BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O60218 (316 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ZUA-X nrPDB 654 0.0 1C9W-A nrPDB 534 e-152 1FRB-A nrPDB 525 e-149 3O3R-A nrPDB 501 e-142 3RX4-A nrPDB 458 e-129 1DLA-A nrPDB 447 e-126 3G1R-A nrPDB 331 2e-91 4GAC-A nrPDB 326 9e-90 2ALR-A nrPDB 319 1e-87 1Q5M-A nrPDB 318 2e-87 1HQT-A nrPDB 318 2e-87 4HBK-A nrPDB 314 3e-86 4JQA-A nrPDB 310 4e-85 2FVL-A nrPDB 310 4e-85 5JM5-A nrPDB 303 6e-83 5UXF-A nrPDB 294 4e-80 1AFS-A nrPDB 290 7e-79 2HE8-A nrPDB 278 2e-75 3H7U-A nrPDB 239 1e-63 5JH1-A nrPDB 232 1e-61 3KRB-A nrPDB 231 4e-61 3WCZ-A nrPDB 224 3e-59 3H7R-A nrPDB 221 4e-58 4F40-A nrPDB 219 9e-58 1VBJ-A nrPDB 215 2e-56 4GIE-A nrPDB 214 5e-56 5ZCM-A nrPDB 208 2e-54 1QWK-A nrPDB 206 8e-54 1K8C-A nrPDB 202 1e-52 5Z6T-A nrPDB 202 2e-52 2BGQ-A nrPDB 197 3e-51 1MZR-A nrPDB 193 6e-50 4IJC-A nrPDB 192 2e-49 3D3F-A nrPDB 189 2e-48 1VP5-A nrPDB 182 1e-46 3UP8-A nrPDB 168 2e-42 4MHB-A nrPDB 157 6e-39 4OTK-A nrPDB 155 2e-38 1A80-A nrPDB 153 1e-37 4H8N-A nrPDB 143 9e-35 3WG6-A nrPDB 116 1e-26 1PYF-A nrPDB 70 2e-12 1PZ1-A nrPDB 69 4e-12 1LQA-A nrPDB 50 9e-07 4R9O-A nrPDB 49 2e-06 3N6Q-A nrPDB 45 3e-05 1OG6-A nrPDB 43 2e-04 1GVE-A nrPDB 36 0.019 5BVC-A nrPDB 31 0.56 4EHI-A nrPDB 31 0.68 4KM3-A nrPDB 31 0.72 3KRZ-A nrPDB 30 1.4 5Y0V-A nrPDB 29 2.1 2BP1-A nrPDB 28 4.4 6EOJ-D nrPDB 28 4.9 2Z1K-A nrPDB 28 5.1 4QNY-A nrPDB 28 7.4 3ZHS-A nrPDB 27 9.3 >1ZUA-X nrPDB Length = 317 Score = 654 bits (1688), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/316 (100%), Positives = 316/316 (100%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ Sbjct: 2 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 61 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD Sbjct: 62 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 121 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP Sbjct: 122 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 181 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK Sbjct: 182 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 241 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN Sbjct: 242 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 301 Query: 301 VLQSSHLEDYPFNAEY 316 VLQSSHLEDYPFNAEY Sbjct: 302 VLQSSHLEDYPFNAEY 317 >1C9W-A nrPDB Length = 315 Score = 534 bits (1376), Expect = e-152, Method: Compositional matrix adjust. Identities = 262/315 (83%), Positives = 294/315 (93%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 +TFVELSTKAKMPIVGLGTW+SP G+VKEAVKVAIDAGYRHIDCAY Y NEHEVGEAIQE Sbjct: 1 STFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQE 60 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI+EKAV+REDLFIVSKLWPT FER L+++AF+KTL DLKL YLD+YLIHWPQG + G + Sbjct: 61 KIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 LFPKDD+GN + K TFLDAWE MEELVDEGLVKALGVSNF+HFQIE++LNKPGLK+KPV Sbjct: 121 LFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPV 180 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 TNQVECHPYLTQEKLI+YCHSKGITVTAYSPLGSP+RPWAKPEDPSLLEDPKIKEIAAKH Sbjct: 181 TNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301 KKT+AQVLIRFHIQRNV+VIPKSVTPARI EN QVFDF+LSD+EMATIL FNRNWRAC + Sbjct: 241 KKTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACLL 300 Query: 302 LQSSHLEDYPFNAEY 316 ++ ++E+YP++AEY Sbjct: 301 PETVNMEEYPYDAEY 315 >1FRB-A nrPDB Length = 315 Score = 525 bits (1351), Expect = e-149, Method: Compositional matrix adjust. Identities = 259/315 (82%), Positives = 292/315 (92%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 ATFVELSTKAKMPIVGLGTWKSP +VKEAVK AIDAGYRHIDCAY Y NE+EVGEAIQE Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI+EKAV+REDLFIVSKLWPT FE+ L+++AF+KTL DLKL YLD+YLIHWPQG + G + Sbjct: 61 KIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 LFPKDD+G + K TFL+AWE MEELVD+GLVKALGVSNF+HFQIE+LLNKPGLK+KPV Sbjct: 121 LFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 180 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 TNQVECHPYLTQEKLIQYCHSKGI+VTAYSPLGSPDRP AKPEDPSLLEDPKIKEIAAKH Sbjct: 181 TNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301 +KT+AQVLIRFHIQRNV+VIPKSVTP+RI ENIQVFDF+LSDEEMATILSFNRNWRAC + Sbjct: 241 EKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLL 300 Query: 302 LQSSHLEDYPFNAEY 316 ++ ++E+YP++AEY Sbjct: 301 PETVNMEEYPYDAEY 315 >3O3R-A nrPDB Length = 316 Score = 501 bits (1289), Expect = e-142, Method: Compositional matrix adjust. Identities = 247/316 (78%), Positives = 279/316 (88%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 M TFV+L TKAKMP+VGLGTWKSP G+VKEAVK AIDAGYRH DCAYVYQNE EVGEAIQ Sbjct: 1 MTTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQ 60 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EKI+EKAV+REDLFIVSKLW TFFE+ L+++AF+KTL DLKL YLD+YLIHWPQG ++G Sbjct: 61 EKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGK 120 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + PKD +G + K+TFLDAWE MEELVD+GLVKALGVSNF+HFQIE+LLNKPGLK+KP Sbjct: 121 EFLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKP 180 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 VTNQVECHPYLTQEKLIQYCHSKGI V AYSPLGSPDRP+AKPEDP +LE PKIKEIAAK Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAK 240 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HKKT AQVLIRFH+QRNV VIPKSVT + I ENIQVFDF+LS+E+MA ILS NRNWRAC Sbjct: 241 HKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACG 300 Query: 301 VLQSSHLEDYPFNAEY 316 + +S ED+PF+ EY Sbjct: 301 LFVTSDEEDFPFHEEY 316 >3RX4-A nrPDB Length = 336 Score = 458 bits (1178), Expect = e-129, Method: Compositional matrix adjust. Identities = 223/316 (70%), Positives = 263/316 (83%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 MA+ + L+ AKMPI+GLGTWKSP G+V EAVKVAID GYRHIDCA+VYQNE+EVG AIQ Sbjct: 21 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 80 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EK++E+ VKRE+LFIVSKLW T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G Sbjct: 81 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 140 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FP D+ GN + LD W AMEELVDEGLVKA+G+SNF+H Q+E +LNKPGLKYKP Sbjct: 141 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 200 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK Sbjct: 201 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 260 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 H KT AQVLIRF +QRN++VIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C Sbjct: 261 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 320 Query: 301 VLQSSHLEDYPFNAEY 316 +L + +DYPF+ E+ Sbjct: 321 LLSCTSHKDYPFHEEF 336 >1DLA-A nrPDB Length = 314 Score = 447 bits (1149), Expect = e-126, Method: Compositional matrix adjust. Identities = 224/310 (72%), Positives = 259/310 (83%) Query: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66 L T AKMPI+GLGTWKSP GKV EAVKVAID GYRHIDCA+VYQNE+EVG +QEK+Q + Sbjct: 5 LYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQ 64 Query: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126 VKREDLFIVSKLW T E+ LV+ A + TL+DLKL YLD+YLIHWP GFK G D FP D Sbjct: 65 VVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLD 124 Query: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186 GN + ++ F++ WEAMEELVDEGLVKA+GVSNF+H Q+EK+LNKPGLKYKP NQ+E Sbjct: 125 GDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIE 184 Query: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAA 246 HPYLTQEKLI+YC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK+ KT A Sbjct: 185 VHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTA 244 Query: 247 QVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSH 306 QVLIRF +QRN+IVIPKSVTP RI EN QVFDF+LS E+M T+LS+NRNWR C ++ + Sbjct: 245 QVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMSCAS 304 Query: 307 LEDYPFNAEY 316 +DYPF+ EY Sbjct: 305 HKDYPFHEEY 314 >3G1R-A nrPDB Length = 346 Score = 331 bits (849), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 161/317 (50%), Positives = 214/317 (67%), Gaps = 5/317 (1%) Query: 5 VELSTKAKMPIVGLGTWK----SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 + LS +PI+GLGT+ +P G +VKVAID GYRHID AY+YQNEHEVGEAI+ Sbjct: 30 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 89 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EKI E V+RED+F KLW T +VR E+TL+ L+L Y+D+Y+I P FK GD Sbjct: 90 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 149 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 +++P+D+ G + K+ WEAME D GLVK+LGVSNF+ Q+E +LNKPGLK+KP Sbjct: 150 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 209 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP-WAKPEDPSLLEDPKIKEIAA 239 V+NQVECHPY TQ KL+++C I +TAYSPLG+ P W P LL+D + + Sbjct: 210 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 269 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 ++ KTAAQ+++RF+IQR V+VIPKS RI EN Q+FDF L++EEM I + N+N R Sbjct: 270 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 329 Query: 300 NVLQSSHLEDYPFNAEY 316 +L +YPF+ EY Sbjct: 330 ELLMWRDHPEYPFHDEY 346 >4GAC-A nrPDB Length = 324 Score = 326 bits (835), Expect = 9e-90, Method: Compositional matrix adjust. Identities = 163/325 (50%), Positives = 218/325 (67%), Gaps = 12/325 (3%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A+ V L T KMP++GLGTWKS G+VK A+K A+ AGYRHIDCA VY NE E+GEA++E Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 62 KIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 + KAV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FPK+ G + + W+A+E LV +GLVKALG+SNF+ QI+ +L+ ++ P Sbjct: 122 NPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR--P 179 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 QVECHPYL Q +LI +CH++G+ VTAYSPLGS DR W P++P LLE+P + +A K Sbjct: 180 AVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEK 239 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR--- 297 H ++ AQ+L+R+ +QR VI IPKS+ P+RI++NIQVFDF S EEM + + N+NWR Sbjct: 240 HGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIV 299 Query: 298 ------ACNVLQSSHLEDYPFNAEY 316 V + + YPFN Y Sbjct: 300 PMITVDGKRVPRDAGHPLYPFNDPY 324 >2ALR-A nrPDB Length = 324 Score = 319 bits (817), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 159/325 (48%), Positives = 217/325 (66%), Gaps = 12/325 (3%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A+ V L T KMP++GLGTWKS G+VK AVK A+ GYRHIDCA +Y NE E+GEA++E Sbjct: 2 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 61 Query: 62 KIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 + KAV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD Sbjct: 62 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FPK+ G + + W+A+E LV +GLV+ALG+SNF+ QI+ +L+ ++ P Sbjct: 122 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 179 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P++P LLE+P + +A K Sbjct: 180 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 239 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR--- 297 + ++ AQ+L+R+ +QR VI IPKS+TP+RI++NI+VFDF S EEM + + N+NWR Sbjct: 240 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 299 Query: 298 ------ACNVLQSSHLEDYPFNAEY 316 V + + YPFN Y Sbjct: 300 PMLTVDGKRVPRDAGHPLYPFNDPY 324 >1Q5M-A nrPDB Length = 322 Score = 318 bits (816), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 160/316 (50%), Positives = 209/316 (66%), Gaps = 4/316 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V LS +P++G GT+ + P K EA K+AIDAG+RHID AY Y+NE EVG AI+ Sbjct: 7 VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRS 66 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI + VKRED+F SKLW TF LVR + E +LK+L+L Y+D+Y+IH+P K G + Sbjct: 67 KIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVE 126 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 + P D+ G AI WEAME+ D GL K++GVSNF+ Q+E +LNKPGLKYKPV Sbjct: 127 IIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 186 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP-WAKPEDPSLLEDPKIKEIAAK 240 NQVECHPYL Q KL+++C SKGI + AYS LGS P W P LLEDP I +A K Sbjct: 187 CNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKK 246 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 H++T A + +R+ +QR ++V+ KS T RI ENIQVF+F+L E+M I S NRN+R Sbjct: 247 HQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYVT 306 Query: 301 VLQSSHLEDYPFNAEY 316 + +YPF+ EY Sbjct: 307 ADFAIGHPNYPFSDEY 322 >1HQT-A nrPDB Length = 326 Score = 318 bits (814), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 161/325 (49%), Positives = 215/325 (66%), Gaps = 12/325 (3%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A+ V L T KMP++GLGTWKS G+VK A+K A+ GYRHIDCA ++ NE E+GEA+QE Sbjct: 4 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQE 63 Query: 62 KIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 + KAV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD Sbjct: 64 TVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 123 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FPK+ G + D W+A+E LV +GLV+ALG+SNFS QI+ +L+ ++ P Sbjct: 124 NPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVR--P 181 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P +P LLE+P ++ +A K Sbjct: 182 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEK 241 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR--- 297 + ++ AQ+L+R+ +QR VI IPKSVTP+RI +NIQVFDF S EEM + + N+N R Sbjct: 242 YNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLRFIV 301 Query: 298 ------ACNVLQSSHLEDYPFNAEY 316 V + + YPFN Y Sbjct: 302 PMLTVDGKRVPRDAGHPLYPFNDPY 326 >4HBK-A nrPDB Length = 344 Score = 314 bits (804), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 158/312 (50%), Positives = 211/312 (67%), Gaps = 5/312 (1%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++++ +P++GLGTW SP G+V AVK A++ GYRH+DCAYVY+NE E+GEA++ + Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124 +KRED+FI SKLW TFF VRKA E+TLK+L+L+YLD+YLIHWP K G DLFP Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184 D G D W+ ME+LVDEGLVK++G+SNF+ QI+ +L + KP Q Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEH--CRIKPANLQ 215 Query: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244 +E H KL++Y S G+TVTAY+PLGSP P +LL P + EIA +HKKT Sbjct: 216 IEIHANFPNIKLVEYAQSVGLTVTAYAPLGSPAH---SPGKVNLLTKPCVLEIAHRHKKT 272 Query: 245 AAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQS 304 AQVL+R+ +QR +IV+PKSVT RI EN QVFDF+LS+EEM + + + N R +LQ Sbjct: 273 PAQVLLRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELNTESLNERQFTLLQM 332 Query: 305 SHLEDYPFNAEY 316 S ++YPF EY Sbjct: 333 SGHQEYPFKEEY 344 >4JQA-A nrPDB Length = 331 Score = 310 bits (795), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 154/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V+L+ MP++G GT+ + P K EAVK+AI+AG+ HID A+VY NE +VG AI+ Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI + +VKRED+F SKLW LVR A E++LK+L+L Y+D+YLIH+P K G++ Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 + PKD+ G + WEAME+ D GL K++GVSNF+H +E +LNKPGLKYKPV Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240 NQVECHPY Q KL+ +C SK I + AYS LGS + PW P P LLEDP + +A K Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HK+T A + +R+ +QR V+V+ KS RI +N+QVF+F+L+ EEM I NRN R Sbjct: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307 Query: 301 VLQSSHLEDYPFNAEY 316 + + +YPF+ EY Sbjct: 308 LDIFAGPPNYPFSDEY 323 >2FVL-A nrPDB Length = 324 Score = 310 bits (795), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 152/316 (48%), Positives = 208/316 (65%), Gaps = 4/316 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 VEL+ MP++G GT+ + P + E K+AI+AG+RHID AY+Y NE +VG AI+ Sbjct: 9 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 68 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI + +VKRED+F SKLW TFF+ +V+ A E +LK L+L Y+D+YL+H+P K G+ Sbjct: 69 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 128 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 PKD+ G I WE ME+ D GL K++GVSNF++ Q+E +LNKPGLKYKPV Sbjct: 129 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPV 188 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240 NQVECHPYL Q KL+ +C SK I + A+S LG+ + W P P LLEDP + +A K Sbjct: 189 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKK 248 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HK+T A + +R+ +QR V+V+ KS RI ENIQVF+F+L+ E+M + NRN+R Sbjct: 249 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVV 308 Query: 301 VLQSSHLEDYPFNAEY 316 + DYPF+ EY Sbjct: 309 MDFLMDHPDYPFSDEY 324 >5JM5-A nrPDB Length = 332 Score = 303 bits (776), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 150/316 (47%), Positives = 204/316 (64%), Gaps = 4/316 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V+L+ MP++G GT+ + P K E K+AI+AG+RHID A++Y NE +VG AI+ Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI + +VKRED+F SKLW TF LVR A E +LK +L Y+D+YLIH P K G++ Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 L P D+ G I WEAME+ D GL K++GVSNF+ Q+E +LNKPGLKYKPV Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240 NQVECHPY + KL+ +C SK I + AYS LGS D+ W P P LLEDP + +A K Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKK 247 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HK+T A + +R+ +QR V+V+ KS RI +N+QVF+F+L+ E+M I +RN N Sbjct: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFN 307 Query: 301 VLQSSHLEDYPFNAEY 316 + +YP++ EY Sbjct: 308 SDSFASHPNYPYSDEY 323 >5UXF-A nrPDB Length = 342 Score = 294 bits (752), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 149/319 (46%), Positives = 207/319 (64%), Gaps = 10/319 (3%) Query: 5 VELSTKAKMPIVGLGTWKS---PLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V+L+ +P +G GT+K P K EA +A+D GYRH+D AY YQ E E+G+AIQ Sbjct: 27 VKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQS 86 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 I VKREDLF+ +KLW T F LV+ A EK+LK L+L Y+D+Y++H+P KSGD+ Sbjct: 87 AIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDN 146 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 FP +++G ++ F D WE +EE D GLVK++GVSNF+H Q+E++LNKPGLKYKPV Sbjct: 147 DFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPV 206 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD-RPWAKPEDPSLLEDPKIKEIAAK 240 NQVECH YL Q KL+ YC SK I + AY LG+ + W P LL DP + ++A K Sbjct: 207 CNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKK 266 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 +K++ A + +R+ IQR ++ + +S + EN+QVF F+LS E+M T+ N+N+R Sbjct: 267 NKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFR--- 323 Query: 301 VLQSSHLED---YPFNAEY 316 L + L D YPF EY Sbjct: 324 YLPAEFLVDHPEYPFVEEY 342 >1AFS-A nrPDB Length = 323 Score = 290 bits (741), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 145/315 (46%), Positives = 200/315 (63%), Gaps = 4/315 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V L+ +P++G GT K +V +A K+AID G+RH D AY+Y+ E EVG+AI+ Sbjct: 8 VALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRS 67 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI++ VKRED+F SKLW TF LVR EKTLK +L Y+D+Y+IH+P + GD Sbjct: 68 KIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDI 127 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 FP+D+ G + D WEAME+ D GL K++GVSNF+ Q+E++LNKPGLKYKPV Sbjct: 128 FFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPV 187 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240 NQVECH YL Q K++ YC SK I + +Y LGS D+ W + P LL+DP + IA K Sbjct: 188 CNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCAIAKK 247 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 +K+T A V +R+ +QR V+ + +S RI E QVF+F+L+ E+M + NRN+R N Sbjct: 248 YKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNFRYNN 307 Query: 301 VLQSSHLEDYPFNAE 315 ++PF E Sbjct: 308 AKYFDDHPNHPFTDE 322 >2HE8-A nrPDB Length = 323 Score = 278 bits (712), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 137/308 (44%), Positives = 192/308 (62%), Gaps = 4/308 (1%) Query: 13 MPIVGLGT---WKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVK 69 +P++G GT + P K KE K+AIDAG+ H D A VY E VGEAI+ KI + V+ Sbjct: 16 IPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIADGTVR 75 Query: 70 REDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKG 129 RED+F SK+W T LVR + E++L+ L+ Y+D+YLIH+P K G++ FP D+ G Sbjct: 76 REDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENFPVDEHG 135 Query: 130 NAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHP 189 I + WEAME+ D GL K++GVSNF++ Q+E +LNKPGLKYKPV NQVECHP Sbjct: 136 KLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHP 195 Query: 190 YLTQEKLIQYCHSKGITVTAYSPLGSPDR-PWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248 YL Q KL+ +C SK I + AY LG+ W P LL++P + +A K+ +T A + Sbjct: 196 YLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALI 255 Query: 249 LIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLE 308 +R+ +QR ++V+ S+ RI EN+QVF+F+LS E+M + NRN R Sbjct: 256 ALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAAIFKGHP 315 Query: 309 DYPFNAEY 316 ++PF EY Sbjct: 316 NWPFLDEY 323 >3H7U-A nrPDB Length = 335 Score = 239 bits (610), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 129/291 (44%), Positives = 175/291 (60%), Gaps = 22/291 (7%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 TF +L+T AK P VGLGTW++ G V +AV A+ GYRHIDCA +Y NE E+G +++ Sbjct: 26 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 85 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSG--- 119 +++ VKREDLFI SKLW T + V +A +TLKDL+L Y+D+YLIHWP K G Sbjct: 86 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 145 Query: 120 ---DDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGL 176 ++L P D W+AME L D G +A+GVSNFS ++ LL Sbjct: 146 IKPENLLPVD-----------IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA-- 192 Query: 177 KYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKE 236 + P NQVECHP Q KL ++C SKG+ ++AYSPLGSP W K + +L++P + Sbjct: 193 RVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNM 249 Query: 237 IAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287 +A K K+ AQV +R+ +Q V+PKS RI EN VFD+ + D A Sbjct: 250 VAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFA 300 >5JH1-A nrPDB Length = 309 Score = 232 bits (592), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 128/281 (45%), Positives = 173/281 (61%), Gaps = 11/281 (3%) Query: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66 L+T AK+P VGLG+W+S G V AV A+ AGYRHIDCA VY NE E+G A+++ +E Sbjct: 6 LNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKKLFEEG 65 Query: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126 VKRED+FI SKLW V +A +L DL+L YLD+YLIHWP K G + P+ Sbjct: 66 VVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGTNTSPE- 124 Query: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186 N + F W AME+L D G +A+GVSNFS ++ LL + P +QVE Sbjct: 125 ---NFV--TPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVA--RVPPAVDQVE 177 Query: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAA 246 CHP Q KL +C S G+ +TAYSPLGSP W + ++L++P I IA K KT+A Sbjct: 178 CHPGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWM---NGNVLKEPIIISIAEKLGKTSA 234 Query: 247 QVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287 QV +R++IQ V+PKS RI +N+ V+D+ + D+ +A Sbjct: 235 QVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLA 275 >3KRB-A nrPDB Length = 334 Score = 231 bits (588), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 131/304 (43%), Positives = 184/304 (60%), Gaps = 23/304 (7%) Query: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE--KIQEKAVKRE 71 P +G GTW++P V+ AV+ A+ GYRHIDCAYVYQNE +G A + K +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 72 DLFIVSKLWPTFFERP-LVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD--DLFPKDDK 128 D++I SKLW + RP LVR+ +KT+ DL++ YLD++L+HWP F D DLFPKD + Sbjct: 86 DVWITSKLW-NYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAE 144 Query: 129 GNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECH 188 G A+ K D W AME+LV+EGLVK +GVSN++ + LLN K KP+ NQ+E H Sbjct: 145 GRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNY--AKIKPLVNQIEIH 202 Query: 189 PYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS------LLEDPKIKEIAAKHK 242 P+ + +++C GI VTAYSP+G +A P DPS +LE +K IA Sbjct: 203 PWHPNDATVKFCLDNGIGVTAYSPMGG---SYADPRDPSGTQKNVILECKTLKAIADAKG 259 Query: 243 KTAAQVLIRFHIQR----NVIVIPKSVTPARIVENIQVFDFKLSDEEMATI--LSFNRNW 296 + V + +H+++ VIPKS TPARI N + + +LSD++M I + N+ Sbjct: 260 TSPHCVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRI 319 Query: 297 RACN 300 R C+ Sbjct: 320 RFCD 323 >3WCZ-A nrPDB Length = 308 Score = 224 bits (572), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 125/316 (39%), Positives = 184/316 (58%), Gaps = 22/316 (6%) Query: 2 ATFVELSTKAKMPIVGLGTWKS------PLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55 A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V Sbjct: 5 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 64 Query: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P Sbjct: 65 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 124 Query: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ Sbjct: 125 TK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 173 Query: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIK 235 ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + Sbjct: 174 IR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLT 231 Query: 236 EIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRN 295 +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A I FN+N Sbjct: 232 ALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKN 291 Query: 296 WRACNVLQSSHLEDYP 311 R ++ S +DYP Sbjct: 292 HRVIDI---SDWKDYP 304 >3H7R-A nrPDB Length = 331 Score = 221 bits (562), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 127/303 (41%), Positives = 180/303 (59%), Gaps = 15/303 (4%) Query: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA +Y NE E+G +++ I Sbjct: 27 FFELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 82 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 + VKRE+LFI SKLW V KA EKTL+DL++ Y+D+YLIHWP K + L Sbjct: 83 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 141 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 P + + K W+AME L D G +A+GVSNFS ++ LLN + P N Sbjct: 142 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 195 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 QVECHP Q+ L + C SKG+ ++ YSPLGS + + + +L++P + E+A K K Sbjct: 196 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGK 252 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQ 303 T AQV +R+ +Q V+PKS + AR+ EN+ VFD+ + E++ T S + C + Sbjct: 253 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIP-EDLFTKFSNIPQEKFCRATE 311 Query: 304 SSH 306 +H Sbjct: 312 FAH 314 >4F40-A nrPDB Length = 288 Score = 219 bits (559), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 127/296 (42%), Positives = 171/296 (57%), Gaps = 29/296 (9%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKE-AVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V LS KMP GLG W+SP G+V E AVK A+ AGYRHID A +Y+NE VG ++ Sbjct: 11 AMVTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA 70 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 V RED+FI +KLW T AFE++ + L + Y+D+YLIHWP+G D Sbjct: 71 S----GVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG----KD 122 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 + K+ K +LD+W A E+L E V+A+GVSNF +E +L P+ Sbjct: 123 ILSKEGK--------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAM--CTVTPM 172 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 NQVE HP Q L +C +K I V A+SPLG LL +P + I AK+ Sbjct: 173 VNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQG----------KLLSNPILSAIGAKY 222 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 KTAAQV++R++IQ+N+I IPKSV RI EN +FDF+L E++ +I + N N R Sbjct: 223 NKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 278 >1VBJ-A nrPDB Length = 281 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 123/294 (41%), Positives = 163/294 (55%), Gaps = 37/294 (12%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKV-AIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 ++LS MP++G G WK G E + AI +GYRHID A +Y+NE G AI Sbjct: 12 LKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRAIASC- 70 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 V RE+LF+ +KLW + AFEK++K L L Y+D+YLIHWP Sbjct: 71 ---GVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWP---------- 117 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 GK F+D W+A E+L + V+A+GVSNF IE+LL K P+ N Sbjct: 118 ----------GKDKFIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKH--CKVAPMVN 165 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 Q+E HP L Q+ L +YC SK I VTA+SPLG L+ED ++K I K+ K Sbjct: 166 QIELHPLLNQKALCEYCKSKNIAVTAWSPLGQG----------HLVEDARLKAIGGKYGK 215 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 TAAQV++R+ IQ VI IPKS ARI EN +FDF+L+ E++ I N R Sbjct: 216 TAAQVMLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHR 269 >4GIE-A nrPDB Length = 290 Score = 214 bits (544), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 119/296 (40%), Positives = 172/296 (58%), Gaps = 38/296 (12%) Query: 5 VELSTKAKMPIVGLGTWKSPLG-KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 V L +MP +GLG W++ G + AV+ AI+AGYRHID AY+Y NE VG+ I+E Sbjct: 16 VTLHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVGQGIRES- 74 Query: 64 QEKAVKREDLFIVSKLWPT--FFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 V RE++++ +K+W + +E+ L AFE++ + L L Y+D+YLIHWP Sbjct: 75 ---GVPREEVWVTTKVWNSDQGYEKTLA--AFERSRELLGLEYIDLYLIHWP-------- 121 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 GK F+D W+A+E+L +E V+A+GVSNF + +L K +P+ Sbjct: 122 ------------GKKKFVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFKS--CKIRPM 167 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 NQVE HP Q L ++C I +TA+SPLGS E+ +L++ + EIA KH Sbjct: 168 VNQVELHPLFQQRTLREFCKQHNIAITAWSPLGSG-------EEAGILKNHVLGEIAKKH 220 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 K+ AQV+IR+ IQ ++ IPKS RI EN V+DFKL++EEM I N + R Sbjct: 221 NKSPAQVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKR 276 >5ZCM-A nrPDB Length = 341 Score = 208 bits (530), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 120/306 (39%), Positives = 173/306 (56%), Gaps = 12/306 (3%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++L++ +MP+VG G WK + V AI GYR D A Y N E+GE I + Sbjct: 24 IKLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRALD 83 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--SGDDL 122 E V R++LFI SKLW ++ + V A +K L D+KL Y+D++LIH+P FK ++ Sbjct: 84 EGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEEK 143 Query: 123 FPK----DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178 +P D N L+ W+AME+L G K++G+SNFS I LL G + Sbjct: 144 YPPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLR--GAEI 201 Query: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD----RPWAKPEDPSLLEDPKI 234 KP Q+E HPYL Q +LI+Y S+GI +TAYS G + + P+L E I Sbjct: 202 KPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKTI 261 Query: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294 IA K+KKT AQVL+R+ QR++ +IPKS P R+++N++V DF LS E+ I ++ Sbjct: 262 TSIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLDQ 321 Query: 295 NWRACN 300 + R N Sbjct: 322 DLRFNN 327 >1QWK-A nrPDB Length = 317 Score = 206 bits (525), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 118/295 (40%), Positives = 166/295 (56%), Gaps = 23/295 (7%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++LS +MP++GLGTW+S +V AVK A+ AGYR ID A VYQNE +G AI+E ++ Sbjct: 8 IKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELLE 67 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124 E VKRE+LFI +K W + ++LK L+L Y+D+YL H P F Sbjct: 68 EGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAF-------- 119 Query: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN- 183 DD I D W + + GL KA+GVSN+++ QI + L L PV N Sbjct: 120 NDDMSEHIASPVE--DVWRQFDAVYKAGLAKAVGVSNWNNDQISRAL---ALGLTPVHNS 174 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR-----PWAKPED----PSLLEDPKI 234 QVE H Y Q + +C I+VT+Y+ LGSP R P + D PS L+D + Sbjct: 175 QVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNV 234 Query: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI 289 +A K KT AQVL+R+ + R ++PKS+ RI EN +VFDF L++E++A + Sbjct: 235 LALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKL 289 >1K8C-A nrPDB Length = 322 Score = 202 bits (514), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 124/313 (39%), Positives = 168/313 (53%), Gaps = 18/313 (5%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++LS+ MP +G G WK E V AI AGYR D A Y NE EVG+ ++ I Sbjct: 8 IKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAID 67 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--SGDDL 122 E VKRE++F+ SKLW + + V A KTL DLK+ Y+D++LIH+P FK ++ Sbjct: 68 EGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEK 127 Query: 123 FPK----DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178 +P D N + L+ W+A+E+LV G +K++GVSNF + LL G Sbjct: 128 YPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLR--GATI 185 Query: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD----RPWAKPEDPSLLEDPKI 234 KP QVE HPYL Q KLI++ G+T+TAYS G P+L I Sbjct: 186 KPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTI 245 Query: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI----- 289 K IAAK+ KT A+VL+R+ QR + VIPKS P R+V+N F L+ E+ I Sbjct: 246 KAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIAKLDI 305 Query: 290 -LSFNRNWRACNV 301 L FN W N+ Sbjct: 306 GLRFNDPWDWDNI 318 >5Z6T-A nrPDB Length = 343 Score = 202 bits (514), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 124/308 (40%), Positives = 171/308 (55%), Gaps = 22/308 (7%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++L++ MP VG G WK + E + AI GYR D A Y NE VG +++ I Sbjct: 29 IKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAID 88 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124 E VKREDLF+ SKLW + V KA +TL DL++ Y+D++LIH+P FK P Sbjct: 89 EGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFK----FVP 144 Query: 125 KDDK---GNAIGGKATF-------LDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174 ++K G G F L+ W+A+E+LV G ++++GVSNF + LL Sbjct: 145 LEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLR-- 202 Query: 175 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-----DRPWAKPEDPSLL 229 G KP QVE HPYL Q +LI++ S+GI VTAYS G ++ A P L Sbjct: 203 GATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSP-LF 261 Query: 230 EDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI 289 E+ IK IAAKH K+ AQVL+R+ QR + +IPKS T R++EN V F L +++ A I Sbjct: 262 ENETIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADI 321 Query: 290 LSFNRNWR 297 + N R Sbjct: 322 AKLDINLR 329 >2BGQ-A nrPDB Length = 344 Score = 197 bits (502), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 115/290 (39%), Positives = 165/290 (56%), Gaps = 23/290 (7%) Query: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAI-DAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65 L + MP VGLGTW++ +V+ AI +AGYRH+D A Y E EVG+ ++ + E Sbjct: 42 LKSGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAM-E 99 Query: 66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125 + R+DLF+ SK+W T VR A E TLKDL+L Y+D+Y IHWP K G + P+ Sbjct: 100 AGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPPE 159 Query: 126 DDKGNAIGGKATFLD---AWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 G+ D W+ ME LV +GLVK +GV N++ ++ +LL K P Sbjct: 160 -------AGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSA--KIPPAV 210 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 Q+E HP +K+ + C GI +TAYSPLGS ++ +L DP ++++A K Sbjct: 211 CQMEMHPGWKNDKIFEACKKHGIHITAYSPLGSSEK--------NLAHDPVVEKVANKLN 262 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSF 292 KT QVLI++ +QR VIPKS RI ENIQVF +++ +E+ + S Sbjct: 263 KTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSI 312 >1MZR-A nrPDB Length = 296 Score = 193 bits (491), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 106/295 (35%), Positives = 171/295 (57%), Gaps = 34/295 (11%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 T ++L MP +GLG W++ +V A++ A++ GYR ID A Y+NE VG+A++ Sbjct: 26 TVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA 85 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 +V RE+LFI +KLW +RP R+A +LK L+L Y+D+YL+HWP Sbjct: 86 ----SVNREELFITTKLWNDDHKRP--REALLDSLKKLQLDYIDLYLMHWP--------- 130 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 P D +++AW+ M EL EGL+K++GV NF +++L+++ G+ PV Sbjct: 131 VPAIDH---------YVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVT--PVI 179 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 NQ+E HP + Q +L + + I ++SPL + + + I+++A K+ Sbjct: 180 NQIELHPLMQQRQLHAWNATHKIQTESWSPLAQGGK--------GVFDQKVIRDLADKYG 231 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 KT AQ++IR+H+ ++VIPKSVTP+RI EN V+DF+L +E+ I ++ R Sbjct: 232 KTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKR 286 >4IJC-A nrPDB Length = 344 Score = 192 bits (487), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 113/307 (36%), Positives = 179/307 (58%), Gaps = 28/307 (9%) Query: 4 FVELSTKAKMPIVGLGTWK--SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 + L+ ++P +GLGT L + K+AVK AI AGYRHID A+ Y+ E VGEAI+E Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK---- 117 +++ ++KREDLFI +K+WP ++ V ++ ++LK L L Y+D+ L HWP F+ Sbjct: 84 LLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 118 ----SGDDLFPKDDKGNAI-GGKATFLDAWEAMEELV---DEGLVKALGVSNFSHFQIEK 169 SG P DD G + +L+ ++ +E++ ++ V+A+GVSNFS +E+ Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 Query: 170 LLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLL 229 L+ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P L Sbjct: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------L 251 Query: 230 EDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI 289 + P +K++A K+ T +LI +HI++ IVIP+S+ P RI +I+ L+ +E+ + Sbjct: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQEL 309 Query: 290 LSFNRNW 296 F + Sbjct: 310 NDFGEKY 316 >3D3F-A nrPDB Length = 275 Score = 189 bits (479), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 120/294 (40%), Positives = 168/294 (57%), Gaps = 37/294 (12%) Query: 5 VELSTKAKMPIVGLGTWKSPLG-KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 V+L +MP GLG +K G + E+VK AI GYR ID A +Y+NE VG I+E Sbjct: 8 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKES- 66 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 V RE+LFI SK+W AFEK+L+ L+L YLD+YLIHWP Sbjct: 67 ---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 113 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 GK + D W A+E+L +G ++A+GVSNF +E+LL +K P+ N Sbjct: 114 ----------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIK--PMVN 161 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 QVE HP LTQ++L YC +GI + A+SPL LL++ + +IA KH K Sbjct: 162 QVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQG----------QLLDNEVLTQIAEKHNK 211 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 + AQV++R+ +Q V+ IPKS+ RI+EN +FDF+LS E+M I + N++ R Sbjct: 212 SVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDER 265 >1VP5-A nrPDB Length = 298 Score = 182 bits (463), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 106/294 (36%), Positives = 164/294 (55%), Gaps = 31/294 (10%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 V L+ +MPI+G G ++ P K +E V AI GYR ID A Y NE VG AI+ I Sbjct: 18 VTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAID 77 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124 E V+RE+LF+ +KLW + +KAFEK+LK L+L Y+D+YLIH P G D+ Sbjct: 78 EGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG-----DVHC 132 Query: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184 AW+AMEE+ +GLV+A+GVSNF ++ L+ + P NQ Sbjct: 133 ----------------AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEI--VPAVNQ 174 Query: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244 +E HP+ +++ I++ + I A+ P + ++ ++ ++ IA K+ KT Sbjct: 175 IEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRK--------NIFQNGVLRSIAEKYGKT 226 Query: 245 AAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298 AQV++R+ Q+ ++ IPK+V R+ ENI +FDF+L+ E+M I + + A Sbjct: 227 VAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQSA 280 >3UP8-A nrPDB Length = 298 Score = 168 bits (426), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 102/296 (34%), Positives = 163/296 (55%), Gaps = 39/296 (13%) Query: 8 STKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKA 67 S A +P +G GT++ +V + A+ G+RH+D A +Y NE EVGEA IQ+ Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEA----IQKSG 84 Query: 68 VKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDD 127 + R D+F+ +K+W + + +++L+ L+ ++D+ L+HWP G D+ P + Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWP-----GSDV-PMAE 138 Query: 128 KGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV-TNQVE 186 + IG A+ E+ + G V+ +G+SNF+ Q+E+ L P+ TNQVE Sbjct: 139 R---IG----------ALNEVRNAGKVRHIGISNFNTTQMEEAAR---LSDAPIATNQVE 182 Query: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAA 246 HPYL Q K++Q G+++T+Y + + P DP + EI +H KTAA Sbjct: 183 YHPYLDQTKVLQTARRLGMSLTSYYAMANGKVP----------ADPLLTEIGGRHGKTAA 232 Query: 247 QVLIRFHI-QRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR-NWRACN 300 QV +R+ + Q++VIV+ K+ T AR+ EN +FDF L+ EEMA + R N R N Sbjct: 233 QVALRWLVQQQDVIVLSKTATEARLKENFAIFDFALTREEMAAVRELARPNGRIVN 288 >4MHB-A nrPDB Length = 297 Score = 157 bits (397), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 97/292 (33%), Positives = 153/292 (52%), Gaps = 40/292 (13%) Query: 5 VELSTKAKMPIVGLGTWK-SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 V+L+ MP++G G ++ + + + AV AI+ GYR ID A YQNE +VG A++ Sbjct: 18 VKLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNALKLS- 76 Query: 64 QEKAVKREDLFIVSKLW--PTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 + R++LFI +KLW T++E + FE++L L+L Y+D+YLIH P G G Sbjct: 77 ---GIARDELFITTKLWLQDTYYEG--AKAQFERSLNRLQLDYVDLYLIHQPYGDVHG-- 129 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 AW AMEEL G ++A+GVSNF ++ L+ K P Sbjct: 130 -------------------AWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFN--KIIPA 168 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 NQ+E +P+ Q + + S+GI A++P L ++P + I K+ Sbjct: 169 VNQIEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRN--------GLFQNPVLTAIGEKY 220 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFN 293 K+ QV++R+ QR ++ + KSV R+ ENI + DF+LS E+M I + + Sbjct: 221 GKSVGQVVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALD 272 >4OTK-A nrPDB Length = 318 Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 100/296 (33%), Positives = 149/296 (50%), Gaps = 40/296 (13%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 + L+ + MP++GLG + + + AV A++ G R ID AY Y NE VG AI Sbjct: 49 ITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAIAAS-- 106 Query: 65 EKAVKREDLFIVSKLWP--TFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 V RE+LF+ +KL F R ++A +L L L Y+D+YLIHWP Sbjct: 107 --GVAREELFVTTKLATPDQGFTRS--QEACRASLDRLGLDYVDLYLIHWPA-------- 154 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY-KPV 181 P K ++DAW M + EG +++GVSNF+ IE L++ L + P Sbjct: 155 -PPVGK---------YVDAWGGMIQSRGEGHARSIGVSNFTAENIENLID---LTFVTPA 201 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 NQ+E HP L Q++L + + +Y PL LL++P + IA+++ Sbjct: 202 VNQIELHPLLNQDELRKANAQHTVVTQSYCPLALG----------RLLDNPTVTSIASEY 251 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 KT AQVL+R+++Q V+ +S P RI N VFDF+L+ E M + N R Sbjct: 252 VKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTR 307 >1A80-A nrPDB Length = 277 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 93/287 (32%), Positives = 144/287 (50%), Gaps = 32/287 (11%) Query: 7 LSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEK 66 L+ +P +G G +K P + AV+ A++ GYRHID A +Y NE E + I Sbjct: 7 LNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNE----EGVGAAIAAS 62 Query: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126 + R+DLFI +KLW + A ++L L L +D+YL+HWP P Sbjct: 63 GIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPT---------PAA 113 Query: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186 D ++ AWE M EL GL +++GVSN +E+++ G+ P NQ+E Sbjct: 114 DN---------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVV--PAVNQIE 162 Query: 187 CHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAA 246 HP Q ++ + + + + ++ PLG L + AA H KT A Sbjct: 163 LHPAYQQREITDWAAAHDVKIESWGPLGQGKY--------DLFGAEPVTAAAAAHGKTPA 214 Query: 247 QVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFN 293 Q ++R+H+Q+ +V PKSV R+ EN+ VFDF L+D E+A I + + Sbjct: 215 QAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMD 261 >4H8N-A nrPDB Length = 310 Score = 143 bits (361), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 99/301 (32%), Positives = 158/301 (52%), Gaps = 37/301 (12%) Query: 3 TFVELSTKAKMPIVGLGT-WKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55 TF S K +G GT WK ++ + + + + G+RHID A Y + EV Sbjct: 13 TFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEV 72 Query: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKA----FEKTLKDLKLSYLDVYLIH 111 GEA++ V RED+++ +K P + K+ +K L L + Y+D++LIH Sbjct: 73 GEALKRT----DVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLIH 128 Query: 112 WPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLL 171 P F ++ + T AWEA+ E G V+ +G+SN + +EKL Sbjct: 129 SP---------FFTTEQTHGY----TLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLF 175 Query: 172 N-KPGLKYKPVTNQVECHPYLTQE--KLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228 P +Y PV NQ+E HP+L + ++++C GI V A+SPL P A+ E +L Sbjct: 176 AASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA----PLARVETNAL 231 Query: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288 E +K +A K+KKT AQVL+R+ +QR ++ + S +R+ E++ +FDF+L+DEE+ Sbjct: 232 AE--TLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNE 289 Query: 289 I 289 I Sbjct: 290 I 290 >3WG6-A nrPDB Length = 307 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 84/309 (27%), Positives = 144/309 (46%), Gaps = 58/309 (18%) Query: 6 ELSTKAKMPIVGLGTWKSPLGKVKE--------AVKVAIDAGYRHIDCAYVYQNEHEVGE 57 +LS K+P V GT + +++A+ +G+RHID A +Y E+G Sbjct: 12 KLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIGI 71 Query: 58 AIQEKIQEKAVKREDLFIVSKLWP---------TFFERPLVRKAFEKTLKDLKLSYLDVY 108 A++ + R+D+FI K + + P A + L+DL L Y+D+Y Sbjct: 72 ALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPY--NALKADLEDLGLEYVDLY 125 Query: 109 LIHWP------QGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNF 162 LIH+P GF ++AW +E +EGL + +GVSNF Sbjct: 126 LIHFPYISEKSHGFD--------------------LVEAWRYLERAKNEGLARNIGVSNF 165 Query: 163 SHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK--LIQYCHSKGITVTAYSPLGSPDRPW 220 + ++ +L+ PV NQ+E YL + +++Y +GI + AY PLG + Sbjct: 166 TIENLKSILD-ANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGR 224 Query: 221 AKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFK 280 P D L +++ K+K+ Q+L+R+ +QR ++ I + RI + +++FDF+ Sbjct: 225 PGPLDKVL------SKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFE 278 Query: 281 LSDEEMATI 289 L E+ I Sbjct: 279 LDKEDEDQI 287 >1PYF-A nrPDB Length = 312 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 75/295 (25%), Positives = 127/295 (43%), Gaps = 61/295 (20%) Query: 29 KEAVKVAIDAGYRHIDCAYVY---QNEHEVGEAIQEKIQEKAVKREDLFIVSKLWP---- 81 KE V+ AI G +D AY+Y ++E +GE ++E RED+ I +K Sbjct: 38 KELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLRE------FNREDVVIATKAAHRKQG 91 Query: 82 ---TFFERP-LVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137 F P ++K+ +++LK L Y+D++ IH+P D+ PKD Sbjct: 92 NDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP------DEHTPKD----------- 134 Query: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197 +A A+ E+ G ++++GVSNFS Q+ K NK GL + + ++ Sbjct: 135 --EAVNALNEMKKAGKIRSIGVSNFSLEQL-KEANKDGL-VDVLQGEYNLLNREAEKTFF 190 Query: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDP---------------------KIKE 236 Y I+ Y PL S ED + E K+ Sbjct: 191 PYTKEHNISFIPYFPLVSGLLAGKYTEDTTFPEGDLRNEQEHFKGERFKENIRKVNKLAP 250 Query: 237 IAAKHKKTAAQVLIRFHIQRNV--IVIPKSVTPARIVENIQVFDFKLSDEEMATI 289 IA KH +++ +++ R I+IP + ++++NI+ D LS E+++ I Sbjct: 251 IAEKHNVDIPHIVLAWYLARPEIDILIPGAKRADQLIDNIKTADVTLSQEDISFI 305 >1PZ1-A nrPDB Length = 333 Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 64/220 (29%), Positives = 95/220 (43%), Gaps = 51/220 (23%) Query: 16 VGLGTWKSPLGKVK----------EAVKVAIDAGYRHIDCAYVY---QNEHEVGEAIQEK 62 +GLGTW +G E ++ A+D G ID A Y Q+E VG+AI+E Sbjct: 16 IGLGTWA--IGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGKAIKEY 73 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKA--------FEKTLKDLKLSYLDVYLIHWPQ 114 + KR+ + + +K + L R A E +LK L+ Y+D+Y +HWP Sbjct: 74 M-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLYQVHWP- 127 Query: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN-K 173 D L P ++ E M+EL D G ++A+GVSNFS Q++ Sbjct: 128 -----DPLVPIEETA-------------EVMKELYDAGKIRAIGVSNFSIEQMDTFRAVA 169 Query: 174 PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213 P +P N E +E ++ Y IT Y L Sbjct: 170 PLHTIQPPYNLFERE---MEESVLPYAKDNKITTLLYGSL 206 >1LQA-A nrPDB Length = 346 Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 12/138 (8%) Query: 84 FERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS--GDDLFPKDDKGNAIGGKATFLDA 141 +R +R+A +LK L+ YLD+Y +HWPQ + G + D A+ + LD Sbjct: 105 LDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAV----SLLDT 160 Query: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK-----L 196 +A+ E G ++ +GVSN + F + + L+ P ++ +PY + L Sbjct: 161 LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQ-NPYSLLNRSFEVGL 219 Query: 197 IQYCHSKGITVTAYSPLG 214 + +G+ + AYS LG Sbjct: 220 AEVSQYEGVELLAYSCLG 237 >4R9O-A nrPDB Length = 301 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 51/183 (27%), Positives = 76/183 (41%), Gaps = 32/183 (17%) Query: 18 LGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVY---QNEHEVGEAI------QEKIQ--EK 66 L W ++ ++ +D G +D A +Y Q E GEA+ +EK+Q K Sbjct: 27 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTK 86 Query: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKD 126 +KL +R + + E++LK+L YLD+ LIH P DD+ Sbjct: 87 CGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPDPLMDADDVA--- 143 Query: 127 DKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186 EA + L G V+ GVSNF+ Q L ++ L + TNQVE Sbjct: 144 ----------------EAFQHLHQSGKVRHFGVSNFTPAQFTLLQSR--LPFTLATNQVE 185 Query: 187 CHP 189 P Sbjct: 186 ISP 188 >3N6Q-A nrPDB Length = 346 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 66/329 (20%), Positives = 133/329 (40%), Gaps = 75/329 (22%) Query: 12 KMPIVGLGTWKS-----PLGKVKEAVKVAIDAGYRHIDCAYVY-----QNEHEVGEAIQE 61 ++P + LG W + L + ++ A D G H D A Y E G ++E Sbjct: 24 RLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLRE 83 Query: 62 KIQEKAVKREDLFIVSK----LWPTFFERPLVRK----AFEKTLKDLKLSYLDVYLIHWP 113 A R++L I +K +WP + RK + +++LK + L Y+D++ H Sbjct: 84 DF---AAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSH-- 138 Query: 114 QGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173 D+ P ++ +A+ V G +G+S++S + +K++ Sbjct: 139 ----RVDENTPMEETASALA-------------HAVQSGKALYVGISSYSPERTQKMVEL 181 Query: 174 ------PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL-----------GSP 216 P L ++P N + + ++ + L+ + G+ A++PL G P Sbjct: 182 LREWKIPLLIHQPSYNLL--NRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIP 239 Query: 217 DRPWAKPED-------PSLLEDPK------IKEIAAKHKKTAAQVLIRFHIQ--RNVIVI 261 E P +L + + E+A + ++ AQ+ + + ++ R V+ Sbjct: 240 QDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVL 299 Query: 262 PKSVTPARIVENIQVF-DFKLSDEEMATI 289 + ++ EN+Q + S +E+A I Sbjct: 300 IGASRAEQLEENVQALNNLTFSTKELAQI 328 >1OG6-A nrPDB Length = 298 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 75/184 (40%), Gaps = 34/184 (18%) Query: 18 LGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVS 77 L W ++ ++ +D G +D A +Y ++ A E ++ RE + IVS Sbjct: 24 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGG-YQCEAAFGEALKLAPHLRERMEIVS 82 Query: 78 K------------LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125 K + +R + K+ E++L +L +LD+ LIH P D++ Sbjct: 83 KCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVA-- 140 Query: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185 +A + L G V+ GVSNF+ Q L ++ L + TNQV Sbjct: 141 -----------------DAFKHLHQSGKVRHFGVSNFTPAQFALLQSR--LPFTLATNQV 181 Query: 186 ECHP 189 E P Sbjct: 182 EISP 185 >1GVE-A nrPDB Length = 327 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 43/200 (21%) Query: 31 AVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRE-DLFIVSKLWPTFFE--RP 87 +V+ + G+ ID A+VY N E I + + + I +K P F + +P Sbjct: 27 SVRAFLQRGHTEIDTAFVYANGQS--ETILGDLGLGLGRSGCKVKIATKAAPMFGKTLKP 84 Query: 88 L-VRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146 VR E +LK L+ +D++ +H+P D G I + +A Sbjct: 85 ADVRFQLETSLKRLQCPRVDLFYLHFP-------------DHGTPIE------ETLQACH 125 Query: 147 ELVDEGLVKALGVSNFSHFQIEK---LLNKPGL--------KYKPVTNQVECHPYLTQEK 195 +L EG LG+SN+ +++ + L K G Y +T QVE + Sbjct: 126 QLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVE-------TE 178 Query: 196 LIQYCHSKGITVTAYSPLGS 215 L G+ A++PL Sbjct: 179 LFPCLRHFGLRFYAFNPLAG 198 >5BVC-A nrPDB Length = 447 Score = 31.2 bits (69), Expect = 0.56, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 2/56 (3%) Query: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 D+ G G K AW+ ME LV + V H+ + K+ PGL Y+ V Sbjct: 352 DEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKV--SPGLNYRSV 405 >4EHI-A nrPDB Length = 534 Score = 31.2 bits (69), Expect = 0.68, Method: Compositional matrix adjust. Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 40 YRHIDCAYVYQNEHEVGE 57 ++HID +VYQN EVGE Sbjct: 383 FKHIDGGFVYQNSDEVGE 400 >4KM3-A nrPDB Length = 286 Score = 30.8 bits (68), Expect = 0.72, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 32/67 (47%) Query: 23 SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPT 82 +P +VK + + +A Y+ I+ A V ++G AIQE + + + + PT Sbjct: 145 TPSEEVKNLMDITKEAMYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPT 204 Query: 83 FFERPLV 89 E P+V Sbjct: 205 MHEEPMV 211 >3KRZ-A nrPDB Length = 337 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 5/56 (8%) Query: 89 VRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP-----KDDKGNAIGGKATFL 139 + KAF + K L+ DV IH G+ + L P KD+ GN+I +A FL Sbjct: 141 IVKAFGEAAKRANLAGYDVVEIHAAHGYLIHEFLSPLSNKRKDEYGNSIENRARFL 196 >5Y0V-A nrPDB Length = 578 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKL 281 + K A + ++RF ++R V V+P+ PA + E Q D + Sbjct: 253 YTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTV 293 >2BP1-A nrPDB Length = 360 Score = 28.5 bits (62), Expect = 4.4, Method: Compositional matrix adjust. Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 19/84 (22%) Query: 89 VRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEEL 148 VR E +LK L+ +D++ +H P D G + + A + L Sbjct: 120 VRSQLETSLKRLQCPQVDLFYLHAP-------------DHGTPVE------ETLHACQRL 160 Query: 149 VDEGLVKALGVSNFSHFQIEKLLN 172 EG LG+SN++ +++ ++ Sbjct: 161 HQEGKFVELGLSNYASWEVAEICT 184 >6EOJ-D nrPDB Length = 470 Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 11/47 (23%) Query: 197 IQYCHSKGITVTAYSPLG------SPDRP---W--AKPEDPSLLEDP 232 I Y H K IT +Y+P+G + DR W A+P DP+ +DP Sbjct: 345 IPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTRARPIDPNAYDDP 391 >2Z1K-A nrPDB Length = 475 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL-LEDPKIKEIAAKHKKTAAQVLIR 251 Q + H KG + AY+ + + W PE P L +E P ++E + A+ IR Sbjct: 138 QSPYRDWYHVKGFPLKAYTAHPNYEAWWGNPELPKLKVETPAVRE----YLLAVAEHWIR 193 Query: 252 FHIQRNVIVIPKSV 265 F + + +P + Sbjct: 194 FGVDGWRLDVPNEI 207 >4QNY-A nrPDB Length = 354 Score = 27.7 bits (60), Expect = 7.4, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 4/43 (9%) Query: 247 QVLIRFHIQRNVIVIPKSVTPARIVEN----IQVFDFKLSDEE 285 Q L HI + VI + +TPA I+ N +++ DF L+ EE Sbjct: 133 QALRALHIIHSAGVIHRDITPANILVNTNCDLKICDFGLAKEE 175 >3ZHS-A nrPDB Length = 868 Score = 27.3 bits (59), Expect = 9.3, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 3/56 (5%) Query: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVK---REDLFIVSKL 79 K+++ + V DA RH+ Y + E E IQE+++ K K E +I+SKL Sbjct: 72 KLRDILSVLRDAYCRHVGVEYTHILEPEQQRWIQERVETKHDKPTVAEQKYILSKL 127 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1ZUA-X nrPDB 512 e-146 4JQA-A nrPDB 482 e-137 1Q5M-A nrPDB 477 e-135 5JM5-A nrPDB 475 e-134 3RX4-A nrPDB 474 e-134 2FVL-A nrPDB 471 e-133 1C9W-A nrPDB 465 e-132 2ALR-A nrPDB 464 e-131 1DLA-A nrPDB 463 e-131 3G1R-A nrPDB 461 e-130 1FRB-A nrPDB 460 e-130 4GAC-A nrPDB 460 e-130 1HQT-A nrPDB 459 e-130 2HE8-A nrPDB 459 e-129 3O3R-A nrPDB 457 e-129 1AFS-A nrPDB 454 e-128 5UXF-A nrPDB 453 e-128 4HBK-A nrPDB 427 e-120 3H7U-A nrPDB 395 e-110 5JH1-A nrPDB 385 e-107 3WCZ-A nrPDB 383 e-107 5ZCM-A nrPDB 381 e-106 1K8C-A nrPDB 378 e-105 5Z6T-A nrPDB 377 e-105 3H7R-A nrPDB 376 e-105 4GIE-A nrPDB 365 e-101 4F40-A nrPDB 364 e-101 1VBJ-A nrPDB 359 e-100 3KRB-A nrPDB 354 3e-98 1QWK-A nrPDB 353 4e-98 1VP5-A nrPDB 351 2e-97 2BGQ-A nrPDB 346 6e-96 1MZR-A nrPDB 340 4e-94 4MHB-A nrPDB 325 1e-89 3D3F-A nrPDB 324 2e-89 4IJC-A nrPDB 320 5e-88 4OTK-A nrPDB 314 3e-86 1A80-A nrPDB 309 6e-85 3UP8-A nrPDB 295 1e-80 4H8N-A nrPDB 271 3e-73 3WG6-A nrPDB 264 3e-71 1PYF-A nrPDB 198 2e-51 3N6Q-A nrPDB 192 1e-49 1PZ1-A nrPDB 180 7e-46 4R9O-A nrPDB 164 4e-41 1OG6-A nrPDB 157 8e-39 1LQA-A nrPDB 157 9e-39 Sequences not found previously or not previously below threshold: 3EB3-A nrPDB 113 1e-25 2BP1-A nrPDB 78 6e-15 1GVE-A nrPDB 75 3e-14 2CLP-A nrPDB 75 6e-14 2C91-A nrPDB 71 6e-13 4EXA-A nrPDB 70 1e-12 1JPH-A nrPDB 32 0.40 2WK1-A nrPDB 32 0.43 2WUA-A nrPDB 31 0.78 1N7G-A nrPDB 31 0.84 5ZF1-A nrPDB 31 0.97 4WO8-A nrPDB 30 1.0 4EHI-A nrPDB 30 1.3 2PTS-A nrPDB 29 2.2 4L1C-A nrPDB 29 3.6 6J2N-S nrPDB 29 3.7 3JCK-A nrPDB 28 3.8 5XOR-A nrPDB 28 4.2 3Q3N-A nrPDB 28 6.3 2AXQ-A nrPDB 28 6.3 2ZVR-A nrPDB 28 6.3 4UEE-A nrPDB 28 7.4 5OM9-A nrPDB 28 8.2 >1ZUA-X nrPDB Length = 317 Score = 512 bits (1319), Expect = e-146, Method: Composition-based stats. Identities = 316/316 (100%), Positives = 316/316 (100%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ Sbjct: 2 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 61 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD Sbjct: 62 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 121 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP Sbjct: 122 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 181 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK Sbjct: 182 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 241 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN Sbjct: 242 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 301 Query: 301 VLQSSHLEDYPFNAEY 316 VLQSSHLEDYPFNAEY Sbjct: 302 VLQSSHLEDYPFNAEY 317 >4JQA-A nrPDB Length = 331 Score = 482 bits (1241), Expect = e-137, Method: Composition-based stats. Identities = 154/317 (48%), Positives = 208/317 (65%), Gaps = 4/317 (1%) Query: 4 FVELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 V+L+ MP++G GT+ + P K EAVK+AI+AG+ HID A+VY NE +VG AI+ Sbjct: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 KI + +VKRED+F SKLW LVR A E++LK+L+L Y+D+YLIH+P K G+ Sbjct: 67 SKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 ++ PKD+ G + WEAME+ D GL K++GVSNF+H +E +LNKPGLKYKP Sbjct: 127 EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKP 186 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD-RPWAKPEDPSLLEDPKIKEIAA 239 V NQVECHPY Q KL+ +C SK I + AYS LGS PW P P LLEDP + +A Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAK 246 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 KHK+T A + +R+ +QR V+V+ KS RI +N+QVF+F+L+ EEM I NRN R Sbjct: 247 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYL 306 Query: 300 NVLQSSHLEDYPFNAEY 316 + + +YPF+ EY Sbjct: 307 TLDIFAGPPNYPFSDEY 323 >1Q5M-A nrPDB Length = 322 Score = 477 bits (1228), Expect = e-135, Method: Composition-based stats. Identities = 160/316 (50%), Positives = 209/316 (66%), Gaps = 4/316 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V LS +P++G GT+ + P K EA K+AIDAG+RHID AY Y+NE EVG AI+ Sbjct: 7 VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRS 66 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI + VKRED+F SKLW TF LVR + E +LK+L+L Y+D+Y+IH+P K G + Sbjct: 67 KIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVE 126 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 + P D+ G AI WEAME+ D GL K++GVSNF+ Q+E +LNKPGLKYKPV Sbjct: 127 IIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 186 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP-WAKPEDPSLLEDPKIKEIAAK 240 NQVECHPYL Q KL+++C SKGI + AYS LGS P W P LLEDP I +A K Sbjct: 187 CNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKK 246 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 H++T A + +R+ +QR ++V+ KS T RI ENIQVF+F+L E+M I S NRN+R Sbjct: 247 HQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYVT 306 Query: 301 VLQSSHLEDYPFNAEY 316 + +YPF+ EY Sbjct: 307 ADFAIGHPNYPFSDEY 322 >5JM5-A nrPDB Length = 332 Score = 475 bits (1223), Expect = e-134, Method: Composition-based stats. Identities = 150/317 (47%), Positives = 204/317 (64%), Gaps = 4/317 (1%) Query: 4 FVELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 V+L+ MP++G GT+ + P K E K+AI+AG+RHID A++Y NE +VG AI+ Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 KI + +VKRED+F SKLW TF LVR A E +LK +L Y+D+YLIH P K G+ Sbjct: 67 SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 +L P D+ G I WEAME+ D GL K++GVSNF+ Q+E +LNKPGLKYKP Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAA 239 V NQVECHPY + KL+ +C SK I + AYS LGS D+ W P P LLEDP + +A Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 KHK+T A + +R+ +QR V+V+ KS RI +N+QVF+F+L+ E+M I +RN Sbjct: 247 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYF 306 Query: 300 NVLQSSHLEDYPFNAEY 316 N + +YP++ EY Sbjct: 307 NSDSFASHPNYPYSDEY 323 >3RX4-A nrPDB Length = 336 Score = 474 bits (1219), Expect = e-134, Method: Composition-based stats. Identities = 223/316 (70%), Positives = 263/316 (83%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 MA+ + L+ AKMPI+GLGTWKSP G+V EAVKVAID GYRHIDCA+VYQNE+EVG AIQ Sbjct: 21 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 80 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EK++E+ VKRE+LFIVSKLW T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G Sbjct: 81 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 140 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FP D+ GN + LD W AMEELVDEGLVKA+G+SNF+H Q+E +LNKPGLKYKP Sbjct: 141 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 200 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK Sbjct: 201 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 260 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 H KT AQVLIRF +QRN++VIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C Sbjct: 261 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 320 Query: 301 VLQSSHLEDYPFNAEY 316 +L + +DYPF+ E+ Sbjct: 321 LLSCTSHKDYPFHEEF 336 >2FVL-A nrPDB Length = 324 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 152/316 (48%), Positives = 208/316 (65%), Gaps = 4/316 (1%) Query: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 VEL+ MP++G GT+ + P + E K+AI+AG+RHID AY+Y NE +VG AI+ Sbjct: 9 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 68 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI + +VKRED+F SKLW TFF+ +V+ A E +LK L+L Y+D+YL+H+P K G+ Sbjct: 69 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 128 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 PKD+ G I WE ME+ D GL K++GVSNF++ Q+E +LNKPGLKYKPV Sbjct: 129 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPV 188 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD-RPWAKPEDPSLLEDPKIKEIAAK 240 NQVECHPYL Q KL+ +C SK I + A+S LG+ + W P P LLEDP + +A K Sbjct: 189 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKK 248 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HK+T A + +R+ +QR V+V+ KS RI ENIQVF+F+L+ E+M + NRN+R Sbjct: 249 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVV 308 Query: 301 VLQSSHLEDYPFNAEY 316 + DYPF+ EY Sbjct: 309 MDFLMDHPDYPFSDEY 324 >1C9W-A nrPDB Length = 315 Score = 465 bits (1197), Expect = e-132, Method: Composition-based stats. Identities = 262/315 (83%), Positives = 294/315 (93%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 +TFVELSTKAKMPIVGLGTW+SP G+VKEAVKVAIDAGYRHIDCAY Y NEHEVGEAIQE Sbjct: 1 STFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQE 60 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI+EKAV+REDLFIVSKLWPT FER L+++AF+KTL DLKL YLD+YLIHWPQG + G + Sbjct: 61 KIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 LFPKDD+GN + K TFLDAWE MEELVDEGLVKALGVSNF+HFQIE++LNKPGLK+KPV Sbjct: 121 LFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPV 180 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 TNQVECHPYLTQEKLI+YCHSKGITVTAYSPLGSP+RPWAKPEDPSLLEDPKIKEIAAKH Sbjct: 181 TNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301 KKT+AQVLIRFHIQRNV+VIPKSVTPARI EN QVFDF+LSD+EMATIL FNRNWRAC + Sbjct: 241 KKTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACLL 300 Query: 302 LQSSHLEDYPFNAEY 316 ++ ++E+YP++AEY Sbjct: 301 PETVNMEEYPYDAEY 315 >2ALR-A nrPDB Length = 324 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 158/325 (48%), Positives = 216/325 (66%), Gaps = 12/325 (3%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A+ V L T KMP++GLGTWKS G+VK AVK A+ GYRHIDCA +Y NE E+GEA++E Sbjct: 2 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 61 Query: 62 KIQEK-AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 + AV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD Sbjct: 62 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FPK+ G + + W+A+E LV +GLV+ALG+SNF+ QI+ +L+ ++ P Sbjct: 122 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 179 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P++P LLE+P + +A K Sbjct: 180 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 239 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC- 299 + ++ AQ+L+R+ +QR VI IPKS+TP+RI++NI+VFDF S EEM + + N+NWR Sbjct: 240 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 299 Query: 300 --------NVLQSSHLEDYPFNAEY 316 V + + YPFN Y Sbjct: 300 PMLTVDGKRVPRDAGHPLYPFNDPY 324 >1DLA-A nrPDB Length = 314 Score = 463 bits (1192), Expect = e-131, Method: Composition-based stats. Identities = 224/314 (71%), Positives = 261/314 (83%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 + + L T AKMPI+GLGTWKSP GKV EAVKVAID GYRHIDCA+VYQNE+EVG +QEK Sbjct: 1 SHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEK 60 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 +Q + VKREDLFIVSKLW T E+ LV+ A + TL+DLKL YLD+YLIHWP GFK G D Sbjct: 61 LQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDP 120 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 FP D GN + ++ F++ WEAMEELVDEGLVKA+GVSNF+H Q+EK+LNKPGLKYKP Sbjct: 121 FPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAV 180 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 NQ+E HPYLTQEKLI+YC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK+ Sbjct: 181 NQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYN 240 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVL 302 KT AQVLIRF +QRN+IVIPKSVTP RI EN QVFDF+LS E+M T+LS+NRNWR C ++ Sbjct: 241 KTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALM 300 Query: 303 QSSHLEDYPFNAEY 316 + +DYPF+ EY Sbjct: 301 SCASHKDYPFHEEY 314 >3G1R-A nrPDB Length = 346 Score = 461 bits (1187), Expect = e-130, Method: Composition-based stats. Identities = 161/317 (50%), Positives = 214/317 (67%), Gaps = 5/317 (1%) Query: 5 VELSTKAKMPIVGLGTWK----SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 + LS +PI+GLGT+ +P G +VKVAID GYRHID AY+YQNEHEVGEAI+ Sbjct: 30 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 89 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EKI E V+RED+F KLW T +VR E+TL+ L+L Y+D+Y+I P FK GD Sbjct: 90 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 149 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 +++P+D+ G + K+ WEAME D GLVK+LGVSNF+ Q+E +LNKPGLK+KP Sbjct: 150 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 209 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP-WAKPEDPSLLEDPKIKEIAA 239 V+NQVECHPY TQ KL+++C I +TAYSPLG+ P W P LL+D + + Sbjct: 210 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 269 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 ++ KTAAQ+++RF+IQR V+VIPKS RI EN Q+FDF L++EEM I + N+N R Sbjct: 270 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 329 Query: 300 NVLQSSHLEDYPFNAEY 316 +L +YPF+ EY Sbjct: 330 ELLMWRDHPEYPFHDEY 346 >1FRB-A nrPDB Length = 315 Score = 460 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 259/315 (82%), Positives = 292/315 (92%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 ATFVELSTKAKMPIVGLGTWKSP +VKEAVK AIDAGYRHIDCAY Y NE+EVGEAIQE Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 KI+EKAV+REDLFIVSKLWPT FE+ L+++AF+KTL DLKL YLD+YLIHWPQG + G + Sbjct: 61 KIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 LFPKDD+G + K TFL+AWE MEELVD+GLVKALGVSNF+HFQIE+LLNKPGLK+KPV Sbjct: 121 LFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 180 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 TNQVECHPYLTQEKLIQYCHSKGI+VTAYSPLGSPDRP AKPEDPSLLEDPKIKEIAAKH Sbjct: 181 TNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301 +KT+AQVLIRFHIQRNV+VIPKSVTP+RI ENIQVFDF+LSDEEMATILSFNRNWRAC + Sbjct: 241 EKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLL 300 Query: 302 LQSSHLEDYPFNAEY 316 ++ ++E+YP++AEY Sbjct: 301 PETVNMEEYPYDAEY 315 >4GAC-A nrPDB Length = 324 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 162/325 (49%), Positives = 217/325 (66%), Gaps = 12/325 (3%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A+ V L T KMP++GLGTWKS G+VK A+K A+ AGYRHIDCA VY NE E+GEA++E Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 62 KIQEK-AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 + AV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FPK+ G + + W+A+E LV +GLVKALG+SNF+ QI+ +L+ ++ P Sbjct: 122 NPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR--P 179 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 QVECHPYL Q +LI +CH++G+ VTAYSPLGS DR W P++P LLE+P + +A K Sbjct: 180 AVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEK 239 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC- 299 H ++ AQ+L+R+ +QR VI IPKS+ P+RI++NIQVFDF S EEM + + N+NWR Sbjct: 240 HGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIV 299 Query: 300 --------NVLQSSHLEDYPFNAEY 316 V + + YPFN Y Sbjct: 300 PMITVDGKRVPRDAGHPLYPFNDPY 324 >1HQT-A nrPDB Length = 326 Score = 459 bits (1182), Expect = e-130, Method: Composition-based stats. Identities = 160/325 (49%), Positives = 214/325 (65%), Gaps = 12/325 (3%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A+ V L T KMP++GLGTWKS G+VK A+K A+ GYRHIDCA ++ NE E+GEA+QE Sbjct: 4 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQE 63 Query: 62 KIQEK-AVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 + AV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD Sbjct: 64 TVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 123 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FPK+ G + D W+A+E LV +GLV+ALG+SNFS QI+ +L+ ++ P Sbjct: 124 NPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVR--P 181 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P +P LLE+P ++ +A K Sbjct: 182 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEK 241 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC- 299 + ++ AQ+L+R+ +QR VI IPKSVTP+RI +NIQVFDF S EEM + + N+N R Sbjct: 242 YNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLRFIV 301 Query: 300 --------NVLQSSHLEDYPFNAEY 316 V + + YPFN Y Sbjct: 302 PMLTVDGKRVPRDAGHPLYPFNDPY 326 >2HE8-A nrPDB Length = 323 Score = 459 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 139/317 (43%), Positives = 195/317 (61%), Gaps = 4/317 (1%) Query: 4 FVELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 V L+ +P++G GT + P K KE K+AIDAG+ H D A VY E VGEAI+ Sbjct: 7 CVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIR 66 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 KI + V+RED+F SK+W T LVR + E++L+ L+ Y+D+YLIH+P K G+ Sbjct: 67 SKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGE 126 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FP D+ G I + WEAME+ D GL K++GVSNF++ Q+E +LNKPGLKYKP Sbjct: 127 ENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKP 186 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR-PWAKPEDPSLLEDPKIKEIAA 239 V NQVECHPYL Q KL+ +C SK I + AY LG+ W P LL++P + +A Sbjct: 187 VCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAK 246 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 K+ +T A + +R+ +QR ++V+ S+ RI EN+QVF+F+LS E+M + NRN R Sbjct: 247 KYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYI 306 Query: 300 NVLQSSHLEDYPFNAEY 316 ++PF EY Sbjct: 307 PAAIFKGHPNWPFLDEY 323 >3O3R-A nrPDB Length = 316 Score = 457 bits (1175), Expect = e-129, Method: Composition-based stats. Identities = 247/316 (78%), Positives = 279/316 (88%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 M TFV+L TKAKMP+VGLGTWKSP G+VKEAVK AIDAGYRH DCAYVYQNE EVGEAIQ Sbjct: 1 MTTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQ 60 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 EKI+EKAV+REDLFIVSKLW TFFE+ L+++AF+KTL DLKL YLD+YLIHWPQG ++G Sbjct: 61 EKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGK 120 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + PKD +G + K+TFLDAWE MEELVD+GLVKALGVSNF+HFQIE+LLNKPGLK+KP Sbjct: 121 EFLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKP 180 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240 VTNQVECHPYLTQEKLIQYCHSKGI V AYSPLGSPDRP+AKPEDP +LE PKIKEIAAK Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAK 240 Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 HKKT AQVLIRFH+QRNV VIPKSVT + I ENIQVFDF+LS+E+MA ILS NRNWRAC Sbjct: 241 HKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACG 300 Query: 301 VLQSSHLEDYPFNAEY 316 + +S ED+PF+ EY Sbjct: 301 LFVTSDEEDFPFHEEY 316 >1AFS-A nrPDB Length = 323 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 145/319 (45%), Positives = 202/319 (63%), Gaps = 4/319 (1%) Query: 1 MATFVELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGE 57 ++ V L+ +P++G GT K +V +A K+AID G+RH D AY+Y+ E EVG+ Sbjct: 4 ISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQ 63 Query: 58 AIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK 117 AI+ KI++ VKRED+F SKLW TF LVR EKTLK +L Y+D+Y+IH+P + Sbjct: 64 AIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ 123 Query: 118 SGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLK 177 GD FP+D+ G + D WEAME+ D GL K++GVSNF+ Q+E++LNKPGLK Sbjct: 124 PGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLK 183 Query: 178 YKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKE 236 YKPV NQVECH YL Q K++ YC SK I + +Y LGS D+ W + P LL+DP + Sbjct: 184 YKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCA 243 Query: 237 IAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNW 296 IA K+K+T A V +R+ +QR V+ + +S RI E QVF+F+L+ E+M + NRN+ Sbjct: 244 IAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNF 303 Query: 297 RACNVLQSSHLEDYPFNAE 315 R N ++PF E Sbjct: 304 RYNNAKYFDDHPNHPFTDE 322 >5UXF-A nrPDB Length = 342 Score = 453 bits (1165), Expect = e-128, Method: Composition-based stats. Identities = 146/317 (46%), Positives = 204/317 (64%), Gaps = 4/317 (1%) Query: 4 FVELSTKAKMPIVGLGTWK---SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60 V+L+ +P +G GT+K P K EA +A+D GYRH+D AY YQ E E+G+AIQ Sbjct: 26 CVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQ 85 Query: 61 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120 I VKREDLF+ +KLW T F LV+ A EK+LK L+L Y+D+Y++H+P KSGD Sbjct: 86 SAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGD 145 Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180 + FP +++G ++ F D WE +EE D GLVK++GVSNF+H Q+E++LNKPGLKYKP Sbjct: 146 NDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKP 205 Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD-RPWAKPEDPSLLEDPKIKEIAA 239 V NQVECH YL Q KL+ YC SK I + AY LG+ + W P LL DP + ++A Sbjct: 206 VCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAK 265 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 K+K++ A + +R+ IQR ++ + +S + EN+QVF F+LS E+M T+ N+N+R Sbjct: 266 KNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYL 325 Query: 300 NVLQSSHLEDYPFNAEY 316 +YPF EY Sbjct: 326 PAEFLVDHPEYPFVEEY 342 >4HBK-A nrPDB Length = 344 Score = 427 bits (1098), Expect = e-120, Method: Composition-based stats. Identities = 158/312 (50%), Positives = 211/312 (67%), Gaps = 5/312 (1%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++++ +P++GLGTW SP G+V AVK A++ GYRH+DCAYVY+NE E+GEA++ + Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124 +KRED+FI SKLW TFF VRKA E+TLK+L+L+YLD+YLIHWP K G DLFP Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184 D G D W+ ME+LVDEGLVK++G+SNF+ QI+ +L + KP Q Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEH--CRIKPANLQ 215 Query: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244 +E H KL++Y S G+TVTAY+PLGSP P +LL P + EIA +HKKT Sbjct: 216 IEIHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHS---PGKVNLLTKPCVLEIAHRHKKT 272 Query: 245 AAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQS 304 AQVL+R+ +QR +IV+PKSVT RI EN QVFDF+LS+EEM + + + N R +LQ Sbjct: 273 PAQVLLRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELNTESLNERQFTLLQM 332 Query: 305 SHLEDYPFNAEY 316 S ++YPF EY Sbjct: 333 SGHQEYPFKEEY 344 >3H7U-A nrPDB Length = 335 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 129/311 (41%), Positives = 176/311 (56%), Gaps = 11/311 (3%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 TF +L+T AK P VGLGTW++ G V +AV A+ GYRHIDCA +Y NE E+G +++ Sbjct: 26 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 85 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 +++ VKREDLFI SKLW T + V +A +TLKDL+L Y+D+YLIHWP K G Sbjct: 86 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 145 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 ++ W+AME L D G +A+GVSNFS ++ LL + P Sbjct: 146 IKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 198 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 NQVECHP Q KL ++C SKG+ ++AYSPLGSP W K + +L++P + +A K Sbjct: 199 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLG 255 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVL 302 K+ AQV +R+ +Q V+PKS RI EN VFD+ + D A R Sbjct: 256 KSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEI-EQARLVTGS 314 Query: 303 QSSHLEDYPFN 313 H P+ Sbjct: 315 FLVHETLSPYK 325 >5JH1-A nrPDB Length = 309 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 132/315 (41%), Positives = 178/315 (56%), Gaps = 13/315 (4%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A L+T AK+P VGLG+W+S G V AV A+ AGYRHIDCA VY NE E+G A+++ Sbjct: 1 ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 +E VKRED+FI SKLW V +A +L DL+L YLD+YLIHWP K G + Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGTN 120 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 P++ F W AME+L D G +A+GVSNFS ++ LL + P Sbjct: 121 TSPEN------FVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVA--RVPPA 172 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 +QVECHP Q KL +C S G+ +TAYSPLGSP W +L++P I IA K Sbjct: 173 VDQVECHPGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGN---VLKEPIIISIAEKL 229 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301 KT+AQV +R++IQ V+PKS RI +N+ V+D+ + D+ +A + R Sbjct: 230 GKTSAQVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEI-KQARLLRG 288 Query: 302 LQSSHLED-YPFNAE 315 + E Y + E Sbjct: 289 NFIVNPESVYKTHEE 303 >3WCZ-A nrPDB Length = 308 Score = 383 bits (984), Expect = e-107, Method: Composition-based stats. Identities = 121/316 (38%), Positives = 180/316 (56%), Gaps = 19/316 (6%) Query: 2 ATFVELSTKAKMPIVGLGTWKS------PLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55 A ++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +V Sbjct: 5 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 64 Query: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P Sbjct: 65 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 124 Query: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 K D +L+ W+ M++ GL +++GVSNF+ QI +L++ Sbjct: 125 TKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 173 Query: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIK 235 ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + Sbjct: 174 IR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLT 231 Query: 236 EIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRN 295 +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A I FN+N Sbjct: 232 ALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKN 291 Query: 296 WRACNVLQSSHLEDYP 311 R ++ +YP Sbjct: 292 HRVIDISDWKDYPNYP 307 >5ZCM-A nrPDB Length = 341 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 120/306 (39%), Positives = 173/306 (56%), Gaps = 12/306 (3%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++L++ +MP+VG G WK + V AI GYR D A Y N E+GE I + Sbjct: 24 IKLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRALD 83 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--SGDDL 122 E V R++LFI SKLW ++ + V A +K L D+KL Y+D++LIH+P FK ++ Sbjct: 84 EGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEEK 143 Query: 123 FPK----DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178 +P D N L+ W+AME+L G K++G+SNFS I LL G + Sbjct: 144 YPPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLR--GAEI 201 Query: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD----RPWAKPEDPSLLEDPKI 234 KP Q+E HPYL Q +LI+Y S+GI +TAYS G + + P+L E I Sbjct: 202 KPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKTI 261 Query: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294 IA K+KKT AQVL+R+ QR++ +IPKS P R+++N++V DF LS E+ I ++ Sbjct: 262 TSIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLDQ 321 Query: 295 NWRACN 300 + R N Sbjct: 322 DLRFNN 327 >1K8C-A nrPDB Length = 322 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 120/316 (37%), Positives = 168/316 (53%), Gaps = 12/316 (3%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 ++LS+ MP +G G WK E V AI AGYR D A Y NE EVG+ ++ I Sbjct: 8 IKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAID 67 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--SGDDL 122 E VKRE++F+ SKLW + + V A KTL DLK+ Y+D++LIH+P FK ++ Sbjct: 68 EGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEK 127 Query: 123 FPK----DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178 +P D N + L+ W+A+E+LV G +K++GVSNF + LL G Sbjct: 128 YPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLR--GATI 185 Query: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD----RPWAKPEDPSLLEDPKI 234 KP QVE HPYL Q KLI++ G+T+TAYS G P+L I Sbjct: 186 KPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTI 245 Query: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294 K IAAK+ KT A+VL+R+ QR + VIPKS P R+V+N F L+ E+ I + Sbjct: 246 KAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIAKLDI 305 Query: 295 NWRACNVLQSSHLEDY 310 R + ++ + Sbjct: 306 GLRFNDPWDWDNIPIF 321 >5Z6T-A nrPDB Length = 343 Score = 377 bits (968), Expect = e-105, Method: Composition-based stats. Identities = 119/318 (37%), Positives = 168/318 (52%), Gaps = 12/318 (3%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 ++L++ MP VG G WK + E + AI GYR D A Y NE VG +++ Sbjct: 27 PSIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKA 86 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--SGD 120 I E VKREDLF+ SKLW + V KA +TL DL++ Y+D++LIH+P FK + Sbjct: 87 IDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLE 146 Query: 121 DLFPK----DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGL 176 + +P N L+ W+A+E+LV G ++++GVSNF + LL G Sbjct: 147 EKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLR--GA 204 Query: 177 KYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPD----RPWAKPEDPSLLEDP 232 KP QVE HPYL Q +LI++ S+GI VTAYS G L E+ Sbjct: 205 TIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENE 264 Query: 233 KIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSF 292 IK IAAKH K+ AQVL+R+ QR + +IPKS T R++EN V F L +++ A I Sbjct: 265 TIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKL 324 Query: 293 NRNWRACNVLQSSHLEDY 310 + N R + + + Sbjct: 325 DINLRFNDPWDWDKIPIF 342 >3H7R-A nrPDB Length = 331 Score = 376 bits (966), Expect = e-105, Method: Composition-based stats. Identities = 128/309 (41%), Positives = 181/309 (58%), Gaps = 16/309 (5%) Query: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 F EL+T AK+P VGLGT+ V A++ AI GYRHIDCA +Y NE E+G +++ I Sbjct: 27 FFELNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLI 82 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 + VKRE+LFI SKLW V KA EKTL+DL++ Y+D+YLIHWP K + L Sbjct: 83 GDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLM 141 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 P + + K W+AME L D G +A+GVSNFS ++ LLN + P N Sbjct: 142 PTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVN 195 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 QVECHP Q+ L + C SKG+ ++ YSPLGS + + +L++P + E+A K K Sbjct: 196 QVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRL---KVLQNPIVTEVAEKLGK 252 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQ 303 T AQV +R+ +Q V+PKS + AR+ EN+ VFD+ + E++ T S + C + Sbjct: 253 TTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIP-EDLFTKFSNIPQEKFCRATE 311 Query: 304 SSHLEDYPF 312 + E + F Sbjct: 312 FA-HETHGF 319 >4GIE-A nrPDB Length = 290 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 117/296 (39%), Positives = 168/296 (56%), Gaps = 34/296 (11%) Query: 4 FVELSTKAKMPIVGLGTWKSPLG-KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 V L +MP +GLG W++ G + AV+ AI+AGYRHID AY+Y NE VG+ I+E Sbjct: 15 CVTLHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVGQGIRES 74 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 V RE++++ +K+W + AFE++ + L L Y+D+YLIHWP Sbjct: 75 ----GVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWP--------- 121 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 GK F+D W+A+E+L +E V+A+GVSNF + +L K +P+ Sbjct: 122 -----------GKKKFVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFK--SCKIRPMV 168 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 NQVE HP Q L ++C I +TA+SPLGS E+ +L++ + EIA KH Sbjct: 169 NQVELHPLFQQRTLREFCKQHNIAITAWSPLGSG-------EEAGILKNHVLGEIAKKHN 221 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298 K+ AQV+IR+ IQ ++ IPKS RI EN V+DFKL++EEM I N + R Sbjct: 222 KSPAQVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRI 277 >4F40-A nrPDB Length = 288 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 127/297 (42%), Positives = 170/297 (57%), Gaps = 29/297 (9%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKE-AVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 V LS KMP GLG W+SP G+V E AVK A+ AGYRHID A +Y+NE VG ++ Sbjct: 11 AMVTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA 70 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 V RED+FI +KLW T AFE++ + L + Y+D+YLIHWP G D Sbjct: 71 S----GVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP----RGKD 122 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 + K+ K +LD+W A E+L E V+A+GVSNF +E +L P+ Sbjct: 123 ILSKEGK--------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAM--CTVTPM 172 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 NQVE HP Q L +C +K I V A+SPLG LL +P + I AK+ Sbjct: 173 VNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGK----------LLSNPILSAIGAKY 222 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298 KTAAQV++R++IQ+N+I IPKSV RI EN +FDF+L E++ +I + N N R Sbjct: 223 NKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSRY 279 >1VBJ-A nrPDB Length = 281 Score = 359 bits (921), Expect = e-100, Method: Composition-based stats. Identities = 123/299 (41%), Positives = 165/299 (55%), Gaps = 37/299 (12%) Query: 1 MATFVELSTKAKMPIVGLGTWKSPLG-KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAI 59 + ++LS MP++G G WK G + + A AI +GYRHID A +Y+NE G AI Sbjct: 8 LTQSLKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRAI 67 Query: 60 QEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSG 119 V RE+LF+ +KLW + AFEK++K L L Y+D+YLIHWP Sbjct: 68 ASC----GVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWP------ 117 Query: 120 DDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYK 179 GK F+D W+A E+L + V+A+GVSNF IE+LL K Sbjct: 118 --------------GKDKFIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKH--CKVA 161 Query: 180 PVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAA 239 P+ NQ+E HP L Q+ L +YC SK I VTA+SPLG L+ED ++K I Sbjct: 162 PMVNQIELHPLLNQKALCEYCKSKNIAVTAWSPLGQG----------HLVEDARLKAIGG 211 Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298 K+ KTAAQV++R+ IQ VI IPKS ARI EN +FDF+L+ E++ I N R Sbjct: 212 KYGKTAAQVMLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHRY 270 >3KRB-A nrPDB Length = 334 Score = 354 bits (908), Expect = 3e-98, Method: Composition-based stats. Identities = 124/310 (40%), Positives = 178/310 (57%), Gaps = 15/310 (4%) Query: 14 PIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE--KAVKRE 71 P +G GTW++P V+ AV+ A+ GYRHIDCAYVYQNE +G A + ++ +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 72 DLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD--DLFPKDDKG 129 D++I SKLW LVR+ +KT+ DL++ YLD++L+HWP F D DLFPKD +G Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 130 NAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHP 189 A+ K D W AME+LV+EGLVK +GVSN++ + LLN K KP+ NQ+E HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYA--KIKPLVNQIEIHP 203 Query: 190 YLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP---SLLEDPKIKEIAAKHKKTAA 246 + + +++C GI VTAYSP+G P +LE +K IA + Sbjct: 204 WHPNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPH 263 Query: 247 QVLIRFHIQR----NVIVIPKSVTPARIVENIQVFDFKLSDEEMATIL--SFNRNWRACN 300 V + +H+++ VIPKS TPARI N + + +LSD++M I N+ R C+ Sbjct: 264 CVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIRFCD 323 Query: 301 VLQSSHLEDY 310 + + Sbjct: 324 PAIFWKVPLF 333 >1QWK-A nrPDB Length = 317 Score = 353 bits (907), Expect = 4e-98, Method: Composition-based stats. Identities = 120/324 (37%), Positives = 170/324 (52%), Gaps = 23/324 (7%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 ++LS +MP++GLGTW+S +V AVK A+ AGYR ID A VYQNE +G AI+E Sbjct: 5 TASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKE 64 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 ++E VKRE+LFI +K W + ++LK L+L Y+D+YL H P F Sbjct: 65 LLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAF----- 119 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 DD I D W + + GL KA+GVSN+++ QI + L L PV Sbjct: 120 ---NDDMSEHIASPVE--DVWRQFDAVYKAGLAKAVGVSNWNNDQISRALA---LGLTPV 171 Query: 182 TN-QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPED---------PSLLED 231 N QVE H Y Q + +C I+VT+Y+ LGSP R PS L+D Sbjct: 172 HNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQD 231 Query: 232 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILS 291 + +A K KT AQVL+R+ + R ++PKS+ RI EN +VFDF L++E++A + Sbjct: 232 QNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEE 291 Query: 292 FNRNWRACNVLQSSHLEDYPFNAE 315 + R + + F AE Sbjct: 292 SKNSQRLFLQDFMTGHPEDAFAAE 315 >1VP5-A nrPDB Length = 298 Score = 351 bits (901), Expect = 2e-97, Method: Composition-based stats. Identities = 105/295 (35%), Positives = 162/295 (54%), Gaps = 31/295 (10%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64 V L+ +MPI+G G ++ P K +E V AI GYR ID A Y NE VG AI+ I Sbjct: 18 VTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAID 77 Query: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124 E V+RE+LF+ +KLW + +KAFEK+LK L+L Y+D+YLIH P G Sbjct: 78 EGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG--------- 128 Query: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184 AW+AMEE+ +GLV+A+GVSNF ++ L+ + P NQ Sbjct: 129 ------------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHH--EIVPAVNQ 174 Query: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244 +E HP+ +++ I++ + I A+ P + ++ ++ ++ IA K+ KT Sbjct: 175 IEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRK--------NIFQNGVLRSIAEKYGKT 226 Query: 245 AAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299 AQV++R+ Q+ ++ IPK+V R+ ENI +FDF+L+ E+M I + + A Sbjct: 227 VAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQSAF 281 >2BGQ-A nrPDB Length = 344 Score = 346 bits (889), Expect = 6e-96, Method: Composition-based stats. Identities = 115/297 (38%), Positives = 166/297 (55%), Gaps = 17/297 (5%) Query: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAI-DAGYRHIDCAYVYQNEHEVGEAIQEKI 63 L + MP VGLGTW++ +V+ AI +AGYRH+D A Y E EVG+ ++ + Sbjct: 40 FVLKSGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAM 98 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 E + R+DLF+ SK+W T VR A E TLKDL+L Y+D+Y IHWP K G + Sbjct: 99 -EAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMP 157 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 P + G + + W+ ME LV +GLVK +GV N++ ++ +LL K P Sbjct: 158 P--EAGEVL--EFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSA--KIPPAVC 211 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 Q+E HP +K+ + C GI +TAYSPLGS ++ +L DP ++++A K K Sbjct: 212 QMEMHPGWKNDKIFEACKKHGIHITAYSPLGSSEK--------NLAHDPVVEKVANKLNK 263 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300 T QVLI++ +QR VIPKS RI ENIQVF +++ +E+ + S R Sbjct: 264 TPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLT 320 >1MZR-A nrPDB Length = 296 Score = 340 bits (873), Expect = 4e-94, Method: Composition-based stats. Identities = 104/295 (35%), Positives = 168/295 (56%), Gaps = 34/295 (11%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 T ++L MP +GLG W++ +V A++ A++ GYR ID A Y+NE VG+A++ Sbjct: 26 TVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA 85 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 +V RE+LFI +KLW +RP R+A +LK L+L Y+D+YL+HWP Sbjct: 86 ----SVNREELFITTKLWNDDHKRP--REALLDSLKKLQLDYIDLYLMHWPVP------- 132 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 +++AW+ M EL EGL+K++GV NF +++L+++ G PV Sbjct: 133 -----------AIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETG--VTPVI 179 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 NQ+E HP + Q +L + + I ++SPL + + + I+++A K+ Sbjct: 180 NQIELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKG--------VFDQKVIRDLADKYG 231 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297 KT AQ++IR+H+ ++VIPKSVTP+RI EN V+DF+L +E+ I ++ R Sbjct: 232 KTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKR 286 >4MHB-A nrPDB Length = 297 Score = 325 bits (834), Expect = 1e-89, Method: Composition-based stats. Identities = 95/290 (32%), Positives = 148/290 (51%), Gaps = 36/290 (12%) Query: 5 VELSTKAKMPIVGLGTWKSPL-GKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 V+L+ MP++G G ++ + + AV AI+ GYR ID A YQNE +VG A++ Sbjct: 18 VKLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNALK--- 74 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 + R++LFI +KLW + FE++L L+L Y+D+YLIH P G G Sbjct: 75 -LSGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPYGDVHG---- 129 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 AW AMEEL G ++A+GVSNF ++ L+ K P N Sbjct: 130 -----------------AWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFN--KIIPAVN 170 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 Q+E +P+ Q + + S+GI A++P L ++P + I K+ K Sbjct: 171 QIEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRNG--------LFQNPVLTAIGEKYGK 222 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFN 293 + QV++R+ QR ++ + KSV R+ ENI + DF+LS E+M I + + Sbjct: 223 SVGQVVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALD 272 >3D3F-A nrPDB Length = 275 Score = 324 bits (832), Expect = 2e-89, Method: Composition-based stats. Identities = 120/295 (40%), Positives = 168/295 (56%), Gaps = 37/295 (12%) Query: 5 VELSTKAKMPIVGLGTWKSPLG-KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 V+L +MP GLG +K G + E+VK AI GYR ID A +Y+NE VG I+E Sbjct: 8 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKES- 66 Query: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF 123 V RE+LFI SK+W AFEK+L+ L+L YLD+YLIHWP Sbjct: 67 ---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 113 Query: 124 PKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTN 183 GK + D W A+E+L +G ++A+GVSNF +E+LL + KP+ N Sbjct: 114 ----------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDA--EIKPMVN 161 Query: 184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKK 243 QVE HP LTQ++L YC +GI + A+SPL LL++ + +IA KH K Sbjct: 162 QVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQGQ----------LLDNEVLTQIAEKHNK 211 Query: 244 TAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298 + AQV++R+ +Q V+ IPKS+ RI+EN +FDF+LS E+M I + N++ R Sbjct: 212 SVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERV 266 >4IJC-A nrPDB Length = 344 Score = 320 bits (820), Expect = 5e-88, Method: Composition-based stats. Identities = 114/323 (35%), Positives = 185/323 (57%), Gaps = 30/323 (9%) Query: 4 FVELSTKAKMPIVGLGTWK--SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 + L+ ++P +GLGT L + K+AVK AI AGYRHID A+ Y+ E VGEAI+E Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 +++ ++KREDLFI +K+WP ++ V ++ ++LK L L Y+D+ L HWP F+ D Sbjct: 84 LLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 Query: 122 L--------FPKDDKGNAIG-GKATFLDAWEAMEELV---DEGLVKALGVSNFSHFQIEK 169 P DD G + +L+ ++ +E++ ++ V+A+GVSNFS +E+ Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 Query: 170 LLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLL 229 L+ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P L Sbjct: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------L 251 Query: 230 EDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI 289 + P +K++A K+ T +LI +HI++ IVIP+S+ P RI +I+ L+ +E+ + Sbjct: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFA--SLTKDELQEL 309 Query: 290 LSFNRNW--RACNVLQSSHLEDY 310 F + R + ++ L ++ Sbjct: 310 NDFGEKYPVRFIDEPFAAILPEF 332 >4OTK-A nrPDB Length = 318 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 96/297 (32%), Positives = 144/297 (48%), Gaps = 34/297 (11%) Query: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61 A + L+ + MP++GLG + + + AV A++ G R ID AY Y NE VG AI Sbjct: 46 APSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAI-- 103 Query: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121 V RE+LF+ +KL ++A +L L L Y+D+YLIHWP Sbjct: 104 --AASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPAPPV---- 157 Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181 ++DAW M + EG +++GVSNF+ IE L++ P Sbjct: 158 --------------GKYVDAWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTF--VTPA 201 Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKH 241 NQ+E HP L Q++L + + +Y PL LL++P + IA+++ Sbjct: 202 VNQIELHPLLNQDELRKANAQHTVVTQSYCPLALGR----------LLDNPTVTSIASEY 251 Query: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA 298 KT AQVL+R+++Q V+ +S P RI N VFDF+L+ E M + N R Sbjct: 252 VKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRV 308 >1A80-A nrPDB Length = 277 Score = 309 bits (793), Expect = 6e-85, Method: Composition-based stats. Identities = 93/307 (30%), Positives = 144/307 (46%), Gaps = 35/307 (11%) Query: 3 TFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62 + L+ +P +G G +K P + AV+ A++ GYRHID A +Y NE V Sbjct: 3 PSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGV----GAA 58 Query: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122 I + R+DLFI +KLW + A ++L L L +D+YL+HWP Sbjct: 59 IAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTP------- 111 Query: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182 ++ AWE M EL GL +++GVSN +E+++ G P Sbjct: 112 -----------AADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATG--VVPAV 158 Query: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 NQ+E HP Q ++ + + + + ++ PLG L + AA H Sbjct: 159 NQIELHPAYQQREITDWAAAHDVKIESWGPLGQGKY--------DLFGAEPVTAAAAAHG 210 Query: 243 KTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVL 302 KT AQ ++R+H+Q+ +V PKSV R+ EN+ VFDF L+D E+A I + + Sbjct: 211 KTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMDPG---DGSG 267 Query: 303 QSSHLED 309 + S D Sbjct: 268 RVSAHPD 274 >3UP8-A nrPDB Length = 298 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 96/295 (32%), Positives = 154/295 (52%), Gaps = 37/295 (12%) Query: 8 STKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKA 67 S A +P +G GT++ +V + A+ G+RH+D A +Y NE EVGEAIQ+ Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQKS----G 84 Query: 68 VKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDD 127 + R D+F+ +K+W + + +++L+ L+ ++D+ L+HWP Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWP-------------- 130 Query: 128 KGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVEC 187 G + A+ E+ + G V+ +G+SNF+ Q+E+ TNQVE Sbjct: 131 -----GSDVPMAERIGALNEVRNAGKVRHIGISNFNTTQMEEAARLSDAPI--ATNQVEY 183 Query: 188 HPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQ 247 HPYL Q K++Q G+++T+Y + + P DP + EI +H KTAAQ Sbjct: 184 HPYLDQTKVLQTARRLGMSLTSYYAMANGKVP----------ADPLLTEIGGRHGKTAAQ 233 Query: 248 VLIRFHI-QRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR-NWRACN 300 V +R+ + Q++VIV+ K+ T AR+ EN +FDF L+ EEMA + R N R N Sbjct: 234 VALRWLVQQQDVIVLSKTATEARLKENFAIFDFALTREEMAAVRELARPNGRIVN 288 >4H8N-A nrPDB Length = 310 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 98/306 (32%), Positives = 155/306 (50%), Gaps = 37/306 (12%) Query: 3 TFVELSTKAKMPIVGLGT-WKSPLG------KVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55 TF S K +G GT WK ++ + + + + G+RHID A Y + EV Sbjct: 13 TFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEV 72 Query: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKA----FEKTLKDLKLSYLDVYLIH 111 GEA++ V RED+++ +K P + K+ +K L L + Y+D++LIH Sbjct: 73 GEALKRT----DVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLIH 128 Query: 112 WPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLL 171 P + T AWEA+ E G V+ +G+SN + +EKL Sbjct: 129 SPFFTTEQTHGY-------------TLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLF 175 Query: 172 N-KPGLKYKPVTNQVECHPYLTQE--KLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228 P +Y PV NQ+E HP+L + ++++C GI V A+SPL P A+ E +L Sbjct: 176 AASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA----PLARVETNAL 231 Query: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288 E +K +A K+KKT AQVL+R+ +QR ++ + S +R+ E++ +FDF+L+DEE+ Sbjct: 232 AE--TLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNE 289 Query: 289 ILSFNR 294 I Sbjct: 290 INKIGD 295 >3WG6-A nrPDB Length = 307 Score = 264 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 80/307 (26%), Positives = 142/307 (46%), Gaps = 42/307 (13%) Query: 5 VELSTKAKMPIVGLGTWKSP--------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVG 56 +LS K+P V GT ++ +++A+ +G+RHID A +Y E+G Sbjct: 11 FKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIG 70 Query: 57 EAIQEKIQEKAVKREDLFIVSKLWPTFFERP-------LVRKAFEKTLKDLKLSYLDVYL 109 A++ + R+D+FI K A + L+DL L Y+D+YL Sbjct: 71 IALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYL 126 Query: 110 IHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEK 169 IH+P + ++AW +E +EGL + +GVSNF+ ++ Sbjct: 127 IHFPYISEK--------------SHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKS 172 Query: 170 LLNKPGLKYKPVTNQVECHPYLTQEK--LIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227 +L+ PV NQ+E YL + +++Y +GI + AY PLG + P Sbjct: 173 ILD-ANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGPL--- 228 Query: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287 D + +++ K+K+ Q+L+R+ +QR ++ I + RI + +++FDF+L E+ Sbjct: 229 ---DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDED 285 Query: 288 TILSFNR 294 I + Sbjct: 286 QITKVGK 292 >1PYF-A nrPDB Length = 312 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 78/322 (24%), Positives = 131/322 (40%), Gaps = 74/322 (22%) Query: 16 VGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQ---NEHEVGEAIQEKI 63 +GLGT KE V+ AI G +D AY+Y +E +GE ++E Sbjct: 16 IGLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLRE-- 73 Query: 64 QEKAVKREDLFIVSKLWPTFFE--------RPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 RED+ I +K ++K+ +++LK L Y+D++ IH+P Sbjct: 74 ----FNREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP-- 127 Query: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 D+ PKD+ A A+ E+ G ++++GVSNFS Q+++ NK G Sbjct: 128 ----DEHTPKDE-------------AVNALNEMKKAGKIRSIGVSNFSLEQLKE-ANKDG 169 Query: 176 LKYKPVTNQVECHPYL--TQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDP- 232 L Q E + ++ Y I+ Y PL S ED + E Sbjct: 170 LVD---VLQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVSGLLAGKYTEDTTFPEGDL 226 Query: 233 --------------------KIKEIAAKHKKTAAQVLIRFHIQRNV--IVIPKSVTPARI 270 K+ IA KH +++ +++ R I+IP + ++ Sbjct: 227 RNEQEHFKGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDILIPGAKRADQL 286 Query: 271 VENIQVFDFKLSDEEMATILSF 292 ++NI+ D LS E+++ I Sbjct: 287 IDNIKTADVTLSQEDISFIDKL 308 >3N6Q-A nrPDB Length = 346 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 65/334 (19%), Positives = 133/334 (39%), Gaps = 75/334 (22%) Query: 9 TKAKMPIVGLGTWKS-----PLGKVKEAVKVAIDAGYRHIDCAYVYQ-----NEHEVGEA 58 + ++P + LG W + L + ++ A D G H D A Y E G Sbjct: 21 SGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL 80 Query: 59 IQEKIQEKAVKREDLFIVSK----LWPTFFERPLVRK----AFEKTLKDLKLSYLDVYLI 110 ++E R++L I +K +WP + RK + +++LK + L Y+D++ Sbjct: 81 LREDFAA---YRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYS 137 Query: 111 HWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKL 170 H D+ P ++ + A+ V G +G+S++S + +K+ Sbjct: 138 H------RVDENTPMEETAS-------------ALAHAVQSGKALYVGISSYSPERTQKM 178 Query: 171 LNK------PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL----------- 213 + P L ++P N + ++ + L+ + G+ A++PL Sbjct: 179 VELLREWKIPLLIHQPSYNL--LNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLN 236 Query: 214 GSPDRPWAKPE-------DPSLLEDPK------IKEIAAKHKKTAAQVLIRFHIQ--RNV 258 G P E P +L + + E+A + ++ AQ+ + + ++ R Sbjct: 237 GIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVT 296 Query: 259 IVIPKSVTPARIVENIQ-VFDFKLSDEEMATILS 291 V+ + ++ EN+Q + + S +E+A I Sbjct: 297 SVLIGASRAEQLEENVQALNNLTFSTKELAQIDQ 330 >1PZ1-A nrPDB Length = 333 Score = 180 bits (457), Expect = 7e-46, Method: Composition-based stats. Identities = 72/331 (21%), Positives = 125/331 (37%), Gaps = 71/331 (21%) Query: 9 TKAKMPIVGLGTWK--------SPLGKVKEAVKVAIDAGYRHIDCAYVY---QNEHEVGE 57 T + +GLGTW + E ++ A+D G ID A Y Q+E VG+ Sbjct: 9 TGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGK 68 Query: 58 AIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKA--------FEKTLKDLKLSYLDVYL 109 AI+E + KR+ + + +K + L R A E +LK L+ Y+D+Y Sbjct: 69 AIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLYQ 123 Query: 110 IHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEK 169 +HWP + E M+EL D G ++A+GVSNFS Q++ Sbjct: 124 VHWPDPL-------------------VPIEETAEVMKELYDAGKIRAIGVSNFSIEQMDT 164 Query: 170 LLNK-PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228 P +P N E +E ++ Y IT Y L E+ + Sbjct: 165 FRAVAPLHTIQPPYNLFE---REMEESVLPYAKDNKITTLLYGSLCRGLLTGKMTEEYTF 221 Query: 229 LEDPK---------------------IKEIAA-KHKKTAAQVLIRFHIQRNVIVIP--KS 264 D + ++A ++ K+ + +R+ + + I + Sbjct: 222 EGDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADIALWGA 281 Query: 265 VTPARIVENIQVFDFKLSDEEMATILSFNRN 295 P ++ ++ + L+ E+ I + N Sbjct: 282 RKPGQLEALSEITGWTLNSEDQKDINTILEN 312 >4R9O-A nrPDB Length = 301 Score = 164 bits (416), Expect = 4e-41, Method: Composition-based stats. Identities = 65/292 (22%), Positives = 108/292 (36%), Gaps = 43/292 (14%) Query: 18 LGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVS 77 L W ++ ++ +D G +D A +Y ++ A E + RE L IV+ Sbjct: 27 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGG-YQCEAAFGEALTLAPHLREKLQIVT 85 Query: 78 K------------LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125 K L +R + + E++LK+L YLD+ LIH P DD+ Sbjct: 86 KCGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPDPLMDADDVA-- 143 Query: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185 EA + L G V+ GVSNF+ Q L ++ L + TNQV Sbjct: 144 -----------------EAFQHLHQSGKVRHFGVSNFTPAQFTLLQSR--LPFTLATNQV 184 Query: 186 ECHPYLT---QEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 E P + + I A+S LG + P E + IA + Sbjct: 185 EISPVHQPLLLDGTLDQLQQLRIRPMAWSCLGGGRLFNDEAYQPLRQE---LSVIAQELN 241 Query: 243 -KTAAQVLIRFHIQRNVIVIP--KSVTPARIVENIQVFDFKLSDEEMATILS 291 + QV+ + ++ +P S R+ ++ L+ ++ I Sbjct: 242 ASSIEQVVYAWILRLPSQPLPIIGSGKIERVRAALEAETLSLTRQQWFRIRK 293 >1OG6-A nrPDB Length = 298 Score = 157 bits (396), Expect = 8e-39, Method: Composition-based stats. Identities = 59/292 (20%), Positives = 109/292 (37%), Gaps = 43/292 (14%) Query: 18 LGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVS 77 L W ++ ++ +D G +D A +Y ++ A E ++ RE + IVS Sbjct: 24 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGG-YQCEAAFGEALKLAPHLRERMEIVS 82 Query: 78 K------------LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125 K + +R + K+ E++L +L +LD+ LIH P D++ Sbjct: 83 KCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVA-- 140 Query: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185 +A + L G V+ GVSNF+ Q L ++ L + TNQV Sbjct: 141 -----------------DAFKHLHQSGKVRHFGVSNFTPAQFALLQSR--LPFTLATNQV 181 Query: 186 ECHPYLT---QEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 E P + + + A+S LG P E + +A + Sbjct: 182 EISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLFNDDYFQPLRDE---LAVVAEELN 238 Query: 243 K-TAAQVLIRFHIQRNVIVIP--KSVTPARIVENIQVFDFKLSDEEMATILS 291 + QV+ + ++ +P S R+ ++ K++ ++ I Sbjct: 239 AGSIEQVVNAWVLRLPSQPLPIIGSGKIERVRAAVEAETLKMTRQQWFRIRK 290 >1LQA-A nrPDB Length = 346 Score = 157 bits (396), Expect = 9e-39, Method: Composition-based stats. Identities = 73/346 (21%), Positives = 131/346 (37%), Gaps = 72/346 (20%) Query: 11 AKMP-------IVGLGTW----KSPLGKVKEAVKVAIDAGYRHIDCAYVYQ--------- 50 ++P +GLGT ++ + A+ G ID A +Y Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 51 -NEHEVGEAIQEKIQEKAVKREDLFIVSKLW------------PTFFERPLVRKAFEKTL 97 E VG + + RE L I SK+ +R +R+A +L Sbjct: 64 LTETYVGNWLAKH-----GSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118 Query: 98 KDLKLSYLDVYLIHWPQGFKS--GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVK 155 K L+ YLD+Y +HWPQ + G + D A + LD +A+ E G ++ Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPA----VSLLDTLDALAEYQRAGKIR 174 Query: 156 ALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK-----LIQYCHSKGITVTAY 210 +GVSN + F + + L+ P ++ +PY + L + +G+ + AY Sbjct: 175 YIGVSNETAFGVMRYLHLADKHDLPRIVTIQ-NPYSLLNRSFEVGLAEVSQYEGVELLAY 233 Query: 211 SPLGSPDRPWAKPED-------PSLLE-------DPKIKE------IAAKHKKTAAQVLI 250 S LG +L + K IA +H AQ+ + Sbjct: 234 SCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMAL 293 Query: 251 RFHIQRNVI--VIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294 F ++ + + + T ++ NI+ +LS++ +A I + ++ Sbjct: 294 AFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQ 339 >3EB3-A nrPDB Length = 327 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 65/330 (19%), Positives = 122/330 (36%), Gaps = 66/330 (20%) Query: 9 TKAKMPIVGLGTW-----KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63 + ++ +GLGTW + + + +A D G D A VY + I Sbjct: 11 SGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKA-EVVLGNII 69 Query: 64 QEKAVKREDLFIVSKLWPTF-------FERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 116 ++K +R L I +K++ R + + + +L+ L+L Y+DV + P Sbjct: 70 KKKGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--- 126 Query: 117 KSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKL--LNKP 174 D P ++ AM ++++G+ G S +S +I + + + Sbjct: 127 ---DPNTPMEE-------------TVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQ 170 Query: 175 GLKYKPVTNQVECHPYLTQE---KLIQYCHSKGITVTAYSPL-----------GSPDRPW 220 P+ Q E H + ++ +L + H G+ +SPL G P Sbjct: 171 FNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSR 230 Query: 221 AKPEDPSLLEDPKIK--------------EIAAKHKKTAAQVLIRFHIQ-RNV-IVIPKS 264 A + L+D + IA + T Q+ I + ++ V V+ + Sbjct: 231 ASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGA 290 Query: 265 VTPARIVENIQVFDF--KLSDEEMATILSF 292 +++ENI KLS + I S Sbjct: 291 SNAEQLMENIGAIQVLPKLSSSIVHEIDSI 320 >2BP1-A nrPDB Length = 360 Score = 77.7 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 57/313 (18%), Positives = 109/313 (34%), Gaps = 75/313 (23%) Query: 36 IDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRE-DLFIVSKL--WPTF-FERPLVRK 91 ++ G+ +D A++Y + E I + + + I +K W + VR Sbjct: 65 LERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 122 Query: 92 AFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDE 151 E +LK L+ +D++ +H P D P ++ A + L E Sbjct: 123 QLETSLKRLQCPQVDLFYLHAP------DHGTPVEE-------------TLHACQRLHQE 163 Query: 152 GLVKALGVSNFSHFQIEKL--LNKPGLKYKPVTNQVECHPYLTQ--EKLIQYCHSKGITV 207 G LG+SN++ +++ ++ L K P Q + Q +L G+ Sbjct: 164 GKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRF 223 Query: 208 TAYSPLGSP---------------------DRPWAKPEDPSLLEDPKIKEIA-------A 239 AY+PL WA+ ++ + IA A Sbjct: 224 YAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQA 283 Query: 240 KHKKTAAQV---LIRF-----HIQ--RNVIVIPKSVTPARIVENIQVFDFKLSDE---EM 286 + +A V +R+ +Q VI + ++ +N+ ++E E Sbjct: 284 AYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAA-----TEEGPLEP 338 Query: 287 ATILSFNRNWRAC 299 A + +FN+ W Sbjct: 339 AVVDAFNQAWHLV 351 >1GVE-A nrPDB Length = 327 Score = 75.4 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 56/322 (17%), Positives = 111/322 (34%), Gaps = 71/322 (22%) Query: 22 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQN--EHEVGEAIQEKIQEKAVKREDLFIVSKL 79 + + +V+ + G+ ID A+VY N + + + K + I +K Sbjct: 18 RMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCK---VKIATKA 74 Query: 80 WPTF---FERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKA 136 P F + VR E +LK L+ +D++ +H+P D P ++ Sbjct: 75 APMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFP------DHGTPIEE--------- 119 Query: 137 TFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKL--LNKPGLKYKPVTNQVECHPYLTQ- 193 +A +L EG LG+SN+ +++ ++ L K P Q + Q Sbjct: 120 ----TLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQV 175 Query: 194 -EKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDP-------------------- 232 +L G+ A++PL ++P Sbjct: 176 ETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKE 235 Query: 233 --------KIKEIAAKHKKTAAQV---LIRF---HIQ----RNVIVIPKSVTPARIVENI 274 K + + TA + +R+ H Q + VI + ++ +N+ Sbjct: 236 EHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNL 295 Query: 275 QVFDFKLSDEEMATILSFNRNW 296 + + E A + +F++ W Sbjct: 296 AL--VEEGPLEPAVVDAFDQAW 315 >2CLP-A nrPDB Length = 347 Score = 74.6 bits (182), Expect = 6e-14, Method: Composition-based stats. Identities = 53/324 (16%), Positives = 107/324 (33%), Gaps = 69/324 (21%) Query: 22 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRE-DLFIVSK-- 78 + + ++ G+ ID A+VY E I + + + + I +K Sbjct: 38 RMDAPTSAAVTRAFLERGHTEIDTAFVYS--EGQSETILGGLGLRLGGSDCRVKIDTKAI 95 Query: 79 -LWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137 L+ + +R E +LK L+ +D++ +H P D P ++ Sbjct: 96 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP------DHSTPVEE---------- 139 Query: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKL--LNKPGLKYKPVTNQVECHPYLTQ-- 193 A +L EG LG+SN++ +++ ++ L K P Q + Q Sbjct: 140 ---TLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 196 Query: 194 EKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDP--------------------- 232 +L G+ A++PL + + P Sbjct: 197 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEH 256 Query: 233 -------KIKEIAAKHKKTAAQV---LIRF-----HIQ--RNVIVIPKSVTPARIVENIQ 275 K + A + +A + +R+ +Q VI + ++ +N+ Sbjct: 257 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 316 Query: 276 VFDFKLSDEEMATILSFNRNWRAC 299 + E A + +FN+ W Sbjct: 317 AA--EEGPLEPAVVDAFNQAWHLV 338 >2C91-A nrPDB Length = 338 Score = 71.1 bits (173), Expect = 6e-13, Method: Composition-based stats. Identities = 60/336 (17%), Positives = 119/336 (35%), Gaps = 79/336 (23%) Query: 14 PIVGLGTW----KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVK 69 P LGT + +V+ ++ G+ +D A++Y + E I + Sbjct: 17 PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQS--ENILGGLGLGLGS 74 Query: 70 RE-DLFIVSKL--WPTF-FERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125 + + I +K W + +R E +LK L+ +D++ +H P D P Sbjct: 75 GDCTVKIATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAP------DHSTPV 128 Query: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKL--LNKPGLKYKPVTN 183 ++ A +L EG LG+SN++ +++ ++ L K P Sbjct: 129 EE-------------TLCACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVY 175 Query: 184 QVECHPYLTQ--EKLIQYCHSKGITVTAYSPLGSP---------------------DRPW 220 Q + Q +L+ G+ AY+PL W Sbjct: 176 QGMYNATTRQVEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNNW 235 Query: 221 AKPEDPSLLEDPKIKEIA--AK-----HKKTAAQV---LIRF-----HIQ--RNVIVIPK 263 A+ ++ + IA K + A ++ +R+ +Q R VI Sbjct: 236 AETYRNRFWKEHHFEAIALVEKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAVILG 295 Query: 264 SVTPARIVENIQVFDFKLSDE---EMATILSFNRNW 296 + ++ +N+ ++E E A + +F++ W Sbjct: 296 MSSLEQLEQNLAA-----TEEGPLEPAVVEAFDQAW 326 >4EXA-A nrPDB Length = 292 Score = 70.0 bits (170), Expect = 1e-12, Method: Composition-based stats. Identities = 53/281 (18%), Positives = 95/281 (33%), Gaps = 66/281 (23%) Query: 9 TKAKMPIVGLGTWK---------------SPLGKVKEAVKVAIDAGYRHIDCAYVYQ-NE 52 T + +GLGT K + + + +A D G ID A Y +E Sbjct: 38 TGLAVSPLGLGTVKFGRDQGVKYPSGFTIPDDREAADLLALARDLGINLIDTAPAYGRSE 97 Query: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLV--------RKAFEKTLKDLKLSY 104 +G ++ +RE IVSK+ F + V R++ E++LK L+ Sbjct: 98 ERLGPLLR-------GQREHWVIVSKVGEEFVDGQSVFDFSAAHTRRSVERSLKRLETDR 150 Query: 105 LDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSH 164 +++ L+H G+DL + + + L EGL+ A G+S + Sbjct: 151 IELVLVH-----SDGNDL-----------DILENSEVYPTLAALKREGLIGAYGLSGKTV 194 Query: 165 FQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE 224 + L + N E + +I+Y + + L S + Sbjct: 195 EGGLRALREGDCAMV-TYNLNER----AERPVIEYAAAHAKGILVKKALASGHACLGAGQ 249 Query: 225 DPS------LLEDP--------KIKEIAAKHKKTAAQVLIR 251 DP + + P I + H A ++ Sbjct: 250 DPVRASFELVFDQPGVAAAIVGTINPLHLAHNVAMAAQALK 290 >1JPH-A nrPDB Length = 388 Score = 31.9 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 4/57 (7%) Query: 15 IVGLGTWKSPLGKVKEAVKVAIDA-GYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70 +VGL W K +E V + G ++D +Y +E E+G+ +++ + + R Sbjct: 300 VVGL-DWTVAPKKARECVGKTVTLQG--NLDPCALYASEEEIGQLVKQMLDDFGPHR 353 >2WK1-A nrPDB Length = 282 Score = 31.9 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 46/144 (31%), Gaps = 19/144 (13%) Query: 10 KAKMP--IVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGE-AIQEKIQEK 66 +P +V G W+ + + A D R + A +Q +VGE + Sbjct: 103 GNNVPGDLVETGVWRGGACILMRGILRAHDVRDRTVWVADSFQGIPDVGEDGYAGDRKMA 162 Query: 67 AVKREDLFIVSKLWPTFFERPLVRKAFEK-TLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125 +R + VS VR+ F L D ++ +L P FK P Sbjct: 163 LHRRNSVLAVS--------EEEVRRNFRNYDLLDEQVRFL-------PGWFKDTLPTAPI 207 Query: 126 DDKGNAIGGKATFLDAWEAMEELV 149 D + W+ + L Sbjct: 208 DTLAVLRMDGDLYESTWDTLTNLY 231 >2WUA-A nrPDB Length = 440 Score = 30.7 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 205 ITVTAY-SPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQV 248 + V AY SPL R K P + P +K + K A+V Sbjct: 36 VIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEV 80 >1N7G-A nrPDB Length = 381 Score = 30.7 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 33/88 (37%), Gaps = 11/88 (12%) Query: 20 TWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKL 79 T V E K+A+ G D + Y E +G+ + ++R F ++ Sbjct: 16 TAPKADSTVVEPRKIALITGITGQDGS--YLTEFLLGKGYE---VHGLIRRSSNFNTQRI 70 Query: 80 WPTFFERPLVRKAFEKTLKDLKLSYLDV 107 + + V KA +KL Y D+ Sbjct: 71 NHIYIDPHNVNKAL------MKLHYADL 92 >5ZF1-A nrPDB Length = 301 Score = 30.7 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 14/23 (60%) Query: 187 CHPYLTQEKLIQYCHSKGITVTA 209 CH Y ++KL YC + I +TA Sbjct: 197 CHRYTPKDKLEAYCRNADIIITA 219 >4WO8-A nrPDB Length = 716 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 21/54 (38%), Gaps = 2/54 (3%) Query: 194 EKLIQYCHSKGITVTAYSP--LGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTA 245 K +++ + + + P LG+ R + P L P KEI KH Sbjct: 251 SKSLKFAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQP 304 >4EHI-A nrPDB Length = 534 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 40 YRHIDCAYVYQNEHEVGE 57 ++HID +VYQN EVGE Sbjct: 383 FKHIDGGFVYQNSDEVGE 400 >2PTS-A nrPDB Length = 462 Score = 29.2 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 39/108 (36%), Gaps = 16/108 (14%) Query: 97 LKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156 LKDL + Y D+ L+ G P + + ++ G + Sbjct: 154 LKDLAVQYRDIPLL----SRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKING 209 Query: 157 LGVSNFSHF----------QI-EKLLNKPGLKYKPVTNQVECHPYLTQ 193 V N++ Q E+ + G+++ P T Q+E H Y+ + Sbjct: 210 -AVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAE 256 >4L1C-A nrPDB Length = 103 Score = 28.8 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 18/37 (48%) Query: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178 W AM + V ++ +GVS Q++ + K GL Sbjct: 63 WSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPI 99 >6J2N-S nrPDB Length = 523 Score = 28.8 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 52 EHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLK---DLKLSYL 105 E+ V AI++ + E + ED FI + ++ ++ F++ +K L YL Sbjct: 420 EYMVSRAIRDGVIEAKINHEDGFIETTELLNIYDSEDPQQVFDERIKFANQLHDEYL 476 >3JCK-A nrPDB Length = 438 Score = 28.4 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 52 EHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLK---DLKLSYL 105 E+ V AI++ + E + ED FI + ++ ++ F++ +K L YL Sbjct: 335 EYMVSRAIRDGVIEAKINHEDGFIETTELLNIYDSEDPQQVFDERIKFANQLHDEYL 391 >5XOR-A nrPDB Length = 158 Score = 28.4 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 45/126 (35%), Gaps = 7/126 (5%) Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKAL-GVSNFSHFQIEKLLNKPGLKYK 179 + +D++ + D + EE +EG L G +NF Q + Y Sbjct: 22 NNPSEDERKKIRDLPISLFDYFIVGEEGNEEGRTPHLQGFANFVKKQTFNKVKW----YL 77 Query: 180 PVTNQVECHPYLTQEKLIQYCHSKG-ITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238 +E Q+ +YC +G + + +P R +LLE + +A Sbjct: 78 GARCHIEKAKGTDQQN-KEYCSKEGNLLIECGAPRSQGQRSDLSTAVSTLLESGSLVTVA 136 Query: 239 AKHKKT 244 +H T Sbjct: 137 EQHPVT 142 >3Q3N-A nrPDB Length = 500 Score = 28.0 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 15/29 (51%), Gaps = 3/29 (10%) Query: 84 FERPLVRKAFEKTLKDLKLS---YLDVYL 109 F + FE++L DL L Y D++L Sbjct: 293 FMYEWIIGQFERSLIDLGLDKPWYWDLFL 321 >2AXQ-A nrPDB Length = 467 Score = 28.0 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Query: 30 EAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLF--IVSKL-WPTFFER 86 E VK +D G D ++ EA+++ + K+ +EDL I SK W +R Sbjct: 273 EFVKALVDMGMLKDDANEIFSKPIAWNEALKQYLGAKSTSKEDLIASIDSKATWKDDEDR 332 Query: 87 PLVRKAF 93 + F Sbjct: 333 ERILSGF 339 >2ZVR-A nrPDB Length = 290 Score = 28.0 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 7/78 (8%) Query: 7 LSTKAKMPIVGLGTWKSPLGKVKEAV-------KVAIDAGYRHIDCAYVYQNEHEVGEAI 59 LS + +PI +GT ++ L K AI+ +H + A ++ +G Sbjct: 76 LSEELNLPICAIGTGQAYLADGLSLTHPNDEIRKKAIERVVKHTEVAGMFGALVIIGLVR 135 Query: 60 QEKIQEKAVKREDLFIVS 77 + + E+LFI S Sbjct: 136 GRREGRSYEETEELFIES 153 >4UEE-A nrPDB Length = 309 Score = 27.6 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 10/59 (16%) Query: 194 EKLIQYCHSKG-----ITVTAYS-----PLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 + ++ + G I++ +YS P G P ++ L + +A+ + Sbjct: 177 KSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYG 235 >5OM9-A nrPDB Length = 419 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 10/59 (16%) Query: 194 EKLIQYCHSKG-----ITVTAYS-----PLGSPDRPWAKPEDPSLLEDPKIKEIAAKHK 242 + ++ + G I++ +YS P G P ++ L + +A+ + Sbjct: 287 KSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYG 345 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.144 0.441 Lambda K H 0.267 0.0442 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,143,442 Number of Sequences: 36641 Number of extensions: 631910 Number of successful extensions: 2301 Number of sequences better than 10.0: 72 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1895 Number of HSP's gapped (non-prelim): 139 length of query: 316 length of database: 10,336,785 effective HSP length: 97 effective length of query: 219 effective length of database: 6,782,608 effective search space: 1485391152 effective search space used: 1485391152 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.2 bits)