BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O60701 (494 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3TF5-A nrPDB 1019 0.0 2O3J-A nrPDB 627 e-180 4A7P-A nrPDB 291 4e-79 2Y0D-A nrPDB 257 7e-69 3GG2-A nrPDB 235 3e-62 3VTF-A nrPDB 208 4e-54 1MV8-A nrPDB 128 5e-30 4XRR-A nrPDB 115 6e-26 3PLN-A nrPDB 107 1e-23 4R16-A nrPDB 106 2e-23 3G79-A nrPDB 105 5e-23 1DLI-A nrPDB 94 2e-19 3OJO-A nrPDB 87 1e-17 4J90-A nrPDB 34 0.13 5L8W-A nrPDB 33 0.34 5BUT-A nrPDB 32 0.71 3DUG-A nrPDB 31 0.98 3TCO-A nrPDB 31 1.1 5OQL-y nrPDB 31 1.1 5YFP-H nrPDB 29 4.2 2HMT-A nrPDB 29 4.7 2NPI-A nrPDB 29 6.1 5A4J-A nrPDB 28 7.7 5L8H-A nrPDB 28 8.3 3OT5-A nrPDB 28 9.0 3EIQ-A nrPDB 28 9.6 5GWY-A nrPDB 28 9.8 >3TF5-A nrPDB Length = 493 Score = 1019 bits (2636), Expect = 0.0, Method: Compositional matrix adjust. Identities = 493/494 (99%), Positives = 493/494 (99%), Gaps = 1/494 (0%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV Sbjct: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS Sbjct: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120 Query: 121 NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180 NGYKIVTEKST PVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI Sbjct: 121 NGYKIVTEKST-PVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 179 Query: 181 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 240 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL Sbjct: 180 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 239 Query: 241 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 300 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW Sbjct: 240 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 299 Query: 301 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 360 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE Sbjct: 300 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 359 Query: 361 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 420 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF Sbjct: 360 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 419 Query: 421 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP 480 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP Sbjct: 420 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP 479 Query: 481 KFSLQDPPNKKPKV 494 KFSLQDPPNKKPKV Sbjct: 480 KFSLQDPPNKKPKV 493 >2O3J-A nrPDB Length = 481 Score = 627 bits (1616), Expect = e-180, Method: Compositional matrix adjust. Identities = 304/463 (65%), Positives = 368/463 (79%), Gaps = 6/463 (1%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVE 62 ++ K+ C+GAGYVGGPTC++IAH CP I VTVVD+N ++I WNS LPIYEPGL E+V Sbjct: 8 KVSKVVCVGAGYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLDEIVF 67 Query: 63 SCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNG 122 + RG+NLFFS++I AI EADL+FISVNTPTK YG GKG A DLKY+E+ +R I Q + G Sbjct: 68 AARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMAPDLKYVESVSRTIAQYAGG 127 Query: 123 YKIVTEKSTVPVRAAESIRRIFDANTKPNLNL--QVLSNPEFLAEGTAIKDLKNPDRVLI 180 KIV EKSTVPV+AAESI I K N NL QVLSNPEFLAEGTA+KDL NPDRVLI Sbjct: 128 PKIVVEKSTVPVKAAESIGCILREAQKNNENLKFQVLSNPEFLAEGTAMKDLANPDRVLI 187 Query: 181 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 240 GG+ +PEG +AV L +YE+WVPR +I+TTNTWSSELSKL ANAFLAQRISSINSISA+ Sbjct: 188 GGESSPEGLQAVAELVRIYENWVPRNRIITTNTWSSELSKLVANAFLAQRISSINSISAV 247 Query: 241 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 300 CEATGA++ EVA A+G D RIG+KFL+ASVGFGGSCFQKDVL+LVYLCE+LNLP+VA YW Sbjct: 248 CEATGAEISEVAHAVGYDTRIGSKFLQASVGFGGSCFQKDVLSLVYLCESLNLPQVADYW 307 Query: 301 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 360 Q VI++N++QRRRFA +II LFNTVTDKKIAI GFAFKK+TGDTRESS+I++ K+LM+E Sbjct: 308 QGVININNWQRRRFADKIIAELFNTVTDKKIAIFGFAFKKNTGDTRESSAIHVIKHLMEE 367 Query: 361 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 420 A L +YDPKV + Q++ DL+ ++D V RL+T+ DPY A GAHA+V+ TEWD F Sbjct: 368 HAKLSVYDPKVQKSQMLNDLASVTSAQD--VERLITVESDPYAAARGAHAIVVLTEWDEF 425 Query: 421 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIG 463 EL+Y +IH M PA IFDGR +LD L+ IGF+ IG Sbjct: 426 VELNYSQIHNDMQHPAAIFDGRLILD--QKALREIGFRTFAIG 466 >4A7P-A nrPDB Length = 446 Score = 291 bits (746), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 181/462 (39%), Positives = 251/462 (54%), Gaps = 32/462 (6%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES-C 64 +I IG GYVG + + + E V VD + +I + +PIYEPGL +V S Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHE--VVCVDKDARKIELLHQNVMPIYEPGLDALVASNV 67 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 + L F+T++ + +K+AD VFI+V TP++ G G A DL Y+ A AR I +N Sbjct: 68 KAGRLSFTTDLAEGVKDADAVFIAVGTPSRR---GDGHA-DLSYVFAAAREIAENLTKPS 123 Query: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184 ++ KSTVPV + + RI A PN +V+SNPEFL EG AI+D K PDRV++G Sbjct: 124 VIVTKSTVPVGTGDEVERII-AEVAPNSGAKVVSNPEFLREGAAIEDFKRPDRVVVG--- 179 Query: 185 TPEGQRAVQALCAVYEHWVPREK--ILTTNTWSSELSKLAANAFLAQRISSINSISALCE 242 E + A Q + +Y + +L T +SEL K AANAFLA +I+ IN I+ LCE Sbjct: 180 -TEDEFARQVMREIYRPLSLNQSAPVLFTGRRTSELIKYAANAFLAVKITFINEIADLCE 238 Query: 243 ATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQ 302 GADV+EV+ IGMD RIG KFL A G+GGSCF KD L L+ P R + Sbjct: 239 QVGADVQEVSRGIGMDNRIGGKFLHAGPGYGGSCFPKDTLALMKTAADNETP--LRIVEA 296 Query: 303 VIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGA 362 + +ND ++R ++I ++ V K + ILG FK +T D R++ S+ I L D GA Sbjct: 297 TVQVNDARKRAMGRKVIKAMGGDVRGKTVGILGLTFKPNTDDMRDAPSLSIIAALQDAGA 356 Query: 363 HLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKE 422 + YDP+ GV + ++ V ++PY A DGA A+VI TEWD F+ Sbjct: 357 TVKAYDPE-------------GVEQASKMLTDVEFVENPYAAADGADALVIVTEWDAFRA 403 Query: 423 LDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464 LD RI K LK + D R + EL+ G Q +GK Sbjct: 404 LDLTRI-KNSLKSPVLVDLRNIYP--PAELERAGLQYTGVGK 442 >2Y0D-A nrPDB Length = 478 Score = 257 bits (657), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 173/483 (35%), Positives = 259/483 (53%), Gaps = 27/483 (5%) Query: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66 + IG+G VG T + +A + + V +DV++++I+ N+ +PI+EPGLKEV+ R Sbjct: 11 LTIIGSGKVGLVTGACLADIGHD--VFCLDVDQAKIDILNNGGVPIHEPGLKEVIARNRS 68 Query: 67 KN-LFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 L FST+I+ A+ D+ FI+V TP G +ADL+Y+ A AR I + G+K+ Sbjct: 69 AGRLRFSTDIEAAVAHGDVQFIAVGTPPDEDG-----SADLQYVLAAARNIGRYMTGFKV 123 Query: 126 VTEKSTVPVRAAESIRRIFD---ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGG 182 + +KSTVPV AE +R A + V+SNPEFL EG A+ D PDR++IG Sbjct: 124 IVDKSTVPVGTAERVRAAVAEELAKRGGDQMFSVVSNPEFLKEGAAVDDFTRPDRIVIGC 183 Query: 183 DETPEGQRAVQALCAVYEHW-VPREKILTTNTWSSELSKLAANAFLAQRISSINSISALC 241 D+ G+RA + + +Y + E+ L + S+E +K AANA LA RIS +N ++ L Sbjct: 184 DDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLA 243 Query: 242 EATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQ 301 + GAD+E V IG D RIG FL A G+GGSCF KDV L+ + + + + Sbjct: 244 DRFGADIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHG--QSLQILK 301 Query: 302 QVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361 V +N Q+R A +I+ +T + AI G AFK +T D RE+ S + L+ G Sbjct: 302 AVSSVNATQKRVLADKIVARFGEDLTGRTFAIWGLAFKPNTDDMREAPSRELIAELLSRG 361 Query: 362 AHLHIYDP---KVPREQIVVDLS-HPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEW 417 A + YDP + R I +DL+ HP E RL + D +A A A+VI TEW Sbjct: 362 ARIAAYDPVAQEEARRVIALDLADHPSWLE-----RL-SFVDDEAQAARDADALVIVTEW 415 Query: 418 DMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSG 477 +FK D+ + ++ K IFDGR + + + G + IG+ S + + +G Sbjct: 416 KIFKSPDFVAL-GRLWKTPVIFDGRNLYE--PETMSEQGIEYHPIGRPGSRQAVAARVTG 472 Query: 478 EIP 480 P Sbjct: 473 TAP 475 >3GG2-A nrPDB Length = 450 Score = 235 bits (600), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 150/449 (33%), Positives = 232/449 (51%), Gaps = 39/449 (8%) Query: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGL-KEVVESCR 65 I +G GYVG + + A + +R +D + ++I NS T+PIYEPGL K + + + Sbjct: 5 IAVVGIGYVGLVSATCFAELGANVRC--IDTDRNKIEQLNSGTIPIYEPGLEKMIARNVK 62 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 L F T I+ A+ EAD++FI+V TP G+ +AD+ Y+ AR I + + Y + Sbjct: 63 AGRLRFGTEIEQAVPEADIIFIAVGTPA-----GEDGSADMSYVLDAARSIGRAMSRYIL 117 Query: 126 VTEKSTVPVRAAESIRRIFDANTKPN---LNLQVLSNPEFLAEGTAIKDLKNPDRVLIGG 182 + KSTVPV + IR+ ++ + SNPEFL EG AI D PDRV++G Sbjct: 118 IVTKSTVPVGSYRLIRKAIQEELDKREVLIDFDIASNPEFLKEGNAIDDFMKPDRVVVGV 177 Query: 183 DETPEGQRAVQALCAVYEHWVPRE-KILTTNTWSSELSKLAANAFLAQRISSINSISALC 241 D RA + + ++Y+ + ++L + S+E++K AANA LA RIS +N ++ LC Sbjct: 178 DS----DRARELITSLYKPMLLNNFRVLFMDIASAEMTKYAANAMLATRISFMNDVANLC 233 Query: 242 EATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQ 301 E GADV V IG D RIG+KFL G+GGSCF KDV L+ E Y Sbjct: 234 ERVGADVSMVRLGIGSDSRIGSKFLYPGCGYGGSCFPKDVKALIRTAEDNG------YRM 287 Query: 302 QVID----MNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYL 357 +V++ +N+ Q+ + V + +AI G +FK T D RE+ S+ + + L Sbjct: 288 EVLEAVERVNEKQKSILFDKFSTYYKGNVQGRCVAIWGLSFKPGTDDMREAPSLVLIEKL 347 Query: 358 MDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEW 417 ++ G + +YDP +E ++ V + D Y+A GA A+ TEW Sbjct: 348 LEVGCRVRVYDPVAMKEA------------QKRLGDKVEYTTDMYDAVRGAEALFHVTEW 395 Query: 418 DMFKELDYERIHKKMLKPAFIFDGRRVLD 446 F+ D+ + + M + + DGR V + Sbjct: 396 KEFRMPDWSALSQAM-AASLVIDGRNVYE 423 >3VTF-A nrPDB Length = 444 Score = 208 bits (530), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 145/448 (32%), Positives = 221/448 (49%), Gaps = 44/448 (9%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVV- 61 + + +G GYVG + RV DVN S + + IYEPGL+E + Sbjct: 20 HMASLSVLGLGYVG--VVHAVGFALLGHRVVGYDVNPSIVERLRAGRPHIYEPGLEEALG 77 Query: 62 ESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACAR---RIVQ 118 + L F+ + ++A+ D FI+V TP G +ADL+Y+EA AR R ++ Sbjct: 78 RALSSGRLSFAESAEEAVAATDATFIAVGTPPAPDG-----SADLRYVEAAARAVGRGIR 132 Query: 119 NSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRV 178 + +V KSTVP E + A + V SNPEFL EG+A++D PDR+ Sbjct: 133 AKGRWHLVVVKSTVPPGTTEGLVARAVAEEAGGVKFSVASNPEFLREGSALEDFFKPDRI 192 Query: 179 LIG-GDETPEGQRAVQALCAVYEHW-VPREKILTTNTWSSELSKLAANAFLAQRISSINS 236 +IG GDE RA L VY+ P+ L +EL K A+N FLA +IS N Sbjct: 193 VIGAGDE-----RAASFLLDVYKAVDAPK---LVMKPREAELVKYASNVFLALKISFANE 244 Query: 237 ISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEV 296 + L + G D V A+G+D+RIG + A +GFGGSCF KD L + E+L L E+ Sbjct: 245 VGLLAKRLGVDTYRVFEAVGLDKRIGRHYFGAGLGFGGSCFPKDTLAFIRFGESLGL-EM 303 Query: 297 ARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKY 356 A + V+ +N+Y R+A ++++ + + + +LG AFK +T D RES + +++ Sbjct: 304 A-ISKAVLRVNEYM-PRYAVQLLEERLGGLRGRHVGVLGLAFKPNTDDVRESRGVEVARL 361 Query: 357 LMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTE 416 L++ GA ++++DP + V + VT +DP D V+I T Sbjct: 362 LLERGARVYVHDPMAMEKARAV------------LGDSVTYVEDPQALLDQVEGVIIATA 409 Query: 417 WDMFKELDYERIHKKMLKPAFIFDGRRV 444 W ++ LDY + + DGR V Sbjct: 410 WPQYEGLDY--------RGKVVVDGRYV 429 >1MV8-A nrPDB Length = 436 Score = 128 bits (322), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 108/386 (27%), Positives = 171/386 (44%), Gaps = 51/386 (13%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 +I G GYVG ++ E V VDV+ ++I+ N PI EPGL+ +++ R Sbjct: 2 RISIFGLGYVGAVCAGCLSARGHE--VIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGR 59 Query: 66 GKN-LFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI----VQNS 120 L +T+ A+ ++D+ FI V TP+K G DL YIE R I + S Sbjct: 60 QTGRLSGTTDFKKAVLDSDVSFICVGTPSKKNG-----DLDLGYIETVCREIGFAIREKS 114 Query: 121 NGYKIVTEKSTVPVRAAESIRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRV 178 + +V + +P + + + + K ++ V +NPEFL E TAIKD P Sbjct: 115 ERHTVVVRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMT 174 Query: 179 LIG------GDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRIS 232 +IG GD E R + A I+ +E+ K N + A +++ Sbjct: 175 VIGELDKQTGDLLEEIYRELDA------------PIIRKTVEVAEMIKYTCNVWHAAKVT 222 Query: 233 SINSISALCEATGADVEEVATAIGMDQRI--GNKFLKASVGFGGSCFQKDVLNLVYLCEA 290 N I + +A G D EV I D ++ +++ FGGSC KDV L Y Sbjct: 223 FANEIGNIAKAVGVDGREVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQ 282 Query: 291 LNL--PEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTD---KKIAILGFAFKKDTGDT 345 L++ P + R S + F+ +T +K+ +LG +FK T D Sbjct: 283 LDVEHPMLGSLM------------RSNSNQVQKAFDLITSHDTRKVGLLGLSFKAGTDDL 330 Query: 346 RESSSIYISKYLMDEGAHLHIYDPKV 371 RES + +++ L+ +G L I+D V Sbjct: 331 RESPLVELAEMLIGKGYELRIFDRNV 356 >4XRR-A nrPDB Length = 456 Score = 115 bits (287), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 123/468 (26%), Positives = 192/468 (41%), Gaps = 37/468 (7%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 K+ GAGYVG TC + V VD + + + + EPGL V Sbjct: 17 KVVIAGAGYVG--TCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLA 74 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 ++ D + AD+V ++V TPT G D + + AC +I ++ Sbjct: 75 ATGRLTASTSYDPVGAADVVIVTVGTPTDA---GHEMVTD-QLVAAC-EQIAPRLRAGQL 129 Query: 126 VTEKSTV-PVRAAESIRRIFDANTKPN-LNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183 V KSTV P + + ++ + + + PE LAEG A+ ++ V++GG Sbjct: 130 VILKSTVSPGTTRTLVAPLLESGGLVHERDFGLAFCPERLAEGVALAQVRTLP-VVVGG- 187 Query: 184 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243 G R+ A + + + + S+E+ KLA N ++ ++ N ++ C Sbjct: 188 ---CGPRSAAAAERFWRSALGVDVRQVPSAESAEVVKLATNWWIDANVAIANELARYCAV 244 Query: 244 TGADVEEVATAIGMDQRIGN--KFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQ 301 G DV +V A + + L VG GGSC KD + + + R + Sbjct: 245 LGVDVLDVIGAANTLPKGSSMVNLLLPGVGVGGSCLTKD--PWMAWRDGRDRGVSLRTVE 302 Query: 302 QVIDMNDYQRRRFASRIIDSLFNTVTDKK---IAILGFAFKKDTGDTRESSSIYISKYLM 358 +ND R A+ I D L D+ IA+LG AFK DTGD R + + L Sbjct: 303 TARAVNDDMPRHTAAVIADELVKLGRDRNDTTIAVLGAAFKNDTGDVRNTPVRGVVAALR 362 Query: 359 DEGAHLHIYDPKVPREQIVVDL-SHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEW 417 D G + I+DP +IV + P S D+ VS GA + Sbjct: 363 DSGFRVRIFDPLADPAEIVARFGTAPAASLDEAVS--------------GAGCLAFLAGH 408 Query: 418 DMFKELDYERIHKKMLKPAFIFDGRRVLDGLH-NELQTIGFQIETIGK 464 F ELD+ + +++ +P +FDGR L EL GF IG+ Sbjct: 409 RQFHELDFGALAERVDEPCLVFDGRMHLPPARIRELHRFGFAYRGIGR 456 >3PLN-A nrPDB Length = 424 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 108/372 (29%), Positives = 172/372 (46%), Gaps = 38/372 (10%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVE 62 E KI G GYVG +IA V +D+ +++++ N PI + KE+ E Sbjct: 35 EFMKITISGTGYVGLSNGVLIAQNH---EVVALDIVQAKVDMLNQKISPIVD---KEIQE 88 Query: 63 SCRGKNLFFSTNID--DAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQ-N 119 K L F D DA + AD V I+ TPT K + +EA R + + N Sbjct: 89 YLAEKPLNFRATTDKHDAYRNADYVIIA--TPTDY--DPKTNYFNTSTVEAVIRDVTEIN 144 Query: 120 SNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNL-QVLSNPEFLAEGTAIKDLKNPDRV 178 N I+ KST+PV F + K L + V+ +PEFL EG A+ D +P R+ Sbjct: 145 PNAVMII--KSTIPVG--------FTRDIKERLGIDNVIFSPEFLREGRALYDNLHPSRI 194 Query: 179 LIGGDETPEGQRAVQALC-AVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSI 237 +IG + + +R L + +P L T++ +E KL AN +LA R++ N + Sbjct: 195 VIG-ERSARAERFADLLKEGAIKQDIP---TLFTDSTEAEAIKLFANTYLALRVAYFNEL 250 Query: 238 SALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVA 297 + E+ G + +++ + +D RIGN + S G+GG C KD L+ E++ +A Sbjct: 251 DSYAESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIA 310 Query: 298 RYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYL 357 ++D N R+ F I DS+ K + + K + + R SS I K + Sbjct: 311 ----AIVDAN-RTRKDF---IADSIL-ARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRI 361 Query: 358 MDEGAHLHIYDP 369 +G + IY+P Sbjct: 362 KAKGIPVIIYEP 373 >4R16-A nrPDB Length = 418 Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 120/470 (25%), Positives = 194/470 (41%), Gaps = 67/470 (14%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPG----LKEVV 61 +I +G GY+G PT + A + V D+ I NS I EP LKEV+ Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYD--VVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVL 59 Query: 62 ESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSN 121 + L + ++D +K +++ I V TP G DL Y+E R + + + Sbjct: 60 SLGK---LKVTDRVED-LKGSNVFIICVQTPLS------GDDPDLSYLERAIRTVAEVMD 109 Query: 122 GYKIVTEKSTVPVRAAESIRRIFDANT--KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVL 179 +V +ST+P E + R+ + T + ++ V PE + G K+L R++ Sbjct: 110 RGALVIIESTIPPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRII 169 Query: 180 IGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISA 239 G E +A +Y +V + +I TN ++E+ KL N F I+ N + Sbjct: 170 GGVSE-----KAANLAEKLYRSFV-KGRIFLTNATTAEMVKLMENTFRDVNIALANEFAL 223 Query: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVAR 298 L G +V E R+ K +G GG C KD L L E L +AR Sbjct: 224 LAHQYGVNVYEAIELANTHPRV--KIHTPGIGVGGHCLPKDPYLLLSNAKEDFGLIRIAR 281 Query: 299 YWQQVIDMNDYQRRRFASRIIDSLFNTVTDKK----IAILGFAFKKDTGDTRESSSIYIS 354 + + FA+ ++ K IA+LG A+K T DTR S ++ Sbjct: 282 RINE-------RMPAFAAGLLFEALEKANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFV 334 Query: 355 KYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVIC 414 + + + + YDP V D + ++V +GA A+VI Sbjct: 335 EIIRNSVKEVRTYDPYVR-------------GTHDSLEKVV----------EGADAIVIA 371 Query: 415 TEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464 T+ FK +++E I K M + I DGR ++ + +GF IG+ Sbjct: 372 TDHPEFKSVNWESIGKSM-RHKIIIDGRNII-----KEPPVGFIFRGIGR 415 >3G79-A nrPDB Length = 478 Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 122/484 (25%), Positives = 208/484 (42%), Gaps = 52/484 (10%) Query: 4 IKKICCIGAGYVGGPTCSVIAHM-CPEIRVTVVDVNES---RINAWNSPTLPIY--EPGL 57 IKKI +G GYVG P + A C E + ++S +I N P+ EPGL Sbjct: 18 IKKIGVLGMGYVGIPAAVLFADAPCFEKVLGFQRNSKSSGYKIEMLNRGESPLKGEEPGL 77 Query: 58 KEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIV 117 +E++ F T I E D V +++ TP + K D + R + Sbjct: 78 EELIGKVVKAGKFECTPDFSRISELDAVTLAIQTP---FANPKDLEPDFSALIDGIRNVG 134 Query: 118 QNSN-GYKIVTEKSTVPVRAAESIRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKN 174 + G +V E + P ++I + + K + + PE + G +K+++ Sbjct: 135 KYLKPGMLVVLESTITPGTTEGMAKQILEEESGLKAGEDFALAHAPERVMVGRLLKNIRE 194 Query: 175 PDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSI 234 DR+ +GG + +RAV+ +Y + +++ + ++E++K A N F +I++I Sbjct: 195 HDRI-VGGIDEASTKRAVE----LYSPVLTVGQVIPMSATAAEVTKTAENTFRDLQIAAI 249 Query: 235 NSISALCEATGADVEEVATAIGMDQRIGNKFLKA----SVGFGGSCFQKDVLNL---VYL 287 N ++ CEA G +V +V T G+D G +A G GG C KD +L V + Sbjct: 250 NQLALYCEAMGINVYDVRT--GVDSLKGEGITRAVLWPGAGVGGHCLTKDTYHLERGVKI 307 Query: 288 CEA-LNLPEVAR----YWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDT 342 L+ PE A ++V D ++ L + K+A+LG+AF KD+ Sbjct: 308 GRGELDYPEGADSIYVLARKVNDFMPAHMYNLTVAALERLGKKMDGSKVAMLGWAFIKDS 367 Query: 343 GDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPY 402 D R + S + GA + ++DP V +++PGV D + +V Sbjct: 368 DDARNTPSEPYRDLCLKAGASVMVHDPYV--------VNYPGVEISDNLEEVVR------ 413 Query: 403 EACDGAHAVVICTEWDMFKELDYERIHKKMLKP-AFIFDGRRVLDGLHNELQTIGFQIET 461 A A+V+ + L + K K I DGR V++ +E GF + Sbjct: 414 ----NADAIVVLAGHSAYSSLKADWAKKVSAKANPVIIDGRNVIE--PDEFIGKGFVYKG 467 Query: 462 IGKK 465 IG++ Sbjct: 468 IGRE 471 >1DLI-A nrPDB Length = 402 Score = 93.6 bits (231), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 91/371 (24%), Positives = 172/371 (46%), Gaps = 29/371 (7%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 KI G+GYV S+ + + VT+VD+ S+++ N+ PI + ++ ++S Sbjct: 2 KIAVAGSGYV---GLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKS-- 56 Query: 66 GKNLFFSTNIDD--AIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGY 123 K L +D A KEA+LV I+ TPT Y + D +++E + ++ + N + Sbjct: 57 -KQLSIKATLDSKAAYKEAELVIIA--TPT-NYN-SRINYFDTQHVETVIKEVL-SVNSH 110 Query: 124 KIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183 + KST+P+ +R+ F + +++ +PEFL E A+ D P R+++ + Sbjct: 111 ATLIIKSTIPIGFITEMRQKFQTD-------RIIFSPEFLRESKALYDNLYPSRIIVSCE 163 Query: 184 E--TPEGQRAVQALCAVYEHWVPREKI--LTTNTWSSELSKLAANAFLAQRISSINSISA 239 E +P+ + + + + + + L +E KL AN +LA R++ N + Sbjct: 164 ENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDT 223 Query: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299 E+ + + I D RIG + S G+GG C KD L L N+P+ Sbjct: 224 YAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQL--LANYNNIPQTL-- 279 Query: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTD-KKIAILGFAFKKDTGDTRESSSIYISKYLM 358 + ++ N+ ++ A +II+ L + K + + K ++ + RES+ + L Sbjct: 280 IEAIVSSNNVRKSYIAKQIINVLKEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILK 339 Query: 359 DEGAHLHIYDP 369 + + IY+P Sbjct: 340 SKDIKIIIYEP 350 >3OJO-A nrPDB Length = 431 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 106/451 (23%), Positives = 189/451 (41%), Gaps = 64/451 (14%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 K+ +G GY+G PT + A + V VD+N+ I+ + + I EPGL+EV E Sbjct: 13 KLTVVGLGYIGLPTSIMFAKHG--VDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVL 70 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQN-SNGYK 124 + +A +D+ I+V TP + R+ D+ + I+ G Sbjct: 71 SSGKLKVSTTPEA---SDVFIIAVPTPNND---DQYRSCDISLVMRALDSILPFLKKGNT 124 Query: 125 IVTEKSTVPVRAAESIRRIFDANTKPNL------NLQVLSNPEFLAEGTAIKDLKNPDRV 178 I+ E + P + ++ + + NL ++ ++ PE + G +++L + +R+ Sbjct: 125 IIVESTIAPKTMDDFVKPVIE-----NLGFTIGEDIYLVHCPERVLPGKILEELVHNNRI 179 Query: 179 LIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSIS 238 IGG + ++A VY +V E I T+ ++E+SKL N + I+ N ++ Sbjct: 180 -IGG----VTKACIEAGKRVYRTFVQGEMI-ETDARTAEMSKLMENTYRDVNIALANELT 233 Query: 239 ALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVAR 298 +C +V +V R+ + G GG C D Y A + PE A+ Sbjct: 234 KICNNLNINVLDVIEMANKHPRV--NIHQPGPGVGGHCLAVD----PYFIIAKD-PENAK 286 Query: 299 YWQQVIDMNDYQRRRFASRIIDS---LFNTVTDKKIAILGFAFKKDTGDTRESSSIYISK 355 Q ++N+ + ++D+ + ++ K+ + G +K D D RES + I + Sbjct: 287 LIQTGREINN----SMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYE 342 Query: 356 YLMDE-GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVIC 414 L E + YDP V + + D+SH A A V+I Sbjct: 343 LLNQEPDIEVCAYDPHVELDFVEHDMSH---------------------AVKDASLVLIL 381 Query: 415 TEWDMFKELDYERIHKKMLKPAFIFDGRRVL 445 ++ FK L K +K IFD + V+ Sbjct: 382 SDHSEFKNLSDSHFDK--MKHKVIFDTKNVV 410 >4J90-A nrPDB Length = 222 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNS 47 K+ IG G GG C + M E V VD+NE ++NA+ S Sbjct: 7 KQFAVIGLGRFGGSICKELHRMGHE--VLAVDINEEKVNAYAS 47 >5L8W-A nrPDB Length = 376 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 15/58 (25%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 231 ISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLC 288 + +++ +++C GA+ + IG +Q N+ V FG +C+ VL +Y C Sbjct: 10 LMTVSKFASIC-TMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFC 66 >5BUT-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.71, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNS 47 K+ IG G GG + M E V VD+NE ++NA+ S Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGHE--VLAVDINEEKVNAYAS 47 Score = 32.0 bits (71), Expect = 0.71, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNS 47 K+ IG G GG + M E V VD+NE ++NA+ S Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGHE--VLAVDINEEKVNAYAS 189 >3DUG-A nrPDB Length = 408 Score = 31.2 bits (69), Expect = 0.98, Method: Compositional matrix adjust. Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 5/98 (5%) Query: 344 DTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDP-- 401 +T S I++S Y++ EGA I + + +E++V + ++T D Sbjct: 261 NTVLSMDIFVSDYILGEGAKAGIREESLNKERLVGKKQRENFMNAHRRGAIITFGTDAGI 320 Query: 402 YEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIF 439 ++ D A EW M E I +K A +F Sbjct: 321 FDHGDNAKQFAYMVEWGM---TPLEAIQASTIKTATLF 355 >3TCO-A nrPDB Length = 109 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Query: 45 WNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPT 93 W +P +YEP K+V E +GK +F N+D+ K AD + +N PT Sbjct: 32 WCAPC-HLYEPIYKKVAEKYKGKAVFGRLNVDENQKIAD-KYSVLNIPT 78 >5OQL-y nrPDB Length = 136 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 25/37 (67%), Gaps = 3/37 (8%) Query: 366 IYDPKVPREQIVVDLSHPG---VSEDDQVSRLVTISK 399 I +P + R+Q+VVD+ HPG +S+D+ +L T+ K Sbjct: 16 IRNPLLSRKQMVVDILHPGRPNISKDELREKLATMYK 52 >5YFP-H nrPDB Length = 753 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 6/48 (12%) Query: 407 GAHAVVICTEW------DMFKELDYERIHKKMLKPAFIFDGRRVLDGL 448 GA I +W + FK +D + ++ +ML P I R+ +DGL Sbjct: 683 GAKISSILVDWCSDEVDNHFKLIDKQLLNDEMLSPGSIKSSRKQIDGL 730 >2HMT-A nrPDB Length = 144 Score = 28.9 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNS 47 K+ IG G GG + M E V VD+NE ++NA+ S Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGHE--VLAVDINEEKVNAYAS 47 >2NPI-A nrPDB Length = 460 Score = 28.9 bits (63), Expect = 6.1, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 29/50 (58%), Gaps = 3/50 (6%) Query: 149 KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAV-QALCA 197 KPN ++ + N F+ E + + + P V++GG +T G+ ++ + LC+ Sbjct: 113 KPNHTMKYIYNLHFMLEKIRMSNFEGPRVVIVGGSQT--GKTSLSRTLCS 160 >5A4J-A nrPDB Length = 559 Score = 28.5 bits (62), Expect = 7.7, Method: Compositional matrix adjust. Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 207 KILTTNTWSSELSKLAANAFLAQRISSINSISAL-CEATGADVEEVATAIGMDQRIGNKF 265 K TT L +L NA +A R S+ + + A G +V ++ F Sbjct: 73 KTTTTVGLGDALRRLGKNAMIALREPSLGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDF 132 Query: 266 LKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRR 312 ++G + + N +Y LN+ W++ +DMND Q R Sbjct: 133 --HAIGAANNLLAAMIDNHIYQGNELNIDPRRITWKRCVDMNDRQLR 177 >5L8H-A nrPDB Length = 359 Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 24/58 (41%) Query: 245 GADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQ 302 G + + IG +Q N+ V FG +C+ VL +Y C +A QQ Sbjct: 6 GTNASALEKDIGPEQFPINEHYFGLVNFGNTCYVNSVLQALYFCRPFRENVLAYKAQQ 63 >3OT5-A nrPDB Length = 403 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 15/72 (20%) Query: 127 TEKSTVPVRAA-----ESIRRIFDANTKPNLNLQVLSNPEFLAEGTA--------IKDLK 173 T +STV + A + + IFD KP+++L ++ + LAE T+ + + Sbjct: 56 TFESTVVITAQHREMLDQVLEIFD--IKPDIDLDIMKKGQTLAEITSRVMNGINEVIAAE 113 Query: 174 NPDRVLIGGDET 185 NPD VL+ GD T Sbjct: 114 NPDIVLVHGDTT 125 >3EIQ-A nrPDB Length = 414 Score = 28.1 bits (61), Expect = 9.6, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 57/212 (26%) Query: 87 ISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDA 146 I V TP + + M R KYI+ ++ E + R + +I+D Sbjct: 162 IIVGTPGRVFDMLNRRYLSPKYIKMF------------VLDEADEMLSRGFKD--QIYDI 207 Query: 147 NTKPNLNLQVL----SNPEFLAEGTAIKDLKNPDRVLIGGDE-TPEGQRA---------- 191 K N N QV+ + P + E T K +++P R+L+ +E T EG R Sbjct: 208 FQKLNSNTQVVLLSATMPSDVLEVTK-KFMRDPIRILVKKEELTLEGIRQFYINVEREEW 266 Query: 192 -VQALCAVYEHWVPREKILTTNT-----WSSELSKLAANAFLAQRI-------------- 231 + LC +YE + ++ NT W +E K+ A F + Sbjct: 267 KLDTLCDLYETLTITQAVIFINTRRKVDWLTE--KMHARDFTVSAMHGDMDQKERDVIMR 324 Query: 232 -----SSINSISALCEATGADVEEVATAIGMD 258 SS I+ A G DV++V+ I D Sbjct: 325 EFRSGSSRVLITTDLLARGIDVQQVSLVINYD 356 >5GWY-A nrPDB Length = 308 Score = 28.1 bits (61), Expect = 9.8, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 16/76 (21%) Query: 223 ANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVL 282 AN + + +SS+ S L TG VE++ +I GFGG K++L Sbjct: 241 ANGYTS--VSSVECYSILAAKTGVSVEQLLASIQHLHE----------GFGG----KNIL 284 Query: 283 NLVYLCEALNLPEVAR 298 LC+ L EV + Sbjct: 285 GYSSLCDEFTLAEVVK 300 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3TF5-A nrPDB 704 0.0 2O3J-A nrPDB 569 e-163 2Y0D-A nrPDB 523 e-149 4A7P-A nrPDB 476 e-134 3GG2-A nrPDB 473 e-134 3VTF-A nrPDB 411 e-115 3G79-A nrPDB 410 e-115 4XRR-A nrPDB 407 e-114 4R16-A nrPDB 404 e-113 3OJO-A nrPDB 386 e-107 1MV8-A nrPDB 356 2e-98 3PLN-A nrPDB 338 3e-93 1DLI-A nrPDB 335 3e-92 Sequences not found previously or not previously below threshold: 4GBJ-A nrPDB 51 2e-06 1A5Z-A nrPDB 48 8e-06 2HJR-A nrPDB 46 3e-05 1GUZ-A nrPDB 46 3e-05 1GV0-A nrPDB 46 5e-05 1VPD-A nrPDB 45 6e-05 4DYD-A nrPDB 44 2e-04 4PLW-A nrPDB 44 2e-04 2BC1-A nrPDB 42 5e-04 4OM8-A nrPDB 42 6e-04 3PQF-A nrPDB 42 6e-04 3HWR-A nrPDB 42 7e-04 5XVH-A nrPDB 39 0.004 5Y8M-A nrPDB 39 0.005 1HYH-A nrPDB 39 0.005 5A9T-A nrPDB 39 0.005 1HYE-A nrPDB 38 0.008 3TL2-A nrPDB 38 0.009 3NEP-X nrPDB 38 0.010 4WLE-A nrPDB 38 0.011 4PLF-A nrPDB 37 0.013 6ACQ-A nrPDB 37 0.013 6H9S-A nrPDB 37 0.015 1NHQ-A nrPDB 37 0.020 5ER0-A nrPDB 37 0.025 5JE8-A nrPDB 36 0.040 1Y6J-A nrPDB 36 0.046 6IHE-A nrPDB 36 0.046 1PZF-A nrPDB 36 0.051 4YWO-A nrPDB 36 0.054 1MLD-A nrPDB 36 0.054 2CFY-A nrPDB 36 0.058 5AYV-A nrPDB 36 0.059 1DXL-A nrPDB 35 0.075 5JFC-L nrPDB 35 0.088 4UEJ-A nrPDB 35 0.099 3ZZN-A nrPDB 35 0.100 3L8K-A nrPDB 34 0.10 3WSV-A nrPDB 34 0.11 5U8W-A nrPDB 34 0.11 5VJ7-A nrPDB 34 0.12 4LN1-A nrPDB 34 0.12 3GVH-A nrPDB 34 0.12 2R9Z-A nrPDB 34 0.16 4ND4-A nrPDB 34 0.16 5X1Y-B nrPDB 34 0.18 4ROS-A nrPDB 34 0.18 2D4A-B nrPDB 34 0.19 2LDB-A nrPDB 34 0.20 5G6R-A nrPDB 33 0.23 3P7M-A nrPDB 33 0.28 6CXS-A nrPDB 33 0.30 1EZ4-A nrPDB 33 0.36 4AJN-A nrPDB 32 0.40 2LDX-A nrPDB 32 0.44 2EW2-A nrPDB 32 0.44 3EUW-A nrPDB 32 0.44 6J9S-A nrPDB 32 0.46 5HTO-A nrPDB 32 0.46 2HQM-A nrPDB 32 0.48 1OC4-A nrPDB 32 0.55 4N3U-A nrPDB 32 0.58 3IWA-A nrPDB 32 0.61 5K0Z-A nrPDB 32 0.64 4TNB-A nrPDB 32 0.64 4J90-A nrPDB 32 0.64 6CEP-A nrPDB 32 0.66 1UXJ-A nrPDB 32 0.69 1YQZ-A nrPDB 32 0.75 1C0L-A nrPDB 32 0.80 1LDM-A nrPDB 31 0.89 3CGD-A nrPDB 31 0.91 4KPR-E nrPDB 31 1.0 3WD7-A nrPDB 31 1.0 3AWJ-A nrPDB 31 1.1 6CMZ-A nrPDB 31 1.1 3Q3C-A nrPDB 31 1.2 4A6N-B nrPDB 31 1.3 5NQB-A nrPDB 31 1.3 3LAD-A nrPDB 31 1.4 1T24-A nrPDB 31 1.4 3GGO-A nrPDB 31 1.6 2G5C-A nrPDB 31 1.6 6DXA-A nrPDB 31 1.6 1SOW-A nrPDB 31 1.7 3DL2-A nrPDB 31 1.9 4L4S-H nrPDB 30 2.0 3C51-A nrPDB 30 2.1 9LDB-A nrPDB 30 2.3 3TJZ-B nrPDB 30 2.4 4WUM-A nrPDB 30 2.6 1EBD-A nrPDB 30 3.1 6N7F-A nrPDB 29 3.4 1ONF-A nrPDB 29 3.6 3AEK-B nrPDB 29 3.7 5BT8-A nrPDB 29 4.6 4KUG-A nrPDB 28 9.4 >3TF5-A nrPDB Length = 493 Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats. Identities = 493/494 (99%), Positives = 493/494 (99%), Gaps = 1/494 (0%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV Sbjct: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS Sbjct: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120 Query: 121 NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180 NGYKIVTEKST PVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI Sbjct: 121 NGYKIVTEKST-PVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 179 Query: 181 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 240 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL Sbjct: 180 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 239 Query: 241 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 300 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW Sbjct: 240 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 299 Query: 301 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 360 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE Sbjct: 300 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 359 Query: 361 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 420 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF Sbjct: 360 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 419 Query: 421 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP 480 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP Sbjct: 420 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP 479 Query: 481 KFSLQDPPNKKPKV 494 KFSLQDPPNKKPKV Sbjct: 480 KFSLQDPPNKKPKV 493 >2O3J-A nrPDB Length = 481 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 303/463 (65%), Positives = 367/463 (79%), Gaps = 6/463 (1%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVE 62 ++ K+ C+GAGYVGGPTC++IAH CP I VTVVD+N ++I WNS LPIYEPGL E+V Sbjct: 8 KVSKVVCVGAGYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLDEIVF 67 Query: 63 SCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNG 122 + RG+NLFFS++I AI EADL+FISVNTPTK YG GKG A DLKY+E+ +R I Q + G Sbjct: 68 AARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMAPDLKYVESVSRTIAQYAGG 127 Query: 123 YKIVTEKSTVPVRAAESIRRIFDANTKPNLN--LQVLSNPEFLAEGTAIKDLKNPDRVLI 180 KIV EKSTVPV+AAESI I K N N QVLSNPEFLAEGTA+KDL NPDRVLI Sbjct: 128 PKIVVEKSTVPVKAAESIGCILREAQKNNENLKFQVLSNPEFLAEGTAMKDLANPDRVLI 187 Query: 181 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 240 GG+ +PEG +AV L +YE+WVPR +I+TTNTWSSELSKL ANAFLAQRISSINSISA+ Sbjct: 188 GGESSPEGLQAVAELVRIYENWVPRNRIITTNTWSSELSKLVANAFLAQRISSINSISAV 247 Query: 241 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 300 CEATGA++ EVA A+G D RIG+KFL+ASVGFGGSCFQKDVL+LVYLCE+LNLP+VA YW Sbjct: 248 CEATGAEISEVAHAVGYDTRIGSKFLQASVGFGGSCFQKDVLSLVYLCESLNLPQVADYW 307 Query: 301 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 360 Q VI++N++QRRRFA +II LFNTVTDKKIAI GFAFKK+TGDTRESS+I++ K+LM+E Sbjct: 308 QGVININNWQRRRFADKIIAELFNTVTDKKIAIFGFAFKKNTGDTRESSAIHVIKHLMEE 367 Query: 361 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 420 A L +YDPKV + Q++ DL+ ++D V RL+T+ DPY A GAHA+V+ TEWD F Sbjct: 368 HAKLSVYDPKVQKSQMLNDLASVTSAQD--VERLITVESDPYAAARGAHAIVVLTEWDEF 425 Query: 421 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIG 463 EL+Y +IH M PA IFDGR +LD L+ IGF+ IG Sbjct: 426 VELNYSQIHNDMQHPAAIFDGRLILD--QKALREIGFRTFAIG 466 >2Y0D-A nrPDB Length = 478 Score = 523 bits (1346), Expect = e-149, Method: Composition-based stats. Identities = 164/481 (34%), Positives = 252/481 (52%), Gaps = 19/481 (3%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 + IG+G VG T + +A + + V +DV++++I+ N+ +PI+EPGLKEV+ Sbjct: 9 MNLTIIGSGKVGLVTGACLADIGHD--VFCLDVDQAKIDILNNGGVPIHEPGLKEVIARN 66 Query: 65 RGKN-LFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGY 123 R L FST+I+ A+ D+ FI+V TP G +ADL+Y+ A AR I + G+ Sbjct: 67 RSAGRLRFSTDIEAAVAHGDVQFIAVGTPPDEDG-----SADLQYVLAAARNIGRYMTGF 121 Query: 124 KIVTEKSTVPVRAAESIRRIFDANTK---PNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180 K++ +KSTVPV AE +R + V+SNPEFL EG A+ D PDR++I Sbjct: 122 KVIVDKSTVPVGTAERVRAAVAEELAKRGGDQMFSVVSNPEFLKEGAAVDDFTRPDRIVI 181 Query: 181 GGDETPEGQRAVQALCAVYEHW-VPREKILTTNTWSSELSKLAANAFLAQRISSINSISA 239 G D+ G+RA + + +Y + E+ L + S+E +K AANA LA RIS +N ++ Sbjct: 182 GCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELAN 241 Query: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299 L + GAD+E V IG D RIG FL A G+GGSCF KDV L+ + + + Sbjct: 242 LADRFGADIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHG--QSLQI 299 Query: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359 + V +N Q+R A +I+ +T + AI G AFK +T D RE+ S + L+ Sbjct: 300 LKAVSSVNATQKRVLADKIVARFGEDLTGRTFAIWGLAFKPNTDDMREAPSRELIAELLS 359 Query: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDM 419 GA + YDP E + +++ ++ D +A A A+VI TEW + Sbjct: 360 RGARIAAYDPVAQEEAR--RVIALDLADHPSWLERLSFVDDEAQAARDADALVIVTEWKI 417 Query: 420 FKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEI 479 FK D+ + ++ K IFDGR + + + G + IG+ S + + +G Sbjct: 418 FKSPDFVALG-RLWKTPVIFDGRNLYE--PETMSEQGIEYHPIGRPGSRQAVAARVTGTA 474 Query: 480 P 480 P Sbjct: 475 P 475 >4A7P-A nrPDB Length = 446 Score = 476 bits (1224), Expect = e-134, Method: Composition-based stats. Identities = 178/463 (38%), Positives = 250/463 (53%), Gaps = 32/463 (6%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES-C 64 +I IG GYVG + + + E V VD + +I + +PIYEPGL +V S Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHE--VVCVDKDARKIELLHQNVMPIYEPGLDALVASNV 67 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 + L F+T++ + +K+AD VFI+V TP++ ADL Y+ A AR I +N Sbjct: 68 KAGRLSFTTDLAEGVKDADAVFIAVGTPSRRG----DGHADLSYVFAAAREIAENLTKPS 123 Query: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184 ++ KSTVPV + + RI A PN +V+SNPEFL EG AI+D K PDRV++G ++ Sbjct: 124 VIVTKSTVPVGTGDEVERII-AEVAPNSGAKVVSNPEFLREGAAIEDFKRPDRVVVGTED 182 Query: 185 TPEGQRAVQALCAVYEHWVPRE--KILTTNTWSSELSKLAANAFLAQRISSINSISALCE 242 + A Q + +Y + +L T +SEL K AANAFLA +I+ IN I+ LCE Sbjct: 183 ----EFARQVMREIYRPLSLNQSAPVLFTGRRTSELIKYAANAFLAVKITFINEIADLCE 238 Query: 243 ATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQ 302 GADV+EV+ IGMD RIG KFL A G+GGSCF KD L L+ P R + Sbjct: 239 QVGADVQEVSRGIGMDNRIGGKFLHAGPGYGGSCFPKDTLALMKTAADNETP--LRIVEA 296 Query: 303 VIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGA 362 + +ND ++R ++I ++ V K + ILG FK +T D R++ S+ I L D GA Sbjct: 297 TVQVNDARKRAMGRKVIKAMGGDVRGKTVGILGLTFKPNTDDMRDAPSLSIIAALQDAGA 356 Query: 363 HLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKE 422 + YDP+ GV + ++ V ++PY A DGA A+VI TEWD F+ Sbjct: 357 TVKAYDPE-------------GVEQASKMLTDVEFVENPYAAADGADALVIVTEWDAFRA 403 Query: 423 LDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKK 465 LD RI K LK + D R + EL+ G Q +GK Sbjct: 404 LDLTRI-KNSLKSPVLVDLRNIYP--PAELERAGLQYTGVGKP 443 >3GG2-A nrPDB Length = 450 Score = 473 bits (1216), Expect = e-134, Method: Composition-based stats. Identities = 148/450 (32%), Positives = 229/450 (50%), Gaps = 31/450 (6%) Query: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLK-EVVESCR 65 I +G GYVG + + A + +R +D + ++I NS T+PIYEPGL+ + + + Sbjct: 5 IAVVGIGYVGLVSATCFAELGANVR--CIDTDRNKIEQLNSGTIPIYEPGLEKMIARNVK 62 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 L F T I+ A+ EAD++FI+V TP G+ +AD+ Y+ AR I + + Y + Sbjct: 63 AGRLRFGTEIEQAVPEADIIFIAVGTPA-----GEDGSADMSYVLDAARSIGRAMSRYIL 117 Query: 126 VTEKSTVPVRAAESIRRIFDANTKPNL---NLQVLSNPEFLAEGTAIKDLKNPDRVLIGG 182 + KSTVPV + IR+ + + SNPEFL EG AI D PDRV++G Sbjct: 118 IVTKSTVPVGSYRLIRKAIQEELDKREVLIDFDIASNPEFLKEGNAIDDFMKPDRVVVGV 177 Query: 183 DETPEGQRAVQALCAVYEHWVPRE-KILTTNTWSSELSKLAANAFLAQRISSINSISALC 241 D RA + + ++Y+ + ++L + S+E++K AANA LA RIS +N ++ LC Sbjct: 178 DSD----RARELITSLYKPMLLNNFRVLFMDIASAEMTKYAANAMLATRISFMNDVANLC 233 Query: 242 EATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQ 301 E GADV V IG D RIG+KFL G+GGSCF KDV L+ E + Sbjct: 234 ERVGADVSMVRLGIGSDSRIGSKFLYPGCGYGGSCFPKDVKALIRTAEDNGYRM--EVLE 291 Query: 302 QVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361 V +N+ Q+ + V + +AI G +FK T D RE+ S+ + + L++ G Sbjct: 292 AVERVNEKQKSILFDKFSTYYKGNVQGRCVAIWGLSFKPGTDDMREAPSLVLIEKLLEVG 351 Query: 362 AHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFK 421 + +YDP +E ++ V + D Y+A GA A+ TEW F+ Sbjct: 352 CRVRVYDPVAMKEA------------QKRLGDKVEYTTDMYDAVRGAEALFHVTEWKEFR 399 Query: 422 ELDYERIHKKMLKPAFIFDGRRVLDGLHNE 451 D+ + + M + + DGR V + + Sbjct: 400 MPDWSALSQAMA-ASLVIDGRNVYELPADS 428 >3VTF-A nrPDB Length = 444 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 139/456 (30%), Positives = 217/456 (47%), Gaps = 40/456 (8%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVV- 61 + + +G GYVG A + RV DVN S + + IYEPGL+E + Sbjct: 20 HMASLSVLGLGYVGVVHAVGFALLGH--RVVGYDVNPSIVERLRAGRPHIYEPGLEEALG 77 Query: 62 ESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQ--- 118 + L F+ + ++A+ D FI+V TP G +ADL+Y+EA AR + + Sbjct: 78 RALSSGRLSFAESAEEAVAATDATFIAVGTPPAPDG-----SADLRYVEAAARAVGRGIR 132 Query: 119 NSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRV 178 + +V KSTVP E + A + V SNPEFL EG+A++D PDR+ Sbjct: 133 AKGRWHLVVVKSTVPPGTTEGLVARAVAEEAGGVKFSVASNPEFLREGSALEDFFKPDRI 192 Query: 179 LIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSIS 238 +IG + +RA L VY+ L +EL K A+N FLA +IS N + Sbjct: 193 VIGAGD----ERAASFLLDVYKAV--DAPKLVMKPREAELVKYASNVFLALKISFANEVG 246 Query: 239 ALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVAR 298 L + G D V A+G+D+RIG + A +GFGGSCF KD L + E+L L Sbjct: 247 LLAKRLGVDTYRVFEAVGLDKRIGRHYFGAGLGFGGSCFPKDTLAFIRFGESLGLEMA-- 304 Query: 299 YWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLM 358 + V+ +N+Y R+A ++++ + + + +LG AFK +T D RES + +++ L+ Sbjct: 305 ISKAVLRVNEY-MPRYAVQLLEERLGGLRGRHVGVLGLAFKPNTDDVRESRGVEVARLLL 363 Query: 359 DEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWD 418 + GA ++++DP + V + VT +DP D V+I T W Sbjct: 364 ERGARVYVHDPMAMEKARAV------------LGDSVTYVEDPQALLDQVEGVIIATAWP 411 Query: 419 MFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQT 454 ++ LDY + + DGR V ++ Sbjct: 412 QYEGLDY--------RGKVVVDGRYVKKAREAKIYE 439 >3G79-A nrPDB Length = 478 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 120/485 (24%), Positives = 207/485 (42%), Gaps = 52/485 (10%) Query: 4 IKKICCIGAGYVGGPTCSVIAHM-CPEIRVTVVDVNES---RINAWNSPTLPIY--EPGL 57 IKKI +G GYVG P + A C E + ++S +I N P+ EPGL Sbjct: 18 IKKIGVLGMGYVGIPAAVLFADAPCFEKVLGFQRNSKSSGYKIEMLNRGESPLKGEEPGL 77 Query: 58 KEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIV 117 +E++ F T I E D V +++ TP + K D + R + Sbjct: 78 EELIGKVVKAGKFECTPDFSRISELDAVTLAIQTP---FANPKDLEPDFSALIDGIRNVG 134 Query: 118 QNSNGYKIVTEKSTV-PVRAAESIRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKN 174 + +V +ST+ P ++I + + K + + PE + G +K+++ Sbjct: 135 KYLKPGMLVVLESTITPGTTEGMAKQILEEESGLKAGEDFALAHAPERVMVGRLLKNIRE 194 Query: 175 PDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSI 234 DR+ +GG + +RAV+ +Y + +++ + ++E++K A N F +I++I Sbjct: 195 HDRI-VGGIDEASTKRAVE----LYSPVLTVGQVIPMSATAAEVTKTAENTFRDLQIAAI 249 Query: 235 NSISALCEATGADVEEVATAIGMDQRIGNKFLK----ASVGFGGSCFQKDVLNL---VYL 287 N ++ CEA G +V +V T + D G + G GG C KD +L V + Sbjct: 250 NQLALYCEAMGINVYDVRTGV--DSLKGEGITRAVLWPGAGVGGHCLTKDTYHLERGVKI 307 Query: 288 CEA-LNLPEVAR----YWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDT 342 L+ PE A ++V D ++ L + K+A+LG+AF KD+ Sbjct: 308 GRGELDYPEGADSIYVLARKVNDFMPAHMYNLTVAALERLGKKMDGSKVAMLGWAFIKDS 367 Query: 343 GDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPY 402 D R + S + GA + ++DP V +++PGV D + +V Sbjct: 368 DDARNTPSEPYRDLCLKAGASVMVHDPYV--------VNYPGVEISDNLEEVV------- 412 Query: 403 EACDGAHAVVICTEWDMFKELDYERIHKKMLKP-AFIFDGRRVLDGLHNELQTIGFQIET 461 A A+V+ + L + K K I DGR V++ +E GF + Sbjct: 413 ---RNADAIVVLAGHSAYSSLKADWAKKVSAKANPVIIDGRNVIE--PDEFIGKGFVYKG 467 Query: 462 IGKKV 466 IG++ Sbjct: 468 IGREG 472 >4XRR-A nrPDB Length = 456 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 121/468 (25%), Positives = 188/468 (40%), Gaps = 37/468 (7%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 K+ GAGYVG TC + V VD + + + + EPGL V Sbjct: 17 KVVIAGAGYVG--TCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLA 74 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 ++ D + AD+V ++V TPT G D + A +I ++ Sbjct: 75 ATGRLTASTSYDPVGAADVVIVTVGTPTDA---GHEMVTD--QLVAACEQIAPRLRAGQL 129 Query: 126 VTEKSTV-PVRAAESIRRIFDANTKPNL-NLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183 V KSTV P + + ++ + + + PE LAEG A+ ++ V+ G Sbjct: 130 VILKSTVSPGTTRTLVAPLLESGGLVHERDFGLAFCPERLAEGVALAQVRTLPVVVGGC- 188 Query: 184 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243 G R+ A + + + + S+E+ KLA N ++ ++ N ++ C Sbjct: 189 ----GPRSAAAAERFWRSALGVDVRQVPSAESAEVVKLATNWWIDANVAIANELARYCAV 244 Query: 244 TGADVEEVATAIGMDQRIGN--KFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQ 301 G DV +V A + + L VG GGSC KD + + + R + Sbjct: 245 LGVDVLDVIGAANTLPKGSSMVNLLLPGVGVGGSCLTKD--PWMAWRDGRDRGVSLRTVE 302 Query: 302 QVIDMNDYQRRRFASRIIDSLFNTVTDK---KIAILGFAFKKDTGDTRESSSIYISKYLM 358 +ND R A+ I D L D+ IA+LG AFK DTGD R + + L Sbjct: 303 TARAVNDDMPRHTAAVIADELVKLGRDRNDTTIAVLGAAFKNDTGDVRNTPVRGVVAALR 362 Query: 359 DEGAHLHIYDPKVPREQIVVDL-SHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEW 417 D G + I+DP +IV + P S D+ VS GA + Sbjct: 363 DSGFRVRIFDPLADPAEIVARFGTAPAASLDEAVS--------------GAGCLAFLAGH 408 Query: 418 DMFKELDYERIHKKMLKPAFIFDGRRVLDGLH-NELQTIGFQIETIGK 464 F ELD+ + +++ +P +FDGR L EL GF IG+ Sbjct: 409 RQFHELDFGALAERVDEPCLVFDGRMHLPPARIRELHRFGFAYRGIGR 456 >4R16-A nrPDB Length = 418 Score = 404 bits (1039), Expect = e-113, Method: Composition-based stats. Identities = 114/467 (24%), Positives = 187/467 (40%), Gaps = 59/467 (12%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 +I +G GY+G PT + A + V D+ I NS I EP + ++ Sbjct: 1 MRIAVLGLGYIGLPTAIMFASSGYD--VVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEV 58 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 T+ + +K +++ I V TP G DL Y+E R + + + Sbjct: 59 LSLGKLKVTDRVEDLKGSNVFIICVQTPLS------GDDPDLSYLERAIRTVAEVMDRGA 112 Query: 125 IVTEKSTVPVRAAESIRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGG 182 +V +ST+P E + R+ + + ++ V PE + G K+L R++ G Sbjct: 113 LVIIESTIPPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172 Query: 183 DETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCE 242 E +A +Y +V + +I TN ++E+ KL N F I+ N + L Sbjct: 173 SE-----KAANLAEKLYRSFV-KGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAH 226 Query: 243 ATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVARYWQ 301 G +V E R+ K +G GG C KD L L E L +AR Sbjct: 227 QYGVNVYEAIELANTHPRV--KIHTPGIGVGGHCLPKDPYLLLSNAKEDFGLIRIARRIN 284 Query: 302 QVIDMNDYQRRRFASRIIDSLFNTVTDKK----IAILGFAFKKDTGDTRESSSIYISKYL 357 + + FA+ ++ K IA+LG A+K T DTR S ++ + + Sbjct: 285 E-------RMPAFAAGLLFEALEKANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFVEII 337 Query: 358 MDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEW 417 + + YDP V D + ++V GA A+VI T+ Sbjct: 338 RNSVKEVRTYDPYVR-------------GTHDSLEKVVE----------GADAIVIATDH 374 Query: 418 DMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464 FK +++E I K M + I DGR ++ + +GF IG+ Sbjct: 375 PEFKSVNWESIGKSM-RHKIIIDGRNII-----KEPPVGFIFRGIGR 415 >3OJO-A nrPDB Length = 431 Score = 386 bits (992), Expect = e-107, Method: Composition-based stats. Identities = 101/444 (22%), Positives = 182/444 (40%), Gaps = 48/444 (10%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 K+ +G GY+G PT + A + V VD+N+ I+ + + I EPGL+EV E Sbjct: 12 SKLTVVGLGYIGLPTSIMFAKHG--VDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEV 69 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSN-GY 123 + +A +D+ I+V TP + R+ D+ + I+ G Sbjct: 70 LSSGKLKVSTTPEA---SDVFIIAVPTPNNDD---QYRSCDISLVMRALDSILPFLKKGN 123 Query: 124 KIVTEKSTVPVRAAESIRRIFDA-NTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGG 182 I+ E + P + ++ + + ++ ++ PE + G +++L + +R++ G Sbjct: 124 TIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGV 183 Query: 183 DETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCE 242 + ++A VY +V E I T+ ++E+SKL N + I+ N ++ +C Sbjct: 184 -----TKACIEAGKRVYRTFVQGEMI-ETDARTAEMSKLMENTYRDVNIALANELTKICN 237 Query: 243 ATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQ 302 +V +V R+ + G GG C D Y A + PE A+ Q Sbjct: 238 NLNINVLDVIEMANKHPRV--NIHQPGPGVGGHCLAVD----PYFIIAKD-PENAKLIQT 290 Query: 303 VIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE-G 361 ++N+ + + ++ K+ + G +K D D RES + I + L E Sbjct: 291 GREINNS-MPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPD 349 Query: 362 AHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFK 421 + YDP V + + D+SH A A V+I ++ FK Sbjct: 350 IEVCAYDPHVELDFVEHDMSH---------------------AVKDASLVLILSDHSEFK 388 Query: 422 ELDYERIHKKMLKPAFIFDGRRVL 445 L K +K IFD + V+ Sbjct: 389 NLSDSHFDK--MKHKVIFDTKNVV 410 >1MV8-A nrPDB Length = 436 Score = 356 bits (912), Expect = 2e-98, Method: Composition-based stats. Identities = 113/430 (26%), Positives = 189/430 (43%), Gaps = 35/430 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 +I G GYVG ++ E V VDV+ ++I+ N PI EPGL+ +++ Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHE--VIGVDVSSTKIDLINQGKSPIVEPGLEALLQQG 58 Query: 65 RGKN-LFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIV----QN 119 R L +T+ A+ ++D+ FI V TP+K G DL YIE R I + Sbjct: 59 RQTGRLSGTTDFKKAVLDSDVSFICVGTPSKKNG-----DLDLGYIETVCREIGFAIREK 113 Query: 120 SNGYKIVTEKSTVPVRAAESIRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDR 177 S + +V + +P + + + + K ++ V +NPEFL E TAIKD P Sbjct: 114 SERHTVVVRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPM 173 Query: 178 VLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSI 237 +IG ++ L +Y I+ +E+ K N + A +++ N I Sbjct: 174 TVIG----ELDKQTGDLLEEIYREL--DAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEI 227 Query: 238 SALCEATGADVEEVATAIGMDQR--IGNKFLKASVGFGGSCFQKDVLNLVYLCEALNL-- 293 + +A G D EV I D + + +++ FGGSC KDV L Y L++ Sbjct: 228 GNIAKAVGVDGREVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEH 287 Query: 294 PEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYI 353 P + + + N Q+ L + +K+ +LG +FK T D RES + + Sbjct: 288 PMLGSLMRS--NSNQVQK-------AFDLITSHDTRKVGLLGLSFKAGTDDLRESPLVEL 338 Query: 354 SKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVI 413 ++ L+ +G L I+D V ++ S+ VS L+ D E + +V+ Sbjct: 339 AEMLIGKGYELRIFDRNVEYARVHGANKEYIESKIPHVSSLL--VSDLDEVVASSDVLVL 396 Query: 414 CTEWDMFKEL 423 ++F +L Sbjct: 397 GNGDELFVDL 406 >3PLN-A nrPDB Length = 424 Score = 338 bits (866), Expect = 3e-93, Method: Composition-based stats. Identities = 106/412 (25%), Positives = 183/412 (44%), Gaps = 34/412 (8%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVE 62 E KI G GYVG +IA V +D+ +++++ N PI + KE+ E Sbjct: 35 EFMKITISGTGYVGLSNGVLIAQ---NHEVVALDIVQAKVDMLNQKISPIVD---KEIQE 88 Query: 63 SCRGKNLFFSTNID--DAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120 K L F D DA + AD V I+ TPT K + +EA R + + Sbjct: 89 YLAEKPLNFRATTDKHDAYRNADYVIIA--TPTDYD--PKTNYFNTSTVEAVIRDVTE-I 143 Query: 121 NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180 N ++ KST+PV I+ ++ V+ +PEFL EG A+ D +P R++I Sbjct: 144 NPNAVMIIKSTIPVGFTRDIKERL------GID-NVIFSPEFLREGRALYDNLHPSRIVI 196 Query: 181 GGDETPEGQRAVQALCA-VYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISA 239 G + + +R L + +P L T++ +E KL AN +LA R++ N + + Sbjct: 197 G-ERSARAERFADLLKEGAIKQDIP---TLFTDSTEAEAIKLFANTYLALRVAYFNELDS 252 Query: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299 E+ G + +++ + +D RIGN + S G+GG C KD L+ E++ +A Sbjct: 253 YAESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIA-- 310 Query: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359 ++D N ++ A I+ K + + K + + R SS I K + Sbjct: 311 --AIVDANRTRKDFIADSILAR-----KPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKA 363 Query: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAV 411 +G + IY+P + ++ ++ Q + ++ ++ E D A V Sbjct: 364 KGIPVIIYEPVMQEDEFFNSRVVRDLNAFKQEADVIISNRMAEELADVADKV 415 >1DLI-A nrPDB Length = 402 Score = 335 bits (858), Expect = 3e-92, Method: Composition-based stats. Identities = 88/376 (23%), Positives = 171/376 (45%), Gaps = 29/376 (7%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI G+GY S+ + + VT+VD+ S+++ N+ PI + ++ + Sbjct: 1 MKIAVAGSGY---VGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYL--- 54 Query: 65 RGKNLFFSTNIDD--AIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNG 122 + K L +D A KEA+LV I+ TPT + D +++E + ++ + N Sbjct: 55 KSKQLSIKATLDSKAAYKEAELVIIA--TPTNY--NSRINYFDTQHVETVIKEVL-SVNS 109 Query: 123 YKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGG 182 + + KST+P+ +R+ F + +++ +PEFL E A+ D P R+++ Sbjct: 110 HATLIIKSTIPIGFITEMRQKFQTD-------RIIFSPEFLRESKALYDNLYPSRIIVSC 162 Query: 183 DE--TPEGQRAVQALCAVYEHWVPRE--KILTTNTWSSELSKLAANAFLAQRISSINSIS 238 +E +P+ + + + + + +L +E KL AN +LA R++ N + Sbjct: 163 EENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELD 222 Query: 239 ALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVAR 298 E+ + + I D RIG + S G+GG C KD L L N+P+ Sbjct: 223 TYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQL--LANYNNIPQT-- 278 Query: 299 YWQQVIDMNDYQRRRFASRIIDSLFNTVTD-KKIAILGFAFKKDTGDTRESSSIYISKYL 357 + ++ N+ ++ A +II+ L + K + + K ++ + RES+ + L Sbjct: 279 LIEAIVSSNNVRKSYIAKQIINVLKEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDIL 338 Query: 358 MDEGAHLHIYDPKVPR 373 + + IY+P + + Sbjct: 339 KSKDIKIIIYEPMLNK 354 >4GBJ-A nrPDB Length = 297 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 47/341 (13%), Positives = 97/341 (28%), Gaps = 55/341 (16%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 KI +G G +G P ++ E + V + S+ + E + + Sbjct: 7 KIAFLGLGNLGTPIAEILLEAGYE--LVVWNRTASKAEPLTKLGATVVENAIDAI----T 60 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 + FS DDA E E + +V+ + Sbjct: 61 PGGIVFSVLADDAAVE----------------------------ELFSMELVEKLGKDGV 92 Query: 126 VTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDET 185 ST+ + + ++ + + + + PE + R +G Sbjct: 93 HVSMSTISPETSRQLAQVHEWYGAHYVGAPIFARPEAV-------------RAKVGNICL 139 Query: 186 PEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATG 245 A + + + E++V + ++ + KLA N +A + + + E G Sbjct: 140 SGNAGAKERIKPIVENFVKGVFDFGDDPGAANVIKLAGNFMIACSLEMMGEAFTMAEKNG 199 Query: 246 ADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVID 305 + + + F G + V L L ++ Q D Sbjct: 200 ISRQSIYEML-----TSTLFAAPIFQNYGKLVASNTYEPVAFRFPLGLKDINLTLQTASD 254 Query: 306 MNDYQRRRFASRIIDSLF-NTVTDKKIAILGFAFKKDTGDT 345 +N FA I + ++ G + D Sbjct: 255 VNAPMP--FADIIRNRFISGLAKGRENLDWGALALGASDDA 293 >1A5Z-A nrPDB Length = 319 Score = 48.3 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 21/152 (13%), Positives = 51/152 (33%), Gaps = 14/152 (9%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI +G G VG T + + ++DV++ R L + + Sbjct: 1 MKIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEG----------DALDLIHGTP 50 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKT-YGMGKGRAADLKYIEACARRIVQNSNGY 123 + +K +D+V ++ P K + + + ++ AR + + + Sbjct: 51 FTRRANIYAGDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDS 110 Query: 124 KIVTEKSTVPVRAAESIRRIFDANTKPNLNLQ 155 ++ + V V ++ ++ P Sbjct: 111 IVIVVTNPVDVLTYFFLK---ESGMDPRKVFG 139 >2HJR-A nrPDB Length = 328 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 43/236 (18%), Positives = 80/236 (33%), Gaps = 40/236 (16%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KKI IGAG +G ++ V + D+ I L + Sbjct: 15 KKISIIGAGQIGSTIALLLGQKDLG-DVYMFDI----IEGVPQGKA----LDLNHCMALI 65 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTY-GMGKGRAADLKYIEACARRIVQN-SNG 122 F N + ++ +D+V I+ P K + K + + A + + N Sbjct: 66 GSPAKIFGENNYEYLQNSDVVIITAGVPRKPNMTRSDLLTVNAKIVGSVAENVGKYCPNA 125 Query: 123 YKIVT------------EKSTVPVRAAESIRRIFDANT-KPNLNLQVLSNPEFLAEGTAI 169 + I EKS +P + + D+ + NL+ + P + Sbjct: 126 FVICITNPLDAMVYYFKEKSGIPANKVCGMSGVLDSARFRCNLSRALGVKPSDV------ 179 Query: 170 KDLKNPDRVLIG--GDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAA 223 +++G GDE +V + +V + KI T++ +E+ K A Sbjct: 180 ------SAIVVGGHGDEMIPLTSSVTIGGILLSDFVEQGKI--THSQINEIIKKTA 227 >1GUZ-A nrPDB Length = 310 Score = 46.0 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 46/127 (36%), Gaps = 11/127 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPT-LPIYEPGLKEVVES 63 KI IGAG VG T +A + ++DV + L +YE G + ++ Sbjct: 1 MKITVIGAGNVGATTAFRLAEKQLARELVLLDV----VEGIPQGKALDMYESGPVGLFDT 56 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAA-DLKYIEACARRIVQNSNG 122 +N +D+V I+ P K + + ++ I+++S Sbjct: 57 -----KVTGSNDYADTANSDIVIITAGLPRKPGMTREDLLMKNAGIVKEVTDNIMKHSKN 111 Query: 123 YKIVTEK 129 I+ Sbjct: 112 PIIIVVS 118 >1GV0-A nrPDB Length = 310 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 47/127 (37%), Gaps = 11/127 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPT-LPIYEPGLKEVVES 63 KI IGAG VG T +A + ++DV + L +YE G + ++ Sbjct: 1 MKITVIGAGNVGATTAFRLAEKQLARELVLLDV----VEGIPQGKALDMYESGPVGLFDT 56 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKG-RAADLKYIEACARRIVQNSNG 122 +N +D+V I+ P K + + + + RI+++S Sbjct: 57 -----KVTGSNDYADTANSDIVVITAGLPRKPGMTREDLLSMNAGIVREVTGRIMEHSKN 111 Query: 123 YKIVTEK 129 IV Sbjct: 112 PIIVVVS 118 >1VPD-A nrPDB Length = 299 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 38/251 (15%), Positives = 82/251 (32%), Gaps = 46/251 (18%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 K+ IG G +G P + + V+ D N E + Sbjct: 6 MKVGFIGLGIMGKPMSKNLLKAGYSLVVS--DRNP-------------------EAIADV 44 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 ++ ++ D++ + + +K + I++ + Sbjct: 45 IAAGAETASTAKAIAEQCDVIITMLP-----------NSPHVKEVALGENGIIEGAKPGT 93 Query: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184 ++ + S++ A+ I A L+ V E AI + V++GGD+ Sbjct: 94 VLIDMSSIAPLASREISDALKAKGVEMLDAPVSGG-----EPKAIDGTLS---VMVGGDK 145 Query: 185 TPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEAT 244 + + A+ V + + ++KLA +A I++++ L Sbjct: 146 -AIFDKYYDLMKAMAGSVVHTG-----DIGAGNVTKLANQVIVALNIAAMSEALTLATKA 199 Query: 245 GADVEEVATAI 255 G + + V AI Sbjct: 200 GVNPDLVYQAI 210 >4DYD-A nrPDB Length = 283 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 8/96 (8%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNS---PTLPIYEPGL 57 M I + +G G +G + VT D+N ++A +YE + Sbjct: 1 MTGITNVTVLGTGVLG--SQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEV 58 Query: 58 KEVVESCRGK---NLFFSTNIDDAIKEADLVFISVN 90 + K + +S ++ A+K+ADLV +V Sbjct: 59 AGAADGAAQKALGGIRYSDDLAQAVKDADLVIEAVP 94 >4PLW-A nrPDB Length = 326 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 48/130 (36%), Gaps = 11/130 (8%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 M + KKI IGAG +GG +IA V + D+ + + Sbjct: 1 MTQRKKISLIGAGNIGGTLAHLIAQKELG-DVVLFDI----VEGMPQGKALDISHSSPIM 55 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKT-YGMGKGRAADLKYIEACARRIVQN 119 + + TN + IK +D+V I+ P K + + K ++ A I + Sbjct: 56 GSNVKITG----TNNYEDIKGSDVVIITAGIPRKPGMSRDDLLSVNAKIMKDVAENIKKY 111 Query: 120 -SNGYKIVTE 128 N + IV Sbjct: 112 CPNAFVIVVT 121 >2BC1-A nrPDB Length = 490 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 13/113 (11%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI------NAWNSPTLPIYEPG 56 +IK++ +GAGY+G V ++DV ++ + + + + E G Sbjct: 193 DIKRVAVVGAGYIGVELAEAFQRKG--KEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHG 250 Query: 57 LK----EVVESCRGKNLFFSTNIDDAIKEADLVFISVN-TPTKTYGMGKGRAA 104 ++ E V+ G D + D+V ++V P T G GK Sbjct: 251 IQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLF 303 >4OM8-A nrPDB Length = 309 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 I+ I IG G +G + +A + V DV + I S L + E L + + Sbjct: 2 IRNIAIIGLGTMGPGMAARLARGGLQ--VVAYDVAPAAIERARS-MLSVAETVLDALGIA 58 Query: 64 CRGKNL---FFSTNIDDAIKEADLVFISVN 90 + F+ +I DA+ ADLV +V Sbjct: 59 LPSAGVGTVRFTDDIGDAVSGADLVIENVP 88 >3PQF-A nrPDB Length = 326 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 34/92 (36%), Gaps = 17/92 (18%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESR----INAWNSPTLPIYEPGLK 58 + K+ IGAG+VG + + + V+DVN+ + + N +P Sbjct: 4 HVNKVALIGAGFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLNHGKAFAPQP--- 60 Query: 59 EVVESCRGKNLFFSTNIDDAIKEADLVFISVN 90 + S + K+AD+V I Sbjct: 61 ----------VKTSYGTYEDCKDADIVCICAG 82 >3HWR-A nrPDB Length = 318 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 53/129 (41%), Gaps = 11/129 (8%) Query: 2 FEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVV 61 F+ K+ +GAG VG ++A E+ + + A + L + E V Sbjct: 17 FQGMKVAIMGAGAVGCYYGGMLARAGHEVILIA---RPQHVQAIEATGLRLETQSFDEQV 73 Query: 62 ESCRGKNLFFSTNIDDAIKEADLVFISV-NTPTKTYGMGKGRAADLKYIEACARRIVQNS 120 + +++ A++ ADLV V +T T++ + A + + V+N+ Sbjct: 74 KVS-------ASSDPSAVQGADLVLFCVKSTDTQSAALAMKPALAKSALVLSLQNGVENA 126 Query: 121 NGYKIVTEK 129 + + + E+ Sbjct: 127 DTLRSLLEQ 135 >5XVH-A nrPDB Length = 306 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 42/253 (16%), Positives = 79/253 (31%), Gaps = 50/253 (19%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 ++ IG G +GGP + + V N T P E Sbjct: 21 MRVGFIGLGIMGGPMATHLLKAGFLAAVY---------NRTREKTKPFAE---------- 61 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 ++ + + D K D+V + V A D++ + +V+ + Sbjct: 62 --AGVYVAESPADLAKRVDVVIVMV-----------SDAPDVEQVLFGPSGVVEGARPGL 108 Query: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184 IV + ST A L+ V + EGT +++GG E Sbjct: 109 IVVDMSTNSPDWARKFAERLAQYGIEFLDAPVTGGQKGAIEGTLT--------IMVGGKE 160 Query: 185 TPEGQRAVQALCAVYEHWVPREK-ILTTNTWS-SELSKLAANAFLAQRISSINSISALCE 242 + + + + I+ + KL +A ++ L + Sbjct: 161 --------ELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQVVVALNTVAMVEGLKLAK 212 Query: 243 ATGADVEEVATAI 255 A G D+++VA + Sbjct: 213 ALGLDMDKVAEVL 225 >5Y8M-A nrPDB Length = 295 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 41/252 (16%), Positives = 81/252 (32%), Gaps = 49/252 (19%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 + I +G G +G P + + V D P + Sbjct: 2 MTTIAFLGLGNMGAPMSANLVGAGH--VVRGFD------------------PAPTAASGA 41 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGY 123 F + +A+ EAD+V + T + + C ++ + Sbjct: 42 AAHGVAVFRS-APEAVAEADVVITMLPT--------------GEVVRRCYTDVLAAARPA 86 Query: 124 KIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183 + + ST+ V A + + +++ L+ V +G A L ++GGD Sbjct: 87 TLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGG----VKGAAAATLAF----MVGGD 138 Query: 184 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243 E+ ++ V E + I + + +K+ N LA + +I L E Sbjct: 139 EST-----LRRARPVLEPMAGK-IIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEK 192 Query: 244 TGADVEEVATAI 255 G + + I Sbjct: 193 LGLSAQSLFDVI 204 >1HYH-A nrPDB Length = 309 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 48/138 (34%), Gaps = 14/138 (10%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 +KI IG G VG + +D NE+++ A ++ + + Sbjct: 2 RKIGIIGLGNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQID--------FQDAMANL 53 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNT-PTKTYGMGKGRAADLKYIEACARRIVQNSNG- 122 N A+ +AD+V ++ + R A+LK+ + + + N Sbjct: 54 EAHG-NIVINDWAALADADVVISTLGNIKLQQDNPTGDRFAELKFTSSMVQSVGTNLKES 112 Query: 123 ---YKIVTEKSTVPVRAA 137 +V + V V A Sbjct: 113 GFHGVLVVISNPVDVITA 130 >5A9T-A nrPDB Length = 290 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 41/244 (16%), Positives = 77/244 (31%), Gaps = 55/244 (22%) Query: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66 + G G +G + + ++ V WN PG Sbjct: 8 VTVAGLGPMGSALAAALLDRGHDVTV------------WNRS------PGKAA---PLVA 46 Query: 67 KNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIV 126 K + +I DA+ + L+ + + AD + + + G +V Sbjct: 47 KGARQADDIVDAVSASRLLVVCL--------------ADYDALYSALGPAREALRGRVVV 92 Query: 127 TEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPE--------FLAEGTA--IKDLKNP- 175 S P A E++R + + L+ ++ P FL G+A ++ K Sbjct: 93 NLNSGTPKEANEALRWA-ERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETL 151 Query: 176 ----DRVLIGGDETPEGQRAVQALCAVYEHWVP----REKILTTNTWSSELSKLAANAFL 227 D V +G + L +Y + + ++E +KLA + FL Sbjct: 152 AGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFL 211 Query: 228 AQRI 231 I Sbjct: 212 PAVI 215 >1HYE-A nrPDB Length = 313 Score = 38.3 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 12/172 (6%) Query: 5 KKICCIGA-GYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 K+ IGA G VG T ++A + ++ E IN IY+ + + Sbjct: 1 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIG-REHSINKLEGLREDIYD----ALAGT 55 Query: 64 CRGKNLFFSTNIDDAI-KEADLVFISVNTPTKTYGMGKGRA-ADLKYIEACARRIVQNSN 121 N++ ++ + I E+D+V I+ P K A + K + A++I + + Sbjct: 56 RSDANIYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEICD 115 Query: 122 GYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLK 173 V T PV + + D+ + N + ++ + L AI Sbjct: 116 TKIFVI---TNPVDVMTY-KALVDSKFERNQVFGLGTHLDSLRFKVAIAKFF 163 >3TL2-A nrPDB Length = 315 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 51/135 (37%), Gaps = 18/135 (13%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDV----NESRINAWNSPTLPIYEPGLKEV 60 KK+ IGAG+ G T ++A V +VD+ N ++ A + L+ Sbjct: 9 KKVSVIGAGFTGATTAFLLAQKEL-ADVVLVDIPQLENPTKGKALDM---------LEAS 58 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACA-RRIVQN 119 N+ +++ D ++D+V I+ K A I R I ++ Sbjct: 59 PVQGFDANIIGTSDYADT-ADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKH 117 Query: 120 SNGYKIVTEKSTVPV 134 S IV T PV Sbjct: 118 SPNAIIVVL--TNPV 130 >3NEP-X nrPDB Length = 314 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 46/138 (33%), Gaps = 17/138 (12%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVN----ESRINAWNSPTLPIYEPGLKEV 60 K+ IGAG VG +A V +VD+ + + + PI+ G Sbjct: 1 MKVTVIGAGNVGATVAECVARQDVAKEVVMVDIKDGMPQGKALDMRE-SSPIH--GFDTR 57 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKT-YGMGKGRAADLKYIEACARRIVQN 119 V TN +++D+ I+ P A + + + + V+ Sbjct: 58 V---------TGTNDYGPTEDSDVCIITAGLPRSPGMSRDDLLAKNTEIVGGVTEQFVEG 108 Query: 120 SNGYKIVTEKSTVPVRAA 137 S I+ + + V Sbjct: 109 SPDSTIIVVANPLDVMTY 126 >4WLE-A nrPDB Length = 340 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 39/190 (20%), Positives = 65/190 (34%), Gaps = 27/190 (14%) Query: 5 KKICCIGA-GYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 K+ +GA G +G P ++ + R+T+ D+ + P L + Sbjct: 27 AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT----------PGVAADLSHIETK 76 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADL------KYIEACARRIV 117 K + D +K D+V I P K GM + + ACA+ Sbjct: 77 AAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKP-GMTRDDLFNTNATIVATLTAACAQHCP 135 Query: 118 QNSNGYKIVTEKSTVPVRAAESIRRIFDANTK--PNLNLQVLSNPEFLAEGTAIKDLKNP 175 + ST+P+ A + K L ++ F+AE + P Sbjct: 136 EAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLD----P 191 Query: 176 DRV---LIGG 182 RV +IGG Sbjct: 192 ARVNVPVIGG 201 >4PLF-A nrPDB Length = 334 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 41/125 (32%), Gaps = 11/125 (8%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 M + KKI IG+G +GG + A V + DV + L Sbjct: 5 MTKRKKISLIGSGMIGGTMAYLCAQKELG-DVVLFDV----VKNMPQGKA----LDLSHS 55 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAAD--LKYIEACARRIVQ 118 TN + IK +D+V I+ K + D L + R + + Sbjct: 56 SSIADTNVKVTGTNSYEDIKGSDVVIITAGLTKAPGKSDKEWSRDDLLPFNAKIMREVGE 115 Query: 119 NSNGY 123 N Y Sbjct: 116 NIKKY 120 >6ACQ-A nrPDB Length = 302 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 40/242 (16%), Positives = 76/242 (31%), Gaps = 40/242 (16%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINA----WNSPTLPIYEPG-L 57 +KK+C IGAG +G A E V + D+ + ++ N + + G + Sbjct: 20 HMKKVCVIGAGTMGSGIAQAFAAKGFE--VVLRDIKDEFVDRGLDFINKNLSKLVKKGKI 77 Query: 58 KEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIV 117 +E + + + +++ A + DLV + + + K ADL Sbjct: 78 EEATKVEILTRISGTVDLNMA-ADCDLVIEAA---VERMDIKKQIFADL----------- 122 Query: 118 QNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAE----------GT 167 N + + +T + E + ++ NP + + Sbjct: 123 DNICKPETILASNTSSLSITEVASATKRPDKVIGMHF---FNPAPVMKLVEVIRGIATSQ 179 Query: 168 AIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREK-ILTTNTWSSE----LSKLA 222 D + IG D + + + + IL S E KL Sbjct: 180 ETFDAVKETSIAIGKDPVEVAEAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLG 239 Query: 223 AN 224 AN Sbjct: 240 AN 241 >6H9S-A nrPDB Length = 307 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 41/131 (31%), Gaps = 13/131 (9%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI IG G VG T + + + + D+N+ L + + Sbjct: 1 MKISIIGTGRVGSSTAFALINAAVADEIVLYDLNKEMAEG----------EALDLLHATT 50 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAA-DLKYIEACARRIVQNSNGY 123 K + I+ +D+V I+ K + K I+ + I + Sbjct: 51 FHKRMIIRAGEYSDIEGSDIVLITAGAAQKPGETRLDLTIKNAKIIKGISENIKKY--AP 108 Query: 124 KIVTEKSTVPV 134 + T PV Sbjct: 109 NTLIINITNPV 119 >1NHQ-A nrPDB Length = 447 Score = 37.1 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 37/106 (34%), Gaps = 18/106 (16%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI-------------NAWNSPT 49 E+ + IG+GY+G A +VTV+D+ + + + Sbjct: 148 EVNNVVVIGSGYIGIEAAEAFAKAG--KKVTVIDILDRPLGVYLDKEFTDVLTEEMEANN 205 Query: 50 LPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKT 95 + I E VE G D +ADLV ++V T Sbjct: 206 ITI---ATGETVERYEGDGRVQKVVTDKNAYDADLVVVAVGVRPNT 248 >5ER0-A nrPDB Length = 518 Score = 36.7 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 38/120 (31%), Gaps = 13/120 (10%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI---------NAWNSP-TLPI 52 E K+I IGAGY+G + + VT++D + + Sbjct: 196 EAKRITVIGAGYIGAELAEAYSTTGHD--VTLIDAMARVMPKYFDADFTDVIEQDYRDHG 253 Query: 53 YEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVN-TPTKTYGMGKGRAADLKYIEA 111 + L E VES + D E DL + + P GK A I Sbjct: 254 VQLALGETVESFTDSATGLTIKTDKNSYETDLAILCIGFRPNTDLLKGKVDMAPNGAIIT 313 >5JE8-A nrPDB Length = 302 Score = 35.9 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 37/254 (14%), Positives = 88/254 (34%), Gaps = 45/254 (17%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 +KKI IG G +G P + V VD+N KE S Sbjct: 7 MKKIGFIGLGNMGLPMSKNLVKSGY--TVYGVDLN-------------------KEAEAS 45 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGY 123 + +I + D+VF S+ +P ++ + A + +N + Sbjct: 46 FEKEGGIIGLSISKLAETCDVVFTSLPSPRA-----------VEAVYFGAEGLFENGHSN 94 Query: 124 KIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183 + + STV + +++ +A + ++ L+ P ++ G + + ++ G Sbjct: 95 VVFIDTSTVSPQLN---KQLEEAAKEKKVDF--LAAP--VSGGVIGAENRTLTFMVGGSK 147 Query: 184 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243 + +++ V + + + KL N + + ++ L + Sbjct: 148 D---VYEKTESIMGVLGANIFHVSEQIDSGTT---VKLINNLLIGFYTAGVSEALTLAKK 201 Query: 244 TGADVEEVATAIGM 257 D++++ + + Sbjct: 202 NNMDLDKMFDILNV 215 >1Y6J-A nrPDB Length = 318 Score = 35.6 bits (80), Expect = 0.046, Method: Composition-based stats. Identities = 20/144 (13%), Positives = 46/144 (31%), Gaps = 21/144 (14%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESR----INAWNSPTLPIYEPGLKEV 60 K+ IGAG+VG +A + ++DV + + N + Sbjct: 8 SKVAIIGAGFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFM-------- 59 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRA-ADLKYIEACARRIVQN 119 + +K+ D++ ++ K A ++ + + I++ Sbjct: 60 ------GQMSLYAGDYSDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKY 113 Query: 120 SNGYKIVTEKSTVPVRAAESIRRI 143 N I+ + PV + + Sbjct: 114 YNHGVILVVSN--PVDIITYMIQK 135 >6IHE-A nrPDB Length = 303 Score = 35.6 bits (80), Expect = 0.046, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 37/121 (30%), Gaps = 8/121 (6%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 K+ IGAG +G + D+ + +E L+ + Sbjct: 1 AKVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPELPDK--------FEHELRHAFATK 52 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 K TN D + D+V IS P K + D I + + + N Sbjct: 53 GIKANVLGTNSLDDVSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKLPSKNPGA 112 Query: 125 I 125 I Sbjct: 113 I 113 >1PZF-A nrPDB Length = 331 Score = 35.6 bits (80), Expect = 0.051, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 50/166 (30%), Gaps = 33/166 (19%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KK+ IG+G +GG + A V + DV + V S Sbjct: 10 KKVAMIGSGMIGGTMGYLCALREL-ADVVLYDVVKGMPEGKALDLSH---------VTSV 59 Query: 65 RGKNLFFST--NIDDAIKEADLVFISVN---TPTKTYGMGKGRAADLKYIEACARRIVQN 119 N+ + + A+ AD V ++ P K L + R I QN Sbjct: 60 VDTNVSVRAEYSYEAALTGADCVIVTAGLTKVPGKPDSEWSRNDL-LPFNSKIIREIGQN 118 Query: 120 SNGY-----------------KIVTEKSTVPVRAAESIRRIFDANT 148 Y K++ E S VP + + D+ Sbjct: 119 IKKYCPKTFIIVVTNPLDCMVKVMCEASGVPTNMICGMACMLDSGR 164 >4YWO-A nrPDB Length = 462 Score = 35.6 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 49/262 (18%), Positives = 82/262 (31%), Gaps = 37/262 (14%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEP-GLKEVVE 62 + K+ IG G G + + + N +P + E+ + Sbjct: 15 MHKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTC--VNVGCVPSKRMLYIAEIYK 72 Query: 63 SCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQ---N 119 R + +E D + V KT D++ I+ AR I Sbjct: 73 KAREVTGSEVYPPFSSFQEKDGL---VQEMRKTKYEDLLSYYDVELIQGEARFISPHAVK 129 Query: 120 SNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLN-LQVLSNPEFLAEGTAIKDLKNPDRV 178 NG I EK + ++ I RI P L+ + +N E L+ I L Sbjct: 130 VNGQVIEAEKFVIATGSSPLIPRI------PGLDKVGFWTNREALSPDRRIDSLA----- 178 Query: 179 LIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTW---SSELSKLAANAFLAQRISSIN 235 +IGG + + V + R +L + S E ++ N Sbjct: 179 VIGGRALALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMEN----------- 227 Query: 236 SISALCEATGADVEEVATAIGM 257 + TG +V+EV G Sbjct: 228 --DGVAVVTGVNVKEVRKGAGK 247 >1MLD-A nrPDB Length = 314 Score = 35.6 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 62/190 (32%), Gaps = 27/190 (14%) Query: 5 KKICCIGA-GYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 K+ +GA G +G P ++ + R+T+ D+ + P L + Sbjct: 1 AKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT----------PGVAADLSHIETR 50 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQN---S 120 K + D +K D+V I P K GM + + Sbjct: 51 ATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKP-GMTRDDLFNTNATIVATLTAACAQHCP 109 Query: 121 NGYKIVT---EKSTVPVRAAESIRRIFDANTK--PNLNLQVLSNPEFLAEGTAIKDLKNP 175 + + ST+P+ A + K L ++ F+AE + P Sbjct: 110 DAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLD----P 165 Query: 176 DRV---LIGG 182 RV +IGG Sbjct: 166 ARVSVPVIGG 175 >2CFY-A nrPDB Length = 521 Score = 35.6 bits (80), Expect = 0.058, Method: Composition-based stats. Identities = 47/312 (15%), Positives = 95/312 (30%), Gaps = 51/312 (16%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI--NAWNSPTLPIYEPGLKEVVES 63 K +GA YV +A + ++ V V + + N + E G+K + + Sbjct: 214 KTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 273 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKY-IEACARRIVQNSNG 122 K ++ ++ +T ++ G+ L +AC R+I + G Sbjct: 274 VPIKVEQIEAGTPGRLR-----VVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 328 Query: 123 YKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVL--- 179 KI + +PV E + L +V P + G + + Sbjct: 329 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 388 Query: 180 ----------------IGGDETPEGQRAVQALCAVYEH-WVPREKILTTNTWSSELSKLA 222 G E ++ + VY + P E + + + +K+ Sbjct: 389 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKII 448 Query: 223 ANAFLAQRISSINSISALCEAT----------GADVEEVATAIGMDQ------------- 259 N +R+ + + G +++ + IG+ Sbjct: 449 CNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTK 508 Query: 260 RIGNKFLKASVG 271 R G L+A G Sbjct: 509 RSGASILQAGCG 520 >5AYV-A nrPDB Length = 309 Score = 35.6 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 35/85 (41%), Gaps = 12/85 (14%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 +I +GAG +G +++A ++ + +++A N L ++ G +E Sbjct: 1 MRIYVLGAGSIGSLFGALLARAGNDVTLIG---RREQVDAINKNGLHVF--GAEEFTVKP 55 Query: 65 RGKNLFFSTNIDDAIKEADLVFISV 89 + I + DL+ ++V Sbjct: 56 KA-------TIYAPEEPPDLLILAV 73 >1DXL-A nrPDB Length = 470 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 47/286 (16%), Positives = 94/286 (32%), Gaps = 38/286 (13%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVT--VVDVNESRINAWN-SPTLPIYEPGLKEVV 61 KK+ IGAGY+G SV + E+ V ++ + + + G+K + Sbjct: 178 KKLVVIGAGYIGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQGMKFKL 237 Query: 62 E----------SCRGKNLFFSTNIDDAIKEADLVFISVN-TPTKTYGMGKGRAADLKYIE 110 + + S + I EAD+V +S TP + + + Sbjct: 238 KTKVVGVDTSGDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVETDKLG 297 Query: 111 ACARRIVQNSNGYKIVTEKSTVPVRA------AESIRRI-FDANTKPNLNLQ-----VLS 158 ++N + +P + + + + A +++ V + Sbjct: 298 RILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEYLAGKVGHVDYDKVPGVVYT 357 Query: 159 NPEFLAEGTAIKDLKNPD---RVLIGGDETPEGQRAVQALCAVYEHWVPREK-----ILT 210 NPE + G + +K RV +A+ + + +E + Sbjct: 358 NPEVASVGKTEEQVKETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAEKETDKILGVHI 417 Query: 211 TNTWSSELSKLAANAFLAQRI-SSINSISALCEATGADVEEVATAI 255 + EL AA +A + +S I+ +C A E + A Sbjct: 418 MAPNAGELIHEAA---IALQYDASSEDIARVCHAHPTMSEAIKEAA 460 >5JFC-L nrPDB Length = 474 Score = 34.8 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 39/98 (39%), Gaps = 10/98 (10%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KK+ IGAG G + +A M E+ + + + P + + +K+ +E+ Sbjct: 155 KKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLIYGIPEFRLPKEIVKKELENL 214 Query: 65 RGKNLFFST--------NIDDAIKEADLVFISV--NTP 92 R + T ++ +E D +FI TP Sbjct: 215 RRLGVKIETNVLVGKTITFEELREEYDAIFIGTGAGTP 252 >4UEJ-A nrPDB Length = 346 Score = 34.8 bits (78), Expect = 0.099, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 59/187 (31%), Gaps = 20/187 (10%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNS-------PTLPIYEP 55 E K + IGAG +G + VT +D++ ++ S + + P Sbjct: 160 ENKNVIIIGAGTIGLLAIQCAVALGA-KSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 Query: 56 GLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARR 115 ++ V+ R L T + + + + + P + DL A Sbjct: 219 QMQSVLRELRFNQLILET---AGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSA---T 272 Query: 116 IVQNSNGYKIVT-----EKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIK 170 + V S P + E+ R+ K +L + F + A++ Sbjct: 273 FGKILRKELTVIGSWMNYSSPWPGQEWETASRLL-TERKLSLEPLIAHRGSFESFAQAVR 331 Query: 171 DLKNPDR 177 D+ Sbjct: 332 DIARNAM 338 >3ZZN-A nrPDB Length = 310 Score = 34.8 bits (78), Expect = 0.100, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNE 39 K+ +G+G VG T +A + V +VD++ Sbjct: 1 MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDR 35 >3L8K-A nrPDB Length = 466 Score = 34.4 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 43/286 (15%), Positives = 96/286 (33%), Gaps = 49/286 (17%) Query: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66 + IGAGY+G S+ M + + I + + + + + + S Sbjct: 175 MVIIGAGYIGLEIASIFRLMGVQTHI---------IEMLDRALITLEDQDIVNTLLSILK 225 Query: 67 KNLFFSTNIDD--AIKEADLVFISVNTPTKTYGMGKGRAADLKYIEAC---------ARR 115 N+ F++ + + IK+ + I + G K + + A AR Sbjct: 226 LNIKFNSPVTEVKKIKDDEYEVIY----STKDGSKKSIFTN-SVVLAAGRRPVIPEGARE 280 Query: 116 IVQNSNGYKIVTE---KSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIK-- 170 I + + IV + K+ +P A + + + + +A G + Sbjct: 281 IGLSISKTGIVVDETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNIMANGMPVDYV 340 Query: 171 DLKN--------PDRVLIGGDETPEGQRAVQALCAVY--------EHWVPREKILTTNTW 214 D+K+ P +G + + ++ + A Y + + +E +L Sbjct: 341 DVKSIPVTIYTIPSLSYVGILPSKARKMGIEIVEAEYNMEEDVSAQIYGQKEGVLKLIFE 400 Query: 215 SSELSKLAANAFLAQRISS-INSISALCEATGADVEEVATAIGMDQ 259 + +L + IN + L A G + +++A+ Sbjct: 401 RGSM-RLIGAWMIGVHSQYLINELG-LAVAYGLNAKQLASFAEQHP 444 >3WSV-A nrPDB Length = 322 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 19/39 (48%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRIN 43 +K+ +G G+VG + + + ++DVN+ + Sbjct: 6 RKVVIVGTGFVGTSIAYAMINQGVANELVLIDVNQEKAE 44 >5U8W-A nrPDB Length = 481 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 54/304 (17%), Positives = 104/304 (34%), Gaps = 50/304 (16%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KK+ IGAG +G SV A + E+ V + A + E KE ++ Sbjct: 185 KKLGVIGAGVIGLELGSVWARLGAEVTV---------LEALDKFLPAADEQIAKEALKVL 235 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARR--------- 115 + L + + +++ V T T T G+ + K I A RR Sbjct: 236 TKQGLNIR--LGARVTASEVKKKQV-TVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAA 292 Query: 116 ---IVQNSNGYKIVTE--KSTVPVRAA--ESIRRIFDANTKPNLNLQVLSNPEFLAEGTA 168 + + G+ V + K++VP A + +R A+ + V E +A A Sbjct: 293 DSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVA---ERIAGHKA 349 Query: 169 IKDLK--------NPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSK 220 + +P+ +G E V+ + + + + N + L K Sbjct: 350 QMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTF-PFAASGRAMAANDTTG-LVK 407 Query: 221 LAANAFLAQRIS------SINSI---SALCEATGADVEEVATAIGMDQRIGNKFLKASVG 271 + A+A + + S + A+ G E++ + + +A++ Sbjct: 408 VIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALA 467 Query: 272 FGGS 275 G Sbjct: 468 VNGH 471 >5VJ7-A nrPDB Length = 476 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 40/105 (38%), Gaps = 10/105 (9%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KK+ IGAG G + +A M E+ + + + P + + L++ ++ Sbjct: 155 KKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLTYGIPEFRLPKEILRKELKKL 214 Query: 65 RGKNLFFSTN--------IDDAIKEADLVFISV--NTPTKTYGMG 99 + T+ I + ++E D VFI TP G Sbjct: 215 SLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPKLPNIPG 259 >4LN1-A nrPDB Length = 336 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 29/92 (31%), Gaps = 9/92 (9%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 I ++ +G G VG + + +VDVNE++ Sbjct: 27 INRVVLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAV---------P 77 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKT 95 + K+ADLV I+ P K Sbjct: 78 FAPAPTRVWKGSYEDCKDADLVVITAGLPQKP 109 >3GVH-A nrPDB Length = 324 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 41/124 (33%), Gaps = 14/124 (11%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 KI IG+G +GG + V + D+ E GL S Sbjct: 9 KIALIGSGMIGGTLAHLAGLKELG-DVVLFDIAEGT----PQGK------GLDIAESSPV 57 Query: 66 GK--NLFFSTNIDDAIKEADLVFISVNTPTKT-YGMGKGRAADLKYIEACARRIVQNSNG 122 F N AI+ AD+V ++ P K +LK +E I + + Sbjct: 58 DGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPE 117 Query: 123 YKIV 126 ++ Sbjct: 118 AFVI 121 >2R9Z-A nrPDB Length = 463 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 33/226 (14%), Positives = 65/226 (28%), Gaps = 43/226 (19%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVD----------VNESRINAWNSPTLPIYE 54 K++ IGAGY+G ++ E+ V ++ ++ + ++ + E Sbjct: 167 KRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGI---E 223 Query: 55 PGLKEVVESCR--GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEAC 112 L+ V + + ++ D V +V T +G +EA Sbjct: 224 THLEFAVAALERDAQGTTLVAQDGTRLEGFDSVIWAVGRAPNTRDLG---------LEAA 274 Query: 113 ARRIVQNSNGYKIVTEKSTVPV----RAAESIRRIFDANTKPNLNLQVLSNPEFLAEG-- 166 + N + + VP ++ L E L +G Sbjct: 275 GIEVQSNGMVPTDAYQNTNVPGVYALGDITGRDQLTPVAIAAGRRLA-----ERLFDGQS 329 Query: 167 --TAIKD------LKNPDRVLIGGDETPEGQRAVQALCAVYEHWVP 204 D +P +G E +R L + P Sbjct: 330 ERKLDYDNIPTVVFAHPPLSKVGLSEPEARERLGDVLTVYETSFTP 375 >4ND4-A nrPDB Length = 321 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 46/130 (35%), Gaps = 11/130 (8%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60 M E +KI IG+G +GG ++ V + D+ E + Sbjct: 1 MIERRKIAVIGSGQIGGNIAYIVGKDNL-ADVVLFDIAEG----IPQGKA----LDITHS 51 Query: 61 VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKT-YGMGKGRAADLKYIEACARRIVQN 119 + + TN I +D+V I+ + P + + + + +++ A + + Sbjct: 52 MVMFGSTSKVIGTNDYADISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKY 111 Query: 120 -SNGYKIVTE 128 N + I Sbjct: 112 CPNAFVICIT 121 >5X1Y-B nrPDB Length = 554 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 37/104 (35%), Gaps = 11/104 (10%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRV------TVVDVNESRIN-----AWNSPTLPIY 53 K++ IG+GY+G + H+ EI + + + + + Sbjct: 250 KRLTVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLVK 309 Query: 54 EPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYG 97 + V +S K ++ + N + E+D + ++ T Sbjct: 310 GATFERVEQSGEIKRVYVTVNGSREVIESDQLLVATGRKPNTDS 353 >4ROS-A nrPDB Length = 320 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 38/115 (33%), Gaps = 10/115 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI IGAG +GG + V + D+ ++ + E Sbjct: 4 SKIALIGAGQIGGTLAHLAGLKELG-DVVLFDI----VDGVPQGKA----LDIAESAPVD 54 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGR-AADLKYIEACARRIVQ 118 + + AI AD+V ++ P K +LK +EA I + Sbjct: 55 GFDAKYSGASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGAGIKE 109 >2D4A-B nrPDB Length = 308 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 20/135 (14%), Positives = 42/135 (31%), Gaps = 12/135 (8%) Query: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66 I +GAG VG T ++ + + + L Sbjct: 2 ITILGAGKVGMATAVMLMMRGYDDLLLIART---------PGKPQGEALDLAHAAAELGV 52 Query: 67 KNLFFSTNIDDAIKEADLVFISVNTPTKT-YGMGKGRAADLKYIEACARRIVQNSNGYKI 125 +N + ++ +D+V ++ K + A+ + A +I + + Sbjct: 53 DIRISGSNSYEDMRGSDIVLVTAGIGRKPGMTREQLLEANANTMADLAEKIKAYAKDAIV 112 Query: 126 VTEKSTVPVRAAESI 140 V +T PV A + Sbjct: 113 VI--TTNPVDAMTYV 125 >2LDB-A nrPDB Length = 317 Score = 33.6 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 54/134 (40%), Gaps = 18/134 (13%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI--NAWNSPTLPIYEPGLKEVVE 62 ++ IGAG+VG + + + ++D NES+ +A + ++ P Sbjct: 7 ARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAP------- 59 Query: 63 SCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS-- 120 K + D ++ADLV I + G + D A R IV++ Sbjct: 60 ----KPVDIWHGDYDDCRDADLVVICAGA-NQKPGETRLDLVDKN--IAIFRSIVESVMA 112 Query: 121 NGYKIVTEKSTVPV 134 +G++ + +T PV Sbjct: 113 SGFQGLFLVATNPV 126 >5G6R-A nrPDB Length = 295 Score = 33.2 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 38/129 (29%), Gaps = 35/129 (27%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 K I G G +G + + V N + +P+ E G K Sbjct: 3 KHIGIFGLGAMGTALAAKYLEHGYKTSVW---------NRTTAKAIPLVEQGAK------ 47 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124 ++ I + + DL+ I + + + +E R +Q Sbjct: 48 ------LASTISEGVNANDLIIICL--------------LNNQVVEDALRDALQTLPSKT 87 Query: 125 IVTEKSTVP 133 IV + P Sbjct: 88 IVNLTNGTP 96 >3P7M-A nrPDB Length = 321 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 19/96 (19%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNES-----RINAWNSPTLPIYEPGLKE 59 KKI +GAG +GG + A + V + D+ + ++ T PI + Sbjct: 6 KKITLVGAGNIGGTLAHL-ALIKQLGDVVLFDIAQGMPNGKALDLLQ--TCPI-----EG 57 Query: 60 VVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKT 95 V RG TN ++ +D+V ++ P K Sbjct: 58 VDFKVRG------TNDYKDLENSDVVIVTAGVPRKP 87 >6CXS-A nrPDB Length = 602 Score = 32.9 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 46/158 (29%), Gaps = 35/158 (22%) Query: 223 ANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVL 282 AN+F I L + G V I +G + GFGG ++D Sbjct: 328 ANSFRTSHYPYSEEIMRLADREGIVV------IDETPAVGLHLNFMATGFGGDAPKRDTW 381 Query: 283 NLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDT 342 + EA R ++++ + + + A + D+ Sbjct: 382 KEIGTKEAHE-----RILRELVSRDKNHP------------------CVVMWSVANEPDS 418 Query: 343 GDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDL 380 + + L+ L DP+ +V L Sbjct: 419 D---SEGAKEYFEPLIKLTKEL---DPQKRPVTVVTYL 450 >1EZ4-A nrPDB Length = 318 Score = 32.9 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 34/93 (36%), Gaps = 14/93 (15%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDV--NESRINAWNSPTLPIYEPGLKEVVE 62 +K+ +G G VG +A +VDV + ++ +A + L++ Sbjct: 6 QKVVLVGDGAVGSSYAFAMAQQGIAEEFVIVDVVKDRTKGDALD----------LEDA-- 53 Query: 63 SCRGKNLFFSTNIDDAIKEADLVFISVNTPTKT 95 + K+ADLV I+ P K Sbjct: 54 QAFTAPKKIYSGEYSDCKDADLVVITAGAPQKP 86 >4AJN-A nrPDB Length = 331 Score = 32.5 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 27/89 (30%), Gaps = 17/89 (19%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRIN----AWNSPTLPIYEPGLKEVV 61 KI +G G VG I + +VDV E ++ +L + P Sbjct: 21 KITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTP------ 74 Query: 62 ESCRGKNLFFSTNIDDAIKEADLVFISVN 90 S+ + LV I+ Sbjct: 75 -------KIVSSKDYSVTANSKLVIITAG 96 >2LDX-A nrPDB Length = 331 Score = 32.5 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 15/37 (40%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI 42 KI +G G VG I + +VD + ++ Sbjct: 21 KITVVGVGDVGMACAISILLKGLADELALVDADTDKL 57 >2EW2-A nrPDB Length = 316 Score = 32.5 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 6/82 (7%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI GAG +G ++ VT++D + I A L I + +EVV + Sbjct: 4 MKIAIAGAGAMGSRLGIMLHQGG--NDVTLIDQWPAHIEAIRKNGL-IADFNGEEVVANL 60 Query: 65 RGKNLFFSTNIDDAIKEADLVF 86 +F ID ++ DL+ Sbjct: 61 ---PIFSPEEIDHQNEQVDLII 79 >3EUW-A nrPDB Length = 344 Score = 32.5 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 40/247 (16%), Positives = 78/247 (31%), Gaps = 51/247 (20%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 +I GAG +G + IA P++ + V I +P ++ Sbjct: 6 RIALFGAGRIGHVHAANIAAN-PDLELVV-----------------IADPFIEGAQRLAE 47 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125 + D+ D+ I + +PT T+ RA +E + + Sbjct: 48 ANGAEAVASPDEVFARDDIDGIVIGSPTSTHVDLITRA-----VERGIPALCEK------ 96 Query: 126 VTEKSTVPVRAAESIRRIFDANTKPN-----LNLQVLSNPEFLAEGT--AIKDLKNPDR- 177 P+ + R L +P F A A +++ N ++ Sbjct: 97 -------PIDLDIEMVRACKEKIGDGASKVMLGFNRRFDPSFAAINARVANQEIGNLEQL 149 Query: 178 VLIGGDETPEGQRAVQALCAVYEHWVPRE----KILTTNTWSSELSKLAANAFLAQRISS 233 V+I D P + + ++ + + N E++ AN F +Q I+ Sbjct: 150 VIISRDPAPAPKDYIAGSGGIFRDMTIHDLDMARFFVPNI--VEVTATGANVF-SQEIAE 206 Query: 234 INSISAL 240 N + Sbjct: 207 FNDYDQV 213 >6J9S-A nrPDB Length = 326 Score = 32.5 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 38/197 (19%), Positives = 66/197 (33%), Gaps = 44/197 (22%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDV--NESRINAWN-SPTLPIYEPGLKEVV 61 +K+ +G G VG + + +VD+ ++++ +A + LP P Sbjct: 10 QKVILVGDGAVGSSYAYAMVLQGIAQEIGIVDIFKDKTKGDAIDLEDALPFTSP------ 63 Query: 62 ESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSN 121 +S DA K+ADLV I+ P K E + +N Sbjct: 64 ------KKIYSAEYSDA-KDADLVVITAGAPQKPG-------------ETRLDLVNKNLK 103 Query: 122 GYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIG 181 KS V I D+ N V +NP + K P ++G Sbjct: 104 -----ILKSIV--------DPIVDSGF--NGIFLVAANPVDILTYATWKLSGFPKNRVVG 148 Query: 182 GDETPEGQRAVQALCAV 198 + + R Q++ + Sbjct: 149 SGTSLDTARFRQSIAKM 165 >5HTO-A nrPDB Length = 346 Score = 32.5 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 33/100 (33%), Gaps = 9/100 (9%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 KI +G+G +GG ++I V + DV + +C+ Sbjct: 36 KIVLVGSGMIGGVMATLIVQKNLG-DVVMFDV----VKNMPQGKALDTSHSNVMAYSNCK 90 Query: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAAD 105 +N D +K AD+V ++ K D Sbjct: 91 VTG----SNSYDDLKGADVVIVTAGFTKAPGKSDKEWNRD 126 >2HQM-A nrPDB Length = 479 Score = 32.5 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 32/226 (14%), Positives = 67/226 (29%), Gaps = 46/226 (20%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVV-DVNESRINAWNSPTL--PIYEPGLK--- 58 KK+ +GAGY+G V + E + + + + + T+ + G+ Sbjct: 186 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 245 Query: 59 -----EVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACA 113 +V ++ L N +I + D + ++ ++ + Sbjct: 246 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRK--------------SHLGMGS 291 Query: 114 RRIVQNSNGYKIVT----EKSTVP--------VRAAESIRRIFDANTKPNLNLQVLSNPE 161 + N + + + + VP V E A K + L PE Sbjct: 292 ENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLS---NRLFGPE 348 Query: 162 FLAEGTAIKD------LKNPDRVLIGGDETPEGQRAVQALCAVYEH 201 + +P+ IG E ++ + VY Sbjct: 349 KFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNS 394 >1OC4-A nrPDB Length = 322 Score = 32.1 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 34/101 (33%), Gaps = 9/101 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI +G+G +GG ++I V + D+ + +C Sbjct: 5 AKIVLVGSGMIGGVMATLIVQKNLG-DVVMFDI----VKNMPHGKALDTSHTNVMAYSNC 59 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAAD 105 + +N D +K+AD+V ++ K D Sbjct: 60 KVSG----SNTYDDLKDADVVIVTAGFTKAPGKSDKEWNRD 96 >4N3U-A nrPDB Length = 159 Score = 32.1 bits (71), Expect = 0.58, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 19/68 (27%) Query: 277 FQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGF 336 D+ Y +P N Y A+ + K I+G Sbjct: 43 LPSDIGPFPYHVHEKPVPASKNCSATENHFNPYNGTVRAATPAAHEVGDLAGKHGNIMGE 102 Query: 337 AFKKDTGD 344 ++K + D Sbjct: 103 SYKTEYDD 110 >3IWA-A nrPDB Length = 472 Score = 32.1 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 36/115 (31%), Gaps = 13/115 (11%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHM-CPEIRVTVVD-------VNESRINAWNSPTLP--- 51 E+ K +G G++G +A M + V + ++S Sbjct: 158 EVSKAVIVGGGFIGLEMAVSLADMWGIDTTVVELADQIMPGFTSKSLSQMLRHDLEKNDV 217 Query: 52 IYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVN-TPTKTYGMGKGRAAD 105 + G ++VV D +ADLV ++ +P G D Sbjct: 218 VVHTG-EKVVRLEGENGKVARVITDKRTLDADLVILAAGVSPNTQLARDAGLELD 271 >5K0Z-A nrPDB Length = 331 Score = 32.1 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 16/38 (42%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRIN 43 KI +G G VG I + +VDV E ++ Sbjct: 21 KITVVGVGQVGMACAISILGKGLCDELALVDVLEDKLK 58 >4TNB-A nrPDB Length = 590 Score = 32.1 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 30/88 (34%), Gaps = 2/88 (2%) Query: 360 EGAHLHIYDPKVPREQIVVD--LSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEW 417 G + +V R + + SH E + +++ Sbjct: 386 RGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEEAAEVKRH 445 Query: 418 DMFKELDYERIHKKMLKPAFIFDGRRVL 445 F+ ++++R+ ML P F+ D R V Sbjct: 446 PFFRNMNFKRLEAGMLDPPFVPDPRAVY 473 >4J90-A nrPDB Length = 222 Score = 32.1 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 13/86 (15%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 K+ IG G GG C + M E V VD+NE ++NA+ S V+ + Sbjct: 7 KQFAVIGLGRFGGSICKELHRMGHE--VLAVDINEEKVNAYASYATH-------AVIANA 57 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVN 90 +N S I+ + V +++ Sbjct: 58 TEENELLSL----GIRNFEYVIVAIG 79 >6CEP-A nrPDB Length = 334 Score = 31.7 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 4/56 (7%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRIN----AWNSPTLPIYEPGL 57 KI +G G VG I + +VDV E ++ +L + P + Sbjct: 23 KITVVGVGQVGMACAISILGKSLTDELALVDVLEDKLKGEMMDLQHGSLFLQTPKI 78 >1UXJ-A nrPDB Length = 309 Score = 31.7 bits (70), Expect = 0.69, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 40/124 (32%), Gaps = 11/124 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPT-LPIYEPGLKEVVES 63 KKI IGAG+VG T +A + ++D+ + L +YE E Sbjct: 3 KKISIIGAGFVGSTTAHWLAAKELG-DIVLLDI----VEGVPQGKALDLYEASPIEGF-D 56 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGY 123 R TN +D++ ++ P K + I + Sbjct: 57 VRVTG----TNNYADTANSDVIVVTSGAPRKPGMSREDLIKVNADITRACISQAAPLSPN 112 Query: 124 KIVT 127 ++ Sbjct: 113 AVII 116 >1YQZ-A nrPDB Length = 438 Score = 31.7 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 40/114 (35%), Gaps = 17/114 (14%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPE----------IRVTVVDVNESRINAWNSPTLPI 52 ++ K+ +GAGYV + ++ D+N+ ++ + +P Sbjct: 147 QVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPY 206 Query: 53 YEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNT-PTKTYGMGKGRAAD 105 L E + + G + F + ++ D++ V T P + D Sbjct: 207 R---LNEEINAINGNEITFKS---GKVEHYDMIIEGVGTHPNSKFIESSNIKLD 254 >1C0L-A nrPDB Length = 363 Score = 31.7 bits (70), Expect = 0.80, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 18/37 (48%) Query: 1 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDV 37 M K++ +G+G +G + ++A + + D+ Sbjct: 3 MHSQKRVVVLGSGVIGLSSALILARKGYSVHILARDL 39 >1LDM-A nrPDB Length = 329 Score = 31.3 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 16/38 (42%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRIN 43 KI +G G VG I V +VDV E ++ Sbjct: 22 KITVVGVGAVGMACAISILMKDLADEVALVDVMEDKLK 59 >3CGD-A nrPDB Length = 480 Score = 31.3 bits (69), Expect = 0.91, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 39/102 (38%), Gaps = 9/102 (8%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRV--------TVVDVNESRINAWNSPTLPIYE 54 +++ + IG G +G + ++R+ T+ D + + + I E Sbjct: 185 KVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHI-E 243 Query: 55 PGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTY 96 E V++ +G + D +ADLV +SV T Sbjct: 244 ILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTD 285 >4KPR-E nrPDB Length = 499 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 61/185 (32%), Gaps = 34/185 (18%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRI--NAWNSPTLPIYEPGLK----- 58 K +GA YV +A + ++ V V + + N + E G+K Sbjct: 192 KTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQF 251 Query: 59 -----EVVESCRGKNLFFS---TNIDDAIK-EADLVFISVNTPTKTYGMGKGRAADLKYI 109 E +E+ L + TN ++ I+ E + V ++V Sbjct: 252 VPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGR------------------ 293 Query: 110 EACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAI 169 ++C R I + G KI + +PV E + L ++ P + G + Sbjct: 294 DSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLL 353 Query: 170 KDLKN 174 Sbjct: 354 AQRLY 358 >3WD7-A nrPDB Length = 403 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 38/108 (35%), Gaps = 12/108 (11%) Query: 80 KEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAES 139 E ++++T T + + D + + + + +K++ EKS + R Sbjct: 25 AEGLATILAISTATPPNCVIQADYPDYYFGITNSEHMTELKEKFKLLCEKSMIRKRHMCL 84 Query: 140 IRRIFDAN----------TKPNLNLQVLSNPEFLAEG--TAIKDLKNP 175 I AN ++ ++ P+ E AIK+ P Sbjct: 85 TEEILKANPNMCLYMGTSLDARQDISLVEVPKLGKEAATKAIKEWGQP 132 >3AWJ-A nrPDB Length = 402 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 35/108 (32%), Gaps = 12/108 (11%) Query: 80 KEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAES 139 + +++ T T + D + + ++ + +KS + R Sbjct: 26 PDGPATILAIGTSNPTNIFEQSTYPDFFFDVTNCNDKTELKKKFQRICDKSGIKKRHFHL 85 Query: 140 IRRIF----------DANTKPNLNLQVLSNPEFLAEG--TAIKDLKNP 175 I +A+ P ++ VL P+ E +AIK P Sbjct: 86 TDEILRKNPSICKFKEASLDPRQDIAVLEVPKLAKEAAISAIKQWGQP 133 >6CMZ-A nrPDB Length = 466 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 15/29 (51%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVT 33 K++ +GAGY+G V + ++ V Sbjct: 179 KRLVVVGAGYIGLELGIVYRKLGVDVSVV 207 >3Q3C-A nrPDB Length = 299 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 51/153 (33%), Gaps = 32/153 (20%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 +K+I IG G++G P + + + V D+ +S ++ Sbjct: 2 MKQIAFIGLGHMGAPMATNLLKAGYLLNVF--DLVQSAVDGL------------------ 41 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGY 123 + + DA++ AD+V + P + G D ++ + Sbjct: 42 -VAAGASAARSARDAVQGADVVISML--PASQHVEGLYLDDD---------GLLAHIAPG 89 Query: 124 KIVTEKSTVPVRAAESIRRIFDANTKPNLNLQV 156 +V E ST+ +A I L+ V Sbjct: 90 TLVLECSTIAPTSARKIHAAARERGLAMLDAPV 122 >4A6N-B nrPDB Length = 398 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 39/110 (35%), Gaps = 6/110 (5%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 K + IG G VG ++ ++ V D + TL +++ +E ++ Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDRE--ARIFGGTLDLHKGSGQEAMKKA 84 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNT----PTKTYGMGKGRAADLKYIE 110 ++ + + AD ++T P + + DL+ I Sbjct: 85 GLLQTYYDLALPMGVNIADEKGNILSTKNVKPENRFDNPEINRNDLRAIL 134 >5NQB-A nrPDB Length = 332 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 28/91 (30%), Gaps = 21/91 (23%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 KI +G G VG I + +VDV E + LK + + Sbjct: 22 KITVVGVGAVGMACAISILMKDLADELALVDVMEDK---------------LKGEMMDLQ 66 Query: 66 GKNLFFSTN------IDDAIKEADLVFISVN 90 +LF T + LV I+ Sbjct: 67 HGSLFLRTPKIVSGKDYSVTANSKLVIITAG 97 >3LAD-A nrPDB Length = 476 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 45/298 (15%), Positives = 99/298 (33%), Gaps = 40/298 (13%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVT-VVDVNESRINAWNSPTLP--IYEPGLKEVVE 62 K+ IGAG +G SV A + E+ V +D ++ + + + GLK ++ Sbjct: 182 KLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLG 241 Query: 63 --------SCRGKNLFFSTNIDDAIKEADLVFISVN---TPTKTYGMGKGRAADLK---Y 108 + + F + + D + ++V T G D + Y Sbjct: 242 ARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIY 301 Query: 109 IEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFD--ANTKPNLNLQVLSNPEFLAEG 166 ++ V V + + +A+E + + A K +N ++ P + Sbjct: 302 VDDYCATSVPGVYAIGDVVRGAMLAHKASEEGVVVAERIAGHKAQMNYDLI--PAVI--- 356 Query: 167 TAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAF 226 +P+ +G E V V+ + + + N ++ K+ A+A Sbjct: 357 -----YTHPEIAGVGKTEQALKAEGVAINVGVF-PFAASGRAMAAN-DTAGFVKVIADAK 409 Query: 227 LAQRIS------SINSI---SALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGS 275 + + S + A+ G E++ + + +A++ G Sbjct: 410 TDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGH 467 >1T24-A nrPDB Length = 322 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 32/101 (31%), Gaps = 9/101 (8%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KI +G+G +GG ++I V + D+ + +C Sbjct: 5 AKIVLVGSGMIGGVMATLIVQKNLG-DVVLFDI----VKNMPHGKALDTSHTNVMAYSNC 59 Query: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAAD 105 + +N D + AD+V ++ K D Sbjct: 60 KVSG----SNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRD 96 >3GGO-A nrPDB Length = 314 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 19/41 (46%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINA 44 ++ + +G G++GG + + ++ D+N I+ Sbjct: 33 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISK 73 >2G5C-A nrPDB Length = 281 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 19/41 (46%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINA 44 ++ + +G G++GG + + ++ D+N I+ Sbjct: 1 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISK 41 >6DXA-A nrPDB Length = 396 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 16/108 (14%), Positives = 35/108 (32%), Gaps = 12/108 (11%) Query: 80 KEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAES 139 + +++ T T + + D + + + + ++ + +KS + R Sbjct: 18 ADGPATILAIGTATPPNAVDQSSYPDYYFKITNSEHMTELKEKFRRMCDKSAIKKRYMYL 77 Query: 140 IRRIFDANTK----------PNLNLQVLSNPEFLAE--GTAIKDLKNP 175 I N K ++ V+ P E AIK+ P Sbjct: 78 TEEILKENPKVCEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQP 125 >1SOW-A nrPDB Length = 328 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 41/123 (33%), Gaps = 15/123 (12%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESC 64 KKI IG+G +GG + V + DV +P + S Sbjct: 9 KKIAMIGSGMIGGTMGYLCVLREL-ADVVLFDVVTG---------MPEGKALDDSQATSI 58 Query: 65 RGKNLFFST-NIDDAIKEADLVFISVN---TPTKTYGMGKGRAADLKYIEACARRIVQNS 120 N+ ++ N + I +D+V I+ P K+ L + R + Q Sbjct: 59 ADTNVSVTSANQYEKIAGSDVVIITAGLTKVPGKSDKEWSRNDL-LPFNAKIIREVAQGV 117 Query: 121 NGY 123 Y Sbjct: 118 KKY 120 >3DL2-A nrPDB Length = 303 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESR 41 + KI +G G +G I+ R+ ++D++E Sbjct: 14 VNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGT 51 >4L4S-H nrPDB Length = 339 Score = 30.2 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 29/91 (31%), Gaps = 21/91 (23%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65 KI +G G VG I + +VDV E + LK + + Sbjct: 21 KITVVGVGAVGMACAISILMKDLADELALVDVIEDK---------------LKGEMMDLQ 65 Query: 66 GKNLFFSTN------IDDAIKEADLVFISVN 90 +LF T + + LV I+ Sbjct: 66 HGSLFLRTPKIVSGKDYNVTANSKLVIITAG 96 >3C51-A nrPDB Length = 543 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 16/29 (55%) Query: 417 WDMFKELDYERIHKKMLKPAFIFDGRRVL 445 +F+++ + ++ ML P F+ D R V Sbjct: 449 HPLFRDISWRQLEAGMLTPPFVPDSRTVY 477 >9LDB-A nrPDB Length = 332 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 4/56 (7%) Query: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRIN----AWNSPTLPIYEPGL 57 KI +G G VG I + +VDV E ++ +L + P + Sbjct: 22 KITVVGVGAVGMACAISILMKELADEIALVDVMEDKLKGEMMDLQHGSLFLRTPKI 77 >3TJZ-B nrPDB Length = 355 Score = 30.2 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 16/117 (13%), Positives = 31/117 (26%), Gaps = 13/117 (11%) Query: 341 DTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKD 400 D +R+S + + + +Y+ IV VS L Sbjct: 242 DEDGSRDSPLFDFIESCLRNKHEMVVYE---AASAIVNLPGCSAKELAPAVSVLQLFCSS 298 Query: 401 PYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGF 457 P A A + L+ + A D ++ + + T+ Sbjct: 299 PKAALRYA----------AVRTLNKVAMKHPSAVTACNLDLENLVTDANRSIATLAI 345 >4WUM-A nrPDB Length = 389 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 35/108 (32%), Gaps = 12/108 (11%) Query: 80 KEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAES 139 E +++ T T + + D + + V+ +K + EKS + R Sbjct: 13 AEGPAAILAIGTATPPNAIEQSEYPDYYFRVTNSEDKVELKEKFKRMCEKSMIKKRYLYL 72 Query: 140 IRRIFDAN----------TKPNLNLQVLSNPEFLAEG--TAIKDLKNP 175 I N ++ V+ P+ E AIK+ P Sbjct: 73 TEDILKENPNVCAYMATSLDARQDMVVVEVPKLGKEAATRAIKEWGQP 120 >1EBD-A nrPDB Length = 455 Score = 29.8 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 15/108 (13%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLK----EV 60 K + IG GY+G + A+ +VT+++ ++ + I + LK EV Sbjct: 171 KSLVVIGGGYIGIELGTAYANFG--TKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEV 228 Query: 61 VESCRGKNLFFSTN----IDDAIKE-----ADLVFISVNTPTKTYGMG 99 V + K + +A E AD V ++V T +G Sbjct: 229 VTNALAKGAEEREDGVTVTYEANGETKTIDADYVLVTVGRRPNTDELG 276 >6N7F-A nrPDB Length = 453 Score = 29.4 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 42/242 (17%), Positives = 76/242 (31%), Gaps = 37/242 (15%) Query: 5 KKICCIGAGYVGGPTCSVIAHMCPEIRVTV------VDVNESRINAW------NSPTLPI 52 K+ +GAGY+ V+ + + + + +++ ++ N P L Sbjct: 171 KRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHT 230 Query: 53 YEPGLKEVVESCRGKNLFFSTNIDDAIK-EADLVFISVNTPTKTYGMGKGRAA----DLK 107 + EV + + + + + D + E D + ++ G + D Sbjct: 231 H----AEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKG 286 Query: 108 YIEACARRIVQNSNGYKI--VTEK-STVPVRAA---ESIRRIFDANTKPNLNLQVLSNPE 161 YIE A Y + V K + PV A R+F+ T L+ Q Sbjct: 287 YIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQ------ 340 Query: 162 FLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKL 221 A +P +G E ++ Q Y+ TN L KL Sbjct: 341 ----NVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKL 396 Query: 222 AA 223 Sbjct: 397 VT 398 >1ONF-A nrPDB Length = 500 Score = 29.4 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 35/105 (33%), Gaps = 10/105 (9%) Query: 3 EIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDV------NESRINAWNSPT----LPI 52 E KKI +G+GY+ +VI + + + +ES IN + + I Sbjct: 175 ESKKIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINI 234 Query: 53 YEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYG 97 ++ KNL + + D V V T Sbjct: 235 VTFADVVEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTEN 279 >3AEK-B nrPDB Length = 525 Score = 29.4 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 44/143 (30%), Gaps = 18/143 (12%) Query: 343 GDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPY 402 D R L ++ +Y P+ V V ++D Sbjct: 197 DDLR---------KLGQAHFNVLMY-PETGESAARHLERACKQPFTKIVPIGVGATRDFL 246 Query: 403 EACDGAHAVVICTEWDMFKELDYER-IHKKMLKPAFIF---DGRRVLDGLHNELQTIGFQ 458 + + T+ ++ + + L +F DG V+ + +GF+ Sbjct: 247 AEVSKITGLPVVTDESTLRQPWWSASVDSTYLTGKRVFIFGDGTHVIAAARIAAKEVGFE 306 Query: 459 IETIG---KKVSSK-RIPYAPSG 477 + +G ++++ R A G Sbjct: 307 VVGMGCYNREMARPLRTAAAEYG 329 >5BT8-A nrPDB Length = 403 Score = 29.0 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 31/83 (37%), Gaps = 4/83 (4%) Query: 342 TGDTRESSSIYISKYLMDEGAHLHIYD----PKVPREQIVVDLSHPGVSEDDQVSRLVTI 397 T D R +++ K +++GA + ++ P + L+ + + + V + Sbjct: 40 TSDARLRAALPTIKAALEKGAAVMVFSHLGRPVEGEPKPEQSLAPVAAYLTEALGQEVKL 99 Query: 398 SKDPYEACDGAHAVVICTEWDMF 420 D + + V+ E F Sbjct: 100 FTDYLDGVEVEAGQVVLLENVRF 122 >4KUG-A nrPDB Length = 290 Score = 28.2 bits (61), Expect = 9.4, Method: Composition-based stats. Identities = 50/261 (19%), Positives = 77/261 (29%), Gaps = 55/261 (21%) Query: 4 IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63 +KK+ +GAG +G A V V D+ E ++ G+ + +S Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKG--CEVIVRDIKEEFVDR-----------GIATITKS 47 Query: 64 CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSN-- 121 L I +A KE L IS T K DL +EA + Sbjct: 48 LSK--LVAKEKITEADKEEILSRISGTTDMKLAA-----DCDL-VVEAAIENMKIKKEIF 99 Query: 122 -------GYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKN 174 + + +T + E A+ ++ NP + Sbjct: 100 AELDGICKPETILASNTSSLSITEVASATKRADKVIGMHF---FNP---------APVMK 147 Query: 175 PDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSI 234 V+ G + E AV+ + E I T +E N L I I Sbjct: 148 LVEVIRGAATSQETFDAVKEMS---------ESIGKTPVEVAEAPGFVVNRIL---IPMI 195 Query: 235 NSISALCEATGADVEEVATAI 255 N + G EE A Sbjct: 196 NE-ATFILQEGVAKEEDIDAA 215 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.122 0.302 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,611,515 Number of Sequences: 36641 Number of extensions: 594659 Number of successful extensions: 2382 Number of sequences better than 10.0: 119 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 2134 Number of HSP's gapped (non-prelim): 157 length of query: 494 length of database: 10,336,785 effective HSP length: 101 effective length of query: 393 effective length of database: 6,636,044 effective search space: 2607965292 effective search space used: 2607965292 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)