BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O35864 (334 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4D10-E nrPDB 699 0.0 4F7O-A nrPDB 543 e-155 5L4K-V nrPDB 141 3e-34 5MPD-V nrPDB 137 9e-33 4O8Y-B nrPDB 135 2e-32 6FJU-A nrPDB 70 1e-12 5CW6-A nrPDB 64 1e-10 3JCO-U nrPDB 51 6e-07 6FVW-U nrPDB 51 8e-07 5CW3-A nrPDB 48 6e-06 5VFQ-Z nrPDB 44 1e-04 6MSD-Z nrPDB 44 1e-04 4R14-A nrPDB 35 0.035 4D18-F nrPDB 34 0.082 5A5T-F nrPDB 33 0.13 3J8B-F nrPDB 33 0.14 5CYV-A nrPDB 31 0.68 5D9W-A nrPDB 29 2.2 1KKH-A nrPDB 29 2.3 5W6G-A nrPDB 29 2.7 4IIC-A nrPDB 29 3.3 1IHM-A nrPDB 28 4.5 3TEB-A nrPDB 28 4.6 4KIT-C nrPDB 28 5.7 3VRD-B nrPDB 28 6.3 1Z69-A nrPDB 28 7.3 5LOL-A nrPDB 27 9.5 >4D10-E nrPDB Length = 334 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/334 (99%), Positives = 334/334 (100%) Query: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL Sbjct: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 Query: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY Sbjct: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 Query: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK Sbjct: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 Query: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL Sbjct: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 Query: 241 LWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKL 300 LWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKL Sbjct: 241 LWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKL 300 Query: 301 AKATRDSCKTTIEAIHGLMSQVIKDKLFNQINVA 334 AKATRDSCKTTIEAIHGLMSQVIKDKLFNQIN++ Sbjct: 301 AKATRDSCKTTIEAIHGLMSQVIKDKLFNQINIS 334 >4F7O-A nrPDB Length = 257 Score = 543 bits (1399), Expect = e-155, Method: Compositional matrix adjust. Identities = 257/257 (100%), Positives = 257/257 (100%) Query: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL Sbjct: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 Query: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY Sbjct: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 Query: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK Sbjct: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 Query: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL Sbjct: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 Query: 241 LWNKYWVNTLSSSSLLT 257 LWNKYWVNTLSSSSLLT Sbjct: 241 LWNKYWVNTLSSSSLLT 257 >5L4K-V nrPDB Length = 310 Score = 141 bits (356), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 80/202 (39%), Positives = 118/202 (58%), Gaps = 11/202 (5%) Query: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 33 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQ 92 Query: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 A ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+DP ++ Sbjct: 93 --AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQS 150 Query: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229 + GKV + AFR P + T L + + + YY++ ++Y Sbjct: 151 VK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSITINYR 208 Query: 230 KSSLDRKLLELLWNKYWVNTLS 251 K+ L++K+L L K W+ L+ Sbjct: 209 KNELEQKMLLNLHKKSWMEGLT 230 >5MPD-V nrPDB Length = 306 Score = 137 bits (344), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 81/197 (41%), Positives = 118/197 (59%), Gaps = 11/197 (5%) Query: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 29 ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQ 88 Query: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP ++ Sbjct: 89 --AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 146 Query: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNK--IEDFGVHC--KQYYALEVSYF 229 + GKV + AFR G + P + T LNK I+ +H + YY+L + Y Sbjct: 147 VK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQAL-IHGLNRHYYSLNIDYH 204 Query: 230 KSSLDRKLLELLWNKYW 246 K++ + K+L L + W Sbjct: 205 KTAKETKMLMNLHKEQW 221 >4O8Y-B nrPDB Length = 240 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 81/197 (41%), Positives = 118/197 (59%), Gaps = 11/197 (5%) Query: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 30 ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQ 89 Query: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP ++ Sbjct: 90 --AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 147 Query: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNK--IEDFGVHC--KQYYALEVSYF 229 + GKV + AFR G + P + T LNK I+ +H + YY+L + Y Sbjct: 148 VK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQAL-IHGLNRHYYSLNIDYH 205 Query: 230 KSSLDRKLLELLWNKYW 246 K++ + K+L L + W Sbjct: 206 KTAKETKMLMNLHKEQW 222 >6FJU-A nrPDB Length = 228 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 51/146 (34%), Positives = 70/146 (47%), Gaps = 11/146 (7%) Query: 46 TKDHHYFK---YCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEG 102 T ++ YF+ +I LAL K+V HA S EV GL++GK G+ + I D+ G Sbjct: 17 TTENLYFQGHMRVRIYPLALAKVVKHAASSLQREVAGLLVGKSAGKVLEIWDAVTGEQYG 76 Query: 103 TETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQ 162 T V MA E + + +GWYHSHPG +LS D+ TQ Q Sbjct: 77 TPAYVQLDEMV---MAKVAEELSKSDKNLYIVGWYHSHPGLDVFLSPTDIDTQKRYQAMF 133 Query: 163 EPFVAVVIDP-----TRTISAGKVNL 183 VA+V+DP TR IS+ K + Sbjct: 134 SKAVALVVDPVDYAKTRRISSLKFKV 159 >5CW6-A nrPDB Length = 262 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 3/112 (2%) Query: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 A L + HA S EVMGL +G+VD ++ + S + + + + + + AA Sbjct: 14 AFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPEQLSAAS 73 Query: 121 IEN---AKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVV 169 E A+ GR +GWYHSHP W S +DV TQ + Q + FV ++ Sbjct: 74 TEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLI 125 >3JCO-U nrPDB Length = 338 Score = 51.2 bits (121), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 57 ISALALLKMVMH---ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAA 113 I+ L LL + H ++ N +G++LG + T+ + +SFALP E E + Sbjct: 10 IAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDVWFLD 69 Query: 114 YEYMAAYIENAKQVGRLENAIGWYHSHP 141 + Y+ E K++ E IGWYHS P Sbjct: 70 HNYIENMNEMCKKINAKEKLIGWYHSGP 97 >6FVW-U nrPDB Length = 304 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 57 ISALALLKMVMH---ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAA 113 I+ L LL + H ++ N +G++LG + T+ + +SFALP E E + Sbjct: 10 IAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDVWFLD 69 Query: 114 YEYMAAYIENAKQVGRLENAIGWYHSHP 141 + Y+ E K++ E IGWYHS P Sbjct: 70 HNYIENMNEMCKKINAKEKLIGWYHSGP 97 >5CW3-A nrPDB Length = 255 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 2/104 (1%) Query: 68 HARSGGNLEVMGLMLGKVDGETMIIMDSFALP-VEGTETRVNAQAAAYEYMAAYIENAK- 125 HA S N EVMGL++G I L ++ + RV + AA E Sbjct: 24 HALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRVEISSEQLLKAAAEAERLTV 83 Query: 126 QVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVV 169 ++ R +GWYHSHP S +DV TQ Q FV ++ Sbjct: 84 ELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFVGLI 127 >5VFQ-Z nrPDB Length = 286 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 8/119 (6%) Query: 57 ISALALLKMVMH----ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAA 112 + L LL +V H + G V+G++LG + + + +SFA+P + + + Sbjct: 7 VHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFL 66 Query: 113 AYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVID 171 ++Y+ K+V E +GWYH+ P L D++ L +++ V V+ID Sbjct: 67 DHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVLVIID 121 >6MSD-Z nrPDB Length = 324 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 8/119 (6%) Query: 57 ISALALLKMVMH----ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAA 112 + L LL +V H + G V+G++LG + + + +SFA+P + + + Sbjct: 11 VHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFL 70 Query: 113 AYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVID 171 ++Y+ K+V E +GWYH+ P L D++ L +++ V V+ID Sbjct: 71 DHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVLVIID 125 >4R14-A nrPDB Length = 181 Score = 35.4 bits (80), Expect = 0.035, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 67 MHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQ 126 M ++ G ++V+G ++GK +G + +M+SF L E ++ EY E KQ Sbjct: 21 MRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDK---EYYYTKEEQFKQ 77 Query: 127 VGRLENAIGWY 137 V + +GWY Sbjct: 78 VFKELEFLGWY 88 >4D18-F nrPDB Length = 331 Score = 34.3 bits (77), Expect = 0.082, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 67 MHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQ 126 M ++ G ++V+G ++GK +G + +M+SF L E ++ EY E KQ Sbjct: 62 MRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDK---EYYYTKEEQFKQ 118 Query: 127 VGRLENAIGWY 137 V + +GWY Sbjct: 119 VFKELEFLGWY 129 >5A5T-F nrPDB Length = 364 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 70 RSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGR 129 R+ G V+G +LG VD ++ + + F++P +E V A E+ E K+V Sbjct: 116 RNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEV---AVDMEFAKNMYELHKKVSP 172 Query: 130 LENAIGWY 137 E +GWY Sbjct: 173 NELILGWY 180 >3J8B-F nrPDB Length = 327 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 70 RSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGR 129 R+ G V+G +LG VD ++ + + F++P +E V A E+ E K+V Sbjct: 109 RNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEV---AVDMEFAKNMYELHKKVSP 165 Query: 130 LENAIGWY 137 E +GWY Sbjct: 166 NELILGWY 173 >5CYV-A nrPDB Length = 146 Score = 31.2 bits (69), Expect = 0.68, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 14/74 (18%) Query: 265 QVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKAT------RDSCKTTIEAIHGL 318 Q+ L ++LE+ RG + L+ DR+ +KL AT RD K ++A HG Sbjct: 68 QIVGLVDELEE------RGLVVRTLDPSDRR--NKLIAATEEGRRLRDDAKARVDAAHGR 119 Query: 319 MSQVIKDKLFNQIN 332 + I D + NQ+ Sbjct: 120 YFEGIPDTVVNQMR 133 >5D9W-A nrPDB Length = 230 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%) Query: 142 GYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPD 197 G G W+ DV TQ++ +++ P ++ P S G F T+ K P D Sbjct: 83 GDGKWIPDSDVITQVIEEKYPTP---SLVTPPEYASVGSKIFSCFTTFLKSKDPND 135 >1KKH-A nrPDB Length = 317 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 7/64 (10%) Query: 10 QKTWELANNMQEAQSIDEIYKYDKKQQQEILA-------AKPWTKDHHYFKYCKISALAL 62 +KT EL N + + ++ DEI+K K E L K TK+H K IS L Sbjct: 203 KKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDFGKLMTKNHELLKKLNISTPKL 262 Query: 63 LKMV 66 ++V Sbjct: 263 DRIV 266 >5W6G-A nrPDB Length = 334 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 7/55 (12%) Query: 47 KDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVE 101 +D H K C + +A L++ GN V G +LG + E +I +S++ VE Sbjct: 42 EDSHNGKLCLLKGIAPLQL-------GNCSVAGWILGNPECELLISRESWSYIVE 89 >4IIC-A nrPDB Length = 841 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 295 KSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQINV 333 K+ D L KA ++C TI IH + V+ D+ ++ NV Sbjct: 509 KNGDNLIKAAANNCNNTIVVIHSV-GPVLVDEWYDHPNV 546 >1IHM-A nrPDB Length = 530 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Query: 182 NLGAFRTYPKGYKP--PDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKL 237 NLG F+ YP G+ P+ S Q +P+N + F ++Y L+ SS +L Sbjct: 469 NLGEFKAYPDGFLTCVPNGASSGPQQLPINGVFVFVSWVSRFYQLKPVGTASSARGRL 526 >3TEB-A nrPDB Length = 266 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 7/81 (8%) Query: 136 WYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKP 195 W +SH G+G + G+ V T+ + ++ F RTISA ++ + Y+ Sbjct: 81 WSNSHIGFGKYNEGVAVITRH-KIKAEDEFYCTFAQSVRTISARRI-----VSITINYEG 134 Query: 196 PD-EGPSEYQTIPLNKIEDFG 215 D E S + +P + ED G Sbjct: 135 QDIEFYSCHMNLPNCETEDMG 155 >4KIT-C nrPDB Length = 278 Score = 28.1 bits (61), Expect = 5.7, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 5/65 (7%) Query: 133 AIGWYHSHPGYGCWLSGIDVSTQ---MLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTY 189 +GW H+ P LS DV+T M + + ++I T + + G L A++ Sbjct: 117 PLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIII--TCSFTPGSCTLTAYKLT 174 Query: 190 PKGYK 194 P GY+ Sbjct: 175 PSGYE 179 >3VRD-B nrPDB Length = 401 Score = 28.1 bits (61), Expect = 6.3, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 131 ENA-IGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTY 189 ENA I W HPG + D + F E F A VI+ AGK+ A T Sbjct: 213 ENALIEW---HPGPDAAVVKTDTEAMTVETSFGETFKAAVINLIPPQRAGKIAQSASLTN 269 Query: 190 PKGYKPPD 197 G+ P D Sbjct: 270 DSGWCPVD 277 >1Z69-A nrPDB Length = 327 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 17/111 (15%) Query: 223 ALEVSYFKSSLDRKLLELLW------NKYWVNTLSSSSLLTNA---------DYTTGQVF 267 AL+++Y+ +++ + +W N+ +TL+ +L TN+ YT Sbjct: 13 ALKIAYYAKLSEQQGFDHVWITDHYNNRDVYSTLTVLALNTNSIKIGPGVTNSYTRNPAI 72 Query: 268 DLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGL 318 S S A++ G +LGL D+ + D + A + TT EAI + Sbjct: 73 TASSI--ASIAEISGGRAVLGLGPGDKATFDAMGIAWKKPLATTKEAIQAI 121 >5LOL-A nrPDB Length = 215 Score = 27.3 bits (59), Expect = 9.5, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 3/48 (6%) Query: 144 GCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPK 191 G W++ DV +L +++ EP + P S G GAF T+ K Sbjct: 69 GKWVADSDVIVGLLEEKYPEPSLKT---PPEFASVGSKIFGAFVTFLK 113 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4D10-E nrPDB 578 e-165 4F7O-A nrPDB 429 e-120 5L4K-V nrPDB 253 1e-67 4O8Y-B nrPDB 237 5e-63 5MPD-V nrPDB 234 3e-62 6FJU-A nrPDB 162 2e-40 5CW6-A nrPDB 143 1e-34 6MSD-Z nrPDB 142 2e-34 5VFQ-Z nrPDB 141 3e-34 5CW3-A nrPDB 132 2e-31 6FVW-U nrPDB 122 2e-28 3JCO-U nrPDB 120 6e-28 Sequences not found previously or not previously below threshold: 3J8B-H nrPDB 70 1e-12 6FEC-5 nrPDB 69 2e-12 5A5T-F nrPDB 65 5e-11 3J8B-F nrPDB 65 5e-11 4D18-F nrPDB 50 1e-06 4R14-A nrPDB 49 3e-06 4KIT-C nrPDB 37 0.012 2P87-A nrPDB 35 0.053 3EC7-A nrPDB 33 0.20 3ZX1-A nrPDB 32 0.56 5CYV-A nrPDB 31 0.60 4MWD-A nrPDB 30 1.5 3TEB-A nrPDB 28 5.2 3VRD-B nrPDB 28 6.2 2NPU-A nrPDB 28 7.5 1KKH-A nrPDB 27 8.2 >4D10-E nrPDB Length = 334 Score = 578 bits (1490), Expect = e-165, Method: Composition-based stats. Identities = 332/334 (99%), Positives = 334/334 (100%) Query: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL Sbjct: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 Query: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY Sbjct: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 Query: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK Sbjct: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 Query: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL Sbjct: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 Query: 241 LWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKL 300 LWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKL Sbjct: 241 LWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKL 300 Query: 301 AKATRDSCKTTIEAIHGLMSQVIKDKLFNQINVA 334 AKATRDSCKTTIEAIHGLMSQVIKDKLFNQIN++ Sbjct: 301 AKATRDSCKTTIEAIHGLMSQVIKDKLFNQINIS 334 >4F7O-A nrPDB Length = 257 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 257/257 (100%), Positives = 257/257 (100%) Query: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL Sbjct: 1 MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISAL 60 Query: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY Sbjct: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 Query: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK Sbjct: 121 IENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGK 180 Query: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL Sbjct: 181 VNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLEL 240 Query: 241 LWNKYWVNTLSSSSLLT 257 LWNKYWVNTLSSSSLLT Sbjct: 241 LWNKYWVNTLSSSSLLT 257 >5L4K-V nrPDB Length = 310 Score = 253 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 80/206 (38%), Positives = 119/206 (57%), Gaps = 11/206 (5%) Query: 53 KYCKISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQA 111 + IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A Sbjct: 29 EQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVD 88 Query: 112 AAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVID 171 ++ A ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+D Sbjct: 89 PVFQ--AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVD 146 Query: 172 PTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALE 225 P +++ GKV + AFR P + T L + + + YY++ Sbjct: 147 PIQSVK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSIT 204 Query: 226 VSYFKSSLDRKLLELLWNKYWVNTLS 251 ++Y K+ L++K+L L K W+ L+ Sbjct: 205 INYRKNELEQKMLLNLHKKSWMEGLT 230 >4O8Y-B nrPDB Length = 240 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 84/211 (39%), Positives = 122/211 (57%), Gaps = 14/211 (6%) Query: 46 TKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTE 104 TK+ Y IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT Sbjct: 24 TKETVY-----ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTG 78 Query: 105 TRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEP 164 V A ++ A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q Sbjct: 79 VSVEAVDDVFQ--AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSR 136 Query: 165 FVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNKIE-DFGVHC--K 219 VAVV+DP +++ GKV + AFR G + P + T LNK +H + Sbjct: 137 AVAVVVDPIQSVK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNR 195 Query: 220 QYYALEVSYFKSSLDRKLLELLWNKYWVNTL 250 YY+L + Y K++ + K+L L + W + L Sbjct: 196 HYYSLNIDYHKTAKETKMLMNLHKEQWQSGL 226 >5MPD-V nrPDB Length = 306 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 84/211 (39%), Positives = 122/211 (57%), Gaps = 14/211 (6%) Query: 46 TKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTE 104 TK+ Y IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT Sbjct: 23 TKETVY-----ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTG 77 Query: 105 TRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEP 164 V A ++ A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q Sbjct: 78 VSVEAVDDVFQ--AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSR 135 Query: 165 FVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNKIE-DFGVHC--K 219 VAVV+DP +++ GKV + AFR G + P + T LNK +H + Sbjct: 136 AVAVVVDPIQSVK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNR 194 Query: 220 QYYALEVSYFKSSLDRKLLELLWNKYWVNTL 250 YY+L + Y K++ + K+L L + W + L Sbjct: 195 HYYSLNIDYHKTAKETKMLMNLHKEQWQSGL 225 >6FJU-A nrPDB Length = 228 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 51/146 (34%), Positives = 70/146 (47%), Gaps = 11/146 (7%) Query: 46 TKDHHYFK---YCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEG 102 T ++ YF+ +I LAL K+V HA S EV GL++GK G+ + I D+ G Sbjct: 17 TTENLYFQGHMRVRIYPLALAKVVKHAASSLQREVAGLLVGKSAGKVLEIWDAVTGEQYG 76 Query: 103 TETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQ 162 T V MA E + + +GWYHSHPG +LS D+ TQ Q Sbjct: 77 TPAYVQLDEMV---MAKVAEELSKSDKNLYIVGWYHSHPGLDVFLSPTDIDTQKRYQAMF 133 Query: 163 EPFVAVVIDP-----TRTISAGKVNL 183 VA+V+DP TR IS+ K + Sbjct: 134 SKAVALVVDPVDYAKTRRISSLKFKV 159 >5CW6-A nrPDB Length = 262 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 6/137 (4%) Query: 61 ALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAY 120 A L + HA S EVMGL +G+VD ++ + S + + + + + + AA Sbjct: 14 AFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPEQLSAAS 73 Query: 121 IEN---AKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVID---PTR 174 E A+ GR +GWYHSHP W S +DV TQ + Q + FV ++ + Sbjct: 74 TEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDK 133 Query: 175 TISAGKVNLGAFRTYPK 191 G+V F++ Sbjct: 134 NTKTGRVLYTCFQSVQA 150 >6MSD-Z nrPDB Length = 324 Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Query: 53 KYCKISALALLKMVMH----ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVN 108 + + L LL +V H + G V+G++LG + + + +SFA+P + + + Sbjct: 7 QKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDS 66 Query: 109 AQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAV 168 ++Y+ K+V E +GWYH+ P L D++ L +++ V V Sbjct: 67 VWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVLV 122 Query: 169 VID 171 +ID Sbjct: 123 IID 125 >5VFQ-Z nrPDB Length = 286 Score = 141 bits (356), Expect = 3e-34, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Query: 53 KYCKISALALLKMVMH----ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVN 108 + + L LL +V H + G V+G++LG + + + +SFA+P + + + Sbjct: 3 QKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDS 62 Query: 109 AQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAV 168 ++Y+ K+V E +GWYH+ P L D++ L +++ V V Sbjct: 63 VWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVLV 118 Query: 169 VID 171 +ID Sbjct: 119 IID 121 >5CW3-A nrPDB Length = 255 Score = 132 bits (332), Expect = 2e-31, Method: Composition-based stats. Identities = 34/124 (27%), Positives = 50/124 (40%), Gaps = 2/124 (1%) Query: 48 DHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPV-EGTETR 106 D + ++ + + HA S N EVMGL++G I L + + R Sbjct: 4 DDSSLQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDR 63 Query: 107 VNAQAAAYEYMAAYIENAK-QVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPF 165 V + AA E ++ R +GWYHSHP S +DV TQ Q F Sbjct: 64 VEISSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSF 123 Query: 166 VAVV 169 V ++ Sbjct: 124 VGLI 127 >6FVW-U nrPDB Length = 304 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%) Query: 53 KYCKISALALLKMVMH---ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNA 109 + I+ L LL + H ++ N +G++LG + T+ + +SFALP E E + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDV 65 Query: 110 QAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPF-VAV 168 + Y+ E K++ E IGWYHS P L D+ L +++ + + + Sbjct: 66 WFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQNNPLLL 121 Query: 169 VID 171 ++D Sbjct: 122 IVD 124 >3JCO-U nrPDB Length = 338 Score = 120 bits (302), Expect = 6e-28, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%) Query: 53 KYCKISALALLKMVMH---ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNA 109 + I+ L LL + H ++ N +G++LG + T+ + +SFALP E E + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDV 65 Query: 110 QAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPF-VAV 168 + Y+ E K++ E IGWYHS P L D+ L +++ + + + Sbjct: 66 WFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQNNPLLL 121 Query: 169 VID 171 ++D Sbjct: 122 IVD 124 >3J8B-H nrPDB Length = 343 Score = 70.1 bits (170), Expect = 1e-12, Method: Composition-based stats. Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 7/148 (4%) Query: 53 KYCKISALALLKMVMHARSGGN--LEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQ 110 K +I L +LK++ H + G V G++LG V + + I + F P T +A Sbjct: 37 KQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQH---TEDDAD 93 Query: 111 AAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVI 170 +Y + + + V +GWY S YG +++ + +Q Q E V ++ Sbjct: 94 FDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVVLIY 152 Query: 171 DPTRTISAGKVNLGAFRTYPKGYKPPDE 198 DP +T + G ++L A+R PK + E Sbjct: 153 DPIKT-AQGSLSLKAYRLTPKLMEVCKE 179 >6FEC-5 nrPDB Length = 352 Score = 69.3 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 7/145 (4%) Query: 53 KYCKISALALLKMVMHARSGGN--LEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQ 110 K +I L +LK++ H + G V G++LG V + + I + F P T +A Sbjct: 37 KQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQH---TEDDAD 93 Query: 111 AAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVI 170 +Y + + + V +GWY S YG +++ + +Q Q E V ++ Sbjct: 94 FDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVVLIY 152 Query: 171 DPTRTISAGKVNLGAFRTYPKGYKP 195 DP +T + G ++L A+R PK + Sbjct: 153 DPIKT-AQGSLSLKAYRLTPKLMEV 176 >5A5T-F nrPDB Length = 364 Score = 64.7 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 56/145 (38%), Gaps = 13/145 (8%) Query: 55 CKISALALLKMVM--HARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAA 112 ++ + L +V R+ G V+G +LG VD ++ + + F++P +E V Sbjct: 99 VRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAV--- 155 Query: 113 AYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDP 172 E+ E K+V E +GWY + V + + + +D Sbjct: 156 DMEFAKNMYELHKKVSPNELILGWYATGHDIT----EHSVLIHEYYSREAPNPIHLTVD- 210 Query: 173 TRTISAGKVNLGAFRTYPKGYKPPD 197 ++ G++++ A+ P Sbjct: 211 -TSLQNGRMSIKAY--VSTSMGVPG 232 >3J8B-F nrPDB Length = 327 Score = 64.7 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 55/134 (41%), Gaps = 11/134 (8%) Query: 55 CKISALALLKMVM--HARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAA 112 ++ + L +V R+ G V+G +LG VD ++ + + F++P +E V Sbjct: 92 VRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAV--- 148 Query: 113 AYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDP 172 E+ E K+V E +GWY + V + + + +D Sbjct: 149 DMEFAKNMYELHKKVSPNELILGWYATGHDIT----EHSVLIHEYYSREAPNPIHLTVD- 203 Query: 173 TRTISAGKVNLGAF 186 ++ G++++ A+ Sbjct: 204 -TSLQNGRMSIKAY 216 >4D18-F nrPDB Length = 331 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 56/134 (41%), Gaps = 12/134 (8%) Query: 55 CKISALALLKMVMH-----ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNA 109 + L +L + H ++ G ++V+G ++GK +G + +M+SF L E ++ Sbjct: 45 VALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKI-- 102 Query: 110 QAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVV 169 EY E KQV + +GWY + G D+ + E + + Sbjct: 103 -IIDKEYYYTKEEQFKQVFKELEFLGWYTT----GGPPDPSDIHVHKQVCEIIESPLFLK 157 Query: 170 IDPTRTISAGKVNL 183 ++P + V++ Sbjct: 158 LNPMTKHTDLPVSV 171 >4R14-A nrPDB Length = 181 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 56/134 (41%), Gaps = 12/134 (8%) Query: 55 CKISALALLKMVMH-----ARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNA 109 + L +L + H ++ G ++V+G ++GK +G + +M+SF L E ++ Sbjct: 4 VALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKI-- 61 Query: 110 QAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVV 169 EY E KQV + +GWY + G D+ + E + + Sbjct: 62 -IIDKEYYYTKEEQFKQVFKELEFLGWYTT----GGPPDPSDIHVHKQVCEIIESPLFLK 116 Query: 170 IDPTRTISAGKVNL 183 ++P + V++ Sbjct: 117 LNPMTKHTDLPVSV 130 >4KIT-C nrPDB Length = 278 Score = 37.0 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 48/131 (36%), Gaps = 21/131 (16%) Query: 71 SGGNLEVMGLMLGKV---DGETMIIMDSFALPVEGTETRVNA--QAAAYEYMAAYIENAK 125 S ++ G + G + + I +P GT V+ Q +EY+ Sbjct: 61 SDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYL-------- 112 Query: 126 QVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVA---VVIDPTRTISAGKVN 182 + +GW H+ P LS DV+T + ++I T + + G Sbjct: 113 ---KEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIII--TCSFTPGSCT 167 Query: 183 LGAFRTYPKGY 193 L A++ P GY Sbjct: 168 LTAYKLTPSGY 178 >2P87-A nrPDB Length = 273 Score = 34.7 bits (78), Expect = 0.053, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 25/135 (18%) Query: 69 ARSGGNLEVMGLMLGKV---DGETMIIMDSFALPVEGTETRVNA--QAAAYEYMAAYIEN 123 S ++ G M G + + I +P G+ +VN Q +E + Sbjct: 53 TISDLRTQIAGFMYGVSPPDNPQVKEIRCIVLVPQTGSHQQVNLPTQLPDHELL------ 106 Query: 124 AKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQ-----EPFVAVVIDPTRTISA 178 R +GW H+ P LS DV+T E V + T + + Sbjct: 107 -----RDFEPLGWMHTQPNELPQLSPQDVTTHAKLLTDNISWDGEKTVMI----TCSFTP 157 Query: 179 GKVNLGAFRTYPKGY 193 G V+L A++ P GY Sbjct: 158 GSVSLTAYKLTPSGY 172 >3EC7-A nrPDB Length = 357 Score = 32.7 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 28/133 (21%) Query: 148 SGIDVSTQMLNQQ---FQEPFVAVVIDPTRTI-----SAGK--VNLGAFRTYPKGYKPPD 197 + DV+ LN F E +AV + + GK V +G R Y KGY Sbjct: 99 AHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLK 158 Query: 198 EGPSEYQTIPLNKI-EDFGVHCKQYYALEVSYFKS--SLDRKLLELLWNKYWVNTLSSSS 254 I +I + VH + Y A V +K+ ++ L+ + +W Sbjct: 159 ------NIIDSGEIGQPLMVHGRHYNASTVPEYKTPQAIYETLIHEIDVMHW-------- 204 Query: 255 LLTNADYTTGQVF 267 L N DY T +V+ Sbjct: 205 -LLNEDYKTVKVY 216 >3ZX1-A nrPDB Length = 481 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 72 GGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLE 131 G LE+ L+ K+ T I +P + + ++ + A E + + Sbjct: 89 GDKLEI--LVKNKLKEATTIHWHGVPVPPDQDG-------SPHDPILAGEERIYRFEIPQ 139 Query: 132 NAIG--WYHSHPGYG 144 ++ G WYH HP Y Sbjct: 140 DSAGTYWYHPHPHYT 154 >5CYV-A nrPDB Length = 146 Score = 31.2 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 14/73 (19%) Query: 265 QVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKAT------RDSCKTTIEAIHGL 318 Q+ L ++LE+ RG + L+ DR+ +KL AT RD K ++A HG Sbjct: 68 QIVGLVDELEE------RGLVVRTLDPSDRR--NKLIAATEEGRRLRDDAKARVDAAHGR 119 Query: 319 MSQVIKDKLFNQI 331 + I D + NQ+ Sbjct: 120 YFEGIPDTVVNQM 132 >4MWD-A nrPDB Length = 542 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 31/72 (43%), Gaps = 9/72 (12%) Query: 80 LMLGKVDGETMIIMDSFALPV--------EGTETRVNAQA-AAYEYMAAYIENAKQVGRL 130 + LG+ +G I +SF P +G +V+ ++ +++ + Sbjct: 123 IYLGRYEGWYSISDESFLTPQNITDGVDKDGNPCKVSLESGHVVTWVSEENYMFRLSAFR 182 Query: 131 ENAIGWYHSHPG 142 E + WYH++PG Sbjct: 183 ERLLEWYHANPG 194 >3TEB-A nrPDB Length = 266 Score = 28.1 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 49/125 (39%), Gaps = 2/125 (1%) Query: 59 ALALLKMVMHA-RSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYM 117 A+ +L + +HA +E + ++ + + ++ + + Y Sbjct: 3 AMKILTVNVHAWLEENQMEKIDILARTIAEKQYDVIAMQEVNQLMNNKIIFDDIREENYA 62 Query: 118 AAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTIS 177 +E ++ + + W +SH G+G + G+ V T+ + E F RTIS Sbjct: 63 WVLLETLQKYTDTDYYLHWSNSHIGFGKYNEGVAVITRHKIKAEDE-FYCTFAQSVRTIS 121 Query: 178 AGKVN 182 A ++ Sbjct: 122 ARRIV 126 >3VRD-B nrPDB Length = 401 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 29/86 (33%), Gaps = 3/86 (3%) Query: 122 ENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKV 181 E G I W HPG + D + F E F A VI+ AGK+ Sbjct: 205 ERLYGFGTENALIEW---HPGPDAAVVKTDTEAMTVETSFGETFKAAVINLIPPQRAGKI 261 Query: 182 NLGAFRTYPKGYKPPDEGPSEYQTIP 207 A T G+ P D E P Sbjct: 262 AQSASLTNDSGWCPVDIRTFESSLQP 287 >2NPU-A nrPDB Length = 126 Score = 27.7 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 228 YFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRG 283 YF+ +++ + +LW++ W L +S L + +F E LE A + RG Sbjct: 21 YFQGAMELIRVPILWHEMWHEGLEEASRLYFGERNVKGMF---EVLEPLHAMMERG 73 >1KKH-A nrPDB Length = 317 Score = 27.4 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 7/65 (10%) Query: 10 QKTWELANNMQEAQSIDEIYKYDKKQQQEILA-------AKPWTKDHHYFKYCKISALAL 62 +KT EL N + + ++ DEI+K K E L K TK+H K IS L Sbjct: 203 KKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDFGKLMTKNHELLKKLNISTPKL 262 Query: 63 LKMVM 67 ++V Sbjct: 263 DRIVD 267 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.132 0.361 Lambda K H 0.267 0.0403 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,435,993 Number of Sequences: 36641 Number of extensions: 466292 Number of successful extensions: 1399 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1327 Number of HSP's gapped (non-prelim): 63 length of query: 334 length of database: 10,336,785 effective HSP length: 98 effective length of query: 236 effective length of database: 6,745,967 effective search space: 1592048212 effective search space used: 1592048212 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.4 bits)