGV 404 Query: 487 KMSGNGREMGEFGLREYSEVKTVTVK 512 SG G G+ +S ++ VK Sbjct: 405 GNSGMGAYHGKKSFETFSHRRSCLVK 430 >4QGK-A nrPDB Length = 461 Score = 134 bits (336), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 105/345 (30%), Positives = 162/345 (46%), Gaps = 15/345 (4%) Query: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 230 + + +P+GV I WN+P ++ + A+ GN V+IKP+E + +A + L+ + Sbjct: 97 YIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYL 156 Query: 231 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 290 I I G T D I +TG+T VGK++ EAA + +L VTLELGGK Sbjct: 157 DQDLYIVINGGVEETTELLKQR---FDHIFYTGNTAVGKIVMEAAAK-HLTPVTLELGGK 212 Query: 291 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG 350 SP I D DLD + G + N GQ C A I E S+ + V + E K G Sbjct: 213 SPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVK-EFYG 271 Query: 351 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDD 410 + + I+ + + +IL L+ EG K+ GG+ +I PTV ++V Sbjct: 272 ENIKESPDYERIINLRHFKRILSLL-----EGQKIAFGGET-DEATRYIAPTVLTDVDPK 325 Query: 411 MRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVW 470 ++ +EEIFGP+ I+ K +DE I N + L VF+++ + +G V Sbjct: 326 TKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGVT 385 Query: 471 IN---CYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 N + LN+ PFGG SG G G+ +S + +K Sbjct: 386 GNDVIMHFTLNS-FPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLK 429 >4IDS-A nrPDB Length = 563 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 122/440 (27%), Positives = 195/440 (44%), Gaps = 29/440 (6%) Query: 92 SVWRRMDASERGRLLDKLADLVE---RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFR 148 S W + ER + + ADL+ R++ ATM L K QA + +I +R Sbjct: 113 SDWAALPFDERAAVFLRAADLLAGPWREKIAAATM--LGQSKSVYQAEIDAVCELIDFWR 170 Query: 149 YYAGWADKI-HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTV 207 + +A +I I G++ G I P+NF + APAL GNTV Sbjct: 171 FNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALM-GNTV 229 Query: 208 VIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEV 267 + KP+ L+A L++ AG PPGVIN++ G G + + I FTGST Sbjct: 230 IWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTAT 289 Query: 268 -GKLIQEAA---GR-SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTA 322 G L Q GR + R+ E GGK + A A D +G F QGQ C+A Sbjct: 290 FGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSA 349 Query: 323 GSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEG 382 SR F+ S+++ + +A G D + G ID++ + K ++ I+ Sbjct: 350 VSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAA 409 Query: 383 A-KLECGGKGLGRKGFFIEPTVF--SNVTDDMRIAKEEIFGPVQEIL-----RFKTMDEV 434 A + GG+ +G+F+ PTV + TD+ + E FGP+ + R++ + +V Sbjct: 410 AVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVI--EYFGPLLSVHVYPDERYEQILDV 467 Query: 435 IERANNSDFGLVAAVFTNDINKALTVSSAMQ--AGTVWIN--CYNALNAQSPFGGFKMSG 490 I+ S + L AV +D LT ++ AG ++N A+ + PFGG + S Sbjct: 468 ID--TGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSD 525 Query: 491 NGREMGE-FGLREYSEVKTV 509 + G L ++ +++ Sbjct: 526 TNDKAGSPLNLLRWTSARSI 545 >5NNO-A nrPDB Length = 546 Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 99/358 (27%), Positives = 168/358 (46%), Gaps = 33/358 (9%) Query: 173 RHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFP 232 ++EP+GV I WN+PLL+ + AL GNT VIKP+E P +A + L+ + Sbjct: 114 QYEPLGVVLVIGTWNYPLLLILQPLLGALAAGNTAVIKPSELAPATAELLTKLLPKY-VS 172 Query: 233 PGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSP 292 V+ I+ G A + D I +TGS V +++ AA + +L VTLELGGKSP Sbjct: 173 SDVVGIVNGGVSETTAVLKER--FDHILYTGSARVAEIVMAAAAK-HLTPVTLELGGKSP 229 Query: 293 NII---FADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVV 349 ++ AD ++ E+ G N GQ A + VE+S+ E + ++ A++ ++ Sbjct: 230 VVVDDTCAD-NMKVVAERIMWGKIINAGQTSIAPDYVVVEKSM-ESVLVDALAEARKAML 287 Query: 350 GSPF------DPTTEQGPQ----------IDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 G F + +Q Q ++ + +++E ++ G K+ GG+ Sbjct: 288 GDKFLKVLKGELLVKQKQQFLEESDYPRIVNASHFQRLMEFMK-----GGKVAVGGEA-D 341 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 I PT+ +N+ + +EEIFGP+ +L ++ ++++ N+ + L VF+N+ Sbjct: 342 EATLTIAPTILTNIDPTHPVMQEEIFGPILPVLTYENEKDILKIINSREKPLALYVFSNN 401 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQS--PFGGFKMSGNGREMGEFGLREYSEVKTV 509 V S +G V +N PFGG SG G G + +S + V Sbjct: 402 KRFIRGVESRTSSGAVVVNDVVVHAGADGLPFGGVGRSGMGAYHGRYSFETFSHRRPV 459 >2Y53-A nrPDB Length = 534 Score = 84.7 bits (208), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 107/449 (23%), Positives = 186/449 (41%), Gaps = 44/449 (9%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K + +W + +G + +P TG + V ++ D+ +A AR G+ R + Sbjct: 9 KNHVAGQWI-AGTGAGITLTDPVTGVALVRV-SSEGLDLARAFSFAR--EDGGAALRALT 64 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ++R L + L++ R + + N G + VD+ G I T YYA + Sbjct: 65 YAQRAARLADIVKLLQAKRGDYYAIATANSGTTRNDS-AVDIDGGIFTLSYYAKLGASLG 123 Query: 159 GMTIPVDGDYFTFTRHEPI----------GVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 + DG + ++ GV I +NFP K APAL G V+ Sbjct: 124 EVHALRDGSAESLSKDRSFSAQHVLSPTRGVALFINAFNFPSWGLWEKAAPALLSGVPVI 183 Query: 209 IKPAEQTPLSALYMGALIKEAG-FPPGVINILPGYGPTAGAAIASHI-GIDKIAFTGSTE 266 +KPA T M A + +AG PPG ++I+ G + A + I D ++FTGS + Sbjct: 184 VKPATATAWLTQRMVADVVDAGILPPGALSIICG----SSAGLLDQIRSFDVVSFTGSAD 239 Query: 267 VGKLIQ-EAAGRSNLKRVTLELGGKSPNIIFADAD-----LDYAVEQAHQGVFFNQGQCC 320 ++ A R+ ++ + I+ ADA D +++ + + GQ C Sbjct: 240 TAATLRAHPAFVQRGARLNVQADSLNSAILCADATPDTPAFDLFIKEVVREMTVKSGQKC 299 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 TA R FV E+ E + + + VG+P + G + ++QY +L I + + Sbjct: 300 TAIRRAFVPEAALEPVLEALKAKLAKITVGNPRNDAVRMGSLVSREQYENVLAGI-AALR 358 Query: 381 EGAKLECGGKGL------GRKGFFIEPTVF-SNVTDDMRIAKE-EIFGPVQEILRFK-TM 431 E A L + + P +F N D+ + + E+FGPV + ++ T Sbjct: 359 EEAVLAYDSSAVPLIDADANIAACVAPHLFVVNDPDNATLLHDVEVFGPVASVAPYRVTT 418 Query: 432 D-------EVIERANNSDFGLVAAVFTND 453 D + A LVA++++ND Sbjct: 419 DTNALPEAHAVALARRGQGSLVASIYSND 447 >6D97-A nrPDB Length = 547 Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 71/298 (23%), Positives = 125/298 (41%), Gaps = 35/298 (11%) Query: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 P G I P+NFPL + ++ AL GN V+K + + M L+ + G P Sbjct: 188 PYGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHDCGLPAED 247 Query: 236 INILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-KLIQEAAGRSNLKRVTLELGGKSPNI 294 ++ + G + FTGS+ V KL + GR L+ + P++ Sbjct: 248 MDFINSDGAVMNKLLL-EANPKMTLFTGSSRVAEKLAADLKGRVKLEDAGFDWKILGPDV 306 Query: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE----EFVRRSVERAKRR--V 348 ++DY Q + GQ C+A S +F+ ++ E +++ ER K Sbjct: 307 ----QEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKKLSERRKLEDLT 362 Query: 349 VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF-----FIEPT- 402 +G TTE + N +L++ G+K+ GG+ L ++PT Sbjct: 363 IGPVLTVTTEAMIE----HMNNLLKI------RGSKVLFGGEPLANHSIPKIYGAMKPTA 412 Query: 403 VFSNVTDDMR-----IAKEEIFGPVQEILRFK--TMDEVIERANNSDFGLVAAVFTND 453 VF + + ++ + +EIFGP Q + + ++ V+E + L AA+ +ND Sbjct: 413 VFVPLEEILKSGNFELVTKEIFGPFQVVTEYSEDQLELVLEACERMNAHLTAAIVSND 470 >5UJU-A nrPDB Length = 576 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 49/156 (31%), Positives = 71/156 (45%), Gaps = 16/156 (10%) Query: 180 CGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT--PLSALYMGA--LIKEAGFPPGV 235 C WN +FA L GNTV++KP PL+ A +++EAGF P V Sbjct: 213 CCTFPTWNGYPGLFA-----DLATGNTVIVKPHPGAILPLAITVRIARDVLREAGFDPNV 267 Query: 236 INILPGYGPTAGAAI---ASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSP 292 + +L P GA + A I I FTGST+ G ++ A ++ +V E G + Sbjct: 268 VTLL-ATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQA---QVYTEKAGVNQ 323 Query: 293 NIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 +I + DL A + + GQ CTA I+V Sbjct: 324 IVIDSTDDLKAAAKNIAFSLALYSGQMCTAPQNIYV 359 >3V4C-A nrPDB Length = 528 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 109/463 (23%), Positives = 171/463 (36%), Gaps = 47/463 (10%) Query: 39 KIFINNEW-QNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAF-SLGSVWRR 96 K + EW + + P + PA V V+ +++A +AA AF + G R+ Sbjct: 31 KHLVAGEWLDGAGTFASAPAHGPAHDFAVGTVEL-----VNRACEAAEEAFWTYGYSSRK 85 Query: 97 MDASERGRLLDKLADLVERDRAVLATMESLNGGKP--FLQAFYVDLQGVIKTFRYYAGWA 154 ER L +AD +E + + S G P L G ++ F + Sbjct: 86 ----ERAAFLRAIADEIEARAEAITEIGSQETGLPEARLNGERGRTTGQLRLFADHIEKG 141 Query: 155 DKIHGMTIPVDGDYFTFTRHE------PIGVCGQIIPWNFPLLM--FAWKIAPALCCGNT 206 D + + R E P+G NFPL A AL G Sbjct: 142 DYLDRRVDAAMPERQPAPRQEIRLVQRPVGPVAVFGASNFPLAFSTAGGDTAAALAAGCP 201 Query: 207 VVIKPAEQTP----LSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFT 262 VV+K P + A + A I++ G PGV +++ G G A+ H I + FT Sbjct: 202 VVVKGHSAHPGTGEIVAEAVDAAIRKTGVHPGVFSLIQGGSRDVGHALVQHPHIKAVGFT 261 Query: 263 GSTEVGK-LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQG----VFFNQG 317 GS G+ L A R ELG +P + +A L E QG + G Sbjct: 262 GSLAGGRALFDLCAARPEPIPFFGELGSVNPMFLLPEA-LKARAETLGQGWAGSLTMGAG 320 Query: 318 QCCT-AGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILEL-I 375 Q CT G + +E + + F +VE + P T I K + Sbjct: 321 QFCTNPGIAVVIEGADADRFTTAAVEALAK------VAPQTMLTDGIAKAYRDGQARFAT 374 Query: 376 QSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVI 435 ++ V E G+ F T + D + EE+FGP+ ++R + E+ Sbjct: 375 RNAVKPLLATESSGRDASPNLF---ETTGAQFLADHALG-EEVFGPLGLVVRVGSPAEME 430 Query: 436 ERANNSDFGLVAAVFTN--DINKALTVSSAMQ--AGTVWINCY 474 E A L A + + D+ A + ++ AG V +N + Sbjct: 431 ELARGFQGQLTATIHMDAGDLETARRLRPVLERKAGRVLVNGF 473 >5DBV-A nrPDB Length = 445 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 80/333 (24%), Positives = 128/333 (38%), Gaps = 42/333 (12%) Query: 169 FTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKE 228 T P GV G I P P L GNTVV P ++ + LI E Sbjct: 102 LTLVEMGPFGVIGAITPCTNPSETIICNTIGMLAGGNTVVFNPHPAAIKTSNFAVQLINE 161 Query: 229 AGFPP-GVINILPGY-GPTAGAA--IASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVT 284 A G +NI PT ++ + SH I IA TG V + ++ KR Sbjct: 162 ASLSAGGPVNIACSVRKPTLDSSKIMMSHQDIPLIAATGGPGVVTAVLQSG-----KRGI 216 Query: 285 LELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERA 344 G P ++ AD+ A E G F+ A + ++I E + V+ Sbjct: 217 GAGAGNPPVLVDETADIRKAAEDIINGCTFDNNLPAIAEKEVVAIDAIANELMNYMVK-- 274 Query: 345 KRRVVGSPFDPTTEQGP-QIDKKQYNKILELIQSGVAEGAKLECGGKG----LGRKGFFI 399 EQG I K+Q K+ L+ + +G C GK LG G + Sbjct: 275 -------------EQGCYAITKEQQEKLTNLVIT--PKGLNRNCVGKDARTLLGMIGIDV 319 Query: 400 EPTVFSNVTDDMR---IAKEEIFGPVQEILRFKTMDEVIERANNSDFG--LVAAVFTNDI 454 + + + + + EE+ P+ I+R K+ D+ +E+A + G A + + ++ Sbjct: 320 PSNIRCIIFEGEKEHPLISEELMMPILGIVRAKSFDDAVEKAVWLEHGNRHSAHIHSKNV 379 Query: 455 NKALTVSSAMQAGTVWINC--YNALNAQSPFGG 485 ++ T + A+ + N Y A+ FGG Sbjct: 380 DRITTYAKAIDTAILVKNAPSYAAIG----FGG 408 >5J7I-A nrPDB Length = 488 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 66/271 (24%), Positives = 106/271 (39%), Gaps = 16/271 (5%) Query: 76 DID-KAVQAAR----LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGK 130 DID +++Q R A + + +M SE ++++ +A+ + LA M G Sbjct: 27 DIDLQSIQEVRNYLEEAKAAQKILEKMTQSEIDKIVESMANAAREEAGRLAAMAVEETG- 85 Query: 131 PFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPL 190 F L+ + Y D I D + + +P+G+ IIP P Sbjct: 86 -FGNVEDKTLKNLFAANDVYNSIKDVKTVGIIRRDEENRVWEIAQPVGIVAGIIPSTNPT 144 Query: 191 LMFAWKIAPALCCGNTVVIKP----AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTA 246 +K A+ N +V P A+ T +A M + AG P G+I+ + A Sbjct: 145 STVIFKALIAVKARNAIVFSPHPSAAKCTAEAARIMQEAAERAGAPKGLISCITQPTMAA 204 Query: 247 GAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVE 306 + H D I TG + K A S+ K G P I A++ AV+ Sbjct: 205 TNELMKHKLTDVILATGGPGLVK-----AAYSSGKPAYGVGPGNVPVYIHESANIAKAVQ 259 Query: 307 QAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 Q F+ G C + + V+ESI E+ V Sbjct: 260 LIIQSKTFDYGTICASEQALLVDESIKEKVV 290 >1EZ0-A nrPDB Length = 510 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 68/259 (26%), Positives = 100/259 (38%), Gaps = 33/259 (12%) Query: 94 WRRMDASERGRLLDKLA--------DLVERDRAVLATMESLNGGKPFLQAFYVDL-QGVI 144 +RR++ S+R LL +A D++ R A E G+ A + L V+ Sbjct: 46 FRRLNNSKRASLLRTIASELEARSDDIIARAHLETALPEVRLTGEIARTANQLRLFADVV 105 Query: 145 KTFRYYAGWADKIHGMTIPVDGDYFTFTRHE----PIGVCGQIIPWNFPLLMFAW--KIA 198 + Y+ D + P+ R + P+ V G NFPL A A Sbjct: 106 NSGSYHQAILDTPNPTRAPLPKP--DIRRQQIALGPVAVFGA---SNFPLAFSAAGGDTA 160 Query: 199 PALCCGNTVVIKPAEQTPLSALYMGALIKEA----GFPPGVINILPGYGPTAGAAIASHI 254 AL G V++K P ++ + I++A P + +L G G A+ SH Sbjct: 161 SALAAGCPVIVKGHTAHPGTSQIVAECIEQALKQEQLPQAIFTLLQGNQRALGQALVSHP 220 Query: 255 GIDKIAFTGSTEVGK-LIQEAAGRSNLKRVTLELGGKSPNIIF-----ADADLDYAVEQA 308 I + FTGS G+ L A R ELG +P IF A ADL +Q Sbjct: 221 EIKAVGFTGSVGGGRALFNLAHERPEPIPFYGELGAINPTFIFPSAMRAKADL---ADQF 277 Query: 309 HQGVFFNQGQCCTAGSRIF 327 + GQ CT +F Sbjct: 278 VASMTMGCGQFCTKPGVVF 296 >3MY7-A nrPDB Length = 452 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 9/179 (5%) Query: 165 DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGA 224 D + T T EP+G+ I+P P +K +L N ++ P + S Sbjct: 92 DDNLGTMTIAEPVGIICGIVPTTNPTSTAIFKSLISLKTRNGIIFSPHPRAKNSTNDAAK 151 Query: 225 LIKEA----GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNL 280 L+ +A G P +I + A+ H I I TG + K A S+ Sbjct: 152 LVLDAAVAAGAPKDIIGWIDQPSVELSNALMKHDDIALILATGGPGMVK-----AAYSSG 206 Query: 281 KRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 K G P +I AD+ AV F+ G C + + V + +Y+E R Sbjct: 207 KPAIGVGAGNVPVVIDETADIKRAVASVLMSKTFDNGVVCASEQAVIVVDEVYDEVKER 265 >5JFN-A nrPDB Length = 524 Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust. Identities = 62/310 (20%), Positives = 111/310 (35%), Gaps = 33/310 (10%) Query: 169 FTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKE 228 T + P GV G I P P L GN+VV P + +L + LI + Sbjct: 180 LTLVEYSPFGVIGAITPTTNPTETIVCNSIGMLAAGNSVVFSPHPRARQVSLLLVRLINQ 239 Query: 229 A----GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVT 284 G P ++ + A+ +H + + TG + K + S K+ Sbjct: 240 KLAALGAPENLVVTVEKPSIENTNAMMAHPKVRMLVATGGPAIVKAV-----LSTGKKAI 294 Query: 285 LELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERA 344 G P ++ A+++ A G F+ A I I + + + Sbjct: 295 GAGAGNPPVVVDETANIEKAACDIVNGCSFDNNLPXVAEKEIIAVAQIADYLIFNLKKNG 354 Query: 345 KRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG----LGRKGFFIE 400 + DP Q Q L L G G + +C GK L + G ++ Sbjct: 355 AYEI----KDPAVLQQLQ--------DLVLTAKG---GPQTKCVGKSAVWLLSQIGISVD 399 Query: 401 PT---VFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERA--NNSDFGLVAAVFTNDIN 455 + + V + +EE+ P+ ++R +T+D+ I+ A D A + + D+ Sbjct: 400 ASIKIILMEVPREHPFVQEELMMPILPLVRVETVDDAIDLAIEVEHDNRHTAIMHSTDVR 459 Query: 456 KALTVSSAMQ 465 K ++ +Q Sbjct: 460 KLTKMAKLIQ 469 >3K9D-A nrPDB Length = 464 Score = 36.2 bits (82), Expect = 0.035, Method: Compositional matrix adjust. Identities = 41/172 (23%), Positives = 67/172 (38%), Gaps = 13/172 (7%) Query: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKE----AGF 231 P+GV +IP P +K ++ GN++V P + L +I E AG Sbjct: 108 PLGVVAGLIPSTNPTSTVIYKTLISIKAGNSIVFSPHPNALKAILETVRIISEAAEKAGC 167 Query: 232 PPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKS 291 P G I+ + + H I TG G + +AA S + + G Sbjct: 168 PKGAISCMTVPTIQGTDQLMKHKDTAVILATG----GSAMVKAAYSSGTPAIGVG-PGNG 222 Query: 292 PNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE----ESIYEEFVRR 339 P I A++ AV+ F+ G C + + VE E++ EF ++ Sbjct: 223 PAFIERSANIPRAVKHILDSKTFDNGTICASEQSVVVERVNKEAVIAEFRKQ 274 >3IP1-A nrPDB Length = 404 Score = 32.0 bits (71), Expect = 0.73, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 10/90 (11%) Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIA--SHIGIDKIAFTGSTEVGKLIQE 273 P S Y +++ G PG ++ G GP AA+A H G K+ + +EV + + + Sbjct: 196 PTSVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAK 255 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDY 303 G ++ T E F +A LDY Sbjct: 256 ELGADHVIDPTKE--------NFVEAVLDY 277 >1WKO-A nrPDB Length = 180 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 9/64 (14%) Query: 347 RVVGSPFD---PTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFF----I 399 RVVG D PTT+ +KKQ + EL S V+ ++E G L + FF I Sbjct: 19 RVVGDVLDFFTPTTKMNVSYNKKQVSNGHELFPSSVSSKPRVEIHGGDL--RSFFTLVMI 76 Query: 400 EPTV 403 +P V Sbjct: 77 DPDV 80 >2AW5-A nrPDB Length = 575 Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust. Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 12/132 (9%) Query: 350 GSPFDPTT-EQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVT 408 GSPFDP T G + Q N + GVA G + CG + + F V + Sbjct: 444 GSPFDPVTLPNGQTLYPGQGNN--SYVFPGVALGV-VACGLRQITDNIFLTTAEVIAQQV 500 Query: 409 DDMRIAKEEIFGPVQEI--LRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQA 466 D + + ++ P+ I + K +++++ A A V+ NK V S M + Sbjct: 501 SDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEK---TATVYPEPQNKEAFVRSQMYS 557 Query: 467 ---GTVWINCYN 475 + +CY+ Sbjct: 558 TDYDQILPDCYS 569 >2CBU-A nrPDB Length = 468 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 7/100 (7%) Query: 57 VYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERD 116 V N TG+ C+ K DI+ + A+ W R+ GR+ K D R Sbjct: 67 VKNGDTGDVACDHYNRWKEDIEIIEKLGVKAYRFSISWPRILPEGTGRVNQKGLDFYNR- 125 Query: 117 RAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADK 156 ++ T+ G PF+ ++ DL ++ GWA++ Sbjct: 126 --IIDTLLE-KGITPFVTIYHWDLPFALQL---KGGWANR 159 >1TF2-A nrPDB Length = 844 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 55/247 (22%), Positives = 92/247 (37%), Gaps = 49/247 (19%) Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLM------------- 192 TF+ Y +K+ GMT + F + V IP N P++ Sbjct: 359 TFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVV--TIPTNRPVVRDDRPDLIYRTMEG 416 Query: 193 ----FAWKIAPALCCGNTVVIKPA--EQTPLSALYMGALIKEAGFPPGVIN--------- 237 A +A G V++ E + L + L+K G P V+N Sbjct: 417 KFKAVAEDVAQRYMTGQPVLVGTVAVETSEL----ISKLLKNKGIPHQVLNAKNHEREAQ 472 Query: 238 ILPGYGPTAGAAIASHI---GIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKS--- 291 I+ G IA+++ G D G E+G L R +R+ +L G+S Sbjct: 473 IIEEAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQ 532 Query: 292 --PNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES--IYEEFVRRSVERAKRR 347 P I ++ + + F + R +++S I + V R+VE +++R Sbjct: 533 GDPGITQFYLSMEDELMRR-----FGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKR 587 Query: 348 VVGSPFD 354 V G+ FD Sbjct: 588 VEGNNFD 594 >5EUL-A nrPDB Length = 836 Score = 28.1 bits (61), Expect = 10.0, Method: Compositional matrix adjust. Identities = 57/249 (22%), Positives = 93/249 (37%), Gaps = 51/249 (20%) Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLM------------- 192 TF+ Y +K+ GMT + F + V IP N P++ Sbjct: 356 TFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVV--TIPTNRPVVRDDRPDLIYRTMEG 413 Query: 193 ----FAWKIAPALCCGNTVVIKPA--EQTPLSALYMGALIKEAGFPPGVIN--------- 237 A +A G V++ E + L + L+K G P V+N Sbjct: 414 KFKAVAEDVAQRYMTGQPVLVGTVAVETSEL----ISKLLKNKGIPHQVLNAKNHEREAQ 469 Query: 238 ILPGYGPTAGAAIASHI---GIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKS--- 291 I+ G IA+++ G D G E+G L R +R+ +L G+S Sbjct: 470 IIEEAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQ 529 Query: 292 --PNII-FADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES--IYEEFVRRSVERAKR 346 P I F + D + + F + R +++S I + V R+VE +++ Sbjct: 530 GDPGITQFYLSMEDELMRR------FGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQK 583 Query: 347 RVVGSPFDP 355 RV G+ FD Sbjct: 584 RVEGNNFDS 592 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4X2Q-A nrPDB 748 0.0 5AC0-A nrPDB 735 0.0 5AC2-A nrPDB 732 0.0 5FHZ-A nrPDB 705 0.0 1O9J-A nrPDB 703 0.0 5L13-A nrPDB 703 0.0 1AG8-A nrPDB 700 0.0 5GT6-A nrPDB 636 0.0 4PXL-B nrPDB 627 e-180 4PZ2-A nrPDB 620 e-178 4V3F-A nrPDB 616 e-177 4O6R-A nrPDB 607 e-174 4CAZ-A nrPDB 605 e-173 3RHO-A nrPDB 595 e-170 3IWK-A nrPDB 586 e-167 3IWJ-A nrPDB 584 e-167 4GO4-A nrPDB 584 e-167 4MPY-A nrPDB 579 e-165 3JZ4-A nrPDB 576 e-164 1BPW-A nrPDB 574 e-164 6QAO-A nrPDB 571 e-163 6B4R-B nrPDB 570 e-163 4QYJ-A nrPDB 570 e-163 4I8Q-A nrPDB 567 e-162 5IUV-A nrPDB 567 e-162 4I8P-A nrPDB 566 e-162 4O5H-A nrPDB 562 e-160 2D4E-A nrPDB 561 e-160 3R31-A nrPDB 557 e-159 4V6H-A nrPDB 539 e-154 5KLK-A nrPDB 539 e-153 5J77-A nrPDB 537 e-153 1WNB-A nrPDB 533 e-152 6C43-A nrPDB 528 e-150 3I44-A nrPDB 527 e-150 3TY7-A nrPDB 527 e-150 3U4J-A nrPDB 526 e-149 3EK1-A nrPDB 523 e-149 4LIH-A nrPDB 522 e-148 4U3W-A nrPDB 521 e-148 3K2W-A nrPDB 516 e-147 2HG2-A nrPDB 515 e-146 4F3X-A nrPDB 514 e-146 1T90-A nrPDB 507 e-144 5EUY-A nrPDB 503 e-143 3QAN-A nrPDB 502 e-142 5X5U-A nrPDB 501 e-142 3B4W-A nrPDB 500 e-142 3RJL-A nrPDB 494 e-140 4JZ6-A nrPDB 492 e-139 2JG7-A nrPDB 492 e-139 2W8P-A nrPDB 492 e-139 4YWE-A nrPDB 490 e-139 3RHD-A nrPDB 490 e-139 5VBF-A nrPDB 489 e-138 5UR2-A nrPDB 489 e-138 3RH9-A nrPDB 488 e-138 5TJR-A nrPDB 487 e-138 4X0T-A nrPDB 484 e-137 4DNG-A nrPDB 477 e-135 4ZZ7-A nrPDB 476 e-135 3R64-A nrPDB 471 e-133 2QE0-A nrPDB 471 e-133 4PXN-A nrPDB 470 e-133 3PRL-A nrPDB 465 e-131 3VZ3-A nrPDB 463 e-130 6MVR-A nrPDB 462 e-130 6FK3-A nrPDB 462 e-130 3EFV-A nrPDB 454 e-128 3VZ0-A nrPDB 452 e-127 4OGD-A nrPDB 449 e-126 3ROS-A nrPDB 448 e-126 2J5N-A nrPDB 445 e-125 5N5S-A nrPDB 444 e-125 4E4G-A nrPDB 443 e-125 5U0M-A nrPDB 437 e-123 5KF0-A nrPDB 435 e-122 5JRY-A nrPDB 430 e-121 5J6B-A nrPDB 424 e-119 1UXV-A nrPDB 422 e-118 6DBB-A nrPDB 418 e-117 3SZA-A nrPDB 416 e-116 4KNA-A nrPDB 411 e-115 3JU8-A nrPDB 408 e-114 4I3V-A nrPDB 406 e-113 1AD3-A nrPDB 398 e-111 3V9H-A nrPDB 395 e-110 4LGZ-A nrPDB 393 e-110 4QGK-A nrPDB 373 e-104 4OE4-A nrPDB 366 e-101 5UCD-A nrPDB 364 e-101 4H7N-A nrPDB 354 6e-98 4IDS-A nrPDB 334 8e-92 5NNO-A nrPDB 310 9e-85 2Y53-A nrPDB 265 3e-71 3V4C-A nrPDB 253 1e-67 5DBV-A nrPDB 223 2e-58 6D97-A nrPDB 211 7e-55 1EZ0-A nrPDB 196 2e-50 5J7I-A nrPDB 193 1e-49 5UJU-A nrPDB 153 2e-37 Sequences not found previously or not previously below threshold: 5JFN-A nrPDB 157 1e-38 3MY7-A nrPDB 155 3e-38 3K9D-A nrPDB 151 7e-37 1O20-A nrPDB 112 4e-25 4GHK-A nrPDB 99 2e-21 1VLU-A nrPDB 81 9e-16 4JBE-A nrPDB 78 1e-14 2H5G-A nrPDB 73 3e-13 3AGK-A nrPDB 34 0.19 3DOD-A nrPDB 32 0.58 5UPP-A nrPDB 31 0.93 3Q09-A nrPDB 31 0.96 4Q1V-A nrPDB 31 1.4 6AHD-9 nrPDB 31 1.5 4G9Q-A nrPDB 31 1.5 4U83-A nrPDB 31 1.5 4N4Q-A nrPDB 31 1.9 1NNE-A nrPDB 30 2.0 5WYK-3D nrPDB 30 2.1 1EWR-A nrPDB 30 2.2 3LOO-A nrPDB 30 2.5 1V9N-A nrPDB 30 2.6 4WJB-A nrPDB 30 2.8 2CUN-A nrPDB 30 2.8 3UF0-A nrPDB 29 3.7 6D6K-A nrPDB 29 4.9 1J3N-A nrPDB 29 4.9 3HOA-A nrPDB 29 5.5 3C3E-A nrPDB 29 5.9 4WHB-E nrPDB 29 6.6 3HSK-A nrPDB 28 8.6 4G09-A nrPDB 28 8.8 3A2Q-A nrPDB 28 9.4 2IPH-A nrPDB 28 9.9 >4X2Q-A nrPDB Length = 504 Score = 748 bits (1931), Expect = 0.0, Method: Composition-based stats. Identities = 498/498 (100%), Positives = 498/498 (100%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA Sbjct: 7 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 66 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL Sbjct: 67 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 126 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA Sbjct: 127 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 186 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA Sbjct: 187 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 246 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC Sbjct: 247 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 306 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA Sbjct: 307 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 366 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN Sbjct: 367 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 426 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL Sbjct: 427 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 486 Query: 501 REYSEVKTVTVKIPQKNS 518 REYSEVKTVTVKIPQKNS Sbjct: 487 REYSEVKTVTVKIPQKNS 504 >5AC0-A nrPDB Length = 501 Score = 735 bits (1897), Expect = 0.0, Method: Composition-based stats. Identities = 365/498 (73%), Positives = 441/498 (88%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 +++ +P+P NL+ KYTKIFINNEW +S SG+ FPV+NPAT E++CEV+E DK D+DKA Sbjct: 4 SAMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKA 63 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V+AAR AF +GS WR MDASERGRLL+KLADL+ERDR +LATME++NGGK F A+ +DL Sbjct: 64 VKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDL 123 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 G IKT RY AGWADKI G TIP+DG++FT+TR EP+GVCGQIIPWNFPLLMF WKI PA Sbjct: 124 GGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPA 183 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 L CGNTVV+KPAEQTPL+AL+MG+LIKEAGFPPGV+NI+PGYGPTAGAAI+SH+ +DK+A Sbjct: 184 LSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVA 243 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTEVGKLI+EAAG+SNLKRV+LELGGKSP I+FADADLD AVE AHQGVF++QGQCC Sbjct: 244 FTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCC 303 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 A SR+FVEESIY+EFVRRSVERAK+ V+G+P P QGPQIDK+QY KIL+LI+SG Sbjct: 304 IAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKK 363 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EGAKLECGG G KG+FI+PTVFS+VTDDMRIAKEEIFGPVQ+I++FK++D+VI+RANN Sbjct: 364 EGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANN 423 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 + +GL A +FTNDI+KA+TVSSA+Q+GTVW+NCY+ ++AQ PFGGFKMSGNGRE+GE+G Sbjct: 424 TFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGF 483 Query: 501 REYSEVKTVTVKIPQKNS 518 EY+EVKTVT+KI QKNS Sbjct: 484 HEYTEVKTVTIKISQKNS 501 >5AC2-A nrPDB Length = 501 Score = 732 bits (1889), Expect = 0.0, Method: Composition-based stats. Identities = 361/493 (73%), Positives = 431/493 (87%) Query: 26 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 LP +L+I+YTKIFINNEW +S SG+ FPV+NPAT E++C+V+E DK D+DKAV+AAR Sbjct: 9 LPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAAR 68 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 AF +GS WR MDASERGRLL KLADL+ERDR +LATMES+NGGK + A+ DL G IK Sbjct: 69 QAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIK 128 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 T RY AGWADKI G TIP+DG++FT+TRHEPIGVCGQIIPWNFPL+M WKI PAL CGN Sbjct: 129 TLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGN 188 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 TVV+KPAEQTPL+AL++ +LIKEAGFPPGV+NI+PGYGPTAGAAI+SH+ IDK+AFTGST Sbjct: 189 TVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGST 248 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 EVGKLI+EAAG+SNLKRVTLELGGKSP I+ ADADLD AVE AH GVF++QGQCC A SR Sbjct: 249 EVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASR 308 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 IFVEESIY+EFVRRSVERAK+ ++G+P P QGPQIDK+QY+KIL+LI+SG EGAKL Sbjct: 309 IFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKL 368 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 ECGG G KG+F++PTVFSNVTD+MRIAKEEIFGPVQ+I++FK++D+VI+RANN+ +GL Sbjct: 369 ECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGL 428 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 A VFT DI+KA+T+SSA+QAGTVW+NCY ++AQ PFGGFKMSGNGRE+GE+G EY+E Sbjct: 429 SAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTE 488 Query: 506 VKTVTVKIPQKNS 518 VKTVTVKI QKNS Sbjct: 489 VKTVTVKISQKNS 501 >5FHZ-A nrPDB Length = 529 Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats. Identities = 354/493 (71%), Positives = 424/493 (86%) Query: 25 LLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAA 84 LP P NLE+K+TKIFINNEW S+SG+ F NP+T EQ+CEV+E DK D+DKAV+AA Sbjct: 36 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 95 Query: 85 RLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVI 144 ++AF GS WRR+DA RGRLL +LADLVERDRA LA +E+++ GKPFL AF++DL+G I Sbjct: 96 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 155 Query: 145 KTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCG 204 +T RY+AGWADKI G TIP D + FTRHEPIGVCG I PWNFPLLM WK+APALCCG Sbjct: 156 RTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCG 215 Query: 205 NTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGS 264 NT+V+KPAEQTPL+ALY+G+LIKEAGFPPGV+NI+PG+GPT GAAI+SH I+KIAFTGS Sbjct: 216 NTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 275 Query: 265 TEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS 324 TEVGKL++EAA RSNLKRVTLELGGK+P I+ ADADLD AVE AHQGVFFNQGQCCTA S Sbjct: 276 TEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS 335 Query: 325 RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 R+FVEE +Y EFVRRSVE AK+R VG PFD TEQGPQID+KQ++KILELI+SG EGAK Sbjct: 336 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 395 Query: 385 LECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG 444 LECGG + KG FI+PTVFS VTD+MRIAKEEIFGPVQ IL+FK+++EVI+RAN++D+G Sbjct: 396 LECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG 455 Query: 445 LVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYS 504 L AAVFT +++KAL ++SA+++GTVWINCYNAL AQ+PFGGFKMSGNGRE+GE+ L EY+ Sbjct: 456 LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYT 515 Query: 505 EVKTVTVKIPQKN 517 EVKTVT+K+ KN Sbjct: 516 EVKTVTIKLGDKN 528 >1O9J-A nrPDB Length = 501 Score = 703 bits (1815), Expect = 0.0, Method: Composition-based stats. Identities = 348/493 (70%), Positives = 426/493 (86%) Query: 26 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 LP+P N++I++TK+FINNEW S SG+ FPV+NPAT E++CEV+EADK D+DKAV+AAR Sbjct: 9 LPAPLTNIKIQHTKLFINNEWHESVSGKTFPVFNPATEEKICEVEEADKEDVDKAVKAAR 68 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 AF +GS WR MDASERG+L+ KLADL+ERDR +LAT+ES+N GK F A+ +DL IK Sbjct: 69 EAFQMGSPWRTMDASERGQLIYKLADLIERDRLLLATLESINAGKVFASAYLMDLDYCIK 128 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 RY AGWADKI G TIPVDG++F++TRHEPIGVCG I PWN P+++ A KI PALCCGN Sbjct: 129 ALRYCAGWADKIQGRTIPVDGEFFSYTRHEPIGVCGLIFPWNAPMILLACKIGPALCCGN 188 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 TV++KPAEQTPL+AL++ +LIKEAGFPPGV+NI+PGYGPTAGAAI+SH+ +DK+AFTGST Sbjct: 189 TVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGST 248 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 EVGK+IQEAA +SNLKRVTLELG K+P I+FADADLD AVE AHQGVF NQGQ C A S+ Sbjct: 249 EVGKMIQEAAAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAASK 308 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 +FVEE+IY+EFV+RSVERAK+ V G+P P GPQI+K Q+NKI+ELI+SG EGAKL Sbjct: 309 LFVEEAIYDEFVQRSVERAKKYVFGNPLTPGVNHGPQINKAQHNKIMELIESGKKEGAKL 368 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 ECGG G KG+FI+PTVFSNVTDDMRIAKEEIFGPVQ+I++FK++DEVI+RANN+ +GL Sbjct: 369 ECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTYYGL 428 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 VA VFT D++KA+TVSSA+QAGTVW+NCY A +AQSP GGFKMSG+GREMGE+G+ EY+E Sbjct: 429 VAGVFTKDLDKAVTVSSALQAGTVWVNCYLAASAQSPAGGFKMSGHGREMGEYGIHEYTE 488 Query: 506 VKTVTVKIPQKNS 518 VKTVT+KI +KNS Sbjct: 489 VKTVTMKISEKNS 501 >5L13-A nrPDB Length = 517 Score = 703 bits (1814), Expect = 0.0, Method: Composition-based stats. Identities = 335/498 (67%), Positives = 410/498 (82%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 A+ +P+P E+ +IFINNEW ++ S + FP NP+TGE +C+V E DK D+DKA Sbjct: 20 AATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKA 79 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V+AAR AF LGS WRRMDAS RGRLL++LADL+ERDR LA +E+L+ GKP++ ++ VDL Sbjct: 80 VKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDL 139 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 V+K RYYAGWADK HG TIP+DGD+F++TRHEP+GVCGQIIPWNFPLLM AWK+ PA Sbjct: 140 DMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPA 199 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 L GN VV+K AEQTPL+ALY+ LIKEAGFPPGV+NI+PG+GPTAGAAIASH +DK+A Sbjct: 200 LATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVA 259 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTE+G++IQ AAG SNLKRVTLELGGKSPNII +DAD+D+AVEQAH +FFNQGQCC Sbjct: 260 FTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCC 319 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 AGSR FV+E IY+EFV RSV RAK RVVG+PFD TEQGPQ+D+ Q+ KIL I +G Sbjct: 320 CAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQ 379 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EGAKL CGG +G+FI+PTVF +V D M IAKEEIFGPV +IL+FKT++EV+ RANN Sbjct: 380 EGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANN 439 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 S +GL AAVFT D++KA +S A+QAGTVW+NCY+ AQSPFGG+KMSG+GRE+GE+GL Sbjct: 440 STYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGL 499 Query: 501 REYSEVKTVTVKIPQKNS 518 + Y+EVKTVTVK+PQKNS Sbjct: 500 QAYTEVKTVTVKVPQKNS 517 >1AG8-A nrPDB Length = 499 Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats. Identities = 333/498 (66%), Positives = 411/498 (82%) Query: 21 ASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKA 80 A+ +P+P E+ Y +IFINNEW ++ S + FP NP+TG+ +C V E DKAD+D+A Sbjct: 2 AATQAVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTVNPSTGDVICHVAEGDKADVDRA 61 Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V+AAR AF LGS WRRMDASERGRLL++LADL+ERDR LA +E+L+ GKP++ ++ VDL Sbjct: 62 VKAARAAFQLGSPWRRMDASERGRLLNRLADLIERDRTYLAALETLDNGKPYIISYLVDL 121 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPA 200 V+K RYYAGWADK HG TIP+DGDYF++TRHEP+GVCGQIIPWNFPLLM AWK+ PA Sbjct: 122 DMVLKCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPA 181 Query: 201 LCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 L GN VV+K AEQTPL+ALY+ LIKEAGFPPGV+N++PG+GPTAGAAIASH +DK+A Sbjct: 182 LATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIASHEDVDKVA 241 Query: 261 FTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCC 320 FTGSTEVG LIQ AAG+SNLKRVTLE+GGKSPNII +DAD+D+AVEQAH +FFNQGQCC Sbjct: 242 FTGSTEVGHLIQVAAGKSNLKRVTLEIGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCC 301 Query: 321 TAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA 380 AGSR FV+E IY EFV RSV RAK RVVG+PFD TEQGPQ+D+ Q+ K+L I+SG Sbjct: 302 CAGSRTFVQEDIYAEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKVLGYIKSGKE 361 Query: 381 EGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 EG KL CGG +G+FI+PTVF ++ D M IAKEEIFGPV +IL+FK+M+EV+ RANN Sbjct: 362 EGLKLLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSMEEVVGRANN 421 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 S +GL AAVFT D++KA +S A+QAGTVW+NCY+ AQSPFGG+K+SG+GRE+GE+GL Sbjct: 422 SKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGSGRELGEYGL 481 Query: 501 REYSEVKTVTVKIPQKNS 518 + Y+EVKTVTV++PQKNS Sbjct: 482 QAYTEVKTVTVRVPQKNS 499 >5GT6-A nrPDB Length = 508 Score = 636 bits (1640), Expect = 0.0, Method: Composition-based stats. Identities = 252/495 (50%), Positives = 328/495 (66%), Gaps = 2/495 (0%) Query: 19 LMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADID 78 ++ + L + K+FIN E+ ++ G+ F YNPAT + + V EA + DID Sbjct: 15 MLKTNIELKPKVEAFLNEEIKMFINGEFVSAIGGKTFETYNPATEDVLAVVCEAQEEDID 74 Query: 79 KAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYV 138 AV+AAR AF G W M +ER L+ KLADL+E R LA +E+L+ GKP+ A Sbjct: 75 AAVKAARSAFESGP-WAEMTTAERAHLIYKLADLIEEHREELAQLEALDNGKPYQVALDD 133 Query: 139 DLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIA 198 D+ ++ +RYYAGW KI G TIP+ DY +TRHEP+GV GQIIPWNFPL+M +WK+ Sbjct: 134 DISATVENYRYYAGWTTKIIGQTIPISKDYLNYTRHEPVGVVGQIIPWNFPLVMSSWKMG 193 Query: 199 PALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDK 258 AL G T+V+KPAEQTPLS LY L KEAGFP GV+N +PG+GP AGAAI +H IDK Sbjct: 194 AALATGCTIVLKPAEQTPLSLLYAAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDK 253 Query: 259 IAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQ 318 +AFTGST GK I + +K VTLELGGKSPNII DADL+ A+ A QG+ +N GQ Sbjct: 254 VAFTGSTVTGKYIMRQSAEM-IKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQ 312 Query: 319 CCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSG 378 C+AGSR+FV YE V V+ A +G+ + TE GP + KKQ ++L I+ G Sbjct: 313 NCSAGSRVFVHRKHYETVVDALVKMANNVKLGAGMEKETEMGPLVSKKQQERVLNYIEQG 372 Query: 379 VAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERA 438 EGA + GG+ KG+F++PTVF++VTDDM I KEEIFGPV +L F + +EVIERA Sbjct: 373 KKEGATVAAGGERALEKGYFVKPTVFTDVTDDMTIVKEEIFGPVVVVLPFDSTEEVIERA 432 Query: 439 NNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEF 498 NNS +GL A V+T +I V++ ++AGTVWIN YN NA +PFGG+K SG GRE+G + Sbjct: 433 NNSSYGLAAGVWTQNIKTGHQVANKLKAGTVWINDYNLENAAAPFGGYKQSGIGRELGSY 492 Query: 499 GLREYSEVKTVTVKI 513 L Y+EVK+V V I Sbjct: 493 ALDNYTEVKSVWVNI 507 >4PXL-B nrPDB Length = 517 Score = 627 bits (1617), Expect = e-180, Method: Composition-based stats. Identities = 244/484 (50%), Positives = 343/484 (70%), Gaps = 1/484 (0%) Query: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89 P +E+++TK+FI+ ++ ++ SG+ F +P TGE + + E DKAD+D AV+AAR AF Sbjct: 29 VPKVEVRFTKLFIDGKFVDAVSGKTFETRDPRTGEVIASIAEGDKADVDLAVKAAREAFD 88 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 G W RM ERGR+L + ADL++ LA +++++ GK F D+ G RY Sbjct: 89 NGP-WPRMTGYERGRILHRFADLIDEHVEELAALDTVDAGKLFAVGKARDIPGAAHLLRY 147 Query: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 YAG ADK+HG T+ + +T EP+GV G I+PWN+P MF +K+ PAL G VV+ Sbjct: 148 YAGAADKVHGATLKMAQRMHGYTLKEPVGVVGHIVPWNYPTTMFFFKVGPALAAGCAVVV 207 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPAEQTPLSAL+ L +EAG P GV+N++PG+GPTAGAA+A+H+ +DK++FTGSTEVG+ Sbjct: 208 KPAEQTPLSALFYAHLAREAGVPAGVLNVVPGFGPTAGAAVAAHMDVDKVSFTGSTEVGR 267 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 L+ AA SNLK V+LELGGKSP I+F DADLD AV + + N+G+ C AG+RI+V+ Sbjct: 268 LVMRAAAESNLKPVSLELGGKSPVIVFDDADLDMAVNLVNFATYTNKGEICVAGTRIYVQ 327 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 E IY+EFV+++ E A + VVG PF+P+ QGPQ+DK QY K+L I G EGA L GG Sbjct: 328 EGIYDEFVKKAAELASKSVVGDPFNPSVSQGPQVDKDQYEKVLRYIDIGKREGATLVTGG 387 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 K G KG++IEPT+F++V DDM IA++EIFGPV +++FKT++EVI++ANN+ +GL A + Sbjct: 388 KPCGDKGYYIEPTIFTDVKDDMTIAQDEIFGPVMALMKFKTVEEVIQKANNTRYGLAAGI 447 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 T +I+ A TVS +++AG +WINCY A + +PFGG+KMSG G++MG L +Y + KTV Sbjct: 448 VTKNIDVANTVSRSIRAGAIWINCYFAFDPDAPFGGYKMSGFGKDMGMDALDKYLQTKTV 507 Query: 510 TVKI 513 + Sbjct: 508 VTPL 511 >4PZ2-A nrPDB Length = 534 Score = 620 bits (1599), Expect = e-178, Method: Composition-based stats. Identities = 261/507 (51%), Positives = 341/507 (67%), Gaps = 13/507 (2%) Query: 10 GEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEV 69 GE K + L+ +P EI++TK+FIN + ++ SGR F +P TG + V Sbjct: 32 GEEKEERGQLL---FDVP------EIRFTKLFINGSFVDAVSGRTFDTRDPRTGGVIASV 82 Query: 70 QEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGG 129 EADK D+D AV+AAR AF G W RM SERGR++ +LADLVE LA +ESL+ G Sbjct: 83 AEADKEDVDLAVRAARAAFDHG-EWPRMSGSERGRIMARLADLVEEHAGELAALESLDAG 141 Query: 130 KPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFP 189 K VD+ + RY+AG ADKIHG T+ + G + T EP+GV G IIPWNFP Sbjct: 142 KHPAVTRAVDVGNAAGSLRYFAGAADKIHGETLKMPGQFQGHTLREPLGVAGVIIPWNFP 201 Query: 190 LLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAA 249 MFA K+APAL G +V+KPAEQTPLSALY+ L K+AG P GVIN++PG+GPTAGAA Sbjct: 202 STMFAVKVAPALAAGCALVVKPAEQTPLSALYLAQLAKQAGVPDGVINVVPGFGPTAGAA 261 Query: 250 IASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAH 309 +ASH+ +D ++FTGSTEVG+LI +A+ SNLK V LELGGKSP I+F DADLD AVE A Sbjct: 262 LASHMDVDMVSFTGSTEVGRLIMKASAESNLKPVYLELGGKSPLIVFDDADLDMAVELAV 321 Query: 310 QGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPF-DPTTEQGPQIDKKQY 368 FFN+G+ C A SR++V+E +Y+ F R ER + VVG PF DP +QGPQ+DK QY Sbjct: 322 GASFFNKGEACVAASRVYVQERVYDRFEERLAERMRSWVVGDPFSDPRADQGPQVDKAQY 381 Query: 369 NKILELIQSGVAEGAKLECGGKG--LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEIL 426 ++L I G EGA L GG+ KG++IEPTVF+NV +DM IAKEEIFGPV ++ Sbjct: 382 ERVLSYIDHGKREGATLLTGGRPCAPEGKGYYIEPTVFTNVKEDMIIAKEEIFGPVMCLM 441 Query: 427 RFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGF 486 +FKT++E I RAN++ +GL A V T D++ A V +++AG VW+NCY A+ + PFGG Sbjct: 442 KFKTVEEAIARANDTRYGLGAGVVTRDLDVANRVVRSVRAGVVWVNCYFAMGSDCPFGGR 501 Query: 487 KMSGNGREMGEFGLREYSEVKTVTVKI 513 KMSG G++ G L +Y VK+V + Sbjct: 502 KMSGFGKDEGMHALDKYLAVKSVVTPL 528 >4V3F-A nrPDB Length = 497 Score = 616 bits (1589), Expect = e-177, Method: Composition-based stats. Identities = 197/490 (40%), Positives = 290/490 (59%), Gaps = 11/490 (2%) Query: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93 I ++FI+ EW+ PV NP+T E + ++ A D++ AV AAR AF + Sbjct: 4 PIPARQLFIDGEWREPIKKNRIPVINPSTEEIIGDIPAATAEDVEVAVVAARRAF-RRNN 62 Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153 W + R L +A + + +E+++ GKPF +A +D+ V F Y+AG Sbjct: 63 WSATSGAHRATYLRAIAAKITEKKDHFVKLETIDSGKPFDEAV-LDIDDVASCFEYFAGQ 121 Query: 154 ADKIHGM-----TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 A+ + G T+P++ + + +P+GV G I PWN+PLLM WKIAPAL G T V Sbjct: 122 AEALDGKQKAPVTLPMER-FKSHVLRQPLGVVGLISPWNYPLLMATWKIAPALAAGCTAV 180 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 +KP+E ++ L G + E G PPGV+NIL G GP AGA + SH +DKIAFTGS+ G Sbjct: 181 LKPSELASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDVDKIAFTGSSATG 240 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 + +A + +K VTLELGGKSP ++F D D+D VE G F+ GQ C+A SR+ V Sbjct: 241 SKVMASAAQL-VKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTNGQICSATSRLLV 299 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 ESI EFV + V+ K + PF+ GP I K QY+KI++ I + +EGA + G Sbjct: 300 HESIAAEFVDKLVKWTKNIKISDPFEEGCRLGPVISKGQYDKIMKFISTAKSEGATILYG 359 Query: 389 GKGLGR--KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLV 446 G KG++IEPT+ ++++ M+I KEE+FGPV + F + DE I AN++++GL Sbjct: 360 GSRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTFSSEDEAIALANDTEYGLA 419 Query: 447 AAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEV 506 AAVF+ND+ + ++ A++ G VW+NC Q+P+GG K SG GRE+GE+G++ Y + Sbjct: 420 AAVFSNDLERCERITKALEVGAVWVNCSQPCFVQAPWGGIKRSGFGRELGEWGIQNYLNI 479 Query: 507 KTVTVKIPQK 516 K VT I + Sbjct: 480 KQVTQDISDE 489 >4O6R-A nrPDB Length = 496 Score = 607 bits (1566), Expect = e-174, Method: Composition-based stats. Identities = 208/484 (42%), Positives = 294/484 (60%), Gaps = 8/484 (1%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 T++FI+ + ++ V NP G + ++ A AD+D AV AA AF W Sbjct: 9 MQTQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAF---PAWS 65 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 M A+ERGRLL +LAD +E + LA +ESL+ G P + +D+ FRY+ G AD Sbjct: 66 AMPAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMAD 125 Query: 156 KIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 K+ G IPVD + + + PIGV GQI+PWNFPL+ +WK+ PAL GNTVV+KP+E T Sbjct: 126 KLQGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEIT 185 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 PLS L + L+ E GFP GV+NI+PGYG TAG +A H G+ KIAFTGST G+ I E A Sbjct: 186 PLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVE-A 244 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEE 335 + NLKRV LELGGK NI+F DA+LD A+ A +F NQGQ C AGSR+ + E I + Sbjct: 245 SQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADA 304 Query: 336 FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGR- 394 F+ R V A +G+P DP TE GP K+ +++L + +G ++ GG Sbjct: 305 FLERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDP 364 Query: 395 ---KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 G+++ PT+ R+A+EE+FGP +LRF + DE + AN +++GL + ++T Sbjct: 365 ALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWT 424 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 ND+++A +++ + AG WINCY +N SPFGG SG GREMG + +Y+E ++V V Sbjct: 425 NDLSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWV 484 Query: 512 KIPQ 515 + Sbjct: 485 NVDG 488 >4CAZ-A nrPDB Length = 490 Score = 605 bits (1561), Expect = e-173, Method: Composition-based stats. Identities = 198/489 (40%), Positives = 278/489 (56%), Gaps = 7/489 (1%) Query: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93 + K++I + + SG F NPA GE + +VQ A + D+++AVQ+A V Sbjct: 3 RFEEQKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVE---GQKV 59 Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153 W M A +R R+L + D++ LA +E+L+ GKP + VD+ YYAG Sbjct: 60 WAAMTAMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGL 119 Query: 154 ADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 I G IP+ F +TR EP+GV I WN+P+ + WK APAL GN ++ KP+E Sbjct: 120 VPAIEGEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSE 179 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 TPL+AL + + EAG P GV N+L G G G + H I+KI+FTG T GK + Sbjct: 180 VTPLTALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMA 239 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 +A S+LK VT+ELGGKSP IIF DADLD A + A FF+ GQ CT G+R+F+ S Sbjct: 240 SASSSSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQ 299 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 F + +ER +R +G P D T GP + +L I+SG A+ A+L CGG+ + Sbjct: 300 ARFEAKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVT 359 Query: 394 R----KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 KG ++ PTVF++ DDM I +EEIFGPV IL + DE I RAN++++GL A V Sbjct: 360 DGAFGKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGV 419 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 T D+ +A ++AG WIN + A+ P GG+K SG GRE G L Y+ +K+V Sbjct: 420 VTQDLARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSV 479 Query: 510 TVKIPQKNS 518 V++ S Sbjct: 480 QVELGDYAS 488 >3RHO-A nrPDB Length = 517 Score = 595 bits (1535), Expect = e-170, Method: Composition-based stats. Identities = 238/487 (48%), Positives = 326/487 (66%), Gaps = 8/487 (1%) Query: 33 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGS 92 L++ Y ++FI E+ ++E + + NP G +C+V A +D+DKAV AA+ AF G Sbjct: 33 LQMPY-QLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENG- 90 Query: 93 VWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAG 152 +W +++A +RGRLL +LAD++E+ + LAT+E+L+ G + A + I+TFRY+AG Sbjct: 91 LWGKINARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAG 150 Query: 153 WADKIHGMTIPVDGDY----FTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 W DKI G TIP++ T T+ EP+GVCG +IPWN+PL+M +WK A L GNTVV Sbjct: 151 WCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVV 210 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 IKPA+ TPL+AL L +AG P GV+NILPG G G ++ H + KI FTGSTEVG Sbjct: 211 IKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVG 270 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 K I ++ SN+K+V+L+LGGKSP IIFAD DL+ AV+ VFFN+G+ C A R+FV Sbjct: 271 KHIMKSCALSNVKKVSLQLGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFV 330 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 EESI+ +FV++ VE ++ +G+P + T GPQ + K++E Q GV EGA L CG Sbjct: 331 EESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCG 390 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRF--KTMDEVIERANNSDFGLV 446 G + R GFF +PTVF++V D M IAKEE FGP+ I RF +D V+ RAN ++FGL Sbjct: 391 GNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLA 450 Query: 447 AAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEV 506 + VFT DINKAL VS +QAGTV+IN YN + +PFGGFK SG G+++GE L EY + Sbjct: 451 SGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRI 510 Query: 507 KTVTVKI 513 KTVT + Sbjct: 511 KTVTFEY 517 >3IWK-A nrPDB Length = 503 Score = 586 bits (1510), Expect = e-167, Method: Composition-based stats. Identities = 198/493 (40%), Positives = 286/493 (58%), Gaps = 12/493 (2%) Query: 33 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAF--SL 90 + + ++FI+ EW+ + P NP+T + ++ A K D+D AV AA+ A Sbjct: 3 ITVSSRQLFIDGEWRVPILNKRIPNINPSTENIIGDIPAATKEDVDLAVDAAKRAISRKN 62 Query: 91 GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYY 150 G W S R R L +A ++ + L +ES++ GKP +A DL V+ F YY Sbjct: 63 GRDWSAASGSLRARYLRAIAAKIKEKKDELGKLESIDCGKPLEEAL-ADLDDVVACFEYY 121 Query: 151 AGWADKIHGM-----TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 AG A+++ ++P+D + ++ EPIGV I PWN+P LM WKIAPAL G Sbjct: 122 AGLAEELDSKQKAPISLPMDT-FKSYILKEPIGVVALITPWNYPFLMATWKIAPALAAGC 180 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 ++KP+E ++ L +G + KE G P GV+NI+ G G AGA++ASH +DKI+FTGS+ Sbjct: 181 AAILKPSELASVTCLELGEICKEVGLPRGVLNIVTGLGHEAGASLASHPDVDKISFTGSS 240 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 G I A + +K V+LELGGKSP ++F D DLD E G FF GQ C+A SR Sbjct: 241 ATGSKIMTTAAQL-VKPVSLELGGKSPIVVFEDVDLDKVAEWTVFGCFFTNGQICSATSR 299 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 + V ESI EFV + V+ A+ + P + GP + + QY K+L I S +EGA + Sbjct: 300 LIVHESIAVEFVDKLVKWAENIKISDPLEEGCRLGPIVSEAQYKKVLNCISSAKSEGATI 359 Query: 386 ECGGKGLGR--KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDF 443 GG+ KG+F+EPT+ ++VT M+I +EE+FGPV + F T +E I AN++ + Sbjct: 360 LTGGRRPEHLKKGYFVEPTIITDVTTSMQIWREEVFGPVLAVKTFSTEEEAINLANDTHY 419 Query: 444 GLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREY 503 GL +AV +ND+ + +S A+QAG VWINC Q+P+GG K SG GRE+GE+GL Y Sbjct: 420 GLGSAVMSNDLERCERLSKALQAGIVWINCAQPSFIQAPWGGIKRSGFGRELGEWGLENY 479 Query: 504 SEVKTVTVKIPQK 516 VK VT + Sbjct: 480 LSVKQVTRYTSDE 492 >3IWJ-A nrPDB Length = 503 Score = 584 bits (1506), Expect = e-167, Method: Composition-based stats. Identities = 206/494 (41%), Positives = 296/494 (59%), Gaps = 12/494 (2%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL- 90 ++ I ++FIN +W+ + PV NPAT + ++ A K D+D AV AA+ A + Sbjct: 2 DIPIPTRQLFINGDWKAPVLNKRIPVINPATQNIIGDIPAATKEDVDVAVAAAKTALTRN 61 Query: 91 -GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 G+ W + R R L +A V + LA +ES++ GKP +A + D+ V F Y Sbjct: 62 KGADWATASGAVRARYLRAIAAKVTEKKPELAKLESIDCGKPLDEAAW-DIDDVAGCFEY 120 Query: 150 YAGWADKIHGM-----TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCG 204 YA A+K+ ++P+D + + EPIGV G I PWN+P+LM WK+APAL G Sbjct: 121 YADLAEKLDARQKAPVSLPMDT-FKSHVLREPIGVVGLITPWNYPMLMATWKVAPALAAG 179 Query: 205 NTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGS 264 ++KP+E L+ L +G + KE G PPGV+NIL G GP AGA +A+H +DK+AFTGS Sbjct: 180 CAAILKPSELASLTCLELGEICKEVGLPPGVLNILTGLGPEAGAPLATHPDVDKVAFTGS 239 Query: 265 TEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS 324 + G I AA + +K V+LELGGKSP ++F D DLD A E A G F+ GQ C+A S Sbjct: 240 SATGSKIMTAAAQL-VKPVSLELGGKSPLVVFEDVDLDKAAEWAIFGCFWTNGQICSATS 298 Query: 325 RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 R+ + ESI EF+ R V+ K + P + GP + + QY KIL+ + + +EGA Sbjct: 299 RLILHESIATEFLNRIVKWIKNIKISDPLEEGCRLGPVVSEGQYEKILKFVSNAKSEGAT 358 Query: 385 LECGGKGLGR--KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSD 442 + GG KGFFIEPT+ ++VT +M+I +EE+FGPV + F T +E I+ AN++ Sbjct: 359 ILTGGSRPEHLKKGFFIEPTIITDVTTNMQIWREEVFGPVLCVKTFSTEEEAIDLANDTV 418 Query: 443 FGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLRE 502 +GL AAV +ND+ + V+ A +AG VW+NC Q+P+GG K SG GRE+GE+GL Sbjct: 419 YGLGAAVISNDLERCERVTKAFKAGIVWVNCSQPCFTQAPWGGVKRSGFGRELGEWGLDN 478 Query: 503 YSEVKTVTVKIPQK 516 Y VK VT I ++ Sbjct: 479 YLSVKQVTQYISEE 492 >4GO4-A nrPDB Length = 495 Score = 584 bits (1505), Expect = e-167, Method: Composition-based stats. Identities = 208/485 (42%), Positives = 301/485 (62%), Gaps = 9/485 (1%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 +++I+ + ++ +G V +P G + + A+ AD+D AV AA+ AF W Sbjct: 1 MQNQLYIDGRFVDAVAGGTIDVVSPHDGSLITRIAAAEAADVDLAVAAAKRAF---PAWS 57 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 + A+ERGRLL KLAD +E LA +ESLN G P + +D+ FRY+ G AD Sbjct: 58 ALGAAERGRLLLKLADRIEECSEELAQLESLNTGHPIRDSRGLDVPRTAACFRYFGGMAD 117 Query: 156 KIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 KI G IPVD + + + +PIGV QI+PWNFPL+ +WK+ PAL GNT+VIKP+E T Sbjct: 118 KIEGSVIPVDAGFLNYVQRKPIGVVAQIVPWNFPLMFTSWKMGPALAAGNTIVIKPSEIT 177 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 PLS L + L+ E GFP GV+N++PGYG TAG A+A H+ + KIAFTGST G+ I E A Sbjct: 178 PLSTLRIVELMTEVGFPKGVVNVVPGYGHTAGQALAEHLDVGKIAFTGSTATGRRIVE-A 236 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEE 335 +SNLKR+ LELGGK NI+F DA+++ AV A +F NQGQ C AGSR+ + + I ++ Sbjct: 237 SKSNLKRIQLELGGKGANIVFEDANIEAAVNGAAWAIFHNQGQACIAGSRLILHKDIADQ 296 Query: 336 FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 F+ R + AK +G P DP TE GP + +++L I + +G K+ GGK K Sbjct: 297 FLERFIALAKSIRLGDPMDPETEMGPLTSALRRDRVLSYIDIAIEQGGKVLAGGKAPDDK 356 Query: 396 ----GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 GF++EPTV D R+ +EE+FGP ++RF + +E + ANN+++GL + ++T Sbjct: 357 ALANGFYVEPTVVEAKPQD-RVCQEEVFGPFVTVVRFSSDEEALAIANNTEYGLGSGLWT 415 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 ++ +A ++ A+ AG WINCY ++ SPFGG SG GREMG + +Y+E ++V V Sbjct: 416 QNLARAHKMAHAIHAGMCWINCYKRVSPGSPFGGVGQSGYGREMGFEAIHDYTEARSVWV 475 Query: 512 KIPQK 516 + K Sbjct: 476 NVDAK 480 >4MPY-A nrPDB Length = 520 Score = 579 bits (1492), Expect = e-165, Method: Composition-based stats. Identities = 200/479 (41%), Positives = 287/479 (59%), Gaps = 8/479 (1%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + +I+ EW S + + NP E + V E K D ++A+ AAR AF G W + Sbjct: 34 RQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESG-EWSQET 92 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 A RG+ + +AD ++ R LA +E+L+ GK +++ D+ + F Y+AG ADK Sbjct: 93 AETRGKKVRAIADKIKEHREALARLETLDTGKTLEESY-ADMDDIHNVFMYFAGLADKDG 151 Query: 159 GMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G I D + EP+GV QI PWN+PLL +WKIAPAL G ++V+KP+E TPL Sbjct: 152 GEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPL 211 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 + + + L++E GFP G IN++ G G G ++ H +D ++FTG E GK I + A Sbjct: 212 TTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAA- 270 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 +N+ + LELGGK+PNIIF DAD + AV+QA G +F+ GQ C+AGSRI V+ SI ++F Sbjct: 271 NNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFE 330 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK-- 395 + ++R K+ +G+ FD TE GP I + NKI + AEGA + GGK R Sbjct: 331 QALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDL 390 Query: 396 --GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 G F EPTV +N MRI +EE+FGPV + F+T E I+ AN+S +GL AVF+ D Sbjct: 391 KDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKD 450 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 I KA V++ ++ GTVWIN ++ AQ+P+GG+K SG GRE+G+ GL EY K + Sbjct: 451 IGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTN 509 >3JZ4-A nrPDB Length = 481 Score = 576 bits (1484), Expect = e-164, Method: Composition-based stats. Identities = 171/485 (35%), Positives = 264/485 (54%), Gaps = 6/485 (1%) Query: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89 + + + IN EW ++ +G V NPA G+++ V + + A+ AA A Sbjct: 2 LNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRAL- 60 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 WR + A ER +L +L+ + LA + +L GKP +A ++ + Sbjct: 61 --PAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEA-KGEISYAASFIEW 117 Query: 150 YAGWADKIHGMTIPV-DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 +A +I+G TIP D +PIGV I PWNFP M K PAL G T+V Sbjct: 118 FAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMV 177 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 +KPA QTP SAL + L AG P GV N++ G G + S+ + K++FTGSTE+G Sbjct: 178 LKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIG 237 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 + + E + ++K+V+LELGG +P I+F DADLD AVE A F N GQ C +R++V Sbjct: 238 RQLMEQCAK-DIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYV 296 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 ++ +Y+ F + + + +G D GP ID+K K+ E I + +GA++ CG Sbjct: 297 QDGVYDRFAEKLQQAMSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCG 356 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 GK R G F +PT+ +V + +++KEE FGP+ + RFK +VI +AN+++FGL A Sbjct: 357 GKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAY 416 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 + D+++ V A++ G V IN N +PFGG K SG GRE ++G+ +Y E+K Sbjct: 417 FYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKY 476 Query: 509 VTVKI 513 + + + Sbjct: 477 MCIGL 481 >1BPW-A nrPDB Length = 503 Score = 574 bits (1480), Expect = e-164, Method: Composition-based stats. Identities = 196/498 (39%), Positives = 292/498 (58%), Gaps = 13/498 (2%) Query: 28 SPTPNLEIKYTKIFINNEWQNSESGRV-FPVYNPATGEQVCEVQEADKADIDKAVQAARL 86 + T ++ + + S+ G PV+ PATG +C++ ++D+AVQ+A+ Sbjct: 10 ASTGSVVVTDDLNYWGGRRIKSKDGATTEPVFEPATGRVLCQMVPCGAEEVDQAVQSAQA 69 Query: 87 AFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT 146 A+ W +M ER R++ + A ++ R +A +E +N GK +A Y D+ + Sbjct: 70 AYL---KWSKMAGIERSRVMLEAARIIRERRDNIAKLEVINNGKTITEAEY-DIDAAWQC 125 Query: 147 FRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNT 206 YYAG A + G I + G F +TR EP+GVC I+ WN+P ++ AWK APAL CGN Sbjct: 126 IEYYAGLAPTLSGQHIQLPGGAFAYTRREPLGVCAGILAWNYPFMIAAWKCAPALACGNA 185 Query: 207 VVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTE 266 VV KP+ TP++ + + + EAG P G++N++ G G G+ + H + K++FTGS Sbjct: 186 VVFKPSPMTPVTGVILAEIFHEAGVPVGLVNVVQG-GAETGSLLCHHPNVAKVSFTGSVP 244 Query: 267 VGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRI 326 GK + E + ++ +K VTLELGGKSP +IF D +L+ AV A F QGQ CT G+R+ Sbjct: 245 TGKKVMEMSAKT-VKHVTLELGGKSPLLIFKDCELENAVRGALMANFLTQGQVCTNGTRV 303 Query: 327 FVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLE 386 FV+ I +F+ V+R K VVG P T G I K Q +K+L + EGA++ Sbjct: 304 FVQREIMPQFLEEVVKRTKAIVVGDPLLTETRMGGLISKPQLDKVLGFVAQAKKEGARVL 363 Query: 387 CGGKGLGR------KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 CGG+ L G+F+ P V N DDM KEEIFGPV +L F T +EV++RANN Sbjct: 364 CGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANN 423 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 500 + FGL + VFT DI++A V++ ++AGT +IN Y+ + PFGG+KMSG GRE G+ + Sbjct: 424 TTFGLASGVFTRDISRAHRVAANLEAGTCYINTYSISPVEVPFGGYKMSGFGRENGQATV 483 Query: 501 REYSEVKTVTVKIPQKNS 518 YS++KTV V++ +S Sbjct: 484 DYYSQLKTVIVEMGDVDS 501 >6QAO-A nrPDB Length = 508 Score = 571 bits (1471), Expect = e-163, Method: Composition-based stats. Identities = 190/499 (38%), Positives = 275/499 (55%), Gaps = 13/499 (2%) Query: 27 PSPTPNLEIKYTKIFINNEWQNSESGR-VFPVYNPATGEQVCEVQEADKADIDKAVQAAR 85 P T + + + PATG + + + +++ AVQ A+ Sbjct: 14 PMSTGTFVVSQPLNYRGGARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAK 73 Query: 86 LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 AF +W + ER R+L + A ++ +ATME +N GK +A +D+ + Sbjct: 74 AAF---KIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEA-RLDIDISWQ 129 Query: 146 TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 YYAG A + G I + G F +TR EP+GVC I WN+P + +WK APAL CGN Sbjct: 130 CLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGN 189 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 +V KP+ TP+SAL + + EAG PPG+ N++ G G G + H + K++FTGS Sbjct: 190 AMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSV 248 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 G I E + + +K VTLELGGKSP IIF+D D++ AV+ A F QGQ C G+R Sbjct: 249 PTGMKIMEMSAK-GIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTR 307 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 +FV++ I ++F V++ +R +G P T GP I++ ++L ++ +GAK+ Sbjct: 308 VFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKV 367 Query: 386 ECGGK------GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERAN 439 CGG + G+++ P V +N DDM KEEIFGPV IL F T EV+ERAN Sbjct: 368 LCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERAN 427 Query: 440 NSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFG 499 ++ FGL A VFT DI +A V + +QAGT +IN YN + PFGG+K SG GRE G Sbjct: 428 DTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVT 487 Query: 500 LREYSEVKTVTVKIPQKNS 518 + YS++KTV V++ S Sbjct: 488 IEYYSQLKTVCVEMGDVES 506 >6B4R-B nrPDB Length = 497 Score = 570 bits (1470), Expect = e-163, Method: Composition-based stats. Identities = 205/485 (42%), Positives = 306/485 (63%), Gaps = 5/485 (1%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 +L+I+ + F+N E+ N+ SG F +P G + +V D AD ++AV+ AR AF G Sbjct: 15 DLKIEG-RAFVNGEYSNAASGETFDCLSPVDGRFLAKVASCDLADAEQAVKVARNAFDSG 73 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 W R+ ++R + + + ADL+ + LA +E+L+ GKP + ++D+ + R+ A Sbjct: 74 -AWSRLAPAKRKQTMIRFADLLLENAEELALLETLDMGKPISDSLHIDVASAANSLRWSA 132 Query: 152 GWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 DKI+ EP+GV I+PWNFPLLM WK+ PAL GN+V++KP Sbjct: 133 EAIDKIYDEVAATPHAELGLVTREPVGVVAAIVPWNFPLLMSCWKLGPALATGNSVILKP 192 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 +E++PL+A+ + L EAG P GV N+LPGYG T G A+A H+ +D + FTGST++ K + Sbjct: 193 SEKSPLTAIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHMDVDTLVFTGSTKIAKQL 252 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 AG SN+KRV LE GGKSPNI+FADA DL A E A + FNQG+ CTAGSR+ VE Sbjct: 253 MVYAGESNMKRVWLEAGGKSPNIVFADAPDLKAAAEAAAGAIAFNQGEVCTAGSRLLVER 312 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 SI ++F+ +E K G+P DP T G +D +Q N +L I++G +GAKL GGK Sbjct: 313 SIKDKFLPLVIEALKGWKPGNPLDPETNVGALVDTQQMNTVLSYIEAGHNDGAKLVAGGK 372 Query: 391 GLGRK--GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 + G ++EPT+F VT+ M+IA+EEIFGPV ++ F+ +E + AN++ +GL AA Sbjct: 373 RTLEETGGTYVEPTIFDGVTNAMKIAREEIFGPVLSVIEFEDAEEAVRIANDTPYGLAAA 432 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 V+T++++KA + A++AG+VW+N Y+ + +PFGGFK SGNGR+ +Y+E+K Sbjct: 433 VWTSNLSKAHLTAKALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELKA 492 Query: 509 VTVKI 513 +K+ Sbjct: 493 TWIKL 497 >4QYJ-A nrPDB Length = 516 Score = 570 bits (1469), Expect = e-163, Method: Composition-based stats. Identities = 215/483 (44%), Positives = 306/483 (63%), Gaps = 10/483 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 ++ I +W +++SG+ VYNPATG+ + EV + D D++ AV++A A WRRM Sbjct: 36 QMLIGGQWVSAQSGKTLNVYNPATGDILTEVPDGDVEDVNAAVESA-AATLRSDTWRRMP 94 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 S R R+L +LADL+E LA +E+LN GK + + +++ + RY AGWA K+ Sbjct: 95 PSARERILLRLADLLEVHGDELARLETLNNGKLLIYSKLMEVGASAQWLRYMAGWATKLT 154 Query: 159 GMTI------PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPA 212 G T+ P + T+ P+GV IIPWNFPLLM WKIAPAL CGNTVV+KPA Sbjct: 155 GSTLDLSLPLPPEVRSRASTQRVPVGVVAAIIPWNFPLLMAVWKIAPALACGNTVVLKPA 214 Query: 213 EQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQ 272 E+TPL+AL + L EAG P G +N++ G G TAG A+ H + K+AFTGSTEVG++I Sbjct: 215 EETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDALVRHPKVAKVAFTGSTEVGRIIG 274 Query: 273 EAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESI 332 A GRS LK V+LELGGKSP I+ AD D A E A +FFN GQ CTAGSR++V ESI Sbjct: 275 SACGRS-LKAVSLELGGKSPVIVLADCDPQEAAEGAAAAIFFNHGQVCTAGSRLYVHESI 333 Query: 333 YEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG-KG 391 YE+ ++R + VVGS + GP + KK + +L I++G+ +GA L CGG + Sbjct: 334 YEDVIQRLAVIGESIVVGSGLEQGVHMGPMVSKKHHENVLRHIRNGIEDGADLICGGTEA 393 Query: 392 LGRKGFFIEPTVFSNV-TDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 +GFF++PT+F+N D+R+ +E+FGPV F + EV+ AN S +GL A+++ Sbjct: 394 PCAQGFFVKPTIFANREKKDIRLLSQEVFGPVLVATPFSDIAEVVNEANRSVYGLGASIW 453 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 TND++ AL ++ ++AGTVW+N +N ++ PFGGFK SG GRE G + Y+ +++ Sbjct: 454 TNDLSAALRINDELEAGTVWVNTHNMVDPNLPFGGFKDSGVGREHGAAAIEHYTTTRSLV 513 Query: 511 VKI 513 + Sbjct: 514 IAY 516 >4I8Q-A nrPDB Length = 514 Score = 567 bits (1462), Expect = e-162, Method: Composition-based stats. Identities = 187/494 (37%), Positives = 281/494 (56%), Gaps = 10/494 (2%) Query: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89 N+ I +++I EW+ P+ NPAT E + ++ A D+D AV+AAR A + Sbjct: 16 NRNVPIPRRQLYIGGEWREPVKKNRIPIINPATEEIIGDIPAATAEDVDIAVEAARKAIA 75 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 W ++R + L +A V ++VLAT+ESL+ GK ++ D+ V F Y Sbjct: 76 R-DDWGSTTGAQRAKYLRAIAAKVLEKKSVLATLESLDSGKTLYESA-ADMDDVAGCFEY 133 Query: 150 YAGWADKIHGMTIPV----DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 YAG A+ + + Y ++ EP+GV G I PWN+PLLM WK+APAL G Sbjct: 134 YAGLAEALDSRRMTPVNLNSDSYKSYVLREPLGVVGLITPWNYPLLMAIWKVAPALAAGC 193 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 ++KP+E ++ L +G + +E G P G +NIL G GP AG +ASH +DKI+FTGS Sbjct: 194 AAILKPSELASITCLELGEICREIGLPSGALNILTGLGPEAGGPLASHPHVDKISFTGSG 253 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD-LDYAVEQAHQGVFFNQGQCCTAGS 324 G I AA + +K V+L LGGKSP ++F D D LD A E G+F N GQ C+A S Sbjct: 254 PTGSKIMTAAAQL-VKPVSLALGGKSPIVVFDDIDNLDIAAEWTLFGIFANTGQVCSATS 312 Query: 325 RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 R+ V+E+I F+ R ++ K + P + + GP + QY K+L+ I + +EGA Sbjct: 313 RLIVQENIASAFMDRLLKWTKNIKISDPLEEDCKLGPVVSAGQYEKVLKFISNAKSEGAT 372 Query: 385 LECGGKGLGR--KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSD 442 + CGG+ KG++++PT+ ++V M I KEE+FGPV + FKT ++ IE AN++ Sbjct: 373 ILCGGERPQHLKKGYYVQPTIITDVNTSMEIWKEEVFGPVLCVKTFKTEEQAIELANDTK 432 Query: 443 FGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLRE 502 +GL AAV + D+ + + A Q G +WINC + P+GG K SG GR++G++GL Sbjct: 433 YGLGAAVMSKDVKRCERFTKAFQTGIIWINCSQPTFNELPWGGKKRSGFGRDLGKWGLEN 492 Query: 503 YSEVKTVTVKIPQK 516 + +K VT + Sbjct: 493 FLNIKQVTEYTSAE 506 >5IUV-A nrPDB Length = 497 Score = 567 bits (1462), Expect = e-162, Method: Composition-based stats. Identities = 205/486 (42%), Positives = 303/486 (62%), Gaps = 5/486 (1%) Query: 31 PNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL 90 NL+I+ + FI E+ + SG F +P G + +V D AD +AV++AR AF Sbjct: 14 QNLKIEG-RAFIQGEYTAAASGETFDCISPVDGRLLAKVASCDAADAQRAVESARSAFDS 72 Query: 91 GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYY 150 G W R+ ++R + + A L+E++ LA +E+L+ GKP + VD+ G + + Sbjct: 73 G-AWSRLAPAKRKATMIRFAGLLEQNAEELALLETLDMGKPISDSLGVDIPGGARALSWS 131 Query: 151 AGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 DK++ D EP+GV I+PWNFPL+M WK+ PAL GN+VV+K Sbjct: 132 GEAIDKLYDEVAATPHDQLGLVTREPVGVVAAIVPWNFPLMMACWKLGPALSTGNSVVLK 191 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 P+E++PL+A+ + L EAG P GV+N+LPGYG T G A+A H+ +D + FTGST++ K Sbjct: 192 PSEKSPLTAIRIAQLAIEAGIPAGVLNVLPGYGHTVGKALALHMDVDTVVFTGSTKIAKQ 251 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 + AG SN+KRV LE GGKSPNI+FADA DL A + A + FNQG+ CTAGSR+ VE Sbjct: 252 LMIYAGESNMKRVWLEAGGKSPNIVFADAPDLQAAADSAASAIAFNQGEVCTAGSRLLVE 311 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 SI + F+ +E G+P DP T G +D +Q N +L I +G +GA+L GG Sbjct: 312 RSIKDRFLPMVIEALGTWKPGNPLDPATNVGALVDTQQMNTVLSYIAAGHTDGARLVAGG 371 Query: 390 KGLGRK--GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVA 447 K + ++ G ++EPT+F V + MRIA+EEIFGPV +L F T +E I+ AN++ +GL A Sbjct: 372 KQILQETGGTYVEPTIFDGVNNAMRIAQEEIFGPVLSVLTFDTAEEAIQIANDTPYGLAA 431 Query: 448 AVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVK 507 AV+T +++KA + A++AG+VW+N Y+ + +PFGGFK SGNGR+ +Y+E+K Sbjct: 432 AVWTANLSKAHLTARALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELK 491 Query: 508 TVTVKI 513 + +K+ Sbjct: 492 STWIKL 497 >4I8P-A nrPDB Length = 520 Score = 566 bits (1460), Expect = e-162, Method: Composition-based stats. Identities = 198/499 (39%), Positives = 281/499 (56%), Gaps = 12/499 (2%) Query: 27 PSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARL 86 P+ + ++F++ EW+ GR PV NP T + E+ D+D AV AAR Sbjct: 14 PNSASPAMVPLRQLFVDGEWRPPAQGRRLPVVNPTTEAHIGEIPAGTAEDVDAAVAAARA 73 Query: 87 AFSL--GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVI 144 A G W R + R + L +A V + LA +E+L+ GKP+ +A + D+ V Sbjct: 74 ALKRNRGRDWARAPGAVRAKYLRAIAAKVIERKPELAKLEALDCGKPYDEAAW-DMDDVA 132 Query: 145 KTFRYYAGWADKIHGM-----TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAP 199 F Y+A A+ + ++P++ + R EPIGV G I PWN+PLLM WKIAP Sbjct: 133 GCFEYFADQAEALDKRQNSPVSLPMET-FKCHLRREPIGVVGLITPWNYPLLMATWKIAP 191 Query: 200 ALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKI 259 AL G T V+KP+E ++ L + + KE G P GV+NI+ G GP AGA +++H +DK+ Sbjct: 192 ALAAGCTAVLKPSELASVTCLELADICKEVGLPSGVLNIVTGLGPDAGAPLSAHPDVDKV 251 Query: 260 AFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQC 319 AFTGS E GK I +A +K VTLELGGKSP ++F D D+D AVE G F+ GQ Sbjct: 252 AFTGSFETGKKIMASAA-PMVKPVTLELGGKSPIVVFDDVDIDKAVEWTLFGCFWTNGQI 310 Query: 320 CTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGV 379 C+A SR+ + I ++F R V AK V P + GP + + QY KI + I + Sbjct: 311 CSATSRLLIHTKIAKKFNERMVAWAKNIKVSDPLEEGCRLGPVVSEGQYEKIKKFISNAK 370 Query: 380 AEGAKLECGGKGLG--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIER 437 ++GA + GG KGFFIEPT+ +++T M I +EE+FGPV + F T DE IE Sbjct: 371 SQGATILTGGVRPAHLEKGFFIEPTIITDITTSMEIWREEVFGPVLCVKEFSTEDEAIEL 430 Query: 438 ANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGE 497 AN++ +GL AV + D + +S + AG +W+NC Q+P+GG K SG GRE+GE Sbjct: 431 ANDTQYGLAGAVISGDRERCQRLSEEIDAGCIWVNCSQPCFCQAPWGGNKRSGFGRELGE 490 Query: 498 FGLREYSEVKTVTVKIPQK 516 G+ Y VK VT I + Sbjct: 491 GGIDNYLSVKQVTEYISDE 509 >4O5H-A nrPDB Length = 511 Score = 562 bits (1449), Expect = e-160, Method: Composition-based stats. Identities = 225/484 (46%), Positives = 305/484 (63%), Gaps = 8/484 (1%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 K ++ I EW ++ SGR V NPA G + V EAD+ D+ +AV AAR AF G WR Sbjct: 29 KPKQMLIGAEWSDAASGRQLDVVNPADGTVIARVPEADERDVQQAVAAARRAFDAGP-WR 87 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 ++R RL+ LADL+E + LA +ESL+ GKP + A +D+ + FRY AGWA Sbjct: 88 TAKTTDRERLMLVLADLIEANARELAEIESLDNGKPVMVAQGLDVAMAAQCFRYMAGWAT 147 Query: 156 KIHGMTI------PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 KI G I D + F +TR EP+GV G IIPWNFPLLM AWKIAPAL G TVV+ Sbjct: 148 KIEGSVIDAGMPYLPDSEIFAYTRKEPVGVVGAIIPWNFPLLMAAWKIAPALATGCTVVL 207 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPAE TPLSAL +G LI+ AGFP GV+NI+ GYG TAGAA++ IDKIAFTGST+ GK Sbjct: 208 KPAEDTPLSALRLGELIQAAGFPDGVVNIVTGYGHTAGAALSRDPRIDKIAFTGSTQTGK 267 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 I A N+ R++LELGGKSP I+ D DLD A + +FFNQGQ CTAGSR ++ Sbjct: 268 TIG-HAALDNMTRMSLELGGKSPVIVLPDVDLDKAAQGVANAIFFNQGQVCTAGSRAYIH 326 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 +++ + R + A +G DP T+ GP + KQ ++ I SG EGA+ GG Sbjct: 327 SKVFDGVIERVAKIAASLKIGPGMDPATQIGPLVSAKQRERVCGYIDSGFGEGARAAAGG 386 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 + + GFF+EPTV + T MR+ +EEIFGPV + F +D ++ AN++ +GL A++ Sbjct: 387 RAIDGPGFFVEPTVLVDTTQAMRVVREEIFGPVLVAMPFDDVDTAVQLANDTPYGLGASI 446 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 ++ND++ + + AGTVW+NC++ L+ PFGG K SG GRE+G + +Y+E K+V Sbjct: 447 WSNDLSAIHKLVPRIAAGTVWVNCHSLLDNALPFGGMKQSGFGRELGRAVIDQYTESKSV 506 Query: 510 TVKI 513 + Sbjct: 507 MMNY 510 >2D4E-A nrPDB Length = 515 Score = 561 bits (1445), Expect = e-160, Method: Composition-based stats. Identities = 194/492 (39%), Positives = 292/492 (59%), Gaps = 15/492 (3%) Query: 31 PNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSL 90 L+ + FI E+ SESG FP +PAT E + + ++D+A +AA AF Sbjct: 20 RRLKERPALHFIAGEFVPSESGETFPSLDPATNEVLGVAARGGEREVDRAAKAAHEAFQR 79 Query: 91 GSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYY 150 W R A ER R L ++A+L+E+ LA ME L+ G+ + + F +Y Sbjct: 80 ---WSRTKAKERKRYLLRIAELIEKHADELAVMECLDAGQVLRIV-RAQVARAAENFAFY 135 Query: 151 AGWAD-KIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 A +A+ + T PVD D+ +T P G G I PWN PL++ W+IAPAL GNTVV+ Sbjct: 136 AEYAEHAMEDRTFPVDRDWLYYTVRVPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVL 195 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPAE +P +A + ++KEA PPGV N++ G+G AGAA+ +H + + TG TE GK Sbjct: 196 KPAEWSPFTATKLAEILKEADLPPGVFNLVQGFGEEAGAALVAHPLVPLLTLTGETETGK 255 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 ++ A +LKR++ ELGGKSP ++FADADL+ A++ +F G+ CTA SR+ VE Sbjct: 256 IVMRNAA-DHLKRLSPELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVE 314 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 E I+E+FV + VERA+ VG P DP TE GP I + ++L +++G EGA+L GG Sbjct: 315 EKIFEDFVGKVVERARAIRVGHPLDPETEVGPLIHPEHLQRVLGYVEAGKREGARLLVGG 374 Query: 390 KGLG--------RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNS 441 + +G ++ PTVF + M+IA+EEIFGPV + FK +E + +AN++ Sbjct: 375 ERAKTSFRGEDLSRGNYLLPTVFVG-ENHMKIAQEEIFGPVLVAIPFKDEEEALRKANDT 433 Query: 442 DFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLR 501 +GL A VFT D+ +A ++ ++AG V++N +N + +PFGG K SG+ RE G + L Sbjct: 434 KYGLAAYVFTRDLERAHRLALELEAGMVYLNSHNVRHLPTPFGGVKGSGDRREGGTYALD 493 Query: 502 EYSEVKTVTVKI 513 Y+++KT+ + + Sbjct: 494 FYTDLKTIALPL 505 >3R31-A nrPDB Length = 517 Score = 557 bits (1435), Expect = e-159, Method: Composition-based stats. Identities = 192/480 (40%), Positives = 277/480 (57%), Gaps = 10/480 (2%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 FI+ ++ +G F PATGE + ++ A A +++A+ +A+ A W Sbjct: 13 PKASHFIDGDYVEDNTGTPFESIFPATGEMIAKLHAATPAIVERAIASAKRA---QKEWA 69 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 M RGR+L + AD++ L+T+E+L+ GKP + D F ++ G A Sbjct: 70 AMSPMARGRILKRAADIMRERNDALSTLETLDTGKPIQETIVADPTSGADAFEFFGGIAP 129 Query: 156 -KIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 ++G IP+ GD F +T+ P+GVC I WN+P + WK APAL GN +V KP+E Sbjct: 130 SALNGDYIPLGGD-FAYTKRVPLGVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSEN 188 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 TPL AL + ++ EAG P G+ N++ G G + +H + K++ TGS G+ + A Sbjct: 189 TPLGALKIAEILIEAGLPKGLFNVIQGD-RDTGPLLVNHPDVAKVSLTGSVPTGRKVAAA 247 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 A +LK VT+ELGGKSP I+F DAD++ AV A G F++ GQ C+ G+R+FV++ Sbjct: 248 AAG-HLKHVTMELGGKSPMIVFDDADIESAVGGAMLGNFYSSGQVCSNGTRVFVQKKAKA 306 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK---G 391 F+ R + ++G P D T GP + K Q K+L I+ G AEGA L GG Sbjct: 307 RFLENLKRRTEAMILGDPLDYATHLGPLVSKAQQEKVLSYIEKGKAEGATLITGGGIPNN 366 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 + +G +++PTVF++VTDDM IA+EEIFGPV +L F DEV+ RAN ++FGL VFT Sbjct: 367 VAGEGAYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDDEDEVLARANATEFGLAGGVFT 426 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 D+ +A V ++AGT+WIN YN + PFGG K SG GRE L YSE+KTV V Sbjct: 427 ADLARAHRVVDGLEAGTLWINTYNLCPVEIPFGGSKQSGFGRENSAAALEHYSELKTVYV 486 >4V6H-A nrPDB Length = 484 Score = 539 bits (1390), Expect = e-154, Method: Composition-based stats. Identities = 176/486 (36%), Positives = 260/486 (53%), Gaps = 6/486 (1%) Query: 27 PSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARL 86 P + + + +I EWQ ++S F V++PATGE + V + A+ +A Sbjct: 2 PGSMKDPSLLRHQAYIGGEWQAADSDATFEVFDPATGESLGTVPKMGAAE---TARAIEA 58 Query: 87 AFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT 146 A + + WR A ER +L + DLV + LA + + GKP +A ++ Sbjct: 59 AQAAWAGWRMKTAKERAAILRRWFDLVIANSDDLALILTTEQGKPLAEA-KGEIAYAASF 117 Query: 147 FRYYAGWADKIHGMTIPV-DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGN 205 ++A ++ G T+P D + EPIGVC I PWNFP M A K+ PAL G Sbjct: 118 IEWFAEEGKRVAGDTLPTPDANKRIVVVKEPIGVCAAITPWNFPAAMIARKVGPALAAGC 177 Query: 206 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 +V+KPAE TP SAL M L + AG P GV++++ G G I S+ + K++FTGST Sbjct: 178 PIVVKPAESTPFSALAMAFLAERAGVPKGVLSVVIGDPKAIGTEITSNPIVRKLSFTGST 237 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 VG+L+ + +K++TLELGG +P I+F DADLD AVE A + N GQ C +R Sbjct: 238 AVGRLLMAQSA-PTVKKLTLELGGNAPFIVFDDADLDAAVEGAIASKYRNNGQTCVCTNR 296 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 FV E +Y+ F + + VG + GP I++ K+ I +A+GA L Sbjct: 297 FFVHERVYDAFADKLAAAVSKLKVGRGTESGATLGPLINEAAVKKVESHIADALAKGASL 356 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445 GGK F EPTV + V DM +AKEE FGP+ + RF + +E++ AN+++FGL Sbjct: 357 MTGGKRHALGHGFFEPTVLTGVKPDMDVAKEETFGPLAPLFRFASEEELVRLANDTEFGL 416 Query: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 A +++ DI + V+ A++ G V IN N +PFGG K SG GRE +G+ +Y Sbjct: 417 AAYLYSRDIGRVWRVAEALEYGMVGINTGLISNEVAPFGGVKQSGLGREGSHYGIDDYVV 476 Query: 506 VKTVTV 511 +K + V Sbjct: 477 IKYLCV 482 >5KLK-A nrPDB Length = 520 Score = 539 bits (1389), Expect = e-153, Method: Composition-based stats. Identities = 177/484 (36%), Positives = 268/484 (55%), Gaps = 15/484 (3%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 +I+ + S S F NP G+ + +V EAD +++AV AA+ A W ++ Sbjct: 42 NYIDGNFVTSAS--SFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKG--PWGKLSV 97 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADK--- 156 +R L+ K+AD ++ E + G+P QA +D+ I FR +A A Sbjct: 98 QDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHT 157 Query: 157 -IHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 + M+ +T +P+GV G I PW+ PLL+F WK+APAL CGNTVV KP+E++ Sbjct: 158 DLFEMSTSDGSGALNYTVRKPLGVIGVISPWDLPLLLFTWKVAPALACGNTVVAKPSEES 217 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPT-AGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 P SA + ++ +AG PPGV N++ G+G AG + H GI + FTG ++ G I +A Sbjct: 218 PSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKA 277 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 +K V+ ELGGK+ ++FADADLD A+E + F N GQ C R++V SI++ Sbjct: 278 VA-DGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFD 336 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG- 393 EFV A+R VVG P GP I +K+L + V EGA + GG Sbjct: 337 EFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKF 396 Query: 394 ----RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 +G +++PT+++ ++D R EEIFGPV I F DEVI R N+S++GL A+ Sbjct: 397 NDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAI 456 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 +T ++++A VS + G VW+N + + ++PFGG K+SG GRE G F + YS++ + Sbjct: 457 WTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANI 516 Query: 510 TVKI 513 +KI Sbjct: 517 CIKI 520 >5J77-A nrPDB Length = 508 Score = 537 bits (1385), Expect = e-153, Method: Composition-based stats. Identities = 163/487 (33%), Positives = 268/487 (55%), Gaps = 13/487 (2%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 TK++I+ +W NS SG+ Y+P TG+ + ++ A + D+D+A+ AA AF W Sbjct: 1 MDTKLYIDGQWVNSSSGKTVDKYSPVTGQVIGRMEAATRDDVDRAIDAAEDAFW---AWN 57 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 + + ER +++ + +L+E++RA L + GKP +A ++ GVI +YYA WA Sbjct: 58 DLGSVERSKIIYRAKELIEKNRAELENIIMEENGKPVKEA-KEEVDGVIDQIQYYAEWAR 116 Query: 156 KIHGMTIPVDGDYFTFTRHE-PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 K++G + + +++ P G+ + PWNFP M A K+APAL GNTVV+KP+ Sbjct: 117 KLNGEVVEGTSSHRKIFQYKVPYGIVVALTPWNFPAGMVARKLAPALLTGNTVVLKPSSD 176 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 TP SA ++ EAG P GV+N + G G G I H ++ I TGST G+ I + Sbjct: 177 TPGSAEWIVRKFVEAGVPKGVLNFITGRGSEIGDYIVEHKKVNLITMTGSTATGQRIMQK 236 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 A +N+ ++ LELGGK+P +++ DAD+D A++ ++N GQ C A R++V E IY+ Sbjct: 237 AS-ANMAKLILELGGKAPFMVWKDADMDNALKTLLWAKYWNAGQSCIAAERLYVHEDIYD 295 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG- 393 F+ R VE +++ +G P + GP I+K E+++ GAK+ GG Sbjct: 296 TFMSRFVELSRKLALGDP--KNADMGPLINKGALQATSEIVEEAKESGAKILFGGSQPSL 353 Query: 394 ----RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 R G+F PT+ N +I +EEIF PV + +++E+ + AN++ +GL + + Sbjct: 354 SGPYRNGYFFLPTIIGNADQKSKIFQEEIFAPVIGARKISSVEEMYDLANDNKYGLASYL 413 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 FT D N S ++ G +++N +Q GF+M+G E ++G+ EY ++K + Sbjct: 414 FTKDPNIIFEASERIRFGELYVNMPGPEASQGYHTGFRMTGQAGEGSKYGISEYLKLKNI 473 Query: 510 TVKIPQK 516 V K Sbjct: 474 YVDYSGK 480 >1WNB-A nrPDB Length = 495 Score = 533 bits (1373), Expect = e-152, Method: Composition-based stats. Identities = 175/476 (36%), Positives = 270/476 (56%), Gaps = 8/476 (1%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K+ IN E + E G PVYNPATG+ + E+ EA ++ A R A + + W + Sbjct: 25 KLLINGELVSGE-GEKQPVYNPATGDVLLEIAEASA---EQVDAAVRAADAAFAEWGQTT 80 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 R L KLAD++E + V A +ES N GKP AF ++ ++ FR++AG A ++ Sbjct: 81 PKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLN 140 Query: 159 GMTI-PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G+ + + R +P+GV I PWN+PL+M AWK+APAL GN VV+KP+E TPL Sbjct: 141 GLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPL 200 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 +AL + L K+ FP GV+NIL G G T G + H + ++ TGS G+ I Sbjct: 201 TALKLAELAKDI-FPAGVVNILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTA- 258 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 S++KR +ELGGK+P I+F DAD++ VE ++N GQ CTA RI+ ++ IY+ V Sbjct: 259 SSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLV 318 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLGRKG 396 + G+P D +TE GP ++ + ++ A G K+ GG+ G Sbjct: 319 EKLGAAVATLKSGAPDDESTELGPLSSLAHLERVGKAVEEAKATGHIKVITGGEKRKGNG 378 Query: 397 FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINK 456 ++ PT+ + D I ++E+FGPV + F ++V+ AN+S +GL ++V+T D+ + Sbjct: 379 YYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKDVGR 438 Query: 457 ALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 A VS+ +Q G W+N + L ++ P GG K+SG G++M +GL +Y+ V+ V VK Sbjct: 439 AHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVK 494 >6C43-A nrPDB Length = 477 Score = 528 bits (1360), Expect = e-150, Method: Composition-based stats. Identities = 177/479 (36%), Positives = 263/479 (54%), Gaps = 8/479 (1%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 ++ IN + E G VYNPATGE + E+ EA A +D AVQAA AF+ W Sbjct: 4 MQYQLLINGVLVDGE-GERQSVYNPATGEVILEIAEASPAQVDAAVQAADNAFA---EWG 59 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 + R L KLAD +E++ A +ES N GKP ++ ++ FR++AG A Sbjct: 60 QTTPKARAECLLKLADSIEQNALEFARLESQNCGKPLHCVINDEIPAIVDVFRFFAGAAR 119 Query: 156 KIHGMTI-PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 + G+ + + R +PIGV I PWN+PL+M AWK+APAL GN VVIKP+E Sbjct: 120 CLSGLAAGEYLEGHTSMIRRDPIGVVASIAPWNYPLMMAAWKLAPALAAGNCVVIKPSEI 179 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 TPL+AL + L K+ FPPGV+N+L G G T G + H + ++ TGS G+ I Sbjct: 180 TPLTALKLAVLAKDI-FPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGEHILRH 238 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 +KR +ELGGK+P I+F DADLD + F+N GQ CTA RI+ + IY+ Sbjct: 239 TA-PAIKRTHMELGGKAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAACRIYAQRGIYD 297 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVA-EGAKLECGGKGLG 393 V + +G+P D +TE GP ++ ++ A ++ GG Sbjct: 298 ALVEKLGNAVSSLKMGAPEDESTELGPLSSLAHLKRVTAAVEEAKALSHIRVITGGSQTE 357 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 KG++ PT+ ++ + I + E+FGPV I F D+V+ AN+S +GL ++V+T D Sbjct: 358 GKGYYFAPTLLADAKQEDAIVQREVFGPVVSITVFDDEDQVLRWANDSRYGLASSVWTQD 417 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + +A +S+ +Q G WIN + L ++ P GG K SG G++M +GL +Y+ V+ + VK Sbjct: 418 VGRAHRLSARLQYGCTWINTHFMLVSEMPHGGQKQSGYGKDMSLYGLEDYTLVRHIMVK 476 >3I44-A nrPDB Length = 497 Score = 527 bits (1358), Expect = e-150, Method: Composition-based stats. Identities = 170/490 (34%), Positives = 270/490 (55%), Gaps = 9/490 (1%) Query: 23 LHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQ 82 + P + K +IN W + + V +P+T E + D DKA+ Sbjct: 11 TLEAQTQGPGSMLNKRKFYINGLWDDPSTPHDLYVIDPSTEEACAVISLGSTRDADKAIN 70 Query: 83 AARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQG 142 AA+ AF W+ ER ++K+ ++ E+ + +A S+ G P A Sbjct: 71 AAKKAFQ---TWKTTSPHERLGFVEKILEIYEKRSSDMAKTISMEMGAPIDMALNAQTAT 127 Query: 143 VIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALC 202 R + + ++G+ ++ IGV G I PWN+P+ K+ PAL Sbjct: 128 GSSHIRNFIKAYKEFSFQEALIEGNEQAILHYDAIGVVGLITPWNWPMNQVTLKVIPALL 187 Query: 203 CGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFT 262 G T+V+KP+E PLSA+ ++ EA P GV N++ G G G+ +++H ++ I+FT Sbjct: 188 AGCTMVLKPSEIAPLSAMLFAEILDEAALPSGVFNLINGDGANVGSYLSAHPDLEMISFT 247 Query: 263 GSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTA 322 GST GK I + A + LKRV LELGGK NIIFADAD+D A+++ + F+N GQ C A Sbjct: 248 GSTRAGKDISKNASNT-LKRVCLELGGKGANIIFADADID-ALQRGVRHCFYNSGQSCNA 305 Query: 323 GSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEG 382 +R+ VE++IY++ ++ + + A++ VG GP + K+QY+KI +LIQSG+ EG Sbjct: 306 PTRMLVEQAIYDKAIKTAKDIAEKTQVGPGHQTGNHIGPVVSKEQYDKIQDLIQSGIDEG 365 Query: 383 AKLECGGKGLG---RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERAN 439 A L GG GL +G+++ PTVF++V MRI +EEIFGPV +L F T DE + AN Sbjct: 366 ATLVTGGTGLPMGMERGYYVRPTVFADVKPHMRIFREEIFGPVLSLLPFNTEDEAVTLAN 425 Query: 440 NSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFG 499 ++++GL + + D +K +++ +++G V +N + L S FGG K SG RE G +G Sbjct: 426 DTEYGLTNYIQSQDRSKCRRIAAQVRSGMVEVNGHE-LPGGSYFGGVKFSGRAREGGLWG 484 Query: 500 LREYSEVKTV 509 ++E+ + K + Sbjct: 485 IKEFLDTKAI 494 >3TY7-A nrPDB Length = 478 Score = 527 bits (1357), Expect = e-150, Method: Composition-based stats. Identities = 177/481 (36%), Positives = 255/481 (53%), Gaps = 12/481 (2%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 N YTK +IN EW S S V NPAT E + +V + +KAD+DKAV+AA + Sbjct: 2 NAMRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADDVYL-- 59 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 +R ER LLDK+ E + + + G P + V Q + F Sbjct: 60 -EFRHTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQMGLNHFVAAR 118 Query: 152 GWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 D D E IGV G I PWNFP + K+A A G+ VV+KP Sbjct: 119 DALDNYEFEERRGD----DLVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKP 174 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 +E+TP +A+ + + + G P GV N++ G G G ++ H + ++FTGS G I Sbjct: 175 SEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKI 234 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331 E A + + K+V+LELGGKSP I+ D D+ A + V N GQ CTAG+R+ V Sbjct: 235 MEKAAK-DFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNK 293 Query: 332 IYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG 391 I + F+ E+ + VG+P + T+ GP I KKQ++++ I G+ EGA+L GG G Sbjct: 294 IKDAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPG 353 Query: 392 LG---RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 KG+F PT+F NV + M IA+EEIFGPV ++ + +DE I+ AN++ +GL Sbjct: 354 KPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGY 413 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 V D V+ +++AGTV IN PFGG+K SG GRE G++G+ E+ EVK+ Sbjct: 414 VIGKDKETLHKVARSIEAGTVEINE-AGRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKS 472 Query: 509 V 509 + Sbjct: 473 I 473 >3U4J-A nrPDB Length = 528 Score = 526 bits (1355), Expect = e-149, Method: Composition-based stats. Identities = 201/502 (40%), Positives = 289/502 (57%), Gaps = 8/502 (1%) Query: 19 LMASLHLLP-SPTPNLEIKYT-KIFINNEWQNSESGRVFPVYNPAT-GEQVCEVQEADKA 75 +M S + P S P L IK ++ ++ + ++ SG +P GE V EA Sbjct: 2 VMLSNFIAPDSNDPRLRIKSRYQMLVDGKSVDAASGSTIDRVSPGHAGEVVGTWPEASAD 61 Query: 76 DIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQA 135 D+ KAV AAR AF G W RM +ER RL+ K+ADL+ + LA +ESL GKP QA Sbjct: 62 DVRKAVAAARKAFDAGP-WPRMSGAERSRLMFKVADLILARQEELALIESLEVGKPIAQA 120 Query: 136 FYVDLQGVIKTFRYYAGWADKIHGMTIP-VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFA 194 ++ + Y AG A + G T + D EP+GV G I PWNFP ++ + Sbjct: 121 -RGEIGFCADLWSYAAGQARALEGQTHNNIGDDRLGLVLREPVGVVGIITPWNFPFIIAS 179 Query: 195 WKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHI 254 ++ A+ G TVV+KP+E T +++ + L +EAG P GV N++ GYG AG +A Sbjct: 180 ERVPWAIGSGCTVVLKPSEFTSGTSIRLAELAREAGIPDGVFNVVTGYGDPAGQVLAEDP 239 Query: 255 GIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFF 314 +D +AFTGS VG + E A R+ +KRV LELGGK P I+FADADLD A + GV+ Sbjct: 240 NVDMVAFTGSVRVGTKLGEIAART-VKRVGLELGGKGPQIVFADADLDAAADGIAYGVYH 298 Query: 315 NQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILEL 374 N GQCC +GSR+ V+E I + + R ++ +++ G P + T+ G I + K+ Sbjct: 299 NAGQCCISGSRLLVQEGIRDALMERLLDISRKVAFGDPLNERTKIGAMISEAHAEKVHSY 358 Query: 375 IQSGVAEGAKLECGGKGLGRK-GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDE 433 + +G+ GA+L GG+ +GR+ G + PTVF+ VT DM IA+EEIFGPV L FKT DE Sbjct: 359 VTAGITSGAELLLGGERIGREAGLYYAPTVFAGVTPDMSIAREEIFGPVLSTLTFKTADE 418 Query: 434 VIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGR 493 + AN ++FGL A+V++ ++ AL ++AG WIN + P GG+K SG GR Sbjct: 419 AVALANATEFGLSASVWSTNLETALQTIRRIRAGRCWINSVIDGTPELPIGGYKKSGLGR 478 Query: 494 EMGEFGLREYSEVKTVTVKIPQ 515 E+G +G EYS+ K V V + + Sbjct: 479 ELGRYGFDEYSQFKGVHVTLGR 500 >3EK1-A nrPDB Length = 504 Score = 523 bits (1347), Expect = e-149, Method: Composition-based stats. Identities = 178/482 (36%), Positives = 268/482 (55%), Gaps = 8/482 (1%) Query: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89 + + ++ +N W ++ G V NPA G + V A I +A+ A+ A S Sbjct: 25 LKDPSLLKSQCLVNGRWIDAADGTTIKVTNPADGSVIGTVPSLSVATIKEAIDASAKALS 84 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 W A ER +L K DL+ + +A + + GKP +A ++ + Sbjct: 85 G---WAAKTAKERAGILRKWFDLIIANADDIALIMTSEQGKPLAEA-RGEVLYAASFIEW 140 Query: 150 YAGWADKIHGMTIPVDGDYFTFTR-HEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 +A A +++G TIP + T +P+GV I PWNFP M K APAL G T++ Sbjct: 141 FAEEAKRVYGDTIPAPQNGQRLTVIRQPVGVTAAITPWNFPAAMITRKAAPALAAGCTMI 200 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 ++PA+ TPL+AL +G L ++AG P GV+ I+ G GA + S+ + K++FTGSTEVG Sbjct: 201 VRPADLTPLTALALGVLAEKAGIPAGVLQIVTGKAREIGAELTSNDTVRKLSFTGSTEVG 260 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 +L+ +KR++LELGG +P I+F DADLD AV+ A + N GQ C +RI+V Sbjct: 261 RLLMAQCA-PTIKRISLELGGNAPFIVFDDADLDAAVDGAMVSKYRNAGQTCVCANRIYV 319 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 + +Y++F + + K VG+ +P GP I++K K+ I+ V++GAKL G Sbjct: 320 QRGVYDKFAEKLAAKVKELKVGNGTEPGVVIGPMIEEKAITKVKAHIEDAVSKGAKLITG 379 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 GK LG G F EP + + VT DM +AKEE FGP+ + F T +EVI +AN++ FGL A Sbjct: 380 GKELG--GLFFEPGILTGVTSDMLVAKEETFGPLAPLFAFDTEEEVIAQANDTIFGLAAY 437 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 +T + ++A+ VS A++ G V N N +PFGG K SG GRE ++G+ EY E K Sbjct: 438 FYTENFSRAIRVSEALEYGMVGHNTGLISNEVAPFGGVKQSGLGREGSKYGIEEYLETKY 497 Query: 509 VT 510 + Sbjct: 498 IC 499 >4LIH-A nrPDB Length = 504 Score = 522 bits (1344), Expect = e-148, Method: Composition-based stats. Identities = 202/486 (41%), Positives = 297/486 (61%), Gaps = 9/486 (1%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 +LEI+ + FI+ +++ GR F +P G + +V + +AD++ AV AAR AF G Sbjct: 23 SLEIEG-RAFIDGASRDAHGGRTFDCVSPIDGRVLAKVADCGEADVNAAVAAARRAFDAG 81 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 VW ++ R +L + A L+ L+ +E+L+ GKP VD+ G ++A Sbjct: 82 -VWAGLNPRARKAVLLRWAALMREHLDELSLLETLDAGKPIGDTTTVDVPGAAYCVEWFA 140 Query: 152 GWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKP 211 DK+ G P D EP+GV ++PWNFP+LM AWK PAL GN+VV+KP Sbjct: 141 EAIDKVGGEVAPADHHLVGLVTREPVGVVAAVVPWNFPILMAAWKFGPALAAGNSVVLKP 200 Query: 212 AEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI 271 +E++PL+A+ + L EAG P GV N++PG G G +A H +D IAFTGST VGKLI Sbjct: 201 SEKSPLTAIRVAQLAFEAGIPAGVFNVVPGAG-EPGKLLALHRDVDCIAFTGSTAVGKLI 259 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 + A +SNLKR LELGGKSPNI+ D DLD A + A +F+N G+ CTAGSR+ V Sbjct: 260 MQYAAQSNLKRAWLELGGKSPNIVLPDCPDLDRAAQTAAGAIFYNMGEMCTAGSRLLVHR 319 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 I + F+ + V A+ V G+P DP+ G +D Q ++L I++G EG +L GG Sbjct: 320 DIKDAFIEKLVAAARAYVPGNPLDPSVSMGAIVDGIQLERVLGYIEAGRGEG-RLVTGGA 378 Query: 391 GLGRK--GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 + + GF++EPTVF V D +IA+EEIFGPV ++ F +DE + AN++++GL AA Sbjct: 379 RVNAETGGFYVEPTVFE-VKPDAKIAREEIFGPVLSVIVFDDVDEAVRIANDTEYGLAAA 437 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYN-ALNAQSPFGGFKMSGNGREMGEFGLREYSEVK 507 V+T+++ A VS ++AGTVW+NCY+ + PFGG+K SGNGR+ L +Y+E+K Sbjct: 438 VWTSNLTTAHDVSRRLRAGTVWVNCYDEGGDMNFPFGGYKQSGNGRDKSLHALEKYTELK 497 Query: 508 TVTVKI 513 + +++ Sbjct: 498 STLIRL 503 >4U3W-A nrPDB Length = 505 Score = 521 bits (1343), Expect = e-148, Method: Composition-based stats. Identities = 182/485 (37%), Positives = 260/485 (53%), Gaps = 15/485 (3%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + +IN E+ SG FP +P G ++ +V EAD A +D AVQAA A G WR Sbjct: 25 RHYINGEFV--ASGTTFPNLSPVDGRKLADVCEADAALVDSAVQAAHAAQKAG--WRDTT 80 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ++R L K+AD +E E + G+P QA +D+ I FR +A Sbjct: 81 PAQRAAWLHKIADGIEARFDEFVAAEVADTGRPVAQARTLDIARGIANFRTFADLVRTAS 140 Query: 159 GM----TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 G + + +P+GV G I PWN PLL+F WK+APAL GN VV KP+E+ Sbjct: 141 GEYFETHAADGSELINYVTRKPLGVIGIISPWNLPLLLFTWKVAPALAMGNCVVAKPSEE 200 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGP-TAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 TP SA + ++ + G PPGV N++ G+G AG + H I I FTG + G I + Sbjct: 201 TPSSATLLAEVMHDVGLPPGVFNLIHGHGQNAAGEFLTRHPDISAITFTGESRTGSTIMK 260 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 A +K V+ ELGGK+ ++FADAD D AV + F N GQ C R++VE I+ Sbjct: 261 AVA-DGVKEVSFELGGKNAAVVFADADFDAAVAGVLRSSFTNAGQVCLCSERVYVERPIF 319 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 E FV E+A+ VG+P DP T GP I + +K+L + V EGA + GG Sbjct: 320 ERFVAALKEQAQALRVGAPEDPATTMGPLISRGHRDKVLSYFRLAVEEGATVVTGGGAPS 379 Query: 394 -----RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448 G F+ PT+++ + D R +EEIFGPV I F EV++R N+S +GL A+ Sbjct: 380 FGDARDDGAFVMPTIWTGLPDSARCVREEIFGPVCHIAPFDDEAEVVKRVNDSAYGLAAS 439 Query: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 ++T + + V+ ++ G VW+N + + ++PFGG K+SG GRE G L YSE+ Sbjct: 440 IWTTQLARGHRVAKQIETGIVWVNAWFVRDLRTPFGGTKLSGLGREGGRHSLDFYSELTN 499 Query: 509 VTVKI 513 V V+I Sbjct: 500 VCVRI 504 >3K2W-A nrPDB Length = 497 Score = 516 bits (1330), Expect = e-147, Method: Composition-based stats. Identities = 162/488 (33%), Positives = 245/488 (50%), Gaps = 10/488 (2%) Query: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89 +L K FI ++ S + +P+TG+ + E+ KAD + A++ A+ A Sbjct: 5 VQDLHFKNKVNFIGGQYVPSNESDTIDILSPSTGKVIGEIPAGCKADAENALEVAQAAQK 64 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 + + A R +L A+ + ++ +LA M GK A +++ Y Sbjct: 65 AWAK---LTARTRQNMLRTFANKIRENKHILAPMLVAEQGKLLSVAE-MEVDVTATFIDY 120 Query: 150 YAGWADKIHGMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 A I G +P D D + P GV I WNFPL + KI PAL GNT+V Sbjct: 121 GCDNALTIEGDILPSDNQDEKIYIHKVPRGVVVGITAWNFPLALAGRKIGPALITGNTMV 180 Query: 209 IKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG 268 +KP ++TPL+ +G + KEAG P GV+N++ G G G + I TGST G Sbjct: 181 LKPTQETPLATTELGRIAKEAGLPDGVLNVINGTGSVVGQTLCESPITKMITMTGSTVAG 240 Query: 269 KLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV 328 K I + + + V LELGGK+P ++ DADLD A E A G F N GQ CT R++V Sbjct: 241 KQIYKTSAEY-MTPVMLELGGKAPMVVMDDADLDKAAEDALWGRFANCGQVCTCVERLYV 299 Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECG 388 S+Y+EF+ + + K VG P D ++ GP+ ++++ + I ++ + +GA + G Sbjct: 300 HASVYDEFMAKFLPLVKGLKVGDPMDADSQMGPKCNQREIDNIDHIVHEAIKQGATVATG 359 Query: 389 GKGLGRKGF----FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG 444 GK +GF + EPTV +V D + EE FGP+ I++ +M++ IE N+S +G Sbjct: 360 GKTATVEGFEGGCWYEPTVLVDVKQDNIVVHEETFGPILPIVKVSSMEQAIEFCNDSIYG 419 Query: 445 LVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYS 504 L A V T S ++ G V+IN Q G+K SG G E G+FGL +Y Sbjct: 420 LSAYVHTQSFANINQAISDLEVGEVYINRGMGEQHQGFHNGWKQSGFGGEDGKFGLEQYL 479 Query: 505 EVKTVTVK 512 E KTV + Sbjct: 480 EKKTVYIN 487 >2HG2-A nrPDB Length = 479 Score = 515 bits (1328), Expect = e-146, Method: Composition-based stats. Identities = 152/475 (32%), Positives = 243/475 (51%), Gaps = 7/475 (1%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 ++I+ ++ V NPAT + + + D KA+ AA A W + A Sbjct: 9 MYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERA---QPEWEALPA 65 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 ER L K++ + + ++ + GGK Q V++ Y A WA + G Sbjct: 66 IERASWLRKISAGIRERASEISALIVEEGGK-IQQLAEVEVAFTADYIDYMAEWARRYEG 124 Query: 160 MTIPVDGDYFTFTR-HEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 I D +GV I+PWNFP + A K+APAL GNT+VIKP+E TP + Sbjct: 125 EIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFTPNN 184 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 A+ ++ E G P GV N++ G G T G +A + + ++ TGS G+ I A + Sbjct: 185 AIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMATAAK- 243 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 N+ +V LELGGK+P I+ DADL+ AV+ N GQ C R++V++ IY++FV Sbjct: 244 NITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQFVN 303 Query: 339 RSVERAKRRVVGSPFDP-TTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 397 R E + G+P + GP I+ ++ + + V EGA++ GGK + KG+ Sbjct: 304 RLGEAMQAVQFGNPAERNDIAMGPLINAAALERVEQKVARAVEEGARVAFGGKAVEGKGY 363 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457 + PT+ +V +M I EE FGPV ++ F T+++ I AN+SD+GL ++++T ++N A Sbjct: 364 YYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDAISMANDSDYGLTSSIYTQNLNVA 423 Query: 458 LTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + ++ G +IN N Q G++ SG G G+ GL EY + + V ++ Sbjct: 424 MKAIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLHEYLQTQVVYLQ 478 >4F3X-A nrPDB Length = 498 Score = 514 bits (1325), Expect = e-146, Method: Composition-based stats. Identities = 170/480 (35%), Positives = 266/480 (55%), Gaps = 8/480 (1%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 + T++ I + + + + + NP TG + ++ EA A ID AV AA AF W Sbjct: 23 MMDTQLLIGSRF-EAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAFVG---W 78 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 + +ER L K+AD +E++ A +E+LN GKP +L +I +R++AG Sbjct: 79 SQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAV 138 Query: 155 DKIHGMTI-PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 +H + + R +PIG+ G I PWN+PL+M AWK+APA+ GNTVV KP+E Sbjct: 139 RNLHAPAAGEYLPGHTSMIRRDPIGIVGSIAPWNYPLMMMAWKLAPAIGGGNTVVFKPSE 198 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 QTPL+AL + LI + P GV+N++ G G T G A+ +H + ++ TG GK + Sbjct: 199 QTPLTALKLARLIADI-LPEGVVNVITGRGETVGNALINHPKVGMVSITGDIATGKKVLA 257 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 AA ++ +KR LELGGK+P I++ DADL+ V ++N GQ CTA RI+ E IY Sbjct: 258 AAAKT-VKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIY 316 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGL 392 E+ V D E GP I ++Q +++ ++ + ++ GG+ Sbjct: 317 EKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTG 376 Query: 393 GRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452 +GFF +PTV + T + I + E+FGPV + RF D+ + AN+SD+GL ++V+T Sbjct: 377 SDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTK 436 Query: 453 DINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 DI+KA+ +S +Q G WIN + L + P GG K SG G++M + L +Y+ V+ + + Sbjct: 437 DISKAMRAASRLQYGCTWINTHFMLTNEMPHGGIKQSGYGKDMSVYALEDYTAVRHIMIN 496 >1T90-A nrPDB Length = 486 Score = 507 bits (1305), Expect = e-144, Method: Composition-based stats. Identities = 163/489 (33%), Positives = 248/489 (50%), Gaps = 11/489 (2%) Query: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93 EI+ K +IN EW S++ + V NPAT E +C+V + K DID A Q A AF Sbjct: 2 EIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAF---KT 58 Query: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153 W ++ R R+L L+ + + LA + ++ GK +A ++ I+ + AG Sbjct: 59 WSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEAL-GEVGRGIENVEFAAGA 117 Query: 154 ADKIHGMTI-PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPA 212 + G ++ + D PIGV G I P+NFP+++ W A+ GNT ++KP+ Sbjct: 118 PSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPS 177 Query: 213 EQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQ 272 E+TPL + L ++AG P GV N++ G I H I I+F GS VG+ + Sbjct: 178 ERTPLLTEKLVELFEKAGLPKGVFNVVYGA-HDVVNGILEHPEIKAISFVGSKPVGEYVY 236 Query: 273 EAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESI 332 + G NLKRV G K+ I+ DA+L+ V F + G+ C A + + VEE I Sbjct: 237 KK-GSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGI 295 Query: 333 YEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG- 391 +EF+ + E+ +G+ D GP I + + L I+ G+ EGA+L C G+ Sbjct: 296 ADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKRTLSYIEKGLEEGARLVCDGREN 355 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 + G+F+ PT+F NVT +M I K+EIF PV ++R K + E IE AN S+F A +FT Sbjct: 356 VSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKNLKEAIEIANKSEFANGACLFT 415 Query: 452 NDINKALTVSSAMQAGTVWIN-CYNALNAQSPFGGFKMS--GNGREMGEFGLREYSEVKT 508 ++ N + AG + IN A A PF G+K S G G+ + Y+ K Sbjct: 416 SNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFFGTLHANGKDSVDFYTRKKV 475 Query: 509 VTVKIPQKN 517 VT + P + Sbjct: 476 VTARYPAPD 484 >5EUY-A nrPDB Length = 491 Score = 503 bits (1295), Expect = e-143, Method: Composition-based stats. Identities = 157/485 (32%), Positives = 250/485 (51%), Gaps = 11/485 (2%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 +L I +IN E++ +G +P G ++ EV + + D +A+ + AF Sbjct: 3 DLNIMKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDS---AFEAL 59 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 W + A R L K+ ++ + + + ++ GG + + + ++ + + A Sbjct: 60 KAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVW-GEVVFTERLIQNAA 118 Query: 152 GWADKIHGMTIPVDGDYF-TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 A G + D + + GV G I PWN+PL + KIA L GNTVV K Sbjct: 119 ELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYK 178 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 PA TP++ + ++ +AG P GV N++ G GP G I +H + + FTG + G+ Sbjct: 179 PASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGRE 238 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 I A + LK VTLELGG P II D D+DYA A F+QGQ CT+ RI V + Sbjct: 239 IAAKAAGT-LKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHK 297 Query: 331 SIYEEFVRRSVERAKRRVVGSPF-DPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 ++ ++F+ R V K + P D + GP I+++Q + E + V+ G +L GG Sbjct: 298 AVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGG 357 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 + G F EP +F +V + RI +EE+FGPV+ I+ + D+ +E AN++D+GL AV Sbjct: 358 RSW---GNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAV 414 Query: 450 FTNDINKALTVSSAMQAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508 TN++N+A ++ A+++G IN + PFGG K SG GRE GE+ E + + Sbjct: 415 LTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRW 474 Query: 509 VTVKI 513 VTV + Sbjct: 475 VTVTL 479 >3QAN-A nrPDB Length = 538 Score = 502 bits (1292), Expect = e-142, Method: Composition-based stats. Identities = 171/508 (33%), Positives = 252/508 (49%), Gaps = 21/508 (4%) Query: 12 VKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPAT-GEQVCEVQ 70 V+A+ A +L L+ K + IN E +E +NPA + V V Sbjct: 16 VEANRKAFEEALGLVEKELG----KEYPLIINGERVTTED--KIQSWNPARKDQLVGSVS 69 Query: 71 EADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGK 130 +A++ +KA+Q+A AF WR ++ ER +L K A ++ R + + GK Sbjct: 70 KANQDLAEKAIQSADEAFQ---TWRNVNPEERANILVKAAAIIRRRKHEFSAWLVHEAGK 126 Query: 131 PFLQAFYVDLQGVIKTFRYYAGWADKIH-GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFP 189 P+ +A D I YYA +++ G I + P+GV I PWNF Sbjct: 127 PWKEA-DADTAEAIDFLEYYARQMIELNRGKEILSRPGEQNRYFYTPMGVTVTISPWNFA 185 Query: 190 LLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAA 249 L + + GNTVV+KPA TP+ A ++++AG P GVIN +PG G G Sbjct: 186 LAIMVGTAVAPIVTGNTVVLKPASTTPVVAAKFVEVLEDAGLPKGVINYVPGSGAEVGDY 245 Query: 250 IASHIGIDKIAFTGSTEVGKLIQEAA-----GRSNLKRVTLELGGKSPNIIFADADLDYA 304 + H I FTGS +VG + E A G+++LKRV +E+GGK ++ DADLD A Sbjct: 246 LVDHPKTSLITFTGSKDVGVRLYERAAVVRPGQNHLKRVIVEMGGKDTVVVDRDADLDLA 305 Query: 305 VEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQID 364 E F GQ C+AGSR + + +Y+E + ++V AK VG P + GP ID Sbjct: 306 AESILVSAFGFSGQKCSAGSRAVIHKDVYDEVLEKTVALAKNLTVGDPTNRDNYMGPVID 365 Query: 365 KKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQE 424 +K + KI+ I+ G EG +L GG+G GFFI+PT+ +++ + I +EEIFGPV Sbjct: 366 EKAFEKIMSYIEIGKKEG-RLMTGGEGDSSTGFFIQPTIIADLDPEAVIMQEEIFGPVVA 424 Query: 425 ILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWI--NCYNALNAQSP 482 + D +E ANN+++GL AV T + G ++ NC A+ P Sbjct: 425 FSKANDFDHALEIANNTEYGLTGAVITRNRAHIEQAKREFHVGNLYFNRNCTGAIVGYHP 484 Query: 483 FGGFKMSGNGRE-MGEFGLREYSEVKTV 509 FGGFKMSG + G L + + KTV Sbjct: 485 FGGFKMSGTDSKAGGPDYLALHMQAKTV 512 >5X5U-A nrPDB Length = 505 Score = 501 bits (1291), Expect = e-142, Method: Composition-based stats. Identities = 161/481 (33%), Positives = 240/481 (49%), Gaps = 6/481 (1%) Query: 32 NLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91 N+ T++ I+ EW ++ SG+ V NPATG+ + V A AD+D+A+ AA+ F Sbjct: 27 NVTYTDTQLLIDGEWVDAASGKTIDVVNPATGKPIGRVAHAGIADLDRALAAAQSGFE-- 84 Query: 92 SVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYA 151 WR++ A ER + K A LV +A + + GKP +A V++ ++A Sbjct: 85 -AWRKVPAHERAATMRKAAALVRERADAIAQLMTQEQGKPLTEA-RVEVLSAADIIEWFA 142 Query: 152 GWADKIHGMTIPVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 +++G +P EP+G PWNFP+ K++ AL G + ++K Sbjct: 143 DEGRRVYGRIVPPRNLGAQQTVVKEPVGPVAAFTPWNFPVNQVVRKLSAALATGCSFLVK 202 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 E+TP S + +AG P GVI ++ G + + H I K+ FTGST VGK Sbjct: 203 APEETPASPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQ 262 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 + AG ++KR T+ELGG +P I+ DAD+ AV+ A F N GQ C + +R V Sbjct: 263 LASLAG-LHMKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLVHN 321 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 SI +EF R V+ A+ VG+ + T G + ++ + +I + GA +E GG+ Sbjct: 322 SIRDEFTRALVKHAEGLKVGNGLEEGTTLGALANPRRLTAMASVIDNARKVGASIETGGE 381 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 +G +G F PTV +NV D + E FGPV I F ++E I AN FGL F Sbjct: 382 RIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKLEEAIAEANRLPFGLAGYAF 441 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 T ++ ++ G +WIN + PFGG K SG G E G L Y K+VT Sbjct: 442 TRSFANVHLLTQRLEVGMLWINQPATPWPEMPFGGVKDSGYGSEGGPEALEPYLVTKSVT 501 Query: 511 V 511 V Sbjct: 502 V 502 >3B4W-A nrPDB Length = 495 Score = 500 bits (1288), Expect = e-142, Method: Composition-based stats. Identities = 182/487 (37%), Positives = 257/487 (52%), Gaps = 6/487 (1%) Query: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89 + +Y K+FI +W + V V PATGE V +V A AD+D AV AAR AF Sbjct: 1 MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAADVDAAVAAARAAFD 60 Query: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149 G W ER ++ ++ + + + + G+P + G + Y Sbjct: 61 NGP-WPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPPTIIETMHWMGSMGAMNY 119 Query: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 +AG ADK+ + EP+GV G I+ WN PL + KIAPAL G T+V+ Sbjct: 120 FAGAADKVTWTETRTGSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVL 179 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KPA +TPL+A + + E G P GV++++PG G G A+ S+ ID FTGS+ VG+ Sbjct: 180 KPAAETPLTANALAEVFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGR 238 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 + A LK TLELGGKS II D DL A+ N GQ C +RI Sbjct: 239 EVGRRAAEM-LKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQTRILAP 297 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 S Y+E V VG P DP + GP I +KQ ++ I G+ EGA+L CGG Sbjct: 298 RSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGYIAKGIEEGARLVCGG 357 Query: 390 KGLG--RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVA 447 GFFI+PTVF++V + M IA+EEIFGPV I+ + T ++ I AN+S +GL Sbjct: 358 GRPEGLDNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAG 417 Query: 448 AVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVK 507 +V+T D+ K + +S ++ GT IN Y A + SPFGG+K SG GRE G G+ +++ K Sbjct: 418 SVWTTDVPKGIKISQQIRTGTYGINWY-AFDPGSPFGGYKNSGIGRENGPEGVEHFTQQK 476 Query: 508 TVTVKIP 514 +V + + Sbjct: 477 SVLLPMG 483 >3RJL-A nrPDB Length = 538 Score = 494 bits (1273), Expect = e-140, Method: Composition-based stats. Identities = 164/480 (34%), Positives = 240/480 (50%), Gaps = 17/480 (3%) Query: 40 IFINNEWQNSESGRVFPVYNPAT-GEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + I+ E +E+ NPA E V V +A + +KA+QAA AF WR D Sbjct: 40 LVIDGERYETEN--KIVSINPANKEEVVGTVSKATQDHAEKAIQAAAKAFE---TWRYTD 94 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI- 157 ER +L + V R + + + GKP+ +A D I YYA ++ Sbjct: 95 PEERAAVLFRAVAKVRRKKHEFSALLVKEAGKPWNEA-DADTAEAIDFMEYYARQMIELA 153 Query: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G + + P GV I PWNF + A + GNTVV+KPA P+ Sbjct: 154 KGKPVNSREGERNQYVYTPTGVTVVIPPWNFLFAIMAGTTVAPIVTGNTVVLKPASAAPV 213 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA-- 275 A +++E+G P GV+N +PG G G + H I FTGS EVG I E A Sbjct: 214 IAAKFVEVLEESGLPKGVVNFVPGSGAEVGDYLVDHPKTSIITFTGSREVGTRIFERAAK 273 Query: 276 ---GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESI 332 G+++LK+V E+GGK ++ D D++ A + F GQ C+AGSR V E + Sbjct: 274 VQPGQTHLKQVIAEMGGKDTVVVDEDCDIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKV 333 Query: 333 YEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL 392 Y+E ++R +E + + VG P GP ID+ +NKI++ I+ G EG +L GGKG Sbjct: 334 YDEVLKRVIEITESKKVGEPDSADVYMGPVIDQASFNKIMDYIEIGKEEG-RLVSGGKGD 392 Query: 393 GRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452 KG+FIEPT+F+++ R+ +EEIFGPV + + DE +E ANN+++GL AV T Sbjct: 393 DSKGYFIEPTIFADLDPKARLMQEEIFGPVVAFSKVSSFDEALEVANNTEYGLTGAVITK 452 Query: 453 DINKALTVSSAMQAGTVWI--NCYNALNAQSPFGGFKMSGNGRE-MGEFGLREYSEVKTV 509 + + G ++ NC A+ PFGGFKMSG + G L + + KT+ Sbjct: 453 NRDHINRAKQEFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDYLALHMQAKTI 512 >4JZ6-A nrPDB Length = 500 Score = 492 bits (1267), Expect = e-139, Method: Composition-based stats. Identities = 183/483 (37%), Positives = 260/483 (53%), Gaps = 14/483 (2%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 TK+FINN W +S + F +P + E + E A D KA QAA AF W+ Sbjct: 18 MKTKLFINNAWIDSSDQQTFERKHPVSSEVMTESANATVTDAIKAAQAAEEAF---KTWK 74 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 + SER RLL K+AD++E + ++ G L A ++ FR A A Sbjct: 75 DVGPSERRRLLLKVADVMESKTPKFIEVMAMEVGASALWA-GFNVHASANVFREAASLAT 133 Query: 156 KIHGMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 +I G TIP D + + T +P+G I+PWN ++ A IA L CGNTVV K +E Sbjct: 134 QIQGETIPTDKAETLSMTLRQPVGPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSEF 193 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYG---PTAGAAIASHIGIDKIAFTGSTEVGKLI 271 +P + + ++EAG P GV+N L P A+ S I +I FTGST VG +I Sbjct: 194 SPATHALITQCVQEAGLPAGVLNYLNSSPDRSPEIADALISAKEIRRINFTGSTRVGSII 253 Query: 272 QEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331 + A + +LKR LELGGKSP I+ DAD++ AV+ A G F QGQ C + R+ V+E Sbjct: 254 AQKAAQ-HLKRCLLELGGKSPLIVLDDADINAAVKAAVFGSFLFQGQICMSTERLVVDEK 312 Query: 332 IYEEFVRRSVERAKRRVVGSP-FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 I +EFV R VE+ +R VG P GP + +I L + + +GAK+ CGG Sbjct: 313 IADEFVARFVEKTERLSVGDPCLTGDCIIGPMVSPNSGERINGLFKDAIDKGAKVVCGGM 372 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 +G + T+ +V DMRI EE FGP+ ++R K E I AN+S +GL + VF Sbjct: 373 A---QGAVMPATILDHVKSDMRIYDEETFGPITVVIRCKGEAEAIRIANDSVYGLSSGVF 429 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 DIN+AL V +++ G V IN N AQ+P+GG K +G GR G + E++E+K + Sbjct: 430 GRDINRALRVGMSIEYGCVHINGSTVQNEAQAPYGGTKNTGYGRFDGRAVIDEFTELKWL 489 Query: 510 TVK 512 T++ Sbjct: 490 TIE 492 >2JG7-A nrPDB Length = 510 Score = 492 bits (1267), Expect = e-139, Method: Composition-based stats. Identities = 145/480 (30%), Positives = 234/480 (48%), Gaps = 14/480 (2%) Query: 43 NNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASER 102 N W SG V Y PA E + V +A A+ ++ VQ R A+ + W + A +R Sbjct: 27 NGSW--GGSGEVITSYCPANNEPIARVTQATLAEYEETVQKTREAWKM---WADIPAPKR 81 Query: 103 GRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTI 162 G ++ ++ D + + VL ++ SL GK +++ ++Q + Y G + I G + Sbjct: 82 GEIVRQIGDALRKKIKVLGSLVSLEMGKIYVEGV-GEVQEYVDVCDYAVGLSRMIGGPVL 140 Query: 163 PVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALY 221 P + + + P+G+ G I +NFP+ ++ W A AL CGN + K A TPL+++ Sbjct: 141 PSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALTCGNVCLWKGAPTTPLTSVA 200 Query: 222 MGALIKEA---GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 + ++ E PG I + G G A+A +D ++FTGST VGK++ + Sbjct: 201 VTKIVAEVLEQNNLPGAICSMTCGGADIGTAMAKDERVDLLSFTGSTHVGKMVAMMV-QE 259 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 R LELGG + I+F DADL+ V A GQ CT R+ + ES+++ V Sbjct: 260 RFGRKLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESVHDAVVE 319 Query: 339 RSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFF 398 R + K+ +G P+DP+T GP K+ ++ L I+ +G L CGGK + R G + Sbjct: 320 RIAKAYKQVRIGDPWDPSTLYGPLHTKQAVDQYLAAIEQAKQQGGTLVCGGKVMDRPGNY 379 Query: 399 IEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKAL 458 +EPT+ + + D I E F P+ +L+FKT +E N GL +++FT D+ + Sbjct: 380 VEPTIITGLAHDAPIVHTETFVPILYVLKFKTEEEAFAWNNEVQQGLSSSIFTKDLGRVF 439 Query: 459 TV--SSAMQAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQ 515 G V +N + FGG K +G GRE G ++Y T T+ + Sbjct: 440 RWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSK 499 >2W8P-A nrPDB Length = 487 Score = 492 bits (1266), Expect = e-139, Method: Composition-based stats. Identities = 169/478 (35%), Positives = 251/478 (52%), Gaps = 12/478 (2%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 T F+ W + FPV +PA+G + V + + AV+AA AF WR + Sbjct: 13 TDSFVGGRWLPAA--ATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 67 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 A ER LL K +L+ +++ LA + + GKP +A + ++ +++ A ++ Sbjct: 68 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEA-HGEILYSAFFLEWFSEEARRV 126 Query: 158 HGMTIPVDG-DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTP 216 +G I D +PIGV I PWNFP M K+ AL G TVV+KPAE TP Sbjct: 127 YGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTP 186 Query: 217 LSALYMGALIKEAGFPPGVINILPGYGP---TAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 SAL + L +AG P GV N++P G AI + + KI+FTGST GK++ Sbjct: 187 FSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLH 246 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 A S +KRV++ELGG +P I+F A++D AV A F N GQ ++ V+ I+ Sbjct: 247 HAANS-VKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTAVCSNQFLVQRGIH 305 Query: 334 EEFVRRSVERAKR-RVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL 392 + FV+ E K+ VG+ F+ T QGP I++K K+ + + V++GA + GGK Sbjct: 306 DAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRH 365 Query: 393 GRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452 F EPT+ NVT DM EE FGP+ +++F T +E I AN +D GL ++ Sbjct: 366 QLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQ 425 Query: 453 DINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 D + V+ ++ G V +N + + PFGG K SG GRE ++G+ EY E+K V Sbjct: 426 DPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVC 483 >4YWE-A nrPDB Length = 487 Score = 490 bits (1262), Expect = e-139, Method: Composition-based stats. Identities = 184/482 (38%), Positives = 265/482 (54%), Gaps = 9/482 (1%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 ++ K FI EW PV +P+ G+ + DI++AV AAR + W Sbjct: 9 MEEAKHFIAGEWTLPAQLETIPVVDPSDGQPFATIARGTAPDIERAVAAARD--AFAGPW 66 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 A+ERGR+L +L+ V LA +E+ + GKP QA + + F +YAG A Sbjct: 67 GAASAAERGRVLMRLSARVTDSIEELAAIEARDTGKPLKQARAD-AAALARYFEFYAGAA 125 Query: 155 DKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ 214 DK+HG T+P Y T EP GV G I+PWN+P+ +F + AL GN V+KPAE Sbjct: 126 DKLHGETLPYQAGYTVLTVREPHGVTGHIVPWNYPMQIFGRSVGAALAAGNACVVKPAED 185 Query: 215 TPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 LS L + L EAG P G +NI+ GYG AGAA+A H GID I+FTGS GKL+ + Sbjct: 186 ACLSVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGIDHISFTGSPATGKLVTQM 245 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 A +++ VTLELGGKSP I+FADADLD A+ + N GQ C+AGSR+ +E ++YE Sbjct: 246 AAENHV-PVTLELGGKSPQIVFADADLDAALPVLVSAIVQNGGQTCSAGSRVLIERAVYE 304 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK---G 391 V R VG P + GP I+ KQ ++ + + +G + G+ Sbjct: 305 PLVERLATAFNGLRVG-PSRADLDCGPLINAKQQQRVWDFLSDAQHDGIPMAAHGQVVAD 363 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 GF+ P + +V R+A+EE+FGPV +RF DE + AN + +GLVA ++T Sbjct: 364 APESGFYQAPALLRDVPPSHRLAQEEVFGPVLAAMRFVDEDEAVALANGTPYGLVAGIWT 423 Query: 452 NDINKALTVSSAMQAGTVWINCYNALNA-QSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 D + + ++ ++AG V+IN Y A + PFGG SG+GRE G L ++ +KT+ Sbjct: 424 RDGARQMRLARRLRAGQVFINNYGAGGGVELPFGGVGHSGHGREKGFEALYGFTALKTIA 483 Query: 511 VK 512 ++ Sbjct: 484 IR 485 >3RHD-A nrPDB Length = 486 Score = 490 bits (1261), Expect = e-139, Method: Composition-based stats. Identities = 166/477 (34%), Positives = 261/477 (54%), Gaps = 21/477 (4%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 +FI+ +W N E V NP + E + ++ + + +A+ A V + + Sbjct: 2 MFIDGKWINRED---MDVINPYSLEVIKKIPALSREEAKEAIDTAEK---YKEVMKNLPI 55 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 ++R +L +A ++ + LA + +++ GKP QA V+++ I TF+ A + + Sbjct: 56 TKRYNILMNIAKQIKEKKEELAKILAIDAGKPIKQA-RVEVERSIGTFKLAAFYVKEHRD 114 Query: 160 MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 IP D D FTR EP+G+ G I P+NFPL + A KIAPA+ GN +V P+ + PL Sbjct: 115 EVIPSD-DRLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVC 173 Query: 220 LYMGALIKEA----GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 + + +I+ A P GV N+L G G G I + ++ I+FTGS++VG+LI + A Sbjct: 174 IELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKA 233 Query: 276 GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEE 335 G K++ LELGG +PNI+ DADL+ AV +G F GQ C + I V+ESI ++ Sbjct: 234 G---FKKIALELGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADK 290 Query: 336 FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 F+ V +AK VG+P D T+ GP I + + ++++ + EG KL GGK Sbjct: 291 FIEMFVNKAKVLNVGNPLDEKTDVGPLISVEHAEWVEKVVEKAIDEGGKLLLGGKRDK-- 348 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 PT+ V D + K E F PV I+R +E+I+ AN++++GL +A+FTNDIN Sbjct: 349 -ALFYPTILE-VDRDNILCKTETFAPVIPIIR-TNEEEMIDIANSTEYGLHSAIFTNDIN 405 Query: 456 KALTVSSAMQAGTVWINCYNALNAQ-SPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 K+L + ++ G V IN + PFGG K SG GRE ++ + E S +KT+ + Sbjct: 406 KSLKFAENLEFGGVVINDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIII 462 >5VBF-A nrPDB Length = 478 Score = 489 bits (1260), Expect = e-138, Method: Composition-based stats. Identities = 154/473 (32%), Positives = 231/473 (48%), Gaps = 6/473 (1%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 +++I+ + +++ R PV +P T + E+ A DID AVQAA AF WR Sbjct: 8 RLYIDGRFHDADGRRTQPVVDPGTTRVLGELPHATAHDIDAAVQAAHRAF---VTWRHES 64 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 R LL + A L + +++ GKP +A ++ + ++A + + Sbjct: 65 PLVRSDLLRRAAALARERAETIGRHITMDQGKPLREA-IAEVVSAAEQLEWHAEEGRRTY 123 Query: 159 GMTIP-VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G +P D EPIGVC PWNFP KIA AL G T+V+K E++P Sbjct: 124 GRVVPARSPDVMQTVLREPIGVCAAFSPWNFPFSQAMHKIAAALASGCTLVLKGPEESPS 183 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 + + + L +AG PPG +NI+ G + + KI+FTGS VGK + A Sbjct: 184 AIVALAQLFHDAGLPPGCLNIVWGVPGDVSKQLIEAPQVRKISFTGSVPVGKQLAALAA- 242 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 337 S +KR+T+ELGG +P ++ ADAD++ A F N GQ C + +R FV+ + ++ FV Sbjct: 243 SLMKRMTMELGGHAPVLVCADADVERAAAMLAAYKFRNAGQVCVSPTRFFVQRAAFDRFV 302 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 397 ++ VG D GP ++ ++I + A+GA++ GG L G Sbjct: 303 CAYLDAVGTIRVGYGLDAGVTMGPLAHARRVDEIDAFVADATAKGAQIATGGMRLPGPGH 362 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457 + PTV T D R+ +E FGP+ I+ F +D+ + AN FGL + FT A Sbjct: 363 YFAPTVVLGPTRDTRLMNDEPFGPIVGIVPFDDLDDALAEANRLPFGLASYAFTTSARNA 422 Query: 458 LTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 +S A++AG V IN + A+ PFGG K SG G E G Y K VT Sbjct: 423 HRISRALEAGMVNINHFGMGPAEIPFGGVKDSGFGSEGGMEAFDGYLVTKFVT 475 >5UR2-A nrPDB Length = 984 Score = 489 bits (1259), Expect = e-138, Method: Composition-based stats. Identities = 185/512 (36%), Positives = 274/512 (53%), Gaps = 28/512 (5%) Query: 12 VKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPA-TGEQVCEVQ 70 VKAD ++ +L + P I INN+ +SG++F NP+ + + V ++Q Sbjct: 475 VKADREKMLKALAEAKASLP----VNVNIVINNK--ELQSGKIFDRVNPSQSDQIVGKIQ 528 Query: 71 EADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGK 130 A ++A+QAA+ A+ W+ + +R L+DKLAD++ RDR L + L GK Sbjct: 529 MATTEQAEQAMQAAQTAY---KTWKNVPCEQRAALVDKLADIMTRDRFKLIATQVLEVGK 585 Query: 131 PFLQAFYVDLQGVIKTFRYYAGWADKIHGMT----IPVDGDYFTFTRHEPIGVCGQIIPW 186 P+ +A D+ I RYYA ++ +P + ++ + GV I PW Sbjct: 586 PWAEA-DGDIGEAIDFCRYYARHMRELQKPLRVGGLPGELSHYIYKSR---GVTAVIAPW 641 Query: 187 NFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTA 246 NFPL + A + A GNTVV+KPAEQ+ + A + +I+EAGFP GVIN LPGYG Sbjct: 642 NFPLAILAGMVTAAAVAGNTVVMKPAEQSTVVAWGLMKMIQEAGFPQGVINFLPGYGEEV 701 Query: 247 GAAIASHIGIDKIAFTGSTEVGKLIQEAA-----GRSNLKRVTLELGGKSPNIIFADADL 301 G I +H IAFTGS VG I A G+ ++KR +E+GGK+ II DADL Sbjct: 702 GEYIVNHKYTTTIAFTGSKAVGLHIMNRAAVVQPGQQHVKRCIIEMGGKNAVIIDNDADL 761 Query: 302 DYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGP 361 D AV+ F GQ C+A SR+ V + +Y+ FV R VE AK + +P GP Sbjct: 762 DEAVDGVIYSAFGFSGQKCSAASRVIVLDEVYDRFVDRLVETAKSIEIHPAENPKAYMGP 821 Query: 362 QIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGP 421 +DK+ Y++IL I + KL G G GFF PT+F +V D ++A+ EIFGP Sbjct: 822 VVDKEAYDRILGTIAEA-EKNHKLLFKGSVPGG-GFFAPPTIFGDVPGDAKLAQAEIFGP 879 Query: 422 VQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWIN--CYNALNA 479 V ++R K +D+ ++ AN++++ L VF+ V ++ G +++N A+ Sbjct: 880 VVAVIRAKNLDQALDIANSTEYALTGGVFSRSPANINRVKEELEVGNLYVNRGITGAMVD 939 Query: 480 QSPFGGFKMSGNGRE-MGEFGLREYSEVKTVT 510 + PFGGFKMSG G + G L++Y E VT Sbjct: 940 RHPFGGFKMSGIGSKTGGPDYLKQYMEPACVT 971 >3RH9-A nrPDB Length = 506 Score = 488 bits (1257), Expect = e-138, Method: Composition-based stats. Identities = 160/471 (33%), Positives = 251/471 (53%), Gaps = 7/471 (1%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 +I W++S G F VYNPATG + +V + D+ AV+A + A L + W Sbjct: 15 YIGGRWKDSAGGATFDVYNPATGSVIAKVPSMPEEDVVAAVEAGQSALRLTNPW---PIE 71 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 R + L+ + D ++ +R + + + GKP+ +A ++ F Y A + Sbjct: 72 TRRKWLEDIRDGLKENREEIGRILCMEHGKPWKEAQ-GEVDYAAGFFDYCAKHISALDSH 130 Query: 161 TIPVDGDYFTFTRH-EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 TIP T+T H P+GV G I+PWNFP+ M A K++ AL G VIKPA +TPL+ Sbjct: 131 TIPEKPKDCTWTVHYRPVGVTGLIVPWNFPIGMIAKKLSAALAAGCPSVIKPASETPLTM 190 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 + +++ + P G++N++ G G + H + ++FTGSTEVG+ + Sbjct: 191 IAFFSVMDKLDLPDGMVNLVMGKASVIGKVLCEHKDVPMLSFTGSTEVGRKLIVDTAEQ- 249 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 +K++ LELGG +P I+F DADL+ A + F GQ C +RIFV E + + F ++ Sbjct: 250 VKKLALELGGNAPFIVFDDADLEAAADNLIANKFRGGGQTCVCANRIFVHEKVADAFGQK 309 Query: 340 SVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG-RKGFF 398 ER + VG + + GP I+K+ ++K+ +Q + +GA L G + G F Sbjct: 310 LAERVNKMTVGDGMNDGIDIGPLINKQGFDKVKRHLQDALDKGASLVAGKQPAELGDGLF 369 Query: 399 IEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKAL 458 PTV V +M +EE FGP+ + F+T +EVI+ N+++FGL + VFT D +A Sbjct: 370 FPPTVVQGVDREMCCYQEETFGPLVPMALFRTEEEVIDAGNDTEFGLASYVFTADAERAQ 429 Query: 459 TVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 V++ ++ G V N ++PFGG K SG GRE G GL E+ E +TV Sbjct: 430 RVAAGLRFGHVGWNTGTGPTPEAPFGGMKASGIGREGGLEGLFEFVEAQTV 480 >5TJR-A nrPDB Length = 531 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 151/489 (30%), Positives = 246/489 (50%), Gaps = 16/489 (3%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K I E +++GR V+NP+TGE V +V AD+ + +A+ AA+ AF WR Sbjct: 38 KHLIGGELI-ADTGRTADVFNPSTGEAVRKVPLADRETMQQAIDAAKAAF---PAWRNTP 93 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ++R ++L + L+E + + + S GK A +L+ I+ Y + + Sbjct: 94 PAKRAQVLFRFKQLLEANEERIVKLISEEHGKTIEDAA-GELKRGIENVEYATAAPEILK 152 Query: 159 GM-TIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G + V + ++ +PIGV I P+NFP ++ W A+ CGNT ++KP+E+ P Sbjct: 153 GEYSRNVGPNIDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPS 212 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 S L + L EAG P GV+N++ G A+ + ++F GST + + I G Sbjct: 213 STLLIAELFHEAGLPKGVLNVVHGDKGAV-DALIEAPEVKALSFVGSTPIAEYIYSE-GT 270 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS-RIFVEESIYEEF 336 KRV G K+ ++ DADLD AV + + G+ C A S + V + I + Sbjct: 271 KRGKRVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQIADAL 330 Query: 337 VRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG--- 393 V++ V + K +G+ + GP + +K+ I +GVA+GA+L G+G Sbjct: 331 VQKLVPQIKGLKIGAGTSCGLDMGPLVTGAARDKVTGYIDTGVAQGAELVVDGRGYKVAG 390 Query: 394 -RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTN 452 GFF+ T+F VT +M I KEEIFGPV I+R +++E ++ N+ ++G +FT Sbjct: 391 HENGFFLGGTLFDRVTPEMTIYKEEIFGPVLCIVRVNSLEEAMQLINDHEYGNGTCIFTR 450 Query: 453 DINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMS--GNGREMGEFGLREYSEVKTV 509 D A ++ G V +N + A FGG+K S G+ G G+R Y++ K + Sbjct: 451 DGEAARLFCDEIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTKRKAI 510 Query: 510 TVKIPQKNS 518 T + PQ+ S Sbjct: 511 TQRWPQRKS 519 >4X0T-A nrPDB Length = 513 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 144/480 (30%), Positives = 227/480 (47%), Gaps = 14/480 (2%) Query: 43 NNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASER 102 N W G V Y PA E + V++A AD ++ V+ AR A+ +W + A +R Sbjct: 30 NGSW--GGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAW---KIWADIPAPKR 84 Query: 103 GRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTI 162 G ++ ++ D + VL ++ SL GK ++ ++Q + Y G + I G + Sbjct: 85 GEIVRQIGDALREKIQVLGSLVSLEMGKILVEGV-GEVQEYVDICDYAVGLSRMIGGPIL 143 Query: 163 PVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALY 221 P + + + P+G+ G I +NFP+ ++ W A A+ CGN + K A T L ++ Sbjct: 144 PSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVA 203 Query: 222 MGALIK---EAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 + +I E PG I L G G A+A ++ ++FTGST+VGK + + Sbjct: 204 VTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QE 262 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338 R LELGG + I F DADL V A GQ CT R+F+ ESI++E V Sbjct: 263 RFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVN 322 Query: 339 RSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFF 398 R + + VG+P+DP GP K+ + L ++ EG + GGK + R G + Sbjct: 323 RLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNY 382 Query: 399 IEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKAL 458 +EPT+ + + D IA E F P+ + +FK +EV N GL +++FT D+ + Sbjct: 383 VEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIF 442 Query: 459 TV--SSAMQAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQ 515 G V +N + FGG K +G GRE G ++Y T T+ + Sbjct: 443 RWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSK 502 >4DNG-A nrPDB Length = 485 Score = 477 bits (1227), Expect = e-135, Method: Composition-based stats. Identities = 149/479 (31%), Positives = 245/479 (51%), Gaps = 12/479 (2%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 K FIN +W ESGR + NP + A ++ A A+ A W + Sbjct: 7 NKSFINGKWTGGESGRTEDILNPYDQSVITTASLATGKQLEDAFDIAQKA---QKEWAKS 63 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 +R +L K + +R + M + G +++ ++L+ I + ++ Sbjct: 64 TTEDRKAVLQKARGYLHENRDDIIMMIARETGGTIIKS-TIELEQTIAILDEAMTYTGEL 122 Query: 158 HG-MTIPVDGDYFTFTRHE-PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 G +P D + T + P+GV I P+NFP+ + IAPA+ GN+VV KP QT Sbjct: 123 GGVKEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGNSVVHKPDIQT 182 Query: 216 PLSA-LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274 +S + + AG P GV+N++ G + ++ I+FTGST VG+ I E Sbjct: 183 AISGGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGMLTNPIPRLISFTGSTAVGRHIGEI 242 Query: 275 AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYE 334 AGR+ KR+ LELGG +P + +DAD+D AV+ A G F +QGQ C +RI V + +Y+ Sbjct: 243 AGRA-FKRMALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQDVYD 301 Query: 335 EFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGR 394 EFV + R K+ G DP T GP I+++Q K LE+I+ +G +L GK + Sbjct: 302 EFVEKFTARVKQLPYGDQTDPKTVVGPLINERQIEKALEIIEQAKTDGIELAVEGKRV-- 359 Query: 395 KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDI 454 G + P VF ++ +IA+ E+F P+ I++ + E I+ AN++++GL +AVFT+D+ Sbjct: 360 -GNVLTPYVFVGADNNSKIAQTELFAPIATIIKAGSDQEAIDMANDTEYGLSSAVFTSDL 418 Query: 455 NKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 K + + +G +N + + FGG K SG GR + + E++ K ++++ Sbjct: 419 EKGEKFALQIDSGMTHVNDQSVNDSPNIAFGGNKASGVGRFGNPWVVEEFTVTKWISIQ 477 >4ZZ7-A nrPDB Length = 501 Score = 476 bits (1226), Expect = e-135, Method: Composition-based stats. Identities = 146/485 (30%), Positives = 240/485 (49%), Gaps = 16/485 (3%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 IN + +E+ R V+NPATGE ++ A +++A+ AA+ AF WR Sbjct: 9 HLINGQLV-TENTRSQNVFNPATGEIGKQLDLASTKTVEQAISAAQHAF---PTWRNTPP 64 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 +R R++ + +L+E+ + + GK A +LQ I+ Y G + + G Sbjct: 65 LKRARVMFRFKELLEQHADEICRLIGEEHGKIAHDAM-GELQRGIENVEYACGAPELLKG 123 Query: 160 MT-IPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 V +++ +P+GV I P+NFP+++ W A+ CGN V+KP+E+ P S Sbjct: 124 EHSRNVGPGIDSWSEFQPMGVVAGITPFNFPVMVPLWMFPMAIVCGNCFVLKPSERDPSS 183 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 LY+ L++EAG P GV+N++ G A A+ + ++F GST + + I A + Sbjct: 184 TLYIAQLLQEAGLPDGVMNVVNGD-KEAVDALLHDDRVKAVSFVGSTPIAEYIYRTAS-A 241 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGS-RIFVEESIYEEFV 337 N KR G K+ I+ DAD+D AV Q F + G+ C A S + V ++ + V Sbjct: 242 NGKRCQALGGAKNHAIVMPDADMDNAVNQLLGAAFGSSGERCMALSVAVAVGDAAGDALV 301 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG---- 393 + + ++ VG D + GP I ++ K++ I S +GA + G+ Sbjct: 302 SKMTQAMQKLKVGPSTDSGNDFGPVITRQHQEKVIGYINSAEQQGATIVVDGRQPKVPNH 361 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 GFF+ T+ +VT +M +EEIFGPV +++R TM + ++ + ++G +FT D Sbjct: 362 ENGFFVGGTLIDHVTPEMTSYQEEIFGPVLQVVRVATMQDAMDLIDAHEYGNGTCIFTRD 421 Query: 454 INKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMS--GNGREMGEFGLREYSEVKTVT 510 A S +Q G V IN + A FGG+K S G+ G +R Y++ KTVT Sbjct: 422 GEAARYFSDNIQVGMVGINIPLPVPVAYHSFGGWKRSLFGDLHAYGPDAVRFYTKRKTVT 481 Query: 511 VKIPQ 515 + P Sbjct: 482 QRWPS 486 >3R64-A nrPDB Length = 508 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 166/487 (34%), Positives = 251/487 (51%), Gaps = 11/487 (2%) Query: 35 IKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 I TK I +W S R+ NP + E ++A AD+D A +AA+ A + W Sbjct: 10 IDATKHLIGGQWVEGNSDRISTNINPYDDSVIAESKQASIADVDAAYEAAKKA---QAEW 66 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 154 A+ER ++ + A+L+E R + G +A +++ + A + Sbjct: 67 AATPAAERSAIIYRAAELLEEHREEIVEWLIKESGSTRSKA-NLEITLAGNITKESASFP 125 Query: 155 DKIHGMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 ++HG P + GV G I PWNFPL + +APAL GN VVIKPA Sbjct: 126 GRVHGRISPSNTPGKENRVYRVAKGVVGVISPWNFPLNLSIRSVAPALAVGNAVVIKPAS 185 Query: 214 QTPLSALYM-GALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQ 272 TP++ + + +EAG P GVI+ + G G G +H I+FTGST VG+ + Sbjct: 186 DTPVTGGVIPARIFEEAGVPAGVISTVAGAGSEIGDHFVTHAVPKLISFTGSTPVGRRVG 245 Query: 273 EAA-GRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331 E A +K V LELGG +P ++ ADAD+D A + A G F +QGQ C + +R+ V+ + Sbjct: 246 ELAINGGPMKTVALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVIVDAA 305 Query: 332 IYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKG 391 +++EF+ + VE K G P T GP I+ Q + + E I+ EGA ++ G Sbjct: 306 VHDEFLEKFVEAVKNIPTGDPSAEGTLVGPVINDSQLSGLKEKIELAKKEGATVQVEGPI 365 Query: 392 LGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451 +G + P VFS+VT DM IA+EEIFGP+ +L+ E AN SDFGL AAV++ Sbjct: 366 ---EGRLVHPHVFSDVTSDMEIAREEIFGPLISVLKADDEAHAAELANASDFGLSAAVWS 422 Query: 452 NDINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 DI++A + + +G V IN + FGG K SG GR G++ + E++ + + Sbjct: 423 KDIDRAAQFALQIDSGMVHINDLTVNDEPHVMFGGSKNSGLGRFNGDWAIEEFTTDRWIG 482 Query: 511 VKIPQKN 517 +K +N Sbjct: 483 IKRSAEN 489 >2QE0-A nrPDB Length = 475 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 157/485 (32%), Positives = 240/485 (49%), Gaps = 20/485 (4%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 K K ++N EW+ SE+ +Y PA+G ++ V ++D +A+ A WR Sbjct: 3 KQYKNYVNGEWKLSENE--IKIYEPASGAELGSVPAMSTEEVDYVYASAKKA---QPAWR 57 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 + ER L K+AD++ RD+ + + S K + A ++ + Y A Sbjct: 58 ALSYIERAAYLHKVADILMRDKEKIGAILSKEVAKGYKSAVS-EVVRTAEIINYAAEEGL 116 Query: 156 KIHGMTI------PVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 ++ G + R EP+G+ I P+N+P+ + KIAPAL GN + Sbjct: 117 RMEGEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAF 176 Query: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 KP Q +S L + EAG P GV N + G G G I H ++ I FTGST +G+ Sbjct: 177 KPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGE 236 Query: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329 I + AG ++ + L LGGK I+ DADL+ + G F GQ CTA R+ V Sbjct: 237 RIGKMAG---MRPIMLALGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVLVM 293 Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 ES+ +E V + E+ +G+P D + P ID K + + LI +GA Sbjct: 294 ESVADELVEKIREKVLALTIGNPED-DADITPLIDTKSADYVEGLINDANDKGATALT-- 350 Query: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449 + R+G I P +F VT DMR+A EE FGPV I+R +++E IE +N S++GL A++ Sbjct: 351 -EIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYGLQASI 409 Query: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEVKT 508 FTND +A ++ ++ GTV IN + PF G K SG G + ++ + + VK+ Sbjct: 410 FTNDFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAMTTVKS 469 Query: 509 VTVKI 513 V I Sbjct: 470 VVFDI 474 >4PXN-A nrPDB Length = 525 Score = 470 bits (1210), Expect = e-133, Method: Composition-based stats. Identities = 140/480 (29%), Positives = 220/480 (45%), Gaps = 15/480 (3%) Query: 44 NEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERG 103 W SG +P + + EV EA D ++ ++A F W + A +RG Sbjct: 44 GAW--GGSGPTVTSTSPTNNQVIAEVVEASVHDYEEGMRAC---FDAAKTWMAIPAPKRG 98 Query: 104 RLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIP 163 ++ ++ D + L + SL GK + ++Q +I Y G + +++G IP Sbjct: 99 EIVRQIGDALRAKLHHLGRLVSLEMGKILPEG-IGEVQEIIDMCDYAVGLSRQLNGSIIP 157 Query: 164 VD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYM 222 + ++ P+GV G I +NFP + W AL CGN VV K A TPL + M Sbjct: 158 SERPNHMMMEVWNPLGVVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAM 217 Query: 223 GALIK---EAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 ++ E PG I G G AIA I I ++FTGST G ++Q+ + Sbjct: 218 TKIVASVLEKNNLPGAIFTSFCGGTEIGQAIALDIRIPLVSFTGSTRAGLMVQQQVS-AR 276 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 + LEL G + I+ DAD+ AV GQ CT R+ + E+IY+ F+ + Sbjct: 277 FGKCLLELSGNNAIIVMDDADIQLAVRSVLFAAVGTAGQRCTTCRRLILHENIYQTFLDQ 336 Query: 340 SVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFI 399 VE K+ +G P + T GP L+ IQ+ ++G K+ GG + +G F+ Sbjct: 337 LVEVYKQVRIGDPLEKGTLLGPLHTPASKENFLKGIQTIKSQGGKILFGGSAIESEGNFV 396 Query: 400 EPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALT 459 +PT+ +T + KEE+FGPV +++F+T+ E IE N+ GL +++FT + Sbjct: 397 QPTIVE-ITPSAPVVKEELFGPVLYVMKFQTLKEAIEINNSVPQGLSSSIFTKRPDIIFK 455 Query: 460 V--SSAMQAGTVWINC-YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQK 516 G V +N N FGG K +G GRE G ++Y T T+ + Sbjct: 456 WLGPHGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRATCTINYGSE 515 >3PRL-A nrPDB Length = 505 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 166/486 (34%), Positives = 241/486 (49%), Gaps = 18/486 (3%) Query: 37 YTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRR 96 I N EW S +G + PA+G + + + +++ A+Q A+ A +W+ Sbjct: 11 NANILRNGEWVESRTGERISISAPASGVALGSIPALSQEEVNDAIQGAKDA---QKIWKI 67 Query: 97 MDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADK 156 ER LL ADL+E + ++ + KP A ++ R+ A A + Sbjct: 68 RPIHERVDLLYAWADLLEERKEIIGELIMHEVAKPKKSA-IGEVSRTADIIRHTADEALR 126 Query: 157 IHGMTIPVDG------DYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 ++G T+ D EP+GV I P+N+P+ + A KIAPAL GNTVV K Sbjct: 127 LNGETLKGDQFKGGSSKKIALVEREPLGVVLAISPFNYPVNLAAAKIAPALVTGNTVVFK 186 Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKL 270 PA Q LS + M + +AG P G+I ++ G G G + H GID I FTG T G+ Sbjct: 187 PATQGSLSGIKMVEALADAGAPEGIIQVVTGRGSVIGDHLVEHPGIDMITFTGGTTTGER 246 Query: 271 IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 I E A + V LELGGK P I+ DADL Q G F GQ CTA R+FV++ Sbjct: 247 ISEKA---KMIPVVLELGGKDPAIVLDDADLKLTASQIVSGAFSYSGQRCTAIKRVFVQD 303 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 S+ ++ V E ++ VGSP D + P ID+K I LI + GA L G K Sbjct: 304 SVADQLVANIKELVEQLTVGSPED-DADITPVIDEKSAAFIQGLIDDALENGATLLSGNK 362 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 R+G + PT+ +VT MR+A EE FGPV I+R K +E I +N SD+GL A++F Sbjct: 363 ---RQGNLLSPTLLDDVTPAMRVAWEEPFGPVLPIIRVKDANEAISLSNQSDYGLQASIF 419 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNGREMGEFGLREYSEVKTV 509 T D ++A+ + ++ GTV IN PF G K SG G + + L + + Sbjct: 420 TKDTDRAINIGKHLEVGTVHINAKTERGPDHFPFLGVKKSGLGVQGIKPSLLSMTRERVT 479 Query: 510 TVKIPQ 515 + + + Sbjct: 480 VLNLAE 485 >3VZ3-A nrPDB Length = 457 Score = 463 bits (1191), Expect = e-130, Method: Composition-based stats. Identities = 146/458 (31%), Positives = 217/458 (47%), Gaps = 6/458 (1%) Query: 55 FPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVE 114 NP TGE + A+ID + A+ AF RR S+R + L+ A ++E Sbjct: 6 IATINPTTGEICQRFKALTPAEIDAKLAKAQEAFQAY---RRTSFSQRRQWLENAAAILE 62 Query: 115 RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRH 174 RD + A + + GK Q+ + + RYYA ++ ++ + Sbjct: 63 RDTSKFAEIMTTEMGKT-HQSAIAEAEKSALVCRYYAEHGEQFLANEYTETQATESYVCY 121 Query: 175 EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPG 234 +P+G+ ++PWNFP APAL GN V+K A P AL + A+++ AGFP G Sbjct: 122 QPLGILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAAGFPEG 181 Query: 235 VINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNI 294 V L G + + + TGS G + AG+ +K LELGG P + Sbjct: 182 VFQTLL-IGASQVEQVIKDPRVKAATLTGSEPAGASLASLAGQ-EIKPTLLELGGSDPFV 239 Query: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFD 354 +F ADLD AVE N GQ A R + E+I EF+ + + +G P Sbjct: 240 VFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKIGDPMA 299 Query: 355 PTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIA 414 P T+ GP + I + VA GAK+ GG+ L R G+F PT+ + + +I Sbjct: 300 PETDIGPLATEGILQDISRQVDQAVAAGAKILLGGRPLDRAGYFYPPTILTEIPPGAKIL 359 Query: 415 KEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCY 474 +EE+F PV + K +D+ I AN+ FGL A+ +TND + + AG V+IN Sbjct: 360 QEELFAPVAMVFTVKDLDQAIALANDIPFGLGASAWTNDPAEQQRFIQELDAGAVFINGM 419 Query: 475 NALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + + PFGG K SG GRE+G G+R + KTV +K Sbjct: 420 VKSDPRLPFGGTKRSGYGRELGLAGIRTFVNAKTVWLK 457 >6MVR-A nrPDB Length = 767 Score = 462 bits (1190), Expect = e-130, Method: Composition-based stats. Identities = 186/471 (39%), Positives = 272/471 (57%), Gaps = 24/471 (5%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 FI W G +F NPATG+ + +V +A +AD+D AV+AAR A W + D Sbjct: 35 HFIGGAWTAP--GDLFATVNPATGQTLAQVSQATQADVDAAVKAARKA---QPAWAK-DG 88 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 + R R+L LA L+++ + A +E+L+ GKP +A +D+ + F ++AG+A ++ G Sbjct: 89 AARARVLYALARLLQKHARLFAVLETLDNGKPIREARDIDVPLAQRHFYHHAGYA-QLMG 147 Query: 160 MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 +P P+GVCGQ+IPWNFPLLM AWKIAPAL GNTVV+KPAE TPL+A Sbjct: 148 TEMPD---------RAPLGVCGQVIPWNFPLLMLAWKIAPALAMGNTVVLKPAEWTPLTA 198 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 L + +AG P GV+NI+ G G G I + +DK+AFTGST VG+ I+EA + Sbjct: 199 LLFADICGQAGVPAGVVNIVTGDGA-VGEMIVT-AQVDKVAFTGSTAVGRRIREATAGT- 255 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 K ++LELGGK P ++ DAD+D AVE ++FNQGQ C AGSR+ V+E I + F + Sbjct: 256 GKALSLELGGKGPYVVCDDADIDSAVEGLVDAIWFNQGQVCCAGSRLLVQEGIADVFHAK 315 Query: 340 SVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFI 399 R +G P D + G + Q ++ +++ +G + G + Sbjct: 316 LRARMDSLRIGDPLDKCIDIGAMVHPDQLARVRDMVA-ANTDGEVYQT----AVPAGCYY 370 Query: 400 EPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALT 459 PT+ S + + ++EIFGPV F+T E +E ANN+ +GL A+V++ ++N AL Sbjct: 371 PPTLISGLAPASPLMQQEIFGPVLVSTTFRTPAEAVEIANNTAYGLAASVWSENVNLALD 430 Query: 460 VSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 ++ + AG VWIN N ++A +PFGG + SG GRE G GL Y+ T Sbjct: 431 LAPKLVAGIVWINGTNMMDAAAPFGGVRESGFGREGGWEGLAGYTRPAIAT 481 Score = 124 bits (311), Expect = 1e-28, Method: Composition-based stats. Identities = 63/247 (25%), Positives = 98/247 (39%), Gaps = 12/247 (4%) Query: 36 KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWR 95 + K++I + + G VY P G+ + +++ D+ AV+A A S W Sbjct: 501 RTAKLYIGGKQTRPDGGYSRAVYGPK-GKLLGHASLSNRKDLRNAVEAMNAA----SGWS 555 Query: 96 RMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWAD 155 R R ++L + + + A GK ++ I A WAD Sbjct: 556 RTTGHLRAQILYFIGENLSARADEFANRIKDMTGK----DGKAEVAASIDRLFSAAAWAD 611 Query: 156 KIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 K G V EP+G G + P PLL +APA+ GN V + +E Sbjct: 612 KYDGQVKGVPLRGVALAMKEPVGKIGILCPDAAPLLGLVSLMAPAIAMGNRVTLAASEAF 671 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 PL+A ++ + P GV+NIL G +A H+ +D + + EAA Sbjct: 672 PLAATDFYQVLDTSDVPAGVVNILTGAHADLAEPMARHLDLDAVW---GLSGHAQVIEAA 728 Query: 276 GRSNLKR 282 NLKR Sbjct: 729 SAGNLKR 735 >6FK3-A nrPDB Length = 536 Score = 462 bits (1190), Expect = e-130, Method: Composition-based stats. Identities = 181/498 (36%), Positives = 259/498 (52%), Gaps = 29/498 (5%) Query: 40 IFINNEWQNSESGRVFPVYNPATGE-QVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 + E G + NP+ E V EADK + KA AR AF+ W R Sbjct: 22 HLVGGE--EVLEGPLLERRNPSDREDVVARFPEADKDLVRKAALKAREAFA---EWSRTP 76 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 A RG++L L ++ER++ L + GK +A D+Q I T ++A +++ Sbjct: 77 APIRGQVLFNLVKILEREKPTLTRLMVREVGKTPKEAA-GDVQEAIDTALFFASEGRRLY 135 Query: 159 GMTIPVD-GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G T+P + D FT P+GV G I NFP+ + +WK+ PA+ GNTVV KP+E P Sbjct: 136 GQTVPSEMRDKELFTFRRPLGVVGIITAGNFPIAVPSWKLIPAVLTGNTVVWKPSEDAPT 195 Query: 218 SALYMGALIKEAGFPPGVINILPGYGP-TAGAAIASHIG---IDKIAFTGSTEVGKLIQE 273 + L +EAG PPGV+N++ G G + G + + K AFTGST+VG+ I E Sbjct: 196 LSFVFAKLFEEAGLPPGVLNVVFGGGKGSTGQWMVELMDEGLFQKFAFTGSTQVGRWIGE 255 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 AGR NL R TLELGGK+P ++ DADLD AVE A F GQ CT+ I V+ IY Sbjct: 256 VAGR-NLIRPTLELGGKNPLVVMRDADLDLAVEGAWWSAFATGGQRCTSAGNILVDAPIY 314 Query: 334 EEFVRRSVERAKRRVVGSP-FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL 392 EEF RR +ER + +VG+P P GP I+++ + + E + G AEGA+L G + Sbjct: 315 EEFKRRFLERVEATLVGNPLLHPEVTYGPFINERFFARWQEHYRVGEAEGARLLFGRGRI 374 Query: 393 GRK------------GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANN 440 R+ G + PTV+ V R+ EE+FGP +++ ++E I AN+ Sbjct: 375 TRENPYPRFLGDPEAGLYGWPTVWE-VRPGTRLFTEEVFGPTINLVKVDGIEEAIAVANS 433 Query: 441 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINC-YNALNAQSPFGGFKMSGN-GREMGEF 498 + +GL +A++TN + A ++AG IN A PFGG K SGN GRE G + Sbjct: 434 TPYGLSSAIYTNHRHWAYLFKVGIRAGMTSINNATVGAEAHLPFGGVKASGNGGRESGIW 493 Query: 499 GLREYSEVKTVTVKIPQK 516 L EY+ V + + Sbjct: 494 VLEEYTYWHAVNEEYSGR 511 >3EFV-A nrPDB Length = 462 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 141/454 (31%), Positives = 216/454 (47%), Gaps = 6/454 (1%) Query: 57 VYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERD 116 NPATG+ + + A+ +I+ A+ A F W+ ++R + L + + Sbjct: 11 SVNPATGQTLAAMPWANAQEIEHALSLAASGF---KKWKMTSVAQRAQTLRDIGQALRAH 67 Query: 117 RAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEP 176 +A + GKP QA ++ +YA + + + + P Sbjct: 68 AEEMAQCITREMGKPIKQA-RAEVTKSAALCDWYAEHGPAMLNPEPTLVENQQAVIEYRP 126 Query: 177 IGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVI 236 +GV I+PWNFPL P L GN+ ++K A A + ++ EAG P GV Sbjct: 127 LGVILAIMPWNFPLWQVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEAGTPAGVY 186 Query: 237 NILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIF 296 + + + I + TGS A + LK+ LELGG P I+ Sbjct: 187 GWVNANNEGVSQ-MINDPRIAAVTVTGSVRA-GAAIGAQAGAALKKCVLELGGSDPFIVL 244 Query: 297 ADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPT 356 DADL+ AV+ A G + N GQ C A R VEE I + F R V A +G P Sbjct: 245 NDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAFTDRFVAAAAALKMGDPLVEE 304 Query: 357 TEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKE 416 + GP +++ + +Q+ VAEGA+L GG+ + +G + TV ++VT DM ++ Sbjct: 305 NDLGPMARFDLRDELHQQVQASVAEGARLLLGGEKIAGEGNYYAATVLADVTPDMTAFRQ 364 Query: 417 EIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNA 476 E+FGPV I K + AN+S+FGL A +FT D A +++ ++ G V+IN Y+A Sbjct: 365 ELFGPVAAITVAKDAAHALALANDSEFGLSATIFTADDTLAAEMAARLECGGVFINGYSA 424 Query: 477 LNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 +A+ FGG K SG GRE+ FGL E+ V+TV Sbjct: 425 SDARVAFGGVKKSGFGRELSHFGLHEFCNVQTVW 458 >3VZ0-A nrPDB Length = 459 Score = 452 bits (1164), Expect = e-127, Method: Composition-based stats. Identities = 145/458 (31%), Positives = 210/458 (45%), Gaps = 5/458 (1%) Query: 54 VFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLV 113 V+ NP T A + A + W+ ++R ++ + ADL+ Sbjct: 6 VYQTLNPTTETVERSFDLHTPAQMKDITDRAEHVWKT--DWKLRSIAQRKEIVSRAADLL 63 Query: 114 ERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTR 173 RDR A++ + GK A ++ +YA A++ T Sbjct: 64 RRDRQHHASLIATEMGKALPDAL-EEIDVTADILSFYANGAEEFLAPTPLKVKTGQAKII 122 Query: 174 HEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPP 233 ++P+G+ I PWNFP A P L GN V+ K A P AL L +AG P Sbjct: 123 NQPLGIIYCIEPWNFPYYQLARVAGPNLMAGNVVIAKHAPNVPQCALAFEKLFHDAGAPV 182 Query: 234 GVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPN 293 G + A + I +A TGS A + LK+ T+ELGG Sbjct: 183 GAYANIF-LDNDQSAELIKDERIRGVALTGSERA-GQAVAAQAGAALKKDTMELGGSDAF 240 Query: 294 IIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPF 353 I+ DADLD AV+ A G F N GQ CTA R+ V E +Y+ F+ R +G+P Sbjct: 241 IVLDDADLDLAVKWAVWGRFANNGQVCTAAKRMIVHEKVYDAFLDGLKTAITRFRIGNPL 300 Query: 354 DPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRI 413 D T GP + L+ V GA L GGK + RKGFF+EPT+ ++V+ D + Sbjct: 301 DRDTTHGPMSSLRAMELALDQTAEAVKGGATLVAGGKRMDRKGFFMEPTILTDVSKDNPV 360 Query: 414 AKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINC 473 +EIFGPV + + + I+ AN+S +GL AVF+ DI +A V+ ++ G V+IN Sbjct: 361 FYQEIFGPVAVVHKVASEQAAIDLANDSPYGLGGAVFSRDIARAEKVAEQVETGMVFINT 420 Query: 474 YNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511 A + PFGG K SG GRE+ G+ E+ K V + Sbjct: 421 ATAAAPELPFGGIKNSGFGRELSFLGIEEFINRKLVRI 458 >4OGD-A nrPDB Length = 465 Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats. Identities = 141/461 (30%), Positives = 212/461 (45%), Gaps = 11/461 (2%) Query: 60 PATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD-ASERGRLLDKLADLVERDRA 118 P T E + + ++ A L WR+ D ER L ++A+++ RDR Sbjct: 8 PYTNEVLHTFDNMTDQGLADVLE---RAHLLYKKWRKEDHLEERKAQLHQVANILRRDRD 64 Query: 119 VLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIG 178 A + + + GK F +A ++ YYA AD+ T + + G Sbjct: 65 KYAEIMTKDMGKLFTEAQ-GEVDLCADIADYYADKADEFLMSTPLETDSGQAYYLKQSTG 123 Query: 179 VCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVI-N 237 V + PWNFP AP GN +V+K A P SA L+ EAG G I N Sbjct: 124 VILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEAGAEAGSITN 183 Query: 238 ILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFA 297 + Y + + + + + TGS G I E AG+ NLK+ TLELGG II Sbjct: 184 LFISYDQV--SQVIADKRVVGVCLTGSERGGASIAEEAGK-NLKKTTLELGGDDAFIILD 240 Query: 298 DADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTT 357 DAD D + + +N GQ CT+ R V + Y+ F + K G P DP T Sbjct: 241 DADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGDPMDPET 300 Query: 358 EQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEE 417 P + +L+ I+ + GA+L GG+ + G F+ PT+ + +T D I +E Sbjct: 301 TLAPLSSAQAKADVLDQIKLALDHGAELVYGGEAIDHPGHFVMPTIIAGLTKDNPIYYQE 360 Query: 418 IFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNAL 477 IFGPV EI + + +E IE AN+S++GL +F+++ A V++ ++ G +IN Sbjct: 361 IFGPVGEIYKVSSEEEAIEVANDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFINSGWTS 420 Query: 478 NAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 518 + PFGG K SG GRE+ E G + + IP K + Sbjct: 421 LPELPFGGIKHSGYGRELSELGFTSFVN--EHLIYIPNKTN 459 >3ROS-A nrPDB Length = 484 Score = 448 bits (1153), Expect = e-126, Method: Composition-based stats. Identities = 134/450 (29%), Positives = 207/450 (46%), Gaps = 8/450 (1%) Query: 57 VYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERD 116 NP T E ID+A+ A L WR + + R +L +A+ ++ Sbjct: 8 SVNPYTNEAFASYDNPTSKQIDEAINLAHA---LYKKWRHEEPASRAEILHDIANALKEH 64 Query: 117 RAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEP 176 LA M +L GK ++ +++ + YYA ++ T + + Sbjct: 65 EDELAKMMTLEMGKLLSES-KEEVELCVSICNYYADHGPEMLKPTKLNSDLGNAYYLKQS 123 Query: 177 IGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPG-V 235 GV PWNFPL AP GN +++K A P SA +IK AG P G + Sbjct: 124 TGVIMACEPWNFPLYQVIRVFAPNFIVGNPILLKHAHNVPGSAALTAKIIKRAGAPEGSL 183 Query: 236 INILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNII 295 IN+ P Y A I + I +A TGS G + EAAG+ NLK+ T+ELGG I+ Sbjct: 184 INLYPSYDQLAD--IIADPRIQGVALTGSERGGSAVAEAAGK-NLKKSTMELGGNDAFIV 240 Query: 296 FADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDP 355 DAD + +N GQ CT+ RI VE+S Y+E + G P + Sbjct: 241 LDDADPQVLRNVLNDARTYNDGQVCTSSKRIIVEKSRYDEVLHELKNVFSNLKAGDPLEA 300 Query: 356 TTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAK 415 T P +K K+ ++ + GAK+ + KG F PT+ +++ D + Sbjct: 301 DTTLPPMNSEKAKEKLEAQVKEAIDAGAKVFYQYPEIDSKGAFFRPTILTDIAKDNPVFD 360 Query: 416 EEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYN 475 +E+FGP+ E+ + + I+ AN+S +GL ++V +DI++A VS+ ++ G IN Sbjct: 361 KEVFGPIAEVFVVEDDNAAIQLANDSSYGLGSSVIGSDIDRAKKVSAQIETGMTVINGRW 420 Query: 476 ALNAQSPFGGFKMSGNGREMGEFGLREYSE 505 + + PFGG K SG GRE+ GL + Sbjct: 421 ITSGELPFGGIKKSGYGRELSGLGLMAFVN 450 >2J5N-A nrPDB Length = 516 Score = 445 bits (1146), Expect = e-125, Method: Composition-based stats. Identities = 173/482 (35%), Positives = 242/482 (50%), Gaps = 21/482 (4%) Query: 40 IFINNEWQNSESGRVFPVYNP-ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 ++I EW + + NP A E V +A KA+ + A++AA AF W+ Sbjct: 40 LYIGGEWVD--TKERMVSLNPSAPSEVVGTTAKAGKAEAEAALEAAWKAF---KTWKDWP 94 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +R RLL K A L+ R + L GK +++A D+ I YYA A + Sbjct: 95 QEDRSRLLLKAAALMRRRKRELEATLVYEVGKNWVEAS-ADVAEAIDFIEYYARAALRYR 153 Query: 159 ---GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 +P G+ + + P+G I PWNFP+ +F I + GNTV+ KPAE Sbjct: 154 YPAVEVVPYPGEDNE-SFYVPLGAGVVIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDA 212 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 + + + EAGFPPGV+N LPG G GA + H I I FTGS EVG I EAA Sbjct: 213 VVVGAKVFEIFHEAGFPPGVVNFLPGVGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAA 272 Query: 276 GR-----SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE 330 GR + KR +E GGK I+ AD D A E + QGQ C+A SR+ + + Sbjct: 273 GRLAPGQTWFKRAYVETGGKDAIIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQ 332 Query: 331 SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK 390 YE + R ++RA+R VG P + + GP + +Q K+L I+ G EG +L GGK Sbjct: 333 GAYEPVLERVLKRAERLSVG-PAEENPDLGPVVSAEQERKVLSYIEIGKNEG-QLVLGGK 390 Query: 391 GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 L +G+FI PTVF+ V RIA+EEIFGPV ++R K E +E AN++ +GL V+ Sbjct: 391 RLEGEGYFIAPTVFTEVPPKARIAQEEIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVY 450 Query: 451 TNDINKALTVSSAMQAGTVWIN--CYNALNAQSPFGGFKMSGNGREMGE-FGLREYSEVK 507 + G ++ N AL PFGGFK+SG + G LR + E+K Sbjct: 451 SRKREHLEWARREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMK 510 Query: 508 TV 509 V Sbjct: 511 AV 512 >5N5S-A nrPDB Length = 515 Score = 444 bits (1143), Expect = e-125, Method: Composition-based stats. Identities = 157/497 (31%), Positives = 245/497 (49%), Gaps = 20/497 (4%) Query: 24 HLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQA 83 + ++ K IF+ ++ + + V N T + +V +A DID A+ A Sbjct: 26 QKAKESSGDVTPKKYNIFLASKPVDG-DRKWLDVTNKYTNDVAAKVPQATHKDIDDAIDA 84 Query: 84 ARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGV 143 A A + M A ER +L+K+ ++ +A ++ GKP A ++ Sbjct: 85 AVAAAPAMAA---MGAYERKAVLEKVVAELKNRFEEIAQTLTMESGKPIKDA-RGEVTRT 140 Query: 144 IKTFRYYAGWADKIHGMTIPVD-----GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIA 198 I TF+ A + +I+G IP+D + PIG + PWNFPL + A K+A Sbjct: 141 IDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVA 200 Query: 199 PALCCGNTVVIKPAEQTPLSALYMGALIKEAG-FPPGVINILPGYGPTAGAAIASHIGID 257 PA+ G V+KPA +TPLSAL +G ++ + P G +ILP Sbjct: 201 PAIAVGCPFVLKPASRTPLSALILGEILHKIEELPLGAFSILP-VSREDADMFTVDERFK 259 Query: 258 KIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQ 316 + FTGS +G ++ AG+ K+V +ELGG +P I+ DLDY +++ G F+ Sbjct: 260 LLTFTGSGPIGWDMKARAGK---KKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQG 316 Query: 317 GQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQ 376 GQ C R++V E +Y+E V K+ +G+PF+ T GP I + I + ++ Sbjct: 317 GQSCIHMQRLYVHERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVK 376 Query: 377 SGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIE 436 VA+G KL GG RKG FIEPTV +V + KEEIFGPV + ++ E ++ Sbjct: 377 EAVAKGGKLLTGG---NRKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVK 433 Query: 437 RANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ-SPFGGFKMSGNGREM 495 NN+ +GL + +FT D+NKA M+ G V +N AL P+GG K SG RE Sbjct: 434 ECNNTHYGLQSGIFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREG 493 Query: 496 GEFGLREYSEVKTVTVK 512 ++ + + E K + ++ Sbjct: 494 VKYAMDDMLETKVLVMR 510 >4E4G-A nrPDB Length = 521 Score = 443 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 141/485 (29%), Positives = 222/485 (45%), Gaps = 15/485 (3%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 FI+ + SGRV ++NPATGE V A A A A + W + Sbjct: 29 HFIDGKRVAGTSGRVSNIFNPATGEVQGTVALASDA---DLAAAVESAKAAQPKWAATNP 85 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA-DKIH 158 R R+ K L+ + LA M S GK A D+ ++ + G + Sbjct: 86 QRRARVFMKFVQLLNDNMNELAEMLSREHGKTIDDA-KGDIVRGLEVCEFVIGIPHLQKS 144 Query: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 T ++ +P+G+ I P+NFP ++ W APA+ CGN ++KP+E+ P Sbjct: 145 EFTEGAGPGIDMYSIRQPVGIGAGITPFNFPGMIPMWMFAPAIACGNAFILKPSERDPSV 204 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 + + L+ EAG P G++N++ G AI +H I ++F GST + + + A Sbjct: 205 PIRLAELMIEAGLPAGILNVVNGDKGAV-DAILTHPDIAAVSFVGSTPIARYVYGTAA-M 262 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIF-VEESIYEEFV 337 N KR G K+ II DADLD A + + G+ C A S V E + Sbjct: 263 NGKRAQCFGGAKNHMIIMPDADLDQAANALIGAGYGSAGERCMAISVAVPVGEETANRLI 322 Query: 338 RRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 397 + V + +G D + GP + K+ +I LI SG+ +GAKL G+ +G+ Sbjct: 323 DKLVPMVESLRIGPYTDEKADMGPVVTKEAEQRIRSLIDSGIEQGAKLVVDGRDFKLQGY 382 Query: 398 ----FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 FI +F +VT DM I K EIFGPV ++R + +E + ++G A++T D Sbjct: 383 ENGHFIGGCLFDDVTPDMDIYKTEIFGPVLSVVRARNYEEALSLPMKHEYGNGVAIYTRD 442 Query: 454 INKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGR--EMGEFGLREYSEVKTVT 510 + A +S + G V +N + A FGG+K S G + G ++ ++ KT+T Sbjct: 443 GDAARDFASRINIGMVGVNVPIPVPLAYHSFGGWKSSSFGDLNQHGTDSIKFWTRTKTIT 502 Query: 511 VKIPQ 515 + P Sbjct: 503 SRWPS 507 >5U0M-A nrPDB Length = 497 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 149/466 (31%), Positives = 220/466 (47%), Gaps = 11/466 (2%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 ++I+ W G F P TGE V + A D+D AV+ AR AF WRR Sbjct: 13 NVYIDGLWLPGH-GAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFL---AWRRKS 68 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +ER +++ +L+E ++ LA L GKP ++ ++ ++ ++ Sbjct: 69 LAERQAVIEAFGELLEANKEELAHQIGLETGKPLWESRT-EVAAMMGKIPISVKAYNERT 127 Query: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218 G T RH P GV P+NFP + I PAL GNTVV KP+E TP Sbjct: 128 GHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGV 187 Query: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278 A L ++AG P GVIN++ G G G +A H ID + FTGS+ VG L+ E G Sbjct: 188 AELTVRLWEKAGLPDGVINLVQG-GSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGGQ 246 Query: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY-EEFV 337 K + LE+GG +P I+ +DLD AV A Q F + GQ CT R+ V + +EF+ Sbjct: 247 PEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFL 306 Query: 338 RRSVERAKRRVVGS-PFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKG 396 R VE A R V DP G I + N++L+ + + +GA K L Sbjct: 307 ARLVEVAARITVAEFDADPQPFMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPDT 366 Query: 397 FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINK 456 + P + + + +E FGP+ + R+K DE +E ANN+ +GL A + ++D Sbjct: 367 GLLSPGIVD--ATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAGILSDDRKL 424 Query: 457 ALTVSSAMQAGTVWIN-CYNALNAQSPFGGFKMSGNGREMGEFGLR 501 + ++AG V N ++ +PFGG SGN R + Sbjct: 425 YNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYAAD 470 >5KF0-A nrPDB Length = 485 Score = 435 bits (1118), Expect = e-122, Method: Composition-based stats. Identities = 151/480 (31%), Positives = 235/480 (48%), Gaps = 21/480 (4%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 ++ NE + + V + +G+ V AD ID A+ AA A R + A Sbjct: 17 YLANEAVYANTD--LEVTDKFSGKVATRVALADAQAIDAAIGAAVDA---VKPMRELPAY 71 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM 160 R +LD LA + GKP + ++ +I TFR + A +I G Sbjct: 72 RRQAVLDHCVARFRERFDELAEALCIEAGKPINDS-RGEVTRLIDTFRVASEEAVRIDGE 130 Query: 161 TIPVD-----GDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 + ++ Y +TR PIG C I P+NFPL + A K+APAL G V+KPA +T Sbjct: 131 VLNLEISARAQGYTGYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRT 190 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 P+ AL + ++ E P G ++LP + A + ++FTGS VG ++E A Sbjct: 191 PVGALIIAEVLAETNLPKGAFSVLPAHRDGA-DLFTTDERFRLLSFTGSPAVGWALKEKA 249 Query: 276 GRSNLKRVTLELGGKSPNIIFADA--DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 G+ K+V LELGG + I+ AD LDY V++ G ++ GQ C RI V S+Y Sbjct: 250 GK---KKVVLELGGNAAAIVDADQFEQLDYVVDRLAFGAYYQSGQSCIGVQRILVHASLY 306 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 + + V + + +G P DP+T GP I + + ++ + + VA GAK+ GGK Sbjct: 307 DTLRDKLVAKTRSLKMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGAKIIAGGKV-- 364 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 G E T+ +V + + ++E FGPV + +F D+ + R N+SDFGL A VFT+ Sbjct: 365 -DGAMFEATLLEDVGREQDLYRKEAFGPVAILEKFDRFDDALARVNDSDFGLQAGVFTDS 423 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQ-SPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 + A ++ G V IN + P+GG K SG GRE + + + +E + + V+ Sbjct: 424 LTHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTEPRLMVVR 483 >5JRY-A nrPDB Length = 485 Score = 430 bits (1105), Expect = e-121, Method: Composition-based stats. Identities = 150/466 (32%), Positives = 228/466 (48%), Gaps = 19/466 (4%) Query: 55 FPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVE 114 V + +G+ V AD ID A+ AA A R + A +R +LD Sbjct: 29 LEVTDKYSGKVATRVALADAKAIDAAIGAAVDA---TKPMRELPAYKRQAVLDHCVARFR 85 Query: 115 RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVD-----GDYF 169 LA + GKP A ++ +I TFR + A +I G + ++ Y Sbjct: 86 ERFDELAEALCIEAGKPINDA-KGEVTRLIDTFRVASEEAVRIDGEVLNLEISARAQGYT 144 Query: 170 TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA 229 +TR PIG C I P+NFPL + A K+APAL G V+KPA +TP+ AL +G ++ E Sbjct: 145 GYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRTPVGALIIGEVLAET 204 Query: 230 GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGG 289 P G ++LP + A + ++FTGS VG ++E AG+ K+V LELGG Sbjct: 205 DLPKGAFSVLPAHRDGA-DLFTTDDRFRLLSFTGSPAVGWALKEKAGK---KKVVLELGG 260 Query: 290 KSPNIIFADA--DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRR 347 + I+ AD LDY V++ G F+ GQ C RI IY+ + + + + Sbjct: 261 NAAAIVDADQLDRLDYVVDRLAFGAFYQSGQSCIGVQRILAHADIYDALRDKLIAKTRSL 320 Query: 348 VVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNV 407 +G P DP+T GP I + + ++ + + VA GAK+ GGK G E T+ NV Sbjct: 321 KMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGAKIVAGGKV---DGAMFEATLLENV 377 Query: 408 TDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAG 467 D + ++E FGP+ + +F D+ + R N+SDFGL A VFT+ + ++ G Sbjct: 378 GRDQDLYRKEAFGPIAILEKFDRFDDALARVNDSDFGLQAGVFTDSLAHTQQAWDELEVG 437 Query: 468 TVWINCYNALNAQ-SPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 V IN + P+GG K SG GRE + + + +E + + V+ Sbjct: 438 GVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTEPRLLVVR 483 >5J6B-A nrPDB Length = 485 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 150/480 (31%), Positives = 230/480 (47%), Gaps = 21/480 (4%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDAS 100 ++ NE + V + TG+ V AD + ID A+ AA A R + A Sbjct: 17 YLANEAVYAN--AELEVTDKYTGKVATRVALADASAIDAAIAAAVGA---QKPLRALPAF 71 Query: 101 ERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG- 159 R +L+ LA + GKP + ++ +I TFR A + +I G Sbjct: 72 RRQAILEHCVARFRERFDELAQALCIEAGKPINDS-KGEVTRLIDTFRVAAEESVRIEGG 130 Query: 160 ----MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215 P Y + + PIG C I P+NFPL + A K+APAL G V+KPA +T Sbjct: 131 LVNLEISPRAQGYSGYYKRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRT 190 Query: 216 PLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAA 275 P+ AL +G ++ E P G +ILP + A + ++FTGS VG +++ A Sbjct: 191 PIGALIIGEVLAETDLPKGAFSILPAHRDGA-DLFTTDERFKLLSFTGSPTVGWELKKKA 249 Query: 276 GRSNLKRVTLELGGKSPNIIFADAD--LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 G+ V LELGG + I+ AD LDY VE+ G ++ GQ C RI +Y Sbjct: 250 GKKK---VVLELGGNAAAIVDADQREVLDYVVERLAFGAYYQSGQSCIGVQRIIAHADVY 306 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 + + + + + +G P DP T GP I + + ++ +++ VA GAK+ GGK Sbjct: 307 DALREKLIAKTRSLKMGDPKDPATFVGPMISESEARRLAGWMEAAVAAGAKIVAGGKV-- 364 Query: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453 G E T+ V D + ++E FGPV + RF D+ + R N+SDFGL A VFT+ Sbjct: 365 -DGAMFEATLLEGVGRDQDLYRKEAFGPVALLERFSDFDDALARVNDSDFGLQAGVFTDS 423 Query: 454 INKALTVSSAMQAGTVWINCYNALNAQ-SPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 ++ A ++ G V IN + P+GG K SG GRE + + + +E++ + V+ Sbjct: 424 LSHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTELRLMVVR 483 >1UXV-A nrPDB Length = 501 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 153/487 (31%), Positives = 235/487 (48%), Gaps = 24/487 (4%) Query: 41 FINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW--RRMD 98 ++ EW SG+ V +P + +V + ++++ + + F G W R M Sbjct: 22 YLAGEW--GGSGQEIEVKSPIDLATIAKVISPSREEVERTLD---VLFKRGR-WSARDMP 75 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 +ER +L K AD++ER+ V A + +N GKP A +++ + R KI Sbjct: 76 GTERLAVLRKAADIIERNLDVFAEVLVMNAGKP-KSAAVGEVKAAVDRLRLAELDLKKIG 134 Query: 159 GMTIPVDGDYFTF-----TRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 G IP D Y T R EP+GV I P+N+PL KI + GN VV+KP+ Sbjct: 135 GDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSI 194 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 PL A + +AGFPP I +L G A I + + ++FTGSTEVG+ + + Sbjct: 195 SDPLPAAMAVKALLDAGFPPDAIALLNLPGKEAEK-IVADDRVAAVSFTGSTEVGERVVK 253 Query: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333 G +K+ +ELGG P I+ DADLD A ++ +G++ GQ C A + E +Y Sbjct: 254 VGG---VKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVY 310 Query: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393 + V +R VG P DPT + GP I ++++ I+ V +G ++ GG+ LG Sbjct: 311 GKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLG 370 Query: 394 RKGFFIEPTVFSNVTD---DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVF 450 +++PT+ D DM + K E+F PV + K +D+ IE AN +GL AAVF Sbjct: 371 PT--YVQPTLVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVF 428 Query: 451 TNDINKALTVSSAMQAGTVWINCYNALN-AQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509 D+ K ++ G ++IN PFGG K SG RE + + + KT+ Sbjct: 429 GRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTI 488 Query: 510 TVKIPQK 516 K Sbjct: 489 VFNYKGK 495 >6DBB-A nrPDB Length = 511 Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats. Identities = 123/481 (25%), Positives = 221/481 (45%), Gaps = 23/481 (4%) Query: 52 GRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLAD 111 G +P G + + AD ++ + AA AF WR + A RG L+ + Sbjct: 27 GNALTARSPLDGATLATLAVDTPADAERKIDAAHDAFL---KWRTVPAPVRGELVRVFGN 83 Query: 112 LVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVD-GDYFT 170 ++ +A L + +L GK + ++Q +I + G + +++G+TI + + Sbjct: 84 VLREHKAELGRLVTLEAGKITSEGL-GEVQEMIDICDFAVGLSRQLYGLTIASERPGHRM 142 Query: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA- 229 PIGVCG I +NFP+ ++AW A A CG++VV KP+E+TPL+A+ L+++A Sbjct: 143 METWHPIGVCGVISAFNFPVAVWAWNAALAFVCGDSVVWKPSEKTPLTAIACHVLLQKAL 202 Query: 230 --------GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLK 281 G P + L G + + + ++ TGS +G+ + + + L Sbjct: 203 REFEKTHPGVAPAELGQLVLGMRDVGEVLTASKKVPVVSATGSVRMGQEVAKVLSQ-RLA 261 Query: 282 RVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSV 341 R LELGG + I+ ADLD V GQ CT R+ V S+ E+ + R Sbjct: 262 RGILELGGNNGMIVAPSADLDLVVRAVTFAAVGTAGQRCTTLRRLIVHRSLVEQLLPRIE 321 Query: 342 ERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG---RKGFF 398 + VG+P + T GP +D+ ++ + + + +G +++ GG+ + ++ Sbjct: 322 KAYASVKVGNPLEEGTLVGPLVDRASFDAMQKALADAREQGGEVK-GGERVDVGHADAYY 380 Query: 399 IEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKAL 458 + P + + + + E F P+ ++ + D+ I+ N GL +A+FTND+ +A Sbjct: 381 VRPAIV-RMPKQSAVVERETFAPILYVMVYDNFDDAIDVHNAVPQGLSSAIFTNDMREAE 439 Query: 459 TV--SSAMQAGTVWIN-CYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQ 515 ++ G V +N + FGG K +G GRE G + Y T T+ + Sbjct: 440 QFMSAAGSDCGIVNVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKAYMRRATNTINYSR 499 Query: 516 K 516 + Sbjct: 500 Q 500 >3SZA-A nrPDB Length = 469 Score = 416 bits (1070), Expect = e-116, Method: Composition-based stats. Identities = 124/451 (27%), Positives = 198/451 (43%), Gaps = 21/451 (4%) Query: 69 VQEADK-ADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLN 127 V + I +AV+ AR AFS G R R + L+ L L++ L + + Sbjct: 11 VPRGSHMSKISEAVKRARAAFSSG---RTRPLQFRIQQLEALQRLIQEQEQELVGALAAD 67 Query: 128 GGKPFLQAFYVDLQGVIKTFRYYA----GWADKIHGMTIPVDGDYFTFTRHEPIGVCGQI 183 K A+Y ++ V++ Y WA P + EP+GV I Sbjct: 68 LHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVI 127 Query: 184 IPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYG 243 WN+P + + A+ GN VV+KP+E + A + +I + + ++ G Sbjct: 128 GTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGV 186 Query: 244 PTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDY 303 P + D I +TGST VGK+I AA + +L VTLELGGKSP + + DLD Sbjct: 187 PETTELLKE--RFDHILYTGSTGVGKIIMTAAAK-HLTPVTLELGGKSPCYVDKNCDLDV 243 Query: 304 AVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQI 363 A + G F N GQ C A I + SI + V + + K G + + G I Sbjct: 244 ACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLK-EFYGEDAKKSRDYGRII 302 Query: 364 DKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQ 423 + + +++ LI EG K+ GG G +I PT+ ++V + +EEIFGPV Sbjct: 303 SARHFQRVMGLI-----EGQKVAYGGTG-DAATRYIAPTILTDVDPQSPVMQEEIFGPVL 356 Query: 424 EILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALN--AQS 481 I+ ++++E I+ N + L +F+++ + + +G V N Sbjct: 357 PIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSL 416 Query: 482 PFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512 PFGG SG G G+ +S ++ V+ Sbjct: 417 PFGGVGNSGMGSYHGKKSFETFSHRRSCLVR 447 >4KNA-A nrPDB Length = 495 Score = 411 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 145/459 (31%), Positives = 218/459 (47%), Gaps = 10/459 (2%) Query: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 T++FI+ W + G VF NP T E+V E A D+++AV +AR AF+ W + Sbjct: 10 TELFIDGAWVDGA-GPVFASRNPGTNERVWEGASASADDVERAVASARRAFA---AWSAL 65 Query: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157 D R ++ + A L+ + LATM GKP +A ++ + + Sbjct: 66 DLDARCTIVKRFAALLVERKEALATMIGRETGKPLWEART-EVASMAAKVDISITAYHER 124 Query: 158 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 217 G D RH P GV P+NFP + I PAL GNTVV KP+E P Sbjct: 125 TGEKRAPMADGVAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPG 184 Query: 218 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 277 A + ++AG P GV+N++ G G A+A+H ID + FTGS++ G L+ + G Sbjct: 185 VARATVEIWRDAGLPAGVLNLVQG-EKDTGVALANHRQIDGLFFTGSSDTGTLLHKQFGG 243 Query: 278 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY-EEF 336 + LE+GG +P ++ D+D AV A Q F + GQ CT RI V + + F Sbjct: 244 RPEIVLALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGDRF 303 Query: 337 VRRSVERAKRRVVG-SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRK 395 V R + A + DP G I + ++++ V GA K Sbjct: 304 VARLADVASKITASVFDADPQPFMGAVISARAASRLVAAQARLVGLGASPIIEMKQRDPA 363 Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN 455 F+ + +VT+ + EE FGP+ +I+R+ +D+ I RAN++ FGL A + +D Sbjct: 364 LGFVNAAIL-DVTNVRELPDEEHFGPLAQIVRYTDLDDAIARANDTAFGLSAGLLADDEQ 422 Query: 456 KALTVSSAMQAGTVWIN-CYNALNAQSPFGGFKMSGNGR 493 T A++AG V N N ++ +PFGG SGN R Sbjct: 423 AWHTFRRAIRAGIVNWNRPTNGASSAAPFGGAGRSGNHR 461 >3JU8-A nrPDB Length = 490 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 128/457 (28%), Positives = 197/457 (43%), Gaps = 10/457 (2%) Query: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDA 99 +I +W + G +P V + AD +D AV AAR AF W R Sbjct: 8 HYIAGQWL-AGQGETLESLDPVGQGVVWSGRGADATQVDAAVCAAREAF---PAWARRPL 63 Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 +R LL++ A ++ LA + GKP ++ ++ ++ + G Sbjct: 64 EQRIELLERFAATLKSRADELARVIGEETGKPLWESAT-EVTSMVNKVAISVQAFRERTG 122 Query: 160 MTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSA 219 D RH+P GV P+NFP + I PAL GN VV KP+E TP A Sbjct: 123 EKSGPLADATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTPKVA 182 Query: 220 LYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSN 279 +AG P GV+N++ G G G A+A+H G+D + FTGS+ G L+ G Sbjct: 183 ELTLKAWIQAGLPAGVLNLVQG-GRETGVALAAHRGLDGLFFTGSSRTGNLLHSQFGGQP 241 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY-EEFVR 338 K + LE+GG +P ++ ADLD AV Q F + GQ CT R+ V + + + + Sbjct: 242 QKILALEMGGNNPLVVEEVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALLA 301 Query: 339 RSVERAKRRVVGS-PFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 397 R V + VG P G I +L+ + + +GA+ Sbjct: 302 RLVAVSATLRVGRFDEQPAPFMGAVISLSAAEHLLKAQEHLIGKGAQPLLAMTQPIDGAA 361 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 457 + P + +V+ EE FGP+ +++R+ I AN + +GL A + ++ + Sbjct: 362 LLTPGIL-DVSAVAERPDEEFFGPLLQVIRYSDFAAAIREANATQYGLAAGLLSDSRERF 420 Query: 458 LTVSSAMQAGTVWIN-CYNALNAQSPFGGFKMSGNGR 493 +AG V N + +PFGG SGN R Sbjct: 421 EQFLVESRAGIVNWNKQLTGAASSAPFGGIGASGNHR 457 >4I3V-A nrPDB Length = 488 Score = 406 bits (1044), Expect = e-113, Method: Composition-based stats. Identities = 145/493 (29%), Positives = 222/493 (45%), Gaps = 26/493 (5%) Query: 33 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGS 92 + +++ + I + + V P V V +A A Sbjct: 11 IAVRHEPMRIAGRLVD--TDDRVEVRYPWNDTVVGTVPAGRAEHAREAFAIAAAYQP--- 65 Query: 93 VWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAG 152 ++ ER ++L A+ + + ++ + +L G + Y ++ F Sbjct: 66 ---KLTRYERQKILLATAEALAARKEEISDVITLELGISKADSLY-EVGRAFDVFTLAGQ 121 Query: 153 WADKIHGMT-----IPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTV 207 + G P FT EP+ I P+N PL M A K+APA+ N V Sbjct: 122 MCIRDDGEIFSCDLTPHGKARKIFTMREPLTAISAITPFNHPLNMVAHKVAPAIATNNCV 181 Query: 208 VIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEV 267 V+KP E TP++AL + ++ EAG PP +++++ G+ G + ++ +D + FTGS V Sbjct: 182 VVKPTELTPMTALLLADILYEAGLPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPV 241 Query: 268 GKLIQEAAGRSNLKRVTLELGGKSPNIIFA---DADLDYAVEQAHQGVFFNQGQCCTAGS 324 GKLI A ++ KR LELGG P II D DL A + A G N GQ CTA Sbjct: 242 GKLI---AANAHYKRQVLELGGNDPLIILNDLSDDDLARAADLAVAGATKNSGQRCTAVK 298 Query: 325 RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 RI +ES+ + FV +ERAKR G P D +T+ G I +K E + EGA Sbjct: 299 RILCQESVADRFVPLVLERAKRLRFGDPMDRSTDLGTVIHEKAAALFEERVMRAAEEGAD 358 Query: 385 LECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEV-IERANNSDF 443 + GR G + P V V + EE FGP+ I+R D+ I +N++ F Sbjct: 359 ILYH---PGRSGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDDDDATITLSNSTAF 415 Query: 444 GLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQS-PFGGFKMSGNG-REMGEFGLR 501 GL + V TND + + ++ GTV I + PFGG K SGNG +E ++ Sbjct: 416 GLSSGVCTNDYRRMQKYIAGLKVGTVNIWEVPGYRIEMSPFGGIKDSGNGYKEGVIEAMK 475 Query: 502 EYSEVKTVTVKIP 514 ++ VKT ++ P Sbjct: 476 SFTNVKTFSLPWP 488 >1AD3-A nrPDB Length = 452 Score = 398 bits (1024), Expect = e-111, Method: Composition-based stats. Identities = 115/442 (26%), Positives = 192/442 (43%), Gaps = 20/442 (4%) Query: 77 IDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAF 136 I V+ AR AF+ G R + L+ L ++ + ++ + + GK ++ Sbjct: 3 ISDTVKRAREAFNSGKT---RSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSY 59 Query: 137 YVDLQGVIK----TFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLM 192 Y ++ V++ T + WA+ + EP+GV I WN+P + Sbjct: 60 YEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNL 119 Query: 193 FAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIAS 252 + A+ GN V++KP+E + A + LI + + ++ G P + Sbjct: 120 TIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLKE 178 Query: 253 HIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGV 312 D I +TGST VGK++ AA + +L VTLELGGKSP + D DLD A + G Sbjct: 179 --RFDHIMYTGSTAVGKIVMAAAAK-HLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGK 235 Query: 313 FFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKIL 372 F N GQ C A I + SI + V + + K G + + G I+ + + ++ Sbjct: 236 FMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKD-FYGEDAKQSRDYGRIINDRHFQRVK 294 Query: 373 ELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMD 432 LI + G + +I PT+ +V + +EEIFGPV I+ ++++ Sbjct: 295 GLIDNQK------VAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLE 348 Query: 433 EVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINC--YNALNAQSPFGGFKMSG 490 E I+ N + L VF+N+ + + +G V N + PFGG SG Sbjct: 349 EAIQFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSG 408 Query: 491 NGREMGEFGLREYSEVKTVTVK 512 G G+ +S ++ VK Sbjct: 409 MGAYHGKKSFETFSHRRSCLVK 430 >3V9H-A nrPDB Length = 566 Score = 395 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 127/480 (26%), Positives = 222/480 (46%), Gaps = 28/480 (5%) Query: 51 SGRVFPVYNPAT-GEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKL 109 + V +P G +V + ADK+ ++KA++AA A W ++R ++ K Sbjct: 78 TSDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAA---RKEWDLKPIADRAQIFLKA 134 Query: 110 ADLVE--RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM---TIPV 164 AD++ R +LA GK +QA +I FR+ A +A ++ G ++P Sbjct: 135 ADMLSGPRRAEILAKTMV-GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPP 193 Query: 165 DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGA 224 + + E G I P+NF + APAL GN V+ KP++ L++ + Sbjct: 194 STNSTVYRGLE--GFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYR 250 Query: 225 LIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS-----N 279 +++EAG PP +I +P GP G + S + I FTGS K + + ++ Sbjct: 251 ILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHT 310 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRR 339 R+ E GGK+ + + AD++ V + F GQ C+A +R++V S++ + R Sbjct: 311 FPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACARLYVPHSLWPQIKGR 370 Query: 340 SVERAKRRVVGSPF-DPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLGRKGF 397 +E R VG P D T ID K + +I + ++ + + + GGK G+ Sbjct: 371 LLEEHSRIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGY 430 Query: 398 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTM--DEVIERANN-SDFGLVAAVFTNDI 454 F+EP + + I KEEIFGPV + + E ++ ++ + +GL AVF+ D Sbjct: 431 FVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDK 490 Query: 455 NKALTVSSAMQ--AGTVWINC--YNALNAQSPFGGFKMSGNGRE-MGEFGLREYSEVKTV 509 + + ++ AG +IN ++ Q PFGG + SG + G + ++ + + Sbjct: 491 DVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVI 550 >4LGZ-A nrPDB Length = 563 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 126/466 (27%), Positives = 217/466 (46%), Gaps = 27/466 (5%) Query: 64 EQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVE--RDRAVLA 121 +V + ADKA +++A+ AA A W ++R ++ K AD++ R VLA Sbjct: 89 HKVAKFCYADKALLNRAIDAALAA---RKEWDLKPMADRAQVFLKAADMLSGPRRAEVLA 145 Query: 122 TMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGM---TIPVDGDYFTFTRHEPIG 178 GK +QA +I FR+ A +A ++ G ++P ++ + E G Sbjct: 146 KTMV-GQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLE--G 202 Query: 179 VCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINI 238 I P+NF + APAL GN V+ KP++ L++ + +++EAG PP +I Sbjct: 203 FVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQF 261 Query: 239 LPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS-----NLKRVTLELGGKSPN 293 +P GPT G + S + I FTGS K + ++ R+ E GGK+ + Sbjct: 262 VPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFH 321 Query: 294 IIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPF 353 + + AD+D V + F GQ C+A SR++V +S++ + R +E R VG P Sbjct: 322 FVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPA 381 Query: 354 -DPTTEQGPQIDKKQYNKILELIQSGVAEGA-KLECGGKGLGRKGFFIEPTVFSNVTDDM 411 D T ID K + +I + ++ + + + GG+ G+++EP + + Sbjct: 382 EDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQE 441 Query: 412 RIAKEEIFGPVQEILRFKTMD--EVIERANN-SDFGLVAAVFTNDINKALTVSSAMQ--A 466 I KEEIFGPV + + E ++ ++ + +GL AVF D + ++ A Sbjct: 442 PIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAA 501 Query: 467 GTVWINC--YNALNAQSPFGGFKMSGNGRE-MGEFGLREYSEVKTV 509 G +IN ++ Q PFGG + SG + G + ++ + + Sbjct: 502 GNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVI 547 >4QGK-A nrPDB Length = 461 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 115/439 (26%), Positives = 189/439 (43%), Gaps = 22/439 (5%) Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V+ R AF G R R + L+ L +V+ + T + + K + ++ Sbjct: 6 VRRVRQAFLSG---RSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEV 62 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGD-----YFTFTRHEPIGVCGQIIPWNFPLLMFAW 195 V+ + + PV + + + +P+GV I WN+P ++ Sbjct: 63 ITVLGEIDFMLENLPE-WVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ 121 Query: 196 KIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIG 255 + A+ GN V+IKP+E + +A + L+ + + ++ G + Sbjct: 122 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQ--R 178 Query: 256 IDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFN 315 D I +TG+T VGK++ EAA + +L VTLELGGKSP I D DLD + G + N Sbjct: 179 FDHIFYTGNTAVGKIVMEAAAK-HLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMN 237 Query: 316 QGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELI 375 GQ C A I E S+ + V + E K G + + I+ + + +IL L+ Sbjct: 238 CGQTCIAPDYILCEASLQNQIVWKIKETVK-EFYGENIKESPDYERIINLRHFKRILSLL 296 Query: 376 QSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVI 435 EG K+ GG+ +I PTV ++V ++ +EEIFGP+ I+ K +DE I Sbjct: 297 -----EGQKIAFGGET-DEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAI 350 Query: 436 ERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNA--QSPFGGFKMSGNGR 493 N + L VF+++ + +G V N PFGG SG G Sbjct: 351 NFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGA 410 Query: 494 EMGEFGLREYSEVKTVTVK 512 G+ +S + +K Sbjct: 411 YHGKHSFDTFSHQRPCLLK 429 >4OE4-A nrPDB Length = 580 Score = 366 bits (939), Expect = e-101, Method: Composition-based stats. Identities = 130/487 (26%), Positives = 217/487 (44%), Gaps = 35/487 (7%) Query: 40 IFINNEWQ-NSESGRVFPVYNPAT-GEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97 + IN E ++ +FP NPA + + V +A + D+ + A + A W + Sbjct: 62 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDV---MNAVKAAKDAKKDWYNL 118 Query: 98 DASERGRLLDKLADLVE-RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADK 156 +R + K ADL+ + R + L GK QA + + FRYY +A Sbjct: 119 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 178 Query: 157 IHGMTIPVDGDYFTFTR--HEPI-GVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213 ++ PV+ T+ + + P+ G + P+NF + APAL GNTVV KP++ Sbjct: 179 LYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 236 Query: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273 LS + +++EAG P GVIN +PG + + + FTGST V K + Sbjct: 237 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 296 Query: 274 A-------AGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRI 326 + R+ E GGK+ +++ A++ +AV +G F QGQ C+A SR+ Sbjct: 297 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 356 Query: 327 FVEESIYEEFVRRS------VERAKRRVVGSPFDPTT---EQGPQIDKKQYNKILELIQS 377 ++ ES EEF+ SP GP I ++ ++K++++I+ Sbjct: 357 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 416 Query: 378 GVAEG-AKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMD--EV 434 + ++ GG+ +G+F+ PTV D E FGP+ + + + E+ Sbjct: 417 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 476 Query: 435 IERA-NNSDFGLVAAVFTNDINKALTVSSAMQ--AGTVWIN--CYNALNAQSPFGGFKMS 489 + N S + L A+F D ++ AG +IN C A+ +Q FGG +MS Sbjct: 477 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 536 Query: 490 GNGREMG 496 G + G Sbjct: 537 GTDDKAG 543 >5UCD-A nrPDB Length = 457 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 122/446 (27%), Positives = 204/446 (45%), Gaps = 23/446 (5%) Query: 73 DKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPF 132 A ID A + F+ D R + L++L + V ++ L + + + GKP Sbjct: 26 SPAKIDSLFSAQKAYFATR---ATADVGFRKQSLERLKEAVINNKEALYSALAEDLGKPK 82 Query: 133 LQAFYVDLQGVIKTFRYYAGWADK-IHGMTIPVD---GDYFTFTRHEPIGVCGQIIPWNF 188 ++ V+ + D+ + +++P + EP GV I P+N+ Sbjct: 83 DVVDLAEIGAVLHEIDFALAHLDEWVAPVSVPSPDIIAPSECYVVQEPYGVTYIIGPFNY 142 Query: 189 PLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGA 248 P+ + + A+ GNT +IKP+E TP ++ + +I EA F P + ++ G G + Sbjct: 143 PVNLTLTPLIGAIIGGNTCIIKPSETTPETSAVIEKIIAEA-FAPEYVAVIQG-GRDENS 200 Query: 249 AIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQA 308 + S D I FTGS VGK++ +AA + +L V LELGGK P I+ DADLD V Q Sbjct: 201 HLLSLP-FDFIFFTGSPNVGKVVMQAAAK-HLTPVVLELGGKCPLIVLPDADLDQTVNQL 258 Query: 309 HQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQY 368 G F N GQ A ++V S+ + + R VER K G + ++Q Sbjct: 259 MFGKFINSGQTXIAPDYLYVHYSVKDALLERLVERVKTE-----LPEINSTGKLVTERQV 313 Query: 369 NKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRF 428 +++ L+++ +G L G + TV V + + EE+FGP+ +L F Sbjct: 314 QRLVSLLEA--TQGQVLV--GSQADVSKRALSATVVDGVEWNDPLMSEELFGPILPVLEF 369 Query: 429 KTMDEVIERANN-SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCY--NALNAQSPFGG 485 ++ I++ N L VF D++ A + + +Q+G +N +A + PFGG Sbjct: 370 DSVRTAIDQVNKHHPKPLAVYVFGKDMDVAKGIINQIQSGDAQVNGVMLHAFSPYLPFGG 429 Query: 486 FKMSGNGREMGEFGLREYSEVKTVTV 511 SG G G F ++ K+V + Sbjct: 430 IGASGMGEYHGHFSYLTFTHKKSVRI 455 >4H7N-A nrPDB Length = 474 Score = 354 bits (909), Expect = 6e-98, Method: Composition-based stats. Identities = 133/469 (28%), Positives = 210/469 (44%), Gaps = 21/469 (4%) Query: 53 RVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADL 112 + V NP TG+ + + + AR A S W+ + R L + Sbjct: 6 KTIEVRNPRTGKFDYVIIPPPPRLLAQQCNRARRA---QSRWQELGVEGRITTLQQWKQA 62 Query: 113 VERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFT 172 + R L + G+ L +++ + + + G A ++ + F Sbjct: 63 ILSRREQLTEALVNDTGR--LSITVLEIDSFLASIDRWCGLAPELLQTSAKNTSIPFIAL 120 Query: 173 RH--EPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 230 + P + G I PWNFPL + PAL G VV+KP+E P ++ L+ Sbjct: 121 QQSLVPYPLVGVISPWNFPLTLSMIDTIPALLAGCAVVVKPSEIAP---RFVAPLLMALN 177 Query: 231 FPPG---VINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLEL 287 P V+ + G G GA + ++ +D + FTGS G+ + E A R LEL Sbjct: 178 TVPELRDVLIFVEGGG-ETGANLINY--VDFVCFTGSVATGREVAETAAR-RFIPAYLEL 233 Query: 288 GGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRR 347 GGK P I+ A+L+ A G N GQ C + RI+V ES +EEF + + +A R Sbjct: 234 GGKDPAIVLESANLELATSAILWGAVVNTGQSCLSIERIYVAESKFEEFYHQLIAKAHRL 293 Query: 348 VVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG-RKGFFIEPTVFSN 406 + P GP I +KQ I + I V +GA + CGGK G++ PTV +N Sbjct: 294 QLAYPLVEDGAIGPIIAEKQAGIINDHILDAVEKGAVIHCGGKVEELGGGWWCRPTVMTN 353 Query: 407 VTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQA 466 V M++ EE FGP+ ++ F ++E + AN++ +GL AAVF ++AL V+ + A Sbjct: 354 VNHSMKVMTEETFGPIMPVMPFPDVEEAVYLANDTIYGLSAAVFAGSEDEALKVARQLNA 413 Query: 467 GTVWINC--YNALNAQSPFGGFKMSGN-GREMGEFGLREYSEVKTVTVK 512 G + IN A+ + F SG G +G GL+ + + +K Sbjct: 414 GAISINDAALTAMMHEGEKNAFNFSGLGGSRVGAAGLKRFLRKQAFLIK 462 >4IDS-A nrPDB Length = 563 Score = 334 bits (856), Expect = 8e-92, Method: Composition-based stats. Identities = 124/506 (24%), Positives = 201/506 (39%), Gaps = 28/506 (5%) Query: 20 MASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDK 79 +ASL P P I G V P + A Sbjct: 52 LASLADHPIDLP--------HVIGGR-HRMGDGERIDVVQPHRHA--ARLGTLTNATHAD 100 Query: 80 AVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERD-RAVLATMESLNGGKPFLQAFYV 138 A A A S S W + ER + + ADL+ R +A L K QA Sbjct: 101 AAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEID 160 Query: 139 DLQGVIKTFRYYAGWADK-IHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKI 197 + +I +R+ +A + + I G++ G I P+NF + Sbjct: 161 AVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPT 220 Query: 198 APALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGID 257 APAL GNTV+ KP+ L+A L++ AG PPGVIN++ G G + + Sbjct: 221 APALM-GNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLA 279 Query: 258 KIAFTGSTEVGKLIQEAAG-----RSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGV 312 I FTGST + + G + R+ E GGK + A A D +G Sbjct: 280 GIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGA 339 Query: 313 FFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKIL 372 F QGQ C+A SR F+ S+++ + +A G D + G ID++ + K + Sbjct: 340 FDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNV 399 Query: 373 ELIQSGVAEGA-KLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTM 431 + I+ A + GG+ +G+F+ PTV + E FGP+ + + Sbjct: 400 DAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDE 459 Query: 432 --DEVIERAN-NSDFGLVAAVFTNDINKALTVSSAMQ--AGTVWINC--YNALNAQSPFG 484 +++++ + S + L AV +D LT ++ AG ++N A+ + PFG Sbjct: 460 RYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFG 519 Query: 485 GFKMSGNGREMG-EFGLREYSEVKTV 509 G + S + G L ++ +++ Sbjct: 520 GARGSDTNDKAGSPLNLLRWTSARSI 545 >5NNO-A nrPDB Length = 546 Score = 310 bits (795), Expect = 9e-85, Method: Composition-based stats. Identities = 109/454 (24%), Positives = 187/454 (41%), Gaps = 38/454 (8%) Query: 81 VQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL 140 V R AF+ D +R ++L L +LVE + + + + +++ Sbjct: 21 VSKCREAFNDD---ANRDLKKRKQVLRSLLNLVEENTDEFCKAIHRDRRRHRDETVVMEI 77 Query: 141 QGVIKTFRYYAGWADKIHGMTIPVDGDYFTF----TRHEPIGVCGQIIPWNFPLLMFAWK 196 + + D+ P ++EP+GV I WN+PLL+ Sbjct: 78 LPLRNEVWHLIEHMDEYVKPVKPTMEGAAALDDCELQYEPLGVVLVIGTWNYPLLLILQP 137 Query: 197 IAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGI 256 + AL GNT VIKP+E P +A + L+ + V+ I+ G A + Sbjct: 138 LLGALAAGNTAVIKPSELAPATAELLTKLLPKY-VSSDVVGIVNGGVSETTAVLKE--RF 194 Query: 257 DKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADA--DLDYAVEQAHQGVFF 314 D I +TGS V +++ AA + +L VTLELGGKSP ++ ++ E+ G Sbjct: 195 DHILYTGSARVAEIVMAAAAK-HLTPVTLELGGKSPVVVDDTCADNMKVVAERIMWGKII 253 Query: 315 NQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFD----------------PTTE 358 N GQ A + VE+S+ V E K +G F ++ Sbjct: 254 NAGQTSIAPDYVVVEKSMESVLVDALAEARKAM-LGDKFLKVLKGELLVKQKQQFLEESD 312 Query: 359 QGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEI 418 ++ + +++E + +G K+ GG+ I PT+ +N+ + +EEI Sbjct: 313 YPRIVNASHFQRLMEFM-----KGGKVAVGGEA-DEATLTIAPTILTNIDPTHPVMQEEI 366 Query: 419 FGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALN 478 FGP+ +L ++ ++++ N+ + L VF+N+ V S +G V +N Sbjct: 367 FGPILPVLTYENEKDILKIINSREKPLALYVFSNNKRFIRGVESRTSSGAVVVNDVVVHA 426 Query: 479 A--QSPFGGFKMSGNGREMGEFGLREYSEVKTVT 510 PFGG SG G G + +S + V Sbjct: 427 GADGLPFGGVGRSGMGAYHGRYSFETFSHRRPVM 460 >2Y53-A nrPDB Length = 534 Score = 265 bits (678), Expect = 3e-71, Method: Composition-based stats. Identities = 109/481 (22%), Positives = 190/481 (39%), Gaps = 44/481 (9%) Query: 39 KIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMD 98 K + +W + +G + +P TG + V + D+ +A AR G+ R + Sbjct: 9 KNHVAGQWI-AGTGAGITLTDPVTGVALVRVSS-EGLDLARAFSFARE--DGGAALRALT 64 Query: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158 ++R L + L++ R + + N G + VD+ G I T YYA + Sbjct: 65 YAQRAARLADIVKLLQAKRGDYYAIATANSGTTRNDSA-VDIDGGIFTLSYYAKLGASLG 123 Query: 159 GMTIPVDGDYFTFTRHEPI----------GVCGQIIPWNFPLLMFAWKIAPALCCGNTVV 208 + DG + ++ GV I +NFP K APAL G V+ Sbjct: 124 EVHALRDGSAESLSKDRSFSAQHVLSPTRGVALFINAFNFPSWGLWEKAAPALLSGVPVI 183 Query: 209 IKPAEQTPLSALYMGALIKEAG-FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEV 267 +KPA T M A + +AG PPG ++I+ G I S D ++FTGS + Sbjct: 184 VKPATATAWLTQRMVADVVDAGILPPGALSIICGSSAGLLDQIRS---FDVVSFTGSADT 240 Query: 268 GKLI-QEAAGRSNLKRVTLELGGKSPNIIFADAD-----LDYAVEQAHQGVFFNQGQCCT 321 + A R+ ++ + I+ ADA D +++ + + GQ CT Sbjct: 241 AATLRAHPAFVQRGARLNVQADSLNSAILCADATPDTPAFDLFIKEVVREMTVKSGQKCT 300 Query: 322 AGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAE 381 A R FV E+ E + + + VG+P + G + ++QY +L I + E Sbjct: 301 AIRRAFVPEAALEPVLEALKAKLAKITVGNPRNDAVRMGSLVSREQYENVLAGIA-ALRE 359 Query: 382 GAKLECGGKGL------GRKGFFIEPTVF-SNVTDDMRIAKE-EIFGPVQEILRFK---- 429 A L + + P +F N D+ + + E+FGPV + ++ Sbjct: 360 EAVLAYDSSAVPLIDADANIAACVAPHLFVVNDPDNATLLHDVEVFGPVASVAPYRVTTD 419 Query: 430 ----TMDEVIERANNSDFGLVAAVFTNDINKALTVSSAM--QAGTVWINCYNALNAQSPF 483 + A LVA++++ND ++ + G V + ++Q+ Sbjct: 420 TNALPEAHAVALARRGQGSLVASIYSNDDAHLGRLALELADSHGRVHAISPSVQHSQTGH 479 Query: 484 G 484 G Sbjct: 480 G 480 >3V4C-A nrPDB Length = 528 Score = 253 bits (647), Expect = 1e-67, Method: Composition-based stats. Identities = 104/467 (22%), Positives = 165/467 (35%), Gaps = 45/467 (9%) Query: 36 KYTKIFINNEWQN-SESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVW 94 K + EW + + + P + PA V V +++A +AA AF Sbjct: 28 PKGKHLVAGEWLDGAGTFASAPAHGPAHDFAVGTV-----ELVNRACEAAEEAFWTYGYS 82 Query: 95 RRMDASERGRLLDKLADLVERDRAVLATMESLNGGKP--FLQAFYVDLQGVIKTFRYYAG 152 R ER L +AD +E + + S G P L G ++ F + Sbjct: 83 SR---KERAAFLRAIADEIEARAEAITEIGSQETGLPEARLNGERGRTTGQLRLFADHIE 139 Query: 153 WADKIHGMTIPVDGDYFTFTRHE------PIGVCGQIIPWNFPLLM--FAWKIAPALCCG 204 D + + R E P+G NFPL A AL G Sbjct: 140 KGDYLDRRVDAAMPERQPAPRQEIRLVQRPVGPVAVFGASNFPLAFSTAGGDTAAALAAG 199 Query: 205 NTVVIKPAEQTPLSALYMGALIKEA----GFPPGVINILPGYGPTAGAAIASHIGIDKIA 260 VV+K P + + + A G PGV +++ G G A+ H I + Sbjct: 200 CPVVVKGHSAHPGTGEIVAEAVDAAIRKTGVHPGVFSLIQGGSRDVGHALVQHPHIKAVG 259 Query: 261 FTGSTEVGKLIQE-AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQG----VFFN 315 FTGS G+ + + A R ELG +P + +A L E QG + Sbjct: 260 FTGSLAGGRALFDLCAARPEPIPFFGELGSVNPMFLLPEA-LKARAETLGQGWAGSLTMG 318 Query: 316 QGQCCTAGS-RIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILEL 374 GQ CT + +E + + F +VE + P T I K + Sbjct: 319 AGQFCTNPGIAVVIEGADADRFTTAAVEALAKV------APQTMLTDGIAKAYRDGQARF 372 Query: 375 -IQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDE 433 ++ V E G+ F T + D + EE+FGP+ ++R + E Sbjct: 373 ATRNAVKPLLATESSGRDASPNLF---ETTGAQFLADHALG-EEVFGPLGLVVRVGSPAE 428 Query: 434 VIERANNSDFGLVAAVFTN--DINKALTVSSAMQ--AGTVWINCYNA 476 + E A L A + + D+ A + ++ AG V +N + Sbjct: 429 MEELARGFQGQLTATIHMDAGDLETARRLRPVLERKAGRVLVNGFPT 475 >5DBV-A nrPDB Length = 445 Score = 223 bits (568), Expect = 2e-58, Method: Composition-based stats. Identities = 94/459 (20%), Positives = 162/459 (35%), Gaps = 58/459 (12%) Query: 75 ADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQ 134 D+++A++AA+ A + +M +R +++ + LA M G Sbjct: 16 DDMNQAIEAAKEAQLVVK---KMSMDQREKIISAIRKKTIEHAETLARMAVEETG----- 67 Query: 135 AFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHE--PIGVCGQIIPWNFPLLM 192 ++ I + A +T T E P GV G I P P Sbjct: 68 --MGNVGHKILKHQLVAEKTPGTEDITTTAWSGDRGLTLVEMGPFGVIGAITPCTNPSET 125 Query: 193 FAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPP-GVINILPGYGP---TAGA 248 L GNTVV P ++ + LI EA G +NI + Sbjct: 126 IICNTIGMLAGGNTVVFNPHPAAIKTSNFAVQLINEASLSAGGPVNIACSVRKPTLDSSK 185 Query: 249 AIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQA 308 + SH I IA TG V + ++ KR G P ++ AD+ A E Sbjct: 186 IMMSHQDIPLIAATGGPGVVTAVLQS-----GKRGIGAGAGNPPVLVDETADIRKAAEDI 240 Query: 309 HQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGP-QIDKKQ 367 G F+ A + ++I E + V+ EQG I K+Q Sbjct: 241 INGCTFDNNLPAIAEKEVVAIDAIANELMNYMVK---------------EQGCYAITKEQ 285 Query: 368 YNKILELIQSGVAEGAKLECGGKG----LGRKGFFIEPTVFSNV---TDDMRIAKEEIFG 420 K+ L+ + +G C GK LG G + + + + + EE+ Sbjct: 286 QEKLTNLVIT--PKGLNRNCVGKDARTLLGMIGIDVPSNIRCIIFEGEKEHPLISEELMM 343 Query: 421 PVQEILRFKTMDEVIERANNSDFG--LVAAVFTNDINKALTVSSAMQAGTVWINCYNALN 478 P+ I+R K+ D+ +E+A + G A + + ++++ T + A+ + N + Sbjct: 344 PILGIVRAKSFDDAVEKAVWLEHGNRHSAHIHSKNVDRITTYAKAIDTAILVKNAPSYAA 403 Query: 479 AQSPFGGFK------MSGNGREMGEFGLREYSEVKTVTV 511 FGG S G G +++ + + Sbjct: 404 IG--FGGEGFCTFTIASRTGE--GLTSASTFTKRRRCVM 438 >6D97-A nrPDB Length = 547 Score = 211 bits (537), Expect = 7e-55, Method: Composition-based stats. Identities = 99/488 (20%), Positives = 179/488 (36%), Gaps = 43/488 (8%) Query: 25 LLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAA 84 + P + F+ W S + +P G++ +V E +I +++ Sbjct: 32 VSPQEVSGSSPAEVQNFVQGSWTASANWNWI--VDPLNGDKFIKVAEVQGTEIKSFMESL 89 Query: 85 RLAFSLGSVWRRMDASER----GRLLDKLADLVERDR--AVLATMESLNGGKPFLQAFYV 138 G + A ER G + K A ++ + A + K + QA Sbjct: 90 SKCPKHGLH-NPLKAPERYLMYGDISAKAAHMLGQPTVLDFFAKLIQRVSPKSYQQAL-A 147 Query: 139 DLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFT---RHEPIGVCGQIIPWNFPLLMFAW 195 ++Q K + G + + V G++ P G I P+NFPL + Sbjct: 148 EVQVSQKFLENFCGDQVRFLARSFAVPGNHLGQRSNGYRWPYGPVAIITPFNFPLEIPLL 207 Query: 196 KIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIG 255 ++ AL GN V+K + + M L+ + G P ++ + G + Sbjct: 208 QLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHDCGLPAEDMDFINSDGAVMNKLLLE-AN 266 Query: 256 IDKIAFTGSTEVGKLIQEAAGRSNLK-RVTLELGGKSPNIIFAD-ADLDYAVEQAHQGVF 313 FTGS+ V + + ++LK RV LE G I+ D ++DY Q + Sbjct: 267 PKMTLFTGSSRVAEKLA-----ADLKGRVKLEDAGFDWKILGPDVQEVDYVAWVCDQDAY 321 Query: 314 FNQGQCCTAGSRIFVEESIYEE-FVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKIL 372 GQ C+A S +F+ ++ + + + ++RR + GP + I Sbjct: 322 ACSGQKCSAQSVLFMHKNWSSSGLLEKMKKLSERRKL-----EDLTIGPVLTVTTEAMIE 376 Query: 373 ELIQSGVAEGAKLECGGKGLGRKGF-----FIEPT-VFSNVTD-----DMRIAKEEIFGP 421 + G+K+ GG+ L ++PT VF + + + + +EIFGP Sbjct: 377 HMNNLLKIRGSKVLFGGEPLANHSIPKIYGAMKPTAVFVPLEEILKSGNFELVTKEIFGP 436 Query: 422 VQEILRF--KTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINC---YNA 476 Q + + ++ V+E + L AA+ +ND V GT + Sbjct: 437 FQVVTEYSEDQLELVLEACERMNAHLTAAIVSNDPLFLQDVLGRSVNGTTYAGIRARTTG 496 Query: 477 LNAQSPFG 484 FG Sbjct: 497 APQNHWFG 504 >1EZ0-A nrPDB Length = 510 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 97/469 (20%), Positives = 172/469 (36%), Gaps = 49/469 (10%) Query: 48 NSESGRVFPVYNPATGEQV-CEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLL 106 N ++ VF N TGE + + +++ QAA A + +RR++ S+R LL Sbjct: 2 NPQTDNVFYATNAFTGEALPLAFPVHTEVEVN---QAATAAAKVARDFRRLNNSKRASLL 58 Query: 107 DKLADLVERDRAVL--------ATMESLNGGKPFLQAFYVDL-QGVIKTFRYYAGWADKI 157 +A +E + A E G+ A + L V+ + Y+ D Sbjct: 59 RTIASELEARSDDIIARAHLETALPEVRLTGEIARTANQLRLFADVVNSGSYHQAILDTP 118 Query: 158 HGMTIPVDGDYFTFTRHE--PIGVCGQIIPWNFPLLMFA--WKIAPALCCGNTVVIKPAE 213 + P+ R + +G NFPL A A AL G V++K Sbjct: 119 NPTRAPLPKPD---IRRQQIALGPVAVFGASNFPLAFSAAGGDTASALAAGCPVIVKGHT 175 Query: 214 QTPLSALYMGALIKEA----GFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269 P ++ + I++A P + +L G G A+ SH I + FTGS G+ Sbjct: 176 AHPGTSQIVAECIEQALKQEQLPQAIFTLLQGNQRALGQALVSHPEIKAVGFTGSVGGGR 235 Query: 270 LIQEAAG-RSNLKRVTLELGGKSPNIIFADADLDYA--VEQAHQGVFFNQGQCCTAGSRI 326 + A R ELG +P IF A A +Q + GQ CT + Sbjct: 236 ALFNLAHERPEPIPFYGELGAINPTFIFPSAMRAKADLADQFVASMTMGCGQFCTKPGVV 295 Query: 327 FVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLE 386 F ++ + +E A+ + P+T P I +++ + G +G + Sbjct: 296 F---ALNTPETQAFIETAQSLI--RQQSPSTLLTPGIRDSYQSQV---VSRGSDDGIDVT 347 Query: 387 CGGKGLGRKGFFIEPTVFSNVTDD---MRIAKEEIFGPVQEILRFKTMDEVIERANNSDF 443 + + +F +++ +EEIFGP I+ + + +++ + Sbjct: 348 FS----QAESPCVASALFVTSSENWRKHPAWEEEIFGPQSLIVVCENVADMLSLSEMLAG 403 Query: 444 GLVAAVFTN--DINKALTVSSAMQ--AGTVWINCYNALNAQSP---FGG 485 L A + D + + ++ AG + N + GG Sbjct: 404 SLTATIHATEEDYPQVSQLIPRLEEIAGRLVFNGWPTGVEVGYAMVHGG 452 >5J7I-A nrPDB Length = 488 Score = 193 bits (491), Expect = 1e-49, Method: Composition-based stats. Identities = 92/437 (21%), Positives = 152/437 (34%), Gaps = 52/437 (11%) Query: 75 ADID-KAVQAAR----LAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGG 129 DID +++Q R A + + +M SE ++++ +A+ + LA M G Sbjct: 26 RDIDLQSIQEVRNYLEEAKAAQKILEKMTQSEIDKIVESMANAAREEAGRLAAMAVEETG 85 Query: 130 KPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFP 189 F L+ + Y D I D + + +P+G+ IIP P Sbjct: 86 --FGNVEDKTLKNLFAANDVYNSIKDVKTVGIIRRDEENRVWEIAQPVGIVAGIIPSTNP 143 Query: 190 LLMFAWKIAPALCCGNTVVIKPAE----QTPLSALYMGALIKEAGFPPGVINILPGYGPT 245 +K A+ N +V P T +A M + AG P G+I+ + Sbjct: 144 TSTVIFKALIAVKARNAIVFSPHPSAAKCTAEAARIMQEAAERAGAPKGLISCITQPTMA 203 Query: 246 AGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAV 305 A + H D I TG + K A S+ K G P I A++ AV Sbjct: 204 ATNELMKHKLTDVILATGGPGLVK-----AAYSSGKPAYGVGPGNVPVYIHESANIAKAV 258 Query: 306 EQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDK 365 + Q F+ G C + + V+ESI E+ V ++ +++ Sbjct: 259 QLIIQSKTFDYGTICASEQALLVDESIKEKVVAELKQQGAYF---------------LNE 303 Query: 366 KQYNKILELIQSGVAEGAKLECGGKGL----GRKGFFIEPTVFSNVTDDMRIAKEEIF-- 419 ++ K+ +I + AK+ GK G I V V ++ + KE F Sbjct: 304 EEKQKVASIIMVNGSLNAKIV--GKAPQVIAEMAGIEIPSDVKLLVAEETEVGKEYPFSI 361 Query: 420 ---GPVQEILRFKTMDEVIERANNS----DFGLVAAVFTNDINKALTVSSAMQAGTVWIN 472 P+ K M+E E A G + D + AG + +N Sbjct: 362 EKLSPILAFYIVKGMEEASELAQKLLEVGGLGHTVGIHAEDEKVIEAYTIDKPAGRIVVN 421 Query: 473 CYNALNAQSPFGGFKMS 489 FGG + Sbjct: 422 AGTT------FGGIGAT 432 >5JFN-A nrPDB Length = 524 Score = 157 bits (397), Expect = 1e-38, Method: Composition-based stats. Identities = 70/413 (16%), Positives = 139/413 (33%), Gaps = 54/413 (13%) Query: 98 DASERGRLLDKLADLV--ERDRAVLATMESLNGG------KPFLQAFYVDLQGVIKTFRY 149 S+R R + + D++ + ++ M G K + I+ Sbjct: 112 SMSDRARFVQGIRDVILNQDTLEKMSRMAVEETGMGNYEHKLIKNRLAGEKTPGIEDLTT 171 Query: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209 A D + T + P GV G I P P L GN+VV Sbjct: 172 DAFSGD-----------NGLTLVEYSPFGVIGAITPTTNPTETIVCNSIGMLAAGNSVVF 220 Query: 210 KPAEQTPLSALYMGALIKE----AGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 265 P + +L + LI + G P ++ + A+ +H + + TG Sbjct: 221 SPHPRARQVSLLLVRLINQKLAALGAPENLVVTVEKPSIENTNAMMAHPKVRMLVATGGP 280 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 + K + S K+ G P ++ A+++ A G F+ A Sbjct: 281 AIVKAVL-----STGKKAIGAGAGNPPVVVDETANIEKAACDIVNGCSFDNNLPXVAEKE 335 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 I I + + ++ + P ++ +L+ + G + Sbjct: 336 IIAVAQIADYLIFNL-KKNGAYEIKDPAV-------------LQQLQDLVLTAKG-GPQT 380 Query: 386 ECGGKG----LGRKGFFIEPT---VFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERA 438 +C GK L + G ++ + + V + +EE+ P+ ++R +T+D+ I+ A Sbjct: 381 KCVGKSAVWLLSQIGISVDASIKIILMEVPREHPFVQEELMMPILPLVRVETVDDAIDLA 440 Query: 439 NNSDFG--LVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMS 489 + A + + D+ K ++ +Q N + + GG S Sbjct: 441 IEVEHDNRHTAIMHSTDVRKLTKMAKLIQTTIFVKNGPSYAGLGA--GGEGYS 491 >3MY7-A nrPDB Length = 452 Score = 155 bits (393), Expect = 3e-38, Method: Composition-based stats. Identities = 79/433 (18%), Positives = 144/433 (33%), Gaps = 38/433 (8%) Query: 69 VQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNG 128 + + A++D + + A + + ++ + + R LA Sbjct: 1 MPVTNMAELDAMIARVKKA---QEEFATYSQEQVDKIFRAASLAANQARIPLAQQAVEES 57 Query: 129 GKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNF 188 G ++ + + Y + D+ + D + T T EP+G+ I+P Sbjct: 58 GMGIVEDKVIKNHFASEFI--YNKYKDEQTCGILEEDDNLGTMTIAEPVGIICGIVPTTN 115 Query: 189 PLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA----GFPPGVINILPGYGP 244 P +K +L N ++ P + S L+ +A G P +I + Sbjct: 116 PTSTAIFKSLISLKTRNGIIFSPHPRAKNSTNDAAKLVLDAAVAAGAPKDIIGWIDQPSV 175 Query: 245 TAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYA 304 A+ H I I TG A S+ K G P +I AD+ A Sbjct: 176 ELSNALMKHDDIALILATGGPG-----MVKAAYSSGKPAIGVGAGNVPVVIDETADIKRA 230 Query: 305 VEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQID 364 V F+ G C + + V + +Y+E R K V+ + ID Sbjct: 231 VASVLMSKTFDNGVVCASEQAVIVVDEVYDEVKERF-ASHKAHVLSKTDADKVRKVLLID 289 Query: 365 KKQYNKILELIQSGVAE--GAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPV 422 KI+ + +AE G K+ K L +G V+ D A E++ P Sbjct: 290 GALNAKIVGQPATAIAEMAGVKVPADTKVLIGEG-------LGKVSYDDAFAHEKL-SPT 341 Query: 423 QEILRFKTMDEVIERANNSD----FGLVAAVFTN---DINKALTVSSAMQAGTVWINCYN 475 + R ++ + +A G + ++TN + ++ M+ + IN Sbjct: 342 LGMFRADNFEDAVAQAVTMVEIGGIGHTSGLYTNQDVNADRIRYFGDKMKTARILINIPT 401 Query: 476 ALNAQSPFGGFKM 488 GG Sbjct: 402 T------HGGIGD 408 >5UJU-A nrPDB Length = 576 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 99/487 (20%), Positives = 169/487 (34%), Gaps = 74/487 (15%) Query: 49 SESGRVFPVYNPATGEQVC--EVQEADKADIDKAVQAARLAF-----SLGSVWRRMDASE 101 S G+ F + PA+GE V DI ++ A + WR S Sbjct: 60 SHLGKTFELDQPASGETVGAERSPYGVALDIRYP-KSTPDALIAAAAAAQRTWREAGPSA 118 Query: 102 RGRLLDKLADLVERDRAVLAT----------MESLNGGKPFLQAFYVD-LQGVIKTFRYY 150 + ++ + R +A M + G P Q ++ + R Sbjct: 119 WIGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDQLRRI 178 Query: 151 AGWA--DKIHGMTIPVDGDYFTFTRHEPIGVCGQ---IIPWN-FPLLMFAWKIAPALCCG 204 A +K G P+ G+ WN +P L L G Sbjct: 179 PADAHWEKPQGKNPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGLFA------DLATG 232 Query: 205 NTVVIKPAEQTPLSALYMGAL----IKEAGFPPGVINIL---PGYGPTAGAAIASHIGID 257 NTV++KP L + ++EAGF P V+ +L P G +A I Sbjct: 233 NTVIVKPHPGAILPLAITVRIARDVLREAGFDPNVVTLLATEPNDGALV-QDLALRPEIK 291 Query: 258 KIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQG 317 I FTGST+ G ++ A ++ +V E G + +I + DL A + + G Sbjct: 292 LIDFTGSTQNGTWLERHAHQA---QVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSG 348 Query: 318 QCCTAGSRIFVEE---------SIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQY 368 Q CTA I+V + ++E + ++ G P G Q Sbjct: 349 QMCTAPQNIYVPRDGIRTADGHASFDEVAQAIAGAVQKLT-GDPARSVELIGAI----QN 403 Query: 369 NKILELIQSGVAEGAKLECGGKGLGRKGF----FIEPTVFSNVTDDMRIAKEEIFGPVQE 424 + + I + A G ++ + L F P V D +E FGP+ Sbjct: 404 DGVTARIDAARAVG-RVLLDSQTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISF 462 Query: 425 ILRFKTMDEVIERANN--SDFG-LVAAVFT--ND-INKALTVSSAMQA-------GTVWI 471 ++ + + ++ A ++ G L +V++ +D I+ A + G V++ Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 472 NCYNALN 478 N A + Sbjct: 523 NQSAAFS 529 >3K9D-A nrPDB Length = 464 Score = 151 bits (382), Expect = 7e-37, Method: Composition-based stats. Identities = 76/433 (17%), Positives = 130/433 (30%), Gaps = 47/433 (10%) Query: 73 DKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPF 132 ++ +++A A M + ++ +AD R LA M G Sbjct: 10 SIQEVRNLIESANKA---QKELAAMSQQQIDTIVKAIADAGYGAREKLAKMAHEETGFGI 66 Query: 133 LQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLM 192 Q ++ V + Y D + D + P+GV +IP P Sbjct: 67 WQ--DKVIKNVFASKHVYNYIKDMKTIGMLKEDNEKKVMEVAVPLGVVAGLIPSTNPTST 124 Query: 193 FAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA----GFPPGVINILPGYGPTAGA 248 +K ++ GN++V P + L +I EA G P G I+ + Sbjct: 125 VIYKTLISIKAGNSIVFSPHPNALKAILETVRIISEAAEKAGCPKGAISCMTVPTIQGTD 184 Query: 249 AIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQA 308 + H I TG + A S+ G P I A++ AV+ Sbjct: 185 QLMKHKDTAVILATGGSA-----MVKAAYSSGTPAIGVGPGNGPAFIERSANIPRAVKHI 239 Query: 309 HQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVER-------AKRRVVGS-PFDPTTEQG 360 F+ G C + + VE E + ++ A+ +G P Sbjct: 240 LDSKTFDNGTICASEQSVVVERVNKEAVIAEFRKQGAHFLSDAEAVQLGKFILRPNGSMN 299 Query: 361 PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG 420 P I K I L V A++ + + G I E Sbjct: 300 PAIVGKSVQHIANLAGLTVPADARVLIAEET--KVGAKIP-------------YSREKLA 344 Query: 421 PVQEILRFKTMDEVIERANNSDF----GLVAAVFTNDINKALTVSSAMQAGTVWINCYNA 476 P+ +T E E + + + G + + D + + +N A Sbjct: 345 PILAFYTAETWQEACELSMDILYHEGAGHTLIIHSEDKEIIREFALKKPVSRLLVNTPGA 404 Query: 477 LNAQSPFGGFKMS 489 L GG + Sbjct: 405 L------GGIGAT 411 >1O20-A nrPDB Length = 427 Score = 112 bits (280), Expect = 4e-25, Method: Composition-based stats. Identities = 85/467 (18%), Positives = 143/467 (30%), Gaps = 91/467 (19%) Query: 77 IDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKP----F 132 +D+ ++ A+ V R E+ + + K+A+ ++ R + ++ K Sbjct: 13 MDELLEKAKKVREAWDVLRNATTREKNKAIKKIAEKLDERRKEILEANRIDVEKARERGV 72 Query: 133 LQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTR---------HEPIGVCGQI 183 ++ L K + + G+ PV ++ R PIG G I Sbjct: 73 KESLVDRLALNDKRIDEMIKACETVIGLKDPVGEVIDSWVREDGLRIARVRVPIGPIGII 132 Query: 184 ---IPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA----GFPPGVI 236 P + AL GNT++++ S + + I+EA P + Sbjct: 133 YESRP-----NVTVETTILALKSGNTILLRGGSDALNSNKAIVSAIREALKETEIPESSV 187 Query: 237 NILPGYGPTAGAAIAS-HIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELG-GKSPNI 294 + + + + + G + R N LE G G Sbjct: 188 EFIENTDRSLVLEMIRLREYLSLV-----IPRGGYGLISFVRDNATVPVLETGVGNCHIF 242 Query: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFD 354 + ADL AV G C A ++ V E I +EF+ Sbjct: 243 VDESADLKKAVPVIINAKTQRPG-TCNAAEKLLVHEKIAKEFL----------------- 284 Query: 355 PTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIA 414 P I ++ G ++ K I P V DD Sbjct: 285 ------PVI-----------VEELRKHGVEV-----RGCEKTREIVPDVVPATEDD---W 319 Query: 415 KEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCY 474 E + I K +DE IE G ++ T + + A S + A V++N Sbjct: 320 PTEYLDLIIAIKVVKNVDEAIEHIKKYSTGHSESILTENYSNAKKFVSEIDAAAVYVNAS 379 Query: 475 NALNAQSPFGGFKMSGNGREM----------GEFGLREYSEVKTVTV 511 F G G E+ G GLRE + K V + Sbjct: 380 TRFTDGGQF------GFGAEIGISTQRFHARGPVGLRELTTYKFVVL 420 >4GHK-A nrPDB Length = 444 Score = 99 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 74/433 (17%), Positives = 123/433 (28%), Gaps = 72/433 (16%) Query: 104 RLLDKLADLVERDRAVLATMESLNGG----KPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 L+ +A +ERD L + + K AF L K + ++ Sbjct: 52 AALEAVARAIERDAGALKAANARDVARAKDKGLDAAFVDRLTLSDKALKTMVEGLRQVAT 111 Query: 160 MTIPV---------DGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK 210 + P+ P+GV G I + A L GN +++ Sbjct: 112 LPDPIGEMSNLKYRPSGIQVGQMRVPLGVIGIIYESR--PNVTIDAAALCLKSGNATILR 169 Query: 211 PAEQTPLSALYMGALI----KEAGFPPGVINIL-PGYGPTAGAAIASHIGIDKIAFTGST 265 + S + LI EAG P + ++ G I +D I Sbjct: 170 GGSEALESNTALAKLIGEGLAEAGLPQDTVQVVETADRAAVGRLITMTEYVDVIV----P 225 Query: 266 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 325 GK + E + L G + A + A+ G C Sbjct: 226 RGGKSLIERLINEARVPMIKHLDGICHVYVDDRASVTKALTVCDNAKTHRYG-TCNTMET 284 Query: 326 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 385 + V I + G +K ++ V E A Sbjct: 285 LLVARGIAPAVLSPL-------------------GRLYREKGVELRVDADARAVLEAAG- 324 Query: 386 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFG- 444 + P + TD+ + E PV I +D IE N ++G Sbjct: 325 -------------VGP--LVDATDED--WRTEYLAPVLAIKIVDGIDAAIEHIN--EYGS 365 Query: 445 -LVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFG-----GFKMSGNGREMGEF 498 A+ T D ++A+ + + +V +N FG G G Sbjct: 366 HHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHAR-GPV 424 Query: 499 GLREYSEVKTVTV 511 GL + +K V + Sbjct: 425 GLEGLTSLKYVVL 437 >1VLU-A nrPDB Length = 468 Score = 81.4 bits (200), Expect = 9e-16, Method: Composition-based stats. Identities = 67/447 (14%), Positives = 133/447 (29%), Gaps = 83/447 (18%) Query: 82 QAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATM------ESLNGG------ 129 Q A+ A G++ + + R +L K+ D ++ + + + G Sbjct: 18 QIAKNARKAGNILKTISNEGRSDILYKIHDALKANAHAIEEANKIDLAVAKETGLADSLL 77 Query: 130 KPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIP--VDGDYFTFTRHEPIGVCGQIIPWN 187 K + +++ + A D + + + +D + P+GV I + Sbjct: 78 KRLDLFKGDKFEVMLQGIKDVAELEDPVGKVKMARELDDGLTLYQVTAPVGVLLVI--FE 135 Query: 188 FPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK--------EAGFPPGVINIL 239 + A A ++ GN ++K +++ + M ++ E G P G + ++ Sbjct: 136 SRPEVIANITALSIKSGNAAILKGGKESVNTFREMAKIVNDTIAQFQSETGVPVGSVQLI 195 Query: 240 PGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADA 299 + ID + GS + + I++ + V G + DA Sbjct: 196 E-TRQDVSDLLDQDEYIDLVVPRGSNALVRKIKD----TTKIPVLGHADGICSIYLDEDA 250 Query: 300 DLDYAVEQAHQGVFFN-QGQCCTAGSRIFVEE--SIYEEFVRRS-------VERAKRRVV 349 DL A + G C A + + S + E + + K Sbjct: 251 DLIKAKRISLDAKTNYPAG--CNAMETLLINPKFSKWWEVLENLTLEGGVTIHATKDLKT 308 Query: 350 GSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTD 409 FD E G + Q TV ++ Sbjct: 309 AY-FDKLNELGKLTEAIQCK--------------------------------TVDADEEQ 335 Query: 410 DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTV 469 D +E + + I+ N A+ T + A + + V Sbjct: 336 D---FDKEFLSLDLAAKFVTSTESAIQHINTHSSRHTDAIVTENKANAEKFMKGVDSSGV 392 Query: 470 WINCYNALNAQSPFGGFKMSGNGREMG 496 + N GF+ G G E+G Sbjct: 393 YWNASTRFAD-----GFRY-GFGAEVG 413 >4JBE-A nrPDB Length = 445 Score = 77.6 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 74/444 (16%), Positives = 129/444 (29%), Gaps = 77/444 (17%) Query: 70 QEADKADIDKAVQA-ARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNG 128 A ++ KAV+ AR A S + L+ +AD + R + + + Sbjct: 30 SNAMTNEVAKAVEECARAAKSAAPSLSGAPDTAIDAALESMADRLLAHRDAVLAANAEDI 89 Query: 129 GKP-----------FLQAFYVDLQGVIKTFRYYAGWA-DKIHGMTIPVDGDYFTFTRHEP 176 K L L + R AG + +DG R P Sbjct: 90 AKAEAGGMSAGLLDRLTITESRLTDMADQLRLLAGAPHPQRTVELSTLDGGLRLVERRRP 149 Query: 177 IGVCGQIIPWNFPL--LMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGAL-----IKEA 229 +GV G N+ + + + N V++ SA + + + ++ Sbjct: 150 VGVIGA----NYEARPNVTVDVASQLVKSRNAGVLRTGSAALKSAQRLLEVVIRPALTDS 205 Query: 230 GFPPGVINILPGYGPTAGAAIASHIG-IDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELG 288 G V+ ++P A A+ + + GS E + + A + ++ + G Sbjct: 206 GIDANVVQLVPRPEREAAGALVRLPDLVPLVILRGSGESTRALALEAAQHGVRTLAHADG 265 Query: 289 GKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRV 348 G + AD D + C + + + +++YEEF E R Sbjct: 266 G-GVLYVDEKADRDTVRSLVVNSLDRLG--VCNRLNLLLIHDAVYEEFWPVVSEALAERG 322 Query: 349 VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVT 408 V + P Y L+ + A++ V Sbjct: 323 V------SPSLPPYDHPIGYEWALDSEREATVTVARV-------------------DGVA 357 Query: 409 DDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGT 468 + +RIA EE GL A + T D A Q Sbjct: 358 EAVRIANEET------------------------SGLAAGIATEDARAAEEFFDGYQGTG 393 Query: 469 VWINCYNALNAQSPFGGFKMSGNG 492 V+ N L G +G Sbjct: 394 VFWNAPTRLLDGFKLLGVPETGIN 417 >2H5G-A nrPDB Length = 463 Score = 73.0 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 71/460 (15%), Positives = 127/460 (27%), Gaps = 101/460 (21%) Query: 87 AFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFY--------- 137 A S G + ++ +R ++ LADL+ R + K +A Sbjct: 38 ARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLA----NKKDLEEAEGRLAAPLLKR 93 Query: 138 -----VDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHE---PIGVCGQIIPWNF- 188 L + R A + G + + PIGV I F Sbjct: 94 LSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVI----FE 149 Query: 189 --PLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEA----GFPPGVINILPGY 242 P + A A+ GN +++K ++ S + L +EA G + ++ Sbjct: 150 SRPDCLP-QVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGV-KEAVQLVN-T 206 Query: 243 GPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLD 302 ID I GS+++ + IQ+AA V G + ++A +D Sbjct: 207 REEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAA---KGIPVMGHSEGICHMYVDSEASVD 263 Query: 303 YAVEQAHQGVFFNQGQCCTAGSRIFVEES-----IYEEFVRRSVERAKRRVVGSPFDPTT 357 C A + + ++++ + R ++ + Sbjct: 264 KVTRLVRDSKCEYPA-ACNALETLLIHRDLLRTPLFDQIIDML--RVEQVKI-------- 312 Query: 358 EQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEE 417 GP K + +E L L Sbjct: 313 HAGP--------KFASYLTFSPSEVKSLRTEYGDLE------------------------ 340 Query: 418 IFGPVQEILRFKTMDEVIERANNSDFG--LVAAVFTNDINKALTVSSAMQAGTVWINCYN 475 I + + I+ +G + T D N A + + V+ N Sbjct: 341 -----LCIEVVDNVQDAIDHI--HKYGSSHTDVIVTEDENTAEFFLQHVDSACVFWNAST 393 Query: 476 ALNAQSPFG-----GFKMSGNGREMGEFGLREYSEVKTVT 510 + FG G S G GL K + Sbjct: 394 RFSDGYRFGLGAEVGISTSRIHAR-GPVGLEGLLTTKWLL 432 >3AGK-A nrPDB Length = 373 Score = 33.7 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 34/101 (33%), Gaps = 23/101 (22%) Query: 334 EEFVRRSVERAKRRVVGS-PFDPTTEQGP----QIDKKQYNKILELIQSGVAEGAKLECG 388 EEF + V G + E G I + + E ++ + GA++ Sbjct: 287 EEFKLHLAKGTGMIVYGEKDVEAALEMGAVKTLLIHE-SREDLEEWVEKAKSSGAQVIVV 345 Query: 389 GKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFK 429 + L +F++ FG + ILRF+ Sbjct: 346 PESLAEAEWFLK-----------------TFGGLAGILRFR 369 >3DOD-A nrPDB Length = 448 Score = 32.1 bits (72), Expect = 0.58, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 29/89 (32%), Gaps = 8/89 (8%) Query: 49 SESGRVFPVYNPATGEQVCEVQEADKADIDKA-----VQAARLAFSLGSVWRRMDASE-R 102 E + + N G+ + V ++ + D E R Sbjct: 134 PEKQKFIAMKNGYHGDTIGAVSVGSIELFHHVYGPLMFESYKAPIPYVYRSESGDPDECR 193 Query: 103 GRLLDKLADLVERDRAVLATM--ESLNGG 129 + L +LA L+E +A + ES+ G Sbjct: 194 DQCLRELAQLLEEHHEEIAALSIESMVQG 222 >5UPP-A nrPDB Length = 466 Score = 31.4 bits (70), Expect = 0.93, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 60/186 (32%), Gaps = 20/186 (10%) Query: 221 YMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGS-TEVGKLIQEAAGRSN 279 + ++ G P + N + + + TGS T+ + E Sbjct: 58 AAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRA 117 Query: 280 LKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEE-------SI 332 ++ + ELG K P + + ++ Q+ F A V E + Sbjct: 118 IEMLGGELGSKIP--VHPNDHVNK--SQSSNDTFPTAMHIAAAIE---VHEVLLPGLQKL 170 Query: 333 YEEFVRRSVERAKRRVVGSPFDPTT---EQGPQIDK--KQYNKILELIQSGVAEGAKLEC 387 ++ +S E A+ +G G + +Q + I++ + +L Sbjct: 171 HDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAA 230 Query: 388 GGKGLG 393 GG +G Sbjct: 231 GGTAVG 236 >3Q09-A nrPDB Length = 248 Score = 31.4 bits (70), Expect = 0.96, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 16/31 (51%) Query: 88 FSLGSVWRRMDASERGRLLDKLADLVERDRA 118 F L W ++ +ER +++ L+E+ + Sbjct: 27 FKLRPDWNKVPVAERKGAAEEVKKLIEKHKD 57 >4Q1V-A nrPDB Length = 710 Score = 31.0 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 21/59 (35%), Gaps = 4/59 (6%) Query: 451 TNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFK---MSGNGREMGEFGLREYSEV 506 T T +++G +N N +Q PF K SG G + + YS Sbjct: 367 TKRKEVIFTAVEGLRSGHFAVNVSNGKISQ-PFENCKESEHSGTLSASGTYLIDRYSTK 424 >6AHD-9 nrPDB Length = 800 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 29/78 (37%), Gaps = 14/78 (17%) Query: 60 PATGEQVCEVQEADKADIDKAVQAARLAFSLGS------------VWRRMDAS--ERGRL 105 P T + + + + ++ + + AA+ L W A+ ER R Sbjct: 150 PVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQ 209 Query: 106 LDKLADLVERDRAVLATM 123 L K DL E+ +L M Sbjct: 210 LQKEKDLAEKRAKLLEEM 227 >4G9Q-A nrPDB Length = 269 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 29/72 (40%), Gaps = 10/72 (13%) Query: 90 LGSVWRRMDASERGRLLDKLADLV---ERDRAVLATMESLNGG-KPFLQAFYVDLQGVIK 145 G VW+R + R R L +A L+ E ++L G KP ++ I Sbjct: 62 YGDVWQRPGLNRRDRSLVTIAALIARGEAPALTYYADQALENGVKP------SEISETIT 115 Query: 146 TFRYYAGWADKI 157 YY+GW + Sbjct: 116 HLAYYSGWGKAM 127 >4U83-A nrPDB Length = 382 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 31/93 (33%), Gaps = 10/93 (10%) Query: 77 IDKAVQAARLAFSLGSVWRR------MDASERGRLLDKLADLVER----DRAVLATMESL 126 +AV AR AF + R E + +LAD+ R + VL Sbjct: 252 AAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAAALR 311 Query: 127 NGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHG 159 GKP L + + A +IHG Sbjct: 312 EAGKPCLTEASMAKLVASEMAEQVCSAAIQIHG 344 >4N4Q-A nrPDB Length = 296 Score = 30.6 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 29/83 (34%), Gaps = 23/83 (27%) Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-- 268 PA TP + + +AG V+N + +D I TGST Sbjct: 12 PAMVTPFTKDG---KLHKAGV-KEVVNF-----------LVEKQKVDGIYITGSTGEFLL 56 Query: 269 ------KLIQEAAGRSNLKRVTL 285 K + + +N RVTL Sbjct: 57 LSFEDKKEVMKLVAEANAGRVTL 79 >1NNE-A nrPDB Length = 765 Score = 30.2 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 5/81 (6%) Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI-- 157 E+ R + +L L+ R R +E K +A + ++ YA A+ Sbjct: 482 KEKEREVYRLEALIRR-REEEVFLEVRERAKRQAEALR-EAARILAELDVYAALAEVAVR 539 Query: 158 HGMTIPVDGDYFTFT-RHEPI 177 +G P GD P+ Sbjct: 540 YGYVRPRFGDRLQIRAGRHPV 560 >5WYK-3D nrPDB Length = 504 Score = 30.2 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 405 SNVTDDMRIAKEEI--FGP------VQEILRFKTMDEVIERANNSDFGLVA----AVFTN 452 ++ ++ +E+I FG + FK E +E AN+ GLV+ A+ Sbjct: 25 DDIGSRLKEVQEQINDFGAFTKLIELVSFAPFKGAAEALENANDISEGLVSESLKAILDL 84 Query: 453 DINKALTVSSAMQAGTVWINCYNALNAQSPF 483 ++ KA + + N ++ + P+ Sbjct: 85 NLPKASSKKKNITLAISDKNLGPSIKEEFPY 115 >1EWR-A nrPDB Length = 649 Score = 30.2 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 5/81 (6%) Query: 100 SERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI-- 157 E+ R + +L L+ R R +E K +A + ++ YA A+ Sbjct: 366 KEKEREVYRLEALIRR-REEEVFLEVRERAKRQAEALR-EAARILAELDVYAALAEVAVR 423 Query: 158 HGMTIPVDGDYFTFT-RHEPI 177 +G P GD P+ Sbjct: 424 YGYVRPRFGDRLQIRAGRHPV 444 >3LOO-A nrPDB Length = 365 Score = 30.2 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 22/49 (44%), Gaps = 8/49 (16%) Query: 416 EEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAM 464 EEIF P ++L F E I A ++G T D+ + +A+ Sbjct: 226 EEIF-PYVDVL-FGNETEAIALAKEFNYG------TEDLREIGKRIAAL 266 >1V9N-A nrPDB Length = 360 Score = 29.8 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 43/93 (46%), Gaps = 14/93 (15%) Query: 405 SNVTDDMRIAKEEIFGP----------VQEILRFKTMDEVIERANNSDFGLVAAVFTNDI 454 N+ +R+ +E GP + +++ +++M I++A ++ G+V A +N Sbjct: 72 VNLHPKIRVIRE---GPSYALIDGDEGLGQVVGYRSMKLAIKKAKDTGIGIVIARNSNHY 128 Query: 455 NKALTVS-SAMQAGTVWINCYNALNAQSPFGGF 486 A + A + G + I+ N+ +P GG Sbjct: 129 GIAGYYALMAAEEGMIGISMTNSRPLVAPTGGI 161 >4WJB-A nrPDB Length = 424 Score = 29.8 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 221 YMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNL 280 + AG GV + G T GA +++I + G+ VG AA ++ Sbjct: 145 RFAPAMVSAGVFSGVYTLEYGLSRTDGAGRTIGEELERIGYAGAEPVGGYPVHAAYELHI 204 Query: 281 KR-VTLELGGK 290 ++ LE GK Sbjct: 205 EQGAILERAGK 215 >2CUN-A nrPDB Length = 410 Score = 29.8 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 5/66 (7%) Query: 360 GPQIDKKQYNKILELIQSGVAEGAKLECG---GKGLGRKGFFIEPT--VFSNVTDDMRIA 414 G I ++ +L I+ + GAK+ G GK E V S + D Sbjct: 27 GKIISDARFKAVLPTIRYLIESGAKVVIGTHQGKPYSEDYTTTEEHARVLSELLDQHVEY 86 Query: 415 KEEIFG 420 E+IFG Sbjct: 87 IEDIFG 92 >3UF0-A nrPDB Length = 273 Score = 29.4 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 27/79 (34%), Gaps = 13/79 (16%) Query: 233 PGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLE---LGG 289 G ++ G G G AIA G G + +K V E GG Sbjct: 30 AGRTAVVTGAGSGIGRAIAH----------GYARAGAHVLAWGRTDGVKEVADEIADGGG 79 Query: 290 KSPNIIFADADLDYAVEQA 308 + ++ ADL+ A A Sbjct: 80 SAEAVVADLADLEGAANVA 98 >6D6K-A nrPDB Length = 705 Score = 29.1 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 30/184 (16%), Positives = 60/184 (32%), Gaps = 35/184 (19%) Query: 1 MTSSKIEMPGEVKADPAALM---ASLHLLPSPTPNLEIKYTKIFINNEWQ-----NSESG 52 +T++ + ++AD AA++ A+L + +P IN E+ + Sbjct: 122 VTATVVSSDKTMEADIAAMLGTSAALAIAGTPFRGPIGAARVGLINGEYVLNPNFEQMAQ 181 Query: 53 RVFPVYNPATGEQVCEVQEADKA---------------DIDKAVQA----ARLAFSLGSV 93 + T V V+ K ++ A+QA A A + S Sbjct: 182 SDLDLVVAGTESAVLMVESEAKELSEDQMLGAVLFGHDEMQIAIQAINEFAAAAGAKPSD 241 Query: 94 WRRMDASE--RGRLLDKLADLVER------DRAVLATMESLNGGKPFLQAFYVDLQGVIK 145 W +E R +L + + + A +++L+ D+ G+ Sbjct: 242 WVAPAHNEELRAKLKEAFEAKISEAYTIAVKQDRYAALDALHAEAVAQFVPEEDVDGIAD 301 Query: 146 TFRY 149 Y Sbjct: 302 EVDY 305 >1J3N-A nrPDB Length = 408 Score = 29.1 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 37/105 (35%), Gaps = 13/105 (12%) Query: 211 PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPT--AGA---------AIASHIGIDKI 259 P + +AL M +K+AG P + + +G + G H + Sbjct: 270 PHPEGKGAALAMARALKDAGIAPEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMV 329 Query: 260 AFTGSTEVGKLIQEAAGRSNLKRV-TLELGGKSPNIIFADADLDY 303 + T S +G L+ A + V L G P I D D + Sbjct: 330 SSTKSM-IGHLLGAAGAVEAIATVQALYHGVIPPTINLEDPDPEL 373 >3HOA-A nrPDB Length = 509 Score = 29.1 bits (64), Expect = 5.5, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 26/76 (34%), Gaps = 2/76 (2%) Query: 84 ARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAV--LATMESLNGGKPFLQAFYVDLQ 141 A A+ ++ + R R + LA L+ + + G P +Q D Sbjct: 25 ALAAWDQRTMIPKKGHEHRARQMAALARLLHQRMTDPRIGEWLEKVEGSPLVQDPLSDAA 84 Query: 142 GVIKTFRYYAGWADKI 157 ++ +R A I Sbjct: 85 VNVREWRQAYERARAI 100 >3C3E-A nrPDB Length = 311 Score = 28.7 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 329 EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILE 373 E SI + + E+ + ++G P +P T GP I ++L+ Sbjct: 170 EASISPKVLEAF-EKEENILIG-PSNPITSIGPIISLPGMRELLK 212 >4WHB-E nrPDB Length = 461 Score = 28.7 bits (63), Expect = 6.6, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 6/69 (8%) Query: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389 E Y E + + + A R V + FD P + + + I +G+++GA++ G Sbjct: 88 EGRYVEVIEEAAQLALRNGVTTVFDTHNAIEPVLAAR------DRINAGISQGARIFAAG 141 Query: 390 KGLGRKGFF 398 +G G F Sbjct: 142 TIVGMGGPF 150 >3HSK-A nrPDB Length = 381 Score = 28.3 bits (62), Expect = 8.6, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 19/57 (33%) Query: 328 VEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAK 384 V I + FV + P ++ + + + ++ V++G K Sbjct: 105 VAGDIEKSFVEAGLAVVSNAKNYRREKDVPLVVPIVNPEHIDVVENKVKQAVSKGGK 161 >4G09-A nrPDB Length = 438 Score = 28.3 bits (62), Expect = 8.8, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 29/84 (34%), Gaps = 17/84 (20%) Query: 411 MRIAKEEI-------FGPVQEILRFKTMDEVIERANNSDF-GLVAAVFTNDINKALTVSS 462 +A+ E FG ++ K ++ I AN L AV A Sbjct: 290 HTLARTETASASWRDFG---AVILVKDFEDAIPLANRIAAEHLEIAV-----ADAEAFVP 341 Query: 463 AMQ-AGTVWINCYNALNAQSPFGG 485 ++ AG+++I Y GG Sbjct: 342 RIRNAGSIFIGGYTPEVIGDYVGG 365 >3A2Q-A nrPDB Length = 493 Score = 28.3 bits (62), Expect = 9.4, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 19/57 (33%), Gaps = 8/57 (14%) Query: 108 KLADLVERDRAVLATMESL--------NGGKPFLQAFYVDLQGVIKTFRYYAGWADK 156 +A +ER+ ++ + K Q + RYYAG ++ Sbjct: 319 AIAREIERNGELIGRPLTEDDVEWTSWEMVKRADQVTGRAFAACVDELRYYAGKVER 375 >2IPH-A nrPDB Length = 181 Score = 27.9 bits (61), Expect = 9.9, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 396 GFFIEPTVFSNVTDDMRIAKEEIFG-PVQEI 425 GF++ PTVF T + + +E FG P+ I Sbjct: 17 GFWVSPTVFITTTHVIPTSAKEFFGEPLTSI 47 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.155 0.451 Lambda K H 0.267 0.0474 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,755,372 Number of Sequences: 36641 Number of extensions: 1067417 Number of successful extensions: 4523 Number of sequences better than 10.0: 148 Number of HSP's better than 10.0 without gapping: 215 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 3377 Number of HSP's gapped (non-prelim): 284 length of query: 518 length of database: 10,336,785 effective HSP length: 101 effective length of query: 417 effective length of database: 6,636,044 effective search space: 2767230348 effective search space used: 2767230348 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 62 (28.3 bits)