BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= O75365
         (173 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

1V3A-A nrPDB                                                          362   e-101
5LXQ-B nrPDB                                                          298   1e-81
1XM2-A nrPDB                                                          294   2e-80
3RZ2-A nrPDB                                                          289   3e-79
5K23-A nrPDB                                                          283   3e-77
5K22-A nrPDB                                                          281   1e-76
1ZCK-A nrPDB                                                          268   7e-73
3S4O-A nrPDB                                                          131   1e-31
1OHC-A nrPDB                                                           62   9e-11
5XW4-A nrPDB                                                           54   4e-08
5Z59-A nrPDB                                                           48   3e-06
3RO1-A nrPDB                                                           45   2e-05
4BPC-A nrPDB                                                           44   3e-05
5BZX-A nrPDB                                                           43   6e-05
1LAR-A nrPDB                                                           43   7e-05
4ERC-A nrPDB                                                           42   2e-04
3M4U-A nrPDB                                                           41   3e-04
4AZ1-A nrPDB                                                           38   0.002
6D3F-A nrPDB                                                           38   0.003
2JJD-A nrPDB                                                           37   0.003
5HDE-A nrPDB                                                           37   0.004
4YR8-G nrPDB                                                           37   0.006
1YN9-A nrPDB                                                           36   0.007
2C46-A nrPDB                                                           36   0.007
2R0B-A nrPDB                                                           36   0.008
2H03-A nrPDB                                                           36   0.010
2I75-A nrPDB                                                           34   0.027
1P15-A nrPDB                                                           34   0.034
1I9T-A nrPDB                                                           34   0.035
2B3O-A nrPDB                                                           33   0.049
1WRM-A nrPDB                                                           33   0.063
2PI7-A nrPDB                                                           33   0.066
3I36-A nrPDB                                                           33   0.086
4GE6-A nrPDB                                                           32   0.100
1WCH-A nrPDB                                                           32   0.11 
2RF6-A nrPDB                                                           32   0.12 
4BJO-A nrPDB                                                           32   0.16 
2Y96-A nrPDB                                                           32   0.18 
2GJT-A nrPDB                                                           32   0.19 
6DR7-A nrPDB                                                           32   0.21 
4OTK-A nrPDB                                                           32   0.21 
3RGQ-A nrPDB                                                           31   0.21 
2CFV-A nrPDB                                                           31   0.22 
1ZZW-A nrPDB                                                           31   0.24 
6H8S-A nrPDB                                                           31   0.24 
2OUD-A nrPDB                                                           31   0.25 
4JMK-A nrPDB                                                           31   0.29 
3V0J-A nrPDB                                                           31   0.29 
3PS5-A nrPDB                                                           30   0.45 
5OVR-A nrPDB                                                           30   0.48 
4HJQ-A nrPDB                                                           30   0.49 
2G6Z-A nrPDB                                                           30   0.55 
3S3F-A nrPDB                                                           30   0.60 
4PVG-A nrPDB                                                           30   0.79 
6CMQ-A nrPDB                                                           29   0.86 
4H1O-A nrPDB                                                           29   0.86 
2QEP-A nrPDB                                                           29   0.92 
3EZZ-A nrPDB                                                           29   1.3  
1RPM-A nrPDB                                                           28   1.6  
3F41-A nrPDB                                                           28   1.7  
5XJV-A nrPDB                                                           28   1.9  
6D67-A nrPDB                                                           28   2.0  
2A8B-A nrPDB                                                           28   2.0  
1M3G-A nrPDB                                                           28   2.4  
4IKC-A nrPDB                                                           28   2.6  
4KYQ-A nrPDB                                                           27   3.1  
2QLU-A nrPDB                                                           27   3.1  
2BZL-A nrPDB                                                           27   3.1  
2NV5-A nrPDB                                                           27   3.2  
1YFO-A nrPDB                                                           27   3.3  
2Q4E-A nrPDB                                                           27   3.5  
1ZC0-A nrPDB                                                           27   4.4  
3RFW-A nrPDB                                                           27   4.9  
6HS3-A nrPDB                                                           27   5.5  
3LJ8-A nrPDB                                                           26   6.8  
1UPI-A nrPDB                                                           26   7.3  
1PM7-A nrPDB                                                           26   7.8  
1Z2E-A nrPDB                                                           26   7.9  

>1V3A-A nrPDB
          Length = 173

 Score =  362 bits (930), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 173/173 (100%), Positives = 173/173 (100%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
Sbjct: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
Sbjct: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173
           ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173


>5LXQ-B nrPDB
          Length = 196

 Score =  298 bits (762), Expect = 1e-81,   Method: Compositional matrix adjust.
 Identities = 136/172 (79%), Positives = 152/172 (88%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 24  MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 83

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           +GI V+DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI
Sbjct: 84  EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 143

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
           E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+  CC+
Sbjct: 144 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 195


>1XM2-A nrPDB
          Length = 173

 Score =  294 bits (752), Expect = 2e-80,   Method: Compositional matrix adjust.
 Identities = 135/172 (78%), Positives = 151/172 (87%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 1   MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           +GI V+DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVH VAGLGRAPVLVALALI
Sbjct: 61  EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALI 120

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
           E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+  CC+
Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172


>3RZ2-A nrPDB
          Length = 189

 Score =  289 bits (740), Expect = 3e-79,   Method: Compositional matrix adjust.
 Identities = 134/168 (79%), Positives = 149/168 (88%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 21  MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 80

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           +GI V+DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI
Sbjct: 81  EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 140

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKT 168
           E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ 
Sbjct: 141 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRN 188


>5K23-A nrPDB
          Length = 189

 Score =  283 bits (724), Expect = 3e-77,   Method: Compositional matrix adjust.
 Identities = 131/169 (77%), Positives = 149/169 (88%), Gaps = 3/169 (1%)

Query: 4   MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
           MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+GI
Sbjct: 23  MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 82

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
            V+DWPFDDGAPPP ++V+DWL+L+K KF E PG CVAVHCVAGLGRAPVLVALALIE G
Sbjct: 83  HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 142

Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
           MKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H   CCV
Sbjct: 143 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCV 188


>5K22-A nrPDB
          Length = 183

 Score =  281 bits (718), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 127/165 (76%), Positives = 148/165 (89%)

Query: 2   ARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKD 61
           + MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+
Sbjct: 19  SHMNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKE 78

Query: 62  GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121
           GI V+DWPFDDGAPPP ++V+DWL+L+K KF E PG+ VAVHCVAGLGRAPVLVALALIE
Sbjct: 79  GIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAAVAVHCVAGLGRAPVLVALALIE 138

Query: 122 SGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTH 166
           +GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H
Sbjct: 139 AGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 183


>1ZCK-A nrPDB
          Length = 154

 Score =  268 bits (686), Expect = 7e-73,   Method: Compositional matrix adjust.
 Identities = 125/154 (81%), Positives = 138/154 (89%)

Query: 7   PAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVV 66
           PAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK+GI V+
Sbjct: 1   PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 60

Query: 67  DWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126
           DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALIE GMKY
Sbjct: 61  DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 120

Query: 127 EDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRF 160
           EDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF
Sbjct: 121 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 154


>3S4O-A nrPDB
          Length = 167

 Score =  131 bits (330), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 67/144 (46%), Positives = 90/144 (62%), Gaps = 7/144 (4%)

Query: 17  MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPP 76
             FLI   P+ + L T+I++L+  G   +VRVC  TYD T ++  GI V  WPFDDGAPP
Sbjct: 23  FHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSWPFDDGAPP 82

Query: 77  PGKVVEDWLSLVKAKFC------EAPGSCVAVHCVAGLGRAPVLVALALIESG-MKYEDA 129
              V++ WL L+  +          P   + VHCVAGLGRAP+LVALAL+E G +   DA
Sbjct: 83  TRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEYGNVSALDA 142

Query: 130 IQFIRQKRRGAINSKQLTYLEKYR 153
           I  IR+KR+GAIN  Q+ ++ KY+
Sbjct: 143 IALIREKRKGAINQTQMHWITKYK 166


>1OHC-A nrPDB
          Length = 348

 Score = 62.4 bits (150), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 6/119 (5%)

Query: 32  TFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91
           T+I+  K +  TT++R+ +  YD       G    D  F DG+ P   +V+++L +    
Sbjct: 209 TYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI---- 264

Query: 92  FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149
            CE     +AVHC AGLGR   L+A  +++   M   + I ++R  R G++   Q  +L
Sbjct: 265 -CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 322


>5XW4-A nrPDB
          Length = 415

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 7/128 (5%)

Query: 23  HNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVE 82
           + P  + L+ F  +        VVR+    Y+K   E  GI  +D  F+DG  P   +V+
Sbjct: 249 NQPFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVK 304

Query: 83  DWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAI 141
           +++    A+     G  +AVHC AGLGR   L+   LI + G    + I F+R  R G +
Sbjct: 305 NFVG--AAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMV 362

Query: 142 NSKQLTYL 149
              Q  +L
Sbjct: 363 VGPQQHWL 370


>5Z59-A nrPDB
          Length = 147

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 5/129 (3%)

Query: 18  RFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPP 77
           R   +  P    L     D        +V   E+ Y     EK G+ V+  P  D   P 
Sbjct: 11  RVAFSRMPAERELDEVARDFD--AVVVLVEDYELPYSLDEWEKRGVEVLHGPIPDFTAPS 68

Query: 78  GKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRA-PVLVALALIESGMKYEDAIQFIRQK 136
            + + + L  ++ +  E  G  V +HC+ GLGR+  V VA  +   G+   +A+  +R+K
Sbjct: 69  VEQLLEILRWIEERVRE--GKKVLIHCMGGLGRSGTVGVAWLMYSRGLSLREALMEVRRK 126

Query: 137 RRGAINSKQ 145
           R GA+ +++
Sbjct: 127 RPGAVETQE 135


>3RO1-A nrPDB
          Length = 161

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 7/116 (6%)

Query: 53  YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP 112
           Y  + L+K+G+  +  P  DG  P       +L+++K    E  G+ V  HCV G+GR  
Sbjct: 50  YYLSILKKNGLQPLHIPIPDGGVPSDS---QFLTIMKWLLSEKEGNLV--HCVGGIGRTG 104

Query: 113 VLVALALI-ESGMKYEDAIQFIRQKRRGAINS-KQLTYLEKYRPKQRLRFKDPHTH 166
            ++A  LI   G++ E AI  +R  R GA+ + +Q  +L +    ++   K+ +++
Sbjct: 105 TILASYLILTEGLEVESAIDEVRLVRPGAVQTYEQEMFLLRVEGMRKSWLKNIYSN 160


>4BPC-A nrPDB
          Length = 582

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 67  DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
           DWP + G P  G+   D++  V K K        ++VHC AG+GR  V + L+++   M+
Sbjct: 477 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 535

Query: 126 YEDAIQFIR 134
           YE  +   +
Sbjct: 536 YEGVVDIFQ 544


>5BZX-A nrPDB
          Length = 314

 Score = 43.1 bits (100), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 8/105 (7%)

Query: 65  VVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG- 123
           V  +PF+D  PP  ++++ +   +     E      A+HC AG GR  V++   L+  G 
Sbjct: 72  VAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGK 131

Query: 124 -MKYEDAIQF---IRQKRRGAI---NSKQLTYLEKYRPKQRLRFK 161
            +K ++A+ F   +R + +  +   + ++  Y   Y  K  L ++
Sbjct: 132 FLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYR 176


>1LAR-A nrPDB
          Length = 575

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 67  DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125
           DWP + G P  G+   D++  V K K        + VHC AG+GR  V + L+++   M+
Sbjct: 470 DWP-EQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR 528

Query: 126 YEDAIQFIR 134
           YE  +   +
Sbjct: 529 YEGVVDMFQ 537



 Score = 29.3 bits (64), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP D G P     +  +L  VKA      G  V VHC AG+GR    + +  +   MK+E
Sbjct: 182 WP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVIDAMLERMKHE 239

Query: 128 DAI 130
             +
Sbjct: 240 KTV 242


>4ERC-A nrPDB
          Length = 150

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 62  GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI- 120
           G+T+      D  PP    ++ ++ +V      A G  V VHC  G GR   ++A  L+ 
Sbjct: 55  GLTLHRLRIPDFCPPAPDQIDRFVQIVDE--ANARGEAVGVHCALGFGRTGTMLACYLVK 112

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQ 145
           E G+   DAI  IR+ R G+I + +
Sbjct: 113 ERGLAAGDAIAEIRRLRPGSIETYE 137


>3M4U-A nrPDB
          Length = 306

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 17/98 (17%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118
           +  V WP D G P      ++ LS++K     +P   + VHC AG+GR   L+    AL 
Sbjct: 192 VQYVGWP-DHGVPESAASFDELLSVIKNCVTTSP---ILVHCSAGIGRTGTLIGAYAALL 247

Query: 119 LIESGMKYEDAIQFI----RQKRRGAINSKQLTYLEKY 152
            IE G+  +  +  I    +QKR G +       LE+Y
Sbjct: 248 HIERGILTDSTVYSIVAAMKQKRFGMVQR-----LEQY 280


>4AZ1-A nrPDB
          Length = 302

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 12/97 (12%)

Query: 54  DKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPV 113
           D+ P +   +    WP D G P     +E  L+ VK      P   V VHC AG+GR   
Sbjct: 180 DEPPHKFTQVQYTGWP-DHGIPQSATSLEALLTNVKNSPTTVP---VVVHCSAGIGRTGT 235

Query: 114 LV----ALALIESGMKYE----DAIQFIRQKRRGAIN 142
           L+    AL  +E G   +    D +  +R++R G + 
Sbjct: 236 LIGAYAALTHLERGTLTDTTVYDVVSAMRRQRFGMVQ 272


>6D3F-A nrPDB
          Length = 279

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP + G P  GK + D ++ V+ +  +     + VHC AG GR    +AL+ I   +K E
Sbjct: 174 WP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAE 232

Query: 128 ---DAIQFIRQKR 137
              D  Q ++  R
Sbjct: 233 GLLDVFQAVKSLR 245


>2JJD-A nrPDB
          Length = 599

 Score = 37.4 bits (85), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP + G P  GK + D ++ V+ +  +     + VHC AG GR    +AL+ I   +K E
Sbjct: 490 WP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAE 548

Query: 128 ---DAIQFIRQKR 137
              D  Q ++  R
Sbjct: 549 GLLDVFQAVKSLR 561


>5HDE-A nrPDB
          Length = 307

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 11/89 (12%)

Query: 66  VDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL----ALIE 121
           V+WP D   P     + D +SL++ K+ E     + +HC AG GR   + A+     L++
Sbjct: 201 VNWP-DHDVPSSFDSILDMISLMR-KYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLK 258

Query: 122 SGMKYE-----DAIQFIRQKRRGAINSKQ 145
           +G   E     + IQ +R +R  A+ +K+
Sbjct: 259 AGKIPEEFNVFNLIQEMRTQRHSAVQTKE 287


>4YR8-G nrPDB
          Length = 167

 Score = 36.6 bits (83), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 94  EAPGSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137
           +A   CV VHC+AG+ R A + +A  +    M  ++A +F+++KR
Sbjct: 100 KASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKR 144


>1YN9-A nrPDB
          Length = 169

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 76  PPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIR 134
           PP  +V++++  VK    + PG  V VHC  G+ R   +V   L+ + G+  ++AI    
Sbjct: 92  PPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTGYMVCRYLMHTLGIAPQEAIDRFE 151

Query: 135 QKRRGAINSKQ 145
           + R   I  + 
Sbjct: 152 KARGHKIERQN 162


>2C46-A nrPDB
          Length = 241

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 28  ATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDD-GAPPPGKVVEDWL 85
           + LS +++ LK K G    +      YD+  +EK+GI  +       G  P  +  E ++
Sbjct: 70  SMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFI 129

Query: 86  SLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121
            L +      P   + VHC  G  R   L+   L+E
Sbjct: 130 RLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVE 165


>2R0B-A nrPDB
          Length = 154

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 13/125 (10%)

Query: 25  PTNATLSTFIEDLKKYGATTVVRV---CEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
           P ++ + + +  L+K+G T ++ +    E  + K   ++    +  +   D A  P + +
Sbjct: 17  PYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQ----LFRYLVLDIADNPVENI 72

Query: 82  EDWLSLVKAKFCEAP---GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137
             +  + K +F +     G  V VH  AG+ R+   V   ++E+ GMKY DA  ++ Q+R
Sbjct: 73  IRFFPMTK-EFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV-QER 130

Query: 138 RGAIN 142
           R  IN
Sbjct: 131 RFCIN 135


>2H03-A nrPDB
          Length = 291

 Score = 35.8 bits (81), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKY 126
           WP D G P   + +  ++  V+     +PG+    VHC AG+GR    +AL  I   +  
Sbjct: 189 WP-DHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDS 247

Query: 127 EDAI 130
           +D++
Sbjct: 248 KDSV 251


>2I75-A nrPDB
          Length = 320

 Score = 34.3 bits (77), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFC--EAPGSCVAVHCVAGLGRAPVLV----A 116
           I  + WP D G P       D++  V+ K    E P   V VHC AG+GR  VL+    A
Sbjct: 205 IQYIAWP-DHGVPDDSSDFLDFVCHVRNKRAGKEEP---VVVHCSAGIGRTGVLITMETA 260

Query: 117 LALIESGMKYE--DAIQFIRQKRRGAINS 143
           + LIE        D ++ +R +R   I +
Sbjct: 261 MCLIECNQPVYPLDIVRTMRDQRAMMIQT 289


>1P15-A nrPDB
          Length = 253

 Score = 33.9 bits (76), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP + G P  GK + + ++ V+ +  ++    + VHC AG GR     AL+ +   +K E
Sbjct: 148 WP-EVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAE 206

Query: 128 ---DAIQFIRQKR 137
              D  Q ++  R
Sbjct: 207 GILDVFQTVKSLR 219


>1I9T-A nrPDB
          Length = 210

 Score = 33.9 bits (76), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 28  ATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDD-GAPPPGKVVEDWL 85
           + LS +++ LK K      +      YD+  +EK+GI  +       G  P  +  E ++
Sbjct: 48  SMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFI 107

Query: 86  SLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121
            L +     +P   + VHC  G  R   L+   L+E
Sbjct: 108 RLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVE 143


>2B3O-A nrPDB
          Length = 532

 Score = 33.5 bits (75), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 13/90 (14%)

Query: 66  VDWPFDDGAPP-PGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALAL---- 119
           + WP D G P  PG V+  +L  +  +    P +  + VHC AG+GR   ++ + +    
Sbjct: 415 LSWP-DHGVPSEPGGVL-SFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMEN 472

Query: 120 -----IESGMKYEDAIQFIRQKRRGAINSK 144
                ++  +  +  IQ +R +R G + ++
Sbjct: 473 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTE 502


>1WRM-A nrPDB
          Length = 165

 Score = 33.1 bits (74), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 93  CEAPGSCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAIQFIRQKRRGAINS----KQLT 147
           C   G    VHC+AG+ R+  LV A  +  +   +EDA+  +R  R  A  +    +QL 
Sbjct: 79  CRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQ 138

Query: 148 YLEKYRPKQ 156
             EK+   Q
Sbjct: 139 EFEKHEVHQ 147


>2PI7-A nrPDB
          Length = 312

 Score = 33.1 bits (74), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 16/99 (16%)

Query: 33  FIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD------------WPFDDGAPPPG-- 78
           F ED   YG  TV  + E  +         I+  D            WP D G P     
Sbjct: 149 FTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWP-DHGVPTANAA 207

Query: 79  KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL 117
           + +  ++ +V+ K  ++ G  + +HC AG+GR    +AL
Sbjct: 208 ESILQFVQMVRQKSVKSKGPMI-IHCSAGVGRTGTFIAL 245


>3I36-A nrPDB
          Length = 342

 Score = 32.7 bits (73), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIESGMKY 126
           WP D G P    ++ ++  LV+    + P  S + VHC AG+GR    +A+  +   ++ 
Sbjct: 208 WP-DHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIEN 266

Query: 127 EDAI 130
           E+ +
Sbjct: 267 ENTV 270


>4GE6-A nrPDB
          Length = 314

 Score = 32.3 bits (72), Expect = 0.100,   Method: Compositional matrix adjust.
 Identities = 23/98 (23%), Positives = 41/98 (41%), Gaps = 15/98 (15%)

Query: 34  IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK-- 91
           +E++  Y  TT+      T ++   +      + WP D G P     + D+L +V+ +  
Sbjct: 161 VENMNHYKKTTLE--IHNTEERQKRQVTHFQFLSWP-DYGVPSSAASLIDFLRVVRNQQS 217

Query: 92  ------FCEAPGSC----VAVHCVAGLGRAPVLVALAL 119
                    + G C    + VHC AG+GR     +L +
Sbjct: 218 LAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDI 255


>1WCH-A nrPDB
          Length = 315

 Score = 32.3 bits (72), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 10/83 (12%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVL----VALALIESG 123
           WP  D    P    +D L+ +           +  HC AG+GR+  L    V L LI   
Sbjct: 214 WPDHDTPSQP----DDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQD 269

Query: 124 MKYE--DAIQFIRQKRRGAINSK 144
           + ++  D ++ +R +R G + ++
Sbjct: 270 LDFDISDLVRCMRLQRHGMVQTE 292


>2RF6-A nrPDB
          Length = 176

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 31/77 (40%), Gaps = 3/77 (3%)

Query: 48  VCEVTYDKTPLEKDGITVVDWPF-DDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVA 106
           V  +T DK  L    I ++  P  DD      K  +D  + +    C+     V VH  A
Sbjct: 60  VLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSK--CDQRNEPVLVHSAA 117

Query: 107 GLGRAPVLVALALIESG 123
           G+ R+  ++   L+   
Sbjct: 118 GVNRSGAMILAYLMSKN 134


>4BJO-A nrPDB
          Length = 338

 Score = 32.0 bits (71), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 26  TNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWL 85
           TN  L+   ED+K Y     + +  +T  +T  E        WP D G P       ++L
Sbjct: 155 TNLKLTLISEDIKSYYTVRQLELENLTTQETR-EILHFHYTTWP-DFGVPESPASFLNFL 212

Query: 86  SLVKAKFCEAPGSC-VAVHCVAGLGRA 111
             V+     +P    V VHC AG+GR+
Sbjct: 213 FKVRESGSLSPEHGPVVVHCSAGIGRS 239


>2Y96-A nrPDB
          Length = 219

 Score = 31.6 bits (70), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 8/60 (13%)

Query: 98  SCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAIQFIRQKR-----RGAINSKQLTYLEK 151
           S + VHCV G  R+  LV A  +I   M   DAIQ + + R     RG +  KQL  L+K
Sbjct: 140 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFL--KQLRELDK 197


>2GJT-A nrPDB
          Length = 295

 Score = 31.6 bits (70), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 16/99 (16%)

Query: 33  FIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD------------WPFDDGAPPPG-- 78
           F E+   YG  TV  + E   D        I   D            WP D G P     
Sbjct: 140 FTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWP-DHGVPTANAA 198

Query: 79  KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL 117
           + +  ++ +V+ +  ++ G  + +HC AG+GR    +AL
Sbjct: 199 ESILQFVHMVRQQATKSKGPMI-IHCSAGVGRTGTFIAL 236


>6DR7-A nrPDB
          Length = 306

 Score = 31.6 bits (70), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 23/115 (20%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLV------KAKFCEAPGSCVA---------VHCVAG 107
           + V  WP  D   P  +V +   SLV      K    E+ GS            +HC AG
Sbjct: 187 VHVTTWP--DFGVPESEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAG 244

Query: 108 LGRAPVLVALALI----ESGMKYEDAIQFIRQKRRGAINSK--QLTYLEKYRPKQ 156
           +GR   L+    +     S +  ED +  +R +R G +  K  QL  L K    Q
Sbjct: 245 VGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQ 299


>4OTK-A nrPDB
          Length = 318

 Score = 31.6 bits (70), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%)

Query: 41  GATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91
           G T     C  + D+  L+   + ++ WP    APP GK V+ W  +++++
Sbjct: 125 GFTRSQEACRASLDRLGLDYVDLYLIHWP----APPVGKYVDAWGGMIQSR 171


>3RGQ-A nrPDB
          Length = 156

 Score = 31.2 bits (69), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 2/61 (3%)

Query: 94  EAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRRG-AINSKQLTYLEK 151
           +A G CV VH  AG  R+  +VA  LI+      E+AI+ I + R   +I   QL  L++
Sbjct: 87  QALGQCVYVHSKAGRSRSATMVAAYLIQVHNWSPEEAIEAIAKIRSHISIRPSQLEVLKE 146

Query: 152 Y 152
           +
Sbjct: 147 F 147


>2CFV-A nrPDB
          Length = 316

 Score = 31.2 bits (69), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 71  DDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIESGMKYEDA 129
           D G P    ++ ++  LV+    ++P  S + VHC AG+GR    +A+  +   ++ E+ 
Sbjct: 210 DHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT 269

Query: 130 I 130
           +
Sbjct: 270 V 270


>1ZZW-A nrPDB
          Length = 149

 Score = 31.2 bits (69), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 97  GSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137
           G  + +HC AG+ R A +++A  +  + M   DA +F++ KR
Sbjct: 83  GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 124


>6H8S-A nrPDB
          Length = 301

 Score = 31.2 bits (69), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 13/86 (15%)

Query: 68  WPFD---DGAPPPGKVVEDWLSLVKAKFCEAPG-SCVAVHCVAGLGRAPVLVALALIESG 123
           WP     D APP   +V +   + +A   E P  S + VHC AG+GR    +A ++    
Sbjct: 197 WPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQ 253

Query: 124 MKYEDAIQF------IRQKRRGAINS 143
           ++ E  +        +RQ R G I +
Sbjct: 254 LRREGVVDILKTTCQLRQDRGGMIQT 279


>2OUD-A nrPDB
          Length = 177

 Score = 31.2 bits (69), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 97  GSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137
           G  + +HC AG+ R A +++A  +  + M   DA +F++ KR
Sbjct: 87  GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 128


>4JMK-A nrPDB
          Length = 152

 Score = 30.8 bits (68), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 26/43 (60%), Gaps = 2/43 (4%)

Query: 97  GSC-VAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137
            SC V VH +AG+ R A + +A  +   GM  +DA +F++ +R
Sbjct: 80  SSCQVIVHSLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRR 122


>3V0J-A nrPDB
          Length = 334

 Score = 30.8 bits (68), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 12/113 (10%)

Query: 45  VVRVC-EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVH 103
           +  +C E  YD+T  +     V+    DD   P    +  ++   K      P   +A+H
Sbjct: 69  IYNLCSERGYDETKFDNHVYRVM---IDDHNVPTLVDLLKFIDDAKVWMTSDPDHVIAIH 125

Query: 104 CVAGLGRAPVLVALALIESGMKYE---DAIQFIRQKR----RGAINSKQLTYL 149
              G GR   LV+  L+E G K++   +A+++   +R    +G   + Q+ Y+
Sbjct: 126 SKGGKGRTGTLVSSWLLEDG-KFDTAKEALEYFGSRRTDVFQGVETASQIRYV 177


>3PS5-A nrPDB
          Length = 595

 Score = 30.4 bits (67), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 13/90 (14%)

Query: 66  VDWPFDDGAPP-PGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALAL---- 119
           + WP D G P  PG V+  +L  +  +    P +  + VH  AG+GR   ++ + +    
Sbjct: 415 LSWP-DHGVPSEPGGVL-SFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMEN 472

Query: 120 -----IESGMKYEDAIQFIRQKRRGAINSK 144
                ++  +  +  IQ +R +R G + ++
Sbjct: 473 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTE 502


>5OVR-A nrPDB
          Length = 305

 Score = 30.0 bits (66), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 13/86 (15%)

Query: 68  WPFD---DGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESG 123
           WP     D APP   +V +   + +A   E P    + VHC AG+GR    +A ++    
Sbjct: 201 WPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQ 257

Query: 124 MKYEDAIQF------IRQKRRGAINS 143
           ++ E  +        +RQ R G I +
Sbjct: 258 LRQEGVVDILKTTCQLRQDRGGMIQT 283


>4HJQ-A nrPDB
          Length = 308

 Score = 30.0 bits (66), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 13/90 (14%)

Query: 66  VDWPFDDGAPP-PGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALAL---- 119
           + WP D G P  PG V+  +L  +  +    P +  + VH  AG+GR   ++ + +    
Sbjct: 195 LSWP-DHGVPSEPGGVL-SFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMEN 252

Query: 120 -----IESGMKYEDAIQFIRQKRRGAINSK 144
                ++  +  +  IQ +R +R G + ++
Sbjct: 253 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTE 282


>2G6Z-A nrPDB
          Length = 211

 Score = 30.0 bits (66), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 30/137 (21%), Positives = 57/137 (41%), Gaps = 24/137 (17%)

Query: 8   APVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVR------VCEVTYDKTPLEKD 61
            PVE+    + FL   +  +A+   F+ +L       V R      +  + Y   P+E  
Sbjct: 5   GPVEI----LPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLHYKWIPVEDS 60

Query: 62  GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121
               +   F +          D++  V+ K     G  V VH  AG+ R+P +    L++
Sbjct: 61  HTADISSHFQEAI--------DFIDCVREK-----GGKVLVHSEAGISRSPTICMAYLMK 107

Query: 122 S-GMKYEDAIQFIRQKR 137
           +   + ++A  +I+Q+R
Sbjct: 108 TKQFRLKEAFDYIKQRR 124


>3S3F-A nrPDB
          Length = 307

 Score = 30.0 bits (66), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP D G P P + +  ++   + +   A    + VHC AG+GR+   + L  I   +   
Sbjct: 208 WP-DFGVPNPPQTLVRFVRAFRDRI-GAEQRPIVVHCSAGVGRSGTFITLDRILQQINTS 265

Query: 128 DAIQF------IRQKRRGAINSKQ 145
           D +        +R++R   + ++Q
Sbjct: 266 DYVDIFGIVYAMRKERVWMVQTEQ 289


>4PVG-A nrPDB
          Length = 298

 Score = 29.6 bits (65), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 13/88 (14%)

Query: 68  WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALAL------ 119
           WP D G P  PG V+ D+L  V  K         V VHC AG+GR    + + +      
Sbjct: 185 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 242

Query: 120 ---IESGMKYEDAIQFIRQKRRGAINSK 144
              ++  +     IQ +R +R G + ++
Sbjct: 243 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 270


>6CMQ-A nrPDB
          Length = 427

 Score = 29.3 bits (64), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 13/88 (14%)

Query: 68  WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALAL------ 119
           WP D G P  PG V+ D+L  V  K         V VHC AG+GR    + + +      
Sbjct: 321 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 378

Query: 120 ---IESGMKYEDAIQFIRQKRRGAINSK 144
              ++  +     IQ +R +R G + ++
Sbjct: 379 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 406


>4H1O-A nrPDB
          Length = 560

 Score = 29.3 bits (64), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 13/88 (14%)

Query: 68  WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALAL------ 119
           WP D G P  PG V+ D+L  V  K         V VHC AG+GR    + + +      
Sbjct: 444 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 501

Query: 120 ---IESGMKYEDAIQFIRQKRRGAINSK 144
              ++  +     IQ +R +R G + ++
Sbjct: 502 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 529


>2QEP-A nrPDB
          Length = 304

 Score = 29.3 bits (64), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 10/84 (11%)

Query: 70  FDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALI----ESGM 124
           +D G P   + + D+    K   C    SC + VHC  G GR+   V + ++      G 
Sbjct: 199 YDRGVPSSSRSLLDFRR--KVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGA 256

Query: 125 KYED---AIQFIRQKRRGAINSKQ 145
           K  D    ++ +R +R G + +K+
Sbjct: 257 KEIDIAATLEHLRDQRPGMVQTKE 280


>3EZZ-A nrPDB
          Length = 144

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 81  VEDWLSLVKAKFCEAPGSC---VAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQK 136
           +  W  +   ++ +A   C   V VH  AG+ R A + +A  +++  ++ E+A +F++Q+
Sbjct: 63  ISSWF-MEAIEYIDAVKDCRGRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQR 121

Query: 137 R 137
           R
Sbjct: 122 R 122


>1RPM-A nrPDB
          Length = 278

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP D G P     +  ++  VK+K   + G  V VHC AG GR    + + ++    + E
Sbjct: 183 WP-DHGVPYHATGLLGFVRQVKSKSPPSAGPLV-VHCSAGAGRTGCFIVIDIMLDMAERE 240

Query: 128 ---DAIQFIRQKRRGAINSKQ 145
              D    +R+ R   +N  Q
Sbjct: 241 GVVDIYNCVRELRSRRVNMVQ 261


>3F41-A nrPDB
          Length = 629

 Score = 28.5 bits (62), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 15/69 (21%)

Query: 103 HCVAGLGRAPVLVALALIESGMK---YEDAIQFIRQKRRGAINSKQL----------TYL 149
           HC AG+GR  + + +  I    K   ++D IQ  RQK  G ++  ++           Y+
Sbjct: 238 HCYAGMGRTTIFMVMHDILKNAKDVSFDDIIQ--RQKLIGIVDLSEIPDKKKNYGRKAYI 295

Query: 150 EKYRPKQRL 158
           E+Y+  Q  
Sbjct: 296 ERYQFVQHF 304


>5XJV-A nrPDB
          Length = 185

 Score = 28.1 bits (61), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 93  CEAPGSCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAIQFIRQKR 137
              PG+ V VH V G+ R+  LV A  ++   +    A+  +RQ R
Sbjct: 118 LNTPGAKVLVHSVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHR 163


>6D67-A nrPDB
          Length = 520

 Score = 28.1 bits (61), Expect = 2.0,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 1/42 (2%)

Query: 97  GSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137
           G  V VH  AG+ R A + +A  +  + +K ++A +F++Q+R
Sbjct: 451 GGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRR 492


>2A8B-A nrPDB
          Length = 283

 Score = 28.1 bits (61), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 5/47 (10%)

Query: 100 VAVHCVAGLGRAPVLVALALIESGMKYE---DAIQFIRQKR--RGAI 141
           V VHC AG+GR    +A ++    +K E   DA+  + Q R  RG +
Sbjct: 212 VVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGM 258


>1M3G-A nrPDB
          Length = 145

 Score = 27.7 bits (60), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 24/122 (19%)

Query: 31  STFIEDLKKYGATTVVRVCE---------VTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
           S+ ++ L+  G T V+ V             Y   P+E + +  +   F +     G + 
Sbjct: 19  SSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI---GFI- 74

Query: 82  EDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGA 140
            DW+        +  G  V VH  AG+ R+  +    L++S  ++ ++A  F++Q RRG 
Sbjct: 75  -DWV--------KNSGGRVLVHSQAGISRSATICLAYLMQSRRVRLDEAFDFVKQ-RRGV 124

Query: 141 IN 142
           I+
Sbjct: 125 IS 126


>4IKC-A nrPDB
          Length = 281

 Score = 27.7 bits (60), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 18/99 (18%)

Query: 34  IEDLK--KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91
           I DLK  ++G    VR C  T               WP + G P     +  ++ LV+A 
Sbjct: 165 IRDLKIERHGDCMTVRQCNFTA--------------WP-EHGVPENSAPLIHFVKLVRAS 209

Query: 92  FCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAI 130
                   + VH  AG+GR  V +AL  +   +   D +
Sbjct: 210 RAHDTTPMI-VHSSAGVGRTGVFIALDHLTQHINDHDFV 247


>4KYQ-A nrPDB
          Length = 208

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/13 (84%), Positives = 11/13 (84%)

Query: 100 VAVHCVAGLGRAP 112
           V VHC AGLGRAP
Sbjct: 115 VYVHCSAGLGRAP 127


>2QLU-A nrPDB
          Length = 314

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 21/36 (58%)

Query: 123 GMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158
           GMK+E+ +QFI  ++RG+    +L  +  +  K  L
Sbjct: 65  GMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSL 100


>2BZL-A nrPDB
          Length = 325

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 29/131 (22%), Positives = 52/131 (39%), Gaps = 27/131 (20%)

Query: 39  KYGATTVVRVCEVTYDKTPLEKDGI-----------TVVDWPFDDGAPPPGKVVEDWLSL 87
           K+  TT  R   V Y  T L+   +              DWP D G P   +    +L  
Sbjct: 175 KFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWP-DHGCPEDVQGFLSYLEE 233

Query: 88  VKA------KFCEAPGSC---VAVHCVAGLGRAPVLVALALIESGMKYEDAIQ------F 132
           +++         E   +    + VHC AG+GR  VL+   L+   +++ + ++       
Sbjct: 234 IQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRL 293

Query: 133 IRQKRRGAINS 143
           +R++R   I +
Sbjct: 294 LREQRMFMIQT 304


>2NV5-A nrPDB
          Length = 299

 Score = 27.3 bits (59), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 4/64 (6%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKY 126
           WP D G P        +L  VK   C  P +  + VHC AG+GR    + +  +   +K+
Sbjct: 191 WP-DHGVPEHPTPFLAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKH 247

Query: 127 EDAI 130
           E  +
Sbjct: 248 EKTV 251


>1YFO-A nrPDB
          Length = 302

 Score = 27.3 bits (59), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 68  WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP D G P     +  +L  VKA   +  G+ V VHC AG+GR    V +  +   M  E
Sbjct: 198 WP-DFGVPFTPIGMLKFLKKVKACNPQYAGAIV-VHCSAGVGRTGTFVVIDAMLDMMHSE 255

Query: 128 ---DAIQFIRQKR 137
              D   F+ + R
Sbjct: 256 RKVDVYGFVSRIR 268


>2Q4E-A nrPDB
          Length = 362

 Score = 27.3 bits (59), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 15/27 (55%)

Query: 23  HNPTNATLSTFIEDLKKYGATTVVRVC 49
           HNP  A L  F+ D +++G    V+ C
Sbjct: 133 HNPRTALLKEFLSDSERFGQLKTVQSC 159


>1ZC0-A nrPDB
          Length = 309

 Score = 26.9 bits (58), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 23/102 (22%), Positives = 38/102 (37%), Gaps = 1/102 (0%)

Query: 15  KHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGA 74
           K + +  T   T       I+D+K+    TV R   + Y +       I    WP     
Sbjct: 152 KCVHYWPTEEETYGPFQIRIQDMKECPEYTV-RQLTIQYQEERRSVKHILFSAWPDHQTP 210

Query: 75  PPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA 116
              G ++     + ++    A    + VHC AG+GR    +A
Sbjct: 211 ESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIA 252


>3RFW-A nrPDB
          Length = 252

 Score = 26.9 bits (58), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 120 IESGMKYEDAIQFIRQKRRGAINSKQLTY 148
           IE+G+K+E+  + I QK +  +NS ++ Y
Sbjct: 223 IENGLKFEEFKKVINQKGQDLLNSAKVEY 251


>6HS3-A nrPDB
          Length = 260

 Score = 26.6 bits (57), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 3/40 (7%)

Query: 16 HMRFLITHNPTNATLSTFIEDLKK-YGATTVVRVCEVTYD 54
          HM  L    P   T S  + +LKK YG+ TVV+  +V+ D
Sbjct: 2  HMNALPNRQPAGTTSSLVVRNLKKRYGSRTVVK--DVSLD 39


>3LJ8-A nrPDB
          Length = 146

 Score = 26.2 bits (56), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 100 VAVHCVAGLGRA-PVLVALALIESGMKYEDAIQFIRQKR 137
           V VHC+AG+ R+  V VA  + +  +   DA   +++K+
Sbjct: 85  VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 123


>1UPI-A nrPDB
          Length = 225

 Score = 26.2 bits (56), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 4/38 (10%)

Query: 43  TTVVRVCEVTYD----KTPLEKDGITVVDWPFDDGAPP 76
           +TV+ +C   Y+     T    D    VDWP  DGA P
Sbjct: 148 STVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAP 185


>1PM7-A nrPDB
          Length = 202

 Score = 26.2 bits (56), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 4/38 (10%)

Query: 43  TTVVRVCEVTYD----KTPLEKDGITVVDWPFDDGAPP 76
           +TV+ +C   Y+     T    D    VDWP  DGA P
Sbjct: 128 STVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAP 165


>1Z2E-A nrPDB
          Length = 139

 Score = 26.2 bits (56), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 18/43 (41%)

Query: 42  ATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84
           A  VV +C    DK P+    +    W FDD A   G   E W
Sbjct: 75  ADLVVTLCGDAADKCPMTPPHVKREHWGFDDPARAQGTEEEKW 117


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

5LXQ-B nrPDB                                                          285   1e-77
1XM2-A nrPDB                                                          278   6e-76
3RZ2-A nrPDB                                                          274   1e-74
1V3A-A nrPDB                                                          274   1e-74
5K23-A nrPDB                                                          268   8e-73
5K22-A nrPDB                                                          265   6e-72
1ZCK-A nrPDB                                                          249   4e-67
3S4O-A nrPDB                                                          172   9e-44
5XW4-A nrPDB                                                          149   8e-37
5Z59-A nrPDB                                                          146   6e-36
1OHC-A nrPDB                                                          144   2e-35
3RO1-A nrPDB                                                          125   9e-30
5BZX-A nrPDB                                                          111   1e-25
4ERC-A nrPDB                                                          101   1e-22
4BPC-A nrPDB                                                           87   5e-18
1LAR-A nrPDB                                                           85   1e-17
3M4U-A nrPDB                                                           83   6e-17

Sequences not found previously or not previously below threshold:

4AZ1-A nrPDB                                                           69   9e-13
6D3F-A nrPDB                                                           69   9e-13
2JJD-A nrPDB                                                           69   1e-12
1P15-A nrPDB                                                           67   3e-12
3V0J-A nrPDB                                                           66   8e-12
2B3O-A nrPDB                                                           66   8e-12
2H03-A nrPDB                                                           65   1e-11
2C46-A nrPDB                                                           64   3e-11
1YN9-A nrPDB                                                           64   5e-11
1FPZ-A nrPDB                                                           62   2e-10
4HJQ-A nrPDB                                                           61   2e-10
3PS5-A nrPDB                                                           61   2e-10
1I9T-A nrPDB                                                           61   3e-10
3I36-A nrPDB                                                           60   5e-10
4GE6-A nrPDB                                                           60   6e-10
2NV5-A nrPDB                                                           58   2e-09
2BZL-A nrPDB                                                           58   2e-09
2CFV-A nrPDB                                                           57   4e-09
6D4D-A nrPDB                                                           57   4e-09
5OVR-A nrPDB                                                           57   4e-09
2A8B-A nrPDB                                                           57   4e-09
4BJO-A nrPDB                                                           57   5e-09
1L8K-A nrPDB                                                           57   6e-09
4H1O-A nrPDB                                                           56   8e-09
6CMQ-A nrPDB                                                           56   8e-09
2I75-A nrPDB                                                           56   9e-09
1RPM-A nrPDB                                                           55   1e-08
5HDE-A nrPDB                                                           55   1e-08
4PVG-A nrPDB                                                           55   1e-08
2GJT-A nrPDB                                                           55   2e-08
2QEP-A nrPDB                                                           55   2e-08
2PI7-A nrPDB                                                           55   2e-08
2I1Y-A nrPDB                                                           55   2e-08
1ZC0-A nrPDB                                                           54   3e-08
3OLR-A nrPDB                                                           53   6e-08
6H8S-A nrPDB                                                           53   6e-08
1WCH-A nrPDB                                                           52   1e-07
3S3F-A nrPDB                                                           52   1e-07
1YFO-A nrPDB                                                           52   1e-07
2C7S-A nrPDB                                                           52   2e-07
2OOQ-A nrPDB                                                           51   3e-07
1WRM-A nrPDB                                                           51   3e-07
4YR8-G nrPDB                                                           50   6e-07
1YGU-A nrPDB                                                           50   6e-07
2R0B-A nrPDB                                                           49   8e-07
4RHG-A nrPDB                                                           49   8e-07
4IKC-A nrPDB                                                           49   1e-06
2Q47-A nrPDB                                                           48   3e-06
4GFV-A nrPDB                                                           47   4e-06
5AWX-A nrPDB                                                           47   4e-06
4KYQ-A nrPDB                                                           47   5e-06
3F41-A nrPDB                                                           47   6e-06
2NLK-A nrPDB                                                           46   9e-06
2PBN-A nrPDB                                                           45   1e-05
3RGQ-A nrPDB                                                           45   2e-05
3LJ8-A nrPDB                                                           45   2e-05
2G6Z-A nrPDB                                                           44   3e-05
6N8N-Y nrPDB                                                           44   3e-05
4MBB-A nrPDB                                                           44   3e-05
1M3G-A nrPDB                                                           43   5e-05
4NX8-A nrPDB                                                           43   6e-05
6DR7-A nrPDB                                                           43   7e-05
4TVV-A nrPDB                                                           42   1e-04
1ZZW-A nrPDB                                                           42   1e-04
4B04-A nrPDB                                                           42   1e-04
5GTJ-A nrPDB                                                           42   1e-04
2OUD-A nrPDB                                                           42   1e-04
1J4X-A nrPDB                                                           41   2e-04
4JMK-A nrPDB                                                           41   3e-04
1G4W-R nrPDB                                                           41   3e-04
5M43-A nrPDB                                                           41   3e-04
5XJV-A nrPDB                                                           40   5e-04
2Y96-A nrPDB                                                           40   5e-04
1YZ4-A nrPDB                                                           40   6e-04
2RF6-A nrPDB                                                           40   6e-04
6I28-A nrPDB                                                           40   7e-04
6D67-A nrPDB                                                           39   0.001
4Y2E-A nrPDB                                                           39   0.001
2ESB-A nrPDB                                                           39   0.001
3EZZ-A nrPDB                                                           38   0.002
2M3V-A nrPDB                                                           38   0.002
3D1Q-A nrPDB                                                           37   0.003
2WGP-A nrPDB                                                           37   0.003
1MKP-A nrPDB                                                           37   0.005
4R0S-A nrPDB                                                           37   0.006
4R30-A nrPDB                                                           36   0.008
4RKK-A nrPDB                                                           36   0.009
6E3B-A nrPDB                                                           36   0.010
2HCM-A nrPDB                                                           34   0.028
5Y15-A nrPDB                                                           33   0.079
2OZ5-A nrPDB                                                           32   0.10 
5NCR-A nrPDB                                                           32   0.12 
4D3P-A nrPDB                                                           32   0.15 
2QFY-A nrPDB                                                           32   0.15 
4CBI-A nrPDB                                                           31   0.32 
5WSO-A nrPDB                                                           30   0.43 
5WX1-A nrPDB                                                           30   0.65 
4KI9-A nrPDB                                                           30   0.68 
5MIO-C nrPDB                                                           29   1.3  
2REO-A nrPDB                                                           28   1.7  
3R2N-A nrPDB                                                           28   2.2  
1KF9-A nrPDB                                                           28   2.7  
4PYH-A nrPDB                                                           27   3.5  
5A94-A nrPDB                                                           27   3.6  
6OIX-A nrPDB                                                           27   3.9  
1OBQ-A nrPDB                                                           27   5.1  

>5LXQ-B nrPDB
          Length = 196

 Score =  285 bits (728), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 136/172 (79%), Positives = 152/172 (88%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 24  MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 83

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           +GI V+DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI
Sbjct: 84  EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 143

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
           E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+  CC+
Sbjct: 144 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 195


>1XM2-A nrPDB
          Length = 173

 Score =  278 bits (712), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 135/172 (78%), Positives = 151/172 (87%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 1   MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           +GI V+DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVH VAGLGRAPVLVALALI
Sbjct: 61  EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALI 120

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
           E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+  CC+
Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172


>3RZ2-A nrPDB
          Length = 189

 Score =  274 bits (701), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 134/169 (79%), Positives = 149/169 (88%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK
Sbjct: 21  MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 80

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           +GI V+DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI
Sbjct: 81  EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 140

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTR 169
           E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+  
Sbjct: 141 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN 189


>1V3A-A nrPDB
          Length = 173

 Score =  274 bits (701), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 173/173 (100%), Positives = 173/173 (100%)

Query: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60
           MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
Sbjct: 1   MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
Sbjct: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173
           ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173


>5K23-A nrPDB
          Length = 189

 Score =  268 bits (685), Expect = 8e-73,   Method: Composition-based stats.
 Identities = 131/169 (77%), Positives = 149/169 (88%), Gaps = 3/169 (1%)

Query: 4   MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
           MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+GI
Sbjct: 23  MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 82

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
            V+DWPFDDGAPPP ++V+DWL+L+K KF E PG CVAVHCVAGLGRAPVLVALALIE G
Sbjct: 83  HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 142

Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172
           MKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H   CCV
Sbjct: 143 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCV 188


>5K22-A nrPDB
          Length = 183

 Score =  265 bits (678), Expect = 6e-72,   Method: Composition-based stats.
 Identities = 127/165 (76%), Positives = 148/165 (89%)

Query: 2   ARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKD 61
           + MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+
Sbjct: 19  SHMNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKE 78

Query: 62  GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121
           GI V+DWPFDDGAPPP ++V+DWL+L+K KF E PG+ VAVHCVAGLGRAPVLVALALIE
Sbjct: 79  GIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAAVAVHCVAGLGRAPVLVALALIE 138

Query: 122 SGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTH 166
           +GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H
Sbjct: 139 AGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 183


>1ZCK-A nrPDB
          Length = 154

 Score =  249 bits (636), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 125/154 (81%), Positives = 138/154 (89%)

Query: 7   PAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVV 66
           PAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK+GI V+
Sbjct: 1   PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 60

Query: 67  DWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126
           DWPFDDGAPP  ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALIE GMKY
Sbjct: 61  DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 120

Query: 127 EDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRF 160
           EDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF
Sbjct: 121 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 154


>3S4O-A nrPDB
          Length = 167

 Score =  172 bits (435), Expect = 9e-44,   Method: Composition-based stats.
 Identities = 67/144 (46%), Positives = 90/144 (62%), Gaps = 7/144 (4%)

Query: 17  MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPP 76
             FLI   P+ + L T+I++L+  G   +VRVC  TYD T ++  GI V  WPFDDGAPP
Sbjct: 23  FHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSWPFDDGAPP 82

Query: 77  PGKVVEDWLSLVKAKFC------EAPGSCVAVHCVAGLGRAPVLVALALIESG-MKYEDA 129
              V++ WL L+  +          P   + VHCVAGLGRAP+LVALAL+E G +   DA
Sbjct: 83  TRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEYGNVSALDA 142

Query: 130 IQFIRQKRRGAINSKQLTYLEKYR 153
           I  IR+KR+GAIN  Q+ ++ KY+
Sbjct: 143 IALIREKRKGAINQTQMHWITKYK 166


>5XW4-A nrPDB
          Length = 415

 Score =  149 bits (375), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 7/139 (5%)

Query: 22  THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81
            + P  + L+ F  +        VVR+    Y+K   E  GI  +D  F+DG  P   +V
Sbjct: 248 LNQPFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIV 303

Query: 82  EDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRRGA 140
           ++++    A+     G  +AVHC AGLGR   L+   LI   G    + I F+R  R G 
Sbjct: 304 KNFVG--AAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGM 361

Query: 141 INSKQLTYLEKYRPKQRLR 159
           +   Q  +L  ++   R  
Sbjct: 362 VVGPQQHWLYLHQNDFREW 380


>5Z59-A nrPDB
          Length = 147

 Score =  146 bits (367), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%)

Query: 18  RFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPP 77
           R   +  P    L     D        +V   E+ Y     EK G+ V+  P  D   P 
Sbjct: 11  RVAFSRMPAERELDEVARDFD--AVVVLVEDYELPYSLDEWEKRGVEVLHGPIPDFTAPS 68

Query: 78  GKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP-VLVALALIESGMKYEDAIQFIRQK 136
            + + + L  ++ +  E  G  V +HC+ GLGR+  V VA  +   G+   +A+  +R+K
Sbjct: 69  VEQLLEILRWIEERVRE--GKKVLIHCMGGLGRSGTVGVAWLMYSRGLSLREALMEVRRK 126

Query: 137 RRGAINSKQLTYLEK 151
           R GA+ +++   + K
Sbjct: 127 RPGAVETQEQMEVLK 141


>1OHC-A nrPDB
          Length = 348

 Score =  144 bits (363), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 8/135 (5%)

Query: 31  STFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKA 90
            T+I+  K +  TT++R+ +  YD       G    D  F DG+ P   +V+++L +   
Sbjct: 208 ETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI--- 264

Query: 91  KFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINSKQLTYL 149
             CE     +AVHC AGLGR   L+A  ++    M   + I ++R  R G++   Q  +L
Sbjct: 265 --CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 322

Query: 150 EKYRPKQRLRFKDPH 164
                +  L  +  +
Sbjct: 323 --VMKQTNLWLEGDY 335


>3RO1-A nrPDB
          Length = 161

 Score =  125 bits (314), Expect = 9e-30,   Method: Composition-based stats.
 Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 7/116 (6%)

Query: 53  YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP 112
           Y  + L+K+G+  +  P  DG  P       +L+++K    E  G+   VHCV G+GR  
Sbjct: 50  YYLSILKKNGLQPLHIPIPDGGVPSDSQ---FLTIMKWLLSEKEGN--LVHCVGGIGRTG 104

Query: 113 VLVALALI-ESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRLRFKDPHTH 166
            ++A  LI   G++ E AI  +R  R GA+ +  Q  +L +    ++   K+ +++
Sbjct: 105 TILASYLILTEGLEVESAIDEVRLVRPGAVQTYEQEMFLLRVEGMRKSWLKNIYSN 160


>5BZX-A nrPDB
          Length = 314

 Score =  111 bits (278), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 12/135 (8%)

Query: 36  DLKKYGATTVVRVC-EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCE 94
           D K      +  +C E  YD          V  +PF+D  PP  ++++ +   +     E
Sbjct: 45  DSKHKNHYKIYNLCAERHYDTAKFNCR---VAQYPFEDHNPPQLELIKPFCEDLDQWLSE 101

Query: 95  APGSCVAVHCVAGLGRAPVLVALALIESG--MKYEDAIQF---IRQKRRGAI---NSKQL 146
                 A+HC AG GR  V++   L+  G  +K ++A+ F   +R + +  +   + ++ 
Sbjct: 102 DDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRY 161

Query: 147 TYLEKYRPKQRLRFK 161
            Y   Y  K  L ++
Sbjct: 162 VYYYSYLLKNHLDYR 176


>4ERC-A nrPDB
          Length = 150

 Score =  101 bits (252), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 8/120 (6%)

Query: 30  LSTFIEDLKKYGATTVVRVCE--VTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSL 87
           L    + L   G   +V + E    +  +     G+T+      D  PP    ++ ++ +
Sbjct: 24  LPAHYQFLLDLGVRHLVSLTERGPPHSDSC---PGLTLHRLRIPDFCPPAPDQIDRFVQI 80

Query: 88  VKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINSKQL 146
           V      A G  V VHC  G GR   ++A  L+ E G+   DAI  IR+ R G+I + + 
Sbjct: 81  VDE--ANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQ 138


>4BPC-A nrPDB
          Length = 582

 Score = 86.7 bits (213), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 21/152 (13%)

Query: 9   PVEVSYKHMRFLITHNPTNATLSTFI-EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD 67
           P E S ++  F++        +  +I  + K   A           D            D
Sbjct: 429 PAERSARYQYFVVDPM-AEYNMPQYILREFKVTDAR----------DGQSRTVRQFQFTD 477

Query: 68  WPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126
           WP + G P  G+   D++  V K K        ++VHC AG+GR  V + L+++   M+Y
Sbjct: 478 WP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRY 536

Query: 127 EDAIQFI------RQKRRGAINSK-QLTYLEK 151
           E  +         R +R   + ++ +  +  +
Sbjct: 537 EGVVDIFQTVKMLRTQRPAMVQTEDEYQFAYQ 568



 Score = 55.1 bits (131), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 21/94 (22%), Positives = 34/94 (36%), Gaps = 8/94 (8%)

Query: 59  EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118
           E        WP D G P        +L  VK       G  + VHC AG+GR    + + 
Sbjct: 180 EVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTANPPDAG-PIVVHCSAGVGRTGAFIVID 237

Query: 119 LIESGMKYEDAIQ------FIRQKRRGAINSKQL 146
            +   +K E  +        +R +R   + ++  
Sbjct: 238 AMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQ 271


>1LAR-A nrPDB
          Length = 575

 Score = 85.2 bits (209), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 20/149 (13%)

Query: 9   PVEVSYKHMRFLITHNPTNATLSTFI-EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD 67
           P E S ++  F++        +  +I  + K   A           D            D
Sbjct: 422 PAERSARYQYFVVDPM-AEYNMPQYILREFKVTDAR----------DGQSRTIRQFQFTD 470

Query: 68  WPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126
           WP + G P  G+   D++  V K K        + VHC AG+GR  V + L+++   M+Y
Sbjct: 471 WP-EQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRY 529

Query: 127 EDAIQFI------RQKRRGAINSKQLTYL 149
           E  +         R +R   + ++    L
Sbjct: 530 EGVVDMFQTVKTLRTQRPAMVQTEDQYQL 558



 Score = 59.7 bits (143), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 9/100 (9%)

Query: 59  EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118
           E      + WP D G P     +  +L  VKA      G  V VHC AG+GR    + + 
Sbjct: 173 ELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVID 230

Query: 119 LIESGMKYEDAIQF------IRQKRRGAINSK-QLTYLEK 151
            +   MK+E  +        +R +R   + ++ Q  ++ +
Sbjct: 231 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE 270


>3M4U-A nrPDB
          Length = 306

 Score = 82.8 bits (203), Expect = 6e-17,   Method: Composition-based stats.
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 12/92 (13%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118
           +  V WP D G P      ++ LS++K     +P   + VHC AG+GR   L+    AL 
Sbjct: 192 VQYVGWP-DHGVPESAASFDELLSVIKNCVTTSP---ILVHCSAGIGRTGTLIGAYAALL 247

Query: 119 LIESGMKYEDAIQFI----RQKRRGAINSKQL 146
            IE G+  +  +  I    +QKR G +   + 
Sbjct: 248 HIERGILTDSTVYSIVAAMKQKRFGMVQRLEQ 279


>4AZ1-A nrPDB
          Length = 302

 Score = 69.4 bits (168), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 12/104 (11%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA---- 118
           +    WP D G P     +E  L+ VK      P   V VHC AG+GR   L+       
Sbjct: 189 VQYTGWP-DHGIPQSATSLEALLTNVKNSPTTVP---VVVHCSAGIGRTGTLIGAYAALT 244

Query: 119 LIESGMKYEDAIQFI----RQKRRGAINSKQLTYLEKYRPKQRL 158
            +E G   +  +  +    R++R G +   +  ++       RL
Sbjct: 245 HLERGTLTDTTVYDVVSAMRRQRFGMVQRMEQYFVIYLTLMCRL 288


>6D3F-A nrPDB
          Length = 279

 Score = 69.0 bits (167), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 8/99 (8%)

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
                  WP + G P  GK + D ++ V+ +  +     + VHC AG GR    +AL+ I
Sbjct: 167 RQFHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNI 225

Query: 121 ESGMKYED------AIQFIRQKRRGAINS-KQLTYLEKY 152
              +K E       A++ +R +R   + + +Q  +  K 
Sbjct: 226 LERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKV 264


>2JJD-A nrPDB
          Length = 599

 Score = 69.0 bits (167), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 8/99 (8%)

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
                  WP + G P  GK + D ++ V+ +  +     + VHC AG GR    +AL+ I
Sbjct: 483 RQFHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNI 541

Query: 121 ESGMKYED------AIQFIRQKRRGAINS-KQLTYLEKY 152
              +K E       A++ +R +R   + + +Q  +  K 
Sbjct: 542 LERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKV 580



 Score = 57.8 bits (138), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 23/103 (22%), Positives = 40/103 (38%), Gaps = 9/103 (8%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV------A 116
           +    WP D G P     +  +L  VK          + VHC AG+GR    +      A
Sbjct: 191 LHFTSWP-DFGVPFTPIGMLKFLKKVKT-LNPVHAGPIVVHCSAGVGRTGTFIVIDAMMA 248

Query: 117 LALIESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRL 158
           +   E  +   + +  IR +R   + +  Q T++ +   +  L
Sbjct: 249 MMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYL 291


>1P15-A nrPDB
          Length = 253

 Score = 67.1 bits (162), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 24/125 (19%), Positives = 50/125 (40%), Gaps = 10/125 (8%)

Query: 35  EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCE 94
           E+ + Y    ++           + +       WP + G P  GK + + ++ V+ +  +
Sbjct: 117 EECESYTVRDLLVTNTRENKSRQIRQ--FHFHGWP-EVGIPSDGKGMINIIAAVQKQQQQ 173

Query: 95  APGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQ------FIRQKRRGAINS-KQLT 147
           +    + VHC AG GR     AL+ +   +K E  +        +R +R   + + +Q  
Sbjct: 174 SGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYE 233

Query: 148 YLEKY 152
           +  K 
Sbjct: 234 FCYKV 238


>3V0J-A nrPDB
          Length = 334

 Score = 65.9 bits (159), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 5/107 (4%)

Query: 50  EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLG 109
           E  YD+T  +     V     DD   P    +  ++   K      P   +A+H   G G
Sbjct: 75  ERGYDETKFDN---HVYRVMIDDHNVPTLVDLLKFIDDAKVWMTSDPDHVIAIHSKGGKG 131

Query: 110 RAPVLVALALIESGM--KYEDAIQFIRQKRRGAINSKQLTYLEKYRP 154
           R   LV+  L+E G     ++A+++   +R       +     +Y  
Sbjct: 132 RTGTLVSSWLLEDGKFDTAKEALEYFGSRRTDVFQGVETASQIRYVG 178


>2B3O-A nrPDB
          Length = 532

 Score = 65.9 bits (159), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 21/98 (21%), Positives = 41/98 (41%), Gaps = 12/98 (12%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIES 122
             + WP D G P     V  +L  +  +    P    + VHC AG+GR   ++ + ++  
Sbjct: 413 QYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLME 471

Query: 123 GMKY---------EDAIQFIRQKRRGAINSK-QLTYLE 150
            +           +  IQ +R +R G + ++ Q  ++ 
Sbjct: 472 NISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509


>2H03-A nrPDB
          Length = 291

 Score = 65.1 bits (157), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 30/141 (21%), Positives = 52/141 (36%), Gaps = 19/141 (13%)

Query: 20  LITHNPTNATLSTF-IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPG 78
           LI    + + L  + I + K         +C                  WP D G P   
Sbjct: 149 LILQMLSESVLPEWTIREFK---------ICGEEQLDAHRLIRHFHYTVWP-DHGVPETT 198

Query: 79  KVVEDWLSLVKAKFCEAPG-SCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQF----- 132
           + +  ++  V+     +PG     VHC AG+GR    +AL  I   +  +D++       
Sbjct: 199 QSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVH 258

Query: 133 -IRQKRRGAINSK-QLTYLEK 151
            +R  R   + ++ Q  YL +
Sbjct: 259 DLRLHRVHMVQTECQYVYLHQ 279


>2C46-A nrPDB
          Length = 241

 Score = 64.0 bits (154), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 30/118 (25%), Positives = 47/118 (39%), Gaps = 3/118 (2%)

Query: 27  NATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFD-DGAPPPGKVVEDW 84
            + LS +++ LK K G    +      YD+  +EK+GI  +       G  P  +  E +
Sbjct: 69  PSMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETF 128

Query: 85  LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAI 141
           + L +      P   + VHC  G  R   L+   L+E      E A+    Q R   I
Sbjct: 129 IRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGI 186


>1YN9-A nrPDB
          Length = 169

 Score = 63.6 bits (153), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 1/96 (1%)

Query: 53  YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP 112
           YD     + G+            PP  +V++++  VK    + PG  V VHC  G+ R  
Sbjct: 69  YDGVHFLRAGLLYKKIQVPGQTLPPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTG 128

Query: 113 VLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLT 147
            +V   L+ + G+  ++AI    + R   I  +   
Sbjct: 129 YMVCRYLMHTLGIAPQEAIDRFEKARGHKIERQNYV 164


>1FPZ-A nrPDB
          Length = 212

 Score = 61.7 bits (148), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 34/153 (22%), Positives = 54/153 (35%), Gaps = 16/153 (10%)

Query: 27  NATLSTFIEDLKKYGATTVVRVCEV--------TYDKTPLEKDGITVVDWPFDDGAPPPG 78
              +    E+LK  G   +   C                 ++ GI     P  DG  P  
Sbjct: 57  RRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDI 116

Query: 79  KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE--SGMKYEDAIQFIRQK 136
               + +  +             +H   GLGR+ ++ A  L+     +  E AI  +R  
Sbjct: 117 ASCCEIMEELTTCLKNYR--KTLIHSYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDL 174

Query: 137 R-RGAINS-KQLTYLEKYRPKQ--RLRFKDPHT 165
           R  GAI + KQ  YL ++R K    L  +D  +
Sbjct: 175 RGSGAIQTIKQYNYLHEFRDKLAAHLSSRDSQS 207


>4HJQ-A nrPDB
          Length = 308

 Score = 61.3 bits (147), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 12/98 (12%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIES 122
             + WP D G P     V  +L  +  +    P    + VH  AG+GR   ++ + ++  
Sbjct: 193 QYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLME 251

Query: 123 GMKY---------EDAIQFIRQKRRGAINSK-QLTYLE 150
            +           +  IQ +R +R G + ++ Q  ++ 
Sbjct: 252 NISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 289


>3PS5-A nrPDB
          Length = 595

 Score = 61.3 bits (147), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 12/98 (12%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIES 122
             + WP D G P     V  +L  +  +    P    + VH  AG+GR   ++ + ++  
Sbjct: 413 QYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLME 471

Query: 123 GMKY---------EDAIQFIRQKRRGAINSK-QLTYLE 150
            +           +  IQ +R +R G + ++ Q  ++ 
Sbjct: 472 NISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509


>1I9T-A nrPDB
          Length = 210

 Score = 60.5 bits (145), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 3/118 (2%)

Query: 27  NATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFD-DGAPPPGKVVEDW 84
            + LS +++ LK K      +      YD+  +EK+GI  +       G  P  +  E +
Sbjct: 47  PSMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETF 106

Query: 85  LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAI 141
           + L +     +P   + VHC  G  R   L+   L+E      E A+    Q R   I
Sbjct: 107 IRLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGI 164


>3I36-A nrPDB
          Length = 342

 Score = 60.1 bits (144), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 21/99 (21%), Positives = 42/99 (42%), Gaps = 9/99 (9%)

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRAPVLVALAL 119
                  WP D G P    ++ ++  LV+    + P    + VHC AG+GR    +A+  
Sbjct: 201 RQFHFTSWP-DHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDR 259

Query: 120 IESGMKYEDAIQF------IRQKRRGAINSK-QLTYLEK 151
           +   ++ E+ +        +R  R   + ++ Q  +L +
Sbjct: 260 LIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQ 298


>4GE6-A nrPDB
          Length = 314

 Score = 59.7 bits (143), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 27/137 (19%)

Query: 34  IEDLKKYGATTVVRVCEVTYDKTPLEKDGITV---VDWPFDDGAPPPGKVVEDWLSLVKA 90
           +E++  Y  TT+       ++    +K  +T    + WP D G P     + D+L +V+ 
Sbjct: 161 VENMNHYKKTTL-----EIHNTEERQKRQVTHFQFLSWP-DYGVPSSAASLIDFLRVVRN 214

Query: 91  KFCEA------------PGSCVAVHCVAGLGRAPVL----VALALIES--GMKYEDAIQF 132
           +   A            P   + VHC AG+GR        + LA +E    +     +  
Sbjct: 215 QQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSR 274

Query: 133 IRQKRRGAINSKQLTYL 149
           +R +R  +I + +  Y 
Sbjct: 275 MRTQRAFSIQTPEQYYF 291


>2NV5-A nrPDB
          Length = 299

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 22/94 (23%), Positives = 35/94 (37%), Gaps = 8/94 (8%)

Query: 59  EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118
           E        WP D G P        +L  VK       G  V VHC AG+GR    + + 
Sbjct: 182 EVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNPPDAGPMV-VHCSAGVGRTGCFIVID 239

Query: 119 LIESGMKYEDAIQF------IRQKRRGAINSKQL 146
            +   +K+E  +        +R +R   + ++  
Sbjct: 240 AMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQ 273


>2BZL-A nrPDB
          Length = 325

 Score = 57.8 bits (138), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 21/107 (19%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKA---------KFCEAPGSCVAVHCVAGLGRAPV 113
           +   DWP D G P   +    +L  +++         +  +     + VHC AG+GR  V
Sbjct: 210 LQYTDWP-DHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGV 268

Query: 114 LVALALIESGMKYEDAIQ------FIRQKRRGAINS-KQLTYLEKYR 153
           L+   L+   +++ + ++       +R++R   I +  Q  ++ +  
Sbjct: 269 LILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVL 315


>2CFV-A nrPDB
          Length = 316

 Score = 57.0 bits (136), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 19/89 (21%), Positives = 41/89 (46%), Gaps = 8/89 (8%)

Query: 71  DDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRAPVLVALALIESGMKYEDA 129
           D G P    ++ ++  LV+    ++P    + VHC AG+GR    +A+  +   ++ E+ 
Sbjct: 210 DHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT 269

Query: 130 IQF------IRQKRRGAINSK-QLTYLEK 151
           +        +R  R   + ++ Q  +L +
Sbjct: 270 VDVYGIVYDLRMHRPLMVQTEDQYVFLNQ 298


>6D4D-A nrPDB
          Length = 292

 Score = 57.0 bits (136), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 23/103 (22%), Positives = 40/103 (38%), Gaps = 9/103 (8%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV------A 116
           +    WP D G P     +  +L  VK          + VHC AG+GR    +      A
Sbjct: 190 LHFTSWP-DFGVPFTPIGMLKFLKKVKT-LNPVHAGPIVVHCSAGVGRTGTFIVIDAMMA 247

Query: 117 LALIESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRL 158
           +   E  +   + +  IR +R   + +  Q T++ +   +  L
Sbjct: 248 MMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYL 290


>5OVR-A nrPDB
          Length = 305

 Score = 57.0 bits (136), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 17/108 (15%)

Query: 59  EKDGITVV---DWP---FDDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRA 111
           E+ G+       WP     D APP   +V +   + +A   E P    + VHC AG+GR 
Sbjct: 189 EERGLKHYWFTSWPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCAPIIVHCSAGIGRT 245

Query: 112 PVLVALALIESGMKYEDAIQF------IRQKRRGAINS-KQLTYLEKY 152
              +A ++    ++ E  +        +RQ R G I + +Q  ++   
Sbjct: 246 GCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV 293


>2A8B-A nrPDB
          Length = 283

 Score = 57.0 bits (136), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 23/121 (19%), Positives = 42/121 (34%), Gaps = 14/121 (11%)

Query: 34  IEDLKKYGATTVV-RVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKF 92
           + +   Y    +V +    T               WP D   P   + +   +  V+   
Sbjct: 150 VNECDNYTIRNLVLKQGSHTQHVKHY-----WYTSWP-DHKTPDSAQPLLQLMLDVEEDR 203

Query: 93  CEAPG-SCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQ------FIRQKRRGAINSKQ 145
             + G   V VHC AG+GR    +A ++    +K E  +        +R  R G + + +
Sbjct: 204 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE 263

Query: 146 L 146
            
Sbjct: 264 Q 264


>4BJO-A nrPDB
          Length = 338

 Score = 56.7 bits (135), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 12/132 (9%)

Query: 26  TNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWL 85
           TN  L+   ED+K Y     + +  +T  +T  E        WP D G P       ++L
Sbjct: 155 TNLKLTLISEDIKSYYTVRQLELENLTTQETR-EILHFHYTTWP-DFGVPESPASFLNFL 212

Query: 86  SLVKAKFCEAPG-SCVAVHCVAGLGRAPVL----VALALIESG-----MKYEDAIQFIRQ 135
             V+     +P    V VHC AG+GR+         L L++       +  +  +  +R+
Sbjct: 213 FKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRK 272

Query: 136 KRRGAINSKQLT 147
            R G I +    
Sbjct: 273 FRMGLIQTADQL 284


>1L8K-A nrPDB
          Length = 314

 Score = 56.7 bits (135), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 35  EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCE 94
           ED+K Y    ++++  +   +T           WP D G P       ++L  V+     
Sbjct: 148 EDVKSYYTVHLLQLENINSGETRTISH-FHYTTWP-DFGVPESPASFLNFLFKVRESGSL 205

Query: 95  APG-SCVAVHCVAGLGRAPVL----VALALIESG--MKYEDAIQFIRQKRRGAINSKQLT 147
            P      +HC AG+GR+         L L+E G  +  +  +  +R+ R G I +    
Sbjct: 206 NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQL 265


>4H1O-A nrPDB
          Length = 560

 Score = 56.3 bits (134), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 12/98 (12%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHCVAGLGRAPVLVALAL--- 119
               WP D G P     V D+L  V  K         V VHC AG+GR    + + +   
Sbjct: 440 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 498

Query: 120 ------IESGMKYEDAIQFIRQKRRGAINSK-QLTYLE 150
                 ++  +     IQ +R +R G + ++ Q  ++ 
Sbjct: 499 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 536


>6CMQ-A nrPDB
          Length = 427

 Score = 55.9 bits (133), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 12/98 (12%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHCVAGLGRAPVLVALAL--- 119
               WP D G P     V D+L  V  K         V VHC AG+GR    + + +   
Sbjct: 317 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 375

Query: 120 ------IESGMKYEDAIQFIRQKRRGAINSK-QLTYLE 150
                 ++  +     IQ +R +R G + ++ Q  ++ 
Sbjct: 376 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 413


>2I75-A nrPDB
          Length = 320

 Score = 55.9 bits (133), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 8/90 (8%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118
           I  + WP D G P       D++  V+ K        V VHC AG+GR  VL+    A+ 
Sbjct: 205 IQYIAWP-DHGVPDDSSDFLDFVCHVRNK-RAGKEEPVVVHCSAGIGRTGVLITMETAMC 262

Query: 119 LIESG--MKYEDAIQFIRQKRRGAINSKQL 146
           LIE    +   D ++ +R +R   I +   
Sbjct: 263 LIECNQPVYPLDIVRTMRDQRAMMIQTPSQ 292


>1RPM-A nrPDB
          Length = 278

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 21/94 (22%), Positives = 38/94 (40%), Gaps = 8/94 (8%)

Query: 59  EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118
           E        WP D G P     +  ++  VK+K   + G  V VHC AG GR    + + 
Sbjct: 174 EIRQFHFTGWP-DHGVPYHATGLLGFVRQVKSKSPPSAGPLV-VHCSAGAGRTGCFIVID 231

Query: 119 LIESGMKYEDAIQ------FIRQKRRGAINSKQL 146
           ++    + E  +        +R +R   + +++ 
Sbjct: 232 IMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQ 265


>5HDE-A nrPDB
          Length = 307

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 11/96 (11%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA----LA 118
              V+WP D   P     + D +SL++ K+ E     + +HC AG GR   + A      
Sbjct: 198 FHYVNWP-DHDVPSSFDSILDMISLMR-KYQEHEDVPICIHCSAGCGRTGAICAIDYTWN 255

Query: 119 LIESGMKYED-----AIQFIRQKRRGAINSKQLTYL 149
           L+++G   E+      IQ +R +R  A+ +K+   L
Sbjct: 256 LLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYEL 291


>4PVG-A nrPDB
          Length = 298

 Score = 55.1 bits (131), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 12/98 (12%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHCVAGLGRAPVLVALAL--- 119
               WP D G P     V D+L  V  K         V VHC AG+GR    + + +   
Sbjct: 181 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 239

Query: 120 ------IESGMKYEDAIQFIRQKRRGAINSK-QLTYLE 150
                 ++  +     IQ +R +R G + ++ Q  ++ 
Sbjct: 240 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 277


>2GJT-A nrPDB
          Length = 295

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 20/107 (18%), Positives = 47/107 (43%), Gaps = 11/107 (10%)

Query: 63  ITVVDWPFDDGAPPPG--KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
                WP D G P     + +  ++ +V+ +  ++ G  + +HC AG+GR    +AL  +
Sbjct: 182 FNYTAWP-DHGVPTANAAESILQFVHMVRQQATKSKGPMI-IHCSAGVGRTGTFIALDRL 239

Query: 121 ESGMKYEDAIQ------FIRQKRRGAINSKQLTYLEKYRPKQRLRFK 161
              ++  + +        +R  R   + +++  Y+  ++  Q +  K
Sbjct: 240 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ-YIFIHQCVQLMWMK 285


>2QEP-A nrPDB
          Length = 304

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 18/91 (19%), Positives = 37/91 (40%), Gaps = 9/91 (9%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122
              + W +D G P   + + D+   V   +       + VHC  G GR+   V + ++ +
Sbjct: 193 FHFLSW-YDRGVPSSSRSLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRSGTYVLIDMVLN 250

Query: 123 GMK-------YEDAIQFIRQKRRGAINSKQL 146
            M            ++ +R +R G + +K+ 
Sbjct: 251 KMAKGAKEIDIAATLEHLRDQRPGMVQTKEQ 281


>2PI7-A nrPDB
          Length = 312

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 18/92 (19%), Positives = 40/92 (43%), Gaps = 10/92 (10%)

Query: 63  ITVVDWPFDDGAPPPG--KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
                WP D G P     + +  ++ +V+ K  ++ G  + +HC AG+GR    +AL  +
Sbjct: 191 FNYTAWP-DHGVPTANAAESILQFVQMVRQKSVKSKGPMI-IHCSAGVGRTGTFIALDWL 248

Query: 121 ESGMKYEDAIQFI------RQKRRGAINSKQL 146
              ++  + +  +      R  R   + +++ 
Sbjct: 249 LQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQ 280


>2I1Y-A nrPDB
          Length = 301

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 9/91 (9%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122
              + WP + G P   + + D+   V   +       + VHC  G GR    + + ++ +
Sbjct: 192 FHFLSWPAE-GTPASTRPLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRTGTYILIDMVLN 249

Query: 123 GMK-------YEDAIQFIRQKRRGAINSKQL 146
            M            ++ +R +R G + SK  
Sbjct: 250 RMAKGVKEIDIAATLEHVRDQRPGLVRSKDQ 280


>1ZC0-A nrPDB
          Length = 309

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 25/112 (22%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 46  VRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHC 104
           VR   + Y +       I    WP D   P     +   ++ V+      A    + VHC
Sbjct: 182 VRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHC 240

Query: 105 VAGLGRAPVLVALALIESGMKYEDAIQF------IRQKRRGAINS-KQLTYL 149
            AG+GR    +A  +    +K    +        +R  R G I + +Q  +L
Sbjct: 241 SAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFL 292


>3OLR-A nrPDB
          Length = 313

 Score = 53.2 bits (126), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 23/123 (18%), Positives = 50/123 (40%), Gaps = 11/123 (8%)

Query: 36  DLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEA 95
           + +K  +  ++R  +V ++            +WP D   P     + + +  V+  + E 
Sbjct: 180 EAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDVR-CYQED 237

Query: 96  PGSCVAVHCVAGLGRAPVLVA----LALIESGMKYE-----DAIQFIRQKRRGAINSKQL 146
               + +H  AG GR  V+ A      L++ G+  E       I+ +R +R   + +++ 
Sbjct: 238 DSVPICIHSSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQ 297

Query: 147 TYL 149
             L
Sbjct: 298 YEL 300


>6H8S-A nrPDB
          Length = 301

 Score = 53.2 bits (126), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 14/94 (14%)

Query: 67  DWP---FDDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRAPVLVALALIES 122
            WP     D APP   +V +   + +A   E P    + VHC AG+GR    +A ++   
Sbjct: 196 SWPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQ 252

Query: 123 GMKYEDAIQF------IRQKRRGAINS-KQLTYL 149
            ++ E  +        +RQ R G I + +Q  ++
Sbjct: 253 QLRREGVVDILKTTCQLRQDRGGMIQTCEQYQFV 286


>1WCH-A nrPDB
          Length = 315

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 9/98 (9%)

Query: 71  DDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA----LALIESGMKY 126
            D   P     +D L+ +           +  HC AG+GR+  L+     L LI   + +
Sbjct: 215 PDHDTPS--QPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDF 272

Query: 127 E--DAIQFIRQKRRGAINSK-QLTYLEKYRPKQRLRFK 161
           +  D ++ +R +R G + ++ Q  +  +       R +
Sbjct: 273 DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQ 310


>3S3F-A nrPDB
          Length = 307

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 8/92 (8%)

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
                  WP D G P P + +  ++   + +        + VHC AG+GR+   + L  I
Sbjct: 201 RHFHFTTWP-DFGVPNPPQTLVRFVRAFRDRIGAEQ-RPIVVHCSAGVGRSGTFITLDRI 258

Query: 121 ESGMKYEDAIQFI------RQKRRGAINSKQL 146
              +   D +         R++R   + ++Q 
Sbjct: 259 LQQINTSDYVDIFGIVYAMRKERVWMVQTEQQ 290


>1YFO-A nrPDB
          Length = 302

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 24/103 (23%), Positives = 39/103 (37%), Gaps = 9/103 (8%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA------ 116
                WP D G P     +  +L  VKA   +  G  + VHC AG+GR    V       
Sbjct: 193 FHFTSWP-DFGVPFTPIGMLKFLKKVKACNPQYAG-AIVVHCSAGVGRTGTFVVIDAMLD 250

Query: 117 LALIESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRL 158
           +   E  +     +  IR +R   + +  Q  ++ +   +  L
Sbjct: 251 MMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL 293


>2C7S-A nrPDB
          Length = 313

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 18/91 (19%), Positives = 34/91 (37%), Gaps = 10/91 (10%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG-SCVAVHCVAGLGRAPVLVALALIE 121
                WP D G P     +  ++  VK      P    + VHC AG GR    + + ++ 
Sbjct: 202 FHFTGWP-DHGVPYHATGLLSFIRRVK--LSNPPSAGPIVVHCSAGAGRTGCYIVIDIML 258

Query: 122 SGMKYEDAIQF------IRQKRRGAINSKQL 146
              + E  +        +R +R   + +++ 
Sbjct: 259 DMAEREGVVDIYNCVKALRSRRINMVQTEEQ 289


>2OOQ-A nrPDB
          Length = 286

 Score = 50.9 bits (120), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 18/90 (20%), Positives = 33/90 (36%), Gaps = 8/90 (8%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122
                WP D G P     +  ++  VK          + VHC AG GR    +A+  +  
Sbjct: 180 FHFTSWP-DHGVPCYATGLLGFVRQVK-FLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLD 237

Query: 123 GMKYEDAIQ------FIRQKRRGAINSKQL 146
             + E  +        +R +R   + +++ 
Sbjct: 238 MAENEGVVDIFNCVRELRAQRVNLVQTEEQ 267


>1WRM-A nrPDB
          Length = 165

 Score = 50.9 bits (120), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 33/139 (23%), Positives = 55/139 (39%), Gaps = 13/139 (9%)

Query: 34  IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK-AKF 92
            E L K   T ++ V    +D      +G+  +  P  D   P   +   +   +K    
Sbjct: 25  AEQLSKNKVTHILSV----HDSARPMLEGVKYLCIPAAD--SPSQNLTRHFKESIKFIHE 78

Query: 93  CEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKR----RGAINSKQLT 147
           C   G    VHC+AG+ R+  LV   ++  +   +EDA+  +R  R          +QL 
Sbjct: 79  CRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQ 138

Query: 148 YLEKYRPKQ-RLRFKDPHT 165
             EK+   Q R   K+ + 
Sbjct: 139 EFEKHEVHQYRQWLKEEYG 157


>4YR8-G nrPDB
          Length = 167

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 19/104 (18%)

Query: 54  DKTPLEKDGITVV-----DWPFDDGAPPP--------GKVVEDWLSLVKAKF-----CEA 95
           +K  ++++GI  V       P  D  P              E  L  +          +A
Sbjct: 42  NKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKA 101

Query: 96  PGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRR 138
              CV VHC+AG+ R+  +    +++   M  ++A +F+++KR 
Sbjct: 102 SNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP 145


>1YGU-A nrPDB
          Length = 610

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 8/93 (8%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122
           I    WP D G P    ++      V A F       + VH  AG+GR    + +  +  
Sbjct: 191 IQFTSWP-DHGVPEDPHLLLKLRRRVNA-FSNFFSGPIVVHSSAGVGRTGTYIGIDAMLE 248

Query: 123 GMKYEDAIQF------IRQKRRGAINSKQLTYL 149
           G++ E+ +        +R++R   +  +    L
Sbjct: 249 GLEAENKVDVYGYVVKLRRQRCLMVQVEAQYIL 281



 Score = 40.1 bits (92), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 18/105 (17%), Positives = 38/105 (36%), Gaps = 17/105 (16%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS---------CVAVHCVAGLGRAPVL 114
              +W  +   P   K +   + +VK K  +   S          + +HC  G  +  + 
Sbjct: 498 QYTNWSVEQ-LPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIF 556

Query: 115 VALALIESGMKYEDAIQFI------RQKRRGAINS-KQLTYLEKY 152
            AL  +    + E+ +         R+ R G +++ +Q  +L   
Sbjct: 557 CALLNLLESAETEEVVDIFQVVKALRKARLGMVSTFEQYQFLYDV 601


>2R0B-A nrPDB
          Length = 154

 Score = 49.3 bits (116), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 25/117 (21%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 25  PTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84
           P ++ + + +  L+K+G T ++ + +   +   ++ +   +  +   D A  P + +  +
Sbjct: 17  PYSSAMKSKLPVLQKHGITHIICIRQNI-EANFIKPNFQQLFRYLVLDIADNPVENIIRF 75

Query: 85  LSLVKAKF--CEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRR 138
             + K         G  V VH  AG+ R+   V   ++E+ GMKY DA  +++++R 
Sbjct: 76  FPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRF 132


>4RHG-A nrPDB
          Length = 306

 Score = 49.3 bits (116), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 9/90 (10%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118
           +  V WP + G P       ++++ V++   ++    V VH  AG+GR  VLV    A+ 
Sbjct: 201 LQYVAWP-EHGVPDDSSDFLEFVNYVRSLRVDSE--PVLVHSSAGIGRTGVLVTMETAMC 257

Query: 119 LIESGMKY--EDAIQFIRQKRRGAINSKQL 146
           L E  +     D ++ +R +R   + +   
Sbjct: 258 LTERNLPIYPLDIVRKMRDQRAMMVQTSSQ 287


>4IKC-A nrPDB
          Length = 281

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 32/142 (22%), Positives = 54/142 (38%), Gaps = 25/142 (17%)

Query: 19  FLITHNPTNATLSTFIEDLK--KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPP 76
            +IT    +  +   I DLK  ++G    VR C  T               WP + G P 
Sbjct: 150 IVITKLMEDVQIDWTIRDLKIERHGDCMTVRQCNFT--------------AWP-EHGVPE 194

Query: 77  PGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQ----- 131
               +  ++ LV+A         + VH  AG+GR  V +AL  +   +   D +      
Sbjct: 195 NSAPLIHFVKLVRASRAHDTTPMI-VHSSAGVGRTGVFIALDHLTQHINDHDFVDIYGLV 253

Query: 132 -FIRQKRRGAINS-KQLTYLEK 151
             +R +R   + +  Q  +L +
Sbjct: 254 AELRSERMCMVQNLAQYIFLHQ 275


>2Q47-A nrPDB
          Length = 151

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 3/85 (3%)

Query: 37  LKKYGATTVVRVCEVTY---DKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFC 93
           L+  G  +++ +C   Y   +   L+ +GI +  +  +    P   + +  + +      
Sbjct: 29  LQTLGLRSIIYLCPEPYPESNLQFLKSNGIRLFQFGIEGNKEPFVNIPDHKIRMALKVLL 88

Query: 94  EAPGSCVAVHCVAGLGRAPVLVALA 118
           +     V +HC  G  R   LV   
Sbjct: 89  DEKNHPVLIHCKRGKHRTGCLVGCL 113


>4GFV-A nrPDB
          Length = 297

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 24/123 (19%), Positives = 48/123 (39%), Gaps = 12/123 (9%)

Query: 38  KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97
           K      ++R  +VT+ K       +  + WP D G P     +   +   + +   +  
Sbjct: 162 KWLNEDIMLRTLKVTFQKESRSVYQLQYMSWP-DRGVPSSPDHMLAMVEEAR-RLQGSGP 219

Query: 98  SCVAVHCVAGLGRAPVLVALALIESGMKYE---------DAIQFIRQKRRGAINS-KQLT 147
             + VH  AG GR  VL  +  +   +  +         D +  +R++R  A+ + +Q  
Sbjct: 220 EPLCVHSSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYR 279

Query: 148 YLE 150
           +L 
Sbjct: 280 FLY 282


>5AWX-A nrPDB
          Length = 298

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 21/89 (23%), Positives = 35/89 (39%), Gaps = 8/89 (8%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
               WP D G P     V  ++         A G  V VHC AG+GR    + L  +   
Sbjct: 193 HYTQWP-DMGVPEYSLPVLTFVRKAAYAKRHAVG-PVVVHCSAGVGRTGTYIVLDSMLQQ 250

Query: 124 MKYEDAIQF------IRQKRRGAINSKQL 146
           +++E  +        IR +R   + +++ 
Sbjct: 251 IQHEGTVNIFGFLKHIRSQRNYLVQTEEQ 279


>4KYQ-A nrPDB
          Length = 208

 Score = 46.6 bits (109), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 3/82 (3%)

Query: 59  EKDGITVVDWPFDDGAPPPG-KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRA-PVLVA 116
           ++ GI  +  P  D  P      +   +S ++    E  G  V VHC AGLGRA  V +A
Sbjct: 74  KELGIRHMRRPAKDFDPLSLRSQLPKAVSSLEWAVSEGKG-RVYVHCSAGLGRAPGVSIA 132

Query: 117 LALIESGMKYEDAIQFIRQKRR 138
                  M    A   +  KR 
Sbjct: 133 YMYWFCDMNLNTAYDTLVSKRP 154


>3F41-A nrPDB
          Length = 629

 Score = 46.6 bits (109), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 46  VRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCV 105
           V++  V  ++  +EK+G+        D   P    ++++++  +     A    +  HC 
Sbjct: 482 VKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANA---WLHFHCQ 538

Query: 106 AGLGRAPVLVALA 118
           AG GR    +A+ 
Sbjct: 539 AGAGRTTAYMAMY 551



 Score = 41.2 bits (95), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 29/146 (19%), Positives = 55/146 (37%), Gaps = 21/146 (14%)

Query: 28  ATLSTFIEDLKKYGAT---TVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84
           +T+ +      K         V   +V  ++  +++ G         D   P    V+ +
Sbjct: 163 STVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKF 222

Query: 85  LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG---MKYEDAIQFIRQKRRGAI 141
           L   K+       + +  HC AG+GR  + + +  I      + ++D IQ  RQK  G +
Sbjct: 223 LEFYKSL---PKDAWLHYHCYAGMGRTTIFMVMHDILKNAKDVSFDDIIQ--RQKLIGIV 277

Query: 142 ----------NSKQLTYLEKYRPKQR 157
                     N  +  Y+E+Y+  Q 
Sbjct: 278 DLSEIPDKKKNYGRKAYIERYQFVQH 303


>2NLK-A nrPDB
          Length = 627

 Score = 45.9 bits (107), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 18/89 (20%), Positives = 33/89 (37%), Gaps = 8/89 (8%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
               WP D G P     V  ++    +         V VHC AG+GR    + +  +   
Sbjct: 197 HYTQWP-DMGVPEYALPVLTFVRR-SSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQ 254

Query: 124 MKYEDAIQF------IRQKRRGAINSKQL 146
           +K +  +        IR +R   + +++ 
Sbjct: 255 IKDKSTVNVLGFLKHIRTQRNYLVQTEEQ 283


>2PBN-A nrPDB
          Length = 313

 Score = 45.5 bits (106), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 18/89 (20%), Positives = 33/89 (37%), Gaps = 8/89 (8%)

Query: 64  TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123
               WP D G P     V  ++    +         V VHC AG+GR    + +  +   
Sbjct: 205 HYTQWP-DMGVPEYALPVLTFVRR-SSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQ 262

Query: 124 MKYEDAIQF------IRQKRRGAINSKQL 146
           +K +  +        IR +R   + +++ 
Sbjct: 263 IKDKSTVNVLGFLKHIRTQRNYLVQTEEQ 291


>3RGQ-A nrPDB
          Length = 156

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 30/138 (21%), Positives = 47/138 (34%), Gaps = 7/138 (5%)

Query: 19  FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTY---DKTPLEKDGITVVDWPFDDGA- 74
            L+   P        + D    G  T+    E  +        +K G+  +     D   
Sbjct: 10  VLLGALPLKNMTRRLVLDENVRGVITMNEEYETRFLCNTSKEWKKAGVEQLRLSTVDMTG 69

Query: 75  PPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFI 133
            P    +   +    A   +A G CV VH  AG  R+  +VA  LI+      E+AI+ I
Sbjct: 70  VPTLANLHKGVQF--ALKYQALGQCVYVHSKAGRSRSATMVAAYLIQVHNWSPEEAIEAI 127

Query: 134 RQKRRGAINSKQLTYLEK 151
            + R           + K
Sbjct: 128 AKIRSHISIRPSQLEVLK 145


>3LJ8-A nrPDB
          Length = 146

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 21/107 (19%), Positives = 40/107 (37%), Gaps = 7/107 (6%)

Query: 34  IEDLKKYGATTVVRVCEVTYDKTPLEKDG-ITVVDWPFDDGAPPPGK-VVEDWLSLVKAK 91
           +E L K G   ++ V     +    EK+G       P  D           + +  +   
Sbjct: 21  LESLAKLGIRYILNVTPNLPN--FFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEA 78

Query: 92  FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137
                   V VHC+AG+ R+  +    L++   +   DA   +++K+
Sbjct: 79  LS--QNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 123


>2G6Z-A nrPDB
          Length = 211

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 27/132 (20%), Positives = 55/132 (41%), Gaps = 14/132 (10%)

Query: 8   APVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD 67
            PVE+    + FL   +  +A+   F+ +L     T ++ V   T +        +    
Sbjct: 5   GPVEI----LPFLYLGSAYHASKCEFLANLH---ITALLNVSRRTSEACMTH---LHYKW 54

Query: 68  WPFDD-GAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG-MK 125
            P +D          ++ +  +     E  G  V VH  AG+ R+P +    L+++   +
Sbjct: 55  IPVEDSHTADISSHFQEAIDFID-CVREK-GGKVLVHSEAGISRSPTICMAYLMKTKQFR 112

Query: 126 YEDAIQFIRQKR 137
            ++A  +I+Q+R
Sbjct: 113 LKEAFDYIKQRR 124


>6N8N-Y nrPDB
          Length = 364

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 25/159 (15%), Positives = 54/159 (33%), Gaps = 29/159 (18%)

Query: 17  MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDG-AP 75
           +R +I H P  A  +           T ++ V +       L + G T+ + P DD    
Sbjct: 24  IRPIIDHRPLGAEFN----------ITHILSVIKFQVIPEYLIRKGYTLKNIPIDDDDVT 73

Query: 76  PPGKVVEDWLSLVKAKF---------------CEAPGSCVAVHCVAGLGRAPVLVALALI 120
              +  ++    +                    +     V  HC AGL R+   +   L+
Sbjct: 74  DVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLM 133

Query: 121 ES-GMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158
              G+    A+  +++K+          ++E+    +++
Sbjct: 134 YRYGLSLSMAMHAVKRKKPS--VEPNENFMEQLHLFEKM 170


>4MBB-A nrPDB
          Length = 184

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 19/112 (16%), Positives = 39/112 (34%), Gaps = 3/112 (2%)

Query: 49  CEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVA 106
               Y K     + +  +         P  + +  +   V     E   +   + VH   
Sbjct: 72  YTQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHSTH 131

Query: 107 GLGRAPVLVALALIE-SGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQR 157
           GL R   L+   LI+  G++ +DAI+   + R   +  +      +  P ++
Sbjct: 132 GLNRTGYLICRYLIDVEGVRPDDAIELFNRCRGHCLERQNYIEDLQNGPIRK 183


>1M3G-A nrPDB
          Length = 145

 Score = 43.2 bits (100), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 15/89 (16%), Positives = 36/89 (40%), Gaps = 6/89 (6%)

Query: 63  ITVVDWPFDDG-APPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI- 120
                 P +D          ++ +  +     +  G  V VH  AG+ R+  +    L+ 
Sbjct: 48  FRYKSIPVEDNQMVEISAWFQEAIGFIDW--VKNSGGRVLVHSQAGISRSATICLAYLMQ 105

Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYL 149
              ++ ++A  F++Q+R   + S   +++
Sbjct: 106 SRRVRLDEAFDFVKQRR--GVISPNFSFM 132


>4NX8-A nrPDB
          Length = 293

 Score = 43.2 bits (100), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 17/80 (21%), Positives = 30/80 (37%), Gaps = 3/80 (3%)

Query: 56  TPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV 115
           + +   G   V     D   P    V+ ++  V+A       + V  HC AG GR    +
Sbjct: 161 SMIRTGGHQYVRLTVTDHVRPVDSEVDRFIESVRAL---PENAWVHFHCRAGKGRTTTFM 217

Query: 116 ALALIESGMKYEDAIQFIRQ 135
            L  +    K +   + I++
Sbjct: 218 VLYDMLKNAKTDSFEEIIKR 237


>6DR7-A nrPDB
          Length = 306

 Score = 43.2 bits (100), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 26/104 (25%), Positives = 38/104 (36%), Gaps = 21/104 (20%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG-------SCVA--------VHCVAG 107
           + V  WP  D   P  +V +   SLV                S VA        +HC AG
Sbjct: 187 VHVTTWP--DFGVPESEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAG 244

Query: 108 LGRAPVLVALALI----ESGMKYEDAIQFIRQKRRGAINSKQLT 147
           +GR   L+    +     S +  ED +  +R +R G +  K   
Sbjct: 245 VGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQ 288


>4TVV-A nrPDB
          Length = 314

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 14/59 (23%), Positives = 21/59 (35%), Gaps = 3/59 (5%)

Query: 60  KDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118
           K G         D   P    V+  ++L+K        +   VHC  G GR   + A+ 
Sbjct: 185 KKGFDYYRIFISDHRAPLDSEVDALVALIKN---NPEDTWYHVHCRGGKGRTTTVFAMF 240


>1ZZW-A nrPDB
          Length = 149

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 97  GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149
           G  + +HC AG+ R+  +V   L++   M   DA +F++ KR   I S  L ++
Sbjct: 83  GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 134


>4B04-A nrPDB
          Length = 160

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 20/106 (18%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 35  EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK--AKF 92
            +L++ G T V+      +  TP   +G+ +     +    P   +   + +      + 
Sbjct: 22  RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRA 81

Query: 93  CEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKR 137
              PG  + VH   G+ R+  LV   L+    +   +AI+ ++  R
Sbjct: 82  LSQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 127


>5GTJ-A nrPDB
          Length = 181

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 20/106 (18%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 35  EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK--AKF 92
            +L++ G T V+      +  TP   +G+ +     +    P   +   + +      + 
Sbjct: 43  RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRA 102

Query: 93  CEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKR 137
              PG  + VH   G+ R+  LV   L+    +   +AI+ ++  R
Sbjct: 103 LSQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 148


>2OUD-A nrPDB
          Length = 177

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 97  GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149
           G  + +HC AG+ R+  +V   L++   M   DA +F++ KR   I S  L ++
Sbjct: 87  GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 138


>1J4X-A nrPDB
          Length = 184

 Score = 41.2 bits (95), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 29/119 (24%), Positives = 45/119 (37%), Gaps = 9/119 (7%)

Query: 27  NATLSTFIEDLKKYGATTVVRVCE------VTYDKTPLEKDGITVVDWPFDDGAPPPGKV 80
           NA+++  I  L+K G T V+   E      V  +    +  GIT +    +D        
Sbjct: 40  NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSA 99

Query: 81  -VEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137
             E     +     +     V VH   G  R+P LV   L+    M  + A+  +RQ R
Sbjct: 100 YFERAADFIDQALAQK-NGRVLVHSREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNR 157


>4JMK-A nrPDB
          Length = 152

 Score = 40.9 bits (94), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 25/124 (20%), Positives = 48/124 (38%), Gaps = 33/124 (26%)

Query: 45  VVRVCEVTY--------DKTPLEKDGITVV-----DWPFDDGAPPPG-----------KV 80
           + R+    Y        +K  + ++GI+ V       P  D                 + 
Sbjct: 3   LTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEK 62

Query: 81  VEDWLS-----LVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIR 134
           +  WL      + KAK        V VH +AG+ R+  +    ++++ GM  +DA +F++
Sbjct: 63  LLPWLDKSIEFIDKAKLSS---CQVIVHSLAGISRSATIAIAYIMKTMGMSSDDAYRFVK 119

Query: 135 QKRR 138
            +R 
Sbjct: 120 DRRP 123


>1G4W-R nrPDB
          Length = 383

 Score = 40.9 bits (94), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 15/67 (22%), Positives = 26/67 (38%), Gaps = 10/67 (14%)

Query: 63  ITVVDWPFDDGAP-PPGKVVEDWLSLVKAKFCEAPGSCVA-------VHCVAGLGRAPVL 114
           + V +WP  D  P P    +E     VK           +       +HC+ G+GR   +
Sbjct: 274 LHVKNWP--DHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTM 331

Query: 115 VALALIE 121
            A  +++
Sbjct: 332 AAALVLK 338


>5M43-A nrPDB
          Length = 225

 Score = 40.9 bits (94), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 20/129 (15%), Positives = 44/129 (34%), Gaps = 24/129 (18%)

Query: 34  IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDD--------GAPPPGKVVEDWL 85
              +K++  T ++ V + T D+       +  +    DD          P   + ++  L
Sbjct: 23  ARLIKEHRITHILSVIDHTVDRENEAFRHVKHLSIDIDDMEDQDILIHLPKIVRFIDSGL 82

Query: 86  SLVKAKFCEA--PGSCVAVHCVAGLGRAPVLVALALIES----------GMKYEDAI--- 130
             +      A      V VHC  G  R+   +   L+             +  ++A+   
Sbjct: 83  RGIDPSDSSAVASPGVVLVHCAMGKSRSVTAIIAYLLWKYPYRFGKSDPNISAKEAVSRA 142

Query: 131 -QFIRQKRR 138
            +++R+ R 
Sbjct: 143 LEWVRETRP 151


>5XJV-A nrPDB
          Length = 185

 Score = 40.1 bits (92), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 20/89 (22%), Positives = 35/89 (39%), Gaps = 6/89 (6%)

Query: 50  EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLG 109
              +  + +   G+   D P  D +        D++     +    PG+ V VH V G+ 
Sbjct: 80  GPDFYGSSVSYLGVPAHDLPDFDISA-YFSSAADFIH----RALNTPGAKVLVHSVVGVS 134

Query: 110 RAPVLVALALI-ESGMKYEDAIQFIRQKR 137
           R+  LV   L+    +    A+  +RQ R
Sbjct: 135 RSATLVLAYLMLHQRLSLRQAVITVRQHR 163


>2Y96-A nrPDB
          Length = 219

 Score = 40.1 bits (92), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 13/95 (13%)

Query: 48  VCEVTYDKTP-LEKDGITVVDWPFDDGAP---PPGKVVEDWLSLVKAKFCEAPGSCVAVH 103
                Y +   ++  G+   D P  D +    P    ++  LS           S + VH
Sbjct: 94  DTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALS--------DDHSKILVH 145

Query: 104 CVAGLGRAPVLVALAL-IESGMKYEDAIQFIRQKR 137
           CV G  R+  LV   L I   M   DAIQ + + R
Sbjct: 146 CVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNR 180


>1YZ4-A nrPDB
          Length = 160

 Score = 39.7 bits (91), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 34  IEDLKKYG---ATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK- 89
            +DL + G    T ++ + E    +  L+   IT +  P  D   P   + + +   +  
Sbjct: 23  AKDLDQLGRNKITHIISIHESP--QPLLQD--ITYLRIPVAD--TPEVPIKKHFKECINF 76

Query: 90  AKFCEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRR 138
              C   G    VH  AG+ R+  +V   ++  +G+ + D ++ I+  R 
Sbjct: 77  IHCCRLNGGNCLVHSFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP 126


>2RF6-A nrPDB
          Length = 176

 Score = 39.7 bits (91), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 25/114 (21%), Positives = 44/114 (38%), Gaps = 11/114 (9%)

Query: 48  VCEVTYDKTPLEKDGITVVDWPF-DDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVA 106
           V  +T DK  L    I ++  P  DD      K  +D  + +    C+     V VH  A
Sbjct: 60  VLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSK--CDQRNEPVLVHSAA 117

Query: 107 GLGRAPVLVALALIESGMKYEDAIQFI------RQKRRGAINSK--QLTYLEKY 152
           G+ R+  ++   L+    +    + F+      R  R   + +   +   +EKY
Sbjct: 118 GVNRSGAMILAYLMSKNKESLPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKY 171


>6I28-A nrPDB
          Length = 168

 Score = 39.7 bits (91), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 21/124 (16%), Positives = 40/124 (32%), Gaps = 4/124 (3%)

Query: 33  FIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKF 92
           F+         +++        +     DG  +     DD          + L       
Sbjct: 33  FVRQNNVGCVVSLIDSDVAPIKRALYLPDGDHLHVHCEDDAKCGALADNLEMLFNYLWLK 92

Query: 93  CEAPGSCVAVHCVAGLGRAPVLVALALIESG-MKYEDAIQFIRQKRRGAINSKQLTYLEK 151
                  V +HC AG+ R+  L    ++ +  + YE A Q++  KR          ++E 
Sbjct: 93  IHNEHKTVLIHCHAGVSRSATLAIYYIMRTNQIDYEQAFQYVYGKR---AVHPSEHFVEL 149

Query: 152 YRPK 155
            + K
Sbjct: 150 LKGK 153


>6D67-A nrPDB
          Length = 520

 Score = 38.9 bits (89), Expect = 0.001,   Method: Composition-based stats.
 Identities = 17/88 (19%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 64  TVVDWPFDD-GAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-E 121
                P +D           + +  + +   +  G  V VH  AG+ R+  +    L+  
Sbjct: 419 QYKSIPVEDNHKADISSWFNEAIDFIDS--IKNAGGRVFVHSQAGISRSATICLAYLMRT 476

Query: 122 SGMKYEDAIQFIRQKRRGAINSKQLTYL 149
           + +K ++A +F++Q+R  +I S   +++
Sbjct: 477 NRVKLDEAFEFVKQRR--SIISPNFSFM 502


>4Y2E-A nrPDB
          Length = 149

 Score = 38.9 bits (89), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/104 (22%), Positives = 41/104 (39%), Gaps = 7/104 (6%)

Query: 37  LKKYGATTVVRVCEVTYDKTPLEKDG-ITVVDWPFDDGAPPPGKVV-EDWLSLVKAKFCE 94
           L KYG   ++ V     +    E  G  T    P  D           + +S +     +
Sbjct: 27  LGKYGIKYILNVTPNLPNA--FEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSK 84

Query: 95  APGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137
             G  V VH +AG+ R+  +    L++   +   DA  F+++K+
Sbjct: 85  KCG--VLVHSLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKK 126


>2ESB-A nrPDB
          Length = 188

 Score = 38.9 bits (89), Expect = 0.001,   Method: Composition-based stats.
 Identities = 19/94 (20%), Positives = 32/94 (34%), Gaps = 8/94 (8%)

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKF--CEAPGSCVAVHCVAGLGRAPVLVALA 118
           + I  +  P  D    P   + D+   +       E       +HC AG+ R+  L    
Sbjct: 62  EDIQYMQVPVADS---PNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118

Query: 119 LI-ESGMKYEDAIQFIRQKRRGAINSKQLTYLEK 151
           L+    M   DA  + +  R   I      + E+
Sbjct: 119 LMKYHAMSLLDAHTWTKSCRP--IIRPNSGFWEQ 150


>3EZZ-A nrPDB
          Length = 144

 Score = 38.2 bits (87), Expect = 0.002,   Method: Composition-based stats.
 Identities = 14/53 (26%), Positives = 32/53 (60%), Gaps = 3/53 (5%)

Query: 98  SCVAVHCVAGLGRAPVL-VALALIESGMKYEDAIQFIRQKRRGAINSKQLTYL 149
             V VH  AG+ R+  + +A  +++  ++ E+A +F++Q+R  +I S   +++
Sbjct: 82  GRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRR--SIISPNFSFM 132


>2M3V-A nrPDB
          Length = 193

 Score = 37.8 bits (86), Expect = 0.002,   Method: Composition-based stats.
 Identities = 11/58 (18%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 83  DWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA-LIESGMKYEDAIQFIRQKRRG 139
           + LS+++          V +HC  G  R  +  A+  ++  G   + A++ +++   G
Sbjct: 86  EVLSVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALEEMQRGGFG 143


>3D1Q-A nrPDB
          Length = 340

 Score = 37.4 bits (85), Expect = 0.003,   Method: Composition-based stats.
 Identities = 14/69 (20%), Positives = 28/69 (40%), Gaps = 3/69 (4%)

Query: 47  RVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVA 106
           RV +V  ++   E  G+        D   P  + ++ +L+  +        + +  HC A
Sbjct: 192 RVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTL---PQDAWLHFHCEA 248

Query: 107 GLGRAPVLV 115
           G+GR    +
Sbjct: 249 GVGRTTAFM 257


>2WGP-A nrPDB
          Length = 190

 Score = 37.4 bits (85), Expect = 0.003,   Method: Composition-based stats.
 Identities = 21/103 (20%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 37  LKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP 96
           L+  G T +V     T +           V  P  D    P  +  D ++  K       
Sbjct: 47  LQARGITCIV---NATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVAD-KIHSVSRK 102

Query: 97  GSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRR 138
                VHC AG+ R+  L    L++   +   +A  +++ +R 
Sbjct: 103 HGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 145


>1MKP-A nrPDB
          Length = 144

 Score = 36.6 bits (83), Expect = 0.005,   Method: Composition-based stats.
 Identities = 24/132 (18%), Positives = 46/132 (34%), Gaps = 14/132 (10%)

Query: 9   PVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDG-ITVVD 67
           PVE+    + FL      ++T    +E+    G   ++ V     +    E  G      
Sbjct: 4   PVEI----LPFLYLGCAKDSTNLDVLEEF---GIKYILNVTPNLPNL--FENAGEFKYKQ 54

Query: 68  WPFDDGAPPPGKVV-EDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMK 125
            P  D           + +S +           V VH +AG+ R+  +    L++   + 
Sbjct: 55  IPISDHWSQNLSQFFPEAISFIDE--ARGKNCGVLVHSLAGISRSVTVTVAYLMQKLNLS 112

Query: 126 YEDAIQFIRQKR 137
             DA   ++ K+
Sbjct: 113 MNDAYDIVKMKK 124


>4R0S-A nrPDB
          Length = 218

 Score = 36.6 bits (83), Expect = 0.006,   Method: Composition-based stats.
 Identities = 11/58 (18%), Positives = 25/58 (43%), Gaps = 1/58 (1%)

Query: 83  DWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA-LIESGMKYEDAIQFIRQKRRG 139
           + LS+++          V +HC  G  R  +  A+  ++  G   + A++ ++    G
Sbjct: 111 EVLSVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALEEMQHGGFG 168


>4R30-A nrPDB
          Length = 184

 Score = 35.8 bits (81), Expect = 0.008,   Method: Composition-based stats.
 Identities = 20/104 (19%), Positives = 34/104 (32%), Gaps = 8/104 (7%)

Query: 56  TPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV 115
               ++G+  +  P  D +      +      +     E  G  V VH  AG+GR+   V
Sbjct: 72  KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEK-GHIVYVHSNAGVGRSTAAV 130

Query: 116 A-LALIESGMKYEDAIQFIRQKRRG------AINSKQLTYLEKY 152
                   G        F+  KR        A+   Q  + +K+
Sbjct: 131 CGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALARAQEDFFQKF 174


>4RKK-A nrPDB
          Length = 332

 Score = 35.8 bits (81), Expect = 0.009,   Method: Composition-based stats.
 Identities = 20/104 (19%), Positives = 34/104 (32%), Gaps = 8/104 (7%)

Query: 56  TPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV 115
               ++G+  +  P  D +      +      +     E  G  V VH  AG+GR+   V
Sbjct: 222 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEK-GHIVYVHSNAGVGRSTAAV 280

Query: 116 A-LALIESGMKYEDAIQFIRQKRRG------AINSKQLTYLEKY 152
                   G        F+  KR        A+   Q  + +K+
Sbjct: 281 CGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALARAQEDFFQKF 324


>6E3B-A nrPDB
          Length = 169

 Score = 35.8 bits (81), Expect = 0.010,   Method: Composition-based stats.
 Identities = 17/128 (13%), Positives = 31/128 (24%)

Query: 25  PTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84
           P     S   E LK      ++       +   L+  GI +          P   +    
Sbjct: 23  PRQENFSFLHERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHL 82

Query: 85  LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSK 144
           L+             + +H   G  R   L+                  R+       + 
Sbjct: 83  LTKALEIVLNPANQPILIHSNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARAL 142

Query: 145 QLTYLEKY 152
              ++E Y
Sbjct: 143 DQQFIEMY 150


>2HCM-A nrPDB
          Length = 164

 Score = 34.3 bits (77), Expect = 0.028,   Method: Composition-based stats.
 Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 62  GITVVDWP-FDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           G+  +  P FDD A      +E   + ++A      G    V+C  G  R+  +    L+
Sbjct: 55  GVAELRVPVFDDPAEDLLTHLEPTCAAMEAAVR--DGGSCLVYCKNGRSRSAAVCTAYLM 112

Query: 121 -ESGMKYEDAIQFIRQKRR 138
              G   + A Q ++  R 
Sbjct: 113 RHRGHSLDRAFQMVKSARP 131


>5Y15-A nrPDB
          Length = 197

 Score = 32.8 bits (73), Expect = 0.079,   Method: Composition-based stats.
 Identities = 17/79 (21%), Positives = 30/79 (37%), Gaps = 4/79 (5%)

Query: 62  GITVVDWP-FDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
           G+  +  P FDD A      +E   + ++A      G    V+   G  R+  +    L+
Sbjct: 83  GVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVR--AGGACLVYSKNGRSRSAAVCTAYLM 140

Query: 121 -ESGMKYEDAIQFIRQKRR 138
              G+    A Q ++  R 
Sbjct: 141 RHRGLSLAKAFQMVKSARP 159


>2OZ5-A nrPDB
          Length = 296

 Score = 32.4 bits (72), Expect = 0.10,   Method: Composition-based stats.
 Identities = 16/60 (26%), Positives = 24/60 (40%), Gaps = 10/60 (16%)

Query: 95  APGSCVAVHCVAGLGRAPVLVALALIESG----------MKYEDAIQFIRQKRRGAINSK 144
           A G  V  HC AG  R   +VAL L   G          ++  D++  +R +    I  +
Sbjct: 171 AAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQR 230


>5NCR-A nrPDB
          Length = 181

 Score = 32.0 bits (71), Expect = 0.12,   Method: Composition-based stats.
 Identities = 15/70 (21%), Positives = 24/70 (34%), Gaps = 1/70 (1%)

Query: 61  DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120
            GIT    P  D        +   L  + A+  EA      VH VAG+ R+       ++
Sbjct: 70  AGITAYHIPLRDDDKTNIASIMPALVKLLARL-EAEQKPTLVHSVAGVNRSGAAAMGYVM 128

Query: 121 ESGMKYEDAI 130
              +     +
Sbjct: 129 HKRLAENPTM 138


>4D3P-A nrPDB
          Length = 147

 Score = 32.0 bits (71), Expect = 0.15,   Method: Composition-based stats.
 Identities = 17/107 (15%), Positives = 37/107 (34%), Gaps = 18/107 (16%)

Query: 50  EVTYDKTPLEKDGITVV--------DWPFDDGAPPPGKVVE----DWLSLVKAKF----- 92
           +  +D   L+K+ +T +        +    D       +++    + LS     F     
Sbjct: 21  DAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEE 80

Query: 93  CEAPGSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKRR 138
            +     V VH  AG+ R A +++   +      +  A   ++  R 
Sbjct: 81  AKRKDGVVLVHANAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARP 127


>2QFY-A nrPDB
          Length = 427

 Score = 32.0 bits (71), Expect = 0.15,   Method: Composition-based stats.
 Identities = 25/131 (19%), Positives = 45/131 (34%), Gaps = 8/131 (6%)

Query: 1   MARMNRPAPVE-VSYKHMRFLITH--NPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTP 57
           MA  N    +E  ++   +  I    N   +T +T ++            V E  Y K+ 
Sbjct: 196 MAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQY-KSK 254

Query: 58  LEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL 117
            E+ GI       DD      K    ++  +K    +     VA     G G   ++ ++
Sbjct: 255 FEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVA----QGFGSLGLMTSI 310

Query: 118 ALIESGMKYED 128
            +   G  +E 
Sbjct: 311 LVTPDGKTFES 321


>4CBI-A nrPDB
          Length = 516

 Score = 30.8 bits (68), Expect = 0.32,   Method: Composition-based stats.
 Identities = 17/95 (17%), Positives = 33/95 (34%), Gaps = 9/95 (9%)

Query: 1   MARMNRPAPVEVSYKHMR----FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKT 56
           MAR + P P++++Y         L           T+ ++     A  +          T
Sbjct: 415 MARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDTY-DNYTFLNARKLGDDVPPYVYAT 473

Query: 57  PLEKDGITV--VDWPFD--DGAPPPGKVVEDWLSL 87
             E   + +  +DWP     G    G+ ++  + L
Sbjct: 474 EDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGL 508


>5WSO-A nrPDB
          Length = 476

 Score = 30.5 bits (67), Expect = 0.43,   Method: Composition-based stats.
 Identities = 17/94 (18%), Positives = 32/94 (34%), Gaps = 8/94 (8%)

Query: 1   MARMNRPAPVEVSYKHMR----FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKT 56
           MAR + P P++++Y         L           T+ E+     A  +     V    T
Sbjct: 383 MARTDHPEPIQLAYNSYEVQVPVLFPKIRNGEVTDTY-ENYSFLNARKLGEDVPVYIYAT 441

Query: 57  PLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKA 90
             E   + ++   + D   P  + V +    +K 
Sbjct: 442 EDEDLAVDLLGLDWPD---PGNQQVVETGKALKQ 472


>5WX1-A nrPDB
          Length = 733

 Score = 29.7 bits (65), Expect = 0.65,   Method: Composition-based stats.
 Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 9/95 (9%)

Query: 1   MARMNRPAPVEVSYKHMR----FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKT 56
           MAR + P P++++Y         L           ++ ++     A  +          T
Sbjct: 640 MARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDSY-DNYTFLNARKLGDDVPPYVYAT 698

Query: 57  PLEKDGITV--VDWPFD--DGAPPPGKVVEDWLSL 87
             E   + +  +DWP     G    G+ ++  + L
Sbjct: 699 EDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGL 733


>4KI9-A nrPDB
          Length = 163

 Score = 29.7 bits (65), Expect = 0.68,   Method: Composition-based stats.
 Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 6/85 (7%)

Query: 73  GAPPPGKVVEDWLSLVKAKFCE-----APGSCVAVHCVAGLGRAPVLVALALIES-GMKY 126
             P   K   D LS +           A G  V VH  AG+ R+  ++   L+++  + +
Sbjct: 53  FVPALDKPETDLLSHLDRAVAFIGQARAEGRAVLVHSHAGVSRSVAIITAFLMKTDQLPF 112

Query: 127 EDAIQFIRQKRRGAINSKQLTYLEK 151
           E A + ++  +  A  ++   +  K
Sbjct: 113 EKAYEKLQILKPEAKMNEGFEWQLK 137


>5MIO-C nrPDB
          Length = 573

 Score = 28.9 bits (63), Expect = 1.3,   Method: Composition-based stats.
 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 6/73 (8%)

Query: 1  MARMNRPAPVEVSYKHMRFLITHNPTNATLS----TFIEDLKKYGATTVVRVCEVTYDKT 56
          M RM R    + S+ +  F        ATL     T  + ++++     VR  +   +K 
Sbjct: 1  MGRMKRAQEYDSSFPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVR--KRPLNKQ 58

Query: 57 PLEKDGITVVDWP 69
           L K  I V+  P
Sbjct: 59 ELAKKEIDVISIP 71


>2REO-A nrPDB
          Length = 305

 Score = 28.1 bits (61), Expect = 1.7,   Method: Composition-based stats.
 Identities = 18/100 (18%), Positives = 32/100 (32%), Gaps = 8/100 (8%)

Query: 7   PAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYD--KTPLEKDGIT 64
           P    VSY H   + +  P    L  F E            V    +D  K       + 
Sbjct: 142 PKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKV-----VGGSWFDHVKGWWAAKDMH 196

Query: 65  -VVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVH 103
            ++   ++D    P + +E  L  ++    E   + +  H
Sbjct: 197 RILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYH 236


>3R2N-A nrPDB
          Length = 138

 Score = 28.1 bits (61), Expect = 2.2,   Method: Composition-based stats.
 Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 7/76 (9%)

Query: 85  LSLVKAKFCEAPGSCVAVHCVAGLGRA--PVLVALALIESGMKYEDAIQFIRQKRRGAIN 142
            S++ A +    G  VAV+CV G G +  P           + YE     ++      + 
Sbjct: 63  CSMISALYATGGGRLVAVYCVDGNGDSLMPCGRC-----RQLLYEHGGPELKIMTPKGVQ 117

Query: 143 SKQLTYLEKYRPKQRL 158
           +      + + P++R+
Sbjct: 118 TMAQLLPQAFNPQERI 133


>1KF9-A nrPDB
          Length = 191

 Score = 27.8 bits (60), Expect = 2.7,   Method: Composition-based stats.
 Identities = 9/44 (20%), Positives = 17/44 (38%)

Query: 53  YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP 96
           YD     ++GI  +    +DG+P  G++ +   S          
Sbjct: 111 YDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDD 154


>4PYH-A nrPDB
          Length = 294

 Score = 27.4 bits (59), Expect = 3.5,   Method: Composition-based stats.
 Identities = 17/76 (22%), Positives = 28/76 (36%), Gaps = 1/76 (1%)

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-E 121
           I  +     D      ++    +     K  +  G    VH  AG+GRAP +    +   
Sbjct: 72  IQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWV 131

Query: 122 SGMKYEDAIQFIRQKR 137
            G K  +A + +  KR
Sbjct: 132 QGYKLMEAHKLLMSKR 147


>5A94-A nrPDB
          Length = 365

 Score = 27.4 bits (59), Expect = 3.6,   Method: Composition-based stats.
 Identities = 12/46 (26%), Positives = 20/46 (43%)

Query: 52  TYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97
              K P+E++GI     P+   A P  K  +++  L   K+  A  
Sbjct: 238 PIKKAPIEREGIAYAAHPYPQKAKPEVKNDKNFFKLWDEKWGFAAD 283


>6OIX-A nrPDB
          Length = 505

 Score = 27.0 bits (58), Expect = 3.9,   Method: Composition-based stats.
 Identities = 14/68 (20%), Positives = 26/68 (38%)

Query: 4   MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63
           +N PA   +  K   F +  N    T  T   ++++ G      +     +   LE  G+
Sbjct: 40  INSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGL 99

Query: 64  TVVDWPFD 71
             +  PF+
Sbjct: 100 DELTGPFE 107


>1OBQ-A nrPDB
          Length = 181

 Score = 26.6 bits (57), Expect = 5.1,   Method: Composition-based stats.
 Identities = 10/46 (21%), Positives = 19/46 (41%)

Query: 17 MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDG 62
           +F +T+NP          +    G   V+    + YD   L+++G
Sbjct: 36 YQFALTNNPYQLIEKCVRNEYSFDGKQFVIESTGIAYDGNLLKRNG 81


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.311    0.130    0.348 

Lambda     K      H
   0.267   0.0402    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,412,289
Number of Sequences: 36641
Number of extensions: 222014
Number of successful extensions: 1003
Number of sequences better than 10.0: 125
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 806
Number of HSP's gapped (non-prelim): 215
length of query: 173
length of database: 10,336,785
effective HSP length: 90
effective length of query: 83
effective length of database: 7,039,095
effective search space: 584244885
effective search space used: 584244885
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 55 (25.8 bits)