BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O70351 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1E3W-A nrPDB 520 e-148 2O23-A nrPDB 464 e-131 3PPI-A nrPDB 194 5e-50 4NBV-A nrPDB 130 4e-31 2HQ1-A nrPDB 129 2e-30 4JRO-A nrPDB 119 2e-27 4CQL-A nrPDB 118 3e-27 3RSH-A nrPDB 115 2e-26 4NBT-A nrPDB 115 3e-26 4KMS-A nrPDB 114 3e-26 3WOH-A nrPDB 110 5e-25 1NFF-A nrPDB 109 1e-24 4DMM-A nrPDB 108 2e-24 5CDY-A nrPDB 108 3e-24 2PNF-A nrPDB 108 3e-24 2UVD-A nrPDB 107 4e-24 4CQM-B nrPDB 107 5e-24 4RZH-A nrPDB 106 8e-24 3EZL-A nrPDB 105 2e-23 3VZS-A nrPDB 105 2e-23 3OSU-A nrPDB 105 2e-23 5IZ4-A nrPDB 104 3e-23 5ITV-A nrPDB 103 9e-23 2CFC-A nrPDB 103 1e-22 5T5Q-A nrPDB 102 1e-22 2CDH-G nrPDB 102 1e-22 2HSD-A nrPDB 100 4e-22 4IS3-A nrPDB 100 1e-21 1Q7C-A nrPDB 99 2e-21 4RZI-B nrPDB 99 2e-21 1GEE-A nrPDB 98 4e-21 4K6F-A nrPDB 97 6e-21 3EMK-A nrPDB 97 8e-21 3U5T-A nrPDB 96 2e-20 3AUT-A nrPDB 95 3e-20 2C07-A nrPDB 95 3e-20 1HXH-A nrPDB 93 1e-19 1UZM-A nrPDB 92 2e-19 2NM0-A nrPDB 92 3e-19 3FTP-A nrPDB 91 3e-19 2Q2Q-A nrPDB 91 4e-19 3V2H-A nrPDB 91 6e-19 3LYL-A nrPDB 90 1e-18 1GEG-A nrPDB 88 4e-18 3F9I-A nrPDB 88 5e-18 4IIN-A nrPDB 87 9e-18 5JS6-A nrPDB 86 1e-17 3WTC-A nrPDB 85 4e-17 5VT6-A nrPDB 84 6e-17 5ILO-A nrPDB 84 8e-17 4BO1-A nrPDB 83 9e-17 3RWB-A nrPDB 83 9e-17 5OJG-A nrPDB 83 9e-17 2PH3-A nrPDB 83 1e-16 3V2G-A nrPDB 83 1e-16 2GDZ-A nrPDB 83 1e-16 5U9P-A nrPDB 82 2e-16 5YSS-A nrPDB 81 4e-16 4M8S-A nrPDB 81 4e-16 3GRP-A nrPDB 80 7e-16 3OEC-A nrPDB 79 1e-15 1AE1-A nrPDB 79 2e-15 5OVJ-A nrPDB 79 2e-15 5OVL-A nrPDB 79 2e-15 4FC7-A nrPDB 78 3e-15 4DBZ-A nrPDB 78 3e-15 2BGM-A nrPDB 78 4e-15 5EJ2-A nrPDB 77 1e-14 2AE2-A nrPDB 76 1e-14 3WYE-A nrPDB 74 5e-14 6NRP-A nrPDB 74 8e-14 2EW8-A nrPDB 74 8e-14 4TRR-A nrPDB 73 1e-13 1AHH-A nrPDB 73 1e-13 3A28-C nrPDB 72 2e-13 4MOW-A nrPDB 72 3e-13 4AVY-A nrPDB 72 4e-13 3UVE-A nrPDB 71 4e-13 2B4Q-A nrPDB 71 5e-13 3R3S-A nrPDB 70 6e-13 3T7C-A nrPDB 69 1e-12 3ZV3-A nrPDB 69 1e-12 3W8F-A nrPDB 69 1e-12 4DA9-A nrPDB 69 2e-12 5O3Z-A nrPDB 69 2e-12 1X1T-A nrPDB 68 3e-12 4Z9Y-A nrPDB 67 6e-12 5JY1-A nrPDB 67 6e-12 4RGB-A nrPDB 67 8e-12 4IIV-A nrPDB 65 2e-11 4E6P-A nrPDB 65 3e-11 4CR6-A nrPDB 65 3e-11 1H5Q-A nrPDB 65 3e-11 1K2W-A nrPDB 65 3e-11 3UN1-A nrPDB 64 7e-11 5B1Y-A nrPDB 64 7e-11 1BDB-A nrPDB 62 3e-10 1DOH-A nrPDB 62 4e-10 2ZAT-A nrPDB 61 4e-10 3O4R-A nrPDB 61 6e-10 1B15-A nrPDB 60 1e-09 4HP8-A nrPDB 59 2e-09 2FWM-X nrPDB 59 2e-09 1YXM-A nrPDB 59 2e-09 3UF0-A nrPDB 59 3e-09 3OML-A nrPDB 59 3e-09 3RKU-A nrPDB 58 3e-09 6CI9-A nrPDB 58 4e-09 1CYD-A nrPDB 57 1e-08 2X9N-A nrPDB 55 2e-08 1MG5-A nrPDB 55 4e-08 4GKB-A nrPDB 54 5e-08 4HBG-A nrPDB 54 6e-08 3GDF-A nrPDB 53 1e-07 2QHX-A nrPDB 51 4e-07 2BFA-A nrPDB 51 4e-07 2AG5-A nrPDB 51 5e-07 2NWQ-A nrPDB 50 8e-07 3PXX-A nrPDB 50 9e-07 3V8B-A nrPDB 50 1e-06 1P33-A nrPDB 50 1e-06 3D3W-A nrPDB 49 2e-06 3OIC-A nrPDB 48 3e-06 4EGF-A nrPDB 45 3e-05 1O5I-A nrPDB 44 1e-04 3O26-A nrPDB 44 1e-04 1A27-A nrPDB 42 3e-04 4DRY-A nrPDB 42 3e-04 6CGE-A nrPDB 42 4e-04 1FJH-A nrPDB 39 0.002 5LCX-A nrPDB 39 0.002 3KZV-A nrPDB 39 0.003 3E9N-A nrPDB 39 0.003 5L51-A nrPDB 39 0.003 3UCF-A nrPDB 39 0.003 2YW9-A nrPDB 38 0.004 2DKN-A nrPDB 38 0.005 1N5D-A nrPDB 36 0.018 3BHI-A nrPDB 35 0.032 3U4C-A nrPDB 35 0.044 2HRB-A nrPDB 32 0.19 3U9L-A nrPDB 32 0.26 5LV0-A nrPDB 31 0.44 4Z3K-A nrPDB 30 1.0 4FXY-P nrPDB 30 1.0 4HWK-A nrPDB 30 1.4 4LN1-A nrPDB 29 1.6 4EJ6-A nrPDB 28 2.8 2EFY-A nrPDB 28 3.3 3COS-A nrPDB 28 3.6 1W73-A nrPDB 28 4.3 4B1B-A nrPDB 28 4.7 3K4W-A nrPDB 28 5.6 5FDF-A nrPDB 27 7.3 5HFN-A nrPDB 27 7.6 3IP1-A nrPDB 27 8.6 4WOK-A nrPDB 27 9.7 >1E3W-A nrPDB Length = 261 Score = 520 bits (1340), Expect = e-148, Method: Compositional matrix adjust. Identities = 260/261 (99%), Positives = 260/261 (99%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF Sbjct: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV Sbjct: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 PIARDLAPIGIRVVTIAPGLFATPLLTTLPD VRNFLASQVPFPSRLGDPAEYAHLVQMV Sbjct: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 241 IENPFLNGEVIRLDGAIRMQP 261 >2O23-A nrPDB Length = 265 Score = 464 bits (1194), Expect = e-131, Method: Compositional matrix adjust. Identities = 229/261 (87%), Positives = 246/261 (94%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 MAAA RSVKGLVAVITGGASGLGL+TA+RLVGQGA+AVLLD+PNS GE +AKKLG NC+F Sbjct: 3 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 62 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 APA+VTSEK+VQ AL LAK KFGR+DVAVNCAGIAVA KTY+ KK Q HTLEDFQRV++V Sbjct: 63 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 122 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL+GTFNVIRLVAG MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 123 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 182 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 PIARDLAPIGIRV+TIAPGLF TPLLT+LP+KV NFLASQVPFPSRLGDPAEYAHLVQ + Sbjct: 183 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 242 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 243 IENPFLNGEVIRLDGAIRMQP 263 >3PPI-A nrPDB Length = 281 Score = 194 bits (492), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 102/257 (39%), Positives = 155/257 (60%), Gaps = 1/257 (0%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++ +G A+++GGA GLG +T +RL G V+ D+ +G+ A +LG F N Sbjct: 25 IKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTN 84 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VTSE V AA+ A + GR+ AV G + ++ + F + I++ L G Sbjct: 85 VTSEDSVLAAIEAANQ-LGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNG 143 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T+NV RLVA + EP + G+RG ++ TAS+A +EGQ+GQ AY+A+K G++G+T+ AR Sbjct: 144 TYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAAR 203 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP 244 DL+ GIRV TIAPG TP++ ++ ++ A+ +PFP RLG P E+A ++ N Sbjct: 204 DLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFADAAAFLLTNG 263 Query: 245 FLNGEVIRLDGAIRMQP 261 ++NGEV+RLDGA R P Sbjct: 264 YINGEVMRLDGAQRFTP 280 >4NBV-A nrPDB Length = 246 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 91/257 (35%), Positives = 131/257 (50%), Gaps = 18/257 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLGGNCIFAPAN 64 ++G VA+ITG A+G+G +TA+R GA VL DV + E G + Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRVD 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VT EV A + R+D+ VN AGI + + T F VI+VNL G Sbjct: 63 VTRRDEVDAMVAAVLAAHQRVDILVNNAGIT------KDARLAKMTEAQFDAVIDVNLKG 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 FN + VAG+M +QG +GVI+N +SV G GQ Y+ASK G++G T AR Sbjct: 117 VFNCAQAVAGLM----TEQG--KGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWAR 170 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN- 243 +L P G+RV + PG T +L T+PDKV + + S + RL +PAE A + + + Sbjct: 171 ELGPKGVRVNAVCPGFVNTEILQTVPDKVLDGMTSSC-WLRRLAEPAEIASIYAFLASDD 229 Query: 244 -PFLNGEVIRLDGAIRM 259 ++NG I G + + Sbjct: 230 ASYVNGVAIEASGGMSL 246 >2HQ1-A nrPDB Length = 247 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 87/258 (33%), Positives = 135/258 (52%), Gaps = 19/258 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLGGNCIFAPA 63 +KG A++TG + GLG + A +L GA VL P S E K G N + A Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKG 62 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + ++V+ + A + FGRID+ VN AGI T K ++ +D+ V+N NL Sbjct: 63 DVKNPEDVENMVKTAMDAFGRIDILVNNAGITR--DTLMLKMSE----KDWDDVLNTNLK 116 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + V+ +M + + G IIN S+A G GQA Y+ASK G++G T IA Sbjct: 117 SAYLCTKAVSKIMLKQ------KSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIA 170 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI-- 241 ++ A GI +APG+ T + LPDKV+ + +P R G P E A++V + Sbjct: 171 KEFAAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPLK-RFGTPEEVANVVGFLASD 229 Query: 242 ENPFLNGEVIRLDGAIRM 259 ++ ++ G+VI +DG + M Sbjct: 230 DSNYITGQVINIDGGLVM 247 >4JRO-A nrPDB Length = 271 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 88/262 (33%), Positives = 133/262 (50%), Gaps = 25/262 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAP 62 +++G VAV+TGG+ G+G A L +GA + E E KL G Sbjct: 26 TLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAMK 85 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL--EDFQRVINV 120 ANV ++V A A E+FGR+D+ VN AGI + N + + +++ VIN+ Sbjct: 86 ANVAIAEDVDAFFKQAIERFGRVDILVNNAGIT--------RDNLLMRMKEDEWDDVINI 137 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQR-GVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL GTF + V+ M + QR G IIN ASV G GQA Y ASK G++G+T Sbjct: 138 NLKGTFLCTKAVSRTMMK-------QRAGKIINMASVVGLIGNAGQANYVASKAGVIGLT 190 Query: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 AR+LAP GI V +APG T + L +K + + +Q+P + G + A+ V Sbjct: 191 KTTARELAPRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQIPLGA-YGTTEDIANAVLF 249 Query: 240 VIEN--PFLNGEVIRLDGAIRM 259 + + ++ G+ + +DG + M Sbjct: 250 LASDASKYITGQTLSVDGGMVM 271 >4CQL-A nrPDB Length = 261 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 83/265 (31%), Positives = 132/265 (49%), Gaps = 25/265 (9%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----------N 57 ++ +A++TG SG+G + + RL G+GAT D+ + + + LGG N Sbjct: 9 LRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGN 68 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRI-DVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 A+V+ + + L + F R V V+CAGI H + +D+ + Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE------DDWDK 122 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 VI VNL GTF V + A + N G RG IIN +S+ G VGQ Y+ASK G++ Sbjct: 123 VIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNYAASKAGVI 177 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHL 236 G+T AR+L GIR ++ PG ATP+ +P KV + + +P LGDP + A + Sbjct: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVADV 236 Query: 237 VQMVI--ENPFLNGEVIRLDGAIRM 259 V + ++ ++ G + + G + M Sbjct: 237 VAFLASEDSGYITGTSVEVTGGLFM 261 >3RSH-A nrPDB Length = 251 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 134/258 (51%), Gaps = 21/258 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 +++G VA++TG + G+G + A+ L +GA + S + + LG N NVT Sbjct: 9 NLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVT 68 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL--EDFQRVINVNLIG 124 + + ++A L ++FG +D+ VN AGI + N + + E++ ++ NL Sbjct: 69 NPESIEAVLKAITDEFGGVDILVNNAGIT--------RDNLLMRMKEEEWSDIMETNLTS 120 Query: 125 TFNVIRLV-AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F + + V G+M + ++G IIN SV G GQA Y+A+K G++G T +A Sbjct: 121 IFRLSKAVLRGMMKK-------RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMA 173 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI-- 241 R++A G+ V T+APG T + L D+ R +QVP RLGDP E A V + Sbjct: 174 REVASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVP-AGRLGDPREIASAVAFLASP 232 Query: 242 ENPFLNGEVIRLDGAIRM 259 E ++ GE + ++G + M Sbjct: 233 EAAYITGETLHVNGGMYM 250 >4NBT-A nrPDB Length = 240 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 87/262 (33%), Positives = 133/262 (50%), Gaps = 29/262 (11%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAV---LLDVPNSEGETEAKKLGGNCIFA 61 ++ ++G VAVITGGA GLG + A +GA + L D+ S E L Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYL------- 53 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 NVT V+ +K+G+ID+ VN AGI + + T + VI+VN Sbjct: 54 --NVTDVTGVEKFYQSVIDKYGKIDILVNNAGIT------KDAMTRKMTEAQWDAVIDVN 105 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G FN+ RLV M N G IIN +SV G +GQA Y+A+K G++G+T+ Sbjct: 106 LKGVFNLTRLVGPQMQTN------GYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMT 159 Query: 182 IARDLAPIG--IRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 A++ A G +RV IAPG T +L T+P + + A+ + +RLG P E A + Sbjct: 160 WAKEFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAA-LTMLNRLGQPEEIAKVALF 218 Query: 240 VIEN--PFLNGEVIRLDGAIRM 259 + + ++ G+ I ++G +R+ Sbjct: 219 LASDDASYVTGQTINVNGGMRL 240 >4KMS-A nrPDB Length = 249 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 89/265 (33%), Positives = 131/265 (49%), Gaps = 23/265 (8%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG---N 57 MA +A++TGG G+G +TA L +G T V N + E ++ G Sbjct: 1 MAHHHHHHMSEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTK 60 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGR-IDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 C NV +E + A+ +E+F + + + VN AGI K H +Q D+ Sbjct: 61 CW----NVADFEECRQAVKEIEEEFKKPVSILVNNAGI-TKDKMLHRMSHQ-----DWND 110 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 VINVNL FN + + VM Q G+ I+N +S+ A GQVGQ YSA+K GI+ Sbjct: 111 VINVNLNSCFN---MSSSVMEQMRNQDYGR---IVNISSINAQAGQVGQTNYSAAKAGII 164 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHL 236 G T +AR+ A I V IAPG AT ++ +P+ V + + +P RLG P E A Sbjct: 165 GFTKALARETASKNITVNCIAPGYIATEMVGAVPEDVLAKIINSIP-KKRLGQPEEIARA 223 Query: 237 VQMVIENP--FLNGEVIRLDGAIRM 259 V +++ F+ GE I ++G M Sbjct: 224 VAFLVDENAGFITGETISINGGHNM 248 >3WOH-A nrPDB Length = 251 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 86/265 (32%), Positives = 132/265 (49%), Gaps = 33/265 (12%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS----EGETEAKKLGGNCIFAP 62 ++ G VA++TGG+ GLG + A RL GA ++ V + E + E ++LGG Sbjct: 8 ALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYR 67 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGI-----AVAIKTYHEKKNQVHTLEDFQRV 117 +V+ ++V + G +D+ VN AGI A +IK ED+ V Sbjct: 68 CDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKD-----------EDYDAV 116 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVG 177 +N NL G F I+ A G + G IIN +SV+ G GQA Y+++K G++G Sbjct: 117 MNTNLKGAFLFIK--ACYFGFIRK----RSGSIINISSVSGVFGSAGQANYASAKAGLIG 170 Query: 178 MTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFP-SRLGDPAEYAHL 236 +T IA++LA +R +APGL AT + L D + P P R G P E A L Sbjct: 171 LTKSIAKELAERNVRCNAVAPGLIATDMTQDLVDDSKRL----DPVPMRRFGRPDEVAGL 226 Query: 237 VQMVI--ENPFLNGEVIRLDGAIRM 259 V + E+ ++ G+V+ +DG + M Sbjct: 227 VAFLAGDESSYITGQVVCVDGGMAM 251 >1NFF-A nrPDB Length = 260 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 129/253 (50%), Gaps = 26/253 (10%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G VA+++GGA G+G S + +V +GA V D+ + EG+ A +L + +VT Sbjct: 5 LTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVTQ 64 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + +AA+ A FG + V VN AGI + I T + + L ++QR+++VNL G F Sbjct: 65 PAQWKAAVDTAVTAFGGLHVLVNNAGI-LNIGTIED-----YALTEWQRILDVNLTGVFL 118 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 IR V +P + RG IIN +S+ G V Y+A+K + G+T A +L Sbjct: 119 GIRAVV------KPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELG 172 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI-----E 242 P GIRV +I PGL TP+ +P+ + F + LG AE + +V+ E Sbjct: 173 PSGIRVNSIHPGLVKTPMTDWVPEDI---------FQTALGRAAEPVEVSNLVVYLASDE 223 Query: 243 NPFLNGEVIRLDG 255 + + G +DG Sbjct: 224 SSYSTGAEFVVDG 236 >4DMM-A nrPDB Length = 269 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 84/256 (32%), Positives = 131/256 (51%), Gaps = 25/256 (9%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA-----PANVT 66 +A++TG + G+G + A L GA V ++ +S G + A+V+ Sbjct: 30 IALVTGASRGIGRAIALELAAAGAK-VAVNYASSAGAADEVVAAIAAAGGEAFAVKADVS 88 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E EV+A E++GR+DV VN AGI K+ +D+Q V+++NL G F Sbjct: 89 QESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKR------DDWQSVLDLNLGGVF 142 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R A +M + + G IIN ASV G GQA YSA+K G++G+T +A++L Sbjct: 143 LCSRAAAKIMLKQ------RSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKEL 196 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP-- 244 A GI V +APG AT + + L + L +P R G+ AE A +V+ + +P Sbjct: 197 ASRGITVNAVAPGFIATDMTSELAAE---KLLEVIPL-GRYGEAAEVAGVVRFLAADPAA 252 Query: 245 -FLNGEVIRLDGAIRM 259 ++ G+VI +DG + M Sbjct: 253 AYITGQVINIDGGLVM 268 >5CDY-A nrPDB Length = 244 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 78/257 (30%), Positives = 126/257 (49%), Gaps = 19/257 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 S +G +A++TG + G+G + A+ LV +GA + E + LG N NV Sbjct: 2 SFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVV 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLED--FQRVINVNLIG 124 + L + +FG +D+ VN AGI + N + ++D +Q +I+ NL Sbjct: 62 DPTSIDTVLATIRAEFGEVDILVNNAGIT--------RDNLLMRMKDDEWQDIIDTNLTS 113 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + + V M + + G II SV G GQ Y+A+K G++G + +AR Sbjct: 114 VFRLSKAVMRAMMKK------RFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAR 167 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--E 242 ++A GI V +APG T + TL D R + +QVP +RLGD E A V + E Sbjct: 168 EVASRGITVNVVAPGFIETDMTRTLTDDQRAGILAQVP-ANRLGDAKEIASAVAFLASDE 226 Query: 243 NPFLNGEVIRLDGAIRM 259 +++GE + ++G + M Sbjct: 227 ASYISGETLHVNGGMYM 243 >2PNF-A nrPDB Length = 248 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 76/258 (29%), Positives = 125/258 (48%), Gaps = 23/258 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLGGNCIFAPA 63 ++G V+++TG G+G + A++L G+T ++ E A K G Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEM 64 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 N+ SE+ + A ID+ VN AGI +K +L D++ V+ VNL Sbjct: 65 NLLSEESINKAFEEIYNLVDGIDILVNNAGIT------RDKLFLRMSLLDWEEVLKVNLT 118 Query: 124 GTFNVIRLVAGVMGQNEPDQ--GGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 GTF ++ QN + + G I+N +SV F G VGQ YS +K G++G T Sbjct: 119 GTF--------LVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKS 170 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 +A++LAP + V +APG T + L ++++ Q+P R G P E A++V + Sbjct: 171 LAKELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPL-GRFGSPEEVANVVLFLC 229 Query: 242 EN--PFLNGEVIRLDGAI 257 ++ GEVI ++G + Sbjct: 230 SELASYITGEVIHVNGGM 247 >2UVD-A nrPDB Length = 246 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 79/260 (30%), Positives = 132/260 (50%), Gaps = 23/260 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA----KKLGGNCIFAPA 63 +KG VA++TG + G+G + A L QGA V+ N + E KKLG + I A Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL--EDFQRVINVN 121 +V + ++V + + FG++D+ VN AG+ K N + + E++ VIN N Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVT--------KDNLLMRMKEEEWDTVINTN 113 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G F + V+ M + + G I+N ASV G GQA Y A+K G++G+T Sbjct: 114 LKGVFLCTKAVSRFMMRQ------RHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKT 167 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 A++LA I V IAPG AT + L + ++ + +P ++ G+ + A+ V Sbjct: 168 SAKELASRNITVNAIAPGFIATDMTDVLDENIKAEMLKLIP-AAQFGEAQDIANAVTFFA 226 Query: 242 --ENPFLNGEVIRLDGAIRM 259 ++ ++ G+ + +DG + M Sbjct: 227 SDQSKYITGQTLNVDGGMVM 246 >4CQM-B nrPDB Length = 244 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 128/253 (50%), Gaps = 26/253 (10%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-ETEAKKLGGNCIFAPANVTSEKE 70 V + GG+ G+G + A+ + +G ++ N EG + A LGG+ + +V E + Sbjct: 11 VCAVFGGSRGIGRAVAQLMARKGYRLAVI-ARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 69 Query: 71 VQAALTLAKEKFGRIDVAVNCAGI---AVAIKTYHEKK-NQVHTLEDFQRVINVNLIGTF 126 VQ ++ GR++ VN AGI + ++T E +Q+HT NL+G+ Sbjct: 70 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHT----------NLLGSM 119 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++ Sbjct: 120 LTCKAAMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 173 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFL 246 A IRV +APG T + L ++ L +P R G+ E AH V ++E+P++ Sbjct: 174 ARKKIRVNVVAPGFVHTDMTKDLKEE---HLKKNIPL-GRFGETIEVAHAVVFLLESPYI 229 Query: 247 NGEVIRLDGAIRM 259 G V+ +DG +++ Sbjct: 230 TGHVLVVDGGLQL 242 >4RZH-A nrPDB Length = 247 Score = 106 bits (265), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 87/259 (33%), Positives = 128/259 (49%), Gaps = 31/259 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-------GGNCIFAPAN 64 VA++TG + G+G +TA L G V V ++ T A + GG I AN Sbjct: 8 VALVTGASRGIGKATALALAATGMKVV---VNYAQSSTAADAVVAEIIANGGEAIAVQAN 64 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V + EV + +KF RIDV VN AGI K LED+Q VI++NL G Sbjct: 65 VANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMK------LEDWQAVIDLNLTG 118 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + V+ +M + + G IIN SVA G GQA YSA+K G++G T +A+ Sbjct: 119 VFLCTKAVSKLMLKQKS------GRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAK 172 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTL-PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 +LA G+ V +APG AT + L + + F +P +R G P E A ++ + + Sbjct: 173 ELASRGVTVNAVAPGFIATDMTENLNAEPILQF----IPL-ARYGQPEEVAGTIRFLATD 227 Query: 244 P---FLNGEVIRLDGAIRM 259 P ++ G+ +DG + M Sbjct: 228 PAAAYITGQTFNVDGGMVM 246 >3EZL-A nrPDB Length = 256 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 83/254 (32%), Positives = 122/254 (48%), Gaps = 19/254 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS----EGETEAKKLGGNCIFAPANVTS 67 +A +TGG G+G S +RL G V PNS + + K LG + + NV Sbjct: 15 IAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGD 74 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + A K + G IDV VN AGI + + T ED+Q VI+ NL FN Sbjct: 75 WDSTKQAFDKVKAEVGEIDVLVNNAGIT------RDVVFRKMTREDWQAVIDTNLTSLFN 128 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V + V M ++G R IIN +SV +GQ GQ YS +K GI G T+ +A+++A Sbjct: 129 VTKQVIDGM----VERGWGR--IINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVA 182 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPF 245 G+ V T++PG T ++ + V + + +P RLG P E +V + E+ F Sbjct: 183 TKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPV-RRLGSPDEIGSIVAWLASEESGF 241 Query: 246 LNGEVIRLDGAIRM 259 G L+G + M Sbjct: 242 STGADFSLNGGLHM 255 >3VZS-A nrPDB Length = 257 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 81/254 (31%), Positives = 125/254 (49%), Gaps = 19/254 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKK-LGGNCIFAPANVTS 67 +A +TGG G+G + +RL G V PNS E E +K LG + I + NV Sbjct: 16 IAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVAD 75 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + A K + G +DV +N AGI + + + T D+ VI+ NL FN Sbjct: 76 WDSTKTAFDKVKSEVGEVDVLINNAGITRDV-VFRK-----MTRADWDAVIDTNLTSLFN 129 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V + V M D+G R I+N +SV +GQ GQ YS +K G+ G T+ +A+++A Sbjct: 130 VTKQVIDGM----ADRGWGR--IVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVA 183 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPF 245 G+ V T++PG AT ++ + V + + + +P RLG P E A + + E+ F Sbjct: 184 TKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVK-RLGLPEEIASICAWLSSEESGF 242 Query: 246 LNGEVIRLDGAIRM 259 G L+G + M Sbjct: 243 STGADFSLNGGLHM 256 >3OSU-A nrPDB Length = 246 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 130/257 (50%), Gaps = 27/257 (10%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-----KKLGGNCIFAPANVTS 67 A++TG + G+G S A +L +G V ++ S+ + EA K G + ANV Sbjct: 7 ALVTGASRGIGRSIALQLAEEGYN-VAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVAD 65 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL--EDFQRVINVNLIGT 125 EV+A + +FG +DV VN AGI + N + + +++ VI+ NL G Sbjct: 66 ADEVKAMIKEVVSQFGSLDVLVNNAGIT--------RDNLLMRMKEQEWDDVIDTNLKGV 117 Query: 126 FNVIRLVAGVMGQNEPDQGGQR-GVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 FN I+ + P QR G IIN +SV G GQA Y A+K G++G+T AR Sbjct: 118 FNCIQ-------KATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAAR 170 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN- 243 +LA GI V +APG + + L D+++ + +Q+P +R G + A+ V + + Sbjct: 171 ELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPL-ARFGQDTDIANTVAFLASDK 229 Query: 244 -PFLNGEVIRLDGAIRM 259 ++ G+ I ++G + M Sbjct: 230 AKYITGQTIHVNGGMYM 246 >5IZ4-A nrPDB Length = 271 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 80/252 (31%), Positives = 122/252 (48%), Gaps = 19/252 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG------ETEAKKLGGNCIFAPANV 65 V VITG ASG+G +TA R G + + + +S E + G + A+V Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + + + A+ + ++ RID +NCAG I H +Q+ E F+RV VNLIG Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIP--HNAFDQIDDFE-FERVYRVNLIGL 132 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + + R A V E + ++N +S+A G AY+ASKG + +TL +AR+ Sbjct: 133 YQMTR--AAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARN 190 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDK-----VRNFLASQVPFPSRLGDPAEYAHLVQMV 240 LAP IRV +APG+ LL + D V + + P R+ PAE A L + Sbjct: 191 LAP-HIRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPL-KRVSRPAEIAELAWFL 248 Query: 241 IEN-PFLNGEVI 251 + P + G+VI Sbjct: 249 TAHAPAITGQVI 260 >5ITV-A nrPDB Length = 255 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 82/259 (31%), Positives = 126/259 (48%), Gaps = 26/259 (10%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI-FAPANVTSEKEVQ 72 +ITGGASG+G + + +GQ A V+ D+ ++GE +K + + F ++T E Q Sbjct: 11 LITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEAACQ 70 Query: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 A+ A FG +DV +N AGI + + HE + L D+ +V+ VNL G F + + Sbjct: 71 HAVESAVHTFGGLDVLINNAGIEI-VAPIHEME-----LSDWNKVLQVNLTGMFLMSKHA 124 Query: 133 AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 M +G IINT SV AY+ASKGG++ +T +A D A IR Sbjct: 125 LKHM------LAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 178 Query: 193 VVTIAPGLFATPLLT---------TLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 V + PG+ TPL TL ++++ A P RLG P E A+++ + + Sbjct: 179 VNCVCPGIIDTPLNEKSFLENNEGTL-EEIKKEKAKVNPLL-RLGKPEEIANVMLFLASD 236 Query: 244 --PFLNGEVIRLDGAIRMQ 260 ++ G I DG Q Sbjct: 237 LSSYMTGSAITADGGYTAQ 255 >2CFC-A nrPDB Length = 250 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 22/255 (8%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKK----LGGNCIFAPANVTS 67 VA++TG +SG GL+ A R + +G LD+ E A+ + A+V Sbjct: 4 VAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVAD 63 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHT--LEDFQRVINVNLIGT 125 E +V AA+ E+FG IDV VN AGI T + + +HT +E F +V+ VN+ G Sbjct: 64 EGDVNAAIAATMEQFGAIDVLVNNAGI-----TGNSEAGVLHTTPVEQFDKVMAVNVRGI 118 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F R V M QG GVI+N ASVA+ G++AY+ SKG ++ +T +A D Sbjct: 119 FLGCRAVLPHMLL----QGA--GVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVD 172 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDK--VRNFLASQVPFPSRLGDPAEYAHLVQMVI-- 241 A GIR + PG+ TP+ D+ +R+ + +++P +G A+ A V + Sbjct: 173 YAGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIP-QKEIGTAAQVADAVMFLAGE 231 Query: 242 ENPFLNGEVIRLDGA 256 + ++NG + +DGA Sbjct: 232 DATYVNGAALVMDGA 246 >5T5Q-A nrPDB Length = 247 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 121/250 (48%), Gaps = 20/250 (8%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA--PANVTSEKEV 71 V+TG G+G + A+ GA VL D+ + A LG A A+ +S + Sbjct: 13 VLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSADDA 72 Query: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRL 131 + + LA E+FG ID V AGI Y K + D+ R I++NL G F + + Sbjct: 73 EKTVALAMERFGGIDFLVPSAGI------YQAKPFAEMSDADWHRTISINLDGVFYLCKR 126 Query: 132 VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 + ++ I+ AS+AA+ G A Y A+KG +V MT ++R+LAP Sbjct: 127 ALPALKEDSS--------IVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAP-KT 177 Query: 192 RVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNGE 249 RV ++PG+ TP+ + L + +Q P RLG P+E A ++ + F+ GE Sbjct: 178 RVNGVSPGIIETPMTSELLKTRMDETMTQTPL-KRLGKPSEIASVIAFLCSPAASFVTGE 236 Query: 250 VIRLDGAIRM 259 I+++G I M Sbjct: 237 TIQVNGGIYM 246 >2CDH-G nrPDB Length = 244 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 123/254 (48%), Gaps = 22/254 (8%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS-----EGETEAKKLGGNCIFAPANVT 66 V V+TG + G+G + A L G+ VL++ S E + + GG I +V+ Sbjct: 3 VVVVTGASRGIGKAIALSL-GKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVS 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E +V+A + A + +G IDV VN AGI KK+Q + VI++NL G F Sbjct: 62 KEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQ------WDEVIDLNLTGVF 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + +M + ++G IIN ASV G +GQA Y+A+K G++G + AR+ Sbjct: 116 LCTQAATKIMMKK------RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREG 169 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP-- 244 A I V + PG A+ + L + + + +P R G P A LV+ + +P Sbjct: 170 ASRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPL-GRTGQPENVAGLVEFLALSPAA 228 Query: 245 -FLNGEVIRLDGAI 257 ++ G+ +DG I Sbjct: 229 SYITGQAFTIDGGI 242 >2HSD-A nrPDB Length = 253 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 82/258 (31%), Positives = 131/258 (50%), Gaps = 17/258 (6%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + G +ITGGA GLG A++ V GA VL DV + EG A++LG + +VT Sbjct: 2 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVT 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E++ Q + A+E+FG +D VN AGI+ + + ++E F++V+ +NL G F Sbjct: 62 IEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFL------ETESVERFRKVVEINLTGVF 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 ++ V M D GG G I+N +S A G ++Y ASK G+ G++ A +L Sbjct: 116 IGMKTVIPAM----KDAGG--GSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVEL 169 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFP-SRLGDPAEYAHLVQMVIEN-- 243 IRV ++ PG+ TP+ T +R + P R+G+P E A V ++ + Sbjct: 170 GTDRIRVNSVHPGMTYTPM--TAETGIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTS 227 Query: 244 PFLNGEVIRLDGAIRMQP 261 ++ G + +DG P Sbjct: 228 SYVTGAELAVDGGWTTGP 245 >4IS3-A nrPDB Length = 268 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 80/267 (29%), Positives = 129/267 (48%), Gaps = 38/267 (14%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----------EAKKLGGN 57 V+ V +ITGG G+G + AK + GA + E +T E + LG Sbjct: 23 VQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLG-- 80 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL---EDF 114 FAP ++TS V AA+ +K+GR+DV +N AGI N V + E+F Sbjct: 81 --FAP-DLTSRDAVMAAVGQVAQKYGRLDVMINNAGIT---------SNNVFSRVSEEEF 128 Query: 115 QRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174 + ++++N+ G FN G + + ++GVIINTASV G + Y ASK Sbjct: 129 KHIMDINVTGVFN------GAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKAS 182 Query: 175 IVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYA 234 ++G+T + R++ IRVV +APG+ T + P ++ +P R+ +P E A Sbjct: 183 VIGLTHGLGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPM-KRMLEPEEIA 241 Query: 235 HLVQMVIENPFLNG---EVIRLDGAIR 258 + V + + + +G + +DGA R Sbjct: 242 N-VYLFLASDLASGITATTVSVDGAYR 267 >1Q7C-A nrPDB Length = 244 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 124/255 (48%), Gaps = 19/255 (7%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 +G +A++TG + G+G + A+ L +GA + + + + LG N NVT Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDP 63 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLED--FQRVINVNLIGTF 126 +++ L + +FG +D+ VN AGI + N + ++D + +I NL F Sbjct: 64 ASIESVLEKIRAEFGEVDILVNNAGIT--------RDNLLMRMKDEEWNDIIETNLSSVF 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + + G II SV G GQA ++A+K G++G + +AR++ Sbjct: 116 RLSKAVMRAMMKK------RHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREV 169 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENP 244 A GI V +APG T + L D R + +QVP RLG E A+ V + E Sbjct: 170 ASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVP-AGRLGGAQEIANAVAFLASDEAA 228 Query: 245 FLNGEVIRLDGAIRM 259 ++ GE + ++G + M Sbjct: 229 YITGETLHVNGGMYM 243 >4RZI-B nrPDB Length = 240 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 79/251 (31%), Positives = 122/251 (48%), Gaps = 29/251 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 V V+TGG G+G + K L GA D+ G TEA LG ANVT + + Sbjct: 10 VIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA--LG-----VVANVTDLESM 62 Query: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE--DFQRVINVNLIGT-FNV 128 AA +K G + V AGI K N L D+ V+NVNL G +++ Sbjct: 63 TAAAAEITDKLGPVYGVVANAGIT--------KDNFFPKLTPADWDAVLNVNLKGVAYSI 114 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + G+ + + G I+ +S++ G VGQ YSA+K G++GM +AR+ A Sbjct: 115 KPFIEGMYER-------KAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGAR 167 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE---NPF 245 G+R +APG T + + + +R + ++PF R G P E A V ++ + + Sbjct: 168 YGVRANAVAPGFIDTEMTLAIREDIREKITKEIPF-RRFGKPEEIAWAVAFLLSPVASSY 226 Query: 246 LNGEVIRLDGA 256 + GEV+R++GA Sbjct: 227 VTGEVLRVNGA 237 >1GEE-A nrPDB Length = 261 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 84/265 (31%), Positives = 132/265 (49%), Gaps = 22/265 (8%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET-----EAKKLGGNCIF 60 + ++G V VITG ++GLG S A R + A V+++ + E E E KK+GG I Sbjct: 3 KDLEGKVVVITGSSTGLGKSMAIRFATEKAK-VVVNYRSKEDEANSVLEEIKKVGGEAIA 61 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 +VT E +V + A ++FG++DV +N AG+ + + HE +L D+ +VI+ Sbjct: 62 VKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSS-HE-----MSLSDWNKVIDT 115 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 116 NLTGAFLGSREAIKYFVEND-----IKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTE 170 Query: 181 PIARDLAPIGIRVVTIAPGLFATPL-LTTLPD-KVRNFLASQVPFPSRLGDPAEYAHLVQ 238 +A + AP GIRV I PG TP+ D + R + S +P +G+P E A + Sbjct: 171 TLALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPM-GYIGEPEEIAAVAA 229 Query: 239 MVI--ENPFLNGEVIRLDGAIRMQP 261 + E ++ G + DG + + P Sbjct: 230 WLASSEASYVTGITLFADGGMTLYP 254 >4K6F-A nrPDB Length = 255 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 82/256 (32%), Positives = 123/256 (48%), Gaps = 20/256 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIFAPANVTS 67 +AV+TGG GLG + + RL G V+ PN+ G TE G P +V Sbjct: 13 IAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVAD 72 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 Q + G +D+ VN AGI + K ++V ++ VI NL FN Sbjct: 73 HDSCQQCIEKIVRDVGPVDILVNNAGITRDMTL--RKLDKV----NWDAVIRTNLDSVFN 126 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + + V M ++G R I+N +SV +G VGQ Y+A+K G+ G T +A ++A Sbjct: 127 MTKPVCDGM----VERGWGR--IVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIA 180 Query: 188 PIGIRVVTIAPGLFATPLLTTLP-DKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENP 244 G+ V T++PG AT ++T +P D + + Q+P RLG P E A LV + E Sbjct: 181 RKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIP-AGRLGKPEEVAALVAYLCSEEAG 239 Query: 245 FLNGEVIRLDGAIRMQ 260 F+ G I ++G M Sbjct: 240 FVTGSNIAINGGQHMH 255 >3EMK-A nrPDB Length = 246 Score = 97.1 bits (240), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 123/255 (48%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + G A++TG GLG + A+ L QGA L + + A +LG PAN++ Sbjct: 4 DLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLS 63 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + V+A A+E+ G +D+ VN AGI + + ED+ V+ VNL F Sbjct: 64 DREAVKALGQKAEEEMGGVDILVNNAGIT------RDGLFVRMSDEDWDAVLTVNLTSVF 117 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N+ R + P + G IIN S+ G GQA Y ASK G++G + +A+++ Sbjct: 118 NLTREL------THPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEI 171 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENP 244 A + V IAPG + + L +K ++ + +P R+G A+ A V + E Sbjct: 172 ASRNVTVNCIAPGFIESAMTGKLNEKQKDAIMGNIPMK-RMGVGADIAAAVVYLASDEAA 230 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 231 YVTGQTLHVNGGMAM 245 >3U5T-A nrPDB Length = 267 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 86/257 (33%), Positives = 128/257 (49%), Gaps = 30/257 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKK--------LGGNCIFAPA 63 VA++TG + G+G + A RL G T V+ N G+ A + GG + A A Sbjct: 29 VAIVTGASRGIGAAIAARLASDGFTVVI----NYAGKAAAAEEVAGKIEAAGGKALTAQA 84 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V+ V+ A+E FG +DV VN AGI + + T E + V F RVI VNL Sbjct: 85 DVSDPAAVRRLFATAEEAFGGVDVLVNNAGI-MPLTTIAETGDAV-----FDRVIAVNLK 138 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GTFN +R A + + G R + ++T+ V G Y+A+K G+ MT ++ Sbjct: 139 GTFNTLREAAQRL------RVGGRIINMSTSQVGLLHPSYG--IYAAAKAGVEAMTHVLS 190 Query: 184 RDLAPIGIRVVTIAPGLFATPL-LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI- 241 ++L I V +APG AT L L D+VR+ A P RLG P + A V + Sbjct: 191 KELRGRDITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPL-ERLGTPQDIAGAVAFLAG 249 Query: 242 -ENPFLNGEVIRLDGAI 257 + ++NG+V+R +G I Sbjct: 250 PDGAWVNGQVLRANGGI 266 >3AUT-A nrPDB Length = 269 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 83/264 (31%), Positives = 130/264 (49%), Gaps = 22/264 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET-----EAKKLGGNCIFA 61 +K V VITGG++GLG + A R GQ V+++ N+E E E ++ GG I Sbjct: 12 DLKDKVVVITGGSTGLGRAMAVRF-GQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIV 70 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 +VT E++V + A ++FG +DV +N AG+ + + HE +L+++ +VI+ N Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPS-HEL-----SLDNWNKVIDTN 124 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 125 LTGAFLGSREAIKYFVENDI-----KGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTET 179 Query: 182 IARDLAPIGIRVVTIAPGLFATPL-LTTLPDKV-RNFLASQVPFPSRLGDPAEYAHLVQM 239 +A + AP GIRV I PG TP+ D V R + S +P +G P E A + Sbjct: 180 LALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPM-GYIGKPEEVAAVAAF 238 Query: 240 VIEN--PFLNGEVIRLDGAIRMQP 261 + + ++ G + DG + P Sbjct: 239 LASSQASYVTGITLFADGGMTKYP 262 >2C07-A nrPDB Length = 285 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 67/251 (26%), Positives = 121/251 (48%), Gaps = 18/251 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPANVTSE 68 VA++TG G+G AK L + + + ++ E K G +V+ + Sbjct: 46 VALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSKK 105 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +E+ + + +D+ VN AGI + KN ++++ V+ NL F + Sbjct: 106 EEISEVINKILTEHKNVDILVNNAGITRD-NLFLRMKN-----DEWEDVLRTNLNSLFYI 159 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + ++ M N + G IIN +S+ G VGQA YS+SK G++G T +A++LA Sbjct: 160 TQPISKRMINN------RYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELAS 213 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP--FL 246 I V IAPG ++ + + ++++ + S +P R+G P E A+L + + ++ Sbjct: 214 RNITVNAIAPGFISSDMTDKISEQIKKNIISNIP-AGRMGTPEEVANLACFLSSDKSGYI 272 Query: 247 NGEVIRLDGAI 257 NG V +DG + Sbjct: 273 NGRVFVIDGGL 283 >1HXH-A nrPDB Length = 253 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 122/258 (47%), Gaps = 21/258 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 ++G VA++TGGASG+GL K L+G+GA D+ + G+ A +LG +F +V+S Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSS 63 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 E + + + + G ++V VN AGI + + LEDF R++ +N F Sbjct: 64 EADWTLVMAAVQRRLGTLNVLVNNAGILLP------GDMETGRLEDFSRLLKINTESVF- 116 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I G+ E G IIN ASV+++ A YSASK + +T A Sbjct: 117 -IGCQQGIAAMKETG-----GSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCR 170 Query: 188 PIG--IRVVTIAPGLFATPLL-TTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--- 241 G IRV +I P TP++ +LP V + P +R G + Q+V+ Sbjct: 171 KQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLA 230 Query: 242 --ENPFLNGEVIRLDGAI 257 E+ ++G + D +I Sbjct: 231 SDESSVMSGSELHADNSI 248 >1UZM-A nrPDB Length = 247 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 119/248 (47%), Gaps = 23/248 (9%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 ++TGG G+GL+ A+RL G + G K L G + +VT V Sbjct: 19 LVTGGNRGIGLAIAQRLAADGHKVAV----THRGSGAPKGLFGVEV----DVTDSDAVDR 70 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVA 133 A T +E G ++V V+ AG++ T E F++VIN NL G F V + + Sbjct: 71 AFTAVEEHQGPVEVLVSNAGLSADAFLMR------MTEEKFEKVINANLTGAFRVAQRAS 124 Query: 134 GVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRV 193 M +N + G +I SV+ G QA Y+ASK G++GM IAR+L+ + Sbjct: 125 RSMQRN------KFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTA 178 Query: 194 VTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPFLNGEVI 251 +APG T + L ++++ +P R+G PAE A +V + + +++G VI Sbjct: 179 NVVAPGYIDTDMTRALDERIQQGALQFIP-AKRVGTPAEVAGVVSFLASEDASYISGAVI 237 Query: 252 RLDGAIRM 259 +DG + M Sbjct: 238 PVDGGMGM 245 >2NM0-A nrPDB Length = 253 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 118/259 (45%), Gaps = 29/259 (11%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANV 65 RS ++TGG G+GL+ A+ G + GE L C ++ Sbjct: 17 RSHMSRSVLVTGGNRGIGLAIARAFADAGDKVA---ITYRSGEPPEGFLAVKC-----DI 68 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQV---HTLEDFQRVINVNL 122 T ++V+ A +E G ++V + AG+ K+Q+ + EDF V+ NL Sbjct: 69 TDTEQVEQAYKEIEETHGPVEVLIANAGVT---------KDQLLMRMSEEDFTSVVETNL 119 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 GTF V++ M + ++G ++ +SV G GQA Y+ASK G+VG + Sbjct: 120 TGTFRVVKRANRAMLR------AKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSL 173 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 AR+L I +APG T + L D+ R + SQVP R P E A V+ + Sbjct: 174 ARELGSRNITFNVVAPGFVDTDMTKVLTDEQRANIVSQVPL-GRYARPEEIAATVRFLAS 232 Query: 243 N--PFLNGEVIRLDGAIRM 259 + ++ G VI +DG + M Sbjct: 233 DDASYITGAVIPVDGGLGM 251 >3FTP-A nrPDB Length = 270 Score = 91.3 bits (225), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 75/255 (29%), Positives = 119/255 (46%), Gaps = 22/255 (8%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-----KKLGGNCIFAPANVT 66 VA++TG + G+G + A L +GA +++ +E E K+ G A NV Sbjct: 30 VAIVTGASRGIGRAIALELARRGA--MVIGTATTEAGAEGIGAAFKQAGLEGRGAVLNVN 87 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 V A + ++FG ++V VN AGI K +++ VI+ NL F Sbjct: 88 DATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKD------DEWDAVIDTNLKAVF 141 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + R V P + G I+N SV G GQ Y+A+K G+ GMT +AR++ Sbjct: 142 RLSRAVL------RPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREI 195 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENP 244 GI V +APG T + LP + + L +Q+P RLG P + AH V + + Sbjct: 196 GSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPL-GRLGSPEDIAHAVAFLASPQAG 254 Query: 245 FLNGEVIRLDGAIRM 259 ++ G + ++G + M Sbjct: 255 YITGTTLHVNGGMFM 269 >2Q2Q-A nrPDB Length = 255 Score = 90.9 bits (224), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 74/236 (31%), Positives = 113/236 (47%), Gaps = 35/236 (14%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE-----TEAKKLGGNCIFA 61 ++KG A++TG SG+GL A+ L GA VL N G+ E + G + Sbjct: 1 TLKGKTALVTGSTSGIGLGIAQVLARAGANIVL----NGFGDPAPALAEIARHGVKAVHH 56 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 PA+++ +++A LA+ +FG +D+ VN AGI H + LE + ++I +N Sbjct: 57 PADLSDVAQIEALFALAEREFGGVDILVNNAGI------QHVAPVEQFPLESWDKIIALN 110 Query: 122 LIGTFNVIRL-VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 L F+ RL + G+ +N G IIN ASV G G+AAY A+K G+VG+T Sbjct: 111 LSAVFHGTRLALPGMRARN-------WGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTK 163 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLL-TTLPDKVRNFLASQVPFPSRLGDPAEYAH 235 + + A + I PG TPL+ + D+ N GDP + H Sbjct: 164 VVGLETATSNVTCNAICPGWVLTPLVQKQIDDRAANG-----------GDPLQAQH 208 >3V2H-A nrPDB Length = 281 Score = 90.5 bits (223), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 69/216 (31%), Positives = 107/216 (49%), Gaps = 18/216 (8%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVL--LDVPNSEGETEAKKLG---GNCIF 60 +S+ AVITG SG+GL+ A+ L GA VL P+ + G G + Sbjct: 21 QSMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLH 80 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 PA++T E+ + + ++FG D+ VN AG+ +K + +E + R+I V Sbjct: 81 HPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFV------EKIEDFPVEQWDRIIAV 134 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL +F+ IR G P + G IIN AS ++AY A+K GI+G+T Sbjct: 135 NLSSSFHTIR------GAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTK 188 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLL-TTLPDKVRN 215 +A ++A G+ V +I PG TPL+ +PD+ R Sbjct: 189 TVALEVAESGVTVNSICPGYVLTPLVEKQIPDQART 224 >3LYL-A nrPDB Length = 247 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 71/256 (27%), Positives = 124/256 (48%), Gaps = 24/256 (9%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCIFAPANVTSE 68 VA++TG + G+G A L +GAT V + E K+ G N++ Sbjct: 7 VALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNISDI 66 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL--EDFQRVINVNLIGTF 126 + +Q K + ID+ VN AGI + N + + +++Q VIN NL F Sbjct: 67 ESIQNFFAEIKAENLAIDILVNNAGIT--------RDNLMMRMSEDEWQSVINTNLSSIF 118 Query: 127 NVIR-LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + + V G+M + + G II+ SV G GQ Y A+K G++G + +A + Sbjct: 119 RMSKECVRGMMKK-------RWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYE 171 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--EN 243 +A I V +APG AT + L D+ ++F+A+++P ++G+P + A V + E Sbjct: 172 VASRNITVNVVAPGFIATDMTDKLTDEQKSFIATKIP-SGQIGEPKDIAAAVAFLASEEA 230 Query: 244 PFLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 231 KYITGQTLHVNGGMYM 246 >1GEG-A nrPDB Length = 256 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 74/261 (28%), Positives = 123/261 (47%), Gaps = 26/261 (9%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCIFAPANVTSE 68 VA++TG G+G + A RLV G + D ++ + +E + GG+ + +V+ Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSDR 63 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +V AA+ A++ G DV VN AG+A + + T E +V N+N+ G Sbjct: 64 DQVFAAVEQARKTLGGFDVIVNNAGVAPSTPI------ESITPEIVDKVYNINVKGVIWG 117 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 I+ A V + GG+ IIN S A G A YS+SK + G+T ARDLAP Sbjct: 118 IQ--AAVEAFKKEGHGGK---IINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAP 172 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPS----------RLGDPAEYAHLVQ 238 +GI V PG+ TP+ + +V + + + RL +P + A V Sbjct: 173 LGITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVS 232 Query: 239 MVI--ENPFLNGEVIRLDGAI 257 + ++ ++ G+ + +DG + Sbjct: 233 YLASPDSDYMTGQSLLIDGGM 253 >3F9I-A nrPDB Length = 249 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 70/253 (27%), Positives = 122/253 (48%), Gaps = 21/253 (8%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-ETEAKKLGGNCIFAPANVTSE 68 G ++ITG +SG+G + A RL+ + + V++ N E ++ L N N+ ++ Sbjct: 14 GKTSLITGASSGIGSAIA-RLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLANK 72 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +E ++ K +D+ V AGI K +DF +VI++NL F + Sbjct: 73 EECSNLIS----KTSNLDILVCNAGITSDTLAIRMKD------QDFDKVIDINLKANFIL 122 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 R M Q + G IIN +S+ G GQA Y ASK G++GMT ++ ++A Sbjct: 123 NREAIKKMIQK------RYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVAT 176 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--PFL 246 GI V +APG + + L +K R + ++P + G P + A+ V + N ++ Sbjct: 177 RGITVNAVAPGFIKSDMTDKLNEKQREAIVQKIPLGT-YGIPEDVAYAVAFLASNNASYI 235 Query: 247 NGEVIRLDGAIRM 259 G+ + ++G + M Sbjct: 236 TGQTLHVNGGMLM 248 >4IIN-A nrPDB Length = 271 Score = 86.7 bits (213), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 116/257 (45%), Gaps = 29/257 (11%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLGGNCIFAPANVTSEK 69 +ITG + G+G AK L G + N+E + E ++ G + SE Sbjct: 33 LITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASES 92 Query: 70 EVQAALTLAKEKFGRIDVAVNCAGI-----AVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 + A+ + G + VN AG+ A+ +KT EDF VI+ NL Sbjct: 93 DFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKT-----------EDFHHVIDNNLTS 141 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F R VM ++ + G ++N AS+ G +GQ YSASKGG++ M+ A Sbjct: 142 AFIGCREALKVMSKS------RFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAY 195 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN- 243 + A IR ++ PG T + L D+++ +P +RLG E A V ++ + Sbjct: 196 EGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPL-NRLGSAKEVAEAVAFLLSDH 254 Query: 244 -PFLNGEVIRLDGAIRM 259 ++ GE ++++G + M Sbjct: 255 SSYITGETLKVNGGLYM 271 >5JS6-A nrPDB Length = 274 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 69/231 (29%), Positives = 114/231 (49%), Gaps = 27/231 (11%) Query: 28 KRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDV 87 + V GA V+ D S G ++L G +F +VT E +V+ ++ +FGR+D Sbjct: 29 RAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVTQEDDVKTLVSETIRRFGRLDC 87 Query: 88 AVNCAGIAVAIKTYHE--KKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGG 145 VN AG +H ++ + + + F++++ +NL+GT+ + +L + +++ Sbjct: 88 VVNNAG-------HHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ----- 135 Query: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205 G +IN +S+ GQ Y A+KG + MT +A D +P G+RV I+PG TPL Sbjct: 136 --GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPL 193 Query: 206 LTTL----PD---KVRNFLASQVPFPSRLGDPAEY-AHLVQMVIENPFLNG 248 L PD +R + +Q P R+G PAE A V + E F G Sbjct: 194 WEELAALMPDPRATIREGMLAQ-PL-GRMGQPAEVGAAAVFLASEANFCTG 242 >3WTC-A nrPDB Length = 262 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 62/223 (27%), Positives = 108/223 (48%), Gaps = 24/223 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN---SEGETEAKKLGGNCIFAPA 63 S+ G +A +TG A G+G + A RL GA +LLDV +E E + LG + A Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTA 64 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ-----RVI 118 ++++ + ++ L A + G +D+ VN AGI QV + D + ++ Sbjct: 65 DISNRDQFRSTLADAAKTLGGLDIMVNNAGIC-----------QVKPILDIEPAEIEKIF 113 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 ++N+ G ++ A + + G +G IIN S+A EG AYSA+K + + Sbjct: 114 SINVQGVLWGMQAAATLFKEK-----GTKGKIINACSIAGHEGYPLLGAYSATKFAVRAL 168 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV 221 T A++LA GI V + PG+ T + T+ ++ +++ Sbjct: 169 TQSAAKELASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEI 211 >5VT6-A nrPDB Length = 269 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 119/257 (46%), Gaps = 22/257 (8%) Query: 12 VAVITGGASGLGLSTAKRLVGQG-ATAVLLDVPNSEGET---EAKKLGGNCIFAPANVTS 67 VA +TGG GLG + ++RL G A AV N T + G + +V Sbjct: 27 VAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVAD 86 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + + FG++DV +N AGI + T D+ V+ +L FN Sbjct: 87 FESCERCAEKVLADFGKVDVLINNAGIT------RDATFMKMTKGDWDAVMRTDLDAMFN 140 Query: 128 VIR-LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 V + +AG++ + + G I+N SV G GQA Y+++K GI G T +A + Sbjct: 141 VTKQFIAGMVER-------RFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALET 193 Query: 187 APIGIRVVTIAPGLFATPLLTTLP-DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP- 244 A GI V T++PG AT ++ +P D + + Q+P RLG P E A L+ + + Sbjct: 194 AKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPV-GRLGRPDEVAALIAFLCSDDA 252 Query: 245 -FLNGEVIRLDGAIRMQ 260 F+ G + ++G + M Sbjct: 253 GFVTGADLAINGGMHMS 269 >5ILO-A nrPDB Length = 271 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 66/213 (30%), Positives = 105/213 (49%), Gaps = 23/213 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAV-LLDVPNSEGE---TEAKKLGGNCIFAP 62 S +G AV+TGGA G+GL +K+L+ GA V ++D+ ++ E A + + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V ++K V+A + FG ID+ VN AGI +++K D QR + VNL Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGI------FNDK--------DVQRTLLVNL 117 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G N MG+ D GG+ G+++N +SV + Y A+K GI+ T + Sbjct: 118 GGIINSTLSALPYMGK---DNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCL 174 Query: 183 ARD--LAPIGIRVVTIAPGLFATPLLTTLPDKV 213 A + GI+ VT+ PG T + T +K+ Sbjct: 175 ANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKI 207 >4BO1-A nrPDB Length = 269 Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 74/260 (28%), Positives = 122/260 (46%), Gaps = 22/260 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA--- 63 S++G VA++TG + G+G + A L GA + S E A+ L N + Sbjct: 24 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL 83 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLED--FQRVINVN 121 +V+S++ V A L ++ G+ + VN AGI + N + ++D + V+N N Sbjct: 84 DVSSDESVAATLEHIQQHLGQPLIVVNNAGIT--------RDNLLVRMKDDEWFDVVNTN 135 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L + + + V M + + G IIN SV G GQ Y+A+K G+ G T Sbjct: 136 LNSLYRLSKAVLRGMTK------ARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRA 189 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 +AR++ I V +APG T + LP+ R L Q+P RLG E A +V + Sbjct: 190 LAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPL-GRLGQAEEIAKVVGFLA 248 Query: 242 EN--PFLNGEVIRLDGAIRM 259 + ++ G + ++G + M Sbjct: 249 SDGAAYVTGATVPVNGGMYM 268 >3RWB-A nrPDB Length = 247 Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 115/252 (45%), Gaps = 14/252 (5%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEK 69 G A++TG A G+G + A RL GAT ++ D+ + A +G A+++ Sbjct: 6 GKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPG 65 Query: 70 EVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 V+A + G ID+ VN A I V + + L+ ++++I+VNL GTF V Sbjct: 66 SVKALFAEIQALTGGIDILVNNASI-VPFVAWDDVD-----LDHWRKIIDVNLTGTFIVT 119 Query: 130 RLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI 189 R G ++ G+ G +I+ AS F G AAY A+KGG++G T +A +L Sbjct: 120 R-----AGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKY 174 Query: 190 GIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP--FLN 247 I + PGL + + P + G P A +V + + ++ Sbjct: 175 NITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARWIT 234 Query: 248 GEVIRLD-GAIR 258 G+ + +D G +R Sbjct: 235 GQTLNVDAGMVR 246 >5OJG-A nrPDB Length = 260 Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 78/268 (29%), Positives = 130/268 (48%), Gaps = 21/268 (7%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVL--LDVPNSEGETEAKKLGGNC 58 M + R +G VA++T G+GL+ A+RL+ +GA+ V+ + N + E K G Sbjct: 1 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLT 60 Query: 59 IFA--PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 A ++ S + + + +KFG+I++ VN GI A E +QV + + Sbjct: 61 KVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQV-----WDK 115 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 + VN+ F + +LV + + +GG G II AS +A++ G AAY +K +V Sbjct: 116 LFEVNVKAGFQMTKLVHPHIAK----EGG--GAIIFNASYSAYKSPPGIAAYGVTKTTLV 169 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTL----PDKVRNFLASQVPFPSRLGDPAE 232 G+T +A LA IRV IAPG+ T + L D + Q RLG P + Sbjct: 170 GLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDD 229 Query: 233 YAHLVQMVI--ENPFLNGEVIRLDGAIR 258 A V + ++ ++ GE+I + G ++ Sbjct: 230 CAGTVAYLASDDSSYITGEMIIIAGGVQ 257 >2PH3-A nrPDB Length = 245 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 115/252 (45%), Gaps = 20/252 (7%) Query: 13 AVITGGASGLGLSTAKRLVGQG-ATAVLL--DVPNSEGETEAKKLGGNCIFA--PANVTS 67 A+ITG + G+G + A RL G A A+ + +E E + G+ + A AN+ Sbjct: 4 ALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANLLE 63 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + A + A E G +D VN AGI K ED++ V+ NL F Sbjct: 64 AEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKD------EDWEAVLEANLSAVFR 117 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 R +M + + G I+N SV G GQA Y ASK G++G T +A++ A Sbjct: 118 TTREAVKLMMK------ARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYA 171 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP--F 245 GI V +APG T + LP +V+ Q+P R G P E A V ++ + Sbjct: 172 QRGITVNAVAPGFIETEMTERLPQEVKEAYLKQIP-AGRFGRPEEVAEAVAFLVSEKAGY 230 Query: 246 LNGEVIRLDGAI 257 + G+ + +DG + Sbjct: 231 ITGQTLCVDGGL 242 >3V2G-A nrPDB Length = 271 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 76/258 (29%), Positives = 120/258 (46%), Gaps = 27/258 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIFAP 62 S+ G A +TGG+ G+G + AKRL +GA L V +E +E ++ GG + Sbjct: 28 SLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIR 87 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 A+ + ++ A+ E G +D+ VN AGI +H + T+ DF V+ VN Sbjct: 88 ADNRDAEAIEQAIRETVEALGGLDILVNSAGI------WHSAPLEETTVADFDEVMAVNF 141 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F IR + +G GG+ +I +++A G + YSASK + G+T + Sbjct: 142 RAPFVAIRSASRHLGD-----GGR--IITIGSNLAELVPWPGISLYSASKAALAGLTKGL 194 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKV---RNFLASQVPFPSRLGDPAEYAHLVQM 239 ARDL P GI V + PG T + D R +A+ G+P + A LV Sbjct: 195 ARDLGPRGITVNIVHPGSTDTDMNPADGDHAEAQRERIAT-----GSYGEPQDIAGLVAW 249 Query: 240 VI--ENPFLNGEVIRLDG 255 + + F+ G + +DG Sbjct: 250 LAGPQGKFVTGASLTIDG 267 >2GDZ-A nrPDB Length = 267 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 43/266 (16%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG---------ETEAKKLGGNC 58 V G VA++TG A G+G + A+ L+ +GA L+D G + E +K Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQK----T 60 Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 +F +V +++++ + FGR+D+ VN AG V+ +++++ + Sbjct: 61 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG--------------VNNEKNWEKTL 106 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 +NL+ + L M + GG+ G+IIN +S+A Q Y ASK GIVG Sbjct: 107 QINLVSVISGTYLGLDYMSKQ---NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGF 163 Query: 179 TLP--IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHL 236 T +A +L G+R+ I PG T +L ++ +K N + + + + D +Y + Sbjct: 164 TRSAALAANLMNSGVRLNAICPGFVNTAILESI-EKEEN-MGQYIEYKDHIKDMIKYYGI 221 Query: 237 VQ---------MVIENPFLNGEVIRL 253 + +IE+ LNG ++++ Sbjct: 222 LDPPLIANGLITLIEDDALNGAIMKI 247 >5U9P-A nrPDB Length = 265 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 24/259 (9%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL---GGNCIFAPAN 64 + G A+ITG G+GL+ A+ L GA V+ D + T A++ G A + Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVFD 77 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE--DFQRVINVNL 122 V +V+AA+ + + G ID+ VN AGI +++ + E D+ ++ VNL Sbjct: 78 VAEHAQVRAAIDEFEARVGAIDILVNNAGI--------QRRAPLDAFEPDDWHALMRVNL 129 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G FNV + VA M G IIN SV + + A Y+A+KG + +T + Sbjct: 130 DGVFNVAQAVARHMIAR------GHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGM 183 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDK--VRNFLASQVPFPSRLGDPAEY--AHLVQ 238 D A GI+ +APG F T L L D ++L + P R G E A + Sbjct: 184 CADWARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTP-AGRWGQVDELCGAAIFL 242 Query: 239 MVIENPFLNGEVIRLDGAI 257 + F+NG+ + +DG + Sbjct: 243 ASAASDFVNGQTLFVDGGL 261 >5YSS-A nrPDB Length = 256 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 64/212 (30%), Positives = 103/212 (48%), Gaps = 23/212 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKK-----LGGNCIFA 61 ++ G A++TG SG+GL A+ L GAT +L N G+ +A K G + Sbjct: 2 NLTGKTALVTGSTSGIGLGIAQVLAQAGATLIL----NGFGDVDAAKDAVAQYGKTPGYH 57 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 A+++ E ++ + A+ +FG +D+ +N AGI H + ++ + +I +N Sbjct: 58 GADLSDEAQIADMMRYAESEFGGVDILINNAGI------QHVSPIETFPVDKWNAIIAIN 111 Query: 122 LIGTFNVIRL-VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 L F+ RL + G+ +N G IIN ASV ++AY A+K G+VG+T Sbjct: 112 LSSVFHTTRLALPGMRARN-------WGRIINIASVHGLVASKEKSAYVAAKHGVVGLTK 164 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDK 212 IA + A I + PG TPL+ DK Sbjct: 165 TIALETAQTEITCNALCPGWVLTPLVQQQIDK 196 >4M8S-A nrPDB Length = 248 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 69/262 (26%), Positives = 121/262 (46%), Gaps = 22/262 (8%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL---GGNCIF 60 + + + G +A++TG + G+G + A L GA + S +++L GG Sbjct: 2 STQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEG-- 59 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 N + V+ + ++ FG++D+ VN AGI K+ E++ ++ V Sbjct: 60 RVLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKE------EEWDDIMQV 113 Query: 121 NLIGTFNVIRLV-AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL F + V G+M Q + G IIN SV G GQ Y+A+K G++G + Sbjct: 114 NLKSVFRASKAVLRGMMKQ-------RAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFS 166 Query: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 +AR++ GI V +APG T + LP++ R +Q R GD + A V Sbjct: 167 KSMAREVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTAL-GRFGDAQDIADAVLF 225 Query: 240 VIEN--PFLNGEVIRLDGAIRM 259 + + ++ G+ + ++G + M Sbjct: 226 LASDQAKYITGQTLHVNGGMLM 247 >3GRP-A nrPDB Length = 266 Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 65/254 (25%), Positives = 118/254 (46%), Gaps = 15/254 (5%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G A++TG G+G + A+ QGA L + + A LG + AN++ Sbjct: 25 LTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSD 84 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 K ++ +A+ + ID+ VN AGI + ++Q D+ V+ VNL Sbjct: 85 RKSIKQLAEVAEREMEGIDILVNNAGITRD-GLFVRMQDQ-----DWDDVLAVNLTAAST 138 Query: 128 VIR-LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + R L+ +M + + G IIN S+ G GQ Y A+K G++G + +A+++ Sbjct: 139 LTRELIHSMMRR-------RYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEI 191 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSR-LGDPAEYAHLVQMVIENPF 245 A I V IAPG + + L +K + + + +P +G+ +A + E + Sbjct: 192 ASRNITVNCIAPGFIKSAMTDKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAY 251 Query: 246 LNGEVIRLDGAIRM 259 L G+ + ++G + M Sbjct: 252 LTGQTLHINGGMAM 265 >3OEC-A nrPDB Length = 317 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 115/247 (46%), Gaps = 33/247 (13%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV----PN---SEGETEAKK-- 53 A + ++G VA ITG A G G + A RL GA V +D+ PN ++G E K Sbjct: 39 ARMNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKET 98 Query: 54 ------LGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQ 107 G I A+V +QA + A +FG ID+ V+ GI+ + + Sbjct: 99 VRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGIS--------NQGE 150 Query: 108 VHTLED--FQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQ 165 V +L D + ++ NLIG ++ R V M + GQ G +I +S G GQ Sbjct: 151 VVSLTDQQWSDILQTNLIGAWHACRAVLPSMIER-----GQGGSVIFVSSTVGLRGAPGQ 205 Query: 166 AAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPS 225 + Y+ASK G+ G+ L +A ++ IRV ++ PG T + L +K+ + P+ Sbjct: 206 SHYAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVNTEM--ALNEKLLKMFLPHLENPT 263 Query: 226 RLGDPAE 232 R D AE Sbjct: 264 R-EDAAE 269 >1AE1-A nrPDB Length = 273 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 126/264 (47%), Gaps = 31/264 (11%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-----AKKLGGNCIFA 61 S+KG A++TGG+ G+G + + L G GA + +E E + ++ G N + Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGAR--VYTCSRNEKELDECLEIWREKGLNVEGS 75 Query: 62 PANVTSEKEVQAALTLAKEKF-GRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 ++ S E + F G++++ VN AG+ + K+ + T +D+ ++ Sbjct: 76 VCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVI------HKEAKDFTEKDYNIIMGT 129 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 N +++ ++ ++ + Q G +I +S+A F + YSASKG I MT Sbjct: 130 NFEAAYHLSQIAYPLL------KASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTK 183 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTL-------PDKVRNFLASQVPFPSRLGDPAEY 233 +A + A IRV ++APG+ TPL+ T +++ NF+ + P R G P E Sbjct: 184 SLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIV-KTPM-GRAGKPQEV 241 Query: 234 AHLVQMVI--ENPFLNGEVIRLDG 255 + L+ + ++ G++I DG Sbjct: 242 SALIAFLCFPAASYITGQIIWADG 265 >5OVJ-A nrPDB Length = 256 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 111/249 (44%), Gaps = 25/249 (10%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG-NCIFAPANVTSEKEVQ 72 ++TGG G+GL+ A+RL G + G L G C +VT V Sbjct: 28 LVTGGNRGIGLAIARRLAADGHKVAV----THRGSGAPDDLFGVQC-----DVTDSAAVD 78 Query: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 A +E G ++V V AGI+ + T E F+ VIN NL G F + Sbjct: 79 RAFKEVEEHQGPVEVLVANAGIS------KDAFLMRMTEERFEEVINTNLTGAFRCAQRA 132 Query: 133 AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 + M Q + G II SV+ G QA Y+A+K G++GM I+R+LA G+ Sbjct: 133 SRTM------QRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVT 186 Query: 193 VVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPFLNGEV 250 +APG T + L ++++ +P R+G E A V + + ++ G V Sbjct: 187 ANVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAGAV 245 Query: 251 IRLDGAIRM 259 I +DG + M Sbjct: 246 IPVDGGMGM 254 >5OVL-A nrPDB Length = 300 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 111/249 (44%), Gaps = 25/249 (10%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG-NCIFAPANVTSEKEVQ 72 ++TGG G+GL+ A+RL G + G L G C +VT V Sbjct: 72 LVTGGNRGIGLAIARRLAADGHKVAV----THRGSGAPDDLFGVQC-----DVTDSAAVD 122 Query: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 A +E G ++V V AGI+ + T E F+ VIN NL G F + Sbjct: 123 RAFKEVEEHQGPVEVLVANAGIS------KDAFLMRMTEERFEEVINTNLTGAFRCAQRA 176 Query: 133 AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 + M Q + G II SV+ G QA Y+A+K G++GM I+R+LA G+ Sbjct: 177 SRTM------QRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVT 230 Query: 193 VVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPFLNGEV 250 +APG T + L ++++ +P R+G E A V + + ++ G V Sbjct: 231 ANVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAGAV 289 Query: 251 IRLDGAIRM 259 I +DG + M Sbjct: 290 IPVDGGMGM 298 >4FC7-A nrPDB Length = 277 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 76/254 (29%), Positives = 117/254 (46%), Gaps = 24/254 (9%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----NCIFAPANVTS 67 VA ITGG SG+G A+ + G V+ T A+KL G C+ +V + Sbjct: 29 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 88 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 V AA+ A ++FGRID+ +NCA + F+ V++++ GTFN Sbjct: 89 PPAVMAAVDQALKEFGRIDILINCAAGNFLCPA------GALSFNAFKTVMDIDTSGTFN 142 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V R++ + D GG VI+N + GQ Q ++K + MT +A + Sbjct: 143 VSRVLYEKFFR---DHGG---VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 196 Query: 188 PIGIRVVTIAPG-LFATPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP 244 P IRV ++APG + T L L P + + P RLG+ E AH V + + +P Sbjct: 197 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSV-LYLASP 254 Query: 245 ---FLNGEVIRLDG 255 ++ G V+ DG Sbjct: 255 LASYVTGAVLVADG 268 >4DBZ-A nrPDB Length = 281 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 111/245 (45%), Gaps = 27/245 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-ETEAKKLGGNCIFAP---ANVTS 67 VA++TG SG+GL A+RL G+ V + EG T K+L + A +V S Sbjct: 28 VALVTGATSGIGLEIARRL-GKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRS 86 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 E++A + E++G +DV VN AG T E + V+ NL G F Sbjct: 87 VPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELAD------ELWLDVVETNLTGVFR 140 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V + V G E G I+N AS +G V A YSASK G+VG T + +LA Sbjct: 141 VTKQVLKAGGMLERGTG----RIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELA 196 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNF-----------LASQVPFPSRLGDPAEYAHL 236 GI V + PG TP+ ++ + + + ++VP R P+E A + Sbjct: 197 RTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPI-GRYVQPSEVAEM 255 Query: 237 VQMVI 241 V +I Sbjct: 256 VAYLI 260 >2BGM-A nrPDB Length = 278 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 55/186 (29%), Positives = 96/186 (51%), Gaps = 17/186 (9%) Query: 27 AKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI--FAPANVTSEKEVQAALTLAKEKFGR 84 AK V GA V+ D+ + G+ +G + F +VT +++V+ + K G+ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 85 IDVAVNCAGIAVAIKTYH--EKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPD 142 +D+ G+ ++ Y E N EDF+RV+++N+ G F V + A VM Sbjct: 93 LDIMFGNVGV-LSTTPYSILEAGN-----EDFKRVMDINVYGAFLVAKHAARVM------ 140 Query: 143 QGGQRGVIINTASVAAFEGQVG-QAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLF 201 ++G I+ TAS+++F G Y+A+K ++G+T + +L GIRV ++P + Sbjct: 141 IPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIV 200 Query: 202 ATPLLT 207 A+PLLT Sbjct: 201 ASPLLT 206 >5EJ2-A nrPDB Length = 308 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/254 (27%), Positives = 119/254 (46%), Gaps = 35/254 (13%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV---------PNSEGETEA------K 52 V G VA I+G A G G S A RL +GA + +D+ P+S E A K Sbjct: 35 VAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVK 94 Query: 53 KLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE 112 L + A +V + +++A+ E+ GR+D+ V AG+ + H+ ++ V Sbjct: 95 DLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNV---- 150 Query: 113 DFQRVINVNLIGTFNVIRLVAGVMGQNEPD--QGGQRGVIINTASVAAFEGQVGQAAYSA 170 +Q +I++NL G ++ ++ AGV P GG+ G I+ T+SV + Y A Sbjct: 151 -WQDMIDINLTGVWHTVK--AGV-----PHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIA 202 Query: 171 SKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDP 230 +K G++G+ A +L P IRV + P +T ++ + D+ + P P Sbjct: 203 AKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMV--MNDQTFRLFRPDLENPG----P 256 Query: 231 AEYAHLVQMVIENP 244 ++A + QM+ P Sbjct: 257 DDFAPISQMMHTLP 270 >2AE2-A nrPDB Length = 260 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 65/262 (24%), Positives = 127/262 (48%), Gaps = 24/262 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCIFAPA 63 +++G A++TGG+ G+G + L GA+ E T+ + G + Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVC 65 Query: 64 NVTSEKEVQAAL-TLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +++S E Q + T+A G++++ VN AGI + Y E K+ +T+ED+ ++++N Sbjct: 66 DLSSRSERQELMNTVANHFHGKLNILVNNAGIVI----YKEAKD--YTVEDYSLIMSINF 119 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +++ L + + +RG ++ +SV+ +A Y A+KG + +T + Sbjct: 120 EAAYHLSVLAHPFL------KASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCL 173 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTL---PDKVRNF--LASQVPFPSRLGDPAEYAHLV 237 A + A IRV + PG+ AT L+ P++ N L + R+G+P E A +V Sbjct: 174 AFEWAKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCAL-RRMGEPKELAAMV 232 Query: 238 QMVI--ENPFLNGEVIRLDGAI 257 + ++ G++I +DG + Sbjct: 233 AFLCFPAASYVTGQIIYVDGGL 254 >3WYE-A nrPDB Length = 256 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 74/262 (28%), Positives = 125/262 (47%), Gaps = 28/262 (10%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCIFAPANVTSE 68 VA++TG G+G + A RLV G + D ++ + +E + GG+ + +V+ Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSDR 63 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +V AA+ A++ G DV VN AGIA IK E T ED +++ +VN+ F Sbjct: 64 DQVFAAVEQARKTLGGFDVIVNNAGIA-QIKPLLEV-----TEEDLKQIYSVNVFSVFFG 117 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 I+ A V + GG+ + A++ F +AYS +K + G+T ARDLAP Sbjct: 118 IQ--AAVEAFKKEGHGGKIINAASIAAIQGFPIL---SAYSTTKFAVRGLTQTAARDLAP 172 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKV---------RNF--LASQVPFPSRLGDPAEYAHLV 237 +GI V PG+ T + + ++ NF +S + R P + A LV Sbjct: 173 LGITVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIAL-GRPSVPEDVAGLV 231 Query: 238 QMVI--ENPFLNGEVIRLDGAI 257 + ++ ++ G+ + +DG + Sbjct: 232 SFLASPDSDYMTGQSLLIDGGM 253 >6NRP-A nrPDB Length = 263 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 120/250 (48%), Gaps = 21/250 (8%) Query: 14 VITGGASGLGLSTAKRLVGQG-ATAVLLDVPNSEGET---EAKKLGGNCIFAPANVTSEK 69 ++TG + G+G + A +L G V +E E E + LG N + +V + Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVNERQ 87 Query: 70 EVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 VQ L E+ G V AG+ H+ T +D+ VI+ +L G +NV+ Sbjct: 88 TVQQILEQDVEQHGGFYGVVLNAGLT------HDGAFPALTDQDWDEVISTSLDGFYNVL 141 Query: 130 RLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI 189 + + +M +GG+ I+ +SV+ G GQ YSA+K G++G T +A +LA Sbjct: 142 KPL--IMPMIHLRKGGR---IVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKR 196 Query: 190 GIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPFLN 247 I V +APGL T ++T D+V+ +P R+G E A +V+ + E ++ Sbjct: 197 KITVNCVAPGLIETEMVT---DEVKEHALKMIPL-QRMGQVDEVASVVKFLCSDEASYVT 252 Query: 248 GEVIRLDGAI 257 +VI ++G + Sbjct: 253 RQVISVNGGL 262 >2EW8-A nrPDB Length = 249 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 73/260 (28%), Positives = 116/260 (44%), Gaps = 24/260 (9%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLD-VPNSEGETEAKKLGGNCIFAPAN 64 + +K +AVITGGA+G+G + A+R +GA + D VP E E + LG + + Sbjct: 3 QRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCD 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V+ +V+A FGR D+ VN AGI I + E T E +++ +N+ Sbjct: 63 VSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIP-FDE-----LTFEQWKKTFEINVDS 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + + M +N G IIN S + Y ++K +G T +A Sbjct: 117 GFLMAKAFVPGMKRN------GWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALAS 170 Query: 185 DLAPIGIRVVTIAPGLFATPL-----LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 DL GI V IAP L T L+ + D + N L + +P RL P + Sbjct: 171 DLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQA-IP---RLQVPLDLTGAAAF 226 Query: 240 VIEN--PFLNGEVIRLDGAI 257 + + F+ G+ + +DG + Sbjct: 227 LASDDASFITGQTLAVDGGM 246 >4TRR-A nrPDB Length = 269 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/223 (27%), Positives = 110/223 (49%), Gaps = 21/223 (9%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIF 60 + ++ G AV+TG ASG+G A L GA + D+ N +G E K GG I Sbjct: 9 MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADL-NQDGANAVADEINKAGGKAIG 67 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVA--IKTYHEKKNQVHTLEDFQRVI 118 +VT+E+ V + E FG +D+ V+ AGI + I+ Y + D++++ Sbjct: 68 VAMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENY--------SFADWKKMQ 119 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 +++ G F + A + + D+GG V+I SV + E ++AY +K G++G+ Sbjct: 120 AIHVDGAFLTTK--AALKHMYKDDRGG---VVIYMGSVHSHEASPLKSAYVTAKHGLLGL 174 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTT-LPDKVRNFLASQ 220 +A++ A +R + PG TPL+ +P++ + S+ Sbjct: 175 ARVLAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISE 217 >1AHH-A nrPDB Length = 255 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 125/256 (48%), Gaps = 24/256 (9%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAPA 63 + G A+ITG +G+G A GA+ V+ D+ N++ E ++LGG Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 ++TSE+E+ A A K G++D+ VN AG K + + DF+R +N+ Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFD------MPMADFRRAYELNVF 120 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F++ +LVA M +N GG GVI+ S+AA + +Y++SK + +A Sbjct: 121 SFFHLSQLVAPEMEKN----GG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 Query: 184 RDLAPIGIRVVTIAPGLFATPLL-TTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 DL IRV IAPG T L + + ++ + P RLG P + A+ + + Sbjct: 175 FDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI-RRLGQPQDIAN-AALFLC 232 Query: 243 NP---FLNGEVIRLDG 255 +P +++G+++ + G Sbjct: 233 SPAASWVSGQILTVSG 248 >3A28-C nrPDB Length = 258 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 83/264 (31%), Positives = 130/264 (49%), Gaps = 30/264 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE-TEAKKL----GGNCIFAPANVT 66 VA++TGGA G+G +++L G + D+P E + E KL +F +VT Sbjct: 4 VAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDVT 63 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + +A+ A EK G DV VN AGIA IK E T ED +++ +VN+ F Sbjct: 64 DKANFDSAIDEAAEKLGGFDVLVNNAGIA-QIKPLLE-----VTEEDLKQIYSVNVFSVF 117 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 I+ + + D+ G +G IIN AS+AA +G +AYS +K + G+T A++L Sbjct: 118 FGIQAAS-----RKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQEL 172 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKV---------RNF--LASQVPFPSRLGDPAEYAH 235 AP G V APG+ T + + ++ NF +S + R P + A Sbjct: 173 APKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIAL-GRPSVPEDVAG 231 Query: 236 LVQMVI-ENP-FLNGEVIRLDGAI 257 LV + EN ++ G+V+ +DG + Sbjct: 232 LVSFLASENSNYVTGQVMLVDGGM 255 >4MOW-A nrPDB Length = 256 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 68/258 (26%), Positives = 118/258 (45%), Gaps = 26/258 (10%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-----KKLGGNCIFAPAN 64 G VA++TG + G+G + AK L +GA AV+++ +S+ +A + GG + + Sbjct: 14 GKVAIVTGASKGIGAAIAKALADEGA-AVVVNYASSKAGADAVVSAITEAGGRAVAVGGD 72 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V+ + Q + A E +GR+DV VN +G+ Y + T E ++R + N+ G Sbjct: 73 VSKAADAQRIVDTAIETYGRLDVLVNNSGV------YEFAPIEAITEEHYRRQFDTNVFG 126 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + Q G+ IIN +SV A YS +KG + +T +A Sbjct: 127 VL--------LTTQAAVKHLGEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLAL 178 Query: 185 DLAPIGIRVVTIAPGLFATPLLTT---LPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 +L P IRV I PG+ T + + + + Q P RLG+P + A + + Sbjct: 179 ELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPL-GRLGEPNDIASVAVFLA 237 Query: 242 ENP--FLNGEVIRLDGAI 257 + ++ GE + + G + Sbjct: 238 SDDARWMTGEHLVVSGGL 255 >4AVY-A nrPDB Length = 242 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 112/255 (43%), Gaps = 45/255 (17%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA---------N 64 ++TGG+SG+G + A + GA V L L + + AP + Sbjct: 15 LVTGGSSGIGAAIAMQFAELGAEVVAL------------GLDADGVHAPRHPRIRREELD 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 +T + +Q E R+DV VN AGI+ + + + L F+RV+ +NL Sbjct: 63 ITDSQRLQRLF----EALPRLDVLVNNAGIS--------RDREEYDLATFERVLRLNLSA 110 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 +L ++ Q + G I+N AS+ + G + AYSASKG IV +T +A Sbjct: 111 AMLASQLARPLLAQ-------RGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLAC 163 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVR--NFLASQVPFPSRLGDPAEYAHLVQMVI- 241 + A IRV IAPG TPL L V + + P +R G+ E A + Sbjct: 164 EYAAERIRVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPL-ARWGEAPEVASAAAFLCG 222 Query: 242 -ENPFLNGEVIRLDG 255 F+ G V+ +DG Sbjct: 223 PGASFVTGAVLAVDG 237 >3UVE-A nrPDB Length = 286 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 101/220 (45%), Gaps = 33/220 (15%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV-----------------PNSEGETE 50 V+G VA +TG A G G S A RL +GA + +D+ P ET Sbjct: 9 VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA 68 Query: 51 AKKLGGN--CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQV 108 G N + A +V ++AA+ E+ GR+D+ V AGI T +K ++ Sbjct: 69 DLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTL-DKTSE- 126 Query: 109 HTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQ--GGQRGVIINTASVAAFEGQVGQA 166 ED+ +I++NL G + ++ AGV P GG+ G II T+SV + Sbjct: 127 ---EDWTEMIDINLAGVWKTVK--AGV-----PHMIAGGRGGSIILTSSVGGLKAYPHTG 176 Query: 167 AYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLL 206 Y A+K G+VG+ +L IRV ++ P TP+L Sbjct: 177 HYVAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPML 216 >2B4Q-A nrPDB Length = 276 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 120/261 (45%), Gaps = 18/261 (6%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG--GNCIFAPAN 64 S+ G +A++TGG+ G+G A+ L+ GA + A +L G+C PA+ Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 85 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIA--VAIKTYHEKKNQVHTLEDFQRVINVNL 122 ++SE + E R+D+ VN AG + A+++Y + +++V+ +N+ Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESY--------PVSGWEKVMQLNV 137 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-AYSASKGGIVGMTLP 181 F+ I+ + ++ ++ + R +IN SVA QA AY SK + ++ Sbjct: 138 TSVFSCIQQLLPLLRRSASAENPAR--VINIGSVAGISAMGEQAYAYGPSKAALHQLSRM 195 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFP-SRLGDPAEYAHLVQMV 240 +A++L I V IAPG F + + + + + A P R G P E A L + Sbjct: 196 LAKELVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISL 255 Query: 241 --IENPFLNGEVIRLDGAIRM 259 ++ G VI +DG + Sbjct: 256 AGTAGAYMTGNVIPIDGGFHL 276 >3R3S-A nrPDB Length = 294 Score = 70.5 bits (171), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 68/255 (26%), Positives = 116/255 (45%), Gaps = 29/255 (11%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-----KKLGGNCIFAP 62 +K A++TGG SG+G + A +GA + +P E + + ++ G + P Sbjct: 47 LKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLLP 106 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +++ E ++ + A+E G +D+ AG AI E K+ T E FQ+ VN+ Sbjct: 107 GDLSDESFARSLVHKAREALGGLDILALVAGKQTAIP---EIKDL--TSEQFQQTFAVNV 161 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F + + ++ + II T+S+ A++ Y+A+K I+ + + Sbjct: 162 FALFWITQEAIPLLPKG--------ASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGL 213 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTT---LPDKVRNFLASQVPFPSRLGDPAE----YAH 235 A+ +A GIRV +APG T L + DK+ F Q P R G PAE Y + Sbjct: 214 AKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQF-GQQTPM-KRAGQPAELAPVYVY 271 Query: 236 LVQMVIENPFLNGEV 250 L E+ ++ EV Sbjct: 272 LASQ--ESSYVTAEV 284 >3T7C-A nrPDB Length = 299 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/219 (30%), Positives = 99/219 (45%), Gaps = 27/219 (12%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV-------------PNSEGET--EAK 52 V+G VA ITG A G G S A L +GA + +DV P+ ET + + Sbjct: 26 VEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVE 85 Query: 53 KLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE 112 LG I + +V +QAA+ + GR+D+ + A A+A + + T Sbjct: 86 ALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVL--ANAALASEGTRLNRMDPKTWR 143 Query: 113 DFQRVINVNLIGTFNVIRL-VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS 171 D I+VNL G + R+ + +M G + G I+ T+S+ G Y AS Sbjct: 144 DM---IDVNLNGAWITARVAIPHIMA------GKRGGSIVFTSSIGGLRGAENIGNYIAS 194 Query: 172 KGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLP 210 K G+ G+ +A +L P IRV + P ATP+L P Sbjct: 195 KHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEP 233 >3ZV3-A nrPDB Length = 281 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 62/201 (30%), Positives = 92/201 (45%), Gaps = 15/201 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G VA+ITGGASGLG + R V +GA +LD GGN + +V S Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVRS 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGI---AVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 ++ + A FG+ID + AGI + A+ E K F + +VN+ G Sbjct: 63 LQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAA----FDDIFHVNVKG 118 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + ++ P RG ++ T S A F G Y+A+K +VG+ +A Sbjct: 119 YIHAVKACL-------PALVSSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAF 171 Query: 185 DLAPIGIRVVTIAPGLFATPL 205 +LAP +RV +APG T L Sbjct: 172 ELAP-HVRVNGVAPGGMNTDL 191 >3W8F-A nrPDB Length = 260 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 63/204 (30%), Positives = 93/204 (45%), Gaps = 17/204 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVL--LDVPNS---EGETEAKKLGGNCIFAP 62 +KG AV+TG SG+GL+ A L GA V+ P E T K G + Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 A+++ + + + A E G +D+ VN AGI H + ++ + +I +NL Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGI------QHTAPIEEFPVDKWNAIIALNL 115 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F+ +M + QG R IIN AS V ++AY A+K G+VG+T Sbjct: 116 SAVFHGTAAALPIMQK----QGWGR--IINIASAHGLVASVNKSAYVAAKHGVVGLTKVT 169 Query: 183 ARDLAPIGIRVVTIAPGLFATPLL 206 A + A GI I PG TPL+ Sbjct: 170 ALENAGKGITCNAICPGWVRTPLV 193 >4DA9-A nrPDB Length = 280 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 116/255 (45%), Gaps = 15/255 (5%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAPANVTS 67 VA++TGG G+GL A+ L G + + ++EG E LG IF A++ Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKT-YHEKKNQVHTLEDFQRVINVNLIGTF 126 QA + +FGRID VN AGIA ++ + + K E+F ++ VNL GT Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKP-----ENFDTIVGVNLRGTV 145 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + V M + D R IIN SV+A + Y SK G+ + +A L Sbjct: 146 FFTQAVLKAMLAS--DARASRS-IINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRL 202 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENP 244 A GI V + PG+ + + + K + S + R G+P + ++V + + Sbjct: 203 AETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLVPMRRWGEPEDIGNIVAGLAGGQFG 262 Query: 245 FLNGEVIRLDGAIRM 259 F G VI+ DG + + Sbjct: 263 FATGSVIQADGGLSI 277 >5O3Z-A nrPDB Length = 263 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 28/229 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-----GGNCIFAPANVT 66 VAV+ GG LG + L G + D+ S A + G + T Sbjct: 8 VAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDAT 67 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E V+A E FGR D+ V AG+A A + L DF + VNL+G F Sbjct: 68 DEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFR------LTDFDLSLQVNLVGYF 121 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R + +M ++ G +G II S + G + YSA+K G VG+T +A DL Sbjct: 122 LCSREFSKLMIRD-----GIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDL 176 Query: 187 APIGIRVVTIAPG-LFATPLLTTL-----------PDKVRNFLASQVPF 223 A GI V ++ G L +P+ +L P++V + +VP Sbjct: 177 AEYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPL 225 >1X1T-A nrPDB Length = 260 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 75/249 (30%), Positives = 109/249 (43%), Gaps = 36/249 (14%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE------AKKLGGNCIFA 61 +KG VAV+TG SG+GL A L QGA VL ++ E E A + G ++ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDA-AEIEKVRAGLAAQHGVKVLYD 60 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 A+++ + V+ + A + GRID+ VN AGI H + E + ++ +N Sbjct: 61 GADLSKGEAVRGLVDNAVRQMGRIDILVNNAGI------QHTALIEDFPTEKWDAILALN 114 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L F+ M QG R IIN AS ++AY A+K G+VG T Sbjct: 115 LSAVFHGTAAALPHM----KKQGFGR--IINIASAHGLVASANKSAYVAAKHGVVGFTKV 168 Query: 182 IARDLAPIGIRVVTIAPGLFATPL----LTTLPDK--------VRNFLASQVP-----FP 224 A + A GI I PG TPL ++ L +K R L+ + P P Sbjct: 169 TALETAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTP 228 Query: 225 SRLGDPAEY 233 +LG A + Sbjct: 229 EQLGGTAVF 237 >4Z9Y-A nrPDB Length = 253 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 71/255 (27%), Positives = 124/255 (48%), Gaps = 19/255 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-AKKLGGNCIFAPANV 65 ++G VA+ITG +GLG A L G V +++ + E LG + A++ Sbjct: 7 DLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADM 66 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE-DFQRVINVNLIG 124 ++ + A +FG +D+ VN AGI +++ + E ++ V+N+N+ Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGII-------RREDAIEFSEKNWDDVMNLNIKS 119 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + + VA + + G+ G IIN AS+ +F+G + +Y+ASK ++G+T +A Sbjct: 120 VFFMSQTVA-----RQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMAN 174 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTL-PDKVRNF-LASQVPFPSRLGDPAEYA--HLVQMV 240 + A GI V IAPG AT L D+ R+ + ++P R G P + + Sbjct: 175 EWAKHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIP-AGRWGLPQDLMGPSVFLAS 233 Query: 241 IENPFLNGEVIRLDG 255 + ++NG I +DG Sbjct: 234 SASDYINGYTIAVDG 248 >5JY1-A nrPDB Length = 274 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 61/236 (25%), Positives = 105/236 (44%), Gaps = 22/236 (9%) Query: 33 QGATAVLLDVPNSEG---ETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAV 89 +GA ++ ++ S G E E +++GG +F +VTS+ ++AA+ A E+FG +D+ V Sbjct: 37 EGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTDVTSKASIEAAVRSAVEQFGSLDILV 96 Query: 90 NCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 N A + EK +++ ++ + +L T+ +R M + + G Sbjct: 97 NNAFVPTPNVLLEEKTDEM-----LEQTLTTSLWATWWAMRAAFVPMRER------RWGR 145 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTL 209 I+N S+ G Y+ +K GIVG+T A + I V IAP L Sbjct: 146 IVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNAIAPTAMGATFF-EL 204 Query: 210 PDKVRNFL---ASQVPFPSRLGDPAEY---AHLVQMVIENPFLNGEVIRLDGAIRM 259 K F A+ P R GDP + A + + F+ GE + +DG + + Sbjct: 205 AAKNPEFAERSAAARPL-GRSGDPEQDIGPAAVFFASEMSRFVTGETLHVDGGLHL 259 >4RGB-A nrPDB Length = 294 Score = 67.0 bits (162), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 75/285 (26%), Positives = 125/285 (43%), Gaps = 44/285 (15%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLD-------VPNSEGETE--------A 51 S+ G V ITG A G G S A QGA V +D VP G E Sbjct: 22 SLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLV 81 Query: 52 KKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL 111 +K G +F A+V + +Q E+FG ID + AG+ + ++ Sbjct: 82 EKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLT------NPDERDAS 135 Query: 112 EDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAF----EGQVGQAA 167 E + +++ LIG +N ++ M + GQ G +I T+S+ A +G+ G A Sbjct: 136 EALRLGLDIMLIGVWNTFQVAIPHMKER-----GQGGNLIATSSMIALLDLTDGRGGTDA 190 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVR---------NFLA 218 Y SK I G+ A LA IRV +AP +TP++T P + N ++ Sbjct: 191 YLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMS 250 Query: 219 SQVP-FPSRLGDPAEYAHLVQMVIENP--FLNGEVIRLDGAIRMQ 260 + +P FP + +P + ++ + +I + G V+++D + ++ Sbjct: 251 TALPDFP--MIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVK 293 >4IIV-A nrPDB Length = 267 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 116/250 (46%), Gaps = 19/250 (7%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPANVTSEK 69 ++TG + G+G + A++L G + ++ G E GGN +V + + Sbjct: 30 LVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVANRE 89 Query: 70 EVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 + + L + G V+ AGIA + + +D+ VI+ NL +NVI Sbjct: 90 QCREVLEHEIAQHGAWYGVVSNAGIA------RDAAFPALSNDDWDAVIHTNLDSFYNVI 143 Query: 130 RLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI 189 + +M QGG+ II +SV+ G GQ YSA+K GI+G T +A +LA Sbjct: 144 QPC--IMPMIGARQGGR---IITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKR 198 Query: 190 GIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--PFLN 247 I V IAPGL T ++ ++ + S +P R+G E A L ++ + ++ Sbjct: 199 KITVNCIAPGLIDTGMIEMEESALKEAM-SMIPMK-RMGQAEEVAGLASYLMSDIAGYVT 256 Query: 248 GEVIRLDGAI 257 +VI ++G + Sbjct: 257 RQVISINGGM 266 >4E6P-A nrPDB Length = 259 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 11/196 (5%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++ ++G A+ITG A G+G + A+ V +GAT + D+ A ++G + Sbjct: 3 MKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMD 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VT + + AA+ E G +D+ VN A + + T E ++++ +N+ G Sbjct: 63 VTRQDSIDAAIAATVEHAGGLDILVNNAAL------FDLAPIVEITRESYEKLFAINVAG 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T ++ A M G+ G IIN AS A G+ A Y A+K ++ +T Sbjct: 117 TLFTLQAAARQMIAQ-----GRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGL 171 Query: 185 DLAPIGIRVVTIAPGL 200 DL I V IAPG+ Sbjct: 172 DLIKHRINVNAIAPGV 187 >4CR6-A nrPDB Length = 271 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 115/255 (45%), Gaps = 14/255 (5%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G A++TG A G+G +T + + +GA+ V +D+ T ++ G I ++ Sbjct: 13 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG--AIPIACDLAD 70 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + AA+ A + G +D+ V + + + + D+ R ++VN+ GTF Sbjct: 71 RAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDA-----DWDRYVDVNMTGTFL 125 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 R A M + G+ II SV +F + AAY A+KGG+ +T +A DLA Sbjct: 126 TCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLA 185 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPA---EYAHLVQMVIEN- 243 GI V IAPG T + R LA QV LG P E A + E+ Sbjct: 186 RHGILVNMIAPGPVDVTGNNTGYSEPR--LAEQVLDEVALGRPGLPEEVATAAVFLAEDG 243 Query: 244 -PFLNGEVIRLDGAI 257 F+ G I +DG + Sbjct: 244 SSFITGSTITIDGGL 258 >1H5Q-A nrPDB Length = 265 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 13/130 (10%) Query: 110 TLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAA-------FEGQ 162 T EDF V +VN+ G FN R VA + Q + Q+G I+ T+S+++ G Sbjct: 112 THEDFAFVYDVNVFGVFNTCRAVAKLWLQKQ-----QKGSIVVTSSMSSQIINQSSLNGS 166 Query: 163 VGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVP 222 + Q Y++SK + +A + A GIRV ++PG T + K+R+ AS +P Sbjct: 167 LTQVFYNSSKAACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIP 226 Query: 223 FPSRLGDPAE 232 +R P E Sbjct: 227 L-NRFAQPEE 235 >1K2W-A nrPDB Length = 256 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 54/193 (27%), Positives = 89/193 (46%), Gaps = 11/193 (5%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G A+ITG A G+G + A+ V +GA + D+ A ++G +VT Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVTD 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + + + +++G ID+ VN A + + T E + R+ +N+ GT Sbjct: 63 QASIDRCVAELLDRWGSIDILVNNAAL------FDLAPIVEITRESYDRLFAINVSGTLF 116 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 +++ VA M GG+ G IIN AS A G+ Y A+K ++ +T +L Sbjct: 117 MMQAVARAM-----IAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLI 171 Query: 188 PIGIRVVTIAPGL 200 GI V IAPG+ Sbjct: 172 RHGINVNAIAPGV 184 >3UN1-A nrPDB Length = 260 Score = 63.9 bits (154), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 14/176 (7%) Query: 80 EKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQN 139 E+FGRID VN AG+ +A K + E T ED+ + VN+ G F++ + A M + Sbjct: 92 ERFGRIDSLVNNAGVFLA-KPFVEM-----TQEDYDHNLGVNVAGFFHITQRAAAEMLK- 144 Query: 140 EPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPG 199 QG V I T+ V + A S +KGG+ +T +A + + G+RV ++PG Sbjct: 145 ---QGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNAVSPG 201 Query: 200 LFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDG 255 + TP+ P + + LA P R+G+ + V + F+ GE++ +DG Sbjct: 202 VIKTPM---HPAETHSTLAGLHPV-GRMGEIRDVVDAVLYLEHAGFITGEILHVDG 253 >5B1Y-A nrPDB Length = 270 Score = 63.9 bits (154), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 62/220 (28%), Positives = 104/220 (47%), Gaps = 22/220 (10%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLL-----DVPNSEGETEAKKLGG-NCIFAPANVT 66 A++TGG+ G+G +T R +G + V+ D+ E EA++LG +V Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAE-EARRLGSPEAYTVRVDVG 84 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 V + E ++V VN AG+ + + E ++ +++ + VNL G + Sbjct: 85 DPDSVTEMSSRVGELIPHLNVLVNAAGV-LQLGGIEET-----SISEWEETLRVNLTGVY 138 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQV-GQAAYSASKGGIVGMTLPIARD 185 V +L+ ++ + + I+N AS+A G V AYSASK G++G+T +A Sbjct: 139 LVTKLLLPLL------RKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQ 192 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPF 223 LA GIRV +AP T + + D + R +AS P Sbjct: 193 LAGYGIRVNAVAPSFVETDMTRSFLDTPEKRERIASLHPL 232 >1BDB-A nrPDB Length = 277 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 15/195 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 +KG +ITGGASGLG + R V +GA +LD G N + +V S Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRS 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGI---AVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 ++ + A + +FG+ID + AGI + A+ E+ F V ++N+ G Sbjct: 63 LEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAA----FDEVFHINVKG 118 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + ++ P RG +I T S A F G Y+A+K IVG+ +A Sbjct: 119 YIHAVKACL-------PALVASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAF 171 Query: 185 DLAPIGIRVVTIAPG 199 +LAP +RV + G Sbjct: 172 ELAPY-VRVNGVGSG 185 >1DOH-A nrPDB Length = 283 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 71/272 (26%), Positives = 118/272 (43%), Gaps = 33/272 (12%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-----KKLGGNCIFA 61 S++G VA++TG G+G A L G+ V+++ NS E KK G + Sbjct: 26 SLEGKVALVTGAGRGIGREMAMEL-GRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACV 84 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 ANV +++ A + FG++D+ + +G+ ++ K+ T E+F RV +N Sbjct: 85 KANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVV----SFGHVKDV--TPEEFDRVFTIN 138 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 G F V R + GG+ +I+ + + A YS SKG I Sbjct: 139 TRGQFFVAR-----EAYKHLEIGGR--LILMGSITGQAKAVPKHAVYSGSKGAIETFARC 191 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLP------------DKVRNFLASQVPFPSRLGD 229 +A D+A I V +APG T + + ++V + A Q R+G Sbjct: 192 MAIDMADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGL 251 Query: 230 PAEYAHLVQMVIENP--FLNGEVIRLDGAIRM 259 P + A +V + N ++ G+VI +DG M Sbjct: 252 PIDIARVVCFLASNDGGWVTGKVIGIDGGACM 283 >2ZAT-A nrPDB Length = 260 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 17/250 (6%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT---SE 68 VA++T G+GL+ A+RL GA V+ + L G + V Sbjct: 16 VALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKA 75 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 ++ + + +A G +D+ V+ A + + +V + ++++VN+ T + Sbjct: 76 EDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEV-----WDKILHVNVKATVLM 130 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + V M + +GG G ++ +SV A+ Y+ SK ++G+T +A +LAP Sbjct: 131 TKAVVPEMEK----RGG--GSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAP 184 Query: 189 IGIRVVTIAPGLFATPLLTTLP-DKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPF 245 IRV +APGL T L DK R + RLG+P + A +V + + + Sbjct: 185 RNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASY 244 Query: 246 LNGEVIRLDG 255 + GE + + G Sbjct: 245 ITGETVVVGG 254 >3O4R-A nrPDB Length = 261 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 25/254 (9%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS---- 67 VA++T G+G + A+RL GA V+ + L G + V Sbjct: 17 VALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKA 76 Query: 68 ---EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 E+ V A+ L G ID+ V+ A + + + +V + + +++N+ Sbjct: 77 EDRERLVATAVKL----HGGIDILVSNAAVNPFFGSIMDVTEEV-----WDKTLDINVKA 127 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + + V M + +GG G ++ +S+AAF G + Y+ SK ++G+T +A Sbjct: 128 PALMTKAVVPEMEK----RGG--GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 181 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLP-DKVRNFLASQVPFPSRLGDPAEYAHLVQMVI-- 241 +LAP IRV +APGL T L DK + + RLG+P + A +V + Sbjct: 182 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 241 Query: 242 ENPFLNGEVIRLDG 255 + ++ GE + + G Sbjct: 242 DASYITGETVVVGG 255 >1B15-A nrPDB Length = 254 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 59/197 (29%), Positives = 87/197 (44%), Gaps = 28/197 (14%) Query: 21 GLGLSTAKRLVGQG-ATAVLLDV---PNSEGETEAKKLGGNCIFAPANVTSE-KEVQAAL 75 G+GL T++ LV + V+LD P + E +A N F +VT E + L Sbjct: 16 GIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHTYDVTVPVAESKKLL 75 Query: 76 TLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ--RVINVNLIGTFNVIRLVA 133 ++ +D+ +N AGI L+D Q R I +N G N Sbjct: 76 KKIFDQLKTVDILINGAGI----------------LDDHQIERTIAINFTGLVNT---TT 116 Query: 134 GVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-GIR 192 ++ + +GG G+I N SV F YSASK +V T +A+ LAPI G+ Sbjct: 117 AILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK-LAPITGVT 175 Query: 193 VVTIAPGLFATPLLTTL 209 +I PG+ TPL+ T Sbjct: 176 AYSINPGITRTPLVHTF 192 >4HP8-A nrPDB Length = 247 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 118/258 (45%), Gaps = 30/258 (11%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLL--DVPNSEGETEAKKLGGNCIFAPAN 64 S++G A++TG +GLG + A L GA V P+ + AK GGN A A Sbjct: 6 SLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKD-GGN---ASAL 61 Query: 65 VTSEKEVQAALTLAKEKF--GRIDVAVNCAGIAVAIKTYHEKKNQVHTLE-DFQRVINVN 121 + + AA K+ F D+ VN AGI + + V E D+ V++VN Sbjct: 62 LIDFADPLAA----KDSFTDAGFDILVNNAGII-------RRADSVEFSELDWDEVMDVN 110 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L F + A E G+ G ++N AS+ +F+G + +Y+A+K G+ G+T Sbjct: 111 LKALFFTTQAFA-----KELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKL 165 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTL-PDKVRN-FLASQVPFPSRLGDPAEYAHLVQM 239 +A + A GI V IAPG T L D RN + ++P R G + A Sbjct: 166 LANEWAAKGINVNAIAPGYIETNNTEALRADAARNKAILERIP-AGRWGHSEDIAGAAVF 224 Query: 240 VIE--NPFLNGEVIRLDG 255 + +++G ++ +DG Sbjct: 225 LSSAAADYVHGAILNVDG 242 >2FWM-X nrPDB Length = 250 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 85/195 (43%), Gaps = 19/195 (9%) Query: 15 ITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA 74 +TG G+G +TA V GA D + T+ + + A+ +V Sbjct: 12 VTGAGKGIGYATALAFVEAGAKVTGFD----QAFTQEQYPFATEVMDVADAAQVAQVCQR 67 Query: 75 LTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAG 134 L E R+D VN AGI T K ED+Q+ VN+ G FN+ + Sbjct: 68 LLAETE---RLDALVNAAGILRMGATDQLSK------EDWQQTFAVNVGGAFNLFQQT-- 116 Query: 135 VMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVV 194 M Q +GG I+ AS AA ++G +AY ASK + + L + +LA G+R Sbjct: 117 -MNQFRRQRGG---AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 172 Query: 195 TIAPGLFATPLLTTL 209 ++PG T + TL Sbjct: 173 VVSPGSTDTDMQRTL 187 >1YXM-A nrPDB Length = 303 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/262 (24%), Positives = 116/262 (44%), Gaps = 28/262 (10%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN--------CI 59 ++G VA++TGGA+G+G + K L+ G+ V+ ++ A +L N I Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 N+ +E+EV + + FG+I+ VN G H H V+ Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHA------VLE 129 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL GTF + + V + + GG II + A F V A++ G+ +T Sbjct: 130 TNLTGTFYMCKAVYSSWMK---EHGGSIVNII-VPTKAGFPLAVHSG---AARAGVYNLT 182 Query: 180 LPIARDLAPIGIRVVTIAPG-LFATPLLTTLPDKVRNFLA---SQVPFPSRLGDPAEYAH 235 +A + A GIR+ +APG +++ + ++F ++P R+G P E + Sbjct: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEVSS 241 Query: 236 LVQMVIE--NPFLNGEVIRLDG 255 +V ++ F+ G+ + +DG Sbjct: 242 VVCFLLSPAASFITGQSVDVDG 263 >3UF0-A nrPDB Length = 273 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 71/256 (27%), Positives = 119/256 (46%), Gaps = 22/256 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-AKKLGGNCIFAPANV 65 S+ G AV+TG SG+G + A GA +L ++G E A ++ A A V Sbjct: 28 SLAGRTAVVTGAGSGIGRAIAHGYARAGAH--VLAWGRTDGVKEVADEIADGGGSAEAVV 85 Query: 66 TSEKEVQAALTLAKEKFG--RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +++ A +A+E R+DV VN AGI +A E +L ++ V+ VNL Sbjct: 86 ADLADLEGAANVAEELAATRRVDVLVNNAGI-IARAPAEEV-----SLGRWREVLTVNLD 139 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + R M + G I+ AS+ +F+G AAY+ASK +VG+T +A Sbjct: 140 AAWVLSRSFGTAMLAHGS------GRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALA 193 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 + A G+ V +APG T L D+ + +++P R P + + Sbjct: 194 SEWAGRGVGVNALAPGYVVTANTAALRADDERAAEITARIP-AGRWATPEDMVGPAVFLA 252 Query: 242 EN--PFLNGEVIRLDG 255 + +++G+V+ +DG Sbjct: 253 SDAASYVHGQVLAVDG 268 >3OML-A nrPDB Length = 613 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 64/228 (28%), Positives = 102/228 (44%), Gaps = 29/228 (12%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDV---PNSEGET---------EAKKLGGN 57 G VAV+TG +GLG A +GA V+ D+ + +G + E +K GG Sbjct: 19 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGE 78 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE-DFQR 116 + A+ S + + A + FGR+D+ VN AGI ++ V T E D+ Sbjct: 79 AV---ADYNSVIDGAKVIETAIKAFGRVDILVNNAGIL-------RDRSLVKTSEQDWNL 128 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 V +V+L G+F + M + G II T+S + G GQ Y+A+K G++ Sbjct: 129 VNDVHLKGSFKCTQAAFPYMKKQ------NYGRIIMTSSNSGIYGNFGQVNYTAAKMGLI 182 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFP 224 G+ +A + A + I P + LPD + N L ++ P Sbjct: 183 GLANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAP 230 >3RKU-A nrPDB Length = 287 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 20/211 (9%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLV--GQGATAVLLDVPNSEGETEAKKL------ 54 AA R K V +ITG ++G+G +TA + G ++L E E KK Sbjct: 27 AAERLAKKTV-LITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFP 85 Query: 55 GGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDF 114 A ++T ++++ + ++F ID+ VN AG A+ ++ Q+ T ED Sbjct: 86 NAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALG----SDRVGQIAT-EDI 140 Query: 115 QRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174 Q V + N+ N+ + V + Q G I+N S+A + + Y ASK Sbjct: 141 QDVFDTNVTALINITQAVLPIF------QAKNSGDIVNLGSIAGRDAYPTGSIYCASKFA 194 Query: 175 IVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205 + T + ++L IRV+ IAPGL T Sbjct: 195 VGAFTDSLRKELINTKIRVILIAPGLVETEF 225 >6CI9-A nrPDB Length = 259 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 59/254 (23%), Positives = 108/254 (42%), Gaps = 17/254 (6%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN---CIFAPA 63 S++G A++TGG+ G+G A+ G V+ + + L G A Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRA 65 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +VT ++ + + + G +D+ AGI + + + T +D ++V+ VN Sbjct: 66 DVTDPEDARRTVAETVSRHGGLDIVCANAGI------FPSGRLEDLTPDDIEQVLGVNFK 119 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GT +++ + + G V++ ++ G G + Y ASK +G A Sbjct: 120 GTVYIVQAALQALTAS-----GHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAA 174 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEY--AHLVQMVI 241 +LAP I + + PG T L + + +AS +P RLG A+ A L Sbjct: 175 MELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIP-AGRLGSVADIGNAALFFATD 233 Query: 242 ENPFLNGEVIRLDG 255 E ++ G+ + +DG Sbjct: 234 EAAYVTGQTLVVDG 247 >1CYD-A nrPDB Length = 244 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 63/207 (30%), Positives = 95/207 (45%), Gaps = 26/207 (12%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG---NCIFAPANVT 66 GL A++TG G+G T K L GA V + NS+ + AK+ G C+ Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDA 66 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 +EK + G +D+ VN A + V ++ + E T E F R +VNL F Sbjct: 67 TEKALGG--------IGPVDLLVNNAAL-VIMQPFLEV-----TKEAFDRSFSVNLRSVF 112 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 V ++VA M G G I+N +S+ A YS++KG + +T +A +L Sbjct: 113 QVSQMVARDMINR-----GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMEL 167 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKV 213 P IRV ++ P T +LT + KV Sbjct: 168 GPHKIRVNSVNP----TVVLTDMGKKV 190 >2X9N-A nrPDB Length = 288 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 61/262 (23%), Positives = 110/262 (41%), Gaps = 17/262 (6%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-----AKKLGGNCIFAPANVTS 67 AV+TG A +G + A +L G V+ ++E K+ + A++T+ Sbjct: 26 AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTN 85 Query: 68 EKEVQAA----LTLAKEKFGRIDVAVNCAGIAVA---IKTYHEKKNQVHTLE-DFQRVIN 119 + A+ + FGR DV VN A ++ HE + T+E +I Sbjct: 86 SNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG 145 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 N I F + A P+ I+N + + + Y+ K +VG+T Sbjct: 146 TNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLT 205 Query: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 A +LAP GIRV +APG+ P+ + ++ ++ +VP R + A V Sbjct: 206 QSAALELAPYGIRVNGVAPGVSLLPV--AMGEEEKDKWRRKVPLGRREASAEQIADAVIF 263 Query: 240 VIENP--FLNGEVIRLDGAIRM 259 ++ ++ G +I++DG + + Sbjct: 264 LVSGSAQYITGSIIKVDGGLSL 285 >1MG5-A nrPDB Length = 255 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 84/201 (41%), Gaps = 28/201 (13%) Query: 14 VITGGASGLGLSTAKRLVGQG-ATAVLLDV---PNSEGETEAKKLGGNCIFAPANVTSE- 68 + G G+GL T+K L+ + V+LD P + E +A F P +VT Sbjct: 10 IFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPI 69 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ--RVINVNLIGTF 126 E L + +DV +N AGI L+D Q R I VN G Sbjct: 70 AETTKLLKTIFAQLKTVDVLINGAGI----------------LDDHQIERTIAVNYTGLV 113 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N ++ + +GG G+I N SV F YS +K +V T +A+ L Sbjct: 114 NT---TTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK-L 169 Query: 187 API-GIRVVTIAPGLFATPLL 206 API G+ T+ PG+ T L+ Sbjct: 170 APITGVTAYTVNPGITRTTLV 190 >4GKB-A nrPDB Length = 258 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/213 (25%), Positives = 83/213 (38%), Gaps = 29/213 (13%) Query: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 + P + + + + A+ FGR+D VN AG+ I + V +LE Sbjct: 59 YLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLER------ 112 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NLI + + P RG I+N +S A GQ + Y ASKG + +T Sbjct: 113 -NLIHYYAMAHYCV-------PHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALT 164 Query: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTL------PDKVRNFLASQVPFPSRLGDPAEY 233 A L G+RV + P TPL P+ +A++VP R P E Sbjct: 165 REWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEI 224 Query: 234 AHLVQMVI---------ENPFLNGEVIRLDGAI 257 A ++ E F++G LD A+ Sbjct: 225 ADTAVFLLSPRASHTTGEWLFVDGGYTHLDRAL 257 >4HBG-A nrPDB Length = 286 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 32/171 (18%) Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGI---AVAIKTYHEKKNQVHTLEDFQ 115 +F P N S E + +++ +NCAG+ +++++T T Q Sbjct: 98 LFDPCNKWSNNERRYY----------VNLLINCAGLTQESLSVRT---------TASQIQ 138 Query: 116 RVINVNLIGTFNVIRLVAGVMGQNE---PDQGGQ--RGVIINTASVAAFEGQV---GQAA 167 ++NVN + + + M +++ P+ GQ R I+N +S+ G++ G + Sbjct: 139 DIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL-HSGKMKVPGTSV 197 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFA-TPLLTTLPDKVRNFL 217 YSASK + T +A ++ P IR TI+PGL T ++ LP + + L Sbjct: 198 YSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEML 248 >3GDF-A nrPDB Length = 267 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 62/231 (26%), Positives = 101/231 (43%), Gaps = 32/231 (13%) Query: 7 SVKGLVAVITG--GASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-----AKKLGGNCI 59 S+KG V V+TG G G+G+ A+ GA + ++G E K G Sbjct: 17 SLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAK 76 Query: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 V S + + + FG+ID + AG A A + ++E + V+ Sbjct: 77 AYKCQVDSYESCEKLVKDVVADFGQIDAFIANAG-ATADSGILDG-----SVEAWNHVVQ 130 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTAS----VAAFEGQVGQAAYSASKGGI 175 V+L GTF+ + V G + ++G G ++ TAS +A F + Q +Y+ +K G Sbjct: 131 VDLNGTFHCAKAV----GHHFKERG--TGSLVITASMSGHIANFPQE--QTSYNVAKAGC 182 Query: 176 VGMTLPIA---RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPF 223 + M +A RD A RV +I+PG T L +P + + S +P Sbjct: 183 IHMARSLANEWRDFA----RVNSISPGYIDTGLSDFVPKETQQLWHSMIPM 229 >2QHX-A nrPDB Length = 328 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 110/281 (39%), Gaps = 36/281 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 VA++TG A LG S A+ L +G AV L S E A N + +T + ++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEG-YAVCLHYHRSAAEANALSATLNARRPNSAITVQADL 106 Query: 72 Q-------------AALTL----------AKEKFGRIDVAVNCAGIAVAIKTYHEKKN-- 106 A +TL +GR DV VN A ++ Sbjct: 107 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 166 Query: 107 --QVHTLEDFQR----VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFE 160 V E + + N I + +I+ A + G IIN + Sbjct: 167 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 226 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQ 220 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+ Sbjct: 227 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSK 284 Query: 221 VPFPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRM 259 VP R AE + +V + + ++ G +++DG + Sbjct: 285 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2BFA-A nrPDB Length = 288 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 110/281 (39%), Gaps = 36/281 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 VA++TG A LG S A+ L +G AV L S E A N + +T + ++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEG-YAVCLHYHRSAAEANALSATLNARRPNSAITVQADL 66 Query: 72 Q-------------AALTL----------AKEKFGRIDVAVNCAGIAVAIKTYHEKKN-- 106 A +TL +GR DV VN A ++ Sbjct: 67 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 126 Query: 107 --QVHTLEDFQR----VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFE 160 V E + + N I + +I+ A + G IIN + Sbjct: 127 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 186 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQ 220 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+ Sbjct: 187 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSK 244 Query: 221 VPFPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRM 259 VP R AE + +V + + ++ G +++DG + Sbjct: 245 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >2AG5-A nrPDB Length = 246 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 90/203 (44%), Gaps = 30/203 (14%) Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +VT +K++ A E R+DV N AG H +D+ +N+N+ Sbjct: 58 DVTKKKQID---QFANE-VERLDVLFNVAGFV------HHGTVLDCEEKDWDFSMNLNVR 107 Query: 124 GTFNVIR-LVAGVMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLP 181 + +I+ + ++ Q + G IIN +SVA+ +G V + YS +K ++G+T Sbjct: 108 SMYLMIKAFLPKMLAQ-------KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS 160 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTL------PDKVRN-FLASQVPFPSRLGDPAEYA 234 +A D GIR + PG TP L P++ RN FL Q R E A Sbjct: 161 VAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK--TGRFATAEEIA 218 Query: 235 HLVQMVI--ENPFLNGEVIRLDG 255 L + E+ ++ G + +DG Sbjct: 219 MLCVYLASDESAYVTGNPVIIDG 241 >2NWQ-A nrPDB Length = 272 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 77/188 (40%), Gaps = 12/188 (6%) Query: 15 ITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA--NVTSEKEVQ 72 ITG SG G + A+R G + VL + A +L P +V + Sbjct: 26 ITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRAAMS 85 Query: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 AA+ E+F + +N AG+A+ Q L+D+ +++ N+ G RL+ Sbjct: 86 AAVDNLPEEFATLRGLINNAGLALGTD-----PAQSCDLDDWDTMVDTNIKGLLYSTRLL 140 Query: 133 AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 + + G I+N SVA G Y +K + +L + DL G+R Sbjct: 141 LPRLIAH-----GAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVR 195 Query: 193 VVTIAPGL 200 V + PGL Sbjct: 196 VTNLEPGL 203 >3PXX-A nrPDB Length = 287 Score = 50.1 bits (118), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 60/229 (26%), Positives = 85/229 (37%), Gaps = 42/229 (18%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS---------------EGETEAK 52 V+ V ++TGGA G G S A +L +GA +L D+ + E E + Sbjct: 8 VQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVE 67 Query: 53 KLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE 112 K G A +V V L A +FG++DV V AGI ++ Sbjct: 68 KTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGIC--------PLGAHLPVQ 119 Query: 113 DFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAF-----------EG 161 F +V+ +G N + + II T SVA Sbjct: 120 AFADAFDVDFVGVINTVHAALPYLTSG--------ASIITTGSVAGLIAAAQPPGAGGPQ 171 Query: 162 QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLP 210 G A YS +K + TL +A LAP IR I P T +L + P Sbjct: 172 GPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAP 220 >3V8B-A nrPDB Length = 283 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 59/195 (30%), Positives = 90/195 (46%), Gaps = 12/195 (6%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL---GGNCIFAPANVTSE 68 VA+ITG SG+G +TA L G T L +E E A ++ GG I A+V+ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +++ A+ KFG +D+ V AGI + K ++ I VNL GTF Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPF-----EWDETIAVNLRGTFLT 144 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + L + Q +GG V++++ + G AY+A+K V + +A +L Sbjct: 145 LHLTVPYLKQ----RGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGK 200 Query: 189 IGIRVVTIAPGLFAT 203 IRV + PG T Sbjct: 201 HHIRVNAVCPGAIET 215 >1P33-A nrPDB Length = 289 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 67/276 (24%), Positives = 111/276 (40%), Gaps = 34/276 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVL-LDVPNSEGETEAKKLGG----NCIFAPANVT 66 VA++TG A LG S A+ L +G T L ++ T A L + I A+++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 67 -------SEKEVQAALTLAKE----------KFGRIDVAVNCAG----IAVAIKTYHEKK 105 SE + +TL +GR DV VN A + K E Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 106 NQVHTLEDFQ----RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG 161 + V E + + N I + +I+ A + +Q G I+N + Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 162 QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV 221 +G Y+ +K + G+T A +LA + IRV ++PGL P +P V+ +V Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--DDMPFSVQEDYRRKV 246 Query: 222 PFPSRLGDPAEYAHLVQMVI--ENPFLNGEVIRLDG 255 P R E + +V + + ++ G I++DG Sbjct: 247 PLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDG 282 >3D3W-A nrPDB Length = 244 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 59/232 (25%), Positives = 104/232 (44%), Gaps = 26/232 (11%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 ++TG G+G T + L GA V + ++ ++ ++ G P V + Sbjct: 11 LVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG---IEP--VCVDLGDWE 65 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVA 133 A A G +D+ VN A +A+ ++ + E T E F R VNL V ++VA Sbjct: 66 ATERALGSVGPVDLLVNNAAVAL-LQPFLEV-----TKEAFDRSFEVNLRAVIQVSQIVA 119 Query: 134 -GVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIR 192 G++ + P G I+N +S + + Y ++KG + +T +A +L P IR Sbjct: 120 RGLIARGVP------GAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIR 173 Query: 193 VVTIAPGLFATPL---LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 V + P + T + + P K + L +++P LG AE H+V ++ Sbjct: 174 VNAVNPTVVMTSMGQATWSDPHKAKTML-NRIP----LGKFAEVEHVVNAIL 220 >3OIC-A nrPDB Length = 258 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 60/253 (23%), Positives = 109/253 (43%), Gaps = 25/253 (9%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNS-----EGETEAKKLGGNCIFAPANVTS 67 A++TG + G+G + A RL G ++++ S E E +KLG + ANV Sbjct: 7 ALVTGSSRGVGKAAAIRLAENGYN-IVINYARSKKAALETAEEIEKLGVKVLVVKANVGQ 65 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLED--FQRVINVNLIGT 125 +++ E FGR+DV VN A V V LE+ + +N+N Sbjct: 66 PAKIKEMFQQIDETFGRLDVFVNNAASGVL--------RPVMELEETHWDWTMNINAKAL 117 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + A +M +N GG G I++ +S+ + SK + +T +A + Sbjct: 118 LFCAQEAAKLMEKN----GG--GHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVE 171 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPS-RLGDPAEYAHLVQMVIENP 244 L+P I V ++ G T L P++ ++ P+ R+ + + V+ ++ + Sbjct: 172 LSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSK 231 Query: 245 --FLNGEVIRLDG 255 + G+ I +DG Sbjct: 232 ADMIRGQTIIVDG 244 >4EGF-A nrPDB Length = 266 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 80/268 (29%), Positives = 112/268 (41%), Gaps = 26/268 (9%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG---GNCI 59 A V + G A+ITG G+G A+ GA VL SE + + LG G + Sbjct: 13 AGVLRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDV 72 Query: 60 FAPANVTSEKEV-QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 A +E + A E FG +DV VN AGI+ H + + F I Sbjct: 73 HTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGIS------HPQPVVDTDPQLFDATI 126 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 VNL L+A +G+ G+ G II AS AA AY SK G+V Sbjct: 127 AVNL----RAPALLASAVGKAMV-AAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMA 181 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRL-----GDPAEY 233 T +AR+L P GIR ++ P T +LT + +V A P +R+ P E Sbjct: 182 TKVLARELGPHGIRANSVCP----TVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEV 237 Query: 234 AHLVQMVIEN--PFLNGEVIRLDGAIRM 259 + V + + +NG I +DG M Sbjct: 238 SDAVVWLASDAASMINGVDIPVDGGYTM 265 >1O5I-A nrPDB Length = 249 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 48/195 (24%), Positives = 88/195 (45%), Gaps = 16/195 (8%) Query: 70 EVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 +++ L L EK +D+ V AG A + E N EDF+ I+ + ++ Sbjct: 67 DLRKDLDLLFEKVKEVDILVLNAGGPKA-GFFDELTN-----EDFKEAIDSLFLNMIKIV 120 Query: 130 RLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI 189 R M ++G R V I + SV + + + ++++ + G ++ ++AP Sbjct: 121 RNYLPAM----KEKGWGRIVAITSFSVISPIENLYTS--NSARMALTGFLKTLSFEVAPY 174 Query: 190 GIRVVTIAPGLFATPLLTT-LPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--PFL 246 GI V +APG T + L ++ + + SQ+P R+ P E A +V + +L Sbjct: 175 GITVNCVAPGWTETERVKELLSEEKKKQVESQIPM-RRMAKPEEIASVVAFLCSEKASYL 233 Query: 247 NGEVIRLDGAIRMQP 261 G+ I +DG + P Sbjct: 234 TGQTIVVDGGLSKFP 248 >3O26-A nrPDB Length = 311 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 5/92 (5%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----NCIFAPAN 64 K AV+TGG G+G K+L G VL ++G +KL N +F + Sbjct: 11 KRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLD 70 Query: 65 VTSEKEVQAAL-TLAKEKFGRIDVAVNCAGIA 95 VT ++L K FG++D+ VN AG+A Sbjct: 71 VTDPIATMSSLADFIKTHFGKLDILVNNAGVA 102 >1A27-A nrPDB Length = 289 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 59/212 (27%), Positives = 91/212 (42%), Gaps = 29/212 (13%) Query: 12 VAVITGGASGLGLSTAKRLVGQGA-----TAVLLDVPNSEGETEAKKL----GGNCIFAP 62 V +ITG +SG+GL A RL + A L D+ EA + G+ Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V K V AA E GR+DV V AG+ + ++ V + V++VN+ Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 115 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 +GT +R++ + PD + G ++ T SV G Y ASK + G+ Sbjct: 116 VGT---VRMLQAFL----PDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 168 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKV 213 +A L P G+ + I G P+ T +KV Sbjct: 169 LAVLLLPFGVHLSLIECG----PVHTAFMEKV 196 >4DRY-A nrPDB Length = 281 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 13/142 (9%) Query: 48 ETEAKKLG---GNCIFA-PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHE 103 + A ++G GN + A +V +V A + +F R+D+ VN AG V E Sbjct: 71 DAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEE 130 Query: 104 KKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQV 163 T E + ++ NL G F + +M P +GG+ IIN S++A + Sbjct: 131 V-----TFEQWNGIVAANLTGAFLCTQHAFRMMKAQTP-RGGR---IINNGSISAQTPRP 181 Query: 164 GQAAYSASKGGIVGMTLPIARD 185 A Y+A+K I G+T A D Sbjct: 182 NSAPYTATKHAITGLTKSTALD 203 >6CGE-A nrPDB Length = 328 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 59/212 (27%), Positives = 91/212 (42%), Gaps = 29/212 (13%) Query: 12 VAVITGGASGLGLSTAKRLVGQGAT-----AVLLDVPNSEGETEAKKL----GGNCIFAP 62 V +ITG +SG+GL A RL + A L D+ EA + G+ Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V K V AA E GR+DV V AG+ + ++ V + V++VN+ Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 116 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 +GT +R++ + PD + G ++ T SV G Y ASK + G+ Sbjct: 117 VGT---VRMLQAFL----PDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 169 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKV 213 +A L P G+ + I G P+ T +KV Sbjct: 170 LAVLLLPFGVHLSLIECG----PVHTAFMEKV 197 >1FJH-A nrPDB Length = 257 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Query: 162 QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTT-LPD-KVRNFLAS 219 Q G AY+ SK + A G+R+ TIAPG TPLL L D + +A Sbjct: 149 QGGNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAK 208 Query: 220 QVPFPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGAIR--MQP 261 VP R +P+E A ++ ++ +++G I +DG I M+P Sbjct: 209 FVPPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGIDAVMRP 254 >5LCX-A nrPDB Length = 316 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 7/90 (7%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-------GGNCIFAPANV 65 A++TG G+G ++L +G +L G +KL +F +V Sbjct: 10 ALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDV 69 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIA 95 T V A K KFG++D+ VN AG++ Sbjct: 70 TDLASVAAVAVFIKSKFGKLDILVNNAGVS 99 >3KZV-A nrPDB Length = 254 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 42/206 (20%), Positives = 89/206 (43%), Gaps = 16/206 (7%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA--KKLGGNCIFAPANVTS 67 G V ++TG + G+G S L V+ V SE + +K G + ++T Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + ++ + A + G+ID V AG+ ++ +E + ++++ ++N F+ Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEID-----VNAWKKLYDINF---FS 113 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 ++ LV G P+ G ++ +S A AY +SK + + +A + Sbjct: 114 IVSLV----GIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANEER 169 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKV 213 ++ + +APG+ T + + + V Sbjct: 170 Q--VKAIAVAPGIVDTDMQVNIRENV 193 >3E9N-A nrPDB Length = 245 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 60/238 (25%), Positives = 96/238 (40%), Gaps = 26/238 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 S+K +AV+TG G+G+ K L L N E ++ G P Sbjct: 2 SLKKKIAVVTGATGGMGIEIVKDLSRDHIVYALGR--NPEHLAALAEIEG---VEPIESD 56 Query: 67 SEKEVQAALTLAKEK-FGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 KEV + K K +D V+ A +A + + ++ ++ +++N+I Sbjct: 57 IVKEVLEEGGVDKLKNLDHVDTLVHAAAVA------RDTTIEAGSVAEWHAHLDLNVIVP 110 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + R Q P G +I S A G Y+ASK + G+ ++ Sbjct: 111 AELSR-------QLLPALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKE 163 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKV-RNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 A GIRV T++PG TP+L L D NF P +P E A+ ++ VI+ Sbjct: 164 EANNGIRVSTVSPGPTNTPMLQGLMDSQGTNF------RPEIYIEPKEIANAIRFVID 215 >5L51-A nrPDB Length = 324 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 41/164 (25%), Positives = 64/164 (39%), Gaps = 36/164 (21%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLG---GNCIFAPA-N 64 AV+TG G+G K+L +G T +L G E K+LG G+ + + + Sbjct: 18 AVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQLD 77 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGI--------------------------AVAI 98 V V A + K KFG +D+ VN AG+ A Sbjct: 78 VADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSGAAKT 137 Query: 99 KTYHEKKN--QVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNE 140 + YH K V T+E + I N G+ V + ++ Q++ Sbjct: 138 EPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSD 181 >3UCF-A nrPDB Length = 223 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 5/84 (5%) Query: 175 IVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTL--PDKVRNFLASQVPFP-SRLGDPA 231 I T +A++LAPI RV I+PGL T + D+ + +Q P ++G+ + Sbjct: 137 IEATTKVLAKELAPI--RVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEAS 194 Query: 232 EYAHLVQMVIENPFLNGEVIRLDG 255 + A I+N ++ G VI +DG Sbjct: 195 DIAMAYLFAIQNSYMTGTVIDVDG 218 >2YW9-A nrPDB Length = 261 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 62/217 (28%), Positives = 94/217 (43%), Gaps = 27/217 (12%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVL---LDVPNSEGETEAKKLGGNCIFAPANV 65 K LV +T S LG + A +L GA L + E E A+ LGG +F A+V Sbjct: 10 KALVMGVTNQRS-LGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLF-RADV 67 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 T ++E+ A KE FG +D V+ IA A + E + +D+ + V+ Sbjct: 68 TQDEELDALFAGVKEAFGGLDYLVHA--IAFAPREAMEGRYIDTRRQDWLLALEVSAYSL 125 Query: 126 FNVIRLVAGVMGQNEP--DQGGQRGVIINTASVAAFEGQVGQAAYSA-SKGGIVGMTLPI 182 V R + EP +GG G++ T + A E V + A +K + + Sbjct: 126 VAVAR-------RAEPLLREGG--GIV--TLTYYASEKVVPKYNVMAIAKAALEASVRYL 174 Query: 183 ARDLAPIGIRVVTIAPGLFAT------PLLTTLPDKV 213 A +L P G+RV I+ G T P T + D+V Sbjct: 175 AYELGPKGVRVNAISAGPVRTVAARSIPGFTKMYDRV 211 >2DKN-A nrPDB Length = 255 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 69/280 (24%), Positives = 105/280 (37%), Gaps = 70/280 (25%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 V ITG ASG+G + + L G T + +D ++ E + GG E V Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGR----------ETAV 52 Query: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRL 131 A L G +D V CAG+ V T + V+ VN G ++ Sbjct: 53 AAVLDRCG---GVLDGLVCCAGVGV-------------TAANSGLVVAVNYFGVSALLD- 95 Query: 132 VAGVMGQNEPDQGGQRGVIINTASVAAFE------------------------GQVGQA- 166 G E GQ+ + S+AA + Q GQ Sbjct: 96 -----GLAEALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTH 150 Query: 167 -AYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTT------LPDKVRNFLAS 219 AY+ SK + + D A G+R+ +APG TPLL + R F+A Sbjct: 151 LAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVA- 209 Query: 220 QVPFPSRLGDPAEYAHLVQMVI--ENPFLNGEVIRLDGAI 257 P R +P E A + ++ + F++G V+ +DG + Sbjct: 210 --PL-GRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGM 246 >1N5D-A nrPDB Length = 288 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 10/122 (8%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPN-SEGETEAKKL---GGNCIFAPANVTS 67 VA++TG G+G + + L Q A V+L + + G+ K+L G + F ++ Sbjct: 6 VALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDIID 65 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + ++A ++++G +DV VN A IA + + H + + N +GT N Sbjct: 66 LQSIRALCDFLRKEYGGLDVLVNNAAIAFQL----DNPTPFHIQAEL--TMKTNFMGTRN 119 Query: 128 VI 129 V Sbjct: 120 VC 121 >3BHI-A nrPDB Length = 276 Score = 35.0 bits (79), Expect = 0.032, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 4/91 (4%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPN-SEGETEAKKLGGNCI---FAPANVTS 67 VA++TGG G+GL+ + L + V+L + + G+ ++L + F ++ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAI 98 + ++A ++++G +DV VN AGIA + Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGIAFKV 96 >3U4C-A nrPDB Length = 281 Score = 34.7 bits (78), Expect = 0.044, Method: Compositional matrix adjust. Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 31/262 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVL--LDVPNSEGETE---AKKLGGNCIFAPANVT 66 A + G + G+G + A +L Q + V+ ++ N E E AK + I +++ Sbjct: 25 TAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMS 84 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + + + GR+DV +N I + N +ED + Sbjct: 85 DQHTRAGIFQKIESQCGRLDVLIN--NIPGGAPDTFDNCN----IEDMTATFTQKTVAYI 138 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + I+ + +M QNE G IIN E S ++ + I+ L Sbjct: 139 DAIKRASSLMKQNE------FGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQL 192 Query: 187 APIGIRVVTIAPGLFATPLLTTLPD-----------KVRNFLASQVPFPSRLGDPAEYAH 235 AP I V + PG AT + K +AS +P R+G E A Sbjct: 193 APHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPM-KRVGSAEETAA 251 Query: 236 LVQMVI--ENPFLNGEVIRLDG 255 L + E ++ G+ I DG Sbjct: 252 LAAFLASEEASYITGQQISADG 273 >2HRB-A nrPDB Length = 274 Score = 32.3 bits (72), Expect = 0.19, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 47/88 (53%), Gaps = 4/88 (4%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPN-SEGETEAKKLGGNCI---FAPANVTS 67 VA++TG G+GL+ A+ L Q + V+L + + G+ ++L + F ++ Sbjct: 4 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 63 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIA 95 + ++A ++++G ++V VN A +A Sbjct: 64 LQSIRALRDFLRKEYGGLNVLVNNAAVA 91 >3U9L-A nrPDB Length = 324 Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust. Identities = 54/205 (26%), Positives = 92/205 (44%), Gaps = 29/205 (14%) Query: 12 VAVITGGASGLGLSTAKRLVGQG--ATAVLLDVPNSEGETEAKKLGGNCIFAPAN----V 65 + +ITG +SG G TA+ L G G A + D+ + + + G FA N Sbjct: 7 IILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNA-SNVEAIAG---FARDNDVDLR 62 Query: 66 TSEKEVQAALTLAKE------KFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 T E +VQ+ +++ + + GRIDV ++ AG V + T E F + + Sbjct: 63 TLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVF------GPAEAFTPEQFAELYD 116 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQ-AAYSASKGGIVGM 178 +N++ T V R M + + G++I +S ++ G A Y A+K + + Sbjct: 117 INVLSTQRVNRAALPHMRRQ------KHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAI 170 Query: 179 TLPIARDLAPIGIRVVTIAPGLFAT 203 + AR+L+ GI I PG F + Sbjct: 171 AVQYARELSRWGIETSIIVPGAFTS 195 >5LV0-A nrPDB Length = 686 Score = 31.2 bits (69), Expect = 0.44, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 22/32 (68%) Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAG 93 P +V+S+KEV+AA T A ++ R D+ ++ G Sbjct: 91 PQHVSSDKEVRAASTEADKRLSRFDIEMSMRG 122 >4Z3K-A nrPDB Length = 275 Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust. Identities = 38/165 (23%), Positives = 69/165 (41%), Gaps = 15/165 (9%) Query: 46 EGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKE-----KFGRIDVAVNCAGIAVAIKT 100 E E A++ G + PA++ +E +Q L +E R+ + N + K Sbjct: 65 EAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKG 124 Query: 101 YHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFE 160 + + L D +V N + +++ L + V+ + PD G ++N +S+ A + Sbjct: 125 FVD-------LSDSTQVNNYWALNLTSMLCLTSSVL-KAFPDSPGLNRTVVNISSLCALQ 176 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205 G A Y A K + +A L +RV+ APG T + Sbjct: 177 PFKGWALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGPLDTDM 219 >4FXY-P nrPDB Length = 693 Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVN 90 P +V+S++EV+AA T A +K R D+ ++ Sbjct: 98 PQHVSSDREVRAASTEADKKLSRFDIEMS 126 >4HWK-A nrPDB Length = 288 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 38/165 (23%), Positives = 69/165 (41%), Gaps = 15/165 (9%) Query: 46 EGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKE-----KFGRIDVAVNCAGIAVAIKT 100 E E A++ G + PA++ +E +Q L +E R+ + N + K Sbjct: 78 EAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKG 137 Query: 101 YHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFE 160 + + L D +V N + +++ L + V+ + PD G ++N +S+ A + Sbjct: 138 FVD-------LSDSTQVNNYWALNLTSMLCLTSSVL-KAFPDSPGLNRTVVNISSLCALQ 189 Query: 161 GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205 G A Y A K + +A L +RV+ APG T + Sbjct: 190 PFKGWALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGPLDTDM 232 >4LN1-A nrPDB Length = 336 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATA--VLLDVPNSEGETEAKKLGGNCIFAPA 63 KG+ V+ G +G S A ++ Q VL+DV ++ E EA L FAPA Sbjct: 25 KGINRVVLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPA 81 >4EJ6-A nrPDB Length = 370 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 VA++ GG GL RL G AT V+L + A+++G P+ + + Sbjct: 186 VAILGGGVIGLLTVQLARLAG--ATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEAI 243 Query: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIK 99 + L G +DV + CAG+A +K Sbjct: 244 AGPVGLVP---GGVDVVIECAGVAETVK 268 >2EFY-A nrPDB Length = 304 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 5/39 (12%) Query: 171 SKGGIVGMTLPIARDLAPIGIRVVTIAPG----LFATPL 205 S GGIV L +AR+L P G RV I+P +TPL Sbjct: 263 SSGGIVWAALQVARELGP-GKRVACISPDGGWKYLSTPL 300 >3COS-A nrPDB Length = 381 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 8/78 (10%) Query: 18 GASGLGLSTAKRLVGQGATAVL-LDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA-L 75 G G+GLS GA+ ++ +D+ NSE +AK LG P ++ K +Q + Sbjct: 206 GLGGVGLSAVMGCKAAGASRIIGIDI-NSEKFVKAKALGATDCLNPRDL--HKPIQEVII 262 Query: 76 TLAKEKFGRIDVAVNCAG 93 L K G +D A++CAG Sbjct: 263 ELTK---GGVDFALDCAG 277 >1W73-A nrPDB Length = 302 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 64/259 (24%), Positives = 101/259 (38%), Gaps = 23/259 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVL----LDVPNSEGETEAKKLGGNCIFAP 62 S +G VA ITGG +GLG L GA V+ +DV + E + + G Sbjct: 23 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 82 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V VQ ++ + G ++ +N A T N T+ D V+N Sbjct: 83 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDI--VLNGTA 140 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS-KGGIVGMTLP 181 T + + + Q+G + + E G SAS K G+ M+ Sbjct: 141 FVTLEIGKQLI----------KAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKS 190 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNF---LASQVPFPSRLGDPAEYAHLVQ 238 +A + G+R I PG T + D F + ++P RLG E A+L Sbjct: 191 LAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPC-GRLGTVEELANLAA 249 Query: 239 MVIEN--PFLNGEVIRLDG 255 + + ++NG VI+ DG Sbjct: 250 FLCSDYASWINGAVIKFDG 268 >4B1B-A nrPDB Length = 542 Score = 27.7 bits (60), Expect = 4.7, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 5/48 (10%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDV--PNSEGETEAKKLGGNCI 59 V+ GG G G+++AK GA +L D P+S+G +GG C+ Sbjct: 46 VVIGGGPG-GMASAKEAAAHGARVLLFDYVKPSSQGTKWG--IGGTCV 90 >3K4W-A nrPDB Length = 291 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 9/17 (52%), Positives = 15/17 (88%) Query: 189 IGIRVVTIAPGLFATPL 205 +GIR+V + PG++ATP+ Sbjct: 117 LGIRIVNLEPGVWATPM 133 >5FDF-A nrPDB Length = 337 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 2 AAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVP 43 AA+ V VI GG+ G G++ A + + A A+L DVP Sbjct: 183 AASFPQVDQERIVIAGGSQGGGIALAVSALSKKAKALLCDVP 224 >5HFN-A nrPDB Length = 311 Score = 27.3 bits (59), Expect = 7.6, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 2 AAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVP 43 AA+ V VI GG+ G G++ A + + A A+L DVP Sbjct: 157 AASFPQVDQERIVIAGGSQGGGIALAVSALSKKAKALLCDVP 198 >3IP1-A nrPDB Length = 404 Score = 26.9 bits (58), Expect = 8.6, Method: Compositional matrix adjust. Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 4/62 (6%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 VI GG +GL+ L GA+ V+L P+ AK+LG + + P T E V+A Sbjct: 218 VILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDP---TKENFVEA 273 Query: 74 AL 75 L Sbjct: 274 VL 275 >4WOK-A nrPDB Length = 336 Score = 26.9 bits (58), Expect = 9.7, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 8/74 (10%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 ++ GGA +G TAK L GQG V+ D S G A + G F ++ QA Sbjct: 15 LVVGGAGFIGSHTAKLLAGQGYAPVVYD-NLSTGHQSAVRWGD---FVEGDILD----QA 66 Query: 74 ALTLAKEKFGRIDV 87 L EK+ + V Sbjct: 67 RLVETMEKYAPVAV 80 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1E3W-A nrPDB 304 4e-83 2O23-A nrPDB 297 3e-81 2PNF-A nrPDB 275 1e-74 2HQ1-A nrPDB 267 5e-72 4JRO-A nrPDB 266 8e-72 3RSH-A nrPDB 265 1e-71 2UVD-A nrPDB 265 1e-71 3OSU-A nrPDB 264 2e-71 2C07-A nrPDB 260 4e-70 5CDY-A nrPDB 258 2e-69 3EMK-A nrPDB 258 2e-69 1Q7C-A nrPDB 257 3e-69 3LYL-A nrPDB 255 1e-68 3F9I-A nrPDB 252 1e-67 3WOH-A nrPDB 251 2e-67 3FTP-A nrPDB 249 8e-67 3GRP-A nrPDB 245 2e-65 4BO1-A nrPDB 244 3e-65 1GEE-A nrPDB 243 6e-65 4M8S-A nrPDB 242 1e-64 5ITV-A nrPDB 242 1e-64 3AUT-A nrPDB 242 2e-64 4NBT-A nrPDB 240 4e-64 4CQL-A nrPDB 239 8e-64 3EZL-A nrPDB 238 2e-63 4K6F-A nrPDB 237 3e-63 2PH3-A nrPDB 237 3e-63 4KMS-A nrPDB 237 4e-63 4DMM-A nrPDB 237 4e-63 4RZH-A nrPDB 237 5e-63 4IIN-A nrPDB 236 7e-63 2CDH-G nrPDB 235 1e-62 2NM0-A nrPDB 234 3e-62 3VZS-A nrPDB 234 3e-62 4NBV-A nrPDB 234 4e-62 3O4R-A nrPDB 233 8e-62 4CQM-B nrPDB 232 2e-61 3OEC-A nrPDB 230 7e-61 6NRP-A nrPDB 229 1e-60 2ZAT-A nrPDB 228 2e-60 1GEG-A nrPDB 227 3e-60 1AE1-A nrPDB 227 5e-60 5VT6-A nrPDB 227 5e-60 1NFF-A nrPDB 226 6e-60 2EW8-A nrPDB 226 8e-60 5OJG-A nrPDB 225 2e-59 5OVL-A nrPDB 223 6e-59 2AE2-A nrPDB 223 7e-59 4RZI-B nrPDB 222 1e-58 4Z9Y-A nrPDB 222 1e-58 5T5Q-A nrPDB 220 7e-58 5U9P-A nrPDB 219 1e-57 5OVJ-A nrPDB 218 3e-57 4IIV-A nrPDB 217 4e-57 3PPI-A nrPDB 217 6e-57 6CI9-A nrPDB 216 8e-57 3RWB-A nrPDB 216 9e-57 1YXM-A nrPDB 216 9e-57 3WTC-A nrPDB 214 3e-56 1UZM-A nrPDB 214 3e-56 4IS3-A nrPDB 212 1e-55 2Q2Q-A nrPDB 212 1e-55 2HSD-A nrPDB 212 1e-55 3V2G-A nrPDB 211 3e-55 3WYE-A nrPDB 211 3e-55 3R3S-A nrPDB 210 5e-55 2CFC-A nrPDB 210 6e-55 2X9N-A nrPDB 209 9e-55 3UVE-A nrPDB 209 1e-54 3W8F-A nrPDB 208 2e-54 3T7C-A nrPDB 207 3e-54 4MOW-A nrPDB 207 6e-54 1AHH-A nrPDB 205 2e-53 1DOH-A nrPDB 205 2e-53 1K2W-A nrPDB 204 4e-53 4HP8-A nrPDB 203 5e-53 1HXH-A nrPDB 203 6e-53 3V2H-A nrPDB 202 9e-53 5YSS-A nrPDB 202 1e-52 4DBZ-A nrPDB 202 1e-52 4E6P-A nrPDB 202 2e-52 3A28-C nrPDB 202 2e-52 5EJ2-A nrPDB 202 2e-52 3U5T-A nrPDB 201 2e-52 2B4Q-A nrPDB 200 4e-52 1X1T-A nrPDB 200 4e-52 3OIC-A nrPDB 200 6e-52 2GDZ-A nrPDB 198 2e-51 5B1Y-A nrPDB 195 2e-50 1P33-A nrPDB 193 5e-50 2QHX-A nrPDB 192 1e-49 2BFA-A nrPDB 192 1e-49 4FC7-A nrPDB 191 2e-49 4AVY-A nrPDB 191 3e-49 3ZV3-A nrPDB 189 1e-48 5JS6-A nrPDB 188 2e-48 1O5I-A nrPDB 188 2e-48 3UF0-A nrPDB 188 3e-48 3GDF-A nrPDB 187 4e-48 3D3W-A nrPDB 187 5e-48 4TRR-A nrPDB 185 1e-47 3UN1-A nrPDB 185 1e-47 4CR6-A nrPDB 185 2e-47 2AG5-A nrPDB 185 2e-47 1H5Q-A nrPDB 184 4e-47 1CYD-A nrPDB 182 1e-46 2BGM-A nrPDB 182 1e-46 1BDB-A nrPDB 182 1e-46 5IZ4-A nrPDB 181 2e-46 4RGB-A nrPDB 180 5e-46 4DA9-A nrPDB 180 5e-46 5JY1-A nrPDB 179 9e-46 5O3Z-A nrPDB 176 5e-45 3V8B-A nrPDB 176 7e-45 2FWM-X nrPDB 175 2e-44 3PXX-A nrPDB 170 4e-43 3OML-A nrPDB 170 8e-43 4EGF-A nrPDB 169 1e-42 4GKB-A nrPDB 166 7e-42 2NWQ-A nrPDB 162 2e-40 3RKU-A nrPDB 160 5e-40 5ILO-A nrPDB 158 2e-39 4DRY-A nrPDB 145 2e-35 4HBG-A nrPDB 139 1e-33 1A27-A nrPDB 135 2e-32 6CGE-A nrPDB 134 4e-32 1B15-A nrPDB 127 5e-30 1MG5-A nrPDB 119 1e-27 3O26-A nrPDB 118 4e-27 1FJH-A nrPDB 109 1e-24 5LCX-A nrPDB 91 6e-19 Sequences not found previously or not previously below threshold: 3U4C-A nrPDB 147 5e-36 1W73-A nrPDB 138 2e-33 2P91-A nrPDB 138 3e-33 2YW9-A nrPDB 132 1e-31 3KZV-A nrPDB 127 5e-30 2HRB-A nrPDB 122 2e-28 3E9N-A nrPDB 120 5e-28 5L51-A nrPDB 117 5e-27 5PGZ-A nrPDB 113 6e-26 3DWF-A nrPDB 113 7e-26 1N5D-A nrPDB 113 8e-26 3OIG-A nrPDB 112 1e-25 4M89-A nrPDB 112 2e-25 5YCX-A nrPDB 111 2e-25 5KOI-A nrPDB 111 3e-25 5TF4-A nrPDB 110 6e-25 3BHI-A nrPDB 109 1e-24 4NR0-A nrPDB 109 1e-24 3GRK-A nrPDB 109 1e-24 5CFZ-A nrPDB 108 2e-24 4JQC-A nrPDB 108 3e-24 2DKN-A nrPDB 108 3e-24 3K2E-A nrPDB 106 1e-23 4ZJU-A nrPDB 105 2e-23 1SNY-A nrPDB 105 2e-23 5I9N-A nrPDB 104 3e-23 4ALL-A nrPDB 102 2e-22 3UCF-A nrPDB 101 3e-22 4J3F-A nrPDB 100 8e-22 4HWK-A nrPDB 96 1e-20 4Z3K-A nrPDB 96 2e-20 4NK4-A nrPDB 93 9e-20 1OAA-A nrPDB 90 1e-18 3U9L-A nrPDB 89 2e-18 2PD3-A nrPDB 89 2e-18 5WQO-A nrPDB 88 4e-18 5TQV-A nrPDB 88 5e-18 4Q9N-A nrPDB 87 8e-18 2NTV-A nrPDB 83 1e-16 1ENP-A nrPDB 82 2e-16 4OYR-A nrPDB 80 1e-15 2O2S-A nrPDB 77 6e-15 2PTG-A nrPDB 70 8e-13 3F4B-A nrPDB 68 4e-12 3SLK-A nrPDB 61 5e-10 4LIS-A nrPDB 56 1e-08 3ORF-A nrPDB 55 4e-08 1DIR-A nrPDB 53 1e-07 2O2Y-A nrPDB 51 6e-07 1OOE-A nrPDB 49 2e-06 1UDA-A nrPDB 48 5e-06 6BWL-A nrPDB 48 5e-06 3ENK-A nrPDB 46 1e-05 4R1T-A nrPDB 46 2e-05 3RFT-A nrPDB 46 2e-05 1Z45-A nrPDB 43 1e-04 2PK3-A nrPDB 43 1e-04 5N2I-A nrPDB 40 0.001 6ACF-A nrPDB 40 0.001 2Z95-A nrPDB 40 0.001 2P4H-X nrPDB 39 0.002 1I3M-A nrPDB 39 0.002 1VL0-A nrPDB 39 0.002 4PVC-A nrPDB 39 0.002 5K1S-A nrPDB 39 0.002 1R66-A nrPDB 39 0.002 3VPX-A nrPDB 39 0.002 2GN9-A nrPDB 39 0.003 6DEB-A nrPDB 38 0.003 4J6F-A nrPDB 38 0.003 2HUN-A nrPDB 38 0.003 1LU9-A nrPDB 38 0.003 5INT-A nrPDB 38 0.004 1BXK-A nrPDB 38 0.005 2Q1W-A nrPDB 38 0.006 4G5H-A nrPDB 37 0.007 4A10-A nrPDB 37 0.010 1WVG-A nrPDB 36 0.012 1ZDL-A nrPDB 36 0.014 4EUF-A nrPDB 36 0.015 2C20-A nrPDB 36 0.015 4K28-A nrPDB 36 0.017 4EJ6-A nrPDB 36 0.020 5F5N-A nrPDB 36 0.020 1U3W-A nrPDB 35 0.025 3IP1-A nrPDB 35 0.025 1JPH-A nrPDB 35 0.028 6G2J-P nrPDB 35 0.029 5YWN-A nrPDB 35 0.029 6GCS-E nrPDB 35 0.030 3OND-A nrPDB 35 0.031 5ENV-A nrPDB 35 0.031 6ACQ-A nrPDB 35 0.035 2V3C-C nrPDB 35 0.035 2EXX-A nrPDB 35 0.038 1GY8-A nrPDB 35 0.039 1O89-A nrPDB 35 0.041 2VN8-A nrPDB 34 0.044 2NNL-D nrPDB 34 0.049 1KEU-A nrPDB 34 0.051 2Q4B-A nrPDB 34 0.051 4J2O-A nrPDB 34 0.052 2PZM-A nrPDB 34 0.052 2DFV-A nrPDB 34 0.067 2HK7-A nrPDB 34 0.091 3DFZ-A nrPDB 33 0.095 1EE2-A nrPDB 33 0.096 5GUP-L nrPDB 33 0.097 5AOV-A nrPDB 33 0.11 3COS-A nrPDB 33 0.11 4DGK-A nrPDB 33 0.12 4UUP-A nrPDB 33 0.13 2C54-A nrPDB 33 0.13 1ZZE-A nrPDB 33 0.15 2EER-A nrPDB 33 0.16 4WOK-A nrPDB 33 0.17 3SXP-A nrPDB 33 0.18 3NJ4-A nrPDB 33 0.18 4KTT-E nrPDB 33 0.18 5B6K-A nrPDB 33 0.19 6BII-A nrPDB 32 0.22 6BMQ-A nrPDB 32 0.22 1OC2-A nrPDB 32 0.24 1HSZ-A nrPDB 32 0.25 1HSO-A nrPDB 32 0.25 1ID1-A nrPDB 32 0.28 4B1B-A nrPDB 32 0.31 1E3J-A nrPDB 31 0.38 3DMF-A nrPDB 31 0.38 3HZZ-A nrPDB 31 0.40 2WEK-A nrPDB 31 0.45 2GGS-A nrPDB 31 0.50 3F6S-A nrPDB 31 0.51 4KUG-A nrPDB 31 0.52 3LK7-A nrPDB 31 0.52 3CT4-A nrPDB 31 0.55 4XRR-A nrPDB 31 0.59 3JTJ-A nrPDB 31 0.64 4R1U-A nrPDB 31 0.65 3R9I-A nrPDB 31 0.68 4FP4-A nrPDB 31 0.70 3ZU2-A nrPDB 31 0.74 3BIC-A nrPDB 31 0.74 4KDR-A nrPDB 30 0.81 5JXW-A nrPDB 30 0.85 4KDC-A nrPDB 30 0.88 4QUK-A nrPDB 30 0.89 4BKP-A nrPDB 30 0.90 1QQV-A nrPDB 30 0.93 1JAY-A nrPDB 30 0.93 1YB5-A nrPDB 30 0.95 1EDZ-A nrPDB 30 1.0 3Q7E-A nrPDB 30 1.0 4EJ0-A nrPDB 30 1.1 2YQ5-A nrPDB 30 1.1 3VR3-A nrPDB 30 1.1 3MMP-A nrPDB 30 1.2 4PZE-A nrPDB 30 1.2 1DB3-A nrPDB 30 1.3 5GXF-A nrPDB 29 1.4 6C55-A nrPDB 29 1.5 4E0B-A nrPDB 29 1.5 3FBG-A nrPDB 29 1.5 3X2F-A nrPDB 29 1.5 2BC1-A nrPDB 29 1.8 3DQQ-A nrPDB 29 1.9 4GBJ-A nrPDB 29 1.9 5KXJ-A nrPDB 29 2.0 5B1I-A nrPDB 29 2.2 7REQ-A nrPDB 29 2.3 3K4W-A nrPDB 29 2.4 6GBN-A nrPDB 29 2.5 2D0I-A nrPDB 29 2.5 3WJN-A nrPDB 29 2.8 4A5O-A nrPDB 29 2.8 3H0K-A nrPDB 29 2.8 1NHQ-A nrPDB 29 2.8 1YXY-A nrPDB 29 3.0 4B3J-A nrPDB 28 3.4 2CF5-A nrPDB 28 3.5 4B4V-A nrPDB 28 4.0 3DC2-A nrPDB 28 4.1 3H9U-A nrPDB 28 4.2 4PC7-C nrPDB 28 4.2 2IUU-A nrPDB 28 4.5 4BM5-A nrPDB 28 4.5 4R16-A nrPDB 28 4.6 5TEN-A nrPDB 28 4.6 1EQ2-A nrPDB 28 4.7 2X86-A nrPDB 28 4.8 2Q4W-A nrPDB 28 5.0 2IUT-A nrPDB 28 5.0 2JLA-A nrPDB 28 5.0 5UOG-A nrPDB 28 5.1 1X74-A nrPDB 28 5.3 1P0F-A nrPDB 28 5.3 6MVR-A nrPDB 28 5.4 4B4O-A nrPDB 28 5.4 3R7T-A nrPDB 28 5.5 3SC6-A nrPDB 28 5.8 4OFX-A nrPDB 28 5.9 5TC4-A nrPDB 28 6.0 5ZZM-A nrPDB 28 6.1 4Z6K-A nrPDB 28 6.1 4NFY-A nrPDB 28 6.3 3S8M-A nrPDB 28 6.4 5XW3-A nrPDB 28 6.7 6BZ0-A nrPDB 27 7.1 4WEQ-A nrPDB 27 7.5 3G1U-A nrPDB 27 7.5 5T57-A nrPDB 27 7.7 3N58-A nrPDB 27 7.8 2EEZ-A nrPDB 27 7.8 4TSK-A nrPDB 27 8.1 5H7J-A nrPDB 27 8.5 4Y4N-A nrPDB 27 8.8 1XDW-A nrPDB 27 8.9 1UUF-A nrPDB 27 9.1 2R5U-A nrPDB 27 9.4 2EGU-A nrPDB 27 9.7 >1E3W-A nrPDB Length = 261 Score = 304 bits (778), Expect = 4e-83, Method: Composition-based stats. Identities = 260/261 (99%), Positives = 260/261 (99%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF Sbjct: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV Sbjct: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 PIARDLAPIGIRVVTIAPGLFATPLLTTLPD VRNFLASQVPFPSRLGDPAEYAHLVQMV Sbjct: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 241 IENPFLNGEVIRLDGAIRMQP 261 >2O23-A nrPDB Length = 265 Score = 297 bits (761), Expect = 3e-81, Method: Composition-based stats. Identities = 229/261 (87%), Positives = 246/261 (94%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 MAAA RSVKGLVAVITGGASGLGL+TA+RLVGQGA+AVLLD+PNS GE +AKKLG NC+F Sbjct: 3 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF 62 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 APA+VTSEK+VQ AL LAK KFGR+DVAVNCAGIAVA KTY+ KK Q HTLEDFQRV++V Sbjct: 63 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 122 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL+GTFNVIRLVAG MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL Sbjct: 123 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 182 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 PIARDLAPIGIRV+TIAPGLF TPLLT+LP+KV NFLASQVPFPSRLGDPAEYAHLVQ + Sbjct: 183 PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 242 Query: 241 IENPFLNGEVIRLDGAIRMQP 261 IENPFLNGEVIRLDGAIRMQP Sbjct: 243 IENPFLNGEVIRLDGAIRMQP 263 >2PNF-A nrPDB Length = 248 Score = 275 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 74/256 (28%), Positives = 126/256 (49%), Gaps = 19/256 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPA 63 ++G V+++TG G+G + A++L G+T ++ + A+++ G Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEM 64 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 N+ SE+ + A ID+ VN AGI +K +L D++ V+ VNL Sbjct: 65 NLLSEESINKAFEEIYNLVDGIDILVNNAGIT------RDKLFLRMSLLDWEEVLKVNLT 118 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GTF V + M + + G I+N +SV F G VGQ YS +K G++G T +A Sbjct: 119 GTFLVTQNSLRKMIKQ------RWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLA 172 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE- 242 ++LAP + V +APG T + L ++++ Q+P R G P E A++V + Sbjct: 173 KELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPL-GRFGSPEEVANVVLFLCSE 231 Query: 243 -NPFLNGEVIRLDGAI 257 ++ GEVI ++G + Sbjct: 232 LASYITGEVIHVNGGM 247 >2HQ1-A nrPDB Length = 247 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 85/259 (32%), Positives = 132/259 (50%), Gaps = 19/259 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLGGNCIFAP 62 +KG A++TG + GLG + A +L GA VL P S E K G N + A Sbjct: 2 QLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAK 61 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V + ++V+ + A + FGRID+ VN AGI + + +D+ V+N NL Sbjct: 62 GDVKNPEDVENMVKTAMDAFGRIDILVNNAGIT------RDTLMLKMSEKDWDDVLNTNL 115 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + V+ +M + + G IIN S+A G GQA Y+ASK G++G T I Sbjct: 116 KSAYLCTKAVSKIMLKQ------KSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSI 169 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 A++ A GI +APG+ T + LPDKV+ + +P R G P E A++V + Sbjct: 170 AKEFAAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPL-KRFGTPEEVANVVGFLAS 228 Query: 243 NP--FLNGEVIRLDGAIRM 259 + ++ G+VI +DG + M Sbjct: 229 DDSNYITGQVINIDGGLVM 247 >4JRO-A nrPDB Length = 271 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 86/263 (32%), Positives = 130/263 (49%), Gaps = 19/263 (7%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNC 58 + +++G VAV+TGG+ G+G A L +GA + E E KL G Sbjct: 22 SNAMTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEV 81 Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 ANV ++V A A E+FGR+D+ VN AGI K+++ + VI Sbjct: 82 EAMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDE------WDDVI 135 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 N+NL GTF + V+ M + + G IIN ASV G GQA Y ASK G++G+ Sbjct: 136 NINLKGTFLCTKAVSRTMMKQ------RAGKIINMASVVGLIGNAGQANYVASKAGVIGL 189 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 T AR+LAP GI V +APG T + L +K + + +Q+P G + A+ V Sbjct: 190 TKTTARELAPRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQIPL-GAYGTTEDIANAVL 248 Query: 239 MVIEN--PFLNGEVIRLDGAIRM 259 + + ++ G+ + +DG + M Sbjct: 249 FLASDASKYITGQTLSVDGGMVM 271 >3RSH-A nrPDB Length = 251 Score = 265 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 79/255 (30%), Positives = 129/255 (50%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 +++G VA++TG + G+G + A+ L +GA + S + + LG N NVT Sbjct: 9 NLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVT 68 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + + ++A L ++FG +D+ VN AGI K+ E++ ++ NL F Sbjct: 69 NPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKE------EEWSDIMETNLTSIF 122 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + ++G IIN SV G GQA Y+A+K G++G T +AR++ Sbjct: 123 RLSKAVLRGMMKK------RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREV 176 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NP 244 A G+ V T+APG T + L D+ R +QVP RLGDP E A V + Sbjct: 177 ASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQVP-AGRLGDPREIASAVAFLASPEAA 235 Query: 245 FLNGEVIRLDGAIRM 259 ++ GE + ++G + M Sbjct: 236 YITGETLHVNGGMYM 250 >2UVD-A nrPDB Length = 246 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 127/258 (49%), Gaps = 19/258 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA----KKLGGNCIFAPA 63 +KG VA++TG + G+G + A L QGA V+ N + E KKLG + I A Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + ++V + + FG++D+ VN AG+ K+ E++ VIN NL Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKE------EEWDTVINTNLK 115 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F + V+ M + + G I+N ASV G GQA Y A+K G++G+T A Sbjct: 116 GVFLCTKAVSRFMMRQ------RHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSA 169 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 ++LA I V IAPG AT + L + ++ + +P G+ + A+ V + Sbjct: 170 KELASRNITVNAIAPGFIATDMTDVLDENIKAEMLKLIPAAQ-FGEAQDIANAVTFFASD 228 Query: 244 --PFLNGEVIRLDGAIRM 259 ++ G+ + +DG + M Sbjct: 229 QSKYITGQTLNVDGGMVM 246 >3OSU-A nrPDB Length = 246 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 76/255 (29%), Positives = 122/255 (47%), Gaps = 19/255 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAPANVT 66 A++TG + G+G S A +L +G + + E E K G + ANV Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 EV+A + +FG +DV VN AGI K+ +++ VI+ NL G F Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKE------QEWDDVIDTNLKGVF 118 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N I+ M + + G IIN +SV G GQA Y A+K G++G+T AR+L Sbjct: 119 NCIQKATPQMLRQ------RSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAAREL 172 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--P 244 A GI V +APG + + L D+++ + +Q+P R G + A+ V + + Sbjct: 173 ASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLA-RFGQDTDIANTVAFLASDKAK 231 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ I ++G + M Sbjct: 232 YITGQTIHVNGGMYM 246 >2C07-A nrPDB Length = 285 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 120/255 (47%), Gaps = 18/255 (7%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPANV 65 + VA++TG G+G AK L + + + ++ E K G +V Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + ++E+ + + +D+ VN AGI K ++ ++ V+ NL Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDE------WEDVLRTNLNSL 156 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + ++ M N + G IIN +S+ G VGQA YS+SK G++G T +A++ Sbjct: 157 FYITQPISKRMINN------RYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKE 210 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP- 244 LA I V IAPG ++ + + ++++ + S +P R+G P E A+L + + Sbjct: 211 LASRNITVNAIAPGFISSDMTDKISEQIKKNIISNIP-AGRMGTPEEVANLACFLSSDKS 269 Query: 245 -FLNGEVIRLDGAIR 258 ++NG V +DG + Sbjct: 270 GYINGRVFVIDGGLS 284 >5CDY-A nrPDB Length = 244 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 76/255 (29%), Positives = 123/255 (48%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 S +G +A++TG + G+G + A+ LV +GA + E + LG N NV Sbjct: 2 SFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVV 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + L + +FG +D+ VN AGI K ++ +Q +I+ NL F Sbjct: 62 DPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDE------WQDIIDTNLTSVF 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + + G II SV G GQ Y+A+K G++G + +AR++ Sbjct: 116 RLSKAVMRAMMKK------RFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREV 169 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--P 244 A GI V +APG T + TL D R + +QVP +RLGD E A V + + Sbjct: 170 ASRGITVNVVAPGFIETDMTRTLTDDQRAGILAQVP-ANRLGDAKEIASAVAFLASDEAS 228 Query: 245 FLNGEVIRLDGAIRM 259 +++GE + ++G + M Sbjct: 229 YISGETLHVNGGMYM 243 >3EMK-A nrPDB Length = 246 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 126/258 (48%), Gaps = 15/258 (5%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 ++ + G A++TG GLG + A+ L QGA L + + A +LG PA Sbjct: 1 SMFDLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPA 60 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 N++ + V+A A+E+ G +D+ VN AGI + + ED+ V+ VNL Sbjct: 61 NLSDREAVKALGQKAEEEMGGVDILVNNAGIT------RDGLFVRMSDEDWDAVLTVNLT 114 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 FN+ R + M + + G IIN S+ G GQA Y ASK G++G + +A Sbjct: 115 SVFNLTRELTHPMMRR------RNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLA 168 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 +++A + V IAPG + + L +K ++ + +P R+G A+ A V + + Sbjct: 169 QEIASRNVTVNCIAPGFIESAMTGKLNEKQKDAIMGNIPM-KRMGVGADIAAAVVYLASD 227 Query: 244 --PFLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 228 EAAYVTGQTLHVNGGMAM 245 >1Q7C-A nrPDB Length = 244 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 72/255 (28%), Positives = 122/255 (47%), Gaps = 15/255 (5%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + +G +A++TG + G+G + A+ L +GA + + + + LG N NVT Sbjct: 2 NFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVT 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 +++ L + +FG +D+ VN AGI K E++ +I NL F Sbjct: 62 DPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKD------EEWNDIIETNLSSVF 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + + V M + + G II SV G GQA ++A+K G++G + +AR++ Sbjct: 116 RLSKAVMRAMMKK------RHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREV 169 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--P 244 A GI V +APG T + L D R + +QVP RLG E A+ V + + Sbjct: 170 ASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVP-AGRLGGAQEIANAVAFLASDEAA 228 Query: 245 FLNGEVIRLDGAIRM 259 ++ GE + ++G + M Sbjct: 229 YITGETLHVNGGMYM 243 >3LYL-A nrPDB Length = 247 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 68/258 (26%), Positives = 120/258 (46%), Gaps = 18/258 (6%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPA 63 S+ VA++TG + G+G A L +GAT V + E K+ G Sbjct: 2 SLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVL 61 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 N++ + +Q K + ID+ VN AGI + + +++Q VIN NL Sbjct: 62 NISDIESIQNFFAEIKAENLAIDILVNNAGIT------RDNLMMRMSEDEWQSVINTNLS 115 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F + + M + + G II+ SV G GQ Y A+K G++G + +A Sbjct: 116 SIFRMSKECVRGMMKK------RWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLA 169 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE- 242 ++A I V +APG AT + L D+ ++F+A+++P ++G+P + A V + Sbjct: 170 YEVASRNITVNVVAPGFIATDMTDKLTDEQKSFIATKIP-SGQIGEPKDIAAAVAFLASE 228 Query: 243 -NPFLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 229 EAKYITGQTLHVNGGMYM 246 >3F9I-A nrPDB Length = 249 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 65/257 (25%), Positives = 118/257 (45%), Gaps = 19/257 (7%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 + + G ++ITG +SG+G + A+ L G+ ++ + ++ L N N Sbjct: 9 MIDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCN 68 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 + +++E ++ +D+ V AGI K +DF +VI++NL Sbjct: 69 LANKEECSNLISKT----SNLDILVCNAGITSDTLAIRMKD------QDFDKVIDINLKA 118 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + R M Q + G IIN +S+ G GQA Y ASK G++GMT ++ Sbjct: 119 NFILNREAIKKMIQK------RYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSY 172 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE-- 242 ++A GI V +APG + + L +K R + ++P G P + A+ V + Sbjct: 173 EVATRGITVNAVAPGFIKSDMTDKLNEKQREAIVQKIPL-GTYGIPEDVAYAVAFLASNN 231 Query: 243 NPFLNGEVIRLDGAIRM 259 ++ G+ + ++G + M Sbjct: 232 ASYITGQTLHVNGGMLM 248 >3WOH-A nrPDB Length = 251 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 81/258 (31%), Positives = 127/258 (49%), Gaps = 21/258 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS----EGETEAKKLGGNCIFAPA 63 + G VA++TGG+ GLG + A RL GA ++ V + E + E ++LGG Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V+ ++V + G +D+ VN AGI + ED+ V+N NL Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILVNNAGI------IRDGLAASIKDEDYDAVMNTNLK 122 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F I+ + + G IIN +SV+ G GQA Y+++K G++G+T IA Sbjct: 123 GAFLFIKACYFGFIRK------RSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIA 176 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI-- 241 ++LA +R +APGL AT + L D + VP R G P E A LV + Sbjct: 177 KELAERNVRCNAVAPGLIATDMTQDLVDDSKR--LDPVPM-RRFGRPDEVAGLVAFLAGD 233 Query: 242 ENPFLNGEVIRLDGAIRM 259 E+ ++ G+V+ +DG + M Sbjct: 234 ESSYITGQVVCVDGGMAM 251 >3FTP-A nrPDB Length = 270 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 74/260 (28%), Positives = 119/260 (45%), Gaps = 18/260 (6%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCIFAP 62 +++ VA++TG + G+G + A L +GA + + E K+ G A Sbjct: 24 KTLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAV 83 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 NV V A + ++FG ++V VN AGI K ++ + VI+ NL Sbjct: 84 LNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDE------WDAVIDTNL 137 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F + R V M + + G I+N SV G GQ Y+A+K G+ GMT + Sbjct: 138 KAVFRLSRAVLRPMMK------ARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRAL 191 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 AR++ GI V +APG T + LP + + L +Q+P RLG P + AH V + Sbjct: 192 AREIGSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPL-GRLGSPEDIAHAVAFLAS 250 Query: 243 --NPFLNGEVIRLDGAIRMQ 260 ++ G + ++G + M Sbjct: 251 PQAGYITGTTLHVNGGMFMS 270 >3GRP-A nrPDB Length = 266 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 64/260 (24%), Positives = 116/260 (44%), Gaps = 15/260 (5%) Query: 2 AAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA 61 ++ + G A++TG G+G + A+ QGA L + + A LG + Sbjct: 19 PGSMFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVF 78 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 AN++ K ++ +A+ + ID+ VN AGI + +D+ V+ VN Sbjct: 79 SANLSDRKSIKQLAEVAEREMEGIDILVNNAGIT------RDGLFVRMQDQDWDDVLAVN 132 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L + R + M + + G IIN S+ G GQ Y A+K G++G + Sbjct: 133 LTAASTLTRELIHSMMRR------RYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKA 186 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 +A+++A I V IAPG + + L +K + + + +P R+G E A + Sbjct: 187 LAQEIASRNITVNCIAPGFIKSAMTDKLNEKQKEAIMAMIPM-KRMGIGEEIAFATVYLA 245 Query: 242 EN--PFLNGEVIRLDGAIRM 259 + +L G+ + ++G + M Sbjct: 246 SDEAAYLTGQTLHINGGMAM 265 >4BO1-A nrPDB Length = 269 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 73/259 (28%), Positives = 119/259 (45%), Gaps = 18/259 (6%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI---FAPA 63 S++G VA++TG + G+G + A L GA + S E A+ L N + Sbjct: 24 SLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL 83 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V+S++ V A L ++ G+ + VN AGI K ++ + V+N NL Sbjct: 84 DVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDE------WFDVVNTNLN 137 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + + V M + + G IIN SV G GQ Y+A+K G+ G T +A Sbjct: 138 SLYRLSKAVLRGMTK------ARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALA 191 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 R++ I V +APG T + LP+ R L Q+P RLG E A +V + + Sbjct: 192 REVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPL-GRLGQAEEIAKVVGFLASD 250 Query: 244 --PFLNGEVIRLDGAIRMQ 260 ++ G + ++G + M Sbjct: 251 GAAYVTGATVPVNGGMYMS 269 >1GEE-A nrPDB Length = 261 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 78/264 (29%), Positives = 126/264 (47%), Gaps = 20/264 (7%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIFA 61 + ++G V VITG ++GLG S A R + A V+ + E KK+GG I Sbjct: 3 KDLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAV 62 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 +VT E +V + A ++FG++DV +N AG+ + ++ +L D+ +VI+ N Sbjct: 63 KGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHE------MSLSDWNKVIDTN 116 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L G F R +N+ +G +IN +SV Y+ASKGG+ MT Sbjct: 117 LTGAFLGSREAIKYFVENDI-----KGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTET 171 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTT--LPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 +A + AP GIRV I PG TP+ + R + S +P +G+P E A + Sbjct: 172 LALEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPM-GYIGEPEEIAAVAAW 230 Query: 240 VIEN--PFLNGEVIRLDGAIRMQP 261 + + ++ G + DG + + P Sbjct: 231 LASSEASYVTGITLFADGGMTLYP 254 >4M8S-A nrPDB Length = 248 Score = 242 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 67/261 (25%), Positives = 119/261 (45%), Gaps = 20/261 (7%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL---GGNCIF 60 + + + G +A++TG + G+G + A L GA + S +++L GG Sbjct: 2 STQDLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRV 61 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 N + V+ + ++ FG++D+ VN AGI K+ E++ ++ V Sbjct: 62 L--NSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKE------EEWDDIMQV 113 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL F + V M + + G IIN SV G GQ Y+A+K G++G + Sbjct: 114 NLKSVFRASKAVLRGMMKQ------RAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSK 167 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 +AR++ GI V +APG T + LP++ R +Q R GD + A V + Sbjct: 168 SMAREVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTAL-GRFGDAQDIADAVLFL 226 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + ++ G+ + ++G + M Sbjct: 227 ASDQAKYITGQTLHVNGGMLM 247 >5ITV-A nrPDB Length = 255 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 78/265 (29%), Positives = 121/265 (45%), Gaps = 24/265 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-KKLGGNCIFAPANV 65 ++ +ITGGASG+G + + +GQ A V+ D+ ++GE K+ F ++ Sbjct: 4 NLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDI 63 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 T E Q A+ A FG +DV +N AGI + + L D+ +V+ VNL G Sbjct: 64 TDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHE------MELSDWNKVLQVNLTGM 117 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + M +G IINT SV AY+ASKGG++ +T +A D Sbjct: 118 FLMSKHALKHMLA------AGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVD 171 Query: 186 LAPIGIRVVTIAPGLFATPLLTT--------LPDKVRNFLASQVPFPSRLGDPAEYAHLV 237 A IRV + PG+ TPL ++++ A P RLG P E A+++ Sbjct: 172 YAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLL-RLGKPEEIANVM 230 Query: 238 QMVIEN--PFLNGEVIRLDGAIRMQ 260 + + ++ G I DG Q Sbjct: 231 LFLASDLSSYMTGSAITADGGYTAQ 255 >3AUT-A nrPDB Length = 269 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 77/263 (29%), Positives = 124/263 (47%), Gaps = 20/263 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSE----GETEAKKLGGNCIFAP 62 +K V VITGG++GLG + A R + A V+ N E + E ++ GG I Sbjct: 12 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 71 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +VT E++V + A ++FG +DV +N AG+ + ++ +L+++ +VI+ NL Sbjct: 72 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHE------LSLDNWNKVIDTNL 125 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G F R +N+ +G +IN +SV Y+ASKGG+ MT + Sbjct: 126 TGAFLGSREAIKYFVENDI-----KGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETL 180 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTT--LPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 A + AP GIRV I PG TP+ R + S +P +G P E A + + Sbjct: 181 ALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPM-GYIGKPEEVAAVAAFL 239 Query: 241 IEN--PFLNGEVIRLDGAIRMQP 261 + ++ G + DG + P Sbjct: 240 ASSQASYVTGITLFADGGMTKYP 262 >4NBT-A nrPDB Length = 240 Score = 240 bits (613), Expect = 4e-64, Method: Composition-based stats. Identities = 84/259 (32%), Positives = 132/259 (50%), Gaps = 23/259 (8%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++ ++G VAVITGGA GLG + A +GA + D+ G+ ++ N Sbjct: 1 MKKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDL----GDLTYSHPNVEGMYL--N 54 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VT V+ +K+G+ID+ VN AGI + + T + VI+VNL G Sbjct: 55 VTDVTGVEKFYQSVIDKYGKIDILVNNAGIT------KDAMTRKMTEAQWDAVIDVNLKG 108 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 FN+ RLV M N G IIN +SV G +GQA Y+A+K G++G+T+ A+ Sbjct: 109 VFNLTRLVGPQMQTN------GYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAK 162 Query: 185 DLAPIG--IRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 + A G +RV IAPG T +L T+P + + A+ +RLG P E A + + Sbjct: 163 EFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAALT-MLNRLGQPEEIAKVALFLAS 221 Query: 243 N--PFLNGEVIRLDGAIRM 259 + ++ G+ I ++G +R+ Sbjct: 222 DDASYVTGQTINVNGGMRL 240 >4CQL-A nrPDB Length = 261 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 85/273 (31%), Positives = 136/273 (49%), Gaps = 26/273 (9%) Query: 1 MAAAVR-SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG--- 56 MA+ ++ ++ +A++TG SG+G + + RL G+GAT D+ + + + LGG Sbjct: 1 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS 60 Query: 57 -------NCIFAPANVTSEKEVQAALTLAKEKFGRI-DVAVNCAGIAVAIKTYHEKKNQV 108 N A+V+ + + L + F R V V+CAGI H Sbjct: 61 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLH------ 114 Query: 109 HTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAY 168 + +D+ +VI VNL GTF V + A + N G RG IIN +S+ G VGQ Y Sbjct: 115 MSEDDWDKVIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTNY 169 Query: 169 SASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLG 228 +ASK G++G+T AR+L GIR ++ PG ATP+ +P KV + + +P LG Sbjct: 170 AASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLG 228 Query: 229 DPAEYAHLVQMVIE--NPFLNGEVIRLDGAIRM 259 DP + A +V + + ++ G + + G + M Sbjct: 229 DPEDVADVVAFLASEDSGYITGTSVEVTGGLFM 261 >3EZL-A nrPDB Length = 256 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 19/256 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS----EGETEAKKLGGNCIFAPANVT 66 +A +TGG G+G S +RL G V PNS + + K LG + + NV Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVG 73 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + A K + G IDV VN AGI + + T ED+Q VI+ NL F Sbjct: 74 DWDSTKQAFDKVKAEVGEIDVLVNNAGIT------RDVVFRKMTREDWQAVIDTNLTSLF 127 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV + V M + G IIN +SV +GQ GQ YS +K GI G T+ +A+++ Sbjct: 128 NVTKQVIDGMVER------GWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEV 181 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NP 244 A G+ V T++PG T ++ + V + + +P RLG P E +V + + Sbjct: 182 ATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPV-RRLGSPDEIGSIVAWLASEESG 240 Query: 245 FLNGEVIRLDGAIRMQ 260 F G L+G + M Sbjct: 241 FSTGADFSLNGGLHMG 256 >4K6F-A nrPDB Length = 255 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 77/257 (29%), Positives = 117/257 (45%), Gaps = 20/257 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIFAPANVT 66 +AV+TGG GLG + + RL G V+ PN+ G TE G P +V Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVA 71 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 Q + G +D+ VN AGI + + ++ VI NL F Sbjct: 72 DHDSCQQCIEKIVRDVGPVDILVNNAGIT------RDMTLRKLDKVNWDAVIRTNLDSVF 125 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N+ + V M + G I+N +SV +G VGQ Y+A+K G+ G T +A ++ Sbjct: 126 NMTKPVCDGMVER------GWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEI 179 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRN-FLASQVPFPSRLGDPAEYAHLVQMVIE--N 243 A G+ V T++PG AT ++T +P + + + Q+P RLG P E A LV + Sbjct: 180 ARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIP-AGRLGKPEEVAALVAYLCSEEA 238 Query: 244 PFLNGEVIRLDGAIRMQ 260 F+ G I ++G M Sbjct: 239 GFVTGSNIAINGGQHMH 255 >2PH3-A nrPDB Length = 245 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 108/255 (42%), Gaps = 20/255 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN-----CIFAPANV 65 A+ITG + G+G + A RL G + N E E + AN+ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + A + A E G +D VN AGI K ED++ V+ NL Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKD------EDWEAVLEANLSAV 115 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F R +M + + G I+N SV G GQA Y ASK G++G T +A++ Sbjct: 116 FRTTREAVKLMMK------ARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKE 169 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--N 243 A GI V +APG T + LP +V+ Q+P R G P E A V ++ Sbjct: 170 YAQRGITVNAVAPGFIETEMTERLPQEVKEAYLKQIP-AGRFGRPEEVAEAVAFLVSEKA 228 Query: 244 PFLNGEVIRLDGAIR 258 ++ G+ + +DG + Sbjct: 229 GYITGQTLCVDGGLT 243 >4KMS-A nrPDB Length = 249 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 86/263 (32%), Positives = 129/263 (49%), Gaps = 19/263 (7%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 MA +A++TGG G+G +TA L +G T V N + E ++ G I Sbjct: 1 MAHHHHHHMSEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYG--IK 58 Query: 61 APA-NVTSEKEVQAALTLAKEKFGR-IDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 NV +E + A+ +E+F + + + VN AGI +K + +D+ VI Sbjct: 59 TKCWNVADFEECRQAVKEIEEEFKKPVSILVNNAGIT------KDKMLHRMSHQDWNDVI 112 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 NVNL FN+ V M + G I+N +S+ A GQVGQ YSA+K GI+G Sbjct: 113 NVNLNSCFNMSSSVMEQMRNQD------YGRIVNISSINAQAGQVGQTNYSAAKAGIIGF 166 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 T +AR+ A I V IAPG AT ++ +P+ V + + +P RLG P E A V Sbjct: 167 TKALARETASKNITVNCIAPGYIATEMVGAVPEDVLAKIINSIP-KKRLGQPEEIARAVA 225 Query: 239 MVIE--NPFLNGEVIRLDGAIRM 259 +++ F+ GE I ++G M Sbjct: 226 FLVDENAGFITGETISINGGHNM 248 >4DMM-A nrPDB Length = 269 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 82/259 (31%), Positives = 129/259 (49%), Gaps = 23/259 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA----PA 63 + +A++TG + G+G + A L GA + ++ E A Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKA 85 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V+ E EV+A E++GR+DV VN AGI K++ D+Q V+++NL Sbjct: 86 DVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRD------DWQSVLDLNLG 139 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F R A +M + + G IIN ASV G GQA YSA+K G++G+T +A Sbjct: 140 GVFLCSRAAAKIMLKQ------RSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVA 193 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 ++LA GI V +APG AT + + L + L +P R G+ AE A +V+ + + Sbjct: 194 KELASRGITVNAVAPGFIATDMTSELAAE---KLLEVIPL-GRYGEAAEVAGVVRFLAAD 249 Query: 244 P---FLNGEVIRLDGAIRM 259 P ++ G+VI +DG + M Sbjct: 250 PAAAYITGQVINIDGGLVM 268 >4RZH-A nrPDB Length = 247 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 85/263 (32%), Positives = 127/263 (48%), Gaps = 23/263 (8%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIF 60 + ++ VA++TG + G+G +TA L G V+ +S E GG I Sbjct: 1 MTALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIA 60 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 ANV + EV + +KF RIDV VN AGI K LED+Q VI++ Sbjct: 61 VQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMK------LEDWQAVIDL 114 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL G F + V+ +M + + G IIN SVA G GQA YSA+K G++G T Sbjct: 115 NLTGVFLCTKAVSKLMLKQ------KSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTK 168 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 +A++LA G+ V +APG AT + L + + +P R G P E A ++ + Sbjct: 169 TVAKELASRGVTVNAVAPGFIATDMTENLNAEP---ILQFIPLA-RYGQPEEVAGTIRFL 224 Query: 241 IENP---FLNGEVIRLDGAIRMQ 260 +P ++ G+ +DG + M Sbjct: 225 ATDPAAAYITGQTFNVDGGMVMF 247 >4IIN-A nrPDB Length = 271 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 69/263 (26%), Positives = 114/263 (43%), Gaps = 19/263 (7%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNC 58 + G +ITG + G+G AK L G + N+E E ++ G Sbjct: 22 SNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKA 81 Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 + SE + A+ + G + VN AG+ +K EDF VI Sbjct: 82 AVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVV------RDKLAIKMKTEDFHHVI 135 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 + NL F R VM ++ + G ++N AS+ G +GQ YSASKGG++ M Sbjct: 136 DNNLTSAFIGCREALKVMSKS------RFGSVVNVASIIGERGNMGQTNYSASKGGMIAM 189 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 + A + A IR ++ PG T + L D+++ +P +RLG E A V Sbjct: 190 SKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPL-NRLGSAKEVAEAVA 248 Query: 239 MVIEN--PFLNGEVIRLDGAIRM 259 ++ + ++ GE ++++G + M Sbjct: 249 FLLSDHSSYITGETLKVNGGLYM 271 >2CDH-G nrPDB Length = 244 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 120/255 (47%), Gaps = 20/255 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA----KKLGGNCIFAPANVTS 67 V V+TG + G+G + A L G ++ +++ E + GG I +V+ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 E +V+A + A + +G IDV VN AGI KK+Q + VI++NL G F Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQ------WDEVIDLNLTGVFL 116 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + +M + ++G IIN ASV G +GQA Y+A+K G++G + AR+ A Sbjct: 117 CTQAATKIMMKK------RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGA 170 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI---ENP 244 I V + PG A+ + L + + + +P R G P A LV+ + Sbjct: 171 SRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPL-GRTGQPENVAGLVEFLALSPAAS 229 Query: 245 FLNGEVIRLDGAIRM 259 ++ G+ +DG I + Sbjct: 230 YITGQAFTIDGGIAI 244 >2NM0-A nrPDB Length = 253 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 23/257 (8%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANV 65 RS ++TGG G+GL+ A+ G + + + ++ Sbjct: 17 RSHMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRS--------GEPPEGFLAVKCDI 68 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 T ++V+ A +E G ++V + AG+ + EDF V+ NL GT Sbjct: 69 TDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMR------MSEEDFTSVVETNLTGT 122 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F V++ M + ++G ++ +SV G GQA Y+ASK G+VG +AR+ Sbjct: 123 FRVVKRANRAMLR------AKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARE 176 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN-- 243 L I +APG T + L D+ R + SQVP R P E A V+ + + Sbjct: 177 LGSRNITFNVVAPGFVDTDMTKVLTDEQRANIVSQVPL-GRYARPEEIAATVRFLASDDA 235 Query: 244 PFLNGEVIRLDGAIRMQ 260 ++ G VI +DG + M Sbjct: 236 SYITGAVIPVDGGLGMG 252 >3VZS-A nrPDB Length = 257 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 75/256 (29%), Positives = 118/256 (46%), Gaps = 19/256 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN----SEGETEAKKLGGNCIFAPANVT 66 +A +TGG G+G + +RL G V PN + + K LG + I + NV Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + A K + G +DV +N AGI + + T D+ VI+ NL F Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGIT------RDVVFRKMTRADWDAVIDTNLTSLF 128 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV + V M G I+N +SV +GQ GQ YS +K G+ G T+ +A+++ Sbjct: 129 NVTKQVIDGMADR------GWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEV 182 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NP 244 A G+ V T++PG AT ++ + V + + + +P RLG P E A + + + Sbjct: 183 ATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPV-KRLGLPEEIASICAWLSSEESG 241 Query: 245 FLNGEVIRLDGAIRMQ 260 F G L+G + M Sbjct: 242 FSTGADFSLNGGLHMG 257 >4NBV-A nrPDB Length = 246 Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 89/257 (34%), Positives = 129/257 (50%), Gaps = 18/257 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLGGNCIFAPAN 64 ++G VA+ITG A+G+G +TA+R GA VL DV + E G + Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRVD 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VT EV A + R+D+ VN AGI + + T F VI+VNL G Sbjct: 63 VTRRDEVDAMVAAVLAAHQRVDILVNNAGIT------KDARLAKMTEAQFDAVIDVNLKG 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 FN + VAG+M + +GVI+N +SV G GQ Y+ASK G++G T AR Sbjct: 117 VFNCAQAVAGLMTEQ------GKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWAR 170 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN- 243 +L P G+RV + PG T +L T+PDKV + + S + RL +PAE A + + + Sbjct: 171 ELGPKGVRVNAVCPGFVNTEILQTVPDKVLDGMTSSC-WLRRLAEPAEIASIYAFLASDD 229 Query: 244 -PFLNGEVIRLDGAIRM 259 ++NG I G + + Sbjct: 230 ASYVNGVAIEASGGMSL 246 >3O4R-A nrPDB Length = 261 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 111/255 (43%), Gaps = 17/255 (6%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA---PAN 64 + VA++T G+G + A+RL GA V+ + L G + + Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V ++ + + A + G ID+ V+ A + + + T E + + +++N+ Sbjct: 73 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDV-----TEEVWDKTLDINVKA 127 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + + V M + G ++ +S+AAF G + Y+ SK ++G+T +A Sbjct: 128 PALMTKAVVPEMEKR------GGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 181 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTL-PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE- 242 +LAP IRV +APGL T L DK + + RLG+P + A +V + Sbjct: 182 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 241 Query: 243 -NPFLNGEVIRLDGA 256 ++ GE + + G Sbjct: 242 DASYITGETVVVGGG 256 >4CQM-B nrPDB Length = 244 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 71/251 (28%), Positives = 120/251 (47%), Gaps = 16/251 (6%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 V + GG+ G+G + A+ + +G ++ + A LGG+ + +V E Sbjct: 8 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKE 67 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +VQ ++ GR++ VN AGI K ED ++ NL+G+ Sbjct: 68 HDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKT------EDMVSQLHTNLLGSMLT 121 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 + M Q Q G I+N S+ +G GQ+ YSASKGG+VG + +A+++A Sbjct: 122 CKAAMRTMIQQ------QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVAR 175 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNG 248 IRV +APG T + L ++ L +P R G+ E AH V ++E+P++ G Sbjct: 176 KKIRVNVVAPGFVHTDMTKDLKEE---HLKKNIPL-GRFGETIEVAHAVVFLLESPYITG 231 Query: 249 EVIRLDGAIRM 259 V+ +DG +++ Sbjct: 232 HVLVVDGGLQL 242 >3OEC-A nrPDB Length = 317 Score = 230 bits (586), Expect = 7e-61, Method: Composition-based stats. Identities = 72/287 (25%), Positives = 123/287 (42%), Gaps = 46/287 (16%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN---------------SEG 47 A + ++G VA ITG A G G + A RL GA V +D+ E Sbjct: 39 ARMNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKET 98 Query: 48 ETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQ 107 ++ G I A+V +QA + A +FG ID+ V+ GI+ ++ + Sbjct: 99 VRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGIS------NQGEVV 152 Query: 108 VHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA 167 T + + ++ NLIG ++ R V M + GQ G +I +S G GQ+ Sbjct: 153 SLTDQQWSDILQTNLIGAWHACRAVLPSMIER-----GQGGSVIFVSSTVGLRGAPGQSH 207 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSR- 226 Y+ASK G+ G+ L +A ++ IRV ++ PG T + L +K+ + P+R Sbjct: 208 YAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVNTEM--ALNEKLLKMFLPHLENPTRE 265 Query: 227 ---------------LGDPAEYAHLVQMVIEN--PFLNGEVIRLDGA 256 +P + ++ V + + +++G I +DG Sbjct: 266 DAAELFSQLTLLPIPWVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >6NRP-A nrPDB Length = 263 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 66/253 (26%), Positives = 114/253 (45%), Gaps = 21/253 (8%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAPANVT 66 ++TG + G+G + A +L G + E + LG N + +V Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + VQ L E+ G V AG+ H+ T +D+ VI+ +L G + Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLT------HDGAFPALTDQDWDEVISTSLDGFY 138 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV++ + M + G I+ +SV+ G GQ YSA+K G++G T +A +L Sbjct: 139 NVLKPLIMPMI-----HLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALEL 193 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--P 244 A I V +APGL T ++T D+V+ +P R+G E A +V+ + + Sbjct: 194 AKRKITVNCVAPGLIETEMVT---DEVKEHALKMIPL-QRMGQVDEVASVVKFLCSDEAS 249 Query: 245 FLNGEVIRLDGAI 257 ++ +VI ++G + Sbjct: 250 YVTRQVISVNGGL 262 >2ZAT-A nrPDB Length = 260 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 61/257 (23%), Positives = 112/257 (43%), Gaps = 17/257 (6%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA---P 62 + ++ VA++T G+GL+ A+RL GA V+ + L G + Sbjct: 10 KPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTV 69 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V ++ + + +A G +D+ V+ A + + T E + ++++VN+ Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDA-----TEEVWDKILHVNV 124 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 T + + V M + G ++ +SV A+ Y+ SK ++G+T + Sbjct: 125 KATVLMTKAVVPEMEKR------GGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNL 178 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTL-PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 A +LAP IRV +APGL T L DK R + RLG+P + A +V + Sbjct: 179 AVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLC 238 Query: 242 E--NPFLNGEVIRLDGA 256 ++ GE + + G Sbjct: 239 SEDASYITGETVVVGGG 255 >1GEG-A nrPDB Length = 256 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 72/262 (27%), Positives = 116/262 (44%), Gaps = 26/262 (9%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPANVTS 67 VA++TG G+G + A RLV G + D ++ + E + GG+ + +V+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 +V AA+ A++ G DV VN AG+A + + T E +V N+N+ G Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTP------IESITPEIVDKVYNINVKGVIW 116 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ + G G IIN S A G A YS+SK + G+T ARDLA Sbjct: 117 GIQAAVEAFKKE-----GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLA 171 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLAS----------QVPFPSRLGDPAEYAHLV 237 P+GI V PG+ TP+ + +V + RL +P + A V Sbjct: 172 PLGITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACV 231 Query: 238 QMVIE--NPFLNGEVIRLDGAI 257 + + ++ G+ + +DG + Sbjct: 232 SYLASPDSDYMTGQSLLIDGGM 253 >1AE1-A nrPDB Length = 273 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 67/265 (25%), Positives = 123/265 (46%), Gaps = 27/265 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPA 63 S+KG A++TGG+ G+G + + L G GA E + ++ G N + Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVC 77 Query: 64 NVTSEKEVQAALTLAKEKF-GRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 ++ S E + F G++++ VN AG+ + K+ + T +D+ ++ N Sbjct: 78 DLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVI------HKEAKDFTEKDYNIIMGTNF 131 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +++ ++ ++ + Q G +I +S+A F + YSASKG I MT + Sbjct: 132 EAAYHLSQIAYPLL------KASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSL 185 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTL-------PDKVRNFLASQVPFPSRLGDPAEYAH 235 A + A IRV ++APG+ TPL+ T +++ NF+ + P R G P E + Sbjct: 186 ACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIV-KTPM-GRAGKPQEVSA 243 Query: 236 LVQMVI--ENPFLNGEVIRLDGAIR 258 L+ + ++ G++I DG Sbjct: 244 LIAFLCFPAASYITGQIIWADGGFT 268 >5VT6-A nrPDB Length = 269 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 20/257 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE----AKKLGGNCIFAPANVT 66 VA +TGG GLG + ++RL G + ++ + + G + +V Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVA 85 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + + FG++DV +N AGI + T D+ V+ +L F Sbjct: 86 DFESCERCAEKVLADFGKVDVLINNAGIT------RDATFMKMTKGDWDAVMRTDLDAMF 139 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 NV + M + + G I+N SV G GQA Y+++K GI G T +A + Sbjct: 140 NVTKQFIAGMVER------RFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALET 193 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRN-FLASQVPFPSRLGDPAEYAHLVQMVIENP- 244 A GI V T++PG AT ++ +P V + Q+P RLG P E A L+ + + Sbjct: 194 AKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPV-GRLGRPDEVAALIAFLCSDDA 252 Query: 245 -FLNGEVIRLDGAIRMQ 260 F+ G + ++G + M Sbjct: 253 GFVTGADLAINGGMHMS 269 >1NFF-A nrPDB Length = 260 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 78/252 (30%), Positives = 124/252 (49%), Gaps = 20/252 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + G VA+++GGA G+G S + +V +GA V D+ + EG+ A +L + +VT Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVT 63 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + +AA+ A FG + V VN AGI + + + L ++QR+++VNL G F Sbjct: 64 QPAQWKAAVDTAVTAFGGLHVLVNNAGI------LNIGTIEDYALTEWQRILDVNLTGVF 117 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 IR V M + RG IIN +S+ G V Y+A+K + G+T A +L Sbjct: 118 LGIRAVVKPMKE------AGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALEL 171 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--P 244 P GIRV +I PGL TP+ +P+ + R +P E ++LV + + Sbjct: 172 GPSGIRVNSIHPGLVKTPMTDWVPEDIFQTAL------GRAAEPVEVSNLVVYLASDESS 225 Query: 245 FLNGEVIRLDGA 256 + G +DG Sbjct: 226 YSTGAEFVVDGG 237 >2EW8-A nrPDB Length = 249 Score = 226 bits (576), Expect = 8e-60, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 108/260 (41%), Gaps = 22/260 (8%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV-PNSEGETEAKKLGGNCIFAPA 63 + +K +AVITGGA+G+G + A+R +GA + D+ P E E + LG + Sbjct: 2 TQRLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKC 61 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V+ +V+A FGR D+ VN AGI I T E +++ +N+ Sbjct: 62 DVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIP------FDELTFEQWKKTFEINVD 115 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F + + M +N G IIN S + Y ++K +G T +A Sbjct: 116 SGFLMAKAFVPGMKRN------GWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALA 169 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTT----LPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 DL GI V IAP L T V + +P RL P + Sbjct: 170 SDLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP---RLQVPLDLTGAAAF 226 Query: 240 VIEN--PFLNGEVIRLDGAI 257 + + F+ G+ + +DG + Sbjct: 227 LASDDASFITGQTLAVDGGM 246 >5OJG-A nrPDB Length = 260 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 72/268 (26%), Positives = 123/268 (45%), Gaps = 21/268 (7%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI- 59 M + R +G VA++T G+GL+ A+RL+ +GA+ V+ + + L + Sbjct: 1 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLT 60 Query: 60 ---FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 ++ S + + + +KFG+I++ VN GI A E +QV + + Sbjct: 61 KVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQV-----WDK 115 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 + VN+ F + +LV + + G II AS +A++ G AAY +K +V Sbjct: 116 LFEVNVKAGFQMTKLVHPHIAKE------GGGAIIFNASYSAYKSPPGIAAYGVTKTTLV 169 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLP----DKVRNFLASQVPFPSRLGDPAE 232 G+T +A LA IRV IAPG+ T + L D + Q RLG P + Sbjct: 170 GLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDD 229 Query: 233 YAHLVQMVIEN--PFLNGEVIRLDGAIR 258 A V + + ++ GE+I + G ++ Sbjct: 230 CAGTVAYLASDDSSYITGEMIIIAGGVQ 257 >5OVL-A nrPDB Length = 300 Score = 223 bits (568), Expect = 6e-59, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 107/252 (42%), Gaps = 23/252 (9%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 ++TGG G+GL+ A+RL G + + + +VT Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGS--------GAPDDLFGVQCDVTDSAA 120 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 V A +E G ++V V AGI+ T E F+ VIN NL G F + Sbjct: 121 VDRAFKEVEEHQGPVEVLVANAGISKDAFLMR------MTEERFEEVINTNLTGAFRCAQ 174 Query: 131 LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 + M + + G II SV+ G QA Y+A+K G++GM I+R+LA G Sbjct: 175 RASRTMQRK------RFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAG 228 Query: 191 IRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNG 248 + +APG T + L ++++ +P R+G E A V + ++ G Sbjct: 229 VTANVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAG 287 Query: 249 EVIRLDGAIRMQ 260 VI +DG + M Sbjct: 288 AVIPVDGGMGMG 299 >2AE2-A nrPDB Length = 260 Score = 223 bits (568), Expect = 7e-59, Method: Composition-based stats. Identities = 62/266 (23%), Positives = 124/266 (46%), Gaps = 24/266 (9%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCI 59 A +++G A++TGG+ G+G + L GA+ E T+ + G Sbjct: 2 AGRWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVE 61 Query: 60 FAPANVTSEKEVQAALTLAKEKF-GRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 + +++S E Q + F G++++ VN AGI + K+ + +T+ED+ ++ Sbjct: 62 ASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIY------KEAKDYTVEDYSLIM 115 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 ++N +++ L + + +RG ++ +SV+ +A Y A+KG + + Sbjct: 116 SINFEAAYHLSVLAHPFL------KASERGNVVFISSVSGALAVPYEAVYGATKGAMDQL 169 Query: 179 TLPIARDLAPIGIRVVTIAPGLFAT---PLLTTLPDKVR--NFLASQVPFPSRLGDPAEY 233 T +A + A IRV + PG+ AT + P++ N L + R+G+P E Sbjct: 170 TRCLAFEWAKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCAL-RRMGEPKEL 228 Query: 234 AHLVQMVI--ENPFLNGEVIRLDGAI 257 A +V + ++ G++I +DG + Sbjct: 229 AAMVAFLCFPAASYVTGQIIYVDGGL 254 >4RZI-B nrPDB Length = 240 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 119/254 (46%), Gaps = 23/254 (9%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 ++ V V+TGG G+G + K L GA D+ G TEA + ANVT Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEA-------LGVVANVTD 58 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + + AA +K G + V AGI + T D+ V+NVNL G Sbjct: 59 LESMTAAAAEITDKLGPVYGVVANAGIT------KDNFFPKLTPADWDAVLNVNLKGVAY 112 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ M + + G I+ +S++ G VGQ YSA+K G++GM +AR+ A Sbjct: 113 SIKPFIEGMYER------KAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGA 166 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE---NP 244 G+R +APG T + + + +R + ++PF R G P E A V ++ + Sbjct: 167 RYGVRANAVAPGFIDTEMTLAIREDIREKITKEIPF-RRFGKPEEIAWAVAFLLSPVASS 225 Query: 245 FLNGEVIRLDGAIR 258 ++ GEV+R++GA Sbjct: 226 YVTGEVLRVNGAHH 239 >4Z9Y-A nrPDB Length = 253 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 119/256 (46%), Gaps = 17/256 (6%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-AKKLGGNCIFAPANV 65 ++G VA+ITG +GLG A L G V +++ + E LG + A++ Sbjct: 7 DLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADM 66 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 ++ + A +FG +D+ VN AGI + + +++ V+N+N+ Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGI------IRREDAIEFSEKNWDDVMNLNIKSV 120 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + VA + G+ G IIN AS+ +F+G + +Y+ASK ++G+T +A + Sbjct: 121 FFMSQTVARQFIKQ-----GKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANE 175 Query: 186 LAPIGIRVVTIAPGLFATPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE- 242 A GI V IAPG AT L ++ + ++P R G P + + Sbjct: 176 WAKHGINVNAIAPGYMATNNTQQLRADEERSKEILDRIP-AGRWGLPQDLMGPSVFLASS 234 Query: 243 -NPFLNGEVIRLDGAI 257 + ++NG I +DG Sbjct: 235 ASDYINGYTIAVDGGW 250 >5T5Q-A nrPDB Length = 247 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 76/256 (29%), Positives = 121/256 (47%), Gaps = 20/256 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG--NCIFAPANV 65 + V+TG G+G + A+ GA VL D+ + A LG A+ Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADA 66 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 +S + + + LA E+FG ID V AGI Y K + D+ R I++NL G Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGI------YQAKPFAEMSDADWHRTISINLDGV 120 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + + + ++ I+ AS+AA+ G A Y A+KG +V MT ++R+ Sbjct: 121 FYLCKRALPALKEDS--------SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRE 172 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--N 243 LAP RV ++PG+ TP+ + L + +Q P RLG P+E A ++ + Sbjct: 173 LAPK-TRVNGVSPGIIETPMTSELLKTRMDETMTQTPL-KRLGKPSEIASVIAFLCSPAA 230 Query: 244 PFLNGEVIRLDGAIRM 259 F+ GE I+++G I M Sbjct: 231 SFVTGETIQVNGGIYM 246 >5U9P-A nrPDB Length = 265 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 75/259 (28%), Positives = 115/259 (44%), Gaps = 20/259 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL---GGNCIFAPA 63 + G A+ITG G+GL+ A+ L GA V+ D + T A++ G A Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF 76 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V +V+AA+ + + G ID+ VN AGI +D+ ++ VNL Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQ------RRAPLDAFEPDDWHALMRVNLD 130 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G FNV + VA M G IIN SV + + A Y+A+KG + +T + Sbjct: 131 GVFNVAQAVARHMIAR------GHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMC 184 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKV--RNFLASQVPFPSRLGDPAEYAHLVQMVI 241 D A GI+ +APG F T L L D ++L + P R G E + Sbjct: 185 ADWARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTP-AGRWGQVDELCGAAIFLA 243 Query: 242 E--NPFLNGEVIRLDGAIR 258 + F+NG+ + +DG + Sbjct: 244 SAASDFVNGQTLFVDGGLT 262 >5OVJ-A nrPDB Length = 256 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 107/252 (42%), Gaps = 23/252 (9%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 ++TGG G+GL+ A+RL G + + + +VT Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGS--------GAPDDLFGVQCDVTDSAA 76 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 V A +E G ++V V AGI+ T E F+ VIN NL G F + Sbjct: 77 VDRAFKEVEEHQGPVEVLVANAGISKDAFLMR------MTEERFEEVINTNLTGAFRCAQ 130 Query: 131 LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 + M + + G II SV+ G QA Y+A+K G++GM I+R+LA G Sbjct: 131 RASRTMQRK------RFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAG 184 Query: 191 IRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNG 248 + +APG T + L ++++ +P R+G E A V + ++ G Sbjct: 185 VTANVVAPGYIDTEMTRALDERIQAGALDFIP-AKRVGTAEEVAGAVSFLASEDASYIAG 243 Query: 249 EVIRLDGAIRMQ 260 VI +DG + M Sbjct: 244 AVIPVDGGMGMG 255 >4IIV-A nrPDB Length = 267 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 112/255 (43%), Gaps = 19/255 (7%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPAN 64 ++TG + G+G + A++L G + ++ G E GGN + Sbjct: 25 MSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFD 84 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V + ++ + L + G V+ AGIA + + +D+ VI+ NL Sbjct: 85 VANREQCREVLEHEIAQHGAWYGVVSNAGIA------RDAAFPALSNDDWDAVIHTNLDS 138 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 +NVI+ M Q G II +SV+ G GQ YSA+K GI+G T +A Sbjct: 139 FYNVIQPCIMPMIGAR-----QGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAI 193 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN- 243 +LA I V IAPGL T ++ + + S +P R+G E A L ++ + Sbjct: 194 ELAKRKITVNCIAPGLIDTGMIE-MEESALKEAMSMIPM-KRMGQAEEVAGLASYLMSDI 251 Query: 244 -PFLNGEVIRLDGAI 257 ++ +VI ++G + Sbjct: 252 AGYVTRQVISINGGM 266 >3PPI-A nrPDB Length = 281 Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 102/257 (39%), Positives = 155/257 (60%), Gaps = 1/257 (0%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++ +G A+++GGA GLG +T +RL G V+ D+ +G+ A +LG F N Sbjct: 25 IKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTN 84 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VTSE V AA+ A + GR+ AV G + ++ + F + I++ L G Sbjct: 85 VTSEDSVLAAIEAAN-QLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNG 143 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T+NV RLVA + EP + G+RG ++ TAS+A +EGQ+GQ AY+A+K G++G+T+ AR Sbjct: 144 TYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAAR 203 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP 244 DL+ GIRV TIAPG TP++ ++ ++ A+ +PFP RLG P E+A ++ N Sbjct: 204 DLSSAGIRVNTIAPGTMKTPIMESVGEEALAKFAANIPFPKRLGTPDEFADAAAFLLTNG 263 Query: 245 FLNGEVIRLDGAIRMQP 261 ++NGEV+RLDGA R P Sbjct: 264 YINGEVMRLDGAQRFTP 280 >6CI9-A nrPDB Length = 259 Score = 216 bits (550), Expect = 8e-57, Method: Composition-based stats. Identities = 58/259 (22%), Positives = 109/259 (42%), Gaps = 19/259 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG---NCIFAPA 63 S++G A++TGG+ G+G A+ G V+ + + L G A Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRA 65 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +VT ++ + + + G +D+ AGI + + + T +D ++V+ VN Sbjct: 66 DVTDPEDARRTVAETVSRHGGLDIVCANAGI------FPSGRLEDLTPDDIEQVLGVNFK 119 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPI 182 GT +++ + + G ++ T+S+ G G + Y ASK +G Sbjct: 120 GTVYIVQAALQALTAS------GHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTA 173 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI- 241 A +LAP I + + PG T L + + +AS +P RLG A+ + Sbjct: 174 AMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIP-AGRLGSVADIGNAALFFAT 232 Query: 242 -ENPFLNGEVIRLDGAIRM 259 E ++ G+ + +DG + Sbjct: 233 DEAAYVTGQTLVVDGGQVL 251 >3RWB-A nrPDB Length = 247 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 110/255 (43%), Gaps = 13/255 (5%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 + G A++TG A G+G + A RL GAT ++ D+ + A +G A+ Sbjct: 1 TERLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAAD 60 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 ++ V+A + G ID+ VN A I + L+ ++++I+VNL G Sbjct: 61 ISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDD------VDLDHWRKIIDVNLTG 114 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 TF V R M G+ G +I+ AS F G AAY A+KGG++G T +A Sbjct: 115 TFIVTRAGTDQM-----RAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALAT 169 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP 244 +L I + PGL + + P + G P A +V + + Sbjct: 170 ELGKYNITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDD 229 Query: 245 --FLNGEVIRLDGAI 257 ++ G+ + +D + Sbjct: 230 ARWITGQTLNVDAGM 244 >1YXM-A nrPDB Length = 303 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 62/267 (23%), Positives = 115/267 (43%), Gaps = 28/267 (10%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN--------CI 59 ++G VA++TGGA+G+G + K L+ G+ V+ ++ A +L N I Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 N+ +E+EV + + FG+I+ VN G H + + + V+ Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEH------ISSKGWHAVLE 129 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL GTF + + V + G I+N V G A++ G+ +T Sbjct: 130 TNLTGTFYMCKAVYSSWMKEH------GGSIVNII-VPTKAGFPLAVHSGAARAGVYNLT 182 Query: 180 LPIARDLAPIGIRVVTIAPGLFAT-PLLTTLPDKVRNFLA---SQVPFPSRLGDPAEYAH 235 +A + A GIR+ +APG+ + + ++F ++P R+G P E + Sbjct: 183 KSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIP-AKRIGVPEEVSS 241 Query: 236 LVQMVIE--NPFLNGEVIRLDGAIRMQ 260 +V ++ F+ G+ + +DG + Sbjct: 242 VVCFLLSPAASFITGQSVDVDGGRSLY 268 >3WTC-A nrPDB Length = 262 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 65/272 (23%), Positives = 124/272 (45%), Gaps = 26/272 (9%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKK---LGGNCIF 60 + S+ G +A +TG A G+G + A RL GA +LLDV AK+ LG + Sbjct: 2 SHMSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVA 61 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 A++++ + ++ L A + G +D+ VN AGI + ++ +++ ++ Sbjct: 62 LTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEI------EKIFSI 115 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 N+ G ++ A + + G +G IIN S+A EG AYSA+K + +T Sbjct: 116 NVQGVLWGMQAAATLFKEK-----GTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQ 170 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV----------PFPSRLGDP 230 A++LA GI V + PG+ T + T+ ++ +++ R+ Sbjct: 171 SAAKELASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETA 230 Query: 231 AEYAHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 + A V + + ++ G+ + +DG + + Sbjct: 231 DDVAGFVAYLSSSDADYMTGQSVLIDGGLVFR 262 >1UZM-A nrPDB Length = 247 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 71/252 (28%), Positives = 115/252 (45%), Gaps = 23/252 (9%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 ++TGG G+GL+ A+RL G + + + +VT Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL--------FGVEVDVTDSDA 67 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 V A T +E G ++V V+ AG++ T E F++VIN NL G F V + Sbjct: 68 VDRAFTAVEEHQGPVEVLVSNAGLSADAFLMR------MTEEKFEKVINANLTGAFRVAQ 121 Query: 131 LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 + M +N + G +I SV+ G QA Y+ASK G++GM IAR+L+ Sbjct: 122 RASRSMQRN------KFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKAN 175 Query: 191 IRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNG 248 + +APG T + L ++++ +P R+G PAE A +V + +++G Sbjct: 176 VTANVVAPGYIDTDMTRALDERIQQGALQFIP-AKRVGTPAEVAGVVSFLASEDASYISG 234 Query: 249 EVIRLDGAIRMQ 260 VI +DG + M Sbjct: 235 AVIPVDGGMGMG 246 >4IS3-A nrPDB Length = 268 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 71/262 (27%), Positives = 121/262 (46%), Gaps = 20/262 (7%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG-----NC 58 + V+ V +ITGG G+G + AK + GA + E +T +L Sbjct: 19 GMNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEV 78 Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 + ++TS V AA+ +K+GR+DV +N AGI + E+F+ ++ Sbjct: 79 LGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITS------NNVFSRVSEEEFKHIM 132 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 ++N+ G FN M + ++GVIINTASV G + Y ASK ++G+ Sbjct: 133 DINVTGVFNGAWCAYQCM------KDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGL 186 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 T + R++ IRVV +APG+ T + P ++ +P R+ +P E A++ Sbjct: 187 THGLGREIIRKNIRVVGVAPGVVNTDMTNGNPPEIMEGYLKALPM-KRMLEPEEIANVYL 245 Query: 239 MVIEN--PFLNGEVIRLDGAIR 258 + + + + +DGA R Sbjct: 246 FLASDLASGITATTVSVDGAYR 267 >2Q2Q-A nrPDB Length = 255 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 75/265 (28%), Positives = 114/265 (43%), Gaps = 27/265 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSE-GETEAKKLGGNCIFAPANV 65 ++KG A++TG SG+GL A+ L GA VL + E + G + PA++ Sbjct: 1 TLKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADL 60 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + +++A LA+ +FG +D+ VN AGI H + LE + ++I +NL Sbjct: 61 SDVAQIEALFALAEREFGGVDILVNNAGIQ------HVAPVEQFPLESWDKIIALNLSAV 114 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F+ RL M G IIN ASV G G+AAY A+K G+VG+T + + Sbjct: 115 FHGTRLALPGMRARN------WGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLE 168 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDK-----------VRNFLASQVPFPSRLGDPAEYA 234 A + I PG TPL+ D + LA + P + P Sbjct: 169 TATSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLA-FVTPEHLG 227 Query: 235 HLVQMVIE--NPFLNGEVIRLDGAI 257 LV + + G +DG Sbjct: 228 ELVLFLCSEAGSQVRGAAWNVDGGW 252 >2HSD-A nrPDB Length = 253 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 126/258 (48%), Gaps = 15/258 (5%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANV 65 + G +ITGGA GLG A++ V GA VL DV + EG A++LG + +V Sbjct: 1 NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDV 60 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 T E++ Q + A+E+FG +D VN AGI+ + E ++E F++V+ +NL G Sbjct: 61 TIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETE------SVERFRKVVEINLTGV 114 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F ++ V M + G I+N +S A G ++Y ASK G+ G++ A + Sbjct: 115 FIGMKTVIPAM------KDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVE 168 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN-- 243 L IRV ++ PG+ TP+ + P R+G+P E A V ++ + Sbjct: 169 LGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPM-GRVGEPGEIAGAVVKLLSDTS 227 Query: 244 PFLNGEVIRLDGAIRMQP 261 ++ G + +DG P Sbjct: 228 SYVTGAELAVDGGWTTGP 245 >3V2G-A nrPDB Length = 271 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 113/257 (43%), Gaps = 23/257 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAP 62 S+ G A +TGG+ G+G + AKRL +GA L V +E E ++ GG + Sbjct: 28 SLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIR 87 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 A+ + ++ A+ E G +D+ VN AGI +H + T+ DF V+ VN Sbjct: 88 ADNRDAEAIEQAIRETVEALGGLDILVNSAGI------WHSAPLEETTVADFDEVMAVNF 141 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTAS-VAAFEGQVGQAAYSASKGGIVGMTLP 181 F IR + + G G II S +A G + YSASK + G+T Sbjct: 142 RAPFVAIRSASRHL--------GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKG 193 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 +ARDL P GI V + PG T + D + G+P + A LV + Sbjct: 194 LARDLGPRGITVNIVHPGSTDTDMNPADGDHAEAQ--RERIATGSYGEPQDIAGLVAWLA 251 Query: 242 --ENPFLNGEVIRLDGA 256 + F+ G + +DG Sbjct: 252 GPQGKFVTGASLTIDGG 268 >3WYE-A nrPDB Length = 256 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 72/262 (27%), Positives = 118/262 (45%), Gaps = 26/262 (9%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPANVTS 67 VA++TG G+G + A RLV G + D ++ + E + GG+ + +V+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 +V AA+ A++ G DV VN AGIA T ED +++ +VN+ F Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLE------VTEEDLKQIYSVNVFSVFF 116 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 I+ + G G IIN AS+AA +G +AYS +K + G+T ARDLA Sbjct: 117 GIQAAVEAFKKE-----GHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLA 171 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV----------PFPSRLGDPAEYAHLV 237 P+GI V PG+ T + + ++ + R P + A LV Sbjct: 172 PLGITVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLV 231 Query: 238 QMVIE--NPFLNGEVIRLDGAI 257 + + ++ G+ + +DG + Sbjct: 232 SFLASPDSDYMTGQSLLIDGGM 253 >3R3S-A nrPDB Length = 294 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 62/263 (23%), Positives = 112/263 (42%), Gaps = 23/263 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-----AKKLGGNCIFA 61 +K A++TGG SG+G + A +GA + +P E + + ++ G + Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 P +++ E ++ + A+E G +D+ AG AI + T E FQ+ VN Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKD-----LTSEQFQQTFAVN 160 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + F + + ++ + II T+S+ A++ Y+A+K I+ + Sbjct: 161 VFALFWITQEAIPLLPK--------GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRG 212 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRN--FLASQVPFPSRLGDPAEYAHLVQM 239 +A+ +A GIRV +APG T L + Q P R G PAE A + Sbjct: 213 LAKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPM-KRAGQPAELAPVYVY 271 Query: 240 VIE--NPFLNGEVIRLDGAIRMQ 260 + + ++ EV + G + Sbjct: 272 LASQESSYVTAEVHGVCGGEHLG 294 >2CFC-A nrPDB Length = 250 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 124/258 (48%), Gaps = 18/258 (6%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAK----KLGGNCIFAPAN 64 VA++TG +SG GL+ A R + +G LD+ E A+ + A+ Sbjct: 1 MSRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRAD 60 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V E +V AA+ E+FG IDV VN AGI + +E F +V+ VN+ G Sbjct: 61 VADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEA---GVLHTTPVEQFDKVMAVNVRG 117 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F R V M GVI+N ASVA+ G++AY+ SKG ++ +T +A Sbjct: 118 IFLGCRAVLPHMLLQ------GAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAV 171 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYAHLVQMVI- 241 D A GIR + PG+ TP+ D ++R+ + +++P +G A+ A V + Sbjct: 172 DYAGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIP-QKEIGTAAQVADAVMFLAG 230 Query: 242 -ENPFLNGEVIRLDGAIR 258 + ++NG + +DGA Sbjct: 231 EDATYVNGAALVMDGAYT 248 >2X9N-A nrPDB Length = 288 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 60/262 (22%), Positives = 107/262 (40%), Gaps = 17/262 (6%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-----ETEAKKLGGNCIFAPANVTS 67 AV+TG A +G + A +L G V+ ++E + K+ + A++T+ Sbjct: 26 AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTN 85 Query: 68 ----EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKT---YHEKKNQVHTLE-DFQRVIN 119 + + FGR DV VN A HE + T+E +I Sbjct: 86 SNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG 145 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 N I F + A P+ I+N + + + Y+ K +VG+T Sbjct: 146 TNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLT 205 Query: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 A +LAP GIRV +APG+ P+ + ++ ++ +VP R + A V Sbjct: 206 QSAALELAPYGIRVNGVAPGVSLLPV--AMGEEEKDKWRRKVPLGRREASAEQIADAVIF 263 Query: 240 VIENP--FLNGEVIRLDGAIRM 259 ++ ++ G +I++DG + + Sbjct: 264 LVSGSAQYITGSIIKVDGGLSL 285 >3UVE-A nrPDB Length = 286 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 68/289 (23%), Positives = 112/289 (38%), Gaps = 45/289 (15%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV-------------------PNSEG 47 V+G VA +TG A G G S A RL +GA + +D+ +E Sbjct: 8 RVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAET 67 Query: 48 ETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQ 107 K + A +V ++AA+ E+ GR+D+ V AGI T Sbjct: 68 ADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLD----- 122 Query: 108 VHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA 167 + ED+ +I++NL G + ++ M GG+ G II T+SV + Sbjct: 123 KTSEEDWTEMIDINLAGVWKTVKAGVPHMIA-----GGRGGSIILTSSVGGLKAYPHTGH 177 Query: 168 YSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTT-------LPDKVRNFLASQ 220 Y A+K G+VG+ +L IRV ++ P TP+L PD Sbjct: 178 YVAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDM 237 Query: 221 VP-------FPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 P P +P + ++ V + ++ G + +D ++ Sbjct: 238 APICQMFHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCLK 286 >3W8F-A nrPDB Length = 260 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 66/269 (24%), Positives = 104/269 (38%), Gaps = 30/269 (11%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSE-----GETEAKKLGGNCIFAP 62 +KG AV+TG SG+GL+ A L GA V+ E T K G + Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 A+++ + + + A E G +D+ VN AGI H + ++ + +I +NL Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQ------HTAPIEEFPVDKWNAIIALNL 115 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F+ +M + G IIN AS V ++AY A+K G+VG+T Sbjct: 116 SAVFHGTAAALPIMQKQ------GWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVT 169 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSR-----------LGDPA 231 A + A GI I PG TPL+ + + + +R P Sbjct: 170 ALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPE 229 Query: 232 EYAHLVQMV--IENPFLNGEVIRLDGAIR 258 + + + G + LDG Sbjct: 230 QLGGAAVFLSSAAADQMTGTTLSLDGGWT 258 >3T7C-A nrPDB Length = 299 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 68/284 (23%), Positives = 119/284 (41%), Gaps = 41/284 (14%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV-------------PNSEGET--EAK 52 V+G VA ITG A G G S A L +GA + +DV P+ ET + + Sbjct: 26 VEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVE 85 Query: 53 KLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLE 112 LG I + +V +QAA+ + GR+D+ + A +A + + Sbjct: 86 ALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNR-----MDPK 140 Query: 113 DFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASK 172 ++ +I+VNL G + R+ + G + G I+ T+S+ G Y ASK Sbjct: 141 TWRDMIDVNLNGAWITARVAIPHIMA-----GKRGGSIVFTSSIGGLRGAENIGNYIASK 195 Query: 173 GGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLP--------------DKVRNFLA 218 G+ G+ +A +L P IRV + P ATP+L P + + Sbjct: 196 HGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASR 255 Query: 219 SQVPFPSRLGDPAEYAHLVQMVIENP--FLNGEVIRLDGAIRMQ 260 P +PA+ ++ + ++ + ++ G + +DG ++ Sbjct: 256 QMHVLPIPYVEPADISNAILFLVSDDARYITGVSLPVDGGALLK 299 >4MOW-A nrPDB Length = 256 Score = 207 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 24/262 (9%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIF 60 + + G VA++TG + G+G + AK L +GA V+ + G + + GG + Sbjct: 9 MSKLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVA 68 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 +V+ + Q + A E +GR+DV VN +G+ Y + T E ++R + Sbjct: 69 VGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGV------YEFAPIEAITEEHYRRQFDT 122 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 N+ G + + G+ IIN +SV A YS +KG + +T Sbjct: 123 NVFGVLLTTQAAVKHL--------GEGASIINISSVVTSITPPASAVYSGTKGAVDAITG 174 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTT---LPDKVRNFLASQVPFPSRLGDPAEYAHLV 237 +A +L P IRV I PG+ T + + + + Q P RLG+P + A + Sbjct: 175 VLALELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPL-GRLGEPNDIASVA 233 Query: 238 QMVIENP--FLNGEVIRLDGAI 257 + + ++ GE + + G + Sbjct: 234 VFLASDDARWMTGEHLVVSGGL 255 >1AHH-A nrPDB Length = 255 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 115/256 (44%), Gaps = 20/256 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE---TEAKKLGGNCIFAPA 63 + G A+ITG +G+G A GA+ V+ D+ E ++LGG Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 ++TSE+E+ A A K G++D+ VN AG + DF+R +N+ Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-------FDMPMADFRRAYELNVF 120 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F++ +LVA M +N GVI+ S+AA + +Y++SK + +A Sbjct: 121 SFFHLSQLVAPEMEKN------GGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTT-LPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 DL IRV IAPG T L + + ++ + P RLG P + A+ + Sbjct: 175 FDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI-RRLGQPQDIANAALFLCS 233 Query: 243 --NPFLNGEVIRLDGA 256 +++G+++ + G Sbjct: 234 PAASWVSGQILTVSGG 249 >1DOH-A nrPDB Length = 283 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 68/272 (25%), Positives = 112/272 (41%), Gaps = 33/272 (12%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA----KKLGGNCIFAP 62 S++G VA++TG G+G A L +G ++ ++E E KK G + Sbjct: 26 SLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVK 85 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 ANV +++ A + FG++D+ + +G+ + T E+F RV +N Sbjct: 86 ANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSF------GHVKDVTPEEFDRVFTINT 139 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAF-EGQVGQAAYSASKGGIVGMTLP 181 G F V R + G +I S+ + A YS SKG I Sbjct: 140 RGQFFVAREAYKHLE--------IGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARC 191 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTL------------PDKVRNFLASQVPFPSRLGD 229 +A D+A I V +APG T + + ++V + A Q R+G Sbjct: 192 MAIDMADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGL 251 Query: 230 PAEYAHLVQMVIENP--FLNGEVIRLDGAIRM 259 P + A +V + N ++ G+VI +DG M Sbjct: 252 PIDIARVVCFLASNDGGWVTGKVIGIDGGACM 283 >1K2W-A nrPDB Length = 256 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 62/266 (23%), Positives = 106/266 (39%), Gaps = 23/266 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + G A+ITG A G+G + A+ V +GA + D+ A ++G +VT Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDVT 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + + + +++G ID+ VN A + + T E + R+ +N+ GT Sbjct: 62 DQASIDRCVAELLDRWGSIDILVNNAAL------FDLAPIVEITRESYDRLFAINVSGTL 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 +++ VA M GG+ G IIN AS A G+ Y A+K ++ +T +L Sbjct: 116 FMMQAVARAMIA-----GGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNL 170 Query: 187 APIGIRVVTIAPGLFATPLL----------TTLPDKVRNFLASQVPFPSRLGDPAEYAHL 236 GI V IAPG+ LP + R+G + + Sbjct: 171 IRHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGM 230 Query: 237 VQMVI--ENPFLNGEVIRLDGAIRMQ 260 + E ++ + +DG M Sbjct: 231 AIFLATPEADYIVAQTYNVDGGNWMS 256 >4HP8-A nrPDB Length = 247 Score = 203 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 106/255 (41%), Gaps = 20/255 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN-SEGETEAKKLGGNCIFAPANV 65 S++G A++TG +GLG + A L GA V E K GGN + Sbjct: 6 SLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDF 65 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + + T A D+ VN AGI + + D+ V++VNL Sbjct: 66 ADPLAAKDSFTDA-----GFDILVNNAGI------IRRADSVEFSELDWDEVMDVNLKAL 114 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F + A + G+ G ++N AS+ +F+G + +Y+A+K G+ G+T +A + Sbjct: 115 FFTTQAFAKELLAK-----GRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANE 169 Query: 186 LAPIGIRVVTIAPGLFATPLLTTL-PDKVRNFLASQVPFPSRLGDPAEYAHLVQMV--IE 242 A GI V IAPG T L D RN + R G + A + Sbjct: 170 WAAKGINVNAIAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAA 229 Query: 243 NPFLNGEVIRLDGAI 257 +++G ++ +DG Sbjct: 230 ADYVHGAILNVDGGW 244 >1HXH-A nrPDB Length = 253 Score = 203 bits (517), Expect = 6e-53, Method: Composition-based stats. Identities = 76/261 (29%), Positives = 119/261 (45%), Gaps = 21/261 (8%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++G VA++TGGASG+GL K L+G+GA D+ + G+ A +LG +F + Sbjct: 1 TNRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHD 60 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V+SE + + + + G ++V VN AGI + + LEDF R++ +N Sbjct: 61 VSSEADWTLVMAAVQRRLGTLNVLVNNAGILLP------GDMETGRLEDFSRLLKINTES 114 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 F + M + G IIN ASV+++ A YSASK + +T A Sbjct: 115 VFIGCQQGIAAMKET-------GGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAAL 167 Query: 185 DLAPIG--IRVVTIAPGLFATPLLTT-LPDKVRNFLASQVPFPSRLGD---PAEYAHLVQ 238 G IRV +I P TP++ LP V + P +R G P A LV Sbjct: 168 SCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVL 227 Query: 239 MVIEN--PFLNGEVIRLDGAI 257 + + ++G + D +I Sbjct: 228 FLASDESSVMSGSELHADNSI 248 >3V2H-A nrPDB Length = 281 Score = 202 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 74/274 (27%), Positives = 119/274 (43%), Gaps = 32/274 (11%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-----ETEAKKLGGNCIF 60 +S+ AVITG SG+GL+ A+ L GA VL + + A G + Sbjct: 21 QSMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLH 80 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 PA++T E+ + + ++FG D+ VN AG+ +K + +E + R+I V Sbjct: 81 HPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFV------EKIEDFPVEQWDRIIAV 134 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 NL +F+ IR M + G IIN AS ++AY A+K GI+G+T Sbjct: 135 NLSSSFHTIRGAIPPMKKK------GWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTK 188 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLT-TLPDKVR-----------NFLASQVPFPSRLG 228 +A ++A G+ V +I PG TPL+ +PD+ R + P Sbjct: 189 TVALEVAESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKK-FI 247 Query: 229 DPAEYAHLVQMVIENPF--LNGEVIRLDGAIRMQ 260 + A L + + + G + +DG Q Sbjct: 248 TVEQVASLALYLAGDDAAQITGTHVSMDGGWTAQ 281 >5YSS-A nrPDB Length = 256 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 115/267 (43%), Gaps = 25/267 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA-KKLGGNCIFAPANV 65 ++ G A++TG SG+GL A+ L GAT +L + + +A + G + A++ Sbjct: 2 NLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADL 61 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + E ++ + A+ +FG +D+ +N AGI H + ++ + +I +NL Sbjct: 62 SDEAQIADMMRYAESEFGGVDILINNAGIQ------HVSPIETFPVDKWNAIIAINLSSV 115 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 F+ RL M G IIN ASV ++AY A+K G+VG+T IA + Sbjct: 116 FHTTRLALPGMRARN------WGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALE 169 Query: 186 LAPIGIRVVTIAPGLFATPLLT----------TLPDKVRNFLASQVPFPSRLGDPAEYAH 235 A I + PG TPL+ P+ R+ L ++ P + + Sbjct: 170 TAQTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGN 229 Query: 236 LVQMVIENPF--LNGEVIRLDGAIRMQ 260 L + + + G +DG Q Sbjct: 230 LALFLCSDGAAQVRGVAWNMDGGWVAQ 256 >4DBZ-A nrPDB Length = 281 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 73/271 (26%), Positives = 117/271 (43%), Gaps = 27/271 (9%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCI 59 + + + VA++TG SG+GL A+RL +G + T E ++ G Sbjct: 19 SHMATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEAD 78 Query: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 +V S E++A + E++G +DV VN AG T E + V+ Sbjct: 79 GRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELAD------ELWLDVVE 132 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 NL G F V + V G E G I+N AS +G V A YSASK G+VG T Sbjct: 133 TNLTGVFRVTKQVLKAGGMLER----GTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFT 188 Query: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTL-----------PDKVRNFLASQVPFPSRLG 228 + +LA GI V + PG TP+ ++ ++ + + ++VP R Sbjct: 189 KALGLELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPI-GRYV 247 Query: 229 DPAEYAHLVQMVI--ENPFLNGEVIRLDGAI 257 P+E A +V +I + + + + G + Sbjct: 248 QPSEVAEMVAYLIGPGAAAVTAQALNVCGGL 278 >4E6P-A nrPDB Length = 259 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 62/268 (23%), Positives = 110/268 (41%), Gaps = 23/268 (8%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++ ++G A+ITG A G+G + A+ V +GAT + D+ A ++G + Sbjct: 3 MKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMD 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VT + + AA+ E G +D+ VN A + + T E ++++ +N+ G Sbjct: 63 VTRQDSIDAAIAATVEHAGGLDILVNNAAL------FDLAPIVEITRESYEKLFAINVAG 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T ++ A M G+ G IIN AS A G+ A Y A+K ++ +T Sbjct: 117 TLFTLQAAARQMIAQ-----GRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGL 171 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTL----------PDKVRNFLASQVPFPSRLGDPAEYA 234 DL I V IAPG+ + P + L + R+G + Sbjct: 172 DLIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLT 231 Query: 235 HLVQMVIE--NPFLNGEVIRLDGAIRMQ 260 + + + ++ + +DG M Sbjct: 232 GMAIFLASAESDYIVSQTYNVDGGNWMS 259 >3A28-C nrPDB Length = 258 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 72/266 (27%), Positives = 120/266 (45%), Gaps = 28/266 (10%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET-----EAKKLGGNCIFAPA 63 VA++TGGA G+G +++L G + D+P E + + +F Sbjct: 1 MSKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGL 60 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +VT + +A+ A EK G DV VN AGIA T ED +++ +VN+ Sbjct: 61 DVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLE------VTEEDLKQIYSVNVF 114 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 F I+ + + D+ G +G IIN AS+AA +G +AYS +K + G+T A Sbjct: 115 SVFFGIQAASR-----KFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAA 169 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV----------PFPSRLGDPAEY 233 ++LAP G V APG+ T + + ++ + R P + Sbjct: 170 QELAPKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDV 229 Query: 234 AHLVQMVIE--NPFLNGEVIRLDGAI 257 A LV + + ++ G+V+ +DG + Sbjct: 230 AGLVSFLASENSNYVTGQVMLVDGGM 255 >5EJ2-A nrPDB Length = 308 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 63/281 (22%), Positives = 116/281 (41%), Gaps = 41/281 (14%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDV---------------PNSEGETEA 51 V G VA I+G A G G S A RL +GA + +D+ +E Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 52 KKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL 111 K L + A +V + +++A+ E+ GR+D+ V AG+ + H+ ++ V Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNV--- 150 Query: 112 EDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS 171 +Q +I++NL G ++ ++ + GG+ G I+ T+SV + Y A+ Sbjct: 151 --WQDMIDINLTGVWHTVKAGVPHVL-----SGGRGGSIVLTSSVGGRKAYPNTGHYIAA 203 Query: 172 KGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTL--------------PDKVRNFL 217 K G++G+ A +L P IRV + P +T ++ PD Sbjct: 204 KHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPIS 263 Query: 218 ASQVPFPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGA 256 P D ++ ++ V + + ++ G + +D Sbjct: 264 QMMHTLPVPWVDASDISNAVLFLASDESRYVTGVSLPVDAG 304 >3U5T-A nrPDB Length = 267 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 80/254 (31%), Positives = 116/254 (45%), Gaps = 22/254 (8%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEA----KKLGGNCIFAPANVT 66 VA++TG + G+G + A RL G T V+ + E + GG + A A+V+ Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQADVS 87 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 V+ A+E FG +DV VN AGI F RVI VNL GTF Sbjct: 88 DPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAV------FDRVIAVNLKGTF 141 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 N +R A + G IIN ++ Y+A+K G+ MT ++++L Sbjct: 142 NTLREAAQRLR--------VGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKEL 193 Query: 187 APIGIRVVTIAPGLFATPL-LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--EN 243 I V +APG AT L L D+VR+ A P RLG P + A V + + Sbjct: 194 RGRDITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPLE-RLGTPQDIAGAVAFLAGPDG 252 Query: 244 PFLNGEVIRLDGAI 257 ++NG+V+R +G I Sbjct: 253 AWVNGQVLRANGGI 266 >2B4Q-A nrPDB Length = 276 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 116/259 (44%), Gaps = 14/259 (5%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG--GNCIFAPAN 64 S+ G +A++TGG+ G+G A+ L+ GA + A +L G+C PA+ Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 85 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 ++SE + E R+D+ VN AG + + + + +++V+ +N+ Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAAL------ESYPVSGWEKVMQLNVTS 139 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQA-AYSASKGGIVGMTLPIA 183 F+ I+ + ++ ++ + +IN SVA QA AY SK + ++ +A Sbjct: 140 VFSCIQQLLPLLRRSASAENP--ARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLA 197 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFP-SRLGDPAEYAHLVQMVI- 241 ++L I V IAPG F + + + + + A P R G P E A L + Sbjct: 198 KELVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAG 257 Query: 242 -ENPFLNGEVIRLDGAIRM 259 ++ G VI +DG + Sbjct: 258 TAGAYMTGNVIPIDGGFHL 276 >1X1T-A nrPDB Length = 260 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 71/270 (26%), Positives = 109/270 (40%), Gaps = 32/270 (11%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG-----ETEAKKLGGNCIFAP 62 +KG VAV+TG SG+GL A L QGA VL ++ A + G ++ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 A+++ + V+ + A + GRID+ VN AGI H + E + ++ +NL Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQ------HTALIEDFPTEKWDAILALNL 115 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 F+ M + G IIN AS ++AY A+K G+VG T Sbjct: 116 SAVFHGTAAALPHMKKQ------GFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVT 169 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLT----TLPDK--------VRNFLASQVPFPSRLGDP 230 A + A GI I PG TPL+ L +K R L+ + P P Sbjct: 170 ALETAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQ-FVTP 228 Query: 231 AEYAHLVQMVIENPF--LNGEVIRLDGAIR 258 + + + + G + +DG Sbjct: 229 EQLGGTAVFLASDAAAQITGTTVSVDGGWT 258 >3OIC-A nrPDB Length = 258 Score = 200 bits (508), Expect = 6e-52, Method: Composition-based stats. Identities = 54/259 (20%), Positives = 101/259 (38%), Gaps = 21/259 (8%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGNCIFAPAN 64 + A++TG + G+G + A RL G V+ + + E +KLG + AN Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V +++ E FGR+DV VN A V + + +N+N Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVL------RPVMELEETHWDWTMNINAKA 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + A +M +N G I++ +S+ + SK + +T +A Sbjct: 117 LLFCAQEAAKLMEKN------GGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAV 170 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLP--DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 +L+P I V ++ G T L P + + P R+ + + V+ ++ Sbjct: 171 ELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTP-AGRMVEIKDMVDTVEFLVS 229 Query: 243 N--PFLNGEVIRLDGAIRM 259 + + G+ I +DG + Sbjct: 230 SKADMIRGQTIIVDGGRSL 248 >2GDZ-A nrPDB Length = 267 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 66/261 (25%), Positives = 121/261 (46%), Gaps = 33/261 (12%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-----GGNCIFAP 62 V G VA++TG A G+G + A+ L+ +GA L+D G L +F Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V +++++ + FGR+D+ VN AG+ +++++ + +NL Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------------EKNWEKTLQINL 110 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP- 181 + + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 111 VSVISGTYLGLDYMSKQN---GGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSA 167 Query: 182 -IARDLAPIGIRVVTIAPGLFATPLLTTLPD--------KVRNFLASQVPFPSRLGDPAE 232 +A +L G+R+ I PG T +L ++ + ++ + + + + DP Sbjct: 168 ALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYG-ILDPPL 226 Query: 233 YAHLVQMVIENPFLNGEVIRL 253 A+ + +IE+ LNG ++++ Sbjct: 227 IANGLITLIEDDALNGAIMKI 247 >5B1Y-A nrPDB Length = 270 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 62/255 (24%), Positives = 111/255 (43%), Gaps = 24/255 (9%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGG-NCIFAPANVTS 67 A++TGG+ G+G +T R +G + V+ ++ EA++LG +V Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGD 85 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 V + E ++V VN AG+ + ++ +++ + VNL G + Sbjct: 86 PDSVTEMSSRVGELIPHLNVLVNAAGV------LQLGGIEETSISEWEETLRVNLTGVYL 139 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQV-GQAAYSASKGGIVGMTLPIARDL 186 V + + + I+N AS+A G V AYSASK G++G+T +A L Sbjct: 140 VTK------LLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQL 193 Query: 187 APIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYAHLVQMVIE-- 242 A GIRV +AP T + + D + R +AS P + P + A + + + Sbjct: 194 AGYGIRVNAVAPSFVETDMTRSFLDTPEKRERIASLHPL-KIILKPEDVAEAILFLADPR 252 Query: 243 -NPFLNGEVIRLDGA 256 + + G V+ ++ Sbjct: 253 RSRGITGHVLSINAG 267 >1P33-A nrPDB Length = 289 Score = 193 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 34/281 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLD-VPNSEGETEAKKLGGN----CIFAPANVT 66 VA++TG A LG S A+ L +G T L ++ T A L I A+++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 67 SEKE-----------------VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYH----EKK 105 + A + +GR DV VN A E Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 106 NQVHTLEDFQ----RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG 161 + V E + + N I + +I+ A + +Q G I+N + Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 162 QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV 221 +G Y+ +K + G+T A +LA + IRV ++PGL P +P V+ +V Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP--DDMPFSVQEDYRRKV 246 Query: 222 PFPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGAIRMQ 260 P R E + +V + ++ G I++DG + Sbjct: 247 PLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSLT 287 >2QHX-A nrPDB Length = 328 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 62/281 (22%), Positives = 105/281 (37%), Gaps = 34/281 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLD-VPNSEGETEAKKLGGN----CIFAPANVT 66 VA++TG A LG S A+ L +G L +E + L I A+++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 67 SEKE-----------------VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQ-- 107 + + +GR DV VN A ++ Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 108 --VHTLEDFQ----RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG 161 V E + + N I + +I+ A + G IIN + Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 162 QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV 221 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+V Sbjct: 228 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSKV 285 Query: 222 PFPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 P R AE + +V + + ++ G +++DG + Sbjct: 286 PLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 326 >2BFA-A nrPDB Length = 288 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 62/281 (22%), Positives = 105/281 (37%), Gaps = 34/281 (12%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLD-VPNSEGETEAKKLGGN----CIFAPANVT 66 VA++TG A LG S A+ L +G L +E + L I A+++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 67 SEKE-----------------VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQ-- 107 + + +GR DV VN A ++ Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 108 --VHTLEDFQ----RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG 161 V E + + N I + +I+ A + G IIN + Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 162 QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV 221 +G Y+ +KG + G+T A +LAP+ IRV + PGL + L+ +P V S+V Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL--SVLVDDMPPAVWEGHRSKV 245 Query: 222 PFPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 P R AE + +V + + ++ G +++DG + Sbjct: 246 PLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 286 >4FC7-A nrPDB Length = 277 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 115/258 (44%), Gaps = 22/258 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPA 63 ++ VA ITGG SG+G A+ + G V+ T A+KL G C+ Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 84 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + V AA+ A ++FGRID+ +NCA + F+ V++++ Sbjct: 85 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPA------GALSFNAFKTVMDIDTS 138 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 GTFNV R++ ++ GVI+N + GQ Q ++K + MT +A Sbjct: 139 GTFNVSRVLYEKFFRDH------GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 192 Query: 184 RDLAPIGIRVVTIAPGLFA-TPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 + P IRV ++APG + T L L P + + P RLG+ E AH V + Sbjct: 193 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSVLYL 251 Query: 241 IE--NPFLNGEVIRLDGA 256 ++ G V+ DG Sbjct: 252 ASPLASYVTGAVLVADGG 269 >4AVY-A nrPDB Length = 242 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 70/253 (27%), Positives = 107/253 (42%), Gaps = 27/253 (10%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 G ++TGG+SG+G + A + GA V L + ++T Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRH---PRIRREELDITDS 66 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 + +Q R+DV VN AGI+ + + + L F+RV+ +NL Sbjct: 67 QRLQRLFEA----LPRLDVLVNNAGIS--------RDREEYDLATFERVLRLNLSAAMLA 114 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 +L ++ Q + G I+N AS+ + G + AYSASKG IV +T +A + A Sbjct: 115 SQLARPLLAQ-------RGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAA 167 Query: 189 IGIRVVTIAPGLFATPLLTTLPDKVRN--FLASQVPFPSRLGDPAEYAHLVQMVI--ENP 244 IRV IAPG TPL L V + + P R G+ E A + Sbjct: 168 ERIRVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLA-RWGEAPEVASAAAFLCGPGAS 226 Query: 245 FLNGEVIRLDGAI 257 F+ G V+ +DG Sbjct: 227 FVTGAVLAVDGGY 239 >3ZV3-A nrPDB Length = 281 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 65/265 (24%), Positives = 106/265 (40%), Gaps = 21/265 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G VA+ITGGASGLG + R V +GA +LD GGN + +V S Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVRS 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 ++ + A FG+ID + AGI + F + +VN+ G + Sbjct: 63 LQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKID-AAFDDIFHVNVKGYIH 121 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 ++ + RG ++ T S A F G Y+A+K +VG+ +A +LA Sbjct: 122 AVKACLPALV-------SSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELA 174 Query: 188 PIGIRVVTIAPGLFATPL---------LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 P +RV +APG T L ++ + V R+ EY Sbjct: 175 PH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYV 233 Query: 239 MVI---ENPFLNGEVIRLDGAIRMQ 260 ++ G ++ DG + ++ Sbjct: 234 FFATRGDSLPATGALLNYDGGMGVR 258 >5JS6-A nrPDB Length = 274 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 110/242 (45%), Gaps = 23/242 (9%) Query: 27 AKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRID 86 + V GA V+ D S G ++L G +F +VT E +V+ ++ +FGR+D Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPG-AVFILCDVTQEDDVKTLVSETIRRFGRLD 86 Query: 87 VAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQ 146 VN AG + + + + + F++++ +NL+GT+ + +L + +++ Sbjct: 87 CVVNNAGHHPPPQ-----RPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ------ 135 Query: 147 RGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLL 206 G +IN +S+ GQ Y A+KG + MT +A D +P G+RV I+PG TPL Sbjct: 136 -GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLW 194 Query: 207 TTLP-------DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE-NPFLNGEVIRLDGAIR 258 L +R + +Q R+G PAE + F G + + G Sbjct: 195 EELAALMPDPRATIREGMLAQ--PLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAE 252 Query: 259 MQ 260 + Sbjct: 253 LG 254 >1O5I-A nrPDB Length = 249 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 50/256 (19%), Positives = 96/256 (37%), Gaps = 28/256 (10%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 + ++ + G+G + A L +GA + + + ++ + Sbjct: 18 RDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKR------SGHRYVVCDLRKD 71 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 L L EK +D+ V AG A T EDF+ I+ + + Sbjct: 72 ------LDLLFEKVKEVDILVLNAGGPKA------GFFDELTNEDFKEAIDSLFLNMIKI 119 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP 188 +R M + G I+ S + ++++ + G ++ ++AP Sbjct: 120 VRNYLPAMKEK------GWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAP 173 Query: 189 IGIRVVTIAPGLFATPLLTT-LPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPF 245 GI V +APG T + L ++ + + SQ+P R+ P E A +V + + Sbjct: 174 YGITVNCVAPGWTETERVKELLSEEKKKQVESQIPM-RRMAKPEEIASVVAFLCSEKASY 232 Query: 246 LNGEVIRLDGAIRMQP 261 L G+ I +DG + P Sbjct: 233 LTGQTIVVDGGLSKFP 248 >3UF0-A nrPDB Length = 273 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 108/257 (42%), Gaps = 20/257 (7%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN--SEGETEAKKLGGNCIFAPAN 64 S+ G AV+TG SG+G + A GA + + E E GG+ A+ Sbjct: 28 SLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVAD 87 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 + + R+DV VN AGI + +L ++ V+ VNL Sbjct: 88 LADLEGAANVAEELAATR-RVDVLVNNAGI------IARAPAEEVSLGRWREVLTVNLDA 140 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + + R M + G I+ AS+ +F+G AAY+ASK +VG+T +A Sbjct: 141 AWVLSRSFGTAMLAH------GSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALAS 194 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 + A G+ V +APG T L D+ + +++P R P + + Sbjct: 195 EWAGRGVGVNALAPGYVVTANTAALRADDERAAEITARIP-AGRWATPEDMVGPAVFLAS 253 Query: 243 N--PFLNGEVIRLDGAI 257 + +++G+V+ +DG Sbjct: 254 DAASYVHGQVLAVDGGW 270 >3GDF-A nrPDB Length = 267 Score = 187 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 58/265 (21%), Positives = 101/265 (38%), Gaps = 25/265 (9%) Query: 7 SVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNSEGETE-----AKKLGGNCI 59 S+KG V V+TG + G+G+ A+ GA + ++G E K G Sbjct: 17 SLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAK 76 Query: 60 FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 V S + + + FG+ID + AG ++E + V+ Sbjct: 77 AYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILD------GSVEAWNHVVQ 130 Query: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQV--GQAAYSASKGGIVG 177 V+L GTF+ + V + G ++ TAS++ Q +Y+ +K G + Sbjct: 131 VDLNGTFHCAKAVGHHFKER------GTGSLVITASMSGHIANFPQEQTSYNVAKAGCIH 184 Query: 178 MTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLV 237 M +A + RV +I+PG T L +P + + S +P R G E Sbjct: 185 MARSLANEWRDFA-RVNSISPGYIDTGLSDFVPKETQQLWHSMIPM-GRDGLAKELKGAY 242 Query: 238 QMVIENP--FLNGEVIRLDGAIRMQ 260 + + G + +DG + Sbjct: 243 VYFASDASTYTTGADLLIDGGYTTR 267 >3D3W-A nrPDB Length = 244 Score = 187 bits (474), Expect = 5e-48, Method: Composition-based stats. Identities = 49/254 (19%), Positives = 99/254 (38%), Gaps = 21/254 (8%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G ++TG G+G T + L GA V + ++ ++ ++ G ++ Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG-IEPVCVDLGD 63 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + + AL G +D+ VN A +A+ T E F R VNL Sbjct: 64 WEATERALGSV----GPVDLLVNNAAVALLQPFLE------VTKEAFDRSFEVNLRAVIQ 113 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 V ++VA + G G I+N +S + + Y ++KG + +T +A +L Sbjct: 114 VSQIVARGLIAR-----GVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELG 168 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNF--LASQVPFPSRLGDPAEYAHLVQMVIEN-- 243 P IRV + P + T + + +++P + + + + ++ + Sbjct: 169 PHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPL-GKFAEVEHVVNAILFLLSDRS 227 Query: 244 PFLNGEVIRLDGAI 257 G + ++G Sbjct: 228 GMTTGSTLPVEGGF 241 >4TRR-A nrPDB Length = 269 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 62/272 (22%), Positives = 117/272 (43%), Gaps = 27/272 (9%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFA 61 + ++ G AV+TG ASG+G A L GA + D+ E K GG I Sbjct: 9 MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGV 68 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 +VT+E+ V + E FG +D+ V+ AGI + + ++ D++++ ++ Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNP------IENYSFADWKKMQAIH 122 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + G F + M +++ + GV+I SV + E ++AY +K G++G+ Sbjct: 123 VDGAFLTTKAALKHMYKDD-----RGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARV 177 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLT-TLPDKVRNFLASQVPFPSR----------LGDP 230 +A++ A +R + PG TPL+ +P++ + S+ + Sbjct: 178 LAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTV 237 Query: 231 AEYAHLVQMVIE--NPFLNGEVIRLDGAIRMQ 260 + A V + + L G+ + MQ Sbjct: 238 QDVAQTVLFLSAFPSAALTGQSFIVSHGWFMQ 269 >3UN1-A nrPDB Length = 260 Score = 185 bits (470), Expect = 1e-47, Method: Composition-based stats. Identities = 61/253 (24%), Positives = 107/253 (42%), Gaps = 20/253 (7%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 ++ + V VITG + G+G + + V + Sbjct: 22 SMMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRS------IKPSADPDIHTVAG 75 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +++ + + E+FGRID VN AG+ +A K T ED+ + VN+ Sbjct: 76 DISKPETADRIVREGIERFGRIDSLVNNAGVFLA------KPFVEMTQEDYDHNLGVNVA 129 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G F++ + A M + QG V I T+ V + A S +KGG+ +T +A Sbjct: 130 GFFHITQRAAAEMLK----QGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLA 185 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN 243 + + G+RV ++PG+ TP+ P + + LA P R+G+ + V + Sbjct: 186 MEFSRSGVRVNAVSPGVIKTPMH---PAETHSTLAGLHPV-GRMGEIRDVVDAVLYLEHA 241 Query: 244 PFLNGEVIRLDGA 256 F+ GE++ +DG Sbjct: 242 GFITGEILHVDGG 254 >4CR6-A nrPDB Length = 271 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 69/255 (27%), Positives = 111/255 (43%), Gaps = 10/255 (3%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + G A++TG A G+G +T + + +GA+ V +D+ T ++ G I ++ Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG--AIPIACDLA 69 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + AA+ A + G +D+ V + + + + D+ R ++VN+ GTF Sbjct: 70 DRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDA-----DWDRYVDVNMTGTF 124 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R A M + G+ II SV +F + AAY A+KGG+ +T +A DL Sbjct: 125 LTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDL 184 Query: 187 APIGIRVVTIAPGLFA-TPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN-- 243 A GI V IAPG T T + R G P E A + E+ Sbjct: 185 ARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAEDGS 244 Query: 244 PFLNGEVIRLDGAIR 258 F+ G I +DG + Sbjct: 245 SFITGSTITIDGGLS 259 >2AG5-A nrPDB Length = 246 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 62/265 (23%), Positives = 108/265 (40%), Gaps = 28/265 (10%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 + + G V ++T A G+G + A +GA + D+ S+ + K G + Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVL--D 58 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VT +K++ + R+DV N AG H +D+ +N+N+ Sbjct: 59 VTKKKQIDQFANEVE----RLDVLFNVAGFV------HHGTVLDCEEKDWDFSMNLNVRS 108 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSASKGGIVGMTLPIA 183 + +I+ M + G IIN +SVA+ +G V + YS +K ++G+T +A Sbjct: 109 MYLMIKAFLPKMLAQ------KSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA 162 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTT------LPDKVRNFLASQVPFPSRLGDPAEYAHLV 237 D GIR + PG TP L P++ RN + R E A L Sbjct: 163 ADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQ-KTGRFATAEEIAMLC 221 Query: 238 QMVIEN--PFLNGEVIRLDGAIRMQ 260 + + ++ G + +DG + Sbjct: 222 VYLASDESAYVTGNPVIIDGGWSLG 246 >1H5Q-A nrPDB Length = 265 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 64/263 (24%), Positives = 112/263 (42%), Gaps = 25/263 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLGGNCIFAP 62 S ++TGG G+GL+ + + GA ++ ++ E K+ G Sbjct: 11 SFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQ 70 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V++ V + G I + AG++V K T EDF V +VN+ Sbjct: 71 CDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVV------KPATELTHEDFAFVYDVNV 124 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAA-------FEGQVGQAAYSASKGGI 175 G FN R VA + Q + Q+G I+ T+S+++ G + Q Y++SK Sbjct: 125 FGVFNTCRAVAKLWLQKQ-----QKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAAC 179 Query: 176 VGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAH 235 + +A + A GIRV ++PG T + K+R+ AS +P +R P E Sbjct: 180 SNLVKGLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPL-NRFAQPEEMTG 238 Query: 236 LVQMVIEN--PFLNGEVIRLDGA 256 +++ + ++ G +DG Sbjct: 239 QAILLLSDHATYMTGGEYFIDGG 261 >1CYD-A nrPDB Length = 244 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 61/255 (23%), Positives = 106/255 (41%), Gaps = 21/255 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 + GL A++TG G+G T K L GA V + NS+ + AK+ G ++ Sbjct: 4 NFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG-IEPVCVDLG 62 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + AL G +D+ VN A + + + T E F R +VNL F Sbjct: 63 DWDATEKALGGI----GPVDLLVNNAALVI------MQPFLEVTKEAFDRSFSVNLRSVF 112 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 V ++VA M G G I+N +S+ A YS++KG + +T +A +L Sbjct: 113 QVSQMVARDMINR-----GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMEL 167 Query: 187 APIGIRVVTIAPGLFATPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN- 243 P IRV ++ P + T + + + L + P + + + + + ++ + Sbjct: 168 GPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPL-RKFAEVEDVVNSILFLLSDR 226 Query: 244 -PFLNGEVIRLDGAI 257 +G I +D Sbjct: 227 SASTSGGGILVDAGY 241 >2BGM-A nrPDB Length = 278 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 19/241 (7%) Query: 27 AKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI--FAPANVTSEKEVQAALTLAKEKFGR 84 AK V GA V+ D+ + G+ +G + F +VT +++V+ + K G+ Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 85 IDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQG 144 +D+ G+ EDF+RV+++N+ G F V + A VM Sbjct: 93 LDIMFGNVGVLSTTPY----SILEAGNEDFKRVMDINVYGAFLVAKHAARVMI------P 142 Query: 145 GQRGVIINTASVAAFEGQVGQAA-YSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFAT 203 ++G I+ TAS+++F G + Y+A+K ++G+T + +L GIRV ++P + A+ Sbjct: 143 AKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVAS 202 Query: 204 PLLTTL----PDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPFLNGEVIRLDGAI 257 PLLT + +V L + A V + E+ +++G + +DG Sbjct: 203 PLLTDVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGY 262 Query: 258 R 258 Sbjct: 263 T 263 >1BDB-A nrPDB Length = 277 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 62/265 (23%), Positives = 104/265 (39%), Gaps = 21/265 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 +KG +ITGGASGLG + R V +GA +LD G N + +V S Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRS 62 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 ++ + A + +FG+ID + AGI + + F V ++N+ G + Sbjct: 63 LEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLD-AAFDEVFHINVKGYIH 121 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 ++ + RG +I T S A F G Y+A+K IVG+ +A +LA Sbjct: 122 AVKACLPALV-------ASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELA 174 Query: 188 PIGIRVVTIAPGLFATPL---------LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 P +RV + G + L + + V R+ + EY Sbjct: 175 PY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYV 233 Query: 239 MVI---ENPFLNGEVIRLDGAIRMQ 260 + G ++ DG + ++ Sbjct: 234 FFATRGDAAPATGALLNYDGGLGVR 258 >5IZ4-A nrPDB Length = 271 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 78/261 (29%), Positives = 123/261 (47%), Gaps = 19/261 (7%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSE------GETEAKKLGGNCIFAPANV 65 V VITG ASG+G +TA R G + + + +S E + G + A+V Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + + + A+ + ++ RID +NCAG I H +Q+ E F+RV VNLIG Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIP--HNAFDQIDDFE-FERVYRVNLIGL 132 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + + R ++ E + ++N +S+A G AY+ASKG + +TL +AR+ Sbjct: 133 YQMTRAAVPLL--RESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARN 190 Query: 186 LAPIGIRVVTIAPGLFATPLL-----TTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 LAP IRV +APG+ LL D V + + P R+ PAE A L + Sbjct: 191 LAPH-IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPL-KRVSRPAEIAELAWFL 248 Query: 241 -IENPFLNGEVIRLDGAIRMQ 260 P + G+VI + + + Sbjct: 249 TAHAPAITGQVIAAENGLLLG 269 >4RGB-A nrPDB Length = 294 Score = 180 bits (457), Expect = 5e-46, Method: Composition-based stats. Identities = 70/287 (24%), Positives = 120/287 (41%), Gaps = 42/287 (14%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPN---------------SEGE 48 + S+ G V ITG A G G S A QGA V +D+ E Sbjct: 19 GMGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETA 78 Query: 49 TEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQV 108 +K G +F A+V + +Q E+FG ID + AG+ + + Sbjct: 79 RLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDAS--- 135 Query: 109 HTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFE----GQVG 164 E + +++ LIG +N ++ M + GQ G +I T+S+ A G+ G Sbjct: 136 ---EALRLGLDIMLIGVWNTFQVAIPHMKER-----GQGGNLIATSSMIALLDLTDGRGG 187 Query: 165 QAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVR---------N 215 AY SK I G+ A LA IRV +AP +TP++T P + N Sbjct: 188 TDAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVN 247 Query: 216 FLASQVPFPSRLGDPAEYAHLVQMVIENP--FLNGEVIRLDGAIRMQ 260 +++ +P + +P + ++ + +I + G V+++D + ++ Sbjct: 248 AMSTALPDFP-MIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVK 293 >4DA9-A nrPDB Length = 280 Score = 180 bits (457), Expect = 5e-46, Method: Composition-based stats. Identities = 71/255 (27%), Positives = 111/255 (43%), Gaps = 13/255 (5%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAPANVTS 67 VA++TGG G+GL A+ L G + + ++EG E LG IF A++ Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 QA + +FGRID VN AGIA + E+F ++ VNL GT Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIA----SIVRDDFLDLKPENFDTIVGVNLRGTVF 146 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 + V M ++ IIN SV+A + Y SK G+ + +A LA Sbjct: 147 FTQAVLKAMLASDARASR---SIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLA 203 Query: 188 PIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVI--ENPF 245 GI V + PG+ + + + K + S + R G+P + ++V + + F Sbjct: 204 ETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLVPMRRWGEPEDIGNIVAGLAGGQFGF 263 Query: 246 LNGEVIRLDGAIRMQ 260 G VI+ DG + + Sbjct: 264 ATGSVIQADGGLSIG 278 >5JY1-A nrPDB Length = 274 Score = 179 bits (455), Expect = 9e-46, Method: Composition-based stats. Identities = 64/260 (24%), Positives = 114/260 (43%), Gaps = 20/260 (7%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG---ETEAKKLGGNCIFAPAN 64 ++ VA++TG G+G A+ +GA ++ ++ S G E E +++GG +F + Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 VTS+ ++AA+ A E+FG +D+ VN A + EK +++ ++ + +L Sbjct: 72 VTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEML-----EQTLTTSLWA 126 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 T+ +R M + + G I+N S+ G Y+ +K GIVG+T A Sbjct: 127 TWWAMRAAFVPMRER------RWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAAS 180 Query: 185 DLAPIGIRVVTIAPGLFATPLLT--TLPDKVRNFLASQVPFPSRLGDPA-EYAHLVQMVI 241 + I V IAP + A+ P R GDP + Sbjct: 181 EWGRFNITVNAIAPTAMGATFFELAAKNPEFAERSAAARPL-GRSGDPEQDIGPAAVFFA 239 Query: 242 E--NPFLNGEVIRLDGAIRM 259 + F+ GE + +DG + + Sbjct: 240 SEMSRFVTGETLHVDGGLHL 259 >5O3Z-A nrPDB Length = 263 Score = 176 bits (448), Expect = 5e-45, Method: Composition-based stats. Identities = 72/268 (26%), Positives = 110/268 (41%), Gaps = 31/268 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-----GGNCIFAPANVT 66 VAV+ GG LG + L G + D+ S A + G + T Sbjct: 8 VAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDAT 67 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E V+A E FGR D+ V AG+A A L DF + VNL+G F Sbjct: 68 DEASVEALARAVDETFGRADLLVYSAGVAKAAPITQ------FRLTDFDLSLQVNLVGYF 121 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 R + +M ++ G +G II S + G + YSA+K G VG+T +A DL Sbjct: 122 LCSREFSKLMIRD-----GIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDL 176 Query: 187 APIGIRVVTIAPG-LFATPLLTTL-----------PDKVRNFLASQVPFPSRLGDPAEYA 234 A GI V ++ G L +P+ +L P++V + +VP R D + Sbjct: 177 AEYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPL-KRGCDYQDVL 235 Query: 235 HLVQMVIENP--FLNGEVIRLDGAIRMQ 260 +++ + + G+ I + G M Sbjct: 236 NVLLFYASDKAAYCTGQSINVTGGQVMF 263 >3V8B-A nrPDB Length = 283 Score = 176 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 68/265 (25%), Positives = 110/265 (41%), Gaps = 30/265 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKK---LGGNCIFAPANVTSE 68 VA+ITG SG+G +TA L G T L +E E A + GG I A+V+ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 +++ A+ KFG +D+ V AGI + K ++ I VNL GTF Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPF-----EWDETIAVNLRGTFLT 144 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG--QVGQAAYSASKGGIVGMTLPIARDL 186 + L + Q G I+ +S+ G AY+A+K V + +A +L Sbjct: 145 LHLTVPYLKQR------GGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALEL 198 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFP----------SRLGDPAEYAHL 236 IRV + PG T + K+R+ + +P + G + A L Sbjct: 199 GKHHIRVNAVCPGAIETNISDNT--KLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAEL 256 Query: 237 VQMVIE--NPFLNGEVIRLDGAIRM 259 ++ ++ + G + +DG + Sbjct: 257 IRFLVSERARHVTGSPVWIDGGQGL 281 >2FWM-X nrPDB Length = 250 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 59/269 (21%), Positives = 103/269 (38%), Gaps = 32/269 (11%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 G +TG G+G +TA V GA D + T+ + + Sbjct: 1 GHMDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----QAFTQEQYPFATEV---M 53 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V +V + R+D VN AGI + ED+Q+ VN+ Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALVNAAGI------LRMGATDQLSKEDWQQTFAVNVG 107 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 G FN+ + + + G I+ AS AA ++G +AY ASK + + L + Sbjct: 108 GAFNLFQQTMNQFRRQ------RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVG 161 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLP-----DKVR-----NFLASQVPFPSRLGDPAEY 233 +LA G+R ++PG T + TL ++ R +P ++ P E Sbjct: 162 LELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEI 220 Query: 234 AHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 A+ + + + + + I +DG + Sbjct: 221 ANTILFLASDLASHITLQDIVVDGGSTLG 249 >3PXX-A nrPDB Length = 287 Score = 170 bits (432), Expect = 4e-43, Method: Composition-based stats. Identities = 64/301 (21%), Positives = 104/301 (34%), Gaps = 58/301 (19%) Query: 2 AAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLD---------------VPNSE 46 ++ V+ V ++TGGA G G S A +L +GA +L D E Sbjct: 2 PGSMGRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEE 61 Query: 47 GETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKN 106 E +K G A +V V L A +FG++DV V AGI Sbjct: 62 AGLEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHL----- 116 Query: 107 QVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFE------ 160 ++ F +V+ +G N + + II T SVA Sbjct: 117 ---PVQAFADAFDVDFVGVINTVHAALPYLT--------SGASIITTGSVAGLIAAAQPP 165 Query: 161 -----GQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLP----- 210 G A YS +K + TL +A LAP IR I P T +L + P Sbjct: 166 GAGGPQGPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQF 225 Query: 211 ---------DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRM 259 + P+ + ++ ++ V + + ++ G ++D + Sbjct: 226 RPDLEAPSRADALLAFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 Query: 260 Q 260 + Sbjct: 286 K 286 >3OML-A nrPDB Length = 613 Score = 170 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 61/248 (24%), Positives = 99/248 (39%), Gaps = 38/248 (15%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLD------------VPNSEGETEAKKLGG 56 G VAV+TG +GLG A +GA V+ D E +K GG Sbjct: 18 DGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGG 77 Query: 57 NCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 + A+ S + + A + FGR+D+ VN AGI ++ + +D+ Sbjct: 78 EAV---ADYNSVIDGAKVIETAIKAFGRVDILVNNAGI------LRDRSLVKTSEQDWNL 128 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 V +V+L G+F + M + G II T+S + G GQ Y+A+K G++ Sbjct: 129 VNDVHLKGSFKCTQAAFPYMKKQN------YGRIIMTSSNSGIYGNFGQVNYTAAKMGLI 182 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHL 236 G+ +A + A + I P + LPD + N L ++ A + Sbjct: 183 GLANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKL-----------IAPV 231 Query: 237 VQMVIENP 244 V + Sbjct: 232 VAYLCHES 239 >4EGF-A nrPDB Length = 266 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 72/266 (27%), Positives = 105/266 (39%), Gaps = 20/266 (7%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----NC 58 A V + G A+ITG G+G A+ GA VL SE + + LG + Sbjct: 13 AGVLRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDV 72 Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 ++ A E FG +DV VN AGI+ H + + F I Sbjct: 73 HTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGIS------HPQPVVDTDPQLFDATI 126 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 VNL + V M G+ G II AS AA AY SK G+V Sbjct: 127 AVNLRAPALLASAVGKAMVA-----AGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMA 181 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTL--PDKVRNFLASQVPFPSRLGDPAEYAHL 236 T +AR+L P GIR ++ P + T + + + + +++P R P E + Sbjct: 182 TKVLARELGPHGIRANSVCPTVVLTEMGQRVWGDEAKSAPMIARIPL-GRFAVPHEVSDA 240 Query: 237 VQMVIEN--PFLNGEVIRLDGAIRMQ 260 V + + +NG I +DG M Sbjct: 241 VVWLASDAASMINGVDIPVDGGYTMG 266 >4GKB-A nrPDB Length = 258 Score = 166 bits (421), Expect = 7e-42, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE--TEAKKLGGNCIFAPAN 64 +++ V ++TGGASG+G + + RL + A V+ +G + + P Sbjct: 4 NLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVE 63 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 + + + + A+ FGR+D VN AG+ I + V +LE NLI Sbjct: 64 LQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLER-------NLIH 116 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 + + + RG I+N +S A GQ + Y ASKG + +T A Sbjct: 117 YYAMAHYCVPHLKAT-------RGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAV 169 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTL------PDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 L G+RV + P TPL P+ +A++VP R P E A Sbjct: 170 ALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAV 229 Query: 239 MVIE--NPFLNGEVIRLDGAIR 258 ++ GE + +DG Sbjct: 230 FLLSPRASHTTGEWLFVDGGYT 251 >2NWQ-A nrPDB Length = 272 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 56/241 (23%), Positives = 92/241 (38%), Gaps = 21/241 (8%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA--N 64 S ITG SG G + A+R G + VL + A +L P + Sbjct: 18 SHMSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLD 77 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 V + AA+ E+F + +N AG+A+ Q L+D+ +++ N+ G Sbjct: 78 VRDRAAMSAAVDNLPEEFATLRGLINNAGLALGT-----DPAQSCDLDDWDTMVDTNIKG 132 Query: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 RL+ + + G I+N SVA G Y +K + +L + Sbjct: 133 LLYSTRLLLPRLIAH-----GAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRC 187 Query: 185 DLAPIGIRVVTIAPGLFATP--LLTTLPDKVR--NFLASQVPFPSRLGDPAEYAHLVQMV 240 DL G+RV + PGL + L+ D+ R A P P + A + + Sbjct: 188 DLQGTGVRVTNLEPGLCESEFSLVRFGGDQARYDKTYAGAHPI-----QPEDIAETIFWI 242 Query: 241 I 241 + Sbjct: 243 M 243 >3RKU-A nrPDB Length = 287 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 55/251 (21%), Positives = 94/251 (37%), Gaps = 28/251 (11%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRL--VGQGATAVLLDVPNSEGETEAKK------LG 55 A + +ITG ++G+G +TA G ++L E E KK Sbjct: 27 AAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPN 86 Query: 56 GNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ 115 A ++T ++++ + ++F ID+ VN AG A+ + ED Q Sbjct: 87 AKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGS-----DRVGQIATEDIQ 141 Query: 116 RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 V + N+ N+ + V + G I+N S+A + + Y ASK + Sbjct: 142 DVFDTNVTALINITQAVLPIFQAKN------SGDIVNLGSIAGRDAYPTGSIYCASKFAV 195 Query: 176 VGMTLPIARDLAPIGIRVVTIAPGLFATPL----LTTLPDKVRNFLASQVPFPSRLGDPA 231 T + ++L IRV+ IAPGL T ++ +N P Sbjct: 196 GAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLM-----AD 250 Query: 232 EYAHLVQMVIE 242 + A L+ Sbjct: 251 DVADLIVYATS 261 >5ILO-A nrPDB Length = 271 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 64/213 (30%), Positives = 101/213 (47%), Gaps = 23/213 (10%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGA-TAVLLDVPNSEGE---TEAKKLGGNCIFAP 62 S +G AV+TGGA G+GL +K+L+ GA ++D+ ++ E A + + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V ++K V+A + FG ID+ VN AGI +D QR + VNL Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFND--------------KDVQRTLLVNL 117 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 G N MG+ D GG+ G+++N +SV + Y A+K GI+ T + Sbjct: 118 GGIINSTLSALPYMGK---DNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCL 174 Query: 183 ARD--LAPIGIRVVTIAPGLFATPLLTTLPDKV 213 A + GI+ VT+ PG T + T +K+ Sbjct: 175 ANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKI 207 >3U4C-A nrPDB Length = 281 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 54/266 (20%), Positives = 94/266 (35%), Gaps = 35/266 (13%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS-----EGETEAKKLGGNCIFAPANV 65 A + G + G+G + A +L Q + V+ + + AK + I ++ Sbjct: 24 RTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDM 83 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + + + + GR+DV +N I +ED + Sbjct: 84 SDQHTRAGIFQKIESQCGRLDVLINN------IPGGAPDTFDNCNIEDMTATFTQKTVAY 137 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS--KGGIVGMTLPIA 183 + I+ + +M QNE G IIN V + G ++ S ++ + I+ Sbjct: 138 IDAIKRASSLMKQNE------FGRIINI--VGNLWKEPGANMFTNSMMNAALINASKNIS 189 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPD-----------KVRNFLASQVPFPSRLGDPAE 232 LAP I V + PG AT + K +AS +P R+G E Sbjct: 190 IQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPM-KRVGSAEE 248 Query: 233 YAHLVQMVIE--NPFLNGEVIRLDGA 256 A L + ++ G+ I DG Sbjct: 249 TAALAAFLASEEASYITGQQISADGG 274 >4DRY-A nrPDB Length = 281 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 61/251 (24%), Positives = 96/251 (38%), Gaps = 25/251 (9%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN--- 57 MA S +G +A++TGG +G+G A+ L +G + V+ + A ++GG Sbjct: 24 MAQGKGSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGN 83 Query: 58 -CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 +V +V A + +F R+D+ VN AG V E T E + Sbjct: 84 IVRAVVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEV-----TFEQWNG 138 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 ++ NL G F + +M P + G IIN S++A + A Y+A+K I Sbjct: 139 IVAANLTGAFLCTQHAFRMMKAQTP----RGGRIINNGSISAQTPRPNSAPYTATKHAIT 194 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRN-----FLASQVPFPSRLGDPA 231 G+T A D I I G AT + + V +P Sbjct: 195 GLTKSTALDGRMHDIACGQIDIGNAATDMTARMSTGVLQANGEVAAEPTIPI-------E 247 Query: 232 EYAHLVQMVIE 242 A V + Sbjct: 248 HIAEAVVYMAS 258 >4HBG-A nrPDB Length = 286 Score = 139 bits (350), Expect = 1e-33, Method: Composition-based stats. Identities = 59/284 (20%), Positives = 103/284 (36%), Gaps = 70/284 (24%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG--------------- 56 VA++TG G+G + ++L +G + ++L E A G Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 57 ------------------------------NCIFAPANVTSEKEVQAALTLAKEKFGRID 86 + +F P N S E + + + Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYV----------N 115 Query: 87 VAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNE---PDQ 143 + +NCAG+ E + T Q ++NVN + + + M +++ P+ Sbjct: 116 LLINCAGLT------QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 Query: 144 GGQRGV--IINTASV--AAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPG 199 GQ I+N +S+ + G + YSASK + T +A ++ P IR TI+PG Sbjct: 170 SGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 Query: 200 LFA-TPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 L T ++ LP + + L + PAE A V + Sbjct: 230 LVKGTDMIQNLPVEAKEMLERTIGASG-TSAPAEIAEEVWSLYS 272 >1W73-A nrPDB Length = 302 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 55/260 (21%), Positives = 100/260 (38%), Gaps = 21/260 (8%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVP----NSEGETEAKKLGGNCIFA 61 S +G VA ITGG +GLG L GA V+ + E + + G Sbjct: 22 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAI 81 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 +V VQ ++ + G ++ +N A T N ++ + ++ Sbjct: 82 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNA------WKTITDIV 135 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 L GT V + + + + + ++ ++ A G +++K G+ M+ Sbjct: 136 LNGTAFVTLEIGKQLIKAQ-----KGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKS 190 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPD---KVRNFLASQVPFPSRLGDPAEYAHLVQ 238 +A + G+R I PG T + D + ++P RLG E A+L Sbjct: 191 LAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIP-CGRLGTVEELANLAA 249 Query: 239 MVIEN--PFLNGEVIRLDGA 256 + + ++NG VI+ DG Sbjct: 250 FLCSDYASWINGAVIKFDGG 269 >2P91-A nrPDB Length = 285 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 44/259 (16%), Positives = 96/259 (37%), Gaps = 16/259 (6%) Query: 8 VKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPN--SEGETEAKKLGGNCIFAPA 63 ++G A+ITG A + AK +GA + E K G+ + Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKC 78 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V+ +++++ +E +G +D+ V IA A K + + E F+ +++++ Sbjct: 79 DVSLDEDIKNLKKFLEENWGSLDIIV--HSIAYAPKEEFKGGVIDTSREGFKIAMDISVY 136 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + R + +M G+ G I+ + A + +K + +A Sbjct: 137 SLIALTRELLPLME-------GRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLA 189 Query: 184 RDLAPIGIRVVTIAPGLFAT-PLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 D+A G R+ I+ G T + + ++V + + + Sbjct: 190 YDIAKHGHRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCS 249 Query: 243 N--PFLNGEVIRLDGAIRM 259 + + GEV+ +D + Sbjct: 250 DWARAITGEVVHVDNGYHI 268 >1A27-A nrPDB Length = 289 Score = 135 bits (341), Expect = 2e-32, Method: Composition-based stats. Identities = 61/252 (24%), Positives = 98/252 (38%), Gaps = 39/252 (15%) Query: 12 VAVITGGASGLGLSTAKRLVGQGA-----TAVLLDVPNSEGETEAKKL----GGNCIFAP 62 V +ITG +SG+GL A RL + A L D+ EA + G+ Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V K V AA E GR+DV V AG+ + ++ V + V++VN+ Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 115 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +GT +++ M + G ++ T SV G Y ASK + G+ + Sbjct: 116 VGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 169 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTL---PDKVRN-------------FLASQVPFPSR 226 A L P G+ + I G T + + P++V + S+ F Sbjct: 170 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREA 229 Query: 227 LGDPAEYAHLVQ 238 +P E A + Sbjct: 230 AQNPEEVAEVFL 241 >6CGE-A nrPDB Length = 328 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 61/252 (24%), Positives = 98/252 (38%), Gaps = 39/252 (15%) Query: 12 VAVITGGASGLGLSTAKRLVGQGA-----TAVLLDVPNSEGETEAKKL----GGNCIFAP 62 V +ITG +SG+GL A RL + A L D+ EA + G+ Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V K V AA E GR+DV V AG+ + ++ V + V++VN+ Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 116 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 +GT +++ M + G ++ T SV G Y ASK + G+ + Sbjct: 117 VGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTL---PDKVRN-------------FLASQVPFPSR 226 A L P G+ + I G T + + P++V + S+ F Sbjct: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREA 230 Query: 227 LGDPAEYAHLVQ 238 +P E A + Sbjct: 231 AQNPEEVAEVFL 242 >2YW9-A nrPDB Length = 261 Score = 132 bits (333), Expect = 1e-31, Method: Composition-based stats. Identities = 59/262 (22%), Positives = 102/262 (38%), Gaps = 21/262 (8%) Query: 7 SVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPN---SEGETEAKKLGGNCIFA 61 + G A++ G LG + A +L GA L E E A+ LGG + Sbjct: 5 DLSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGG-ALLF 63 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 A+VT ++E+ A KE FG +D V IA A + E + +D+ + V+ Sbjct: 64 RADVTQDEELDALFAGVKEAFGGLDYLV--HAIAFAPREAMEGRYIDTRRQDWLLALEVS 121 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 V R ++ + G I+ A+ + + +K + Sbjct: 122 AYSLVAVARRAEPLLRE--------GGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRY 173 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLP--DKVRNFLASQVPFPSRLGDPAEYAHLVQM 239 +A +L P G+RV I+ G T ++P K+ + +A P R E +L Sbjct: 174 LAYELGPKGVRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPL-RRNITQEEVGNLGLF 232 Query: 240 VIE--NPFLNGEVIRLDGAIRM 259 ++ + GEV+ +D + Sbjct: 233 LLSPLASGITGEVVYVDAGYHI 254 >1B15-A nrPDB Length = 254 Score = 127 bits (320), Expect = 5e-30, Method: Composition-based stats. Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 24/214 (11%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGAT-AVLLDV---PNSEGETEAKKLGGNCIFAP 62 + + G+GL T++ LV + V+LD P + E +A N F Sbjct: 2 DLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHT 61 Query: 63 ANVTSE-KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 +VT E + L ++ +D+ +N AGI +R I +N Sbjct: 62 YDVTVPVAESKKLLKKIFDQLKTVDILINGAGI--------------LDDHQIERTIAIN 107 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 G N + + +GG G+I N SV F YSASK +V T Sbjct: 108 FTGLVNTTTAILDFWDKR---KGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNS 164 Query: 182 IARDLAP-IGIRVVTIAPGLFATPLLTTLPDKVR 214 +A+ LAP G+ +I PG+ TPL+ T + Sbjct: 165 LAK-LAPITGVTAYSINPGITRTPLVHTFNSWLD 197 >3KZV-A nrPDB Length = 254 Score = 127 bits (319), Expect = 5e-30, Method: Composition-based stats. Identities = 37/207 (17%), Positives = 86/207 (41%), Gaps = 16/207 (7%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG--ETEAKKLGGNCIFAPANVT 66 G V ++TG + G+G S L V+ V SE + +K G + ++T Sbjct: 1 MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDIT 60 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + ++ + A + G+ID V AG+ ++ +E + ++++ ++N Sbjct: 61 EDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNE-----IDVNAWKKLYDINFFSIV 115 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 +++ + + + G ++ +S A AY +SK + + +A + Sbjct: 116 SLVGIALPELKKT-------NGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE- 167 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKV 213 ++ + +APG+ T + + + V Sbjct: 168 -ERQVKAIAVAPGIVDTDMQVNIRENV 193 >2HRB-A nrPDB Length = 274 Score = 122 bits (306), Expect = 2e-28, Method: Composition-based stats. Identities = 44/245 (17%), Positives = 81/245 (33%), Gaps = 65/245 (26%) Query: 11 LVAVITGGASGLGLSTAKRLVGQ-GATAVLLDVPNSEGETEAKKLGGNCI---FAPANVT 66 VA++TG G+GL+ A+ L Q VL + G+ ++L + F ++ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 62 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + ++A ++++G ++V VN A +A + + + N T Sbjct: 63 DLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKA------EMTLKTNFFATR 116 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTAS------------------------------- 155 N+ + +M G ++N +S Sbjct: 117 NMCNELLPIMK--------PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDL 168 Query: 156 -----------VAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI----GIRVVTIAPGL 200 V EG + Y SK G+ ++ +AR L I V PG Sbjct: 169 MKKFVEDTKNEVHEREGWPN-SPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGP 227 Query: 201 FATPL 205 T + Sbjct: 228 VKTDM 232 >3E9N-A nrPDB Length = 245 Score = 120 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 23/248 (9%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 S+K +AV+TG G+G+ K L L A+ G +++ Sbjct: 2 SLKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEG--VEPIESDIV 58 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E + + + +D V+ A +A + + ++ ++ +++N+I Sbjct: 59 KEVLEEGGVDK-LKNLDHVDTLVHAAAVA------RDTTIEAGSVAEWHAHLDLNVIVPA 111 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + R + + G +I S A G Y+ASK + G+ ++ Sbjct: 112 ELSRQLLPALRAA-------SGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEE 164 Query: 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFL 246 A GIRV T++PG TP+L L D ++ +P E A+ ++ VI+ Sbjct: 165 ANNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEI-----YIEPKEIANAIRFVIDAGET 219 Query: 247 NGEVIRLD 254 ++ +D Sbjct: 220 T-QITNVD 226 >1MG5-A nrPDB Length = 255 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 54/214 (25%), Positives = 81/214 (37%), Gaps = 24/214 (11%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLV-GQGATAVLLDV---PNSEGETEAKKLGGNCIFAP 62 ++ + G G+GL T+K L+ V+LD P + E +A F P Sbjct: 3 TLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYP 62 Query: 63 ANVTSE-KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 +VT E L + +DV +N AGI +R I VN Sbjct: 63 YDVTVPIAETTKLLKTIFAQLKTVDVLINGAGI--------------LDDHQIERTIAVN 108 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 G N + + +GG G+I N SV F YS +K +V T Sbjct: 109 YTGLVNTTTAILDFWDKR---KGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSS 165 Query: 182 IARDLAP-IGIRVVTIAPGLFATPLLTTLPDKVR 214 +A+ LAP G+ T+ PG+ T L+ + Sbjct: 166 LAK-LAPITGVTAYTVNPGITRTTLVHKFNSWLD 198 >3O26-A nrPDB Length = 311 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 55/309 (17%), Positives = 93/309 (30%), Gaps = 86/309 (27%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----NCIFAPAN 64 K AV+TGG G+G K+L G VL ++G +KL N +F + Sbjct: 11 KRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLD 70 Query: 65 VTSE-KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHE-------------------- 103 VT + + K FG++D+ VN AG+A Sbjct: 71 VTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYE 130 Query: 104 ----KKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAA- 158 ++ T E + + +N G +V ++ ++ ++ I+N +S Sbjct: 131 KPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSP------RIVNVSSSTGS 184 Query: 159 -----------------------------------------FEGQVG-QAAYSASKGGIV 176 G AAY+ SK + Sbjct: 185 LKYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLN 244 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQV------PFPSRLGDP 230 T +A + V + PGL T + + + A V P G Sbjct: 245 AYTRVLANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALFPDDGPSGFF 302 Query: 231 AEYAHLVQM 239 + + L Sbjct: 303 YDCSELSAF 311 >5L51-A nrPDB Length = 324 Score = 117 bits (294), Expect = 5e-27, Method: Composition-based stats. Identities = 55/274 (20%), Positives = 84/274 (30%), Gaps = 87/274 (31%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG----ETEAKKLGGN----CIFAP 62 AV+TG G+G K+L +G T +L G E K+LG + Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGI--------------------------AV 96 +V V A + K KFG +D+ VN AG+ A Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSGAA 135 Query: 97 AIKTYHEK--KNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTA 154 + YH K V T+E + I N G+ V + ++ Q++ I+N + Sbjct: 136 KTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSP------RIVNVS 189 Query: 155 SVAAFEGQ-------------------------------------------VGQAAYSAS 171 S + +AY S Sbjct: 190 STLSSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVS 249 Query: 172 KGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205 K + T IA+ R+ + PG T L Sbjct: 250 KAALNAYTRIIAKKYPSF--RINAVCPGYTKTDL 281 >5PGZ-A nrPDB Length = 276 Score = 113 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 73/203 (35%), Gaps = 19/203 (9%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPA 63 ++G ++TG + G+G A L GA VL + + + + Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 + + + A + G +D+ + ++ +H+ + V +RV+ VN + Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSV------RRVMEVNFL 129 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + ++ Q+ G I +S+A Q A YSASK + G I Sbjct: 130 SYVVMSTAALPMLKQS-------NGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIR 182 Query: 184 RDLAPIGIRVVTIAP--GLFATP 204 +L + V GL T Sbjct: 183 TELYITKVNVSITLCVLGLIDTE 205 >3DWF-A nrPDB Length = 276 Score = 113 bits (283), Expect = 7e-26, Method: Composition-based stats. Identities = 33/203 (16%), Positives = 68/203 (33%), Gaps = 19/203 (9%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPA 63 ++G ++TG + G+G A L GA V+ + + + + Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 ++ + + A G +D+ + Y+ +++ ++ + VN Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNH------VLYNRLTFFHGEIDNVRKSMEVNFH 122 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + ++ Q++ G I +SVA A YSASK + G + Sbjct: 123 SFVVLSVAAMPMLMQSQ-------GSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLR 175 Query: 184 RDLAPIGIRVVTIAP--GLFATP 204 + + V GL T Sbjct: 176 SEFLVNKVNVSITLCILGLIDTE 198 >1N5D-A nrPDB Length = 288 Score = 113 bits (283), Expect = 8e-26, Method: Composition-based stats. Identities = 44/244 (18%), Positives = 80/244 (32%), Gaps = 63/244 (25%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGA-TAVLLDVPNSEGETEAKKLGGNCI---FAPANVT 66 VA++TG G+G + + L Q A VL + G+ K+L + F ++ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + ++A ++++G +DV VN A IA + Q + + N +GT Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQA------ELTMKTNFMGTR 118 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG------------------------- 161 NV + ++ G ++N +S Sbjct: 119 NVCTELLPLIKPQ--------GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGL 170 Query: 162 ----------------QVGQAAYSASKGGIVGMTLPIARDL----APIGIRVVTIAPGLF 201 + Y +K G+ ++ AR L A I + PG Sbjct: 171 MNKFVEDTKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWV 230 Query: 202 ATPL 205 T + Sbjct: 231 RTDM 234 >3OIG-A nrPDB Length = 266 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 48/264 (18%), Positives = 90/264 (34%), Gaps = 21/264 (7%) Query: 7 SVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG----GNCIF 60 S++G V+ G A + A+ L GA + ++ + G + I Sbjct: 4 SLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSII 63 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 P +VT++ E++ KE+ G I +C IA A K + + F N+ Sbjct: 64 LPCDVTNDAEIETCFASIKEQVGVIHGIAHC--IAFANKEELVGEYLNTNRDGFLLAHNI 121 Query: 121 NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180 + V++ +M + G I+ + +K + Sbjct: 122 SSYSLTAVVKAARPMMTE--------GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVK 173 Query: 181 PIARDLAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYAHLVQ 238 +A DL IRV +I+ G T + D + + + P R P E Sbjct: 174 YLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPL-RRTTTPEEVGDTAA 232 Query: 239 MVIENPF--LNGEVIRLDGAIRMQ 260 + + + GE + +D + Sbjct: 233 FLFSDMSRGITGENLHVDSGFHIT 256 >4M89-A nrPDB Length = 261 Score = 112 bits (280), Expect = 2e-25, Method: Composition-based stats. Identities = 45/261 (17%), Positives = 89/261 (34%), Gaps = 19/261 (7%) Query: 8 VKGLVAVITG--GASGLGLSTAKRLVGQGATAV---LLDVPNSEGETEAKKLGGNCIFAP 62 ++G +ITG + AK QGA ++D A +L +F Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVF-R 62 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V S+ E+ + + +D V+ G A + + + + E F ++ Sbjct: 63 CDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSI-SREAFNTAHEISA 121 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + +M G+ I+ + + A +K + Sbjct: 122 YSLPALAKAARPMM-------RGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFT 174 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYAHLVQMV 240 A L GIR I+ G T + + D K+ +A+ P R E + + Sbjct: 175 AACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPL-RRNVTIEEVGNTAAFL 233 Query: 241 IEN--PFLNGEVIRLDGAIRM 259 + + + GE+ +DG + Sbjct: 234 LSDLSSGITGEITYVDGGYSI 254 >5YCX-A nrPDB Length = 266 Score = 111 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 50/267 (18%), Positives = 92/267 (34%), Gaps = 23/267 (8%) Query: 4 AVRSVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-----GG 56 ++ ++G V+ G A + A+ L GA + E ++L G Sbjct: 2 SMELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTY-AGERLERNVRELADTLEGQ 60 Query: 57 NCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 + P +VT+++E+ A K++ G I +C IA A + + + + + F Sbjct: 61 ESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHC--IAFANRDDLKGEFVDTSRDGFLL 118 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 N++ V R VM + G I+ + +K + Sbjct: 119 AQNISAFSLTAVAREAKKVMTE--------GGNILTLTYLGGERVVKNYNVMGVAKASLE 170 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYA 234 +A DL GIRV I+ G T + D + + + P R E Sbjct: 171 ASVKYLANDLGQHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPL-RRTTTQEEVG 229 Query: 235 HLVQMVIENPF--LNGEVIRLDGAIRM 259 + + + GE I +D + Sbjct: 230 DTAVFLFSDLARGVTGENIHVDSGYHI 256 >5KOI-A nrPDB Length = 293 Score = 111 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 51/260 (19%), Positives = 96/260 (36%), Gaps = 18/260 (6%) Query: 8 VKGLVAVITGGASGLGLS--TAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAP 62 ++G +I G A+ L+ AK+L QGA ++ G+ A+++G + + P Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFV-LP 84 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V V A ++K+G +D V+ G + + + V T E+F R + ++ Sbjct: 85 CDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTE-LKGRYADVTTRENFSRTMVISA 143 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 V + +M G I+ + +K + M + Sbjct: 144 YSFTEVAQRAEKLMKD--------GGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYL 195 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNF-LASQVPFPSRLGDPAEYAHLVQMVI 241 A D P GIRV I+ G T + D F + R D + ++ Sbjct: 196 AADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLL 255 Query: 242 EN--PFLNGEVIRLDGAIRM 259 + + GE+ +D + Sbjct: 256 SDLSSGVTGEIHFVDSGYNI 275 >5TF4-A nrPDB Length = 274 Score = 110 bits (275), Expect = 6e-25, Method: Composition-based stats. Identities = 45/267 (16%), Positives = 87/267 (32%), Gaps = 19/267 (7%) Query: 1 MAAAVRSVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLG 55 MA + G +I G A + AK GA + E A+++ Sbjct: 3 MAKGNGLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVK 62 Query: 56 GNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ 115 G + +V+ + A ++K+G++D V I + K + + +F Sbjct: 63 G-FVCGHCDVSDSASIDAVFNTIEKKWGKLDFLV--HAIGFSDKEELSGRYVDISESNFM 119 Query: 116 RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 +N+++ + + +M G I+ A + +K + Sbjct: 120 MTMNISVYSLTALTKRAEKLMSD--------GGSILTLTYYGAEKVVPNYNVMGVAKAAL 171 Query: 176 VGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYA 234 +A DL P IRV I+ G T + + D + R E Sbjct: 172 EASVKYLAVDLGPKHIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVG 231 Query: 235 HLVQMVIEN--PFLNGEVIRLDGAIRM 259 ++ + + GEV +D + Sbjct: 232 DSALYLLSDLSRSVTGEVHHVDSGYNI 258 >3BHI-A nrPDB Length = 276 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 44/244 (18%), Positives = 84/244 (34%), Gaps = 65/244 (26%) Query: 12 VAVITGGASGLGLSTAKRLVG--QGATAVLLDVPNSEGETEAKKLGGNCI---FAPANVT 66 VA++TGG G+GL+ + L G VL + G+ ++L + F ++ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSG-DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 64 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + ++A ++++G +DV VN AGIA + Q + + N GT Sbjct: 65 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA------EVTMKTNFFGTR 118 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEG------------------------- 161 +V + ++ G ++N +S+ + Sbjct: 119 DVCTELLPLIKPQ--------GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGL 170 Query: 162 ----------------QVGQAAYSASKGGIVGMTLPIARDLAPI----GIRVVTIAPGLF 201 +AY +K G+ ++ AR L+ I + PG Sbjct: 171 MNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWV 230 Query: 202 ATPL 205 T + Sbjct: 231 RTDM 234 >4NR0-A nrPDB Length = 273 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 44/267 (16%), Positives = 92/267 (34%), Gaps = 22/267 (8%) Query: 8 VKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----NCIFA 61 + G A+I G AS + A + +GA + + G + Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 Query: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 P +V + +++A + + +D+ V+ G A + + V T E F+ +++ Sbjct: 64 PCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFT-AVTTREGFRIAHDIS 122 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 + + +M G+ G ++ + + A +K + Sbjct: 123 AYSFIALAKAGREMMK-------GRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRY 175 Query: 182 IARDLAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYAHLVQM 239 +A L G RV ++ G T + + K+ Q P R E + Sbjct: 176 LAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPL-RRNVTIEEVGNAGAF 234 Query: 240 VIEN--PFLNGEVIRLDGAI---RMQP 261 + + ++GE++ +DG M P Sbjct: 235 LCSDLASGISGEILYVDGGFNTTAMGP 261 >3GRK-A nrPDB Length = 293 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 47/267 (17%), Positives = 86/267 (32%), Gaps = 19/267 (7%) Query: 1 MAAAVRSVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLG 55 M A ++G +I G A + AK GA ++ E A++LG Sbjct: 22 MTAQSGLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELG 81 Query: 56 GNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ 115 + +V + A ++K+G++D V I + K + + +F Sbjct: 82 A-FVAGHCDVADAASIDAVFETLEKKWGKLDFLV--HAIGFSDKDELTGRYIDTSEANFT 138 Query: 116 RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 + +++ V R +M G I+ A + +K + Sbjct: 139 NTMLISVYSLTAVSRRAEKLMAD--------GGSILTLTYYGAEKVMPNYNVMGVAKAAL 190 Query: 176 VGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYA 234 +A DL P IRV I+ G T + + D + R E Sbjct: 191 EASVKYLAVDLGPQNIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVG 250 Query: 235 HLVQMVIEN--PFLNGEVIRLDGAIRM 259 + + + + GEV D + Sbjct: 251 DVGLYFLSDLSRSVTGEVHHADSGYHV 277 >1FJH-A nrPDB Length = 257 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 63/283 (22%), Positives = 106/283 (37%), Gaps = 68/283 (24%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 VI+G A+G+G +T K L G V +D+ ++E A++++ + + Sbjct: 5 VISGCATGIGAATRKVLEAAGHQIVGIDIRDAE--------------VIADLSTAEGRKQ 50 Query: 74 ALTLAKEK-FGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 A+ K +D V CAG+ K V++VN G ++ Sbjct: 51 AIADVLAKCSKGMDGLVLCAGLGPQTKVLGN-------------VVSVNYFGATELMDAF 97 Query: 133 AGVMGQNEPDQGGQRGVIINTASVAAFE----------------------------GQVG 164 + + G + + +SVA+ Q G Sbjct: 98 LPALKK------GHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGG 151 Query: 165 QAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVR--NFLASQVP 222 AY+ SK + A G+R+ TIAPG TPLL R +A VP Sbjct: 152 NLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVP 211 Query: 223 FPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGAIR--MQP 261 R +P+E A ++ ++ +++G I +DG I M+P Sbjct: 212 PMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGIDAVMRP 254 >5CFZ-A nrPDB Length = 305 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 40/260 (15%), Positives = 90/260 (34%), Gaps = 18/260 (6%) Query: 8 VKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLGGNCIFAP 62 + G ++TG AS + A+ + +GA + E A +LG + + Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQ 105 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V + + + + + D V+ G A + + N V T E F+ +++ Sbjct: 106 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAV-TREGFKIAHDISS 164 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + ++ ++ + + A +K + + Sbjct: 165 YSFVAMAKACRSMLN--------PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYM 216 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 A + P G+RV I+ G T + + D + V R + + + Sbjct: 217 ANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 276 Query: 242 EN--PFLNGEVIRLDGAIRM 259 + ++GEV+ +DG + Sbjct: 277 SDLSAGISGEVVHVDGGFSI 296 >4JQC-A nrPDB Length = 282 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 40/265 (15%), Positives = 92/265 (34%), Gaps = 18/265 (6%) Query: 3 AAVRSVKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLGGN 57 + + + G ++TG AS + A+ + +GA + E A +LG + Sbjct: 19 SHMGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD 78 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 + +V + + + + + D V+ G A + + N V T E F+ Sbjct: 79 IV-LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAV-TREGFKIA 136 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVG 177 +++ + + ++ ++ + + A +K + Sbjct: 137 HDISSYSFVAMAKACRSMLN--------PGSALLTLSYLGAERAIPNYNVMGLAKASLEA 188 Query: 178 MTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYAHL 236 +A + P G+RV I+ G T + + D + V R + + Sbjct: 189 NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNS 248 Query: 237 VQMVIEN--PFLNGEVIRLDGAIRM 259 + + ++GEV+ +DG + Sbjct: 249 AAFLCSDLSAGISGEVVHVDGGFSI 273 >2DKN-A nrPDB Length = 255 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 57/257 (22%), Positives = 96/257 (37%), Gaps = 22/257 (8%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN--CIFAPAN----V 65 V ITG ASG+G + + L G T + +D ++ E + GG + A + V Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGRETAVAAVLDRCGGV 62 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 A + + G + VAVN G++ + E ++ ++G+ Sbjct: 63 LDGLVCCAGVGVTAANSGLV-VAVNYFGVSALLDGLAEALSRGQQPAAV-------IVGS 114 Query: 126 FNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185 + A + E G I A AY+ SK + + D Sbjct: 115 IAATQPGAAELPMVEAMLAGDEARAIELAEQQGQT----HLAYAGSKYAVTCLARRNVVD 170 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLPDKVR--NFLASQVPFPSRLGDPAEYAHLVQMVI-- 241 A G+R+ +APG TPLL R V R +P E A + ++ Sbjct: 171 WAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEPREVAEAIAFLLGP 230 Query: 242 ENPFLNGEVIRLDGAIR 258 + F++G V+ +DG + Sbjct: 231 QASFIHGSVLFVDGGMD 247 >3K2E-A nrPDB Length = 296 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 45/260 (17%), Positives = 86/260 (33%), Gaps = 19/260 (7%) Query: 8 VKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPN---SEGETEAKKLGGNCIFAP 62 ++G VI G A L AK + QGA L + + A+ LG + P Sbjct: 28 MEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVK-LTVP 86 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V+ + V + E++G +D V +A + K + + +L +F ++++ Sbjct: 87 CDVSDAESVDNMFKVLAEEWGSLDFVV--HAVAFSDKNELKGRYVDTSLGNFLTSMHISC 144 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + +M G I+ + A + K + + Sbjct: 145 YSFTYIASKAEPLMT--------NGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYL 196 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 A DL IRV I+ G T + + D R + ++ Sbjct: 197 AVDLGKQQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLL 256 Query: 242 EN--PFLNGEVIRLDGAIRM 259 + GE + +D + Sbjct: 257 SDLGRGTTGETVHVDCGYHV 276 >4ZJU-A nrPDB Length = 275 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 40/257 (15%), Positives = 85/257 (33%), Gaps = 15/257 (5%) Query: 8 VKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVPNSEGET--EAKKLGGNCIFAPA 63 + G +I G AS + A+ L +GA + E + G+ + P Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVFPC 73 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + E+ A + + +D V+ G A A + + V + F+ +++ Sbjct: 74 DVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTD-VTDRDGFKIAHDISAY 132 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + R ++ ++G ++ + +K + +A Sbjct: 133 SFVAMARAAKPLLQ-------ARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLA 185 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 L GIRV I+ G T + + + +V R E + + Sbjct: 186 SSLGVDGIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLCS 245 Query: 243 --NPFLNGEVIRLDGAI 257 + GE++ +D Sbjct: 246 PWASGITGEILYVDAGF 262 >1SNY-A nrPDB Length = 267 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 40/207 (19%), Positives = 68/207 (32%), Gaps = 20/207 (9%) Query: 14 VITGGASGLGLSTAKRLV---GQGATAVLLDVPNSEGETEAKKLGG--NCIFAPANVTSE 68 +ITG GLGL K L+ + + N ++ + Sbjct: 25 LITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRNF 84 Query: 69 KEVQAALTLA--KEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + K ++V N AGIA ++Q + N + Sbjct: 85 DAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELL-----DTLQTNTVVPI 139 Query: 127 NVIRLVAGVMGQNEPD-----QGGQRGVIINTASVAA-FEGQ--VGQAAYSASKGGIVGM 178 + + ++ + G R IIN +S+ +G G AY SK + Sbjct: 140 MLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAA 199 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPL 205 T ++ DL P I V++ PG T + Sbjct: 200 TKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >5I9N-A nrPDB Length = 276 Score = 104 bits (261), Expect = 3e-23, Method: Composition-based stats. Identities = 40/258 (15%), Positives = 89/258 (34%), Gaps = 18/258 (6%) Query: 8 VKGLVAVITG--GASGLGLSTAKRLVGQGATAVLLDVPN--SEGETEAKKLGGNCIFAPA 63 + G ++TG + AK +GA V + + TE G+ + P Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPC 63 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + ++ A K + +D V+ G A + T E+F+ +++ Sbjct: 64 DVADDAQIDALFASLKTHWDSLDGLVHSIGFA-PREAIAGDFLDGLTRENFRIAHDISAY 122 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 + + ++ + ++ + + A +K + +A Sbjct: 123 SFPALAKAALPMLSDD--------ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLA 174 Query: 184 RDLAPIGIRVVTIAPGLFATPLLTTLPD--KVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 L G+RV I+ G T + + K+ +F+ S P R + + ++ Sbjct: 175 VSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPL-KRNVTIEQVGNAGAFLL 233 Query: 242 EN--PFLNGEVIRLDGAI 257 + + EV+ +D Sbjct: 234 SDLASGVTAEVMHVDSGF 251 >4ALL-A nrPDB Length = 277 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 48/265 (18%), Positives = 81/265 (30%), Gaps = 21/265 (7%) Query: 4 AVRSVKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGN 57 + +++ VI G A + AK L GA V + K L Sbjct: 21 HMLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPE 80 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 +V S++EV + G ID IA A + + E F Sbjct: 81 AHLYQIDVQSDEEVINGFEQIGKDVGNIDGVY--HSIAFANMEDLRGRFSETSREGFLLA 138 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVG 177 +++ V +M + G I+ T + +K + Sbjct: 139 QDISSYSLTIVAHEAKKLMPE--------GGSIVATTYLGGEFAVQNYNVMGVAKASLEA 190 Query: 178 MTLPIARDLAPIGIRVVTIAPGLFATPLLTTLP--DKVRNFLASQVPFPSRLGDPAEYAH 235 +A DL P IRV I+ G T + + + + + P R D E Sbjct: 191 NVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPL-KRNVDQVEVGK 249 Query: 236 LVQMVIEN--PFLNGEVIRLDGAIR 258 ++ + + GE I +D Sbjct: 250 TAAYLLSDLSSGVTGENIHVDSGFH 274 >3UCF-A nrPDB Length = 223 Score = 101 bits (252), Expect = 3e-22, Method: Composition-based stats. Identities = 50/248 (20%), Positives = 88/248 (35%), Gaps = 39/248 (15%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 V V+ GG SG+G AK+L + T V + + +++ EK V Sbjct: 8 VYVVLGGTSGIGAELAKQLESE-HTIVHVASRQTGL----------------DISDEKSV 50 Query: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRL 131 G D + AG + + + + G + Sbjct: 51 YHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQA-----KYAFDTKFWGAVLAAKH 101 Query: 132 VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 A + Q G I T+ + + + +A I T +A++LAP I Sbjct: 102 GARYLKQ--------GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--I 151 Query: 192 RVVTIAPGLFATPLLTTLPDKVRNFLASQVP---FPSRLGDPAEYAHLVQMVIENPFLNG 248 RV I+PGL T + R+ + + ++G+ ++ A I+N ++ G Sbjct: 152 RVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAYLFAIQNSYMTG 211 Query: 249 EVIRLDGA 256 VI +DG Sbjct: 212 TVIDVDGG 219 >4J3F-A nrPDB Length = 280 Score = 100 bits (249), Expect = 8e-22, Method: Composition-based stats. Identities = 42/264 (15%), Positives = 86/264 (32%), Gaps = 18/264 (6%) Query: 3 AAVRSVKGLVAVITG--GASGLGLSTAKRLVGQGATAVLLDVPN--SEGETEAKKLGGNC 58 + + + G +ITG + AK + +GA V E + Sbjct: 19 SHMGFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEF-NPA 77 Query: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVH-TLEDFQRV 117 P +V S++E++ + + +D V IA A + E T E F Sbjct: 78 AVLPCDVISDQEIKDLFVELGKVWDGLDAIV--HSIAFAPRDQLEGNFIDCVTREGFSIA 135 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVG 177 +++ + + +M + ++ + A + +K + Sbjct: 136 HDISAYSFAALAKEGRSMMKN-------RNASMVALTYIGAEKAMPSYNTMGVAKASLEA 188 Query: 178 MTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPD-KVRNFLASQVPFPSRLGDPAEYAHL 236 A L GI+V ++ G T + + + K + V + D E + Sbjct: 189 TVRYTALALGEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNT 248 Query: 237 VQMVIENPF--LNGEVIRLDGAIR 258 V + + + GEV+ +D Sbjct: 249 VAFLCSDMATGITGEVVHVDAGYH 272 >4HWK-A nrPDB Length = 288 Score = 96.5 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 46/222 (20%), Positives = 83/222 (37%), Gaps = 29/222 (13%) Query: 4 AVRSVKG----LVAVITGGASGLGL---STAKRLVGQGATAVLLDVPNSEGETEAKKLGG 56 VR+++G V ++TG + G G L+ G+ VL + +LG Sbjct: 24 GVRTMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGA 83 Query: 57 -----NCIFAPANVTSEKEVQAALTLAKEK-----FGRIDVAVNCAG-IAVAIKTYHEKK 105 + PA++ +E +Q L +E R+ + +N AG + K + + Sbjct: 84 ERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLS 142 Query: 106 NQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQ 165 + + +NL + V PD G ++N +S+ A + G Sbjct: 143 DSTQVNNYW----ALNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGW 194 Query: 166 AAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLT 207 A Y A K + +A + +RV+ APG T + Sbjct: 195 ALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQ 234 >4Z3K-A nrPDB Length = 275 Score = 95.7 bits (237), Expect = 2e-20, Method: Composition-based stats. Identities = 43/210 (20%), Positives = 77/210 (36%), Gaps = 25/210 (11%) Query: 12 VAVITGGASGLGL---STAKRLVGQGATAVLLDVPNSEGETEAKKLGG-----NCIFAPA 63 V ++TG + G G L+ G+ VL + +LG + PA Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 64 NVTSEKEVQAALTLAKEK-----FGRIDVAVNCAG-IAVAIKTYHEKKNQVHTLEDFQRV 117 ++ +E +Q L +E R+ + +N AG + K + + + + Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYW--- 138 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVG 177 +NL + V PD G ++N +S+ A + G A Y A K Sbjct: 139 -ALNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 193 Query: 178 MTLPIARDLAPIGIRVVTIAPGLFATPLLT 207 + +A + +RV+ APG T + Sbjct: 194 LFQVLALE--EPNVRVLNYAPGPLDTDMQQ 221 >4NK4-A nrPDB Length = 301 Score = 93.4 bits (231), Expect = 9e-20, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 90/266 (33%), Gaps = 17/266 (6%) Query: 1 MAAAVRSVKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVPNSEGETE-AKKLGGN 57 M + +KG +I G A+ + AK L GA S G+ L + Sbjct: 32 MGRMINILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVD 91 Query: 58 CIF-APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQR 116 F P NV + KE++ +D V IA + K + ++F + Sbjct: 92 SDFMIPCNVEDPSSMDLLFERIKERWETLDFVV--HSIAFSDKNELRGPYYNTSRDNFIQ 149 Query: 117 VINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIV 176 + V+ ++R A +M G +I + A + +K + Sbjct: 150 TMLVSCFSFTEIVRRAAQLMPH--------GGAMITLTYGGSMRVVPNYNAMAPAKSALE 201 Query: 177 GMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVR-NFLASQVPFPSRLGDPAEYAH 235 T +A D + IR+ I+ G T ++ + + + R + + Sbjct: 202 SSTKYLACDYGGMNIRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGN 261 Query: 236 LVQMVIE--NPFLNGEVIRLDGAIRM 259 ++ + + GE+ +D + Sbjct: 262 SALYLLSYLSNGVTGEIHYVDCGYNI 287 >5LCX-A nrPDB Length = 316 Score = 90.7 bits (224), Expect = 6e-19, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 45/114 (39%), Gaps = 7/114 (6%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-------GGNCIFAPA 63 A++TG G+G ++L +G +L G +KL +F Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 +VT V A K KFG++D+ VN AG++ + DF+ + Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKAL 121 >1OAA-A nrPDB Length = 259 Score = 89.9 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 40/217 (18%), Positives = 80/217 (36%), Gaps = 23/217 (10%) Query: 12 VAVITGGASGLGLSTAKRLVGQ---GATAVLLDVPNSEGETEAKKLGG-----NCIFAPA 63 V V+TG + G G + A +L G+ ++ S ++LG + A A Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 64 NVTSEKEVQAALTLAKEK-----FGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 ++ +E VQ L+ +E R+ + +N A + + V+ L + Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAA---TLGDVSKGFLNVNDLAEVNNYW 123 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 +NL + + G ++N +S+ A + G Y A K + Sbjct: 124 ALNLTSMLCLTSGTLNAFQDSP----GLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 179 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRN 215 +A + +RV++ APG + + ++ Sbjct: 180 YQVLAAE--EPSVRVLSYAPGPLDNDMQQLARETSKD 214 >3U9L-A nrPDB Length = 324 Score = 89.2 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 50/202 (24%), Positives = 84/202 (41%), Gaps = 21/202 (10%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAV-----LLDVPNSEGETE---AKKLGGNCIFAP 62 + +ITG +SG G TA+ L G G ++ S E A+ + Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRTLE 65 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V S+ V A+ + GRIDV ++ AG + T E F + ++N+ Sbjct: 66 LDVQSQVSVDRAIDQIIGEDGRIDVLIHNAG------HMVFGPAEAFTPEQFAELYDINV 119 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQ-AAYSASKGGIVGMTLP 181 + T V R M + + G++I +S ++ G A Y A+K + + + Sbjct: 120 LSTQRVNRAALPHMRRQ------KHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQ 173 Query: 182 IARDLAPIGIRVVTIAPGLFAT 203 AR+L+ GI I PG F + Sbjct: 174 YARELSRWGIETSIIVPGAFTS 195 >2PD3-A nrPDB Length = 275 Score = 88.8 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 42/260 (16%), Positives = 91/260 (35%), Gaps = 19/260 (7%) Query: 8 VKGLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNS---EGETEAKKLGGNCIFAP 62 +KG +I G A + A+ QGAT + S A++L ++ Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVY-E 62 Query: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 +V+ E+ ++ K+ G +D V +A A K E + F + +++ Sbjct: 63 LDVSKEEHFKSLYNSVKKDLGSLDFIV--HSVAFAPKEALEGSLLETSKSAFNTAMEISV 120 Query: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 + + ++ ++ + + + + +K + + Sbjct: 121 YSLIELTNTLKPLLN--------NGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYL 172 Query: 183 ARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDP-AEY--AHLVQM 239 A DL IRV ++ G T + + D +++ P R E A + + Sbjct: 173 AVDLGKHHIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLL 232 Query: 240 VIENPFLNGEVIRLDGAIRM 259 + ++GEV +D + Sbjct: 233 SSLSSGVSGEVHFVDAGYHV 252 >5WQO-A nrPDB Length = 234 Score = 88.0 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 69/199 (34%), Gaps = 20/199 (10%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVP---NSEGETEAKKLGGNCIFAPANVTSEK 69 +I G + G+GL A + +GA + + + A++ G ++ Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 Query: 70 EVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 + + E+ RID + AGI ++ E ++ N I + Sbjct: 69 CAERIGEMLGER--RIDRLIVNAGIYGP----QQQDVAEIDAEQTAQLFLTNAIAPLRLA 122 Query: 130 RLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA---YSASKGGIVGMTLPIARDL 186 R ++G + + GV+ +S A A Y ASK + + + Sbjct: 123 RALSG--------RVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEF 174 Query: 187 APIGIRVVTIAPGLFATPL 205 + ++ + PG T + Sbjct: 175 EELPFSLLLLHPGWVRTEM 193 >5TQV-A nrPDB Length = 233 Score = 87.6 bits (216), Expect = 5e-18, Method: Composition-based stats. Identities = 30/195 (15%), Positives = 71/195 (36%), Gaps = 15/195 (7%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 +I G + GLG ++ G + ++ + LG + ++T ++ Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAAL-RALGAHAHAL--DITQPEQ 66 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 + A + R+DVAV +G+ + + +DF V++ N+ G ++ Sbjct: 67 IAALGWKLDGE--RLDVAVVVSGVYGP----RTEGVETIASDDFDTVMHTNVRGPMQLLP 120 Query: 131 LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIG 190 ++ ++ + + + G + Y ASK + + + L Sbjct: 121 ILLPLVEDARGVLAVVSSRMGSISEATGTTGWL----YRASKAALNDVLRIAS--LQTRH 174 Query: 191 IRVVTIAPGLFATPL 205 +++ PG T + Sbjct: 175 AACISLHPGWVRTDM 189 >4Q9N-A nrPDB Length = 298 Score = 86.9 bits (214), Expect = 8e-18, Method: Composition-based stats. Identities = 51/300 (17%), Positives = 104/300 (34%), Gaps = 57/300 (19%) Query: 7 SVKGLVAVITGGAS--GLGLSTAKRLVGQGATAVL---------------LDVPNSEGET 49 + G +A I G G G AK L GAT ++ L N+ E Sbjct: 5 DLTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASREL 64 Query: 50 EAKKLGGNCIFAPANVT--SEKE------------------VQAALTLAKEKFGRIDVAV 89 +L P + + + ++ V + K+ FG ID+ V Sbjct: 65 SNGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILV 124 Query: 90 NCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 + ++A K + + + ++ + +++ +M + G Sbjct: 125 H----SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM-----NAGASTIS 175 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-GIRVVTIAPGLFATPLLTT 208 + AS+ A G G A+K + T +A + G+RV TI+ G A+ Sbjct: 176 LTYLASMRAVPGYGGGMN--AAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKA 233 Query: 209 LP--DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGA---IRMQP 261 + +++ ++ P PS + + + ++ + GE + +D + + P Sbjct: 234 IGFIERMVDYYQDWAPLPSPM-EAEQVGAAAAFLVSPLASAITGETLYVDHGANVMGIGP 292 >2NTV-A nrPDB Length = 268 Score = 83.4 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 45/276 (16%), Positives = 91/276 (32%), Gaps = 36/276 (13%) Query: 8 VKGLVAVITG--GASGLGLSTAKRLVGQGATAVLLDVPNSEG-ETEAKKLGGNCIFAPAN 64 ++G +++G S + AK GA VL + A +L + Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIELD 63 Query: 65 VTSEKEVQAALTLAKEKFG---RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 V +E+ + + G ++D V+ G + + ED + I+++ Sbjct: 64 VQNEEHLATLAERVTAEIGEGNKLDGVVHSIG-FMPQTGMGTNQFFDAPYEDVSKGIHIS 122 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYS---ASKGGIVGM 178 ++ + + +M G I+ F+ AY+ +K + + Sbjct: 123 TYSYASLAKALLLIMN--------SGGSIVGM----DFDPTRAMPAYNWMTVAKSALESV 170 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTL------------PDKVRNFLASQVPFPSR 226 +AR+ G+R +A G T ++ + + + P Sbjct: 171 NRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWN 230 Query: 227 LGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 + DP A V ++ P G +I DG Q Sbjct: 231 MKDPTPVAKTVCALLSEWLPATTGSIIYADGGASTQ 266 >1ENP-A nrPDB Length = 312 Score = 81.9 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 53/293 (18%), Positives = 98/293 (33%), Gaps = 54/293 (18%) Query: 7 SVKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLD----------------------V 42 ++G A I G A G G + AK L GA ++ + Sbjct: 15 DLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVL 74 Query: 43 PNSEGETEAKKLGGNCIF-----APANV--------TSEKEVQAALTLAKEKFGRIDVAV 89 P+ K + +F P +V +S VQ A ++ FG ID+ V Sbjct: 75 PDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILV 134 Query: 90 NCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 + ++A K + + + I+ + +++ +M + GG Sbjct: 135 H----SLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM-----NPGGASIS 185 Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-GIRVVTIAPGLFATPLLTT 208 + AS G G S++K + T +A + IRV TI+ G + Sbjct: 186 LTYIASERIIPGYGGGM--SSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKA 243 Query: 209 LP--DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGAI 257 + D + + + P L E + ++ + G I +D + Sbjct: 244 IGFIDTMIEYSYNNAPIQKTL-TADEVGNAAAFLVSPLASAITGATIYVDNGL 295 >4OYR-A nrPDB Length = 289 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 44/276 (15%), Positives = 92/276 (33%), Gaps = 36/276 (13%) Query: 8 VKGLVAVITG--GASGLGLSTAKRLVGQGATAVLLDVPNSEG-ETEAKKLGGNCIFAPAN 64 + G +++G S + A+ QGA VL + +L + Sbjct: 25 LDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELD 84 Query: 65 VTSEKEVQAALTLAKEKFG---RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 V +E+ + + E G ++D V+ G + D + I+++ Sbjct: 85 VQNEEHLASLAGRVTEAIGAGNKLDGVVHSIG-FMPQTGMGINPFFDAPYADVSKGIHIS 143 Query: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYS---ASKGGIVGM 178 ++ + + +M G I+ F+ AY+ +K + + Sbjct: 144 AYSYASMAKALLPIMN--------PGGSIVGM----DFDPSRAMPAYNWMTVAKSALESV 191 Query: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLT-----TLPDK-------VRNFLASQVPFPSR 226 +AR+ G+R +A G T ++ L ++ + + P Sbjct: 192 NRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWN 251 Query: 227 LGDPAEYAHLVQMVIEN--PFLNGEVIRLDGAIRMQ 260 + D A V ++ + P G++I DG Q Sbjct: 252 MKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQ 287 >2O2S-A nrPDB Length = 315 Score = 77.2 bits (189), Expect = 6e-15, Method: Composition-based stats. Identities = 43/300 (14%), Positives = 90/300 (30%), Gaps = 60/300 (20%) Query: 7 SVKGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVP----------NSEGETEAKKL 54 ++G A + G A G G + AK L GA L P S E +KL Sbjct: 6 DLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKL 65 Query: 55 GGNCIF-----------------APANVTSEK--------EVQAALTLAKEKFGRIDVAV 89 + P ++ K ++ K+ G ID+ V Sbjct: 66 PDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILV 125 Query: 90 NCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 + ++A K + + + + + ++++ +M + G Sbjct: 126 H----SLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNE--------GGS 173 Query: 150 IINTASVAAFEGQVGQAA-YSASKGGIVGMTLPIARDLA-PIGIRVVTIAPGLFATPLLT 207 + + +AA G S++K + T +A + G+RV I+ G + + Sbjct: 174 AVTLSYLAAERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAAS 233 Query: 208 TLPDKVRNFLASQVP-------FPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGAIR 258 + R + ++ ++G + +D + Sbjct: 234 AIGKSGEKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLH 293 >2PTG-A nrPDB Length = 319 Score = 70.3 bits (171), Expect = 8e-13, Method: Composition-based stats. Identities = 42/313 (13%), Positives = 95/313 (30%), Gaps = 73/313 (23%) Query: 7 SVKGLVAVITGG--ASGLGLSTAKRLVGQGATAVLLDVP--------------------- 43 ++G A + G ++G G + K L GA ++ P Sbjct: 6 DLRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFY 65 Query: 44 ----NSEGETEAKKLGGNCIF---------------APANVTSEK--------EVQAALT 76 +S+ EA + + +F P V+S K + Sbjct: 66 AQEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAE 125 Query: 77 LAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVM 136 + G+ID+ V+ ++A K + + + ++ + ++++ +M Sbjct: 126 AVRADVGQIDILVH----SLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLM 181 Query: 137 GQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAP-IGIRVVT 195 + GG + AS G G S++K + +A + +RV Sbjct: 182 KE-----GGSALALSYIASEKVIPGYGGGM--SSAKAALESDCRTLAFEAGRARAVRVNC 234 Query: 196 IAPGLFATPLLTTLPDKVRNFL--------ASQVPFPSRLGDPAEYAHLVQMVIE--NPF 245 I+ G + + + + P L + + ++ Sbjct: 235 ISAGPLKSRAASAIGKAGDKTFIDLAIDYSEANAPLQKEL-ESDDVGRAALFLLSPLARA 293 Query: 246 LNGEVIRLDGAIR 258 + G + +D + Sbjct: 294 VTGATLYVDNGLH 306 >3F4B-A nrPDB Length = 323 Score = 68.0 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 40/308 (12%), Positives = 93/308 (30%), Gaps = 78/308 (25%) Query: 17 GGASGLGLSTAKRLVGQGATAV------------------------LLDVPNSEGETEAK 52 G ++G G AK L + + +++ NS+ Sbjct: 16 GDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKRMQILD 75 Query: 53 KLGGNCIFAPANVTSEK-------------EVQAALTLAKEKFGRIDVAVNCAGIAVAIK 99 L + F + E ++ L K+G+I + V+ ++A Sbjct: 76 VLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVH----SLANG 131 Query: 100 TYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAF 159 +K + + + I+ + ++ + M G +++ A+ Sbjct: 132 REVQKSLLDTSRDGYLDAISKSSYSLISLCKHFCKFMN--------SGGSVVSLTYQASQ 183 Query: 160 EGQVGQAA-YSASKGGIVGMTLPIARDLAP-IGIRVVTIAPGLFATPLLTTLP------- 210 + G S++K + T +A L IR+ TI+ G + T + Sbjct: 184 KVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQK 243 Query: 211 -----------------DKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE--NPFLNGEVI 251 D ++ P +L + + ++ + + G+ I Sbjct: 244 NNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLS-TDVGSVASFLLSKESSAVTGQTI 302 Query: 252 RLDGAIRM 259 +D + + Sbjct: 303 YVDNGLNI 310 >3SLK-A nrPDB Length = 795 Score = 61.1 bits (147), Expect = 5e-10, Method: Composition-based stats. Identities = 35/198 (17%), Positives = 70/198 (35%), Gaps = 38/198 (19%) Query: 12 VAVITGGASGLGLSTAKRLV-GQGA-TAVLLDVP------NSEGETEAKKLGGNCIFAPA 63 ++TGG LG A+ LV +G VL+ +E + G Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + + L ++ + V+ AG+ + ++ T+E +V+ + Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGV------LDDGVSESLTVERLDQVLRPKVD 644 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM----- 178 G N++ L+ + ++ +SV+ G GQ Y+A+ + + Sbjct: 645 GARNLLELIDPDVA------------LVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQ 692 Query: 179 -----TLPIARD-LAPIG 190 T +A A G Sbjct: 693 SRGLPTRSLAWGPWAEHG 710 >4LIS-A nrPDB Length = 371 Score = 56.4 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 31/183 (16%), Positives = 56/183 (30%), Gaps = 43/183 (23%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAPANVTSE 68 ++TGG +G T L+ G V+ D + ++ G FA +VT E Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 AA E ID ++ A + ++ + + +VN+ GT Sbjct: 66 ----AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDY----------YHVNVYGTI-- 109 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVA---------------AFEGQVGQAAYSASKG 173 + M ++ I+ ++S Y +K Sbjct: 110 --CLLRSMVRHNVT------NIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKF 161 Query: 174 GIV 176 I Sbjct: 162 AIE 164 >3ORF-A nrPDB Length = 251 Score = 54.5 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 37/209 (17%), Positives = 70/209 (33%), Gaps = 24/209 (11%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 S ++ GG+ LG K + + +D ++ + Sbjct: 19 SHMSKNILVLGGSGALGAEVVKFFKSKSWNTISIDF---------RENPNADHSFTIKDS 69 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E+E+++ + K ++D V AG + L+ + +I++NL F Sbjct: 70 GEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSD-----EFLKSVKGMIDMNLYSAF 124 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 + A ++ Q G+ + T + AA G AY A+K + +A + Sbjct: 125 ASAHIGAKLLNQ--------GGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASEN 176 Query: 187 A--PIGIRVVTIAPGLFATPLLTTLPDKV 213 P G + I P TP Sbjct: 177 GGLPAGSTSLGILPVTLDTPTNRKYMSDA 205 >1DIR-A nrPDB Length = 241 Score = 53.0 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 36/269 (13%), Positives = 82/269 (30%), Gaps = 52/269 (19%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 + ++ GG LG + + +DV +E + + + Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASA-------SVIVKMTDSFT 58 Query: 69 KEVQAALTLAKEKFG--RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 ++ + G ++D + AG + + L +++ I + I + Sbjct: 59 EQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLM-WKQSIWTSTISSH 117 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA--R 184 + + G++ + AA +G G Y +KG + + +A Sbjct: 118 LATK------------HLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKN 165 Query: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIE-- 242 P G + + P TP+ + +S P ++E Sbjct: 166 SGMPSGAAAIAVLPVTLDTPMNRKSMPE--ADFSSWTPLE--------------FLVETF 209 Query: 243 NPFLNG----------EVIRLDGAIRMQP 261 + ++ G +V+ DG + P Sbjct: 210 HDWITGNKRPNSGSLIQVVTTDGKTELTP 238 >2O2Y-A nrPDB Length = 349 Score = 50.7 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 30/238 (12%), Positives = 76/238 (31%), Gaps = 62/238 (26%) Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 ++ L +K+G+I++ V+ ++A +K + + + ++ + ++ + Sbjct: 112 IEDVANLIHQKYGKINMLVH----SLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCK 167 Query: 131 LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA-YSASKGGIVGMTLPIARDLAP- 188 +M II+ A+ + G S++K + T +A L Sbjct: 168 YFVNIMKPQS--------SIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRN 219 Query: 189 IGIRVVTIAPGLFATP------------------------------LLTTLPDKVRNFLA 218 IR+ TI+ G + + + + + A Sbjct: 220 YNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSA 279 Query: 219 SQ---------------VPFPSRLGDPAEYAHLVQMVIE--NPFLNGEVIRLDGAIRM 259 SQ P +L + + ++ + + G+ I +D + + Sbjct: 280 SQNYTFIDYAIEYSEKYAPLRQKLLS-TDIGSVASFLLSRESRAITGQTIYVDNGLNI 336 >1OOE-A nrPDB Length = 236 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 65/205 (31%), Gaps = 25/205 (12%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEK 69 G V ++ GG LG + + G T + +D+ A + I N + Sbjct: 4 GKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLS-------ANDQADSNILVDGNKNWTE 55 Query: 70 EVQAALTLAKEKFGR--IDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 + Q+ L +D AG + +DF + ++ + + Sbjct: 56 QEQSILEQTASSLQGSQVDGVFCVAGGWAGGS---------ASSKDFVKNADLMIKQSVW 106 Query: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD-- 185 + A + G++ T + AA Y +K + +T +A Sbjct: 107 SSAIAAKL----ATTHLKPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDS 162 Query: 186 LAPIGIRVVTIAPGLFATPLLTTLP 210 P V+TI P TP+ Sbjct: 163 GLPDNSAVLTIMPVTLDTPMNRKWM 187 >1UDA-A nrPDB Length = 338 Score = 47.6 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 62/166 (37%), Gaps = 21/166 (12%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLD-VPNSEGETE--AKKLGGNC-IFAPANVTSE 68 ++TGG+ +G T +L+ G ++LD + NS+ ++LGG F ++ +E Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNE 62 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 A +T ID ++ AG+ ++ + + N+ GT + Sbjct: 63 ----ALMTEILHDHA-IDTVIHFAGLKAVGESVQKPL----------EYYDNNVNGTLRL 107 Query: 129 IRL--VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASK 172 I A V G V +F Q+ Y SK Sbjct: 108 ISAMRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSK 153 >6BWL-A nrPDB Length = 328 Score = 47.6 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 42/269 (15%), Positives = 75/269 (27%), Gaps = 49/269 (18%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNC---IFAPANVTSEKE 70 ++TGGA +G KRL+ +LD + + + ++ +K Sbjct: 4 LVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDKKL 63 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 V N + N +++D + + IGTFN++ Sbjct: 64 VAQLFE-------------NNS--FDLCYHLAASINVQDSIDDARATFENDTIGTFNLLE 108 Query: 131 LVAGV---MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP--IARD 185 M + N ++ + + Y+ SK M L A Sbjct: 109 QCLNYDVKMVFMSTCMVYDKAT--NIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYK 166 Query: 186 LAPIGIR-VVTIAPGLFATPLLTTLPDKVRNFLASQVPF--------PSRLGDPAEYAHL 236 L + IR T P T + N VP L + A Sbjct: 167 LPVVVIRPFNTYGP-FQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCAD- 224 Query: 237 VQMVIENPFL-----------NGEVIRLD 254 V+ + G+ I ++ Sbjct: 225 --FVVAAGYSAKANGHIINAGTGQDISIN 251 >3ENK-A nrPDB Length = 341 Score = 46.4 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLD----VPNSEGETEAKKLGGNCIFAPANVTSEK 69 ++TGGA +G TA L+ G V+ D K G F +V+ E+ Sbjct: 9 LVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDER 68 Query: 70 EVQAALTL 77 + Sbjct: 69 ALARIFDA 76 >4R1T-A nrPDB Length = 337 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 20/139 (14%), Positives = 40/139 (28%), Gaps = 11/139 (7%) Query: 2 AAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGN 57 + +RSV G V +TG + K L+ +G T + + E + Sbjct: 2 SHGMRSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKER 61 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 A++ + ++ A+ D + A + + T Sbjct: 62 LTLCKADLLDYQSLREAIN-------GCDGVFHTASPVTDDPEQMVEPAVIGTKNVINAA 114 Query: 118 INVNLIGTFNVIRLVAGVM 136 N+ + A M Sbjct: 115 AEANVRRVVFTSSIGAVYM 133 >3RFT-A nrPDB Length = 267 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 28/182 (15%), Positives = 49/182 (26%), Gaps = 49/182 (26%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 ++TG A LG +RL L D+ + G N ++ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSPLDPA------GPNEECVQCDLADANA 57 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIR 130 V A + D V+ GI+V F++++ N+IG +N+ Sbjct: 58 VNAMVA-------GCDGIVHLGGISVEKP--------------FEQILQGNIIGLYNLYE 96 Query: 131 LVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQ------------AAYSASKGGIVGM 178 + I+ +S Y SK + Sbjct: 97 AARAH----------GQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENL 146 Query: 179 TL 180 Sbjct: 147 AR 148 >1Z45-A nrPDB Length = 699 Score = 43.3 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 42/99 (42%), Gaps = 10/99 (10%) Query: 1 MAAAVRS-VKGLVAVITGGASGLGLSTAKRLVGQGAT-AVLLDVPNSEGETEAK---KLG 55 M A ++S + ++TGGA +G T L+ G V ++ NS ++ A+ Sbjct: 1 MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTK 60 Query: 56 GNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGI 94 + F ++ K ++ +ID ++ AG+ Sbjct: 61 HHIPFYEVDLCDRKGLEKVFKEY-----KIDSVIHFAGL 94 >2PK3-A nrPDB Length = 321 Score = 43.3 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 35/230 (15%), Positives = 64/230 (27%), Gaps = 48/230 (20%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 A+ITG A +G A L Q N KL N ++ + V+ Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFGTSRNNE------AKLP-NVEMISLDIMDSQRVK 67 Query: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 ++ + D + A + ++ KK + N+ GT + V Sbjct: 68 KVISDI-----KPDYIFHLAAKSSVKDSWLNKKG----------TFSTNVFGTLH----V 108 Query: 133 AGVMGQNEPDQGGQRGVIINTAS-------------VAAFEGQVGQAAYSASKGGIVGMT 179 + + D I+ S V+ + Y SK + + Sbjct: 109 LDAVRDSNLDC-----RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLA 163 Query: 180 LPIARDLAPIGI---RVVTIAPGLFATPLLTTLPDKVRN-FLASQVPFPS 225 + I I PG + ++ + + Q P Sbjct: 164 RQYVKAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIK 213 >5N2I-A nrPDB Length = 232 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 25/83 (30%) Query: 2 AAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA 61 + V GL + GG G A+R G +L + A +LG Sbjct: 11 PHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVR 70 Query: 62 PANVTSEKEVQAALTLAKEKFGR 84 + E + +A G Sbjct: 71 GMDNAGAAEAGDVVIVAVPWDGH 93 >6ACF-A nrPDB Length = 367 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 55/174 (31%), Gaps = 17/174 (9%) Query: 7 SVKGLVAVITGGASGLG---LSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI---- 59 S++G V + G+G + L +GA ++ D+ ++ G + Sbjct: 170 SLEGKVVAV----QGVGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPND 225 Query: 60 --FAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 ++ + + + + V A + + + +++ + V Sbjct: 226 IYGVECDIFAPCALGGIINDQTIPQLKAKVIAGSANNQLKEPRHGDMIHEMGIVYAPDYV 285 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS 171 I N G NV + G + + Q N V A + Y A+ Sbjct: 286 I--NAGGVINVADELYGYNRERAMKKIEQIYD--NIEKVFAIAKRDNIPTYVAA 335 >2Z95-A nrPDB Length = 345 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 45/270 (16%), Positives = 89/270 (32%), Gaps = 41/270 (15%) Query: 8 VKGLVAVITGGASGL-GLSTAKRLVGQGATAVLLDVPNSE-GETEAKKLG--GNCIFAPA 63 + G A+ITG G G AK L+ +G D + E K+LG + Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHM 59 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 ++ + + + D N A + ++ + + T E V+ I Sbjct: 60 DLLEFSNIIRTIEKV-----QPDEVYNLAAQSFVGVSFEQ---PILTAE-------VDAI 104 Query: 124 GTFNV---IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179 G + +R V + G + ++ Y+ +K +T Sbjct: 105 GVLRILEALRTVKPDTKFYQASTSEMFGKVQEIP-QTEKTPFYPRSPYAVAKLFGHWITV 163 Query: 180 --LPIARDLAPIGIRVVTIAP--GL-FATPLLTTLPDKVRNFLASQVPF----PSR-LGD 229 A GI +P G+ F T +T +++ L ++ R G Sbjct: 164 NYREAYNMFACSGILFNHESPLRGIEFVTRKITYSLARIKYGLQDKLVLGNLNAKRDWGY 223 Query: 230 PAEYAHLVQMVIE----NPFL--NGEVIRL 253 EY + ++++ + ++ GE + Sbjct: 224 APEYVEAMWLMMQQPEPDDYVIATGETHTV 253 >2P4H-X nrPDB Length = 322 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 34/91 (37%), Gaps = 10/91 (10%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG------NCIFAP 62 KG V +TGG LG K L+ G + + E + + L F Sbjct: 1 KGRVC-VTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFN 59 Query: 63 ANVTSEKEVQAALTLAKEKF---GRIDVAVN 90 A++++ AA+ F ID AV+ Sbjct: 60 ADLSNPDSFAAAIEGCVGIFHTASPIDFAVS 90 >1I3M-A nrPDB Length = 348 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 33/198 (16%), Positives = 60/198 (30%), Gaps = 57/198 (28%) Query: 13 AVITGGASGLGLSTAKRLVGQGAT-AVLLDVPNS--------EGETEAKKL-GGNCIFAP 62 ++TGGA +G T L+ G V+ + N+ E ++L G + F Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64 Query: 63 ANVTSEKEVQAALTL----AKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 ++ + +Q A F AG+ ++ + + Sbjct: 65 MDILDQGALQRLFKKYSFMAVIHF---------AGLKAMGESVQKPLDY----------Y 105 Query: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQA------------ 166 VNL GT + +M + ++ ++S A G Sbjct: 106 RVNLTGTIQL----LEIMKAHGVK------NLVFSSS-ATVYGNPQYLPLDEAHPTGGCT 154 Query: 167 -AYSASKGGIVGMTLPIA 183 Y SK I M + Sbjct: 155 NPYGKSKFFIEEMIRDLC 172 >1VL0-A nrPDB Length = 292 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 52/180 (28%), Gaps = 55/180 (30%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 +ITG LG K+L G+ + DV + ++T+ V Sbjct: 16 LITGANGQLGREIQKQLKGKNVEVIPTDVQD------------------LDITNVLAVNK 57 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVA 133 + +V +NCA K E + +N IG N+ Sbjct: 58 FFNE-----KKPNVVINCAAHTAVDKC----------EEQYDLAYKINAIGPKNLAAAAY 102 Query: 134 GVMGQNEPDQGGQRGVIINTASVAAFEGQV-----------GQAAYSASKGGIVGMTLPI 182 V I+ ++ F+G+ Q+AY +K + Sbjct: 103 SV-----------GAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >4PVC-A nrPDB Length = 342 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 12/124 (9%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 ++G + L+ + + + E + G N F+ V ++ Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 73 AALTLAKEKFGR-IDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN-LIGTFNVIR 130 A +K G+ I + ++ A T E+ + VN + G + I+ Sbjct: 63 -AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIP---------AVNGVKGILHSIK 112 Query: 131 LVAG 134 A Sbjct: 113 KYAA 116 >5K1S-A nrPDB Length = 362 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 8/97 (8%) Query: 9 KGLVAVITGGASGLGLSTAKRLVG-QGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 G +ITG + G+GLS + +L GA + + ++ + K+ G + + + Sbjct: 183 AGETVLITGASGGVGLS-SVQLARLDGARVIAVTSSEAKVQAL-KEAGADEVIVSRGLDF 240 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEK 104 +V+ A +DVAV G A +T Sbjct: 241 ASDVRKRTQGA-----GVDVAVEIVGSATFDQTLKSM 272 >1R66-A nrPDB Length = 337 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 40/258 (15%), Positives = 76/258 (29%), Gaps = 42/258 (16%) Query: 14 VITGGASGLGLSTAKRLVGQGAT-------AVLLD---VPNSEGETEAKKLGGNCIFAPA 63 ++TGGA +G ++L+ GA ++LD + F Sbjct: 4 LVTGGAGFIGSHFVRQLLA-GAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHG 62 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 ++ L + +D V+ A + ++ N+ Sbjct: 63 DIRDAG-------LLARELRGVDAIVHFAAESHVDRSIAGASVFT----------ETNVQ 105 Query: 124 GTFNVIRLV--AGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 GT +++ AGV G I ++ S + Y+ASK G + Sbjct: 106 GTQTLLQCAVDAGVGRVVHVSTDEVYGSI-DSGSWTESSPLEPNSPYAASKAGSDLVARA 164 Query: 182 IARDLAPI-GIR--VVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQ 238 R I P P+K+ + + L + A++ + Sbjct: 165 YHRTYGLDVRITRCCNNYGP--------YQHPEKLIPLFVTNLLDGGTLPLYGDGANVRE 216 Query: 239 MVIENPFLNGEVIRLDGA 256 V + G + L G Sbjct: 217 WVHTDDHCRGIALVLAGG 234 >3VPX-A nrPDB Length = 364 Score = 38.7 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 25/70 (35%), Gaps = 7/70 (10%) Query: 7 SVKGLVAVITGGASGLG---LSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 S+ G + G+G + + L +GA ++ D+ + G + Sbjct: 170 SLAGKTVAV----QGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINE 225 Query: 64 NVTSEKEVQA 73 + E ++ A Sbjct: 226 IYSQEADIFA 235 >2GN9-A nrPDB Length = 344 Score = 38.7 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 46/137 (33%), Gaps = 20/137 (14%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKR-LVGQGATAVLLDVPNSEGETEAKKLGG--N 57 M + +ITGG G ++ L A +++ + ++E Sbjct: 12 MPNHQNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPR 71 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 F +V + + AL +D+ ++ A + H + + LE Sbjct: 72 MRFFIGDVRDLERLNYALE-------GVDICIHAAALK------HVPIAEYNPLE----C 114 Query: 118 INVNLIGTFNVIRLVAG 134 I N++G NVI Sbjct: 115 IKTNIMGASNVINACLK 131 >6DEB-A nrPDB Length = 285 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 26/63 (41%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 + A ++G AVI G ++ +G A L+ GAT + + + ++ + Sbjct: 151 LKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQADLIIVA 210 Query: 61 APA 63 A Sbjct: 211 AGC 213 >4J6F-A nrPDB Length = 382 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 27/74 (36%), Gaps = 2/74 (2%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 M R G ++TG + G+G + + +GA + + P E Sbjct: 198 MLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTR 257 Query: 61 APANVTSEKEVQAA 74 ++ + V+AA Sbjct: 258 GQGDLA--EAVEAA 269 >2HUN-A nrPDB Length = 336 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 28/180 (15%), Positives = 64/180 (35%), Gaps = 30/180 (16%) Query: 14 VITGGASGLGLSTAKRLVGQ--GATAVLLD---VPNSEGETEAKKLGGNCIFAPANVTSE 68 ++TGG +G + + ++ + + +D ++ + + F +V Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVKGDVADY 66 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 + V+ + ++D V+ A + + E F ++ N+IGT+ + Sbjct: 67 ELVKELVR-------KVDGVVHLAA-------ESHVDRSISSPEIF---LHSNVIGTYTL 109 Query: 129 ---IRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG----IVGMTLP 181 IR + G I+ S + + + YSA+K ++G T Sbjct: 110 LESIRRENPEVRFVHVSTDEVYGDILK-GSFTENDRLMPSSPYSATKAASDMLVLGWTRT 168 >1LU9-A nrPDB Length = 287 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAP 62 AA SVKG AV+ G +G+ +A L G+GA VL + + A + Sbjct: 112 AAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKR---FK 168 Query: 63 ANVTSEKEVQAA 74 NVT+ + A Sbjct: 169 VNVTAAETADDA 180 >5INT-A nrPDB Length = 220 Score = 38.3 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 47/133 (35%), Gaps = 33/133 (24%) Query: 6 RSVKGLVAVITGG---------------ASG-LGLSTAKRLVGQGATAVLLDVPNSEGET 49 +++G +IT G +SG +G + A+ V GA +L+ Sbjct: 2 NALQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS-------- 53 Query: 50 EAKKLGGNCIFAPANVT--SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQ 107 G + P +VT + Q L + + +DV + A +A Y + Sbjct: 54 -----GPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVADYRPKYVH--DN 106 Query: 108 VHTLEDFQRVINV 120 ++ VI + Sbjct: 107 KMKKKNGDAVIEL 119 >1BXK-A nrPDB Length = 355 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 28/188 (14%), Positives = 57/188 (30%), Gaps = 31/188 (16%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGAT-AVLLDVPNSEGETEAKKL---GGNCIFAPANVT 66 +ITGGA +G + + ++ + + V++D G + F ++ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 E+ T + D ++ A + ++ I N++GT+ Sbjct: 62 DRAELARVFTEH-----QPDCVMHLAAESHVDRSIDGPAAF----------IETNIVGTY 106 Query: 127 NVIRLVAGVMGQNEPDQGGQ-RGVIINTASVAA-----------FEGQVGQAAYSASKGG 174 ++ D+ R I+T V + YSASK Sbjct: 107 TLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKAS 166 Query: 175 IVGMTLPI 182 + Sbjct: 167 SDHLVRAW 174 >2Q1W-A nrPDB Length = 333 Score = 37.6 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 38/123 (30%), Gaps = 21/123 (17%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 ITG +G A+ L+ +G V +D + K N F ++ Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHP-NLTFVEGSIADHAL 80 Query: 71 VQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDF-QRVINVNLIGTFNVI 129 V + + D V+ A +D+ + N +G NV+ Sbjct: 81 VNQLIGDL-----QPDAVVHTAA-------------SYKDPDDWYNDTL-TNCVGGSNVV 121 Query: 130 RLV 132 + Sbjct: 122 QAA 124 >4G5H-A nrPDB Length = 363 Score = 37.2 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 27/188 (14%), Positives = 56/188 (29%), Gaps = 29/188 (15%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNC--IFAPANV 65 + +ITGG G + KR + + + + + + + +K N F +V Sbjct: 23 FDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYIGDV 82 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVA-----IKTYHEKKNQVHTLEDFQRVINV 120 + V+ A+ +D + A + K N + T Q I+ Sbjct: 83 RDSQSVETAMRD-------VDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIHQ 135 Query: 121 NLIGTFNVI--RLVAG--------VMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSA 170 N+ + + M + + N S A Sbjct: 136 NVKKVICLSTDKAAYPINAMGISKAMMEKVFVAKSR-----NIRSEQTLICGTRYGNVMA 190 Query: 171 SKGGIVGM 178 S+G ++ + Sbjct: 191 SRGSVIPL 198 >4A10-A nrPDB Length = 447 Score = 36.8 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 +G + +I G + GLG S A + V G + V +++ E + LG + + A + Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 69 KEVQAALTLAKEKFGRI-DVAVNCAGIAVAIKTYHEKK 105 ++ E ++ + V AG I H + Sbjct: 279 DDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGR 316 >1WVG-A nrPDB Length = 359 Score = 36.4 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 29/179 (16%), Positives = 58/179 (32%), Gaps = 38/179 (21%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATA--VLLDVPNSEGETEAKKLGGNCIFAPANVT 66 +G +TG G + L GA LD P E +L ++ Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHIGDIR 67 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 +++++++ + ++ + A + + E + + N++GT Sbjct: 68 DFEKLRSSIAEF-----KPEIVFHMAA----------QPLVRLSYEQPIKTYSTNVMGTV 112 Query: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTAS---------VAAFE---GQVGQAAYSASKG 173 +++ V Q G ++N S V + G YS SKG Sbjct: 113 HLLETV---------KQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >1ZDL-A nrPDB Length = 517 Score = 36.4 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 ++ GG SG GL+ AK G + D LGG C+ Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGC 84 >4EUF-A nrPDB Length = 418 Score = 36.0 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 33/96 (34%), Gaps = 17/96 (17%) Query: 11 LVAVITGGASGLGLS--TAKRLVGQGATAVLLDVPNSEGE---------------TEAKK 53 +I G +SG GL+ + G A + + + AKK Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 54 LGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAV 89 G + S + + K++FG+ID+ V Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >2C20-A nrPDB Length = 330 Score = 36.0 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 +I GGA +G K+LV +G + V++D G +A G F ++ + ++ Sbjct: 5 LICGGAGYIGSHAVKKLVDEGLSVVVVD-NLQTGHEDAITEGAK--FYNGDLRDKAFLRD 61 Query: 74 ALTL 77 T Sbjct: 62 VFTQ 65 >4K28-A nrPDB Length = 269 Score = 36.0 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 20/49 (40%), Gaps = 2/49 (4%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQG-ATAVLLDVPNSEGETEAKKLGG 56 G A++ G G+G + A L G A+ L D + + LG Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGN 171 >4EJ6-A nrPDB Length = 370 Score = 35.6 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 VA++ GG +GL T + GAT V+L + A+++G + ++ V Sbjct: 186 VAILGGGV--IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATA---TVDPSAGDVV 240 Query: 72 QAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL 111 +A G +DV + CAG+A +K T+ Sbjct: 241 EAIAGPVGLVPGGVDVVIECAGVAETVKQSTRLAKAGGTV 280 >5F5N-A nrPDB Length = 289 Score = 35.6 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 25/72 (34%), Gaps = 1/72 (1%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKE 70 ++TG G +T + L+ +G L V + + ++ + Sbjct: 2 RTILVTGATGTQGGATVRALLARGRPVRAL-VRDPGTDAARALAAAGVSLVTGDLNDQAS 60 Query: 71 VQAALTLAKEKF 82 ++AA+ F Sbjct: 61 LRAAMADVHGVF 72 >1U3W-A nrPDB Length = 374 Score = 35.2 bits (80), Expect = 0.025, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 50/155 (32%), Gaps = 26/155 (16%) Query: 11 LVAVITGGA-------SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 VA +T G+ G+GLS GA ++ N + +AK+LG P Sbjct: 185 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 244 Query: 64 NVTSE------KEVQAALTLAKEKFGRIDVAVNC-------------AGIAVAIKTYHEK 104 + + + + E G++D + G+ + Sbjct: 245 DYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNLSIN 304 Query: 105 KNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQN 139 + T ++ I +V +LVA M + Sbjct: 305 PMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKK 339 >3IP1-A nrPDB Length = 404 Score = 35.2 bits (80), Expect = 0.025, Method: Composition-based stats. Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEK 69 G VI GG +GL+ L GA+ V+L P+ AK+LG + + + T E Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVI---DPTKEN 269 Query: 70 EVQAALT 76 V+A L Sbjct: 270 FVEAVLD 276 >1JPH-A nrPDB Length = 388 Score = 35.2 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 29/82 (35%), Gaps = 9/82 (10%) Query: 28 KRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANV------TSEKEVQAALTLAKEK 81 + L G V LD + + A++ G + N+ SE+E+ + + Sbjct: 291 EELAQAGYEVVGLDWTVAPKK--ARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDD 348 Query: 82 FGRIDVAVN-CAGIAVAIKTYH 102 FG N G+ + H Sbjct: 349 FGPHRYIANLGHGLYPDMDPEH 370 >6G2J-P nrPDB Length = 377 Score = 35.2 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 56/167 (33%), Gaps = 21/167 (12%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG--GNCIFAPA 63 SV G+VA + G LG L G+ ++ + + +G G F Sbjct: 49 SSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQLTFLEW 108 Query: 64 NVTSEKEVQAALTL---AKEKFGR---------IDVAVNCAGIAVAIKTYHEKKNQVHTL 111 + + ++ A+ GR DV VN I + ++ + Sbjct: 109 DARDKDSIRKAVQHSNVVINLIGREWETRNFDFEDVFVN-------IPRAIAQASKEAGV 161 Query: 112 EDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAA 158 E F V ++N + L + +G+ E +II + + Sbjct: 162 ERFIHVSHLNASMKSSSKSLRSKAVGEKEVRSVFPEAIIIRPSDIFG 208 >5YWN-A nrPDB Length = 334 Score = 35.2 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 44/147 (29%), Gaps = 22/147 (14%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 ++G L ++ +G V +G K G + V E + Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDD---FSYEVVKVLEQK 61 Query: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 A A +K + + H +ED ++ I LI N + V Sbjct: 62 GAFDEALKKHPEVTIF------------LHTASPVTFEVEDTEKEI---LIPAINGTKYV 106 Query: 133 AGVMGQNEPDQGGQRGVIINTASVAAF 159 + P ++ T+SV A Sbjct: 107 LQSIKDVAPQIT----RVVYTSSVVAM 129 >6GCS-E nrPDB Length = 375 Score = 35.2 bits (80), Expect = 0.030, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 29/84 (34%), Gaps = 10/84 (11%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG--GNCIFAPANVT 66 G A + G LG +L G T V+ + K G G F ++ Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYR-EEMAKRHLKVTGDLGVVNFLEMDLR 110 Query: 67 SEKEVQAALTLAKEKFGRIDVAVN 90 + + + A+ + D+ VN Sbjct: 111 NLESIDEAVRHS-------DIVVN 127 >3OND-A nrPDB Length = 488 Score = 35.2 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 M A + G VAV+ G +G A L GA ++ ++ + +A G + Sbjct: 256 MRATDVMIAGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEI-DPICALQATMEGLQVLT 313 Query: 61 APANVTSEKEV 71 +V SE ++ Sbjct: 314 LE-DVVSEADI 323 >5ENV-A nrPDB Length = 347 Score = 35.2 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 8/91 (8%) Query: 15 ITGGASGLGLSTAKRLVGQ-GATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 I+G A GLG S A + G + +D E + +GG + T EK++ Sbjct: 175 ISGAAGGLG-SLAVQYAKAMGYRVLGID-GGEGKEELFRSIGGEVFI---DFTKEKDIVG 229 Query: 74 ALTLAKE--KFGRIDVAVNCAGIAVAIKTYH 102 A+ A + G I+V+V+ A I + + Sbjct: 230 AVLKATDGGAHGVINVSVSEAAIEASTRYVR 260 >6ACQ-A nrPDB Length = 302 Score = 34.9 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 17/39 (43%), Gaps = 2/39 (5%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS 45 S V VI GA +G A+ +G VL D+ + Sbjct: 19 SHMKKVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDE 55 >2V3C-C nrPDB Length = 432 Score = 34.9 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 30/138 (21%), Positives = 54/138 (39%), Gaps = 6/138 (4%) Query: 38 VLLDVPNSEGETEAKKLGGNC-IFAPANVTSEKEVQAALTLAKEKFGRIDVAV-NCAGIA 95 + D + K+L + + T K + EKF + DV + + AG Sbjct: 133 IAADTYRPAAYEQLKQLAEKIHVPIYGDETRTKSPVDIVKEGMEKFKKADVLIIDTAGRH 192 Query: 96 VAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTAS 155 K E+ Q+ + + +I V + GT I AG+ + + G+ G II T Sbjct: 193 KEEKGLLEEMKQIKEITNPDEIILV-IDGT---IGQQAGIQAKAFKEAVGEIGSIIVTKL 248 Query: 156 VAAFEGQVGQAAYSASKG 173 + +G +A + +K Sbjct: 249 DGSAKGGGALSAVAETKA 266 >2EXX-A nrPDB Length = 306 Score = 34.9 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 28/76 (36%), Gaps = 2/76 (2%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQG-ATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 V + V+ GG G S A+ L+ G ++ + + +L G + Sbjct: 9 VDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQG-AEVVQGDQD 67 Query: 67 SEKEVQAALTLAKEKF 82 + ++ AL A F Sbjct: 68 DQVIMELALNGAYATF 83 >1GY8-A nrPDB Length = 397 Score = 34.9 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 34/180 (18%), Positives = 64/180 (35%), Gaps = 48/180 (26%) Query: 13 AVITGGASGLGLSTAKRLVGQ-GATAVLLDV---------PNSEGETEAKKLGGN----- 57 ++ GGA +G + L+ + V++D E A+KL + Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 58 ------CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVN-CAGIAVAIKTYHEKKNQVHT 110 +V +E L + G ID V+ CA +AV + Sbjct: 65 PWADRYAALEVGDVRNED----FLNGVFTRHGPIDAVVHMCAFLAVG-----------ES 109 Query: 111 LEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSA 170 + D + + N++G +++ M ++ D+ II ++S AA G + S Sbjct: 110 VRDPLKYYDNNVVGILRLLQA----MLLHKCDK------IIFSSS-AAIFGNPTMGSVST 158 >1O89-A nrPDB Length = 345 Score = 34.9 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSE 46 A VR G + V+TG + G+G + L G V + S Sbjct: 162 AGVRPQDGEI-VVTGASGGVGSTAVALLHKLGYQVVAVSGREST 204 >2VN8-A nrPDB Length = 375 Score = 34.5 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 32/91 (35%), Gaps = 10/91 (10%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANV 65 ++ G +I G + G+G + + A + + + +KLG + +V Sbjct: 180 KNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVC--SQDASELVRKLGAD------DV 231 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAV 96 K ++ + D ++ G + Sbjct: 232 IDYKS--GSVEEQLKSLKPFDFILDNVGGST 260 >2NNL-D nrPDB Length = 337 Score = 34.5 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 25/79 (31%), Gaps = 5/79 (6%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATA--VLLDVPNSEGETEAKKLGGNCIFA---PA 63 + +TG + +G RL+ +G T + D N + L A Sbjct: 4 QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKA 63 Query: 64 NVTSEKEVQAALTLAKEKF 82 ++ E A+ F Sbjct: 64 DLADEGSFDEAIKGCTGVF 82 >1KEU-A nrPDB Length = 361 Score = 34.5 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 29/206 (14%), Positives = 54/206 (26%), Gaps = 39/206 (18%) Query: 14 VITGGASGLGLSTAKRLVGQ-GATAVLLDVPNSEGETEAKK---LGGNCIFAPANVTSEK 69 +ITGGA +G + + ++ T V +D G E+ F A++ Sbjct: 4 LITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDSA 63 Query: 70 EVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 E+ + D ++ A + F I N++GT+ ++ Sbjct: 64 EITRIFEQY-----QPDAVMHLAA-------ESHVDRSITGPAAF---IETNIVGTYALL 108 Query: 130 RLVAGVMGQNEPDQGGQRG--------------------VIINTASVAAFEGQVGQAAYS 169 + D+ + + YS Sbjct: 109 EVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYS 168 Query: 170 ASKGGIVGMTLPIARDLAPIGIRVVT 195 ASK + R I Sbjct: 169 ASKASSDHLVRAWRRTYGLPTIVTNC 194 >2Q4B-A nrPDB Length = 253 Score = 34.5 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 25/78 (32%), Gaps = 9/78 (11%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 ++TG + G K+L V + S E K+GG ++T + Sbjct: 6 TVLVTGASGRTGQIVYKKLKEGSDKFVAKGLVRSAQGKE--KIGGEADVFIGDITDADSI 63 Query: 72 QAALTLAKEKFGRIDVAV 89 A ID V Sbjct: 64 NPAFQ-------GIDALV 74 >4J2O-A nrPDB Length = 363 Score = 34.5 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 43/129 (33%), Gaps = 19/129 (14%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKK--LGGNCIFAPANV 65 K V +ITGG G + KR + + + + + + + +K F +V Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYIGDV 80 Query: 66 TSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGT 125 + A +D + A + + H +E + N++GT Sbjct: 81 RDYNSILNATR-------GVDYIYHAAALKQVP------SCEFHPMEAVK----TNVLGT 123 Query: 126 FNVIRLVAG 134 NV+ Sbjct: 124 ENVLEAAIQ 132 >2PZM-A nrPDB Length = 330 Score = 34.5 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 53/171 (30%), Gaps = 30/171 (17%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 +ITGGA LG + + + QG +++D + G+ E +VT ++ Sbjct: 24 LITGGAGCLGSNLIEHWLPQGHEILVID-NFATGKREVLPPVAGLSVIEGSVTDAGLLER 82 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVA 133 A K V+ A +D+ N+ G+ NV + + Sbjct: 83 AFDSFKPTH-----VVHSAA-------------AYKDPDDWAEDAATNVQGSINVAKAAS 124 Query: 134 -----GVMGQNEPDQGGQRGVI-INTASVAAFEGQVGQAAYSASKGGIVGM 178 ++ G+ + I S +Y SK Sbjct: 125 KAGVKRLLNFQTALCYGRPATVPIPIDS-----PTAPFTSYGISKTAGEAF 170 >2DFV-A nrPDB Length = 347 Score = 34.1 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 10/92 (10%) Query: 10 GLVAVITGGA--SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 G +ITG LG++ AK GA V++ P+ AKK+G + + P Sbjct: 167 GKSVLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSDFRRELAKKVGADYVINPF---- 219 Query: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIK 99 E++V + + G +DV + +G A++ Sbjct: 220 EEDVVKEVMDITDGNG-VDVFLEFSGAPKALE 250 >2HK7-A nrPDB Length = 269 Score = 33.7 bits (76), Expect = 0.091, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 VK ++ G G + LV +GA L + + A+K + +P V Sbjct: 121 VKEKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVID 179 Query: 68 EKEV 71 + +V Sbjct: 180 KVQV 183 >3DFZ-A nrPDB Length = 223 Score = 33.3 bits (75), Expect = 0.095, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 34/106 (32%), Gaps = 20/106 (18%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKR----LVGQGATAVLLDVPNSEGETEAKKLGG 56 M + +KG ++ GG + A R + +GA ++ P E + G Sbjct: 22 MYTVMLDLKGRSVLVVGGGT-----IATRRIKGFLQEGAAITVVA-PTVSAEINEWEAKG 75 Query: 57 NCIFAPANVTSEKEV----------QAALTLAKEKFGRIDVAVNCA 92 V E + A+ ++ + D VN A Sbjct: 76 QLRVKRKKVGEEDLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMA 121 >1EE2-A nrPDB Length = 373 Score = 33.3 bits (75), Expect = 0.096, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 50/155 (32%), Gaps = 26/155 (16%) Query: 11 LVAVITGGA-------SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 VA +T G+ G+GLS GA ++ N + +AK++G P Sbjct: 184 KVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQ 243 Query: 64 NVTSE------KEVQAALTLAKEKFGRIDVAVNC-------------AGIAVAIKTYHEK 104 + + + + E GR+D V G+ + Sbjct: 244 DYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMN 303 Query: 105 KNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQN 139 + + ++ I +V +LVA M + Sbjct: 304 PMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKK 338 >5GUP-L nrPDB Length = 377 Score = 33.3 bits (75), Expect = 0.097, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 38/114 (33%), Gaps = 9/114 (7%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG--GNCIFAPA 63 SV G+VA + G LG L G+ ++ + +G G IF Sbjct: 49 SSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFMEW 108 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 N + ++ + + +V +N G K + + V +V Sbjct: 109 NGKDKDSIRKVVEHS-------NVVINLVGREWETKNFDFEDVFVKIPHAIAQV 155 >5AOV-A nrPDB Length = 336 Score = 33.3 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 32/96 (33%), Gaps = 14/96 (14%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G I G +G + A+R +G +L + K+LG + Sbjct: 148 LYGKTIGIVGFGR-IGQAIARR--AKGFNMRILYYSRTRKSQAEKELGAEYRPLEEVLKE 204 Query: 68 EKEVQAALTLAKEKFGRID-----------VAVNCA 92 V A+ L KE I+ + VN A Sbjct: 205 SDFVILAVPLTKETMYMINEERLKLMKPTAILVNIA 240 >3COS-A nrPDB Length = 381 Score = 33.3 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 8/88 (9%) Query: 18 GASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTL 77 G G+GLS GA+ ++ NSE +AK LG + + +++ + Sbjct: 206 GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT------DCLNPRDLHKPIQE 259 Query: 78 AKEKF--GRIDVAVNCAGIAVAIKTYHE 103 + G +D A++CAG + +K + Sbjct: 260 VIIELTKGGVDFALDCAGGSETMKAALD 287 >4DGK-A nrPDB Length = 501 Score = 33.3 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 15 ITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG--ETEAKKLGGNCIFAPANVTSEKEVQ 72 + G G GL+ A RL G +LL+ + G + G P +T ++ Sbjct: 6 VIGAGFG-GLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAIE 64 Query: 73 AALTLAKEKF 82 LA ++ Sbjct: 65 ELFALAGKQL 74 >4UUP-A nrPDB Length = 341 Score = 32.9 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 32/106 (30%), Gaps = 19/106 (17%) Query: 13 AVITGGASGLGLSTAKRLVGQ---GATAVLLDVPN-----SEGETEAKKLGGNCIFAPAN 64 +ITG A +G + A R+ G V+L + E +L A Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 65 VTSEKEVQAALTLAKEKF-----------GRIDVAVNCAGIAVAIK 99 V + + + A F R D+ AGI Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQG 112 >2C54-A nrPDB Length = 379 Score = 32.9 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 21/68 (30%), Gaps = 3/68 (4%) Query: 15 ITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA 74 ITG + A+RL +G + D +E TE F ++ + Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKNEHMTEDMFCD---EFHLVDLRVMENCLKV 90 Query: 75 LTLAKEKF 82 F Sbjct: 91 TEGVDHVF 98 >1ZZE-A nrPDB Length = 342 Score = 32.9 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 22/161 (13%), Positives = 48/161 (29%), Gaps = 33/161 (20%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE-----AKKLGGNCIFAPA 63 +G + ++TG + ++L+ G S+ AK G Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVE 69 Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 ++ + + A AG+A + V + V+ + Sbjct: 70 DMLKQGAYDEVIKGA-------------AGVA-------HIASVVSFSNKYDEVVTPAIG 109 Query: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVG 164 GT N +R A ++ +++V+A + Sbjct: 110 GTLNALRAAAATPSVKRF--------VLTSSTVSALIPKPN 142 >2EER-A nrPDB Length = 347 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 11 LVAVITGGASGLGL-STAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 V+ G GLG + GAT + +DV E AK+ G + + Sbjct: 172 KTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEA-AKRAGADYVI 221 >4WOK-A nrPDB Length = 336 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 4/65 (6%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 ++ GGA +G TAK L GQG V+ D S G A + G F ++ + + Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVVYD-NLSTGHQSAVRWGD---FVEGDILDQARLV 69 Query: 73 AALTL 77 + Sbjct: 70 ETMEK 74 >3SXP-A nrPDB Length = 362 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 30/204 (14%), Positives = 57/204 (27%), Gaps = 32/204 (15%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQ--GATAVLLDVPNSEGETEAKK----------LG 55 ++ +ITGGA +G + A A V+LD S + +G Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 56 GNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQ 115 A++ + +++ L D + A ++ E Sbjct: 68 FKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQEL----------- 110 Query: 116 RVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGI 175 V+ N N++ + + +V Y SK + Sbjct: 111 -VMKTNYQAFLNLLEIARSKKAKVIYASSAGVYGNTKAPNVVGKNESPEN-VYGFSKLCM 168 Query: 176 VGMTLPIARDLAPIGIR-VVTIAP 198 L + D +G+R P Sbjct: 169 DEFVLSHSNDNVQVGLRYFNVYGP 192 >3NJ4-A nrPDB Length = 435 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 9/81 (11%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 G VAV+ G +G A+ L G GA ++ ++ A + VT+ Sbjct: 215 AGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAME--------GYEVTTM 265 Query: 69 KEVQAALTLAKEKFGRIDVAV 89 E + G ID+ + Sbjct: 266 DEACQEGNIFVTTTGCIDIIL 286 >4KTT-E nrPDB Length = 327 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL 54 ++TG LG + K AV + + E L Sbjct: 22 RRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNL 65 >5B6K-A nrPDB Length = 366 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 21/150 (14%), Positives = 48/150 (32%), Gaps = 24/150 (16%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL--GGNC-IFAPANVTSE 68 ++G + ++L+ Q + +G+ + GG+ +++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 A EK G+ D+ V H D ++ + LI N Sbjct: 83 ----TAFDHVFEKHGK-DIKV----------VLHTASPFHFNTTDIEKDL---LIPAVNG 124 Query: 129 IRLVAGVMGQNEPDQGGQRGVIINTASVAA 158 + + + + + ++ T+S AA Sbjct: 125 TKGILESIKKYAAQTVER---VVVTSSFAA 151 >6BII-A nrPDB Length = 333 Score = 32.2 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 33/97 (34%), Gaps = 14/97 (14%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 V G I G +G + AKR +G +L S K+LG + Sbjct: 147 DVYGKTIGIVGFGR-IGQAIAKR--AKGFGMRILYTARSRKPEAEKELGAEFKPLEELLR 203 Query: 67 SEKEVQAALTLAKEKFGRID-----------VAVNCA 92 V A+ L KE + I+ V VN A Sbjct: 204 ESDFVVLAVPLTKETYHMINEERLRLMKPTAVLVNVA 240 >6BMQ-A nrPDB Length = 523 Score = 32.2 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 6/30 (20%), Positives = 12/30 (40%) Query: 32 GQGATAVLLDVPNSEGETEAKKLGGNCIFA 61 +GA V+ + A+ +GG + Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKALSL 414 >1OC2-A nrPDB Length = 348 Score = 32.2 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 26/201 (12%), Positives = 52/201 (25%), Gaps = 33/201 (16%) Query: 11 LVAVITGGASGLGLSTAKRLVGQ--GATAVLLDVPNSEG--ETEAKKLGGNCIFAPANVT 66 ++TGGA +G + + +LD G LG ++ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 + V A D V+ A + + ++ I+ N IGT+ Sbjct: 65 DAELVDKLAAKA-------DAIVHYAAESHNDNSLNDPSPF----------IHTNFIGTY 107 Query: 127 NVIRLVAGV-MGQNEPDQGGQRGVIINTASVAAFEGQVG-----------QAAYSASKGG 174 ++ + + G + + G + YS++K Sbjct: 108 TLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAA 167 Query: 175 IVGMTLPIARDLAPIGIRVVT 195 + R Sbjct: 168 SDLIVKAWVRSFGVKATISNC 188 >1HSZ-A nrPDB Length = 374 Score = 32.2 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 50/154 (32%), Gaps = 26/154 (16%) Query: 12 VAVITGGA-------SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 VA +T G+ G+GLS GA ++ N + +AK+LG P + Sbjct: 186 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 245 Query: 65 VTSE------KEVQAALTLAKEKFGRIDVAVNC-------------AGIAVAIKTYHEKK 105 + + + E GR+D + G+ A + Sbjct: 246 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 305 Query: 106 NQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQN 139 + T ++ + + +LVA M + Sbjct: 306 MLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKK 339 >1HSO-A nrPDB Length = 374 Score = 32.2 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 49/154 (31%), Gaps = 26/154 (16%) Query: 12 VAVITGGA-------SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 VA +T G+ G+GLS GA ++ N + +AK+LG P + Sbjct: 186 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 245 Query: 65 VTSE------KEVQAALTLAKEKFGRIDVAVNC-------------AGIAVAIKTYHEKK 105 + + + E GR+D + G+ + Sbjct: 246 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 305 Query: 106 NQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQN 139 + T ++ I V +LVA M + Sbjct: 306 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKK 339 >1ID1-A nrPDB Length = 153 Score = 31.8 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 33/88 (37%), Gaps = 2/88 (2%) Query: 28 KRLVGQGATA-VLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA-LTLAKEKFGRI 85 +L +G V+ ++P + + ++LG N P + ++ A + + Sbjct: 20 LQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALS 79 Query: 86 DVAVNCAGIAVAIKTYHEKKNQVHTLED 113 D + A + ++ K V + D Sbjct: 80 DNDADNAFVVLSAKDMSSDVKTVLAVSD 107 >4B1B-A nrPDB Length = 542 Score = 31.8 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 V+ GG G G+++AK GA +L D + +GG C+ Sbjct: 46 VVIGGGPG-GMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGC 94 >1E3J-A nrPDB Length = 352 Score = 31.4 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 33/85 (38%), Gaps = 5/85 (5%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEK 69 G ++ G +GL + GA V E AK G + + + E+ Sbjct: 169 GTTVLVIGAGP-IGLVSVLAAKAYGAFVVCTARSPRRLEV-AKNCGAD-VTLVVDPAKEE 225 Query: 70 EVQAALTLAKEKFGRI-DVAVNCAG 93 E + + + G + +V ++C+G Sbjct: 226 E-SSIIERIRSAIGDLPNVTIDCSG 249 >3DMF-A nrPDB Length = 381 Score = 31.4 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 29/84 (34%), Gaps = 10/84 (11%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 V+G + G G + L GA V ++ + + K L N + A A + Sbjct: 232 VRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSD 288 Query: 68 EKEVQAALTLAKEKFGRIDVAVNC 91 + A + R D+ V Sbjct: 289 -------VDEALTEEARFDIIVTN 305 >3HZZ-A nrPDB Length = 467 Score = 31.4 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 34/95 (35%), Gaps = 13/95 (13%) Query: 3 AAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAP 62 AA++ +G +I G + GLG S A + G + V + + + +G I Sbjct: 242 AAMK--QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDR 298 Query: 63 A----------NVTSEKEVQAALTLAKEKFGRIDV 87 + KE + +E G D+ Sbjct: 299 NAEGYKFWKDEHTQDPKEWKRFGKRIRELTGGEDI 333 >2WEK-A nrPDB Length = 341 Score = 31.4 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 1/47 (2%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG 55 +G ++T A G G A +L + V+ + E K LG Sbjct: 142 EGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEKSAFLKSLG 187 >2GGS-A nrPDB Length = 273 Score = 31.0 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 42/118 (35%), Gaps = 27/118 (22%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 +ITG + LG+ ++ L + V+ +SE + ++T ++ Sbjct: 4 LITGASGQLGIELSRLLSER--HEVIKVYNSSEIQG----------GYKLDLTDFPRLED 51 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRL 131 + R DV +N A + K EK ++ +N +++R Sbjct: 52 FIIK-----KRPDVIINAAAMTDVDKCEIEK----------EKAYKINAEAVRHIVRA 94 >3F6S-A nrPDB Length = 148 Score = 31.0 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 9 KGLVAVITGGASGLGLSTAKRL----VGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 V ++ G ++G S A++L G LL+ ++ E A A Sbjct: 1 MSKVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLADGYDAVLFGCSAW 60 Query: 65 VTSEKEVQAALTLAKEKFGRI 85 + E+Q E+F RI Sbjct: 61 GMEDLEMQDDFLSLFEEFDRI 81 >4KUG-A nrPDB Length = 290 Score = 31.0 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 4/35 (11%), Positives = 12/35 (34%), Gaps = 1/35 (2%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNS 45 + G + +G + +G ++ D+ Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEE 35 >3LK7-A nrPDB Length = 451 Score = 31.0 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 21/59 (35%), Gaps = 1/59 (1%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 + + + ++ G A G + A+ L GA + D + A+ L I Sbjct: 4 ITTFENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVC 61 >3CT4-A nrPDB Length = 332 Score = 31.0 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 37/236 (15%), Positives = 79/236 (33%), Gaps = 45/236 (19%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQG---ATAVLLDVPNSEGETEAKKLGGNCIFAP---- 62 G VA+++GG SG + A VG+G A + + + + A Sbjct: 46 GKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLLI 104 Query: 63 -----ANVTSEKEVQAALTLAKEKFGRI----DVAVNC----------AGIAVAIKTYHE 103 +V + + + + + K +I D+AV AG + K Sbjct: 105 IKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHKILGA 164 Query: 104 KKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVI---------INTA 154 +Q +L++ + + + I+ + + + G+ G + + Sbjct: 165 AAHQEASLDEIKDLAD----KVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIH 220 Query: 155 SVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA-PIGIRVVTIAPGLFATPLLTTL 209 S + + + +Y + + + + GI V G+ ATPL+ Sbjct: 221 SEPGYRREKMKTSYELATELVGKLKEEFKFEAGQKYGILVN----GMGATPLMEQF 272 >4XRR-A nrPDB Length = 456 Score = 31.0 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 29/102 (28%), Gaps = 2/102 (1%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDV-PNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 V+ GA +G A L G+GA V +D P + + A + V Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAATG 77 Query: 73 AALTLA-KEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLED 113 + G DV + G V E Sbjct: 78 RLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQLVAACEQ 119 >3JTJ-A nrPDB Length = 253 Score = 30.6 bits (68), Expect = 0.64, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 5/75 (6%) Query: 28 KRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRI-- 85 +R + GA V++ + + + GG A+ + L E +G Sbjct: 38 ERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRAD---HQSGTERLAEVIEHYGFADD 94 Query: 86 DVAVNCAGIAVAIKT 100 D+ VN G + Sbjct: 95 DIIVNVQGDEPLVPP 109 >4R1U-A nrPDB Length = 349 Score = 30.6 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 17/169 (10%), Positives = 43/169 (25%), Gaps = 38/169 (22%) Query: 4 AVRSVKG--LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE----TEAKKLGGN 57 SV G +TG + K L+ +G T + + E + Sbjct: 19 NTSSVSGGDQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARER 78 Query: 58 CIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRV 117 ++ + +Q+ + C G+ + +++ Sbjct: 79 LTLHKVDLLDLQSIQSVVH-------------GCHGVFHTASPVTDNPDEMLEP------ 119 Query: 118 INVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQA 166 N + V + + ++ T+S+ + Sbjct: 120 -------AVNGTKNVIIASAEAKVR------RVVFTSSIGTVYMDPNTS 155 >3R9I-A nrPDB Length = 260 Score = 30.6 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%), Gaps = 5/38 (13%) Query: 11 LVAVITGGASGLGL-----STAKRLVGQGATAVLLDVP 43 + V+T G G+G + A L +G V++D Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFA 40 >4FP4-A nrPDB Length = 285 Score = 30.6 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 20 SGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAK 79 G+ T + + G G V D +E A LG + + A+V V AL L Sbjct: 98 RGI--KTPRAMYGDGRAIVASDWLIAESIKMAVNLGADVVTYLADVAQRLSVGQALDLEG 155 Query: 80 EK 81 E+ Sbjct: 156 ER 157 >3ZU2-A nrPDB Length = 422 Score = 30.6 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 45/137 (32%), Gaps = 31/137 (22%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATA----VLLDVPNSEGE-------------TEAKK 53 ++ G ++G GL+ A+ G A V + P EG+ A + Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 54 LGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLED 113 G + S++ Q + K+ G++D + ++ T E Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVI--------YSLASPRRTHPKTGEV 175 Query: 114 FQRVI-----NVNLIGT 125 F + VNL G Sbjct: 176 FNSALKPIGNAVNLRGL 192 >3BIC-A nrPDB Length = 762 Score = 30.6 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 28/103 (27%), Gaps = 16/103 (15%) Query: 26 TAKRLVGQGATAVL--LDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFG 83 A G + L E +A + + K + L G Sbjct: 624 IATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLG 683 Query: 84 RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 R D+ V C G+ +D++ + V + F Sbjct: 684 RPDILVMCGGV--------------IPPQDYEFLFEVGVSNVF 712 >4KDR-A nrPDB Length = 223 Score = 30.2 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 29/82 (35%), Gaps = 11/82 (13%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G + G G+ A+ + +GAT LD+ + KL + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQ--VAKLHALESGIQVDY-- 113 Query: 68 EKEVQAALTL-AKEKFGRIDVA 88 VQ + A + G+ DV Sbjct: 114 ---VQETVEEHAAKHAGQYDVV 132 >5JXW-A nrPDB Length = 498 Score = 30.2 bits (67), Expect = 0.85, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 54/167 (32%), Gaps = 23/167 (13%) Query: 5 VRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 ++ + G V+ G +G A+ L G GA ++ ++ + +A G + Sbjct: 266 IQMLAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEI-DPICALQASMEGYQVSVLE-D 322 Query: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV---- 120 V SE ++ G DV I V ++ + + F I+V Sbjct: 323 VVSEADI------FITATGNKDV------ITVEHMRKMKENAYIANIGHFDDEIDVYGLE 370 Query: 121 NLIG--TFNVIRLVAGVM--GQNEPDQGGQRGVIINTASVAAFEGQV 163 N G V + V + +G ++N V Sbjct: 371 NYPGIKVIEVKQNVHKFTFPDTQKSVILLCKGRLVNLGCATGHPPLV 417 >4KDC-A nrPDB Length = 246 Score = 30.2 bits (67), Expect = 0.88, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 29/82 (35%), Gaps = 11/82 (13%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 + G + G G+ A+ + +GAT LD+ + KL + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQ--VAKLHALESGIQVDY-- 113 Query: 68 EKEVQAALTL-AKEKFGRIDVA 88 VQ + A + G+ DV Sbjct: 114 ---VQETVEEHAAKHAGQYDVV 132 >4QUK-A nrPDB Length = 319 Score = 30.2 bits (67), Expect = 0.89, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 49/154 (31%), Gaps = 26/154 (16%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 V +TG + + + L+ +G T ++ + + E+ Sbjct: 2 VVCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKV-------DHLVKLDGAKER-- 52 Query: 72 QAALTLAKEKFGRIDVAV-NCAGIA-VAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVI 129 + G D V C G+ A YH+ K+ +I+ L GT NV+ Sbjct: 53 LQLFKANLLEEGAFDSVVQGCHGVFHTASPFYHDVKDPQA------ELIDPALKGTLNVL 106 Query: 130 RLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQV 163 A ++ T+S+AA Sbjct: 107 NSCAKSPSLK---------RVVLTSSIAAVAYNG 131 >4BKP-A nrPDB Length = 336 Score = 30.2 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 27/72 (37%), Gaps = 20/72 (27%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAP---ANVTSEKE 70 ++TGG+ +G + +++V GA G + +F A++T + Sbjct: 26 LVTGGSGLVGKAI-QKVVADGAGL----------------PGEDWVFVSSKDADLTDTAQ 68 Query: 71 VQAALTLAKEKF 82 +A + Sbjct: 69 TRALFEKVQPTH 80 >1QQV-A nrPDB Length = 67 Score = 30.2 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 15/36 (41%) Query: 84 RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 +DV VN A + +K + EDF+ V Sbjct: 8 PLDVLVNTAAEDLPRGVDPSRKENHLSDEDFKAVFG 43 >1JAY-A nrPDB Length = 212 Score = 30.2 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 14/33 (42%), Gaps = 1/33 (3%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVP 43 VA++ GG LG A RL G V+ Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRR 33 >1YB5-A nrPDB Length = 351 Score = 30.2 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 31/81 (38%), Gaps = 6/81 (7%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 G ++ G + G+GL+ + G +L EG+ + G + +F V Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLK-ILGTAGTEEGQKIVLQNGAHEVFNHREVNYI 228 Query: 69 KEVQAALTLAKEKFGRIDVAV 89 +++ + ID+ + Sbjct: 229 DKIKKYVGE-----KGIDIII 244 >1EDZ-A nrPDB Length = 320 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 21/57 (36%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAP 62 + G ++ + +G A L GAT +DV N + T + L N Sbjct: 173 NRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVE 229 >3Q7E-A nrPDB Length = 349 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 12/90 (13%), Positives = 30/90 (33%), Gaps = 8/90 (8%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 M K V + G +G+ GA V+ +S + K + N + Sbjct: 58 MFHNRHLFKDKVVLDVGSGTGI---LCMFAAKAGARKVIGIECSSISDYAVKIVKANKLD 114 Query: 61 APANVTSEKEVQAALTLAKEKFGRIDVAVN 90 + ++ + + ++D+ ++ Sbjct: 115 HVVTI-----IKGKVEEVELPVEKVDIIIS 139 >4EJ0-A nrPDB Length = 342 Score = 29.9 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 49/164 (29%), Gaps = 27/164 (16%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 ++TG A +G + K L +G T ++ V N + K L + + Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIA-VDNLTRADKFKNL------VDCEIDDYLDKTE 68 Query: 74 ALTL-AKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLV 132 + A+ FG++ +HE D + +++ N F R V Sbjct: 69 FVERFARGDFGKVRAV------------FHEGACSDTMETDGRYMMDNN----FRYSRAV 112 Query: 133 AGVMGQNEPDQGGQRGVIINTAS---VAAFEGQVGQAAYSASKG 173 I S V E + Y SK Sbjct: 113 LDACLAQGAQFLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >2YQ5-A nrPDB Length = 343 Score = 29.9 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 7/78 (8%) Query: 22 LGLSTAKRLVGQGATAVLLDVP-NSEGETEAKKLGGNCIFAPANVTS-----EKEVQAAL 75 +G + A+ GA + DV N E E + + A++ S + + Sbjct: 159 IGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTYTDFDTVLKEADIVSLHTPLFPSTENMI 218 Query: 76 -TLAKEKFGRIDVAVNCA 92 ++ + +NCA Sbjct: 219 GEKQLKEMKKSAYLINCA 236 >3VR3-A nrPDB Length = 600 Score = 29.9 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 23/63 (36%) Query: 23 GLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKF 82 G++ A+ G ++ S +++ G P + + + L E+ Sbjct: 317 GITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERS 376 Query: 83 GRI 85 GR+ Sbjct: 377 GRV 379 >3MMP-A nrPDB Length = 678 Score = 29.9 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 50/153 (32%), Gaps = 18/153 (11%) Query: 91 CAGIAVAIKTYHEKKNQVHTLEDF-QRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 GI + + + + + F +V++ + G + ++ + + G Sbjct: 69 NYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGE 128 Query: 150 IINTASVAAFEGQVGQA--------AYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLF 201 IN VAA EG V + A+KG + IA +A P Sbjct: 129 NINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASK-------PEFI 181 Query: 202 ATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYA 234 ++ + V Q+ + G P E A Sbjct: 182 KPEDVSA--EVVEKEYQVQLDIAMQSGKPKEIA 212 >4PZE-A nrPDB Length = 284 Score = 29.9 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 32/222 (14%), Positives = 65/222 (29%), Gaps = 23/222 (10%) Query: 18 GASGLGLSTAKRLVGQGATAVLLDVPNS----EGETEAKKLGGNCIFAPANVTSEKEVQA 73 GA +G A+ G V++D+ ++ T A L + A Sbjct: 10 GAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEADKASALA 69 Query: 74 ALT--LAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRL 131 + + + D+ + A +K K+ E+ +I N + ++ +L Sbjct: 70 RIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENV--IIASN-TSSISITKL 126 Query: 132 VAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGI 191 A + + A V G + + ++ L I Sbjct: 127 AAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSD---TTHAAVEALSK----QLGKYPI 179 Query: 192 RVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEY 233 V +PG +L + ++ + L P E Sbjct: 180 TVKN-SPGFVVNRILCPMINE------AFCVLGEGLASPEEI 214 >1DB3-A nrPDB Length = 372 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 23/77 (29%), Gaps = 8/77 (10%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETE--------AKKLGGNCIFAP 62 VA+ITG G A+ L+ +G + S TE Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 63 ANVTSEKEVQAALTLAK 79 +++ + L + Sbjct: 62 GDLSDTSNLTRILREVQ 78 >5GXF-A nrPDB Length = 330 Score = 29.5 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 12/36 (33%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGE 48 ++TG A G+G L G + + Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >6C55-A nrPDB Length = 340 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 25/73 (34%), Gaps = 2/73 (2%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67 ++G + G S G + A+ L G V+ P + AK+ G + V Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDK-AKEDGFDVFPVAEAVKQ 72 Query: 68 EKEVQAALTLAKE 80 + L + Sbjct: 73 ADVIMVLLPDEIQ 85 >4E0B-A nrPDB Length = 313 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 4/36 (11%) Query: 11 LVAVITGGASGLGLSTAKRL---VGQGATAVLLDVP 43 VAVI G A G+G + A L + G+ L D+ Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIA 39 >3FBG-A nrPDB Length = 346 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 3/52 (5%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQ-GATAVLLDVPNSEGETEAKKLGGNCI 59 +G +I GA G+G S A ++ G + N E KK+G + + Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIEWT-KKMGADIV 199 >3X2F-A nrPDB Length = 411 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 23/82 (28%), Gaps = 11/82 (13%) Query: 8 VKGLVAVITGGASG-LGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 V G V+ G G A R G GA ++ +V + I V Sbjct: 195 VAGKNVVV--AGYGWCGRGIALRAAGLGARVIVTEVDPVKA--------VEAIMDGFTVM 244 Query: 67 SEKEVQAALTLAKEKFGRIDVA 88 KE G DV Sbjct: 245 PMKEAVKIADFVITASGNTDVL 266 >2BC1-A nrPDB Length = 490 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 2/32 (6%) Query: 11 LVAVITGGASGLGLSTAKRLVGQGATAVLLDV 42 VAV+ GA +G+ A+ +G VL+DV Sbjct: 196 RVAVV--GAGYIGVELAEAFQRKGKEVVLIDV 225 >3DQQ-A nrPDB Length = 421 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%) Query: 150 IINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTL 209 I TAS A Q + + + + +A LA GI +A G + + +L Sbjct: 313 ISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGGETSGVVTQSL 372 Query: 210 P 210 Sbjct: 373 G 373 >4GBJ-A nrPDB Length = 297 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 27/75 (36%), Gaps = 13/75 (17%) Query: 22 LGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN-----------VTSEKE 70 LG A+ L+ G V+ + S+ E KLG + + + + Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKAEPL-TKLGATVVENAIDAITPGGIVFSVLADDAA 74 Query: 71 VQAALT-LAKEKFGR 84 V+ + EK G+ Sbjct: 75 VEELFSMELVEKLGK 89 >5KXJ-A nrPDB Length = 557 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 15/82 (18%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 +I G + GLS A RL + VL P SEG T + G +F + + Sbjct: 11 VLIIGSGAA-GLSLALRLAEKHKVIVLSKGPVSEGSTFYAQGGIAAVFDETD-----SIA 64 Query: 73 AALTLAKEKFGRIDVAVNCAGI 94 + + D + AGI Sbjct: 65 SHVE---------DTLIAGAGI 77 >5B1I-A nrPDB Length = 311 Score = 29.1 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 7 SVKGLVAVI--TGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 V +I T G +G+GL+ A + V+ + + E + + LG + P Sbjct: 58 RVNAKTTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTP-- 115 Query: 65 VTSEKEVQAALTLAKE 80 SE+ ++ A+ A+ Sbjct: 116 --SEEGIKGAIRKAEA 129 >7REQ-A nrPDB Length = 727 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 28/92 (30%), Gaps = 3/92 (3%) Query: 17 GGASGLGLSTAKRLVGQGATAVL--LDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA 74 G G A G + L E +A + + + + + A Sbjct: 608 GHDRGQ-KVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPA 666 Query: 75 LTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKN 106 L +K GR D+ + G+ +K+ Sbjct: 667 LRKELDKLGRPDILITVGGVIPEQDFDELRKD 698 >3K4W-A nrPDB Length = 291 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 32/84 (38%), Gaps = 18/84 (21%) Query: 136 MGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKG---------GIVGMTLPIAR-- 184 M +QG G +SV AA +K I T A Sbjct: 56 MAAAGIEQGVCVGR---NSSVLGSVSNADVAA--VAKAYPDKFHPVGSIEAATRKEAMAQ 110 Query: 185 --DLAPIGIRVVTIAPGLFATPLL 206 ++ +GIR+V + PG++ATP+ Sbjct: 111 MQEILDLGIRIVNLEPGVWATPMH 134 >6GBN-A nrPDB Length = 438 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVP 43 + G VAV+ G +G +A L G GA ++ ++ Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEID 251 >2D0I-A nrPDB Length = 333 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 3/54 (5%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGN 57 + S+ G I G +G + A+RL+ G L K+L Sbjct: 140 RIESLYGKKVGILG-MGAIGKAIARRLIPFG--VKLYYWSRHRKVNVEKELKAR 190 >3WJN-A nrPDB Length = 337 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 33/107 (30%), Gaps = 11/107 (10%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 +++GG + A L A AV + + +V E +++ Sbjct: 53 IVSGGGKRIRPMIAV-LA---ARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRR 108 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV 120 A FG A + + + Q+ T +V+ V Sbjct: 109 GKATANAAFG-------NAASVLVGDFIYTRAFQMMTSLGSLKVLEV 148 >4A5O-A nrPDB Length = 286 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 24/61 (39%) Query: 1 MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF 60 +A+ + G+ AV+ G ++ +G A L+ G T + + + + Sbjct: 152 LASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSRADLVVVA 211 Query: 61 A 61 A Sbjct: 212 A 212 >3H0K-A nrPDB Length = 178 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 20/48 (41%), Gaps = 2/48 (4%) Query: 11 LVAVITGGASGLGL-STAKRLVGQGATAVLLDVPNSEGETEAKKLGGN 57 V +ITG G G AK L +GA +++ + + K G Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGER 47 >1NHQ-A nrPDB Length = 447 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 15/31 (48%), Gaps = 2/31 (6%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDV 42 V VI G+ +G+ A+ G ++D+ Sbjct: 152 VVVI--GSGYIGIEAAEAFAKAGKKVTVIDI 180 >1YXY-A nrPDB Length = 234 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 156 VAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTI 196 + + + G+ YS + GGI+ + A++ +GIR ++ Sbjct: 19 IVSCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >4B3J-A nrPDB Length = 736 Score = 28.3 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 39/139 (28%), Gaps = 33/139 (23%) Query: 18 GASGLGLSTAKRLVGQGATAVLLDVP----------NSEGETEAKKLGGNC--------- 58 GA +G A G VL DV + + E +A + G Sbjct: 348 GAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSDALLA 407 Query: 59 -IFAPANVTSEKEVQAALTLAKEK-------FGRI-DVAVNCA--GIAVAIKTYHEKKNQ 107 I A+ K V + E FG I D+ A G + Sbjct: 408 RITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNAILGSNTSTLPITGLATG 467 Query: 108 VHTLEDFQRVINVNLIGTF 126 V EDF I ++ Sbjct: 468 VKRQEDF---IGIHFFSPV 483 >2CF5-A nrPDB Length = 357 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 22/61 (36%), Gaps = 3/61 (4%) Query: 22 LGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEK 81 +G+ AK G ++ N + E + LG + ++ E+ +L + Sbjct: 195 MGVKIAK---AMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAKMSELADSLDYVIDT 251 Query: 82 F 82 Sbjct: 252 V 252 >4B4V-A nrPDB Length = 303 Score = 27.9 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 17/46 (36%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL 54 G AV+ G ++ LG A L+ AT + K+ Sbjct: 178 AGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQA 223 >3DC2-A nrPDB Length = 529 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 26/77 (33%), Gaps = 3/77 (3%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEK 69 G + G +G A+R+ GA V D S A +LG + + Sbjct: 142 GKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPAR--AAQLGIELLSLDDLLARAD 198 Query: 70 EVQAALTLAKEKFGRID 86 + L E G ID Sbjct: 199 FISVHLPKTPETAGLID 215 >3H9U-A nrPDB Length = 436 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 41/158 (25%), Gaps = 21/158 (13%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 G A + G +G A L G GA V+ +V A + G + Sbjct: 210 AGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAME-GYQVLLV------- 260 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV-----NLI 123 ++V + G D+ I V + F I V N Sbjct: 261 EDVVEEAHIFVTTTGNDDI------ITSEHFPRMRDDAIVCNIGHFDTEIQVAWLKANAK 314 Query: 124 GTFNVIRLVAGV-MGQNEPDQGGQRGVIINTASVAAFE 160 V V M G ++N + Sbjct: 315 ERVEVKPQVDRYTMANGRHIILLAEGRLVNLGCASGHP 352 >4PC7-C nrPDB Length = 282 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 50/153 (32%), Gaps = 18/153 (11%) Query: 91 CAGIAVAIKTYHEKKNQVHTLEDF-QRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 GI + + + + + F +V++ + G + ++ + + G Sbjct: 68 NYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGE 127 Query: 150 IINTASVAAFEGQVGQA--------AYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLF 201 IN VAA EG V + A+KG + IA +A P Sbjct: 128 NINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASK-------PEFI 180 Query: 202 ATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYA 234 ++ + V Q+ + G P E A Sbjct: 181 KPEDVSA--EVVEKEYQVQLDIAMQSGKPKEIA 211 >2IUU-A nrPDB Length = 491 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 2/44 (4%) Query: 175 IVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLA 218 I + +AR LA I +RVV + PG T + +P++ R + Sbjct: 136 ISNLAKDLARSLAVISVRVVEVIPG--KTTVGIEIPNEDRQMVR 177 >4BM5-A nrPDB Length = 348 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 40/121 (33%), Gaps = 23/121 (19%) Query: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 +V + V+ A + G I + ++ +N + +E+ Q V VNL Sbjct: 7 DVGDDPFVRRAGAFLGIEAGTITIELSN-------LIDFYIRNGILEMENEQAVYPVNLR 59 Query: 124 GTF-----------NVIRLVA---GVMGQNEPDQGGQRGVIINTAS--VAAFEGQVGQAA 167 G F +I+ A + + G I+ S V A +G Sbjct: 60 GVFDLNILQEMYRQYLIQSFAAKSRTEKERLFNNLAHLGNILGLTSAEVNAIHSNIGSVI 119 Query: 168 Y 168 Y Sbjct: 120 Y 120 >4R16-A nrPDB Length = 418 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 10/24 (41%) Query: 22 LGLSTAKRLVGQGATAVLLDVPNS 45 +GL TA G V D+ + Sbjct: 11 IGLPTAIMFASSGYDVVGYDIRSE 34 >5TEN-A nrPDB Length = 269 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 37/106 (34%), Gaps = 4/106 (3%) Query: 17 GGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAAL- 75 G A G+G + A + + + + GE ++G I A V + A + Sbjct: 165 GTAIGMGEAIAGAMGNKLSDVAVYAREGITGERTKDEIGFATIRAGDIVGEHTAMFADIG 224 Query: 76 TLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 + D G A HEK +T+ D V+ +N Sbjct: 225 ERVEITHKATDRMTFANGAVKAAVWLHEKPAGFYTMTD---VLGLN 267 >1EQ2-A nrPDB Length = 310 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 13/21 (61%) Query: 14 VITGGASGLGLSTAKRLVGQG 34 ++TGGA +G + K L +G Sbjct: 3 IVTGGAGFIGSNIVKALNDKG 23 >2X86-A nrPDB Length = 357 Score = 27.9 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 13/21 (61%) Query: 14 VITGGASGLGLSTAKRLVGQG 34 ++TGGA +G + K L +G Sbjct: 50 IVTGGAGFIGSNIVKALNDKG 70 >2Q4W-A nrPDB Length = 524 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 36/109 (33%), Gaps = 13/109 (11%) Query: 16 TGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAAL 75 T A G G S + + +G V + E L G A +V+ + L Sbjct: 88 TVAARGNGHSINGQAMAEGGLVVDMSTTAEN-HFEVGYLSGGDATAFVDVSGGALWEDVL 146 Query: 76 TLAKEKFGRI-----DVA-------VNCAGIAVAIKTYHEKKNQVHTLE 112 ++G D ++ AG++ Y + + V L+ Sbjct: 147 KRCVSEYGLAPRSWTDYLGLTVGGTLSNAGVSGQAFRYGPQTSNVTELD 195 >2IUT-A nrPDB Length = 574 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 2/44 (4%) Query: 175 IVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLA 218 I + +AR LA I +RVV + PG T + +P++ R + Sbjct: 136 ISNLAKDLARSLAVISVRVVEVIPG--KTTVGIEIPNEDRQMVR 177 >2JLA-A nrPDB Length = 558 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 16/41 (39%), Gaps = 4/41 (9%) Query: 175 IVGMTLPIAR----DLAPIGIRVVTIAPGLFATPLLTTLPD 211 + A L G+R + IAPG +TPL + Sbjct: 5 VSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAE 45 >5UOG-A nrPDB Length = 344 Score = 27.9 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEG 47 S++G + G +GL+ A+RL G + EG Sbjct: 161 SLRGRTVGLFGLGR-IGLAIARRLEAFGVSIAYHTRTPREG 200 >1X74-A nrPDB Length = 360 Score = 27.5 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 4/72 (5%) Query: 18 GASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTL 77 G G A L GA V +D P+S + N A++ S++ ++ AL L Sbjct: 14 AGIGPGPHAAMILGDLGADVVRIDRPSSVDGISRDAMLRNRRIVTADLKSDQGLELALKL 73 Query: 78 AKEKFGRIDVAV 89 + DV + Sbjct: 74 IAKA----DVLI 81 >1P0F-A nrPDB Length = 373 Score = 27.5 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 4/76 (5%) Query: 18 GASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTL 77 G G+G S GA+ ++ + + +A +LG P + + + Sbjct: 199 GLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKP--IYEVI-- 254 Query: 78 AKEKFGRIDVAVNCAG 93 ++ G +D AV CAG Sbjct: 255 CEKTNGGVDYAVECAG 270 >6MVR-A nrPDB Length = 767 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 11/92 (11%) Query: 9 KGLVAVITG-GASG--LGLSTAKRLVGQGATAVLLDVPNSE---GETEAKKLGGNCIFAP 62 G+V ++TG GA G + + ++ G+TAV + + G+ + +LGG + Sbjct: 212 AGVVNIVTGDGAVGEMIVTAQVDKVAFTGSTAVGRRIREATAGTGKALSLELGGKGPYVV 271 Query: 63 ANVTSEKE-VQAALTLAKEKFGRIDVAVNCAG 93 + V+ + G+ V CAG Sbjct: 272 CDDADIDSAVEGLVDAIWFNQGQ----VCCAG 299 >4B4O-A nrPDB Length = 298 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 19/54 (35%), Gaps = 1/54 (1%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 ++ GG +G + + L +G L+ G +L + + + Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLP-SCDAA 55 >3R7T-A nrPDB Length = 419 Score = 27.5 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 22/60 (36%), Gaps = 1/60 (1%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 A +KG A+ T G G+G S A ++ G L P E K N F Sbjct: 116 AKEKLKGKNAIGTTG-KGIGPSYADKINRTGHRVGELLEPQRLCEALIKDFEANKTFFEM 174 >3SC6-A nrPDB Length = 287 Score = 27.5 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 22/164 (13%), Positives = 45/164 (27%), Gaps = 43/164 (26%) Query: 36 TAVLLDVPNSEGETEAKKLGGNCIFA------PANVTSEKEVQAALTLAKEKFGRIDVAV 89 ++ G+ ++L ++T+ +VQ + R + + Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKLLDITNISQVQQVVQEI-----RPHIII 61 Query: 90 NCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGV 149 +CA + E+ +N IG NV VA + Sbjct: 62 HCAAYTKVDQAEKER----------DLAYVINAIGARNV--AVASQLV---------GAK 100 Query: 150 IINTASVAAFEG-----------QVGQAAYSASKGGIVGMTLPI 182 ++ ++ F+G Y ASK + Sbjct: 101 LVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >4OFX-A nrPDB Length = 319 Score = 27.5 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 10/77 (12%), Positives = 24/77 (31%), Gaps = 6/77 (7%) Query: 16 TGGASGLGLSTAKRLVGQGATAVLL--DVPNSEGETEAKKLGGNCIFAPANVT--SEKEV 71 T G +G+G A +G ++ + + E + + LG P + Sbjct: 73 TSGNTGIG--IALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAAYDDPESH 130 Query: 72 QAALTLAKEKFGRIDVA 88 + ++ + Sbjct: 131 ISLAKRLNQEIPNSYIL 147 >5TC4-A nrPDB Length = 316 Score = 27.5 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 35/111 (31%), Gaps = 23/111 (20%) Query: 10 GLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEK 69 G V+ G + +G+ A L GA ++ GG + T Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH---------------ERPGG-------DATVTI 196 Query: 70 EVQAALTLAKEKFGRI-DVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 + +K + D+ ++ AGI I K+ RV + Sbjct: 197 SHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHD 247 >5ZZM-A nrPDB Length = 426 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 24/58 (41%), Gaps = 14/58 (24%) Query: 2 AAAVRSVKGLVAVITGGAS--------GLGLS--TAKRLVGQGATAVLLDVPNSEGET 49 +A V +++ VITG G G + A+ + GA+ VL D S + Sbjct: 36 SAGVEALQ----VITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQE 89 >4Z6K-A nrPDB Length = 346 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 41/137 (29%), Gaps = 19/137 (13%) Query: 24 LSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFG 83 L+ AK+L GA + E K++GG V+ A A Sbjct: 201 LAFAKKL---GAKVTVNAKNTDPAEYLQKEIGGAHGALVTAVS-----AKAFDQALSMLR 252 Query: 84 RIDVAVNCAGIAVAIKT----------YHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVA 133 R V G+ + + V T D Q +++ G Sbjct: 253 RGGTLVCN-GLPPGDFPVSIFDTVLNGITIRGSIVGTRLDLQESLDMAAAGKVKATVTAE 311 Query: 134 GVMGQNEPDQGGQRGVI 150 + N+ + ++G I Sbjct: 312 PLENINDIFERMRQGKI 328 >4NFY-A nrPDB Length = 307 Score = 27.5 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 39/112 (34%), Gaps = 15/112 (13%) Query: 11 LVAVIT------GGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPAN 64 + VIT G+ L G V+++ + + + + + ++ Sbjct: 2 KIVVITEKPFAENAVKGI-REI---LEKAGHEVVMIEKYKKKEDVIERIKDADGVIVRSD 57 Query: 65 VTSEKEVQA-----ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTL 111 E+ ++A + A + ID+ G V + T + +N V L Sbjct: 58 KIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRNGVAEL 109 >3S8M-A nrPDB Length = 422 Score = 27.5 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 31/96 (32%), Gaps = 17/96 (17%) Query: 11 LVAVITGGASGLGLS----TAKRLVGQ--G--------ATAVLLD--VPNSEGETEAKKL 54 ++ G +SG GL+ A G A+ ++ + AK Sbjct: 62 KKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAA 121 Query: 55 GGNCIFAPANVTSEKEVQAALTLAKEKFGR-IDVAV 89 G + S+ + L K + G +D+ V Sbjct: 122 GLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVV 157 >5XW3-A nrPDB Length = 315 Score = 27.5 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 16 TGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAAL 75 T G +G+GL+ A + + + E + K LG + P E+ + A+ Sbjct: 71 TAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPT----EQGMTGAI 126 Query: 76 TLAKE 80 AKE Sbjct: 127 AKAKE 131 >6BZ0-A nrPDB Length = 480 Score = 27.2 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 18/50 (36%), Gaps = 4/50 (8%) Query: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPA 63 V+ GG G G A R G ++ G+ LGG C+ Sbjct: 11 VVIGGGPG-GYEAAIRAAQLGFKVACIEKRIHNGKP---SLGGTCLNVGC 56 >4WEQ-A nrPDB Length = 341 Score = 27.2 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 13/45 (28%), Gaps = 2/45 (4%) Query: 22 LGLSTAKRLVGQGATAVLLDVPNS--EGETEAKKLGGNCIFAPAN 64 LG A++L G + EG G + + Sbjct: 172 LGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGRTD 216 >3G1U-A nrPDB Length = 437 Score = 27.2 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 41/158 (25%), Gaps = 21/158 (13%) Query: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 G + G +G A L GA V+ +V + + V Sbjct: 211 AGKTCCVCGYGD-VGKGCAAALRAFGARVVVTEVDPINALQASME--------GYQVALV 261 Query: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV-----NLI 123 ++V A + G D+ I + V + F I V N Sbjct: 262 EDVMADAHIFVTTTGNDDI------ITSDHFPHMRDDAIVCNIGHFDTEIQVGWLEANAK 315 Query: 124 GTFNVIRLVAGV-MGQNEPDQGGQRGVIINTASVAAFE 160 + V M +G ++N + Sbjct: 316 EHVEIKPQVDRYTMENGRHIILLAKGRLVNLGCASGHP 353 >5T57-A nrPDB Length = 296 Score = 27.2 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 1/74 (1%) Query: 6 RSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANV 65 +K +A+ G +G+ AK L+ ++V + +LG C+ A + Sbjct: 19 SHMKEKIALF-GAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAAL 77 Query: 66 TSEKEVQAALTLAK 79 + V A+ Sbjct: 78 DNVDVVILAVPDTI 91 >3N58-A nrPDB Length = 464 Score = 27.2 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 28/84 (33%), Gaps = 21/84 (25%) Query: 8 VKGLVAVITGGASGLGLSTAKRLVGQGAT--------------------AVLLDVPNSEG 47 + G VAV+ G +G +A+ L G GA V LD S Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTA 303 Query: 48 ETEAKKLGGNCIFAPANVTSEKEV 71 + G + ++ K++ Sbjct: 304 DIVVTTTGNKDVITIDHMRKMKDM 327 >2EEZ-A nrPDB Length = 369 Score = 27.2 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 6/80 (7%) Query: 13 AVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQ 72 VI GG + +G + AK +G GA +LDV + + GG I A +E ++ Sbjct: 169 VVILGGGT-VGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTA---TEANIK 224 Query: 73 AALTLAKEKFGRIDVAVNCA 92 ++ A G V V A Sbjct: 225 KSVQHADLLIGA--VLVPGA 242 >4TSK-A nrPDB Length = 350 Score = 27.2 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 19/58 (32%), Gaps = 2/58 (3%) Query: 4 AVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFA 61 +++ + + G S G + A+ L G V+ P S G + Sbjct: 11 SIQPLADKRIAVIGYGS-QGHAHAQNLRDSGFDVVIGLRPGSSWAKAEAD-GFRVMAV 66 >5H7J-A nrPDB Length = 743 Score = 27.2 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 16/30 (53%) Query: 205 LLTTLPDKVRNFLASQVPFPSRLGDPAEYA 234 ++ +PD++ N + + R+ +P E A Sbjct: 493 VVEPMPDEIYNAIKEGIIPEGRVKNPKEVA 522 >4Y4N-A nrPDB Length = 286 Score = 26.8 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVP 43 VA++ GG SGL + A+ + +G V+L+ Sbjct: 55 VAIVGGGPSGL--TAARYIAKEGYKVVVLERH 84 >1XDW-A nrPDB Length = 331 Score = 26.8 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 9/25 (36%), Positives = 12/25 (48%) Query: 18 GASGLGLSTAKRLVGQGATAVLLDV 42 G +G A+ G GAT + DV Sbjct: 153 GLGRIGRVAAQIFHGMGATVIGEDV 177 >1UUF-A nrPDB Length = 369 Score = 26.8 bits (58), Expect = 9.1, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 19/62 (30%), Gaps = 6/62 (9%) Query: 21 GLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKE 80 G+ L+ A GA V ++ E AK LG + + N + Sbjct: 210 GIKLAHAM-----GAHVVAFTTSEAKREA-AKALGADEVVNSRNADEMAAHLKSFDFILN 263 Query: 81 KF 82 Sbjct: 264 TV 265 >2R5U-A nrPDB Length = 200 Score = 26.8 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 24/73 (32%), Gaps = 4/73 (5%) Query: 24 LSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE---KEVQAALTLAKE 80 + +RLV G V +EG + ++ +V ++ A L + Sbjct: 129 KALLRRLVEAGTRVVQYGYAGAEG-ADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQP 187 Query: 81 KFGRIDVAVNCAG 93 ID + G Sbjct: 188 TMDEIDAIASSGG 200 >2EGU-A nrPDB Length = 308 Score = 26.8 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 42/106 (39%), Gaps = 15/106 (14%) Query: 16 TGGASGLGLSTAKRLVGQGATAVLL--DVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 T G +G+GL+ +G AVL+ D + E + G + P + ++ Sbjct: 72 TSGNTGIGLAMVA--AAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPG----AQGMRG 125 Query: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 A+ A+E V G + + +E ++H L + ++ Sbjct: 126 AIAKAEE-------LVREHGYFMPQQFKNEANPEIHRLTTGKEIVE 164 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.152 0.441 Lambda K H 0.267 0.0464 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,493,260 Number of Sequences: 36641 Number of extensions: 514573 Number of successful extensions: 3481 Number of sequences better than 10.0: 435 Number of HSP's better than 10.0 without gapping: 406 Number of HSP's successfully gapped in prelim test: 208 Number of HSP's that attempted gapping in prelim test: 2048 Number of HSP's gapped (non-prelim): 658 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.8 bits)