BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O65202 (664 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1W07-A nrPDB 1377 0.0 2FON-A nrPDB 1145 0.0 1IS2-A nrPDB 555 e-158 5K3G-A nrPDB 436 e-122 5K3J-A nrPDB 414 e-116 5Y9D-A nrPDB 387 e-108 5YS9-A nrPDB 371 e-103 3MDE-A nrPDB 61 1e-09 1UKW-A nrPDB 60 4e-09 3SF6-A nrPDB 58 1e-08 2VIG-A nrPDB 57 3e-08 1JQI-A nrPDB 56 5e-08 2A1T-A nrPDB 56 5e-08 3PFD-A nrPDB 53 4e-07 4L1F-A nrPDB 52 6e-07 4N5F-A nrPDB 52 9e-07 2IX5-A nrPDB 52 9e-07 6FAH-C nrPDB 52 1e-06 3MPI-A nrPDB 50 2e-06 5LNX-A nrPDB 50 5e-06 3SWO-A nrPDB 49 9e-06 3OWA-A nrPDB 47 2e-05 3B96-A nrPDB 47 3e-05 6ES9-A nrPDB 47 3e-05 5IDU-A nrPDB 47 3e-05 1SIR-A nrPDB 46 4e-05 3NF4-A nrPDB 46 5e-05 4U83-A nrPDB 45 8e-05 1RX0-A nrPDB 44 2e-04 2PG0-A nrPDB 44 2e-04 5OL2-C nrPDB 44 3e-04 2Z1Q-A nrPDB 44 3e-04 4IRN-A nrPDB 44 3e-04 5JSC-A nrPDB 41 0.001 4HR3-A nrPDB 40 0.003 4W9U-A nrPDB 40 0.004 3GNC-A nrPDB 39 0.005 4M9A-A nrPDB 39 0.006 4O5M-A nrPDB 37 0.026 4IV6-A nrPDB 37 0.030 2WBI-A nrPDB 35 0.081 2EBA-A nrPDB 35 0.11 5ZW7-A nrPDB 35 0.13 3R7K-A nrPDB 33 0.36 1IVH-A nrPDB 32 0.62 3U33-A nrPDB 31 1.8 1KYQ-A nrPDB 30 3.2 5LON-B nrPDB 30 3.4 5O9W-A nrPDB 29 6.0 2DVL-A nrPDB 29 8.5 5EZ3-A nrPDB 28 8.8 5KUC-A nrPDB 28 9.1 >1W07-A nrPDB Length = 659 Score = 1377 bits (3563), Expect = 0.0, Method: Compositional matrix adjust. Identities = 658/659 (99%), Positives = 658/659 (99%) Query: 1 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE 60 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE Sbjct: 1 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE 60 Query: 61 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK Sbjct: 61 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 Query: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTAT DPKTDEFVIHTPTQTASKWWPGGLG Sbjct: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQTASKWWPGGLG 180 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG Sbjct: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV Sbjct: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE Sbjct: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 Query: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA Sbjct: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 Query: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP Sbjct: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 Query: 481 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE 540 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE Sbjct: 481 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE 540 Query: 541 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA 600 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA Sbjct: 541 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA 600 Query: 601 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQL 659 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQL Sbjct: 601 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQL 659 >2FON-A nrPDB Length = 683 Score = 1145 bits (2961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 532/664 (80%), Positives = 604/664 (90%) Query: 1 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE 60 MEG+D+LADER KA FDV++MKIVWAGSRH FE++DRI++LVASDP F K R L RKE Sbjct: 20 MEGVDYLADERKKAGFDVDEMKIVWAGSRHDFELTDRISKLVASDPGFSKEGRTMLPRKE 79 Query: 61 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 LFK+TLRK A+A+KRIIELRL++EEA LR ++D+PA+ DLHWGMF+PAIKGQGT++QQ+ Sbjct: 80 LFKNTLRKAAYAWKRIIELRLSQEEATMLRRYVDEPAFTDLHWGMFIPAIKGQGTDKQQE 139 Query: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 KWL LA KMQIIGCYAQTELGHGSNVQGLETTATFDP+TDEFVIH+PT T+SKWWPGGLG Sbjct: 140 KWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVIHSPTLTSSKWWPGGLG 199 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 KVSTHAVVYARLIT+GKDYG++GFIVQLRSLEDH PLP +TVGDIG K GNGAYNSMDNG Sbjct: 200 KVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVTVGDIGMKFGNGAYNSMDNG 259 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 L FDHVRIPRDQMLMR+S+VT+EG+YV SD+P+QL+YGTMVYVRQ+IVADAS A+SRAV Sbjct: 260 VLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTMVYVRQSIVADASLAMSRAV 319 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 CIATRYSAVRRQFG+ NGG ETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVT+ Sbjct: 320 CIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTQ 379 Query: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 RLAA+DF+TLPEAHACTAGLKSLTT+ATADGIEECRKLCGGHGYL SGLPELFAVYVPA Sbjct: 380 RLAANDFSTLPEAHACTAGLKSLTTSATADGIEECRKLCGGHGYLCSSGLPELFAVYVPA 439 Query: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 CTYEGDNVVLQLQVARFLMKT++QLG+GK PVGT +YMGR HL+QCRS V++AEDWL P Sbjct: 440 CTYEGDNVVLQLQVARFLMKTISQLGTGKKPVGTVSYMGRIEHLMQCRSDVKQAEDWLKP 499 Query: 481 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE 540 VLEAFEAR+ RM+V CAKNLSKFENQE+GF EL ADLVEAA+AHCQLIVVSK+I KL+ Sbjct: 500 SAVLEAFEARSARMSVACAKNLSKFENQEEGFAELAADLVEAAVAHCQLIVVSKYIEKLQ 559 Query: 541 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA 600 Q+I GKGVK+QL LC IY+L++LHKH GDFL T IT KQ SLANDQLR+LY+Q+RPNA Sbjct: 560 QNIPGKGVKQQLEVLCGIYSLFILHKHQGDFLGTGYITSKQGSLANDQLRALYSQLRPNA 619 Query: 601 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQLR 660 V+LVDAFNYTDHYL S+LGRYDGNVYPKL+E A KDPLN S + DG+ EY+RP+L+QQLR Sbjct: 620 VSLVDAFNYTDHYLGSILGRYDGNVYPKLYEAAWKDPLNKSDIADGFHEYIRPLLKQQLR 679 Query: 661 TARL 664 TA+L Sbjct: 680 TAKL 683 >1IS2-A nrPDB Length = 661 Score = 555 bits (1431), Expect = e-158, Method: Compositional matrix adjust. Identities = 300/668 (44%), Positives = 415/668 (62%), Gaps = 26/668 (3%) Query: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 L ER A F+ E + + GS I L+ +DP F+ + L+R + ++ + Sbjct: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 Query: 67 RKCAHAFKRIIELRLNE-EEAGRLRHFIDQ--PAYVDLHWGMFVPAIKGQGTEEQQKKWL 123 +K A K++ E +++ EE ++ + + P +DLH GMF+P + Q T EQQ+++ Sbjct: 65 KKSATMVKKMREYGISDPEEIMWFKNSVHRGHPEPLDLHLGMFLPTLLHQATAEQQERFF 124 Query: 124 SLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVS 183 A ++I G YAQTE+GHG++++GLETTAT+DPKT EF++++PT T+ KWWPGGLGK S Sbjct: 125 MPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 Query: 184 THAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLM 243 HA+V A+LIT G+ YG+H F+V +R + H PLP ITVGDIG K G Y MDNG+L Sbjct: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241 Query: 244 FDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIA 303 D+ RIPR+ MLM+ ++V +G YV + +L YGTMV+VR +V +A+ +LS+A IA Sbjct: 242 MDNYRIPRENMLMKYAQVKPDGTYV-KPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 Query: 304 TRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLA 363 RYSAVRRQ E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + E + Sbjct: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 Query: 364 ASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTY 423 D + LPE HA TAGLK+ TT GIEECR CGGHGY SG+P ++ + PACT+ Sbjct: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 Query: 424 EGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNPDVV 483 EG+N V+ LQ ARFLMK Q+ SGK+ G +Y+ L R Q+ W P +V Sbjct: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLN---DLPSQRIQPQQVAVW--PTMV 475 Query: 484 --------LEAFEARALRMAVTCAKNL----SKFENQEQGFQELLADLVEAAIAHCQLIV 531 EA++ RA R+ AKNL S +++E + DLV A+ AHC +V Sbjct: 476 DINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVV 535 Query: 532 VSKFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRS 591 V F KL + I K V+ L NLC +Y+LY + + GDFL + IT Q S N ++ Sbjct: 536 VKVFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILE 594 Query: 592 LYTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYL 651 L T +RPNAVALVDAF++ D L SVLGRYDGNVY LFE A K PLN + V + Y ++L Sbjct: 595 LLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHL 654 Query: 652 RPVLQQQL 659 +P LQ +L Sbjct: 655 KP-LQSKL 661 >5K3G-A nrPDB Length = 684 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 255/664 (38%), Positives = 378/664 (56%), Gaps = 24/664 (3%) Query: 7 LADERNKAEFDVEDMKI-VWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKST 65 L ER A FD M ++ G A + A+L + + ++R+E + Sbjct: 16 LTAERLTATFDTHAMAAQIYGGEMRARRRREITAKLAEIPELHDSMPLPYMTREEKIMES 75 Query: 66 LRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVD-----LHWGMFVPAIKGQGTEEQQK 120 RK +R+ E+ ++ +AG L H ++ ++ LH MF+PA+ Q ++EQQ Sbjct: 76 ARKLTVLTQRMSEI-IDPTDAGELYHLNNEVLGIEGNPMALHGVMFIPALNAQASDEQQA 134 Query: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 KWL A + +IIG YAQTE+GHG+N+Q LETTAT+D T EFV+HTP TA KWWPG LG Sbjct: 135 KWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIGTQEFVLHTPKITALKWWPGNLG 194 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 K S +AVV A + GK++G H F+V LR + H PLP IT+GDIG KM AYN +DNG Sbjct: 195 KSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLPGITIGDIGPKM---AYNIVDNG 251 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 FL F++ RIPR +LMR +KV +G Y+ K + Y MV+VR ++ + LS A+ Sbjct: 252 FLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAK-INYSAMVHVRSYMLTGQAIMLSYAL 310 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 IATRYSAVRRQ E +V++Y+TQQ+RLFP +A AYAF+F G LY V + Sbjct: 311 NIATRYSAVRRQGQIDKNEPEVKVLEYQTQQHRLFPFIARAYAFQFAGAETVKLYERVLK 370 Query: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 + + + + + + HA T+GLKS+ T T +GIE+ R CGGHGY S + E++ V + Sbjct: 371 EMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMACGGHGYSMASYISEIYGVAIGG 430 Query: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 CTYEG+N+V+ LQ+AR+L+K+ A + SGK + +G L RS D + Sbjct: 431 CTYEGENMVMLLQLARYLVKSAALVKSGKA-----SQLGPLVAYLGARSEPTSLIDRVPN 485 Query: 481 DVVLE---AFEARALRMAVTCAKN----LSKFENQEQGFQELLADLVEAAIAHCQLIVVS 533 + E F+ A R + A + E +E + + +L A+ H +L +V Sbjct: 486 GGITEYIKTFQHIAKRQTLKAANKFFGLMENGEKREIAWNKSSVELNRASRLHTRLFIVE 545 Query: 534 KFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLY 593 F A+ +IG +K+ L++L +++ Y L L ++ Q DQL Sbjct: 546 AF-ARRVNEIGDITIKEALSDLLHLHVNYELLDVATYALEDGFMSSTQLDYVRDQLYFYL 604 Query: 594 TQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRP 653 ++RPNAV+L+D++ ++D L SVLGR DG+VY LF+ A + PLN + V YL+P Sbjct: 605 QKIRPNAVSLLDSWEFSDRELRSVLGRRDGHVYENLFKWAKESPLNKTDVLPSVDTYLKP 664 Query: 654 VLQQ 657 ++++ Sbjct: 665 MMEK 668 >5K3J-A nrPDB Length = 674 Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust. Identities = 252/665 (37%), Positives = 377/665 (56%), Gaps = 34/665 (5%) Query: 7 LADERNKAEFDVEDMKIVWAGS----RHAFEVSDRIARLVASDPVFEKSNRARLSRKELF 62 L +ER A FD + M V GS R E++D ++++ + + L+R+E Sbjct: 14 LLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKI---PELADIKPYPFLTREEKV 70 Query: 63 KSTLRKCAHAFKRIIEL--RLNEEEAGRL-RHFIDQPAY-VDLHWGMFVPAIKGQGTEEQ 118 RK + K + +L R NEEE+ L R I + LH +F+P ++ Q ++EQ Sbjct: 71 TEGTRKISILTKYLNQLIDRDNEEESLHLHREVIGYEGHPFALHDALFIPTLQSQASDEQ 130 Query: 119 QKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGG 178 Q+KWL A + +IIGCYAQTELGHGSN++ LETTA +D + EFV+HTPT TA KWWPG Sbjct: 131 QEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALKWWPGA 190 Query: 179 LGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMD 238 LGK +A+V A LI +YG H F+VQLR + H PL +TVGDIG KM +N+ D Sbjct: 191 LGKSCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMN---FNAAD 247 Query: 239 NGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSR 298 NG+L +++R+PR +LMR KV +G YV K + Y MV +R + + L+ Sbjct: 248 NGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAK-IGYSGMVKIRSQMAMEQGLFLAH 306 Query: 299 AVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDV 358 A+ IA RYSAVRRQ + +E +V+DY+TQQ+RLFP LA AYAF F G LY+ + Sbjct: 307 ALTIAARYSAVRRQGHLDDKQVEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQL 366 Query: 359 TERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYV 418 + + + + + + HA T+GLKS+ T +GIE+ R CGGHGY S + ++ + + Sbjct: 367 LKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIEQARMACGGHGYSMASYISVVYGIAI 426 Query: 419 PACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWL 478 CTY G+N+V+ LQ+AR+L+K+V + +GK +G A L +S D Sbjct: 427 GGCTYAGENMVMLLQLARYLVKSVELIKAGK-----AKKLGPVASYLADKS---DETDLT 478 Query: 479 NPDVVLEAFEARALRMAVTCAKNLSKF----ENQEQGFQELLADLVEAAIAHCQLIVVSK 534 + + ++ FE A R A + K E++E + + +L A+ H +L ++ Sbjct: 479 SLNGYVKMFENMARRQAWKATEKFLKLMESGESREVAWNKSAVELTRASRLHTRLFIIEA 538 Query: 535 FIAKLE--QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSL 592 F+ ++ +DI K V L +L Y L + + +F+S Q DQL Sbjct: 539 FMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALEFMSFT-----QLDYVRDQLYLY 593 Query: 593 YTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLR 652 ++RPNAV+LVD+F +D L SVLGR DG+VY LF+ A PLN++ V ++YL+ Sbjct: 594 LEKIRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPLNNADVLPSVEKYLK 653 Query: 653 PVLQQ 657 P++++ Sbjct: 654 PMMEK 658 >5Y9D-A nrPDB Length = 709 Score = 387 bits (995), Expect = e-108, Method: Compositional matrix adjust. Identities = 233/672 (34%), Positives = 361/672 (53%), Gaps = 32/672 (4%) Query: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 +A ER K +F V D+ G ++ ++I + DPV + + ++ K T+ Sbjct: 33 MAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTM 92 Query: 67 RKCAHAFKRIIE--LRLNEEEAGRLRHFIDQPAY--VDLHWGMFVPAIKGQGTEEQQKKW 122 + A ++ +L+ A +L +D + +H +F+ +I+G GT EQ K W Sbjct: 93 ERVAALSPYLVTDTEKLSLWRA-QLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYW 151 Query: 123 L---SLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGL 179 + ++A K Q GC+A TELGHGSN++GLETTAT+D +D+F+I+TP A+KWW GG Sbjct: 152 VKKGAVAVK-QFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGA 210 Query: 180 GKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDN 239 STH V +A+LI +GKDYG F+V LR++ DHS +++GDIG KMG + +DN Sbjct: 211 AHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGR---DGVDN 267 Query: 240 GFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRA 299 G++ F +VRIPR MLMR +KV+ G V QL YG ++ R +++AD+ + R Sbjct: 268 GWIQFTNVRIPRQNMLMRYAKVSDTG-VVTKPALDQLTYGALIRGRVSMIADSFHVSKRF 326 Query: 300 VCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVT 359 + IA RY+ VRRQFG ET++IDY Q RL PLLA YA + + + + + T Sbjct: 327 LTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETT 386 Query: 360 ERLAASD-------------FATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLW 406 +R+ A + E A +AG+K+ TT A I+ECR+ CGGHGY Sbjct: 387 DRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSG 446 Query: 407 CSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQ 466 +G + +A +V CT+EGDN VL L + R L+++ Q+ +GK + Y+G + + Q Sbjct: 447 YNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQ 506 Query: 467 CRSGVQKAEDWLNPDVVLEAFEARALRMAVTCA---KNLSKFENQEQGFQELLADLVEAA 523 G + E L+P+ ++EAF + + + L K N +Q F+EL + A Sbjct: 507 NGQGTPR-EQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCA 565 Query: 524 IAHCQLIVVSKFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQAS 583 H + ++S F A++ +K L L ++AL+ + + G FL N +TP Sbjct: 566 RIHTRQHLISSFYARIA--TAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDID 623 Query: 584 LANDQLRSLYTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVV 643 L N + L VR + L DAF +D ++N+ +G YDGNVY K F + + + Sbjct: 624 LINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPR 683 Query: 644 PDGYQEYLRPVL 655 P Y+ L+P L Sbjct: 684 PPYYESTLKPFL 695 >5YS9-A nrPDB Length = 708 Score = 371 bits (953), Expect = e-103, Method: Compositional matrix adjust. Identities = 238/676 (35%), Positives = 353/676 (52%), Gaps = 44/676 (6%) Query: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 LA ER K +F ++DM G + +R+ + DPV S + +++L ++ Sbjct: 27 LAGERAKVKFPIKDMTEFLHGGEENVTMIERLMTELERDPVLNVSGDYDMPKEQLRET-- 84 Query: 67 RKCAHAFKRIIEL-----RLNEEEA---GRLRHFIDQPAYVDL--HWGMFVPAIKGQGTE 116 A RI L + E+EA +L +D + L H G+F+ AI+G GT+ Sbjct: 85 -----AVARIAALSGHWKKDTEKEALLRSQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTK 139 Query: 117 EQQKKWL--SLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKW 174 EQ W+ A+ GC+A TELGHGSNV GLETTAT+ TDEF+I+TP A+KW Sbjct: 140 EQYDYWVRKGAADVKGFYGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKW 199 Query: 175 WPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAY 234 W GG +TH +ARL+ +GKDYG+ F+VQLR + HS +P I +GDIG KMG Sbjct: 200 WIGGAAHSATHTACFARLLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGR--- 256 Query: 235 NSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASN 294 +++DNG++ F +VRIPR MLM+ +KV+ G+ V QL YG ++ R T++AD+ Sbjct: 257 DAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGK-VSQPPLAQLTYGALIGGRVTMIADSFF 315 Query: 295 ALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWL 354 R + IA RY+ VRRQFG G ET++IDY Q RL PLLA YA + + + Sbjct: 316 VSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQ 375 Query: 355 YTDVTERLAASD----------FATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGY 404 Y T+ L D L E A +AGLK+ TT A+ I++CR+ CGGHGY Sbjct: 376 YDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGY 435 Query: 405 LWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTT-AYMGRAAH 463 +G + +A +V CT+EGDN VL L + R L+++ GK P+G++ Y+ Sbjct: 436 SGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGLIQSCLGHRKGK-PLGSSVGYLANKGL 494 Query: 464 LLQCRSGVQKAEDWLNPDVVLEAFEA---RALRMAVTCAKNLSKFE-NQEQGFQELLADL 519 SG D +P V++EA+E A++ A L+K + +Q F+EL Sbjct: 495 EQATLSG----RDLKDPKVLIEAWEKVANGAIQRATDKFVELTKGGLSPDQAFEELSQQR 550 Query: 520 VEAAIAHCQLIVVSKFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITP 579 + A H + +V+ F ++ VK L NL ++ L+ + + G FL + P Sbjct: 551 FQCAKIHTRKHLVTAFYERINASAKAD-VKPYLINLANLFTLWSIEEDSGLFLREGFLQP 609 Query: 580 KQASLANDQLRSLYTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLN 639 K + + +VR DAF +D ++N+ +G YDG+VY F + + Sbjct: 610 KDIDQVTELVNHYCKEVRDQVAGYTDAFGLSDWFINAPIGNYDGDVYKHYFAKVNQQNPA 669 Query: 640 DSVVPDGYQEYLRPVL 655 + P Y+ LRP L Sbjct: 670 QNPRPPYYESTLRPFL 685 >3MDE-A nrPDB Length = 385 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 61/211 (28%), Positives = 96/211 (45%), Gaps = 34/211 (16%) Query: 107 VPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHT 166 VP I G G +QQKK+L + ++ Y TE G GS+V G++T A + K DE++I+ Sbjct: 96 VPLIIG-GNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN- 151 Query: 167 PTQTASKWWPGGLGKVSTHAVVYARLITNGK---DYGIHGFIVQLRSLEDHSPLPNITVG 223 K W GK + + ++ AR + K GFIV+ + P + +G Sbjct: 152 ----GQKMWITNGGKANWYFLL-ARSDPDPKAPASKAFTGFIVE-------ADTPGVQIG 199 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 MG D ++F+ VR+P++ +L T EG ++ GT Sbjct: 200 RKEINMGQ---RCSDTRGIVFEDVRVPKENVL------TGEGAGF------KIAMGTFDK 244 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFG 314 R + A A RA+ AT+Y+ R+ FG Sbjct: 245 TRPPVAAGAVGLAQRALDEATKYALERKTFG 275 >1UKW-A nrPDB Length = 379 Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 72/326 (22%), Positives = 138/326 (42%), Gaps = 49/326 (15%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTEEQ++++L + + +A +E G+GS+ L+T A + D +V++ +K Sbjct: 101 GTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAI--RQGDHYVLN-----GTK 153 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W G+ + VV+A + + G+ +V+ + P I KMG A Sbjct: 154 MWISNGGE-AEWVVVFATVNPELRHKGVVALVVERGT-------PGFKAIKIHGKMGQRA 205 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 + + L+F+ V++P + +++ EGE ++ T+ R + A + Sbjct: 206 SGTYE---LVFEDVKVPVE------NRLGEEGEGF------KIAMQTLNKTRIPVAAGSV 250 Query: 294 NALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKW 353 RA+ A +Y+ R FG + +++ Q +L +L R + W Sbjct: 251 GVARRALDEARKYAKEREAFG-------EPIANFQAIQFKLVDMLIGIETARMYTYYAAW 303 Query: 354 LYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPEL 413 L LP AHA +A K+ + + + ++ GG+GY+ + +L Sbjct: 304 LADQ-----------GLPHAHA-SAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKL 351 Query: 414 FAVYVPACTYEGDNVVLQLQVARFLM 439 YEG N + +L +AR ++ Sbjct: 352 LRDVKLNQIYEGTNEIQRLIIARHIL 377 >3SF6-A nrPDB Length = 403 Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 65/225 (28%), Positives = 95/225 (42%), Gaps = 36/225 (16%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 + V + + + AI G++EQ+ +WL IGC+ TE HGS+ G+ T AT Sbjct: 110 SLVSVQGSLAMYAIHAFGSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATR- 168 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 D++++ T +K W G V+ AVV+AR D GI GF+V + Sbjct: 169 -SGDDWIL-----TGTKMWITN-GSVADVAVVWAR-----TDEGIRGFVVP-------TD 209 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P T I +KM A + + L+ D VR+P RL T G P + Sbjct: 210 TPGFTANTIKSKMSLRASVTSE---LVLDGVRLPDSA---RLPGATSLG--APLRCLNEA 261 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIE 321 +G IV A A + A Y+ R QF GG + Sbjct: 262 RFG--------IVFGALGAARDCLETALAYACSREQFDRPIGGFQ 298 >2VIG-A nrPDB Length = 391 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 113/261 (43%), Gaps = 39/261 (14%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G++EQ++ W++ IGC+A +E G+GS+ TTA + D +V++ + Sbjct: 103 GSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAE--GDSWVLNGTKAWITN 160 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W ++ AVV+A ++ I F+V + P P +T+G K+G Sbjct: 161 AWE------ASAAVVFASTDRALQNKSISAFLVPM-------PTPGLTLGKKEDKLGIRG 207 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 ++ + L+F+ RIP+D +L GE + ++ T+ R I + A Sbjct: 208 SSTAN---LIFEDCRIPKDSIL---------GE---PGMGFKIAMQTLDMGRIGIASQAL 252 Query: 294 NALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLK- 352 A+ A Y+ R FGA + QVI +K L L SA + LK Sbjct: 253 GIAQTALDCAVNYAENRMAFGAPL--TKLQVIQFKLADMAL--ALESARLLTWRAAMLKD 308 Query: 353 ----WLYTDVTERLAASDFAT 369 ++ +LAAS+ AT Sbjct: 309 NKKPFIKEAAMAKLAASEAAT 329 >1JQI-A nrPDB Length = 388 Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 49/202 (24%), Positives = 93/202 (46%), Gaps = 30/202 (14%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G+ +Q+++W++ IGC+A +E G+GS+ TTA + D +V++ + Sbjct: 107 GSSQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAR--EEGDSWVLNGTKAWITN 164 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W ++ VV+A + ++ GI F+V + P P +T+G K+G A Sbjct: 165 SWE------ASATVVFASTDRSRQNKGISAFLVPM-------PTPGLTLGKKEDKLGIRA 211 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 ++ + L+F+ RIP++ +L GE + ++ T+ R I + A Sbjct: 212 SSTAN---LIFEDCRIPKENLL---------GE---PGMGFKIAMQTLDMGRIGIASQAL 256 Query: 294 NALSRAVCIATRYSAVRRQFGA 315 ++ A +Y+ R FGA Sbjct: 257 GIAQASLDCAVKYAENRHAFGA 278 >2A1T-A nrPDB Length = 421 Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 52/204 (25%), Positives = 91/204 (44%), Gaps = 33/204 (16%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G ++Q+KK+L + ++ Y TE G GS+V G++T A + K DE++I+ K Sbjct: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN-----GQK 189 Query: 174 WWPGGLGKVSTHAVVYARLITNGK---DYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMG 230 W GK + + ++ AR + K + GFIV+ + P I +G MG Sbjct: 190 MWITNGGKANWYFLL-ARSDPDPKAPANKAFTGFIVE-------ADTPGIQIGRKELNMG 241 Query: 231 NGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVA 290 D ++F+ V++P++ +L + ++ G R + A Sbjct: 242 Q---RCSDTRGIVFEDVKVPKENVL------------IGDGAGFKVAMGAFDKTRPVVAA 286 Query: 291 DASNALSRAVCIATRYSAVRRQFG 314 A RA+ AT+Y+ R+ FG Sbjct: 287 GAVGLAQRALDEATKYALERKTFG 310 >3PFD-A nrPDB Length = 393 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 88/361 (24%), Positives = 146/361 (40%), Gaps = 67/361 (18%) Query: 93 IDQPAYVDLHWGMFVPAIKG--------QGTEEQQKKWLSLANKMQIIGCYAQTELGHGS 144 I++ A VD + +PA+ +G+EE +K+ L + + YA +E GS Sbjct: 87 IEEVARVDCSASL-IPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASYALSEREAGS 145 Query: 145 NVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGF 204 + + T A D D+++++ SK W GK + + V+ G + GI F Sbjct: 146 DAASMRTRAVAD--GDDWILN-----GSKCWITNGGKSTWYTVMAVTDPDKGAN-GISAF 197 Query: 205 IVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTRE 264 +V H TVG K+G + + L F++ RIP D+++ Sbjct: 198 MV-------HKDDEGFTVGPKERKLGIKGSPTTE---LYFENCRIPGDRII--------- 238 Query: 265 GEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGIE 321 GE P K + T+ + R TI A A A+ A Y+ R+QFG + N G++ Sbjct: 239 GE--PGTGFKTAL-ATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQ 295 Query: 322 TQVID--YKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAG 379 + D K + RL A+A A R G D + A C A Sbjct: 296 FMLADMAMKIEAARLMVYSAAARAERGEG-----------------DLGFISAASKCFA- 337 Query: 380 LKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM 439 + T D ++ L GG+GY + + YEG N + ++ ++R L+ Sbjct: 338 -SDVAMEVTTDAVQ----LFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALL 392 Query: 440 K 440 + Sbjct: 393 R 393 >4L1F-A nrPDB Length = 383 Score = 52.4 bits (124), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 90/201 (44%), Gaps = 30/201 (14%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTEEQ++K+L+ + +G + TE G++ +TTA K D+++++ SK Sbjct: 102 GTEEQKQKYLAPIAEGTHVGAFGLTEPSAGTDASAQQTTAVL--KGDKYILN-----GSK 154 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 + GK + VV+A + +GI FI++ +P G I KMG Sbjct: 155 IFITN-GKEADTYVVFAMTDKSQGVHGISAFILE-------KGMPGFRFGKIEDKMGG-- 204 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 ++ L+F+ +P++ +L +EGE ++ T+ R + A A Sbjct: 205 -HTSITAELIFEDCEVPKENLL------GKEGEGF------KIAMETLDGGRIGVAAQAL 251 Query: 294 NALSRAVCIATRYSAVRRQFG 314 A+ A +YS R QFG Sbjct: 252 GIAEGALAAAVKYSKEREQFG 272 >4N5F-A nrPDB Length = 385 Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 83/343 (24%), Positives = 131/343 (38%), Gaps = 55/343 (16%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 + +H + I G GT Q+ +WL+ ++IG + TE GS L T A + Sbjct: 95 MSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVIGAFCLTEPHAGSEANNLRTRAEL--R 152 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 ++V++ Q + G+ + A+V+A GI F+V + P Sbjct: 153 DGQWVLNGAKQFVTN------GQRAGVAIVFAMTDPEAGKRGISAFLVP-------TDTP 199 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 VG KMG + D + F++ IP D +L GE + ++ Sbjct: 200 GFIVGKPEKKMG---IRASDTCPITFENCAIPEDNLL------GNRGEGL------KIAL 244 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQQNRLF 335 + R I A A A A RY+ R QFG A + I+ ++ D Q N Sbjct: 245 SNLEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAAR 304 Query: 336 PLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEEC 395 L+ A R G L L +L AS+ A C+ D I+ Sbjct: 305 LLVHHAAKLRTAG--LPCLSEASQAKLFASEMAE----RVCS------------DAIQ-- 344 Query: 396 RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 + GG+GYL + + YEG + V ++ +AR L Sbjct: 345 --IHGGYGYLVDYEVERHYRDARITQIYEGTSEVQRMVIARQL 385 >2IX5-A nrPDB Length = 436 Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 136/347 (39%), Gaps = 69/347 (19%) Query: 98 YVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDP 157 ++ +H + + I G+E Q++K+L ++ + C+A TE +GS+ GL TTAT Sbjct: 135 FILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTAT--- 191 Query: 158 KTDEFVIHTPTQTASKWWPGGLGKVSTHA---VVYARLITNGKDYGIHGFIVQLRSLEDH 214 V K W G ST A +++AR T + I+GFIV+ + Sbjct: 192 ----KVEGGWKINGQKRWIGN----STFADLLIIFARNTTTNQ---INGFIVKKDA---- 236 Query: 215 SPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPK 274 P + I K+G + NG ++ +V +P + L ++ D K Sbjct: 237 ---PGLKATKIPNKIG---LRMVQNGDILLQNVFVPDEDRLPGVNSF--------QDTSK 282 Query: 275 QLVYGTMVYVRQTIVADASNALSRAVC-IATRYSAVRRQFGAHNGGIETQVIDYKTQQNR 333 L V + +VA +S + + RY R+QFGA + ++ Q + Sbjct: 283 VLA------VSRVMVAWQPIGISMGIYDMCHRYLKERKQFGA-------PLAAFQLNQQK 329 Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 L +L + A +G L LY E T G SL + Sbjct: 330 LVQMLGNVQAMFLMGWRLCKLY----------------ETGQMTPGQASLGKAWISSKAR 373 Query: 394 EC----RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 E R+L GG+G L + + F P TYEG + L R Sbjct: 374 ETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 >6FAH-C nrPDB Length = 379 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 78/339 (23%), Positives = 141/339 (41%), Gaps = 73/339 (21%) Query: 114 GTEEQQKKWLS--LANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTA 171 GTEEQ +K+L + K ++ +A TE G GS+ G+ TTA ++ + +T Sbjct: 101 GTEEQIEKYLKPIITGKKKL--AFALTEPGAGSDAGGMSTTAV---DMGDYYLLNGRKTF 155 Query: 172 SKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGN 231 P + AV+YA+ + GI FIV L+S +++G KMG Sbjct: 156 ITMAP-----LCDDAVIYAKTDMSKGTRGISAFIVDLKS-------EGVSMGKNEHKMGL 203 Query: 232 GAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVAD 291 + D ++ + V++P++ RL +V + S+ K L G + Q+I Sbjct: 204 IGCATSD---IIMEDVKVPKEN---RLGEVNKG----FSNAMKTLDVGRLGVASQSI-GV 252 Query: 292 ASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWL 351 A AL A+ +Y+ R+QFG ++ D+ + + Sbjct: 253 AQGALDEAI----KYAKERKQFG-------KRIADF---------------------QAI 280 Query: 352 KWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGI---EECRKLC-------GG 401 ++ D+ +L A+ + A + K+ T A+ E C ++C GG Sbjct: 281 AFMIADMATKLEAAKL-LVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGG 339 Query: 402 HGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 +GY+ + ++ YEG + V Q+ ++ L+K Sbjct: 340 YGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLK 378 >3MPI-A nrPDB Length = 397 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 46/201 (22%), Positives = 90/201 (44%), Gaps = 30/201 (14%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G+E +KK++ + + +G + TE GS+V + +TA + K D ++++ SK Sbjct: 105 GSEALKKKYVPKLSSAEFLGGFGITEPDAGSDVMAMSSTA--EDKGDHWLLN-----GSK 157 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W + + YA G+ F+++ R+ P I ++ K+G+ A Sbjct: 158 TWISNAAQADV-LIYYAYTDKAAGSRGLSAFVIEPRN------FPGIKTSNL-EKLGSHA 209 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 + G L D+V++P++ +L + P D + +V+G++ + R + A Sbjct: 210 SPT---GELFLDNVKVPKENILGK-----------PGDGAR-IVFGSLNHTRLSAAAGGV 254 Query: 294 NALSRAVCIATRYSAVRRQFG 314 + A +Y RRQFG Sbjct: 255 GLAQACLDAAIKYCNERRQFG 275 >5LNX-A nrPDB Length = 379 Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 80/330 (24%), Positives = 134/330 (40%), Gaps = 57/330 (17%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G EEQ+ K++ +G +A TE GS+ L TTA K +++++ SK Sbjct: 100 GNEEQKMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAI--KKNGKYLLN-----GSK 152 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 + G + + +A + +GI FIV+ + P TVG K+G Sbjct: 153 IFITNGGAADIY-ITFALTAPDQGRHGISAFIVEKNT-------PGFTVGKKERKLGLYG 204 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 N+ + L+FD+ +P +L +EG+ + + R I A A Sbjct: 205 SNTTE---LIFDNAEVPEANLL------GKEGDGF------HIAMANLNVGRIGIAAQAL 249 Query: 294 NALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEW 350 A+ A Y+ R QFG A N GI ++ D T+ A A R Sbjct: 250 GIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATR----------AEAAR----H 295 Query: 351 LKWLYTDVTER-LAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSG 409 L + D+ R L A++ + A A +K A D ++ + GG+GY+ Sbjct: 296 LVYHAADLHNRGLNCGKEASMAKQFASDAAVK-----AALDAVQ----IYGGYGYMKDYP 346 Query: 410 LPELFAVYVPACTYEGDNVVLQLQVARFLM 439 + L YEG N + +L ++++L+ Sbjct: 347 VERLLRDAKVTQIYEGTNEIQRLIISKYLL 376 >3SWO-A nrPDB Length = 399 Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 23/159 (14%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 ++V + + + +I G+EEQ+ +WL IGC+ TE GSN G+ T A D Sbjct: 105 SFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRD 164 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 +++++ +K W G ++ A V+A+ D GI GF+V + Sbjct: 165 --GSDWILN-----GTKMWITN-GNLADVATVWAQ-----TDDGIRGFLVP-------TD 204 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQML 255 P T +I K+ A + + L+ D+VR+P L Sbjct: 205 TPGFTANEIHRKLSLRASVTSE---LVLDNVRLPASAQL 240 >3OWA-A nrPDB Length = 597 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 78/348 (22%), Positives = 152/348 (43%), Gaps = 53/348 (15%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G EEQ+KK+L L + + YA TE G GS+ G +TTA + + +V++ Q Sbjct: 130 GNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQ---- 185 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W + +VYA++ +G+ + FIV+ +D++ ++ KMG Sbjct: 186 WITN--SAFADVFIVYAKI--DGEHF--SAFIVE----KDYA---GVSTSPEEKKMGIKC 232 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 ++ L+ + +P++ +L + K G + ++ L G R + Sbjct: 233 SSTRT---LILEDALVPKENLLGEIGK----GHIIAFNI---LNIG-----RYKLGVGTV 277 Query: 294 NALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYA-----FRFVG 348 + RAV I+ +Y+ R+QF + + + Q +L + A YA +R VG Sbjct: 278 GSAKRAVEISAQYANQRQQF-------KQPIARFPLIQEKLANMAAKTYAAESSVYRTVG 330 Query: 349 EWLKWLYTDVTERL--AASDFATLPEAHACTAGLKSLTTTATAD-GIEECRKLCGGHGYL 405 + + T E + + A++ E +A L + + D ++E ++ GG+G++ Sbjct: 331 LFESRMSTLSEEEVKDGKAVAASIAE-YAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFM 389 Query: 406 WCSGLPELFAVYVPACTYEGDNVVLQLQV-ARFLMKTVAQLGSGKVPV 452 + ++ +EG N + +L V FL K + G++P+ Sbjct: 390 AEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRKAM----KGELPL 433 >3B96-A nrPDB Length = 587 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 86/371 (23%), Positives = 151/371 (40%), Gaps = 65/371 (17%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GT+ Q++K+L + + + TE GS+ + T+A P + ++ SK Sbjct: 125 GTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLN-----GSK 179 Query: 174 WW--PGGLGKVSTHAVVYARLITNGKDYG-----IHGFIVQLRSLEDHSPLPNITVGDIG 226 W GGL + T V+A+ G I F+V+ IT G Sbjct: 180 LWISNGGLADIFT---VFAKTPVTDPATGAVKEKITAFVVE-------RGFGGITHGPPE 229 Query: 227 TKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQ 286 KMG A N+ + + FD VR+P + +L + + ++ ++ R Sbjct: 230 KKMGIKASNTAE---VFFDGVRVPSENVLGEVGSGFKVAMHILNN------------GRF 274 Query: 287 TIVADASNALSRAVCIATRYSAVRRQFGA--HNGGIETQVIDYKTQQNRLFPLLASAYAF 344 + A + + + A ++ R QFG HN G+ I K LA Sbjct: 275 GMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGL----IQEK---------LARMVML 321 Query: 345 RFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGY 404 ++V E + ++ + ++ A+DF + A + K + A +EC ++ GG G+ Sbjct: 322 QYVTESMAYMVSANMDQ-GATDF----QIEAAIS--KIFGSEAAWKVTDECIQIMGGMGF 374 Query: 405 LWCSGLPELFAVYVPACTYEGDNVVLQLQVA-RFLM---KTVAQLGSG-KVPVGTTA-YM 458 + G+ + +EG N +L+L VA + M K ++ LGS K P G + Sbjct: 375 MKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLL 434 Query: 459 GRAAHLLQCRS 469 G A L+ R+ Sbjct: 435 GEAGKQLRRRA 445 >6ES9-A nrPDB Length = 551 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 60/208 (28%), Positives = 82/208 (39%), Gaps = 34/208 (16%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTE Q+ KWL +I+ TE GS++ L T A D +++V+ T +K Sbjct: 264 GTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRD--GEDWVV-----TGNK 316 Query: 174 WWPGGLGKVSTHA------VVYARLITNGKDY-GIHGFIVQLRSLEDHSPLPNITVGDIG 226 W THA + AR D+ G+ F+ + D P P T G G Sbjct: 317 TW-------ITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFP--TPGMTG 367 Query: 227 TKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQ 286 ++ Y M L FD RI + +L GE P KQL+ T R Sbjct: 368 GEIEVLGYRGMKEYELGFDGFRIKGENLL--------GGE--PGRGFKQLME-TFESARI 416 Query: 287 TIVADASNALSRAVCIATRYSAVRRQFG 314 A A A I RY+ R+QFG Sbjct: 417 QTAARAVGVAQSAAEIGMRYAVDRKQFG 444 >5IDU-A nrPDB Length = 410 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 82/343 (23%), Positives = 133/343 (38%), Gaps = 57/343 (16%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 G+ AI GT EQ+ ++L +K + I +A +E GS+V + A + D +V Sbjct: 113 GLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQAR--AEGDCYV 170 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 I K W G ++ VV+AR GI FIV + P + + Sbjct: 171 ID-----GDKTWISN-GGIADFYVVFARTGEAPGARGISAFIVD-------ADTPGLQIA 217 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 + ++ A + + L FD R+PR QML P + K + T+ Sbjct: 218 E---RIDVIAPHPLAR--LHFDSARVPRSQML-----------GAPGEGFK-IAMRTLDV 260 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL---LAS 340 R ++ A + RA+ +A R+ FG G D++ Q +L + + S Sbjct: 261 FRTSVAAASLGFARRALQEGLARAASRKMFGQTLG-------DFQLTQTKLAQMALTIDS 313 Query: 341 AYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCG 400 + + WL+ +VT A + + HA + I+ +L G Sbjct: 314 SALLVYRAAWLRDQGENVTRE------AAMAKWHASEGAQQV---------IDAAVQLWG 358 Query: 401 GHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVA 443 G G + + L+ YEG V QL V R L+K A Sbjct: 359 GMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHA 401 >1SIR-A nrPDB Length = 394 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/226 (23%), Positives = 93/226 (41%), Gaps = 40/226 (17%) Query: 110 IKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQ 169 I G+EEQ++K+L K +++GC+ TE GS+ +ET A ++ + ++ Sbjct: 108 IYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLN---- 163 Query: 170 TASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQ--LRSLEDHSPLPNITVGDIGT 227 +K W ++ VV+AR +D I GF+++ +R L P I Sbjct: 164 -GTKTWITN-SPMADLFVVWARC----EDGCIRGFLLEKGMRGLS----APRI------- 206 Query: 228 KMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQT 287 G + + G ++ D V +P + +L P +G + R Sbjct: 207 -QGKFSLRASATGMIIMDGVEVPEENVL-------------PGASSLGGPFGCLNNARYG 252 Query: 288 IVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQ 330 I A + A +Y+ R QFG A N I+ ++ D T+ Sbjct: 253 IAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTE 298 >3NF4-A nrPDB Length = 387 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 36/209 (17%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTEEQ+K+WL + IG Y+ +E GS+ L AT P +VI+ SK Sbjct: 112 GTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAAT--PTDGGYVIN-----GSK 164 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W GK + ++AR T G+ F+V + P ++ G KMG Sbjct: 165 SWITHGGKADFY-TLFAR--TGEGSRGVSCFLVP-------ADQPGLSFGKPEEKMG--- 211 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 +++ +D+ RI D+ ++ EG+ + Q+ + + R I A A+ Sbjct: 212 LHAVPTTSAFYDNARIDADR------RIGEEGQGL------QIAFSALDSGRLGIAAVAT 259 Query: 294 N----ALSRAVCIATRYSAVRRQFGAHNG 318 AL AV A +A R+ H G Sbjct: 260 GLAQAALDEAVAYANERTAFGRKIIDHQG 288 >4U83-A nrPDB Length = 382 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 78/328 (23%), Positives = 127/328 (38%), Gaps = 55/328 (16%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTE+Q++++L + IG +A TE GS+ L+T A D D +VI Q + Sbjct: 107 GTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLD--GDHYVIDGSKQFITS 164 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 GK +V+A GI FIV + P V + K+G Sbjct: 165 ------GKNGNVVIVFAVTDPAAGKKGISAFIVP-------TDTPGYEVMSVEHKLGQ-- 209 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 +S D L F ++R+P + +++ EGE ++ + R I A A Sbjct: 210 -HSSDTCALGFTNMRVPVE------NRLGAEGEGY------KIALANLEGGRIGIAAQAV 256 Query: 294 NALSRAVCIATRYSAVRRQFGA---HNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEW 350 A A Y+ R FG + + ++ D T+ ++ A A R G+ Sbjct: 257 GMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAAALREAGK- 315 Query: 351 LKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGL 410 L +L AS+ A C+A + ++ GG+GYL + Sbjct: 316 -PCLTEASMAKLVASEMAE----QVCSAAI----------------QIHGGYGYLADYPV 354 Query: 411 PELFAVYVPACTYEGDNVVLQLQVARFL 438 ++ YEG + V +L +AR L Sbjct: 355 ERIYRDVRVCQIYEGTSDVQRLVIARGL 382 >1RX0-A nrPDB Length = 393 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 83/360 (23%), Positives = 139/360 (38%), Gaps = 82/360 (22%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 AY+ +H M I G EEQ+ K+ M+ Y TE G GS+ L T+A Sbjct: 99 AYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSA--K 155 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 + D ++++ SK + G G+ + VV R G GI +V+ Sbjct: 156 KQGDHYILN-----GSKAFISGAGESDIY-VVMCRTGGPGPK-GISCIVVE-------KG 201 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P ++ G K+G +NS ++F+ +P +++ EG+ Sbjct: 202 TPGLSFGKKEKKVG---WNSQPTRAVIFEDCAVP------VANRIGSEGQ---------- 242 Query: 277 VYGTMVYVR-----QTIVADASNALSRAVCIATR-YSAVRRQFGAHNGGIETQVIDYKTQ 330 G ++ VR + +A S + A I TR + VR+QFG Sbjct: 243 --GFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGE--------------- 285 Query: 331 QNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLK---SLTTTA 387 PL ++ Y L++ D+ RL A+ A A K +L + A Sbjct: 286 -----PLASNQY--------LQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMA 332 Query: 388 TADGIEECRKLC-------GGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 +EC +C GG+GYL + + EG N V+++ ++R L++ Sbjct: 333 KLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 392 >2PG0-A nrPDB Length = 385 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/58 (39%), Positives = 32/58 (55%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 + LH + P I GTEEQ++KWL ++I A TE G GS++ + TTA D Sbjct: 91 IGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIAMTEPGAGSDLANISTTAVKD 148 >5OL2-C nrPDB Length = 378 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/202 (25%), Positives = 85/202 (42%), Gaps = 32/202 (15%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G EEQ++K+L + +G + TE G++ G +TTA D DE++++ + Sbjct: 101 GNEEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLD--GDEYILNGSKIFITN 158 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMG-NG 232 G + VV A + + GI FIV+ + P + G KMG G Sbjct: 159 AIAGDI------YVVMAMTDKSKGNKGISAFIVEKGT-------PGFSFGVKEKKMGIRG 205 Query: 233 AYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADA 292 + S L+F+ RIP++ +L +EG+ ++ T+ R I A A Sbjct: 206 SATSE----LIFEDCRIPKENLL------GKEGQGF------KIAMSTLDGGRIGIAAQA 249 Query: 293 SNALSRAVCIATRYSAVRRQFG 314 A+ +Y R QFG Sbjct: 250 LGLAQGALDETVKYVKERVQFG 271 >2Z1Q-A nrPDB Length = 577 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 46/201 (22%), Positives = 88/201 (43%), Gaps = 32/201 (15%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTEEQ++K+L + I Y TE G GS+ +T AT ++++ Q S Sbjct: 125 GTEEQKRKYLPKLASGEWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISN 184 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 G + T V+A++ +G+ + F+V+ + P ++ G KMG A Sbjct: 185 ---AGFAHLFT---VFAKV--DGEHF--TAFLVERDT-------PGLSFGPEEKKMGIKA 227 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 ++ ++ + V++P + +L + K ++ + + R + A A Sbjct: 228 SSTRQ---VILEDVKVPVENVLGEIGK------------GHKIAFNVLNVGRYKLGAGAV 272 Query: 294 NALSRAVCIATRYSAVRRQFG 314 RA+ ++ +Y+ R QFG Sbjct: 273 GGAKRALELSAQYATQRVQFG 293 >4IRN-A nrPDB Length = 416 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 67/326 (20%), Positives = 132/326 (40%), Gaps = 51/326 (15%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTEEQ++K+L L + I +A TE GS++ L+TTA D D+++++ + Sbjct: 139 GTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKD--GDKYILNGYKHYVTN 196 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 G ++ +++A + + G+ F+++ P + + +KMG Sbjct: 197 ------GTIADLFIIFATIDPSLGKEGLTTFMIE-------KDTPGLILSKPISKMG--- 240 Query: 234 YNSMDNGFLMFDHVRIPRDQML-MRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADA 292 +P ++ +S R GE + +M + R I+A A Sbjct: 241 ----------MRTAEVPELRLENCEVSAANRLGE---EGTGLAIFNHSMEWERGFILAAA 287 Query: 293 SNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLK 352 + R + + RY+ +QFG G + Q++ K + +L A AY ++ + Sbjct: 288 VGTMERLLEQSIRYARSHKQFGQAIG--KFQLVANKLVEMKLRLENAKAYLYK-----VA 340 Query: 353 WLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPE 412 W+ + L + A L + A E ++ G +GYL + L Sbjct: 341 WMKENKQMALLEASMANL------------YISEAWVQSCLEAIEIHGAYGYLTNTELER 388 Query: 413 LFAVYVPACTYEGDNVVLQLQVARFL 438 + + Y G + + ++ +A+FL Sbjct: 389 ELRDAIASKFYSGTSEIQRVVIAKFL 414 >5JSC-A nrPDB Length = 410 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 79/340 (23%), Positives = 128/340 (37%), Gaps = 57/340 (16%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 G+ AI GT EQ+ ++L I +A +E GS+V + +A D D +V Sbjct: 113 GLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSARED--GDAYV 170 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 + K W G ++ VV+AR GI F+V + P + Sbjct: 171 LD-----GDKTWISN-GGIADFYVVFARTGEAPGARGISAFVVD-------ADTPGL--- 214 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 +I ++ A + + L F R+PR QML P + K L T+ Sbjct: 215 EIAERIDVIAPHPLAR--LHFAGARVPRSQML-----------GAPGEGFK-LAMRTLDI 260 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL---LAS 340 R ++ A + A+ +A R+ FG G D++ Q +L + + S Sbjct: 261 FRTSVAAASLGFARHAMAEGVARAASRKMFGQTLG-------DFQLTQAKLAQMALTIDS 313 Query: 341 AYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCG 400 + + WL+ +VT A + + HA + I+ +L G Sbjct: 314 SALLVYRAAWLRDQGENVTRE------AAMAKWHASEGAQQV---------IDAAVQLYG 358 Query: 401 GHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 G G + + L+ YEG V QL V R L+K Sbjct: 359 GMGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGRDLLK 398 >4HR3-A nrPDB Length = 415 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 20/146 (13%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G++EQ++ WL + I + TE S+ AT + DE VI+ K Sbjct: 125 GSQEQKEVWLEPLLEGDIRSAFCMTEPDVASS-DATNMAATAVVEGDEVVIN-----GRK 178 Query: 174 WWPGGLGKVSTHAVVYARLI-TNGKDYGIHGFIVQLRSLEDHSPL--PNITVGDIGTKMG 230 WW G+G +++ L N Y H ++ P+ P ITV + MG Sbjct: 179 WWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVL--------VPMDTPGITVERMLPTMG 230 Query: 231 NGAYNSMD-NGFLMFDHVRIPRDQML 255 Y+ +G + FD+VR+P D + Sbjct: 231 --FYDEPGGHGVVSFDNVRLPADAFI 254 >4W9U-A nrPDB Length = 395 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 20/150 (13%) Query: 110 IKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQ 169 I G++EQ+KK+L ++IGC+ TE GS+ G++T A E + Sbjct: 112 IYAYGSDEQRKKYLPGLVSGELIGCFGLTEPDAGSDPAGMKTRA-------EKIDGGYRL 164 Query: 170 TASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKM 229 + SK W ++ VV+A+ + D I GFI++ + ++ IG K+ Sbjct: 165 SGSKMWISN-SPIADVFVVWAK--SAAHDNAIRGFILE-------KGMKGLSAPKIGGKL 214 Query: 230 GNGAYNSMDNGFLMFDHVRIPRDQMLMRLS 259 + + G ++ D V + D +L +S Sbjct: 215 ---SLRASITGEIVMDGVEVSEDAILPNVS 241 >3GNC-A nrPDB Length = 399 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 53/220 (24%), Positives = 90/220 (40%), Gaps = 35/220 (15%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G++ Q++K+L + IGC+ TE HGS+ + T A P + SK Sbjct: 119 GSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGGYSL-------SGSK 171 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W ++ VV+A+L +G+D I GFI++ +P + VG Sbjct: 172 MWITN-SPIADVFVVWAKLDEDGRDE-IRGFILEKGCKGLSAPAIHGKVG---------- 219 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADAS 293 + G ++ D +P + +L + +G P + + R I A Sbjct: 220 LRASITGEIVLDEAFVPEENILPHV-----KGLRGP--------FTCLNSARYGIAWGAL 266 Query: 294 NALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQ 330 A IA +Y R+QFG A N I+ ++ D +T+ Sbjct: 267 GAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTE 306 >4M9A-A nrPDB Length = 385 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 35/157 (22%), Positives = 65/157 (41%), Gaps = 18/157 (11%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 V +H + + GT EQ+++WL + +G ++ TE GS L T A + Sbjct: 95 VSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTVGAFSLTEPHAGSEAHNLRTRAEL--R 152 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 +++++ Q + GL A+V+A + G+ F+V + P Sbjct: 153 DGKWILNGSKQFVTNGARAGL------AIVFAMTDPDEGKRGLSAFVVP-------TDTP 199 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQML 255 VG KMG + D + ++ IP++ +L Sbjct: 200 GFIVGKPEKKMG---IRASDTCPITLENCAIPQENLL 233 >4O5M-A nrPDB Length = 390 Score = 37.0 bits (84), Expect = 0.026, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 18/154 (11%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H + V I G+ EQ+ K+L + +G A +E G GS+V ++ A + + D Sbjct: 98 HSNLCVNQITRNGSPEQRAKYLPKLISGEHVGALAMSEPGAGSDVVSMKLAA--EKRGDR 155 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 +V++ +K W G + VVYA+ + GI FI++ + + S + Sbjct: 156 YVLN-----GNKMWITN-GPDADVLVVYAKTDLSAGPRGISAFIIE-KGFKGFSTAQKL- 207 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQML 255 K+G N+ + L+F+ +P + +L Sbjct: 208 -----DKLGMRGSNTCE---LVFEDCEVPAENLL 233 >4IV6-A nrPDB Length = 388 Score = 37.0 bits (84), Expect = 0.030, Method: Compositional matrix adjust. Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 7/62 (11%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 GTEEQ++K+L ++ A TE G GS++Q + T A D D++VI+ SK Sbjct: 103 GTEEQKQKYLPRMATGELRATMALTEPGGGSDLQAMRTVARRD--GDDYVIN-----GSK 155 Query: 174 WW 175 W Sbjct: 156 TW 157 >2WBI-A nrPDB Length = 428 Score = 35.4 bits (80), Expect = 0.081, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 8/68 (11%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELG-HGSNVQGLETTATFDPKTDEFVIHTPTQTAS 172 G+EEQ+K+WL + I C+ TE S+ +E + D D +VI+ Sbjct: 131 GSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRD--EDSYVIN-----GK 183 Query: 173 KWWPGGLG 180 KWW G G Sbjct: 184 KWWSSGAG 191 >2EBA-A nrPDB Length = 385 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 53/221 (23%), Positives = 94/221 (42%), Gaps = 40/221 (18%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQG-LETTATF 155 ++V + + + I G+EEQ++++L + +++GC+ TE GS+ G ++T A Sbjct: 91 SFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFGLTEPDGGSDPYGNMKTRARR 150 Query: 156 DPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYG--IHGFIVQLRSLED 213 + D +V++ +K W G ++ AV++A KD G + GF+V + Sbjct: 151 E--GDTWVLN-----GTKMWITN-GNLAHLAVIWA------KDEGGEVLGFLVPTDT--- 193 Query: 214 HSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVP 273 P ++ KM A + + L+ + VR+P +RL K G P Sbjct: 194 ----PGFQAREVKRKMSLRASVTSE---LVLEEVRVPES---LRLPKAL--GLKAPLSCL 241 Query: 274 KQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG 314 Q +G I A AL A ++ R FG Sbjct: 242 TQARFG--------IAWGAMGALEAVYEEAVAFAKSRSTFG 274 >5ZW7-A nrPDB Length = 402 Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust. Identities = 44/229 (19%), Positives = 97/229 (42%), Gaps = 39/229 (17%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G+ E + K+L ++I A TE GS++ ++ TA P ++++ + Sbjct: 104 GSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATA--QPCEGGYILNGKKIFITN 161 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTK--MGN 231 ++ ++YA+ + G+ F+++ + P + VG++ K + N Sbjct: 162 ------APIADVFIIYAKTNPDHGFLGVSAFLIEKGT-------PGLNVGEVIPKDCLSN 208 Query: 232 GAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVAD 291 ++ ++F+ + IP+ Q ++ EG + + +M++ + + A Sbjct: 209 CPWSE-----IVFNDIFIPQSQ------RIGMEG------AGGAIFHDSMIWEKGCLSAL 251 Query: 292 ASNALSRAVCIATRYSAVRRQFGAHNG---GIETQVIDYK--TQQNRLF 335 L+R + Y+ R+QFG G + ++ID K +Q RL Sbjct: 252 FVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLM 300 >3R7K-A nrPDB Length = 403 Score = 33.1 bits (74), Expect = 0.36, Method: Compositional matrix adjust. Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 25/155 (16%) Query: 104 GMFVPAIKGQGTEEQQKKWL--SLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 G+ +P I G++ ++++ +LA KM IG TE G GS+V L T A + D Sbjct: 117 GIALPHIAANGSDALIERYVRPTLAGKM--IGSLGVTEPGAGSDVANLRTRAVRE--GDT 172 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGF-IVQLRSLEDHSPLPNI 220 +V++ K + V A +T G G+ V L ++ +S P Sbjct: 173 YVVNGA-------------KTFITSGVRADFVTTAVRTGGPGYGGVSLLVIDKNS--PGF 217 Query: 221 TVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQML 255 V KMG + D L F VR+P D ++ Sbjct: 218 EVSRRLDKMG---WRCSDTAELSFVDVRVPADNLV 249 >1IVH-A nrPDB Length = 394 Score = 32.3 bits (72), Expect = 0.62, Method: Compositional matrix adjust. Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 20/156 (12%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H + + + G E Q++K+L + IG A +E GS+V ++ A + K + Sbjct: 100 HSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKA--EKKGNH 157 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYAR--LITNGKDYGIHGFIVQLRSLEDHSPLPN 219 ++++ +K+W G + +VYA+ L GI FIV+ +P Sbjct: 158 YILN-----GNKFWITN-GPDADVLIVYAKTDLAAVPASRGITAFIVE-------KGMPG 204 Query: 220 ITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQML 255 + K+G N+ + L+F+ +IP +L Sbjct: 205 FSTSKKLDKLGMRGSNTCE---LIFEDCKIPAANIL 237 >3U33-A nrPDB Length = 541 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 45/175 (25%), Positives = 65/175 (37%), Gaps = 17/175 (9%) Query: 296 LSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLY 355 + RA +A ++ R FG N I+ ++ + + L +A FR W + Sbjct: 310 MRRAFSLAIYHAHQRHVFG--NPLIQQPLMRHVLSRMALQLEGQTALLFRLARAWDR--R 365 Query: 356 TDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFA 415 D E L A F + C G+ + E ++ GG GY S LP L+ Sbjct: 366 ADAKEALWARLFTPAAKFVICKRGMPF---------VAEAMEVLGGIGYCEESELPRLYR 416 Query: 416 VYVPACTYEGDNVVLQLQVARFLMKTVA---QLGSGKVPV-GTTAYMGRAAHLLQ 466 +EG ++ L V R L K L V V G Y RA LQ Sbjct: 417 EMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLSEAFVEVKGQDRYFDRAVRRLQ 471 >1KYQ-A nrPDB Length = 274 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 25/36 (69%), Gaps = 2/36 (5%) Query: 571 FLSTNCITPKQASLANDQLRSLYTQVRPNAVALVDA 606 +STN ++P+ +L D++R+L+TQ+ +AL DA Sbjct: 163 LISTNGLSPRFGALVRDEIRNLFTQM--GDLALEDA 196 >5LON-B nrPDB Length = 188 Score = 30.0 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Query: 153 ATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAV--VYAR 191 A +DPK + + HTP T KW K+ V +Y R Sbjct: 19 ARYDPKIKQLLFHTPHATVYKWGDDNWNKLEYQGVLAIYLR 59 >5O9W-A nrPDB Length = 367 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 14/61 (22%) Query: 193 ITNGKDYGIHGFIVQLRSLE-----------DHSPLPN---ITVGDIGTKMGNGAYNSMD 238 +T+ D+G ++Q+ +E PLPN + VGDI M NG Y+S+D Sbjct: 238 LTSHSDFGGLTILLQINEVEGLQIKREGTWISVKPLPNAFVVNVGDILEIMTNGIYHSVD 297 Query: 239 N 239 + Sbjct: 298 H 298 >2DVL-A nrPDB Length = 372 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 39/203 (19%) Query: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASK 173 G+E Q++++L + + IG + TE GS+ + L A FV++ K Sbjct: 100 GSEAQKRRYLVPLARGEWIGAFCLTEPQAGSDAKSLRAEAR--RVKGGFVLN-----GVK 152 Query: 174 WWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGA 233 W G HA +Y ++ + GI F+V+ P ++ G KMG A Sbjct: 153 SWITSAG----HAHLY--VVMARTEKGISAFLVE-------KGTPGLSFGRPEEKMGLHA 199 Query: 234 YNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGT--MVYVRQTIVAD 291 ++ + + + V +P + +L + + L Y + R + A Sbjct: 200 AHTAE---VRLEEVFVPEENLL--------------GEEGRGLAYALAGLDSGRVGVAAQ 242 Query: 292 ASNALSRAVCIATRYSAVRRQFG 314 A A IA Y+ R QFG Sbjct: 243 AVGIARGAFEIAKAYAEEREQFG 265 >5EZ3-A nrPDB Length = 573 Score = 28.5 bits (62), Expect = 8.8, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 34/82 (41%) Query: 362 LAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPAC 421 +AASD A A + T +K + E + GG+GY+ L + Sbjct: 393 MAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNA 452 Query: 422 TYEGDNVVLQLQVARFLMKTVA 443 +EG V+ L VAR L + A Sbjct: 453 IWEGSGNVMALDVARVLSRAPA 474 >5KUC-A nrPDB Length = 475 Score = 28.5 bits (62), Expect = 9.1, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 16/82 (19%) Query: 132 IGCYAQTELGHGSNVQGLETTATFDPK-------TDEFVIHTPTQTASKWWPGGLGKVST 184 IG Y QT LG N Q L T + + ++ +T+++WW L Sbjct: 47 IGAYIQTGLGLPVNEQQLRTHVNLSQDISIPSDFSQLYDVYCSDKTSAEWWNKNL----- 101 Query: 185 HAVVYARLITNGKDYGIHGFIV 206 Y +I + D +GF V Sbjct: 102 ----YPLIIKSANDIASYGFKV 119 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1W07-A nrPDB 950 0.0 2FON-A nrPDB 912 0.0 1IS2-A nrPDB 742 0.0 5Y9D-A nrPDB 730 0.0 5YS9-A nrPDB 724 0.0 5K3G-A nrPDB 715 0.0 5K3J-A nrPDB 685 0.0 4N5F-A nrPDB 301 7e-82 4U83-A nrPDB 295 3e-80 3B96-A nrPDB 291 5e-79 5LNX-A nrPDB 291 5e-79 5OL2-C nrPDB 288 7e-78 1JQI-A nrPDB 287 7e-78 1UKW-A nrPDB 286 2e-77 2VIG-A nrPDB 282 3e-76 2Z1Q-A nrPDB 280 1e-75 3PFD-A nrPDB 280 2e-75 3OWA-A nrPDB 279 3e-75 4L1F-A nrPDB 275 4e-74 6FAH-C nrPDB 269 4e-72 5IDU-A nrPDB 262 5e-70 2A1T-A nrPDB 254 9e-68 5JSC-A nrPDB 254 1e-67 1RX0-A nrPDB 252 3e-67 4IRN-A nrPDB 251 9e-67 3MDE-A nrPDB 245 3e-65 3NF4-A nrPDB 233 1e-61 2IX5-A nrPDB 233 2e-61 3SF6-A nrPDB 228 8e-60 3MPI-A nrPDB 224 9e-59 6ES9-A nrPDB 220 2e-57 1SIR-A nrPDB 218 5e-57 2PG0-A nrPDB 217 2e-56 3SWO-A nrPDB 213 1e-55 Sequences not found previously or not previously below threshold: 4M9A-A nrPDB 273 2e-73 1BUC-A nrPDB 262 3e-70 2DVL-A nrPDB 233 1e-61 2JIF-A nrPDB 230 2e-60 4KTO-A nrPDB 226 3e-59 4O5M-A nrPDB 218 8e-57 3GNC-A nrPDB 213 2e-55 4IV6-A nrPDB 210 1e-54 2CX9-A nrPDB 209 3e-54 1IVH-A nrPDB 208 8e-54 4W9U-A nrPDB 196 3e-50 2EBA-A nrPDB 195 6e-50 3R7K-A nrPDB 179 3e-45 3P4T-A nrPDB 172 4e-43 5ZW7-A nrPDB 166 4e-41 6CY8-B nrPDB 161 7e-40 5AHS-A nrPDB 151 7e-37 4HR3-A nrPDB 148 1e-35 2WBI-A nrPDB 142 4e-34 4X28-A nrPDB 123 3e-28 1R2J-A nrPDB 118 9e-27 5EZ3-A nrPDB 109 4e-24 4Y9J-A nrPDB 109 6e-24 3U33-A nrPDB 102 6e-22 4RM7-A nrPDB 100 4e-21 3MKH-A nrPDB 93 4e-19 4ZYJ-A nrPDB 85 1e-16 5GJ7-A nrPDB 82 9e-16 3M9V-A nrPDB 78 9e-15 3MXL-A nrPDB 77 2e-14 2C12-A nrPDB 76 5e-14 4XVX-A nrPDB 71 2e-12 5XDD-A nrPDB 66 5e-11 4X28-D nrPDB 66 5e-11 4JEK-A nrPDB 64 2e-10 5LVW-A nrPDB 43 7e-04 2JBS-A nrPDB 41 0.002 2RFQ-A nrPDB 39 0.005 6FYV-A nrPDB 33 0.42 1WU7-A nrPDB 33 0.43 6A2F-A nrPDB 33 0.59 4BQ4-A nrPDB 33 0.63 5Y0R-A nrPDB 31 1.3 5E44-A nrPDB 30 3.1 5LC2-A nrPDB 29 5.0 >1W07-A nrPDB Length = 659 Score = 950 bits (2455), Expect = 0.0, Method: Composition-based stats. Identities = 658/659 (99%), Positives = 658/659 (99%) Query: 1 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE 60 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE Sbjct: 1 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE 60 Query: 61 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK Sbjct: 61 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 Query: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTAT DPKTDEFVIHTPTQTASKWWPGGLG Sbjct: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQTASKWWPGGLG 180 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG Sbjct: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV Sbjct: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE Sbjct: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 Query: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA Sbjct: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 Query: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP Sbjct: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 Query: 481 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE 540 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE Sbjct: 481 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE 540 Query: 541 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA 600 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA Sbjct: 541 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA 600 Query: 601 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQL 659 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQL Sbjct: 601 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQL 659 >2FON-A nrPDB Length = 683 Score = 912 bits (2357), Expect = 0.0, Method: Composition-based stats. Identities = 532/664 (80%), Positives = 604/664 (90%) Query: 1 MEGIDHLADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKE 60 MEG+D+LADER KA FDV++MKIVWAGSRH FE++DRI++LVASDP F K R L RKE Sbjct: 20 MEGVDYLADERKKAGFDVDEMKIVWAGSRHDFELTDRISKLVASDPGFSKEGRTMLPRKE 79 Query: 61 LFKSTLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 LFK+TLRK A+A+KRIIELRL++EEA LR ++D+PA+ DLHWGMF+PAIKGQGT++QQ+ Sbjct: 80 LFKNTLRKAAYAWKRIIELRLSQEEATMLRRYVDEPAFTDLHWGMFIPAIKGQGTDKQQE 139 Query: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 KWL LA KMQIIGCYAQTELGHGSNVQGLETTATFDP+TDEFVIH+PT T+SKWWPGGLG Sbjct: 140 KWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVIHSPTLTSSKWWPGGLG 199 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 KVSTHAVVYARLIT+GKDYG++GFIVQLRSLEDH PLP +TVGDIG K GNGAYNSMDNG Sbjct: 200 KVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVTVGDIGMKFGNGAYNSMDNG 259 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 L FDHVRIPRDQMLMR+S+VT+EG+YV SD+P+QL+YGTMVYVRQ+IVADAS A+SRAV Sbjct: 260 VLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTMVYVRQSIVADASLAMSRAV 319 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 CIATRYSAVRRQFG+ NGG ETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVT+ Sbjct: 320 CIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTQ 379 Query: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 RLAA+DF+TLPEAHACTAGLKSLTT+ATADGIEECRKLCGGHGYL SGLPELFAVYVPA Sbjct: 380 RLAANDFSTLPEAHACTAGLKSLTTSATADGIEECRKLCGGHGYLCSSGLPELFAVYVPA 439 Query: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 CTYEGDNVVLQLQVARFLMKT++QLG+GK PVGT +YMGR HL+QCRS V++AEDWL P Sbjct: 440 CTYEGDNVVLQLQVARFLMKTISQLGTGKKPVGTVSYMGRIEHLMQCRSDVKQAEDWLKP 499 Query: 481 DVVLEAFEARALRMAVTCAKNLSKFENQEQGFQELLADLVEAAIAHCQLIVVSKFIAKLE 540 VLEAFEAR+ RM+V CAKNLSKFENQE+GF EL ADLVEAA+AHCQLIVVSK+I KL+ Sbjct: 500 SAVLEAFEARSARMSVACAKNLSKFENQEEGFAELAADLVEAAVAHCQLIVVSKYIEKLQ 559 Query: 541 QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQVRPNA 600 Q+I GKGVK+QL LC IY+L++LHKH GDFL T IT KQ SLANDQLR+LY+Q+RPNA Sbjct: 560 QNIPGKGVKQQLEVLCGIYSLFILHKHQGDFLGTGYITSKQGSLANDQLRALYSQLRPNA 619 Query: 601 VALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVLQQQLR 660 V+LVDAFNYTDHYL S+LGRYDGNVYPKL+E A KDPLN S + DG+ EY+RP+L+QQLR Sbjct: 620 VSLVDAFNYTDHYLGSILGRYDGNVYPKLYEAAWKDPLNKSDIADGFHEYIRPLLKQQLR 679 Query: 661 TARL 664 TA+L Sbjct: 680 TAKL 683 >1IS2-A nrPDB Length = 661 Score = 742 bits (1914), Expect = 0.0, Method: Composition-based stats. Identities = 298/666 (44%), Positives = 414/666 (62%), Gaps = 22/666 (3%) Query: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 L ER A F+ E + + GS I L+ +DP F+ + L+R + ++ + Sbjct: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 Query: 67 RKCAHAFKRIIELRLN-EEEAGRLRHFIDQ--PAYVDLHWGMFVPAIKGQGTEEQQKKWL 123 +K A K++ E ++ EE ++ + + P +DLH GMF+P + Q T EQQ+++ Sbjct: 65 KKSATMVKKMREYGISDPEEIMWFKNSVHRGHPEPLDLHLGMFLPTLLHQATAEQQERFF 124 Query: 124 SLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVS 183 A ++I G YAQTE+GHG++++GLETTAT+DPKT EF++++PT T+ KWWPGGLGK S Sbjct: 125 MPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 Query: 184 THAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLM 243 HA+V A+LIT G+ YG+H F+V +R + H PLP ITVGDIG K G Y MDNG+L Sbjct: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241 Query: 244 FDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIA 303 D+ RIPR+ MLM+ ++V +G YV + +L YGTMV+VR +V +A+ +LS+A IA Sbjct: 242 MDNYRIPRENMLMKYAQVKPDGTYV-KPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 Query: 304 TRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLA 363 RYSAVRRQ E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + E + Sbjct: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 Query: 364 ASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTY 423 D + LPE HA TAGLK+ TT GIEECR CGGHGY SG+P ++ + PACT+ Sbjct: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 Query: 424 EGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDW------ 477 EG+N V+ LQ ARFLMK Q+ SGK+ G +Y+ L R Q+ W Sbjct: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLND---LPSQRIQPQQVAVWPTMVDI 477 Query: 478 LNPDVVLEAFEARALRMAVTCAKNL----SKFENQEQGFQELLADLVEAAIAHCQLIVVS 533 + + + EA++ RA R+ AKNL S +++E + DLV A+ AHC +VV Sbjct: 478 NSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVK 537 Query: 534 KFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLY 593 F KL + I K V+ L NLC +Y+LY + + GDFL + IT Q S N ++ L Sbjct: 538 VFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELL 596 Query: 594 TQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRP 653 T +RPNAVALVDAF++ D L SVLGRYDGNVY LFE A K PLN + V + Y ++L+P Sbjct: 597 TLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKP 656 Query: 654 VLQQQL 659 LQ +L Sbjct: 657 -LQSKL 661 >5Y9D-A nrPDB Length = 709 Score = 730 bits (1884), Expect = 0.0, Method: Composition-based stats. Identities = 231/671 (34%), Positives = 357/671 (53%), Gaps = 30/671 (4%) Query: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 +A ER K +F V D+ G ++ ++I + DPV + + ++ K T+ Sbjct: 33 MAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTM 92 Query: 67 RKCAHAFKRIIE--LRLNEEEAGRLRHFIDQPAY--VDLHWGMFVPAIKGQGTEEQQKKW 122 + A ++ +L+ A +L +D + +H +F+ +I+G GT EQ K W Sbjct: 93 ERVAALSPYLVTDTEKLSLWRA-QLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYW 151 Query: 123 LSL--ANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 + Q GC+A TELGHGSN++GLETTAT+D +D+F+I+TP A+KWW GG Sbjct: 152 VKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAA 211 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 STH V +A+LI +GKDYG F+V LR++ DHS +++GDIG KMG + +DNG Sbjct: 212 HTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGR---DGVDNG 268 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 ++ F +VRIPR MLMR +KV+ G V QL YG ++ R +++AD+ + R + Sbjct: 269 WIQFTNVRIPRQNMLMRYAKVSDTG-VVTKPALDQLTYGALIRGRVSMIADSFHVSKRFL 327 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 IA RY+ VRRQFG ET++IDY Q RL PLLA YA + + + + + T+ Sbjct: 328 TIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTD 387 Query: 361 RLAASD-------------FATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWC 407 R+ A + E A +AG+K+ TT A I+ECR+ CGGHGY Sbjct: 388 RILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGY 447 Query: 408 SGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQC 467 +G + +A +V CT+EGDN VL L + R L+++ Q+ +GK + Y+G + + Q Sbjct: 448 NGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQN 507 Query: 468 RSGVQKAEDWLNPDVVLEAFEARALRMAVTCA---KNLSKFENQEQGFQELLADLVEAAI 524 G + E L+P+ ++EAF + + + L K N +Q F+EL + A Sbjct: 508 GQGTPR-EQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCAR 566 Query: 525 AHCQLIVVSKFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASL 584 H + ++S F A++ +K L L ++AL+ + + G FL N +TP L Sbjct: 567 IHTRQHLISSFYARIA--TAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDL 624 Query: 585 ANDQLRSLYTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVP 644 N + L VR + L DAF +D ++N+ +G YDGNVY K F + + + P Sbjct: 625 INSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPRP 684 Query: 645 DGYQEYLRPVL 655 Y+ L+P L Sbjct: 685 PYYESTLKPFL 695 >5YS9-A nrPDB Length = 708 Score = 724 bits (1868), Expect = 0.0, Method: Composition-based stats. Identities = 232/670 (34%), Positives = 346/670 (51%), Gaps = 32/670 (4%) Query: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 LA ER K +F ++DM G + +R+ + DPV S + +++L ++ + Sbjct: 27 LAGERAKVKFPIKDMTEFLHGGEENVTMIERLMTELERDPVLNVSGDYDMPKEQLRETAV 86 Query: 67 RKCAHAFKRIIELRLNEEEA---GRLRHFIDQPAYVDL--HWGMFVPAIKGQGTEEQQKK 121 + A + E+EA +L +D + L H G+F+ AI+G GT+EQ Sbjct: 87 ARIAALSGHWK--KDTEKEALLRSQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDY 144 Query: 122 WLSLANK--MQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGL 179 W+ GC+A TELGHGSNV GLETTAT+ TDEF+I+TP A+KWW GG Sbjct: 145 WVRKGAADVKGFYGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGA 204 Query: 180 GKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDN 239 +TH +ARL+ +GKDYG+ F+VQLR + HS +P I +GDIG KMG +++DN Sbjct: 205 AHSATHTACFARLLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGR---DAIDN 261 Query: 240 GFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRA 299 G++ F +VRIPR MLM+ +KV+ G+ V QL YG ++ R T++AD+ R Sbjct: 262 GWIQFTNVRIPRQNMLMKYAKVSSTGK-VSQPPLAQLTYGALIGGRVTMIADSFFVSQRF 320 Query: 300 VCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVT 359 + IA RY+ VRRQFG G ET++IDY Q RL PLLA YA + + + Y T Sbjct: 321 ITIALRYACVRRQFGTTPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTT 380 Query: 360 ERLAASD----------FATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSG 409 + L D L E A +AGLK+ TT A+ I++CR+ CGGHGY +G Sbjct: 381 DLLQTIDPKDKGALGKAIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNG 440 Query: 410 LPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRS 469 + +A +V CT+EGDN VL L + R L+++ GK + Y+ S Sbjct: 441 FGQAYADWVVQCTWEGDNNVLCLSMGRGLIQSCLGHRKGKPLGSSVGYLANKGLEQATLS 500 Query: 470 GVQKAEDWLNPDVVLEAFE---ARALRMAVTCAKNLSKFE-NQEQGFQELLADLVEAAIA 525 G D +P V++EA+E A++ A L+K + +Q F+EL + A Sbjct: 501 G----RDLKDPKVLIEAWEKVANGAIQRATDKFVELTKGGLSPDQAFEELSQQRFQCAKI 556 Query: 526 HCQLIVVSKFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLA 585 H + +V+ F ++ VK L NL ++ L+ + + G FL + PK Sbjct: 557 HTRKHLVTAFYERINASAKAD-VKPYLINLANLFTLWSIEEDSGLFLREGFLQPKDIDQV 615 Query: 586 NDQLRSLYTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPD 645 + + +VR DAF +D ++N+ +G YDG+VY F + + + P Sbjct: 616 TELVNHYCKEVRDQVAGYTDAFGLSDWFINAPIGNYDGDVYKHYFAKVNQQNPAQNPRPP 675 Query: 646 GYQEYLRPVL 655 Y+ LRP L Sbjct: 676 YYESTLRPFL 685 >5K3G-A nrPDB Length = 684 Score = 715 bits (1846), Expect = 0.0, Method: Composition-based stats. Identities = 257/671 (38%), Positives = 382/671 (56%), Gaps = 25/671 (3%) Query: 7 LADERNKAEFDVEDMKI-VWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKST 65 L ER A FD M ++ G A + A+L + + ++R+E + Sbjct: 16 LTAERLTATFDTHAMAAQIYGGEMRARRRREITAKLAEIPELHDSMPLPYMTREEKIMES 75 Query: 66 LRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVD-----LHWGMFVPAIKGQGTEEQQK 120 RK +R+ E+ ++ +AG L H ++ ++ LH MF+PA+ Q ++EQQ Sbjct: 76 ARKLTVLTQRMSEI-IDPTDAGELYHLNNEVLGIEGNPMALHGVMFIPALNAQASDEQQA 134 Query: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLG 180 KWL A + +IIG YAQTE+GHG+N+Q LETTAT+D T EFV+HTP TA KWWPG LG Sbjct: 135 KWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIGTQEFVLHTPKITALKWWPGNLG 194 Query: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 K S +AVV A + GK++G H F+V LR + H PLP IT+GDIG KM AYN +DNG Sbjct: 195 KSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLPGITIGDIGPKM---AYNIVDNG 251 Query: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 FL F++ RIPR +LMR +KV +G Y+ K + Y MV+VR ++ + LS A+ Sbjct: 252 FLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAK-INYSAMVHVRSYMLTGQAIMLSYAL 310 Query: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 IATRYSAVRRQ E +V++Y+TQQ+RLFP +A AYAF+F G LY V + Sbjct: 311 NIATRYSAVRRQGQIDKNEPEVKVLEYQTQQHRLFPFIARAYAFQFAGAETVKLYERVLK 370 Query: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 + + + + + + HA T+GLKS+ T T +GIE+ R CGGHGY S + E++ V + Sbjct: 371 EMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMACGGHGYSMASYISEIYGVAIGG 430 Query: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 CTYEG+N+V+ LQ+AR+L+K+ A + SGK + +G L RS D + Sbjct: 431 CTYEGENMVMLLQLARYLVKSAALVKSGK-----ASQLGPLVAYLGARSEPTSLIDRVPN 485 Query: 481 DVVLE---AFEARALRMAVTCAKN----LSKFENQEQGFQELLADLVEAAIAHCQLIVVS 533 + E F+ A R + A + E +E + + +L A+ H +L +V Sbjct: 486 GGITEYIKTFQHIAKRQTLKAANKFFGLMENGEKREIAWNKSSVELNRASRLHTRLFIVE 545 Query: 534 KFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLY 593 F A+ +IG +K+ L++L +++ Y L L ++ Q DQL Sbjct: 546 AF-ARRVNEIGDITIKEALSDLLHLHVNYELLDVATYALEDGFMSSTQLDYVRDQLYFYL 604 Query: 594 TQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRP 653 ++RPNAV+L+D++ ++D L SVLGR DG+VY LF+ A + PLN + V YL+P Sbjct: 605 QKIRPNAVSLLDSWEFSDRELRSVLGRRDGHVYENLFKWAKESPLNKTDVLPSVDTYLKP 664 Query: 654 VLQQQLRTARL 664 ++++ R ++L Sbjct: 665 MMEKA-RQSKL 674 >5K3J-A nrPDB Length = 674 Score = 685 bits (1768), Expect = 0.0, Method: Composition-based stats. Identities = 248/662 (37%), Positives = 370/662 (55%), Gaps = 28/662 (4%) Query: 7 LADERNKAEFDVEDMKIVWAGSRH-AFEVSDRIARLVASDPVFEKSNRARLSRKELFKST 65 L +ER A FD + M V GS A + + + + L+R+E Sbjct: 14 LLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKIPELADIKPYPFLTREEKVTEG 73 Query: 66 LRKCAHAFKRIIEL--RLNEEEAGRLRHFI--DQPAYVDLHWGMFVPAIKGQGTEEQQKK 121 RK + K + +L R NEEE+ L + + LH +F+P ++ Q ++EQQ+K Sbjct: 74 TRKISILTKYLNQLIDRDNEEESLHLHREVIGYEGHPFALHDALFIPTLQSQASDEQQEK 133 Query: 122 WLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGK 181 WL A + +IIGCYAQTELGHGSN++ LETTA +D + EFV+HTPT TA KWWPG LGK Sbjct: 134 WLERARRREIIGCYAQTELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALKWWPGALGK 193 Query: 182 VSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGF 241 +A+V A LI +YG H F+VQLR + H PL +TVGDIG KM +N+ DNG+ Sbjct: 194 SCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMN---FNAADNGY 250 Query: 242 LMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVC 301 L +++R+PR +LMR KV +G YV K + Y MV +R + + L+ A+ Sbjct: 251 LGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAK-IGYSGMVKIRSQMAMEQGLFLAHALT 309 Query: 302 IATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTER 361 IA RYSAVRRQ + +E +V+DY+TQQ+RLFP LA AYAF F G LY+ + + Sbjct: 310 IAARYSAVRRQGHLDDKQVEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKD 369 Query: 362 LAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPAC 421 + + + + + HA T+GLKS+ T +GIE+ R CGGHGY S + ++ + + C Sbjct: 370 VDMGNTSGMADLHALTSGLKSVVAHETGEGIEQARMACGGHGYSMASYISVVYGIAIGGC 429 Query: 422 TYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNPD 481 TY G+N+V+ LQ+AR+L+K+V + +GK +G A L +S D + + Sbjct: 430 TYAGENMVMLLQLARYLVKSVELIKAGK-----AKKLGPVASYLADKS---DETDLTSLN 481 Query: 482 VVLEAFEARALRMAVTCAKNLSK----FENQEQGFQELLADLVEAAIAHCQLIVVSKFIA 537 ++ FE A R A + K E++E + + +L A+ H +L ++ F+ Sbjct: 482 GYVKMFENMARRQAWKATEKFLKLMESGESREVAWNKSAVELTRASRLHTRLFIIEAFMR 541 Query: 538 KLE--QDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQ 595 ++ +DI K V L +L Y L + + +F+S Q DQL + Sbjct: 542 RVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALEFMSFT-----QLDYVRDQLYLYLEK 596 Query: 596 VRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRPVL 655 +RPNAV+LVD+F +D L SVLGR DG+VY LF+ A PLN++ V ++YL+P++ Sbjct: 597 IRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPLNNADVLPSVEKYLKPMM 656 Query: 656 QQ 657 ++ Sbjct: 657 EK 658 >4N5F-A nrPDB Length = 385 Score = 301 bits (770), Expect = 7e-82, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 129/345 (37%), Gaps = 55/345 (15%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 + +H + I G GT Q+ +WL+ ++IG + TE GS L T A + Sbjct: 93 TMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVIGAFCLTEPHAGSEANNLRTRA--E 150 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 + ++V++ Q + G+ + A+V+A GI F+V + Sbjct: 151 LRDGQWVLNGAKQFVTN------GQRAGVAIVFAMTDPEAGKRGISAFLVP-------TD 197 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P VG KMG A D + F++ IP D +L GE + ++ Sbjct: 198 TPGFIVGKPEKKMGIRAS---DTCPITFENCAIPEDNLL------GNRGEGL------KI 242 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQQNR 333 + R I A A A A RY+ R QFG A + I+ ++ D Q N Sbjct: 243 ALSNLEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINA 302 Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 L+ A R G L L +L AS+ A Sbjct: 303 ARLLVHHAAKLRTAG--LPCLSEASQAKLFASEMAER--------------------VCS 340 Query: 394 ECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 + ++ GG+GYL + + YEG + V ++ +AR L Sbjct: 341 DAIQIHGGYGYLVDYEVERHYRDARITQIYEGTSEVQRMVIARQL 385 >4U83-A nrPDB Length = 382 Score = 295 bits (755), Expect = 3e-80, Method: Composition-based stats. Identities = 80/346 (23%), Positives = 126/346 (36%), Gaps = 55/346 (15%) Query: 96 PAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATF 155 V +H + I GTE+Q++++L + IG +A TE GS+ L+T A Sbjct: 89 STIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARL 148 Query: 156 DPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHS 215 D D +VI Q + GK +V+A GI FIV + Sbjct: 149 D--GDHYVIDGSKQFIT------SGKNGNVVIVFAVTDPAAGKKGISAFIVP-------T 193 Query: 216 PLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQ 275 P V + K+G +S D L F ++R+P + L EGE + Sbjct: 194 DTPGYEVMSVEHKLGQ---HSSDTCALGFTNMRVPVENRL------GAEGEGY------K 238 Query: 276 LVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAH---NGGIETQVIDYKTQQN 332 + + R I A A A A Y+ R FG + + ++ D T+ Sbjct: 239 IALANLEGGRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIE 298 Query: 333 RLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGI 392 ++ A A R G+ L +L AS+ A Sbjct: 299 TARQMVLHAAALREAGK--PCLTEASMAKLVASEMAE--------------------QVC 336 Query: 393 EECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 ++ GG+GYL + ++ YEG + V +L +AR L Sbjct: 337 SAAIQIHGGYGYLADYPVERIYRDVRVCQIYEGTSDVQRLVIARGL 382 >3B96-A nrPDB Length = 587 Score = 291 bits (745), Expect = 5e-79, Method: Composition-based stats. Identities = 81/382 (21%), Positives = 149/382 (39%), Gaps = 57/382 (14%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 + H + I GT+ Q++K+L + + + TE GS+ + T+A P Sbjct: 110 LGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPC 169 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYG-----IHGFIVQLRSLED 213 + ++ SK W G ++ V+A+ G I F+V+ Sbjct: 170 GKYYTLN-----GSKLWISNGG-LADIFTVFAKTPVTDPATGAVKEKITAFVVER----- 218 Query: 214 HSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVP 273 IT G KMG A N+ + + FD VR+P + +L + Sbjct: 219 --GFGGITHGPPEKKMGIKASNTAE---VFFDGVRVPSENVLGEVGS------------G 261 Query: 274 KQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNR 333 ++ + R + A + + + A ++ R QFG ++ ++ Q + Sbjct: 262 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGE-------KIHNFGLIQEK 314 Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 L A ++V E + ++ + ++ A+DF A K + A + Sbjct: 315 L----ARMVMLQYVTESMAYMVSANMDQ-GATDFQIEA------AISKIFGSEAAWKVTD 363 Query: 394 ECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVA-RFLM---KTVAQLGSG- 448 EC ++ GG G++ G+ + +EG N +L+L VA + M K ++ LGS Sbjct: 364 ECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSAL 423 Query: 449 KVPVGTTA-YMGRAAHLLQCRS 469 K P G +G A L+ R+ Sbjct: 424 KNPFGNAGLLLGEAGKQLRRRA 445 >5LNX-A nrPDB Length = 379 Score = 291 bits (745), Expect = 5e-79, Method: Composition-based stats. Identities = 77/344 (22%), Positives = 133/344 (38%), Gaps = 55/344 (15%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 + +H + I G EEQ+ K++ +G +A TE GS+ L TTA K Sbjct: 85 LSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAI--KK 142 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 +++++ SK + G + + +A + +GI FIV+ P Sbjct: 143 NGKYLLN-----GSKIFITNGG-AADIYITFALTAPDQGRHGISAFIVEKN-------TP 189 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 TVG K+G N+ + L+FD+ +P +L +EG+ + Sbjct: 190 GFTVGKKERKLGLYGSNTTE---LIFDNAEVPEANLL------GKEGDGF------HIAM 234 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQQNRLF 335 + R I A A A+ A Y+ R QFG A N GI ++ D T+ Sbjct: 235 ANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAAR 294 Query: 336 PLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEEC 395 L+ A G L A++ + A A +K+ + Sbjct: 295 HLVYHAADLHNRG-------------LNCGKEASMAKQFASDAAVKA---------ALDA 332 Query: 396 RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM 439 ++ GG+GY+ + L YEG N + +L ++++L+ Sbjct: 333 VQIYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLL 376 >5OL2-C nrPDB Length = 378 Score = 288 bits (736), Expect = 7e-78, Method: Composition-based stats. Identities = 71/342 (20%), Positives = 123/342 (35%), Gaps = 49/342 (14%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 + H + I G EEQ++K+L + +G + TE G++ G +TTA D Sbjct: 86 LSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLD-- 143 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 DE++++ + G VV A + + GI FIV+ P Sbjct: 144 GDEYILNGSKIFITNAIAG------DIYVVMAMTDKSKGNKGISAFIVE-------KGTP 190 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 + G KMG + + L+F+ RIP++ +L +EG+ ++ Sbjct: 191 GFSFGVKEKKMGIRGSATSE---LIFEDCRIPKENLL------GKEGQGF------KIAM 235 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLL 338 T+ R I A A A+ +Y R QFG + ++ Q +L + Sbjct: 236 STLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGR-------PLSKFQNTQFQLADME 288 Query: 339 ASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKL 398 A R + D A A K + + +L Sbjct: 289 VKVQAARHLVYQAA----------INKDLGKPYGVEAAMA--KLFAAETAMEVTTKAVQL 336 Query: 399 CGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 GG+GY + + YEG + V ++ ++ L+K Sbjct: 337 HGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK 378 >1JQI-A nrPDB Length = 388 Score = 287 bits (735), Expect = 7e-78, Method: Composition-based stats. Identities = 72/368 (19%), Positives = 142/368 (38%), Gaps = 57/368 (15%) Query: 78 ELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQ 137 + EE R + ++ +++ I G+ +Q+++W++ IGC+A Sbjct: 73 AYSIALEEIS--RGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFAL 130 Query: 138 TELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGK 197 +E G+GS+ TTA + D +V++ + W ++ VV+A + + Sbjct: 131 SEPGNGSDAGAASTTAR--EEGDSWVLNGTKAWITNSW------EASATVVFASTDRSRQ 182 Query: 198 DYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMR 257 + GI F+V + P P +T+G K+G A ++ + L+F+ RIP++ +L Sbjct: 183 NKGISAFLVPM-------PTPGLTLGKKEDKLGIRASSTAN---LIFEDCRIPKENLLGE 232 Query: 258 LSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAH- 316 + ++ T+ R I + A ++ A +Y+ R FGA Sbjct: 233 ------------PGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPL 280 Query: 317 --NGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAH 374 I+ ++ D L SA + LK T+ A + A Sbjct: 281 TKLQNIQFKLADMALA-------LESARLLTWRAAMLKDNKKPFTKESAMAKLA------ 327 Query: 375 ACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQV 434 + A + ++ GG GY+ + YEG + + +L + Sbjct: 328 ---------ASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVI 378 Query: 435 ARFLMKTV 442 A L+++ Sbjct: 379 AGHLLRSY 386 >1UKW-A nrPDB Length = 379 Score = 286 bits (732), Expect = 2e-77, Method: Composition-based stats. Identities = 73/343 (21%), Positives = 139/343 (40%), Gaps = 49/343 (14%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 + + + + + GTEEQ++++L + + +A +E G+GS+ L+T A + Sbjct: 86 IPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIR--Q 143 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 D +V++ +K W G+ VV+A + + G+ +V+ P Sbjct: 144 GDHYVLN-----GTKMWISNGGEAEWV-VVFATVNPELRHKGVVALVVER-------GTP 190 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 I KMG A + + L+F+ V++P + L EGE ++ Sbjct: 191 GFKAIKIHGKMGQRASGTYE---LVFEDVKVPVENRL------GEEGEGF------KIAM 235 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLL 338 T+ R + A + RA+ A +Y+ R FG + +++ Q +L +L Sbjct: 236 QTLNKTRIPVAAGSVGVARRALDEARKYAKEREAFGE-------PIANFQAIQFKLVDML 288 Query: 339 ASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKL 398 R + WL LP AHA +A K+ + + + ++ Sbjct: 289 IGIETARMYTYYAAWLADQ-----------GLPHAHA-SAIAKAYASEIAFEAANQAIQI 336 Query: 399 CGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKT 441 GG+GY+ + +L YEG N + +L +AR ++ Sbjct: 337 HGGYGYVREFPVEKLLRDVKLNQIYEGTNEIQRLIIARHILAA 379 >2VIG-A nrPDB Length = 391 Score = 282 bits (721), Expect = 3e-76, Method: Composition-based stats. Identities = 76/365 (20%), Positives = 140/365 (38%), Gaps = 51/365 (13%) Query: 78 ELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQ 137 + EE R + ++ +++ I G++EQ++ W++ IGC+A Sbjct: 69 AYAIAMEEIS--RGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFAL 126 Query: 138 TELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGK 197 +E G+GS+ TTA + D +V++ + W ++ AVV+A + Sbjct: 127 SEPGNGSDAGAASTTARAE--GDSWVLNGTKAWITNAW------EASAAVVFASTDRALQ 178 Query: 198 DYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMR 257 + I F+V + P P +T+G K+G ++ + L+F+ RIP+D +L Sbjct: 179 NKSISAFLVPM-------PTPGLTLGKKEDKLGIRGSSTAN---LIFEDCRIPKDSILGE 228 Query: 258 LSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHN 317 + ++ T+ R I + A A+ A Y+ R FGA Sbjct: 229 ------------PGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPL 276 Query: 318 GGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACT 377 + QVI +K L L SA + LK + A + A Sbjct: 277 --TKLQVIQFKLADMALA--LESARLLTWRAAMLKDNKKPFIKEAAMAKLA--------- 323 Query: 378 AGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARF 437 + A + ++ GG GY+ + YEG + + +L +A Sbjct: 324 ------ASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGH 377 Query: 438 LMKTV 442 L+++ Sbjct: 378 LLRSY 382 >2Z1Q-A nrPDB Length = 577 Score = 280 bits (716), Expect = 1e-75, Method: Composition-based stats. Identities = 72/392 (18%), Positives = 142/392 (36%), Gaps = 44/392 (11%) Query: 86 AGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSN 145 A L H + + GTEEQ++K+L + I Y TE G GS+ Sbjct: 97 AEELSGSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAAYCLTEPGSGSD 156 Query: 146 VQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFI 205 +T AT ++++ K W G + V+A++ F+ Sbjct: 157 ALAAKTRATLSEDGKHYILN-----GVKQWISNAG-FAHLFTVFAKVDGEH----FTAFL 206 Query: 206 VQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREG 265 V+ P ++ G KMG A ++ ++ + V++P + +L + K Sbjct: 207 VER-------DTPGLSFGPEEKKMGIKASSTRQ---VILEDVKVPVENVLGEIGK----- 251 Query: 266 EYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVI 325 ++ + + R + A A RA+ ++ +Y+ R QFG G Sbjct: 252 -------GHKIAFNVLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIG------- 297 Query: 326 DYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVT--ERLAASDFATLPEAHACTAGLKSL 383 + Q +L + + YA L + ++ + A + E + +K L Sbjct: 298 RFGLIQQKLGEMASRIYAAESAVYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVL 357 Query: 384 TTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVA 443 + ++E ++ GG+GY + + +EG N + +L + L++ Sbjct: 358 GSEVLDYVVDEGVQIHGGYGYSQEYPIERAYRDARINRIFEGTNEINRLLIPGMLLRRAL 417 Query: 444 QLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAE 475 G++P+ A + L + E Sbjct: 418 ---KGQLPLMQAAQRLQKELLEPSFEEPEDLE 446 >3PFD-A nrPDB Length = 393 Score = 280 bits (715), Expect = 2e-75, Method: Composition-based stats. Identities = 77/360 (21%), Positives = 137/360 (38%), Gaps = 63/360 (17%) Query: 92 FIDQPAYVDLHWGMFVPAIKG--------QGTEEQQKKWLSLANKMQIIGCYAQTELGHG 143 I++ A VD + +PA+ +G+EE +K+ L + + YA +E G Sbjct: 86 VIEEVARVDCSASL-IPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASYALSEREAG 144 Query: 144 SNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHG 203 S+ + T A D D+++++ SK W GK + + V A + GI Sbjct: 145 SDAASMRTRAVAD--GDDWILN-----GSKCWITNGGKSTWY-TVMAVTDPDKGANGISA 196 Query: 204 FIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTR 263 F+V H TVG K+G + + L F++ RIP D+++ Sbjct: 197 FMV-------HKDDEGFTVGPKERKLGIKGSPTTE---LYFENCRIPGDRIIGE------ 240 Query: 264 EGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGI 320 + T+ + R TI A A A+ A Y+ R+QFG + N G+ Sbjct: 241 ------PGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGV 294 Query: 321 ETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGL 380 + + D + ++ SA A GE + +A Sbjct: 295 QFMLADMAMKIEAARLMVYSAAARAERGE---------------------GDLGFISAAS 333 Query: 381 KSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 K + + + +L GG+GY + + YEG N + ++ ++R L++ Sbjct: 334 KCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR 393 >3OWA-A nrPDB Length = 597 Score = 279 bits (713), Expect = 3e-75, Method: Composition-based stats. Identities = 99/509 (19%), Positives = 187/509 (36%), Gaps = 67/509 (13%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H G+ I G EEQ+KK+L L + + YA TE G GS+ G +TTA + + Sbjct: 118 HVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTH 177 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 +V++ K W + +VYA++ FIV+ ++ Sbjct: 178 YVLN-----GEKQWITNSA-FADVFIVYAKIDGEH----FSAFIVE-------KDYAGVS 220 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 KMG ++ L+ + +P++ +L + K + + + Sbjct: 221 TSPEEKKMGIKCSST---RTLILEDALVPKENLLGEIGK------------GHIIAFNIL 265 Query: 282 VYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASA 341 R + + RAV I+ +Y+ R+QF + + + Q +L + A Sbjct: 266 NIGRYKLGVGTVGSAKRAVEISAQYANQRQQF-------KQPIARFPLIQEKLANMAAKT 318 Query: 342 YA-----FRFVGEWLKWLYTDVTERL--AASDFATLPEAHACTAGLKSLTTTATADGIEE 394 YA +R VG + + T E + + A++ E + K + ++E Sbjct: 319 YAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDE 378 Query: 395 CRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQV-ARFLMKTVAQLGSGKVPVG 453 ++ GG+G++ + ++ +EG N + +L V FL K + G++P+ Sbjct: 379 GVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRKAM----KGELPLL 434 Query: 454 TTAYMGRAAHLLQCRSGVQKAEDWLNPDVVLEAFEARALRMAVTCAKNLSKFENQEQGFQ 513 A + ++ V E ++ + L +A A+ K ++EQ Sbjct: 435 QKAQKLQEELMMMMPEEVGD-EPLALQKYLVNNAKKIGLMVAGLAAQKYGKALDKEQEI- 492 Query: 514 ELLADLVEAAIAHCQLIVVSKFIAKLEQDIGGKGVKKQLNNLCYI-----YALYLLHKHL 568 LV A L + + + E+ I G++K + Y A + H Sbjct: 493 -----LVNIADIVSNLYAMESAVLRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEIEAHA 547 Query: 569 GDFLSTNCITPKQASLANDQLRSLYTQVR 597 I + + L SL R Sbjct: 548 ----KETLIAVENGDMLRMMLSSLRKLTR 572 >4L1F-A nrPDB Length = 383 Score = 275 bits (703), Expect = 4e-74, Method: Composition-based stats. Identities = 74/353 (20%), Positives = 136/353 (38%), Gaps = 57/353 (16%) Query: 93 IDQPAYVDLHW--GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLE 150 +D + L + I GTEEQ++K+L+ + +G + TE G++ + Sbjct: 79 VDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHVGAFGLTEPSAGTDASAQQ 138 Query: 151 TTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRS 210 TTA K D+++++ SK + GK + VV+A + +GI FI++ Sbjct: 139 TTAVL--KGDKYILN-----GSKIFITN-GKEADTYVVFAMTDKSQGVHGISAFILE--- 187 Query: 211 LEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPS 270 +P G I KMG ++ L+F+ +P++ +L +EGE Sbjct: 188 ----KGMPGFRFGKIEDKMGG---HTSITAELIFEDCEVPKENLL------GKEGEGF-- 232 Query: 271 DVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHN---GGIETQVIDY 327 ++ T+ R + A A A+ A +YS R QFG ++ + D Sbjct: 233 ----KIAMETLDGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADM 288 Query: 328 KTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTA 387 T+ L+ A + G+ S+ A + K + Sbjct: 289 ATKIEAARYLVYHAAMLKNEGK-------------PYSEAAAMA---------KCFASDV 326 Query: 388 TADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 + + ++ GG+GY YEG N V+++ +R L++ Sbjct: 327 AMEVTTDAVQIFGGYGYTVDYPAERYMRNAKITQIYEGTNQVMRIVTSRALLR 379 >4M9A-A nrPDB Length = 385 Score = 273 bits (697), Expect = 2e-73, Method: Composition-based stats. Identities = 75/345 (21%), Positives = 130/345 (37%), Gaps = 55/345 (15%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 V +H + + GT EQ+++WL + +G ++ TE GS L T A + Sbjct: 93 TLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTVGAFSLTEPHAGSEAHNLRTRA--E 150 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 + +++++ Q + G + A+V+A + G+ F+V + Sbjct: 151 LRDGKWILNGSKQFVTN------GARAGLAIVFAMTDPDEGKRGLSAFVVP-------TD 197 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P VG KMG A D + ++ IP++ +L + GE + ++ Sbjct: 198 TPGFIVGKPEKKMGIRAS---DTCPITLENCAIPQENLL------GKRGEGL------KI 242 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQQNR 333 + R I A A+ A A RY+ R QFG A + I ++ + TQ N Sbjct: 243 ALSNLEGGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINA 302 Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 L A R G L L +L AS+ A Sbjct: 303 ARLLTHHAARLRTAG--LPCLSEASQAKLFASEMAE--------------------AVCS 340 Query: 394 ECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 + ++ GG+G+L + + YEG + V ++ +AR L Sbjct: 341 DAIQIHGGYGFLVDYEVERHYRDARITQIYEGTSEVQRMVIARQL 385 >6FAH-C nrPDB Length = 379 Score = 269 bits (686), Expect = 4e-72, Method: Composition-based stats. Identities = 64/343 (18%), Positives = 130/343 (37%), Gaps = 49/343 (14%) Query: 98 YVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDP 157 Y+ + + GTEEQ +K+L + +A TE G GS+ G+ TTA Sbjct: 85 YLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAV--D 142 Query: 158 KTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPL 217 D ++++ + + + AV+YA+ + GI FIV L+S Sbjct: 143 MGDYYLLNGRKTFIT------MAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSE------ 190 Query: 218 PNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLV 277 +++G KMG + D ++ + V++P++ L ++K Sbjct: 191 -GVSMGKNEHKMGLIGCATSD---IIMEDVKVPKENRLGEVNKGFSN------------A 234 Query: 278 YGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL 337 T+ R + + + A+ A +Y+ R+QFG ++ D++ + + Sbjct: 235 MKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFG-------KRIADFQAIAFMIADM 287 Query: 338 LASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRK 397 A + + L + + A K + + + + Sbjct: 288 ATKLEAAKLLVYNAASLMDNKKNATKEASMA------------KFYASEICNEICAKAVQ 335 Query: 398 LCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 + GG+GY+ + ++ YEG + V Q+ ++ L+K Sbjct: 336 IHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLK 378 >1BUC-A nrPDB Length = 383 Score = 262 bits (670), Expect = 3e-70, Method: Composition-based stats. Identities = 71/340 (20%), Positives = 119/340 (35%), Gaps = 54/340 (15%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 + I GTE Q++K+L + +G + TE G++ G +T AT + + Sbjct: 95 SLCANPIWQFGTEAQKEKFLVPLVEGTKLGAFGLTEPNAGTDASGQQTIATKNDDGT-YT 153 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 ++ SK + G + +V+A + ++GI FI++ P T G Sbjct: 154 LN-----GSKIFITNGG-AADIYIVFAMTDKSKGNHGITAFILE-------DGTPGFTYG 200 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 KMG ++ L+F V++P + ML K ++ T+ Sbjct: 201 KKEDKMGI---HTSQTMELVFQDVKVPAENMLGEEGK------------GFKIAMMTLDG 245 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHN---GGIETQVIDYKTQQNRLFPLLAS 340 R + A A A+ A YS R QFG I ++ D K Q L+ Sbjct: 246 GRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAARNLVYK 305 Query: 341 AYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCG 400 A + G+ + + ASD A E ++ G Sbjct: 306 AACKKQEGK--PFTVDAAIAKRVASDVA--------------------MRVTTEAVQIFG 343 Query: 401 GHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 G+GY + YEG N V + L++ Sbjct: 344 GYGYSEEYPVARHMRDAKITQIYEGTNEVQLMVTGGALLR 383 >5IDU-A nrPDB Length = 410 Score = 262 bits (668), Expect = 5e-70, Method: Composition-based stats. Identities = 81/349 (23%), Positives = 131/349 (37%), Gaps = 57/349 (16%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 G+ AI GT EQ+ ++L +K + I +A +E GS+V + A + D +V Sbjct: 113 GLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAE--GDCYV 170 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 I K W G ++ VV+AR GI FIV + P + Sbjct: 171 ID-----GDKTWISNGG-IADFYVVFARTGEAPGARGISAFIVD-------ADTPGLQ-- 215 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 I ++ A + + L FD R+PR QML ++ T+ Sbjct: 216 -IAERIDVIAPHPLAR--LHFDSARVPRSQMLG------------APGEGFKIAMRTLDV 260 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL---LAS 340 R ++ A + RA+ +A R+ FG G D++ Q +L + + S Sbjct: 261 FRTSVAAASLGFARRALQEGLARAASRKMFGQTLG-------DFQLTQTKLAQMALTIDS 313 Query: 341 AYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCG 400 + + WL+ +VT A + + HA + I+ +L G Sbjct: 314 SALLVYRAAWLRDQGENVTRE------AAMAKWHASEGAQQV---------IDAAVQLWG 358 Query: 401 GHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGK 449 G G + + L+ YEG V QL V R L+K A + Sbjct: 359 GMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHAAQRQQE 407 >2A1T-A nrPDB Length = 421 Score = 254 bits (649), Expect = 9e-68, Method: Composition-based stats. Identities = 69/337 (20%), Positives = 128/337 (37%), Gaps = 52/337 (15%) Query: 103 WGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEF 162 + I G ++Q+KK+L + ++ Y TE G GS+V G++T A + K DE+ Sbjct: 126 NSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEY 183 Query: 163 VIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGK---DYGIHGFIVQLRSLEDHSPLPN 219 +I+ K W GK + + ++ AR + K + GFIV+ + P Sbjct: 184 IIN-----GQKMWITNGGKANWYFLL-ARSDPDPKAPANKAFTGFIVE-------ADTPG 230 Query: 220 ITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYG 279 I +G MG D ++F+ V++P++ +L + ++ G Sbjct: 231 IQIGRKELNMGQ---RCSDTRGIVFEDVKVPKENVL------------IGDGAGFKVAMG 275 Query: 280 TMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLA 339 R + A A RA+ AT+Y+ R+ FG +++++ L + Sbjct: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFG-------KLLVEHQAISFMLAEMAM 328 Query: 340 SAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLC 399 R + W + A K+ + ++ Sbjct: 329 KVELARMSYQRAAWEVDSGRRNTYYASIA------------KAFAGDIANQLATDAVQIL 376 Query: 400 GGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 GG+G+ + +L YEG + + +L VAR Sbjct: 377 GGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 >5JSC-A nrPDB Length = 410 Score = 254 bits (647), Expect = 1e-67, Method: Composition-based stats. Identities = 77/340 (22%), Positives = 126/340 (37%), Gaps = 57/340 (16%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 G+ AI GT EQ+ ++L I +A +E GS+V + +A D D +V Sbjct: 113 GLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSARED--GDAYV 170 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 + K W G ++ VV+AR GI F+V + P + Sbjct: 171 LD-----GDKTWISNGG-IADFYVVFARTGEAPGARGISAFVVD-------ADTPGL--- 214 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 +I ++ A + + L F R+PR QML +L T+ Sbjct: 215 EIAERIDVIAPHPLAR--LHFAGARVPRSQMLG------------APGEGFKLAMRTLDI 260 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL---LAS 340 R ++ A + A+ +A R+ FG G D++ Q +L + + S Sbjct: 261 FRTSVAAASLGFARHAMAEGVARAASRKMFGQTLG-------DFQLTQAKLAQMALTIDS 313 Query: 341 AYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCG 400 + + WL+ +VT A + + HA + I+ +L G Sbjct: 314 SALLVYRAAWLRDQGENVTRE------AAMAKWHASEGAQQV---------IDAAVQLYG 358 Query: 401 GHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 G G + + L+ YEG V QL V R L+K Sbjct: 359 GMGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGRDLLK 398 >1RX0-A nrPDB Length = 393 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 72/345 (20%), Positives = 127/345 (36%), Gaps = 50/345 (14%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 AY+ +H M I G EEQ+ K+ M+ Y TE G GS+ L T+A Sbjct: 99 AYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSA--K 155 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 + D ++++ SK + G G+ S VV R G GI +V+ Sbjct: 156 KQGDHYILN-----GSKAFISGAGE-SDIYVVMCRTGGPGP-KGISCIVVE-------KG 201 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P ++ G K+G +NS ++F+ +P ++ EG+ + Sbjct: 202 TPGLSFGKKEKKVG---WNSQPTRAVIFEDCAVPVAN------RIGSEGQGFL------I 246 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 + R I + + A +V + + VR+QFG + + Q L Sbjct: 247 AVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGE-------PLASNQYLQFTLAD 299 Query: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECR 396 + A R + A + +A A + K T + Sbjct: 300 MATRLVAARL-----------MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQAL 348 Query: 397 KLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKT 441 ++ GG+GYL + + EG N V+++ ++R L++ Sbjct: 349 QMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 393 >4IRN-A nrPDB Length = 416 Score = 251 bits (640), Expect = 9e-67, Method: Composition-based stats. Identities = 65/340 (19%), Positives = 134/340 (39%), Gaps = 49/340 (14%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 ++ H + GTEEQ++K+L L + I +A TE GS++ L+TTA D Sbjct: 124 MNAHIWACEMPLLTFGTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKD-- 181 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 D+++++ + G ++ +++A + + G+ F+++ P Sbjct: 182 GDKYILNGYKHYVTN------GTIADLFIIFATIDPSLGKEGLTTFMIE-------KDTP 228 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 + + +KMG + + L ++ + L + Sbjct: 229 GLILSKPISKMGM---RTAEVPELRLENCEVSAANRLGE------------EGTGLAIFN 273 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLL 338 +M + R I+A A + R + + RY+ +QFG G + Q++ K + +L Sbjct: 274 HSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIG--KFQLVANKLVEMKLRLEN 331 Query: 339 ASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKL 398 A AY ++ + W+ + L + A L + A E ++ Sbjct: 332 AKAYLYK-----VAWMKENKQMALLEASMANL------------YISEAWVQSCLEAIEI 374 Query: 399 CGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 G +GYL + L + + Y G + + ++ +A+FL Sbjct: 375 HGAYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAKFL 414 >3MDE-A nrPDB Length = 385 Score = 245 bits (626), Expect = 3e-65, Method: Composition-based stats. Identities = 70/337 (20%), Positives = 126/337 (37%), Gaps = 52/337 (15%) Query: 103 WGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEF 162 + + G +QQKK+L + ++ Y TE G GS+V G++T A + K DE+ Sbjct: 91 NTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEY 148 Query: 163 VIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGK---DYGIHGFIVQLRSLEDHSPLPN 219 +I+ K W GK + + ++ AR + K GFIV+ + P Sbjct: 149 IIN-----GQKMWITNGGKANWYFLL-ARSDPDPKAPASKAFTGFIVE-------ADTPG 195 Query: 220 ITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYG 279 + +G MG D ++F+ VR+P++ +L GE ++ G Sbjct: 196 VQIGRKEINMGQ---RCSDTRGIVFEDVRVPKENVL--------TGEG----AGFKIAMG 240 Query: 280 TMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLA 339 T R + A A RA+ AT+Y+ R+ FG + +++ L + Sbjct: 241 TFDKTRPPVAAGAVGLAQRALDEATKYALERKTFG-------KLLAEHQGISFLLADMAM 293 Query: 340 SAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLC 399 R + W + A K+ + ++ Sbjct: 294 KVELARLSYQRAAWEIDSGRRNTYYASIA------------KAYAADIANQLATDAVQVF 341 Query: 400 GGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 GG+G+ + +L YEG + ++ +AR Sbjct: 342 GGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRIIIAR 378 >2DVL-A nrPDB Length = 372 Score = 233 bits (595), Expect = 1e-61, Method: Composition-based stats. Identities = 68/345 (19%), Positives = 121/345 (35%), Gaps = 60/345 (17%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 V + G+ + G+E Q++++L + + IG + TE GS+ + L A Sbjct: 85 VSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFCLTEPQAGSDAKSLRAEARRVKG 144 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 FV++ K W G + VV AR + GI F+V+ P Sbjct: 145 G--FVLN-----GVKSWITSAGH-AHLYVVMART-----EKGISAFLVE-------KGTP 184 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 ++ G KMG A ++ + + + V +P + +L + Sbjct: 185 GLSFGRPEEKMGLHAAHTAE---VRLEEVFVPEENLLGEEGR------------GLAYAL 229 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGA---HNGGIETQVIDYKTQQNRLF 335 + R + A A A IA Y+ R QFG + I ++ D + Sbjct: 230 AGLDSGRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVK----- 284 Query: 336 PLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEEC 395 +A+A A K T +A+ + A + E Sbjct: 285 --IAAARALVLEAARKKDRGERFTLEASAAKLFA---------------SAAAVEVTREA 327 Query: 396 RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 ++ GG+GY + + YEG + + +L +AR L + Sbjct: 328 VQVLGGYGYHRDYRVERYYRDAKVTEIYEGTSEIQRLVIARELYR 372 >3NF4-A nrPDB Length = 387 Score = 233 bits (595), Expect = 1e-61, Method: Composition-based stats. Identities = 76/342 (22%), Positives = 128/342 (37%), Gaps = 52/342 (15%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 V +H + + GTEEQ+K+WL + IG Y+ +E GS+ L AT P Sbjct: 98 VSVH-SLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAAT--PT 154 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLP 218 +VI+ SK W GK + ++AR G+ F+V + P Sbjct: 155 DGGYVIN-----GSKSWITHGGK-ADFYTLFARTGE--GSRGVSCFLVP-------ADQP 199 Query: 219 NITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVY 278 ++ G KMG +++ +D+ RI D+ ++ EG+ + Q+ + Sbjct: 200 GLSFGKPEEKMGL---HAVPTTSAFYDNARIDADR------RIGEEGQGL------QIAF 244 Query: 279 GTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLL 338 + R I A A+ A+ A Y+ R FG ++ID++ L + Sbjct: 245 SALDSGRLGIAAVATGLAQAALDEAVAYANERTAFGR-------KIIDHQGLGFLLADMA 297 Query: 339 ASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKL 398 A + Y D R + + A K T A + ++ Sbjct: 298 A-------AVATARATYLDAARRRDQGRPYSQQASIA-----KLTATDAAMKVTTDAVQV 345 Query: 399 CGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 GG GY + +EG N + +L +AR L + Sbjct: 346 FGGVGYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLTR 387 >2IX5-A nrPDB Length = 436 Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats. Identities = 74/341 (21%), Positives = 126/341 (36%), Gaps = 53/341 (15%) Query: 96 PAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATF 155 ++ +H + + I G+E Q++K+L ++ + C+A TE +GS+ GL TTAT Sbjct: 133 STFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK 192 Query: 156 DPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHS 215 V K W G + +++AR T + I+GFIV+ Sbjct: 193 -------VEGGWKINGQKRWIGN-STFADLLIIFARNTTTNQ---INGFIVK-------K 234 Query: 216 PLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQ 275 P + I K+G + NG ++ +V +P + L ++ D K Sbjct: 235 DAPGLKATKIPNKIGL---RMVQNGDILLQNVFVPDEDRLPGVNSF--------QDTSKV 283 Query: 276 LVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLF 335 L R + + RY R+QFGA + ++ Q +L Sbjct: 284 LAVS-----RVMVAWQPIGISMGIYDMCHRYLKERKQFGA-------PLAAFQLNQQKLV 331 Query: 336 PLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEEC 395 +L + A +G L LY + K+ ++ + Sbjct: 332 QMLGNVQAMFLMGWRLCKLYETGQMTPGQASLG------------KAWISSKARETASLG 379 Query: 396 RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 R+L GG+G L + + F P TYEG + L R Sbjct: 380 RELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 >2JIF-A nrPDB Length = 404 Score = 230 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 63/341 (18%), Positives = 120/341 (35%), Gaps = 50/341 (14%) Query: 98 YVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDP 157 + ++ + I+ GTEEQ+ +L + +G + +E G GS+ L+T A D Sbjct: 110 FCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFCLSEAGAGSDSFALKTRA--DK 166 Query: 158 KTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPL 217 + D +V++ SK W + +V A + GI F+V Sbjct: 167 EGDYYVLN-----GSKMWISSAEH-AGLFLVMANVDPTIGYKGITSFLVDR-------DT 213 Query: 218 PNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLV 277 P + +G K+G A ++ L F++V++P +L ++ + Sbjct: 214 PGLHIGKPENKLGLRASST---CPLTFENVKVPEANILGQIG------------HGYKYA 258 Query: 278 YGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL 337 G++ R I A Y R QFG ++ D++ Q+++ + Sbjct: 259 IGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFG-------KRLFDFQGLQHQVAHV 311 Query: 338 LASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRK 397 A R + L + + A K + +C + Sbjct: 312 ATQLEAARLLTYNAARLLEAGKPFIKEASMA------------KYYASEIAGQTTSKCIE 359 Query: 398 LCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 GG GY + + F YEG + + +A+ + Sbjct: 360 WMGGVGYTKDYPVEKYFRDAKIGTIYEGASNIQLNTIAKHI 400 >3SF6-A nrPDB Length = 403 Score = 228 bits (580), Expect = 8e-60, Method: Composition-based stats. Identities = 74/342 (21%), Positives = 114/342 (33%), Gaps = 55/342 (16%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 + V + + + AI G++EQ+ +WL IGC+ TE HGS+ G+ T AT Sbjct: 110 SLVSVQGSLAMYAIHAFGSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATR- 168 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 D++++ T +K W G V+ AVV+AR GI GF+V + Sbjct: 169 -SGDDWIL-----TGTKMWITN-GSVADVAVVWARTD-----EGIRGFVVP-------TD 209 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P T I +KM A + + L+ D VR+P L P Sbjct: 210 TPGFTANTIKSKMSLRASVTSE---LVLDGVRLPDSARL-------------PGATSLGA 253 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 + R IV A A + A Y+ R QF GG ++ Q +L Sbjct: 254 PLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGG-------FQLTQQKLAD 306 Query: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECR 396 + + L L + R Sbjct: 307 MTLEYGKGFLLALHLGRQKDAGELAPEQVSLGKLNNVR------------EAIEIARTAR 354 Query: 397 KLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 + G G + TYEG + + L + + L Sbjct: 355 TVLGASGITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQAL 396 >4KTO-A nrPDB Length = 410 Score = 226 bits (575), Expect = 3e-59, Method: Composition-based stats. Identities = 67/337 (19%), Positives = 118/337 (35%), Gaps = 49/337 (14%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H + V I G Q+ ++L + +G A +E G GS+V ++ A D + D Sbjct: 118 HSNLCVNQINRNGKPAQKSRYLPKLISGEHVGALAMSEPGAGSDVVSMKLKA--DKRGDR 175 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 +V++ SK W G + VVYA+ GI F+V+ P + Sbjct: 176 YVLN-----GSKMWITN-GPDADVLVVYAKTDPAAGPRGITAFLVE-------KAFPGFS 222 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 G K+G N+ + L+F +P + +L + GE V +++ + Sbjct: 223 AGQKLDKLGMRGSNTSE---LIFTDCEVPEENVLGGV------GEGV------KVLMSGL 267 Query: 282 VYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASA 341 Y R + A ++ + + Y R+QFG G +++ Q +L + + Sbjct: 268 DYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIG-------EFQLMQGKLADMYVT- 319 Query: 342 YAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGG 401 + V AA D A L E + GG Sbjct: 320 ---------MNAARAYVYAVAAACDRGETARKDAAGCIL--YAAEKATAMALEAIQALGG 368 Query: 402 HGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 +GY L G + + ++ + R L Sbjct: 369 NGYTNDYPAGRLLRDAKLYEIGAGTSEIRRMLIGREL 405 >3MPI-A nrPDB Length = 397 Score = 224 bits (571), Expect = 9e-59, Method: Composition-based stats. Identities = 62/368 (16%), Positives = 131/368 (35%), Gaps = 58/368 (15%) Query: 78 ELRLNEEEAGRLRHFI--DQPAY----VDLHWGM----FVPAIKGQGTEEQQKKWLSLAN 127 E + G L I ++ A + + M I G+E +KK++ + Sbjct: 59 EYGGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLS 118 Query: 128 KMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAV 187 + +G + TE GS+V + +TA + K D ++++ SK W + + + Sbjct: 119 SAEFLGGFGITEPDAGSDVMAMSSTA--EDKGDHWLLN-----GSKTWISNAAQ-ADVLI 170 Query: 188 VYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHV 247 YA G+ F+++ R+ P I ++ ++ G L D+V Sbjct: 171 YYAYTDKAAGSRGLSAFVIEPRN------FPGIKTSNLEK----LGSHASPTGELFLDNV 220 Query: 248 RIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYS 307 ++P++ +L + ++V+G++ + R + A + A +Y Sbjct: 221 KVPKENILGK------------PGDGARIVFGSLNHTRLSAAAGGVGLAQACLDAAIKYC 268 Query: 308 AVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDF 367 RRQFG + D++ Q+ + + A R + + RL Sbjct: 269 NERRQFG-------KPIGDFQMNQDMIAQMAVEVEAARLLAYKAAAAKDE--GRLNNGLD 319 Query: 368 ATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDN 427 + + A A + ++ G +GY + + EG Sbjct: 320 VAMAKYAA---------GEAVSKCANYAMRILGAYGYSTEYPVARFYRDAPTYYMVEGSA 370 Query: 428 VVLQLQVA 435 + ++ +A Sbjct: 371 NICKMIIA 378 >6ES9-A nrPDB Length = 551 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 73/351 (20%), Positives = 120/351 (34%), Gaps = 42/351 (11%) Query: 90 RHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGL 149 R +I + + + I GTE Q+ KWL +I+ TE GS++ L Sbjct: 241 RGYIGVGS-LGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSL 299 Query: 150 ETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDY-GIHGFIVQL 208 T A D +++V+ T +K W + + + AR D+ G+ F+ + Sbjct: 300 RTRAVRD--GEDWVV-----TGNKTWITH-AQRTHVMTLLARTDPETTDWRGLSMFLAEK 351 Query: 209 RSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYV 268 D P P T G G ++ Y M L FD RI + +L Sbjct: 352 EPGTDDDPFP--TPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLG----------GE 399 Query: 269 PSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYK 328 P KQL T R A A A I RY+ R+QFG +I++ Sbjct: 400 PGRGFKQL-METFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKS-------LIEFP 451 Query: 329 TQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTAT 388 ++L + R + + W + A K L Sbjct: 452 RVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMA------------KLLGARVA 499 Query: 389 ADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM 439 + ++ GG+G+ + + +EG + +AR L+ Sbjct: 500 WAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLL 550 >1SIR-A nrPDB Length = 394 Score = 218 bits (555), Expect = 5e-57, Method: Composition-based stats. Identities = 67/345 (19%), Positives = 126/345 (36%), Gaps = 52/345 (15%) Query: 94 DQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTA 153 + + + + + I G+EEQ++K+L K +++GC+ TE GS+ +ET A Sbjct: 92 GYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRA 151 Query: 154 TFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLED 213 ++ + ++ +K W ++ VV+AR +D I GF+++ Sbjct: 152 HYNSSNKSYTLN-----GTKTWITN-SPMADLFVVWARC----EDGCIRGFLLE------ 195 Query: 214 HSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVP 273 + ++ I K A + G ++ D V +P + +L S + Sbjct: 196 -KGMRGLSAPRIQGKFSLRASAT---GMIIMDGVEVPEENVLPGASSLGG---------- 241 Query: 274 KQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNR 333 +G + R I A + A +Y+ R QFG + + Q + Sbjct: 242 ---PFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFG-------VPLARNQLIQKK 291 Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 L +L L L AA + +L + + C L D Sbjct: 292 LADMLTEITLGLHACLQLGRLKDQ---DKAAPEMVSLLKRNNCGKAL---------DIAR 339 Query: 394 ECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 + R + GG+G + TYEG + + L + R + Sbjct: 340 QARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 384 >4O5M-A nrPDB Length = 390 Score = 218 bits (554), Expect = 8e-57, Method: Composition-based stats. Identities = 60/340 (17%), Positives = 118/340 (34%), Gaps = 49/340 (14%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H + V I G+ EQ+ K+L + +G A +E G GS+V ++ A + + D Sbjct: 98 HSNLCVNQITRNGSPEQRAKYLPKLISGEHVGALAMSEPGAGSDVVSMKLAA--EKRGDR 155 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 +V++ +K W G + VVYA+ + GI FI++ + Sbjct: 156 YVLN-----GNKMWITN-GPDADVLVVYAKTDLSAGPRGISAFIIE-------KGFKGFS 202 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 K+G N+ L+F+ +P + +L EG+ V ++ + Sbjct: 203 TAQKLDKLGMRGSNT---CELVFEDCEVPAENLL------GTEGKGV------NVLMSGL 247 Query: 282 VYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASA 341 Y R + ++ + + Y R+QF G +++ Q +L + + Sbjct: 248 DYERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIG-------EFQLMQCKLADMYVTF 300 Query: 342 YAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGG 401 A R + + AG + + + GG Sbjct: 301 NASRAYVYAVAAACDRGETTRKDA------------AGCILYSAENATQMALQAIQSLGG 348 Query: 402 HGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKT 441 +GY+ L G + + ++ + R L + Sbjct: 349 NGYINDYPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFQE 388 >2PG0-A nrPDB Length = 385 Score = 217 bits (551), Expect = 2e-56, Method: Composition-based stats. Identities = 69/342 (20%), Positives = 118/342 (34%), Gaps = 51/342 (14%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 + LH + P I GTEEQ++KWL ++I A TE G GS++ + TTA D Sbjct: 91 IGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIAMTEPGAGSDLANISTTAVKD-- 148 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLIT--NGKDYGIHGFIVQLRSLEDHSP 216 D ++++ K + + VV + GI +V+ Sbjct: 149 GDYYIVN-----GQKTFITNGIH-ADLIVVACKTDPQAKPPHRGISLLVVER-------D 195 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P T G K+G ++ D L F ++P +L K Sbjct: 196 TPGFTRGRKLEKVGL---HAQDTAELFFQDAKVPAYNLLGEEGK------------GFYY 240 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 + + R + A A + +Y R FG +V +++T Q RL Sbjct: 241 LMEKLQQERLVVAIAAQTAAEVMFSLTKQYVKQRTAFG-------KRVSEFQTVQFRLAE 293 Query: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECR 396 + R + + + + + A K T E Sbjct: 294 MATEIALGRTFVDRVIEEHMAGKQIVTEVSMA------------KWWITEMAKRVAAEAM 341 Query: 397 KLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 +L GG+GY+ + + + Y G N +++ +AR L Sbjct: 342 QLHGGYGYMEEYEIARRYRDIPVSAIYAGTNEMMKTIIARQL 383 >3SWO-A nrPDB Length = 399 Score = 213 bits (543), Expect = 1e-55, Method: Composition-based stats. Identities = 70/342 (20%), Positives = 116/342 (33%), Gaps = 55/342 (16%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFD 156 ++V + + + +I G+EEQ+ +WL IGC+ TE GSN G+ T A D Sbjct: 105 SFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRD 164 Query: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 +++++ +K W G ++ A V+A+ GI GF+V + Sbjct: 165 --GSDWILN-----GTKMWITN-GNLADVATVWAQTDD-----GIRGFLVP-------TD 204 Query: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 P T +I K+ A + + L+ D+VR+P L P Sbjct: 205 TPGFTANEIHRKLSLRASVTSE---LVLDNVRLPASAQL-------------PLAEGLSA 248 Query: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 + R IV A A ++ Y+ R F + + +Y+ Q +L Sbjct: 249 PLSCLNEARFGIVFGALGAARDSLETTIAYTQSREVF-------DKPLSNYQLTQEKLAN 301 Query: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECR 396 + + L + R L ECR Sbjct: 302 MTVELGKGMLLAIHLGRIKDAEGVRPEQISLGKLNNVR------------EAIAIARECR 349 Query: 397 KLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 L GG G TYEG + + L + + L Sbjct: 350 TLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLLSIGKAL 391 >3GNC-A nrPDB Length = 399 Score = 213 bits (541), Expect = 2e-55, Method: Composition-based stats. Identities = 69/346 (19%), Positives = 124/346 (35%), Gaps = 57/346 (16%) Query: 94 DQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTA 153 + + + + + I G++ Q++K+L + IGC+ TE HGS+ + T A Sbjct: 99 GYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRA 158 Query: 154 TFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLED 213 P + + SK W ++ VV+A+L +G+D I GFI++ Sbjct: 159 RKVPGG-------YSLSGSKMWITN-SPIADVFVVWAKLDEDGRDE-IRGFILE------ 203 Query: 214 HSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVP 273 ++ I K+G A + G ++ D +P + +L + Sbjct: 204 -KGCKGLSAPAIHGKVGLRASIT---GEIVLDEAFVPEENILPHVK-------------G 246 Query: 274 KQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFG---AHNGGIETQVIDYKTQ 330 + + + R I A A IA +Y R+QFG A N I+ ++ D +T+ Sbjct: 247 LRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTE 306 Query: 331 QNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATAD 390 + + G A T+ +K + D Sbjct: 307 ITLGLQGVLRLGRMKDEG----------------------TAAVEITSIMKRNSCGKALD 344 Query: 391 GIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 R + GG+G G+ TYEG + + L + R Sbjct: 345 IARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGR 390 >4IV6-A nrPDB Length = 388 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 80/411 (19%), Positives = 136/411 (33%), Gaps = 82/411 (19%) Query: 59 KELFKSTLRKCAHAFKRIIELRLNEEEAGRL---------RHFIDQPAYVDLHWGMFVP- 108 ++ K +R+ HA EL +E G + P YV + + Sbjct: 23 EKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAVSMPCYVQVAEELARGW 82 Query: 109 ---------------AIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTA 153 + GTEEQ++K+L ++ A TE G GS++Q + T A Sbjct: 83 MSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRATMALTEPGGGSDLQAMRTVA 142 Query: 154 TFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGK--DYGIHGFIVQLRSL 211 D D++VI+ SK W + S + + + + G+ +V+ Sbjct: 143 RRD--GDDYVIN-----GSKTWISN-ARRSDLVALMCKTDPDAQPAHKGVSILLVEK--- 191 Query: 212 EDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSD 271 +P V K+G Y +++ L F R+P +L EG Sbjct: 192 -----VPGFDVSRDLPKLG---YKGVESCELNFTDARVPVSSLLG-----DDEGRGFAQ- 237 Query: 272 VPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAH---NGGIETQVIDYK 328 + + R + A A+ A A RYS R FG + + + D Sbjct: 238 -----MMKGLEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMG 292 Query: 329 TQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTAT 388 T+ LL SA E+ A + A K + Sbjct: 293 TKLYAARSLLLSAA-----------------EKFDAGQRCDMEAGMA-----KLFASETA 330 Query: 389 ADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM 439 + ++ GG+GY + F EG N + + +A+ L+ Sbjct: 331 MQIALDAVRVHGGYGYSTEYDVERYFRDAPLMIVGEGTNEIQRNVIAKQLV 381 >2CX9-A nrPDB Length = 387 Score = 209 bits (531), Expect = 3e-54, Method: Composition-based stats. Identities = 75/348 (21%), Positives = 122/348 (35%), Gaps = 53/348 (15%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 V H + I G+E Q++ +L + +G + TE G GS+ L+T A Sbjct: 89 VASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLTEPGSGSDAAALKTKAEKVEG 148 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNG----KDYGIHGFIVQLRSLEDH 214 + ++ Q ++ G V+ VV AR K GI F Sbjct: 149 G--WRLNGTKQFITQ------GSVAGVYVVMARTDPPPSPERKHQGISAF-------AFF 193 Query: 215 SPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPK 274 P + VG K+G A D L+ + + +P + +L K + Sbjct: 194 RPERGLKVGRKEEKLGLTAS---DTAQLILEDLFVPEEALLGERGKGFYD---------- 240 Query: 275 QLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRL 334 V + R I A A A+ A Y+ R FG + +++ +L Sbjct: 241 --VLRVLDGGRIGIAAMAVGLGQAALDYALAYAKGREAFGR-------PIAEFEGVSFKL 291 Query: 335 FPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEE 394 A R LY E A TL A A K + A +E Sbjct: 292 AEAATELEAARL-------LYLKAAELKDAGRPFTLEAAQA-----KLFASEAAVKACDE 339 Query: 395 CRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTV 442 ++ GG+GY+ + + EG + +L+L +AR L++ V Sbjct: 340 AIQILGGYGYVKDYPVERYWRDARLTRIGEGTSEILKLVIARRLLEAV 387 >1IVH-A nrPDB Length = 394 Score = 208 bits (528), Expect = 8e-54, Method: Composition-based stats. Identities = 58/355 (16%), Positives = 116/355 (32%), Gaps = 53/355 (14%) Query: 84 EEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHG 143 EE R + H + + + G E Q++K+L + IG A +E G Sbjct: 84 EEISRASGAVGLS--YGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAG 141 Query: 144 SNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITN--GKDYGI 201 S+V ++ A + K + ++++ +K+W G + +VYA+ GI Sbjct: 142 SDVVSMKLKA--EKKGNHYILN-----GNKFWITN-GPDADVLIVYAKTDLAAVPASRGI 193 Query: 202 HGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKV 261 FIV+ +P + K+G N+ L+F+ +IP +L +K Sbjct: 194 TAFIVE-------KGMPGFSTSKKLDKLGMRGSNT---CELIFEDCKIPAANILGHENK- 242 Query: 262 TREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIE 321 ++ + R + + + Y VR FG Sbjct: 243 -----------GVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQ------ 285 Query: 322 TQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLK 381 ++ ++ Q ++ + A R + + AG+ Sbjct: 286 -KIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHC------------TAKDCAGVI 332 Query: 382 SLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 + + + GG+GY+ + G + V +L + R Sbjct: 333 LYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGR 387 >4W9U-A nrPDB Length = 395 Score = 196 bits (497), Expect = 3e-50, Method: Composition-based stats. Identities = 65/346 (18%), Positives = 118/346 (34%), Gaps = 58/346 (16%) Query: 94 DQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTA 153 + + + + + I G++EQ+KK+L ++IGC+ TE GS+ G++T A Sbjct: 96 GYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLVSGELIGCFGLTEPDAGSDPAGMKTRA 155 Query: 154 TFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLED 213 E + + SK W ++ VV+A+ D I GFI++ Sbjct: 156 -------EKIDGGYRLSGSKMWISN-SPIADVFVVWAKS--AAHDNAIRGFILE------ 199 Query: 214 HSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVP 273 + ++ IG K+ A + G ++ D V + D +L P+ Sbjct: 200 -KGMKGLSAPKIGGKLSLRASIT---GEIVMDGVEVSEDAIL-------------PNVSG 242 Query: 274 KQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGI---ETQVIDYKTQ 330 + +G + R I A A +Y R+QF G + ++ D +T+ Sbjct: 243 LKGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQTE 302 Query: 331 QNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATAD 390 G+ + + +K D Sbjct: 303 IALGIQASLRVGRLFDEGKMAPEMI----------------------SIVKRNNCGKALD 340 Query: 391 GIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 + R + GG+G + TYEG + V L + R Sbjct: 341 IARQARDMHGGNGIQIEYHVMRHAQNLETVNTYEGTHDVHALILGR 386 >2EBA-A nrPDB Length = 385 Score = 195 bits (495), Expect = 6e-50, Method: Composition-based stats. Identities = 66/341 (19%), Positives = 119/341 (34%), Gaps = 55/341 (16%) Query: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNV-QGLETTATF 155 ++V + + + I G+EEQ++++L + +++GC+ TE GS+ ++T A Sbjct: 91 SFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFGLTEPDGGSDPYGNMKTRARR 150 Query: 156 DPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHS 215 + D +V++ +K W G ++ AV++A+ G+ G F+V + Sbjct: 151 E--GDTWVLN-----GTKMWITN-GNLAHLAVIWAK-DEGGEVLG---FLVP-------T 191 Query: 216 PLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQ 275 P ++ KM A + + L+ + VR+P L P + + Sbjct: 192 DTPGFQAREVKRKMSLRASVTSE---LVLEEVRVPESLRL-------------PKALGLK 235 Query: 276 LVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLF 335 + R I A AL A ++ R FG + + Q +L Sbjct: 236 APLSCLTQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGE-------PLAKKQLVQAKLA 288 Query: 336 PLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEEC 395 +LA W D L A A +++ Sbjct: 289 EMLA----------WHTEGLLLAWRLARLKDEGKLTPAQVSLAKRQNV--WKALQAARMA 336 Query: 396 RKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 R + GG G TYEG + V L + R Sbjct: 337 RDILGGSGITLEYHAIRHMLNLETVYTYEGTHDVHTLVLGR 377 >3R7K-A nrPDB Length = 403 Score = 179 bits (454), Expect = 3e-45, Method: Composition-based stats. Identities = 64/333 (19%), Positives = 113/333 (33%), Gaps = 50/333 (15%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 G+ +P I G++ ++++ ++IG TE G GS+V L T A + D +V Sbjct: 117 GIALPHIAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDVANLRTRAVRE--GDTYV 174 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 ++ + G + R G+ ++ S P V Sbjct: 175 VNGAKTFIT------SGVRADFVTTAVRTG-GPGYGGVSLLVIDKNS-------PGFEVS 220 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 KMG + D L F VR+P D ++ + Q+ Sbjct: 221 RRLDKMG---WRCSDTAELSFVDVRVPADNLV-----------GAENSGFLQI-MQQFQA 265 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYA 343 R I A RA+ +A ++ R FG G Q+I +K + +A Y Sbjct: 266 ERLGIAVQAYATAGRALDLAKSWARERETFGRPLTG--RQIIRHKLAEMARQVDVACTYT 323 Query: 344 FRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHG 403 + WL DV ++ + K+ A + E ++ GG G Sbjct: 324 RAVMQRWLA--GEDVVAEVSMA---------------KNTAVYACDYVVNEAVQIFGGMG 366 Query: 404 YLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 Y+ S + + G N ++ +A+ Sbjct: 367 YMRESEIERHYRDCRILGIGGGTNEIMNEVIAK 399 >3P4T-A nrPDB Length = 403 Score = 172 bits (435), Expect = 4e-43, Method: Composition-based stats. Identities = 67/335 (20%), Positives = 106/335 (31%), Gaps = 49/335 (14%) Query: 104 GMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFV 163 G+ VP + G + ++ + + IG A TE G GS+V L T A D D +V Sbjct: 114 GIAVPHMIASGDQRLIDTYVRPTLRGEKIGALAITEPGGGSDVGHLRTRA--DLDGDHYV 171 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 I+ + G + + V AR G+ +V P V Sbjct: 172 INGAKTYIT------SGVRADYVVTAARTG-GPGAGGVSLIVVD-------KGTPGFEVT 217 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 KMG + S D L + VR+P ++ + Q+ V Sbjct: 218 RKLDKMG---WRSSDTAELSYTDVRVPVANLVGSEN-----------TGFAQIA-AAFVA 262 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYA 343 R + A R + + + R FG +I + QN L + Sbjct: 263 ERVGLATQAYAGAQRCLDLTVEWCRNRDTFGR-------PLISRQAVQNTLAGMARRIDV 315 Query: 344 FRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHG 403 R V ER A + + E K+ A + +L GG G Sbjct: 316 ARVYTRH-------VVERQLAGETNLIAEV----CFAKNTAVEAGEWVANQAVQLFGGMG 364 Query: 404 YLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 Y+ S + + G +L A+ L Sbjct: 365 YMAESEVERQYRDMRILGIGGGTTEILTSLAAKTL 399 >5ZW7-A nrPDB Length = 402 Score = 166 bits (419), Expect = 4e-41, Method: Composition-based stats. Identities = 56/340 (16%), Positives = 119/340 (35%), Gaps = 55/340 (16%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H V + G+ E + K+L ++I A TE GS++ ++ TA Sbjct: 92 HLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEGG-- 149 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 ++++ + ++ ++YA+ + G+ F+++ P + Sbjct: 150 YILNGKKIFITN------APIADVFIIYAKTNPDHGFLGVSAFLIE-------KGTPGLN 196 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 VG++ K ++ ++F+ + IP+ Q + + + +M Sbjct: 197 VGEVIPK---DCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGA------------IFHDSM 241 Query: 282 VYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIET---QVIDYKTQQNRLFPLL 338 ++ + + A L+R + Y+ R+QFG G ++ ++ID K + L Sbjct: 242 IWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLR-------L 294 Query: 339 ASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKL 398 + W D +A S K L + + + Sbjct: 295 EQCRLMLYRACWKHDQGQDAEADIAMS---------------KLLISEYAVQSGLDAIQT 339 Query: 399 CGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFL 438 GG GL +P+ + G N + + +AR L Sbjct: 340 FGGAAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKL 379 >6CY8-B nrPDB Length = 380 Score = 161 bits (408), Expect = 7e-40, Method: Composition-based stats. Identities = 58/333 (17%), Positives = 113/333 (33%), Gaps = 49/333 (14%) Query: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDE 161 H I G+E + + L + I A +E GS++ L TTA + D Sbjct: 90 HTFACSMPILEHGSETLKHQLLPDLATGRKIAANAISEASAGSDISNLATTAQ--KEGDY 147 Query: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 +V++ + G ++ + VVYA G F+V P I+ Sbjct: 148 YVLNGGKSYVTN------GSIADYYVVYATTNKKHGYLGQTAFVVPRN-------TPGIS 194 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 VG+ K+G S + FD+ I +D L R EG+ ++ +M Sbjct: 195 VGNDYHKLGL---RSAPLNQVFFDNCTIHKDYALGR------EGQGA------RIFAASM 239 Query: 282 VYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASA 341 + R + A A+ R + Y+ R Q + ++ +R+ + Sbjct: 240 DWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKT-------ISRFQAVSHRIADMGVRL 292 Query: 342 YAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGG 401 + R + + W + + A + L + A + ++ G Sbjct: 293 ESARLMLYYAAWQKSQDVDNTKAVAMSKLA------------ISEAFVQSGIDSIRVHGA 340 Query: 402 HGYLWCSGLPELFAVYVPACTYEGDNVVLQLQV 434 GYL + + + + G + + + + Sbjct: 341 LGYLDEGRVNNSIKDALGSVLFSGTSDIQRELI 373 >5AHS-A nrPDB Length = 401 Score = 151 bits (382), Expect = 7e-37, Method: Composition-based stats. Identities = 68/366 (18%), Positives = 114/366 (31%), Gaps = 59/366 (16%) Query: 97 AYVDLHWGMF-VPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATF 155 + + + + AI G+EEQ K L +E GS + T A Sbjct: 83 GRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDK-PAICISEPNAGSAASEMTTRA-- 139 Query: 156 DPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHS 215 D D ++++ K+W G G H +++AR+ +G + GI FI ++ D Sbjct: 140 DKNGDHYILN-----GEKYWITGGGVSKLH-LIFARVFDDGVEQGIGAFI----TVLDDH 189 Query: 216 PLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQ 275 + VG MG + L F ++I + M+ + R Sbjct: 190 GPEGLKVGRRLYAMGVRG---IPETHLEFHDLKIHKSMMITFPDGLKR---------GFA 237 Query: 276 LVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHN---GGIETQVIDYKTQQN 332 + R A A A Y R QFG G++ V D Q Sbjct: 238 ALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLE 297 Query: 333 RLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGI 392 +L SA ++ F + +A A K Sbjct: 298 AARLMLRSAA-------------------VSGETFPDINKA----AQAKIFAAETANKVT 334 Query: 393 EECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPV 452 + + G GY + + G +L+ QVA +++ K+P Sbjct: 335 NDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVA-------SKILDMKLPQ 387 Query: 453 GTTAYM 458 Y+ Sbjct: 388 TRDGYL 393 >4HR3-A nrPDB Length = 415 Score = 148 bits (372), Expect = 1e-35, Method: Composition-based stats. Identities = 67/336 (19%), Positives = 111/336 (33%), Gaps = 53/336 (15%) Query: 107 VPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELG-HGSNVQGLETTATFDPKTDEFVIH 165 + + G++EQ++ WL + I + TE S+ + TA + DE VI+ Sbjct: 118 MEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVE--GDEVVIN 175 Query: 166 TPTQTASKWWPGGLGKVSTHAVVY-ARLITNGKDYGIHGFI-VQLRSLEDHSPLPNITVG 223 KWW G+G +++ N Y H + V + P ITV Sbjct: 176 -----GRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPM-------DTPGITVE 223 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 + MG +G + FD+VR+P D + K ++ G + Sbjct: 224 RMLPTMGFYDEPG-GHGVVSFDNVRLPADAFIAGPGK------------GFEIAQGRLGP 270 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAH---NGGIETQVIDYKTQQNRLFPLLAS 340 R A+ A R R FG GG ++ D + N+ L+ Sbjct: 271 GRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLH 330 Query: 341 AYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCG 400 A WL D + A + + +K I+ ++ G Sbjct: 331 A----------AWLL----------DTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHG 370 Query: 401 GHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVAR 436 G G L + +G + V + VAR Sbjct: 371 GGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVAR 406 >2WBI-A nrPDB Length = 428 Score = 142 bits (358), Expect = 4e-34, Method: Composition-based stats. Identities = 56/348 (16%), Positives = 115/348 (33%), Gaps = 47/348 (13%) Query: 107 VPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELG-HGSNVQGLETTATFDPKTDEFVIH 165 + + G+EEQ+K+WL + I C+ TE S+ +E + D D +VI+ Sbjct: 124 MEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDE--DSYVIN 181 Query: 166 TPTQTASKWWPGGLG-KVSTHAVVYARLITN--GKDYGIHGFIVQLRSLEDHSPLPNITV 222 KWW G G A+V R + +V + P + + Sbjct: 182 -----GKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMN-------TPGVKI 229 Query: 223 GDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMV 282 + G + + F+ VR+P +++ + ++ G + Sbjct: 230 IRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEGR------------GFEISQGRLG 277 Query: 283 YVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAY 342 R RA+ I + R F + ++ ++ + + + Sbjct: 278 PGRIHHCMRTVGLAERALQIMCERATQRIAF-------KKKLYAHEVVAHWIAESRIAIE 330 Query: 343 AFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGH 402 R + + D A A +K A + ++ ++CGG Sbjct: 331 KIRLLTLKAAH----------SMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGA 380 Query: 403 GYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKV 450 G L ++A+ +G + V +A ++ A+ + K+ Sbjct: 381 GVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTAKI 428 >4X28-A nrPDB Length = 400 Score = 123 bits (308), Expect = 3e-28, Method: Composition-based stats. Identities = 56/341 (16%), Positives = 107/341 (31%), Gaps = 62/341 (18%) Query: 107 VPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHT 166 P I GT+EQ++ +L + +E G G+++ L TTA D D++V++ Sbjct: 99 APTIMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTAVRD--GDDYVVN- 155 Query: 167 PTQTASKWWPGGLGKVSTHAVVYARLITN----GKDYGIHGFIVQLRSLEDHSPLPNITV 222 K W L + + + + R K GI IV + + Sbjct: 156 ----GQKMW-TSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVP-------TTAEGFSW 203 Query: 223 GDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMV 282 + T G D + VR+P + + +LV + Sbjct: 204 TPVHTMAGP------DTSATYYSDVRVPVANRVGE------------ENAGWKLVTNQLN 245 Query: 283 YVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAY 342 + R +V+ A + ++ + G T++ID + Q L + A A Sbjct: 246 HERVALVSPAPIF--GCLREVREWAQNTKDAGG------TRLIDSEWVQLNLARVHAKAE 297 Query: 343 AFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGH 402 + + L + + D P A + K T + ++ G Sbjct: 298 VLKLINWELA------SSQSGPKDAGPSP---ADASAAKVFGTELATEAYRLLMEVLGTA 348 Query: 403 GYLWCSG--------LPELFAVYVPACTYEGDNVVLQLQVA 435 L + + + + G N V + + Sbjct: 349 ATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIG 389 >1R2J-A nrPDB Length = 366 Score = 118 bits (295), Expect = 9e-27, Method: Composition-based stats. Identities = 67/411 (16%), Positives = 119/411 (28%), Gaps = 58/411 (14%) Query: 35 SDRIARLVASDPVFEKSNRARLSRKELFKSTLRK--CAHAFKRIIELRLNEEEAGRLRHF 92 D + + D E L R L + CA L L E G Sbjct: 4 RDALLTDLVGDRAAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAH 63 Query: 93 IDQPAY----VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQG 148 + V GM ++ G Q+ +L + +E GS++ Sbjct: 64 VGSLCSSLRSVMTSQGMAAWTVQRLGDAGQRATFLKELTSG-KLAAVGFSERQAGSDLSA 122 Query: 149 LETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQL 208 + T D D V+ + + H VV+ ++ G +V Sbjct: 123 MRTRVRLD--GDTAVVDGHKVWTT------AAAYADHLVVF-----GLQEDGSGAVVV-- 167 Query: 209 RSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYV 268 + P + V + G A D L D VR+P +L G Sbjct: 168 ----VPADTPGVRVERVPKPSGCRAAGHAD---LHLDQVRVPAGAVLA--------GSGA 212 Query: 269 PSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYK 328 + LV ++ Y R+++ L A ++ R QFG G D++ Sbjct: 213 SLPM---LVAASLAYGRKSVAWGCVGILRACRTAAVAHARTREQFGRPLG-------DHQ 262 Query: 329 TQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTAT 388 + L + V E+ + + PE T K + Sbjct: 263 LVAGHIADLWTAEQIAARVCEYASDHWDE-----------GSPEMVPATILAKHVAAERA 311 Query: 389 ADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM 439 A G ++ G + + EG + + ++ +A+ + Sbjct: 312 AAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHAL 362 >5EZ3-A nrPDB Length = 573 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 70/384 (18%), Positives = 120/384 (31%), Gaps = 54/384 (14%) Query: 85 EAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEE-QQKKW----LSLANKMQIIGCYAQTE 139 EAG L A L M P + Q + +K+ K + TE Sbjct: 158 EAGHLCPLTMTSA--SLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTE 215 Query: 140 LGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDY 199 G++V+ T A T KW+ +S + A+ Sbjct: 216 KQGGTDVRANATRAEPAIGG------AWRLTGHKWFMS--APMSDAFLTLAQT-----KE 262 Query: 200 GIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLS 259 G+ F++ + S + K+GN + S + + FD L ++ Sbjct: 263 GLSCFLLPRLGEKGESN--GFFFQRLKDKLGNRSNASSE---VEFDGA-------LGQM- 309 Query: 260 KVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGG 319 + GE V + + + R ++ + + A +S R FG Sbjct: 310 -IGSPGEGV------KTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFG----- 357 Query: 320 IETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAG 379 +++ Q L + A G + +AASD A A + T Sbjct: 358 --KPLVEQPLMQRVLADM-----ALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPV 410 Query: 380 LKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM 439 +K + E + GG+GY+ L + +EG V+ L VAR L Sbjct: 411 VKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLS 470 Query: 440 KTVAQLGSGKVPVGTTAYMGRAAH 463 + A V + +G Sbjct: 471 RAPALFDG--VLDWISGQLGPRGQ 492 >4Y9J-A nrPDB Length = 593 Score = 109 bits (271), Expect = 6e-24, Method: Composition-based stats. Identities = 65/411 (15%), Positives = 125/411 (30%), Gaps = 60/411 (14%) Query: 109 AIKGQGTEEQQKKWLSLANKMQIIGCYA----QTELGHGSNVQGLETTATFDPKTDEFVI 164 ++ G + + + + TE GS+V G T D + + Sbjct: 158 SLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRL 217 Query: 165 HTPTQTASKWWPGGLGKVSTHAVVYARLITNGKD-----YGIHGFIVQLRSLEDHSPLPN 219 H +S + A+ AR++ + + G+ F++++R + L Sbjct: 218 HGYKWFSS-------AVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGN--LNG 268 Query: 220 ITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYG 279 I + + K+G + + L+ D ++ +G V Sbjct: 269 IQMVRLKNKLGTKQLPTAE---LLLDGA---------IAERIGDQGRGVAGIS------N 310 Query: 280 TMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLA 339 + R + + R + +A YS R FG + L + Sbjct: 311 MLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSK-------WPLHTTTLAKMEV 363 Query: 340 SAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLC 399 + L ++ A + T LK + E + Sbjct: 364 DTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRL--ITPVLKLYAGKQAVPMVSEGIECF 421 Query: 400 GGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMG 459 GG GY+ +GLP L +EG VL L V R + SGK + Sbjct: 422 GGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLR--------VFSGKE-----NILL 468 Query: 460 RAAHLLQCRSGVQKAED--WLNPDVVLEAFEARALRMAVTCAKNLSKFENQ 508 ++ G K ED +E+ + ++ V + + + E + Sbjct: 469 AFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETR 519 >3U33-A nrPDB Length = 541 Score = 102 bits (253), Expect = 6e-22, Method: Composition-based stats. Identities = 71/357 (19%), Positives = 110/357 (30%), Gaps = 50/357 (14%) Query: 123 LSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKV 182 L K ++ TE GS+V T A + KW+ Sbjct: 170 LPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDG------SYRLVGHKWFFS--VPQ 221 Query: 183 STHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFL 242 S +V A+ G+ F V + I + + K+GN S + + Sbjct: 222 SDAHLVLAQT-----AGGLSCFFVPRFLPDGQRNA--IRLERLKDKLGN---RSNASCEV 271 Query: 243 MFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCI 302 F + EGE + L G M R + + RA + Sbjct: 272 EFQDA---------IGWLLGLEGEGIR----LILKMGGM--TRFDCALGSHAMMRRAFSL 316 Query: 303 ATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERL 362 A ++ R FG N I+ ++ + + L +A FR W +R Sbjct: 317 AIYHAHQRHVFG--NPLIQQPLMRHVLSRMALQLEGQTALLFRLARAW---------DRR 365 Query: 363 AASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACT 422 A + A T K + + E ++ GG GY S LP L+ Sbjct: 366 ADAKEALWARLF--TPAAKFVICKRGMPFVAEAMEVLGGIGYCEESELPRLYREMPVNSI 423 Query: 423 YEGDNVVLQLQVARFLMKTV----AQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAE 475 +EG ++ L V R L K + G Y RA LQ + E Sbjct: 424 WEGSGNIMCLDVLRVLNKQAGVYDLLSEAFVEVKGQDRYFDRAVRRLQQQLRKPAEE 480 >4RM7-A nrPDB Length = 391 Score = 99.5 bits (246), Expect = 4e-21, Method: Composition-based stats. Identities = 47/316 (14%), Positives = 104/316 (32%), Gaps = 51/316 (16%) Query: 128 KMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAV 187 ++ A +E GS+ + + T T + D V++ +K + G+ + + Sbjct: 119 TGRLSYALAISEPEAGSDTRSMRTHVTRE--GDTLVMN-----GTKMFVNN-GEYAPALL 170 Query: 188 VYARLIT-NGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDH 246 V A T + + ++V + ++ K+G + + + FD+ Sbjct: 171 VSAYDKTGDDGEPEFSFWMVPRSAAGIYAY--------PEQKIGQ---SMLPFATVRFDN 219 Query: 247 VRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRY 306 V + L SK + +Y + Y R A A A+ A + Sbjct: 220 VEVKESWRLKGSSKGFSQ------------LYSLLEYGRVFTCAAALGEAQAAMEDAVAW 267 Query: 307 SAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASD 366 + R FG ++ D + Q +L + R + Y + Sbjct: 268 ARGREAFGQ-------RIADLQQVQMKLTEMEVKLTNMRNLVYGAAREYDRGEHKRL--- 317 Query: 367 FATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGD 426 A +K A + + ++ GG GY+ + + ++ +G Sbjct: 318 ---------SVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQDCRGYQFADGT 368 Query: 427 NVVLQLQVARFLMKTV 442 + V+ + A +++ Sbjct: 369 DEVMVVIAAPLILEQY 384 >3MKH-A nrPDB Length = 438 Score = 93.0 bits (229), Expect = 4e-19, Method: Composition-based stats. Identities = 50/348 (14%), Positives = 106/348 (30%), Gaps = 40/348 (11%) Query: 103 WGMFVPAIKGQGTEEQQKKWLSLANKMQ--IIGCYAQTELGHGSNVQ-----GLETTATF 155 G+ + I Q ++L+ + + +E G +N G +TTA Sbjct: 99 TGLGLTPINLAAGP-QHAEFLAPFLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARL 157 Query: 156 DPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYG--IHGFIVQLRSLED 213 + DE+VI+ A+ G K A V R T + G ++ + Sbjct: 158 E--GDEWVINGEKMWATNC-AGWDFKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRA 214 Query: 214 HSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVP 273 ++ + + S+ + + +VR+P +L P+ Sbjct: 215 DLDRNGEGSFEVLRHVATPGHTSVSGPHVRYTNVRVPTKNVLC------------PAGQG 262 Query: 274 KQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNR 333 ++ +G + A + A A +++ N G +++ + + Sbjct: 263 AKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKE------DNRGGAVPLLERQAFADL 316 Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 L + A R + + A L K + A Sbjct: 317 LSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAA--------KVFCSEAAVKACT 368 Query: 394 ECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNV-VLQLQVARFLMK 440 + G Y +L V ++G NV + + + + ++K Sbjct: 369 DVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGNVGIRRRHLQQLMLK 416 >4ZYJ-A nrPDB Length = 425 Score = 84.5 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 65/356 (18%), Positives = 111/356 (31%), Gaps = 54/356 (15%) Query: 65 TLRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLS 124 +L A A RI + A L + +D W P+ T + L Sbjct: 102 SLHDVALALARIA--GRDAGVALALHMQFSRGLTLDFEWRHGAPS-----TRPLAEDLLR 154 Query: 125 LANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVST 184 + + C G +V+G TT + ++ S + ++T Sbjct: 155 QMGAGEAVIC------GAVKDVRG--TTVLTRATDGSYRLNGRKTLVS------MAGIAT 200 Query: 185 HAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMF 244 H VV RL G V+L + P +TV D MG + S+D ++F Sbjct: 201 HYVVSTRLEEAGAP-------VRLAAPVVARTTPGLTVLDNWDGMGMRSSGSVD---IVF 250 Query: 245 DHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIAT 304 D + RD++L R R+ + + ++ A IA Sbjct: 251 DGCPVDRDRVLPRGEPGVRDDAALAGQTVSSIA----------MLGIYVGIAEAARRIAL 300 Query: 305 RYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAA 364 + +RR+ GA G + + + A +A + + L+ Sbjct: 301 --TELRRRGGAPAG-----------VRTTVAEIDARLFALHTAVASALTTADRLADDLSG 347 Query: 365 SDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 A K L + +++C L GG GY L L+ Sbjct: 348 DLAARGRAMMTPFQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRAG 403 >5GJ7-A nrPDB Length = 398 Score = 81.8 bits (200), Expect = 9e-16, Method: Composition-based stats. Identities = 63/417 (15%), Positives = 129/417 (30%), Gaps = 57/417 (13%) Query: 14 AEFDVEDMKIVWAGSRHAFEVSDRIARLV-ASDPVFEKSNR-ARLSRKELFKSTLRKCAH 71 A +D+ + A R ++ +A+ P +++ + ++L S + Sbjct: 3 AMYDIYGEAALPADVRERLRITRDLAQAFHERAPEHDRAGDFPFENIEDLKASGYVRWTV 62 Query: 72 AFKRIIELRLNEEEAGRLRHFI---DQPAYVDLHWGMFVPA-IKGQGT--EEQQKKWLSL 125 + L L+ EE + + D + + W + + ++ G +E + Sbjct: 63 PVEY-GGLGLSLEEMLMHQEVLAKGDGSTALAIGWHVGILLHLRETGAFPDELFRMVCES 121 Query: 126 ANKMQIIGCYAQTELGHGSNVQG--LETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVS 183 K + TE GS +G ETTA P T K + ++ Sbjct: 122 VVKEGALINSCATEPATGSPSRGGKPETTAVKVPGG-------YRITGRKTFSTLSPALT 174 Query: 184 THAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLM 243 V + + F+V+ + + + +G A S D ++ Sbjct: 175 WIMVTATVADEDV----VGQFLVRKED---------VEIVETWDTLGMRATGSHD---IV 218 Query: 244 FDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIA 303 V +P +++++ + + + E P L I A A A Sbjct: 219 LKDVFVPEERVIV-IQRPGVQAERRPDGSGWLL----------HIPACYLGIALAARDFA 267 Query: 304 TRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLA 363 Y+A R + E ++ K + L L A + D+ R Sbjct: 268 LEYAATYRPNTLPHPIAEVPHVEQKLGEMELKLLAARTLLY------------DLARRFD 315 Query: 364 ASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 A+ + +K+L T A ++ ++ GG L + Sbjct: 316 AASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGGRSLSRALPLERYYRDVRAG 372 >3M9V-A nrPDB Length = 439 Score = 78.3 bits (191), Expect = 9e-15, Method: Composition-based stats. Identities = 53/328 (16%), Positives = 92/328 (28%), Gaps = 48/328 (14%) Query: 98 YVDLHWGMFVPAIKGQGTEEQQ---KKWLSLANKMQIIGCYAQTELGHGSNVQGLETTAT 154 ++ L G+ + G E + ++ L + C + TT Sbjct: 103 HMQLSRGLTLGYEWRHGDERARTLAERILRGMVAGDAVVCSGI------KDHHTAVTTLR 156 Query: 155 FDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDH 214 D +++ S + V TH V+ AR + +V Sbjct: 157 PDGAGG-WLLSGRKTLVS------MAPVGTHFVINARTDGTDGPPRLASPVV-------T 202 Query: 215 SPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPK 274 P TV D +G A ++D ++FD IP D +LMR P Sbjct: 203 RDTPGFTVLDNWDGLGMRASGTVD---IVFDDCPIPADHVLMRD----------PVGARN 249 Query: 275 QLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRL 334 V +++ A A + RR ++ +RL Sbjct: 250 DAVLAGQTVSSVSVLGVYVGVAQAAYDTAVA-ALERRP--EPPQAAALTLVAE--IDSRL 304 Query: 335 FPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEE 394 + L A+A + + L + + + C K + + + Sbjct: 305 YALRATAGSALTAADALSADLSGDMDERGR----QMMRHFQC---AKLAVNRLAPEIVSD 357 Query: 395 CRKLCGGHGYLWCSGLPELFAVYVPACT 422 C L GG Y L L Sbjct: 358 CLSLVGGASYTAGHPLARLLRDVQAGRF 385 >3MXL-A nrPDB Length = 395 Score = 77.2 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 58/355 (16%), Positives = 100/355 (28%), Gaps = 50/355 (14%) Query: 66 LRKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSL 125 R A + + A + + + W P ++ ++ L Sbjct: 68 TRLYDVATALMRLAEADASTALAWHVQLSRGLTLTYEWQHGTPPVRAMA-----ERLLRA 122 Query: 126 ANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTH 185 + + C A + G+ T D +++ S + ++TH Sbjct: 123 MAEGEAAVCGAL------KDAPGVVTELHSDGAGG-WLLSGRKVLVS------MAPIATH 169 Query: 186 AVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFD 245 V+A+ + V L H P +TV D +G A +++ ++FD Sbjct: 170 FFVHAQRRDDDGS-------VFLAVPVVHRDAPGLTVLDNWDGLGMRASGTLE---VVFD 219 Query: 246 HVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATR 305 + D++L R R + + I A A IA Sbjct: 220 RCPVRADELLERGPVGARRDAVLAGQTVSSITM-------LGIYA---GIAQAARDIAVG 269 Query: 306 YSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAAS 365 + A R G G V T+ L + A L D ER Sbjct: 270 FCAGR--GGEPRAGARALVAGLDTRLYALRTTVG--AALTNADAASVDLSGDPDER---G 322 Query: 366 DFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 P +A K +++C L GG Y L L+ Sbjct: 323 RRMMTPFQYA-----KMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVRAG 372 >2C12-A nrPDB Length = 439 Score = 76.0 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 50/351 (14%), Positives = 104/351 (29%), Gaps = 56/351 (15%) Query: 101 LHWGMFVPAIKGQGTEEQQKKWLSLANK--MQIIGCYAQTELGHGSN-----VQGLETTA 153 + + + + + Q+K+L + + +E +N GL+TTA Sbjct: 95 VATALGLMPVILCDSPSLQEKFLKPFISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTA 154 Query: 154 TFDPKTDEFVIHTPTQTASKWWPGGLG----KVSTHAVVYARLITNG---------KDYG 200 +E+VI + K WP G K + A V R+ + Sbjct: 155 R--KVGNEWVI-----SGEKLWPSNSGGWDYKGADLACVVCRVSDDPSKPQDPNVDPATQ 207 Query: 201 IHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSK 260 I +V ++ ++ +G+ + + F +P + +L Sbjct: 208 IAVLLVTRETIANNKKDAYQILGEPE----LAGHITTSGPHTRFTEFHVPHENLLC---- 259 Query: 261 VTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGI 320 P + LV + A A A A ++ + G+ + Sbjct: 260 -------TPGLKAQGLVETAFAMSAALVGAMAIGTARAAFEEALVFAKSDTRGGSKH--- 309 Query: 321 ETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGL 380 +I++++ ++L R + D + Sbjct: 310 ---IIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQ--------T 358 Query: 381 KSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQ 431 K TT + + + K G Y P L + ++G N+ L+ Sbjct: 359 KIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIGLR 409 >4XVX-A nrPDB Length = 389 Score = 71.0 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 63/351 (17%), Positives = 112/351 (31%), Gaps = 56/351 (15%) Query: 99 VDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPK 158 V LH + ++ G + + A + + C +E GS++Q +ET Sbjct: 86 VSLHDS-AIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDG 144 Query: 159 TDEFVIHTPTQTASKWWPGGLGKVSTHAVVYAR-LITNGKDYGIHGFIVQLRSLEDHSPL 217 E K + L ++ H +V AR + + + +V + + + Sbjct: 145 GFE-------VRGVKKFVS-LSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQT 196 Query: 218 PNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLV 277 P K+G G ++ +P D ++ R + Sbjct: 197 P-------YRKVGAGPLDTAAVCI----DTWVPADALVAR-----------AGTGLAAIS 234 Query: 278 YGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPL 337 +G + + R +I + + RA+ I RRQFG + + Q R+ L Sbjct: 235 WG-LAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLL 293 Query: 338 LASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRK 397 YA + E + T A L E + I EC Sbjct: 294 ---RYALHGIAEQGR--LELRTAAAVKVTAARLGE-----------------EVISECMH 331 Query: 398 LCGGHGYLWC-SGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVAQLGS 447 + GG GYL + L + + A G + VL VA + + Sbjct: 332 IFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGMTPDHDGYAA 382 >5XDD-A nrPDB Length = 414 Score = 66.0 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 53/360 (14%), Positives = 101/360 (28%), Gaps = 48/360 (13%) Query: 71 HAFKRIIELRLNEEEAGRLRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQ 130 ++ I E+ + G L + H+ F + + EQ+ +W A + + Sbjct: 72 TVYEAIAEIASADASLGHLFGY---------HFSNFA-YVDLFASPEQKARWYPQAVRER 121 Query: 131 IIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYA 190 A +E +V TAT P + I+ +K + G + +V+A Sbjct: 122 WFLGNASSENNA--HVLDWRVTATPLPDG-SYEIN-----GTKAFCSGSAD-ADRLLVFA 172 Query: 191 RLITNGKDYG-IHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRI 249 + G I ++ S + V +G D+G + F V + Sbjct: 173 VTSRDPNGDGRIVAALIP-------SDRAGVQVNGDWDSLGM---RQTDSGSVTFSGVVV 222 Query: 250 PRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAV 309 D++L +VT +++ A+ A YS Sbjct: 223 YPDELLGTPGQVTDAFASGSKPSLWT-PITQLIFTHLY-----LGIARGALEEAAHYSRS 276 Query: 310 R-RQFGAHNGGIETQVID---YKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAAS 365 R F G+E D L + R V ++ L+ Sbjct: 277 HSRPF--TLAGVEKATEDPYVLAIYGEFAAQLQVAEAGAREVALRVQELWERNHVTPEQ- 333 Query: 366 DFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGH-GYLWCSGLPELFAVYVPACTYE 424 + A K + T + + G G + ++ Sbjct: 334 ----RGQLMVQVASAKIVATRLVIELTSRLYEAMGARAAASRQFGFDRFWRDARTHTLHD 389 >4X28-D nrPDB Length = 373 Score = 66.0 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 57/338 (16%), Positives = 93/338 (27%), Gaps = 60/338 (17%) Query: 105 MFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQT-ELGHGSNVQGLETTATFDPKTDEFV 163 + A+ G+ E Q+ W A I A E+G G VQ T Sbjct: 93 LAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGP-VQAAGTG----------- 140 Query: 164 IHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVG 223 H T ++ G G V+ +V A + G F+V + P + V Sbjct: 141 -HGYRLTGTRTQVG-YGPVADAFLVPAETDS-----GAAVFLV-------AAGDPGVAVT 186 Query: 224 DIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVY 283 + S+ G L + ++ + + G T+ Sbjct: 187 A----LATTGLGSV--GHLELNGAKVDAARRVGGTDVAVWLGT-----------LSTLSR 229 Query: 284 VRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYA 343 A L R + + Y+ R QF G ++ RL Sbjct: 230 T-----AFQLGVLERGLQMTAEYARTREQFDRPIGS-------FQAVGQRLADGYIDVKG 277 Query: 344 FRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHG 403 R W + + LA+ + + TAG A + GG G Sbjct: 278 LRLTLTQAAWRVAE--DSLASRECPQPADIDVATAGF--WAAEAGHRVAHTIVHVHGGVG 333 Query: 404 YLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKT 441 + F G ++ R L +T Sbjct: 334 VDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAET 371 >4JEK-A nrPDB Length = 453 Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 43/314 (13%), Positives = 88/314 (28%), Gaps = 26/314 (8%) Query: 107 VPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHT 166 P I+ G++EQ++ + + A +E + S+V + +AT +V++ Sbjct: 137 APMIELIGSQEQEEHLYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPTEDGG-YVLN- 192 Query: 167 PTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIG 226 +K + G V + + I + +T D Sbjct: 193 ----GTKHFCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRA-------GVTPNDDW 241 Query: 227 TKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQ 286 +G D+G F +V++ D++L + +++ Sbjct: 242 AAIGM---RQTDSGSTDFHNVKVEPDEVLGAPNAF-VLAFIQSERGSLFAPIAQLIFANV 297 Query: 287 TIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRF 346 A+ A Y+ R Q Q + + Sbjct: 298 Y-----LGIAHGALDAAREYT--RTQARPWTPAGIQQATEDPYTIRSYGEFTIALQGADA 350 Query: 347 VGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLW 406 L V ++ A E +G+K+L T A + ++ G G Sbjct: 351 AAREAAHLLQTVWDKGDALTPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHP 410 Query: 407 CSGLPELFAVYVPA 420 G + Sbjct: 411 RYGFDRFWRNVRTH 424 >5LVW-A nrPDB Length = 413 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 46/271 (16%), Positives = 78/271 (28%), Gaps = 38/271 (14%) Query: 152 TATFDPKTDEFVIHTPTQTASKWWPGGLGKV-STHAVVYAR-LITNGKDYGIHGFIVQLR 209 TA P T S WP G G + A++ AR + +G+ G +V R Sbjct: 144 TAVRTPGG-------YRLTGS--WPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPAR 194 Query: 210 SLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREG--EY 267 +TV D +G A S ++ +P +++ + +RE + Sbjct: 195 D---------LTVEDTWHTVGMRATGS---HTVVLRDTFVPEHRVISGELQRSRESATDL 242 Query: 268 VPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDY 327 + + M V ++V A A V A GI Sbjct: 243 GLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEK-----------APTRGIAPSKYTR 291 Query: 328 KTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHAC-TAGLKSLTTT 386 +T L A + AA D LP++ G + Sbjct: 292 QTDSRTFVSSLGRT-ALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVS 350 Query: 387 ATADGIEECRKLCGGHGYLWCSGLPELFAVY 417 ++E G + + L + Sbjct: 351 LVTTALDELLWAHGAASFAESNPLQRYWRDA 381 >2JBS-A nrPDB Length = 422 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 41/281 (14%), Positives = 73/281 (25%), Gaps = 28/281 (9%) Query: 163 VIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGF-IVQLRSLEDHSPLPNIT 221 V W G V + R +G I+ F ++ E Sbjct: 157 VEGGIILNGDYGWSSGCDHAEYAIVGFNRFDADGNK--IYSFGVIPRSDYEIVDNWYAQA 214 Query: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 + G+KM L +V IP ++ + + ++ Y Sbjct: 215 IKSSGSKM------------LKLVNVFIPEYRISKAKDMMEGKSAGFGLYPDSKIFYTPY 262 Query: 282 V-YVRQTIVADASNALSRAVCIATRYSAVR-RQFGAHNGGIETQVIDYKTQQNRLFPLLA 339 Y A + R + R R + N G+ T + R+ Sbjct: 263 RPYFASGFSAVSLGIAERMIEAFKEKQRNRVRAYTGANVGLATPAL------MRIAESTH 316 Query: 340 SAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLC 399 A R L+ + D + E A ++ + ++ Sbjct: 317 QVAAAR---ALLEKTWED-HRIHGLNHQYPNKETLAFWRTNQAYAVKMCIEAVDRLMAAA 372 Query: 400 GGHGYLWCSGLPELFAVYVPACTYEGD-NVVLQLQVARFLM 439 G ++ S L LF + V + R LM Sbjct: 373 GATSFMDNSELQRLFRDAHMTGAHAYTDYDVCAQILGRELM 413 >2RFQ-A nrPDB Length = 394 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 34/293 (11%), Positives = 76/293 (25%), Gaps = 43/293 (14%) Query: 141 GHGSNVQGLETTATFDPKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYG 200 G+ ++V ++++ P V+ W ++ AV+ +I +G+ Sbjct: 109 GNDTDV---RISSSYAPMGAGQVVDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVD 165 Query: 201 IHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSK 260 F++ I + ++ + V +P ++L + Sbjct: 166 FVSFLIPREDY------------RIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKAM 213 Query: 261 VTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRY--SAVRRQF----G 314 + + TI A A + VR F Sbjct: 214 SNLTAPGLERNTAPVYKMPWGTIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKA 273 Query: 315 AHNGGIETQVI----DYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATL 370 + + ++ D +L +A YA GE + + RL A Sbjct: 274 KDDPFAKVRIAEASSDIDAAWRQLSGNVADEYALLVAGEEVPF-----ELRLRARRDQVR 328 Query: 371 PEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTY 423 A ++ K ++ + L + + Sbjct: 329 ATGRAISSIDKLFESSGATALAN-------------GTPLQRFWRDAHAGRVH 368 >6FYV-A nrPDB Length = 337 Score = 32.9 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 16/43 (37%), Gaps = 2/43 (4%) Query: 554 NLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLYTQV 596 ++C ++ L L + DF+ N P Q + + Sbjct: 91 HVCIVFELLGLSTY--DFIKENSFLPFQIDHIRQMAYQICQSI 131 >1WU7-A nrPDB Length = 434 Score = 32.9 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 55/131 (41%), Gaps = 10/131 (7%) Query: 187 VVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLMFDH 246 +V+ +G+ I G + L ++ G+ +G G +++ + L ++ Sbjct: 273 IVFEAYDRSGQFRAILG-------GGRYDNLASLMSGESVPAVGFGMGDAVISLLLKREN 325 Query: 247 VRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIATRY 306 V+IPR++ + + +V + + ++ ++L M + + S L A I + Sbjct: 326 VQIPREKKSVYICRVGKINSSIMNEYSRKLRERGMNVTVEIMERGLSAQLKYASAIGADF 385 Query: 307 SAVRRQFGAHN 317 + + FG + Sbjct: 386 AVI---FGERD 393 >6A2F-A nrPDB Length = 358 Score = 32.5 bits (72), Expect = 0.59, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 52/147 (35%), Gaps = 14/147 (9%) Query: 268 VPSDVPKQLVYGTMVYVRQTIV--ADASNALSRAVCIATRYSAVRR-QFGAHNGGIETQV 324 +P+ L G M+Y + + A L A+ + + ++R G G T + Sbjct: 200 IPAAHMDWLRPGIMLYGSTPLADLSAAELGLKPAMSLGAQLISLREVAVGESVGYGATWI 259 Query: 325 IDYKTQQNRL-------FPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACT 377 + + + +P A A VG L V+ + A D + LPEA Sbjct: 260 AERPARIGTVSCGYADGYPRTAPAGTPVLVGGRRAILAGRVSMDMLAVDLSDLPEARVGD 319 Query: 378 AGLKSLTTTATADGIEECRKLCGGHGY 404 + ++E + CG GY Sbjct: 320 P----VELWGAGLSVDEVARACGTLGY 342 >4BQ4-A nrPDB Length = 750 Score = 32.5 bits (72), Expect = 0.63, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 6/71 (8%) Query: 111 KGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEF------VI 164 +G +Q+ +L+ +K IIG + + HGS GL A+ + + + VI Sbjct: 629 YKEGLPKQKWAFLAELDKPSIIGEFHIGAMDHGSYHPGLIHAASQADRGEMYKDYMQSVI 688 Query: 165 HTPTQTASKWW 175 P + W+ Sbjct: 689 DNPYFVGAHWF 699 >5Y0R-A nrPDB Length = 425 Score = 31.4 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 39/119 (32%), Gaps = 8/119 (6%) Query: 21 MKIVWAGSRHA-FEVSDRIARLVASDPVFEKSNRARLSRKELFKSTLRKCAHAFKRIIEL 79 + V GS E R+AR++ P + +K RK A + Sbjct: 96 VTDVVFGSESNDIEFLQRVARILYEQPDEYQKFLHEELKKGYSFPNARKYA-LMRYFSMK 154 Query: 80 RLNEEEAGRLRHFIDQPAYVDLHWGMFVP------AIKGQGTEEQQKKWLSLANKMQII 132 NEEE +L D +H + + IK G EE+ + + I Sbjct: 155 GWNEEEVLKLEKSNDILGVEYIHSALKIGSNIRFHTIKRVGAEEKDTSFRGRFSSATAI 213 >5E44-A nrPDB Length = 259 Score = 30.2 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 34/94 (36%), Gaps = 14/94 (14%) Query: 77 IELRLNEEEAGRLRHFIDQPAYVDLHWGMF-------------VPAIKGQGTEEQQKKWL 123 I LN+ E +L I++ + +F IK EQ + + Sbjct: 39 IPFTLNDSELDQLDEIIERKKPIQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDEQI 98 Query: 124 SLA-NKMQIIGCYAQTELGHGSNVQGLETTATFD 156 + ++G A TE H S Q LET+ + Sbjct: 99 TAFHLAGDLVGFDAITEAQHPSFAQALETSMVCE 132 >5LC2-A nrPDB Length = 205 Score = 29.4 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 31/99 (31%), Gaps = 9/99 (9%) Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIE 393 + P + A + L Y D +L + + + T+ T G Sbjct: 107 VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGS---------TSITNLGFR 157 Query: 394 ECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQL 432 + CGG G S + YEG V+++ Sbjct: 158 DNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEM 196 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.119 0.288 Lambda K H 0.267 0.0366 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,001,998 Number of Sequences: 36641 Number of extensions: 778150 Number of successful extensions: 2500 Number of sequences better than 10.0: 81 Number of HSP's better than 10.0 without gapping: 101 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 2030 Number of HSP's gapped (non-prelim): 143 length of query: 664 length of database: 10,336,785 effective HSP length: 103 effective length of query: 561 effective length of database: 6,562,762 effective search space: 3681709482 effective search space used: 3681709482 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.7 bits)