BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O43252 (624 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1X6V-B nrPDB 1304 0.0 2QJF-A nrPDB 851 0.0 4MAF-A nrPDB 490 e-139 2OFX-A nrPDB 424 e-119 2PEY-A nrPDB 369 e-102 2AX4-A nrPDB 353 9e-98 6C6B-A nrPDB 220 2e-57 1M7G-A nrPDB 216 3e-56 3CR7-A nrPDB 203 1e-52 3UIE-A nrPDB 188 5e-48 4BZX-A nrPDB 186 2e-47 5CB6-A nrPDB 167 2e-41 2GKS-A nrPDB 149 2e-36 2YVU-A nrPDB 149 3e-36 4DNX-A nrPDB 142 4e-34 3CR8-A nrPDB 137 1e-32 1JHD-A nrPDB 130 1e-30 1I2D-A nrPDB 129 3e-30 1V47-A nrPDB 123 3e-28 1J70-A nrPDB 122 7e-28 1R6X-A nrPDB 121 1e-27 3NHB-A nrPDB 33 0.38 5L3R-A nrPDB 33 0.43 2I3B-A nrPDB 32 0.63 3A4L-A nrPDB 32 0.64 2P5T-B nrPDB 32 0.84 3E70-C nrPDB 32 0.92 3TCQ-A nrPDB 32 1.1 3KFL-A nrPDB 32 1.1 2G77-B nrPDB 31 1.3 1Z06-A nrPDB 31 1.4 4AYX-A nrPDB 30 2.3 4QIW-C nrPDB 30 2.6 6BBQ-A nrPDB 30 3.1 4EUN-A nrPDB 29 5.1 5HJR-A nrPDB 29 6.1 5XF8-3 nrPDB 29 6.2 1WDT-A nrPDB 29 6.2 2F6K-A nrPDB 29 7.2 4OI0-A nrPDB 29 7.2 3BZN-A nrPDB 28 8.2 >1X6V-B nrPDB Length = 630 Score = 1304 bits (3375), Expect = 0.0, Method: Compositional matrix adjust. Identities = 623/624 (99%), Positives = 623/624 (99%) Query: 1 MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL 60 MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL Sbjct: 1 MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL 60 Query: 61 SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF 120 SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF Sbjct: 61 SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF 120 Query: 121 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG 180 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG Sbjct: 121 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG 180 Query: 181 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP 240 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP Sbjct: 181 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP 240 Query: 241 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG Sbjct: 241 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300 Query: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC 360 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC Sbjct: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC 360 Query: 361 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL 420 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAV AFQL Sbjct: 361 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVSAFQL 420 Query: 421 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV 480 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV Sbjct: 421 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV 480 Query: 481 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS 540 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS Sbjct: 481 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS 540 Query: 541 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK 600 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK Sbjct: 541 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK 600 Query: 601 PPEGFMAPKAWTVLTEYYKSLEKA 624 PPEGFMAPKAWTVLTEYYKSLEKA Sbjct: 601 PPEGFMAPKAWTVLTEYYKSLEKA 624 >2QJF-A nrPDB Length = 405 Score = 851 bits (2198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/405 (100%), Positives = 405/405 (100%) Query: 220 LQERDIVPVDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLN 279 LQERDIVPVDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLN Sbjct: 1 LQERDIVPVDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLN 60 Query: 280 GFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILR 339 GFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILR Sbjct: 61 GFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILR 120 Query: 340 NPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLT 399 NPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLT Sbjct: 121 NPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLT 180 Query: 400 PTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTK 459 PTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTK Sbjct: 181 PTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTK 240 Query: 460 DDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYI 519 DDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYI Sbjct: 241 DDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYI 300 Query: 520 VGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEH 579 VGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEH Sbjct: 301 VGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEH 360 Query: 580 HEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA 624 HEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA Sbjct: 361 HEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA 405 >4MAF-A nrPDB Length = 404 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 236/390 (60%), Positives = 292/390 (74%), Gaps = 4/390 (1%) Query: 236 ELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDC 295 EL V + + L K +A +LP +K++++D++WV VL+EGWATPL GFMRE E+LQ LHF+ Sbjct: 12 ELVVTDFERDLKKGEALSLPRIKLSRIDLEWVHVLSEGWATPLKGFMREAEFLQTLHFNS 71 Query: 296 LL--DGGVINLSVPIVLTATHEDKERLDGCTAFALM-YEGRRVAILRNPEFFEHRKEERC 352 L DG V+N+SVPIVL K R+ AL +G VAIL N E ++H KEER Sbjct: 72 LRLDDGSVVNMSVPIVLAIDDAQKHRIGDNKKVALFDSKGDPVAILNNIEIYKHPKEERI 131 Query: 353 ARQWGTTCKNHPYI-KMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMN 411 AR WGT PY+ + + G+WLIGGDL+V++ + +NDGLD +RL+PT+L+ +F N Sbjct: 132 ARTWGTIAPGLPYVEQTITNAGNWLIGGDLEVIEPIQYNDGLDHFRLSPTQLRAEFTRRN 191 Query: 412 ADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQ 471 ADAVFAFQLRNPVHNGHALLM DT K+LLE GY+ PVLLLHPLGG+TK DDVPL WRMKQ Sbjct: 192 ADAVFAFQLRNPVHNGHALLMTDTRKRLLEMGYKNPVLLLHPLGGYTKADDVPLDWRMKQ 251 Query: 472 HAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPE 531 H VLE+GVL+PETTVV+IFPSPM YAGPTEVQWH +AR+ AGANFYIVGRDPAGM HP Sbjct: 252 HEKVLEDGVLDPETTVVSIFPSPMHYAGPTEVQWHAKARINAGANFYIVGRDPAGMSHPV 311 Query: 532 TGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRM 591 +DLY+ HG KVL+MAPGL L I+PFRVAAY+K + +M ++D +DF FISGT+M Sbjct: 312 EKRDLYDADHGKKVLSMAPGLERLNILPFRVAAYDKTQGKMAFFDPSRPQDFLFISGTKM 371 Query: 592 RKLAREGQKPPEGFMAPKAWTVLTEYYKSL 621 R LAR + PP+GFM P W VL +YY SL Sbjct: 372 RTLARNKESPPDGFMCPGGWKVLVDYYDSL 401 >2OFX-A nrPDB Length = 207 Score = 424 bits (1091), Expect = e-119, Method: Compositional matrix adjust. Identities = 203/203 (100%), Positives = 203/203 (100%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 84 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY Sbjct: 5 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 64 Query: 85 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 144 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ Sbjct: 65 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 124 Query: 145 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKT 204 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKT Sbjct: 125 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKT 184 Query: 205 DSCDVNDCVQQVVELLQERDIVP 227 DSCDVNDCVQQVVELLQERDIVP Sbjct: 185 DSCDVNDCVQQVVELLQERDIVP 207 >2PEY-A nrPDB Length = 179 Score = 369 bits (946), Expect = e-102, Method: Compositional matrix adjust. Identities = 177/179 (98%), Positives = 177/179 (98%) Query: 48 GGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDRE 107 G RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDRE Sbjct: 1 GHMRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDRE 60 Query: 108 ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQ 167 ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQ Sbjct: 61 ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQ 120 Query: 168 RDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 226 RDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV Sbjct: 121 RDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 179 >2AX4-A nrPDB Length = 198 Score = 353 bits (907), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 164/197 (83%), Positives = 181/197 (91%) Query: 31 QAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDN 90 QAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTT+S ALEEYLV H IPCY+LDGDN Sbjct: 1 QAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDN 60 Query: 91 IRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGAS 150 +R GLN+NLGFSP DREEN+RRIAEVAKLFADAGLVCITSFISP+ +DR NAR+IHE A Sbjct: 61 VRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAG 120 Query: 151 LPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVN 210 LPFFE+FVDAPL++CE RDVKGLYK+ARAGEIKGFTGIDS+YEKPE PE VLKT+ V+ Sbjct: 121 LPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVS 180 Query: 211 DCVQQVVELLQERDIVP 227 DCV QVVELLQE++IVP Sbjct: 181 DCVHQVVELLQEQNIVP 197 >6C6B-A nrPDB Length = 211 Score = 220 bits (560), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 105/205 (51%), Positives = 145/205 (70%), Gaps = 6/205 (2%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 84 ATN+T+ V++++R ++G +G CTVWLTGLS +GK+T++ ALE++L+ + Y Sbjct: 10 ATNITFHPGAVTQDERDTLLGQKG----CTVWLTGLSASGKSTIATALEQHLLHKKLHAY 65 Query: 85 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 144 LDGDNIR GLNK+LGF R EN+RRI EV+ LFA + + +T+FISPY DR AR+ Sbjct: 66 RLDGDNIRFGLNKDLGFDQASRVENIRRIGEVSLLFALSSTISVTAFISPYISDRQLARE 125 Query: 145 IHE--GASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVL 202 +HE +++PF EVF+DAPL V EQRD KGLYKKARAGEIK FTGI + YE P PE+ + Sbjct: 126 LHEKHSSAIPFIEVFIDAPLSVVEQRDPKGLYKKARAGEIKDFTGISAPYEAPANPEIHI 185 Query: 203 KTDSCDVNDCVQQVVELLQERDIVP 227 +TD DV V+ + + L + ++P Sbjct: 186 RTDEVDVAGAVEIITKYLADNGLIP 210 >1M7G-A nrPDB Length = 211 Score = 216 bits (549), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 110/210 (52%), Positives = 145/210 (69%), Gaps = 11/210 (5%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVC-HGIPC 83 +TN+T+ A ++R++R ++ RG T+WLTGLS +GK+T+++ LE LV + Sbjct: 2 STNITFHASALTRSERTELRNQRG----LTIWLTGLSASGKSTLAVELEHQLVRDRRVHA 57 Query: 84 YTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNAR 143 Y LDGDNIR GLNK+LGFS DR EN+RRIAEVAKLFAD+ + ITSFISPY +DR+ AR Sbjct: 58 YRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTAR 117 Query: 144 QIHEGAS------LPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEA 197 Q+HE A+ LPF EV+VD P+ V EQRD KGLYKKAR G IK FTGI + YE P Sbjct: 118 QLHEVATPGEETGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPAN 177 Query: 198 PELVLKTDSCDVNDCVQQVVELLQERDIVP 227 PE+ +K V D V+Q+++ L + +P Sbjct: 178 PEVHVKNYELPVQDAVKQIIDYLDTKGYLP 207 >3CR7-A nrPDB Length = 197 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 105/190 (55%), Positives = 131/190 (68%), Gaps = 7/190 (3%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVC-HGIPCYTLDGDNIRQGLNKNLGFSPEDREEN 109 RG T+WLTGLS +GK+T+++ LE LV + Y LDGDNIR GLNK+LGFS DR EN Sbjct: 2 RGLTIWLTGLSASGKSTLAVELEHQLVRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNEN 61 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGAS------LPFFEVFVDAPLH 163 +RRIAEVAKLFAD+ + ITSFISPY +DR+ ARQ+HE A+ LPF EV+VD P+ Sbjct: 62 IRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEVATPGEETGLPFVEVYVDVPVE 121 Query: 164 VCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER 223 V EQRD KGLYKKAR G IK FTGI + YE P PE+ +K V D V+Q+++ L + Sbjct: 122 VAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTK 181 Query: 224 DIVPVDASYE 233 +P E Sbjct: 182 GYLPAKKELE 191 >3UIE-A nrPDB Length = 200 Score = 188 bits (478), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 95/181 (52%), Positives = 122/181 (67%), Gaps = 12/181 (6%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 84 +TN+ + V + R +++ +G C +W+TGLSG+GK+T++ AL + L G CY Sbjct: 2 STNIKWHECSVEKVDRQRLLDQKG----CVIWVTGLSGSGKSTLACALNQMLYQKGKLCY 57 Query: 85 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 144 LDGDN+R GLN++L F EDR EN+RR+ EVAKLFADAG++CI S ISPY DR+ R Sbjct: 58 ILDGDNVRHGLNRDLSFKAEDRAENIRRVGEVAKLFADAGIICIASLISPYRTDRDACRS 117 Query: 145 IHEGASLP---FFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELV 201 + LP F EVF+D PL VCE RD KGLYK ARAG+IKGFTGID YE P E+ Sbjct: 118 L-----LPEGDFVEVFMDVPLSVCEARDPKGLYKLARAGKIKGFTGIDDPYEPPLNCEIS 172 Query: 202 L 202 L Sbjct: 173 L 173 >4BZX-A nrPDB Length = 173 Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 91/172 (52%), Positives = 120/172 (69%), Gaps = 1/172 (0%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENV 110 RG TVW TGLSG+GK++V+M +E L+ GI Y LDGDN+R GLN +LGFS DR EN+ Sbjct: 3 RGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENL 62 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDV 170 RR++ VA L AD G + + ISP + R AR++H A + FFEVF D PL CE+RD Sbjct: 63 RRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDP 122 Query: 171 KGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQE 222 KGLY KARAGEI FTGIDS Y++P+ P+L L D +++ Q+V++LL+ Sbjct: 123 KGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDRS-IDEQAQEVIDLLES 173 >5CB6-A nrPDB Length = 197 Score = 167 bits (422), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 85/166 (51%), Positives = 109/166 (65%), Gaps = 4/166 (2%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENV 110 RG T+WLTGLSGAGKTT++ ALE+ L G LDGD +R L K LGFS EDR+ N+ Sbjct: 24 RGVTIWLTGLSGAGKTTITHALEKKLRDSGYRLEVLDGDVVRTNLTKGLGFSKEDRDTNI 83 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDV 170 RRI V+ L G++ + S ISPY R + F EVFV+APL VCE+RDV Sbjct: 84 RRIGFVSHLLTRNGVIVLVSAISPYAAIRQEVKH----TIGDFLEVFVNAPLAVCEERDV 139 Query: 171 KGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQV 216 KGLY KAR+GEIKGFTGID YE P P++ +TD ++++ V ++ Sbjct: 140 KGLYAKARSGEIKGFTGIDDPYEPPTNPDVECRTDLEELDESVGKI 185 >2GKS-A nrPDB Length = 546 Score = 149 bits (377), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 78/176 (44%), Positives = 103/176 (58%), Gaps = 2/176 (1%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENV 110 +G VWLTGL AGK+T++ L L G LDGD +R L++ LGFS EDR N+ Sbjct: 371 QGFCVWLTGLPCAGKSTIAEILATMLQARGRKVTLLDGDVVRTHLSRGLGFSKEDRITNI 430 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDV 170 R+ VA V I + +SPY RN R + E F EVFVDAP+ VCE+RDV Sbjct: 431 LRVGFVASEIVKHNGVVICALVSPYRSARNQVRNMMEEGK--FIEVFVDAPVEVCEERDV 488 Query: 171 KGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 226 KGLYKKA+ G IKGFTG+D YE P APE+ + T + +++E L++ + Sbjct: 489 KGLYKKAKEGLIKGFTGVDDPYEPPVAPEVRVDTTKLTPEESALKILEFLKKEGFI 544 Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 114/379 (30%), Positives = 179/379 (47%), Gaps = 34/379 (8%) Query: 254 LPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTAT 313 L +++I++ + +++LA G TPL+ FM E +Y + L G + +PI L Sbjct: 7 LKSIQISQRSVLDLELLAVGAFTPLDRFMGEEDYRNVVESMRLKSGTL--FPIPITLPME 64 Query: 314 HEDKERLDGCTAFALM-YEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQ 372 E + L L + +AI+R E ++ E GTT HP + + Sbjct: 65 KEIAKDLKEGEWIVLRDPKNVPLAIMRVEEVYKWNLEYEAKNVLGTTDPRHPLVAEMHTW 124 Query: 373 GDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLM 432 G++ I G+L+V+ + D +YR TP +++++ K + D + AFQ RNP+H Sbjct: 125 GEYYISGELKVIQLPKYYD-FPEYRKTPKQVREEIKSLGLDKIVAFQTRNPMHR------ 177 Query: 433 QDTHKQLLERGYRRPV--LLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVVAI 490 H++L +R + LLLHP+ G TK DV + RM+ + VL E + + T++A Sbjct: 178 --VHEELTKRAMEKVGGGLLLHPVVGLTKPGDVDVYTRMRIYK-VLYEKYYDKKKTILAF 234 Query: 491 FPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAP 550 P M AGP E WH R GA +IVGRD A GK Y+P ++ Sbjct: 235 LPLAMRMAGPREALWHGIIRRNYGATHFIVGRDHASPGKDSKGKPFYDPYEAQELFKKYE 294 Query: 551 GLITLEIVPFRVAAY----------NKKKKRMDYYDSEHHEDFEFISGTRMRK-LAREGQ 599 I +++VPF Y N+ KKR Y + ISGT +R+ ++G+ Sbjct: 295 DEIGIKMVPFEELVYVPELDQYVEINEAKKRNLKYIN--------ISGTEIRENFLKQGR 346 Query: 600 KPPEGFMAPKAWTVLTEYY 618 K PE F P+ +L E Y Sbjct: 347 KLPEWFTRPEVAEILAETY 365 >2YVU-A nrPDB Length = 186 Score = 149 bits (377), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 76/171 (44%), Positives = 107/171 (62%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENV 110 +G VWLTGL G+GKTT++ L + L G LDGD R +++ GF+ E+R ++ Sbjct: 12 KGIVVWLTGLPGSGKTTIATRLADLLQKEGYRVEVLDGDWARTTVSEGAGFTREERLRHL 71 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDV 170 +RIA +A+L A G++ I SF+SPY Q RN R+I E +PF E++V A L +RD Sbjct: 72 KRIAWIARLLARNGVIVICSFVSPYKQARNMVRRIVEEEGIPFLEIYVKASLEEVIRRDP 131 Query: 171 KGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQ 221 KGLYKKA GE++ FTGI YE PE P+LVL T+S + V + L++ Sbjct: 132 KGLYKKALKGELENFTGITDPYEPPENPQLVLDTESNTIEHNVSYLYSLVK 182 >4DNX-A nrPDB Length = 397 Score = 142 bits (358), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 119/403 (29%), Positives = 187/403 (46%), Gaps = 35/403 (8%) Query: 237 LYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCL 296 +Y PE H ++AE+LP++ ++ +L G+ +PL+GFM + L L Sbjct: 15 VYDPEQH-HRLSSEAESLPSVIVSSQAAGNAVMLGAGYFSPLDGFMNLADALSSAQSMTL 73 Query: 297 LDGGVINLSVPIVLTATHEDKERLDGCTAFALM---YEGRRVAILRNPEFFEHRKEERCA 353 DG P+ L E + + G T AL EG V + + E + + A Sbjct: 74 TDGRFF----PVPLLCLLESADAIAGATRIALRDPNVEGNPVLAVMDVTAVEQVSDAQMA 129 Query: 354 ----RQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYW-NDGLDQYRLTPTELKQKFK 408 + +GT+ HP ++ QG I G +QVL+ Y+ D D +R T E++ + + Sbjct: 130 LMTEQVYGTSDPKHPGVETFNSQGRTAISGPIQVLNFSYFQTDFPDTFR-TAVEIRHEIQ 188 Query: 409 DMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWR 468 + + AFQ RNP+H H L + + + G +++H L G K D+P R Sbjct: 189 ERGWQKIVAFQTRNPMHRAHEELCKMAMEAVEADG-----VVIHMLLGQLKPGDIPAPVR 243 Query: 469 MKQHAAV--LEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAG 526 AA+ + E P T +V + M+YAGP E H R GA +I+GRD AG Sbjct: 244 ---DAAIRTMAELYFPPNTVMVTGYGFDMLYAGPREAVLHAYFRQNMGATHFIIGRDHAG 300 Query: 527 MPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRV--AAYNKKKKRMDYY-DSEHH--E 581 + D Y P + A L I FR AY+KK R+ D+ H + Sbjct: 301 V------GDYYGPFDAQTIFDDAVPTDVLAIEIFRADNTAYSKKLGRVVMMRDAPDHTPD 354 Query: 582 DFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA 624 DF +SGTR+R++ +G+ PP F P+ +L +YY+SL ++ Sbjct: 355 DFIQLSGTRVREMLGQGEAPPPEFSRPEVAQILMDYYRSLPQS 397 >3CR8-A nrPDB Length = 552 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 76/168 (45%), Positives = 100/168 (59%), Gaps = 2/168 (1%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL-DGDNIRQGLNKNLGFSPEDREEN 109 +G TV+ TGLSGAGK+T++ AL L+ G C TL DGD +R+ L+ LGFS R+ N Sbjct: 368 QGFTVFFTGLSGAGKSTLARALAARLMEMGGRCVTLLDGDIVRRHLSSELGFSKAHRDVN 427 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRD 169 VRRI VA + I + I+PY Q R + R + E F E+ V P+ CE RD Sbjct: 428 VRRIGFVASEITKNRGIAICAPIAPYRQTRRDVRAMIEAVG-GFVEIHVATPIETCESRD 486 Query: 170 VKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVV 217 KGLY KARAG I FTG+ YE PE PEL + T +++ VQQ++ Sbjct: 487 RKGLYAKARAGLIPEFTGVSDPYEVPETPELAIDTTGLAIDEAVQQIL 534 Score = 33.1 bits (74), Expect = 0.36, Method: Compositional matrix adjust. Identities = 94/407 (23%), Positives = 148/407 (36%), Gaps = 86/407 (21%) Query: 237 LYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCL 296 L PE + L K +A +LP+L ++ +++L G +PL GFM QC + Sbjct: 16 LIDPEKREAL-KHEALSLPSLDLDWQQQCELEMLMTGAYSPLTGFMTR---AQCARVESA 71 Query: 297 --LDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCAR 354 LD G S PI LT+ R+ + R ER A Sbjct: 72 QQLDDGSFWPS-PITLTS--------------------------RDRALADRRPGERLAL 104 Query: 355 QWGTTCKNHPYIKMVMEQGD-------WLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKF 407 + G Y+ ++ D W + G+++ D + R TP EL+ F Sbjct: 105 RDGEG-----YMLAILTLSDVWKDGERWHLAGEVEGAALPPHPDFVS-LRATPAELRALF 158 Query: 408 KDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMW 467 + A+Q R P+H + K +E LLLHP G + Sbjct: 159 VRRGWRRIIAWQARQPMHRAQ---YEFCLKSAIENEAN---LLLHPQVGGDITEAPAYFG 212 Query: 468 RMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGM 527 ++ A+ + TT +++ P+P A + G + I G G Sbjct: 213 LVRSFLAIRDR--FPAATTQLSLLPAPPPEASGRALLLRAIVARNFGCSLLIAG----GE 266 Query: 528 PHPE-----TGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYD--SEHH 580 P+ G+DL + V A E + R+ AY RM Y + +EH Sbjct: 267 HQPDGGDCRRGEDLTQNRVDPSVAERA------EKIGVRLIAY----PRMVYVEDRAEHL 316 Query: 581 EDFEFISGTRMRKLA--------REGQKPPEGFMAPKAWTVLTEYYK 619 + E G R+ L+ R G K PE + P+ VL E ++ Sbjct: 317 PEAEAPQGARLLTLSGEEFQRRMRAGLKIPEWYSFPE---VLAELHR 360 >1JHD-A nrPDB Length = 396 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 122/414 (29%), Positives = 189/414 (45%), Gaps = 38/414 (9%) Query: 225 IVPVDASYEVKELYV--PENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFM 282 I PV S E+K L+V PE H +AE+LP++ I+ ++ G+ +PL GFM Sbjct: 2 IKPV-GSDELKPLFVYDPEEH-HKLSHEAESLPSVVISSQAAGNAVMMGAGYFSPLQGFM 59 Query: 283 REREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALM---YEGRRVAILR 339 + + L DG P+ + E+ + + AL EG V + Sbjct: 60 NVADAMGAAEKMTLSDGSFF----PVPVLCLLENTDAIGDAKRIALRDPNVEGNPVLAVM 115 Query: 340 NPEFFEHRKEERCA----RQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWN-DGLD 394 + E E +E+ A + + TT +H +K QG + G +QVL+ Y+ D D Sbjct: 116 DIEAIEEVSDEQMAVMTDKVYRTTDMDHIGVKTFNSQGRVAVSGPIQVLNFSYFQADFPD 175 Query: 395 QYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPL 454 +R T E++ + K+ V AFQ RNP+H H L + + L G +++H L Sbjct: 176 TFR-TAVEIRNEIKEHGWSKVVAFQTRNPMHRAHEELCRMAMESLDADG-----VVVHML 229 Query: 455 GGWTKDDDVPLMWRMKQHAAV--LEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMV 512 G K D+P R AA+ + E P T +V + M+YAGP E H R Sbjct: 230 LGKLKKGDIPAPVR---DAAIRTMAEVYFPPNTVMVTGYGFDMLYAGPREAVLHAYFRQN 286 Query: 513 AGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLT--MAPGLITLEIVPFRVAAYNKK-K 569 GA +I+GRD AG+ D Y + + G + +EI AY+KK Sbjct: 287 MGATHFIIGRDHAGV------GDYYGAFDAQTIFDDEVPEGAMEIEIFRADHTAYSKKLN 340 Query: 570 KRMDYYDSEHH--EDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSL 621 K + D H EDF +SGT++R++ +G PP F P+ +L +YY+S+ Sbjct: 341 KIVMMRDVPDHTKEDFVLLSGTKVREMLGQGIAPPPEFSRPEVAKILMDYYQSI 394 >1I2D-A nrPDB Length = 573 Score = 129 bits (325), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 101/373 (27%), Positives = 168/373 (45%), Gaps = 16/373 (4%) Query: 249 TDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPI 308 +AE+LPA+ + + + ++++ G +PL GFM + +Y + + L DG V S+PI Sbjct: 26 AEAESLPAVTLTERQLCDLELIMNGGFSPLEGFMNQADYDRVCEDNRLADGNV--FSMPI 83 Query: 309 VLTATHE--DKERLDGCTAFAL--MYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHP 364 L A+ E D+++L + L + R +AIL + + K + +G ++ Sbjct: 84 TLDASQEVIDEKKLQAGSRITLRDFRDDRNLAILTIDDIYRPDKTKEAKLVFGGDPEHPA 143 Query: 365 YIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPV 424 + + ++ IGG ++ ++++ D + R TP EL+ F + V AFQ RNP+ Sbjct: 144 IVYLNNTVKEFYIGGKIEAVNKLNHYDYV-ALRYTPAELRVHFDKLGWSRVVAFQTRNPM 202 Query: 425 HNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPE 484 H H L + R+ +L+HP+ G TK D+ R++ + A+L Sbjct: 203 HRAHRELTVRAARS------RQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPR--YPNG 254 Query: 485 TTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAK 544 V+ + M GP E WH R GA +IVGRD AG G+D Y P Sbjct: 255 MAVLGLLGLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGSNSKGEDFYGPYDAQH 314 Query: 545 VLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEF-ISGTRMRKLAREGQKPPE 603 + + +E+V F++ Y D ISGT +R+ R G PE Sbjct: 315 AVEKYKDELGIEVVEFQMVTYLPDTDEYRPVDQVPAGVKTLNISGTELRRRLRSGAHIPE 374 Query: 604 GFMAPKAWTVLTE 616 F P+ +L E Sbjct: 375 WFSYPEVVKILRE 387 Score = 110 bits (274), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 70/174 (40%), Positives = 97/174 (55%), Gaps = 2/174 (1%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLD-GDNIRQGLNKNLGFSPEDREEN 109 +G T++LTG +GK ++ AL+ L G +L GD +R L+ LGF+ EDR N Sbjct: 395 QGFTIFLTGYMNSGKDAIARALQVTLNQQGGRSVSLLLGDTVRHELSSELGFTREDRHTN 454 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRD 169 ++RIA VA AG I + I+PY + R AR A FF V V PL CEQ D Sbjct: 455 IQRIAFVATELTRAGAAVIAAPIAPYEESRKFARDAVSQAG-SFFLVHVATPLEHCEQSD 513 Query: 170 VKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER 223 +G+Y AR GEIKGFTG+D YE PE +LV+ V V +++ +L+ + Sbjct: 514 KRGIYAAARRGEIKGFTGVDDPYETPEKADLVVDFSKQSVRSIVHEIILVLESQ 567 >1V47-A nrPDB Length = 349 Score = 123 bits (308), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 112/370 (30%), Positives = 171/370 (46%), Gaps = 34/370 (9%) Query: 252 ETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLT 311 ETLPAL+I + + ++ LA G P+ GFM E L H L G V ++PI+L Sbjct: 3 ETLPALEIGEDERLDLENLATGAFFPVKGFMTREEALSVAHEMRLPTGEV--WTIPILLQ 60 Query: 312 ATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVME 371 +K R+ AL++ G RVA+L E +E E +GT + HP + + Sbjct: 61 --FREKPRVGPGNTVALLHGGERVALLHVAEAYELDLEALARAVFGTDSETHPGVARLYG 118 Query: 372 QGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALL 431 +G + + G ++VL + L++ TP E++ F+ V AFQ RN H H L Sbjct: 119 KGPYALAGRVEVL-KPRPRTPLEK---TPEEVRAFFRQRGWRKVVAFQTRNAPHRAHEYL 174 Query: 432 MQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVVAIF 491 ++ + L G +L+HP+ G K DD P ++ + A++ + L E Sbjct: 175 IRLGLE--LADG-----VLVHPILGAKKPDDFPTEVIVEAYQALIRD-FLPQERVAFFGL 226 Query: 492 PSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAPG 551 +PM YAGP E +H R GA ++VGRD AG+ D Y+P ++ P Sbjct: 227 ATPMRYAGPKEAVFHALVRKNFGATHFLVGRDHAGV------GDFYDPYAAHRIFDRLPP 280 Query: 552 LITLEIVPFRVAAY-------NKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEG 604 L +EIV +V A +R H E IS T++R L REG+ PP Sbjct: 281 L-GIEIV--KVGAVFHCPLCGGIASERT--CPEGHREKRTAISMTKVRALLREGKAPPSE 335 Query: 605 FMAPKAWTVL 614 + P+ +L Sbjct: 336 LVRPELLPIL 345 >1J70-A nrPDB Length = 514 Score = 122 bits (305), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 101/362 (27%), Positives = 166/362 (45%), Gaps = 32/362 (8%) Query: 267 VQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAF 326 ++++ G +PL GF+ E +Y + L DG + ++PI L ++ T Sbjct: 48 IELILNGGFSPLTGFLNENDYSSVVTDSRLADGTL--WTIPITLDVDEAFANQIKPDTRI 105 Query: 327 ALMYEGR-RVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVME-QGDWLIGGDLQV- 383 AL + +AIL + ++ K + + + HP I + GD+ +GG L+ Sbjct: 106 ALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDPE-HPAISYLFNVAGDYYVGGSLEAI 164 Query: 384 -LDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLER 442 L + Y GL R TP +L+ +F+ D V AFQ RNP+H H ++L R Sbjct: 165 QLPQHYDYPGL---RKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAH--------RELTVR 213 Query: 443 GYR--RPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLE---EGVLNPETTVVAIFPSPMMY 497 R +L+HP+ G TK D+ R++ + +++ G+ +++ P M Sbjct: 214 AAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGI-----AFLSLLPLAMRM 268 Query: 498 AGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEI 557 +G E WH R GA+ +IVGRD AG G D Y P +++ + +E+ Sbjct: 269 SGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGPYDAQELVESYKHELDIEV 328 Query: 558 VPFRVAAYNKKKKR---MDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVL 614 VPFR+ Y + R +D D+ ISGT +R+ R G + PE F P+ +L Sbjct: 329 VPFRMVTYLPDEDRYAPIDQIDTTKTRTLN-ISGTELRRRLRVGGEIPEWFSYPEVVKIL 387 Query: 615 TE 616 E Sbjct: 388 RE 389 >1R6X-A nrPDB Length = 395 Score = 121 bits (303), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 101/362 (27%), Positives = 166/362 (45%), Gaps = 32/362 (8%) Query: 267 VQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAF 326 ++++ G +PL GF+ E +Y + L DG + ++PI L ++ T Sbjct: 44 IELILNGGFSPLTGFLNENDYSSVVTDSRLADGTL--WTIPITLDVDEAFANQIKPDTRI 101 Query: 327 ALMYEGR-RVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVME-QGDWLIGGDLQV- 383 AL + +AIL + ++ K + + + HP I + GD+ +GG L+ Sbjct: 102 ALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDPE-HPAISYLFNVAGDYYVGGSLEAI 160 Query: 384 -LDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLER 442 L + Y GL R TP +L+ +F+ D V AFQ RNP+H H ++L R Sbjct: 161 QLPQHYDYPGL---RKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAH--------RELTVR 209 Query: 443 GYRRP--VLLLHPLGGWTKDDDVPLMWRMKQHAAVLE---EGVLNPETTVVAIFPSPMMY 497 R +L+HP+ G TK D+ R++ + +++ G+ +++ P M Sbjct: 210 AAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGI-----AFLSLLPLAMRM 264 Query: 498 AGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEI 557 +G E WH R GA+ +IVGRD AG G D Y P +++ + +E+ Sbjct: 265 SGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGPYDAQELVESYKHELDIEV 324 Query: 558 VPFRVAAYNKKKKR---MDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVL 614 VPFR+ Y + R +D D+ ISGT +R+ R G + PE F P+ +L Sbjct: 325 VPFRMVTYLPDEDRYAPIDQIDTTKTRTLN-ISGTELRRRLRVGGEIPEWFSYPEVVKIL 383 Query: 615 TE 616 E Sbjct: 384 RE 385 >3NHB-A nrPDB Length = 306 Score = 33.1 bits (74), Expect = 0.38, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 7/59 (11%) Query: 52 GCTVWLTGLSGAGKTTV-SMALEEYLVCHGIPCYTLDGDNIRQ----GLNKNLGFSPED 105 G T+ L G SGAGK+T+ + Y + G C +DG +I Q L ++G P+D Sbjct: 80 GQTLALVGPSGAGKSTILRLLFRFYDISSG--CIRIDGQDISQVTQASLRSHIGVVPQD 136 >5L3R-A nrPDB Length = 301 Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust. Identities = 17/39 (43%), Positives = 19/39 (48%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 + L GL G GKTTV L YL G C + GD R Sbjct: 108 VILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYR 146 >2I3B-A nrPDB Length = 189 Score = 32.3 bits (72), Expect = 0.63, Method: Composition-based stats. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGF 101 V+LTG G GKTT+ E L G+P + +RQG + +GF Sbjct: 4 VFLTGPPGVGKTTLIHKASEVLKSSGVPVDGFYTEEVRQG-GRRIGF 49 >3A4L-A nrPDB Length = 260 Score = 32.3 bits (72), Expect = 0.64, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGL 95 + LTGL G GK+T S L + L + I L D IR+ Sbjct: 7 IILTGLPGVGKSTFSKNLAKILSKNNIDVIVLGSDLIRESF 47 >2P5T-B nrPDB Length = 253 Score = 32.0 bits (71), Expect = 0.84, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 33 HHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 H ++RN R G + + + L G SGAGKTT+ ++ + + +DGD+ R Sbjct: 13 HALARNLRSLTRGKKSSKQPIAILLGGQSGAGKTTIHRIKQKEFQGNIV---IIDGDSFR 69 >3E70-C nrPDB Length = 328 Score = 32.0 bits (71), Expect = 0.92, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 7/60 (11%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRI 113 + G +G+GKTT L +L HG D R G + E EE+ +RI Sbjct: 131 VIMFVGFNGSGKTTTIAKLANWLKNHGFSVVIAASDTFRAG-------AIEQLEEHAKRI 183 >3TCQ-A nrPDB Length = 326 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 22/35 (62%) Query: 211 DCVQQVVELLQERDIVPVDASYEVKELYVPENKLH 245 D +Q +V L+Q+ IVP+D + + + VPE +H Sbjct: 235 DKIQTIVNLMQDFKIVPIDPAKSIIGIEVPELLVH 269 >3KFL-A nrPDB Length = 564 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 401 TELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERG 443 +E KQ F++MN D + + NP H L+QD K+L +G Sbjct: 99 SEFKQCFQEMNYDMNYFIRTTNPTHEK---LVQDIWKKLAAKG 138 >2G77-B nrPDB Length = 198 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 399 TPTELKQKFKDMNADAVFAFQLRNPVHNGH--ALLMQDTHK 437 PT+L QKF D ++ +F +NP N H A+ M HK Sbjct: 154 VPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHK 194 >1Z06-A nrPDB Length = 189 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 399 TPTELKQKFKDMNADAVFAFQLRNPVHNGH--ALLMQDTHK 437 PT+L QKF D ++ +F +NP N H A+ M HK Sbjct: 145 VPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHK 185 >4AYX-A nrPDB Length = 595 Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 29/97 (29%) Query: 52 GCTVWLTGLSGAGKTTV-SMALEEYLVCHGIPCYTLDGDNIRQ----------------- 93 G L G SG+GK+TV S+ L Y G +LDG +IRQ Sbjct: 370 GSVTALVGPSGSGKSTVLSLLLRLYDPASG--TISLDGHDIRQLNPVWLRSKIGTVSQEP 427 Query: 94 -----GLNKNLGFSPED----REENVRRIAEVAKLFA 121 + +N+ + +D E ++R+AEVA A Sbjct: 428 ILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVA 464 >4QIW-C nrPDB Length = 391 Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust. Identities = 25/61 (40%), Positives = 32/61 (52%), Gaps = 9/61 (14%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSP-EDREENVRRIAE 115 L GLSG GKT + +EY++ YT +G N +Q L K G P R N+ IAE Sbjct: 223 LKGLSGVGKTIIRKEGDEYVI------YT-EGSNFKQVL-KVPGVDPTRTRTNNIWEIAE 274 Query: 116 V 116 V Sbjct: 275 V 275 >6BBQ-A nrPDB Length = 520 Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 38 NKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNK 97 NK+G+V+ G + + + GL AGKTT+ L+ IP G N+ K Sbjct: 345 NKKGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTV---GFNVETVTYK 401 Query: 98 NLGFSPED 105 N+ F+ D Sbjct: 402 NVKFNVWD 409 >4EUN-A nrPDB Length = 200 Score = 29.3 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 29/188 (15%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDG----DNIRQGLNKNLGFSPEDREENV 110 V + G+SG+GKTT++ + + G+ D +NI + + + + EDR + Sbjct: 32 VVVMGVSGSGKTTIAHGVADET---GLEFAEADAFHSPENIAT-MQRGIPLTDEDRWPWL 87 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEG-ASLPFFEVFVDAPLHVCEQRD 169 R +AE ADAG +++ I+ R + EG S+ F +D P V Sbjct: 88 RSLAEWMDARADAG---VSTIITCSALKRTYRDVLREGPPSVDFLH--LDGPAEV----- 137 Query: 170 VKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER-----D 224 +KG K R G + + S+ EA L+ D + ++Q E L ER D Sbjct: 138 IKGRMSK-REGHFMPASLLQSQLATLEA----LEPDESGIVLDLRQPPEQLIERALTWLD 192 Query: 225 IVPVDASY 232 I P A++ Sbjct: 193 IAPAVATH 200 >5HJR-A nrPDB Length = 857 Score = 29.3 bits (64), Expect = 6.1, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 7/84 (8%) Query: 344 FEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQV--LDRVY-WNDGLDQYRLTP 400 FEH++ R W T K H K G +G D + ++ VY + D RL Sbjct: 146 FEHQRAPREPGAWEETFKTHSDSK---PYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKV 202 Query: 401 TELKQKFKDMNADAVFAFQLRNPV 424 TE + ++ N D VF ++L NP+ Sbjct: 203 TEGGEPYRLYNLD-VFQYELNNPM 225 >5XF8-3 nrPDB Length = 997 Score = 28.9 bits (63), Expect = 6.2, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 105 DREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHE 147 DRE RR+ A + AD G+VCI F DR ++ E Sbjct: 475 DRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVME 517 >1WDT-A nrPDB Length = 665 Score = 28.9 bits (63), Expect = 6.2, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 44 VGTRGGFRGCTVWLTGLSGAGKTTVSMAL 72 +GT GG TV L G +G+GKTT++ AL Sbjct: 1 MGTEGGAMIRTVALVGHAGSGKTTLTEAL 29 >2F6K-A nrPDB Length = 307 Score = 28.9 bits (63), Expect = 7.2, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%) Query: 555 LEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKL 594 L IV R+A Y +K ++D YD HH F+ R+L Sbjct: 210 LGIVDDRIAQYAQKVYQVDVYDVMHHVYFDVAGAVLPRQL 249 >4OI0-A nrPDB Length = 431 Score = 28.9 bits (63), Expect = 7.2, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 27/64 (42%) Query: 17 AQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYL 76 A++ M N+ V + + Q G +G + L G + GKTTVS L Y Sbjct: 82 AESTPMVIYLNIHAAMEEVRKKREEQAAGNSNKAKGPRLLLVGPTDVGKTTVSRILCNYS 141 Query: 77 VCHG 80 V G Sbjct: 142 VRQG 145 >3BZN-A nrPDB Length = 431 Score = 28.5 bits (62), Expect = 8.2, Method: Compositional matrix adjust. Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 2/81 (2%) Query: 302 INLSVPIVLTATHEDKERLD-GCTAFALMYEGRRVAILRNPEFFEHRKEERCARQ-WGTT 359 ++ + P+ A RL+ C F + ++G + +PE R+++ + T Sbjct: 199 LHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGT 258 Query: 360 CKNHPYIKMVMEQGDWLIGGD 380 N+P K + G+WL+ D Sbjct: 259 VANNPDDKQAQQLGEWLMADD 279 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1X6V-B nrPDB 1010 0.0 2QJF-A nrPDB 614 e-176 4MAF-A nrPDB 518 e-147 1I2D-A nrPDB 461 e-130 4DNX-A nrPDB 458 e-129 1JHD-A nrPDB 452 e-127 1J70-A nrPDB 449 e-126 2GKS-A nrPDB 443 e-124 1R6X-A nrPDB 441 e-124 1V47-A nrPDB 383 e-106 2OFX-A nrPDB 359 3e-99 2AX4-A nrPDB 330 8e-91 2PEY-A nrPDB 315 3e-86 1M7G-A nrPDB 294 8e-80 6C6B-A nrPDB 293 2e-79 3UIE-A nrPDB 278 4e-75 3CR7-A nrPDB 272 3e-73 4BZX-A nrPDB 252 3e-67 2YVU-A nrPDB 247 1e-65 5CB6-A nrPDB 246 2e-65 3CR8-A nrPDB 238 6e-63 Sequences not found previously or not previously below threshold: 3A4L-A nrPDB 47 2e-05 2P5T-B nrPDB 41 0.002 1KNQ-A nrPDB 40 0.003 4EUN-A nrPDB 39 0.010 5L3R-A nrPDB 38 0.010 4CVN-A nrPDB 38 0.013 3E70-C nrPDB 37 0.018 1KAG-A nrPDB 37 0.023 3B5X-A nrPDB 37 0.031 6CUM-A nrPDB 36 0.041 1G3Q-A nrPDB 35 0.097 2V3C-C nrPDB 35 0.11 5L3R-B nrPDB 35 0.13 2OG2-A nrPDB 35 0.13 2I3B-A nrPDB 35 0.14 4D4L-A nrPDB 35 0.14 3TRF-A nrPDB 34 0.15 3TK1-A nrPDB 34 0.16 2PT5-A nrPDB 34 0.16 1VIA-A nrPDB 34 0.22 2DWP-A nrPDB 34 0.22 1ION-A nrPDB 34 0.22 6FRK-x nrPDB 34 0.25 5L3Q-A nrPDB 34 0.25 3JAJ-z nrPDB 34 0.25 1A7J-A nrPDB 34 0.27 4Y0A-A nrPDB 34 0.32 2WWW-A nrPDB 33 0.32 3T61-A nrPDB 33 0.40 3MD0-A nrPDB 33 0.46 3VAA-A nrPDB 33 0.46 4JMP-A nrPDB 33 0.48 5MKK-B nrPDB 33 0.51 3PXU-A nrPDB 33 0.54 3UX8-A nrPDB 33 0.54 2R6F-A nrPDB 33 0.54 5OCH-A nrPDB 32 0.55 3C8U-A nrPDB 32 0.61 4XRP-A nrPDB 32 0.61 4AK9-A nrPDB 32 0.67 5L3S-A nrPDB 32 0.69 5DGX-A nrPDB 32 0.69 4CVK-A nrPDB 32 0.71 1QZX-A nrPDB 32 0.75 4OQS-A nrPDB 32 0.76 4G1U-C nrPDB 32 0.79 1IHU-A nrPDB 32 0.80 5HTK-A nrPDB 32 0.81 1RZ3-A nrPDB 32 0.88 4OQR-A nrPDB 32 0.91 3DM5-A nrPDB 32 0.99 5EG1-A nrPDB 32 1.1 2F6R-A nrPDB 32 1.1 2PH1-A nrPDB 32 1.1 3NXS-A nrPDB 32 1.2 2IY3-A nrPDB 31 1.3 1WDT-A nrPDB 31 1.4 1RJ9-B nrPDB 31 1.4 2FFH-A nrPDB 31 1.5 5HCI-A nrPDB 31 1.5 2IYT-A nrPDB 31 1.6 5HR5-A nrPDB 31 1.7 3HJS-A nrPDB 31 1.7 5X7J-A nrPDB 31 1.9 4JYC-A nrPDB 31 1.9 5EUM-A nrPDB 31 1.9 4X4R-A nrPDB 31 2.0 5AUQ-A nrPDB 30 2.2 2IXE-A nrPDB 30 2.2 1ZU4-A nrPDB 30 2.2 4JLV-A nrPDB 30 2.9 6G2G-A nrPDB 30 3.0 3KB1-A nrPDB 30 3.9 5XF8-3 nrPDB 30 4.3 3X1M-A nrPDB 29 5.8 3LD9-A nrPDB 29 7.2 5CA0-F nrPDB 29 7.5 >1X6V-B nrPDB Length = 630 Score = 1010 bits (2612), Expect = 0.0, Method: Composition-based stats. Identities = 623/624 (99%), Positives = 623/624 (99%) Query: 1 MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL 60 MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL Sbjct: 1 MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL 60 Query: 61 SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF 120 SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF Sbjct: 61 SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF 120 Query: 121 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG 180 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG Sbjct: 121 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG 180 Query: 181 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP 240 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP Sbjct: 181 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP 240 Query: 241 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG Sbjct: 241 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300 Query: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC 360 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC Sbjct: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC 360 Query: 361 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL 420 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAV AFQL Sbjct: 361 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVSAFQL 420 Query: 421 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV 480 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV Sbjct: 421 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV 480 Query: 481 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS 540 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS Sbjct: 481 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS 540 Query: 541 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK 600 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK Sbjct: 541 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK 600 Query: 601 PPEGFMAPKAWTVLTEYYKSLEKA 624 PPEGFMAPKAWTVLTEYYKSLEKA Sbjct: 601 PPEGFMAPKAWTVLTEYYKSLEKA 624 >2QJF-A nrPDB Length = 405 Score = 614 bits (1582), Expect = e-176, Method: Composition-based stats. Identities = 405/405 (100%), Positives = 405/405 (100%) Query: 220 LQERDIVPVDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLN 279 LQERDIVPVDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLN Sbjct: 1 LQERDIVPVDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLN 60 Query: 280 GFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILR 339 GFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILR Sbjct: 61 GFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILR 120 Query: 340 NPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLT 399 NPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLT Sbjct: 121 NPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLT 180 Query: 400 PTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTK 459 PTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTK Sbjct: 181 PTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTK 240 Query: 460 DDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYI 519 DDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYI Sbjct: 241 DDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYI 300 Query: 520 VGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEH 579 VGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEH Sbjct: 301 VGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEH 360 Query: 580 HEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA 624 HEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA Sbjct: 361 HEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA 405 >4MAF-A nrPDB Length = 404 Score = 518 bits (1335), Expect = e-147, Method: Composition-based stats. Identities = 236/393 (60%), Positives = 294/393 (74%), Gaps = 4/393 (1%) Query: 233 EVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLH 292 ++ EL V + + L K +A +LP +K++++D++WV VL+EGWATPL GFMRE E+LQ LH Sbjct: 9 KLVELVVTDFERDLKKGEALSLPRIKLSRIDLEWVHVLSEGWATPLKGFMREAEFLQTLH 68 Query: 293 FD--CLLDGGVINLSVPIVLTATHEDKERLDGCTAFALM-YEGRRVAILRNPEFFEHRKE 349 F+ L DG V+N+SVPIVL K R+ AL +G VAIL N E ++H KE Sbjct: 69 FNSLRLDDGSVVNMSVPIVLAIDDAQKHRIGDNKKVALFDSKGDPVAILNNIEIYKHPKE 128 Query: 350 ERCARQWGTTCKNHPYI-KMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFK 408 ER AR WGT PY+ + + G+WLIGGDL+V++ + +NDGLD +RL+PT+L+ +F Sbjct: 129 ERIARTWGTIAPGLPYVEQTITNAGNWLIGGDLEVIEPIQYNDGLDHFRLSPTQLRAEFT 188 Query: 409 DMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWR 468 NADAVFAFQLRNPVHNGHALLM DT K+LLE GY+ PVLLLHPLGG+TK DDVPL WR Sbjct: 189 RRNADAVFAFQLRNPVHNGHALLMTDTRKRLLEMGYKNPVLLLHPLGGYTKADDVPLDWR 248 Query: 469 MKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMP 528 MKQH VLE+GVL+PETTVV+IFPSPM YAGPTEVQWH +AR+ AGANFYIVGRDPAGM Sbjct: 249 MKQHEKVLEDGVLDPETTVVSIFPSPMHYAGPTEVQWHAKARINAGANFYIVGRDPAGMS 308 Query: 529 HPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISG 588 HP +DLY+ HG KVL+MAPGL L I+PFRVAAY+K + +M ++D +DF FISG Sbjct: 309 HPVEKRDLYDADHGKKVLSMAPGLERLNILPFRVAAYDKTQGKMAFFDPSRPQDFLFISG 368 Query: 589 TRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSL 621 T+MR LAR + PP+GFM P W VL +YY SL Sbjct: 369 TKMRTLARNKESPPDGFMCPGGWKVLVDYYDSL 401 >1I2D-A nrPDB Length = 573 Score = 461 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 101/375 (26%), Positives = 168/375 (44%), Gaps = 16/375 (4%) Query: 247 AKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSV 306 +AE+LPA+ + + + ++++ G +PL GFM + +Y + + L DG V S+ Sbjct: 24 LAAEAESLPAVTLTERQLCDLELIMNGGFSPLEGFMNQADYDRVCEDNRLADGNV--FSM 81 Query: 307 PIVLTATHE--DKERLDGCTAFAL--MYEGRRVAILRNPEFFEHRKEERCARQWGTTCKN 362 PI L A+ E D+++L + L + R +AIL + + K + +G ++ Sbjct: 82 PITLDASQEVIDEKKLQAGSRITLRDFRDDRNLAILTIDDIYRPDKTKEAKLVFGGDPEH 141 Query: 363 HPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRN 422 + + ++ IGG ++ ++++ D + R TP EL+ F + V AFQ RN Sbjct: 142 PAIVYLNNTVKEFYIGGKIEAVNKLNHYDYV-ALRYTPAELRVHFDKLGWSRVVAFQTRN 200 Query: 423 PVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLN 482 P+H H L + R+ +L+HP+ G TK D+ R++ + A+L Sbjct: 201 PMHRAHRELTVRAARS------RQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPR--YP 252 Query: 483 PETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHG 542 V+ + M GP E WH R GA +IVGRD AG G+D Y P Sbjct: 253 NGMAVLGLLGLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGSNSKGEDFYGPYDA 312 Query: 543 AKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEF-ISGTRMRKLAREGQKP 601 + + +E+V F++ Y D ISGT +R+ R G Sbjct: 313 QHAVEKYKDELGIEVVEFQMVTYLPDTDEYRPVDQVPAGVKTLNISGTELRRRLRSGAHI 372 Query: 602 PEGFMAPKAWTVLTE 616 PE F P+ +L E Sbjct: 373 PEWFSYPEVVKILRE 387 Score = 210 bits (534), Expect = 2e-54, Method: Composition-based stats. Identities = 70/177 (39%), Positives = 98/177 (55%), Gaps = 2/177 (1%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLD-GDNIRQGLNKNLGFSPEDREEN 109 +G T++LTG +GK ++ AL+ L G +L GD +R L+ LGF+ EDR N Sbjct: 395 QGFTIFLTGYMNSGKDAIARALQVTLNQQGGRSVSLLLGDTVRHELSSELGFTREDRHTN 454 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRD 169 ++RIA VA AG I + I+PY + R AR A FF V V PL CEQ D Sbjct: 455 IQRIAFVATELTRAGAAVIAAPIAPYEESRKFARDAVSQAG-SFFLVHVATPLEHCEQSD 513 Query: 170 VKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 226 +G+Y AR GEIKGFTG+D YE PE +LV+ V V +++ +L+ + + Sbjct: 514 KRGIYAAARRGEIKGFTGVDDPYETPEKADLVVDFSKQSVRSIVHEIILVLESQGFL 570 >4DNX-A nrPDB Length = 397 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 124/417 (29%), Positives = 194/417 (46%), Gaps = 38/417 (9%) Query: 225 IVPVDASYEVKE--LYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFM 282 I PV S E++ +Y PE H ++AE+LP++ ++ +L G+ +PL+GFM Sbjct: 2 IKPV-GSDELRPRFVYDPEQH-HRLSSEAESLPSVIVSSQAAGNAVMLGAGYFSPLDGFM 59 Query: 283 REREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALM---YEGRRVAILR 339 + L L DG P+ L E + + G T AL EG V + Sbjct: 60 NLADALSSAQSMTLTDGRFF----PVPLLCLLESADAIAGATRIALRDPNVEGNPVLAVM 115 Query: 340 NPEFFEHRKEERCA----RQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWN-DGLD 394 + E + + A + +GT+ HP ++ QG I G +QVL+ Y+ D D Sbjct: 116 DVTAVEQVSDAQMALMTEQVYGTSDPKHPGVETFNSQGRTAISGPIQVLNFSYFQTDFPD 175 Query: 395 QYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPL 454 +R T E++ + ++ + AFQ RNP+H H L + + + G +++H L Sbjct: 176 TFR-TAVEIRHEIQERGWQKIVAFQTRNPMHRAHEELCKMAMEAVEADG-----VVIHML 229 Query: 455 GGWTKDDDVPLMWRMKQHAAV--LEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMV 512 G K D+P R AA+ + E P T +V + M+YAGP E H R Sbjct: 230 LGQLKPGDIPAPVR---DAAIRTMAELYFPPNTVMVTGYGFDMLYAGPREAVLHAYFRQN 286 Query: 513 AGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRV--AAYNKKKK 570 GA +I+GRD AG+ D Y P + A L I FR AY+KK Sbjct: 287 MGATHFIIGRDHAGVG------DYYGPFDAQTIFDDAVPTDVLAIEIFRADNTAYSKKLG 340 Query: 571 R-MDYYDSEHH--EDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA 624 R + D+ H +DF +SGTR+R++ +G+ PP F P+ +L +YY+SL ++ Sbjct: 341 RVVMMRDAPDHTPDDFIQLSGTRVREMLGQGEAPPPEFSRPEVAQILMDYYRSLPQS 397 >1JHD-A nrPDB Length = 396 Score = 452 bits (1164), Expect = e-127, Method: Composition-based stats. Identities = 122/414 (29%), Positives = 187/414 (45%), Gaps = 38/414 (9%) Query: 225 IVPVDASYEVKEL--YVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFM 282 I PV S E+K L Y PE H +AE+LP++ I+ ++ G+ +PL GFM Sbjct: 2 IKPV-GSDELKPLFVYDPEEH-HKLSHEAESLPSVVISSQAAGNAVMMGAGYFSPLQGFM 59 Query: 283 REREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALM---YEGRRVAILR 339 + + L DG P+ + E+ + + AL EG V + Sbjct: 60 NVADAMGAAEKMTLSDGSFF----PVPVLCLLENTDAIGDAKRIALRDPNVEGNPVLAVM 115 Query: 340 NPEFFEHRKEERCA----RQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWN-DGLD 394 + E E +E+ A + + TT +H +K QG + G +QVL+ Y+ D D Sbjct: 116 DIEAIEEVSDEQMAVMTDKVYRTTDMDHIGVKTFNSQGRVAVSGPIQVLNFSYFQADFPD 175 Query: 395 QYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPL 454 +R T E++ + K+ V AFQ RNP+H H L + + L G +++H L Sbjct: 176 TFR-TAVEIRNEIKEHGWSKVVAFQTRNPMHRAHEELCRMAMESLDADG-----VVVHML 229 Query: 455 GGWTKDDDVPLMWRMKQHAAV--LEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMV 512 G K D+P R AA+ + E P T +V + M+YAGP E H R Sbjct: 230 LGKLKKGDIPAPVR---DAAIRTMAEVYFPPNTVMVTGYGFDMLYAGPREAVLHAYFRQN 286 Query: 513 AGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTM--APGLITLEIVPFRVAAYNKK-K 569 GA +I+GRD AG+ D Y + G + +EI AY+KK Sbjct: 287 MGATHFIIGRDHAGVG------DYYGAFDAQTIFDDEVPEGAMEIEIFRADHTAYSKKLN 340 Query: 570 KRMDYYDSEHH--EDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSL 621 K + D H EDF +SGT++R++ +G PP F P+ +L +YY+S+ Sbjct: 341 KIVMMRDVPDHTKEDFVLLSGTKVREMLGQGIAPPPEFSRPEVAKILMDYYQSI 394 >1J70-A nrPDB Length = 514 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 95/386 (24%), Positives = 165/386 (42%), Gaps = 16/386 (4%) Query: 243 KLHLAKTDAETLPALK--INKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300 K + ++A++ L + + ++++ G +PL GF+ E +Y + L DG Sbjct: 22 KKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGT 81 Query: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGR-RVAILRNPEFFEHRKEERCARQWGTT 359 + ++PI L ++ T AL + +AIL + ++ K + + Sbjct: 82 L--WTIPITLDVDEAFANQIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGD 139 Query: 360 CKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQ 419 ++ + GD+ +GG L+ + D R TP +L+ +F+ D V AFQ Sbjct: 140 PEHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPG-LRKTPAQLRLEFQSRQWDRVVAFQ 198 Query: 420 LRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEG 479 RNP+H H L ++ +L+HP+ G TK D+ R++ + +++ Sbjct: 199 TRNPMHRAHRELTVRAARE------ANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKR- 251 Query: 480 VLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEP 539 +++ P M +G E WH R GA+ +IVGRD AG G D Y P Sbjct: 252 -YPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGP 310 Query: 540 SHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHED--FEFISGTRMRKLARE 597 +++ + +E+VPFR+ Y + R D ISGT +R+ R Sbjct: 311 YDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLNISGTELRRRLRV 370 Query: 598 GQKPPEGFMAPKAWTVLTEYYKSLEK 623 G + PE F P+ +L E K Sbjct: 371 GGEIPEWFSYPEVVKILRESNPPRPK 396 >2GKS-A nrPDB Length = 546 Score = 443 bits (1139), Expect = e-124, Method: Composition-based stats. Identities = 108/369 (29%), Positives = 175/369 (47%), Gaps = 14/369 (3%) Query: 254 LPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTAT 313 L +++I++ + +++LA G TPL+ FM E +Y + L G + +PI L Sbjct: 7 LKSIQISQRSVLDLELLAVGAFTPLDRFMGEEDYRNVVESMRLKSGTL--FPIPITLPME 64 Query: 314 HEDKERLDGCTAFALM-YEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQ 372 E + L L + +AI+R E ++ E GTT HP + + Sbjct: 65 KEIAKDLKEGEWIVLRDPKNVPLAIMRVEEVYKWNLEYEAKNVLGTTDPRHPLVAEMHTW 124 Query: 373 GDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLM 432 G++ I G+L+V+ + D + YR TP +++++ K + D + AFQ RNP+H H L Sbjct: 125 GEYYISGELKVIQLPKYYDFPE-YRKTPKQVREEIKSLGLDKIVAFQTRNPMHRVHEELT 183 Query: 433 QDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFP 492 + +++ LLLHP+ G TK DV + RM+ + VL E + + T++A P Sbjct: 184 KRAMEKV------GGGLLLHPVVGLTKPGDVDVYTRMRIYK-VLYEKYYDKKKTILAFLP 236 Query: 493 SPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAPGL 552 M AGP E WH R GA +IVGRD A GK Y+P ++ Sbjct: 237 LAMRMAGPREALWHGIIRRNYGATHFIVGRDHASPGKDSKGKPFYDPYEAQELFKKYEDE 296 Query: 553 ITLEIVPFRVAAYNKKKKRMDYYDSEHHE--DFEFISGTRMRK-LAREGQKPPEGFMAPK 609 I +++VPF Y + + + + ISGT +R+ ++G+K PE F P+ Sbjct: 297 IGIKMVPFEELVYVPELDQYVEINEAKKRNLKYINISGTEIRENFLKQGRKLPEWFTRPE 356 Query: 610 AWTVLTEYY 618 +L E Y Sbjct: 357 VAEILAETY 365 Score = 249 bits (635), Expect = 3e-66, Method: Composition-based stats. Identities = 78/178 (43%), Positives = 103/178 (57%), Gaps = 2/178 (1%) Query: 49 GFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREE 108 +G VWLTGL AGK+T++ L L G LDGD +R L++ LGFS EDR Sbjct: 369 HKQGFCVWLTGLPCAGKSTIAEILATMLQARGRKVTLLDGDVVRTHLSRGLGFSKEDRIT 428 Query: 109 NVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQR 168 N+ R+ VA V I + +SPY RN R + E F EVFVDAP+ VCE+R Sbjct: 429 NILRVGFVASEIVKHNGVVICALVSPYRSARNQVRNMMEEGK--FIEVFVDAPVEVCEER 486 Query: 169 DVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 226 DVKGLYKKA+ G IKGFTG+D YE P APE+ + T + +++E L++ + Sbjct: 487 DVKGLYKKAKEGLIKGFTGVDDPYEPPVAPEVRVDTTKLTPEESALKILEFLKKEGFI 544 >1R6X-A nrPDB Length = 395 Score = 441 bits (1133), Expect = e-124, Method: Composition-based stats. Identities = 95/386 (24%), Positives = 165/386 (42%), Gaps = 16/386 (4%) Query: 243 KLHLAKTDAETLPALK--INKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300 K + ++A++ L + + ++++ G +PL GF+ E +Y + L DG Sbjct: 18 KKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGT 77 Query: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGR-RVAILRNPEFFEHRKEERCARQWGTT 359 + ++PI L ++ T AL + +AIL + ++ K + + Sbjct: 78 L--WTIPITLDVDEAFANQIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGD 135 Query: 360 CKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQ 419 ++ + GD+ +GG L+ + D R TP +L+ +F+ D V AFQ Sbjct: 136 PEHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPG-LRKTPAQLRLEFQSRQWDRVVAFQ 194 Query: 420 LRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEG 479 RNP+H H L ++ +L+HP+ G TK D+ R++ + +++ Sbjct: 195 TRNPMHRAHRELTVRAARE------ANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKR- 247 Query: 480 VLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEP 539 +++ P M +G E WH R GA+ +IVGRD AG G D Y P Sbjct: 248 -YPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGP 306 Query: 540 SHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHED--FEFISGTRMRKLARE 597 +++ + +E+VPFR+ Y + R D ISGT +R+ R Sbjct: 307 YDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLNISGTELRRRLRV 366 Query: 598 GQKPPEGFMAPKAWTVLTEYYKSLEK 623 G + PE F P+ +L E K Sbjct: 367 GGEIPEWFSYPEVVKILRESNPPRPK 392 >1V47-A nrPDB Length = 349 Score = 383 bits (984), Expect = e-106, Method: Composition-based stats. Identities = 109/367 (29%), Positives = 167/367 (45%), Gaps = 26/367 (7%) Query: 252 ETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLT 311 ETLPAL+I + + ++ LA G P+ GFM E L H L G V ++PI+L Sbjct: 3 ETLPALEIGEDERLDLENLATGAFFPVKGFMTREEALSVAHEMRLPTGEV--WTIPILLQ 60 Query: 312 ATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVME 371 +K R+ AL++ G RVA+L E +E E +GT + HP + + Sbjct: 61 --FREKPRVGPGNTVALLHGGERVALLHVAEAYELDLEALARAVFGTDSETHPGVARLYG 118 Query: 372 QGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALL 431 +G + + G ++VL + L+ TP E++ F+ V AFQ RN H H L Sbjct: 119 KGPYALAGRVEVL-KPRPRTPLE---KTPEEVRAFFRQRGWRKVVAFQTRNAPHRAHEYL 174 Query: 432 MQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVVAIF 491 ++ + L G +L+HP+ G K DD P ++ + A++ + L E Sbjct: 175 IRLGLE--LADG-----VLVHPILGAKKPDDFPTEVIVEAYQALIRD-FLPQERVAFFGL 226 Query: 492 PSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTMAPG 551 +PM YAGP E +H R GA ++VGRD AG+ D Y+P ++ P Sbjct: 227 ATPMRYAGPKEAVFHALVRKNFGATHFLVGRDHAGVG------DFYDPYAAHRIFDRLPP 280 Query: 552 LITLEIVPFRVAAYNKKKKRM---DYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAP 608 L +EIV + + H E IS T++R L REG+ PP + P Sbjct: 281 L-GIEIVKVGAVFHCPLCGGIASERTCPEGHREKRTAISMTKVRALLREGKAPPSELVRP 339 Query: 609 KAWTVLT 615 + +L Sbjct: 340 ELLPILR 346 >2OFX-A nrPDB Length = 207 Score = 359 bits (920), Expect = 3e-99, Method: Composition-based stats. Identities = 203/203 (100%), Positives = 203/203 (100%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 84 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY Sbjct: 5 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 64 Query: 85 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 144 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ Sbjct: 65 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 124 Query: 145 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKT 204 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKT Sbjct: 125 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKT 184 Query: 205 DSCDVNDCVQQVVELLQERDIVP 227 DSCDVNDCVQQVVELLQERDIVP Sbjct: 185 DSCDVNDCVQQVVELLQERDIVP 207 >2AX4-A nrPDB Length = 198 Score = 330 bits (847), Expect = 8e-91, Method: Composition-based stats. Identities = 164/197 (83%), Positives = 181/197 (91%) Query: 31 QAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDN 90 QAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTT+S ALEEYLV H IPCY+LDGDN Sbjct: 1 QAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDN 60 Query: 91 IRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGAS 150 +R GLN+NLGFSP DREEN+RRIAEVAKLFADAGLVCITSFISP+ +DR NAR+IHE A Sbjct: 61 VRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAG 120 Query: 151 LPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVN 210 LPFFE+FVDAPL++CE RDVKGLYK+ARAGEIKGFTGIDS+YEKPE PE VLKT+ V+ Sbjct: 121 LPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVS 180 Query: 211 DCVQQVVELLQERDIVP 227 DCV QVVELLQE++IVP Sbjct: 181 DCVHQVVELLQEQNIVP 197 >2PEY-A nrPDB Length = 179 Score = 315 bits (808), Expect = 3e-86, Method: Composition-based stats. Identities = 177/179 (98%), Positives = 177/179 (98%) Query: 48 GGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDRE 107 G RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDRE Sbjct: 1 GHMRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDRE 60 Query: 108 ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQ 167 ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQ Sbjct: 61 ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQ 120 Query: 168 RDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 226 RDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV Sbjct: 121 RDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 179 >1M7G-A nrPDB Length = 211 Score = 294 bits (752), Expect = 8e-80, Method: Composition-based stats. Identities = 109/214 (50%), Positives = 143/214 (66%), Gaps = 11/214 (5%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVC-HGIPC 83 +TN+T+ A ++R++R ++ RG T+WLTGLS +GK+T+++ LE LV + Sbjct: 2 STNITFHASALTRSERTELRNQRG----LTIWLTGLSASGKSTLAVELEHQLVRDRRVHA 57 Query: 84 YTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNAR 143 Y LDGDNIR GLNK+LGFS DR EN+RRIAEVAKLFAD+ + ITSFISPY +DR+ AR Sbjct: 58 YRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTAR 117 Query: 144 QIHE------GASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEA 197 Q+HE LPF EV+VD P+ V EQRD KGLYKKAR G IK FTGI + YE P Sbjct: 118 QLHEVATPGEETGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPAN 177 Query: 198 PELVLKTDSCDVNDCVQQVVELLQERDIVPVDAS 231 PE+ +K V D V+Q+++ L + +P Sbjct: 178 PEVHVKNYELPVQDAVKQIIDYLDTKGYLPAKKE 211 >6C6B-A nrPDB Length = 211 Score = 293 bits (750), Expect = 2e-79, Method: Composition-based stats. Identities = 105/206 (50%), Positives = 145/206 (70%), Gaps = 6/206 (2%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 84 ATN+T+ V++++R ++G +G CTVWLTGLS +GK+T++ ALE++L+ + Y Sbjct: 10 ATNITFHPGAVTQDERDTLLGQKG----CTVWLTGLSASGKSTIATALEQHLLHKKLHAY 65 Query: 85 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 144 LDGDNIR GLNK+LGF R EN+RRI EV+ LFA + + +T+FISPY DR AR+ Sbjct: 66 RLDGDNIRFGLNKDLGFDQASRVENIRRIGEVSLLFALSSTISVTAFISPYISDRQLARE 125 Query: 145 IHE--GASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVL 202 +HE +++PF EVF+DAPL V EQRD KGLYKKARAGEIK FTGI + YE P PE+ + Sbjct: 126 LHEKHSSAIPFIEVFIDAPLSVVEQRDPKGLYKKARAGEIKDFTGISAPYEAPANPEIHI 185 Query: 203 KTDSCDVNDCVQQVVELLQERDIVPV 228 +TD DV V+ + + L + ++P Sbjct: 186 RTDEVDVAGAVEIITKYLADNGLIPA 211 >3UIE-A nrPDB Length = 200 Score = 278 bits (712), Expect = 4e-75, Method: Composition-based stats. Identities = 96/205 (46%), Positives = 129/205 (62%), Gaps = 7/205 (3%) Query: 25 ATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCY 84 +TN+ + V + R +++ +G C +W+TGLSG+GK+T++ AL + L G CY Sbjct: 2 STNIKWHECSVEKVDRQRLLDQKG----CVIWVTGLSGSGKSTLACALNQMLYQKGKLCY 57 Query: 85 TLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQ 144 LDGDN+R GLN++L F EDR EN+RR+ EVAKLFADAG++CI S ISPY DR+ R Sbjct: 58 ILDGDNVRHGLNRDLSFKAEDRAENIRRVGEVAKLFADAGIICIASLISPYRTDRDACRS 117 Query: 145 IHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVL-K 203 + F EVF+D PL VCE RD KGLYK ARAG+IKGFTGID YE P E+ L + Sbjct: 118 LLPEG--DFVEVFMDVPLSVCEARDPKGLYKLARAGKIKGFTGIDDPYEPPLNCEISLGR 175 Query: 204 TDSCDVNDCVQQVVELLQERDIVPV 228 + ++VV L + + Sbjct: 176 EGGTSPIEMAEKVVGYLDNKGYLQA 200 >3CR7-A nrPDB Length = 197 Score = 272 bits (695), Expect = 3e-73, Method: Composition-based stats. Identities = 104/190 (54%), Positives = 129/190 (67%), Gaps = 7/190 (3%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVC-HGIPCYTLDGDNIRQGLNKNLGFSPEDREEN 109 RG T+WLTGLS +GK+T+++ LE LV + Y LDGDNIR GLNK+LGFS DR EN Sbjct: 2 RGLTIWLTGLSASGKSTLAVELEHQLVRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNEN 61 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHE------GASLPFFEVFVDAPLH 163 +RRIAEVAKLFAD+ + ITSFISPY +DR+ ARQ+HE LPF EV+VD P+ Sbjct: 62 IRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEVATPGEETGLPFVEVYVDVPVE 121 Query: 164 VCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER 223 V EQRD KGLYKKAR G IK FTGI + YE P PE+ +K V D V+Q+++ L + Sbjct: 122 VAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTK 181 Query: 224 DIVPVDASYE 233 +P E Sbjct: 182 GYLPAKKELE 191 >4BZX-A nrPDB Length = 173 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 91/172 (52%), Positives = 120/172 (69%), Gaps = 1/172 (0%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENV 110 RG TVW TGLSG+GK++V+M +E L+ GI Y LDGDN+R GLN +LGFS DR EN+ Sbjct: 3 RGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENL 62 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDV 170 RR++ VA L AD G + + ISP + R AR++H A + FFEVF D PL CE+RD Sbjct: 63 RRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDP 122 Query: 171 KGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQE 222 KGLY KARAGEI FTGIDS Y++P+ P+L L D +++ Q+V++LL+ Sbjct: 123 KGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDR-SIDEQAQEVIDLLES 173 >2YVU-A nrPDB Length = 186 Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats. Identities = 76/171 (44%), Positives = 107/171 (62%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENV 110 +G VWLTGL G+GKTT++ L + L G LDGD R +++ GF+ E+R ++ Sbjct: 12 KGIVVWLTGLPGSGKTTIATRLADLLQKEGYRVEVLDGDWARTTVSEGAGFTREERLRHL 71 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDV 170 +RIA +A+L A G++ I SF+SPY Q RN R+I E +PF E++V A L +RD Sbjct: 72 KRIAWIARLLARNGVIVICSFVSPYKQARNMVRRIVEEEGIPFLEIYVKASLEEVIRRDP 131 Query: 171 KGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQ 221 KGLYKKA GE++ FTGI YE PE P+LVL T+S + V + L++ Sbjct: 132 KGLYKKALKGELENFTGITDPYEPPENPQLVLDTESNTIEHNVSYLYSLVK 182 >5CB6-A nrPDB Length = 197 Score = 246 bits (628), Expect = 2e-65, Method: Composition-based stats. Identities = 87/183 (47%), Positives = 115/183 (62%), Gaps = 4/183 (2%) Query: 44 VGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSP 103 G+ RG T+WLTGLSGAGKTT++ ALE+ L G LDGD +R L K LGFS Sbjct: 17 RGSHMQQRGVTIWLTGLSGAGKTTITHALEKKLRDSGYRLEVLDGDVVRTNLTKGLGFSK 76 Query: 104 EDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLH 163 EDR+ N+RRI V+ L G++ + S ISPY R + F EVFV+APL Sbjct: 77 EDRDTNIRRIGFVSHLLTRNGVIVLVSAISPYAAIRQEVKHTI----GDFLEVFVNAPLA 132 Query: 164 VCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER 223 VCE+RDVKGLY KAR+GEIKGFTGID YE P P++ +TD ++++ V ++ + L + Sbjct: 133 VCEERDVKGLYAKARSGEIKGFTGIDDPYEPPTNPDVECRTDLEELDESVGKIWQKLVDL 192 Query: 224 DIV 226 + Sbjct: 193 KYI 195 >3CR8-A nrPDB Length = 552 Score = 238 bits (607), Expect = 6e-63, Method: Composition-based stats. Identities = 77/177 (43%), Positives = 103/177 (58%), Gaps = 2/177 (1%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL-DGDNIRQGLNKNLGFSPEDREEN 109 +G TV+ TGLSGAGK+T++ AL L+ G C TL DGD +R+ L+ LGFS R+ N Sbjct: 368 QGFTVFFTGLSGAGKSTLARALAARLMEMGGRCVTLLDGDIVRRHLSSELGFSKAHRDVN 427 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRD 169 VRRI VA + I + I+PY Q R + R + E F E+ V P+ CE RD Sbjct: 428 VRRIGFVASEITKNRGIAICAPIAPYRQTRRDVRAMIEAVG-GFVEIHVATPIETCESRD 486 Query: 170 VKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIV 226 KGLY KARAG I FTG+ YE PE PEL + T +++ VQQ++ L+ + Sbjct: 487 RKGLYAKARAGLIPEFTGVSDPYEVPETPELAIDTTGLAIDEAVQQILLKLEHEGYL 543 Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats. Identities = 79/393 (20%), Positives = 135/393 (34%), Gaps = 52/393 (13%) Query: 237 LYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCL 296 L PE K K +A +LP+L ++ +++L G +PL GFM + + L Sbjct: 16 LIDPE-KREALKHEALSLPSLDLDWQQQCELEMLMTGAYSPLTGFMTRAQCARVESAQQL 74 Query: 297 LDGGVINLSVPIVLTATHEDKERLDGCTAFALMY-EGRRVAILRNPEFFEHRKEERCARQ 355 DG PI LT+ AL EG +AIL + ++ Sbjct: 75 DDGSF--WPSPITLTSRDRALADRRPGERLALRDGEGYMLAILTLSDVWK---------- 122 Query: 356 WGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAV 415 + W + G+++ D + R TP EL+ F + Sbjct: 123 ---------------DGERWHLAGEVEGAALPPHPDFV-SLRATPAELRALFVRRGWRRI 166 Query: 416 FAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDV---PLMW-RMKQ 471 A+Q R P+H + + LLLHP G D+ P + ++ Sbjct: 167 IAWQARQPMHRAQYEFCLKSAIE------NEANLLLHPQVG----GDITEAPAYFGLVRS 216 Query: 472 HAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHP- 530 A+ + TT +++ P+P A + G + I G + Sbjct: 217 FLAIRDR--FPAATTQLSLLPAPPPEASGRALLLRAIVARNFGCSLLIAGGEHQPDGGDC 274 Query: 531 ETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEF-ISGT 589 G+DL + V A I + ++ + Y + + +SG Sbjct: 275 RRGEDLTQNRVDPSVAERAE-KIGVRLIAYPRMVYVEDRAEHLPEAEAPQGARLLTLSGE 333 Query: 590 RMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLE 622 ++ R G K PE + P+ VL E ++ Sbjct: 334 EFQRRMRAGLKIPEWYSFPE---VLAELHRQTP 363 >3A4L-A nrPDB Length = 260 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 50/243 (20%), Positives = 97/243 (39%), Gaps = 9/243 (3%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIA 114 + LTGL G GK+T S L + L + I L D IR ++ E EE +++ Sbjct: 7 IILTGLPGVGKSTFSKNLAKILSKNNIDVIVLGSDLIR----ESFPVWKEKYEEFIKKST 62 Query: 115 EVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLY 174 A I + Y R + I + + + +++ A L V +R+++ Sbjct: 63 YRLIDSALKNYWVIVDDTNYYNSMRRDLINIAKKYNKNYAIIYLKASLDVLIRRNIERGE 122 Query: 175 KKARAGEIKGFTGIDSEYEKPE--APELVLKTDS-CDVNDCVQQVVELLQERDIVPVDAS 231 K K + D +K + P L++ T D N+ ++++E +E V Sbjct: 123 KIPNEVIKKMYEKFDEPGKKYKWDEPFLIIDTTKDIDFNEIAKKLIEKSKEIPKFYVLEE 182 Query: 232 YEVKELYVPEN-KLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQC 290 + K + + K +E + + K++K ++ V L + + + M E + + Sbjct: 183 NKNKNNNISDKIDKETRKIVSEYIKSKKLDKDKIKEVVELRKEFLKKIKK-MEEVDADRV 241 Query: 291 LHF 293 L Sbjct: 242 LKE 244 >2P5T-B nrPDB Length = 253 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 22 MQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGI 81 +Q T+ ++ H ++RN R G + + + L G SGAGKTT+ ++ Sbjct: 3 IQDYTDSEFK-HALARNLRSLTRGKKSSKQPIAILLGGQSGAGKTTIHRIKQKEFQ---G 58 Query: 82 PCYTLDGDNIR 92 +DGD+ R Sbjct: 59 NIVIIDGDSFR 69 >1KNQ-A nrPDB Length = 175 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 34/180 (18%), Positives = 67/180 (37%), Gaps = 33/180 (18%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNI--RQGLNKNLGFSP---EDREENVR 111 L G+SG+GK+ V+ + L LDGD + R+ + K P +DR+ ++ Sbjct: 13 LMGVSGSGKSAVASEVAHQL-----HAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQ 67 Query: 112 RIAEVAKLFADAG--LVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRD 169 + + A + + S + + + R + + +++ V E R Sbjct: 68 ALNDAAFAMQRTNKVSLIVCSAL------KKHYRDLLREGNPNLSFIYLKGDFDVIESR- 120 Query: 170 VKGLYKKARAG-------EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQE 222 KAR G + F + E LV+ D + V +E++++ Sbjct: 121 -----LKARKGHFFKTQMLVTQFETLQEP-GADETDVLVVDID-QPLEGVVASTIEVIKK 173 >4EUN-A nrPDB Length = 200 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 4/117 (3%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIA 114 V + G+SG+GKTT++ + + + + + + EDR +R +A Sbjct: 32 VVVMGVSGSGKTTIAHGVADETGLEFAEADAFHSPENIATMQRGIPLTDEDRWPWLRSLA 91 Query: 115 EVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVK 171 E ADAG+ I + + R+ R+ S+ F +D P V + R K Sbjct: 92 EWMDARADAGVSTIITCSALKRTYRDVLRE--GPPSVDFL--HLDGPAEVIKGRMSK 144 >5L3R-A nrPDB Length = 301 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 17/39 (43%), Positives = 19/39 (48%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 + L GL G GKTTV L YL G C + GD R Sbjct: 108 VILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYR 146 >4CVN-A nrPDB Length = 191 Score = 38.1 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 42/177 (23%), Positives = 70/177 (39%), Gaps = 29/177 (16%) Query: 52 GCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR-QGLNKNLGFSPEDREENV 110 G + +TG G GKTT++ L E L G N+R L K G RE + Sbjct: 11 GMLIAITGTPGVGKTTIAKLLAEKL---GYEYV-----NLRDFALEKGCG-----REVD- 56 Query: 111 RRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFV--DAPLHVCEQR 168 EV + + F+ +DRN H +P V V P + E+ Sbjct: 57 ---GEVEVEIDE-----LAYFVEKELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERL 108 Query: 169 DVKGLYKKARAGEIKGFTGIDSEY-EKPEAPE--LVLKTDSCDVNDCVQQVVELLQE 222 +G Y K + GE +D+ E + E + + T + + V++++ L++ Sbjct: 109 RERG-YSKEKIGENVEAELVDAILIEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKS 164 >3E70-C nrPDB Length = 328 Score = 37.4 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 8/81 (9%) Query: 35 VSRNKRGQVVGT-RGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQ 93 + ++R ++ R + + G +G+GKTT L +L HG D R Sbjct: 111 LETSRRIDLIEEIRKAEKPYVIMFVGFNGSGKTTTIAKLANWLKNHGFSVVIAASDTFRA 170 Query: 94 GLNKNLGFSPEDREENVRRIA 114 G + L EE+ +RI Sbjct: 171 GAIEQL-------EEHAKRIG 184 >1KAG-A nrPDB Length = 173 Score = 37.0 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 62/175 (35%), Gaps = 14/175 (8%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDN---IRQGLNKNLGFSPEDREENVR 111 ++L G GAGK+T+ L + L D D R G + F E E Sbjct: 7 IFLVGPMGAGKSTIGRQLAQQLNMEFY-----DSDQEIEKRTGADVGWVFDLEGEEGFRD 61 Query: 112 RIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVK 171 R +V + + + + + R ++ + + E ++ L ++ + Sbjct: 62 REEKVINELTEKQGIVLATG-GGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKR 120 Query: 172 GLY--KKARAGEIKGFTGIDSE-YEKPEAPELVLKTDSCDVNDCVQQVVELLQER 223 L + ++ + YE E ++ ++TD Q++ +L+ Sbjct: 121 PLLHVETPPREVLEALANERNPLYE--EIADVTIRTDDQSAKVVANQIIHMLESN 173 >3B5X-A nrPDB Length = 582 Score = 36.6 bits (83), Expect = 0.031, Method: Composition-based stats. Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 28/115 (24%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEE-YLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREEN 109 +G TV L G SG+GK+T++ Y V G C LDG ++R + + N Sbjct: 368 QGKTVALVGRSGSGKSTIANLFTRFYDVDSGSIC--LDGHDVR-----------DYKLTN 414 Query: 110 VRR----IAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGA-----SLPFFE 155 +RR +++ LF D I + I+ Y + R+ E A ++ F E Sbjct: 415 LRRHFALVSQNVHLFNDT----IANNIA-YAAEGEYTREQIEQAARQAHAMEFIE 464 >6CUM-A nrPDB Length = 315 Score = 36.2 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 25/55 (45%) Query: 35 VSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 V ++RG+V+ G + +TG GAGK+T A+ G+ L D Sbjct: 51 VESDRRGEVLAALGPATPRVIGVTGPPGAGKSTTVGAMVGAYRERGLRVAVLAVD 105 >1G3Q-A nrPDB Length = 237 Score = 35.1 bits (79), Expect = 0.097, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 22/49 (44%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPED 105 ++G G GKTTV+ L L G +DGD L+ LG D Sbjct: 8 VSGKGGTGKTTVTANLSVALGDRGRKVLAVDGDLTMANLSLVLGVDDPD 56 >2V3C-C nrPDB Length = 432 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 19/39 (48%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 + L G+ G+GKTT + L Y+ G+ + D R Sbjct: 101 VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYR 139 >5L3R-B nrPDB Length = 293 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 37 RNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLN 96 +N + ++ G + + + G++G GKTT L L G GD R + Sbjct: 78 KNSKTEL--QLGFRKPAVIMIVGVNGGGKTTSLGKLAHRLKNEGTKVLMAAGDTFRAAAS 135 Query: 97 KNL 99 L Sbjct: 136 DQL 138 >2OG2-A nrPDB Length = 359 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 37 RNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLN 96 +N + ++ G + + + G++G GKTT L L G GD R + Sbjct: 144 KNSKTEL--QLGFRKPAVIMIVGVNGGGKTTSLGKLAHRLKNEGTKVLMAAGDTFRAAAS 201 Query: 97 KNL 99 L Sbjct: 202 DQL 204 >2I3B-A nrPDB Length = 189 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFS 102 V+LTG G GKTT+ E L G+P + +RQG + +GF Sbjct: 4 VFLTGPPGVGKTTLIHKASEVLKSSGVPVDGFYTEEVRQG-GRRIGFD 50 >4D4L-A nrPDB Length = 449 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 40/185 (21%), Positives = 68/185 (36%), Gaps = 22/185 (11%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLD-GDNIRQGLN--KNLGFSPEDREENV 110 + + GL GKT +S L YL G+P + G+ R+ + + F D EE + Sbjct: 37 VIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAM 96 Query: 111 R--------RIAEVAKLFADAGL-VCITSFISPYTQDRNNARQIHEGASLP--FFEVFVD 159 + + +V A G + + + + R+ + F E D Sbjct: 97 KVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCD 156 Query: 160 APLHVC----EQRDVKGLYKKARAGE-IKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQ 214 P V E + YK + E + F S YE P L D CD + + Sbjct: 157 DPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQP---LDPDKCDRDLSLI 213 Query: 215 QVVEL 219 +V+++ Sbjct: 214 KVIDV 218 >3TRF-A nrPDB Length = 185 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 39/175 (22%), Positives = 67/175 (38%), Gaps = 25/175 (14%) Query: 55 VWLTGLSGAGKTTVSMALEEY----LVCHGIPCYTLDGDNIR--QGLNKNLGFSPEDRE- 107 ++L GL GAGKT+V L + L G +I + GF +RE Sbjct: 8 IYLIGLMGAGKTSVGSQLAKLTKRILYDSDKEIEKRTGADIAWIFEMEGEAGFRRREREM 67 Query: 108 -ENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCE 166 E + ++ + + A G V + D N +QI E + + +D L Sbjct: 68 IEALCKLDNI--ILATGGGVVL---------DEKNRQQISETGVVIYLTASIDTQLKRIG 116 Query: 167 QRD--VKGLYKKARAGE-IKGFTGIDSE-YEKPEAPELVLKTDSCDVNDCVQQVV 217 Q+ + L+ K + E ++ I Y+ +LV TD + Q++ Sbjct: 117 QKGEMRRPLFIKNNSKEKLQQLNEIRKPLYQA--MADLVYPTDDLNPRQLATQIL 169 >3TK1-A nrPDB Length = 330 Score = 34.3 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 8/99 (8%) Query: 4 PGSLCKKVKLSNNAQNWG----MQRATNVTYQAHHVSRNKRGQVVGT--RGGFRGCTVWL 57 PGS+ + VK A G + RA + R + +++ R V + Sbjct: 2 PGSMTQTVKDLAAAIRSGDRAALPRAITLVESTRADHRERAQELLLELMPDAGRAMHVGI 61 Query: 58 TGLSGAGKTTVSMALEEYLVCHGIPCYTL--DGDNIRQG 94 TG+ G GK+T AL +L+ G L D ++R G Sbjct: 62 TGVPGVGKSTSIEALGMHLIEQGHRVAVLAVDPSSVRSG 100 >2PT5-A nrPDB Length = 168 Score = 34.3 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 32/172 (18%), Positives = 68/172 (39%), Gaps = 9/172 (5%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDN-IRQGLNKNLGFSPEDREENVRRI 113 ++L G +GK+TV L L IP Y +D + R+GL+ F + + Sbjct: 3 IYLIGFMCSGKSTVGSLLSRSLN---IPFYDVDEEVQKREGLSIPQIFEKKGEAYFRKLE 59 Query: 114 AEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGL 173 EV K ++ V I++ + + + F ++ + L C+ + L Sbjct: 60 FEVLKDLSEKENVVISTG-GGLGANEEALNFMKSRGTTVFIDIPFEVFLERCKDSKERPL 118 Query: 174 YKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDI 225 K+ EIK + + ++ +K + + V++++ L+ + Sbjct: 119 LKRPLD-EIKNL--FEERRKIYSKADIKVKGEK-PPEEVVKEILLSLEGNAL 166 >1VIA-A nrPDB Length = 175 Score = 33.9 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 8/79 (10%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD-NIRQGLNKNLGFSPEDREENVRRI 113 + G G+GK+T++ AL + L LD D I Q N+ + E + EN R Sbjct: 7 IVFIGFMGSGKSTLARALAKDL-----DLVFLDSDFLIEQKFNQKVSEIFEQKRENFFRE 61 Query: 114 AE--VAKLFADAGLVCITS 130 E +A F+ CI + Sbjct: 62 QEQKMADFFSSCEKACIAT 80 >2DWP-A nrPDB Length = 520 Score = 33.9 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 40/185 (21%), Positives = 68/185 (36%), Gaps = 22/185 (11%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLD-GDNIRQGLN--KNLGFSPEDREENV 110 + + GL GKT +S L YL G+P + G+ R+ + + F D EE + Sbjct: 37 VIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAM 96 Query: 111 R--------RIAEVAKLFADAGL-VCITSFISPYTQDRNNARQIHEGASLP--FFEVFVD 159 + + +V A G + + + + R+ + F E D Sbjct: 97 KVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCD 156 Query: 160 APLHVC----EQRDVKGLYKKARAGE-IKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQ 214 P V E + YK + E + F S YE P L D CD + + Sbjct: 157 DPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQP---LDPDKCDRDLSLI 213 Query: 215 QVVEL 219 +V+++ Sbjct: 214 KVIDV 218 >1ION-A nrPDB Length = 243 Score = 33.9 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 16/44 (36%), Positives = 21/44 (47%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLG 100 ++G G GKTTV+ L L G +DGD L+ LG Sbjct: 8 VSGKGGTGKTTVTANLSVALGEMGRKVLAVDGDLTMANLSLVLG 51 >6FRK-x nrPDB Length = 504 Score = 33.5 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 25/77 (32%), Gaps = 6/77 (7%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRI 113 + GL G+GKTT L Y G + D R G F + RI Sbjct: 103 VIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAG-----AFDQLKQNATKARI 157 Query: 114 AEVAKLFADAGLVCITS 130 + + V I S Sbjct: 158 PFYGS-YTEMDPVIIAS 173 >5L3Q-A nrPDB Length = 442 Score = 33.5 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 25/77 (32%), Gaps = 6/77 (7%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRI 113 + GL G+GKTT L Y G + D R G F + RI Sbjct: 109 VIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAG-----AFDQLKQNATKARI 163 Query: 114 AEVAKLFADAGLVCITS 130 + + V I S Sbjct: 164 PFYGS-YTEMDPVIIAS 179 >3JAJ-z nrPDB Length = 426 Score = 33.5 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 25/77 (32%), Gaps = 6/77 (7%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRI 113 + GL G+GKTT L Y G + D R G F + RI Sbjct: 100 VIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAG-----AFDQLKQNATKARI 154 Query: 114 AEVAKLFADAGLVCITS 130 + + V I S Sbjct: 155 PFYGS-YTEMDPVIIAS 170 >1A7J-A nrPDB Length = 290 Score = 33.5 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRR 112 + +TG SGAG +TV ++ G+ +++GD + F+ D + + R Sbjct: 8 ISVTGSSGAGTSTVKHTFDQIFRREGVKAVSIEGDAFHR-------FNRADMKAELDR 58 >4Y0A-A nrPDB Length = 179 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 64/183 (34%), Gaps = 25/183 (13%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLG------FSPEDREE 108 ++L G GAGKTTV L E L LD D + + G F E Sbjct: 11 IYLVGPMGAGKTTVGRHLAELLGR-----EFLDSD---HEIERKTGATIPWIFEKEGEVG 62 Query: 109 NVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQR 168 R V + + + TQ N R+ + + V++ P+ + QR Sbjct: 63 FRTRETVVLNELTSRKALVLATGGGAITQAPN--REFLKQRGI---VVYLYTPVELQLQR 117 Query: 169 DVKG-----LYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER 223 + L + +++ I + E ++T+ D Q++++L+ Sbjct: 118 TYRDKNRPLLQVENPEQKLRDLLKIRDPLYR-EVAHYTIETNQGAARDLAQKILQLILSN 176 Query: 224 DIV 226 + Sbjct: 177 KLK 179 >2WWW-A nrPDB Length = 349 Score = 33.1 bits (74), Expect = 0.32, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 19/50 (38%) Query: 40 RGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 R Q +G V L+G GAGK+T + L G L D Sbjct: 62 REQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVD 111 >3T61-A nrPDB Length = 202 Score = 33.1 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 21/168 (12%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDG----DNIRQGLNKNLGFSPEDREEN 109 ++ + G+SG+GK++V A+ E G P D +NIR+ +++ + + +DR Sbjct: 20 SIVVMGVSGSGKSSVGEAIAE---ACGYPFIEGDALHPPENIRK-MSEGIPLTDDDRWPW 75 Query: 110 VRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRD 169 + I E +L + +V S + R+ R E A VF+ V +R Sbjct: 76 LAAIGE--RLASREPVVVSCSALK--RSYRDKLR---ESAPGGLAFVFLHGSESVLAER- 127 Query: 170 VKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVV 217 R G + + ++ E E P ++T + DV + ++V Sbjct: 128 -----MHHRTGHFMPSSLLQTQLETLEDPRGEVRTVAVDVAQPLAEIV 170 >3MD0-A nrPDB Length = 355 Score = 32.7 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL--DGDNIRQG 94 V +TG+ G GK+T AL +L+ G L D + R G Sbjct: 82 VGITGVPGVGKSTAIEALGMHLIERGHRVAVLAVDPSSTRTG 123 >3VAA-A nrPDB Length = 199 Score = 32.7 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 55 VWLTGLSGAGKTTVSMALEEYLV 77 ++LTG GAGKTT+ A L Sbjct: 28 IFLTGYMGAGKTTLGKAFARKLN 50 >4JMP-A nrPDB Length = 269 Score = 32.7 bits (73), Expect = 0.48, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 14/29 (48%) Query: 61 SGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 GAGK+T++ L G +DGD Sbjct: 90 PGAGKSTIAANLAVAYAQAGYKTLIVDGD 118 >5MKK-B nrPDB Length = 577 Score = 32.7 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 28/62 (45%), Gaps = 1/62 (1%) Query: 25 ATNVTYQAHHVSRNKRGQVVG-TRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPC 83 + V ++ + R+ R + G T G T+ +TG +G+GK+ ++ + L Sbjct: 335 SGEVRFEGVGLKRDGRWLLRGLTLTIPEGMTLGITGRTGSGKSLLAALVPRLLDPSEGRV 394 Query: 84 YT 85 Y Sbjct: 395 YV 396 >3PXU-A nrPDB Length = 170 Score = 32.7 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 39/101 (38%), Gaps = 9/101 (8%) Query: 527 MPHPETGKDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYN----KKKKRMDYYDSEHHED 582 M KD + ++ + E F++A N + M + Sbjct: 71 MGFTGLLKDFVRANDARVIVRGLRAVSDFE-YEFQMAGMNRYLLPDVETMFM---TPSDQ 126 Query: 583 FEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEK 623 ++FISGT +R++A+ G F+ P LTE ++ + Sbjct: 127 YQFISGTIVREIAQLGGDV-SKFVFPSVEKWLTEKVAAMAQ 166 >3UX8-A nrPDB Length = 670 Score = 32.7 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYT 85 RG V LTGLSG+GK++++ + + G Y Sbjct: 43 RGKLVVLTGLSGSGKSSLAF---DTIYAEGQRRYV 74 >2R6F-A nrPDB Length = 972 Score = 32.7 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Query: 51 RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYT 85 RG V LTGLSG+GK++++ + + G Y Sbjct: 43 RGKLVVLTGLSGSGKSSLAF---DTIYAEGQRRYV 74 >5OCH-A nrPDB Length = 612 Score = 32.4 bits (72), Expect = 0.55, Method: Composition-based stats. Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 52 GCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQ 93 G V L G SG GKTTV+ LE + LDG ++R Sbjct: 391 GKIVALVGQSGGGKTTVASLLERFYDPTAG-VVMLDGRDLRT 431 >3C8U-A nrPDB Length = 208 Score = 32.4 bits (72), Expect = 0.61, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 19/35 (54%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 V L+G G+GK+T+S L L G+P + D Sbjct: 25 VALSGAPGSGKSTLSNPLAAALSAQGLPAEVVPMD 59 >4XRP-A nrPDB Length = 312 Score = 32.4 bits (72), Expect = 0.61, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSP--EDREENVRRIA 114 L G G+GK+T + Y + ++ D+ R + SP E+R + + Sbjct: 16 LVGAPGSGKSTFAR----YFIRTEDNWVRVNRDDFRLMQFGDSLMSPFYEERITKMVEAS 71 Query: 115 EVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQR 168 +A L ++ I + S ++ E A + F +VF D P+ +R Sbjct: 72 VIALLKNRTNVI-IDATNSSLRSLQDMVHTYTEYADISF-KVF-DLPVEELVKR 122 >4AK9-A nrPDB Length = 318 Score = 32.4 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 20/54 (37%) Query: 46 TRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNL 99 G R + + G++G GKTT L G+ GD R + L Sbjct: 110 QLGNSRPAVLMIVGVNGGGKTTTLGKLANRFKKEGVKVLMAAGDTFRAAAGEQL 163 >5L3S-A nrPDB Length = 298 Score = 32.4 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 17/40 (42%) Query: 53 CTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 + L G+ G+GKTT + L + G + D R Sbjct: 103 FIIMLVGVQGSGKTTTAGKLAYFYKKRGYKVGLVAADVYR 142 >5DGX-A nrPDB Length = 256 Score = 32.4 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 9/53 (16%) Query: 52 GCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDG--------DNIRQGLN 96 G TV G SG+GKTT++ + + H LDG +N+R L+ Sbjct: 44 GQTVAFVGKSGSGKTTLTSIISRFYTQHEGEI-LLDGVDTRELTLENLRSHLS 95 >4CVK-A nrPDB Length = 475 Score = 32.4 bits (72), Expect = 0.71, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 36/98 (36%), Gaps = 17/98 (17%) Query: 47 RGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLG------ 100 R F G +TG +GKTTV L L ++ R LN +LG Sbjct: 97 RRKFTGPLAAMTG--SSGKTTVKEMLASILRTQAGDAESVLA--TRGNLNNDLGVPLTLL 152 Query: 101 -FSPEDREENVR----RIAEVAK--LFADAGLVCITSF 131 +P+ R + RI E+A + IT+ Sbjct: 153 QLAPQHRSAVIELGASRIGEIAYTVELTRPHVAIITNA 190 >1QZX-A nrPDB Length = 440 Score = 32.0 bits (71), Expect = 0.75, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 17/40 (42%) Query: 53 CTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 + L G+ G+GKTT + L + G + D R Sbjct: 105 FIIMLVGVQGSGKTTTAGKLAYFYKKRGYKVGLVAADVYR 144 >4OQS-A nrPDB Length = 433 Score = 32.0 bits (71), Expect = 0.76, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 61/154 (39%), Gaps = 14/154 (9%) Query: 259 INKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKE 318 + K+ +++A +P + + + L D + N+++ ++L A HE Sbjct: 193 LGKLTRYIAELVATKRLSPKDDLLG-----SLITDTDLTDEELTNIAL-LLLVAGHETTA 246 Query: 319 RLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIG 378 + G FAL+ ++A L +P+ E GT N ++ V +G + Sbjct: 247 NMLGLGTFALLQHPEQIAALDSPDAVEELLRYLSIVHLGT--PNRAALEDVELEGQMIRK 304 Query: 379 GD-----LQVLDR-VYWNDGLDQYRLTPTELKQK 406 GD L ++R D D +L + ++ Sbjct: 305 GDTVAIGLPAVNRDPKVFDEPDILQLDRVDARKH 338 >4G1U-C nrPDB Length = 266 Score = 32.0 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 9/100 (9%) Query: 52 GCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVR 111 G V + G +GAGK+T+ L YL C+ L G N+ K L + +R Sbjct: 37 GEMVAIIGPNGAGKSTLLRLLTGYLSPSHGECHLL-GQNLNSWQPKALARTRAV----MR 91 Query: 112 RIAEVAKLFADAGLVCITSFISPY--TQDRNNARQIHEGA 149 + +E+A F+ + ++ + +PY +QDR +Q+ Sbjct: 92 QYSELAFPFSVSEVIQMGR--APYGGSQDRQALQQVMAQT 129 >1IHU-A nrPDB Length = 589 Score = 32.0 bits (71), Expect = 0.80, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD---NIRQGLNKNLG 100 ++ TG G GKT++S A L G + D N+ Q ++ +G Sbjct: 11 LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIG 59 >5HTK-A nrPDB Length = 505 Score = 32.0 bits (71), Expect = 0.81, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 45/121 (37%), Gaps = 14/121 (11%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGL---NKNLGFSPEDREENV- 110 + + GL GKT VS L YL G+P + R+ K+ F D EE + Sbjct: 41 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMK 100 Query: 111 --RRIAEVAK------LFADAGLVCITSFISPYTQDRNNARQIHEGASLP--FFEVFVDA 160 ++ A VA L + G + + + + R+ E S F E D Sbjct: 101 IRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDD 160 Query: 161 P 161 P Sbjct: 161 P 161 >1RZ3-A nrPDB Length = 201 Score = 32.0 bits (71), Expect = 0.88, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 16/31 (51%) Query: 59 GLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 GLS +GKTT++ L + L GI D Sbjct: 29 GLSRSGKTTLANQLSQTLREQGISVCVFHMD 59 >4OQR-A nrPDB Length = 457 Score = 32.0 bits (71), Expect = 0.91, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 61/154 (39%), Gaps = 14/154 (9%) Query: 259 INKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKE 318 + K+ +++A +P + + + L D + N+++ I+L A HE Sbjct: 232 LGKLTRYIAELVATKRLSPKDDLLG-----SLITDTDLTDEELTNIAL-ILLVAGHETTA 285 Query: 319 RLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIG 378 + G FAL+ ++A L +P+ E GT N ++ V +G + Sbjct: 286 NMLGLGTFALLQHPEQIANLDSPDAVEELLRYLSIVHLGT--PNRAALEDVELEGQMIRK 343 Query: 379 GD-----LQVLDR-VYWNDGLDQYRLTPTELKQK 406 GD L ++R D D +L + ++ Sbjct: 344 GDTVAIGLPAVNRDPKVFDEPDILQLDRVDARKH 377 >3DM5-A nrPDB Length = 443 Score = 31.6 bits (70), Expect = 0.99, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 16/38 (42%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQG 94 + G+ G+GKTT L Y G + D R G Sbjct: 105 MVGIQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPG 142 >5EG1-A nrPDB Length = 580 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 22 MQRATNVTYQAHHVSRNKRGQVVGTRGG--FRGCTVWLTGLSGAGKTTVSMALEEYLVCH 79 M+R N++ + S + +++ + F G LTG SG+GK+T+ + Y + Sbjct: 339 MERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNY 398 Query: 80 GIPCYTLD 87 Y D Sbjct: 399 FGDIYLND 406 >2F6R-A nrPDB Length = 281 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 21/37 (56%), Gaps = 6/37 (16%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQ 93 LTG+SG+GK++V+ L + Y +D D++ Sbjct: 80 LTGISGSGKSSVAQRL------KNLGAYIIDSDHLGH 110 >2PH1-A nrPDB Length = 262 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 21/53 (39%) Query: 37 RNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 R ++ G + ++G G GK+TV+ L + G LD D Sbjct: 4 RVTDEEIKERLGKIKSRIAVMSGKGGVGKSTVTALLAVHYARQGKKVGILDAD 56 >3NXS-A nrPDB Length = 329 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL--DGDNIRQG 94 V +TG+ G GK+T AL +L+ G L D + R G Sbjct: 60 VGITGVPGVGKSTTIEALGMHLIEAGHRVAVLAVDPSSTRTG 101 >2IY3-A nrPDB Length = 432 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 17/37 (45%) Query: 56 WLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 +L GL G+GKTT + L Y G + D R Sbjct: 102 FLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQR 138 >1WDT-A nrPDB Length = 665 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 10/126 (7%) Query: 44 VGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSP 103 +GT GG TV L G +G+GKTT++ AL +G ++P Sbjct: 1 MGTEGGAMIRTVALVGHAGSGKTTLTEALLYKTGAKERRGRVEEG-------TTTTDYTP 53 Query: 104 EDR-EENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPL 162 E + R LF + + + Y R E A V +A + Sbjct: 54 EAKLHRTTVRTGVAPLLFRGHRVFLLDAP--GYGDFVGEIRGALEAADAALVAVSAEAGV 111 Query: 163 HVCEQR 168 V +R Sbjct: 112 QVGTER 117 >1RJ9-B nrPDB Length = 300 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 17/37 (45%) Query: 56 WLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 +L GL G+GKTT + L Y G + D R Sbjct: 102 FLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQR 138 >2FFH-A nrPDB Length = 425 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 17/37 (45%) Query: 56 WLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIR 92 +L GL G+GKTT + L Y G + D R Sbjct: 102 FLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQR 138 >5HCI-A nrPDB Length = 261 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 41/108 (37%), Gaps = 4/108 (3%) Query: 54 TVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRI 113 T+ G++G+GKTT L +L P Y ++ D + D + +++ Sbjct: 4 TIICIGMAGSGKTTFMQRLNSHLRAEKTPPYVINLDPAVLRVPYGANIDIRDSIK-YKKV 62 Query: 114 AEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAP 161 E G + + ++ ++ + ++ E F +D P Sbjct: 63 ME-NYQLGPNGAIVTS--LNLFSTKIDQVIRLVEQKKDKFQNCIIDTP 107 >2IYT-A nrPDB Length = 184 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNI---RQGLNKNLGFSPEDREENVRRI 113 L GL G+GK+T+ L + L LD D R G + F+ D E+ RRI Sbjct: 7 LVGLPGSGKSTIGRRLAKAL-----GVGLLDTDVAIEQRTGRSIADIFA-TDGEQEFRRI 60 Query: 114 AE--VAKLFADAGLV 126 E V AD V Sbjct: 61 EEDVVRAALADHDGV 75 >5HR5-A nrPDB Length = 531 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 14/121 (11%) Query: 55 VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLD-GDNIRQGLN--KNLGFSPEDREENV- 110 + + GL GKT VS L YL G+P + G RQ + K+ F D EE + Sbjct: 42 IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMK 101 Query: 111 --RRIAEVAK------LFADAGLVCITSFISPYTQDRNNARQIHEGASLP--FFEVFVDA 160 ++ A VA L ++G + + + + R+ E S F E D Sbjct: 102 IRKQCALVALKDVKAYLTEESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDD 161 Query: 161 P 161 P Sbjct: 162 P 162 >3HJS-A nrPDB Length = 280 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 49/136 (36%), Gaps = 12/136 (8%) Query: 103 PEDREENVRRIAEVAK--LFADAGLVCITSFISP-YTQDRNNARQIHEGASLP-FFEVFV 158 + + R+A +AK L A ++ P Y + + EG P F +VF+ Sbjct: 24 RATADTSPERLAAIAKDALGALNDVILKHGVTYPEYRVFKQWLIDVGEGGEWPLFLDVFI 83 Query: 159 DAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCV--QQV 216 + + R KG G I+G I++ E P L ++ + + V QV Sbjct: 84 EHSVEEVLARSRKG-----TMGSIEGPYYIENSPELPSKCTLPMREEDEKITPLVFSGQV 138 Query: 217 VELLQERDIVPVDASY 232 + L + Sbjct: 139 TD-LDGNGLAGAKVEL 153 >5X7J-A nrPDB Length = 198 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 17/34 (50%) Query: 50 FRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPC 83 G + L GL G+GKTT + L +L G P Sbjct: 1 MPGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPV 34 >4JYC-A nrPDB Length = 337 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 4/63 (6%) Query: 34 HVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL--DGDNI 91 R+ V+ G R V +TG+ G GK+T AL L G L D + Sbjct: 39 AAVRDLIDAVLPQTG--RAIRVGITGVPGVGKSTTIDALGSLLTAAGHKVAVLAVDPSST 96 Query: 92 RQG 94 R G Sbjct: 97 RTG 99 >5EUM-A nrPDB Length = 258 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 16/108 (14%) Query: 52 GCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVR 111 G TV L G SG+GK+T++ + + LDG NI+ NL EN Sbjct: 45 GKTVALVGRSGSGKSTIANLVTRFYDIEQGEI-LLDGVNIQDYRLSNL-------RENCA 96 Query: 112 RIAEVAKLFADAGLVCITSFISPYTQDRNNARQIH----EGASLPFFE 155 +++ LF D I + I+ QD+ + +I +L F E Sbjct: 97 VVSQQVHLFNDT----IANNIAYAAQDKYSREEIIAAAKAAYALEFIE 140 >4X4R-A nrPDB Length = 457 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 40/98 (40%), Gaps = 12/98 (12%) Query: 141 NARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPEL 200 R+ E SL FF+ PL + +R K + ++ A F P++ Sbjct: 241 LCREFMEAPSLGFFK--PKHPLEIEPERLRKIVEERGTAVFAVKF----------RKPDI 288 Query: 201 VLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELY 238 V + +++ E L+ + +P+ ++++ E + Sbjct: 289 VDDNLYPQLERASRKIFEFLERENFMPLRSAFKASEEF 326 >5AUQ-A nrPDB Length = 248 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKN--LGFSPED 105 ++G G GK+ VS L L G LD D G + + LGF P++ Sbjct: 25 VSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDF--HGASDHVILGFEPKE 73 >2IXE-A nrPDB Length = 271 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 50 FRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 + G L G +G+GK+TV+ L+ G LDG+ Sbjct: 43 YPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKV-LLDGE 81 >1ZU4-A nrPDB Length = 320 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 27/71 (38%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEV 116 L G++G GKTT + Y G D R G + L + R N + + Sbjct: 110 LVGVNGTGKTTSLAKMANYYAELGYKVLIAAADTFRAGATQQLEEWIKTRLNNKVDLVKA 169 Query: 117 AKLFADAGLVC 127 KL AD V Sbjct: 170 NKLNADPASVV 180 >4JLV-A nrPDB Length = 269 Score = 30.0 bits (66), Expect = 2.9, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 13/29 (44%) Query: 61 SGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 GAGK+TV + G +DGD Sbjct: 92 PGAGKSTVVSNVAITYAQAGYKTLVIDGD 120 >6G2G-A nrPDB Length = 310 Score = 30.0 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 16/33 (48%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 L+G G GK++V+ L L G LD D Sbjct: 13 LSGKGGVGKSSVTTQLALSLSQAGYSVGVLDVD 45 >3KB1-A nrPDB Length = 262 Score = 29.7 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 57 LTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD 89 ++G G GK+TV+ L + G LD D Sbjct: 24 MSGKGGVGKSTVTALLAVHYAKQGKKVGILDAD 56 >5XF8-3 nrPDB Length = 997 Score = 29.7 bits (65), Expect = 4.3, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Query: 96 NKNLGFSPE---DREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLP 152 + +G + DRE RR+ A + AD G+VCI F DR ++ E ++ Sbjct: 463 SSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVT 522 Query: 153 FFEVFVDAPLH 163 + + L+ Sbjct: 523 IAKAGIHTTLN 533 >3X1M-A nrPDB Length = 159 Score = 29.3 bits (64), Expect = 5.8, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 578 EHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYK 619 E + FIS T +R++A G F+ P L E +K Sbjct: 118 TPSEKYSFISSTLVREIAALGGDI-SKFVHPAVADALAERFK 158 >3LD9-A nrPDB Length = 223 Score = 28.9 bits (63), Expect = 7.2, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 17/38 (44%) Query: 41 GQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVC 78 G + G + G+ G+GKTT S L EYL Sbjct: 10 GTLEAQTQGPGSMFITFEGIDGSGKTTQSHLLAEYLSE 47 >5CA0-F nrPDB Length = 384 Score = 28.9 bits (63), Expect = 7.5, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 113 IAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKG 172 ++E F ++ ++ T+ +P +N R + EVF+ A E R+ Sbjct: 87 LSESCTWFPESYVIYPTNLKTPVAPAQNGIRHLINNTRTDEREVFLAAYNRRREGREGNV 146 Query: 173 LYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASY 232 K+ AG K + ++ ++++ + E+ V V Y Sbjct: 147 WIAKSSAG---------------------AKGEGILISSEASELLDFIDEQGQVHVIQKY 185 Query: 233 EVKELYVPENKL 244 K L + Sbjct: 186 LEKPLLLEPGHR 197 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.133 0.357 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,327,481 Number of Sequences: 36641 Number of extensions: 979508 Number of successful extensions: 3161 Number of sequences better than 10.0: 104 Number of HSP's better than 10.0 without gapping: 98 Number of HSP's successfully gapped in prelim test: 52 Number of HSP's that attempted gapping in prelim test: 2942 Number of HSP's gapped (non-prelim): 164 length of query: 624 length of database: 10,336,785 effective HSP length: 103 effective length of query: 521 effective length of database: 6,562,762 effective search space: 3419199002 effective search space used: 3419199002 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.5 bits)