BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O80944 (311 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3H7R-A nrPDB 644 0.0 3H7U-A nrPDB 429 e-121 5JH1-A nrPDB 389 e-108 2BGQ-A nrPDB 256 8e-69 1HQT-A nrPDB 243 7e-65 2ALR-A nrPDB 241 2e-64 4GAC-A nrPDB 240 5e-64 1Q5M-A nrPDB 224 5e-59 4JQA-A nrPDB 222 1e-58 1ZUA-X nrPDB 221 4e-58 5Z6T-A nrPDB 218 3e-57 5JM5-A nrPDB 215 2e-56 5ZCM-A nrPDB 213 6e-56 4HBK-A nrPDB 212 2e-55 3G1R-A nrPDB 210 5e-55 1VP5-A nrPDB 210 8e-55 2FVL-A nrPDB 207 3e-54 1K8C-A nrPDB 207 6e-54 4GIE-A nrPDB 205 2e-53 1DLA-A nrPDB 199 1e-51 1VBJ-A nrPDB 198 2e-51 3RX4-A nrPDB 198 3e-51 2HE8-A nrPDB 195 3e-50 4F40-A nrPDB 193 6e-50 1QWK-A nrPDB 193 7e-50 1FRB-A nrPDB 193 9e-50 1AFS-A nrPDB 192 1e-49 4MHB-A nrPDB 191 2e-49 3O3R-A nrPDB 191 3e-49 1C9W-A nrPDB 191 5e-49 5UXF-A nrPDB 189 2e-48 3KRB-A nrPDB 188 2e-48 3WCZ-A nrPDB 187 6e-48 1MZR-A nrPDB 187 7e-48 3D3F-A nrPDB 184 6e-47 4IJC-A nrPDB 167 4e-42 1A80-A nrPDB 166 2e-41 4OTK-A nrPDB 163 1e-40 3UP8-A nrPDB 162 2e-40 3WG6-A nrPDB 142 2e-34 4H8N-A nrPDB 126 1e-29 1PZ1-A nrPDB 81 5e-16 1OG6-A nrPDB 61 6e-10 1PYF-A nrPDB 60 8e-10 3N6Q-A nrPDB 59 2e-09 3EB3-A nrPDB 59 4e-09 4R9O-A nrPDB 56 2e-08 1LQA-A nrPDB 55 4e-08 1GVE-A nrPDB 40 0.001 2CLP-A nrPDB 38 0.007 2BP1-A nrPDB 37 0.015 2C91-A nrPDB 35 0.033 6NBX-H nrPDB 30 1.9 3B0X-A nrPDB 28 6.2 2NZ0-B nrPDB 28 7.4 >3H7R-A nrPDB Length = 331 Score = 644 bits (1662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/311 (100%), Positives = 311/311 (100%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK Sbjct: 21 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 80 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 120 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL Sbjct: 81 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 140 Query: 121 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH 180 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH Sbjct: 141 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH 200 Query: 181 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR 240 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR Sbjct: 201 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR 260 Query: 241 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY 300 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY Sbjct: 261 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY 320 Query: 301 KTIEELWDGEI 311 KTIEELWDGEI Sbjct: 321 KTIEELWDGEI 331 >3H7U-A nrPDB Length = 335 Score = 429 bits (1104), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/315 (66%), Positives = 243/315 (77%), Gaps = 4/315 (1%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 56 MA I FF+LNTGAK P VGLGT+ +V A+ A+KIGYRHIDCA IYGNEKEIG Sbjct: 21 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 80 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 VLKKL D VKRE+LFITSKLW DH P+DVP+AL +TL+DLQ++YVDLYLIHWPA +K Sbjct: 81 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 140 Query: 117 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQ 176 K S+ PE L DI STWKAMEALYDSGKARAIGVSNFS+KKL DLL +ARV PAVNQ Sbjct: 141 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 200 Query: 177 VECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQ 236 VECHP W+Q L E CKSKGVHLS YSPLGS ++ VL+NPI+ VAEKLGK+ AQ Sbjct: 201 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 260 Query: 237 VALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHET 296 VALRWGLQ GHSVLPKS++ R+KEN +VFDWSIP+ +F KF+ I Q + + HET Sbjct: 261 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 320 Query: 297 HGFYKTIEELWDGEI 311 YK+IEELWDGEI Sbjct: 321 LSPYKSIEELWDGEI 335 >5JH1-A nrPDB Length = 309 Score = 389 bits (998), Expect = e-108, Method: Compositional matrix adjust. Identities = 190/310 (61%), Positives = 229/310 (73%), Gaps = 6/310 (1%) Query: 6 RFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKL 61 R F LNTGAK+P VGLG++ +V A+ A+K GYRHIDCA +YGNEKEIG LKKL Sbjct: 2 RHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKKL 61 Query: 62 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLM 121 +G VKRE++FITSKLW++ H PEDVP+AL +L DLQ++Y+DLYLIHWP +KK + Sbjct: 62 FEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGT-N 120 Query: 122 PTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHP 181 +PE PD +TW AME LYD+GKARAIGVSNFSSKKL DLL VARV PAV+QVECHP Sbjct: 121 TSPENFVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVARVPPAVDQVECHP 180 Query: 182 VWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRW 241 WQQ LH C+S GVHL+ YSPLGS + VL+ PI+ +AEKLGKT+AQVALRW Sbjct: 181 GWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGNVLKEPIIISIAEKLGKTSAQVALRW 240 Query: 242 GLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFYK 301 +Q GHSVLPKS++ R+K+NLDV+DWSIP+DL KFS I Q + R F YK Sbjct: 241 NIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEIKQARLLRGN-FIVNPESVYK 299 Query: 302 TIEELWDGEI 311 T EELWDGE+ Sbjct: 300 THEELWDGEL 309 >2BGQ-A nrPDB Length = 344 Score = 256 bits (654), Expect = 8e-69, Method: Compositional matrix adjust. Identities = 141/314 (44%), Positives = 190/314 (60%), Gaps = 21/314 (6%) Query: 8 FELNTGAKLPCVGLGTYAM-------VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 F L +G +P VGLGT+ V TAI +A GYRH+D A+ YG EKE+G LK Sbjct: 40 FVLKSGHAMPAVGLGTWRAGSDTAHSVRTAITEA---GYRHVDTAAEYGVEKEVGKGLKA 96 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 120 + G + R++LF+TSK+W + PE V ALE TL+DLQ+DY+DLY IHWP LK + Sbjct: 97 AMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAH 155 Query: 121 MPTPEM--LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVE 178 MP PE + + D+ WK ME L G + IGV N++ KL LL A++ PAV Q+E Sbjct: 156 MP-PEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQME 214 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVA 238 HP W+ + E CK G+H++ YSPLGS K + +P+V +VA KL KT QV Sbjct: 215 MHPGWKNDKIFEACKKHGIHITAYSPLGSSEKN-----LAHDPVVEKVANKLNKTPGQVL 269 Query: 239 LRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATE--FAHET 296 ++W LQ G SV+PKSS R+KEN+ VF W IPE+ F +I EK E F ++T Sbjct: 270 IKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFVNKT 329 Query: 297 HGFYKTIEELWDGE 310 HG Y++ ++WD E Sbjct: 330 HGPYRSARDVWDHE 343 >1HQT-A nrPDB Length = 326 Score = 243 bits (621), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 129/280 (46%), Positives = 185/280 (66%), Gaps = 16/280 (5%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 L+TG K+P +GLGT+ V AI+ A+ +GYRHIDCA+I+GNE EIG L++ +G G Sbjct: 9 LHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQETVGPG 68 Query: 66 -FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124 V REELF+TSKLW+ H PEDV AL KTL DLQ++Y+DLYL+HWP + ++ P P Sbjct: 69 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD-NPFP 127 Query: 125 ---EMLTKPDIT---STWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVE 178 + + D T TWKA+EAL G RA+G+SNFSS+++ D+L+VA V PAV QVE Sbjct: 128 KNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVE 187 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKG---EVRLKVLQNPIVTEVAEKLGKTTA 235 CHP Q L C+++G+ ++ YSPLGS + +L+ P+V +AEK ++ A Sbjct: 188 CHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPA 247 Query: 236 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDL 274 Q+ LRW +Q +PKS + +R+ +N+ VFD++ PE++ Sbjct: 248 QILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEM 287 >2ALR-A nrPDB Length = 324 Score = 241 bits (616), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 127/280 (45%), Positives = 183/280 (65%), Gaps = 16/280 (5%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 L+TG K+P +GLGT+ V A++ A+ +GYRHIDCA+IYGNE EIG LK+ +G G Sbjct: 7 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 66 Query: 66 -FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124 V REELF+TSKLW+ H PEDV AL KTL DLQ++Y+DLYL+HWP + ++ P P Sbjct: 67 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD-NPFP 125 Query: 125 E------MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVE 178 + TWKA+EAL G +A+G+SNF+S+++ D+L+VA V PAV QVE Sbjct: 126 KNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 185 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKG---EVRLKVLQNPIVTEVAEKLGKTTA 235 CHP Q L C+++G+ ++ YSPLGS + +L+ P+V +AEK G++ A Sbjct: 186 CHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPA 245 Query: 236 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDL 274 Q+ LRW +Q +PKS + +R+ +N+ VFD++ PE++ Sbjct: 246 QILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEM 285 >4GAC-A nrPDB Length = 324 Score = 240 bits (613), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 129/280 (46%), Positives = 183/280 (65%), Gaps = 16/280 (5%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 L+TG K+P +GLGT+ V AI+ A+ GYRHIDCAS+YGNE EIG LK+ +G G Sbjct: 7 LHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSG 66 Query: 66 -FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124 V REELF+TSKLW+ H PEDV AL KTL DLQ++Y+DLYL+HWP + ++ P P Sbjct: 67 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD-NPFP 125 Query: 125 ---EMLTKPDIT---STWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVE 178 + + D T TWKA+E L G +A+G+SNF+S+++ D+L+VA V PAV QVE Sbjct: 126 KNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVE 185 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGKTTA 235 CHP Q L C ++G+ ++ YSPLGS + +L+ P+V +AEK G++ A Sbjct: 186 CHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPA 245 Query: 236 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDL 274 Q+ LRW +Q +PKS + +R+ +N+ VFD++ PE++ Sbjct: 246 QILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEM 285 >1Q5M-A nrPDB Length = 322 Score = 224 bits (570), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 129/286 (45%), Positives = 178/286 (62%), Gaps = 23/286 (8%) Query: 10 LNTGAKLPCVGLGTYA---------MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 L+ G +P +G GTYA M AT I AI G+RHID A Y NEKE+G ++ Sbjct: 9 LSDGHFIPVLGFGTYAPEEVPKSKAMEATKI--AIDAGFRHIDSAYFYKNEKEVGLAIRS 66 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-S 119 I DG VKRE++F TSKLW H PE V +LE +L++LQ+DYVDLY+IH+P +LK Sbjct: 67 KIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVE 126 Query: 120 LMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPA 173 ++PT E + DI +TW+AME D+G A++IGVSNF+ ++L +LN + P Sbjct: 127 IIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 186 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGE----VRLKVLQNPIVTEVAEK 229 NQVECHP Q L E CKSKG+ L YS LGS + E +L++P++ +A+K Sbjct: 187 CNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKK 246 Query: 230 LGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIP-EDL 274 +T A +ALR+ LQ G VL KS + R+KEN+ VF++ +P ED+ Sbjct: 247 HQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDM 292 >4JQA-A nrPDB Length = 331 Score = 222 bits (566), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 120/288 (41%), Positives = 180/288 (62%), Gaps = 18/288 (6%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYAMVAT-------AIEQAIKIGYRHIDCASIYGNEKE 53 M + + +LN G +P +G GTYA A++ AI+ G+ HID A +Y NE++ Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 +G ++ I DG VKRE++F TSKLWSN H PE V ALE++L++LQ+DYVDLYLIH+P Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 114 SLKK-ESLMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 S+K E ++P E + D+ +TW+AME D+G A++IGVSNF+ + L +LN Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSK----GEVRLKVLQNPI 222 + P NQVECHP + Q+ L + CKSK + L YS LGS + +L++P+ Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 + +A+K +T A +ALR+ LQ G VL KS + R+++N+ VF++ + Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQL 288 >1ZUA-X nrPDB Length = 317 Score = 221 bits (562), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 127/303 (41%), Positives = 180/303 (59%), Gaps = 15/303 (4%) Query: 7 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA +Y NE E+G +++ I Sbjct: 5 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 64 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 121 + VKRE+LFI SKLW V KA EKTL+DL++ Y+D+YLIHWP K + L Sbjct: 65 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 124 Query: 122 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P + + K W+AME L D G +A+GVSNFS ++ LLN + P N Sbjct: 125 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 184 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 232 QVECHP Q+ L + C SKG+ ++ YSPLGS + + + +L++P + E+A K K Sbjct: 185 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 244 Query: 233 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIP-EDLFTKFSNIPQEKFCRATE 291 T AQV +R+ +Q V+PKS + AR+ EN+ VFD+ + E++ T S + C + Sbjct: 245 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQ 304 Query: 292 FAH 294 +H Sbjct: 305 SSH 307 >5Z6T-A nrPDB Length = 343 Score = 218 bits (555), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 129/295 (43%), Positives = 172/295 (58%), Gaps = 22/295 (7%) Query: 9 ELNTGAKLPCVGLGTYAM-VATAIEQ---AIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64 +LN+G +P VG G + + V T EQ AIK GYR D A Y NEK +G +KK I + Sbjct: 30 KLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDE 89 Query: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK---KESLM 121 G VKRE+LF+TSKLW+N H P++V KAL +TL DLQ+DYVDL+LIH+P + K E Sbjct: 90 GIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKY 149 Query: 122 PTPEMLTKPD--------ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPA 173 P K D I TWKA+E L +GK R+IGVSNF L DLL A + P+ Sbjct: 150 PPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPS 209 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRL-------KVLQNPIVTEV 226 V QVE HP QQ L E +S+G+ ++ YS G QS E+ + +N + + Sbjct: 210 VLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAI 269 Query: 227 AEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNI 281 A K GK+ AQV LRW Q G +++PKS++ RL EN DV + + E F + + Sbjct: 270 AAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKL 324 >5JM5-A nrPDB Length = 332 Score = 215 bits (547), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 120/280 (42%), Positives = 171/280 (61%), Gaps = 18/280 (6%) Query: 9 ELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKL 61 +LN G +P +G GTYA + AI+ G+RHID A +Y NE+++G ++ Sbjct: 9 KLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSK 68 Query: 62 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESL 120 I DG VKRE++F TSKLWS H PE V ALE +L+ Q+DYVDLYLIH P SLK E L Sbjct: 69 IADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEEL 128 Query: 121 MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAV 174 PT E + D+ +TW+AME D+G A++IGVSNF+ ++L +LN + P Sbjct: 129 SPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC 188 Query: 175 NQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGE----VRLKVLQNPIVTEVAEKL 230 NQVECHP + + L + CKSK + L YS LGSQ +L++P++ +A+K Sbjct: 189 NQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKH 248 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 +T A +ALR+ LQ G VL KS + R+++N+ VF++ + Sbjct: 249 KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQL 288 >5ZCM-A nrPDB Length = 341 Score = 213 bits (543), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 122/298 (40%), Positives = 179/298 (60%), Gaps = 22/298 (7%) Query: 9 ELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64 +LN+G ++P VG G + A A + AIK+GYR D A YGN KEIG + + + + Sbjct: 25 KLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRALDE 84 Query: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK---KESLM 121 G V R+ELFITSKLW++ H P++V AL+K L D+++DY+DL+LIH+P + K E Sbjct: 85 GLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEEKY 144 Query: 122 PTPEMLTKPD--------ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPA 173 P D + TWKAME L GKA++IG+SNFS+ + DLL A + PA Sbjct: 145 PPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLRGAEIKPA 204 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVR-LKVLQNP------IVTEV 226 V Q+E HP QQ L E +S+G+ ++ YS G QS E++ K L P +T + Sbjct: 205 VLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKTITSI 264 Query: 227 AEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQE 284 A+K KT AQV LRW Q +++PKS++ RL +NL+V D+++ ++ F + S + Q+ Sbjct: 265 ADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLDQD 322 >4HBK-A nrPDB Length = 344 Score = 212 bits (539), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 112/275 (40%), Positives = 168/275 (61%), Gaps = 9/275 (3%) Query: 8 FELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIG 63 ++N G +P +GLGT+ V A+++A++IGYRH+DCA +Y NE EIG L+ + Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 64 DGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLMP 122 +KRE++FITSKLW+ PE V KA E+TL++L+++Y+DLYLIHWP LK L P Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 123 TPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVE 178 T L TWK ME L D G ++IG+SNF+ +++ ++L R+ PA Q+E Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCRIKPANLQIE 217 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVA 238 H + L E +S G+ ++ Y+PLGS + ++ +L P V E+A + KT AQV Sbjct: 218 IHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHSPGKVNLLTKPCVLEIAHRHKKTPAQVL 277 Query: 239 LRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPED 273 LR+ LQ V+PKS + R++EN VFD+ + + Sbjct: 278 LRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNE 312 >3G1R-A nrPDB Length = 346 Score = 210 bits (535), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 111/284 (39%), Positives = 177/284 (62%), Gaps = 21/284 (7%) Query: 10 LNTGAKLPCVGLGTYA--------MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKL 61 L+ G +P +GLGTY+ AT+++ AI GYRHID A IY NE E+G +++ Sbjct: 32 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 91 Query: 62 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESL 120 I +G V+RE++F KLW+ +H+PE V LE+TL+ LQ+DYVDLY+I P + K + + Sbjct: 92 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 151 Query: 121 MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAV 174 P E + K ++ +TW+AMEA D+G +++GVSNF+ ++L +LN + P Sbjct: 152 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVS 211 Query: 175 NQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKV-----LQNPIVTEVAEK 229 NQVECHP + Q L + C+ + ++ YSPLG+ S+ + + V L++ ++ + ++ Sbjct: 212 NQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT-SRNPIWVNVSSPPLLKDALLNSLGKR 270 Query: 230 LGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPED 273 KT AQ+ LR+ +Q G V+PKS + R+KEN +FD+S+ E+ Sbjct: 271 YNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEE 314 >1VP5-A nrPDB Length = 298 Score = 210 bits (534), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 107/278 (38%), Positives = 158/278 (56%), Gaps = 25/278 (8%) Query: 10 LNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 LN G ++P +G G + + + +AIK+GYR ID A+ Y NE+ +G +K+ I +G Sbjct: 20 LNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAIDEG 79 Query: 66 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPE 125 V+REELF+T+KLW +D E KA EK+L+ LQ++Y+DLYLIH P Sbjct: 80 IVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG----------- 128 Query: 126 MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQ 185 D+ WKAME +Y G RAIGVSNF +L DL+ + PAVNQ+E HP +Q+ Sbjct: 129 -----DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQR 183 Query: 186 QGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQT 245 Q E ++ + + P E R + QN ++ +AEK GKT AQV LRW Q Sbjct: 184 QEEIEFMRNYNIQPEAWGPF-----AEGRKNIFQNGVLRSIAEKYGKTVAQVILRWLTQK 238 Query: 246 GHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQ 283 G +PK+ R+KEN+ +FD+ + ++ K + + + Sbjct: 239 GIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDE 276 >2FVL-A nrPDB Length = 324 Score = 207 bits (528), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 114/280 (40%), Positives = 170/280 (60%), Gaps = 18/280 (6%) Query: 9 ELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKL 61 ELN G +P +G GTYA + AI+ G+RHID A +Y NE+++G ++ Sbjct: 10 ELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 69 Query: 62 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESL 120 I DG VKRE++F TSKLW P+ V ALE +L+ LQ+DYVDLYL+H+P +LK E+ Sbjct: 70 IADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETP 129 Query: 121 MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAV 174 +P E + D+++TW+ ME D+G A++IGVSNF+ ++L +LN + P Sbjct: 130 LPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVC 189 Query: 175 NQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSK----GEVRLKVLQNPIVTEVAEKL 230 NQVECHP Q L + CKSK + L +S LG+Q +L++P++ +A+K Sbjct: 190 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKH 249 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 +T A +ALR+ LQ G VL KS + R++EN+ VF++ + Sbjct: 250 KRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQL 289 >1K8C-A nrPDB Length = 322 Score = 207 bits (526), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 127/294 (43%), Positives = 169/294 (57%), Gaps = 30/294 (10%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYAMV-ATAIEQ---AIKIGYRHIDCASIYGNEKEIGG 56 M+A I +L++G +P +G G + + ATA EQ AIK GYR D A YGNEKE+G Sbjct: 1 MSASIPDIKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGD 60 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 +K+ I +G VKREE+F+TSKLW+N H P++V AL KTL DL++DYVDL+LIH+P + K Sbjct: 61 GVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120 Query: 117 KESLMPTPE--------------MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLT 162 +P E + I TWKA+E L +GK ++IGVSNF L Sbjct: 121 ---FVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLL 177 Query: 163 DLLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRL-KVLQNP 221 DLL A + PAV QVE HP QQ L E + GV ++ YS G QS E+ + L P Sbjct: 178 DLLRGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTP 237 Query: 222 ------IVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKEN--LDVFD 267 + +A K KT A+V LRW Q G +V+PKS+ RL +N + FD Sbjct: 238 TLFAHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFD 291 >4GIE-A nrPDB Length = 290 Score = 205 bits (521), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 106/281 (37%), Positives = 166/281 (59%), Gaps = 28/281 (9%) Query: 10 LNTGAKLPCVGLGTY-----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64 L+ ++P +GLG + A A A+ AI+ GYRHID A IY NE+ +G + I + Sbjct: 18 LHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVG----QGIRE 73 Query: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124 V REE+++T+K+W++D E A E++ + L ++Y+DLYLIHWP Sbjct: 74 SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPG----------- 122 Query: 125 EMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQ 184 K TWKA+E LY+ K RAIGVSNF LT+L ++ P VNQVE HP++Q Sbjct: 123 ----KKKFVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFKSCKIRPMVNQVELHPLFQ 178 Query: 185 QQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQ 244 Q+ L E CK + ++ +SPLGS + +L+N ++ E+A+K K+ AQV +RW +Q Sbjct: 179 QRTLREFCKQHNIAITAWSPLGSGEEA----GILKNHVLGEIAKKHNKSPAQVVIRWDIQ 234 Query: 245 TGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEK 285 G +PKS++ R++EN +V+D+ + E+ + + ++K Sbjct: 235 HGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDK 275 >1DLA-A nrPDB Length = 314 Score = 199 bits (507), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 131/309 (42%), Positives = 184/309 (59%), Gaps = 18/309 (5%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 L TGAK+P +GLGT+ V A++ AI +GYRHIDCA +Y NE E+G L++ + Sbjct: 5 LYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQ 64 Query: 66 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP- 124 VKRE+LFI SKLW DH V A + TL+DL++DY+DLYLIHWP K P P Sbjct: 65 VVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKP-GKDPFPL 123 Query: 125 -----EMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVNQV 177 + + D TW+AME L D G +AIGVSNF+ ++ +LN + PAVNQ+ Sbjct: 124 DGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQI 183 Query: 178 ECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGKTT 234 E HP Q+ L E CKSKG+ ++ YSPLGS + + + +L++P + +A K KTT Sbjct: 184 EVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTT 243 Query: 235 AQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFTKFSNIPQEKFCRATEFA 293 AQV +R+ +Q V+PKS + R+ EN VFD+ + PED+ T S + C A Sbjct: 244 AQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMSCA 303 Query: 294 -HETHGFYK 301 H+ + F++ Sbjct: 304 SHKDYPFHE 312 >1VBJ-A nrPDB Length = 281 Score = 198 bits (504), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 111/273 (40%), Positives = 154/273 (56%), Gaps = 32/273 (11%) Query: 8 FELNTGAKLPCVGLGTYAM-----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 +L+ G +P +G G + + TA AIK GYRHID A+IY NE+ G + I Sbjct: 12 LKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAG----RAI 67 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMP 122 V REELF+T+KLW++D E A EK+++ L ++YVDLYLIHWP Sbjct: 68 ASCGVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPG--------- 118 Query: 123 TPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPV 182 K TWKA E LY K RAIGVSNF + +LL +V P VNQ+E HP+ Sbjct: 119 ------KDKFIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKHCKVAPMVNQIELHPL 172 Query: 183 WQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWG 242 Q+ L E CKSK + ++ +SPLG ++++ + + K GKT AQV LRW Sbjct: 173 LNQKALCEYCKSKNIAVTAWSPLGQGH-------LVEDARLKAIGGKYGKTAAQVMLRWE 225 Query: 243 LQTGHSVLPKSSSGARLKENLDVFDWSI-PEDL 274 +Q G +PKS + AR+KEN ++FD+ + ED+ Sbjct: 226 IQAGVITIPKSGNEARIKENGNIFDFELTAEDI 258 >3RX4-A nrPDB Length = 336 Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 124/293 (42%), Positives = 178/293 (60%), Gaps = 15/293 (5%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 LN GAK+P +GLGT+ V A++ AI +GYRHIDCA +Y NE E+G +++ + + Sbjct: 27 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 86 Query: 66 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLMPTP 124 VKREELFI SKLW H V A +KTL DL++DY+DLYLIHWP K + P Sbjct: 87 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 146 Query: 125 E----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVNQVE 178 E + + +I TW AME L D G +AIG+SNF+ ++ +LN + PAVNQ+E Sbjct: 147 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 206 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGKTTA 235 CHP Q+ L + C+SKG+ ++ YSPLGS + + + +L++P + +A K KTTA Sbjct: 207 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 266 Query: 236 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFTKFSNIPQEKFC 287 QV +R+ +Q V+PKS + R+ EN VFD+ + +D+ T S + C Sbjct: 267 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVC 319 >2HE8-A nrPDB Length = 323 Score = 195 bits (495), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 110/279 (39%), Positives = 158/279 (56%), Gaps = 18/279 (6%) Query: 10 LNTGAKLPCVGLGTY-------AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 LN G +P +G GT + + AI G+ H D AS+Y E +G ++ I Sbjct: 10 LNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKI 69 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 121 DG V+RE++F TSK+W PE V +LE++LQ LQ DYVDLYLIH+P +LK E Sbjct: 70 ADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENF 129 Query: 122 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P E + + D+ +TW+AME D+G ++IGVSNF+ ++L +LN + P N Sbjct: 130 PVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCN 189 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKG----EVRLKVLQNPIVTEVAEKLG 231 QVECHP Q L + CKSK + L Y LG+Q G + +L P++ +A+K Sbjct: 190 QVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYN 249 Query: 232 KTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 +T A +ALR+ LQ G VL S R+KEN+ VF++ + Sbjct: 250 RTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQL 288 >4F40-A nrPDB Length = 288 Score = 193 bits (491), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 110/275 (40%), Positives = 154/275 (56%), Gaps = 28/275 (10%) Query: 10 LNTGAKLPCVGLGTYAMVA-----TAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64 L+ G K+P GLG + A A++ A+ GYRHID A+IY NE+ +G L+ Sbjct: 15 LSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA---- 70 Query: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124 V RE++FIT+KLW+ + E A E++ Q L +DY+DLYLIHWP Sbjct: 71 SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG---------K 121 Query: 125 EMLTK--PDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPV 182 ++L+K +W+A E LY K RAIGVSNF L D+L + VTP VNQVE HP+ Sbjct: 122 DILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPL 181 Query: 183 WQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWG 242 Q L C +K + + +SPLG K+L NPI++ + K KT AQV LRW Sbjct: 182 NNQADLRAFCDAKQIKVEAWSPLGQG-------KLLSNPILSAIGAKYNKTAAQVILRWN 234 Query: 243 LQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFT 276 +Q +PKS R++EN D+FD+ + ED+ + Sbjct: 235 IQKNLITIPKSVHRERIEENADIFDFELGAEDVMS 269 >1QWK-A nrPDB Length = 317 Score = 193 bits (491), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 111/295 (37%), Positives = 173/295 (58%), Gaps = 23/295 (7%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 56 M++ +L+ G ++P +GLGT+ A V TA++ A+K GYR ID AS+Y NE+ IG Sbjct: 1 MSSATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGT 60 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 +K+L+ +G VKREELFIT+K W+++ P + L ++L+ LQ++YVDLYL H PA+ Sbjct: 61 AIKELLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN 120 Query: 117 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVN- 175 + E + P + W+ +A+Y +G A+A+GVSN+++ +++ L + +TP N Sbjct: 121 DD----MSEHIASP-VEDVWRQFDAVYKAGLAKAVGVSNWNNDQISRALALG-LTPVHNS 174 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKV------------LQNPIV 223 QVE H + Q + CK + ++ Y+ LGS + L LQ+ V Sbjct: 175 QVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNV 234 Query: 224 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF 278 +AEK KT AQV LR+ L G ++LPKS R+KEN +VFD+S+ E+ K Sbjct: 235 LALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKL 289 >1FRB-A nrPDB Length = 315 Score = 193 bits (490), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 117/281 (41%), Positives = 175/281 (62%), Gaps = 14/281 (4%) Query: 7 FFELNTGAKLPCVGLGTYA----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA Y NE E+G +++ I Sbjct: 3 FVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKI 62 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 121 + V+RE+LFI SKLW + + +A +KTL DL++DY+DLYLIHWP L+ + L Sbjct: 63 KEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELF 122 Query: 122 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P + + +K W+ ME L D G +A+GVSNF+ ++ LLN + P N Sbjct: 123 PKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTN 182 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 232 QVECHP Q+ L + C SKG+ ++ YSPLGS + + + +L++P + E+A K K Sbjct: 183 QVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEK 242 Query: 233 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPED 273 T+AQV +R+ +Q V+PKS + +R++EN+ VFD+ + ++ Sbjct: 243 TSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDE 283 >1AFS-A nrPDB Length = 323 Score = 192 bits (489), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 117/284 (41%), Positives = 164/284 (57%), Gaps = 19/284 (6%) Query: 10 LNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 LN G +P +G GT V A + AI G+RH D A +Y E+E+G ++ I Sbjct: 10 LNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKI 69 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 121 DG VKRE++F TSKLWS H PE V LEKTL+ Q+DYVDLY+IH+P +L+ + Sbjct: 70 EDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIFF 129 Query: 122 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P E + DI TW+AME D+G A++IGVSNF+ ++L +LN + P N Sbjct: 130 PRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCN 189 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLG-SQSKGEVRLK---VLQNPIVTEVAEKLG 231 QVECH Q + + CKSK + L Y LG S+ K V K +L +P++ +A+K Sbjct: 190 QVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCAIAKKYK 249 Query: 232 KTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIP-EDL 274 +T A VALR+ LQ G L +S + R+KE VF++ + ED+ Sbjct: 250 QTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDM 293 >4MHB-A nrPDB Length = 297 Score = 191 bits (486), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 106/273 (38%), Positives = 149/273 (54%), Gaps = 31/273 (11%) Query: 9 ELNTGAKLPCVGLGTYAMVATA-----IEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIG 63 +LN G +P +G G + M TA + AI+ GYR ID A+ Y NE ++G LK L G Sbjct: 19 KLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNALK-LSG 77 Query: 64 DGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPT 123 + R+ELFIT+KLW D E E++L LQ+DYVDLYLIH P Sbjct: 78 ---IARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPYG--------- 125 Query: 124 PEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVW 183 D+ W+AME L+ +GK RAIGVSNF +L DL+ ++ PAVNQ+E +P Sbjct: 126 -------DVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFNKIIPAVNQIEVNPFN 178 Query: 184 QQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGL 243 QQ +S+G+ ++P G + QNP++T + EK GK+ QV LRW Sbjct: 179 QQLHAVPWMQSRGIQPEAWAPFAEGRNG-----LFQNPVLTAIGEKYGKSVGQVVLRWIF 233 Query: 244 QTGHSVLPKSSSGARLKENLDVFDWSI-PEDLF 275 Q G L KS R++EN+++ D+ + ED+ Sbjct: 234 QRGIVSLAKSVRKGRMEENINILDFELSAEDML 266 >3O3R-A nrPDB Length = 316 Score = 191 bits (485), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 119/281 (42%), Positives = 172/281 (61%), Gaps = 14/281 (4%) Query: 7 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 F +L T AK+P VGLGT+ V A++ AI GYRH DCA +Y NE E+G +++ I Sbjct: 4 FVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKI 63 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK--KESL 120 + V+RE+LFI SKLWS + +A +KTL DL++DY+DLYLIHWP L+ KE L Sbjct: 64 KEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGKEFL 123 Query: 121 MPTPE---MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 + +++K W+ ME L D G +A+GVSNF+ ++ LLN + P N Sbjct: 124 PKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTN 183 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 232 QVECHP Q+ L + C SKG+ + YSPLGS + + + VL+ P + E+A K K Sbjct: 184 QVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAKHKK 243 Query: 233 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPED 273 T AQV +R+ +Q +V+PKS + + +KEN+ VFD+ + E+ Sbjct: 244 TIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEE 284 >1C9W-A nrPDB Length = 315 Score = 191 bits (484), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 118/278 (42%), Positives = 172/278 (61%), Gaps = 14/278 (5%) Query: 7 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA Y NE E+G +++ I Sbjct: 3 FVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKI 62 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 121 + V+RE+LFI SKLW + + +A +KTL DL++DY+DLYLIHWP L+ + L Sbjct: 63 KEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELF 122 Query: 122 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P + + +K W+ ME L D G +A+GVSNF+ ++ +LN + P N Sbjct: 123 PKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTN 182 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 232 QVECHP Q+ L E C SKG+ ++ YSPLGS ++ + + +L++P + E+A K K Sbjct: 183 QVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHKK 242 Query: 233 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 T+AQV +R+ +Q V+PKS + AR+ EN VFD+ + Sbjct: 243 TSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQL 280 >5UXF-A nrPDB Length = 342 Score = 189 bits (479), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 115/317 (36%), Positives = 175/317 (55%), Gaps = 25/317 (7%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY-------AMVATAIEQAIKIGYRHIDCASIYGNEKE 53 M++ +LN G +P +G GTY + A A+ +GYRH+D A Y E+E Sbjct: 20 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEE 79 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 IG ++ I G VKRE+LF+T+KLW PE V ALEK+L+ LQ+DYVDLY++H+P Sbjct: 80 IGQAIQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPV 139 Query: 114 SLKK-ESLMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 +K ++ P E +L D TW+ +E D+G ++IGVSNF+ ++L +LN Sbjct: 140 PMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKP 199 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK----VLQNPI 222 + P NQVECH Q+ L + C+SK + L Y LG+Q E + +L +P+ Sbjct: 200 GLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPV 259 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFT----- 276 + +VA+K ++ A +ALR+ +Q G L +S ++ENL VF + + PED+ T Sbjct: 260 LCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLN 319 Query: 277 -KFSNIPQEKFCRATEF 292 F +P E E+ Sbjct: 320 KNFRYLPAEFLVDHPEY 336 >3KRB-A nrPDB Length = 334 Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 109/302 (36%), Positives = 164/302 (54%), Gaps = 26/302 (8%) Query: 17 PCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGF--VKRE 70 P +G GT+ V TA+E A+ GYRHIDCA +Y NE+ IG K+ D +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 71 ELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKES---LMPTPE-- 125 +++ITSKLW+ +H PE V + +KT+ DLQ+DY+DL+L+HWP + + L P Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 126 --MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVW 183 ML K + TW+AME L + G + IGVSN++ L DLLN A++ P VNQ+E HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWH 205 Query: 184 QQQGLHELCKSKGVHLSGYSPLGS------QSKGEVRLKVLQNPIVTEVAEKLGKTTAQV 237 + C G+ ++ YSP+G G + +L+ + +A+ G + V Sbjct: 206 PNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCV 265 Query: 238 ALRWGLQ----TGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEK---FCRAT 290 AL W ++ + +SV+PKS + AR++ N + + +D +NI K FC Sbjct: 266 ALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIRFCDPA 325 Query: 291 EF 292 F Sbjct: 326 IF 327 >3WCZ-A nrPDB Length = 308 Score = 187 bits (474), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 100/283 (35%), Positives = 166/283 (58%), Gaps = 19/283 (6%) Query: 1 MAAPIRFFELNTGAKLPCVGLGT----------YAMVATAIEQAIKIGYRHIDCASIYGN 50 MA +LN G +P V LGT V A+ AI+ GYRHID A++Y + Sbjct: 1 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 60 Query: 51 EKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIH 110 E+++G + + I +G V REELF+T+KLW++ H + V AL+++L+ L +DY+DLYLIH Sbjct: 61 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 120 Query: 111 WPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARV 170 +P + K + +P+ + D TW+ M+ G AR+IGVSNF++ ++T L++ + + Sbjct: 121 FPIATKPDD---SPDNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 174 Query: 171 TPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLG---SQSKGEVRLKVLQNPIVTEVA 227 P +NQ+E +P Q+ L C+S G+ + YSP G S+ + +P +T +A Sbjct: 175 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 234 Query: 228 EKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 K K+ Q+ LR+ + G +PKS++ R+ +N+D+FD+ + Sbjct: 235 NKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQL 277 >1MZR-A nrPDB Length = 296 Score = 187 bits (474), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 105/282 (37%), Positives = 161/282 (57%), Gaps = 28/282 (9%) Query: 8 FELNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIG 63 +L G +P +GLG + V TAI++A+++GYR ID A+ Y NE+ +G LK Sbjct: 28 IKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALK---- 83 Query: 64 DGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPT 123 + V REELFIT+KLW++DH + +AL +L+ LQ+DY+DLYL+HWP +P Sbjct: 84 NASVNREELFITTKLWNDDH--KRPREALLDSLKKLQLDYIDLYLMHWP--------VPA 133 Query: 124 PEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVW 183 + + WK M L G ++IGV NF L L++ VTP +NQ+E HP+ Sbjct: 134 IDHYVE-----AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLM 188 Query: 184 QQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGL 243 QQ+ LH + + +SPL KG V ++ ++A+K GKT AQ+ +RW L Sbjct: 189 QQRQLHAWNATHKIQTESWSPLAQGGKG-----VFDQKVIRDLADKYGKTPAQIVIRWHL 243 Query: 244 QTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEK 285 +G V+PKS + +R+ EN DV+D+ + +D + + + Q K Sbjct: 244 DSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGK 285 >3D3F-A nrPDB Length = 275 Score = 184 bits (466), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 114/281 (40%), Positives = 162/281 (57%), Gaps = 31/281 (11%) Query: 10 LNTGAKLPCVGLGTYAM-----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64 L+ G ++P GLG + + +++ AIK GYR ID A+IY NE+ +G +K + Sbjct: 10 LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK----E 65 Query: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTP 124 V REELFITSK+W+ D E A EK+L+ LQ+DY+DLYLIHWP Sbjct: 66 SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPG----------- 114 Query: 125 EMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQ 184 K TW+A+E LY GK RAIGVSNF L +LL A + P VNQVE HP Sbjct: 115 ----KDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLT 170 Query: 185 QQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQ 244 Q+ L + CK +G+ L +SPL ++ ++L N ++T++AEK K+ AQV LRW LQ Sbjct: 171 QKELRDYCKGQGIQLEAWSPL-------MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQ 223 Query: 245 TGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEK 285 G +PKS R+ EN D+FD+ + ++ K + +++ Sbjct: 224 HGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDE 264 >4IJC-A nrPDB Length = 344 Score = 167 bits (424), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 104/281 (37%), Positives = 155/281 (55%), Gaps = 30/281 (10%) Query: 7 FFELNTGAKLPCVGLGT------YAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 +F LN G ++P +GLGT A A++ AIK GYRHID A Y E +G +K+ Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK--- 117 L+ DG +KRE+LFIT+K+W L ++V ++L ++L+ L ++YVDL L HWP +K Sbjct: 84 LLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 118 ----ESLMPTP-------EMLTKPDITSTWKAMEALY---DSGKARAIGVSNFSSKKLTD 163 L+ TP D T+K +E +Y + + RAIGVSNFS + L Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 Query: 164 LLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIV 223 L+ RV P VNQVE HP Q L + C + L+ YSPLGS G LK+ P+V Sbjct: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSH--GAPNLKI---PLV 256 Query: 224 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLD 264 ++AEK T + + + ++ G V+P+S + R+ +++ Sbjct: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 >1A80-A nrPDB Length = 277 Score = 166 bits (419), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 99/265 (37%), Positives = 144/265 (54%), Gaps = 26/265 (9%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 LN G +P +G G + A A+E+A+++GYRHID A+IYGNE+ +G + Sbjct: 7 LNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASG--- 63 Query: 66 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPE 125 + R++LFIT+KLW++ H ++ A+ ++L L +D VDLYL+HW PTP Sbjct: 64 -IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHW----------PTP- 111 Query: 126 MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQ 185 + W+ M L +G R+IGVSN L ++ V PAVNQ+E HP +QQ Sbjct: 112 --AADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQ 169 Query: 186 QGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQT 245 + + + + V + + PL G+ + + VT A GKT AQ LRW LQ Sbjct: 170 REITDWAAAHDVKIESWGPL-----GQGKYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQK 224 Query: 246 GHSVLPKSSSGARLKENLDVFDWSI 270 G V PKS RL+ENLDVFD+ + Sbjct: 225 GFVVFPKSVRRERLEENLDVFDFDL 249 >4OTK-A nrPDB Length = 318 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 102/273 (37%), Positives = 141/273 (51%), Gaps = 28/273 (10%) Query: 2 AAPIRFFELNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGV 57 AA LN +P +GLG + A+ A++IG R ID A YGNE +G Sbjct: 43 AAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVG-- 100 Query: 58 LKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK 117 + I V REELF+T+KL + D +A +L L +DYVDLYLIHWPA Sbjct: 101 --RAIAASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPA---- 154 Query: 118 ESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQV 177 P + D W M G AR+IGVSNF+++ + +L+++ VTPAVNQ+ Sbjct: 155 ------PPVGKYVD---AWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTFVTPAVNQI 205 Query: 178 ECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQV 237 E HP+ Q L + V Y PL ++L NP VT +A + KT AQV Sbjct: 206 ELHPLLNQDELRKANAQHTVVTQSYCPLALG-------RLLDNPTVTSIASEYVKTPAQV 258 Query: 238 ALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI 270 LRW LQ G++V+ +S+ R+ N DVFD+ + Sbjct: 259 LLRWNLQLGNAVVVRSARPERIASNFDVFDFEL 291 >3UP8-A nrPDB Length = 298 Score = 162 bits (410), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 89/268 (33%), Positives = 155/268 (57%), Gaps = 30/268 (11%) Query: 11 NTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGF 66 + GA +P +G GT+ M V + QA+K+G+RH+D A IYGNE E+G ++K Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQK----SG 84 Query: 67 VKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEM 126 + R ++F+T+K+W +++ + +++++L+ L+ D+VDL L+HWP S +P E Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWPG-----SDVPMAER 139 Query: 127 LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQQ 186 + A+ + ++GK R IG+SNF++ ++ + ++ A NQVE HP Q Sbjct: 140 I---------GALNEVRNAGKVRHIGISNFNTTQMEEAARLSDAPIATNQVEYHPYLDQT 190 Query: 187 GLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTG 246 + + + G+ L+ Y + + KV +P++TE+ + GKT AQVALRW +Q Sbjct: 191 KVLQTARRLGMSLTSYYAMANG-------KVPADPLLTEIGGRHGKTAAQVALRWLVQQQ 243 Query: 247 HS-VLPKSSSGARLKENLDVFDWSIPED 273 VL K+++ ARLKEN +FD+++ + Sbjct: 244 DVIVLSKTATEARLKENFAIFDFALTRE 271 >3WG6-A nrPDB Length = 307 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 98/317 (30%), Positives = 164/317 (51%), Gaps = 40/317 (12%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA------------MVATAIEQAIKIGYRHIDCASIY 48 M+ + F+L+ G K+P V GT + +E A++ G+RHID A IY Sbjct: 4 MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 63 Query: 49 GNEKEIGGVLKKLIGDGFVKREELFITSKLWSNDHL-------PEDVPKALEKTLQDLQI 101 G KEIG LK + + R+++FIT K S +H ++ AL+ L+DL + Sbjct: 64 GTNKEIGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 119 Query: 102 DYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKL 161 +YVDLYLIH+P +K D+ W+ +E + G AR IGVSNF+ + L Sbjct: 120 EYVDLYLIHFPYISEKSHGF---------DLVEAWRYLERAKNEGLARNIGVSNFTIENL 170 Query: 162 TDLLNVARVT-PAVNQVECHPVWQQQ--GLHELCKSKGVHLSGYSPLGSQSKGEVRLKVL 218 +L+ + P VNQ+E Q Q G+ E + +G+ + Y PLG ++G R L Sbjct: 171 KSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQG--RPGPL 228 Query: 219 QNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF 278 + ++++++EK + Q+ LRW LQ G + +S R+ + L++FD+ + ++ + Sbjct: 229 -DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDEDQI 287 Query: 279 SNIPQEKFCRATEFAHE 295 + + +EK R +F+ E Sbjct: 288 TKVGKEKTLR--QFSKE 302 >4H8N-A nrPDB Length = 310 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 88/270 (32%), Positives = 134/270 (49%), Gaps = 26/270 (9%) Query: 35 IKIGYRHIDCASIYGNEKEIGGVLKKLIGDGFVKREELFITSKL---WSNDHLPEDVPK- 90 +K+G+RHID A Y +KE+G LK+ V RE++++T+K W + P Sbjct: 53 LKLGFRHIDTAEAYNTQKEVGEALKRTD----VPREDIWVTTKYSPGWGSIKAYSKSPSD 108 Query: 91 ALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARA 150 +++K L L +DYVDL+LIH P T E + W+A+ +GK R Sbjct: 109 SIDKALAQLGVDYVDLFLIHSP--------FFTTEQTHGYTLEQAWEALVEAKKAGKVRE 160 Query: 151 IGVSNFSSKKLTDLLNVA---RVTPAVNQVECHPVWQQQ--GLHELCKSKGVHLSGYSPL 205 IG+SN + L L + P VNQ+E HP Q Q + C+ G+ + +SPL Sbjct: 161 IGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPL 220 Query: 206 GSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDV 265 ++ E + +AEK KT AQV LR+ LQ G + SS +RLKE+L++ Sbjct: 221 APLARVETNALA---ETLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNL 277 Query: 266 FDWSIPEDLFTKFSNIPQEKFCRATEFAHE 295 FD+ + ++ + + I RA F HE Sbjct: 278 FDFELTDEEVNEINKIGDANPYRA--FFHE 305 >1PZ1-A nrPDB Length = 333 Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 62/194 (31%), Positives = 96/194 (49%), Gaps = 45/194 (23%) Query: 11 NTGAKLPCVGLGTYAMVAT------------AIEQAIKIGYRHIDCASIYG---NEKEIG 55 +TG + +GLGT+A+ T I A+ G ID A YG +E+ +G Sbjct: 8 DTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVG 67 Query: 56 GVLKKLIGDGFVKREELFITSKL---WSNDHLPEDVPKA-----LEKTLQDLQIDYVDLY 107 +K+ ++KR+++ + +K W N+ L +A +E +L+ LQ DY+DLY Sbjct: 68 KAIKE-----YMKRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLY 122 Query: 108 LIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNV 167 +HWP + L+P I T + M+ LYD+GK RAIGVSNFS +++ V Sbjct: 123 QVHWP-----DPLVP---------IEETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAV 168 Query: 168 A---RVTPAVNQVE 178 A + P N E Sbjct: 169 APLHTIQPPYNLFE 182 >1OG6-A nrPDB Length = 298 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 73/252 (28%), Positives = 100/252 (39%), Gaps = 43/252 (17%) Query: 27 VATAIEQAIKIGYRHIDCASIYGN---EKEIGGVLK------------KLIGDGFVKREE 71 + + IE+ + +G +D A IYG E G LK G REE Sbjct: 34 LVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREE 93 Query: 72 LFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPD 131 I + DH + K+ E++L +L D++DL LIH P L D Sbjct: 94 NVIGHYITDRDH----IIKSAEQSLINLATDHLDLLLIHRPDPLM--------------D 135 Query: 132 ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQ---QGL 188 A + L+ SGK R GVSNF+ + L + T A NQVE PV Q G Sbjct: 136 ADEVADAFKHLHQSGKVRHFGVSNFTPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGT 195 Query: 189 HELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTE---VAEKLGK-TTAQVALRWGLQ 244 + + V +S LG G + P+ E VAE+L + QV W L+ Sbjct: 196 LDQLQQLRVRPMAWSCLGG---GRLFNDDYFQPLRDELAVVAEELNAGSIEQVVNAWVLR 252 Query: 245 TGHSVLPKSSSG 256 LP SG Sbjct: 253 LPSQPLPIIGSG 264 >1PYF-A nrPDB Length = 312 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 43/144 (29%), Positives = 76/144 (52%), Gaps = 31/144 (21%) Query: 31 IEQAIKIGYRHIDCASIYG---NEKEIGGVLKKLIGDGFVKREELFITSKL--------W 79 + +AI+ G +D A IYG +E+ IG VL++ RE++ I +K + Sbjct: 41 VREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF------NREDVVIATKAAHRKQGNDF 94 Query: 80 SNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAM 139 D+ P+ + K+++++L+ L DY+DL+ IH+P + P E + A+ Sbjct: 95 VFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP-----DEHTPKDEAVN---------AL 140 Query: 140 EALYDSGKARAIGVSNFSSKKLTD 163 + +GK R+IGVSNFS ++L + Sbjct: 141 NEMKKAGKIRSIGVSNFSLEQLKE 164 >3N6Q-A nrPDB Length = 346 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 75/332 (22%), Positives = 147/332 (44%), Gaps = 84/332 (25%) Query: 1 MAAPIRFFELN------TGAKLPCVGLGTYAMVA---------TAIEQAIKIGYRHIDCA 45 +A P R+ ++ +G +LP + LG + + +A +G H D A Sbjct: 4 LANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLA 63 Query: 46 SIYG-----NEKEIGGVLKKLIGDGFVKREELFITSK----LWSNDHLPEDVPK----AL 92 + YG E+ G +L++ D R+EL I++K +W + K +L Sbjct: 64 NNYGPPPGSAEENFGRLLRE---DFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL 120 Query: 93 EKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIG 152 +++L+ + ++YVD++ H + + P E T A+ SGKA +G Sbjct: 121 DQSLKRMGLEYVDIFYSH-----RVDENTPMEE---------TASALAHAVQSGKALYVG 166 Query: 153 VSNFS---SKKLTDLLNVARVTPAVNQVECHPV--W-QQQGLHELCKSKGVHLSGYSPL- 205 +S++S ++K+ +LL ++ ++Q + + W + GL + ++ GV ++PL Sbjct: 167 ISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLA 226 Query: 206 ---------------------GSQSKG-------EVRLKVLQNPIVTEVAEKLGKTTAQV 237 G++ +G E L L+ ++ E+A++ G++ AQ+ Sbjct: 227 QGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLR--LLNEMAQQRGQSMAQM 284 Query: 238 ALRWGLQTGH--SVLPKSSSGARLKENLDVFD 267 AL W L+ SVL +S +L+EN+ + Sbjct: 285 ALSWLLKDDRVTSVLIGASRAEQLEENVQALN 316 >3EB3-A nrPDB Length = 327 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 76/308 (24%), Positives = 134/308 (43%), Gaps = 74/308 (24%) Query: 12 TGAKLPCVGLGTYAMVATAI-----EQAIKIGYRH----IDCASIYGNEKE---IGGVLK 59 +G ++ C+GLGT+ I E + + Y + D A +Y K +G ++K Sbjct: 11 SGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIK 70 Query: 60 KLIGDGFVKREELFITSKLWSNDHLPED-------VPKALEKTLQDLQIDYVDLYLIHWP 112 K G+ +R L IT+K+++ + + + L+ +L+ LQ++YVD+ + P Sbjct: 71 K---KGW-RRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 126 Query: 113 ASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVAR--- 169 P M T +AM + + G A G S +SS ++ + +VAR Sbjct: 127 D--------PNTPM------EETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 172 Query: 170 -VTPAVNQVECHPVWQQQ---GLHELCKSKGVHLSGYSPLGS-------------QSKGE 212 + P Q E H +++ L EL GV +SPL S+ Sbjct: 173 LIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRAS 232 Query: 213 VR-LKVLQNPIVTE--------------VAEKLGKTTAQVALRWGLQTG--HSVLPKSSS 255 ++ + L++ I++E +AE+LG T Q+A+ W L+ SVL +S+ Sbjct: 233 LKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASN 292 Query: 256 GARLKENL 263 +L EN+ Sbjct: 293 AEQLMENI 300 >4R9O-A nrPDB Length = 301 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 51/173 (29%), Positives = 74/173 (42%), Gaps = 33/173 (19%) Query: 27 VATAIEQAIKIGYRHIDCASIYGN---EKEIGGVL-------KKL-----IGDGFVKREE 71 + + IE+ + +G +D A IYG E G L +KL G R E Sbjct: 37 LVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTKCGIATTARAE 96 Query: 72 LFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPD 131 + + H + + E++L++L DY+D+ LIH P L D Sbjct: 97 NKLGHYITDRRH----IILSAEQSLKNLATDYLDMLLIHRPDPLM--------------D 138 Query: 132 ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQ 184 +A + L+ SGK R GVSNF+ + T L + T A NQVE PV Q Sbjct: 139 ADDVAEAFQHLHQSGKVRHFGVSNFTPAQFTLLQSRLPFTLATNQVEISPVHQ 191 >1LQA-A nrPDB Length = 346 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 80/334 (23%), Positives = 136/334 (40%), Gaps = 71/334 (21%) Query: 15 KLPCVGLGTY--------AMVATAIEQAIKIGYRHIDCASIYG--NEKEIGGVLKKLIGD 64 ++ +GLGT A ++ A+ G ID A +Y E G+ + +G+ Sbjct: 12 EVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGN 71 Query: 65 GFVK---REELFITSKL----WSNDH--LPE------DVPKALEKTLQDLQIDYVDLYLI 109 K RE+L I SK+ +ND P+ ++ +AL +L+ LQ DY+DLY + Sbjct: 72 WLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQV 131 Query: 110 HWP-------ASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLT 162 HWP L P + + T A+ +GK R IGVSN ++ + Sbjct: 132 HWPQRPTNCFGKLGYSWTDSAPAV----SLLDTLDALAEYQRAGKIRYIGVSNETAFGVM 187 Query: 163 DLLNVA------RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLG---------- 206 L++A R+ N + GL E+ + +GV L YS LG Sbjct: 188 RYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLN 247 Query: 207 ---------------SQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTGH--SV 249 ++ GE K + + ++A + G AQ+AL + + S Sbjct: 248 GAKPAGARNTLFSRFTRYSGEQTQKAVAAYV--DIARRHGLDPAQMALAFVRRQPFVAST 305 Query: 250 LPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQ 283 L +++ +LK N++ + ED+ + + Q Sbjct: 306 LLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQ 339 >1GVE-A nrPDB Length = 327 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 44/187 (23%), Positives = 81/187 (43%), Gaps = 22/187 (11%) Query: 28 ATAIEQAIKIGYRHIDCASIYGN--EKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLP 85 + ++ ++ G+ ID A +Y N + I G L +G K + + ++ P Sbjct: 25 SASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATKAAPMFGKTLKP 84 Query: 86 EDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDS 145 DV LE +L+ LQ VDL+ +H+P TP I T +A L+ Sbjct: 85 ADVRFQLETSLKRLQCPRVDLFYLHFPDH-------GTP-------IEETLQACHQLHQE 130 Query: 146 GKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHELCKSKGVHL 199 GK +G+SN+ S ++ ++ + + + P V Q + + +Q L + G+ Sbjct: 131 GKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRF 190 Query: 200 SGYSPLG 206 ++PL Sbjct: 191 YAFNPLA 197 >2CLP-A nrPDB Length = 347 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 20/135 (14%) Query: 78 LWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWK 137 L+ N P+ + LE +L+ LQ VDL+ +H P TP + T + Sbjct: 97 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDH-------STP-------VEETLR 142 Query: 138 AMEALYDSGKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHEL 191 A L+ GK +G+SN+++ ++ ++ + + + P V Q + + +Q L Sbjct: 143 ACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPC 202 Query: 192 CKSKGVHLSGYSPLG 206 + G+ ++PL Sbjct: 203 LRHFGLRFYAFNPLA 217 >2BP1-A nrPDB Length = 360 Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust. Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 21/145 (14%) Query: 69 REELFITSKLWSNDHL-PEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEML 127 R ++ + W L P+ V LE +L+ LQ VDL+ +H P TP Sbjct: 100 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDH-------GTP--- 149 Query: 128 TKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVW 183 + T A + L+ GK +G+SN++S ++ ++ + + + P V Q + Sbjct: 150 ----VEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 205 Query: 184 QQ--QGLHELCKSKGVHLSGYSPLG 206 +Q L + G+ Y+PL Sbjct: 206 RQVETELFPCLRHFGLRFYAYNPLA 230 >2C91-A nrPDB Length = 338 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 20/128 (15%) Query: 85 PEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYD 144 P+ + LE +L+ LQ VDL+ +H P + P E L A L+ Sbjct: 95 PDSIRSQLETSLKRLQCPRVDLFYLHAP-----DHSTPVEETLC---------ACHQLHQ 140 Query: 145 SGKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHELCKSKGVH 198 GK +G+SN++S ++ ++ + + + P V Q + +Q L + G+ Sbjct: 141 EGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLRHFGLR 200 Query: 199 LSGYSPLG 206 Y+PL Sbjct: 201 FYAYNPLA 208 >6NBX-H nrPDB Length = 394 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 7/60 (11%) Query: 217 VLQNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLK-----ENLDVFDWSIP 271 + NPI + +GK + + A+ WGL +L S L+ E D FDW +P Sbjct: 194 ITNNPIFVRRLQGVGKISREEAINWGLSG--PMLRASGVKWDLRKVDHYECYDDFDWDVP 251 >3B0X-A nrPDB Length = 575 Score = 27.7 bits (60), Expect = 6.2, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 12/84 (14%) Query: 210 KGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWS 269 +G VRL P V EV K GK A V L+ GLQ V+P S GA L+ S Sbjct: 213 EGFVRL-----PQVKEVYAK-GKERATVFLKNGLQVDLRVVPPESYGAGLQYLTGSAAHS 266 Query: 270 IPEDLFTKFSNIPQEKFCRATEFA 293 I + + QEK + +E+ Sbjct: 267 I------RLRALAQEKGLKLSEYG 284 >2NZ0-B nrPDB Length = 140 Score = 27.7 bits (60), Expect = 7.4, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 36 KIGYRHIDCASIYGNEKEIGGVLKKLIGD 64 K+ Y +C S Y +E G+L ++IGD Sbjct: 97 KLHYPRYECISAYDDELAFYGILPEIIGD 125 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3H7R-A nrPDB 484 e-137 3H7U-A nrPDB 462 e-131 5JH1-A nrPDB 437 e-123 1ZUA-X nrPDB 413 e-116 4JQA-A nrPDB 404 e-113 1Q5M-A nrPDB 403 e-113 5JM5-A nrPDB 400 e-112 2FVL-A nrPDB 395 e-110 2ALR-A nrPDB 388 e-108 2BGQ-A nrPDB 387 e-108 3RX4-A nrPDB 387 e-108 5UXF-A nrPDB 386 e-108 3G1R-A nrPDB 385 e-107 1HQT-A nrPDB 385 e-107 4GAC-A nrPDB 383 e-107 1DLA-A nrPDB 381 e-106 4HBK-A nrPDB 380 e-106 2HE8-A nrPDB 380 e-106 1AFS-A nrPDB 378 e-105 1C9W-A nrPDB 371 e-103 1FRB-A nrPDB 371 e-103 5Z6T-A nrPDB 362 e-100 4GIE-A nrPDB 360 e-100 5ZCM-A nrPDB 360 e-100 3O3R-A nrPDB 358 1e-99 3WCZ-A nrPDB 358 2e-99 1K8C-A nrPDB 357 3e-99 1VBJ-A nrPDB 346 5e-96 1VP5-A nrPDB 344 3e-95 4F40-A nrPDB 341 3e-94 3KRB-A nrPDB 337 5e-93 1QWK-A nrPDB 335 2e-92 1MZR-A nrPDB 333 5e-92 4MHB-A nrPDB 326 1e-89 3D3F-A nrPDB 319 9e-88 4OTK-A nrPDB 308 2e-84 4IJC-A nrPDB 304 4e-83 1A80-A nrPDB 296 6e-81 3WG6-A nrPDB 289 8e-79 3UP8-A nrPDB 288 2e-78 4H8N-A nrPDB 273 8e-74 1LQA-A nrPDB 202 1e-52 3EB3-A nrPDB 191 3e-49 3N6Q-A nrPDB 185 2e-47 1OG6-A nrPDB 176 1e-44 4R9O-A nrPDB 170 7e-43 1PZ1-A nrPDB 168 2e-42 1PYF-A nrPDB 166 1e-41 1GVE-A nrPDB 148 3e-36 Sequences not found previously or not previously below threshold: 2CLP-A nrPDB 136 1e-32 2C91-A nrPDB 126 1e-29 2BP1-A nrPDB 126 2e-29 4EXA-A nrPDB 64 8e-11 1TMO-A nrPDB 32 0.40 1BE1-A nrPDB 31 0.68 5GZ9-A nrPDB 31 0.82 4EHI-A nrPDB 31 0.96 3Q3N-A nrPDB 29 2.4 5AZD-A nrPDB 29 2.6 2P1I-A nrPDB 29 2.8 2WUA-A nrPDB 29 2.9 6O81-C nrPDB 29 3.2 4FO0-A nrPDB 29 3.2 2AXQ-A nrPDB 28 3.9 5EY9-A nrPDB 28 3.9 4YWJ-A nrPDB 28 4.5 1JPH-A nrPDB 28 5.0 2B0D-A nrPDB 28 8.0 2GE5-A nrPDB 28 8.1 >3H7R-A nrPDB Length = 331 Score = 484 bits (1245), Expect = e-137, Method: Composition-based stats. Identities = 311/311 (100%), Positives = 311/311 (100%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK Sbjct: 21 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 80 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 120 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL Sbjct: 81 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 140 Query: 121 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH 180 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH Sbjct: 141 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH 200 Query: 181 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR 240 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR Sbjct: 201 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR 260 Query: 241 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY 300 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY Sbjct: 261 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY 320 Query: 301 KTIEELWDGEI 311 KTIEELWDGEI Sbjct: 321 KTIEELWDGEI 331 >3H7U-A nrPDB Length = 335 Score = 462 bits (1190), Expect = e-131, Method: Composition-based stats. Identities = 211/315 (66%), Positives = 243/315 (77%), Gaps = 4/315 (1%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 56 MA I FF+LNTGAK P VGLGT+ +V A+ A+KIGYRHIDCA IYGNEKEIG Sbjct: 21 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 80 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 VLKKL D VKRE+LFITSKLW DH P+DVP+AL +TL+DLQ++YVDLYLIHWPA +K Sbjct: 81 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 140 Query: 117 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQ 176 K S+ PE L DI STWKAMEALYDSGKARAIGVSNFS+KKL DLL +ARV PAVNQ Sbjct: 141 KGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQ 200 Query: 177 VECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQ 236 VECHP W+Q L E CKSKGVHLS YSPLGS ++ VL+NPI+ VAEKLGK+ AQ Sbjct: 201 VECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQ 260 Query: 237 VALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHET 296 VALRWGLQ GHSVLPKS++ R+KEN +VFDWSIP+ +F KF+ I Q + + HET Sbjct: 261 VALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHET 320 Query: 297 HGFYKTIEELWDGEI 311 YK+IEELWDGEI Sbjct: 321 LSPYKSIEELWDGEI 335 >5JH1-A nrPDB Length = 309 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 190/311 (61%), Positives = 229/311 (73%), Gaps = 6/311 (1%) Query: 5 IRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 R F LNTGAK+P VGLG++ +V A+ A+K GYRHIDCA +YGNEKEIG LKK Sbjct: 1 ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 120 L +G VKRE++FITSKLW++ H PEDVP+AL +L DLQ++Y+DLYLIHWP +KK + Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGTN 120 Query: 121 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH 180 +PE PD +TW AME LYD+GKARAIGVSNFSSKKL DLL VARV PAV+QVECH Sbjct: 121 T-SPENFVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVARVPPAVDQVECH 179 Query: 181 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR 240 P WQQ LH C+S GVHL+ YSPLGS + VL+ PI+ +AEKLGKT+AQVALR Sbjct: 180 PGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGNVLKEPIIISIAEKLGKTSAQVALR 239 Query: 241 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFY 300 W +Q GHSVLPKS++ R+K+NLDV+DWSIP+DL KFS I Q + R F Y Sbjct: 240 WNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEIKQARLLRGN-FIVNPESVY 298 Query: 301 KTIEELWDGEI 311 KT EELWDGE+ Sbjct: 299 KTHEELWDGEL 309 >1ZUA-X nrPDB Length = 317 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 127/311 (40%), Positives = 181/311 (58%), Gaps = 16/311 (5%) Query: 5 IRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA +Y NE E+G +++ Sbjct: 3 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 62 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ES 119 I + VKRE+LFI SKLW V KA EKTL+DL++ Y+D+YLIHWP K + Sbjct: 63 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 122 Query: 120 LMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPA 173 L P + + K W+AME L D G +A+GVSNFS ++ LLN + P Sbjct: 123 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 182 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKL 230 NQVECHP Q+ L + C SKG+ ++ YSPLGS + + + +L++P + E+A K Sbjct: 183 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 242 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF-SNIPQEKFCRA 289 KT AQV +R+ +Q V+PKS + AR+ EN+ VFD+ + ++ S + C Sbjct: 243 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 302 Query: 290 TEFAH-ETHGF 299 + +H E + F Sbjct: 303 LQSSHLEDYPF 313 >4JQA-A nrPDB Length = 331 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 121/319 (37%), Positives = 187/319 (58%), Gaps = 19/319 (5%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKE 53 M + + +LN G +P +G GTYA A++ AI+ G+ HID A +Y NE++ Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 +G ++ I DG VKRE++F TSKLWSN H PE V ALE++L++LQ+DYVDLYLIH+P Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 114 SLKKESLM-PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 S+K + P E + D+ +TW+AME D+G A++IGVSNF+ + L +LN Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSK----GEVRLKVLQNPI 222 + P NQVECHP + Q+ L + CKSK + L YS LGS + +L++P+ Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 + +A+K +T A +ALR+ LQ G VL KS + R+++N+ VF++ + + + Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300 Query: 283 QE-KFCRATEFAHETHGFY 300 + ++ FA + + Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319 >1Q5M-A nrPDB Length = 322 Score = 403 bits (1036), Expect = e-113, Method: Composition-based stats. Identities = 128/312 (41%), Positives = 183/312 (58%), Gaps = 20/312 (6%) Query: 8 FELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 L+ G +P +G GTYA A + AI G+RHID A Y NEKE+G ++ Sbjct: 7 VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRS 66 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-S 119 I DG VKRE++F TSKLW H PE V +LE +L++LQ+DYVDLY+IH+P +LK Sbjct: 67 KIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVE 126 Query: 120 LMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPA 173 ++PT E + DI +TW+AME D+G A++IGVSNF+ ++L +LN + P Sbjct: 127 IIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 186 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEV----RLKVLQNPIVTEVAEK 229 NQVECHP Q L E CKSKG+ L YS LGS + E +L++P++ +A+K Sbjct: 187 CNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKK 246 Query: 230 LGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRA 289 +T A +ALR+ LQ G VL KS + R+KEN+ VF++ +P + ++ + Sbjct: 247 HQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYVT 306 Query: 290 TEFA--HETHGF 299 +FA H + F Sbjct: 307 ADFAIGHPNYPF 318 >5JM5-A nrPDB Length = 332 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 124/319 (38%), Positives = 183/319 (57%), Gaps = 19/319 (5%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKE 53 M + + +LN G +P +G GTYA + AI+ G+RHID A +Y NE++ Sbjct: 1 MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 +G ++ I DG VKRE++F TSKLWS H PE V ALE +L+ Q+DYVDLYLIH P Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 114 SLKK-ESLMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 SLK E L PT E + D+ +TW+AME D+G A++IGVSNF+ ++L +LN Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSK----GEVRLKVLQNPI 222 + P NQVECHP + + L + CKSK + L YS LGSQ +L++P+ Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 + +A+K +T A +ALR+ LQ G VL KS + R+++N+ VF++ + + + Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300 Query: 283 QE-KFCRATEFAHETHGFY 300 + + + FA + Y Sbjct: 301 RNLHYFNSDSFASHPNYPY 319 >2FVL-A nrPDB Length = 324 Score = 395 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 117/319 (36%), Positives = 178/319 (55%), Gaps = 20/319 (6%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKE 53 M + ELN G +P +G GTYA + AI+ G+RHID A +Y NE++ Sbjct: 2 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 61 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 +G ++ I DG VKRE++F TSKLW P+ V ALE +L+ LQ+DYVDLYL+H+P Sbjct: 62 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 121 Query: 114 SLKKESL-MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 +LK +P E + D+++TW+ ME D+G A++IGVSNF+ ++L +LN Sbjct: 122 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKP 181 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSK----GEVRLKVLQNPI 222 + P NQVECHP Q L + CKSK + L +S LG+Q +L++P+ Sbjct: 182 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 241 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 + +A+K +T A +ALR+ LQ G VL KS + R++EN+ VF++ + + + Sbjct: 242 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 301 Query: 283 QEKFCRATEFA--HETHGF 299 + +F H + F Sbjct: 302 RNYRYVVMDFLMDHPDYPF 320 >2ALR-A nrPDB Length = 324 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 124/294 (42%), Positives = 182/294 (61%), Gaps = 13/294 (4%) Query: 4 PIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLK 59 L+TG K+P +GLGT+ V A++ A+ +GYRHIDCA+IYGNE EIG LK Sbjct: 1 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 60 Query: 60 KLIGDG-FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE 118 + +G G V REELF+TSKLW+ H PEDV AL KTL DLQ++Y+DLYL+HWP + ++ Sbjct: 61 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120 Query: 119 SL-MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPA 173 P TWKA+EAL G +A+G+SNF+S+++ D+L+VA V PA Sbjct: 121 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 180 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKL 230 V QVECHP Q L C+++G+ ++ YSPLGS + +L+ P+V +AEK Sbjct: 181 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKY 240 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQE 284 G++ AQ+ LRW +Q +PKS + +R+ +N+ VFD++ + + + + + Sbjct: 241 GRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKN 294 >2BGQ-A nrPDB Length = 344 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 136/311 (43%), Positives = 188/311 (60%), Gaps = 13/311 (4%) Query: 7 FFELNTGAKLPCVGLGTYA---MVATAIEQAI-KIGYRHIDCASIYGNEKEIGGVLKKLI 62 F L +G +P VGLGT+ A ++ AI + GYRH+D A+ YG EKE+G LK + Sbjct: 39 HFVLKSGHAMPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAM 98 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMP 122 + + R++LF+TSK+W + PE V ALE TL+DLQ+DY+DLY IHWP LK + MP Sbjct: 99 -EAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMP 157 Query: 123 TPEM-LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHP 181 + + D+ WK ME L G + IGV N++ KL LL A++ PAV Q+E HP Sbjct: 158 PEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHP 217 Query: 182 VWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRW 241 W+ + E CK G+H++ YSPLGS K + +P+V +VA KL KT QV ++W Sbjct: 218 GWKNDKIFEACKKHGIHITAYSPLGSSEK-----NLAHDPVVEKVANKLNKTPGQVLIKW 272 Query: 242 GLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATE--FAHETHGF 299 LQ G SV+PKSS R+KEN+ VF W IPE+ F +I EK E F ++THG Sbjct: 273 ALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFVNKTHGP 332 Query: 300 YKTIEELWDGE 310 Y++ ++WD E Sbjct: 333 YRSARDVWDHE 343 >3RX4-A nrPDB Length = 336 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 126/308 (40%), Positives = 184/308 (59%), Gaps = 16/308 (5%) Query: 10 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 65 LN GAK+P +GLGT+ V A++ AI +GYRHIDCA +Y NE E+G +++ + + Sbjct: 27 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 86 Query: 66 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-SLMPTP 124 VKREELFI SKLW H V A +KTL DL++DY+DLYLIHWP K P Sbjct: 87 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 146 Query: 125 E----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVNQVE 178 E + + +I TW AME L D G +AIG+SNF+ ++ +LN + PAVNQ+E Sbjct: 147 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 206 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGKTTA 235 CHP Q+ L + C+SKG+ ++ YSPLGS + + + +L++P + +A K KTTA Sbjct: 207 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 266 Query: 236 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFTKFSNIPQEKFCRATEF-A 293 QV +R+ +Q V+PKS + R+ EN VFD+ + +D+ T S + C + Sbjct: 267 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTS 326 Query: 294 HETHGFYK 301 H+ + F++ Sbjct: 327 HKDYPFHE 334 >5UXF-A nrPDB Length = 342 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 113/323 (34%), Positives = 170/323 (52%), Gaps = 19/323 (5%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKE 53 M++ +LN G +P +G GTY A A+ +GYRH+D A Y E+E Sbjct: 20 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEE 79 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 IG ++ I G VKRE+LF+T+KLW PE V ALEK+L+ LQ+DYVDLY++H+P Sbjct: 80 IGQAIQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPV 139 Query: 114 SLKKESL-MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 +K P E +L D TW+ +E D+G ++IGVSNF+ ++L +LN Sbjct: 140 PMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKP 199 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEV----RLKVLQNPI 222 + P NQVECH Q+ L + C+SK + L Y LG+Q E +L +P+ Sbjct: 200 GLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPV 259 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 + +VA+K ++ A +ALR+ +Q G L +S ++ENL VF + + + + Sbjct: 260 LCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLN 319 Query: 283 QEKFCRATEFAHETHGFYKTIEE 305 + EF H Y +EE Sbjct: 320 KNFRYLPAEFLV-DHPEYPFVEE 341 >3G1R-A nrPDB Length = 346 Score = 385 bits (989), Expect = e-107, Method: Composition-based stats. Identities = 114/325 (35%), Positives = 184/325 (56%), Gaps = 22/325 (6%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY--------AMVATAIEQAIKIGYRHIDCASIYGNEK 52 ++A L+ G +P +GLGTY AT+++ AI GYRHID A IY NE Sbjct: 23 LSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEH 82 Query: 53 EIGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWP 112 E+G +++ I +G V+RE++F KLW+ +H+PE V LE+TL+ LQ+DYVDLY+I P Sbjct: 83 EVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVP 142 Query: 113 ASLKK-ESLMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNV 167 + K + + P E + K ++ +TW+AMEA D+G +++GVSNF+ ++L +LN Sbjct: 143 MAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK 202 Query: 168 A--RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEV----RLKVLQNP 221 + P NQVECHP + Q L + C+ + ++ YSPLG+ +L++ Sbjct: 203 PGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDA 262 Query: 222 IVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNI 281 ++ + ++ KT AQ+ LR+ +Q G V+PKS + R+KEN +FD+S+ E+ + Sbjct: 263 LLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEAL 322 Query: 282 PQE-KFCRATEFAHETHGFYKTIEE 305 + +F + H Y +E Sbjct: 323 NKNVRFVELLMW--RDHPEYPFHDE 345 >1HQT-A nrPDB Length = 326 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 125/295 (42%), Positives = 182/295 (61%), Gaps = 15/295 (5%) Query: 4 PIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLK 59 L+TG K+P +GLGT+ V AI+ A+ +GYRHIDCA+I+GNE EIG L+ Sbjct: 3 AASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQ 62 Query: 60 KLIGDG-FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE 118 + +G G V REELF+TSKLW+ H PEDV AL KTL DLQ++Y+DLYL+HWP + ++ Sbjct: 63 ETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 122 Query: 119 SLMPTPEM------LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTP 172 P P+ TWKA+EAL G RA+G+SNFSS+++ D+L+VA V P Sbjct: 123 DN-PFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRP 181 Query: 173 AVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGE---VRLKVLQNPIVTEVAEK 229 AV QVECHP Q L C+++G+ ++ YSPLGS + +L+ P+V +AEK Sbjct: 182 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEK 241 Query: 230 LGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQE 284 ++ AQ+ LRW +Q +PKS + +R+ +N+ VFD++ + + + + Sbjct: 242 YNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKN 296 >4GAC-A nrPDB Length = 324 Score = 383 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 125/294 (42%), Positives = 180/294 (61%), Gaps = 15/294 (5%) Query: 5 IRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 L+TG K+P +GLGT+ V AI+ A+ GYRHIDCAS+YGNE EIG LK+ Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 61 LIGDG-FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKES 119 +G G V REELF+TSKLW+ H PEDV AL KTL DLQ++Y+DLYL+HWP + ++ Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 120 LMPTPEM------LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPA 173 P P+ TWKA+E L G +A+G+SNF+S+++ D+L+VA V PA Sbjct: 122 N-PFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPA 180 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKL 230 V QVECHP Q L C ++G+ ++ YSPLGS + +L+ P+V +AEK Sbjct: 181 VLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKH 240 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQE 284 G++ AQ+ LRW +Q +PKS + +R+ +N+ VFD++ + + + + Sbjct: 241 GRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKN 294 >1DLA-A nrPDB Length = 314 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 129/311 (41%), Positives = 183/311 (58%), Gaps = 16/311 (5%) Query: 7 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 L TGAK+P +GLGT+ V A++ AI +GYRHIDCA +Y NE E+G L++ + Sbjct: 2 HLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKL 61 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-SLM 121 VKRE+LFI SKLW DH V A + TL+DL++DY+DLYLIHWP K Sbjct: 62 QGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPF 121 Query: 122 PTP----EMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P + + D TW+AME L D G +AIGVSNF+ ++ +LN + PAVN Sbjct: 122 PLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVN 181 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 232 Q+E HP Q+ L E CKSKG+ ++ YSPLGS + + + +L++P + +A K K Sbjct: 182 QIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNK 241 Query: 233 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFTKFSNIPQEKFCRATE 291 TTAQV +R+ +Q V+PKS + R+ EN VFD+ + PED+ T S + C Sbjct: 242 TTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMS 301 Query: 292 F-AHETHGFYK 301 +H+ + F++ Sbjct: 302 CASHKDYPFHE 312 >4HBK-A nrPDB Length = 344 Score = 380 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 115/305 (37%), Positives = 180/305 (59%), Gaps = 11/305 (3%) Query: 8 FELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIG 63 ++N G +P +GLGT+ V A+++A++IGYRH+DCA +Y NE EIG L+ + Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 64 DGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-SLMP 122 +KRE++FITSKLW+ PE V KA E+TL++L+++Y+DLYLIHWP LK L P Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 123 TPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVE 178 T L TWK ME L D G ++IG+SNF+ +++ ++L R+ PA Q+E Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEHCRIKPANLQIE 217 Query: 179 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVA 238 H + L E +S G+ ++ Y+PLGS + ++ +L P V E+A + KT AQV Sbjct: 218 IHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHSPGKVNLLTKPCVLEIAHRHKKTPAQVL 277 Query: 239 LRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFS--NIPQEKFCRATEFAHET 296 LR+ LQ V+PKS + R++EN VFD+ + + + + ++ + +F H+ Sbjct: 278 LRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELNTESLNERQFTLLQMSGHQE 337 Query: 297 HGFYK 301 + F + Sbjct: 338 YPFKE 342 >2HE8-A nrPDB Length = 323 Score = 380 bits (976), Expect = e-106, Method: Composition-based stats. Identities = 111/312 (35%), Positives = 163/312 (52%), Gaps = 18/312 (5%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY-------AMVATAIEQAIKIGYRHIDCASIYGNEKE 53 M + LN G +P +G GT + + AI G+ H D AS+Y E Sbjct: 1 MNSKCHCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDH 60 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 +G ++ I DG V+RE++F TSK+W PE V +LE++LQ LQ DYVDLYLIH+P Sbjct: 61 VGEAIRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPM 120 Query: 114 SLKK-ESLMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 +LK E P E + + D+ +TW+AME D+G ++IGVSNF+ ++L +LN Sbjct: 121 ALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKP 180 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKG----EVRLKVLQNPI 222 + P NQVECHP Q L + CKSK + L Y LG+Q G + +L P+ Sbjct: 181 GLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPV 240 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 + +A+K +T A +ALR+ LQ G VL S R+KEN+ VF++ + + + Sbjct: 241 LGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLN 300 Query: 283 QEKFCRATEFAH 294 + Sbjct: 301 RNMRYIPAAIFK 312 >1AFS-A nrPDB Length = 323 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 116/319 (36%), Positives = 165/319 (51%), Gaps = 20/319 (6%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA-------MVATAIEQAIKIGYRHIDCASIYGNEKE 53 M + LN G +P +G GT V A + AI G+RH D A +Y E+E Sbjct: 1 MDSISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEE 60 Query: 54 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 113 +G ++ I DG VKRE++F TSKLWS H PE V LEKTL+ Q+DYVDLY+IH+P Sbjct: 61 VGQAIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPM 120 Query: 114 SLKKES-LMPTPEM----LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA 168 +L+ P E DI TW+AME D+G A++IGVSNF+ ++L +LN Sbjct: 121 ALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKP 180 Query: 169 --RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEV----RLKVLQNPI 222 + P NQVECH Q + + CKSK + L Y LGS +L +P+ Sbjct: 181 GLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPV 240 Query: 223 VTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 + +A+K +T A VALR+ LQ G L +S + R+KE VF++ + + + Sbjct: 241 LCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLN 300 Query: 283 QEKFCRATEFA--HETHGF 299 + ++ H H F Sbjct: 301 RNFRYNNAKYFDDHPNHPF 319 >1C9W-A nrPDB Length = 315 Score = 371 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 122/311 (39%), Positives = 180/311 (57%), Gaps = 15/311 (4%) Query: 7 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA Y NE E+G +++ I Sbjct: 3 FVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKI 62 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-SLM 121 + V+RE+LFI SKLW + + +A +KTL DL++DY+DLYLIHWP L+ L Sbjct: 63 KEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELF 122 Query: 122 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 175 P + + +K W+ ME L D G +A+GVSNF+ ++ +LN + P N Sbjct: 123 PKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTN 182 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 232 QVECHP Q+ L E C SKG+ ++ YSPLGS ++ + + +L++P + E+A K K Sbjct: 183 QVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHKK 242 Query: 233 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPE-DLFTKFSNIPQEKFCRATE 291 T+AQV +R+ +Q V+PKS + AR+ EN VFD+ + + ++ T + C E Sbjct: 243 TSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACLLPE 302 Query: 292 FAHETHGFYKT 302 + Y Sbjct: 303 TVNMEEYPYDA 313 >1FRB-A nrPDB Length = 315 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 121/313 (38%), Positives = 180/313 (57%), Gaps = 15/313 (4%) Query: 5 IRFFELNTGAKLPCVGLGTYA----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA Y NE E+G +++ Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-S 119 I + V+RE+LFI SKLW + + +A +KTL DL++DY+DLYLIHWP L+ Sbjct: 61 KIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 120 LMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPA 173 L P + + +K W+ ME L D G +A+GVSNF+ ++ LLN + P Sbjct: 121 LFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 180 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKL 230 NQVECHP Q+ L + C SKG+ ++ YSPLGS + + + +L++P + E+A K Sbjct: 181 TNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKH 240 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF-SNIPQEKFCRA 289 KT+AQV +R+ +Q V+PKS + +R++EN+ VFD+ + ++ S + C Sbjct: 241 EKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLL 300 Query: 290 TEFAHETHGFYKT 302 E + Y Sbjct: 301 PETVNMEEYPYDA 313 >5Z6T-A nrPDB Length = 343 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 126/299 (42%), Positives = 170/299 (56%), Gaps = 22/299 (7%) Query: 6 RFFELNTGAKLPCVGLGTYA----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKL 61 +LN+G +P VG G + + I +AIK GYR D A Y NEK +G +KK Sbjct: 27 PSIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKA 86 Query: 62 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK---E 118 I +G VKRE+LF+TSKLW+N H P++V KAL +TL DLQ+DYVDL+LIH+P + K E Sbjct: 87 IDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLE 146 Query: 119 SLMPTPEMLTKPD--------ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARV 170 P K D I TWKA+E L +GK R+IGVSNF L DLL A + Sbjct: 147 EKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATI 206 Query: 171 TPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRL-------KVLQNPIV 223 P+V QVE HP QQ L E +S+G+ ++ YS G QS E+ + +N + Sbjct: 207 KPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETI 266 Query: 224 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 +A K GK+ AQV LRW Q G +++PKS++ RL EN DV + + E F + + Sbjct: 267 KAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLD 325 >4GIE-A nrPDB Length = 290 Score = 360 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 106/292 (36%), Positives = 167/292 (57%), Gaps = 28/292 (9%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY-----AMVATAIEQAIKIGYRHIDCASIYGNEKEIG 55 M L+ ++P +GLG + A A A+ AI+ GYRHID A IY NE+ +G Sbjct: 9 MNCNYNCVTLHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVG 68 Query: 56 GVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASL 115 +++ V REE+++T+K+W++D E A E++ + L ++Y+DLYLIHWP Sbjct: 69 QGIRE----SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPG-- 122 Query: 116 KKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVN 175 K TWKA+E LY+ K RAIGVSNF LT+L ++ P VN Sbjct: 123 -------------KKKFVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFKSCKIRPMVN 169 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTA 235 QVE HP++QQ+ L E CK + ++ +SPLGS + +L+N ++ E+A+K K+ A Sbjct: 170 QVELHPLFQQRTLREFCKQHNIAITAWSPLGSGEEA----GILKNHVLGEIAKKHNKSPA 225 Query: 236 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFC 287 QV +RW +Q G +PKS++ R++EN +V+D+ + E+ + + ++K Sbjct: 226 QVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRI 277 >5ZCM-A nrPDB Length = 341 Score = 360 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 119/300 (39%), Positives = 179/300 (59%), Gaps = 22/300 (7%) Query: 7 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 +LN+G ++P VG G + A A + AIK+GYR D A YGN KEIG + + + Sbjct: 23 SIKLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRAL 82 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK---KES 119 +G V R+ELFITSKLW++ H P++V AL+K L D+++DY+DL+LIH+P + K E Sbjct: 83 DEGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEE 142 Query: 120 LMPTPEMLTKPD--------ITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVT 171 P D + TWKAME L GKA++IG+SNFS+ + DLL A + Sbjct: 143 KYPPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLRGAEIK 202 Query: 172 PAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVR-------LKVLQNPIVT 224 PAV Q+E HP QQ L E +S+G+ ++ YS G QS E++ + ++ +T Sbjct: 203 PAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKTIT 262 Query: 225 EVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQE 284 +A+K KT AQV LRW Q +++PKS++ RL +NL+V D+++ ++ F + S + Q+ Sbjct: 263 SIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLDQD 322 >3O3R-A nrPDB Length = 316 Score = 358 bits (920), Expect = 1e-99, Method: Composition-based stats. Identities = 121/313 (38%), Positives = 178/313 (56%), Gaps = 16/313 (5%) Query: 5 IRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 F +L T AK+P VGLGT+ V A++ AI GYRH DCA +Y NE E+G +++ Sbjct: 2 TTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQE 61 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKE-S 119 I + V+RE+LFI SKLWS + +A +KTL DL++DY+DLYLIHWP L+ Sbjct: 62 KIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGKE 121 Query: 120 LMPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPA 173 +P +++K W+ ME L D G +A+GVSNF+ ++ LLN + P Sbjct: 122 FLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 181 Query: 174 VNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKL 230 NQVECHP Q+ L + C SKG+ + YSPLGS + + + VL+ P + E+A K Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAKH 241 Query: 231 GKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF-SNIPQEKFCRA 289 KT AQV +R+ +Q +V+PKS + + +KEN+ VFD+ + E+ S + C Sbjct: 242 KKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACGL 301 Query: 290 TEFA-HETHGFYK 301 + E F++ Sbjct: 302 FVTSDEEDFPFHE 314 >3WCZ-A nrPDB Length = 308 Score = 358 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 99/300 (33%), Positives = 165/300 (55%), Gaps = 19/300 (6%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTYA----------MVATAIEQAIKIGYRHIDCASIYGN 50 MA +LN G +P V LGT V A+ AI+ GYRHID A++Y + Sbjct: 1 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 60 Query: 51 EKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIH 110 E+++G + + I +G V REELF+T+KLW++ H + V AL+++L+ L +DY+DLYLIH Sbjct: 61 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 120 Query: 111 WPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARV 170 +P + K + D TW+ M+ G AR+IGVSNF++ ++T L++ + + Sbjct: 121 FPIATKP------DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 174 Query: 171 TPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLG---SQSKGEVRLKVLQNPIVTEVA 227 P +NQ+E +P Q+ L C+S G+ + YSP G S+ + +P +T +A Sbjct: 175 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 234 Query: 228 EKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFC 287 K K+ Q+ LR+ + G +PKS++ R+ +N+D+FD+ + + + + Sbjct: 235 NKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRV 294 >1K8C-A nrPDB Length = 322 Score = 357 bits (917), Expect = 3e-99, Method: Composition-based stats. Identities = 121/304 (39%), Positives = 169/304 (55%), Gaps = 22/304 (7%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 56 M+A I +L++G +P +G G + A + QAIK GYR D A YGNEKE+G Sbjct: 1 MSASIPDIKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGD 60 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 +K+ I +G VKREE+F+TSKLW+N H P++V AL KTL DL++DYVDL+LIH+P + K Sbjct: 61 GVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120 Query: 117 K---ESLMP--------TPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLL 165 E P + I TWKA+E L +GK ++IGVSNF L DLL Sbjct: 121 FVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLL 180 Query: 166 NVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVR-------LKVL 218 A + PAV QVE HP QQ L E + GV ++ YS G QS E+ + Sbjct: 181 RGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLF 240 Query: 219 QNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF 278 + + +A K KT A+V LRW Q G +V+PKS+ RL +N + + ++ F + Sbjct: 241 AHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEI 300 Query: 279 SNIP 282 + + Sbjct: 301 AKLD 304 >1VBJ-A nrPDB Length = 281 Score = 346 bits (889), Expect = 5e-96, Method: Composition-based stats. Identities = 108/290 (37%), Positives = 152/290 (52%), Gaps = 31/290 (10%) Query: 5 IRFFELNTGAKLPCVGLGTYA-----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLK 59 + +L+ G +P +G G + TA AIK GYRHID A+IY NE+ G + Sbjct: 9 TQSLKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRAI- 67 Query: 60 KLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKES 119 V REELF+T+KLW++D E A EK+++ L ++YVDLYLIHWP Sbjct: 68 ---ASCGVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPG------ 118 Query: 120 LMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVEC 179 K TWKA E LY K RAIGVSNF + +LL +V P VNQ+E Sbjct: 119 ---------KDKFIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKHCKVAPMVNQIEL 169 Query: 180 HPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVAL 239 HP+ Q+ L E CKSK + ++ +SPLG ++++ + + K GKT AQV L Sbjct: 170 HPLLNQKALCEYCKSKNIAVTAWSPLGQGH-------LVEDARLKAIGGKYGKTAAQVML 222 Query: 240 RWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRA 289 RW +Q G +PKS + AR+KEN ++FD+ + + + Sbjct: 223 RWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHRYGP 272 >1VP5-A nrPDB Length = 298 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 109/297 (36%), Positives = 163/297 (54%), Gaps = 28/297 (9%) Query: 4 PIRFFELNTGAKLPCVGLGTYA----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLK 59 + LN G ++P +G G + + +AIK+GYR ID A+ Y NE+ +G +K Sbjct: 14 QVPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIK 73 Query: 60 KLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKES 119 + I +G V+REELF+T+KLW +D E KA EK+L+ LQ++Y+DLYLIH P Sbjct: 74 RAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG----- 128 Query: 120 LMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVEC 179 D+ WKAME +Y G RAIGVSNF +L DL+ + PAVNQ+E Sbjct: 129 -----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEI 177 Query: 180 HPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVAL 239 HP +Q+Q E ++ + + P E R + QN ++ +AEK GKT AQV L Sbjct: 178 HPFYQRQEEIEFMRNYNIQPEAWGPFA-----EGRKNIFQNGVLRSIAEKYGKTVAQVIL 232 Query: 240 RWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHET 296 RW Q G +PK+ R+KEN+ +FD+ + ++ K + + + + + F+H Sbjct: 233 RWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQ---SAFFSHRD 286 >4F40-A nrPDB Length = 288 Score = 341 bits (874), Expect = 3e-94, Method: Composition-based stats. Identities = 106/287 (36%), Positives = 148/287 (51%), Gaps = 23/287 (8%) Query: 8 FELNTGAKLPCVGLGTYA-----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 L+ G K+P GLG + + A++ A+ GYRHID A+IY NE+ +G L+ Sbjct: 13 VTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA-- 70 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMP 122 V RE++FIT+KLW+ + E A E++ Q L +DY+DLYLIHWP S Sbjct: 71 --SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKDILSKEG 128 Query: 123 TPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPV 182 +W+A E LY K RAIGVSNF L D+L + VTP VNQVE HP+ Sbjct: 129 K-------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPL 181 Query: 183 WQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWG 242 Q L C +K + + +SPLG K+L NPI++ + K KT AQV LRW Sbjct: 182 NNQADLRAFCDAKQIKVEAWSPLGQG-------KLLSNPILSAIGAKYNKTAAQVILRWN 234 Query: 243 LQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRA 289 +Q +PKS R++EN D+FD+ + + + Sbjct: 235 IQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSRYGP 281 >3KRB-A nrPDB Length = 334 Score = 337 bits (864), Expect = 5e-93, Method: Composition-based stats. Identities = 109/302 (36%), Positives = 163/302 (53%), Gaps = 26/302 (8%) Query: 17 PCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD--GFVKRE 70 P +G GT+ V TA+E A+ GYRHIDCA +Y NE+ IG K+ D +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 71 ELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK---ESLMPTPE-- 125 +++ITSKLW+ +H PE V + +KT+ DLQ+DY+DL+L+HWP + + L P Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 126 --MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVW 183 ML K + TW+AME L + G + IGVSN++ L DLLN A++ P VNQ+E HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWH 205 Query: 184 QQQGLHELCKSKGVHLSGYSPLGSQS------KGEVRLKVLQNPIVTEVAEKLGKTTAQV 237 + C G+ ++ YSP+G G + +L+ + +A+ G + V Sbjct: 206 PNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCV 265 Query: 238 ALRWGLQT----GHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEK---FCRAT 290 AL W ++ +SV+PKS + AR++ N + + +D +NI K FC Sbjct: 266 ALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIRFCDPA 325 Query: 291 EF 292 F Sbjct: 326 IF 327 >1QWK-A nrPDB Length = 317 Score = 335 bits (859), Expect = 2e-92, Method: Composition-based stats. Identities = 110/309 (35%), Positives = 174/309 (56%), Gaps = 23/309 (7%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 56 M++ +L+ G ++P +GLGT+ A V TA++ A+K GYR ID AS+Y NE+ IG Sbjct: 1 MSSATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGT 60 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 +K+L+ +G VKREELFIT+K W+++ P + L ++L+ LQ++YVDLYL H PA+ Sbjct: 61 AIKELLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN 120 Query: 117 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVN- 175 + E + + W+ +A+Y +G A+A+GVSN+++ +++ L + +TP N Sbjct: 121 DD----MSEHIAS-PVEDVWRQFDAVYKAGLAKAVGVSNWNNDQISRALAL-GLTPVHNS 174 Query: 176 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVR------------LKVLQNPIV 223 QVE H + Q + CK + ++ Y+ LGS + LQ+ V Sbjct: 175 QVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNV 234 Query: 224 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQ 283 +AEK KT AQV LR+ L G ++LPKS R+KEN +VFD+S+ E+ K Sbjct: 235 LALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEESKN 294 Query: 284 EKFCRATEF 292 + +F Sbjct: 295 SQRLFLQDF 303 >1MZR-A nrPDB Length = 296 Score = 333 bits (855), Expect = 5e-92, Method: Composition-based stats. Identities = 104/286 (36%), Positives = 157/286 (54%), Gaps = 28/286 (9%) Query: 8 FELNTGAKLPCVGLGTYA----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIG 63 +L G +P +GLG + V TAI++A+++GYR ID A+ Y NE+ +G LK Sbjct: 28 IKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALK---- 83 Query: 64 DGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPT 123 + V REELFIT+KLW++DH + +AL +L+ LQ+DY+DLYL+HWP Sbjct: 84 NASVNREELFITTKLWNDDH--KRPREALLDSLKKLQLDYIDLYLMHWPVP--------- 132 Query: 124 PEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVW 183 WK M L G ++IGV NF L L++ VTP +NQ+E HP+ Sbjct: 133 ----AIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLM 188 Query: 184 QQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGL 243 QQ+ LH + + +SPL KG V ++ ++A+K GKT AQ+ +RW L Sbjct: 189 QQRQLHAWNATHKIQTESWSPLAQGGKG-----VFDQKVIRDLADKYGKTPAQIVIRWHL 243 Query: 244 QTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRA 289 +G V+PKS + +R+ EN DV+D+ + +D + + + Q K Sbjct: 244 DSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRLGP 289 >4MHB-A nrPDB Length = 297 Score = 326 bits (835), Expect = 1e-89, Method: Composition-based stats. Identities = 103/300 (34%), Positives = 153/300 (51%), Gaps = 33/300 (11%) Query: 2 AAPIRFFELNTGAKLPCVGLGTY-----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGG 56 ++ +LN G +P +G G + A A+ AI+ GYR ID A+ Y NE ++G Sbjct: 12 DNVMQTVKLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGN 71 Query: 57 VLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK 116 LK + R+ELFIT+KLW D E E++L LQ+DYVDLYLIH P Sbjct: 72 ALKL----SGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPYG-- 125 Query: 117 KESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQ 176 D+ W+AME L+ +GK RAIGVSNF +L DL+ ++ PAVNQ Sbjct: 126 --------------DVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFNKIIPAVNQ 171 Query: 177 VECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQ 236 +E +P QQ +S+G+ ++P G + QNP++T + EK GK+ Q Sbjct: 172 IEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRNG-----LFQNPVLTAIGEKYGKSVGQ 226 Query: 237 VALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHET 296 V LRW Q G L KS R++EN+++ D+ + + + + + + F+H Sbjct: 227 VVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALDTA---TSAFFSHRD 283 >3D3F-A nrPDB Length = 275 Score = 319 bits (818), Expect = 9e-88, Method: Composition-based stats. Identities = 114/288 (39%), Positives = 162/288 (56%), Gaps = 31/288 (10%) Query: 8 FELNTGAKLPCVGLGTYA-----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 62 +L+ G ++P GLG + +++ AIK GYR ID A+IY NE+ +G +K+ Sbjct: 8 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKE-- 65 Query: 63 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMP 122 V REELFITSK+W+ D E A EK+L+ LQ+DY+DLYLIHWP Sbjct: 66 --SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPG--------- 114 Query: 123 TPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPV 182 K TW+A+E LY GK RAIGVSNF L +LL A + P VNQVE HP Sbjct: 115 ------KDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPR 168 Query: 183 WQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWG 242 Q+ L + CK +G+ L +SPL ++ ++L N ++T++AEK K+ AQV LRW Sbjct: 169 LTQKELRDYCKGQGIQLEAWSPL-------MQGQLLDNEVLTQIAEKHNKSVAQVILRWD 221 Query: 243 LQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRAT 290 LQ G +PKS R+ EN D+FD+ + ++ K + +++ Sbjct: 222 LQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERVGPN 269 >4OTK-A nrPDB Length = 318 Score = 308 bits (789), Expect = 2e-84, Method: Composition-based stats. Identities = 100/291 (34%), Positives = 138/291 (47%), Gaps = 28/291 (9%) Query: 2 AAPIRFFELNTGAKLPCVGLGTYA----MVATAIEQAIKIGYRHIDCASIYGNEKEIGGV 57 AA LN +P +GLG A+ A++IG R ID A YGNE +G Sbjct: 43 AAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRA 102 Query: 58 LKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK 117 + V REELF+T+KL + D +A +L L +DYVDLYLIHWPA Sbjct: 103 I----AASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPAP--- 155 Query: 118 ESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQV 177 W M G AR+IGVSNF+++ + +L+++ VTPAVNQ+ Sbjct: 156 ----------PVGKYVDAWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTFVTPAVNQI 205 Query: 178 ECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQV 237 E HP+ Q L + V Y PL +L NP VT +A + KT AQV Sbjct: 206 ELHPLLNQDELRKANAQHTVVTQSYCPLALGR-------LLDNPTVTSIASEYVKTPAQV 258 Query: 238 ALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCR 288 LRW LQ G++V+ +S+ R+ N DVFD+ + + + R Sbjct: 259 LLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRVR 309 >4IJC-A nrPDB Length = 344 Score = 304 bits (778), Expect = 4e-83, Method: Composition-based stats. Identities = 103/316 (32%), Positives = 161/316 (50%), Gaps = 37/316 (11%) Query: 7 FFELNTGAKLPCVGLGT------YAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 +F LN G ++P +GLGT A A++ AIK GYRHID A Y E +G +K+ Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK---- 116 L+ DG +KRE+LFIT+K+W L ++V ++L ++L+ L ++YVDL L HWP + Sbjct: 84 LLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 117 ----------KESLMPTPEMLTKPDITSTWKAMEALY---DSGKARAIGVSNFSSKKLTD 163 D T+K +E +Y + + RAIGVSNFS + L Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 Query: 164 LLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIV 223 L+ RV P VNQVE HP Q L + C + L+ YSPLGS L+ P+V Sbjct: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-----LKIPLV 256 Query: 224 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDW-SIPEDLFTKFSNIP 282 ++AEK T + + + ++ G V+P+S + R+ +++ + S+ +D + ++ Sbjct: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE---FASLTKDELQELNDFG 313 Query: 283 QEKFCRATEFAHETHG 298 ++ R F E Sbjct: 314 EKYPVR---FIDEPFA 326 >1A80-A nrPDB Length = 277 Score = 296 bits (759), Expect = 6e-81, Method: Composition-based stats. Identities = 97/282 (34%), Positives = 143/282 (50%), Gaps = 26/282 (9%) Query: 5 IRFFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60 + LN G +P +G G + A A+E+A+++GYRHID A+IYGNE+ + Sbjct: 2 VPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGV----GA 57 Query: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 120 I + R++LFIT+KLW++ H ++ A+ ++L L +D VDLYL+HWP Sbjct: 58 AIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTP------ 111 Query: 121 MPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECH 180 + W+ M L +G R+IGVSN L ++ V PAVNQ+E H Sbjct: 112 -------AADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELH 164 Query: 181 PVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALR 240 P +QQ+ + + + V + + PLG + + VT A GKT AQ LR Sbjct: 165 PAYQQREITDWAAAHDVKIESWGPLGQG-----KYDLFGAEPVTAAAAAHGKTPAQAVLR 219 Query: 241 WGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIP 282 W LQ G V PKS RL+ENLDVFD+ + + + Sbjct: 220 WHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMD 261 >3WG6-A nrPDB Length = 307 Score = 289 bits (741), Expect = 8e-79, Method: Composition-based stats. Identities = 96/317 (30%), Positives = 162/317 (51%), Gaps = 40/317 (12%) Query: 1 MAAPIRFFELNTGAKLPCVGLGTY------------AMVATAIEQAIKIGYRHIDCASIY 48 M+ + F+L+ G K+P V GT + +E A++ G+RHID A IY Sbjct: 4 MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 63 Query: 49 GNEKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLPE-------DVPKALEKTLQDLQI 101 G KEIG LK + + R+++FIT K S +H + + AL+ L+DL + Sbjct: 64 GTNKEIGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 119 Query: 102 DYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKL 161 +YVDLYLIH+P +K D+ W+ +E + G AR IGVSNF+ + L Sbjct: 120 EYVDLYLIHFPYISEKSHGF---------DLVEAWRYLERAKNEGLARNIGVSNFTIENL 170 Query: 162 TDLLNVARVT-PAVNQVECHPVWQQQ--GLHELCKSKGVHLSGYSPLGSQSKGEVRLKVL 218 +L+ + P VNQ+E Q Q G+ E + +G+ + Y PLG ++G Sbjct: 171 KSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGPL-- 228 Query: 219 QNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKF 278 + ++++++EK + Q+ LRW LQ G + +S R+ + L++FD+ + ++ + Sbjct: 229 -DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDEDQI 287 Query: 279 SNIPQEKFCRATEFAHE 295 + + +EK R +F+ E Sbjct: 288 TKVGKEKTLR--QFSKE 302 >3UP8-A nrPDB Length = 298 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 92/292 (31%), Positives = 160/292 (54%), Gaps = 32/292 (10%) Query: 11 NTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGF 66 + GA +P +G GT+ A V + QA+K+G+RH+D A IYGNE E+G ++K Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQK----SG 84 Query: 67 VKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEM 126 + R ++F+T+K+W +++ + +++++L+ L+ D+VDL L+HWP S +P E Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWP-----GSDVPMAER 139 Query: 127 LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQQ 186 + A+ + ++GK R IG+SNF++ ++ + ++ A NQVE HP Q Sbjct: 140 IG---------ALNEVRNAGKVRHIGISNFNTTQMEEAARLSDAPIATNQVEYHPYLDQT 190 Query: 187 GLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGL-QT 245 + + + G+ L+ Y + + KV +P++TE+ + GKT AQVALRW + Q Sbjct: 191 KVLQTARRLGMSLTSYYAMANG-------KVPADPLLTEIGGRHGKTAAQVALRWLVQQQ 243 Query: 246 GHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNI--PQEKFCRATEFAHE 295 VL K+++ ARLKEN +FD+++ + + P + A E Sbjct: 244 DVIVLSKTATEARLKENFAIFDFALTREEMAAVRELARPNGRIVNPQGLAPE 295 >4H8N-A nrPDB Length = 310 Score = 273 bits (698), Expect = 8e-74, Method: Composition-based stats. Identities = 95/311 (30%), Positives = 146/311 (46%), Gaps = 38/311 (12%) Query: 6 RFFELNTGAKLP-CVGLGT-YAMVATA----------IEQAIKIGYRHIDCASIYGNEKE 53 + F +G ++ +G GT + T I +K+G+RHID A Y +KE Sbjct: 12 KTFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKE 71 Query: 54 IGGVLKKLIGDGFVKREELFITSKL---WSNDHLPEDVPK-ALEKTLQDLQIDYVDLYLI 109 +G LK+ V RE++++T+K W + P +++K L L +DYVDL+LI Sbjct: 72 VGEALKRTD----VPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLI 127 Query: 110 HWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNV-- 167 H P T E + W+A+ +GK R IG+SN + L L Sbjct: 128 HSP--------FFTTEQTHGYTLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLFAASP 179 Query: 168 -ARVTPAVNQVECHPVWQQQ--GLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVT 224 P VNQ+E HP Q Q + C+ G+ + +SPL ++ E + Sbjct: 180 SPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPLARVETNALA---ETLK 236 Query: 225 EVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQE 284 +AEK KT AQV LR+ LQ G + SS +RLKE+L++FD+ + ++ + + I Sbjct: 237 RLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNEINKIGDA 296 Query: 285 KFCRATEFAHE 295 RA F HE Sbjct: 297 NPYRA--FFHE 305 >1LQA-A nrPDB Length = 346 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 76/341 (22%), Positives = 135/341 (39%), Gaps = 63/341 (18%) Query: 11 NTGAKLPCVGLGTY--------AMVATAIEQAIKIGYRHIDCASIYG--NEKEIGGVLKK 60 ++ ++ +GLGT A ++ A+ G ID A +Y E G+ + Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 61 LIGDGFVK---REELFITSKL----WSNDHL--------PEDVPKALEKTLQDLQIDYVD 105 +G+ K RE+L I SK+ +ND +++ +AL +L+ LQ DY+D Sbjct: 68 YVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD 127 Query: 106 LYLIHWPASLKK---ESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLT 162 LY +HWP + + + T A+ +GK R IGVSN ++ + Sbjct: 128 LYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVM 187 Query: 163 DLLN------VARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLG---------- 206 L+ + R+ N + GL E+ + +GV L YS LG Sbjct: 188 RYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLN 247 Query: 207 ---------------SQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTGHS--V 249 ++ GE K + + ++A + G AQ+AL + + Sbjct: 248 GAKPAGARNTLFSRFTRYSGEQTQKAVAAYV--DIARRHGLDPAQMALAFVRRQPFVAST 305 Query: 250 LPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRAT 290 L +++ +LK N++ + ED+ + + Q A Sbjct: 306 LLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTYPAP 346 >3EB3-A nrPDB Length = 327 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 76/335 (22%), Positives = 135/335 (40%), Gaps = 78/335 (23%) Query: 12 TGAKLPCVGLGTYAMVATAIE---------QAIKIGYRHIDCASIYGNEKE---IGGVLK 59 +G ++ C+GLGT+ I A G D A +Y K +G ++K Sbjct: 11 SGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIK 70 Query: 60 KLIGDGFVKREELFITSKLWSNDHLP-------EDVPKALEKTLQDLQIDYVDLYLIHWP 112 K +R L IT+K+++ + + + L+ +L+ LQ++YVD+ + P Sbjct: 71 KK----GWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 126 Query: 113 ASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVAR--- 169 + T +AM + + G A G S +SS ++ + +VAR Sbjct: 127 DP--------------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 172 Query: 170 -VTPAVNQVECHPVWQQQ---GLHELCKSKGVHLSGYSPLGSQ-------------SKGE 212 + P Q E H +++ L EL GV +SPL S+ Sbjct: 173 LIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRAS 232 Query: 213 VR-LKVLQNPIVTE--------------VAEKLGKTTAQVALRWGLQTG--HSVLPKSSS 255 ++ + L++ I++E +AE+LG T Q+A+ W L+ SVL +S+ Sbjct: 233 LKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASN 292 Query: 256 GARLKEN---LDVFDWSIPEDLFTKFSNIPQEKFC 287 +L EN + V + + + +I K Sbjct: 293 AEQLMENIGAIQVLP-KLSSSIVHEIDSILGNKPY 326 >3N6Q-A nrPDB Length = 346 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 72/345 (20%), Positives = 146/345 (42%), Gaps = 83/345 (24%) Query: 1 MAAPIRFFELN------TGAKLPCVGLGTYAMVA---------TAIEQAIKIGYRHIDCA 45 +A P R+ ++ +G +LP + LG + + +A +G H D A Sbjct: 4 LANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLA 63 Query: 46 SIYG-----NEKEIGGVLKKLIGDGFVKREELFITSK----LWSNDHLPEDVPK----AL 92 + YG E+ G +L++ D R+EL I++K +W + K +L Sbjct: 64 NNYGPPPGSAEENFGRLLRE---DFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL 120 Query: 93 EKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIG 152 +++L+ + ++YVD++ H + P T A+ SGKA +G Sbjct: 121 DQSLKRMGLEYVDIFYSHR-----VDENTPM---------EETASALAHAVQSGKALYVG 166 Query: 153 VSNFSSK---KLTDLLNVARVTPAVNQVECHPVWQ---QQGLHELCKSKGVHLSGYSPL- 205 +S++S + K+ +LL ++ ++Q + + + + GL + ++ GV ++PL Sbjct: 167 ISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLA 226 Query: 206 ---------------------GSQSKGEVRLKVLQNP------IVTEVAEKLGKTTAQVA 238 G++ +G + K+L ++ E+A++ G++ AQ+A Sbjct: 227 QGLLTGKYLNGIPQDSRMHREGNKVRG-LTPKMLTEANLNSLRLLNEMAQQRGQSMAQMA 285 Query: 239 LRWGLQ--TGHSVLPKSSSGARLKENLDVF-DWSIPEDLFTKFSN 280 L W L+ SVL +S +L+EN+ + + + Sbjct: 286 LSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQ 330 >1OG6-A nrPDB Length = 298 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 72/280 (25%), Positives = 107/280 (38%), Gaps = 45/280 (16%) Query: 25 AMVATAIEQAIKIGYRHIDCASIYGN---EKEIGGVLK------------KLIGDGFVKR 69 + + IE+ + +G +D A IYG E G LK G R Sbjct: 32 RQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAR 91 Query: 70 EELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTK 129 EE I + DH + K+ E++L +L D++DL LIH P L Sbjct: 92 EENVIGHYITDRDH----IIKSAEQSLINLATDHLDLLLIHRPDPLM------------- 134 Query: 130 PDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQ---Q 186 D A + L+ SGK R GVSNF+ + L + T A NQVE PV Q Sbjct: 135 -DADEVADAFKHLHQSGKVRHFGVSNFTPAQFALLQSRLPFTLATNQVEISPVHQPLLLD 193 Query: 187 GLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEV---AEKLGK-TTAQVALRWG 242 G + + V +S LG G + P+ E+ AE+L + QV W Sbjct: 194 GTLDQLQQLRVRPMAWSCLGG---GRLFNDDYFQPLRDELAVVAEELNAGSIEQVVNAWV 250 Query: 243 LQTGHSVLP--KSSSGARLKENLDVFDWSIPEDLFTKFSN 280 L+ LP S R++ ++ + + + Sbjct: 251 LRLPSQPLPIIGSGKIERVRAAVEAETLKMTRQQWFRIRK 290 >4R9O-A nrPDB Length = 301 Score = 170 bits (431), Expect = 7e-43, Method: Composition-based stats. Identities = 66/278 (23%), Positives = 108/278 (38%), Gaps = 41/278 (14%) Query: 25 AMVATAIEQAIKIGYRHIDCASIYGN---EKEIGGVLK------------KLIGDGFVKR 69 + + IE+ + +G +D A IYG E G L G R Sbjct: 35 RQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTKCGIATTAR 94 Query: 70 EELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTK 129 E + + H + + E++L++L DY+D+ LIH P L Sbjct: 95 AENKLGHYITDRRH----IILSAEQSLKNLATDYLDMLLIHRPDPLM------------- 137 Query: 130 PDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQ---Q 186 D +A + L+ SGK R GVSNF+ + T L + T A NQVE PV Q Sbjct: 138 -DADDVAEAFQHLHQSGKVRHFGVSNFTPAQFTLLQSRLPFTLATNQVEISPVHQPLLLD 196 Query: 187 GLHELCKSKGVHLSGYSPLGSQS-KGEVRLKVLQNPIVTEVAEKLGK-TTAQVALRWGLQ 244 G + + + +S LG + + L+ ++ +A++L + QV W L+ Sbjct: 197 GTLDQLQQLRIRPMAWSCLGGGRLFNDEAYQPLRQE-LSVIAQELNASSIEQVVYAWILR 255 Query: 245 TGHSVLP--KSSSGARLKENLDVFDWSIPEDLFTKFSN 280 LP S R++ L+ S+ + + Sbjct: 256 LPSQPLPIIGSGKIERVRAALEAETLSLTRQQWFRIRK 293 >1PZ1-A nrPDB Length = 333 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 78/335 (23%), Positives = 135/335 (40%), Gaps = 81/335 (24%) Query: 11 NTGAKLPCVGLGTYAMVAT------------AIEQAIKIGYRHIDCASIYG---NEKEIG 55 +TG + +GLGT+A+ T I A+ G ID A YG +E+ +G Sbjct: 8 DTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVG 67 Query: 56 GVLKKLIGDGFVKREELFITSKL---WSNDHLPEDVPKA-----LEKTLQDLQIDYVDLY 107 +K+ + KR+++ + +K W N+ L +A +E +L+ LQ DY+DLY Sbjct: 68 KAIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLY 122 Query: 108 LIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNV 167 +HWP L I T + M+ LYD+GK RAIGVSNFS +++ V Sbjct: 123 QVHWPDPLVP--------------IEETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAV 168 Query: 168 A---RVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPI-- 222 A + P N E ++ + K + Y GS +G + K+ + Sbjct: 169 APLHTIQPPYNLFEREM---EESVLPYAKDNKITTLLY---GSLCRGLLTGKMTEEYTFE 222 Query: 223 -------------------------VTEVAE-KLGKTTAQVALRWGLQTG--HSVLPKSS 254 + ++A+ + GK+ +A+RW L L + Sbjct: 223 GDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADIALWGAR 282 Query: 255 SGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRA 289 +L+ ++ W++ + + I + Sbjct: 283 KPGQLEALSEITGWTLNSEDQKDINTILENTISDP 317 >1PYF-A nrPDB Length = 312 Score = 166 bits (421), Expect = 1e-41, Method: Composition-based stats. Identities = 67/315 (21%), Positives = 124/315 (39%), Gaps = 74/315 (23%) Query: 19 VGLGTYA-------------MVATAIEQAIKIGYRHIDCASIYG---NEKEIGGVLKKLI 62 +GLGT A + +AI+ G +D A IYG +E+ IG VL++ Sbjct: 16 IGLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF- 74 Query: 63 GDGFVKREELFITSKL--------WSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPAS 114 RE++ I +K + D+ P+ + K+++++L+ L DY+DL+ IH+P Sbjct: 75 -----NREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP-- 127 Query: 115 LKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAV 174 + P E + A+ + +GK R+IGVSNFS ++L + V V Sbjct: 128 ---DEHTPKDEAVN---------ALNEMKKAGKIRSIGVSNFSLEQLKEANKDGLVD--V 173 Query: 175 NQVECHPVWQQQG--LHELCKSKGVHLSGYSPLGSQSKG--------------------- 211 Q E + + ++ K + Y PL S Sbjct: 174 LQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVSGLLAGKYTEDTTFPEGDLRNEQEHF 233 Query: 212 ---EVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTG--HSVLPKSSSGARLKENLDVF 266 + + + + +AEK + L W L ++P + +L +N+ Sbjct: 234 KGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDILIPGAKRADQLIDNIKTA 293 Query: 267 DWSIPEDLFTKFSNI 281 D ++ ++ + + Sbjct: 294 DVTLSQEDISFIDKL 308 >1GVE-A nrPDB Length = 327 Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats. Identities = 57/285 (20%), Positives = 107/285 (37%), Gaps = 63/285 (22%) Query: 28 ATAIEQAIKIGYRHIDCASIYGN--EKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLP 85 + ++ ++ G+ ID A +Y N + I G L +G K + + ++ P Sbjct: 25 SASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATKAAPMFGKTLKP 84 Query: 86 EDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDS 145 DV LE +L+ LQ VDL+ +H+P I T +A L+ Sbjct: 85 ADVRFQLETSLKRLQCPRVDLFYLHFPDH--------------GTPIEETLQACHQLHQE 130 Query: 146 GKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHELCKSKGVHL 199 GK +G+SN+ S ++ ++ + + + P V Q + + +Q L + G+ Sbjct: 131 GKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRF 190 Query: 200 SGYSPLG-------------------SQSKGEVRLKVLQNP------------IVTEVAE 228 ++PL S+ G ++ + + + Sbjct: 191 YAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKEEHFNGIALVEKALKT 250 Query: 229 KLGKTTAQV---ALRW---GLQ----TGHSVLPKSSSGARLKENL 263 G T + A+RW Q G +V+ SS +L++NL Sbjct: 251 TYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNL 295 >2CLP-A nrPDB Length = 347 Score = 136 bits (343), Expect = 1e-32, Method: Composition-based stats. Identities = 55/285 (19%), Positives = 104/285 (36%), Gaps = 63/285 (22%) Query: 28 ATAIEQAIKIGYRHIDCASIY--GNEKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLP 85 A ++ G+ ID A +Y G + I G L +G + + L+ N P Sbjct: 45 AAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKP 104 Query: 86 EDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDS 145 + + LE +L+ LQ VDL+ +H P + T +A L+ Sbjct: 105 DSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP--------------VEETLRACHQLHQE 150 Query: 146 GKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHELCKSKGVHL 199 GK +G+SN+++ ++ ++ + + + P V Q + + +Q L + G+ Sbjct: 151 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRF 210 Query: 200 SGYSPLGSQ-------------------SKGEVRLKVLQNP------------IVTEVAE 228 ++PL G ++ +N + + Sbjct: 211 YAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQA 270 Query: 229 KLGKTTAQV---ALRW-----GLQ--TGHSVLPKSSSGARLKENL 263 G + + LRW LQ G +V+ SS +L++NL Sbjct: 271 AYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNL 315 >2C91-A nrPDB Length = 338 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 64/304 (21%), Positives = 110/304 (36%), Gaps = 71/304 (23%) Query: 17 PCVGLGTYAMVAT--------AIEQAIKIGYRHIDCASIY--GNEKEIGGVLKKLIGDGF 66 P LGT M ++ ++ G+ +D A +Y G + I G L +G G Sbjct: 17 PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGD 76 Query: 67 VKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEM 126 + + P+ + LE +L+ LQ VDL+ +H P Sbjct: 77 CTVKIATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAPDHSTP--------- 127 Query: 127 LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPV 182 + T A L+ GK +G+SN++S ++ ++ + + + P V Q + Sbjct: 128 -----VEETLCACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 182 Query: 183 WQQ--QGLHELCKSKGVHLSGYSPLGSQ---SKGEVRLKVLQNPI--------------- 222 +Q L + G+ Y+PL K + K + P+ Sbjct: 183 TRQVEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNNWAETYRNR 242 Query: 223 ------VTEVA--EK-----LGKTTAQV---ALRW-----GLQ--TGHSVLPKSSSGARL 259 +A EK G ++ ALRW LQ G +V+ SS +L Sbjct: 243 FWKEHHFEAIALVEKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQL 302 Query: 260 KENL 263 ++NL Sbjct: 303 EQNL 306 >2BP1-A nrPDB Length = 360 Score = 126 bits (316), Expect = 2e-29, Method: Composition-based stats. Identities = 60/282 (21%), Positives = 104/282 (36%), Gaps = 69/282 (24%) Query: 34 AIKIGYRHIDCASIY--GNEKEIGGVLKKLIGDGFVKREELFITSKL--WSND-HLPEDV 88 ++ G+ +D A +Y G + I G L +G G + + I +K W P+ V Sbjct: 64 FLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKANPWDGKSLKPDSV 120 Query: 89 PKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKA 148 LE +L+ LQ VDL+ +H P + T A + L+ GK Sbjct: 121 RSQLETSLKRLQCPQVDLFYLHAPDH--------------GTPVEETLHACQRLHQEGKF 166 Query: 149 RAIGVSNFSSKKLTDLLNVAR----VTPAVNQVECHPVWQQ--QGLHELCKSKGVHLSGY 202 +G+SN++S ++ ++ + + + P V Q + +Q L + G+ Y Sbjct: 167 VELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAY 226 Query: 203 SPLGSQ-------------------SKGEVRLKVLQNP------------IVTEVAEKLG 231 +PL G + +N + + G Sbjct: 227 NPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYG 286 Query: 232 KTTAQV---ALRW-----GLQ--TGHSVLPKSSSGARLKENL 263 + V ALRW LQ G +V+ SS +L++NL Sbjct: 287 ASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNL 328 >4EXA-A nrPDB Length = 292 Score = 63.8 bits (154), Expect = 8e-11, Method: Composition-based stats. Identities = 46/237 (19%), Positives = 86/237 (36%), Gaps = 58/237 (24%) Query: 11 NTGAKLPCVGLGTYA-------------------MVATAIEQAIKIGYRHIDCASIYG-N 50 +TG + +GLGT A + A +G ID A YG + Sbjct: 37 DTGLAVSPLGLGTVKFGRDQGVKYPSGFTIPDDREAADLLALARDLGINLIDTAPAYGRS 96 Query: 51 EKEIGGVLKKLIGDGFVKREELFITSKL--------WSNDHLPEDVPKALEKTLQDLQID 102 E+ +G +L+ +RE I SK+ D +++E++L+ L+ D Sbjct: 97 EERLGPLLRG-------QREHWVIVSKVGEEFVDGQSVFDFSAAHTRRSVERSLKRLETD 149 Query: 103 YVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLT 162 ++L L+H L + + + + AL G A G+S + + Sbjct: 150 RIELVLVH-----------SDGNDLDILENSEVYPTLAALKREGLIGAYGLSGKTVEGGL 198 Query: 163 DLLNVARVTPAVNQVECHPVWQ-QQGLHEL--CKSKGVHL-----SGYSPLGSQSKG 211 L V + + ++ + E +KG+ + SG++ LG+ Sbjct: 199 RALREGD----CAMVTYNLNERAERPVIEYAAAHAKGILVKKALASGHACLGAGQDP 251 >1TMO-A nrPDB Length = 829 Score = 31.8 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 20/168 (11%), Positives = 51/168 (30%), Gaps = 41/168 (24%) Query: 111 WPASLKKESLMPTPEMLTKPDITSTWKA-----------MEALYDSGKARAIGVSNFSSK 159 WP L+ + ++ W A ++ GK R I Sbjct: 204 WPLILEHSDTIVLWSNDPYKNLQVGWNAETHESFAYLAQLKEKVKQGKIRVI-------- 255 Query: 160 KLTDLLNVARVTPAVNQVECHPVWQ------------QQGLHE--LCKSKGVHLSGYSP- 204 + ++ + Q+ +P + L++ + + + P Sbjct: 256 SIDPVVTKTQAYLGCEQLYVNPQTDVTLMLAIAHEMISKKLYDDKFIQGYSLGFEEFVPY 315 Query: 205 -LGSQSKGEVRLKV------LQNPIVTEVAEKLGKTTAQVALRWGLQT 245 +G++ + ++ ++ ++A+ L K Q + W +Q Sbjct: 316 VMGTKDGVAKTPEWAAPICGVEAHVIRDLAKTLVKGRTQFMMGWCIQR 363 >1BE1-A nrPDB Length = 137 Score = 31.0 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 34/87 (39%), Gaps = 4/87 (4%) Query: 18 CVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGFVKREELFITSK 77 V +G + I AI+ I +S+YG + L++ + +K +LF+ Sbjct: 34 VVNIGVLSSQEDFINAAIETKADLICVSSLYGQGEIDCKGLREKCDEAGLKGIKLFVGGN 93 Query: 78 LWSNDHLPEDVPKALEKTLQDLQIDYV 104 + DV E+ + + D V Sbjct: 94 IVVGKQNWPDV----EQRFKAMGFDRV 116 >5GZ9-A nrPDB Length = 305 Score = 30.7 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 29/129 (22%), Positives = 45/129 (34%), Gaps = 14/129 (10%) Query: 188 LHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQV-ALRWGLQTG 246 L C+ G L+ Y PLGS S E L++ + V +L V + + + Sbjct: 92 LVGYCEEDGTILTEYHPLGSLSNLEETLQLSKYQDVNTWQHRLQLAMEYVSIINYLHHSP 151 Query: 247 HSV--------LPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHG 298 LPK+ S L N +SI + + + E HG Sbjct: 152 LGTRVMCDSNDLPKTLSQYLLTSN-----FSIVANDLDALPLVDHDSGVLIKCGHRELHG 206 Query: 299 FYKTIEELW 307 + E+LW Sbjct: 207 DFVAPEQLW 215 >4EHI-A nrPDB Length = 534 Score = 30.7 bits (68), Expect = 0.96, Method: Composition-based stats. Identities = 7/18 (38%), Positives = 11/18 (61%) Query: 39 YRHIDCASIYGNEKEIGG 56 ++HID +Y N E+G Sbjct: 383 FKHIDGGFVYQNSDEVGE 400 >3Q3N-A nrPDB Length = 500 Score = 29.1 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 17/31 (54%), Gaps = 3/31 (9%) Query: 81 NDHLPEDVPKALEKTLQDLQID---YVDLYL 108 + + E + E++L DL +D Y DL+L Sbjct: 291 KEFMYEWIIGQFERSLIDLGLDKPWYWDLFL 321 >5AZD-A nrPDB Length = 268 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 2/32 (6%) Query: 20 GLGTYAMVATAIEQAIKIGYRHIDCAS--IYG 49 LGT+ A E AI+IGY D + IYG Sbjct: 206 ALGTWLPGGAAQEVAIQIGYSLADLIAKPIYG 237 >2P1I-A nrPDB Length = 349 Score = 29.1 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 24/65 (36%), Gaps = 3/65 (4%) Query: 247 HSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFYKTIE-E 305 + KS+S ++ ++ D+ ++ K N +F E FYK E Sbjct: 4 VVNISKSASFSKQEKEFS--DFQKSKESNEKILNKESNRFTLHPIMYPEVWNFYKKAEAS 61 Query: 306 LWDGE 310 W E Sbjct: 62 FWTAE 66 >2WUA-A nrPDB Length = 440 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%), Gaps = 4/45 (8%) Query: 197 VHLSGY-SPLGSQSKGEVR---LKVLQNPIVTEVAEKLGKTTAQV 237 V ++ Y SPL +G ++ + P++ + EK A+V Sbjct: 36 VIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEV 80 >6O81-C nrPDB Length = 368 Score = 28.7 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 22/66 (33%), Gaps = 2/66 (3%) Query: 135 TWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQQGLHELCKS 194 +A+E ++ + IG S L + + V EC P Q + Sbjct: 169 AAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIV--AECAPFCQGHEMAVNLSK 226 Query: 195 KGVHLS 200 G+ + Sbjct: 227 AGIETT 232 >4FO0-A nrPDB Length = 593 Score = 28.7 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 23/58 (39%), Gaps = 5/58 (8%) Query: 77 KLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITS 134 K + H PE + + L ++ +D Y IHWP + ++ P P + Sbjct: 124 KWTNTSHHPEYLVGE-----EALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLAD 176 >2AXQ-A nrPDB Length = 467 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 28/76 (36%), Gaps = 5/76 (6%) Query: 22 GT--YAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGFVKREELF--ITSK 77 GT Y ++ + +G D I+ LK+ +G +E+L I SK Sbjct: 264 GTLRYQGFPEFVKALVDMGMLKDDANEIFSKPIAWNEALKQYLGAKSTSKEDLIASIDSK 323 Query: 78 L-WSNDHLPEDVPKAL 92 W +D E + Sbjct: 324 ATWKDDEDRERILSGF 339 >5EY9-A nrPDB Length = 629 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 70 EELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTK 129 ++L I +H P+D+ +++ + L++ YV + + PA+ + + P Sbjct: 484 KDLVIID---GRNHYPQDLEYTAQESTKALRVGYVAAFSV--PANQLPQKVFDDPHAGLS 538 Query: 130 PDITSTWKAM 139 D T + + Sbjct: 539 FDPEDTSEQL 548 >4YWJ-A nrPDB Length = 276 Score = 28.4 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 19/40 (47%) Query: 135 TWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAV 174 T K +E + +A IG + FS+ + L A+ P V Sbjct: 90 TLKNIEQCRKARRAMVIGTTGFSADEKLLLAEAAKDIPIV 129 >1JPH-A nrPDB Length = 388 Score = 28.0 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 41 HIDCASIYGNEKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDV 88 ++D ++Y +E+EIG ++K+++ D R + L+ D PE V Sbjct: 325 NLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYP-DMDPEHV 371 >2B0D-A nrPDB Length = 245 Score = 27.6 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 204 PLGSQSKGEVR-LKVLQNPIVTEVAEKLG 231 PLGS +K ++ PI+ ++AEK G Sbjct: 32 PLGSDTKVLSTIFELFSRPIINKIAEKHG 60 >2GE5-A nrPDB Length = 219 Score = 27.6 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 204 PLGSQSKGEVR-LKVLQNPIVTEVAEKLG 231 PLGS +K ++ PI+ ++AEK G Sbjct: 31 PLGSDTKVLSTIFELFSRPIINKIAEKHG 59 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.147 0.443 Lambda K H 0.267 0.0451 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,974,650 Number of Sequences: 36641 Number of extensions: 623591 Number of successful extensions: 2228 Number of sequences better than 10.0: 70 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1745 Number of HSP's gapped (non-prelim): 134 length of query: 311 length of database: 10,336,785 effective HSP length: 97 effective length of query: 214 effective length of database: 6,782,608 effective search space: 1451478112 effective search space used: 1451478112 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.2 bits)