BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O60341 (852 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5L3D-A nrPDB 1751 0.0 3ABT-A nrPDB 1380 0.0 2COM-A nrPDB 238 1e-62 2L3D-A nrPDB 214 1e-55 4FWE-A nrPDB 207 1e-53 5IT3-A nrPDB 186 3e-47 3L1R-A nrPDB 114 2e-25 3BI4-A nrPDB 64 2e-10 1O5W-A nrPDB 61 2e-09 2BXR-A nrPDB 60 4e-09 1REO-A nrPDB 54 3e-07 2BK5-A nrPDB 53 6e-07 3RHA-A nrPDB 52 1e-06 3KVE-A nrPDB 51 2e-06 1SEZ-A nrPDB 51 2e-06 4IV9-A nrPDB 50 5e-06 1F8S-A nrPDB 50 6e-06 2JB2-A nrPDB 48 2e-05 2VVL-G nrPDB 47 3e-05 6CR0-A nrPDB 47 4e-05 4DGK-A nrPDB 47 5e-05 3LOV-A nrPDB 47 5e-05 2IVE-A nrPDB 46 7e-05 3I6D-A nrPDB 45 1e-04 5MOG-A nrPDB 42 0.001 4ZCC-A nrPDB 42 0.002 3KYB-A nrPDB 40 0.004 3NK2-X nrPDB 40 0.005 3KKJ-A nrPDB 40 0.006 3K30-A nrPDB 39 0.009 3LXD-A nrPDB 39 0.010 5GJK-A nrPDB 39 0.012 4YRY-B nrPDB 39 0.013 5NMX-A nrPDB 38 0.022 5VJ7-A nrPDB 37 0.034 5JFC-L nrPDB 37 0.043 5TUK-A nrPDB 36 0.091 3X0V-A nrPDB 35 0.12 3RFW-A nrPDB 35 0.13 1I8T-A nrPDB 35 0.15 2TMD-A nrPDB 35 0.19 3WE0-A nrPDB 34 0.23 4IVM-B nrPDB 34 0.32 4EMJ-A nrPDB 34 0.34 5TUF-A nrPDB 33 0.36 2YVV-A nrPDB 33 0.59 4HAM-A nrPDB 33 0.61 4AP1-A nrPDB 33 0.62 2DCE-A nrPDB 33 0.65 4OVI-A nrPDB 32 1.1 3RP7-A nrPDB 32 1.1 4UIR-A nrPDB 32 1.5 3FXA-A nrPDB 32 1.5 2FQ3-A nrPDB 32 1.6 2R9Z-A nrPDB 32 1.7 2E5V-A nrPDB 31 1.8 3CF4-A nrPDB 31 1.9 5J5Z-A nrPDB 31 2.0 5TUM-A nrPDB 31 2.1 4TNS-A nrPDB 31 2.1 5YGQ-A nrPDB 31 2.2 6IUM-B nrPDB 31 2.4 5Z70-A nrPDB 31 2.8 3GMC-A nrPDB 31 2.9 4U85-A nrPDB 31 3.0 3UP5-A nrPDB 30 3.0 2D0I-A nrPDB 30 3.0 1PS9-A nrPDB 30 3.6 4FNP-A nrPDB 30 3.7 5T0C-AD nrPDB 30 3.9 3JYJ-A nrPDB 30 4.0 3MJ4-A nrPDB 30 4.0 4REP-A nrPDB 30 4.1 1V59-A nrPDB 30 4.1 4A6N-B nrPDB 30 4.5 5ZBC-A nrPDB 30 5.0 5ER0-A nrPDB 30 5.1 3LAD-A nrPDB 30 5.1 2LCK-A nrPDB 30 5.2 5MJK-A nrPDB 30 5.4 3ULK-A nrPDB 30 5.4 1ZCN-A nrPDB 30 5.4 2VOU-A nrPDB 30 5.6 5JCN-A nrPDB 30 6.1 4K22-A nrPDB 30 6.3 3EJB-B nrPDB 30 6.4 5BR7-A nrPDB 30 6.5 5CIO-A nrPDB 29 7.1 5ZYN-B nrPDB 29 7.9 6AHD-N nrPDB 29 8.1 6FTJ-1 nrPDB 29 8.3 4Y4M-A nrPDB 29 9.0 2QA2-A nrPDB 29 9.6 1X14-A nrPDB 29 9.7 >5L3D-A nrPDB Length = 852 Score = 1751 bits (4536), Expect = 0.0, Method: Compositional matrix adjust. Identities = 851/852 (99%), Positives = 852/852 (100%) Query: 1 MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTP 60 MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTP Sbjct: 1 MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTP 60 Query: 61 RKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEY 120 RKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEY Sbjct: 61 RKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEY 120 Query: 121 REMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQ 180 REMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQ Sbjct: 121 REMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQ 180 Query: 181 SRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEA 240 SRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEA Sbjct: 181 SRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEA 240 Query: 241 PYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSF 300 PYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSF Sbjct: 241 PYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSF 300 Query: 301 GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKC 360 GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKC Sbjct: 301 GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKC 360 Query: 361 PLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQE 420 PLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQE Sbjct: 361 PLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQE 420 Query: 421 KHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLV 480 KHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLV Sbjct: 421 KHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLV 480 Query: 481 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN 540 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN Sbjct: 481 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN 540 Query: 541 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGC 600 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGC Sbjct: 541 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGC 600 Query: 601 EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLN 660 EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLN Sbjct: 601 EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLN 660 Query: 661 KVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD 720 KVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD Sbjct: 661 KVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD 720 Query: 721 DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPI 780 DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGS+SYVAAGSSGNDYDLMAQPI Sbjct: 721 DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSHSYVAAGSSGNDYDLMAQPI 780 Query: 781 TPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQA 840 TPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQA Sbjct: 781 TPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQA 840 Query: 841 TPGVPAQQSPSM 852 TPGVPAQQSPSM Sbjct: 841 TPGVPAQQSPSM 852 >3ABT-A nrPDB Length = 662 Score = 1380 bits (3573), Expect = 0.0, Method: Compositional matrix adjust. Identities = 662/662 (100%), Positives = 662/662 (100%) Query: 172 SGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTF 231 SGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTF Sbjct: 1 SGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTF 60 Query: 232 EATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGL 291 EATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGL Sbjct: 61 EATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGL 120 Query: 292 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM 351 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM Sbjct: 121 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM 180 Query: 352 ELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQA 411 ELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQA Sbjct: 181 ELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQA 240 Query: 412 LEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPP 471 LEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPP Sbjct: 241 LEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPP 300 Query: 472 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDW 531 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDW Sbjct: 301 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDW 360 Query: 532 HFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR 591 HFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR Sbjct: 361 HFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR 420 Query: 592 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV 651 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV Sbjct: 421 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV 480 Query: 652 QRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEA 711 QRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEA Sbjct: 481 QRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEA 540 Query: 712 AGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN 771 AGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN Sbjct: 541 AGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN 600 Query: 772 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG 831 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG Sbjct: 601 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG 660 Query: 832 AM 833 AM Sbjct: 661 AM 662 >2COM-A nrPDB Length = 124 Score = 238 bits (606), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 112/114 (98%), Positives = 112/114 (98%) Query: 166 SEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNP 225 S EEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNP Sbjct: 5 SSGEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNP 64 Query: 226 KIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTG 279 KIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTG Sbjct: 65 KIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTG 118 >2L3D-A nrPDB Length = 102 Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 100/101 (99%), Positives = 100/101 (99%) Query: 173 GVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFE 232 VEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFE Sbjct: 2 SVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFE 61 Query: 233 ATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPL 273 ATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPL Sbjct: 62 ATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPL 102 >4FWE-A nrPDB Length = 796 Score = 207 bits (528), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 123/332 (37%), Positives = 184/332 (55%), Gaps = 29/332 (8%) Query: 504 LEEKLQELEAN--PPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDF-EF 560 L EK++E+ S + S + Q+L +H +NLE+A + L +S + WD ++ F +F Sbjct: 483 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 542 Query: 561 TGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDA 620 G H + GYS + LAEGLDI+L + V+ + Y SG EV T T Y Sbjct: 543 AGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDY--SGDEVQVTTTDGTG----YSAQK 596 Query: 621 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSV---NL 677 VL T+PL +L Q A+QF PPL E K A+ +G G + K+ L F FWD V + Sbjct: 597 VLVTVPLALL--QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 654 Query: 678 FGHVGSTTASRGELFLFWNL---YKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGI 734 FGHV + + RG +F+++ K +L++++AGEA + + D ++ +C+A L+ + Sbjct: 655 FGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLREL 714 Query: 735 FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIP 794 F VP P + V+RW DPW + +YS+V G SG YD++A+ I Sbjct: 715 FKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQ------------G 762 Query: 795 RLFFAGEHTIRNYPATVHGALLSGLREAGRIA 826 +FFAGE T R++P TV GA LSG+REA +IA Sbjct: 763 TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 794 Score = 89.4 bits (220), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 20/255 (7%) Query: 186 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 243 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 261 DVMELDELYEFPEYSRDP----TMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 316 Query: 244 SDTVL-VHRVHSYLERHGLINFGIYK---RIKPLPTKKTGK-VIIIGSGVSGLAAARQLQ 298 V V R+ ++ R GLIN G+ LP K VIIIG+G +GLAAARQL Sbjct: 317 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLH 376 Query: 299 SFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKI 356 +FG+ VT+LEA+DR+GGRV + KG V GA +V G NP+A++ +Q+ + + K Sbjct: 377 NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGR-GAQIVNGCINNPVALMCEQLGISMHKF 435 Query: 357 KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVI 416 ++C L + G+ D+ ++ FN LL+ S + D L + P LG+ +E + Sbjct: 436 GERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS--EWRKDKTQLQDVP--LGEKIEEIY 491 Query: 417 Q--LQEKHVKDEQIE 429 + ++E ++ ++E Sbjct: 492 KAFIKESGIQFSELE 506 >5IT3-A nrPDB Length = 85 Score = 186 bits (473), Expect = 3e-47, Method: Composition-based stats. Identities = 85/85 (100%), Positives = 85/85 (100%) Query: 183 LPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPY 242 LPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPY Sbjct: 1 LPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPY 60 Query: 243 NSDTVLVHRVHSYLERHGLINFGIY 267 NSDTVLVHRVHSYLERHGLINFGIY Sbjct: 61 NSDTVLVHRVHSYLERHGLINFGIY 85 >3L1R-A nrPDB Length = 478 Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 94/337 (27%), Positives = 140/337 (41%), Gaps = 49/337 (14%) Query: 506 EKLQELEANPPSDVYLSSRDRQILDWHFAN----LEFANATPLSTLSLKHWDQDDDFEFT 561 ++L E + N P+ D D+ FA N PL+T S D DD F Sbjct: 144 QRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFS----DFGDDVYFV 199 Query: 562 GSHLTVRNGYSCVPVALA-----------EGLD--IKLNTAVRQVRYTASGCEVIAVNTR 608 + GY V LA + +D ++LN VR+++Y+ G V Sbjct: 200 AD----QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTV------ 249 Query: 609 STSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDR 668 T +Y D V+ + LGVL Q +QF P LP WK A+ + + L F R Sbjct: 250 KTEDNSVYSADYVMVSASLGVL--QSDLIQFKPKLPTWKVRAIYQFDMAVYTMIFLKFPR 307 Query: 669 VFW--DPSVNLFGHVGSTTASRGELFLFWNLY-KAPILLALVAGEAAGIMENISDDVIVG 725 FW F + S G F Y A +LL V E + +E SD+ Sbjct: 308 KFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKA 367 Query: 726 RCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPS 785 + +L+ +F VP + +V RW +D + +G++S G + +YD + P+ Sbjct: 368 EIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVG---- 423 Query: 786 IPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 R++F GEHT +Y VHGA LSG+ A Sbjct: 424 ---------RVYFTGEHTSEHYNGYVHGAYLSGIDSA 451 Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 59/104 (56%), Gaps = 2/104 (1%) Query: 280 KVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 338 +VI++G+G+SG++AA++L G+ D+ +LEA D +GGR+ +LGA V G+ Sbjct: 6 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 65 Query: 339 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEF 382 G M + VN L K++ ++ Q V KE + ++++ Sbjct: 66 GGKMNPIWPIVNSTL-KLRNFRSDFDYLAQNVYKEDGGVYDEDY 108 >3BI4-A nrPDB Length = 516 Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 76/297 (25%), Positives = 116/297 (39%), Gaps = 81/297 (27%) Query: 600 CEVIAVNTRSTSQTF--------IYKCDAVLCTLPLGVL-------KQQPPAVQFVPPLP 644 CEV ++ TR S+ +Y D V+ T+P VL K ++F PPL Sbjct: 221 CEVKSI-TREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLK 279 Query: 645 EWKTSAVQRMGFGNLNKVVLCFDRVFWDP----------SVNLFGHVGSTTASRGEL--- 691 A ++ FG L KV+ F+ W S N F + + EL Sbjct: 280 PVIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSM 339 Query: 692 ------------------FLFWNLYKAP---ILLALVAGEAAGIMENISDD--------- 721 F NL K+ + L+ +E+I +D Sbjct: 340 LEREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQ 399 Query: 722 -VI--VGRCLA---ILKGI-----FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSG 770 V+ + +CL ++ G+ ++ P + +VS W DP++RG+YS A G Sbjct: 400 PVLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYS---ACFPG 456 Query: 771 NDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIAD 827 +D M ++ G R+ FAGEHTI + +GA SG REA RI+D Sbjct: 457 DDPVDMVVAMSNGQD--------SRIRFAGEHTIMDGAGCAYGAWESGRREATRISD 505 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 35/82 (42%), Positives = 49/82 (59%), Gaps = 8/82 (9%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVAT---FRKGNYVADL 329 P KK KVIIIG+G++GL AA L G+ D +LEARDRVGGR+ T ++ Y D+ Sbjct: 6 PAKK--KVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKY--DI 61 Query: 330 GAMVVTGLGGNPMAVVSKQVNM 351 GA NP+ + Q+++ Sbjct: 62 GASWHHDTLTNPLFLEEAQLSL 83 >1O5W-A nrPDB Length = 534 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 24/202 (11%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNY-VADLGAMVVTGLGG 339 V++IG G+SGLAAA+ L + ++V +LEARDRVGGR T R + D+G V G Sbjct: 24 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYV-GPTQ 82 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYE-ANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDF 398 N + +SK++ +E K+ L + G+ P F + +Y LD+ Sbjct: 83 NRILRLSKELGIETYKVNVNERLVQYVKGKTYP------FRGAFPPVWNPLAY----LDY 132 Query: 399 NVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKEL 458 N L +G+ + V Q +H ++ W K+ +K+L++K+ K +E Sbjct: 133 NNLWRTMDEMGKEIPVDAPWQARHAQE-----WDKMT-----MKDLIDKICWTKTA-REF 181 Query: 459 HQQYKEASEVKPPRDITAEFLV 480 + + P +++A + + Sbjct: 182 AYLFVNINVTSEPHEVSALWFL 203 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 52/254 (20%), Positives = 95/254 (37%), Gaps = 34/254 (13%) Query: 581 GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFV 640 G +KL++ V + T V +N Y+C V+ +P +L + + F Sbjct: 243 GDKVKLSSPVTYIDQTDDNIIVETLNHEH------YECKYVISAIP-PILTAK---IHFK 292 Query: 641 PPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKA 700 P LP + +QR+ G + K ++ + FW + G E + L Sbjct: 293 PELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKK----DYCGCMIIEDEEAPIAITLDDT 348 Query: 701 ------PILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRAD 754 P ++ + A + + D+ + + + GS P W + Sbjct: 349 KPDGSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEE 408 Query: 755 PWARGSYS-YVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHG 813 ++ G Y+ Y G +M Q G I QP+ R++FAG T + + G Sbjct: 409 QYSGGCYTAYFPPG-------IMTQY---GRVIR---QPVGRIYFAGTETATQWSGYMEG 455 Query: 814 ALLSGLREAGRIAD 827 A+ +G R A + + Sbjct: 456 AVEAGERAAREVLN 469 >2BXR-A nrPDB Length = 527 Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 35/78 (44%), Positives = 50/78 (64%), Gaps = 4/78 (5%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKG--NYVADLGAMVVTGLG 338 V++IG G+SGL+AA+ L +G+ V +LEARDRVGGR T R +YV GA V G Sbjct: 16 VVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYV--GPT 73 Query: 339 GNPMAVVSKQVNMELAKI 356 N + +SK++ +E K+ Sbjct: 74 QNRILRLSKELGIETYKV 91 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 50/254 (19%), Positives = 94/254 (37%), Gaps = 34/254 (13%) Query: 581 GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFV 640 G +KLN V V ++ + +N Y+C V+ +P + + + F Sbjct: 235 GDQVKLNHPVTHVDQSSDNIIIETLNHEH------YECKYVINAIPPTLTAK----IHFR 284 Query: 641 PPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKA 700 P LP + +QR+ G + K ++ + FW + G + + L Sbjct: 285 PELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKK----DYCGCMIIEDEDAPISITLDDT 340 Query: 701 ------PILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRAD 754 P ++ + A + + ++ + + + GS P W + Sbjct: 341 KPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEE 400 Query: 755 PWARGSYS-YVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHG 813 ++ G Y+ Y G +M Q G I QP+ R+FFAG T + + G Sbjct: 401 QYSGGCYTAYFPPG-------IMTQ---YGRVI---RQPVGRIFFAGTETATKWSGYMEG 447 Query: 814 ALLSGLREAGRIAD 827 A+ +G R A + + Sbjct: 448 AVEAGERAAREVLN 461 >1REO-A nrPDB Length = 486 Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 27/54 (50%), Positives = 39/54 (72%), Gaps = 2/54 (3%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAM 332 V+++G+G+SGL+AA L G VT+LEA +R GGRV T+R K ++ A+LG M Sbjct: 36 VVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLGPM 89 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 62/295 (21%), Positives = 118/295 (40%), Gaps = 57/295 (19%) Query: 548 SLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLD--IKLNTAVRQVRYTASGCEVI-- 603 SL+H DD F + + G +P ++ ++ + LN V +++ A V+ Sbjct: 220 SLRH---DDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVTVVYQ 276 Query: 604 --AVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNK 661 A S + ++ ++CT + ++F PPLP K A++ + + + K Sbjct: 277 TPAKEMASVTADYV-----IVCTTSRATRR-----IKFEPPLPPKKAHALRSVHYRSGTK 326 Query: 662 VVLCFDRVFW-DPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD 720 + L + FW D + H G +T F+++ + + ++ G N Sbjct: 327 IFLTCTKKFWEDEGI----HGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQ 382 Query: 721 DVIVGRCLAILKGIFGSSAVPQ-PKE--------TVVSRWRADPWARGSYSYVAAGSSGN 771 + C I+ I S + Q P+E +++ +W D +A G + + Sbjct: 383 ALDFKDCADIV--INDLSLIHQLPREEIQTFCYPSMIQKWSLDKYAMGGITTF----TPY 436 Query: 772 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHG----ALLSGLREA 822 + ++ +T + R++FAGEHT A HG + SGLR A Sbjct: 437 QFQHFSESLTAS---------VDRIYFAGEHT-----AEAHGWIDSTIKSGLRAA 477 >2BK5-A nrPDB Length = 520 Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 34/87 (39%), Positives = 53/87 (60%), Gaps = 5/87 (5%) Query: 288 VSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLGGNPMAVV 345 +SG+AAA+ L G++V +LEARDRVGGR T R K YV DLG V G N + + Sbjct: 14 ISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSYV-GPTQNRILRL 71 Query: 346 SKQVNMELAKIKQ-KCPLYEANGQAVP 371 +K++ +E K+ + + ++ G++ P Sbjct: 72 AKELGLETYKVNEVERLIHHVKGKSYP 98 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 50/239 (20%), Positives = 92/239 (38%), Gaps = 43/239 (17%) Query: 629 VLKQQPPA----VQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGST 684 V+ PP + F PPLP + + R+ G++ K ++ + FW + G+ Sbjct: 260 VISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKK----DYCGTM 315 Query: 685 TASRGELFLFWNL--------YKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFG 736 E + + L Y A ++ + A + ++ + + + + + G Sbjct: 316 IIDGEEAPVAYTLDDTKPEGNYAA--IMGFILAHKARKLARLTKEERLKKLCELYAKVLG 373 Query: 737 SSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRL 796 S +P W + ++ G Y+ Y + + QP+ R+ Sbjct: 374 SLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLR------------QPVDRI 421 Query: 797 FFAGEHTIRNYPATVHGALLSGLREAG-RIADQFLGAMYTLPR----QATP---GVPAQ 847 +FAG T ++ + GA+ EAG R A + L AM +P Q+ P VPAQ Sbjct: 422 YFAGTETATHWSGYMEGAV-----EAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQ 475 >3RHA-A nrPDB Length = 482 Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 24/39 (61%), Positives = 31/39 (79%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVAT 319 V+I+G+G SGL AAR+L+ G+ V +LEARDRVGGR T Sbjct: 10 VVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGRTWT 48 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 48/183 (26%), Positives = 78/183 (42%), Gaps = 14/183 (7%) Query: 581 GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFV 640 G D+ LN+ VR +++ +G V V+ R+T V+ +P + + V F Sbjct: 228 GDDVVLNSPVRTIKWDENGVSV--VSERATVNARF-----VIMAVPPNLYSR----VSFD 276 Query: 641 PPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKA 700 PPLP + Q G + KV +D FW L G S A E++ N + Sbjct: 277 PPLPRRQHQMHQHQSLGLVIKVHAVYDTPFWREE-GLSGTGFSAGALVQEVYDNTNHGDS 335 Query: 701 -PILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARG 759 L+ V+ E A + +S + L + G G A+ P+ S W ++ W RG Sbjct: 336 RGTLVGFVSDEKADAVFELSAEDRKKAILESIAGFLGDKALT-PEVYYESDWGSEEWTRG 394 Query: 760 SYS 762 +Y+ Sbjct: 395 AYA 397 >3KVE-A nrPDB Length = 486 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 27/56 (48%), Positives = 38/56 (67%), Gaps = 2/56 (3%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVV 334 V+++G+G+SGL+AA L G VT+LEA +R GGRV T R K + A+LG M + Sbjct: 36 VVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRNSKEGWYANLGPMRI 91 Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 67/305 (21%), Positives = 123/305 (40%), Gaps = 62/305 (20%) Query: 548 SLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLD--IKLNTAVRQVRYTASGCEVIA- 604 SLKH DD F + + G +P ++ ++ +K N V +++ A+ V Sbjct: 220 SLKH---DDIFAYEKRFDEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVTVTYQ 276 Query: 605 ---VNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNK 661 +T S + ++ ++CT + +QF PPLP K A++ + + + K Sbjct: 277 TPEKDTSSNTADYV-----IVCTTSRAARR-----IQFEPPLPPKKQHALRSVHYRSGTK 326 Query: 662 VVLCFDRVFW-DPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD 720 + L FW D + H G +T F+++ + + ++ G N Sbjct: 327 IFLTCSSKFWEDDGI----HGGKSTTDLPSRFIYYPNHNFSTGVGVIIAYGIGDDANFFQ 382 Query: 721 DVIVGRCLAILKGIFGS-SAVPQ-PKE--------TVVSRWRADPWARGSYSYVAAGSSG 770 + C I +F S + Q PKE +++ +W D +A G+ + Sbjct: 383 ALKFKDCADI---VFNDLSLIHQLPKEEIQSFCYPSMIQKWSLDKYAMGAITTFTP---- 435 Query: 771 NDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGAL-------LSGLREAG 823 + ++ +T APQ R+FFAGE+T A HG + L+ R+ Sbjct: 436 YQFQRFSEALT-------APQ--GRIFFAGEYT-----AEAHGWIDSTIKSGLTAARDVN 481 Query: 824 RIADQ 828 R ++Q Sbjct: 482 RASEQ 486 >1SEZ-A nrPDB Length = 504 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/160 (28%), Positives = 81/160 (50%), Gaps = 16/160 (10%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 +V +IG+GVSGLAAA +L+ G++VT+ EA + GG++ + + + D GA +T G Sbjct: 15 RVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTESEG 74 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEA------NGQAV--PKEKDEMVEQEFNRLLEATSY 391 + V+ ++ + KQ+ PL + NG V P ++++ F L S Sbjct: 75 D----VTFLIDSLGLREKQQFPLSQNKRYIARNGTPVLLPSNPIDLIKSNF---LSTGSK 127 Query: 392 LSHQLDFNVLNNKPVS-LGQALEVVIQLQEKHVKDEQIEH 430 L L+ + NK +S + + E V ++H E +++ Sbjct: 128 LQMLLEPILWKNKKLSQVSDSHESVSGFFQRHFGKEVVDY 167 >4IV9-A nrPDB Length = 557 Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 29/60 (48%), Positives = 42/60 (70%), Gaps = 5/60 (8%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVAT--FRKG--NYVADLGAM 332 T +V I+G+G+SGL AA +L G+ DV L E+RDR+GGRV + F + Y+A++GAM Sbjct: 38 TPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAM 97 >1F8S-A nrPDB Length = 498 Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 26/54 (48%), Positives = 38/54 (70%), Gaps = 2/54 (3%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAM 332 V+I+G+G++GL+AA L G VT+LEA +R GGRV T+R + + A+LG M Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANLGPM 89 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 61/287 (21%), Positives = 113/287 (39%), Gaps = 41/287 (14%) Query: 548 SLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNT 607 SLKH DD F + + +G +P A+ + K++ + ++ + +V V Sbjct: 220 SLKH---DDIFAYEKRFDEIVDGMDKLPTAMYRDIQDKVHFNAQVIKIQQNDQKVTVVYE 276 Query: 608 RSTSQTFIYKCDAVL-CTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCF 666 + +T D V+ CT V ++F PPL K A++ + + + K+ L Sbjct: 277 TLSKETPSVTADYVIVCTTSRAV-----RLIKFNPPLLPKKAHALRSVHYRSGTKIFLTC 331 Query: 667 DRVFW-DPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVG 725 FW D + H G +T F+++ + + ++ G N + Sbjct: 332 TTKFWEDDGI----HGGKSTTDLPSRFIYYPNHNFTNGVGVIIAYGIGDDANFFQALDFK 387 Query: 726 RCLAILKGIFGS-SAVPQ-PKE--------TVVSRWRADPWARGSYSYVAAGSSGNDYDL 775 C I +F S + Q PK+ +V+ +W D +A G + + Sbjct: 388 DCADI---VFNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYAMGGITTFTPYQ----FQH 440 Query: 776 MAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 + P+T R++FAGE+T + + + + SGLR A Sbjct: 441 FSDPLTASQG---------RIYFAGEYTAQAH-GWIDSTIKSGLRAA 477 >2JB2-A nrPDB Length = 489 Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 26/54 (48%), Positives = 35/54 (64%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329 K + V+++G G +GL +A +LQ G VT+LEAR R GGRV T R G+ DL Sbjct: 9 KGSHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGRVWTARGGSEETDL 62 Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust. Identities = 41/206 (19%), Positives = 80/206 (38%), Gaps = 23/206 (11%) Query: 618 CDAVLCTLP---LGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPS 674 D +CT+P +G L+ P + L K S+ ++G + + R +W+ Sbjct: 285 ADYAICTIPPHLVGRLQNNLPG-DVLTALKAAKPSSSGKLG--------IEYSRRWWETE 335 Query: 675 VNLFGHVGSTTASRGELFLFWNLY---KAPILLALVAGEAAGIMENISDDVIVGRCLAIL 731 ++G +T ++ ++ Y + ++ +G+ E+++ + + +A Sbjct: 336 DRIYGGASNTDKDISQIMFPYDHYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEG 395 Query: 732 KGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQ 791 I G + WR R YS A + TP + Sbjct: 396 SEIHGEKYTRDISSSFSGSWR-----RTKYSESAWANWAGSGGSHGGAATP--EYEKLLE 448 Query: 792 PIPRLFFAGEHTIRNYPATVHGALLS 817 P+ +++FAG+H + N A HGAL S Sbjct: 449 PVDKIYFAGDH-LSNAIAWQHGALTS 473 >2VVL-G nrPDB Length = 495 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 27/62 (43%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Query: 275 TKKTG--KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAM 332 T K G VI+IG G GL A R L G LLEARDR+GGR + Y ++G Sbjct: 34 TDKDGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSNIDGYPYEMGGT 93 Query: 333 VV 334 V Sbjct: 94 WV 95 >6CR0-A nrPDB Length = 440 Score = 47.0 bits (110), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 21/42 (50%), Positives = 30/42 (71%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGR 316 T+K I++G+G SGL AAR+L + G V ++EAR R+GGR Sbjct: 5 TEKIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGR 46 Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust. Identities = 79/300 (26%), Positives = 111/300 (37%), Gaps = 67/300 (22%) Query: 548 SLKHWDQDDDFEFTGS--HLTVRNGYSCVPVALAEGL--DIKLNTAVRQVRYTASGCEVI 603 +L WD FT S V+ G + + A+ + D + V V T +G V Sbjct: 191 ALASWDT---ITFTDSEKRYHVQGGTNALCQAIFDDCRADSEFGVPVEAVAQTDNGVTVT 247 Query: 604 AVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQR--MGFG---- 657 + R +++ + TLP V V+F PPLP K + ++ M G Sbjct: 248 LADKR------VFRALTCVLTLPTKVYAD----VRFEPPLPPEKRAFIEHAEMADGAELY 297 Query: 658 -----NLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAA 712 NL D DP N F V T A EL IL + ++ Sbjct: 298 VHVRQNLGNTFTFCD----DP--NPFNAV-QTYAYDDEL--------GTILKITIGRQSL 342 Query: 713 GIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGND 772 +EN D I A ++ I G V E + W D +AR SY + G Sbjct: 343 INLENF--DAIA----AEIRKIHGDVEV---LEALPYNWAMDEYARTSYPAMRKGWFSR- 392 Query: 773 YDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGA 832 Y MA+P RLFFAG T + + GA+ SG+R GR F+ A Sbjct: 393 YKDMAKPEN-------------RLFFAGSATADGWHEYIDGAIESGIR-VGREIRHFMKA 438 >4DGK-A nrPDB Length = 501 Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 23/53 (43%), Positives = 32/53 (60%) Query: 283 IIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVT 335 +IG+G GLA A +LQ+ G+ V LLE RD+ GGR + + D G V+T Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVIT 58 >3LOV-A nrPDB Length = 475 Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 22/53 (41%), Positives = 40/53 (75%), Gaps = 2/53 (3%) Query: 280 KVIIIGSGVSGLAAARQLQ-SF-GMDVTLLEARDRVGGRVATFRKGNYVADLG 330 +++I+G G++GLAAA + +F +++TLLEA +R+GG+VAT+R+ + + G Sbjct: 6 RLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERG 58 >2IVE-A nrPDB Length = 478 Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 23/58 (39%), Positives = 32/58 (55%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG 330 +P V ++G G+SGLA A L+S G D LLE+ R+GG V T Y+ + G Sbjct: 11 MPRTTGMNVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGTHALAGYLVEQG 68 >3I6D-A nrPDB Length = 470 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/56 (39%), Positives = 37/56 (66%), Gaps = 6/56 (10%) Query: 281 VIIIGSGVSGLAAARQLQ------SFGMDVTLLEARDRVGGRVATFRKGNYVADLG 330 V+IIG G++GLAAA ++ + +++TL+EA RVGG++ T +K Y+ + G Sbjct: 8 VVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKKDGYIIERG 63 >5MOG-A nrPDB Length = 497 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 21/48 (43%), Positives = 33/48 (68%), Gaps = 1/48 (2%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR 321 PTK +V+I G+G++GL+ A+ L G LLEARD +GG++A ++ Sbjct: 14 PTKPL-QVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWK 60 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 25/46 (54%) Query: 784 PSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQF 829 P P PI + AG++T + Y A++ GA+LSG A + + + Sbjct: 427 PCRPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQSVVEDY 472 >4ZCC-A nrPDB Length = 336 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGN 340 + IIG+G++GL+AA+ L S G V L + GGR+++ R D+GA T Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAGSLDMGAQYFTAR-DR 63 Query: 341 PMAVVSKQVNMELAKIKQKCP-LYEANGQAVPKEKDEMVE 379 A KQ + + + P LY +G + DE V Sbjct: 64 RFATAVKQWQAQ-GHVSEWTPLLYNFHGGRLSPSPDEQVR 102 >3KYB-A nrPDB Length = 390 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 25/39 (64%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 K+ K++I+G+G SG RQL G V +++ RD +GG Sbjct: 2 KSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGG 40 >3NK2-X nrPDB Length = 431 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 19/35 (54%), Positives = 24/35 (68%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGR 316 I++G G SGL AAR L + G V LLE +R+GGR Sbjct: 5 IVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGR 39 >3KKJ-A nrPDB Length = 336 Score = 39.7 bits (91), Expect = 0.006, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 32/55 (58%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVT 335 + IIG+G++GL+AA+ L + G V L + GGR+++ R D+GA T Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGALDMGAQYFT 59 >3K30-A nrPDB Length = 690 Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust. Identities = 20/38 (52%), Positives = 26/38 (68%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV 317 +V+++G+G SGL AAR L G DV L EA +GGRV Sbjct: 393 RVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRV 430 >3LXD-A nrPDB Length = 415 Score = 38.9 bits (89), Expect = 0.010, Method: Compositional matrix adjust. Identities = 21/37 (56%), Positives = 25/37 (67%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVA 318 ++IG G GL AA L FG++VTLLEA RV RVA Sbjct: 156 VVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVA 192 >5GJK-A nrPDB Length = 94 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Query: 192 EAACFPDIISGPQQ--TQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLV 249 E P+ +G + T +++L RN + + NP+ LT A + L D V Sbjct: 21 ERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNL----TGDVCAV 76 Query: 250 HRVHSYLERHGLINFGI 266 RVH++LE+ GL+N+ + Sbjct: 77 MRVHAFLEQWGLVNYQV 93 >4YRY-B nrPDB Length = 468 Score = 38.5 bits (88), Expect = 0.013, Method: Compositional matrix adjust. Identities = 20/46 (43%), Positives = 26/46 (56%) Query: 270 IKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 +KPL K KV ++GSG +GL AA L G V + EA + GG Sbjct: 132 VKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGG 177 >5NMX-A nrPDB Length = 425 Score = 37.7 bits (86), Expect = 0.022, Method: Compositional matrix adjust. Identities = 34/136 (25%), Positives = 62/136 (45%), Gaps = 10/136 (7%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 +V ++G+G SGL AAR L+ G +V + E VGG + ++++ G V + + Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGG-TWNYTDETWMSEDGRPVYSSMYQ 61 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSH-QLDF 398 N + K++ M P ++ G VP ++ V + F+ +A +L Sbjct: 62 NLFVNLPKEL-MAFPDF----PFHDIEGSYVPSKE---VLKYFDNFTDAFDLRKLIKLQH 113 Query: 399 NVLNNKPVSLGQALEV 414 +V N +P G + V Sbjct: 114 HVENVRPCESGWLVTV 129 >5VJ7-A nrPDB Length = 476 Score = 37.0 bits (84), Expect = 0.034, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Query: 252 VHSYLERHGLINFGIYKRIKPLPTKKTGK-VIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 V Y HG+ + + + IK + K+ GK V IIG+G +GL A L G +VT+ EA Sbjct: 129 VADYAREHGIDDELLLEEIKGI--KRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL 186 Query: 311 DRVGG 315 + GG Sbjct: 187 HQPGG 191 >5JFC-L nrPDB Length = 474 Score = 36.6 bits (83), Expect = 0.043, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Query: 252 VHSYLERHGLINFGIYKRIKPLPTKKTGK-VIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 V Y HG+ + + + IK + K+ GK V IIG+G +GL A L G +VT+ EA Sbjct: 129 VADYAREHGIDDELLLEEIKGI--KRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL 186 Query: 311 DRVGG 315 + GG Sbjct: 187 HQPGG 191 >5TUK-A nrPDB Length = 408 Score = 35.8 bits (81), Expect = 0.091, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 19/101 (18%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 K+++IG+G++G A L+ FG L+E R A RKG + D+ + + Sbjct: 27 KILVIGAGIAGPAVCYWLRRFGFSPILVE-------RCANLRKGGHAVDIRGVAID--LA 77 Query: 340 NPMAVVSKQVNM----ELAKIKQKCPLYEANGQAVPKEKDE 376 M + K NM EL + +A G + +EK E Sbjct: 78 KSMGIYKKICNMRTQVELGR------YVDAEGNILHEEKGE 112 >3X0V-A nrPDB Length = 541 Score = 35.4 bits (80), Expect = 0.12, Method: Compositional matrix adjust. Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 8/60 (13%) Query: 280 KVIIIGSGVSGLAAARQLQSF---GMDVTLLEARDRVGGRVATFR----KGNYVADLGAM 332 KV I+G+GVSGL A L + + E+ R GGR+ T K +Y D+GAM Sbjct: 9 KVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFTDAKHDYY-DIGAM 67 >3RFW-A nrPDB Length = 252 Score = 35.0 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 6/114 (5%) Query: 356 IKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVV 415 I Q L +A Q + EKD + +E +R +A L + +LN + + Sbjct: 45 IMQDLILQDAKKQNL--EKDPLYTKELDRAKDAI--LVNVYQEKILNTIKIDAAKVKAFY 100 Query: 416 IQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVK 469 Q ++K+VK +++ +V T++E K+++N++ LK KEL ++ E ++ K Sbjct: 101 DQNKDKYVKPARVQAKHILVATEKEAKDIINELKGLKG--KELDAKFSELAKEK 152 >1I8T-A nrPDB Length = 367 Score = 35.0 bits (79), Expect = 0.15, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 22/38 (57%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVAT 319 II+GSG+ G A +L+ V ++E R+ +GG T Sbjct: 5 IIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYT 42 >2TMD-A nrPDB Length = 729 Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 25/43 (58%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV 317 TK V+I+G+G SG AAR L G V L + +++GG + Sbjct: 386 TKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHL 428 >3WE0-A nrPDB Length = 580 Score = 34.3 bits (77), Expect = 0.23, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Query: 273 LPTKKTGK-VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV---ATFRKGNYVAD 328 +P + G+ V I+G+G++GL AA +L G+ + EA ++GGR+ A +A+ Sbjct: 59 IPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEA-SKMGGRLRSQAFNGTDGIIAE 117 Query: 329 LGAM 332 LG M Sbjct: 118 LGGM 121 >4IVM-B nrPDB Length = 483 Score = 33.9 bits (76), Expect = 0.32, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 7/61 (11%) Query: 281 VIIIGSGVSGLAAARQLQSFGM--DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 338 V+++G G+SGLAA+ L V L+E+ +R+GG + + R N GA+ G G Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPN-----GAIFELGPG 65 Query: 339 G 339 G Sbjct: 66 G 66 >4EMJ-A nrPDB Length = 410 Score = 33.9 bits (76), Expect = 0.34, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 260 GLINFGIYKRIKPLPTKKTG--KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV 317 G++ Y ++ L T +++I+G G+ G A + G+ VT+LEA D + RV Sbjct: 123 GVVTLRTYGDVQVLRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRV 182 Query: 318 ATFRKGNY----VADLGAMVVTGLG 338 R G + + +LG V G G Sbjct: 183 LGRRIGAWLRGLLTELGVQVELGTG 207 >5TUF-A nrPDB Length = 409 Score = 33.5 bits (75), Expect = 0.36, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 14/113 (12%) Query: 265 GIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGN 324 G+ R + TK K+++IG GV+G A A L+ FG L+E + A RKG Sbjct: 13 GLVPRGSHMMTKHI-KILVIGVGVAGPAVAYWLKRFGFSPVLIE-------KSAAVRKGG 64 Query: 325 YVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLY-EANGQAVPKEKDE 376 D+ + T + M + + NM + + KC Y + G + +E+ E Sbjct: 65 QALDIRG-IATHI-AKEMGIYDQICNM---RTQIKCGRYVDVKGNVLHEEQGE 112 >2YVV-A nrPDB Length = 338 Score = 33.1 bits (74), Expect = 0.59, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 10/75 (13%) Query: 396 LDFNVLNNKPV--SLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKE 453 LD+N+L NKP L +E +LQ+K K+ V T+ E K+ L+K +NLK Sbjct: 58 LDYNLLTNKPNIDGLATKVETAQKLQQKADKE--------TVYTKAESKQELDKKLNLKG 109 Query: 454 KIKELHQQYKEASEV 468 + ++K A+ V Sbjct: 110 GVMTGQLKFKPAATV 124 >4HAM-A nrPDB Length = 134 Score = 32.7 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 60/116 (51%), Gaps = 6/116 (5%) Query: 357 KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSH-QLDFNVLNNKPVSLGQALEVV 415 K + P+YE Q + ++ + V QE ++L + S ++ N ++ L + EV+ Sbjct: 10 KSQLPIYEQIVQKIKEQVVKGVLQEGEKILSIREFASRIGVNPNTVSKAYQEL-ERQEVI 68 Query: 416 IQLQEKHV----KDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASE 467 I ++ K + +++ KK+ +T+ +LKE + +V L I+E+H+ E S+ Sbjct: 69 ITVKGKGTFIANQTDKLSSPKKLAETRTKLKETILDLVYLGVNIEEIHKLADEYSQ 124 >4AP1-A nrPDB Length = 549 Score = 32.7 bits (73), Expect = 0.62, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 4/52 (7%) Query: 268 KRIKPLPTKKTG----KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 + + P TG V+++G+G++GL A + +S G+ V EA VGG Sbjct: 7 RSVVTAPDATTGTTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGG 58 >2DCE-A nrPDB Length = 111 Score = 32.7 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 14/107 (13%) Query: 161 EEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQ-QTQKVFLFIRNRTLQ 219 EEE PE+ ++ Q +E P+ G Q +T + +L IRN L Sbjct: 9 EEEELKPPEQEIEIDRNIIQE---------EEKQAIPEFFEGRQAKTPERYLKIRNYILD 59 Query: 220 LW-LDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFG 265 W + PK T + D + R+H+YLE G INFG Sbjct: 60 QWEICKPKY---LNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFG 103 >4OVI-A nrPDB Length = 542 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 22/35 (62%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 V+++G+G SGL A +L+ G V ++E VGG Sbjct: 19 VLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG 53 >3RP7-A nrPDB Length = 407 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 21/30 (70%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEA 309 K I+IG+G+ GL+AA L+ G+D + EA Sbjct: 25 KAIVIGAGIGGLSAAVALKQSGIDCDVYEA 54 >4UIR-A nrPDB Length = 646 Score = 31.6 bits (70), Expect = 1.5, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 265 GIYKRIKPLPTKK--TGKVIIIGSGVSGLAAARQLQSFGM----DVTLLEARDRVGGRV 317 G Y+R K +P + K+ IIGSG++G++AA G ++T LE GG + Sbjct: 47 GNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSL 105 >3FXA-A nrPDB Length = 201 Score = 31.6 bits (70), Expect = 1.5, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 9/66 (13%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMD---VTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 TGK+++ G G SG+AA + + SF L D V G + +K + +++ Sbjct: 45 TGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDI------LIL 98 Query: 335 TGLGGN 340 GGN Sbjct: 99 ISKGGN 104 >2FQ3-A nrPDB Length = 104 Score = 31.6 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 39/83 (46%), Gaps = 6/83 (7%) Query: 186 DRMTSQEAACFPDIISG--PQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYN 243 +++ S E P+ + P +T +V++ RN + + NP + + + + Sbjct: 23 EKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNV----S 78 Query: 244 SDTVLVHRVHSYLERHGLINFGI 266 D + R+H +L + GLIN+ + Sbjct: 79 GDAAALFRLHKFLTKWGLINYQV 101 >2R9Z-A nrPDB Length = 463 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 23/34 (67%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 +V IIG+G G+ A L+SFG +VT++ DR+ Sbjct: 168 RVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRL 201 >2E5V-A nrPDB Length = 472 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 2/51 (3%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGA 331 + IIGSG++GL+A L+ G VTL+ R+ G KG A +G+ Sbjct: 2 IYIIGSGIAGLSAGVALRRAGKKVTLISK--RIDGGSTPIAKGGVAASVGS 50 >3CF4-A nrPDB Length = 807 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 51/92 (55%), Gaps = 10/92 (10%) Query: 407 SLGQALEVV--IQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKE 464 S+G+A+++ ++L +K++ ++ E W K V+T+ +L + + +KEL +++ Sbjct: 720 SMGRAIKLTHWMELHKKYLGGKEPEDWWKFVRTEADL-----PLATREALLKELEKEHGW 774 Query: 465 ASEVKPPRDITA---EFLVKSKHRDLTALCKE 493 + K + I+ +F V ++ +L LCKE Sbjct: 775 EIDWKRKKIISGPKIKFDVSAQPTNLKRLCKE 806 >5J5Z-A nrPDB Length = 496 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 K+++IG+GV G+ Q G DVT +E VGG Sbjct: 202 KMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGG 237 >5TUM-A nrPDB Length = 410 Score = 31.2 bits (69), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 7/53 (13%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329 K K+++IG+GV+G A L+ FG L+E + A+ RKG D+ Sbjct: 24 KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIE-------KYASIRKGGQALDV 69 >4TNS-A nrPDB Length = 151 Score = 31.2 bits (69), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query: 421 KHVKDEQIEHWKK--IVKTQEELKELLN----KMVNLKEKIKELHQQYKEASEVKPPRDI 474 KH + + W++ I +TQEE EL+N K+ + +E + L Q+ + S K D+ Sbjct: 51 KHSQSRRPSSWRQEQITRTQEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDL 110 Query: 475 TA 476 A Sbjct: 111 GA 112 >5YGQ-A nrPDB Length = 342 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL-GAMVVTGLG 338 V+I+G+G GL A +L + L++ D+VGG+ A + D+ G +VTG G Sbjct: 9 VLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIYDIPGIPMVTGHG 67 >6IUM-B nrPDB Length = 701 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 26/52 (50%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNY 325 PT+K KV +IG+G G + + G+ VT+LE + R + NY Sbjct: 288 PTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGIIRKNY 339 >5Z70-A nrPDB Length = 605 Score = 30.8 bits (68), Expect = 2.8, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 4/42 (9%) Query: 280 KVIIIGSGVSGLAAA----RQLQSFGMDVTLLEARDRVGGRV 317 K IIGSG++GLA+A R + G D+T+L+A GG + Sbjct: 6 KAWIIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSL 47 >3GMC-A nrPDB Length = 415 Score = 30.8 bits (68), Expect = 2.9, Method: Compositional matrix adjust. Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTG 336 KT + + G G +GL AA L+ G DV L E + F G Y+ G V+ G Sbjct: 46 KTRRAEVAGGGFAGLTAAIALKQNGWDVRLHEK----SSELRAFGAGIYLWHNGLRVLEG 101 Query: 337 LG 338 LG Sbjct: 102 LG 103 >4U85-A nrPDB Length = 181 Score = 30.8 bits (68), Expect = 3.0, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query: 421 KHVKDEQIEHWK--KIVKTQEELKELLN----KMVNLKEKIKELHQQYKEASEVKPPRDI 474 KH + + W+ KI +T+EE EL+N K+ + +E + L Q+ + S K D+ Sbjct: 81 KHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDL 140 Query: 475 TA 476 A Sbjct: 141 GA 142 >3UP5-A nrPDB Length = 545 Score = 30.4 bits (67), Expect = 3.0, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 ++IG+GV+G+ A + GM V +EA + VGG Sbjct: 13 VVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGG 46 >2D0I-A nrPDB Length = 333 Score = 30.4 bits (67), Expect = 3.0, Method: Compositional matrix adjust. Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 4/48 (8%) Query: 257 ERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDV 304 E H I G +KRI+ L KK G I+G G G A AR+L FG+ + Sbjct: 129 ESHAKIWTG-FKRIESLYGKKVG---ILGMGAIGKAIARRLIPFGVKL 172 >1PS9-A nrPDB Length = 671 Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGR 316 LP + + ++G+G +GLA A + G VTL +A +GG+ Sbjct: 368 LPAVQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQ 411 >4FNP-A nrPDB Length = 729 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 4/99 (4%) Query: 481 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN 540 K + A K+ L + G L E N + +++S+ + L +F L AN Sbjct: 615 KQMMKQQVAFYKDVRRLVQF-GTFYRLLSPFEGNEAAWMFVSADRSEALVAYFRVLAEAN 673 Query: 541 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALA 579 A PLS L LK D + D+E G L V G V +A Sbjct: 674 A-PLSYLRLKGLDSNQDYEIEG--LGVYGGDELVYAGVA 709 >5T0C-AD nrPDB Length = 418 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 2/82 (2%) Query: 364 EANGQAVPKEKDEMVEQEFNRLLEATSYLSHQ-LDFNVLNNKPVSLGQALEVVIQLQEKH 422 E G V K +DE+ +R S+L + D L ++ L Q LE +++QE++ Sbjct: 2 EEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEF-LEVQEEY 60 Query: 423 VKDEQIEHWKKIVKTQEELKEL 444 +KDEQ K+ + QEE+K + Sbjct: 61 IKDEQKNLKKEFLHAQEEVKRI 82 >3JYJ-A nrPDB Length = 123 Score = 30.0 bits (66), Expect = 4.0, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query: 421 KHVKDEQIEHWKK--IVKTQEELKELLN----KMVNLKEKIKELHQQYKEASEVKPPRDI 474 KH + + W++ I +TQEE EL+N K+ + +E + L Q+ + S K D+ Sbjct: 23 KHSQSRRPSSWRQEQITRTQEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDL 82 Query: 475 TA 476 A Sbjct: 83 GA 84 >3MJ4-A nrPDB Length = 397 Score = 30.0 bits (66), Expect = 4.0, Method: Compositional matrix adjust. Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 11/95 (11%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNP 341 +I+G+G +G A +L S G V +++ R +GG D +++ G + Sbjct: 33 LIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYD------CYDDAGVLIHPYGPHI 86 Query: 342 MAVVSKQVNMELAKIKQKCP-----LYEANGQAVP 371 SK V L++ + P L +GQ +P Sbjct: 87 FHTNSKDVFEYLSRFTEWRPYQHRVLASVDGQLLP 121 >4REP-A nrPDB Length = 495 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 20/40 (50%) Query: 296 QLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVT 335 +L+ G VT+ E D GG++ K Y DLG + T Sbjct: 19 RLRHQGYSVTIFEKNDYAGGKLHAIEKDGYRFDLGPSLFT 58 >1V59-A nrPDB Length = 478 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 K+ V+IIG G +G AA + G + +E R ++GG Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGG 42 >4A6N-B nrPDB Length = 398 Score = 30.0 bits (66), Expect = 4.5, Method: Compositional matrix adjust. Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 6/49 (12%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARD-----RVGGRVATFRKG 323 V IIG G GL A+ LQ G+DV++ E RD R+ G KG Sbjct: 28 NVAIIGGGPVGLTMAKLLQQNGIDVSVYE-RDNDREARIFGGTLDLHKG 75 >5ZBC-A nrPDB Length = 451 Score = 30.0 bits (66), Expect = 5.0, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 5/61 (8%) Query: 276 KKTGKVIIIGSGVSGLAAARQL----QSFGMDVTLLEARDRVGGRV-ATFRKGNYVADLG 330 K + + I+G+G+SGL A L G+ + + + + GGR+ + G +LG Sbjct: 22 KHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKMLDGKASIELG 81 Query: 331 A 331 A Sbjct: 82 A 82 >5ER0-A nrPDB Length = 518 Score = 29.6 bits (65), Expect = 5.1, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 22/38 (57%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 K+ ++ +IG+G G A + G DVTL++A RV Sbjct: 195 KEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARV 232 >3LAD-A nrPDB Length = 476 Score = 29.6 bits (65), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 21/34 (61%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 312 GK+ +IG+GV GL G +VT+LEA D+ Sbjct: 181 GKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDK 214 >2LCK-A nrPDB Length = 303 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 32/114 (28%), Positives = 46/114 (40%), Gaps = 16/114 (14%) Query: 193 AACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQ----LTFEATLQQLEAP---YNSD 245 AAC D+I+ P T KV L I+ + L Q L T+ + E P YN Sbjct: 11 AACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGL 70 Query: 246 TVLVHRVHSYLERHGLINFGIYKRIKPLPTKKT-----GKVIIIGSGVSGLAAA 294 + R S+ + G+Y +K TK + G ++ GS LA A Sbjct: 71 VAGLQRQMSFAS----VRIGLYDSVKQFYTKGSEHAGIGSRLLAGSTTGALAVA 120 >5MJK-A nrPDB Length = 327 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR------VGGRVATFRKGNYVADLGAMV 333 ++++IG G S + A L FG VT++ RD+ + R K N++ D M Sbjct: 165 EILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPME 224 Query: 334 VTGLGGNPMAVVSKQV 349 + G +VV K V Sbjct: 225 IKGDDKKIQSVVYKNV 240 >3ULK-A nrPDB Length = 491 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 12/43 (27%), Positives = 25/43 (58%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK 322 KV+I+G G GL ++ G+D++ ++ + + A++RK Sbjct: 39 KVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRK 81 >1ZCN-A nrPDB Length = 161 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query: 421 KHVKDEQIEHWK--KIVKTQEELKELLN----KMVNLKEKIKELHQQYKEASEVKPPRDI 474 KH + + W+ KI +T+EE EL+N K+ + +E + L Q+ + S K D+ Sbjct: 61 KHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDL 120 Query: 475 TA 476 A Sbjct: 121 GA 122 >2VOU-A nrPDB Length = 397 Score = 29.6 bits (65), Expect = 5.6, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 20/31 (64%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 T ++ ++G +SGL AA L+ G+DV + E Sbjct: 5 TDRIAVVGGSISGLTAALMLRDAGVDVDVYE 35 >5JCN-A nrPDB Length = 451 Score = 29.6 bits (65), Expect = 6.1, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 22/40 (55%) Query: 268 KRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLL 307 K + + KK GK +I+G G GL + L+ DVT++ Sbjct: 170 KLVAAIQAKKGGKAVIVGGGYIGLELSAALKINDFDVTMV 209 >4K22-A nrPDB Length = 365 Score = 29.6 bits (65), Expect = 6.3, Method: Compositional matrix adjust. Identities = 15/30 (50%), Positives = 19/30 (63%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 V I+G G+ GLA A LQ G+ V +LE R Sbjct: 6 VAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >3EJB-B nrPDB Length = 404 Score = 29.6 bits (65), Expect = 6.4, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Query: 339 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVP-KEKDEMVEQEFNRLLEATSYLSHQLD 397 GN MAV + EL + +++ P + + +EKD++ E+E + H+ Sbjct: 180 GNIMAVQAMAYFKELIQKRKRHPQQDMISMLLKGREKDKLTEEEAASTCILLAIAGHETT 239 Query: 398 FNVLNNKPVSLGQALEVVIQLQE 420 N+++N + L Q E +++L+E Sbjct: 240 VNLISNSVLCLLQHPEQLLKLRE 262 >5BR7-A nrPDB Length = 393 Score = 29.6 bits (65), Expect = 6.5, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 281 VIIIGSGVSGLAAA-RQLQSFGMDVTLLEARDRVGG 315 +I++GSG+ GL A R G V ++E R +GG Sbjct: 6 LIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGG 41 >5CIO-A nrPDB Length = 793 Score = 29.3 bits (64), Expect = 7.1, Method: Compositional matrix adjust. Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 3/44 (6%) Query: 472 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANP 515 R +T EFL + H +LT + EL +TQ L++ LQ L A P Sbjct: 716 RQLTDEFL-QQMHHELTHV--SVGELEQTQQALQQNLQRLSAEP 756 >5ZYN-B nrPDB Length = 471 Score = 29.3 bits (64), Expect = 7.9, Method: Compositional matrix adjust. Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 14/101 (13%) Query: 281 VIIIGSGVSGLAAARQLQS-FGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 V++IGSG++GL + +L S + + V LL+ +GG +G+ G Sbjct: 7 VVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGN-------------SIKASSGING 53 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQ 380 M+ ++ K L+ A G+ VP D++ ++ Sbjct: 54 AHTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKE 94 >6AHD-N nrPDB Length = 941 Score = 29.3 bits (64), Expect = 8.1, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 4/92 (4%) Query: 272 PLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGA 331 P P T ++ G+G + Q ++ MD+ L + D V G+ KG Y+ DL + Sbjct: 221 PYPGGMTPGLMTPGTGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKG-YLTDLNS 279 Query: 332 MVVTGLGGNPMAVVSKQVNMELAKIKQKCPLY 363 M+ T GG+ + K+ + L +++ P + Sbjct: 280 MIPTH-GGDINDI--KKARLLLKSVRETNPHH 308 >6FTJ-1 nrPDB Length = 162 Score = 29.3 bits (64), Expect = 8.3, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Query: 414 VVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRD 473 + ++L KD E K+ E++ L+NK + L E +YK++ +V Sbjct: 18 IYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRIGLYRHFDETINRYKQSRDVSTLN- 76 Query: 474 ITAEFLVKSKHRDLTALCKEYDELAETQGK-LEEKLQELE 512 + + ++++H+ LT+ +T+G L +K+ E++ Sbjct: 77 -SGKKSLETEHKALTSEIASLQSRLKTEGSDLCDKVSEMQ 115 >4Y4M-A nrPDB Length = 290 Score = 28.9 bits (63), Expect = 9.0, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 18/28 (64%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLE 308 V+I+G+G SGL AR L G V +LE Sbjct: 62 VVIVGAGPSGLTCARYLAKEGFKVVVLE 89 >2QA2-A nrPDB Length = 499 Score = 28.9 bits (63), Expect = 9.6, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 22/33 (66%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 + VI++G+G +GL A +L+ G+DV +LE Sbjct: 10 RSDASVIVVGAGPAGLMLAGELRLGGVDVMVLE 42 >1X14-A nrPDB Length = 401 Score = 28.9 bits (63), Expect = 9.7, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 KV++IG+GV+GLAA S G V + R V Sbjct: 174 KVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEV 207 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5L3D-A nrPDB 1400 0.0 3ABT-A nrPDB 1055 0.0 2BXR-A nrPDB 395 e-110 4FWE-A nrPDB 344 7e-95 3L1R-A nrPDB 316 2e-86 1F8S-A nrPDB 258 8e-69 1REO-A nrPDB 254 1e-67 3KVE-A nrPDB 254 1e-67 1O5W-A nrPDB 223 3e-58 2COM-A nrPDB 216 4e-56 2BK5-A nrPDB 203 3e-52 2L3D-A nrPDB 200 3e-51 3BI4-A nrPDB 190 3e-48 3RHA-A nrPDB 182 4e-46 5IT3-A nrPDB 170 2e-42 1SEZ-A nrPDB 149 5e-36 2JB2-A nrPDB 131 2e-30 4ZCC-A nrPDB 107 2e-23 5MOG-A nrPDB 103 3e-22 6CR0-A nrPDB 93 6e-19 2VVL-G nrPDB 90 3e-18 3I6D-A nrPDB 81 2e-15 2IVE-A nrPDB 80 3e-15 4DGK-A nrPDB 79 1e-14 4IV9-A nrPDB 77 4e-14 3LOV-A nrPDB 72 1e-12 Sequences not found previously or not previously below threshold: 3KKJ-A nrPDB 103 4e-22 3NK2-X nrPDB 74 2e-13 5NMX-A nrPDB 67 3e-11 3WE0-A nrPDB 64 4e-10 4IVM-B nrPDB 58 1e-08 3X0V-A nrPDB 58 2e-08 5JFC-L nrPDB 56 5e-08 5VJ7-A nrPDB 56 6e-08 3K30-A nrPDB 54 3e-07 4YRY-B nrPDB 53 6e-07 4MO2-B nrPDB 52 1e-06 2GV8-A nrPDB 50 4e-06 3KYB-A nrPDB 50 4e-06 5GJK-A nrPDB 49 1e-05 3LXD-A nrPDB 48 2e-05 1PS9-A nrPDB 48 3e-05 5BR7-A nrPDB 48 3e-05 3RP7-A nrPDB 47 3e-05 4AP1-A nrPDB 47 4e-05 1V59-A nrPDB 47 5e-05 5MJK-A nrPDB 47 5e-05 2Q7V-A nrPDB 46 5e-05 2CVJ-A nrPDB 46 6e-05 5ZBC-A nrPDB 46 6e-05 4REP-A nrPDB 46 1e-04 4Y4N-A nrPDB 46 1e-04 4UIR-A nrPDB 46 1e-04 4Y4M-A nrPDB 45 1e-04 3MJ4-A nrPDB 45 1e-04 4C5O-A nrPDB 45 2e-04 3ATQ-A nrPDB 45 2e-04 4OVI-A nrPDB 45 2e-04 5TWC-A nrPDB 44 2e-04 6GAR-A nrPDB 44 3e-04 3FG2-P nrPDB 44 3e-04 1I8T-A nrPDB 44 4e-04 4X4J-A nrPDB 43 4e-04 3UKH-A nrPDB 43 5e-04 2VOU-A nrPDB 43 5e-04 2TMD-A nrPDB 43 5e-04 1RP0-A nrPDB 43 6e-04 3UP5-A nrPDB 42 7e-04 5UTH-A nrPDB 42 8e-04 4EMJ-A nrPDB 42 8e-04 5TUK-A nrPDB 42 9e-04 4JDR-A nrPDB 42 0.001 3LZX-A nrPDB 42 0.001 6GAS-A nrPDB 42 0.001 3JSK-A nrPDB 42 0.001 3BHF-A nrPDB 42 0.001 4GCM-A nrPDB 42 0.001 2GAG-B nrPDB 42 0.001 2DCE-A nrPDB 42 0.001 5XHU-A nrPDB 42 0.001 4K22-A nrPDB 42 0.001 1ZOV-A nrPDB 42 0.001 3FPZ-A nrPDB 42 0.001 6O85-E nrPDB 41 0.002 1DOD-A nrPDB 41 0.002 5Z70-A nrPDB 41 0.002 5Y77-A nrPDB 41 0.002 5L46-A nrPDB 41 0.002 4ZN0-A nrPDB 41 0.003 4A6N-B nrPDB 41 0.003 4P9S-A nrPDB 41 0.003 1NAA-A nrPDB 41 0.003 6CMZ-A nrPDB 41 0.003 3QJ4-A nrPDB 41 0.003 5EZ7-A nrPDB 40 0.004 2NVK-X nrPDB 40 0.004 3IHG-A nrPDB 40 0.004 1F6M-A nrPDB 40 0.004 5YGQ-A nrPDB 40 0.004 6BRD-A nrPDB 40 0.005 6J0Z-C nrPDB 40 0.005 4RPJ-A nrPDB 40 0.005 5TUM-A nrPDB 40 0.005 1NHQ-A nrPDB 40 0.005 3R9U-A nrPDB 39 0.006 2E5V-A nrPDB 39 0.006 5W4C-A nrPDB 39 0.007 6DLL-A nrPDB 39 0.007 4C3X-A nrPDB 39 0.007 5TUL-A nrPDB 39 0.008 2QA2-A nrPDB 39 0.008 2FQ3-A nrPDB 39 0.008 5ZYN-B nrPDB 39 0.009 3AB1-A nrPDB 39 0.009 2EQ6-A nrPDB 39 0.010 2ZBW-A nrPDB 39 0.010 2RGJ-A nrPDB 39 0.011 4B1B-A nrPDB 39 0.011 2GMH-A nrPDB 39 0.011 2YQU-A nrPDB 39 0.012 2A87-A nrPDB 39 0.012 3GMC-A nrPDB 39 0.012 4YNU-A nrPDB 38 0.013 2R9Z-A nrPDB 38 0.014 1LVL-A nrPDB 38 0.014 3URH-A nrPDB 38 0.017 4USR-A nrPDB 38 0.019 4K2X-A nrPDB 38 0.020 5UWY-A nrPDB 38 0.022 1DEQ-A nrPDB 38 0.022 2BRY-A nrPDB 37 0.023 4TXK-A nrPDB 37 0.023 4RG3-A nrPDB 37 0.024 4N9X-A nrPDB 37 0.024 6JDK-A nrPDB 37 0.025 2YVG-A nrPDB 37 0.026 5KOX-A nrPDB 37 0.027 3T14-A nrPDB 37 0.031 5J5Z-A nrPDB 37 0.032 6ER9-A nrPDB 37 0.048 4B3J-A nrPDB 36 0.050 6N7F-A nrPDB 36 0.051 6NWP-A nrPDB 36 0.052 5ZL9-A nrPDB 36 0.052 4YKF-A nrPDB 36 0.055 1FL2-A nrPDB 36 0.055 4H7U-A nrPDB 36 0.055 3ISH-A nrPDB 36 0.055 1QO8-A nrPDB 36 0.057 3LAD-A nrPDB 36 0.058 4MOP-A nrPDB 36 0.061 3II4-A nrPDB 36 0.066 6BWT-A nrPDB 36 0.067 1Q1R-A nrPDB 36 0.067 5U63-A nrPDB 36 0.070 6IUM-B nrPDB 36 0.077 1C0L-A nrPDB 36 0.077 5ER0-A nrPDB 36 0.080 6C6P-A nrPDB 36 0.082 6BZ0-A nrPDB 36 0.087 2UZZ-A nrPDB 36 0.090 5Z7M-A nrPDB 36 0.096 2WTB-A nrPDB 36 0.10 6A37-A nrPDB 36 0.10 3COX-A nrPDB 36 0.11 5USX-A nrPDB 36 0.11 2VHY-A nrPDB 36 0.11 6BPY-A nrPDB 36 0.11 5XGV-A nrPDB 35 0.12 5U8W-A nrPDB 35 0.12 3NIX-A nrPDB 35 0.13 5TR3-A nrPDB 35 0.13 3G5Q-A nrPDB 35 0.14 3RQ4-A nrPDB 35 0.15 1GPE-A nrPDB 35 0.18 5J7X-A nrPDB 34 0.19 3L8K-A nrPDB 34 0.20 4JNQ-A nrPDB 34 0.20 3SM8-A nrPDB 34 0.20 6AON-A nrPDB 34 0.20 4AU7-A nrPDB 34 0.21 4Z25-A nrPDB 34 0.23 1FOH-A nrPDB 34 0.27 1EBD-A nrPDB 34 0.28 1UKV-G nrPDB 34 0.29 1GAL-A nrPDB 34 0.30 5JCN-A nrPDB 34 0.33 2CUL-A nrPDB 34 0.33 5EVY-X nrPDB 34 0.36 5MQ0-T nrPDB 34 0.36 4NTC-A nrPDB 34 0.39 4CPD-A nrPDB 34 0.39 1KOB-A nrPDB 33 0.43 5X6R-A nrPDB 33 0.45 5Z6Q-A nrPDB 33 0.46 3IP1-A nrPDB 33 0.48 4Z44-A nrPDB 33 0.52 3NTA-A nrPDB 33 0.53 2EEZ-A nrPDB 33 0.71 5X68-A nrPDB 32 0.72 3D8X-A nrPDB 32 0.73 1OQY-A nrPDB 30 5.9 2QA1-A nrPDB 30 6.0 3OZ2-A nrPDB 29 6.3 1DXL-A nrPDB 29 9.6 >5L3D-A nrPDB Length = 852 Score = 1400 bits (3624), Expect = 0.0, Method: Composition-based stats. Identities = 851/852 (99%), Positives = 852/852 (100%) Query: 1 MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTP 60 MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTP Sbjct: 1 MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTP 60 Query: 61 RKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEY 120 RKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEY Sbjct: 61 RKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEY 120 Query: 121 REMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQ 180 REMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQ Sbjct: 121 REMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQ 180 Query: 181 SRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEA 240 SRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEA Sbjct: 181 SRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEA 240 Query: 241 PYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSF 300 PYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSF Sbjct: 241 PYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSF 300 Query: 301 GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKC 360 GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKC Sbjct: 301 GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKC 360 Query: 361 PLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQE 420 PLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQE Sbjct: 361 PLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQE 420 Query: 421 KHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLV 480 KHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLV Sbjct: 421 KHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLV 480 Query: 481 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN 540 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN Sbjct: 481 KSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFAN 540 Query: 541 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGC 600 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGC Sbjct: 541 ATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGC 600 Query: 601 EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLN 660 EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLN Sbjct: 601 EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLN 660 Query: 661 KVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD 720 KVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD Sbjct: 661 KVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISD 720 Query: 721 DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPI 780 DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGS+SYVAAGSSGNDYDLMAQPI Sbjct: 721 DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSHSYVAAGSSGNDYDLMAQPI 780 Query: 781 TPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQA 840 TPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQA Sbjct: 781 TPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQA 840 Query: 841 TPGVPAQQSPSM 852 TPGVPAQQSPSM Sbjct: 841 TPGVPAQQSPSM 852 >3ABT-A nrPDB Length = 662 Score = 1055 bits (2728), Expect = 0.0, Method: Composition-based stats. Identities = 662/662 (100%), Positives = 662/662 (100%) Query: 172 SGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTF 231 SGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTF Sbjct: 1 SGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTF 60 Query: 232 EATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGL 291 EATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGL Sbjct: 61 EATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGL 120 Query: 292 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM 351 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM Sbjct: 121 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM 180 Query: 352 ELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQA 411 ELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQA Sbjct: 181 ELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQA 240 Query: 412 LEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPP 471 LEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPP Sbjct: 241 LEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPP 300 Query: 472 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDW 531 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDW Sbjct: 301 RDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDW 360 Query: 532 HFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR 591 HFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR Sbjct: 361 HFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR 420 Query: 592 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV 651 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV Sbjct: 421 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAV 480 Query: 652 QRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEA 711 QRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEA Sbjct: 481 QRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEA 540 Query: 712 AGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN 771 AGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN Sbjct: 541 AGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN 600 Query: 772 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG 831 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG Sbjct: 601 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG 660 Query: 832 AM 833 AM Sbjct: 661 AM 662 >2BXR-A nrPDB Length = 527 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 111/559 (19%), Positives = 201/559 (35%), Gaps = 123/559 (22%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNY-VADLGAMVVTGLG 338 V++IG G+SGL+AA+ L +G+ V +LEARDRVGGR T R + D+G V G Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYV-GPT 73 Query: 339 GNPMAVVSKQVNMELAKIKQKCPLYEA-NGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 N + +SK++ +E K+ L + G+ P F + +Y LD Sbjct: 74 QNRILRLSKELGIETYKVNVSERLVQYVKGKTYP------FRGAFPPVWNPIAY----LD 123 Query: 398 FNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKE 457 +N L ++G+ + + +H + W K+ +KEL++K+ K + Sbjct: 124 YNNLWRTIDNMGKEIPTDAPWEAQHA-----DKWDKMT-----MKELIDKICWTKTA-RR 172 Query: 458 LHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPS 517 + + V S+ +++AL Sbjct: 173 FAYLFVNIN-------------VTSEPHEVSALW-------------------------- 193 Query: 518 DVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVA 577 W+ S+ + Q+ F G V Sbjct: 194 -----------FLWYVK----QCGGTTRIFSVTNGGQERKF---------VGGSGQVSER 229 Query: 578 LAE--GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPP 635 + + G +KLN V V ++ + +N Y+C V+ +P + + Sbjct: 230 IMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEH------YECKYVINAIPPTLTAK--- 280 Query: 636 AVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFW 695 + F P LP + +QR+ G + K ++ + FW + G + + Sbjct: 281 -IHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKK----DYCGCMIIEDEDAPISI 335 Query: 696 NLYKA------PILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVS 749 L P ++ + A + + ++ + + + GS P Sbjct: 336 TLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEK 395 Query: 750 RWRADPWARGSYS-YVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYP 808 W + ++ G Y+ Y G +M Q G I QP+ R+FFAG T + Sbjct: 396 NWCEEQYSGGCYTAYFPPG-------IMTQ---YGRVI---RQPVGRIFFAGTETATKWS 442 Query: 809 ATVHGALLSGLREAGRIAD 827 + GA+ +G R A + + Sbjct: 443 GYMEGAVEAGERAAREVLN 461 >4FWE-A nrPDB Length = 796 Score = 344 bits (883), Expect = 7e-95, Method: Composition-based stats. Identities = 122/332 (36%), Positives = 182/332 (54%), Gaps = 29/332 (8%) Query: 504 LEEKLQELEAN--PPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDF-EF 560 L EK++E+ S + S + Q+L +H +NLE+A + L +S + WD ++ F +F Sbjct: 483 LGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQF 542 Query: 561 TGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDA 620 G H + GYS + LAEGLDI+L + V+ + Y+ G EV T T Y Sbjct: 543 AGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYS--GDEVQVTTTDGTG----YSAQK 596 Query: 621 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSV---NL 677 VL T+PL +L Q A+QF PPL E K A+ +G G + K+ L F FWD V + Sbjct: 597 VLVTVPLALL--QKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADF 654 Query: 678 FGHVGSTTASRGELFLFW---NLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGI 734 FGHV + + RG +F+ K +L++++AGEA + + D ++ +C+A L+ + Sbjct: 655 FGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLREL 714 Query: 735 FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIP 794 F VP P + V+RW DPW + +YS+V G SG YD++A+ I Sbjct: 715 FKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQ------------G 762 Query: 795 RLFFAGEHTIRNYPATVHGALLSGLREAGRIA 826 +FFAGE T R++P TV GA LSG+REA +IA Sbjct: 763 TVFFAGEATNRHFPQTVTGAYLSGVREASKIA 794 Score = 264 bits (674), Expect = 1e-70, Method: Composition-based stats. Identities = 81/254 (31%), Positives = 128/254 (50%), Gaps = 18/254 (7%) Query: 186 DRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQL--EAPYN 243 D M E FP+ P ++L +RN L LW N K LT + + + Sbjct: 261 DVMELDELYEFPEYSRDP----TMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVR 316 Query: 244 SDTVL-VHRVHSYLERHGLINFGIYK---RIKPLPTKKTGK-VIIIGSGVSGLAAARQLQ 298 V V R+ ++ R GLIN G+ LP K VIIIG+G +GLAAARQL Sbjct: 317 IRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLH 376 Query: 299 SFGMDVTLLEARDRVGGRVATFRK-GNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIK 357 +FG+ VT+LEA+DR+GGRV + GA +V G NP+A++ +Q+ + + K Sbjct: 377 NFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFG 436 Query: 358 QKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQ 417 ++C L + G+ D+ ++ FN LL+ S + D L + P LG+ +E + + Sbjct: 437 ERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS--EWRKDKTQLQDVP--LGEKIEEIYK 492 Query: 418 --LQEKHVKDEQIE 429 ++E ++ ++E Sbjct: 493 AFIKESGIQFSELE 506 >3L1R-A nrPDB Length = 478 Score = 316 bits (810), Expect = 2e-86, Method: Composition-based stats. Identities = 94/337 (27%), Positives = 140/337 (41%), Gaps = 49/337 (14%) Query: 506 EKLQELEANPPSDVYLSSRDRQILDWHFAN----LEFANATPLSTLSLKHWDQDDDFEFT 561 ++L E + N P+ D D+ FA N PL+T S D DD F Sbjct: 144 QRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFS----DFGDDVYFV 199 Query: 562 GSHLTVRNGYSCVPVALA-----------EGLD--IKLNTAVRQVRYTASGCEVIAVNTR 608 + GY V LA + +D ++LN VR+++Y+ G V Sbjct: 200 AD----QRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVK----- 250 Query: 609 STSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDR 668 T +Y D V+ + LGVL Q +QF P LP WK A+ + + L F R Sbjct: 251 -TEDNSVYSADYVMVSASLGVL--QSDLIQFKPKLPTWKVRAIYQFDMAVYTMIFLKFPR 307 Query: 669 VFW--DPSVNLFGHVGSTTASRGELFLFWNLY-KAPILLALVAGEAAGIMENISDDVIVG 725 FW F + S G F Y A +LL V E + +E SD+ Sbjct: 308 KFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKA 367 Query: 726 RCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPS 785 + +L+ +F VP + +V RW +D + +G++S G + +YD + P+ Sbjct: 368 EIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPV----- 422 Query: 786 IPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 R++F GEHT +Y VHGA LSG+ A Sbjct: 423 --------GRVYFTGEHTSEHYNGYVHGAYLSGIDSA 451 Score = 118 bits (296), Expect = 8e-27, Method: Composition-based stats. Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 2/109 (1%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMV 333 +VI++G+G+SG++AA++L G+ D+ +LEA D +GGR+ +LGA Sbjct: 1 ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANW 60 Query: 334 VTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEF 382 V G+ G M + VN L K++ ++ Q V KE + ++++ Sbjct: 61 VEGVNGGKMNPIWPIVNSTL-KLRNFRSDFDYLAQNVYKEDGGVYDEDY 108 >1F8S-A nrPDB Length = 498 Score = 258 bits (658), Expect = 8e-69, Method: Composition-based stats. Identities = 59/288 (20%), Positives = 112/288 (38%), Gaps = 37/288 (12%) Query: 548 SLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNT 607 SLKH DD F + + +G +P A+ + K++ + ++ + +V V Sbjct: 220 SLKH---DDIFAYEKRFDEIVDGMDKLPTAMYRDIQDKVHFNAQVIKIQQNDQKVTVVYE 276 Query: 608 RSTSQTFIYKCDAVL-CTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCF 666 + +T D V+ CT V ++F PPL K A++ + + + K+ L Sbjct: 277 TLSKETPSVTADYVIVCTTSRAVR-----LIKFNPPLLPKKAHALRSVHYRSGTKIFLTC 331 Query: 667 DRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGR 726 FW+ H G +T F+++ + + ++ G N + Sbjct: 332 TTKFWEDD---GIHGGKSTTDLPSRFIYYPNHNFTNGVGVIIAYGIGDDANFFQALDFKD 388 Query: 727 CLAILKGIFGSSAVPQ-PKE--------TVVSRWRADPWARGSYSYVAAGSSGNDYDLMA 777 C I+ S + Q PK+ +V+ +W D +A G + + + Sbjct: 389 CADIV--FNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYAMGGITTFTP----YQFQHFS 442 Query: 778 QPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRI 825 P+T R++FAGE+T + + + + SGLR A + Sbjct: 443 DPLTASQ---------GRIYFAGEYTAQAH-GWIDSTIKSGLRAARDV 480 >1REO-A nrPDB Length = 486 Score = 254 bits (648), Expect = 1e-67, Method: Composition-based stats. Identities = 58/294 (19%), Positives = 116/294 (39%), Gaps = 40/294 (13%) Query: 548 SLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNT 607 SL+H DD F + + G +P ++ ++ K++ + ++ + +V V Sbjct: 220 SLRH---DDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVTVVYQ 276 Query: 608 RSTSQTFIYKCDAVL-CTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCF 666 + D V+ CT + ++F PPLP K A++ + + + K+ L Sbjct: 277 TPAKEMASVTADYVIVCTTSRATRR-----IKFEPPLPPKKAHALRSVHYRSGTKIFLTC 331 Query: 667 DRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGR 726 + FW+ H G +T F+++ + + ++ G N + Sbjct: 332 TKKFWEDE---GIHGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKD 388 Query: 727 CLAILKGIFGSSAVPQ-PKE--------TVVSRWRADPWARGSYSYVAAGSSGNDYDLMA 777 C I+ I S + Q P+E +++ +W D +A G + + + Sbjct: 389 CADIV--INDLSLIHQLPREEIQTFCYPSMIQKWSLDKYAMGGITTFTP----YQFQHFS 442 Query: 778 QPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA---GRIADQ 828 + +T + R++FAGEHT + + + SGLR A R ++Q Sbjct: 443 ESLTAS---------VDRIYFAGEHTAEAH-GWIDSTIKSGLRAARDVNRASEQ 486 Score = 86.0 bits (211), Expect = 6e-17, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 96/238 (40%), Gaps = 44/238 (18%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGN--YVADLGAMVVTGLG 338 V+++G+G+SGL+AA L G VT+LEA +R GGRV T+R + A+LG M + Sbjct: 36 VVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLGPMRL--PE 93 Query: 339 GNPMAVV-SKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 + + ++ ++L + Q+ + + K E+ + D Sbjct: 94 KHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEV-----------------KKD 136 Query: 398 FNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKE 457 VL PV + + QL E+ + +E K+ + +LNK K Sbjct: 137 PGVLK-YPVKPSEEGKSAGQLYEESLGK-VVEELKRTNCSY-----ILNKYDTYSTK--- 186 Query: 458 LHQQYKEASEVKPPRDITAEFLVKS-----------KHRDLTALCKEYDELAETQGKL 504 KE + D+ + + + +H D+ A K +DE+ KL Sbjct: 187 -EYLLKEGNLSPGAVDMIGDLMNEDSGYYVSFPESLRHDDIFAYEKRFDEIVGGMDKL 243 >3KVE-A nrPDB Length = 486 Score = 254 bits (648), Expect = 1e-67, Method: Composition-based stats. Identities = 63/296 (21%), Positives = 115/296 (38%), Gaps = 44/296 (14%) Query: 548 SLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLD--IKLNTAVRQVRYTASGCEVIAV 605 SLKH DD F + + G +P ++ ++ +K N V +++ A+ V Sbjct: 220 SLKH---DDIFAYEKRFDEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVTVTYQ 276 Query: 606 NTRSTSQTFIYKCDAVL-CTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVL 664 T D V+ CT + +QF PPLP K A++ + + + K+ L Sbjct: 277 TPEK--DTSSNTADYVIVCTTSRAARR-----IQFEPPLPPKKQHALRSVHYRSGTKIFL 329 Query: 665 CFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIV 724 FW+ H G +T F+++ + + ++ G N + Sbjct: 330 TCSSKFWEDD---GIHGGKSTTDLPSRFIYYPNHNFSTGVGVIIAYGIGDDANFFQALKF 386 Query: 725 GRCLAILKGIFGSSAVPQ-PKE--------TVVSRWRADPWARGSYSYVAAGSSGNDYDL 775 C I+ S + Q PKE +++ +W D +A G+ + + Sbjct: 387 KDCADIV--FNDLSLIHQLPKEEIQSFCYPSMIQKWSLDKYAMGAITTFTP----YQFQR 440 Query: 776 MAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGL---REAGRIADQ 828 ++ +T P R+FFAGE+T + + + SGL R+ R ++Q Sbjct: 441 FSEALTA---------PQGRIFFAGEYTAEAH-GWIDSTIKSGLTAARDVNRASEQ 486 Score = 87.2 bits (214), Expect = 3e-17, Method: Composition-based stats. Identities = 56/258 (21%), Positives = 99/258 (38%), Gaps = 47/258 (18%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLG 338 V+++G+G+SGL+AA L G VT+LEA +R GGRV T R K + A+LG M + Sbjct: 36 VVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRNSKEGWYANLGPMRI--PE 93 Query: 339 GNPMAVV-SKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 + + ++ + L + Q+ + + K E+ D Sbjct: 94 KHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEV-----------------NKD 136 Query: 398 FNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKE 457 +L PV + + QL E+ + + + +LNK K Sbjct: 137 PGLLK-YPVKPSEEGKSAGQLYEESLGSAVKD------LKRTNCSYILNKYDTYSTK--- 186 Query: 458 LHQQYKEASEVKPPRDITAEF----------LVKS-KHRDLTALCKEYDELAETQGKLEE 506 KE + D+ + ++S KH D+ A K +DE+ G +++ Sbjct: 187 -EYLIKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIV---GGMDQ 242 Query: 507 KLQELEANPPSDVYLSSR 524 + V ++R Sbjct: 243 LPTSMYRAIEEKVKFNAR 260 >1O5W-A nrPDB Length = 534 Score = 223 bits (568), Expect = 3e-58, Method: Composition-based stats. Identities = 51/254 (20%), Positives = 94/254 (37%), Gaps = 34/254 (13%) Query: 581 GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFV 640 G +KL++ V + T V +N Y+C V+ +P + + + F Sbjct: 243 GDKVKLSSPVTYIDQTDDNIIVETLNHEH------YECKYVISAIPPILTAK----IHFK 292 Query: 641 PPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKA 700 P LP + +QR+ G + K ++ + FW + G E + L Sbjct: 293 PELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKK----DYCGCMIIEDEEAPIAITLDDT 348 Query: 701 ------PILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRAD 754 P ++ + A + + D+ + + + GS P W + Sbjct: 349 KPDGSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEE 408 Query: 755 PWARGSYS-YVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHG 813 ++ G Y+ Y G +M Q G I QP+ R++FAG T + + G Sbjct: 409 QYSGGCYTAYFPPG-------IMTQ---YGRVI---RQPVGRIYFAGTETATQWSGYMEG 455 Query: 814 ALLSGLREAGRIAD 827 A+ +G R A + + Sbjct: 456 AVEAGERAAREVLN 469 Score = 223 bits (567), Expect = 3e-58, Method: Composition-based stats. Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 24/203 (11%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNY-VADLGAMVVTGLG 338 V++IG G+SGLAAA+ L + ++V +LEARDRVGGR T R + D+G V G Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYV-GPT 81 Query: 339 GNPMAVVSKQVNMELAKIKQKCPLYEA-NGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 N + +SK++ +E K+ L + G+ P F + +Y LD Sbjct: 82 QNRILRLSKELGIETYKVNVNERLVQYVKGKTYP------FRGAFPPVWNPLAY----LD 131 Query: 398 FNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKE 457 +N L +G+ + V Q +H ++ W K+ +K+L++K+ K +E Sbjct: 132 YNNLWRTMDEMGKEIPVDAPWQARHAQE-----WDKMT-----MKDLIDKICWTKTA-RE 180 Query: 458 LHQQYKEASEVKPPRDITAEFLV 480 + + P +++A + + Sbjct: 181 FAYLFVNINVTSEPHEVSALWFL 203 >2COM-A nrPDB Length = 124 Score = 216 bits (549), Expect = 4e-56, Method: Composition-based stats. Identities = 115/124 (92%), Positives = 115/124 (92%), Gaps = 6/124 (4%) Query: 166 SEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNP 225 S EEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNP Sbjct: 5 SSGEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNP 64 Query: 226 KIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIG 285 KIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKT G Sbjct: 65 KIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKT------G 118 Query: 286 SGVS 289 SG S Sbjct: 119 SGPS 122 >2BK5-A nrPDB Length = 520 Score = 203 bits (516), Expect = 3e-52, Method: Composition-based stats. Identities = 60/302 (19%), Positives = 113/302 (37%), Gaps = 47/302 (15%) Query: 562 GSHLTVRNGYSCVPVALAE--GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCD 619 G G V + + G +KL V + T V +N +Y+ Sbjct: 205 GQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHE------MYEAK 258 Query: 620 AVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFG 679 V+ +P + + + F PPLP + + R+ G++ K ++ + FW Sbjct: 259 YVISAIPPTLGMK----IHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKK----D 310 Query: 680 HVGSTTASRGELFLFWNLYKA------PILLALVAGEAAGIMENISDDVIVGRCLAILKG 733 + G+ E + + L ++ + A + ++ + + + + Sbjct: 311 YCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAK 370 Query: 734 IFGSSAVPQPKETVVSRWRADPWARGSY-SYVAAGSSGNDYDLMAQPITPGPSIPGAPQP 792 + GS +P W + ++ G Y +Y G ++ Q G + QP Sbjct: 371 VLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPG-------ILTQ---YGRVL---RQP 417 Query: 793 IPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPR----QATP---GVP 845 + R++FAG T ++ + GA+ +G R A I L AM +P Q+ P VP Sbjct: 418 VDRIYFAGTETATHWSGYMEGAVEAGERAAREI----LHAMGKIPEDEIWQSEPESVDVP 473 Query: 846 AQ 847 AQ Sbjct: 474 AQ 475 Score = 176 bits (446), Expect = 4e-44, Method: Composition-based stats. Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 24/195 (12%) Query: 288 VSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNY-VADLGAMVVTGLGGNPMAVVS 346 +SG+AAA+ L G++V +LEARDRVGGR T R DLG V G N + ++ Sbjct: 14 ISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV-GPTQNRILRLA 72 Query: 347 KQVNMELAKIKQ-KCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKP 405 K++ +E K+ + + ++ G++ P F + +Y LD N Sbjct: 73 KELGLETYKVNEVERLIHHVKGKSYP------FRGPFPPVWNPITY----LDHNNFWRTM 122 Query: 406 VSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEA 465 +G+ + + E W + +KELL+K+ + K+L + Sbjct: 123 DDMGREIPSDAPWKA-----PLAEEWDNMT-----MKELLDKLCWTESA-KQLATLFVNL 171 Query: 466 SEVKPPRDITAEFLV 480 +++A + + Sbjct: 172 CVTAETHEVSALWFL 186 >2L3D-A nrPDB Length = 102 Score = 200 bits (507), Expect = 3e-51, Method: Composition-based stats. Identities = 100/101 (99%), Positives = 100/101 (99%) Query: 173 GVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFE 232 VEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFE Sbjct: 2 SVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFE 61 Query: 233 ATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPL 273 ATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPL Sbjct: 62 ATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPL 102 >3BI4-A nrPDB Length = 516 Score = 190 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 87/356 (24%), Positives = 131/356 (36%), Gaps = 85/356 (23%) Query: 536 LEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLD---IKLNTAVRQ 592 LE + LS K D F G + N Y V +A+ +KL+ V+ Sbjct: 171 LELWHGLDWKLLSAK----DTYFGHQGRNAFALN-YDSVVQRIAQSFPQNWLKLSCEVKS 225 Query: 593 VRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVL-------KQQPPAVQFVPPLPE 645 + S V T +Y D V+ T+P VL K ++F PPL Sbjct: 226 ITREPSK-NVTVNCEDGT----VYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLKP 280 Query: 646 WKTSAVQRMGFGNLNKVVLCFDRVFWD----------PSVNLFGHVGSTTASRGEL---- 691 A ++ FG L KV+ F+ W S N F + + EL Sbjct: 281 VIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSML 340 Query: 692 -----------------FLFWNLYKAP---ILLALVAGEAAGIMENISDDV--------- 722 F NL K+ + L+ +E+I +D Sbjct: 341 EREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQP 400 Query: 723 ---IVGRCL---AILKGI-----FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGN 771 + +CL ++ G+ ++ P + +VS W DP++RG+YS A G+ Sbjct: 401 VLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYS---ACFPGD 457 Query: 772 DYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIAD 827 D M ++ G R+ FAGEHTI + +GA SG REA RI+D Sbjct: 458 DPVDMVVAMSNGQD--------SRIRFAGEHTIMDGAGCAYGAWESGRREATRISD 505 Score = 88.7 bits (218), Expect = 8e-18, Method: Composition-based stats. Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 7/118 (5%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRK-GNYVADLGA 331 P KK KVIIIG+G++GL AA L G+ D +LEARDRVGGR+ T D+GA Sbjct: 6 PAKK--KVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGA 63 Query: 332 MVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEAT 389 NP+ + Q+++ + + E+ V+ + LLE Sbjct: 64 SWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNF---IYIDEERGRVDHDKELLLEIV 118 >3RHA-A nrPDB Length = 482 Score = 182 bits (462), Expect = 4e-46, Method: Composition-based stats. Identities = 67/278 (24%), Positives = 105/278 (37%), Gaps = 35/278 (12%) Query: 555 DDDFEFTGSHLTVRNGYSCVPVALAE--GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQ 612 D+DF V G V + A G D+ LN+ VR +++ +G V V+ R+T Sbjct: 203 DEDFILDKR---VIGGMQQVSLLQAAELGDDVVLNSPVRTIKWDENGVSV--VSERATV- 256 Query: 613 TFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWD 672 V+ +P + + V F PPLP + Q G + KV +D FW Sbjct: 257 ----NARFVIMAVPPNLYSR----VSFDPPLPRRQHQMHQHQSLGLVIKVHAVYDTPFWR 308 Query: 673 PSVNLFGHVGSTTASRGELFLFWNLYKA-PILLALVAGEAAGIMENISDDVIVGRCLAIL 731 L G S A E++ N + L+ V+ E A + +S + L + Sbjct: 309 EE-GLSGTGFSAGALVQEVYDNTNHGDSRGTLVGFVSDEKADAVFELSAEDRKKAILESI 367 Query: 732 KGIFGSSAVPQPKETVVSRWRADPWARGSY--SYVAAGSSGNDYDLMAQPITPGPSIPGA 789 G G A+ P+ S W ++ W RG+Y SY G D A Sbjct: 368 AGFLGDKALT-PEVYYESDWGSEEWTRGAYASSYDLGGLHRYGKDQHA------------ 414 Query: 790 PQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIAD 827 + ++++ V GA+ G A RI + Sbjct: 415 --NVGPIYWSSSDLAAEGYQHVDGAVRMGQATAARIVE 450 Score = 90.3 bits (222), Expect = 3e-18, Method: Composition-based stats. Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 12/157 (7%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 V+I+G+G SGL AAR+L+ G+ V +LEARDRVGGR T + ++G V+ Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGRTWTDTIDGAMLEIGGQWVS-PDQ 67 Query: 340 NPMAVVSKQVNMELA-KIKQKCPLY--------EANGQAVPKEKDEMVEQEFNRLLEATS 390 + + ++ +++ + + +Y + G P E + E ++L+ Sbjct: 68 TVLMELLDELGLKMYSRYRDGESVYIGADGKRTQYTGDTFPVN--ETTKAEMDKLVAILD 125 Query: 391 YLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQ 427 L+ ++ P + ++ DE+ Sbjct: 126 ELAAEIGPTEPWAHPKARELDTISFHHWLRQNSNDEE 162 >5IT3-A nrPDB Length = 85 Score = 170 bits (431), Expect = 2e-42, Method: Composition-based stats. Identities = 85/85 (100%), Positives = 85/85 (100%) Query: 183 LPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPY 242 LPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPY Sbjct: 1 LPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPY 60 Query: 243 NSDTVLVHRVHSYLERHGLINFGIY 267 NSDTVLVHRVHSYLERHGLINFGIY Sbjct: 61 NSDTVLVHRVHSYLERHGLINFGIY 85 >1SEZ-A nrPDB Length = 504 Score = 149 bits (376), Expect = 5e-36, Method: Composition-based stats. Identities = 106/571 (18%), Positives = 192/571 (33%), Gaps = 127/571 (22%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 +V +IG+GVSGLAAA +L+ G++VT+ EA + GG++ + + + D GA +T G Sbjct: 15 RVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTESEG 74 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEA------NGQAV--PKEKDEMVEQEFNRLLEATSY 391 + V+ ++ + KQ+ PL + NG V P ++++ F L S Sbjct: 75 D----VTFLIDSLGLREKQQFPLSQNKRYIARNGTPVLLPSNPIDLIKSNF---LSTGSK 127 Query: 392 LSHQLDFNVLNNKPVS-LGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVN 450 L L+ + NK +S + + E V ++H E +++ + + Sbjct: 128 LQMLLEPILWKNKKLSQVSDSHESVSGFFQRHFGKEVVDY---------LIDPFVAGTCG 178 Query: 451 LKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQE 510 +H + E + ++ + + L + KL K E Sbjct: 179 GDPDSLSMHHSFPE------------LWNLEKRFGSVI--------LGAIRSKLSPK-NE 217 Query: 511 LEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNG 570 + PP R R + G Sbjct: 218 KKQGPPKTSANKKRQRGSFSF------------------------------------LGG 241 Query: 571 YSCVPVALAEG---LDIKLNTAVRQVRYTASGCEV-----IAVNTRSTSQTFIYKCDAVL 622 + A+ + +++LN+ V ++ + + I + Q+ DAV+ Sbjct: 242 MQTLTDAICKDLREDELRLNSRVLELSCSCTEDSAIDSWSIISASPHKRQSEEESFDAVI 301 Query: 623 CTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFG--- 679 T PL +K A + P L + + + + L+ V+ F R + FG Sbjct: 302 MTAPLCDVKSMKIAKRGNPFL----LNFIPEVDYVPLSVVITTFKRENVKYPLEGFGVLV 357 Query: 680 ------HVGSTTASRGELFLFWNLYKAPILL--ALVAGEAAGIMENISDDVIVGRCLAIL 731 H T + +F + + L V G + S + + L Sbjct: 358 PSKEQQHGLKTLGTLFSSMMFPDRAPNNVYLYTTFVGGSRNRELAKASRTELKEIVTSDL 417 Query: 732 KGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQ 791 K + G+ P + W D L +I + Sbjct: 418 KQLLGAEGEPTYVNHLY--WSK---------AFPLYGHNYDSVL--------DAIDKMEK 458 Query: 792 PIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 +P LF+AG H +V AL SG A Sbjct: 459 NLPGLFYAGNH---RGGLSVGKALSSGCNAA 486 >2JB2-A nrPDB Length = 489 Score = 131 bits (328), Expect = 2e-30, Method: Composition-based stats. Identities = 91/561 (16%), Positives = 186/561 (33%), Gaps = 93/561 (16%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVT 335 K + V+++G G +GL +A +LQ G VT+LEAR R GGRV T R Sbjct: 9 KGSHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGRVWTARG------------- 55 Query: 336 GLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQ 395 G ++ +++ Y +P+ + ++ R L Sbjct: 56 GSEETDLSGETQKCTFSEGHF------YNVGATRIPQSHITL---DYCRELGVEIQGFGN 106 Query: 396 LDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKI 455 + N N + + V K + K Q L ++L++ K+ + Sbjct: 107 QNANTFVNYQSDTSLSGQSVTYRAAKADTFGYMSELLKKATDQGALDQVLSR--EDKDAL 164 Query: 456 KELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANP 515 E + + S+ R L + + YD + L Sbjct: 165 SEFLSDFGDLSD---------------DGRYLGSSRRGYDS------EPGAGLNFGTEKK 203 Query: 516 PSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHL--TVRNGYSC 573 P + R ++ F DF + + + T G Sbjct: 204 PFAMQEVIRSGIGRNFSF-----------------------DFGYDQAMMMFTPVGGMDR 240 Query: 574 VPVALAE---GLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVL 630 + A + +I V ++ + G V + D +CT+P ++ Sbjct: 241 IYYAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYT---AGGSKKSITADYAICTIPPHLV 297 Query: 631 KQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGE 690 + LP +A++ + K+ + + R +W+ ++G +T + Sbjct: 298 GRLQNN------LPGDVLTALKAAKPSSSGKLGIEYSRRWWETEDRIYGGASNTDKDISQ 351 Query: 691 LFLFWNLYKAPILLALV---AGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETV 747 + ++ Y + + + +G+ E+++ + + +A I G + Sbjct: 352 IMFPYDHYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEGSEIHGEKYTRDISSSF 411 Query: 748 VSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNY 807 WR ++ +++ A + P +P+ +++FAG+H + N Sbjct: 412 SGSWRRTKYSESAWANWAGSGGSHGG-------AATPEYEKLLEPVDKIYFAGDH-LSNA 463 Query: 808 PATVHGALLSGLREAGRIADQ 828 A HGAL S I ++ Sbjct: 464 IAWQHGALTSARDVVTHIHER 484 >4ZCC-A nrPDB Length = 336 Score = 107 bits (267), Expect = 2e-23, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGN 340 + IIG+G++GL+AA+ L S G V L + GGR+++ R D+GA T Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAGSLDMGAQYFTAR-DR 63 Query: 341 PMAVVSKQVNMELAKIKQKCP-LYEANGQAVPKEKDEMVEQEFNRLLEATSY 391 A KQ + + + P LY +G + DE V + A + Sbjct: 64 RFATAVKQWQAQ-GHVSEWTPLLYNFHGGRLSPSPDEQVRWVGEPGMSAITR 114 >5MOG-A nrPDB Length = 497 Score = 103 bits (257), Expect = 3e-22, Method: Composition-based stats. Identities = 99/571 (17%), Positives = 201/571 (35%), Gaps = 127/571 (22%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR-KGNYVADLGAM 332 PTK +V+I G+G++GL+ A+ L G LLEARD +GG++A ++ + + G Sbjct: 14 PTKPL-QVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETGLH 72 Query: 333 VVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYL 392 + G N + + + + K+ ++ A+P + E +F L A Sbjct: 73 IFFGAYPNIQNLFGELGINDRLQWKEHSMIF-----AMPNKPGEFSRFDFPETLPAPLNG 127 Query: 393 SHQLDFNVLNNKPVSLGQALEVVIQLQEKHVK-DEQIEHWKKIVKTQEELKELLNKMVNL 451 + NN+ ++ + ++ + L V +E ++ K+ + VN Sbjct: 128 IWA---ILRNNEMLTWPEKVKFALGLLPAMVGGQAYVEAQDGFTVSEWMKKQGVPDRVND 184 Query: 452 KEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQEL 511 + K + + P +++ + ++ + +R L Q K K+ L Sbjct: 185 EV----FIAMSKALNFIN-PDELSMQCILIALNRFL-------------QEKHGSKMAFL 226 Query: 512 EANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGY 571 + NPP + + D SL Sbjct: 227 DGNPPERLCMPIVD-------------------HVRSL---------------------- 245 Query: 572 SCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLK 631 G +++LN+ ++++ G V + + DA + P+ +LK Sbjct: 246 ---------GGEVRLNSRIQKIELNPDG----TVKHFALTDGTQITGDAYVFATPVDILK 292 Query: 632 QQPPAVQFVPPLPEWKT----SAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTAS 687 P EWK ++++ + V + FDR N + H+ + +S Sbjct: 293 LLVPQ--------EWKEISYFKKLEKLVGVPVINVHIWFDRKL----KNTYDHLLFSRSS 340 Query: 688 RGELF--------LFWNLYKAPILLALVAGEA-AGIMENISDDVIVGRCLAILKGIFGSS 738 ++ +++ ++ + L E G SD I+ + L +F Sbjct: 341 LLSVYADMSVTCKEYYDPNRSMLELVFAPAEEWVGR----SDTEIIEATMQELAKLFPDE 396 Query: 739 AVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFF 798 + + ++ R Y + P P PI + Sbjct: 397 IAADQSKAKILKYHVVKTPRSVYKTIPDCE---------------PCRPLQRSPIEGFYL 441 Query: 799 AGEHTIRNYPATVHGALLSGLREAGRIADQF 829 AG++T + Y A++ GA+LSG A + + + Sbjct: 442 AGDYTKQKYLASMEGAVLSGKLCAQSVVEDY 472 >3KKJ-A nrPDB Length = 336 Score = 103 bits (256), Expect = 4e-22, Method: Composition-based stats. Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGN 340 + IIG+G++GL+AA+ L + G V L + GGR+++ R D+GA T Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGALDMGAQYFTAR-DR 63 Query: 341 PMAVVSKQVNMELAKIKQKCP-LYEANGQAVPKEKDEMVEQEFNRLLEATSY 391 A KQ + + + P LY + + DE V + A + Sbjct: 64 RFATAVKQWQAQ-GHVAEWTPLLYNFHAGRLSPSPDEQVRWVGKPGMSAITR 114 >6CR0-A nrPDB Length = 440 Score = 93.0 bits (229), Expect = 6e-19, Method: Composition-based stats. Identities = 64/309 (20%), Positives = 99/309 (32%), Gaps = 61/309 (19%) Query: 534 ANLEFANATPLSTLS---------LKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEG--L 582 A L P + LS L WD + + V+ G + + A+ + Sbjct: 168 AELTLYGGAPTTELSYPSFVKFHALASWDTITFTDSEKRY-HVQGGTNALCQAIFDDCRA 226 Query: 583 DIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPP 642 D + V V T +G V + R +++ + TLP V V+F PP Sbjct: 227 DSEFGVPVEAVAQTDNGVTVTLADKR------VFRALTCVLTLPTKVYAD----VRFEPP 276 Query: 643 LPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTA------SRGELFLFWN 696 LP K + ++ L+ HV F Sbjct: 277 LPPEKRAFIEHAEMA---------------DGAELYVHVRQNLGNTFTFCDDPNPFNAVQ 321 Query: 697 LYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPW 756 Y L + G +++ + A ++ I G V + W D + Sbjct: 322 TYAYDDELGTILKITIGR-QSLINLENFDAIAAEIRKIHGDVEVLEALPY---NWAMDEY 377 Query: 757 ARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALL 816 AR SY + G Y MA+P RLFFAG T + + GA+ Sbjct: 378 ARTSYPAMRKGWFS-RYKDMAKP-------------ENRLFFAGSATADGWHEYIDGAIE 423 Query: 817 SGLREAGRI 825 SG+R I Sbjct: 424 SGIRVGREI 432 Score = 74.1 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 24/71 (33%), Positives = 37/71 (52%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 T+K I++G+G SGL AAR+L + G V ++EAR R+GGR ++G V Sbjct: 5 TEKIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVVNFLGRPVEIGGAGV 64 Query: 335 TGLGGNPMAVV 345 + A + Sbjct: 65 HWCQPHVFAEM 75 >2VVL-G nrPDB Length = 495 Score = 90.3 bits (222), Expect = 3e-18, Method: Composition-based stats. Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 259 HGLINFGIYK---RIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 G+ + G+ I+ VI+IG G GL A R L G LLEARDR+GG Sbjct: 17 QGVTSLGVISPPTNIEDTDKDGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGG 76 Query: 316 RVATFRKGNYVADLGAMVVT 335 R + Y ++G V Sbjct: 77 RSWSSNIDGYPYEMGGTWVH 96 Score = 68.3 bits (165), Expect = 2e-11, Method: Composition-based stats. Identities = 60/356 (16%), Positives = 107/356 (30%), Gaps = 69/356 (19%) Query: 492 KEYDELAETQGKLEEKLQELEANPPS------------DVYLSSRDRQILDWHFANLEFA 539 ++YDE++ ++ ++++ EL N S + SS + W + + Sbjct: 181 RKYDEMSYSE-RIDQIRDELSLNERSSLEAFILLCSGGTLENSSFGEFLHWWAMSGYTYQ 239 Query: 540 -NATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTAS 598 L + K D F G + VR V Sbjct: 240 GCMDCLMSYKFK----DGQSAFARRFWEEAAGTGRLGY--------VFGCPVRSVVNERD 287 Query: 599 GCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGN 658 V A + R + V+CT+PL VL +QF P L + SA+Q Sbjct: 288 AARVTARDGRE------FVAKRVVCTIPLNVLST----IQFSPALSTERISAMQAGHVSM 337 Query: 659 LNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLA----LVAGEAAGI 714 KV D T + L + + + G A Sbjct: 338 CTKVHAEVDNK---------DMRSWTGIAYPFNKLCYAIGDGTTPAGNTHLVCFGTDANH 388 Query: 715 MENISD-DVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDY 773 ++ D + + G FG + V W D +A+G++ + G Sbjct: 389 IQPDEDVRETLKAVGQLAPGTFGVKRL------VFHNWVKDEFAKGAWFFSRPGM----- 437 Query: 774 DLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQF 829 + G + + FA + + + GA+ G R A + ++ Sbjct: 438 --------VSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVLEEL 485 >3I6D-A nrPDB Length = 470 Score = 81.0 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 36/170 (21%), Positives = 69/170 (40%), Gaps = 20/170 (11%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQ------SFGMDVTLLEARDRVGGRVATFRKGNYVAD 328 + V+IIG G++GLAAA ++ + +++TL+EA RVGG++ T +K Y+ + Sbjct: 2 SDGKKHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKKDGYIIE 61 Query: 329 LGAMVVTGLGGNPMAVVSKQVNMELAKIKQ---------KCPLYEANGQAVPKEKDEMVE 379 G + + K + +E + L+ AV ++ Sbjct: 62 RGPDSFLERKKSA-PQLVKDLGLEHLLVNNATGQSYVLVNRTLHPMPKGAVMGIPTKIAP 120 Query: 380 QEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIE 429 L + +DF + P S + + + + + V DE +E Sbjct: 121 FVSTGLFSLSGKARAAMDFIL----PASKTKDDQSLGEFFRRRVGDEVVE 166 >2IVE-A nrPDB Length = 478 Score = 80.2 bits (196), Expect = 3e-15, Method: Composition-based stats. Identities = 23/66 (34%), Positives = 32/66 (48%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAM 332 +P V ++G G+SGLA A L+S G D LLE+ R+GG V T Y+ + G Sbjct: 11 MPRTTGMNVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGTHALAGYLVEQGPN 70 Query: 333 VVTGLG 338 Sbjct: 71 SFLDRE 76 >4DGK-A nrPDB Length = 501 Score = 78.7 bits (192), Expect = 1e-14, Method: Composition-based stats. Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 8/110 (7%) Query: 283 IIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGL--GGN 340 +IG+G GLA A +LQ+ G+ V LLE RD+ GGR + + D G V+T Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAIEE 65 Query: 341 PMAVVSKQVN--MELAKIKQKCPLYEANGQAV-PKEKDEMVE---QEFNR 384 A+ KQ+ +EL + L +G+ +E Q+FN Sbjct: 66 LFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNP 115 >4IV9-A nrPDB Length = 557 Score = 76.8 bits (187), Expect = 4e-14, Method: Composition-based stats. Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 21/136 (15%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKG----NYVADLG 330 T +V I+G+G+SGL AA +L G+ DV L E+RDR+GGRV + Y+A++G Sbjct: 36 TPTPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMG 95 Query: 331 AMVVTGLGGNPMAVVSK-------------QVNMELAKIKQKCPLYEANGQAVPKEKDEM 377 AM + K V+ EL ++ Y P E Sbjct: 96 AMRFPPSATGLFHYLKKFGISTSTTFPDPGVVDTELHYRGKR---YHWPAGKKPPELFRR 152 Query: 378 VEQEFNRLLEATSYLS 393 V + + LL L Sbjct: 153 VYEGWQSLLSEGYLLE 168 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 47/283 (16%), Positives = 87/283 (30%), Gaps = 34/283 (12%) Query: 560 FTGSHLTVRNGYSCVPVALA------EGLDIKLN-TAVRQVRYTASGCEVIAVNTRSTSQ 612 + + +G S + LA + L ++ + V ++ A + + Sbjct: 263 YQSDQRLIPDGISSLAARLADQSFDGKALRDRVCFSRVGRISREAEKIIIQT----EAGE 318 Query: 613 TFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWD 672 ++ D V+ T ++ L AV+ +K+ + FW Sbjct: 319 QRVF--DRVIVTSSNRAMQMIHCLTDSESFLSRDVARAVRETHLTGSSKLFILTRTKFWI 376 Query: 673 PSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVA-GEAAGIMEN--ISDDVIVGRC-- 727 + L + S RG L + P +V ++ RC Sbjct: 377 KN-KLPTTIQSDGLVRGVYCLDY-QPDEPEGHGVVLLSYTWEDDAQKMLAMPDKKTRCQV 434 Query: 728 ----LAILKGIFGSSAVPQPKET----VVSRWRADPWARGSYSYVAAGSSGNDYDLMAQP 779 LA + F S +P + + W DP + G++ G L QP Sbjct: 435 LVDDLAAIHPTFASYLLPVDGDYERYVLHHDWLTDPHSAGAFKLNYPGEDVYSQRLFFQP 494 Query: 780 ITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREA 822 +T +P L+ AG + GA+ + L A Sbjct: 495 MTA-----NSPNKDTGLYLAGCSCSFAG-GWIEGAVQTALNSA 531 >3NK2-X nrPDB Length = 431 Score = 74.5 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 51/288 (17%), Positives = 104/288 (36%), Gaps = 50/288 (17%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKG---NYVADLGAMVVT 335 I++G G SGL AAR L + G V LLE +R+GGR + ++G + Sbjct: 2 YDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLH 61 Query: 336 GLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFN-RLLEATSYLSH 394 +A + + A + G V+Q F EA + + Sbjct: 62 RKHHPRLAAELDRYGIPTAAASEFTSFRHRLGPT-------AVDQAFPIPGSEAVAVEAA 114 Query: 395 QLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEK 454 + +L A + + EK ++++ +E L E ++K+ +L Sbjct: 115 T--YTLLR-------DAHRIDL---EKGLENQDLEDLD------IPLNEYVDKL-DLPPV 155 Query: 455 IKELHQQYKEASEVKPPRDITAEFLVK---SKHRDLTALCKEYDEL-----AETQGKLEE 506 ++ + +P +A ++++ + H + + DE+ A+ + + Sbjct: 156 SRQFLLAWAWNMLGQPADQASALWMLQLVAAHHYSILGVVLSLDEVFSNGSADLVDAMSQ 215 Query: 507 KLQELEANPPSD--------VYLSSRDRQILDWHFANLEFANATPLST 546 ++ E+ V ++ +D H ATP++T Sbjct: 216 EIPEIRLQTVVTGIDQSGDVVNVTVKDGHAFQAH----SVIVATPMNT 259 Score = 70.2 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 58/350 (16%), Positives = 109/350 (31%), Gaps = 46/350 (13%) Query: 479 LVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEF 538 L++ HR E +L + L E + +L+ P S +L + W+ Sbjct: 118 LLRDAHRIDLEKGLENQDLEDLDIPLNEYVDKLDLPPVSRQFLLA-----WAWNMLGQPA 172 Query: 539 ANATPLSTLSLKHWDQDDDFEFTGSHLTV-RNGYSCVPVALAEGL-DIKLNTAVRQVRYT 596 A+ L L L S V NG + + A+++ + +I+L T V + + Sbjct: 173 DQASALWMLQLVAAHHYSILGVVLSLDEVFSNGSADLVDAMSQEIPEIRLQTVVTGIDQS 232 Query: 597 ASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGF 656 V ++ +V+ P+ ++ + F P LPE + S ++ Sbjct: 233 GDVVNVTVK------DGHAFQAHSVIVATPMNTWRR----IVFTPALPERRRSVIEEGHG 282 Query: 657 GNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIME 716 G K+++ + + G L+ + + ++ LL + Sbjct: 283 GQGLKILIHVRGA--EAGIECVGDGI-----FPTLYDYCEVSESERLLVAFTDSGS---- 331 Query: 717 NISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLM 776 D +G + V W ADP G + G Sbjct: 332 --FDPTDIGAVKDAVLYYLPEVEVLG---IDYHDWIADPLFEGPWVAPRVG--------- 377 Query: 777 AQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIA 826 +P R+ F G +P + GAL + I Sbjct: 378 ----QFSRVHKELGEPAGRIHFVGSDVSLEFPGYIEGALETAECAVNAIL 423 >3LOV-A nrPDB Length = 475 Score = 72.2 bits (175), Expect = 1e-12, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 38/54 (70%), Gaps = 2/54 (3%) Query: 280 KVIIIGSGVSGLAAARQLQSF--GMDVTLLEARDRVGGRVATFRKGNYVADLGA 331 +++I+G G++GLAAA + +++TLLEA +R+GG+VAT+R+ + + G Sbjct: 6 RLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGP 59 >5NMX-A nrPDB Length = 425 Score = 67.1 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 8/120 (6%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 +V ++G+G SGL AAR L+ G +V + E VGG + ++++ G V + + Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGG-TWNYTDETWMSEDGRPVYSSMYQ 61 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEA--TSYLSHQLD 397 N + K++ P ++ G VP ++ F + L H ++ Sbjct: 62 NLFVNLPKELMAFP-----DFPFHDIEGSYVPSKEVLKYFDNFTDAFDLRKLIKLQHHVE 116 >3WE0-A nrPDB Length = 580 Score = 63.7 bits (153), Expect = 4e-10, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 12/126 (9%) Query: 273 LPTKKTGK-VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK---GNYVAD 328 +P + G+ V I+G+G++GL AA +L G+ + EA ++GGR+ + +A+ Sbjct: 59 IPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEAS-KMGGRLRSQAFNGTDGIIAE 117 Query: 329 LGAMVVTGLGGNPMAVVSKQVNMELAKIKQ------KCPLYEANGQAVPKEKDEMVEQEF 382 LG M + ++ +E + + + GQ EK + F Sbjct: 118 LGGMRFP-VSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALF 176 Query: 383 NRLLEA 388 + +A Sbjct: 177 QEVTDA 182 Score = 55.6 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 39/193 (20%), Positives = 68/193 (35%), Gaps = 14/193 (7%) Query: 650 AVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGEL----FLFWNLYKAPILLA 705 A+ R + +K + DR FW G + L +LF N P ++ Sbjct: 374 ALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVIC 433 Query: 706 LVAGEAAGIMENISD--DVIVGRCLAILKGIFGSSAV--PQPKETVVSRWRADPWARGSY 761 L + ++ + + V L LK I+ + + + + W ADP G++ Sbjct: 434 LSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAF 493 Query: 762 SYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLRE 821 G + + A + P +F AG+ PA V GA+ + L Sbjct: 494 KGALPGHYRYNQRMYAHFMQA-----QMPVEQRGIFIAGDDVSWT-PAWVEGAVQTSLNA 547 Query: 822 AGRIADQFLGAMY 834 I + F G + Sbjct: 548 VWGIMNHFGGKTH 560 >4IVM-B nrPDB Length = 483 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 5/77 (6%) Query: 281 VIIIGSGVSGLAAARQLQSFGM--DVTLLEARDRVGGRVATFRK-GNYVADLGAMVV--T 335 V+++G G+SGLAA+ L V L+E+ +R+GG + + R + +LG + Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPGGIRPA 70 Query: 336 GLGGNPMAVVSKQVNME 352 G G ++ ++ ++ Sbjct: 71 GALGARTLLLVSELGLD 87 >3X0V-A nrPDB Length = 541 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 46/287 (16%), Positives = 91/287 (31%), Gaps = 44/287 (15%) Query: 567 VRNGYSCVPVALAEGL--DIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCT 624 + G S + A+ E L ++ N V + + ++ + + + V T Sbjct: 227 IEGGTSLLVDAMKETLVHKVQNNKRVEAISIDLDAPDDGNMSVKIGGKDYS-GYSTVFNT 285 Query: 625 LPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGST 684 LG L + L + A++ + + N KV L F +W + G+ Sbjct: 286 TALGCLDRMDLR---GLNLHPTQADAIRCLHYDNSTKVALKFSYPWWIKDCGITC-GGAA 341 Query: 685 TASRGEL---FLFWNLYKAPILLALVA---GEAAGIMENI---------SDDVIVGRCLA 729 + + +NL + L + + A + ++ +D +V L Sbjct: 342 STDLPLRTCVYPSYNLGDTGEAVLLASYTWSQDATRIGSLVKDAPPQPPKEDELVELILQ 401 Query: 730 ILKGIFGSSAVPQPKE------TVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPG 783 L + + + W DP G+++ G N Y + +P G Sbjct: 402 NLARLHAEHMTYEKIKEAYTGVYHAYCWANDPNVGGAFALFGPGQFSNLYPYLMRPAAGG 461 Query: 784 PSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFL 830 + GE + + H ++ L A QFL Sbjct: 462 -----------KFHIVGEASSVH-----HAWIIGSLESAYTAVYQFL 492 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 65/164 (39%), Gaps = 19/164 (11%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVT---LLEARDRVGGRVATFRKGNY---VADLGAMV 333 KV I+G+GVSGL A L + + E+ R GGR+ T + D+GAM Sbjct: 9 KVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFTDAKHDYYDIGAMR 68 Query: 334 VTG-LGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYL 392 + K+ M L K Y +G+ P ++ F Y+ Sbjct: 69 YPDIPSMKRTFNLFKRTGMPLIK-------YYLDGENTP----QLYNNHFFAKGVVDPYM 117 Query: 393 SHQLD-FNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIV 435 + V ++ S+G+ L+ ++ + ++ + + +++ Sbjct: 118 VSVANGGTVPDDVVDSVGEKLQQAFGYYKEKLAEDFDKGFDELM 161 >5JFC-L nrPDB Length = 474 Score = 56.4 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 15/116 (12%) Query: 212 FIRNRTLQLWLDNPKIQLTFEATLQ--QLEA---------PYNSDTVLVHR-VHSYLERH 259 +R +W DN +T Q Q E P N + R V Y H Sbjct: 79 AVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIG--KLERFVADYAREH 136 Query: 260 GLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 G+ + + + IK + + KV IIG+G +GL A L G +VT+ EA + GG Sbjct: 137 GIDDELLLEEIKGI-KRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG 191 Score = 35.6 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 1/64 (1%) Query: 249 VHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 ++ + +L R L+ + P K +V +IG G + + AAR G +V +L Sbjct: 265 IYSANEFLTRINLMKAYKFPE-YDTPIKVGKRVAVIGGGNTAMDAARSALRLGAEVWILY 323 Query: 309 ARDR 312 R R Sbjct: 324 RRTR 327 >5VJ7-A nrPDB Length = 476 Score = 56.4 bits (134), Expect = 6e-08, Method: Composition-based stats. Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 15/116 (12%) Query: 212 FIRNRTLQLWLDNPKIQLTFEATLQ--QLEA---------PYNSDTVLVHR-VHSYLERH 259 +R +W DN +T Q Q E P N + R V Y H Sbjct: 79 AVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIG--KLERFVADYAREH 136 Query: 260 GLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 G+ + + + IK + + KV IIG+G +GL A L G +VT+ EA + GG Sbjct: 137 GIDDELLLEEIKGI-KRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG 191 >3K30-A nrPDB Length = 690 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 19/123 (15%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 + +V+++G+G SGL AAR L G DV L EA +GGRV ++ G Sbjct: 388 KESDARVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRV--TQESALP---GLSAW 442 Query: 335 TGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSH 394 + AV+++ N+E+ + P D++VE F ++ AT + Sbjct: 443 GRVKEYREAVLAELPNVEIYRES-------------PMTGDDIVEFGFEHVITATG-ATW 488 Query: 395 QLD 397 + D Sbjct: 489 RTD 491 >4YRY-B nrPDB Length = 468 Score = 52.9 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 20/48 (41%), Positives = 27/48 (56%) Query: 268 KRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 + +KPL K KV ++GSG +GL AA L G V + EA + GG Sbjct: 130 EDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGG 177 >4MO2-B nrPDB Length = 368 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 58/165 (35%), Gaps = 17/165 (10%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL-GAMVVTGL 337 +I+GSG+ G A + G ++E R+ +GG T N GA + Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNCYTENIKNINVHKYGAHIFRTS 61 Query: 338 GGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 N + + Q C + KDE+ FN + S L Sbjct: 62 DQN-------IWD----YMNQFCEFNHFINSPIAIYKDEIYNLPFN--MNTFSKLWGIKT 108 Query: 398 FNVLNNKPVSLGQALEVVIQ--LQEKHVKDEQIEHWKKIVKTQEE 440 N K + + + + L+E+ + + ++K++K E Sbjct: 109 PNE-ARKIIEMQKQIIQHPPKNLEEQAISLVGTDVYEKLIKGYTE 152 >2GV8-A nrPDB Length = 447 Score = 50.2 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 41/114 (35%), Gaps = 12/114 (10%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQL--QSFGMDVTLLEARDRVGGRVATFRKGNYVADLG 330 LPT K+ IIG+G SGL A+ L + VTL E R GG V + Sbjct: 3 LPT--IRKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGG-VWNYTSTL------ 53 Query: 331 AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNR 384 + + NP+ V + PLY P E +Q F Sbjct: 54 SNKLPVPSTNPILTTEPIVGPAALPVYP-SPLYRDLQTNTPIELMGYCDQSFKP 106 >3KYB-A nrPDB Length = 390 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 26/46 (56%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK 322 K+ K++I+G+G SG RQL G V +++ RD +GG R Sbjct: 2 KSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARD 47 >5GJK-A nrPDB Length = 94 Score = 48.7 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 6/91 (6%) Query: 178 AFQSRLPHDRMTSQEAACFPDIISGPQQTQK--VFLFIRNRTLQLWLDNPKIQLTFEATL 235 ++ S ++ + E P+ +G +++ ++L RN + + NP+ LT A Sbjct: 7 SYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACR 66 Query: 236 QQLEAPYNSDTVLVHRVHSYLERHGLINFGI 266 + L D V RVH++LE+ GL+N+ + Sbjct: 67 RNLTG----DVCAVMRVHAFLEQWGLVNYQV 93 >3LXD-A nrPDB Length = 415 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 21/39 (53%), Positives = 25/39 (64%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVA 318 ++IG G GL AA L FG++VTLLEA RV RVA Sbjct: 154 NAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVA 192 >1PS9-A nrPDB Length = 671 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 27/49 (55%) Query: 268 KRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGR 316 ++ LP + + ++G+G +GLA A + G VTL +A +GG+ Sbjct: 363 TKMPILPAVQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQ 411 >5BR7-A nrPDB Length = 393 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 70/212 (33%), Gaps = 20/212 (9%) Query: 278 TGKVIIIGSGVSGLAAA-RQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL---GAMV 333 +I++GSG+ GL A R G V ++E R +GG + + ++ GA + Sbjct: 3 DFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHL 62 Query: 334 VTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKD--EMVEQEFNRLLEATSY 391 V VN A + ++ + + ++ Q F R Sbjct: 63 FHTSNK----RVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEA 118 Query: 392 LSHQLDFNVLNNKPVSLGQALEVVI----QLQEKHVKDEQIEHWKKIVKTQEELKELLNK 447 + + + + + + L E ++D + W Q + KEL Sbjct: 119 RELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQW------QTDPKELPAG 172 Query: 448 MVNLKEKIKELHQQYKEASEVKPPRDITAEFL 479 + +Y + P D A++L Sbjct: 173 NITRLPVRYNFDNRYFNDTYEGLPVDGYAQWL 204 >3RP7-A nrPDB Length = 407 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 7/112 (6%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR---VGGRVATF-RKGNYVADLGA 331 + K I+IG+G+ GL+AA L+ G+D + EA VG ++ + +A LG Sbjct: 21 QGHMKAIVIGAGIGGLSAAVALKQSGIDCDVYEAVKEIKPVGAAISVWPNGVKCMAHLGM 80 Query: 332 MVVTGLGGNPMAVVSKQVNMELAKIKQKC--PLYEANG-QAVPKEKDEMVEQ 380 + G P+ ++ + + Q PL E G + P + E+ + Sbjct: 81 GDIMETFGGPLRRMAYRDFRSGENMTQFSLAPLIERTGSRPCPVSRAELQRE 132 >4AP1-A nrPDB Length = 549 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR 321 + V+++G+G++GL A + +S G+ V EA VGG V + Sbjct: 19 TTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGG-VWYWN 63 >1V59-A nrPDB Length = 478 Score = 46.7 bits (109), Expect = 5e-05, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 K+ V+IIG G +G AA + G + +E R ++GG Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGG 42 >5MJK-A nrPDB Length = 327 Score = 46.7 bits (109), Expect = 5e-05, Method: Composition-based stats. Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK----GNYVADLG 330 T+K V+IIGSG +G+ AA M LLE R GG++ + Y +G Sbjct: 21 TEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLE-RGVPGGQMNNTAEIENYPGYETIMG 79 Query: 331 A 331 Sbjct: 80 P 80 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 8/86 (9%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG------RVATFRKGNYVADLGAMV 333 ++++IG G S + A L FG VT++ RD++ R K N++ D M Sbjct: 165 EILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPME 224 Query: 334 VTGLGGNPMAVVSKQVNMELAKIKQK 359 + G +VV K N++ ++ +K Sbjct: 225 IKGDDKKIQSVVYK--NVKTGEVTEK 248 >2Q7V-A nrPDB Length = 325 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV-ATFRKGNYV 326 PT V+IIG G +GL AA + +LE + GG++ + N+ Sbjct: 4 PTAHDYDVVIIGGGPAGLTAAIYTGRAQLSTLILE-KGMPGGQIAWSEEVENFP 56 >2CVJ-A nrPDB Length = 180 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 5/37 (13%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGR 316 VI++G G SGL+AA L G+ V +L+ GGR Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLD-----GGR 34 >5ZBC-A nrPDB Length = 451 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 42/115 (36%), Gaps = 12/115 (10%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQS----FGMDVTLLEARDRVGGRVATFRKGN-YVADLG 330 K + + I+G+G+SGL A L G+ + + + + GGR+ + +LG Sbjct: 22 KHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKMLDGKASIELG 81 Query: 331 AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRL 385 A G + + QK +Y + +++ N L Sbjct: 82 A-------GRYSPQLHPHFQSAMQHYSQKSEVYPFTQLKFKSHVQQKLKRAMNEL 129 >4REP-A nrPDB Length = 495 Score = 45.6 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 296 QLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGL--GGNPMAVVSKQVNMEL 353 +L+ G VT+ E D GG++ K Y DLG + T N A+ +++ Sbjct: 19 RLRHQGYSVTIFEKNDYAGGKLHAIEKDGYRFDLGPSLFTLPHLVENLFALFPEEIIDFG 78 Query: 354 AKIK 357 K K Sbjct: 79 YKSK 82 >4Y4N-A nrPDB Length = 286 Score = 45.6 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 17/29 (58%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 V I+G G SGL AAR + G V +LE Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLE 82 >4UIR-A nrPDB Length = 646 Score = 45.6 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 56/286 (19%), Positives = 103/286 (36%), Gaps = 25/286 (8%) Query: 265 GIYKRIKPLPTKK--TGKVIIIGSGVSGLAAARQLQSFGM----DVTLLEARDRVGGRV- 317 G Y+R K +P + K+ IIGSG++G++AA G ++T LE GG + Sbjct: 47 GNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSLD 106 Query: 318 -ATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMEL---AKIKQKCPLYEANGQAVPKE 373 A Y+ G + N + +E+ + + L N K Sbjct: 107 GAGNPTDGYII-RGGREMDMTYENLWDMFQDIPALEMPAPYSVLDEYRLINDNDSNYSKA 165 Query: 374 KDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKK 433 + + E + QL L K L + E +K W+ Sbjct: 166 RLINNKGEIKDFSKFGLNKMDQLAIIRLLLKNKEELDDLTIEDYFSESFLKSNFWTFWRT 225 Query: 434 IVKTQE-----ELKELLNKMVNLKEKIKELHQQ-YKEASE----VKPPRDITAEFLVKSK 483 + + ELK +++ ++ + + +L + + ++ V P R E K Sbjct: 226 MFAFENWHSLLELKLYMHRFLHAIDGLNDLSSLVFPKYNQYDTFVTPLRKFLQE---KGV 282 Query: 484 HRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQIL 529 + L L K+ D T+GK+ E + + + + D I+ Sbjct: 283 NIHLNTLVKDLDIHINTEGKVVEGIITEQDGKEVKIPVGKNDYVIV 328 >4Y4M-A nrPDB Length = 290 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 18/29 (62%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 V+I+G+G SGL AR L G V +LE Sbjct: 61 DVVIVGAGPSGLTCARYLAKEGFKVVVLE 89 >3MJ4-A nrPDB Length = 397 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 11/100 (11%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTG 336 K +I+G+G +G A +L S G V +++ R +GG V + Sbjct: 28 KGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYDDAGVL------IHP 81 Query: 337 LGGNPMAVVSKQVNMELAKIKQKCP-----LYEANGQAVP 371 G + SK V L++ + P L +GQ +P Sbjct: 82 YGPHIFHTNSKDVFEYLSRFTEWRPYQHRVLASVDGQLLP 121 >4C5O-A nrPDB Length = 357 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 V++IG G SGL+A L+ G+ +L+A GG Sbjct: 5 DVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGG 40 >3ATQ-A nrPDB Length = 453 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 2/44 (4%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARD--RVGGR 316 + V+IIG G +G +AA QL G+ + L++++ R+G + Sbjct: 3 KELKYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDK 46 >4OVI-A nrPDB Length = 542 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR 321 V+++G+G SGL A +L+ G V ++E VGG V + Sbjct: 18 DVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG-VWYWN 58 >5TWC-A nrPDB Length = 344 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGA 331 V IIG G SGL A+ M V L++ + +GG++ + + D+G Sbjct: 3 DVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIY-PEKIIWDIGG 53 >6GAR-A nrPDB Length = 349 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGA 331 + ++ V +IG G +GL +A M ++E +GG++ + + D+G Sbjct: 1 MNREELFDVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPHLGGKIHVY-PEKMIWDVGG 58 >3FG2-P nrPDB Length = 404 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329 +P KK V++IG+G GL A ++ G++V ++E RV RV T +Y D Sbjct: 139 MPDKKH--VVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVTPEISSYFHDR 193 >1I8T-A nrPDB Length = 367 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 57/167 (34%), Gaps = 20/167 (11%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL-GAMVVTGL 337 II+GSG+ G A +L+ V ++E R+ +GG T GA + Sbjct: 2 YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFH-- 59 Query: 338 GGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 + + + + KD++ FN + + D Sbjct: 60 TNDKY-----IWD----YVNDLVEFNRFTNSPLAIYKDKLFNLPFN--MNTFHQMWGVKD 108 Query: 398 F----NVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEE 440 N++N + G + L+E+ + + ++ ++K E Sbjct: 109 PQEAQNIINAQKKKYGDKVPE--NLEEQAISLVGEDLYQALIKGYTE 153 >4X4J-A nrPDB Length = 507 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 272 PLPTKKTGK--VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVAD 328 +P V+I G+G +GL A +L+ G+ V +LE R+ R R + A Sbjct: 14 LVPRGSHMDAPVVIAGAGPAGLMLAGELRLAGIGVVVLE---RLPARTGESRGLGFTAR 69 >3UKH-A nrPDB Length = 519 Score = 43.3 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 280 KVIIIGSGVSGLAAARQL-QSFGMDVTLLEARDRVGGRVAT-FRKGNYVADLGAMVV 334 V++IG+G +GL AA++L Q G ++++ + GG +T ++ D+G V+ Sbjct: 8 DVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVTPEGFLYDVGGHVI 64 >2VOU-A nrPDB Length = 397 Score = 43.3 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 33/95 (34%), Gaps = 17/95 (17%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV-----GGRVATFRKGNYVADLGA 331 T ++ ++G +SGL AA L+ G+DV + E + G V +Y+ + G Sbjct: 4 TTDRIAVVGGSISGLTAALMLRDAGVDVDVYERSPQPLSGFGTGIVVQPELVHYLLEQGV 63 Query: 332 ------------MVVTGLGGNPMAVVSKQVNMELA 354 V L G + V Sbjct: 64 ELDSISVPSSSMEYVDALTGERVGSVPADWRFTSY 98 >2TMD-A nrPDB Length = 729 Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 17/41 (41%), Positives = 24/41 (58%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 TK V+I+G+G SG AAR L G V L + +++GG Sbjct: 386 TKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGG 426 >1RP0-A nrPDB Length = 284 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 280 KVIIIGSGVSGLAAARQLQSFG-MDVTLLEARDRVGGRVA 318 V+++G+G +GL+AA ++ + V ++E GG Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW 80 >3UP5-A nrPDB Length = 545 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR 321 ++IG+GV+G+ A + GM V +EA + VGG + Sbjct: 6 KSPALDAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGG-TWYWN 51 >5UTH-A nrPDB Length = 319 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 21/52 (40%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYV 326 ++ VIIIGSG +G AA + + E G + T NY Sbjct: 12 SQTVHDVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGGALMTTTEVENYP 63 >4EMJ-A nrPDB Length = 410 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 6/85 (7%) Query: 260 GLINFGIYKRIKPLPT--KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARD----RV 313 G++ Y ++ L +++I+G G+ G A + G+ VT+LEA D RV Sbjct: 123 GVVTLRTYGDVQVLRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRV 182 Query: 314 GGRVATFRKGNYVADLGAMVVTGLG 338 GR + +LG V G G Sbjct: 183 LGRRIGAWLRGLLTELGVQVELGTG 207 >5TUK-A nrPDB Length = 408 Score = 42.5 bits (98), Expect = 9e-04, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 67/184 (36%), Gaps = 19/184 (10%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLE--ARDRVGGRVATFRKGNYVADLGAMVVT 335 K+++IG+G++G A L+ FG L+E A R GG DL + Sbjct: 25 INKILVIGAGIAGPAVCYWLRRFGFSPILVERCANLRKGG--HAVDIRGVAIDLAKSM-- 80 Query: 336 GLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAV---PKEKDEMVEQEFNRLLEATSYL 392 + + QV + + L+E G+ + E++ + ++L + Sbjct: 81 -GIYKKICNMRTQVELGRYVDAEGNILHEEKGERFGFREGDDIEILRGDLVQIL-IDAMG 138 Query: 393 SHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLK 452 FN +EV KD + E + +V + L +MV K Sbjct: 139 DVPCHFNQWVESIKQRDNDVEV-------QFKDGRTELYD-LVIGADGLHSTTRRMVFDK 190 Query: 453 EKIK 456 ++ K Sbjct: 191 DEYK 194 >4JDR-A nrPDB Length = 474 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 27/43 (62%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 + T+ +V+++G+G +G +AA + G++ ++E + +GG Sbjct: 1 MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGG 43 >3LZX-A nrPDB Length = 332 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 6/104 (5%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVT 335 K + IIG G GL A V ++E+ ++GG+++ Y+ D V Sbjct: 5 TKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYD-----VA 59 Query: 336 GLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVE 379 G + + ++AK Q L +A ++V K+ D + + Sbjct: 60 GFPKIRAQELINNLKEQMAKFDQTICLEQAV-ESVEKQADGVFK 102 >6GAS-A nrPDB Length = 331 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 29/62 (46%) Query: 270 IKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329 +K +K + IIG G +GL A V ++E+ ++GG+++ Y+ D+ Sbjct: 1 MKVAENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDV 60 Query: 330 GA 331 Sbjct: 61 AG 62 >3JSK-A nrPDB Length = 344 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 280 KVIIIGSGVSGLAAARQLQSF--GMDVTLLEARDRVGGRVA 318 ++I+G+G GL+AA L + + +T++EA GG Sbjct: 81 DIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW 121 >3BHF-A nrPDB Length = 390 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 29/82 (35%), Gaps = 5/82 (6%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV---GGRVATFRKGNYVADLGAMV 333 VI++G+G G+AA QL G+ L++A D G + + G Sbjct: 3 THFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREY 62 Query: 334 VTGLGGNPMAVVSKQVNMELAK 355 V + ++ E Sbjct: 63 V--PLALRSQELWYELEKETHH 82 >4GCM-A nrPDB Length = 312 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK 322 T+ + IIG+G +G+ AA + ++E R GG++A + Sbjct: 3 TEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIE-RGIPGGQMANTEE 49 >2GAG-B nrPDB Length = 405 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 11/83 (13%) Query: 272 PLPTKKTGKVIIIGSGVSGLAAARQL-QSFGM-DVTLLEARDRVGGRVA---TFRKGNYV 326 P P KK+ II+G G GLA A L ++ G+ +V +LE GG +A T + NY+ Sbjct: 16 PEP-KKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYL 74 Query: 327 ADLGAMVVTGLGGNPMAVVSKQV 349 D A + + +Q+ Sbjct: 75 WDESAGIYE-----KSLKLWEQL 92 >2DCE-A nrPDB Length = 111 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%) Query: 161 EEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQ-QTQKVFLFIRNRTLQ 219 EEE PE+ + + + + +E P+ G Q +T + +L IRN L Sbjct: 9 EEEELKPPEQ---------EIEIDRNIIQEEEKQAIPEFFEGRQAKTPERYLKIRNYILD 59 Query: 220 LWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIK 271 W L + L+ + + + R+H+YLE G INFG + + Sbjct: 60 QWEICKPKYLNKTSVRPGLKNCGDVNCI--GRIHTYLELIGAINFGCEQAVY 109 >5XHU-A nrPDB Length = 329 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 338 V IIG G GL A + ++E ++GG+V+ F + D+G + G+ Sbjct: 3 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIRDIGG--IPGIA 60 Query: 339 GNPMAVVSKQ 348 G + K+ Sbjct: 61 GKQLIEQLKE 70 >4K22-A nrPDB Length = 365 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 15/31 (48%), Positives = 19/31 (61%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 V I+G G+ GLA A LQ G+ V +LE R Sbjct: 5 DVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >1ZOV-A nrPDB Length = 386 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 28/82 (34%), Gaps = 5/82 (6%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV---GGRVATFRKGNYVADLGAMV 333 VI++G+G G+AA L G+ L+++ D G R + G Sbjct: 2 THFDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREY 61 Query: 334 VTGLGGNPMAVVSKQVNMELAK 355 V + ++ E Sbjct: 62 V--PFALRAQELWYELEKETHH 81 >3FPZ-A nrPDB Length = 326 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 280 KVIIIGSGVSGLAAARQLQSF--GMDVTLLEARDRVGGRVA 318 VII+G+G SGL+AA + + V ++E+ GG Sbjct: 67 DVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSW 107 >6O85-E nrPDB Length = 523 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 57/248 (22%), Positives = 87/248 (35%), Gaps = 64/248 (25%) Query: 42 AGLSGPAEVGPGAVGERTPRKKE----------------PPRASPPGGLAEPPGSAGPQA 85 +G+ GPGAVG ++++ A P G A +A Q Sbjct: 14 SGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSA--VSAAQCQV 71 Query: 86 GPT-VVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAK 144 GPT +P S + T + P GR +K E R +E E ER K Sbjct: 72 GPTRELPESGIQLGTPREKVPAGR-------SKAELR---------AERRAKQEAERALK 115 Query: 145 AEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPH----DRMTSQEAACFPDII 200 ++ + PPP+A P + E PSGV+ RLP D + + P+ Sbjct: 116 QARKGEQGGPPPKASP----STAGETPSGVK------RLPEYPQVDDLLLRRLVKKPERQ 165 Query: 201 SGPQQT---QKVFLF------IRNRTLQLWLDNPKIQLTFEAT---LQQLEAPY---NSD 245 P + KV LF R +L ++ P + LQ + N+ Sbjct: 166 QVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNAR 225 Query: 246 TVLVHRVH 253 + + R Sbjct: 226 CIALLRAL 233 >1DOD-A nrPDB Length = 394 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEAR--DRVGGRVATFRKGNYVADL 329 +V IIG+G SGL + L G+D +LE + D V GR+ + DL Sbjct: 4 QVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDL 55 >5Z70-A nrPDB Length = 605 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 6/54 (11%) Query: 283 IIGSGVSGLAAARQL----QSFGMDVTLLEARDRVGGRV--ATFRKGNYVADLG 330 IIGSG++GLA+A L + G D+T+L+A GG + + + Y+ G Sbjct: 9 IIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSLDGSGNAEDGYLIRGG 62 >5Y77-A nrPDB Length = 473 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 43/111 (38%), Gaps = 14/111 (12%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV----GGRVATFRKGNYVADLG 330 T +V IIG+G++G AR L G V L E R G R + +A+ G Sbjct: 5 TDNARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLA--LAERG 62 Query: 331 AMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQE 381 A + +A + ++V E ++ + + G + + E Sbjct: 63 AHAL------RLAGLEREVLAEAVMMRGR--MVHVPGTPPNLQPYGRDDSE 105 >5L46-A nrPDB Length = 841 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 282 IIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVA 318 +IIG G G++ A L GM DV LLE + G Sbjct: 26 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 63 >4ZN0-A nrPDB Length = 311 Score = 41.0 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVA 318 +IIIG G +GL A +G+D +LE R+ + G+++ Sbjct: 8 YDLIIIGGGPAGLTAGIYAVRYGLDTLILE-RNEISGQIS 46 >4A6N-B nrPDB Length = 398 Score = 41.0 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 265 GIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEA-RDR----VGGRVAT 319 G+ R + V IIG G GL A+ LQ G+DV++ E DR GG + Sbjct: 13 GLVPRGSHMNLLSDKNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGTLDL 72 Query: 320 FRKGN 324 + Sbjct: 73 HKGSG 77 >4P9S-A nrPDB Length = 848 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 272 PLPTKKTGKV--IIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVA 318 P P + + +IIG G G++ A L GM DV LLE + G Sbjct: 15 PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 64 >1NAA-A nrPDB Length = 541 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 4/49 (8%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVA 327 II+G+G G+ AA +L G V LLE GG G YVA Sbjct: 3 YDYIIVGAGPGGIIAADRLSEAGKKVLLLER----GGPSTKQTGGTYVA 47 >6CMZ-A nrPDB Length = 466 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 + +++IG G G AA + G+ L+E RDR+GG Sbjct: 5 KNEHTTLLVIGGGPGGYVAAIRAGQLGIPTVLVE-RDRLGG 44 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 24/40 (60%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 P +++++G+G GL + G+DV+++EA +RV Sbjct: 174 PATLPKRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERV 213 >3QJ4-A nrPDB Length = 342 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 58/147 (39%), Gaps = 17/147 (11%) Query: 280 KVIIIGSGVSG-LAAA--RQLQSFGMDVTLLEARDRVGGRVATF---RKGNYVADLGAMV 333 +V+I+G+G++G L AA R+ S + + + + D GGR+ T ADLGA Sbjct: 3 QVLIVGAGMTGSLCAALLRRQTSGPLYLAVWDKADDSGGRMTTACSPHNPQCTADLGAQY 62 Query: 334 VTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKD---------EMVEQEFNR 384 +T A ++ EL PL V KE D + + + + Sbjct: 63 ITCTPH--YAKKHQRFYDELLAYGVLRPLSSPIEGMVMKEGDCNFVAPQGISSIIKHYLK 120 Query: 385 LLEATSYLSHQLDFNVLNNKPVSLGQA 411 A Y H++ L + + + Sbjct: 121 ESGAEVYFRHRVTQINLRDDKWEVSKQ 147 >5EZ7-A nrPDB Length = 392 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAM 332 +P + ++I+G G++GL +L+ G L+E+ GG + + + GA Sbjct: 2 MPQALSTDILIVGGGIAGLWLNARLRRAGYATVLVESASLGGG--QSVKSQG-IIHGGAK 58 Query: 333 V 333 Sbjct: 59 Y 59 >2NVK-X nrPDB Length = 488 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 58/159 (36%), Gaps = 15/159 (9%) Query: 260 GLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVAT 319 G + +GI ++ GK +++G+G GL A L+ G + T++ V + Sbjct: 169 GAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVM---------VRS 219 Query: 320 FRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVE 379 + + +V + + + K V + + K L + +E +++ + Sbjct: 220 IVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDVYD 279 Query: 380 QEFNRLLEATSYLSHQLDFNVLNNKPVSL-GQALEVVIQ 417 L +D L N V++ + V Q Sbjct: 280 ---TVLWAIGRKG--LVDDLNLPNAGVTVQKDKIPVDSQ 313 Score = 34.4 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 272 PLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 P+ +I+IG G +GLA A++ G V L+ Sbjct: 3 PVQGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLD 39 >3IHG-A nrPDB Length = 535 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 21/34 (61%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 V+++G+G+ GL+ A L G+ V ++E R + Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVERRPGL 40 >1F6M-A nrPDB Length = 320 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 T K K++I+GSG +G AA + L+ ++ G T N+ D + Sbjct: 2 TTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGD--PNDL 59 Query: 335 TGLG 338 TG Sbjct: 60 TGPL 63 >5YGQ-A nrPDB Length = 342 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL-GAMVVTG 336 V+I+G+G GL A +L + L++ D+VGG+ A + D+ G +VTG Sbjct: 8 DVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIYDIPGIPMVTG 65 >6BRD-A nrPDB Length = 476 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 19/34 (55%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 VI++G G +GL A +L+ G+ V +LE Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEP 36 >6J0Z-C nrPDB Length = 491 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 20/33 (60%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEA 309 V+++G+G +GL A +L+ G+ V +L+ Sbjct: 4 YDSDVVVVGAGPTGLMLAGELRLAGVSVVVLDK 36 >4RPJ-A nrPDB Length = 399 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 52/168 (30%), Gaps = 12/168 (7%) Query: 274 PTKKTGKVIIIGSGVSGLAAA-RQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL--- 329 P + ++GSG GL A R V +LE R +GG + + ++ Sbjct: 3 PMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKY 62 Query: 330 GAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVP-KEKDEMVEQEFNRLLEA 388 GA + V + + + + NGQA +V Q F + Sbjct: 63 GAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAM---HNGQAYQFPMGLGLVSQFFGKYFTP 119 Query: 389 TSYLSHQLDFNVLNNKPVSLGQALEVVI----QLQEKHVKDEQIEHWK 432 + + + + + L E VK + W+ Sbjct: 120 EQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQ 167 >5TUM-A nrPDB Length = 410 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE--ARDRVGGRVATFRK 322 K K+++IG+GV+G A L+ FG L+E A R GG+ R Sbjct: 24 KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRG 71 >1NHQ-A nrPDB Length = 447 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 3/68 (4%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK--GNYVADLGAMVVTG 336 V++IGSG G+ AA G VT+++ DR G V ++ ++ A +T Sbjct: 150 NNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLG-VYLDKEFTDVLTEEMEANNITI 208 Query: 337 LGGNPMAV 344 G + Sbjct: 209 ATGETVER 216 >3R9U-A nrPDB Length = 315 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 21/43 (48%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK 322 V IIG G +GL+A G+ ++ + GG++ + + Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSE 48 >2E5V-A nrPDB Length = 472 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 2/50 (4%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG 330 + IIGSG++GL+A L+ G VTL+ R+ G KG A +G Sbjct: 2 IYIIGSGIAGLSAGVALRRAGKKVTLI--SKRIDGGSTPIAKGGVAASVG 49 >5W4C-A nrPDB Length = 371 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Query: 263 NFGIY--KRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 +FG+ KR + K KV+IIGSG G AA L ++ L E Sbjct: 13 SFGVREPKRTGEVSKKMHSKVVIIGSGPGGHTAAIYLARANLEPVLYE 60 >6DLL-A nrPDB Length = 398 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 38/93 (40%), Gaps = 2/93 (2%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEAR--DRVGGRVATFRKGNYVADLGAMVVTGL 337 +V IIG+G SGL + L G+D ++E + + V GR+ DL Sbjct: 7 QVAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQGTVDLLREAGVAE 66 Query: 338 GGNPMAVVSKQVNMELAKIKQKCPLYEANGQAV 370 + +V + V + + +Q+ L G Sbjct: 67 RMDREGLVHEGVELLVGGRRQRLDLKALTGGKT 99 >4C3X-A nrPDB Length = 530 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 19/36 (52%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 V+++GSG L A + G+ +LE DR GG Sbjct: 29 DVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGG 64 >5TUL-A nrPDB Length = 406 Score = 39.4 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 9/59 (15%) Query: 271 KPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329 +P K K+++IG+ ++G A L +G TL+E + + RKG Y DL Sbjct: 20 HMMPHTK--KILVIGASIAGPALCYWLNHYGFQPTLVE-------KNQSTRKGGYAIDL 69 >2QA2-A nrPDB Length = 499 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVAD 328 VI++G+G +GL A +L+ G+DV +LE + R R + A Sbjct: 14 SVIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQ---RTGESRGLGFTAR 59 >2FQ3-A nrPDB Length = 104 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 39/86 (45%), Gaps = 6/86 (6%) Query: 186 DRMTSQEAACFPDIISG--PQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYN 243 +++ S E P+ + P +T +V++ RN + + NP + + + Sbjct: 23 EKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSG--- 79 Query: 244 SDTVLVHRVHSYLERHGLINFGIYKR 269 D + R+H +L + GLIN+ + + Sbjct: 80 -DAAALFRLHKFLTKWGLINYQVDSK 104 >5ZYN-B nrPDB Length = 471 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 14/118 (11%) Query: 281 VIIIGSGVSGLAAARQL-QSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 V++IGSG++GL + +L + + V LL+ +GG G GA T Sbjct: 7 VVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGI----NGA--HTDTQQ 60 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLD 397 N + + ++ + K L+ A G+ VP D++ ++ + + + +LD Sbjct: 61 NLKVMDTPELFL-------KDTLHSAKGRGVPSLMDKLTKESKSAIRWLQTEFDLKLD 111 >3AB1-A nrPDB Length = 360 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 274 PTKKTGK---VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG 330 P + IIG G +G+ AA Q + ++E+ ++GG++A ++ D+ Sbjct: 7 PATDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYDVA 66 Query: 331 A 331 Sbjct: 67 G 67 >2EQ6-A nrPDB Length = 464 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 KT +I+IG+G G AA + G+ V +EA + VGG Sbjct: 5 KTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGE-VGG 42 >2ZBW-A nrPDB Length = 335 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 24/54 (44%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGA 331 V+I+G+G +GL A + G+ ++ GG++ Y+ D+ Sbjct: 5 HTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALYPEKYIYDVAG 58 >2RGJ-A nrPDB Length = 402 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 45/133 (33%), Gaps = 15/133 (11%) Query: 280 KVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG 338 ++I G+G+ GL+ A L G+ VTLLE+ + R ++ V L Sbjct: 6 DILIAGAGIGGLSCALALHQAGIGKVTLLESSSEI-------RPLGVGINIQPAAVEALA 58 Query: 339 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDF 398 + + +++ + +G V E + S +L Sbjct: 59 ELGLGPALAATAIPTHELR----YIDQSGATVWSEPRGVEAGNAYPQY---SIHRGELQM 111 Query: 399 NVLNNKPVSLGQA 411 +L LGQ Sbjct: 112 ILLAAVRERLGQQ 124 >4B1B-A nrPDB Length = 542 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 17/33 (51%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 ++IG G G+A+A++ + G V L + Sbjct: 40 TYDYDYVVIGGGPGGMASAKEAAAHGARVLLFD 72 >2GMH-A nrPDB Length = 584 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 6/41 (14%) Query: 280 KVIIIGSGVSGLAAARQL------QSFGMDVTLLEARDRVG 314 V+I+G+G +GL+AA +L + V L+E +G Sbjct: 37 DVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIG 77 >2YQU-A nrPDB Length = 455 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 +++IG+G G AA + GM V ++E +GG Sbjct: 2 YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGG 38 Score = 34.0 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 19/34 (55%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 ++I++G GV GL G +V +LE DR+ Sbjct: 169 RLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRI 202 >2A87-A nrPDB Length = 335 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTG 336 VI+IGSG +G AA + + E G + T NY +TG Sbjct: 13 PVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNG--ITG 70 Query: 337 LG 338 Sbjct: 71 PE 72 >3GMC-A nrPDB Length = 415 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTG 336 KT + + G G +GL AA L+ G DV L E + F G Y+ G V+ G Sbjct: 46 KTRRAEVAGGGFAGLTAAIALKQNGWDVRLHEKSSEL----RAFGAGIYLWHNGLRVLEG 101 Query: 337 LG 338 LG Sbjct: 102 LG 103 >4YNU-A nrPDB Length = 571 Score = 38.3 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFG-MDVTLLEARDRVGGRVATFRKGNYVADLGAMV 333 T I++G G SGL A +L + V LLEA V Y G+ + Sbjct: 3 TTTYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAGASVFNNPDVTNANGYGLAFGSAI 61 >2R9Z-A nrPDB Length = 463 Score = 38.3 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 27/49 (55%) Query: 265 GIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 GI ++ +V IIG+G G+ A L+SFG +VT++ DR+ Sbjct: 153 GITSDGFFALQQQPKRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRL 201 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 + +I IG G GLA A + +FG V L+E++ +GG Sbjct: 2 TQHFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKA-LGG 40 >1LVL-A nrPDB Length = 458 Score = 38.3 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 47/135 (34%), Gaps = 18/135 (13%) Query: 266 IYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNY 325 I P ++++G G GL + G V+++EAR+R+ + T+ Sbjct: 159 ISSTEALAPKALPQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERI---LPTYDSE-- 213 Query: 326 VADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRL 385 P+A K++ + L + YE K + E +R+ Sbjct: 214 ------------LTAPVAESLKKLGIAL-HLGHSVEGYENGCLLANDGKGGQLRLEADRV 260 Query: 386 LEATSYLSHQLDFNV 400 L A FN+ Sbjct: 261 LVAVGRRPRTKGFNL 275 >3URH-A nrPDB Length = 491 Score = 38.3 bits (87), Expect = 0.017, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 +I+IGSG G A + GM V ++E R GG Sbjct: 26 YDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGG 62 >4USR-A nrPDB Length = 361 Score = 37.9 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 VI+IG G + L A L+ + LL+ + GG Sbjct: 6 PILDVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGG 44 >4K2X-A nrPDB Length = 523 Score = 37.9 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 272 PLPTKKTGK--VIIIGSGVSGLAAARQLQSFGMDVTLLE 308 +P + V+I G+G +GL A +L+ G +LE Sbjct: 14 LVPRGSHMRYDVVIAGAGPTGLMLACELRLAGARTLVLE 52 >5UWY-A nrPDB Length = 308 Score = 37.9 bits (86), Expect = 0.022, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV-ATFRKGNYVADLGAMVVTGL 337 +IIGSG +G+ AA + V ++E GG++ TF NY G ++G Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNLSVAIIEQGA-PGGQMNNTFDIENYP---GYDHISGP 60 Query: 338 G 338 Sbjct: 61 E 61 >1DEQ-A nrPDB Length = 390 Score = 37.9 bits (86), Expect = 0.022, Method: Composition-based stats. Identities = 31/119 (26%), Positives = 41/119 (34%), Gaps = 9/119 (7%) Query: 4 GKKAAAAAAAAAAAATGTEAGPGTAG-GSENGSEVAAQPAGLSGPAEVGPGAVGERTPRK 62 G + + A G+ PGT+ G+ N +G P PG+ G P + Sbjct: 252 GHARGDSVSQGTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGR 311 Query: 63 KEPPRASPPGGLAEPPGSAG--------PQAGPTVVPGSATPMETGIAETPEGRRTSRR 113 EP A PGSAG P + T PG P G T +S R Sbjct: 312 PEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFR 370 Score = 37.5 bits (85), Expect = 0.025, Method: Composition-based stats. Identities = 28/91 (30%), Positives = 36/91 (39%), Gaps = 4/91 (4%) Query: 25 PGTAGGSENGSEVAAQP----AGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGS 80 PG+ G +G+ +P AG P PG+ G P + EP A PGS Sbjct: 283 PGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGS 342 Query: 81 AGPQAGPTVVPGSATPMETGIAETPEGRRTS 111 AG PGSA TG + + R S Sbjct: 343 AGTWNPGRPEPGSAGTWNTGSSGSSSFRPDS 373 >2BRY-A nrPDB Length = 497 Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 19/31 (61%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 K +++G+G GL AA +L G V L+E R Sbjct: 94 KCLVVGAGPCGLRAAVELALLGARVVLVEKR 124 >4TXK-A nrPDB Length = 615 Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 19/31 (61%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 K +++G+G GL AA +L G V L+E R Sbjct: 86 KCLVVGAGPCGLRAAVELALLGARVVLVEKR 116 >4RG3-A nrPDB Length = 548 Score = 37.5 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 46/139 (33%), Gaps = 14/139 (10%) Query: 275 TKKTGKVIIIGSGVSGLAAARQL-QSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMV 333 T T ++IG+G G+ A +L G+ + D GG T+ Y GA+ Sbjct: 13 TTHTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGG---TWYWNRYP---GALS 66 Query: 334 VTGLGGNPMAVVSKQVNMELAKIK--QKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSY 391 T + + K + + E V + + + F E TS Sbjct: 67 DTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFD---LRRHFKFGTEVTSA 123 Query: 392 LSHQLDFNVLNNKPVSLGQ 410 L LD L G+ Sbjct: 124 L--YLDDENLWEVTTDHGE 140 >4N9X-A nrPDB Length = 411 Score = 37.5 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 3/47 (6%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLE---ARDRVGGRVATFR 321 + V+I G G+ GLA A LQ G+ + +LE A + G+ R Sbjct: 3 SFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQAAEPQTLGKGHALR 49 >6JDK-A nrPDB Length = 544 Score = 37.5 bits (85), Expect = 0.025, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 22/42 (52%), Gaps = 1/42 (2%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR 321 +I+G+G +G+ +L+ G V L EA +GG + + Sbjct: 19 DALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGG-IWYWN 59 >2YVG-A nrPDB Length = 408 Score = 37.5 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 30/53 (56%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVAD 328 + +++I+G GV GL A ++ G+ V+L+E + R+ R A ++VA Sbjct: 143 RPQSRLLIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAAPATLADFVAR 195 >5KOX-A nrPDB Length = 476 Score = 37.5 bits (85), Expect = 0.027, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 17/34 (50%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 VII G G +GL A +L+ G+ +LE Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTP 39 >3T14-A nrPDB Length = 437 Score = 37.1 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 24/39 (61%), Gaps = 3/39 (7%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSF---GMDVTLLEARD 311 + + V+I+G+G G+ AA +++ G +VTL+ A D Sbjct: 2 RGSAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISAND 40 >5J5Z-A nrPDB Length = 496 Score = 37.1 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 V +IGSG G AA + G +E + +GG Sbjct: 30 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG 65 >6ER9-A nrPDB Length = 549 Score = 36.7 bits (83), Expect = 0.048, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 1/50 (2%) Query: 280 KVIIIGSGVSGLAAARQLQS-FGMDVTLLEARDRVGGRVATFRKGNYVAD 328 ++IG+G G+ A +L + G+ V + D GG R ++D Sbjct: 11 DAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGGTWYWNRYPGALSD 60 >4B3J-A nrPDB Length = 736 Score = 36.3 bits (82), Expect = 0.050, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 36/98 (36%), Gaps = 8/98 (8%) Query: 262 INFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTL----LEARDRVGGRV 317 IN G R + + ++ ++G+G+ G A G +V L LEA + G+ Sbjct: 326 INAG-GSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAK--GKG 382 Query: 318 ATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAK 355 + + + G +A ++ + K Sbjct: 383 YSEKLEAKALERGRTT-QERSDALLARITPTADAADFK 419 >6N7F-A nrPDB Length = 453 Score = 36.3 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 I+IG G +G+A+A + G V L E ++ +GG Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAKVLLAEGKE-IGG 43 >6NWP-A nrPDB Length = 441 Score = 36.3 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 33/141 (23%), Positives = 56/141 (39%), Gaps = 14/141 (9%) Query: 32 ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAGPQAGP---T 88 E ++ + + L P E G G T K P A G+ G QA T Sbjct: 36 EGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT 95 Query: 89 VVPGSATPMETGIAETP--EGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAE 146 +P T E GI +TP E +A+ + + S+D S++++ A+ Sbjct: 96 EIPEGTTAEEAGIGDTPSLEDEAAGHVTQAR---------MVSKSKDGTGSDDKKAKGAD 146 Query: 147 KEKKLPPPPPQAPPEEENESE 167 + K+ P APP ++ ++ Sbjct: 147 GKTKIATPRGAAPPGQKGQAN 167 >5ZL9-A nrPDB Length = 618 Score = 36.3 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 37/122 (30%), Gaps = 10/122 (8%) Query: 733 GIFGSSAVPQPKETVVSRWRADPWA---RGSYSYVAAGSSGNDYDLMAQPITPGPSIPGA 789 G F + W+ D G + +A G ++ G G Sbjct: 373 GAFDLKNLGHQTALNAPAWKPDTAYTTVNGVNALLAQGVKPGK--IVVGTAMYGRGWTGV 430 Query: 790 PQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQS 849 + F G T V G +G+ + +IA QF+ + AT P Sbjct: 431 NGYQNNIPFTGTAT-----GPVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFK 485 Query: 850 PS 851 PS Sbjct: 486 PS 487 >4YKF-A nrPDB Length = 521 Score = 36.3 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 16/35 (45%), Positives = 19/35 (54%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 P K +V +IG G SG+ AA L VTLLE Sbjct: 351 PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 385 >1FL2-A nrPDB Length = 310 Score = 36.3 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 16/35 (45%), Positives = 19/35 (54%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 P K +V +IG G SG+ AA L VTLLE Sbjct: 140 PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 174 >4H7U-A nrPDB Length = 602 Score = 36.3 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 3/53 (5%) Query: 262 INFGIYKRIKP--LPTKKTGKVIIIGSGVSGLAAARQL-QSFGMDVTLLEARD 311 I G P LP+ I+ G G +GL A +L ++ V ++EA Sbjct: 22 IARGAITYQHPDDLPSGVDYDFIVAGGGTAGLVVASRLSENSNWKVLVIEAGP 74 >3ISH-A nrPDB Length = 311 Score = 36.3 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 21/48 (43%), Gaps = 1/48 (2%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV-ATFRKGNYV 326 IIG G +GL+A G+ +L + GG++ + NY Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYP 50 >1QO8-A nrPDB Length = 566 Score = 36.3 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 266 IYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 I K I P++ T +V+++G+G +G A+ + G +V L++ GG Sbjct: 110 IQKAIAAGPSETT-QVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSGG 158 >3LAD-A nrPDB Length = 476 Score = 36.3 bits (82), Expect = 0.058, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 23/51 (45%), Gaps = 3/51 (5%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLG 330 VI+IG+G G AA + G+ L+E + G+ G ++G Sbjct: 5 DVIVIGAGPGGYVAAIKSAQLGLKTALIE---KYKGKEGKTALGGTCLNVG 52 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 10/100 (10%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR----VGGRVAT-----FRKGNYVADL 329 GK+ +IG+GV GL G +VT+LEA D+ V +VA K L Sbjct: 181 GKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILL 240 Query: 330 GAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQA 369 GA VTG V K V+ E K + L A G+ Sbjct: 241 GA-RVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRR 279 >4MOP-A nrPDB Length = 633 Score = 36.3 bits (82), Expect = 0.061, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 39/118 (33%), Gaps = 19/118 (16%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG-RVATFRKGNYVADLGAMVVTGL 337 V+I+GSG G AR+L G V + + + G ++ +K + Sbjct: 47 YDVVIVGSGPIGCTYARELVGAGYKVAMFDIGEIDSGLKIGAHKKNTVEYQKNIDKFVNV 106 Query: 338 GGNPMAVVS-------------KQVNMELAKIK-----QKCPLYEANGQAVPKEKDEM 377 + VS ++ ++ PL +GQAV + M Sbjct: 107 IQGQLMSVSVPVNTLVVDTLSPTSWQASTFFVRNGSNPEQDPLRNLSGQAVTRVVGGM 164 >3II4-A nrPDB Length = 466 Score = 35.9 bits (81), Expect = 0.066, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 16/32 (50%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 V+++G+G G AA + G+ ++E Sbjct: 4 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVE 35 >6BWT-A nrPDB Length = 319 Score = 35.9 bits (81), Expect = 0.067, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 24/61 (39%), Gaps = 2/61 (3%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGL 337 K+II+GSG +G AA + ++ + GG++ T Y + G Sbjct: 7 HHKLIILGSGPAGYTAAIYAARANLKPVII-TGMQPGGQL-TTTTDVYNWPGEPDGIMGP 64 Query: 338 G 338 Sbjct: 65 E 65 >1Q1R-A nrPDB Length = 431 Score = 35.9 bits (81), Expect = 0.067, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 24/66 (36%), Gaps = 10/66 (15%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRV----------ATFRKGNYVA 327 ++++IG G GL A M VTLL+ RV RV R+ Sbjct: 149 DNRLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDI 208 Query: 328 DLGAMV 333 G V Sbjct: 209 RTGTQV 214 >5U63-A nrPDB Length = 321 Score = 35.9 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 27/71 (38%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTG 336 K K++I+GSG +G AA + L+ + G T N+ D +G Sbjct: 8 KHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTDEIENWPGDFEMTTGSG 67 Query: 337 LGGNPMAVVSK 347 L + K Sbjct: 68 LMQRMLQHAEK 78 >6IUM-B nrPDB Length = 701 Score = 35.9 bits (81), Expect = 0.077, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 PT+K KV +IG+G G + + G+ VT+LE + Sbjct: 288 PTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETK 324 >1C0L-A nrPDB Length = 363 Score = 35.9 bits (81), Expect = 0.077, Method: Composition-based stats. Identities = 15/32 (46%), Positives = 22/32 (68%), Gaps = 1/32 (3%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARD 311 +V+++GSGV GL++A L G V +L ARD Sbjct: 8 RVVVLGSGVIGLSSALILARKGYSVHIL-ARD 38 >5ER0-A nrPDB Length = 518 Score = 35.9 bits (81), Expect = 0.080, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 K+ ++ +IG+G G A + G DVTL++A RV Sbjct: 194 AKEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARV 232 >6C6P-A nrPDB Length = 458 Score = 35.9 bits (81), Expect = 0.082, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 ++ +VII+G+GV G A A L G VT++E Sbjct: 4 SQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE 37 >6BZ0-A nrPDB Length = 480 Score = 35.6 bits (80), Expect = 0.087, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVG 314 +++IG G G AA + G V +E R G Sbjct: 9 DLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNG 43 >2UZZ-A nrPDB Length = 372 Score = 35.6 bits (80), Expect = 0.090, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 9/92 (9%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEAR---DRVGGRVATFRKGNYVADLGAMVVT 335 +IIIGSG G AA G++V + +A + G R + G V Sbjct: 3 YDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYV- 61 Query: 336 GLGGNPMAVVSKQVNMELAKIKQKCPLYEANG 367 P+ + ++ + EL++ + P++ +G Sbjct: 62 -----PLVLRAQMLWDELSRHNEDDPIFVRSG 88 >5Z7M-A nrPDB Length = 546 Score = 35.6 bits (80), Expect = 0.096, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 24/70 (34%), Gaps = 5/70 (7%) Query: 782 PGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQAT 841 G G + F G T V G +G+ + +IA QF+ + AT Sbjct: 421 YGRGWTGVNGYQNNIPFTGTAT-----GPVKGTWENGIVDYRQIAGQFMSGEWQYTYDAT 475 Query: 842 PGVPAQQSPS 851 P PS Sbjct: 476 AEAPYVFKPS 485 >2WTB-A nrPDB Length = 725 Score = 35.6 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 23/61 (37%), Gaps = 1/61 (1%) Query: 252 VHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARD 311 +H + + G +P K KV IIG G+ G A L V L E + Sbjct: 287 IHVFFSQRGTAKVPGVTDRGLVPRK-IKKVAIIGGGLMGSGIATALILSNYPVILKEVNE 345 Query: 312 R 312 + Sbjct: 346 K 346 >6A37-A nrPDB Length = 552 Score = 35.6 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 27/178 (15%), Positives = 59/178 (33%), Gaps = 39/178 (21%) Query: 265 GIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQ-SFGMDVTLLEARDRVGGRVATFRKG 323 G+ R + K IIIG+G GL + ++L+ F + V + VGG + Sbjct: 13 GLVPRGSHMTQKMDFDAIIIGAGFGGLYSLKKLRDDFNLKVRAFDRATEVGG-TWFWN-- 69 Query: 324 NYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFN 383 L + + + EL + + +++++ Sbjct: 70 --------QYPGALSDSETHLYCYSWDKELLQEME-------------------IKRKYI 102 Query: 384 RLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEEL 441 + +YL D + L + ++ ++ + DE+ W + E+ Sbjct: 103 SQPDVLAYLKRVADKHDLR-------KDIQFETGIRSAYF-DEENSFWNVTTENDEKF 152 >3COX-A nrPDB Length = 507 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 26/68 (38%), Gaps = 12/68 (17%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVA-TFRKGNYVA------DLGAMVV 334 ++IGSG G AA +L G+ ++E GR T + D +M + Sbjct: 15 LVIGSGYGGAVAALRLTQAGIPTQIVEM-----GRSWDTPGSDGKIFCGMLNPDKRSMWL 69 Query: 335 TGLGGNPM 342 P+ Sbjct: 70 ADKTDQPV 77 >5USX-A nrPDB Length = 319 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTG 336 K K++I+GSG +G AA ++ L+ + G T N+ D +TG Sbjct: 5 KHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQGGQLTTTTEVENWPGD--PEGLTG 62 Query: 337 LG 338 G Sbjct: 63 PG 64 >2VHY-A nrPDB Length = 377 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 8/64 (12%) Query: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEAR-DRVG-------GRVATFRKGN 324 +P + V++IG+G +G AAR G VT+L+ D++ GR+ T Sbjct: 163 VPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSA 222 Query: 325 YVAD 328 Y + Sbjct: 223 YELE 226 >6BPY-A nrPDB Length = 374 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 23/62 (37%), Gaps = 8/62 (12%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFGMDVTLLEA----RDRVGGRVATF----RKGNYVADL 329 KV+IIGSG + AA L + L E GG++ T + + Sbjct: 4 HTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFPDGI 63 Query: 330 GA 331 G Sbjct: 64 GG 65 >5XGV-A nrPDB Length = 462 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 17/33 (51%) Query: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 VII G G GL A +L G+D +LE D Sbjct: 4 VIIAGGGPVGLMLACELGLAGVDTVVLERHDAP 36 >5U8W-A nrPDB Length = 481 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 32/88 (36%), Gaps = 15/88 (17%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 339 V++IG+G G AA + G+ +E Y+ G + + G Sbjct: 9 DVVVIGAGPGGYVAAIRAAQLGLKTACIE---------------KYIGKEGKVALGGTCL 53 Query: 340 NPMAVVSKQVNMELAKIKQKCPLYEANG 367 N + SK + K + ++ +G Sbjct: 54 NVGCIPSKALLDSSYKYHEAKEAFKVHG 81 Score = 32.5 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 20/33 (60%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 312 K+ +IG+GV GL G +VT+LEA D+ Sbjct: 186 KLGVIGAGVIGLELGSVWARLGAEVTVLEALDK 218 >3NIX-A nrPDB Length = 421 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 17/30 (56%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEA 309 V++IG+G +G AA + G V ++E Sbjct: 7 DVLVIGAGPAGTVAASLVNKSGFKVKIVEK 36 >5TR3-A nrPDB Length = 481 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 19/39 (48%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVA 318 V++IG+G G AA + G+ +E G++A Sbjct: 9 DVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLA 47 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARD 311 ++ +IG+GV GL G +VT+LEA D Sbjct: 186 RLGVIGAGVIGLELGSVWARLGAEVTVLEALD 217 >3G5Q-A nrPDB Length = 443 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 312 +V ++G+G++G AA L G+ V L E R + Sbjct: 3 RVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPK 35 >3RQ4-A nrPDB Length = 247 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 9/71 (12%) Query: 83 PQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKV------EYREMDESLANLSEDEY- 135 P++G T++P + MET A+ R + ++ ++ E RE DE L E+++ Sbjct: 101 PESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLELLVGCIAELREADEGLLRAGENDFS 160 Query: 136 --YSEEERNAK 144 YS +R+A+ Sbjct: 161 IMYSTRKRSAQ 171 >1GPE-A nrPDB Length = 587 Score = 34.8 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFG-MDVTLLEA 309 KT II G G++GL A +L + V ++E Sbjct: 23 KTYDYIIAGGGLTGLTVAAKLTENPKIKVLVIEK 56 >5J7X-A nrPDB Length = 549 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 278 TGKVIIIGSGVSGLAAARQLQS-FGMDVTLLEARDRVGGRVATFRKGNYV 326 +IIGSG SG+ +L+ + V + EA +GG T+ Y Sbjct: 12 HLDALIIGSGFSGIYLLHKLRDELKLKVKIFEAESDIGG---TWNNNRYP 58 >3L8K-A nrPDB Length = 466 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 264 FGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 FG + LP ++IIG+G GL A + G+ ++E DR Sbjct: 162 FGYKTSFRKLPQD----MVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRA 207 >4JNQ-A nrPDB Length = 345 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 32/82 (39%), Gaps = 3/82 (3%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 T++ VI+IGSG +G AA + ++ + G + T NY V Sbjct: 23 TQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEP--V 80 Query: 335 TGL-GGNPMAVVSKQVNMELAK 355 G MA ++ V ++ Sbjct: 81 QGPWMMEQMARQAENVGAQIVH 102 >3SM8-A nrPDB Length = 381 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 5/50 (10%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVG----GRVATFRKGNY 325 ++IG+G++G + L + G V +LE + G GR A Y Sbjct: 11 DYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAY 59 >6AON-A nrPDB Length = 478 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 18/33 (54%) Query: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEA 309 K V++IG+G G AA + GM V ++A Sbjct: 6 KQFDVVVIGAGPGGYIAAIRAAQLGMSVACIDA 38 >4AU7-A nrPDB Length = 247 Score = 34.4 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 9/71 (12%) Query: 83 PQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKV------EYREMDESLANLSEDEY- 135 P++G T++P + MET A+ R + ++ ++ E RE DE L E+++ Sbjct: 103 PESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLELLVGCIAELREEDEDLLRAGENDFS 162 Query: 136 --YSEEERNAK 144 YS +R+A+ Sbjct: 163 IMYSTRKRSAQ 173 >4Z25-A nrPDB Length = 652 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 278 TGKVIIIGSGVSGLAAARQLQSFG-MDVTLLEARD 311 TG ++IIG+G +G A L F M + LLEA Sbjct: 6 TGDIVIIGAGAAGSLLAHYLARFSNMKIILLEAGH 40 >1FOH-A nrPDB Length = 664 Score = 34.0 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 21/36 (58%), Gaps = 5/36 (13%) Query: 280 KVIIIGSGVSGLAAARQLQSF-----GMDVTLLEAR 310 V+I+G+G +GL AAR L + + V +++ R Sbjct: 9 DVLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKR 44 >1EBD-A nrPDB Length = 455 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 282 IIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 +++G+G G AA + G VT++E + +GG Sbjct: 7 LVVGAGPGGYVAAIRAAQLGQKVTIVEKGN-LGG 39 >1UKV-G nrPDB Length = 453 Score = 34.0 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATF 320 VI++G+G++ + L G V ++ +D GG A+ Sbjct: 9 DTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASV 53 >1GAL-A nrPDB Length = 583 Score = 34.0 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 17/71 (23%) Query: 265 GIYKRIKPLPTKKTGKVI---IIGSGVSGLAAARQLQSFG-MDVTLLEARDRVGGRVATF 320 GI + P +G+ + I G G++GL A +L + V ++E+ Sbjct: 3 GIEASLLTDPKDVSGRTVDYIIAGGGLTGLTTAARLTENPNISVLVIES----------- 51 Query: 321 RKGNYVADLGA 331 G+Y +D G Sbjct: 52 --GSYESDRGP 60 >5JCN-A nrPDB Length = 451 Score = 33.6 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK----GNYVADLG 330 KK GK +I+G G GL + L+ DVT++ R+ T +Y + G Sbjct: 177 AKKGGKAVIVGGGYIGLELSAALKINDFDVTMVFPEPWCMPRLFTADIAAFYESYYTNKG 236 Query: 331 AMVVTGL 337 +V G Sbjct: 237 VKIVKGT 243 >2CUL-A nrPDB Length = 232 Score = 33.6 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 +V+I+G+G SG A L G+ V LL Sbjct: 4 YQVLIVGAGFSGAETAFWLAQKGVRVGLLTQS 35 >5EVY-X nrPDB Length = 438 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 19/41 (46%), Gaps = 1/41 (2%) Query: 275 TKKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVG 314 +K +V +IG G++G A A L +V L E G Sbjct: 19 SKSPLRVAVIGGGIAGTALALGLSKSSHVNVKLFETAPAFG 59 >5MQ0-T nrPDB Length = 877 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 5/85 (5%) Query: 425 DEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFL----- 479 IE+WK+ +T ++++ L + + + + Y K + + F Sbjct: 41 KRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRWESTKEVVETSRIFWLFQRC 100 Query: 480 VKSKHRDLTALCKEYDELAETQGKL 504 +KS RD +C Y ELA Q L Sbjct: 101 LKSCVRDCDRICLSYLELAIEQYDL 125 >4NTC-A nrPDB Length = 335 Score = 33.6 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEA 309 V+IIG+G +GL+ A L + ++ Sbjct: 16 DVLIIGAGPAGLSTATGLARQLHTAVVFDS 45 >4CPD-A nrPDB Length = 347 Score = 33.6 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 8/78 (10%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVT 335 + V +IG+G GL A Q G L A DR+ R+ A LGA+ + Sbjct: 167 RPGDSVAVIGAGPVGLMAIEVAQVLGASKIL--AIDRIPERLERA------ASLGAIPIN 218 Query: 336 GLGGNPMAVVSKQVNMEL 353 NP+ V + N E Sbjct: 219 AEQENPVRRVRSETNDEG 236 >1KOB-A nrPDB Length = 387 Score = 33.2 bits (74), Expect = 0.43, Method: Composition-based stats. Identities = 26/168 (15%), Positives = 56/168 (33%), Gaps = 19/168 (11%) Query: 645 EWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILL 704 K S+V+ + FG K+ + R + + +++ +L Sbjct: 184 TKKASSVKIIDFGLATKLN---PDEIVKVTTATAEFAAPEIVDREPVGFYTDMWAIGVLG 240 Query: 705 ALVAG-----EAAGIMENI---------SDDVIVGRCLAILKGIFGSSAVPQPKETV-VS 749 ++ +E + D+ K + +P++ + V Sbjct: 241 YVLLSGLSPFAGEDDLETLQNVKRCDWEFDEDAFSSVSPEAKDFIKNLLQKEPRKRLTVH 300 Query: 750 RWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQP-IPRL 796 PW +G +S + + + Y+ + Q I + APQP I R+ Sbjct: 301 DALEHPWLKGDHSNLTSRIPSSRYNKIRQKIKEKYADWPAPQPAIGRI 348 >5X6R-A nrPDB Length = 420 Score = 33.2 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRK 322 V IIG+G+ G AA G +VTL + R R+ T + Sbjct: 30 SVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDP--RLDTTKN 70 >5Z6Q-A nrPDB Length = 392 Score = 33.2 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 25/108 (23%) Query: 51 GPGAVGERTPRKKEP----PRASPPGGLAEPPGSAG--------PQAGPTVVPG---SAT 95 GPG+ G P++K+P + P GSAG +G ++V G + Sbjct: 1 GPGSSGA-VPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPSYSGLSMVSGVKQGSG 59 Query: 96 PMETGIAETPEGRRT---------SRRKRAKVEYREMDESLANLSEDE 134 P T TP+ RT +R+K+ +R +D +LANL +E Sbjct: 60 PAPTTHKGTPKTNRTNKPSTPTTATRKKKDLKNFRNVDSNLANLIMNE 107 >3IP1-A nrPDB Length = 404 Score = 33.2 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 25/68 (36%), Gaps = 10/68 (14%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVV 334 + V+I+G G GLAA L+ G V L E + + N +LGA V Sbjct: 212 RPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEV---------RRNLAKELGADHV 262 Query: 335 TGLGGNPM 342 Sbjct: 263 IDPTKENF 270 >4Z44-A nrPDB Length = 554 Score = 33.2 bits (74), Expect = 0.52, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 276 KKTGKVIIIGSGVSGLAAARQLQSF---GMDVTLLE--ARDRVG 314 K ++I+G G +G AA L ++TL+E A R+G Sbjct: 19 KPIKNIVIVGGGTAGWMAASYLVRALQQQANITLIESAAIPRIG 62 >3NTA-A nrPDB Length = 574 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 9/57 (15%) Query: 283 IIGSGVSGLAAARQLQSFGMDVTLLEARDRV---------GGRVATFRKGNYVADLG 330 ++G G GL L G+ TLLE D+V G R LG Sbjct: 156 VVGGGFIGLEMMESLHHLGIKTTLLELADQVMTPVDREMAGFAHQAIRDQGVDLRLG 212 >2EEZ-A nrPDB Length = 369 Score = 32.9 bits (73), Expect = 0.71, Method: Composition-based stats. Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 8/54 (14%) Query: 274 PTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEAR--------DRVGGRVAT 319 P V+I+G G G AA+ G VT+L+ D GGRV T Sbjct: 162 PGVAPASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVIT 215 >5X68-A nrPDB Length = 391 Score = 32.5 bits (72), Expect = 0.72, Method: Composition-based stats. Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGN 324 KV +IG G+ G A L + + EAR+ RVATF +G Sbjct: 16 KVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDT--RVATFTRGR 58 >3D8X-A nrPDB Length = 326 Score = 32.5 bits (72), Expect = 0.73, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 14/30 (46%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLE 308 KV IIGSG + AA L + L E Sbjct: 11 NKVTIIGSGPAAHTAAIYLARAEIKPILYE 40 >1OQY-A nrPDB Length = 368 Score = 29.8 bits (65), Expect = 5.9, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 25/54 (46%) Query: 17 AATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASP 70 A GT A P + + S + PA SG + P A +++P ++ P SP Sbjct: 86 AGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSP 139 >2QA1-A nrPDB Length = 500 Score = 29.8 bits (65), Expect = 6.0, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 15/21 (71%) Query: 281 VIIIGSGVSGLAAARQLQSFG 301 VI++G+G +G+ A +L+ G Sbjct: 14 VIVVGAGPAGMMLAGELRLAG 34 >3OZ2-A nrPDB Length = 397 Score = 29.4 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 25/72 (34%), Gaps = 4/72 (5%) Query: 292 AAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNM 351 AAR +G+ ++E R +G V G + + + + ++ Sbjct: 18 TAARYAAKYGLKTLMIEKRPEIGSPVRC----GEGLSKGILNEADIKADRSFIANEVKGA 73 Query: 352 ELAKIKQKCPLY 363 + +K P+ Sbjct: 74 RIYGPSEKRPII 85 >1DXL-A nrPDB Length = 470 Score = 29.0 bits (63), Expect = 9.6, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 18/37 (48%) Query: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 V+IIG G G AA + G T +E R +GG Sbjct: 7 NDVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGG 43 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.303 0.122 0.322 Lambda K H 0.267 0.0369 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,743,904 Number of Sequences: 36641 Number of extensions: 1226132 Number of successful extensions: 7025 Number of sequences better than 10.0: 308 Number of HSP's better than 10.0 without gapping: 336 Number of HSP's successfully gapped in prelim test: 180 Number of HSP's that attempted gapping in prelim test: 4888 Number of HSP's gapped (non-prelim): 1372 length of query: 852 length of database: 10,336,785 effective HSP length: 105 effective length of query: 747 effective length of database: 6,489,480 effective search space: 4847641560 effective search space used: 4847641560 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 63 (29.0 bits)