BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O77059 (542 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4JZY-A nrPDB 1109 0.0 4I6J-A nrPDB 377 e-104 4K0R-A nrPDB 373 e-104 3FY4-A nrPDB 335 4e-92 4U63-A nrPDB 162 4e-40 1OWP-A nrPDB 160 1e-39 2E0I-A nrPDB 149 3e-36 1NP7-A nrPDB 146 2e-35 1DNP-A nrPDB 122 4e-28 1U3C-A nrPDB 111 8e-25 2VTB-B nrPDB 101 6e-22 2J08-A nrPDB 77 2e-14 5O8D-A nrPDB 34 0.18 5WAB-A nrPDB 33 0.40 4ADI-A nrPDB 31 1.5 5H12-A nrPDB 28 7.7 >4JZY-A nrPDB Length = 536 Score = 1109 bits (2869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/540 (99%), Positives = 535/540 (99%), Gaps = 5/540 (0%) Query: 1 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL 60 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL Sbjct: 2 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL 61 Query: 61 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES 120 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES Sbjct: 62 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES 121 Query: 121 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL 180 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL Sbjct: 122 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL 181 Query: 181 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV 240 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV Sbjct: 182 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV 241 Query: 241 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGV 300 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQL GV Sbjct: 242 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQL-----GV 296 Query: 301 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 360 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF Sbjct: 297 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 356 Query: 361 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 420 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW Sbjct: 357 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 416 Query: 421 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 480 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ Sbjct: 417 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 476 Query: 481 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADV 540 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADV Sbjct: 477 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADV 536 >4I6J-A nrPDB Length = 544 Score = 377 bits (967), Expect = e-104, Method: Compositional matrix adjust. Identities = 216/526 (41%), Positives = 301/526 (57%), Gaps = 42/526 (7%) Query: 1 MATRGANVI-WFRHGLRLHDNPALLAALADKDQGIALIP-VFIFDGESAGTKNVGYNRMR 58 M GA+ + WFR GLRLHDNPALLAA+ +G + V+I D A + +VG NR R Sbjct: 16 MGADGASSVHWFRKGLRLHDNPALLAAV----RGARCVRCVYILDPWFAASSSVGINRWR 71 Query: 59 FLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERD 118 FLL SL+D+D L+ RL V G+PA +F RL ++ + R+ E D EP ERD Sbjct: 72 FLLQSLEDLDTSLRKLNS---RLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERD 128 Query: 119 ESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADA 178 +I + +E ++ V + SHTL+D +IE NG PPLTY+ F + + LP +P Sbjct: 129 AAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAV 188 Query: 179 RLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYG----DNMGF----LAKINWRGGETQA 230 + E CR+ ++ E H + YG + +GF L W+GGET+A Sbjct: 189 SSQQM-------ESCRA-EIQEN-----HDDTYGVPSLEELGFPTEGLGPAVWQGGETEA 235 Query: 231 LLLLDERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKN 290 L LD+ L E+ A+ + P ++ SP +S +LRFGCLS R FY+ + DL+K Sbjct: 236 LARLDKHL--ERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKK 293 Query: 291 VQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLL 350 V+ + T + GQL+WRE+FYT + NNP +DRMEGN IC+ IPW + N L Sbjct: 294 VKRNS-------TPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDR-NPEAL 345 Query: 351 QSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLD 410 W G+TGFP ID M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLD Sbjct: 346 AKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLD 405 Query: 411 ADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVH 470 AD+SV AG+WMW+S SAF + CPV +R DP G YI++Y+P+L P +++ Sbjct: 406 ADFSVNAGSWMWLSCSAFFQQFFHCY--CPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIY 463 Query: 471 EPWRMSAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 516 EPW Q+ +C+IGV YP I++ + + N+ MK + L Sbjct: 464 EPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQL 509 >4K0R-A nrPDB Length = 617 Score = 373 bits (958), Expect = e-104, Method: Compositional matrix adjust. Identities = 211/521 (40%), Positives = 296/521 (56%), Gaps = 40/521 (7%) Query: 5 GANVI-WFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDS 63 G N + WFR GLRLHDNPAL + D + V+I D AG+ NVG NR RFLL Sbjct: 2 GVNAVHWFRKGLRLHDNPALKECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFLLQC 58 Query: 64 LQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRS 123 L+D+D L+ RL V G+PA +F RL ++ + ++ IE D EP ERD +I+ Sbjct: 59 LEDLDANLRKLNS---RLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKK 115 Query: 124 LCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDA 183 L E ++ + ++SHTL+D +IE NGG PPLTY+ F V + P AD D Sbjct: 116 LATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKM-EPLEMPADTITSDV 174 Query: 184 TFVELDPEFCRSLKLFEQLPTPEHFNVYG----DNMGF----LAKINWRGGETQALLLLD 235 + P + +H YG + +GF L+ W GGET+AL L+ Sbjct: 175 IGKCMTPL------------SDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLE 222 Query: 236 ERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRA 295 L E+ A+ F P ++ SP +S +LRFGCLS R FY+ + DL+K V+ + Sbjct: 223 RHL--ERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNS 280 Query: 296 CVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRL 355 + + GQL+WRE+FYT + NNP +D+MEGN IC+ IPW K N L W Sbjct: 281 -------SPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDK-NPEALAKWAE 332 Query: 356 GQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSV 415 G+TGFP ID M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDADWS+ Sbjct: 333 GRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSI 392 Query: 416 CAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRM 475 AG+WMW+S S+F + CPV +R DP+G YI++Y+P L P +++++PW Sbjct: 393 NAGSWMWLSCSSFFQQFFH--CYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNA 450 Query: 476 SAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 516 Q+ +CLIGV+YP+ +++ + A + N+ MK + L Sbjct: 451 PEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQL 491 >3FY4-A nrPDB Length = 537 Score = 335 bits (858), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 188/533 (35%), Positives = 290/533 (54%), Gaps = 47/533 (8%) Query: 1 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGE---------SAGTKN 51 MAT ++IWFR GLR+HDNPAL A + + PVF+ D S G+ Sbjct: 1 MATGSGSLIWFRKGLRVHDNPALEYASKGSE---FMYPVFVIDPHYMESDPSAFSPGSSR 57 Query: 52 VGYNRMRFLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCE 111 G NR+RFLL+SL+D+D L+ RLLVF+GEP + R ++ ++ R+C E D + Sbjct: 58 AGVNRIRFLLESLKDLDSSLKKLG---SRLLVFKGEPGEVLVRCLQEWKVKRLCFEYDTD 114 Query: 112 PIWNERDESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLP 171 P + D ++ ++ VSHTL++P +IE NGG PPL+YQ FL ++ G P Sbjct: 115 PYYQALDVKVKDYASSTGVEVFSPVSHTLFNPAHIIEKNGGKPPLSYQSFL---KVAGEP 171 Query: 172 PRPTADARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINW---RGGET 228 ++ + ++ L P ++P+ E D +W RGGE+ Sbjct: 172 SCAKSELVM---SYSSLPPIGDIGNLGISEVPSLEELGYKDDEQA-----DWTPFRGGES 223 Query: 229 QALLLLDERLKVEQHAFERGFYLPNQALPNIHDSPKS--MSAHLRFGCLSVRRFYWSVHD 286 +AL L + + A+ F P + P+ P + MS +L+FGCLS R FY + + Sbjct: 224 EALKRLTK--SISDKAWVANFEKP-KGDPSAFLKPATTVMSPYLKFGCLSSRYFYQCLQN 280 Query: 287 LFKNVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPN 346 ++K+V+ + + GQL+WRE+FYT + PN+D+M+GN IC IPW + + Sbjct: 281 IYKDVK-------KHTSPPVSLLGQLLWREFFYTTAFGTPNFDKMKGNRICKQIPWNE-D 332 Query: 347 ENLLQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLK 406 +L +WR G+TG+P ID M QLL GW+HH R+ VA FLTRG L+ WE G F + Sbjct: 333 HAMLAAWRDGKTGYPWIDAIMVQLLKWGWMHHLARHCVACFLTRGDLFIHWEQGRDVFER 392 Query: 407 YLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPK 466 L+D+DW++ GNWMW+S S+F + + P++ K+ DPDG YI+ ++P L ++PK Sbjct: 393 LLIDSDWAINNGNWMWLSCSSF--FYQFNRIYSPISFGKKYDPDGKYIRHFLPVLKDMPK 450 Query: 467 EFVHEPWRMSAEQQEQYECLIGVHYPERII---DLSMAVKRNMLAMKSLRNSL 516 ++++EPW Q + C++G YP+ ++ S KR M +L + Sbjct: 451 QYIYEPWTAPLSVQTKANCIVGKDYPKPMVLHDSASKECKRKMGEAYALNKKM 503 >4U63-A nrPDB Length = 498 Score = 162 bits (410), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 135/514 (26%), Positives = 233/514 (45%), Gaps = 50/514 (9%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDI 67 ++WFR LRL DN ALLAA+ + G +IPV+I + +SAG +G + +L SL + Sbjct: 28 IVWFRKDLRLSDNLALLAAV---EHGGPVIPVYIRE-KSAGP--LGGAQEWWLHHSLAAL 81 Query: 68 DDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRE 127 L+ A GRL++ G+ I R L + + + +P D++++ R+ Sbjct: 82 SSSLEKAG---GRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRD 138 Query: 128 LNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATFVE 187 + L +P ++T G P Y F ++ P P + A V Sbjct: 139 DGLTVRSFSGQLLHEPSR-LQTKSGGPYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVW 197 Query: 188 LDPEFCRSLKLFEQLPT-PEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAFE 246 E + KL LPT P+ + D W GET AL LD+ + +E Sbjct: 198 PKSEKLSNWKL---LPTKPDWAKDFSDI--------WTPGETGALDKLDDFIDGALKGYE 246 Query: 247 RGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGGA 306 G P + ++ +S HL G +S + + L +++ R Sbjct: 247 EGRDFPAKPATSL------LSPHLAAGEISPAAVWHATKGLSRHIASNDISR-------- 292 Query: 307 HITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLIDGA 366 +++WRE+ Y + + P ND + W + +E ++W G TG+P++D Sbjct: 293 -FRKEIVWREFCYHLLFHFPELGEKNWNDSFDAFSW-RDDEKSFKAWTRGMTGYPIVDAG 350 Query: 367 MRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSS 426 MRQL G +H+ +R VA+FL + L W G + F L+DAD + A NW WV+ S Sbjct: 351 MRQLWQHGTMHNRVRMIVASFLIKH-LLIDWRKGEKWFRDTLVDADPASNAANWQWVAGS 409 Query: 427 A-----FERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQE 481 F R+ + P+ ++ D DG Y++++VPEL + ++++H+P+ + + Sbjct: 410 GADASPFFRIFN------PILQGEKFDGDGDYVRRFVPELEKLERKYIHKPFEAPKDALK 463 Query: 482 QYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNS 515 + +G YP I+D A +R + A +++ + Sbjct: 464 KAGVELGKTYPLPIVDHGKARERALAAYAAVKKT 497 >1OWP-A nrPDB Length = 484 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 132/468 (28%), Positives = 214/468 (45%), Gaps = 41/468 (8%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDI 67 + W R LRL DN L AA A Q LI +F D + + ++ R+ +L LQ++ Sbjct: 6 LFWHRRDLRLSDNIGLAAARAQSAQ---LIGLFCLDPQILQSADMAPARVAYLQGCLQEL 62 Query: 68 DDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRE 127 + Q A RLL+ +G+P ++ +L +Q++ + QD EP +RD + + + Sbjct: 63 QQRYQQAG---SRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKT 119 Query: 128 LNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATFVE 187 I V+ L P ++ +G P Y F Q P+PT A + V+ Sbjct: 120 AGIRAVQLWDQLLHSPDQILSGSGN-PYSVYGPFWKNWQA---QPKPTPVATPTE--LVD 173 Query: 188 LDPEFCRSLK--LFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAF 245 L PE ++ L +LPT + D GF + GET A+ L E + Sbjct: 174 LSPEQLTAIAPLLLSELPTLKQLGFDWDG-GFPVE----PGETAAIARLQEFCDRAIADY 228 Query: 246 ERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHD---LFKNVQLRACVRGVQM 302 + P +A +S L+FG + +R+ + + L ++ + R +R Q Sbjct: 229 DPQRNFPAEA------GTSGLSPALKFGAIGIRQAWQAASAAHALSRSDEARNSIRVWQQ 282 Query: 303 TGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPL 362 +L WRE++ + P+ + PW E L +W QTG+P+ Sbjct: 283 --------ELAWREFYQHALYHFPSLADGPYRSLWQQFPWEN-REALFTAWTQAQTGYPI 333 Query: 363 IDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMW 422 +D AMRQL GW+H+ R VA+FLT+ L W G Q F+++L+D D + G W W Sbjct: 334 VDAAMRQLTETGWMHNRCRMIVASFLTK-DLIIDWRRGEQFFMQHLVDGDLAANNGGWQW 392 Query: 423 VSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNV-PKEFV 469 +SS + + P + AK+ D TYIK+++PEL +V PK+ + Sbjct: 393 SASSGMDP--KPLRIFNPASQAKKFDATATYIKRWLPELRHVHPKDLI 438 >2E0I-A nrPDB Length = 440 Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 125/478 (26%), Positives = 210/478 (43%), Gaps = 85/478 (17%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNR---MRFLLDSL 64 + FR LRL DN L AL++ D+ +IPVFI D N Y + F+++SL Sbjct: 4 IFIFRRDLRLEDNTGLNYALSECDR---VIPVFIADPRQ--LINNPYKSEFAVSFMINSL 58 Query: 65 QDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSL 124 ++DD+L+ RL VF GE + R +V I + +D P RDE IR + Sbjct: 59 LELDDELRKKG---SRLNVFFGEAEKVVSRFFNKV--DAIYVNEDYTPFSISRDEKIRKV 113 Query: 125 CRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDAT 184 C E I+F + L L N + F + V + + T + D T Sbjct: 114 CEENGIEFKAYEDYLLTPKSLFHHRN-------FTSFYNEVSKVKVREPETMEGSF-DVT 165 Query: 185 FVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHA 244 ++ +F L F+++ +P +RGG + L LL + + Sbjct: 166 DSSMNVDF---LLTFKKIESPL----------------FRGGRREGLYLLHRNVDFRRRD 206 Query: 245 FERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTG 304 + ++ +S HL+FG +S+R Y++ G Sbjct: 207 YP------------AENNNYRLSPHLKFGTISMREAYYT------------------QKG 236 Query: 305 GAHITGQLIWREYFYTMSVNNPN-----YDRMEGNDICLSIPWAKPNENLLQSWRLGQTG 359 +L WR++F ++ NP+ Y R N I W NE+ ++W+ G+TG Sbjct: 237 KEEFVRELYWRDFFTLLAYYNPHVFGHCYRREYDN-----ISWEN-NESYFEAWKEGRTG 290 Query: 360 FPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGN 419 +P+ID MR L + G+++ +R VA FL + L+ W G ++F L+D D ++ GN Sbjct: 291 YPIIDAGMRMLNSTGYINGRVRMLVAFFLVK-VLFVDWRWGERYFATKLVDYDPAINNGN 349 Query: 420 WMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSA 477 W W++S+ + + V P ++ DP+ +IK++V EL +VP +H ++ Sbjct: 350 WQWIASTGVDYMFR---VFNPWKQQEKFDPEAKFIKEWVEELKDVPPSIIHSIYKTKV 404 >1NP7-A nrPDB Length = 489 Score = 146 bits (369), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 136/505 (26%), Positives = 229/505 (45%), Gaps = 45/505 (8%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYN-----RMRFLLD 62 ++WFR+ LRLHD+ L AL G+A+ V+ +D + G+ R FL Sbjct: 9 LVWFRNDLRLHDHEPLHRALKS---GLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQ 65 Query: 63 SLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIR 122 S+Q++ + LQ + +LLV G P + ++ +Q+ I ++ + E + R Sbjct: 66 SVQNLAESLQKVGN---KLLVTTGLPEQVIPQIAKQINAKTIYYHRE---VTQEELDVER 119 Query: 123 SLCRELNIDFVEKVSH---TLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADAR 179 +L ++L I +E + TL P+ + + +P L + F ++ + RP A Sbjct: 120 NLVKQLTILGIEAKGYWGSTLCHPEDLPFSIQDLPDL-FTKFRKDIEKKKISIRPCFFAP 178 Query: 180 LEDATFVELDPEFCRSLKLFEQLPTPEHF-NVYGDNMGFLAKINWRGGETQALLLLDERL 238 +L P ++KL P PE F + D+ LA ++GGET L L + Sbjct: 179 ------SQLLP--SPNIKLELTAPPPEFFPQINFDHRSVLA---FQGGETAGLARLQDYF 227 Query: 239 KVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVR 298 H Y + D S L GCLS R Y V R Sbjct: 228 ---WHGDRLKDYKETRNGMVGADYSSKFSPWLALGCLSPRFIYQEVK--------RYEQE 276 Query: 299 GVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQT 358 V + +L+WR++F ++ N G + + PW + ++ + WR GQT Sbjct: 277 RVSNDSTHWLIFELLWRDFFRFVAQKYGNKLFNRGGLLNKNFPWQE-DQVRFELWRSGQT 335 Query: 359 GFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAG 418 G+PL+D MR+L G++ + R VA+FL + L W G + F L+D D G Sbjct: 336 GYPLVDANMRELNLTGFMSNRGRQNVASFLCKN-LGIDWRWGAEWFESCLIDYDVCSNWG 394 Query: 419 NWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAE 478 NW + + + D P +++ DP GTY++ ++PEL N+P + +H+PW +SA Sbjct: 395 NWNYTAGIGND-ARDFRYFNIPKQ-SQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSAT 452 Query: 479 QQEQYECLIGVHYPERIIDLSMAVK 503 +Q+Q+ +GV YP ++ +V+ Sbjct: 453 EQKQWGVQLGVDYPRPCVNFHQSVE 477 >1DNP-A nrPDB Length = 471 Score = 122 bits (306), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 124/522 (23%), Positives = 228/522 (43%), Gaps = 69/522 (13%) Query: 7 NVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQD 66 +++WFR LRLHDN AL AA ++ ++ ++I T N+ + + L Sbjct: 3 HLVWFRQDLRLHDNLALAAAC--RNSSARVLALYIATPRQWATHNMSPRQAELINAQL-- 58 Query: 67 IDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCR 126 + LQ A +G L+F ++ E V+ ++C E ++ + R Sbjct: 59 --NGLQIALAEKGIPLLFREVDDFVASV--EIVK--QVCAENSVTHLFYNYQYEVNERAR 112 Query: 127 ELNID-FVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATF 185 ++ ++ + V +D +++ PP H + + P + RL + Sbjct: 113 DVEVERALRNVVCEGFDDSVIL------PPGAVMTGNHEMYKVFTPFKNAWLKRLREGMP 166 Query: 186 VELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINW-RGGETQALLLLDERLKVEQ-H 243 + RS E P+ +N+ R A ++E+ + Q Sbjct: 167 ECVAAPKVRSSGSIEPSPS--------------ITLNYPRQSFDTAHFPVEEKAAIAQLR 212 Query: 244 AFER---GFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGV 300 F + G Y + P + + + +SA L G LS R+ +H L Q +A G Sbjct: 213 QFCQNGAGEYEQQRDFPAVEGTSR-LSASLATGGLSPRQ---CLHRLLAE-QPQALDGG- 266 Query: 301 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWA--------KPNENLLQS 352 G+ +LIWRE++ + +P+ +C P+ + N LQ+ Sbjct: 267 ---AGSVWLNELIWREFYRHLITYHPS--------LCKHRPFIAWTDRVQWQSNPAHLQA 315 Query: 353 WRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDAD 412 W+ G+TG+P++D AMRQL + GW+H+ LR A+FL + L W G ++F+ L+D D Sbjct: 316 WQEGKTGYPIVDAAMRQLNSTGWMHNRLRMITASFLVK-DLLIDWREGERYFMSQLIDGD 374 Query: 413 WSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEP 472 + G W W +S+ + + P ++ D +G +I+Q++PEL +VP + VHEP Sbjct: 375 LAANNGGWQWAASTGTDAAPYFRIFN-PTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEP 433 Query: 473 WRMSAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRN 514 W+ + + + + YP+ I++ A + + A ++ R Sbjct: 434 WKWAQ------KAGVTLDYPQPIVEHKEARVQTLAAYEAARK 469 >1U3C-A nrPDB Length = 509 Score = 111 bits (278), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 129/519 (24%), Positives = 217/519 (41%), Gaps = 56/519 (10%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDI 67 ++WFR LR+ DNPAL AA+ + +I +F++ E G + G +L +SL Sbjct: 15 IVWFRRDLRVEDNPALAAAV----RAGPVIALFVWAPEEEGHYHPGRVSRWWLKNSLA-- 68 Query: 68 DDQLQAATDGRGRLLVFEGEPAYIFRRLH--EQVRLHRICIEQDCEPIWNERDESIRSLC 125 QL ++ G L+ + + L + +I +P+ RD + + Sbjct: 69 --QLDSSLRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVL 126 Query: 126 RELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATF 185 I + L++P V + G P + F + + +P P + L Sbjct: 127 TAQGIAVRSFNADLLYEPWEVTDELGR-PFSMFAAFWE--RCLSMPYDPESPL-LPPKKI 182 Query: 186 VELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAF 245 + D C + L + + + N LA+ W G + D+ L F Sbjct: 183 ISGDVSKCVADPLVFEDDSEKGSN------ALLARA-WSPGWSNG----DKALTT----F 227 Query: 246 ERGFYLPNQALPNIHDSPKS--MSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMT 303 G L DS + +S HL FG +SVR+ +F V+++ + Sbjct: 228 INGPLLEYSKNRRKADSATTSFLSPHLHFGEVSVRK-------VFHLVRIKQVAWANEGN 280 Query: 304 GGAHITGQLIW-----REYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQT 358 + L REY +S N+P PWA +EN ++WR G+T Sbjct: 281 EAGEESVNLFLKSIGLREYSRYISFNHPYSHERPLLGHLKFFPWAV-DENYFKAWRQGRT 339 Query: 359 GFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAG 418 G+PL+D MR+L A GWLH +R V++F + L W G+++F LLDAD A Sbjct: 340 GYPLVDAGMRELWATGWLHDRIRVVVSSFFVK-VLQLPWRWGMKYFWDTLLDADLESDAL 398 Query: 419 NWMWVS-----SSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPW 473 W +++ S F+R + P + DP+G Y+++++PEL +P +++H PW Sbjct: 399 GWQYITGTLPDSREFDR------IDNPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPW 452 Query: 474 RMSAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSL 512 + +G +YP I+ L A R A+ + Sbjct: 453 NAPESVLQAAGIELGSNYPLPIVGLDEAKARLHEALSQM 491 >2VTB-B nrPDB Length = 525 Score = 101 bits (252), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 127/492 (25%), Positives = 205/492 (41%), Gaps = 66/492 (13%) Query: 4 RGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKN------VGYNRM 57 +G ++WFR+ LR+ DN AL A + D ++PV+ D T + G R Sbjct: 40 KGVTILWFRNDLRVLDNDALYKAWSSSD---TILPVYCLDPRLFHTTHFFNFPKTGALRG 96 Query: 58 RFLLDSLQDIDDQLQAATDGRG-RLLVFEGEPAYIFRRLHEQ-----VRLHR-ICIEQ-D 109 FL++ L D+ L RG LL+ G+P I L + V H+ C E+ D Sbjct: 97 GFLMECLVDLRKNLMK----RGLNLLIRSGKPEEILPSLAKDFGARTVFAHKETCSEEVD 152 Query: 110 CEPIWNERDESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIG 169 E + N+ + + + + L + + + H P V + P Y F +V+ Sbjct: 153 VERLVNQGLKRVGNSTK-LELIWGSTMYHKDDLPFDVFDL-----PDVYTQFRKSVE--- 203 Query: 170 LPPRPTADARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQ 229 A + +T + L S+ + +PT E V + + + GGE+ Sbjct: 204 ------AKCSIRSSTRIPLSLGPTPSVDDWGDVPTLEKLGV--EPQEVTRGMRFVGGESA 255 Query: 230 ALLLLDER------LKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWS 283 + + E LKV + G P D S L FGC+S R Y Sbjct: 256 GVGRVFEYFWKKDLLKVYKET-RNGMLGP--------DYSTKFSPWLAFGCISPRFIYEE 306 Query: 284 VHDLFKNVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWA 343 V K V + +LIWR+YF +S+ N G ++ W+ Sbjct: 307 VQRYEKER--------VANNSTYWVLFELIWRDYFRFLSIKCGNSLFHLGGPRNVNGKWS 358 Query: 344 KPNENLLQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQH 403 + ++ L +SWR +TG+PLID M++L G++ + R V +FL R + W G + Sbjct: 359 Q-DQKLFESWRDAKTGYPLIDANMKELSTTGFMSNRGRQIVCSFLVR-DMGLDWRMGAEW 416 Query: 404 FLKYLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMN 463 F LLD D GNW + + R + + P A+ DP+G Y+ ++ +L Sbjct: 417 FETCLLDYDPCSNYGNWTYGAGVNDPR--EDRYFSIP-KQAQNYDPEGEYVAFWLQQLRR 473 Query: 464 VPKEFVHEPWRM 475 +PKE H P R+ Sbjct: 474 LPKEKRHWPGRL 485 >2J08-A nrPDB Length = 420 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/212 (29%), Positives = 98/212 (46%), Gaps = 31/212 (14%) Query: 266 MSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNN 325 +S + G LS R W A RG + G +L+WR++ Y + + Sbjct: 212 LSPYFALGVLSPRLAAWE-----------AERRGGE--GARKWVAELLWRDFSYHLLYHF 258 Query: 326 PNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVA 385 P + + PW + +E L Q+W G+TG PL+D AMR+L A G+L + R A Sbjct: 259 PWMAERPLDPRFQAFPWQE-DEALFQAWYEGKTGVPLVDAAMRELHATGFLSNRARMNAA 317 Query: 386 TFLTRGGL--WQSWEHGLQHFLKYLLDADWSVCAGNWMW-----VSSSAFERLLDSSLVT 438 F + L W+ E +H LLD D +V W W V ++ + R+ + Sbjct: 318 QFAVKHLLLPWKRCEEAFRHL---LLDGDRAVNLQGWQWAGGLGVDAAPYFRVFN----- 369 Query: 439 CPVALAKRLDPDGTYIKQYVPELMN-VPKEFV 469 PV +R DP+G ++K++ PE + PK+ V Sbjct: 370 -PVLQGERHDPEGRWLKRWAPEYPSYAPKDPV 400 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 10/119 (8%) Query: 5 GANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSL 64 G ++W R LRLHD+PALL ALA ++ + + D + T R + L+++ Sbjct: 2 GPLLVWHRGDLRLHDHPALLEALARG----PVVGLVVLDPNNLKTTP---RRRAWFLENV 54 Query: 65 QDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRS 123 + + + +A G L V EG P +++ + P RD +R Sbjct: 55 RALREAYRARG---GALWVLEGLPWEKVPEAARRLKAKAVYALTSHTPYGRYRDGRVRE 110 >5O8D-A nrPDB Length = 484 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 28/129 (21%) Query: 265 SMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVN 324 ++S +L FG +S +R V N + A + LIW+E Sbjct: 286 NLSPYLHFGQISSQRVVLEVEKAESNPGSKK----------AFLDEILIWKEISDNFCYY 335 Query: 325 NPNYDRMEGNDICLSIP-WAKPNEN-----------LLQSWRLGQTGFPLIDGAMRQLLA 372 NP YD E S P WAK + N L+ + G+T PL + + +LL+ Sbjct: 336 NPGYDGFE------SFPSWAKESLNAHRNDVRSHIFTLEEFEAGKTHDPLWNASQMELLS 389 Query: 373 EGWLHHTLR 381 G +H R Sbjct: 390 TGKMHGYTR 398 >5WAB-A nrPDB Length = 751 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 316 EYFYTMSVNNPNYDRMEGNDICLSI-PWAKPNENLLQSWRLGQTGFP-LIDGAMRQLLAE 373 E ++ N N + N +S+ PWA + +L+SW LGQ G P L D ++ Sbjct: 432 ELLKAVAAENKNIVVVLSNGSVVSVAPWAGNAKGILESWLLGQAGGPALADVIFGKVSPS 491 Query: 374 GWLHHTL 380 G L T+ Sbjct: 492 GKLAQTI 498 >4ADI-A nrPDB Length = 473 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 34/96 (35%), Gaps = 13/96 (13%) Query: 388 LTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCP------- 440 + GG + W+ + D S C G WV ++ R+ + + C Sbjct: 32 IVDGGCFAPWDLEATGACICEIPTDVS-CEGLGAWVPTAPCARIWNGTQRACTFWAVNAY 90 Query: 441 -----VALAKRLDPDGTYIKQYVPELMNVPKEFVHE 471 LA +P G+Y KQY P V F H Sbjct: 91 SSGGYAQLASYFNPGGSYYKQYHPTACEVEPAFGHS 126 >5H12-A nrPDB Length = 775 Score = 28.5 bits (62), Expect = 7.7, Method: Compositional matrix adjust. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 21/97 (21%) Query: 181 EDATFVELDPEFCRSLKLFEQLPTPEH-FNVYGDNMGFLAKINWRG-------------- 225 E + E+ PE L ++EQ+ P H + G ++ ++ RG Sbjct: 649 EKLSKYEIPPE---KLVIYEQITRPLHEYKAIGPHVAVAKRLAARGVKVRPGMVIGYIVL 705 Query: 226 ---GETQALLLLDERLKVEQHAFERGFYLPNQALPNI 259 G +L E + +H ++ +Y+ NQ LP + Sbjct: 706 RGDGPISKRAILAEEFDLRKHKYDAEYYIENQVLPAV 742 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4JZY-A nrPDB 769 0.0 4K0R-A nrPDB 612 e-175 4I6J-A nrPDB 598 e-171 3FY4-A nrPDB 568 e-162 4U63-A nrPDB 510 e-145 1NP7-A nrPDB 494 e-140 1U3C-A nrPDB 449 e-126 1OWP-A nrPDB 445 e-125 2VTB-B nrPDB 439 e-123 1DNP-A nrPDB 437 e-123 2E0I-A nrPDB 411 e-115 2J08-A nrPDB 277 1e-74 Sequences not found previously or not previously below threshold: 5O8D-A nrPDB 100 1e-21 3UMV-A nrPDB 64 2e-10 1DE6-A nrPDB 33 0.30 4OO1-C nrPDB 33 0.46 6D97-A nrPDB 33 0.48 2DPN-A nrPDB 32 0.76 3SLH-A nrPDB 31 1.1 6FU3-A nrPDB 31 1.1 5DWD-A nrPDB 31 1.2 6HIV-Cd nrPDB 31 1.6 3QR1-A nrPDB 31 1.6 >4JZY-A nrPDB Length = 536 Score = 769 bits (1984), Expect = 0.0, Method: Composition-based stats. Identities = 535/540 (99%), Positives = 535/540 (99%), Gaps = 5/540 (0%) Query: 1 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL 60 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL Sbjct: 2 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL 61 Query: 61 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES 120 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES Sbjct: 62 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES 121 Query: 121 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL 180 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL Sbjct: 122 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL 181 Query: 181 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV 240 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV Sbjct: 182 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV 241 Query: 241 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGV 300 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQL GV Sbjct: 242 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQL-----GV 296 Query: 301 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 360 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF Sbjct: 297 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 356 Query: 361 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 420 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW Sbjct: 357 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 416 Query: 421 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 480 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ Sbjct: 417 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 476 Query: 481 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADV 540 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADV Sbjct: 477 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADV 536 >4K0R-A nrPDB Length = 617 Score = 612 bits (1577), Expect = e-175, Method: Composition-based stats. Identities = 208/516 (40%), Positives = 293/516 (56%), Gaps = 25/516 (4%) Query: 1 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFL 60 M + WFR GLRLHDNPAL + D + V+I D AG+ NVG NR RFL Sbjct: 1 MGVNAVH--WFRKGLRLHDNPALKECIQGAD---TIRCVYILDPWFAGSSNVGINRWRFL 55 Query: 61 LDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDES 120 L L+D+D L+ RL V G+PA +F RL ++ + ++ IE D EP ERD + Sbjct: 56 LQCLEDLDANLRKLN---SRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAA 112 Query: 121 IRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARL 180 I+ L E ++ + ++SHTL+D +IE NGG PPLTY+ F V + P AD Sbjct: 113 IKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKM-EPLEMPADTIT 171 Query: 181 EDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKV 240 D + P + + +P+ E D L+ W GGET+AL L+ L Sbjct: 172 SDVIGKCMTPLSDDHDEKYG-VPSLEELGFDTDG---LSSAVWPGGETEALTRLERHL-- 225 Query: 241 EQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGV 300 E+ A+ F P ++ SP +S +LRFGCLS R FY+ + DL+K V+ + Sbjct: 226 ERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNS----- 280 Query: 301 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 360 + + GQL+WRE+FYT + NNP +D+MEGN IC+ IPW K N L W G+TGF Sbjct: 281 --SPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDK-NPEALAKWAEGRTGF 337 Query: 361 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 420 P ID M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDADWS+ AG+W Sbjct: 338 PWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSW 397 Query: 421 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 480 MW+S S+F + CPV +R DP+G YI++Y+P L P +++++PW Q Sbjct: 398 MWLSCSSFFQQFFHCY--CPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQ 455 Query: 481 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 516 + +CLIGV+YP+ +++ + A + N+ MK + L Sbjct: 456 KVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQL 491 >4I6J-A nrPDB Length = 544 Score = 598 bits (1541), Expect = e-171, Method: Composition-based stats. Identities = 209/517 (40%), Positives = 292/517 (56%), Gaps = 24/517 (4%) Query: 1 MATRGANVI-WFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRF 59 M GA+ + WFR GLRLHDNPALLAA+ + V+I D A + +VG NR RF Sbjct: 16 MGADGASSVHWFRKGLRLHDNPALLAAVRG---ARCVRCVYILDPWFAASSSVGINRWRF 72 Query: 60 LLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDE 119 LL SL+D+D L+ RL V G+PA +F RL ++ + R+ E D EP ERD Sbjct: 73 LLQSLEDLDTSLRKLN---SRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDA 129 Query: 120 SIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADAR 179 +I + +E ++ V + SHTL+D +IE NG PPLTY+ F + + LP +P Sbjct: 130 AIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVS 189 Query: 180 LEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLK 239 + E + +P+ E + +G W+GGET+AL LD+ L Sbjct: 190 SQQM--ESCRAEIQENHDDTYGVPSLEELGFPTEGLG---PAVWQGGETEALARLDKHL- 243 Query: 240 VEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRG 299 E+ A+ + P ++ SP +S +LRFGCLS R FY+ + DL+K V+ + Sbjct: 244 -ERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNS---- 298 Query: 300 VQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTG 359 T + GQL+WRE+FYT + NNP +DRMEGN IC+ IPW + N L W G+TG Sbjct: 299 ---TPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDR-NPEALAKWAEGKTG 354 Query: 360 FPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGN 419 FP ID M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDAD+SV AG+ Sbjct: 355 FPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGS 414 Query: 420 WMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQ 479 WMW+S SAF + CPV +R DP G YI++Y+P+L P +++EPW Sbjct: 415 WMWLSCSAFFQQFFHCY--CPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESV 472 Query: 480 QEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 516 Q+ +C+IGV YP I++ + + N+ MK + L Sbjct: 473 QKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQL 509 >3FY4-A nrPDB Length = 537 Score = 568 bits (1464), Expect = e-162, Method: Composition-based stats. Identities = 187/530 (35%), Positives = 288/530 (54%), Gaps = 41/530 (7%) Query: 1 MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGE---------SAGTKN 51 MAT ++IWFR GLR+HDNPAL A + + PVF+ D S G+ Sbjct: 1 MATGSGSLIWFRKGLRVHDNPALEYASKGSE---FMYPVFVIDPHYMESDPSAFSPGSSR 57 Query: 52 VGYNRMRFLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCE 111 G NR+RFLL+SL+D+D L+ RLLVF+GEP + R ++ ++ R+C E D + Sbjct: 58 AGVNRIRFLLESLKDLDSSLKKLG---SRLLVFKGEPGEVLVRCLQEWKVKRLCFEYDTD 114 Query: 112 PIWNERDESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLP 171 P + D ++ ++ VSHTL++P +IE NGG PPL+YQ FL + G P Sbjct: 115 PYYQALDVKVKDYASSTGVEVFSPVSHTLFNPAHIIEKNGGKPPLSYQSFLK---VAGEP 171 Query: 172 PRPTADARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQAL 231 ++ + ++ L P ++P+ E D +RGGE++AL Sbjct: 172 SCAKSELVM---SYSSLPPIGDIGNLGISEVPSLEELGYKDDEQADWTP--FRGGESEAL 226 Query: 232 LLLDERLKVEQHAFERGFYLPNQALPNIHDSPKS--MSAHLRFGCLSVRRFYWSVHDLFK 289 L + + A+ F P + P+ P + MS +L+FGCLS R FY + +++K Sbjct: 227 KRLTK--SISDKAWVANFEKP-KGDPSAFLKPATTVMSPYLKFGCLSSRYFYQCLQNIYK 283 Query: 290 NVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENL 349 +V+ + + GQL+WRE+FYT + PN+D+M+GN IC IPW + + + Sbjct: 284 DVKK-------HTSPPVSLLGQLLWREFFYTTAFGTPNFDKMKGNRICKQIPWNE-DHAM 335 Query: 350 LQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLL 409 L +WR G+TG+P ID M QLL GW+HH R+ VA FLTRG L+ WE G F + L+ Sbjct: 336 LAAWRDGKTGYPWIDAIMVQLLKWGWMHHLARHCVACFLTRGDLFIHWEQGRDVFERLLI 395 Query: 410 DADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFV 469 D+DW++ GNWMW+S S+F + + P++ K+ DPDG YI+ ++P L ++PK+++ Sbjct: 396 DSDWAINNGNWMWLSCSSFFYQFN--RIYSPISFGKKYDPDGKYIRHFLPVLKDMPKQYI 453 Query: 470 HEPWRMSAEQQEQYECLIGVHYPERIIDL---SMAVKRNMLAMKSLRNSL 516 +EPW Q + C++G YP+ ++ S KR M +L + Sbjct: 454 YEPWTAPLSVQTKANCIVGKDYPKPMVLHDSASKECKRKMGEAYALNKKM 503 >4U63-A nrPDB Length = 498 Score = 510 bits (1312), Expect = e-145, Method: Composition-based stats. Identities = 130/508 (25%), Positives = 228/508 (44%), Gaps = 38/508 (7%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDI 67 ++WFR LRL DN ALLAA+ + G +IPV+I + +SAG +G + +L SL + Sbjct: 28 IVWFRKDLRLSDNLALLAAV---EHGGPVIPVYIRE-KSAGP--LGGAQEWWLHHSLAAL 81 Query: 68 DDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRE 127 L+ A GRL++ G+ I R L + + + +P D++++ R+ Sbjct: 82 SSSLEKAG---GRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRD 138 Query: 128 LNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATFVE 187 + L +P ++T G P Y F ++ P P + A V Sbjct: 139 DGLTVRSFSGQLLHEPSR-LQTKSGGPYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVW 197 Query: 188 LDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAFER 247 E + KL P + + D W GET AL LD+ + +E Sbjct: 198 PKSEKLSNWKLLPTKP--DWAKDFSDI--------WTPGETGALDKLDDFIDGALKGYEE 247 Query: 248 GFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGGAH 307 G P + ++ +S HL G +S + + L +++ R Sbjct: 248 GRDFPAKPATSL------LSPHLAAGEISPAAVWHATKGLSRHIASNDISR--------- 292 Query: 308 ITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLIDGAM 367 +++WRE+ Y + + P ND + W + +E ++W G TG+P++D M Sbjct: 293 FRKEIVWREFCYHLLFHFPELGEKNWNDSFDAFSW-RDDEKSFKAWTRGMTGYPIVDAGM 351 Query: 368 RQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSA 427 RQL G +H+ +R VA+FL + L W G + F L+DAD + A NW WV+ S Sbjct: 352 RQLWQHGTMHNRVRMIVASFLIKH-LLIDWRKGEKWFRDTLVDADPASNAANWQWVAGSG 410 Query: 428 FERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQYECLI 487 + + P+ ++ D DG Y++++VPEL + ++++H+P+ + ++ + Sbjct: 411 ADASPFFR-IFNPILQGEKFDGDGDYVRRFVPELEKLERKYIHKPFEAPKDALKKAGVEL 469 Query: 488 GVHYPERIIDLSMAVKRNMLAMKSLRNS 515 G YP I+D A +R + A +++ + Sbjct: 470 GKTYPLPIVDHGKARERALAAYAAVKKT 497 >1NP7-A nrPDB Length = 489 Score = 494 bits (1270), Expect = e-140, Method: Composition-based stats. Identities = 132/510 (25%), Positives = 224/510 (43%), Gaps = 41/510 (8%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYN-----RMRFLLD 62 ++WFR+ LRLHD+ L AL G+A+ V+ +D + G+ R FL Sbjct: 9 LVWFRNDLRLHDHEPLHRALKS---GLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQ 65 Query: 63 SLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIR 122 S+Q++ + LQ + +LLV G P + ++ +Q+ I ++ + + ++ Sbjct: 66 SVQNLAESLQKVGN---KLLVTTGLPEQVIPQIAKQINAKTIYYHREVTQEELDVERNLV 122 Query: 123 SLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLED 182 L I+ TL P+ + + +P L + F ++ + RP A + Sbjct: 123 KQLTILGIEAKGYWGSTLCHPEDLPFSIQDLPDL-FTKFRKDIEKKKISIRPCFFAPSQ- 180 Query: 183 ATFVELDPEFCRSLKLFEQLPTPEHF-NVYGDNMGFLAKINWRGGETQALLLLDERLKVE 241 ++KL P PE F + D+ LA ++GGET L L + Sbjct: 181 -------LLPSPNIKLELTAPPPEFFPQINFDHRSVLA---FQGGETAGLARLQDYF--- 227 Query: 242 QHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQ 301 H Y + D S L GCLS R Y V R V Sbjct: 228 WHGDRLKDYKETRNGMVGADYSSKFSPWLALGCLSPRFIYQEVK--------RYEQERVS 279 Query: 302 MTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFP 361 + +L+WR++F ++ N G + + PW + ++ + WR GQTG+P Sbjct: 280 NDSTHWLIFELLWRDFFRFVAQKYGNKLFNRGGLLNKNFPWQE-DQVRFELWRSGQTGYP 338 Query: 362 LIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWM 421 L+D MR+L G++ + R VA+FL + L W G + F L+D D GNW Sbjct: 339 LVDANMRELNLTGFMSNRGRQNVASFLCKN-LGIDWRWGAEWFESCLIDYDVCSNWGNWN 397 Query: 422 WVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQE 481 + + + D P +++ DP GTY++ ++PEL N+P + +H+PW +SA +Q+ Sbjct: 398 YTAGIGND-ARDFRYFNIP-KQSQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSATEQK 455 Query: 482 QYECLIGVHYPERIIDLSMAVK--RNMLAM 509 Q+ +GV YP ++ +V+ R + M Sbjct: 456 QWGVQLGVDYPRPCVNFHQSVEARRKIEQM 485 >1U3C-A nrPDB Length = 509 Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats. Identities = 122/516 (23%), Positives = 209/516 (40%), Gaps = 46/516 (8%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDI 67 ++WFR LR+ DNPAL AA+ + +I +F++ E G + G +L +SL + Sbjct: 15 IVWFRRDLRVEDNPALAAAV----RAGPVIALFVWAPEEEGHYHPGRVSRWWLKNSLAQL 70 Query: 68 DDQLQAATDGRGRLLVFEGEPAYIFRRLH--EQVRLHRICIEQDCEPIWNERDESIRSLC 125 D L++ G L+ + + L + +I +P+ RD + + Sbjct: 71 DSSLRSL----GTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVL 126 Query: 126 RELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATF 185 I + L++P V + G P + F + + +P P + L Sbjct: 127 TAQGIAVRSFNADLLYEPWEVTDELGR-PFSMFAAFWE--RCLSMPYDPESPL-LPPKKI 182 Query: 186 VELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAF 245 + D C + L + + + N L W G + F Sbjct: 183 ISGDVSKCVADPLVFEDDSEKGSNA-------LLARAWSPGWSNG--------DKALTTF 227 Query: 246 ERGFYLPNQALPNIHDSPKS--MSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMT 303 G L DS + +S HL FG +SVR+ +F V+++ + Sbjct: 228 INGPLLEYSKNRRKADSATTSFLSPHLHFGEVSVRK-------VFHLVRIKQVAWANEGN 280 Query: 304 GGAHITGQLIW-----REYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQT 358 + L REY +S N+P PWA +EN ++WR G+T Sbjct: 281 EAGEESVNLFLKSIGLREYSRYISFNHPYSHERPLLGHLKFFPWAV-DENYFKAWRQGRT 339 Query: 359 GFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAG 418 G+PL+D MR+L A GWLH +R V++ L W G+++F LLDAD A Sbjct: 340 GYPLVDAGMRELWATGWLHDRIRVVVSS-FFVKVLQLPWRWGMKYFWDTLLDADLESDAL 398 Query: 419 NWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAE 478 W +++ + + + P + DP+G Y+++++PEL +P +++H PW Sbjct: 399 GWQYITGT-LPDSREFDRIDNPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPWNAPES 457 Query: 479 QQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRN 514 + +G +YP I+ L A R A+ + Sbjct: 458 VLQAAGIELGSNYPLPIVGLDEAKARLHEALSQMWQ 493 >1OWP-A nrPDB Length = 484 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 135/516 (26%), Positives = 226/516 (43%), Gaps = 47/516 (9%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDI 67 + W R LRL DN L AA A Q LI +F D + + ++ R+ +L LQ++ Sbjct: 6 LFWHRRDLRLSDNIGLAAARAQSAQ---LIGLFCLDPQILQSADMAPARVAYLQGCLQEL 62 Query: 68 DDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRE 127 + Q A RLL+ +G+P ++ +L +Q++ + QD EP +RD + + + Sbjct: 63 QQRYQQAG---SRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKT 119 Query: 128 LNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATFVE 187 I V+ L P ++ +G P Y F Q P+PT A + + Sbjct: 120 AGIRAVQLWDQLLHSPDQILSGSGN-PYSVYGPFWKNWQA---QPKPTPVATPTELVDLS 175 Query: 188 LDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAFER 247 + + L +LPT + D GF + GET A+ L E ++ Sbjct: 176 PEQLTAIAPLLLSELPTLKQLGFDWDG-GFPVE----PGETAAIARLQEFCDRAIADYDP 230 Query: 248 GFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHD---LFKNVQLRACVRGVQMTG 304 P +A +S L+FG + +R+ + + L ++ + R +R Q Sbjct: 231 QRNFPAEAG------TSGLSPALKFGAIGIRQAWQAASAAHALSRSDEARNSIRVWQQ-- 282 Query: 305 GAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLID 364 +L WRE++ + P+ + PW E L +W QTG+P++D Sbjct: 283 ------ELAWREFYQHALYHFPSLADGPYRSLWQQFPWEN-REALFTAWTQAQTGYPIVD 335 Query: 365 GAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVS 424 AMRQL GW+H+ R VA+FLT+ L W G Q F+++L+D D + G W W + Sbjct: 336 AAMRQLTETGWMHNRCRMIVASFLTK-DLIIDWRRGEQFFMQHLVDGDLAANNGGWQWSA 394 Query: 425 SSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNV-PKEFVHEPWRMSAEQQEQY 483 SS + + P + AK+ D TYIK+++PEL +V PK+ + E+ Sbjct: 395 SSGMDP--KPLRIFNPASQAKKFDATATYIKRWLPELRHVHPKDLI----SGEITPIERR 448 Query: 484 ECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITP 519 YP I++ ++ K+ L+ ++ P Sbjct: 449 G------YPAPIVNHNLRQKQFKALYNQLKAAIAEP 478 >2VTB-B nrPDB Length = 525 Score = 439 bits (1129), Expect = e-123, Method: Composition-based stats. Identities = 117/485 (24%), Positives = 195/485 (40%), Gaps = 52/485 (10%) Query: 4 RGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKN------VGYNRM 57 +G ++WFR+ LR+ DN AL A + D ++PV+ D T + G R Sbjct: 40 KGVTILWFRNDLRVLDNDALYKAWSSSD---TILPVYCLDPRLFHTTHFFNFPKTGALRG 96 Query: 58 RFLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQ-------DC 110 FL++ L D+ L LL+ G+P I L + + + D Sbjct: 97 GFLMECLVDLRKNLMKRGL---NLLIRSGKPEEILPSLAKDFGARTVFAHKETCSEEVDV 153 Query: 111 EPIWNERDESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGL 170 E + N+ + + + + L + + + H P V + P Y F +V+ Sbjct: 154 ERLVNQGLKRVGNSTK-LELIWGSTMYHKDDLPFDVFDL-----PDVYTQFRKSVE---- 203 Query: 171 PPRPTADARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQA 230 A + +T + L S+ + +PT E V + + + GGE+ Sbjct: 204 -----AKCSIRSSTRIPLSLGPTPSVDDWGDVPTLEKLGV--EPQEVTRGMRFVGGESAG 256 Query: 231 LLLLDERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKN 290 + + E Y + D S L FGC+S R Y V K Sbjct: 257 VGRVFEYF---WKKDLLKVYKETRNGMLGPDYSTKFSPWLAFGCISPRFIYEEVQRYEKE 313 Query: 291 VQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLL 350 V + +LIWR+YF +S+ N G ++ W++ ++ L Sbjct: 314 --------RVANNSTYWVLFELIWRDYFRFLSIKCGNSLFHLGGPRNVNGKWSQ-DQKLF 364 Query: 351 QSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLD 410 +SWR +TG+PLID M++L G++ + R V +FL R + W G + F LLD Sbjct: 365 ESWRDAKTGYPLIDANMKELSTTGFMSNRGRQIVCSFLVR-DMGLDWRMGAEWFETCLLD 423 Query: 411 ADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVH 470 D GNW + + R + + P A+ DP+G Y+ ++ +L +PKE H Sbjct: 424 YDPCSNYGNWTYGAGVNDPR--EDRYFSIP-KQAQNYDPEGEYVAFWLQQLRRLPKEKRH 480 Query: 471 EPWRM 475 P R+ Sbjct: 481 WPGRL 485 >1DNP-A nrPDB Length = 471 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 120/514 (23%), Positives = 222/514 (43%), Gaps = 53/514 (10%) Query: 7 NVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQD 66 +++WFR LRLHDN AL AA ++ ++ ++I T N+ + + L Sbjct: 3 HLVWFRQDLRLHDNLALAAAC--RNSSARVLALYIATPRQWATHNMSPRQAELINAQL-- 58 Query: 67 IDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCR 126 + LQ A +G L+F ++ + ++C E ++ + R Sbjct: 59 --NGLQIALAEKGIPLLFREVDDFVASVEI----VKQVCAENSVTHLFYNYQYEVNERAR 112 Query: 127 ELNID-FVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATF 185 ++ ++ + V +D +++ PP H + + P + RL + Sbjct: 113 DVEVERALRNVVCEGFDDSVIL------PPGAVMTGNHEMYKVFTPFKNAWLKRLREGMP 166 Query: 186 VELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINW-RGGETQALLLLDERLKVEQ-H 243 + RS E P+ +N+ R A ++E+ + Q Sbjct: 167 ECVAAPKVRSSGSIEPSPS--------------ITLNYPRQSFDTAHFPVEEKAAIAQLR 212 Query: 244 AFER---GFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGV 300 F + G Y + P + + + +SA L G LS R +H L Q +A G Sbjct: 213 QFCQNGAGEYEQQRDFPAVEGTSR-LSASLATGGLSPR---QCLHRLLAE-QPQALDGG- 266 Query: 301 QMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGF 360 G+ +LIWRE++ + +P+ + + N LQ+W+ G+TG+ Sbjct: 267 ---AGSVWLNELIWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGY 323 Query: 361 PLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNW 420 P++D AMRQL + GW+H+ LR A+FL + L W G ++F+ L+D D + G W Sbjct: 324 PIVDAAMRQLNSTGWMHNRLRMITASFLVK-DLLIDWREGERYFMSQLIDGDLAANNGGW 382 Query: 421 MWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 480 W +S+ + + P ++ D +G +I+Q++PEL +VP + VHEPW+ + Sbjct: 383 QWAASTGTDAAPYFR-IFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQ--- 438 Query: 481 EQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRN 514 + + + YP+ I++ A + + A ++ R Sbjct: 439 ---KAGVTLDYPQPIVEHKEARVQTLAAYEAARK 469 >2E0I-A nrPDB Length = 440 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 128/513 (24%), Positives = 220/513 (42%), Gaps = 86/513 (16%) Query: 8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNR---MRFLLDSL 64 + FR LRL DN L AL++ D+ +IPVFI D N Y + F+++SL Sbjct: 4 IFIFRRDLRLEDNTGLNYALSECDR---VIPVFIADPRQL--INNPYKSEFAVSFMINSL 58 Query: 65 QDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSL 124 ++DD+L+ RL VF GE + R +V I + +D P RDE IR + Sbjct: 59 LELDDELRKKG---SRLNVFFGEAEKVVSRFFNKV--DAIYVNEDYTPFSISRDEKIRKV 113 Query: 125 CRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDAT 184 C E I+F + L L N + F + V + + T + D T Sbjct: 114 CEENGIEFKAYEDYLLTPKSLFHHRN-------FTSFYNEVSKVKVREPETMEGSF-DVT 165 Query: 185 FVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHA 244 ++ +F L F+++ +P +RGG + L LL + + Sbjct: 166 DSSMNVDF---LLTFKKIESPL----------------FRGGRREGLYLLHRNVDFRRRD 206 Query: 245 FERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTG 304 + ++ +S HL+FG +S+R Y++ G Sbjct: 207 YPA------------ENNNYRLSPHLKFGTISMREAYYT------------------QKG 236 Query: 305 GAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLID 364 +L WR++F ++ NP+ +I W NE+ ++W+ G+TG+P+ID Sbjct: 237 KEEFVRELYWRDFFTLLAYYNPHVFGHCYRREYDNISWEN-NESYFEAWKEGRTGYPIID 295 Query: 365 GAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVS 424 MR L + G+++ +R VA FL + L+ W G ++F L+D D ++ GNW W++ Sbjct: 296 AGMRMLNSTGYINGRVRMLVAFFLVK-VLFVDWRWGERYFATKLVDYDPAINNGNWQWIA 354 Query: 425 SSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQYE 484 S+ + + V P ++ DP+ +IK++V EL +VP +H ++ Sbjct: 355 STGVDYMF---RVFNPWKQQEKFDPEAKFIKEWVEELKDVPPSIIHSIYKTKVP------ 405 Query: 485 CLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLI 517 YP I++ V K+++ L+ Sbjct: 406 -----GYPSPIVNWLERVNYVKSEYKNVKAVLL 433 >2J08-A nrPDB Length = 420 Score = 277 bits (707), Expect = 1e-74, Method: Composition-based stats. Identities = 105/466 (22%), Positives = 169/466 (36%), Gaps = 68/466 (14%) Query: 5 GANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSL 64 G ++W R LRLHD+PALL ALA ++ + + D + T R + L+++ Sbjct: 2 GPLLVWHRGDLRLHDHPALLEALAR----GPVVGLVVLDPNNLKTT---PRRRAWFLENV 54 Query: 65 QDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSL 124 + + + +A G L V EG P +++ + P RD +R Sbjct: 55 RALREAYRARG---GALWVLEGLPWEKVPEAARRLKAKAVYALTSHTPYGRYRDGRVREA 111 Query: 125 CRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDAT 184 V L ++ + Y F + P P Sbjct: 112 L---------PVPLHLLPAPHLLPPDLPRAYRVYTPFSRLYRGAAPPLPPPEALP----- 157 Query: 185 FVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHA 244 PE + ++ G GE AL L L+ + Sbjct: 158 ------------------KGPEEGEIPREDPGLPLP---EPGEEAALAGLRAFLEAKLPR 196 Query: 245 FERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTG 304 + + +S + G LS R W A RG + G Sbjct: 197 YAEERDR------LDGEGGSRLSPYFALGVLSPRLAAWE-----------AERRGGE--G 237 Query: 305 GAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLID 364 +L+WR++ Y + + P + + PW + +E L Q+W G+TG PL+D Sbjct: 238 ARKWVAELLWRDFSYHLLYHFPWMAERPLDPRFQAFPWQE-DEALFQAWYEGKTGVPLVD 296 Query: 365 GAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVS 424 AMR+L A G+L + R A F + L W+ + F LLD D +V W W Sbjct: 297 AAMRELHATGFLSNRARMNAAQFAVKH-LLLPWKRCEEAFRHLLLDGDRAVNLQGWQWAG 355 Query: 425 SSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMN-VPKEFV 469 + V PV +R DP+G ++K++ PE + PK+ V Sbjct: 356 GLGVDAAPYFR-VFNPVLQGERHDPEGRWLKRWAPEYPSYAPKDPV 400 >5O8D-A nrPDB Length = 484 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 68/395 (17%), Positives = 127/395 (32%), Gaps = 49/395 (12%) Query: 4 RGANVIWFRHGLRLHDNPALLAALA-DKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLD 62 G V W R DN ALL + A K+ + ++ VF E G + F+L Sbjct: 38 DGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLTDEFL---EAGIRQYEFMLK 94 Query: 63 SLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIR 122 LQ+++ L G+P R + + D P+ +++ I Sbjct: 95 GLQELEVSLSRKKIPS---FFLRGDPGEKISRFVKDYNAGTLVT--DFSPL-RIKNQWIE 148 Query: 123 SLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLED 182 + ++I F E +H + E + + F + + + Sbjct: 149 KVISGISIPFFEVDAHNVVPCW---EASQKHEYAAHT-FRPKLYALLP----EFLEEFPE 200 Query: 183 ATFVELDPEFCRSLKLFEQLPTPEHFNVYG---------DNMGFLAKINWRGGETQALLL 233 + PE + E L V + ++ GE A + Sbjct: 201 LEPNSVTPELSAGAGMVETLSDVLETGVKALLPERALLKNKDPLFEPWHFEPGEKAAKKV 260 Query: 234 LDERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQL 293 ++ + ++ P + + + ++S +L FG +S +R V Sbjct: 261 MESFIADRLDSYGALRNDPTKNMLS------NLSPYLHFGQISSQRVVLEVEK------- 307 Query: 294 RACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENL---- 349 + A + LIW+E NP YD E ++ Sbjct: 308 ---AESNPGSKKAFLDEILIWKEISDNFCYYNPGYDGFESFPSWAKESLNAHRNDVRSHI 364 Query: 350 --LQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRN 382 L+ + G+T PL + + +LL+ G +H R Sbjct: 365 FTLEEFEAGKTHDPLWNASQMELLSTGKMHGYTRM 399 >3UMV-A nrPDB Length = 506 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 73/475 (15%), Positives = 137/475 (28%), Gaps = 60/475 (12%) Query: 8 VIWFRHGLRLHDN-PALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQD 66 V W RL DN L AA L F R R L L+ Sbjct: 41 VYWMLRDQRLADNWALLHAAGLAAASASPLAVAFALFPRPFLLS----ARRRQLGFLLRG 96 Query: 67 IDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQD-CEPIWNERDESIRSLC 125 + A +F G PA I L +++ + + P+ D + L Sbjct: 97 LRRLAADAAARHLPFFLFTGGPAEI-PALVQRLGASTLVADFSPLRPVREALDAVVGDLR 155 Query: 126 REL-NIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDAT 184 RE + + +H + T + + F V + Sbjct: 156 REAPGVAVHQVDAHNVVPVW----TASAKMEYSAKTFRGKVSKVMDEYLVEFPELPAVVP 211 Query: 185 FVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINW-RGGETQALLLL----DERLK 239 + PE L ++ + + +I+W GE A+ L D L Sbjct: 212 WDREQPEGVDWDALIARVCS---------EAENVPEIDWCEPGEEAAIEALLGSKDGFLT 262 Query: 240 VEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRG 299 ++E P + +S +L FG +S +R +++ ++ Sbjct: 263 KRIKSYETDRNDPTKPRAL-----SGLSPYLHFGHISAQRCALEAKKC-RHLSPKSVDAF 316 Query: 300 VQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLL--QSWRLGQ 357 ++ + Y + E L A E++ + + Sbjct: 317 LEELVVRRELAD----NFCYYQPQYDSLSGAWEWARKTLMDHAADKREHIYTREQLENAK 372 Query: 358 TGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYL--------L 409 T PL + + +++ G +H +R + + L W G + L + Sbjct: 373 THDPLWNASQLEMVHHGKMHGFMRM----YWAKKIL--EWTSGPEEALSTAIYLNDKYEI 426 Query: 410 DADWSVCAGNWMWVSSSAFERLLDSSLVTCPVAL------AKRLDPDG--TYIKQ 456 D MW ++ V + ++ D D +Y+K+ Sbjct: 427 DGRDPSGYVGCMWSICGLHDQGWKERPVFGKIRYMNYAGCKRKFDVDAYISYVKR 481 >1DE6-A nrPDB Length = 426 Score = 33.3 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 10/94 (10%) Query: 382 NTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPV 441 +A+ + R L+ GL F D S+ WV + + + P Sbjct: 313 QAIASEIVRHDLFDRVHIGLDFF-------DASINRIA-AWVIGTRNMKKALLRALLEPT 364 Query: 442 ALAKRLDPDGTYIKQ--YVPELMNVPKEFVHEPW 473 A ++L+ G Y + + E ++P + V E + Sbjct: 365 AELRKLEAPGDYTARLALLEEQKSLPWQAVWEMY 398 >4OO1-C nrPDB Length = 394 Score = 32.5 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%) Query: 90 YIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRELNIDFVEKVSHTLWDPQLVIET 149 I + +V+ +D DE E N+ K S+ L+ +V+ Sbjct: 163 RILPKKALKVKAGVRSANEDGTFSVLYPDELEDDTLNETNLKMKRKWSYVLYAKIVVLSR 222 Query: 150 NGGIPPLTYQMFLHTVQIIGLP 171 G + L + ++ +Q + LP Sbjct: 223 TGPVFDLCWNSLMYALQSVKLP 244 >6D97-A nrPDB Length = 547 Score = 32.5 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 12/72 (16%) Query: 406 KYLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVP 465 + + W+ A NW W+ + L + GT IK ++ L P Sbjct: 46 QNFVQGSWTASA-NWNWI----VDPLNGDKFIKVAEVQ-------GTEIKSFMESLSKCP 93 Query: 466 KEFVHEPWRMSA 477 K +H P + Sbjct: 94 KHGLHNPLKAPE 105 >2DPN-A nrPDB Length = 495 Score = 31.8 bits (70), Expect = 0.76, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 23/63 (36%) Query: 72 QAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRELNID 131 Q T R L EG P + +R Q+ +E D IW + R + R + Sbjct: 9 QGTTSSRAILFTLEGRPVAVAKREFRQLYPKPGWVEHDPLEIWETTLWAAREVLRRAGAE 68 Query: 132 FVE 134 E Sbjct: 69 AGE 71 >3SLH-A nrPDB Length = 441 Score = 31.4 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 38/111 (34%), Gaps = 22/111 (19%) Query: 426 SAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQYEC 485 S+ +R ++ + ++D G NVP ++ R++ Sbjct: 121 SSLQRRPMKRIIDPLTLMGAKIDSTG-----------NVPPLKIYGNPRLT--------- 160 Query: 486 LIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFW 536 G+HY + + + + + + IT P R E ++ F + Sbjct: 161 --GIHYQLPMASAQVKSCLLLAGLYARGKTCITEPAPSRDHTERLLKHFHY 209 >6FU3-A nrPDB Length = 339 Score = 31.4 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 47/147 (31%), Gaps = 16/147 (10%) Query: 398 EHGLQHFLKY-LLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLD----PDGT 452 G++ F+ + V G + + + P R D + Sbjct: 189 RKGVRAFMDNGCIACHNGVNLGGTTF-QKFGLVQGPYWKFIEDPKRDKGRADVTKKTEDE 247 Query: 453 YIKQYVPELMNVPKEFVH----EPWRMSAEQQEQYECLIGVHYPER----IIDLSMAVKR 504 + + VP L NV K + + W + + +G P+ I+ A+ Sbjct: 248 FFFR-VPGLRNVAKTYPYFHNGSVWELDKAVTIMGKAQLGKDIPKEDVDNIVVFLNALSG 306 Query: 505 NMLAMKSLRNSL-ITPPPHCRPSNEEE 530 N+ L +T P +P N+ E Sbjct: 307 NVSESARTMPELPLTAPMESKPDNKLE 333 >5DWD-A nrPDB Length = 240 Score = 31.4 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 21/62 (33%), Gaps = 2/62 (3%) Query: 313 IWREYFYTMSVNNPNYDRMEGNDIC--LSIPWAKPNENLLQSWRLGQTGFPLIDGAMRQL 370 WR+ F PN + G + P + L +T P++D + L Sbjct: 63 FWRDSFPDTMFVAPNAPHVCGGNPFGYEWFPLDLERDRTLARLAGAETAHPVLDAFLADL 122 Query: 371 LA 372 A Sbjct: 123 WA 124 >6HIV-Cd nrPDB Length = 440 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 34/84 (40%), Gaps = 11/84 (13%) Query: 453 YIKQYVPELMNVPKEFVHEPWRMSAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSL 512 Y +Q++ E++++ A Q Q+EC + +RI ++ M ++L Sbjct: 61 YKRQWLESFRVNADEYIYKYNITKAAQLAQWECEMKEQEKKRI-----EARQMMDGRQAL 115 Query: 513 RNSLITPPPHCRPSNEEEVRQFFW 536 + H E RQFF+ Sbjct: 116 KKK------HLDLLREFHERQFFF 133 >3QR1-A nrPDB Length = 813 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 20/50 (40%), Gaps = 1/50 (2%) Query: 388 LTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSAFERLLDSSLV 437 L +G + WE G F + LL D W + +LLD + + Sbjct: 22 LIKGDKFLKWEEGSSSFTEILLRVDPKGYFLYWK-IEGKEDSQLLDLAYL 70 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.117 0.320 Lambda K H 0.267 0.0359 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,180,058 Number of Sequences: 36641 Number of extensions: 743471 Number of successful extensions: 1928 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 1744 Number of HSP's gapped (non-prelim): 43 length of query: 542 length of database: 10,336,785 effective HSP length: 102 effective length of query: 440 effective length of database: 6,599,403 effective search space: 2903737320 effective search space used: 2903737320 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.3 bits)