BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O75365 (173 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1V3A-A nrPDB 362 e-101 5LXQ-B nrPDB 298 1e-81 1XM2-A nrPDB 294 2e-80 3RZ2-A nrPDB 289 3e-79 5K23-A nrPDB 283 3e-77 5K22-A nrPDB 281 1e-76 1ZCK-A nrPDB 268 7e-73 3S4O-A nrPDB 131 1e-31 1OHC-A nrPDB 62 9e-11 5XW4-A nrPDB 54 4e-08 5Z59-A nrPDB 48 3e-06 3RO1-A nrPDB 45 2e-05 4BPC-A nrPDB 44 3e-05 5BZX-A nrPDB 43 6e-05 1LAR-A nrPDB 43 7e-05 4ERC-A nrPDB 42 2e-04 3M4U-A nrPDB 41 3e-04 4AZ1-A nrPDB 38 0.002 6D3F-A nrPDB 38 0.003 2JJD-A nrPDB 37 0.003 5HDE-A nrPDB 37 0.004 4YR8-G nrPDB 37 0.006 1YN9-A nrPDB 36 0.007 2C46-A nrPDB 36 0.007 2R0B-A nrPDB 36 0.008 2H03-A nrPDB 36 0.010 2I75-A nrPDB 34 0.027 1P15-A nrPDB 34 0.034 1I9T-A nrPDB 34 0.035 2B3O-A nrPDB 33 0.049 1WRM-A nrPDB 33 0.063 2PI7-A nrPDB 33 0.066 3I36-A nrPDB 33 0.086 4GE6-A nrPDB 32 0.100 1WCH-A nrPDB 32 0.11 2RF6-A nrPDB 32 0.12 4BJO-A nrPDB 32 0.16 2Y96-A nrPDB 32 0.18 2GJT-A nrPDB 32 0.19 6DR7-A nrPDB 32 0.21 4OTK-A nrPDB 32 0.21 3RGQ-A nrPDB 31 0.21 2CFV-A nrPDB 31 0.22 1ZZW-A nrPDB 31 0.24 6H8S-A nrPDB 31 0.24 2OUD-A nrPDB 31 0.25 4JMK-A nrPDB 31 0.29 3V0J-A nrPDB 31 0.29 3PS5-A nrPDB 30 0.45 5OVR-A nrPDB 30 0.48 4HJQ-A nrPDB 30 0.49 2G6Z-A nrPDB 30 0.55 3S3F-A nrPDB 30 0.60 4PVG-A nrPDB 30 0.79 6CMQ-A nrPDB 29 0.86 4H1O-A nrPDB 29 0.86 2QEP-A nrPDB 29 0.92 3EZZ-A nrPDB 29 1.3 1RPM-A nrPDB 28 1.6 3F41-A nrPDB 28 1.7 5XJV-A nrPDB 28 1.9 6D67-A nrPDB 28 2.0 2A8B-A nrPDB 28 2.0 1M3G-A nrPDB 28 2.4 4IKC-A nrPDB 28 2.6 4KYQ-A nrPDB 27 3.1 2QLU-A nrPDB 27 3.1 2BZL-A nrPDB 27 3.1 2NV5-A nrPDB 27 3.2 1YFO-A nrPDB 27 3.3 2Q4E-A nrPDB 27 3.5 1ZC0-A nrPDB 27 4.4 3RFW-A nrPDB 27 4.9 6HS3-A nrPDB 27 5.5 3LJ8-A nrPDB 26 6.8 1UPI-A nrPDB 26 7.3 1PM7-A nrPDB 26 7.8 1Z2E-A nrPDB 26 7.9 >1V3A-A nrPDB Length = 173 Score = 362 bits (930), Expect = e-101, Method: Compositional matrix adjust. Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK Sbjct: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI Sbjct: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173 >5LXQ-B nrPDB Length = 196 Score = 298 bits (762), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 136/172 (79%), Positives = 152/172 (88%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 24 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 83 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI Sbjct: 84 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 143 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+ Sbjct: 144 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 195 >1XM2-A nrPDB Length = 173 Score = 294 bits (752), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 135/172 (78%), Positives = 151/172 (87%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVH VAGLGRAPVLVALALI Sbjct: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALI 120 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+ Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172 >3RZ2-A nrPDB Length = 189 Score = 289 bits (740), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 134/168 (79%), Positives = 149/168 (88%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 21 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 80 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI Sbjct: 81 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 140 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKT 168 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ Sbjct: 141 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRN 188 >5K23-A nrPDB Length = 189 Score = 283 bits (724), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 131/169 (77%), Positives = 149/169 (88%), Gaps = 3/169 (1%) Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63 MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+GI Sbjct: 23 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 82 Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123 V+DWPFDDGAPPP ++V+DWL+L+K KF E PG CVAVHCVAGLGRAPVLVALALIE G Sbjct: 83 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 142 Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 MKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H CCV Sbjct: 143 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCV 188 >5K22-A nrPDB Length = 183 Score = 281 bits (718), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 127/165 (76%), Positives = 148/165 (89%) Query: 2 ARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKD 61 + MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+ Sbjct: 19 SHMNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKE 78 Query: 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121 GI V+DWPFDDGAPPP ++V+DWL+L+K KF E PG+ VAVHCVAGLGRAPVLVALALIE Sbjct: 79 GIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAAVAVHCVAGLGRAPVLVALALIE 138 Query: 122 SGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTH 166 +GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H Sbjct: 139 AGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 183 >1ZCK-A nrPDB Length = 154 Score = 268 bits (686), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 125/154 (81%), Positives = 138/154 (89%) Query: 7 PAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVV 66 PAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK+GI V+ Sbjct: 1 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 60 Query: 67 DWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126 DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALIE GMKY Sbjct: 61 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 120 Query: 127 EDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRF 160 EDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF Sbjct: 121 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 154 >3S4O-A nrPDB Length = 167 Score = 131 bits (330), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 67/144 (46%), Positives = 90/144 (62%), Gaps = 7/144 (4%) Query: 17 MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPP 76 FLI P+ + L T+I++L+ G +VRVC TYD T ++ GI V WPFDDGAPP Sbjct: 23 FHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSWPFDDGAPP 82 Query: 77 PGKVVEDWLSLVKAKFC------EAPGSCVAVHCVAGLGRAPVLVALALIESG-MKYEDA 129 V++ WL L+ + P + VHCVAGLGRAP+LVALAL+E G + DA Sbjct: 83 TRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEYGNVSALDA 142 Query: 130 IQFIRQKRRGAINSKQLTYLEKYR 153 I IR+KR+GAIN Q+ ++ KY+ Sbjct: 143 IALIREKRKGAINQTQMHWITKYK 166 >1OHC-A nrPDB Length = 348 Score = 62.4 bits (150), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 6/119 (5%) Query: 32 TFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91 T+I+ K + TT++R+ + YD G D F DG+ P +V+++L + Sbjct: 209 TYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI---- 264 Query: 92 FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149 CE +AVHC AGLGR L+A +++ M + I ++R R G++ Q +L Sbjct: 265 -CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 322 >5XW4-A nrPDB Length = 415 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 7/128 (5%) Query: 23 HNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVE 82 + P + L+ F + VVR+ Y+K E GI +D F+DG P +V+ Sbjct: 249 NQPFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVK 304 Query: 83 DWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAI 141 +++ A+ G +AVHC AGLGR L+ LI + G + I F+R R G + Sbjct: 305 NFVG--AAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMV 362 Query: 142 NSKQLTYL 149 Q +L Sbjct: 363 VGPQQHWL 370 >5Z59-A nrPDB Length = 147 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 5/129 (3%) Query: 18 RFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPP 77 R + P L D +V E+ Y EK G+ V+ P D P Sbjct: 11 RVAFSRMPAERELDEVARDFD--AVVVLVEDYELPYSLDEWEKRGVEVLHGPIPDFTAPS 68 Query: 78 GKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRA-PVLVALALIESGMKYEDAIQFIRQK 136 + + + L ++ + E G V +HC+ GLGR+ V VA + G+ +A+ +R+K Sbjct: 69 VEQLLEILRWIEERVRE--GKKVLIHCMGGLGRSGTVGVAWLMYSRGLSLREALMEVRRK 126 Query: 137 RRGAINSKQ 145 R GA+ +++ Sbjct: 127 RPGAVETQE 135 >3RO1-A nrPDB Length = 161 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 7/116 (6%) Query: 53 YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP 112 Y + L+K+G+ + P DG P +L+++K E G+ V HCV G+GR Sbjct: 50 YYLSILKKNGLQPLHIPIPDGGVPSDS---QFLTIMKWLLSEKEGNLV--HCVGGIGRTG 104 Query: 113 VLVALALI-ESGMKYEDAIQFIRQKRRGAINS-KQLTYLEKYRPKQRLRFKDPHTH 166 ++A LI G++ E AI +R R GA+ + +Q +L + ++ K+ +++ Sbjct: 105 TILASYLILTEGLEVESAIDEVRLVRPGAVQTYEQEMFLLRVEGMRKSWLKNIYSN 160 >4BPC-A nrPDB Length = 582 Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%) Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125 DWP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+ Sbjct: 477 DWP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMR 535 Query: 126 YEDAIQFIR 134 YE + + Sbjct: 536 YEGVVDIFQ 544 >5BZX-A nrPDB Length = 314 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 8/105 (7%) Query: 65 VVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG- 123 V +PF+D PP ++++ + + E A+HC AG GR V++ L+ G Sbjct: 72 VAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGK 131 Query: 124 -MKYEDAIQF---IRQKRRGAI---NSKQLTYLEKYRPKQRLRFK 161 +K ++A+ F +R + + + + ++ Y Y K L ++ Sbjct: 132 FLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYR 176 >1LAR-A nrPDB Length = 575 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Query: 67 DWPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMK 125 DWP + G P G+ D++ V K K + VHC AG+GR V + L+++ M+ Sbjct: 470 DWP-EQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR 528 Query: 126 YEDAIQFIR 134 YE + + Sbjct: 529 YEGVVDMFQ 537 Score = 29.3 bits (64), Expect = 1.0, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP D G P + +L VKA G V VHC AG+GR + + + MK+E Sbjct: 182 WP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVIDAMLERMKHE 239 Query: 128 DAI 130 + Sbjct: 240 KTV 242 >4ERC-A nrPDB Length = 150 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%) Query: 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI- 120 G+T+ D PP ++ ++ +V A G V VHC G GR ++A L+ Sbjct: 55 GLTLHRLRIPDFCPPAPDQIDRFVQIVDE--ANARGEAVGVHCALGFGRTGTMLACYLVK 112 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQ 145 E G+ DAI IR+ R G+I + + Sbjct: 113 ERGLAAGDAIAEIRRLRPGSIETYE 137 >3M4U-A nrPDB Length = 306 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 17/98 (17%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118 + V WP D G P ++ LS++K +P + VHC AG+GR L+ AL Sbjct: 192 VQYVGWP-DHGVPESAASFDELLSVIKNCVTTSP---ILVHCSAGIGRTGTLIGAYAALL 247 Query: 119 LIESGMKYEDAIQFI----RQKRRGAINSKQLTYLEKY 152 IE G+ + + I +QKR G + LE+Y Sbjct: 248 HIERGILTDSTVYSIVAAMKQKRFGMVQR-----LEQY 280 >4AZ1-A nrPDB Length = 302 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 12/97 (12%) Query: 54 DKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPV 113 D+ P + + WP D G P +E L+ VK P V VHC AG+GR Sbjct: 180 DEPPHKFTQVQYTGWP-DHGIPQSATSLEALLTNVKNSPTTVP---VVVHCSAGIGRTGT 235 Query: 114 LV----ALALIESGMKYE----DAIQFIRQKRRGAIN 142 L+ AL +E G + D + +R++R G + Sbjct: 236 LIGAYAALTHLERGTLTDTTVYDVVSAMRRQRFGMVQ 272 >6D3F-A nrPDB Length = 279 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP + G P GK + D ++ V+ + + + VHC AG GR +AL+ I +K E Sbjct: 174 WP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAE 232 Query: 128 ---DAIQFIRQKR 137 D Q ++ R Sbjct: 233 GLLDVFQAVKSLR 245 >2JJD-A nrPDB Length = 599 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP + G P GK + D ++ V+ + + + VHC AG GR +AL+ I +K E Sbjct: 490 WP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAE 548 Query: 128 ---DAIQFIRQKR 137 D Q ++ R Sbjct: 549 GLLDVFQAVKSLR 561 >5HDE-A nrPDB Length = 307 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 11/89 (12%) Query: 66 VDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL----ALIE 121 V+WP D P + D +SL++ K+ E + +HC AG GR + A+ L++ Sbjct: 201 VNWP-DHDVPSSFDSILDMISLMR-KYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLK 258 Query: 122 SGMKYE-----DAIQFIRQKRRGAINSKQ 145 +G E + IQ +R +R A+ +K+ Sbjct: 259 AGKIPEEFNVFNLIQEMRTQRHSAVQTKE 287 >4YR8-G nrPDB Length = 167 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 1/45 (2%) Query: 94 EAPGSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137 +A CV VHC+AG+ R A + +A + M ++A +F+++KR Sbjct: 100 KASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKR 144 >1YN9-A nrPDB Length = 169 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Query: 76 PPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIR 134 PP +V++++ VK + PG V VHC G+ R +V L+ + G+ ++AI Sbjct: 92 PPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTGYMVCRYLMHTLGIAPQEAIDRFE 151 Query: 135 QKRRGAINSKQ 145 + R I + Sbjct: 152 KARGHKIERQN 162 >2C46-A nrPDB Length = 241 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 28 ATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDD-GAPPPGKVVEDWL 85 + LS +++ LK K G + YD+ +EK+GI + G P + E ++ Sbjct: 70 SMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFI 129 Query: 86 SLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121 L + P + VHC G R L+ L+E Sbjct: 130 RLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVE 165 >2R0B-A nrPDB Length = 154 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 13/125 (10%) Query: 25 PTNATLSTFIEDLKKYGATTVVRV---CEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81 P ++ + + + L+K+G T ++ + E + K ++ + + D A P + + Sbjct: 17 PYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQ----LFRYLVLDIADNPVENI 72 Query: 82 EDWLSLVKAKFCEAP---GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137 + + K +F + G V VH AG+ R+ V ++E+ GMKY DA ++ Q+R Sbjct: 73 IRFFPMTK-EFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV-QER 130 Query: 138 RGAIN 142 R IN Sbjct: 131 RFCIN 135 >2H03-A nrPDB Length = 291 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 2/64 (3%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKY 126 WP D G P + + ++ V+ +PG+ VHC AG+GR +AL I + Sbjct: 189 WP-DHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDS 247 Query: 127 EDAI 130 +D++ Sbjct: 248 KDSV 251 >2I75-A nrPDB Length = 320 Score = 34.3 bits (77), Expect = 0.027, Method: Compositional matrix adjust. Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFC--EAPGSCVAVHCVAGLGRAPVLV----A 116 I + WP D G P D++ V+ K E P V VHC AG+GR VL+ A Sbjct: 205 IQYIAWP-DHGVPDDSSDFLDFVCHVRNKRAGKEEP---VVVHCSAGIGRTGVLITMETA 260 Query: 117 LALIESGMKYE--DAIQFIRQKRRGAINS 143 + LIE D ++ +R +R I + Sbjct: 261 MCLIECNQPVYPLDIVRTMRDQRAMMIQT 289 >1P15-A nrPDB Length = 253 Score = 33.9 bits (76), Expect = 0.034, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP + G P GK + + ++ V+ + ++ + VHC AG GR AL+ + +K E Sbjct: 148 WP-EVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAE 206 Query: 128 ---DAIQFIRQKR 137 D Q ++ R Sbjct: 207 GILDVFQTVKSLR 219 >1I9T-A nrPDB Length = 210 Score = 33.9 bits (76), Expect = 0.035, Method: Compositional matrix adjust. Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 28 ATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDD-GAPPPGKVVEDWL 85 + LS +++ LK K + YD+ +EK+GI + G P + E ++ Sbjct: 48 SMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFI 107 Query: 86 SLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121 L + +P + VHC G R L+ L+E Sbjct: 108 RLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVE 143 >2B3O-A nrPDB Length = 532 Score = 33.5 bits (75), Expect = 0.049, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 13/90 (14%) Query: 66 VDWPFDDGAPP-PGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALAL---- 119 + WP D G P PG V+ +L + + P + + VHC AG+GR ++ + + Sbjct: 415 LSWP-DHGVPSEPGGVL-SFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMEN 472 Query: 120 -----IESGMKYEDAIQFIRQKRRGAINSK 144 ++ + + IQ +R +R G + ++ Sbjct: 473 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTE 502 >1WRM-A nrPDB Length = 165 Score = 33.1 bits (74), Expect = 0.063, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Query: 93 CEAPGSCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAIQFIRQKRRGAINS----KQLT 147 C G VHC+AG+ R+ LV A + + +EDA+ +R R A + +QL Sbjct: 79 CRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQ 138 Query: 148 YLEKYRPKQ 156 EK+ Q Sbjct: 139 EFEKHEVHQ 147 >2PI7-A nrPDB Length = 312 Score = 33.1 bits (74), Expect = 0.066, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 16/99 (16%) Query: 33 FIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD------------WPFDDGAPPPG-- 78 F ED YG TV + E + I+ D WP D G P Sbjct: 149 FTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWP-DHGVPTANAA 207 Query: 79 KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL 117 + + ++ +V+ K ++ G + +HC AG+GR +AL Sbjct: 208 ESILQFVQMVRQKSVKSKGPMI-IHCSAGVGRTGTFIAL 245 >3I36-A nrPDB Length = 342 Score = 32.7 bits (73), Expect = 0.086, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIESGMKY 126 WP D G P ++ ++ LV+ + P S + VHC AG+GR +A+ + ++ Sbjct: 208 WP-DHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIEN 266 Query: 127 EDAI 130 E+ + Sbjct: 267 ENTV 270 >4GE6-A nrPDB Length = 314 Score = 32.3 bits (72), Expect = 0.100, Method: Compositional matrix adjust. Identities = 23/98 (23%), Positives = 41/98 (41%), Gaps = 15/98 (15%) Query: 34 IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK-- 91 +E++ Y TT+ T ++ + + WP D G P + D+L +V+ + Sbjct: 161 VENMNHYKKTTLE--IHNTEERQKRQVTHFQFLSWP-DYGVPSSAASLIDFLRVVRNQQS 217 Query: 92 ------FCEAPGSC----VAVHCVAGLGRAPVLVALAL 119 + G C + VHC AG+GR +L + Sbjct: 218 LAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDI 255 >1WCH-A nrPDB Length = 315 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 10/83 (12%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVL----VALALIESG 123 WP D P +D L+ + + HC AG+GR+ L V L LI Sbjct: 214 WPDHDTPSQP----DDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQD 269 Query: 124 MKYE--DAIQFIRQKRRGAINSK 144 + ++ D ++ +R +R G + ++ Sbjct: 270 LDFDISDLVRCMRLQRHGMVQTE 292 >2RF6-A nrPDB Length = 176 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/77 (24%), Positives = 31/77 (40%), Gaps = 3/77 (3%) Query: 48 VCEVTYDKTPLEKDGITVVDWPF-DDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVA 106 V +T DK L I ++ P DD K +D + + C+ V VH A Sbjct: 60 VLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSK--CDQRNEPVLVHSAA 117 Query: 107 GLGRAPVLVALALIESG 123 G+ R+ ++ L+ Sbjct: 118 GVNRSGAMILAYLMSKN 134 >4BJO-A nrPDB Length = 338 Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust. Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 26 TNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWL 85 TN L+ ED+K Y + + +T +T E WP D G P ++L Sbjct: 155 TNLKLTLISEDIKSYYTVRQLELENLTTQETR-EILHFHYTTWP-DFGVPESPASFLNFL 212 Query: 86 SLVKAKFCEAPGSC-VAVHCVAGLGRA 111 V+ +P V VHC AG+GR+ Sbjct: 213 FKVRESGSLSPEHGPVVVHCSAGIGRS 239 >2Y96-A nrPDB Length = 219 Score = 31.6 bits (70), Expect = 0.18, Method: Compositional matrix adjust. Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 8/60 (13%) Query: 98 SCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAIQFIRQKR-----RGAINSKQLTYLEK 151 S + VHCV G R+ LV A +I M DAIQ + + R RG + KQL L+K Sbjct: 140 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFL--KQLRELDK 197 >2GJT-A nrPDB Length = 295 Score = 31.6 bits (70), Expect = 0.19, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 16/99 (16%) Query: 33 FIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD------------WPFDDGAPPPG-- 78 F E+ YG TV + E D I D WP D G P Sbjct: 140 FTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWP-DHGVPTANAA 198 Query: 79 KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL 117 + + ++ +V+ + ++ G + +HC AG+GR +AL Sbjct: 199 ESILQFVHMVRQQATKSKGPMI-IHCSAGVGRTGTFIAL 236 >6DR7-A nrPDB Length = 306 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 23/115 (20%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLV------KAKFCEAPGSCVA---------VHCVAG 107 + V WP D P +V + SLV K E+ GS +HC AG Sbjct: 187 VHVTTWP--DFGVPESEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAG 244 Query: 108 LGRAPVLVALALI----ESGMKYEDAIQFIRQKRRGAINSK--QLTYLEKYRPKQ 156 +GR L+ + S + ED + +R +R G + K QL L K Q Sbjct: 245 VGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQ 299 >4OTK-A nrPDB Length = 318 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 41 GATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91 G T C + D+ L+ + ++ WP APP GK V+ W +++++ Sbjct: 125 GFTRSQEACRASLDRLGLDYVDLYLIHWP----APPVGKYVDAWGGMIQSR 171 >3RGQ-A nrPDB Length = 156 Score = 31.2 bits (69), Expect = 0.21, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Query: 94 EAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRRG-AINSKQLTYLEK 151 +A G CV VH AG R+ +VA LI+ E+AI+ I + R +I QL L++ Sbjct: 87 QALGQCVYVHSKAGRSRSATMVAAYLIQVHNWSPEEAIEAIAKIRSHISIRPSQLEVLKE 146 Query: 152 Y 152 + Sbjct: 147 F 147 >2CFV-A nrPDB Length = 316 Score = 31.2 bits (69), Expect = 0.22, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 32/61 (52%), Gaps = 1/61 (1%) Query: 71 DDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIESGMKYEDA 129 D G P ++ ++ LV+ ++P S + VHC AG+GR +A+ + ++ E+ Sbjct: 210 DHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT 269 Query: 130 I 130 + Sbjct: 270 V 270 >1ZZW-A nrPDB Length = 149 Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 97 GSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137 G + +HC AG+ R A +++A + + M DA +F++ KR Sbjct: 83 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 124 >6H8S-A nrPDB Length = 301 Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 13/86 (15%) Query: 68 WPFD---DGAPPPGKVVEDWLSLVKAKFCEAPG-SCVAVHCVAGLGRAPVLVALALIESG 123 WP D APP +V + + +A E P S + VHC AG+GR +A ++ Sbjct: 197 WPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQ 253 Query: 124 MKYEDAIQF------IRQKRRGAINS 143 ++ E + +RQ R G I + Sbjct: 254 LRREGVVDILKTTCQLRQDRGGMIQT 279 >2OUD-A nrPDB Length = 177 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 97 GSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137 G + +HC AG+ R A +++A + + M DA +F++ KR Sbjct: 87 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 128 >4JMK-A nrPDB Length = 152 Score = 30.8 bits (68), Expect = 0.29, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 26/43 (60%), Gaps = 2/43 (4%) Query: 97 GSC-VAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137 SC V VH +AG+ R A + +A + GM +DA +F++ +R Sbjct: 80 SSCQVIVHSLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRR 122 >3V0J-A nrPDB Length = 334 Score = 30.8 bits (68), Expect = 0.29, Method: Compositional matrix adjust. Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Query: 45 VVRVC-EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVH 103 + +C E YD+T + V+ DD P + ++ K P +A+H Sbjct: 69 IYNLCSERGYDETKFDNHVYRVM---IDDHNVPTLVDLLKFIDDAKVWMTSDPDHVIAIH 125 Query: 104 CVAGLGRAPVLVALALIESGMKYE---DAIQFIRQKR----RGAINSKQLTYL 149 G GR LV+ L+E G K++ +A+++ +R +G + Q+ Y+ Sbjct: 126 SKGGKGRTGTLVSSWLLEDG-KFDTAKEALEYFGSRRTDVFQGVETASQIRYV 177 >3PS5-A nrPDB Length = 595 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 13/90 (14%) Query: 66 VDWPFDDGAPP-PGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALAL---- 119 + WP D G P PG V+ +L + + P + + VH AG+GR ++ + + Sbjct: 415 LSWP-DHGVPSEPGGVL-SFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMEN 472 Query: 120 -----IESGMKYEDAIQFIRQKRRGAINSK 144 ++ + + IQ +R +R G + ++ Sbjct: 473 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTE 502 >5OVR-A nrPDB Length = 305 Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Query: 68 WPFD---DGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESG 123 WP D APP +V + + +A E P + VHC AG+GR +A ++ Sbjct: 201 WPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQ 257 Query: 124 MKYEDAIQF------IRQKRRGAINS 143 ++ E + +RQ R G I + Sbjct: 258 LRQEGVVDILKTTCQLRQDRGGMIQT 283 >4HJQ-A nrPDB Length = 308 Score = 30.0 bits (66), Expect = 0.49, Method: Compositional matrix adjust. Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 13/90 (14%) Query: 66 VDWPFDDGAPP-PGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALAL---- 119 + WP D G P PG V+ +L + + P + + VH AG+GR ++ + + Sbjct: 195 LSWP-DHGVPSEPGGVL-SFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMEN 252 Query: 120 -----IESGMKYEDAIQFIRQKRRGAINSK 144 ++ + + IQ +R +R G + ++ Sbjct: 253 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTE 282 >2G6Z-A nrPDB Length = 211 Score = 30.0 bits (66), Expect = 0.55, Method: Compositional matrix adjust. Identities = 30/137 (21%), Positives = 57/137 (41%), Gaps = 24/137 (17%) Query: 8 APVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVR------VCEVTYDKTPLEKD 61 PVE+ + FL + +A+ F+ +L V R + + Y P+E Sbjct: 5 GPVEI----LPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLHYKWIPVEDS 60 Query: 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121 + F + D++ V+ K G V VH AG+ R+P + L++ Sbjct: 61 HTADISSHFQEAI--------DFIDCVREK-----GGKVLVHSEAGISRSPTICMAYLMK 107 Query: 122 S-GMKYEDAIQFIRQKR 137 + + ++A +I+Q+R Sbjct: 108 TKQFRLKEAFDYIKQRR 124 >3S3F-A nrPDB Length = 307 Score = 30.0 bits (66), Expect = 0.60, Method: Compositional matrix adjust. Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 8/84 (9%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP D G P P + + ++ + + A + VHC AG+GR+ + L I + Sbjct: 208 WP-DFGVPNPPQTLVRFVRAFRDRI-GAEQRPIVVHCSAGVGRSGTFITLDRILQQINTS 265 Query: 128 DAIQF------IRQKRRGAINSKQ 145 D + +R++R + ++Q Sbjct: 266 DYVDIFGIVYAMRKERVWMVQTEQ 289 >4PVG-A nrPDB Length = 298 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 13/88 (14%) Query: 68 WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALAL------ 119 WP D G P PG V+ D+L V K V VHC AG+GR + + + Sbjct: 185 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 242 Query: 120 ---IESGMKYEDAIQFIRQKRRGAINSK 144 ++ + IQ +R +R G + ++ Sbjct: 243 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 270 >6CMQ-A nrPDB Length = 427 Score = 29.3 bits (64), Expect = 0.86, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 13/88 (14%) Query: 68 WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALAL------ 119 WP D G P PG V+ D+L V K V VHC AG+GR + + + Sbjct: 321 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 378 Query: 120 ---IESGMKYEDAIQFIRQKRRGAINSK 144 ++ + IQ +R +R G + ++ Sbjct: 379 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 406 >4H1O-A nrPDB Length = 560 Score = 29.3 bits (64), Expect = 0.86, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 13/88 (14%) Query: 68 WPFDDGAPP-PGKVVEDWLSLVKAKFCE-APGSCVAVHCVAGLGRAPVLVALAL------ 119 WP D G P PG V+ D+L V K V VHC AG+GR + + + Sbjct: 444 WP-DHGVPSDPGGVL-DFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 501 Query: 120 ---IESGMKYEDAIQFIRQKRRGAINSK 144 ++ + IQ +R +R G + ++ Sbjct: 502 EKGVDCDIDVPKTIQMVRSQRSGMVQTE 529 >2QEP-A nrPDB Length = 304 Score = 29.3 bits (64), Expect = 0.92, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 10/84 (11%) Query: 70 FDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALI----ESGM 124 +D G P + + D+ K C SC + VHC G GR+ V + ++ G Sbjct: 199 YDRGVPSSSRSLLDFRR--KVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGA 256 Query: 125 KYED---AIQFIRQKRRGAINSKQ 145 K D ++ +R +R G + +K+ Sbjct: 257 KEIDIAATLEHLRDQRPGMVQTKE 280 >3EZZ-A nrPDB Length = 144 Score = 28.9 bits (63), Expect = 1.3, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 5/61 (8%) Query: 81 VEDWLSLVKAKFCEAPGSC---VAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQK 136 + W + ++ +A C V VH AG+ R A + +A +++ ++ E+A +F++Q+ Sbjct: 63 ISSWF-MEAIEYIDAVKDCRGRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQR 121 Query: 137 R 137 R Sbjct: 122 R 122 >1RPM-A nrPDB Length = 278 Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 5/81 (6%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP D G P + ++ VK+K + G V VHC AG GR + + ++ + E Sbjct: 183 WP-DHGVPYHATGLLGFVRQVKSKSPPSAGPLV-VHCSAGAGRTGCFIVIDIMLDMAERE 240 Query: 128 ---DAIQFIRQKRRGAINSKQ 145 D +R+ R +N Q Sbjct: 241 GVVDIYNCVRELRSRRVNMVQ 261 >3F41-A nrPDB Length = 629 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 15/69 (21%) Query: 103 HCVAGLGRAPVLVALALIESGMK---YEDAIQFIRQKRRGAINSKQL----------TYL 149 HC AG+GR + + + I K ++D IQ RQK G ++ ++ Y+ Sbjct: 238 HCYAGMGRTTIFMVMHDILKNAKDVSFDDIIQ--RQKLIGIVDLSEIPDKKKNYGRKAYI 295 Query: 150 EKYRPKQRL 158 E+Y+ Q Sbjct: 296 ERYQFVQHF 304 >5XJV-A nrPDB Length = 185 Score = 28.1 bits (61), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 93 CEAPGSCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAIQFIRQKR 137 PG+ V VH V G+ R+ LV A ++ + A+ +RQ R Sbjct: 118 LNTPGAKVLVHSVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHR 163 >6D67-A nrPDB Length = 520 Score = 28.1 bits (61), Expect = 2.0, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 1/42 (2%) Query: 97 GSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKR 137 G V VH AG+ R A + +A + + +K ++A +F++Q+R Sbjct: 451 GGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRR 492 >2A8B-A nrPDB Length = 283 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 5/47 (10%) Query: 100 VAVHCVAGLGRAPVLVALALIESGMKYE---DAIQFIRQKR--RGAI 141 V VHC AG+GR +A ++ +K E DA+ + Q R RG + Sbjct: 212 VVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGM 258 >1M3G-A nrPDB Length = 145 Score = 27.7 bits (60), Expect = 2.4, Method: Compositional matrix adjust. Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 24/122 (19%) Query: 31 STFIEDLKKYGATTVVRVCE---------VTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81 S+ ++ L+ G T V+ V Y P+E + + + F + G + Sbjct: 19 SSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI---GFI- 74 Query: 82 EDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGA 140 DW+ + G V VH AG+ R+ + L++S ++ ++A F++Q RRG Sbjct: 75 -DWV--------KNSGGRVLVHSQAGISRSATICLAYLMQSRRVRLDEAFDFVKQ-RRGV 124 Query: 141 IN 142 I+ Sbjct: 125 IS 126 >4IKC-A nrPDB Length = 281 Score = 27.7 bits (60), Expect = 2.6, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 18/99 (18%) Query: 34 IEDLK--KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK 91 I DLK ++G VR C T WP + G P + ++ LV+A Sbjct: 165 IRDLKIERHGDCMTVRQCNFTA--------------WP-EHGVPENSAPLIHFVKLVRAS 209 Query: 92 FCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAI 130 + VH AG+GR V +AL + + D + Sbjct: 210 RAHDTTPMI-VHSSAGVGRTGVFIALDHLTQHINDHDFV 247 >4KYQ-A nrPDB Length = 208 Score = 27.3 bits (59), Expect = 3.1, Method: Compositional matrix adjust. Identities = 11/13 (84%), Positives = 11/13 (84%) Query: 100 VAVHCVAGLGRAP 112 V VHC AGLGRAP Sbjct: 115 VYVHCSAGLGRAP 127 >2QLU-A nrPDB Length = 314 Score = 27.3 bits (59), Expect = 3.1, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 123 GMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158 GMK+E+ +QFI ++RG+ +L + + K L Sbjct: 65 GMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSL 100 >2BZL-A nrPDB Length = 325 Score = 27.3 bits (59), Expect = 3.1, Method: Compositional matrix adjust. Identities = 29/131 (22%), Positives = 52/131 (39%), Gaps = 27/131 (20%) Query: 39 KYGATTVVRVCEVTYDKTPLEKDGI-----------TVVDWPFDDGAPPPGKVVEDWLSL 87 K+ TT R V Y T L+ + DWP D G P + +L Sbjct: 175 KFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWP-DHGCPEDVQGFLSYLEE 233 Query: 88 VKA------KFCEAPGSC---VAVHCVAGLGRAPVLVALALIESGMKYEDAIQ------F 132 +++ E + + VHC AG+GR VL+ L+ +++ + ++ Sbjct: 234 IQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRL 293 Query: 133 IRQKRRGAINS 143 +R++R I + Sbjct: 294 LREQRMFMIQT 304 >2NV5-A nrPDB Length = 299 Score = 27.3 bits (59), Expect = 3.2, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 4/64 (6%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSC-VAVHCVAGLGRAPVLVALALIESGMKY 126 WP D G P +L VK C P + + VHC AG+GR + + + +K+ Sbjct: 191 WP-DHGVPEHPTPFLAFLRRVKT--CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKH 247 Query: 127 EDAI 130 E + Sbjct: 248 EKTV 251 >1YFO-A nrPDB Length = 302 Score = 27.3 bits (59), Expect = 3.3, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Query: 68 WPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127 WP D G P + +L VKA + G+ V VHC AG+GR V + + M E Sbjct: 198 WP-DFGVPFTPIGMLKFLKKVKACNPQYAGAIV-VHCSAGVGRTGTFVVIDAMLDMMHSE 255 Query: 128 ---DAIQFIRQKR 137 D F+ + R Sbjct: 256 RKVDVYGFVSRIR 268 >2Q4E-A nrPDB Length = 362 Score = 27.3 bits (59), Expect = 3.5, Method: Compositional matrix adjust. Identities = 10/27 (37%), Positives = 15/27 (55%) Query: 23 HNPTNATLSTFIEDLKKYGATTVVRVC 49 HNP A L F+ D +++G V+ C Sbjct: 133 HNPRTALLKEFLSDSERFGQLKTVQSC 159 >1ZC0-A nrPDB Length = 309 Score = 26.9 bits (58), Expect = 4.4, Method: Compositional matrix adjust. Identities = 23/102 (22%), Positives = 38/102 (37%), Gaps = 1/102 (0%) Query: 15 KHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGA 74 K + + T T I+D+K+ TV R + Y + I WP Sbjct: 152 KCVHYWPTEEETYGPFQIRIQDMKECPEYTV-RQLTIQYQEERRSVKHILFSAWPDHQTP 210 Query: 75 PPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA 116 G ++ + ++ A + VHC AG+GR +A Sbjct: 211 ESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIA 252 >3RFW-A nrPDB Length = 252 Score = 26.9 bits (58), Expect = 4.9, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 20/29 (68%) Query: 120 IESGMKYEDAIQFIRQKRRGAINSKQLTY 148 IE+G+K+E+ + I QK + +NS ++ Y Sbjct: 223 IENGLKFEEFKKVINQKGQDLLNSAKVEY 251 >6HS3-A nrPDB Length = 260 Score = 26.6 bits (57), Expect = 5.5, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 16 HMRFLITHNPTNATLSTFIEDLKK-YGATTVVRVCEVTYD 54 HM L P T S + +LKK YG+ TVV+ +V+ D Sbjct: 2 HMNALPNRQPAGTTSSLVVRNLKKRYGSRTVVK--DVSLD 39 >3LJ8-A nrPDB Length = 146 Score = 26.2 bits (56), Expect = 6.8, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 100 VAVHCVAGLGRA-PVLVALALIESGMKYEDAIQFIRQKR 137 V VHC+AG+ R+ V VA + + + DA +++K+ Sbjct: 85 VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 123 >1UPI-A nrPDB Length = 225 Score = 26.2 bits (56), Expect = 7.3, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 4/38 (10%) Query: 43 TTVVRVCEVTYD----KTPLEKDGITVVDWPFDDGAPP 76 +TV+ +C Y+ T D VDWP DGA P Sbjct: 148 STVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAP 185 >1PM7-A nrPDB Length = 202 Score = 26.2 bits (56), Expect = 7.8, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 4/38 (10%) Query: 43 TTVVRVCEVTYD----KTPLEKDGITVVDWPFDDGAPP 76 +TV+ +C Y+ T D VDWP DGA P Sbjct: 128 STVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAP 165 >1Z2E-A nrPDB Length = 139 Score = 26.2 bits (56), Expect = 7.9, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 18/43 (41%) Query: 42 ATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84 A VV +C DK P+ + W FDD A G E W Sbjct: 75 ADLVVTLCGDAADKCPMTPPHVKREHWGFDDPARAQGTEEEKW 117 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5LXQ-B nrPDB 285 1e-77 1XM2-A nrPDB 278 6e-76 3RZ2-A nrPDB 274 1e-74 1V3A-A nrPDB 274 1e-74 5K23-A nrPDB 268 8e-73 5K22-A nrPDB 265 6e-72 1ZCK-A nrPDB 249 4e-67 3S4O-A nrPDB 172 9e-44 5XW4-A nrPDB 149 8e-37 5Z59-A nrPDB 146 6e-36 1OHC-A nrPDB 144 2e-35 3RO1-A nrPDB 125 9e-30 5BZX-A nrPDB 111 1e-25 4ERC-A nrPDB 101 1e-22 4BPC-A nrPDB 87 5e-18 1LAR-A nrPDB 85 1e-17 3M4U-A nrPDB 83 6e-17 Sequences not found previously or not previously below threshold: 4AZ1-A nrPDB 69 9e-13 6D3F-A nrPDB 69 9e-13 2JJD-A nrPDB 69 1e-12 1P15-A nrPDB 67 3e-12 3V0J-A nrPDB 66 8e-12 2B3O-A nrPDB 66 8e-12 2H03-A nrPDB 65 1e-11 2C46-A nrPDB 64 3e-11 1YN9-A nrPDB 64 5e-11 1FPZ-A nrPDB 62 2e-10 4HJQ-A nrPDB 61 2e-10 3PS5-A nrPDB 61 2e-10 1I9T-A nrPDB 61 3e-10 3I36-A nrPDB 60 5e-10 4GE6-A nrPDB 60 6e-10 2NV5-A nrPDB 58 2e-09 2BZL-A nrPDB 58 2e-09 2CFV-A nrPDB 57 4e-09 6D4D-A nrPDB 57 4e-09 5OVR-A nrPDB 57 4e-09 2A8B-A nrPDB 57 4e-09 4BJO-A nrPDB 57 5e-09 1L8K-A nrPDB 57 6e-09 4H1O-A nrPDB 56 8e-09 6CMQ-A nrPDB 56 8e-09 2I75-A nrPDB 56 9e-09 1RPM-A nrPDB 55 1e-08 5HDE-A nrPDB 55 1e-08 4PVG-A nrPDB 55 1e-08 2GJT-A nrPDB 55 2e-08 2QEP-A nrPDB 55 2e-08 2PI7-A nrPDB 55 2e-08 2I1Y-A nrPDB 55 2e-08 1ZC0-A nrPDB 54 3e-08 3OLR-A nrPDB 53 6e-08 6H8S-A nrPDB 53 6e-08 1WCH-A nrPDB 52 1e-07 3S3F-A nrPDB 52 1e-07 1YFO-A nrPDB 52 1e-07 2C7S-A nrPDB 52 2e-07 2OOQ-A nrPDB 51 3e-07 1WRM-A nrPDB 51 3e-07 4YR8-G nrPDB 50 6e-07 1YGU-A nrPDB 50 6e-07 2R0B-A nrPDB 49 8e-07 4RHG-A nrPDB 49 8e-07 4IKC-A nrPDB 49 1e-06 2Q47-A nrPDB 48 3e-06 4GFV-A nrPDB 47 4e-06 5AWX-A nrPDB 47 4e-06 4KYQ-A nrPDB 47 5e-06 3F41-A nrPDB 47 6e-06 2NLK-A nrPDB 46 9e-06 2PBN-A nrPDB 45 1e-05 3RGQ-A nrPDB 45 2e-05 3LJ8-A nrPDB 45 2e-05 2G6Z-A nrPDB 44 3e-05 6N8N-Y nrPDB 44 3e-05 4MBB-A nrPDB 44 3e-05 1M3G-A nrPDB 43 5e-05 4NX8-A nrPDB 43 6e-05 6DR7-A nrPDB 43 7e-05 4TVV-A nrPDB 42 1e-04 1ZZW-A nrPDB 42 1e-04 4B04-A nrPDB 42 1e-04 5GTJ-A nrPDB 42 1e-04 2OUD-A nrPDB 42 1e-04 1J4X-A nrPDB 41 2e-04 4JMK-A nrPDB 41 3e-04 1G4W-R nrPDB 41 3e-04 5M43-A nrPDB 41 3e-04 5XJV-A nrPDB 40 5e-04 2Y96-A nrPDB 40 5e-04 1YZ4-A nrPDB 40 6e-04 2RF6-A nrPDB 40 6e-04 6I28-A nrPDB 40 7e-04 6D67-A nrPDB 39 0.001 4Y2E-A nrPDB 39 0.001 2ESB-A nrPDB 39 0.001 3EZZ-A nrPDB 38 0.002 2M3V-A nrPDB 38 0.002 3D1Q-A nrPDB 37 0.003 2WGP-A nrPDB 37 0.003 1MKP-A nrPDB 37 0.005 4R0S-A nrPDB 37 0.006 4R30-A nrPDB 36 0.008 4RKK-A nrPDB 36 0.009 6E3B-A nrPDB 36 0.010 2HCM-A nrPDB 34 0.028 5Y15-A nrPDB 33 0.079 2OZ5-A nrPDB 32 0.10 5NCR-A nrPDB 32 0.12 4D3P-A nrPDB 32 0.15 2QFY-A nrPDB 32 0.15 4CBI-A nrPDB 31 0.32 5WSO-A nrPDB 30 0.43 5WX1-A nrPDB 30 0.65 4KI9-A nrPDB 30 0.68 5MIO-C nrPDB 29 1.3 2REO-A nrPDB 28 1.7 3R2N-A nrPDB 28 2.2 1KF9-A nrPDB 28 2.7 4PYH-A nrPDB 27 3.5 5A94-A nrPDB 27 3.6 6OIX-A nrPDB 27 3.9 1OBQ-A nrPDB 27 5.1 >5LXQ-B nrPDB Length = 196 Score = 285 bits (728), Expect = 1e-77, Method: Composition-based stats. Identities = 136/172 (79%), Positives = 152/172 (88%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 24 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 83 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI Sbjct: 84 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 143 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+ Sbjct: 144 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 195 >1XM2-A nrPDB Length = 173 Score = 278 bits (712), Expect = 6e-76, Method: Composition-based stats. Identities = 135/172 (78%), Positives = 151/172 (87%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVH VAGLGRAPVLVALALI Sbjct: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALI 120 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+ Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172 >3RZ2-A nrPDB Length = 189 Score = 274 bits (701), Expect = 1e-74, Method: Composition-based stats. Identities = 134/169 (79%), Positives = 149/169 (88%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 21 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 80 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI Sbjct: 81 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 140 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTR 169 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ Sbjct: 141 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN 189 >1V3A-A nrPDB Length = 173 Score = 274 bits (701), Expect = 1e-74, Method: Composition-based stats. Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK Sbjct: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI Sbjct: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173 >5K23-A nrPDB Length = 189 Score = 268 bits (685), Expect = 8e-73, Method: Composition-based stats. Identities = 131/169 (77%), Positives = 149/169 (88%), Gaps = 3/169 (1%) Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63 MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+GI Sbjct: 23 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 82 Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123 V+DWPFDDGAPPP ++V+DWL+L+K KF E PG CVAVHCVAGLGRAPVLVALALIE G Sbjct: 83 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 142 Query: 124 MKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 MKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H CCV Sbjct: 143 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCV 188 >5K22-A nrPDB Length = 183 Score = 265 bits (678), Expect = 6e-72, Method: Composition-based stats. Identities = 127/165 (76%), Positives = 148/165 (89%) Query: 2 ARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKD 61 + MNRPAPVE+SY++MRFLITHNPTNATL+ F E+LKKYG TT+VRVC+ TYDK P+EK+ Sbjct: 19 SHMNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKE 78 Query: 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE 121 GI V+DWPFDDGAPPP ++V+DWL+L+K KF E PG+ VAVHCVAGLGRAPVLVALALIE Sbjct: 79 GIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAAVAVHCVAGLGRAPVLVALALIE 138 Query: 122 SGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTH 166 +GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF+D + H Sbjct: 139 AGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 183 >1ZCK-A nrPDB Length = 154 Score = 249 bits (636), Expect = 4e-67, Method: Composition-based stats. Identities = 125/154 (81%), Positives = 138/154 (89%) Query: 7 PAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVV 66 PAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK+GI V+ Sbjct: 1 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 60 Query: 67 DWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126 DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALIE GMKY Sbjct: 61 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 120 Query: 127 EDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRF 160 EDA+QFIRQKRRGA NSKQL YLEKYRPK RLRF Sbjct: 121 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 154 >3S4O-A nrPDB Length = 167 Score = 172 bits (435), Expect = 9e-44, Method: Composition-based stats. Identities = 67/144 (46%), Positives = 90/144 (62%), Gaps = 7/144 (4%) Query: 17 MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPP 76 FLI P+ + L T+I++L+ G +VRVC TYD T ++ GI V WPFDDGAPP Sbjct: 23 FHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSWPFDDGAPP 82 Query: 77 PGKVVEDWLSLVKAKFC------EAPGSCVAVHCVAGLGRAPVLVALALIESG-MKYEDA 129 V++ WL L+ + P + VHCVAGLGRAP+LVALAL+E G + DA Sbjct: 83 TRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEYGNVSALDA 142 Query: 130 IQFIRQKRRGAINSKQLTYLEKYR 153 I IR+KR+GAIN Q+ ++ KY+ Sbjct: 143 IALIREKRKGAINQTQMHWITKYK 166 >5XW4-A nrPDB Length = 415 Score = 149 bits (375), Expect = 8e-37, Method: Composition-based stats. Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 7/139 (5%) Query: 22 THNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVV 81 + P + L+ F + VVR+ Y+K E GI +D F+DG P +V Sbjct: 248 LNQPFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIV 303 Query: 82 EDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRRGA 140 ++++ A+ G +AVHC AGLGR L+ LI G + I F+R R G Sbjct: 304 KNFVG--AAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGM 361 Query: 141 INSKQLTYLEKYRPKQRLR 159 + Q +L ++ R Sbjct: 362 VVGPQQHWLYLHQNDFREW 380 >5Z59-A nrPDB Length = 147 Score = 146 bits (367), Expect = 6e-36, Method: Composition-based stats. Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%) Query: 18 RFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPP 77 R + P L D +V E+ Y EK G+ V+ P D P Sbjct: 11 RVAFSRMPAERELDEVARDFD--AVVVLVEDYELPYSLDEWEKRGVEVLHGPIPDFTAPS 68 Query: 78 GKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP-VLVALALIESGMKYEDAIQFIRQK 136 + + + L ++ + E G V +HC+ GLGR+ V VA + G+ +A+ +R+K Sbjct: 69 VEQLLEILRWIEERVRE--GKKVLIHCMGGLGRSGTVGVAWLMYSRGLSLREALMEVRRK 126 Query: 137 RRGAINSKQLTYLEK 151 R GA+ +++ + K Sbjct: 127 RPGAVETQEQMEVLK 141 >1OHC-A nrPDB Length = 348 Score = 144 bits (363), Expect = 2e-35, Method: Composition-based stats. Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 8/135 (5%) Query: 31 STFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKA 90 T+I+ K + TT++R+ + YD G D F DG+ P +V+++L + Sbjct: 208 ETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDI--- 264 Query: 91 KFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINSKQLTYL 149 CE +AVHC AGLGR L+A ++ M + I ++R R G++ Q +L Sbjct: 265 --CENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 322 Query: 150 EKYRPKQRLRFKDPH 164 + L + + Sbjct: 323 --VMKQTNLWLEGDY 335 >3RO1-A nrPDB Length = 161 Score = 125 bits (314), Expect = 9e-30, Method: Composition-based stats. Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 7/116 (6%) Query: 53 YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP 112 Y + L+K+G+ + P DG P +L+++K E G+ VHCV G+GR Sbjct: 50 YYLSILKKNGLQPLHIPIPDGGVPSDSQ---FLTIMKWLLSEKEGN--LVHCVGGIGRTG 104 Query: 113 VLVALALI-ESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRLRFKDPHTH 166 ++A LI G++ E AI +R R GA+ + Q +L + ++ K+ +++ Sbjct: 105 TILASYLILTEGLEVESAIDEVRLVRPGAVQTYEQEMFLLRVEGMRKSWLKNIYSN 160 >5BZX-A nrPDB Length = 314 Score = 111 bits (278), Expect = 1e-25, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 12/135 (8%) Query: 36 DLKKYGATTVVRVC-EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCE 94 D K + +C E YD V +PF+D PP ++++ + + E Sbjct: 45 DSKHKNHYKIYNLCAERHYDTAKFNCR---VAQYPFEDHNPPQLELIKPFCEDLDQWLSE 101 Query: 95 APGSCVAVHCVAGLGRAPVLVALALIESG--MKYEDAIQF---IRQKRRGAI---NSKQL 146 A+HC AG GR V++ L+ G +K ++A+ F +R + + + + ++ Sbjct: 102 DDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRY 161 Query: 147 TYLEKYRPKQRLRFK 161 Y Y K L ++ Sbjct: 162 VYYYSYLLKNHLDYR 176 >4ERC-A nrPDB Length = 150 Score = 101 bits (252), Expect = 1e-22, Method: Composition-based stats. Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 8/120 (6%) Query: 30 LSTFIEDLKKYGATTVVRVCE--VTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSL 87 L + L G +V + E + + G+T+ D PP ++ ++ + Sbjct: 24 LPAHYQFLLDLGVRHLVSLTERGPPHSDSC---PGLTLHRLRIPDFCPPAPDQIDRFVQI 80 Query: 88 VKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINSKQL 146 V A G V VHC G GR ++A L+ E G+ DAI IR+ R G+I + + Sbjct: 81 VDE--ANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQ 138 >4BPC-A nrPDB Length = 582 Score = 86.7 bits (213), Expect = 5e-18, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 21/152 (13%) Query: 9 PVEVSYKHMRFLITHNPTNATLSTFI-EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD 67 P E S ++ F++ + +I + K A D D Sbjct: 429 PAERSARYQYFVVDPM-AEYNMPQYILREFKVTDAR----------DGQSRTVRQFQFTD 477 Query: 68 WPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126 WP + G P G+ D++ V K K ++VHC AG+GR V + L+++ M+Y Sbjct: 478 WP-EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRY 536 Query: 127 EDAIQFI------RQKRRGAINSK-QLTYLEK 151 E + R +R + ++ + + + Sbjct: 537 EGVVDIFQTVKMLRTQRPAMVQTEDEYQFAYQ 568 Score = 55.1 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 34/94 (36%), Gaps = 8/94 (8%) Query: 59 EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118 E WP D G P +L VK G + VHC AG+GR + + Sbjct: 180 EVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTANPPDAG-PIVVHCSAGVGRTGAFIVID 237 Query: 119 LIESGMKYEDAIQ------FIRQKRRGAINSKQL 146 + +K E + +R +R + ++ Sbjct: 238 AMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQ 271 >1LAR-A nrPDB Length = 575 Score = 85.2 bits (209), Expect = 1e-17, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 20/149 (13%) Query: 9 PVEVSYKHMRFLITHNPTNATLSTFI-EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD 67 P E S ++ F++ + +I + K A D D Sbjct: 422 PAERSARYQYFVVDPM-AEYNMPQYILREFKVTDAR----------DGQSRTIRQFQFTD 470 Query: 68 WPFDDGAPPPGKVVEDWLSLV-KAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKY 126 WP + G P G+ D++ V K K + VHC AG+GR V + L+++ M+Y Sbjct: 471 WP-EQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRY 529 Query: 127 EDAIQFI------RQKRRGAINSKQLTYL 149 E + R +R + ++ L Sbjct: 530 EGVVDMFQTVKTLRTQRPAMVQTEDQYQL 558 Score = 59.7 bits (143), Expect = 6e-10, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 9/100 (9%) Query: 59 EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118 E + WP D G P + +L VKA G V VHC AG+GR + + Sbjct: 173 ELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVID 230 Query: 119 LIESGMKYEDAIQF------IRQKRRGAINSK-QLTYLEK 151 + MK+E + +R +R + ++ Q ++ + Sbjct: 231 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE 270 >3M4U-A nrPDB Length = 306 Score = 82.8 bits (203), Expect = 6e-17, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 12/92 (13%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118 + V WP D G P ++ LS++K +P + VHC AG+GR L+ AL Sbjct: 192 VQYVGWP-DHGVPESAASFDELLSVIKNCVTTSP---ILVHCSAGIGRTGTLIGAYAALL 247 Query: 119 LIESGMKYEDAIQFI----RQKRRGAINSKQL 146 IE G+ + + I +QKR G + + Sbjct: 248 HIERGILTDSTVYSIVAAMKQKRFGMVQRLEQ 279 >4AZ1-A nrPDB Length = 302 Score = 69.4 bits (168), Expect = 9e-13, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 12/104 (11%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA---- 118 + WP D G P +E L+ VK P V VHC AG+GR L+ Sbjct: 189 VQYTGWP-DHGIPQSATSLEALLTNVKNSPTTVP---VVVHCSAGIGRTGTLIGAYAALT 244 Query: 119 LIESGMKYEDAIQFI----RQKRRGAINSKQLTYLEKYRPKQRL 158 +E G + + + R++R G + + ++ RL Sbjct: 245 HLERGTLTDTTVYDVVSAMRRQRFGMVQRMEQYFVIYLTLMCRL 288 >6D3F-A nrPDB Length = 279 Score = 69.0 bits (167), Expect = 9e-13, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 WP + G P GK + D ++ V+ + + + VHC AG GR +AL+ I Sbjct: 167 RQFHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNI 225 Query: 121 ESGMKYED------AIQFIRQKRRGAINS-KQLTYLEKY 152 +K E A++ +R +R + + +Q + K Sbjct: 226 LERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKV 264 >2JJD-A nrPDB Length = 599 Score = 69.0 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 WP + G P GK + D ++ V+ + + + VHC AG GR +AL+ I Sbjct: 483 RQFHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNI 541 Query: 121 ESGMKYED------AIQFIRQKRRGAINS-KQLTYLEKY 152 +K E A++ +R +R + + +Q + K Sbjct: 542 LERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKV 580 Score = 57.8 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV------A 116 + WP D G P + +L VK + VHC AG+GR + A Sbjct: 191 LHFTSWP-DFGVPFTPIGMLKFLKKVKT-LNPVHAGPIVVHCSAGVGRTGTFIVIDAMMA 248 Query: 117 LALIESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRL 158 + E + + + IR +R + + Q T++ + + L Sbjct: 249 MMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYL 291 >1P15-A nrPDB Length = 253 Score = 67.1 bits (162), Expect = 3e-12, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 50/125 (40%), Gaps = 10/125 (8%) Query: 35 EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCE 94 E+ + Y ++ + + WP + G P GK + + ++ V+ + + Sbjct: 117 EECESYTVRDLLVTNTRENKSRQIRQ--FHFHGWP-EVGIPSDGKGMINIIAAVQKQQQQ 173 Query: 95 APGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQ------FIRQKRRGAINS-KQLT 147 + + VHC AG GR AL+ + +K E + +R +R + + +Q Sbjct: 174 SGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYE 233 Query: 148 YLEKY 152 + K Sbjct: 234 FCYKV 238 >3V0J-A nrPDB Length = 334 Score = 65.9 bits (159), Expect = 8e-12, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 5/107 (4%) Query: 50 EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLG 109 E YD+T + V DD P + ++ K P +A+H G G Sbjct: 75 ERGYDETKFDN---HVYRVMIDDHNVPTLVDLLKFIDDAKVWMTSDPDHVIAIHSKGGKG 131 Query: 110 RAPVLVALALIESGM--KYEDAIQFIRQKRRGAINSKQLTYLEKYRP 154 R LV+ L+E G ++A+++ +R + +Y Sbjct: 132 RTGTLVSSWLLEDGKFDTAKEALEYFGSRRTDVFQGVETASQIRYVG 178 >2B3O-A nrPDB Length = 532 Score = 65.9 bits (159), Expect = 8e-12, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 41/98 (41%), Gaps = 12/98 (12%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIES 122 + WP D G P V +L + + P + VHC AG+GR ++ + ++ Sbjct: 413 QYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLME 471 Query: 123 GMKY---------EDAIQFIRQKRRGAINSK-QLTYLE 150 + + IQ +R +R G + ++ Q ++ Sbjct: 472 NISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509 >2H03-A nrPDB Length = 291 Score = 65.1 bits (157), Expect = 1e-11, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 52/141 (36%), Gaps = 19/141 (13%) Query: 20 LITHNPTNATLSTF-IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPG 78 LI + + L + I + K +C WP D G P Sbjct: 149 LILQMLSESVLPEWTIREFK---------ICGEEQLDAHRLIRHFHYTVWP-DHGVPETT 198 Query: 79 KVVEDWLSLVKAKFCEAPG-SCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQF----- 132 + + ++ V+ +PG VHC AG+GR +AL I + +D++ Sbjct: 199 QSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVH 258 Query: 133 -IRQKRRGAINSK-QLTYLEK 151 +R R + ++ Q YL + Sbjct: 259 DLRLHRVHMVQTECQYVYLHQ 279 >2C46-A nrPDB Length = 241 Score = 64.0 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 47/118 (39%), Gaps = 3/118 (2%) Query: 27 NATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFD-DGAPPPGKVVEDW 84 + LS +++ LK K G + YD+ +EK+GI + G P + E + Sbjct: 69 PSMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETF 128 Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAI 141 + L + P + VHC G R L+ L+E E A+ Q R I Sbjct: 129 IRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGI 186 >1YN9-A nrPDB Length = 169 Score = 63.6 bits (153), Expect = 5e-11, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 1/96 (1%) Query: 53 YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAP 112 YD + G+ PP +V++++ VK + PG V VHC G+ R Sbjct: 69 YDGVHFLRAGLLYKKIQVPGQTLPPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTG 128 Query: 113 VLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLT 147 +V L+ + G+ ++AI + R I + Sbjct: 129 YMVCRYLMHTLGIAPQEAIDRFEKARGHKIERQNYV 164 >1FPZ-A nrPDB Length = 212 Score = 61.7 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 34/153 (22%), Positives = 54/153 (35%), Gaps = 16/153 (10%) Query: 27 NATLSTFIEDLKKYGATTVVRVCEV--------TYDKTPLEKDGITVVDWPFDDGAPPPG 78 + E+LK G + C ++ GI P DG P Sbjct: 57 RRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDI 116 Query: 79 KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE--SGMKYEDAIQFIRQK 136 + + + +H GLGR+ ++ A L+ + E AI +R Sbjct: 117 ASCCEIMEELTTCLKNYR--KTLIHSYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDL 174 Query: 137 R-RGAINS-KQLTYLEKYRPKQ--RLRFKDPHT 165 R GAI + KQ YL ++R K L +D + Sbjct: 175 RGSGAIQTIKQYNYLHEFRDKLAAHLSSRDSQS 207 >4HJQ-A nrPDB Length = 308 Score = 61.3 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 12/98 (12%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIES 122 + WP D G P V +L + + P + VH AG+GR ++ + ++ Sbjct: 193 QYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLME 251 Query: 123 GMKY---------EDAIQFIRQKRRGAINSK-QLTYLE 150 + + IQ +R +R G + ++ Q ++ Sbjct: 252 NISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 289 >3PS5-A nrPDB Length = 595 Score = 61.3 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 12/98 (12%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP-GSCVAVHCVAGLGRAPVLVALALIES 122 + WP D G P V +L + + P + VH AG+GR ++ + ++ Sbjct: 413 QYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLME 471 Query: 123 GMKY---------EDAIQFIRQKRRGAINSK-QLTYLE 150 + + IQ +R +R G + ++ Q ++ Sbjct: 472 NISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509 >1I9T-A nrPDB Length = 210 Score = 60.5 bits (145), Expect = 3e-10, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 3/118 (2%) Query: 27 NATLSTFIEDLK-KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFD-DGAPPPGKVVEDW 84 + LS +++ LK K + YD+ +EK+GI + G P + E + Sbjct: 47 PSMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETF 106 Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAI 141 + L + +P + VHC G R L+ L+E E A+ Q R I Sbjct: 107 IRLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGI 164 >3I36-A nrPDB Length = 342 Score = 60.1 bits (144), Expect = 5e-10, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 42/99 (42%), Gaps = 9/99 (9%) Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRAPVLVALAL 119 WP D G P ++ ++ LV+ + P + VHC AG+GR +A+ Sbjct: 201 RQFHFTSWP-DHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDR 259 Query: 120 IESGMKYEDAIQF------IRQKRRGAINSK-QLTYLEK 151 + ++ E+ + +R R + ++ Q +L + Sbjct: 260 LIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQ 298 >4GE6-A nrPDB Length = 314 Score = 59.7 bits (143), Expect = 6e-10, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 27/137 (19%) Query: 34 IEDLKKYGATTVVRVCEVTYDKTPLEKDGITV---VDWPFDDGAPPPGKVVEDWLSLVKA 90 +E++ Y TT+ ++ +K +T + WP D G P + D+L +V+ Sbjct: 161 VENMNHYKKTTL-----EIHNTEERQKRQVTHFQFLSWP-DYGVPSSAASLIDFLRVVRN 214 Query: 91 KFCEA------------PGSCVAVHCVAGLGRAPVL----VALALIES--GMKYEDAIQF 132 + A P + VHC AG+GR + LA +E + + Sbjct: 215 QQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSR 274 Query: 133 IRQKRRGAINSKQLTYL 149 +R +R +I + + Y Sbjct: 275 MRTQRAFSIQTPEQYYF 291 >2NV5-A nrPDB Length = 299 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 35/94 (37%), Gaps = 8/94 (8%) Query: 59 EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118 E WP D G P +L VK G V VHC AG+GR + + Sbjct: 182 EVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNPPDAGPMV-VHCSAGVGRTGCFIVID 239 Query: 119 LIESGMKYEDAIQF------IRQKRRGAINSKQL 146 + +K+E + +R +R + ++ Sbjct: 240 AMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQ 273 >2BZL-A nrPDB Length = 325 Score = 57.8 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 46/107 (42%), Gaps = 17/107 (15%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKA---------KFCEAPGSCVAVHCVAGLGRAPV 113 + DWP D G P + +L +++ + + + VHC AG+GR V Sbjct: 210 LQYTDWP-DHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGV 268 Query: 114 LVALALIESGMKYEDAIQ------FIRQKRRGAINS-KQLTYLEKYR 153 L+ L+ +++ + ++ +R++R I + Q ++ + Sbjct: 269 LILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVL 315 >2CFV-A nrPDB Length = 316 Score = 57.0 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Query: 71 DDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRAPVLVALALIESGMKYEDA 129 D G P ++ ++ LV+ ++P + VHC AG+GR +A+ + ++ E+ Sbjct: 210 DHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT 269 Query: 130 IQF------IRQKRRGAINSK-QLTYLEK 151 + +R R + ++ Q +L + Sbjct: 270 VDVYGIVYDLRMHRPLMVQTEDQYVFLNQ 298 >6D4D-A nrPDB Length = 292 Score = 57.0 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV------A 116 + WP D G P + +L VK + VHC AG+GR + A Sbjct: 190 LHFTSWP-DFGVPFTPIGMLKFLKKVKT-LNPVHAGPIVVHCSAGVGRTGTFIVIDAMMA 247 Query: 117 LALIESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRL 158 + E + + + IR +R + + Q T++ + + L Sbjct: 248 MMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYL 290 >5OVR-A nrPDB Length = 305 Score = 57.0 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 17/108 (15%) Query: 59 EKDGITVV---DWP---FDDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRA 111 E+ G+ WP D APP +V + + +A E P + VHC AG+GR Sbjct: 189 EERGLKHYWFTSWPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCAPIIVHCSAGIGRT 245 Query: 112 PVLVALALIESGMKYEDAIQF------IRQKRRGAINS-KQLTYLEKY 152 +A ++ ++ E + +RQ R G I + +Q ++ Sbjct: 246 GCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV 293 >2A8B-A nrPDB Length = 283 Score = 57.0 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 42/121 (34%), Gaps = 14/121 (11%) Query: 34 IEDLKKYGATTVV-RVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKF 92 + + Y +V + T WP D P + + + V+ Sbjct: 150 VNECDNYTIRNLVLKQGSHTQHVKHY-----WYTSWP-DHKTPDSAQPLLQLMLDVEEDR 203 Query: 93 CEAPG-SCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQ------FIRQKRRGAINSKQ 145 + G V VHC AG+GR +A ++ +K E + +R R G + + + Sbjct: 204 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE 263 Query: 146 L 146 Sbjct: 264 Q 264 >4BJO-A nrPDB Length = 338 Score = 56.7 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 12/132 (9%) Query: 26 TNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWL 85 TN L+ ED+K Y + + +T +T E WP D G P ++L Sbjct: 155 TNLKLTLISEDIKSYYTVRQLELENLTTQETR-EILHFHYTTWP-DFGVPESPASFLNFL 212 Query: 86 SLVKAKFCEAPG-SCVAVHCVAGLGRAPVL----VALALIESG-----MKYEDAIQFIRQ 135 V+ +P V VHC AG+GR+ L L++ + + + +R+ Sbjct: 213 FKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRK 272 Query: 136 KRRGAINSKQLT 147 R G I + Sbjct: 273 FRMGLIQTADQL 284 >1L8K-A nrPDB Length = 314 Score = 56.7 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 9/120 (7%) Query: 35 EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCE 94 ED+K Y ++++ + +T WP D G P ++L V+ Sbjct: 148 EDVKSYYTVHLLQLENINSGETRTISH-FHYTTWP-DFGVPESPASFLNFLFKVRESGSL 205 Query: 95 APG-SCVAVHCVAGLGRAPVL----VALALIESG--MKYEDAIQFIRQKRRGAINSKQLT 147 P +HC AG+GR+ L L+E G + + + +R+ R G I + Sbjct: 206 NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQL 265 >4H1O-A nrPDB Length = 560 Score = 56.3 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHCVAGLGRAPVLVALAL--- 119 WP D G P V D+L V K V VHC AG+GR + + + Sbjct: 440 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 498 Query: 120 ------IESGMKYEDAIQFIRQKRRGAINSK-QLTYLE 150 ++ + IQ +R +R G + ++ Q ++ Sbjct: 499 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 536 >6CMQ-A nrPDB Length = 427 Score = 55.9 bits (133), Expect = 8e-09, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHCVAGLGRAPVLVALAL--- 119 WP D G P V D+L V K V VHC AG+GR + + + Sbjct: 317 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 375 Query: 120 ------IESGMKYEDAIQFIRQKRRGAINSK-QLTYLE 150 ++ + IQ +R +R G + ++ Q ++ Sbjct: 376 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 413 >2I75-A nrPDB Length = 320 Score = 55.9 bits (133), Expect = 9e-09, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 8/90 (8%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118 I + WP D G P D++ V+ K V VHC AG+GR VL+ A+ Sbjct: 205 IQYIAWP-DHGVPDDSSDFLDFVCHVRNK-RAGKEEPVVVHCSAGIGRTGVLITMETAMC 262 Query: 119 LIESG--MKYEDAIQFIRQKRRGAINSKQL 146 LIE + D ++ +R +R I + Sbjct: 263 LIECNQPVYPLDIVRTMRDQRAMMIQTPSQ 292 >1RPM-A nrPDB Length = 278 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 38/94 (40%), Gaps = 8/94 (8%) Query: 59 EKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118 E WP D G P + ++ VK+K + G V VHC AG GR + + Sbjct: 174 EIRQFHFTGWP-DHGVPYHATGLLGFVRQVKSKSPPSAGPLV-VHCSAGAGRTGCFIVID 231 Query: 119 LIESGMKYEDAIQ------FIRQKRRGAINSKQL 146 ++ + E + +R +R + +++ Sbjct: 232 IMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQ 265 >5HDE-A nrPDB Length = 307 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 11/96 (11%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA----LA 118 V+WP D P + D +SL++ K+ E + +HC AG GR + A Sbjct: 198 FHYVNWP-DHDVPSSFDSILDMISLMR-KYQEHEDVPICIHCSAGCGRTGAICAIDYTWN 255 Query: 119 LIESGMKYED-----AIQFIRQKRRGAINSKQLTYL 149 L+++G E+ IQ +R +R A+ +K+ L Sbjct: 256 LLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYEL 291 >4PVG-A nrPDB Length = 298 Score = 55.1 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHCVAGLGRAPVLVALAL--- 119 WP D G P V D+L V K V VHC AG+GR + + + Sbjct: 181 HFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 239 Query: 120 ------IESGMKYEDAIQFIRQKRRGAINSK-QLTYLE 150 ++ + IQ +R +R G + ++ Q ++ Sbjct: 240 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 277 >2GJT-A nrPDB Length = 295 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 47/107 (43%), Gaps = 11/107 (10%) Query: 63 ITVVDWPFDDGAPPPG--KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 WP D G P + + ++ +V+ + ++ G + +HC AG+GR +AL + Sbjct: 182 FNYTAWP-DHGVPTANAAESILQFVHMVRQQATKSKGPMI-IHCSAGVGRTGTFIALDRL 239 Query: 121 ESGMKYEDAIQ------FIRQKRRGAINSKQLTYLEKYRPKQRLRFK 161 ++ + + +R R + +++ Y+ ++ Q + K Sbjct: 240 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ-YIFIHQCVQLMWMK 285 >2QEP-A nrPDB Length = 304 Score = 54.7 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 37/91 (40%), Gaps = 9/91 (9%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122 + W +D G P + + D+ V + + VHC G GR+ V + ++ + Sbjct: 193 FHFLSW-YDRGVPSSSRSLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRSGTYVLIDMVLN 250 Query: 123 GMK-------YEDAIQFIRQKRRGAINSKQL 146 M ++ +R +R G + +K+ Sbjct: 251 KMAKGAKEIDIAATLEHLRDQRPGMVQTKEQ 281 >2PI7-A nrPDB Length = 312 Score = 54.7 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 40/92 (43%), Gaps = 10/92 (10%) Query: 63 ITVVDWPFDDGAPPPG--KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 WP D G P + + ++ +V+ K ++ G + +HC AG+GR +AL + Sbjct: 191 FNYTAWP-DHGVPTANAAESILQFVQMVRQKSVKSKGPMI-IHCSAGVGRTGTFIALDWL 248 Query: 121 ESGMKYEDAIQFI------RQKRRGAINSKQL 146 ++ + + + R R + +++ Sbjct: 249 LQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQ 280 >2I1Y-A nrPDB Length = 301 Score = 54.7 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 9/91 (9%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122 + WP + G P + + D+ V + + VHC G GR + + ++ + Sbjct: 192 FHFLSWPAE-GTPASTRPLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRTGTYILIDMVLN 249 Query: 123 GMK-------YEDAIQFIRQKRRGAINSKQL 146 M ++ +R +R G + SK Sbjct: 250 RMAKGVKEIDIAATLEHVRDQRPGLVRSKDQ 280 >1ZC0-A nrPDB Length = 309 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 41/112 (36%), Gaps = 9/112 (8%) Query: 46 VRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAK-FCEAPGSCVAVHC 104 VR + Y + I WP D P + ++ V+ A + VHC Sbjct: 182 VRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHC 240 Query: 105 VAGLGRAPVLVALALIESGMKYEDAIQF------IRQKRRGAINS-KQLTYL 149 AG+GR +A + +K + +R R G I + +Q +L Sbjct: 241 SAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFL 292 >3OLR-A nrPDB Length = 313 Score = 53.2 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 50/123 (40%), Gaps = 11/123 (8%) Query: 36 DLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEA 95 + +K + ++R +V ++ +WP D P + + + V+ + E Sbjct: 180 EAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDVR-CYQED 237 Query: 96 PGSCVAVHCVAGLGRAPVLVA----LALIESGMKYE-----DAIQFIRQKRRGAINSKQL 146 + +H AG GR V+ A L++ G+ E I+ +R +R + +++ Sbjct: 238 DSVPICIHSSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQ 297 Query: 147 TYL 149 L Sbjct: 298 YEL 300 >6H8S-A nrPDB Length = 301 Score = 53.2 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 14/94 (14%) Query: 67 DWP---FDDGAPPPGKVVEDWLSLVKAKFCEAPGS-CVAVHCVAGLGRAPVLVALALIES 122 WP D APP +V + + +A E P + VHC AG+GR +A ++ Sbjct: 196 SWPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQ 252 Query: 123 GMKYEDAIQF------IRQKRRGAINS-KQLTYL 149 ++ E + +RQ R G I + +Q ++ Sbjct: 253 QLRREGVVDILKTTCQLRQDRGGMIQTCEQYQFV 286 >1WCH-A nrPDB Length = 315 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 40/98 (40%), Gaps = 9/98 (9%) Query: 71 DDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA----LALIESGMKY 126 D P +D L+ + + HC AG+GR+ L+ L LI + + Sbjct: 215 PDHDTPS--QPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDF 272 Query: 127 E--DAIQFIRQKRRGAINSK-QLTYLEKYRPKQRLRFK 161 + D ++ +R +R G + ++ Q + + R + Sbjct: 273 DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQ 310 >3S3F-A nrPDB Length = 307 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 8/92 (8%) Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 WP D G P P + + ++ + + + VHC AG+GR+ + L I Sbjct: 201 RHFHFTTWP-DFGVPNPPQTLVRFVRAFRDRIGAEQ-RPIVVHCSAGVGRSGTFITLDRI 258 Query: 121 ESGMKYEDAIQFI------RQKRRGAINSKQL 146 + D + R++R + ++Q Sbjct: 259 LQQINTSDYVDIFGIVYAMRKERVWMVQTEQQ 290 >1YFO-A nrPDB Length = 302 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 39/103 (37%), Gaps = 9/103 (8%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVA------ 116 WP D G P + +L VKA + G + VHC AG+GR V Sbjct: 193 FHFTSWP-DFGVPFTPIGMLKFLKKVKACNPQYAG-AIVVHCSAGVGRTGTFVVIDAMLD 250 Query: 117 LALIESGMKYEDAIQFIRQKRRGAINSK-QLTYLEKYRPKQRL 158 + E + + IR +R + + Q ++ + + L Sbjct: 251 MMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL 293 >2C7S-A nrPDB Length = 313 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 34/91 (37%), Gaps = 10/91 (10%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG-SCVAVHCVAGLGRAPVLVALALIE 121 WP D G P + ++ VK P + VHC AG GR + + ++ Sbjct: 202 FHFTGWP-DHGVPYHATGLLSFIRRVK--LSNPPSAGPIVVHCSAGAGRTGCYIVIDIML 258 Query: 122 SGMKYEDAIQF------IRQKRRGAINSKQL 146 + E + +R +R + +++ Sbjct: 259 DMAEREGVVDIYNCVKALRSRRINMVQTEEQ 289 >2OOQ-A nrPDB Length = 286 Score = 50.9 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 33/90 (36%), Gaps = 8/90 (8%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122 WP D G P + ++ VK + VHC AG GR +A+ + Sbjct: 180 FHFTSWP-DHGVPCYATGLLGFVRQVK-FLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLD 237 Query: 123 GMKYEDAIQ------FIRQKRRGAINSKQL 146 + E + +R +R + +++ Sbjct: 238 MAENEGVVDIFNCVRELRAQRVNLVQTEEQ 267 >1WRM-A nrPDB Length = 165 Score = 50.9 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 33/139 (23%), Positives = 55/139 (39%), Gaps = 13/139 (9%) Query: 34 IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK-AKF 92 E L K T ++ V +D +G+ + P D P + + +K Sbjct: 25 AEQLSKNKVTHILSV----HDSARPMLEGVKYLCIPAAD--SPSQNLTRHFKESIKFIHE 78 Query: 93 CEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKR----RGAINSKQLT 147 C G VHC+AG+ R+ LV ++ + +EDA+ +R R +QL Sbjct: 79 CRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQ 138 Query: 148 YLEKYRPKQ-RLRFKDPHT 165 EK+ Q R K+ + Sbjct: 139 EFEKHEVHQYRQWLKEEYG 157 >4YR8-G nrPDB Length = 167 Score = 49.7 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 19/104 (18%) Query: 54 DKTPLEKDGITVV-----DWPFDDGAPPP--------GKVVEDWLSLVKAKF-----CEA 95 +K ++++GI V P D P E L + +A Sbjct: 42 NKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKA 101 Query: 96 PGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRR 138 CV VHC+AG+ R+ + +++ M ++A +F+++KR Sbjct: 102 SNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP 145 >1YGU-A nrPDB Length = 610 Score = 49.7 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 8/93 (8%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES 122 I WP D G P ++ V A F + VH AG+GR + + + Sbjct: 191 IQFTSWP-DHGVPEDPHLLLKLRRRVNA-FSNFFSGPIVVHSSAGVGRTGTYIGIDAMLE 248 Query: 123 GMKYEDAIQF------IRQKRRGAINSKQLTYL 149 G++ E+ + +R++R + + L Sbjct: 249 GLEAENKVDVYGYVVKLRRQRCLMVQVEAQYIL 281 Score = 40.1 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 38/105 (36%), Gaps = 17/105 (16%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS---------CVAVHCVAGLGRAPVL 114 +W + P K + + +VK K + S + +HC G + + Sbjct: 498 QYTNWSVEQ-LPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIF 556 Query: 115 VALALIESGMKYEDAIQFI------RQKRRGAINS-KQLTYLEKY 152 AL + + E+ + R+ R G +++ +Q +L Sbjct: 557 CALLNLLESAETEEVVDIFQVVKALRKARLGMVSTFEQYQFLYDV 601 >2R0B-A nrPDB Length = 154 Score = 49.3 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 25 PTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84 P ++ + + + L+K+G T ++ + + + ++ + + + D A P + + + Sbjct: 17 PYSSAMKSKLPVLQKHGITHIICIRQNI-EANFIKPNFQQLFRYLVLDIADNPVENIIRF 75 Query: 85 LSLVKAKF--CEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRR 138 + K G V VH AG+ R+ V ++E+ GMKY DA +++++R Sbjct: 76 FPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRF 132 >4RHG-A nrPDB Length = 306 Score = 49.3 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 9/90 (10%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV----ALA 118 + V WP + G P ++++ V++ ++ V VH AG+GR VLV A+ Sbjct: 201 LQYVAWP-EHGVPDDSSDFLEFVNYVRSLRVDSE--PVLVHSSAGIGRTGVLVTMETAMC 257 Query: 119 LIESGMKY--EDAIQFIRQKRRGAINSKQL 146 L E + D ++ +R +R + + Sbjct: 258 LTERNLPIYPLDIVRKMRDQRAMMVQTSSQ 287 >4IKC-A nrPDB Length = 281 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 32/142 (22%), Positives = 54/142 (38%), Gaps = 25/142 (17%) Query: 19 FLITHNPTNATLSTFIEDLK--KYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPP 76 +IT + + I DLK ++G VR C T WP + G P Sbjct: 150 IVITKLMEDVQIDWTIRDLKIERHGDCMTVRQCNFT--------------AWP-EHGVPE 194 Query: 77 PGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQ----- 131 + ++ LV+A + VH AG+GR V +AL + + D + Sbjct: 195 NSAPLIHFVKLVRASRAHDTTPMI-VHSSAGVGRTGVFIALDHLTQHINDHDFVDIYGLV 253 Query: 132 -FIRQKRRGAINS-KQLTYLEK 151 +R +R + + Q +L + Sbjct: 254 AELRSERMCMVQNLAQYIFLHQ 275 >2Q47-A nrPDB Length = 151 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 3/85 (3%) Query: 37 LKKYGATTVVRVCEVTY---DKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFC 93 L+ G +++ +C Y + L+ +GI + + + P + + + + Sbjct: 29 LQTLGLRSIIYLCPEPYPESNLQFLKSNGIRLFQFGIEGNKEPFVNIPDHKIRMALKVLL 88 Query: 94 EAPGSCVAVHCVAGLGRAPVLVALA 118 + V +HC G R LV Sbjct: 89 DEKNHPVLIHCKRGKHRTGCLVGCL 113 >4GFV-A nrPDB Length = 297 Score = 47.0 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 48/123 (39%), Gaps = 12/123 (9%) Query: 38 KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97 K ++R +VT+ K + + WP D G P + + + + + Sbjct: 162 KWLNEDIMLRTLKVTFQKESRSVYQLQYMSWP-DRGVPSSPDHMLAMVEEAR-RLQGSGP 219 Query: 98 SCVAVHCVAGLGRAPVLVALALIESGMKYE---------DAIQFIRQKRRGAINS-KQLT 147 + VH AG GR VL + + + + D + +R++R A+ + +Q Sbjct: 220 EPLCVHSSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYR 279 Query: 148 YLE 150 +L Sbjct: 280 FLY 282 >5AWX-A nrPDB Length = 298 Score = 47.0 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 35/89 (39%), Gaps = 8/89 (8%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123 WP D G P V ++ A G V VHC AG+GR + L + Sbjct: 193 HYTQWP-DMGVPEYSLPVLTFVRKAAYAKRHAVG-PVVVHCSAGVGRTGTYIVLDSMLQQ 250 Query: 124 MKYEDAIQF------IRQKRRGAINSKQL 146 +++E + IR +R + +++ Sbjct: 251 IQHEGTVNIFGFLKHIRSQRNYLVQTEEQ 279 >4KYQ-A nrPDB Length = 208 Score = 46.6 bits (109), Expect = 5e-06, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 3/82 (3%) Query: 59 EKDGITVVDWPFDDGAPPPG-KVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRA-PVLVA 116 ++ GI + P D P + +S ++ E G V VHC AGLGRA V +A Sbjct: 74 KELGIRHMRRPAKDFDPLSLRSQLPKAVSSLEWAVSEGKG-RVYVHCSAGLGRAPGVSIA 132 Query: 117 LALIESGMKYEDAIQFIRQKRR 138 M A + KR Sbjct: 133 YMYWFCDMNLNTAYDTLVSKRP 154 >3F41-A nrPDB Length = 629 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 3/73 (4%) Query: 46 VRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCV 105 V++ V ++ +EK+G+ D P ++++++ + A + HC Sbjct: 482 VKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANA---WLHFHCQ 538 Query: 106 AGLGRAPVLVALA 118 AG GR +A+ Sbjct: 539 AGAGRTTAYMAMY 551 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 28 ATLSTFIEDLKKYGAT---TVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84 +T+ + K V +V ++ +++ G D P V+ + Sbjct: 163 STVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKF 222 Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG---MKYEDAIQFIRQKRRGAI 141 L K+ + + HC AG+GR + + + I + ++D IQ RQK G + Sbjct: 223 LEFYKSL---PKDAWLHYHCYAGMGRTTIFMVMHDILKNAKDVSFDDIIQ--RQKLIGIV 277 Query: 142 ----------NSKQLTYLEKYRPKQR 157 N + Y+E+Y+ Q Sbjct: 278 DLSEIPDKKKNYGRKAYIERYQFVQH 303 >2NLK-A nrPDB Length = 627 Score = 45.9 bits (107), Expect = 9e-06, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 33/89 (37%), Gaps = 8/89 (8%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123 WP D G P V ++ + V VHC AG+GR + + + Sbjct: 197 HYTQWP-DMGVPEYALPVLTFVRR-SSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQ 254 Query: 124 MKYEDAIQF------IRQKRRGAINSKQL 146 +K + + IR +R + +++ Sbjct: 255 IKDKSTVNVLGFLKHIRTQRNYLVQTEEQ 283 >2PBN-A nrPDB Length = 313 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 33/89 (37%), Gaps = 8/89 (8%) Query: 64 TVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG 123 WP D G P V ++ + V VHC AG+GR + + + Sbjct: 205 HYTQWP-DMGVPEYALPVLTFVRR-SSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQ 262 Query: 124 MKYEDAIQF------IRQKRRGAINSKQL 146 +K + + IR +R + +++ Sbjct: 263 IKDKSTVNVLGFLKHIRTQRNYLVQTEEQ 291 >3RGQ-A nrPDB Length = 156 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 30/138 (21%), Positives = 47/138 (34%), Gaps = 7/138 (5%) Query: 19 FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTY---DKTPLEKDGITVVDWPFDDGA- 74 L+ P + D G T+ E + +K G+ + D Sbjct: 10 VLLGALPLKNMTRRLVLDENVRGVITMNEEYETRFLCNTSKEWKKAGVEQLRLSTVDMTG 69 Query: 75 PPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFI 133 P + + A +A G CV VH AG R+ +VA LI+ E+AI+ I Sbjct: 70 VPTLANLHKGVQF--ALKYQALGQCVYVHSKAGRSRSATMVAAYLIQVHNWSPEEAIEAI 127 Query: 134 RQKRRGAINSKQLTYLEK 151 + R + K Sbjct: 128 AKIRSHISIRPSQLEVLK 145 >3LJ8-A nrPDB Length = 146 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 40/107 (37%), Gaps = 7/107 (6%) Query: 34 IEDLKKYGATTVVRVCEVTYDKTPLEKDG-ITVVDWPFDDGAPPPGK-VVEDWLSLVKAK 91 +E L K G ++ V + EK+G P D + + + Sbjct: 21 LESLAKLGIRYILNVTPNLPN--FFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEA 78 Query: 92 FCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137 V VHC+AG+ R+ + L++ + DA +++K+ Sbjct: 79 LS--QNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 123 >2G6Z-A nrPDB Length = 211 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 55/132 (41%), Gaps = 14/132 (10%) Query: 8 APVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVD 67 PVE+ + FL + +A+ F+ +L T ++ V T + + Sbjct: 5 GPVEI----LPFLYLGSAYHASKCEFLANLH---ITALLNVSRRTSEACMTH---LHYKW 54 Query: 68 WPFDD-GAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG-MK 125 P +D ++ + + E G V VH AG+ R+P + L+++ + Sbjct: 55 IPVEDSHTADISSHFQEAIDFID-CVREK-GGKVLVHSEAGISRSPTICMAYLMKTKQFR 112 Query: 126 YEDAIQFIRQKR 137 ++A +I+Q+R Sbjct: 113 LKEAFDYIKQRR 124 >6N8N-Y nrPDB Length = 364 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 54/159 (33%), Gaps = 29/159 (18%) Query: 17 MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDG-AP 75 +R +I H P A + T ++ V + L + G T+ + P DD Sbjct: 24 IRPIIDHRPLGAEFN----------ITHILSVIKFQVIPEYLIRKGYTLKNIPIDDDDVT 73 Query: 76 PPGKVVEDWLSLVKAKF---------------CEAPGSCVAVHCVAGLGRAPVLVALALI 120 + ++ + + V HC AGL R+ + L+ Sbjct: 74 DVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLM 133 Query: 121 ES-GMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158 G+ A+ +++K+ ++E+ +++ Sbjct: 134 YRYGLSLSMAMHAVKRKKPS--VEPNENFMEQLHLFEKM 170 >4MBB-A nrPDB Length = 184 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 39/112 (34%), Gaps = 3/112 (2%) Query: 49 CEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVA 106 Y K + + + P + + + V E + + VH Sbjct: 72 YTQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHSTH 131 Query: 107 GLGRAPVLVALALIE-SGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQR 157 GL R L+ LI+ G++ +DAI+ + R + + + P ++ Sbjct: 132 GLNRTGYLICRYLIDVEGVRPDDAIELFNRCRGHCLERQNYIEDLQNGPIRK 183 >1M3G-A nrPDB Length = 145 Score = 43.2 bits (100), Expect = 5e-05, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 36/89 (40%), Gaps = 6/89 (6%) Query: 63 ITVVDWPFDDG-APPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI- 120 P +D ++ + + + G V VH AG+ R+ + L+ Sbjct: 48 FRYKSIPVEDNQMVEISAWFQEAIGFIDW--VKNSGGRVLVHSQAGISRSATICLAYLMQ 105 Query: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYL 149 ++ ++A F++Q+R + S +++ Sbjct: 106 SRRVRLDEAFDFVKQRR--GVISPNFSFM 132 >4NX8-A nrPDB Length = 293 Score = 43.2 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 30/80 (37%), Gaps = 3/80 (3%) Query: 56 TPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV 115 + + G V D P V+ ++ V+A + V HC AG GR + Sbjct: 161 SMIRTGGHQYVRLTVTDHVRPVDSEVDRFIESVRAL---PENAWVHFHCRAGKGRTTTFM 217 Query: 116 ALALIESGMKYEDAIQFIRQ 135 L + K + + I++ Sbjct: 218 VLYDMLKNAKTDSFEEIIKR 237 >6DR7-A nrPDB Length = 306 Score = 43.2 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 38/104 (36%), Gaps = 21/104 (20%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG-------SCVA--------VHCVAG 107 + V WP D P +V + SLV S VA +HC AG Sbjct: 187 VHVTTWP--DFGVPESEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAG 244 Query: 108 LGRAPVLVALALI----ESGMKYEDAIQFIRQKRRGAINSKQLT 147 +GR L+ + S + ED + +R +R G + K Sbjct: 245 VGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQ 288 >4TVV-A nrPDB Length = 314 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 21/59 (35%), Gaps = 3/59 (5%) Query: 60 KDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA 118 K G D P V+ ++L+K + VHC G GR + A+ Sbjct: 185 KKGFDYYRIFISDHRAPLDSEVDALVALIKN---NPEDTWYHVHCRGGKGRTTTVFAMF 240 >1ZZW-A nrPDB Length = 149 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Query: 97 GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149 G + +HC AG+ R+ +V L++ M DA +F++ KR I S L ++ Sbjct: 83 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 134 >4B04-A nrPDB Length = 160 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 42/106 (39%), Gaps = 3/106 (2%) Query: 35 EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK--AKF 92 +L++ G T V+ + TP +G+ + + P + + + + Sbjct: 22 RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRA 81 Query: 93 CEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKR 137 PG + VH G+ R+ LV L+ + +AI+ ++ R Sbjct: 82 LSQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 127 >5GTJ-A nrPDB Length = 181 Score = 42.0 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 42/106 (39%), Gaps = 3/106 (2%) Query: 35 EDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK--AKF 92 +L++ G T V+ + TP +G+ + + P + + + + Sbjct: 43 RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRA 102 Query: 93 CEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKR 137 PG + VH G+ R+ LV L+ + +AI+ ++ R Sbjct: 103 LSQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 148 >2OUD-A nrPDB Length = 177 Score = 42.0 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Query: 97 GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYL 149 G + +HC AG+ R+ +V L++ M DA +F++ KR I S L ++ Sbjct: 87 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 138 >1J4X-A nrPDB Length = 184 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 45/119 (37%), Gaps = 9/119 (7%) Query: 27 NATLSTFIEDLKKYGATTVVRVCE------VTYDKTPLEKDGITVVDWPFDDGAPPPGKV 80 NA+++ I L+K G T V+ E V + + GIT + +D Sbjct: 40 NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSA 99 Query: 81 -VEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137 E + + V VH G R+P LV L+ M + A+ +RQ R Sbjct: 100 YFERAADFIDQALAQK-NGRVLVHSREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNR 157 >4JMK-A nrPDB Length = 152 Score = 40.9 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 48/124 (38%), Gaps = 33/124 (26%) Query: 45 VVRVCEVTY--------DKTPLEKDGITVV-----DWPFDDGAPPPG-----------KV 80 + R+ Y +K + ++GI+ V P D + Sbjct: 3 LTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEK 62 Query: 81 VEDWLS-----LVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIR 134 + WL + KAK V VH +AG+ R+ + ++++ GM +DA +F++ Sbjct: 63 LLPWLDKSIEFIDKAKLSS---CQVIVHSLAGISRSATIAIAYIMKTMGMSSDDAYRFVK 119 Query: 135 QKRR 138 +R Sbjct: 120 DRRP 123 >1G4W-R nrPDB Length = 383 Score = 40.9 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 26/67 (38%), Gaps = 10/67 (14%) Query: 63 ITVVDWPFDDGAP-PPGKVVEDWLSLVKAKFCEAPGSCVA-------VHCVAGLGRAPVL 114 + V +WP D P P +E VK + +HC+ G+GR + Sbjct: 274 LHVKNWP--DHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTM 331 Query: 115 VALALIE 121 A +++ Sbjct: 332 AAALVLK 338 >5M43-A nrPDB Length = 225 Score = 40.9 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 20/129 (15%), Positives = 44/129 (34%), Gaps = 24/129 (18%) Query: 34 IEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDD--------GAPPPGKVVEDWL 85 +K++ T ++ V + T D+ + + DD P + ++ L Sbjct: 23 ARLIKEHRITHILSVIDHTVDRENEAFRHVKHLSIDIDDMEDQDILIHLPKIVRFIDSGL 82 Query: 86 SLVKAKFCEA--PGSCVAVHCVAGLGRAPVLVALALIES----------GMKYEDAI--- 130 + A V VHC G R+ + L+ + ++A+ Sbjct: 83 RGIDPSDSSAVASPGVVLVHCAMGKSRSVTAIIAYLLWKYPYRFGKSDPNISAKEAVSRA 142 Query: 131 -QFIRQKRR 138 +++R+ R Sbjct: 143 LEWVRETRP 151 >5XJV-A nrPDB Length = 185 Score = 40.1 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 35/89 (39%), Gaps = 6/89 (6%) Query: 50 EVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLG 109 + + + G+ D P D + D++ + PG+ V VH V G+ Sbjct: 80 GPDFYGSSVSYLGVPAHDLPDFDISA-YFSSAADFIH----RALNTPGAKVLVHSVVGVS 134 Query: 110 RAPVLVALALI-ESGMKYEDAIQFIRQKR 137 R+ LV L+ + A+ +RQ R Sbjct: 135 RSATLVLAYLMLHQRLSLRQAVITVRQHR 163 >2Y96-A nrPDB Length = 219 Score = 40.1 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 13/95 (13%) Query: 48 VCEVTYDKTP-LEKDGITVVDWPFDDGAP---PPGKVVEDWLSLVKAKFCEAPGSCVAVH 103 Y + ++ G+ D P D + P ++ LS S + VH Sbjct: 94 DTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALS--------DDHSKILVH 145 Query: 104 CVAGLGRAPVLVALAL-IESGMKYEDAIQFIRQKR 137 CV G R+ LV L I M DAIQ + + R Sbjct: 146 CVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNR 180 >1YZ4-A nrPDB Length = 160 Score = 39.7 bits (91), Expect = 6e-04, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 11/110 (10%) Query: 34 IEDLKKYG---ATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVK- 89 +DL + G T ++ + E + L+ IT + P D P + + + + Sbjct: 23 AKDLDQLGRNKITHIISIHESP--QPLLQD--ITYLRIPVAD--TPEVPIKKHFKECINF 76 Query: 90 AKFCEAPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRR 138 C G VH AG+ R+ +V ++ +G+ + D ++ I+ R Sbjct: 77 IHCCRLNGGNCLVHSFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP 126 >2RF6-A nrPDB Length = 176 Score = 39.7 bits (91), Expect = 6e-04, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 44/114 (38%), Gaps = 11/114 (9%) Query: 48 VCEVTYDKTPLEKDGITVVDWPF-DDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVA 106 V +T DK L I ++ P DD K +D + + C+ V VH A Sbjct: 60 VLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSK--CDQRNEPVLVHSAA 117 Query: 107 GLGRAPVLVALALIESGMKYEDAIQFI------RQKRRGAINSK--QLTYLEKY 152 G+ R+ ++ L+ + + F+ R R + + + +EKY Sbjct: 118 GVNRSGAMILAYLMSKNKESLPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKY 171 >6I28-A nrPDB Length = 168 Score = 39.7 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 40/124 (32%), Gaps = 4/124 (3%) Query: 33 FIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKF 92 F+ +++ + DG + DD + L Sbjct: 33 FVRQNNVGCVVSLIDSDVAPIKRALYLPDGDHLHVHCEDDAKCGALADNLEMLFNYLWLK 92 Query: 93 CEAPGSCVAVHCVAGLGRAPVLVALALIESG-MKYEDAIQFIRQKRRGAINSKQLTYLEK 151 V +HC AG+ R+ L ++ + + YE A Q++ KR ++E Sbjct: 93 IHNEHKTVLIHCHAGVSRSATLAIYYIMRTNQIDYEQAFQYVYGKR---AVHPSEHFVEL 149 Query: 152 YRPK 155 + K Sbjct: 150 LKGK 153 >6D67-A nrPDB Length = 520 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 39/88 (44%), Gaps = 6/88 (6%) Query: 64 TVVDWPFDD-GAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-E 121 P +D + + + + + G V VH AG+ R+ + L+ Sbjct: 419 QYKSIPVEDNHKADISSWFNEAIDFIDS--IKNAGGRVFVHSQAGISRSATICLAYLMRT 476 Query: 122 SGMKYEDAIQFIRQKRRGAINSKQLTYL 149 + +K ++A +F++Q+R +I S +++ Sbjct: 477 NRVKLDEAFEFVKQRR--SIISPNFSFM 502 >4Y2E-A nrPDB Length = 149 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 41/104 (39%), Gaps = 7/104 (6%) Query: 37 LKKYGATTVVRVCEVTYDKTPLEKDG-ITVVDWPFDDGAPPPGKVV-EDWLSLVKAKFCE 94 L KYG ++ V + E G T P D + +S + + Sbjct: 27 LGKYGIKYILNVTPNLPNA--FEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSK 84 Query: 95 APGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKR 137 G V VH +AG+ R+ + L++ + DA F+++K+ Sbjct: 85 KCG--VLVHSLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKK 126 >2ESB-A nrPDB Length = 188 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 32/94 (34%), Gaps = 8/94 (8%) Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKF--CEAPGSCVAVHCVAGLGRAPVLVALA 118 + I + P D P + D+ + E +HC AG+ R+ L Sbjct: 62 EDIQYMQVPVADS---PNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118 Query: 119 LI-ESGMKYEDAIQFIRQKRRGAINSKQLTYLEK 151 L+ M DA + + R I + E+ Sbjct: 119 LMKYHAMSLLDAHTWTKSCRP--IIRPNSGFWEQ 150 >3EZZ-A nrPDB Length = 144 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 32/53 (60%), Gaps = 3/53 (5%) Query: 98 SCVAVHCVAGLGRAPVL-VALALIESGMKYEDAIQFIRQKRRGAINSKQLTYL 149 V VH AG+ R+ + +A +++ ++ E+A +F++Q+R +I S +++ Sbjct: 82 GRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRR--SIISPNFSFM 132 >2M3V-A nrPDB Length = 193 Score = 37.8 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Query: 83 DWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA-LIESGMKYEDAIQFIRQKRRG 139 + LS+++ V +HC G R + A+ ++ G + A++ +++ G Sbjct: 86 EVLSVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALEEMQRGGFG 143 >3D1Q-A nrPDB Length = 340 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 28/69 (40%), Gaps = 3/69 (4%) Query: 47 RVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVA 106 RV +V ++ E G+ D P + ++ +L+ + + + HC A Sbjct: 192 RVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTL---PQDAWLHFHCEA 248 Query: 107 GLGRAPVLV 115 G+GR + Sbjct: 249 GVGRTTAFM 257 >2WGP-A nrPDB Length = 190 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 37/103 (35%), Gaps = 5/103 (4%) Query: 37 LKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP 96 L+ G T +V T + V P D P + D ++ K Sbjct: 47 LQARGITCIV---NATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVAD-KIHSVSRK 102 Query: 97 GSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAIQFIRQKRR 138 VHC AG+ R+ L L++ + +A +++ +R Sbjct: 103 HGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 145 >1MKP-A nrPDB Length = 144 Score = 36.6 bits (83), Expect = 0.005, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 46/132 (34%), Gaps = 14/132 (10%) Query: 9 PVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDG-ITVVD 67 PVE+ + FL ++T +E+ G ++ V + E G Sbjct: 4 PVEI----LPFLYLGCAKDSTNLDVLEEF---GIKYILNVTPNLPNL--FENAGEFKYKQ 54 Query: 68 WPFDDGAPPPGKVV-EDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIES-GMK 125 P D + +S + V VH +AG+ R+ + L++ + Sbjct: 55 IPISDHWSQNLSQFFPEAISFIDE--ARGKNCGVLVHSLAGISRSVTVTVAYLMQKLNLS 112 Query: 126 YEDAIQFIRQKR 137 DA ++ K+ Sbjct: 113 MNDAYDIVKMKK 124 >4R0S-A nrPDB Length = 218 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 83 DWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALA-LIESGMKYEDAIQFIRQKRRG 139 + LS+++ V +HC G R + A+ ++ G + A++ ++ G Sbjct: 111 EVLSVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALEEMQHGGFG 168 >4R30-A nrPDB Length = 184 Score = 35.8 bits (81), Expect = 0.008, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 34/104 (32%), Gaps = 8/104 (7%) Query: 56 TPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV 115 ++G+ + P D + + + E G V VH AG+GR+ V Sbjct: 72 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEK-GHIVYVHSNAGVGRSTAAV 130 Query: 116 A-LALIESGMKYEDAIQFIRQKRRG------AINSKQLTYLEKY 152 G F+ KR A+ Q + +K+ Sbjct: 131 CGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALARAQEDFFQKF 174 >4RKK-A nrPDB Length = 332 Score = 35.8 bits (81), Expect = 0.009, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 34/104 (32%), Gaps = 8/104 (7%) Query: 56 TPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLV 115 ++G+ + P D + + + E G V VH AG+GR+ V Sbjct: 222 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEK-GHIVYVHSNAGVGRSTAAV 280 Query: 116 A-LALIESGMKYEDAIQFIRQKRRG------AINSKQLTYLEKY 152 G F+ KR A+ Q + +K+ Sbjct: 281 CGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALARAQEDFFQKF 324 >6E3B-A nrPDB Length = 169 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 17/128 (13%), Positives = 31/128 (24%) Query: 25 PTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDW 84 P S E LK ++ + L+ GI + P + Sbjct: 23 PRQENFSFLHERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHL 82 Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSK 144 L+ + +H G R L+ R+ + Sbjct: 83 LTKALEIVLNPANQPILIHSNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARAL 142 Query: 145 QLTYLEKY 152 ++E Y Sbjct: 143 DQQFIEMY 150 >2HCM-A nrPDB Length = 164 Score = 34.3 bits (77), Expect = 0.028, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 4/79 (5%) Query: 62 GITVVDWP-FDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 G+ + P FDD A +E + ++A G V+C G R+ + L+ Sbjct: 55 GVAELRVPVFDDPAEDLLTHLEPTCAAMEAAVR--DGGSCLVYCKNGRSRSAAVCTAYLM 112 Query: 121 -ESGMKYEDAIQFIRQKRR 138 G + A Q ++ R Sbjct: 113 RHRGHSLDRAFQMVKSARP 131 >5Y15-A nrPDB Length = 197 Score = 32.8 bits (73), Expect = 0.079, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 30/79 (37%), Gaps = 4/79 (5%) Query: 62 GITVVDWP-FDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 G+ + P FDD A +E + ++A G V+ G R+ + L+ Sbjct: 83 GVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVR--AGGACLVYSKNGRSRSAAVCTAYLM 140 Query: 121 -ESGMKYEDAIQFIRQKRR 138 G+ A Q ++ R Sbjct: 141 RHRGLSLAKAFQMVKSARP 159 >2OZ5-A nrPDB Length = 296 Score = 32.4 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 24/60 (40%), Gaps = 10/60 (16%) Query: 95 APGSCVAVHCVAGLGRAPVLVALALIESG----------MKYEDAIQFIRQKRRGAINSK 144 A G V HC AG R +VAL L G ++ D++ +R + I + Sbjct: 171 AAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQR 230 >5NCR-A nrPDB Length = 181 Score = 32.0 bits (71), Expect = 0.12, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 24/70 (34%), Gaps = 1/70 (1%) Query: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 GIT P D + L + A+ EA VH VAG+ R+ ++ Sbjct: 70 AGITAYHIPLRDDDKTNIASIMPALVKLLARL-EAEQKPTLVHSVAGVNRSGAAAMGYVM 128 Query: 121 ESGMKYEDAI 130 + + Sbjct: 129 HKRLAENPTM 138 >4D3P-A nrPDB Length = 147 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 37/107 (34%), Gaps = 18/107 (16%) Query: 50 EVTYDKTPLEKDGITVV--------DWPFDDGAPPPGKVVE----DWLSLVKAKF----- 92 + +D L+K+ +T + + D +++ + LS F Sbjct: 21 DAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEE 80 Query: 93 CEAPGSCVAVHCVAGLGR-APVLVALALIESGMKYEDAIQFIRQKRR 138 + V VH AG+ R A +++ + + A ++ R Sbjct: 81 AKRKDGVVLVHANAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARP 127 >2QFY-A nrPDB Length = 427 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 45/131 (34%), Gaps = 8/131 (6%) Query: 1 MARMNRPAPVE-VSYKHMRFLITH--NPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTP 57 MA N +E ++ + I N +T +T ++ V E Y K+ Sbjct: 196 MAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQY-KSK 254 Query: 58 LEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVAL 117 E+ GI DD K ++ +K + VA G G ++ ++ Sbjct: 255 FEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVA----QGFGSLGLMTSI 310 Query: 118 ALIESGMKYED 128 + G +E Sbjct: 311 LVTPDGKTFES 321 >4CBI-A nrPDB Length = 516 Score = 30.8 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 33/95 (34%), Gaps = 9/95 (9%) Query: 1 MARMNRPAPVEVSYKHMR----FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKT 56 MAR + P P++++Y L T+ ++ A + T Sbjct: 415 MARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDTY-DNYTFLNARKLGDDVPPYVYAT 473 Query: 57 PLEKDGITV--VDWPFD--DGAPPPGKVVEDWLSL 87 E + + +DWP G G+ ++ + L Sbjct: 474 EDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGL 508 >5WSO-A nrPDB Length = 476 Score = 30.5 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 32/94 (34%), Gaps = 8/94 (8%) Query: 1 MARMNRPAPVEVSYKHMR----FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKT 56 MAR + P P++++Y L T+ E+ A + V T Sbjct: 383 MARTDHPEPIQLAYNSYEVQVPVLFPKIRNGEVTDTY-ENYSFLNARKLGEDVPVYIYAT 441 Query: 57 PLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKA 90 E + ++ + D P + V + +K Sbjct: 442 EDEDLAVDLLGLDWPD---PGNQQVVETGKALKQ 472 >5WX1-A nrPDB Length = 733 Score = 29.7 bits (65), Expect = 0.65, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 9/95 (9%) Query: 1 MARMNRPAPVEVSYKHMR----FLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKT 56 MAR + P P++++Y L ++ ++ A + T Sbjct: 640 MARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDSY-DNYTFLNARKLGDDVPPYVYAT 698 Query: 57 PLEKDGITV--VDWPFD--DGAPPPGKVVEDWLSL 87 E + + +DWP G G+ ++ + L Sbjct: 699 EDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGL 733 >4KI9-A nrPDB Length = 163 Score = 29.7 bits (65), Expect = 0.68, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 6/85 (7%) Query: 73 GAPPPGKVVEDWLSLVKAKFCE-----APGSCVAVHCVAGLGRAPVLVALALIES-GMKY 126 P K D LS + A G V VH AG+ R+ ++ L+++ + + Sbjct: 53 FVPALDKPETDLLSHLDRAVAFIGQARAEGRAVLVHSHAGVSRSVAIITAFLMKTDQLPF 112 Query: 127 EDAIQFIRQKRRGAINSKQLTYLEK 151 E A + ++ + A ++ + K Sbjct: 113 EKAYEKLQILKPEAKMNEGFEWQLK 137 >5MIO-C nrPDB Length = 573 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLS----TFIEDLKKYGATTVVRVCEVTYDKT 56 M RM R + S+ + F ATL T + ++++ VR + +K Sbjct: 1 MGRMKRAQEYDSSFPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVR--KRPLNKQ 58 Query: 57 PLEKDGITVVDWP 69 L K I V+ P Sbjct: 59 ELAKKEIDVISIP 71 >2REO-A nrPDB Length = 305 Score = 28.1 bits (61), Expect = 1.7, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 32/100 (32%), Gaps = 8/100 (8%) Query: 7 PAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYD--KTPLEKDGIT 64 P VSY H + + P L F E V +D K + Sbjct: 142 PKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKV-----VGGSWFDHVKGWWAAKDMH 196 Query: 65 -VVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVH 103 ++ ++D P + +E L ++ E + + H Sbjct: 197 RILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYH 236 >3R2N-A nrPDB Length = 138 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 7/76 (9%) Query: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRA--PVLVALALIESGMKYEDAIQFIRQKRRGAIN 142 S++ A + G VAV+CV G G + P + YE ++ + Sbjct: 63 CSMISALYATGGGRLVAVYCVDGNGDSLMPCGRC-----RQLLYEHGGPELKIMTPKGVQ 117 Query: 143 SKQLTYLEKYRPKQRL 158 + + + P++R+ Sbjct: 118 TMAQLLPQAFNPQERI 133 >1KF9-A nrPDB Length = 191 Score = 27.8 bits (60), Expect = 2.7, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 17/44 (38%) Query: 53 YDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAP 96 YD ++GI + +DG+P G++ + S Sbjct: 111 YDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDD 154 >4PYH-A nrPDB Length = 294 Score = 27.4 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 28/76 (36%), Gaps = 1/76 (1%) Query: 63 ITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-E 121 I + D ++ + K + G VH AG+GRAP + + Sbjct: 72 IQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWV 131 Query: 122 SGMKYEDAIQFIRQKR 137 G K +A + + KR Sbjct: 132 QGYKLMEAHKLLMSKR 147 >5A94-A nrPDB Length = 365 Score = 27.4 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%) Query: 52 TYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97 K P+E++GI P+ A P K +++ L K+ A Sbjct: 238 PIKKAPIEREGIAYAAHPYPQKAKPEVKNDKNFFKLWDEKWGFAAD 283 >6OIX-A nrPDB Length = 505 Score = 27.0 bits (58), Expect = 3.9, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 26/68 (38%) Query: 4 MNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGI 63 +N PA + K F + N T T ++++ G + + LE G+ Sbjct: 40 INSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGL 99 Query: 64 TVVDWPFD 71 + PF+ Sbjct: 100 DELTGPFE 107 >1OBQ-A nrPDB Length = 181 Score = 26.6 bits (57), Expect = 5.1, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 17 MRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDG 62 +F +T+NP + G V+ + YD L+++G Sbjct: 36 YQFALTNNPYQLIEKCVRNEYSFDGKQFVIESTGIAYDGNLLKRNG 81 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.130 0.348 Lambda K H 0.267 0.0402 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,412,289 Number of Sequences: 36641 Number of extensions: 222014 Number of successful extensions: 1003 Number of sequences better than 10.0: 125 Number of HSP's better than 10.0 without gapping: 140 Number of HSP's successfully gapped in prelim test: 66 Number of HSP's that attempted gapping in prelim test: 806 Number of HSP's gapped (non-prelim): 215 length of query: 173 length of database: 10,336,785 effective HSP length: 90 effective length of query: 83 effective length of database: 7,039,095 effective search space: 584244885 effective search space used: 584244885 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 55 (25.8 bits)