BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O64411 (500 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3L1R-A nrPDB 980 0.0 4FWE-A nrPDB 134 8e-32 3ABT-A nrPDB 116 3e-26 5L3D-A nrPDB 115 4e-26 2BXR-A nrPDB 82 6e-16 1O5W-A nrPDB 78 9e-15 3BI4-A nrPDB 75 5e-14 3KVE-A nrPDB 75 1e-13 1F8S-A nrPDB 73 3e-13 1REO-A nrPDB 73 4e-13 2BK5-A nrPDB 61 1e-09 3RHA-A nrPDB 51 1e-06 6CR0-A nrPDB 51 1e-06 4IV9-A nrPDB 50 3e-06 2VVL-G nrPDB 50 3e-06 3NK2-X nrPDB 43 3e-04 2IVE-A nrPDB 39 0.004 5NMX-A nrPDB 39 0.006 5MOG-A nrPDB 39 0.007 4MO2-B nrPDB 38 0.010 1SEZ-A nrPDB 37 0.023 1I8T-A nrPDB 35 0.051 3KYB-A nrPDB 35 0.056 4DGK-A nrPDB 34 0.12 6IK8-B nrPDB 34 0.14 3K30-A nrPDB 34 0.15 5BR7-A nrPDB 33 0.20 3X0V-A nrPDB 33 0.20 4YNU-A nrPDB 33 0.21 3WE0-A nrPDB 33 0.28 1NAA-A nrPDB 33 0.31 5L46-A nrPDB 32 0.43 4P9S-A nrPDB 32 0.49 3UKH-A nrPDB 32 0.49 2RGJ-A nrPDB 32 0.55 4RPJ-A nrPDB 32 0.70 3UP5-A nrPDB 32 0.89 3LOV-A nrPDB 32 0.89 4OVI-A nrPDB 32 0.91 3ORJ-A nrPDB 32 0.92 2JB2-A nrPDB 31 0.96 2TMD-A nrPDB 31 1.2 4ZCC-A nrPDB 31 1.5 2CVJ-A nrPDB 31 1.5 4AP1-A nrPDB 30 1.8 2P8E-A nrPDB 30 1.8 3BHF-A nrPDB 30 2.1 3RP7-A nrPDB 30 2.1 5ZBC-A nrPDB 30 2.3 1PJ5-A nrPDB 30 2.3 5J7X-A nrPDB 30 2.6 3GUV-A nrPDB 30 2.7 3KYD-B nrPDB 30 2.9 3KKJ-A nrPDB 30 3.6 5EQD-A nrPDB 29 3.7 4IVM-B nrPDB 29 3.7 2GMH-A nrPDB 29 3.7 3FXO-A nrPDB 29 3.8 2X86-A nrPDB 29 4.0 5ZYN-B nrPDB 29 4.8 4H7U-A nrPDB 29 4.8 3QJ4-A nrPDB 29 5.0 6FTI-5 nrPDB 29 5.2 6B67-A nrPDB 29 6.0 2LDB-A nrPDB 29 6.0 1ZOV-A nrPDB 28 6.5 1EQ2-A nrPDB 28 7.4 1JWB-B nrPDB 28 8.0 3ATQ-A nrPDB 28 8.6 1QEZ-A nrPDB 28 8.6 2WD5-A nrPDB 28 9.6 >3L1R-A nrPDB Length = 478 Score = 980 bits (2533), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/472 (99%), Positives = 471/472 (99%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW 88 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW Sbjct: 1 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW 60 Query: 89 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE 148 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE Sbjct: 61 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE 120 Query: 149 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 208 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL Sbjct: 121 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 180 Query: 209 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI 268 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI Sbjct: 181 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI 240 Query: 269 KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTK 328 KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYT Sbjct: 241 KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTM 300 Query: 329 IFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ 388 IFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ Sbjct: 301 IFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ 360 Query: 389 SDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA 448 SDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA Sbjct: 361 SDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA 420 Query: 449 PVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD 500 PVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD Sbjct: 421 PVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD 472 >4FWE-A nrPDB Length = 796 Score = 134 bits (337), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 136/472 (28%), Positives = 216/472 (45%), Gaps = 67/472 (14%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM-HKTNFAGINVELGANWVEGVN 93 VI++GAG +G++AA++L GI + +LEA D IGGR+ +F G+ V GA + VN Sbjct: 359 VIIIGAGPAGLAAARQLHNFGI-KVTVLEAKDRIGGRVWDDKSFKGVTVGRGA---QIVN 414 Query: 94 GGKMNPIWPIVNST-LKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIE-----LADSV 147 G NP+ + + + F D + ++GG + + KR++ L D V Sbjct: 415 GCINNPVALMCEQLGISMHKFGERCDLI------QEGGRITDPTIDKRMDFHFNALLDVV 468 Query: 148 EE------------MGEKLSATLHASGRDD---MSILAMQRLNEHQPNGPATPVDMVVDY 192 E +GEK+ A ++ S L Q L H N Sbjct: 469 SEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSN------------ 516 Query: 193 YKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSG 252 +Y S ++ F+ F D + GY ++ LA Sbjct: 517 --LEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTP--GYSVIIEKLA----------- 561 Query: 253 KIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPT 312 + +D +QL V+ I YS V V T D + YSA V+V+ L +LQ IQF P L Sbjct: 562 EGLD--IQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSE 619 Query: 313 WKVRAIYQFDMAVYTKIFLKFPRKFW-PEGKGREFFLY---ASSRRGYYGVWQEFEKQYP 368 K++AI + KI L+FP +FW + +G +FF + ++S+RG + V+ + + Q Sbjct: 620 KKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQ-K 678 Query: 369 DANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYK 428 +VL+ + E + D+Q + M LR++F ++VPD T V RW +D + + Sbjct: 679 KHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQ 738 Query: 429 GTFSNWPVGVNRYEYDQLRAPV-GRVYFTGEHTSEHYNGYVHGAYLSGIDSA 479 +S G + YD + + G V+F GE T+ H+ V GAYLSG+ A Sbjct: 739 MAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREA 790 >3ABT-A nrPDB Length = 662 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 94/337 (27%), Positives = 138/337 (40%), Gaps = 49/337 (14%) Query: 172 QRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFS----DFGDDVYFV 227 ++L E + N P+ D D+ FA N PL+T S D DD F Sbjct: 335 EKLQELEANPPSDVYLSSRDRQILDWHFAN----LEFANATPLSTLSLKHWDQDDDFEFT 390 Query: 228 AD----QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTV------ 277 + GY V LA ++LN VR+++Y+ G V Sbjct: 391 GSHLTVRNGYSCVPVALAEGL-------------DIKLNTAVRQVRYTASGCEVIAVNTR 437 Query: 278 KTEDNSVYSADYVMVSASLGVL--QSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPR 335 T +Y D V+ + LGVL Q +QF P LP WK A+ + K+ L F R Sbjct: 438 STSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDR 497 Query: 336 KFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKA 395 FW F + S G F Y A +LL V E + +E SD+ Sbjct: 498 VFW--DPSVNLFGHVGSTTASRGELFLFWNLY-KAPILLALVAGEAAGIMENISDDVIVG 554 Query: 396 EIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVG---- 451 + +L+ +F VP + +V RW +D + +G++S G + +YD + P+ Sbjct: 555 RCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPS 614 Query: 452 ---------RVYFTGEHTSEHYNGYVHGAYLSGIDSA 479 R++F GEHT +Y VHGA LSG+ A Sbjct: 615 IPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 651 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 59/104 (56%), Gaps = 2/104 (1%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 +VI++G+G+SG++AA++L G+ D+ +LEA D +GGR+ +LGA V G+ Sbjct: 109 KVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 167 Query: 94 GGKMNPIWPIVNSTL-KLRNFRSDFDYLAQNVYKEDGGVYDEDY 136 G M + VN L K++ ++ Q V KE + ++++ Sbjct: 168 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEF 211 >5L3D-A nrPDB Length = 852 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 95/337 (28%), Positives = 140/337 (41%), Gaps = 49/337 (14%) Query: 172 QRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFS----DFGDDVYFV 227 ++L E + N P+ D D+ FA N PL+T S D DD F Sbjct: 506 EKLQELEANPPSDVYLSSRDRQILDWHFAN----LEFANATPLSTLSLKHWDQDDDFEFT 561 Query: 228 AD----QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTV------ 277 + GY V LA + +D ++LN VR+++Y+ G V Sbjct: 562 GSHLTVRNGYSCVPVALA-----------EGLD--IKLNTAVRQVRYTASGCEVIAVNTR 608 Query: 278 KTEDNSVYSADYVMVSASLGVL--QSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPR 335 T +Y D V+ + LGVL Q +QF P LP WK A+ + K+ L F R Sbjct: 609 STSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDR 668 Query: 336 KFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKA 395 FW F + S G F Y A +LL V E + +E SD+ Sbjct: 669 VFW--DPSVNLFGHVGSTTASRGELFLFWNLY-KAPILLALVAGEAAGIMENISDDVIVG 725 Query: 396 EIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVG---- 451 + +L+ +F VP + +V RW +D + +G+ S G + +YD + P+ Sbjct: 726 RCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSHSYVAAGSSGNDYDLMAQPITPGPS 785 Query: 452 ---------RVYFTGEHTSEHYNGYVHGAYLSGIDSA 479 R++F GEHT +Y VHGA LSG+ A Sbjct: 786 IPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 59/104 (56%), Gaps = 2/104 (1%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 +VI++G+G+SG++AA++L G+ D+ +LEA D +GGR+ +LGA V G+ Sbjct: 280 KVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 338 Query: 94 GGKMNPIWPIVNSTL-KLRNFRSDFDYLAQNVYKEDGGVYDEDY 136 G M + VN L K++ ++ Q V KE + ++++ Sbjct: 339 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEF 382 >2BXR-A nrPDB Length = 527 Score = 82.0 bits (201), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 98/474 (20%), Positives = 201/474 (42%), Gaps = 52/474 (10%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWVEGVN 93 V+V+G G+SG+SAAK L+E G++ +L+LEA D +GGR + ++ V++G +V Sbjct: 16 VVVIGGGISGLSAAKLLTEYGVS-VLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQ 74 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGG---VYDEDYVQKRIELADSVEEM 150 + + T K+ Y+ Y G V++ L +++ M Sbjct: 75 NRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNM 134 Query: 151 GEKL--SATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEF------AEP 202 G+++ A A D + M+ L + + +F Y F +EP Sbjct: 135 GKEIPTDAPWEAQHADKWDKMTMKELIDK--------ICWTKTARRFAYLFVNINVTSEP 186 Query: 203 PRVTSLQ---------NTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGK 253 V++L T + + ++ G + FV +GQ ++ Sbjct: 187 HEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGG-----------SGQ---VSERIMD 232 Query: 254 IVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTW 313 ++ +++LN V + S + ++T ++ Y YV ++A L + I F+P+LP Sbjct: 233 LLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYV-INAIPPTLTAK-IHFRPELPAE 290 Query: 314 KVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANV- 372 + + I + M K + + FW K +++ + + PD ++ Sbjct: 291 RNQLIQRLPMGAVIKCMMYYKEAFW---KKKDYCGCMIIEDEDAPISITLDDTKPDGSLP 347 Query: 373 -LLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTF 431 ++ + ++ R+ + E K +I ++ K+ ++ W +++ G + Sbjct: 348 AIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCY 407 Query: 432 SNW-PVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILIN 484 + + P G+ +R PVGR++F G T+ ++GY+ GA +G +A ++N Sbjct: 408 TAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLN 461 >1O5W-A nrPDB Length = 534 Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 107/477 (22%), Positives = 209/477 (43%), Gaps = 50/477 (10%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWVEGVN 93 V+V+G G+SG++AAK LSE I ++L+LEA D +GGR + + V++G +V Sbjct: 24 VVVIGGGISGLAAAKLLSEYKI-NVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYV---- 78 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFD-----YLAQNVYKEDGG---VYDEDYVQKRIELAD 145 G N I + + L + ++ + + Y+ Y G V++ L Sbjct: 79 GPTQNRILRL-SKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWR 137 Query: 146 SVEEMGEKL--SATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPP 203 +++EMG+++ A A + + M+ L + + +F Y F Sbjct: 138 TMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDK--------ICWTKTAREFAYLFVNI- 188 Query: 204 RVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYL--AGQYLKTDDKSGKIVDP---- 257 VTS + V F +++V Q G A ++ + GQ K SG++ + Sbjct: 189 NVTSEPHEVSALWF------LWYV-RQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGL 241 Query: 258 ---RLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWK 314 +++L+ V I + + V+T ++ Y YV +SA +L + I FKP+LP + Sbjct: 242 LGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYV-ISAIPPILTAK-IHFKPELPPER 299 Query: 315 VRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANV-- 372 + I + M K + + FW K +++ + + PD ++ Sbjct: 300 NQLIQRLPMGAVIKCMVYYKEAFW---KKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPA 356 Query: 373 LLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFS 432 ++ + ++ R+ + + K +I ++ K+ ++ W +++ G ++ Sbjct: 357 IMGFILARKADRLAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYT 416 Query: 433 NW-PVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQK 488 + P G+ +R PVGR+YF G T+ ++GY+ GA +G +A ++N K Sbjct: 417 AYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGK 473 >3BI4-A nrPDB Length = 516 Score = 75.5 bits (184), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 85/340 (25%), Positives = 142/340 (41%), Gaps = 67/340 (19%) Query: 30 TVGP---RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK-TNFAGINVELG 85 TV P +VI++GAG++G+ AA L + GI D L+LEA D +GGR+ T + G ++G Sbjct: 3 TVSPAKKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIG 62 Query: 86 ANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQN-VY-KEDGGVYDEDYVQKRIEL 143 A+W NP++ + + L L + R+ F + N +Y E+ G D D + +E+ Sbjct: 63 ASWHHDT---LTNPLF-LEEAQLSLNDGRTRFVFDDDNFIYIDEERGRVDHDK-ELLLEI 117 Query: 144 ADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPP 203 D ++MS A ++H + +V+ Y +F Sbjct: 118 VD------------------NEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLTND 159 Query: 204 RVTSLQNTVPLATFSDF----------GDDVYFVADQR-----GYEAVVYYLAGQYLKTD 248 ++ L L + + D YF R Y++VV +A + + Sbjct: 160 QIRYLPQ---LCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQN- 215 Query: 249 DKSGKIVDPRLQLNKVVREIKYSPG-GVTVKTEDNSVYSADYVMVSASLGVLQSDL---- 303 L+L+ V+ I P VTV ED +VY+ADYV+++ VL + Sbjct: 216 ---------WLKLSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEK 266 Query: 304 -----IQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFW 338 I+F+P L A + K+ +F W Sbjct: 267 NLRGRIEFQPPLKPVIQDAFDKIHFGALGKVIFEFEECCW 306 Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 7/83 (8%) Query: 400 VLRKMFPGKDVPDAT-----DILVPRWWSDRFYKGTFSNWPVGVNRYEY--DQLRAPVGR 452 V+ M P +++ +A +I+V W D + +G +S G + + R Sbjct: 414 VIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPGDDPVDMVVAMSNGQDSR 473 Query: 453 VYFTGEHTSEHYNGYVHGAYLSG 475 + F GEHT G +GA+ SG Sbjct: 474 IRFAGEHTIMDGAGCAYGAWESG 496 >3KVE-A nrPDB Length = 486 Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 121/496 (24%), Positives = 212/496 (42%), Gaps = 73/496 (14%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM--HKT 75 L +A++G L T P+ V+VVGAGMSG+SAA L+ AG + +LEA++ GGR+ H+ Sbjct: 20 LEIARNG-LKKTSNPKHVVVVGAGMSGLSAAYVLAGAG-HKVTVLEASERAGGRVRTHRN 77 Query: 76 NFAGINVELGANWVEGVNGGKMNPIWPIVNS-TLKLRNFRSDFD---YLAQNVYKEDGGV 131 + G LG + K + + L L F + D Y +N+ K G V Sbjct: 78 SKEGWYANLGPMRIPE----KHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEV 133 Query: 132 -YDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQ---------PNG 181 D ++ ++ ++ + G+ +L ++ +D LN++ G Sbjct: 134 NKDPGLLKYPVKPSEEGKSAGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEG 193 Query: 182 PATP--VDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYY 239 +P VDM+ D D + + SL++ DD++ YE Sbjct: 194 NLSPGAVDMIGDLLNEDSGYY-VSFIESLKH-----------DDIF------AYEKRFDE 235 Query: 240 LAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVK----TEDNSVYSADYVMVSAS 295 + G + + ++ +++ N V +I+ + VTV +D S +ADYV+V + Sbjct: 236 IVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVCTT 295 Query: 296 LGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEG--KGREFFLYASSR 353 + IQF+P LP K A+ TKIFL KFW + G + SR Sbjct: 296 SRAARR--IQFEPPLPPKKQHALRSVHYRSGTKIFLTCSSKFWEDDGIHGGKSTTDLPSR 353 Query: 354 RGYYGVWQEFEKQYPDANV-----LLVTVTDEESRRIEQQSDEQTKAEIM---QVLRKMF 405 Y YP+ N +++ + Q + A+I+ L Sbjct: 354 FIY----------YPNHNFSTGVGVIIAYGIGDDANFFQALKFKDCADIVFNDLSLIHQL 403 Query: 406 PGKDVPD-ATDILVPRWWSDRFYKGTFSNW-PVGVNRYEYDQLRAPVGRVYFTGEHTSEH 463 P +++ ++ +W D++ G + + P R+ + L AP GR++F GE+T+E Sbjct: 404 PKEEIQSFCYPSMIQKWSLDKYAMGAITTFTPYQFQRFS-EALTAPQGRIFFAGEYTAEA 462 Query: 464 YNGYVHGAYLSGIDSA 479 + G++ SG+ +A Sbjct: 463 H-GWIDSTIKSGLTAA 477 >1F8S-A nrPDB Length = 498 Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 134/525 (25%), Positives = 214/525 (40%), Gaps = 100/525 (19%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 L +A++G L AT P+ V++VGAGM+G+SAA L+ AG + +LEA++ GGR+ Sbjct: 20 LEIARNG-LKATSNPKHVVIVGAGMAGLSAAYVLAGAG-HQVTVLEASERPGGRVRTYR- 76 Query: 78 AGINVELGANWVEGVNGGKMNPIWPIVNS-----TLKLRNFRSDFD---YLAQNVYKEDG 129 N E G W + ++ IV L+L F + D Y +N+ K+ G Sbjct: 77 ---NEEAG--WYANLGPMRLPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVG 131 Query: 130 GVYDE----DYVQKRIELADSVEEM-GEKLSATLHASGRDDMSILAMQRLNEHQ------ 178 V + Y K E S ++ E L + R + S + LN++ Sbjct: 132 EVKKDPGLLKYPVKPSEAGKSAGQLYEESLGKVVEELKRTNCSYI----LNKYDTYSTKE 187 Query: 179 ---PNGPATP--VDMVVD-------YY-------KFDYEFAEPPRVTSL---QNTVPLAT 216 G +P VDM+ D YY K D FA R + + +P A Sbjct: 188 YLIKEGDLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVDGMDKLPTAM 247 Query: 217 FSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVT 276 + D D V+F A Q +K K+ VV E T Sbjct: 248 YRDIQDKVHFNA--------------QVIKIQQNDQKVT--------VVYE--------T 277 Query: 277 VKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRK 336 + E SV +ADYV+V + ++ LI+F P L K A+ TKIFL K Sbjct: 278 LSKETPSV-TADYVIVCTTSRAVR--LIKFNPPLLPKKAHALRSVHYRSGTKIFLTCTTK 334 Query: 337 FWPEG--KGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTK 394 FW + G + SR YY + + +++ + Q D + Sbjct: 335 FWEDDGIHGGKSTTDLPSRFIYYP-----NHNFTNGVGVIIAYGIGDDANFFQALDFKDC 389 Query: 395 AEIM---QVLRKMFPGKDVPD-ATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPV 450 A+I+ L P KD+ ++ +W D++ G + + ++ D L A Sbjct: 390 ADIVFNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYAMGGITTFTPYQFQHFSDPLTASQ 449 Query: 451 GRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHV 495 GR+YF GE+T++ + G++ SG+ +A +N A + H+ Sbjct: 450 GRIYFAGEYTAQAH-GWIDSTIKSGLRAARD-VNLASENPSGIHL 492 >1REO-A nrPDB Length = 486 Score = 72.8 bits (177), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 128/503 (25%), Positives = 211/503 (41%), Gaps = 87/503 (17%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 L +A++G L AT P+ V+VVGAGMSG+SAA LS AG + +LEA++ GGR+ Sbjct: 20 LEIARNG-LKATSNPKHVVVVGAGMSGLSAAYVLSGAG-HQVTVLEASERAGGRVRTYR- 76 Query: 78 AGINVELGANWVEGVNGGKMNPIWPIVNS-----TLKLRNFRSDFD---YLAQNVYKEDG 129 +W + ++ IV L+L F + D Y +N+ K G Sbjct: 77 -----NDKEDWYANLGPMRLPEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVG 131 Query: 130 GVYDE----DYVQKRIELADSVEEM-GEKLSATLHASGRDDMSILAMQRLNEHQ------ 178 V + Y K E S ++ E L + R + S + LN++ Sbjct: 132 EVKKDPGVLKYPVKPSEEGKSAGQLYEESLGKVVEELKRTNCSYI----LNKYDTYSTKE 187 Query: 179 ---PNGPATP--VDMVVDYYKFD--YEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQR 231 G +P VDM+ D D Y + P SL++ DD++ Sbjct: 188 YLLKEGNLSPGAVDMIGDLMNEDSGYYVSFP---ESLRH-----------DDIF------ 227 Query: 232 GYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTV----KTEDNSVYSA 287 YE + G K + ++ ++ LN V +I+ + VTV ++ + +A Sbjct: 228 AYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTA 287 Query: 288 DYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWP-EG-KGRE 345 DYV+V + + I+F+P LP K A+ TKIFL +KFW EG G + Sbjct: 288 DYVIVCTTSRATRR--IKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGK 345 Query: 346 FFLYASSRRGYYGVWQEFEKQYPDANV-----LLVTVTDEESRRIEQQSDEQTKAEIM-- 398 SR Y YP+ N +++ + Q D + A+I+ Sbjct: 346 STTDLPSRFIY----------YPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVIN 395 Query: 399 -QVLRKMFPGKDVPD-ATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFT 456 L P +++ ++ +W D++ G + + ++ + L A V R+YF Sbjct: 396 DLSLIHQLPREEIQTFCYPSMIQKWSLDKYAMGGITTFTPYQFQHFSESLTASVDRIYFA 455 Query: 457 GEHTSEHYNGYVHGAYLSGIDSA 479 GEHT+E + G++ SG+ +A Sbjct: 456 GEHTAEAH-GWIDSTIKSGLRAA 477 >2BK5-A nrPDB Length = 520 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 49/236 (20%), Positives = 107/236 (45%), Gaps = 12/236 (5%) Query: 258 RLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVM--VSASLGVLQSDLIQFKPKLPTWKV 315 R++L + V I + V V+T ++ +Y A YV+ + +LG+ I F P LP + Sbjct: 228 RVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMK----IHFNPPLPMMRN 283 Query: 316 RAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDAN--VL 373 + I + + K + + FW + +++ V + P+ N + Sbjct: 284 QMITRVPLGSVIKCIVYYKEPFW---RKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAI 340 Query: 374 LVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSN 433 + + ++R++ + + E+ ++ ++ K+ + + W +++ G ++ Sbjct: 341 MGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTT 400 Query: 434 W-PVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQK 488 + P G+ LR PV R+YF G T+ H++GY+ GA +G +A +++ K Sbjct: 401 YFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGK 456 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 35/50 (70%), Gaps = 2/50 (4%) Query: 41 GMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWV 89 G+SG++AAK L ++G+ ++++LEA D +GGR + + V+LG ++V Sbjct: 13 GISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 >3RHA-A nrPDB Length = 482 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 37/55 (67%), Gaps = 1/55 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWV 89 V++VGAG SG++AA+ L +AG++ + +LEA D +GGR G +E+G WV Sbjct: 10 VVIVGAGPSGLTAARELKKAGLS-VAVLEARDRVGGRTWTDTIDGAMLEIGGQWV 63 >6CR0-A nrPDB Length = 440 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 28/55 (50%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWV 89 IVVGAG SG+ AA+ LS G + +LI+EA +GGR H NF G VE+G V Sbjct: 11 AIVVGAGFSGLVAARELSAQGRS-VLIIEARHRLGGRTHVVNFLGRPVEIGGAGV 64 Score = 34.7 bits (78), Expect = 0.092, Method: Compositional matrix adjust. Identities = 48/213 (22%), Positives = 89/213 (41%), Gaps = 21/213 (9%) Query: 265 VREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMA 324 V + + GVTV D V+ A +++ V ++F+P LP K I +MA Sbjct: 234 VEAVAQTDNGVTVTLADKRVFRALTCVLTLPTKVYAD--VRFEPPLPPEKRAFIEHAEMA 291 Query: 325 VYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRR 384 ++++ + F + + V Q + Y D ++ +T Sbjct: 292 DGAELYVHVRQNLG------NTFTFCDDPNPFNAV-QTY--AYDDELGTILKITIGRQSL 342 Query: 385 IEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVG-VNRYEY 443 I ++ + AEI RK+ +V +A L W D + + ++ G +RY+ Sbjct: 343 INLENFDAIAAEI----RKIHGDVEVLEA---LPYNWAMDEYARTSYPAMRKGWFSRYK- 394 Query: 444 DQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGI 476 + P R++F G T++ ++ Y+ GA SGI Sbjct: 395 -DMAKPENRLFFAGSATADGWHEYIDGAIESGI 426 >4IV9-A nrPDB Length = 557 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 24/50 (48%), Positives = 33/50 (66%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 A T PRV +VGAG+SG+ AA L AG+ D+++ E+ D IGGR+ F Sbjct: 34 AGTPTPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVF 83 >2VVL-G nrPDB Length = 495 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 26/56 (46%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVE 90 VIV+G G G++A + L+ AG LL LEA D IGGR +N G E+G WV Sbjct: 42 VIVIGGGYCGLTATRDLTVAGFKTLL-LEARDRIGGRSWSSNIDGYPYEMGGTWVH 96 Score = 36.2 bits (82), Expect = 0.036, Method: Compositional matrix adjust. Identities = 48/227 (21%), Positives = 83/227 (36%), Gaps = 31/227 (13%) Query: 265 VREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMA 324 VR + V D + A V+ + L VL + IQF P L T ++ A+ ++ Sbjct: 279 VRSVVNERDAARVTARDGREFVAKRVVCTIPLNVLST--IQFSPALSTERISAMQAGHVS 336 Query: 325 VYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEK--------QYPDANVLLVT 376 + TK+ + K R + G+ F K P N LV Sbjct: 337 MCTKVHAEVDNK---------------DMRSWTGIAYPFNKLCYAIGDGTTPAGNTHLVC 381 Query: 377 VTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPV 436 + + Q DE + E ++ + ++ PG ++ W D F KG + Sbjct: 382 FGTDAN---HIQPDEDVR-ETLKAVGQLAPG--TFGVKRLVFHNWVKDEFAKGAWFFSRP 435 Query: 437 GVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILI 483 G+ LR G V F + + ++ GA G +A +++ Sbjct: 436 GMVSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVL 482 >3NK2-X nrPDB Length = 431 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 60/259 (23%), Positives = 100/259 (38%), Gaps = 37/259 (14%) Query: 238 YYLAGQYLKTDD----KSGKIVD------PRLQLNKVVREIKYSPGGVTVKTEDNSVYSA 287 Y + G L D+ S +VD P ++L VV I S V V +D + A Sbjct: 189 YSILGVVLSLDEVFSNGSADLVDAMSQEIPEIRLQTVVTGIDQSGDVVNVTVKDGHAFQA 248 Query: 288 DYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFF 347 V+V+ + + I F P LP + I + KI + +G E Sbjct: 249 HSVIVATPMNTWRR--IVFTPALPERRRSVIEEGHGGQGLKILIHV--------RGAEAG 298 Query: 348 LYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKM-FP 406 + + ++ E ++ LLV TD S + K ++ L ++ Sbjct: 299 IECVGDGIFPTLYDYCEVS--ESERLLVAFTDSGS--FDPTDIGAVKDAVLYYLPEVEVL 354 Query: 407 GKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNG 466 G D D W +D ++G + VG + +L P GR++F G S + G Sbjct: 355 GIDYHD--------WIADPLFEGPWVAPRVGQFSRVHKELGEPAGRIHFVGSDVSLEFPG 406 Query: 467 YVHGAYLSGIDSAEILINC 485 Y+ GA +++AE +N Sbjct: 407 YIEGA----LETAECAVNA 421 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 4/57 (7%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMH---KTNFAGINVELGANWV 89 IVVG G SG+ AA+ L+ AG +L+LE + +GGR + N G+ VE+G ++ Sbjct: 5 IVVGGGFSGLKAARDLTNAG-KKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYL 60 >2IVE-A nrPDB Length = 478 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 30 TVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGAN 87 T G V VVG G+SG++ A L G TD ++LE++ +GG + AG VE G N Sbjct: 14 TTGMNVAVVGGGISGLAVAHHLRSRG-TDAVLLESSARLGGAVGTHALAGYLVEQGPN 70 >5NMX-A nrPDB Length = 425 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 30/43 (69%), Gaps = 1/43 (2%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTN 76 RV V+GAG SG++AA+ L +AG ++++ E H+GG + T+ Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGF-EVMVFERYHHVGGTWNYTD 44 >5MOG-A nrPDB Length = 497 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 18/39 (46%), Positives = 30/39 (76%), Gaps = 1/39 (2%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM 72 +V++ GAG++G+S AK L++AG +L LEA D +GG++ Sbjct: 19 QVVIAGAGLAGLSTAKYLADAGHKPIL-LEARDVLGGKI 56 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Query: 365 KQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSD 424 K+Y D N ++ + + +SD + MQ L K+FP + D + + ++ Sbjct: 353 KEYYDPNRSMLELVFAPAEEWVGRSDTEIIEATMQELAKLFPDEIAADQSKAKILKYHVV 412 Query: 425 RFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILI 483 + + + P R+P+ Y G++T + Y + GA LSG A+ ++ Sbjct: 413 KTPRSVYKTIPDCEPCRPLQ--RSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQSVV 469 >4MO2-B nrPDB Length = 368 Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINV-ELGANWVEGVNG 94 ++VG+G+ G A +E G T L++E +HIGG + N INV + GA+ + Sbjct: 5 LIVGSGLFGSIFAYEATEKGYT-CLVVEQREHIGGNCYTENIKNINVHKYGAHIFRTSDQ 63 Query: 95 GKMNPIWPIVNSTLKLRNF 113 IW +N + +F Sbjct: 64 N----IWDYMNQFCEFNHF 78 >1SEZ-A nrPDB Length = 504 Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust. Identities = 20/54 (37%), Positives = 34/54 (62%), Gaps = 1/54 (1%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGAN 87 RV V+GAG+SG++AA +L G+ ++ + EA GG++ + G+ + GAN Sbjct: 15 RVAVIGAGVSGLAAAYKLKIHGL-NVTVFEAEGKAGGKLRSVSQDGLIWDEGAN 67 >1I8T-A nrPDB Length = 367 Score = 35.4 bits (80), Expect = 0.051, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGG 95 I+VG+G+ G A L + +L++E +HIGG + + GI + + N Sbjct: 5 IIVGSGLFGAVCANELKKLN-KKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTND- 62 Query: 96 KMNPIWPIVNSTLKLRNF 113 IW VN ++ F Sbjct: 63 --KYIWDYVNDLVEFNRF 78 >3KYB-A nrPDB Length = 390 Score = 35.4 bits (80), Expect = 0.056, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINV 82 ++++VGAG SG ++L+E G + I++ DHIGG + + NV Sbjct: 5 KILIVGAGFSGAVIGRQLAEKG-HQVHIIDQRDHIGGNSYDARDSETNV 52 >4DGK-A nrPDB Length = 501 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 37 VVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELG 85 V+GAG G++ A RL AGI +L+LE D GGR + G + G Sbjct: 6 VIGAGFGGLALAIRLQAAGIP-VLLLEQRDKPGGRAYVYEDQGFTFDAG 53 >6IK8-B nrPDB Length = 718 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 7/76 (9%) Query: 426 FYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYV------HGAYLSGIDSA 479 +YK TF N P G + D G+++ GE H+ GY+ +Y + Sbjct: 601 WYKATF-NAPGGNDPLALDMASMGKGQIWINGEGVGRHWPGYIAQGDCSKCSYAGTFNEK 659 Query: 480 EILINCAQKKMCKYHV 495 + NC Q YHV Sbjct: 660 KCQTNCGQPSQRWYHV 675 >3K30-A nrPDB Length = 690 Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust. Identities = 19/39 (48%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM 72 RV+VVGAG SG+ AA+ L G D+++ EA +GGR+ Sbjct: 393 RVLVVGAGPSGLEAARALGVRGY-DVVLAEAGRDLGGRV 430 >5BR7-A nrPDB Length = 393 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 7/74 (9%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL---GANWVEG 91 +IVVG+G+ G++ A+R + +LI+E H+GG + +E+ GA+ Sbjct: 6 LIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHT 65 Query: 92 VNGGKMNPIWPIVN 105 N +W VN Sbjct: 66 SN----KRVWDYVN 75 >3X0V-A nrPDB Length = 541 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 2/47 (4%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLL--ILEATDHIGGRMHKTNFA 78 +V +VGAG+SG+ A L + I +L I E++ GGR++ +F Sbjct: 9 KVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFT 55 >4YNU-A nrPDB Length = 571 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 26/51 (50%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA 86 IVVG G SG+ A RLSE +L+LEA + TN G + G+ Sbjct: 9 IVVGGGTSGLVVANRLSENPDVSVLLLEAGASVFNNPDVTNANGYGLAFGS 59 >3WE0-A nrPDB Length = 580 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 5/62 (8%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFA---GINVEL 84 AA G V +VGAG++G+ AA L + G+ ++ EA+ +GGR+ F GI EL Sbjct: 61 AARHGEEVAIVGAGIAGLVAAYELMKLGLKP-VVYEAS-KMGGRLRSQAFNGTDGIIAEL 118 Query: 85 GA 86 G Sbjct: 119 GG 120 >1NAA-A nrPDB Length = 541 Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust. Identities = 21/39 (53%), Positives = 25/39 (64%), Gaps = 5/39 (12%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILE----ATDHIGG 70 I+VGAG GI AA RLSEAG +L+LE +T GG Sbjct: 6 IIVGAGPGGIIAADRLSEAG-KKVLLLERGGPSTKQTGG 43 >5L46-A nrPDB Length = 841 Score = 32.3 bits (72), Expect = 0.43, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 24/36 (66%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 +++G G G+S A L++AG+ D+++LE ++ G Sbjct: 25 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 60 >4P9S-A nrPDB Length = 848 Score = 32.3 bits (72), Expect = 0.49, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 24/36 (66%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 +++G G G+S A L++AG+ D+++LE ++ G Sbjct: 26 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 61 >3UKH-A nrPDB Length = 519 Score = 32.3 bits (72), Expect = 0.49, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 25/36 (69%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 V+V+GAG +G+ AAKRL++ +I+++ + GG Sbjct: 9 VLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGG 44 >2RGJ-A nrPDB Length = 402 Score = 32.3 bits (72), Expect = 0.55, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA 86 +++ GAG+ G+S A L +AGI + +LE++ I + GIN++ A Sbjct: 7 ILIAGAGIGGLSCALALHQAGIGKVTLLESSSEI-----RPLGVGINIQPAA 53 >4RPJ-A nrPDB Length = 399 Score = 32.0 bits (71), Expect = 0.70, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 7/83 (8%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL---GANWVEG 91 + VVG+G G++ A+R++ +L+LE HIGG + +E+ GA+ Sbjct: 10 LFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHT 69 Query: 92 VNGGKMNPIWPIVNSTLKLRNFR 114 N +W V ++R Sbjct: 70 SN----KRVWDYVRQFTDFTDYR 88 >3UP5-A nrPDB Length = 545 Score = 31.6 bits (70), Expect = 0.89, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVE 83 +V+GAG++GI A +++AG+ +L +EA + +GG + + G ++ Sbjct: 12 AVVIGAGVTGIYQAFLINQAGM-KVLGIEAGEDVGGTWYWNRYPGCRLD 59 >3LOV-A nrPDB Length = 475 Score = 31.6 bits (70), Expect = 0.89, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLI--LEATDHIGGRMHKTNFAGINVELGAN 87 R+++VG G++G++AA +E DL I LEA + +GG++ G +E G + Sbjct: 6 RLVIVGGGITGLAAAY-YAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPD 60 >4OVI-A nrPDB Length = 542 Score = 31.6 bits (70), Expect = 0.91, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 V+VVGAG SG+ A RL E G + ++E +GG + + G ++ Sbjct: 19 VLVVGAGFSGLYALYRLRELG-RSVHVIETAGDVGGVWYWNRYPGARCDI 67 >3ORJ-A nrPDB Length = 439 Score = 31.6 bits (70), Expect = 0.92, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Query: 18 ALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 A S+ + + VG +IV G+G++ I+ +T+ +I +D G Sbjct: 113 APSITKISNCMPNVGEPIIVYGSGLTEIAKVVFPGNVVVTEGII---SDLDGEYFMVDMP 169 Query: 78 AGINVELGANWVEGVNGGKMNP 99 AG++ E G+ +VEG NGG +P Sbjct: 170 AGVSEEGGSIFVEGSNGGAYSP 191 >2JB2-A nrPDB Length = 489 Score = 31.2 bits (69), Expect = 0.96, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 7/72 (9%) Query: 412 DATDILVPRWWSDRFYKGTFSNWPVGVNRY------EYDQLRAPVGRVYFTGEHTSEHYN 465 D + W ++ + ++NW + EY++L PV ++YF G+H S Sbjct: 406 DISSSFSGSWRRTKYSESAWANWAGSGGSHGGAATPEYEKLLEPVDKIYFAGDHLSNAI- 464 Query: 466 GYVHGAYLSGID 477 + HGA S D Sbjct: 465 AWQHGALTSARD 476 Score = 28.1 bits (61), Expect = 9.4, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 1/38 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM 72 V+V+G G +G+ +A L +AG + +LEA GGR+ Sbjct: 14 VVVLGGGPAGLCSAFELQKAGYK-VTVLEARTRPGGRV 50 >2TMD-A nrPDB Length = 729 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK 74 V++VGAG SG AA+ L E+G T + + + + IGG +++ Sbjct: 392 VLIVGAGPSGSEAARVLMESGYT-VHLTDTAEKIGGHLNQ 430 >4ZCC-A nrPDB Length = 336 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGAN 87 + ++G G++G+SAA+ L+ AG + + + + GGRM ++++GA Sbjct: 5 IAIIGTGIAGLSAAQALTSAG-HQVHLFDKSRGSGGRMSSKRSDAGSLDMGAQ 56 >2CVJ-A nrPDB Length = 180 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 26/46 (56%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGI 80 VIVVG G SG+SAA L+ AG+ L++ + G N+ G+ Sbjct: 4 VIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGL 49 >4AP1-A nrPDB Length = 549 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 V+VVGAG++G+ A R G+T + EA +GG + + G ++ Sbjct: 24 VVVVGAGIAGLYAIHRFRSQGLT-VRAFEAASGVGGVWYWNRYPGARCDV 72 >2P8E-A nrPDB Length = 307 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Query: 135 DYVQKRIELADSVEEMGE-KLSATLHASGRDDMSILAMQRLNE 176 +YV+ R+E++D +E + + LH RD+MSI+ + NE Sbjct: 258 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNE 300 >3BHF-A nrPDB Length = 390 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 3/41 (7%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATD--HIGGRMH 73 VIVVGAG G++A +L++ G+ LL+ +A D H G H Sbjct: 7 VIVVGAGSMGMAAGYQLAKQGVKTLLV-DAFDPPHTNGSHH 46 >3RP7-A nrPDB Length = 407 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 23/35 (65%), Gaps = 1/35 (2%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHI 68 + IV+GAG+ G+SAA L ++GI D + EA I Sbjct: 25 KAIVIGAGIGGLSAAVALKQSGI-DCDVYEAVKEI 58 >5ZBC-A nrPDB Length = 451 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 31/129 (24%), Positives = 60/129 (46%), Gaps = 26/129 (20%) Query: 35 VIVVGAGMSGISAAKRLSEAGIT---DLLILEATDHIGGRMHKTNFAG-INVELGANWVE 90 + +VGAG+SG++ A L ++ L I + GGR+ G ++ELGA Sbjct: 27 ICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKMLDGKASIELGA---- 82 Query: 91 GVNGGKMNP-IWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRI-----ELA 144 G+ +P + P S ++ + +S+ Q +K +VQ+++ EL+ Sbjct: 83 ----GRYSPQLHPHFQSAMQHYSQKSEVYPFTQLKFKS--------HVQQKLKRAMNELS 130 Query: 145 DSVEEMGEK 153 ++E G++ Sbjct: 131 PRLKEHGKE 139 >1PJ5-A nrPDB Length = 830 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 9/53 (16%) Query: 33 PRVIVVGAGMSGISAAKRLSEAGITDLLILE---------ATDHIGGRMHKTN 76 PR++++GAG+ G + A L G ++ +L+ +T H G + +TN Sbjct: 5 PRIVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTN 57 >5J7X-A nrPDB Length = 549 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 24/50 (48%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 +++G+G SGI +L + + I EA IGG + + G V+ Sbjct: 15 ALIIGSGFSGIYLLHKLRDELKLKVKIFEAESDIGGTWNNNRYPGARVDC 64 >3GUV-A nrPDB Length = 167 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 25/39 (64%), Gaps = 1/39 (2%) Query: 238 YYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVT 276 Y + G+Y + KSGK ++ R+Q N+++ +IK GV+ Sbjct: 40 YEIVGEY-EDAGKSGKSIEGRIQFNRMMEDIKSGKDGVS 77 >3KYD-B nrPDB Length = 551 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 3/54 (5%) Query: 16 LLALSLAQHGSLA-ATVGPRVIVVGAGMSGISAAKRLSEAGIT--DLLILEATD 66 L+ALS LA A G RV+VVGAG G K L G + DL+ L+ D Sbjct: 2 LMALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTID 55 >3KKJ-A nrPDB Length = 336 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGAN 87 + ++G G++G+SAA+ L+ AG + + + + GGRM +++GA Sbjct: 5 IAIIGTGIAGLSAAQALTAAG-HQVHLFDKSRGSGGRMSSKRSDAGALDMGAQ 56 >5EQD-A nrPDB Length = 400 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 22/36 (61%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 + VVG+G G++ A+R + +L++E HIGG Sbjct: 7 LFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGG 42 >4IVM-B nrPDB Length = 483 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 28/41 (68%), Gaps = 1/41 (2%) Query: 31 VGPRVIVVGAGMSGISAAKRLSEAGITDLLIL-EATDHIGG 70 +G V+V+G G+SG++A+ LS A ++L E+++ +GG Sbjct: 7 MGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47 >2GMH-A nrPDB Length = 584 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 5/40 (12%) Query: 35 VIVVGAGMSGISAAKRLSEAGITD-----LLILEATDHIG 69 V++VGAG +G+SAA RL + + ++E HIG Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIG 77 >3FXO-A nrPDB Length = 390 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 135 DYVQKRIELADSVEEM-GEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYY 193 D+V+ R+E+ D +E++ E + L+ RD+MS++ + PN P + V Sbjct: 252 DFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF-----PNAPKVSPEAVKKEA 306 Query: 194 KFD 196 + D Sbjct: 307 ELD 309 >2X86-A nrPDB Length = 357 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 23/32 (71%), Gaps = 2/32 (6%) Query: 34 RVIVV--GAGMSGISAAKRLSEAGITDLLILE 63 R+I+V GAG G + K L++ GITD+L+++ Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVD 78 >5ZYN-B nrPDB Length = 471 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 32/53 (60%), Gaps = 1/53 (1%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN 81 A++ V+V+G+G++G++ + RL +++L+ IGG K + +GIN Sbjct: 1 ASMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKAS-SGIN 52 >4H7U-A nrPDB Length = 602 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 28/59 (47%) Query: 6 SFGLLAVAALLLALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEA 64 S LL + A++ L + V IV G G +G+ A RLSE +L++EA Sbjct: 14 SLALLGIQIARGAITYQHPDDLPSGVDYDFIVAGGGTAGLVVASRLSENSNWKVLVIEA 72 >3QJ4-A nrPDB Length = 342 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Query: 34 RVIVVGAGMSG--ISAAKRLSEAGITDLLILEATDHIGGRMHKT---NFAGINVELGANW 88 +V++VGAGM+G +A R +G L + + D GGRM + +LGA + Sbjct: 3 QVLIVGAGMTGSLCAALLRRQTSGPLYLAVWDKADDSGGRMTTACSPHNPQCTADLGAQY 62 Query: 89 V 89 + Sbjct: 63 I 63 >6FTI-5 nrPDB Length = 705 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 456 TGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKY 493 TG+H EH G + + + +L+NC KMC Y Sbjct: 608 TGKHIKEHDYYTPTGEFRVDREGSPVLLNCLMYKMCYY 645 >6B67-A nrPDB Length = 296 Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 6/49 (12%) Query: 135 DYVQKRIELADSVEEM-GEKLSATLHASGRDDMSILAMQRLNEHQPNGP 182 D+V+ R+E+ D +E++ E + L+ RD+MS++ + PN P Sbjct: 251 DFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF-----PNAP 294 >2LDB-A nrPDB Length = 317 Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 18/31 (58%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGITDLLIL 62 G RV+V+GAG G S L GI D ++L Sbjct: 6 GARVVVIGAGFVGASYVFALMNQGIADEIVL 36 >1ZOV-A nrPDB Length = 386 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 19/27 (70%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLI 61 VIVVGAG G++A L++ G+ LL+ Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLV 32 >1EQ2-A nrPDB Length = 310 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 20/29 (68%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILE 63 ++ GAG G + K L++ GITD+L+++ Sbjct: 3 IVTGGAGFIGSNIVKALNDKGITDILVVD 31 >1JWB-B nrPDB Length = 249 Score = 28.5 bits (62), Expect = 8.0, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 22/30 (73%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILE 63 RV++VG G G +A++ L+ AG+ +L +L+ Sbjct: 33 RVLIVGLGGLGCAASQYLASAGVGNLTLLD 62 >3ATQ-A nrPDB Length = 453 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 19/27 (70%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLI 61 V+++G G +G SAA +LS G+ LL+ Sbjct: 9 VLIIGGGFAGSSAAYQLSRRGLKILLV 35 >1QEZ-A nrPDB Length = 173 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 18/84 (21%) Query: 403 KMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVN-RYEYDQLRA--PVGRVYFTGEH 459 K+ PGK+ PD ++LV P G N +YEYD V RV +T + Sbjct: 2 KLSPGKNAPDVVNVLV--------------EIPQGSNIKYEYDDEEGVIKVDRVLYTSMN 47 Query: 460 TSEHYNGYVHGAYLSGIDSAEILI 483 +Y G++ G D ++L+ Sbjct: 48 YPFNY-GFIPGTLEEDGDPLDVLV 70 >2WD5-A nrPDB Length = 233 Score = 28.1 bits (61), Expect = 9.6, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 21/26 (80%), Gaps = 2/26 (7%) Query: 384 RIEQQ--SDEQTKAEIMQVLRKMFPG 407 RI++Q S +Q KAEIM+ +++++PG Sbjct: 28 RIDRQESSRQQRKAEIMESIKRLYPG 53 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3L1R-A nrPDB 636 0.0 1O5W-A nrPDB 453 e-127 2BXR-A nrPDB 452 e-127 1F8S-A nrPDB 421 e-118 1REO-A nrPDB 413 e-116 3KVE-A nrPDB 413 e-116 2BK5-A nrPDB 396 e-111 4FWE-A nrPDB 354 4e-98 3ABT-A nrPDB 273 1e-73 5L3D-A nrPDB 270 9e-73 3BI4-A nrPDB 257 7e-69 3NK2-X nrPDB 255 4e-68 3RHA-A nrPDB 190 2e-48 6CR0-A nrPDB 176 2e-44 2VVL-G nrPDB 167 8e-42 4IV9-A nrPDB 131 5e-31 Sequences not found previously or not previously below threshold: 2JB2-A nrPDB 119 3e-27 3X0V-A nrPDB 108 5e-24 3WE0-A nrPDB 104 1e-22 3LOV-A nrPDB 89 4e-18 3I6D-A nrPDB 82 6e-16 5MOG-A nrPDB 78 6e-15 1SEZ-A nrPDB 67 2e-11 4IVM-B nrPDB 60 3e-09 4DGK-A nrPDB 55 6e-08 4YRY-B nrPDB 52 7e-07 5NMX-A nrPDB 51 1e-06 5ZBC-A nrPDB 51 1e-06 2IVE-A nrPDB 51 1e-06 1I8T-A nrPDB 50 2e-06 4MO2-B nrPDB 48 7e-06 3K30-A nrPDB 46 3e-05 4ZCC-A nrPDB 46 3e-05 3KKJ-A nrPDB 46 4e-05 2UZZ-A nrPDB 45 6e-05 3KYB-A nrPDB 45 9e-05 2CVJ-A nrPDB 44 2e-04 4P9S-A nrPDB 43 3e-04 5JFC-L nrPDB 43 5e-04 5VJ7-A nrPDB 43 5e-04 5L46-A nrPDB 42 6e-04 3UP5-A nrPDB 42 6e-04 4REP-A nrPDB 42 7e-04 3UKH-A nrPDB 42 8e-04 5BR7-A nrPDB 41 9e-04 4RPJ-A nrPDB 41 0.001 4OVI-A nrPDB 41 0.001 1RP0-A nrPDB 41 0.001 4AP1-A nrPDB 40 0.002 3LXD-A nrPDB 40 0.002 2RGJ-A nrPDB 39 0.006 4YNU-A nrPDB 39 0.006 3ZZN-A nrPDB 39 0.006 2GV8-A nrPDB 38 0.009 1DOD-A nrPDB 38 0.010 3RP7-A nrPDB 38 0.010 2YR5-A nrPDB 38 0.010 4Y4M-A nrPDB 38 0.011 6BPY-A nrPDB 38 0.011 2LDB-A nrPDB 38 0.011 5W4C-A nrPDB 38 0.013 3IP1-A nrPDB 38 0.015 5XGV-A nrPDB 38 0.015 3FPZ-A nrPDB 37 0.016 5EQD-A nrPDB 37 0.017 1NAA-A nrPDB 37 0.018 3DIN-A nrPDB 37 0.020 3MJ4-A nrPDB 37 0.025 3ATQ-A nrPDB 37 0.025 4H7U-A nrPDB 36 0.028 2TMD-A nrPDB 36 0.029 4C5O-A nrPDB 36 0.029 3JSK-A nrPDB 36 0.029 2GAG-B nrPDB 36 0.036 4Y4N-A nrPDB 36 0.037 6DLL-A nrPDB 36 0.038 4UIR-A nrPDB 36 0.038 5TUK-A nrPDB 36 0.040 6C6P-A nrPDB 36 0.041 4TXK-A nrPDB 36 0.055 2BRY-A nrPDB 36 0.055 3BHF-A nrPDB 36 0.057 2QA2-A nrPDB 35 0.058 1NHQ-A nrPDB 35 0.060 1PS9-A nrPDB 35 0.070 1PJ5-A nrPDB 35 0.080 6CMZ-A nrPDB 35 0.085 6ER9-A nrPDB 35 0.090 2GMH-A nrPDB 35 0.090 4A6N-B nrPDB 35 0.092 3R9U-A nrPDB 34 0.11 3T14-A nrPDB 34 0.11 5TUM-A nrPDB 34 0.12 4CPD-A nrPDB 34 0.14 4RG3-A nrPDB 34 0.14 3QJ4-A nrPDB 34 0.14 5MJK-A nrPDB 34 0.16 5J7X-A nrPDB 34 0.17 6EJB-A nrPDB 34 0.18 1FOH-A nrPDB 34 0.19 2HQM-A nrPDB 34 0.21 1ZOV-A nrPDB 33 0.22 2Q7V-A nrPDB 33 0.24 2E5V-A nrPDB 33 0.24 2R9Z-A nrPDB 33 0.24 4JNQ-A nrPDB 33 0.26 2VOU-A nrPDB 33 0.26 4JDR-A nrPDB 33 0.28 1V59-A nrPDB 33 0.31 4X4J-A nrPDB 33 0.36 2YVG-A nrPDB 33 0.45 2A9F-A nrPDB 33 0.45 5Z70-A nrPDB 33 0.47 5UTH-A nrPDB 33 0.47 3IWA-A nrPDB 33 0.47 4K22-A nrPDB 32 0.50 6J0Z-C nrPDB 32 0.51 3IHG-A nrPDB 32 0.52 6JDK-A nrPDB 32 0.53 3WSV-A nrPDB 32 0.53 6IK8-B nrPDB 32 0.57 3ETC-A nrPDB 32 0.59 3ISH-A nrPDB 32 0.60 6BRD-A nrPDB 32 0.62 4GCM-A nrPDB 32 0.64 2ZBW-A nrPDB 32 0.65 5GSN-A nrPDB 32 0.66 5YGQ-A nrPDB 32 0.70 4YKF-A nrPDB 32 0.75 1FL2-A nrPDB 32 0.75 2VHY-A nrPDB 32 0.79 5JEA-H nrPDB 31 0.88 4OO1-H nrPDB 31 0.88 5NCC-A nrPDB 31 0.92 4Z2R-A nrPDB 31 0.96 5ZYN-B nrPDB 31 0.97 4MOP-A nrPDB 31 0.97 3AB1-A nrPDB 31 0.97 2A87-A nrPDB 31 0.97 5EZ7-A nrPDB 31 1.2 1GPE-A nrPDB 31 1.3 1GAL-A nrPDB 31 1.3 4B3J-A nrPDB 31 1.8 4HA6-A nrPDB 31 1.8 6HNS-A nrPDB 30 1.9 6GAR-A nrPDB 30 2.1 3CP8-A nrPDB 30 2.2 2VDC-G nrPDB 30 2.4 5KOX-A nrPDB 30 2.9 3PLN-A nrPDB 30 3.0 5IXB-A nrPDB 29 3.2 2EEZ-A nrPDB 29 3.2 5AVM-A nrPDB 29 3.4 3NTA-A nrPDB 29 3.9 5US9-A nrPDB 29 4.0 5TWC-A nrPDB 29 5.6 2QA1-A nrPDB 29 6.0 1L1J-A nrPDB 28 9.1 >3L1R-A nrPDB Length = 478 Score = 636 bits (1641), Expect = 0.0, Method: Composition-based stats. Identities = 471/472 (99%), Positives = 471/472 (99%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW 88 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW Sbjct: 1 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW 60 Query: 89 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE 148 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE Sbjct: 61 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE 120 Query: 149 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 208 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL Sbjct: 121 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 180 Query: 209 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI 268 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI Sbjct: 181 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI 240 Query: 269 KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTK 328 KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYT Sbjct: 241 KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTM 300 Query: 329 IFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ 388 IFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ Sbjct: 301 IFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ 360 Query: 389 SDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA 448 SDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA Sbjct: 361 SDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA 420 Query: 449 PVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD 500 PVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD Sbjct: 421 PVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD 472 >1O5W-A nrPDB Length = 534 Score = 453 bits (1164), Expect = e-127, Method: Composition-based stats. Identities = 105/472 (22%), Positives = 203/472 (43%), Gaps = 40/472 (8%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWVEGVN 93 V+V+G G+SG++AAK LSE I ++L+LEA D +GGR + + V++G +V Sbjct: 24 VVVIGGGISGLAAAKLLSEYKI-NVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQ 82 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGG---VYDEDYVQKRIELADSVEEM 150 + + T K+ Y+ Y G V++ L +++EM Sbjct: 83 NRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEM 142 Query: 151 GEKL--SATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 208 G+++ A A + + M+ L + + +F Y F VTS Sbjct: 143 GKEIPVDAPWQARHAQEWDKMTMKDLIDK--------ICWTKTAREFAYLFVNI-NVTSE 193 Query: 209 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYL--AGQYLKTDDKSGKIVD-------PRL 259 + V F +++V Q G A ++ + GQ K SG++ + ++ Sbjct: 194 PHEVSALWF------LWYV-RQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKV 246 Query: 260 QLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIY 319 +L+ V I + + V+T ++ Y YV+ SA +L + I FKP+LP + + I Sbjct: 247 KLSSPVTYIDQTDDNIIVETLNHEHYECKYVI-SAIPPILTAK-IHFKPELPPERNQLIQ 304 Query: 320 QFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANV--LLVTV 377 + M K + + FW K +++ + + PD ++ ++ + Sbjct: 305 RLPMGAVIKCMVYYKEAFW---KKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFI 361 Query: 378 TDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFS-NWPV 436 ++ R+ + + K +I ++ K+ ++ W +++ G ++ +P Sbjct: 362 LARKADRLAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPP 421 Query: 437 GVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQK 488 G+ +R PVGR+YF G T+ ++GY+ GA +G +A ++N K Sbjct: 422 GIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGK 473 >2BXR-A nrPDB Length = 527 Score = 452 bits (1161), Expect = e-127, Method: Composition-based stats. Identities = 98/472 (20%), Positives = 199/472 (42%), Gaps = 40/472 (8%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGI-NVELGANWVEGVN 93 V+V+G G+SG+SAAK L+E G++ +L+LEA D +GGR + + V++G +V Sbjct: 16 VVVIGGGISGLSAAKLLTEYGVS-VLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQ 74 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGG---VYDEDYVQKRIELADSVEEM 150 + + T K+ Y+ Y G V++ L +++ M Sbjct: 75 NRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNM 134 Query: 151 GEKL--SATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 208 G+++ A A D + M+ L + + +F Y F VTS Sbjct: 135 GKEIPTDAPWEAQHADKWDKMTMKELIDK--------ICWTKTARRFAYLFVNI-NVTSE 185 Query: 209 QNTVPLATFSDFGDDVYFVADQRGYEAVVYYL---------AGQYLKTDDKSGKIVDPRL 259 + V F +++V Q G ++ + G + ++ ++ ++ Sbjct: 186 PHEVSALWF------LWYV-KQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQV 238 Query: 260 QLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIY 319 +LN V + S + ++T ++ Y YV+ +A L + I F+P+LP + + I Sbjct: 239 KLNHPVTHVDQSSDNIIIETLNHEHYECKYVI-NAIPPTLTAK-IHFRPELPAERNQLIQ 296 Query: 320 QFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANV--LLVTV 377 + M K + + FW K +++ + + PD ++ ++ + Sbjct: 297 RLPMGAVIKCMMYYKEAFW---KKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFI 353 Query: 378 TDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFS-NWPV 436 ++ R+ + E K +I ++ K+ ++ W +++ G ++ +P Sbjct: 354 LARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPP 413 Query: 437 GVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQK 488 G+ +R PVGR++F G T+ ++GY+ GA +G +A ++N K Sbjct: 414 GIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGK 465 >1F8S-A nrPDB Length = 498 Score = 421 bits (1082), Expect = e-118, Method: Composition-based stats. Identities = 122/512 (23%), Positives = 211/512 (41%), Gaps = 74/512 (14%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 L +A++G L AT P+ V++VGAGM+G+SAA L+ AG + +LEA++ GGR+ Sbjct: 20 LEIARNG-LKATSNPKHVVIVGAGMAGLSAAYVLAGAG-HQVTVLEASERPGGRVRTYRN 77 Query: 78 AGINVELGANWVEGVNGGKMNPIWPIVNS-----TLKLRNFRSDFD---YLAQNVYKEDG 129 A W + ++ IV L+L F + D Y +N+ K+ G Sbjct: 78 EE------AGWYANLGPMRLPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVG 131 Query: 130 GVYDED----YVQKRIELADSVEEM-GEKLSATLHASGRDDMSILAMQRLNEHQ------ 178 V + Y K E S ++ E L + R + S + LN++ Sbjct: 132 EVKKDPGLLKYPVKPSEAGKSAGQLYEESLGKVVEELKRTNCSYI----LNKYDTYSTKE 187 Query: 179 ---PNGPATP--VDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGY 233 G +P VDM+ D D + + SL++ DD++ Y Sbjct: 188 YLIKEGDLSPGAVDMIGDLLNEDSGY-YVSFIESLKH-----------DDIF------AY 229 Query: 234 EAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVK----TEDNSVYSADY 289 E + K + + ++ N V +I+ + VTV +++ +ADY Sbjct: 230 EKRFDEIVDGMDKLPTAMYRDIQDKVHFNAQVIKIQQNDQKVTVVYETLSKETPSVTADY 289 Query: 290 VMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEG--KGREFF 347 V+V + ++ LI+F P L K A+ TKIFL KFW + G + Sbjct: 290 VIVCTTSRAVR--LIKFNPPLLPKKAHALRSVHYRSGTKIFLTCTTKFWEDDGIHGGKST 347 Query: 348 LYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIM---QVLRKM 404 SR YY + + +++ + Q D + A+I+ L Sbjct: 348 TDLPSRFIYYP-----NHNFTNGVGVIIAYGIGDDANFFQALDFKDCADIVFNDLSLIHQ 402 Query: 405 FPGKDVPD-ATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEH 463 P KD+ ++ +W D++ G + + ++ D L A GR+YF GE+T++ Sbjct: 403 LPKKDIQSFCYPSVIQKWSLDKYAMGGITTFTPYQFQHFSDPLTASQGRIYFAGEYTAQA 462 Query: 464 YNGYVHGAYLSGIDSAEILINCAQKKMCKYHV 495 + G++ SG+ +A +N A + H+ Sbjct: 463 H-GWIDSTIKSGLRAARD-VNLASENPSGIHL 492 >1REO-A nrPDB Length = 486 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 124/506 (24%), Positives = 211/506 (41%), Gaps = 74/506 (14%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 L +A++G L AT P+ V+VVGAGMSG+SAA LS AG + +LEA++ GGR+ Sbjct: 20 LEIARNG-LKATSNPKHVVVVGAGMSGLSAAYVLSGAG-HQVTVLEASERAGGRVRTYRN 77 Query: 78 AGINVELGANWVEGVNGGKMNPIWPIVNS-----TLKLRNFRSDFD---YLAQNVYKEDG 129 +W + ++ IV L+L F + D Y +N+ K G Sbjct: 78 D------KEDWYANLGPMRLPEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVG 131 Query: 130 GVYDED----YVQKRIELADSVEEM-GEKLSATLHASGRDDMSILAMQRLNEHQ------ 178 V + Y K E S ++ E L + R + S + LN++ Sbjct: 132 EVKKDPGVLKYPVKPSEEGKSAGQLYEESLGKVVEELKRTNCSYI----LNKYDTYSTKE 187 Query: 179 ---PNGPATP--VDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGY 233 G +P VDM+ D D + SL++ DD++ Y Sbjct: 188 YLLKEGNLSPGAVDMIGDLMNEDSGY-YVSFPESLRH-----------DDIF------AY 229 Query: 234 EAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTV----KTEDNSVYSADY 289 E + G K + ++ ++ LN V +I+ + VTV ++ + +ADY Sbjct: 230 EKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTADY 289 Query: 290 VMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEG--KGREFF 347 V+V + + I+F+P LP K A+ TKIFL +KFW + G + Sbjct: 290 VIVCTTSRATRR--IKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGKST 347 Query: 348 LYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIM---QVLRKM 404 SR YY + +++ + Q D + A+I+ L Sbjct: 348 TDLPSRFIYYP-----NHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVINDLSLIHQ 402 Query: 405 FPGKDVPD-ATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEH 463 P +++ ++ +W D++ G + + ++ + L A V R+YF GEHT+E Sbjct: 403 LPREEIQTFCYPSMIQKWSLDKYAMGGITTFTPYQFQHFSESLTASVDRIYFAGEHTAEA 462 Query: 464 YNGYVHGAYLSGIDSAEILINCAQKK 489 + G++ SG+ +A +N A ++ Sbjct: 463 H-GWIDSTIKSGLRAARD-VNRASEQ 486 >3KVE-A nrPDB Length = 486 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 117/502 (23%), Positives = 210/502 (41%), Gaps = 66/502 (13%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNF 77 L +A++G L T P+ V+VVGAGMSG+SAA L+ AG + +LEA++ GGR+ Sbjct: 20 LEIARNG-LKKTSNPKHVVVVGAGMSGLSAAYVLAGAG-HKVTVLEASERAGGRVRTHRN 77 Query: 78 AGINVELGANWVEGVNGGKMNPIWPIVNS-----TLKLRNFRSDFD---YLAQNVYKEDG 129 + W + ++ IV L L F + D Y +N+ K G Sbjct: 78 S------KEGWYANLGPMRIPEKHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVG 131 Query: 130 GV-YDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQ---------P 179 V D ++ ++ ++ + G+ +L ++ +D LN++ Sbjct: 132 EVNKDPGLLKYPVKPSEEGKSAGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIK 191 Query: 180 NGPATP--VDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVV 237 G +P VDM+ D D + + SL++ DD++ YE Sbjct: 192 EGNLSPGAVDMIGDLLNEDSGY-YVSFIESLKH-----------DDIF------AYEKRF 233 Query: 238 YYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVK----TEDNSVYSADYVMVS 293 + G + + ++ +++ N V +I+ + VTV +D S +ADYV+V Sbjct: 234 DEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVC 293 Query: 294 ASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEG--KGREFFLYAS 351 + + IQF+P LP K A+ TKIFL KFW + G + Sbjct: 294 TTSRAARR--IQFEPPLPPKKQHALRSVHYRSGTKIFLTCSSKFWEDDGIHGGKSTTDLP 351 Query: 352 SRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIM---QVLRKMFPGK 408 SR YY + +++ + Q + A+I+ L P + Sbjct: 352 SRFIYYP-----NHNFSTGVGVIIAYGIGDDANFFQALKFKDCADIVFNDLSLIHQLPKE 406 Query: 409 DVPD-ATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGY 467 ++ ++ +W D++ G + + + + L AP GR++F GE+T+E + G+ Sbjct: 407 EIQSFCYPSMIQKWSLDKYAMGAITTFTPYQFQRFSEALTAPQGRIFFAGEYTAEAH-GW 465 Query: 468 VHGAYLSGIDSAEILINCAQKK 489 + SG+ +A +N A ++ Sbjct: 466 IDSTIKSGLTAARD-VNRASEQ 486 >2BK5-A nrPDB Length = 520 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 85/467 (18%), Positives = 189/467 (40%), Gaps = 40/467 (8%) Query: 42 MSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWVEGVNGGKMNPI 100 +SG++AAK L ++G+ ++++LEA D +GGR + + V+LG ++V + Sbjct: 14 ISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLA 72 Query: 101 WPIVNSTLKLRNFRSDFDYLAQNVYKEDGG---VYDEDYVQKRIELADSVEEMGEKL--S 155 + T K+ ++ Y G V++ ++++MG ++ Sbjct: 73 KELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSD 132 Query: 156 ATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLA 215 A A ++ + M+ L + + F VT+ + V Sbjct: 133 APWKAPLAEEWDNMTMKELLDKL--------CWTESAKQLATLFV-NLCVTAETHEVSAL 183 Query: 216 TFSDFGDDVYFVADQRGYEAVVYY---------LAGQYLKTDDKSGKIVDPRLQLNKVVR 266 F +++V Q G ++ G + ++ ++ R++L + V Sbjct: 184 WF------LWYV-KQCGGTTRIFSTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVI 236 Query: 267 EIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVY 326 I + V V+T ++ +Y A YV+ + + I F P LP + + I + + Sbjct: 237 YIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMK--IHFNPPLPMMRNQMITRVPLGSV 294 Query: 327 TKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDAN--VLLVTVTDEESRR 384 K + + FW + +++ V + P+ N ++ + ++R+ Sbjct: 295 IKCIVYYKEPFW---RKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARK 351 Query: 385 IEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNW-PVGVNRYEY 443 + + + E+ ++ ++ K+ + + W +++ G ++ + P G+ Sbjct: 352 LARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYG 411 Query: 444 DQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKM 490 LR PV R+YF G T+ H++GY+ GA +G +A +++ K Sbjct: 412 RVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIP 458 >4FWE-A nrPDB Length = 796 Score = 354 bits (909), Expect = 4e-98, Method: Composition-based stats. Identities = 135/478 (28%), Positives = 212/478 (44%), Gaps = 67/478 (14%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK-TNFAGINVELGANWVE 90 VI++GAG +G++AA++L GI + +LEA D IGGR+ +F G+ V GA + Sbjct: 356 NKSVIIIGAGPAGLAAARQLHNFGIK-VTVLEAKDRIGGRVWDDKSFKGVTVGRGA---Q 411 Query: 91 GVNGGKMNPIWPIVNS-TLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIE-----LA 144 VNG NP+ + + + F D + ++GG + + KR++ L Sbjct: 412 IVNGCINNPVALMCEQLGISMHKFGERCDLI------QEGGRITDPTIDKRMDFHFNALL 465 Query: 145 DSVEE------------MGEKLSATLHASGRDD---MSILAMQRLNEHQPNGPATPVDMV 189 D V E +GEK+ A ++ S L Q L H N Sbjct: 466 DVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSN--------- 516 Query: 190 VDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDD 249 +Y S ++ F+ F D + GY ++ LA Sbjct: 517 -----LEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTP--GYSVIIEKLAEGLD---- 565 Query: 250 KSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPK 309 +QL V+ I YS V V T D + YSA V+V+ L +LQ IQF P Sbjct: 566 ---------IQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPP 616 Query: 310 LPTWKVRAIYQFDMAVYTKIFLKFPRKFW-PEGKGREFFLYAS---SRRGYYGVWQEFEK 365 L K++AI + KI L+FP +FW + +G +FF + S+RG + V+ + + Sbjct: 617 LSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDP 676 Query: 366 QYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDR 425 Q +VL+ + E + D+Q + M LR++F ++VPD T V RW +D Sbjct: 677 QK-KHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDP 735 Query: 426 FYKGTFSNWPVGVNRYEYDQLRAPV-GRVYFTGEHTSEHYNGYVHGAYLSGIDSAEIL 482 + + +S G + YD + + G V+F GE T+ H+ V GAYLSG+ A + Sbjct: 736 WIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 793 >3ABT-A nrPDB Length = 662 Score = 273 bits (698), Expect = 1e-73, Method: Composition-based stats. Identities = 102/418 (24%), Positives = 160/418 (38%), Gaps = 66/418 (15%) Query: 96 KMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDE-----DYVQKRIELADSVEEM 150 + ++N + L+ + YKE V +++ K + + Sbjct: 266 TQEELKELLNKMVNLKEKIKEL----HQQYKEASEVKPPRDITAEFLVKSKH--RDLTAL 319 Query: 151 GEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQN 210 ++ G+ ++L E + N P+ D D+ FA N Sbjct: 320 CKEYDELAETQGK------LEEKLQELEANPPSDVYLSSRDRQILDWHFAN----LEFAN 369 Query: 211 TVPLATFS----DFGDDVYFVAD----QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLN 262 PL+T S D DD F + GY V LA ++LN Sbjct: 370 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLD-------------IKLN 416 Query: 263 KVVREIKYSPGGVTV------KTEDNSVYSADYVMVSASLGVL--QSDLIQFKPKLPTWK 314 VR+++Y+ G V T +Y D V+ + LGVL Q +QF P LP WK Sbjct: 417 TAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWK 476 Query: 315 VRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLL 374 A+ + K+ L F R FW F + S G F Y A +LL Sbjct: 477 TSAVQRMGFGNLNKVVLCFDRVFW--DPSVNLFGHVGSTTASRGELFLFWNLY-KAPILL 533 Query: 375 VTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNW 434 V E + +E SD+ + +L+ +F VP + +V RW +D + +G++S Sbjct: 534 ALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYV 593 Query: 435 PVGVNRYEYDQLRAPVG-------------RVYFTGEHTSEHYNGYVHGAYLSGIDSA 479 G + +YD + P+ R++F GEHT +Y VHGA LSG+ A Sbjct: 594 AAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 651 Score = 112 bits (279), Expect = 4e-25, Method: Composition-based stats. Identities = 48/258 (18%), Positives = 99/258 (38%), Gaps = 32/258 (12%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 +VI++G+G+SG++AA++L G+ D+ +LEA D +GGR+ +LGA V G+ Sbjct: 109 KVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 167 Query: 94 GGKMNPIWPIVNSTL-KLRNFRSDFDYLAQNVYKEDGGVYDEDYVQ-------------- 138 G M + VN L K++ ++ Q V KE + ++++ + Sbjct: 168 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDF 227 Query: 139 -----KRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYY 193 K + L ++E + + + + + + E V++ Sbjct: 228 NVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIV--KTQEELKELLNKMVNLKEKIK 285 Query: 194 KFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGK 253 + ++ E V ++ D+ LA K ++K + Sbjct: 286 ELHQQYKEASEVKPPRDITAEFLVKSKHRDLT------ALCKEYDELAETQGKLEEKLQE 339 Query: 254 I---VDPRLQLNKVVREI 268 + + L+ R+I Sbjct: 340 LEANPPSDVYLSSRDRQI 357 >5L3D-A nrPDB Length = 852 Score = 270 bits (690), Expect = 9e-73, Method: Composition-based stats. Identities = 97/414 (23%), Positives = 155/414 (37%), Gaps = 58/414 (14%) Query: 96 KMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDE-----DYVQKRIELADSVEEM 150 + ++N + L+ + YKE V +++ K + + Sbjct: 437 TQEELKELLNKMVNLKEKIKEL----HQQYKEASEVKPPRDITAEFLVKSKH--RDLTAL 490 Query: 151 GEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQN 210 ++ G+ ++L E + N P+ D D+ FA + Sbjct: 491 CKEYDELAETQGK------LEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPL 544 Query: 211 TVPLATFSDFGDDVYFVAD----QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVR 266 + D DD F + GY V LA ++LN VR Sbjct: 545 STLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLD-------------IKLNTAVR 591 Query: 267 EIKYSPGGVTV------KTEDNSVYSADYVMVSASLGVL--QSDLIQFKPKLPTWKVRAI 318 +++Y+ G V T +Y D V+ + LGVL Q +QF P LP WK A+ Sbjct: 592 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV 651 Query: 319 YQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVT 378 + K+ L F R FW F + S G F Y A +LL V Sbjct: 652 QRMGFGNLNKVVLCFDRVFW--DPSVNLFGHVGSTTASRGELFLFWNLY-KAPILLALVA 708 Query: 379 DEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGV 438 E + +E SD+ + +L+ +F VP + +V RW +D + +G+ S G Sbjct: 709 GEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSHSYVAAGS 768 Query: 439 NRYEYDQLRAPVG-------------RVYFTGEHTSEHYNGYVHGAYLSGIDSA 479 + +YD + P+ R++F GEHT +Y VHGA LSG+ A Sbjct: 769 SGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 Score = 112 bits (279), Expect = 4e-25, Method: Composition-based stats. Identities = 45/241 (18%), Positives = 93/241 (38%), Gaps = 29/241 (12%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 +VI++G+G+SG++AA++L G+ D+ +LEA D +GGR+ +LGA V G+ Sbjct: 280 KVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 338 Query: 94 GGKMNPIWPIVNSTL-KLRNFRSDFDYLAQNVYKEDGGVYDEDYVQ-------------- 138 G M + VN L K++ ++ Q V KE + ++++ + Sbjct: 339 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDF 398 Query: 139 -----KRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYY 193 K + L ++E + + + + + + E V++ Sbjct: 399 NVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIV--KTQEELKELLNKMVNLKEKIK 456 Query: 194 KFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGK 253 + ++ E V ++ D+ LA K ++K + Sbjct: 457 ELHQQYKEASEVKPPRDITAEFLVKSKHRDLT------ALCKEYDELAETQGKLEEKLQE 510 Query: 254 I 254 + Sbjct: 511 L 511 >3BI4-A nrPDB Length = 516 Score = 257 bits (657), Expect = 7e-69, Method: Composition-based stats. Identities = 112/532 (21%), Positives = 195/532 (36%), Gaps = 116/532 (21%) Query: 30 TVGP---RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK-TNFAGINVELG 85 TV P +VI++GAG++G+ AA L + GI D L+LEA D +GGR+ T + G ++G Sbjct: 3 TVSPAKKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIG 62 Query: 86 ANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQN-VY-KEDGGVYDEDYVQKRIEL 143 A+W NP++ + + L L + R+ F + N +Y E+ G D D + +E+ Sbjct: 63 ASWHHDT---LTNPLF-LEEAQLSLNDGRTRFVFDDDNFIYIDEERGRVDHDK-ELLLEI 117 Query: 144 ADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPP 203 D ++MS A ++H + +V+ Y +F Sbjct: 118 VD------------------NEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLTND 159 Query: 204 RVTSLQN-------TVPLATFSDFGDDVYFVADQR-----GYEAVVYYLAGQYLKTDDKS 251 ++ L L D YF R Y++VV +A + + Sbjct: 160 QIRYLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQN---- 215 Query: 252 GKIVDPRLQLNKVVREIKYSPG-GVTVKTEDNSVYSADYVMVSASLGVLQ---------S 301 L+L+ V+ I P VTV ED +VY+ADYV+++ VL Sbjct: 216 ------WLKLSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLR 269 Query: 302 DLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGR----------------- 344 I+F+P L A + K+ +F W + Sbjct: 270 GRIEFQPPLKPVIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRN 329 Query: 345 --------------EFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSD 390 + + S ++ + ++ + + IE + Sbjct: 330 AENLDELDSMLEREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIRE 389 Query: 391 EQTK-----AEIMQVLRKMFPGKDVPDAT---------------DILVPRWWSDRFYKGT 430 ++ + ++ + K +DV D +I+V W D + +G Sbjct: 390 DKERLFSFFQPVLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGA 449 Query: 431 FSNWPVGVNRYEYDQLRAPVG---RVYFTGEHTSEHYNGYVHGAYLSGIDSA 479 +S G + + + G R+ F GEHT G +GA+ SG A Sbjct: 450 YSACFPGDDPVDM-VVAMSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREA 500 >3NK2-X nrPDB Length = 431 Score = 255 bits (650), Expect = 4e-68, Method: Composition-based stats. Identities = 99/466 (21%), Positives = 168/466 (36%), Gaps = 63/466 (13%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKT---NFAGINVELGANWVEG 91 IVVG G SG+ AA+ L+ AG +L+LE + +GGR + N G+ VE+G ++ Sbjct: 4 AIVVGGGFSGLKAARDLTNAG-KKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLHR 62 Query: 92 VNGGKMN-PIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEM 150 + ++ + T F S L D+ + E Sbjct: 63 KHHPRLAAELDRYGIPTAAASEFTSFRHRLGPTA-------VDQAFPIPGSEAV------ 109 Query: 151 GEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQN 210 + A + RD I + L P++ VD + Sbjct: 110 --AVEAATYTLLRDAHRIDLEKGLENQDLEDLDIPLNEYVDKLDLPPV---SRQFLLAWA 164 Query: 211 TVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDD----KSGKIVD------PRLQ 260 L +D ++ + + Y + G L D+ S +VD P ++ Sbjct: 165 WNMLGQPADQASALWMLQLVAAHH---YSILGVVLSLDEVFSNGSADLVDAMSQEIPEIR 221 Query: 261 LNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQ 320 L VV I S V V +D + A V+V+ + + I F P LP + I + Sbjct: 222 LQTVVTGIDQSGDVVNVTVKDGHAFQAHSVIVATPMNTWRR--IVFTPALPERRRSVIEE 279 Query: 321 FDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDE 380 KI + +G E + + ++ E ++ LLV TD Sbjct: 280 GHGGQGLKILIHV--------RGAEAGIECVGDGIFPTLYDYCEVS--ESERLLVAFTDS 329 Query: 381 ESRRIEQQSDEQTKAEIMQVLRKM-FPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVN 439 S + K ++ L ++ G D D W +D ++G + VG Sbjct: 330 GS--FDPTDIGAVKDAVLYYLPEVEVLGIDYHD--------WIADPLFEGPWVAPRVGQF 379 Query: 440 RYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINC 485 + +L P GR++F G S + GY+ GA +++AE +N Sbjct: 380 SRVHKELGEPAGRIHFVGSDVSLEFPGYIEGA----LETAECAVNA 421 >3RHA-A nrPDB Length = 482 Score = 190 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 86/462 (18%), Positives = 171/462 (37%), Gaps = 31/462 (6%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 V++VGAG SG++AA+ L +AG++ + +LEA D +GGR G +E+G WV Sbjct: 10 VVIVGAGPSGLTAARELKKAGLS-VAVLEARDRVGGRTWTDTIDGAMLEIGGQWVSPDQT 68 Query: 95 GKMNPIWPIVNSTLK-LRNFRSDFDYLAQNVYKEDGGV--YDEDYVQKRIELADSVEEMG 151 M + + R+ S + + G +E + +L ++E+ Sbjct: 69 VLMELLDELGLKMYSRYRDGESVYIGADGKRTQYTGDTFPVNETTKAEMDKLVAILDELA 128 Query: 152 EKLS--ATLHASGRDDMSILA-----MQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPR 204 ++ ++ ++ Q N+ + K + F+ Sbjct: 129 AEIGPTEPWAHPKARELDTISFHHWLRQNSNDEEACNNIGLFIAGGMLTKPAHAFSALQA 188 Query: 205 VTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKV 264 V + + +D F+ D+R + G + + + LN Sbjct: 189 VLMAASAGSFSHLTDED----FILDKR--------VIGGMQQVSLLQAAELGDDVVLNSP 236 Query: 265 VREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMA 324 VR IK+ GV+V +E +V +A +V+++ + + F P LP + + + Sbjct: 237 VRTIKWDENGVSVVSERATV-NARFVIMAVPPNLYSR--VSFDPPLPRRQHQMHQHQSLG 293 Query: 325 VYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRR 384 + K+ + FW E S + L+ V+DE++ Sbjct: 294 LVIKVHAVYDTPFWREE---GLSGTGFSAGALVQEVYDNTNHGDSRGTLVGFVSDEKADA 350 Query: 385 IEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTF-SNWPVGVNRYEY 443 + + S E K I++ + K W S+ + +G + S++ +G Sbjct: 351 VFELSAEDRKKAILESIAGFLGDK-ALTPEVYYESDWGSEEWTRGAYASSYDLGGLHRYG 409 Query: 444 DQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINC 485 A VG +Y++ + +V GA G +A ++ Sbjct: 410 KDQHANVGPIYWSSSDLAAEGYQHVDGAVRMGQATAARIVEA 451 >6CR0-A nrPDB Length = 440 Score = 176 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 85/456 (18%), Positives = 151/456 (33%), Gaps = 34/456 (7%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 IVVGAG SG+ AA+ LS G + +LI+EA +GGR H NF G VE+G V Sbjct: 11 AIVVGAGFSGLVAARELSAQGRS-VLIIEARHRLGGRTHVVNFLGRPVEIGGAGVHWCQP 69 Query: 95 GKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYD-EDYV---QKRIELADSVEEM 150 + + D + DG D + Sbjct: 70 HVFAEMQRY---GFGFKE-APLADLDKAYMVFADGQKIDVPPATFDEEYTTAFEKFCSRS 125 Query: 151 GEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQN 210 E ++S L +H + + + + P S + Sbjct: 126 RELFPRPYSPLDNHEVSNLDGVSARDHLESLGLNELQLASMNAELTLYGGAPTTELSYPS 185 Query: 211 TVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKY 270 V + + D + F ++ Y ++ G + V + Sbjct: 186 FVKFHALASW-DTITFTDSEKRY-----HVQGGTNALCQAIFDDCRADSEFGVPVEAVAQ 239 Query: 271 SPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIF 330 + GVTV D V+ A + +L ++F+P LP K I +MA +++ Sbjct: 240 TDNGVTVTLADKRVFRA--LTCVLTLPTKVYADVRFEPPLPPEKRAFIEHAEMADGAELY 297 Query: 331 LKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSD 390 + + F + + V +L +T+ + +E Sbjct: 298 VHVRQNL------GNTFTFCDDPNPFNAVQTYAYDDEL-GTILKITIGRQSLINLENFD- 349 Query: 391 EQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPV 450 I +RK+ +V +A W D + + ++ G D + P Sbjct: 350 -----AIAAEIRKIHGDVEVLEALPY---NWAMDEYARTSYPAMRKGWFSRYKD-MAKPE 400 Query: 451 GRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCA 486 R++F G T++ ++ Y+ GA SGI + + Sbjct: 401 NRLFFAGSATADGWHEYIDGAIESGIRVGREIRHFM 436 >2VVL-G nrPDB Length = 495 Score = 167 bits (423), Expect = 8e-42, Method: Composition-based stats. Identities = 86/481 (17%), Positives = 150/481 (31%), Gaps = 60/481 (12%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 VIV+G G G++A + L+ AG L+LEA D IGGR +N G E+G WV Sbjct: 42 VIVIGGGYCGLTATRDLTVAGFKT-LLLEARDRIGGRSWSSNIDGYPYEMGGTWVHWHQS 100 Query: 95 GKMNPI--WPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGE 152 I + + N+ NF ++ + EL S Sbjct: 101 HVWREITRYKMHNALSPSFNFSRGVNHFQLRTNPTTSTYMTHEAED---ELLRSALHKFT 157 Query: 153 KLSATLHASGRD-DMSILAMQRLNEHQPNGPATPVDMVVDYYKFDY-------------E 198 + T + + + ++ + +D + D + Sbjct: 158 NVDGTNGRTVLPFPHDMFYVPEFRKYDEMSYSERIDQIRDELSLNERSSLEAFILLCSGG 217 Query: 199 FAEPPRVTSLQNTVPLATFSDFG-----DDVYFVADQRGYEAVVYYLAGQYLKTDDKSGK 253 E + ++ ++ G F Q + + A + G Sbjct: 218 TLENSSFGEFLHWWAMSGYTYQGCMDCLMSYKFKDGQSAFARRFWEEAAGTGRLGYVFG- 276 Query: 254 IVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTW 313 VR + V D + A V+ + L VL IQF P L T Sbjct: 277 ---------CPVRSVVNERDAARVTARDGREFVAKRVVCTIPLNVL--STIQFSPALSTE 325 Query: 314 KVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASS-RRGYYGVWQEF----EKQYP 368 ++ A+ +++ TK+ + K S Y + + P Sbjct: 326 RISAMQAGHVSMCTKVHAEVDNK------------DMRSWTGIAYPFNKLCYAIGDGTTP 373 Query: 369 DANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYK 428 N LV + + + +T + Q+ F K + + W D F K Sbjct: 374 AGNTHLVCFGTDANHIQPDEDVRETLKAVGQLAPGTFGVKRL------VFHNWVKDEFAK 427 Query: 429 GTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQK 488 G + G+ LR G V F + + ++ GA G +A +++ Sbjct: 428 GAWFFSRPGMVSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVLEELGT 487 Query: 489 K 489 K Sbjct: 488 K 488 >4IV9-A nrPDB Length = 557 Score = 131 bits (330), Expect = 5e-31, Method: Composition-based stats. Identities = 99/522 (18%), Positives = 175/522 (33%), Gaps = 68/522 (13%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAG----INVE 83 A T PRV +VGAG+SG+ AA L AG+ D+++ E+ D IGGR+ F E Sbjct: 34 AGTPTPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAE 93 Query: 84 LGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIEL 143 +GA G + + + D + ++ G Y +K EL Sbjct: 94 MGAMRFPPSATGLFHYLKKF---GISTSTTFPDPGVVDTELH-YRGKRYHWPAGKKPPEL 149 Query: 144 ADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPA--TPVDMVVDYYKFDYEFAE 201 V E + L + S++A + +G + F Sbjct: 150 FRRVYEGWQSL--LSEGYLLEGGSLVAPLDITAMLKSGRLEEAAIAWQGWLNVFRDCSFY 207 Query: 202 PPRVTSLQNTVP-------------LATFSDFGDDVYFVADQRGYEAVVYYLAGQY---- 244 V P L G + Q G+ ++ + Y Sbjct: 208 NAIVCIFTGRHPPGGDRWARPEDFELFGSLGIGSGGFLPVFQAGFTEILRMVINGYQSDQ 267 Query: 245 -------------LKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVM 291 L GK + R+ ++ V I + ++TE D V+ Sbjct: 268 RLIPDGISSLAARLADQSFDGKALRDRVCFSR-VGRISREAEKIIIQTEAGEQRVFDRVI 326 Query: 292 VSASLGVLQS--DLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLY 349 V++S +Q L + L RA+ + + +K+F+ KFW + K Sbjct: 327 VTSSNRAMQMIHCLTDSESFLSRDVARAVRETHLTGSSKLFILTRTKFWIKNK---LPTT 383 Query: 350 ASSRRGYYGVW-QEFEKQYPD-ANVLLVTVTDEESRR--IEQQSDEQTKAEIMQVLRKMF 405 S GV+ +++ P+ V+L++ T E+ + + + ++ L + Sbjct: 384 IQSDGLVRGVYCLDYQPDEPEGHGVVLLSYTWEDDAQKMLAMPDKKTRCQVLVDDLAAIH 443 Query: 406 PG-KDVPDATDILVPR------WWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGR------ 452 P D R W +D G F G + Y P+ Sbjct: 444 PTFASYLLPVDGDYERYVLHHDWLTDPHSAGAFKLNYPGEDVYSQRLFFQPMTANSPNKD 503 Query: 453 --VYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCK 492 +Y G S G++ GA + ++SA ++ ++ K Sbjct: 504 TGLYLAGCSCSFA-GGWIEGAVQTALNSACAVLRSTGGQLSK 544 >2JB2-A nrPDB Length = 489 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 79/495 (15%), Positives = 164/495 (33%), Gaps = 40/495 (8%) Query: 25 GSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 G + + V+V+G G +G+ +A L +AG + +LEA GGR+ +L Sbjct: 6 GKVKGSHS--VVVLGGGPAGLCSAFELQKAGYK-VTVLEARTRPGGRVWTARGGSEETDL 62 Query: 85 GAN---------WVEGVNGGKMNPIWPIVN--STLKLRNFRSDFDYLAQNVYKEDGGVYD 133 V ++ ++ L + V + Sbjct: 63 SGETQKCTFSEGHFYNVGATRIPQSHITLDYCRELGVEIQGFGNQNANTFVNYQSDTSLS 122 Query: 134 EDYVQKRIELADSVEEMGEKL------SATLHASGRDDMSILAMQRLNEHQPNGPATPVD 187 V R AD+ M E L A R+D L+ + + + Sbjct: 123 GQSVTYRAAKADTFGYMSELLKKATDQGALDQVLSREDKDALSEFLSDFGDLSDDGRYLG 182 Query: 188 MVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKT 247 Y + + S G + F + + G Sbjct: 183 SSRRGYDSEPGAGLNFGTEKKPFAMQEVIRSGIGRNFSFDFGYDQAMMMFTPVGGMDRIY 242 Query: 248 DDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDN---SVYSADYVMVSASLGVLQSDLI 304 +I + V +K GVTV+ +ADY + + ++ Sbjct: 243 YAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTIPPHLVGR--- 299 Query: 305 QFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFE 364 + LP + A+ + K+ +++ R++W + R + +++ + + ++ Sbjct: 300 -LQNNLPGDVLTALKAAKPSSSGKLGIEYSRRWWET-EDRIYGGASNTDKDISQIMFPYD 357 Query: 365 KQYPDANVLLVTVTDEE-SRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWS 423 D V++ + + E + Q A+ + ++ K D + W Sbjct: 358 HYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEGSEIHGEKYTRDISSSFSGSWRR 417 Query: 424 DRFYKGTFSNW------PVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGID 477 ++ + ++NW G EY++L PV ++YF G+H S + HGA + Sbjct: 418 TKYSESAWANWAGSGGSHGGAATPEYEKLLEPVDKIYFAGDHLSNAI-AWQHGA----LT 472 Query: 478 SAEILINCAQKKMCK 492 SA ++ +++ + Sbjct: 473 SARDVVTHIHERVAQ 487 >3X0V-A nrPDB Length = 541 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 85/490 (17%), Positives = 159/490 (32%), Gaps = 56/490 (11%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLL--ILEATDHIGGRMHKTNF---AGINVELGANW 88 +V +VGAG+SG+ A L + I +L I E++ GGR++ +F ++GA Sbjct: 9 KVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFTDAKHDYYDIGAMR 68 Query: 89 VEGVNGGK--MNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYV------QKR 140 + K N +K + L N + GV D V Sbjct: 69 YPDIPSMKRTFNLFKRTGMPLIKYYLDGENTPQLYNNHF-FAKGVVDPYMVSVANGGTVP 127 Query: 141 IELADSVEEMGEKLSATLHASGRDDMSI-----------LAMQRLNEHQPNGPATPVDMV 189 ++ DSV E ++ +D + L P G A D Sbjct: 128 DDVVDSVGEKLQQAFGYYKEKLAEDFDKGFDELMLVDDMTTREYLKRGGPKGEAPKYDFF 187 Query: 190 VDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDD 249 + + +V + D + + G +V + + Sbjct: 188 AIQWMETQNTGTNLFDQAFSESVIDSFDFDNPTKPEWYCIEGGTSLLVDAMKETLVHKVQ 247 Query: 250 KSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPK 309 + ++ + L+ V + +D S YS V + +LG L ++ Sbjct: 248 NNKRVEAISIDLDAP----DDGNMSVKIGGKDYSGYST--VFNTTALGCLDRMDLR-GLN 300 Query: 310 LPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEG----KGREFFLYASSRRGYYGVWQEFEK 365 L + AI TK+ LKF +W + G R Y + + Sbjct: 301 LHPTQADAIRCLHYDNSTKVALKFSYPWWIKDCGITCGGAASTDLPLRTCVYPSYNLGDT 360 Query: 366 QYPDANVLLVTVTDEESRRIEQQSDEQ-----TKAEIMQVLRKMFPGKDVPDATDILVPR 420 +A +L +++ RI + + E+++++ + T + Sbjct: 361 G--EAVLLASYTWSQDATRIGSLVKDAPPQPPKEDELVELILQNLARLHAEHMTYEKIKE 418 Query: 421 ----------WWSDRFYKGTFSNWPVGVNRYEYDQLRAPV--GRVYFTGEHTSEHYNGYV 468 W +D G F+ + G Y L P G+ + GE +S H+ ++ Sbjct: 419 AYTGVYHAYCWANDPNVGGAFALFGPGQFSNLYPYLMRPAAGGKFHIVGEASSVHH-AWI 477 Query: 469 HGAYLSGIDS 478 G+ S + Sbjct: 478 IGSLESAYTA 487 >3WE0-A nrPDB Length = 580 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 96/519 (18%), Positives = 171/519 (32%), Gaps = 57/519 (10%) Query: 14 ALLLALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMH 73 A L ++ A+HG V +VGAG++G+ AA L + G+ + + EA+ +GGR+ Sbjct: 54 AGLGSIPAARHGE-------EVAIVGAGIAGLVAAYELMKLGLKPV-VYEAS-KMGGRLR 104 Query: 74 KTNF---AGINVELGANWVEGVNGGKMNPIWPIVNST------LKLRNFRSDFDYLAQNV 124 F GI ELG + + + + T L + + D Q Sbjct: 105 SQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTY 164 Query: 125 YKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPAT 184 Y E Q+ + E G + A D+ L T Sbjct: 165 YAEKAADL-PALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRT 223 Query: 185 PVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVY--FVADQRGYEAVVYYLAG 242 D V F + V SDF + + F + + + G Sbjct: 224 FYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVG 283 Query: 243 QYLKTDDKSGKIVDPR------------LQLNKV---VREIKYSPGG---VTVKTEDNSV 284 + + V R L V+ I + G VT D Sbjct: 284 GVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRH 343 Query: 285 YSADYVMVSASLGVLQSDLIQFKPKLPTWKV-RAIYQFDMAVYTKIFLKFPRKFWPE--- 340 Y+A +++ L + I + L + K+ A+ + +K F+ R FW + Sbjct: 344 YAA---VLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDP 400 Query: 341 GKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQV 400 GR+ + R G + + L ++ ++ E+ + Sbjct: 401 ETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDA 460 Query: 401 LRKMFPGKDV--PDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRA------PVGR 452 L+K++P D+ D + W +D + G F G RY PV + Sbjct: 461 LKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQ 520 Query: 453 --VYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKK 489 ++ G+ S +V GA + +++ ++N K Sbjct: 521 RGIFIAGDDVSWT-PAWVEGAVQTSLNAVWGIMNHFGGK 558 >3LOV-A nrPDB Length = 475 Score = 89.2 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 79/490 (16%), Positives = 163/490 (33%), Gaps = 69/490 (14%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGIT-DLLILEATDHIGGRMHKTNFAGINVELGAN 87 R+++VG G++G++AA A ++ +LEA + +GG++ G +E G + Sbjct: 1 GMSSKRLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPD 60 Query: 88 WVEGVNGGKMNPIWPIV-NSTLKLRNFRSDFDYLAQNVYKEDGGVY-------------- 132 + I I L N F ++ G Sbjct: 61 SYVARKHILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLDLFRQTT 120 Query: 133 ------DEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNG-PATP 185 ++ + +DS+ + + L R + +++L E +G A Sbjct: 121 LLTEEEKQEVADLLLHPSDSLRIPEQDI--PLGEYLRPRLGDALVEKLIEPLLSGIYAGN 178 Query: 186 VDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYL 245 +D + + + A + SL + L D + + L Sbjct: 179 IDQMSTFATYPQFVANEQKAGSLFEGMRLMRPLDQLPQTPQTTIKATGQ--FLSLETGLE 236 Query: 246 KTDDKSGKIVD-PRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLI 304 ++ ++++ ++L + I G +KT+ Y ADYV+++ ++ Sbjct: 237 SLIERLEEVLERSEIRLETPLLAISREDGRYRLKTDHGPEY-ADYVLLTIP----HPQVV 291 Query: 305 QFKPK--LPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVW-- 360 Q P LP + Q + + F ++ +G + +RR Y + Sbjct: 292 QLLPDAHLPE-----LEQLTTHSTATVTMIFDQQQSLPIEG---TGFVVNRRAPYSITAC 343 Query: 361 ----QEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDI 416 Q++ PD VL V + + +SDE + ++Q L K+ + + Sbjct: 344 TAIDQKWNHSAPDHTVLRAFVGRPGNDHLVHESDEVLQQAVLQDLEKICGRT--LEPKQV 401 Query: 417 LVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNG-YVHGAYLSG 475 ++ R + VG R+ E Y G Y+ G G Sbjct: 402 IISR------LMDGLPAYTVGH-----------ADRIQRVREEVLAQYPGIYLAGLAYDG 444 Query: 476 IDSAEILINC 485 + + + + Sbjct: 445 VGLPDCVASA 454 >3I6D-A nrPDB Length = 470 Score = 81.8 bits (200), Expect = 6e-16, Method: Composition-based stats. Identities = 79/479 (16%), Positives = 155/479 (32%), Gaps = 63/479 (13%) Query: 35 VIVVGAGMSGISAA----KRLSEAGIT-DLLILEATDHIGGRMHKTNFAGINVELGANWV 89 V+++G G++G++AA K + E + +L ++EA+ +GG++ G +E G + Sbjct: 8 VVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKKDGYIIERGPDSF 67 Query: 90 EGVNGGKMNPIWPIVNSTLKLRNF-RSDFDYLAQNVYKEDGGVY----DEDYVQKRIELA 144 + + L + N + + + ++ G + L Sbjct: 68 LERKKSAPQLVKDLGLEHLLVNNATGQSYVLVNRTLHPMPKGAVMGIPTKIAPFVSTGLF 127 Query: 145 DSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPR 204 + + L AS D Q L E V + +A Sbjct: 128 SLSGKARAAMDFILPASKTKD-----DQSLGEFFRRRVGDEVVENLIEPLLSGIYAGDID 182 Query: 205 VTSLQNTVPLATFSDFGDDVYFVA-----DQRGYEAVVYYLAGQYLKTDDKSGKIVDP-- 257 SL +T P ++ + Q + + GQ+ +V+ Sbjct: 183 KLSLMSTFPQFYQTEQKHRSLILGMKKTRPQGSGQQLTAKKQGQFQTLSTGLQTLVEEIE 242 Query: 258 -RLQLNKV-----VREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLP 311 +L+L KV V ++ +S +++ ++ AD V+V+A L +LP Sbjct: 243 KQLKLTKVYKGTKVTKLSHSGSCYSLELDNGVTLDADSVIVTAPHKAAAGML----SELP 298 Query: 312 TWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQY---- 367 + + + L FP E + SR + + Sbjct: 299 A--ISHLKNMHSTSVANVALGFPEGSVQMEH--EGTGFVISRNSDFAITACTWTNKKWPH 354 Query: 368 --PDANVLLVTVTDE-ESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSD 424 P+ LL + I SD +++ L+K+ + V RW Sbjct: 355 AAPEGKTLLRAYVGKAGDESIVDLSDNDIINIVLEDLKKVMNING--EPEMTCVTRWHE- 411 Query: 425 RFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNG-YVHGAYLSGIDSAEIL 482 + + VG + +LR E + Y G Y+ GA G+ + + Sbjct: 412 -----SMPQYHVGHKQRI-KELR----------EALASAYPGVYMTGASFEGVGIPDCI 454 >5MOG-A nrPDB Length = 497 Score = 78.4 bits (191), Expect = 6e-15, Method: Composition-based stats. Identities = 85/477 (17%), Positives = 173/477 (36%), Gaps = 53/477 (11%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK-TNFAGINVELGANWVEGV 92 +V++ GAG++G+S AK L++AG ++LEA D +GG++ + G E G + G Sbjct: 19 QVVIAGAGLAGLSTAKYLADAG-HKPILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGA 77 Query: 93 NGGKMNPIWPI-VNSTLKLRNFR------------SDFDYLAQNVYKEDGGVYDEDYVQK 139 N + +N L+ + S FD+ + + G++ + + Sbjct: 78 YPNIQNLFGELGINDRLQWKEHSMIFAMPNKPGEFSRFDF-PETLPAPLNGIW---AILR 133 Query: 140 RIELA----DSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKF 195 E+ +G + + + + + Q D V Sbjct: 134 NNEMLTWPEKVKFALGLLPAMVGGQAYVEAQDGFTVSEWMKKQGVPD-RVNDEVFIAMSK 192 Query: 196 DYEFAEPPRVTSLQNTVPLATFSDF--GDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGK 253 F P ++ + L F G + F+ D E + + Sbjct: 193 ALNFINPDELSMQCILIALNRFLQEKHGSKMAFL-DGNPPERLCMPIVDHVRSL------ 245 Query: 254 IVDPRLQLNKVVREIKYSPGGVT--VKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLP 311 ++LN +++I+ +P G D + + D + + + +L+ + Q Sbjct: 246 --GGEVRLNSRIQKIELNPDGTVKHFALTDGTQITGDAYVFATPVDILKLLVPQ------ 297 Query: 312 TWKV----RAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQY 367 WK + + + + + F RK F +S Y + K+Y Sbjct: 298 EWKEISYFKKLEKLVGVPVINVHIWFDRKL-KNTYDHLLFSRSSLLSVYADMSVTC-KEY 355 Query: 368 PDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFY 427 D N ++ + + +SD + MQ L K+FP + D + + ++ + Sbjct: 356 YDPNRSMLELVFAPAEEWVGRSDTEIIEATMQELAKLFPDEIAADQSKAKILKYHVVKTP 415 Query: 428 KGTFSNWPVGVNRYEYDQL-RAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILI 483 + + P + L R+P+ Y G++T + Y + GA LSG A+ ++ Sbjct: 416 RSVYKTIP---DCEPCRPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQSVV 469 >1SEZ-A nrPDB Length = 504 Score = 67.2 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 80/510 (15%), Positives = 169/510 (33%), Gaps = 74/510 (14%) Query: 25 GSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 G + RV V+GAG+SG++AA +L G+ ++ + EA GG++ + G+ + Sbjct: 6 GEDKHSSAKRVAVIGAGVSGLAAAYKLKIHGL-NVTVFEAEGKAGGKLRSVSQDGLIWDE 64 Query: 85 GANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRI--E 142 GAN + G I + + + Y+A+N V I Sbjct: 65 GANTMTESEGDVTFLIDSLGLREKQQFPLSQNKRYIARNGTP----VLLPSNPIDLIKSN 120 Query: 143 LADSVEEMGEKLSAT-LHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAE 201 + ++ L +S Q + VD ++D + Sbjct: 121 FLSTGSKLQMLLEPILWKNKKLSQVSDSHESVSGFFQRHFGKEVVDYLIDPFV-AGTCGG 179 Query: 202 PPRVTSLQNTVPLATFSD---------------------FGDDVYFVADQRGYEAVVYYL 240 P S+ ++ P + A+++ +L Sbjct: 180 DPDSLSMHHSFPELWNLEKRFGSVILGAIRSKLSPKNEKKQGPPKTSANKKRQRGSFSFL 239 Query: 241 AGQYLKTDDKSGKIVDPRLQLNKVVREI------KYSPGGVTVKTEDNSVYSA-----DY 289 G TD + + L+LN V E+ + ++ + + D Sbjct: 240 GGMQTLTDAICKDLREDELRLNSRVLELSCSCTEDSAIDSWSIISASPHKRQSEEESFDA 299 Query: 290 VMVSASLGVLQSDLI--QFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRK--------FWP 339 V+++A L ++S I + P L I + D + + F R+ F Sbjct: 300 VIMTAPLCDVKSMKIAKRGNPFLL----NFIPEVDYVPLSVVITTFKRENVKYPLEGFGV 355 Query: 340 EGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQ 399 +E + + ++ + + V +R + + S + K + Sbjct: 356 LVPSKEQQHGLKTLGTLFSSMMFPDRAPNNVYLYTTFVGGSRNRELAKASRTELKEIVTS 415 Query: 400 VLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEY-----DQLRAPVGRVY 454 L+++ + P + L W +P+ + Y+ D++ + ++ Sbjct: 416 DLKQLLGAEGEPTYVNHLY--WSK---------AFPLYGHNYDSVLDAIDKMEKNLPGLF 464 Query: 455 FTGEHTSEHYNGYVHGAYLSGIDSAEILIN 484 + G H G A SG ++A+++I+ Sbjct: 465 YAGNHRGGLSVG---KALSSGCNAADLVIS 491 >4IVM-B nrPDB Length = 483 Score = 59.9 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 66/434 (15%), Positives = 134/434 (30%), Gaps = 48/434 (11%) Query: 35 VIVVGAGMSGISAAKRLSEAGI-TDLLILEATDHIGGRMHKTNFA-GINVELGANWVEGV 92 V+V+G G+SG++A+ LS A ++++E+++ +GG + G ELG + Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPGGIRPA 70 Query: 93 NGGKMNPIWPIVNSTLKLRNFRSDFDY-LAQNVYKEDGG-------------VYDEDY-- 136 + + L D+ AQN + GG + Sbjct: 71 GALGARTLLLVSELGLDSEVLPVRGDHPAAQNRFLYVGGALHALPTGLRGLLRPSPPFSK 130 Query: 137 VQKRIELADSVEEMGEKLSATLHASGRD----DMSILAMQRLNEHQPNGPATPVDMVVDY 192 L + + G++ T+H+ + +++ LAM L G + + + Sbjct: 131 PLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVASLAMDSLCRGVFAGNSRELSI---R 187 Query: 193 YKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSG 252 F F S+ + L D + + L G Sbjct: 188 SCFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQALAERWSQWSLRGGLEMLPQALE 247 Query: 253 KIVDPR---LQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPK 309 + R + + V + G + +S AD+V+ + VL L Sbjct: 248 THLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPASVLSELLPAEAAP 307 Query: 310 LPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYG--------VWQ 361 L RA+ + L++ P + F + G V Sbjct: 308 L----ARALSAITAVSVAVVNLQYQGAHLP----VQGFGHLVPSSEDPGVLGIVYDSVAF 359 Query: 362 EFEKQYPDANVLLVTVTDEESRRIEQ----QSDEQTKAEIMQVLRKMFPGKDVPDATDIL 417 + P + V + + +E S E + + K++P + Sbjct: 360 PEQDGSPPGLRVTVMLGGSWLQTLEASGCVLSQELFQQRAQEAAATQLGLKEMPSHCLVH 419 Query: 418 VPRWWSDRFYKGTF 431 + + ++ G + Sbjct: 420 LHKNCIPQYTLGHW 433 >4DGK-A nrPDB Length = 501 Score = 55.3 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 37 VVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGK 96 V+GAG G++ A RL AGI +L+LE D GGR + G + G + Sbjct: 6 VIGAGFGGLALAIRLQAAGIP-VLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITD--PSA 62 Query: 97 MNPIWPIVNSTLK 109 + ++ + LK Sbjct: 63 IEELFALAGKQLK 75 >4YRY-B nrPDB Length = 468 Score = 51.8 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 51/282 (18%), Positives = 100/282 (35%), Gaps = 41/282 (14%) Query: 26 SLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG----RMHKTNFAGIN 81 LA + +V VVG+G +G++AA L++ G + I EA GG + + Sbjct: 134 PLAGSKKEKVAVVGSGPAGLTAAADLAKMGYH-VDIFEAFHKPGGVLVYGIPEFRLPKRI 192 Query: 82 VELGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYL----AQNVYKEDG-------G 130 VE +++ + + +V T+K++ S++D + K G G Sbjct: 193 VEREVSYIRKLGVNFH--LNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNG 250 Query: 131 VYDEDYVQKRIEL--------ADSVEEMGEKL-----SATLHASGRDDMSILAMQRLNEH 177 VY + R+ L D+ +G+K+ T + R + + A + + Sbjct: 251 VYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVY 310 Query: 178 QPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVV 237 + P + +Y A + L T+P+ D +V + R Sbjct: 311 RRTEREMP------ARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEA 364 Query: 238 YYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKT 279 + S +++ + V+ I P V + Sbjct: 365 DGSGRPRPVPIEGSNFVLEVDM----VIEAIGQGPNRVLLSE 402 >5NMX-A nrPDB Length = 425 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 47/121 (38%), Gaps = 14/121 (11%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 RV V+GAG SG++AA+ L +AG ++++ E H+GG E G Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGF-EVMVFERYHHVGG-TWNYTDETWMSEDG-------- 52 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEK 153 P++ + L + + + + +G V K + ++ + Sbjct: 53 ----RPVYSSMYQNLFVNLPKELMAFPDFPFHDIEGSYVPSKEVLKYFDNFTDAFDLRKL 108 Query: 154 L 154 + Sbjct: 109 I 109 >5ZBC-A nrPDB Length = 451 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 70/477 (14%), Positives = 155/477 (32%), Gaps = 82/477 (17%) Query: 35 VIVVGAGMSGISAAKRLSEA----GITDLLILEATDHIGGRMHKTNFAG-INVELGANWV 89 + +VGAG+SG++ A L ++ G++ L I + GGR+ G ++ELGA Sbjct: 27 ICIVGAGISGLTCASHLLDSPACRGLS-LRIFDMQQEAGGRIRSKMLDGKASIELGA--- 82 Query: 90 EGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEE 149 G + P S ++ Y + VY ++ + + ++ Sbjct: 83 ----GRYSPQLHPHFQSAMQ--------------HYSQKSEVYPFTQLKFKSHVQQKLKR 124 Query: 150 MGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQ 209 +LS L G++ + G + V M+ +D F Sbjct: 125 AMNELSPRLKEHGKESFLQFVSRY------QGHDSAVGMIRS-MGYDALFLPDISAEMAY 177 Query: 210 NTV----PLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVV 265 + V + + +D + +F A + G+ ++ + + K R L + Sbjct: 178 DIVGKHPEIQSVTDNDANQWF-AAETGFAGLIQGIKAKV--------KAAGARFSLGYRL 228 Query: 266 REIKYSPGGVTVKTEDNSVYS----ADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQF 321 ++ G ++ + + +++++ + + F P+ W Sbjct: 229 LSVRTDGDGYLLQLAGDDGWKLEHRTRHLILAIPPSAMAGLNVDF-PE--AWSGARYGSL 285 Query: 322 DMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEE 381 K FL + +W + K V K Y + L TD E Sbjct: 286 P---LFKGFLTYGEPWWLDYK---------LDDQVLIVDNPLRKIYFKGDKYLFFYTDSE 333 Query: 382 SRRIEQ----QSDEQTKAEIMQVLRKMFP--GKDVPDATDILVPRWWSD-RFYKGTFSNW 434 + + ++ +I L + +P + W F + + + Sbjct: 334 MANYWRGCVAEGEDGYLEQIRTHLASALGIVRERIPQPLAHVHKYWAHGVEFCRDSDIDH 393 Query: 435 PVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMC 491 P ++ + + + G++ G LS +++ +L+ K+ Sbjct: 394 PSALSHRDSGII---------ACSDAYTEHAGWMEGGLLSAREASRLLLQRIAAKLA 441 >2IVE-A nrPDB Length = 478 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 27 LAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA 86 + T G V VVG G+SG++ A L G TD ++LE++ +GG + AG VE G Sbjct: 11 MPRTTGMNVAVVGGGISGLAVAHHLRSRG-TDAVLLESSARLGGAVGTHALAGYLVEQGP 69 Query: 87 N 87 N Sbjct: 70 N 70 >1I8T-A nrPDB Length = 367 Score = 49.9 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 42/247 (17%), Positives = 76/247 (30%), Gaps = 30/247 (12%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGG 95 I+VG+G+ G A L + +L++E +HIGG + + GI + + N Sbjct: 5 IIVGSGLFGAVCANELKKLN-KKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTND- 62 Query: 96 KMNPIWPIVNSTLKLRNF--RSDFDYLAQ--------NVYKEDGGVYDEDYVQKRIELAD 145 IW VN ++ F Y + N + + GV D Q I Sbjct: 63 --KYIWDYVNDLVEFNRFTNSPLAIYKDKLFNLPFNMNTFHQMWGVKDPQEAQNIINAQK 120 Query: 146 SVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRV 205 ++ G+K+ L + Q L + + P Sbjct: 121 --KKYGDKVPENLEEQAISLVGEDLYQALIKGYTEK-----QWGRSAKEL-------PAF 166 Query: 206 TSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVV 265 + V +++ D Y GY ++ + + + L Sbjct: 167 IIKRIPVRFTFDNNYFSDRYQGIPVGGYTKLIEKMLEGVD--VKLGIDFLKDKDSLASKA 224 Query: 266 REIKYSP 272 I Y+ Sbjct: 225 HRIIYTG 231 >4MO2-B nrPDB Length = 368 Score = 48.3 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 36/214 (16%), Positives = 75/214 (35%), Gaps = 25/214 (11%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGG 95 ++VG+G+ G A +E G T L++E +HIGG + N INV + + Sbjct: 5 LIVGSGLFGSIFAYEATEKGYT-CLVVEQREHIGGNCYTENIKNINVHKYGAHIFRTSDQ 63 Query: 96 KMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLS 155 IW + F ++ + +Y ++ + + G + Sbjct: 64 N---IWDY------MNQFCEFNHFINSPI-----AIYKDEIYNLPFNMNTFSKLWG--IK 107 Query: 156 ATLHASGRDDMSILAMQRLNEHQPNGPATPV------DMVVDYYKFDYEFAEPPRVTSLQ 209 A +M +Q ++ + V ++ Y + + + S+ Sbjct: 108 TPNEARKIIEMQKQIIQHPPKNLEEQAISLVGTDVYEKLIKGYTEKQWGRSCKDLPASII 167 Query: 210 NTVPLATFSD--FGDDVYFVADQRGYEAVVYYLA 241 +P+ D + +D Y + GY A+ + Sbjct: 168 RRLPVRYIYDNNYFNDPYQGIPKGGYTAIFDKML 201 >3K30-A nrPDB Length = 690 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 1/45 (2%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM 72 A RV+VVGAG SG+ AA+ L G D+++ EA +GGR+ Sbjct: 387 AKESDARVLVVGAGPSGLEAARALGVRGY-DVVLAEAGRDLGGRV 430 >4ZCC-A nrPDB Length = 336 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVE 90 + ++G G++G+SAA+ L+ AG + + + + GGRM ++++GA + Sbjct: 5 IAIIGTGIAGLSAAQALTSAG-HQVHLFDKSRGSGGRMSSKRSDAGSLDMGAQYFT 59 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 45/124 (36%), Gaps = 17/124 (13%) Query: 360 WQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGK---DVPDATDI 416 W + P + L + + + +Q+ + ++ ++++ L F +P Sbjct: 212 WLARNRSKPGRDDTLDSWVLHATSQWSRQNLDASREQVIEHLHGAFAELIDCAMPAPVFS 271 Query: 417 LVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGI 476 L RW + A +G +Y G+ +G V GA+LSG Sbjct: 272 LAHRWL----------YARPAGSHEWGALSDADLG-IYVCGDWC---LSGRVEGAWLSGQ 317 Query: 477 DSAE 480 ++A Sbjct: 318 EAAR 321 >3KKJ-A nrPDB Length = 336 Score = 46.0 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVE 90 + ++G G++G+SAA+ L+ AG + + + + GGRM +++GA + Sbjct: 5 IAIIGTGIAGLSAAQALTAAG-HQVHLFDKSRGSGGRMSSKRSDAGALDMGAQYFT 59 Score = 32.9 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 33/231 (14%), Positives = 74/231 (32%), Gaps = 34/231 (14%) Query: 256 DPRLQLNKVVREIKYSPGGVTV---KTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPT 312 D + + + E+ + + +++ +S +V+++ + L Sbjct: 119 DMPVSFSCRITEVFRGEEHWNLLDAEGQNHGPFS--HVIIATPAPQASTLL-----AAAP 171 Query: 313 WKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANV 372 + M + L F +G F + W + P+ + Sbjct: 172 KLASVVAGVKMDPTWAVALAFETPLQTPMQGC-FVQDSPLD------WLARNRSKPERDD 224 Query: 373 LLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGK---DVPDATDILVPRWWSDRFYKG 429 L T + + +Q+ + ++ ++++ L F +P L RW Sbjct: 225 TLDTWILHATSQWSRQNLDASREQVIEHLHGAFAELIDCTMPAPVFSLAHRWL------- 277 Query: 430 TFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAE 480 A +G +Y G+ +G V GA+LSG ++A Sbjct: 278 ---YARPAGAHEWGALSDADLG-IYVCGDWC---LSGRVEGAWLSGQEAAR 321 >2UZZ-A nrPDB Length = 372 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 18/149 (12%) Query: 261 LNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQ 320 N V I++ GVT++T D Y A +V A G DL+ P P KV A YQ Sbjct: 168 FNCPVTAIRHDDDGVTIETADGE-YQAKKAIVCA--GTWVKDLLPELPVQPVRKVFAWYQ 224 Query: 321 FDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQY-PDANVLLVTVTD 379 D K K F + YYG E + N V Sbjct: 225 ADGRYSVK------------NKFPAFTGELPNGDQYYGFPAENDALKIGKHNG--GQVIH 270 Query: 380 EESRRIEQQSDEQTKAEIMQVLRKMFPGK 408 R+ +E LR + PG Sbjct: 271 SADERVPFAEVVSDGSEAFPFLRNVLPGI 299 >3KYB-A nrPDB Length = 390 Score = 44.9 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 42/245 (17%), Positives = 81/245 (33%), Gaps = 23/245 (9%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL---GANW 88 ++++VGAG SG ++L+E G + I++ DHIGG + + NV + G + Sbjct: 3 SKKILIVGAGFSGAVIGRQLAEKG-HQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHI 61 Query: 89 VEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVE 148 N N I + ++ + ++ + + + S + Sbjct: 62 FHTDNETVWNYINKHAEMMPYVNRVKATVNGQVFSLP------INLHTINQFFSKTCSPD 115 Query: 149 EMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSL 208 E ++ ++ D Q L Y + S+ Sbjct: 116 EARALIAEKGDSTIADP-QTFEEQALRFIGKELYEAFF---KGYTIKQWGMQPSELPASI 171 Query: 209 QNTVPLATFSDFGDDVYFVA-----DQRGYEAVVYYLAGQY-LKTDDKSGKIVDPRLQLN 262 +P+ DD YF + GY ++ + +K D + IVD R + Sbjct: 172 LKRLPVRF---NYDDNYFNHKFQGMPKCGYTQMIKSILNHENIKVDLQREFIVDERTHYD 228 Query: 263 KVVRE 267 V Sbjct: 229 HVFYS 233 >2CVJ-A nrPDB Length = 180 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 19/52 (36%), Positives = 27/52 (51%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA 86 VIVVG G SG+SAA L+ AG+ L++ + G N+ G+ E Sbjct: 4 VIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGLLDEPSG 55 >4P9S-A nrPDB Length = 848 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 60/178 (33%), Gaps = 11/178 (6%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGG 95 +++G G G+S A L++AG+ D+++LE ++ G G N ++ ++ Sbjct: 27 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGIN-LKKIHYD 85 Query: 96 KMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLS 155 + + T ++ F DE Q + E+ + Sbjct: 86 SIKLYERLEEETGQVVGFHQPGSIRLATTP----ERVDEFKYQMTRTNWHATEQYIIEPE 141 Query: 156 ATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVD----YYKFDYEFAEPPRVTSLQ 209 +M + N +G P + + K+ P VTSL+ Sbjct: 142 KIHELFPLLNMDKILAGLYN--PGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLK 197 >5JFC-L nrPDB Length = 474 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 8/50 (16%) Query: 21 LAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 + ++G +V ++GAG +G++ A L++ G ++ I EA GG Sbjct: 150 IKRNGK-------KVAIIGAGPAGLTCAADLAKMGY-EVTIYEALHQPGG 191 >5VJ7-A nrPDB Length = 476 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 8/50 (16%) Query: 21 LAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 + ++G +V ++GAG +G++ A L++ G ++ I EA GG Sbjct: 150 IKRNGK-------KVAIIGAGPAGLTCAADLAKMGY-EVTIYEALHQPGG 191 >5L46-A nrPDB Length = 841 Score = 42.2 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 24/38 (63%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMH 73 +++G G G+S A L++AG+ D+++LE ++ G Sbjct: 26 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 63 >3UP5-A nrPDB Length = 545 Score = 41.8 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVE 83 A + +V+GAG++GI A +++AG+ +L +EA + +GG + + G ++ Sbjct: 5 AKSPALDAVVIGAGVTGIYQAFLINQAGMK-VLGIEAGEDVGGTWYWNRYPGCRLD 59 >4REP-A nrPDB Length = 495 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 41/280 (14%), Positives = 87/280 (31%), Gaps = 20/280 (7%) Query: 50 RLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGKMNPIWPIVNS--T 107 RL G + + I E D+ GG++H G +LG + + N Sbjct: 19 RLRHQGYS-VTIFEKNDYAGGKLHAIEKDGYRFDLGPSLFT-LPHLVENLFALFPEEIID 76 Query: 108 LKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMS 167 ++ F Y + +++ ++ + +K A + S Sbjct: 77 FGYKSKAISFHYFWDDGTLFKASTDSSQFIEDASKVFKEEKSTIKKYLAKSKSKYELTKS 136 Query: 168 ILAMQRLNEHQPNGPATPVDMVV---------DYYKFDYEFAEPPRVTSL-QNTVPLATF 217 + + L++ V +V + +F P + + Sbjct: 137 LFLEKSLHKATTYFSLDTVKAIVHAPFLGLNNTLNDENSKFKNPKLTQLFNRYATYNGSS 196 Query: 218 SDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKI---VDPRLQLNKVVREIKYSPGG 274 + + YY G + ++ V + + + V I S Sbjct: 197 PYQTPGIMTMIPHLELGLGTYYPDGGMHRISQSLFELAQKVGVKFRFRESVTNITTSKNK 256 Query: 275 VT-VKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTW 313 VT V+T++ S Y +D V+ + + +L++ P P Sbjct: 257 VTGVETKNGS-YLSDLVVSNMDIVPTYRNLMKDVPA-PEK 294 >3UKH-A nrPDB Length = 519 Score = 41.8 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 71/491 (14%), Positives = 148/491 (30%), Gaps = 66/491 (13%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK-TNFAGINVELGANWVEGVN 93 V+V+GAG +G+ AAKRL++ +I+++ + GG G ++G + + Sbjct: 9 VLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVTPEGFLYDVGGHVIFSH- 67 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNV-YKEDGGVYDEDYVQKRIELA---DSVEE 149 + + L + D Y Q + Y G + Q I + + V+ Sbjct: 68 -------YKYFDDCLDEALPKEDDWYTHQRISYVRCQGQWVPYPFQNNISMLPKEEQVKC 120 Query: 150 MGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFD-----YEFAEPPR 204 + + A L A + + + G A ++ + + A Sbjct: 121 IDGMIDAALEARVANTKPKTFDEWIVRMMGTGIADLFMRPYNFKVWAVPTTKMQCAWLGE 180 Query: 205 VTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKV 264 + N + T G + G + R Sbjct: 181 RVAAPNLKAVTTNVILGKTAGNWGPNATFRFPARGGTGGIWIAVANTLPKEKTRFGEKGK 240 Query: 265 VREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVL-----QSDLIQFKPKLPTWKVRAI- 318 V ++ + TV +D + ++ + ++ L +L+ +L I Sbjct: 241 VTKV--NANNKTVTLQDGTTIGYKKLVSTMAVDFLAEAMNDQELVGLTKQLFYSSTHVIG 298 Query: 319 ----YQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYY----GVWQEFEKQYP-- 368 + K +L FP P + F Y+ + Q + P Sbjct: 299 VGVRGSRPERIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPEASKKLPTMQLADGSRPQS 358 Query: 369 ----DANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRK---MFPGKDVPD--------- 412 + + + ES ++ + E A+ +Q L + P ++ Sbjct: 359 TEAKEGPYWSIMLEVSES-SMKPVNQETILADCIQGLVNTEMLKPTDEIVSTYHRRFDHG 417 Query: 413 -ATDILVPRWWS----------DRFYKGTFSNWPVGVNRYEYDQL--RAPVGRVYFTGEH 459 T L D + +G F +W V ++ + V + Sbjct: 418 YPTPTLEREGALTQILPKLQDKDIWSRGRFGSWRYEVGNQDHSFMLGVEAVDNIVNGAVE 477 Query: 460 TSEHYNGYVHG 470 + +Y +V+G Sbjct: 478 LTLNYPDFVNG 488 >5BR7-A nrPDB Length = 393 Score = 41.4 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 68/210 (32%), Gaps = 28/210 (13%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 +IVVG+G+ G++ A+R + +LI+E H+GG + +E+ + + Sbjct: 6 LIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEI-HKYGAHLFH 64 Query: 95 GKMNPIWPIVNSTLKLRNFRSD-----------FDYLAQNVYKEDGGVYDEDYVQKRIEL 143 +W VN ++ F + + G Y D ++ I+ Sbjct: 65 TSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKE 124 Query: 144 ------ADSVEEMGEK----LSAT-LHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDY 192 + + EK + A RD ++ PA + + Sbjct: 125 QSAEIDSKDATNLEEKAISLIGRPLYEAFIRD----YTAKQWQTDPKELPAGNITRLPVR 180 Query: 193 YKFDYEFAEPPRVTSLQNTVPLATFSDFGD 222 Y FD + L S+ D Sbjct: 181 YNFDNRY-FNDTYEGLPVDGYAQWLSNMAD 209 >4RPJ-A nrPDB Length = 399 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 1/81 (1%) Query: 37 VVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGK 96 VVG+G G++ A+R++ +L+LE HIGG + +E+ + + Sbjct: 12 VVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEV-HKYGAHLFHTS 70 Query: 97 MNPIWPIVNSTLKLRNFRSDF 117 +W V ++R Sbjct: 71 NKRVWDYVRQFTDFTDYRHRV 91 >4OVI-A nrPDB Length = 542 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 V+VVGAG SG+ A RL E G + + ++E +GG + + G ++ Sbjct: 19 VLVVGAGFSGLYALYRLRELGRS-VHVIETAGDVGGVWYWNRYPGARCDI 67 >1RP0-A nrPDB Length = 284 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMH 73 V+VVGAG +G+SAA +S+ + I+E + GG Sbjct: 42 VVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW 80 >4AP1-A nrPDB Length = 549 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 T V+VVGAG++G+ A R G+T + EA +GG + + G ++ Sbjct: 18 GTTSYDVVVVGAGIAGLYAIHRFRSQGLT-VRAFEAASGVGGVWYWNRYPGARCDV 72 >3LXD-A nrPDB Length = 415 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM 72 +V+G G G+ AA L++ G+ ++ +LEA + R+ Sbjct: 155 AVVIGGGYIGLEAAAVLTKFGV-NVTLLEALPRVLARV 191 >2RGJ-A nrPDB Length = 402 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 23/34 (67%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHI 68 +++ GAG+ G+S A L +AGI + +LE++ I Sbjct: 7 ILIAGAGIGGLSCALALHQAGIGKVTLLESSSEI 40 >4YNU-A nrPDB Length = 571 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 27/58 (46%) Query: 30 TVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGAN 87 T IVVG G SG+ A RLSE +L+LEA + TN G + G+ Sbjct: 3 TTTYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAGASVFNNPDVTNANGYGLAFGSA 60 >3ZZN-A nrPDB Length = 310 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 97/298 (32%), Gaps = 14/298 (4%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWV-EGV 92 +V +VG+GM G + A L+ G+ ++L D + H + WV G Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWAGS 61 Query: 93 NGGKMNPIWPIVNSTLKLRNFRSDFDYLAQN------VYKEDGGVYDEDYVQKRIELADS 146 G ++ + + R + L +N V E + D Sbjct: 62 YGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDV 121 Query: 147 VEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVT 206 + ++ LS +IL R V Y ++ +E + Sbjct: 122 MTQVAYALSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGDSEVLVWS 181 Query: 207 SLQ-NTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVV 265 S Q VPL F++ D+ + V A + ++ + + L ++V Sbjct: 182 SAQVGGVPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGKGATYYGIGAG--LARLV 239 Query: 266 REIKYSPGGV-TVKTEDNSVYSADYVMVSASLGVLQSDLIQFK--PKLPTWKVRAIYQ 320 R I GV TV V V +S +L + + P L + A+ + Sbjct: 240 RAILTDEKGVYTVSAFTPEVAGVLEVSLSLP-RILGAGGVAGTVYPSLSPEERAALRR 296 >2GV8-A nrPDB Length = 447 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 34 RVIVVGAGMSGISAAK-RLSEAGITDLLILEATDHIGGRMHKTN 76 ++ ++GAG SG+ AK L+E + + E GG + Sbjct: 8 KIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGG-VWNYT 50 >1DOD-A nrPDB Length = 394 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 61/165 (36%), Gaps = 19/165 (11%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEAT--DHIGGRMHKTNFAGINVELGANWVEG 91 +V ++GAG SG+ + L +AGI ++ ILE D++ GR+ V+L + Sbjct: 4 QVAIIGAGPSGLLLGQLLHKAGIDNV-ILERQTPDYVLGRIRAGVLEQGMVDL----LRE 58 Query: 92 VNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMG 151 + +V+ +++ + + GG Y Q E+ Sbjct: 59 AGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRL---SGGKTVTVYGQ---------TEVT 106 Query: 152 EKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFD 196 L A G + A RL++ Q P + + + D Sbjct: 107 RDLMEAREACGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLD 151 >3RP7-A nrPDB Length = 407 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 6/86 (6%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIG--GRMHKTNFAGIN--VELG-ANW 88 + IV+GAG+ G+SAA L ++GI D + EA I G G+ LG + Sbjct: 25 KAIVIGAGIGGLSAAVALKQSGI-DCDVYEAVKEIKPVGAAISVWPNGVKCMAHLGMGDI 83 Query: 89 VEGVNGGKMNPIWPIVNSTLKLRNFR 114 +E G + S + F Sbjct: 84 METFGGPLRRMAYRDFRSGENMTQFS 109 >2YR5-A nrPDB Length = 721 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 41/214 (19%), Positives = 65/214 (30%), Gaps = 43/214 (20%) Query: 308 PKLPTWKVRAIYQFDMAVYTKIFLKFPRKF----WPEGKGREFFLYASSRRGYYGVW--- 360 P V AI Q MA +K+F W E S G + Sbjct: 458 PAANARIVTAIGQLHMARSSKVFATVKTAALDQPWVPQWRGEPIKAVVSDSGLAASYVVP 517 Query: 361 --QEFEKQYPDANVLLVTVTDEESRR-------IEQQSDEQTKAEIMQVLRKMFPG--KD 409 + Q P+ + LL + T E+ + Q+ + R M + Sbjct: 518 SPIVEDGQAPEYSSLLASYTWEDDSTRLRHDFGLYPQNPATETGTADGMYRTMVNRAYRY 577 Query: 410 VPDATDILVPRWW----------SDRFYKGTFSNWPVGVN---------------RYEYD 444 V A WW +DRF +N G RY Sbjct: 578 VKYAGASNAQPWWFYQLLAEARTADRFVFDWTTNKTAGGFKLDMTGDHHQSNLCFRYHTH 637 Query: 445 QLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDS 478 L A + +F + H G++ GA++S +++ Sbjct: 638 ALAASLDNRFFIASDSYSHLGGWLEGAFMSALNA 671 >4Y4M-A nrPDB Length = 290 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 22/29 (75%), Gaps = 1/29 (3%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILE 63 V++VGAG SG++ A+ L++ G +++LE Sbjct: 62 VVIVGAGPSGLTCARYLAKEGFK-VVVLE 89 >6BPY-A nrPDB Length = 374 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 7/66 (10%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLL---ILEATDHIGGRMHKT----NFAGIN 81 V +V+++G+G + +AA LS A + +L +L GG++ T NF G Sbjct: 1 GMVHTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFP 60 Query: 82 VELGAN 87 +G Sbjct: 61 DGIGGA 66 >2LDB-A nrPDB Length = 317 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 45/108 (41%), Gaps = 10/108 (9%) Query: 27 LAATVGPRVIVVGAGMSGISAAKRLSEAGITD-LLILEATDH--IGGRM---HKTNFAGI 80 + G RV+V+GAG G S L GI D +++++A + IG M H FA Sbjct: 1 MKNNGGARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPK 60 Query: 81 NVELGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKED 128 V++ W + + + I + + + D + +N+ Sbjct: 61 PVDI---WHGDYDDCRDADLVVIC-AGANQKPGETRLDLVDKNIAIFR 104 >5W4C-A nrPDB Length = 371 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 46/112 (41%), Gaps = 7/112 (6%) Query: 20 SLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLL---ILEATDHIGGRMHKTN 76 + G ++ + +V+++G+G G +AA L+ A + +L +L GG++ T Sbjct: 18 EPKRTGEVSKKMHSKVVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLTTTT 77 Query: 77 FAGINVELGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKED 128 +VE + EGV G +M + + + + +V Sbjct: 78 ----DVENFPGFPEGVTGTEMMDKFRAQSERFGTKIITETVARVDLSVRPFK 125 >3IP1-A nrPDB Length = 404 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 21 LAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATD 66 + + G + G V+++G G G++A L AG + +++ E ++ Sbjct: 205 IVRGGGIR--PGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSE 248 >5XGV-A nrPDB Length = 462 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 26/60 (43%) Query: 243 QYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSD 302 Q + ++ + + R++ + + ++ +P GV V T D V Y++ L + Sbjct: 98 QVERRLEERARSLGVRVRRSTEITSVRQTPDGVQVTTGDGEVVEGAYLVGCDGSASLVRE 157 >3FPZ-A nrPDB Length = 326 Score = 37.2 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGIT-DLLILEATDHIGGRMH 73 VI+VGAG SG+SAA +++ + I+E++ GG Sbjct: 68 VIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSW 107 >5EQD-A nrPDB Length = 400 Score = 37.2 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW 88 +T + VVG+G G++ A+R + +L++E HIGG + +E+ + Sbjct: 1 STGNFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYSEPEPETGIEV-HKY 59 Query: 89 VEGVNGGKMNPIWPIVNS 106 + +W V Sbjct: 60 GAHLFHTSNKRVWDYVRQ 77 >1NAA-A nrPDB Length = 541 Score = 37.2 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 18/28 (64%), Positives = 21/28 (75%), Gaps = 1/28 (3%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILE 63 I+VGAG GI AA RLSEAG +L+LE Sbjct: 6 IIVGAGPGGIIAADRLSEAG-KKVLLLE 32 >3DIN-A nrPDB Length = 871 Score = 36.8 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 51/154 (33%), Gaps = 7/154 (4%) Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADS-VEEMGE 152 G ++ ++ ++N+ L F+ D DY+ N G V D R+ + + Sbjct: 326 PGNVSLLYHLINALKALHLFKKDVDYVVMN-----GEVIIVDEFTGRLLPGRRYSGGLHQ 380 Query: 153 KLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTV 212 + A +++ A + M + EF + + + Sbjct: 381 AIEAKEGVPIKEESITYATITFQNYFRMYE-KLAGMTGTAKTEESEFVQVYGMEVVVIPT 439 Query: 213 PLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLK 246 DD+ F + YE +V + +Y K Sbjct: 440 HKPMIRKDHDDLVFRTQKEKYEKIVEEIEKRYKK 473 >3MJ4-A nrPDB Length = 397 Score = 36.8 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 30/74 (40%), Gaps = 7/74 (9%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGG 95 ++VGAG +G A+RL+ +G +LI++ HIGG + + + Sbjct: 33 LIVGAGFAGSVLAERLASSG-QRVLIVDRRPHIGGNAYDC------YDDAGVLIHPYGPH 85 Query: 96 KMNPIWPIVNSTLK 109 + V L Sbjct: 86 IFHTNSKDVFEYLS 99 >3ATQ-A nrPDB Length = 453 Score = 36.8 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 18/122 (14%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEAT--DHIGGR-----MHKTNFA--GINVELG 85 V+++G G +G SAA +LS G+ +L++++ + IG + + K +F G+ G Sbjct: 9 VLIIGGGFAGSSAAYQLSRRGLK-ILLVDSKPWNRIGDKPCGDAVSKAHFDKLGMPYPKG 67 Query: 86 ANWVEGVNGGK-----MNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDG-GVYDEDYVQK 139 +NG K M +W + +L ++ ++ G ++D K Sbjct: 68 EELENKINGIKLYSPDMQTVWTVNGEGFELN--APLYNQRVLKEAQDRGVEIWDLTTAMK 125 Query: 140 RI 141 I Sbjct: 126 PI 127 >4H7U-A nrPDB Length = 602 Score = 36.4 bits (82), Expect = 0.028, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 9/63 (14%) Query: 9 LLAVAALLLALSLAQHG-------SLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLI 61 LL++A LL + +A+ L + V IV G G +G+ A RLSE +L+ Sbjct: 12 LLSLA--LLGIQIARGAITYQHPDDLPSGVDYDFIVAGGGTAGLVVASRLSENSNWKVLV 69 Query: 62 LEA 64 +EA Sbjct: 70 IEA 72 >2TMD-A nrPDB Length = 729 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 29/107 (27%), Positives = 41/107 (38%), Gaps = 10/107 (9%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEG--V 92 V++VGAG SG AA+ L E+G T + + + + IGG H A + LG Sbjct: 392 VLIVGAGPSGSEAARVLMESGYT-VHLTDTAEKIGG--HLNQVAALP-GLGEWSYHRDYR 447 Query: 93 NGGKMNPIWPIVNSTLKLRNFRSDFD----YLAQNVYKEDGGVYDED 135 + S L L D Y A V G ++ D Sbjct: 448 ETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIATGARWNTD 494 >4C5O-A nrPDB Length = 357 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 1/36 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 V+V+G G SG+SA L +G++ + IL+A GG Sbjct: 6 VVVIGGGQSGLSAGYFLRRSGLSYV-ILDAEASPGG 40 >3JSK-A nrPDB Length = 344 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 1/50 (2%) Query: 25 GSLAATVGPRVIVVGAGMSGISAAKRLSEAGIT-DLLILEATDHIGGRMH 73 L A +++VGAG G+SAA LS + I+EA GG Sbjct: 72 ADLDAHAETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW 121 >2GAG-B nrPDB Length = 405 Score = 36.0 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%) Query: 27 LAATVGPR----VIVVGAGMSGISAAKRLSEA-GITDLLILEATDHIGGRMHKTN 76 L A P+ I+VG G G++ A L++ GIT++ +LE GG M + Sbjct: 12 LWANPEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNT 66 >4Y4N-A nrPDB Length = 286 Score = 36.0 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 21/29 (72%), Gaps = 1/29 (3%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILE 63 V +VG G SG++AA+ +++ G +++LE Sbjct: 55 VAIVGGGPSGLTAARYIAKEGYK-VVVLE 82 >6DLL-A nrPDB Length = 398 Score = 36.0 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 30/52 (57%), Gaps = 1/52 (1%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLI-LEATDHIGGRMHKTNFAGINVEL 84 +V ++GAG SG+ + L +AGI ++++ + +++ GR+ V+L Sbjct: 7 QVAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQGTVDL 58 >4UIR-A nrPDB Length = 646 Score = 36.0 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 38/286 (13%), Positives = 95/286 (33%), Gaps = 40/286 (13%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAG---ITDLLILEATDHIGGRMHKTNF--AGINVELG- 85 ++ ++G+G++G+SAA G ++ LE GG + G + G Sbjct: 62 NSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSLDGAGNPTDGYIIRGGR 121 Query: 86 --ANWVEGVNGGKMNPIWPIVNSTLK-LRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIE 142 E + + + + L +R D + Y + + ++ ++ + Sbjct: 122 EMDMTYENLWDMFQDIPALEMPAPYSVLDEYRLIND--NDSNYSKARLINNKGEIKDFSK 179 Query: 143 LADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEP 202 + +M + L ++++ L ++ ++ +++ + F Sbjct: 180 FG--LNKMDQLAIIRLLLKNKEELDDLTIE---DYFSESFLKSNFWT--FWRTMFAFENW 232 Query: 203 PRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPR---L 259 + L+ + ++ + ++V+ QY K + + + Sbjct: 233 HSLLELKLYMHRF--------LHAIDGLNDLSSLVFPKYNQYDTFVTPLRKFLQEKGVNI 284 Query: 260 QLNKVV----REIKYSPGGV--TVKTEDNS-----VYSADYVMVSA 294 LN +V I V + +D V DYV+V+ Sbjct: 285 HLNTLVKDLDIHINTEGKVVEGIITEQDGKEVKIPVGKNDYVIVTT 330 >5TUK-A nrPDB Length = 408 Score = 36.0 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 36/99 (36%), Gaps = 11/99 (11%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 +++V+GAG++G + L G + +L+ R G V++ V Sbjct: 27 KILVIGAGIAGPAVCYWLRRFGFSPILV--------ERCANLRKGGHAVDIRG--VAIDL 76 Query: 94 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVY 132 M I N ++ D +++E G + Sbjct: 77 AKSMGIYKKICNMRTQV-ELGRYVDAEGNILHEEKGERF 114 >6C6P-A nrPDB Length = 458 Score = 36.0 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGITDLLI---LEATDHIGGRMHKTNFAGINVELG-AN 87 P VI+VGAG+ G + A LS G +I L+ D I G + + +LG + Sbjct: 7 DPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLGD 66 Query: 88 WVEGVNGGKMN 98 VEG++ +N Sbjct: 67 TVEGLDAQVVN 77 >4TXK-A nrPDB Length = 615 Score = 35.6 bits (80), Expect = 0.055, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLI 61 A + +VVGAG G+ AA L+ G +L+ Sbjct: 80 QACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >2BRY-A nrPDB Length = 497 Score = 35.6 bits (80), Expect = 0.055, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 28 AATVGPRVIVVGAGMSGISAAKRLSEAGITDLLI 61 A + +VVGAG G+ AA L+ G +L+ Sbjct: 88 QACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >3BHF-A nrPDB Length = 390 Score = 35.6 bits (80), Expect = 0.057, Method: Composition-based stats. Identities = 13/27 (48%), Positives = 20/27 (74%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLI 61 VIVVGAG G++A +L++ G+ LL+ Sbjct: 7 VIVVGAGSMGMAAGYQLAKQGVKTLLV 33 >2QA2-A nrPDB Length = 499 Score = 35.2 bits (79), Expect = 0.058, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 31 VGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 VIVVGAG +G+ A L G+ D+++LE G F +E+ Sbjct: 11 SDASVIVVGAGPAGLMLAGELRLGGV-DVMVLEQLPQRTGESRGLGFTARTMEV 63 >1NHQ-A nrPDB Length = 447 Score = 35.2 bits (79), Expect = 0.060, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 4/46 (8%) Query: 28 AATVGPRV---IVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 TV P V +V+G+G GI AA+ ++AG + +++ D G Sbjct: 142 QKTVDPEVNNVVVIGSGYIGIEAAEAFAKAG-KKVTVIDILDRPLG 186 >1PS9-A nrPDB Length = 671 Score = 35.2 bits (79), Expect = 0.070, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 45/133 (33%), Gaps = 8/133 (6%) Query: 27 LAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA 86 L A + VVGAG +G++ A + G + + +A IGG+ + E Sbjct: 368 LPAVQKKNLAVVGAGPAGLAFAINAAARG-HQVTLFDAHSEIGGQFNIAKQIPGKEEFYE 426 Query: 87 N-----WVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRI 141 + V G + + L+ + + DG D V + Sbjct: 427 TLRYYRRMIEVTGVTLKLNHTVTADQLQAFDETILASGIVPRTPPIDG--IDHPKVLSYL 484 Query: 142 ELADSVEEMGEKL 154 ++ +G K+ Sbjct: 485 DVLRDKAPVGNKV 497 >1PJ5-A nrPDB Length = 830 Score = 34.8 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 20/33 (60%) Query: 31 VGPRVIVVGAGMSGISAAKRLSEAGITDLLILE 63 PR++++GAG+ G + A L G ++ +L+ Sbjct: 3 STPRIVIIGAGIVGTNLADELVTRGWNNITVLD 35 >6CMZ-A nrPDB Length = 466 Score = 34.8 bits (78), Expect = 0.085, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 2/36 (5%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 ++V+G G G AA R + GI +L+ D +GG Sbjct: 11 LLVIGGGPGGYVAAIRAGQLGIPTVLV--ERDRLGG 44 Score = 32.9 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHI 68 AT+ R++VVGAG G+ + G+ D+ ++EA + + Sbjct: 175 ATLPKRLVVVGAGYIGLELGIVYRKLGV-DVSVVEAAERV 213 >6ER9-A nrPDB Length = 549 Score = 34.8 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 3/60 (5%) Query: 27 LAATVGPRVI---VVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVE 83 + A + P V+ V+GAG GI A +L ++ + D GG + + G + Sbjct: 1 MTAQISPTVVDAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGGTWYWNRYPGALSD 60 >2GMH-A nrPDB Length = 584 Score = 34.8 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Query: 35 VIVVGAGMSGISAAKRLSEAGIT-----DLLILEATDHIGGRM 72 V++VGAG +G+SAA RL + + ++E HIG Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHT 80 >4A6N-B nrPDB Length = 398 Score = 34.8 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 21 LAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILE 63 + + + V ++G G G++ AK L + GI D+ + E Sbjct: 15 VPRGSHMNLLSDKNVAIIGGGPVGLTMAKLLQQNGI-DVSVYE 56 >3R9U-A nrPDB Length = 315 Score = 34.5 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 20/47 (42%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN 81 V ++G G +G+SA + G+ ++++ E G + Sbjct: 7 VAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYP 53 >3T14-A nrPDB Length = 437 Score = 34.5 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 36/253 (14%), Positives = 82/253 (32%), Gaps = 20/253 (7%) Query: 35 VIVVGAGMSGISAAKRLSEA--GITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGV 92 V+++GAG G+ AA + EA ++ ++ A D+ F N +G W + Sbjct: 7 VVILGAGTGGMPAAYEMKEALGSGHEVTLISANDY-------FQFVPSNPWVGVGW-KER 58 Query: 93 NGGKMNPIWPIVNSTLK-LRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEM- 150 + + + + D AQN+ DG DY+ + E + Sbjct: 59 DDIAFPIRHYVERKGIHFIAQSAEQIDAEAQNITLADGNTVHYDYLMIATGPKLAFENVP 118 Query: 151 -GEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMV------VDYYKFDYEFAEPP 203 + + + D + A + + Y++ A Sbjct: 119 GSDPHEGPVQSIATVDHAERAFAEYQALLREPGPIVIGAMAGASCFGPAYEYAMIVASDL 178 Query: 204 RVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNK 263 + +++ +P TF + + Q ++ G + + +++ NK Sbjct: 179 KKRGMRDKIPSFTFITSEPYIGHLGIQGVGDSKGILTKGLKEEGIEAYTNCKVTKVEDNK 238 Query: 264 V-VREIKYSPGGV 275 + V ++ + Sbjct: 239 MYVTQVDEKGETI 251 >5TUM-A nrPDB Length = 410 Score = 34.5 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 21 LAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILE-ATDHIGGRMHKTN 76 L GS + +++V+GAG++G + L G + +LI + A+ GG+ Sbjct: 14 LVPRGSHMMSKNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVR 70 >4CPD-A nrPDB Length = 347 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 14/91 (15%) Query: 19 LSLAQHGSLAATVGP--RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTN 76 LS A G + + P V V+GAG G+ A + G + +L A D I R+ Sbjct: 154 LSTAYGGLIQGQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKIL---AIDRIPERLE--- 207 Query: 77 FAGINVELGANWVEGVNGGKMNPIWPIVNST 107 LGA +N + NP+ + + T Sbjct: 208 ---RAASLGAI---PINAEQENPVRRVRSET 232 >4RG3-A nrPDB Length = 548 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 18 ALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRL-SEAGITDLLILEATDHIGGRMHKTN 76 +L + H + T +V+GAG GI A +L E G+T + +A D GG + Sbjct: 2 SLEASMHMTAQTTHTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKA-DGPGGTWYWNR 60 Query: 77 FAGINVE 83 + G + Sbjct: 61 YPGALSD 67 >3QJ4-A nrPDB Length = 342 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 5/62 (8%) Query: 34 RVIVVGAGMSGISAAKRLSEA--GITDLLILEATDHIGGRMHKTNFAGIN---VELGANW 88 +V++VGAGM+G A L G L + + D GGRM +LGA + Sbjct: 3 QVLIVGAGMTGSLCAALLRRQTSGPLYLAVWDKADDSGGRMTTACSPHNPQCTADLGAQY 62 Query: 89 VE 90 + Sbjct: 63 IT 64 >5MJK-A nrPDB Length = 327 Score = 34.1 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 26/116 (22%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKT----NFAGINVELGANWVE 90 V+++G+G +G++AA + + + LL+ GG+M+ T N+ G +G Sbjct: 27 VVIIGSGPAGMTAAMYTARSEMKTLLL--ERGVPGGQMNNTAEIENYPGYETIMGP---- 80 Query: 91 GVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADS 146 L ++ +N Y G+ D +K I D Sbjct: 81 ----------------ELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDE 120 >5J7X-A nrPDB Length = 549 Score = 34.1 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 24/49 (48%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVE 83 +++G+G SGI +L + + I EA IGG + + G V+ Sbjct: 15 ALIIGSGFSGIYLLHKLRDELKLKVKIFEAESDIGGTWNNNRYPGARVD 63 >6EJB-A nrPDB Length = 751 Score = 33.7 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 5/75 (6%) Query: 423 SDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEIL 482 D + G + G+ Y + P G ++ + T Y H G+ AE Sbjct: 404 LDYYLYGNYPAGTPGLRSYWENVYDEPDG-IHSLSDVTLTLY----HSFARLGLRRAETS 458 Query: 483 INCAQKKMCKYHVQG 497 ++ + C+Y+ G Sbjct: 459 LHTDGENSCRYYPMG 473 >1FOH-A nrPDB Length = 664 Score = 33.7 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 11/20 (55%), Positives = 16/20 (80%) Query: 35 VIVVGAGMSGISAAKRLSEA 54 V++VGAG +G+ AA+ LSE Sbjct: 10 VLIVGAGPAGLMAARVLSEY 29 >2HQM-A nrPDB Length = 479 Score = 33.7 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 46/146 (31%), Gaps = 31/146 (21%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 93 +V+VVGAG GI A G L++ G + + Sbjct: 187 KVVVVGAGYIGIELAGVFHGLGSETHLVI---------------------RGETVLRKFD 225 Query: 94 GGKMNPIWP-IVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGE 152 N I V + + + +NV + D ++ + + S++++ E Sbjct: 226 ECIQNTITDHYVKEGINVHKLSKIVK-VEKNV--------ETDKLKIHMNDSKSIDDVDE 276 Query: 153 KLSATLHASGRDDMSILAMQRLNEHQ 178 + S S +LN H Sbjct: 277 LIWTIGRKSHLGMGSENVGIKLNSHD 302 >1ZOV-A nrPDB Length = 386 Score = 33.3 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 13/27 (48%), Positives = 19/27 (70%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLI 61 VIVVGAG G++A L++ G+ LL+ Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLV 32 >2Q7V-A nrPDB Length = 325 Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 4/56 (7%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHK---TNFAGINVELGAN 87 V+++G G +G++AA A ++ LILE G NF G + Sbjct: 11 VVIIGGGPAGLTAAIYTGRAQLST-LILEKGMPGGQIAWSEEVENFPGFPEPIAGM 65 >2E5V-A nrPDB Length = 472 Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 26/53 (49%), Gaps = 3/53 (5%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGAN 87 + ++G+G++G+SA L AG LI + I G G+ +G++ Sbjct: 2 IYIIGSGIAGLSAGVALRRAGKKVTLI---SKRIDGGSTPIAKGGVAASVGSD 51 >2R9Z-A nrPDB Length = 463 Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 19 LSLAQHGSLAATVGPR-VIVVGAGMSGISAAKRLSEAGITDLLILEATDHI 68 L + G A P+ V ++GAG GI A L G +++ ++ D + Sbjct: 152 LGITSDGFFALQQQPKRVAIIGAGYIGIELAGLLRSFG-SEVTVVALEDRL 201 >4JNQ-A nrPDB Length = 345 Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 7/69 (10%) Query: 25 GSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGR----MHKTNFAGI 80 GS+ P VIV+G+G +G +AA + A + ++I A GG+ N+ G Sbjct: 20 GSMTQRHAP-VIVIGSGPAGYTAAIYAARAMLKPVVI--AGLQQGGQLMITTDVENYPGY 76 Query: 81 NVELGANWV 89 + W+ Sbjct: 77 AEPVQGPWM 85 >2VOU-A nrPDB Length = 397 Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Query: 31 VGPRVIVVGAGMSGISAAKRLSEAGITDLLILE 63 R+ VVG +SG++AA L +AG+ D+ + E Sbjct: 4 TTDRIAVVGGSISGLTAALMLRDAGV-DVDVYE 35 >4JDR-A nrPDB Length = 474 Score = 33.3 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Query: 34 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 +V+V+GAG +G SAA R ++ G+ +++ E + +GG Sbjct: 8 QVVVLGAGPAGYSAAFRCADLGLETVIV-ERYNTLGG 43 >1V59-A nrPDB Length = 478 Score = 32.9 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 V+++G G +G AA + ++ G + E +GG Sbjct: 8 VVIIGGGPAGYVAAIKAAQLGFNTACV-EKRGKLGG 42 >4X4J-A nrPDB Length = 507 Score = 32.9 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 4/48 (8%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINV 82 V++ GAG +G+ A L AGI +++LE + R ++ G Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIG-VVVLE---RLPARTGESRGLGFTA 68 >2YVG-A nrPDB Length = 408 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 24/57 (42%), Gaps = 1/57 (1%) Query: 16 LLALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRM 72 L L A+ R+++VG G+ G+ A AG+ + ++E + R Sbjct: 129 LRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGVH-VSLVETQPRLMSRA 184 >2A9F-A nrPDB Length = 398 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 6/57 (10%) Query: 8 GLLAVAALLLALSLAQHGSLAATVGPRVIVV-GAGMSGISAAKRLSEAGITDLLILE 63 ++ +AA+ +L L L ++ IVV G G +G+S ++L AG T + +++ Sbjct: 168 AIVVLAAIFNSLKL-----LKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVD 219 >5Z70-A nrPDB Length = 605 Score = 32.5 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 24/42 (57%), Gaps = 3/42 (7%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGI---TDLLILEATDHIGG 70 G + ++G+G++G+++A L G D+ IL+A GG Sbjct: 4 GRKAWIIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGG 45 >5UTH-A nrPDB Length = 319 Score = 32.5 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 28/198 (14%), Positives = 56/198 (28%), Gaps = 9/198 (4%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 VI++G+G +G +AA + A + L+ E T G M T Sbjct: 18 VIIIGSGPAGYTAAIYAARAQLKP-LVFEGTQFGGALMTTTEVENYP----GFREGITGP 72 Query: 95 GKMNPIWPI-VNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEK 153 M+ + + LR D L V G + + + +G Sbjct: 73 ELMDQMREQALRFGADLRMEDVDAVQLEGPVKTVVVGDETHQARAVILAMGAAARHLGVP 132 Query: 154 LSATLHASGRDDMSILAMQRLNEHQPN---GPATPVDMVVDYYKFDYEFAEPPRVTSLQN 210 L G + + G + ++ +F R + Sbjct: 133 GEEALTGMGVSTCATCDGFFFRDQDIVVVGGGDSAMEEATFLTRFARSVTLIHRRDEFRA 192 Query: 211 TVPLATFSDFGDDVYFVA 228 + + + + + F+ Sbjct: 193 SKIMLERARANEKITFLT 210 >3IWA-A nrPDB Length = 472 Score = 32.5 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 20 SLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHI 68 QH A V + ++VG G G+ A L++ D ++E D I Sbjct: 148 EFVQHAISAGEVS-KAVIVGGGFIGLEMAVSLADMWGIDTTVVELADQI 195 >4K22-A nrPDB Length = 365 Score = 32.1 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEAT 65 V +VG GM G++ A L +G+ + +LE Sbjct: 6 VAIVGGGMVGLAVACGLQGSGLR-VAVLEQR 35 >6J0Z-C nrPDB Length = 491 Score = 32.1 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 19/27 (70%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLI 61 V+VVGAG +G+ A L AG++ +++ Sbjct: 8 VVVVGAGPTGLMLAGELRLAGVSVVVL 34 >3IHG-A nrPDB Length = 535 Score = 32.1 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEAT 65 V+VVGAG+ G+S A L+ G+ +L++E Sbjct: 8 VLVVGAGLGGLSTAMFLARQGVR-VLVVERR 37 >6JDK-A nrPDB Length = 544 Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVE 83 ++VGAG +GI RL + G + + EA +GG + + G V+ Sbjct: 20 ALIVGAGFNGIYQLHRLRQEGFK-VRLFEAGADMGGIWYWNCYPGARVD 67 >3WSV-A nrPDB Length = 322 Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 24/57 (42%), Gaps = 11/57 (19%) Query: 27 LAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLIL----------EATDHIGGRMH 73 + T +V++VG G G S A + G+ + L+L EA D + G Sbjct: 1 MKKTSR-KVVIVGTGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAW 56 >6IK8-B nrPDB Length = 718 Score = 32.1 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 7/76 (9%) Query: 426 FYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYV------HGAYLSGIDSA 479 +YK TF+ P G + D G+++ GE H+ GY+ +Y + Sbjct: 601 WYKATFNA-PGGNDPLALDMASMGKGQIWINGEGVGRHWPGYIAQGDCSKCSYAGTFNEK 659 Query: 480 EILINCAQKKMCKYHV 495 + NC Q YHV Sbjct: 660 KCQTNCGQPSQRWYHV 675 >3ETC-A nrPDB Length = 580 Score = 32.1 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 26/202 (12%), Positives = 54/202 (26%), Gaps = 27/202 (13%) Query: 130 GVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMV 189 G + +IEL D + E + M + + + T Sbjct: 393 GSIGKPTPGYKIELMDRDGRLCEVGEE--GEIVINTMEGKPVGLFVHYGKDPERTEETWH 450 Query: 190 VDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTD- 248 YY + + F DD+ GY+ + + ++ Sbjct: 451 DGYYHTGDM--------AWMDEDGYLWFVGRADDI---IKTSGYKVGPFEVESALIQHPA 499 Query: 249 ------DKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSD 302 V ++ +V Y+P + V + + Sbjct: 500 VLECAITGVPDPVRGQVIKATIVLTKDYTPSDSLKNELQDHVKN-------VTAPYKYPR 552 Query: 303 LIQFKPKLPTWKVRAIYQFDMA 324 +I+F P+LP I + ++ Sbjct: 553 IIEFVPELPKTISGKIRRVEIR 574 >3ISH-A nrPDB Length = 311 Score = 32.1 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEA---TDHIGGRMHKTNFAGINVELGA 86 ++G G +G+SA + G+ + ++ E I G N+ G+ + Sbjct: 5 AIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSG 58 >6BRD-A nrPDB Length = 476 Score = 32.1 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 18/29 (62%), Gaps = 1/29 (3%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILE 63 VIVVG G +G+ A L G+ +L+LE Sbjct: 4 VIVVGGGPTGLMLAGELRLHGVR-VLVLE 31 Score = 29.1 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 27/84 (32%), Gaps = 3/84 (3%) Query: 235 AVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSA 294 AV + Q L + + ++ + + ++ GVTV D A YV+ Sbjct: 95 AVPQVITEQLLA---EHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCD 151 Query: 295 SLGVLQSDLIQFKPKLPTWKVRAI 318 L+ +V + Sbjct: 152 GGRSTVRKLLGVAFPGEPSRVETL 175 >4GCM-A nrPDB Length = 312 Score = 31.8 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 6/57 (10%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKT----NFAGINVELGAN 87 + ++GAG +G++AA S A + ++I GG+M T NF G + G + Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMI--ERGIPGGQMANTEEVENFPGFEMITGPD 63 >2ZBW-A nrPDB Length = 335 Score = 31.8 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 7/78 (8%) Query: 234 EAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI-------KYSPGGVTVKTEDNSVYS 286 E +Y +AG K + ++ V + + V T + Y+ Sbjct: 50 EKYIYDVAGFPKVYAKDLVKGLVEQVAPFNPVYSLGERAETLEREGDLFKVTTSQGNAYT 109 Query: 287 ADYVMVSASLGVLQSDLI 304 A V+++A +G + I Sbjct: 110 AKAVIIAAGVGAFEPRRI 127 >5GSN-A nrPDB Length = 453 Score = 31.8 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 39/101 (38%), Gaps = 18/101 (17%) Query: 206 TSLQNTVPLA--TFSDFGDDVYFVADQRGYEAV---VYYLAGQYLKTDDKSGKIVDPRLQ 260 L + P F+D+ + +F Y Y+ G+ K D V ++ Sbjct: 68 RYLWSNGPKEGLEFADYSFEEHFGKQIASYPPRAVLFDYIEGRVHKAD------VRKWIR 121 Query: 261 LNKVVREIKYSPG--GVTVKTEDN---SVYSA--DYVMVSA 294 N VR + Y TV ++ S YSA D+V+ ++ Sbjct: 122 FNSPVRWVSYDAETAKFTVTAHNHETDSTYSAAFDHVICAS 162 >5YGQ-A nrPDB Length = 342 Score = 31.8 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 41/101 (40%), Gaps = 9/101 (8%) Query: 27 LAATVGPRVIVVGAGMSGISAAKRLSEAGITDLL--ILEATDHIGGRMHKTNFAGINVEL 84 + T+ V++VGAG G+ A L G+ D+ +++ D +GG+ + ++ Sbjct: 1 MTETIKTDVLIVGAGPCGLFAVFEL---GLLDVKAHLVDILDKVGGQCAELYPEKPIYDI 57 Query: 85 GANWV---EGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQ 122 + G+ M I P N T L + + + Sbjct: 58 PGIPMVTGHGLTEALMEQIKPF-NPTFHLSEMVENVEKIGD 97 >4YKF-A nrPDB Length = 521 Score = 31.8 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 1/32 (3%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGITDLLILE 63 G RV V+G G SG+ AA L+ + + +LE Sbjct: 355 GKRVAVIGGGNSGVEAAIDLAGI-VEHVTLLE 385 >1FL2-A nrPDB Length = 310 Score = 31.8 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 1/32 (3%) Query: 32 GPRVIVVGAGMSGISAAKRLSEAGITDLLILE 63 G RV V+G G SG+ AA L+ + + +LE Sbjct: 144 GKRVAVIGGGNSGVEAAIDLAGI-VEHVTLLE 174 >2VHY-A nrPDB Length = 377 Score = 31.8 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 18/90 (20%) Query: 25 GSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEAT-DHIG-------GRMHKTN 76 G + V+V+GAG +G +AA+ + G + +L+ D + GR+H Sbjct: 161 GGVPGVEPADVVVIGAGTAGYNAARIANGMG-ATVTVLDINIDKLRQLDAEFCGRIHTRY 219 Query: 77 FAGINVE---------LGANWVEGVNGGKM 97 + +E +GA V G K+ Sbjct: 220 SSAYELEGAVKRADLVIGAVLVPGAKAPKL 249 >5JEA-H nrPDB Length = 316 Score = 31.4 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 27/69 (39%), Gaps = 9/69 (13%) Query: 63 EATDHIGGRMHKTNFAGINVELGANWVE-------GVNGGKMNPIWPIVNSTLKLRNFRS 115 E DH+ GR+ + V++G + GG + + L++R+F Sbjct: 64 ETGDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSE--SDELQMRSFLK 121 Query: 116 DFDYLAQNV 124 + D L V Sbjct: 122 EGDLLNAEV 130 >4OO1-H nrPDB Length = 363 Score = 31.4 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 27/69 (39%), Gaps = 9/69 (13%) Query: 63 EATDHIGGRMHKTNFAGINVELGANWVE-------GVNGGKMNPIWPIVNSTLKLRNFRS 115 E DH+ GR+ + V++G + GG + + L++R+F Sbjct: 111 ETGDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSE--SDELQMRSFLK 168 Query: 116 DFDYLAQNV 124 + D L V Sbjct: 169 EGDLLNAEV 177 >5NCC-A nrPDB Length = 594 Score = 31.4 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 17/29 (58%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEA 64 I+VG G + A RLS G +L+LEA Sbjct: 27 ILVGGGTAACVLANRLSADGSKRVLVLEA 55 >4Z2R-A nrPDB Length = 592 Score = 31.4 bits (69), Expect = 0.96, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATD-HIGGRMHKTN 76 V++VGAG +G +A L+ GI L+I G R H N Sbjct: 15 VLIVGAGPAGAMSATLLASLGIRSLMINRWRSTSPGPRSHIIN 57 >5ZYN-B nrPDB Length = 471 Score = 31.4 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 26/42 (61%) Query: 29 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 A++ V+V+G+G++G++ + RL +++L+ IGG Sbjct: 1 ASMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGG 42 >4MOP-A nrPDB Length = 633 Score = 31.4 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 44/103 (42%), Gaps = 4/103 (3%) Query: 35 VIVVGAGMSGISAAKRLSEAGIT----DLLILEATDHIGGRMHKTNFAGINVELGANWVE 90 V++VG+G G + A+ L AG D+ +++ IG T N++ N ++ Sbjct: 49 VVIVGSGPIGCTYARELVGAGYKVAMFDIGEIDSGLKIGAHKKNTVEYQKNIDKFVNVIQ 108 Query: 91 GVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYD 133 G P+ +V TL ++++ ++ E + + Sbjct: 109 GQLMSVSVPVNTLVVDTLSPTSWQASTFFVRNGSNPEQDPLRN 151 >3AB1-A nrPDB Length = 360 Score = 31.4 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 35/104 (33%), Gaps = 13/104 (12%) Query: 37 VVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGA---------- 86 ++G G +GI AA + I+ I+E+ +GG++ ++ Sbjct: 19 IIGGGPTGIFAAFQCGMNNIS-CRIIESMPQLGGQLAALYPEKHIYDVAGFPEVPAIDLV 77 Query: 87 --NWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKED 128 W + + V KL + + NVY+ Sbjct: 78 ESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRSR 121 >2A87-A nrPDB Length = 335 Score = 31.4 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 26/69 (37%), Gaps = 5/69 (7%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 VIV+G+G +G +AA + A + L+ E T G M T+ Sbjct: 17 VIVIGSGPAGYTAALYAARAQLAP-LVFEGTSFGGALMTTTDVENYP----GFRNGITGP 71 Query: 95 GKMNPIWPI 103 M+ + Sbjct: 72 ELMDEMREQ 80 >5EZ7-A nrPDB Length = 392 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 26 SLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 70 S+ + +++VG G++G+ RL AG +L+ A+ +GG Sbjct: 1 SMPQALSTDILIVGGGIAGLWLNARLRRAGYATVLVESAS--LGG 43 >1GPE-A nrPDB Length = 587 Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 19/28 (67%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILE 63 I+ G G++G++ A +L+E +L++E Sbjct: 28 IIAGGGLTGLTVAAKLTENPKIKVLVIE 55 >1GAL-A nrPDB Length = 583 Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 20/29 (68%) Query: 36 IVVGAGMSGISAAKRLSEAGITDLLILEA 64 I+ G G++G++ A RL+E +L++E+ Sbjct: 23 IIAGGGLTGLTTAARLTENPNISVLVIES 51 >4B3J-A nrPDB Length = 736 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Query: 22 AQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLL---ILEATDHIGGRMHKTNFA 78 ++ + T R+ V+GAGM G A ++AG +L LEA G+ + Sbjct: 331 SRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAK--GKGYSEKLE 388 Query: 79 GINVELG 85 +E G Sbjct: 389 AKALERG 395 >4HA6-A nrPDB Length = 508 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 21/32 (65%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATD 66 +++VG G +G A RLSE + +L++EA + Sbjct: 4 IVIVGGGSAGSLLAARLSEDPDSRVLLIEAGE 35 >6HNS-A nrPDB Length = 454 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 45/208 (21%), Positives = 75/208 (36%), Gaps = 27/208 (12%) Query: 32 GPRVIVVGAGMSGISAAKRLS-----EAGITDLLILEATDHIGGRMHKTNFAGINVELGA 86 RV ++GAG G++ + A I +L+ E GG M + E G Sbjct: 2 NTRVAIIGAGPCGLAQLRAFQSAAAKGAAIPELVCFEKQSDWGG-MWNYTWRTGVDEHG- 59 Query: 87 NWVEGVNGGKMNPIWPIVNST-LKLRNFRSDFDYLAQNV--YKEDGGVYDEDYVQKRIEL 143 E V+G +W L+ ++ D ++ + + Y ++D Y++ R+E Sbjct: 60 ---EPVHGSMYRYLWSNGPKECLEFADYTFD-EHFGRPIGSYPPREVLWD--YIKGRVEK 113 Query: 144 ADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPP 203 A + + + + + D+ S L + +H N T FDY Sbjct: 114 AGVRDYI--RFNTAVRQVSYDETSGLFSVTVQDHSNNRVYT--------ETFDYVVNACG 163 Query: 204 RVTSLQNTVPLATFSDFGDDVYFVADQR 231 S NT F FG V D R Sbjct: 164 HF-STPNTPYFEGFERFGGRVLHAHDFR 190 >6GAR-A nrPDB Length = 349 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 40/95 (42%), Gaps = 6/95 (6%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 94 V V+G G +G+ +A S I+E H+GG++H + ++G + V G Sbjct: 9 VTVIGGGPAGLYSAF-YSGLREMRTKIIEFHPHLGGKIHVYP-EKMIWDVGG--LLPVTG 64 Query: 95 GKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDG 129 K+ I +V L + + + +DG Sbjct: 65 DKL--IEQLVQQGLTFKPEVVLDTKVESIIRNQDG 97 >3CP8-A nrPDB Length = 641 Score = 30.2 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 14/27 (51%), Positives = 18/27 (66%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLI 61 VIVVGAG +G AA ++ G+ LLI Sbjct: 24 VIVVGAGHAGCEAALAVARGGLHCLLI 50 >2VDC-G nrPDB Length = 456 Score = 30.2 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 19 LSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDH 67 + ++GSL A G V+V+G G + + + G T + L D Sbjct: 252 VEAYENGSLNA-AGKHVVVLGGGDTAMDCVRTAIRQGATSVKCLYRRDR 299 >5KOX-A nrPDB Length = 476 Score = 29.8 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%), Gaps = 1/50 (2%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVEL 84 VI+ G G +G+ A L G+ + +LE ++E+ Sbjct: 7 VIIAGGGPTGLMLAGELRLHGVRTV-VLEKEPTPNQHSRSRGLHARSIEV 55 >3PLN-A nrPDB Length = 424 Score = 29.8 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 22/162 (13%), Positives = 49/162 (30%), Gaps = 7/162 (4%) Query: 237 VYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVY-SADYVMVSAS 295 + + + + K IVD +Q + P T+ + Y +ADYV+++ Sbjct: 64 LDIVQAKVDMLNQKISPIVDKEIQ-----EYLAEKPLNFRATTDKHDAYRNADYVIIATP 118 Query: 296 LGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRG 355 F +R + + + I P F + K R Sbjct: 119 TD-YDPKTNYFNTSTVEAVIRDVTEINPNAVMIIKSTIPVGFTRDIKERLGIDNVIFSPE 177 Query: 356 YYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEI 397 + + + +++ + R + + K +I Sbjct: 178 FLREGRALYDNLHPSRIVIGERSARAERFADLLKEGAIKQDI 219 >5IXB-A nrPDB Length = 108 Score = 29.5 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 17/49 (34%), Gaps = 3/49 (6%) Query: 321 FDMAVYTKIFLKFP---RKFWPEGKGREFFLYASSRRGYYGVWQEFEKQ 366 +F K R FW +++ ++R GY+ E Q Sbjct: 41 IHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQ 89 >2EEZ-A nrPDB Length = 369 Score = 29.5 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 30/80 (37%), Gaps = 18/80 (22%) Query: 35 VIVVGAGMSGISAAKRLSEAGITDLLILEATDH--------IGGRMHK---------TNF 77 V+++G G G +AAK G + IL+ GGR+ + Sbjct: 169 VVILGGGTVGTNAAKIALGMG-AQVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKSV 227 Query: 78 AGINVELGANWVEGVNGGKM 97 ++ +GA V G K+ Sbjct: 228 QHADLLIGAVLVPGAKAPKL 247 >5AVM-A nrPDB Length = 333 Score = 29.5 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 13/64 (20%) Query: 18 ALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLS------------EAGITDLLILEAT 65 AL A+ ++AAT P V+ G+ AA RL G LL LEA Sbjct: 16 ALRRARE-AIAATYTPEVLRGMGAFGGLYAASRLKALEEPVLVATTDGVGTKTLLALEAG 74 Query: 66 DHIG 69 D G Sbjct: 75 DVSG 78 >3NTA-A nrPDB Length = 574 Score = 29.5 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 27/83 (32%), Gaps = 9/83 (10%) Query: 244 YLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKT-EDNSVYSADYVMVSASLGVLQSD 302 L+T + + +++ V I + VTV+ D S Y Y + +L Sbjct: 60 VLQTPESFKARFNVEVRVKHEVVAIDRAAKLVTVRRLLDGSEYQESYDTL-----LLSPG 114 Query: 303 LIQFKPKLPTWKV---RAIYQFD 322 P +P ++ Sbjct: 115 AAPIVPPIPGVDNPLTHSLRNIP 137 >5US9-A nrPDB Length = 541 Score = 29.5 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 40/121 (33%), Gaps = 16/121 (13%) Query: 230 QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVK---TEDNSVYS 286 Q GY V++ LA V+ + L ++ S V TE + Sbjct: 190 QYGYIPVIHELAEMEDSN------AVEKAICLQIPFFMLENSDHEVLRTGESTEFTFNFD 243 Query: 287 ADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFD----MAVYTKIFLKFPRKFWPEGK 342 +++ + + F P +PT + + I + + ++I W G Sbjct: 244 CEWI---NNERAYIPPGLMFNPLVPTRRAQYIRRNNNPQTAESTSRIAPYAKPTSWMTGP 300 Query: 343 G 343 G Sbjct: 301 G 301 >5TWC-A nrPDB Length = 344 Score = 28.7 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 34/93 (36%), Gaps = 9/93 (9%) Query: 207 SLQNTVPLATFSDFGDDVYFVADQRGY-EAVVYYLAG-------QYLKTDDKSGKIVDPR 258 S + + R Y E +++ + G + LK K G P Sbjct: 17 SFYAGLRDMSVRLIDVQSELGGKMRIYPEKIIWDIGGIAPKPCHEILKDTIKQGLYFKPE 76 Query: 259 LQLNKVVREIKYSPG-GVTVKTEDNSVYSADYV 290 + LN+ V +I+ V+TE +Y++ V Sbjct: 77 VHLNERVVDIRKKAERHFEVETEAGEIYTSKAV 109 >2QA1-A nrPDB Length = 500 Score = 28.7 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 12/21 (57%), Positives = 14/21 (66%) Query: 35 VIVVGAGMSGISAAKRLSEAG 55 VIVVGAG +G+ A L AG Sbjct: 14 VIVVGAGPAGMMLAGELRLAG 34 >1L1J-A nrPDB Length = 239 Score = 28.3 bits (61), Expect = 9.1, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 23/74 (31%), Gaps = 10/74 (13%) Query: 217 FSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVT 276 + + +F G+E V L ++ + + +T Sbjct: 34 YFEQFFKKWFGELPPGFERQVASLGSGFIFDPEGYILTN----------YHVVGGADNIT 83 Query: 277 VKTEDNSVYSADYV 290 V D S Y A+Y+ Sbjct: 84 VTMLDGSKYDAEYI 97 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.117 0.276 Lambda K H 0.267 0.0363 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,639,901 Number of Sequences: 36641 Number of extensions: 617189 Number of successful extensions: 2557 Number of sequences better than 10.0: 187 Number of HSP's better than 10.0 without gapping: 176 Number of HSP's successfully gapped in prelim test: 106 Number of HSP's that attempted gapping in prelim test: 2158 Number of HSP's gapped (non-prelim): 357 length of query: 500 length of database: 10,336,785 effective HSP length: 101 effective length of query: 399 effective length of database: 6,636,044 effective search space: 2647781556 effective search space used: 2647781556 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.3 bits)