BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O60825 (505 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5HTK-A nrPDB 1053 0.0 5HR5-A nrPDB 1003 0.0 2DWP-A nrPDB 715 0.0 4D4L-A nrPDB 694 0.0 1K6M-A nrPDB 655 0.0 2BIF-A nrPDB 652 0.0 1C7Z-A nrPDB 330 8e-91 4IJ6-A nrPDB 62 6e-10 6NRU-A nrPDB 56 4e-08 1RII-A nrPDB 54 1e-07 3KKK-A nrPDB 52 5e-07 4EO9-A nrPDB 51 1e-06 5PGM-D nrPDB 49 4e-06 3PGM-A nrPDB 49 5e-06 1E58-A nrPDB 48 1e-05 4PZA-A nrPDB 44 2e-04 5VVE-A nrPDB 43 3e-04 4ODI-A nrPDB 43 4e-04 1FZT-A nrPDB 41 0.001 3D8H-A nrPDB 38 0.011 3GW8-A nrPDB 37 0.016 4C0E-A nrPDB 34 0.13 5L3R-A nrPDB 33 0.23 4XRP-A nrPDB 33 0.28 3LVQ-E nrPDB 33 0.31 5Y64-B nrPDB 33 0.37 5XBP-A nrPDB 33 0.39 1EG9-A nrPDB 32 0.46 4EMB-A nrPDB 32 0.51 3UHP-A nrPDB 32 0.57 3DM5-A nrPDB 32 0.65 2A5F-A nrPDB 32 0.68 3HJG-A nrPDB 32 0.80 6BBQ-A nrPDB 32 0.89 4C5U-A nrPDB 30 1.7 2RHQ-B nrPDB 30 1.7 2YVU-A nrPDB 30 2.6 2BMQ-A nrPDB 30 2.9 4CMR-A nrPDB 30 3.0 2V3C-C nrPDB 30 3.6 2JGP-A nrPDB 29 4.2 3CVR-A nrPDB 28 9.1 >5HTK-A nrPDB Length = 505 Score = 1053 bits (2723), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 1 MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTR 60 MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTR Sbjct: 1 MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTR 60 Query: 61 YLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEE 120 YLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEE Sbjct: 61 YLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEE 120 Query: 121 NGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPE 180 NGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPE Sbjct: 121 NGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPE 180 Query: 181 RNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVY 240 RNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVY Sbjct: 181 RNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVY 240 Query: 241 YLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVW 300 YLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVW Sbjct: 241 YLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVW 300 Query: 301 TSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 TSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY Sbjct: 301 TSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 Query: 361 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTI 420 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTI Sbjct: 361 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTI 420 Query: 421 FKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR 480 FKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR Sbjct: 421 FKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR 480 Query: 481 NYSVGSRPLKPLSPLRAQDMQEGAD 505 NYSVGSRPLKPLSPLRAQDMQEGAD Sbjct: 481 NYSVGSRPLKPLSPLRAQDMQEGAD 505 >5HR5-A nrPDB Length = 531 Score = 1003 bits (2592), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/507 (94%), Positives = 498/507 (98%), Gaps = 3/507 (0%) Query: 1 MSG--ASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKL 58 MSG ASSSEQNNNSYETK +LR+SEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKL Sbjct: 1 MSGNPASSSEQNNNSYETKA-SLRISEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKL 59 Query: 59 TRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLT 118 TRYLNWIGVPTKVFNLGVYRR+AVKSYKSYDFFRHDNEEAMKIRKQCALVAL+DVKAYLT Sbjct: 60 TRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLT 119 Query: 119 EENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDY 178 EE+GQIAVFDATNTTRERRD+ILNFAE+NSFKVFFVESVCDDPDVIAANILEVKVSSPDY Sbjct: 120 EESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDY 179 Query: 179 PERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKI 238 PERNRENVM+DFLKRIECYKVTY+PLDPD++DKDLSFIKVINVGQRFLVN+VQDYIQSKI Sbjct: 180 PERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKI 239 Query: 239 VYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLK 298 VYYLMNIHV PRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEI DLK Sbjct: 240 VYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLK 299 Query: 299 VWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLY 358 VWTSQLKRTIQTAESLGV YEQWKILNEIDAGVCEEMTYAEI+++YP+EFALRD+EKYLY Sbjct: 300 VWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLY 359 Query: 359 RYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH 418 RYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH Sbjct: 360 RYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH 419 Query: 419 TIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRR 478 TIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRR Sbjct: 420 TIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRR 479 Query: 479 PRNYSVGSRPLKPLSPLRAQDMQEGAD 505 PRNYSVGSRPL+PLSPLRA D QEGAD Sbjct: 480 PRNYSVGSRPLQPLSPLRALDTQEGAD 506 >2DWP-A nrPDB Length = 520 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/452 (73%), Positives = 390/452 (86%), Gaps = 2/452 (0%) Query: 29 SWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSY 88 S +TNSPT+IVM+GLPARGKTY+SKKLTRYLNWIGVPTKVFN+G YRREAVK Y SY Sbjct: 26 SCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSY 85 Query: 89 DFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNS 148 +FFR DNEEAMK+RKQCAL AL DVK+YL +E GQIAVFDATNTTRERR MIL+FA++N Sbjct: 86 NFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKEND 145 Query: 149 FKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDN 208 FK FF+ESVCDDP V+A+NI+EVK+SSPDY + N M+DF+KRI CY+ +Y+PLDPD Sbjct: 146 FKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDK 205 Query: 209 YDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKI 268 D+DLS IKVI+VG+RFLVNRVQD+IQS+IVYYLMNIHVQPRTIYLCRHGE+E NL G+I Sbjct: 206 CDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRI 265 Query: 269 GGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEID 328 GGDSGLS RGK+FA AL KF+EEQ + DL+VWTSQLK TIQTAE+L +PYEQWK LNEID Sbjct: 266 GGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEID 325 Query: 329 AGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLV 388 AGVCEE+TY EI YPEE+ALR+Q+KY YRYP GESYQDLVQRLEPVIMELERQ NVLV Sbjct: 326 AGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLV 385 Query: 389 ISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDK 448 I HQAV+RCLLAYFLDK A+E+PYL+CPLHT+ KLTPVAYGC+VE+I LNVE+V THR++ Sbjct: 386 ICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRER 445 Query: 449 PTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR 480 + + K P+ MRRNS TPL+S ++PR Sbjct: 446 -SEDAKKGPNPL-MRRNSVTPLASPEPTKKPR 475 >4D4L-A nrPDB Length = 449 Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/415 (77%), Positives = 370/415 (89%) Query: 34 MTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRH 93 +TNSPT+IVM+GLPARGKTY+SKKLTRYLNWIGVPTKVFN+G YRREAVK Y SY+FFR Sbjct: 31 LTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRP 90 Query: 94 DNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFF 153 DNEEAMK+RKQCAL AL DVK+YL +E GQIAVFDATNTTRERR MIL+FA++N FK FF Sbjct: 91 DNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFF 150 Query: 154 VESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDL 213 +ESVCDDP V+A+NI+EVK+SSPDY + N M+DF+KRI CY+ +Y+PLDPD D+DL Sbjct: 151 IESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDL 210 Query: 214 SFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSG 273 S IKVI+VG+RFLVNRVQD+IQS+IVYYLMNIHVQPRTIYLCRHGE+E NL G+IGGDSG Sbjct: 211 SLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSG 270 Query: 274 LSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCE 333 LS RGK+FA AL KF+EEQ + DL+VWTSQLK TIQTAE+L +PYEQWK LNEIDAGVCE Sbjct: 271 LSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCE 330 Query: 334 EMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQA 393 E+TY EI YPEE+ALR+Q+KY YRYP GESYQDLVQRLEPVIMELERQ NVLVI HQA Sbjct: 331 ELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQA 390 Query: 394 VMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDK 448 V+RCLLAYFLDK A+E+PYL+CPLHT+ KLTPVAYGC+VE+I LNVE+V THR++ Sbjct: 391 VLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRER 445 >1K6M-A nrPDB Length = 432 Score = 655 bits (1689), Expect = 0.0, Method: Compositional matrix adjust. Identities = 305/416 (73%), Positives = 364/416 (87%), Gaps = 2/416 (0%) Query: 36 NSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDN 95 NSPT+++M+GLPARGKTY+S KLTRYLN+IG PTKVFNLG YRREAV SYK+Y+FF DN Sbjct: 1 NSPTMVIMVGLPARGKTYISTKLTRYLNFIGTPTKVFNLGQYRREAV-SYKNYEFFLPDN 59 Query: 96 EEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVE 155 EA++IRKQCAL AL+DV YL+ E G +AVFDATNTTRERR +IL FA+++ +KVFF+E Sbjct: 60 MEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIE 119 Query: 156 SVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSF 215 S+C+DP +IA NI +VK+ SPDY + +RE V+EDFLKRIECY+V Y+PLD + D LS+ Sbjct: 120 SICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLD-EELDSHLSY 178 Query: 216 IKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLS 275 IK+ +VG R++VNRVQD+IQS+ VYYLMNIHV PR+IYLCRHGESE N+ G+IGGDSGLS Sbjct: 179 IKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLS 238 Query: 276 VRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEM 335 VRGKQ+A AL F++ Q I+ LKV+TS++KRTIQTAE+LGVPYEQ+K LNEIDAGVCEEM Sbjct: 239 VRGKQYAYALANFIQSQGISSLKVFTSRMKRTIQTAEALGVPYEQFKALNEIDAGVCEEM 298 Query: 336 TYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVM 395 TY EI++ YPEEFALRDQ+KY YRYP GESY+DLVQRLEPVIMELERQ NVLVI HQAVM Sbjct: 299 TYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVM 358 Query: 396 RCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTN 451 RCLLAYFLDK ++ELPYL+CPLHT+ KLTPVAYGCKVE+I LNVEAVNTHR+KP N Sbjct: 359 RCLLAYFLDKSSEELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPEN 414 >2BIF-A nrPDB Length = 469 Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/438 (69%), Positives = 366/438 (83%), Gaps = 5/438 (1%) Query: 14 YETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFN 73 Y P L S++ MTN PTLIVM+GLPARGKTY+SKKLTRYLN+IGVPT+ FN Sbjct: 19 YSNGRPALHASQRGVC----MTNCPTLIVMVGLPARGKTYISKKLTRYLNFIGVPTREFN 74 Query: 74 LGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTT 133 +G YRR+ VK+YKS++FF DNEE +KIRKQCAL AL DV+ +L+EE G +AVFDATNTT Sbjct: 75 VGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEGGHVAVFDATNTT 134 Query: 134 RERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKR 193 RERR MI NF EQN +K FFVES+C DP+VIAANI++VK+ SPDY R+ + EDF++R Sbjct: 135 RERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRR 194 Query: 194 IECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIY 253 IECY+ +Y LD + D+DLS+IK+++VGQ ++VNRV D+IQS+IVYYLMNIHV PR+IY Sbjct: 195 IECYENSYESLDEEQ-DRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIY 253 Query: 254 LCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAES 313 LCR GESE NL G+IGGD GLS RG++F++ L +F+ +Q I DLKV+TSQ+KRTIQTAE+ Sbjct: 254 LCRAGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVFTSQMKRTIQTAEA 313 Query: 314 LGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRL 373 L VPYEQ+K+LNEIDAGVCEEMTY EI+ YP EFALRDQ+KY YRYP GESY+DLVQRL Sbjct: 314 LSVPYEQFKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRL 373 Query: 374 EPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVE 433 EPVIMELERQ NVLVI HQAVMRCLLAYFLDK A+ELPYL+CPLHT+ KLTPVAYGCKVE Sbjct: 374 EPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLKLTPVAYGCKVE 433 Query: 434 TIKLNVEAVNTHRDKPTN 451 +I LNV AVNTHRD+P N Sbjct: 434 SIFLNVAAVNTHRDRPQN 451 >1C7Z-A nrPDB Length = 191 Score = 330 bits (846), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 153/190 (80%), Positives = 169/190 (88%) Query: 250 RTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 R+IYLCRHGESE NL G+IGGDSGLS RGKQ+A AL F+ Q I+ LKVWTS +KRTIQ Sbjct: 2 RSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQGISSLKVWTSHMKRTIQ 61 Query: 310 TAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDL 369 TAE+LGVPYEQWK LNEIDAGVCEEMTY EI++ YPEEFALRDQ+KY YRYP GESY+DL Sbjct: 62 TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL 121 Query: 370 VQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYG 429 VQRLEPVIMELERQ NVLVI HQAVMRCLLAYFLDK +DELPYL+CPLHT+ KLTPVAYG Sbjct: 122 VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG 181 Query: 430 CKVETIKLNV 439 C+VE+I LNV Sbjct: 182 CRVESIYLNV 191 >4IJ6-A nrPDB Length = 211 Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 52/178 (29%), Positives = 89/178 (50%), Gaps = 19/178 (10%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT-- 307 + L R ESE+N +G+ G D LS RGK+ A+ L + L + + +++S LKRT Sbjct: 4 LILVRAAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHLD--VIYSSPLKRTYL 61 Query: 308 --IQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGES 365 ++ AE+ + + + EID G+ M E+ ++YPE+F +E + + GGES Sbjct: 62 TALEIAEAKNLEVIKEDRIIEIDHGMWSGMLVEEVMEKYPEDFRRWVEEPHKVEFQGGES 121 Query: 366 YQDLVQRLEPVIMELERQG---NVLVISHQAVMRCL--------LAYFLDKGADELPY 412 + R++ + E+ ++ V+V+SH MR + L+ F G D Y Sbjct: 122 LASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWSFGCDNASY 179 >6NRU-A nrPDB Length = 206 Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 52/180 (28%), Positives = 86/180 (47%), Gaps = 27/180 (15%) Query: 252 IYLCRHGESEFNLLGKIGGDSG--LSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 ++L RHGE++ N+ G G + L+ RG + AQ L L++ DL V S+L+R Sbjct: 6 LWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSF-DL-VLCSELERAQH 63 Query: 310 TAESL----GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKY-------LY 358 TA + +P I+ E++ EM + + E R+ + D E Y + Sbjct: 64 TARLVLSDRQLPVH---IIPELN-----EMFFGDWEMRHHRDLMQEDAENYSAWCNDWQH 115 Query: 359 RYP-GGESYQDLVQRLEPVIMEL---ERQGNVLVISHQAVMRCLLAYFLDKGADELPYLR 414 P GE +Q QR+E I L + N+L++SHQ V+ L+A + A+ + + R Sbjct: 116 AIPTNGEGFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARLIGMPAESMWHFR 175 >1RII-A nrPDB Length = 265 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 54/203 (26%), Positives = 86/203 (42%), Gaps = 37/203 (18%) Query: 251 TIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 ++ L RHGES++N L G D GL+ +G+ A + + E ++ ++TS L+R I Sbjct: 6 SLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAI 65 Query: 309 QT-------AESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE--FALR-------- 351 T A+ L +P + LNE G + + AE + RY EE A R Sbjct: 66 TTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPP 125 Query: 352 ----------DQEKYLYRYPGG---ESYQDLVQRLEP-----VIMELERQGNVLVISHQA 393 D + GG E D+V R P ++ +L VL+++H Sbjct: 126 PIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGN 185 Query: 394 VMRCLLAYFLDKGADELPYLRCP 416 +R L+ + DE+ L P Sbjct: 186 SLRALVKHLDQMSDDEIVGLNIP 208 >3KKK-A nrPDB Length = 258 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 40/106 (37%), Positives = 56/106 (52%), Gaps = 9/106 (8%) Query: 251 TIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 T+ L RHGES +N K G D LS +G++ A A K+L+E+ V+TS LKR I Sbjct: 13 TLVLLRHGESTWNKENKFTGWTDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSVLKRAI 72 Query: 309 -------QTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE 347 +TA+ L VP + LNE G + + +E K+Y EE Sbjct: 73 CTAWNVLKTADLLHVPVVKTWRLNERHCGSLQGLNKSETAKKYGEE 118 >4EO9-A nrPDB Length = 268 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 53/203 (26%), Positives = 84/203 (41%), Gaps = 37/203 (18%) Query: 251 TIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 T+ L RHGES++N G D GL+ +G+ A + L E + ++TS L+R I Sbjct: 29 TLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLRRAI 88 Query: 309 -------QTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYP 361 TA+ L +P + LNE G + + A + RY EE + + Y P Sbjct: 89 TTAHLALDTADWLWIPVRRSWRLNERHYGALQGLDKAVTKARYGEERFMAWRRSYDTPPP 148 Query: 362 -------------------GG----ESYQDLVQRLEP-----VIMELERQGNVLVISHQA 393 GG E D+V R P ++ +L VL+++H Sbjct: 149 PIEKGSEFSQDADPRYTDIGGGPLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGN 208 Query: 394 VMRCLLAYFLDKGADELPYLRCP 416 +R L+ + + DE+ L P Sbjct: 209 SLRALVKHLDEMSDDEVVGLNVP 231 >5PGM-D nrPDB Length = 246 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 50/190 (26%), Positives = 82/190 (43%), Gaps = 39/190 (20%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHG+SE+N G D LS +G+Q A + L+E+++ ++TS+L R IQ Sbjct: 3 LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQ 62 Query: 310 T-------AESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE--------------- 347 T A+ L +P + LNE G + AE K++ EE Sbjct: 63 TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPP 122 Query: 348 ------FALRDQEKYLY----RYPGGESYQDLVQRLEP-----VIMELERQGNVLVISHQ 392 F+ + E+Y Y P ES ++ RL P + +L V++ +H Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHG 182 Query: 393 AVMRCLLAYF 402 +R L+ + Sbjct: 183 NSLRGLVKHL 192 >3PGM-A nrPDB Length = 244 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 89/208 (42%), Gaps = 39/208 (18%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHG+SE+N G D LS +G+Q A + L+E+ + L +TS+L R IQ Sbjct: 3 LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKGVNVLVDYTSKLSRAIQ 62 Query: 310 T-------AESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE--------------- 347 T A+ L +P + LNE G + A+ K++ EE Sbjct: 63 TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAQTLKKFGEEKFNTYRRSFDVPPPP 122 Query: 348 ------FALRDQEKYLY----RYPGGESYQDLVQRLEP----VIMELERQGNVLVISHQA 393 F+ + E+Y Y P ES ++ RL P VI +L + + ++ +H Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKLVGKTS-MIAAHGN 181 Query: 394 VMRCLLAYFLDKGADELPYLRCPLHTIF 421 +R L+ + ++ L P TI Sbjct: 182 SLRGLVKHLEGISDADIAKLNIPPGTIL 209 >1E58-A nrPDB Length = 249 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 89/205 (43%), Gaps = 41/205 (20%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHGES++N + G D LS +G A+A K L+E+ + +TS LKR I Sbjct: 5 LVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIH 64 Query: 310 T-------AESLGVPYEQ-WKILNEIDAGVCEEMTYAEIEKRYPEE--------FALRDQ 353 T + +P E+ WK LNE G + + AE ++Y +E FA+ Sbjct: 65 TLWNVLDELDQAWLPVEKSWK-LNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPP 123 Query: 354 E--KYLYRYPGG---------------ESYQDLVQRLEP-----VIMELERQGNVLVISH 391 E K RYPG ES + R+ P ++ ++ V++ +H Sbjct: 124 ELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAH 183 Query: 392 QAVMRCLLAYFLDKGADELPYLRCP 416 +R L+ Y + +E+ L P Sbjct: 184 GNSLRALVKYLDNMSEEEILELNIP 208 >4PZA-A nrPDB Length = 223 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 17/144 (11%) Query: 247 VQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQL 304 ++ R + + RHG++++N+ ++ G D+ LS G+ A A + L +++ L + +S L Sbjct: 1 MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQ--PLLIVSSDL 58 Query: 305 KRTIQTAESLGVPYEQWKILNEIDA-------GVCEEMTYAEIEKRYP-EEFALRDQEKY 356 +R TA LG E+ ++ +D G + +T+A+I+ P A R E Sbjct: 59 RRAYDTAVKLG---ERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWR--EDA 113 Query: 357 LYRYPGGESYQDLVQRLEPVIMEL 380 + GGES D+ R P++ EL Sbjct: 114 TWAPHGGESRVDVAARSRPLVAEL 137 >5VVE-A nrPDB Length = 258 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 60/206 (29%), Positives = 87/206 (42%), Gaps = 43/206 (20%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRG-KQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 + L RHGESE+N K G D GLS G K+ +A L+E DL +TS LKR I Sbjct: 13 LVLIRHGESEWNKENKFTGWYDCGLSETGLKEAKEAGEILLKEGYEFDL-CYTSFLKRAI 71 Query: 309 QT----AESLGVPY----EQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLY-- 358 +T E++ Y + W+ LNE G + + + +++ EE + Y Sbjct: 72 KTLWIALETMDAMYLPVVKHWR-LNERHYGALQGLNKTQTAEKHGEEQVKIWRRSYDIPP 130 Query: 359 --------RYPGGE-SYQDLVQRLEP------------------VIMELERQGN-VLVIS 390 RYPG E YQ L Q P VI ++G VL+ + Sbjct: 131 PALEVTDERYPGHERKYQGLTQEELPKTESLKLTVDRVLPYWNDVIAPSVKEGKRVLIAA 190 Query: 391 HQAVMRCLLAYFLDKGADELPYLRCP 416 H +R L+ Y + +E+ L P Sbjct: 191 HGNSLRALVKYLDNISEEEIVELNIP 216 >4ODI-A nrPDB Length = 281 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 57/211 (27%), Positives = 87/211 (41%), Gaps = 46/211 (21%) Query: 241 YLMNIHVQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLK 298 + N+ T+ L RHGES +N + G D LS G+Q A K L+E+ Sbjct: 10 FFGNMAKAKYTLVLIRHGESTWNKENRFTGWTDVPLSPVGEQEAVEAAKALKEKGFEFDV 69 Query: 299 VWTSQLKRTIQTAESL-------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE---- 347 +TS L+R + T ++ +P + LNE G + + AE ++ +E Sbjct: 70 AYTSVLQRAVVTCWTVLKGTDMCHIPVKSSWRLNERHYGALQGLNKAETAAKHGDEQVKI 129 Query: 348 ------FALRDQEKYLYRYPGG---------------ESYQDLVQR--------LEPVIM 378 EK R+PG E +D V+R + P IM Sbjct: 130 WRRSYDIPPPPLEKSDKRWPGNDAVYKMVPNEALPLTECLKDTVERVLPFWFDHIAPSIM 189 Query: 379 ELERQGNVLVISHQAVMRCLLAYFLDKGADE 409 E +R VLV +H +R L+ + LDK +DE Sbjct: 190 EGKR---VLVAAHGNSLRGLVKH-LDKMSDE 216 >1FZT-A nrPDB Length = 211 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 14/171 (8%) Query: 243 MNIHVQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVW 300 M P + L RHGESE+N L G D LS G + A+ + L+ + + Sbjct: 1 MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAF 60 Query: 301 TSQLKRTIQTA----ESLGVP-YEQWKI--LNEIDAGVCEEMTYAEIEKRYPEEFALRDQ 353 TS L+R +T E +G P E K LNE G + + + K++ E + Sbjct: 61 TSALQRAQKTCQIILEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKWGAEQVQIWR 120 Query: 354 EKYLYRYPGGESYQDLVQRLEP-----VIMELERQGNVLVISHQAVMRCLL 399 Y P GES +D +R+ P ++ + + VL+ +H +R L+ Sbjct: 121 RSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALI 171 >3D8H-A nrPDB Length = 267 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 103/242 (42%), Gaps = 55/242 (22%) Query: 252 IYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQAL---RKFLEEQEITDLKVWTSQLKRTI 308 + L RHGESE+N + G + +S+ + ++A+ R LE+ D+ V+TS LKR I Sbjct: 23 LTLIRHGESEWNKENRFTGWTDVSLSEQGVSEAIEAGRMLLEKGFKFDV-VYTSVLKRAI 81 Query: 309 QTAES-------LGVP-YEQWKILNEIDAGVCEEMTYAEIEKRYPEE--------FALRD 352 T + + P W+ LNE G + + +E ++ E+ F + Sbjct: 82 MTTWTVLKELGNINCPIINHWR-LNERHYGALQGLNKSETASKFGEDQVKIWRRSFDVPP 140 Query: 353 Q--EKYLYRYPGG---------------ESYQDLVQRLEP----VIMELERQG-NVLVIS 390 EK R+PG E +D V+R++P VI G +VLV + Sbjct: 141 PVLEKSDPRWPGNELIYKGICPSCLPTTECLKDTVERVKPYFEDVIAPSIMSGKSVLVSA 200 Query: 391 HQAVMRCLLAYFLDKGADE------LPYLRCP----LHTIFKLTPVAYGCKVETIKLNVE 440 H +R LL Y L+ E +P CP L K+T Y E +K +E Sbjct: 201 HGNSLRALL-YLLEGMTPEQILEVNIP-TACPLVLELDDYLKVTKKYYLISEEELKAKME 258 Query: 441 AV 442 AV Sbjct: 259 AV 260 >3GW8-A nrPDB Length = 257 Score = 37.4 bits (85), Expect = 0.016, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 41/191 (21%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHGES +N + G D L+ +G + A+ + L+E T +TS LKR I+ Sbjct: 12 LVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIR 71 Query: 310 T-------AESLGVP-YEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLY--- 358 T + + VP W+ LNE G + AE +Y +E L + Y Sbjct: 72 TLWHVQDQMDLMYVPVVHSWR-LNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPP 130 Query: 359 --------------RY--------PGGESYQDLVQRLEPVIME-----LERQGNVLVISH 391 RY P E +D V R+ P+ E ++ VL+ +H Sbjct: 131 ALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAAH 190 Query: 392 QAVMRCLLAYF 402 +R L+ Y Sbjct: 191 GNSLRALIKYL 201 >4C0E-A nrPDB Length = 528 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Query: 19 PNLRMSEKKCSWASYMTNSPTLIVMIGLP-ARGKTYVSKKLTRYLNWIGVPTKVFNLGVY 77 PNL + C+WA +++ L V++GLP +G +K L ++L +G K F + Sbjct: 185 PNL-LPGFACAWAGLVSHRAFLPVILGLPDEKGWAPFTKLLEQFLGCVGELVKTFTVSSL 243 Query: 78 RRE 80 +E Sbjct: 244 GKE 246 >5L3R-A nrPDB Length = 301 Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 30/62 (48%) Query: 21 LRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRE 80 +++ + S + + PT+I++ GL GKT V KL YL G + VYR Sbjct: 89 VKLMGGEVSELQFAKSGPTVILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYRPA 148 Query: 81 AV 82 A+ Sbjct: 149 AI 150 >4XRP-A nrPDB Length = 312 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 21/119 (17%) Query: 38 PTLIVMIGLPARGKTYVSKKLTRYL-NWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNE 96 P L++++G P GK+ ++ R NW+ V F L + + + E Sbjct: 11 PKLLILVGAPGSGKSTFARYFIRTEDNWVRVNRDDFRLMQFGDSLMSPFY---------E 61 Query: 97 EAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTT-RERRDMILNFAEQN--SFKVF 152 E + + +++AL +N + DATN++ R +DM+ + E SFKVF Sbjct: 62 ERITKMVEASVIAL--------LKNRTNVIIDATNSSLRSLQDMVHTYTEYADISFKVF 112 >3LVQ-E nrPDB Length = 497 Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 19/154 (12%) Query: 34 MTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRH 93 ++N I+M+GL A GKT + KL + +PT FN+ E V +YK+ F Sbjct: 318 LSNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETV-TYKNVKFNVW 371 Query: 94 DNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTR---ERRDM--ILNFAEQNS 148 D KIR + Y T G I V D + R R+++ I+N E Sbjct: 372 DVGGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 423 Query: 149 FKVFFVESVCDDPDVIAANILEVKVSSPDYPERN 182 + + D PD + + ++ K+ +RN Sbjct: 424 AIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 457 >5Y64-B nrPDB Length = 262 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 19/83 (22%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRG----KQFAQALRKFLEEQEITDLKVWTSQLK 305 + L RHGES +NL + G D+ LS G K+ QALR E +I +TS K Sbjct: 6 LVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDI----CFTSVQK 61 Query: 306 RTIQTAESLGVPYEQWKILNEID 328 R I+T W +L+ ID Sbjct: 62 RAIRTL---------WTVLDAID 75 >5XBP-A nrPDB Length = 446 Score = 32.7 bits (73), Expect = 0.39, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 292 QEITDLK--VWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFA 349 +EI D++ ++ S L TI S +K+ N ID E TYA +EK PE+ Sbjct: 280 KEIGDVRARIYRSHLNGTIFPNNSFLTGSAAFKVWNPIDENTTEVWTYAFVEKDMPEDLK 339 Query: 350 LR 351 R Sbjct: 340 RR 341 >1EG9-A nrPDB Length = 449 Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Query: 292 QEITDLK--VWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFA 349 +EI D++ ++ S L T+ S+ +K+ N IDA E TYA +EK PE+ Sbjct: 282 KEIGDVRARIYRSHLNCTVFPNNSMLTCSGVFKVWNPIDANTTEVWTYAIVEKDMPEDLK 341 Query: 350 LR 351 R Sbjct: 342 RR 343 >4EMB-A nrPDB Length = 274 Score = 32.3 bits (72), Expect = 0.51, Method: Compositional matrix adjust. Identities = 48/205 (23%), Positives = 81/205 (39%), Gaps = 41/205 (20%) Query: 252 IYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRK-FLEEQEITDLKV-WTSQLKRTIQ 309 + L RHGESE+N G + + + K +A+ L +QE + ++S L R Sbjct: 30 LVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRAND 89 Query: 310 T----AESLGVPY----EQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKY----- 356 T LG Y + W+ LNE G + + +E +Y E+ L + Y Sbjct: 90 TLNIILRELGQSYISVKKTWR-LNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPPM 148 Query: 357 --------------LYRY------PGGESYQDLVQRLEP-----VIMELERQGNVLVISH 391 Y++ P E +D V R+ P + E+ V+V +H Sbjct: 149 SLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGKKVIVAAH 208 Query: 392 QAVMRCLLAYFLDKGADELPYLRCP 416 +R L+ YF + +++ L P Sbjct: 209 GNSLRALVKYFDNLSEEDVLKLNIP 233 >3UHP-A nrPDB Length = 274 Score = 32.0 bits (71), Expect = 0.57, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 11/77 (14%) Query: 232 DYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLG----KIGGDSGLSVRGKQFAQALRK 287 D++QS + YY NI I C H F LLG K GD + A+ + Sbjct: 181 DFLQSAMEYYFKNITTPDALILACTH----FPLLGRSLSKYFGDKTKLIHS---GDAIVE 233 Query: 288 FLEEQEITDLKVWTSQL 304 FL+E+E DLK ++L Sbjct: 234 FLKERENIDLKNHKAKL 250 >3DM5-A nrPDB Length = 443 Score = 32.0 bits (71), Expect = 0.65, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 46/114 (40%), Gaps = 15/114 (13%) Query: 34 MTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIG-----VPTKVFNLGVYR--REAVKSYK 86 + PT+++M+G+ GKT KL RY G V + + G Y R+ + Y Sbjct: 96 IKEKPTILLMVGIQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPGAYHQLRQLLDRYH 155 Query: 87 SYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMI 140 F ++A+K+ K+ Y + I + D +E + +I Sbjct: 156 IEVFGNPQEKDAIKLAKEGV--------DYFKSKGVDIIIVDTAGRHKEDKALI 201 >2A5F-A nrPDB Length = 175 Score = 32.0 bits (71), Expect = 0.68, Method: Compositional matrix adjust. Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 19/152 (12%) Query: 36 NSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDN 95 N I+M+GL A GKT + KL + +PT FN+ E V +YK+ F D Sbjct: 11 NKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETV-TYKNVKFNVWDV 64 Query: 96 EEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTR---ERRDM--ILNFAEQNSFK 150 KIR + Y T G I V D + R R+++ I+N E Sbjct: 65 GGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 116 Query: 151 VFFVESVCDDPDVIAANILEVKVSSPDYPERN 182 + + D PD + + ++ K+ +RN Sbjct: 117 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 148 >3HJG-A nrPDB Length = 213 Score = 31.6 bits (70), Expect = 0.80, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 18/162 (11%) Query: 252 IYLCRHGESEFNLLGKIGGDSGLSVR---GKQFAQALR-KFLEEQEITDLKVWTSQLKRT 307 IYL RHG+ + + G + L V+ +Q A A + K + I +S L R Sbjct: 8 IYLMRHGK--VDAAPGLHGQTDLKVKEAEQQQIAMAWKTKGYDVAGII-----SSPLSRC 60 Query: 308 IQTAESLG----VPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGG 363 A+ L +P L E+D G + M + + + + + A Q + P Sbjct: 61 HDLAQILAEQQLLPMTTEDDLQEMDFGDFDGMPFDLLTEHWKKLDAFW-QSPAHHSLPNA 119 Query: 364 ESYQDLVQRLEPVIMEL--ERQGNVLVISHQAVMRCLLAYFL 403 ES QR+ ++ + N+L+++H V+R +LA+ L Sbjct: 120 ESLSTFSQRVSRAWSQIINDINDNLLIVTHGGVIRIILAHVL 161 >6BBQ-A nrPDB Length = 520 Score = 31.6 bits (70), Expect = 0.89, Method: Compositional matrix adjust. Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 20/167 (11%) Query: 22 RMSEKKCSWASYM-TNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRE 80 R++ KK S + N I+M+GL A GKT + KL + +PT FN+ E Sbjct: 342 RIANKKGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----E 396 Query: 81 AVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDAT-----NTTRE 135 V +YK+ F D KIR + Y T G I V D + R+ Sbjct: 397 TV-TYKNVKFNVWDVGGLDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQ 447 Query: 136 RRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERN 182 I+N E + + D PD + + ++ K+ +RN Sbjct: 448 ELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 494 >4C5U-A nrPDB Length = 707 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 4/53 (7%) Query: 382 RQGNVLVISHQAVMRCLLAYFLDKGA----DELPYLRCPLHTIFKLTPVAYGC 430 R+ N L ++++RCLLA KG DELP + +L YGC Sbjct: 112 RRTNRLSELQESLIRCLLAGVFTKGCAPSVDELPATATRSAMLLRLNSFTYGC 164 >2RHQ-B nrPDB Length = 795 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 30/51 (58%) Query: 329 AGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIME 379 AG+ + +TY+ + K + ++FAL+++ P E++ L Q L P ++E Sbjct: 509 AGLNQAITYSLVSKDHAKDFALQERPTISLLMPMSEAHATLRQSLLPHLIE 559 >2YVU-A nrPDB Length = 186 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 12/110 (10%) Query: 40 LIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAM 99 ++ + GLP GKT ++ +L L G +V + G + R V + EE + Sbjct: 15 VVWLTGLPGSGKTTIATRLADLLQKEGYRVEVLD-GDWARTTVSEGAGF-----TREERL 68 Query: 100 KIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSF 149 + K+ A + A L NG I + + ++ R+M+ E+ Sbjct: 69 RHLKRIAWI------ARLLARNGVIVICSFVSPYKQARNMVRRIVEEEGI 112 >2BMQ-A nrPDB Length = 447 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 292 QEITDLK--VWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFA 349 +EI D++ ++ S L TI S +++ N ID E TYA +EK PE+ Sbjct: 280 KEIGDVRARIYRSFLNGTIFPNNSFLTGSAAFRVWNPIDENTTEVWTYAFVEKDMPEDLK 339 Query: 350 LR 351 R Sbjct: 340 RR 341 >4CMR-A nrPDB Length = 597 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 9/81 (11%) Query: 371 QRLEPVIMEL---ERQGN----VLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKL 423 +RL PV +E+ E +G ++ +++ V L LD+GA + + L+ + K Sbjct: 33 ERLSPVALEIREEEVKGRNWTRAMIKAYEYVDETLR--MLDEGAVSVDFEPFTLYMVLKY 90 Query: 424 TPVAYGCKVETIKLNVEAVNT 444 P YG VET++ +VE T Sbjct: 91 KPKIYGEIVETLETHVEPTVT 111 >2V3C-C nrPDB Length = 432 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 24/47 (51%) Query: 40 LIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYK 86 +I+++G+ GKT + KL RY+ G+ + YR A + K Sbjct: 101 VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYRPAAYEQLK 147 >2JGP-A nrPDB Length = 520 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 8/53 (15%) Query: 91 FRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDAT-NTTRERRDMILN 142 F++ EE M + +C L ++T+E GQ A FD T + T ER +M + Sbjct: 434 FQNSTEEVMTL-PECTLAP------FMTDETGQHAKFDLTFSATEEREEMTIG 479 >3CVR-A nrPDB Length = 571 Score = 28.1 bits (61), Expect = 9.1, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 21/86 (24%) Query: 270 GDSGLSVRGKQFAQALRKFLEEQEITD----LKVWTSQLKRTIQTAESLGVPYEQWKILN 325 G SG++ + A+A+ + EE E TD W + LKRT ++W Sbjct: 452 GVSGVTANDLRTAEAMVRSREENEFTDWFSLWGPWHAVLKRT---------EADRW---- 498 Query: 326 EIDAGVCEEMTYAEIEKRYPEEFALR 351 + EE Y +E YP+ A R Sbjct: 499 ----ALAEEQKYEMLENEYPQRVADR 520 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5HTK-A nrPDB 894 0.0 5HR5-A nrPDB 877 0.0 2DWP-A nrPDB 768 0.0 4D4L-A nrPDB 734 0.0 2BIF-A nrPDB 713 0.0 1K6M-A nrPDB 693 0.0 1C7Z-A nrPDB 307 9e-84 4EO9-A nrPDB 208 5e-54 1RII-A nrPDB 207 9e-54 4ODI-A nrPDB 202 2e-52 3KKK-A nrPDB 199 3e-51 1E58-A nrPDB 196 2e-50 1FZT-A nrPDB 190 1e-48 5VVE-A nrPDB 189 2e-48 3PGM-A nrPDB 187 7e-48 5PGM-D nrPDB 187 1e-47 4IJ6-A nrPDB 166 2e-41 6NRU-A nrPDB 153 1e-37 4PZA-A nrPDB 134 9e-32 Sequences not found previously or not previously below threshold: 3GW8-A nrPDB 184 6e-47 5Y64-B nrPDB 175 3e-44 4EMB-A nrPDB 175 5e-44 3D8H-A nrPDB 172 4e-43 5UM0-A nrPDB 169 2e-42 3NFY-A nrPDB 153 2e-37 3E9D-A nrPDB 81 9e-16 3HJG-A nrPDB 73 3e-13 3LG2-A nrPDB 68 1e-11 3DCY-A nrPDB 68 1e-11 3R7A-A nrPDB 64 2e-10 2YN2-A nrPDB 58 1e-08 3F2I-A nrPDB 48 1e-05 3DM5-A nrPDB 40 0.003 3LVQ-E nrPDB 39 0.006 6BBQ-A nrPDB 37 0.017 2A5F-A nrPDB 37 0.020 4XRP-A nrPDB 32 0.47 2V3C-C nrPDB 32 0.56 5L3R-A nrPDB 32 0.61 2YVU-A nrPDB 32 0.65 3B9O-A nrPDB 31 1.1 6FAE-B nrPDB 31 1.4 3O47-A nrPDB 31 1.7 6DFF-C nrPDB 30 1.8 1J2J-A nrPDB 30 1.8 3AQ4-A nrPDB 30 2.0 4YLG-A nrPDB 30 2.4 1LFP-A nrPDB 30 2.5 4C0E-A nrPDB 30 2.9 2IYT-A nrPDB 30 3.2 4CMR-A nrPDB 30 3.3 1WDT-A nrPDB 29 5.0 5HX2-D nrPDB 28 7.8 >5HTK-A nrPDB Length = 505 Score = 894 bits (2311), Expect = 0.0, Method: Composition-based stats. Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 1 MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTR 60 MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTR Sbjct: 1 MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTR 60 Query: 61 YLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEE 120 YLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEE Sbjct: 61 YLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEE 120 Query: 121 NGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPE 180 NGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPE Sbjct: 121 NGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPE 180 Query: 181 RNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVY 240 RNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVY Sbjct: 181 RNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVY 240 Query: 241 YLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVW 300 YLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVW Sbjct: 241 YLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVW 300 Query: 301 TSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 TSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY Sbjct: 301 TSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 Query: 361 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTI 420 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTI Sbjct: 361 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTI 420 Query: 421 FKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR 480 FKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR Sbjct: 421 FKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR 480 Query: 481 NYSVGSRPLKPLSPLRAQDMQEGAD 505 NYSVGSRPLKPLSPLRAQDMQEGAD Sbjct: 481 NYSVGSRPLKPLSPLRAQDMQEGAD 505 >5HR5-A nrPDB Length = 531 Score = 877 bits (2265), Expect = 0.0, Method: Composition-based stats. Identities = 480/507 (94%), Positives = 498/507 (98%), Gaps = 3/507 (0%) Query: 1 MSG--ASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKL 58 MSG ASSSEQNNNSYETK +LR+SEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKL Sbjct: 1 MSGNPASSSEQNNNSYETKA-SLRISEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKL 59 Query: 59 TRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLT 118 TRYLNWIGVPTKVFNLGVYRR+AVKSYKSYDFFRHDNEEAMKIRKQCALVAL+DVKAYLT Sbjct: 60 TRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLT 119 Query: 119 EENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDY 178 EE+GQIAVFDATNTTRERRD+ILNFAE+NSFKVFFVESVCDDPDVIAANILEVKVSSPDY Sbjct: 120 EESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDY 179 Query: 179 PERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKI 238 PERNRENVM+DFLKRIECYKVTY+PLDPD++DKDLSFIKVINVGQRFLVN+VQDYIQSKI Sbjct: 180 PERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKI 239 Query: 239 VYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLK 298 VYYLMNIHV PRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEI DLK Sbjct: 240 VYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLK 299 Query: 299 VWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLY 358 VWTSQLKRTIQTAESLGV YEQWKILNEIDAGVCEEMTYAEI+++YP+EFALRD+EKYLY Sbjct: 300 VWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLY 359 Query: 359 RYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH 418 RYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH Sbjct: 360 RYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH 419 Query: 419 TIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRR 478 TIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRR Sbjct: 420 TIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRR 479 Query: 479 PRNYSVGSRPLKPLSPLRAQDMQEGAD 505 PRNYSVGSRPL+PLSPLRA D QEGAD Sbjct: 480 PRNYSVGSRPLQPLSPLRALDTQEGAD 506 >2DWP-A nrPDB Length = 520 Score = 768 bits (1982), Expect = 0.0, Method: Composition-based stats. Identities = 334/452 (73%), Positives = 390/452 (86%), Gaps = 2/452 (0%) Query: 29 SWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSY 88 S +TNSPT+IVM+GLPARGKTY+SKKLTRYLNWIGVPTKVFN+G YRREAVK Y SY Sbjct: 26 SCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSY 85 Query: 89 DFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNS 148 +FFR DNEEAMK+RKQCAL AL DVK+YL +E GQIAVFDATNTTRERR MIL+FA++N Sbjct: 86 NFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKEND 145 Query: 149 FKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDN 208 FK FF+ESVCDDP V+A+NI+EVK+SSPDY + N M+DF+KRI CY+ +Y+PLDPD Sbjct: 146 FKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDK 205 Query: 209 YDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKI 268 D+DLS IKVI+VG+RFLVNRVQD+IQS+IVYYLMNIHVQPRTIYLCRHGE+E NL G+I Sbjct: 206 CDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRI 265 Query: 269 GGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEID 328 GGDSGLS RGK+FA AL KF+EEQ + DL+VWTSQLK TIQTAE+L +PYEQWK LNEID Sbjct: 266 GGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEID 325 Query: 329 AGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLV 388 AGVCEE+TY EI YPEE+ALR+Q+KY YRYP GESYQDLVQRLEPVIMELERQ NVLV Sbjct: 326 AGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLV 385 Query: 389 ISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDK 448 I HQAV+RCLLAYFLDK A+E+PYL+CPLHT+ KLTPVAYGC+VE+I LNVE+V THR++ Sbjct: 386 ICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRER 445 Query: 449 PTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPR 480 + + K P+ MRRNS TPL+S ++PR Sbjct: 446 -SEDAKKGPNPL-MRRNSVTPLASPEPTKKPR 475 >4D4L-A nrPDB Length = 449 Score = 734 bits (1895), Expect = 0.0, Method: Composition-based stats. Identities = 321/423 (75%), Positives = 372/423 (87%) Query: 29 SWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSY 88 S +TNSPT+IVM+GLPARGKTY+SKKLTRYLNWIGVPTKVFN+G YRREAVK Y SY Sbjct: 26 SCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSY 85 Query: 89 DFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNS 148 +FFR DNEEAMK+RKQCAL AL DVK+YL +E GQIAVFDATNTTRERR MIL+FA++N Sbjct: 86 NFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKEND 145 Query: 149 FKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDN 208 FK FF+ESVCDDP V+A+NI+EVK+SSPDY + N M+DF+KRI CY+ +Y+PLDPD Sbjct: 146 FKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDK 205 Query: 209 YDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKI 268 D+DLS IKVI+VG+RFLVNRVQD+IQS+IVYYLMNIHVQPRTIYLCRHGE+E NL G+I Sbjct: 206 CDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRI 265 Query: 269 GGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEID 328 GGDSGLS RGK+FA AL KF+EEQ + DL+VWTSQLK TIQTAE+L +PYEQWK LNEID Sbjct: 266 GGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEID 325 Query: 329 AGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLV 388 AGVCEE+TY EI YPEE+ALR+Q+KY YRYP GESYQDLVQRLEPVIMELERQ NVLV Sbjct: 326 AGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLV 385 Query: 389 ISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDK 448 I HQAV+RCLLAYFLDK A+E+PYL+CPLHT+ KLTPVAYGC+VE+I LNVE+V THR++ Sbjct: 386 ICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRER 445 Query: 449 PTN 451 + Sbjct: 446 SED 448 >2BIF-A nrPDB Length = 469 Score = 713 bits (1840), Expect = 0.0, Method: Composition-based stats. Identities = 306/438 (69%), Positives = 366/438 (83%), Gaps = 5/438 (1%) Query: 14 YETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFN 73 Y P L S++ MTN PTLIVM+GLPARGKTY+SKKLTRYLN+IGVPT+ FN Sbjct: 19 YSNGRPALHASQRGVC----MTNCPTLIVMVGLPARGKTYISKKLTRYLNFIGVPTREFN 74 Query: 74 LGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTT 133 +G YRR+ VK+YKS++FF DNEE +KIRKQCAL AL DV+ +L+EE G +AVFDATNTT Sbjct: 75 VGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEGGHVAVFDATNTT 134 Query: 134 RERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKR 193 RERR MI NF EQN +K FFVES+C DP+VIAANI++VK+ SPDY R+ + EDF++R Sbjct: 135 RERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRR 194 Query: 194 IECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIY 253 IECY+ +Y LD + D+DLS+IK+++VGQ ++VNRV D+IQS+IVYYLMNIHV PR+IY Sbjct: 195 IECYENSYESLDEEQ-DRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIY 253 Query: 254 LCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAES 313 LCR GESE NL G+IGGD GLS RG++F++ L +F+ +Q I DLKV+TSQ+KRTIQTAE+ Sbjct: 254 LCRAGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVFTSQMKRTIQTAEA 313 Query: 314 LGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRL 373 L VPYEQ+K+LNEIDAGVCEEMTY EI+ YP EFALRDQ+KY YRYP GESY+DLVQRL Sbjct: 314 LSVPYEQFKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRL 373 Query: 374 EPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVE 433 EPVIMELERQ NVLVI HQAVMRCLLAYFLDK A+ELPYL+CPLHT+ KLTPVAYGCKVE Sbjct: 374 EPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLKLTPVAYGCKVE 433 Query: 434 TIKLNVEAVNTHRDKPTN 451 +I LNV AVNTHRD+P N Sbjct: 434 SIFLNVAAVNTHRDRPQN 451 >1K6M-A nrPDB Length = 432 Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats. Identities = 305/416 (73%), Positives = 364/416 (87%), Gaps = 2/416 (0%) Query: 36 NSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDN 95 NSPT+++M+GLPARGKTY+S KLTRYLN+IG PTKVFNLG YRREAV SYK+Y+FF DN Sbjct: 1 NSPTMVIMVGLPARGKTYISTKLTRYLNFIGTPTKVFNLGQYRREAV-SYKNYEFFLPDN 59 Query: 96 EEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVE 155 EA++IRKQCAL AL+DV YL+ E G +AVFDATNTTRERR +IL FA+++ +KVFF+E Sbjct: 60 MEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIE 119 Query: 156 SVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSF 215 S+C+DP +IA NI +VK+ SPDY + +RE V+EDFLKRIECY+V Y+PLD + D LS+ Sbjct: 120 SICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLD-EELDSHLSY 178 Query: 216 IKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLS 275 IK+ +VG R++VNRVQD+IQS+ VYYLMNIHV PR+IYLCRHGESE N+ G+IGGDSGLS Sbjct: 179 IKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLS 238 Query: 276 VRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEM 335 VRGKQ+A AL F++ Q I+ LKV+TS++KRTIQTAE+LGVPYEQ+K LNEIDAGVCEEM Sbjct: 239 VRGKQYAYALANFIQSQGISSLKVFTSRMKRTIQTAEALGVPYEQFKALNEIDAGVCEEM 298 Query: 336 TYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVM 395 TY EI++ YPEEFALRDQ+KY YRYP GESY+DLVQRLEPVIMELERQ NVLVI HQAVM Sbjct: 299 TYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVM 358 Query: 396 RCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTN 451 RCLLAYFLDK ++ELPYL+CPLHT+ KLTPVAYGCKVE+I LNVEAVNTHR+KP N Sbjct: 359 RCLLAYFLDKSSEELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPEN 414 >1C7Z-A nrPDB Length = 191 Score = 307 bits (786), Expect = 9e-84, Method: Composition-based stats. Identities = 153/190 (80%), Positives = 169/190 (88%) Query: 250 RTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 R+IYLCRHGESE NL G+IGGDSGLS RGKQ+A AL F+ Q I+ LKVWTS +KRTIQ Sbjct: 2 RSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQGISSLKVWTSHMKRTIQ 61 Query: 310 TAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDL 369 TAE+LGVPYEQWK LNEIDAGVCEEMTY EI++ YPEEFALRDQ+KY YRYP GESY+DL Sbjct: 62 TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL 121 Query: 370 VQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYG 429 VQRLEPVIMELERQ NVLVI HQAVMRCLLAYFLDK +DELPYL+CPLHT+ KLTPVAYG Sbjct: 122 VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG 181 Query: 430 CKVETIKLNV 439 C+VE+I LNV Sbjct: 182 CRVESIYLNV 191 >4EO9-A nrPDB Length = 268 Score = 208 bits (529), Expect = 5e-54, Method: Composition-based stats. Identities = 60/234 (25%), Positives = 93/234 (39%), Gaps = 47/234 (20%) Query: 251 TIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 T+ L RHGES++N G D GL+ +G+ A + L E + ++TS L+R I Sbjct: 29 TLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLRRAI 88 Query: 309 -------QTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYP 361 TA+ L +P + LNE G + + A + RY EE + + Y P Sbjct: 89 TTAHLALDTADWLWIPVRRSWRLNERHYGALQGLDKAVTKARYGEERFMAWRRSYDTPPP 148 Query: 362 -------------------GG----ESYQDLVQRLEP-----VIMELERQGNVLVISHQA 393 GG E D+V R P ++ +L VL+++H Sbjct: 149 PIEKGSEFSQDADPRYTDIGGGPLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGN 208 Query: 394 VMRCLLAYFLDKGADELPYLRCPLHTIFK------LTPVAYGCKVETIKLNVEA 441 +R L+ + + DE+ L P + L PV G L+ EA Sbjct: 209 SLRALVKHLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPG----GTYLDPEA 258 >1RII-A nrPDB Length = 265 Score = 207 bits (527), Expect = 9e-54, Method: Composition-based stats. Identities = 53/209 (25%), Positives = 87/209 (41%), Gaps = 37/209 (17%) Query: 251 TIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 ++ L RHGES++N L G D GL+ +G+ A + + E ++ ++TS L+R I Sbjct: 6 SLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAI 65 Query: 309 QTA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYP 361 TA + L +P + LNE G + + AE + RY EE + + Y P Sbjct: 66 TTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPP 125 Query: 362 -------------------GG----ESYQDLVQRLEP-----VIMELERQGNVLVISHQA 393 GG E D+V R P ++ +L VL+++H Sbjct: 126 PIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGN 185 Query: 394 VMRCLLAYFLDKGADELPYLRCPLHTIFK 422 +R L+ + DE+ L P + Sbjct: 186 SLRALVKHLDQMSDDEIVGLNIPTGIPLR 214 >4ODI-A nrPDB Length = 281 Score = 202 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 49/220 (22%), Positives = 81/220 (36%), Gaps = 39/220 (17%) Query: 241 YLMNIHVQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLK 298 + N+ T+ L RHGES +N + G D LS G+Q A K L+E+ Sbjct: 10 FFGNMAKAKYTLVLIRHGESTWNKENRFTGWTDVPLSPVGEQEAVEAAKALKEKGFEFDV 69 Query: 299 VWTSQLKRTIQTAESL-------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALR 351 +TS L+R + T ++ +P + LNE G + + AE ++ +E Sbjct: 70 AYTSVLQRAVVTCWTVLKGTDMCHIPVKSSWRLNERHYGALQGLNKAETAAKHGDEQVKI 129 Query: 352 DQEKYLY----------RYPGG---------------ESYQDLVQRLEPV-----IMELE 381 + Y R+PG E +D V+R+ P + Sbjct: 130 WRRSYDIPPPPLEKSDKRWPGNDAVYKMVPNEALPLTECLKDTVERVLPFWFDHIAPSIM 189 Query: 382 RQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIF 421 VLV +H +R L+ + + + L P Sbjct: 190 EGKRVLVAAHGNSLRGLVKHLDKMSDEAVLELNIPTGVPL 229 >3KKK-A nrPDB Length = 258 Score = 199 bits (505), Expect = 3e-51, Method: Composition-based stats. Identities = 54/214 (25%), Positives = 85/214 (39%), Gaps = 39/214 (18%) Query: 247 VQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQL 304 + T+ L RHGES +N K G D LS +G++ A A K+L+E+ V+TS L Sbjct: 9 MTTYTLVLLRHGESTWNKENKFTGWTDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSVL 68 Query: 305 KRTI-------QTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYL 357 KR I +TA+ L VP + LNE G + + +E K+Y EE + Y Sbjct: 69 KRAICTAWNVLKTADLLHVPVVKTWRLNERHCGSLQGLNKSETAKKYGEEQVKIWRRSYD 128 Query: 358 YRYPG-------------------------GESYQDLVQRLEPV-----IMELERQGNVL 387 P E +D V+R+ P ++ V+ Sbjct: 129 IPPPKLDKEDNRWPGHNVVYKNVPKDALPFTECLKDTVERVLPFWFDHIAPDILANKKVM 188 Query: 388 VISHQAVMRCLLAYFLDKGADELPYLRCPLHTIF 421 V +H +R L+ + + ++ L P Sbjct: 189 VAAHGNSLRGLVKHLDNLSEADVLELNIPTGVPL 222 >1E58-A nrPDB Length = 249 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 39/209 (18%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHGES++N + G D LS +G A+A K L+E+ + +TS LKR I Sbjct: 5 LVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIH 64 Query: 310 TAESL-------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQE-------- 354 T ++ +P E+ LNE G + + AE ++Y +E + + Sbjct: 65 TLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPE 124 Query: 355 --KYLYRYPGG---------------ESYQDLVQRLEP-----VIMELERQGNVLVISHQ 392 K RYPG ES + R+ P ++ ++ V++ +H Sbjct: 125 LTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHG 184 Query: 393 AVMRCLLAYFLDKGADELPYLRCPLHTIF 421 +R L+ Y + +E+ L P Sbjct: 185 NSLRALVKYLDNMSEEEILELNIPTGVPL 213 >1FZT-A nrPDB Length = 211 Score = 190 bits (483), Expect = 1e-48, Method: Composition-based stats. Identities = 49/215 (22%), Positives = 87/215 (40%), Gaps = 19/215 (8%) Query: 243 MNIHVQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVW 300 M P + L RHGESE+N L G D LS G + A+ + L+ + + Sbjct: 1 MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAF 60 Query: 301 TSQLKRTIQTA----ESLGVP---YEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQ 353 TS L+R +T E +G P + + LNE G + + + K++ E + Sbjct: 61 TSALQRAQKTCQIILEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKWGAEQVQIWR 120 Query: 354 EKYLYRYPGGESYQDLVQRLEP-----VIMELERQGNVLVISHQAVMRCLLAYFLDKGAD 408 Y P GES +D +R+ P ++ + + VL+ +H +R L+ D Sbjct: 121 RSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALIMDLEGLTGD 180 Query: 409 ELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVN 443 ++ P+ Y + ++ E ++ Sbjct: 181 QIVKRELATG-----VPIVYHLDKDGKYVSKELID 210 >5VVE-A nrPDB Length = 258 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 50/211 (23%), Positives = 83/211 (39%), Gaps = 39/211 (18%) Query: 250 RTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT 307 + L RHGESE+N K G D GLS G + A+ + L ++ +TS LKR Sbjct: 11 YKLVLIRHGESEWNKENKFTGWYDCGLSETGLKEAKEAGEILLKEGYEFDLCYTSFLKRA 70 Query: 308 IQTA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLY-- 358 I+T +++ +P + LNE G + + + +++ EE + Y Sbjct: 71 IKTLWIALETMDAMYLPVVKHWRLNERHYGALQGLNKTQTAEKHGEEQVKIWRRSYDIPP 130 Query: 359 --------RYPGG---------------ESYQDLVQRLEP-----VIMELERQGNVLVIS 390 RYPG ES + V R+ P + ++ VL+ + Sbjct: 131 PALEVTDERYPGHERKYQGLTQEELPKTESLKLTVDRVLPYWNDVIAPSVKEGKRVLIAA 190 Query: 391 HQAVMRCLLAYFLDKGADELPYLRCPLHTIF 421 H +R L+ Y + +E+ L P Sbjct: 191 HGNSLRALVKYLDNISEEEIVELNIPTGVPL 221 >3PGM-A nrPDB Length = 244 Score = 187 bits (476), Expect = 7e-48, Method: Composition-based stats. Identities = 55/208 (26%), Positives = 87/208 (41%), Gaps = 39/208 (18%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHG+SE+N G D LS +G+Q A + L+E+ + L +TS+L R IQ Sbjct: 3 LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKGVNVLVDYTSKLSRAIQ 62 Query: 310 TA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE--------------- 347 TA + L +P + LNE G + A+ K++ EE Sbjct: 63 TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAQTLKKFGEEKFNTYRRSFDVPPPP 122 Query: 348 ------FALRDQEKYLY----RYPGGESYQDLVQRLEP----VIMELERQGNVLVISHQA 393 F+ + E+Y Y P ES ++ RL P VI +L ++ +H Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKLV-GKTSMIAAHGN 181 Query: 394 VMRCLLAYFLDKGADELPYLRCPLHTIF 421 +R L+ + ++ L P TI Sbjct: 182 SLRGLVKHLEGISDADIAKLNIPPGTIL 209 >5PGM-D nrPDB Length = 246 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 52/209 (24%), Positives = 86/209 (41%), Gaps = 39/209 (18%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L RHG+SE+N G D LS +G+Q A + L+E+++ ++TS+L R IQ Sbjct: 3 LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQ 62 Query: 310 TA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEE--------------- 347 TA + L +P + LNE G + AE K++ EE Sbjct: 63 TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPP 122 Query: 348 ------FALRDQEKYLY----RYPGGESYQDLVQRLEP-----VIMELERQGNVLVISHQ 392 F+ + E+Y Y P ES ++ RL P + +L V++ +H Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHG 182 Query: 393 AVMRCLLAYFLDKGADELPYLRCPLHTIF 421 +R L+ + ++ L P Sbjct: 183 NSLRGLVKHLEGISDADIAKLNIPTGIPL 211 >3GW8-A nrPDB Length = 257 Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats. Identities = 51/224 (22%), Positives = 81/224 (36%), Gaps = 45/224 (20%) Query: 250 RTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT 307 + L RHGES +N + G D L+ +G + A+ + L+E T +TS LKR Sbjct: 10 YKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRA 69 Query: 308 IQTA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 I+T + + VP LNE G + AE +Y +E L + Y Sbjct: 70 IRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPP 129 Query: 361 PG-------------------------GESYQDLVQRLEP-----VIMELERQGNVLVIS 390 P E +D V R+ P + ++ VL+ + Sbjct: 130 PALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAA 189 Query: 391 HQAVMRCLLAYFLDKGADELPYLRCPLHTIF------KLTPVAY 428 H +R L+ Y ++ L P LTP+ + Sbjct: 190 HGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRH 233 >5Y64-B nrPDB Length = 262 Score = 175 bits (445), Expect = 3e-44, Method: Composition-based stats. Identities = 44/223 (19%), Positives = 79/223 (35%), Gaps = 46/223 (20%) Query: 247 VQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQL 304 + + L RHGES +NL + G D+ LS G + A+ + L + +TS Sbjct: 1 MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ 60 Query: 305 KRTIQTA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYL 357 KR I+T + + +P + LNE G + AE ++ E + Y Sbjct: 61 KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120 Query: 358 Y---------------------------RYPGGESYQDLVQRLEPV-----IMELERQGN 385 + P ES +D + R P + +++ Sbjct: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR 180 Query: 386 VLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAY 428 VL+ +H +R ++ + + + L P P+ Y Sbjct: 181 VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTG-----IPIVY 218 >4EMB-A nrPDB Length = 274 Score = 175 bits (443), Expect = 5e-44, Method: Composition-based stats. Identities = 44/211 (20%), Positives = 75/211 (35%), Gaps = 39/211 (18%) Query: 250 RTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT 307 + L RHGESE+N G D LS +G A L+++ + ++S L R Sbjct: 28 YKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRA 87 Query: 308 IQTAESL-------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 T + + ++ LNE G + + +E +Y E+ L + Y Sbjct: 88 NDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPP 147 Query: 361 -------------------------PGGESYQDLVQRLEP-----VIMELERQGNVLVIS 390 P E +D V R+ P + E+ V+V + Sbjct: 148 MSLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGKKVIVAA 207 Query: 391 HQAVMRCLLAYFLDKGADELPYLRCPLHTIF 421 H +R L+ YF + +++ L P Sbjct: 208 HGNSLRALVKYFDNLSEEDVLKLNIPTGIPL 238 >3D8H-A nrPDB Length = 267 Score = 172 bits (436), Expect = 4e-43, Method: Composition-based stats. Identities = 54/240 (22%), Positives = 87/240 (36%), Gaps = 47/240 (19%) Query: 250 RTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT 307 + L RHGESE+N + G D LS +G A + L E+ V+TS LKR Sbjct: 21 YKLTLIRHGESEWNKENRFTGWTDVSLSEQGVSEAIEAGRMLLEKGFKFDVVYTSVLKRA 80 Query: 308 IQTAESL-------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 I T ++ P LNE G + + +E ++ E+ + + Sbjct: 81 IMTTWTVLKELGNINCPIINHWRLNERHYGALQGLNKSETASKFGEDQVKIWRRSFDVPP 140 Query: 361 -------------------------PGGESYQDLVQRLEP-----VIMELERQGNVLVIS 390 P E +D V+R++P + + +VLV + Sbjct: 141 PVLEKSDPRWPGNELIYKGICPSCLPTTECLKDTVERVKPYFEDVIAPSIMSGKSVLVSA 200 Query: 391 HQAVMRCLLAYFLDKGADELPYLRCP--------LHTIFKLTPVAYGCKVETIKLNVEAV 442 H +R LL +++ + P L K+T Y E +K +EAV Sbjct: 201 HGNSLRALLYLLEGMTPEQILEVNIPTACPLVLELDDYLKVTKKYYLISEEELKAKMEAV 260 >5UM0-A nrPDB Length = 235 Score = 169 bits (429), Expect = 2e-42, Method: Composition-based stats. Identities = 45/209 (21%), Positives = 73/209 (34%), Gaps = 39/209 (18%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + RHG+SE+N G D LS +G A A K L+E +TS L R I+ Sbjct: 11 LVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIK 70 Query: 310 TA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY-- 360 T + L VP + LNE G + + + ++Y +E + Y Sbjct: 71 TCNIVLEESDQLFVPQIKTWRLNERHYGRLQGLDKKQTAEKYGDEQVRIWRRSYDTLPPL 130 Query: 361 -----------------------PGGESYQDLVQRLEPV-----IMELERQGNVLVISHQ 392 P GE+ + ++R+ P + VLV +H Sbjct: 131 LDKDDAFSAHKDRRYAHLPADVVPDGENLKVTLERVLPFWEDQIAPAILSGKRVLVAAHG 190 Query: 393 AVMRCLLAYFLDKGADELPYLRCPLHTIF 421 +R L + +++ L P Sbjct: 191 NSLRALAKHIEGISDEDIMGLEIPTGQPL 219 >4IJ6-A nrPDB Length = 211 Score = 166 bits (421), Expect = 2e-41, Method: Composition-based stats. Identities = 53/178 (29%), Positives = 88/178 (49%), Gaps = 19/178 (10%) Query: 252 IYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQ 309 + L R ESE+N +G+ G D LS RGK+ A+ L + L + + +++S LKRT Sbjct: 4 LILVRAAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHL--DVIYSSPLKRTYL 61 Query: 310 TA----ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGES 365 TA E+ + + + EID G+ M E+ ++YPE+F +E + + GGES Sbjct: 62 TALEIAEAKNLEVIKEDRIIEIDHGMWSGMLVEEVMEKYPEDFRRWVEEPHKVEFQGGES 121 Query: 366 YQDLVQRLEPVIMELERQG---NVLVISHQAVMRCL--------LAYFLDKGADELPY 412 + R++ + E+ ++ V+V+SH MR + L+ F G D Y Sbjct: 122 LASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWSFGCDNASY 179 >6NRU-A nrPDB Length = 206 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 50/182 (27%), Positives = 83/182 (45%), Gaps = 27/182 (14%) Query: 251 TIYLCRHGESEFNLLGKIGGD--SGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 ++L RHGE++ N+ G G + L+ RG + AQ L L++ ++ V S+L+R Sbjct: 5 RLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDD--VSFDLVLCSELERAQ 62 Query: 309 QTAESL----GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKY-------L 357 TA + +P LNE M + + E R+ + D E Y Sbjct: 63 HTARLVLSDRQLPVHIIPELNE--------MFFGDWEMRHHRDLMQEDAENYSAWCNDWQ 114 Query: 358 YRYP-GGESYQDLVQRLEPVIMEL---ERQGNVLVISHQAVMRCLLAYFLDKGADELPYL 413 + P GE +Q QR+E I L + N+L++SHQ V+ L+A + A+ + + Sbjct: 115 HAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARLIGMPAESMWHF 174 Query: 414 RC 415 R Sbjct: 175 RV 176 >3NFY-A nrPDB Length = 267 Score = 153 bits (387), Expect = 2e-37, Method: Composition-based stats. Identities = 44/215 (20%), Positives = 75/215 (34%), Gaps = 43/215 (20%) Query: 247 VQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQL 304 + + + RHGE +N + D L+ G + A+ K L+ V+TS L Sbjct: 1 MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL 60 Query: 305 KRTIQTAESL-------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYL 357 R+I TA + VP E LNE G + ++ + EE + Y Sbjct: 61 NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN 120 Query: 358 YRY-----------------------------PGGESYQDLVQRLEP-----VIMELERQ 383 P ES +D+++RL P + E+ R Sbjct: 121 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG 180 Query: 384 GNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLH 418 +L+ +H R LL + +++ + P Sbjct: 181 KTILISAHGNSSRALLKHLEGISDEDIINITLPTG 215 >4PZA-A nrPDB Length = 223 Score = 134 bits (337), Expect = 9e-32, Method: Composition-based stats. Identities = 41/164 (25%), Positives = 76/164 (46%), Gaps = 20/164 (12%) Query: 247 VQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQL 304 ++ R + + RHG++++N+ ++ G D+ LS G+ A A + L +++ L + +S L Sbjct: 1 MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQ--PLLIVSSDL 58 Query: 305 KRTIQTA----ESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 +R TA E G+ L E G + +T+A+I+ P L +E + Sbjct: 59 RRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGA-RLAWREDATWAP 117 Query: 361 PGGESYQDLVQRLEPVIMELERQG-----------NVLVISHQA 393 GGES D+ R P++ EL V++++H Sbjct: 118 HGGESRVDVAARSRPLVAELVASEPEWGGADEPDRPVVLVAHGG 161 >3E9D-A nrPDB Length = 265 Score = 81.2 bits (199), Expect = 9e-16, Method: Composition-based stats. Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 27/186 (14%) Query: 252 IYLCRHGESEFNLLGKIGG---DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 + + RHGE+++N + G D+ LS G Q A A ++L++ T+ V+ S L+R I Sbjct: 6 LTIVRHGETQYNRDKLLQGQGIDTPLSDTGHQQAAAAGRYLKDLHFTN--VFVSNLQRAI 63 Query: 309 QTAE-SLGVPYEQWK-------ILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 QTAE LG +L E GV E ++ Q Y Sbjct: 64 QTAEIILGNNLHSSATEMILDPLLRERGFGVAEGRPKEHLKNMANA----AGQSCRDYTP 119 Query: 361 PGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFL-----DKGADELPYLRC 415 PGGE+ + + R + + L ++ + H + + + + D Sbjct: 120 PGGETLEQVKTRFKMFLKSLFQR---MFEEHGSALSSVPSEADQPVIAGLADDGAQ--NV 174 Query: 416 PLHTIF 421 P+H + Sbjct: 175 PVHALM 180 >3HJG-A nrPDB Length = 213 Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 10/159 (6%) Query: 252 IYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKR----T 307 IYL RHG+ + + G + L V+ + Q + + + + +S L R Sbjct: 8 IYLMRHGKVDAAPG--LHGQTDLKVK-EAEQQQIAMAWKTKGYDVAGIISSPLSRCHDLA 64 Query: 308 IQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQ 367 AE +P L E+D G + M + + + + ++ Q + P ES Sbjct: 65 QILAEQQLLPMTTEDDLQEMDFGDFDGMPFDLLTEHW-KKLDAFWQSPAHHSLPNAESLS 123 Query: 368 DLVQRLEPVIMELER--QGNVLVISHQAVMRCLLAYFLD 404 QR+ ++ N+L+++H V+R +LA+ L Sbjct: 124 TFSQRVSRAWSQIINDINDNLLIVTHGGVIRIILAHVLG 162 >3LG2-A nrPDB Length = 292 Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 41/198 (20%), Positives = 71/198 (35%), Gaps = 32/198 (16%) Query: 239 VYYLMNIHVQPRTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRK--FLEEQEI 294 +Y+ + PR I RHG++E++ G+ G D L+ G+ + F Q + Sbjct: 17 LYFQGMPSLTPRCII-VRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNQFL 75 Query: 295 TDL---KVWTSQLKRTIQTAESLGVPYEQWKI----------LNEIDAGVCEEMTYAEI- 340 ++TS R QT + + P + L E + G E M EI Sbjct: 76 NPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYGDYEGMLTREII 135 Query: 341 --EKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELE----------RQGNVLV 388 K + + GE+ Q + RL I ++ R +++V Sbjct: 136 ELRKSRGLDKERPW-NIWRDGCENGETTQQIGLRLSRAIARIQNLHRKHQSEGRASDIMV 194 Query: 389 ISHQAVMRCLLAYFLDKG 406 +H +R A + G Sbjct: 195 FAHGHALRYFAAIWFGLG 212 >3DCY-A nrPDB Length = 275 Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 17/132 (12%) Query: 252 IYLCRHGESEFNLLGKIGG---DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 + + RHGE+ FN I G D LS G + A A FL + ++S L RT Sbjct: 11 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRTK 68 Query: 309 QTAESL--------GVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRY 360 QT + + + L E GV E +E+ +E ++ Sbjct: 69 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAR----EECPVFTP 124 Query: 361 PGGESYQDLVQR 372 PGGE+ + R Sbjct: 125 PGGETLDQVKMR 136 >3R7A-A nrPDB Length = 237 Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 44/202 (21%), Positives = 77/202 (38%), Gaps = 35/202 (17%) Query: 251 TIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTI 308 T+Y+ RHG++ N + G DS L +G + A L L++ I + ++S R I Sbjct: 15 TLYVTRHGKTILNTNHRAQGWADSPLVEKGVEVATNLGTGLKD--IHFMNAYSSDSGRAI 72 Query: 309 QTA-------ESLGVPYEQWKILNEIDAGVCEEMTYAEIEK--------RYPEEF----A 349 +TA E + EQ K L E++ G+ E + PEE Sbjct: 73 ETANLVLKYSEQSKLKLEQRKKLRELNFGIFEGEKLDNMWDAVGKAAGVTSPEELLKFSI 132 Query: 350 LRDQEKYLYRYPG--GESYQDLVQRLEPVIMEL------ERQGNVLVISHQAVMRCLLAY 401 + P E ++ R++ I ++ + GNVLV+ H L+ Sbjct: 133 QEVIDLIRAADPTKQAEDWELFSTRIKAEIDKISEEAAKDGGGNVLVVVHG----LLITT 188 Query: 402 FLDKGADELPYLRCPLHTIFKL 423 ++ L ++ K+ Sbjct: 189 LIEMLDSSKTKLGVENASVTKI 210 >2YN2-A nrPDB Length = 279 Score = 57.7 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 37/188 (19%), Positives = 74/188 (39%), Gaps = 23/188 (12%) Query: 247 VQPRTIYLCRHG-ESEF-------NLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLK 298 + IY+ RHG S + I D LS G + A L ++ + ++ Sbjct: 10 MAIENIYIARHGYRSNWLPKGPYPPPPTGIDNDVPLSEHGVEQAHELANYISKLDVKPEM 69 Query: 299 VWTSQLKRTIQTA----ESLGVPYEQWKILNE---IDAGVCEEMTYAEIEKRYPEEFALR 351 +++S R ++T+ E+L +P + + E D + E E+ ++ Sbjct: 70 IFSSPFYRCLETSKPTVEALKIPLYVDRGVGEWYKPDRPIIPEPATHEVMSKFFPSMISP 129 Query: 352 DQEKYLYRYPGGESYQDLVQRLEP----VIMELERQ----GNVLVISHQAVMRCLLAYFL 403 D E + GE+ +D+ +R I +ER+ +++++H A L L Sbjct: 130 DWEPSIIPSNKGETEEDIFERCHKFWPVFIDRVERKFPNVKTIMIVTHAATKSALGMNLL 189 Query: 404 DKGADELP 411 + + P Sbjct: 190 KFSSAKEP 197 >3F2I-A nrPDB Length = 172 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 29/63 (46%) Query: 252 IYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTA 311 +YL RHG +E G + L+ GKQ + + L + + TS L R QTA Sbjct: 3 LYLIRHGIAEAQKTGIKDEERELTQEGKQKTEKVAYRLVKLGRQFDLIVTSPLIRARQTA 62 Query: 312 ESL 314 E L Sbjct: 63 EIL 65 >3DM5-A nrPDB Length = 443 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 15/110 (13%) Query: 38 PTLIVMIGLPARGKTYVSKKLTRYLNWIG-----VPTKVFNLGVYR--REAVKSYKSYDF 90 PT+++M+G+ GKT KL RY G V + + G Y R+ + Y F Sbjct: 100 PTILLMVGIQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPGAYHQLRQLLDRYHIEVF 159 Query: 91 FRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMI 140 ++A+K+ K+ Y + I + D +E + +I Sbjct: 160 GNPQEKDAIKLAKEGV--------DYFKSKGVDIIIVDTAGRHKEDKALI 201 >3LVQ-E nrPDB Length = 497 Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 40/154 (25%), Positives = 62/154 (40%), Gaps = 19/154 (12%) Query: 34 MTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRH 93 ++N I+M+GL A GKT + KL + +PT FN+ E V +YK+ F Sbjct: 318 LSNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETV-TYKNVKFNVW 371 Query: 94 DNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDAT-----NTTRERRDMILNFAEQNS 148 D KIR + Y T G I V D + R+ I+N E Sbjct: 372 DVGGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 423 Query: 149 FKVFFVESVCDDPDVIAANILEVKVSSPDYPERN 182 + + D PD + + ++ K+ +RN Sbjct: 424 AIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 457 >6BBQ-A nrPDB Length = 520 Score = 37.3 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 19/165 (11%) Query: 23 MSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAV 82 ++K + N I+M+GL A GKT + KL + +PT FN+ E V Sbjct: 344 ANKKGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETV 398 Query: 83 KSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDAT-----NTTRERR 137 +YK+ F D KIR + Y T G I V D + R+ Sbjct: 399 -TYKNVKFNVWDVGGLDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQEL 449 Query: 138 DMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERN 182 I+N E + + D PD + + ++ K+ +RN Sbjct: 450 HRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 494 >2A5F-A nrPDB Length = 175 Score = 36.9 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 40/152 (26%), Positives = 60/152 (39%), Gaps = 19/152 (12%) Query: 36 NSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDN 95 N I+M+GL A GKT + KL + +PT FN+ E V +YK+ F D Sbjct: 11 NKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETV-TYKNVKFNVWDV 64 Query: 96 EEAMKIRKQCALVALEDVKAYLTEENGQIAVFDAT-----NTTRERRDMILNFAEQNSFK 150 KIR + Y T G I V D + R+ I+N E Sbjct: 65 GGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 116 Query: 151 VFFVESVCDDPDVIAANILEVKVSSPDYPERN 182 + + D PD + + ++ K+ +RN Sbjct: 117 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 148 >4XRP-A nrPDB Length = 312 Score = 32.3 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 21/119 (17%) Query: 38 PTLIVMIGLPARGKTYVSKKLTRYL-NWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNE 96 P L++++G P GK+ ++ R NW+ V F L + + + Y+ E Sbjct: 11 PKLLILVGAPGSGKSTFARYFIRTEDNWVRVNRDDFRLMQFGDSLMSPF--YE------E 62 Query: 97 EAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTT-RERRDMILNFAEQNS--FKVF 152 K+ + + L++ + DATN++ R +DM+ + E FKVF Sbjct: 63 RITKMVEASVIALLKNRTN---------VIIDATNSSLRSLQDMVHTYTEYADISFKVF 112 >2V3C-C nrPDB Length = 432 Score = 32.3 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 14 YETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFN 73 YE L KK N +I+++G+ GKT + KL RY+ G+ + Sbjct: 78 YEELVKLLGEEAKKLELNPKKQN---VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIA 134 Query: 74 LGVYRREAVKSYK 86 YR A + K Sbjct: 135 ADTYRPAAYEQLK 147 >5L3R-A nrPDB Length = 301 Score = 31.9 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 19/57 (33%), Positives = 26/57 (45%) Query: 28 CSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKS 84 S + + PT+I++ GL GKT V KL YL G + VYR A+ Sbjct: 96 VSELQFAKSGPTVILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYRPAAIDQ 152 >2YVU-A nrPDB Length = 186 Score = 31.9 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 12/109 (11%) Query: 40 LIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAM 99 ++ + GLP GKT ++ +L L G +V + G + R V + EE + Sbjct: 15 VVWLTGLPGSGKTTIATRLADLLQKEGYRVEVLD-GDWARTTVSEGAGFT-----REERL 68 Query: 100 KIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNS 148 + K+ A +A L NG I + + ++ R+M+ E+ Sbjct: 69 RHLKRIAWIA------RLLARNGVIVICSFVSPYKQARNMVRRIVEEEG 111 >3B9O-A nrPDB Length = 440 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 13/100 (13%) Query: 272 SGLSVRGKQFAQALRK--FLEEQEITDLKVWTSQL-KRTIQTAESLGVPYEQWKILNEID 328 +G+S RG++FA + FL +++ LK + + KR + Y + ++ Sbjct: 227 AGMSERGREFAAKHAECVFLGGKDVETLKFFVDDIRKRAKK--------YGRNPDHIKMF 278 Query: 329 AGVC--EEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESY 366 AG+C T+ E ++ E +L Y GG Y Sbjct: 279 AGICVIVGKTHDEAMEKLNSFQKYWSLEGHLAHYGGGTGY 318 >6FAE-B nrPDB Length = 213 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 41 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMK 100 I+M+GL A GKT + KL +PT FN+ E V+ YK+ F D K Sbjct: 52 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVE-YKNISFTVWDVGGQDK 105 Query: 101 IRKQCALVALEDVKAYLTEENGQIAVFDATNTTR--ERRDMILNFAEQNSFK 150 IR + Y G I V D+ + R E R+ ++ ++ + Sbjct: 106 IRPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 149 >3O47-A nrPDB Length = 329 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 41 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMK 100 I+M+GL A GKT + KL +PT FN+ E V+ YK+ F D K Sbjct: 168 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVE-YKNISFTVWDVGGQDK 221 Query: 101 IRKQCALVALEDVKAYLTEENGQIAVFDATNTTR--ERRDMILNFAEQNSFK 150 IR + Y G I V D+ + R E R+ ++ ++ + Sbjct: 222 IRPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 265 >6DFF-C nrPDB Length = 193 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 41 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMK 100 I+M+GL A GKT + KL +PT FN+ E V+ YK+ F D K Sbjct: 32 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVE-YKNISFTVWDVGGLDK 85 Query: 101 IRKQCALVALEDVKAYLTEENGQIAVFDATNTTR--ERRDMILNFAEQNSFK 150 IR + Y G I V D+ + R E R+ ++ ++ + Sbjct: 86 IRPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 129 >1J2J-A nrPDB Length = 166 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 41 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMK 100 I+M+GL A GKT + KL +PT FN+ E V+ YK+ F D K Sbjct: 5 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVE-YKNISFTVWDVGGLDK 58 Query: 101 IRKQCALVALEDVKAYLTEENGQIAVFDATNTTR--ERRDMILNFAEQNSFK 150 IR + Y G I V D+ + R E R+ ++ ++ + Sbjct: 59 IRPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 102 >3AQ4-A nrPDB Length = 184 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 16/112 (14%) Query: 41 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMK 100 I+M+GL A GKT + KL +PT FN+ E V+ YK+ F D K Sbjct: 23 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVE-YKNISFTVWDVGGQDK 76 Query: 101 IRKQCALVALEDVKAYLTEENGQIAVFDATNTTR--ERRDMILNFAEQNSFK 150 IR + Y G I V D+ + R E RD + ++ + Sbjct: 77 IRPLW--------RHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELR 120 >4YLG-A nrPDB Length = 173 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 7/75 (9%) Query: 29 SWASYMTNSPTL-IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKS 87 SW S + + I+M+GL A GKT + KL +PT FN+ E V+ YK+ Sbjct: 3 SWLSKLLGKKEMRILMVGLDAAGKTSILYKLKLGEIVTTIPTIGFNV-----ETVE-YKN 56 Query: 88 YDFFRHDNEEAMKIR 102 F D KIR Sbjct: 57 ISFTVWDVGGQDKIR 71 >1LFP-A nrPDB Length = 249 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 275 SVRGKQFAQALRKFLEEQEIT-DLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCE 333 + RGK F++ +R+ + + + +L+ I+ A+ +P+E + + AG E Sbjct: 19 AQRGKLFSKLIREIIVATRLGGPNPEFNPRLRTAIEQAKKANMPWENIERAIKKGAGELE 78 Query: 334 EMTYAEI 340 + E+ Sbjct: 79 GEQFEEV 85 >4C0E-A nrPDB Length = 528 Score = 29.6 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 18 TPNLRMSEKKCSWASYMTNSPTLIVMIGLP-ARGKTYVSKKLTRYLNWIGVPTKVFNLGV 76 PNL + C+WA +++ L V++GLP +G +K L ++L +G K F + Sbjct: 184 RPNL-LPGFACAWAGLVSHRAFLPVILGLPDEKGWAPFTKLLEQFLGCVGELVKTFTVSS 242 Query: 77 YRREA 81 +E Sbjct: 243 LGKEM 247 >2IYT-A nrPDB Length = 184 Score = 29.6 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 42 VMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNE-EAMK 100 V++GLP GK+ + ++L + L GV ++ + +R D F D E E + Sbjct: 6 VLVGLPGSGKSTIGRRLAKAL---GVGLLDTDVAIEQRTG---RSIADIFATDGEQEFRR 59 Query: 101 IRKQCALVALEDVKAYLTEENGQI 124 I + AL D L+ G + Sbjct: 60 IEEDVVRAALADHDGVLSLGGGAV 83 >4CMR-A nrPDB Length = 597 Score = 29.6 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 13/84 (15%) Query: 370 VQRLEPVIMELERQGNVLVISHQAVMRCLLA---------YFLDKGADELPYLRCPLHTI 420 +RL PV +E+ + + + R ++ LD+GA + + L+ + Sbjct: 32 SERLSPVALEIREEE----VKGRNWTRAMIKAYEYVDETLRMLDEGAVSVDFEPFTLYMV 87 Query: 421 FKLTPVAYGCKVETIKLNVEAVNT 444 K P YG VET++ +VE T Sbjct: 88 LKYKPKIYGEIVETLETHVEPTVT 111 >1WDT-A nrPDB Length = 665 Score = 28.8 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 43/111 (38%), Gaps = 13/111 (11%) Query: 272 SGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAE-------SLGVPYEQWKIL 324 L +G+ L + L + D + +L+R +T E L + + ++ Sbjct: 385 VALHPKGRTDEARLGEALRKLLEEDPSL---KLERQEETGELLLWGHGELHLATAKERL- 440 Query: 325 NEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEP 375 D GV E + ++ R + Q KY + G Y D+ RLEP Sbjct: 441 --QDYGVEVEFSVPKVPYRETIKKVAEGQGKYKKQTGGHGQYGDVWLRLEP 489 >5HX2-D nrPDB Length = 660 Score = 28.5 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 55/134 (41%), Gaps = 19/134 (14%) Query: 52 TYVSKKLTRYLNWIGVPTKVFNLGVY---RREAVKSYKSYDFFRHDNEEAMKIRKQCALV 108 T V+ +LTR N I ++F G + ++ ++ + F + E ++ C L+ Sbjct: 4 TPVNYQLTRTANAI---PEIFVGGTFAEIKQNLIEWLNGQNEFLDYDFEGSRLNVLCDLL 60 Query: 109 ALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANI 168 A + ++ G AV+++ T R ++ A+ N + P +A Sbjct: 61 AYNTLY---IQQFGNAAVYESFMRTANLRSSVVQAAQDNGYL----------PTSKSAAQ 107 Query: 169 LEVKVSSPDYPERN 182 E+ ++ D RN Sbjct: 108 TEIMLTCTDALNRN 121 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.136 0.378 Lambda K H 0.267 0.0408 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,509,614 Number of Sequences: 36641 Number of extensions: 798728 Number of successful extensions: 2301 Number of sequences better than 10.0: 54 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 45 Number of HSP's that attempted gapping in prelim test: 2128 Number of HSP's gapped (non-prelim): 113 length of query: 505 length of database: 10,336,785 effective HSP length: 101 effective length of query: 404 effective length of database: 6,636,044 effective search space: 2680961776 effective search space used: 2680961776 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)