BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O81862 (379 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3AQU-A nrPDB 726 0.0 3ALF-A nrPDB 424 e-119 4URI-A nrPDB 337 4e-93 4MNK-A nrPDB 295 2e-80 4WKA-A nrPDB 201 5e-52 1WB0-A nrPDB 199 2e-51 5WUS-A nrPDB 187 9e-48 5WV8-A nrPDB 182 2e-46 3RM8-A nrPDB 166 1e-41 4P8U-A nrPDB 160 8e-40 1E9L-A nrPDB 157 6e-39 1HJW-A nrPDB 154 4e-38 2QF8-A nrPDB 149 2e-36 5XEP-A nrPDB 142 2e-34 6G9C-A nrPDB 140 7e-34 5GZU-A nrPDB 138 5e-33 5Y29-A nrPDB 136 2e-32 6BT9-A nrPDB 135 3e-32 3WD0-A nrPDB 132 2e-31 1ITX-A nrPDB 130 6e-31 6EPB-A nrPDB 129 2e-30 3W4R-A nrPDB 127 7e-30 3WKZ-A nrPDB 127 1e-29 3G6L-A nrPDB 117 6e-27 1LL6-A nrPDB 115 4e-26 5Y2C-A nrPDB 114 6e-26 3CHF-A nrPDB 107 1e-23 3ARQ-A nrPDB 96 3e-20 5GQB-A nrPDB 95 5e-20 3QOK-A nrPDB 90 1e-18 5ZL9-A nrPDB 87 9e-18 5DF0-A nrPDB 85 6e-17 1KFW-A nrPDB 82 4e-16 6F8N-A nrPDB 82 5e-16 4TXG-A nrPDB 81 8e-16 5Z7M-A nrPDB 80 2e-15 5XWF-A nrPDB 79 3e-15 4W5U-B nrPDB 77 1e-14 6OGD-C nrPDB 77 2e-14 4DWS-C nrPDB 76 2e-14 1JNE-A nrPDB 70 1e-12 4A5Q-A nrPDB 57 2e-08 3CZ8-A nrPDB 51 8e-07 4Q6T-A nrPDB 47 2e-05 3CO4-A nrPDB 45 4e-05 4S3J-A nrPDB 43 2e-04 4WIW-A nrPDB 42 5e-04 4S3K-A nrPDB 42 5e-04 3IAN-A nrPDB 37 0.010 5JH8-A nrPDB 37 0.011 4TX8-A nrPDB 37 0.012 4AXN-A nrPDB 37 0.015 3EBV-A nrPDB 32 0.33 1MW7-A nrPDB 32 0.65 3SIM-A nrPDB 30 1.7 4EPS-A nrPDB 28 5.3 >3AQU-A nrPDB Length = 356 Score = 726 bits (1875), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/355 (100%), Positives = 355/355 (100%) Query: 25 QTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ 84 QTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ Sbjct: 2 QTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ 61 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 144 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS Sbjct: 62 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 121 Query: 145 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN 204 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN Sbjct: 122 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN 181 Query: 205 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR 264 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR Sbjct: 182 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR 241 Query: 265 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 324 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY Sbjct: 242 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 301 Query: 325 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV 379 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV Sbjct: 302 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV 356 >3ALF-A nrPDB Length = 353 Score = 424 bits (1091), Expect = e-119, Method: Compositional matrix adjust. Identities = 210/343 (61%), Positives = 244/343 (71%), Gaps = 5/343 (1%) Query: 28 VKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRN 87 VK YWF S + +IDS+LFTHLFCAFADLN Q NQ+ +S NQ F FT TVQR+N Sbjct: 4 VKGGYWFKDSGLALNNIDSTLFTHLFCAFADLNPQLNQLIISPENQDSFRQFTSTVQRKN 63 Query: 88 PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATE 147 PSVKT LSI GG A+ TAY MA P SRKSFIDSSIR+AR GFHGLDLDWEYP SA + Sbjct: 64 PSVKTFLSIAGGRANSTAYGIMARQPNSRKSFIDSSIRLARQLGFHGLDLDWEYPLSAAD 123 Query: 148 MTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMA 207 MTN GTLL EWR+A+ EA +SG+ LLL AAV S + YPV ++A +LDW+NLMA Sbjct: 124 MTNLGTLLNEWRTAINTEARNSGRAALLLTAAVSNSPRVNGLNYPVESLARNLDWINLMA 183 Query: 208 YDFYGPGWS-RVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLT 266 YDFYGP WS T A LFDP N SG G +WIQAG+P KK VLG P+YGYAWRL Sbjct: 184 YDFYGPNWSPSQTNSHAQLFDPVNH-VSGSDGINAWIQAGVPTKKLVLGIPFYGYAWRLV 242 Query: 267 NANSHSYYAPTTGAA---ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIG 323 NAN H AP G + DGS+ Y +IR +IV++ ATTVYN+T+VGDYCY+G+NWI Sbjct: 243 NANIHGLRAPAAGKSNVGAVDDGSMTYNRIRDYIVESRATTVYNATIVGDYCYSGSNWIS 302 Query: 324 YDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 YDD Q++ KV Y K RGLLGYF+WHV D N GLSR ASQ W Sbjct: 303 YDDTQTVRNKVNYVKGRGLLGYFAWHVAGDQNWGLSRTASQTW 345 >4URI-A nrPDB Length = 337 Score = 337 bits (865), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 181/344 (52%), Positives = 231/344 (67%), Gaps = 15/344 (4%) Query: 28 VKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRN 87 +K YW+ S V+DI+ S FTHLFCAFADL+ TN++T+SS+N FSTFTQTV+ +N Sbjct: 2 IKGGYWYSGSGLAVSDINPSHFTHLFCAFADLDPNTNKLTISSSNAAAFSTFTQTVRAKN 61 Query: 88 PSVKTLLSIGGGIADKTA--YASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSA 145 PSVKTLLSIGGG A +A+MAS + RKSFIDSSI++AR FHGLDLDWEYPSS Sbjct: 62 PSVKTLLSIGGGGGRALAAVFANMASQASRRKSFIDSSIQLARRNNFHGLDLDWEYPSSD 121 Query: 146 TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSV-LYPVSAVASSLDWVN 204 + TNF +L+REWR+AV E+S+SG P LLL+AAV S+ + YP A+A++LDWVN Sbjct: 122 IDKTNFASLIREWRAAVATESSTSGTPALLLSAAVGGSDQITPLKYYPGEAIANNLDWVN 181 Query: 205 LMAYDFY-GPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAW 263 +M YD Y + +T PPA LF P S D G WIQ+G+P K LG P+YG+ W Sbjct: 182 VMTYDLYTSDSYPTLTQPPAPLFYPRGIF-SADEGITKWIQSGVPESKLALGLPFYGFKW 240 Query: 264 RLTNANSHSYYAPTTGAAISPDGSIGYGQIR-KFIVDNGATTVYNSTVVGDYCYAGTNWI 322 RL++ N+H +AP T G G ++ K IV+ G ++ST V +Y + GT+W Sbjct: 241 RLSDPNNHGLFAPATQ---------GLGAVKYKDIVNTGGQVEFDSTYVTNYRFKGTDWY 291 Query: 323 GYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 GYDD QSI KV YAKQRGL GYF+WH+ D N LS AS+AW Sbjct: 292 GYDDTQSISAKVAYAKQRGLFGYFAWHIEQDSNWALSETASRAW 335 >4MNK-A nrPDB Length = 348 Score = 295 bits (756), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 157/349 (44%), Positives = 218/349 (62%), Gaps = 11/349 (3%) Query: 25 QTVVKASYW--FPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQT 82 Q +K +W + SEFP + I+S LFTHL+ AFA+LN+ T +V V ++ FT T Sbjct: 2 QNALKVGFWPAYSVSEFPPSKINSRLFTHLYYAFAELNAPTFEVRVPPGSEKTAEDFTPT 61 Query: 83 VQRRNPSVKTLLSIGGGIAD-KTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEY 141 V+R NPSVKTL+SIGGG ++ + +A + S+ ++R+ F+ SSI +AR YGFHGLDLD+EY Sbjct: 62 VRRLNPSVKTLISIGGGGSEVRDNFAKLNSDASARQRFVKSSIALARRYGFHGLDLDYEY 121 Query: 142 PSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYS----VLYPVSAVA 197 P EM NF L+ E +A+ EA +SGKPRLLL AV++ + YPV +A Sbjct: 122 PEPQLEMENFVKLVSELTAAIREEARTSGKPRLLLTEAVYFHQKLFPWEVVTEYPVQFIA 181 Query: 198 SSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFP 257 + LDWVN+MAYDF+G W TG PAAL DP N+ + G S++ AG+P +K VLG P Sbjct: 182 AGLDWVNVMAYDFHG-SWENFTGAPAALRDP-NSKFTASVGIESFLAAGMPPEKLVLGIP 239 Query: 258 YYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYA 317 +G +W L N N AP GA DG++ + +I+ FI GA V+++T V Y Y Sbjct: 240 LFGRSWLLKNNNEVGIGAPAVGAG-PVDGALSFSEIQNFI-RGGAREVFDTTTVSAYAYK 297 Query: 318 GTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 W+GYD+ QS+ KV+YAK++ L GYF W V D ++ L + AS W Sbjct: 298 DNVWVGYDNQQSVALKVQYAKEKRLGGYFFWSVNQDIDAILPKIASDTW 346 >4WKA-A nrPDB Length = 377 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 126/344 (36%), Positives = 182/344 (52%), Gaps = 20/344 (5%) Query: 30 ASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPS 89 A Y + F D+D SL THL AFA + + +Q++ + N +++ NP Sbjct: 11 AQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN--HQLSTTEWNDETLYQEFNGLKKMNPK 68 Query: 90 VKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----A 145 +KTLL+IGG + M + +R++F++S+IR R Y F GLDLDWEYP S A Sbjct: 69 LKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA 128 Query: 146 TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNL 205 + F TL+++ +A EA +SGK RLLL+AAV Y Y V +A +LD+VNL Sbjct: 129 VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNL 188 Query: 206 MAYDFYGPGWSRVTGPPAALF---DPSNAGPS--GDAGTRSWIQAGLPAKKAVLGFPYYG 260 MAYDF+G W +VTG + L+ + S A S DA + W+Q G PA K +LG P YG Sbjct: 189 MAYDFHG-SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYG 247 Query: 261 YAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYC 315 ++ L +++ AP TG+ G + Y ++ + GAT Y Sbjct: 248 RSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW---KGATKQRIQDQKVPYI 304 Query: 316 YAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 + W+G+DD +S TKV Y KQ+GL G W + DD +G S Sbjct: 305 FRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 348 >1WB0-A nrPDB Length = 445 Score = 199 bits (506), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 126/344 (36%), Positives = 182/344 (52%), Gaps = 20/344 (5%) Query: 30 ASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPS 89 A Y + F D+D SL THL AFA + + +Q++ + N +++ NP Sbjct: 11 AQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN--HQLSTTEWNDETLYQEFNGLKKMNPK 68 Query: 90 VKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----A 145 +KTLL+IGG + M + +R++F++S+IR R Y F GLDLDWEYP S A Sbjct: 69 LKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA 128 Query: 146 TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNL 205 + F TL+++ +A EA +SGK RLLL+AAV Y Y V +A +LD+VNL Sbjct: 129 VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNL 188 Query: 206 MAYDFYGPGWSRVTGPPAALF---DPSNAGPS--GDAGTRSWIQAGLPAKKAVLGFPYYG 260 MAYDF+G W +VTG + L+ + S A S DA + W+Q G PA K +LG P YG Sbjct: 189 MAYDFHG-SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYG 247 Query: 261 YAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYC 315 ++ L +++ AP TG+ G + Y ++ + GAT Y Sbjct: 248 RSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW---KGATKQRIQDQKVPYI 304 Query: 316 YAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 + W+G+DD +S TKV Y KQ+GL G W + DD +G S Sbjct: 305 FRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 348 >5WUS-A nrPDB Length = 460 Score = 187 bits (474), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 109/334 (32%), Positives = 172/334 (51%), Gaps = 17/334 (5%) Query: 36 ASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTV--QRRNPSVKTL 93 A F ++D +L TH+ AFA L ++ A++ + + V + +NP++K L Sbjct: 18 AGRFMPENVDPTLCTHVIYAFATLKDHK----LTEADEKDADMYDKVVALREKNPNLKIL 73 Query: 94 LSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGT 153 L+IGG T + + SN F+ +I R Y F+GLD+DWEYP A + F + Sbjct: 74 LAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYPRGADDRAAFVS 133 Query: 154 LLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGP 213 LL+E R A EA +SG+PRLLL AAV S + Y V ++ LD++N+M YDF+G Sbjct: 134 LLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHG- 192 Query: 214 GWSRVTGPPAALFDPSNAGP-----SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNA 268 W R G + LF +A + D R W++ G P +K ++G P YG ++ L N Sbjct: 193 QWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLIND 252 Query: 269 NSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIG 323 AP +G + G + Y +I +F+ ++ T V+++ + + Y W+G Sbjct: 253 TQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVG 312 Query: 324 YDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 357 +DD +S+ TK+ + K+ G G W V DD G Sbjct: 313 FDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRG 346 >5WV8-A nrPDB Length = 482 Score = 182 bits (463), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 116/336 (34%), Positives = 168/336 (50%), Gaps = 20/336 (5%) Query: 38 EFPVTDIDSSLFTHLFCAFADLNS------QTNQVTVSSANQPKFSTFTQTVQRRNPSVK 91 +F DI L TH+ AF L ++N T + +++ NP +K Sbjct: 111 KFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDET--KDGKTGLYDRINALKKANPKLK 168 Query: 92 TLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNF 151 TLL+IGG + M++ +R++FI S+I R F GLD+DW YP + N+ Sbjct: 169 TLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWLYPKGGDDKKNY 228 Query: 152 GTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFY 211 LL+E R A AEA KPRLLL AAV + Y V AVAS LD++NLMAYDF+ Sbjct: 229 VLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFH 288 Query: 212 GPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLT 266 G W R TG A L+ PS+ S D W++ G P +K ++G P YG + L+ Sbjct: 289 GK-WERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLS 347 Query: 267 NANSHSYYAPTTGAAISPD-----GSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNW 321 N N+ +P +G + + G + Y ++ + I+ NG V++ + Y G W Sbjct: 348 NPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCE-ILRNGGAYVWDDEMKVPYAIHGDQW 406 Query: 322 IGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 357 +G+DD +SI K+R+ K G W V DD SG Sbjct: 407 VGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSG 442 >3RM8-A nrPDB Length = 395 Score = 166 bits (421), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 110/333 (33%), Positives = 165/333 (49%), Gaps = 18/333 (5%) Query: 39 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGG 98 F DI+ L THL AFA + Q N++T N ++ +N +KTLL+IGG Sbjct: 20 FMPDDINPCLCTHLIYAFAGM--QNNEITTIEWNDVTLYQAFNGLKNKNSQLKTLLAIGG 77 Query: 99 GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----ATEMTNFGTL 154 + +M S P +R++FI S I+ R Y F GLD DWEYP S + F L Sbjct: 78 WNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQDKHLFTVL 137 Query: 155 LREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPG 214 ++E R A EA KPRL++ AAV + Y + ++ LD++++M YD +G Sbjct: 138 VQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHG-S 196 Query: 215 WSRVTGPPAALFD-PSNAGPSG----DAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNAN 269 W TG + L+ P++ G + D W G PA+K ++GFP YG+ + L+N + Sbjct: 197 WEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPS 256 Query: 270 SHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 324 + APT+GA G Y +I F+ NGAT +++ Y Y G W+GY Sbjct: 257 NTGIGAPTSGAGPAGPYAKESGIWAYYEICTFL-KNGATQGWDAPQEVPYAYQGNVWVGY 315 Query: 325 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 357 D+ +S K ++ K G W + DD +G Sbjct: 316 DNVKSFDIKAQWLKHNKFGGAMVWAIDLDDFTG 348 >4P8U-A nrPDB Length = 371 Score = 160 bits (405), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 107/334 (32%), Positives = 168/334 (50%), Gaps = 19/334 (5%) Query: 38 EFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIG 97 +F +ID L +HL +FA + + N+V + ++ +++ +NP +K LLSIG Sbjct: 26 KFTPENIDPFLCSHLIYSFASI--ENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIG 83 Query: 98 GGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLRE 157 G + + M + TSR FI+S I R++ F GLD+ W YP E T+F L+ E Sbjct: 84 GYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQK-ENTHFTVLIHE 142 Query: 158 WRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSR 217 A + + S K RLLL V Y V +A LD++NL+++DF+G W + Sbjct: 143 LAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHG-SWEK 201 Query: 218 --VTGPPAALFDP-SNAGPSG----DAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANS 270 +TG + L + GPS + WI G+P++K V+G P YG+++ L +A + Sbjct: 202 PLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAET 261 Query: 271 HSYYAPTTG-AAISP----DGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYD 325 + AP +G A P G + Y +I +F+ GA + Y G W+GYD Sbjct: 262 -TVGAPASGPGAAGPITESSGFLAYYEICQFL--KGAKITWLQDQQVPYAVKGNQWVGYD 318 Query: 326 DNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 D +S+ TKV++ K L G W + DD +G S Sbjct: 319 DVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKS 352 >1E9L-A nrPDB Length = 377 Score = 157 bits (398), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 105/333 (31%), Positives = 162/333 (48%), Gaps = 18/333 (5%) Query: 39 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGG 98 F +ID L THL AFA + Q N++T + + ++ +N +KTLL+IGG Sbjct: 20 FKPGNIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 77 Query: 99 GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----ATEMTNFGTL 154 +++M S P +R+ FI S IR R Y F GL+LDW+YP S + F L Sbjct: 78 WKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVL 137 Query: 155 LREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPG 214 ++E R A E+ PRLLL + + Y + ++ SLD++ +M YD + P Sbjct: 138 VKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPK 197 Query: 215 WSRVTGPPAALFD-PSNAGPSGDAGTRS----WIQAGLPAKKAVLGFPYYGYAWRLTNAN 269 TG + L+ P + G S D S W G ++K ++GFP YG+ + L++ + Sbjct: 198 -DGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPS 256 Query: 270 SHSYYAPTT-----GAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 324 APT G G + Y ++ F+ + GAT V+++ Y Y G W+GY Sbjct: 257 KTGIGAPTISTGPPGKYTDESGLLAYYEVCTFL-NEGATEVWDAPQEVPYAYQGNEWVGY 315 Query: 325 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 357 D+ +S K ++ K L G W + DD SG Sbjct: 316 DNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSG 348 >1HJW-A nrPDB Length = 362 Score = 154 bits (390), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 105/327 (32%), Positives = 170/327 (51%), Gaps = 24/327 (7%) Query: 44 IDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADK 103 +D L TH+ +FA++++ + + N T++ RNP++KTLLS+GG Sbjct: 25 LDRFLCTHIIYSFANISN--DHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGS 82 Query: 104 TAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVV 163 ++ +ASN SR++FI S R++GF GLDL W YP + +F TL++E ++ + Sbjct: 83 QRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGR-RDKQHFTTLIKEMKAEFI 141 Query: 164 AEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPA 223 EA GK +LLL+AA+ Y ++ ++ LD++++M YDF+G W TG + Sbjct: 142 KEA-QPGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHG-AWRGTTGHHS 199 Query: 224 ALFD-PSNAGP----SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTT 278 LF +A P + D ++ G PA K V+G P +G ++ L ++ + AP + Sbjct: 200 PLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSET-GVGAPIS 258 Query: 279 GAAI-----SPDGSIGYGQIRKFIVDNGATTVYNSTVVGD---YCYAGTNWIGYDDNQSI 330 G I G++ Y +I F+ GAT ++G Y G W+GYDD +S+ Sbjct: 259 GPGIPGRFTKEAGTLAYYEICDFL--RGATV---HRILGQQVPYATKGNQWVGYDDQESV 313 Query: 331 VTKVRYAKQRGLLGYFSWHVGADDNSG 357 +KV+Y K R L G W + DD G Sbjct: 314 KSKVQYLKDRQLAGAMVWALDLDDFQG 340 >2QF8-A nrPDB Length = 361 Score = 149 bits (377), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 106/345 (30%), Positives = 172/345 (49%), Gaps = 17/345 (4%) Query: 44 IDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADK 103 ID L TH+ +FA++++ N++ N T++ RNP++KTLLS+GG Sbjct: 25 IDPFLCTHVIYSFANISN--NEIDTWEWNDVTLYDTLNTLKNRNPNLKTLLSVGGWNYGS 82 Query: 104 TAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVV 163 ++ +AS SR++FI S R++GF GLDL W +P + + TL++E ++ V Sbjct: 83 QRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLWP-GWRDKRHLTTLVKEMKAEFV 141 Query: 164 AEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPA 223 EA +G +LLL+AAV Y ++ ++ LD+++L+ YDF+G W + G + Sbjct: 142 REA-QAGTEQLLLSAAVTAGKIAIDRGYDIAQISRHLDFISLLTYDFHG-AWRQTVGHHS 199 Query: 224 ALF----DPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTG 279 LF D S+ + D ++ G PA K V+G P +G ++ L ++ + AP +G Sbjct: 200 PLFRGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSYTLASSKT-DVGAPISG 258 Query: 280 AAISP-----DGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKV 334 I G + Y +I F+ +GATT Y G W+ YDD +S+ K Sbjct: 259 PGIPGRFTKWKGILAYYEICDFL--HGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKA 316 Query: 335 RYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV 379 RY K R L G W + DD G + + T+A + +V Sbjct: 317 RYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSAIKDVLARV 361 >5XEP-A nrPDB Length = 381 Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 102/358 (28%), Positives = 169/358 (47%), Gaps = 21/358 (5%) Query: 14 TFFLTLQCSMAQTVVKASYWFPASE----FPVTDIDSSLFTHLFCAFADLNSQTNQVTVS 69 L CS + V + W E F I L TH+ +FA+++S T Sbjct: 12 VLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWE 71 Query: 70 SANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARS 129 ++ + + ++ RN ++KTLLS+GG ++ +ASN R +F+ S RS Sbjct: 72 WNDESNYDKLNK-LKTRNTNLKTLLSVGGWKFGGKRFSEIASNTERRTAFVRSVAPFLRS 130 Query: 130 YGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSV 189 YGF GLDL W YP + F TL++E + E G+ +LLL+AA+ Sbjct: 131 YGFDGLDLAWLYP-RLRDKQYFSTLIKELNAEFTKEV-QPGREKLLLSAALSAGKVAIDT 188 Query: 190 LYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPS-----NAGPSGDAGTRSWIQ 244 Y ++ +A LD++NLM YDF+G W ++TG + LF + + + + I+ Sbjct: 189 GYDIAQIAQHLDFINLMTYDFHGV-WRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIR 247 Query: 245 AGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAI-----SPDGSIGYGQIRKFIVD 299 G A K ++G P +G ++ L ++ + AP +G + G++ Y +I F+ Sbjct: 248 LGAQASKLLMGIPTFGKSFTLASSENQ-LGAPISGEGLPGRFTKEAGTLAYYEICDFLKG 306 Query: 300 NGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 357 + N V + G W+GY+D +S+ KVR+ K++ L G W + DD G Sbjct: 307 AEVHRLSNEKV--PFATKGNQWVGYEDKESVKNKVRFLKEKKLAGAMVWALDLDDFQG 362 >6G9C-A nrPDB Length = 495 Score = 140 bits (354), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 97/322 (30%), Positives = 151/322 (46%), Gaps = 19/322 (5%) Query: 46 SSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRR---NPSVKTLLSIGGGIAD 102 ++L ++F AFA LN + TV V ++ P +K LLS+GG A Sbjct: 59 ANLCEYIFYAFAKLN---DDFTVDQFEWNDIDVLYPGVMKQKSSQPDLKVLLSLGGWNAG 115 Query: 103 KTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAV 162 + MA+ ++R FI S + + F G DLDWEYP S ++ N+ L +E + Sbjct: 116 TATFKKMAATYSNRAKFISSLVSFLQQNKFDGFDLDWEYPES-SDKENYLLLCQEILAKF 174 Query: 163 VAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPP 222 A + RLL AAV + Y V A+A LD+VNLM YDF+G W TG Sbjct: 175 EEVAKCTSTSRLLFTAAVSANPKTVDAGYDVPALAKVLDFVNLMCYDFHG-AWETQTGIN 233 Query: 223 AALFDPSNAGP-----SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPT 277 + L+ + + ++ W G+P K+ ++G P YG W L++A+ AP Sbjct: 234 SPLYSRKEDSSEFKMWNVEQSSKYWSDKGMPKKQIIIGLPTYGRGWTLSDASKTDIGAPA 293 Query: 278 TGAAISPD-----GSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVT 332 G++ + + G I Y ++ + + +GA V++ Y G W YDD +S+ Sbjct: 294 QGSSTATEYLREAGVISYYEVCQ-KLSSGAKRVWDDESKTPYLVQGNQWFSYDDVESMKA 352 Query: 333 KVRYAKQRGLLGYFSWHVGADD 354 K+ + KQ G F W + DD Sbjct: 353 KINWIKQENYGGAFVWTLDYDD 374 >5GZU-A nrPDB Length = 885 Score = 138 bits (347), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 97/342 (28%), Positives = 165/342 (48%), Gaps = 35/342 (10%) Query: 44 IDSSLFTHLFCAFADLNSQ-----------TNQVTVSSA------NQPKFST--FTQTVQ 84 +D++ FTHL+ AF +N+ T T++ A N P S + ++ Sbjct: 45 VDATKFTHLYYAFGRINNGKVVTIKEDAKWTEDPTITEADRIKRRNNPDESNLAYLTGLK 104 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP-- 142 +NP++K L+SIGG A+ ++ A P SR+ F +S++ Y G+DLDWEYP Sbjct: 105 AKNPNLKVLVSIGGWEAE--GFSDAALTPESREVFANSALDFMNKYNLDGIDLDWEYPVY 162 Query: 143 -------SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 S + NF LL+ R + A+++++ K L AA ++ Y+ ++ Sbjct: 163 GAWGVIKSRPEDKANFTALLKLLREKLDAQSTTTNKYYELAIAAG--ASKTYTDSVELTK 220 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLG 255 + LD++NLM YD +G GW T A++ +N S D+ + ++ G+PA+K ++G Sbjct: 221 ITPYLDYINLMTYDLHG-GWDPATSHHTAVYSATNNQLSVDSTVKLYLNNGVPAEKLMVG 279 Query: 256 FPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQ-IRKFIVDNGATTVYNSTVVGDY 314 +Y W+ N + + G+ G+I Y + + +I NG T ++ T Y Sbjct: 280 GAFYSRVWQNVE-NKGTGLSEKAGSQAGSPGTIVYSELVNNYINKNGYTRYWDDTAKAPY 338 Query: 315 CYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNS 356 + G+ +I Y+D S K Y KQ L G+ W D +S Sbjct: 339 LFNGSTFISYEDTASAAYKAEYIKQNNLAGFMYWEYSQDSDS 380 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 97/346 (28%), Positives = 158/346 (45%), Gaps = 45/346 (13%) Query: 44 IDSSLFTHLFCAFADLNSQ----------------TNQVTVSSANQPKFSTFT--QTVQR 85 +D++ TH+ AFA + + ++ N P + F +T+++ Sbjct: 532 VDATKLTHINYAFARIKDNKVVKISEDINWVNEFPSEEIREQRRNNPDDANFAYLKTLKQ 591 Query: 86 RNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP--- 142 +NPS+K L+SIGG A+ ++ A P +R+ +S+I YGF G+DLDWEYP Sbjct: 592 QNPSLKVLVSIGGWAAE--GFSDAALTPETREELANSAIAFMHQYGFDGIDLDWEYPVYG 649 Query: 143 ------SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLL---AAAVFYSNNYYSVLYPV 193 S + NF LL+ +R + E + GK L AAA Y N+ + Sbjct: 650 AFGVIKSRPEDKQNFTALLKLFREKLDVEGALHGKYYELAIASAAAPIYINS-----VEL 704 Query: 194 SAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDP--SNAGPSGDAGTRSWIQAGLPAKK 251 + LD++++M YD++G W T A+++ S S D+ ++ + G+PA K Sbjct: 705 DKIHQYLDYMSVMTYDYHG-SWESKTAHQASVYTSALSPGDFSADSVLTAYRKQGVPASK 763 Query: 252 AVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVV 311 V+G +Y W +H + A +P G+ Y + K D G T ++++ Sbjct: 764 LVIGGAFYARGWVNVPNINHGLFQQAGDQAKNP-GTPTYNDLVKDYFDKGYTRYWDNSAK 822 Query: 312 GDYCY----AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 Y Y G +I YDD +S+ K YAK +GL G W D Sbjct: 823 APYLYNPDANGGTFITYDDEESLKYKAEYAKNQGLRGVMFWDYSQD 868 >5Y29-A nrPDB Length = 377 Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 97/331 (29%), Positives = 155/331 (46%), Gaps = 17/331 (5%) Query: 38 EFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIG 97 ++ DID SL TH+ FA L + + + + + V+ + +K L++G Sbjct: 25 KYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALG 84 Query: 98 G---GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS-ATEMTNFGT 153 G DK Y+ + ++P +R F+ ++ YGF GLDLDWEYP + + Sbjct: 85 GWNDSAGDK--YSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPD 142 Query: 154 LLREWRSAVVAEASSSGKPR-LLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYG 212 ++ + +V E S+ KP+ LLL+AAV + Y V +A LDW+ +M YD++G Sbjct: 143 SDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHG 202 Query: 213 PGWSRVTGPPAALF---DPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNAN 269 W + TG A L+ D + + W++ G PA K V+G P YG ++ + N Sbjct: 203 Q-WDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRG 261 Query: 270 SHSYYAPTT-----GAAISPDGSIGYGQIRKFIVDNGATTVYNS-TVVGDYCYAGTNWIG 323 H P + G G + Y +I I ++G T V + +G Y Y G W+ Sbjct: 262 IHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVS 321 Query: 324 YDDNQSIVTKVRYAKQRGLLGYFSWHVGADD 354 +DD + I KV + K L G W + DD Sbjct: 322 FDDVEIIKKKVNFIKSLNLGGGMIWALDLDD 352 >6BT9-A nrPDB Length = 672 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 91/304 (29%), Positives = 146/304 (48%), Gaps = 35/304 (11%) Query: 81 QTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWE 140 + ++ + P +KT++S+GG ++ MA++ +RK F +S++ R+YGF G+DLDWE Sbjct: 149 KRLKAKYPHLKTIISVGGWTW-SNRFSDMAADEKTRKVFAESTVAFLRAYGFDGVDLDWE 207 Query: 141 YPSSAT---------EMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLY 191 YP T + NF LL++ R+A+ + GK LL A+ ++ Y+ Sbjct: 208 YPGVETIPGGSYRPEDKQNFTLLLQDVRNALNKAGAEDGKQYLLTIASG--ASQRYADHT 265 Query: 192 PVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALF-DPSNAGPSG----DAGTRSWIQAG 246 + ++ LDW+N+M YDF+G GW + AAL+ DP++ + D + G Sbjct: 266 ELKKISQILDWINIMTYDFHG-GWEATSNHNAALYKDPNDPAANTNFYVDGAINVYTNEG 324 Query: 247 LPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIG--------------YGQ 292 +P K VLG P+YG W+ ++ Y P + S G YG Sbjct: 325 VPVDKLVLGVPFYGRGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVYDYGD 384 Query: 293 I-RKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVRYAKQRGLLGYFSWH 349 + ++ NG +N T Y Y T +I YDDN+S+ K Y K +GL G W Sbjct: 385 LAANYVNKNGFVRYWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWE 444 Query: 350 VGAD 353 + D Sbjct: 445 LSGD 448 >3WD0-A nrPDB Length = 503 Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 107/388 (27%), Positives = 175/388 (45%), Gaps = 75/388 (19%) Query: 39 FPVTDI---DSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQ---TVQRRNPSVKT 92 FPV++I + TH+ +F D+NS + N K ++ NPS++ Sbjct: 35 FPVSNITPAKAKQLTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTALKAHNPSLRI 94 Query: 93 LLSIGG-------GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSA 145 + SIGG G++ Y + P +R F S +R+ + YGF G+D+DWEYP +A Sbjct: 95 MFSIGGWYYSNDLGVSHAN-YVNAVKTPAARTKFAQSCVRIMKDYGFDGVDIDWEYPQAA 153 Query: 146 TEMTNFGTLLREWRSAVVAEASSSGKP----RLLLAAA--VFYSNNYYSVLYPVSAVASS 199 E+ F L+E R+ + + + G+ +L +A A F+ + YYS L + + + Sbjct: 154 -EVDGFIAALQEIRTLLNQQTIADGRQALPYQLTIAGAGGAFFLSRYYSKL---AQIVAP 209 Query: 200 LDWVNLMAYDFYGPGWSRVTGPPAALFD------------PSNAGPSGDAGTRSW----- 242 LD++NLM YD GP W ++T AALF +N G S + TR++ Sbjct: 210 LDYINLMTYDLAGP-WEKITNHQAALFGDAAGPTFYNALREANLGWSWEELTRAFPSPFS 268 Query: 243 -----------IQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISP------- 284 + G+P+ K V+G P+YG A++ + + Y+ + P Sbjct: 269 LTVDAAVQQHLMMEGVPSAKIVMGVPFYGRAFKGVSGGNGGQYSSHSTPGEDPYPNADYW 328 Query: 285 -----------DGSIG-YGQIRKFIVDN-GATTVYNSTVVGDYCYAGTN--WIGYDDNQS 329 D I Y Q+ + + N G ++N Y Y N ++ YDD +S Sbjct: 329 LVGCDECVRDKDPRIASYRQLEQMLQGNYGYQRLWNDKTKTPYLYHAQNGLFVTYDDAES 388 Query: 330 IVTKVRYAKQRGLLGYFSWHVGADDNSG 357 K +Y KQ+ L G WH+G D+ +G Sbjct: 389 FKYKAKYIKQQQLGGVMFWHLGQDNRNG 416 >1ITX-A nrPDB Length = 419 Score = 130 bits (328), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 111/391 (28%), Positives = 177/391 (45%), Gaps = 72/391 (18%) Query: 38 EFPVTDIDSSLFTHLFCAFADL----------------------NSQTNQVTVSSA---- 71 + V DID + TH+ AFAD+ N ++ + V + Sbjct: 27 NYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGPNPVTWTCQNEKSQTINVPNGTIVL 86 Query: 72 ----------------NQPKFSTFTQ--TVQRRNPSVKTLLSIGGGIADKTAYASMASNP 113 +QP Q +++ NP++KT++S+GG ++ +A+ Sbjct: 87 GDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPNLKTIISVGGWTW-SNRFSDVAATA 145 Query: 114 TSRKSFIDSSIRVARSYGFHGLDLDWEYPSSA---------TEMTNFGTLLREWRSAVVA 164 +R+ F +S++ R Y F G+DLDWEYP S + N+ LL + R + A Sbjct: 146 ATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDGNSKRPEDKQNYTLLLSKIREKLDA 205 Query: 165 EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAA 224 + GK LL A+ ++ Y+ ++ +A+ +DW+N+M YDF G W +++ A Sbjct: 206 AGAVDGKKYLLTIASG--ASATYAANTELAKIAAIVDWINIMTYDFNG-AWQKISAHNAP 262 Query: 225 L-FDP--SNAG-PSGD-----AGTRSWIQAGLPAKKAVLGFPYYGYAWR-LTNANSHSYY 274 L +DP S AG P + AG + + AG+PA K VLG P+YG W A + Y Sbjct: 263 LNYDPAASAAGVPDANTFNVAAGAQGHLDAGVPAAKLVLGVPFYGRGWDGCAQAGNGQYQ 322 Query: 275 APTTGAAIS--PDGSIGYGQIR-KFIVDNGATTVYNSTVVGDYCYAGTN--WIGYDDNQS 329 T G+++ GS + + +I NG T +N T Y Y +N +I YDD +S Sbjct: 323 TCTGGSSVGTWEAGSFDFYDLEANYINKNGYTRYWNDTAKVPYLYNASNKRFISYDDAES 382 Query: 330 IVTKVRYAKQRGLLGYFSWHVGADDNSGLSR 360 + K Y K +GL G W + D N L Sbjct: 383 VGYKTAYIKSKGLGGAMFWELSGDRNKTLQN 413 >6EPB-A nrPDB Length = 423 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 104/279 (37%), Positives = 149/279 (53%), Gaps = 18/279 (6%) Query: 83 VQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP 142 V++ N +K LLSIGG T + S AS +RK+F ++I + +GF G+D+DWEYP Sbjct: 115 VKKANRGLKVLLSIGGWTW-STNFPSAASTDANRKNFAKTAITFMKDWGFDGIDIDWEYP 173 Query: 143 SSATEMTNFGTLLREWRSAVVAEAS--SSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 + AT+ +N LL+E RS + A A+ + G LL AA +NY + ++ + L Sbjct: 174 ADATQASNMILLLKEVRSQLDAYAAQYAPGYHFLLTIAAPAGKDNYSKLR--LADLGQVL 231 Query: 201 DWVNLMAYDFYGPGWSRVTGPPAALF-DPS--NAGP-SGDAGTRSWIQAGLPAKKAVLGF 256 D++NLMAYD+ G +S +TG A LF +PS NA P + D+ + +I G+PA K VLG Sbjct: 232 DYINLMAYDYAGS-FSPLTGHDANLFNNPSNPNATPFNTDSAVKDYINGGVPANKIVLGM 290 Query: 257 PYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCY 316 P YG +++ T +Y +G+ + G Y + K GAT Y+S G Y Y Sbjct: 291 PIYGRSFQNTAGIGQTYNGVGSGSWEA--GIWDYKALPKA----GATVQYDSVAKGYYSY 344 Query: 317 --AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 A I +D I TKV Y K GL G W AD Sbjct: 345 NSATKELISFDTPDMINTKVAYLKSLGLGGSMFWEASAD 383 >3W4R-A nrPDB Length = 554 Score = 127 bits (320), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 92/344 (26%), Positives = 160/344 (46%), Gaps = 33/344 (9%) Query: 41 VTDIDSSLFTHLFCAFADLNSQTNQVTVSS----ANQPKFSTFTQTVQRRNPSVKTLLSI 96 + DI + TH+ +F + T QV + ++ F FT +++ ++P VK +++ Sbjct: 46 IEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDKNGFKNFT-SLRSKHPGVKFTVAV 104 Query: 97 GGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSA------TEMTN 150 GG + Y+ M + ++R +F+ S + Y F GLDLDWEYP +A ++ Sbjct: 105 GGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFDGLDLDWEYPGAADRGGSFSDKDK 164 Query: 151 FGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDF 210 F L++E R A + E L AAV +N Y V + LD +++M+YD Sbjct: 165 FLYLVQELRRAFIREGKG-----WELTAAVPLANFRLMEGYHVPELCQELDAIHVMSYDL 219 Query: 211 YGPGWSRVTGPPAALFDPSN-----AGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRL 265 G W+ + L+ + + + G + W G P K V+G P+YG ++ L Sbjct: 220 RG-NWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLWEDKGCPTNKLVVGIPFYGRSFTL 278 Query: 266 TNANSH----SYYAPTTGAA-----ISPDGSIGYGQIRKFI--VDNGATTVYNSTVVGDY 314 ++ N++ +Y G + G Y +I + D+ T ++ Y Sbjct: 279 SSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYEICTEVDTADSKWTKKWDEHGKCPY 338 Query: 315 CYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGL 358 Y GT W+GY+D +S+ K+ + K++G LG +W + DD GL Sbjct: 339 AYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAIDMDDFQGL 382 >3WKZ-A nrPDB Length = 395 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 91/347 (26%), Positives = 161/347 (46%), Gaps = 33/347 (9%) Query: 39 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSS----ANQPKFSTFTQTVQRRNPSVKTLL 94 + + DI + TH+ +F + T QV + ++ F FT +++ ++P VK + Sbjct: 26 YGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDKNGFKNFT-SLRSKHPGVKFTV 84 Query: 95 SIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSA------TEM 148 ++GG + Y+ M + ++R +F+ S + Y F GLDLDW+YP +A ++ Sbjct: 85 AVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFDGLDLDWQYPGAADRGGSFSDK 144 Query: 149 TNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAY 208 F L++E R A + E L AAV +N Y V + LD +++M+Y Sbjct: 145 DKFLYLVQELRRAFIREGKG-----WELTAAVPLANFRLMEGYHVPELCQELDAIHVMSY 199 Query: 209 DFYGPGWSRVTGPPAALFDPSN-----AGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAW 263 D G W+ + L+ + + + G + W G P K V+G P+YG ++ Sbjct: 200 DLRG-NWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLWEDKGCPTNKLVVGIPFYGRSF 258 Query: 264 RLTNANSH----SYYAPTTGAA-----ISPDGSIGYGQIRKFI--VDNGATTVYNSTVVG 312 L++ N++ +Y G + G Y +I + D+ T ++ Sbjct: 259 TLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYEICTEVDTADSKWTKKWDEHGKC 318 Query: 313 DYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 Y Y GT W+GY+D +S+ K+ + K++G LG +W + DD GL Sbjct: 319 PYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAIDMDDFQGLC 365 >3G6L-A nrPDB Length = 406 Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 93/279 (33%), Positives = 140/279 (50%), Gaps = 18/279 (6%) Query: 83 VQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP 142 +++ N S+K +LSIGG T + + AS +R +F +++ + +GF G+D+DWEYP Sbjct: 98 LKKANRSLKIMLSIGGWTW-STNFPAAASTEATRATFAKTAVEFMKDWGFDGIDVDWEYP 156 Query: 143 SSATEMTNFGTLLREWRSAVVA-EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLD 201 +S T+ N LL+ R + + A+ + L+ A ++Y+VL ++ + S LD Sbjct: 157 ASETDANNMVLLLQRVRQELDSYSATYANGYHFQLSIAAPAGPSHYNVL-KLAQLGSVLD 215 Query: 202 WVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSG-----DAGTRSWIQAGLPAKKAVLGF 256 +NLMAYD+ G W V+G L+ PS + PS A ++I AG+PA K +LG Sbjct: 216 NINLMAYDYAG-SWDSVSGHQTNLY-PSTSNPSSTPFSTKAAVDAYIAAGVPASKIILGM 273 Query: 257 PYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCY 316 P YG A+ T+ Y T G G Y K + GAT + +S Y Y Sbjct: 274 PIYGRAFVGTDGPGKPY--STIGEGSWESGIWDY----KVLPKAGATVITDSAAGATYSY 327 Query: 317 AGTN--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 ++ I YD + TKV YAK GL G W AD Sbjct: 328 DSSSRTMISYDTPDMVRTKVSYAKGLGLGGSMFWEASAD 366 >1LL6-A nrPDB Length = 392 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 98/338 (28%), Positives = 156/338 (46%), Gaps = 39/338 (11%) Query: 43 DIDSSLFTHLFCAFADLNSQTNQVTVSSA-------------NQPKFSTF-----TQTVQ 84 D+ + FTH+ AFA++ + +V +S ++P + + ++ Sbjct: 23 DLKADQFTHILYAFANIRP-SGEVYLSDTWADTDKHYPGDKWDEPGNNVYGCIKQMYLLK 81 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 144 + N ++KTLLSIGG + + AS RK F D+S+++ + GF G+D++WEYP Sbjct: 82 KNNRNLKTLLSIGGWTYSPN-FKTPASTEEGRKKFADTSLKLMKDLGFDGIDINWEYPED 140 Query: 145 ATEMTNFGTLLREWRSAVVAEASS--SGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDW 202 + +F LL+ R A+ A ++ +GK LL A+ NY + ++ + LD+ Sbjct: 141 EKQANDFVLLLKACREALDAYSAKHPNGKKFLLTIASPAGPQNYNKL--KLAEMDKYLDF 198 Query: 203 VNLMAYDFYGPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSWIQAGLPAKKAVLGFP 257 NLMAYDF G W +V+G + +F PS P S D + +I+AG+PA K VLG P Sbjct: 199 WNLMAYDFSG-SWDKVSGHMSNVF-PSTTKPESTPFSSDKAVKDYIKAGVPANKIVLGMP 256 Query: 258 YYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYA 317 YG A+ T+ S+ G +G Y K + GA + Y Y Sbjct: 257 LYGRAFASTDGIGTSFNG--VGGGSWENGVWDY----KDMPQQGAQVTELEDIAASYSYD 310 Query: 318 GTN--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 I YD + K Y + G+ G W +D Sbjct: 311 KNKRYLISYDTVKIAGKKAEYITKNGMGGGMWWESSSD 348 >5Y2C-A nrPDB Length = 383 Score = 114 bits (286), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 93/342 (27%), Positives = 155/342 (45%), Gaps = 42/342 (12%) Query: 43 DIDSSLFTHLFCAFADLNSQTNQVTVSSAN-----QPKFSTFTQTVQRRNPSVKTLLSIG 97 DI+ L TH+ AFA L+ + ++ + S + + KF + + ++ VK LL +G Sbjct: 26 DINPELCTHIIYAFAVLDKE--ELVIKSHDIWLDVENKF--YEKVTALKSHGVKVLLGLG 81 Query: 98 G---GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS---------A 145 G DK Y+ + +N ++R+ F+ ++ YGF GLDLDW YP Sbjct: 82 GWDDSAGDK--YSRLVNNVSARRKFVVHAVDFLEQYGFDGLDLDWLYPKCWQVECEKGPD 139 Query: 146 TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNL 205 ++ F L++E R A + +LL+AAV S Y V A++ +LDW++L Sbjct: 140 SDKQGFADLVKELRKAF-------NRRGMLLSAAVSASKRVIDYAYNVPALSMNLDWISL 192 Query: 206 MAYDFYGPGWSRVTGPPAALF----DPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGY 261 M YD++G W + TG A ++ D N + + WI G KK V+G P+YG Sbjct: 193 MTYDYHGQ-WDKKTGHVAPMYVHDKDTDNTF-NVNFTVNYWINKGADRKKLVVGVPFYGQ 250 Query: 262 AWRLTNANSHSYYAPTTGAAISPD-----GSIGYGQIRKFIVDNGATTVYN-STVVGDYC 315 ++ + APT + D G + + +I + + G + +G Y Sbjct: 251 SFSVVEGAGTGLGAPTYAGGEAGDETRARGFLSFYEICERVKVKGWKVHRDPGGRIGPYA 310 Query: 316 YAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 357 W+ +DD+ K Y + L G +W + DD +G Sbjct: 311 THDDQWVSFDDDFMARHKAEYVRAMELGGSMAWSLDLDDFTG 352 >3CHF-A nrPDB Length = 433 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 99/336 (29%), Positives = 159/336 (47%), Gaps = 34/336 (10%) Query: 43 DIDSSLFTHLFCAFADLNSQTNQV--TVSSANQPK--------------FSTFTQT--VQ 84 D+ TH+ AFA++ +T +V T S A+ K + Q ++ Sbjct: 63 DLPVERLTHVLYAFANVRPETGEVYMTDSWADIEKHYPGDSWSDTGNNVYGCIKQLYLLK 122 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 144 ++N ++K LLSIGG +A AS RK+F +++++ + GF GLD+DWEYP + Sbjct: 123 KQNRNLKVLLSIGGWTYSPN-FAPAASTDAGRKNFAKTAVKLLQDLGFDGLDIDWEYPEN 181 Query: 145 ATEMTNFGTLLREWRSAVVA-EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWV 203 + +F LL+E R+A+ + A+++G LL A + VL+ + + LD+ Sbjct: 182 DQQANDFVLLLKEVRTALDSYSAANAGGQHFLLTVASPAGPDKIKVLH-LKDMDQQLDFW 240 Query: 204 NLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQ----AGLPAKKAVLGFPYY 259 NLMAYD+ G +S ++G A +++ ++ S T++ + G+PA K VLG P Y Sbjct: 241 NLMAYDYAG-SFSSLSGHQANVYNDTSNPLSTPFNTQTALDLYRAGGVPANKIVLGMPLY 299 Query: 260 GYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT 319 G ++ T+ Y G +G Y K + GAT ++ Y Y T Sbjct: 300 GRSFANTDGPGKPYNG--VGQGSWENGVWDY----KALPQAGATEHVLPDIMASYSYDAT 353 Query: 320 N--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 N I YD+ Q K Y K GL G W +D Sbjct: 354 NKFLISYDNPQVANLKSGYIKSLGLGGAMWWDSSSD 389 >3ARQ-A nrPDB Length = 584 Score = 95.5 bits (236), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 92/334 (27%), Positives = 142/334 (42%), Gaps = 68/334 (20%) Query: 83 VQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFH-GLDLDWEY 141 +++RNP +K + SIGG Y + + +R +F+ S + +++ F+ G+D+DWE+ Sbjct: 238 LKQRNPDLKIIPSIGGWTLSDPFYDFV--DKKNRDTFVASVKKFLKTWKFYDGVDIDWEF 295 Query: 142 PSSATEMTNFG----------TLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLY 191 P + G L+RE R + + +G+ L +A + V Y Sbjct: 296 PGGGGAAADKGDPVNDGPAYIALMRELRVMLDELEAETGRTYELTSAIGVGYDKIEDVDY 355 Query: 192 PVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPS--------------NAGP---- 233 + +D++ M YDFYG GW+ V G AL+ S N P Sbjct: 356 --ADAVQYMDYIFAMTYDFYG-GWNNVPGHQTALYCGSFMRPGQCDGGGVDENGEPYKGP 412 Query: 234 --SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR------LTNANSHSYYAPTTGAA---- 281 + D G + + G+PA K VLG YG W LT+ N P TG A Sbjct: 413 AYTADNGIQLLLAQGVPANKLVLGTAMYGRGWEGVTPDTLTDPND-----PMTGTATGKL 467 Query: 282 -------ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNW---------IGYD 325 + DG I Y I+ F++ T + N G A W I +D Sbjct: 468 KGSTAQGVWEDGVIDYKGIKSFMLGANNTGI-NGFEYGYDAQAEAPWVWNRSTGELITFD 526 Query: 326 DNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 D++S++ K YAK GL G FSW + AD+ L+ Sbjct: 527 DHRSVLAKGNYAKSLGLAGLFSWEIDADNGDILN 560 >5GQB-A nrPDB Length = 553 Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 91/323 (28%), Positives = 144/323 (44%), Gaps = 33/323 (10%) Query: 62 QTNQVTVSSANQPKFSTFTQ--TVQRRNPSVKTLLSIGG-GIADKTAYASMASNPTSRKS 118 Q Q +SS N+P F Q +++ P +K L SIGG +AD + + + T R+ Sbjct: 229 QKPQKGLSSWNEPYKGNFGQLMMLKQAKPDLKILPSIGGWTLADPFFFFT---DETKRRR 285 Query: 119 FIDSSIRVARSYGF-HGLDLDWEYPSSATEMTNFGT---------LLREWRSAVVAEASS 168 F+ S +++ F G+D+DWE+P N G+ L++E R + ++ Sbjct: 286 FVASVKDFLQTWKFFDGVDIDWEFPGGKGANPNLGSPKDGEIYVLLMKELREMLNELSAE 345 Query: 169 SGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVT-GPPAALFD 227 +G+ L +A + V Y SA +D + M+YDF G WS T G A+L+ Sbjct: 346 TGRKYELTSAISAGWDKIQVVDY--SAAQKYMDHIFFMSYDFKG-AWSNDTLGHQASLYA 402 Query: 228 P---SNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISP 284 P + D G + + G+ KK V+G YG W T + + P TG A P Sbjct: 403 PDWNEKETYTTDFGVQFLLAQGVSPKKIVVGVAMYGRGW--TGVHGYKDNNPFTGNATGP 460 Query: 285 ------DGSIGYGQIRKFIVDNGATTVYNSTVVGDYCY--AGTNWIGYDDNQSIVTKVRY 336 DG + Y +I I Y+ Y + A + I YDD +S + K +Y Sbjct: 461 VKGTWQDGVVDYREIATEIAQGKWEYHYDKVAQAPYVFRPATGDLITYDDARSTIEKGKY 520 Query: 337 AKQRGLLGYFSWHVGADDNSGLS 359 + L G F+W + AD+ L+ Sbjct: 521 VRANKLGGLFAWEIDADNGDILN 543 >3QOK-A nrPDB Length = 420 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 103/389 (26%), Positives = 166/389 (42%), Gaps = 83/389 (21%) Query: 41 VTDIDSSLFTHLFCAFA----DLNSQTNQVTVSSAN------QPKFSTFTQTV---QRRN 87 + +D THL +F D +TN A+ PK Q + +++N Sbjct: 46 IDKLDVRQITHLNYSFGLIYNDEKDETNAALKDPAHLHEIWLSPKVQADLQKLPALRKQN 105 Query: 88 PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP----- 142 P +K LLS+GG A ++ A+ SR FI S+ ++ + YG G+DLDWE+P Sbjct: 106 PDLKVLLSVGGWGA--RGFSGAAATAESRAVFIRSAQKIIQQYGLDGIDLDWEFPVNGAW 163 Query: 143 ----SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVAS 198 S + NF LL+ R AV G+ +L+ A + + S + V AVA Sbjct: 164 GLVASQPADRDNFTALLKSLREAV-------GEQKLVTIAVGANAESPKSWV-DVKAVAP 215 Query: 199 SLDWVNLMAYDF-YGPGWSRVTGPPAALFD----PSNAGP---SGDAGTRSWIQAGLPAK 250 L+++NLM YD YG + + L+D P+ A S D +++ AGL Sbjct: 216 VLNYINLMTYDMAYGTQYFN-----SNLYDSSHWPTVAAADKYSADFVVNNYLAAGLKPS 270 Query: 251 KAVLGFPYYGYA----------WRLTNAN----SHSYYAP-------TTGAAISPDGSIG 289 + LG +YG W +A + Y+ P + G +S D + Sbjct: 271 QMNLGIGFYGRVPKRAVEPGIDWTKADAQNNPVTQPYFGPQQIALFASLGYDLSKDTYVK 330 Query: 290 YGQI---------RKFIV--DNGATTVYNS--TVVGDYCYAGTNWIGYDDNQSIVTKVRY 336 Y I ++F D+ A + S + G +A + Y++ +S+ K Y Sbjct: 331 YNDIVGKLLNDPQKRFTEHWDDEAKVPWLSVQSAEGKPLFA----LSYENPRSVAIKADY 386 Query: 337 AKQRGLLGYFSWHVGADDNSGLSRAASQA 365 K +GL G W GADD + L+R +++ Sbjct: 387 IKAKGLAGAMFWEYGADDQNQLARQLAES 415 >5ZL9-A nrPDB Length = 618 Score = 87.4 bits (215), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 83/322 (25%), Positives = 141/322 (43%), Gaps = 29/322 (9%) Query: 62 QTNQVTVSSANQPKFSTFTQ--TVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSF 119 Q Q V++ + P F Q +++ +P +K L SIGG + + R F Sbjct: 213 QKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFF--FMGDKVKRDRF 270 Query: 120 IDSSIRVARSYGF-HGLDLDWEYPSSATEMTNFGT---------LLREWRSAVVAEASSS 169 + S +++ F G+D+DWE+P N G+ L++E R+ + + + Sbjct: 271 VGSVKEFLQTWKFFDGVDIDWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQLSVET 330 Query: 170 GKPRLLLAAAVFYSNNYYSVLYPVSAVA-SSLDWVNLMAYDFYGPGWSRVTGPPAALFDP 228 G+ + L +A+ + Y VA +S+D + LM+YDFYG + G AL P Sbjct: 331 GR-KYELTSAISAGKDKIDKFYSFVNVAQNSMDHIFLMSYDFYGAFDLKNLGHQTALNAP 389 Query: 229 S---NAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISP- 284 + + + G + + G+ K V+G YG W T N + P TG A P Sbjct: 390 AWKPDTAYTTVNGVNALLAQGVKPGKIVVGTAMYGRGW--TGVNGYQNNIPFTGTATGPV 447 Query: 285 -----DGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVRYA 337 +G + Y QI + Y++T Y + + + I +DD +S+ K +Y Sbjct: 448 KGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDARSVQAKGKYV 507 Query: 338 KQRGLLGYFSWHVGADDNSGLS 359 + L G FSW + AD+ L+ Sbjct: 508 LDKQLGGLFSWEIDADNGDILN 529 >5DF0-A nrPDB Length = 545 Score = 84.7 bits (208), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 86/326 (26%), Positives = 144/326 (44%), Gaps = 30/326 (9%) Query: 62 QTNQVTVSSANQPKFSTFTQTVQRR--NPSVKTLLSIGGGIADKTAYASMASNPTSRKSF 119 Q Q +VS+ N+P F Q + + NP +K L SIGG Y + R F Sbjct: 226 QKPQKSVSAWNEPYKGNFGQLMAAKLANPHLKILPSIGGWTLSDPFY--FMHDVEKRNVF 283 Query: 120 IDSSIRVARSYGF-HGLDLDWEYPSSATEMTNFGT----------LLREWRSAVVAEASS 168 +DS + + F G+D+DWE+P + G LL E R+ + + Sbjct: 284 VDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAERDAKTYILLLEELRAMLDDLEAQ 343 Query: 169 SGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVT-GPPAALFD 227 +G+ L +A + V Y + SL + LM+YDF G WS G ++ Sbjct: 344 TGRVYELTSAISAGYDKIAVVNY--AEAQKSLGKIFLMSYDFKG-AWSNTDLGYQTTVYA 400 Query: 228 PS-NAGP--SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR-LTNANSHSYYAPTTGAAIS 283 PS N+ + + ++ G+ K ++G YG W +TN + +Y++ T +S Sbjct: 401 PSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPVS 460 Query: 284 ---PDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVRYAK 338 DG + Y QI+K + N ++S Y + + + I +D S++ KV+Y Sbjct: 461 GTWEDGVVDYRQIQKDL--NNYVYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVD 518 Query: 339 QRGLLGYFSWHVGADDNSGLSRAASQ 364 + L G F+W + AD+ L+ +Q Sbjct: 519 RNKLGGLFAWEIDADNGDLLNAINAQ 544 >1KFW-A nrPDB Length = 435 Score = 82.0 bits (201), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 86/331 (25%), Positives = 137/331 (41%), Gaps = 47/331 (14%) Query: 72 NQPKFSTFTQTVQ--RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRV--- 126 +QP +F Q Q +NP +K ++S+GG K ++ A+ SR+ + S I + Sbjct: 98 DQPLAGSFNQLKQLKAKNPKLKVMISLGGWTWSKN-FSKAAATEASRQKLVSSCIDLYIK 156 Query: 127 -------ARSYG------FHGLDLDWEYP-----------SSATEMTNFGTLLREWRSAV 162 R F G+D+DWE+P + + NF LL E+R + Sbjct: 157 GNLPNFEGRGGAGAAAGIFDGIDIDWEWPGTNSGLAGNGVDTVNDRANFKALLAEFRKQL 216 Query: 163 VAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPP 222 A S++ K +L A + + + A SLD+ ++ YD +G +TG Sbjct: 217 DAYGSTNNKKYVLSAFLPANPADIDAGGWDDPANFKSLDFGSIQGYDLHGAWNPTLTGHQ 276 Query: 223 AALFDPSNAGP-------SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYA 275 A L+D A P S D + ++ AG+ K+ LG YG W T A + S + Sbjct: 277 ANLYDDP-ADPRAPSKKFSADKAVKKYLAAGIDPKQLGLGLAAYGRGW--TGAKNVSPWG 333 Query: 276 PTTGAAIS--PDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTK 333 P T A + Y +++ D+ Y++ + Y GT W YD+ + K Sbjct: 334 PATDGAPGTYETANEDYDKLKTLGTDH-----YDAATGSAWRYDGTQWWSYDNIATTKQK 388 Query: 334 VRYAKQRGLLGYFSWHVGADDNSGLSRAASQ 364 Y +GL G W + D N L A S Sbjct: 389 TDYIVSKGLGGGMWWELSGDRNGELVGAMSD 419 >6F8N-A nrPDB Length = 414 Score = 81.6 bits (200), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 101/390 (25%), Positives = 154/390 (39%), Gaps = 85/390 (21%) Query: 41 VTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQP----------KFSTFTQ---TVQRRN 87 + +D + THL +F + + Q T + P K Q ++++N Sbjct: 31 INKLDVTQITHLNYSFGLIYNDEKQETNPALKDPSRLHQIYLSPKVMADLQLLPVLRKQN 90 Query: 88 PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP----- 142 P +K LLS+GG A ++ A+ SR FI S +V + Y G+DLDW+YP Sbjct: 91 PELKVLLSVGGWGA--RGFSGAAATAESRAVFIRSVQQVIKQYHLDGIDLDWQYPVNGAW 148 Query: 143 ----SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVAS 198 S + NF LL E A+ GK LL AV + V +A Sbjct: 149 GLVESQPADRANFTLLLAELHKAL-----DKGK---LLTIAVGANVKSPQEWVDVKGIAP 200 Query: 199 SLDWVNLMAYDF-YGPGWSRVTGPPAALFDPSNAGPSGDAGTR--------SWIQAGLPA 249 LD++NLM YD YG + + L+D S P+ A R +++ AGL Sbjct: 201 YLDYINLMTYDMAYGTQYFN-----SNLYD-SKQWPTVAAADRYSANFVVDNYLAAGLKP 254 Query: 250 KKAVLGFPYYGYA----------WRLTNANSHSYYAP-----------TTGAAISPDGSI 288 + LG +YG W +A + P G ++ D Sbjct: 255 AQLNLGIGFYGRVPKRATEPGIDWDKADAAKNPVTQPYFTARETAVFKAMGLDLTKDSYF 314 Query: 289 GYGQI---------RKFIV--DNGATTVY--NSTVVGDYCYAGTNWIGYDDNQSIVTKVR 335 Y I R+F D+ A Y + G +A I Y++ +S+ K Sbjct: 315 KYNDIVSKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKPLFA----ISYENPRSVALKAD 370 Query: 336 YAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 Y K +GL G W GADDN+ L+ +++ Sbjct: 371 YIKSKGLGGAMFWEYGADDNNRLAHQLAES 400 >4TXG-A nrPDB Length = 793 Score = 80.9 bits (198), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 91/343 (26%), Positives = 136/343 (39%), Gaps = 89/343 (25%) Query: 42 TDIDSSLFTHLFCAFADLNSQTNQVTVSS---------------------ANQP---KFS 77 +DI S TH+ AFA ++ +N+++V+ A+ P F+ Sbjct: 176 SDIPWSKLTHINYAFAHVDG-SNKLSVNETAPGNPATDMSWPGVAGAEMDASLPYKGHFN 234 Query: 78 TFTQTVQRRNPSVKTLLSIGG------------------GIADKTAYASMASNPTSRKSF 119 TQ +R+ P VKTL+S+GG G T A N +F Sbjct: 235 LLTQ-YKRKYPGVKTLISVGGWAETGGYFDANGKRVASGGFYSMTVNADGTVNQAGINAF 293 Query: 120 IDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLL---- 175 DS++ R YGF G+D+D+EYP+S M N G L S + + G LL Sbjct: 294 SDSAVAFLRKYGFDGVDIDFEYPTS---MNNAGNPLDWTFSNARLGSLNKGYVALLQTLR 350 Query: 176 --LAAAVFYSNNYYSVLYPVSAVA------------SSLDWVNLMAYDFYGPGWSRVTGP 221 L A YY + V A LD+VN+M+YD +G W+R GP Sbjct: 351 DRLDRAAAQDGRYYQITAAVPASGYLLRGMETFQGLKYLDFVNVMSYDLHG-AWNRFVGP 409 Query: 222 PAALFDP-----------------SNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR 264 AAL+D N G + + GLPA + +G PYY W+ Sbjct: 410 NAALYDDGKDAELAFWNVYSTPQYGNIGYLNTDWAYHYYRGGLPASRVNMGVPYYTRGWK 469 Query: 265 LTNANSHSYYAPTTGAAISP------DGSIGYGQIRKFIVDNG 301 + S+ + + G+ DG++G I + D+G Sbjct: 470 NVSGGSNGLWGSSVGSNCPAGLTECGDGAVGIDNIWHDLDDSG 512 >5Z7M-A nrPDB Length = 546 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 81/321 (25%), Positives = 138/321 (42%), Gaps = 29/321 (9%) Query: 62 QTNQVTVSSANQPKFSTFTQ--TVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSF 119 Q Q V++ + P F Q +++ +P +K L SIGG + + R F Sbjct: 213 QKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFF--FMGDKVKRDRF 270 Query: 120 IDSSIRVARSYGF-HGLDLDWEYPSSATEMTNFGT---------LLREWRSAVVAEASSS 169 + S +++ F G+D+ WE+P N G+ L++E R+ + + + Sbjct: 271 VGSVKEFLQTWKFFDGVDIAWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQLSVET 330 Query: 170 GKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPS 229 G+ L +A + V Y V+ +S+D + LM+YDFYG + G AL P+ Sbjct: 331 GRKYELTSAISAGKDMIDKVAYNVAQ--NSMDHIFLMSYDFYGAADLKNLGHQTALNAPA 388 Query: 230 ---NAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISP-- 284 + + G + + G+ K V+G YG W T N + P TG A P Sbjct: 389 WKPDTAYTTVNGVNALLAQGVKPGKIVVGTAMYGRGW--TGVNGYQNNIPFTGTATGPVK 446 Query: 285 ----DGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVRYAK 338 +G + Y QI + Y++T Y + + + I +DD +S+ K +Y Sbjct: 447 GTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDARSVQAKGKYVL 506 Query: 339 QRGLLGYFSWHVGADDNSGLS 359 + L G FS + AD+ L+ Sbjct: 507 DKQLGGLFSAMIDADNGDILN 527 >5XWF-A nrPDB Length = 378 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 91/351 (25%), Positives = 142/351 (40%), Gaps = 57/351 (16%) Query: 49 FTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYAS 108 H+ AFA+ T +S + + Q R S+ LS+GG ++ Sbjct: 22 LDHIVYAFAE---PTKDGELSGFTDSQLKSVVQEAHSRGKSIS--LSVGGWTG-SLYFSD 75 Query: 109 MASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----------ATEMTNFGTLLREW 158 + + +S +F+ + + V + Y GL+LDWEYP+S + N+ L + Sbjct: 76 LLKSSSSFDNFVSNLVDVVKEYDLDGLNLDWEYPNSPNGVACNSKDENDTANYLKLFKAL 135 Query: 159 RSAVVAEASSSGKPRLLLAA---AVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGW 215 R + G +L A A F N AS++D +MAYD G Sbjct: 136 REKL-------GSKTILTTAVPTAPFNDENQQPSTKLDDNWASTVDAFYIMAYDVNGIR- 187 Query: 216 SRVTGPPAAL-FDPSNAG---PSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTN--AN 269 + G A L + P G SG+ ++WI AG+PA++ VLG P+YG + Sbjct: 188 DKNAGANAPLYYSPKVTGVEPTSGNDAVKAWIAAGIPAEQLVLGVPFYGRVSKTLEPITA 247 Query: 270 SHSYYAPTT-------------GAAISPDGSIGY-GQ-IRKFIVDNGA-------TTVYN 307 S Y P + A P+ Y GQ I + I G T ++ Sbjct: 248 STGLYVPISQSSQIKGDSTDEKAADPCPNAVATYSGQYIWRTIAQEGIARNSSGWVTYWD 307 Query: 308 STVVGDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNS 356 Y Y +G+ + +DD S+ KV YAK++GL G W + DD+ Sbjct: 308 DISKTPYAYSFSGSKVLSFDDAASLQDKVDYAKKQGLGGVMLWSLEMDDDE 358 >4W5U-B nrPDB Length = 408 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 83/312 (26%), Positives = 122/312 (39%), Gaps = 43/312 (13%) Query: 72 NQPKFSTFTQTVQRRN--PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARS 129 +QP F Q Q + P +K L S GG +A A +P + + R Sbjct: 113 DQPLRGNFNQLRQLKAKYPHIKVLWSFGGWTW-SGGFADAAKDPQGFAQSCYNLVHDPRW 171 Query: 130 YG-FHGLDLDWEYPSSATEMTN------FGTLLREWRSA-----VVAEASSSGKPRLLLA 177 G F G+D+DWEYP++ + F L+ RS V A ++ G P + Sbjct: 172 DGVFDGIDIDWEYPNACGLTCDSSGPDAFRNLMAALRSTFGDELVTAAVTADGTPGGKIE 231 Query: 178 AAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGP-----PAALFD--PSN 230 A + + A +DW N+M YDF+G W GP P +D P Sbjct: 232 ATDY------------AGAAQYVDWYNVMTYDFFG-AWD-AQGPTAPHSPLTSYDGIPKQ 277 Query: 231 AGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGY 290 S DA ++ G+PA K +LG +YG W ++ G A P Sbjct: 278 GFTSADA-IAAFKAQGVPADKLLLGIGFYGRGWTGVTQDAPG------GTATGPAAGTWE 330 Query: 291 GQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHV 350 I + V V + Y + G+N YD +I +K+ +A +GL G F+W Sbjct: 331 QGIEDYKVLKNTCPVTGTVAGTAYAHCGSNLWSYDTPDTIASKMAWANDQGLRGAFAWDF 390 Query: 351 GADDNSGLSRAA 362 D G AA Sbjct: 391 SGDTADGELIAA 402 >6OGD-C nrPDB Length = 633 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 75/296 (25%), Positives = 131/296 (44%), Gaps = 31/296 (10%) Query: 98 GGIADKTAYASMASNPTSRKSFIDSSIRV-ARSYGFHGLDLDWEYP---------SSATE 147 GG + + ++++A NP R+ F+ S + R F +D+DWEYP SS + Sbjct: 306 GGWSLSSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGDEGNISSDKD 365 Query: 148 MTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMA 207 N+ L++E RSA+ + S + + +A + + S + + VA+ LD + LM+ Sbjct: 366 GENYVLLIKELRSALDSRFGYSNRKEISIACSGVKAKLKKSNIDQL--VANGLDNIYLMS 423 Query: 208 YDFYGPGWSRVTGPPAALFDPSNAGPSG--DAGTRSWI-----QAGLPAKKAVLGFPYYG 260 YDF+G W+ G L+ P + G D + I + G+P +K LG+ YG Sbjct: 424 YDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELGIPMEKIHLGYANYG 483 Query: 261 YAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVD---------NGATTVYNSTVV 311 + + + Y +G+ + I K +D NG + ++ Sbjct: 484 RSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSMGKNGFVLMTDTNAD 543 Query: 312 GDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 D+ + A ++I D +++ K YA + L G FSW G D L+ AA + Sbjct: 544 ADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWS-GDQDCGLLANAAREG 598 >4DWS-C nrPDB Length = 546 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 75/296 (25%), Positives = 131/296 (44%), Gaps = 31/296 (10%) Query: 98 GGIADKTAYASMASNPTSRKSFIDSSIRV-ARSYGFHGLDLDWEYP---------SSATE 147 GG + + ++++A NP R+ F+ S + R F +D+DWEYP SS + Sbjct: 219 GGWSLSSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGDEGNISSDKD 278 Query: 148 MTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMA 207 N+ L++E RSA+ + S + + +A + + S + + VA+ LD + LM+ Sbjct: 279 GENYVLLIKELRSALDSRFGYSNRKEISIACSGVKAKLKKSNIDQL--VANGLDNIYLMS 336 Query: 208 YDFYGPGWSRVTGPPAALFDPSNAGPSG--DAGTRSWI-----QAGLPAKKAVLGFPYYG 260 YDF+G W+ G L+ P + G D + I + G+P +K LG+ YG Sbjct: 337 YDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELGIPMEKIHLGYANYG 396 Query: 261 YAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVD---------NGATTVYNSTVV 311 + + + Y +G+ + I K +D NG + ++ Sbjct: 397 RSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSMGKNGFVLMTDTNAD 456 Query: 312 GDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 D+ + A ++I D +++ K YA + L G FSW G D L+ AA + Sbjct: 457 ADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWS-GDQDCGLLANAAREG 511 >1JNE-A nrPDB Length = 420 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 89/382 (23%), Positives = 147/382 (38%), Gaps = 66/382 (17%) Query: 40 PVTDIDSSLFTHLFCAFADLNSQTNQVTVSSAN----QPKFSTFTQTVQRRNPSVKTLLS 95 P +I +HL +A L + Q + N + +FS T +++R+ P +K LLS Sbjct: 24 PDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKHQFSEVT-SLKRKYPHLKVLLS 82 Query: 96 IGGGIA----DKTAYASMASNPTSRK-SFIDSSIRVARSYGFHGLDLDWEYPSSATEMTN 150 +GG Y + R+ FI S+ + ++YGF GLDL +++P + + Sbjct: 83 VGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYELVKTYGFDGLDLAYQFPKNKPRKVH 142 Query: 151 ----------------------FGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYS 188 L +E +A+V + S + L + N + Sbjct: 143 GDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDVKDSLRADGFLLSLTVLPNVNST 202 Query: 189 VLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGP-PAALFDPSN-----AGPSGDAGTRSW 242 + + A+ +D+VNL +DF P + A ++ P A + D W Sbjct: 203 WYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPIYHPDGSKDRLAHLNADFQVEYW 262 Query: 243 IQAGLPAKKAVLGFPYYGYAWRLTNAN---------SHSYYAPTTGAAISPDGSIGYGQI 293 + G P+ K LG YG AW+LT + S AP + P G + Y +I Sbjct: 263 LSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPETSGPAPEGFQSQKP-GLLSYAEI 321 Query: 294 --------RKFIVDNGA--TTVYNSTV-VGDYCYAGTN-------WIGYDDNQSIVTKVR 335 +F+ N + V + T G Y + W+ YDD S K Sbjct: 322 CGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAA 381 Query: 336 YAKQRGLLGYFSWHVGADDNSG 357 YA+ + L G + + DD G Sbjct: 382 YARVKNLGGVALFDLSYDDFRG 403 >4A5Q-A nrPDB Length = 546 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 90/373 (24%), Positives = 141/373 (37%), Gaps = 72/373 (19%) Query: 39 FPVTDIDSSLFTHLFCAF-----ADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTL 93 PV D D ++ + C F D N + NQ F + + + ++ Sbjct: 160 IPV-DPDGAVLASINCGFTKWEAGDANERYNQEKAKGL----LGGF-RLLHEADKELEFS 213 Query: 94 LSIGG----GIADKTAYASMASNPTSRKSFIDSSIRVARSYG-FHGLDLDWEYP------ 142 LSIGG G+ ++ +A + R +F++ + + F LD+DWEYP Sbjct: 214 LSIGGWSMSGL-----FSEIAKDEILRTNFVEGIKDFFQRFPMFSHLDIDWEYPGSIGAG 268 Query: 143 --SSATEMTNFGTLLREWRSAVVAE-----ASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 +S + NF L+++ A ++ +SS P + AA + + Sbjct: 269 NPNSPDDGANFAILIQQITDAKISNLKGISIASSADPAKIDAANI------------PAL 316 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPS---GDAGTRSWIQAGLPAKKA 252 + + + +NLM YDF+ G +++ DPS+ DA T + + K Sbjct: 317 MDAGVTGINLMTYDFFTLGDGKLSHHTNIYRDPSDVYSKYSIDDAVTHLIDEKKVDPKAI 376 Query: 253 VLGFPYYGYAWRLTNAN------SHSYYAPTTGAAISPDGSIGYG------------QIR 294 +G Y GY NA S T A GS Y Sbjct: 377 FIG--YAGYTRNAKNATITTSIPSEEALKGTYTDANQTLGSFEYSVLEWTDIICHYMDFE 434 Query: 295 KFIVDNGATTVYNSTVVGDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGA 352 K NG V++ DY Y A +I D +S+ K RY K +GL G F W G Sbjct: 435 KGEGRNGYKLVHDKVAKADYLYSEATKVFISLDTPRSVRDKGRYVKDKGLGGLFIWS-GD 493 Query: 353 DDNSGLSRAASQA 365 DN L+ AA + Sbjct: 494 QDNGILTNAAHEG 506 >3CZ8-A nrPDB Length = 319 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 33/243 (13%) Query: 47 SLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAY 106 S+F + D+ +Q N + T QRR + T+ ++ G Sbjct: 37 SIFEYHIAPNGDIANQLNDA----------AAIETTWQRRVTPLATITNLTSGGFSTEIV 86 Query: 107 ASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEA 166 + +NPT+R + +++ + + G+ G+ +D+E SA + F LR+ R + A Sbjct: 87 HQVLNNPTARTNLVNNIYDLVSTRGYGGVTIDFE-QVSAADRDLFTGFLRQLRDRLQA-- 143 Query: 167 SSSGKPRLLLAAAVFYSNNY-YSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAAL 225 G L +A S+N + Y + + ++++ +MAYD++ G GP A + Sbjct: 144 ---GGYVLTIAVPAKTSDNIPWLRGYDYGGIGAVVNYMFIMAYDWHHAGSE--PGPVAPI 198 Query: 226 FDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPD 285 + T + A +P++K ++G P YGY W + Y T +AIS Sbjct: 199 TEIRR--------TIEFTIAQVPSRKIIIGVPLYGYDWII------PYQPGTVASAISNQ 244 Query: 286 GSI 288 +I Sbjct: 245 NAI 247 >4Q6T-A nrPDB Length = 351 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 64/250 (25%), Positives = 103/250 (41%), Gaps = 38/250 (15%) Query: 120 IDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAA 179 + +++A+ GF G++LD+E E N ++ A +S+ K + + Sbjct: 102 VKQLVKLAKEGGFAGINLDFE----KVEPRNRAAFCAFVKTLGNALHASNKKLIISIPPK 157 Query: 180 VFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGT 239 + + Y Y A+ +++D+ +M YD GPGWS + F + A P ++G Sbjct: 158 LSDTEPEYLQGYDYKALGAAVDYFQVMTYDQVGPGWS------SGGFH-NEAWPGPESGF 210 Query: 240 RSWIQAGL-------PAKKAVLGFPYYGYAWRLTNANSHSYYAPTTG---AAISPDGSIG 289 W QA L PA K + G P YG + + N S Y AAI D + Sbjct: 211 -DWQQALLSYAVSRVPASKVLAGLPTYGQDYSIGNRVHWSAYQEIIAEHRAAIHRDAASA 269 Query: 290 -----YGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLG 344 +G ++ F VD T + V + YDD SI TK + GL G Sbjct: 270 TPYATWGPVKSF-VDGVEWTPERAQPV----------LWYDDAASIKTKTALVTRLGLGG 318 Query: 345 YFSWHVGADD 354 W +G ++ Sbjct: 319 TSVWAMGYEN 328 >3CO4-A nrPDB Length = 312 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 71/325 (21%), Positives = 124/325 (38%), Gaps = 59/325 (18%) Query: 33 WFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKT 92 W S FP I+ TH+ +FA + + + ++ + + + +T + N VK Sbjct: 15 WEFESLFPT--IEWKYLTHINASFARVKAD-GTLNINPV-RKRIESVRETAHKHN--VKI 68 Query: 93 LLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFG 152 L+S+ + + ++P +RK I I + Y G D+D+E + + NF Sbjct: 69 LISLAKN--SPGEFTTAINDPKARKELIQQIIAFTKEYKLDGFDIDYEEYDNWDK--NFP 124 Query: 153 TLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYG 212 +LL R +A+ + +L+ AV N+ + L + D++NLM+YD Sbjct: 125 SLLVFARGLYLAKEKN-----MLMTCAV---NSRW--LNYGTEWEQYFDYINLMSYD--- 171 Query: 213 PGWSRVTGPPAALFDPSNAGPSGD---AGTRSWIQAGLPAK-KAVLGFPYYGYAWRLTNA 268 A D S D + W + +K K V G P+YGY+W Sbjct: 172 ---------RGAFTDKPVQHASYDDFVKDLKYWNEQCRASKSKIVGGLPFYGYSWE---- 218 Query: 269 NSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQ 328 + A+ I Y I K + + A + +G Y G Sbjct: 219 -------ESLQGAVDDVRGIRYSGILKHLGNEAA----DKDNIGKTYYNGR--------P 259 Query: 329 SIVTKVRYAKQRGLLGYFSWHVGAD 353 +I K ++ K+ G W + D Sbjct: 260 TIANKCKFIKENDYAGVMIWQLFQD 284 >4S3J-A nrPDB Length = 433 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/260 (22%), Positives = 105/260 (40%), Gaps = 64/260 (24%) Query: 114 TSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATE-MTNFGTLLREWR----------SAV 162 T + FI + ++ A YG + D+E S A E + LR + + + Sbjct: 194 TIQNKFITNILQTAEKYGMRDIHFDFE--SVAPEDREAYNRFLRNVKIRLPSGYTLSTTL 251 Query: 163 VAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPP 222 V + SS+ K + F +++Y A +D+V +M YD+ GW GPP Sbjct: 252 VPKTSSNQKGKF------FEAHDY-------KAQGQIVDFVVIMTYDW---GWQ--GGPP 293 Query: 223 AALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAI 282 A+ S GP + + ++ +P +K ++G YG+ W+L + A+ Sbjct: 294 MAI---SPIGPVKEV--LQYAKSQMPPQKIMMGQNLYGFDWKLPFKQGNP-----PAKAV 343 Query: 283 SPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDN-----------QSIV 331 S ++ RK YN + D+ ++ +D+N +SI Sbjct: 344 SSVAAVALA--RK----------YNVPIRYDFTAQAPHFNYFDENGVQHEVWFEDARSIQ 391 Query: 332 TKVRYAKQRGLLGYFSWHVG 351 +K K++G+ G W +G Sbjct: 392 SKFNLMKEQGIGGISYWKIG 411 >4WIW-A nrPDB Length = 349 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 57/274 (20%), Positives = 110/274 (40%), Gaps = 51/274 (18%) Query: 108 SMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTN----FGTLLREWRSAVV 163 ++ +P +R+ I + + ++ G+ +D+E P ++ + L + ++ Sbjct: 89 TLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLH 148 Query: 164 AEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPA 223 +E S K ++ S+ Y+ Y A++ ++D++++M YD + R + P Sbjct: 149 SELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHH----YRTSAP-- 202 Query: 224 ALFDPSNAGPSGDAGTRSWIQA--------GLPAKKAVLGFPYYGYAWRL--TNANSHSY 273 G WI+ G+ K ++G PYYG W + +AN + Sbjct: 203 -----------GPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPT 251 Query: 274 YAPTTGAAISPDGSIGYGQIRKFIVDNGATTVY----NSTVVGDYCYAGTNWIG------ 323 Y T + GY + + GAT Y ++ VG + T+ G Sbjct: 252 YNST---------AFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVF 302 Query: 324 YDDNQSIVTKVRYAKQRGLLGYFSWHVG-ADDNS 356 +DD S K+ + GL G W +G D+N+ Sbjct: 303 FDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENT 336 >4S3K-A nrPDB Length = 436 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 58/268 (21%), Positives = 107/268 (39%), Gaps = 44/268 (16%) Query: 98 GGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLRE 157 G +D+ A + +N + + +++ ++ A+ F + D+E+ A + + L++ Sbjct: 180 GAFSDEVGRAIL-NNKDVQDTLLNNIVKTAKEQNFRDIHFDFEFLRPADKEA-YIAFLQK 237 Query: 158 WRSAVVAEASSSGKPRLLLAAAVF------YSNNYYSVLYPVSAVASSLDWVNLMAYDFY 211 + + E +LL++ A+ +Y + A+ ++V M Y+ Sbjct: 238 AKKRLQDE-------QLLMSVALAPKTSRDQKGKWYEA-HDYKAIGEIANFVVPMTYE-- 287 Query: 212 GPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSH 271 W GPP A+ S GP D + + +P+ K ++G YGY W L Sbjct: 288 ---WGYSGGPPMAV---SPIGPVRD--VLEYAVSEIPSSKIIMGQNLYGYDWTLPYKPGG 339 Query: 272 SYYAPTTGAAISPDGSIGYGQIRKFIV--DNGATTVYNSTVVGDYCYAG----TNWIGYD 325 Y AISP +I K + DN A + + Y T+ + ++ Sbjct: 340 EY-----AKAISPQRAIELAARYKVAIQYDNKAQAPF-------FRYKDEQQRTHEVWFE 387 Query: 326 DNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 D +SI K K+ L G W +G D Sbjct: 388 DARSIQAKFDLIKELKLRGMAYWKLGLD 415 >3IAN-A nrPDB Length = 321 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 7/105 (6%) Query: 77 STFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLD 136 + F + + N K++L GG A A + + F++ IR+ +YGF GLD Sbjct: 66 TEFRAEISKLNAEGKSVLIALGG-----ADAHIELKKSQESDFVNEIIRLVDTYGFDGLD 120 Query: 137 LDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVF 181 +D E +A E + T++ V GK ++ A F Sbjct: 121 IDLE--QAAIEAADNQTVIPSALKKVKDHYRKDGKNFMITMAPEF 163 >5JH8-A nrPDB Length = 317 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 37/151 (24%), Positives = 70/151 (46%), Gaps = 33/151 (21%) Query: 124 IRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYS 183 ++ A+ F G+++D+E + + NF ++ V+ A + +L+++ F + Sbjct: 97 VKFAQDKRFSGINVDFEAVAQG-DRNNFSHFIQ-----VLGRALHAKGLKLIVSVPAFSA 150 Query: 184 ---NNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTR 240 N+ + Y + A+ ++ D++ +M+YD P W DP GP AG+ Sbjct: 151 KDENHPANYGYDLRALGAAADYLQIMSYDEAIPAW-----------DP---GPV--AGS- 193 Query: 241 SWIQAGL-------PAKKAVLGFPYYGYAWR 264 W++ L PA K + G P YGY W+ Sbjct: 194 DWMEDDLDYAVERVPAAKILNGIPAYGYDWK 224 >4TX8-A nrPDB Length = 439 Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 13/109 (11%) Query: 36 ASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ----RRNPSVK 91 S FP++ + S+ + + AFAD N VS P + Q +Q ++ K Sbjct: 121 GSAFPLSQV-SADWDVIVVAFADDAGNGN---VSFTLDPAAGSAAQFIQDIRAQQAKGKK 176 Query: 92 TLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWE 140 +LS+GG T +N T ++F++S + YGF G+DLD E Sbjct: 177 VVLSLGGQNGSVTL-----NNATQVQNFVNSLYGILTQYGFDGIDLDLE 220 >4AXN-A nrPDB Length = 328 Score = 37.0 bits (84), Expect = 0.015, Method: Compositional matrix adjust. Identities = 60/233 (25%), Positives = 86/233 (36%), Gaps = 52/233 (22%) Query: 56 FADLNSQTNQVTVSSANQPKFSTF-----TQTVQRRNPSV------KTLLSIGGGIADKT 104 D+ ++ N V V+ TF + T RR V L+S+GG Sbjct: 52 LTDIPTEYNVVAVAFMKGQGIPTFKPYNLSDTEFRRQVGVLNSQGRAVLISLGG------ 105 Query: 105 AYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVA 164 A A + D IR+ YGF GLD+D E +A N T+L V Sbjct: 106 ADAHIELKTGDEDKLKDEIIRLVEVYGFDGLDIDLE--QAAIGAANNKTVLPAALKKVKD 163 Query: 165 EASSSGKPRLLLAAAVFYSNNYYSVLYP-VSAVASSLDWVNLMA--YDFYGPGWSRVTGP 221 ++ GK ++ A F P + + LD++N + YDF P + G Sbjct: 164 HYAAQGKNFIISMAPEF----------PYLRTNGTYLDYINALEGYYDFIAPQYYN-QGG 212 Query: 222 PAALFDPSNA--GPSGDA---------------GTRSWIQAGLPAKKAVLGFP 257 D NA + DA GTR + A +PA K V+G P Sbjct: 213 DGIWVDELNAWITQNNDAMKEDFLYYLTESLVTGTRGY--AKIPAAKFVIGLP 263 >3EBV-A nrPDB Length = 302 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 11/114 (9%) Query: 41 VTDIDSSLFTHLFCAFADLNSQTNQVT--VSSANQPKFST--FTQTVQRRNPS-VKTLLS 95 ++D+ S+ + + AFAD + VT + SA ++ F V+ + + K ++S Sbjct: 23 ISDVPSA-YDIIAVAFADATTTPGAVTFNLDSAGLGGYTVDQFKADVRAKQAAGKKVIIS 81 Query: 96 IGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMT 149 +GG + +S S +F +S V R YGF G+D+D E + T MT Sbjct: 82 VGGEKGTVSVNSS-----ASATNFANSVYSVMREYGFDGVDIDLENGLNPTYMT 130 >1MW7-A nrPDB Length = 240 Score = 31.6 bits (70), Expect = 0.65, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 266 TNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTV-VGDYCYAGTNWIGY 324 T AN SY+ T GA+I P+GS+ + RK + + V N + + D +A ++ G Sbjct: 105 TIANLKSYFNKTQGASIVPNGSLEFMFNRKSVFECLKNEVENLKLSLEDLEFALIDY-GL 163 Query: 325 DDNQSIVTKV 334 ++ + + K+ Sbjct: 164 EELEEVEDKI 173 >3SIM-A nrPDB Length = 275 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 83 VQRRNPSVKTLLSIGGG-IADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEY 141 ++ +P+V+ +S+GG + T AS + + + S R+ + Y G+D+D+E+ Sbjct: 69 IKSSHPNVRVAVSLGGASVGSNTVQFQAASVDSWVSNAVTSLTRIIQRYNLDGIDIDYEH 128 >4EPS-A nrPDB Length = 510 Score = 28.5 bits (62), Expect = 5.3, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 17/27 (62%) Query: 291 GQIRKFIVDNGATTVYNSTVVGDYCYA 317 G+ ++F+VD G V + VGDY YA Sbjct: 250 GKYKRFVVDGGYKEVTHHLQVGDYYYA 276 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3AQU-A nrPDB 461 e-130 1WB0-A nrPDB 398 e-111 3RM8-A nrPDB 393 e-110 4WKA-A nrPDB 392 e-109 5WV8-A nrPDB 390 e-109 5WUS-A nrPDB 390 e-109 5XEP-A nrPDB 389 e-108 1HJW-A nrPDB 384 e-107 3ALF-A nrPDB 384 e-107 2QF8-A nrPDB 382 e-106 1E9L-A nrPDB 367 e-102 4MNK-A nrPDB 362 e-100 4P8U-A nrPDB 358 1e-99 5Y29-A nrPDB 341 4e-94 6G9C-A nrPDB 339 1e-93 4URI-A nrPDB 337 4e-93 3W4R-A nrPDB 333 6e-92 3WKZ-A nrPDB 324 5e-89 5Y2C-A nrPDB 320 7e-88 1ITX-A nrPDB 311 3e-85 5GZU-A nrPDB 306 9e-84 6BT9-A nrPDB 301 2e-82 3CHF-A nrPDB 292 2e-79 5ZL9-A nrPDB 290 8e-79 5GQB-A nrPDB 288 2e-78 5Z7M-A nrPDB 286 1e-77 3G6L-A nrPDB 285 3e-77 6EPB-A nrPDB 284 4e-77 1LL6-A nrPDB 283 6e-77 3WD0-A nrPDB 276 8e-75 5DF0-A nrPDB 267 7e-72 6F8N-A nrPDB 260 6e-70 3ARQ-A nrPDB 260 7e-70 1KFW-A nrPDB 257 5e-69 3QOK-A nrPDB 251 4e-67 1JNE-A nrPDB 233 8e-62 4W5U-B nrPDB 231 3e-61 4DWS-C nrPDB 231 3e-61 6OGD-C nrPDB 229 1e-60 5XWF-A nrPDB 227 6e-60 4A5Q-A nrPDB 221 5e-58 4TXG-A nrPDB 216 1e-56 3CO4-A nrPDB 186 2e-47 3CZ8-A nrPDB 167 6e-42 4WIW-A nrPDB 160 8e-40 4S3K-A nrPDB 159 2e-39 4Q6T-A nrPDB 152 2e-37 4S3J-A nrPDB 149 2e-36 Sequences not found previously or not previously below threshold: 5JH8-A nrPDB 105 3e-23 3BXW-B nrPDB 76 2e-14 3EBV-A nrPDB 59 5e-09 4TX8-A nrPDB 56 3e-08 4RL3-A nrPDB 54 1e-07 3IAN-A nrPDB 52 3e-07 1NAR-A nrPDB 52 4e-07 3N18-A nrPDB 51 7e-07 4AXN-A nrPDB 49 3e-06 3SIM-A nrPDB 48 6e-06 1EDT-A nrPDB 44 1e-04 2Y8V-A nrPDB 43 1e-04 4W5Z-A nrPDB 43 2e-04 4MB4-A nrPDB 41 8e-04 6MDV-A nrPDB 40 0.002 2EBN-A nrPDB 39 0.003 2GSJ-A nrPDB 35 0.041 1F8Q-A nrPDB 34 0.085 4GUW-A nrPDB 34 0.11 4NUY-A nrPDB 34 0.13 3MU7-A nrPDB 33 0.15 4TOQ-A nrPDB 33 0.18 2BHU-A nrPDB 33 0.28 3ZR5-A nrPDB 32 0.39 1CEO-A nrPDB 32 0.58 5KEG-A nrPDB 31 0.70 4TXE-A nrPDB 30 1.4 2XVP-A nrPDB 30 1.4 6MSO-A nrPDB 30 1.5 3HDH-A nrPDB 30 1.8 4HNS-A nrPDB 30 2.0 6Q64-A nrPDB 30 2.1 3V6B-R nrPDB 30 2.1 3V2A-R nrPDB 30 2.1 3S35-X nrPDB 30 2.1 2X1X-R nrPDB 30 2.1 4WP0-A nrPDB 30 2.3 3FVS-A nrPDB 30 2.3 1LFW-A nrPDB 29 2.9 5OT1-A nrPDB 29 3.1 3ML1-A nrPDB 29 3.2 2NYA-A nrPDB 29 3.3 6IBP-A nrPDB 29 3.6 3K4O-A nrPDB 29 4.0 5E9A-A nrPDB 29 4.1 4AEF-A nrPDB 28 5.9 6IDN-A nrPDB 28 6.9 1KQY-A nrPDB 28 7.0 4J3X-A nrPDB 28 7.4 >3AQU-A nrPDB Length = 356 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 355/355 (100%), Positives = 355/355 (100%) Query: 25 QTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ 84 QTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ Sbjct: 2 QTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ 61 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 144 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS Sbjct: 62 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 121 Query: 145 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN 204 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN Sbjct: 122 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN 181 Query: 205 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR 264 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR Sbjct: 182 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR 241 Query: 265 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 324 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY Sbjct: 242 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 301 Query: 325 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV 379 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV Sbjct: 302 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV 356 >1WB0-A nrPDB Length = 445 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 124/372 (33%), Positives = 185/372 (49%), Gaps = 25/372 (6%) Query: 24 AQTVVKASYW----FPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTF 79 A+ V + W + F D+D SL THL AFA + + Q++ + N Sbjct: 1 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH--QLSTTEWNDETLYQE 58 Query: 80 TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDW 139 +++ NP +KTLL+IGG + M + +R++F++S+IR R Y F GLDLDW Sbjct: 59 FNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDW 118 Query: 140 EYPSSAT----EMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 EYP S + F TL+++ +A EA +SGK RLLL+AAV Y Y V Sbjct: 119 EYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDK 178 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSN-----AGPSGDAGTRSWIQAGLPAK 250 +A +LD+VNLMAYDF+G W +VTG + L+ A + DA + W+Q G PA Sbjct: 179 IAQNLDFVNLMAYDFHG-SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPAS 237 Query: 251 KAVLGFPYYGYAWRLTNANSHSYYAPTTGAAIS-----PDGSIGYGQIRKFIVDNGATTV 305 K +LG P YG ++ L +++ AP TG+ G + Y ++ + GAT Sbjct: 238 KLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW---KGATKQ 294 Query: 306 YNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 Y + W+G+DD +S TKV Y KQ+GL G W + DD +G S + Sbjct: 295 RIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGR- 353 Query: 366 WDATTATTRTIQ 377 + + + Sbjct: 354 YPLIQTLRQELS 365 >3RM8-A nrPDB Length = 395 Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats. Identities = 113/371 (30%), Positives = 172/371 (46%), Gaps = 23/371 (6%) Query: 24 AQTVVKASYWFPA----SEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTF 79 Q + W F DI+ L THL AFA + Q N++T N Sbjct: 1 YQLTCYFTNWAQYRPGLGRFMPDDINPCLCTHLIYAFAGM--QNNEITTIEWNDVTLYQA 58 Query: 80 TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDW 139 ++ +N +KTLL+IGG + +M S P +R++FI S I+ R Y F GLD DW Sbjct: 59 FNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDW 118 Query: 140 EYPSS----ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 EYP S + F L++E R A EA KPRL++ AAV + Y + Sbjct: 119 EYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQ 178 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALFD-----PSNAGPSGDAGTRSWIQAGLPAK 250 ++ LD++++M YD +G W TG + L+ SNA + D W G PA+ Sbjct: 179 LSQYLDYIHVMTYDLHG-SWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAE 237 Query: 251 KAVLGFPYYGYAWRLTNANSHSYYAPTTGAAI-----SPDGSIGYGQIRKFIVDNGATTV 305 K ++GFP YG+ + L+N ++ APT+GA G Y +I F+ NGAT Sbjct: 238 KLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFL-KNGATQG 296 Query: 306 YNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 +++ Y Y G W+GYD+ +S K ++ K G W + DD +G + Sbjct: 297 WDAPQEVPYAYQGNVWVGYDNVKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGK- 355 Query: 366 WDATTATTRTI 376 + + + + Sbjct: 356 FPLISTLKKAL 366 >4WKA-A nrPDB Length = 377 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 125/374 (33%), Positives = 186/374 (49%), Gaps = 25/374 (6%) Query: 24 AQTVVKASYW----FPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTF 79 A+ V + W + F D+D SL THL AFA + + Q++ + N Sbjct: 1 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH--QLSTTEWNDETLYQE 58 Query: 80 TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDW 139 +++ NP +KTLL+IGG + M + +R++F++S+IR R Y F GLDLDW Sbjct: 59 FNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDW 118 Query: 140 EYPSSAT----EMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 EYP S + F TL+++ +A EA +SGK RLLL+AAV Y Y V Sbjct: 119 EYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDK 178 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSN-----AGPSGDAGTRSWIQAGLPAK 250 +A +LD+VNLMAYDF+G W +VTG + L+ A + DA + W+Q G PA Sbjct: 179 IAQNLDFVNLMAYDFHG-SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPAS 237 Query: 251 KAVLGFPYYGYAWRLTNANSHSYYAPTTGAAIS-----PDGSIGYGQIRKFIVDNGATTV 305 K +LG P YG ++ L +++ AP TG+ G + Y ++ + GAT Sbjct: 238 KLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW---KGATKQ 294 Query: 306 YNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 Y + W+G+DD +S TKV Y KQ+GL G W + DD +G S + Sbjct: 295 RIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGR- 353 Query: 366 WDATTATTRTIQKV 379 + + + V Sbjct: 354 YPLIQTLRQELSLV 367 >5WV8-A nrPDB Length = 482 Score = 390 bits (1002), Expect = e-109, Method: Composition-based stats. Identities = 118/376 (31%), Positives = 176/376 (46%), Gaps = 24/376 (6%) Query: 24 AQTVVKASYWFPAS----EFPVTDIDSSLFTHLFCAFADLNS------QTNQVTVSSANQ 73 + V + W +F DI L TH+ AF L ++N T + Sbjct: 93 YKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDG--K 150 Query: 74 PKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFH 133 +++ NP +KTLL+IGG + M++ +R++FI S+I R F Sbjct: 151 TGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFD 210 Query: 134 GLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV 193 GLD+DW YP + N+ LL+E R A AEA KPRLLL AAV + Y V Sbjct: 211 GLDIDWLYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDV 270 Query: 194 SAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSWIQAGLP 248 AVAS LD++NLMAYDF+G W R TG A L+ PS+ S D W++ G P Sbjct: 271 PAVASYLDFINLMAYDFHGK-WERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAP 329 Query: 249 AKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGAT 303 +K ++G P YG + L+N N+ +P +G G + Y ++ + + + GA Sbjct: 330 KEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGA- 388 Query: 304 TVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAAS 363 V++ + Y G W+G+DD +SI K+R+ K G W V DD SG + Sbjct: 389 YVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGN 448 Query: 364 QAWDATTATTRTIQKV 379 + A ++ + Sbjct: 449 VKYPLIGAMREELRGI 464 >5WUS-A nrPDB Length = 460 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 112/367 (30%), Positives = 178/367 (48%), Gaps = 19/367 (5%) Query: 25 QTVVKASYWFP----ASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFT 80 Q + + W A F ++D +L TH+ AFA L ++T + Sbjct: 3 QVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDH--KLTEADEKDADMYDKV 60 Query: 81 QTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWE 140 ++ +NP++K LL+IGG T + + SN F+ +I R Y F+GLD+DWE Sbjct: 61 VALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWE 120 Query: 141 YPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 YP A + F +LL+E R A EA +SG+PRLLL AAV S + Y V ++ L Sbjct: 121 YPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYL 180 Query: 201 DWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSWIQAGLPAKKAVLG 255 D++N+M YDF+G W R G + LF +A + D R W++ G P +K ++G Sbjct: 181 DFINVMTYDFHG-QWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIG 239 Query: 256 FPYYGYAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTV 310 P YG ++ L N AP +G + G + Y +I +F+ ++ T V+++ Sbjct: 240 MPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQ 299 Query: 311 VGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATT 370 + + Y W+G+DD +S+ TK+ + K+ G G W V DD G + T Sbjct: 300 MVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGK--YPLIT 357 Query: 371 ATTRTIQ 377 A + + Sbjct: 358 AMKQELS 364 >5XEP-A nrPDB Length = 381 Score = 389 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 106/378 (28%), Positives = 173/378 (45%), Gaps = 22/378 (5%) Query: 14 TFFLTLQCSMAQTVVKASYWFPASE----FPVTDIDSSLFTHLFCAFADLNSQTNQVTVS 69 L CS + V + W E F I L TH+ +FA+++S N ++ Sbjct: 12 VLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSD-NMLSTW 70 Query: 70 SANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARS 129 N ++ RN ++KTLLS+GG ++ +ASN R +F+ S RS Sbjct: 71 EWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGGKRFSEIASNTERRTAFVRSVAPFLRS 130 Query: 130 YGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSV 189 YGF GLDL W YP + F TL++E + E G+ +LLL+AA+ Sbjct: 131 YGFDGLDLAWLYPR-LRDKQYFSTLIKELNAEFTKEV-QPGREKLLLSAALSAGKVAIDT 188 Query: 190 LYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPS-----NAGPSGDAGTRSWIQ 244 Y ++ +A LD++NLM YDF+G W ++TG + LF + + + + I+ Sbjct: 189 GYDIAQIAQHLDFINLMTYDFHGV-WRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIR 247 Query: 245 AGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVD 299 G A K ++G P +G ++ L ++ + AP +G G++ Y +I F+ Sbjct: 248 LGAQASKLLMGIPTFGKSFTLASSEN-QLGAPISGEGLPGRFTKEAGTLAYYEICDFL-- 304 Query: 300 NGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 GA S + G W+GY+D +S+ KVR+ K++ L G W + DD G + Sbjct: 305 KGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVRFLKEKKLAGAMVWALDLDDFQG-T 363 Query: 360 RAASQAWDATTATTRTIQ 377 + + T A + Sbjct: 364 CQPKEFFPLTNAIKDALA 381 >1HJW-A nrPDB Length = 362 Score = 384 bits (986), Expect = e-107, Method: Composition-based stats. Identities = 105/368 (28%), Positives = 171/368 (46%), Gaps = 22/368 (5%) Query: 24 AQTVVKASYWFPASE----FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTF 79 + V + W E +D L TH+ +FA++++ + N Sbjct: 1 YKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISND--HIDTWEWNDVTLYGM 58 Query: 80 TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDW 139 T++ RNP++KTLLS+GG ++ +ASN SR++FI S R++GF GLDL W Sbjct: 59 LNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAW 118 Query: 140 EYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASS 199 YP + +F TL++E ++ + E + GK +LLL+AA+ Y ++ ++ Sbjct: 119 LYPGR-RDKQHFTTLIKEMKAEFIKE-AQPGKKQLLLSAALSAGKVTIDSSYDIAKISQH 176 Query: 200 LDWVNLMAYDFYGPGWSRVTGPPAALFDP-----SNAGPSGDAGTRSWIQAGLPAKKAVL 254 LD++++M YDF+G W TG + LF + + D ++ G PA K V+ Sbjct: 177 LDFISIMTYDFHG-AWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVM 235 Query: 255 GFPYYGYAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNST 309 G P +G ++ L + + AP +G G++ Y +I F+ GAT Sbjct: 236 GIPTFGRSFTLAS-SETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLR--GATVHRILG 292 Query: 310 VVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDAT 369 Y G W+GYDD +S+ +KV+Y K R L G W + DD G + T Sbjct: 293 QQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLT 352 Query: 370 TATTRTIQ 377 A + Sbjct: 353 NAIKDALA 360 >3ALF-A nrPDB Length = 353 Score = 384 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 210/343 (61%), Positives = 243/343 (70%), Gaps = 5/343 (1%) Query: 28 VKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRN 87 VK YWF S + +IDS+LFTHLFCAFADLN Q NQ+ +S NQ F FT TVQR+N Sbjct: 4 VKGGYWFKDSGLALNNIDSTLFTHLFCAFADLNPQLNQLIISPENQDSFRQFTSTVQRKN 63 Query: 88 PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATE 147 PSVKT LSI GG A+ TAY MA P SRKSFIDSSIR+AR GFHGLDLDWEYP SA + Sbjct: 64 PSVKTFLSIAGGRANSTAYGIMARQPNSRKSFIDSSIRLARQLGFHGLDLDWEYPLSAAD 123 Query: 148 MTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMA 207 MTN GTLL EWR+A+ EA +SG+ LLL AAV S + YPV ++A +LDW+NLMA Sbjct: 124 MTNLGTLLNEWRTAINTEARNSGRAALLLTAAVSNSPRVNGLNYPVESLARNLDWINLMA 183 Query: 208 YDFYGPGWSR-VTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLT 266 YDFYGP WS T A LFDP N SG G +WIQAG+P KK VLG P+YGYAWRL Sbjct: 184 YDFYGPNWSPSQTNSHAQLFDPVN-HVSGSDGINAWIQAGVPTKKLVLGIPFYGYAWRLV 242 Query: 267 NANSHSYYAPTTGA---AISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIG 323 NAN H AP G DGS+ Y +IR +IV++ ATTVYN+T+VGDYCY+G+NWI Sbjct: 243 NANIHGLRAPAAGKSNVGAVDDGSMTYNRIRDYIVESRATTVYNATIVGDYCYSGSNWIS 302 Query: 324 YDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 YDD Q++ KV Y K RGLLGYF+WHV D N GLSR ASQ W Sbjct: 303 YDDTQTVRNKVNYVKGRGLLGYFAWHVAGDQNWGLSRTASQTW 345 >2QF8-A nrPDB Length = 361 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 107/369 (28%), Positives = 176/369 (47%), Gaps = 21/369 (5%) Query: 24 AQTVVKASYWFPASE----FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTF 79 + + + W E ID L TH+ +FA++++ N++ N Sbjct: 1 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISN--NEIDTWEWNDVTLYDT 58 Query: 80 TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDW 139 T++ RNP++KTLLS+GG ++ +AS SR++FI S R++GF GLDL W Sbjct: 59 LNTLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAW 118 Query: 140 EYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASS 199 +P + + TL++E ++ V E + +G +LLL+AAV Y ++ ++ Sbjct: 119 LWPG-WRDKRHLTTLVKEMKAEFVRE-AQAGTEQLLLSAAVTAGKIAIDRGYDIAQISRH 176 Query: 200 LDWVNLMAYDFYGPGWSRVTGPPAALF----DPSNAGPSGDAGTRSWIQAGLPAKKAVLG 255 LD+++L+ YDF+G W + G + LF D S+ + D ++ G PA K V+G Sbjct: 177 LDFISLLTYDFHG-AWRQTVGHHSPLFRGNEDASSRFSNADYAVSYMLRLGAPANKLVMG 235 Query: 256 FPYYGYAWRLTNANSHSYYAPTTGAAISP-----DGSIGYGQIRKFIVDNGATTVYNSTV 310 P +G ++ L + + AP +G I G + Y +I F+ +GATT Sbjct: 236 IPTFGRSYTLAS-SKTDVGAPISGPGIPGRFTKWKGILAYYEICDFL--HGATTHRFRDQ 292 Query: 311 VGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATT 370 Y G W+ YDD +S+ K RY K R L G W + DD G + + T+ Sbjct: 293 QVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTS 352 Query: 371 ATTRTIQKV 379 A + +V Sbjct: 353 AIKDVLARV 361 >1E9L-A nrPDB Length = 377 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 107/368 (29%), Positives = 168/368 (45%), Gaps = 23/368 (6%) Query: 24 AQTVVKASYWFP----ASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTF 79 Q + + W F +ID L THL AFA + Q N++T + + Sbjct: 1 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEA 58 Query: 80 TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDW 139 ++ +N +KTLL+IGG +++M S P +R+ FI S IR R Y F GL+LDW Sbjct: 59 LNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDW 118 Query: 140 EYPSS----ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 +YP S + F L++E R A E+ PRLLL + + Y + Sbjct: 119 QYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPE 178 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALF-DPSNAGPSGDAGTR----SWIQAGLPAK 250 ++ SLD++ +M YD + P TG + L+ P + G S D W G ++ Sbjct: 179 LSQSLDYIQVMTYDLHDPK-DGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASE 237 Query: 251 KAVLGFPYYGYAWRLTNANSHSYYAPT-----TGAAISPDGSIGYGQIRKFIVDNGATTV 305 K ++GFP YG+ + L++ + APT G G + Y ++ F+ + GAT V Sbjct: 238 KLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFL-NEGATEV 296 Query: 306 YNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 +++ Y Y G W+GYD+ +S K ++ K L G W + DD SG Sbjct: 297 WDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRH- 355 Query: 366 WDATTATT 373 + T+ Sbjct: 356 FPLTSTLK 363 >4MNK-A nrPDB Length = 348 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 157/349 (44%), Positives = 218/349 (62%), Gaps = 11/349 (3%) Query: 25 QTVVKASYW--FPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQT 82 Q +K +W + SEFP + I+S LFTHL+ AFA+LN+ T +V V ++ FT T Sbjct: 2 QNALKVGFWPAYSVSEFPPSKINSRLFTHLYYAFAELNAPTFEVRVPPGSEKTAEDFTPT 61 Query: 83 VQRRNPSVKTLLSIGGGIAD-KTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEY 141 V+R NPSVKTL+SIGGG ++ + +A + S+ ++R+ F+ SSI +AR YGFHGLDLD+EY Sbjct: 62 VRRLNPSVKTLISIGGGGSEVRDNFAKLNSDASARQRFVKSSIALARRYGFHGLDLDYEY 121 Query: 142 PSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSV----LYPVSAVA 197 P EM NF L+ E +A+ EA +SGKPRLLL AV++ + YPV +A Sbjct: 122 PEPQLEMENFVKLVSELTAAIREEARTSGKPRLLLTEAVYFHQKLFPWEVVTEYPVQFIA 181 Query: 198 SSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFP 257 + LDWVN+MAYDF+G W TG PAAL DP N+ + G S++ AG+P +K VLG P Sbjct: 182 AGLDWVNVMAYDFHG-SWENFTGAPAALRDP-NSKFTASVGIESFLAAGMPPEKLVLGIP 239 Query: 258 YYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYA 317 +G +W L N N AP GA DG++ + +I+ FI GA V+++T V Y Y Sbjct: 240 LFGRSWLLKNNNEVGIGAPAVGAG-PVDGALSFSEIQNFI-RGGAREVFDTTTVSAYAYK 297 Query: 318 GTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 W+GYD+ QS+ KV+YAK++ L GYF W V D ++ L + AS W Sbjct: 298 DNVWVGYDNQQSVALKVQYAKEKRLGGYFFWSVNQDIDAILPKIASDTW 346 >4P8U-A nrPDB Length = 371 Score = 358 bits (920), Expect = 1e-99, Method: Composition-based stats. Identities = 106/370 (28%), Positives = 173/370 (46%), Gaps = 24/370 (6%) Query: 23 MAQTVVKASYWFPA----SEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFST 78 + V + W +F +ID L +HL +FA + + N+V + ++ Sbjct: 7 SYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASI--ENNKVIIKDKSEVMLYQ 64 Query: 79 FTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLD 138 +++ +NP +K LLSIGG + + M + TSR FI+S I R++ F GLD+ Sbjct: 65 TINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVS 124 Query: 139 WEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVAS 198 W YP E T+F L+ E A + + S K RLLL V Y V +A Sbjct: 125 WIYPDQK-ENTHFTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVEKLAK 183 Query: 199 SLDWVNLMAYDFYGPGWSR--VTGPPAALFD-----PSNAGPSGDAGTRSWIQAGLPAKK 251 LD++NL+++DF+G W + +TG + L ++ + + WI G+P++K Sbjct: 184 DLDFINLLSFDFHG-SWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEK 242 Query: 252 AVLGFPYYGYAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVY 306 V+G P YG+++ L +A + AP +G G + Y +I +F+ GA + Sbjct: 243 VVMGIPTYGHSFTLASAETT-VGAPASGPGAAGPITESSGFLAYYEICQFL--KGAKITW 299 Query: 307 NSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 Y G W+GYDD +S+ TKV++ K L G W + DD +G S + Sbjct: 300 LQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQG-PY 358 Query: 367 DATTATTRTI 376 A R++ Sbjct: 359 PLVQAVKRSL 368 >5Y29-A nrPDB Length = 377 Score = 341 bits (874), Expect = 4e-94, Method: Composition-based stats. Identities = 100/371 (26%), Positives = 162/371 (43%), Gaps = 19/371 (5%) Query: 22 SMAQTVVKASYWFPAS----EFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFS 77 S + V + W ++ DID SL TH+ FA L + + + Sbjct: 5 SRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNR 64 Query: 78 TFTQTVQRRNPSVKTLLSIGGGIADKT-AYASMASNPTSRKSFIDSSIRVARSYGFHGLD 136 + + V+ + +K L++GG Y+ + ++P +R F+ ++ YGF GLD Sbjct: 65 FYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLD 124 Query: 137 LDWEYPSSAT-EMTNFGTLLREWRSAVVAEASSSGKPR-LLLAAAVFYSNNYYSVLYPVS 194 LDWEYP + + ++ + +V E S+ KP+ LLL+AAV + Y V Sbjct: 125 LDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVP 184 Query: 195 AVASSLDWVNLMAYDFYGPGWSRVTGPPAALF---DPSNAGPSGDAGTRSWIQAGLPAKK 251 +A LDW+ +M YD++G W + TG A L+ D + + W++ G PA K Sbjct: 185 VLARLLDWIAVMTYDYHG-QWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASK 243 Query: 252 AVLGFPYYGYAWRLTNANSHSYYAPTT-----GAAISPDGSIGYGQIRKFIVDNGATTVY 306 V+G P YG ++ + N H P + G G + Y +I I ++G T V Sbjct: 244 IVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVK 303 Query: 307 NS-TVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 + +G Y Y G W+ +DD + I KV + K L G W + DD +R Sbjct: 304 DPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYR--NRCGQGK 361 Query: 366 WDATTATTRTI 376 A + Sbjct: 362 HPLLNAIKTEL 372 >6G9C-A nrPDB Length = 495 Score = 339 bits (869), Expect = 1e-93, Method: Composition-based stats. Identities = 99/368 (26%), Positives = 157/368 (42%), Gaps = 25/368 (6%) Query: 28 VKASYWFPA----SEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTV 83 + W ++ ++L ++F AFA LN TV V Sbjct: 37 CYFTNWAQYRPGNGKYNPEHYQANLCEYIFYAFAKLND---DFTVDQFEWNDIDVLYPGV 93 Query: 84 QRR---NPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWE 140 ++ P +K LLS+GG A + MA+ ++R FI S + + F G DLDWE Sbjct: 94 MKQKSSQPDLKVLLSLGGWNAGTATFKKMAATYSNRAKFISSLVSFLQQNKFDGFDLDWE 153 Query: 141 YPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 YP S ++ N+ L +E + A + RLL AAV + Y V A+A L Sbjct: 154 YPES-SDKENYLLLCQEILAKFEEVAKCTSTSRLLFTAAVSANPKTVDAGYDVPALAKVL 212 Query: 201 DWVNLMAYDFYGPGWSRVTGPPAALFDPSNAG-----PSGDAGTRSWIQAGLPAKKAVLG 255 D+VNLM YDF+G W TG + L+ + + ++ W G+P K+ ++G Sbjct: 213 DFVNLMCYDFHG-AWETQTGINSPLYSRKEDSSEFKMWNVEQSSKYWSDKGMPKKQIIIG 271 Query: 256 FPYYGYAWRLTNANSHSYYAPTTGAAIS-----PDGSIGYGQIRKFIVDNGATTVYNSTV 310 P YG W L++A+ AP G++ + G I Y ++ + + +GA V++ Sbjct: 272 LPTYGRGWTLSDASKTDIGAPAQGSSTATEYLREAGVISYYEVCQKL-SSGAKRVWDDES 330 Query: 311 VGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA--WDA 368 Y G W YDD +S+ K+ + KQ G F W + DD G + Sbjct: 331 KTPYLVQGNQWFSYDDVESMKAKINWIKQENYGGAFVWTLDYDDFLGSFCTEHNGKKYPL 390 Query: 369 TTATTRTI 376 + + Sbjct: 391 ISLMQEIL 398 >4URI-A nrPDB Length = 337 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 180/344 (52%), Positives = 229/344 (66%), Gaps = 13/344 (3%) Query: 27 VVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRR 86 +K YW+ S V+DI+ S FTHLFCAFADL+ TN++T+SS+N FSTFTQTV+ + Sbjct: 1 AIKGGYWYSGSGLAVSDINPSHFTHLFCAFADLDPNTNKLTISSSNAAAFSTFTQTVRAK 60 Query: 87 NPSVKTLLSIGGGI--ADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS 144 NPSVKTLLSIGGG A +A+MAS + RKSFIDSSI++AR FHGLDLDWEYPSS Sbjct: 61 NPSVKTLLSIGGGGGRALAAVFANMASQASRRKSFIDSSIQLARRNNFHGLDLDWEYPSS 120 Query: 145 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYS-VLYPVSAVASSLDWV 203 + TNF +L+REWR+AV E+S+SG P LLL+AAV S+ YP A+A++LDWV Sbjct: 121 DIDKTNFASLIREWRAAVATESSTSGTPALLLSAAVGGSDQITPLKYYPGEAIANNLDWV 180 Query: 204 NLMAYDFYGP-GWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYA 262 N+M YD Y + +T PPA LF P S D G WIQ+G+P K LG P+YG+ Sbjct: 181 NVMTYDLYTSDSYPTLTQPPAPLFYPRGIF-SADEGITKWIQSGVPESKLALGLPFYGFK 239 Query: 263 WRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWI 322 WRL++ N+H +AP T G++ Y I V+ G ++ST V +Y + GT+W Sbjct: 240 WRLSDPNNHGLFAPATQG----LGAVKYKDI----VNTGGQVEFDSTYVTNYRFKGTDWY 291 Query: 323 GYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 GYDD QSI KV YAKQRGL GYF+WH+ D N LS AS+AW Sbjct: 292 GYDDTQSISAKVAYAKQRGLFGYFAWHIEQDSNWALSETASRAW 335 >3W4R-A nrPDB Length = 554 Score = 333 bits (854), Expect = 6e-92, Method: Composition-based stats. Identities = 95/367 (25%), Positives = 162/367 (44%), Gaps = 37/367 (10%) Query: 22 SMAQTVVKASYWF----PASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSS----ANQ 73 S A+ V S W + + DI + TH+ +F + T QV + ++ Sbjct: 23 SRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDK 82 Query: 74 PKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFH 133 F FT +++ ++P VK +++GG + Y+ M + ++R +F+ S + Y F Sbjct: 83 NGFKNFT-SLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFD 141 Query: 134 GLDLDWEYPSSAT------EMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYY 187 GLDLDWEYP +A + F L++E R A + E L AAV +N Sbjct: 142 GLDLDWEYPGAADRGGSFSDKDKFLYLVQELRRAFIREG-----KGWELTAAVPLANFRL 196 Query: 188 SVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSW 242 Y V + LD +++M+YD G W+ + L+ + + + G + W Sbjct: 197 MEGYHVPELCQELDAIHVMSYDLRG-NWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLW 255 Query: 243 IQAGLPAKKAVLGFPYYGYAWRLTNANSH---------SYYAPTTGAAISPDGSIGYGQI 293 G P K V+G P+YG ++ L++ N++ + G Y +I Sbjct: 256 EDKGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYEI 315 Query: 294 RK--FIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVG 351 D+ T ++ Y Y GT W+GY+D +S+ K+ + K++G LG +W + Sbjct: 316 CTEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAID 375 Query: 352 ADDNSGL 358 DD GL Sbjct: 376 MDDFQGL 382 >3WKZ-A nrPDB Length = 395 Score = 324 bits (830), Expect = 5e-89, Method: Composition-based stats. Identities = 94/367 (25%), Positives = 162/367 (44%), Gaps = 37/367 (10%) Query: 22 SMAQTVVKASYWF----PASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSS----ANQ 73 S A+ V S W + + DI + TH+ +F + T QV + ++ Sbjct: 5 SRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDK 64 Query: 74 PKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFH 133 F FT +++ ++P VK +++GG + Y+ M + ++R +F+ S + Y F Sbjct: 65 NGFKNFT-SLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFD 123 Query: 134 GLDLDWEYPSSAT------EMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYY 187 GLDLDW+YP +A + F L++E R A + E L AAV +N Sbjct: 124 GLDLDWQYPGAADRGGSFSDKDKFLYLVQELRRAFIREG-----KGWELTAAVPLANFRL 178 Query: 188 SVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSW 242 Y V + LD +++M+YD G W+ + L+ + + + G + W Sbjct: 179 MEGYHVPELCQELDAIHVMSYDLRG-NWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLW 237 Query: 243 IQAGLPAKKAVLGFPYYGYAWRLTNANSH---------SYYAPTTGAAISPDGSIGYGQI 293 G P K V+G P+YG ++ L++ N++ + G Y +I Sbjct: 238 EDKGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYEI 297 Query: 294 RK--FIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVG 351 D+ T ++ Y Y GT W+GY+D +S+ K+ + K++G LG +W + Sbjct: 298 CTEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAID 357 Query: 352 ADDNSGL 358 DD GL Sbjct: 358 MDDFQGL 364 >5Y2C-A nrPDB Length = 383 Score = 320 bits (820), Expect = 7e-88, Method: Composition-based stats. Identities = 90/378 (23%), Positives = 158/378 (41%), Gaps = 33/378 (8%) Query: 24 AQTVVKASYWFPAS----EFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSS-ANQPKFST 78 + V + W ++ DI+ L TH+ AFA L+ + + + Sbjct: 3 FKVVCYYTNWAWYRPDNGKYTPGDINPELCTHIIYAFAVLDKEELVIKSHDIWLDVENKF 62 Query: 79 FTQTVQRRNPSVKTLLSIGGGIADKT-AYASMASNPTSRKSFIDSSIRVARSYGFHGLDL 137 + + ++ VK LL +GG Y+ + +N ++R+ F+ ++ YGF GLDL Sbjct: 63 YEKVTALKSHGVKVLLGLGGWDDSAGDKYSRLVNNVSARRKFVVHAVDFLEQYGFDGLDL 122 Query: 138 DWEYPSSA---------TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYS 188 DW YP ++ F L++E R A + +LL+AAV S Sbjct: 123 DWLYPKCWQVECEKGPDSDKQGFADLVKELRKAF-------NRRGMLLSAAVSASKRVID 175 Query: 189 VLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALF---DPSNAGPSGDAGTRSWIQA 245 Y V A++ +LDW++LM YD++G W + TG A ++ ++ + + WI Sbjct: 176 YAYNVPALSMNLDWISLMTYDYHG-QWDKKTGHVAPMYVHDKDTDNTFNVNFTVNYWINK 234 Query: 246 GLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPD-----GSIGYGQIRKFIVDN 300 G KK V+G P+YG ++ + APT + D G + + +I + + Sbjct: 235 GADRKKLVVGVPFYGQSFSVVEGAGTGLGAPTYAGGEAGDETRARGFLSFYEICERVKVK 294 Query: 301 GATTVYNST-VVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 359 G + +G Y W+ +DD+ K Y + L G +W + DD +G Sbjct: 295 GWKVHRDPGGRIGPYATHDDQWVSFDDDFMARHKAEYVRAMELGGSMAWSLDLDDFTGKY 354 Query: 360 RAASQAWDATTATTRTIQ 377 +A T ++ Sbjct: 355 CGCGKA-PLLTTINHVLR 371 >1ITX-A nrPDB Length = 419 Score = 311 bits (797), Expect = 3e-85, Method: Composition-based stats. Identities = 108/407 (26%), Positives = 173/407 (42%), Gaps = 73/407 (17%) Query: 23 MAQTVVKASYWFPASE-FPVTDIDSSLFTHLFCAFADL---------------------- 59 + V W + V DID + TH+ AFAD+ Sbjct: 11 SYKIVGYYPSWAAYGRNYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGPNPVTWTCQ 70 Query: 60 NSQTNQVTVSS--------------------ANQPKFSTFTQT--VQRRNPSVKTLLSIG 97 N ++ + V + +QP Q +++ NP++KT++S+G Sbjct: 71 NEKSQTINVPNGTIVLGDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPNLKTIISVG 130 Query: 98 GGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS---------ATEM 148 G ++ +A+ +R+ F +S++ R Y F G+DLDWEYP S + Sbjct: 131 GWTW-SNRFSDVAATAATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDGNSKRPEDK 189 Query: 149 TNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAY 208 N+ LL + R + A + GK LL A+ + Y+ ++ +A+ +DW+N+M Y Sbjct: 190 QNYTLLLSKIREKLDAAGAVDGKKYLLTIASGASA--TYAANTELAKIAAIVDWINIMTY 247 Query: 209 DFYGPGWSRVTGPPAAL-FDPSNAGP--------SGDAGTRSWIQAGLPAKKAVLGFPYY 259 DF G W +++ A L +DP+ + + AG + + AG+PA K VLG P+Y Sbjct: 248 DFNG-AWQKISAHNAPLNYDPAASAAGVPDANTFNVAAGAQGHLDAGVPAAKLVLGVPFY 306 Query: 260 GYAWRLTNANSHSYYAPTTGA---AISPDGSIGYGQIR-KFIVDNGATTVYNSTVVGDYC 315 G W + Y TG GS + + +I NG T +N T Y Sbjct: 307 GRGWDGCAQAGNGQYQTCTGGSSVGTWEAGSFDFYDLEANYINKNGYTRYWNDTAKVPYL 366 Query: 316 YAGTN--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSR 360 Y +N +I YDD +S+ K Y K +GL G W + D N L Sbjct: 367 YNASNKRFISYDDAESVGYKTAYIKSKGLGGAMFWELSGDRNKTLQN 413 >5GZU-A nrPDB Length = 885 Score = 306 bits (784), Expect = 9e-84, Method: Composition-based stats. Identities = 93/342 (27%), Positives = 161/342 (47%), Gaps = 35/342 (10%) Query: 44 IDSSLFTHLFCAFADLNSQ-----------TNQVTVSSANQPKFST--------FTQTVQ 84 +D++ FTHL+ AF +N+ T T++ A++ K + ++ Sbjct: 45 VDATKFTHLYYAFGRINNGKVVTIKEDAKWTEDPTITEADRIKRRNNPDESNLAYLTGLK 104 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP-- 142 +NP++K L+SIGG + ++ A P SR+ F +S++ Y G+DLDWEYP Sbjct: 105 AKNPNLKVLVSIGGW--EAEGFSDAALTPESREVFANSALDFMNKYNLDGIDLDWEYPVY 162 Query: 143 -------SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 S + NF LL+ R + A+++++ K L AA + Y+ ++ Sbjct: 163 GAWGVIKSRPEDKANFTALLKLLREKLDAQSTTTNKYYELAIAAGA--SKTYTDSVELTK 220 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLG 255 + LD++NLM YD +G GW T A++ +N S D+ + ++ G+PA+K ++G Sbjct: 221 ITPYLDYINLMTYDLHG-GWDPATSHHTAVYSATNNQLSVDSTVKLYLNNGVPAEKLMVG 279 Query: 256 FPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQ-IRKFIVDNGATTVYNSTVVGDY 314 +Y W+ + G+ G+I Y + + +I NG T ++ T Y Sbjct: 280 GAFYSRVWQNVENKGTGL-SEKAGSQAGSPGTIVYSELVNNYINKNGYTRYWDDTAKAPY 338 Query: 315 CYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNS 356 + G+ +I Y+D S K Y KQ L G+ W D +S Sbjct: 339 LFNGSTFISYEDTASAAYKAEYIKQNNLAGFMYWEYSQDSDS 380 Score = 281 bits (718), Expect = 4e-76, Method: Composition-based stats. Identities = 96/352 (27%), Positives = 158/352 (44%), Gaps = 39/352 (11%) Query: 43 DIDSSLFTHLFCAFADLNS----------------QTNQVTVSSANQPKFSTF--TQTVQ 84 +D++ TH+ AFA + + ++ N P + F +T++ Sbjct: 531 KVDATKLTHINYAFARIKDNKVVKISEDINWVNEFPSEEIREQRRNNPDDANFAYLKTLK 590 Query: 85 RRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP-- 142 ++NPS+K L+SIGG A+ ++ A P +R+ +S+I YGF G+DLDWEYP Sbjct: 591 QQNPSLKVLVSIGGWAAE--GFSDAALTPETREELANSAIAFMHQYGFDGIDLDWEYPVY 648 Query: 143 -------SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSA 195 S + NF LL+ +R + E + GK L A+ Y + Sbjct: 649 GAFGVIKSRPEDKQNFTALLKLFREKLDVEGALHGKYYELAIASAAAP--IYINSVELDK 706 Query: 196 VASSLDWVNLMAYDFYGPGWSRVTGPPAALF--DPSNAGPSGDAGTRSWIQAGLPAKKAV 253 + LD++++M YD++G W T A+++ S S D+ ++ + G+PA K V Sbjct: 707 IHQYLDYMSVMTYDYHG-SWESKTAHQASVYTSALSPGDFSADSVLTAYRKQGVPASKLV 765 Query: 254 LGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGD 313 +G +Y W +H + A +P G+ Y + K D G T ++++ Sbjct: 766 IGGAFYARGWVNVPNINHGLFQQAGDQAKNP-GTPTYNDLVKDYFDKGYTRYWDNSAKAP 824 Query: 314 YCY----AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRA 361 Y Y G +I YDD +S+ K YAK +GL G W D + L A Sbjct: 825 YLYNPDANGGTFITYDDEESLKYKAEYAKNQGLRGVMFWDYSQDISGKLLGA 876 >6BT9-A nrPDB Length = 672 Score = 301 bits (772), Expect = 2e-82, Method: Composition-based stats. Identities = 105/415 (25%), Positives = 165/415 (39%), Gaps = 90/415 (21%) Query: 25 QTVVKASYW-FPASEFPVTDIDSSLFTHLFCAFADL-------------NSQTNQVTV-- 68 + V W + V DID+S THL AFAD+ ++ Q Sbjct: 38 KIVGYFPSWGVYGRNYQVADIDASKLTHLNYAFADICWNGKHGNPSTHPDNPNKQTWNCK 97 Query: 69 -------------------SSANQPKF------------------STFTQT--VQRRNPS 89 F + ++ + P Sbjct: 98 ESGVPLQNKEVPNGTLVLGEPWADVTKSYPVSGTTWEDCDKYARCGNFGELKRLKAKYPH 157 Query: 90 VKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPS------ 143 +KT++S+GG ++ MA++ +RK F +S++ R+YGF G+DLDWEYP Sbjct: 158 LKTIISVGGWTW-SNRFSDMAADEKTRKVFAESTVAFLRAYGFDGVDLDWEYPGVETIPG 216 Query: 144 ---SATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 + NF LL++ R+A+ + GK LL A ++ Y+ + ++ L Sbjct: 217 GSYRPEDKQNFTLLLQDVRNALNKAGAEDGKQYLLTIA--SGASQRYADHTELKKISQIL 274 Query: 201 DWVNLMAYDFYGPGWSRVTGPPAALF-DPSNAGPSG----DAGTRSWIQAGLPAKKAVLG 255 DW+N+M YDF+G GW + AAL+ DP++ + D + G+P K VLG Sbjct: 275 DWINIMTYDFHG-GWEATSNHNAALYKDPNDPAANTNFYVDGAINVYTNEGVPVDKLVLG 333 Query: 256 FPYYGYAWRLTNANSHSYYAPTTGA--------------AISPDGSIGYGQI-RKFIVDN 300 P+YG W+ ++ Y P + G YG + ++ N Sbjct: 334 VPFYGRGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVYDYGDLAANYVNKN 393 Query: 301 GATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 G +N T Y Y T +I YDDN+S+ K Y K +GL G W + D Sbjct: 394 GFVRYWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWELSGD 448 >3CHF-A nrPDB Length = 433 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 97/358 (27%), Positives = 162/358 (45%), Gaps = 35/358 (9%) Query: 22 SMAQTVVKASYWF-PASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSS---------- 70 S ++VV W D+ TH+ AFA++ +T +V ++ Sbjct: 41 SGYRSVVYFVNWAIYGRNHNPQDLPVERLTHVLYAFANVRPETGEVYMTDSWADIEKHYP 100 Query: 71 ---ANQPKFSTF-----TQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDS 122 + + + ++++N ++K LLSIGG +A AS RK+F + Sbjct: 101 GDSWSDTGNNVYGCIKQLYLLKKQNRNLKVLLSIGGWTYSPN-FAPAASTDAGRKNFAKT 159 Query: 123 SIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSS-GKPRLLLAAAVF 181 ++++ + GF GLD+DWEYP + + +F LL+E R+A+ + ++++ G LL A Sbjct: 160 AVKLLQDLGFDGLDIDWEYPENDQQANDFVLLLKEVRTALDSYSAANAGGQHFLLTVASP 219 Query: 182 YSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTR- 240 + VL+ + + LD+ NLMAYD+ G +S ++G A +++ ++ S T+ Sbjct: 220 AGPDKIKVLH-LKDMDQQLDFWNLMAYDYAG-SFSSLSGHQANVYNDTSNPLSTPFNTQT 277 Query: 241 ---SWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFI 297 + G+PA K VLG P YG ++ T+ Y G +G Y K + Sbjct: 278 ALDLYRAGGVPANKIVLGMPLYGRSFANTDGPGKPYNG--VGQGSWENGVWDY----KAL 331 Query: 298 VDNGATTVYNSTVVGDYCYAGTN--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 GAT ++ Y Y TN I YD+ Q K Y K GL G W +D Sbjct: 332 PQAGATEHVLPDIMASYSYDATNKFLISYDNPQVANLKSGYIKSLGLGGAMWWDSSSD 389 >5ZL9-A nrPDB Length = 618 Score = 290 bits (742), Expect = 8e-79, Method: Composition-based stats. Identities = 84/388 (21%), Positives = 144/388 (37%), Gaps = 62/388 (15%) Query: 36 ASEFPVTDIDSSLFTHLFCAFADLNS---------------------------------- 61 F V I + THL F + Sbjct: 148 GRNFTVDKIPAQNLTHLLYGFIPICGGNGINDSLKEIEGSFQALQRSCQGREDFKVSIHD 207 Query: 62 -----QTNQVTVSSANQPKFSTFTQT--VQRRNPSVKTLLSIGGGIADKTAYASMASNPT 114 Q Q V++ + P F Q +++ +P +K L SIGG + + Sbjct: 208 PFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFF--FMGDKV 265 Query: 115 SRKSFIDSSIRVARSYGF-HGLDLDWEYPSSATEMTN---------FGTLLREWRSAVVA 164 R F+ S +++ F G+D+DWE+P N + L++E R+ + Sbjct: 266 KRDRFVGSVKEFLQTWKFFDGVDIDWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQ 325 Query: 165 EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAA 224 + +G+ L +A + V+ +S+D + LM+YDFYG + G A Sbjct: 326 LSVETGRKYELTSAISAGKDKIDKFYSFVNVAQNSMDHIFLMSYDFYGAFDLKNLGHQTA 385 Query: 225 LFDP---SNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNA--NSHSYYAPTTG 279 L P + + G + + G+ K V+G YG W N N+ + TG Sbjct: 386 LNAPAWKPDTAYTTVNGVNALLAQGVKPGKIVVGTAMYGRGWTGVNGYQNNIPFTGTATG 445 Query: 280 --AAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVR 335 +G + Y QI + Y++T Y + + + I +DD +S+ K + Sbjct: 446 PVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDARSVQAKGK 505 Query: 336 YAKQRGLLGYFSWHVGADDNSGLSRAAS 363 Y + L G FSW + AD+ L+ + Sbjct: 506 YVLDKQLGGLFSWEIDADNGDILNSMNA 533 >5GQB-A nrPDB Length = 553 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 86/383 (22%), Positives = 144/383 (37%), Gaps = 64/383 (16%) Query: 37 SEFPVTDIDSSLFTHLFCAFADLNS----------------------------------- 61 +FPV + THL F + Sbjct: 165 RKFPVDRVPIPNLTHLLYGFIPICGGDGINDSLKEIEGSFQALQRSCSGREDFKVSIHDP 224 Query: 62 ----QTNQVTVSSANQPKFSTFTQT--VQRRNPSVKTLLSIGGGIADKTAYASMASNPTS 115 Q Q +SS N+P F Q +++ P +K L SIGG + ++ T Sbjct: 225 WAALQKPQKGLSSWNEPYKGNFGQLMMLKQAKPDLKILPSIGGWTLADPFF--FFTDETK 282 Query: 116 RKSFIDSSIRVARSYGF-HGLDLDWEYPSSATEMTN---------FGTLLREWRSAVVAE 165 R+ F+ S +++ F G+D+DWE+P N + L++E R + Sbjct: 283 RRRFVASVKDFLQTWKFFDGVDIDWEFPGGKGANPNLGSPKDGEIYVLLMKELREMLNEL 342 Query: 166 ASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAAL 225 ++ +G+ L +A + V SA +D + M+YDF G + G A+L Sbjct: 343 SAETGRKYELTSAISAGWDKIQVV--DYSAAQKYMDHIFFMSYDFKGAWSNDTLGHQASL 400 Query: 226 FDPS---NAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLT--NANSHSYYAPTTG- 279 + P + D G + + G+ KK V+G YG W +++ + TG Sbjct: 401 YAPDWNEKETYTTDFGVQFLLAQGVSPKKIVVGVAMYGRGWTGVHGYKDNNPFTGNATGP 460 Query: 280 -AAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAG--TNWIGYDDNQSIVTKVRY 336 DG + Y +I I Y+ Y + + I YDD +S + K +Y Sbjct: 461 VKGTWQDGVVDYREIATEIAQGKWEYHYDKVAQAPYVFRPATGDLITYDDARSTIEKGKY 520 Query: 337 AKQRGLLGYFSWHVGADDNSGLS 359 + L G F+W + AD+ L+ Sbjct: 521 VRANKLGGLFAWEIDADNGDILN 543 >5Z7M-A nrPDB Length = 546 Score = 286 bits (732), Expect = 1e-77, Method: Composition-based stats. Identities = 84/388 (21%), Positives = 144/388 (37%), Gaps = 64/388 (16%) Query: 36 ASEFPVTDIDSSLFTHLFCAFADLNS---------------------------------- 61 F V I + THL F + Sbjct: 148 GRNFTVDKIPAQNLTHLLYGFIPICGGNGINDSLKEIEGSFQALQRSCQGREDFKVSIHD 207 Query: 62 -----QTNQVTVSSANQPKFSTFTQT--VQRRNPSVKTLLSIGGGIADKTAYASMASNPT 114 Q Q V++ + P F Q +++ +P +K L SIGG + + Sbjct: 208 PFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFF--FMGDKV 265 Query: 115 SRKSFIDSSIRVARSYGF-HGLDLDWEYPSSATEMTN---------FGTLLREWRSAVVA 164 R F+ S +++ F G+D+ WE+P N + L++E R+ + Sbjct: 266 KRDRFVGSVKEFLQTWKFFDGVDIAWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQ 325 Query: 165 EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAA 224 + +G+ L +A + V Y V+ +S+D + LM+YDFYG + G A Sbjct: 326 LSVETGRKYELTSAISAGKDMIDKVAYNVAQ--NSMDHIFLMSYDFYGAADLKNLGHQTA 383 Query: 225 LFDP---SNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNA--NSHSYYAPTTG 279 L P + + G + + G+ K V+G YG W N N+ + TG Sbjct: 384 LNAPAWKPDTAYTTVNGVNALLAQGVKPGKIVVGTAMYGRGWTGVNGYQNNIPFTGTATG 443 Query: 280 --AAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVR 335 +G + Y QI + Y++T Y + + + I +DD +S+ K + Sbjct: 444 PVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDARSVQAKGK 503 Query: 336 YAKQRGLLGYFSWHVGADDNSGLSRAAS 363 Y + L G FS + AD+ L+ + Sbjct: 504 YVLDKQLGGLFSAMIDADNGDILNSMNA 531 >3G6L-A nrPDB Length = 406 Score = 285 bits (728), Expect = 3e-77, Method: Composition-based stats. Identities = 102/362 (28%), Positives = 164/362 (45%), Gaps = 34/362 (9%) Query: 17 LTLQCSMAQTVVKASYW-FPASEFPVTDIDSSLFTHLFCAF---------------ADLN 60 L+ + + + V + W F D+ +S H+ +F ADL Sbjct: 14 LSTRATGSINAVYFTNWGIYGRNFQPADLQASKILHVLYSFMNLRVDGTVYSGDTYADLE 73 Query: 61 SQTNQVTVSSANQPKFSTFTQT--VQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKS 118 + + + + Q +++ N S+K +LSIGG + + AS +R + Sbjct: 74 KHYSDDSWNDIGTNAYGCVKQLYKLKKANRSLKIMLSIGGWTWSTN-FPAAASTEATRAT 132 Query: 119 FIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASS-SGKPRLLLA 177 F +++ + +GF G+D+DWEYP+S T+ N LL+ R + + +++ + L+ Sbjct: 133 FAKTAVEFMKDWGFDGIDVDWEYPASETDANNMVLLLQRVRQELDSYSATYANGYHFQLS 192 Query: 178 AAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALF----DPSNAGP 233 A ++Y+VL ++ + S LD +NLMAYD+ G W V+G L+ +PS+ Sbjct: 193 IAAPAGPSHYNVL-KLAQLGSVLDNINLMAYDYAG-SWDSVSGHQTNLYPSTSNPSSTPF 250 Query: 234 SGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQI 293 S A ++I AG+PA K +LG P YG A+ T+ Y T G G Y Sbjct: 251 STKAAVDAYIAAGVPASKIILGMPIYGRAFVGTDGPGKPY--STIGEGSWESGIWDY--- 305 Query: 294 RKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVG 351 K + GAT + +S Y Y + I YD + TKV YAK GL G W Sbjct: 306 -KVLPKAGATVITDSAAGATYSYDSSSRTMISYDTPDMVRTKVSYAKGLGLGGSMFWEAS 364 Query: 352 AD 353 AD Sbjct: 365 AD 366 >6EPB-A nrPDB Length = 423 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 109/356 (30%), Positives = 160/356 (44%), Gaps = 36/356 (10%) Query: 24 AQTVVKASYW-FPASEFPVTDIDSSLFTHLFCAF---------------ADLNSQTNQVT 67 V + W F D+ +S TH+ +F AD + Sbjct: 38 YANSVYFTNWGIYDRNFQPADLVASDVTHVIYSFMNLQADGTVISGDTYADYEKHYADDS 97 Query: 68 VSSANQPKFSTFTQT--VQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIR 125 + + Q V++ N +K LLSIGG + S AS +RK+F ++I Sbjct: 98 WNDVGTNAYGCVKQLFKVKKANRGLKVLLSIGGWTWSTN-FPSAASTDANRKNFAKTAIT 156 Query: 126 VARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASS--SGKPRLLLAAAVFYS 183 + +GF G+D+DWEYP+ AT+ +N LL+E RS + A A+ G LL AA Sbjct: 157 FMKDWGFDGIDIDWEYPADATQASNMILLLKEVRSQLDAYAAQYAPGYHFLLTIAAPAGK 216 Query: 184 NNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALF----DPSNAGPSGDAGT 239 +NY + ++ + LD++NLMAYD+ G +S +TG A LF +P+ + D+ Sbjct: 217 DNYSKLR--LADLGQVLDYINLMAYDYAG-SFSPLTGHDANLFNNPSNPNATPFNTDSAV 273 Query: 240 RSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVD 299 + +I G+PA K VLG P YG +++ T +Y G+ G Y K + Sbjct: 274 KDYINGGVPANKIVLGMPIYGRSFQNTAGIGQTYNG--VGSGSWEAGIWDY----KALPK 327 Query: 300 NGATTVYNSTVVGDYCYA--GTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 GAT Y+S G Y Y I +D I TKV Y K GL G W AD Sbjct: 328 AGATVQYDSVAKGYYSYNSATKELISFDTPDMINTKVAYLKSLGLGGSMFWEASAD 383 >1LL6-A nrPDB Length = 392 Score = 283 bits (725), Expect = 6e-77, Method: Composition-based stats. Identities = 99/357 (27%), Positives = 160/357 (44%), Gaps = 38/357 (10%) Query: 24 AQTVVKASYWF-PASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSS------------ 70 ++VV W D+ + FTH+ AFA++ + +V +S Sbjct: 3 FRSVVYFVNWAIYGRGHNPQDLKADQFTHILYAFANIRP-SGEVYLSDTWADTDKHYPGD 61 Query: 71 -ANQPKFSTFT-----QTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSI 124 ++P + + +++ N ++KTLLSIGG + + AS RK F D+S+ Sbjct: 62 KWDEPGNNVYGCIKQMYLLKKNNRNLKTLLSIGGWTYSPN-FKTPASTEEGRKKFADTSL 120 Query: 125 RVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASS--SGKPRLLLAAAVFY 182 ++ + GF G+D++WEYP + +F LL+ R A+ A ++ +GK LL A+ Sbjct: 121 KLMKDLGFDGIDINWEYPEDEKQANDFVLLLKACREALDAYSAKHPNGKKFLLTIASPAG 180 Query: 183 SNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALF----DPSNAGPSGDAG 238 NY + ++ + LD+ NLMAYDF G W +V+G + +F P + S D Sbjct: 181 PQNYNKL--KLAEMDKYLDFWNLMAYDFSG-SWDKVSGHMSNVFPSTTKPESTPFSSDKA 237 Query: 239 TRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIV 298 + +I+AG+PA K VLG P YG A+ T+ S+ G +G Y K + Sbjct: 238 VKDYIKAGVPANKIVLGMPLYGRAFASTDGIGTSFNG--VGGGSWENGVWDY----KDMP 291 Query: 299 DNGATTVYNSTVVGDYCYAGTN--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 GA + Y Y I YD + K Y + G+ G W +D Sbjct: 292 QQGAQVTELEDIAASYSYDKNKRYLISYDTVKIAGKKAEYITKNGMGGGMWWESSSD 348 >3WD0-A nrPDB Length = 503 Score = 276 bits (707), Expect = 8e-75, Method: Composition-based stats. Identities = 102/393 (25%), Positives = 163/393 (41%), Gaps = 67/393 (17%) Query: 39 FPVTDIDS---SLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQ---TVQRRNPSVKT 92 FPV++I TH+ +F D+NS + N K ++ NPS++ Sbjct: 35 FPVSNITPAKAKQLTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTALKAHNPSLRI 94 Query: 93 LLSIGGGIADK------TAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSAT 146 + SIGG Y + P +R F S +R+ + YGF G+D+DWEYP A Sbjct: 95 MFSIGGWYYSNDLGVSHANYVNAVKTPAARTKFAQSCVRIMKDYGFDGVDIDWEYP-QAA 153 Query: 147 EMTNFGTLLREWRSAVVAEASSSGKPRL--LLAAAVFYSNNYYSVLY-PVSAVASSLDWV 203 E+ F L+E R+ + + + G+ L L A + S Y ++ + + LD++ Sbjct: 154 EVDGFIAALQEIRTLLNQQTIADGRQALPYQLTIAGAGGAFFLSRYYSKLAQIVAPLDYI 213 Query: 204 NLMAYDFYGPGWSRVTGPPAALFD---------------------------PSNAGPSGD 236 NLM YD GP W ++T AALF PS + D Sbjct: 214 NLMTYDLAGP-WEKITNHQAALFGDAAGPTFYNALREANLGWSWEELTRAFPSPFSLTVD 272 Query: 237 AGT-RSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISP----------- 284 A + + G+P+ K V+G P+YG A++ + + Y+ + P Sbjct: 273 AAVQQHLMMEGVPSAKIVMGVPFYGRAFKGVSGGNGGQYSSHSTPGEDPYPNADYWLVGC 332 Query: 285 --------DGSIGYGQIRKFIVDN-GATTVYNSTVVGDYCYAGTN--WIGYDDNQSIVTK 333 Y Q+ + + N G ++N Y Y N ++ YDD +S K Sbjct: 333 DECVRDKDPRIASYRQLEQMLQGNYGYQRLWNDKTKTPYLYHAQNGLFVTYDDAESFKYK 392 Query: 334 VRYAKQRGLLGYFSWHVGADDNSGLSRAASQAW 366 +Y KQ+ L G WH+G D+ +G AA + Sbjct: 393 AKYIKQQQLGGVMFWHLGQDNRNGDLLAALDRY 425 >5DF0-A nrPDB Length = 545 Score = 267 bits (682), Expect = 7e-72, Method: Composition-based stats. Identities = 86/390 (22%), Positives = 145/390 (37%), Gaps = 67/390 (17%) Query: 36 ASEFPVTDIDSSLFTHLFCAFADLNS---------------------------------- 61 FPV + +HL F + Sbjct: 161 GRNFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTISGSFESLQRSCKGREDFKVAIHD 220 Query: 62 -----QTNQVTVSSANQPKFSTFTQTV--QRRNPSVKTLLSIGGGIADKTAYASMASNPT 114 Q Q +VS+ N+P F Q + + NP +K L SIGG Y + Sbjct: 221 PWAAVQKPQKSVSAWNEPYKGNFGQLMAAKLANPHLKILPSIGGWTLSDPFY--FMHDVE 278 Query: 115 SRKSFIDSSIRVARSYGF-HGLDLDWEYPSSAT----------EMTNFGTLLREWRSAVV 163 R F+DS + + F G+D+DWE+P + + LL E R+ + Sbjct: 279 KRNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAERDAKTYILLLEELRAMLD 338 Query: 164 AEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPA 223 + +G+ L +A + V Y + SL + LM+YDF G + G Sbjct: 339 DLEAQTGRVYELTSAISAGYDKIAVVNY--AEAQKSLGKIFLMSYDFKGAWSNTDLGYQT 396 Query: 224 ALFDPS---NAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTG- 279 ++ PS + + ++ G+ K ++G YG W ++ Y TG Sbjct: 397 TVYAPSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGN 456 Query: 280 ---AAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGT--NWIGYDDNQSIVTKV 334 + DG + Y QI+K + N ++S Y + + + I +D S++ KV Sbjct: 457 GPVSGTWEDGVVDYRQIQKDL--NNYVYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKV 514 Query: 335 RYAKQRGLLGYFSWHVGADDNSGLSRAASQ 364 +Y + L G F+W + AD+ L+ +Q Sbjct: 515 KYVDRNKLGGLFAWEIDADNGDLLNAINAQ 544 >6F8N-A nrPDB Length = 414 Score = 260 bits (665), Expect = 6e-70, Method: Composition-based stats. Identities = 89/385 (23%), Positives = 145/385 (37%), Gaps = 75/385 (19%) Query: 41 VTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFS-------------TFTQTVQRRN 87 + +D + THL +F + + Q T + P ++++N Sbjct: 31 INKLDVTQITHLNYSFGLIYNDEKQETNPALKDPSRLHQIYLSPKVMADLQLLPVLRKQN 90 Query: 88 PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP----- 142 P +K LLS+GG ++ A+ SR FI S +V + Y G+DLDW+YP Sbjct: 91 PELKVLLSVGGW--GARGFSGAAATAESRAVFIRSVQQVIKQYHLDGIDLDWQYPVNGAW 148 Query: 143 ----SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVAS 198 S + NF LL E A+ LL AV + V +A Sbjct: 149 GLVESQPADRANFTLLLAELHKALD--------KGKLLTIAVGANVKSPQEWVDVKGIAP 200 Query: 199 SLDWVNLMAYDF-YGPGWSRVTGPPAALFDPSN-------AGPSGDAGTRSWIQAGLPAK 250 LD++NLM YD YG + + L+D S + +++ AGL Sbjct: 201 YLDYINLMTYDMAYGTQYF-----NSNLYDSKQWPTVAAADRYSANFVVDNYLAAGLKPA 255 Query: 251 KAVLGFPYYGY----------AWRLTNANSHSYYAP-----------TTGAAISPDGSIG 289 + LG +YG W +A + P G ++ D Sbjct: 256 QLNLGIGFYGRVPKRATEPGIDWDKADAAKNPVTQPYFTARETAVFKAMGLDLTKDSYFK 315 Query: 290 YGQIRKFIVDN---GATTVYNSTVVGDYCYAGTNW------IGYDDNQSIVTKVRYAKQR 340 Y I ++++ T ++S Y + I Y++ +S+ K Y K + Sbjct: 316 YNDIVSKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKPLFAISYENPRSVALKADYIKSK 375 Query: 341 GLLGYFSWHVGADDNSGLSRAASQA 365 GL G W GADDN+ L+ +++ Sbjct: 376 GLGGAMFWEYGADDNNRLAHQLAES 400 >3ARQ-A nrPDB Length = 584 Score = 260 bits (664), Expect = 7e-70, Method: Composition-based stats. Identities = 90/421 (21%), Positives = 150/421 (35%), Gaps = 97/421 (23%) Query: 36 ASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQ---------------------- 73 ++ V ++ TH+ F + V N Sbjct: 151 GRDYTVDNMPVDNLTHILYGFIPICGPNESVKSVGGNSFNALQTACRGVNDYEVVIHDPW 210 Query: 74 ------------------PKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTS 115 +++RNP +K + SIGG Y + + + Sbjct: 211 AAYQKSFPQAGHEYSTPIKGNYAMLMALKQRNPDLKIIPSIGGWTLSDPFYDFV--DKKN 268 Query: 116 RKSFIDSSIRVARSYGF-HGLDLDWEYP----------SSATEMTNFGTLLREWRSAVVA 164 R +F+ S + +++ F G+D+DWE+P + + L+RE R + Sbjct: 269 RDTFVASVKKFLKTWKFYDGVDIDWEFPGGGGAAADKGDPVNDGPAYIALMRELRVMLDE 328 Query: 165 EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAA 224 + +G+ L +A + V + +D++ M YDFYG GW+ V G A Sbjct: 329 LEAETGRTYELTSAIGVGYDKIEDV--DYADAVQYMDYIFAMTYDFYG-GWNNVPGHQTA 385 Query: 225 LFDPS--------------------NAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAW- 263 L+ S + D G + + G+PA K VLG YG W Sbjct: 386 LYCGSFMRPGQCDGGGVDENGEPYKGPAYTADNGIQLLLAQGVPANKLVLGTAMYGRGWE 445 Query: 264 -----RLTNANS------HSYYAPTTGAAISPDGSIGYGQIRKFIVD------NGATTVY 306 LT+ N +T + DG I Y I+ F++ NG Y Sbjct: 446 GVTPDTLTDPNDPMTGTATGKLKGSTAQGVWEDGVIDYKGIKSFMLGANNTGINGFEYGY 505 Query: 307 NSTVVGDYCYA--GTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQ 364 ++ + + I +DD++S++ K YAK GL G FSW + AD+ L A + Sbjct: 506 DAQAEAPWVWNRSTGELITFDDHRSVLAKGNYAKSLGLAGLFSWEIDADNGDIL-NAMHE 564 Query: 365 A 365 Sbjct: 565 G 565 >1KFW-A nrPDB Length = 435 Score = 257 bits (657), Expect = 5e-69, Method: Composition-based stats. Identities = 92/430 (21%), Positives = 154/430 (35%), Gaps = 82/430 (19%) Query: 17 LTLQCSMAQTVVKASYWFPASE-FPVTDIDSS----LFTHLFCAFADLNSQTNQ------ 65 LT + + V + W F +D S TH+ +F ++N+QT Sbjct: 2 LTSTVNGYRNVGYFAQWGVYGRAFQAKQLDVSGTAKNLTHINYSFGNINNQTLTCFMANK 61 Query: 66 ------------------------------VTVSSANQPKFSTFTQT--VQRRNPSVKTL 93 + +QP +F Q ++ +NP +K + Sbjct: 62 AQGTGPNGSDGAGDAWADFGMGYAADKSVSGKADTWDQPLAGSFNQLKQLKAKNPKLKVM 121 Query: 94 LSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYG----------------FHGLDL 137 +S+GG K ++ A+ SR+ + S I + F G+D+ Sbjct: 122 ISLGGWTWSKN-FSKAAATEASRQKLVSSCIDLYIKGNLPNFEGRGGAGAAAGIFDGIDI 180 Query: 138 DWEYPSS-----------ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNY 186 DWE+P + + NF LL E+R + A S++ K +L A + Sbjct: 181 DWEWPGTNSGLAGNGVDTVNDRANFKALLAEFRKQLDAYGSTNNKKYVLSAFLPANPADI 240 Query: 187 YSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDP------SNAGPSGDAGTR 240 + + A SLD+ ++ YD +G +TG A L+D + S D + Sbjct: 241 DAGGWDDPANFKSLDFGSIQGYDLHGAWNPTLTGHQANLYDDPADPRAPSKKFSADKAVK 300 Query: 241 SWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDN 300 ++ AG+ K+ LG YG W S A + Y +++ D Sbjct: 301 KYLAAGIDPKQLGLGLAAYGRGWTGAKNVSPWGPATDGAPGTYETANEDYDKLKTLGTD- 359 Query: 301 GATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSR 360 Y++ + Y GT W YD+ + K Y +GL G W + D N L Sbjct: 360 ----HYDAATGSAWRYDGTQWWSYDNIATTKQKTDYIVSKGLGGGMWWELSGDRNGELVG 415 Query: 361 AASQAWDATT 370 A S + A Sbjct: 416 AMSDKFRAAA 425 >3QOK-A nrPDB Length = 420 Score = 251 bits (641), Expect = 4e-67, Method: Composition-based stats. Identities = 94/409 (22%), Positives = 159/409 (38%), Gaps = 81/409 (19%) Query: 23 MAQTVVKASYWFPASEFP------VTDIDSSLFTHLFCAFADLNSQTNQVTVSS------ 70 AQ ++ Y+ + + +D THL +F + + T ++ Sbjct: 22 SAQPLMSVGYFNGGGDVTAGPGGDIDKLDVRQITHLNYSFGLIYNDEKDETNAALKDPAH 81 Query: 71 ----ANQPKFSTFTQ---TVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSS 123 PK Q ++++NP +K LLS+GG ++ A+ SR FI S+ Sbjct: 82 LHEIWLSPKVQADLQKLPALRKQNPDLKVLLSVGGW--GARGFSGAAATAESRAVFIRSA 139 Query: 124 IRVARSYGFHGLDLDWEYP---------SSATEMTNFGTLLREWRSAVVAEASSSGKPRL 174 ++ + YG G+DLDWE+P S + NF LL+ R AV + Sbjct: 140 QKIIQQYGLDGIDLDWEFPVNGAWGLVASQPADRDNFTALLKSLREAV--------GEQK 191 Query: 175 LLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDF-YGPGWSRVTGPPAALFDPSN--- 230 L+ AV + V AVA L+++NLM YD YG + + L+D S+ Sbjct: 192 LVTIAVGANAESPKSWVDVKAVAPVLNYINLMTYDMAYGTQYF-----NSNLYDSSHWPT 246 Query: 231 ----AGPSGDAGTRSWIQAGLPAKKAVLGFPYYGY----------AWRLTNANSHSYYAP 276 S D +++ AGL + LG +YG W +A ++ P Sbjct: 247 VAAADKYSADFVVNNYLAAGLKPSQMNLGIGFYGRVPKRAVEPGIDWTKADAQNNPVTQP 306 Query: 277 -----------TTGAAISPDGSIGYGQIRKFI---VDNGATTVYNSTVVGDYCYAGTNW- 321 + G +S D + Y I + T ++ + + Sbjct: 307 YFGPQQIALFASLGYDLSKDTYVKYNDIVGKLLNDPQKRFTEHWDDEAKVPWLSVQSAEG 366 Query: 322 -----IGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 + Y++ +S+ K Y K +GL G W GADD + L+R +++ Sbjct: 367 KPLFALSYENPRSVAIKADYIKAKGLAGAMFWEYGADDQNQLARQLAES 415 >1JNE-A nrPDB Length = 420 Score = 233 bits (595), Expect = 8e-62, Method: Composition-based stats. Identities = 87/396 (21%), Positives = 146/396 (36%), Gaps = 64/396 (16%) Query: 40 PVTDIDSSLFTHLFCAFADLNSQTNQVTVSSAN-QPKFSTF--TQTVQRRNPSVKTLLSI 96 P +I +HL +A L + Q + N F +++R+ P +K LLS+ Sbjct: 24 PDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSV 83 Query: 97 GGGIA----DKTAYASMASNPTSRK-SFIDSSIRVARSYGFHGLDLDWEYPSSATEMTN- 150 GG Y + R+ FI S+ + ++YGF GLDL +++P + + Sbjct: 84 GGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYELVKTYGFDGLDLAYQFPKNKPRKVHG 143 Query: 151 ---------------------FGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSV 189 L +E +A+V + S + L + N + Sbjct: 144 DLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDVKDSLRADGFLLSLTVLPNVNSTW 203 Query: 190 LYPVSAVASSLDWVNLMAYDFYGPGWSRVTG-PPAALFDPSN-----AGPSGDAGTRSWI 243 + + A+ +D+VNL +DF P + A ++ P A + D W+ Sbjct: 204 YFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPIYHPDGSKDRLAHLNADFQVEYWL 263 Query: 244 QAGLPAKKAVLGFPYYGYAWRLTNAN---SHSYYAPTTGAAI-----SPDGSIGYGQIR- 294 G P+ K LG YG AW+LT + T+G A G + Y +I Sbjct: 264 SQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPETSGPAPEGFQSQKPGLLSYAEICG 323 Query: 295 -------KFIVDNGA--TTVYNSTVV-GDYCYAGTN-------WIGYDDNQSIVTKVRYA 337 +F+ N + V + T G Y + W+ YDD S K YA Sbjct: 324 KLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYA 383 Query: 338 KQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATT 373 + + L G + + DD G + + + A Sbjct: 384 RVKNLGGVALFDLSYDDFRG--QCSGDKYPILRAIK 417 >4W5U-B nrPDB Length = 408 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 85/373 (22%), Positives = 135/373 (36%), Gaps = 55/373 (14%) Query: 29 KASYW-FPASEFPVTDID----SSLFTHLFCAFADLN-------------------SQTN 64 + W F V ++D ++ TH+ AF ++ Q+ Sbjct: 46 YFTEWGTYDRNFNVKNLDTSGTAAKITHINYAFGNVTGGKCAIGDSYADYDKAFTADQSV 105 Query: 65 QVTVSSANQPKFSTFTQT--VQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDS 122 + +QP F Q ++ + P +K L S GG +A A +P + Sbjct: 106 SGQADTWDQPLRGNFNQLRQLKAKYPHIKVLWSFGGWTW-SGGFADAAKDPQGFAQSCYN 164 Query: 123 SIRVARSYG-FHGLDLDWEYPSSATEMTN------FGTLLREWRSAVVAEASSSGKPRLL 175 + R G F G+D+DWEYP++ + F L+ RS E L Sbjct: 165 LVHDPRWDGVFDGIDIDWEYPNACGLTCDSSGPDAFRNLMAALRSTFGDE---------L 215 Query: 176 LAAAVFYSNNY--YSVLYPVSAVASSLDWVNLMAYDFYGPGW-SRVTGPPAALFD---PS 229 + AAV + A +DW N+M YDF+G T P + L Sbjct: 216 VTAAVTADGTPGGKIEATDYAGAAQYVDWYNVMTYDFFGAWDAQGPTAPHSPLTSYDGIP 275 Query: 230 NAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIG 289 G + ++ G+PA K +LG +YG W ++ A A G Sbjct: 276 KQGFTSADAIAAFKAQGVPADKLLLGIGFYGRGWTGVTQDAPGGTATGPAAGTWEQGIED 335 Query: 290 YGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWH 349 Y ++ V + Y + G+N YD +I +K+ +A +GL G F+W Sbjct: 336 YKVLK------NTCPVTGTVAGTAYAHCGSNLWSYDTPDTIASKMAWANDQGLRGAFAWD 389 Query: 350 VGADDNSGLSRAA 362 D G AA Sbjct: 390 FSGDTADGELIAA 402 >4DWS-C nrPDB Length = 546 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 76/319 (23%), Positives = 132/319 (41%), Gaps = 32/319 (10%) Query: 75 KFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRV-ARSYGFH 133 + + SIGG ++++A NP R+ F+ S + R F Sbjct: 197 GLRELQKKAHAMGHKLDLAFSIGGWSLSS-YFSALAENPDERRVFVASVVDFFVRFPMFS 255 Query: 134 GLDLDWEYPS---------SATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSN 184 +D+DWEYP S + N+ L++E RSA+ + S + + +A + + Sbjct: 256 CVDIDWEYPGGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIACSGVKAK 315 Query: 185 NYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGP------SGDAG 238 S + + VA+ LD + LM+YDF+G W+ G L+ P + G S +A Sbjct: 316 LKKSNIDQL--VANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAA 373 Query: 239 TRSW-IQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFI 297 + G+P +K LG+ YG + + + Y +G+ + I K Sbjct: 374 IDYLHNELGIPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNY 433 Query: 298 VD---------NGATTVYNSTVVGDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYF 346 +D NG + ++ D+ + A ++I D +++ K YA + L G F Sbjct: 434 MDAEHSLSMGKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVF 493 Query: 347 SWHVGADDNSGLSRAASQA 365 SW G D L+ AA + Sbjct: 494 SWS-GDQDCGLLANAAREG 511 >6OGD-C nrPDB Length = 633 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 76/319 (23%), Positives = 132/319 (41%), Gaps = 32/319 (10%) Query: 75 KFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRV-ARSYGFH 133 + + SIGG ++++A NP R+ F+ S + R F Sbjct: 284 GLRELQKKAHAMGHKLDLAFSIGGWSLSS-YFSALAENPDERRVFVASVVDFFVRFPMFS 342 Query: 134 GLDLDWEYPS---------SATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSN 184 +D+DWEYP S + N+ L++E RSA+ + S + + +A + + Sbjct: 343 CVDIDWEYPGGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIACSGVKAK 402 Query: 185 NYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGP------SGDAG 238 S + + VA+ LD + LM+YDF+G W+ G L+ P + G S +A Sbjct: 403 LKKSNIDQL--VANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAA 460 Query: 239 TRSW-IQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFI 297 + G+P +K LG+ YG + + + Y +G+ + I K Sbjct: 461 IDYLHNELGIPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNY 520 Query: 298 VD---------NGATTVYNSTVVGDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYF 346 +D NG + ++ D+ + A ++I D +++ K YA + L G F Sbjct: 521 MDAEHSLSMGKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVF 580 Query: 347 SWHVGADDNSGLSRAASQA 365 SW G D L+ AA + Sbjct: 581 SWS-GDQDCGLLANAAREG 598 >5XWF-A nrPDB Length = 378 Score = 227 bits (579), Expect = 6e-60, Method: Composition-based stats. Identities = 92/368 (25%), Positives = 143/368 (38%), Gaps = 58/368 (15%) Query: 41 VTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGI 100 I H+ AFA T +S + + Q R S LS+GG Sbjct: 14 PKSIAWDKLDHIVYAFA---EPTKDGELSGFTDSQLKSVVQEAHSRGKS--ISLSVGGWT 68 Query: 101 ADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSA----------TEMTN 150 ++ + + +S +F+ + + V + Y GL+LDWEYP+S + N Sbjct: 69 -GSLYFSDLLKSSSSFDNFVSNLVDVVKEYDLDGLNLDWEYPNSPNGVACNSKDENDTAN 127 Query: 151 FGTLLREWRSAVVAEASSSGKPRLLLAA---AVFYSNNYYSVLYPVSAVASSLDWVNLMA 207 + L + R + G +L A A F N AS++D +MA Sbjct: 128 YLKLFKALREKL-------GSKTILTTAVPTAPFNDENQQPSTKLDDNWASTVDAFYIMA 180 Query: 208 YDFYGPGWSRVTGPPAAL-FDPSNAG---PSGDAGTRSWIQAGLPAKKAVLGFPYYGYAW 263 YD G + G A L + P G SG+ ++WI AG+PA++ VLG P+YG Sbjct: 181 YDVNGIR-DKNAGANAPLYYSPKVTGVEPTSGNDAVKAWIAAGIPAEQLVLGVPFYGRVS 239 Query: 264 RLTNA--NSHSYYAPTT-------------GAAISPDGSIGYGQ--IRKFIVD------- 299 + S Y P + A P+ Y I + I Sbjct: 240 KTLEPITASTGLYVPISQSSQIKGDSTDEKAADPCPNAVATYSGQYIWRTIAQEGIARNS 299 Query: 300 NGATTVYNSTVVGDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDN-S 356 +G T ++ Y Y +G+ + +DD S+ KV YAK++GL G W + DD+ + Sbjct: 300 SGWVTYWDDISKTPYAYSFSGSKVLSFDDAASLQDKVDYAKKQGLGGVMLWSLEMDDDEN 359 Query: 357 GLSRAASQ 364 L A Sbjct: 360 TLLNALQD 367 >4A5Q-A nrPDB Length = 546 Score = 221 bits (562), Expect = 5e-58, Method: Composition-based stats. Identities = 80/360 (22%), Positives = 132/360 (36%), Gaps = 49/360 (13%) Query: 41 VTDIDSSLFTHLFCAF-----ADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLS 95 D D ++ + C F D N + NQ F + + + ++ LS Sbjct: 161 PVDPDGAVLASINCGFTKWEAGDANERYNQEKAKGL----LGGF-RLLHEADKELEFSLS 215 Query: 96 IGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYG-FHGLDLDWEYPSS--------AT 146 IGG + ++ +A + R +F++ + + F LD+DWEYP S Sbjct: 216 IGGW-SMSGLFSEIAKDEILRTNFVEGIKDFFQRFPMFSHLDIDWEYPGSIGAGNPNSPD 274 Query: 147 EMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLM 206 + NF L+++ A ++ ++ A + + + + +NLM Sbjct: 275 DGANFAILIQQITDAKISNLKG-------ISIASSADPAKIDAANIPALMDAGVTGINLM 327 Query: 207 AYDFYGPGWSRVTGPPAALFDPSNAGPSG---DAGTRSWIQAGLPAKKAVLGFPYYGYAW 263 YDF+ G +++ DPS+ DA T + + K +G+ Y Sbjct: 328 TYDFFTLGDGKLSHHTNIYRDPSDVYSKYSIDDAVTHLIDEKKVDPKAIFIGYAGYTRNA 387 Query: 264 RL----TNANSHSYYAPTTGAAISPDGSIGYG------------QIRKFIVDNGATTVYN 307 + T+ S T A GS Y K NG V++ Sbjct: 388 KNATITTSIPSEEALKGTYTDANQTLGSFEYSVLEWTDIICHYMDFEKGEGRNGYKLVHD 447 Query: 308 STVVGDYCY--AGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 DY Y A +I D +S+ K RY K +GL G F W G DN L+ AA + Sbjct: 448 KVAKADYLYSEATKVFISLDTPRSVRDKGRYVKDKGLGGLFIWS-GDQDNGILTNAAHEG 506 >4TXG-A nrPDB Length = 793 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 96/472 (20%), Positives = 154/472 (32%), Gaps = 131/472 (27%) Query: 22 SMAQTVVKASYWFPASE----FPVTDIDSSLFTHLFCAFADLNSQT----------NQVT 67 S + + + W + + +DI S TH+ AFA ++ N T Sbjct: 152 SRRRIIGYFTSWRTGKDGSPAYLASDIPWSKLTHINYAFAHVDGSNKLSVNETAPGNPAT 211 Query: 68 VSSA----------NQPKFSTFT--QTVQRRNPSVKTLLSIGGGIADKTAY--------- 106 S + P F +R+ P VKTL+S+GG + Sbjct: 212 DMSWPGVAGAEMDASLPYKGHFNLLTQYKRKYPGVKTLISVGGWAETGGYFDANGKRVAS 271 Query: 107 ---------ASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTN------- 150 A N +F DS++ R YGF G+D+D+EYP+S N Sbjct: 272 GGFYSMTVNADGTVNQAGINAFSDSAVAFLRKYGFDGVDIDFEYPTSMNNAGNPLDWTFS 331 Query: 151 ----------FGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 + LL+ R + A+ G+ + AA Y L Sbjct: 332 NARLGSLNKGYVALLQTLRDRLDRAAAQDGRYYQITAAVPASG--YLLRGMETFQGLKYL 389 Query: 201 DWVNLMAYDFYGPGWSRVTGPPAALFDP-----------------SNAGPSGDAGTRSWI 243 D+VN+M+YD +G W+R GP AAL+D N G + Sbjct: 390 DFVNVMSYDLHG-AWNRFVGPNAALYDDGKDAELAFWNVYSTPQYGNIGYLNTDWAYHYY 448 Query: 244 QAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISP------DGSIGYGQIRKFI 297 + GLPA + +G PYY W+ + S+ + + G+ DG++G I + Sbjct: 449 RGGLPASRVNMGVPYYTRGWKNVSGGSNGLWGSSVGSNCPAGLTECGDGAVGIDNIWHDL 508 Query: 298 VDNG------------------------------------------ATTVYNSTVVGDYC 315 D+G YN + + Sbjct: 509 DDSGKEIPGGSNPMWHAKNLEKGLAGSYLAAYGIDPTLPINQLTGSYQRNYNGALAAPWL 568 Query: 316 YAGTN--WIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQA 365 + ++ +D QSI K + + G W + D + R Q Sbjct: 569 WNAGKKVFLSTEDEQSIAQKAAWIDANNVGGVMFWELAGDYDWKAQRNNGQG 620 >3CO4-A nrPDB Length = 312 Score = 186 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 69/325 (21%), Positives = 120/325 (36%), Gaps = 59/325 (18%) Query: 33 WFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKT 92 W S FP I+ TH+ +FA + + + ++ + + + +T + N VK Sbjct: 15 WEFESLFPT--IEWKYLTHINASFARVKAD-GTLNINPV-RKRIESVRETAHKHN--VKI 68 Query: 93 LLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFG 152 L+S+ + + ++P +RK I I + Y G D+D+E + + NF Sbjct: 69 LISLAKN--SPGEFTTAINDPKARKELIQQIIAFTKEYKLDGFDIDYEEYDNWDK--NFP 124 Query: 153 TLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYG 212 +LL R +A+ + +L+ AV L + D++NLM+YD Sbjct: 125 SLLVFARGLYLAKEKN-----MLMTCAV-----NSRWLNYGTEWEQYFDYINLMSYD--- 171 Query: 213 PGWSRVTGPPAALFDPSNAGPSGDAGT---RSWIQAGLPA-KKAVLGFPYYGYAWRLTNA 268 A D S D + W + + K V G P+YGY+W Sbjct: 172 ---------RGAFTDKPVQHASYDDFVKDLKYWNEQCRASKSKIVGGLPFYGYSWE---- 218 Query: 269 NSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQ 328 + A+ I Y I K + + A + +G Y G Sbjct: 219 -------ESLQGAVDDVRGIRYSGILKHLGNEAA----DKDNIGKTYYNGR--------P 259 Query: 329 SIVTKVRYAKQRGLLGYFSWHVGAD 353 +I K ++ K+ G W + D Sbjct: 260 TIANKCKFIKENDYAGVMIWQLFQD 284 >3CZ8-A nrPDB Length = 319 Score = 167 bits (424), Expect = 6e-42, Method: Composition-based stats. Identities = 64/318 (20%), Positives = 130/318 (40%), Gaps = 44/318 (13%) Query: 39 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGG 98 + S+F + D+ +Q N + T QRR + T+ ++ Sbjct: 29 YAPYSSSISIFEYHIAPNGDIANQLNDA----------AAIETTWQRRVTPLATITNLTS 78 Query: 99 GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREW 158 G + +NPT+R + +++ + + G+ G+ +D+E SA + F LR+ Sbjct: 79 GGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGYGGVTIDFE-QVSAADRDLFTGFLRQL 137 Query: 159 RSAVVAEASSSGKPRLLLAAAVFYSNNY-YSVLYPVSAVASSLDWVNLMAYDFYGPGWSR 217 R + A G L +A S+N + Y + + ++++ +MAYD++ G Sbjct: 138 RDRLQA-----GGYVLTIAVPAKTSDNIPWLRGYDYGGIGAVVNYMFIMAYDWHHAGSEP 192 Query: 218 VTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPT 277 GP A + + T + A +P++K ++G P YGY W + Y T Sbjct: 193 --GPVAPITEIRR--------TIEFTIAQVPSRKIIIGVPLYGYDWII------PYQPGT 236 Query: 278 TGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGD-YCYAG----TNWIGYDDNQSIVT 332 +AIS +I + A Y++ + Y+ T+ + ++ +S+ Sbjct: 237 VASAISNQNAIE------RAMRYQAPIQYSAEYQSPFFRYSDQQGRTHEVWFEGVRSMSR 290 Query: 333 KVRYAKQRGLLGYFSWHV 350 K++ ++ L +W + Sbjct: 291 KMQIVREYRLQAIGAWQL 308 >4WIW-A nrPDB Length = 349 Score = 160 bits (405), Expect = 8e-40, Method: Composition-based stats. Identities = 63/317 (19%), Positives = 120/317 (37%), Gaps = 40/317 (12%) Query: 57 ADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSR 116 + + + V + T +K L I G A ++ +P +R Sbjct: 43 GSIGTDGSLKLVWDEGSSNYKQLTNMAHGL--GMKVLPLINGSGATLN---TLLKSPAAR 97 Query: 117 KSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTN----FGTLLREWRSAVVAEASSSGKP 172 + I + + ++ G+ +D+E P ++ + L + ++ +E S K Sbjct: 98 EKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKL 157 Query: 173 RLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAG 232 ++ S+ Y+ Y A++ ++D++++M YD + + GP A Sbjct: 158 VVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHH--YRTSAPGPIAP-------Y 208 Query: 233 PSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRL--TNANSHSYYAPTTGAAISPDGSIGY 290 P G+ K ++G PYYG W + +AN + Y T + GY Sbjct: 209 PWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNST---------AFGY 259 Query: 291 GQIRKFIVDNGATTVY----NSTVVGDYCYAGTNWIG------YDDNQSIVTKVRYAKQR 340 + + GAT Y ++ VG + T+ G +DD S K+ + Sbjct: 260 SKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEF 319 Query: 341 GLLGYFSWHVG-ADDNS 356 GL G W +G D+N+ Sbjct: 320 GLAGVGPWAMGWVDENT 336 >4S3K-A nrPDB Length = 436 Score = 159 bits (402), Expect = 2e-39, Method: Composition-based stats. Identities = 54/274 (19%), Positives = 106/274 (38%), Gaps = 39/274 (14%) Query: 90 VKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMT 149 + L +I G ++ +N + + +++ ++ A+ F + D+E+ + Sbjct: 171 LMVLANIENGAFSDEVGRAILNNKDVQDTLLNNIVKTAKEQNFRDIHFDFEF-LRPADKE 229 Query: 150 NFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNY-----YSVLYPVSAVASSLDWVN 204 + L++ + + E +LL++ A+ + + + A+ ++V Sbjct: 230 AYIAFLQKAKKRLQDE-------QLLMSVALAPKTSRDQKGKWYEAHDYKAIGEIANFVV 282 Query: 205 LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWR 264 M Y+ W GPP A+ S GP D + + +P+ K ++G YGY W Sbjct: 283 PMTYE-----WGYSGGPPMAV---SPIGPVRD--VLEYAVSEIPSSKIIMGQNLYGYDWT 332 Query: 265 LTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDY-CYAG----T 319 L Y AISP +I K + Y++ + Y T Sbjct: 333 LPYKPGGEY-----AKAISPQRAIELAARYKVAIQ------YDNKAQAPFFRYKDEQQRT 381 Query: 320 NWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 + + ++D +SI K K+ L G W +G D Sbjct: 382 HEVWFEDARSIQAKFDLIKELKLRGMAYWKLGLD 415 >4Q6T-A nrPDB Length = 351 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 57/266 (21%), Positives = 99/266 (37%), Gaps = 24/266 (9%) Query: 99 GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREW 158 G D S+ ++ + +++A+ GF G++LD+E E N Sbjct: 81 GAFDPAISHSILNDRALSAGTVKQLVKLAKEGGFAGINLDFE----KVEPRNRAAFCAFV 136 Query: 159 RSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRV 218 ++ A +S+ K + + + + Y Y A+ +++D+ +M YD GPGWS Sbjct: 137 KTLGNALHASNKKLIISIPPKLSDTEPEYLQGYDYKALGAAVDYFQVMTYDQVGPGWSSG 196 Query: 219 TGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTT 278 A + +G S+ + +PA K + G P YG + + N S Y Sbjct: 197 GFHNEA-WPGPESGFDWQQALLSYAVSRVPASKVLAGLPTYGQDYSIGNRVHWSAYQEII 255 Query: 279 GA--------AISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSI 330 A S +G ++ F+ T + YDD SI Sbjct: 256 AEHRAAIHRDAASATPYATWGPVKSFVDGVEWTPE-----------RAQPVLWYDDAASI 304 Query: 331 VTKVRYAKQRGLLGYFSWHVGADDNS 356 TK + GL G W +G ++ Sbjct: 305 KTKTALVTRLGLGGTSVWAMGYENAG 330 >4S3J-A nrPDB Length = 433 Score = 149 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 59/315 (18%), Positives = 119/315 (37%), Gaps = 37/315 (11%) Query: 44 IDSSLFTHLFC-AFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIAD 102 I+ L T+L +F T + +A +T QT+ P + + +I G Sbjct: 129 INPFL-TYLAYFSFEAKRDGTLKEPTETAKIANIATQGQTI----PML-VITNIENGNFS 182 Query: 103 KTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAV 162 + + + T + FI + ++ A YG + D+E + + + LR + + Sbjct: 183 ADLTSVILRDATIQNKFITNILQTAEKYGMRDIHFDFE-SVAPEDREAYNRFLRNVKIRL 241 Query: 163 VAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPP 222 + + S L+ + + A +D+V +M YD W GPP Sbjct: 242 PSGYTLSTT---LVPKTSSNQKGKFFEAHDYKAQGQIVDFVVIMTYD-----WGWQGGPP 293 Query: 223 AALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAI 282 A+ S GP + + ++ +P +K ++G YG+ W+L + A+ Sbjct: 294 MAI---SPIGPVKE--VLQYAKSQMPPQKIMMGQNLYGFDWKLPFKQGNP-----PAKAV 343 Query: 283 SPDGSIGYGQIRKFIVDNGATTVYNSTVVGDY--CYAGT---NWIGYDDNQSIVTKVRYA 337 S ++ Y+ T + + + + ++D +SI +K Sbjct: 344 SSVAAVALA------RKYNVPIRYDFTAQAPHFNYFDENGVQHEVWFEDARSIQSKFNLM 397 Query: 338 KQRGLLGYFSWHVGA 352 K++G+ G W +G Sbjct: 398 KEQGIGGISYWKIGL 412 >5JH8-A nrPDB Length = 317 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 47/267 (17%), Positives = 101/267 (37%), Gaps = 42/267 (15%) Query: 97 GGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLR 156 G G +++++ S+ + + ++ A+ F G+++D+E + + NF ++ Sbjct: 72 GNGNWSADIAHAVSTSAQSQA--VANLVKFAQDKRFSGINVDFE-AVAQGDRNNFSHFIQ 128 Query: 157 EWRSAVVAEASSSGKPRLLLAAAVFYSNNYY---SVLYPVSAVASSLDWVNLMAYDFYGP 213 A+ A+ +L+++ F + + + Y + A+ ++ D++ +M+YD P Sbjct: 129 VLGRALHAKG-----LKLIVSVPAFSAKDENHPANYGYDLRALGAAADYLQIMSYDEAIP 183 Query: 214 GWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSY 273 W AG + +PA K + G P YGY W+ Y Sbjct: 184 AWDP----------GPVAGSDWMEDDLDYAVERVPAAKILNGIPAYGYDWKRPGDGGMLY 233 Query: 274 YAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVG-DYCYAG----TNWIGYDDNQ 328 + T I GA Y++ + Y + + ++ + Sbjct: 234 WKDTQA----------------LIARYGAQPRYDAGTHSLTFNYGAADGSRHTVWTENAR 277 Query: 329 SIVTKVRYAKQRGLLGYFSWHVGADDN 355 S+ K GL G + +G +D+ Sbjct: 278 SVALKASLVNAYGLGGTSLYALGMEDD 304 >3BXW-B nrPDB Length = 393 Score = 75.9 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 55/343 (16%), Positives = 117/343 (34%), Gaps = 61/343 (17%) Query: 29 KASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQV-TVSSANQPKFSTFTQTVQRRN 87 + W + VT + S FT + + L + ++ V+ + + + V++ Sbjct: 84 YVTPWNSHG-YDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQG-WMRAVRKHA 141 Query: 88 PSVKTLLSI--GGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLD-WEYPSS 144 + + + D + ++ + + + ++VA++ F G ++ W + Sbjct: 142 KGLHIVPRLLFEDWTYDD--FRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVW----N 195 Query: 145 ATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYS--VLYPVSAVASSLDW 202 L+ A + L++ A+ + +A LD Sbjct: 196 QLLSQKRVGLIHMLTHLAEALHQARLLALLVIPPAITPGTDQLGMFTHKEFEQLAPVLDG 255 Query: 203 VNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLP--------AKKAVL 254 +LM YD+ GP A L SW++A + K +L Sbjct: 256 FSLMTYDYSTA---HQPGPNAPL---------------SWVRACVQVLDPKSKWRSKILL 297 Query: 255 GFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTV-VGD 313 G +YG + A S P GA + + + D+ V++S Sbjct: 298 GLNFYGMDY----ATSKDAREPVVGA-----------RYIQTLKDHRPRMVWDSQASEHF 342 Query: 314 YCYA----GTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGA 352 + Y G + + Y +S+ ++ A++ G+ G W +G Sbjct: 343 FEYKKSRSGRHVVFYPTLKSLQVRLELARELGV-GVSIWELGQ 384 >3EBV-A nrPDB Length = 302 Score = 58.5 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 54/304 (17%), Positives = 99/304 (32%), Gaps = 47/304 (15%) Query: 31 SYWF-PASEFPVTDID--SSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFT------Q 81 YW + V I S + + AFAD + VT + + +T Sbjct: 9 GYWQNFNNGATVQKISDVPSAYDIIAVAFADATTTPGAVTFN-LDSAGLGGYTVDQFKAD 67 Query: 82 TVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEY 141 ++ K ++S+GG + +S ++ +F +S V R YGF G+D+D E Sbjct: 68 VRAKQAAGKKVIISVGGEKGTVSVNSSASAT-----NFANSVYSVMREYGFDGVDIDLEN 122 Query: 142 PSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVA--SS 199 + T A+ A ++ +G +L A Y +A+ Sbjct: 123 GLNPT----------YMTQALRALSAKAGPDMILTMAPQTIDMQSTQGGYFQTALNVKDI 172 Query: 200 LDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYY 259 L VN+ Y + G ++ ++ GL + LG P Sbjct: 173 LTVVNMQYY-----NSGTMLGCDGKVYAQGTVDFLTALACIQ-LEGGLAPSQVGLGLP-- 224 Query: 260 GYAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNG---ATTVYNSTVV 311 T A Y +P+ A + + + G +T +++T Sbjct: 225 ----ASTRAAGGGYVSPSVVNAALDCLTKATNCGSFKPSKTYPDLRGAMTWSTNWDATAG 280 Query: 312 GDYC 315 + Sbjct: 281 NAWS 284 >4TX8-A nrPDB Length = 439 Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 20/145 (13%) Query: 30 ASYWF-----PASEFPVTDI--DSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQT 82 YW S FP++ + D + + AFAD N + F Q Sbjct: 110 VGYWHNFANPSGSAFPLSQVSADWDV---IVVAFADDAGNGNVSFTLDPAAGSAAQFIQD 166 Query: 83 VQRRN-PSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEY 141 ++ + K +LS+GG T +N T ++F++S + YGF G+DLD E Sbjct: 167 IRAQQAKGKKVVLSLGGQNGSVT-----LNNATQVQNFVNSLYGILTQYGFDGIDLDLES 221 Query: 142 PS----SATEMTNFGTLLREWRSAV 162 S A ++N + +++ ++ + Sbjct: 222 GSGIVVGAPVVSNLVSAVKQLKAKI 246 >4RL3-A nrPDB Length = 272 Score = 53.5 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 69/188 (36%), Gaps = 13/188 (6%) Query: 29 KASYWFPASEFPVTDIDSSLFTHLFCAFA-----DLNSQTNQVTVSSANQPKFSTFTQTV 83 + +F I+S + H AFA + + N Q + Sbjct: 7 YIGALYNGVQFTDVPINSGVTFHFILAFAIDYTSAAAATNGVFNIYWQNSVLTPAAVQAI 66 Query: 84 QRRNPSVKTLLSIGGGIADKTAYASMASNPTS-RKSFIDSSIRVARSYGFHGLDLDWEYP 142 + ++ +VK ++S+GG + A++ +S + + S + Y G+D+D+E+ Sbjct: 67 KAQHSNVKVMVSLGGDTISGSPVQFTATSVSSWVANAVSSLTSLINQYHLDGIDIDYEHF 126 Query: 143 SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDW 202 + + F + + + + + A + +A+ + +S +D Sbjct: 127 DQVS-TSTFVSCIGQLITQLKANNV------ISVASIAPFDGVESQYTALFGQYSSVIDL 179 Query: 203 VNLMAYDF 210 VN Y + Sbjct: 180 VNFQFYSY 187 >3IAN-A nrPDB Length = 321 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 39/219 (17%), Positives = 73/219 (33%), Gaps = 27/219 (12%) Query: 52 LFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMAS 111 + +F T N+ + + L+++GG A + Sbjct: 42 INVSFMKTPEGQTLPTFKPYNKTDTEFRAEISKLNAEGKSVLIALGGADAH----IELKK 97 Query: 112 NPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGK 171 + S F++ IR+ +YGF GLD+D E ++ N + + Sbjct: 98 SQES--DFVNEIIRLVDTYGFDGLDIDLE-QAAIEAADNQTVIPSALKKVKDHYRKD--G 152 Query: 172 PRLLLAAAVFYSNNYYSVLY--PVSAVASSLDWVNLMAYDFYGPG-WSRVTG---PPAA- 224 ++ A + S Y ++ + S D++N Y+ G G W + Sbjct: 153 KNFMITMAPEFPYLTSSGKYAPYINNLDSYYDFINPQYYNQGGDGFWDSDLNMWISQSND 212 Query: 225 ------LFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFP 257 L+ + +G G +PA K V+G P Sbjct: 213 EKKEDFLYGLTQRLVTGTDGFIK-----IPASKFVIGLP 246 >1NAR-A nrPDB Length = 290 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 75/188 (39%), Gaps = 32/188 (17%) Query: 39 FPVTDIDSSLFT-HLFCAFA-DLNSQTNQVTVS---SANQPKFS-TFTQTVQRRNPSVKT 92 FP I++ H FA + ++ + T + S + F + ++RR+P VK Sbjct: 21 FPTEIINTETLEFHYILGFAIESYYESGKGTGTFEESWDVELFGPEKVKNLKRRHPEVKV 80 Query: 93 LLSIGGGIADKTAYASMASNPTSRKSFIDSSIR----VARSYG------FHGLDLDWEYP 142 ++SIGG + +P ++ ++ + + Y G+D+ +E+ Sbjct: 81 VISIGGRGVNTPF------DPAEENVWVSNAKESLKLIIQKYSDDSGNLIDGIDIHYEHI 134 Query: 143 SSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDW 202 S F TL+ + + + + ++ A ++++Y LY D+ Sbjct: 135 RSD---EPFATLMGQLITELKKD--DDLNINVVSIAPSENNSSHYQKLYNAKK-----DY 184 Query: 203 VNLMAYDF 210 +N + Y F Sbjct: 185 INWVDYQF 192 >3N18-A nrPDB Length = 333 Score = 51.2 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 52 LFCAFADLNSQTNQVTVSSA--NQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASM 109 + +F + + V S F + ++ + K +LSIGG + Sbjct: 35 INVSFGETGGDRSTVEFSPVYGTDADFKSDISYLKSKGK--KVVLSIGGQNG-----VVL 87 Query: 110 ASNPTSRKSFIDSSIRVARSYGFHGLDLD 138 + ++ FI+S + YGF G+D+D Sbjct: 88 LPDNAAKDRFINSIQSLIDKYGFDGIDID 116 >4AXN-A nrPDB Length = 328 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 37/182 (20%), Positives = 60/182 (32%), Gaps = 33/182 (18%) Query: 92 TLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNF 151 L+S+GG A + D IR+ YGF GLD+D E ++ N Sbjct: 99 VLISLGGADAH------IELKTGDEDKLKDEIIRLVEVYGFDGLDIDLE-QAAIGAANNK 151 Query: 152 GTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMA--YD 209 L + A+ +++ A + + Y LD++N + YD Sbjct: 152 TVLPAALKKVKDHYAAQ--GKNFIISMAPEFPYLRTNGTY--------LDYINALEGYYD 201 Query: 210 FYGPGWSRVTG-----PPAALFDPSNAGPSGDAGTRSWIQ---------AGLPAKKAVLG 255 F P + G + N + + A +PA K V+G Sbjct: 202 FIAPQYYNQGGDGIWVDELNAWITQNNDAMKEDFLYYLTESLVTGTRGYAKIPAAKFVIG 261 Query: 256 FP 257 P Sbjct: 262 LP 263 >3SIM-A nrPDB Length = 275 Score = 48.1 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 51/130 (39%), Gaps = 11/130 (8%) Query: 82 TVQRRNPSVKTLLSIGGGIADKTAYASMASNPTS-RKSFIDSSIRVARSYGFHGLDLDWE 140 ++ +P+V+ +S+GG A++ S + + S R+ + Y G+D+D+E Sbjct: 68 AIKSSHPNVRVAVSLGGASVGSNTVQFQAASVDSWVSNAVTSLTRIIQRYNLDGIDIDYE 127 Query: 141 YPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 +F + + + ++ K +++ A Y ++ Sbjct: 128 ---------HFQNTDKNTFAECIGRLITTLKKNGVISFASISPFPSVDEYY-LALFNEYK 177 Query: 201 DWVNLMAYDF 210 + +N + Y F Sbjct: 178 NAINHINYQF 187 >1EDT-A nrPDB Length = 271 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 33/172 (19%), Positives = 57/172 (33%), Gaps = 28/172 (16%) Query: 57 ADLNSQTNQVTV-----SSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMAS 111 A++N T T + + + TQ + +K LLS+ G +A+ S Sbjct: 46 ANINYDTGTKTAYLHFNENVQRVLDNAVTQIRPLQQQGIKVLLSVLGNHQGA-GFANFPS 104 Query: 112 NPTSRKSFIDSSIRVARSYGFHGLDLD---WEYPSSATEMTNFGTLLREWRSAVVAEASS 168 + +F YG G+D D EY ++ T N + + Sbjct: 105 QQAA-SAFAKQLSDAVAKYGLDGVDFDDEYAEYGNNGTAQPNDSSFVH------------ 151 Query: 169 SGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTG 220 L+ A + LY + AS L + + D + W+ G Sbjct: 152 ------LVTALRANMPDKIISLYNIGPAASRLSYGGVDVSDKFDYAWNPYYG 197 >2Y8V-A nrPDB Length = 290 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 35/95 (36%), Gaps = 7/95 (7%) Query: 50 THLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQR----RNPSVKTLLSIGGGIADKTA 105 TH+ A LN +T++ + P + + VK + +GG Sbjct: 43 THIIIAAFHLNEDPGHITLND-DPPDHEMYNPLWAEVPVLKRSGVKVMGMLGGAAQGS-- 99 Query: 106 YASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWE 140 Y + + + + + + R + GLDLD E Sbjct: 100 YRCLDGDQEKFERYYQPLLAMVRRHQLDGLDLDVE 134 >4W5Z-A nrPDB Length = 345 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 55/172 (31%), Gaps = 14/172 (8%) Query: 92 TLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNF 151 L+++GG A + + IR+ YGF GLD+D E + + F Sbjct: 111 VLIALGGADAH------IELTRGDEDALAAEIIRLTDLYGFDGLDIDLEQAAITAKDNQF 164 Query: 152 GTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV-SAVASSLDWVNLMAYDF 210 + V +G ++ A F P + + D++N Y+ Sbjct: 165 V--IPAALKMVKEHYRKTGDNFMITMAPEFPYLTANGAYTPYLTELDGYYDFINPQFYNQ 222 Query: 211 YGPG-WSRVTGPPAALFD---PSNAGPSGDAGTRSWIQ-AGLPAKKAVLGFP 257 G G W G A D D+ +P K V G P Sbjct: 223 GGDGLWIEGVGWIAQNNDALKEEFIYYIADSLINGTRNYHKIPHDKLVFGLP 274 >4MB4-A nrPDB Length = 528 Score = 41.2 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 55/172 (31%), Gaps = 14/172 (8%) Query: 92 TLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNF 151 L+++GG A + + IR+ YGF GLD+D + + + F Sbjct: 89 VLIALGGADAH------IELTRGDEDALAAEIIRLTDLYGFDGLDIDLQQAAITAKDNQF 142 Query: 152 GTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV-SAVASSLDWVNLMAYDF 210 + V +G ++ A F P + + D++N Y+ Sbjct: 143 V--IPAALKMVKEHYRKTGDNFMITMAPEFPYLTANGAYTPYLTELDGYYDFINPQFYNQ 200 Query: 211 YGPG-WSRVTGPPAALFD---PSNAGPSGDAGTRSWIQ-AGLPAKKAVLGFP 257 G G W G A D D+ +P K V G P Sbjct: 201 GGDGLWIEGVGWIAQNNDALKEEFIYYIADSLINGTRNYHKIPHDKLVFGLP 252 >6MDV-A nrPDB Length = 802 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 32/242 (13%), Positives = 71/242 (29%), Gaps = 39/242 (16%) Query: 64 NQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSS 123 + + S ++ + ++ ++ + + P K+ + Sbjct: 67 HTASDSPFWSELKDSYVHKLHQQGTALVQTIGVNELNGRTGLSKDYPDTPEGNKALAAAI 126 Query: 124 IR-VARSYGFHGLDLDWEY----PSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAA 178 ++ G GLD+D E+ + E + +E + S K ++ Sbjct: 127 VKAFVTDRGVDGLDIDIEHEFTNKRTPEEDARALNVFKEIAQLIGKNGSDKSKLLIMDTT 186 Query: 179 AVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAG 238 +N + +A LD++ L Y + D Sbjct: 187 LSVENNPIF------KGIAEDLDYL-LRQY-----------------YGSQGGEAEVDTI 222 Query: 239 TRSWIQAG--LPAKKAVLGFPYY------GYAWRLTNANSHSYYAPTTGAAISPDGSIGY 290 W Q + A + ++GF ++ G W + N + P G I + Y Sbjct: 223 NSDWNQYQNYIDASQFMIGFSFFEESASKGNLW--FDVNEYDPNNPEKGKDIEGTRAKKY 280 Query: 291 GQ 292 + Sbjct: 281 AE 282 >2EBN-A nrPDB Length = 289 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 59/169 (34%), Gaps = 11/169 (6%) Query: 37 SEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQ-RRNPSVKTLLS 95 S P+ D+ ++ D + V+ + Q + + ++ ++ +K +LS Sbjct: 34 SGKPLVDMVVLFSANINY---DAANDKVFVSNNPNVQHLLTNRAKYLKPLQDKGIKVILS 90 Query: 96 IGGGIADKTAYASMASNPTSRKS-FIDSSIRVARSYGFHGLDLDWEYPS-SATEMTNFGT 153 I G + +A+ T+R F Y G+ D EY + + F T Sbjct: 91 ILGNHDR----SGIANLSTARAKAFAQELKNTCDLYNLDGVFFDDEYSAYQTPPPSGFVT 146 Query: 154 LLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDW 202 + + E + P L+ V+ + + S +D+ Sbjct: 147 PSNNAAARLAYETKQA-MPNKLVTVYVYSRTSSFPTAVDGVNAGSYVDY 194 >2GSJ-A nrPDB Length = 271 Score = 35.4 bits (80), Expect = 0.041, Method: Composition-based stats. Identities = 39/175 (22%), Positives = 66/175 (37%), Gaps = 33/175 (18%) Query: 86 RNPSVKTLLSIGGGIADKTAYASMASNPTSR-------KSFI--DSSIRVARSYGFHGLD 136 + +K +LSIGGG + ++S +R +F+ SS R G+D Sbjct: 68 QRRGIKVMLSIGGGAGSYS----LSSVQDARSVADYIWNNFLGGRSSSRPLGDAVLDGVD 123 Query: 137 LDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAV 196 D E+ + + L R +E + GK L AA + A+ Sbjct: 124 FDIEHGGAYYD-----ALARRL-----SEHNRGGKKVFLSAAPQCPFPDQSLN----KAL 169 Query: 197 ASSL-DWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAK 250 ++ L D+V + Y P +G P+ + N S + ++ GLPA Sbjct: 170 STGLFDYVWVQFY--NNPQCEFNSGNPSNFRNSWNKWTSS-FNAKFYV--GLPAS 219 >1F8Q-A nrPDB Length = 263 Score = 34.2 bits (77), Expect = 0.085, Method: Composition-based stats. Identities = 25/125 (20%), Positives = 47/125 (37%), Gaps = 12/125 (9%) Query: 144 SATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFY-SNNYYSVLYPVSAVASSLD- 201 S + ++G +++ R+A+ P LL + + + + ++D Sbjct: 7 SGADPRSYGMFIKDLRNALPFREKVYNIPLLLPSVSGAGRYLLMHLFNRDGKTITVAVDV 66 Query: 202 -WVNLMAY--DFYGPGWSRVTGPPAALFDPSNA------GPSGDAGTRSWIQAGLPAKKA 252 V +M Y D ++ A+ + +A SGD R I AG P +K Sbjct: 67 TNVYIMGYLADTTSYFFNEPAAELASQYVFRDARRKITLPYSGDYE-RLQIAAGKPREKI 125 Query: 253 VLGFP 257 +G P Sbjct: 126 PIGLP 130 >4GUW-A nrPDB Length = 246 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 44/124 (35%), Gaps = 10/124 (8%) Query: 144 SATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFY-SNNYYSVLYPVSAVASSLD- 201 S + +++G +++ R+A+ P LL + + + Y + + ++D Sbjct: 7 SGADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLMHLFNYDGNTITVAVDV 66 Query: 202 -WVNLM-------AYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAV 253 V +M +Y F P + P R I AG P +K Sbjct: 67 TNVYIMGYLALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYERLQIAAGKPREKIP 126 Query: 254 LGFP 257 +G P Sbjct: 127 IGLP 130 >4NUY-A nrPDB Length = 899 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 44/283 (15%), Positives = 82/283 (28%), Gaps = 47/283 (16%) Query: 97 GGGIAD-KTAYASMASNPTSRKSFIDSSIR-VARSYGFHGLDLDWEY---PSSATEMTNF 151 GG + + + P K+ + + Y GLD+D E+ P + Sbjct: 93 GGDNSGIAEDTSKYPNTPEGNKALAKAIVDEYVYKYNLDGLDVDVEHDSIPKVDKKEDTA 152 Query: 152 GT-----LLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLM 206 G + E + + + ++ + + N P ++NL+ Sbjct: 153 GVERSIQVFEEIGKLIGPKGVDKSRLFIMDSTYMADKNPLIERGAP---------YINLL 203 Query: 207 AYDFYGP-----GWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYY-- 259 YG GW V+ P + G S +I+ ++ ++GF +Y Sbjct: 204 LVQVYGSQGEKGGWEPVSNRPEKTMEERWQGYS------KYIR----PEQYMIGFSFYEE 253 Query: 260 ----GYAWRLTNANSHSYYAPTTGAAISPDGSIGYG--QIRKFIVDNG---ATTVYNSTV 310 G W N+ A I+ + Y Q + V G + Sbjct: 254 NAQEGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKTGGVKGGIFSYAIDRDGVA 313 Query: 311 VGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGAD 353 YA + D + Y+ + L D Sbjct: 314 HQPKKYAKQKE--FKDATDNIFHSDYSVSKALKTVMLKDKSYD 354 >3MU7-A nrPDB Length = 273 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 50/259 (19%), Positives = 82/259 (31%), Gaps = 47/259 (18%) Query: 32 YW--FPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPS 89 YW DS + ++ F + + + Q ++ + Sbjct: 8 YWGQSFDERSLEATCDSGNYAYVIIGFLNTFGGGQTPALDISGHSPKGLEPQIKHCQSKN 67 Query: 90 VKTLLSIGGGIADKTAYASMASNPTS------RKSFIDSSIRVARSYGF-----HGLDLD 138 VK LLSIGG Y+ + N + K+F+ + S F G+D Sbjct: 68 VKVLLSIGG---PAGPYSLDSRNDANDLAVYLHKNFLLPPAGTSESRPFGNAVLDGIDFH 124 Query: 139 WEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVAS 198 E+ ++ +L +R SG L AA +YP + + Sbjct: 125 IEH-GGPSQYQLLANILSSFR--------LSGSEFALTAAP--------QCVYPDPNLGT 167 Query: 199 SLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPY 258 +N +D W + P + SNA +A + W K LGFP Sbjct: 168 V---INSATFD---AIWVQFYNNPQCSYSASNASALMNAW-KEWSMK-ARTDKVFLGFPA 219 Query: 259 YGYAWRLTNANSHSYYAPT 277 + +A Y PT Sbjct: 220 H------PDAAGSGYMPPT 232 >4TOQ-A nrPDB Length = 273 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 37/221 (16%), Positives = 66/221 (29%), Gaps = 37/221 (16%) Query: 86 RNPSVKTLLSIGGGIADKTAYASMASNPTSR---KSFI--DSSIRVARSYGFHGLDLDWE 140 + +K L+SIGGG D + + ++ + +F+ SS R G+D D E Sbjct: 68 QGKDIKVLMSIGGGAGDYSLVSEADADNFADYLWNNFLGGQSSSRPLGDAVLDGIDFDIE 127 Query: 141 YPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSL 200 T A+ + ++ + K L AA + + Sbjct: 128 L--------GTTTFYDTLARALSSRSTQAAKVYL--TAAPQCPHP--DSHLDAALNTGLF 175 Query: 201 DWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWI--QAGLPAKKAVLGFP- 257 D V + Y L + + + SW + A K LG P Sbjct: 176 DNVWIQFY-------------NNPLAQCQYSSGNTNDILSSWNTWTSSTTAGKIFLGLPA 222 Query: 258 ---YYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRK 295 G + + + P + G + Y + Sbjct: 223 APEAAGSGYIPPDVLTGQIL-PQIKTSAKYGGVMLYSKFYD 262 >2BHU-A nrPDB Length = 602 Score = 32.7 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 37/125 (29%), Gaps = 17/125 (13%) Query: 111 SNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSG 170 + P R+ ++ R Y F GL LD P + + + E G Sbjct: 248 AEPHMRRYVTGNARMWLRDYHFDGLRLD-ATPYMTDDSETHIL------TELAQEIHELG 300 Query: 171 KPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSN 230 LLL + L V + LD + DF+ +TG + Sbjct: 301 GTHLLL----AEDHRNLPDLVTV----NHLDGIW--TDDFHHETRVTLTGEQEGYYAGYR 350 Query: 231 AGPSG 235 G Sbjct: 351 GGAEA 355 >3ZR5-A nrPDB Length = 656 Score = 32.3 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 48/141 (34%), Gaps = 17/141 (12%) Query: 70 SANQPKFSTFT----QTVQRRNPSVKTL---LSIGGGIADKTAYASMASNPTSRKSFIDS 122 ++ F + + ++RNP + + S G + ++ N ++ Sbjct: 92 ELDENYFRGYEWWLMKEAKKRNPDIILMGLPWSFPGWLG--KGFSWPYVNLQLTAYYVVR 149 Query: 123 SIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFY 182 I A+ Y H LD+D Y E ++E R + G R+ + A+ Sbjct: 150 WILGAKHY--HDLDID--YIGIWNERPFDANYIKELRKMLD----YQGLQRVRIIASDNL 201 Query: 183 SNNYYSVLYPVSAVASSLDWV 203 S L + +D + Sbjct: 202 WEPISSSLLLDQELWKVVDVI 222 >1CEO-A nrPDB Length = 343 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 25/60 (41%), Gaps = 6/60 (10%) Query: 89 SVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSS-IRVARSYGFHGLDLDWEYPSSATE 147 S K +++GG I+ ++ +FI I GF + L ++YP ++ Sbjct: 3 SFKAGINLGGWISQYQVFSK-----EHFDTFITEKDIETIAEAGFDHVRLPFDYPIIESD 57 >5KEG-A nrPDB Length = 203 Score = 31.2 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 11/26 (42%) Query: 203 VNLMAYDFYGPGWSRVTGPPAALFDP 228 V++M YD + W A F P Sbjct: 154 VSIMTYDEFKHCWDTFVDHQGAPFQP 179 >4TXE-A nrPDB Length = 294 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 50/181 (27%), Gaps = 47/181 (25%) Query: 91 KTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRV------ARSYGF-----HGLDLDW 139 K LLS+GG + + S+ + ++F + A F G D D Sbjct: 81 KVLLSLGGASG-----SYLFSDDSQAETFAQTLWDTFGEGTGASERPFDSAVVDGFDFDI 135 Query: 140 EYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASS 199 E + L + R+ G + L+AA SV + Sbjct: 136 E----NNNEVGYSALATKLRTLFAE-----GTKQYYLSAAPQCPYPDASVGDLLENAD-- 184 Query: 200 LDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAK---KAVLGF 256 +D+ + Y + + + D + K LG Sbjct: 185 IDFAFIQFY---------------NNYCSVSGQFNWDTWLTY--AQTVSPNKNIKLFLGL 227 Query: 257 P 257 P Sbjct: 228 P 228 >2XVP-A nrPDB Length = 310 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 34/185 (18%), Positives = 51/185 (27%), Gaps = 44/185 (23%) Query: 91 KTLLSIGG-----------------GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFH 133 K LLSIGG A+ +A + F D + Sbjct: 89 KVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVV--------D 140 Query: 134 GLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV 193 G D D E+ + T++ +R + L AA + Sbjct: 141 GFDFDIEHNGGFG----YATMVNTFRQYFNQV---PERKFYLSAAPQCIIPD-------- 185 Query: 194 SAVASSLDWVNLMAYDFYGPGWSRVTGPPAALF-DPSNAGPSGDAGTRSWIQAGLPAKKA 252 A D + A+DF + A F D S + DA + K Sbjct: 186 ---AQLSDAIFNAAFDFIWIQYYNTAACSAKSFIDTSLGTFNFDAWVTVLKASASKDAKL 242 Query: 253 VLGFP 257 +G P Sbjct: 243 YVGLP 247 >6MSO-A nrPDB Length = 585 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/109 (14%), Positives = 36/109 (33%), Gaps = 17/109 (15%) Query: 145 ATEMTNFGTL--LREWR---SAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASS 199 A++ F L L+ + ++ +G A + + + A++ Sbjct: 124 ASDNDKFVALQLLKNANISSARLLPGCQDTGTA----IIAGYRGDQVFVPGNDEEALSRG 179 Query: 200 LDWVNLMAYD-FYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGL 247 + YD F + P +++D N G + A + G+ Sbjct: 180 V-------YDIFQKRNFRYSQNVPLSMYDEKNTGTNLPAQIDLYASKGM 221 >3HDH-A nrPDB Length = 302 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 41/127 (32%), Gaps = 19/127 (14%) Query: 108 SMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFG---TLLREWRSAVVA 164 + P + + ++S + +++ G ++P S + F L+ AV Sbjct: 170 EVVKTPMTSQKTLESLVDFSKTLG--------KHPVSCKDTPGFIVNRLLVPYLIEAVRL 221 Query: 165 EASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAA 224 + A YP+ LD+V L F GW + Sbjct: 222 YERGDASKEDIDTA------MKLGAGYPM-GPFELLDYVGLDTTKFIIDGWHEMDS-QNP 273 Query: 225 LFDPSNA 231 LF PS A Sbjct: 274 LFQPSPA 280 >4HNS-A nrPDB Length = 124 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 31/89 (34%), Gaps = 11/89 (12%) Query: 122 SSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEA------SSSGKPRLL 175 +++ + + F + DW P LL+ R+ + ++ K + Sbjct: 40 TALPMLKKGDFDFVVTDWNMPGMQG-----IDLLKNIRADEELKHLPVLMITAEAKREQI 94 Query: 176 LAAAVFYSNNYYSVLYPVSAVASSLDWVN 204 + AA N Y + + + LD + Sbjct: 95 IEAAQAGVNGYIVKPFTAATLKEKLDKIF 123 >6Q64-A nrPDB Length = 364 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 27/181 (14%), Positives = 51/181 (28%), Gaps = 37/181 (20%) Query: 113 PTSRKSFIDSSIRVA-------RSYGFHGLDLDWEYPS-------------SATEMTNFG 152 + +FI+ A Y G D+D++ P S + Sbjct: 156 EKGQGNFIEGVKAYANAICDSIEKYNLDGFDIDYQ-PGYGHSGTLANYQTISPSGNNKMQ 214 Query: 153 TLLREWRSAVVAEAS---SSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVN----- 204 + + + G+P LL ++Y Y S+ +S + +N Sbjct: 215 VFIETLSARLRPAGRMLVMDGQPDLLSTETSKLVDHYIYQAYWESSTSSVIYKINKPNLD 274 Query: 205 ------LMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPY 258 ++ +F GW + G + LP+ K + G Sbjct: 275 DWERKTIITVEFE-QGW-KTGGITYYTSVRPELNSMEGNQILDYATLDLPSGKRIGGIGT 332 Query: 259 Y 259 Y Sbjct: 333 Y 333 >3V6B-R nrPDB Length = 424 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 23/74 (31%), Gaps = 13/74 (17%) Query: 134 GLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV 193 G+D +WEYPSS + R S K L + LY Sbjct: 125 GIDFNWEYPSSKHQHKKLVN-----RDLKTQSGSEMKK--FLSTLTIDGVTRSDQGLYTC 177 Query: 194 SAVASSLDWVNLMA 207 +A + LM Sbjct: 178 AASSG------LMT 185 >3V2A-R nrPDB Length = 772 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 23/74 (31%), Gaps = 13/74 (17%) Query: 134 GLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV 193 G+D +WEYPSS + R S K L + LY Sbjct: 255 GIDFNWEYPSSKHQHKKLVN-----RDLKTQSGSEMKK--FLSTLTIDGVTRSDQGLYTC 307 Query: 194 SAVASSLDWVNLMA 207 +A + LM Sbjct: 308 AASSG------LMT 315 >3S35-X nrPDB Length = 122 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 23/74 (31%), Gaps = 13/74 (17%) Query: 134 GLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV 193 G+D +WEYPSS + R S K L + LY Sbjct: 39 GIDFNWEYPSSKHQHKKLVN-----RDLKTQSGSEMKK--FLSTLTIDGVTRSDQGLYTC 91 Query: 194 SAVASSLDWVNLMA 207 +A + LM Sbjct: 92 AASSG------LMT 99 >2X1X-R nrPDB Length = 213 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 23/74 (31%), Gaps = 13/74 (17%) Query: 134 GLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPV 193 G+D +WEYPSS + R S K L + LY Sbjct: 136 GIDFNWEYPSSKHQHKKLVN-----RDLKTQSGSEMKK--FLSTLTIDGVTRSDQGLYTC 188 Query: 194 SAVASSLDWVNLMA 207 +A + LM Sbjct: 189 AASSG------LMT 196 >4WP0-A nrPDB Length = 472 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Query: 39 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTV-QRRNPSVKTLLSIG 97 FP D F H LN T + S F + + Q +P L+++G Sbjct: 40 FPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVG 99 Query: 98 GGIADKTAYASMA 110 G A TA+ ++ Sbjct: 100 GYGALFTAFQALV 112 >3FVS-A nrPDB Length = 422 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Query: 39 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTV-QRRNPSVKTLLSIG 97 FP D F H LN T + S F + + Q +P L+++G Sbjct: 40 FPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVG 99 Query: 98 GGIADKTAYASMA 110 G A TA+ ++ Sbjct: 100 GYGALFTAFQALV 112 >1LFW-A nrPDB Length = 470 Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 54/189 (28%), Gaps = 29/189 (15%) Query: 110 ASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNF----------GTLLREWR 159 AS P K+ Y F G D ++ + + E +F L+ + Sbjct: 270 ASAPQVGKNSATFLALFLDQYAFAGRDKNFLHFLAEVEHEDFYGKKLGIFHHDDLMGDLA 329 Query: 160 S---AVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWS 216 S E + GK LL + Y P + + LD F G Sbjct: 330 SSPSMFDYEHA--GKASLL------NNVRYPQGTDPDTMIKQVLDK-------FSGILDV 374 Query: 217 RVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAW-RLTNANSHSYYA 275 G + P + Q G P + V+G YG + R + Sbjct: 375 TYNGFEEPHYVPGSDPMVQTLLKVYEKQTGKPGHEVVIGGGTYGRLFERGVAFGAQPENG 434 Query: 276 PTTGAAISP 284 P A + Sbjct: 435 PMVMHAANE 443 >5OT1-A nrPDB Length = 765 Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 38/123 (30%), Gaps = 15/123 (12%) Query: 43 DIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIAD 102 D + AF D+ + N+ K F +G Sbjct: 418 DFVPNHCGIGNPAFLDVWEKGNESPYWDWFFVKKWPFKLGDGSAY--------VGWWGFG 469 Query: 103 KTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAV 162 +N R+ I +++ +GF G+ +D E+ + GT E R AV Sbjct: 470 SLP-KLNTANQEVREYLIGAALHWI-EFGFDGIRVD-----VPNEVLDPGTFFPELRKAV 522 Query: 163 VAE 165 + Sbjct: 523 KEK 525 >3ML1-A nrPDB Length = 802 Score = 29.2 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 27/85 (31%), Gaps = 9/85 (10%) Query: 58 DLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGI---------ADKTAYAS 108 D N VT A F + ++ + P+ + G K + S Sbjct: 83 DKNGDFAPVTWDQAFDEMERQFKRVLKEKGPTAVGMFGSGQWTVWEGYAAAKLYKAGFRS 142 Query: 109 MASNPTSRKSFIDSSIRVARSYGFH 133 +P +R ++ R++G Sbjct: 143 NNIDPNARHCMASAAAGFMRTFGMD 167 >2NYA-A nrPDB Length = 792 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 23/77 (29%), Gaps = 9/77 (11%) Query: 66 VTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGI---------ADKTAYASMASNPTSR 116 +T A F ++ + P + G K + S +P +R Sbjct: 82 ITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRSNNIDPNAR 141 Query: 117 KSFIDSSIRVARSYGFH 133 + + R++G Sbjct: 142 HCMASAVVGFMRTFGMD 158 >6IBP-A nrPDB Length = 420 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 29/80 (36%), Gaps = 3/80 (3%) Query: 60 NSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSF 119 + + +S + FT +K + GG K +P R F Sbjct: 133 RPDSVEFVLSLEEDLRRRDFTINAMAMTEDLKIIDPFGGKEDLKNKVIRAVGDPDER--F 190 Query: 120 IDSSIRVARSYGFHGLDLDW 139 + ++R+ R+ F G LD+ Sbjct: 191 EEDALRMLRAIRFSG-QLDF 209 >3K4O-A nrPDB Length = 266 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 20/70 (28%), Gaps = 5/70 (7%) Query: 57 ADLNSQTNQVTVSSANQPK-----FSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMAS 111 + S N + + + +N +K +L GGG Sbjct: 15 GSILSDKNVPYSIKWDNLERIAMEIKNALDYYKNQNKEIKLILVHGGGAFGHPVAKKYLK 74 Query: 112 NPTSRKSFID 121 +K FI+ Sbjct: 75 IEDGKKIFIN 84 >5E9A-A nrPDB Length = 712 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 30/101 (29%), Gaps = 14/101 (13%) Query: 129 SYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYS 188 G HGL+LDW E + AE A + Y Sbjct: 237 ENGVHGLNLDW----RRFNTDQVTRFCSEEIRPLKAENP---------ALPATTNFMEYF 283 Query: 189 VLYPVSAVASSLDWVNLMAYD-FYGPGWSRVTGPPAALFDP 228 Y +A LD+++ +Y ++ A++ Sbjct: 284 NDYDYWKLAGVLDFISWDSYPMWHTRQDDIGLAAYTAMYHD 324 >4AEF-A nrPDB Length = 645 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 12/63 (19%) Query: 82 TVQRRNPSVKTLLSIGGGIADKTAYASMA------SNPTSRKSFIDSSIRVARSYGFHGL 135 + + + +K+L G + ++ NP R+ FI + I + G G Sbjct: 355 SWEEKYKKIKSL----GWNYES-FFSVWIMPRLNHDNPKVRE-FIKNVILFWTNKGVDGF 408 Query: 136 DLD 138 +D Sbjct: 409 RMD 411 >6IDN-A nrPDB Length = 272 Score = 28.1 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 49/258 (18%), Positives = 70/258 (27%), Gaps = 66/258 (25%) Query: 86 RNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFI-------DSSIRVARSYGFHGLDLD 138 ++ +K LS+GGG Y S + S ++ S R G+D D Sbjct: 68 KSKGIKVFLSLGGGTG--NYYLSSRDDAASVAQYLWNNFLGGQSESRPLGDESLDGIDFD 125 Query: 139 WEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVAS 198 E + TL + SG L AA +YY A+ + Sbjct: 126 IE----DGSNDYYDTL----AEQLWILGGRSGSNVYLAAAPACEFPDYYLR----EAINT 173 Query: 199 SL-DWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFP 257 SL D+V + FY G L SW Sbjct: 174 SLFDYVWVQ---FYNNPRCHYLGNATNL-------------LNSWNN------------- 204 Query: 258 YYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYA 317 W + P A G I + ++ T+ Y Y Sbjct: 205 ----DWSTILTDDLFLGLPAAPQAAPGGGFIEADDLISEVL---------PTIKATYDYG 251 Query: 318 GTNWIG--YDDNQSIVTK 333 G YDD+ S K Sbjct: 252 GVMLWSKYYDDDYSSKIK 269 >1KQY-A nrPDB Length = 273 Score = 28.1 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 10/28 (35%) Query: 338 KQRGLLGYFSWHVGADDNSGLSRAASQA 365 K G W DD +G S + + Sbjct: 245 KSPKYGGVMLWSKFYDDKNGYSSSILDS 272 >4J3X-A nrPDB Length = 905 Score = 28.1 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 17/58 (29%), Gaps = 4/58 (6%) Query: 244 QAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNG 301 G+ K L YG W + + +S G + + ++ G Sbjct: 517 AHGVDGSKIYL----YGAGWDFAEVARNQRGINGSQLNMSGTGIGSFNDRIRDAINGG 570 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.136 0.392 Lambda K H 0.267 0.0415 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,851,841 Number of Sequences: 36641 Number of extensions: 597722 Number of successful extensions: 2334 Number of sequences better than 10.0: 101 Number of HSP's better than 10.0 without gapping: 116 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 1741 Number of HSP's gapped (non-prelim): 199 length of query: 379 length of database: 10,336,785 effective HSP length: 99 effective length of query: 280 effective length of database: 6,709,326 effective search space: 1878611280 effective search space used: 1878611280 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)