BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= O75832
(226 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
4NIK-A nrPDB 464 e-131
2DWZ-A nrPDB 446 e-126
1WG0-A nrPDB 114 3e-26
3B7B-A nrPDB 101 3e-22
5AQ9-A nrPDB 100 4e-22
6BY9-A nrPDB 100 5e-22
5JHQ-A nrPDB 100 7e-22
5AQB-A nrPDB 98 2e-21
5AQA-A nrPDB 97 6e-21
6MWQ-A nrPDB 96 1e-20
5AQ7-A nrPDB 95 3e-20
5H76-A nrPDB 94 5e-20
6FES-A nrPDB 89 1e-18
5MIO-C nrPDB 88 3e-18
5HKP-A nrPDB 87 4e-18
6AUN-A nrPDB 84 4e-17
4OT9-A nrPDB 80 7e-16
4Z68-A nrPDB 80 9e-16
5CBO-A nrPDB 78 3e-15
3EU9-A nrPDB 77 6e-15
5ET1-A nrPDB 75 2e-14
5GP7-A nrPDB 74 7e-14
3ZKJ-A nrPDB 69 2e-12
4OAU-C nrPDB 67 7e-12
1G3N-B nrPDB 65 2e-11
5D68-A nrPDB 60 1e-09
4O1O-A nrPDB 59 2e-09
5DND-A nrPDB 58 4e-09
6EMK-G nrPDB 57 6e-09
3EHQ-A nrPDB 54 5e-08
2KXP-C nrPDB 52 3e-07
5U0J-A nrPDB 49 2e-06
1BD8-A nrPDB 48 3e-06
5U0K-A nrPDB 48 3e-06
5UQE-A nrPDB 47 5e-06
3LJN-A nrPDB 47 5e-06
1BLX-B nrPDB 47 7e-06
5UIL-A nrPDB 47 9e-06
3T9K-A nrPDB 46 1e-05
6BOA-A nrPDB 44 5e-05
3UI2-A nrPDB 44 6e-05
1DCQ-A nrPDB 44 6e-05
3DEO-A nrPDB 43 9e-05
4XD0-A nrPDB 43 1e-04
6E2G-A nrPDB 40 6e-04
6DMR-A nrPDB 39 0.002
4BSZ-B nrPDB 39 0.002
2RFA-A nrPDB 39 0.003
2A5E-A nrPDB 35 0.026
5IRX-A nrPDB 33 0.074
1D9S-A nrPDB 33 0.078
4GMM-A nrPDB 33 0.13
2NYJ-A nrPDB 33 0.13
3I5Q-B nrPDB 33 0.13
3I5P-A nrPDB 32 0.15
2B0O-E nrPDB 32 0.15
3LVQ-E nrPDB 32 0.16
6DVZ-A nrPDB 32 0.21
6OO7-A nrPDB 31 0.43
6G1K-A nrPDB 30 0.84
4N5Q-A nrPDB 30 1.1
6C8G-A nrPDB 29 2.0
6BBJ-A nrPDB 28 3.5
6BO5-A nrPDB 28 3.9
5HI9-A nrPDB 28 3.9
5AN8-A nrPDB 28 3.9
2ZCI-A nrPDB 28 4.6
3W9G-A nrPDB 27 7.1
6HEG-A nrPDB 27 9.4
6MHW-A nrPDB 27 9.7
>4NIK-A nrPDB
Length = 230
Score = 464 bits (1193), Expect = e-131, Method: Compositional matrix adjust.
Identities = 226/226 (100%), Positives = 226/226 (100%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL
Sbjct: 5 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 64
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE 120
QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE
Sbjct: 65 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE 124
Query: 121 IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC 180
IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC
Sbjct: 125 IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC 184
Query: 181 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG
Sbjct: 185 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 230
>2DWZ-A nrPDB
Length = 231
Score = 446 bits (1147), Expect = e-126, Method: Compositional matrix adjust.
Identities = 213/226 (94%), Positives = 221/226 (97%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
MEGCVSN+M+CNLAYSGKL+ELKE ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL
Sbjct: 1 MEGCVSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE 120
QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALL KGA VNAVNQNGCTPLHYAASKNRHE
Sbjct: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHE 120
Query: 121 IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC 180
IAVMLLEGGANPDAKDHY+ATAMHRAAAKGNLKM+HILL+YKASTNIQDTEGNTPLHLAC
Sbjct: 121 IAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLAC 180
Query: 181 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
DEERVEEAK LV+QGASIYIENKEEKTPLQVAKGGLGLILKR+ EG
Sbjct: 181 DEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAEG 226
>1WG0-A nrPDB
Length = 243
Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 75/210 (35%), Positives = 111/210 (52%), Gaps = 8/210 (3%)
Query: 5 VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV 64
+SN + + +++E + + SL + DQD R LHW+ S EI FLL
Sbjct: 1 MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKME 60
Query: 65 PVN---DKDDAGWSPLHIAASAGRDEIVKALLGKGAQ--VNAVNQNGCTPLHYAASKNRH 119
VN DD+GW+P HIA S G E+VK+L + + +N + G T LH A K
Sbjct: 61 NVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWF 120
Query: 120 EIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILL-YYKASTNIQDTEGNTPLHL 178
E++ L+E GA+ KD + +HRAA+ G+LK+I +L K++ N QD +G TPL
Sbjct: 121 EVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFH 180
Query: 179 ACDEERVEEAKLLVSQGASIY--IENKEEK 206
A E + A LLV + + Y ++NK K
Sbjct: 181 ALAEGHGDAAVLLVEKYGAEYDLVDNKGAK 210
Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 50/152 (32%), Positives = 74/152 (48%), Gaps = 8/152 (5%)
Query: 76 PLHIAASAGRDEIVKALL-GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
PLH A V+ LL K + + +Q+G PLH++ S HEI LL N +
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64
Query: 135 KDHYE---ATAMHRAAAKGNLKMIHILL--YYKASTNIQDTEGNTPLHLACDEERVEEAK 189
D+ + T H A + GNL+++ L K N +G T LHLA ++ E ++
Sbjct: 65 DDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQ 124
Query: 190 LLVSQGASIYIENKEEKTPLQVAK--GGLGLI 219
L+ GAS+ I++K + PL A G L LI
Sbjct: 125 FLIENGASVRIKDKFNQIPLHRAASVGSLKLI 156
>3B7B-A nrPDB
Length = 237
Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
+D RT L A H E V++L++ G V+ KD G + LH+AA G E+V+ LL G
Sbjct: 42 EDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQ 101
Query: 98 -QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
VN + G TP+ +A ++ +LL G++ + +D+ E +H AA G + +
Sbjct: 102 MDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAE 161
Query: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
ILL K + + G++PLH+A E R + L +S+ + + ++NKE +TPLQ A
Sbjct: 162 ILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 217
Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 52/139 (37%), Positives = 76/139 (54%), Gaps = 1/139 (0%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
SPLH AA AG +I L+ GA ++ +++ TPL AA N E L++ GA D
Sbjct: 13 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 72
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERVEEAKLLVS 193
KD +T +H AA KG+ +++ LL + N QD G TP+ A + + V+ KLL+S
Sbjct: 73 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 132
Query: 194 QGASIYIENKEEKTPLQVA 212
+G+ I I + EE L A
Sbjct: 133 KGSDINIRDNEENICLHWA 151
Score = 63.2 bits (152), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 35/147 (23%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVNDKDDA 72
A + LE +K I A +L D + T LH A GH E+V++LL G + VN +DD
Sbjct: 52 AENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG 110
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVN-------------------------------- 100
GW+P+ A ++VK LL KG+ +N
Sbjct: 111 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 170
Query: 101 -AVNQNGCTPLHYAASKNRHEIAVMLL 126
AVN +G +PLH AA +NR++ V+ L
Sbjct: 171 HAVNIHGDSPLHIAARENRYDCVVLFL 197
Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 49/93 (52%)
Query: 103 NQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK 162
+QN +PLH AA +I ML++ GAN D + T + AA +L+ + L+
Sbjct: 8 HQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAG 67
Query: 163 ASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
A + +D EG+T LHLA + E + L+S G
Sbjct: 68 ALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG 100
>5AQ9-A nrPDB
Length = 422
Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 55/133 (41%), Positives = 80/133 (60%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ L+ GA VNA + G TPLH AA EI +LL+ GA+ DA D +
Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 80
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL A N D++G TPLHLA +E ++L+ GA +
Sbjct: 81 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVN 140
Query: 200 IENKEEKTPLQVA 212
++K KTP +A
Sbjct: 141 AQDKFGKTPFDLA 153
Score = 96.7 bits (239), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 60/145 (41%), Positives = 80/145 (55%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V L+ G VN D+ G +PLH+AA +G EIV+ LL GA V+A + G
Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 80
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA+ +A D T +H AA G L+++ +LL + A N
Sbjct: 81 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVN 140
Query: 167 IQDTEGNTPLHLACDEERVEEAKLL 191
QD G TP LA D + LL
Sbjct: 141 AQDKFGKTPFDLADDNGNDDVGTLL 165
Score = 91.7 bits (226), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 56/138 (40%), Positives = 81/138 (58%), Gaps = 1/138 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ ++A+ + D T LH A +GH EIVE LL+ G V+ D G
Sbjct: 22 ARAGQDDEVR-ILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 80
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
++PLH+AA G EIV+ LL GA VNA++ +G TPLH AA EI +LL+ GA+ +
Sbjct: 81 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVN 140
Query: 134 AKDHYEATAMHRAAAKGN 151
A+D + T A GN
Sbjct: 141 AQDKFGKTPFDLADDNGN 158
Score = 73.2 bits (178), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 47/112 (41%), Positives = 60/112 (53%), Gaps = 1/112 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
AYSG LE + E +L + +D T LH A GH EIVE LL+ G VN D G
Sbjct: 55 AYSGHLE-IVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDG 113
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
+PLH+AA G EIV+ LL GA VNA ++ G TP A ++ +L
Sbjct: 114 MTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLL 165
>6BY9-A nrPDB
Length = 328
Score = 100 bits (249), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 60/176 (34%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
+D RT L A H E V++L++ G V+ KD G + LH+AA G E+V+ LL G
Sbjct: 133 EDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQ 192
Query: 98 -QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
VN + G TP+ +A ++ +LL G++ + +D+ E +H AA G + +
Sbjct: 193 MDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAE 252
Query: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
ILL K + + G++PLH+A E R + L +S+ + + ++NKE +TPLQ A
Sbjct: 253 ILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 308
Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 99/196 (50%), Gaps = 3/196 (1%)
Query: 20 EELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK--DDAGWSPL 77
E L+ +++A S + + L+++ G + V +L G+ N K SPL
Sbjct: 47 ETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPL 106
Query: 78 HIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
H AA AG +I L+ GA ++ +++ TPL AA N E L++ GA D KD
Sbjct: 107 HAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA 166
Query: 138 YEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+T +H AA KG+ +++ LL + N QD G TP+ A + + V+ KLL+S+G+
Sbjct: 167 EGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 226
Query: 197 SIYIENKEEKTPLQVA 212
I I + EE L A
Sbjct: 227 DINIRDNEENICLHWA 242
Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 35/147 (23%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVNDKDDA 72
A + LE +K I A +L D + T LH A GH E+V++LL G + VN +DD
Sbjct: 143 AENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG 201
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVN-------------------------------- 100
GW+P+ A ++VK LL KG+ +N
Sbjct: 202 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDL 261
Query: 101 -AVNQNGCTPLHYAASKNRHEIAVMLL 126
AVN +G +PLH AA +NR++ V+ L
Sbjct: 262 HAVNIHGDSPLHIAARENRYDCVVLFL 288
>5JHQ-A nrPDB
Length = 482
Score = 100 bits (248), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 75/232 (32%), Positives = 111/232 (47%), Gaps = 33/232 (14%)
Query: 14 AYSGKLEELKESI----------LADKSLATRTDQDSR--TALHWACSAGHTEIVEFLLQ 61
A SG L EL E+ L D + D R + LH+A G ++VE LLQ
Sbjct: 11 AVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ 70
Query: 62 LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEI 121
+G V+ +DD G PLH A S G E+V LL +GA NA + TPLH AA K + ++
Sbjct: 71 MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDV 130
Query: 122 AVMLLEGGANPDAKD--------------------HYEATAMHRAAAKGN-LKMIHILLY 160
++LL+ GA+P+ ++ Y+ + AA GN K++ +L
Sbjct: 131 CIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTP 190
Query: 161 YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
+ + D +TPLHLA RV +LL+ GA ++ ++K PL A
Sbjct: 191 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNA 242
Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 68/201 (33%), Positives = 96/201 (47%), Gaps = 24/201 (11%)
Query: 36 TDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
+D T LH A IV+ LLQ G V+ KD G PLH A S G E+ + LL
Sbjct: 198 SDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH 257
Query: 96 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP--------DAKD----------- 136
GA VNA++ TPLH AASKNR E+ +LL GA+P A D
Sbjct: 258 GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 317
Query: 137 --HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC---DEERVEEAKLL 191
++ ++ +AA + +L + L + Q T LH A +R + +LL
Sbjct: 318 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELL 377
Query: 192 VSQGASIYIENKEEKTPLQVA 212
+ +GA++ +NK+ TPL VA
Sbjct: 378 LRKGANVNEKNKDFMTPLHVA 398
Score = 80.1 bits (196), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 68/223 (30%), Positives = 93/223 (41%), Gaps = 54/223 (24%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALL---------- 93
LH ACS GH E+V LL G N +D+ ++PLH AA G+ ++ LL
Sbjct: 86 LHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRN 145
Query: 94 --GKGA----------------------------------------QVNAVNQNG--CTP 109
GK A VN +G TP
Sbjct: 146 TDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTP 205
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
LH AA NR I +LL+ GA+ AKD +H A + G+ ++ +LL + A N D
Sbjct: 206 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 265
Query: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
TPLH A + RVE LL+S GA + N K+ + +A
Sbjct: 266 LWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 308
Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/163 (32%), Positives = 85/163 (52%), Gaps = 2/163 (1%)
Query: 27 LADKSL-ATRTDQDSRTALHWACSAGHTE-IVEFLLQLGVPVNDKDDAGWSPLHIAASAG 84
LAD S A T + + L A +G+ E ++ L L V + D +PLH+AA
Sbjct: 154 LADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYN 213
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMH 144
R IV+ LL GA V+A ++ G PLH A S +E+ +LL+ GA +A D ++ T +H
Sbjct: 214 RVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLH 273
Query: 145 RAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEE 187
AA+K +++ +LL + A + + G + + +A E E
Sbjct: 274 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 316
Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 34/90 (37%), Positives = 53/90 (58%)
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMH 144
R ++ + LL KGA VN N++ TPLH AA + +++ +L + GA +A D TA+H
Sbjct: 370 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 429
Query: 145 RAAAKGNLKMIHILLYYKASTNIQDTEGNT 174
RAA G+L+ +LL Y + +I +G T
Sbjct: 430 RAALAGHLQTCRLLLSYGSDPSIISLQGFT 459
Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHT---EIVEFLLQLGVPVNDKD 70
A L ++K++ LA + + + Q TALH A ++ H ++ E LL+ G VN+K+
Sbjct: 330 AREADLAKVKKT-LALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKN 388
Query: 71 DAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA 130
+PLH+AA +++++ L GA++NA++ G T LH AA + +LL G+
Sbjct: 389 KDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 448
Query: 131 NP 132
+P
Sbjct: 449 DP 450
Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 57/241 (23%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA------------SAG 84
D+ LH ACS GH E+ E LL+ G VN D ++PLH AA S G
Sbjct: 232 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 291
Query: 85 RDEIVKALLGKGA--------------------------------------QVNAVN--- 103
D + GK A + +N
Sbjct: 292 ADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQ 351
Query: 104 -QNGCTPLHYAASK---NRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILL 159
Q+ T LH A + R ++ +LL GAN + K+ T +H AA + + ++ +L
Sbjct: 352 PQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLH 411
Query: 160 YYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLI 219
+ A N DT G T LH A ++ +LL+S G+ I + + T Q+ + I
Sbjct: 412 KHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQI 471
Query: 220 L 220
L
Sbjct: 472 L 472
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 45/91 (49%)
Query: 18 KLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPL 77
K +++ E +L + ++D T LH A H +++E L + G +N D G + L
Sbjct: 369 KRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTAL 428
Query: 78 HIAASAGRDEIVKALLGKGAQVNAVNQNGCT 108
H AA AG + + LL G+ + ++ G T
Sbjct: 429 HRAALAGHLQTCRLLLSYGSDPSIISLQGFT 459
>5AQB-A nrPDB
Length = 428
Score = 98.2 bits (243), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 61/145 (42%), Positives = 82/145 (56%), Gaps = 1/145 (0%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + L+ G VN D+ GW+PLH+AA G EIV+ LL GA VNA + +G
Sbjct: 21 AARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADVNAADIDG 79
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA+ +A D T +H AA G+L+++ +LL A N
Sbjct: 80 YTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVN 139
Query: 167 IQDTEGNTPLHLACDEERVEEAKLL 191
QD G TP LA D + A++L
Sbjct: 140 AQDKFGKTPRDLAIDNGNEDIAEVL 164
Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 54/133 (40%), Positives = 79/133 (59%), Gaps = 1/133 (0%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ + L+ GA VNA+++ G TPLH AA + EI LL+ GA+ +A D
Sbjct: 21 AARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHL-EIVECLLKNGADVNAADIDG 79
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL Y A N D G TPLHLA +E ++L+ GA +
Sbjct: 80 YTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVN 139
Query: 200 IENKEEKTPLQVA 212
++K KTP +A
Sbjct: 140 AQDKFGKTPRDLA 152
Score = 87.0 bits (214), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 71/194 (36%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
D+ T LH A + GH EIVE LL+ G VN D G++PLH+AA +G EIV+ LL G
Sbjct: 44 DEVGWTPLHLA-AWGHLEIVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYG 102
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
A VNA +Q G TPLH AA EI +LL+ GA+ +A+D + T A GN +
Sbjct: 103 ADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAE 162
Query: 157 ILLYYKASTNIQDTEGNTPLHLACDE--ERVEEAKLLVSQGASIYIENKEEKTPLQVAKG 214
+L ++D A D+ RV +L ++ G + EE+ P+
Sbjct: 163 VLGKAATLVKVKD---------AADQLGARVGYIELDLNSGKILESFRSEERFPMMSTFK 213
Query: 215 GL--GLILKRMVEG 226
L G IL R+ G
Sbjct: 214 VLLAGAILSRIDAG 227
Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 50/115 (43%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Query: 11 CNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD 70
+LA G LE + E +L + + D D T LH A +GH EIVE LL+ G VN D
Sbjct: 51 LHLAAWGHLE-IVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADD 109
Query: 71 DAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
AG++PLH+AA G EIV+ LL GA VNA ++ G TP A +IA +L
Sbjct: 110 QAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVL 164
>5AQA-A nrPDB
Length = 418
Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 55/133 (41%), Positives = 79/133 (59%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ L+ GA VNA + G TPLH AA EI +LL+ GA+ DA D +
Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 80
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL A N D++G TPLHLA E ++L+ GA +
Sbjct: 81 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVD 140
Query: 200 IENKEEKTPLQVA 212
++K K PL +A
Sbjct: 141 AQDKFGKRPLWLA 153
Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 56/138 (40%), Positives = 83/138 (60%), Gaps = 1/138 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ ++A+ + D T LH A +GH EIVE LL+ G V+ D G
Sbjct: 22 ARAGQDDEVR-ILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 80
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
++PLH+AA G EIV+ LL GA VNA++ +G TPLH AA EI +LL+ GA+ D
Sbjct: 81 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVD 140
Query: 134 AKDHYEATAMHRAAAKGN 151
A+D + + AA +G+
Sbjct: 141 AQDKFGKRPLWLAADQGH 158
Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 60/147 (40%), Positives = 81/147 (55%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V L+ G VN D+ G +PLH+AA +G EIV+ LL GA V+A + G
Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 80
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA+ +A D T +H AA G +++ +LL A +
Sbjct: 81 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVD 140
Query: 167 IQDTEGNTPLHLACDEERVEEAKLLVS 193
QD G PL LA D+ E A LV+
Sbjct: 141 AQDKFGKRPLWLAADQGHAEIAAKLVA 167
Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 50/113 (44%), Positives = 63/113 (55%), Gaps = 1/113 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
AYSG LE + E +L + +D T LH A GH EIVE LL+ G VN D G
Sbjct: 55 AYSGHLE-IVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDG 113
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 126
+PLH+AA G EIV+ LL GA V+A ++ G PL AA + EIA L+
Sbjct: 114 MTPLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166
>6MWQ-A nrPDB
Length = 493
Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 52/133 (39%), Positives = 81/133 (60%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ L+ GA VNA+++ G TPLH AA + EI +LL+ GA+ +A D +
Sbjct: 12 AARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAADLWG 71
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL Y A N D G TPLHL + +E ++L+ GA +
Sbjct: 72 QTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGADVN 131
Query: 200 IENKEEKTPLQVA 212
++K KT ++
Sbjct: 132 AQDKFGKTAFDIS 144
Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 73/192 (38%), Positives = 98/192 (51%), Gaps = 5/192 (2%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ ++A+ + D+ T LH A GH EIVE LL+ G VN D G
Sbjct: 13 ARAGQDDEVR-ILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAADLWG 71
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
+PLH+AA+AG EIV+ LL GA VNA++ G TPLH A EI +LL+ GA+ +
Sbjct: 72 QTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGADVN 131
Query: 134 AKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVS 193
A+D + TA + GN + IL S LA DE AK L S
Sbjct: 132 AQDKFGKTAFDISIDNGNEDLAEILQKLNLSDIAHRIVAPGKGILAADESTGSIAKRLQS 191
Query: 194 QGASIYIENKEE 205
G EN EE
Sbjct: 192 IGT----ENTEE 199
Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 57/145 (39%), Positives = 80/145 (55%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V L+ G VN D G +PLH+AA G EIV+ LL GA VNA + G
Sbjct: 12 AARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAADLWG 71
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA+ EI +LL+ GA+ +A D T +H A G+L+++ +LL + A N
Sbjct: 72 QTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGADVN 131
Query: 167 IQDTEGNTPLHLACDEERVEEAKLL 191
QD G T ++ D + A++L
Sbjct: 132 AQDKFGKTAFDISIDNGNEDLAEIL 156
>5AQ7-A nrPDB
Length = 418
Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 60/147 (40%), Positives = 79/147 (53%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V LL G VN D+ G++PLH+AA G IV+ LL GA VNA ++ G
Sbjct: 21 AARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERG 80
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA +A D +H AA G +++ +LL A +
Sbjct: 81 HTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVD 140
Query: 167 IQDTEGNTPLHLACDEERVEEAKLLVS 193
QD G PL LA D+ E A LV+
Sbjct: 141 AQDKFGKRPLWLAADQGHAEIAAKLVA 167
Score = 87.4 bits (215), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 56/138 (40%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ +LA+ + D+ T LH A GH IVE LL+ G VN D+ G
Sbjct: 22 ARAGQDDEVR-ILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERG 80
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
+PLH+AA G EIV+ LL GA VNA + G PLH AA EI +LL+ GA+ D
Sbjct: 81 HTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVD 140
Query: 134 AKDHYEATAMHRAAAKGN 151
A+D + + AA +G+
Sbjct: 141 AQDKFGKRPLWLAADQGH 158
Score = 87.0 bits (214), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 52/133 (39%), Positives = 75/133 (56%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ LL GA VN ++ G TPLH AA + I +LL+ GA+ +A D
Sbjct: 21 AARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERG 80
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL A N D G PLHLA E ++L+ GA +
Sbjct: 81 HTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVD 140
Query: 200 IENKEEKTPLQVA 212
++K K PL +A
Sbjct: 141 AQDKFGKRPLWLA 153
Score = 70.9 bits (172), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 47/113 (41%), Positives = 62/113 (54%), Gaps = 1/113 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A+ G L + E +L + + D+ T LH A GH EIVE LL+ G VN D G
Sbjct: 55 AWEGHLG-IVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIG 113
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 126
+PLH+AA G EIV+ LL GA V+A ++ G PL AA + EIA L+
Sbjct: 114 TAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166
>5H76-A nrPDB
Length = 201
Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 59/149 (39%), Positives = 87/149 (58%), Gaps = 2/149 (1%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ ++A+ + D T LH A +GH EIVE LL+ G V+ D G
Sbjct: 14 ARAGQDDEVR-ILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 72
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
++PLH+AA G EIV+ LL GA VNA++ +G TPLH AA EI +LL+ GA +
Sbjct: 73 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VN 131
Query: 134 AKDHYEATAMHRAAAKGNLKMIHILLYYK 162
A+D + TA + GN + IL +Y+
Sbjct: 132 AQDKFGKTAFDISIDNGNEDLAQILAFYE 160
Score = 91.3 bits (225), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 53/133 (39%), Positives = 79/133 (59%), Gaps = 1/133 (0%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ L+ GA VNA + G TPLH AA EI +LL+ GA+ DA D +
Sbjct: 13 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 72
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL A N D++G TPLHLA +E ++L+ GA +
Sbjct: 73 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VN 131
Query: 200 IENKEEKTPLQVA 212
++K KT ++
Sbjct: 132 AQDKFGKTAFDIS 144
Score = 87.8 bits (216), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 57/145 (39%), Positives = 81/145 (55%), Gaps = 1/145 (0%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V L+ G VN D+ G +PLH+AA +G EIV+ LL GA V+A + G
Sbjct: 13 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFG 72
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA+ +A D T +H AA G L+++ +LL + A N
Sbjct: 73 YTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VN 131
Query: 167 IQDTEGNTPLHLACDEERVEEAKLL 191
QD G T ++ D + A++L
Sbjct: 132 AQDKFGKTAFDISIDNGNEDLAQIL 156
>6FES-A nrPDB
Length = 367
Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 56/135 (41%), Positives = 73/135 (54%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V LL G VN D+ G++PLH+AA G IV+ LL GA VNA ++ G
Sbjct: 13 AARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERG 72
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA +A D +H AA G+ +++ +LL A
Sbjct: 73 HTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGADAR 132
Query: 167 IQDTEGNTPLHLACD 181
QD G TP LA D
Sbjct: 133 AQDKFGKTPEDLARD 147
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/134 (38%), Positives = 75/134 (55%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ LL GA VN ++ G TPLH AA + I +LL+ GA+ +A D
Sbjct: 13 AARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERG 72
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
T +H AA G+L+++ +LL A N D G PLHLA E ++L+ GA
Sbjct: 73 HTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGADAR 132
Query: 200 IENKEEKTPLQVAK 213
++K KTP +A+
Sbjct: 133 AQDKFGKTPEDLAR 146
Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 53/128 (41%), Positives = 73/128 (57%), Gaps = 1/128 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ +LA+ + D+ T LH A GH IVE LL+ G VN D+ G
Sbjct: 14 ARAGQDDEVR-ILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERG 72
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
+PLH+AA G EIV+ LL GA VNA + G PLH AA EI +LL+ GA+
Sbjct: 73 HTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGADAR 132
Query: 134 AKDHYEAT 141
A+D + T
Sbjct: 133 AQDKFGKT 140
Score = 64.3 bits (155), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 37/86 (43%), Positives = 48/86 (55%)
Query: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
E +L + + D+ T LH A GH EIVE LL+ G VN D G +PLH+AA
Sbjct: 56 EVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMW 115
Query: 84 GRDEIVKALLGKGAQVNAVNQNGCTP 109
G +EIV+ LL GA A ++ G TP
Sbjct: 116 GHEEIVEVLLKNGADARAQDKFGKTP 141
Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
AY+G LE + E +L + + TD LH A GH EIVE LL+ G +D G
Sbjct: 80 AYTGHLE-IVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGADARAQDKFG 138
Query: 74 WSPLHIAASAG--------RDEIVKALL 93
+P +A G R EI++A++
Sbjct: 139 KTPEDLARDNGYESVARLARKEIIRAVV 166
>5MIO-C nrPDB
Length = 573
Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 57/145 (39%), Positives = 80/145 (55%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V L+ G VN D +G +PLH+AA+ G EIV+ LL GA V+A + G
Sbjct: 417 AARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMG 476
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
TPLH AA EI +LL+ GA+ +A D + T + AA G+LK++ LL + A N
Sbjct: 477 STPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVN 536
Query: 167 IQDTEGNTPLHLACDEERVEEAKLL 191
QD G T + D + A++L
Sbjct: 537 AQDKFGKTAYDTSIDNGSEDLAEIL 561
Score = 86.7 bits (213), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 51/128 (39%), Positives = 77/128 (60%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ L+ GA VNA + +G TPLH AA+ EI +LL+ GA+ A D
Sbjct: 417 AARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMG 476
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
+T +H AA G+L+++ +LL + A N DT G+TPL LA ++ + L+ GA +
Sbjct: 477 STPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVN 536
Query: 200 IENKEEKT 207
++K KT
Sbjct: 537 AQDKFGKT 544
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 57/145 (39%), Positives = 82/145 (56%), Gaps = 1/145 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G+ +E++ ++A+ + TD T LH A + GH EIVE LL+ G V+ D G
Sbjct: 418 ARAGQDDEVR-VLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMG 476
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
+PLH+AA G EIV+ LL GA VNAV+ G TPL AA +I LL+ GA+ +
Sbjct: 477 STPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVN 536
Query: 134 AKDHYEATAMHRAAAKGNLKMIHIL 158
A+D + TA + G+ + IL
Sbjct: 537 AQDKFGKTAYDTSIDNGSEDLAEIL 561
>5HKP-A nrPDB
Length = 351
Score = 87.4 bits (215), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 69/201 (34%), Positives = 97/201 (48%), Gaps = 24/201 (11%)
Query: 36 TDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
+D T LH A IV+ LLQ G V+ KD G PLH A S G E+ + LL
Sbjct: 54 SDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH 113
Query: 96 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP--------DAKD----------- 136
GA VNA++ TPLH AASKNR E+ +LL GA+P A D
Sbjct: 114 GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 173
Query: 137 --HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC---DEERVEEAKLL 191
++ ++ +AA + +L + L + Q T LH A +R + A+LL
Sbjct: 174 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELL 233
Query: 192 VSQGASIYIENKEEKTPLQVA 212
+ +GA++ +NK+ TPL VA
Sbjct: 234 LRKGANVNEKNKDFMTPLHVA 254
Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 53/163 (32%), Positives = 85/163 (52%), Gaps = 2/163 (1%)
Query: 27 LADKSL-ATRTDQDSRTALHWACSAGHTE-IVEFLLQLGVPVNDKDDAGWSPLHIAASAG 84
LAD S A T + + L A +G+ E ++ L L V + D +PLH+AA
Sbjct: 10 LADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYN 69
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMH 144
R IV+ LL GA V+A ++ G PLH A S +E+ +LL+ GA +A D ++ T +H
Sbjct: 70 RVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLH 129
Query: 145 RAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEE 187
AA+K +++ +LL + A + + G + + +A E E
Sbjct: 130 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 172
Score = 67.4 bits (163), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 48/134 (35%), Positives = 69/134 (51%), Gaps = 1/134 (0%)
Query: 80 AASAGRDEIVKALLGK-GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHY 138
AA +G +E + ALL +A + TPLH AA NR I +LL+ GA+ AKD
Sbjct: 31 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 90
Query: 139 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
+H A + G+ ++ +LL + A N D TPLH A + RVE LL+S GA
Sbjct: 91 GLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 150
Query: 199 YIENKEEKTPLQVA 212
+ N K+ + +A
Sbjct: 151 TLVNCHGKSAVDMA 164
Score = 60.1 bits (144), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 34/90 (37%), Positives = 53/90 (58%)
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMH 144
R ++ + LL KGA VN N++ TPLH AA + +++ +L + GA +A D TA+H
Sbjct: 226 RKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALH 285
Query: 145 RAAAKGNLKMIHILLYYKASTNIQDTEGNT 174
RAA G+L+ +LL Y + +I +G T
Sbjct: 286 RAALAGHLQTCRLLLSYGSDPSIISLQGFT 315
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 34/101 (33%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 35 RTDQDSRTALHWACSAGHT---EIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKA 91
+ Q TALH A ++ H ++ E LL+ G VN+K+ +PLH+AA +++++
Sbjct: 206 KQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEV 265
Query: 92 LLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
L GA++NA++ G T LH AA + +LL G++P
Sbjct: 266 LHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDP 306
Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 63/241 (26%), Positives = 95/241 (39%), Gaps = 57/241 (23%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA------------SAG 84
D+ LH ACS GH E+ E LL+ G VN D ++PLH AA S G
Sbjct: 88 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 147
Query: 85 RDEIVKALLGKGA--------------------------------------QVNAVN--- 103
D + GK A + +N
Sbjct: 148 ADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQ 207
Query: 104 -QNGCTPLHYAASK---NRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILL 159
Q+ T LH A + R ++A +LL GAN + K+ T +H AA + + ++ +L
Sbjct: 208 PQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLH 267
Query: 160 YYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLI 219
+ A N D+ G T LH A ++ +LL+S G+ I + + T Q+ + I
Sbjct: 268 KHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQI 327
Query: 220 L 220
L
Sbjct: 328 L 328
Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 50/103 (48%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
L A S N ++ +L N A D ++T +H AA ++++ +LL + A + +D
Sbjct: 29 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKD 88
Query: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
G PLH AC E +LL+ GA + + + TPL A
Sbjct: 89 KGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEA 131
Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 45/91 (49%)
Query: 18 KLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPL 77
K +++ E +L + ++D T LH A H +++E L + G +N D G + L
Sbjct: 225 KRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTAL 284
Query: 78 HIAASAGRDEIVKALLGKGAQVNAVNQNGCT 108
H AA AG + + LL G+ + ++ G T
Sbjct: 285 HRAALAGHLQTCRLLLSYGSDPSIISLQGFT 315
>6AUN-A nrPDB
Length = 752
Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 68/246 (27%), Positives = 107/246 (43%), Gaps = 41/246 (16%)
Query: 2 EGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFL-L 60
EGC + C S L EL + A + TD TA H+A ++++++ L
Sbjct: 151 EGCTPLHLACRKGDSEILVELVQYCHAQMDV---TDNKGETAFHYAVQGDNSQVLQLLGK 207
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAV-------------NQNGC 107
+N + G +PLH+A G+ E+V+ LL A+ N + +Q GC
Sbjct: 208 NASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGC 267
Query: 108 ---------------------TPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRA 146
+PLH+A + E+A MLL+ G + D+ TA+H A
Sbjct: 268 AEMIISMDSSQIHSKDPRYGASPLHWAKNA---EMARMLLKRGCDVDSTSAAGNTALHVA 324
Query: 147 AAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEK 206
+ + +LL Y A+ GNTPLHLA ++ +E K L+ GA + N +
Sbjct: 325 VMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGE 384
Query: 207 TPLQVA 212
TP +A
Sbjct: 385 TPAFMA 390
Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 3/106 (2%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
+ LHWA +A E+ LL+ G V+ AG + LH+A R + V LL GA
Sbjct: 289 SPLHWAKNA---EMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGT 345
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAA 147
++G TPLH A SK+ E+ L+ GA D + + T A+
Sbjct: 346 PGEHGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMAS 391
Score = 53.5 bits (127), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 7/143 (4%)
Query: 52 HTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLH 111
H E+++ L L + W+ H+A G E + N+ GCTPLH
Sbjct: 103 HVEVLQHLSDL-----IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLH 157
Query: 112 YAASKNRHEIAVMLLE-GGANPDAKDHYEATAMHRAAAKGNLKMIHIL-LYYKASTNIQD 169
A K EI V L++ A D D+ TA H A N +++ +L A N +
Sbjct: 158 LACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVN 217
Query: 170 TEGNTPLHLACDEERVEEAKLLV 192
+G TPLHLAC + E ++L+
Sbjct: 218 KQGLTPLHLACQMGKQEMVRVLL 240
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 54/215 (25%), Positives = 94/215 (43%), Gaps = 10/215 (4%)
Query: 15 YSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGW 74
Y ++ L +L S R+ S T H A G E + + +++ G
Sbjct: 95 YESSVQVLHVEVLQHLSDLIRS-HPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGC 153
Query: 75 SPLHIAASAGRDEIVKALLGK-GAQVNAVNQNGCTPLHYAASKNRHEIAVML-LEGGANP 132
+PLH+A G EI+ L+ AQ++ + G T HYA + ++ +L A
Sbjct: 154 TPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGL 213
Query: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192
+ + T +H A G +M+ +LL A N+ G P+H A + A++++
Sbjct: 214 NQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSG-FPIHTAMKFSQKGCAEMII 272
Query: 193 SQGASIYIENKEEK---TPLQVAKGG--LGLILKR 222
S +S I +K+ + +PL AK ++LKR
Sbjct: 273 SMDSS-QIHSKDPRYGASPLHWAKNAEMARMLLKR 306
Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 29/91 (31%), Positives = 43/91 (47%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
TALH A + V LL G + G +PLH+A S E++KAL+ GA+V+
Sbjct: 319 TALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVDT 378
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
N G TP A+ ++ +M + P
Sbjct: 379 PNDFGETPAFMASKISKQLQDLMPISRARKP 409
>4OT9-A nrPDB
Length = 359
Score = 80.1 bits (196), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 65/192 (33%), Positives = 94/192 (48%), Gaps = 13/192 (6%)
Query: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA--ASAGRD 86
D + T+ +T LH A G T +V FLL++G D G S +H+A A AG
Sbjct: 110 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 169
Query: 87 EIVKALLGKGAQVNAVNQ-------NGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
E+++ALL GA AV Q G P+H A E +L++ GA +A +
Sbjct: 170 ELLRALLQSGAP--AVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQG 227
Query: 140 A-TAMHRAAAKGNLKMI-HILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 197
TA+H A L ++ H++ +A+ N + GNTPLHLA +LL+ GA
Sbjct: 228 GRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD 287
Query: 198 IYIENKEEKTPL 209
I+ EN+E PL
Sbjct: 288 IHAENEEPLCPL 299
>4Z68-A nrPDB
Length = 155
Score = 79.7 bits (195), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 52/137 (37%), Positives = 77/137 (56%), Gaps = 3/137 (2%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGW--SPLHIAASAGRDEIVKALLGKGAQVNAVNQ 104
A AG E V+ L + VN +D G +PLH AA R +V+ LL GA V+A ++
Sbjct: 10 AAKAGDVETVKKLCTVQ-SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 68
Query: 105 NGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAS 164
G PLH A S +E+A +L++ GA + D ++ T +H AAAKG ++ +LL + A
Sbjct: 69 GGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGAD 128
Query: 165 TNIQDTEGNTPLHLACD 181
++ +GNTPL L D
Sbjct: 129 PTKKNRDGNTPLDLVKD 145
Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 45/123 (36%), Positives = 65/123 (52%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A +G +E +K+ + T LH+A +VE+LLQ G V+ KD G
Sbjct: 11 AKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGG 70
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
PLH A S G E+ + L+ GA VN + TPLH AA+K ++EI +LL+ GA+P
Sbjct: 71 LVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPT 130
Query: 134 AKD 136
K+
Sbjct: 131 KKN 133
Score = 70.9 bits (172), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Query: 80 AASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHY 138
AA AG E VK L + + TPLH+AA NR + LL+ GA+ AKD
Sbjct: 10 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 69
Query: 139 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
+H A + G+ ++ +L+ + A N+ D TPLH A + + E KLL+ GA
Sbjct: 70 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 129
Query: 199 YIENKEEKTPLQVAKGG 215
+N++ TPL + K G
Sbjct: 130 TKKNRDGNTPLDLVKDG 146
Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 33/74 (44%), Positives = 43/74 (58%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
D+ LH ACS GH E+ E L++ G VN D ++PLH AA+ G+ EI K LL G
Sbjct: 67 DKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHG 126
Query: 97 AQVNAVNQNGCTPL 110
A N++G TPL
Sbjct: 127 ADPTKKNRDGNTPL 140
Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 19/66 (28%), Positives = 29/66 (43%)
Query: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
E+ E ++ ++ D T LH A + G EI + LLQ G K+ G +PL +
Sbjct: 84 EVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV 143
Query: 81 ASAGRD 86
D
Sbjct: 144 KDGDTD 149
>5CBO-A nrPDB
Length = 176
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 48/123 (39%), Positives = 69/123 (56%), Gaps = 3/123 (2%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
AA AG+D+ V+ L+ GA VNA++ G TPLH AA EI +LL+ GA+ +A D
Sbjct: 10 AAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASDATG 69
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV---SQGA 196
T +H AA G L ++ +LL Y A N QD G T ++ D + A++L +Q A
Sbjct: 70 DTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKAQQA 129
Query: 197 SIY 199
+ Y
Sbjct: 130 AFY 132
Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 48/117 (41%), Positives = 63/117 (53%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A AG + V L+ G VN D+ G +PLH+AA G EIV+ LL GA VNA + G
Sbjct: 10 AAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASDATG 69
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
TPLH AA I +LL+ GA+ +A+D + TA + GN + IL KA
Sbjct: 70 DTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKA 126
Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 41/112 (36%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A++G+ +E++ ++A+ + D T LH A GH EIVE LL+ G VN D G
Sbjct: 11 AHAGQDDEVR-ILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASDATG 69
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
+PLH+AA G IV+ LL GA VNA ++ G T + ++A +L
Sbjct: 70 DTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEIL 121
Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 29/89 (32%), Positives = 51/89 (57%)
Query: 124 MLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEE 183
+L+ GA+ +A D++ T +H AA G+ +++ +LL Y A N D G+TPLHLA
Sbjct: 21 ILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASDATGDTPLHLAAKWG 80
Query: 184 RVEEAKLLVSQGASIYIENKEEKTPLQVA 212
+ ++L+ GA + ++K KT ++
Sbjct: 81 YLGIVEVLLKYGADVNAQDKFGKTAFDIS 109
>3EU9-A nrPDB
Length = 240
Score = 77.0 bits (188), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 52/147 (35%), Positives = 78/147 (53%), Gaps = 4/147 (2%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
T LHWA GH +V L++ G + D G S +H+AA G IV L+ KG V+
Sbjct: 78 TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDM 137
Query: 102 VNQNGCTPLHYAASKNRHEI--AVMLLEGGANPDAKDHY-EATAMHRAAAKGNLKMIHIL 158
++QNG TPL +AA + H + +LL + + D Y + TA+H A GN +I +L
Sbjct: 138 MDQNGMTPLMWAAYRT-HSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLL 196
Query: 159 LYYKASTNIQDTEGNTPLHLACDEERV 185
L A+ + Q+ +G + L LA + V
Sbjct: 197 LEAGANVDAQNIKGESALDLAKQRKNV 223
Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 50/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVND-KDDAGWSPLHIAASAGRDEIVKALLGK 95
D+++ T LHWA ++V++ + G V+ D +PLH A G +V L+
Sbjct: 39 DKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKY 98
Query: 96 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKG-NLKM 154
GA + ++ GC+ +H AA I L+ G + D D T + AA + ++
Sbjct: 99 GADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDP 158
Query: 155 IHILLYYKASTNIQDT-EGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
+LL + S N+ D NT LH A LL+ GA++ +N + ++ L +AK
Sbjct: 159 TRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAK 218
Score = 60.8 bits (146), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 2/162 (1%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN- 105
A G E L++ G V D + LH AA R ++VK + KGA V+ + +
Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 75
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 165
TPLH+A + + V L++ GA+P D + +H AA G+ ++ L+
Sbjct: 76 NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 135
Query: 166 NIQDTEGNTPLHLAC-DEERVEEAKLLVSQGASIYIENKEEK 206
++ D G TPL A V+ +LL++ S+ + +K K
Sbjct: 136 DMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHK 177
Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 1/134 (0%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA-KDHY 138
A G E + L+ G V ++ T LH+AA NR ++ + GA D
Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 75
Query: 139 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
+T +H A +G+L M+ L+ Y A ++ D EG + +HLA L+++G +
Sbjct: 76 NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 135
Query: 199 YIENKEEKTPLQVA 212
+ ++ TPL A
Sbjct: 136 DMMDQNGMTPLMWA 149
>5ET1-A nrPDB
Length = 353
Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/182 (32%), Positives = 93/182 (51%), Gaps = 7/182 (3%)
Query: 38 QDSRTAL--HWACSAGHTEIVEFLLQ-LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLG 94
+DS AL H A +G + +L++ + +P + G +P H AA+ G ++ LL
Sbjct: 33 RDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLT 92
Query: 95 KGA-QVNAVNQNGCTPLHYAASKNRHEIAVMLL-EGGANPDAKDHYEATAMHRAAAKGNL 152
+G +V + +G T LH AA ++ LL +GGAN A +H AAAKG+L
Sbjct: 93 QGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDL 152
Query: 153 KMIHILL-YYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQ 210
+ +L+ +Y N Q G TPL+LAC E +E K LV + A ++ ++ TPL
Sbjct: 153 PSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLH 212
Query: 211 VA 212
A
Sbjct: 213 AA 214
Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 64/214 (29%), Positives = 96/214 (44%), Gaps = 38/214 (17%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLL-QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
D T LH A GH ++V++LL Q G D G P+H AA+ G +K L+G
Sbjct: 102 DNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGH 161
Query: 96 GAQ-VNAVNQNGCTPLHYAASKNRHEIAVMLLEG----------------------GANP 132
+ VNA NG TPL+ A + E+ L++ G NP
Sbjct: 162 YPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNP 221
Query: 133 -------------DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
+DH ATAMH AA++G+ K++ LL + A + QD G TPLH A
Sbjct: 222 VLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS-QDLWGGTPLHDA 280
Query: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
+ +E ++L GA + + + + T +A+
Sbjct: 281 AENGELECCQILAVNGAGLDVRDHDGYTAADLAE 314
Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 2/115 (1%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
QD T LH A GH ++ +L+ V +++D G + +H AAS G +++ LL G
Sbjct: 205 QDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHG 264
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGN 151
A+++ + G TPLH AA E +L GA D +DH TA A G+
Sbjct: 265 AEISQ-DLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGH 318
Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Query: 27 LADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRD 86
AD S + + D D TA+H+A S GHT+++ +LL G ++ +D G +PLH AA G
Sbjct: 229 FADVSFSEQ-DHDGATAMHFAASRGHTKVLSWLLLHGAEIS-QDLWGGTPLHDAAENGEL 286
Query: 87 EIVKALLGKGAQVNAVNQNGCT 108
E + L GA ++ + +G T
Sbjct: 287 ECCQILAVNGAGLDVRDHDGYT 308
>5GP7-A nrPDB
Length = 169
Score = 73.6 bits (179), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 2/116 (1%)
Query: 66 VNDKDDAGW--SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAV 123
+N +D G +PLH+AA E+ + LL GA VNA ++ G PLH AAS +IA
Sbjct: 34 INCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA 93
Query: 124 MLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
+L++ +A D + T +H AA KG ++ +LL + A +++ EG TPL LA
Sbjct: 94 LLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149
Score = 70.9 bits (172), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 40/105 (38%), Positives = 60/105 (57%)
Query: 108 TPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNI 167
TPLH AA N E+A LLE GA+ +A+D +H AA+ G++ + +L+ Y N
Sbjct: 45 TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNA 104
Query: 168 QDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
D TPLH A + R + LL++ GA ++N+E +TPL +A
Sbjct: 105 TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149
Score = 70.1 bits (170), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 42/109 (38%), Positives = 58/109 (53%)
Query: 40 SRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQV 99
+ T LH A + E+ E+LL+ G VN +D G PLH AAS G +I L+ V
Sbjct: 43 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCV 102
Query: 100 NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAA 148
NA ++ TPLH AA K R ++ +LL GA+P K+ T + A A
Sbjct: 103 NATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATA 151
Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 33/97 (34%), Positives = 46/97 (47%)
Query: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
E+ E +L + D+ LH A S GH +I L++ VN D ++PLH A
Sbjct: 57 EVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEA 116
Query: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKN 117
A GR ++ LL GA NQ G TPL A + +
Sbjct: 117 AQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD 153
Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 26/73 (35%), Positives = 35/73 (47%)
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
+T +H AA NL++ LL + A N QD G PLH A V+ A LL+ +
Sbjct: 44 STPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 103
Query: 200 IENKEEKTPLQVA 212
+K TPL A
Sbjct: 104 ATDKWAFTPLHEA 116
>3ZKJ-A nrPDB
Length = 261
Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 52/169 (30%), Positives = 84/169 (49%), Gaps = 2/169 (1%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
+ +H A GH + L+ G VN SPLH A G VK LL GAQVN
Sbjct: 5 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 64
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
V + TPL A + +LL+ GA+ + A+ +H AA +G+++ ++ L+ Y
Sbjct: 65 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDL-ASPIHEAARRGHVECVNSLIAY 123
Query: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQ 210
+ + + + TPL+LAC+ ++ K L+ GA + + K + +PL
Sbjct: 124 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLH 171
Score = 60.1 bits (144), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
D + LH AC GH V+ LL+ G VN +PL A +G + V LL GA
Sbjct: 35 DHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGAS 94
Query: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
V + +P+H AA + E L+ G N D K + T ++ A + L
Sbjct: 95 VQP-ESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKL 153
Query: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
L A N Q ++PLH E A LL+ GA +N E K P+++
Sbjct: 154 LESGADVN-QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 205
Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Query: 25 SILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAG 84
++L + + + D + +H A GH E V L+ G ++ K +PL++A
Sbjct: 86 NLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQ 145
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
+ VK LL GA VN + +PLH A E+A +L++ GA+ AK+
Sbjct: 146 QRACVKKLLESGADVNQ-GKGQDSPLHAVARTASEELACLLMDFGADTQAKN 196
>4OAU-C nrPDB
Length = 699
Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 66/201 (32%), Positives = 99/201 (49%), Gaps = 18/201 (8%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
T LH A +IVE LL+ G + G +P +AA AG +++K L KGA VN
Sbjct: 41 TPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNE 100
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE----------ATAMHRAAAKGN 151
+ G T AA + + L + GAN + + + ATA+ AA KG+
Sbjct: 101 CDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGH 160
Query: 152 LKMIHILL-YYKASTNIQDTEG-NTPLH--LACDEERVEE-AKLLVSQGASIYIENKEEK 206
++++ ILL A N D G N +H L+ D+ VE LL+ GA + + + K
Sbjct: 161 VEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGK 220
Query: 207 TPLQVA--KGGLGLILKRMVE 225
TPL +A K LGL+ +R++E
Sbjct: 221 TPLILAVEKKHLGLV-QRLLE 240
Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 12/158 (7%)
Query: 53 TEIVEFLLQLGVPVN-DKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLH 111
++V+ LL+ G VN +++ GW+PLH A R++IV+ LL GA +NG TP
Sbjct: 18 VDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFI 77
Query: 112 YAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNI---- 167
AA ++ + L GA+ + D Y TA AA G +K + L A+ N+
Sbjct: 78 LAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKT 137
Query: 168 -QDTE-----GNTPLHLACDEERVEEAKLLVSQ-GASI 198
+D E G T L A ++ VE K+L+ + GA +
Sbjct: 138 KEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADV 175
Score = 60.5 bits (145), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 42/130 (32%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 87 EIVKALLGKGAQVNAVNQNG-CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHR 145
++V+ LL GA VN + G TPLH A +R +I +LL GA+P + AT
Sbjct: 19 DLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFIL 78
Query: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
AA G++K++ + L A N D G T A +V+ K L +GA++ + K +
Sbjct: 79 AAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTK 138
Query: 206 KTPLQVAKGG 215
+ ++ KGG
Sbjct: 139 EDQERLRKGG 148
Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 15/168 (8%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN- 100
T A AG ++++ L G VN+ D G++ AA G+ + +K L +GA VN
Sbjct: 74 TPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNL 133
Query: 101 ---------AVNQNGCTPLHYAASKNRHEIAVMLL-EGGANPDAKDHYEATAMHRAAAKG 150
+ + G T L AA K E+ +LL E GA+ +A D+ A+ A
Sbjct: 134 RRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSS 193
Query: 151 NLK----MIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ + H+LL + A N++ G TPL LA +++ + + L+ Q
Sbjct: 194 DDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQ 241
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 52/172 (30%), Positives = 81/172 (47%), Gaps = 16/172 (9%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVN----DKDD------AGWSPLHIAASAGRDEIVKA 91
TA A G + ++FL + G VN K+D G + L AA G E++K
Sbjct: 107 TAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKI 166
Query: 92 LLGK-GAQVNAVNQNGCTPLHYAA----SKNRHEIAVMLLEGGANPDAKDHYEATAMHRA 146
LL + GA VNA + G L +A + I +LL+ GA+ + + T + A
Sbjct: 167 LLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILA 226
Query: 147 AAKGNLKMIHILLYYK-ASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 197
K +L ++ LL + N D++G T L LA + + + A+LL +GAS
Sbjct: 227 VEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGAS 278
Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 39/134 (29%)
Query: 42 TALHWACSAGHTEIVEFLL-QLGVPVNDKDDAGWSPLHIAASAGRDEIVKA----LLGKG 96
TAL A GH E+++ LL ++G VN D+ G + L A + D V+A LL G
Sbjct: 150 TALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHG 209
Query: 97 AQVNAVNQNGCTPLHYAASKNR----------------------------------HEIA 122
A VN + G TPL A K +IA
Sbjct: 210 ADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIA 269
Query: 123 VMLLEGGANPDAKD 136
+L + GA+ D D
Sbjct: 270 ELLCKRGASTDCGD 283
>1G3N-B nrPDB
Length = 168
Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 36/78 (46%), Positives = 43/78 (55%)
Query: 120 EIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
EIA LL GANPD KD +H AA G L + LL ++A NI+D EGN PLHLA
Sbjct: 51 EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
Query: 180 CDEERVEEAKLLVSQGAS 197
E + + LV AS
Sbjct: 111 AKEGHLRVVEFLVKHTAS 128
Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ-LGVPVN 67
++ + A +G L+ L +++L ++ D + LH A GH +VEFL++ V
Sbjct: 73 VIHDAARAGFLDTL-QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131
Query: 68 DKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
++ G + +A GR+E+V + GA
Sbjct: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161
>5D68-A nrPDB
Length = 486
Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 40/122 (32%), Positives = 68/122 (55%), Gaps = 7/122 (5%)
Query: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANPDA 134
PLH +A G E++ LL + VN ++ + P+HYA + E +LLE G NP+
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERV----EEAK 189
+ ++ +H AA G+ +++ ILL + + +I D +G +PL++ C+E + E AK
Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNNWEEAAK 159
Query: 190 LL 191
LL
Sbjct: 160 LL 161
Score = 50.1 bits (118), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 30 KSLATRTDQDSRT-----ALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAG 84
+S+++ T+ R LH + G +E++ LL VN D W+P+H A G
Sbjct: 23 RSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYG 82
Query: 85 RDEIVKALLGKG-AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
+ E + LL KG N +N +PLH+AA EI +LL +P+ H
Sbjct: 83 KVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN---HPETDRH 133
Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Query: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHI 79
EL +L+++ + D D +H+AC G E LL+ G N + SPLH
Sbjct: 52 ELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHF 111
Query: 80 AASAGRDEIVKALLGKG-AQVNAVNQNGCTPLHYA---ASKNRHEIAVMLLEGGANPDAK 135
AA G EIV+ LL + +Q G +PL+ N E A +L E P
Sbjct: 112 AAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKP--- 168
Query: 136 DHYEATAMHR 145
YE ++R
Sbjct: 169 --YEKVRIYR 176
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Query: 142 AMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG-ASIYI 200
+HR+A +G+ +++ LL + S N D++ P+H AC +VE ++L+ +G + +
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 201 ENKEEKTPLQVAKGG 215
N + +PL A GG
Sbjct: 101 LNGQLSSPLHFAAGG 115
>4O1O-A nrPDB
Length = 717
Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Query: 87 EIVKALLGKGAQVNAVNQN-GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHR 145
E V+ LL +GA N + G +PLH A + ++ +LL+ GA+P + AT
Sbjct: 22 EQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKRNGATPFII 81
Query: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
A GN++++ +LL N D G T A RVE + L GA + + K +
Sbjct: 82 AGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTK 141
Query: 206 KTPLQVAKGG 215
+ ++ KGG
Sbjct: 142 QDQERIRKGG 151
Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 63/227 (27%), Positives = 92/227 (40%), Gaps = 49/227 (21%)
Query: 47 ACSAGHTEIVEFLLQLGVPVN-DKDDAGWSPLHIAASAGRDEIVKALLGKGA-------- 97
A E V LL+ G N +++ GWSPLH A +++V LL GA
Sbjct: 15 AVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKRN 74
Query: 98 -------------------------QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
VN + NG T AA R E L E GA+
Sbjct: 75 GATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADV 134
Query: 133 D----AKDHYE------ATAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLAC- 180
+ K E ATA+ AA KG++ ++ ILL+ KA + +D G L A
Sbjct: 135 NMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALL 194
Query: 181 --DEERVEE-AKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
D+ + + +LL+ GA + + + KTPL +A L L +M+
Sbjct: 195 NPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQML 241
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 58/178 (32%), Positives = 79/178 (44%), Gaps = 18/178 (10%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVN----DKDD------AGWSPLHIAASAGRD 86
D + TA A G E + FL + G VN K D G + L AA G
Sbjct: 105 DVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHV 164
Query: 87 EIVKALL-GKGAQVNAVNQNGCTPLHYAA----SKNRHEIAVMLLEGGANPDAKDHYEAT 141
+V LL A+V+A + G L YA I +LL+ GA+ + + T
Sbjct: 165 GVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGADVNVRGEGSKT 224
Query: 142 AMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERVEE-AKLLVSQGAS 197
+ A + NL ++ +LL + N D EG T L LA E R+EE AKLL +GAS
Sbjct: 225 PLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAV-ELRLEEIAKLLCHRGAS 281
>5DND-A nrPDB
Length = 588
Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 36/105 (34%), Positives = 59/105 (56%), Gaps = 1/105 (0%)
Query: 50 AGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTP 109
AG E ++ L++LG + KD G + LH+AA GRD +V LL +G VNA +++G +P
Sbjct: 432 AGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSP 491
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEA-TAMHRAAAKGNLK 153
L A E +L + GA +D +A T + R A++ +++
Sbjct: 492 LLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADME 536
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 2/147 (1%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
LA++G+LE L+ + L + D + +T LH A G +V LL G+ VN +D
Sbjct: 429 LAHAGELEALQALMELGSDLRLK-DSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRD 487
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVN-QNGCTPLHYAASKNRHEIAVMLLEGGAN 131
G SPL +A E ++ L GA ++ + ++ T L AS+ E + GA+
Sbjct: 488 GLSPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQAGAD 547
Query: 132 PDAKDHYEATAMHRAAAKGNLKMIHIL 158
+ +A+ A A GN +++ +L
Sbjct: 548 LQQPGYDGRSALCVAEAAGNQEVLALL 574
Score = 37.0 bits (84), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 27/89 (30%), Positives = 43/89 (48%)
Query: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
A AG E ++AL+ G+ + + NG T LH AA R + MLL G + +A+D
Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489
Query: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQD 169
+ + A + + I +L A + QD
Sbjct: 490 SPLLLAVQGRHRECIRLLRKAGACLSPQD 518
Score = 30.0 bits (66), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 17/69 (24%), Positives = 34/69 (49%)
Query: 147 AAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEK 206
A G L+ + L+ + ++D+ G T LH+A R +L+ +G + +++
Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489
Query: 207 TPLQVAKGG 215
+PL +A G
Sbjct: 490 SPLLLAVQG 498
>6EMK-G nrPDB
Length = 426
Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 40/129 (31%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 88 IVKALLGKGAQV--NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD--AKDHYEATAM 143
IVK LL + + N ++NG + LHYA+ R+ I V L++ G + K T +
Sbjct: 20 IVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCV 79
Query: 144 HRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202
H A KG+ + +H+LL + N + G P+H+AC + + LL+ GA +++ +
Sbjct: 80 HLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMD 139
Query: 203 KEEKTPLQV 211
TPL V
Sbjct: 140 TNGDTPLHV 148
Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 10/117 (8%)
Query: 42 TALHWACSAGHTEIVEFLLQ-LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN 100
T +H A GH + + LLQ +N + + G +P+HIA + + L+G GA +
Sbjct: 77 TCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLW 136
Query: 101 AVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
++ NG TPLH MLL G E + KGN K I +
Sbjct: 137 VMDTNGDTPLHVCLEYGSISCMKMLLNEG---------EVSLDDNVRDKGNWKPIDV 184
Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 16/59 (27%), Positives = 29/59 (49%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
++ R +H AC + + + L+ +G + D G +PLH+ G +K LL +G
Sbjct: 107 ENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEG 165
>3EHQ-A nrPDB
Length = 222
Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL-QLGVPVNDKDDA 72
A G L L+E L ++ D+ TAL+WAC GH +IVE L Q + +N ++
Sbjct: 81 AKRGNLSWLRE-CLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQQNKL 139
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
G + LH AA G +IV+ LL KGA+ + N
Sbjct: 140 GDTALHAAAWKGYADIVQLLLAKGARTDLRN 170
Score = 34.3 bits (77), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 32/138 (23%), Positives = 56/138 (40%), Gaps = 32/138 (23%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
+PLH AA G ++ L VN +++ G T L++A +I ML
Sbjct: 75 NPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLF-------- 126
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ N+++ N Q+ G+T LH A + + +LL+++
Sbjct: 127 -------------TQPNIEL-----------NQQNKLGDTALHAAAWKGYADIVQLLLAK 162
Query: 195 GASIYIENKEEKTPLQVA 212
GA + N E+K +A
Sbjct: 163 GARTDLRNIEKKLAFDMA 180
>2KXP-C nrPDB
Length = 118
Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 16 SGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
+G L+E+K+ + A RT + R LH+A G EI+EFLL G +N D +
Sbjct: 12 NGDLDEVKDYV-AKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHIT 70
Query: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPL 110
PL A G VK LL KGA +G T L
Sbjct: 71 PLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105
Score = 50.1 bits (118), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 36/101 (35%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 46 WACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 105
WA G + V+ + G VN + G PLH AA G+ EI++ LL KGA +NA +++
Sbjct: 8 WALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKH 67
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGAN-----PDAKDHYEAT 141
TPL A + +LL GA+ PD EAT
Sbjct: 68 HITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEAT 108
Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 30/88 (34%), Positives = 45/88 (51%)
Query: 89 VKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAA 148
VK + KG VN + G PLHYAA + EI LL GA+ +A D + T + A
Sbjct: 18 VKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVY 77
Query: 149 KGNLKMIHILLYYKASTNIQDTEGNTPL 176
+G++ + +LL A ++ +G T L
Sbjct: 78 EGHVSCVKLLLSKGADKTVKGPDGLTAL 105
Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 10/85 (11%)
Query: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV 185
LEGG P +H AA G L+++ LL A N D TPL A E V
Sbjct: 32 LEGGRKP----------LHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHV 81
Query: 186 EEAKLLVSQGASIYIENKEEKTPLQ 210
KLL+S+GA ++ + T L+
Sbjct: 82 SCVKLLLSKGADKTVKGPDGLTALE 106
>5U0J-A nrPDB
Length = 140
Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
M V NL+ AY+G + L+ L+ + R D DSRTALH A + GH E+V+FLL
Sbjct: 21 MVKSVINLLFA--AYTGDVSALRRFALSAMDMEQR-DYDSRTALHVAAAEGHVEVVKFLL 77
Query: 61 QLGVPVNDKDDAGW--SPLHIAASAGRDEIVKAL 92
+ VN W +P+ A G ++ K L
Sbjct: 78 E-ACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 110
Score = 31.2 bits (69), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 108 TPLHYAASKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
T LH AA++ E+ LLE NP KD + T M A G+ + IL Y+
Sbjct: 59 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYT 118
Query: 167 IQDTEGN 173
Q N
Sbjct: 119 PQGDSDN 125
Score = 27.7 bits (60), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPL 176
+D+ TA+H AAA+G+++++ LL K + +D NTP+
Sbjct: 53 RDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPM 95
>1BD8-A nrPDB
Length = 156
Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
Query: 51 GHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPL 110
G T I LL+ G N +D +G SP+H AA G + +K L+ GA VN + G P+
Sbjct: 46 GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPI 105
Query: 111 HYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
H A + H V L ++ +D T + A +G ++ IL
Sbjct: 106 HLAVQEG-HTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 152
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
AA + E+ +L +PDA + + TA+ + G+ + LL AS N+QDT G
Sbjct: 10 AARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSTAIALELLKQGASPNVQDTSG 68
Query: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
+P+H A ++ K+LV GA + + + P+ +A
Sbjct: 69 TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLA 108
>5U0K-A nrPDB
Length = 141
Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 36/91 (39%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 4 CVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG 63
V NL+ AYSG + L+ L+ + + D DSRTALH A + GH E+V+FL++
Sbjct: 25 TVVNLLFA--AYSGDVSALRRFALSAMDMEQK-DYDSRTALHVAAAEGHIEVVKFLIE-A 80
Query: 64 VPVND--KDDAGWSPLHIAASAGRDEIVKAL 92
VN KD G PL A E+VK L
Sbjct: 81 CKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111
Score = 33.5 bits (75), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERVEEAKLL 191
KD+ TA+H AAA+G+++++ L+ K + +D GN PL A +E KLL
Sbjct: 54 KDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111
Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG-GANPDAK 135
L AA +G ++ + + + T LH AA++ E+ L+E NP AK
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTE 171
D + + A +L+++ +L Y+ S + +T+
Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTLSETQ 124
Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVN--AVNQNGCTPLHYAASKNRHEIAVMLL 126
KD + LH+AA+ G E+VK L+ + +VN A ++ G PL A N E+ +L
Sbjct: 54 KDYDSRTALHVAAAEGHIEVVKFLI-EACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL- 111
Query: 127 EGGANPDAKDHY 138
D +D Y
Sbjct: 112 -----QDYQDSY 118
>5UQE-A nrPDB
Length = 520
Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 5 VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV 64
V NL+ AY+G + L+ L+ + R D DSRTALH A + GH E+V+FLL+
Sbjct: 418 VINLLFA--AYTGDVSALRRFALSAMDMEQR-DYDSRTALHVAAAEGHVEVVKFLLE-AC 473
Query: 65 PVNDKDDAGW--SPLHIAASAGRDEIVKAL 92
VN W +P+ A G ++ K L
Sbjct: 474 KVNPFPKDRWNNTPMDEALHFGHHDVFKIL 503
Score = 32.0 bits (71), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 108 TPLHYAASKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
T LH AA++ E+ LLE NP KD + T M A G+ + IL Y+
Sbjct: 452 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYT 511
Query: 167 IQDTEGN 173
Q N
Sbjct: 512 PQGDSDN 518
Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 15/45 (33%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 133 DAKDHYEATAMHRAAAKGNLKMIHILL-YYKASTNIQDTEGNTPL 176
+ +D+ TA+H AAA+G+++++ LL K + +D NTP+
Sbjct: 444 EQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPM 488
>3LJN-A nrPDB
Length = 364
Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 30/187 (16%)
Query: 35 RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLG 94
++D ++ +H A G T+ V L++ GV ++ G + LH+A G + K L
Sbjct: 15 KSDDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLAS 74
Query: 95 KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKM 154
G +V+++ +G P+H A N+ ++ V L+EG AK +M
Sbjct: 75 VG-EVHSL-WHGQKPIHLAVMANKTDLVVALVEG-------------------AKERGQM 113
Query: 155 IHILL-------YYKASTNIQDTEGNTPLH--LACDEERVEEAKLLVSQGASIYIENKEE 205
LL + ++++ +G T LH + E +E K+LV GAS ++K +
Sbjct: 114 PESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKAD 173
Query: 206 KTPLQVA 212
+TPL A
Sbjct: 174 ETPLMRA 180
Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 58/245 (23%), Positives = 109/245 (44%), Gaps = 40/245 (16%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
A G+ +E++ I S T ++ TALH AC G + ++L +G + +
Sbjct: 28 ARKGQTDEVRRLIETGVS-PTIQNRFGCTALHLACKFGCVDTAKYLASVG-----EVHSL 81
Query: 74 W---SPLHIAASAGRDEIVKALLGKGA-----------------QVNAVNQN-----GCT 108
W P+H+A A + ++V AL+ +GA +VN + + G T
Sbjct: 82 WHGQKPIHLAVMANKTDLVVALV-EGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQT 140
Query: 109 PLHYAASKNRH--EIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST- 165
LH+ E+ +L++ GA+P AKD + T + RA N + + +++ S
Sbjct: 141 ALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKS 200
Query: 166 ----NIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA-KGGLGLIL 220
+ + +GN+ LH A + A V G + +E+ E PL ++ + + L+
Sbjct: 201 SLRLDYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLT 260
Query: 221 KRMVE 225
K +++
Sbjct: 261 KELLQ 265
Score = 30.0 bits (66), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 15/59 (25%), Positives = 30/59 (50%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
++ + LHWA ++ +++G+ VN +D+ PL+++ A + K LL K
Sbjct: 208 NKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELLQK 266
>1BLX-B nrPDB
Length = 166
Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 59 LLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNR 118
LL+ G N +D +G SP+H AA G + +K L+ GA VNA++ G P+H A +
Sbjct: 60 LLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREG- 118
Query: 119 HEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
H V L ++ +D T + A +G ++ IL
Sbjct: 119 HSSVVSFLAPESDLHHRDASGLTPLELARQRGAQNLMDIL 158
Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Query: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
AA + E+ +L +PDA + + TA+ + G+ + LL AS N+QD G
Sbjct: 16 AARGDVQEVRRLLHRELVHPDALNRFGKTAL-QVMMFGSPAVALELLKQGASPNVQDASG 74
Query: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
+P+H A ++ K+LV GA + + P+ +A
Sbjct: 75 TSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLA 114
>5UIL-A nrPDB
Length = 405
Score = 46.6 bits (109), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 29/117 (24%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
AC ++ + L++ + +K+ GWSP+ +AA G E++K L+ KGA +N N G
Sbjct: 285 ACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKG 344
Query: 107 CTPLHYAAS----KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILL 159
T Y + ML++ G + D+ + T GN ++ ++
Sbjct: 345 TTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQYMM 401
>3T9K-A nrPDB
Length = 390
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/88 (36%), Positives = 40/88 (45%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
QD+ T L A +A EFLLQ G VN D AG PLH A G + L +GA
Sbjct: 233 QDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGA 292
Query: 98 QVNAVNQNGCTPLHYAASKNRHEIAVML 125
+ A + G PL A +I +L
Sbjct: 293 DLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 93 LGKGAQVNAVN--QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKG 150
L GA VN VN Q+ TPL A + N LL+ GAN + D +H A G
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 151 NLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
+ + + L A +D+EG PL +A + + LL
Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 34.3 bits (77), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 23/73 (31%), Positives = 34/73 (46%)
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
AT + +A A +L LL A+ N D+ G PLH A A L + +GA +
Sbjct: 236 ATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLG 295
Query: 200 IENKEEKTPLQVA 212
+ E + PL +A
Sbjct: 296 ARDSEGRDPLTIA 308
Score = 33.1 bits (74), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 30/69 (43%)
Query: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
E +L + + + D R LH A GHT + L+ G + +D G PL IA
Sbjct: 252 EFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMET 311
Query: 84 GRDEIVKAL 92
+IV L
Sbjct: 312 ANADIVTLL 320
Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 39/88 (44%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
+PL A +A + LL GA VN + G PLH+A +A + L+ GA+ A
Sbjct: 237 TPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGA 296
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYK 162
+D + A N ++ +L K
Sbjct: 297 RDSEGRDPLTIAMETANADIVTLLRLAK 324
>6BOA-A nrPDB
Length = 742
Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats.
Identities = 43/156 (27%), Positives = 66/156 (42%), Gaps = 19/156 (12%)
Query: 75 SPLHIAASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA--- 130
SPL +AA + + LL + +V+ G T LH AA + E A++L+E
Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 131 -NPDAKDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTE-------------GNTP 175
P + YE TA+H A N+ ++ LL +AS + + T G P
Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
Query: 176 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
L A E +LL+ GA I ++ T L +
Sbjct: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
Score = 34.3 bits (77), Expect = 0.041, Method: Composition-based stats.
Identities = 40/155 (25%), Positives = 58/155 (37%), Gaps = 51/155 (32%)
Query: 42 TALHWACSAGHTEIVEFLLQLGV-----PVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
TALH A + E L++ P+ + G + LHIA +V+ALL +
Sbjct: 81 TALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARR 140
Query: 97 AQVNA------VNQNGCT-------PLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAM 143
A V+A ++ C PL +AA N EI +L+E GA+ A
Sbjct: 141 ASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRA--------- 191
Query: 144 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHL 178
QD+ GNT LH+
Sbjct: 192 ------------------------QDSLGNTVLHI 202
Score = 31.6 bits (70), Expect = 0.30, Method: Composition-based stats.
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 85
+ +TALH A + +V LL V+ + G PL AA
Sbjct: 116 EGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNS 175
Query: 86 DEIVKALLGKGAQVNAVNQNGCTPLH 111
+EIV+ L+ GA + A + G T LH
Sbjct: 176 EEIVRLLIEHGADIRAQDSLGNTVLH 201
>3UI2-A nrPDB
Length = 244
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
+P AA ++ + LL + V+AV++NG T L + A + +L E GA+ D
Sbjct: 47 TPWWTAARKADEQALSQLL-EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 105
Query: 135 KDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
+D TA+H AA +++ L+ A ++D G T L LA
Sbjct: 106 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151
Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-DAGWSPLHIAASAG 84
+L D+ + D++ RTAL + G + V L + G ++ +D G + LH+AA
Sbjct: 64 LLEDRDVDA-VDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHMAAGYV 122
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
R E+V+AL+ GA + ++ G T L A
Sbjct: 123 RPEVVEALVELGADIEVEDERGLTALELA 151
>1DCQ-A nrPDB
Length = 278
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 9/91 (9%)
Query: 126 LEGGANPDAKDHYEATAMH---RAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDE 182
L G PD TA+H R+ + +L ++ L+ + + Q +G+T LH C
Sbjct: 162 LANGHEPDE------TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLT 215
Query: 183 ERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
+ E KLL+ ASI I N+ +TPL +AK
Sbjct: 216 DNAECLKLLLRGKASIEIANESGETPLDIAK 246
Score = 34.7 bits (78), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 27/154 (17%)
Query: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEI 88
++ A + D+ LH C A T + LLQ A + G D
Sbjct: 116 ERRYARKKHADTAAKLHSLCEAVKTRDIFGLLQ------------------AYADGVDLT 157
Query: 89 VKALLGKGAQVNAVNQNGCTPLHYAA---SKNRHEIAVMLLEGGANPDAKDHYEATAMHR 145
K L G + + T LH A + I L++ N D + +TA+H
Sbjct: 158 EKIPLANGHEPDE------TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHY 211
Query: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
N + + +LL KAS I + G TPL +A
Sbjct: 212 CCLTDNAECLKLLLRGKASIEIANESGETPLDIA 245
>3DEO-A nrPDB
Length = 183
Score = 43.1 bits (100), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
+P AA ++ + LL + V+AV++NG T L + A + +L E GA+ D
Sbjct: 46 TPWWTAARKADEQALSQLL-EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 104
Query: 135 KDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
+D TA+H AA +++ L+ A ++D G T L LA
Sbjct: 105 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Query: 20 EELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-DAGWSPLH 78
E+ +L D+ + D++ RTAL + G + V L + G ++ +D G + LH
Sbjct: 57 EQALSQLLEDRDVDA-VDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALH 115
Query: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
+AA R E+V+AL+ GA + ++ G T L A
Sbjct: 116 MAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
>4XD0-A nrPDB
Length = 417
Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 22/66 (33%), Positives = 34/66 (51%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
AC E + LL+ + +K+ GWSP+ IAA G ++++ L+ KG +N N G
Sbjct: 298 ACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKG 357
Query: 107 CTPLHY 112
T Y
Sbjct: 358 TTVAMY 363
>6E2G-A nrPDB
Length = 727
Score = 40.4 bits (93), Expect = 6e-04, Method: Composition-based stats.
Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 25/157 (15%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 85
+ +TALH A + +V LL G V+ + G PL AA G
Sbjct: 116 EGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGS 175
Query: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA----- 140
+EIV+ L+ GA + A + G T LH + A + + D DH ++
Sbjct: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVP 235
Query: 141 -----TAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
T A +GN+ M L+ + +IQ T G
Sbjct: 236 NNQGLTPFKLAGVEGNIVMFQHLM--QKRKHIQWTYG 270
Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats.
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 25/142 (17%)
Query: 42 TALHWACSAGHTEIVEFLLQLGV-----PVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
TALH A + E L++ P+ + G + LHIA +V+ALL +G
Sbjct: 81 TALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARG 140
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
A V+A + + HY P +Y + AA G+ +++
Sbjct: 141 ASVSA--RATGSVFHY------------------RPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 157 ILLYYKASTNIQDTEGNTPLHL 178
+L+ + A QD+ GNT LH+
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHI 202
Score = 36.2 bits (82), Expect = 0.011, Method: Composition-based stats.
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 108 TPLHYAASKNRHEIAVMLLE-GGANPDAKDHYEATAMHRAAAKGNLKMIHIL------LY 160
+PL AA +N + + LL+ G K TA+H AA NL+ +L L
Sbjct: 47 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 161 YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
++ T+ + EG T LH+A + V + L+++GAS+
Sbjct: 107 FEPMTS-ELYEGQTALHIAVINQNVNLVRALLARGASV 143
>6DMR-A nrPDB
Length = 730
Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats.
Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 27/143 (18%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDA------GWSPLHIAASAGRDEIVKALLGK 95
TALH A + E L++ P K+ A G + LHIA +V+ALL +
Sbjct: 81 TALHVAALYDNLEAATLLME-AAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
Query: 96 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMI 155
GA V+A A ++ H + +Y + AA G+ +++
Sbjct: 140 GASVSARATGA------AFRRSPHNLI--------------YYGEHPLSFAACVGSEEIV 179
Query: 156 HILLYYKASTNIQDTEGNTPLHL 178
+L+ + A QD+ GNT LH+
Sbjct: 180 RLLIEHGADIRAQDSLGNTVLHI 202
Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats.
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 41 RTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGRDE 87
+TALH A + +V LL G V+ + G PL AA G +E
Sbjct: 118 QTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEE 177
Query: 88 IVKALLGKGAQVNAVNQNGCTPLH 111
IV+ L+ GA + A + G T LH
Sbjct: 178 IVRLLIEHGADIRAQDSLGNTVLH 201
Score = 26.9 bits (58), Expect = 7.1, Method: Composition-based stats.
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 141 TAMHRAAAKGNLKMIHILL-----YYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
TA+H AA NL+ +L+ K + G T LH+A + + + L+++G
Sbjct: 81 TALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARG 140
Query: 196 ASI 198
AS+
Sbjct: 141 ASV 143
>4BSZ-B nrPDB
Length = 202
Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 28/142 (19%)
Query: 14 AYSGKLEELKE---SILADKSLAT-RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
A +G L+ LK+ ++++ + L+T + + TALH A + GH E V ++L+ N
Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL-EG 128
+D +KA VN VN+ G T LH+A+ + ++ +L E
Sbjct: 82 ED-----------------LKAF------VNEVNKTGNTALHWASLNGKLDVVKLLCDEY 118
Query: 129 GANPDAKDHYEATAMHRAAAKG 150
A+P ++ + A+ A G
Sbjct: 119 EADPFIRNKFGHDAIFEAENSG 140
Score = 30.8 bits (68), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 11/76 (14%)
Query: 139 EATAMHRAAAKGNLKMIHILLY----------YKASTNIQDTEGNTPLHLACDEERVEEA 188
++TA+H AAA G+++ + +L KA N + GNT LH A +++
Sbjct: 52 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 111
Query: 189 KLLVSQ-GASIYIENK 203
KLL + A +I NK
Sbjct: 112 KLLCDEYEADPFIRNK 127
>2RFA-A nrPDB
Length = 232
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 20/158 (12%)
Query: 74 W-SPLHIAASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA- 130
W SPL +AA + + LL +G +V+ G T LH AA + E A++L+E
Sbjct: 3 WESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 62
Query: 131 ---NPDAKDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDT-------------EGN 173
P + YE TA+H A N+ ++ LL AS + + T G
Sbjct: 63 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 122
Query: 174 TPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
PL A E +LL+ GA I ++ T L +
Sbjct: 123 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 160
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 23/144 (15%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 85
+ +TALH A + +V LL G V+ + G PL AA G
Sbjct: 74 EGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGS 133
Query: 86 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA----- 140
+EIV+ L+ GA + A + G T LH + A + + D DH ++
Sbjct: 134 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVP 193
Query: 141 -----TAMHRAAAKGNLKMIHILL 159
T A +GN+ M L+
Sbjct: 194 NNQGLTPFKLAGVEGNIVMFQHLM 217
Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Query: 42 TALHWACSAGHTEIVEFLLQ-----LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 96
TALH A + E L++ + P+ + G + LHIA +V+ALL +G
Sbjct: 39 TALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARG 98
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
A V+A + + HY P +Y + AA G+ +++
Sbjct: 99 ASVSA--RATGSVFHY------------------RPHNLIYYGEHPLSFAACVGSEEIVR 138
Query: 157 ILLYYKASTNIQDTEGNTPLHL 178
+L+ + A QD+ GNT LH+
Sbjct: 139 LLIEHGADIRAQDSLGNTVLHI 160
>2A5E-A nrPDB
Length = 156
Score = 35.0 bits (79), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
L AA++ R E LLE GA P+A + Y + G+ ++ +LL + A N D
Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74
Query: 170 TEGNT-PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
T P+H A E ++ +L GA + + + + P+ +A+
Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE 119
>5IRX-A nrPDB
Length = 636
Score = 33.5 bits (75), Expect = 0.074, Method: Compositional matrix adjust.
Identities = 44/188 (23%), Positives = 76/188 (40%), Gaps = 49/188 (26%)
Query: 84 GRDEIVKALLGKGAQVNAVNQ-----------NGCTPLHYAASKNRHEIAVMLLEGGANP 132
G+++ + LL + +++ Q G T LH A + + +L+E GA+
Sbjct: 63 GQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADV 122
Query: 133 DAK---DHYEAT-----------AMHRAAAKGNLKMIHILL---YYKASTNIQDTEGNTP 175
A D ++ T + AA L ++ LL + A + +D+ GNT
Sbjct: 123 QAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTV 182
Query: 176 LHLACD--EERVEEAKLLVSQ-------GASIY-------IENKEEKTPLQVAK-----G 214
LH + + V+ K + S GA ++ I N++ TPL +A G
Sbjct: 183 LHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIG 242
Query: 215 GLGLILKR 222
L IL+R
Sbjct: 243 VLAYILQR 250
>1D9S-A nrPDB
Length = 136
Score = 33.5 bits (75), Expect = 0.078, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
L AA++ + E LLE GA+P+A + + + + G+ ++ +LL + A N D
Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPI-QVMMMGSAQVAELLLLHGAEPNCAD 74
Query: 170 TEGNT-PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
T P+H A E ++ +L GA + + + + P+ +A+
Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAE 119
Score = 26.9 bits (58), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 51 GHTEIVEFLLQLGVPVNDKDDAGWS-PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTP 109
G ++ E LL G N D A + P+H AA G + + L GA+++ + G P
Sbjct: 55 GSAQVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLP 114
Query: 110 LHYAASKNRHEIAVML 125
+ A + +IA L
Sbjct: 115 VDLAEEQGHRDIARYL 130
>4GMM-A nrPDB
Length = 612
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Query: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAV---MLLEGGANPDAK 135
IA R EI+ G G N++ C L A+ + E + ML+ G NP+ K
Sbjct: 219 IAHLPDRREIIS--FGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGK 276
Query: 136 DHYEATAMHRAAAKGNLKMIHILL 159
Y A A A K NL M++ L
Sbjct: 277 KKYLAAAFPSACGKTNLAMMNPTL 300
>2NYJ-A nrPDB
Length = 273
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 38/157 (24%)
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAK---DHYEAT-----------AMHRAAAKGN 151
G T LH A + + +L+E GA+ A D ++ T + AA
Sbjct: 101 GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQ 160
Query: 152 LKMIHILL---YYKASTNIQDTEGNTPLHLACD--EERVEEAKLLVSQ-------GASIY 199
L ++ LL + A + +D+ GNT LH + + V+ K + S GA ++
Sbjct: 161 LAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLH 220
Query: 200 -------IENKEEKTPLQVAK-----GGLGLILKRMV 224
I N++ TPL +A G L IL+R +
Sbjct: 221 PTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREI 257
>3I5Q-B nrPDB
Length = 252
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 24/111 (21%)
Query: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH---- 137
SA +DE++K L GK + + + PL Y HEIA+ + + D +DH
Sbjct: 37 SAIKDELIKTLDGKILSTSELFNDFAVPLSY------HEIALFIFKIA---DFRDHEVIM 87
Query: 138 ------YEATAM---HRAAAKGNLKMIHIL--LYYKASTNIQDTEGNTPLH 177
+++ M + + ++ I++L + K N+QD+E P+
Sbjct: 88 AKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIF 138
>3I5P-A nrPDB
Length = 525
Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 24/111 (21%)
Query: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH---- 137
SA +DE++K L GK + + + PL Y HEIA+ + + D +DH
Sbjct: 310 SAIKDELIKTLDGKILSTSELFNDFAVPLSY------HEIALFIFKIA---DFRDHEVIM 360
Query: 138 ------YEATAM---HRAAAKGNLKMIHIL--LYYKASTNIQDTEGNTPLH 177
+++ M + + ++ I++L + K N+QD+E P+
Sbjct: 361 AKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIF 411
>2B0O-E nrPDB
Length = 301
Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 24/71 (33%), Positives = 37/71 (52%)
Query: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
+V+F++Q G ++ K G + LH AA + + +K LL A V VN+ G T L A
Sbjct: 208 LVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIAR 267
Query: 115 SKNRHEIAVML 125
K+ E +L
Sbjct: 268 KKHHKECEELL 278
Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 77 LHIA---ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA 130
LH+A A+ +V ++ G ++A +G T LHYAA N+ + +LL+G A
Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRA 250
Score = 26.6 bits (57), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 19/123 (15%)
Query: 107 CTPLH---YAASKNRHEIAVMLLEGGAN----------PDAKDHYEATAMH---RAAAKG 150
CTP + A NR ++V LE AN PDA+ E +H + A +
Sbjct: 148 CTPEPQRLWTAICNRDLLSV--LEAFANGQDFGQPLPGPDAQAP-EELVLHLAVKVANQA 204
Query: 151 NLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQ 210
+L ++ ++ + + +GNT LH A + + KLL+ A + N+ +T L
Sbjct: 205 SLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALD 264
Query: 211 VAK 213
+A+
Sbjct: 265 IAR 267
>3LVQ-E nrPDB
Length = 497
Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 39/76 (51%)
Query: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
+V+F++Q G ++ K G + LH AA + + +K LL A V VN+ G T L A
Sbjct: 189 LVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIAR 248
Query: 115 SKNRHEIAVMLLEGGA 130
K+ E +L + A
Sbjct: 249 KKHHKECEELLEQAQA 264
>6DVZ-A nrPDB
Length = 791
Score = 32.0 bits (71), Expect = 0.21, Method: Composition-based stats.
Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 27/149 (18%)
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN--------------GCTPLHYAASKNR 118
G + L+IA + +I L+ GA VNA + G TPL AA N+
Sbjct: 215 GQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQ 274
Query: 119 HEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGN--------LKMIHILLYYKAST---- 165
EI +L+E + ++D +H +K ++ ++ ++
Sbjct: 275 PEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELE 334
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+++ +G TPL LA + E K ++S+
Sbjct: 335 TMRNNDGLTPLQLAAKMGKAEILKYILSR 363
>6OO7-A nrPDB
Length = 786
Score = 31.2 bits (69), Expect = 0.43, Method: Composition-based stats.
Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 33/162 (20%)
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HYEATAM 143
AQ G + LH A K + +L+E GAN AK ++ +
Sbjct: 153 AQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPL 212
Query: 144 HRAAAKGNLKMIHILL---YYKASTNIQDTEGNTPLH--LACDEERVEEAKL-------L 191
AA +++ LL + AS QD+ GNT LH + ++ E + L L
Sbjct: 213 SLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGL 272
Query: 192 VSQGASIY-------IENKEEKTPLQV-AKGGLGLILKRMVE 225
+ GA + I N E TPL++ AK G I K +++
Sbjct: 273 LQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQ 314
>6G1K-A nrPDB
Length = 921
Score = 30.0 bits (66), Expect = 0.84, Method: Compositional matrix adjust.
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 12/104 (11%)
Query: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVND-------KDDAGWSPLHI--AASAGRDE 87
D RTAL A + EI+E LL V V D K+ G L + +G +
Sbjct: 67 DPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQ 126
Query: 88 IVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
+ LL K Q + + TP+ AA N +EI ML++ G +
Sbjct: 127 VPPILLDK--QFSDFTPD-ITPIILAAHTNNYEIIKMLVQKGVS 167
>4N5Q-A nrPDB
Length = 257
Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNA----VNQN----------GCTPLHYAASKNR 118
G + L+IA + +I L+ GA VNA V N G TPL AA N+
Sbjct: 99 GQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQ 158
Query: 119 HEIAVMLLEGG----ANPDAKD----HYEATAMHRAAAKGNL--KMIHILLYYKAS---T 165
EI +L+E + D++ H T + + +M ++L +
Sbjct: 159 PEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELE 218
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+++ +G TPL LA + E K ++S+
Sbjct: 219 TMRNNDGLTPLQLAAKMGKAEILKYILSR 247
>6C8G-A nrPDB
Length = 675
Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 45/176 (25%), Positives = 68/176 (38%), Gaps = 40/176 (22%)
Query: 65 PVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVM 124
P D G + LHIA V+ L+ KGA V+A + + K+
Sbjct: 95 PFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARG-----RFFQPKD------- 142
Query: 125 LLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILL---YYKASTNIQDTEGNTPLH--LA 179
EGG ++ + AA ++H L + KA QD+ GNT LH +A
Sbjct: 143 --EGGYF-----YFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVA 195
Query: 180 CDEERVEEAK-------LLVSQGASIY-------IENKEEKTPLQVAK--GGLGLI 219
+ E K LLV + +Y I N + +PL +A G +G+
Sbjct: 196 IADNTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIF 251
>6BBJ-A nrPDB
Length = 868
Score = 28.1 bits (61), Expect = 3.5, Method: Composition-based stats.
Identities = 45/178 (25%), Positives = 61/178 (34%), Gaps = 60/178 (33%)
Query: 65 PVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN--------------GCTPL 110
P D G + LHIA V+ L+ KGA V+A + G PL
Sbjct: 226 PFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPL 285
Query: 111 HYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT 170
AA N+ +I HY H+ KA QD+
Sbjct: 286 SLAACTNQPDIV--------------HYLTENAHK----------------KADIRRQDS 315
Query: 171 EGNTPLH--LACDEERVEEAK-------LLVSQGASIY-------IENKEEKTPLQVA 212
GNT LH +A + E K LLV + +Y I N + +PL +A
Sbjct: 316 RGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMA 373
>6BO5-A nrPDB
Length = 695
Score = 27.7 bits (60), Expect = 3.9, Method: Composition-based stats.
Identities = 10/30 (33%), Positives = 21/30 (70%)
Query: 171 EGNTPLHLACDEERVEEAKLLVSQGASIYI 200
+G++ LH+A ++ ++ KLLV GA +++
Sbjct: 123 QGHSALHIAIEKRSLQCVKLLVENGADVHL 152
>5HI9-A nrPDB
Length = 770
Score = 27.7 bits (60), Expect = 3.9, Method: Composition-based stats.
Identities = 10/30 (33%), Positives = 21/30 (70%)
Query: 171 EGNTPLHLACDEERVEEAKLLVSQGASIYI 200
+G++ LH+A ++ ++ KLLV GA +++
Sbjct: 163 QGHSALHIAIEKRSLQCVKLLVENGADVHL 192
>5AN8-A nrPDB
Length = 613
Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 16/97 (16%)
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK-------------DHYEATAM 143
AQ G + LH A K + +L+E GAN AK ++ +
Sbjct: 78 AQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPL 137
Query: 144 HRAAAKGNLKMIHILL---YYKASTNIQDTEGNTPLH 177
AA +++ LL + AS QD+ GNT LH
Sbjct: 138 SLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLH 174
>2ZCI-A nrPDB
Length = 610
Score = 27.7 bits (60), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 94 GKGAQVNAVNQNGCTPLHYAASKNRHEIAV---MLLEGGANPDAKDHYEATAMHRAAAKG 150
G G NA+ C L A+ R E + ML+ NP+ K ++ A A A K
Sbjct: 218 GSGYGGNAILAKKCYALRIASVMAREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKT 277
Query: 151 NLKMI 155
NL MI
Sbjct: 278 NLAMI 282
>3W9G-A nrPDB
Length = 260
Score = 26.9 bits (58), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 46/175 (26%), Positives = 65/175 (37%), Gaps = 44/175 (25%)
Query: 49 SAGHTEIVEFLLQLG-----------VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA 97
SAG + + LL + P D G + LHIA V+ L+ KGA
Sbjct: 58 SAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGA 117
Query: 98 QVNAVNQN--------------GCTPLHYAASKNRHEIAVMLLEGG---ANPDAKDHYEA 140
V+A + G PL AA N+ I L E G A+ +D
Sbjct: 118 DVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGN 177
Query: 141 TAMH---------RAAAKGNLKMIHILLYYKA----STNIQ---DTEGNTPLHLA 179
T +H R K KM +LL A TN++ + +G +PL +A
Sbjct: 178 TVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMA 232
>6HEG-A nrPDB
Length = 809
Score = 26.6 bits (57), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 9/58 (15%)
Query: 78 HIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
IA G+D + G GA ++A + A S++ IA +LL+G A+PDA+
Sbjct: 499 RIARRRGQDGRYQLANGMGAMLDAND---------ALSRHEWLIAPLLLQGSASPDAR 547
>6MHW-A nrPDB
Length = 826
Score = 26.6 bits (57), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 18/119 (15%)
Query: 94 GKGAQVNAVNQN-----GCTPLHYAASKNRHEIAVMLLE-GGANPDAKD-------HYEA 140
KGA N Q+ G TPL AA N+ EI +L+E + ++D H
Sbjct: 246 AKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALV 305
Query: 141 TAMHRAAAKGNL--KMIHILLYYKASTNIQDTEGN---TPLHLACDEERVEEAKLLVSQ 194
T + + +M ++L + ++ T N TPL LA + E K ++S+
Sbjct: 306 TVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
4NIK-A nrPDB 283 4e-77
2DWZ-A nrPDB 283 5e-77
6BY9-A nrPDB 207 3e-54
3B7B-A nrPDB 202 8e-53
5AQ9-A nrPDB 190 3e-49
6AUN-A nrPDB 190 5e-49
5AQB-A nrPDB 188 2e-48
4OAU-C nrPDB 187 5e-48
5JHQ-A nrPDB 185 1e-47
6MWQ-A nrPDB 185 2e-47
5AQA-A nrPDB 185 2e-47
5MIO-C nrPDB 184 4e-47
5AQ7-A nrPDB 182 1e-46
6FES-A nrPDB 181 2e-46
1WG0-A nrPDB 179 7e-46
5H76-A nrPDB 170 5e-43
5HKP-A nrPDB 169 1e-42
3ZKJ-A nrPDB 163 5e-41
4O1O-A nrPDB 161 2e-40
5ET1-A nrPDB 159 8e-40
3EU9-A nrPDB 157 5e-39
4OT9-A nrPDB 152 8e-38
5CBO-A nrPDB 143 4e-35
4Z68-A nrPDB 143 6e-35
5GP7-A nrPDB 134 3e-32
6EMK-G nrPDB 131 3e-31
3LJN-A nrPDB 126 1e-29
6BOA-A nrPDB 120 6e-28
5D68-A nrPDB 117 3e-27
5DND-A nrPDB 116 9e-27
6E2G-A nrPDB 115 2e-26
1BLX-B nrPDB 110 6e-25
1BD8-A nrPDB 108 3e-24
6DMR-A nrPDB 102 1e-22
4BSZ-B nrPDB 100 5e-22
5UIL-A nrPDB 99 1e-21
1G3N-B nrPDB 97 6e-21
3UI2-A nrPDB 97 6e-21
3DEO-A nrPDB 96 1e-20
2KXP-C nrPDB 95 2e-20
3T9K-A nrPDB 94 4e-20
3EHQ-A nrPDB 88 3e-18
5UQE-A nrPDB 87 5e-18
5U0K-A nrPDB 87 8e-18
5U0J-A nrPDB 83 1e-16
4XD0-A nrPDB 83 1e-16
1DCQ-A nrPDB 78 3e-15
Sequences not found previously or not previously below threshold:
2RFA-A nrPDB 103 6e-23
5AN8-A nrPDB 77 7e-15
6OO7-A nrPDB 76 1e-14
1D9S-A nrPDB 75 3e-14
5IRX-A nrPDB 72 2e-13
6DVZ-A nrPDB 71 3e-13
2A5E-A nrPDB 71 5e-13
6BO5-A nrPDB 70 6e-13
5HI9-A nrPDB 70 6e-13
2F37-A nrPDB 68 3e-12
2NYJ-A nrPDB 67 5e-12
4N5Q-A nrPDB 67 1e-11
2ETB-A nrPDB 65 2e-11
6CV9-A nrPDB 65 3e-11
3LVQ-E nrPDB 64 5e-11
6CUD-A nrPDB 63 1e-10
2B0O-E nrPDB 62 2e-10
6C8G-A nrPDB 62 3e-10
6BBJ-A nrPDB 62 3e-10
6MHW-A nrPDB 60 8e-10
4DX2-A nrPDB 59 1e-09
6DJS-A nrPDB 59 2e-09
3W9G-A nrPDB 59 2e-09
6G1K-A nrPDB 58 3e-09
4CJ9-A nrPDB 44 6e-05
5Z96-A nrPDB 43 7e-05
6BWI-A nrPDB 36 0.010
1EV4-A nrPDB 30 1.1
2DI3-A nrPDB 29 1.7
6GC1-A nrPDB 28 4.8
3WQO-A nrPDB 27 6.3
>4NIK-A nrPDB
Length = 230
Score = 283 bits (725), Expect = 4e-77, Method: Composition-based stats.
Identities = 226/226 (100%), Positives = 226/226 (100%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL
Sbjct: 5 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 64
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE 120
QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE
Sbjct: 65 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE 124
Query: 121 IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC 180
IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC
Sbjct: 125 IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC 184
Query: 181 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG
Sbjct: 185 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 230
>2DWZ-A nrPDB
Length = 231
Score = 283 bits (723), Expect = 5e-77, Method: Composition-based stats.
Identities = 213/226 (94%), Positives = 221/226 (97%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
MEGCVSN+M+CNLAYSGKL+ELKE ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL
Sbjct: 1 MEGCVSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHE 120
QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALL KGA VNAVNQNGCTPLHYAASKNRHE
Sbjct: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHE 120
Query: 121 IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLAC 180
IAVMLLEGGANPDAKDHY+ATAMHRAAAKGNLKM+HILL+YKASTNIQDTEGNTPLHLAC
Sbjct: 121 IAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLAC 180
Query: 181 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
DEERVEEAK LV+QGASIYIENKEEKTPLQVAKGGLGLILKR+ EG
Sbjct: 181 DEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAEG 226
>6BY9-A nrPDB
Length = 328
Score = 207 bits (527), Expect = 3e-54, Method: Composition-based stats.
Identities = 64/213 (30%), Positives = 109/213 (51%), Gaps = 2/213 (0%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
ME + A +G ++ + ++ + +D RT L A H E V++L+
Sbjct: 97 MEHQNKRSPLHAAAEAGHVD-ICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLI 155
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAASKNRH 119
+ G V+ KD G + LH+AA G E+V+ LL G VN + G TP+ +A
Sbjct: 156 KAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHV 215
Query: 120 EIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
++ +LL G++ + +D+ E +H AA G + + ILL K + + G++PLH+A
Sbjct: 216 DLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIA 275
Query: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
E R + L +S+ + + ++NKE +TPLQ A
Sbjct: 276 ARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 308
Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats.
Identities = 58/202 (28%), Positives = 98/202 (48%), Gaps = 2/202 (0%)
Query: 14 AYSGKLEELKESILADKSLATRTD-QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
A G+L+++ ++ + + Q+ R+ LH A AGH +I L+Q G ++ +
Sbjct: 75 ARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSED 134
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG-AN 131
+PL AA E VK L+ GA V+ + G T LH AA K +E+ LL G +
Sbjct: 135 QRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMD 194
Query: 132 PDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
+ +D T M A ++ ++ +LL + NI+D E N LH A V+ A++L
Sbjct: 195 VNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEIL 254
Query: 192 VSQGASIYIENKEEKTPLQVAK 213
++ ++ N +PL +A
Sbjct: 255 LAAKCDLHAVNIHGDSPLHIAA 276
Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats.
Identities = 52/178 (29%), Positives = 87/178 (48%), Gaps = 2/178 (1%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVN 67
+ A + LE +K ++ +L D + T LH A GH E+V++LL G + VN
Sbjct: 138 PLMEAAENNHLEAVK-YLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 196
Query: 68 DKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE 127
+DD GW+P+ A ++VK LL KG+ +N + LH+AA +IA +LL
Sbjct: 197 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 256
Query: 128 GGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV 185
+ A + + + +H AA + + + L + +++ EG TPL A +V
Sbjct: 257 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQV 314
Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats.
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 3/208 (1%)
Query: 20 EELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK--DDAGWSPL 77
E L+ +++A S + + L+++ G + V +L G+ N K SPL
Sbjct: 47 ETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPL 106
Query: 78 HIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH 137
H AA AG +I L+ GA ++ +++ TPL AA N E L++ GA D KD
Sbjct: 107 HAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA 166
Query: 138 YEATAMHRAAAKGNLKMIHILLYYKA-STNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+T +H AA KG+ +++ LL N QD G TP+ A + + V+ KLL+S+G+
Sbjct: 167 EGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 226
Query: 197 SIYIENKEEKTPLQVAKGGLGLILKRMV 224
I I + EE L A + + ++
Sbjct: 227 DINIRDNEENICLHWAAFSGCVDIAEIL 254
>3B7B-A nrPDB
Length = 237
Score = 202 bits (515), Expect = 8e-53, Method: Composition-based stats.
Identities = 64/213 (30%), Positives = 109/213 (51%), Gaps = 2/213 (0%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
ME + A +G ++ + ++ + +D RT L A H E V++L+
Sbjct: 6 MEHQNKRSPLHAAAEAGHVD-ICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLI 64
Query: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAASKNRH 119
+ G V+ KD G + LH+AA G E+V+ LL G VN + G TP+ +A
Sbjct: 65 KAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHV 124
Query: 120 EIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
++ +LL G++ + +D+ E +H AA G + + ILL K + + G++PLH+A
Sbjct: 125 DLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIA 184
Query: 180 CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
E R + L +S+ + + ++NKE +TPLQ A
Sbjct: 185 ARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 217
Score = 148 bits (373), Expect = 2e-36, Method: Composition-based stats.
Identities = 52/178 (29%), Positives = 87/178 (48%), Gaps = 2/178 (1%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVN 67
+ A + LE +K ++ +L D + T LH A GH E+V++LL G + VN
Sbjct: 47 PLMEAAENNHLEAVK-YLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 105
Query: 68 DKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE 127
+DD GW+P+ A ++VK LL KG+ +N + LH+AA +IA +LL
Sbjct: 106 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 165
Query: 128 GGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV 185
+ A + + + +H AA + + + L + +++ EG TPL A +V
Sbjct: 166 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQV 223
Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats.
Identities = 52/152 (34%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
SPLH AA AG +I L+ GA ++ +++ TPL AA N E L++ GA D
Sbjct: 12 RSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVD 71
Query: 134 AKDHYEATAMHRAAAKGNLKMIHILLYYKA-STNIQDTEGNTPLHLACDEERVEEAKLLV 192
KD +T +H AA KG+ +++ LL N QD G TP+ A + + V+ KLL+
Sbjct: 72 PKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLL 131
Query: 193 SQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
S+G+ I I + EE L A + + ++
Sbjct: 132 SKGSDINIRDNEENICLHWAAFSGCVDIAEIL 163
Score = 95.8 bits (237), Expect = 1e-20, Method: Composition-based stats.
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 1/122 (0%)
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
QN +PLH AA +I ML++ GAN D + T + AA +L+ + L+ A
Sbjct: 9 QNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGA 68
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLLVSQGA-SIYIENKEEKTPLQVAKGGLGLILKR 222
+ +D EG+T LHLA + E + L+S G + ++ TP+ A + L +
Sbjct: 69 LVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVK 128
Query: 223 MV 224
++
Sbjct: 129 LL 130
Score = 43.0 bits (100), Expect = 9e-05, Method: Composition-based stats.
Identities = 14/48 (29%), Positives = 26/48 (54%)
Query: 167 IQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKG 214
++ +PLH A + V+ +LV GA+I +++++TPL A
Sbjct: 6 MEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAE 53
>5AQ9-A nrPDB
Length = 422
Score = 190 bits (484), Expect = 3e-49, Method: Composition-based stats.
Identities = 56/149 (37%), Positives = 85/149 (57%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ L+ GA VNA + G TPLH AA EI +LL+ GA+ DA D
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 77
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+ T +H AA G+L+++ +LL A N D++G TPLHLA +E ++L+ GA
Sbjct: 78 VFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA 137
Query: 197 SIYIENKEEKTPLQVAKGGLGLILKRMVE 225
+ ++K KTP +A + +++
Sbjct: 138 DVNAQDKFGKTPFDLADDNGNDDVGTLLQ 166
Score = 183 bits (465), Expect = 4e-47, Method: Composition-based stats.
Identities = 63/155 (40%), Positives = 84/155 (54%), Gaps = 1/155 (0%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V L+ G VN D+ G +PLH+AA +G EIV+ LL GA V+A +
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 77
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
G TPLH AA EI +LL+ GA+ +A D T +H AA G L+++ +LL + A
Sbjct: 78 VFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA 137
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLL-VSQGAS 197
N QD G TP LA D + LL V+ A
Sbjct: 138 DVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAAD 172
Score = 176 bits (447), Expect = 6e-45, Method: Composition-based stats.
Identities = 57/149 (38%), Positives = 85/149 (57%), Gaps = 1/149 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ ++A+ + D T LH A +GH EIVE LL+ G V+
Sbjct: 18 LLEAARAGQDDEVR-ILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 76
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G++PLH+AA G EIV+ LL GA VNA++ +G TPLH AA EI +LL+ G
Sbjct: 77 DVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHG 136
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
A+ +A+D + T A GN + +L
Sbjct: 137 ADVNAQDKFGKTPFDLADDNGNDDVGTLL 165
Score = 123 bits (310), Expect = 5e-29, Method: Composition-based stats.
Identities = 48/137 (35%), Positives = 63/137 (45%), Gaps = 1/137 (0%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ AYSG L E+ E +L + +D T LH A GH EIVE LL+ G VN
Sbjct: 50 PLHLAAYSGHL-EIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNA 108
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG 128
D G +PLH+AA G EIV+ LL GA VNA ++ G TP A ++ +L
Sbjct: 109 MDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVA 168
Query: 129 GANPDAKDHYEATAMHR 145
A +
Sbjct: 169 AAADQLGARVGYIELDL 185
>6AUN-A nrPDB
Length = 752
Score = 190 bits (482), Expect = 5e-49, Method: Composition-based stats.
Identities = 66/253 (26%), Positives = 106/253 (41%), Gaps = 41/253 (16%)
Query: 2 EGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ 61
EGC + C S L EL + A + TD TA H+A ++++++ L +
Sbjct: 151 EGCTPLHLACRKGDSEILVELVQYCHAQMDV---TDNKGETAFHYAVQGDNSQVLQLLGK 207
Query: 62 LG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGC------------- 107
+N + G +PLH+A G+ E+V+ LL A+ N + +G
Sbjct: 208 NASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGC 267
Query: 108 ---------------------TPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRA 146
+PLH+A E+A MLL+ G + D+ TA+H A
Sbjct: 268 AEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALHVA 324
Query: 147 AAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEK 206
+ + +LL Y A+ GNTPLHLA ++ +E K L+ GA + N +
Sbjct: 325 VMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGE 384
Query: 207 TPLQVAKGGLGLI 219
TP +A +
Sbjct: 385 TPAFMASKISKQL 397
Score = 91.6 bits (226), Expect = 2e-19, Method: Composition-based stats.
Identities = 45/163 (27%), Positives = 69/163 (42%), Gaps = 8/163 (4%)
Query: 52 HTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLH 111
H E+++ L + + W+ H+A G E + N+ GCTPLH
Sbjct: 103 HVEVLQHL----SDL-IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLH 157
Query: 112 YAASKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQD 169
A K EI V L++ A D D+ TA H A N +++ +L A N +
Sbjct: 158 LACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVN 217
Query: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
+G TPLHLAC + E ++L+ A + P+ A
Sbjct: 218 KQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGF-PIHTA 259
Score = 70.8 bits (172), Expect = 5e-13, Method: Composition-based stats.
Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 2/120 (1%)
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY-KAST 165
T H A E ++ T +H A KG+ +++ L+ Y A
Sbjct: 120 WTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQYCHAQM 179
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQVAKGGLGLILKRMV 224
++ D +G T H A + + +LL A + NK+ TPL +A + R++
Sbjct: 180 DVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGKQEMVRVL 239
Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats.
Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 2/100 (2%)
Query: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV 185
L+ ++ + H T H A G + H + + ++ EG TPLHLAC +
Sbjct: 107 LQHLSDL-IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDS 165
Query: 186 EEAKLLVSQ-GASIYIENKEEKTPLQVAKGGLGLILKRMV 224
E LV A + + + + +T A G + +++
Sbjct: 166 EILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLL 205
>5AQB-A nrPDB
Length = 428
Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats.
Identities = 62/159 (38%), Positives = 87/159 (54%), Gaps = 1/159 (0%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + L+ G VN D+ GW+PLH+AA G EIV+ LL GA VNA +
Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADVNAAD 76
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
+G TPLH AA EI +LL+ GA+ +A D T +H AA G+L+++ +LL A
Sbjct: 77 IDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGA 136
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202
N QD G TP LA D + A++L + +++
Sbjct: 137 DVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKD 175
Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats.
Identities = 55/148 (37%), Positives = 82/148 (55%), Gaps = 1/148 (0%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ + L+ GA VNA+++ G TPLH AA EI LL+ GA+ +A D
Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADVNAAD 76
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
T +H AA G+L+++ +LL Y A N D G TPLHLA +E ++L+ GA
Sbjct: 77 IDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGA 136
Query: 197 SIYIENKEEKTPLQVAKGGLGLILKRMV 224
+ ++K KTP +A + ++
Sbjct: 137 DVNAQDKFGKTPRDLAIDNGNEDIAEVL 164
Score = 170 bits (432), Expect = 3e-43, Method: Composition-based stats.
Identities = 72/219 (32%), Positives = 106/219 (48%), Gaps = 11/219 (5%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E + ++A+ + D+ T LH A GH EIVE LL+ G VN
Sbjct: 18 LLEAARAGQDDECR-ILMANGADVNALDEVGWTPLHLAA-WGHLEIVECLLKNGADVNAA 75
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G++PLH+AA +G EIV+ LL GA VNA +Q G TPLH AA EI +LL+ G
Sbjct: 76 DIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNG 135
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAK 189
A+ +A+D + T A GN + +L ++D L +
Sbjct: 136 ADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAADQ----LGARVGY---IE 188
Query: 190 LLVSQGASIYIENKEEKTPLQVAKGGL--GLILKRMVEG 226
L ++ G + EE+ P+ L G IL R+ G
Sbjct: 189 LDLNSGKILESFRSEERFPMMSTFKVLLAGAILSRIDAG 227
>4OAU-C nrPDB
Length = 699
Score = 187 bits (474), Expect = 5e-48, Method: Composition-based stats.
Identities = 64/236 (27%), Positives = 108/236 (45%), Gaps = 18/236 (7%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66
N ++ + ++ +++ + ++ + ++ T LH A +IVE LL+ G
Sbjct: 6 NHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADP 65
Query: 67 NDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 126
+ G +P +AA AG +++K L KGA VN + G T AA + + L
Sbjct: 66 VLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLY 125
Query: 127 EGGANPDAKDHY----------EATAMHRAAAKGNLKMIHILL-YYKASTNIQDTEGNTP 175
+ GAN + + ATA+ AA KG+++++ ILL A N D G
Sbjct: 126 KRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNA 185
Query: 176 LHLAC----DEERVEEAKLLVSQGASIYIENKEEKTPLQVA--KGGLGLILKRMVE 225
L A D + LL+ GA + + + KTPL +A K LGL+ +R++E
Sbjct: 186 LIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLV-QRLLE 240
Score = 131 bits (330), Expect = 2e-31, Method: Composition-based stats.
Identities = 55/210 (26%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
A +G + +L + L+ + D TA A G + ++FL + G VN
Sbjct: 75 PFILAAIAGSV-KLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNL 133
Query: 69 KDD----------AGWSPLHIAASAGRDEIVKALLGK-GAQVNAVNQNGCTPLHYAASKN 117
+ G + L AA G E++K LL + GA VNA + G L +A +
Sbjct: 134 RRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSS 193
Query: 118 RHE----IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK-ASTNIQDTEG 172
I +LL+ GA+ + + T + A K +L ++ LL + N D++G
Sbjct: 194 DDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDG 253
Query: 173 NTPLHLACDEERVEEAKLLVSQGASIYIEN 202
T L LA + + + A+LL +GAS +
Sbjct: 254 KTALLLAVELKLKKIAELLCKRGASTDCGD 283
Score = 105 bits (263), Expect = 1e-23, Method: Composition-based stats.
Identities = 56/203 (27%), Positives = 81/203 (39%), Gaps = 22/203 (10%)
Query: 10 VCNLAYSGKLEELKESILADKSLAT-----RTDQD-----SRTALHWACSAGHTEIVEFL 59
A GK++ LK + + + DQ+ TAL A GH E+++ L
Sbjct: 109 FMEAAVYGKVKALK-FLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKIL 167
Query: 60 L-QLGVPVNDKDDAGWSPLHIAASAGRDEIVK----ALLGKGAQVNAVNQNGCTPLHYAA 114
L ++G VN D+ G + L A + D V+ LL GA VN + G TPL A
Sbjct: 168 LDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAV 227
Query: 115 SKNRHEIAVMLLEGGA-NPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
K + LLE + D TA+ A K+ +L AST+ D
Sbjct: 228 EKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDL--- 284
Query: 174 TPLHLACDEERVEEAKLLVSQGA 196
+ A K+L+S GA
Sbjct: 285 --VMTARRNYDHSLVKVLLSHGA 305
Score = 71.9 bits (175), Expect = 2e-13, Method: Composition-based stats.
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 139 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTE-GNTPLHLACDEERVEEAKLLVSQGAS 197
+ + +A ++ ++ LL A+ N Q+ E G TPLH A R + +LL+ GA
Sbjct: 5 DNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGAD 64
Query: 198 IYIENKEEKTPLQVA--KGGLGLILKRMVEG 226
+ K TP +A G + L+ + +G
Sbjct: 65 PVLRKKNGATPFILAAIAGSVKLLKLFLSKG 95
Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats.
Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 8/96 (8%)
Query: 3 GCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQL 62
G ++ + G ++ + + TD D +TAL A +I E L +
Sbjct: 219 GKTPLILAVEKKHLGL---VQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKR 275
Query: 63 GVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
G + D + A +VK LL GA+
Sbjct: 276 GASTDCGD-----LVMTARRNYDHSLVKVLLSHGAK 306
>5JHQ-A nrPDB
Length = 482
Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats.
Identities = 69/226 (30%), Positives = 109/226 (48%), Gaps = 25/226 (11%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVN 67
+ +G + +K L D + D R + LH+A G ++VE LLQ+G V+
Sbjct: 19 LLEACRNGDVSRVKR--LVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVH 76
Query: 68 DKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE 127
+DD G PLH A S G E+V LL +GA NA + TPLH AA K + ++ ++LL+
Sbjct: 77 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 136
Query: 128 GGANPDAKDHYEATAMHR--------------------AAAKGNLK-MIHILLYYKASTN 166
GA+P+ ++ +A+ AA GN + ++ +L + +
Sbjct: 137 HGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCH 196
Query: 167 IQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
D +TPLHLA RV +LL+ GA ++ ++K PL A
Sbjct: 197 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNA 242
Score = 169 bits (429), Expect = 8e-43, Method: Composition-based stats.
Identities = 71/239 (29%), Positives = 106/239 (44%), Gaps = 24/239 (10%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A SG E+L + +D T LH A IV+ LLQ G V+ K
Sbjct: 172 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 231
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G PLH A S G E+ + LL GA VNA++ TPLH AASKNR E+ +LL G
Sbjct: 232 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 291
Query: 130 ANPDAKD---------------------HYEATAMHRAAAKGNLKMIHILLYYKASTNIQ 168
A+P + ++ ++ +AA + +L + L + Q
Sbjct: 292 ADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQ 351
Query: 169 DTEGNTPLHLA---CDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
T LH A +R + +LL+ +GA++ +NK+ TPL VA + ++
Sbjct: 352 PQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL 410
Score = 136 bits (343), Expect = 7e-33, Method: Composition-based stats.
Identities = 65/204 (31%), Positives = 98/204 (48%), Gaps = 24/204 (11%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGW--SPLHIAASAGRDEIVKALLGKGAQVNA 101
L AC G V+ L+ VN KD AG SPLH AA GR ++V+ LL GA V+A
Sbjct: 19 LLEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHA 77
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
+ G PLH A S E+ +LL GA+P+A+D++ T +H AA KG + + +LL +
Sbjct: 78 RDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH 137
Query: 162 KASTNIQDTEGNTPLHLA--------------------CDEERVE-EAKLLVSQGASIYI 200
A NI++T+G + L LA E LL + +
Sbjct: 138 GADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHA 197
Query: 201 ENKEEKTPLQVAKGGLGLILKRMV 224
+ + TPL +A G + + +++
Sbjct: 198 SDGRKSTPLHLAAGYNRVRIVQLL 221
Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats.
Identities = 57/240 (23%), Positives = 87/240 (36%), Gaps = 25/240 (10%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66
+ + N G E+ E +L + D T LH A S E+ LL G
Sbjct: 236 LVPLHNACSYGHY-EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 294
Query: 67 NDKDDAGWSP---------------------LHIAASAGRDEIVKALLGKGAQVNAVNQN 105
+ G S L AA VK L Q+
Sbjct: 295 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 354
Query: 106 GCTPLHYAASKNRHE---IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK 162
T LH A + + + +LL GAN + K+ T +H AA + + ++ +L +
Sbjct: 355 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 414
Query: 163 ASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKR 222
A N DT G T LH A ++ +LL+S G+ I + + T Q+ + IL
Sbjct: 415 AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSE 474
>6MWQ-A nrPDB
Length = 493
Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats.
Identities = 58/148 (39%), Positives = 81/148 (54%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V L+ G VN D G +PLH+AA G EIV+ LL GA VNA +
Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAAD 68
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
G TPLH AA+ EI +LL+ GA+ +A D T +H A G+L+++ +LL + A
Sbjct: 69 LWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGA 128
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLL 191
N QD G T ++ D + A++L
Sbjct: 129 DVNAQDKFGKTAFDISIDNGNEDLAEIL 156
Score = 179 bits (455), Expect = 6e-46, Method: Composition-based stats.
Identities = 54/149 (36%), Positives = 86/149 (57%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ L+ GA VNA+++ G TPLH AA + EI +LL+ GA+ +A D
Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAAD 68
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+ T +H AA G+L+++ +LL Y A N D G TPLHL + +E ++L+ GA
Sbjct: 69 LWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGA 128
Query: 197 SIYIENKEEKTPLQVAKGGLGLILKRMVE 225
+ ++K KT ++ L +++
Sbjct: 129 DVNAQDKFGKTAFDISIDNGNEDLAEILQ 157
Score = 173 bits (438), Expect = 7e-44, Method: Composition-based stats.
Identities = 72/209 (34%), Positives = 103/209 (49%), Gaps = 9/209 (4%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ ++A+ + D+ T LH A GH EIVE LL+ G VN
Sbjct: 9 LLEAARAGQDDEVR-ILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAA 67
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G +PLH+AA+AG EIV+ LL GA VNA++ G TPLH A EI +LL+ G
Sbjct: 68 DLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHG 127
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK-ASTNIQ---DTEGNTPLHLACDEERV 185
A+ +A+D + TA + GN + IL + + +G LA DE
Sbjct: 128 ADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDIAHRIVAPGKGI----LAADESTG 183
Query: 186 EEAKLLVSQGASIYIENKEEKTPLQVAKG 214
AK L S G EN+ L +
Sbjct: 184 SIAKRLQSIGTENTEENRRFYRQLLLTAD 212
>5AQA-A nrPDB
Length = 418
Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats.
Identities = 56/138 (40%), Positives = 80/138 (57%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ L+ GA VNA + G TPLH AA EI +LL+ GA+ DA D
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 77
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+ T +H AA G+L+++ +LL A N D++G TPLHLA E ++L+ GA
Sbjct: 78 VFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGA 137
Query: 197 SIYIENKEEKTPLQVAKG 214
+ ++K K PL +A
Sbjct: 138 DVDAQDKFGKRPLWLAAD 155
Score = 183 bits (464), Expect = 6e-47, Method: Composition-based stats.
Identities = 61/151 (40%), Positives = 82/151 (54%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V L+ G VN D+ G +PLH+AA +G EIV+ LL GA V+A +
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 77
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
G TPLH AA EI +LL+ GA+ +A D T +H AA G +++ +LL A
Sbjct: 78 VFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAGA 137
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ QD G PL LA D+ E A LV+
Sbjct: 138 DVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168
Score = 175 bits (445), Expect = 9e-45, Method: Composition-based stats.
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 1/153 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ ++A+ + D T LH A +GH EIVE LL+ G V+
Sbjct: 18 LLEAARAGQDDEVR-ILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 76
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G++PLH+AA G EIV+ LL GA VNA++ +G TPLH AA EI +LL+ G
Sbjct: 77 DVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLKAG 136
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK 162
A+ DA+D + + AA +G+ ++ L+ +
Sbjct: 137 ADVDAQDKFGKRPLWLAADQGHAEIAAKLVAAR 169
Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats.
Identities = 10/46 (21%), Positives = 22/46 (47%)
Query: 179 ACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
A + +E ++L++ GA + + TPL +A L + ++
Sbjct: 21 AARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVL 66
>5MIO-C nrPDB
Length = 573
Score = 184 bits (466), Expect = 4e-47, Method: Composition-based stats.
Identities = 58/148 (39%), Positives = 81/148 (54%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V L+ G VN D +G +PLH+AA+ G EIV+ LL GA V+A +
Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASD 473
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
G TPLH AA EI +LL+ GA+ +A D + T + AA G+LK++ LL + A
Sbjct: 474 LMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGA 533
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLL 191
N QD G T + D + A++L
Sbjct: 534 DVNAQDKFGKTAYDTSIDNGSEDLAEIL 561
Score = 172 bits (437), Expect = 9e-44, Method: Composition-based stats.
Identities = 53/149 (35%), Positives = 83/149 (55%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ L+ GA VNA + +G TPLH AA+ EI +LL+ GA+ A D
Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASD 473
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+T +H AA G+L+++ +LL + A N DT G+TPL LA ++ + L+ GA
Sbjct: 474 LMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGA 533
Query: 197 SIYIENKEEKTPLQVAKGGLGLILKRMVE 225
+ ++K KT + L +++
Sbjct: 534 DVNAQDKFGKTAYDTSIDNGSEDLAEILQ 562
Score = 170 bits (432), Expect = 3e-43, Method: Composition-based stats.
Identities = 57/149 (38%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ ++A+ + TD T LH A + GH EIVE LL+ G V+
Sbjct: 414 LLEAARAGQDDEVR-VLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSAS 472
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G +PLH+AA G EIV+ LL GA VNAV+ G TPL AA +I LL+ G
Sbjct: 473 DLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHG 532
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
A+ +A+D + TA + G+ + IL
Sbjct: 533 ADVNAQDKFGKTAYDTSIDNGSEDLAEIL 561
>5AQ7-A nrPDB
Length = 418
Score = 182 bits (461), Expect = 1e-46, Method: Composition-based stats.
Identities = 61/151 (40%), Positives = 80/151 (52%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V LL G VN D+ G++PLH+AA G IV+ LL GA VNA +
Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 77
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
+ G TPLH AA EI +LL+ GA +A D +H AA G +++ +LL A
Sbjct: 78 ERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGA 137
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ QD G PL LA D+ E A LV+
Sbjct: 138 DVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168
Score = 170 bits (431), Expect = 4e-43, Method: Composition-based stats.
Identities = 53/138 (38%), Positives = 76/138 (55%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ LL GA VN ++ G TPLH AA + I +LL+ GA+ +A D
Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 77
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
T +H AA G+L+++ +LL A N D G PLHLA E ++L+ GA
Sbjct: 78 ERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAGA 137
Query: 197 SIYIENKEEKTPLQVAKG 214
+ ++K K PL +A
Sbjct: 138 DVDAQDKFGKRPLWLAAD 155
Score = 163 bits (412), Expect = 6e-41, Method: Composition-based stats.
Identities = 57/153 (37%), Positives = 85/153 (55%), Gaps = 1/153 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ +LA+ + D+ T LH A GH IVE LL+ G VN
Sbjct: 18 LLEAARAGQDDEVR-ILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAN 76
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D+ G +PLH+AA G EIV+ LL GA VNA + G PLH AA EI +LL+ G
Sbjct: 77 DERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLKAG 136
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK 162
A+ DA+D + + AA +G+ ++ L+ +
Sbjct: 137 ADVDAQDKFGKRPLWLAADQGHAEIAAKLVAAR 169
Score = 82.3 bits (202), Expect = 2e-16, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 38/82 (46%)
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202
+ AA G + ILL A N D G TPLHLA E + ++L+ GA + +
Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 77
Query: 203 KEEKTPLQVAKGGLGLILKRMV 224
+ TPL +A L + ++
Sbjct: 78 ERGHTPLHLAAYTGHLEIVEVL 99
>6FES-A nrPDB
Length = 367
Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats.
Identities = 59/147 (40%), Positives = 77/147 (52%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V LL G VN D+ G++PLH+AA G IV+ LL GA VNA +
Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 69
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
+ G TPLH AA EI +LL+ GA +A D +H AA G+ +++ +LL A
Sbjct: 70 ERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGA 129
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKL 190
QD G TP LA D A+L
Sbjct: 130 DARAQDKFGKTPEDLARDNGYESVARL 156
Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats.
Identities = 53/138 (38%), Positives = 76/138 (55%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ LL GA VN ++ G TPLH AA + I +LL+ GA+ +A D
Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 69
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
T +H AA G+L+++ +LL A N D G PLHLA E ++L+ GA
Sbjct: 70 ERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGA 129
Query: 197 SIYIENKEEKTPLQVAKG 214
++K KTP +A+
Sbjct: 130 DARAQDKFGKTPEDLARD 147
Score = 159 bits (403), Expect = 8e-40, Method: Composition-based stats.
Identities = 55/148 (37%), Positives = 78/148 (52%), Gaps = 1/148 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ +LA+ + D+ T LH A GH IVE LL+ G VN
Sbjct: 10 LLEAARAGQDDEVR-ILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAN 68
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D+ G +PLH+AA G EIV+ LL GA VNA + G PLH AA EI +LL+ G
Sbjct: 69 DERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNG 128
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHI 157
A+ A+D + T A G + +
Sbjct: 129 ADARAQDKFGKTPEDLARDNGYESVARL 156
Score = 83.5 bits (205), Expect = 8e-17, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 38/82 (46%)
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202
+ AA G + ILL A N D G TPLHLA E + ++L+ GA + +
Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNAND 69
Query: 203 KEEKTPLQVAKGGLGLILKRMV 224
+ TPL +A L + ++
Sbjct: 70 ERGHTPLHLAAYTGHLEIVEVL 91
>1WG0-A nrPDB
Length = 243
Score = 179 bits (455), Expect = 7e-46, Method: Composition-based stats.
Identities = 75/215 (34%), Positives = 108/215 (50%), Gaps = 7/215 (3%)
Query: 5 VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV 64
+SN + + +++E + + SL + DQD R LHW+ S EI FLL
Sbjct: 1 MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKME 60
Query: 65 PVND---KDDAGWSPLHIAASAGRDEIVKALLGKG--AQVNAVNQNGCTPLHYAASKNRH 119
VN DD+GW+P HIA S G E+VK+L + +N + G T LH A K
Sbjct: 61 NVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWF 120
Query: 120 EIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAS-TNIQDTEGNTPLHL 178
E++ L+E GA+ KD + +HRAA+ G+LK+I +L S N QD +G TPL
Sbjct: 121 EVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFH 180
Query: 179 ACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQVA 212
A E + A LLV + GA + + + VA
Sbjct: 181 ALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVA 215
Score = 103 bits (258), Expect = 4e-23, Method: Composition-based stats.
Identities = 49/157 (31%), Positives = 74/157 (47%), Gaps = 6/157 (3%)
Query: 76 PLHIAASAGRDEIVKALL-GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
PLH A V+ LL K + + +Q+G PLH++ S HEI LL N +
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64
Query: 135 KDH---YEATAMHRAAAKGNLKMIHILL--YYKASTNIQDTEGNTPLHLACDEERVEEAK 189
D+ T H A + GNL+++ L K N +G T LHLA ++ E ++
Sbjct: 65 DDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQ 124
Query: 190 LLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
L+ GAS+ I++K + PL A L L ++ G
Sbjct: 125 FLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCG 161
>5H76-A nrPDB
Length = 201
Score = 170 bits (430), Expect = 5e-43, Method: Composition-based stats.
Identities = 55/149 (36%), Positives = 84/149 (56%), Gaps = 1/149 (0%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ L+ GA VNA + G TPLH AA EI +LL+ GA+ DA D
Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 69
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+ T +H AA G+L+++ +LL A N D++G TPLHLA +E ++L+ GA
Sbjct: 70 VFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA 129
Query: 197 SIYIENKEEKTPLQVAKGGLGLILKRMVE 225
+ ++K KT ++ L +++
Sbjct: 130 -VNAQDKFGKTAFDISIDNGNEDLAQILA 157
Score = 165 bits (419), Expect = 1e-41, Method: Composition-based stats.
Identities = 58/148 (39%), Positives = 82/148 (55%), Gaps = 1/148 (0%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V L+ G VN D+ G +PLH+AA +G EIV+ LL GA V+A +
Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASD 69
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
G TPLH AA EI +LL+ GA+ +A D T +H AA G L+++ +LL + A
Sbjct: 70 VFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA 129
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLL 191
N QD G T ++ D + A++L
Sbjct: 130 -VNAQDKFGKTAFDISIDNGNEDLAQIL 156
Score = 162 bits (411), Expect = 8e-41, Method: Composition-based stats.
Identities = 59/154 (38%), Positives = 88/154 (57%), Gaps = 2/154 (1%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G+ +E++ ++A+ + D T LH A +GH EIVE LL+ G V+
Sbjct: 10 LLEAARAGQDDEVR-ILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 68
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G++PLH+AA G EIV+ LL GA VNA++ +G TPLH AA EI +LL+ G
Sbjct: 69 DVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHG 128
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
A +A+D + TA + GN + IL +Y+
Sbjct: 129 A-VNAQDKFGKTAFDISIDNGNEDLAQILAFYEI 161
>5HKP-A nrPDB
Length = 351
Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats.
Identities = 72/239 (30%), Positives = 107/239 (44%), Gaps = 24/239 (10%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A SG E+L + +D T LH A IV+ LLQ G V+ K
Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 87
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G PLH A S G E+ + LL GA VNA++ TPLH AASKNR E+ +LL G
Sbjct: 88 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 147
Query: 130 ANPDAKD---------------------HYEATAMHRAAAKGNLKMIHILLYYKASTNIQ 168
A+P + ++ ++ +AA + +L + L + Q
Sbjct: 148 ADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQ 207
Query: 169 DTEGNTPLHLA---CDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
T LH A +R + A+LL+ +GA++ +NK+ TPL VA + ++
Sbjct: 208 PQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL 266
Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats.
Identities = 57/240 (23%), Positives = 88/240 (36%), Gaps = 25/240 (10%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66
+ + N G E+ E +L + D T LH A S E+ LL G
Sbjct: 92 LVPLHNACSYGHY-EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 150
Query: 67 NDKDDAGWSP---------------------LHIAASAGRDEIVKALLGKGAQVNAVNQN 105
+ G S L AA VK L Q+
Sbjct: 151 TLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQS 210
Query: 106 GCTPLHYAASKNRHE---IAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK 162
T LH A + + +A +LL GAN + K+ T +H AA + + ++ +L +
Sbjct: 211 HETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 270
Query: 163 ASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKR 222
A N D+ G T LH A ++ +LL+S G+ I + + T Q+ + IL
Sbjct: 271 AKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSE 330
Score = 76.2 bits (186), Expect = 1e-14, Method: Composition-based stats.
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 125 LLEGGANPDAKDHYEATAMHRAAAKGNLK-MIHILLYYKASTNIQDTEGNTPLHLACDEE 183
L + A Y+ + AA GN + ++ +L + + D +TPLHLA
Sbjct: 10 LADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYN 69
Query: 184 RVEEAKLLVSQGASIYIENKEEKTPLQVA 212
RV +LL+ GA ++ ++K PL A
Sbjct: 70 RVRIVQLLLQHGADVHAKDKGGLVPLHNA 98
>3ZKJ-A nrPDB
Length = 261
Score = 163 bits (413), Expect = 5e-41, Method: Composition-based stats.
Identities = 52/172 (30%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ 98
+ +H A GH + L+ G VN SPLH A G VK LL GAQ
Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQ 61
Query: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
VN V + TPL A + +LL+ GA+ + A+ +H AA +G+++ ++ L
Sbjct: 62 VNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDL-ASPIHEAARRGHVECVNSL 120
Query: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQ 210
+ Y + + + + TPL+LAC+ ++ K L+ GA + + K + +PL
Sbjct: 121 IAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLH 171
Score = 136 bits (343), Expect = 7e-33, Method: Composition-based stats.
Identities = 56/203 (27%), Positives = 84/203 (41%), Gaps = 3/203 (1%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A G L+ ++++ D + LH AC GH V+ LL+ G VN
Sbjct: 6 PMHEAAIHGHQLSLR-NLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 64
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG 128
+PL A +G + V LL GA V + +P+H AA + E L+
Sbjct: 65 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAY 123
Query: 129 GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEA 188
G N D K + T ++ A + LL A N Q ++PLH E A
Sbjct: 124 GGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASEELA 182
Query: 189 KLLVSQGASIYIENKEEKTPLQV 211
LL+ GA +N E K P+++
Sbjct: 183 CLLMDFGADTQAKNAEGKRPVEL 205
Score = 109 bits (273), Expect = 9e-25, Method: Composition-based stats.
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 2/153 (1%)
Query: 74 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
WSP+H AA G ++ L+ +G VN + + +PLH A +LL+ GA +
Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVN 63
Query: 134 AKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVS 193
T + A G+ +++LL + AS +++ +P+H A VE L++
Sbjct: 64 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ-PESDLASPIHEAARRGHVECVNSLIA 122
Query: 194 QGASIYIENKEEKTPLQVA-KGGLGLILKRMVE 225
G +I + TPL +A + +K+++E
Sbjct: 123 YGGNIDHKISHLGTPLYLACENQQRACVKKLLE 155
>4O1O-A nrPDB
Length = 717
Score = 161 bits (408), Expect = 2e-40, Method: Composition-based stats.
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 15/231 (6%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
M+ +E++++ + + ++ + LH A ++V LL+ G
Sbjct: 11 MLTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCL 70
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG 128
+ G +P IA G +++ LL VN + NG T AA R E L E
Sbjct: 71 RKRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYEN 130
Query: 129 GANPDAKDHY----------EATAMHRAAAKGNLKMIHILL-YYKASTNIQDTEGNTPLH 177
GA+ + ATA+ AA KG++ ++ ILL KA + +D G L
Sbjct: 131 GADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALV 190
Query: 178 LACDE----ERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
A + +LL+ GA + + + KTPL +A L L +M+
Sbjct: 191 YALLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQML 241
Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats.
Identities = 55/197 (27%), Positives = 80/197 (40%), Gaps = 16/197 (8%)
Query: 22 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND----------KDD 71
L + +L + D + TA A G E + FL + G VN
Sbjct: 90 LLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRK 149
Query: 72 AGWSPLHIAASAGRDEIVKALL-GKGAQVNAVNQNGCTPLHYAASKNR----HEIAVMLL 126
G + L AA G +V LL A+V+A + G L YA I +LL
Sbjct: 150 GGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLL 209
Query: 127 EGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK-ASTNIQDTEGNTPLHLACDEERV 185
+ GA+ + + T + A + NL ++ +LL + N D EG T L LA +
Sbjct: 210 DHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELRLE 269
Query: 186 EEAKLLVSQGASIYIEN 202
E AKLL +GAS +
Sbjct: 270 EIAKLLCHRGASTNCGD 286
>5ET1-A nrPDB
Length = 353
Score = 159 bits (403), Expect = 8e-40, Method: Composition-based stats.
Identities = 62/209 (29%), Positives = 96/209 (45%), Gaps = 5/209 (2%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV-PVND 68
A G L+ L+ A + D +H A +G + +L++ P
Sbjct: 7 ALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVS 66
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGK-GAQVNAVNQNGCTPLHYAASKNRHEIAVMLL- 126
+ G +P H AA+ G ++ LL + G +V + +G T LH AA ++ LL
Sbjct: 67 RARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLY 126
Query: 127 EGGANPDAKDHYEATAMHRAAAKGNLKMIHILL-YYKASTNIQDTEGNTPLHLACDEERV 185
+GGAN A +H AAAKG+L + +L+ +Y N Q G TPL+LAC E +
Sbjct: 127 QGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHL 186
Query: 186 EEAKLLVSQ-GASIYIENKEEKTPLQVAK 213
E K LV + A ++ ++ TPL A
Sbjct: 187 EVTKYLVQECSADPHLRAQDGMTPLHAAA 215
Score = 133 bits (336), Expect = 5e-32, Method: Composition-based stats.
Identities = 57/208 (27%), Positives = 102/208 (49%), Gaps = 4/208 (1%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQL-GVPVN 67
++ A G + +K + + + T +H+A + G ++ L+ VN
Sbjct: 108 VLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVN 167
Query: 68 DKDDAGWSPLHIAASAGRDEIVKALLGK-GAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 126
+ + G +PL++A G E+ K L+ + A + Q+G TPLH AA + + V L+
Sbjct: 168 AQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLV 227
Query: 127 EGG-ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV 185
+ +DH ATAMH AA++G+ K++ LL + A + QD G TPLH A + +
Sbjct: 228 SFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS-QDLWGGTPLHDAAENGEL 286
Query: 186 EEAKLLVSQGASIYIENKEEKTPLQVAK 213
E ++L GA + + + + T +A+
Sbjct: 287 ECCQILAVNGAGLDVRDHDGYTAADLAE 314
Score = 130 bits (326), Expect = 6e-31, Method: Composition-based stats.
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 3/186 (1%)
Query: 8 LMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL-QLGVPV 66
L + A G L LK + + T L+ AC GH E+ ++L+ +
Sbjct: 141 LPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADP 200
Query: 67 NDKDDAGWSPLHIAASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
+ + G +PLH AA G + ++ L+ + + +G T +H+AAS+ ++ L
Sbjct: 201 HLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWL 260
Query: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV 185
L GA +D + T +H AA G L+ IL A +++D +G T LA
Sbjct: 261 LLHGAEIS-QDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHT 319
Query: 186 EEAKLL 191
++ L
Sbjct: 320 HCSRYL 325
Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats.
Identities = 67/257 (26%), Positives = 107/257 (41%), Gaps = 41/257 (15%)
Query: 8 LMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL-QLGVPV 66
L V + A SGKL L+ + A ++ T H A + G+ +++LL Q G V
Sbjct: 39 LPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRV 98
Query: 67 NDKDDAGWSPLHIAASAGRDEIVKALLGKGAQ---------------------------- 98
+KD++G + LH+AA G ++VK LL +G
Sbjct: 99 QEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLL 158
Query: 99 -------VNAVNQNGCTPLHYAASKNRHEIAVMLL-EGGANPDAKDHYEATAMHRAAAKG 150
VNA NG TPL+ A + E+ L+ E A+P + T +H AA G
Sbjct: 159 VGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMG 218
Query: 151 NLKMIHILLYYKAST--NIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTP 208
+ ++ L+ + A + QD +G T +H A + L+ GA I ++ TP
Sbjct: 219 HNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEI-SQDLWGGTP 276
Query: 209 LQVAKGGLGLILKRMVE 225
L A L +++
Sbjct: 277 LHDAAENGELECCQILA 293
>3EU9-A nrPDB
Length = 240
Score = 157 bits (396), Expect = 5e-39, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 90/188 (47%), Gaps = 2/188 (1%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
++ A + +++ +K I + + T LHWA GH +V L++ G +
Sbjct: 45 LLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSL 104
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNR-HEIAVMLLE 127
D G S +H+AA G IV L+ KG V+ ++QNG TPL +AA + + +LL
Sbjct: 105 IDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLT 164
Query: 128 GGANPDAKDHY-EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVE 186
+ + D Y + TA+H A GN +I +LL A+ + Q+ +G + L LA + V
Sbjct: 165 FNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVW 224
Query: 187 EAKLLVSQ 194
L
Sbjct: 225 MINHLQEA 232
Score = 151 bits (381), Expect = 2e-37, Method: Composition-based stats.
Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Query: 26 ILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-DAGWSPLHIAASAG 84
++ + D+++ T LHWA ++V++ + G V+ D +PLH A G
Sbjct: 28 LVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQG 87
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMH 144
+V L+ GA + ++ GC+ +H AA I L+ G + D D T +
Sbjct: 88 HLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLM 147
Query: 145 RAAAKGN-LKMIHILLYYKASTNIQDTEG-NTPLHLACDEERVEEAKLLVSQGASIYIEN 202
AA + + + +LL + S N+ D NT LH A LL+ GA++ +N
Sbjct: 148 WAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQN 207
Query: 203 KEEKTPLQVAK 213
+ ++ L +AK
Sbjct: 208 IKGESALDLAK 218
Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats.
Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD-AKDHY 138
A G E + L+ G V ++ T LH+AA NR ++ + GA D
Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 75
Query: 139 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
+T +H A +G+L M+ L+ Y A ++ D EG + +HLA L+++G +
Sbjct: 76 NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 135
Query: 199 YIENKEEKTPLQVAK 213
+ ++ TPL A
Sbjct: 136 DMMDQNGMTPLMWAA 150
Score = 77.3 bits (189), Expect = 5e-15, Method: Composition-based stats.
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 6/129 (4%)
Query: 2 EGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGH-TEIVEFLL 60
EGC + ++ + ++A DQ+ T L WA H + LL
Sbjct: 108 EGCSCIHLAAQFGHT----SIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 163
Query: 61 QLGVPVNDKDDAG-WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRH 119
V VN D + LH A AG ++ LL GA V+A N G + L A +
Sbjct: 164 TFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNV 223
Query: 120 EIAVMLLEG 128
+ L E
Sbjct: 224 WMINHLQEA 232
Score = 28.0 bits (61), Expect = 3.7, Method: Composition-based stats.
Identities = 11/44 (25%), Positives = 16/44 (36%)
Query: 179 ACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKR 222
A E + LV G + +KE T L A + L +
Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVK 59
>4OT9-A nrPDB
Length = 359
Score = 152 bits (385), Expect = 8e-38, Method: Composition-based stats.
Identities = 65/218 (29%), Positives = 101/218 (46%), Gaps = 11/218 (5%)
Query: 3 GCVSNLMVCNLAYSGKLEELKESIL--ADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
G + + +E++ I D + T+ +T LH A G T +V FLL
Sbjct: 82 GDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLL 141
Query: 61 QLGVPVNDKDDAGWSPLHIA--ASAGRDEIVKALLGKGAQ-----VNAVNQNGCTPLHYA 113
++G D G S +H+A A AG E+++ALL GA ++ + G P+H A
Sbjct: 142 RVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLA 201
Query: 114 ASKNRHEIAVMLLEGGANPDAKDHYEA-TAMHRAAAKGNLKMIHILL-YYKASTNIQDTE 171
E +L++ GA +A + TA+H A L ++ L+ +A+ N +
Sbjct: 202 VRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFA 261
Query: 172 GNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPL 209
GNTPLHLA +LL+ GA I+ EN+E PL
Sbjct: 262 GNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299
Score = 55.8 bits (133), Expect = 2e-08, Method: Composition-based stats.
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 132 PDAKDHYEATAMHRAAAKGNLKMIH---ILLYYKAS---TNIQDTEGNTPLHLACDEERV 185
A+D T +H A G +I ++++ N+ + TPLHLA +
Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134
Query: 186 EEAKLLVSQGASIYIENKEEKTPLQVA 212
L+ GA + ++ + + +A
Sbjct: 135 SVVSFLLRVGADPALLDRHGDSAMHLA 161
>5CBO-A nrPDB
Length = 176
Score = 143 bits (362), Expect = 4e-35, Method: Composition-based stats.
Identities = 47/120 (39%), Positives = 66/120 (55%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA AG+D+ V+ L+ GA VNA++ G TPLH AA EI +LL+ GA+ +A D
Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
T +H AA G L ++ +LL Y A N QD G T ++ D + A++L A
Sbjct: 67 ATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKA 126
Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats.
Identities = 49/120 (40%), Positives = 64/120 (53%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
L A AG + V L+ G VN D+ G +PLH+AA G EIV+ LL GA VNA +
Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
G TPLH AA I +LL+ GA+ +A+D + TA + GN + IL KA
Sbjct: 67 ATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKA 126
Score = 126 bits (317), Expect = 7e-30, Method: Composition-based stats.
Identities = 33/115 (28%), Positives = 59/115 (51%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
L AA + + +L+ GA+ +A D++ T +H AA G+ +++ +LL Y A N D
Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66
Query: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
G+TPLHLA + ++L+ GA + ++K KT ++ L ++
Sbjct: 67 ATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEIL 121
Score = 123 bits (310), Expect = 5e-29, Method: Composition-based stats.
Identities = 42/121 (34%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A++G+ +E++ ++A+ + D T LH A GH EIVE LL+ G VN
Sbjct: 7 LLEAAHAGQDDEVR-ILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNAS 65
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G +PLH+AA G IV+ LL GA VNA ++ G T + ++A +L +
Sbjct: 66 DATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCKNK 125
Query: 130 A 130
A
Sbjct: 126 A 126
>4Z68-A nrPDB
Length = 155
Score = 143 bits (361), Expect = 6e-35, Method: Composition-based stats.
Identities = 54/150 (36%), Positives = 80/150 (53%), Gaps = 4/150 (2%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGW--SPLHIAASAGRDEIVKALLGKGAQVNA 101
L A AG E V+ L VN +D G +PLH AA R +V+ LL GA V+A
Sbjct: 7 LLEAAKAGDVETVKKLC-TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 161
++ G PLH A S +E+A +L++ GA + D ++ T +H AAAKG ++ +LL +
Sbjct: 66 KDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQH 125
Query: 162 KASTNIQDTEGNTPLHLACDEERVEEAKLL 191
A ++ +GNTPL L + + LL
Sbjct: 126 GADPTKKNRDGNTPLDL-VKDGDTDIQDLL 154
Score = 140 bits (354), Expect = 3e-34, Method: Composition-based stats.
Identities = 48/149 (32%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A +G +E +K+ + T LH+A +VE+LLQ G V+ K
Sbjct: 7 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAK 66
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G PLH A S G E+ + L+ GA VN + TPLH AA+K ++EI +LL+ G
Sbjct: 67 DKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHG 126
Query: 130 ANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
A+P K+ T + G+ + +L
Sbjct: 127 ADPTKKNRDGNTPLDL-VKDGDTDIQDLL 154
Score = 131 bits (329), Expect = 3e-31, Method: Composition-based stats.
Identities = 51/141 (36%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGC--TPLHYAASKNRHEIAVMLLEGGANPDA 134
L AA AG E VK L VN + G TPLH+AA NR + LL+ GA+ A
Sbjct: 7 LLEAAKAGDVETVKKLCTV-QSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
KD +H A + G+ ++ +L+ + A N+ D TPLH A + + E KLL+
Sbjct: 66 KDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQH 125
Query: 195 GASIYIENKEEKTPLQVAKGG 215
GA +N++ TPL + K G
Sbjct: 126 GADPTKKNRDGNTPLDLVKDG 146
>5GP7-A nrPDB
Length = 169
Score = 134 bits (337), Expect = 3e-32, Method: Composition-based stats.
Identities = 50/147 (34%), Positives = 75/147 (51%), Gaps = 3/147 (2%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGW--SPLHIAASAGRDEIVKALLGKG 96
AL A G V+ L +N +D G +PLH+AA E+ + LL G
Sbjct: 8 RGDAALLDAAKKGCLARVQKLC-TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHG 66
Query: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
A VNA ++ G PLH AAS +IA +L++ +A D + T +H AA KG ++
Sbjct: 67 ADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCA 126
Query: 157 ILLYYKASTNIQDTEGNTPLHLACDEE 183
+LL + A +++ EG TPL LA ++
Sbjct: 127 LLLAHGADPTMKNQEGQTPLDLATADD 153
Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats.
Identities = 49/142 (34%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGC--TPLHYAASKNRHEIAVMLLEGGA 130
G + L AA G V+ L +N + G TPLH AA N E+A LLE GA
Sbjct: 9 GDAALLDAAKKGCLARVQKL-CTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGA 67
Query: 131 NPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190
+ +A+D +H AA+ G++ + +L+ Y N D TPLH A + R + L
Sbjct: 68 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 127
Query: 191 LVSQGASIYIENKEEKTPLQVA 212
L++ GA ++N+E +TPL +A
Sbjct: 128 LLAHGADPTMKNQEGQTPLDLA 149
Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats.
Identities = 46/139 (33%), Positives = 68/139 (48%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ + A G L +++ + T + T LH A + E+ E+LL+ G VN +
Sbjct: 13 LLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 72
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G PLH AAS G +I L+ VNA ++ TPLH AA K R ++ +LL G
Sbjct: 73 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHG 132
Query: 130 ANPDAKDHYEATAMHRAAA 148
A+P K+ T + A A
Sbjct: 133 ADPTMKNQEGQTPLDLATA 151
>6EMK-G nrPDB
Length = 426
Score = 131 bits (329), Expect = 3e-31, Method: Composition-based stats.
Identities = 43/140 (30%), Positives = 69/140 (49%), Gaps = 5/140 (3%)
Query: 77 LHIAASAGRDEIVKALLGKGAQV--NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD- 133
L A G IVK LL + + N ++NG + LHYA+ R+ I V L++ G +
Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHE 68
Query: 134 -AKDHYEATAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
K T +H A KG+ + +H+LL + N + G P+H+AC + + LL
Sbjct: 69 LIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLL 128
Query: 192 VSQGASIYIENKEEKTPLQV 211
+ GA +++ + TPL V
Sbjct: 129 IGVGADLWVMDTNGDTPLHV 148
Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats.
Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 8/178 (4%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPV--NDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
L A G+ IV+ LL+ + N + GWS LH A+ GR I L+ G +
Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHE 68
Query: 102 --VNQNGCTPLHYAASKNRHEIAVMLLEGGAN-PDAKDHYEATAMHRAAAKGNLKMIHIL 158
G T +H A K + +LL+ + + +H A + + +L
Sbjct: 69 LIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLL 128
Query: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA---SIYIENKEEKTPLQVAK 213
+ A + DT G+TPLH+ + + K+L+++G + +K P+ VA+
Sbjct: 129 IGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVAQ 186
Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats.
Identities = 41/171 (23%), Positives = 79/171 (46%), Gaps = 7/171 (4%)
Query: 16 SGKLEELKESILADKSLATRTD-QDSRTALHWACSAGHTEIVEFLLQLGVPVND--KDDA 72
G L +K + + L T D ++ ++LH+A G I +L+QLG ++ K
Sbjct: 15 EGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFK 74
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQ-VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131
G + +H+A G ++ + LL + + +N +NG P+H A + ++ +L+ GA+
Sbjct: 75 GNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGAD 134
Query: 132 PDAKDHYEATAMHRAAAKGNLKMIHILLYYKA---STNIQDTEGNTPLHLA 179
D T +H G++ + +LL N++D P+ +A
Sbjct: 135 LWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVA 185
Score = 67.7 bits (164), Expect = 4e-12, Method: Composition-based stats.
Identities = 23/110 (20%), Positives = 41/110 (37%), Gaps = 3/110 (2%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66
N V G + L + ++ R +H AC + + + L+ +G +
Sbjct: 76 NTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADL 135
Query: 67 NDKDDAGWSPLHIAASAGRDEIVKALLGKG---AQVNAVNQNGCTPLHYA 113
D G +PLH+ G +K LL +G N ++ P+ A
Sbjct: 136 WVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVA 185
>3LJN-A nrPDB
Length = 364
Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats.
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 30/187 (16%)
Query: 35 RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLG 94
++D ++ +H A G T+ V L++ GV ++ G + LH+A G + K L
Sbjct: 15 KSDDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLAS 74
Query: 95 KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKM 154
G +V+++ +G P+H A N+ ++ V L+EG AK +M
Sbjct: 75 VG-EVHSL-WHGQKPIHLAVMANKTDLVVALVEG-------------------AKERGQM 113
Query: 155 IHILLY-------YKASTNIQDTEGNTPLH--LACDEERVEEAKLLVSQGASIYIENKEE 205
LL + ++++ +G T LH + E +E K+LV GAS ++K +
Sbjct: 114 PESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKAD 173
Query: 206 KTPLQVA 212
+TPL A
Sbjct: 174 ETPLMRA 180
Score = 69.6 bits (169), Expect = 9e-13, Method: Composition-based stats.
Identities = 41/177 (23%), Positives = 73/177 (41%), Gaps = 22/177 (12%)
Query: 39 DSRTALHWACSAG--HTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALL--- 93
+TALHW G + E+++ L+QLG KD A +PL A E + ++
Sbjct: 137 KGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMDTV 196
Query: 94 --GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGN 151
+++ N+ G + LH+A N ++A+ +E G + + +D+ ++ +
Sbjct: 197 PSKSSLRLDYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAM 256
Query: 152 LKMIHILLYYKASTN-IQDT---EGNTPLHL----------ACDEERVEEAKLLVSQ 194
+ + LL K IQ G T L A D + E +LL +
Sbjct: 257 VLLTKELLQ-KTDVFLIQACPYHNGTTVLPDRVVWLDFVPAAADPSKQEVLQLLQEK 312
Score = 35.0 bits (79), Expect = 0.031, Method: Composition-based stats.
Identities = 15/60 (25%), Positives = 30/60 (50%)
Query: 36 TDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
++ + LHWA ++ +++G+ VN +D+ PL+++ A + K LL K
Sbjct: 207 ANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELLQK 266
>6BOA-A nrPDB
Length = 742
Score = 120 bits (300), Expect = 6e-28, Method: Composition-based stats.
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 19/156 (12%)
Query: 75 SPLHIAASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN-- 131
SPL +AA + + LL + +V+ G T LH AA + E A++L+E
Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 132 --PDAKDHY-EATAMHRAAAKGNLKMIHILLYYKASTNIQDT-------------EGNTP 175
P + Y TA+H A N+ ++ LL +AS + + T G P
Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
Query: 176 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
L A E +LL+ GA I ++ T L +
Sbjct: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats.
Identities = 40/201 (19%), Positives = 74/201 (36%), Gaps = 30/201 (14%)
Query: 42 TALHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQV- 99
+ L A + + LL+ V+ + G + LHIAA E L+ ++
Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 100 ----NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HYEATA 142
+ G T LH A + LL A+ A+ ++
Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV----EEAKLLV---SQG 195
+ AA + +++ +L+ + A QD+ GNT LH+ + + LL+ G
Sbjct: 167 LSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHG 226
Query: 196 ASIY----IENKEEKTPLQVA 212
+ + N + TP ++A
Sbjct: 227 DHLQPLDLVPNHQGLTPFKLA 247
Score = 98.5 bits (244), Expect = 2e-21, Method: Composition-based stats.
Identities = 44/198 (22%), Positives = 66/198 (33%), Gaps = 30/198 (15%)
Query: 3 GCVSNLMVCNLAYSGKLEELKESILADKSLA----TRTDQDSRTALHWACSAGHTEIVEF 58
G + + A LE + A L T + +TALH A + +V
Sbjct: 76 GAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRA 135
Query: 59 LLQLGVPVNDKDDA-------------GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 105
LL V+ + G PL AA +EIV+ L+ GA + A +
Sbjct: 136 LLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSL 195
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPD-----------AKDHYEATAMHRAAAKGNLKM 154
G T LH + A + + D +H T A +GN M
Sbjct: 196 GNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVM 255
Query: 155 IHILLYYKASTNIQDTEG 172
L+ + + Q T G
Sbjct: 256 FQHLMQKR--KHTQWTYG 271
Score = 97.0 bits (240), Expect = 5e-21, Method: Composition-based stats.
Identities = 49/217 (22%), Positives = 83/217 (38%), Gaps = 33/217 (15%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A ++ L + + + + TALH A + E L++ +
Sbjct: 48 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVF 107
Query: 69 KDD-----AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTPL 110
+ G + LHIA +V+ALL + A V+A G PL
Sbjct: 108 EPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPL 167
Query: 111 HYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNL----KMIHILLYYKASTN 166
+AA N EI +L+E GA+ A+D T +H + N +M ++LL Y +
Sbjct: 168 SFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY--DRH 225
Query: 167 ---------IQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ + +G TP LA E + L+ +
Sbjct: 226 GDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
Score = 33.8 bits (76), Expect = 0.062, Method: Composition-based stats.
Identities = 9/42 (21%), Positives = 18/42 (42%), Gaps = 1/42 (2%)
Query: 173 NTPLHLACDEERVEEAKLLVS-QGASIYIENKEEKTPLQVAK 213
+PL LA + V+ L+ + ++ +T L +A
Sbjct: 46 ESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAA 87
>5D68-A nrPDB
Length = 486
Score = 117 bits (294), Expect = 3e-27, Method: Composition-based stats.
Identities = 38/121 (31%), Positives = 64/121 (52%), Gaps = 5/121 (4%)
Query: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG-ANPDA 134
PLH +A G E++ LL + VN ++ + P+HYA + E +LLE G NP+
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLA---CDEERVEEAKL 190
+ ++ +H AA G+ +++ ILL + + +I D +G +PL++ E AKL
Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 160
Query: 191 L 191
L
Sbjct: 161 L 161
Score = 100 bits (248), Expect = 7e-22, Method: Composition-based stats.
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 29 DKSLATRTDQDSRT-----ALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
+S+++ T+ R LH + G +E++ LL VN D W+P+H A
Sbjct: 22 QRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWY 81
Query: 84 GRDEIVKALLGKG-AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG-GANPDAKDHYEAT 141
G+ E + LL KG N +N +PLH+AA EI +LL + D +
Sbjct: 82 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 141
Query: 142 AM 143
+
Sbjct: 142 PL 143
Score = 87.7 bits (216), Expect = 4e-18, Method: Composition-based stats.
Identities = 38/129 (29%), Positives = 55/129 (42%), Gaps = 6/129 (4%)
Query: 5 VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG- 63
V + + A G EL +L+++ + D D +H+AC G E LL+ G
Sbjct: 37 VDDFPLHRSACEGD-SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 95
Query: 64 VPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG-AQVNAVNQNGCTPLHYA---ASKNRH 119
N + SPLH AA G EIV+ LL + +Q G +PL+ N
Sbjct: 96 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWE 155
Query: 120 EIAVMLLEG 128
E A +L E
Sbjct: 156 EAAKLLKEA 164
Score = 71.9 bits (175), Expect = 2e-13, Method: Composition-based stats.
Identities = 23/84 (27%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 142 AMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG-ASIYI 200
+HR+A +G+ +++ LL + S N D++ P+H AC +VE ++L+ +G + +
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 201 ENKEEKTPLQVAKGGLGLILKRMV 224
N + +PL A GG + +++
Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQIL 124
Score = 70.0 bits (170), Expect = 8e-13, Method: Composition-based stats.
Identities = 24/111 (21%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Query: 109 PLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK-ASTNI 167
PLH +A + E+ LL + + D +H A G ++ ILL + N+
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 168 QDTEGNTPLHLACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQVAKGGLG 217
+ + ++PLH A E ++L++ +I +++ ++PL + +
Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 151
>5DND-A nrPDB
Length = 588
Score = 116 bits (290), Expect = 9e-27, Method: Composition-based stats.
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 48 CSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGC 107
AG E ++ L++LG + KD G + LH+AA GRD +V LL +G VNA +++G
Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489
Query: 108 TPLHYAASKNRHEIAVMLLEGGANPDAKDHYE-ATAMHRAAAKGNLKMIHILLYYKASTN 166
+PL A E +L + GA +D + T + R A++ +++ + A
Sbjct: 490 SPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQAGADLQ 549
Query: 167 IQDTEGNTPLHLACDEERVEEAKLL 191
+G + L +A E LL
Sbjct: 550 QPGYDGRSALCVAEAAGNQEVLALL 574
Score = 96.2 bits (238), Expect = 9e-21, Method: Composition-based stats.
Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 2/151 (1%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ LA++G+LE L+ ++ S D + +T LH A G +V LL G+ VN
Sbjct: 425 LALALAHAGELEALQA-LMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNA 483
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN-QNGCTPLHYAASKNRHEIAVMLLE 127
+D G SPL +A E ++ L GA ++ + ++ T L AS+ E +
Sbjct: 484 RDRDGLSPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQ 543
Query: 128 GGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
GA+ + +A+ A A GN +++ +L
Sbjct: 544 AGADLQQPGYDGRSALCVAEAAGNQEVLALL 574
Score = 73.5 bits (179), Expect = 7e-14, Method: Composition-based stats.
Identities = 26/89 (29%), Positives = 41/89 (46%)
Query: 114 ASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
A E L+E G++ KD T +H AA G ++ +LL+ N +D +G
Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489
Query: 174 TPLHLACDEERVEEAKLLVSQGASIYIEN 202
+PL LA E +LL GA + ++
Sbjct: 490 SPLLLAVQGRHRECIRLLRKAGACLSPQD 518
Score = 63.5 bits (153), Expect = 7e-11, Method: Composition-based stats.
Identities = 18/78 (23%), Positives = 37/78 (47%)
Query: 147 AAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEK 206
A G L+ + L+ + ++D+ G T LH+A R +L+ +G + +++
Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489
Query: 207 TPLQVAKGGLGLILKRMV 224
+PL +A G R++
Sbjct: 490 SPLLLAVQGRHRECIRLL 507
>6E2G-A nrPDB
Length = 727
Score = 115 bits (287), Expect = 2e-26, Method: Composition-based stats.
Identities = 45/200 (22%), Positives = 79/200 (39%), Gaps = 29/200 (14%)
Query: 42 TALHWACSAGHTEIVEFLLQ-LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQV- 99
+ L A + + + LL+ G V+ K G + LHIAA E L+ ++
Sbjct: 47 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 100 ----NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HYEATA 142
+ G T LH A + LL GA+ A+ +Y
Sbjct: 107 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 166
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV----EEAKLLVSQGASI 198
+ AA G+ +++ +L+ + A QD+ GNT LH+ + + LL+S
Sbjct: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 226
Query: 199 YIE------NKEEKTPLQVA 212
+++ N + TP ++A
Sbjct: 227 HLKSLELVPNNQGLTPFKLA 246
Score = 107 bits (268), Expect = 4e-24, Method: Composition-based stats.
Identities = 49/214 (22%), Positives = 84/214 (39%), Gaps = 28/214 (13%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A ++ L + + + + TALH A + E L++ +
Sbjct: 48 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVF 107
Query: 69 KDD-----AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTPL 110
+ G + LHIA +V+ALL +GA V+A G PL
Sbjct: 108 EPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPL 167
Query: 111 HYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNL----KMIHILLYYKASTN 166
+AA EI +L+E GA+ A+D T +H + N +M ++LL Y +
Sbjct: 168 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDH 227
Query: 167 ------IQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ + +G TP LA E + + L+ +
Sbjct: 228 LKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 261
Score = 107 bits (267), Expect = 4e-24, Method: Composition-based stats.
Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 29/198 (14%)
Query: 2 EGCVSNLMVCNLAYSGKLEELKESILADKSLA----TRTDQDSRTALHWACSAGHTEIVE 57
+G + + A LE + A L T + +TALH A + +V
Sbjct: 75 KGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVR 134
Query: 58 FLLQLGVPVNDKDDA-------------GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQ 104
LL G V+ + G PL AA G +EIV+ L+ GA + A +
Sbjct: 135 ALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDS 194
Query: 105 NGCTPLHYAASKNRHEIAVMLLEGGANPDAKDH----------YEATAMHRAAAKGNLKM 154
G T LH + A + + D DH T A +GN+ M
Sbjct: 195 LGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVM 254
Query: 155 IHILLYYKASTNIQDTEG 172
L+ + +IQ T G
Sbjct: 255 FQHLMQKR--KHIQWTYG 270
Score = 79.6 bits (195), Expect = 1e-15, Method: Composition-based stats.
Identities = 32/158 (20%), Positives = 48/158 (30%), Gaps = 52/158 (32%)
Query: 106 GCTPLHYAASKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAA----------------- 147
+PL AA +N + + LL+ G K TA+H AA
Sbjct: 45 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 104
Query: 148 ---------------------AKGNLKMIHILLYYKASTNIQDT-------------EGN 173
N+ ++ LL AS + + T G
Sbjct: 105 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 164
Query: 174 TPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
PL A E +LL+ GA I ++ T L +
Sbjct: 165 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats.
Identities = 11/42 (26%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Query: 173 NTPLHLACDEERVEEAKLLVS-QGASIYIENKEEKTPLQVAK 213
+PL LA E V+ L+ +G ++ + +T L +A
Sbjct: 46 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAA 87
>1BLX-B nrPDB
Length = 166
Score = 110 bits (274), Expect = 6e-25, Method: Composition-based stats.
Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 2/146 (1%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
A G ++E++ + + ++ +TAL G + LL+ G N +D +
Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALELLKQGASPNVQDAS 73
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
G SP+H AA G + +K L+ GA VNA++ G P+H A + + L ++
Sbjct: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL-APESDL 132
Query: 133 DAKDHYEATAMHRAAAKGNLKMIHIL 158
+D T + A +G ++ IL
Sbjct: 133 HHRDASGLTPLELARQRGAQNLMDIL 158
Score = 95.8 bits (237), Expect = 1e-20, Method: Composition-based stats.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 47 ACSAGHTEIVEFLL-QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 105
A + G + V LL + V + + G + L + G + LL +GA N + +
Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALELLKQGASPNVQDAS 73
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 165
G +P+H AA + +L+E GA+ +A D + +H A +G+ ++ L ++
Sbjct: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAP-ESDL 132
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ +D G TPL LA +L
Sbjct: 133 HHRDASGLTPLELARQRGAQNLMDILQGH 161
Score = 93.1 bits (230), Expect = 9e-20, Method: Composition-based stats.
Identities = 41/151 (27%), Positives = 74/151 (49%), Gaps = 3/151 (1%)
Query: 77 LHIAASAGRDEIVKALLGKG-AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
L AA+ G + V+ LL + +A+N+ G T L +A+ LL+ GA+P+ +
Sbjct: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSPAVALELLKQGASPNVQ 70
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
D + +H AA G L + +L+ + A N D+ G+ P+HLA E L +
Sbjct: 71 DASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAPE- 129
Query: 196 ASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
+ ++ + TPL++A+ L +++G
Sbjct: 130 SDLHHRDASGLTPLELARQRGAQNLMDILQG 160
>1BD8-A nrPDB
Length = 156
Score = 108 bits (269), Expect = 3e-24, Method: Composition-based stats.
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 2/146 (1%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
A G ++E++ + + ++ +TAL G T I LL+ G N +D +
Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASPNVQDTS 67
Query: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
G SP+H AA G + +K L+ GA VN + G P+H A + V L ++
Sbjct: 68 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGH-TAVVSFLAAESDL 126
Query: 133 DAKDHYEATAMHRAAAKGNLKMIHIL 158
+D T + A +G ++ IL
Sbjct: 127 HRRDARGLTPLELALQRGAQDLVDIL 152
Score = 97.4 bits (241), Expect = 5e-21, Method: Composition-based stats.
Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 47 ACSAGHTEIVEFLL-QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 105
A + G + V LL + V + + G + L + G I LL +GA N + +
Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASPNVQDTS 67
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 165
G +P+H AA + +L+E GA+ + D A +H A +G+ ++ L ++
Sbjct: 68 GTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL-AAESDL 126
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ +D G TPL LA + +L
Sbjct: 127 HRRDARGLTPLELALQRGAQDLVDILQGH 155
Score = 90.8 bits (224), Expect = 4e-19, Method: Composition-based stats.
Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Query: 77 LHIAASAGRDEIVKALLGKG-AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
L AA+ G + V+ LL + +A+N+ G T L IA+ LL+ GA+P+ +
Sbjct: 6 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQ-VMMFGSTAIALELLKQGASPNVQ 64
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
D + +H AA G L + +L+ + A N+ D G P+HLA E L ++
Sbjct: 65 DTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE- 123
Query: 196 ASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
+ ++ + TPL++A L +++G
Sbjct: 124 SDLHRRDARGLTPLELALQRGAQDLVDILQG 154
>2RFA-A nrPDB
Length = 232
Score = 103 bits (257), Expect = 6e-23, Method: Composition-based stats.
Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 29/200 (14%)
Query: 42 TALHWACSAGHTEIVEFLLQ-LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQV- 99
+ L A + + LL+ G V+ + G + LHIAA E L+ ++
Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64
Query: 100 ----NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HYEATA 142
+ G T LH A + LL GA+ A+ +Y
Sbjct: 65 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 124
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV----EEAKLLVSQGASI 198
+ AA G+ +++ +L+ + A QD+ GNT LH+ + + LL+S
Sbjct: 125 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 184
Query: 199 YIE------NKEEKTPLQVA 212
+++ N + TP ++A
Sbjct: 185 HLKSLELVPNNQGLTPFKLA 204
Score = 95.8 bits (237), Expect = 1e-20, Method: Composition-based stats.
Identities = 49/214 (22%), Positives = 84/214 (39%), Gaps = 28/214 (13%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A ++ L + + + + TALH A + E L++ +
Sbjct: 6 PLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVF 65
Query: 69 KDD-----AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTPL 110
+ G + LHIA +V+ALL +GA V+A G PL
Sbjct: 66 EPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPL 125
Query: 111 HYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNL----KMIHILLYYKASTN 166
+AA EI +L+E GA+ A+D T +H + N +M ++LL Y +
Sbjct: 126 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDH 185
Query: 167 ------IQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ + +G TP LA E + + L+ +
Sbjct: 186 LKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 219
Score = 91.2 bits (225), Expect = 3e-19, Method: Composition-based stats.
Identities = 44/185 (23%), Positives = 64/185 (34%), Gaps = 27/185 (14%)
Query: 3 GCVSNLMVCNLAYSGKLEELKESILADKSLA----TRTDQDSRTALHWACSAGHTEIVEF 58
G + + A LE + A L T + +TALH A + +V
Sbjct: 34 GAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRA 93
Query: 59 LLQLGVPVNDKDDA-------------GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 105
LL G V+ + G PL AA G +EIV+ L+ GA + A +
Sbjct: 94 LLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSL 153
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDH----------YEATAMHRAAAKGNLKMI 155
G T LH + A + + D DH T A +GN+ M
Sbjct: 154 GNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMF 213
Query: 156 HILLY 160
L+
Sbjct: 214 QHLMQ 218
Score = 35.0 bits (79), Expect = 0.026, Method: Composition-based stats.
Identities = 11/42 (26%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 173 NTPLHLACDEERVEEAKLLVS-QGASIYIENKEEKTPLQVAK 213
+PL LA E V+ L+ +G ++ +T L +A
Sbjct: 4 ESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAA 45
>6DMR-A nrPDB
Length = 730
Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats.
Identities = 55/216 (25%), Positives = 84/216 (38%), Gaps = 31/216 (14%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A L LK +L + TALH A + E L++ P
Sbjct: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME-AAPELA 106
Query: 69 KDDA------GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTP 109
K+ A G + LHIA +V+ALL +GA V+A G P
Sbjct: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNL----KMIHILLYYKAST 165
L +AA EI +L+E GA+ A+D T +H + N +M ++LL Y +
Sbjct: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
Query: 166 NI-------QDTEGNTPLHLACDEERVEEAKLLVSQ 194
+ + +G TP LA E + L+ +
Sbjct: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
Score = 99.7 bits (247), Expect = 1e-21, Method: Composition-based stats.
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 26/157 (16%)
Query: 40 SRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGRD 86
+TALH A + +V LL G V+ + G PL AA G +
Sbjct: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176
Query: 87 EIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD-----------AK 135
EIV+ L+ GA + A + G T LH + A + + D
Sbjct: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVP 236
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
+H T A +GN M L+ + ++Q T G
Sbjct: 237 NHQGLTPFKLAGVEGNTVMFQHLMQKR--KHVQWTCG 271
Score = 98.9 bits (245), Expect = 1e-21, Method: Composition-based stats.
Identities = 42/214 (19%), Positives = 77/214 (35%), Gaps = 30/214 (14%)
Query: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLL-QLGVPVNDKDDAGWSPLHIAASAGRDE 87
D+ + ++ + L A +++ LL + G + LH+AA E
Sbjct: 34 DRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLE 93
Query: 88 IVKALLGKGAQVNAVNQN-----GCTPLHYAASKNRHEIAVMLLEGGANPDAKD------ 136
L+ ++ G T LH A + LL GA+ A+
Sbjct: 94 AATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR 153
Query: 137 -------HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERV---- 185
+Y + AA G+ +++ +L+ + A QD+ GNT LH+ +
Sbjct: 154 RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFAC 213
Query: 186 EEAKLLVSQGASIY-------IENKEEKTPLQVA 212
+ LL+S + N + TP ++A
Sbjct: 214 QMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLA 247
>4BSZ-B nrPDB
Length = 202
Score = 100 bits (249), Expect = 5e-22, Method: Composition-based stats.
Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 28/152 (18%)
Query: 14 AYSGKLEELKES---ILADKSLAT-RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
A +G L+ LK+ +++ + L+T + + TALH A + GH E V ++L+ N
Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL-EG 128
+D +KA VN VN+ G T LH+A+ + ++ +L E
Sbjct: 82 ED-----------------LKAF------VNEVNKTGNTALHWASLNGKLDVVKLLCDEY 118
Query: 129 GANPDAKDHYEATAMHRAAAKGNLKMIHILLY 160
A+P ++ + A+ A G ++ L
Sbjct: 119 EADPFIRNKFGHDAIFEAENSGKEEVETYFLK 150
Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats.
Identities = 22/98 (22%), Positives = 40/98 (40%), Gaps = 11/98 (11%)
Query: 108 TPLHYAASKNRHEIAVMLLE----------GGANPDAKDHYEATAMHRAAAKGNLKMIHI 157
T LH AA+ E +LE A + + TA+H A+ G L ++ +
Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 113
Query: 158 LL-YYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
L Y+A I++ G+ + A + + E + +
Sbjct: 114 LCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 151
Score = 60.4 bits (145), Expect = 6e-10, Method: Composition-based stats.
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 11/88 (12%)
Query: 139 EATAMHRAAAKGNLKMIHILLY----------YKASTNIQDTEGNTPLHLACDEERVEEA 188
++TA+H AAA G+++ + +L KA N + GNT LH A +++
Sbjct: 52 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 111
Query: 189 KLLVSQG-ASIYIENKEEKTPLQVAKGG 215
KLL + A +I NK + A+
Sbjct: 112 KLLCDEYEADPFIRNKFGHDAIFEAENS 139
Score = 38.0 bits (87), Expect = 0.004, Method: Composition-based stats.
Identities = 12/62 (19%), Positives = 23/62 (37%), Gaps = 10/62 (16%)
Query: 173 NTPLHLACDEERVEEAKLLVS----------QGASIYIENKEEKTPLQVAKGGLGLILKR 222
+T LH+A +E + ++ A + NK T L A L + +
Sbjct: 53 STALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK 112
Query: 223 MV 224
++
Sbjct: 113 LL 114
>5UIL-A nrPDB
Length = 405
Score = 99.3 bits (246), Expect = 1e-21, Method: Composition-based stats.
Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 4/143 (2%)
Query: 23 KESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAAS 82
KE I++ +D+ + AC ++ + L++ + +K+ GWSP+ +AA
Sbjct: 261 KEIIVSTIDYDVVLYKDNFKEILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAY 320
Query: 83 AGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASK----NRHEIAVMLLEGGANPDAKDHY 138
G E++K L+ KGA +N N G T Y + ML++ G + D+
Sbjct: 321 HGNIELIKWLVSKGANINDRNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYK 380
Query: 139 EATAMHRAAAKGNLKMIHILLYY 161
+ T GN ++ ++ +
Sbjct: 381 DYTVFDYLEKSGNKNLLQYMMAF 403
Score = 50.0 bits (118), Expect = 8e-07, Method: Composition-based stats.
Identities = 23/127 (18%), Positives = 52/127 (40%), Gaps = 5/127 (3%)
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
++ + A + + L+ + K+ Y + + AA GN+++I L+ A
Sbjct: 276 KDNFKEILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGA 335
Query: 164 STNIQDTEGNTPLHLACDE----ERVEEAKLLVSQGASIYIENKEEKTPLQ-VAKGGLGL 218
+ N ++ +G T D K+L+ G + + + ++ T + K G
Sbjct: 336 NINDRNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKN 395
Query: 219 ILKRMVE 225
+L+ M+
Sbjct: 396 LLQYMMA 402
>1G3N-B nrPDB
Length = 168
Score = 97.0 bits (240), Expect = 6e-21, Method: Composition-based stats.
Identities = 52/138 (37%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA+ G E + +LL VNA N G T L EIA LL GANPD KD
Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLKD 67
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
+H AA G L + LL ++A NI+D EGN PLHLA E + + LV A
Sbjct: 68 RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127
Query: 197 -SIYIENKEEKTPLQVAK 213
++ N + T +A+
Sbjct: 128 SNVGHRNHKGDTACDLAR 145
Score = 96.6 bits (239), Expect = 8e-21, Method: Composition-based stats.
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 3/156 (1%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ + A G LE+L +L + + RTAL G+ EI LL G + K
Sbjct: 9 LASAAARGDLEQLTS-LLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLK 66
Query: 70 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129
D G++ +H AA AG + ++ LL A VN + G PLH AA + + L++
Sbjct: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
Query: 130 A-NPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAS 164
A N ++H TA A G +++ ++ A
Sbjct: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
Score = 96.2 bits (238), Expect = 9e-21, Method: Composition-based stats.
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 2/151 (1%)
Query: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
A + G E + LLQ V VN ++ G + L + G EI + LL +GA + ++ G
Sbjct: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLKDRTG 70
Query: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA-ST 165
+H AA + LLE A+ + +D+ +H AA +G+L+++ L+ + A +
Sbjct: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
++ +G+T LA R E L+ + GA
Sbjct: 131 GHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
Score = 64.6 bits (156), Expect = 3e-11, Method: Composition-based stats.
Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
L AA++ E LL+ N +A++ + TA+ GN ++ LL A+ +++D
Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLKD 67
Query: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
G +H A ++ + L+ A + IE+ E PL +A L + +
Sbjct: 68 RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122
Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats.
Identities = 13/58 (22%), Positives = 20/58 (34%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV 64
NL + A G L ++ + S + TA A G E+V + G
Sbjct: 104 NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
>3UI2-A nrPDB
Length = 244
Score = 97.0 bits (240), Expect = 6e-21, Method: Composition-based stats.
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
+P AA ++ + LL + V+AV++NG T L + A + +L E GA+ D
Sbjct: 47 TPWWTAARKADEQALSQLL-EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 105
Query: 135 KDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
+D TA+H AA +++ L+ A ++D G T L LA
Sbjct: 106 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151
Score = 81.6 bits (200), Expect = 2e-16, Method: Composition-based stats.
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
T A + + LL+ V+ D+ G + L A G D+ V+ L GA ++
Sbjct: 47 TPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 105
Query: 102 VN-QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRA 146
+ + G T LH AA R E+ L+E GA+ + +D TA+ A
Sbjct: 106 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151
Score = 81.6 bits (200), Expect = 3e-16, Method: Composition-based stats.
Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 108 TPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNI 167
TP AA K + LLE + DA D TA+ A G+ K + +L A +
Sbjct: 47 TPWWTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 105
Query: 168 QDTEGN-TPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLG 217
+D G T LH+A R E + LV GA I +E++ T L++A+ L
Sbjct: 106 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILK 156
Score = 80.0 bits (196), Expect = 7e-16, Method: Composition-based stats.
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-D 71
A + L + + D++ RTAL + G + V L + G ++ +D
Sbjct: 52 AARKADEQALSQLLEDR--DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMR 109
Query: 72 AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
G + LH+AA R E+V+AL+ GA + ++ G T L A
Sbjct: 110 GGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151
>3DEO-A nrPDB
Length = 183
Score = 95.8 bits (237), Expect = 1e-20, Method: Composition-based stats.
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
+P AA ++ + LL + V+AV++NG T L + A + +L E GA+ D
Sbjct: 46 TPWWTAARKADEQALSQLL-EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 104
Query: 135 KDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
+D TA+H AA +++ L+ A ++D G T L LA
Sbjct: 105 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
Score = 80.8 bits (198), Expect = 4e-16, Method: Composition-based stats.
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNA 101
T A + + LL+ V+ D+ G + L A G D+ V+ L GA ++
Sbjct: 46 TPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 104
Query: 102 VN-QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRA 146
+ + G T LH AA R E+ L+E GA+ + +D TA+ A
Sbjct: 105 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
Score = 80.8 bits (198), Expect = 4e-16, Method: Composition-based stats.
Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 108 TPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNI 167
TP AA K + LLE + DA D TA+ A G+ K + +L A +
Sbjct: 46 TPWWTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 104
Query: 168 QDTEGN-TPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLG 217
+D G T LH+A R E + LV GA I +E++ T L++A+ L
Sbjct: 105 RDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILK 155
Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats.
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-D 71
A + L + + D++ RTAL + G + V L + G ++ +D
Sbjct: 51 AARKADEQALSQLLEDR--DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMR 108
Query: 72 AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
G + LH+AA R E+V+AL+ GA + ++ G T L A
Sbjct: 109 GGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
>2KXP-C nrPDB
Length = 118
Score = 95.0 bits (235), Expect = 2e-20, Method: Composition-based stats.
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 15 YSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGW 74
+G L+E+K+ +A RT + R LH+A G EI+EFLL G +N D
Sbjct: 11 KNGDLDEVKDY-VAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHI 69
Query: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPL 110
+PL A G VK LL KGA +G T L
Sbjct: 70 TPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105
Score = 85.0 bits (209), Expect = 2e-17, Method: Composition-based stats.
Identities = 34/100 (34%), Positives = 49/100 (49%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
WA G + V+ + G VN + G PLH AA G+ EI++ LL KGA +NA +
Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPD 65
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAM 143
++ TPL A + +LL GA+ K TA+
Sbjct: 66 KHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105
Score = 82.3 bits (202), Expect = 1e-16, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 4/114 (3%)
Query: 80 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 139
A G + VK + KG VN + G PLHYAA + EI LL GA+ +A D +
Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68
Query: 140 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVS 193
T + A +G++ + +LL A ++ +G T L A D + K L+
Sbjct: 69 ITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALE-ATDN---QAIKALLQ 118
Score = 80.8 bits (198), Expect = 4e-16, Method: Composition-based stats.
Identities = 26/100 (26%), Positives = 40/100 (40%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
+A + + G + + +H AA G L+++ LL A N D
Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPD 65
Query: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPL 209
TPL A E V KLL+S+GA ++ + T L
Sbjct: 66 KHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105
Score = 27.6 bits (60), Expect = 4.4, Method: Composition-based stats.
Identities = 9/46 (19%), Positives = 18/46 (39%)
Query: 179 ACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
A ++E K V++G + + + PL A L + +
Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFL 54
>3T9K-A nrPDB
Length = 390
Score = 94.3 bits (233), Expect = 4e-20, Method: Composition-based stats.
Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
Query: 27 LADKSLATRTD--QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAG 84
LA + + QD+ T L A +A EFLLQ G VN D AG PLH A G
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
+ L +GA + A + G PL A +I +L
Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 90.0 bits (222), Expect = 6e-19, Method: Composition-based stats.
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 93 LGKGAQVNAVN--QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKG 150
L GA VN VN Q+ TPL A + N LL+ GAN + D +H A G
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 151 NLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
+ + + L A +D+EG PL +A + + LL
Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 74.6 bits (182), Expect = 3e-14, Method: Composition-based stats.
Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
Query: 60 LQLGVPVNDKD--DAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKN 117
L G VN + +PL A +A + LL GA VN + G PLH+A
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 118 RHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
+A + L+ GA+ A+D + A N ++ +L
Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 70.0 bits (170), Expect = 8e-13, Method: Composition-based stats.
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
Query: 126 LEGGANPDAKD--HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEE 183
L GA+ + + AT + +A A +L LL A+ N D+ G PLH A
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 184 RVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
A L + +GA + + E + PL +A + ++
Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 57.3 bits (137), Expect = 5e-09, Method: Composition-based stats.
Identities = 21/69 (30%), Positives = 30/69 (43%)
Query: 24 ESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASA 83
E +L + + + D R LH A GHT + L+ G + +D G PL IA
Sbjct: 252 EFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMET 311
Query: 84 GRDEIVKAL 92
+IV L
Sbjct: 312 ANADIVTLL 320
>3EHQ-A nrPDB
Length = 222
Score = 87.7 bits (216), Expect = 3e-18, Method: Composition-based stats.
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL-QLGVPVN 67
+ A G L L+E L ++ D+ TAL+WAC GH +IVE L Q + +N
Sbjct: 76 PLHEAAKRGNLSWLRE-CLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELN 134
Query: 68 DKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103
++ G + LH AA G +IV+ LL KGA+ + N
Sbjct: 135 QQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRN 170
Score = 84.6 bits (208), Expect = 3e-17, Method: Composition-based stats.
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%)
Query: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL-EGGANPDA 134
PLH AA G ++ L VN +++ G T L++A +I ML + +
Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQ 135
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
++ TA+H AA KG ++ +LL A T++++ E +A A LL +
Sbjct: 136 QNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMAT---NAACASLLKKK 192
Score = 84.3 bits (207), Expect = 4e-17, Method: Composition-based stats.
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 43 ALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGK-GAQVNA 101
LH A G+ + L V VN D AG + L+ A G +IV+ L + ++N
Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQ 135
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
N+ G T LH AA K +I +LL GA D ++ + A A ++
Sbjct: 136 QNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLK 190
Score = 83.5 bits (205), Expect = 7e-17, Method: Composition-based stats.
Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 109 PLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK-ASTNI 167
PLH AA + L+ + D +TA++ A G+ ++ +L N
Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQ 135
Query: 168 QDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG 226
Q+ G+T LH A + + +LL+++GA + N E+K +A L + +G
Sbjct: 136 QNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQG 194
Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats.
Identities = 17/88 (19%), Positives = 35/88 (39%), Gaps = 3/88 (3%)
Query: 3 GCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQL 62
G + C+ G + ++ + ++ TALH A G+ +IV+ LL
Sbjct: 106 GSTALYWACH---GGHKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAK 162
Query: 63 GVPVNDKDDAGWSPLHIAASAGRDEIVK 90
G + ++ +A +A ++K
Sbjct: 163 GARTDLRNIEKKLAFDMATNAACASLLK 190
>5UQE-A nrPDB
Length = 520
Score = 87.3 bits (215), Expect = 5e-18, Method: Composition-based stats.
Identities = 33/92 (35%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 2 EGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ 61
V NL+ AY+G + L+ L+ + R D DSRTALH A + GH E+V+FLL+
Sbjct: 415 VKSVINLLFA--AYTGDVSALRRFALSAMDMEQR-DYDSRTALHVAAAEGHVEVVKFLLE 471
Query: 62 L-GVPVNDKDDAGWSPLHIAASAGRDEIVKAL 92
V KD +P+ A G ++ K L
Sbjct: 472 ACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 503
Score = 70.8 bits (172), Expect = 5e-13, Method: Composition-based stats.
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG-GANPDAK 135
L AA G ++ + + + T LH AA++ E+ LLE NP K
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYK 162
D + T M A G+ + IL Y+
Sbjct: 481 DRWNNTPMDEALHFGHHDVFKILQEYQ 507
Score = 61.2 bits (147), Expect = 4e-10, Method: Composition-based stats.
Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN--A 101
L +A G + + + +D + LH+AA+ G E+VK LL + +VN
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFP 479
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEG 128
++ TP+ A H++ +L E
Sbjct: 480 KDRWNNTPMDEALHFGHHDVFKILQEY 506
Score = 60.4 bits (145), Expect = 7e-10, Method: Composition-based stats.
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQ 168
L +AA + + +D+ TA+H AAA+G+++++ LL K + +
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480
Query: 169 DTEGNTPLHLACDEERVEEAKLL 191
D NTP+ A + K+L
Sbjct: 481 DRWNNTPMDEALHFGHHDVFKIL 503
Score = 47.7 bits (112), Expect = 4e-06, Method: Composition-based stats.
Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ-GASIYIE 201
+ AA G++ + +D + T LH+A E VE K L+ + + +
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480
Query: 202 NKEEKTPLQVA 212
++ TP+ A
Sbjct: 481 DRWNNTPMDEA 491
>5U0K-A nrPDB
Length = 141
Score = 86.6 bits (213), Expect = 8e-18, Method: Composition-based stats.
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 3 GCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQL 62
V NL+ AYSG + L+ L+ + + D DSRTALH A + GH E+V+FL++
Sbjct: 24 KTVVNLLFA--AYSGDVSALRRFALSAMDMEQK-DYDSRTALHVAAAEGHIEVVKFLIEA 80
Query: 63 -GVPVNDKDDAGWSPLHIAASAGRDEIVKAL 92
V KD G PL A E+VK L
Sbjct: 81 CKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111
Score = 67.7 bits (164), Expect = 4e-12, Method: Composition-based stats.
Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG-GANPDAK 135
L AA +G ++ + + + T LH AA++ E+ L+E NP AK
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYK 162
D + + A +L+++ +L Y+
Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDYQ 115
Score = 61.9 bits (149), Expect = 2e-10, Method: Composition-based stats.
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN--A 101
L +A +G + + + KD + LH+AA+ G E+VK L + +VN A
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVK-FLIEACKVNPFA 87
Query: 102 VNQNGCTPLHYAASKNRHEIAVML 125
++ G PL A N E+ +L
Sbjct: 88 KDRWGNIPLDDAVQFNHLEVVKLL 111
Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats.
Identities = 16/84 (19%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ-GASIYIE 201
+ AA G++ + +D + T LH+A E +E K L+ + + +
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88
Query: 202 NKEEKTPLQVAKGGLGLILKRMVE 225
++ PL A L + ++++
Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQ 112
>5U0J-A nrPDB
Length = 140
Score = 83.1 bits (204), Expect = 1e-16, Method: Composition-based stats.
Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
M V NL+ AY+G + L+ L+ + R D DSRTALH A + GH E+V+FLL
Sbjct: 21 MVKSVINLLFA--AYTGDVSALRRFALSAMDMEQR-DYDSRTALHVAAAEGHVEVVKFLL 77
Query: 61 QL-GVPVNDKDDAGWSPLHIAASAGRDEIVKAL 92
+ V KD +P+ A G ++ K L
Sbjct: 78 EACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 110
Score = 65.8 bits (159), Expect = 1e-11, Method: Composition-based stats.
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG-GANPDAK 135
L AA G ++ + + + T LH AA++ E+ LLE NP K
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87
Query: 136 DHYEATAMHRAAAKGNLKMIHILLYYK 162
D + T M A G+ + IL Y+
Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEYQ 114
Score = 56.5 bits (135), Expect = 9e-09, Method: Composition-based stats.
Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN--A 101
L +A G + + + +D + LH+AA+ G E+VK LL + +VN
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFP 86
Query: 102 VNQNGCTPLHYAASKNRHEIAVMLLEG 128
++ TP+ A H++ +L E
Sbjct: 87 KDRWNNTPMDEALHFGHHDVFKILQEY 113
Score = 56.1 bits (134), Expect = 1e-08, Method: Composition-based stats.
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQ 168
L +AA + + +D+ TA+H AAA+G+++++ LL K + +
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87
Query: 169 DTEGNTPLHLACDEERVEEAKLL 191
D NTP+ A + K+L
Sbjct: 88 DRWNNTPMDEALHFGHHDVFKIL 110
Score = 44.6 bits (104), Expect = 3e-05, Method: Composition-based stats.
Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ-GASIYIE 201
+ AA G++ + +D + T LH+A E VE K L+ + + +
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87
Query: 202 NKEEKTPLQVA 212
++ TP+ A
Sbjct: 88 DRWNNTPMDEA 98
>4XD0-A nrPDB
Length = 417
Score = 82.7 bits (203), Expect = 1e-16, Method: Composition-based stats.
Identities = 30/138 (21%), Positives = 56/138 (40%), Gaps = 4/138 (2%)
Query: 25 SILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAG 84
IL+ + D+ + AC E + LL+ + +K+ GWSP+ IAA G
Sbjct: 276 LILSTIDYDIKLYSDNFDEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHG 335
Query: 85 RDEIVKALLGKGAQVNAVNQNGCTPLHYAASK----NRHEIAVMLLEGGANPDAKDHYEA 140
++++ L+ KG +N N G T Y + L+ G + KD+
Sbjct: 336 NMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGL 395
Query: 141 TAMHRAAAKGNLKMIHIL 158
+ N+++ + +
Sbjct: 396 SVFDYMRKNKNIELFNFM 413
Score = 53.1 bits (126), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/121 (16%), Positives = 44/121 (36%), Gaps = 4/121 (3%)
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
+ + A E LL+ K+H + + AA GN+ +I L+
Sbjct: 289 SDNFDEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGV 348
Query: 164 STNIQDTEGNTPLHLACDE----ERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLI 219
+ N ++ +G T D + L++ G +++++ E + + +
Sbjct: 349 NINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIE 408
Query: 220 L 220
L
Sbjct: 409 L 409
>1DCQ-A nrPDB
Length = 278
Score = 78.1 bits (191), Expect = 3e-15, Method: Composition-based stats.
Identities = 37/154 (24%), Positives = 61/154 (39%), Gaps = 18/154 (11%)
Query: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML-LEGGANPDAKDHYE 139
A + L V + G A + ++ + L G PD
Sbjct: 120 ARKKHADTAAKLHSLCEAVKTRDIFGL----LQAYADGVDLTEKIPLANGHEPD------ 169
Query: 140 ATAMHRAAA---KGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGA 196
TA+H A + +L ++ L+ + + Q +G+T LH C + E KLL+ A
Sbjct: 170 ETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKA 229
Query: 197 SIYIENKEEKTPLQVAK----GGLGLILKRMVEG 226
SI I N+ +TPL +AK +L + + G
Sbjct: 230 SIEIANESGETPLDIAKRLKHEHCEELLTQALSG 263
Score = 57.7 bits (138), Expect = 4e-09, Method: Composition-based stats.
Identities = 29/130 (22%), Positives = 50/130 (38%), Gaps = 11/130 (8%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTD--------QDSRTALHWACSA---GHTEIVEF 58
+ +L + K ++ + A T+ + TALH A + IV+F
Sbjct: 131 LHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDF 190
Query: 59 LLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNR 118
L+Q ++ + G + LH E +K LL A + N++G TPL A
Sbjct: 191 LVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKH 250
Query: 119 HEIAVMLLEG 128
+L +
Sbjct: 251 EHCEELLTQA 260
>5AN8-A nrPDB
Length = 613
Score = 76.9 bits (188), Expect = 7e-15, Method: Composition-based stats.
Identities = 54/225 (24%), Positives = 82/225 (36%), Gaps = 46/225 (20%)
Query: 16 SGKLEELKESILADKSLATRTDQDSRTALHWAC---SAGHTEIVEFLLQLGVP------- 65
+G LE L+ + +T L A G ++ LL++
Sbjct: 16 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 75
Query: 66 VNDKDDA----GWSPLHIAASAGRDEIVKALLGKGAQVNAVN-------------QNGCT 108
VN + G S LHIA + VK L+ GA V+A G
Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135
Query: 109 PLHYAASKNRHEIAVMLLEG---GANPDAKDHYEATAMHRAAAKGN---------LKMIH 156
PL AA + ++ LLE A+ A+D T +H + ++M
Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195
Query: 157 ILLYYKAS--TNIQ-----DTEGNTPLHLACDEERVEEAKLLVSQ 194
LL A N+Q + EG TPL LA E ++E K ++ +
Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQR 240
Score = 73.1 bits (178), Expect = 8e-14, Method: Composition-based stats.
Identities = 35/157 (22%), Positives = 60/157 (38%), Gaps = 32/157 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-------------DAGWSPLHIAASAG 84
+ALH A + V+ L++ G V+ K G PL +AA
Sbjct: 85 YRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTK 144
Query: 85 RDEIVKALLGKG---AQVNAVNQNGCTPLHYAAS------KNRHEIAVM---LLEGGA-- 130
+ ++V LL A + A + G T LH +N + M LL+ GA
Sbjct: 145 QWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLLQAGARL 204
Query: 131 NPDAK-----DHYEATAMHRAAAKGNLKMIHILLYYK 162
P+ + + T + AA +G +++ +L +
Sbjct: 205 CPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQRE 241
Score = 49.2 bits (116), Expect = 2e-06, Method: Composition-based stats.
Identities = 29/139 (20%), Positives = 49/139 (35%), Gaps = 35/139 (25%)
Query: 110 LHYAASKNRHEIAVMLLEGG--ANPDAKDH------YEATAMHRAAAK---GNLKMIHIL 158
L ++ E LLE + D T + +A G I L
Sbjct: 3 LFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPL 62
Query: 159 LYYKAS-------TNIQDTE----GNTPLHLACDEERVEEAKLLVSQGASIYI------- 200
L N Q T+ G++ LH+A ++ ++ KLLV GA+++
Sbjct: 63 LEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFF 122
Query: 201 -ENK-----EEKTPLQVAK 213
+N+ + PL +A
Sbjct: 123 QKNQDTCFYFGELPLSLAA 141
Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats.
Identities = 8/28 (28%), Positives = 11/28 (39%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPV 66
+ T L A G EI + +LQ
Sbjct: 217 EGLTPLKLAAKEGKIEIFKHILQREFSA 244
>6OO7-A nrPDB
Length = 786
Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats.
Identities = 54/225 (24%), Positives = 82/225 (36%), Gaps = 46/225 (20%)
Query: 16 SGKLEELKESILADKSLATRTDQDSRTALHWAC---SAGHTEIVEFLLQLGVP------- 65
+G LE L+ + +T L A G ++ LL++
Sbjct: 91 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 150
Query: 66 VNDKDDA----GWSPLHIAASAGRDEIVKALLGKGAQVNAVN-------------QNGCT 108
VN + G S LHIA + VK L+ GA V+A G
Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210
Query: 109 PLHYAASKNRHEIAVMLLEG---GANPDAKDHYEATAMHRAAAKGN---------LKMIH 156
PL AA + ++ LLE A+ A+D T +H + ++M
Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270
Query: 157 ILLYYKAS--TNIQ-----DTEGNTPLHLACDEERVEEAKLLVSQ 194
LL A N+Q + EG TPL LA E ++E K ++ +
Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQR 315
Score = 73.1 bits (178), Expect = 8e-14, Method: Composition-based stats.
Identities = 35/157 (22%), Positives = 60/157 (38%), Gaps = 32/157 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-------------DAGWSPLHIAASAG 84
+ALH A + V+ L++ G V+ K G PL +AA
Sbjct: 160 YRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTK 219
Query: 85 RDEIVKALLGKG---AQVNAVNQNGCTPLHYAAS------KNRHEIAVM---LLEGGA-- 130
+ ++V LL A + A + G T LH +N + M LL+ GA
Sbjct: 220 QWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARL 279
Query: 131 NPDAK-----DHYEATAMHRAAAKGNLKMIHILLYYK 162
P+ + + T + AA +G +++ +L +
Sbjct: 280 CPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQRE 316
Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats.
Identities = 32/153 (20%), Positives = 54/153 (35%), Gaps = 35/153 (22%)
Query: 96 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG--ANPDAKDH------YEATAMHRAA 147
GA +N+ L ++ E LLE + D T + +A
Sbjct: 64 GASQPDLNRFDRDRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAV 123
Query: 148 AK---GNLKMIHILLYYKAS-------TNIQDTE----GNTPLHLACDEERVEEAKLLVS 193
G I LL N Q T+ G++ LH+A ++ ++ KLLV
Sbjct: 124 LNLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVE 183
Query: 194 QGASIYI--------ENK-----EEKTPLQVAK 213
GA+++ +N+ + PL +A
Sbjct: 184 NGANVHAKACGHFFQKNQDTCFYFGELPLSLAA 216
Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats.
Identities = 8/28 (28%), Positives = 11/28 (39%)
Query: 39 DSRTALHWACSAGHTEIVEFLLQLGVPV 66
+ T L A G EI + +LQ
Sbjct: 292 EGLTPLKLAAKEGKIEIFKHILQREFSA 319
>1D9S-A nrPDB
Length = 136
Score = 74.6 bits (182), Expect = 3e-14, Method: Composition-based stats.
Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA+ G+ E V+ LL GA NA+N+ G P+ ++A +LL GA P+ D
Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQ-VMMMGSAQVAELLLLHGAEPNCAD 74
Query: 137 HYEAT-AMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 195
T +H AA +G L + +L A ++ D G P+ LA ++ + A+ L +
Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAAT 134
Query: 196 AS 197
Sbjct: 135 GD 136
Score = 69.2 bits (168), Expect = 1e-12, Method: Composition-based stats.
Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 3/126 (2%)
Query: 1 MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLL 60
M G S+ + A G++E +++ + A + ++ R + G ++ E LL
Sbjct: 7 MLGGSSDAGLATAAARGQVETVRQLLEA-GADPNALNRFGRRPIQV-MMMGSAQVAELLL 64
Query: 61 QLGVPVNDKDDAGWS-PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRH 119
G N D A + P+H AA G + + L GA+++ + G P+ A +
Sbjct: 65 LHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHR 124
Query: 120 EIAVML 125
+IA L
Sbjct: 125 DIARYL 130
Score = 64.6 bits (156), Expect = 3e-11, Method: Composition-based stats.
Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
Query: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
AA++ + E LLE GA+P+A + + + G+ ++ +LL + A N D
Sbjct: 19 AAARGQVETVRQLLEAGADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAEPNCADPAT 77
Query: 173 NT-PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMV 224
T P+H A E ++ +L GA + + + + P+ +A+ + R +
Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYL 130
Score = 36.5 bits (83), Expect = 0.010, Method: Composition-based stats.
Identities = 12/61 (19%), Positives = 25/61 (40%)
Query: 164 STNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRM 223
++ + L A +VE + L+ GA N+ + P+QV G + + +
Sbjct: 4 GIHMLGGSSDAGLATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELL 63
Query: 224 V 224
+
Sbjct: 64 L 64
>5IRX-A nrPDB
Length = 636
Score = 71.6 bits (174), Expect = 2e-13, Method: Composition-based stats.
Identities = 37/188 (19%), Positives = 68/188 (36%), Gaps = 38/188 (20%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
++ ++A K + LK+ + A + + +TALH A + +V L++ G V
Sbjct: 70 LLLDVAR--KTDSLKQFVNASYTDSY---YKGQTALHIAIERRNMTLVTLLVENGADVQA 124
Query: 69 KDDA--------------GWSPLHIAASAGRDEIVKALLGK---GAQVNAVNQNGCTPLH 111
+ G PL +AA + IVK LL A ++A + G T LH
Sbjct: 125 AANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 184
Query: 112 YAAS-----KNRHEIAVMLLE----GGANPD-------AKDHYEATAMHRAAAKGNLKMI 155
+ + + GA + T + AA+ G + ++
Sbjct: 185 ALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVL 244
Query: 156 HILLYYKA 163
+L +
Sbjct: 245 AYILQREI 252
Score = 70.8 bits (172), Expect = 5e-13, Method: Composition-based stats.
Identities = 46/204 (22%), Positives = 80/204 (39%), Gaps = 52/204 (25%)
Query: 71 DAGWSPLHIA---ASAGRDEIVKALLGKGAQVNAVNQ-----------NGCTPLHYAASK 116
+ G + L A G+++ + LL + +++ Q G T LH A +
Sbjct: 47 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 106
Query: 117 NRHEIAVMLLEGGANPDA---KDHYEAT-----------AMHRAAAKGNLKMIHILLYY- 161
+ +L+E GA+ A D ++ T + AA L ++ LL
Sbjct: 107 RNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNS 166
Query: 162 --KASTNIQDTEGNTPLH--LACDEERVEEAKL-------LVSQGASIY-------IENK 203
A + +D+ GNT LH + + V+ K ++ GA ++ I N+
Sbjct: 167 WQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNR 226
Query: 204 EEKTPLQVAK-----GGLGLILKR 222
+ TPL +A G L IL+R
Sbjct: 227 KGLTPLALAASSGKIGVLAYILQR 250
Score = 44.2 bits (103), Expect = 5e-05, Method: Composition-based stats.
Identities = 23/116 (19%), Positives = 36/116 (31%), Gaps = 28/116 (24%)
Query: 137 HYEATAMHRA---AAKGNLKMIHILL-------YYKASTNIQDT----EGNTPLHLACDE 182
T + +A G I +LL K N T +G T LH+A +
Sbjct: 47 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 106
Query: 183 ERVEEAKLLVSQGASIYIENK--------------EEKTPLQVAKGGLGLILKRMV 224
+ LLV GA + + PL +A L + + +
Sbjct: 107 RNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFL 162
>6DVZ-A nrPDB
Length = 791
Score = 71.2 bits (173), Expect = 3e-13, Method: Composition-based stats.
Identities = 51/235 (21%), Positives = 82/235 (34%), Gaps = 56/235 (23%)
Query: 16 SGKLEELKESILADKSLATR---------------TDQDSRTALHWACSA---GHTEIVE 57
G +EEL+E + + L R +T L A EIV
Sbjct: 129 EGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVR 188
Query: 58 FLLQLGVPVNDKDD-----------AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN- 105
LL + D G + L+IA + +I L+ GA VNA +
Sbjct: 189 ILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGV 248
Query: 106 -------------GCTPLHYAASKNRHEIAVMLLEGG-ANPDAKDHYEATAMHRAAAKGN 151
G TPL AA N+ EI +L+E + ++D +H
Sbjct: 249 FFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAE 308
Query: 152 ---------LKMIHILLYYKAS---TNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+M ++L + +++ +G TPL LA + E K ++S+
Sbjct: 309 DFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 363
Score = 65.4 bits (158), Expect = 2e-11, Method: Composition-based stats.
Identities = 36/176 (20%), Positives = 53/176 (30%), Gaps = 45/176 (25%)
Query: 80 AASAGRDEIVKALLG---------KGAQVNA-------VNQNGCTPLHYAASK---NRHE 120
A S G E ++ LL +G V + G T L A N E
Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 185
Query: 121 IAVMLLEGGANPDAKDHY-----------EATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
I +LL D D + TA++ A + + +L+ A N
Sbjct: 186 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHA 245
Query: 170 T--------------EGNTPLHLACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQ 210
G TPL LA + E +LL+ I ++ L
Sbjct: 246 KGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 301
Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats.
Identities = 35/178 (19%), Positives = 67/178 (37%), Gaps = 30/178 (16%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
LA++ + + L I A+ T + +TAL+ A +I L+ G VN
Sbjct: 191 LAFAEENDILDRFINAEY---TEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKG 247
Query: 73 --------------GWSPLHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAA--- 114
G +PL +AA + EIV+ L+ + + + G LH
Sbjct: 248 VFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVA 307
Query: 115 --SKNRHEIAV------MLLEGGANPDA-KDHYEATAMHRAAAKGNLKMIHILLYYKA 163
K +++ +L G + +++ T + AA G +++ +L +
Sbjct: 308 EDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSREI 365
Score = 37.3 bits (85), Expect = 0.005, Method: Composition-based stats.
Identities = 20/99 (20%), Positives = 42/99 (42%), Gaps = 12/99 (12%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALH--WACSAG---HTEIVE-----F 58
+ A + + E ++ + +++ T D LH + + V+
Sbjct: 265 PLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMI 324
Query: 59 LLQLGV--PVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
LL+ G +++ G +PL +AA G+ EI+K +L +
Sbjct: 325 LLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 363
>2A5E-A nrPDB
Length = 156
Score = 70.8 bits (172), Expect = 5e-13, Method: Composition-based stats.
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L AA+ GR E V+ALL GA NA N G P+ +A +LL GA P+ D
Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74
Query: 137 HYEAT-AMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
T +H AA +G L + +L A +++D G P+ LA + + A+ L
Sbjct: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130
Score = 66.9 bits (162), Expect = 7e-12, Method: Composition-based stats.
Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 3/117 (2%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
+ A G++EE++ + A +L + R + G + E LL G N
Sbjct: 16 LATAAARGRVEEVRALLEA-GALPNAPNSYGRRPIQV-MMMGSARVAELLLLHGAEPNCA 73
Query: 70 DDAGWS-PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
D A + P+H AA G + + L GA+++ + G P+ A ++A L
Sbjct: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130
Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats.
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Query: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
AA++ R E LLE GA P+A + Y + G+ ++ +LL + A N D
Sbjct: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRPIQV-MMMGSARVAELLLLHGAEPNCADPAT 77
Query: 173 NT-PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKG 214
T P+H A E ++ +L GA + + + + P+ +A+
Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120
Score = 32.6 bits (73), Expect = 0.14, Method: Composition-based stats.
Identities = 13/36 (36%), Positives = 17/36 (47%)
Query: 176 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
L A RVEE + L+ GA N + P+QV
Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQV 51
>6BO5-A nrPDB
Length = 695
Score = 70.4 bits (171), Expect = 6e-13, Method: Composition-based stats.
Identities = 47/203 (23%), Positives = 70/203 (34%), Gaps = 46/203 (22%)
Query: 38 QDSRTALHWAC---SAGHTEIVEFLLQLGVP-------VNDKDDA----GWSPLHIAASA 83
+T L A G + LLQ+ VN + G S LHIA
Sbjct: 75 STGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEK 134
Query: 84 GRDEIVKALLGKGAQVNAVN-------------QNGCTPLHYAASKNRHEIAVMLLEGG- 129
+ VK L+ GA V+ G PL AA + ++ LLE
Sbjct: 135 RSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPH 194
Query: 130 --ANPDAKDHYEATAMHRAAAKGN---------LKMIHILLYYKAST-------NIQDTE 171
A+ +A D T +H + + M LL A I + +
Sbjct: 195 QPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQ 254
Query: 172 GNTPLHLACDEERVEEAKLLVSQ 194
G TPL LA E ++E + ++ +
Sbjct: 255 GLTPLKLAAKEGKIEIFRHILQR 277
Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats.
Identities = 34/157 (21%), Positives = 59/157 (37%), Gaps = 32/157 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-------------DAGWSPLHIAASAG 84
+ALH A + V+ L++ G V+ + G PL +AA
Sbjct: 122 YQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTK 181
Query: 85 RDEIVKALLGKG---AQVNAVNQNGCTPLH----YAASKNRHEIAVM-----LLEGGANP 132
+ ++V LL A + A + G T LH A + + V+ LL+ GA
Sbjct: 182 QWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARL 241
Query: 133 DAK-------DHYEATAMHRAAAKGNLKMIHILLYYK 162
+H T + AA +G +++ +L +
Sbjct: 242 CPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 278
Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats.
Identities = 51/245 (20%), Positives = 84/245 (34%), Gaps = 55/245 (22%)
Query: 36 TDQDSRTALHWACSAGHTEIVEFLLQLGV--------PVNDKDDAGWSPLHIAA---SAG 84
D+ R L S G E + LL+ + G + L A G
Sbjct: 32 PDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDG 91
Query: 85 RDEIVKALLGKGAQ-------VNAVNQN----GCTPLHYAASKNRHEIAVMLLEGGANPD 133
+ + LL VNA + G + LH A K + +L+E GA+
Sbjct: 92 VNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVH 151
Query: 134 AKD-------------HYEATAMHRAAAKGNLKMIHILLYY---KASTNIQDTEGNTPLH 177
+ ++ + AA ++ LL AS D+ GNT LH
Sbjct: 152 LRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 211
Query: 178 --LACDEERVEEAKL-------LVSQGAS--IYIE-----NKEEKTPLQV-AKGGLGLIL 220
+ + E + L L+ GA ++ N + TPL++ AK G I
Sbjct: 212 ALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIF 271
Query: 221 KRMVE 225
+ +++
Sbjct: 272 RHILQ 276
>5HI9-A nrPDB
Length = 770
Score = 70.4 bits (171), Expect = 6e-13, Method: Composition-based stats.
Identities = 47/203 (23%), Positives = 70/203 (34%), Gaps = 46/203 (22%)
Query: 38 QDSRTALHWAC---SAGHTEIVEFLLQLGVP-------VNDKDDA----GWSPLHIAASA 83
+T L A G + LLQ+ VN + G S LHIA
Sbjct: 115 STGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEK 174
Query: 84 GRDEIVKALLGKGAQVNAVN-------------QNGCTPLHYAASKNRHEIAVMLLEGG- 129
+ VK L+ GA V+ G PL AA + ++ LLE
Sbjct: 175 RSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPH 234
Query: 130 --ANPDAKDHYEATAMHRAAAKGN---------LKMIHILLYYKAST-------NIQDTE 171
A+ +A D T +H + + M LL A I + +
Sbjct: 235 QPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQ 294
Query: 172 GNTPLHLACDEERVEEAKLLVSQ 194
G TPL LA E ++E + ++ +
Sbjct: 295 GLTPLKLAAKEGKIEIFRHILQR 317
Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats.
Identities = 34/157 (21%), Positives = 59/157 (37%), Gaps = 32/157 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-------------DAGWSPLHIAASAG 84
+ALH A + V+ L++ G V+ + G PL +AA
Sbjct: 162 YQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTK 221
Query: 85 RDEIVKALLGKG---AQVNAVNQNGCTPLH----YAASKNRHEIAVM-----LLEGGANP 132
+ ++V LL A + A + G T LH A + + V+ LL+ GA
Sbjct: 222 QWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARL 281
Query: 133 DAK-------DHYEATAMHRAAAKGNLKMIHILLYYK 162
+H T + AA +G +++ +L +
Sbjct: 282 CPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 318
Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats.
Identities = 51/247 (20%), Positives = 84/247 (34%), Gaps = 55/247 (22%)
Query: 34 TRTDQDSRTALHWACSAGHTEIVEFLLQLGV--------PVNDKDDAGWSPLHIAA---S 82
D+ R L S G E + LL+ + G + L A
Sbjct: 70 QEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQ 129
Query: 83 AGRDEIVKALLGKGAQ-------VNAVNQN----GCTPLHYAASKNRHEIAVMLLEGGAN 131
G + + LL VNA + G + LH A K + +L+E GA+
Sbjct: 130 DGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGAD 189
Query: 132 PDAKD-------------HYEATAMHRAAAKGNLKMIHILLYY---KASTNIQDTEGNTP 175
+ ++ + AA ++ LL AS D+ GNT
Sbjct: 190 VHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTV 249
Query: 176 LH--LACDEERVEEAKL-------LVSQGAS--IYIE-----NKEEKTPLQV-AKGGLGL 218
LH + + E + L L+ GA ++ N + TPL++ AK G
Sbjct: 250 LHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIE 309
Query: 219 ILKRMVE 225
I + +++
Sbjct: 310 IFRHILQ 316
>2F37-A nrPDB
Length = 251
Score = 68.1 bits (165), Expect = 3e-12, Method: Composition-based stats.
Identities = 32/157 (20%), Positives = 59/157 (37%), Gaps = 32/157 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKD-------------DAGWSPLHIAASAG 84
+ALH A + V+ L++ G V+ + G PL +AA
Sbjct: 93 YRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTK 152
Query: 85 RDEIVKALLGKG---AQVNAVNQNGCTPLHYAASKNRHEIAVM---------LLEGGANP 132
+ ++V LL A + A + G T LH + + + LL+ GA
Sbjct: 153 QWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARL 212
Query: 133 -------DAKDHYEATAMHRAAAKGNLKMIHILLYYK 162
D ++ + T + AA +G +++ +L +
Sbjct: 213 CPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQRE 249
Score = 64.2 bits (155), Expect = 5e-11, Method: Composition-based stats.
Identities = 49/203 (24%), Positives = 74/203 (36%), Gaps = 46/203 (22%)
Query: 38 QDSRTALHWACSA---GHTEIVEFLLQLGVP-------VNDK--DDA--GWSPLHIAASA 83
+T L A G + LLQ+ VN + DD G S LHIA
Sbjct: 46 STGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEK 105
Query: 84 GRDEIVKALLGKGAQVNAVN-------------QNGCTPLHYAASKNRHEIAVMLLEG-- 128
+ VK L+ GA V+A G PL AA + ++ LLE
Sbjct: 106 RSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPH 165
Query: 129 -GANPDAKDHYEATAMHRAAA-----KGNLKMIHI----LLYYKAST-------NIQDTE 171
A+ A D T +H N+ ++ LL A +I++ +
Sbjct: 166 QPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQ 225
Query: 172 GNTPLHLACDEERVEEAKLLVSQ 194
TPL LA E ++E + ++ +
Sbjct: 226 DLTPLKLAAKEGKIEIFRHILQR 248
Score = 56.5 bits (135), Expect = 9e-09, Method: Composition-based stats.
Identities = 26/138 (18%), Positives = 50/138 (36%), Gaps = 30/138 (21%)
Query: 103 NQNGCTPLHYAASK---NRHEIAVMLLEGGAN-------PDAK---DHY-EATAMHRAAA 148
G T L A + + LL+ + +A+ D+Y +A+H A
Sbjct: 45 GSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIE 104
Query: 149 KGNLKMIHILLYYKASTNIQDT-------------EGNTPLHLACDEERVEEAKLLVSQ- 194
K +L+ + +L+ A+ + + G PL LA ++ + L+
Sbjct: 105 KRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENP 164
Query: 195 --GASIYIENKEEKTPLQ 210
AS+ + + T L
Sbjct: 165 HQPASLQATDSQGNTVLH 182
Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats.
Identities = 22/103 (21%), Positives = 37/103 (35%), Gaps = 27/103 (26%)
Query: 138 YEATAMHRAAAK---GNLKMIHILLYYKAS-------TNIQDTE----GNTPLHLACDEE 183
T + +A G I LL N Q T+ G++ LH+A ++
Sbjct: 47 TGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKR 106
Query: 184 RVEEAKLLVSQGASIYIEN-------------KEEKTPLQVAK 213
++ KLLV GA+++ + PL +A
Sbjct: 107 SLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAA 149
>2NYJ-A nrPDB
Length = 273
Score = 67.3 bits (163), Expect = 5e-12, Method: Composition-based stats.
Identities = 37/188 (19%), Positives = 68/188 (36%), Gaps = 38/188 (20%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
++ ++A K + LK+ + A + + +TALH A + +V L++ G V
Sbjct: 75 LLLDVAR--KTDSLKQFVNASYTDSY---YKGQTALHIAIERRNMTLVTLLVENGADVQA 129
Query: 69 KDDA--------------GWSPLHIAASAGRDEIVKALLGK---GAQVNAVNQNGCTPLH 111
+ G PL +AA + IVK LL A ++A + G T LH
Sbjct: 130 AANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 189
Query: 112 YAAS-----KNRHEIAVMLLE----GGANPD-------AKDHYEATAMHRAAAKGNLKMI 155
+ + + GA + T + AA+ G + ++
Sbjct: 190 ALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVL 249
Query: 156 HILLYYKA 163
+L +
Sbjct: 250 AYILQREI 257
Score = 65.8 bits (159), Expect = 2e-11, Method: Composition-based stats.
Identities = 46/204 (22%), Positives = 80/204 (39%), Gaps = 52/204 (25%)
Query: 71 DAGWSPLHIA---ASAGRDEIVKALLGKGAQVNAVNQ-----------NGCTPLHYAASK 116
+ G + L A G+++ + LL + +++ Q G T LH A +
Sbjct: 52 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 111
Query: 117 NRHEIAVMLLEGGANPDA---KDHYEAT-----------AMHRAAAKGNLKMIHILLYY- 161
+ +L+E GA+ A D ++ T + AA L ++ LL
Sbjct: 112 RNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNS 171
Query: 162 --KASTNIQDTEGNTPLH--LACDEERVEEAKL-------LVSQGASIY-------IENK 203
A + +D+ GNT LH + + V+ K ++ GA ++ I N+
Sbjct: 172 WQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNR 231
Query: 204 EEKTPLQVAK-----GGLGLILKR 222
+ TPL +A G L IL+R
Sbjct: 232 KGLTPLALAASSGKIGVLAYILQR 255
Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats.
Identities = 23/116 (19%), Positives = 36/116 (31%), Gaps = 28/116 (24%)
Query: 137 HYEATAMHRA---AAKGNLKMIHILL-------YYKASTNIQDT----EGNTPLHLACDE 182
T + +A G I +LL K N T +G T LH+A +
Sbjct: 52 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 111
Query: 183 ERVEEAKLLVSQGASIYIENK--------------EEKTPLQVAKGGLGLILKRMV 224
+ LLV GA + + PL +A L + + +
Sbjct: 112 RNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFL 167
>4N5Q-A nrPDB
Length = 257
Score = 66.5 bits (161), Expect = 1e-11, Method: Composition-based stats.
Identities = 51/235 (21%), Positives = 82/235 (34%), Gaps = 56/235 (23%)
Query: 16 SGKLEELKESILADKSLATR---------------TDQDSRTALHWACSA---GHTEIVE 57
G +EEL+E + + L R +T L A EIV
Sbjct: 13 EGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVR 72
Query: 58 FLLQLGVPVNDKDD-----------AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN- 105
LL + D G + L+IA + +I L+ GA VNA +
Sbjct: 73 ILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGV 132
Query: 106 -------------GCTPLHYAASKNRHEIAVMLLEGG-ANPDAKDHYEATAMHRAAAKGN 151
G TPL AA N+ EI +L+E + ++D +H
Sbjct: 133 FFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAE 192
Query: 152 ---------LKMIHILLYYKAS---TNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
+M ++L + +++ +G TPL LA + E K ++S+
Sbjct: 193 DFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247
Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats.
Identities = 36/176 (20%), Positives = 53/176 (30%), Gaps = 45/176 (25%)
Query: 80 AASAGRDEIVKALLG---------KGAQVNA-------VNQNGCTPLHYAASK---NRHE 120
A S G E ++ LL +G V + G T L A N E
Sbjct: 10 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 69
Query: 121 IAVMLLEGGANPDAKDHY-----------EATAMHRAAAKGNLKMIHILLYYKASTNIQD 169
I +LL D D + TA++ A + + +L+ A N
Sbjct: 70 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHA 129
Query: 170 T--------------EGNTPLHLACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQ 210
G TPL LA + E +LL+ I ++ L
Sbjct: 130 KGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 185
Score = 58.8 bits (141), Expect = 2e-09, Method: Composition-based stats.
Identities = 35/178 (19%), Positives = 67/178 (37%), Gaps = 30/178 (16%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
LA++ + + L I A+ T + +TAL+ A +I L+ G VN
Sbjct: 75 LAFAEENDILDRFINAEY---TEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKG 131
Query: 73 --------------GWSPLHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAA--- 114
G +PL +AA + EIV+ L+ + + + G LH
Sbjct: 132 VFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVA 191
Query: 115 --SKNRHEIAV------MLLEGGANPDA-KDHYEATAMHRAAAKGNLKMIHILLYYKA 163
K +++ +L G + +++ T + AA G +++ +L +
Sbjct: 192 EDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSREI 249
Score = 35.3 bits (80), Expect = 0.024, Method: Composition-based stats.
Identities = 20/99 (20%), Positives = 42/99 (42%), Gaps = 12/99 (12%)
Query: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALH--WACSAG---HTEIVE-----F 58
+ A + + E ++ + +++ T D LH + + V+
Sbjct: 149 PLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMI 208
Query: 59 LLQLGV--PVNDKDDAGWSPLHIAASAGRDEIVKALLGK 95
LL+ G +++ G +PL +AA G+ EI+K +L +
Sbjct: 209 LLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247
>2ETB-A nrPDB
Length = 256
Score = 65.4 bits (158), Expect = 2e-11, Method: Composition-based stats.
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 32/155 (20%)
Query: 72 AGWSPLHIAASAGRDEIVKALLGKGAQVNAVN-------------QNGCTPLHYAASKNR 118
G S LHIA + VK L+ GA V+ G PL AA +
Sbjct: 89 QGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQ 148
Query: 119 HEIAVMLLEG---GANPDAKDHYEATAMHRAAAKGN---------LKMIHILLYYKAST- 165
++ LLE A+ +A D T +H + + M LL A
Sbjct: 149 WDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLC 208
Query: 166 ------NIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
I + +G TPL LA E ++E + ++ +
Sbjct: 209 PTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 243
Score = 63.1 bits (152), Expect = 9e-11, Method: Composition-based stats.
Identities = 36/163 (22%), Positives = 61/163 (37%), Gaps = 33/163 (20%)
Query: 96 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HYEATA 142
AQ G + LH A K + +L+E GA+ + ++
Sbjct: 80 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 139
Query: 143 MHRAAAKGNLKMIHILLYY---KASTNIQDTEGNTPLH--LACDEERVEEAKL------- 190
+ AA ++ LL AS D+ GNT LH + + E + L
Sbjct: 140 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 199
Query: 191 LVSQGAS--IYIE-----NKEEKTPLQV-AKGGLGLILKRMVE 225
L+ GA ++ N + TPL++ AK G I + +++
Sbjct: 200 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 242
Score = 43.8 bits (102), Expect = 6e-05, Method: Composition-based stats.
Identities = 22/103 (21%), Positives = 37/103 (35%), Gaps = 27/103 (26%)
Query: 138 YEATAMHRAAAK---GNLKMIHILLYYKAS-------TNIQDTE----GNTPLHLACDEE 183
T + +A G I LL N Q T+ G++ LH+A ++
Sbjct: 42 TGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKR 101
Query: 184 RVEEAKLLVSQGASIYIEN-------------KEEKTPLQVAK 213
++ KLLV GA +++ + PL +A
Sbjct: 102 SLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAA 144
>6CV9-A nrPDB
Length = 842
Score = 64.6 bits (156), Expect = 3e-11, Method: Composition-based stats.
Identities = 33/149 (22%), Positives = 53/149 (35%), Gaps = 32/149 (21%)
Query: 77 LHIAASAGRDEIVKALLG--KGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
AA G +V+ +L VN V+ G L A + EI +LL+
Sbjct: 13 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV 72
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKA-------------------STNIQDTEGN-- 173
D A+ A +KG ++++ +L + A D +G
Sbjct: 73 GD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRF 127
Query: 174 ----TPLHLACDEERVEEAKLLVSQGASI 198
TP+ LA + E L+ +GA I
Sbjct: 128 SHDVTPIILAAHCQEYEIVHTLLRKGARI 156
Score = 53.1 bits (126), Expect = 1e-07, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 46/146 (31%), Gaps = 32/146 (21%)
Query: 47 ACSAGHTEIVEFLLQ--LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQ 104
A G+ +V +L+ + VN D G + L +A + EI + LL K +
Sbjct: 16 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 74
Query: 105 NGCTPLHYAASKNRHEIAVMLLEGGA--------------NPDAKDHYEA---------- 140
L A SK I +L A D Y
Sbjct: 75 ----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 130
Query: 141 -TAMHRAAAKGNLKMIHILLYYKAST 165
T + AA +++H LL A
Sbjct: 131 VTPIILAAHCQEYEIVHTLLRKGARI 156
Score = 51.5 bits (122), Expect = 3e-07, Method: Composition-based stats.
Identities = 36/147 (24%), Positives = 53/147 (36%), Gaps = 31/147 (21%)
Query: 10 VCNLAYSGKLEELKESILADKSL-ATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A G + +++ + SL D + AL A + H EI E LL+
Sbjct: 13 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV 72
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGA-------------------QVNAVNQNGC-- 107
D L +A S G IV+A+L A A +++G
Sbjct: 73 GD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRF 127
Query: 108 ----TPLHYAASKNRHEIAVMLLEGGA 130
TP+ AA +EI LL GA
Sbjct: 128 SHDVTPIILAAHCQEYEIVHTLLRKGA 154
Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats.
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 30/115 (26%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
LA + + E+ E +L ++L+ D AL A S G+ IVE +L K
Sbjct: 47 ALQLAVANEHLEITELLLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGK 101
Query: 70 -------------------DDAGW------SPLHIAASAGRDEIVKALLGKGAQV 99
D+ G +P+ +AA EIV LL KGA++
Sbjct: 102 RLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARI 156
>3LVQ-E nrPDB
Length = 497
Score = 63.8 bits (154), Expect = 5e-11, Method: Composition-based stats.
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 77 LHIAASAGR---DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
LH+A +V ++ G ++A +G T LHYAA N+ + +LL+G A
Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234
Query: 134 AKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHL 178
+ TA+ A K + + +L +A T PLH+
Sbjct: 235 TVNEAGETALDIARKKHHKECEELLEQAQAGTFA------FPLHV 273
Score = 63.1 bits (152), Expect = 9e-11, Method: Composition-based stats.
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 9/106 (8%)
Query: 109 PLHYA---ASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 165
LH A A++ + +++ G + DAK TA+H AA + +LL +A
Sbjct: 174 VLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALV 233
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
+ G T L +A + E +LL + PL V
Sbjct: 234 GTVNEAGETALDIARKKHHKECEELLEQ------AQAGTFAFPLHV 273
Score = 63.1 bits (152), Expect = 9e-11, Method: Composition-based stats.
Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Query: 143 MHRAAAKGN---LKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
+H A N L ++ ++ + + +GNT LH A + + KLL+ A +
Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234
Query: 200 IENKEEKTPLQVAKGGLGLILKRMVE 225
N+ +T L +A+ + ++E
Sbjct: 235 TVNEAGETALDIARKKHHKECEELLE 260
Score = 59.6 bits (143), Expect = 1e-09, Method: Composition-based stats.
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 44 LHWA---CSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN 100
LH A + +V+F++Q G ++ K G + LH AA + + +K LL A V
Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234
Query: 101 AVNQNGCTPLHYAASKNRHEIAVMLLEGGA 130
VN+ G T L A K+ E +L + A
Sbjct: 235 TVNEAGETALDIARKKHHKECEELLEQAQA 264
Score = 51.5 bits (122), Expect = 3e-07, Method: Composition-based stats.
Identities = 20/88 (22%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Query: 5 VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV 64
+ + +A L L + I+ + D TALH+A + ++ LL+
Sbjct: 173 LVLHLAVKVANQASL-PLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRA 231
Query: 65 PVNDKDDAGWSPLHIAASAGRDEIVKAL 92
V ++AG + L IA E + L
Sbjct: 232 LVGTVNEAGETALDIARKKHHKECEELL 259
Score = 30.3 bits (67), Expect = 0.65, Method: Composition-based stats.
Identities = 18/73 (24%), Positives = 27/73 (36%), Gaps = 7/73 (9%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66
N + A + + LK +L ++L ++ TAL A H E E L Q
Sbjct: 208 NTALHYAALYNQPDCLK-LLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT 266
Query: 67 NDKDDAGWSPLHI 79
PLH+
Sbjct: 267 FAF------PLHV 273
>6CUD-A nrPDB
Length = 806
Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats.
Identities = 32/149 (21%), Positives = 54/149 (36%), Gaps = 32/149 (21%)
Query: 77 LHIAASAGRDEIVKALL--GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
AA G +V+ +L K VN V+ G L A E+ +LL+
Sbjct: 31 FLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARI 90
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKA-------------------STNIQDTEGN-- 173
D A+ A +KG ++++ +L + D +G
Sbjct: 91 GD-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRF 145
Query: 174 ----TPLHLACDEERVEEAKLLVSQGASI 198
TP+ LA ++ E +L+ +GA I
Sbjct: 146 SPDITPIILAAHCQKYEVVHMLLMKGARI 174
Score = 52.3 bits (124), Expect = 2e-07, Method: Composition-based stats.
Identities = 32/147 (21%), Positives = 52/147 (35%), Gaps = 31/147 (21%)
Query: 10 VCNLAYSGKLEELKESIL-ADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A G + +++ + + D + AL A H E+ E LL+
Sbjct: 31 FLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARI 90
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGA-------------------QVNAVNQNGC-- 107
D L +A S G IV+A+L A +++G
Sbjct: 91 GD-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRF 145
Query: 108 ----TPLHYAASKNRHEIAVMLLEGGA 130
TP+ AA ++E+ MLL GA
Sbjct: 146 SPDITPIILAAHCQKYEVVHMLLMKGA 172
Score = 37.3 bits (85), Expect = 0.006, Method: Composition-based stats.
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 30/115 (26%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
LA + E+ E +L ++LA D AL A S G+ IVE +L K
Sbjct: 65 ALQLAVGNEHLEVTELLLKKENLARIGD-----ALLLAISKGYVRIVEAILNHPGFAASK 119
Query: 70 -------------------DDAGW------SPLHIAASAGRDEIVKALLGKGAQV 99
D+ G +P+ +AA + E+V LL KGA++
Sbjct: 120 RLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARI 174
>2B0O-E nrPDB
Length = 301
Score = 61.9 bits (149), Expect = 2e-10, Method: Composition-based stats.
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 77 LHIAASAGR---DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
LH+A +V ++ G ++A +G T LHYAA N+ + +LL+G A
Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253
Query: 134 AKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHL 178
+ TA+ A K + + +L +A T PLH+
Sbjct: 254 TVNEAGETALDIARKKHHKECEELLEQAQAGTFA------FPLHV 292
Score = 61.2 bits (147), Expect = 4e-10, Method: Composition-based stats.
Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Query: 143 MHRAAAKGN---LKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
+H A N L ++ ++ + + +GNT LH A + + KLL+ A +
Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253
Query: 200 IENKEEKTPLQVAKGGLGLILKRMVE 225
N+ +T L +A+ + ++E
Sbjct: 254 TVNEAGETALDIARKKHHKECEELLE 279
Score = 60.8 bits (146), Expect = 4e-10, Method: Composition-based stats.
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 9/106 (8%)
Query: 109 PLHYA---ASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 165
LH A A++ + +++ G + DAK TA+H AA + +LL +A
Sbjct: 193 VLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALV 252
Query: 166 NIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 211
+ G T L +A + E +LL + PL V
Sbjct: 253 GTVNEAGETALDIARKKHHKECEELLEQ------AQAGTFAFPLHV 292
Score = 57.7 bits (138), Expect = 4e-09, Method: Composition-based stats.
Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 44 LHWA---CSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVN 100
LH A + +V+F++Q G ++ K G + LH AA + + +K LL A V
Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253
Query: 101 AVNQNGCTPLHYAASKNRHEIAVMLLEGGA 130
VN+ G T L A K+ E +L + A
Sbjct: 254 TVNEAGETALDIARKKHHKECEELLEQAQA 283
Score = 50.0 bits (118), Expect = 8e-07, Method: Composition-based stats.
Identities = 20/88 (22%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Query: 5 VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGV 64
+ + +A L L + I+ + D TALH+A + ++ LL+
Sbjct: 192 LVLHLAVKVANQASL-PLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRA 250
Query: 65 PVNDKDDAGWSPLHIAASAGRDEIVKAL 92
V ++AG + L IA E + L
Sbjct: 251 LVGTVNEAGETALDIARKKHHKECEELL 278
Score = 29.2 bits (64), Expect = 1.5, Method: Composition-based stats.
Identities = 18/73 (24%), Positives = 27/73 (36%), Gaps = 7/73 (9%)
Query: 7 NLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66
N + A + + LK +L ++L ++ TAL A H E E L Q
Sbjct: 227 NTALHYAALYNQPDCLK-LLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT 285
Query: 67 NDKDDAGWSPLHI 79
PLH+
Sbjct: 286 FAF------PLHV 292
>6C8G-A nrPDB
Length = 675
Score = 61.5 bits (148), Expect = 3e-10, Method: Composition-based stats.
Identities = 17/91 (18%), Positives = 29/91 (31%), Gaps = 17/91 (18%)
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT--------------EGNTPLHLACDE 182
+ TA+H A + + +L+ A + Q G PL LA
Sbjct: 101 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 160
Query: 183 ERVEEAKLLVS---QGASIYIENKEEKTPLQ 210
+ + L + A I ++ T L
Sbjct: 161 NQPDIVHYLTENAHKKADIRRQDSRGNTVLH 191
Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats.
Identities = 32/144 (22%), Positives = 50/144 (34%), Gaps = 33/144 (22%)
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD--------------HYEATAMHRAAAK 149
G T LH A + +L+E GA+ A+ ++ + AA
Sbjct: 101 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 160
Query: 150 GNLKMIHILLYY---KASTNIQDTEGNTPLH--LACDEERVEEAKLL-----------VS 193
++H L KA QD+ GNT LH +A + E K + V
Sbjct: 161 NQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVK 220
Query: 194 QGASIYIE---NKEEKTPLQVAKG 214
+E N + +PL +A
Sbjct: 221 LYPDSSLEAIFNNDSMSPLMMAAK 244
Score = 56.5 bits (135), Expect = 9e-09, Method: Composition-based stats.
Identities = 33/181 (18%), Positives = 61/181 (33%), Gaps = 36/181 (19%)
Query: 16 SGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA--- 72
+ K L+E I + +TALH A VE L++ G V+ +
Sbjct: 82 AEKTGNLREFINSPFRDVY---YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFF 138
Query: 73 -----------GWSPLHIAASAGRDEIVKALLGKG---AQVNAVNQNGCTPLH--YAASK 116
G PL +AA + +IV L A + + G T LH A +
Sbjct: 139 QPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIAD 198
Query: 117 NRHE-----------IAVMLLEGGANPDAKDHYEA---TAMHRAAAKGNLKMIHILLYYK 162
N E + + ++ + + + + + AA G + + ++ +
Sbjct: 199 NTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLE 258
Query: 163 A 163
Sbjct: 259 I 259
>6BBJ-A nrPDB
Length = 868
Score = 61.5 bits (148), Expect = 3e-10, Method: Composition-based stats.
Identities = 17/91 (18%), Positives = 29/91 (31%), Gaps = 17/91 (18%)
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT--------------EGNTPLHLACDE 182
+ TA+H A + + +L+ A + Q G PL LA
Sbjct: 232 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 291
Query: 183 ERVEEAKLLVS---QGASIYIENKEEKTPLQ 210
+ + L + A I ++ T L
Sbjct: 292 NQPDIVHYLTENAHKKADIRRQDSRGNTVLH 322
Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats.
Identities = 32/144 (22%), Positives = 50/144 (34%), Gaps = 33/144 (22%)
Query: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD--------------HYEATAMHRAAAK 149
G T LH A + +L+E GA+ A+ ++ + AA
Sbjct: 232 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 291
Query: 150 GNLKMIHILLYY---KASTNIQDTEGNTPLH--LACDEERVEEAKLL-----------VS 193
++H L KA QD+ GNT LH +A + E K + V
Sbjct: 292 NQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVK 351
Query: 194 QGASIYIE---NKEEKTPLQVAKG 214
+E N + +PL +A
Sbjct: 352 LYPDSSLEAIFNNDSMSPLMMAAK 375
Score = 56.5 bits (135), Expect = 9e-09, Method: Composition-based stats.
Identities = 33/181 (18%), Positives = 61/181 (33%), Gaps = 36/181 (19%)
Query: 16 SGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA--- 72
+ K L+E I + +TALH A VE L++ G V+ +
Sbjct: 213 AEKTGNLREFINSPFRDVY---YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFF 269
Query: 73 -----------GWSPLHIAASAGRDEIVKALLGKG---AQVNAVNQNGCTPLH--YAASK 116
G PL +AA + +IV L A + + G T LH A +
Sbjct: 270 QPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIAD 329
Query: 117 NRHE-----------IAVMLLEGGANPDAKDHYEA---TAMHRAAAKGNLKMIHILLYYK 162
N E + + ++ + + + + + AA G + + ++ +
Sbjct: 330 NTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLE 389
Query: 163 A 163
Sbjct: 390 I 390
>6MHW-A nrPDB
Length = 826
Score = 60.0 bits (144), Expect = 8e-10, Method: Composition-based stats.
Identities = 46/222 (20%), Positives = 78/222 (35%), Gaps = 45/222 (20%)
Query: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSA---GHTEIVEFLLQL-------G 63
E++ + ++ +T L A EIV LL G
Sbjct: 147 CRRRHDEDVPDFLMHK----LTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILG 202
Query: 64 VPVNDK----DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------- 105
+N + G + L+IA + +I L+ GA VNA +
Sbjct: 203 RFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYF 262
Query: 106 GCTPLHYAASKNRHEIAVMLLEGG-ANPDAKDHYEATAMHRAAAKGN---------LKMI 155
G TPL AA N+ EI +L+E + ++D +H +M
Sbjct: 263 GETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMY 322
Query: 156 HILLYYKAS---TNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
++L + ++ +G TPL LA + E K ++S+
Sbjct: 323 DMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364
Score = 52.3 bits (124), Expect = 2e-07, Method: Composition-based stats.
Identities = 35/178 (19%), Positives = 67/178 (37%), Gaps = 30/178 (16%)
Query: 13 LAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72
LA++ + + L I A+ T + +TAL+ A +I L+ G VN
Sbjct: 192 LAFAEENDILGRFINAEY---TEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKG 248
Query: 73 --------------GWSPLHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAA--- 114
G +PL +AA + EIV+ L+ + + + G LH
Sbjct: 249 AFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVA 308
Query: 115 --SKNRHEIAV------MLLEGGANPD-AKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
K +++ +L G + +++ T + AA G +++ +L +
Sbjct: 309 EDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREI 366
Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats.
Identities = 32/159 (20%), Positives = 48/159 (30%), Gaps = 32/159 (20%)
Query: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASK---NRHEIAVMLLEG--------- 128
DE V L ++ A + G T L A N EI +LL
Sbjct: 147 CRRRHDEDVPDFLMH--KLTASD-TGKTCLMKALLNINPNTKEIVRILLAFAEENDILGR 203
Query: 129 --GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT--------------EG 172
A + + TA++ A + + +L+ A N G
Sbjct: 204 FINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFG 263
Query: 173 NTPLHLACDEERVEEAKLLVSQ-GASIYIENKEEKTPLQ 210
TPL LA + E +LL+ I + L
Sbjct: 264 ETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILH 302
Score = 35.0 bits (79), Expect = 0.027, Method: Composition-based stats.
Identities = 25/139 (17%), Positives = 47/139 (33%), Gaps = 31/139 (22%)
Query: 114 ASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGN---LKMIHILLYY-------KA 163
+ E L T + +A N +++ ILL +
Sbjct: 147 CRRRHDEDVPDFLMHKL---TASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGR 203
Query: 164 STNIQDTE----GNTPLHLACDEERVEEAKLLVSQGASIYIENK--------------EE 205
N + TE G T L++A + + + A LL++ GA + K
Sbjct: 204 FINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFG 263
Query: 206 KTPLQVAKGGLGLILKRMV 224
+TPL +A + +++
Sbjct: 264 ETPLALAACTNQPEIVQLL 282
>4DX2-A nrPDB
Length = 259
Score = 59.2 bits (142), Expect = 1e-09, Method: Composition-based stats.
Identities = 51/230 (22%), Positives = 83/230 (36%), Gaps = 48/230 (20%)
Query: 18 KLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPL 77
L+ L +L K TD++ R S G T + + LL L N ++D L
Sbjct: 18 DLDGLLPFLLTHK--KRLTDEEFREP-----STGKTCLPKALLNLS---NGRNDTIPVLL 67
Query: 78 HIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD- 136
IA G + + + + G T LH A + +L+ GA+ A+
Sbjct: 68 DIAERTGNM---REFINSPFR--DIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQAR 122
Query: 137 -------------HYEATAMHRAAAKGNLKMIHILLYY---KASTNIQDTEGNTPLH--L 178
++ + AA +++ L KA QD+ GNT LH +
Sbjct: 123 GRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALV 182
Query: 179 ACDEERVEEAK-------LLVSQGA----SIYIE---NKEEKTPLQVAKG 214
A + E K LL+ + A +E N + +PL +A
Sbjct: 183 AIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAK 232
Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats.
Identities = 31/158 (19%), Positives = 54/158 (34%), Gaps = 33/158 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA--------------GWSPLHIAASA 83
+TALH A VE L+ G V+ + G PL +AA
Sbjct: 89 YRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 148
Query: 84 GRDEIVKALLGKG---AQVNAVNQNGCTPLH--YAASKNRHEIAV--------MLLEGG- 129
+ IV L A + + G T LH A + N E +LL+
Sbjct: 149 NQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCAR 208
Query: 130 --ANPDAK---DHYEATAMHRAAAKGNLKMIHILLYYK 162
+ + + ++ + + AA G + + ++ +
Sbjct: 209 LFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRRE 246
>6DJS-A nrPDB
Length = 676
Score = 59.2 bits (142), Expect = 2e-09, Method: Composition-based stats.
Identities = 32/147 (21%), Positives = 54/147 (36%), Gaps = 32/147 (21%)
Query: 79 IAASAGRDEIVKALL--GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
AA G +V+ +L K VN V+ G L A E+ +LL+ D
Sbjct: 50 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGD 109
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKA-------------------STNIQDTEGN---- 173
A+ A +KG ++++ +L + D +G
Sbjct: 110 -----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSP 164
Query: 174 --TPLHLACDEERVEEAKLLVSQGASI 198
TP+ LA ++ E +L+ +GA I
Sbjct: 165 DITPIILAAHCQKYEVVHMLLMKGARI 191
Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats.
Identities = 32/147 (21%), Positives = 52/147 (35%), Gaps = 31/147 (21%)
Query: 10 VCNLAYSGKLEELKESIL-ADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68
+ A G + +++ + + D + AL A H E+ E LL+
Sbjct: 48 FLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARI 107
Query: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGA-------------------QVNAVNQNGC-- 107
D L +A S G IV+A+L A +++G
Sbjct: 108 GD-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRF 162
Query: 108 ----TPLHYAASKNRHEIAVMLLEGGA 130
TP+ AA ++E+ MLL GA
Sbjct: 163 SPDITPIILAAHCQKYEVVHMLLMKGA 189
Score = 35.0 bits (79), Expect = 0.030, Method: Composition-based stats.
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 30/115 (26%)
Query: 10 VCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69
LA + E+ E +L ++LA D AL A S G+ IVE +L K
Sbjct: 82 ALQLAVGNEHLEVTELLLKKENLARIGD-----ALLLAISKGYVRIVEAILNHPGFAASK 136
Query: 70 -------------------DDAGW------SPLHIAASAGRDEIVKALLGKGAQV 99
D+ G +P+ +AA + E+V LL KGA++
Sbjct: 137 RLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARI 191
>3W9G-A nrPDB
Length = 260
Score = 58.8 bits (141), Expect = 2e-09, Method: Composition-based stats.
Identities = 17/91 (18%), Positives = 28/91 (30%), Gaps = 17/91 (18%)
Query: 137 HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT--------------EGNTPLHLACDE 182
+ TA+H A + + +L+ A + Q G PL LA
Sbjct: 91 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 150
Query: 183 ERVEEAKLLVSQG---ASIYIENKEEKTPLQ 210
+ L G A + ++ T L
Sbjct: 151 NQPHIVHYLTENGHKQADLRRQDSRGNTVLH 181
Score = 56.9 bits (136), Expect = 6e-09, Method: Composition-based stats.
Identities = 31/159 (19%), Positives = 56/159 (35%), Gaps = 33/159 (20%)
Query: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA--------------GWSPLHIAASA 83
+TALH A VE L++ G V+ + G PL +AA
Sbjct: 91 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 150
Query: 84 GRDEIVKALLGKG---AQVNAVNQNGCTPLH--YAASKNRHEIAV--------MLLEGG- 129
+ IV L G A + + G T LH A + N E +L++
Sbjct: 151 NQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAK 210
Query: 130 --ANPDAK---DHYEATAMHRAAAKGNLKMIHILLYYKA 163
+ + + ++ + + AA G + + ++ +
Sbjct: 211 LFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRREI 249
Score = 40.7 bits (94), Expect = 5e-04, Method: Composition-based stats.
Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 14/57 (24%)
Query: 171 EGNTPLHLACDEERVEEAKLLVSQGASIYIENK--------------EEKTPLQVAK 213
G T LH+A + +LLV +GA ++ + + + PL +A
Sbjct: 92 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAA 148
>6G1K-A nrPDB
Length = 921
Score = 58.5 bits (140), Expect = 3e-09, Method: Composition-based stats.
Identities = 32/137 (23%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 80 AASAGRDEIVKALLGKGA-----QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
A G VK L + +N ++ G T L A EI +LL
Sbjct: 39 AVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSF------ 92
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQ-------DTEGN------TPLHLACD 181
+ Y A+ A K + + +LL +K + + D + + TP+ LA
Sbjct: 93 -NVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAH 151
Query: 182 EERVEEAKLLVSQGASI 198
E K+LV +G S+
Sbjct: 152 TNNYEIIKMLVQKGVSV 168
Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats.
Identities = 32/140 (22%), Positives = 47/140 (33%), Gaps = 24/140 (17%)
Query: 10 VCNLAYSGKLEELKESILADKS----LATRTDQDSRTALHWACSAGHTEIVEFLLQLGVP 65
+ G +K ++ + D RTAL A + EI+E LL V
Sbjct: 36 YLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVY 95
Query: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKG------------AQVNAVNQN-GCTPLHY 112
V G + LH A V+ LL + TP+
Sbjct: 96 V------GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIIL 148
Query: 113 AASKNRHEIAVMLLEGGANP 132
AA N +EI ML++ G +
Sbjct: 149 AAHTNNYEIIKMLVQKGVSV 168
>4CJ9-A nrPDB
Length = 794
Score = 43.8 bits (102), Expect = 6e-05, Method: Composition-based stats.
Identities = 29/180 (16%), Positives = 70/180 (38%), Gaps = 7/180 (3%)
Query: 46 WACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 105
A + G + ++ +L+ +N++ + + IA + G + +KA+L A ++ +
Sbjct: 585 VAGNNGGAQALKAVLEHEATLNERGFSRADIVKIAGNGGGAQALKAVLEHEATLDERGFS 644
Query: 106 GCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAST 165
+ A + + +LE G + + + AA G + + +L + +
Sbjct: 645 RADIVRIAGNGGGAQALKAVLEHGPTLNERGFNLTDIVEMAANSGGAQALKAVLEHGPTL 704
Query: 166 NIQDTEGNTPLHLA--CDEERVEEAKLLVSQGASIYIENKEEKTPLQVA--KGGLGLILK 221
G + + + + K ++ G + + + + VA +GG G I K
Sbjct: 705 R---QRGLSLIDIVEIASNGGAQALKAVLKYGPVLMQAGRSNEEIVHVAARRGGAGRIRK 761
Score = 34.2 bits (77), Expect = 0.050, Method: Composition-based stats.
Identities = 22/148 (14%), Positives = 54/148 (36%), Gaps = 1/148 (0%)
Query: 79 IAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHY 138
IA + G + + A+L + + ++ A + + +LE A + +
Sbjct: 552 IAGNDGGTQALHAVLDLERMLGERGFSRADIVNVAGNNGGAQALKAVLEHEATLNERGFS 611
Query: 139 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
A + A G + + +L ++A+ + + + +A + + K ++ G ++
Sbjct: 612 RADIVKIAGNGGGAQALKAVLEHEATLDERGFSRADIVRIAGNGGGAQALKAVLEHGPTL 671
Query: 199 YIEN-KEEKTPLQVAKGGLGLILKRMVE 225
A G LK ++E
Sbjct: 672 NERGFNLTDIVEMAANSGGAQALKAVLE 699
>5Z96-A nrPDB
Length = 755
Score = 43.4 bits (101), Expect = 7e-05, Method: Composition-based stats.
Identities = 32/137 (23%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 80 AASAGRDEIVKALLGKGA-----QVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
A G VK L + +N ++ G T L A E+ +LL
Sbjct: 39 AVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSF------ 92
Query: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQ-------DTEGN------TPLHLACD 181
+ Y A+ A K + + +LL +K + + D + + TP+ LA
Sbjct: 93 -NVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAH 151
Query: 182 EERVEEAKLLVSQGASI 198
E KLLV +G S+
Sbjct: 152 TNNYEIIKLLVQKGVSV 168
Score = 31.9 bits (71), Expect = 0.22, Method: Composition-based stats.
Identities = 32/140 (22%), Positives = 49/140 (35%), Gaps = 24/140 (17%)
Query: 10 VCNLAYSGKLEELKESILADKS----LATRTDQDSRTALHWACSAGHTEIVEFLLQLGVP 65
N G +K+S+ + D RTAL A + E++E LL V
Sbjct: 36 YLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVY 95
Query: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAV-------NQN------GCTPLHY 112
V G + LH A V+ LL ++ TP+
Sbjct: 96 V------GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIIL 148
Query: 113 AASKNRHEIAVMLLEGGANP 132
AA N +EI +L++ G +
Sbjct: 149 AAHTNNYEIIKLLVQKGVSV 168
>6BWI-A nrPDB
Length = 977
Score = 36.5 bits (83), Expect = 0.010, Method: Composition-based stats.
Identities = 15/71 (21%), Positives = 28/71 (39%), Gaps = 5/71 (7%)
Query: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202
+ A A + + L+ + L A +R E +LL+S G S+
Sbjct: 198 LRLAVAWNRVDIAQSELFRG-DIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSL---- 252
Query: 203 KEEKTPLQVAK 213
TP+++A+
Sbjct: 253 GHFLTPMRLAQ 263
Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats.
Identities = 15/70 (21%), Positives = 28/70 (40%), Gaps = 5/70 (7%)
Query: 77 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136
L +A + R +I ++ L +G + + + L A +R E +L+ G +
Sbjct: 198 LRLAVAWNRVDIAQSELFRG-DIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHF- 255
Query: 137 HYEATAMHRA 146
T M A
Sbjct: 256 ---LTPMRLA 262
>1EV4-A nrPDB
Length = 221
Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats.
Identities = 10/43 (23%), Positives = 19/43 (44%), Gaps = 1/43 (2%)
Query: 171 EGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
G LH R+E + L++ A + + K ++P + K
Sbjct: 1 SGKPVLHYFNARGRMECIRFLLAA-AGVEFDEKFIQSPEDLEK 42
>2DI3-A nrPDB
Length = 239
Score = 29.2 bits (64), Expect = 1.7, Method: Composition-based stats.
Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
Query: 105 NGCTPLHYAASKNRHEIAVMLLEGGANPD--AKDHYEATA-MHRAAAKGNLK-MIHILLY 160
G LH +A + ++A LLE +P +D A H +KG +I L+
Sbjct: 106 EGWAALHSSAERGDWDVAEALLEKMDDPSLPLEDFLRFDAEFHVVISKGAENPLISTLME 165
>6GC1-A nrPDB
Length = 579
Score = 27.6 bits (60), Expect = 4.8, Method: Composition-based stats.
Identities = 11/44 (25%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLK 153
+ + A H+I +LL+ G P + + T + A GN +
Sbjct: 362 ILWIAMAGTHQIWALLLDSGKLPKKNELTKGTCLRFAG-SGNEE 404
>3WQO-A nrPDB
Length = 293
Score = 27.3 bits (59), Expect = 6.3, Method: Composition-based stats.
Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 4/73 (5%)
Query: 57 EFLLQLGVPVNDKDDAGWSPLHIAASAGRD-EIVKALLGKGA---QVNAVNQNGCTPLHY 112
E LL++ ++ K+ + A +AG E V+ L G V+A + NG H
Sbjct: 173 ESLLEIVKDIDSKNLGITFDIGHANTAGNPAEFVEKLQNIGIGIIHVHAHDNNGYDDEHL 232
Query: 113 AASKNRHEIAVML 125
+ +L
Sbjct: 233 KIGEGNINFIEVL 245
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.312 0.142 0.375
Lambda K H
0.267 0.0432 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,167,459
Number of Sequences: 36641
Number of extensions: 306607
Number of successful extensions: 2145
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 618
Number of HSP's gapped (non-prelim): 601
length of query: 226
length of database: 10,336,785
effective HSP length: 94
effective length of query: 132
effective length of database: 6,892,531
effective search space: 909814092
effective search space used: 909814092
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 57 (26.5 bits)