BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O43745 (196 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2BEC-A nrPDB 398 e-112 2E30-A nrPDB 246 4e-66 5B8I-B nrPDB 116 5e-27 4ORC-B nrPDB 112 9e-26 4IL1-A nrPDB 112 1e-25 5A2H-A nrPDB 56 8e-09 2L1W-A nrPDB 55 1e-08 4OY4-A nrPDB 55 2e-08 1DGU-A nrPDB 55 3e-08 4E53-A nrPDB 54 3e-08 2N6A-A nrPDB 54 3e-08 2LM5-A nrPDB 54 3e-08 6O20-F nrPDB 54 3e-08 2F2P-A nrPDB 54 3e-08 1UHN-A nrPDB 54 4e-08 2ZFD-A nrPDB 54 4e-08 5I0I-E nrPDB 54 5e-08 3WFN-B nrPDB 54 6e-08 3EK4-A nrPDB 54 6e-08 3U0K-A nrPDB 52 2e-07 6HCS-A nrPDB 52 2e-07 2LCP-A nrPDB 51 3e-07 1CLM-A nrPDB 51 3e-07 1TOP-A nrPDB 50 4e-07 5ZOR-A nrPDB 50 5e-07 1GGZ-A nrPDB 49 2e-06 4I2Y-A nrPDB 49 2e-06 6EPA-A nrPDB 48 3e-06 5T7C-A nrPDB 47 4e-06 1JBA-A nrPDB 47 5e-06 3O4Y-A nrPDB 47 5e-06 2LAP-A nrPDB 47 6e-06 3DD4-A nrPDB 46 8e-06 3KF9-A nrPDB 46 1e-05 2KN2-A nrPDB 46 1e-05 2TN4-A nrPDB 46 1e-05 2L2E-A nrPDB 46 1e-05 5YPX-A nrPDB 45 1e-05 2JUL-A nrPDB 45 2e-05 2GGM-A nrPDB 45 2e-05 2NA0-A nrPDB 45 2e-05 2R2I-A nrPDB 45 2e-05 2ROB-A nrPDB 45 2e-05 2OBH-A nrPDB 44 3e-05 4ZCV-A nrPDB 44 3e-05 2I08-A nrPDB 44 3e-05 4N5X-A nrPDB 44 4e-05 2LMV-A nrPDB 44 4e-05 1TNP-A nrPDB 44 5e-05 1TRF-A nrPDB 44 6e-05 5M6C-E nrPDB 44 6e-05 5H7D-E nrPDB 44 6e-05 2E6W-A nrPDB 43 8e-05 3KHE-A nrPDB 43 9e-05 1V1G-A nrPDB 43 9e-05 5UKG-A nrPDB 42 1e-04 2RO9-A nrPDB 42 1e-04 3HZT-A nrPDB 42 1e-04 3K21-A nrPDB 42 1e-04 4JWQ-A nrPDB 42 1e-04 3J04-B nrPDB 42 2e-04 2K7C-A nrPDB 42 2e-04 2JU0-A nrPDB 42 2e-04 5COC-A nrPDB 42 2e-04 4Q57-A nrPDB 42 2e-04 5VLN-A nrPDB 42 2e-04 2K2I-A nrPDB 42 2e-04 1S1E-A nrPDB 41 3e-04 1M39-A nrPDB 41 3e-04 1S6C-A nrPDB 41 3e-04 5D43-A nrPDB 41 3e-04 6IIE-A nrPDB 41 3e-04 2RO8-A nrPDB 41 3e-04 3IFK-A nrPDB 41 3e-04 1BJF-A nrPDB 41 3e-04 2N7L-C nrPDB 41 3e-04 1DTL-A nrPDB 40 5e-04 2JNF-A nrPDB 40 6e-04 1FW4-A nrPDB 40 9e-04 5OTJ-D nrPDB 39 0.001 3NCG-A nrPDB 39 0.002 2KSZ-A nrPDB 39 0.002 2OPO-A nrPDB 39 0.002 2M97-A nrPDB 39 0.002 2LV7-A nrPDB 38 0.002 4GJF-A nrPDB 38 0.002 2LVK-A nrPDB 38 0.002 4RGJ-A nrPDB 38 0.003 2M29-A nrPDB 38 0.003 1JC2-A nrPDB 38 0.003 1H4B-A nrPDB 38 0.003 2M5E-A nrPDB 37 0.004 3L19-A nrPDB 37 0.004 2KZ2-A nrPDB 37 0.004 3Q5I-A nrPDB 37 0.004 5VE9-A nrPDB 37 0.005 3LIJ-A nrPDB 37 0.005 2I94-A nrPDB 37 0.005 4MVF-A nrPDB 37 0.005 2LHI-A nrPDB 37 0.006 4DS7-A nrPDB 37 0.007 2LHH-A nrPDB 37 0.008 3FWC-A nrPDB 37 0.008 1LKJ-A nrPDB 36 0.009 4YZB-A nrPDB 36 0.009 2AAO-A nrPDB 36 0.009 5JN2-A nrPDB 36 0.010 3QRX-A nrPDB 36 0.011 2D8N-A nrPDB 36 0.011 5B7X-A nrPDB 36 0.013 3PM8-A nrPDB 36 0.014 2LC5-A nrPDB 35 0.015 1ZMZ-A nrPDB 35 0.018 1F55-A nrPDB 35 0.018 2AMI-A nrPDB 35 0.019 1S6I-A nrPDB 35 0.030 2B1U-A nrPDB 34 0.033 3TZ1-A nrPDB 34 0.039 2VRG-A nrPDB 34 0.040 3LCP-C nrPDB 34 0.041 3A4U-B nrPDB 34 0.044 2GGZ-A nrPDB 34 0.049 4MSP-A nrPDB 34 0.051 1TIZ-A nrPDB 34 0.052 2BL0-C nrPDB 33 0.083 1JFJ-A nrPDB 33 0.083 2JNX-A nrPDB 33 0.085 4YGB-B nrPDB 33 0.11 2HF5-A nrPDB 33 0.11 2K2A-A nrPDB 32 0.15 5E37-A nrPDB 32 0.15 1C7W-A nrPDB 32 0.16 1OQP-A nrPDB 32 0.20 2I18-A nrPDB 32 0.21 5I2L-A nrPDB 32 0.24 5Z1Q-A nrPDB 31 0.27 4WPX-A nrPDB 31 0.30 3DTP-E nrPDB 31 0.30 2IM5-A nrPDB 31 0.35 2BL0-B nrPDB 30 0.51 2JOJ-A nrPDB 30 0.60 1QX2-A nrPDB 29 1.2 3I5H-B nrPDB 29 1.5 1ZFS-A nrPDB 28 1.7 2PMY-A nrPDB 28 2.0 4MN0-A nrPDB 28 2.3 5JOJ-A nrPDB 28 2.7 5JOL-A nrPDB 28 2.8 2L0P-A nrPDB 28 3.0 2ME6-A nrPDB 28 3.2 1QLS-A nrPDB 28 3.2 3AKA-A nrPDB 28 3.3 5VP3-A nrPDB 27 4.2 3JBH-C nrPDB 27 4.6 1CB1-A nrPDB 27 5.8 5XOP-A nrPDB 27 5.9 3PAT-A nrPDB 26 8.5 1RTP-1 nrPDB 26 8.8 1G33-A nrPDB 26 9.9 >2BEC-A nrPDB Length = 202 Score = 398 bits (1023), Expect = e-112, Method: Compositional matrix adjust. Identities = 196/196 (100%), Positives = 196/196 (100%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN Sbjct: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 Query: 61 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF Sbjct: 61 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 Query: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS Sbjct: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 Query: 181 LEKMDVEQKMSIRILK 196 LEKMDVEQKMSIRILK Sbjct: 181 LEKMDVEQKMSIRILK 196 >2E30-A nrPDB Length = 195 Score = 246 bits (629), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 119/195 (61%), Positives = 155/195 (79%), Gaps = 1/195 (0%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MGSR+S + + I++ETGFS + + RL+ RF +LD+ + G LSR D Q+I LA+N Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN 60 Query: 61 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 PLGDRII +FFP+G +V+F GF+R LAHFRP+ED + +++D PEPLNSR NKLH+AF Sbjct: 61 PLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNE-KSKDVNGPEPLNSRSNKLHFAF 119 Query: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 +LYDLD+D KISR E+LQVLR+MVGV +++EQL +IADRT+QEAD+DGD A+SF EF K Sbjct: 120 RLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKV 179 Query: 181 LEKMDVEQKMSIRIL 195 LEK+DVEQKMSIR L Sbjct: 180 LEKVDVEQKMSIRFL 194 >5B8I-B nrPDB Length = 171 Score = 116 bits (291), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 65/172 (37%), Positives = 94/172 (54%), Gaps = 16/172 (9%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDF 80 + F + RL RF LDR+K G + R + + ++ NPL R+I F DG VDF Sbjct: 13 SNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDF 72 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 FV L+ F ++ KL +AF++YD+DRDG IS E+ VL Sbjct: 73 QEFVSGLSAFSSK----------------GNKEEKLRFAFKVYDIDRDGFISNGELFIVL 116 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSI 192 ++MVG + + QL+ I D+T+ EAD DGDG +SF EFT+ +E DV M++ Sbjct: 117 KMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTL 168 >4ORC-B nrPDB Length = 170 Score = 112 bits (281), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 61/172 (35%), Positives = 94/172 (54%), Gaps = 16/172 (9%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 F + RL RF+ LD + G LS + + L NPL R+I+ F DG+ VDF Sbjct: 15 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ ++ F D + KL +AF++YD+D+DG IS E+ QVL++ Sbjct: 75 FIEGVSQFSVKGD----------------KEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 MVG + + QL+ I D+T+ AD+DGDG +SF EF + +D+ +KM + + Sbjct: 119 MVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 >4IL1-A nrPDB Length = 823 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 61/172 (35%), Positives = 94/172 (54%), Gaps = 16/172 (9%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 F + RL RF+ LD + G LS + + L NPL R+I+ F DG+ VDF Sbjct: 172 FDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 231 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ ++ F D + KL +AF++YD+D+DG IS E+ QVL++ Sbjct: 232 FIEGVSQFSVKGD----------------KEQKLRFAFRIYDMDKDGYISNGELFQVLKM 275 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 MVG + + QL+ I D+T+ AD+DGDG +SF EF + +D+ +KM + + Sbjct: 276 MVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 327 Score = 52.8 bits (125), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 81/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 65 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 108 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ +G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 109 VMT-NLGEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 146 >5A2H-A nrPDB Length = 149 Score = 56.2 bits (134), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 45/157 (28%), Positives = 81/157 (51%), Gaps = 27/157 (17%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNP----LGDRIIESFFPDGSQRVDFPGFV 84 F D++ G ++ +L + +L NP L D +I DG+ +DFP F+ Sbjct: 12 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEFL 70 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 ++A R ++D D+E + L AF+++D D++G IS E+ V+ + Sbjct: 71 NLMA--RKMKDTDSEEE--------------LKEAFRVFDKDQNGFISAAELRHVMT-NL 113 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 G ++T+E++ D ++EAD DGDG +++ EF K + Sbjct: 114 GEKLTDEEV----DEMIREADVDGDGQINYEEFVKVM 146 >2L1W-A nrPDB Length = 149 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 44/163 (26%), Positives = 84/163 (51%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGSQRV 78 S+ ++ F D++ G ++ +L I +L NP + + I DG+ + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 +F F+ ++A + V+D D E + L AF+++D D++G IS E+ Sbjct: 64 EFDEFLSLMA--KKVKDTDAEEE--------------LKEAFKVFDKDQNGYISASELRH 107 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + +G ++T+E++E + ++EAD DGDG V++ EF K + Sbjct: 108 VM-INLGEKLTDEEVEQM----IKEADLDGDGQVNYEEFVKMM 145 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 9/76 (11%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF- 177 AF L+D D DG I+ E+ V+R + TEE+L+++ + E D DG+G + F EF Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSL-DQNPTEEELQDM----ISEVDADGNGTIEFDEFL 69 Query: 178 ---TKSLEKMDVEQKM 190 K ++ D E+++ Sbjct: 70 SLMAKKVKDTDAEEEL 85 >4OY4-A nrPDB Length = 415 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 45/175 (25%), Positives = 85/175 (48%), Gaps = 25/175 (14%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG + Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTI 71 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 72 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 115 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIR 193 V+ +G ++T+E++ D ++EAD DGDG V++ EF + + +KM +R Sbjct: 116 VM-TNLGEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYVR 165 >1DGU-A nrPDB Length = 183 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 39/170 (22%), Positives = 80/170 (47%), Gaps = 29/170 (17%) Query: 21 TGFSQASLLRLHHRF--------RALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP 72 T ++ +L H RF R+++ + + + + + L NP +RI F Sbjct: 12 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 71 Query: 73 DGSQ-RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 ++ + F F+ +L+ F DT T D K HYAF+++D D DG + Sbjct: 72 SPAKDSLSFEDFLDLLSVF-----SDTATPDIKS-----------HYAFRIFDFDDDGTL 115 Query: 132 SRHEMLQVLRLMVG----VQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +R ++ +++ + G +++ +++ + D ++E+D D DG ++ EF Sbjct: 116 NREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 165 >4E53-A nrPDB Length = 185 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 83/164 (50%), Gaps = 27/164 (16%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNP----LGDRIIESFFPDGSQR 77 ++ + F D++ G ++ +L + +L NP L D +I DG+ Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 70 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 71 IDFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELR 114 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ +G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 115 HVM-TNLGEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 153 >2N6A-A nrPDB Length = 173 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 44/163 (26%), Positives = 83/163 (50%), Gaps = 27/163 (16%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNP----LGDRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP L D +I DG+ + Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTI 65 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 66 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 109 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ +G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 110 VM-TNLGEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 147 >2LM5-A nrPDB Length = 214 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 39/170 (22%), Positives = 80/170 (47%), Gaps = 29/170 (17%) Query: 21 TGFSQASLLRLHHRF--------RALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP 72 T ++ +L H RF R+++ + + + + + L NP +RI F Sbjct: 43 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 102 Query: 73 DGSQ-RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 ++ + F F+ +L+ F DT T D K HYAF+++D D DG + Sbjct: 103 SPAKDSLSFEDFLDLLSVF-----SDTATPDIKS-----------HYAFRIFDFDDDGTL 146 Query: 132 SRHEMLQVLRLMVG----VQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +R ++ +++ + G +++ +++ + D ++E+D D DG ++ EF Sbjct: 147 NREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF 196 >6O20-F nrPDB Length = 169 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 81/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 25 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 84 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 85 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 128 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 129 VMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 166 >2F2P-A nrPDB Length = 179 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 83/164 (50%), Gaps = 27/164 (16%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNP----LGDRIIESFFPDGSQR 77 ++ + F D++ G ++ +L + +L NP L D +I DG+ Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 63 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 64 IDFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELR 107 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 108 HVMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 146 >1UHN-A nrPDB Length = 189 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 43/169 (25%), Positives = 80/169 (47%), Gaps = 26/169 (15%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQIGALAVNP----LGDRI 66 D + + R+T FS + + L+ F+ + G +++ + Q + N DR+ Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFADRV 59 Query: 67 IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLD 126 + F + + F F R L+ F P P++ +K+H++FQLYDL Sbjct: 60 FDLFDTKHNGILGFEEFARALSVFHP-------------NAPID---DKIHFSFQLYDLK 103 Query: 127 RDGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAV 172 + G I R E+ Q++ + G+ + + +E+I D+T +EAD DG + Sbjct: 104 QQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 152 >2ZFD-A nrPDB Length = 226 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 26/171 (15%) Query: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQIGALAVNP----LGD 64 + D + + R+T FS + + L+ F+ + G +++ + Q + N D Sbjct: 30 LGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ-LALFKTNKKESLFAD 88 Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 R+ + F + + F F R L+ F P P++ +K+H++FQLYD Sbjct: 89 RVFDLFDTKHNGILGFEEFARALSVFHP-------------NAPID---DKIHFSFQLYD 132 Query: 125 LDRDGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAV 172 L + G I R E+ Q++ + G+ + + +E+I D+T +EAD DG + Sbjct: 133 LKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKI 183 >5I0I-E nrPDB Length = 145 Score = 53.5 bits (127), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 81/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 3 LTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 62 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 63 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 106 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 107 VMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 144 >3WFN-B nrPDB Length = 182 Score = 53.5 bits (127), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 81/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 11 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 70 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 71 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 114 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ +G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 115 VM-TNLGEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 152 >3EK4-A nrPDB Length = 451 Score = 53.5 bits (127), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 81/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 307 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 366 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 367 DFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 410 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 411 VMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 448 >3U0K-A nrPDB Length = 442 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 80/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG + Sbjct: 298 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTI 357 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E + + AF+++D D +G IS E+ Sbjct: 358 DFPEFLIMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYISAAELRH 401 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 402 VMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 439 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 20/104 (19%) Query: 78 VDFPGFVRVLAH----FRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 V+FP V+ + P D+ TE Q + E AF L+D D DG I+ Sbjct: 275 VNFPSNGAVMQKKTKGWEPTRDQLTEEQIAEFKE-----------AFSLFDKDGDGTITT 323 Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 E+ V+R + G TE +L+++ + E D DGDG + F EF Sbjct: 324 KELGTVMRSL-GQNPTEAELQDM----INEVDADGDGTIDFPEF 362 >6HCS-A nrPDB Length = 167 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D+E ++ AF+++D D +G IS E+ Sbjct: 65 DFPEFLTMMA--RKMKDTDSE--------------EEIREAFRVFDKDGNGYISAAELRH 108 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + +G ++T+E++ D ++EAD DGDG V++ EF + + Sbjct: 109 FMT-NLGEKLTDEEV----DEMIREADIDGDGQVNYEEFVQMM 146 >2LCP-A nrPDB Length = 190 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/156 (31%), Positives = 71/156 (45%), Gaps = 22/156 (14%) Query: 41 NKKGYLSRMDLQQI--GALAVNPLGD-------RIIESFFPDGSQRVDFPGFVRVLAHFR 91 +K Y + ++QQ G + P G +I + FFP G F FV F Sbjct: 17 TRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDP-TKFATFV--FNVFD 73 Query: 92 PVEDEDTETQDPKKPEPLNSRRN---KLHYAFQLYDLDRDGKISRHEMLQV---LRLMVG 145 +D E + + + SR KL +AF+LYDLD DG I+R+EML + + MVG Sbjct: 74 ENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVG 133 Query: 146 VQVTEEQLENI----ADRTVQEADEDGDGAVSFVEF 177 V + EN DR D++ DG ++ EF Sbjct: 134 NTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEF 169 >1CLM-A nrPDB Length = 148 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 40/163 (24%), Positives = 82/163 (50%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 4 LTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++++D+E + L AF+++D D +G IS E+ Sbjct: 64 DFPEFLSLMA--RKMKEQDSEEE--------------LIEAFKVFDRDGNGLISAAELRH 107 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ +G ++T++++ D ++EAD DGDG +++ EF + + Sbjct: 108 VMT-NLGEKLTDDEV----DEMIREADIDGDGHINYEEFVRMM 145 >1TOP-A nrPDB Length = 162 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 22/164 (13%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRIIESFFPDGSQRV 78 S+ + F D + G +S +L + L NP D IIE DGS + Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 73 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DF F+ ++ K + +L F+++D + DG I E+ + Sbjct: 74 DFEEFLVMMVR-------------QMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGE 120 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 +LR G VTEE +E++ ++++D++ DG + F EF K +E Sbjct: 121 ILRA-TGEHVTEEDIEDL----MKDSDKNNDGRIDFDEFLKMME 159 >5ZOR-A nrPDB Length = 149 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 28/66 (42%), Positives = 40/66 (60%), Gaps = 5/66 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AFQL+DLD+ GKIS + +V +L+ E +++ + EADEDGDG VSF EF Sbjct: 86 AFQLFDLDKKGKISFANLKEVAKLL-----GENPGDDVLQEMIAEADEDGDGEVSFEEFK 140 Query: 179 KSLEKM 184 + +M Sbjct: 141 SVMMQM 146 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 16/65 (24%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 ++ AF L+D D G I EM ++ + + +++E RTV+ + + +G + + Sbjct: 8 QIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVE----RTVRSMNTNANGLIEY 63 Query: 175 VEFTK 179 EF + Sbjct: 64 GEFER 68 >1GGZ-A nrPDB Length = 148 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 40/163 (24%), Positives = 79/163 (48%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + + DG+ V Sbjct: 4 LTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTV 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A R ++D D E + + AF+++D D +G +S E+ Sbjct: 64 DFPEFLGMMA--RKMKDTDNEEE--------------IREAFRVFDKDGNGFVSAAELRH 107 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++++E++ D ++ AD DGDG V++ EF + L Sbjct: 108 VMTRL-GEKLSDEEV----DEMIRAADTDGDGQVNYEEFVRVL 145 >4I2Y-A nrPDB Length = 421 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/182 (24%), Positives = 85/182 (46%), Gaps = 33/182 (18%) Query: 12 PDGDSIRRETGFSQAS--------LLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPL 62 PDG ++++T +A+ + F D++ G ++ +L + +L NP Sbjct: 258 PDGPVMQKKTMGWEATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPT 317 Query: 63 GDRI---IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 + I DG DFP F+ ++A R + D D+E + + A Sbjct: 318 EAELQDMINEVDADGDGTFDFPEFLTMMA--RKMNDTDSEEE--------------IREA 361 Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+++D D +G I E+ V+ + G ++T+E++ D ++ AD DGDG V++ EF + Sbjct: 362 FRVFDKDGNGYIGAAELRHVMTDL-GEKLTDEEV----DEMIRVADIDGDGQVNYEEFVQ 416 Query: 180 SL 181 + Sbjct: 417 MM 418 >6EPA-A nrPDB Length = 187 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 16/124 (12%) Query: 65 RIIESFFPDGSQRVDFPGFVR-VLAHFRPVEDEDTETQDPKKPEPLNSRRN---KLHYAF 120 +I + FFPDG D F V F D E ++ + + SR N KLH+AF Sbjct: 50 KIYKQFFPDG----DPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAF 105 Query: 121 QLYDLDRDGKISRHEMLQV---LRLMVGVQVTEEQLENI----ADRTVQEADEDGDGAVS 173 +LYD+D DG I+R EM + + MVG Q E EN D+ + D++ D ++ Sbjct: 106 RLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTED-ENTPQKRVDKIFDQMDKNHDDRLT 164 Query: 174 FVEF 177 EF Sbjct: 165 LEEF 168 >5T7C-A nrPDB Length = 193 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 39/179 (21%) Query: 17 IRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD------RIIESF 70 +R T F+ L + F L G+L+ + ++I A P GD + +F Sbjct: 16 LRENTEFTDHELQEWYKGF--LKDCPTGHLTVDEFKKIYA-NFFPYGDASKFAEHVFRTF 72 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSR---RNKLHYAFQLYDLDR 127 +G +DF F+ L+ + SR KL +AF +YDLD Sbjct: 73 DTNGDGTIDFREFIIALS--------------------VTSRGKLEQKLKWAFSMYDLDG 112 Query: 128 DGKISRHEMLQVLRLMVGVQVT-------EEQLENIADRTVQEADEDGDGAVSFVEFTK 179 +G ISR EML++++ + + + E E D+ ++ D + DG +S EF + Sbjct: 113 NGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIR 171 >1JBA-A nrPDB Length = 204 Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 12/78 (15%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQV------LRLMVGVQVTEEQL------ENIADRTV 161 +KL + F++YD DR+G I R E+L + L+ V+V EQ E + DR Sbjct: 95 HKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIF 154 Query: 162 QEADEDGDGAVSFVEFTK 179 DE+GDG +S EF + Sbjct: 155 LLVDENGDGQLSLNEFVE 172 >3O4Y-A nrPDB Length = 196 Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 27/159 (16%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRV 86 +L F LD KG ++++ L+ + L + P D +++ DGS +D+ F+ Sbjct: 56 KLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFLAA 115 Query: 87 LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV 146 R + + ++ AF+++D+D DG+I+ E+ VL G Sbjct: 116 AIDRRQLS------------------KKLIYCAFRVFDVDNDGEITTAELAHVL--FNGN 155 Query: 147 Q---VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 + +TE + N + ++E D++GDG + F EF++ ++ Sbjct: 156 KRGNITERDV-NQVKKMIREVDKNGDGKIDFYEFSEMMK 193 >2LAP-A nrPDB Length = 167 Score = 46.6 bits (109), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 20/157 (12%) Query: 31 LHHRFRALDRNKKGYLSRMDL-QQIGALAVNPLGDRIIE---SFFPDGSQRVDFPGFVRV 86 L FR D++K GY++ DL + + P +IE + VDF FV + Sbjct: 27 LREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVEL 86 Query: 87 LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV 146 + E D +L AF+ +D + DG+IS E+ + +R ++G Sbjct: 87 MGPKLLAETADMIGV------------KELRDAFREFDTNGDGEISTSELREAMRKLLGH 134 Query: 147 QVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 QV +E I +++ D +GDG V F EF + + + Sbjct: 135 QVGHRDIEEI----IRDVDLNGDGRVDFEEFVRMMSR 167 >3DD4-A nrPDB Length = 229 Score = 46.2 bits (108), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 49/81 (60%), Gaps = 9/81 (11%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL---MVGVQVTEEQLENIADRT-----VQ 162 + + KL++AF LYD+++DG I++ EML +++ M+G + T L+ A R Q Sbjct: 135 TVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMG-KCTYPVLKEDAPRQHVETFFQ 193 Query: 163 EADEDGDGAVSFVEFTKSLEK 183 + D++ DG V+ EF +S +K Sbjct: 194 KMDKNKDGVVTIDEFIESCQK 214 >3KF9-A nrPDB Length = 149 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 25/166 (15%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGSQR 77 G ++ + F D + G + +L+ + AL P + I I DGS Sbjct: 1 GLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGT 60 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +DF F++++ D R ++ AF+L+D D GKIS + Sbjct: 61 IDFEEFLQMMTAKMGERD----------------SREEIMKAFRLFDDDETGKISFKNLK 104 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 +V + + G +T+E+L+ + D EAD DGDG V+ EF + ++K Sbjct: 105 RVAKEL-GENMTDEELQEMID----EADRDGDGEVNEEEFFRIMKK 145 >2KN2-A nrPDB Length = 92 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 46/67 (68%), Gaps = 5/67 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF+++D D++G IS E+ V+ + +G ++T+E++E + ++EAD DGDG V++ Sbjct: 10 ELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQM----IKEADLDGDGQVNY 64 Query: 175 VEFTKSL 181 EF K + Sbjct: 65 EEFVKMM 71 >2TN4-A nrPDB Length = 159 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 22/164 (13%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDL----QQIGALAVNPLGDRIIESFFPDGSQRV 78 S+ + F D + G +S +L + +G D IIE DGS + Sbjct: 11 LSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTI 70 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DF F+ ++ K + +L F+++D + DG I E+ + Sbjct: 71 DFEEFLVMMVR-------------QMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAE 117 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 + R G VT+E++E++ +++ D++ DG + F EF K +E Sbjct: 118 IFRA-SGEHVTDEEIESL----MKDGDKNNDGRIDFDEFLKMME 156 >2L2E-A nrPDB Length = 190 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 39/177 (22%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD------RIIESFFP 72 R T F + L + + F G+L++ + Q+I P GD + F Sbjct: 18 RSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYK-QFFPFGDPSAFAEYVFNVFDA 74 Query: 73 DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSR---RNKLHYAFQLYDLDRDG 129 D + +DF F+ L+ + SR +KL +AFQLYDLD +G Sbjct: 75 DKNGYIDFKEFICALS--------------------VTSRGELNDKLIWAFQLYDLDNNG 114 Query: 130 KISRHEMLQV---LRLMVGVQVT----EEQLENIADRTVQEADEDGDGAVSFVEFTK 179 IS EML++ + MVG V E+ E ++ D++ DG ++ EF + Sbjct: 115 LISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 >5YPX-A nrPDB Length = 223 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 66/145 (45%), Gaps = 27/145 (18%) Query: 38 LDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHF-RPVEDE 96 +DRN L R L Q + + L DR+ +F D + +V L+ F R DE Sbjct: 62 MDRN----LFRDILHQKFNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDE 117 Query: 97 DTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQ---- 152 K+ Y F ++DL+ DG ISR EM Q+L+ + Q TEE Sbjct: 118 ------------------KMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPTEEDPDEG 159 Query: 153 LENIADRTVQEADEDGDGAVSFVEF 177 ++++ + +++ D D D +S +F Sbjct: 160 IKDLVEIALKKMDHDHDSRLSKKDF 184 >2JUL-A nrPDB Length = 256 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 47/77 (61%), Gaps = 9/77 (11%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRL---MVG-----VQVTEEQLENIADRTVQEADE 166 KL +AF LYD+++DG I++ EML +++ M+G + + LE++ +R Q+ D Sbjct: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV-ERFFQKMDR 224 Query: 167 DGDGAVSFVEFTKSLEK 183 + DG V+ EF ++ +K Sbjct: 225 NQDGVVTIDEFLETCQK 241 >2GGM-A nrPDB Length = 172 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 38/131 (29%), Positives = 66/131 (50%), Gaps = 24/131 (18%) Query: 56 ALAVNPLGDRI---IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSR 112 AL P + I I +G+ +++F F+ V+ + ++DT Sbjct: 59 ALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQ--KMSEKDT-------------- 102 Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 + ++ AF+L+D D GKIS + +V + + G +T+E+L+ + D EAD DGDG V Sbjct: 103 KEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMID----EADRDGDGEV 157 Query: 173 SFVEFTKSLEK 183 S EF + ++K Sbjct: 158 SEQEFLRIMKK 168 Score = 34.7 bits (78), Expect = 0.028, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 5/92 (5%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 KPE ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E Sbjct: 22 KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL-GFEPKKEEIKKM----ISEI 76 Query: 165 DEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 D++G G ++F +F + + E+ ILK Sbjct: 77 DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILK 108 >2NA0-A nrPDB Length = 205 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 3/72 (4%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL---ENIADRTVQEADEDGDGA 171 KL + F+LYD+D +G I R E+L ++R + + + E D + D +GDG Sbjct: 91 KLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGE 150 Query: 172 VSFVEFTKSLEK 183 +S EF + ++K Sbjct: 151 LSLEEFMEGVQK 162 >2R2I-A nrPDB Length = 198 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 42/74 (56%), Gaps = 2/74 (2%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL--ENIADRTVQEADEDGDGAV 172 KL + F+LYD+D +G I R E+L +++ + + E + E + + D +GDG + Sbjct: 89 KLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGEL 148 Query: 173 SFVEFTKSLEKMDV 186 S EF + ++K +V Sbjct: 149 SLEEFMEGVQKDEV 162 >2ROB-A nrPDB Length = 70 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 46/67 (68%), Gaps = 5/67 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF+++D D++G IS E+ V+ + +G ++T+E++E + ++EAD DGDG V++ Sbjct: 5 ELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQM----IKEADLDGDGQVNY 59 Query: 175 VEFTKSL 181 EF K + Sbjct: 60 EEFVKMM 66 >2OBH-A nrPDB Length = 143 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 25/157 (15%) Query: 31 LHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGSQRVDFPGFVRV 86 + F D + G + +L+ + AL P + I I +G+ +++F F+ V Sbjct: 8 IREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTV 67 Query: 87 LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV 146 + + ++DT + ++ AF+L+D D GKIS + +V + + G Sbjct: 68 MTQ--KMSEKDT--------------KEEILKAFKLFDDDETGKISFKNLKRVAKEL-GE 110 Query: 147 QVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 +T+E+L+ + D EAD DGDG VS EF + ++K Sbjct: 111 NLTDEELQEMID----EADRDGDGEVSEQEFLRIMKK 143 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Query: 112 RRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGA 171 ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E D++G G Sbjct: 4 QKQEIREAFDLFDADGTGTIDVKELKVAMRAL-GFEPKKEEIKKM----ISEIDKEGTGK 58 Query: 172 VSFVEF 177 ++F +F Sbjct: 59 MNFGDF 64 >4ZCV-A nrPDB Length = 165 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 33/153 (21%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGS----QRVDFPGFV 84 R F+ALDRN G + +LQ+ + L + PLG E F G ++DF F+ Sbjct: 14 RYETLFQALDRNGDGVVDIGELQEGLRNLGI-PLGQDAEEKIFTTGDVNKDGKLDFEEFM 72 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 + L +D +K K+ AF+ D + DGKI E++Q L+ + Sbjct: 73 KYL-------------KDHEK---------KMKLAFKSLDKNNDGKIEASEIVQSLQTL- 109 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 G+ ++E+Q E I +Q D DG V + E+ Sbjct: 110 GLTISEQQAELI----LQSIDVDGTMTVDWNEW 138 >2I08-A nrPDB Length = 78 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 24/59 (40%), Positives = 36/59 (61%), Gaps = 5/59 (8%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF LYD D DG I+ E+ V+R +G+ TE +L+++ + E D DG+G + F EF Sbjct: 15 AFSLYDKDGDGTITTKELGTVMR-SLGLNPTEAELQDM----INEVDADGNGTIDFPEF 68 >4N5X-A nrPDB Length = 199 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 33/153 (21%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGS----QRVDFPGFV 84 R F+ALDRN G + +LQ+ + L + PLG E F G ++DF F+ Sbjct: 23 RYETLFQALDRNGDGVVDIGELQEGLRNLGI-PLGQDAEEKIFTTGDVNKDGKLDFEEFM 81 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 + L K+ AF+ D + DGKI E++Q L+ + Sbjct: 82 KYL----------------------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTL- 118 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 G+ ++E+Q E I +Q D DG V + E+ Sbjct: 119 GLTISEQQAELI----LQSIDVDGTMTVDWNEW 147 >2LMV-A nrPDB Length = 148 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 77/159 (48%), Gaps = 27/159 (16%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNP----LGDRIIESFFPDGSQRV 78 ++ + F D+ G ++ +L + L NP L D I E+ + Q + Sbjct: 5 TEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQ-L 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 +F F ++A + + + DTE + + AF+++D D DG IS E L+ Sbjct: 64 NFTEFCGIMA--KQMRETDTEEE--------------MREAFKIFDRDGDGFISPAE-LR 106 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 + + +G +VT+E++ D ++EAD DGDG +++ EF Sbjct: 107 FVMINLGEKVTDEEI----DEMIREADFDGDGMINYEEF 141 >1TNP-A nrPDB Length = 90 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 5/63 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF ++D D G IS E+ V+R M+G T+E+L+ I ++E DEDG G + F Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEELDAI----IEEVDEDGSGTIDF 75 Query: 175 VEF 177 EF Sbjct: 76 EEF 78 >1TRF-A nrPDB Length = 76 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 5/63 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF ++D D G IS E+ V+R M+G T+E+L+ I ++E DEDG G + F Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEELDAI----IEEVDEDGSGTIDF 64 Query: 175 VEF 177 EF Sbjct: 65 EEF 67 >5M6C-E nrPDB Length = 193 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 7/72 (9%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT-------EEQLENIADRTVQEADED 167 KL +AF +YDLD +G ISR EML++++ + + + E E ++ ++ D + Sbjct: 100 KLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 168 GDGAVSFVEFTK 179 DG +S EF + Sbjct: 160 NDGKLSLEEFIR 171 >5H7D-E nrPDB Length = 120 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 11/82 (13%) Query: 102 DPKKPEPLNSRRNKLHY------AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLEN 155 DP + L + KL+ AF L+D D DG I+ E+ V+R +G TE +L++ Sbjct: 38 DPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMR-SLGQNPTEAELQD 96 Query: 156 IADRTVQEADEDGDGAVSFVEF 177 + + E D DG+G + F EF Sbjct: 97 M----INEVDADGNGTIDFPEF 114 >2E6W-A nrPDB Length = 100 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 7/82 (8%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTV 161 + + KL +AF LYD+++DG I++ EML +++ + + + E+ +R Sbjct: 4 MGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFF 63 Query: 162 QEADEDGDGAVSFVEFTKSLEK 183 ++ D + DG V+ EF ++ +K Sbjct: 64 EKMDRNQDGVVTIEEFLEACQK 85 >3KHE-A nrPDB Length = 191 Score = 42.7 bits (99), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 48/163 (29%), Positives = 69/163 (42%), Gaps = 27/163 (16%) Query: 31 LHHRFRALDRNKKGYLSRMDL-------QQIGALAVNPLGDRIIESFFPDGSQRVDF--P 81 L FR LD N G L R +L Q V+ L IE+ Q VDF Sbjct: 42 LTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRN 101 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 G++ + F V + L R +L AFQ +D D GKI+ E+ R Sbjct: 102 GYIEY-SEFVTV----------CMDKQLLLSRERLLAAFQQFDSDGSGKITNEELG---R 147 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 L +V +E + +QE D++ DG V F EF + ++K+ Sbjct: 148 LFGVTEVDDETWHQV----LQECDKNNDGEVDFEEFVEMMQKI 186 >1V1G-A nrPDB Length = 222 Score = 42.7 bits (99), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 19/121 (15%) Query: 60 NPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 N DRI + F + ++F FVR L F P P++ K+ +A Sbjct: 73 NLFADRIFDVFDVKRNGVIEFGEFVRSLGVFHP-------------SAPVHE---KVKFA 116 Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVG---VQVTEEQLENIADRTVQEADEDGDGAVSFVE 176 F+LYDL + G I R E+ +++ ++ + ++E+ +E + D+ +AD DG + E Sbjct: 117 FKLYDLRQTGFIEREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDE 176 Query: 177 F 177 + Sbjct: 177 W 177 >5UKG-A nrPDB Length = 419 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 31/166 (18%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG Sbjct: 275 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTF 334 Query: 79 DFPGFVRVLA---HFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 DFP F+ ++A +R E+E E AF+++D D +G I E Sbjct: 335 DFPEFLTMMARKMSYRVTEEEIRE-------------------AFRVFDKDGNGYIGAAE 375 Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + V+ + G ++T+E++ D ++ AD DGDG V++ EF + + Sbjct: 376 LRHVMTDL-GEKLTDEEV----DEMIRVADIDGDGQVNYEEFVQMM 416 >2RO9-A nrPDB Length = 69 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 44/67 (65%), Gaps = 5/67 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF+++D D++G IS E+ V+ + G ++T+E++ D ++EAD DGDG +++ Sbjct: 5 ELKEAFRVFDKDQNGFISAAELRHVMTNL-GEKLTDEEV----DEMIREADVDGDGQINY 59 Query: 175 VEFTKSL 181 EF K + Sbjct: 60 EEFVKVM 66 Score = 30.0 bits (66), Expect = 0.75, Method: Compositional matrix adjust. Identities = 15/61 (24%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQI----GALAVNPLGDRIIESFFPDGSQRVDFPGFVRV 86 L FR D+++ G++S +L+ + G + D +I DG ++++ FV+V Sbjct: 6 LKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKV 65 Query: 87 L 87 + Sbjct: 66 M 66 >3HZT-A nrPDB Length = 467 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 51/169 (30%), Positives = 73/169 (43%), Gaps = 28/169 (16%) Query: 31 LHHRFRALDRNKKGYLSRMDL-------QQIGALAVNPLGDRIIESFFPDGSQRVDF--P 81 L FR LD N G L R +L Q V+ L IE+ Q VDF Sbjct: 316 LTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDRN 375 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 G++ E +E + L R +L AFQ +D D GKI+ E+ R Sbjct: 376 GYI-----------EYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELG---R 421 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM-DVEQK 189 L +V +E + +QE D++ DG V F EF + ++K+ DV+ K Sbjct: 422 LFGVTEVDDETWHQV----LQECDKNNDGEVDFEEFVEMMQKICDVKVK 466 >3K21-A nrPDB Length = 191 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 32/156 (20%), Positives = 72/156 (46%), Gaps = 21/156 (13%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRV 86 +L F LD + KGY+++ L+ + L + D +++ DGS ++D+ F+ Sbjct: 53 KLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFIAA 112 Query: 87 LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV 146 + + + ++ AF+++D+D DG+I+ E+ +L Sbjct: 113 ALDRKQLS------------------KKLIYCAFRVFDVDNDGEITTAELAHILYNGNKK 154 Query: 147 QVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 ++ N R +++ D++ DG + F EF++ ++ Sbjct: 155 GNITQRDVNRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 >4JWQ-A nrPDB Length = 199 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/158 (21%), Positives = 71/158 (44%), Gaps = 21/158 (13%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 L +L F LD + KG +++ L+ + L + D +++ DGS R+D+ F+ Sbjct: 57 LQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 + + + ++ AF+++D+D DG+I+ E+ +L Sbjct: 117 AAALDRKHLS------------------KKLIYCAFRVFDVDNDGEITTAELAHILYNGN 158 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 ++ N + +QE D++ DG + F EF + ++ Sbjct: 159 KKGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMK 196 >3J04-B nrPDB Length = 143 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/160 (23%), Positives = 70/160 (43%), Gaps = 23/160 (14%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVDFP 81 F Q+ + F +D+N+ G++ + DL + ++ NP D +E + ++F Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPT-DEYLEGMMSEAPGPINFT 59 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 F+ + E DP+ + + AF +D + G I + ++L Sbjct: 60 MFLTMFG-------EKLNGTDPE---------DVIRNAFACFDEEASGFIHEDHLRELLT 103 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 M G + T+E++ D +EA D G ++VEFT+ L Sbjct: 104 TM-GDRFTDEEV----DEMYREAPIDKKGNFNYVEFTRIL 138 >2K7C-A nrPDB Length = 72 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 4/69 (5%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF+ +D + DG+IS E+ + +R ++G QV +E I +++ D +GDG V F Sbjct: 8 ELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVDF 63 Query: 175 VEFTKSLEK 183 EF + + + Sbjct: 64 EEFVRMMSR 72 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPD----GSQRVDFPGFVR 85 L FR D N G +S +L++ + L + +G R IE D G RVDF FVR Sbjct: 9 LRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVR 68 Query: 86 VLA 88 +++ Sbjct: 69 MMS 71 >2JU0-A nrPDB Length = 190 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/156 (29%), Positives = 67/156 (42%), Gaps = 30/156 (19%) Query: 45 YLSRMDLQQI--GALAVNPLGD-------RIIESFFPDGSQRVDFPGFVRVLAHFRPVED 95 Y R ++QQ G L P G +I + FFP GS DF H V D Sbjct: 21 YFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-DFAN------HLFTVFD 73 Query: 96 EDT-------ETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV---LRLMVG 145 +D E + KL +AF+LYDL+ DG I+ EML + + M+G Sbjct: 74 KDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMG 133 Query: 146 VQVTEEQLENIADRTVQE----ADEDGDGAVSFVEF 177 VT + E + V++ D++ DG ++ EF Sbjct: 134 SMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 >5COC-A nrPDB Length = 130 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 5/59 (8%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF L+D D DG I+ E+ V+R +G TE +L+++ + E D DG+G + F EF Sbjct: 68 AFSLFDKDGDGTITTKELGTVMR-SLGQNPTEAELQDM----INEVDADGNGTIDFPEF 121 >4Q57-A nrPDB Length = 65 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 5/59 (8%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF L+D D DG I+ E+ V+R + G TE +L+++ + E D DG+G + F EF Sbjct: 7 AFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDM----INEVDADGNGTIDFPEF 60 >5VLN-A nrPDB Length = 120 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 6/67 (8%) Query: 112 RRNKLHYAFQLYDLD-RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++N+ AF ++ L DG IS E+ +V+R M+G T E+L+ + D E DEDG G Sbjct: 16 QKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGSG 70 Query: 171 AVSFVEF 177 V F EF Sbjct: 71 TVDFDEF 77 >2K2I-A nrPDB Length = 79 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 5/65 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF+L+D D GKIS + +V + + G +T+E+L+ + D EAD DGDG VS EF Sbjct: 16 AFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMID----EADRDGDGEVSEQEFL 70 Query: 179 KSLEK 183 + ++K Sbjct: 71 RIMKK 75 >1S1E-A nrPDB Length = 224 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 38/190 (20%) Query: 12 PDG-DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF 70 P+G + + +T F++ L L+ F+ + G ++ +QI A F Sbjct: 36 PEGLEQLEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYA------------QF 81 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLN--------SRRNKLHYAFQL 122 FP G AH+ + T+T K + + + KL + F L Sbjct: 82 FPHGD--------ASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNL 133 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGAVSFV 175 YD+++DG I++ EM+ +++ + + + E+ D Q+ D++ DG V+ Sbjct: 134 YDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLD 193 Query: 176 EFTKSLEKMD 185 EF +S ++ D Sbjct: 194 EFLESCQEDD 203 >1M39-A nrPDB Length = 89 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 5/65 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF+L+D D GKIS + +V + +G +T+E+L+ + D EAD DGDG VS EF Sbjct: 26 AFKLFDDDETGKISFKNLKRVAK-ELGENLTDEELQEMID----EADRDGDGEVSEQEFL 80 Query: 179 KSLEK 183 + ++K Sbjct: 81 RIMKK 85 >1S6C-A nrPDB Length = 183 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 38/190 (20%) Query: 12 PDG-DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF 70 P+G + + +T F++ L L+ F+ + G ++ +QI A F Sbjct: 3 PEGLEQLEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYA------------QF 48 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLN--------SRRNKLHYAFQL 122 FP G AH+ + T+T K + + + KL + F L Sbjct: 49 FPHGD--------ASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNL 100 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGAVSFV 175 YD+++DG I++ EM+ +++ + + + E+ D Q+ D++ DG V+ Sbjct: 101 YDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLD 160 Query: 176 EFTKSLEKMD 185 EF +S ++ D Sbjct: 161 EFLESCQEDD 170 >5D43-A nrPDB Length = 178 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/74 (36%), Positives = 45/74 (60%), Gaps = 5/74 (6%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 + ++ AF+L+D D GKIS + +V + G +T+E+L+ + D EAD DGDG V Sbjct: 103 KEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMID----EADRDGDGEV 157 Query: 173 SFVEFTKSLEKMDV 186 + EF K ++K ++ Sbjct: 158 NEEEFLKIMKKTNL 171 Score = 35.0 bits (79), Expect = 0.023, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 5/92 (5%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 KPE ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E Sbjct: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL-GFEPRKEEMKKM----ISEV 76 Query: 165 DEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 D++ G +SF +F + + E+ ILK Sbjct: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILK 108 >6IIE-A nrPDB Length = 93 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 40/71 (56%), Gaps = 4/71 (5%) Query: 114 NKLHYAFQLYDLDRDGKISRHE----MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 +KL + F+LYD DR+G + E +LQ++R+ + +L I ++E D DG Sbjct: 9 DKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGS 68 Query: 170 GAVSFVEFTKS 180 G+VS E+ ++ Sbjct: 69 GSVSQAEWVRA 79 >2RO8-A nrPDB Length = 79 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 5/59 (8%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF L+D D DG I+ E+ V+R +G TE +L+++ + E D DG+G + F EF Sbjct: 15 AFSLFDKDGDGCITTKELGTVMR-SLGQNPTEAELQDM----INEVDADGNGTIDFPEF 68 >3IFK-A nrPDB Length = 90 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 5/63 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L+++ + E D DG+G + F Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQDM----INEVDADGNGTIDF 65 Query: 175 VEF 177 EF Sbjct: 66 PEF 68 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 6/81 (7%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + I DG+ + Sbjct: 4 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRPVEDEDTE 99 DFP F+ ++A R ++D D+E Sbjct: 64 DFPEFLTMMA--RKMKDTDSE 82 >1BJF-A nrPDB Length = 193 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 37/152 (24%) Query: 44 GYLSRMDLQQIGALAVNPLGD------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDED 97 G+LS + ++I P GD + +F +G +DF F+ L+ Sbjct: 41 GHLSMEEFKKIYG-NFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALS--------- 90 Query: 98 TETQDPKKPEPLNSR---RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT----- 149 + SR KL +AF +YDLD +G IS+ EML++++ + + + Sbjct: 91 -----------VTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMP 139 Query: 150 --EEQLENIADRTVQEADEDGDGAVSFVEFTK 179 E E ++ ++ D + DG +S EF + Sbjct: 140 EDESTPEKRTEKIFRQMDTNRDGKLSLEEFIR 171 >2N7L-C nrPDB Length = 141 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 6/67 (8%) Query: 112 RRNKLHYAFQLYDLD-RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++N+ AF ++ L DG IS E+ +V+R M+G T E+L+ + D E DEDG G Sbjct: 31 QKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGSG 85 Query: 171 AVSFVEF 177 V F EF Sbjct: 86 TVDFDEF 92 >1DTL-A nrPDB Length = 161 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 6/67 (8%) Query: 112 RRNKLHYAFQLYDLD-RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++N+ AF ++ L DG IS E+ +V+R M+G T E+L+ + D E DEDG G Sbjct: 16 QKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGSG 70 Query: 171 AVSFVEF 177 V F EF Sbjct: 71 TVDFDEF 77 >2JNF-A nrPDB Length = 158 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 17/113 (15%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 ++I+ F P G+ +DF F + A F E PE + + +L AF+LYD Sbjct: 54 QLIDEFDPFGNGDIDFDSFKIIGARFLGEE---------VNPEQM---QQELREAFRLYD 101 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 + +G IS M ++L ++ E D + E D DG G V F EF Sbjct: 102 KEGNGYISTDVMREIL-----AELDETLSSEDLDAMIDEIDADGSGTVDFEEF 149 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG----DRIIESFFPDGSQRVDFPGFVR 85 L FR D+ GY+S +++I A L D +I+ DGS VDF F+ Sbjct: 92 ELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMG 151 Query: 86 VLA 88 V+ Sbjct: 152 VMT 154 >1FW4-A nrPDB Length = 71 Score = 39.7 bits (91), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 41/63 (65%), Gaps = 5/63 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF+++D D +G IS E+ V+ + G ++T+E++ D ++EAD DGDG V++ EF Sbjct: 11 AFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFV 65 Query: 179 KSL 181 + + Sbjct: 66 QMM 68 Score = 28.5 bits (62), Expect = 2.1, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQI----GALAVNPLGDRIIESFFPDGSQRVDFPGFVRV 86 + FR D++ GY+S +L+ + G + D +I DG +V++ FV++ Sbjct: 8 IREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQM 67 Query: 87 LA 88 + Sbjct: 68 MT 69 >5OTJ-D nrPDB Length = 110 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 F+ +D + DGKIS E+ LR + E Q R + E D DGDG + F EF Sbjct: 9 FKRFDTNGDGKISLSELTDALRTLGSTSADEVQ------RMMAEIDTDGDGFIDFNEF 60 >3NCG-A nrPDB Length = 486 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 71/171 (41%), Gaps = 40/171 (23%) Query: 30 RLHHRFRALDRNKKGYLSRMDL-------QQIGALAVNPL----GDRI---IESFFP--- 72 +L FR LD N G L R +L ++ + N L G I I+S P Sbjct: 332 QLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLD 391 Query: 73 -DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 DGS +++ F+ + R ++ AF+++D D GKI Sbjct: 392 MDGSGSIEYSEFIA-----------------SAIDRTILLSRERMERAFKMFDKDGSGKI 434 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 S E+ ++ + E+LE+I +++ D + DG V F EF + L+ Sbjct: 435 STKELFKLFS-QADSSIQMEELESI----IEQVDNNKDGEVDFNEFVEMLQ 480 >2KSZ-A nrPDB Length = 76 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF L+D D DG I+ E+ V+R + TEE+L+++ + E D DG+G + F EF Sbjct: 15 AFGLFDKDGDGCITVEELATVIRSL-DQNPTEEELQDM----ISEVDADGNGTIEFDEFL 69 Query: 179 KSLEK 183 + K Sbjct: 70 SLMAK 74 >2OPO-A nrPDB Length = 86 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 6/59 (10%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 F+ +D + DGKIS E+ L+ + V E + R + E D DGDG +SF EFT Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLGSVTPDEVR------RMMAEIDTDGDGFISFDEFT 69 >2M97-A nrPDB Length = 69 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L F+++D D +G I R E ++RL G Q+T+E ++ I ++D D +G + F Sbjct: 4 ELSECFRIFDKDGNGFIDREEFGDIIRL-TGEQLTDEDVDEI----FGDSDTDKNGRIDF 58 Query: 175 VEFTKSLEKM 184 EF K +E + Sbjct: 59 DEFLKMMENV 68 >2LV7-A nrPDB Length = 100 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/63 (39%), Positives = 35/63 (55%), Gaps = 5/63 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF+++D D +G IS+ E+ +R + G E +LE I +Q D DGDG V F EF Sbjct: 41 AFKVFDRDGNGFISKQELGTAMRSL-GYMPNEVELEVI----IQRLDMDGDGQVDFEEFV 95 Query: 179 KSL 181 L Sbjct: 96 TLL 98 Score = 30.0 bits (66), Expect = 0.75, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Query: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDL----QQIGALAVNPLGDRI 66 +P+ S +R + L + F+ DR+ G++S+ +L + +G + + I Sbjct: 18 VPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVI 77 Query: 67 IESFFPDGSQRVDFPGFVRVLA 88 I+ DG +VDF FV +L Sbjct: 78 IQRLDMDGDGQVDFEEFVTLLG 99 >4GJF-A nrPDB Length = 89 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 6/67 (8%) Query: 112 RRNKLHYAFQLY-DLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++N+ AF ++ DG IS E+ +V+R M+G T E+L+ + D E DEDG G Sbjct: 16 QKNEFKAAFDIFVQGAEDGCISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGSG 70 Query: 171 AVSFVEF 177 V F EF Sbjct: 71 TVDFDEF 77 >2LVK-A nrPDB Length = 77 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 F+ +D + DGKIS E+ LR + E Q R + E D DGDG + F EF Sbjct: 8 FKRFDTNGDGKISLSELTDALRTLGSTSADEVQ------RMMAEIDTDGDGFIDFNEF 59 >4RGJ-A nrPDB Length = 520 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 7/70 (10%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF+L+D D GKIS +E+ Q+ L V+ E + + ++E D++ DG + F Sbjct: 455 RLEKAFKLFDKDGSGKISANELAQLFGL---SDVSSECWKTV----LKEVDQNNDGEIDF 507 Query: 175 VEFTKSLEKM 184 EF L K+ Sbjct: 508 KEFRDMLVKL 517 >2M29-A nrPDB Length = 171 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 4/67 (5%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF+ +D DRDG+I+ E+ Q ++G + +L D ++E D +GDG + F Sbjct: 106 ELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTEL----DEMLREMDLNGDGTIDF 161 Query: 175 VEFTKSL 181 EF L Sbjct: 162 DEFVMML 168 >1JC2-A nrPDB Length = 76 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 5/68 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L F+++D + DG I E+ ++LR G V EE +E++ ++++D++ DG + F Sbjct: 11 ELANCFRIFDKNADGFIDIEELGEILR-ATGEHVIEEDIEDL----MKDSDKNNDGRIDF 65 Query: 175 VEFTKSLE 182 EF K +E Sbjct: 66 DEFLKMME 73 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 12/66 (18%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPD--------GSQRVDFP 81 L + FR D+N G++ D++++G + + G+ +IE D R+DF Sbjct: 11 ELANCFRIFDKNADGFI---DIEELGEI-LRATGEHVIEEDIEDLMKDSDKNNDGRIDFD 66 Query: 82 GFVRVL 87 F++++ Sbjct: 67 EFLKMM 72 >1H4B-A nrPDB Length = 84 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 37/59 (62%), Gaps = 6/59 (10%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 F+ +D + DGKIS E+ + L+ + +T ++++++ + E D DGDG +SF EFT Sbjct: 15 FKRFDANGDGKISAAELGEALKTLG--SITPDEVKHM----MAEIDTDGDGFISFQEFT 67 >2M5E-A nrPDB Length = 73 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 41/63 (65%), Gaps = 5/63 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF+++D D +G IS E+ V+ + G ++T++++ D ++EAD DGDG +++ EF Sbjct: 13 AFKVFDRDGNGLISAAELRHVMTNL-GEKLTDDEV----DEMIREADIDGDGHINYEEFV 67 Query: 179 KSL 181 + + Sbjct: 68 RMM 70 >3L19-A nrPDB Length = 214 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 44/177 (24%), Positives = 71/177 (40%), Gaps = 44/177 (24%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL---------QQIGAL---AVNPLGDRIIESFF 71 SQ L FR +D+N G L R +L +++ + D I+ + Sbjct: 58 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 117 Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 D + +D+ FV V + + +D KL AFQ +D D +GKI Sbjct: 118 FDRNGYIDYSEFVTVAMDRKSLLSKD-----------------KLESAFQKFDQDGNGKI 160 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA----DEDGDGAVSFVEFTKSLEKM 184 S E+ V L+++ +T +E D + DG V F EF K ++K+ Sbjct: 161 SVDELASVFG-----------LDHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKL 206 >2KZ2-A nrPDB Length = 94 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 40/63 (63%), Gaps = 5/63 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 AF++ D D +G IS E+ V+ + G ++T+E++ D ++EAD DGDG V++ EF Sbjct: 34 AFRVEDKDGNGYISAAELRHVMTNL-GEKLTDEEV----DEMIREADIDGDGQVNYEEFV 88 Query: 179 KSL 181 + + Sbjct: 89 QMM 91 Score = 26.9 bits (58), Expect = 5.5, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQI----GALAVNPLGDRIIESFFPDGSQRVDFPGFVRV 86 + FR D++ GY+S +L+ + G + D +I DG +V++ FV++ Sbjct: 31 IREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQM 90 Query: 87 LA 88 + Sbjct: 91 MT 92 >3Q5I-A nrPDB Length = 504 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 36/162 (22%), Positives = 70/162 (43%), Gaps = 36/162 (22%) Query: 35 FRALDRNKKGYLSRMDL-----------QQIGALA-VNPLGDRIIESFFPDGSQRVDFPG 82 F+ LD+N G L + +L ++G L V D I++ D + +++ Sbjct: 361 FKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKNGYIEYSE 420 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ V + + E+ +L AF L+D D+ GKI++ E+ + L Sbjct: 421 FISVCMDKQILFSEE-----------------RLRRAFNLFDTDKSGKITKEELANLFGL 463 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 ++E+ ++ + EAD++ D + F EF + K+ Sbjct: 464 ---TSISEKTWNDV----LGEADQNKDNMIDFDEFVSMMHKI 498 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 16/68 (23%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENI---ADRTVQEADEDGD 169 R +L F+ D + DG++ + E+++ ++ + +L+N+ D ++E D D + Sbjct: 354 RKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKN 413 Query: 170 GAVSFVEF 177 G + + EF Sbjct: 414 GYIEYSEF 421 >5VE9-A nrPDB Length = 91 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Query: 97 DTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENI 156 D + K +N +++++ F+ D D+DGKI+R E + + L T+ ++ + Sbjct: 10 DFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGI-LASKFPTTKLEMTAV 68 Query: 157 ADRTVQEADEDGDGAVSFVEFTKSLE 182 AD D DGDG + + EF +L Sbjct: 69 AD----IFDRDGDGYIDYYEFVAALH 90 >3LIJ-A nrPDB Length = 494 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 15/76 (19%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA----DEDG 168 ++KL AFQ +D D +GKIS E+ V L+++ +T +E D + Sbjct: 425 KDKLESAFQKFDQDGNGKISVDELASVF-----------GLDHLESKTWKEMISGIDSNN 473 Query: 169 DGAVSFVEFTKSLEKM 184 DG V F EF K ++K+ Sbjct: 474 DGDVDFEEFCKMIQKL 489 >2I94-A nrPDB Length = 202 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 26/146 (17%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MG+ S A + ++ T F++ L + F L G ++R + Q I + Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSF--LKECPSGRITRQEFQTIYS-KFF 57 Query: 61 PLGD------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN 114 P D + SF + +DF +V L H Sbjct: 58 PEADPKAYAQHVFRSFDANSDGTLDFKEYVIAL-HMTSA----------------GKTNQ 100 Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVL 140 KL +AF LYD+D +G IS++E+L+++ Sbjct: 101 KLEWAFSLYDVDGNGTISKNEVLEIV 126 >4MVF-A nrPDB Length = 506 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 26/161 (16%) Query: 30 RLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 L + F ALD + G LS + L++IG + P +++ + S ++ + F+ Sbjct: 361 NLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLA 420 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG 145 D +T K+ + F+ +D+D +GKIS E L+ + G Sbjct: 421 ATI--------DKQTYLKKEVCLI---------PFKFFDIDGNGKISVEE----LKRIFG 459 Query: 146 VQVTEEQLENIA-DRTVQEADEDGDGAVSFVEFTKSLEKMD 185 E L + A D +QE D +GDG + F EF + K++ Sbjct: 460 RDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 >2LHI-A nrPDB Length = 176 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 9/76 (11%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF- 177 AF L+D D +G IS E+ V+R +G+ +E ++ ++ + E D DG+ + F EF Sbjct: 16 AFALFDKDNNGSISSSELATVMR-SLGLSPSEAEVNDL----MNEIDVDGNHQIEFSEFL 70 Query: 178 ---TKSLEKMDVEQKM 190 ++ L+ D EQ++ Sbjct: 71 ALMSRQLKSNDSEQEL 86 >4DS7-A nrPDB Length = 147 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 9/76 (11%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF- 177 AF L+D D G IS E+ V+R +G+ +E ++ ++ + E D DG+ A+ F EF Sbjct: 16 AFALFDKDNSGSISASELATVMR-SLGLSPSEAEVADL----MNEIDVDGNHAIEFSEFL 70 Query: 178 ---TKSLEKMDVEQKM 190 ++ L+ D EQ++ Sbjct: 71 ALMSRQLKCNDSEQEL 86 >2LHH-A nrPDB Length = 128 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 9/76 (11%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF- 177 AF L+D D +G IS E+ V+R +G+ +E ++ ++ + E D DG+ + F EF Sbjct: 15 AFALFDKDNNGSISSSELATVMR-SLGLSPSEAEVNDL----MNEIDVDGNHQIEFSEFL 69 Query: 178 ---TKSLEKMDVEQKM 190 ++ L+ D EQ++ Sbjct: 70 ALMSRQLKSNDSEQEL 85 >3FWC-A nrPDB Length = 161 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 33/155 (21%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRI--------IESFFPDGSQRVDFPG 82 ++ F D N G+L +L+ +A+ LG + I+ + +G + + Sbjct: 25 IYEAFSLFDMNNDGFLDYHELK----VAMKALGFELPKREILDLIDEYDSEGRHLMKYDD 80 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F V+ + K +PL+ ++ AFQL+D D GKIS + +V + Sbjct: 81 FYIVMG------------EKILKRDPLD----EIKRAFQLFDDDHTGKISIKNLRRVAK- 123 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +G +T+E+L + ++E D DGDG ++ EF Sbjct: 124 ELGETLTDEELRAM----IEEFDLDGDGEINENEF 154 Score = 31.2 bits (69), Expect = 0.29, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQ 162 P E L ++ +++ AF L+D++ DG + HE L+V +G ++ + ++ ++ D Sbjct: 12 PLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHE-LKVAMKALGFELPKREILDLID---- 66 Query: 163 EADEDGDGAVSFVEF 177 E D +G + + +F Sbjct: 67 EYDSEGRHLMKYDDF 81 >1LKJ-A nrPDB Length = 146 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 9/76 (11%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF- 177 AF L+D D +G IS E+ V+R +G+ +E ++ ++ + E D DG+ + F EF Sbjct: 15 AFALFDKDNNGSISSSELATVMR-SLGLSPSEAEVNDL----MNEIDVDGNHQIEFSEFL 69 Query: 178 ---TKSLEKMDVEQKM 190 ++ L+ D EQ++ Sbjct: 70 ALMSRQLKSNDSEQEL 85 >4YZB-A nrPDB Length = 491 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 7/72 (9%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 R +L AF ++D D GKIS E+ + GV + + R + E D + DG V Sbjct: 421 RQRLERAFGMFDADGSGKISSSELATIF----GVSEVDSETWR---RVLAEVDRNNDGEV 473 Query: 173 SFVEFTKSLEKM 184 F EF + L K+ Sbjct: 474 DFEEFRQMLLKL 485 >2AAO-A nrPDB Length = 166 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 38/166 (22%), Positives = 70/166 (42%), Gaps = 30/166 (18%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLS----RMDLQQIGA-LAVNPLGDRIIESFFPDGSQR 77 S+ + L F +D +K G ++ + L+++GA L + + D ++++ D S Sbjct: 21 LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILD-LMQAADVDNSGT 79 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +D+ F+ H +E ED L AF +D D G I+ E+ Sbjct: 80 IDYKEFIAATLHLNKIERED-----------------HLFAAFTYFDKDGSGYITPDELQ 122 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 Q V E+L +++ D+D DG + + EF ++K Sbjct: 123 QACEEFGVEDVRIEEL-------MRDVDQDNDGRIDYNEFVAMMQK 161 >5JN2-A nrPDB Length = 525 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 9/73 (12%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-VTEEQLENIADRTVQEADEDGDGA 171 R +L AF+++D D GKIS E+ + GV V E +++ + E D++ DG Sbjct: 458 RERLERAFRMFDSDNSGKISSTELATIF----GVSDVDSETWKSV----LSEVDKNNDGE 509 Query: 172 VSFVEFTKSLEKM 184 V F EF + L K+ Sbjct: 510 VDFDEFQQMLLKL 522 >3QRX-A nrPDB Length = 169 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 38/166 (22%), Positives = 71/166 (42%), Gaps = 25/166 (15%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGSQR 77 G ++ + F D + G + +L+ + AL P + I I DGS Sbjct: 21 GLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGT 80 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +DF F+ ++ D R ++ AF+L+D D G I+ ++ Sbjct: 81 IDFEEFLTMMTAKMGERD----------------SREEILKAFRLFDDDNSGTITIKDLR 124 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 +V + + G +TEE+L+ + + EAD + D + EF + ++K Sbjct: 125 RVAKEL-GENLTEEELQEM----IAEADRNDDNEIDEDEFIRIMKK 165 >2D8N-A nrPDB Length = 207 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 31/44 (70%), Gaps = 1/44 (2%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIAD 158 KL +AF LYD+D +G IS++E+L+++ + + +T E ++ + D Sbjct: 108 KLEWAFSLYDVDGNGTISKNEVLEIV-MAIFKMITPEDVKLLPD 150 >5B7X-A nrPDB Length = 156 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 63/131 (48%), Gaps = 13/131 (9%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 A+ ++ F DR+ G ++D++Q+G L + LG E + G Sbjct: 10 ANTQKIRDCFNFYDRDYDG---KIDVKQLGTL-IRSLGCAPTEDEVNSYIKEFAIEGETF 65 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG 145 + F + + ++ KP ++R KL AF+++D D+DGKI ++ L VG Sbjct: 66 QIEQFELIME-----REQSKP---DTREIKLRKAFEVFDQDKDGKIKASDLAHNLT-TVG 116 Query: 146 VQVTEEQLENI 156 ++T+E++E + Sbjct: 117 DKMTKEEVEKV 127 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 107 EPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL 153 E N+ K+ F YD D DGKI ++ ++R + G TE+++ Sbjct: 6 EAPNANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSL-GCAPTEDEV 51 >3PM8-A nrPDB Length = 197 Score = 35.8 bits (81), Expect = 0.014, Method: Compositional matrix adjust. Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 26/159 (16%) Query: 30 RLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 L + F ALD + G LS + L++IG + P +++ + S ++ + F+ Sbjct: 58 NLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLA 117 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG 145 D +T K+ + F+ +D+D +GKIS E L+ + G Sbjct: 118 ATI--------DKQTYLKKEVCLI---------PFKFFDIDGNGKISVEE----LKRIFG 156 Query: 146 VQVTEEQLENIA-DRTVQEADEDGDGAVSFVEFTKSLEK 183 E L + A D +QE D +GDG + F EF + K Sbjct: 157 RDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 195 >2LC5-A nrPDB Length = 151 Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust. Identities = 30/126 (23%), Positives = 62/126 (49%), Gaps = 21/126 (16%) Query: 35 FRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRVDFPGFVRVLAHF 90 F+ D++ L+ +L + AL NP +I ++ + D S + D F+ ++ + Sbjct: 20 FQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNSGKFDQETFLTIMLEY 79 Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 D T+D KK AF+++D +++G IS E+ VL + G ++TE Sbjct: 80 GQEVDS---TEDIKK-------------AFEIFDKEKNGYISASELKHVLTTL-GEKLTE 122 Query: 151 EQLENI 156 ++++++ Sbjct: 123 QEVDDL 128 Score = 30.4 bits (67), Expect = 0.51, Method: Compositional matrix adjust. Identities = 18/52 (34%), Positives = 31/52 (59%), Gaps = 5/52 (9%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 AFQL+D D D K++ E+ V+R + G T++++ I V++ D+D G Sbjct: 19 AFQLFDKDNDNKLTAEELGTVMRAL-GANPTKQKISEI----VKDYDKDNSG 65 >1ZMZ-A nrPDB Length = 98 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 40/73 (54%), Gaps = 5/73 (6%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 KPE ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E Sbjct: 22 KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL-GFEPKKEEIKKM----ISEI 76 Query: 165 DEDGDGAVSFVEF 177 D++G G ++F +F Sbjct: 77 DKEGTGKMNFGDF 89 >1F55-A nrPDB Length = 77 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 5/59 (8%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF L+D D +G IS E+ V+R +G+ +E ++ ++ + E D DG+ + F EF Sbjct: 15 AFALFDKDNNGSISSSELATVMR-SLGLSPSEAEVNDL----MNEIDVDGNHQIEFSEF 68 >2AMI-A nrPDB Length = 96 Score = 35.0 bits (79), Expect = 0.019, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 36/66 (54%), Gaps = 5/66 (7%) Query: 112 RRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGA 171 ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E D+DG G Sbjct: 28 QKQEIREAFDLFDTDGSGTIDAKELKVAMRAL-GFEPKKEEIKKM----ISEIDKDGSGT 82 Query: 172 VSFVEF 177 + F EF Sbjct: 83 IDFEEF 88 >1S6I-A nrPDB Length = 188 Score = 34.7 bits (78), Expect = 0.030, Method: Compositional matrix adjust. Identities = 34/166 (20%), Positives = 68/166 (40%), Gaps = 30/166 (18%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLS----RMDLQQIGALAVNPLGDRIIESFFPDGSQRV 78 S+ + L F+ +D + G ++ + L+++G+ + ++++ D S + Sbjct: 4 LSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTI 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 D+ F+ H +E R L AF +D D G I+ E+ Q Sbjct: 64 DYGEFIAATVHLNKLE-----------------REENLVSAFSYFDKDGSGYITLDEIQQ 106 Query: 139 VLRLMVGVQVTEEQLENI-ADRTVQEADEDGDGAVSFVEFTKSLEK 183 + + L++I D ++E D+D DG + + EF + K Sbjct: 107 ACK--------DFGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 >2B1U-A nrPDB Length = 71 Score = 34.3 bits (77), Expect = 0.033, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 39/68 (57%), Gaps = 5/68 (7%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 L AF+ +D D DG I+ E+ + + +G + +E+L D ++EAD D DG V++ Sbjct: 8 LQVAFRAFDQDGDGHITVDELRRAM-AGLGQPLPQEEL----DAMIREADVDQDGRVNYE 62 Query: 176 EFTKSLEK 183 EF + L + Sbjct: 63 EFARMLAQ 70 Score = 26.9 bits (58), Expect = 5.7, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG----DRIIESFFPDGSQRVD 79 ++A L L FRA D++ G+++ +L++ A PL D +I D RV+ Sbjct: 1 ARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVN 60 Query: 80 FPGFVRVLAH 89 + F R+LA Sbjct: 61 YEEFARMLAQ 70 >3TZ1-A nrPDB Length = 74 Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 7/71 (9%) Query: 107 EPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADE 166 E L+ R +L AF++ D ++ G I + +L+ + G ++TE+++EN+ + E D Sbjct: 2 EDLDER--ELKEAFRVLDKEKKGVIKVDVLRWILKSL-GDELTEDEIENM----IAETDT 54 Query: 167 DGDGAVSFVEF 177 DG G V + EF Sbjct: 55 DGSGTVDYEEF 65 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 12/61 (19%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFF--------PDGSQRVDFPG 82 L FR LD+ KKG + L+ I + LGD + E DGS VD+ Sbjct: 9 LKEAFRVLDKEKKGVIKVDVLRWI----LKSLGDELTEDEIENMIAETDTDGSGTVDYEE 64 Query: 83 F 83 F Sbjct: 65 F 65 >2VRG-A nrPDB Length = 124 Score = 34.3 bits (77), Expect = 0.040, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 21/93 (22%) Query: 104 KKPEP-LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------------VT 149 KPE ++ + +LHY F+++D D + +L L L + ++ Sbjct: 39 NKPEAEMSPQELQLHY-FKMHDYDGNN------LLDGLELSTAITHVHKEEGSEQAPLMS 91 Query: 150 EEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 E++L NI D +++ D++ DG + + EF KSL+ Sbjct: 92 EDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 124 >3LCP-C nrPDB Length = 93 Score = 33.9 bits (76), Expect = 0.041, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 21/93 (22%) Query: 104 KKPEP-LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------------VT 149 KPE ++ + +LHY F+++D D + +L L L + ++ Sbjct: 8 NKPEAEMSPQELQLHY-FKMHDYDGNN------LLDGLELSTAITHVHKEEGSEQAPLMS 60 Query: 150 EEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 E++L NI D +++ D++ DG + + EF KSL+ Sbjct: 61 EDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 93 >3A4U-B nrPDB Length = 143 Score = 33.9 bits (76), Expect = 0.044, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 21/93 (22%) Query: 104 KKPEP-LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------------VT 149 KPE ++ + +LHY F+++D D + +L L L + ++ Sbjct: 58 NKPEAEMSPQELQLHY-FKMHDYDGNN------LLDGLELSTAITHVHKEEGSEQAPLMS 110 Query: 150 EEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 E++L NI D +++ D++ DG + + EF KSL+ Sbjct: 111 EDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 143 >2GGZ-A nrPDB Length = 211 Score = 33.9 bits (76), Expect = 0.049, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 7/73 (9%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL----ENIADRTVQEADEDGDG 170 KL + F+LYD D +G I ++E+L + + VQ Q E + + D + DG Sbjct: 94 KLKWYFKLYDADGNGSIDKNELLD---MFMAVQALNGQQTLSPEEFINLVFHKIDINNDG 150 Query: 171 AVSFVEFTKSLEK 183 ++ EF + K Sbjct: 151 ELTLEEFINGMAK 163 >4MSP-A nrPDB Length = 200 Score = 33.9 bits (76), Expect = 0.051, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 117 HYAFQLYDLDRDGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAVS 173 H +FQ DL+ D K+S+ E+ L+ G V E + + + + DED DG +S Sbjct: 130 HESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFIS 189 Query: 174 FVEFT 178 EFT Sbjct: 190 AREFT 194 >1TIZ-A nrPDB Length = 67 Score = 33.9 bits (76), Expect = 0.052, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 5/66 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 F+ +D ++DGK+S E +V L T+E + + +E D DG+G ++ EFT Sbjct: 6 VFEKFDKNKDGKLSLDEFREV-ALAFSPYFTQEDIV----KFFEEIDVDGNGELNADEFT 60 Query: 179 KSLEKM 184 +EKM Sbjct: 61 SCIEKM 66 >2BL0-C nrPDB Length = 142 Score = 33.1 bits (74), Expect = 0.083, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF+L+D +R G I++ E LQ + GV+V + EAD G+G + F EF Sbjct: 11 AFELFDSERTGFITK-EGLQTVLKQFGVRVEPAAFNEM----FNEADATGNGKIQFPEF 64 >1JFJ-A nrPDB Length = 134 Score = 33.1 bits (74), Expect = 0.083, Method: Compositional matrix adjust. Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 27/147 (18%) Query: 35 FRALDRNKKGYLSRMDLQQIG----ALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHF 90 F+ +D N G +S +++ A+ L I +S DG+ +D F + Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSI 65 Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 + + L+ + L ++L D+D DGK+++ E+ + + Sbjct: 66 QG--------------QDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFK--------K 103 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEF 177 +E +A++ V +AD +GDG ++ EF Sbjct: 104 HGIEKVAEQ-VMKADANGDGYITLEEF 129 >2JNX-A nrPDB Length = 134 Score = 33.1 bits (74), Expect = 0.085, Method: Compositional matrix adjust. Identities = 31/147 (21%), Positives = 62/147 (42%), Gaps = 27/147 (18%) Query: 35 FRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP----DGSQRVDFPGFVRVLAHF 90 F+ LD N G +S +++ + +++++ F DG+ +D F + A Sbjct: 6 FKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAAV 65 Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 K + L+ + L ++L D D DGK+++ E+ + Sbjct: 66 --------------KEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKF------- 104 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEF 177 E + D+ + +AD +GDG ++ EF Sbjct: 105 -GYEKVVDQ-IMKADANGDGYITLEEF 129 >4YGB-B nrPDB Length = 104 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 25/35 (71%) Query: 148 VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 ++E++L NI D +++ D++ DG + + EF KSL+ Sbjct: 70 MSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 104 >2HF5-A nrPDB Length = 68 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 16/69 (23%) Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 DG+ +DFP F+ ++A R ++D D+E + + AF+++D D +G I Sbjct: 12 ADGNGTIDFPEFLTMMA--RKMKDTDSEEE--------------IREAFRVFDKDGNGYI 55 Query: 132 SRHEMLQVL 140 S E+ V+ Sbjct: 56 SAAELRHVM 64 >2K2A-A nrPDB Length = 70 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 + +L AF+LYD + +G IS M ++L ++ E D + E D DG G V Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREIL-----AELDETLSSEDLDAMIDEIDADGSGTV 56 Query: 173 SFVEF 177 F EF Sbjct: 57 DFEEF 61 Score = 30.4 bits (67), Expect = 0.52, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG----DRIIESFFPDGSQRVDFPGFVR 85 L FR D+ GY+S +++I A L D +I+ DGS VDF F+ Sbjct: 4 ELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMG 63 Query: 86 VLA 88 V+ Sbjct: 64 VMT 66 >5E37-A nrPDB Length = 356 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 4/71 (5%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV---TEEQL-ENIADRTVQEADE 166 ++ +L F++ D+D +G I R E+ +L M +V ++ L E+ +R +++ D Sbjct: 26 AKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDV 85 Query: 167 DGDGAVSFVEF 177 + DG +SF EF Sbjct: 86 NKDGVISFEEF 96 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 16/66 (24%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 ++L + YD+++DG IS E Q++ + ++ T + E+ + D+ G+G + Sbjct: 74 DELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYES----AFKAVDKSGNGTIG 129 Query: 174 FVEFTK 179 E +K Sbjct: 130 ATELSK 135 Score = 27.3 bits (59), Expect = 4.4, Method: Compositional matrix adjust. Identities = 14/64 (21%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----IIESFFPDGSQRVDF 80 + +L F+A+D++ G + +L ++ A NP+ +++ + D S +++F Sbjct: 107 EGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEF 166 Query: 81 PGFV 84 P F+ Sbjct: 167 PEFL 170 >1C7W-A nrPDB Length = 81 Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 6/66 (9%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENI-ADRTVQEADEDGDGAVSFVEF 177 AF+++D + DG I E +++ +V EE L + + ++EADEDG+G + EF Sbjct: 13 AFKVFDANGDGVIDFDEFKFIMQ-----KVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 178 TKSLEK 183 ++K Sbjct: 68 MDLIKK 73 >1OQP-A nrPDB Length = 77 Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 41/71 (57%), Gaps = 5/71 (7%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 R ++ AF+L+D D G I+ ++ +V + + G +TEE+L+ + + EAD + D + Sbjct: 8 REEILKAFRLFDDDNSGTITIKDLRRVAKEL-GENLTEEELQEM----IAEADRNDDNEI 62 Query: 173 SFVEFTKSLEK 183 EF + ++K Sbjct: 63 DEDEFIRIMKK 73 >2I18-A nrPDB Length = 64 Score = 31.6 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 9/62 (14%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 L ++L D+D DGK+++ E+ + + +E +A++ V +AD +GDG ++ Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFK--------KHGIEKVAEQ-VMKADANGDGYITLE 57 Query: 176 EF 177 EF Sbjct: 58 EF 59 >5I2L-A nrPDB Length = 120 Score = 31.6 bits (70), Expect = 0.24, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 F+ YD RDG I E L+++ +G T L+N+ ++E DED D +SF EF Sbjct: 37 FKQYDAGRDGFIDLME-LKLMMEKLGAPQTHLGLKNM----IKEVDEDFDSKLSFREF 89 >5Z1Q-A nrPDB Length = 95 Score = 31.2 bits (69), Expect = 0.27, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 8/80 (10%) Query: 101 QDPKK---PEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIA 157 Q PKK E ++ ++ AF L+D ++ G I HE+ +R + G V + ++ + Sbjct: 11 QPPKKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRAL-GFDVKKPEILEL- 68 Query: 158 DRTVQEADEDGDGAVSFVEF 177 + E D +G+G + F +F Sbjct: 69 ---MNEYDREGNGYIGFDDF 85 >4WPX-A nrPDB Length = 177 Score = 31.2 bits (69), Expect = 0.30, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 5/67 (7%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 R++L AF+L+D+D G I+ ++ +V + VG + + ++ + ++E D +G G V Sbjct: 110 RDELRRAFRLFDVDGKGMITEDDLRKVCQ-QVGNNIPDADIQAM----IEEFDSNGKGGV 164 Query: 173 SFVEFTK 179 EF + Sbjct: 165 DEDEFLR 171 Score = 26.2 bits (56), Expect = 9.5, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQ 152 + ++ ++ AF+L+D ++DG +S E VLR + G + ++Q Sbjct: 22 DEQKTRISEAFELFDSNKDGLLSYEEFRFVLRAL-GFDLPKQQ 63 >3DTP-E nrPDB Length = 196 Score = 31.2 bits (69), Expect = 0.30, Method: Compositional matrix adjust. Identities = 34/165 (20%), Positives = 74/165 (44%), Gaps = 30/165 (18%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRV 78 F+Q + F+ +D++K G++S+ D++ +G L ++ ++S + + Sbjct: 51 FTQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCT----EQELDSMVAEAPGPI 106 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 +F F+ + DE+ + + AF L+D + DGK + E L+ Sbjct: 107 NFTMFLTIFGDRIAGTDEE----------------DVIVNAFNLFD-EGDGKC-KEETLK 148 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 G + +++++ D+ + EA DG+G + +F + L K Sbjct: 149 RSLTTWGEKFSQDEV----DQALSEAPIDGNGLIDIKKFAQILTK 189 >2IM5-A nrPDB Length = 394 Score = 30.8 bits (68), Expect = 0.35, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 7/57 (12%) Query: 11 IPDGDSIRRETGFSQASLL-RLHHRFRALDRNKKGY------LSRMDLQQIGALAVN 60 I D D + TG++ A L R + FR +DRN++G+ L R +++ + AL++ Sbjct: 7 ILDTDLYKFTTGYAYAKLFPRAYGEFRFIDRNRQGFTEEFAELVRGEIRAMAALSLT 63 >2BL0-B nrPDB Length = 145 Score = 30.4 bits (67), Expect = 0.51, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 73/160 (45%), Gaps = 27/160 (16%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 AS ++ F+ D++ G +S ++++G+ A+ LG P ++ G + Sbjct: 2 ASADQIQECFQIFDKDNDGKVS---IEELGS-ALRSLGKN------PTNAELNTIKGQLN 51 Query: 86 V----LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 LA F+ V + +T + E L+ AF+ D + +G I E+ Q+L Sbjct: 52 AKEFDLATFKTVYRKPIKTPTEQSKEMLD--------AFRALDKEGNGTIQEAELRQLL- 102 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 L +G +T ++E + ++E GDGA+++ F L Sbjct: 103 LNLGDALTSSEVEEL----MKEVSVSGDGAINYESFVDML 138 >2JOJ-A nrPDB Length = 77 Score = 30.0 bits (66), Expect = 0.60, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 5/66 (7%) Query: 112 RRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGA 171 ++ ++ AF L+D ++ G I HE+ +R + G V + ++ + + E D +G+G Sbjct: 5 QKQEIKEAFDLFDTNKTGSIDYHELKVAMRAL-GFDVKKPEILEL----MNEYDREGNGY 59 Query: 172 VSFVEF 177 + F +F Sbjct: 60 IGFDDF 65 >1QX2-A nrPDB Length = 76 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 19/27 (70%) Query: 158 DRTVQEADEDGDGAVSFVEFTKSLEKM 184 D ++E D++GDG VSF EF ++K+ Sbjct: 48 DEMIEEVDKNGDGEVSFEEFLVMMKKI 74 >3I5H-B nrPDB Length = 153 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 29/139 (20%), Positives = 59/139 (42%), Gaps = 19/139 (13%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPDGSQR 77 R SQ + L F +D+++ G++ DL+ + +L P D + + + + Sbjct: 6 RRVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDE-LNAMLKECPGQ 64 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 ++F F+ + E DP+ + L AF ++D D G I + Sbjct: 65 LNFTAFLTLFG-------EKVSGTDPE---------DALRNAFSMFDEDGQGFIPEDYLK 108 Query: 138 QVLRLMVGVQVTEEQLENI 156 +L M G ++E+++N+ Sbjct: 109 DLLENM-GDNFSKEEIKNV 126 >1ZFS-A nrPDB Length = 93 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 29/49 (59%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 K+S+ E+ +L+ + + ++ + D+ ++E DE+GDG V F EF Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFV 75 >2PMY-A nrPDB Length = 91 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 7/67 (10%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L F D +R G++ R E L ++V E + Q D D DGA++F Sbjct: 28 RLRSVFAACDANRSGRLEREEFRA---LCTELRVRPADAEAV----FQRLDADRDGAITF 80 Query: 175 VEFTKSL 181 EF + Sbjct: 81 QEFARGF 87 >4MN0-A nrPDB Length = 208 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVL-RLMVGVQVTEEQLENIAD 158 ++L+ F +DLD DGK+ E+L R+ V T+EQ+E + D Sbjct: 36 SRLYKRFDTFDLDSDGKMEMDEVLYWPDRMRQLVNATDEQVEKMRD 81 >5JOJ-A nrPDB Length = 97 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF D D +G IS +E+ + + + + ++ I + + D D DG +SF Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC-LPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 175 VEFTK---SLEKMDVEQ 188 EF K L+ DV + Sbjct: 72 DEFIKIFHGLKSTDVAK 88 >5JOL-A nrPDB Length = 82 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF D D +G IS +E+ + + + + ++ I + + D D DG +SF Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC-LPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 175 VEFTK 179 EF K Sbjct: 72 DEFIK 76 >2L0P-A nrPDB Length = 94 Score = 27.7 bits (60), Expect = 3.0, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 30/49 (61%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 K+S+ E+ ++L+ + + ++ + D+ ++E DE+GDG V F E+ Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYV 76 >2ME6-A nrPDB Length = 71 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 5/44 (11%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG 55 P G S RR T F+ LL L F K YLS + QI Sbjct: 3 PGGKSRRRRTAFTSEQLLELEKEFHC-----KKYLSLTERSQIA 41 >1QLS-A nrPDB Length = 99 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 127 RDG---KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 RDG KIS+ E L + + ++ + DR +++ D D DG + F EF Sbjct: 25 RDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEF 78 >3AKA-A nrPDB Length = 166 Score = 27.7 bits (60), Expect = 3.3, Method: Compositional matrix adjust. Identities = 41/174 (23%), Positives = 63/174 (36%), Gaps = 38/174 (21%) Query: 30 RLHHRFRALDRNKKGYLSRMD--------LQQIGALAVNPLGDRI---IESFFP------ 72 R+ RF D++ G++ R D L + G A + G + E+ + Sbjct: 5 RIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIA 64 Query: 73 --DGSQRVDFPGFVR-VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDG 129 DG QR+ FV + R D E P LH A + D D DG Sbjct: 65 DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPF-----------LHAALGVADTDGDG 113 Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 ++ + + L GV E++A + D DGDG V E + + Sbjct: 114 AVTVADTARAL-TAFGVP------EDLARQAAAALDTDGDGKVGETEIVPAFAR 160 >5VP3-A nrPDB Length = 206 Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVL-RLMVGVQVTEEQLENI 156 +L+ F +DLD DGK++ E++ R+ V T+EQ+E + Sbjct: 35 RLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKM 77 >3JBH-C nrPDB Length = 156 Score = 27.3 bits (59), Expect = 4.6, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 ++YD +G + E+ VL L +G ++T+ + E I ++ DED DG + + F Sbjct: 89 GLKVYDKAENGTMLAAELAHVL-LSLGERLTDIECEEI----MRVCDEDDDGFLKYEPFV 143 Query: 179 KSL 181 K++ Sbjct: 144 KTI 146 >1CB1-A nrPDB Length = 78 Score = 26.9 bits (58), Expect = 5.8, Method: Compositional matrix adjust. Identities = 12/20 (60%), Positives = 14/20 (70%) Query: 158 DRTVQEADEDGDGAVSFVEF 177 D QE D++GDG VSF EF Sbjct: 50 DDLFQELDKNGDGEVSFEEF 69 >5XOP-A nrPDB Length = 66 Score = 26.9 bits (58), Expect = 5.9, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+ D++ DG +S E+ + ++ EQL + +++ D+DGDG + F EF K Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIK--NEQLLQLIFKSI---DKDGDGFIDFEEFAK 60 >3PAT-A nrPDB Length = 110 Score = 26.2 bits (56), Expect = 8.5, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMV--GVQVTEEQLENIADRTVQEADEDGDGA 171 N + F+ D D G I E+ VL+ G +T+ + + ++ AD+DGDG Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAF----LKAADKDGDGK 97 Query: 172 VSFVEF 177 + EF Sbjct: 98 IGIDEF 103 >1RTP-1 nrPDB Length = 109 Score = 26.2 bits (56), Expect = 8.8, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 4/60 (6%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA-DEDGDGAVSFVEFT 178 F + D D+ G I E+ +L+ G L +T+ A D+DGDG + EF+ Sbjct: 47 FHILDKDKSGFIEEDELGSILK---GFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFS 103 >1G33-A nrPDB Length = 73 Score = 26.2 bits (56), Expect = 9.9, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 4/60 (6%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA-DEDGDGAVSFVEFT 178 F + D D+ G I E+ +L+ G L +T+ A D+DGDG + EF+ Sbjct: 11 FHILDKDKSGFIEEDELGSILK---GFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFS 67 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2BEC-A nrPDB 236 5e-63 2E30-A nrPDB 197 3e-51 4OY4-A nrPDB 167 3e-42 4IL1-A nrPDB 166 9e-42 3U0K-A nrPDB 156 7e-39 3EK4-A nrPDB 154 3e-38 4I2Y-A nrPDB 153 4e-38 5UKG-A nrPDB 152 8e-38 4ORC-B nrPDB 151 3e-37 5B8I-B nrPDB 144 2e-35 3WFN-B nrPDB 136 7e-33 2N6A-A nrPDB 135 2e-32 6O20-F nrPDB 131 2e-31 2F2P-A nrPDB 130 3e-31 4E53-A nrPDB 128 1e-30 2JUL-A nrPDB 127 2e-30 5T7C-A nrPDB 127 3e-30 6HCS-A nrPDB 126 7e-30 5I0I-E nrPDB 123 4e-29 1S6C-A nrPDB 123 4e-29 1BJF-A nrPDB 122 1e-28 1CLM-A nrPDB 122 1e-28 1S1E-A nrPDB 122 1e-28 5A2H-A nrPDB 119 7e-28 3DD4-A nrPDB 119 1e-27 5M6C-E nrPDB 118 2e-27 1GGZ-A nrPDB 117 3e-27 2LAP-A nrPDB 117 4e-27 2L2E-A nrPDB 117 4e-27 3HZT-A nrPDB 116 8e-27 2ZFD-A nrPDB 113 5e-26 4JWQ-A nrPDB 113 6e-26 2L1W-A nrPDB 112 8e-26 3O4Y-A nrPDB 112 9e-26 3K21-A nrPDB 110 3e-25 2LCP-A nrPDB 110 4e-25 1UHN-A nrPDB 109 7e-25 2JU0-A nrPDB 107 2e-24 1V1G-A nrPDB 107 3e-24 2R2I-A nrPDB 106 5e-24 1TOP-A nrPDB 106 6e-24 2TN4-A nrPDB 104 3e-23 3KHE-A nrPDB 102 7e-23 6EPA-A nrPDB 101 2e-22 2LMV-A nrPDB 101 2e-22 2GGM-A nrPDB 100 5e-22 2NA0-A nrPDB 100 6e-22 5D43-A nrPDB 99 1e-21 1JBA-A nrPDB 98 2e-21 3J04-B nrPDB 97 5e-21 3KF9-A nrPDB 97 6e-21 3NCG-A nrPDB 96 1e-20 2OBH-A nrPDB 91 2e-19 2JNF-A nrPDB 89 1e-18 1DGU-A nrPDB 89 1e-18 2LM5-A nrPDB 87 3e-18 1DTL-A nrPDB 83 7e-17 5YPX-A nrPDB 83 8e-17 2E6W-A nrPDB 82 2e-16 5ZOR-A nrPDB 80 5e-16 4N5X-A nrPDB 80 5e-16 4ZCV-A nrPDB 80 6e-16 5H7D-E nrPDB 76 9e-15 2KN2-A nrPDB 75 2e-14 1FW4-A nrPDB 74 5e-14 5COC-A nrPDB 72 2e-13 2K7C-A nrPDB 70 6e-13 2ROB-A nrPDB 70 7e-13 2RO9-A nrPDB 70 8e-13 2I08-A nrPDB 67 4e-12 4Q57-A nrPDB 67 5e-12 2RO8-A nrPDB 66 1e-11 3IFK-A nrPDB 66 2e-11 6IIE-A nrPDB 64 4e-11 2KSZ-A nrPDB 61 3e-10 2N7L-C nrPDB 60 5e-10 5OTJ-D nrPDB 60 6e-10 1TRF-A nrPDB 60 8e-10 1M39-A nrPDB 59 9e-10 1TNP-A nrPDB 59 1e-09 5VLN-A nrPDB 59 1e-09 2K2I-A nrPDB 58 3e-09 2OPO-A nrPDB 55 2e-08 Sequences not found previously or not previously below threshold: 2LHI-A nrPDB 103 6e-23 3QRX-A nrPDB 100 5e-22 4DS7-A nrPDB 99 2e-21 1LKJ-A nrPDB 97 4e-21 5JN2-A nrPDB 92 2e-19 3Q5I-A nrPDB 89 8e-19 4MVF-A nrPDB 89 1e-18 2I94-A nrPDB 89 1e-18 2AAO-A nrPDB 89 1e-18 3LIJ-A nrPDB 88 2e-18 4YZB-A nrPDB 88 2e-18 2M29-A nrPDB 88 3e-18 4RGJ-A nrPDB 87 4e-18 2LHH-A nrPDB 87 5e-18 2GGZ-A nrPDB 86 9e-18 4WPX-A nrPDB 83 8e-17 3PM8-A nrPDB 83 9e-17 1S6I-A nrPDB 83 9e-17 2D8N-A nrPDB 82 1e-16 3L19-A nrPDB 82 2e-16 3FWC-A nrPDB 81 3e-16 2LC5-A nrPDB 77 5e-15 5MWC-D nrPDB 76 7e-15 2BL0-B nrPDB 72 2e-13 3JAX-C nrPDB 72 2e-13 1W7I-B nrPDB 71 2e-13 2KZ2-A nrPDB 71 4e-13 3DTP-E nrPDB 70 8e-13 2LV7-A nrPDB 69 9e-13 2M5E-A nrPDB 69 2e-12 5E37-A nrPDB 68 3e-12 2JNX-A nrPDB 66 8e-12 2BL0-C nrPDB 66 1e-11 5TBY-E nrPDB 64 3e-11 6FSA-D nrPDB 64 4e-11 2HF5-A nrPDB 63 8e-11 3I5H-B nrPDB 63 9e-11 1I84-U nrPDB 63 1e-10 1JFJ-A nrPDB 62 1e-10 5TBY-C nrPDB 62 1e-10 5H53-C nrPDB 62 2e-10 2B1U-A nrPDB 61 2e-10 2AMI-A nrPDB 61 2e-10 1O1A-B nrPDB 61 3e-10 1GGW-A nrPDB 61 3e-10 2G9B-A nrPDB 60 8e-10 2K2A-A nrPDB 60 8e-10 1SR6-C nrPDB 59 9e-10 3AAJ-A nrPDB 59 1e-09 1B7T-Y nrPDB 59 2e-09 2OS8-B nrPDB 58 2e-09 1JC2-A nrPDB 58 2e-09 1N2D-A nrPDB 58 3e-09 3E3R-A nrPDB 58 3e-09 1JF0-A nrPDB 58 3e-09 5H53-B nrPDB 57 6e-09 2W4G-C nrPDB 57 7e-09 1F55-A nrPDB 56 8e-09 2LVK-A nrPDB 56 1e-08 2M97-A nrPDB 56 1e-08 4GJF-A nrPDB 56 1e-08 1DFK-Y nrPDB 55 1e-08 1H4B-A nrPDB 55 2e-08 3I5I-C nrPDB 55 2e-08 1OQP-A nrPDB 55 3e-08 3KPX-A nrPDB 55 3e-08 1S36-A nrPDB 54 3e-08 1ZMZ-A nrPDB 54 3e-08 5B7X-A nrPDB 54 4e-08 2M8U-A nrPDB 54 4e-08 3TS5-B nrPDB 53 7e-08 1YX7-A nrPDB 53 8e-08 2EC6-B nrPDB 52 1e-07 5JOJ-A nrPDB 52 1e-07 5JOL-A nrPDB 52 1e-07 1C7W-A nrPDB 52 2e-07 2K7B-A nrPDB 52 2e-07 1OZS-A nrPDB 51 3e-07 1Q80-A nrPDB 51 4e-07 3JBH-C nrPDB 50 6e-07 2Q4U-A nrPDB 50 7e-07 1QX2-A nrPDB 49 1e-06 1SJJ-A nrPDB 49 2e-06 5Z1Q-A nrPDB 48 2e-06 3TZ1-A nrPDB 48 3e-06 1Y1X-A nrPDB 47 4e-06 5XND-A nrPDB 47 5e-06 3MSE-B nrPDB 47 6e-06 3AKA-A nrPDB 47 7e-06 4NQG-A nrPDB 46 8e-06 3SIA-A nrPDB 46 8e-06 2JOJ-A nrPDB 46 8e-06 2N8Y-A nrPDB 46 9e-06 4D1E-A nrPDB 46 1e-05 2KYF-A nrPDB 46 1e-05 5ZGM-A nrPDB 45 2e-05 1ZFS-A nrPDB 45 2e-05 2VRG-A nrPDB 45 2e-05 3LCP-C nrPDB 45 2e-05 1UHK-A nrPDB 45 2e-05 3A4U-B nrPDB 45 3e-05 5PAL-A nrPDB 44 4e-05 1SL8-A nrPDB 44 4e-05 5I2L-A nrPDB 44 5e-05 5ZH6-A nrPDB 43 8e-05 3PAT-A nrPDB 43 9e-05 1S6J-A nrPDB 43 9e-05 4OCI-A nrPDB 43 1e-04 2L0P-A nrPDB 42 1e-04 5E1J-A nrPDB 42 1e-04 5XOP-A nrPDB 42 1e-04 2LVV-A nrPDB 42 1e-04 4YGB-B nrPDB 42 1e-04 2M1U-A nrPDB 42 2e-04 1A75-A nrPDB 42 2e-04 1QXP-A nrPDB 42 2e-04 1NYA-A nrPDB 42 2e-04 2L50-A nrPDB 42 2e-04 2KQY-A nrPDB 41 2e-04 5CPV-A nrPDB 41 3e-04 4P5X-A nrPDB 41 3e-04 2PMY-A nrPDB 41 3e-04 1RTP-1 nrPDB 41 3e-04 5VE9-A nrPDB 41 4e-04 1IJ5-A nrPDB 41 4e-04 1TIZ-A nrPDB 40 4e-04 1JUO-A nrPDB 40 5e-04 4PAL-A nrPDB 40 5e-04 2WCE-A nrPDB 40 7e-04 1BU3-A nrPDB 40 7e-04 1G33-A nrPDB 40 7e-04 2NCO-A nrPDB 40 7e-04 1RK9-A nrPDB 40 8e-04 2SAS-A nrPDB 40 9e-04 2LUC-A nrPDB 40 9e-04 4MSP-A nrPDB 39 0.001 2I18-A nrPDB 39 0.001 5MRA-A nrPDB 39 0.001 1KFU-L nrPDB 39 0.001 1TTX-A nrPDB 39 0.001 1QLS-A nrPDB 39 0.001 2M7M-A nrPDB 39 0.001 1KFX-S nrPDB 39 0.001 2NLN-A nrPDB 39 0.002 3DF0-A nrPDB 39 0.002 4OKH-A nrPDB 39 0.002 2FCE-A nrPDB 38 0.002 1NSH-A nrPDB 38 0.002 5VT9-A nrPDB 38 0.003 5HYD-A nrPDB 38 0.003 4I5L-B nrPDB 38 0.003 1CB1-A nrPDB 38 0.003 1GJY-A nrPDB 38 0.003 2HPS-A nrPDB 37 0.004 3CS1-A nrPDB 37 0.005 1BOD-A nrPDB 37 0.007 6MI5-X nrPDB 37 0.007 5VP3-A nrPDB 37 0.007 4L9M-A nrPDB 36 0.008 4MEW-A nrPDB 36 0.009 5CSF-A nrPDB 36 0.009 2KGR-A nrPDB 36 0.012 2M7L-A nrPDB 35 0.014 5W1A-B nrPDB 35 0.017 4I5K-A nrPDB 35 0.028 2MBX-A nrPDB 34 0.031 2Y5I-A nrPDB 34 0.032 1KQV-A nrPDB 34 0.039 6AGH-A nrPDB 34 0.052 4C0K-A nrPDB 34 0.058 4P5W-A nrPDB 34 0.060 2MJW-B nrPDB 33 0.076 1F4Q-A nrPDB 33 0.079 6EAZ-A nrPDB 33 0.081 4NSC-A nrPDB 33 0.081 1NUB-A nrPDB 33 0.085 2MA2-A nrPDB 33 0.096 1WY9-A nrPDB 32 0.12 5HLO-A nrPDB 32 0.14 3H4S-E nrPDB 32 0.15 6AGI-A nrPDB 32 0.16 3A8R-A nrPDB 32 0.17 3NSO-A nrPDB 32 0.18 6DS2-B nrPDB 31 0.28 1NP8-A nrPDB 31 0.31 4YBH-B nrPDB 31 0.38 2JXC-A nrPDB 30 0.54 6DU8-A nrPDB 30 0.60 2G2B-A nrPDB 30 0.66 4MN0-A nrPDB 30 0.71 1DJX-A nrPDB 30 0.74 5LPU-C nrPDB 30 0.75 6FFL-A nrPDB 30 0.81 1SRA-A nrPDB 30 0.81 5C5V-A nrPDB 30 0.85 2VTG-A nrPDB 30 0.89 4AOM-A nrPDB 30 0.90 2AUC-A nrPDB 30 0.94 3BOW-B nrPDB 29 0.98 5CUY-A nrPDB 29 0.99 4DUQ-A nrPDB 29 1.0 4CFQ-A nrPDB 29 1.1 2JQ6-A nrPDB 29 1.3 5X2G-A nrPDB 29 1.5 4GFT-A nrPDB 29 1.6 2KFH-A nrPDB 29 1.6 2D58-A nrPDB 29 1.7 1L9X-A nrPDB 29 1.7 2KHN-A nrPDB 29 1.8 5ES6-A nrPDB 29 2.0 5ZCR-A nrPDB 29 2.0 2JTT-A nrPDB 28 2.2 4DKN-A nrPDB 28 2.3 5ES8-A nrPDB 28 2.4 5MVF-A nrPDB 28 2.7 1SNL-A nrPDB 28 3.0 3VSL-A nrPDB 28 3.2 2JMM-A nrPDB 28 3.4 4JB3-A nrPDB 28 3.5 5CUU-A nrPDB 27 3.8 1C07-A nrPDB 27 4.5 4K00-A nrPDB 27 4.5 4PCW-A nrPDB 27 4.7 5NRM-B nrPDB 27 5.1 2XU0-A nrPDB 27 5.5 5ED8-A nrPDB 27 5.9 4CJ1-A nrPDB 27 6.7 4EAC-A nrPDB 27 7.4 5KU1-A nrPDB 26 8.8 >2BEC-A nrPDB Length = 202 Score = 236 bits (602), Expect = 5e-63, Method: Composition-based stats. Identities = 196/196 (100%), Positives = 196/196 (100%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN Sbjct: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 Query: 61 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF Sbjct: 61 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 Query: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS Sbjct: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 Query: 181 LEKMDVEQKMSIRILK 196 LEKMDVEQKMSIRILK Sbjct: 181 LEKMDVEQKMSIRILK 196 >2E30-A nrPDB Length = 195 Score = 197 bits (501), Expect = 3e-51, Method: Composition-based stats. Identities = 119/195 (61%), Positives = 155/195 (79%), Gaps = 1/195 (0%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MGSR+S + + I++ETGFS + + RL+ RF +LD+ + G LSR D Q+I LA+N Sbjct: 1 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN 60 Query: 61 PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 PLGDRII +FFP+G +V+F GF+R LAHFRP+ED + +++D PEPLNSR NKLH+AF Sbjct: 61 PLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNE-KSKDVNGPEPLNSRSNKLHFAF 119 Query: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 +LYDLD+D KISR E+LQVLR+MVGV +++EQL +IADRT+QEAD+DGD A+SF EF K Sbjct: 120 RLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKV 179 Query: 181 LEKMDVEQKMSIRIL 195 LEK+DVEQKMSIR L Sbjct: 180 LEKVDVEQKMSIRFL 194 >4OY4-A nrPDB Length = 415 Score = 167 bits (422), Expect = 3e-42, Method: Composition-based stats. Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 25/175 (14%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG + Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTI 71 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 72 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 115 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIR 193 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + +KM +R Sbjct: 116 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYVR 165 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 4/87 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 74 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 133 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVE 94 DG +V++ FV+++ E Sbjct: 134 READIDGDGQVNYEEFVQMMTAKLECE 160 >4IL1-A nrPDB Length = 823 Score = 166 bits (419), Expect = 9e-42, Method: Composition-based stats. Identities = 61/178 (34%), Positives = 96/178 (53%), Gaps = 16/178 (8%) Query: 17 IRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQ 76 + + F + RL RF+ LD + G LS + + L NPL R+I+ F DG+ Sbjct: 166 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNG 225 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 VDF F+ ++ F D+ KL +AF++YD+D+DG IS E+ Sbjct: 226 EVDFKEFIEGVSQFSVKGDK----------------EQKLRFAFRIYDMDKDGYISNGEL 269 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 QVL++MVG + + QL+ I D+T+ AD+DGDG +SF EF + +D+ +KM + + Sbjct: 270 FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 327 Score = 157 bits (398), Expect = 2e-39, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 65 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 108 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 109 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 146 Score = 85.2 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 39/185 (21%), Positives = 71/185 (38%), Gaps = 18/185 (9%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 67 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN-----KLHYAFQL 122 DG +V++ FV+++ + P + S + +L F+ Sbjct: 127 READIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKK 186 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 DLD G +S E + + E Q + R + D DG+G V F EF + + Sbjct: 187 LDLDNSGSLSVEEF---------MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVS 237 Query: 183 KMDVE 187 + V+ Sbjct: 238 QFSVK 242 Score = 78.2 bits (191), Expect = 2e-15, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 66 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 67 PEFLTMMARK 76 >3U0K-A nrPDB Length = 442 Score = 156 bits (393), Expect = 7e-39, Method: Composition-based stats. Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 33/181 (18%) Query: 13 DGDSIRRET--------GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG 63 +G ++++T ++ + F D++ G ++ +L + +L NP Sbjct: 280 NGAVMQKKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE 339 Query: 64 ---DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 +I DG +DFP F+ ++A D ++ AF Sbjct: 340 AELQDMINEVDADGDGTIDFPEFLIMMARKMKDTD----------------SEEEIREAF 383 Query: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 +++D D +G IS E+ V+ + G ++T+E+ D ++EAD DGDG V++ EF + Sbjct: 384 RVFDKDGNGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQM 438 Query: 181 L 181 + Sbjct: 439 M 439 Score = 80.5 bits (197), Expect = 4e-16, Method: Composition-based stats. Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 5/89 (5%) Query: 96 EDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLEN 155 + T+ +P + + + + AF L+D D DG I+ E+ V+R + G TE +L++ Sbjct: 286 KKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD 344 Query: 156 IADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + E D DGDG + F EF + + Sbjct: 345 ----MINEVDADGDGTIDFPEFLIMMARK 369 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 33/81 (40%), Gaps = 4/81 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ + S + FR D++ GY+S +L+ + L D +I Sbjct: 360 PEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 419 Query: 68 ESFFPDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 420 READIDGDGQVNYEEFVQMMT 440 >3EK4-A nrPDB Length = 451 Score = 154 bits (388), Expect = 3e-38, Method: Composition-based stats. Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 27/174 (15%) Query: 14 GDSIRRETG--FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRII 67 G + T ++ + F D++ G ++ +L + +L NP +I Sbjct: 296 GHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI 355 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 DG+ +DFP F+ ++A D ++ AF+++D D Sbjct: 356 NEVDADGNGTIDFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDG 399 Query: 128 DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 +G IS E+ V+ + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 400 NGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 448 Score = 80.2 bits (196), Expect = 6e-16, Method: Composition-based stats. Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 17/122 (13%) Query: 63 GDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 GD ++ G +DF +L H D T++ + AF L Sbjct: 274 GDTLVNRIELKG---IDFKEDGNILGHKLEYNTRDQLTEEQIA---------EFKEAFSL 321 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 +D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F EF + Sbjct: 322 FDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDFPEFLTMMA 376 Query: 183 KM 184 + Sbjct: 377 RK 378 Score = 50.9 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 369 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 428 Query: 68 ESFFPDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 429 READIDGDGQVNYEEFVQMMT 449 >4I2Y-A nrPDB Length = 421 Score = 153 bits (387), Expect = 4e-38, Method: Composition-based stats. Identities = 44/182 (24%), Positives = 83/182 (45%), Gaps = 33/182 (18%) Query: 12 PDGDSIRRETG--------FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPL 62 PDG ++++T ++ + F D++ G ++ +L + +L NP Sbjct: 258 PDGPVMQKKTMGWEATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPT 317 Query: 63 G---DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 +I DG DFP F+ ++A R + D D+E ++ A Sbjct: 318 EAELQDMINEVDADGDGTFDFPEFLTMMA--RKMNDTDSE--------------EEIREA 361 Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+++D D +G I E+ V+ + G ++T+E+ D ++ AD DGDG V++ EF + Sbjct: 362 FRVFDKDGNGYIGAAELRHVMTDL-GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQ 416 Query: 180 SL 181 + Sbjct: 417 MM 418 Score = 78.2 bits (191), Expect = 2e-15, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 5/93 (5%) Query: 92 PVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEE 151 PV + T + + + + + AF L+D D DG I+ E+ V+R + G TE Sbjct: 261 PVMQKKTMGWEATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEA 319 Query: 152 QLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +L++ + E D DGDG F EF + + Sbjct: 320 ELQD----MINEVDADGDGTFDFPEFLTMMARK 348 Score = 49.0 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 33/77 (42%), Gaps = 5/77 (6%) Query: 16 SIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGA-LAVNPLG---DRIIESFF 71 + R+ + + + FR D++ GY+ +L+ + L D +I Sbjct: 344 MMARKMNDTDSE-EEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVAD 402 Query: 72 PDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 403 IDGDGQVNYEEFVQMMT 419 >5UKG-A nrPDB Length = 419 Score = 152 bits (384), Expect = 8e-38, Method: Composition-based stats. Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 33/181 (18%) Query: 13 DGDSIRRET--------GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG 63 +G ++++T ++ + F D++ G ++ +L + +L NP Sbjct: 257 NGPVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE 316 Query: 64 ---DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAF 120 +I DG DFP F+ ++A ++ AF Sbjct: 317 AELQDMINEVDADGDGTFDFPEFLTMMARKMSYRVT----------------EEEIREAF 360 Query: 121 QLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 +++D D +G I E+ V+ + G ++T+E+ D ++ AD DGDG V++ EF + Sbjct: 361 RVFDKDGNGYIGAAELRHVMTDL-GEKLTDEE----VDEMIRVADIDGDGQVNYEEFVQM 415 Query: 181 L 181 + Sbjct: 416 M 416 Score = 80.9 bits (198), Expect = 3e-16, Method: Composition-based stats. Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Query: 92 PVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEE 151 PV + T + + + + AF L+D D DG I+ E+ V+R + G TE Sbjct: 259 PVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEA 317 Query: 152 QLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 +L++ + E D DGDG F EF + + KMS R+ Sbjct: 318 ELQD----MINEVDADGDGTFDFPEFLTMMAR-----KMSYRV 351 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 28/64 (43%), Gaps = 4/64 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGA-LAVNPLG---DRIIESFFPDGSQRVDFPGFV 84 + FR D++ GY+ +L+ + L D +I DG +V++ FV Sbjct: 354 EEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFV 413 Query: 85 RVLA 88 +++ Sbjct: 414 QMMT 417 >4ORC-B nrPDB Length = 170 Score = 151 bits (380), Expect = 3e-37, Method: Composition-based stats. Identities = 61/178 (34%), Positives = 96/178 (53%), Gaps = 16/178 (8%) Query: 17 IRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQ 76 + + F + RL RF+ LD + G LS + + L NPL R+I+ F DG+ Sbjct: 9 LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNG 68 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 VDF F+ ++ F D+ KL +AF++YD+D+DG IS E+ Sbjct: 69 EVDFKEFIEGVSQFSVKGDK----------------EQKLRFAFRIYDMDKDGYISNGEL 112 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 QVL++MVG + + QL+ I D+T+ AD+DGDG +SF EF + +D+ +KM + + Sbjct: 113 FQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 >5B8I-B nrPDB Length = 171 Score = 144 bits (364), Expect = 2e-35, Method: Composition-based stats. Identities = 65/173 (37%), Positives = 94/173 (54%), Gaps = 16/173 (9%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDF 80 + F + RL RF LDR+K G + R + + ++ NPL R+I F DG VDF Sbjct: 13 SNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDF 72 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 FV L+ F ++ KL +AF++YD+DRDG IS E+ VL Sbjct: 73 QEFVSGLSAF----------------SSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVL 116 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIR 193 ++MVG + + QL+ I D+T+ EAD DGDG +SF EFT+ +E DV M++ Sbjct: 117 KMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLD 169 >3WFN-B nrPDB Length = 182 Score = 136 bits (342), Expect = 7e-33, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 11 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 70 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 71 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 114 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 115 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 152 Score = 68.2 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 72 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 73 PEFLTMMARK 82 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 73 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 132 Query: 68 ESFFPDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 133 READIDGDGQVNYEEFVQMMT 153 >2N6A-A nrPDB Length = 173 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 25/162 (15%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRVD 79 ++ + F D++ G ++ +L + +L NP +I DG+ +D Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 66 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 FP F+ ++A D ++ AF+++D D +G IS E+ V Sbjct: 67 FPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRHV 110 Query: 140 LRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 111 MTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 147 Score = 68.2 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 67 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 68 PEFLTMMARK 77 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 68 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 127 Query: 68 ESFFPDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 128 READIDGDGQVNYEEFVQMMT 148 >6O20-F nrPDB Length = 169 Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 25 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 84 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 85 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 128 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 129 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 166 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 86 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 87 PEFLTMMARK 96 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 87 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 146 Query: 68 ESFFPDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 147 READIDGDGQVNYEEFVQMMT 167 >2F2P-A nrPDB Length = 179 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 25/175 (14%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 65 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 108 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIR 193 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + + R Sbjct: 109 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGAAAR 158 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 35/94 (37%), Gaps = 4/94 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 67 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQ 101 DG +V++ FV+++ + Sbjct: 127 READIDGDGQVNYEEFVQMMTAKGGGGGAAARKE 160 >4E53-A nrPDB Length = 185 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 71 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 72 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 115 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 116 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 153 Score = 64.7 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 73 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 74 PEFLTMMARK 83 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 74 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 133 Query: 68 ESFFPDGSQRVDFPGFVRVL 87 DG +V++ FV+++ Sbjct: 134 READIDGDGQVNYEEFVQMM 153 >2JUL-A nrPDB Length = 256 Score = 127 bits (320), Expect = 2e-30, Method: Composition-based stats. Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 34/194 (17%) Query: 6 SHAAVIPDG-DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD 64 S P+G D ++ +T F++ L L+ F+ + G + + I + P GD Sbjct: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYS-QFFPQGD 126 Query: 65 R------IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHY 118 + +F DG+ + F FV L+ + KL + Sbjct: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILL-----------------RGTVHEKLKW 169 Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGA 171 AF LYD+++DG I++ EML +++ + + + E+ +R Q+ D + DG Sbjct: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 Query: 172 VSFVEFTKSLEKMD 185 V+ EF ++ +K + Sbjct: 230 VTIDEFLETCQKDE 243 >5T7C-A nrPDB Length = 193 Score = 127 bits (319), Expect = 3e-30, Method: Composition-based stats. Identities = 43/194 (22%), Positives = 76/194 (39%), Gaps = 33/194 (17%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG 63 + + +R T F+ L + F L G+L+ + ++I A P G Sbjct: 3 KQNSKLRPEVLQDLRENTEFTDHELQEWYKGF--LKDCPTGHLTVDEFKKIYA-NFFPYG 59 Query: 64 D------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLH 117 D + +F +G +DF F+ L+ KL Sbjct: 60 DASKFAEHVFRTFDTNGDGTIDFREFIIALSV-----------------TSRGKLEQKLK 102 Query: 118 YAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT-------EEQLENIADRTVQEADEDGDG 170 +AF +YDLD +G ISR EML++++ + + + E E D+ ++ D + DG Sbjct: 103 WAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDG 162 Query: 171 AVSFVEFTKSLEKM 184 +S EF + + Sbjct: 163 KLSLEEFIRGAKSD 176 >6HCS-A nrPDB Length = 167 Score = 126 bits (316), Expect = 7e-30, Method: Composition-based stats. Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 25/176 (14%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 65 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 108 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 + + G ++T+E+ D ++EAD DGDG V++ EF + + + + Sbjct: 109 FMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAKLEGTGLEVLF 159 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 35/85 (41%), Gaps = 4/85 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRII 67 P+ ++ S + FR D++ GY+S +L+ +G + D +I Sbjct: 67 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMI 126 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRP 92 DG +V++ FV+++ Sbjct: 127 READIDGDGQVNYEEFVQMMTAKLE 151 >5I0I-E nrPDB Length = 145 Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 3 LTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 62 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G IS E+ Sbjct: 63 DFPEFLTMMARKMKDTD----------------SEEEIREAFRVFDKDGNGYISAAELRH 106 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+E+ D ++EAD DGDG V++ EF + + Sbjct: 107 VMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMM 144 Score = 60.1 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 64 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 65 PEFLTMMARK 74 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S + FR D++ GY+S +L+ + L D +I Sbjct: 65 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 124 Query: 68 ESFFPDGSQRVDFPGFVRVLA 88 DG +V++ FV+++ Sbjct: 125 READIDGDGQVNYEEFVQMMT 145 >1S6C-A nrPDB Length = 183 Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats. Identities = 42/188 (22%), Positives = 80/188 (42%), Gaps = 34/188 (18%) Query: 12 PDG-DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----- 65 P+G + + +T F++ L L+ F+ + G ++ +QI A P GD Sbjct: 3 PEGLEQLEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYA-QFFPHGDASTYAH 59 Query: 66 -IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 + +F + V F FV L+ + KL + F LYD Sbjct: 60 YLFNAFDTTQTGSVKFEDFVTALSILL-----------------RGTVHEKLRWTFNLYD 102 Query: 125 LDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +++DG I++ EM+ +++ + + + E+ D Q+ D++ DG V+ EF Sbjct: 103 INKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEF 162 Query: 178 TKSLEKMD 185 +S ++ D Sbjct: 163 LESCQEDD 170 >1BJF-A nrPDB Length = 193 Score = 122 bits (306), Expect = 1e-28, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 78/197 (39%), Gaps = 34/197 (17%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MG ++S + T F++ + + F L G+LS + ++I Sbjct: 1 MGKQNSKL-RPEVMQDLLESTDFTEHEIQEWYKGF--LRDCPSGHLSMEEFKKIYG-NFF 56 Query: 61 PLGD------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN 114 P GD + +F +G +DF F+ L+ Sbjct: 57 PYGDASKFAEHVFRTFDANGDGTIDFREFIIALSV-----------------TSRGKLEQ 99 Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT-------EEQLENIADRTVQEADED 167 KL +AF +YDLD +G IS+ EML++++ + + + E E ++ ++ D + Sbjct: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 168 GDGAVSFVEFTKSLEKM 184 DG +S EF + + Sbjct: 160 RDGKLSLEEFIRGAKSD 176 >1CLM-A nrPDB Length = 148 Score = 122 bits (306), Expect = 1e-28, Method: Composition-based stats. Identities = 38/164 (23%), Positives = 75/164 (45%), Gaps = 25/164 (15%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQR 77 ++ + F D++ G ++ +L + +L NP +I DG+ Sbjct: 3 ELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +DFP F+ ++A +D +L AF+++D D +G IS E+ Sbjct: 63 IDFPEFLSLMARKMKEQD----------------SEEELIEAFKVFDRDGNGLISAAELR 106 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++T+++ D ++EAD DGDG +++ EF + + Sbjct: 107 HVMTNL-GEKLTDDE----VDEMIREADIDGDGHINYEEFVRMM 145 Score = 64.0 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 65 Query: 175 VEFTKSLEKMDVEQ 188 EF + + EQ Sbjct: 66 PEFLSLMARKMKEQ 79 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 4/80 (5%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---I 67 P+ S+ Q S L F+ DR+ G +S +L+ + L D + I Sbjct: 66 PEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMI 125 Query: 68 ESFFPDGSQRVDFPGFVRVL 87 DG +++ FVR++ Sbjct: 126 READIDGDGHINYEEFVRMM 145 >1S1E-A nrPDB Length = 224 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 42/188 (22%), Positives = 80/188 (42%), Gaps = 34/188 (18%) Query: 12 PDG-DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----- 65 P+G + + +T F++ L L+ F+ + G ++ +QI A P GD Sbjct: 36 PEGLEQLEAQTNFTKRELQVLYRGFK--NECPSGVVNEETFKQIYA-QFFPHGDASTYAH 92 Query: 66 -IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 + +F + V F FV L+ + KL + F LYD Sbjct: 93 YLFNAFDTTQTGSVKFEDFVTALSILL-----------------RGTVHEKLRWTFNLYD 135 Query: 125 LDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +++DG I++ EM+ +++ + + + E+ D Q+ D++ DG V+ EF Sbjct: 136 INKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEF 195 Query: 178 TKSLEKMD 185 +S ++ D Sbjct: 196 LESCQEDD 203 >5A2H-A nrPDB Length = 149 Score = 119 bits (299), Expect = 7e-28, Method: Composition-based stats. Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 25/164 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 + + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 5 LTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D +L AF+++D D++G IS E+ Sbjct: 65 DFPEFLNLMARKMKDTD----------------SEEELKEAFRVFDKDQNGFISAAELRH 108 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 V+ + G ++T+E+ D ++EAD DGDG +++ EF K + Sbjct: 109 VMTNL-GEKLTDEE----VDEMIREADVDGDGQINYEEFVKVMM 147 Score = 62.8 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 12 EFKEAFSLFDKDGDGCITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 66 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 67 PEFLNLMARK 76 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRII 67 P+ ++ S L FR D+++ G++S +L+ + L D +I Sbjct: 67 PEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMI 126 Query: 68 ESFFPDGSQRVDFPGFVRVL 87 DG ++++ FV+V+ Sbjct: 127 READVDGDGQINYEEFVKVM 146 >3DD4-A nrPDB Length = 229 Score = 119 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 38/189 (20%), Positives = 82/189 (43%), Gaps = 33/189 (17%) Query: 10 VIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR---- 65 + + ++ F++ L L+ F+ + G ++ ++I + P GD Sbjct: 48 RPEALELLEAQSKFTKKELQILYRGFK--NECPSGVVNEETFKEIYS-QFFPQGDSTTYA 104 Query: 66 --IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 + +F D + V F F++ L+ + + KL++AF LY Sbjct: 105 HFLFNAFDTDHNGAVSFEDFIKGLSILL-----------------RGTVQEKLNWAFNLY 147 Query: 124 DLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGAVSFVE 176 D+++DG I++ EML +++ + + + E+ + Q+ D++ DG V+ E Sbjct: 148 DINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDE 207 Query: 177 FTKSLEKMD 185 F +S +K + Sbjct: 208 FIESCQKDE 216 >5M6C-E nrPDB Length = 193 Score = 118 bits (295), Expect = 2e-27, Method: Composition-based stats. Identities = 45/197 (22%), Positives = 78/197 (39%), Gaps = 34/197 (17%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MG ++S +R T FS+ L + F L G L+ + ++I A Sbjct: 1 MGKQNSKL-RPEMLQDLRENTEFSELELQEWYKGF--LKDCPTGILNVDEFKKIYA-NFF 56 Query: 61 PLGD------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN 114 P GD + +F + +DF F+ L+ Sbjct: 57 PYGDASKFAEHVFRNFDTNSDGTIDFREFIIALSV-----------------TSRGRLEQ 99 Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT-------EEQLENIADRTVQEADED 167 KL +AF +YDLD +G ISR EML++++ + + + E E ++ ++ D + Sbjct: 100 KLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159 Query: 168 GDGAVSFVEFTKSLEKM 184 DG +S EF + + Sbjct: 160 NDGKLSLEEFIRGAKSD 176 >1GGZ-A nrPDB Length = 148 Score = 117 bits (294), Expect = 3e-27, Method: Composition-based stats. Identities = 37/163 (22%), Positives = 73/163 (44%), Gaps = 25/163 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP + + DG+ V Sbjct: 4 LTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTV 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DFP F+ ++A D ++ AF+++D D +G +S E+ Sbjct: 64 DFPEFLGMMARKMKDTDN----------------EEEIREAFRVFDKDGNGFVSAAELRH 107 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 V+ + G ++++E+ D ++ AD DGDG V++ EF + L Sbjct: 108 VMTRL-GEKLSDEE----VDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 64.7 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L + + E D DG+G V F Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSL-GQNPTEAELRD----MMSEIDRDGNGTVDF 65 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 66 PEFLGMMARK 75 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRII 67 P+ + + + FR D++ G++S +L+ ++G + D +I Sbjct: 66 PEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMI 125 Query: 68 ESFFPDGSQRVDFPGFVRVL 87 + DG +V++ FVRVL Sbjct: 126 RAADTDGDGQVNYEEFVRVL 145 >2LAP-A nrPDB Length = 167 Score = 117 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 43/170 (25%), Positives = 74/170 (43%), Gaps = 20/170 (11%) Query: 18 RRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIE---SFFPD 73 R++ + L FR D++K GY++ DL + + P +IE + Sbjct: 14 RKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMN 73 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 VDF FV ++ E D +L AF+ +D + DG+IS Sbjct: 74 LGGHVDFDDFVELMGPKLLAETADMIGV------------KELRDAFREFDTNGDGEIST 121 Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 E+ + +R ++G QV +E I +++ D +GDG V F EF + + + Sbjct: 122 SELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVDFEEFVRMMSR 167 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 42/112 (37%), Gaps = 38/112 (33%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRT------------- 160 +L AF+ +D D+DG I+ ++ +R M G TE +L ++ + Sbjct: 25 EELREAFREFDKDKDGYINCRDLGNCMRTM-GYMPTEMELIELSQQINMNLGGHVDFDDF 83 Query: 161 ------------------------VQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 +E D +GDG +S E +++ K+ Q Sbjct: 84 VELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQ 135 >2L2E-A nrPDB Length = 190 Score = 117 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 46/194 (23%), Positives = 77/194 (39%), Gaps = 33/194 (17%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG 63 +S + R T F + L + + F G+L++ + Q+I P G Sbjct: 3 KSQSKLSQDQLQDLVRSTRFDKKELQQWYKGF--FKDCPSGHLNKSEFQKIYK-QFFPFG 59 Query: 64 D------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLH 117 D + F D + +DF F+ L+ +KL Sbjct: 60 DPSAFAEYVFNVFDADKNGYIDFKEFICALSV-----------------TSRGELNDKLI 102 Query: 118 YAFQLYDLDRDGKISRHEMLQVL---RLMVGVQV----TEEQLENIADRTVQEADEDGDG 170 +AFQLYDLD +G IS EML+++ MVG V E+ E ++ D++ DG Sbjct: 103 WAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDG 162 Query: 171 AVSFVEFTKSLEKM 184 ++ EF + ++ Sbjct: 163 QLTLEEFCEGSKRD 176 >3HZT-A nrPDB Length = 467 Score = 116 bits (290), Expect = 8e-27, Method: Composition-based stats. Identities = 51/174 (29%), Positives = 72/174 (41%), Gaps = 24/174 (13%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL-------QQIGALAVNPLGDRIIESFFPDGSQ 76 + L FR LD N G L R +L Q V+ L IE+ Q Sbjct: 309 TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQ 368 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 VDF R E +E + L R +L AFQ +D D GKI+ E+ Sbjct: 369 SVDFD---------RNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEEL 419 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM-DVEQK 189 RL +V +E + +QE D++ DG V F EF + ++K+ DV+ K Sbjct: 420 G---RLFGVTEVDDETWHQV----LQECDKNNDGEVDFEEFVEMMQKICDVKVK 466 Score = 35.5 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 24/53 (45%) Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 S ++ Q L +G ++T + + ++ D +GDG + E + K+ Sbjct: 291 SSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKL 343 Score = 27.8 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 6/42 (14%), Positives = 16/42 (38%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGA 56 + + R G ++ H + D+N G + + ++ Sbjct: 417 EELGRLFGVTEVDDETWHQVLQECDKNNDGEVDFEEFVEMMQ 458 >2ZFD-A nrPDB Length = 226 Score = 113 bits (283), Expect = 5e-26, Method: Composition-based stats. Identities = 47/193 (24%), Positives = 88/193 (45%), Gaps = 25/193 (12%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQ---IGALAVNPLGDRII 67 D + + R+T FS + + L+ F+ + G +++ + Q + DR+ Sbjct: 32 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 91 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 + F + + F F R L+ F P D +K+H++FQLYDL + Sbjct: 92 DLFDTKHNGILGFEEFARALSVFHPNAPID----------------DKIHFSFQLYDLKQ 135 Query: 128 DGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK-SLEK 183 G I R E+ Q++ + G+ + + +E+I D+T +EAD DG + E+ L Sbjct: 136 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 195 Query: 184 MDVEQKMSIRILK 196 + + M+++ LK Sbjct: 196 PSLLKNMTLQYLK 208 >4JWQ-A nrPDB Length = 199 Score = 113 bits (282), Expect = 6e-26, Method: Composition-based stats. Identities = 34/158 (21%), Positives = 71/158 (44%), Gaps = 21/158 (13%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 L +L F LD + KG +++ L+ + L + D +++ DGS R+D+ F+ Sbjct: 57 LQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 + + + ++ AF+++D+D DG+I+ E+ +L Sbjct: 117 AAALDRK------------------HLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGN 158 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 ++ N + +QE D++ DG + F EF + ++ Sbjct: 159 KKGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMK 196 Score = 27.0 bits (58), Expect = 5.9, Method: Composition-based stats. Identities = 5/41 (12%), Positives = 18/41 (43%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAV 59 ++ +Q + ++ + +D+N G + + ++ L Sbjct: 159 KKGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMKLKY 199 >2L1W-A nrPDB Length = 149 Score = 112 bits (281), Expect = 8e-26, Method: Composition-based stats. Identities = 41/164 (25%), Positives = 78/164 (47%), Gaps = 25/164 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGSQRV 78 S+ ++ F D++ G ++ +L I +L NP + + I DG+ + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 +F F+ ++A D +L AF+++D D++G IS E+ Sbjct: 64 EFDEFLSLMAKKVKDTDA----------------EEELKEAFKVFDKDQNGYISASELRH 107 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 V+ + +G ++T+E++E ++EAD DGDG V++ EF K + Sbjct: 108 VM-INLGEKLTDEEVEQ----MIKEADLDGDGQVNYEEFVKMMM 146 Score = 59.4 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 5/69 (7%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 AF L+D D DG I+ E+ V+R + TEE+L++ + E D DG+G + F Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRSL-DQNPTEEELQD----MISEVDADGNGTIEFD 66 Query: 176 EFTKSLEKM 184 EF + K Sbjct: 67 EFLSLMAKK 75 >3O4Y-A nrPDB Length = 196 Score = 112 bits (280), Expect = 9e-26, Method: Composition-based stats. Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 21/158 (13%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 + +L F LD KG ++++ L+ + L + P D +++ DGS +D+ F+ Sbjct: 54 VQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFL 113 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 R + + ++ AF+++D+D DG+I+ E+ VL Sbjct: 114 AAAIDRRQL------------------SKKLIYCAFRVFDVDNDGEITTAELAHVLFNGN 155 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 E+ N + ++E D++GDG + F EF++ ++ Sbjct: 156 KRGNITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMK 193 Score = 30.1 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 5/40 (12%), Positives = 17/40 (42%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALA 58 + ++ + ++ R +D+N G + + ++ L Sbjct: 156 KRGNITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMKLT 195 >3K21-A nrPDB Length = 191 Score = 110 bits (276), Expect = 3e-25, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 73/158 (46%), Gaps = 21/158 (13%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 + +L F LD + KGY+++ L+ + L + D +++ DGS ++D+ F+ Sbjct: 51 VEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFI 110 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 + + + ++ AF+++D+D DG+I+ E+ +L Sbjct: 111 AAALDRKQL------------------SKKLIYCAFRVFDVDNDGEITTAELAHILYNGN 152 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 ++ N R +++ D++ DG + F EF++ ++ Sbjct: 153 KKGNITQRDVNRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 18/39 (46%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL 57 ++ +Q + R+ R +D+N G + + ++ L Sbjct: 153 KKGNITQRDVNRVKRMIRDVDKNNDGKIDFHEFSEMMKL 191 Score = 26.2 bits (56), Expect = 8.6, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 35/109 (32%), Gaps = 29/109 (26%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVL----------------------------RLMVG 145 KL F + D D G I++ ++ + L + Sbjct: 52 EKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFIA 111 Query: 146 VQVTEEQL-ENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIR 193 + +QL + + + D D DG ++ E L + + ++ R Sbjct: 112 AALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQR 160 >2LCP-A nrPDB Length = 190 Score = 110 bits (275), Expect = 4e-25, Method: Composition-based stats. Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 33/194 (17%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG 63 +S+ + + R+T F++ + + + F + G L Q+I P G Sbjct: 3 KSNSKLKPEVVEELTRKTYFTEKEVQQWYKGF--IKDCPSGQLDAAGFQKIYK-QFFPFG 59 Query: 64 DR------IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLH 117 D + F + R++F F++ L+ + KL Sbjct: 60 DPTKFATFVFNVFDENKDGRIEFSEFIQALSV-----------------TSRGTLDEKLR 102 Query: 118 YAFQLYDLDRDGKISRHEMLQVL---RLMVGVQV----TEEQLENIADRTVQEADEDGDG 170 +AF+LYDLD DG I+R+EML ++ MVG V E E DR D++ DG Sbjct: 103 WAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADG 162 Query: 171 AVSFVEFTKSLEKM 184 ++ EF + + Sbjct: 163 KLTLQEFQEGSKAD 176 >1UHN-A nrPDB Length = 189 Score = 109 bits (272), Expect = 7e-25, Method: Composition-based stats. Identities = 47/193 (24%), Positives = 88/193 (45%), Gaps = 25/193 (12%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQ---IGALAVNPLGDRII 67 D + + R+T FS + + L+ F+ + G +++ + Q + DR+ Sbjct: 1 DPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVF 60 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 + F + + F F R L+ F P D +K+H++FQLYDL + Sbjct: 61 DLFDTKHNGILGFEEFARALSVFHPNAPID----------------DKIHFSFQLYDLKQ 104 Query: 128 DGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK-SLEK 183 G I R E+ Q++ + G+ + + +E+I D+T +EAD DG + E+ L Sbjct: 105 QGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLRH 164 Query: 184 MDVEQKMSIRILK 196 + + M+++ LK Sbjct: 165 PSLLKNMTLQYLK 177 >2JU0-A nrPDB Length = 190 Score = 107 bits (268), Expect = 2e-24, Method: Composition-based stats. Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 34/192 (17%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MG+++S + D +++ T F + + + H F L G L+R D +I Sbjct: 1 MGAKTSKLSKD-DLTCLKQSTYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYK-QFF 56 Query: 61 PLGD------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN 114 P G + F D + + F F+ VL+ + Sbjct: 57 PFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLS-----------------TTSRGTLEE 99 Query: 115 KLHYAFQLYDLDRDGKISRHEMLQV---LRLMVGVQVT----EEQLENIADRTVQEADED 167 KL +AF+LYDL+ DG I+ EML + + M+G VT E E + + D++ Sbjct: 100 KLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKN 159 Query: 168 GDGAVSFVEFTK 179 DG ++ EF + Sbjct: 160 EDGYITLDEFRE 171 Score = 27.0 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 14/32 (43%) Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 E+ A+ D+D +G + F EF L Sbjct: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTT 92 >1V1G-A nrPDB Length = 222 Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats. Identities = 42/194 (21%), Positives = 80/194 (41%), Gaps = 25/194 (12%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRN--KKGYLSRMDLQQIGAL---AVNPLGDRI 66 D + + T F+ + L+ F+ L + G + + + Q N DRI Sbjct: 20 EDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNLFADRI 79 Query: 67 IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLD 126 + F + ++F FVR L F P K+ +AF+LYDL Sbjct: 80 FDVFDVKRNGVIEFGEFVRSLGVFHPSA----------------PVHEKVKFAFKLYDLR 123 Query: 127 RDGKISRHEMLQVLRLMVGVQ---VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE- 182 + G I R E+ +++ ++ ++E+ +E + D+ +AD DG + E+ + Sbjct: 124 QTGFIEREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSL 183 Query: 183 KMDVEQKMSIRILK 196 + + M++ LK Sbjct: 184 NPSLIKNMTLPYLK 197 >2R2I-A nrPDB Length = 198 Score = 106 bits (265), Expect = 5e-24, Method: Composition-based stats. Identities = 38/181 (20%), Positives = 73/181 (40%), Gaps = 26/181 (14%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALA-----VNPLGDRIIESFFPDGSQ 76 S + + +F + G L+ + +Q L N +++ E+F + Sbjct: 10 ELSATECHQWYKKF--MTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDG 67 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 +DF +V L+ KL + F+LYD+D +G I R E+ Sbjct: 68 YIDFMEYVAALSLVLK-----------------GKVDQKLRWYFKLYDVDGNGCIDRGEL 110 Query: 137 LQVLRLMVGVQVTEEQL--ENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 L +++ + + E + E + + D +GDG +S EF + ++K +V + R Sbjct: 111 LNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILTRS 170 Query: 195 L 195 L Sbjct: 171 L 171 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 28/85 (32%), Gaps = 11/85 (12%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI-----------GALAVNPLGDRIIESFFPDGSQR 77 +L F+ D + G + R +L I A+ + + + +G Sbjct: 88 QKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGE 147 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQD 102 + F+ + + D T + D Sbjct: 148 LSLEEFMEGVQKDEVLLDILTRSLD 172 >1TOP-A nrPDB Length = 162 Score = 106 bits (265), Expect = 6e-24, Method: Composition-based stats. Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 22/174 (12%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDR---IIESF 70 S+ + F D + G +S +L + L NP + IIE Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEV 65 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 DGS +DF F+ ++ K + +L F+++D + DG Sbjct: 66 DEDGSGTIDFEEFLVMMVR-------------QMKEDAKGKSEEELANCFRIFDKNADGF 112 Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 I E+ ++LR G VTEE +E++ ++++D++ DG + F EF K +E + Sbjct: 113 IDIEELGEILRA-TGEHVTEEDIEDL----MKDSDKNNDGRIDFDEFLKMMEGV 161 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 36/110 (32%), Gaps = 37/110 (33%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRT-------------- 160 + AF ++D D G IS E+ V+R M+G T+E+L+ I + Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEELDAIIEEVDEDGSGTIDFEEFL 79 Query: 161 ----------------------VQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 + D++ DG + E + L Sbjct: 80 VMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHV 129 >2TN4-A nrPDB Length = 159 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 22/174 (12%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDR---IIESF 70 + S+ + F D + G +S +L + L P + IIE Sbjct: 3 QQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEV 62 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 DGS +DF F+ ++ K + +L F+++D + DG Sbjct: 63 DEDGSGTIDFEEFLVMMVR-------------QMKEDAKGKSEEELAELFRIFDRNADGY 109 Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 I E+ ++ R G VT+E++E++ +++ D++ DG + F EF K +E + Sbjct: 110 IDAEELAEIFRA-SGEHVTDEEIESL----MKDGDKNNDGRIDFDEFLKMMEGV 158 >2LHI-A nrPDB Length = 176 Score = 103 bits (256), Expect = 6e-23, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 71/168 (42%), Gaps = 26/168 (15%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGS 75 + ++ + F D++ G +S +L + +L ++P + + DG+ Sbjct: 2 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 61 Query: 76 QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 +++F F+ +++ D +L AF+++D + DG IS E Sbjct: 62 HQIEFSEFLALMSRQLKSND----------------SEQELLEAFKVFDKNGDGLISAAE 105 Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 + VL + G ++T+ + D ++E DG G ++ +F L K Sbjct: 106 LKHVLTSI-GEKLTDAE----VDDMLREV-SDGSGEINIQQFAALLSK 147 >3KHE-A nrPDB Length = 191 Score = 102 bits (255), Expect = 7e-23, Method: Composition-based stats. Identities = 48/168 (28%), Positives = 68/168 (40%), Gaps = 23/168 (13%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL-------QQIGALAVNPLGDRIIESFFPDGSQ 76 + L FR LD N G L R +L Q V+ L IE+ Q Sbjct: 35 TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQ 94 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 VDF R E +E + L R +L AFQ +D D GKI+ E+ Sbjct: 95 SVDFD---------RNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEEL 145 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 RL +V +E + +QE D++ DG V F EF + ++K+ Sbjct: 146 G---RLFGVTEVDDETWHQV----LQECDKNNDGEVDFEEFVEMMQKI 186 Score = 32.8 bits (73), Expect = 0.092, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 24/53 (45%) Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 S ++ Q L +G ++T + + ++ D +GDG + E + K+ Sbjct: 17 SSQKLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKL 69 >6EPA-A nrPDB Length = 187 Score = 101 bits (252), Expect = 2e-22, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 74/195 (37%), Gaps = 31/195 (15%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MG ++S D + +T F++ + + H F L G L+ +I Sbjct: 1 MGKKNSKLKQD-TIDRLTTDTYFTEKEIRQWHKGF--LKDCPNGLLTEQGFIKIYKQFFP 57 Query: 61 P-----LGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNK 115 + F + ++F F+R L+ + K Sbjct: 58 DGDPSKFASLVFRVFDENNDGAIEFEEFIRALSI-----------------TSRGNLDEK 100 Query: 116 LHYAFQLYDLDRDGKISRHEMLQVL---RLMVGVQV---TEEQLENIADRTVQEADEDGD 169 LH+AF+LYD+D DG I+R EM ++ MVG Q E + D+ + D++ D Sbjct: 101 LHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHD 160 Query: 170 GAVSFVEFTKSLEKM 184 ++ EF + + Sbjct: 161 DRLTLEEFREGSKAD 175 >2LMV-A nrPDB Length = 148 Score = 101 bits (252), Expect = 2e-22, Method: Composition-based stats. Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 25/168 (14%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRIIESFFPDGSQ 76 + ++ + F D+ G ++ +L + L NP +I + + Sbjct: 2 SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNG 61 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 +++F F ++A D ++ AF+++D D DG IS E+ Sbjct: 62 QLNFTEFCGIMAKQMRETDT----------------EEEMREAFKIFDRDGDGFISPAEL 105 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 V+ + +G +VT+E++ D ++EAD DGDG +++ EF + + Sbjct: 106 RFVM-INLGEKVTDEEI----DEMIREADFDGDGMINYEEFVWMISQK 148 >3QRX-A nrPDB Length = 169 Score = 100 bits (248), Expect = 5e-22, Method: Composition-based stats. Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 25/176 (14%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESF 70 D + G ++ + F D + G + +L+ + AL P + I I Sbjct: 14 DQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEI 73 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 DGS +DF F+ ++ D R ++ AF+L+D D G Sbjct: 74 DKDGSGTIDFEEFLTMMTAKMGERD----------------SREEILKAFRLFDDDNSGT 117 Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 I+ ++ +V + + G +TEE+L+ + EAD + D + EF + ++K + Sbjct: 118 ITIKDLRRVAKEL-GENLTEEELQE----MIAEADRNDDNEIDEDEFIRIMKKTSL 168 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 5/86 (5%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ ++ AF L+D D G I E+ +R + EE + + E D+DG G Sbjct: 25 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEE-----IKKMISEIDKDGSG 79 Query: 171 AVSFVEFTKSLEKMDVEQKMSIRILK 196 + F EF + E+ ILK Sbjct: 80 TIDFEEFLTMMTAKMGERDSREEILK 105 >2GGM-A nrPDB Length = 172 Score = 100 bits (248), Expect = 5e-22, Method: Composition-based stats. Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 25/187 (13%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPL 62 + ++ A + + ++ + F D + G + +L+ + AL P Sbjct: 6 KKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPK 65 Query: 63 GDRI---IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 + I I +G+ +++F F+ V+ +D + ++ A Sbjct: 66 KEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDT----------------KEEILKA 109 Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+L+D D GKIS + +V + + G +T+E+L+ + D EAD DGDG VS EF + Sbjct: 110 FKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMID----EADRDGDGEVSEQEFLR 164 Query: 180 SLEKMDV 186 ++K + Sbjct: 165 IMKKTSL 171 Score = 50.5 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 KPE ++ ++ AF L+D D G I E+ +R + EE + + E Sbjct: 22 KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEE-----IKKMISEI 76 Query: 165 DEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 D++G G ++F +F + + E+ ILK Sbjct: 77 DKEGTGKMNFGDFLTVMTQKMSEKDTKEEILK 108 >2NA0-A nrPDB Length = 205 Score = 99.8 bits (247), Expect = 6e-22, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 73/191 (38%), Gaps = 30/191 (15%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALA-----VNPLGDRII 67 DG S+ S + + +F + G L+ + +Q L + +++ Sbjct: 6 DGKSVEE---LSSTECHQWYKKF--MTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMF 60 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 E+F + +DF + L+ KL + F+LYD+D Sbjct: 61 ETFDFNKDGYIDFMEYEAALSLVLK-----------------GKVEQKLRWYFKLYDVDG 103 Query: 128 DGKISRHEMLQVLRLMVGVQVTEE---QLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +G I R E+L ++R + + + E D + D +GDG +S EF + ++K Sbjct: 104 NGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKD 163 Query: 185 DVEQKMSIRIL 195 + R L Sbjct: 164 QMLLDTLTRSL 174 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 13/99 (13%), Positives = 29/99 (29%), Gaps = 12/99 (12%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI------------GALAVNPLGDRIIESFFPDGSQ 76 +L F+ D + G + R +L I + D + +G Sbjct: 90 QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDG 149 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNK 115 + F+ + + + D T + D + + Sbjct: 150 ELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQ 188 >5D43-A nrPDB Length = 178 Score = 98.6 bits (244), Expect = 1e-21, Method: Composition-based stats. Identities = 42/187 (22%), Positives = 80/187 (42%), Gaps = 25/187 (13%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPL 62 R S+ A + + ++ + F D + G + +L+ + AL P Sbjct: 6 RKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR 65 Query: 63 GDRI---IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 + + I + + ++ F F+ V+ +D + ++ A Sbjct: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDT----------------KEEILKA 109 Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+L+D D GKIS + +V + G +T+E+L+ + D EAD DGDG V+ EF K Sbjct: 110 FRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMID----EADRDGDGEVNEEEFLK 164 Query: 180 SLEKMDV 186 ++K ++ Sbjct: 165 IMKKTNL 171 Score = 52.0 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 KPE ++ ++ AF L+D D G I E+ +R + EE + + E Sbjct: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE-----MKKMISEV 76 Query: 165 DEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 D++ G +SF +F + + E+ ILK Sbjct: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILK 108 >4DS7-A nrPDB Length = 147 Score = 98.6 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 69/166 (41%), Gaps = 26/166 (15%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGSQR 77 ++ + F D++ G +S +L + +L ++P + + DG+ Sbjct: 4 NLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDGNHA 63 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 ++F F+ +++ D +L AF+++D + DG IS E+ Sbjct: 64 IEFSEFLALMSRQLKCND----------------SEQELLEAFKVFDKNGDGLISAAELK 107 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 VL + G ++T+ + D ++E DG G ++ +F L K Sbjct: 108 HVLTSI-GEKLTDAE----VDEMLREV-SDGSGEINIKQFAALLSK 147 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 5/73 (6%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D G IS E+ V+R + G+ +E ++ ++ + E D DG+ A+ F Sbjct: 12 EFKEAFALFDKDNSGSISASELATVMRSL-GLSPSEAEVADL----MNEIDVDGNHAIEF 66 Query: 175 VEFTKSLEKMDVE 187 EF + + Sbjct: 67 SEFLALMSRQLKC 79 >1JBA-A nrPDB Length = 204 Score = 98.3 bits (243), Expect = 2e-21, Method: Composition-based stats. Identities = 41/183 (22%), Positives = 71/183 (38%), Gaps = 35/183 (19%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN----PLGDRIIESFFPDGSQRVD 79 A L + +F L+ G L + ++ + N + + +F +G +D Sbjct: 20 DAAQLQEWYKKF--LEECPSGTLFMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNTID 77 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F +V L + +KL + F++YD DR+G I R E+L + Sbjct: 78 FLEYVAALNLVL-----------------RGTLEHKLKWTFKIYDKDRNGCIDRQELLDI 120 Query: 140 LRLMVGVQ------VTEEQ------LENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVE 187 + + ++ V EQ E + DR DE+GDG +S EF + + Sbjct: 121 VESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWV 180 Query: 188 QKM 190 KM Sbjct: 181 MKM 183 >1LKJ-A nrPDB Length = 146 Score = 97.5 bits (241), Expect = 4e-21, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 71/168 (42%), Gaps = 26/168 (15%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGS 75 + ++ + F D++ G +S +L + +L ++P + + DG+ Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 76 QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 +++F F+ +++ D +L AF+++D + DG IS E Sbjct: 61 HQIEFSEFLALMSRQLKSND----------------SEQELLEAFKVFDKNGDGLISAAE 104 Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 + VL + G ++T+ + D ++E DG G ++ +F L K Sbjct: 105 LKHVLTSI-GEKLTDAE----VDDMLREV-SDGSGEINIQQFAALLSK 146 >3J04-B nrPDB Length = 143 Score = 96.7 bits (239), Expect = 5e-21, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 67/161 (41%), Gaps = 23/161 (14%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVDFP 81 F Q+ + F +D+N+ G++ + DL + ++ NP D +E + ++F Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPT-DEYLEGMMSEAPGPINFT 59 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 F+ + D + + AF +D + G I + ++L Sbjct: 60 MFLTMFGEKLNGTDP----------------EDVIRNAFACFDEEASGFIHEDHLRELLT 103 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 M G + T+E+ D +EA D G ++VEFT+ L+ Sbjct: 104 TM-GDRFTDEE----VDEMYREAPIDKKGNFNYVEFTRILK 139 >3KF9-A nrPDB Length = 149 Score = 96.7 bits (239), Expect = 6e-21, Method: Composition-based stats. Identities = 44/169 (26%), Positives = 76/169 (44%), Gaps = 25/169 (14%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGSQR 77 G ++ + F D + G + +L+ + AL P + I I DGS Sbjct: 1 GLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGT 60 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +DF F++++ D R ++ AF+L+D D GKIS + Sbjct: 61 IDFEEFLQMMTAKMGERD----------------SREEIMKAFRLFDDDETGKISFKNLK 104 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 +V + + G +T+E+L+ + D EAD DGDG V+ EF + ++K + Sbjct: 105 RVAKEL-GENMTDEELQEMID----EADRDGDGEVNEEEFFRIMKKTSL 148 >3NCG-A nrPDB Length = 486 Score = 95.9 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 40/178 (22%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL-------QQIGALAVNPL----GDRIIESFFP 72 + +L FR LD N G L R +L ++ + N L G I + Sbjct: 326 TLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDS 385 Query: 73 -------DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDL 125 DGS +++ F+ + R ++ AF+++D Sbjct: 386 LMPLLDMDGSGSIEYSEFIA-----------------SAIDRTILLSRERMERAFKMFDK 428 Query: 126 DRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 D GKIS E+ ++ + E+LE+I +++ D + DG V F EF + L+ Sbjct: 429 DGSGKISTKELFKLFSQ-ADSSIQMEELESI----IEQVDNNKDGEVDFNEFVEMLQN 481 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----IIESFFPDGSQRVDFPGFV 84 R+ F+ D++ G +S +L ++ + A + + IIE + VDF FV Sbjct: 417 ERMERAFKMFDKDGSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFV 476 Query: 85 RVLAHFRPVE 94 +L +F E Sbjct: 477 EMLQNFVRNE 486 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 46/138 (33%), Gaps = 8/138 (5%) Query: 53 QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSR 112 ++ L I + +D VR F ++ D+ + + + + Sbjct: 323 KLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQ 382 Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 + L L D+D G I E + + T +R + D+DG G + Sbjct: 383 IDSLM---PLLDMDGSGSIEYSEF-----IASAIDRTILLSRERMERAFKMFDKDGSGKI 434 Query: 173 SFVEFTKSLEKMDVEQKM 190 S E K + D +M Sbjct: 435 STKELFKLFSQADSSIQM 452 Score = 29.3 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 17/46 (36%) Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 ++ Q L + ++T ++ D + DG + E + Sbjct: 310 KKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVR 355 >5JN2-A nrPDB Length = 525 Score = 91.7 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 38/176 (21%), Positives = 67/176 (38%), Gaps = 39/176 (22%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSR-------MDLQQIGALAVNPLG--------DRIIE 68 SQ L F +D+N G L R +L ++ + L D++++ Sbjct: 371 SQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLD 430 Query: 69 SFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRD 128 + D + +++ FV R +L AF+++D D Sbjct: 431 AVDFDKNGYIEYSEFVT-----------------VAMDRKTLLSRERLERAFRMFDSDNS 473 Query: 129 GKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 GKIS E+ + V E +++ + E D++ DG V F EF + L K+ Sbjct: 474 GKISSTELATI---FGVSDVDSETWKSV----LSEVDKNNDGEVDFDEFQQMLLKL 522 Score = 34.3 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 9/52 (17%), Positives = 23/52 (44%) Query: 133 RHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 ++ Q L +G ++T + + D++GDG + E + +++ Sbjct: 354 TQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKEL 405 >2OBH-A nrPDB Length = 143 Score = 91.3 bits (225), Expect = 2e-19, Method: Composition-based stats. Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 25/164 (15%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGSQRVD 79 ++ + F D + G + +L+ + AL P + I I +G+ +++ Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 60 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F F+ V+ +D + ++ AF+L+D D GKIS + +V Sbjct: 61 FGDFLTVMTQKMSEKDT----------------KEEILKAFKLFDDDETGKISFKNLKRV 104 Query: 140 LRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 + + G +T+E+L+ + D EAD DGDG VS EF + ++K Sbjct: 105 AKEL-GENLTDEELQEMID----EADRDGDGEVSEQEFLRIMKK 143 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 5/86 (5%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ ++ AF L+D D G I E+ +R + EE + + E D++G G Sbjct: 3 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEE-----IKKMISEIDKEGTG 57 Query: 171 AVSFVEFTKSLEKMDVEQKMSIRILK 196 ++F +F + + E+ ILK Sbjct: 58 KMNFGDFLTVMTQKMSEKDTKEEILK 83 >3Q5I-A nrPDB Length = 504 Score = 89.4 bits (220), Expect = 8e-19, Method: Composition-based stats. Identities = 33/173 (19%), Positives = 63/173 (36%), Gaps = 36/173 (20%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN------------PLGDRIIESFF 71 + L F+ LD+N G L + +L + + N D I++ Sbjct: 350 TLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVD 409 Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 D + +++ F+ + + +L AF L+D D+ GKI Sbjct: 410 FDKNGYIEYSEFIS-----------------VCMDKQILFSEERLRRAFNLFDTDKSGKI 452 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 ++ E+ + L E + + EAD++ D + F EF + K+ Sbjct: 453 TKEELANLFGL-------TSISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKI 498 Score = 51.3 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 3/85 (3%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ---VLRLMVGVQVTEEQLENIADRTV 161 R +L F+ D + DG++ + E+++ VLR + +E D + Sbjct: 346 SKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNIL 405 Query: 162 QEADEDGDGAVSFVEFTKSLEKMDV 186 +E D D +G + + EF + Sbjct: 406 KEVDFDKNGYIEYSEFISVCMDKQI 430 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 46/143 (32%), Gaps = 14/143 (9%) Query: 53 QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSR 112 ++ L I + +G ++D + R ++E E L + Sbjct: 347 KLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGE---------LKNV 397 Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 ++ + D D++G I E + V M + E+ R D D G + Sbjct: 398 EEEVDNILKEVDFDKNGYIEYSEFISV--CMDKQILFSEE---RLRRAFNLFDTDKSGKI 452 Query: 173 SFVEFTKSLEKMDVEQKMSIRIL 195 + E + +K +L Sbjct: 453 TKEELANLFGLTSISEKTWNDVL 475 >4MVF-A nrPDB Length = 506 Score = 89.0 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 24/163 (14%) Query: 27 SLLRLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 + L + F ALD + G LS + L++IG + P +++ + S ++ + Sbjct: 358 EINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTD 417 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ + ++ F+ +D+D +GKIS E+ ++ Sbjct: 418 FLAA-----------------TIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRI--- 457 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 + ++ D +QE D +GDG + F EF + K++ Sbjct: 458 FGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 37/95 (38%), Gaps = 5/95 (5%) Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 ++ L +F+ + + N L F D+D G +S E+L L+ + Sbjct: 330 LKNLKNFKKENELKKIALTIIAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKI 389 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 ++ + + +++ D + G + + +F Sbjct: 390 GYQKIPPD-----IHQVLRDIDSNASGQIHYTDFL 419 >2JNF-A nrPDB Length = 158 Score = 89.0 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 22/171 (12%) Query: 21 TGFSQASLLRLHHRFRALDR-NKKGYLSRMDLQQIGAL----AVNPLGDRIIESFFPDGS 75 + S + L FR + G +S + I + ++I+ F P G+ Sbjct: 5 SKLSSNQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPFGN 64 Query: 76 QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 +DF F + A F E + + +L AF+LYD + +G IS Sbjct: 65 GDIDFDSFKIIGARFLGEEVNPEQ------------MQQELREAFRLYDKEGNGYISTDV 112 Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 M ++L ++ E D + E D DG G V F EF + D Sbjct: 113 MREIL-----AELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMTGGDE 158 >2I94-A nrPDB Length = 202 Score = 89.0 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 40/194 (20%), Positives = 72/194 (37%), Gaps = 35/194 (18%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN 60 MG+ S A + ++ T F++ L + F L G ++R + Q I + Sbjct: 1 MGNSKSGALSKEILEELQLNTKFTEEELSSWYQSF--LKECPSGRITRQEFQTIYS-KFF 57 Query: 61 PLGD------RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN 114 P D + SF + +DF +V L Sbjct: 58 PEADPKAYAQHVFRSFDANSDGTLDFKEYVIAL-----------------HMTSAGKTNQ 100 Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV---------TEEQLENIADRTVQEAD 165 KL +AF LYD+D +G IS++E+L+++ + + E E A++ Sbjct: 101 KLEWAFSLYDVDGNGTISKNEVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFG 160 Query: 166 EDGDGAVSFVEFTK 179 + D ++ EF + Sbjct: 161 KKDDDKLTEKEFIE 174 >1DGU-A nrPDB Length = 183 Score = 88.6 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 79/176 (44%), Gaps = 29/176 (16%) Query: 21 TGFSQASLLRLHHRF--------RALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP 72 T ++ +L H RF R+++ + + + + + L NP +RI F Sbjct: 12 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 71 Query: 73 DGSQ-RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 ++ + F F+ +L+ F D K HYAF+++D D DG + Sbjct: 72 SPAKDSLSFEDFLDLLSVFSDTATPDI----------------KSHYAFRIFDFDDDGTL 115 Query: 132 SRHEMLQVLRLMVGV----QVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 +R ++ +++ + G +++ +++ + D ++E+D D DG ++ EF + + Sbjct: 116 NREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 171 >2AAO-A nrPDB Length = 166 Score = 88.6 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 64/165 (38%), Gaps = 28/165 (16%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESF---FPDGSQRV 78 S+ + L F +D +K G ++ +L+ + + N I++ D S + Sbjct: 21 LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTI 80 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 D+ F+ H +E R + L AF +D D G I+ E+ Q Sbjct: 81 DYKEFIAATLHLNKIE-----------------REDHLFAAFTYFDKDGSGYITPDELQQ 123 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 V E+L +++ D+D DG + + EF ++K Sbjct: 124 ACEEFGVEDVRIEEL-------MRDVDQDNDGRIDYNEFVAMMQK 161 Score = 30.5 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 40/123 (32%), Gaps = 22/123 (17%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 + D S ++ F L K N + +++ Q D Sbjct: 31 EMFNMIDADKSGQITFEELKAGL-----------------KRVGANLKESEILDLMQAAD 73 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +D G I E + + + + E+ D+DG G ++ E ++ E+ Sbjct: 74 VDNSGTIDYKEFIAATLHLNKI-----EREDHLFAAFTYFDKDGSGYITPDELQQACEEF 128 Query: 185 DVE 187 VE Sbjct: 129 GVE 131 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQK 189 ++ ++ ++EE++ + D D G ++F E L+++ K Sbjct: 10 KKMALRVIAESLSEEEIAGL-KEMFNMIDADKSGQITFEELKAGLKRVGANLK 61 >3LIJ-A nrPDB Length = 494 Score = 88.2 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 61/173 (35%), Gaps = 36/173 (20%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL------------AVNPLGDRIIESFF 71 SQ L FR +D+N G L R +L + + D I+ + Sbjct: 341 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 400 Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 D + +D+ FV ++KL AFQ +D D +GKI Sbjct: 401 FDRNGYIDYSEFVT-----------------VAMDRKSLLSKDKLESAFQKFDQDGNGKI 443 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 S E+ V L + + D + DG V F EF K ++K+ Sbjct: 444 SVDELASVFGL-------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKL 489 Score = 49.0 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 32/81 (39%), Gaps = 5/81 (6%) Query: 17 IRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALA--VNPLGDRIIESFFPDG 74 + R++ S+ +L F+ D++ G +S +L + L + +I + Sbjct: 417 MDRKSLLSKD---KLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNN 473 Query: 75 SQRVDFPGFVRVLAHFRPVED 95 VDF F +++ + Sbjct: 474 DGDVDFEEFCKMIQKLCSNNE 494 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 38/125 (30%), Gaps = 14/125 (11%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 I +G ++D + + E + + D Sbjct: 350 DIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAA---------D 400 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 DR+G I E + V + ++ + Q+ D+DG+G +S E Sbjct: 401 FDRNGYIDYSEFVTVAMDRKSLLSKDK-----LESAFQKFDQDGNGKISVDELASVFGLD 455 Query: 185 DVEQK 189 +E K Sbjct: 456 HLESK 460 Score = 31.6 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 25/63 (39%) Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMS 191 + ++ Q L + ++T ++ + D++GDG + E K+ E+ Sbjct: 323 NSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAV 382 Query: 192 IRI 194 + Sbjct: 383 FDL 385 Score = 27.0 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 5/40 (12%), Positives = 11/40 (27%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQI 54 D + G +D N G + + ++ Sbjct: 446 DELASVFGLDHLESKTWKEMISGIDSNNDGDVDFEEFCKM 485 >4YZB-A nrPDB Length = 491 Score = 87.9 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 23/168 (13%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQ-------IGALAVNPLGDRIIESFFPDGSQ 76 + + L+ F+ +D+N G L + +L + + V+ L IE Sbjct: 334 TNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLD 393 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 VDF + E +E R +L AF ++D D GKIS E+ Sbjct: 394 AVDFD---------KNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSEL 444 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + +V E R + E D + DG V F EF + L K+ Sbjct: 445 ATI---FGVSEVDSETWR----RVLAEVDRNNDGEVDFEEFRQMLLKL 485 Score = 43.6 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 11/131 (8%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 +I + +G ++D + ++ ED D E ++ D Sbjct: 343 KIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEF------EVEQVLDAVD 396 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 D++G I E + V + +R D DG G +S E Sbjct: 397 FDKNGFIEYSEFVTV-----AMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFGVS 451 Query: 185 DVEQKMSIRIL 195 +V+ + R+L Sbjct: 452 EVDSETWRRVL 462 Score = 35.1 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 21/47 (44%) Query: 133 RHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 ++ L +G ++T + ++ Q D++GDG + E + Sbjct: 317 TQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELME 363 >2M29-A nrPDB Length = 171 Score = 87.9 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 37/154 (24%), Positives = 61/154 (39%), Gaps = 20/154 (12%) Query: 33 HRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIES---FFPDGSQRVDFPGFVRVLA 88 F D ++ GY+ +L + L P ++E VDF FV +++ Sbjct: 32 AAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELIS 91 Query: 89 HFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV 148 E +L AF+ +D DRDG+I+ E+ Q ++G + Sbjct: 92 PKLREETAHMLGV------------RELRIAFREFDKDRDGRITVAELRQAAPALLGEPL 139 Query: 149 TEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 +L D ++E D +GDG + F EF L Sbjct: 140 EGTEL----DEMLREMDLNGDGTIDFDEFVMMLS 169 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLG----DRIIESFFPDGSQRVDFPG 82 + L FR D+++ G ++ +L+Q AL PL D ++ +G +DF Sbjct: 104 VRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDE 163 Query: 83 FVRVLA 88 FV +L+ Sbjct: 164 FVMMLS 169 >2LM5-A nrPDB Length = 214 Score = 87.5 bits (215), Expect = 3e-18, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 79/176 (44%), Gaps = 29/176 (16%) Query: 21 TGFSQASLLRLHHRF--------RALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP 72 T ++ +L H RF R+++ + + + + + L NP +RI F Sbjct: 43 TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFST 102 Query: 73 DGSQ-RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 ++ + F F+ +L+ F D K HYAF+++D D DG + Sbjct: 103 SPAKDSLSFEDFLDLLSVFSDTATPDI----------------KSHYAFRIFDFDDDGTL 146 Query: 132 SRHEMLQVLRLMVGV----QVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 +R ++ +++ + G +++ +++ + D ++E+D D DG ++ EF + + Sbjct: 147 NREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 202 >4RGJ-A nrPDB Length = 520 Score = 87.1 bits (214), Expect = 4e-18, Method: Composition-based stats. Identities = 37/176 (21%), Positives = 65/176 (36%), Gaps = 39/176 (22%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSR-------MDLQQIGALAVNPLG--------DRIIE 68 + L F+ +D+N G L R +L ++ + L D+I+ Sbjct: 366 TIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILN 425 Query: 69 SFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRD 128 S D + +++ F+ L +L AF+L+D D Sbjct: 426 SIDLDQNGYIEYSEFLT-----------------VSIDRKLLLSTERLEKAFKLFDKDGS 468 Query: 129 GKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 GKIS +E+ Q+ L + ++E D++ DG + F EF L K+ Sbjct: 469 GKISANELAQLFGL-------SDVSSECWKTVLKEVDQNNDGEIDFKEFRDMLVKL 517 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 11/132 (8%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 +I + +G ++D + ++ EDT D + ++ D Sbjct: 375 KIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNA------AIEYEVDQILNSID 428 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 LD++G I E L V + + ++ E+LE + + D+DG G +S E + Sbjct: 429 LDQNGYIEYSEFLTV-SIDRKLLLSTERLE----KAFKLFDKDGSGKISANELAQLFGLS 483 Query: 185 DVEQKMSIRILK 196 DV + +LK Sbjct: 484 DVSSECWKTVLK 495 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 21/45 (46%) Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVE 176 S ++ Q L +G ++T + ++ D++GDG + E Sbjct: 348 STQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNE 392 >2LHH-A nrPDB Length = 128 Score = 86.7 bits (213), Expect = 5e-18, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 60/139 (43%), Gaps = 21/139 (15%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGS 75 + ++ + F D++ G +S +L + +L ++P + + DG+ Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 76 QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 +++F F+ +++ D +L AF+++D + DG IS E Sbjct: 61 HQIEFSEFLALMSRQLKSND----------------SEQELLEAFKVFDKNGDGLISAAE 104 Query: 136 MLQVLRLMVGVQVTEEQLE 154 + VL + G ++T+ +LE Sbjct: 105 LKHVLTSI-GEKLTDAELE 122 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D +G IS E+ V+R + G+ +E ++ ++ + E D DG+ + F Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSL-GLSPSEAEVNDL----MNEIDVDGNHQIEF 65 Query: 175 VEFTKSLEK 183 EF + + Sbjct: 66 SEFLALMSR 74 >2GGZ-A nrPDB Length = 211 Score = 85.9 bits (211), Expect = 9e-18, Method: Composition-based stats. Identities = 28/165 (16%), Positives = 56/165 (33%), Gaps = 25/165 (15%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL-----AVNPLGDRIIESFFPDGSQRVDF 80 + F G + + + + L N D++ +F + VDF Sbjct: 19 QETHVWYRTFMM--EYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDF 76 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 F+ + + KL + F+LYD D +G I ++E+L + Sbjct: 77 LEFIAAVNLIMQEK-----------------MEQKLKWYFKLYDADGNGSIDKNELLDMF 119 Query: 141 RLMVGVQVTEE-QLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + + + E + + D + DG ++ EF + K Sbjct: 120 MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKD 164 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 16/118 (13%), Positives = 39/118 (33%), Gaps = 15/118 (12%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDL----QQIGALAVNPLGDRIIESFFPDGSQR 77 G +Q + + + D NK G++ ++ I + + + DG+ Sbjct: 50 GLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGS 109 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 +D + + + S ++ F D++ DG+++ E Sbjct: 110 IDKNELLDMF-----------MAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEE 156 Score = 35.5 bits (80), Expect = 0.016, Method: Composition-based stats. Identities = 8/74 (10%), Positives = 22/74 (29%), Gaps = 10/74 (13%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----------IIESFFPDG 74 + +L F+ D + G + + +L + G + + + Sbjct: 89 EKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINN 148 Query: 75 SQRVDFPGFVRVLA 88 + F+ +A Sbjct: 149 DGELTLEEFINGMA 162 >1DTL-A nrPDB Length = 161 Score = 82.8 bits (203), Expect = 7e-17, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 69/168 (41%), Gaps = 23/168 (13%) Query: 23 FSQASLLRLHHRFRALD-RNKKGYLSRMDLQQ-IGALAVNPL---GDRIIESFFPDGSQR 77 ++ F + G +S +L + + L NP +I+ DGS Sbjct: 12 LTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 71 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 VDF F+ ++ K + +L F+++D + DG I E+ Sbjct: 72 VDFDEFLVMMVR-------------SMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELK 118 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 ++ G +TE+ +E + +++ D++ DG + + EF + ++ ++ Sbjct: 119 -IMLQATGETITEDDIEEL----MKDGDKNNDGRIDYDEFLEFMKGVE 161 >5YPX-A nrPDB Length = 223 Score = 82.8 bits (203), Expect = 8e-17, Method: Composition-based stats. Identities = 35/139 (25%), Positives = 60/139 (43%), Gaps = 21/139 (15%) Query: 43 KGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQD 102 L R L Q + + L DR+ +F D + +V L+ F Sbjct: 63 DRNLFRDILHQKFNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFL----------- 111 Query: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQ----LENIAD 158 + K+ Y F ++DL+ DG ISR EM Q+L+ + Q TEE ++++ + Sbjct: 112 ------RGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPTEEDPDEGIKDLVE 165 Query: 159 RTVQEADEDGDGAVSFVEF 177 +++ D D D +S +F Sbjct: 166 IALKKMDHDHDSRLSKKDF 184 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 42/105 (40%), Gaps = 5/105 (4%) Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 + ++ + +D + + + F+ +D D D IS E ++ L + Sbjct: 51 ICYKNLLEGLKMDRNLFRDILHQKFNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVF 110 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 + + E+ + T D +GDG +S E + L+ V+Q Sbjct: 111 LRGTLDEK-----MEYTFTVFDLNGDGYISREEMFQMLKTCLVKQ 150 >4WPX-A nrPDB Length = 177 Score = 82.8 bits (203), Expect = 8e-17, Method: Composition-based stats. Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 7/161 (4%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVDFP 81 S R+ F D NK G LS + + + AL + + + G + ++P Sbjct: 20 LSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWP 79 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 +R + + R ++L AF+L+D+D G I+ ++ +V + Sbjct: 80 HDQECPPVYRQFNLATAQALAGTLIRQRDPR-DELRRAFRLFDVDGKGMITEDDLRKVCQ 138 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 VG + + ++ ++E D +G G V EF + + Sbjct: 139 Q-VGNNIPDADIQA----MIEEFDSNGKGGVDEDEFLRLMM 174 Score = 33.2 bits (74), Expect = 0.068, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 39/119 (32%), Gaps = 44/119 (36%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV------------------------- 144 + ++ ++ AF+L+D ++DG +S E VLR + Sbjct: 22 DEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWPHD 81 Query: 145 -------------------GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 G + + + R + D DG G ++ + K +++ Sbjct: 82 QECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQV 140 >3PM8-A nrPDB Length = 197 Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 65/162 (40%), Gaps = 24/162 (14%) Query: 27 SLLRLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 + L + F ALD + G LS + L++IG + P +++ + S ++ + Sbjct: 55 EINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTD 114 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ + ++ F+ +D+D +GKIS E+ ++ Sbjct: 115 FLAA-----------------TIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRI--- 154 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + ++ D +QE D +GDG + F EF + K Sbjct: 155 FGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKK 196 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 6/63 (9%) Query: 35 FRALDRNKKGYLSRMDLQQIGALAV--NPLGDRIIE----SFFPDGSQRVDFPGFVRVLA 88 F+ D + G +S +L++I NPL D+ I+ +G +DF F+ +++ Sbjct: 135 FKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMS 194 Query: 89 HFR 91 + Sbjct: 195 KKK 197 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 37/95 (38%), Gaps = 5/95 (5%) Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 ++ L +F+ + + N L F D+D G +S E+L L+ + Sbjct: 27 LKNLKNFKKENELKKIALTIIAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKI 86 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 ++ + + +++ D + G + + +F Sbjct: 87 GYQKIPPD-----IHQVLRDIDSNASGQIHYTDFL 116 Score = 28.1 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 135 EMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 E+ ++ ++ + + ++ N+ + + D D G +S E L+K+ Sbjct: 38 ELKKIALTIIAKHLCDVEINNLRNIFIA-LDVDNSGTLSSQEILDGLKKI 86 >1S6I-A nrPDB Length = 188 Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 60/166 (36%), Gaps = 28/166 (16%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFP---DGSQR 77 S+ + L F+ +D + G ++ +L+ + + + I + D S Sbjct: 3 RLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGT 62 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +D+ F+ H +E R L AF +D D G I+ E+ Sbjct: 63 IDYGEFIAATVHLNKLE-----------------REENLVSAFSYFDKDGSGYITLDEIQ 105 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 Q + + D ++E D+D DG + + EF + K Sbjct: 106 QACKDFGLDDI-------HIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 14 GDSIRRETGFSQASLLR-LHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLG-DRIIESF 70 G+ I ++ L F D++ GY++ ++QQ ++ + D +I+ Sbjct: 66 GEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFGLDDIHIDDMIKEI 125 Query: 71 FPDGSQRVDFPGFVRVLAHFRPV 93 D ++D+ F ++ + Sbjct: 126 DQDNDGQIDYGEFAAMMRKRKGN 148 Score = 27.4 bits (59), Expect = 4.3, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 146 VQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +++EE++ + + D D G ++F E L+++ Sbjct: 2 ERLSEEEIGGL-KELFKMIDTDNSGTITFDELKDGLKRV 39 >2D8N-A nrPDB Length = 207 Score = 82.1 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 67/186 (36%), Gaps = 33/186 (17%) Query: 8 AAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG---- 63 A + ++ T FS+ L + F L G +++ Q I A Sbjct: 15 ALSKEILEELQLNTKFSEEELCSWYQSF--LKDCPTGRITQQQFQSIYAKFFPDTDPKAY 72 Query: 64 -DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 + SF + +DF +V L KL +AF L Sbjct: 73 AQHVFRSFDSNLDGTLDFKEYVIAL-----------------HMTTAGKTNQKLEWAFSL 115 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQV---------TEEQLENIADRTVQEADEDGDGAVS 173 YD+D +G IS++E+L+++ + + E E A++ + ++ D ++ Sbjct: 116 YDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLT 175 Query: 174 FVEFTK 179 EF + Sbjct: 176 EKEFIE 181 >2E6W-A nrPDB Length = 100 Score = 82.1 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 46/84 (54%), Gaps = 7/84 (8%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTV 161 + + KL +AF LYD+++DG I++ EML +++ + + + E+ +R Sbjct: 4 MGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFF 63 Query: 162 QEADEDGDGAVSFVEFTKSLEKMD 185 ++ D + DG V+ EF ++ +K + Sbjct: 64 EKMDRNQDGVVTIEEFLEACQKDE 87 Score = 29.7 bits (65), Expect = 0.91, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 24/74 (32%), Gaps = 16/74 (21%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG----------------DRIIESFFP 72 +L F D NK GY+++ ++ I + +G +R E Sbjct: 9 EKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDR 68 Query: 73 DGSQRVDFPGFVRV 86 + V F+ Sbjct: 69 NQDGVVTIEEFLEA 82 >3L19-A nrPDB Length = 214 Score = 81.7 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 61/173 (35%), Gaps = 36/173 (20%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL------------AVNPLGDRIIESFF 71 SQ L FR +D+N G L R +L + + D I+ + Sbjct: 58 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 117 Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 D + +D+ FV ++KL AFQ +D D +GKI Sbjct: 118 FDRNGYIDYSEFVT-----------------VAMDRKSLLSKDKLESAFQKFDQDGNGKI 160 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 S E+ V L + + D + DG V F EF K ++K+ Sbjct: 161 SVDELASVFGL-------DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKL 206 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 32/81 (39%), Gaps = 5/81 (6%) Query: 17 IRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALA--VNPLGDRIIESFFPDG 74 + R++ S+ +L F+ D++ G +S +L + L + +I + Sbjct: 134 MDRKSLLSKD---KLESAFQKFDQDGNGKISVDELASVFGLDHLESKTWKEMISGIDSNN 190 Query: 75 SQRVDFPGFVRVLAHFRPVED 95 VDF F +++ + Sbjct: 191 DGDVDFEEFCKMIQKLCSNNE 211 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 38/125 (30%), Gaps = 14/125 (11%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 I +G ++D + + E + + D Sbjct: 67 DIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAA---------D 117 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 DR+G I E + V + ++ + Q+ D+DG+G +S E Sbjct: 118 FDRNGYIDYSEFVTVAMDRKSLLSKDK-----LESAFQKFDQDGNGKISVDELASVFGLD 172 Query: 185 DVEQK 189 +E K Sbjct: 173 HLESK 177 Score = 29.7 bits (65), Expect = 0.74, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 25/63 (39%) Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMS 191 + ++ Q L + ++T ++ + D++GDG + E K+ E+ Sbjct: 40 NSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAV 99 Query: 192 IRI 194 + Sbjct: 100 FDL 102 >3FWC-A nrPDB Length = 161 Score = 80.9 bits (198), Expect = 3e-16, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 66/166 (39%), Gaps = 25/166 (15%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGS 75 + + ++ F D N G+L +L+ + AL I I+ + +G Sbjct: 14 NSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGR 73 Query: 76 QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 + + F V+ D +++ AFQL+D D GKIS Sbjct: 74 HLMKYDDFYIVMGEKILKRDPL----------------DEIKRAFQLFDDDHTGKISIKN 117 Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + +V + + G +T+E+L ++E D DGDG ++ EF Sbjct: 118 LRRVAKEL-GETLTDEELRA----MIEEFDLDGDGEINENEFIAIC 158 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 33/88 (37%), Gaps = 4/88 (4%) Query: 3 SRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNP 61 S H D + E + L + F+ D + G +S +L+++ L Sbjct: 70 SEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETL 129 Query: 62 LGDRI---IESFFPDGSQRVDFPGFVRV 86 + + IE F DG ++ F+ + Sbjct: 130 TDEELRAMIEEFDLDGDGEINENEFIAI 157 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 44/95 (46%), Gaps = 5/95 (5%) Query: 94 EDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL 153 ++ + P E L ++ +++ AF L+D++ DG + HE+ ++ + E L Sbjct: 3 KNRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREIL 62 Query: 154 ENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 + + E D +G + + +F + + +++ Sbjct: 63 D-----LIDEYDSEGRHLMKYDDFYIVMGEKILKR 92 >5ZOR-A nrPDB Length = 149 Score = 80.2 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 26/161 (16%) Query: 29 LRLHHRFRALDRNKKGYLSRMDL-QQIGALAVNPL----GDRIIESFFPDGSQRVDFPGF 83 ++ F D + G + ++ + L L +R + S + + +++ F Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEF 66 Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 R++ +D ++ AFQL+DLD+ GKIS + +V + + Sbjct: 67 ERMVKSRMAQKD----------------SPEEVLKAFQLFDLDKKGKISFANLKEVAK-L 109 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +G ++ L+ + EADEDGDG VSF EF + +M Sbjct: 110 LGENPGDDVLQE----MIAEADEDGDGEVSFEEFKSVMMQM 146 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 4/96 (4%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGA-LAV 59 M + ++ + + + + + S + F+ D +KKG +S +L+++ L Sbjct: 53 MNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGE 112 Query: 60 NPLGD---RIIESFFPDGSQRVDFPGFVRVLAHFRP 92 NP D +I DG V F F V+ R Sbjct: 113 NPGDDVLQEMIAEADEDGDGEVSFEEFKSVMMQMRG 148 >4N5X-A nrPDB Length = 199 Score = 80.2 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 33/159 (20%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGS----QRV 78 R F+ALDRN G + +LQ+ + L + PLG E F G ++ Sbjct: 17 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGI-PLGQDAEEKIFTTGDVNKDGKL 75 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DF F++ L K+ AF+ D + DGKI E++Q Sbjct: 76 DFEEFMKYL----------------------KDHEKKMKLAFKSLDKNNDGKIEASEIVQ 113 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 L+ + G+ ++E+Q E I +Q D DG V + E+ Sbjct: 114 SLQTL-GLTISEQQAELI----LQSIDVDGTMTVDWNEW 147 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 35/76 (46%), Gaps = 5/76 (6%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 FQ D + DG + E+ + LR + + + ++ D + DG + F EF K Sbjct: 28 FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE-----EKIFTTGDVNKDGKLDFEEFMK 82 Query: 180 SLEKMDVEQKMSIRIL 195 L+ + + K++ + L Sbjct: 83 YLKDHEKKMKLAFKSL 98 Score = 32.0 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 ++ F++LD+N G + + LQ +G + I++S DG+ VD+ + Sbjct: 89 KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWR 148 Query: 85 RVL 87 Sbjct: 149 DYF 151 >4ZCV-A nrPDB Length = 165 Score = 80.2 bits (196), Expect = 6e-16, Method: Composition-based stats. Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 33/159 (20%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGS----QRV 78 R F+ALDRN G + +LQ+ + L + PLG E F G ++ Sbjct: 8 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGI-PLGQDAEEKIFTTGDVNKDGKL 66 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 DF F++ L K+ AF+ D + DGKI E++Q Sbjct: 67 DFEEFMKYL----------------------KDHEKKMKLAFKSLDKNNDGKIEASEIVQ 104 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 L+ + G+ ++E+Q E I +Q D DG V + E+ Sbjct: 105 SLQTL-GLTISEQQAELI----LQSIDVDGTMTVDWNEW 138 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 42/96 (43%), Gaps = 8/96 (8%) Query: 100 TQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADR 159 ++D + +R L FQ D + DG + E+ + LR + + + ++ Sbjct: 2 SEDACQDAEQPTRYETL---FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE-----EK 53 Query: 160 TVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRIL 195 D + DG + F EF K L+ + + K++ + L Sbjct: 54 IFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSL 89 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 ++ F++LD+N G + + LQ +G + I++S DG+ VD+ + Sbjct: 80 KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWR 139 Query: 85 RVL 87 Sbjct: 140 DYF 142 >2LC5-A nrPDB Length = 151 Score = 76.7 bits (187), Expect = 5e-15, Method: Composition-based stats. Identities = 30/168 (17%), Positives = 69/168 (41%), Gaps = 26/168 (15%) Query: 18 RRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGD---RIIESFFPD 73 ++ + F+ D++ L+ +L + AL NP I++ + D Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKD 62 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 S + D F+ ++ + D + AF+++D +++G IS Sbjct: 63 NSGKFDQETFLTIMLEYGQEVDST----------------EDIKKAFEIFDKEKNGYISA 106 Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 E+ VL + G ++TE++++++ E +G ++ +F K + Sbjct: 107 SELKHVLTTL-GEKLTEQEVDDLLKEIGVE-----EGLINVDDFVKLI 148 >5MWC-D nrPDB Length = 311 Score = 76.3 bits (186), Expect = 7e-15, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 5/105 (4%) Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 ++ A + + +L F+ +D D DG I R E ++R + Sbjct: 121 IKGEAQVKGTGFPADGPVMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIR-L 179 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 G Q+T+E D ++D D +G + F EF K +E + + Sbjct: 180 TGEQLTDEDP----DEIFGDSDTDKNGRIDFDEFLKMVENVQLSM 220 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 30/78 (38%), Gaps = 4/78 (5%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF-- 70 DG + S L FR D++ G++ R + I L L D + Sbjct: 135 DGPVMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFG 194 Query: 71 --FPDGSQRVDFPGFVRV 86 D + R+DF F+++ Sbjct: 195 DSDTDKNGRIDFDEFLKM 212 >5H7D-E nrPDB Length = 120 Score = 76.3 bits (186), Expect = 9e-15, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 +V A + D+ +++ + ++ AF L+D D DG I+ E+ V+R + Sbjct: 27 QVAAFISSLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSL- 85 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 G TE +L++ + E D DG+G + F EF + + Sbjct: 86 GQNPTEAELQD----MINEVDADGNGTIDFPEFLTMMAR 120 Score = 69.8 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 27 SLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRVDFPG 82 + F D++ G ++ +L + +L NP +I DG+ +DFP Sbjct: 54 QIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 113 Query: 83 FVRVLAH 89 F+ ++A Sbjct: 114 FLTMMAR 120 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 34/118 (28%), Gaps = 5/118 (4%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 F++ + F + N + + I +L +P + + +Q F Sbjct: 6 FNKETQEASWEIFTLPNLNGRQVAAF-----ISSLLDDPSQSANLLAEAKKLNQIQAFKE 60 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 + E + N +L D D +G I E L ++ Sbjct: 61 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 >2KN2-A nrPDB Length = 92 Score = 74.8 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 25/73 (34%), Positives = 45/73 (61%), Gaps = 5/73 (6%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 +L AF+++D D++G IS E+ V+ + +G ++T+E++E ++EAD DGD Sbjct: 5 TDAEEELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQ----MIKEADLDGD 59 Query: 170 GAVSFVEFTKSLE 182 G V++ EF K + Sbjct: 60 GQVNYEEFVKMMM 72 Score = 40.9 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRVDFPGFV 84 L F+ D+++ GY+S +L+ + L + + I+ DG +V++ FV Sbjct: 9 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 68 Query: 85 RVL 87 +++ Sbjct: 69 KMM 71 >1FW4-A nrPDB Length = 71 Score = 73.6 bits (179), Expect = 5e-14, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 42/72 (58%), Gaps = 5/72 (6%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 ++ AF+++D D +G IS E+ V+ + G ++T+E+ D ++EAD DGD Sbjct: 2 TDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGD 56 Query: 170 GAVSFVEFTKSL 181 G V++ EF + + Sbjct: 57 GQVNYEEFVQMM 68 Score = 39.7 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 4/64 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRIIESFFPDGSQRVDFPGFV 84 + FR D++ GY+S +L+ + L D +I DG +V++ FV Sbjct: 6 EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 65 Query: 85 RVLA 88 +++ Sbjct: 66 QMMT 69 >2BL0-B nrPDB Length = 145 Score = 71.7 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 67/153 (43%), Gaps = 21/153 (13%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLA 88 ++ F+ D++ G +S +L + +L NP + +++ F LA Sbjct: 6 QIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAEL-----NTIKGQLNAKEF--DLA 58 Query: 89 HFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV 148 F+ V + +T + ++ AF+ D + +G I E+ Q+L L +G + Sbjct: 59 TFKTVYRKPIKTP--------TEQSKEMLDAFRALDKEGNGTIQEAELRQLL-LNLGDAL 109 Query: 149 TEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 T ++E + ++E GDGA+++ F L Sbjct: 110 TSSEVEEL----MKEVSVSGDGAINYESFVDML 138 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 13/68 (19%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 + +++ FQ++D D DGK+S E+ LR + G T +L I Sbjct: 1 TASADQIQECFQIFDKDNDGKVSIEELGSALRSL-GKNPTNAELNTI------------K 47 Query: 170 GAVSFVEF 177 G ++ EF Sbjct: 48 GQLNAKEF 55 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 27/66 (40%), Gaps = 4/66 (6%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRVDFP 81 + FRALD+ G + +L+Q + L + +++ G +++ Sbjct: 73 EQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEELMKEVSVSGDGAINYE 132 Query: 82 GFVRVL 87 FV +L Sbjct: 133 SFVDML 138 >5COC-A nrPDB Length = 130 Score = 71.7 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 118 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 119 PEFLTMMARK 128 Score = 67.8 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 30/72 (41%), Gaps = 4/72 (5%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRVDF 80 + + F D++ G ++ +L + +L NP +I DG+ +DF Sbjct: 59 EECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 118 Query: 81 PGFVRVLAHFRP 92 P F+ ++A Sbjct: 119 PEFLTMMARKMK 130 Score = 27.4 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 18/63 (28%), Gaps = 3/63 (4%) Query: 81 PGFVRVLAHFRPVEDEDT---ETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 F + F D E + N +L D D +G I E L Sbjct: 63 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 122 Query: 138 QVL 140 ++ Sbjct: 123 TMM 125 >3JAX-C nrPDB Length = 151 Score = 71.7 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 61/165 (36%), Gaps = 26/165 (15%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESF-----FPDGSQ 76 FS+ F+ DR G + + AL NP +++ + Sbjct: 4 FSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLK 63 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 + F F+ ++ +D+ + +++D + +G + E+ Sbjct: 64 TLKFEQFLPMMQTIAKNKDQGCFEDYVEGL--------------RVFDKEGNGTVMGAEI 109 Query: 137 LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 VL + G ++TEE++E + ED +G +++ E + + Sbjct: 110 RHVLVTL-GEKMTEEEVEQLVAGH-----EDSNGCINYEELVRMV 148 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 3/68 (4%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AFQL+D DGKI + V+R + G T ++ + ++DE + F Sbjct: 11 EFKEAFQLFDRTGDGKILYSQCGDVMRAL-GQNPTNAEVMKVLGNP--KSDEMNLKTLKF 67 Query: 175 VEFTKSLE 182 +F ++ Sbjct: 68 EQFLPMMQ 75 >1W7I-B nrPDB Length = 151 Score = 71.3 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 64/164 (39%), Gaps = 26/164 (15%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESF-----FPDGS 75 F++ L F DR G + + AL NP +++ S Sbjct: 3 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 62 Query: 76 QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHE 135 +RVDF F+ +L + T + F+++D + +GK+ E Sbjct: 63 RRVDFETFLPMLQAVAKNRGQGTYEDYLEG--------------FRVFDKEGNGKVMGAE 108 Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 + VL + G ++TEE++E + ED +G +++ F K Sbjct: 109 LRHVLTTL-GEKMTEEEVETVLAGH-----EDSNGCINYEAFLK 146 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 + AF+L+D DGKI + V+R + G T ++ + ++DE V Sbjct: 10 EEFKEAFELFDRVGDGKILYSQCGDVMRAL-GQNPTNAEVLKVLGNP--KSDELKSRRVD 66 Query: 174 FVEFTKSLEKM 184 F F L+ + Sbjct: 67 FETFLPMLQAV 77 >2KZ2-A nrPDB Length = 94 Score = 70.5 bits (171), Expect = 4e-13, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 41/72 (56%), Gaps = 5/72 (6%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 ++ AF++ D D +G IS E+ V+ + G ++T+E+ D ++EAD DGD Sbjct: 25 TDSEEEIREAFRVEDKDGNGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGD 79 Query: 170 GAVSFVEFTKSL 181 G V++ EF + + Sbjct: 80 GQVNYEEFVQMM 91 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 4/64 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRIIESFFPDGSQRVDFPGFV 84 + FR D++ GY+S +L+ + L D +I DG +V++ FV Sbjct: 29 EEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 88 Query: 85 RVLA 88 +++ Sbjct: 89 QMMT 92 >2K7C-A nrPDB Length = 72 Score = 70.1 bits (170), Expect = 6e-13, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 4/70 (5%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 +L AF+ +D + DG+IS E+ + +R ++G QV +E I +++ D +GDG V Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEI----IRDVDLNGDGRVD 62 Query: 174 FVEFTKSLEK 183 F EF + + + Sbjct: 63 FEEFVRMMSR 72 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 5/67 (7%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG----DRIIESFFPDGSQRVDFPG 82 + L FR D N G +S +L++ + L + +G + II +G RVDF Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 83 FVRVLAH 89 FVR+++ Sbjct: 66 FVRMMSR 72 Score = 26.6 bits (57), Expect = 6.8, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 161 VQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 +E D +GDG +S E +++ K+ Q Sbjct: 13 FREFDTNGDGEISTSELREAMRKLLGHQ 40 >2ROB-A nrPDB Length = 70 Score = 69.8 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 25/72 (34%), Positives = 45/72 (62%), Gaps = 5/72 (6%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 +L AF+++D D++G IS E+ V+ + +G ++T+E++E ++EAD DGDG Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVM-INLGEKLTDEEVEQ----MIKEADLDGDG 55 Query: 171 AVSFVEFTKSLE 182 V++ EF K + Sbjct: 56 QVNYEEFVKMMM 67 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRVDFPGFV 84 L F+ D+++ GY+S +L+ + L + + I+ DG +V++ FV Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 63 Query: 85 RVL 87 +++ Sbjct: 64 KMM 66 >3DTP-E nrPDB Length = 196 Score = 69.8 bits (169), Expect = 8e-13, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 68/162 (41%), Gaps = 22/162 (13%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFP 81 F+Q + F+ +D++K G++S+ D++ ++ ++S + ++F Sbjct: 50 MFTQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAEAPGPINFT 109 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 F+ + DE + + AF L+D + DGK + + L Sbjct: 110 MFLTIFGDRIAGTDE----------------EDVIVNAFNLFD-EGDGKCKEETLKRSLT 152 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 G + ++++ D+ + EA DG+G + +F + L K Sbjct: 153 T-WGEKFSQDE----VDQALSEAPIDGNGLIDIKKFAQILTK 189 >2RO9-A nrPDB Length = 69 Score = 69.8 bits (169), Expect = 8e-13, Method: Composition-based stats. Identities = 24/72 (33%), Positives = 43/72 (59%), Gaps = 5/72 (6%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 +L AF+++D D++G IS E+ V+ + G ++T+E+ D ++EAD DGDG Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNL-GEKLTDEE----VDEMIREADVDGDG 55 Query: 171 AVSFVEFTKSLE 182 +++ EF K + Sbjct: 56 QINYEEFVKVMM 67 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLG---DRIIESFFPDGSQRVDFPGFV 84 L FR D+++ G++S +L+ + L D +I DG ++++ FV Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFV 63 Query: 85 RVL 87 +V+ Sbjct: 64 KVM 66 >2LV7-A nrPDB Length = 100 Score = 69.4 bits (168), Expect = 9e-13, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 V +R + + + + ++ AF+++D D +G IS+ E+ +R + Sbjct: 6 VTAALMYRGIYTVPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSL 65 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 G E +LE I R D DGDG V F EF L Sbjct: 66 -GYMPNEVELEVIIQRL----DMDGDGQVDFEEFVTLL 98 Score = 59.4 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRI 66 +P+ S +R + L + F+ DR+ G++S+ +L + +L P + I Sbjct: 18 VPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVI 77 Query: 67 IESFFPDGSQRVDFPGFVRVLAH 89 I+ DG +VDF FV +L Sbjct: 78 IQRLDMDGDGQVDFEEFVTLLGP 100 >2M5E-A nrPDB Length = 73 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 5/71 (7%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 +L AF+++D D +G IS E+ V+ + G ++T+++ D ++EAD DGDG Sbjct: 5 DSEEELIEAFKVFDRDGNGLISAAELRHVMTNL-GEKLTDDE----VDEMIREADIDGDG 59 Query: 171 AVSFVEFTKSL 181 +++ EF + + Sbjct: 60 HINYEEFVRMM 70 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRI---IESFFPDGSQRVDFPGFV 84 L F+ DR+ G +S +L+ + L D + I DG +++ FV Sbjct: 8 EELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFV 67 Query: 85 RVL 87 R++ Sbjct: 68 RMM 70 >5E37-A nrPDB Length = 356 Score = 67.8 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 69/179 (38%), Gaps = 34/179 (18%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL---------QQIGALAV----NPLGDRIIESF 70 S+A + L RF+ D + G++ R +L ++ ++ +R +E + Sbjct: 24 SKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQY 83 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 + + F F +++ +E E + AF+ D +G Sbjct: 84 DVNKDGVISFEEFKQIIYDGLLLEGTLAEYES----------------AFKAVDKSGNGT 127 Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQK 189 I E+ ++ +G V+ E+L ++ +Q D+D G + F EF ++ K Sbjct: 128 IGATELSKLF-ASLGNPVSLEKLVDL----MQMYDKDDSGQIEFPEFLLMFRNSLLDLK 181 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 97 DTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM----VGVQVTEEQ 152 T + + ++ +L F++ D+D +G I R E+ +L M V + Sbjct: 12 RAATFEGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWL 71 Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSL 181 E+ +R +++ D + DG +SF EF + + Sbjct: 72 PEDELERCMEQYDVNKDGVISFEEFKQII 100 Score = 43.2 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----II 67 + I + + +L F+A+D++ G + +L ++ A NP+ ++ Sbjct: 94 EEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLM 153 Query: 68 ESFFPDGSQRVDFPGFVRVL 87 + + D S +++FP F+ + Sbjct: 154 QMYDKDDSGQIEFPEFLLMF 173 >2I08-A nrPDB Length = 78 Score = 67.4 bits (163), Expect = 4e-12, Method: Composition-based stats. Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF LYD D DG I+ E+ V+R + G+ TE +L++ + E D DG+G + F Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSL-GLNPTEAELQD----MINEVDADGNGTIDF 65 Query: 175 VEFTKSLEKM 184 EF + ++ Sbjct: 66 PEFLTMMARI 75 Score = 66.3 bits (160), Expect = 9e-12, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 4/74 (5%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L +NP +I DG+ + Sbjct: 4 LTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRP 92 DFP F+ ++A Sbjct: 64 DFPEFLTMMARIMK 77 >4Q57-A nrPDB Length = 65 Score = 67.1 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 57 Query: 175 VEFTKSL 181 EF + Sbjct: 58 PEFLTMM 64 Score = 62.0 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRVDFPGF 83 + F D++ G ++ +L + +L NP +I DG+ +DFP F Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 84 VRVLA 88 + ++A Sbjct: 61 LTMMA 65 >2JNX-A nrPDB Length = 134 Score = 66.3 bits (160), Expect = 8e-12, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 60/151 (39%), Gaps = 27/151 (17%) Query: 32 HHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 F+ LD N G +S +++ + L I ++ DG+ +D F Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEF---- 58 Query: 88 AHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ 147 T+ K + L+ + L ++L D D DGK+++ E+ + + Sbjct: 59 ----------TKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGYEK 108 Query: 148 VTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 V ++ + +AD +GDG ++ EF Sbjct: 109 VVDQ---------IMKADANGDGYITLEEFL 130 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 45/121 (37%), Gaps = 19/121 (15%) Query: 63 GDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 + + + +G V + ++ RP+++ L F+ Sbjct: 2 AEALFKQLDANGDGSVSYEEVKAFVSSKRPIKN-----------------EQLLQLIFKA 44 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 D+D +G+I E + + +++E++ + D DGDG ++ E T + Sbjct: 45 IDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVG--LKILYKLMDADGDGKLTKEEVTTFFK 102 Query: 183 K 183 K Sbjct: 103 K 103 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 28/68 (41%), Gaps = 3/68 (4%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGSQR 77 +E S + L ++ +D + G L++ ++ + D+I+++ +G Sbjct: 66 KEQDLSDEKVG-LKILYKLMDADGDGKLTKEEVTTFFKKFGYEKVVDQIMKA-DANGDGY 123 Query: 78 VDFPGFVR 85 + F+ Sbjct: 124 ITLEEFLA 131 Score = 30.5 bits (67), Expect = 0.55, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 33/116 (28%), Gaps = 28/116 (24%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDR------IIESFFPDGSQRVDFP 81 L F+A+D + G + + + A+ L D + + DG ++ Sbjct: 36 QLLQLIFKAIDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKE 95 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 F + D + D + DG I+ E L Sbjct: 96 EVTTFFKKFGYEKVVDQIMKA---------------------DANGDGYITLEEFL 130 Score = 26.6 bits (57), Expect = 6.3, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 15/21 (71%) Query: 156 IADRTVQEADEDGDGAVSFVE 176 +A+ ++ D +GDG+VS+ E Sbjct: 1 MAEALFKQLDANGDGSVSYEE 21 >2RO8-A nrPDB Length = 79 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 65 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 66 PEFLNLMARK 75 Score = 64.4 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 + + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 4 LTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRP 92 DFP F+ ++A Sbjct: 64 DFPEFLNLMARKMK 77 >2BL0-C nrPDB Length = 142 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 24/161 (14%), Positives = 55/161 (34%), Gaps = 26/161 (16%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQI---GALAVNP-LGDRIIESFFPDGSQRVDF 80 + F D + G++++ LQ + + V P + + G+ ++ F Sbjct: 2 DDQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQF 61 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 P F+ ++ + + L AF+ +D + G I + + L Sbjct: 62 PEFLSMMGRRMKQ----------------TTSEDILRQAFRTFDPEGTGYIPKAALQDAL 105 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 L +G ++ + T E G + + F ++ Sbjct: 106 -LNLGDRLKPHEFAEFLGITETE-----KGQIRYDNFINTM 140 Score = 49.7 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 6/82 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF+L+D +R G I++ + VL+ GV+V + EAD G+G + F Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLKQF-GVRVEPAA----FNEMFNEADATGNGKIQF 61 Query: 175 VEFTKSLEKMDVEQKMSIRILK 196 EF + + ++Q S IL+ Sbjct: 62 PEFLSMMGRR-MKQTTSEDILR 82 >3IFK-A nrPDB Length = 90 Score = 65.5 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG---DRIIESFFPDGSQRV 78 ++ + F D++ G ++ +L + +L NP +I DG+ + Sbjct: 4 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 63 Query: 79 DFPGFVRVLAHFRPVEDEDTE 99 DFP F+ ++A D + E Sbjct: 64 DFPEFLTMMARKMKDTDSEEE 84 Score = 62.0 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D DG I+ E+ V+R + G TE +L++ + E D DG+G + F Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSL-GQNPTEAELQD----MINEVDADGNGTIDF 65 Query: 175 VEFTKSLEKM 184 EF + + Sbjct: 66 PEFLTMMARK 75 Score = 28.1 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 24/78 (30%), Gaps = 3/78 (3%) Query: 81 PGFVRVLAHFRPVEDEDT---ETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 F + F D E + N +L D D +G I E L Sbjct: 10 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 138 QVLRLMVGVQVTEEQLEN 155 ++ + +EE++ Sbjct: 70 TMMARKMKDTDSEEEIRE 87 >5TBY-E nrPDB Length = 166 Score = 64.4 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 24/168 (14%), Positives = 56/168 (33%), Gaps = 22/168 (13%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVD 79 + F Q + F +D+N+ G++ + DL+ AL + + I+ + ++ Sbjct: 19 SMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPIN 78 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F F+ + D + AF+++D + G + + ++ Sbjct: 79 FTVFLTMFGEKLKGADP----------------EETILNAFKVFDPEGKGVLKADYVREM 122 Query: 140 LRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVE 187 L EE D+ D G + + + + + Sbjct: 123 LTTQAERFSKEE-----VDQMFAAFPPDVTGNLDYKNLVHIITHGEEK 165 >6IIE-A nrPDB Length = 93 Score = 64.0 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 4/75 (5%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHE----MLQVLRLMVGVQVTEEQLENIADRTVQEAD 165 +KL + F+LYD DR+G + E +LQ++R+ + +L I ++E D Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Query: 166 EDGDGAVSFVEFTKS 180 DG G+VS E+ ++ Sbjct: 65 YDGSGSVSQAEWVRA 79 Score = 28.5 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 28/77 (36%), Gaps = 13/77 (16%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQ-------------IGALAVNPLGDRIIESFFPDGSQ 76 +L F+ D ++ G L ++ + + P+ +++ DGS Sbjct: 10 KLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSG 69 Query: 77 RVDFPGFVRVLAHFRPV 93 V +VR A P+ Sbjct: 70 SVSQAEWVRAGATTVPL 86 >6FSA-D nrPDB Length = 199 Score = 64.0 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 63/168 (37%), Gaps = 28/168 (16%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ---IGALAVNPLGDRIIESF-----F 71 + F+ + F DR K + Q + AL NP ++ Sbjct: 47 KIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQE 106 Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 S+ +DF F+ +L H +D T + +++D + +G + Sbjct: 107 ELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGL--------------RVFDKEGNGTV 152 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 E+ VL + G ++TE+++E + ED +G +++ F K Sbjct: 153 MGAELRHVLATL-GEKLTEDEVEKLMAGQ-----EDSNGCINYEAFVK 194 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 5/86 (5%) Query: 101 QDPKKPEPLNSRRNKLHYAFQLYDL--DRDGKISRHEMLQVLRLMVGVQVTEEQLENIAD 158 K E + + AF L+D + KI+ + VLR + G T+ ++ + Sbjct: 43 PSKIKIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRAL-GQNPTQAEVLRVLG 101 Query: 159 RTVQEADEDGDGAVSFVEFTKSLEKM 184 + QE E + F F L+ + Sbjct: 102 KPKQE--ELNSKMMDFDTFLPMLQHI 125 >2HF5-A nrPDB Length = 68 Score = 62.8 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 16/81 (19%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 +I DG+ +DFP F+ ++A D ++ AF+++ Sbjct: 4 QDMINEVDADGNGTIDFPEFLTMMARKMKDTD----------------SEEEIREAFRVF 47 Query: 124 DLDRDGKISRHEMLQVLRLMV 144 D D +G IS E+ V+ + Sbjct: 48 DKDGNGYISAAELRHVMTNLG 68 Score = 34.3 bits (77), Expect = 0.038, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 124 DLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 D D +G I E L ++ ++ + E + D+DG+G +S E + Sbjct: 11 DADGNGTIDFPEFLTMM----ARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTN 66 Query: 184 M 184 + Sbjct: 67 L 67 Score = 33.2 bits (74), Expect = 0.085, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 13/28 (46%) Query: 157 ADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + E D DG+G + F EF + + Sbjct: 3 LQDMINEVDADGNGTIDFPEFLTMMARK 30 Score = 30.5 bits (67), Expect = 0.50, Method: Composition-based stats. Identities = 8/65 (12%), Positives = 17/65 (26%), Gaps = 5/65 (7%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD-----RIIESFFPDGSQRVDFPGF 83 L +D + G + + + A + F DG+ + Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 84 VRVLA 88 V+ Sbjct: 61 RHVMT 65 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 19/45 (42%) Query: 12 PDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGA 56 P+ ++ S + FR D++ GY+S +L+ + Sbjct: 21 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 65 >3I5H-B nrPDB Length = 153 Score = 62.8 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 57/143 (39%), Gaps = 19/143 (13%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG-ALAVNPLGDRIIESFFPD 73 + R SQ + L F +D+++ G++ DL+ + +L P D + + + Sbjct: 2 EEAPRRVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDEL-NAMLKE 60 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 +++F F+ + D + L AF ++D D G I Sbjct: 61 CPGQLNFTAFLTLFGEKVSGTDP----------------EDALRNAFSMFDEDGQGFIPE 104 Query: 134 HEMLQVLRLMVGVQVTEEQLENI 156 + +L M G ++E+++N+ Sbjct: 105 DYLKDLLENM-GDNFSKEEIKNV 126 >1I84-U nrPDB Length = 166 Score = 62.8 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 55/137 (40%), Gaps = 18/137 (13%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVD 79 + F + + F +D+N G + + DL+ A+ + + +++ + S ++ Sbjct: 17 SMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPIN 76 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F F+ + D + + AF++ D D G I + + ++ Sbjct: 77 FTVFLTMFGEKLKGADP----------------EDVIMGAFKVLDPDGKGSIKKSFLEEL 120 Query: 140 LRLMVGVQVTEEQLENI 156 L G + T E+++N+ Sbjct: 121 LTTGGG-RFTPEEIKNM 136 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 32/90 (35%), Gaps = 8/90 (8%) Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 + + E + AF + D + DG I + ++ + M + V Sbjct: 2 KKAKRRAAEGSSNVFSMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN 61 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTKS 180 E+L D ++EA G ++F F Sbjct: 62 EEL----DAMIKEA----SGPINFTVFLTM 83 >1JFJ-A nrPDB Length = 134 Score = 62.4 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 62/152 (40%), Gaps = 27/152 (17%) Query: 32 HHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 F+ +D N G +S +++ + A+ L I +S DG+ +D F + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 88 AHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ 147 + + D + L ++L D+D DGK+++ E+ + + Sbjct: 63 GSIQGQDLSDDKIG--------------LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEK 108 Query: 148 VTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 V E+ + +AD +GDG ++ EF + Sbjct: 109 VAEQVM---------KADANGDGYITLEEFLE 131 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 49/126 (38%), Gaps = 19/126 (15%) Query: 63 GDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 + + + +G V + ++ R +++ L F+ Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN-----------------EQLLQLIFKS 44 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 D D +G+I ++E + + G ++++++ + D DGDG ++ E T + Sbjct: 45 IDADGNGEIDQNEFAKFYGSIQGQDLSDDKIG--LKVLYKLMDVDGDGKLTKEEVTSFFK 102 Query: 183 KMDVEQ 188 K +E+ Sbjct: 103 KHGIEK 108 Score = 32.4 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 36/117 (30%), Gaps = 28/117 (23%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGA--LAVNPLGDRI-----IESFFPDGSQRVDFP 81 L F+++D + G + + + + + D+I + DG ++ Sbjct: 36 QLLQLIFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKL--- 92 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 E K + ++ A D + DG I+ E L+ Sbjct: 93 --------------TKEEVTSFFKKHGIEKVAEQVMKA----DANGDGYITLEEFLE 131 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 10/21 (47%), Positives = 15/21 (71%) Query: 156 IADRTVQEADEDGDGAVSFVE 176 +A+ +E D +GDGAVS+ E Sbjct: 1 MAEALFKEIDVNGDGAVSYEE 21 Score = 26.2 bits (56), Expect = 8.9, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 20/46 (43%), Gaps = 2/46 (4%) Query: 10 VIPDGDSIRRE--TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ 53 V DG + E + F + + ++ + D N GY++ + + Sbjct: 86 VDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLE 131 >5TBY-C nrPDB Length = 195 Score = 62.0 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 67/175 (38%), Gaps = 28/175 (16%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ---IGALAVNPLGDRIIES 69 + D+ + + F+ + F DR K + Q + AL NP ++ Sbjct: 36 EFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRV 95 Query: 70 F-----FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 ++ +DF F+ +L H +D T + +++D Sbjct: 96 LGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGL--------------RVFD 141 Query: 125 LDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 + +G + E+ VL + G ++TE+++E + ED +G +++ F K Sbjct: 142 KEGNGTVMGAELRHVLATL-GERLTEDEVEKLMAGQ-----EDSNGCINYEAFVK 190 >5H53-C nrPDB Length = 153 Score = 61.7 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 66/172 (38%), Gaps = 26/172 (15%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGS--- 75 + FS+ F DR ++ + + AL NP + + + Sbjct: 2 KIEFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEM 61 Query: 76 --QRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 ++++F F+ +L +D+ T + +++D + +G + Sbjct: 62 NAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGL--------------RVFDKEGNGTVMG 107 Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 E+ VL + G ++ EE++E + ED +G +++ F K + +D Sbjct: 108 AELRHVLATL-GEKMKEEEVEALMAGQ-----EDSNGCINYEAFVKHIMSID 153 >2B1U-A nrPDB Length = 71 Score = 61.3 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 L AF+ +D D DG I+ E+ + + + EE D ++EAD D DG V+ Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEE-----LDAMIREADVDQDGRVN 60 Query: 174 FVEFTKSLEK 183 + EF + L + Sbjct: 61 YEEFARMLAQ 70 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----IIESFFPDGSQRVDFPGF 83 L L FRA D++ G+++ +L++ A PL +I D RV++ F Sbjct: 5 LEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEF 64 Query: 84 VRVLAH 89 R+LA Sbjct: 65 ARMLAQ 70 >2AMI-A nrPDB Length = 96 Score = 61.3 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 5/71 (7%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E D+DG G Sbjct: 27 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRAL-GFEPKKEEIK----KMISEIDKDGSG 81 Query: 171 AVSFVEFTKSL 181 + F EF + Sbjct: 82 TIDFEEFLTMM 92 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 4/81 (4%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESF 70 D + G ++ + F D + G + +L+ + AL P + I I Sbjct: 16 DQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEI 75 Query: 71 FPDGSQRVDFPGFVRVLAHFR 91 DGS +DF F+ ++ Sbjct: 76 DKDGSGTIDFEEFLTMMTAKM 96 Score = 30.5 bits (67), Expect = 0.47, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 21/78 (26%), Gaps = 17/78 (21%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 + F DGS +D + + ++ ++ D Sbjct: 34 EAFDLFDTDGSGTIDAKELKVAM-----------------RALGFEPKKEEIKKMISEID 76 Query: 125 LDRDGKISRHEMLQVLRL 142 D G I E L ++ Sbjct: 77 KDGSGTIDFEEFLTMMTA 94 >1O1A-B nrPDB Length = 145 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 54/135 (40%), Gaps = 18/135 (13%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVDFP 81 F + + F +D+N G + + DL+ A+ + + +++ + S ++F Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPINFT 60 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 F+ + D + + AF++ D D G I + + ++L Sbjct: 61 VFLTMFGEKLKGADP----------------EDVIMGAFKVLDPDGKGSIKKSFLEELLT 104 Query: 142 LMVGVQVTEEQLENI 156 G + T E+++N+ Sbjct: 105 TGGG-RFTPEEIKNM 118 Score = 39.7 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 AF + D + DG I + ++ + M + V E+L D ++EA G ++ Sbjct: 7 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEEL----DAMIKEA----SGPIN 58 Query: 174 FVEFTKS 180 F F Sbjct: 59 FTVFLTM 65 >1GGW-A nrPDB Length = 140 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAH 89 F DR+ G + + + + A NP I VD F++VL Sbjct: 7 YKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAE-ITEIESTLPAEVDMEQFLQVLNR 65 Query: 90 FRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT 149 + + FQ++D D G I E+ VL + G +++ Sbjct: 66 --------------PNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSL-GEKLS 110 Query: 150 EEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 E+++ + + DG V++ +F + + Sbjct: 111 NEEMDELLKGVPVK-----DGMVNYHDFVQMI 137 Score = 31.2 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 26/63 (41%), Gaps = 5/63 (7%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 F+ D++ G + +L+ +G N D +++ P V++ FV Sbjct: 76 EEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGV-PVKDGMVNYHDFV 134 Query: 85 RVL 87 +++ Sbjct: 135 QMI 137 >2KSZ-A nrPDB Length = 76 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 5/69 (7%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 AF L+D D DG I+ E+ V+R + TEE+L++ + E D DG+G + F Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRSL-DQNPTEEELQD----MISEVDADGNGTIEFD 66 Query: 176 EFTKSLEKM 184 EF + K Sbjct: 67 EFLSLMAKK 75 Score = 57.4 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGSQRV 78 S+ ++ F D++ G ++ +L I +L NP + + I DG+ + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 79 DFPGFVRVLA 88 +F F+ ++A Sbjct: 64 EFDEFLSLMA 73 >2N7L-C nrPDB Length = 141 Score = 60.1 bits (144), Expect = 5e-10, Method: Composition-based stats. Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 6/72 (8%) Query: 111 SRRNKLHYAFQLYDLD-RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 ++N+ AF ++ L DG IS E+ +V+R M+G T E+L+ + D E DEDG Sbjct: 30 EQKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGS 84 Query: 170 GAVSFVEFTKSL 181 G V F EF + Sbjct: 85 GTVDFDEFLVMM 96 Score = 50.5 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 36/102 (35%), Gaps = 5/102 (4%) Query: 23 FSQASLLRLHHRFRALD-RNKKGYLSRMDLQQ-IGALAVNPL---GDRIIESFFPDGSQR 77 ++ F + G +S +L + + L NP +I+ DGS Sbjct: 27 LTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 86 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 VDF F+ ++ + E+ Q + ++ L A Sbjct: 87 VDFDEFLVMMVRXMKDDSENLYFQGRRVRISADAMMQALLGA 128 >5OTJ-D nrPDB Length = 110 Score = 60.1 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 6/83 (7%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 + + F+ +D + DGKIS E+ LR + E R + E D DGDG + Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADE------VQRMMAEIDTDGDGFID 56 Query: 174 FVEFTKSLEKMDVEQKMSIRILK 196 F EF K ++ K Sbjct: 57 FNEFISFCNANPGLMKDVAKVFK 79 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 22/59 (37%), Gaps = 3/59 (5%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLG--DRIIESFFPDGSQRVDFPGFVR 85 + F+ D N G +S +L + L R++ DG +DF F+ Sbjct: 4 DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFIS 62 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 24/84 (28%), Gaps = 18/84 (21%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 +RI + F +G ++ L ++ + + Sbjct: 6 ERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEI------------------ 47 Query: 124 DLDRDGKISRHEMLQVLRLMVGVQ 147 D D DG I +E + G+ Sbjct: 48 DTDGDGFIDFNEFISFCNANPGLM 71 Score = 26.6 bits (57), Expect = 7.6, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLE 182 + + +R + D +GDG +S E T +L Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALR 30 >1TRF-A nrPDB Length = 76 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF ++D D G IS E+ V+R M+G T+E+L D ++E DEDG G + F Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEEL----DAIIEEVDEDGSGTIDF 64 Query: 175 VEFTKSL 181 EF + Sbjct: 65 EEFLVMM 71 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 29/75 (38%), Gaps = 4/75 (5%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDR---IIESFFPDGSQR 77 S+ + F D + G +S +L + L NP + IIE DGS Sbjct: 2 FLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGT 61 Query: 78 VDFPGFVRVLAHFRP 92 +DF F+ ++ Sbjct: 62 IDFEEFLVMMVRQMK 76 >2G9B-A nrPDB Length = 263 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 52/165 (31%), Gaps = 21/165 (12%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQI----------GALAVNPLGDRIIESFFPDGSQRVD 79 + + D + GYL +LQ + L ++P ++ + ++ Sbjct: 17 QFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIG 76 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 VL E + ++ YD D G I E+ Sbjct: 77 IVELAHVL--------PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 128 Query: 140 LRLMV---GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 L+ ++ V + +L D ++ D + DG + E + L Sbjct: 129 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 173 Score = 52.8 bits (125), Expect = 8e-08, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 51/140 (36%), Gaps = 21/140 (15%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQ------------QIGALAVNPLGDRIIESFFPDGSQ 76 +R D + G++ +L+ + + D +++ F + Sbjct: 103 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 162 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 +++ R+L + K + + + + AF+LYD D +G I +E+ Sbjct: 163 KLELTEMARLLPV---------QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 213 Query: 137 LQVLRLMVGVQVTEEQLENI 156 +L+ + E + NI Sbjct: 214 DALLKDLCEKNKQELDINNI 233 >2K2A-A nrPDB Length = 70 Score = 59.7 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 5/74 (6%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 + +L AF+LYD + +G IS M ++L ++ E D + E D DG G V Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREIL-----AELDETLSSEDLDAMIDEIDADGSGTV 56 Query: 173 SFVEFTKSLEKMDV 186 F EF + D Sbjct: 57 DFEEFMGVMTGGDE 70 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 4/64 (6%) Query: 29 LRLHHRFRALDRNKKGYLS----RMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 L FR D+ GY+S R L ++ + D +I+ DGS VDF F+ Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 62 Query: 85 RVLA 88 V+ Sbjct: 63 GVMT 66 >1M39-A nrPDB Length = 89 Score = 59.4 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 21/109 (19%) Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 ++F F+ V+ +D + ++ AF+L+D D GKIS + Sbjct: 1 MNFGDFLTVMTQKMSEKDT----------------KEEILKAFKLFDDDETGKISFKNLK 44 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 +V + + G +T+E+L+ + D EAD DGDG VS EF + ++K + Sbjct: 45 RVAKEL-GENLTDEELQEMID----EADRDGDGEVSEQEFLRIMKKTSL 88 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLG---DRIIESFFPDGSQRVDF 80 + + + F+ D ++ G +S +L+++ L N +I+ DG V Sbjct: 17 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSE 76 Query: 81 PGFVRVL 87 F+R++ Sbjct: 77 QEFLRIM 83 >1SR6-C nrPDB Length = 156 Score = 59.4 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 58/162 (35%), Gaps = 23/162 (14%) Query: 23 FSQASLLRLHHRFRALD--RNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPD--GSQR 77 SQ + L F D + G + L + L +NP + + G + Sbjct: 3 LSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFAVGGTHKMGEKS 62 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 + F F+ E AF+ +D + G IS E+ Sbjct: 63 LPFEEFLPAYEGLMDCEQGTFADY---------------MEAFKTFDREGQGFISGAELR 107 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 VL + G ++++E ++ I + + ED +G V + +F K Sbjct: 108 HVLTAL-GERLSDEDVDEIIK--LTDLQEDLEGNVKYEDFVK 146 >3AAJ-A nrPDB Length = 167 Score = 59.4 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 32/156 (20%), Positives = 62/156 (39%), Gaps = 35/156 (22%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQIGALA----VNP-LGDRIIESFFPDGSQRVDFPGFVR 85 L + F+ +D+++ G +S +LQQ + NP II F + V+F F Sbjct: 6 LWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFT- 64 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG 145 ++ + D F+ YD D G I ++E+ Q + G Sbjct: 65 --GVWKYITDWQNV--------------------FRTYDRDNSGMIDKNELKQ---ALSG 99 Query: 146 VQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 ++++ D +++ D G G ++F +F + Sbjct: 100 YRLSD----QFHDILIRKFDRQGRGQIAFDDFIQGC 131 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 39/106 (36%), Gaps = 25/106 (23%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQI--GALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 + + FR DR+ G + + +L+Q G + D +I F G ++ F F++ Sbjct: 70 ITDWQNVFRTYDRDNSGMIDKNELKQALSGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQ 129 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 + + D F+ YD D+DG I Sbjct: 130 GCIVLQRLTDI-----------------------FRRYDTDQDGWI 152 >1TNP-A nrPDB Length = 90 Score = 59.4 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF ++D D G IS E+ V+R M+G T+E+L D ++E DEDG G + F Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMR-MLGQNPTKEEL----DAIIEEVDEDGSGTIDF 75 Query: 175 VEFTKSL 181 EF + Sbjct: 76 EEFLVMM 82 Score = 59.0 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 29/83 (34%), Gaps = 4/83 (4%) Query: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDR---IIESF 70 S+ + F D + G +S +L + L NP + IIE Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEV 65 Query: 71 FPDGSQRVDFPGFVRVLAHFRPV 93 DGS +DF F+ ++ Sbjct: 66 DEDGSGTIDFEEFLVMMVRQMKE 88 >5VLN-A nrPDB Length = 120 Score = 59.0 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 6/72 (8%) Query: 111 SRRNKLHYAFQLYDLD-RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 ++N+ AF ++ L DG IS E+ +V+R M+G T E+L+ + D E DEDG Sbjct: 15 EQKNEFKAAFDIFVLGAEDGSISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGS 69 Query: 170 GAVSFVEFTKSL 181 G V F EF + Sbjct: 70 GTVDFDEFLVMM 81 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 27/75 (36%), Gaps = 5/75 (6%) Query: 23 FSQASLLRLHHRFRALD-RNKKGYLSRMDLQQ-IGALAVNPL---GDRIIESFFPDGSQR 77 ++ F + G +S +L + + L NP +I+ DGS Sbjct: 12 LTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 71 Query: 78 VDFPGFVRVLAHFRP 92 VDF F+ ++ Sbjct: 72 VDFDEFLVMMVRSMK 86 >1B7T-Y nrPDB Length = 156 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 28/168 (16%), Positives = 62/168 (36%), Gaps = 22/168 (13%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDF 80 T Q + + F +D ++ G++S+ D++ I D+ + + + ++F Sbjct: 10 TKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEAPGPLNF 69 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 F+ + + D + AF ++D K++ + +L Sbjct: 70 TMFLSIFSDKLSGTD----------------SEETIRNAFAMFDEQETKKLNIEYIKDLL 113 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 M +E T +EA +G G +V+FT ++ E+ Sbjct: 114 ENMGDNFNKDE-----MRMTFKEAPVEG-GKFDYVKFTAMIKGSGEEE 155 >2OS8-B nrPDB Length = 157 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 59/162 (36%), Gaps = 22/162 (13%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDF 80 T Q + + F +D+N+ G++ DL+++ + D+ + + + ++F Sbjct: 11 TKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNF 70 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 F+ + + D + AF ++D K++ + +L Sbjct: 71 TMFLSIFSDKLSGTD----------------SEETIRNAFGMFDELDTKKLNIEYIKDLL 114 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 M +E T +EA +G G +V F ++ Sbjct: 115 ENMGDNFNKDE-----MRMTFKEAPVEG-GKFDYVRFVAMIK 150 >1JC2-A nrPDB Length = 76 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 5/80 (6%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 + +L F+++D + DG I E+ ++LR G V EE +E++ ++++ Sbjct: 1 MEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRA-TGEHVIEEDIEDL----MKDS 55 Query: 165 DEDGDGAVSFVEFTKSLEKM 184 D++ DG + F EF K +E + Sbjct: 56 DKNNDGRIDFDEFLKMMEGV 75 Score = 33.5 bits (75), Expect = 0.062, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF----FPDGSQRVDFPGFV 84 L + FR D+N G++ +L +I + + IE + R+DF F+ Sbjct: 10 EELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFL 69 Query: 85 RVL 87 +++ Sbjct: 70 KMM 72 >1N2D-A nrPDB Length = 148 Score = 57.8 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 25/149 (16%), Positives = 59/149 (39%), Gaps = 13/149 (8%) Query: 32 HHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHF 90 F D+ +G +++ L + A+ NP + + D S R + Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLR-------DASSLT 59 Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 E + + ++ AFQ++D + GK+S ++ +L + G ++T+ Sbjct: 60 LDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGL-GEKLTD 118 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTK 179 + D ++ + D +G + + +F + Sbjct: 119 AE----VDELLKGVEVDSNGEIDYKKFIE 143 Score = 33.9 bits (76), Expect = 0.051, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 26/66 (39%), Gaps = 4/66 (6%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLG---DRIIESFFPDGSQRVD 79 ++A F+ D+ G +S DL+ + L D +++ D + +D Sbjct: 78 TKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEID 137 Query: 80 FPGFVR 85 + F+ Sbjct: 138 YKKFIE 143 >3E3R-A nrPDB Length = 204 Score = 57.8 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 33/157 (21%), Positives = 58/157 (36%), Gaps = 24/157 (15%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQ----IGALAVNPLGDRIIESFFPDGSQRVDFPGF 83 + L FR LDR+ L + +Q +G + + + + +GS +D F Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEF 95 Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL--R 141 +R L +P +R + AF D DG ++ ++ V R Sbjct: 96 LRAL-----------------RPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGR 138 Query: 142 LMVGVQVTEEQLENIADRTVQEAD-EDGDGAVSFVEF 177 V+ E + + R + D + DG V+ EF Sbjct: 139 AHPKVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEF 175 Score = 40.9 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 28/63 (44%), Gaps = 5/63 (7%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+ D D + E Q L + G+ + + + E + ++ D +G G + EF + Sbjct: 43 FRQLDRDGSRSLDADEFRQGLAKL-GLVLDQAEAEGVC----RKWDRNGSGTLDLEEFLR 97 Query: 180 SLE 182 +L Sbjct: 98 ALR 100 Score = 34.7 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 31/97 (31%), Gaps = 12/97 (12%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNP-------LGDRIIESF----- 70 SQA + F LDR+ G ++ DL+ + + +P D ++ F Sbjct: 103 MSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD 162 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPE 107 + +V F + + D E Sbjct: 163 SSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMTSA 199 Score = 26.6 bits (57), Expect = 8.0, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 14/26 (53%) Query: 159 RTVQEADEDGDGAVSFVEFTKSLEKM 184 R ++ D DG ++ EF + L K+ Sbjct: 41 RFFRQLDRDGSRSLDADEFRQGLAKL 66 >2K2I-A nrPDB Length = 79 Score = 57.8 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 5/82 (6%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 + + ++ AF+L+D D GKIS + +V + + G +T+E+L+ + D EA Sbjct: 2 QKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL-GENLTDEELQEMID----EA 56 Query: 165 DEDGDGAVSFVEFTKSLEKMDV 186 D DGDG VS EF + ++K + Sbjct: 57 DRDGDGEVSEQEFLRIMKKTSL 78 Score = 30.8 bits (68), Expect = 0.40, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLG---DRIIESFFPDGSQRVDF 80 + + + F+ D ++ G +S +L+++ L N +I+ DG V Sbjct: 7 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSE 66 Query: 81 PGFVRVL 87 F+R++ Sbjct: 67 QEFLRIM 73 >1JF0-A nrPDB Length = 195 Score = 57.8 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 66/178 (37%), Gaps = 26/178 (14%) Query: 17 IRRETGFSQAS-LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPL----------GDR 65 ++ +T F + R F LD N G ++ ++ + + Sbjct: 7 VKLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQD 66 Query: 66 IIESFFP----DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQ 121 +E+FF + + FP F+ ++ + + D +P + + + F Sbjct: 67 CVEAFFRGCGLEYGKETKFPEFLEG---WKNLANADLAKWARNEPTLIREWGDAV---FD 120 Query: 122 LYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 ++D D G I+ E R + G+ +EE E +T Q D D G + E T+ Sbjct: 121 IFDKDGSGTITLDEWKAYGR-ISGISPSEEDCE----KTFQHCDLDNSGELDVDEMTR 173 >5H53-B nrPDB Length = 146 Score = 56.7 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 54/133 (40%), Gaps = 18/133 (13%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIESFFPDGSQRVDFPGF 83 Q + F +D+N+ G + + DL+ A+ + + +++ + S ++F F Sbjct: 1 QTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEASGPINFTVF 60 Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 + + D + + AF++ D + G I + + ++L Sbjct: 61 LTMFGEKLKGADP----------------EDVITGAFKVLDPEGKGTIKKQFLEELLITQ 104 Query: 144 VGVQVTEEQLENI 156 + ++E+++N+ Sbjct: 105 CD-RFSQEEIKNM 116 Score = 40.1 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ + AF + D +RDG I + ++ M + V E+L D ++EA G Sbjct: 2 TQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEEL----DAMMKEA----SG 53 Query: 171 AVSFVEFTKS 180 ++F F Sbjct: 54 PINFTVFLTM 63 >2W4G-C nrPDB Length = 145 Score = 56.7 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 25/160 (15%), Positives = 55/160 (34%), Gaps = 26/160 (16%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIESF-----FPDGSQRVD 79 + F DR ++ + I AL NP I + ++++ Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKIT 60 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F F+ +L +D+ T + +++D + +G + E+ V Sbjct: 61 FEEFLPMLQAAANNKDQGTFEDFVEGL--------------RVFDKEGNGTVMGAELRHV 106 Query: 140 LRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 L + E++ + + ED +G +++ F K Sbjct: 107 LATLG------EKMTEEEVEELMKGQEDSNGCINYEAFVK 140 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 N AF L+D D KI+ ++ ++R + G T ++ I +E E ++ Sbjct: 4 NDFKEAFLLFDRTGDAKITLSQVGDIVRAL-GQNPTNAEINKILGNPSKE--EMNAKKIT 60 Query: 174 FVEFTKSLE 182 F EF L+ Sbjct: 61 FEEFLPMLQ 69 >1F55-A nrPDB Length = 77 Score = 56.3 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + AF L+D D +G IS E+ V+R + G+ +E ++ ++ + E D DG+ + F Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSL-GLSPSEAEVNDL----MNEIDVDGNHQIEF 65 Query: 175 VEFTKSLEK 183 EF + + Sbjct: 66 SEFLALMSR 74 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRI---IESFFPDGS 75 + ++ + F D++ G +S +L + +L ++P + + DG+ Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGN 60 Query: 76 QRVDFPGFVRVLAHFRP 92 +++F F+ +++ Sbjct: 61 HQIEFSEFLALMSRQLK 77 >2LVK-A nrPDB Length = 77 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 6/68 (8%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 + + F+ +D + DGKIS E+ LR + E R + E D DGDG + Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADE------VQRMMAEIDTDGDGFID 55 Query: 174 FVEFTKSL 181 F EF Sbjct: 56 FNEFISFC 63 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 22/59 (37%), Gaps = 3/59 (5%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLG--DRIIESFFPDGSQRVDFPGFVR 85 + F+ D N G +S +L + L R++ DG +DF F+ Sbjct: 3 DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFIS 61 Score = 27.0 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 24/84 (28%), Gaps = 18/84 (21%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 +RI + F +G ++ L ++ + + Sbjct: 5 ERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEI------------------ 46 Query: 124 DLDRDGKISRHEMLQVLRLMVGVQ 147 D D DG I +E + G+ Sbjct: 47 DTDGDGFIDFNEFISFCNANPGLM 70 >2M97-A nrPDB Length = 69 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 5/73 (6%) Query: 112 RRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGA 171 +L F+++D D +G I R E ++R + G Q+T+E D ++D D +G Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIR-LTGEQLTDED----VDEIFGDSDTDKNGR 55 Query: 172 VSFVEFTKSLEKM 184 + F EF K +E + Sbjct: 56 IDFDEFLKMMENV 68 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF----FPDGSQRVDFPGFV 84 L FR D++ G++ R + I L L D ++ D + R+DF F+ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFL 62 Query: 85 RVL 87 +++ Sbjct: 63 KMM 65 >4GJF-A nrPDB Length = 89 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 6/72 (8%) Query: 111 SRRNKLHYAFQLYDLD-RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 ++N+ AF ++ DG IS E+ +V+R M+G T E+L+ + D E DEDG Sbjct: 15 EQKNEFKAAFDIFVQGAEDGCISTKELGKVMR-MLGQNPTPEELQEMID----EVDEDGS 69 Query: 170 GAVSFVEFTKSL 181 G V F EF + Sbjct: 70 GTVDFDEFLVMM 81 Score = 46.3 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 23 FSQASLLRLHHRFRALDRN-KKGYLSRMDLQQ-IGALAVNPL---GDRIIESFFPDGSQR 77 ++ F + + G +S +L + + L NP +I+ DGS Sbjct: 12 LTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGT 71 Query: 78 VDFPGFVRVLAH 89 VDF F+ ++ Sbjct: 72 VDFDEFLVMMVR 83 >1DFK-Y nrPDB Length = 139 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 59/160 (36%), Gaps = 22/160 (13%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPG 82 Q + + F +D ++ G++S+ D++ I D+ + + + ++F Sbjct: 1 LPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEAPGPLNFTM 60 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ + + D + AF ++D K++ + +L Sbjct: 61 FLSIFSDKLSGTD----------------SEETIRNAFAMFDEQETKKLNIEYIKDLLEN 104 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 M +E T +EA +G G +V+FT ++ Sbjct: 105 MGDNFNKDE-----MRMTFKEAPVEG-GKFDYVKFTAMIK 138 >1H4B-A nrPDB Length = 84 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 F+ +D + DGKIS E+ + L+ + + E + E D DGDG +SF EFT Sbjct: 15 FKRFDANGDGKISAAELGEALKTLGSITPDE------VKHMMAEIDTDGDGFISFQEFT 67 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 19/61 (31%), Gaps = 3/61 (4%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALA--VNPLGDRIIESFFPDGSQRVDFPG 82 F+ D N G +S +L + + L ++ DG + F Sbjct: 6 QDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEIDTDGDGFISFQE 65 Query: 83 F 83 F Sbjct: 66 F 66 Score = 27.8 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 25/83 (30%), Gaps = 18/83 (21%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 +RI + F +G ++ L + ++ + + Sbjct: 12 ERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEI------------------ 53 Query: 124 DLDRDGKISRHEMLQVLRLMVGV 146 D D DG IS E R G+ Sbjct: 54 DTDGDGFISFQEFTDFGRANRGL 76 >3I5I-C nrPDB Length = 159 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 61/162 (37%), Gaps = 18/162 (11%) Query: 21 TGFSQASLLRLHHRFRALD--RNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPDGSQR 77 + ++ + + F D + G + + + L +NP G Sbjct: 1 SQLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEA----QVHQHGG-- 54 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 + + +E + + + ++ AF+ +D + G IS E+ Sbjct: 55 ------TKKMGEKAYKLEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIR 108 Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 VL+ M+G ++TE+Q +I T + ED DG + + + K Sbjct: 109 NVLK-MLGERITEDQCNDIF--TFCDIREDIDGNIKYEDLMK 147 >2OPO-A nrPDB Length = 86 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 F+ +D + DGKIS E+ L+ + V E R + E D DGDG +SF EFT Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLGSVTPDE------VRRMMAEIDTDGDGFISFDEFT 69 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 21/63 (33%), Gaps = 3/63 (4%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALA--VNPLGDRIIESFFPDGSQRVDF 80 + + F+ D N G +S +L + L R++ DG + F Sbjct: 6 TPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGDGFISF 65 Query: 81 PGF 83 F Sbjct: 66 DEF 68 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 24/83 (28%), Gaps = 18/83 (21%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 +RI + F +G ++ L V ++ + Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEI------------------ 55 Query: 124 DLDRDGKISRHEMLQVLRLMVGV 146 D D DG IS E R G+ Sbjct: 56 DTDGDGFISFDEFTDFARANRGL 78 >1OQP-A nrPDB Length = 77 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 R ++ AF+L+D D G I+ ++ +V + + G +TEE+L+ + EAD + D Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKDLRRVAKEL-GENLTEEELQE----MIAEADRNDDN 60 Query: 171 AVSFVEFTKSLEKMDV 186 + EF + ++K + Sbjct: 61 EIDEDEFIRIMKKTSL 76 Score = 30.5 bits (67), Expect = 0.56, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 25/63 (39%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLG---DRIIESFFPDGSQRVDFPGFV 84 + FR D + G ++ DL+++ L N +I + +D F+ Sbjct: 9 EEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFI 68 Query: 85 RVL 87 R++ Sbjct: 69 RIM 71 >3KPX-A nrPDB Length = 198 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 67/178 (37%), Gaps = 26/178 (14%) Query: 17 IRRETGFSQAS-LLRLHHRFRALDRNKKGYLSRMDLQQIGA------LAVNPLG----DR 65 ++ +T F + R F LD N G ++ ++ + L P Sbjct: 10 VKLKTNFEDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQE 69 Query: 66 IIESFFP----DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQ 121 +E+FF D + V+FP FV ++ + D + K + + + F Sbjct: 70 AVEAFFKKIGLDYGKEVEFPAFVNG---WKELAKHDLKLWSQNKKSLIRNWGEAV---FD 123 Query: 122 LYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 ++D D G IS E + G+ ++E E +T + D D G + E T+ Sbjct: 124 IFDKDGSGSISLDEWKT-YGGISGICPSDEDAE----KTFKHCDLDNSGKLDVDEMTR 176 >1S36-A nrPDB Length = 195 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 57/178 (32%), Gaps = 26/178 (14%) Query: 17 IRRETGFSQ-ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRI--------- 66 ++ +T F + R H F LD N G ++ ++ + + + Sbjct: 7 VKLKTDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQV 66 Query: 67 -IESFF----PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQ 121 +E+FF + + + FP F+ E + +P F Sbjct: 67 CVEAFFRGCGMEYGKEIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAV------FD 120 Query: 122 LYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 ++D D G I+ E G + + T + D D G + E T+ Sbjct: 121 IFDKDGSGTITLDE-----WKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTR 173 >1ZMZ-A nrPDB Length = 98 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 4/92 (4%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPL 62 + ++ A + + ++ + F D + G + +L+ + AL P Sbjct: 6 KKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPK 65 Query: 63 GDRI---IESFFPDGSQRVDFPGFVRVLAHFR 91 + I I +G+ +++F F+ V+ Sbjct: 66 KEEIKKMISEIDKEGTGKMNFGDFLTVMTQKM 97 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 48/101 (47%), Gaps = 7/101 (6%) Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNK--LHYAFQLYDLDRDGKISRHEMLQVLRLM 143 + ++F+ + + P+P + K + AF L+D D G I E+ +R + Sbjct: 1 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL 60 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 G + +E+++ + + E D++G G ++F +F + + Sbjct: 61 -GFEPKKEEIK----KMISEIDKEGTGKMNFGDFLTVMTQK 96 >5B7X-A nrPDB Length = 156 Score = 54.0 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 19/154 (12%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 ++ F DR+ G + L + +L P D + F Sbjct: 13 QKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYI----------KEFAIEG 62 Query: 88 AHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ 147 F+ + E ++ KP+ +R KL AF+++D D+DGKI ++ L VG + Sbjct: 63 ETFQIEQFELIMEREQSKPD---TREIKLRKAFEVFDQDKDGKIKASDLAHNLTT-VGDK 118 Query: 148 VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 +T+E++E + + D + F K + Sbjct: 119 MTKEEVEKVFSILGITMESD----IDLATFLKLV 148 >2M8U-A nrPDB Length = 77 Score = 54.0 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 5/64 (7%) Query: 118 YAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 AF+++D D +G ++ + +VL + + +E + + EAD G V + F Sbjct: 15 EAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADE-----IEEMIYEADPQNSGYVQYETF 69 Query: 178 TKSL 181 L Sbjct: 70 VGML 73 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLS----RMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 ++ F+ DR+ GY++ R L ++G + + +I P S V + FV Sbjct: 11 AQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYETFV 70 Query: 85 RVL 87 +L Sbjct: 71 GML 73 >3TS5-B nrPDB Length = 161 Score = 53.2 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 25/161 (15%), Positives = 58/161 (36%), Gaps = 22/161 (13%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFP 81 Q + + F +D+N+ G++ DL+++ + D+ + + + ++F Sbjct: 16 RLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNFT 75 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 F+ + + D + AF ++D K++ + +L Sbjct: 76 MFLSIFSDKLSGTD----------------SEETIRNAFGMFDELDTKKLNIEYIKDLLE 119 Query: 142 LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 M +E T +EA +G G +V F ++ Sbjct: 120 NMGDNFNKDE-----MRMTFKEAPVEG-GKFDYVRFVAMIK 154 >1YX7-A nrPDB Length = 83 Score = 53.2 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-VTEEQLENIADRTVQEADEDGD 169 + +L AF+ D + DG ++ E+ + + + +++++++ + + ++ AD++ D Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD 63 Query: 170 GAVSFVEFT 178 G +S EF Sbjct: 64 GKISKEEFL 72 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%), Gaps = 10/73 (13%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQ----------IGALAVNPLGDRIIESFFPDGSQRV 78 L F+ LD N GY++ ++LQ + V ++I+ + ++ Sbjct: 7 AELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKI 66 Query: 79 DFPGFVRVLAHFR 91 F+ A Sbjct: 67 SKEEFLNANAELL 79 >2EC6-B nrPDB Length = 133 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 57/155 (36%), Gaps = 22/155 (14%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 + + F +D+N+ G++ DL++ + D+ + + + ++F F+ + Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAMLKEAPGPLNFTMFLSIF 60 Query: 88 AHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ 147 + D + AF ++D D K++ + +L M Sbjct: 61 SDKLSGTD----------------SEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNF 104 Query: 148 VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 +E T +EA +G G +V F ++ Sbjct: 105 NKDE-----MRMTFKEAPVEG-GKFDYVRFVAMIK 133 >5JOJ-A nrPDB Length = 97 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF D D +G IS +E+ + + + I + + D D DG +SF Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYR-VREITENLMATGDLDQDGRISF 71 Query: 175 VEFTKS 180 EF K Sbjct: 72 DEFIKI 77 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 8/72 (11%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF--------FPDGS 75 S ++ L F +D + GY+S +L + A PL + D Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQD 66 Query: 76 QRVDFPGFVRVL 87 R+ F F+++ Sbjct: 67 GRISFDEFIKIF 78 Score = 30.1 bits (66), Expect = 0.68, Method: Composition-based stats. Identities = 17/106 (16%), Positives = 33/106 (31%), Gaps = 22/106 (20%) Query: 43 KGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQD 102 +G +S ++ ++ DG+ + F + + Sbjct: 3 RGSVSDEEMMELR---------EAFAKVDTDGNGYISFNEL-------------NDLFKA 40 Query: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV 148 P P R DLD+DG+IS E +++ + V Sbjct: 41 ACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDV 86 >5JOL-A nrPDB Length = 82 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +L AF D D +G IS +E+ + + + I + + D D DG +SF Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYR-VREITENLMATGDLDQDGRISF 71 Query: 175 VEFTKS 180 EF K Sbjct: 72 DEFIKI 77 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 8/72 (11%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF--------FPDGS 75 S ++ L F +D + GY+S +L + A PL + D Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQD 66 Query: 76 QRVDFPGFVRVL 87 R+ F F+++ Sbjct: 67 GRISFDEFIKIF 78 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 32/101 (31%), Gaps = 22/101 (21%) Query: 43 KGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQD 102 +G +S ++ ++ DG+ + F + + Sbjct: 3 RGSVSDEEMMELR---------EAFAKVDTDGNGYISFNEL-------------NDLFKA 40 Query: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 P P R DLD+DG+IS E +++ + Sbjct: 41 ACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGL 81 >1C7W-A nrPDB Length = 81 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 ++ AF+++D + DG I E +++ + +T+ ++E ++EADEDG+G + Sbjct: 7 EEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEE----AMKEADEDGNGVI 62 Query: 173 SFVEFTKSLEK 183 EF ++K Sbjct: 63 DIPEFMDLIKK 73 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 5/64 (7%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGA-LAVNPLGD----RIIESFFPDGSQRVDFPGF 83 + F+ D N G + + + I + PL D ++ DG+ +D P F Sbjct: 8 EEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 84 VRVL 87 + ++ Sbjct: 68 MDLI 71 Score = 30.8 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 18/37 (48%) Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVE 187 + E R + D +GDG + F EF ++K+ E Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEE 40 Score = 29.7 bits (65), Expect = 0.86, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 26/78 (33%), Gaps = 16/78 (20%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 R + F +G +DF F ++ D E ++ K D Sbjct: 12 RAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEA----------------D 55 Query: 125 LDRDGKISRHEMLQVLRL 142 D +G I E + +++ Sbjct: 56 EDGNGVIDIPEFMDLIKK 73 >2K7B-A nrPDB Length = 76 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRIIE---SFFPDGSQRVDFP 81 + L FR D++K GY++ DL + + P +IE + VDF Sbjct: 7 EEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFD 66 Query: 82 GFVRVLAHFR 91 FV ++ Sbjct: 67 DFVELMGPKL 76 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 5/68 (7%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 +L AF+ +D D+DG I+ ++ +R M G TE +L ++ Q+ + + G V Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTM-GYMPTEMELIELS----QQINMNLGGHVD 64 Query: 174 FVEFTKSL 181 F +F + + Sbjct: 65 FDDFVELM 72 >1OZS-A nrPDB Length = 73 Score = 51.3 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 40/77 (51%), Gaps = 5/77 (6%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 +L F+++D + DG I E+ ++ G +TE+ +E + +++ D++ Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELK-IMLQATGETITEDDIEEL----MKDGDKNN 56 Query: 169 DGAVSFVEFTKSLEKMD 185 DG + + EF + ++ ++ Sbjct: 57 DGRIDYDEFLEFMKGVE 73 Score = 33.9 bits (76), Expect = 0.039, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 26/63 (41%), Gaps = 4/63 (6%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDG----SQRVDFPGFV 84 L FR D+N GY+ +L+ + + + IE DG R+D+ F+ Sbjct: 7 EELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFL 66 Query: 85 RVL 87 + Sbjct: 67 EFM 69 >1Q80-A nrPDB Length = 174 Score = 50.9 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 62/156 (39%), Gaps = 14/156 (8%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQI--GALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 + ++ F +D +K G ++RMD + + + + + + D F+ Sbjct: 5 VQKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWD--NFLT 62 Query: 86 VLAHFRPVEDED---TETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 +A + +++ + + K PE + L F+ D + D ISR E + Sbjct: 63 AVAGGKGIDETTFINSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYG-IFFG 121 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 M+G+ T +A + D + DG +S EF Sbjct: 122 MLGLDKT------MAPASFDAIDTNNDGLLSLEEFV 151 >3JBH-C nrPDB Length = 156 Score = 50.1 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 59/160 (36%), Gaps = 22/160 (13%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIE--SFFPDGSQRVD 79 A + + F D +G + DL + +L P + + G +++ Sbjct: 4 LKAAEVEKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNGGSDKRGEKKLT 63 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F+ + + + ++ T ++YD +G + E+ V Sbjct: 64 LEEFLPIFSQIKKEKEVGTL--------------EDFMEGLKVYDKAENGTMLAAELAHV 109 Query: 140 LRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 L + G ++T+ + E I ++ DED DG + + F K Sbjct: 110 LLSL-GERLTDIECEEI----MRVCDEDDDGFLKYEPFVK 144 Score = 32.8 bits (73), Expect = 0.090, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 K F++YD + +GKI ++ +LR + + T ++ +D+ G+ ++ Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRSL-DCKPTLAMVKKNGG-----SDKRGEKKLT 63 Query: 174 FVEFTKSLEKMDVEQKM 190 EF ++ E+++ Sbjct: 64 LEEFLPIFSQIKKEKEV 80 >2Q4U-A nrPDB Length = 272 Score = 49.7 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 26/175 (14%), Positives = 62/175 (35%), Gaps = 15/175 (8%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDL-----QQIGALA-----VNPLGDRIIES 69 ++ F+ ++ D + GY+ +L + L + +I +S Sbjct: 2 DSAFANLDAAGFLQIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKS 61 Query: 70 FFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDG 129 F F G +++ + ++ + E + ++ YD D G Sbjct: 62 FMSAYDAT--FDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSG 119 Query: 130 KISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 IS E+ L+ + ++ +L+ D ++ D++ DG + + + L Sbjct: 120 YISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARIL 174 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 59/162 (36%), Gaps = 20/162 (12%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQ------------QIGALAVNPLGDRIIESFFPDGSQR 77 +R D + GY+S +L+ +I ++ D +++ F + R Sbjct: 105 EFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGR 164 Query: 78 VDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEML 137 +D R+LA E+ Q R+ F YD+ R G + E+ Sbjct: 165 LDLNDLARILA-----LQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVD 219 Query: 138 QVLRLMVGV---QVTEEQLENIADRTVQEADEDGDGAVSFVE 176 ++ M+ + ++ L+ + + D + DG + E Sbjct: 220 GFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSE 261 Score = 30.1 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 17/113 (15%) Query: 36 RALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDF-PGFVRVLAHFRPVE 94 + D+NK G L DL +I AL N L F D S +V+ F ++ AH+ Sbjct: 155 KIFDKNKDGRLDLNDLARILALQENFLL-----QFKMDASSQVERKRDFEKIFAHYDVSR 209 Query: 95 DEDTETQDP----------KKPEPLNSRRNKLHYAFQLY-DLDRDGKISRHEM 136 E + +P +K + D+++DGKI + E+ Sbjct: 210 TGALEGPEVDGFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSEL 262 >1QX2-A nrPDB Length = 76 Score = 49.0 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 111 SRRNKLHYAFQLYD-LDRD-GKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 ++ AF+++ + D +IS+ E+ V++ + + + + D ++E D++G Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLG---PSLLKGMSTLDEMIEEVDKNG 58 Query: 169 DGAVSFVEFTKSLEKM 184 DG VSF EF ++K+ Sbjct: 59 DGEVSFEEFLVMMKKI 74 Score = 35.1 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 26/70 (37%), Gaps = 7/70 (10%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGA------LAVNPLGDRIIESFFPDGSQR 77 S + F A + + +S+ +L+ + L D +IE +G Sbjct: 3 SPEEIKGAFEVFAAKEGDPN-QISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGE 61 Query: 78 VDFPGFVRVL 87 V F F+ ++ Sbjct: 62 VSFEEFLVMM 71 >1SJJ-A nrPDB Length = 863 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 43/125 (34%), Gaps = 21/125 (16%) Query: 18 RRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVN---PLGDRIIESFFPD 73 R G SQ + F DR K G + D + + ++ N RI+ P+ Sbjct: 714 RDAKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPN 773 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 V F F+ ++ +++ +F++ D++ I+ Sbjct: 774 RMGVVTFQAFIDFMSR----------------ETADTDTADQVMASFKILAGDKN-YITV 816 Query: 134 HEMLQ 138 E+ + Sbjct: 817 DELRR 821 Score = 32.4 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 33/93 (35%), Gaps = 5/93 (5%) Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 R + + + + + N+ +F +D + G + + L M G + E Sbjct: 702 RTINEVENQILTRDAKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISM-GYNMGE 760 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 + R + D + G V+F F + + Sbjct: 761 AEFA----RIMSIVDPNRMGVVTFQAFIDFMSR 789 >5Z1Q-A nrPDB Length = 95 Score = 48.2 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 28/85 (32%), Gaps = 4/85 (4%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIE 68 R S+ + F D NK G + +L+ +G P ++ Sbjct: 11 QPPKKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMN 70 Query: 69 SFFPDGSQRVDFPGFVRVLAHFRPV 93 + +G+ + F F+ ++ Sbjct: 71 EYDREGNGYIGFDDFLDIMTEKIKN 95 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 5/74 (6%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ ++ AF L+D ++ G I HE+ +R + E LE + E D +G+G Sbjct: 24 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILE-----LMNEYDREGNG 78 Query: 171 AVSFVEFTKSLEKM 184 + F +F + + Sbjct: 79 YIGFDDFLDIMTEK 92 Score = 27.8 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 8/96 (8%), Positives = 29/96 (30%), Gaps = 17/96 (17%) Query: 47 SRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKP 106 + ++Q + + F + + +D+ + + Sbjct: 13 PKKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAM-----------------RA 55 Query: 107 EPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 + ++ ++ YD + +G I + L ++ Sbjct: 56 LGFDVKKPEILELMNEYDREGNGYIGFDDFLDIMTE 91 >3TZ1-A nrPDB Length = 74 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 5/73 (6%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 +L AF++ D ++ G I + +L+ + G ++TE+++EN + E D DG G V Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSL-GDELTEDEIEN----MIAETDTDGSGTV 60 Query: 173 SFVEFTKSLEKMD 185 + EF + D Sbjct: 61 DYEEFKCLMMSSD 73 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLGDRI---IESFFPDGSQRVDFPGFVR 85 L FR LD+ KKG + L+ + +L D I I DGS VD+ F Sbjct: 8 ELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFKC 67 Query: 86 VL 87 ++ Sbjct: 68 LM 69 >1Y1X-A nrPDB Length = 191 Score = 47.0 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 60/156 (38%), Gaps = 32/156 (20%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG----DRIIESFFPDGSQRVDFPGFV 84 L FRA+D + G +S +L + A P ++++ + + S + F F Sbjct: 27 QELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEITFDEFK 86 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 L HF + F+ D DG++ +E+ L L Sbjct: 87 D-LHHFILS----------------------MREGFRKRDSSGDGRLDSNEVRAAL-LSS 122 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 G QV+E+ + + +++ D G++ F ++ + Sbjct: 123 GYQVSEQTFQAL----MRKFDRQRRGSLGFDDYVEL 154 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 37/122 (30%), Gaps = 28/122 (22%) Query: 55 GALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRN 114 + N + DGS + P L+ P L + Sbjct: 21 RHMNDNQELMEWFRAVDTDGSGAISVPELNAALS-------------SAGVPFSLATTEK 67 Query: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 LH +YD + G+I+ E + ++ ++ ++ D GDG + Sbjct: 68 LLH----MYDKNHSGEITFDEFKDLHHFILSMR-----------EGFRKRDSSGDGRLDS 112 Query: 175 VE 176 E Sbjct: 113 NE 114 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 33/91 (36%), Gaps = 6/91 (6%) Query: 87 LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV 146 +AH + +N + + + F+ D D G IS E+ L GV Sbjct: 1 MAHHHHHHMPTSTGVYAPSARHMNDNQELMEW-FRAVDTDGSGAISVPELNAALSS-AGV 58 Query: 147 QVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 + E + D++ G ++F EF Sbjct: 59 PFSLATTEKLLHMY----DKNHSGEITFDEF 85 Score = 32.8 bits (73), Expect = 0.096, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 20/66 (30%), Gaps = 4/66 (6%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDRIIESFFPDGSQRVDF 80 +L + FR D + G L + L G ++ F + F Sbjct: 89 HHFILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALMRKFDRQRRGSLGF 148 Query: 81 PGFVRV 86 +V + Sbjct: 149 DDYVEL 154 Score = 29.7 bits (65), Expect = 0.79, Method: Composition-based stats. Identities = 17/123 (13%), Positives = 32/123 (26%), Gaps = 21/123 (17%) Query: 27 SLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPG---- 82 SL D+N G ++ + + + G R+D Sbjct: 61 SLATTEKLLHMYDKNHSGEITFDEFKDLHH--FILSMREGFRKRDSSGDGRLDSNEVRAA 118 Query: 83 ------------FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 F ++ F D + R + F YD +R G+ Sbjct: 119 LLSSGYQVSEQTFQALMRKFDRQRRGSLGFDDYVELSIFVCR---VRNVFAFYDRERTGQ 175 Query: 131 ISR 133 ++ Sbjct: 176 VTF 178 >5XND-A nrPDB Length = 114 Score = 47.0 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 +++ AF + D D+ G I E+ L+ E ++ D DGD Sbjct: 43 GKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAE--TKAFLKAGDSDGD 100 Query: 170 GAVSFVEFTKSLE 182 G + EF ++ Sbjct: 101 GKIGIDEFAAMIK 113 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 7/76 (9%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESF----F 71 + G S S + F +D++K G++ +L+ Q L D ++F Sbjct: 37 KACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGD 96 Query: 72 PDGSQRVDFPGFVRVL 87 DG ++ F ++ Sbjct: 97 SDGDGKIGIDEFAAMI 112 >3MSE-B nrPDB Length = 180 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 60/160 (37%), Gaps = 27/160 (16%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLG-DRIIESFFPDGSQRVDFPGFVR 85 + ++ F LD N G LS ++ + ++ + +RI+++ + + + F+ Sbjct: 38 IKYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWDINRILQALDINDRGNITYTEFMA 97 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG 145 ++ +E L AF D D DG IS+ +++ ++ V Sbjct: 98 GCYRWKNIESTF------------------LKAAFNKIDKDEDGYISKSDIVSLVHDKVL 139 Query: 146 VQVTEE----QLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + + +I +E + +SF EF + Sbjct: 140 DNNDIDNFFLSVHSIKKGIPREHIIN---KISFQEFKDYM 176 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 30/73 (41%), Gaps = 7/73 (9%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 +N+ ++ F D + +G +S E+ VL + + +R +Q D + Sbjct: 34 INNHIKYINELFYKLDTNHNGSLSHREIYTVLASVGIKKWD-------INRILQALDIND 86 Query: 169 DGAVSFVEFTKSL 181 G +++ EF Sbjct: 87 RGNITYTEFMAGC 99 >3AKA-A nrPDB Length = 166 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 50/169 (29%), Gaps = 38/169 (22%) Query: 30 RLHHRFRALDRNKKGYLSRMDL--------------------QQIGALAVNPLGDRIIES 69 R+ RF D++ G++ R D Q + L + Sbjct: 5 RIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYG-GAEALWQGLAGI 63 Query: 70 FFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDG 129 DG QR+ FV + + LH A + D D DG Sbjct: 64 ADRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPF----------LHAALGVADTDGDG 113 Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 ++ + + L E++A + D DGDG V E Sbjct: 114 AVTVADTARALTAFG-------VPEDLARQAAAALDTDGDGKVGETEIV 155 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 46/131 (35%), Gaps = 12/131 (9%) Query: 67 IESFFPDGSQRVDFPGF----VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 +F DG+ +D F +LA F D E L + Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIA----- 64 Query: 123 YDLDRDGKISRHEMLQVLRLMVGVQVT--EEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 D D D +I+R E + + + E + AD DGDGAV+ + ++ Sbjct: 65 -DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARA 123 Query: 181 LEKMDVEQKMS 191 L V + ++ Sbjct: 124 LTAFGVPEDLA 134 Score = 34.7 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 26/76 (34%), Gaps = 10/76 (13%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV----------QVTEEQLENIADRTVQ 162 ++ F +D D +G I R + + ++ Q E + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 163 EADEDGDGAVSFVEFT 178 AD DGD ++ EF Sbjct: 63 IADRDGDQRITREEFV 78 Score = 27.8 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 4/72 (5%) Query: 26 ASLLR--LHHRFRALDRNKKGYLSR-MDLQQIGALAVN-PLGDRIIESFFPDGSQRVDFP 81 A + R LH D + G ++ + + A V L + + DG +V Sbjct: 93 AEIARPFLHAALGVADTDGDGAVTVADTARALTAFGVPEDLARQAAAALDTDGDGKVGET 152 Query: 82 GFVRVLAHFRPV 93 V A + V Sbjct: 153 EIVPAFARYFTV 164 >4NQG-A nrPDB Length = 197 Score = 46.3 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 33/191 (17%), Positives = 64/191 (33%), Gaps = 30/191 (15%) Query: 1 MGSRSSHAAVIPDGDSIRRETGFSQAS-LLRLHHRFRALDRNKKGYLSRMDLQQIGALAV 59 MGSR + ++ +T F + R H F LD N G ++ ++ + + Sbjct: 2 MGSRYA----------VKLDTDFDNPKWIARHKHMFNFLDINSNGQINLNEMVHKASNII 51 Query: 60 NPLGDRIIES--------FFPDGSQRVDFPG---FVRVLAHFRPVEDEDTETQDPKKPEP 108 E G +++ + + ++ + + E + Sbjct: 52 CKKLGATEEQTRRHQKCVEDFFGGAGLEYDKDTTWPEYIEGWKRLAKTELERHSKNRVTL 111 Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 + + L F + D D +G +S E +Q +Q + T D DG Sbjct: 112 IRLWGDAL---FDIIDKDGNGSVSLDEWIQYTHCAG-----IQQSRGQCEATFAHCDLDG 163 Query: 169 DGAVSFVEFTK 179 DG + E T+ Sbjct: 164 DGKLDVDEMTR 174 >3SIA-A nrPDB Length = 220 Score = 46.3 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 39/100 (39%), Gaps = 7/100 (7%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQ---IGALAVNP-LGDRIIESFFPDGSQRVDFP 81 R++ F +DR++ G L +L G + ++P R++ F D + + F Sbjct: 48 DQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALRMMRIFDTDFNGHISFY 107 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQ 121 F +A ++ +E + +++ A Q Sbjct: 108 EF---MAMYKFMELAYNLFVMNARARSGTLEPHEILPALQ 144 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQ 162 P + +++ F D DR G + +E++ + + G++++ + A R ++ Sbjct: 40 PLLNTIPLDQYTRIYQWFMGVDRDRSGTLEINELM-MGQFPGGIRLSPQT----ALRMMR 94 Query: 163 EADEDGDGAVSFVEFTKSLEKMDVEQKMSI 192 D D +G +SF EF + M++ + + Sbjct: 95 IFDTDFNGHISFYEFMAMYKFMELAYNLFV 124 >2JOJ-A nrPDB Length = 77 Score = 46.3 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 28/77 (36%), Gaps = 4/77 (5%) Query: 23 FSQASLLRLHHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRV 78 S+ + F D NK G + +L+ +G P ++ + +G+ + Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYI 60 Query: 79 DFPGFVRVLAHFRPVED 95 F F+ ++ D Sbjct: 61 GFDDFLDIMTEKIKNRD 77 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 5/74 (6%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ ++ AF L+D ++ G I HE+ +R + E LE + E D +G+G Sbjct: 4 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILE-----LMNEYDREGNG 58 Query: 171 AVSFVEFTKSLEKM 184 + F +F + + Sbjct: 59 YIGFDDFLDIMTEK 72 Score = 26.6 bits (57), Expect = 7.4, Method: Composition-based stats. Identities = 7/78 (8%), Positives = 24/78 (30%), Gaps = 17/78 (21%) Query: 65 RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYD 124 + F + + +D+ + + + ++ ++ YD Sbjct: 11 EAFDLFDTNKTGSIDYHELKVAM-----------------RALGFDVKKPEILELMNEYD 53 Query: 125 LDRDGKISRHEMLQVLRL 142 + +G I + L ++ Sbjct: 54 REGNGYIGFDDFLDIMTE 71 >2N8Y-A nrPDB Length = 153 Score = 46.3 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 19/127 (14%), Positives = 43/127 (33%), Gaps = 26/127 (20%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQI-----GALAVNPLGD----RIIESFF 71 + SQ + F DR+ G L + + + +P G+ RI+ Sbjct: 2 SSISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVD 61 Query: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 P+ V F F+ ++ +++ +F++ D++ I Sbjct: 62 PNRLGVVTFQAFIDFMSR----------------ETADTDTADQVMASFKILAGDKN-YI 104 Query: 132 SRHEMLQ 138 + E+ + Sbjct: 105 TMDELRR 111 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 N+ +F +D D G + E L + + Q E R + D + G V+ Sbjct: 10 NEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVT 69 Query: 174 FVEFTKSLEK 183 F F + + Sbjct: 70 FQAFIDFMSR 79 >4D1E-A nrPDB Length = 876 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 40/125 (32%), Gaps = 21/125 (16%) Query: 18 RRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNP---LGDRIIESFFPD 73 R G +Q + F DR K G + D + + ++ + RI+ P+ Sbjct: 727 RDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPN 786 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 G V F F+ + ++ +F++ D+ I Sbjct: 787 GQGTVTFQSFIDFMTR----------------ETADTDTAEQVIASFRILASDKP-YILA 829 Query: 134 HEMLQ 138 E+ + Sbjct: 830 EELRR 834 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 36/93 (38%), Gaps = 5/93 (5%) Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 R + + +T+ + N+ +F +D ++G + + L M G + E Sbjct: 715 RTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISM-GYDLGE 773 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 + R + D +G G V+F F + + Sbjct: 774 AEFA----RIMTLVDPNGQGTVTFQSFIDFMTR 802 >2KYF-A nrPDB Length = 108 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 34/99 (34%), Gaps = 2/99 (2%) Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM 143 + D + + + ++L F++ D D+ G I E+ L+ Sbjct: 11 IAAALRDCQAPDSFSPKKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRF 70 Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 E + AD DGDG + EF + ++ Sbjct: 71 ESGARVLTASE--TKTFLAAADHDGDGKIGAEEFQEMVQ 107 Score = 35.1 bits (79), Expect = 0.022, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 31/75 (41%), Gaps = 11/75 (14%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRI---------IESFF 71 +G S+ S +L FR LD ++ G++ +L+ L G R+ + + Sbjct: 33 SGMSKKSSSQLKEIFRILDNDQSGFIEEDELK--YFLQRFESGARVLTASETKTFLAAAD 90 Query: 72 PDGSQRVDFPGFVRV 86 DG ++ F + Sbjct: 91 HDGDGKIGAEEFQEM 105 >5ZGM-A nrPDB Length = 110 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 27/75 (36%), Gaps = 2/75 (2%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 ++ F++ D D+ G I E+ VL+ E + D D Sbjct: 37 KGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTE--TKALLAAGDSDH 94 Query: 169 DGAVSFVEFTKSLEK 183 DG + EF K + + Sbjct: 95 DGKIGADEFAKMVAQ 109 Score = 30.1 bits (66), Expect = 0.57, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 28/68 (41%), Gaps = 7/68 (10%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI-------GALAVNPLGDRIIESFFPDGSQRVDFP 81 ++ F LD+++ G++ +L+ + G + ++ + D ++ Sbjct: 42 AQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAGDSDHDGKIGAD 101 Query: 82 GFVRVLAH 89 F +++A Sbjct: 102 EFAKMVAQ 109 >1ZFS-A nrPDB Length = 93 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 32/57 (56%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 K+S+ E+ +L+ + + ++ + D+ ++E DE+GDG V F EF + + V Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTV 83 Score = 28.1 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 9/25 (36%), Positives = 15/25 (60%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLA 88 D+I++ +G VDF FV ++A Sbjct: 55 DKIMKELDENGDGEVDFQEFVVLVA 79 >2VRG-A nrPDB Length = 124 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 7/90 (7%) Query: 100 TQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQ 152 KPE S + + F+++D D + + E+ + + + ++E++ Sbjct: 35 EGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDE 94 Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLE 182 L NI D +++ D++ DG + + EF KSL+ Sbjct: 95 LINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 124 >3LCP-C nrPDB Length = 93 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 44/87 (50%), Gaps = 7/87 (8%) Query: 103 PKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLEN 155 KPE S + + F+++D D + + E+ + + + ++E++L N Sbjct: 7 INKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELIN 66 Query: 156 IADRTVQEADEDGDGAVSFVEFTKSLE 182 I D +++ D++ DG + + EF KSL+ Sbjct: 67 IIDGVLRDDDKNNDGYIDYAEFAKSLQ 93 >1UHK-A nrPDB Length = 191 Score = 44.7 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 63/165 (38%), Gaps = 23/165 (13%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQ------QIGALAVNPLGDR----IIESFFPDGSQR 77 + R H F LD N G +S ++ I L P + +E+FF G Sbjct: 15 IGRHKHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFF--GGAG 72 Query: 78 VDF---PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRH 134 + + + + ++ + ++ E +P + + L F + D D++G I+ Sbjct: 73 MKYGVETDWPAYIEGWKKLATDELEKYAKNEPTLIRIWGDAL---FDIVDKDQNGAITLD 129 Query: 135 EMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 E + +Q +E+ + T + D D G + E T+ Sbjct: 130 EWKAYTKAAGIIQSSED-----CEETFRVCDIDESGQLDVDEMTR 169 >3A4U-B nrPDB Length = 143 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 7/90 (7%) Query: 100 TQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQ 152 KPE S + + F+++D D + + E+ + + + ++E++ Sbjct: 54 EGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDE 113 Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLE 182 L NI D +++ D++ DG + + EF KSL+ Sbjct: 114 LINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 143 >5PAL-A nrPDB Length = 109 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 27/75 (36%), Gaps = 2/75 (2%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 ++ F++ D D+ G I E+ VL+ E + D D Sbjct: 36 KGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTE--TKALLAAGDSDH 93 Query: 169 DGAVSFVEFTKSLEK 183 DG + EF K + + Sbjct: 94 DGKIGADEFAKMVAQ 108 Score = 30.8 bits (68), Expect = 0.39, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 29/68 (42%), Gaps = 7/68 (10%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI------GALAVNPLGDR-IIESFFPDGSQRVDFP 81 ++ F LD+++ G++ +L+ + +N + ++ + D ++ Sbjct: 41 AQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGAD 100 Query: 82 GFVRVLAH 89 F +++A Sbjct: 101 EFAKMVAQ 108 >1SL8-A nrPDB Length = 191 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 62/165 (37%), Gaps = 23/165 (13%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQ------QIGALAVNPLGDR----IIESFFPDGSQR 77 + R H F LD N G +S ++ I L P + +E+FF G Sbjct: 15 IGRHKHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFF--GGAG 72 Query: 78 VDF---PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRH 134 + + + + ++ + E+ + + + + L F + D D++G IS Sbjct: 73 MKYGVETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDAL---FDIIDKDQNGAISLD 129 Query: 135 EMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 E + +Q +E+ + T + D D G + E T+ Sbjct: 130 EWKAYTKSAGIIQSSED-----CEETFRVCDIDESGQLDVDEMTR 169 >5I2L-A nrPDB Length = 120 Score = 43.6 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 5/70 (7%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 + F+ YD RDG I E+ ++ ++ Q ++E DED D +S Sbjct: 31 KDMEKMFKQYDAGRDGFIDLMELKLMM-----EKLGAPQTHLGLKNMIKEVDEDFDSKLS 85 Query: 174 FVEFTKSLEK 183 F EF K Sbjct: 86 FREFLLIFRK 95 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG----DRIIESFFPDGSQR 77 FS+ + + F+ D + G++ M+L+ + P +I+ D + Sbjct: 24 EFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSK 83 Query: 78 VDFPGFVRVL 87 + F F+ + Sbjct: 84 LSFREFLLIF 93 >5ZH6-A nrPDB Length = 107 Score = 43.2 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 26/67 (38%), Gaps = 2/67 (2%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 L F + D DR G I E+ L+ ++ E + + D D DG + Sbjct: 42 LAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETE--TNAFLAAGDSDHDGKIGVD 99 Query: 176 EFTKSLE 182 EF ++ Sbjct: 100 EFKAMVK 106 Score = 33.2 bits (74), Expect = 0.083, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 28/73 (38%), Gaps = 7/73 (9%) Query: 21 TGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESF----FPD 73 +G + S L F LD+++ G++ +L+ Q + L + +F D Sbjct: 32 SGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSD 91 Query: 74 GSQRVDFPGFVRV 86 ++ F + Sbjct: 92 HDGKIGVDEFKAM 104 Score = 26.2 bits (56), Expect = 9.5, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 24/79 (30%), Gaps = 14/79 (17%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 ++ + D S ++ L +F E ET+ Sbjct: 43 AKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAG-------------- 88 Query: 124 DLDRDGKISRHEMLQVLRL 142 D D DGKI E +++ Sbjct: 89 DSDHDGKIGVDEFKAMVKA 107 >3PAT-A nrPDB Length = 110 Score = 42.8 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 2/66 (3%) Query: 112 RRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGA 171 N + F+ D D G I E+ VL+ E ++ AD+DGDG Sbjct: 40 SANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAE--TKAFLKAADKDGDGK 97 Query: 172 VSFVEF 177 + EF Sbjct: 98 IGIDEF 103 Score = 27.8 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 32 HHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDR---IIESFFPDGSQRVDFPGF 83 F+A+D + G++ + L+ A + +++ DG ++ F Sbjct: 45 KKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEF 103 >1S6J-A nrPDB Length = 87 Score = 42.8 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 5/63 (7%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 L F++ D D G I+ E+ L+ VG ++ E +++++ D AD D G + + Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLKR-VGSELMESEIKDLMDA----ADIDKSGTIDYG 79 Query: 176 EFT 178 EF Sbjct: 80 EFI 82 Score = 40.1 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ-IGALAVNPLGDRIIESFFP---DGSQR 77 S+ + L F+ +D + G ++ +L+ + + + I + D S Sbjct: 16 RLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGT 75 Query: 78 VDFPGFVRVLAH 89 +D+ F+ H Sbjct: 76 IDYGEFIAATVH 87 Score = 26.6 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + +++EE++ + + D D G ++F E L+++ Sbjct: 13 MAERLSEEEIGGL-KELFKMIDTDNSGTITFDELKDGLKRV 52 >4OCI-A nrPDB Length = 146 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 49/152 (32%), Gaps = 23/152 (15%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPDGSQR-VDFPGFVRV 86 L F D + GYL+ + + + L V I ++ + R + + F Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRGMSYELFTSC 65 Query: 87 LAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV 146 + + ++++ A + D D+ G I E+ ++L + Sbjct: 66 FSQLKTKSFN----------------KDEIKTAINVLDKDKKGFIPAIELRRILSTIGDN 109 Query: 147 QVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 + + I D D G V +F Sbjct: 110 M----EQKEITD-LFTFMGIDEQGVVKVDDFI 136 Score = 30.5 bits (67), Expect = 0.48, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVT 149 + L +F L+D D DG ++ +E ++R++ V T Sbjct: 1 MQKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMET 41 >2L0P-A nrPDB Length = 94 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 33/57 (57%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 K+S+ E+ ++L+ + + ++ + D+ ++E DE+GDG V F E+ + + V Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTV 84 Score = 26.6 bits (57), Expect = 7.8, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 15/25 (60%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLA 88 D++++ +G VDF +V ++A Sbjct: 56 DKVMKELDENGDGEVDFQEYVVLVA 80 >5E1J-A nrPDB Length = 741 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 43/104 (41%), Gaps = 6/104 (5%) Query: 93 VEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQ 152 V D E + +R L AF L D D++G+I +++ +++ + + + Sbjct: 304 VYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKI 363 Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 + E D+ D ++ EF D+ Q +++R K Sbjct: 364 SKEEFGLIFDELDDTRDFKINKDEF------ADLCQAIALRFQK 401 Score = 35.5 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 11/82 (13%), Positives = 28/82 (34%), Gaps = 10/82 (12%) Query: 15 DSIRRE-TGFSQASLLRLHHRFRALDRNKKGYLSRMD----LQQIGALAVNPLGDR---- 65 + + ++ +G Q L F +D +K G + + +Q+ P + Sbjct: 310 EQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFG 369 Query: 66 -IIESFFPDGSQRVDFPGFVRV 86 I + +++ F + Sbjct: 370 LIFDELDDTRDFKINKDEFADL 391 >5XOP-A nrPDB Length = 66 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+ D++ DG +S E+ + ++ E + + D+DGDG + F EF K Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKN-----EQLLQLIFKSIDKDGDGFIDFEEFAK 60 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 32 HHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 F+ +D N G +S +++ + A+ L I +S DG +DF F + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKFY 62 Query: 88 A 88 Sbjct: 63 G 63 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 22/73 (30%), Gaps = 17/73 (23%) Query: 63 GDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 + + + +G V + ++ R +++ L F+ Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN-----------------EQLLQLIFKS 44 Query: 123 YDLDRDGKISRHE 135 D D DG I E Sbjct: 45 IDKDGDGFIDFEE 57 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 10/21 (47%), Positives = 15/21 (71%) Query: 156 IADRTVQEADEDGDGAVSFVE 176 +A+ +E D +GDGAVS+ E Sbjct: 1 MAEALFKEIDVNGDGAVSYEE 21 Score = 27.4 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 4/28 (14%), Positives = 13/28 (46%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGA 56 L F+++D++ G++ + + Sbjct: 36 QLLQLIFKSIDKDGDGFIDFEEFAKFYG 63 >2LVV-A nrPDB Length = 226 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 52/158 (32%), Gaps = 15/158 (9%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL--QQIGALAVNPLGDRIIESFFPDGSQRVDFP 81 S R F+ D N G L ++ G L ++ + + + D Sbjct: 46 DAESKSRRIELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLG 105 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLR 141 V+ + E++ E + + +L F D D + E + L Sbjct: 106 NKVKGVG-----EEDLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEFKEALP 160 Query: 142 LMV--GVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 + GV +T+ E D +G G V+F EF Sbjct: 161 KLKEWGVDITDAT------TVFNEIDTNGSGVVTFDEF 192 Score = 32.4 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 26/80 (32%), Gaps = 5/80 (6%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQ----IGALAVNPLGDR-IIESFFPDGSQRVDFPG 82 + L F +D++ L + ++ + V+ + +GS V F Sbjct: 132 IFELTVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTFDE 191 Query: 83 FVRVLAHFRPVEDEDTETQD 102 F + D + ++ Sbjct: 192 FSCWAVTKKLQVCGDPDGEE 211 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 5/65 (7%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA-----DEDGDGAVSF 174 F+ +D + GK+ E+L ++ + L +I R +A G G Sbjct: 57 FKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEEDL 116 Query: 175 VEFTK 179 VEF + Sbjct: 117 VEFLE 121 >4YGB-B nrPDB Length = 104 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Query: 119 AFQLYDLDRDGKISRHEMLQVLRLMVGVQ-------VTEEQLENIADRTVQEADEDGDGA 171 F+++D D + + E+ + + + ++E++L NI D +++ D++ DG Sbjct: 34 YFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGY 93 Query: 172 VSFVEFTKSLE 182 + + EF KSL+ Sbjct: 94 IDYAEFAKSLQ 104 >2M1U-A nrPDB Length = 93 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 ++ + +L AF +D D DG +S E ++R G+ +TE ++ + AD + Sbjct: 21 MSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD--GLPMTEAEITE----FFEAADPNN 74 Query: 169 DGAVSFVEFTKSLEKMDVE 187 G + + F L +D Sbjct: 75 TGFIDYKAFAAMLYSVDES 93 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 25/65 (38%), Gaps = 3/65 (4%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRI---IESFFPDGSQRVDFPG 82 +L F D + G++S + + I + I E+ P+ + +D+ Sbjct: 23 DEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPMTEAEITEFFEAADPNNTGFIDYKA 82 Query: 83 FVRVL 87 F +L Sbjct: 83 FAAML 87 >1A75-A nrPDB Length = 108 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 110 NSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGD 169 + + AF D D+ G I E+ L++ E ++ D DGD Sbjct: 37 GKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAE--TKAFLKAGDSDGD 94 Query: 170 GAVSFVEFTKSLE 182 GA+ E+ ++ Sbjct: 95 GAIGVEEWVALVK 107 Score = 33.9 bits (76), Expect = 0.049, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 30/75 (40%), Gaps = 7/75 (9%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESF----F 71 + G S S + F +D++K G++ +L+ Q+ L D ++F Sbjct: 31 AKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGD 90 Query: 72 PDGSQRVDFPGFVRV 86 DG + +V + Sbjct: 91 SDGDGAIGVEEWVAL 105 >1QXP-A nrPDB Length = 900 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 28/188 (14%), Positives = 57/188 (30%), Gaps = 43/188 (22%) Query: 17 IRRETGFSQASLLR-LHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD----------- 64 + E S+ + F L + +S +LQ I ++ D Sbjct: 521 LPDEKVLSEEEIDDNFKTLFSKLAGD-DMEISVKELQTILNRIISKHKDLRTNGFSLESC 579 Query: 65 -RIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 ++ DG+ ++ F + R F+ + Sbjct: 580 RSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTI-----------------------FRKF 616 Query: 124 DLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 DLD+ G +S +EM + QL + D + + F F + L + Sbjct: 617 DLDKSGSMSAYEMRMAIEAAGFKLPC--QLHQVIVARFA----DDELIIDFDNFVRCLVR 670 Query: 184 MDVEQKMS 191 +++ K+ Sbjct: 671 LEILFKIF 678 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 32/107 (29%), Gaps = 26/107 (24%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF---FPDGSQRVDFPGFV 84 + + ++ + ++ G + +L A L I + D + +DF F+ Sbjct: 803 IKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFI 862 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 L + AF+ D + G+I Sbjct: 863 SCLVRLDAMFR-----------------------AFRSLDKNGTGQI 886 Score = 34.7 bits (78), Expect = 0.029, Method: Composition-based stats. Identities = 20/138 (14%), Positives = 45/138 (32%), Gaps = 8/138 (5%) Query: 65 RIIESFFPDGSQRV--DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQ- 121 +I + P+ + + D ++ + + + + ++ F+ Sbjct: 676 KIFKQLDPENTGTIQLDLISWLSFSVLGKLAAAIEHHHHHHMHYSNIEANESEEERQFRK 735 Query: 122 LYDL--DRDGKISRHEMLQVLRLMVGVQVTEEQLENIADR---TVQEADEDGDGAVSFVE 176 L+ D ++S E++ +L +V + D V D D G + F E Sbjct: 736 LFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEE 795 Query: 177 FTKSLEKMDVEQKMSIRI 194 F + Q + R Sbjct: 796 FKYLWNNIKKWQGIYKRF 813 Score = 30.1 bits (66), Expect = 0.71, Method: Composition-based stats. Identities = 26/193 (13%), Positives = 56/193 (29%), Gaps = 62/193 (32%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQI--------GALAVNPLG----DRIIESFFPD 73 + F L + +S +L I L + G ++ D Sbjct: 728 EEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 786 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 + ++ F F + L + K ++ ++ DR G I Sbjct: 787 TTGKLGFEEF-----------------------KYLWNNIKKWQGIYKRFETDRSGTIGS 823 Query: 134 HE-----------MLQVLRLMVGVQVTEEQLENIAD-------------RTVQEADEDGD 169 +E + Q + M+ + ++E D R + D++G Sbjct: 824 NELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGT 883 Query: 170 GAV--SFVEFTKS 180 G + + E+ + Sbjct: 884 GQIQVNIQEWLQL 896 >1NYA-A nrPDB Length = 176 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 56/171 (32%), Gaps = 33/171 (19%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQ------RVDFPGF 83 RL RF D + G L R D ++ I E+F D + F G Sbjct: 8 RLKKRFDRWDFDGNGALERADFEK--------EAQHIAEAFGKDAGAAEVQTLKNAFGGL 59 Query: 84 VRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQ------------LYDLDRDGKI 131 LA V + + T++ N + +F + D + DG+I Sbjct: 60 FDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQI 119 Query: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 + E L + + + + D +G+G +S E ++ Sbjct: 120 NADEFAAWLTALGMSKAEAAE-------AFNQVDTNGNGELSLDELLTAVR 163 Score = 33.2 bits (74), Expect = 0.073, Method: Composition-based stats. Identities = 20/148 (13%), Positives = 41/148 (27%), Gaps = 39/148 (26%) Query: 26 ASLLRLHHRFR-ALD-------RNKKGYLSRMDLQQIGALAVNPLGDRIIESF------- 70 A + L + F D G L+ ++ + G+ Sbjct: 47 AEVQTLKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKG 106 Query: 71 -----FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDL 125 + +++ F L L + + AF D Sbjct: 107 IVGMCDKNADGQINADEFAAWLT-------------------ALGMSKAEAAEAFNQVDT 147 Query: 126 DRDGKISRHEMLQVLRLMVGVQVTEEQL 153 + +G++S E+L +R ++ E L Sbjct: 148 NGNGELSLDELLTAVRDFHFGRLDVELL 175 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 35/86 (40%), Gaps = 10/86 (11%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEM---LQVLRLMVGVQVTEEQLEN-------IADRTVQ 162 ++L F +D D +G + R + Q + G +++ + D + Sbjct: 6 SDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAK 65 Query: 163 EADEDGDGAVSFVEFTKSLEKMDVEQ 188 EA DG+++ +F + E + EQ Sbjct: 66 EAGVGSDGSLTEEQFIRVTENLIFEQ 91 >2L50-A nrPDB Length = 102 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 26/48 (54%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 KIS+ ++L+ + +++ AD+ +Q D + DG +SF E+ Sbjct: 31 KISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEY 78 >2KQY-A nrPDB Length = 108 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 +++ F + D D+ G I E+ L+ E + D DGDG + Sbjct: 41 DQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAE--TKAFLAAGDTDGDGKIG 98 Query: 174 FVEFTKSLE 182 EF ++ Sbjct: 99 VEEFQSLVK 107 Score = 32.0 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 27/71 (38%), Gaps = 11/71 (15%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF---------FP 72 G S + ++ F LD++K G++ +LQ L R++ S Sbjct: 34 GLSSKTPDQIKKVFGILDQDKSGFIEEEELQ--LFLKNFSSSARVLTSAETKAFLAAGDT 91 Query: 73 DGSQRVDFPGF 83 DG ++ F Sbjct: 92 DGDGKIGVEEF 102 >5CPV-A nrPDB Length = 109 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 2/88 (2%) Query: 95 DEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLE 154 D K + + + AF + D D+ G I E+ L+ E Sbjct: 23 DSFNHKAFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGE 82 Query: 155 NIADRTVQEADEDGDGAVSFVEFTKSLE 182 ++ D DGDG + EFT ++ Sbjct: 83 --TKTFLKAGDSDGDGKIGVDEFTALVK 108 Score = 29.7 bits (65), Expect = 0.80, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 7/75 (9%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESF----F 71 + G + S + F +D++K G++ +L+ Q L D ++F Sbjct: 32 AKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGD 91 Query: 72 PDGSQRVDFPGFVRV 86 DG ++ F + Sbjct: 92 SDGDGKIGVDEFTAL 106 >4P5X-A nrPDB Length = 315 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 45/125 (36%), Gaps = 16/125 (12%) Query: 34 RFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRV-LAHFRP 92 F+ D++ G ++ ++++I G II P F+R+ H R Sbjct: 98 AFQLFDKSGNGEVTFENVKEI-------FGQTIIHHHIPFNWDC----EFIRLHFGHNRK 146 Query: 93 VEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQ 152 TE + L R AF L D + G IS + ++ + +T Sbjct: 147 KHLNYTEFTQFLQELQLEHARQ----AFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFV 202 Query: 153 LENIA 157 EN+ Sbjct: 203 EENLV 207 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 21/168 (12%), Positives = 56/168 (33%), Gaps = 32/168 (19%) Query: 30 RLHHRFRAL---DRNKKGYLSRMDLQQIG-ALAVNPLGDRIIESF-----FPDGSQRVDF 80 L + F + + + Y++ D Q L +P + I + + Sbjct: 19 ELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISY 78 Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 F+ + P+ + AFQL+D +G+++ + ++ Sbjct: 79 QEFLAFESVL-------------CAPDSMFIV------AFQLFDKSGNGEVTFENVKEIF 119 Query: 141 -RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVE 187 + ++ + + +++ EFT+ L+++ +E Sbjct: 120 GQTIIHHHIPFNWDCEFIRLHFG---HNRKKHLNYTEFTQFLQELQLE 164 >2PMY-A nrPDB Length = 91 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 24/66 (36%), Gaps = 2/66 (3%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDR-IIESFFPDGSQRVDFP 81 L RL F A D N+ G L R + + + L V P + + D + F Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITFQ 81 Query: 82 GFVRVL 87 F R Sbjct: 82 EFARGF 87 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 7/81 (8%) Query: 99 ETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIAD 158 E + + +L F D +R G++ R E + + E + Sbjct: 12 ENLYFQGADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAV----- 66 Query: 159 RTVQEADEDGDGAVSFVEFTK 179 Q D D DGA++F EF + Sbjct: 67 --FQRLDADRDGAITFQEFAR 85 >1RTP-1 nrPDB Length = 109 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 31/93 (33%), Gaps = 2/93 (2%) Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 D + + + + F + D D+ G I E+ +L+ Sbjct: 18 FTAADSFDHKKFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDL 77 Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 E + D+DGDG + EF+ + + Sbjct: 78 SAKE--TKTLMAAGDKDGDGKIGVEEFSTLVAE 108 Score = 30.1 bits (66), Expect = 0.57, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 7/75 (9%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD-------RIIESFFPDG 74 G + S + F LD++K G++ +L I + D ++ + DG Sbjct: 34 GLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDG 93 Query: 75 SQRVDFPGFVRVLAH 89 ++ F ++A Sbjct: 94 DGKIGVEEFSTLVAE 108 >5VE9-A nrPDB Length = 91 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 5/73 (6%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG 168 +N +++++ F+ D D+DGKI+R E + ++ + +LE A + D DG Sbjct: 22 MNHKKSRVMDFFRRIDKDQDGKITRQEFID---GILASKFPTTKLEMTAVADI--FDRDG 76 Query: 169 DGAVSFVEFTKSL 181 DG + + EF +L Sbjct: 77 DGYIDYYEFVAAL 89 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 35 FRALDRNKKGYLSRMDLQQIGALAVNPL----GDRIIESFFPDGSQRVDFPGFVRVL 87 FR +D+++ G ++R + + P + + F DG +D+ FV L Sbjct: 33 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAAL 89 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 11/88 (12%), Positives = 24/88 (27%), Gaps = 18/88 (20%) Query: 48 RMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPE 107 R + + + D D ++ F+ D Sbjct: 15 RKKYMRWMNHKKSRVMD-FFRRIDKDQDGKITRQEFI-----------------DGILAS 56 Query: 108 PLNSRRNKLHYAFQLYDLDRDGKISRHE 135 + + ++ ++D D DG I +E Sbjct: 57 KFPTTKLEMTAVADIFDRDGDGYIDYYE 84 >1IJ5-A nrPDB Length = 323 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 53/154 (34%), Gaps = 30/154 (19%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQ---IGALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 L L FR +D N G LSR + ++ + D + D S V F +V Sbjct: 187 LAALVADFRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQDALFRYADEDESDDVGFSEYV 246 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMV 144 + + ++ YAF D D+ G++S+ E+ +VL Sbjct: 247 HLGLCLLVL---------------------RILYAFA--DFDKSGQLSKEEVQKVLEDAH 283 Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 E + D D ++S+ EF Sbjct: 284 ----IPESARKKFEHQFSVVDVDDSKSLSYQEFV 313 Score = 30.5 bits (67), Expect = 0.54, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 51/159 (32%), Gaps = 25/159 (15%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVD 79 + S+ L F + + G S DL+Q+ + + + Sbjct: 113 KPMLSEEDTNILRQLFLSSAVSGSGKFSFQDLKQV-----------LAKYADTIPEGPLK 161 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F VE++ + + L F+ D + +G +SR E + Sbjct: 162 --------KLFVMVENDTKGRMSYITLVAVANDLAALVADFRKIDTNSNGTLSRKEFREH 213 Query: 140 LRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 + + +++ D + ADED V F E+ Sbjct: 214 FVRLGFDK------KSVQDALFRYADEDESDDVGFSEYV 246 >1TIZ-A nrPDB Length = 67 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+ +D ++DGK+S E +V + + + +E D DG+G ++ EFT Sbjct: 7 FEKFDKNKDGKLSLDEFREVALAF-----SPYFTQEDIVKFFEEIDVDGNGELNADEFTS 61 Query: 180 SLEKM 184 +EKM Sbjct: 62 CIEKM 66 Score = 32.8 bits (73), Expect = 0.097, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 19/56 (33%), Gaps = 4/56 (7%) Query: 32 HHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR----IIESFFPDGSQRVDFPGF 83 F D+NK G LS + +++ E DG+ ++ F Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEF 59 Score = 26.6 bits (57), Expect = 7.6, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 14/24 (58%) Query: 157 ADRTVQEADEDGDGAVSFVEFTKS 180 A R ++ D++ DG +S EF + Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREV 26 >1JUO-A nrPDB Length = 198 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 45/151 (29%), Gaps = 39/151 (25%) Query: 43 KGYLSRMDLQQIGAL-----AVNPLGDRIIESF----FPDGSQRVDFPGFVRVLAHFRPV 93 G + +LQ+ P D S + F F + A Sbjct: 46 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 105 Query: 94 EDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL 153 F +D DR G + E+ + L M G +++ + + Sbjct: 106 RQH-----------------------FISFDTDRSGTVDPQELQKALTTM-GFRLSPQAV 141 Query: 154 ENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +IA R +G ++F ++ K+ Sbjct: 142 NSIAKR------YSTNGKITFDDYIACCVKL 166 Score = 31.6 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 24/69 (34%), Gaps = 4/69 (5%) Query: 31 LHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 F + D ++ G + +LQ ++P I + + ++ F ++ Sbjct: 105 WRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYST-NGKITFDDYIACC 163 Query: 88 AHFRPVEDE 96 R + D Sbjct: 164 VKLRALTDS 172 Score = 31.6 bits (70), Expect = 0.25, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 13/85 (15%) Query: 13 DGDSIRRETGFSQASLLRLHHRFR---------ALDRNKKGYLSRMDLQQIGALAVNPLG 63 D D ++R +Q+ + + F LDR+ G + + +++ A+ +N Sbjct: 50 DADELQR--CLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAV-LNGWR 106 Query: 64 DRIIESFFPDGSQRVDFPGFVRVLA 88 I F D S VD + L Sbjct: 107 QHFIS-FDTDRSGTVDPQELQKALT 130 >4PAL-A nrPDB Length = 108 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 32/88 (36%), Gaps = 2/88 (2%) Query: 95 DEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLE 154 D + K + + + AF + D D+ G I E+ L+ E Sbjct: 22 DSFKHKEFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAE 81 Query: 155 NIADRTVQEADEDGDGAVSFVEFTKSLE 182 + + D+DGDG + EF ++ Sbjct: 82 --TKAFLADGDKDGDGMIGVDEFAAMIK 107 Score = 31.6 bits (70), Expect = 0.19, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF-------- 70 + G + SL + F +D++K G++ +L+ + +P + ++ Sbjct: 31 AKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELK-LFLQNFSPSARALTDAETKAFLADG 89 Query: 71 FPDGSQRVDFPGFVRVL 87 DG + F ++ Sbjct: 90 DKDGDGMIGVDEFAAMI 106 >2WCE-A nrPDB Length = 95 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 23/51 (45%) Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 +S+ E+ Q+L + + + + + D Q D + D V F EF + Sbjct: 31 LSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMV 81 Score = 30.8 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 35 FRALDRNKKGYLSRMDL-QQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLA 88 F L + + L +L I + + D I + + ++VDF F+ ++A Sbjct: 28 FDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVA 82 >1BU3-A nrPDB Length = 109 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 + + AF + D D+ G I E+ L++ E ++ D DGDG Sbjct: 39 KSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAE--TKAFLKAGDSDGDG 96 Query: 171 AVSFVEFTKSLE 182 A+ E+ ++ Sbjct: 97 AIGVDEWAALVK 108 Score = 34.3 bits (77), Expect = 0.039, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 30/75 (40%), Gaps = 7/75 (9%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESF----F 71 + G + S + F +D++K G++ +L+ Q+ + L D ++F Sbjct: 32 AKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGD 91 Query: 72 PDGSQRVDFPGFVRV 86 DG + + + Sbjct: 92 SDGDGAIGVDEWAAL 106 >1G33-A nrPDB Length = 73 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 + + F + D D+ G I E+ +L+ E + D+DGDG Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKE--TKTLMAAGDKDGDG 59 Query: 171 AVSFVEFTKSLEK 183 + EF+ + + Sbjct: 60 KIGVEEFSTLVAE 72 Score = 27.8 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 25/65 (38%), Gaps = 7/65 (10%) Query: 32 HHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD-------RIIESFFPDGSQRVDFPGFV 84 F LD++K G++ +L I + D ++ + DG ++ F Sbjct: 8 KKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFS 67 Query: 85 RVLAH 89 ++A Sbjct: 68 TLVAE 72 >2NCO-A nrPDB Length = 102 Score = 40.1 bits (92), Expect = 7e-04, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 4/99 (4%) Query: 100 TQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGV--QVTEEQLENIA 157 + PK + ++ + F+ YD D G++ E+ +L+ + Sbjct: 1 SSKPKYNPEVEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDV 60 Query: 158 DRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 +Q AD + DG+VS E+ + K QK IR+ K Sbjct: 61 KIWLQMADTNSDGSVSLEEYEDLIIKSL--QKAGIRVEK 97 Score = 26.6 bits (57), Expect = 7.7, Method: Composition-based stats. Identities = 9/70 (12%), Positives = 23/70 (32%), Gaps = 11/70 (15%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDL--------QQIGALAVNPLGDRI---IESFFPD 73 +A L F+ D++ G L ++ ++G P + + ++ + Sbjct: 11 EAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTN 70 Query: 74 GSQRVDFPGF 83 V + Sbjct: 71 SDGSVSLEEY 80 >1RK9-A nrPDB Length = 110 Score = 39.7 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA-DEDGD 169 + + F + D D+ G I E+ +L+ G L + + A D+DGD Sbjct: 39 KSADDVKKVFHMLDKDKSGFIEEDELGFILK---GFSPDARDLSAKETKMLMAAGDKDGD 95 Query: 170 GAVSFVEFTKSLEK 183 G + EF+ + + Sbjct: 96 GKIGVDEFSTLVAE 109 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 28/75 (37%), Gaps = 7/75 (9%) Query: 22 GFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR-------IIESFFPDG 74 G + S + F LD++K G++ +L I D ++ + DG Sbjct: 35 GLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDG 94 Query: 75 SQRVDFPGFVRVLAH 89 ++ F ++A Sbjct: 95 DGKIGVDEFSTLVAE 109 >2SAS-A nrPDB Length = 185 Score = 39.7 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 38/94 (40%), Gaps = 11/94 (11%) Query: 112 RRNKLHYAFQLY-DLDRDGKI---SRHEMLQVLRLMVGVQVTEEQLENIADRTVQE---- 163 ++ K+ + F + D++ DG I +M+ + + +++ +++ E Sbjct: 6 QKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDL 65 Query: 164 ---ADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 AD + D VS+ E+ EK K + Sbjct: 66 KGRADINKDDVVSWEEYLAMWEKTIATCKSVADL 99 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 19/122 (15%), Positives = 40/122 (32%), Gaps = 6/122 (4%) Query: 70 FFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDG 129 + + F ++ ++ V D K + S ++ D+++D Sbjct: 18 LDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQA--SLEDEWRDLKGRADINKDD 75 Query: 130 KISRHEMLQVLRLMVGVQVTEEQL----ENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 +S E L + + + L +N + D GDG V EF + Sbjct: 76 VVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIVDLEEFQNYCKNFQ 135 Query: 186 VE 187 ++ Sbjct: 136 LQ 137 >2LUC-A nrPDB Length = 105 Score = 39.7 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 114 NKLHYAFQLYDLDRDGK---ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 L FQ Y +DG +S+ E L + + ++ + DR +++ D + DG Sbjct: 15 ESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDG 73 Query: 171 AVSFVEFT 178 + F EF Sbjct: 74 QLDFSEFL 81 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 28/77 (36%), Gaps = 13/77 (16%) Query: 24 SQASLLRLHHRFRALDRNKKGY---LSRMDLQQIGAL---------AVNPLGDRIIESFF 71 ++ + L F+ K GY LS+ + + DR+++ Sbjct: 10 TERCIESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLD 68 Query: 72 PDGSQRVDFPGFVRVLA 88 + ++DF F+ ++ Sbjct: 69 TNSDGQLDFSEFLNLIG 85 >4MSP-A nrPDB Length = 200 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 117 HYAFQLYDLDRDGKISRHEMLQVLRLMV---GVQVTEEQLENIADRTVQEADEDGDGAVS 173 H +FQ DL+ D K+S+ E+ L+ G V E + + + + DED DG +S Sbjct: 130 HESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFIS 189 Query: 174 FVEFT 178 EFT Sbjct: 190 AREFT 194 >2I18-A nrPDB Length = 64 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 9/64 (14%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 L ++L D+D DGK+++ E+ + +V E+ + +AD +GDG ++ Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVM---------KADANGDGYITLE 57 Query: 176 EFTK 179 EF + Sbjct: 58 EFLE 61 Score = 29.7 bits (65), Expect = 0.84, Method: Composition-based stats. Identities = 6/55 (10%), Positives = 18/55 (32%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 L ++ +D + G L++ ++ + +G + F+ Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLE 61 >5MRA-A nrPDB Length = 167 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 45/151 (29%), Gaps = 39/151 (25%) Query: 43 KGYLSRMDLQQIGAL-----AVNPLGDRIIESF----FPDGSQRVDFPGFVRVLAHFRPV 93 G + +LQ+ P D S + F F + A Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 94 EDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL 153 F +D DR G + E+ + L M G +++ + + Sbjct: 75 RQH-----------------------FISFDTDRSGTVDPQELQKALTTM-GFRLSPQAV 110 Query: 154 ENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +IA R +G ++F ++ K+ Sbjct: 111 NSIAKR------YSTNGKITFDDYIACCVKL 135 Score = 30.8 bits (68), Expect = 0.34, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 24/69 (34%), Gaps = 4/69 (5%) Query: 31 LHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 F + D ++ G + +LQ ++P I + + ++ F ++ Sbjct: 74 WRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYST-NGKITFDDYIACC 132 Query: 88 AHFRPVEDE 96 R + D Sbjct: 133 VKLRALTDS 141 Score = 30.5 bits (67), Expect = 0.45, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 13/85 (15%) Query: 13 DGDSIRRETGFSQASLLRLHHRFR---------ALDRNKKGYLSRMDLQQIGALAVNPLG 63 D D ++R +Q+ + + F LDR+ G + + +++ A+ +N Sbjct: 19 DADELQR--CLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAV-LNGWR 75 Query: 64 DRIIESFFPDGSQRVDFPGFVRVLA 88 I F D S VD + L Sbjct: 76 QHFIS-FDTDRSGTVDPQELQKALT 99 >1KFU-L nrPDB Length = 699 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 66/189 (34%), Gaps = 19/189 (10%) Query: 14 GDSIRRETGFSQASLLRLHHRFRALDRNK---KGYLSRMDLQQIGALAVNPLGDRII--E 68 + + +T L F +R + +++ ++ L P G+ I+ Sbjct: 436 PEELSGQTNI------HLSKNFFLTNRARERSDTFINLREVLNRFKL---PPGEYILVPS 486 Query: 69 SFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRD 128 +F P+ F A ++ V D++ E + + + + F D Sbjct: 487 TFEPNKDGDFCIRVFSEKKADYQAV-DDEIEANLEEFDISEDDIDDGVRRLFAQL-AGED 544 Query: 129 GKISRHEMLQVLRLMVGVQ---VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 +IS E+ +LR ++ + ++ V D DG G + EF K+ Sbjct: 545 AEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQ 604 Query: 186 VEQKMSIRI 194 QK+ I Sbjct: 605 KYQKIYREI 613 Score = 30.8 bits (68), Expect = 0.38, Method: Composition-based stats. Identities = 30/201 (14%), Positives = 65/201 (32%), Gaps = 43/201 (21%) Query: 4 RSSHAAVIPDGDSIRRETGFSQASLLR-LHHRFRALDRNKKGYLSRMDLQQI-------- 54 ++ + AV + ++ E S+ + + F L + +S +LQ I Sbjct: 505 KADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL-AGEDAEISAFELQTILRRVLAKR 563 Query: 55 ---GALAVN-PLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLN 110 + + +++ DGS ++ F L Sbjct: 564 QDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYI-----------------------LW 600 Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ K ++ D+DR G ++ +EM + L QL + D Sbjct: 601 TKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPC--QLHQVIVARFA----DDQL 654 Query: 171 AVSFVEFTKSLEKMDVEQKMS 191 + F F + L +++ K+ Sbjct: 655 IIDFDNFVRCLVRLETLFKIF 675 >1TTX-A nrPDB Length = 109 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 31/87 (35%), Gaps = 2/87 (2%) Query: 95 DEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLE 154 D + + N++ F+ D D+ G + E+ L+ + E Sbjct: 23 DTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESE 82 Query: 155 NIADRTVQEADEDGDGAVSFVEFTKSL 181 + AD DGDG + EF + + Sbjct: 83 --TKSLMAAADNDGDGKIGAEEFQEMV 107 Score = 32.4 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 33/83 (39%), Gaps = 11/83 (13%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR------- 65 + + +G S+ S ++ FR +D ++ GYL +L+ L G R Sbjct: 26 EPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELK--FFLQKFESGARELTESET 83 Query: 66 --IIESFFPDGSQRVDFPGFVRV 86 ++ + DG ++ F + Sbjct: 84 KSLMAAADNDGDGKIGAEEFQEM 106 >1QLS-A nrPDB Length = 99 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 25/52 (48%) Query: 127 RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 + KIS+ E L + + ++ + DR +++ D D DG + F EF Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFL 79 >2M7M-A nrPDB Length = 66 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 26/60 (43%), Gaps = 5/60 (8%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+ D++ DG +S E+ + ++ E + + D DG+G + EF K Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKN-----EQLLQLIFKSIDADGNGEIDQNEFAK 60 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 32 HHRFRALDRNKKGYLSRMDLQ----QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVL 87 F+ +D N G +S +++ + A+ L I +S DG+ +D F + Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 88 A 88 Sbjct: 63 G 63 Score = 29.3 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 10/21 (47%), Positives = 15/21 (71%) Query: 156 IADRTVQEADEDGDGAVSFVE 176 +A+ +E D +GDGAVS+ E Sbjct: 1 MAEALFKEIDVNGDGAVSYEE 21 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 25/73 (34%), Gaps = 17/73 (23%) Query: 63 GDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQL 122 + + + +G V + ++ R +++ L F+ Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKN-----------------EQLLQLIFKS 44 Query: 123 YDLDRDGKISRHE 135 D D +G+I ++E Sbjct: 45 IDADGNGEIDQNE 57 >1KFX-S nrPDB Length = 184 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 33/107 (30%), Gaps = 26/107 (24%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF---FPDGSQRVDFPGFV 84 + R ++ D ++ G + +L A L + + + D S +DF F+ Sbjct: 87 IKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFI 146 Query: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 L + AF+ D D G+I Sbjct: 147 SCLVRLDAMFR-----------------------AFKSLDKDGTGQI 170 Score = 31.6 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 27/193 (13%), Positives = 56/193 (29%), Gaps = 62/193 (32%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQI--------GALAVNPLG----DRIIESFFPD 73 + + F L + +S +L I L + G ++ D Sbjct: 12 EEVRQFRRLFAQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 70 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 + ++ F F + L + + ++ +D DR G I Sbjct: 71 TTGKLGFEEF-----------------------KYLWNNIKRWQAIYKQFDTDRSGTICS 107 Query: 134 HE-----------MLQVLRLMVGVQVTEEQLENIAD-------------RTVQEADEDGD 169 E + + L M+ + ++E D R + D+DG Sbjct: 108 SELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGT 167 Query: 170 GAV--SFVEFTKS 180 G + + E+ + Sbjct: 168 GQIQVNIQEWLQL 180 >2NLN-A nrPDB Length = 108 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 32/101 (31%), Gaps = 2/101 (1%) Query: 81 PGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVL 140 + D + + +++ F+ D D+ G + E+ L Sbjct: 8 AEDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFL 67 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + + E + AD DGDG + EF + + Sbjct: 68 QKFQSDARELTESE--TKSLMDAADNDGDGKIGADEFQEMV 106 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 33/81 (40%), Gaps = 7/81 (8%) Query: 13 DGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD-------R 65 + + +G S+ S ++ FR +D ++ GYL +L+ + + Sbjct: 25 EPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKS 84 Query: 66 IIESFFPDGSQRVDFPGFVRV 86 ++++ DG ++ F + Sbjct: 85 LMDAADNDGDGKIGADEFQEM 105 >3DF0-A nrPDB Length = 714 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 56/157 (35%), Gaps = 10/157 (6%) Query: 43 KGYLSRMDLQQIGALAVNPLGDRII--ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTET 100 +++ ++ L P G+ ++ +F P + F A ++ V D++ E Sbjct: 463 DTFINLREVLNRFKL---PPGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTV-DDEIEA 518 Query: 101 QDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQ---VTEEQLENIA 157 + + F D +IS E+ +LR ++ + ++ Sbjct: 519 NIEEIEANEEDIGDGFRRLFAQL-AGEDAEISAFELQTILRRVLAKREDIKSDGFSIETC 577 Query: 158 DRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRI 194 V DEDG G + EF K+ QK+ I Sbjct: 578 KIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREI 614 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 43/126 (34%), Gaps = 29/126 (23%) Query: 66 IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDL 125 +++ DGS ++ F L ++ K ++ D+ Sbjct: 580 MVDMLDEDGSGKLGLKEFYI-----------------------LWTKIQKYQKIYREIDV 616 Query: 126 DRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 DR G ++ +EM + L QL + D + + F F + L +++ Sbjct: 617 DRSGTMNSYEMRKALEEAGFKLPC--QLHQVIVARFA----DDELIIDFDNFVRCLVRLE 670 Query: 186 VEQKMS 191 + K+ Sbjct: 671 ILFKIF 676 >4OKH-A nrPDB Length = 189 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 41/133 (30%), Gaps = 28/133 (21%) Query: 4 RSSHAAVIPDGDSIRRETGFSQ--ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNP 61 RS A + DG F + F+ D ++ G ++ +++ A Sbjct: 58 RSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFH 117 Query: 62 LGDRIIESF---FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHY 118 L +++ + + D +DF F+ + Sbjct: 118 LNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFR----------------------- 154 Query: 119 AFQLYDLDRDGKI 131 AF +D D DG I Sbjct: 155 AFHAFDKDGDGII 167 Score = 35.1 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 25/165 (15%), Positives = 47/165 (28%), Gaps = 42/165 (25%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD------------RIIESFFPD 73 + + F+ + + + +L+++ VN D +I D Sbjct: 9 EEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTD 67 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 GS +++ F K+ F+ YD D+ G I+ Sbjct: 68 GSGKLNLQEF--------------------HHLWNKIKAWQKI---FKHYDTDQSGTINS 104 Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 +EM + QL +I D + F F Sbjct: 105 YEMRNAVNDAGFHL--NNQLYDIITMRYA----DKHMNIDFDSFI 143 Score = 33.5 bits (75), Expect = 0.059, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 33/90 (36%), Gaps = 4/90 (4%) Query: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADR---TV 161 + + + + F+ D D +I E+ +VL +V + + + Sbjct: 3 SSDQESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMI 61 Query: 162 QEADEDGDGAVSFVEFTKSLEKMDVEQKMS 191 D DG G ++ EF K+ QK+ Sbjct: 62 ALMDTDGSGKLNLQEFHHLWNKIKAWQKIF 91 >2FCE-A nrPDB Length = 70 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 36/69 (52%), Gaps = 5/69 (7%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 ++ AFQ++D + GK+S ++ +L + G ++T+ + D ++ + D +G Sbjct: 2 AKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGL-GEKLTDAE----VDELLKGVEVDSNG 56 Query: 171 AVSFVEFTK 179 + + +F + Sbjct: 57 EIDYKKFIE 65 Score = 29.7 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 25/65 (38%), Gaps = 4/65 (6%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQ-QIGALAVNPLG---DRIIESFFPDGSQRVDF 80 +A F+ D+ G +S DL+ + L D +++ D + +D+ Sbjct: 1 KAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDY 60 Query: 81 PGFVR 85 F+ Sbjct: 61 KKFIE 65 >1NSH-A nrPDB Length = 101 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Query: 114 NKLHYAFQLYDLDRDG---KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 L FQ Y +DG +S+ E L + + ++ + DR +++ D + DG Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDG 69 Query: 171 AVSFVEFTKSLEKMDV 186 + F EF + + V Sbjct: 70 QLDFQEFLNLIGGLAV 85 Score = 27.0 bits (58), Expect = 6.1, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 28/77 (36%), Gaps = 13/77 (16%) Query: 24 SQASLLRLHHRFRALDRNKKGY---LSRMDLQQIGAL---------AVNPLGDRIIESFF 71 ++ + L F+ K G+ LS+ + + DR+++ Sbjct: 6 TERCIESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLD 64 Query: 72 PDGSQRVDFPGFVRVLA 88 + ++DF F+ ++ Sbjct: 65 LNSDGQLDFQEFLNLIG 81 >5VT9-A nrPDB Length = 152 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 54/156 (34%), Gaps = 27/156 (17%) Query: 27 SLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPLGDRIIESFFPDGSQRVDFPGFVR 85 ++ RF A R G +S D + L + P ++F +D+ F + Sbjct: 18 EADEMYARFNA--RASGGKVSTGDAMILARQLGLAPSYADK-QAFEEKSGDNLDYASFQK 74 Query: 86 VLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVG 145 + ED L AF +D+ + G ++R +M +L G Sbjct: 75 FVGTSTHPEDNI----------------EDLVEAFAYFDVSKHGYLTRKQMGNILMT-YG 117 Query: 146 VQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 +T E+ +A + + +F K++ Sbjct: 118 EPLTTEEFNALAAEYFT------SDQIDYRQFCKAM 147 Score = 33.2 bits (74), Expect = 0.083, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPD--GSQRVDFPG 82 + ++ L F D +K GYL+R + I PL + + S ++D+ Sbjct: 83 EDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTEEFNALAAEYFTSDQIDYRQ 142 Query: 83 FVRVL 87 F + + Sbjct: 143 FCKAM 147 >5HYD-A nrPDB Length = 99 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 30/57 (52%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 K+S+ E+ +L+ + ++ ++ + D+ VQ+ D + D V F EF + + V Sbjct: 28 KLSKGELKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALTV 84 >4I5L-B nrPDB Length = 413 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 70/206 (33%), Gaps = 28/206 (13%) Query: 8 AAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRII 67 A + + D + FS ++ +F LD + + DL + + L ++I Sbjct: 177 ALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLAR---HNDHALSTKMI 233 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 + F S V R + + + E + Y F+ DLD Sbjct: 234 DRIF---SGAV-----TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDG 285 Query: 128 DGKISRHEM----LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS---------- 173 DG +S E+ + R + + + ++ + + +G ++ Sbjct: 286 DGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLA 345 Query: 174 ---FVEFTKSLEKMDVEQKMSIRILK 196 F F + +D EQK I +L+ Sbjct: 346 NVFFDTFFNIEKYLDHEQKEQISLLR 371 Score = 30.5 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 27/173 (15%), Positives = 62/173 (35%), Gaps = 14/173 (8%) Query: 12 PDGDSIRRETGFSQASLL-RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF 70 P ++ + F + + F A++R+ G ++ +L++ L L + Sbjct: 127 PGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE----- 181 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 D +Q +F + + + DT+ + L + ++ D G Sbjct: 182 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALST-KMIDRIFSGA 240 Query: 131 ISR----HEMLQVLRLMVGVQVTEEQLENI---ADRTVQEADEDGDGAVSFVE 176 ++R + ++ + E+ + + + D DGDGA+S E Sbjct: 241 VTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFE 293 >1CB1-A nrPDB Length = 78 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +S+ E+ Q+++ + + D QE D++GDG VSF EF ++K+ Sbjct: 26 LSKEELKQLIQA---EFPSLLKGPRTLDDLFQELDKNGDGEVSFEEFQVLVKKI 76 Score = 30.1 bits (66), Expect = 0.63, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 19/63 (30%), Gaps = 8/63 (12%) Query: 29 LRLHHRFRAL--DRNKKGYLSRMDLQQI------GALAVNPLGDRIIESFFPDGSQRVDF 80 L F LS+ +L+Q+ L D + + +G V F Sbjct: 7 AELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSF 66 Query: 81 PGF 83 F Sbjct: 67 EEF 69 Score = 27.0 bits (58), Expect = 4.9, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 23/64 (35%) Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F + + E+ + + L L FQ D + DG++S E + Sbjct: 13 FEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFEEFQVL 72 Query: 140 LRLM 143 ++ + Sbjct: 73 VKKI 76 >1GJY-A nrPDB Length = 167 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 43/151 (28%), Gaps = 39/151 (25%) Query: 43 KGYLSRMDLQQIGAL-----AVNPLGDRIIESF----FPDGSQRVDFPGFVRVLAHFRPV 93 G + +LQ+ P D S + F F + A Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 94 EDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL 153 F +D DR G + E+ + L M G ++ + + Sbjct: 75 RQH-----------------------FISFDSDRSGTVDPQELQKALTTM-GFRLNPQTV 110 Query: 154 ENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +IA R G ++F ++ K+ Sbjct: 111 NSIAKR------YSTSGKITFDDYIACCVKL 135 Score = 31.6 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 31 LHHRFRALDRNKKGYLSRMDLQ---QIGALAVNP-LGDRIIESFFPDGSQRVDFPGFVRV 86 F + D ++ G + +LQ +NP + I + + S ++ F ++ Sbjct: 74 WRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYST--SGKITFDDYIAC 131 Query: 87 LAHFRPVEDE 96 R + D Sbjct: 132 CVKLRALTDS 141 Score = 30.5 bits (67), Expect = 0.52, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 35/96 (36%), Gaps = 11/96 (11%) Query: 2 GSRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFR---------ALDRNKKGYLSRMDLQ 52 G +S A D+ + +Q+ + + F LDR+ G + + + Sbjct: 6 GYFASVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFK 65 Query: 53 QIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLA 88 ++ A+ +N I F D S VD + L Sbjct: 66 ELWAV-LNGWRQHFIS-FDSDRSGTVDPQELQKALT 99 >2HPS-A nrPDB Length = 186 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 61/156 (39%), Gaps = 12/156 (7%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQI-----GALAVNPLGDRIIESFFPDGSQRVDFPG 82 L ++ R + +D G++SR D + I ++ F + ++ Sbjct: 13 LRKMKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAP 72 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 VR+ V D+ + + + + ++ + Y D D+DG +S E L+ Sbjct: 73 GVRISVEEAAVNATDSLLKMKGEEKAMAVIQSLIMY--DCIDTDKDGYVSLPEFKAFLQA 130 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 VG +T+++ A D + +G +S EF Sbjct: 131 -VGPDLTDDK----AITCFNTLDFNKNGQISRDEFL 161 Score = 27.0 bits (58), Expect = 5.5, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 2/47 (4%) Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 L M G + ++++ D D DG VS EF L+ + Sbjct: 87 DSLLKMKGEEKAMAVIQSLI--MYDCIDTDKDGYVSLPEFKAFLQAV 131 >3CS1-A nrPDB Length = 219 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 26/168 (15%), Positives = 54/168 (32%), Gaps = 35/168 (20%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDL--QQIGALAVNPLGDRIIE----SFFP----- 72 + + R F+ D+N+ G L ++ + L ++ R+ + +F Sbjct: 43 TAEAKQRRIELFKKFDKNETGKLCYDEVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLG 102 Query: 73 ---DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDG 129 + DF F+ + D +L F D + Sbjct: 103 SKLENKGSEDFVEFLEFRLMLCYIYDFF-----------------ELTVMFDEIDASGNM 145 Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 + E + + + E + +E D++G G+V+F EF Sbjct: 146 LVDEEEFKRAVPKLEAWGAKVEDPAAL----FKELDKNGTGSVTFDEF 189 Score = 32.8 bits (73), Expect = 0.098, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 25/75 (33%), Gaps = 9/75 (12%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQ-------IGALAVNPLGDRIIESFFPDGSQRVDFPG 82 L F +D + + + ++ GA +P + + +G+ V F Sbjct: 131 ELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDP--AALFKELDKNGTGSVTFDE 188 Query: 83 FVRVLAHFRPVEDED 97 F + + D D Sbjct: 189 FAAWASAVKLDADGD 203 Score = 27.0 bits (58), Expect = 5.5, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 13/26 (50%) Query: 160 TVQEADEDGDGAVSFVEFTKSLEKMD 185 E D G+ V EF +++ K++ Sbjct: 135 MFDEIDASGNMLVDEEEFKRAVPKLE 160 >1BOD-A nrPDB Length = 74 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 +L F+ YD + DG++S+ E+ +L+ + + + D +E D++GDG Sbjct: 2 KSPEELKGIFEKYDKEGDGQLSKEELKLLLQT---EFPSLLKGMSTLDELFEELDKNGDG 58 Query: 171 AVSFVEFTKSLEKM 184 VSF EF ++K+ Sbjct: 59 EVSFEEFQVLVKKI 72 Score = 29.7 bits (65), Expect = 0.77, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 21/61 (34%), Gaps = 6/61 (9%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGA------LAVNPLGDRIIESFFPDGSQRVDFPG 82 L F D+ G LS+ +L+ + L D + E +G V F Sbjct: 5 EELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSFEE 64 Query: 83 F 83 F Sbjct: 65 F 65 >6MI5-X nrPDB Length = 117 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 32/110 (29%), Gaps = 21/110 (19%) Query: 67 IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLD 126 I +F PD +D + + D D + K L D D Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEADLKK----LDPD 64 Query: 127 RDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVE 176 DG + + E L + + + A+ D DG + E Sbjct: 65 NDGTLDKKEYLAAV-----------------EAQFKAANPDNDGTIDARE 97 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 30/100 (30%), Gaps = 12/100 (12%) Query: 37 ALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDE 96 A D +K G + + G + PD +D ++ + + Sbjct: 11 AFDPDKDGTIDLKEALA--------AGSAAFDKLDPDKDGTLDAKELKGRVSEADLKKLD 62 Query: 97 DTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM 136 K E L + + A + D DG I E+ Sbjct: 63 PDNDGTLDKKEYLAAVEAQFKAA----NPDNDGTIDAREL 98 Score = 35.1 bits (79), Expect = 0.020, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 36/106 (33%), Gaps = 11/106 (10%) Query: 3 SRSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPL 62 ++ AA PD + T + +L F LD +K G L +L+ + A Sbjct: 5 TKVDIAAFDPD----KDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEAD--- 57 Query: 63 GDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEP 108 ++ PD +D ++ + + D + + Sbjct: 58 ----LKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDARELA 99 >5VP3-A nrPDB Length = 206 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 58/171 (33%), Gaps = 26/171 (15%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGALA---VNPLGDRIIES-------FFPDGS 75 L RL+ RF D + G ++ ++ VN +++ + FF G Sbjct: 31 KMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGV 90 Query: 76 QRVD---FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKIS 132 V+ +V F E E +P L++ + + D D DG + Sbjct: 91 DPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLSN------AYYDVLDDDGDGTVD 144 Query: 133 RHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 E+ +++ + + A Q+AD D G + E K Sbjct: 145 VEELKTMMKAF-------DVPQEAAYTFFQKADTDKTGKLERPELVHLFRK 188 >4L9M-A nrPDB Length = 559 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 18/65 (27%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVE--- 176 F+ YD D+DG IS+ E E++ + D+D +G +S E Sbjct: 431 FKNYDHDQDGYISQEEF--------------EKIAASFPFSFCVMDKDREGLISRDEITA 476 Query: 177 -FTKS 180 F ++ Sbjct: 477 YFMRA 481 Score = 33.5 bits (75), Expect = 0.055, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKS 180 ++ + D + D D DG +S EF K Sbjct: 423 VQRMVDSVFKNYDHDQDGYISQEEFEKI 450 Score = 30.5 bits (67), Expect = 0.52, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 34/93 (36%), Gaps = 15/93 (16%) Query: 5 SSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGD 64 +S + PD +I + Q + F+ D ++ GY+S+ + ++I A P Sbjct: 407 ASGVSPKPDPKTISKHV---QRMVD---SVFKNYDHDQDGYISQEEFEKIAA--SFPFS- 457 Query: 65 RIIESFFPDGSQRVDFPG----FVRVLAHFRPV 93 D + F+R + + + Sbjct: 458 --FCVMDKDREGLISRDEITAYFMRASSIYSKL 488 Score = 30.1 bits (66), Expect = 0.59, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 26/73 (35%), Gaps = 26/73 (35%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 D + +++ D + F ++ A F ++F + Sbjct: 428 DSVFKNYDHDQDGYISQEEFEKIAASFP--------------------------FSFCVM 461 Query: 124 DLDRDGKISRHEM 136 D DR+G ISR E+ Sbjct: 462 DKDREGLISRDEI 474 >4MEW-A nrPDB Length = 356 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 45/129 (34%), Gaps = 11/129 (8%) Query: 8 AAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRII 67 A + + D + FS ++ +F LD + + DL + + L ++I Sbjct: 169 ALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLAR---HNDHALSTKMI 225 Query: 68 ESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDR 127 + F S V R + + + E + Y F+ DLD Sbjct: 226 DRIF---SGAV-----TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDG 277 Query: 128 DGKISRHEM 136 DG +S E+ Sbjct: 278 DGALSMFEL 286 Score = 29.3 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 27/173 (15%), Positives = 62/173 (35%), Gaps = 14/173 (8%) Query: 12 PDGDSIRRETGFSQASLL-RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF 70 P ++ + F + + F A++R+ G ++ +L++ L L + Sbjct: 119 PGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE----- 173 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 D +Q +F + + + DT+ + L + ++ D G Sbjct: 174 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALST-KMIDRIFSGA 232 Query: 131 ISR----HEMLQVLRLMVGVQVTEEQLENI---ADRTVQEADEDGDGAVSFVE 176 ++R + ++ + E+ + + + D DGDGA+S E Sbjct: 233 VTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFE 285 >5CSF-A nrPDB Length = 95 Score = 36.2 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 26/49 (53%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 K+ + E+ +++ + + E + + + D+ ++ D DGDG F EF Sbjct: 30 KLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFM 78 Score = 26.6 bits (57), Expect = 7.4, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 19/43 (44%) Query: 46 LSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLA 88 ++ + + + D+++E+ DG DF F+ +A Sbjct: 40 INNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVA 82 >2KGR-A nrPDB Length = 111 Score = 35.9 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 7/79 (8%) Query: 111 SRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDG 170 S R K F +D G ++ + +L + + +D D DG Sbjct: 11 SSRLKYRQLFNSHDKTMSGHLTGPQARTIL-------MQSSLPQAQLASIWNLSDIDQDG 63 Query: 171 AVSFVEFTKSLEKMDVEQK 189 ++ EF ++ +DV Sbjct: 64 KLTAEEFILAMHLIDVAMS 82 >2M7L-A nrPDB Length = 144 Score = 35.5 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 12/101 (11%), Positives = 28/101 (27%), Gaps = 9/101 (8%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQ------IGALAVNPLGDRIIESF--- 70 +G + + F A D N G L +++ + + + D ++ Sbjct: 3 SSGVTAEQMQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNN 62 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNS 111 G V F +V+ + + + Sbjct: 63 VTKGENGVSFDNYVQYMKEKNDENPSPEQLNEIFSTIAAGK 103 Score = 29.7 bits (65), Expect = 0.93, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 30/74 (40%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 + +F +D + DG + + E L M + + E+ + G+ VS Sbjct: 12 QEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNNVTKGENGVS 71 Query: 174 FVEFTKSLEKMDVE 187 F + + +++ + E Sbjct: 72 FDNYVQYMKEKNDE 85 >5W1A-B nrPDB Length = 155 Score = 35.5 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 23/164 (14%), Positives = 59/164 (35%), Gaps = 20/164 (12%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIE--SFFPDGSQRVDFPG 82 + + + F + +G + + AL +NP I + +++ Sbjct: 6 KREVENVEFVFEVMGSPGEGIDAVDLGDALRALNLNPTLALIEKLGGTKKRNEKKIKLDE 65 Query: 83 FVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 F+ + + + +++ +LYD + +G + E+ L Sbjct: 66 FLPIYSQVKKEKEQGCY--------------EDFIECLKLYDKEENGTMLLAELQHALLA 111 Query: 143 MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT-KSLEKMD 185 + G + +EQ+E + + ED +G + + F + ++ D Sbjct: 112 L-GESLDDEQVETLFADCMD--PEDDEGFIPYSPFLARMCDRPD 152 >4I5K-A nrPDB Length = 285 Score = 34.7 bits (78), Expect = 0.028, Method: Composition-based stats. Identities = 32/173 (18%), Positives = 61/173 (35%), Gaps = 16/173 (9%) Query: 7 HAAVIPDGDSIRRETG-FSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDR 65 A++ + + I + T FS ++ +F LD + Y+S+ DL + R Sbjct: 93 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRY---NDQASSSR 149 Query: 66 IIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDL 125 IIE F S V R + + E + Y F+ D+ Sbjct: 150 IIERIF---SGAV-----TRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDV 201 Query: 126 DRDGKISRHEM----LQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 D DG +S +E+ + M + + ++ + + DG ++ Sbjct: 202 DGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITL 254 Score = 26.2 bits (56), Expect = 9.2, Method: Composition-based stats. Identities = 26/173 (15%), Positives = 59/173 (34%), Gaps = 20/173 (11%) Query: 29 LRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLA 88 + F ++R+ G ++ ++++ L L + E + + F + Sbjct: 63 TVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEE--EEDINQITDYFSYEHFYVIYC 120 Query: 89 HFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR-----HEMLQVLRLM 143 F ++ + N + + +++ G ++R E Sbjct: 121 KFWELDTDHDLYISQADLSRYNDQASSSRIIERIF----SGAVTRGKTIQKEGRMSYADF 176 Query: 144 VGVQVTEEQLEN--IADRTVQEADEDGDGAVS-------FVEFTKSLEKMDVE 187 V ++EE N + + D DGDG +S + E + +E M +E Sbjct: 177 VWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIE 229 >2MBX-A nrPDB Length = 109 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 116 LHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFV 175 + F++ D D+ + E+ L+ E ++ D DGDG + Sbjct: 44 IKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAE--TKVFLKAGDSDGDGKIGVD 101 Query: 176 EFTKSLE 182 EF ++ Sbjct: 102 EFGAMIK 108 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 7/75 (9%) Query: 20 ETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQ---QIGALAVNPLGDRIIESF----FP 72 + G + S + F +D++K ++ +L+ Q + L D + F Sbjct: 33 KVGLAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDS 92 Query: 73 DGSQRVDFPGFVRVL 87 DG ++ F ++ Sbjct: 93 DGDGKIGVDEFGAMI 107 >2Y5I-A nrPDB Length = 99 Score = 34.3 bits (77), Expect = 0.032, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 28/57 (49%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 K+S+ E+ ++L + + ++ + ++ + + D + D V F EF + + V Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAALTV 84 >1KQV-A nrPDB Length = 79 Score = 34.3 bits (77), Expect = 0.039, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 19/30 (63%) Query: 155 NIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + D +E D++GDG VSF EF ++K+ Sbjct: 48 STLDELFEELDKNGDGEVSFEEFQVLVKKI 77 >6AGH-A nrPDB Length = 339 Score = 33.5 bits (75), Expect = 0.052, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 45/132 (34%), Gaps = 1/132 (0%) Query: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF 70 I + + ++ G S + + ++++ + + D +SF Sbjct: 204 IQEMEFLQFSKGLSFMRKEDFAEWLLFFTNTENKDIYWKNVREKLSAGESISLDE-FKSF 262 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 + DF +++ + + K N L F+++DLD D Sbjct: 263 CHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDEC 322 Query: 131 ISRHEMLQVLRL 142 +S E L VL+ Sbjct: 323 LSHEEFLGVLKN 334 Score = 27.8 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 E + +++ G +++ NI D + D DGD +S EF L+ Sbjct: 289 AEFKRAVKVATGQELSN----NILDTVFKIFDLDGDECLSHEEFLGVLKN 334 >4C0K-A nrPDB Length = 423 Score = 33.5 bits (75), Expect = 0.058, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 45/154 (29%), Gaps = 35/154 (22%) Query: 17 IRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVN-PLGDRIIESF----- 70 + E + A L F+ D + L+ +L N PL +I++ Sbjct: 1 MMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQ 60 Query: 71 --FPDG--SQRVDFPGFV---RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLH------ 117 PDG + V GF+ + E + + L + L Sbjct: 61 KNVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKIP 120 Query: 118 ----------------YAFQLYDLDRDGKISRHE 135 F+ YD D DG +S E Sbjct: 121 PGSSTELSHRGQQFLIAVFERYDRDGDGALSPEE 154 Score = 30.5 bits (67), Expect = 0.49, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 17/48 (35%), Gaps = 4/48 (8%) Query: 9 AVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGA 56 IP G T S L F DR+ G LS + + + + Sbjct: 117 LKIPPG----SSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFS 160 >4P5W-A nrPDB Length = 411 Score = 33.5 bits (75), Expect = 0.060, Method: Composition-based stats. Identities = 24/169 (14%), Positives = 52/169 (30%), Gaps = 32/169 (18%) Query: 29 LRLHHRFRA---LDRNKKGYLSRMDLQQIG-----ALAVNPLGDRIIE-SFFPDGSQRVD 79 L F +++N + ++S D NP ++ + Sbjct: 37 AELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLIS 96 Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQV 139 F FV L + AFQL+D G+++ ++ QV Sbjct: 97 FQEFVA-------------------FESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQV 137 Query: 140 L-RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVE 187 + + + + + +++ EFT+ L ++ +E Sbjct: 138 FGQTTIHQHIPFNWDSEFVQLHFGKERKRH---LTYAEFTQFLLEIQLE 183 Score = 27.4 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 25/65 (38%), Gaps = 7/65 (10%) Query: 124 DLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 D +DG IS E + ++ + + Q D+ G G V+F + + + Sbjct: 88 DQTKDGLISFQEFVAFESVLCA-------PDALFMVAFQLFDKAGKGEVTFEDVKQVFGQ 140 Query: 184 MDVEQ 188 + Q Sbjct: 141 TTIHQ 145 >2MJW-B nrPDB Length = 94 Score = 33.2 bits (74), Expect = 0.076, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 25/48 (52%) Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 +++ E+ ++ + + + ++ D+ +++ D +GD V F EF Sbjct: 28 LTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFI 75 >1F4Q-A nrPDB Length = 165 Score = 33.2 bits (74), Expect = 0.079, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 50/151 (33%), Gaps = 39/151 (25%) Query: 43 KGYLSRMDLQQ-IGALAVN----PLGDR----IIESFFPDGSQRVDFPGFVRVLAHFRPV 93 G + +LQ+ + +N P +I D + ++ F F + A Sbjct: 13 DGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAW 72 Query: 94 EDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQL 153 ++ F D D G + HE+ Q + ++G +++ + L Sbjct: 73 KEN-----------------------FMTVDQDGSGTVEHHELRQAI-GLMGYRLSPQTL 108 Query: 154 ENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 I R +G + F ++ K+ Sbjct: 109 TTIVKR------YSKNGRIFFDDYVACCVKL 133 Score = 30.1 bits (66), Expect = 0.68, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 26/70 (37%), Gaps = 2/70 (2%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFP--DGSQRVDFPGFVR 85 L F +D++ G + +L+Q L L + + + + R+ F +V Sbjct: 69 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA 128 Query: 86 VLAHFRPVED 95 R + D Sbjct: 129 CCVKLRALTD 138 Score = 29.3 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 20/55 (36%), Gaps = 2/55 (3%) Query: 127 RDGKISRHEMLQVLRLMVGVQVTEEQLE-NIADRTVQEADEDGDGAVSFVEFTKS 180 +DG++ E+ + L G+ T + D D G + F F + Sbjct: 12 QDGEVDAEELQRCLTQ-SGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKEL 65 >6EAZ-A nrPDB Length = 379 Score = 33.2 bits (74), Expect = 0.081, Method: Composition-based stats. Identities = 20/148 (13%), Positives = 53/148 (35%), Gaps = 1/148 (0%) Query: 11 IPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF 70 + + + ++ G + + + ++++ ++ + D +SF Sbjct: 207 VQEMEFLQFSKGLNFMRKEDFAEWLLFFTNTENKDIYWRNVREKLSVGESISLDE-FKSF 265 Query: 71 FPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGK 130 + DF +++ + + K N L F+++DLD D Sbjct: 266 CHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDEC 325 Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIAD 158 +S E L VL+ + + Q +++ + Sbjct: 326 LSHGEFLGVLKNRMHRGLWVSQQQSVQE 353 Score = 31.6 bits (70), Expect = 0.24, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 39/95 (41%), Gaps = 14/95 (14%) Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHE---MLQVLRLMVGVQVTEEQLENIADRTVQEAD 165 L + H AF++ D+D + I R E + +++ G + + D TV+E Sbjct: 114 LTKPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQDGFKTVKTNETEYQDPTVKEPG 173 Query: 166 ED-----------GDGAVSFVEFTKSLEKMDVEQK 189 + G+ + + EF + +E + E + Sbjct: 174 VNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQ 208 Score = 27.0 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 4/50 (8%) Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 E + +++ G ++++ N+ D + D DGD +S EF L+ Sbjct: 292 AEFKRAVKVATGQELSD----NLLDTVFKIFDLDGDECLSHGEFLGVLKN 337 >4NSC-A nrPDB Length = 401 Score = 33.2 bits (74), Expect = 0.081, Method: Composition-based stats. Identities = 19/134 (14%), Positives = 46/134 (34%), Gaps = 2/134 (1%) Query: 31 LHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHF 90 F+ D N G + + +Q+ ++ + + P + + +F Sbjct: 148 FEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYF 207 Query: 91 RPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTE 150 + + T + + L F+ +D DG+I+ + +L GVQ + Sbjct: 208 FGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDP-VDGRITERQFGGMLLAYSGVQSKK 266 Query: 151 -EQLENIADRTVQE 163 ++ + +E Sbjct: 267 LTAMQRQLKKHFKE 280 Score = 30.8 bits (68), Expect = 0.35, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 17/43 (39%) Query: 151 EQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIR 193 + + + D +GDG V EF + + + M +R Sbjct: 142 STPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMR 184 Score = 30.8 bits (68), Expect = 0.35, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 3/80 (3%) Query: 62 LGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVED-EDTETQDPKKPEPLNSRRNK-LHYA 119 L II+ F + + F + F + + D + S + A Sbjct: 93 LDQYIIKRFDGKKISQ-EREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIA 151 Query: 120 FQLYDLDRDGKISRHEMLQV 139 F+++DL+ DG++ E QV Sbjct: 152 FKMFDLNGDGEVDMEEFEQV 171 Score = 30.8 bits (68), Expect = 0.40, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 32/94 (34%), Gaps = 1/94 (1%) Query: 49 MDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEP 108 L++ + E+FF D + D+ T Q + Sbjct: 272 RQLKKHFKEGKGLTFQEV-ENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAK 330 Query: 109 LNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRL 142 + + F L+D D +G++S E + +++ Sbjct: 331 VELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQ 364 Score = 30.1 bits (66), Expect = 0.59, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Query: 136 MLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 M QV R + V++++ ++ D D DG+G +S EF +++ Sbjct: 321 MQQVARTVAKVELSD----HVCDVVFALFDCDGNGELSNKEFVSIMKQ 364 >1NUB-A nrPDB Length = 229 Score = 33.2 bits (74), Expect = 0.085, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 35/80 (43%), Gaps = 10/80 (12%) Query: 116 LHYAFQLYDLDR-DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +H+ F D DG +S E+ + ++ +E+ R + D D D ++ Sbjct: 157 VHWQFGQLDQHPIDGYLSHTELAPLRAPLI-------PMEHCTTRFFETCDLDNDKYIAL 209 Query: 175 VEF--TKSLEKMDVEQKMSI 192 E+ +++ D+++ + I Sbjct: 210 DEWAGCFGIKQKDIDKDLVI 229 >2MA2-A nrPDB Length = 81 Score = 32.8 bits (73), Expect = 0.096, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 144 VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 + + E +E + + + D DGDG +S EF Sbjct: 2 LDQALVVEHIEKMVESVFRNFDVDGDGHISQEEF 35 Score = 32.8 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 24/73 (32%), Gaps = 24/73 (32%) Query: 64 DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLY 123 + + +F DG + F + +F + AF Sbjct: 16 ESVFRNFDVDGDGHISQEEFQIIRGNFPYLS------------------------AFGDL 51 Query: 124 DLDRDGKISRHEM 136 D ++DG ISR EM Sbjct: 52 DQNQDGCISREEM 64 Score = 32.0 bits (71), Expect = 0.19, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 25/60 (41%), Gaps = 12/60 (20%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 F+ +D+D DG IS+ E Q++R + D++ DG +S E Sbjct: 19 FRNFDVDGDGHISQEE-FQIIRGNF-----------PYLSAFGDLDQNQDGCISREEMVS 66 Score = 29.7 bits (65), Expect = 0.74, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 17/69 (24%), Gaps = 3/69 (4%) Query: 32 HHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFR 91 FR D + G++S+ + Q I P + + V Sbjct: 16 ESVFRNFDVDGDGHISQEEFQIIR--GNFPYLSA-FGDLDQNQDGCISREEMVSYFLRSS 72 Query: 92 PVEDEDTET 100 V Sbjct: 73 SVLGGRMGF 81 >1WY9-A nrPDB Length = 147 Score = 32.4 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 29/68 (42%), Gaps = 9/68 (13%) Query: 118 YAFQL----YDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 AF++ +DL+ +G I + ++L ++ + R ++E + S Sbjct: 48 EAFKVKYMEFDLNGNGDIDIMSLKRML-----EKLGVPKTHLELKRLIREVSSGSEETFS 102 Query: 174 FVEFTKSL 181 + +F + + Sbjct: 103 YSDFLRMM 110 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 26/70 (37%), Gaps = 4/70 (5%) Query: 26 ASLLRLHHRFRALDRNKKGYLS----RMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFP 81 + L ++ D N G + + L+++G + R+I + + Sbjct: 45 SKLEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYS 104 Query: 82 GFVRVLAHFR 91 F+R++ R Sbjct: 105 DFLRMMLGKR 114 >5HLO-A nrPDB Length = 94 Score = 32.4 bits (72), Expect = 0.14, Method: Composition-based stats. Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 157 ADRTVQEADEDGDGAVSFVEFTKSLEKMDV 186 AD +E D + DGAV+F EF + KM V Sbjct: 52 ADVWFKELDINTDGAVNFQEFLILVIKMGV 81 >3H4S-E nrPDB Length = 135 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 25/51 (49%) Query: 138 QVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 + LR G+ E + A V+E D DGDGA++ EF + ++ E Sbjct: 60 ESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEM 110 Score = 27.0 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 27/81 (33%), Gaps = 5/81 (6%) Query: 25 QASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL-----AVNPLGDRIIESFFPDGSQRVD 79 + + L F L ++ ++ L++ + ++ DG ++ Sbjct: 36 EEFVSELCKGFSLLADPERHLITAESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGALN 95 Query: 80 FPGFVRVLAHFRPVEDEDTET 100 F ++ P ED ET Sbjct: 96 QTEFCVLMVRLSPEMMEDAET 116 >6AGI-A nrPDB Length = 382 Score = 32.0 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 55/162 (33%), Gaps = 25/162 (15%) Query: 38 LDRNKKGYLSRMDLQQIGALAVNPLGDRIIESFF---PDGSQRVDFPGFVRVLAHFRPVE 94 + K L+ D + + L ++E F +G + F +L + VE Sbjct: 217 FGKKGKAELNFEDFYRFM----DNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVE 272 Query: 95 DED--TETQDPKKPEPLNSRRNKLHYAFQLYDLDRD------------GKISRHEMLQVL 140 + E PE ++ FQ + D I + E + + Sbjct: 273 NTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAV 332 Query: 141 RLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 + G++ + ++ + + D D D +S+ EF ++ Sbjct: 333 YVATGLKFSP----HLVNTVFKIFDVDKDDQLSYKEFIGIMK 370 >3A8R-A nrPDB Length = 179 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 43/110 (39%), Gaps = 7/110 (6%) Query: 73 DGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRR--NKLHYAFQLYDLDRDGK 130 DGS F + V+ T+ + E L + N+L F + D + DG+ Sbjct: 55 DGSDEFAVQMFDSLARKRGIVKQVLTKDELKDFYEQLTDQGFDNRLRTFFDMVDKNADGR 114 Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADR----TVQEADEDGDGAVSFVE 176 ++ E+ +++ + +++ AD ++E D G + + Sbjct: 115 LTAEEVKEII-ALSASANKLSKIKERADEYTALIMEELDPTNLGYIEMED 163 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 27/70 (38%), Gaps = 12/70 (17%) Query: 30 RLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLG------------DRIIESFFPDGSQR 77 RL F +D+N G L+ ++++I AL+ + I+E P Sbjct: 99 RLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKERADEYTALIMEELDPTNLGY 158 Query: 78 VDFPGFVRVL 87 ++ +L Sbjct: 159 IEMEDLEALL 168 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 22/51 (43%), Gaps = 5/51 (9%) Query: 131 ISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 +++ E+ Q+T++ +N D++ DG ++ E + + Sbjct: 79 LTKDELKDF-----YEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEII 124 >3NSO-A nrPDB Length = 101 Score = 32.0 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 23/48 (47%) Query: 134 HEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 E+ ++L+ + E E ++ + D + D V FVE+ +SL Sbjct: 32 AELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSL 79 >6DS2-B nrPDB Length = 114 Score = 31.2 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 131 ISRHEMLQVLRLMVGVQVT-EEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 +++ E +++R + + E + E + + +++ D + D +SF EF + ++ Sbjct: 32 LNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARL 86 >1NP8-A nrPDB Length = 159 Score = 31.2 bits (69), Expect = 0.31, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 24/70 (34%), Gaps = 3/70 (4%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIESF---FPDGSQRVDFPGFV 84 + + ++ D ++ G + +L A L I + D + +DF F+ Sbjct: 83 IKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFI 142 Query: 85 RVLAHFRPVE 94 L + Sbjct: 143 SCLVRLDAMF 152 >4YBH-B nrPDB Length = 92 Score = 30.8 bits (68), Expect = 0.38, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 28/50 (56%), Gaps = 6/50 (12%) Query: 131 ISRHEMLQVLRL--MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 +S+ E+ ++++ +G ++ + ++ R +++ D + D V+F E+ Sbjct: 31 LSKKELKELIQKELTIGSKLQDAEIA----RLMEDLDRNKDQEVNFQEYV 76 >2JXC-A nrPDB Length = 100 Score = 30.5 bits (67), Expect = 0.54, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 24/54 (44%), Gaps = 7/54 (12%) Query: 128 DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 +G +S ++ VL + + +I R + +D D DG + EF ++ Sbjct: 28 NGFLSGDKVKPVL-------LNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >6DU8-A nrPDB Length = 805 Score = 30.1 bits (66), Expect = 0.60, Method: Composition-based stats. Identities = 26/167 (15%), Positives = 49/167 (29%), Gaps = 33/167 (19%) Query: 28 LLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPL-------GDRI--IESFFPDGSQRV 78 L ++ + + G + L + N +R+ ++ G Q + Sbjct: 557 LAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEI 616 Query: 79 DFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQ 138 F F L E E TE L F +D D + + E + Sbjct: 617 QFEDFTNTLRELGHAEHEITE----------------LTATFTKFDRDGNRILDEKEQEK 660 Query: 139 VLRLMVGVQVTEEQLENIADRTVQEADEDGDGA--------VSFVEF 177 + + + +V R++ + + G VS EF Sbjct: 661 MRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEF 707 >2G2B-A nrPDB Length = 150 Score = 30.1 bits (66), Expect = 0.66, Method: Composition-based stats. Identities = 11/93 (11%), Positives = 31/93 (33%), Gaps = 5/93 (5%) Query: 89 HFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV 148 + + + E L S+ + +DL+ +G I + ++L ++ Sbjct: 26 RLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRML-----EKL 80 Query: 149 TEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + + + E S+ +F + + Sbjct: 81 GVPKTHLELKKLIGEVSSGSGETFSYPDFLRMM 113 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 27/70 (38%), Gaps = 4/70 (5%) Query: 26 ASLLRLHHRFRALDRNKKGYLS----RMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFP 81 + L ++ D N G + + L+++G + ++I + +P Sbjct: 48 SKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYP 107 Query: 82 GFVRVLAHFR 91 F+R++ R Sbjct: 108 DFLRMMLGKR 117 >4MN0-A nrPDB Length = 208 Score = 30.1 bits (66), Expect = 0.71, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 53/171 (30%), Gaps = 26/171 (15%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIG---------ALAVNPLGDRIIESFFPD-GS 75 L RL+ RF D + G + ++ + FF G Sbjct: 33 KMLSRLYKRFDTFDLDSDGKMEMDEVLYWPDRMRQLVNATDEQVEKMRDAVRVFFLHKGV 92 Query: 76 QRVD---FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKIS 132 + V+ +V F E E +P L++ + + D D DG + Sbjct: 93 EPVNGLLREDWVEANRVFAEAERERERRGEPSLIALLSNS------YYDVLDDDGDGTVD 146 Query: 133 RHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEK 183 E+ +++ + + A ++AD D G + E K Sbjct: 147 VDELKTMMKAF-------DVPQEAAYTFFEKADTDKSGKLERTELVHLFRK 190 >1DJX-A nrPDB Length = 624 Score = 29.7 bits (65), Expect = 0.74, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 107 EPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADE 166 + ++ +H + D ++D K++ E+ L+ + +QV + A + +E D Sbjct: 4 DQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELN-IQVDD----GYARKIFRECDH 58 Query: 167 DGDGAVSFVE---FTKSLEK 183 ++ E F K L + Sbjct: 59 SQTDSLEDEEIETFYKMLTQ 78 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 25/44 (56%) Query: 145 GVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQ 188 G ++L++ +++AD++ D ++F E L++++++ Sbjct: 1 GSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQV 44 >5LPU-C nrPDB Length = 104 Score = 29.7 bits (65), Expect = 0.75, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 22/49 (44%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 K+++ E+ ++L + + + E + + D + D V F E+ Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYC 79 >6FFL-A nrPDB Length = 388 Score = 29.7 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 38/122 (31%), Gaps = 17/122 (13%) Query: 24 SQASLLRLHHRFRALDRNKKG----YLSRMDLQQIGALA-----VNPLGDRIIESFFPDG 74 + L F++ G Y + + LG ++F P Sbjct: 38 TYRETEELRSSFQSAAMGGSGPELVYGPSDQVGPFATMGIVRPLDEVLGSDYFQNFDPLA 97 Query: 75 SQRVDFPGFV---RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 + D ++ V H + ++ T PK + L K+ D + DGKI Sbjct: 98 APVYDGKHYMIGDAVGNHLMLLYNKKFITTPPKNSQELIELGKKM-----TVDTNGDGKI 152 Query: 132 SR 133 R Sbjct: 153 DR 154 >1SRA-A nrPDB Length = 151 Score = 29.7 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 35/80 (43%), Gaps = 10/80 (12%) Query: 116 LHYAFQLYDLDR-DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 +H+ F D DG +S E+ + ++ +E+ R + D D D ++ Sbjct: 79 VHWQFGQLDQHPIDGYLSHTELAPLRAPLI-------PMEHCTTRFFETCDLDNDKYIAL 131 Query: 175 VEF--TKSLEKMDVEQKMSI 192 E+ +++ D+++ + I Sbjct: 132 DEWAGCFGIKQKDIDKDLVI 151 >5C5V-A nrPDB Length = 342 Score = 29.7 bits (65), Expect = 0.85, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG-DGA 171 + + F +D+ G ++ ++ +V R + G +++ ++ + +A+ + DG Sbjct: 6 KKIMSRLFSAFDVTHLGYLTPDKVEEVCRYL-GRNMSDGDVKAM------KAEINAIDGH 58 Query: 172 VSFVEF 177 V+F +F Sbjct: 59 VTFEKF 64 >2VTG-A nrPDB Length = 150 Score = 29.7 bits (65), Expect = 0.89, Method: Composition-based stats. Identities = 9/76 (11%), Positives = 28/76 (36%), Gaps = 5/76 (6%) Query: 106 PEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEAD 165 E L + + +DL+ +G+I + +++ ++ + + + E Sbjct: 42 EENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMM-----EKLGVPKTHLEMKKMISEVT 96 Query: 166 EDGDGAVSFVEFTKSL 181 +S+ +F + Sbjct: 97 GGVSDTISYRDFVNMM 112 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 26/70 (37%), Gaps = 4/70 (5%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQIGA-LAVNPL---GDRIIESFFPDGSQRVDFP 81 L ++ D N +G + M L+++ L V ++I S + + Sbjct: 47 EKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYR 106 Query: 82 GFVRVLAHFR 91 FV ++ R Sbjct: 107 DFVNMMLGKR 116 >4AOM-A nrPDB Length = 146 Score = 29.7 bits (65), Expect = 0.90, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 23/64 (35%), Gaps = 2/64 (3%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL-AVNPLGDRIIESFFPDGS-QRVDFP 81 + ++ L F D N GYL++ ++ I I++ S +D+ Sbjct: 79 DKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYK 138 Query: 82 GFVR 85 F Sbjct: 139 LFCE 142 Score = 29.3 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADED 167 +L F +D + G +++ +M +L G +T+++ + + E + D Sbjct: 84 EELIKMFAHFDNNCTGYLTKSQMKNILTT-WGDALTDQEAIDALNAFSSEDNID 136 >2AUC-A nrPDB Length = 126 Score = 29.7 bits (65), Expect = 0.94, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 29/66 (43%), Gaps = 7/66 (10%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 +L F +D + G +++++M +L G +TE++ + + E ++ Sbjct: 65 EELIKMFSHFDNNSSGFLTKNQMKNILTT-WGDALTEQEANDALNAFSSE------DRIN 117 Query: 174 FVEFTK 179 + F + Sbjct: 118 YKLFCE 123 >3BOW-B nrPDB Length = 184 Score = 29.3 bits (64), Expect = 0.98, Method: Composition-based stats. Identities = 27/193 (13%), Positives = 56/193 (29%), Gaps = 62/193 (32%) Query: 26 ASLLRLHHRFRALDRNKKGYLSRMDLQQI--------GALAVNPLG----DRIIESFFPD 73 + F L + +S +L I L + G ++ D Sbjct: 12 EEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 70 Query: 74 GSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 + ++ F F + L + K ++ +D DR G I Sbjct: 71 TTGKLGFEEF-----------------------KYLWNNIKKWQGIYKRFDTDRSGTIGS 107 Query: 134 HE-----------MLQVLRLMVGVQVTEEQLENIAD-------------RTVQEADEDGD 169 +E + Q + M+ + ++E D R + D++G Sbjct: 108 NELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGT 167 Query: 170 GAV--SFVEFTKS 180 G + + E+ + Sbjct: 168 GQIQVNIQEWLQL 180 >5CUY-A nrPDB Length = 414 Score = 29.3 bits (64), Expect = 0.99, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 33/66 (50%), Gaps = 8/66 (12%) Query: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG-DGA 171 + + F +D+ G ++ ++ +V R + G +++ ++ + +A+ + DG Sbjct: 78 KKIMSRLFSAFDVTHLGYLTPDKVEEVCRYL-GRNMSDGDVKAM------KAEINAIDGH 130 Query: 172 VSFVEF 177 V+F +F Sbjct: 131 VTFEKF 136 >4DUQ-A nrPDB Length = 98 Score = 29.3 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 24/48 (50%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 K+S+ EM ++L + V E+ E + + DE+ D V F E+ Sbjct: 29 KLSKGEMKELLHKELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEY 76 >4CFQ-A nrPDB Length = 91 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 22/49 (44%) Query: 130 KISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 K+++ E+ ++L + + + E + + D + D V F E+ Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYC 79 >2JQ6-A nrPDB Length = 139 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 19/50 (38%), Gaps = 7/50 (14%) Query: 128 DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +GKI+ + V + + + + AD D DG + EF Sbjct: 64 NGKITGANAKK-------EMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >5X2G-A nrPDB Length = 835 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 59/164 (35%), Gaps = 15/164 (9%) Query: 42 KKGYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQ 101 K G L+ +++ L+ + E G+ ++F + + + Sbjct: 306 KNGTLTYKQTKKLLGLSDD------YEFKGEKGTYFIEFKKYKEFIKALGEHNLSQDDLN 359 Query: 102 DPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEM---------LQVLRLMVGVQVTEEQ 152 + K L KL A YDL+++ S ++ + L+L+ + + ++ Sbjct: 360 EIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLMLEGKK 419 Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 + + + + D F ++ K +V + +R +K Sbjct: 420 YDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIK 463 >4GFT-A nrPDB Length = 69 Score = 28.9 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 23/64 (35%), Gaps = 2/64 (3%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL-AVNPLGDRIIESFFPDGS-QRVDFP 81 + ++ L F D N GYL++ ++ I I++ S +D+ Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYK 61 Query: 82 GFVR 85 F Sbjct: 62 LFCE 65 Score = 28.9 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 114 NKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADED 167 +L F +D + G +++ +M +L G +T+++ + + E + D Sbjct: 7 EELIKMFAHFDNNSTGYLTKSQMKNILTT-WGDALTDQEAIDALNAFSSEDNID 59 >2KFH-A nrPDB Length = 105 Score = 28.9 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 19/50 (38%), Gaps = 7/50 (14%) Query: 128 DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 +GKI+ + V + + + + AD D DG + EF Sbjct: 30 NGKITGANAKK-------EMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >2D58-A nrPDB Length = 107 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 11/93 (11%), Positives = 31/93 (33%), Gaps = 5/93 (5%) Query: 89 HFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQV 148 + + + E L S+ + +DL+ +G I + ++L ++ Sbjct: 7 RLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRML-----EKL 61 Query: 149 TEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 + + + E S+ +F + + Sbjct: 62 GVPKTHLELKKLIGEVSSGSGETFSYPDFLRMM 94 Score = 27.0 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 27/70 (38%), Gaps = 4/70 (5%) Query: 26 ASLLRLHHRFRALDRNKKGYLS----RMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFP 81 + L ++ D N G + + L+++G + ++I + +P Sbjct: 29 SKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYP 88 Query: 82 GFVRVLAHFR 91 F+R++ R Sbjct: 89 DFLRMMLGKR 98 >1L9X-A nrPDB Length = 315 Score = 28.5 bits (62), Expect = 1.7, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 15/54 (27%) Query: 80 FPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISR 133 F F L VE + KL F + + DGKI Sbjct: 171 FQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGKIEF 224 >2KHN-A nrPDB Length = 121 Score = 28.5 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 20/39 (51%) Query: 153 LENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVEQKMS 191 + + + AD + DG + VEF+ +++ + ++ + Sbjct: 64 PQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGY 102 >5ES6-A nrPDB Length = 685 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 42/119 (35%), Gaps = 13/119 (10%) Query: 9 AVIPDGDSIRRETGFSQASLLRLH------HRFRALDRNKKGYLSRMDLQQIGALAVNPL 62 A IP G I R L L F + +GYL+R +L + Sbjct: 500 ANIPIGKPIDRTRILILDEALALQPIGVAGELFIVGEGLGRGYLNRPELTAEKFIVHPQT 559 Query: 63 GDRIIES-----FFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKL 116 G+R+ + F PDG+ ++F G + L R E E + PL L Sbjct: 560 GERMYRTGDRARFLPDGN--IEFLGRLDNLVKIRGYRIEPGEIEPFLMNHPLIELTTVL 616 >5ZCR-A nrPDB Length = 728 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 32/88 (36%) Query: 67 IESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLD 126 I+ F + S R DF F + + +F ++ T P + + + F L D D Sbjct: 553 IDEVFENSSFRNDFDNFEKKIVYFGYMKSLVATTLKFLSPGVPDIYQGTEVWRFLLTDPD 612 Query: 127 RDGKISRHEMLQVLRLMVGVQVTEEQLE 154 + ++ ++L + + Sbjct: 613 NRMAVDFRKLRELLNNLTEKNLELSDPR 640 >2JTT-A nrPDB Length = 90 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 27/50 (54%), Gaps = 6/50 (12%) Query: 131 ISRHEMLQVLRL--MVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFT 178 +S+ E+ ++++ +G ++ + ++ + D + D + D V+F E+ Sbjct: 29 LSKKELKELIQKELTIGSKLQDAEIVKLMD----DLDRNKDQEVNFQEYI 74 >4DKN-A nrPDB Length = 223 Score = 28.1 bits (61), Expect = 2.3, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 47/138 (34%), Gaps = 17/138 (12%) Query: 44 GYLSRMDLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDP 103 G ++ + +G +P ++ + + F ++ ++ H + D Sbjct: 17 GSINGHEFDMVGGGKGDPNAGSLVTTAKST-KGALKFSPYL-MIPHLGYGYYQYLPYPDG 74 Query: 104 KKPEPLNSRRNKLHYAFQLYDLDRDGKISRH--------EMLQVLRLMVGVQVTEEQLEN 155 P ++ + ++++D + GK+S + ++LM + + Sbjct: 75 PSPFQVSMLEGSGYAVYRVFDFEDGGKLSTEFKYSYEGSHIKADMKLMGSGFPDDGPV-- 132 Query: 156 IADRTVQEADEDGDGAVS 173 + D DG VS Sbjct: 133 ----MTSQI-VDQDGCVS 145 >5ES8-A nrPDB Length = 776 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 42/119 (35%), Gaps = 13/119 (10%) Query: 9 AVIPDGDSIRRETGFSQASLLRLH------HRFRALDRNKKGYLSRMDLQQIGALAVNPL 62 A IP G I R L L F + +GYL+R +L + Sbjct: 500 ANIPIGKPIDRTRILILDEALALQPIGVAGELFIVGEGLGRGYLNRPELTAEKFIVHPQT 559 Query: 63 GDRIIES-----FFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKL 116 G+R+ + F PDG+ ++F G + L R E E + PL L Sbjct: 560 GERMYRTGDRARFLPDGN--IEFLGRLDNLVKIRGYRIEPGEIEPFLMNHPLIELTTVL 616 >5MVF-A nrPDB Length = 523 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 9/63 (14%) Query: 128 DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMDVE 187 +GKIS VT + ++ + + AD D DG + EF +L K ++ Sbjct: 444 NGKISG-------VNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEF--ALAKHLIK 494 Query: 188 QKM 190 K+ Sbjct: 495 IKL 497 >1SNL-A nrPDB Length = 103 Score = 27.8 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 31/77 (40%), Gaps = 11/77 (14%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLEN-----------IADRTVQEADEDG 168 F L+D++ DG + E+ + + + E+ + + ++ D + Sbjct: 26 FILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQ 85 Query: 169 DGAVSFVEFTKSLEKMD 185 D V+ EF S ++ + Sbjct: 86 DRLVTLEEFLASTQRKE 102 >3VSL-A nrPDB Length = 646 Score = 27.8 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 15/29 (51%), Gaps = 2/29 (6%) Query: 24 SQASLLRLHHRFRAL--DRNKKGYLSRMD 50 ++ + ++ F+ D++ GY+S D Sbjct: 537 TEKEIKQIQEGFKMAFNDKDGTGYVSFKD 565 >2JMM-A nrPDB Length = 156 Score = 27.8 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 6/12 (50%), Positives = 7/12 (58%) Query: 124 DLDRDGKISRHE 135 D D +G IS E Sbjct: 90 DKDGNGYISAAE 101 >4JB3-A nrPDB Length = 228 Score = 27.8 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 20/44 (45%) Query: 122 LYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEAD 165 ++ +GK+S E + L + G ++T E+ + E D Sbjct: 67 IFQELEEGKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNEVD 110 >5CUU-A nrPDB Length = 414 Score = 27.4 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 32/74 (43%), Gaps = 6/74 (8%) Query: 104 KKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQE 163 K L+ + + F +D+ + G + ++ + + + G + E+ ++ + + Sbjct: 68 KDEFTLSMEKRVMARMFSAFDVTQLGYLEERKIEHMCKYL-GRVMNEDDVKQMKSE-INA 125 Query: 164 ADEDGDGAVSFVEF 177 D G ++F +F Sbjct: 126 ID----GHITFEKF 135 >1C07-A nrPDB Length = 95 Score = 27.4 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 28/88 (31%), Gaps = 2/88 (2%) Query: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNP--LGDRIIESFFPDGSQRVDFP 81 S A + F D++ G++S +++++I P L I ++ Sbjct: 5 SPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKD 64 Query: 82 GFVRVLAHFRPVEDEDTETQDPKKPEPL 109 F + + PE + Sbjct: 65 QFALAFHLISQKLIKGIDPPHVLTPEMI 92 >4K00-A nrPDB Length = 141 Score = 27.4 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 11/20 (55%) Query: 164 ADEDGDGAVSFVEFTKSLEK 183 AD DG G V F +F + + Sbjct: 16 ADTDGAGVVYFNQFLQMCHE 35 >4PCW-A nrPDB Length = 94 Score = 27.4 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 15/37 (40%) Query: 148 VTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKM 184 + ++ D + D D + + F EF + K+ Sbjct: 47 LKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFKL 83 >5NRM-B nrPDB Length = 66 Score = 27.0 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 124 DLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKS 180 D+D +G I+ + ++R + + + E+ ++ D +GD +++ +F Sbjct: 4 DVDGNGSINSID-FALMRNYLLGNLKDFPAEDD----IKAGDLNGDKSININDFAIM 55 >2XU0-A nrPDB Length = 487 Score = 27.0 bits (58), Expect = 5.5, Method: Composition-based stats. Identities = 9/62 (14%), Positives = 21/62 (33%), Gaps = 2/62 (3%) Query: 50 DLQQIGALAVNPLGDRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPL 109 ++Q+ N E+ +D F+ +L + + D E +P+ Sbjct: 401 EIQKWKKTKNNYYDKEFYENLDKKSYSTID--KFLNLLNNGKHCHDNKDEKNKIDFNKPI 458 Query: 110 NS 111 + Sbjct: 459 KT 460 >5ED8-A nrPDB Length = 268 Score = 27.0 bits (58), Expect = 5.9, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 21/42 (50%) Query: 133 RHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSF 174 + Q+L+ V VTEEQ+ I + +Q ED G V + Sbjct: 59 AASLGQILQKEGIVGVTEEQVHRIVKQALQRYSEDRIGMVDY 100 >4CJ1-A nrPDB Length = 625 Score = 26.6 bits (57), Expect = 6.7, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 24/50 (48%), Gaps = 5/50 (10%) Query: 124 DLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVS 173 D++ DGK++ ++ + R ++ T + + AD + DG V+ Sbjct: 561 DVNDDGKVNSTDLTLLKRYVLKAVSTLPSSKAE-----KNADVNRDGRVN 605 >4EAC-A nrPDB Length = 414 Score = 26.6 bits (57), Expect = 7.4, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 29/92 (31%), Gaps = 2/92 (2%) Query: 19 RETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGALAVNPLGDRIIE--SFFPDGSQ 76 E +++ + + RF + K L+R + + D+ + + D + Sbjct: 166 AEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDK 225 Query: 77 RVDFPGFVRVLAHFRPVEDEDTETQDPKKPEP 108 F L PV +E +P Sbjct: 226 AKLRENFAVFLKAIIPVAEEVGVRMAVHPDDP 257 >5KU1-A nrPDB Length = 424 Score = 26.2 bits (56), Expect = 8.8, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDG--DGAVSFVEF 177 F++ D D DG ++ E+ + + Q V++ DG D ++ F Sbjct: 17 FKISDQDNDGTLNDAEL-NFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGF 75 Query: 178 T 178 Sbjct: 76 L 76 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.130 0.338 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,304,582 Number of Sequences: 36641 Number of extensions: 259680 Number of successful extensions: 3747 Number of sequences better than 10.0: 339 Number of HSP's better than 10.0 without gapping: 406 Number of HSP's successfully gapped in prelim test: 113 Number of HSP's that attempted gapping in prelim test: 1132 Number of HSP's gapped (non-prelim): 1213 length of query: 196 length of database: 10,336,785 effective HSP length: 92 effective length of query: 104 effective length of database: 6,965,813 effective search space: 724444552 effective search space used: 724444552 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 56 (26.2 bits)