BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O35744 (398 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1E9L-A nrPDB 787 0.0 3RM8-A nrPDB 552 e-157 4WKA-A nrPDB 380 e-106 1WB0-A nrPDB 377 e-105 5WUS-A nrPDB 331 4e-91 4P8U-A nrPDB 326 1e-89 5WV8-A nrPDB 325 2e-89 1HJW-A nrPDB 321 3e-88 5XEP-A nrPDB 310 7e-85 2QF8-A nrPDB 309 1e-84 6G9C-A nrPDB 281 3e-76 5Y29-A nrPDB 256 1e-68 3WKZ-A nrPDB 250 7e-67 3W4R-A nrPDB 247 8e-66 5Y2C-A nrPDB 245 3e-65 4MNK-A nrPDB 161 4e-40 3AQU-A nrPDB 157 6e-39 5GZU-A nrPDB 156 2e-38 6BT9-A nrPDB 151 6e-37 1ITX-A nrPDB 148 5e-36 3ALF-A nrPDB 140 1e-33 4URI-A nrPDB 137 1e-32 3WD0-A nrPDB 115 3e-26 6EPB-A nrPDB 115 4e-26 6F8N-A nrPDB 115 4e-26 5ZL9-A nrPDB 114 1e-25 1JNE-A nrPDB 111 7e-25 3G6L-A nrPDB 108 4e-24 3CHF-A nrPDB 108 4e-24 5GQB-A nrPDB 107 6e-24 5Z7M-A nrPDB 107 9e-24 3QOK-A nrPDB 106 1e-23 1LL6-A nrPDB 102 2e-22 5XWF-A nrPDB 102 4e-22 1KFW-A nrPDB 98 6e-21 3ARQ-A nrPDB 97 1e-20 4DWS-C nrPDB 88 7e-18 6OGD-C nrPDB 87 1e-17 5DF0-A nrPDB 85 5e-17 4A5Q-A nrPDB 80 1e-15 4W5U-B nrPDB 75 7e-14 4TXG-A nrPDB 64 9e-11 4Q6T-A nrPDB 49 3e-06 3CO4-A nrPDB 49 4e-06 4WIW-A nrPDB 49 5e-06 5JH8-A nrPDB 42 3e-04 3CZ8-A nrPDB 36 0.032 3VPX-A nrPDB 36 0.034 1LEH-A nrPDB 32 0.54 2Y8V-A nrPDB 32 0.67 3K4O-A nrPDB 31 0.95 4RL3-A nrPDB 31 1.0 4TX8-A nrPDB 30 1.5 3EBV-A nrPDB 30 2.0 4LRU-A nrPDB 30 2.1 5AN9-C nrPDB 30 2.3 6MJ1-A nrPDB 30 2.6 6ACF-A nrPDB 30 2.7 1PYS-B nrPDB 29 4.5 3BF5-A nrPDB 28 4.8 3SIM-A nrPDB 28 5.5 3ZVX-A nrPDB 28 7.6 3GX8-A nrPDB 28 9.2 3N18-A nrPDB 28 9.5 >1E9L-A nrPDB Length = 377 Score = 787 bits (2033), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN Sbjct: 1 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY Sbjct: 61 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS Sbjct: 121 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 180 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI Sbjct: 181 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 240 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP Sbjct: 241 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 300 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS Sbjct: 301 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 360 Query: 382 TLKGDLNIHSASCKGPY 398 TLKGDLNIHSASCKGPY Sbjct: 361 TLKGDLNIHSASCKGPY 377 >3RM8-A nrPDB Length = 395 Score = 552 bits (1422), Expect = e-157, Method: Compositional matrix adjust. Identities = 256/376 (68%), Positives = 305/376 (81%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 YQL CY+T+WA+ RP G F P +I+PCLCTHLIYAFAGMQNNEIT D+ Y+A N Sbjct: 1 YQLTCYFTNWAQYRPGLGRFMPDDINPCLCTHLIYAFAGMQNNEITTIEWNDVTLYQAFN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 GLK+KN++LKTLLAIGGW FG APF+AMVSTP+NRQ FI SVI+FLRQY FDGL+ DW+Y Sbjct: 61 GLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEY 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PGSRGSPP+DKHLF+VLV+EMR+AFE+E+ + + PRL++T+ A I I+SGY+IP+LS Sbjct: 121 PGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLS 180 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 Q LDYI VMTYDLH +GYTGENSPLYK P D G +A LNVD +++YWKD+GA +EKLI Sbjct: 181 QYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLI 240 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 VGFP YGH FILS+PS TGIGAPT GP G Y ESG+ AYYE+CTFL GAT+ WDAP Sbjct: 241 VGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAP 300 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 QEVPYAYQGN WVGYDNV+SF +KAQWLK N GGA+VW +D+DDF+G+FC+Q FPL S Sbjct: 301 QEVPYAYQGNVWVGYDNVKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLIS 360 Query: 382 TLKGDLNIHSASCKGP 397 TLK L + SASC P Sbjct: 361 TLKKALGLQSASCTAP 376 >4WKA-A nrPDB Length = 377 Score = 380 bits (975), Expect = e-106, Method: Compositional matrix adjust. Identities = 176/367 (47%), Positives = 250/367 (68%), Gaps = 2/367 (0%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 +L+CY+T+WA+ R E F P ++DP LCTHLIYAFAGM N++++ T D Y+ NG Sbjct: 2 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 61 Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 142 LK N +LKTLLAIGGW FG F+ MV+T NRQ F+ S IRFLR+Y+FDGL+LDW+YP Sbjct: 62 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 121 Query: 143 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 GS+GSP DK F+ LV+++ AF++E+ RLLL++ + +GY++ +++Q Sbjct: 122 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 181 Query: 203 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 262 +LD++ +M YD H + TG NSPLYK + G +A LNVD+ + W G + KLI+ Sbjct: 182 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 241 Query: 263 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQ 322 G P YG +F L+ S T +GAP +G PG +T E G+LAYYEVC++ +GAT+ Q Sbjct: 242 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQ 299 Query: 323 EVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTST 382 +VPY ++ N+WVG+D+V SFK K +LK LGGA+VW LD+DDF+G C+Q +PL T Sbjct: 300 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQT 359 Query: 383 LKGDLNI 389 L+ +L++ Sbjct: 360 LRQELSL 366 >1WB0-A nrPDB Length = 445 Score = 377 bits (967), Expect = e-105, Method: Compositional matrix adjust. Identities = 176/367 (47%), Positives = 250/367 (68%), Gaps = 2/367 (0%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 +L+CY+T+WA+ R E F P ++DP LCTHLIYAFAGM N++++ T D Y+ NG Sbjct: 2 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 61 Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 142 LK N +LKTLLAIGGW FG F+ MV+T NRQ F+ S IRFLR+Y+FDGL+LDW+YP Sbjct: 62 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 121 Query: 143 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 GS+GSP DK F+ LV+++ AF++E+ RLLL++ + +GY++ +++Q Sbjct: 122 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 181 Query: 203 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 262 +LD++ +M YD H + TG NSPLYK + G +A LNVD+ + W G + KLI+ Sbjct: 182 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 241 Query: 263 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQ 322 G P YG +F L+ S T +GAP +G PG +T E G+LAYYEVC++ +GAT+ Q Sbjct: 242 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQ 299 Query: 323 EVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTST 382 +VPY ++ N+WVG+D+V SFK K +LK LGGA+VW LD+DDF+G C+Q +PL T Sbjct: 300 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQT 359 Query: 383 LKGDLNI 389 L+ +L++ Sbjct: 360 LRQELSL 366 >5WUS-A nrPDB Length = 460 Score = 331 bits (848), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 165/379 (43%), Positives = 230/379 (60%), Gaps = 8/379 (2%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 Q++CY TSW+ RP G F P N+DP LCTH+IYAFA ++++++T E+D Y+ + Sbjct: 3 QVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVA 62 Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 142 L++KN LK LLAIGGW FG PF + S F+ I FLR Y F+GL++DW+YP Sbjct: 63 LREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYP 122 Query: 143 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 RG+ D+ F L+KE+R AFE E+ PRLLLT+ + I +GY +PE+S+ Sbjct: 123 --RGA--DDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISK 178 Query: 203 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 262 LD+I VMTYD H + G NSPL+ L VD W GA EKL++ Sbjct: 179 YLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMI 238 Query: 263 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNE-GATEVWDAP 321 G P YG +F L + ++ IGAP G G++T+E+G ++YYE+C FL E T VWD Sbjct: 239 GMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNE 298 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 Q VP+AY+ ++WVG+D+ RS K K WLK+ GG +VW +DMDDF GS C +PL + Sbjct: 299 QMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGS-CGTGKYPLIT 357 Query: 382 TLKGDLNIHSASCK--GPY 398 +K +L+ + + GPY Sbjct: 358 AMKQELSGYKVKLEYDGPY 376 >4P8U-A nrPDB Length = 371 Score = 326 bits (835), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 162/369 (43%), Positives = 239/369 (64%), Gaps = 9/369 (2%) Query: 21 SYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEAL 80 SY+L+CY+T+W++DR G F P NIDP LC+HLIY+FA ++NN++ + ++ Y+ + Sbjct: 7 SYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTI 66 Query: 81 NGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQ 140 N LK KN +LK LL+IGG+ FG F MV + +R FI S+I FLR +NFDGL++ W Sbjct: 67 NSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWI 126 Query: 141 YPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPEL 200 YP K+ F+VL+ E+ +AF+++ + RLLLT + +I + Y++ +L Sbjct: 127 YPDQ-----KENTHFTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVEKL 181 Query: 201 SQSLDYIQVMTYDLHDP--KDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASE 258 ++ LD+I ++++D H K TG NSPL K D G S+ NV+ + YW G SE Sbjct: 182 AKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSE 241 Query: 259 KLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVW 318 K+++G P YGH+F L+ ++T +GAP G G T+ SG LAYYE+C FL +GA W Sbjct: 242 KVVMGIPTYGHSFTLAS-AETTVGAPASGPGAAGPITESSGFLAYYEICQFL-KGAKITW 299 Query: 319 DAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFP 378 Q+VPYA +GN+WVGYD+V+S + K Q+LK+ NLGGA++W +DMDDF+G C+Q +P Sbjct: 300 LQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYP 359 Query: 379 LTSTLKGDL 387 L +K L Sbjct: 360 LVQAVKRSL 368 >5WV8-A nrPDB Length = 482 Score = 325 bits (833), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 166/374 (44%), Positives = 228/374 (60%), Gaps = 11/374 (2%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEIT-YTHEQDLRD---- 76 Y+++CYYT+W++ R G F P +I P LCTH+I+AF ++ +++ + + +D Sbjct: 93 YKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTG 152 Query: 77 -YEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGL 135 Y+ +N LK N +LKTLLAIGGW FG F M +T RQ FI S I +LR NFDGL Sbjct: 153 LYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGL 212 Query: 136 NLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGY 195 ++DW YP +G DK + +L+KE+R+AFE E+ E PRLLLT+ D IKSGY Sbjct: 213 DIDWLYP--KGG--DDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGY 268 Query: 196 KIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGA 255 +P ++ LD+I +M YD H + TG N+PLY D L+VD W GA Sbjct: 269 DVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGA 328 Query: 256 ASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGAT 315 EKLI+G P YG TF LS+P+ + +P G G+YT ESG LAYYEVC L G Sbjct: 329 PKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGA 388 Query: 316 EVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFC-HQ 374 VWD +VPYA G++WVG+D+ +S + K +W+KDN+ GGA+VW +DMDDFSG C Sbjct: 389 YVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGN 448 Query: 375 RHFPLTSTLKGDLN 388 +PL ++ +L Sbjct: 449 VKYPLIGAMREELR 462 >1HJW-A nrPDB Length = 362 Score = 321 bits (823), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 171/367 (46%), Positives = 228/367 (62%), Gaps = 9/367 (2%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 Y+L+CYYTSW++ R +GS P +D LCTH+IY+FA + N+ I D+ Y LN Sbjct: 1 YKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 LK++N LKTLL++GGW FG FS + S Q+R+ FI+SV FLR + FDGL+L W Y Sbjct: 61 TLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLY 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PG R DK F+ L+KEM+ F +E+ LL + AG + I S Y I ++S Sbjct: 121 PGRR-----DKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKV-TIDSSYDIAKIS 174 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 Q LD+I +MTYD H G TG +SPL++ D N D + Y GA + KL+ Sbjct: 175 QHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLV 234 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 +G P +G +F L+ S+TG+GAP G PG++T E+G LAYYE+C FL GAT Sbjct: 235 MGIPTFGRSFTLAS-SETGVGAPISGPGIPGRFTKEAGTLAYYEICDFL-RGATVHRILG 292 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQR-HFPLT 380 Q+VPYA +GN+WVGYD+ S K K Q+LKD L GA+VW LD+DDF GSFC Q FPLT Sbjct: 293 QQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLT 352 Query: 381 STLKGDL 387 + +K L Sbjct: 353 NAIKDAL 359 >5XEP-A nrPDB Length = 381 Score = 310 bits (794), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 165/388 (42%), Positives = 240/388 (61%), Gaps = 9/388 (2%) Query: 1 MAKLILVTGLAILLNVQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAG 60 M +TG A+L+ +Q S+Y+L+CY+TSW++ R GSF P I P LCTH+IY+FA Sbjct: 1 MGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFAN 60 Query: 61 MQNNEITYTHE-QDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIF 119 + ++ + T E D +Y+ LN LK +NT LKTLL++GGWKFG FS + S + R F Sbjct: 61 ISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGGKRFSEIASNTERRTAF 120 Query: 120 IQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLL 179 ++SV FLR Y FDGL+L W YP R DK FS L+KE+ F +E V+ +LL Sbjct: 121 VRSVAPFLRSYGFDGLDLAWLYPRLR-----DKQYFSTLIKELNAEFTKE-VQPGREKLL 174 Query: 180 LTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSA 239 L++ + I +GY I +++Q LD+I +MTYD H TG +SPL++ D Sbjct: 175 LSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDR 234 Query: 240 DLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESG 299 NV+ + Y GA + KL++G P +G +F L+ S+ +GAP G PG++T E+G Sbjct: 235 YSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLAS-SENQLGAPISGEGLPGRFTKEAG 293 Query: 300 LLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVV 359 LAYYE+C FL +GA + ++VP+A +GN+WVGY++ S K K ++LK+ L GA+V Sbjct: 294 TLAYYEICDFL-KGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVRFLKEKKLAGAMV 352 Query: 360 WPLDMDDFSGSFCHQRHFPLTSTLKGDL 387 W LD+DDF G+ + FPLT+ +K L Sbjct: 353 WALDLDDFQGTCQPKEFFPLTNAIKDAL 380 >2QF8-A nrPDB Length = 361 Score = 309 bits (792), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 167/364 (45%), Positives = 227/364 (62%), Gaps = 10/364 (2%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 Y+L+CYYTSW++ R +GS P IDP LCTH+IY+FA + NNEI D+ Y+ LN Sbjct: 1 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 LK++N LKTLL++GGW +G FS + S Q+R+ FI+SV FLR + FDGL+L W + Sbjct: 61 TLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLW 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PG R DK + LVKEM+ F E+ LL + AG I I GY I ++S Sbjct: 121 PGWR-----DKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVTAGKI-AIDRGYDIAQIS 174 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 + LD+I ++TYD H G +SPL++ D S N D +SY GA + KL+ Sbjct: 175 RHLDFISLLTYDFHGAWRQTVGHHSPLFRGNED-ASSRFSNADYAVSYMLRLGAPANKLV 233 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 +G P +G ++ L+ SKT +GAP G PG++T G+LAYYE+C FL+ GAT Sbjct: 234 MGIPTFGRSYTLAS-SKTDVGAPISGPGIPGRFTKWKGILAYYEICDFLH-GATTHRFRD 291 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQR-HFPLT 380 Q+VPYA +GN+WV YD+ S K KA++LK+ L GA+VW LD+DDF G+FC Q FPLT Sbjct: 292 QQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLT 351 Query: 381 STLK 384 S +K Sbjct: 352 SAIK 355 >6G9C-A nrPDB Length = 495 Score = 281 bits (719), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 144/364 (39%), Positives = 204/364 (56%), Gaps = 10/364 (2%) Query: 26 CYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRD--YEALNGL 83 CY+T+WA+ RP G + P + LC ++ YAFA + ++ E + D Y + Sbjct: 37 CYFTNWAQYRPGNGKYNPEHYQANLCEYIFYAFAKLNDDFTVDQFEWNDIDVLYPGVMKQ 96 Query: 84 KDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPG 143 K +LK LL++GGW G A F M +T NR FI S++ FL+Q FDG +LDW+YP Sbjct: 97 KSSQPDLKVLLSLGGWNAGTATFKKMAATYSNRAKFISSLVSFLQQNKFDGFDLDWEYPE 156 Query: 144 SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQS 203 S DK + +L +E+ FEE + RLL T+ + + +GY +P L++ Sbjct: 157 S-----SDKENYLLLCQEILAKFEEVAKCTSTSRLLFTAAVSANPKTVDAGYDVPALAKV 211 Query: 204 LDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVG 263 LD++ +M YD H + TG NSPLY D + NV+ YW D G +++I+G Sbjct: 212 LDFVNLMCYDFHGAWETQTGINSPLYSRKEDSSEFKMWNVEQSSKYWSDKGMPKKQIIIG 271 Query: 264 FPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQE 323 P YG + LSD SKT IGAP + +Y E+G+++YYEVC L+ GA VWD + Sbjct: 272 LPTYGRGWTLSDASKTDIGAPAQGSSTATEYLREAGVISYYEVCQKLSSGAKRVWDDESK 331 Query: 324 VPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQ---RHFPLT 380 PY QGN+W YD+V S K K W+K N GGA VW LD DDF GSFC + + +PL Sbjct: 332 TPYLVQGNQWFSYDDVESMKAKINWIKQENYGGAFVWTLDYDDFLGSFCTEHNGKKYPLI 391 Query: 381 STLK 384 S ++ Sbjct: 392 SLMQ 395 >5Y29-A nrPDB Length = 377 Score = 256 bits (653), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 148/383 (38%), Positives = 215/383 (56%), Gaps = 26/383 (6%) Query: 18 LGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQ----D 73 L S Y+L+CYYT+W+ RP G + P +IDP LCTH++Y FA + N+ + H+ D Sbjct: 3 LNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYD 62 Query: 74 LRDYEALNGLKDKNTELKTLLAIGGWKFGPA-PFSAMVSTPQNRQIFIQSVIRFLRQYNF 132 R YE + ++ K +K LA+GGW +S +V+ P R F+Q + FL +Y F Sbjct: 63 NRFYERV--VEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGF 120 Query: 133 DGLNLDWQYPG------SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAG 186 DGL+LDW+YP S+G P DK F+ LV E+ + + LLL++ + Sbjct: 121 DGLDLDWEYPKCWQVDCSKG-PDSDKQGFADLVHELSAVLKPKG-------LLLSAAVSP 172 Query: 187 IIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSI 246 VI +GY +P L++ LD+I VMTYD H D TG +PLY P D + N + Sbjct: 173 NKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDD--DTTYFNANYT 230 Query: 247 ISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEV 306 I YW + G + K+++G P YG +F + + G+ P G PG+YT G LAYYE+ Sbjct: 231 IHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEI 290 Query: 307 CTFL-NEGATEVWDAPQEV-PYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDM 364 C + N G T V D Q + PYAY+GN+WV +D+V K K ++K NLGG ++W LD+ Sbjct: 291 CDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDL 350 Query: 365 DDFSGSFCHQRHFPLTSTLKGDL 387 DD+ C Q PL + +K +L Sbjct: 351 DDYRNR-CGQGKHPLLNAIKTEL 372 >3WKZ-A nrPDB Length = 395 Score = 250 bits (639), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 137/372 (36%), Positives = 208/372 (55%), Gaps = 20/372 (5%) Query: 20 SSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNE-----ITYTHEQDL 74 S +++CY+++WA RP G + +I +CTH+IY+F G+ + I + D Sbjct: 5 SRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDK 64 Query: 75 RDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDG 134 ++ L+ K+ +K +A+GGW G + +S MV+ R F++SV+ FL +YNFDG Sbjct: 65 NGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFDG 124 Query: 135 LNLDWQYPGS--RGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK 192 L+LDWQYPG+ RG DK F LV+E+R+AF E ++ + + + Sbjct: 125 LDLDWQYPGAADRGGSFSDKDKFLYLVQELRRAFIREGKGWELTAAVPLANFR-----LM 179 Query: 193 SGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKD 252 GY +PEL Q LD I VM+YDL G+ +SPLYK P+D LNV+ + W+D Sbjct: 180 EGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLWED 239 Query: 253 HGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTIST----GPPGKYTDESGLLAYYEVCT 308 G + KL+VG P YG +F LS + I+ G P YT+ +G AYYE+CT Sbjct: 240 KGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYEICT 299 Query: 309 FLNEGA---TEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 ++ T+ WD + PYAY+G +WVGY++ RS ++K W+K+ GA+ W +DMD Sbjct: 300 EVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAIDMD 359 Query: 366 DFSGSFCHQRHF 377 DF G C +++ Sbjct: 360 DFQG-LCGEKNI 370 >3W4R-A nrPDB Length = 554 Score = 247 bits (630), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 138/372 (37%), Positives = 208/372 (55%), Gaps = 20/372 (5%) Query: 20 SSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNE-----ITYTHEQDL 74 S +++CY+++WA RP G + +I +CTH+IY+F G+ + I + D Sbjct: 23 SRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDK 82 Query: 75 RDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDG 134 ++ L+ K+ +K +A+GGW G + +S MV+ R F++SV+ FL +YNFDG Sbjct: 83 NGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFDG 142 Query: 135 LNLDWQYPGS--RGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK 192 L+LDW+YPG+ RG DK F LV+E+R+AF E + LT+ + Sbjct: 143 LDLDWEYPGAADRGGSFSDKDKFLYLVQELRRAFIREGKGWE-----LTAAVPLANFRLM 197 Query: 193 SGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKD 252 GY +PEL Q LD I VM+YDL G+ +SPLYK P+D LNV+ + W+D Sbjct: 198 EGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLWED 257 Query: 253 HGAASEKLIVGFPAYGHTFILSDPSKT-GIGA---PTISTGPPGKYTDESGLLAYYEVCT 308 G + KL+VG P YG +F LS + +G G P YT+ +G AYYE+CT Sbjct: 258 KGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYEICT 317 Query: 309 FLNEGA---TEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 ++ T+ WD + PYAY+G +WVGY++ RS ++K W+K+ GA+ W +DMD Sbjct: 318 EVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAIDMD 377 Query: 366 DFSGSFCHQRHF 377 DF G C +++ Sbjct: 378 DFQG-LCGEKNI 388 >5Y2C-A nrPDB Length = 383 Score = 245 bits (625), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 137/375 (36%), Positives = 205/375 (54%), Gaps = 24/375 (6%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRD----- 76 ++++CYYT+WA RP G + PG+I+P LCTH+IYAFA + E+ D Sbjct: 3 FKVVCYYTNWAWYRPDNGKYTPGDINPELCTHIIYAFAVLDKEELVIKSHDIWLDVENKF 62 Query: 77 YEALNGLKDKNTELKTLLAIGGWKFGPA-PFSAMVSTPQNRQIFIQSVIRFLRQYNFDGL 135 YE + LK +K LL +GGW +S +V+ R+ F+ + FL QY FDGL Sbjct: 63 YEKVTALKSHG--VKVLLGLGGWDDSAGDKYSRLVNNVSARRKFVVHAVDFLEQYGFDGL 120 Query: 136 NLDWQYPGS-----RGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDV 190 +LDW YP P DK F+ LVKE+RKAF +LL++ + V Sbjct: 121 DLDWLYPKCWQVECEKGPDSDKQGFADLVKELRKAFNRRG-------MLLSAAVSASKRV 173 Query: 191 IKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYW 250 I Y +P LS +LD+I +MTYD H D TG +P+Y D + NV+ ++YW Sbjct: 174 IDYAYNVPALSMNLDWISLMTYDYHGQWDKKTGHVAPMYVHDKDTDNT--FNVNFTVNYW 231 Query: 251 KDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFL 310 + GA +KL+VG P YG +F + + + TG+GAPT + G G T G L++YE+C + Sbjct: 232 INKGADRKKLVVGVPFYGQSFSVVEGAGTGLGAPTYAGGEAGDETRARGFLSFYEICERV 291 Query: 311 NEGATEVWDAP--QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFS 368 +V P + PYA ++WV +D+ + KA++++ LGG++ W LD+DDF+ Sbjct: 292 KVKGWKVHRDPGGRIGPYATHDDQWVSFDDDFMARHKAEYVRAMELGGSMAWSLDLDDFT 351 Query: 369 GSFCHQRHFPLTSTL 383 G +C PL +T+ Sbjct: 352 GKYCGCGKAPLLTTI 366 >4MNK-A nrPDB Length = 348 Score = 161 bits (408), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 111/339 (32%), Positives = 173/339 (51%), Gaps = 37/339 (10%) Query: 41 FKPGNIDPCLCTHLIYAFAGMQNNEITYT------HEQDLRDYEALNGLKDKNTELKTLL 94 F P I+ L THL YAFA + N T+ E+ D+ ++ N +KTL+ Sbjct: 18 FPPSKINSRLFTHLYYAFAEL--NAPTFEVRVPPGSEKTAEDFTPT--VRRLNPSVKTLI 73 Query: 95 AIGGWKFGPAP----FSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPK 150 +IGG G + F+ + S RQ F++S I R+Y F GL+LD++YP P Sbjct: 74 SIGG---GGSEVRDNFAKLNSDASARQRFVKSSIALARRYGFHGLDLDYEYP----EPQL 126 Query: 151 DKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDV----IKSGYKIPELSQSLDY 206 + F LV E+ A EE+ PRLLLT + + + Y + ++ LD+ Sbjct: 127 EMENFVKLVSELTAAIREEARTSGKPRLLLTEAVYFHQKLFPWEVVTEYPVQFIAAGLDW 186 Query: 207 IQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPA 266 + VM YD H + +TG + L + P + +A + ++S ++ G EKL++G P Sbjct: 187 VNVMAYDFHGSWENFTGAPAAL-RDP-NSKFTASVGIESFLA----AGMPPEKLVLGIPL 240 Query: 267 YGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPY 326 +G +++L + ++ GIGAP + GP G L++ E+ F+ GA EV+D Y Sbjct: 241 FGRSWLLKNNNEVGIGAPAVGAGP------VDGALSFSEIQNFIRGGAREVFDTTTVSAY 294 Query: 327 AYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 AY+ N WVGYDN +S LK Q+ K+ LGG W ++ D Sbjct: 295 AYKDNVWVGYDNQQSVALKVQYAKEKRLGGYFFWSVNQD 333 >3AQU-A nrPDB Length = 356 Score = 157 bits (398), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 105/333 (31%), Positives = 162/333 (48%), Gaps = 18/333 (5%) Query: 41 FKPGNIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 98 F +ID L THL AFA + Q N++T + + ++ +N +KTLL+IGG Sbjct: 16 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGG 75 Query: 99 WKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVL 158 +++M S P +R+ FI S IR R Y F GL+LDW+YP S + F L Sbjct: 76 GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----ATEMTNFGTL 131 Query: 159 VKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPK 218 ++E R A E+ PRLLL + + Y + ++ SLD++ +M YD + P Sbjct: 132 LREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPG 191 Query: 219 -DGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPS 277 TG + L+ P + G S D S W G ++K ++GFP YG+ + L++ + Sbjct: 192 WSRVTGPPAALFD-PSNAGPSGDAGTRS----WIQAGLPAKKAVLGFPYYGYAWRLTNAN 246 Query: 278 KTGIGAPTISTGPPGKYTDESGLLAYYEVCTFL-NEGATEVWDAPQEVPYAYQGNEWVGY 336 APT G G + Y ++ F+ + GAT V+++ Y Y G W+GY Sbjct: 247 SHSYYAPTT-----GAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 301 Query: 337 DNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSG 369 D+ +S K ++ K L G W + DD SG Sbjct: 302 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 334 >5GZU-A nrPDB Length = 885 Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 107/374 (28%), Positives = 174/374 (46%), Gaps = 51/374 (13%) Query: 28 YTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQ--------------- 72 + WAKD +D THL YAF + N ++ E Sbjct: 35 WVDWAKDER--------GVDATKFTHLYYAFGRINNGKVVTIKEDAKWTEDPTITEADRI 86 Query: 73 ------DLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRF 126 D + L GLK KN LK L++IGGW+ FS TP++R++F S + F Sbjct: 87 KRRNNPDESNLAYLTGLKAKNPNLKVLVSIGGWE--AEGFSDAALTPESREVFANSALDF 144 Query: 127 LRQYNFDGLNLDWQYP-----GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLT 181 + +YN DG++LDW+YP G S P+DK F+ L+K +R+ + +S + + Sbjct: 145 MNKYNLDGIDLDWEYPVYGAWGVIKSRPEDKANFTALLKLLREKLDAQSTTTN--KYYEL 202 Query: 182 STGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADL 241 + AG ++ +++ LDYI +MTYDLH D T ++ +Y + + L Sbjct: 203 AIAAGASKTYTDSVELTKITPYLDYINLMTYDLHGGWDPATSHHTAVYSA-----TNNQL 257 Query: 242 NVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLL 301 +VDS + + ++G +EKL+VG Y + + TG+ + G G + Sbjct: 258 SVDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGL------SEKAGSQAGSPGTI 311 Query: 302 AYYE-VCTFLNE-GATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVV 359 Y E V ++N+ G T WD + PY + G+ ++ Y++ S KA+++K NNL G + Sbjct: 312 VYSELVNNYINKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQNNLAGFMY 371 Query: 360 WPLDMDDFSGSFCH 373 W D S + Sbjct: 372 WEYSQDSDSHELAN 385 Score = 141 bits (356), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 100/353 (28%), Positives = 162/353 (45%), Gaps = 49/353 (13%) Query: 46 IDPCLCTHLIYAFAGMQNNEITYTHE----------QDLRD----------YEALNGLKD 85 +D TH+ YAFA +++N++ E +++R+ + L LK Sbjct: 532 VDATKLTHINYAFARIKDNKVVKISEDINWVNEFPSEEIREQRRNNPDDANFAYLKTLKQ 591 Query: 86 KNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP--- 142 +N LK L++IGGW FS TP+ R+ S I F+ QY FDG++LDW+YP Sbjct: 592 QNPSLKVLVSIGGW--AAEGFSDAALTPETREELANSAIAFMHQYGFDGIDLDWEYPVYG 649 Query: 143 --GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPEL 200 G S P+DK F+ L+K R+ + E L ++ A I + + ++ ++ Sbjct: 650 AFGVIKSRPEDKQNFTALLKLFREKLDVEGALHGKYYELAIASAAAPIYI--NSVELDKI 707 Query: 201 SQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKL 260 Q LDY+ VMTYD H + T + +Y S G D + DS+++ ++ G + KL Sbjct: 708 HQYLDYMSVMTYDYHGSWESKTAHQASVYTSALSPG---DFSADSVLTAYRKQGVPASKL 764 Query: 261 IVGFPAYGHTFILSDPSKTGIGAPTISTG---PPGKYTDESGLLAYYE-VCTFLNEGATE 316 ++G Y + + P I+ G G G Y + V + ++G T Sbjct: 765 VIGGAFYARGW---------VNVPNINHGLFQQAGDQAKNPGTPTYNDLVKDYFDKGYTR 815 Query: 317 VWDAPQEVPYAY----QGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 WD + PY Y G ++ YD+ S K KA++ K+ L G + W D Sbjct: 816 YWDNSAKAPYLYNPDANGGTFITYDDEESLKYKAEYAKNQGLRGVMFWDYSQD 868 >6BT9-A nrPDB Length = 672 Score = 151 bits (381), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 96/308 (31%), Positives = 156/308 (50%), Gaps = 21/308 (6%) Query: 76 DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGL 135 ++ L LK K LKT++++GGW + FS M + + R++F +S + FLR Y FDG+ Sbjct: 144 NFGELKRLKAKYPHLKTIISVGGWTWSNR-FSDMAADEKTRKVFAESTVAFLRAYGFDGV 202 Query: 136 NLDWQYPGSRGSP-----PKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDV 190 +LDW+YPG P P+DK F++L++++R A + E LL ++GA Sbjct: 203 DLDWEYPGVETIPGGSYRPEDKQNFTLLLQDVRNALNKAGAEDGKQYLLTIASGAS--QR 260 Query: 191 IKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYW 250 ++ ++SQ LD+I +MTYD H + + N+ LYK P D + + VD I+ + Sbjct: 261 YADHTELKKISQILDWINIMTYDFHGGWEATSNHNAALYKDPNDPAANTNFYVDGAINVY 320 Query: 251 KDHGAASEKLIVGFPAYGHTFILS--------DPSKTGIGAPTISTGPPGKY-TDESGLL 301 + G +KL++G P YG + P K G S G Y T ++G+ Sbjct: 321 TNEGVPVDKLVLGVPFYGRGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVY 380 Query: 302 AYYEV-CTFLNE-GATEVWDAPQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGA 357 Y ++ ++N+ G W+ +VPY Y ++ YD+ S K K ++K L GA Sbjct: 381 DYGDLAANYVNKNGFVRYWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGA 440 Query: 358 VVWPLDMD 365 + W L D Sbjct: 441 MFWELSGD 448 >1ITX-A nrPDB Length = 419 Score = 148 bits (373), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 118/434 (27%), Positives = 197/434 (45%), Gaps = 82/434 (18%) Query: 16 VQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFA-----GMQNNE----- 65 + SY+++ YY SWA ++ +IDP TH+ YAFA G+ N Sbjct: 6 AEAADSYKIVGYYPSWAA---YGRNYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGP 62 Query: 66 --ITYTHEQDLR----------------------------------DYEALNGLKDKNTE 89 +T+T + + + LN LK N Sbjct: 63 NPVTWTCQNEKSQTINVPNGTIVLGDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPN 122 Query: 90 LKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRG--- 146 LKT++++GGW + FS + +T R++F S + FLR+YNFDG++LDW+YP S G Sbjct: 123 LKTIISVGGWTWSNR-FSDVAATAATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDG 181 Query: 147 --SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSL 204 P+DK +++L+ ++R+ + LL ++GA + ++ +++ + Sbjct: 182 NSKRPEDKQNYTLLLSKIREKLDAAGAVDGKKYLLTIASGASA--TYAANTELAKIAAIV 239 Query: 205 DYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSA----DLNVDSIISYWKDH---GAAS 257 D+I +MTYD + + N+PL YD SA D N ++ + + H G + Sbjct: 240 DWINIMTYDFNGAWQKISAHNAPL---NYDPAASAAGVPDANTFNVAAGAQGHLDAGVPA 296 Query: 258 EKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEV-CTFLNE-GAT 315 KL++G P YG + ++ G G TG T E+G +Y++ ++N+ G T Sbjct: 297 AKLVLGVPFYGRGW--DGCAQAGNGQYQTCTGGSSVGTWEAGSFDFYDLEANYINKNGYT 354 Query: 316 EVWDAPQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCH 373 W+ +VPY Y + ++ YD+ S K ++K LGGA+ W L D Sbjct: 355 RYWNDTAKVPYLYNASNKRFISYDDAESVGYKTAYIKSKGLGGAMFWELSGD-------- 406 Query: 374 QRHFPLTSTLKGDL 387 R+ L + LK DL Sbjct: 407 -RNKTLQNKLKADL 419 >3ALF-A nrPDB Length = 353 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 96/326 (29%), Positives = 152/326 (46%), Gaps = 17/326 (5%) Query: 45 NIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFG 102 NID L THL AFA + Q N++ + E + + ++ KN +KT L+I G + Sbjct: 19 NIDSTLFTHLFCAFADLNPQLNQLIISPENQDSFRQFTSTVQRKNPSVKTFLSIAGGRAN 78 Query: 103 PAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEM 162 + M P +R+ FI S IR RQ F GL+LDW+YP S D L+ E Sbjct: 79 STAYGIMARQPNSRKSFIDSSIRLARQLGFHGLDLDWEYPLS----AADMTNLGTLLNEW 134 Query: 163 RKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPK--DG 220 R A E+ LLLT+ + V Y + L+++LD+I +M YD + P Sbjct: 135 RTAINTEARNSGRAALLLTAAVSNSPRVNGLNYPVESLARNLDWINLMAYDFYGPNWSPS 194 Query: 221 YTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTG 280 T ++ L+ + S +N W G ++KL++G P YG+ + L + + G Sbjct: 195 QTNSHAQLFDPVNHVSGSDGINA------WIQAGVPTKKLVLGIPFYGYAWRLVNANIHG 248 Query: 281 IGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG-ATEVWDAPQEVPYAYQGNEWVGYDNV 339 + AP G D G + Y + ++ E AT V++A Y Y G+ W+ YD+ Sbjct: 249 LRAPAAGKSNVGAVDD--GSMTYNRIRDYIVESRATTVYNATIVGDYCYSGSNWISYDDT 306 Query: 340 RSFKLKAQWLKDNNLGGAVVWPLDMD 365 ++ + K ++K L G W + D Sbjct: 307 QTVRNKVNYVKGRGLLGYFAWHVAGD 332 >4URI-A nrPDB Length = 337 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 105/331 (31%), Positives = 152/331 (45%), Gaps = 35/331 (10%) Query: 45 NIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGW--K 100 +I+P THL AFA + N++T + ++ KN +KTLL+IGG + Sbjct: 17 DINPSHFTHLFCAFADLDPNTNKLTISSSNAAAFSTFTQTVRAKNPSVKTLLSIGGGGGR 76 Query: 101 FGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVK 160 A F+ M S R+ FI S I+ R+ NF GL+LDW+YP S DK F+ L++ Sbjct: 77 ALAAVFANMASQASRRKSFIDSSIQLARRNNFHGLDLDWEYPSSD----IDKTNFASLIR 132 Query: 161 EMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPE-LSQSLDYIQVMTYDLHDPKD 219 E R A ES P LLL++ G + Y E ++ +LD++ VMTYDL Sbjct: 133 EWRAAVATESSTSGTPALLLSAAVGGSDQITPLKYYPGEAIANNLDWVNVMTYDL----- 187 Query: 220 GYTGENSPLYKSP-----YDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILS 274 YT ++ P P Y G + D I+ W G KL +G P YG + LS Sbjct: 188 -YTSDSYPTLTQPPAPLFYPRGI---FSADEGITKWIQSGVPESKLALGLPFYGFKWRLS 243 Query: 275 DPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWV 334 DP+ G+ AP KY D +N G +D+ Y ++G +W Sbjct: 244 DPNNHGLFAPATQGLGAVKYKD------------IVNTGGQVEFDSTYVTNYRFKGTDWY 291 Query: 335 GYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 GYD+ +S K + K L G W ++ D Sbjct: 292 GYDDTQSISAKVAYAKQRGLFGYFAWHIEQD 322 >3WD0-A nrPDB Length = 503 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 101/390 (25%), Positives = 166/390 (42%), Gaps = 69/390 (17%) Query: 41 FKPGNIDPCLC---THLIYAFAGMQNN-EITY---THEQDLRDY-EALNGLKDKNTELKT 92 F NI P TH+ ++F + +N E + T++ RD L LK N L+ Sbjct: 35 FPVSNITPAKAKQLTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTALKAHNPSLRI 94 Query: 93 LLAIGGWKFGP------APFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRG 146 + +IGGW + A + V TP R F QS +R ++ Y FDG+++DW+YP + Sbjct: 95 MFSIGGWYYSNDLGVSHANYVNAVKTPAARTKFAQSCVRIMKDYGFDGVDIDWEYPQA-- 152 Query: 147 SPPKDKHLFSVLVKEMRKAFEEESV---EKDIPRLLLTSTGAGIIDVIKSGYKIPELSQS 203 + F ++E+R ++++ + +P L + G + + K+ ++ Sbjct: 153 ---AEVDGFIAALQEIRTLLNQQTIADGRQALPYQLTIAGAGGAFFLSRYYSKLAQIVAP 209 Query: 204 LDYIQVMTYDLHDPKDGYTGENSPLYKSP-----YDIGKSAD-----------------L 241 LDYI +MTYDL P + T + L+ Y+ + A+ L Sbjct: 210 LDYINLMTYDLAGPWEKITNHQAALFGDAAGPTFYNALREANLGWSWEELTRAFPSPFSL 269 Query: 242 NVDSII-SYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGK------- 293 VD+ + + G S K+++G P YG F G G S PG+ Sbjct: 270 TVDAAVQQHLMMEGVPSAKIVMGVPFYGRAF---KGVSGGNGGQYSSHSTPGEDPYPNAD 326 Query: 294 ---------YTDESGLLAYYEVCTFL---NEGATEVWDAPQEVPYAY--QGNEWVGYDNV 339 D+ +A Y + N G +W+ + PY Y Q +V YD+ Sbjct: 327 YWLVGCDECVRDKDPRIASYRQLEQMLQGNYGYQRLWNDKTKTPYLYHAQNGLFVTYDDA 386 Query: 340 RSFKLKAQWLKDNNLGGAVVWPLDMDDFSG 369 SFK KA+++K LGG + W L D+ +G Sbjct: 387 ESFKYKAKYIKQQQLGGVMFWHLGQDNRNG 416 >6EPB-A nrPDB Length = 423 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 97/367 (26%), Positives = 162/367 (44%), Gaps = 44/367 (11%) Query: 22 YQLMCYYTSWA-KDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEA- 79 Y Y+T+W DR +F+P ++ TH+IY+F +Q + + + DYE Sbjct: 38 YANSVYFTNWGIYDR----NFQPADLVASDVTHVIYSFMNLQADGTVISGDT-YADYEKH 92 Query: 80 -------------------LNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFI 120 L +K N LK LL+IGGW + F + ST NR+ F Sbjct: 93 YADDSWNDVGTNAYGCVKQLFKVKKANRGLKVLLSIGGWTW-STNFPSAASTDANRKNFA 151 Query: 121 QSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLL 180 ++ I F++ + FDG+++DW+YP +L+KE+R + + + L Sbjct: 152 KTAITFMKDWGFDGIDIDWEYPADATQASN----MILLLKEVRSQLDAYAAQYAPGYHFL 207 Query: 181 TSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSAD 240 + A S ++ +L Q LDYI +M YD TG ++ L+ +P + + Sbjct: 208 LTIAAPAGKDNYSKLRLADLGQVLDYINLMAYDYAGSFSPLTGHDANLFNNPSNP-NATP 266 Query: 241 LNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGL 300 N DS + + + G + K+++G P YG +F + GIG G G + E+G+ Sbjct: 267 FNTDSAVKDYINGGVPANKIVLGMPIYGRSF----QNTAGIGQTYNGVG-SGSW--EAGI 319 Query: 301 LAYYEVCTFLNEGATEVWDAPQEVPYAYQG--NEWVGYDNVRSFKLKAQWLKDNNLGGAV 358 Y + GAT +D+ + Y+Y E + +D K +LK LGG++ Sbjct: 320 WDYKALP---KAGATVQYDSVAKGYYSYNSATKELISFDTPDMINTKVAYLKSLGLGGSM 376 Query: 359 VWPLDMD 365 W D Sbjct: 377 FWEASAD 383 >6F8N-A nrPDB Length = 414 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 105/377 (27%), Positives = 168/377 (44%), Gaps = 62/377 (16%) Query: 46 IDPCLCTHLIYAFAGMQNNEI---------------TYTHEQDLRDYEALNGLKDKNTEL 90 +D THL Y+F + N+E Y + + D + L L+ +N EL Sbjct: 34 LDVTQITHLNYSFGLIYNDEKQETNPALKDPSRLHQIYLSPKVMADLQLLPVLRKQNPEL 93 Query: 91 KTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP-----GSR 145 K LL++GGW G FS +T ++R +FI+SV + ++QY+ DG++LDWQYP G Sbjct: 94 KVLLSVGGW--GARGFSGAAATAESRAVFIRSVQQVIKQYHLDGIDLDWQYPVNGAWGLV 151 Query: 146 GSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLD 205 S P D+ F++L+ E+ KA D +LL + GA + + + ++ LD Sbjct: 152 ESQPADRANFTLLLAELHKAL-------DKGKLLTIAVGAN-VKSPQEWVDVKGIAPYLD 203 Query: 206 YIQVMTYDLHDPKDGYTGENSPLYKSPY--DIGKSADLNVDSIISYWKDHGAASEKLIVG 263 YI +MTYD+ G NS LY S + + + + ++ + G +L +G Sbjct: 204 YINLMTYDM---AYGTQYFNSNLYDSKQWPTVAAADRYSANFVVDNYLAAGLKPAQLNLG 260 Query: 264 FPAYGHT----------FILSDPSKTGIGAPTISTGPPGKY-------TDESGLLAYYEV 306 YG + +D +K + P + + T +S V Sbjct: 261 IGFYGRVPKRATEPGIDWDKADAAKNPVTQPYFTARETAVFKAMGLDLTKDSYFKYNDIV 320 Query: 307 CTFLNEGA---TEVWDAPQEVPY----AYQGNEW--VGYDNVRSFKLKAQWLKDNNLGGA 357 LN+ T WD+ +VPY + +G + Y+N RS LKA ++K LGGA Sbjct: 321 SKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKPLFAISYENPRSVALKADYIKSKGLGGA 380 Query: 358 VVWPLDMDDFSGSFCHQ 374 + W DD + HQ Sbjct: 381 MFWEYGADD-NNRLAHQ 396 >5ZL9-A nrPDB Length = 618 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 99/353 (28%), Positives = 172/353 (48%), Gaps = 31/353 (8%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + IEGSF+ G D + H +A +T + ++ L LK + Sbjct: 182 KEIEGSFQALQRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHP 241 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPGSRGS 147 +LK L +IGGW PF M + R F+ SV FL+ + F DG+++DW++PG +G+ Sbjct: 242 DLKILPSIGGWTLSD-PFFFMGDKVK-RDRFVGSVKEFLQTWKFFDGVDIDWEFPGGKGA 299 Query: 148 -----PPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 P+D + +L+KE+R ++ SVE L ++ AG D I Y ++Q Sbjct: 300 NPNLGSPQDGETYVLLMKELRAMLDQLSVETGRKYELTSAISAGK-DKIDKFYSFVNVAQ 358 Query: 203 -SLDYIQVMTYDLHDPKD----GY-TGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAA 256 S+D+I +M+YD + D G+ T N+P +K D + V+++++ G Sbjct: 359 NSMDHIFLMSYDFYGAFDLKNLGHQTALNAPAWKP--DTAYTTVNGVNALLA----QGVK 412 Query: 257 SEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVC-TFLNEGAT 315 K++VG YG + + + I +TGP K T E+G++ Y ++ F++ Sbjct: 413 PGKIVVGTAMYGRGWTGVNGYQNNIPFTGTATGPV-KGTWENGIVDYRQIAGQFMSGEWQ 471 Query: 316 EVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 +DA E PY ++ + + +D+ RS + K +++ D LGG W +D D+ Sbjct: 472 YTYDATAEAPYVFKPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSWEIDADN 524 >1JNE-A nrPDB Length = 420 Score = 111 bits (277), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 107/418 (25%), Positives = 181/418 (43%), Gaps = 59/418 (14%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCL--CTHLIYAFAGMQNNEI-TYTHEQDLRDYE- 78 L+CYY S + R G +++ L C+HL+Y +AG++ + Y+ ++L Y+ Sbjct: 3 NLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKH 62 Query: 79 ---ALNGLKDKNTELKTLLAIGGWKF----GPAPFSAMVSTPQNRQI-FIQSVIRFLRQY 130 + LK K LK LL++GG P + ++ + RQI FI+S ++ Y Sbjct: 63 QFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYELVKTY 122 Query: 131 NFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESV---EKDIPRLLLTSTGAGI 187 FDGL+L +Q+P + P K + K ++K F + + + + T+ + Sbjct: 123 GFDGLDLAYQFP--KNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDV 180 Query: 188 IDVIKSG-----------------YKIPELSQSLDYIQVMTYDLHDPKDG--YTGENSPL 228 D +++ + IP L+ +D++ + T+D P ++P+ Sbjct: 181 KDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPI 240 Query: 229 YKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILS-DPSKTGIGAPTIS 287 Y + A LN D + YW G S K+ +G YG+ + L+ D G+ + Sbjct: 241 YHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPET 300 Query: 288 TGPP--GKYTDESGLLAYYEVCTFL----------NEGATEVWDAPQE-------VPYAY 328 +GP G + + GLL+Y E+C L NE P + P Sbjct: 301 SGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDG 360 Query: 329 QGNE--WVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLK 384 Q E WV YD+ S KA + + NLGG ++ L DDF G C +P+ +K Sbjct: 361 QITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPILRAIK 417 >3G6L-A nrPDB Length = 406 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 96/365 (26%), Positives = 157/365 (43%), Gaps = 48/365 (13%) Query: 26 CYYTSWAKDRPIEG-SFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQ--DLRDY----- 77 Y+T+W I G +F+P ++ H++Y+F ++ + Y+ + DL + Sbjct: 25 VYFTNWG----IYGRNFQPADLQASKILHVLYSFMNLRVDGTVYSGDTYADLEKHYSDDS 80 Query: 78 ------------EALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIR 125 + L LK N LK +L+IGGW + F A ST R F ++ + Sbjct: 81 WNDIGTNAYGCVKQLYKLKKANRSLKIMLSIGGWTW-STNFPAAASTEATRATFAKTAVE 139 Query: 126 FLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGA 185 F++ + FDG+++DW+YP S D + +L++ +R+ + S S A Sbjct: 140 FMKDWGFDGIDVDWEYPASE----TDANNMVLLLQRVRQELDSYSATYANGYHFQLSIAA 195 Query: 186 GIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKS---PYDIGKSADLN 242 + K+ +L LD I +M YD D +G + LY S P S Sbjct: 196 PAGPSHYNVLKLAQLGSVLDNINLMAYDYAGSWDSVSGHQTNLYPSTSNPSSTPFSTKAA 255 Query: 243 VDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLA 302 VD+ I+ G + K+I+G P YG F+ +D G G P + G G + ESG+ Sbjct: 256 VDAYIA----AGVPASKIILGMPIYGRAFVGTD----GPGKPYSTIG-EGSW--ESGIWD 304 Query: 303 YYEVCTFLNEGATEVWDAPQEVPYAYQGNE--WVGYDNVRSFKLKAQWLKDNNLGGAVVW 360 Y GAT + D+ Y+Y + + YD + K + K LGG++ W Sbjct: 305 Y---KVLPKAGATVITDSAAGATYSYDSSSRTMISYDTPDMVRTKVSYAKGLGLGGSMFW 361 Query: 361 PLDMD 365 D Sbjct: 362 EASAD 366 >3CHF-A nrPDB Length = 433 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 101/371 (27%), Positives = 167/371 (45%), Gaps = 45/371 (12%) Query: 14 LNVQLGSSYQLMCYYTSWAKDRPIEG-SFKPGNIDPCLCTHLIYAFAGM--QNNEITYTH 70 L + S Y+ + Y+ +WA I G + P ++ TH++YAFA + + E+ T Sbjct: 35 LEARASSGYRSVVYFVNWA----IYGRNHNPQDLPVERLTHVLYAFANVRPETGEVYMTD 90 Query: 71 E-QDLRDY-----------------EALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVST 112 D+ + + L LK +N LK LL+IGGW + P F+ ST Sbjct: 91 SWADIEKHYPGDSWSDTGNNVYGCIKQLYLLKKQNRNLKVLLSIGGWTYSPN-FAPAAST 149 Query: 113 PQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEES-V 171 R+ F ++ ++ L+ FDGL++DW+YP + + + F +L+KE+R A + S Sbjct: 150 DAGRKNFAKTAVKLLQDLGFDGLDIDWEYPEND----QQANDFVLLLKEVRTALDSYSAA 205 Query: 172 EKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKS 231 LLT D IK + ++ Q LD+ +M YD +G + +Y Sbjct: 206 NAGGQHFLLTVASPAGPDKIKV-LHLKDMDQQLDFWNLMAYDYAGSFSSLSGHQANVYND 264 Query: 232 PYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPP 291 + S N + + ++ G + K+++G P YG +F +D G G P G Sbjct: 265 TSNP-LSTPFNTQTALDLYRAGGVPANKIVLGMPLYGRSFANTD----GPGKPYNGVG-Q 318 Query: 292 GKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNE--WVGYDNVRSFKLKAQWL 349 G + E+G+ Y + GATE Y+Y + YDN + LK+ ++ Sbjct: 319 GSW--ENGVWDYKALP---QAGATEHVLPDIMASYSYDATNKFLISYDNPQVANLKSGYI 373 Query: 350 KDNNLGGAVVW 360 K LGGA+ W Sbjct: 374 KSLGLGGAMWW 384 >5GQB-A nrPDB Length = 553 Score = 107 bits (268), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 94/348 (27%), Positives = 160/348 (45%), Gaps = 23/348 (6%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + IEGSF+ G D + H +A ++ +E ++ L LK Sbjct: 198 KEIEGSFQALQRSCSGREDFKVSIHDPWAALQKPQKGLSSWNEPYKGNFGQLMMLKQAKP 257 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPGSRGS 147 +LK L +IGGW PF + R+ F+ SV FL+ + F DG+++DW++PG +G+ Sbjct: 258 DLKILPSIGGWTLAD-PFFFFTDETKRRR-FVASVKDFLQTWKFFDGVDIDWEFPGGKGA 315 Query: 148 -----PPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 PKD ++ +L+KE+R+ E S E L ++ AG + Y + + Sbjct: 316 NPNLGSPKDGEIYVLLMKELREMLNELSAETGRKYELTSAISAGWDKIQVVDYSAAQ--K 373 Query: 203 SLDYIQVMTYDLHDPKDGYT-GENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 +D+I M+YD T G + LY D + D + + G + +K++ Sbjct: 374 YMDHIFFMSYDFKGAWSNDTLGHQASLYAP--DWNEKETYTTDFGVQFLLAQGVSPKKIV 431 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEV-WDA 320 VG YG + K +TGP K T + G++ Y E+ T + +G E +D Sbjct: 432 VGVAMYGRGWTGVHGYKDNNPFTGNATGPV-KGTWQDGVVDYREIATEIAQGKWEYHYDK 490 Query: 321 PQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 + PY ++ + + YD+ RS K ++++ N LGG W +D D+ Sbjct: 491 VAQAPYVFRPATGDLITYDDARSTIEKGKYVRANKLGGLFAWEIDADN 538 >5Z7M-A nrPDB Length = 546 Score = 107 bits (267), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 95/352 (26%), Positives = 169/352 (48%), Gaps = 31/352 (8%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + IEGSF+ G D + H +A +T + ++ L LK + Sbjct: 182 KEIEGSFQALQRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHP 241 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPGSRGS 147 +LK L +IGGW PF M + R F+ SV FL+ + F DG+++ W++PG +G+ Sbjct: 242 DLKILPSIGGWTLSD-PFFFMGDKVK-RDRFVGSVKEFLQTWKFFDGVDIAWEFPGGKGA 299 Query: 148 -----PPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 P+D + +L+KE+R ++ SVE L ++ AG + K Y + + Sbjct: 300 NPNLGSPQDGETYVLLMKELRAMLDQLSVETGRKYELTSAISAGKDMIDKVAYNVAQ--N 357 Query: 203 SLDYIQVMTYDLHDPKD----GY-TGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAAS 257 S+D+I +M+YD + D G+ T N+P +K D + V+++++ G Sbjct: 358 SMDHIFLMSYDFYGAADLKNLGHQTALNAPAWKP--DTAYTTVNGVNALLA----QGVKP 411 Query: 258 EKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVC-TFLNEGATE 316 K++VG YG + + + I +TGP K T E+G++ Y ++ F++ Sbjct: 412 GKIVVGTAMYGRGWTGVNGYQNNIPFTGTATGPV-KGTWENGIVDYRQIAGQFMSGEWQY 470 Query: 317 VWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 +DA E PY ++ + + +D+ RS + K +++ D LGG +D D+ Sbjct: 471 TYDATAEAPYVFKPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSAMIDADN 522 >3QOK-A nrPDB Length = 420 Score = 106 bits (265), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 102/374 (27%), Positives = 164/374 (43%), Gaps = 71/374 (18%) Query: 46 IDPCLCTHLIYAFAGMQNNEITYT----------HEQDLR-----DYEALNGLKDKNTEL 90 +D THL Y+F + N+E T HE L D + L L+ +N +L Sbjct: 49 LDVRQITHLNYSFGLIYNDEKDETNAALKDPAHLHEIWLSPKVQADLQKLPALRKQNPDL 108 Query: 91 KTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP-----GSR 145 K LL++GGW G FS +T ++R +FI+S + ++QY DG++LDW++P G Sbjct: 109 KVLLSVGGW--GARGFSGAAATAESRAVFIRSAQKIIQQYGLDGIDLDWEFPVNGAWGLV 166 Query: 146 GSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLD 205 S P D+ F+ L+K +R+A E+ +L+ + GA + KS + ++ L+ Sbjct: 167 ASQPADRDNFTALLKSLREAVGEQ-------KLVTIAVGAN-AESPKSWVDVKAVAPVLN 218 Query: 206 YIQVMTYDLHDPKDGYTGENSPLYKSPY--DIGKSADLNVDSIISYWKDHGAASEKLIVG 263 YI +MTYD+ G NS LY S + + + + D +++ + G ++ +G Sbjct: 219 YINLMTYDM---AYGTQYFNSNLYDSSHWPTVAAADKYSADFVVNNYLAAGLKPSQMNLG 275 Query: 264 FPAYGHT----------FILSDPSKTGIGAP---------------TISTGPPGKYTDES 298 YG + +D + P +S KY D Sbjct: 276 IGFYGRVPKRAVEPGIDWTKADAQNNPVTQPYFGPQQIALFASLGYDLSKDTYVKYNDIV 335 Query: 299 GLLAYYEVCTFLNEGATEVWDAPQEVPY-AYQGNE-----WVGYDNVRSFKLKAQWLKDN 352 G L F TE WD +VP+ + Q E + Y+N RS +KA ++K Sbjct: 336 GKLLNDPQKRF-----TEHWDDEAKVPWLSVQSAEGKPLFALSYENPRSVAIKADYIKAK 390 Query: 353 NLGGAVVWPLDMDD 366 L GA+ W DD Sbjct: 391 GLAGAMFWEYGADD 404 >1LL6-A nrPDB Length = 392 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 98/368 (26%), Positives = 167/368 (45%), Gaps = 46/368 (12%) Query: 22 YQLMCYYTSWAKDRPIEG-SFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQ-------- 72 ++ + Y+ +WA I G P ++ TH++YAFA ++ + Y + Sbjct: 3 FRSVVYFVNWA----IYGRGHNPQDLKADQFTHILYAFANIRPSGEVYLSDTWADTDKHY 58 Query: 73 --DLRDYEALNG---------LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQ 121 D D N LK N LKTLL+IGGW + P F ST + R+ F Sbjct: 59 PGDKWDEPGNNVYGCIKQMYLLKKNNRNLKTLLSIGGWTYSPN-FKTPASTEEGRKKFAD 117 Query: 122 SVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEK-DIPRLLL 180 + ++ ++ FDG++++W+YP K + F +L+K R+A + S + + + LL Sbjct: 118 TSLKLMKDLGFDGIDINWEYP----EDEKQANDFVLLLKACREALDAYSAKHPNGKKFLL 173 Query: 181 T-STGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSA 239 T ++ AG + K K+ E+ + LD+ +M YD D +G S ++ S +S Sbjct: 174 TIASPAGPQNYNK--LKLAEMDKYLDFWNLMAYDFSGSWDKVSGHMSNVFPSTTKP-EST 230 Query: 240 DLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESG 299 + D + + G + K+++G P YG F +D GIG S G + E+G Sbjct: 231 PFSSDKAVKDYIKAGVPANKIVLGMPLYGRAFASTD----GIGT---SFNGVGGGSWENG 283 Query: 300 LLAYYEVCTFLNEGA--TEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGA 357 + Y ++ +GA TE+ D Y + YD V+ KA+++ N +GG Sbjct: 284 VWDYKDMP---QQGAQVTELEDIAASYSYDKNKRYLISYDTVKIAGKKAEYITKNGMGGG 340 Query: 358 VVWPLDMD 365 + W D Sbjct: 341 MWWESSSD 348 >5XWF-A nrPDB Length = 378 Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 91/341 (26%), Positives = 163/341 (47%), Gaps = 35/341 (10%) Query: 53 HLIYAFAG-MQNNEITYTHEQDLRDYEALNGLKDKNTELKTL-LAIGGWKFGPAPFSAMV 110 H++YAFA ++ E++ + L+ +++ ++ K++ L++GGW G FS ++ Sbjct: 24 HIVYAFAEPTKDGELSGFTDSQLKSV-----VQEAHSRGKSISLSVGGWT-GSLYFSDLL 77 Query: 111 STPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGS---RGSPPKDKHLFSVLVKEMRKAFE 167 + + F+ +++ +++Y+ DGLNLDW+YP S KD++ + +K + KA Sbjct: 78 KSSSSFDNFVSNLVDVVKEYDLDGLNLDWEYPNSPNGVACNSKDENDTANYLK-LFKALR 136 Query: 168 EESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSP 227 E+ K I + + + S + ++D +M YD++ +D G N+P Sbjct: 137 EKLGSKTILTTAVPTAPFNDENQQPSTKLDDNWASTVDAFYIMAYDVNGIRDKNAGANAP 196 Query: 228 LYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDP--SKTGIGAP- 284 LY SP G D++ + W G +E+L++G P YG +P + TG+ P Sbjct: 197 LYYSPKVTGVEPTSGNDAVKA-WIAAGIPAEQLVLGVPFYGRVSKTLEPITASTGLYVPI 255 Query: 285 TISTGPPGKYTDE-------SGLLAY---YEVCTFLNEGATE-------VWDAPQEVPYA 327 + S+ G TDE + + Y Y T EG WD + PYA Sbjct: 256 SQSSQIKGDSTDEKAADPCPNAVATYSGQYIWRTIAQEGIARNSSGWVTYWDDISKTPYA 315 Query: 328 Y--QGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 Y G++ + +D+ S + K + K LGG ++W L+MDD Sbjct: 316 YSFSGSKVLSFDDAASLQDKVDYAKKQGLGGVMLWSLEMDD 356 >1KFW-A nrPDB Length = 435 Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 84/320 (26%), Positives = 133/320 (41%), Gaps = 47/320 (14%) Query: 77 YEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYN----- 131 + L LK KN +LK ++++GGW + FS +T +RQ + S I + N Sbjct: 105 FNQLKQLKAKNPKLKVMISLGGWTW-SKNFSKAAATEASRQKLVSSCIDLYIKGNLPNFE 163 Query: 132 -----------FDGLNLDWQYPGSRGS-------PPKDKHLFSVLVKEMRKAFEEESVEK 173 FDG+++DW++PG+ D+ F L+ E RK + Sbjct: 164 GRGGAGAAAGIFDGIDIDWEWPGTNSGLAGNGVDTVNDRANFKALLAEFRKQLDAYGSTN 223 Query: 174 DIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKD-GYTGENSPLYKSP 232 + +L A D+ G+ P +SLD+ + YDLH + TG + LY P Sbjct: 224 NKKYVLSAFLPANPADIDAGGWDDPANFKSLDFGSIQGYDLHGAWNPTLTGHQANLYDDP 283 Query: 233 YD-IGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTIS---- 287 D S + D + + G ++L +G AYG + GA +S Sbjct: 284 ADPRAPSKKFSADKAVKKYLAAGIDPKQLGLGLAAYGRGWT---------GAKNVSPWGP 334 Query: 288 --TGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLK 345 G PG Y E+ Y ++ T T+ +DA + Y G +W YDN+ + K K Sbjct: 335 ATDGAPGTY--ETANEDYDKLKTL----GTDHYDAATGSAWRYDGTQWWSYDNIATTKQK 388 Query: 346 AQWLKDNNLGGAVVWPLDMD 365 ++ LGG + W L D Sbjct: 389 TDYIVSKGLGGGMWWELSGD 408 >3ARQ-A nrPDB Length = 584 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 88/329 (26%), Positives = 141/329 (42%), Gaps = 42/329 (12%) Query: 76 DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DG 134 +Y L LK +N +LK + +IGGW PF V +NR F+ SV +FL+ + F DG Sbjct: 231 NYAMLMALKQRNPDLKIIPSIGGWTLSD-PFYDFVDK-KNRDTFVASVKKFLKTWKFYDG 288 Query: 135 LNLDWQYP------GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 +++DW++P +G P D + L++E+R +E E L ++ G G Sbjct: 289 VDIDWEFPGGGGAAADKGDPVNDGPAYIALMRELRVMLDELEAETGRTYELTSAIGVGYD 348 Query: 189 DVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPY------DIG------ 236 + Y + Q +DYI MTYD + + G + LY + D G Sbjct: 349 KIEDVDYA--DAVQYMDYIFAMTYDFYGGWNNVPGHQTALYCGSFMRPGQCDGGGVDENG 406 Query: 237 ---KSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTF------ILSDPSKTGIGAPTIS 287 K D+ I G + KL++G YG + L+DP+ G T Sbjct: 407 EPYKGPAYTADNGIQLLLAQGVPANKLVLGTAMYGRGWEGVTPDTLTDPNDPMTGTATGK 466 Query: 288 -TGPPGKYTDESGLLAYYEVCTFL----NEGATEV---WDAPQEVPYAYQGN--EWVGYD 337 G + E G++ Y + +F+ N G +DA E P+ + + E + +D Sbjct: 467 LKGSTAQGVWEDGVIDYKGIKSFMLGANNTGINGFEYGYDAQAEAPWVWNRSTGELITFD 526 Query: 338 NVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 + RS K + K L G W +D D+ Sbjct: 527 DHRSVLAKGNYAKSLGLAGLFSWEIDADN 555 >4DWS-C nrPDB Length = 546 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 76/298 (25%), Positives = 130/298 (43%), Gaps = 29/298 (9%) Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY-NFDGLNLDWQYPGSRG- 146 +L +IGGW + FSA+ P R++F+ SV+ F ++ F +++DW+YPG G Sbjct: 211 KLDLAFSIGGWSL-SSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGD 269 Query: 147 ----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 S KD + +L+KE+R A + + + + +G +K+ K + Q Sbjct: 270 EGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIACSG------VKAKLKKSNIDQ 323 Query: 203 ----SLDYIQVMTYDLHDPK-DGYTGENSPLYKSPYDIGKSA--DLNVDSIISYWKDH-G 254 LD I +M+YD Y G ++ LY SP D G+ DL+ ++ I Y + G Sbjct: 324 LVANGLDNIYLMSYDFFGTIWADYIGHHTNLY-SPKDPGEQELFDLSAEAAIDYLHNELG 382 Query: 255 AASEKLIVGFPAYGHTFILSDP-----SKTGIGAPTISTGPPGKYTDESGLLAYYEVCTF 309 EK+ +G+ YG + + D +K G T+ G P + + + Sbjct: 383 IPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSM 442 Query: 310 LNEGATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 G + D + + + ++ D R+ K K ++ N LGG W D D Sbjct: 443 GKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD 500 >6OGD-C nrPDB Length = 633 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 76/298 (25%), Positives = 130/298 (43%), Gaps = 29/298 (9%) Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY-NFDGLNLDWQYPGSRG- 146 +L +IGGW + FSA+ P R++F+ SV+ F ++ F +++DW+YPG G Sbjct: 298 KLDLAFSIGGWSL-SSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGD 356 Query: 147 ----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 S KD + +L+KE+R A + + + + +G +K+ K + Q Sbjct: 357 EGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIACSG------VKAKLKKSNIDQ 410 Query: 203 ----SLDYIQVMTYDLHDPK-DGYTGENSPLYKSPYDIGKSA--DLNVDSIISYWKDH-G 254 LD I +M+YD Y G ++ LY SP D G+ DL+ ++ I Y + G Sbjct: 411 LVANGLDNIYLMSYDFFGTIWADYIGHHTNLY-SPKDPGEQELFDLSAEAAIDYLHNELG 469 Query: 255 AASEKLIVGFPAYGHTFILSDP-----SKTGIGAPTISTGPPGKYTDESGLLAYYEVCTF 309 EK+ +G+ YG + + D +K G T+ G P + + + Sbjct: 470 IPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSM 529 Query: 310 LNEGATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 G + D + + + ++ D R+ K K ++ N LGG W D D Sbjct: 530 GKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD 587 >5DF0-A nrPDB Length = 545 Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 87/355 (24%), Positives = 156/355 (43%), Gaps = 38/355 (10%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + I GSF+ G D + H +A ++ +E ++ L K N Sbjct: 195 KTISGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKSVSAWNEPYKGNFGQLMAAKLANP 254 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPGSRGS 147 LK L +IGGW PF M + R +F+ SV FL+ + F DG+++DW++PG +G+ Sbjct: 255 HLKILPSIGGWTLSD-PFYFMHDV-EKRNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGA 312 Query: 148 PP------KDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 P +D + +L++E+R ++ + L ++ AG + Y E Sbjct: 313 NPSLGDAERDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNY--AEAQ 370 Query: 202 QSLDYIQVMTYDLHDP-KDGYTGENSPLYKSPYDIGK--SADLNVDSIISYWKDHGAASE 258 +SL I +M+YD + G + +Y ++ + + VD+++ G Sbjct: 371 KSLGKIFLMSYDFKGAWSNTDLGYQTTVYAPSWNSEELYTTHYAVDALLK----QGVDPN 426 Query: 259 KLIVGFPAYGH-----TFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG 313 K+IVG YG T +D +G G +S T E G++ Y ++ LN Sbjct: 427 KIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPVSG------TWEDGVVDYRQIQKDLNN- 479 Query: 314 ATEVWDAPQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 +D+ + Y + + + + +D+V S K +++ N LGG W +D D+ Sbjct: 480 YVYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADN 534 >4A5Q-A nrPDB Length = 546 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 81/332 (24%), Positives = 138/332 (41%), Gaps = 52/332 (15%) Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY-NFDGLNLDWQY 141 L + + EL+ L+IGGW FS + R F++ + F +++ F L++DW+Y Sbjct: 203 LHEADKELEFSLSIGGWSMS-GLFSEIAKDEILRTNFVEGIKDFFQRFPMFSHLDIDWEY 261 Query: 142 PGSRGS----PPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKI 197 PGS G+ P D F++L++++ A I L S + I Sbjct: 262 PGSIGAGNPNSPDDGANFAILIQQITDA--------KISNLKGISIASSADPAKIDAANI 313 Query: 198 PELSQS-LDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAA 256 P L + + I +MTYD DG ++ +Y+ P D+ + ++D +++ D Sbjct: 314 PALMDAGVTGINLMTYDFFTLGDGKLSHHTNIYRDPSDV--YSKYSIDDAVTHLIDEKKV 371 Query: 257 SEKLI-VGFPAYGH-----TFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYE----- 305 K I +G+ Y T S PS+ + G YTD + L +E Sbjct: 372 DPKAIFIGYAGYTRNAKNATITTSIPSEEAL---------KGTYTDANQTLGSFEYSVLE 422 Query: 306 ----VCTFLN-------EGATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDN 352 +C +++ G V D + Y Y ++ D RS + K +++KD Sbjct: 423 WTDIICHYMDFEKGEGRNGYKLVHDKVAKADYLYSEATKVFISLDTPRSVRDKGRYVKDK 482 Query: 353 NLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLK 384 LGG +W D D+ G + H L +K Sbjct: 483 GLGGLFIWSGDQDN--GILTNAAHEGLKRRIK 512 >4W5U-B nrPDB Length = 408 Score = 74.7 bits (182), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 101/384 (26%), Positives = 148/384 (38%), Gaps = 74/384 (19%) Query: 25 MCYYTSWAK-DRPIEGSFKPGNID----PCLCTHLIYAFAGMQNNEITY----------- 68 + Y+T W DR +F N+D TH+ YAF + + Sbjct: 44 LGYFTEWGTYDR----NFNVKNLDTSGTAAKITHINYAFGNVTGGKCAIGDSYADYDKAF 99 Query: 69 -----------THEQDLR-DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNR 116 T +Q LR ++ L LK K +K L + GGW + F+ PQ Sbjct: 100 TADQSVSGQADTWDQPLRGNFNQLRQLKAKYPHIKVLWSFGGWTW-SGGFADAAKDPQG- 157 Query: 117 QIFIQSVIRFLRQYN----FDGLNLDWQYPGSRG--SPPKDKHLFSVLVKEMRKAFEEES 170 F QS + FDG+++DW+YP + G F L+ +R F +E Sbjct: 158 --FAQSCYNLVHDPRWDGVFDGIDIDWEYPNACGLTCDSSGPDAFRNLMAALRSTFGDEL 215 Query: 171 VEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKD--GYTGENSPL 228 V + T G I+ +Q +D+ VMTYD D G T +SPL Sbjct: 216 V---TAAVTADGTPGGKIEATD----YAGAAQYVDWYNVMTYDFFGAWDAQGPTAPHSPL 268 Query: 229 YKSPYD-IGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGI--GAPT 285 + YD I K + D+I ++ K G ++KL++G YG + TG+ AP Sbjct: 269 --TSYDGIPKQGFTSADAIAAF-KAQGVPADKLLLGIGFYGRGW-------TGVTQDAPG 318 Query: 286 ISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLK 345 + P T E G+ Y + + V YA+ G+ YD + K Sbjct: 319 GTATGPAAGTWEQGIEDYKVL-----KNTCPVTGTVAGTAYAHCGSNLWSYDTPDTIASK 373 Query: 346 AQWLKDNNLGGAVVWPLDMDDFSG 369 W D L GA W DFSG Sbjct: 374 MAWANDQGLRGAFAW-----DFSG 392 >4TXG-A nrPDB Length = 793 Score = 64.3 bits (155), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 75/353 (21%), Positives = 135/353 (38%), Gaps = 85/353 (24%) Query: 19 GSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQ------ 72 GS +++ Y+TSW + ++ +I TH+ YAFA + + +E Sbjct: 151 GSRRRIIGYFTSWRTGKDGSPAYLASDIPWSKLTHINYAFAHVDGSNKLSVNETAPGNPA 210 Query: 73 -DLR-----------------DYEALNGLKDKNTELKTLLAIGGW------------KFG 102 D+ + L K K +KTL+++GGW + Sbjct: 211 TDMSWPGVAGAEMDASLPYKGHFNLLTQYKRKYPGVKTLISVGGWAETGGYFDANGKRVA 270 Query: 103 PAPFSAMVSTPQNR------QIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSP--PKDKHL 154 F +M F S + FLR+Y FDG+++D++YP S + P D Sbjct: 271 SGGFYSMTVNADGTVNQAGINAFSDSAVAFLRKYGFDGVDIDFEYPTSMNNAGNPLDWTF 330 Query: 155 FSVLVKEMRKAFE----------EESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS--- 201 + + + K + + + +D +T+ V SGY + + Sbjct: 331 SNARLGSLNKGYVALLQTLRDRLDRAAAQDGRYYQITAA------VPASGYLLRGMETFQ 384 Query: 202 --QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADL------------NVDSII 247 + LD++ VM+YDLH + + G N+ L YD GK A+L N+ + Sbjct: 385 GLKYLDFVNVMSYDLHGAWNRFVGPNAAL----YDDGKDAELAFWNVYSTPQYGNIGYLN 440 Query: 248 SYWKDH----GAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTD 296 + W H G + ++ +G P Y + G+ ++ + P T+ Sbjct: 441 TDWAYHYYRGGLPASRVNMGVPYYTRGWKNVSGGSNGLWGSSVGSNCPAGLTE 493 >4Q6T-A nrPDB Length = 351 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 58/256 (22%), Positives = 101/256 (39%), Gaps = 38/256 (14%) Query: 120 IQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLL 179 ++ +++ ++ F G+NLD++ P+++ F VK + A + + L Sbjct: 102 VKQLVKLAKEGGFAGINLDFE-----KVEPRNRAAFCAFVKTLGNALHASN------KKL 150 Query: 180 LTSTGAGIIDV---IKSGYKIPELSQSLDYIQVMTYDLHDP---KDGYTGENSPLYKSPY 233 + S + D GY L ++DY QVMTYD P G+ E P +S + Sbjct: 151 IISIPPKLSDTEPEYLQGYDYKALGAAVDYFQVMTYDQVGPGWSSGGFHNEAWPGPESGF 210 Query: 234 DIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGK 293 D + +++SY AS K++ G P YG + + + I+ Sbjct: 211 DWQQ-------ALLSYAVSRVPAS-KVLAGLPTYGQDYSIGNRVHWSAYQEIIAEHRAAI 262 Query: 294 YTDESGLLAYYE---VCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLK 350 + D + Y V +F+ D + P Q W YD+ S K K + Sbjct: 263 HRDAASATPYATWGPVKSFV--------DGVEWTPERAQPVLW--YDDAASIKTKTALVT 312 Query: 351 DNNLGGAVVWPLDMDD 366 LGG VW + ++ Sbjct: 313 RLGLGGTSVWAMGYEN 328 >3CO4-A nrPDB Length = 312 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 45/193 (23%), Positives = 85/193 (44%), Gaps = 52/193 (26%) Query: 90 LKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPP 149 +K L+++ K P F+ ++ P+ R+ IQ +I F ++Y DG ++D++ Sbjct: 66 VKILISLA--KNSPGEFTTAINDPKARKELIQQIIAFTKEYKLDGFDIDYE--------- 114 Query: 150 KDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIID--------VIKSGYKI--PE 199 E ++ +K+ P LL+ + G + + S + E Sbjct: 115 -----------------EYDNWDKNFPSLLVFARGLYLAKEKNMLMTCAVNSRWLNYGTE 157 Query: 200 LSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASE- 258 Q DYI +M+YD + +T + P+ + YD D D + YW + AS+ Sbjct: 158 WEQYFDYINLMSYD----RGAFT--DKPVQHASYD-----DFVKD--LKYWNEQCRASKS 204 Query: 259 KLIVGFPAYGHTF 271 K++ G P YG+++ Sbjct: 205 KIVGGLPFYGYSW 217 >4WIW-A nrPDB Length = 349 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 43/192 (22%), Positives = 85/192 (44%), Gaps = 29/192 (15%) Query: 104 APFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRG--SPPKD--KHLFSVLV 159 A + ++ +P R+ I ++ L+ N DG+ +D++ P G P D ++ + + Sbjct: 85 ATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFM 144 Query: 160 KEMRKAFEEES---VEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHD 216 + + + + V +PR+ S+ +D Y LS ++DY+ VMTYD H Sbjct: 145 ESLHSELQSMNKLVVMAVMPRM---SSSQYWLD----AYDYEALSHAVDYLHVMTYDHHY 197 Query: 217 PKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDP 276 T P+ P+ + +++Y + G K+++G P YG +++ Sbjct: 198 R----TSAPGPIAPYPW---------IKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVD-- 242 Query: 277 SKTGIGAPTIST 288 K G PT ++ Sbjct: 243 GKDANGNPTYNS 254 >5JH8-A nrPDB Length = 317 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 63/278 (22%), Positives = 113/278 (40%), Gaps = 56/278 (20%) Query: 97 GGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFS 156 G W A + VST Q + ++++F + F G+N+D++ D++ FS Sbjct: 74 GNWS---ADIAHAVSTSAQSQA-VANLVKFAQDKRFSGINVDFE-----AVAQGDRNNFS 124 Query: 157 VLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDV---IKSGYKIPELSQSLDYIQVMTYD 213 ++ + +A + + +L+++ D GY + L + DY+Q+M+YD Sbjct: 125 HFIQVLGRALHAKGL-----KLIVSVPAFSAKDENHPANYGYDLRALGAAADYLQIMSYD 179 Query: 214 LHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFIL 273 P + P+ S + + D V+ + + K++ G PAYG+ Sbjct: 180 EAIP----AWDPGPVAGSDW-MEDDLDYAVERV---------PAAKILNGIPAYGY---- 221 Query: 274 SDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDA-PQEVPYAYQGNE 332 D + G G + D L+A Y GA +DA + + Y + Sbjct: 222 -DWKRPGDGGMLY-------WKDTQALIARY--------GAQPRYDAGTHSLTFNYGAAD 265 Query: 333 W----VGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 V +N RS LKA + LGG ++ L M+D Sbjct: 266 GSRHTVWTENARSVALKASLVNAYGLGGTSLYALGMED 303 >3CZ8-A nrPDB Length = 319 Score = 35.8 bits (81), Expect = 0.032, Method: Compositional matrix adjust. Identities = 57/298 (19%), Positives = 113/298 (37%), Gaps = 64/298 (21%) Query: 84 KDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPG 143 + + T L T+ + F +++ P R + ++ + + G+ +D++ Sbjct: 64 QRRVTPLATITNLTSGGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGYGGVTIDFEQVS 123 Query: 144 SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK--SGYKIPELS 201 + D+ LF+ ++++R + +L + A D I GY + Sbjct: 124 A-----ADRDLFTGFLRQLRDRLQAGGY------VLTIAVPAKTSDNIPWLRGYDYGGIG 172 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 ++Y+ +M YD H G +P+ +I ++ + + + S K+I Sbjct: 173 AVVNYMFIMAYDWHHAGSE-PGPVAPIT----EIRRTIEFTIAQV---------PSRKII 218 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTIST----------GPPGKYTDE--SGLLAYYEVCTF 309 +G P YG+ +I+ P + G A IS P +Y+ E S Y + Sbjct: 219 IGVPLYGYDWII--PYQPGTVASAISNQNAIERAMRYQAPIQYSAEYQSPFFRYSD---- 272 Query: 310 LNEGAT-EVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 +G T EVW ++ VRS K Q +++ L W L + + Sbjct: 273 -QQGRTHEVW-----------------FEGVRSMSRKMQIVREYRLQAIGAWQLTLAE 312 >3VPX-A nrPDB Length = 364 Score = 35.8 bits (81), Expect = 0.034, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 10/96 (10%) Query: 75 RDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFD- 133 +DYE L +DK + LK ++AI GPA + T + + I+ +R R + Sbjct: 10 QDYEQLVICQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEEAIEDALRLARGMTYKN 69 Query: 134 ---GLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAF 166 GLNL G+P DK+ EM +AF Sbjct: 70 AAAGLNLGGGKTVIIGNPKTDKN------DEMFRAF 99 >1LEH-A nrPDB Length = 364 Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust. Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 6/89 (6%) Query: 76 DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFD-- 133 DYE L +D+ + LK ++AI GPA A + T + I+ +R R + Sbjct: 11 DYEQLVFCQDEASGLKAVIAIHDTTLGPALGGARMWTYNAEEEAIEDALRLARGMTYKNA 70 Query: 134 --GLNLDWQYPGSRGSPPKDKH--LFSVL 158 GLNL G P DK+ +F L Sbjct: 71 AAGLNLGGGKTVIIGDPFADKNEDMFRAL 99 >2Y8V-A nrPDB Length = 290 Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust. Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 7/121 (5%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 +++CY+ + +R S P + TH+I A + + T D D+E N Sbjct: 14 RVICYHQTLCPNRGDYVSVLPLVKNNTGVTHIIIAAFHLNEDPGHITLNDDPPDHEMYNP 73 Query: 83 LKD-----KNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNL 137 L K + +K + +GG G + + + + + Q ++ +R++ DGL+L Sbjct: 74 LWAEVPVLKRSGVKVMGMLGGAAQGS--YRCLDGDQEKFERYYQPLLAMVRRHQLDGLDL 131 Query: 138 D 138 D Sbjct: 132 D 132 >3K4O-A nrPDB Length = 266 Score = 30.8 bits (68), Expect = 0.95, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%) Query: 79 ALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQ------SVIRFLRQYNF 132 AL+ K++N E+K +L GG FG + ++IFI + R +R++N Sbjct: 42 ALDYYKNQNKEIKLILVHGGGAFGHPVAKKYLKIEDGKKIFINMEKGFWEIQRAMRRFN- 100 Query: 133 DGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK 192 N+ S P S +V + F+ ++++ + R L+ I+ K Sbjct: 101 ---NIIIDTLQSYDIPAVSIQPSSFVVFGDKLIFDTSAIKEMLKRNLVPVIHGDIVIDDK 157 Query: 193 SGYKI 197 +GY+I Sbjct: 158 NGYRI 162 >4RL3-A nrPDB Length = 272 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/105 (20%), Positives = 48/105 (45%), Gaps = 10/105 (9%) Query: 46 IDPCLCTHLIYAFA-------GMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 98 I+ + H I AFA N + + A+ +K +++ +K ++++GG Sbjct: 22 INSGVTFHFILAFAIDYTSAAAATNGVFNIYWQNSVLTPAAVQAIKAQHSNVKVMVSLGG 81 Query: 99 WKFGPAP--FSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 +P F+A S + S+ + QY+ DG+++D+++ Sbjct: 82 DTISGSPVQFTA-TSVSSWVANAVSSLTSLINQYHLDGIDIDYEH 125 >4TX8-A nrPDB Length = 439 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 13/67 (19%) Query: 72 QDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYN 131 QD+R +A K K K +L++GG S ++ Q F+ S+ L QY Sbjct: 165 QDIRAQQA----KGK----KVVLSLGGQNG-----SVTLNNATQVQNFVNSLYGILTQYG 211 Query: 132 FDGLNLD 138 FDG++LD Sbjct: 212 FDGIDLD 218 >3EBV-A nrPDB Length = 302 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 5/50 (10%) Query: 91 KTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQ 140 K ++++GG K + V++ + F SV +R+Y FDG+++D + Sbjct: 77 KVIISVGGEKG-----TVSVNSSASATNFANSVYSVMREYGFDGVDIDLE 121 >4LRU-A nrPDB Length = 239 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 42/154 (27%), Positives = 63/154 (40%), Gaps = 22/154 (14%) Query: 254 GAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG 313 G+ K+++ +Y TF SD KTG+ + P + + G YE+ +E Sbjct: 1 GSHMVKVLLALTSYNETF-YSDGKKTGVFV--VEALHPFEVFRKKG----YEI-QLASET 52 Query: 314 ATEVWDAPQEVPYAYQGNEWVGYDNVRS-FKLKAQWLKDNNLGGAVVWPLDMDDFSGSFC 372 T WD VP G + +DNV S F + + LK + + P D D F GS Sbjct: 53 GTFGWDDHSVVPDFLNGEDKEIFDNVNSEFNVALKNLKK----ASDLDPNDYDIFFGSAG 108 Query: 373 HQRHF---------PLTSTLKGDLNIHSASCKGP 397 H F + +T+ + SA C GP Sbjct: 109 HGTLFDYPNAKDLQKIATTVYDKGGVVSAVCHGP 142 >5AN9-C nrPDB Length = 205 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 10/82 (12%) Query: 241 LNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPT---ISTGPPGKYTDE 297 L ++ I + KD+ A +++I +T + P+K G+ AP I GP G + Sbjct: 81 LKQNTCIIFCKDNIAEVKRVI-------NTQRVGAPAKAGVFAPNDVIIPAGPTGMEPTQ 133 Query: 298 SGLLAYYEVCTFLNEGATEVWD 319 + L ++ T +N G ++ + Sbjct: 134 TSFLQDLKIATKINRGQIDIVN 155 >6MJ1-A nrPDB Length = 207 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 231 SPYDIGKSADLNVDSIISYWKDHGAASEKLIVGF 264 S +I KSAD+NV I Y+K G E L+ F Sbjct: 26 SVREIAKSADVNVAHISYYFKGKGGLMEHLVSEF 59 >6ACF-A nrPDB Length = 367 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Query: 76 DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFD-- 133 DYE + +DK + LK ++ I GPA + + + ++ +R R + Sbjct: 11 DYEQVLFCQDKESGLKAIIVIHDTTLGPALGGTRMWMYNSEEEALEDALRLARGMTYKNA 70 Query: 134 --GLNLDWQYPGSRGSPPKDKH 153 GLNL G P KDK+ Sbjct: 71 AAGLNLGGGKTVIIGDPRKDKN 92 >1PYS-B nrPDB Length = 785 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 26/113 (23%), Positives = 46/113 (40%), Gaps = 12/113 (10%) Query: 111 STPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPK---DKHLFSVLVKEMRKAFE 167 S P+ QI I + G ++ + P R +PP D L LV+E+ + Sbjct: 418 SYPEAEQIAILKRL---------GCRVEGEGPTYRVTPPSHRLDLRLEEDLVEEVARIQG 468 Query: 168 EESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDG 220 E++ +P G+ + ++ E+ L + +V TY DP+D Sbjct: 469 YETIPLALPAFFPAPDNRGVEAPYRKEQRLREVLSGLGFQEVYTYSFMDPEDA 521 >3BF5-A nrPDB Length = 306 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 6/42 (14%) Query: 286 ISTGPPGKYTDESGLLAYYEV-----CTFLNEGATEVWDAPQ 322 I+TG K+ DESG + Y +F+++GA W APQ Sbjct: 96 INTGHVEKFEDESGPICYIATDGKKQVSFMHQGAMAAW-APQ 136 >3SIM-A nrPDB Length = 275 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 14/71 (19%), Positives = 37/71 (52%), Gaps = 13/71 (18%) Query: 78 EALNGLKDKNTELKTLLAIGGW-------KFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY 130 + ++ +K + ++ +++GG +F A + VS + S+ R +++Y Sbjct: 64 DQISAIKSSHPNVRVAVSLGGASVGSNTVQFQAASVDSWVSNA------VTSLTRIIQRY 117 Query: 131 NFDGLNLDWQY 141 N DG+++D+++ Sbjct: 118 NLDGIDIDYEH 128 >3ZVX-A nrPDB Length = 261 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 21/94 (22%) Query: 265 PAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEV 324 PA G F ++ P T I +G G GLL + T LNE A +V + Sbjct: 93 PADGIAFFIAPPDTT------IPSGSAG------GLLGLFNPRTALNESANQVLAVEFDT 140 Query: 325 PYAYQGNEW------VGYD--NVRSFKLKAQWLK 350 +A N W +G D ++RS K+ +W + Sbjct: 141 FFAQNSNTWDPNYQHIGIDVNSIRSSKV-VRWER 173 >3GX8-A nrPDB Length = 121 Score = 27.7 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 143 GSRGSPPKDKHLFSVLVK-EMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 G++G P ++VL E+R+ +E S IP+L + G DVI S + EL+ Sbjct: 42 GNQGVDPAKFAAYNVLEDPELREGIKEFSEWPTIPQLYVNKEFIGGCDVITSMARSGELA 101 Query: 202 QSLDYIQVM 210 L+ Q + Sbjct: 102 DLLEEAQAL 110 >3N18-A nrPDB Length = 333 Score = 27.7 bits (60), Expect = 9.5, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 9/55 (16%) Query: 86 KNTELKTLLAIGGWKFGPAPFSAMVSTPQN--RQIFIQSVIRFLRQYNFDGLNLD 138 K+ K +L+IGG + +V P N + FI S+ + +Y FDG+++D Sbjct: 69 KSKGKKVVLSIGGQ-------NGVVLLPDNAAKDRFINSIQSLIDKYGFDGIDID 116 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1E9L-A nrPDB 547 e-156 3RM8-A nrPDB 536 e-153 1WB0-A nrPDB 512 e-145 4WKA-A nrPDB 506 e-144 5XEP-A nrPDB 492 e-139 5WUS-A nrPDB 484 e-137 5WV8-A nrPDB 481 e-136 1HJW-A nrPDB 479 e-136 4P8U-A nrPDB 459 e-130 2QF8-A nrPDB 455 e-128 6G9C-A nrPDB 438 e-123 3W4R-A nrPDB 436 e-123 3WKZ-A nrPDB 424 e-119 5Y29-A nrPDB 421 e-118 5Y2C-A nrPDB 411 e-115 1ITX-A nrPDB 350 5e-97 6BT9-A nrPDB 349 1e-96 5GZU-A nrPDB 329 1e-90 3AQU-A nrPDB 328 3e-90 5GQB-A nrPDB 327 5e-90 6EPB-A nrPDB 324 5e-89 3G6L-A nrPDB 320 5e-88 3CHF-A nrPDB 320 6e-88 3ALF-A nrPDB 319 1e-87 4MNK-A nrPDB 316 1e-86 5ZL9-A nrPDB 308 4e-84 1LL6-A nrPDB 304 4e-83 5Z7M-A nrPDB 301 3e-82 5DF0-A nrPDB 297 6e-81 4URI-A nrPDB 289 1e-78 3ARQ-A nrPDB 288 2e-78 3WD0-A nrPDB 285 3e-77 6F8N-A nrPDB 281 3e-76 1KFW-A nrPDB 281 3e-76 1JNE-A nrPDB 281 4e-76 3QOK-A nrPDB 276 2e-74 4W5U-B nrPDB 263 8e-71 4TXG-A nrPDB 258 4e-69 5XWF-A nrPDB 250 9e-67 4A5Q-A nrPDB 232 3e-61 4DWS-C nrPDB 229 2e-60 6OGD-C nrPDB 227 6e-60 4Q6T-A nrPDB 155 2e-38 4WIW-A nrPDB 144 6e-35 3CO4-A nrPDB 140 1e-33 5JH8-A nrPDB 130 1e-30 Sequences not found previously or not previously below threshold: 3CZ8-A nrPDB 106 2e-23 4S3K-A nrPDB 94 7e-20 4S3J-A nrPDB 94 1e-19 3BXW-B nrPDB 70 2e-12 3IAN-A nrPDB 61 1e-09 4RL3-A nrPDB 58 6e-09 3SIM-A nrPDB 58 6e-09 3EBV-A nrPDB 56 2e-08 4TX8-A nrPDB 56 3e-08 1NAR-A nrPDB 52 5e-07 4W5Z-A nrPDB 52 6e-07 2Y8V-A nrPDB 50 2e-06 4MB4-A nrPDB 50 2e-06 3N18-A nrPDB 48 7e-06 4AXN-A nrPDB 47 1e-05 1EDT-A nrPDB 44 1e-04 2EBN-A nrPDB 43 3e-04 4GUW-A nrPDB 40 0.002 1F8Q-A nrPDB 38 0.005 6MDV-A nrPDB 38 0.007 4NUY-A nrPDB 34 0.13 4TOQ-A nrPDB 33 0.31 6Q64-A nrPDB 32 0.35 2XVP-A nrPDB 32 0.52 4AEF-A nrPDB 32 0.54 2GSJ-A nrPDB 31 1.1 3Q6J-A nrPDB 30 1.3 4KVF-A nrPDB 30 1.3 4WM7-C nrPDB 30 1.9 1R8K-A nrPDB 30 1.9 1PTM-A nrPDB 30 1.9 3V6B-R nrPDB 30 2.4 3V2A-R nrPDB 30 2.4 3S35-X nrPDB 30 2.4 2X1X-R nrPDB 30 2.4 2PZM-A nrPDB 30 2.5 3U0W-H nrPDB 30 2.6 3MU7-A nrPDB 29 2.9 2NYA-A nrPDB 29 3.7 6FTI-5 nrPDB 28 6.1 3NJT-A nrPDB 28 6.7 3D5H-A nrPDB 28 6.7 2WOQ-A nrPDB 28 6.7 1V5D-A nrPDB 28 9.0 >1E9L-A nrPDB Length = 377 Score = 547 bits (1410), Expect = e-156, Method: Composition-based stats. Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN Sbjct: 1 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY Sbjct: 61 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS Sbjct: 121 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 180 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI Sbjct: 181 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 240 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP Sbjct: 241 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 300 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS Sbjct: 301 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 360 Query: 382 TLKGDLNIHSASCKGPY 398 TLKGDLNIHSASCKGPY Sbjct: 361 TLKGDLNIHSASCKGPY 377 >3RM8-A nrPDB Length = 395 Score = 536 bits (1382), Expect = e-153, Method: Composition-based stats. Identities = 256/376 (68%), Positives = 305/376 (81%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 YQL CY+T+WA+ RP G F P +I+PCLCTHLIYAFAGMQNNEIT D+ Y+A N Sbjct: 1 YQLTCYFTNWAQYRPGLGRFMPDDINPCLCTHLIYAFAGMQNNEITTIEWNDVTLYQAFN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 GLK+KN++LKTLLAIGGW FG APF+AMVSTP+NRQ FI SVI+FLRQY FDGL+ DW+Y Sbjct: 61 GLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEY 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PGSRGSPP+DKHLF+VLV+EMR+AFE+E+ + + PRL++T+ A I I+SGY+IP+LS Sbjct: 121 PGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLS 180 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 Q LDYI VMTYDLH +GYTGENSPLYK P D G +A LNVD +++YWKD+GA +EKLI Sbjct: 181 QYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLI 240 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 VGFP YGH FILS+PS TGIGAPT GP G Y ESG+ AYYE+CTFL GAT+ WDAP Sbjct: 241 VGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAP 300 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 QEVPYAYQGN WVGYDNV+SF +KAQWLK N GGA+VW +D+DDF+G+FC+Q FPL S Sbjct: 301 QEVPYAYQGNVWVGYDNVKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLIS 360 Query: 382 TLKGDLNIHSASCKGP 397 TLK L + SASC P Sbjct: 361 TLKKALGLQSASCTAP 376 >1WB0-A nrPDB Length = 445 Score = 512 bits (1318), Expect = e-145, Method: Composition-based stats. Identities = 176/367 (47%), Positives = 250/367 (68%), Gaps = 2/367 (0%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 +L+CY+T+WA+ R E F P ++DP LCTHLIYAFAGM N++++ T D Y+ NG Sbjct: 2 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 61 Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 142 LK N +LKTLLAIGGW FG F+ MV+T NRQ F+ S IRFLR+Y+FDGL+LDW+YP Sbjct: 62 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 121 Query: 143 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 GS+GSP DK F+ LV+++ AF++E+ RLLL++ + +GY++ +++Q Sbjct: 122 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 181 Query: 203 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 262 +LD++ +M YD H + TG NSPLYK + G +A LNVD+ + W G + KLI+ Sbjct: 182 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 241 Query: 263 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQ 322 G P YG +F L+ S T +GAP +G PG +T E G+LAYYEVC++ +GAT+ Q Sbjct: 242 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQ 299 Query: 323 EVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTST 382 +VPY ++ N+WVG+D+V SFK K +LK LGGA+VW LD+DDF+G C+Q +PL T Sbjct: 300 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQT 359 Query: 383 LKGDLNI 389 L+ +L++ Sbjct: 360 LRQELSL 366 >4WKA-A nrPDB Length = 377 Score = 506 bits (1302), Expect = e-144, Method: Composition-based stats. Identities = 176/367 (47%), Positives = 250/367 (68%), Gaps = 2/367 (0%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 +L+CY+T+WA+ R E F P ++DP LCTHLIYAFAGM N++++ T D Y+ NG Sbjct: 2 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 61 Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 142 LK N +LKTLLAIGGW FG F+ MV+T NRQ F+ S IRFLR+Y+FDGL+LDW+YP Sbjct: 62 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 121 Query: 143 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 GS+GSP DK F+ LV+++ AF++E+ RLLL++ + +GY++ +++Q Sbjct: 122 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 181 Query: 203 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 262 +LD++ +M YD H + TG NSPLYK + G +A LNVD+ + W G + KLI+ Sbjct: 182 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 241 Query: 263 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQ 322 G P YG +F L+ S T +GAP +G PG +T E G+LAYYEVC++ +GAT+ Q Sbjct: 242 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQ 299 Query: 323 EVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTST 382 +VPY ++ N+WVG+D+V SFK K +LK LGGA+VW LD+DDF+G C+Q +PL T Sbjct: 300 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQT 359 Query: 383 LKGDLNI 389 L+ +L++ Sbjct: 360 LRQELSL 366 >5XEP-A nrPDB Length = 381 Score = 492 bits (1266), Expect = e-139, Method: Composition-based stats. Identities = 163/389 (41%), Positives = 239/389 (61%), Gaps = 9/389 (2%) Query: 1 MAKLILVTGLAILLNVQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAG 60 M +TG A+L+ +Q S+Y+L+CY+TSW++ R GSF P I P LCTH+IY+FA Sbjct: 1 MGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFAN 60 Query: 61 MQNNE-ITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIF 119 + ++ ++ D +Y+ LN LK +NT LKTLL++GGWKFG FS + S + R F Sbjct: 61 ISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGGKRFSEIASNTERRTAF 120 Query: 120 IQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLL 179 ++SV FLR Y FDGL+L W YP R DK FS L+KE+ F +E V+ +LL Sbjct: 121 VRSVAPFLRSYGFDGLDLAWLYPRLR-----DKQYFSTLIKELNAEFTKE-VQPGREKLL 174 Query: 180 LTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSA 239 L++ + I +GY I +++Q LD+I +MTYD H TG +SPL++ D Sbjct: 175 LSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDR 234 Query: 240 DLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESG 299 NV+ + Y GA + KL++G P +G +F L+ S+ +GAP G PG++T E+G Sbjct: 235 YSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLAS-SENQLGAPISGEGLPGRFTKEAG 293 Query: 300 LLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVV 359 LAYYE+C FL +GA + ++VP+A +GN+WVGY++ S K K ++LK+ L GA+V Sbjct: 294 TLAYYEICDFL-KGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVRFLKEKKLAGAMV 352 Query: 360 WPLDMDDFSGSFCHQRHFPLTSTLKGDLN 388 W LD+DDF G+ + FPLT+ +K L Sbjct: 353 WALDLDDFQGTCQPKEFFPLTNAIKDALA 381 >5WUS-A nrPDB Length = 460 Score = 484 bits (1247), Expect = e-137, Method: Composition-based stats. Identities = 163/379 (43%), Positives = 227/379 (59%), Gaps = 8/379 (2%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 82 Q++CY TSW+ RP G F P N+DP LCTH+IYAFA ++++++T E+D Y+ + Sbjct: 3 QVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVA 62 Query: 83 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 142 L++KN LK LLAIGGW FG PF + S F+ I FLR Y F+GL++DW+YP Sbjct: 63 LREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYP 122 Query: 143 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 D+ F L+KE+R AFE E+ PRLLLT+ + I +GY +PE+S+ Sbjct: 123 RG----ADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISK 178 Query: 203 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 262 LD+I VMTYD H + G NSPL+ L VD W GA EKL++ Sbjct: 179 YLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMI 238 Query: 263 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNE-GATEVWDAP 321 G P YG +F L + ++ IGAP G G++T+E+G ++YYE+C FL E T VWD Sbjct: 239 GMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNE 298 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 Q VP+AY+ ++WVG+D+ RS K K WLK+ GG +VW +DMDDF GS C +PL + Sbjct: 299 QMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGS-CGTGKYPLIT 357 Query: 382 TLKGDLNIHSASCK--GPY 398 +K +L+ + + GPY Sbjct: 358 AMKQELSGYKVKLEYDGPY 376 >5WV8-A nrPDB Length = 482 Score = 481 bits (1237), Expect = e-136, Method: Composition-based stats. Identities = 166/379 (43%), Positives = 224/379 (59%), Gaps = 11/379 (2%) Query: 20 SSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLR---- 75 Y+++CYYT+W++ R G F P +I P LCTH+I+AF ++ +++ D Sbjct: 91 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGK 150 Query: 76 --DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFD 133 Y+ +N LK N +LKTLLAIGGW FG F M +T RQ FI S I +LR NFD Sbjct: 151 TGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFD 210 Query: 134 GLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKS 193 GL++DW YP DK + +L+KE+R+AFE E+ E PRLLLT+ D IKS Sbjct: 211 GLDIDWLYPKGG----DDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKS 266 Query: 194 GYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDH 253 GY +P ++ LD+I +M YD H + TG N+PLY D L+VD W Sbjct: 267 GYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKL 326 Query: 254 GAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG 313 GA EKLI+G P YG TF LS+P+ + +P G G+YT ESG LAYYEVC L G Sbjct: 327 GAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNG 386 Query: 314 ATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCH 373 VWD +VPYA G++WVG+D+ +S + K +W+KDN+ GGA+VW +DMDDFSG C Sbjct: 387 GAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCG 446 Query: 374 QR-HFPLTSTLKGDLNIHS 391 +PL ++ +L S Sbjct: 447 GNVKYPLIGAMREELRGIS 465 >1HJW-A nrPDB Length = 362 Score = 479 bits (1233), Expect = e-136, Method: Composition-based stats. Identities = 170/368 (46%), Positives = 230/368 (62%), Gaps = 9/368 (2%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 Y+L+CYYTSW++ R +GS P +D LCTH+IY+FA + N+ I D+ Y LN Sbjct: 1 YKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 LK++N LKTLL++GGW FG FS + S Q+R+ FI+SV FLR + FDGL+L W Y Sbjct: 61 TLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLY 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PG R DK F+ L+KEM+ F +E+ + +LLL++ + I S Y I ++S Sbjct: 121 PGRR-----DKQHFTTLIKEMKAEFIKEA-QPGKKQLLLSAALSAGKVTIDSSYDIAKIS 174 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 Q LD+I +MTYD H G TG +SPL++ D N D + Y GA + KL+ Sbjct: 175 QHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLV 234 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 +G P +G +F L+ S+TG+GAP G PG++T E+G LAYYE+C FL GAT Sbjct: 235 MGIPTFGRSFTLAS-SETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLR-GATVHRILG 292 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQR-HFPLT 380 Q+VPYA +GN+WVGYD+ S K K Q+LKD L GA+VW LD+DDF GSFC Q FPLT Sbjct: 293 QQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLT 352 Query: 381 STLKGDLN 388 + +K L Sbjct: 353 NAIKDALA 360 >4P8U-A nrPDB Length = 371 Score = 459 bits (1182), Expect = e-130, Method: Composition-based stats. Identities = 161/370 (43%), Positives = 239/370 (64%), Gaps = 9/370 (2%) Query: 21 SYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEAL 80 SY+L+CY+T+W++DR G F P NIDP LC+HLIY+FA ++NN++ + ++ Y+ + Sbjct: 7 SYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTI 66 Query: 81 NGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQ 140 N LK KN +LK LL+IGG+ FG F MV + +R FI S+I FLR +NFDGL++ W Sbjct: 67 NSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWI 126 Query: 141 YPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPEL 200 YP K+ F+VL+ E+ +AF+++ + RLLLT + +I + Y++ +L Sbjct: 127 YP-----DQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVEKL 181 Query: 201 SQSLDYIQVMTYDLHDPKDG--YTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASE 258 ++ LD+I ++++D H + TG NSPL K D G S+ NV+ + YW G SE Sbjct: 182 AKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSE 241 Query: 259 KLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVW 318 K+++G P YGH+F L+ ++T +GAP G G T+ SG LAYYE+C FL +GA W Sbjct: 242 KVVMGIPTYGHSFTLAS-AETTVGAPASGPGAAGPITESSGFLAYYEICQFL-KGAKITW 299 Query: 319 DAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFP 378 Q+VPYA +GN+WVGYD+V+S + K Q+LK+ NLGGA++W +DMDDF+G C+Q +P Sbjct: 300 LQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYP 359 Query: 379 LTSTLKGDLN 388 L +K L Sbjct: 360 LVQAVKRSLG 369 >2QF8-A nrPDB Length = 361 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 166/368 (45%), Positives = 229/368 (62%), Gaps = 10/368 (2%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 Y+L+CYYTSW++ R +GS P IDP LCTH+IY+FA + NNEI D+ Y+ LN Sbjct: 1 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLN 60 Query: 82 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 141 LK++N LKTLL++GGW +G FS + S Q+R+ FI+SV FLR + FDGL+L W + Sbjct: 61 TLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLW 120 Query: 142 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 PG R DK + LVKEM+ F E+ + +LLL++ I GY I ++S Sbjct: 121 PGWR-----DKRHLTTLVKEMKAEFVREA-QAGTEQLLLSAAVTAGKIAIDRGYDIAQIS 174 Query: 202 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 + LD+I ++TYD H G +SPL++ D S N D +SY GA + KL+ Sbjct: 175 RHLDFISLLTYDFHGAWRQTVGHHSPLFRGNED-ASSRFSNADYAVSYMLRLGAPANKLV 233 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 321 +G P +G ++ L+ SKT +GAP G PG++T G+LAYYE+C FL+ GAT Sbjct: 234 MGIPTFGRSYTLAS-SKTDVGAPISGPGIPGRFTKWKGILAYYEICDFLH-GATTHRFRD 291 Query: 322 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQR-HFPLT 380 Q+VPYA +GN+WV YD+ S K KA++LK+ L GA+VW LD+DDF G+FC Q FPLT Sbjct: 292 QQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLT 351 Query: 381 STLKGDLN 388 S +K L Sbjct: 352 SAIKDVLA 359 >6G9C-A nrPDB Length = 495 Score = 438 bits (1127), Expect = e-123, Method: Composition-based stats. Identities = 145/369 (39%), Positives = 205/369 (55%), Gaps = 10/369 (2%) Query: 26 CYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRD--YEALNGL 83 CY+T+WA+ RP G + P + LC ++ YAFA + ++ E + D Y + Sbjct: 37 CYFTNWAQYRPGNGKYNPEHYQANLCEYIFYAFAKLNDDFTVDQFEWNDIDVLYPGVMKQ 96 Query: 84 KDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPG 143 K +LK LL++GGW G A F M +T NR FI S++ FL+Q FDG +LDW+YP Sbjct: 97 KSSQPDLKVLLSLGGWNAGTATFKKMAATYSNRAKFISSLVSFLQQNKFDGFDLDWEYPE 156 Query: 144 SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQS 203 S DK + +L +E+ FEE + RLL T+ + + +GY +P L++ Sbjct: 157 S-----SDKENYLLLCQEILAKFEEVAKCTSTSRLLFTAAVSANPKTVDAGYDVPALAKV 211 Query: 204 LDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVG 263 LD++ +M YD H + TG NSPLY D + NV+ YW D G +++I+G Sbjct: 212 LDFVNLMCYDFHGAWETQTGINSPLYSRKEDSSEFKMWNVEQSSKYWSDKGMPKKQIIIG 271 Query: 264 FPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQE 323 P YG + LSD SKT IGAP + +Y E+G+++YYEVC L+ GA VWD + Sbjct: 272 LPTYGRGWTLSDASKTDIGAPAQGSSTATEYLREAGVISYYEVCQKLSSGAKRVWDDESK 331 Query: 324 VPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFC---HQRHFPLT 380 PY QGN+W YD+V S K K W+K N GGA VW LD DDF GSFC + + +PL Sbjct: 332 TPYLVQGNQWFSYDDVESMKAKINWIKQENYGGAFVWTLDYDDFLGSFCTEHNGKKYPLI 391 Query: 381 STLKGDLNI 389 S ++ L Sbjct: 392 SLMQEILGG 400 >3W4R-A nrPDB Length = 554 Score = 436 bits (1122), Expect = e-123, Method: Composition-based stats. Identities = 140/391 (35%), Positives = 213/391 (54%), Gaps = 21/391 (5%) Query: 16 VQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNE-----ITYTH 70 + S +++CY+++WA RP G + +I +CTH+IY+F G+ + I Sbjct: 19 AESDSRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPEL 78 Query: 71 EQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY 130 + D ++ L+ K+ +K +A+GGW G + +S MV+ R F++SV+ FL +Y Sbjct: 79 DVDKNGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKY 138 Query: 131 NFDGLNLDWQYPG--SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 NFDGL+LDW+YPG RG DK F LV+E+R+AF E + LT+ Sbjct: 139 NFDGLDLDWEYPGAADRGGSFSDKDKFLYLVQELRRAFIREGKGWE-----LTAAVPLAN 193 Query: 189 DVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIIS 248 + GY +PEL Q LD I VM+YDL G+ +SPLYK P+D LNV+ + Sbjct: 194 FRLMEGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQ 253 Query: 249 YWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTI----STGPPGKYTDESGLLAYY 304 W+D G + KL+VG P YG +F LS + I G P YT+ +G AYY Sbjct: 254 LWEDKGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYY 313 Query: 305 EVCTFLNEG---ATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWP 361 E+CT ++ T+ WD + PYAY+G +WVGY++ RS ++K W+K+ GA+ W Sbjct: 314 EICTEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWA 373 Query: 362 LDMDDFSGSFCHQRHFPLTSTLKGDLNIHSA 392 +DMDDF G C +++ L L ++ ++ Sbjct: 374 IDMDDFQG-LCGEKNI-LIKLLHKHMSAYTV 402 >3WKZ-A nrPDB Length = 395 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 141/391 (36%), Positives = 213/391 (54%), Gaps = 21/391 (5%) Query: 16 VQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNE-----ITYTH 70 + S +++CY+++WA RP G + +I +CTH+IY+F G+ + I Sbjct: 1 AESDSRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPEL 60 Query: 71 EQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY 130 + D ++ L+ K+ +K +A+GGW G + +S MV+ R F++SV+ FL +Y Sbjct: 61 DVDKNGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKY 120 Query: 131 NFDGLNLDWQYPG--SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 NFDGL+LDWQYPG RG DK F LV+E+R+AF E + LT+ Sbjct: 121 NFDGLDLDWQYPGAADRGGSFSDKDKFLYLVQELRRAFIREGKGWE-----LTAAVPLAN 175 Query: 189 DVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIIS 248 + GY +PEL Q LD I VM+YDL G+ +SPLYK P+D LNV+ + Sbjct: 176 FRLMEGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQ 235 Query: 249 YWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTI----STGPPGKYTDESGLLAYY 304 W+D G + KL+VG P YG +F LS + I G P YT+ +G AYY Sbjct: 236 LWEDKGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYY 295 Query: 305 EVCTFLNEG---ATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWP 361 E+CT ++ T+ WD + PYAY+G +WVGY++ RS ++K W+K+ GA+ W Sbjct: 296 EICTEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWA 355 Query: 362 LDMDDFSGSFCHQRHFPLTSTLKGDLNIHSA 392 +DMDDF G C +++ L L ++ ++ Sbjct: 356 IDMDDFQG-LCGEKNI-LIKLLHKHMSAYTV 384 >5Y29-A nrPDB Length = 377 Score = 421 bits (1082), Expect = e-118, Method: Composition-based stats. Identities = 145/382 (37%), Positives = 208/382 (54%), Gaps = 24/382 (6%) Query: 18 LGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEI----TYTHEQD 73 L S Y+L+CYYT+W+ RP G + P +IDP LCTH++Y FA + N+ + + D Sbjct: 3 LNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYD 62 Query: 74 LRDYEALNGLKDKNTELKTLLAIGGWKFGPA-PFSAMVSTPQNRQIFIQSVIRFLRQYNF 132 R YE + K +K LA+GGW +S +V+ P R F+Q + FL +Y F Sbjct: 63 NRFYERVVEYKR--YGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGF 120 Query: 133 DGLNLDWQYPGS-----RGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGI 187 DGL+LDW+YP P DK F+ LV E+ + + LLL++ + Sbjct: 121 DGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKG-------LLLSAAVSPN 173 Query: 188 IDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSII 247 VI +GY +P L++ LD+I VMTYD H D TG +PLY P D + N + I Sbjct: 174 KMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDD--DTTYFNANYTI 231 Query: 248 SYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVC 307 YW + G + K+++G P YG +F + + G+ P G PG+YT G LAYYE+C Sbjct: 232 HYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEIC 291 Query: 308 TFL-NEGATEVWDAPQ-EVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 + N G T V D Q PYAY+GN+WV +D+V K K ++K NLGG ++W LD+D Sbjct: 292 DRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLD 351 Query: 366 DFSGSFCHQRHFPLTSTLKGDL 387 D+ C Q PL + +K +L Sbjct: 352 DYRNR-CGQGKHPLLNAIKTEL 372 >5Y2C-A nrPDB Length = 383 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 138/385 (35%), Positives = 208/385 (54%), Gaps = 24/385 (6%) Query: 21 SYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITY-----THEQDLR 75 ++++CYYT+WA RP G + PG+I+P LCTH+IYAFA + E+ + + + Sbjct: 2 RFKVVCYYTNWAWYRPDNGKYTPGDINPELCTHIIYAFAVLDKEELVIKSHDIWLDVENK 61 Query: 76 DYEALNGLKDKNTELKTLLAIGGWKFGPA-PFSAMVSTPQNRQIFIQSVIRFLRQYNFDG 134 YE + LK +K LL +GGW +S +V+ R+ F+ + FL QY FDG Sbjct: 62 FYEKVTALKSH--GVKVLLGLGGWDDSAGDKYSRLVNNVSARRKFVVHAVDFLEQYGFDG 119 Query: 135 LNLDWQYP-----GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIID 189 L+LDW YP P DK F+ LVKE+RKAF +LL++ + Sbjct: 120 LDLDWLYPKCWQVECEKGPDSDKQGFADLVKELRKAFNRRG-------MLLSAAVSASKR 172 Query: 190 VIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISY 249 VI Y +P LS +LD+I +MTYD H D TG +P+Y D + NV+ ++Y Sbjct: 173 VIDYAYNVPALSMNLDWISLMTYDYHGQWDKKTGHVAPMYVHDKDTDNT--FNVNFTVNY 230 Query: 250 WKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTF 309 W + GA +KL+VG P YG +F + + + TG+GAPT + G G T G L++YE+C Sbjct: 231 WINKGADRKKLVVGVPFYGQSFSVVEGAGTGLGAPTYAGGEAGDETRARGFLSFYEICER 290 Query: 310 LNEGATEVWDAPQE--VPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDF 367 + +V P PYA ++WV +D+ + KA++++ LGG++ W LD+DDF Sbjct: 291 VKVKGWKVHRDPGGRIGPYATHDDQWVSFDDDFMARHKAEYVRAMELGGSMAWSLDLDDF 350 Query: 368 SGSFCHQRHFPLTSTLKGDLNIHSA 392 +G +C PL +T+ L A Sbjct: 351 TGKYCGCGKAPLLTTINHVLRGKEA 375 >1ITX-A nrPDB Length = 419 Score = 350 bits (899), Expect = 5e-97, Method: Composition-based stats. Identities = 113/431 (26%), Positives = 186/431 (43%), Gaps = 76/431 (17%) Query: 16 VQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEI--------- 66 + SY+++ YY SWA ++ +IDP TH+ YAFA + N I Sbjct: 6 AEAADSYKIVGYYPSWAAY---GRNYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGP 62 Query: 67 -------------------------------------TYTHEQDLRDYEALNGLKDKNTE 89 + + LN LK N Sbjct: 63 NPVTWTCQNEKSQTINVPNGTIVLGDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPN 122 Query: 90 LKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRG--- 146 LKT++++GGW + FS + +T R++F S + FLR+YNFDG++LDW+YP S G Sbjct: 123 LKTIISVGGWTWSNR-FSDVAATAATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDG 181 Query: 147 --SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSL 204 P+DK +++L+ ++R+ + LL ++GA + ++ +++ + Sbjct: 182 NSKRPEDKQNYTLLLSKIREKLDAAGAVDGKKYLLTIASGASA--TYAANTELAKIAAIV 239 Query: 205 DYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGK----SADLNVDSIISYWKDHGAASEKL 260 D+I +MTYD + + N+PL P + NV + D G + KL Sbjct: 240 DWINIMTYDFNGAWQKISAHNAPLNYDPAASAAGVPDANTFNVAAGAQGHLDAGVPAAKL 299 Query: 261 IVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEV-CTFLN-EGATEVW 318 ++G P YG + ++ G G TG T E+G +Y++ ++N G T W Sbjct: 300 VLGVPFYGRGWDGC--AQAGNGQYQTCTGGSSVGTWEAGSFDFYDLEANYINKNGYTRYW 357 Query: 319 DAPQEVPYAYQGNE--WVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRH 376 + +VPY Y + ++ YD+ S K ++K LGGA+ W L D R+ Sbjct: 358 NDTAKVPYLYNASNKRFISYDDAESVGYKTAYIKSKGLGGAMFWELSGD---------RN 408 Query: 377 FPLTSTLKGDL 387 L + LK DL Sbjct: 409 KTLQNKLKADL 419 >6BT9-A nrPDB Length = 672 Score = 349 bits (896), Expect = 1e-96, Method: Composition-based stats. Identities = 117/441 (26%), Positives = 189/441 (42%), Gaps = 80/441 (18%) Query: 21 SYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGM------------------- 61 S +++ Y+ SW +++ +ID THL YAFA + Sbjct: 36 SQKIVGYFPSWGVY---GRNYQVADIDASKLTHLNYAFADICWNGKHGNPSTHPDNPNKQ 92 Query: 62 -----------QNNEI----------------------TYTHEQDL----RDYEALNGLK 84 QN E+ T + D ++ L LK Sbjct: 93 TWNCKESGVPLQNKEVPNGTLVLGEPWADVTKSYPVSGTTWEDCDKYARCGNFGELKRLK 152 Query: 85 DKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGS 144 K LKT++++GGW + FS M + + R++F +S + FLR Y FDG++LDW+YPG Sbjct: 153 AKYPHLKTIISVGGWTWSNR-FSDMAADEKTRKVFAESTVAFLRAYGFDGVDLDWEYPGV 211 Query: 145 RGSP-----PKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPE 199 P P+DK F++L++++R A + E LL ++GA ++ + Sbjct: 212 ETIPGGSYRPEDKQNFTLLLQDVRNALNKAGAEDGKQYLLTIASGAS--QRYADHTELKK 269 Query: 200 LSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEK 259 +SQ LD+I +MTYD H + + N+ LYK P D + + VD I+ + + G +K Sbjct: 270 ISQILDWINIMTYDFHGGWEATSNHNAALYKDPNDPAANTNFYVDGAINVYTNEGVPVDK 329 Query: 260 LIVGFPAYGHTFILSDPSKTGIGAP--------TISTGPPGKY-TDESGLLAYYEV-CTF 309 L++G P YG + G P S G Y T ++G+ Y ++ + Sbjct: 330 LVLGVPFYGRGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVYDYGDLAANY 389 Query: 310 LN-EGATEVWDAPQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 +N G W+ +VPY Y ++ YD+ S K K ++K L GA+ W L D Sbjct: 390 VNKNGFVRYWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWELSGDC 449 Query: 367 FSGSFCHQRHFPLTSTLKGDL 387 + L TL +L Sbjct: 450 RTSPKYSCSGPKLLDTLVKEL 470 >5GZU-A nrPDB Length = 885 Score = 329 bits (844), Expect = 1e-90, Method: Composition-based stats. Identities = 108/382 (28%), Positives = 177/382 (46%), Gaps = 54/382 (14%) Query: 23 QLMCY---YTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYT---------- 69 +++ Y + WAKD +D THL YAF + N ++ Sbjct: 27 KIVSYIPAWVDWAKDERG--------VDATKFTHLYYAFGRINNGKVVTIKEDAKWTEDP 78 Query: 70 -----------HEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQI 118 + D + L GLK KN LK L++IGGW+ FS TP++R++ Sbjct: 79 TITEADRIKRRNNPDESNLAYLTGLKAKNPNLKVLVSIGGWE--AEGFSDAALTPESREV 136 Query: 119 FIQSVIRFLRQYNFDGLNLDWQYP-----GSRGSPPKDKHLFSVLVKEMRKAFEEESVEK 173 F S + F+ +YN DG++LDW+YP G S P+DK F+ L+K +R+ + +S Sbjct: 137 FANSALDFMNKYNLDGIDLDWEYPVYGAWGVIKSRPEDKANFTALLKLLREKLDAQSTTT 196 Query: 174 DIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPY 233 + L + AG ++ +++ LDYI +MTYDLH D T ++ +Y + Sbjct: 197 NKYYEL--AIAAGASKTYTDSVELTKITPYLDYINLMTYDLHGGWDPATSHHTAVYSATN 254 Query: 234 DIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGK 293 + L+VDS + + ++G +EKL+VG Y + + TG+ + G Sbjct: 255 N-----QLSVDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGL------SEKAGS 303 Query: 294 YTDESGLLAYYE-VCTFLN-EGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKD 351 G + Y E V ++N G T WD + PY + G+ ++ Y++ S KA+++K Sbjct: 304 QAGSPGTIVYSELVNNYINKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQ 363 Query: 352 NNLGGAVVWPLDMDDFSGSFCH 373 NNL G + W D S + Sbjct: 364 NNLAGFMYWEYSQDSDSHELAN 385 Score = 305 bits (780), Expect = 3e-83, Method: Composition-based stats. Identities = 99/372 (26%), Positives = 159/372 (42%), Gaps = 48/372 (12%) Query: 24 LMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHE------------ 71 L+ Y W +D TH+ YAFA +++N++ E Sbjct: 515 LLGYVPGWVDWTNSAYK-----VDATKLTHINYAFARIKDNKVVKISEDINWVNEFPSEE 569 Query: 72 --------QDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSV 123 D ++ L LK +N LK L++IGGW FS TP+ R+ S Sbjct: 570 IREQRRNNPDDANFAYLKTLKQQNPSLKVLVSIGGW--AAEGFSDAALTPETREELANSA 627 Query: 124 IRFLRQYNFDGLNLDWQYP-----GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRL 178 I F+ QY FDG++LDW+YP G S P+DK F+ L+K R+ + E Sbjct: 628 IAFMHQYGFDGIDLDWEYPVYGAFGVIKSRPEDKQNFTALLKLFREKLDVEGALHGKYYE 687 Query: 179 LLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKS 238 L + + + + ++ ++ Q LDY+ VMTYD H + T + +Y S G Sbjct: 688 L--AIASAAAPIYINSVELDKIHQYLDYMSVMTYDYHGSWESKTAHQASVYTSALSPG-- 743 Query: 239 ADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDES 298 D + DS+++ ++ G + KL++G Y ++ G+ G Sbjct: 744 -DFSADSVLTAYRKQGVPASKLVIGGAFYARGWVNVPNINHGLFQ------QAGDQAKNP 796 Query: 299 GLLAYYE-VCTFLNEGATEVWDAPQEVPYAY----QGNEWVGYDNVRSFKLKAQWLKDNN 353 G Y + V + ++G T WD + PY Y G ++ YD+ S K KA++ K+ Sbjct: 797 GTPTYNDLVKDYFDKGYTRYWDNSAKAPYLYNPDANGGTFITYDDEESLKYKAEYAKNQG 856 Query: 354 LGGAVVWPLDMD 365 L G + W D Sbjct: 857 LRGVMFWDYSQD 868 >3AQU-A nrPDB Length = 356 Score = 328 bits (840), Expect = 3e-90, Method: Composition-based stats. Identities = 103/333 (30%), Positives = 161/333 (48%), Gaps = 18/333 (5%) Query: 41 FKPGNIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 98 F +ID L THL AFA + Q N++T + + ++ +N +KTLL+IGG Sbjct: 16 FPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGG 75 Query: 99 WKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVL 158 +++M S P +R+ FI S IR R Y F GL+LDW+YP S + F L Sbjct: 76 GIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----ATEMTNFGTL 131 Query: 159 VKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDP- 217 ++E R A E+ PRLLL + + Y + ++ SLD++ +M YD + P Sbjct: 132 LREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPG 191 Query: 218 KDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPS 277 TG + L+ P + G S D+ W G ++K ++GFP YG+ + L++ + Sbjct: 192 WSRVTGPPAALF-DPSNAGPSG----DAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNAN 246 Query: 278 KTGIGAPTISTGPPGKYTDESGLLAYYEVCTFL-NEGATEVWDAPQEVPYAYQGNEWVGY 336 APT G + Y ++ F+ + GAT V+++ Y Y G W+GY Sbjct: 247 SHSYYAPTTGAAIS-----PDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGY 301 Query: 337 DNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSG 369 D+ +S K ++ K L G W + DD SG Sbjct: 302 DDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSG 334 >5GQB-A nrPDB Length = 553 Score = 327 bits (838), Expect = 5e-90, Method: Composition-based stats. Identities = 93/348 (26%), Positives = 158/348 (45%), Gaps = 23/348 (6%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + IEGSF+ G D + H +A ++ +E ++ L LK Sbjct: 198 KEIEGSFQALQRSCSGREDFKVSIHDPWAALQKPQKGLSSWNEPYKGNFGQLMMLKQAKP 257 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYN-FDGLNLDWQYPGSRG- 146 +LK L +IGGW F + R+ F+ SV FL+ + FDG+++DW++PG +G Sbjct: 258 DLKILPSIGGWTLADPFFFF--TDETKRRRFVASVKDFLQTWKFFDGVDIDWEFPGGKGA 315 Query: 147 ----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 PKD ++ +L+KE+R+ E S E L ++ AG + Y + + Sbjct: 316 NPNLGSPKDGEIYVLLMKELREMLNELSAETGRKYELTSAISAGWDKIQVVDYSAAQ--K 373 Query: 203 SLDYIQVMTYDLHDPKDGYT-GENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 +D+I M+YD T G + LY D + D + + G + +K++ Sbjct: 374 YMDHIFFMSYDFKGAWSNDTLGHQASLYAP--DWNEKETYTTDFGVQFLLAQGVSPKKIV 431 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATE-VWDA 320 VG YG + K +TG P K T + G++ Y E+ T + +G E +D Sbjct: 432 VGVAMYGRGWTGVHGYKDNNPFTGNATG-PVKGTWQDGVVDYREIATEIAQGKWEYHYDK 490 Query: 321 PQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 + PY ++ + + YD+ RS K ++++ N LGG W +D D+ Sbjct: 491 VAQAPYVFRPATGDLITYDDARSTIEKGKYVRANKLGGLFAWEIDADN 538 >6EPB-A nrPDB Length = 423 Score = 324 bits (830), Expect = 5e-89, Method: Composition-based stats. Identities = 91/368 (24%), Positives = 160/368 (43%), Gaps = 40/368 (10%) Query: 19 GSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRD-- 76 + Y Y+T+W + +F+P ++ TH+IY+F +Q + + + Sbjct: 35 ANGYANSVYFTNWGIY---DRNFQPADLVASDVTHVIYSFMNLQADGTVISGDTYADYEK 91 Query: 77 -----------------YEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIF 119 + L +K N LK LL+IGGW + F + ST NR+ F Sbjct: 92 HYADDSWNDVGTNAYGCVKQLFKVKKANRGLKVLLSIGGWTW-STNFPSAASTDANRKNF 150 Query: 120 IQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLL 179 ++ I F++ + FDG+++DW+YP + +L+KE+R + + + Sbjct: 151 AKTAITFMKDWGFDGIDIDWEYP----ADATQASNMILLLKEVRSQLDAYAAQYAPGYHF 206 Query: 180 LTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSA 239 L + A S ++ +L Q LDYI +M YD TG ++ L+ +P + + Sbjct: 207 LLTIAAPAGKDNYSKLRLADLGQVLDYINLMAYDYAGSFSPLTGHDANLFNNPSNP-NAT 265 Query: 240 DLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESG 299 N DS + + + G + K+++G P YG +F + GIG G + E+G Sbjct: 266 PFNTDSAVKDYINGGVPANKIVLGMPIYGRSFQ----NTAGIGQTYNG---VGSGSWEAG 318 Query: 300 LLAYYEVCTFLNEGATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGA 357 + Y + GAT +D+ + Y+Y E + +D K +LK LGG+ Sbjct: 319 IWDYKALP---KAGATVQYDSVAKGYYSYNSATKELISFDTPDMINTKVAYLKSLGLGGS 375 Query: 358 VVWPLDMD 365 + W D Sbjct: 376 MFWEASAD 383 >3G6L-A nrPDB Length = 406 Score = 320 bits (821), Expect = 5e-88, Method: Composition-based stats. Identities = 87/361 (24%), Positives = 152/361 (42%), Gaps = 40/361 (11%) Query: 26 CYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRD--------- 76 Y+T+W +F+P ++ H++Y+F ++ + Y+ + Sbjct: 25 VYFTNWGIY---GRNFQPADLQASKILHVLYSFMNLRVDGTVYSGDTYADLEKHYSDDSW 81 Query: 77 ----------YEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRF 126 + L LK N LK +L+IGGW + F A ST R F ++ + F Sbjct: 82 NDIGTNAYGCVKQLYKLKKANRSLKIMLSIGGWTW-STNFPAAASTEATRATFAKTAVEF 140 Query: 127 LRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAG 186 ++ + FDG+++DW+YP S D + +L++ +R+ + S S A Sbjct: 141 MKDWGFDGIDVDWEYPASE----TDANNMVLLLQRVRQELDSYSATYANGYHFQLSIAAP 196 Query: 187 IIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSI 246 + K+ +L LD I +M YD D +G + LY S + S + + Sbjct: 197 AGPSHYNVLKLAQLGSVLDNINLMAYDYAGSWDSVSGHQTNLYPSTSNPS-STPFSTKAA 255 Query: 247 ISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEV 306 + + G + K+I+G P YG F+ +D G G P + G + + ESG+ Y + Sbjct: 256 VDAYIAAGVPASKIILGMPIYGRAFVGTD----GPGKPYSTIG---EGSWESGIWDYKVL 308 Query: 307 CTFLNEGATEVWDAPQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDM 364 GAT + D+ Y+Y + + YD + K + K LGG++ W Sbjct: 309 P---KAGATVITDSAAGATYSYDSSSRTMISYDTPDMVRTKVSYAKGLGLGGSMFWEASA 365 Query: 365 D 365 D Sbjct: 366 D 366 >3CHF-A nrPDB Length = 433 Score = 320 bits (821), Expect = 6e-88, Method: Composition-based stats. Identities = 96/375 (25%), Positives = 162/375 (43%), Gaps = 43/375 (11%) Query: 14 LNVQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQ----------- 62 L + S Y+ + Y+ +WA + P ++ TH++YAFA ++ Sbjct: 35 LEARASSGYRSVVYFVNWAIY---GRNHNPQDLPVERLTHVLYAFANVRPETGEVYMTDS 91 Query: 63 ---------NNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTP 113 + + T + L LK +N LK LL+IGGW + P F+ ST Sbjct: 92 WADIEKHYPGDSWSDTGNNVYGCIKQLYLLKKQNRNLKVLLSIGGWTYSP-NFAPAASTD 150 Query: 114 QNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEE-SVE 172 R+ F ++ ++ L+ FDGL++DW+YP + + F +L+KE+R A + + Sbjct: 151 AGRKNFAKTAVKLLQDLGFDGLDIDWEYP----ENDQQANDFVLLLKEVRTALDSYSAAN 206 Query: 173 KDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSP 232 LLT D IK + ++ Q LD+ +M YD +G + +Y Sbjct: 207 AGGQHFLLTVASPAGPDKIKV-LHLKDMDQQLDFWNLMAYDYAGSFSSLSGHQANVYNDT 265 Query: 233 YDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPG 292 + S N + + ++ G + K+++G P YG +F +D G G P G Sbjct: 266 SNP-LSTPFNTQTALDLYRAGGVPANKIVLGMPLYGRSFANTD----GPGKPYNG---VG 317 Query: 293 KYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNE--WVGYDNVRSFKLKAQWLK 350 + + E+G+ Y + GATE Y+Y + YDN + LK+ ++K Sbjct: 318 QGSWENGVWDYKALP---QAGATEHVLPDIMASYSYDATNKFLISYDNPQVANLKSGYIK 374 Query: 351 DNNLGGAVVWPLDMD 365 LGGA+ W D Sbjct: 375 SLGLGGAMWWDSSSD 389 >3ALF-A nrPDB Length = 353 Score = 319 bits (818), Expect = 1e-87, Method: Composition-based stats. Identities = 96/330 (29%), Positives = 152/330 (46%), Gaps = 17/330 (5%) Query: 45 NIDPCLCTHLIYAFAGMQN--NEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFG 102 NID L THL AFA + N++ + E + + ++ KN +KT L+I G + Sbjct: 19 NIDSTLFTHLFCAFADLNPQLNQLIISPENQDSFRQFTSTVQRKNPSVKTFLSIAGGRAN 78 Query: 103 PAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEM 162 + M P +R+ FI S IR RQ F GL+LDW+YP S D L+ E Sbjct: 79 STAYGIMARQPNSRKSFIDSSIRLARQLGFHGLDLDWEYPLS----AADMTNLGTLLNEW 134 Query: 163 RKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDP--KDG 220 R A E+ LLLT+ + V Y + L+++LD+I +M YD + P Sbjct: 135 RTAINTEARNSGRAALLLTAAVSNSPRVNGLNYPVESLARNLDWINLMAYDFYGPNWSPS 194 Query: 221 YTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTG 280 T ++ L+ + S +N W G ++KL++G P YG+ + L + + G Sbjct: 195 QTNSHAQLFDPVNHVSGSDGINA------WIQAGVPTKKLVLGIPFYGYAWRLVNANIHG 248 Query: 281 IGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG-ATEVWDAPQEVPYAYQGNEWVGYDNV 339 + AP G D G + Y + ++ E AT V++A Y Y G+ W+ YD+ Sbjct: 249 LRAPAAGKSNVGAVDD--GSMTYNRIRDYIVESRATTVYNATIVGDYCYSGSNWISYDDT 306 Query: 340 RSFKLKAQWLKDNNLGGAVVWPLDMDDFSG 369 ++ + K ++K L G W + D G Sbjct: 307 QTVRNKVNYVKGRGLLGYFAWHVAGDQNWG 336 >4MNK-A nrPDB Length = 348 Score = 316 bits (809), Expect = 1e-86, Method: Composition-based stats. Identities = 106/342 (30%), Positives = 162/342 (47%), Gaps = 25/342 (7%) Query: 31 WAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNN--EITYTHEQDLRDYEALNGLKDKNT 88 W F P I+ L THL YAFA + E+ + + ++ N Sbjct: 10 WPAY--SVSEFPPSKINSRLFTHLYYAFAELNAPTFEVRVPPGSEKTAEDFTPTVRRLNP 67 Query: 89 ELKTLLAIGGW-KFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGS 147 +KTL++IGG F+ + S RQ F++S I R+Y F GL+LD++YP Sbjct: 68 SVKTLISIGGGGSEVRDNFAKLNSDASARQRFVKSSIALARRYGFHGLDLDYEYP----E 123 Query: 148 PPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDV----IKSGYKIPELSQS 203 P + F LV E+ A EE+ PRLLLT + + + Y + ++ Sbjct: 124 PQLEMENFVKLVSELTAAIREEARTSGKPRLLLTEAVYFHQKLFPWEVVTEYPVQFIAAG 183 Query: 204 LDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVG 263 LD++ VM YD H + +TG + L ++ I + G EKL++G Sbjct: 184 LDWVNVMAYDFHGSWENFTGAPAAL------RDPNSKFTASVGIESFLAAGMPPEKLVLG 237 Query: 264 FPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQE 323 P +G +++L + ++ GIGAP + GP G L++ E+ F+ GA EV+D Sbjct: 238 IPLFGRSWLLKNNNEVGIGAPAVGAGPV------DGALSFSEIQNFIRGGAREVFDTTTV 291 Query: 324 VPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 YAY+ N WVGYDN +S LK Q+ K+ LGG W ++ D Sbjct: 292 SAYAYKDNVWVGYDNQQSVALKVQYAKEKRLGGYFFWSVNQD 333 >5ZL9-A nrPDB Length = 618 Score = 308 bits (788), Expect = 4e-84, Method: Composition-based stats. Identities = 92/349 (26%), Positives = 162/349 (46%), Gaps = 23/349 (6%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + IEGSF+ G D + H +A +T + ++ L LK + Sbjct: 182 KEIEGSFQALQRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHP 241 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPGSRG- 146 +LK L +IGGW PF M + R F+ SV FL+ + F DG+++DW++PG +G Sbjct: 242 DLKILPSIGGWTLSD-PFFFMGDKVK-RDRFVGSVKEFLQTWKFFDGVDIDWEFPGGKGA 299 Query: 147 ----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 P+D + +L+KE+R ++ SVE L ++ AG I Y ++Q Sbjct: 300 NPNLGSPQDGETYVLLMKELRAMLDQLSVETGRKYELTSAISAGKDK-IDKFYSFVNVAQ 358 Query: 203 S-LDYIQVMTYDLHDPKD-GYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKL 260 + +D+I +M+YD + D G + L + + ++ G K+ Sbjct: 359 NSMDHIFLMSYDFYGAFDLKNLGHQTALNAPAWKP--DTAYTTVNGVNALLAQGVKPGKI 416 Query: 261 IVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVC-TFLNEGATEVWD 319 +VG YG + + + I +TG P K T E+G++ Y ++ F++ +D Sbjct: 417 VVGTAMYGRGWTGVNGYQNNIPFTGTATG-PVKGTWENGIVDYRQIAGQFMSGEWQYTYD 475 Query: 320 APQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 A E PY ++ + + + +D+ RS + K +++ D LGG W +D D+ Sbjct: 476 ATAEAPYVFKPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSWEIDADN 524 >1LL6-A nrPDB Length = 392 Score = 304 bits (779), Expect = 4e-83, Method: Composition-based stats. Identities = 84/364 (23%), Positives = 154/364 (42%), Gaps = 36/364 (9%) Query: 21 SYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRD---- 76 ++ + Y+ +WA P ++ TH++YAFA ++ + Y + Sbjct: 2 GFRSVVYFVNWAIYGRG---HNPQDLKADQFTHILYAFANIRPSGEVYLSDTWADTDKHY 58 Query: 77 ---------------YEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQ 121 + + LK N LKTLL+IGGW + P F ST + R+ F Sbjct: 59 PGDKWDEPGNNVYGCIKQMYLLKKNNRNLKTLLSIGGWTYSP-NFKTPASTEEGRKKFAD 117 Query: 122 SVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLT 181 + ++ ++ FDG++++W+YP K + F +L+K R+A + S + + L Sbjct: 118 TSLKLMKDLGFDGIDINWEYPEDE----KQANDFVLLLKACREALDAYSAKHPNGKKFLL 173 Query: 182 STGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADL 241 + + + K+ E+ + LD+ +M YD D +G S ++ S +S Sbjct: 174 TIASPAGPQNYNKLKLAEMDKYLDFWNLMAYDFSGSWDKVSGHMSNVFPSTTKP-ESTPF 232 Query: 242 NVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLL 301 + D + + G + K+++G P YG F +D T S G + E+G+ Sbjct: 233 SSDKAVKDYIKAGVPANKIVLGMPLYGRAFASTDGIGT-------SFNGVGGGSWENGVW 285 Query: 302 AYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWP 361 Y ++ + TE+ D Y + YD V+ KA+++ N +GG + W Sbjct: 286 DYKDMPQQGAQ-VTELEDIAASYSYDKNKRYLISYDTVKIAGKKAEYITKNGMGGGMWWE 344 Query: 362 LDMD 365 D Sbjct: 345 SSSD 348 >5Z7M-A nrPDB Length = 546 Score = 301 bits (772), Expect = 3e-82, Method: Composition-based stats. Identities = 90/348 (25%), Positives = 160/348 (45%), Gaps = 23/348 (6%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + IEGSF+ G D + H +A +T + ++ L LK + Sbjct: 182 KEIEGSFQALQRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHP 241 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYN-FDGLNLDWQYPGSRG- 146 +LK L +IGGW PF M + R F+ SV FL+ + FDG+++ W++PG +G Sbjct: 242 DLKILPSIGGWTLSD-PFFFMGDKVK-RDRFVGSVKEFLQTWKFFDGVDIAWEFPGGKGA 299 Query: 147 ----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 P+D + +L+KE+R ++ SVE L ++ AG + K Y + + Sbjct: 300 NPNLGSPQDGETYVLLMKELRAMLDQLSVETGRKYELTSAISAGKDMIDKVAYNVAQ--N 357 Query: 203 SLDYIQVMTYDLHDPKD-GYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 261 S+D+I +M+YD + D G + L + + ++ G K++ Sbjct: 358 SMDHIFLMSYDFYGAADLKNLGHQTALNAPAWKP--DTAYTTVNGVNALLAQGVKPGKIV 415 Query: 262 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVC-TFLNEGATEVWDA 320 VG YG + + + I +TG P K T E+G++ Y ++ F++ +DA Sbjct: 416 VGTAMYGRGWTGVNGYQNNIPFTGTATG-PVKGTWENGIVDYRQIAGQFMSGEWQYTYDA 474 Query: 321 PQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 E PY ++ + + + +D+ RS + K +++ D LGG +D D+ Sbjct: 475 TAEAPYVFKPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSAMIDADN 522 >5DF0-A nrPDB Length = 545 Score = 297 bits (760), Expect = 6e-81, Method: Composition-based stats. Identities = 82/348 (23%), Positives = 144/348 (41%), Gaps = 24/348 (6%) Query: 35 RPIEGSFKP------GNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNT 88 + I GSF+ G D + H +A ++ +E ++ L K N Sbjct: 195 KTISGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKSVSAWNEPYKGNFGQLMAAKLANP 254 Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPGSRGS 147 LK L +IGGW PF M + R +F+ SV FL+ + F DG+++DW++PG +G+ Sbjct: 255 HLKILPSIGGWTLSD-PFYFMHDVEK-RNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGA 312 Query: 148 PPK------DKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 201 P D + +L++E+R ++ + L ++ AG + Y E Sbjct: 313 NPSLGDAERDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNY--AEAQ 370 Query: 202 QSLDYIQVMTYDLHDPKDGY-TGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKL 260 +SL I +M+YD G + +Y ++ + + G K+ Sbjct: 371 KSLGKIFLMSYDFKGAWSNTDLGYQTTVYAPSWNSEEL--YTTHYAVDALLKQGVDPNKI 428 Query: 261 IVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDA 320 IVG YG + G P T E G++ Y ++ LN +D+ Sbjct: 429 IVGVAMYGRGWTGVTNYTNDNYFSGTGNG-PVSGTWEDGVVDYRQIQKDLNN-YVYTFDS 486 Query: 321 PQEVPYAYQGN--EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 + Y + + + + +D+V S K +++ N LGG W +D D+ Sbjct: 487 AAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADN 534 >4URI-A nrPDB Length = 337 Score = 289 bits (741), Expect = 1e-78, Method: Composition-based stats. Identities = 101/330 (30%), Positives = 149/330 (45%), Gaps = 29/330 (8%) Query: 43 PGNIDPCLCTHLIYAFAGM--QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGW- 99 +I+P THL AFA + N++T + ++ KN +KTLL+IGG Sbjct: 15 VSDINPSHFTHLFCAFADLDPNTNKLTISSSNAAAFSTFTQTVRAKNPSVKTLLSIGGGG 74 Query: 100 -KFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVL 158 + A F+ M S R+ FI S I+ R+ NF GL+LDW+YP S DK F+ L Sbjct: 75 GRALAAVFANMASQASRRKSFIDSSIQLARRNNFHGLDLDWEYPSS----DIDKTNFASL 130 Query: 159 VKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKI-PELSQSLDYIQVMTYDLHDP 217 ++E R A ES P LLL++ G + Y ++ +LD++ VMTYDL+ Sbjct: 131 IREWRAAVATESSTSGTPALLLSAAVGGSDQITPLKYYPGEAIANNLDWVNVMTYDLYTS 190 Query: 218 --KDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSD 275 T +PL+ + D I+ W G KL +G P YG + LSD Sbjct: 191 DSYPTLTQPPAPLFYP------RGIFSADEGITKWIQSGVPESKLALGLPFYGFKWRLSD 244 Query: 276 PSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVG 335 P+ G+ AP KY D +N G +D+ Y ++G +W G Sbjct: 245 PNNHGLFAPATQGLGAVKYKD------------IVNTGGQVEFDSTYVTNYRFKGTDWYG 292 Query: 336 YDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 YD+ +S K + K L G W ++ D Sbjct: 293 YDDTQSISAKVAYAKQRGLFGYFAWHIEQD 322 >3ARQ-A nrPDB Length = 584 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 95/420 (22%), Positives = 156/420 (37%), Gaps = 87/420 (20%) Query: 27 YYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGM------------------------Q 62 Y+ W + N+ TH++Y F + Sbjct: 143 YFVEWGIY---GRDYTVDNMPVDNLTHILYGFIPICGPNESVKSVGGNSFNALQTACRGV 199 Query: 63 NNEITYTHEQD------------------LRDYEALNGLKDKNTELKTLLAIGGWKFGPA 104 N+ H+ +Y L LK +N +LK + +IGGW Sbjct: 200 NDYEVVIHDPWAAYQKSFPQAGHEYSTPIKGNYAMLMALKQRNPDLKIIPSIGGWTLSD- 258 Query: 105 PFSAMVSTPQNRQIFIQSVIRFLRQYNF-DGLNLDWQYPG------SRGSPPKDKHLFSV 157 PF V +NR F+ SV +FL+ + F DG+++DW++PG +G P D + Sbjct: 259 PFYDFV-DKKNRDTFVASVKKFLKTWKFYDGVDIDWEFPGGGGAAADKGDPVNDGPAYIA 317 Query: 158 LVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDP 217 L++E+R +E E L ++ G G + Y + Q +DYI MTYD + Sbjct: 318 LMRELRVMLDELEAETGRTYELTSAIGVGYDKIEDVDY--ADAVQYMDYIFAMTYDFYGG 375 Query: 218 KDGYTGENSPLYKSPY---------------DIGKSADLNVDSIISYWKDHGAASEKLIV 262 + G + LY + + K D+ I G + KL++ Sbjct: 376 WNNVPGHQTALYCGSFMRPGQCDGGGVDENGEPYKGPAYTADNGIQLLLAQGVPANKLVL 435 Query: 263 GFPAYGHTF------ILSDPSKTGIGAPTIS-TGPPGKYTDESGLLAYYEVCTFL----- 310 G YG + L+DP+ G T G + E G++ Y + +F+ Sbjct: 436 GTAMYGRGWEGVTPDTLTDPNDPMTGTATGKLKGSTAQGVWEDGVIDYKGIKSFMLGANN 495 Query: 311 --NEGATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 G +DA E P+ + E + +D+ RS K + K L G W +D D+ Sbjct: 496 TGINGFEYGYDAQAEAPWVWNRSTGELITFDDHRSVLAKGNYAKSLGLAGLFSWEIDADN 555 >3WD0-A nrPDB Length = 503 Score = 285 bits (729), Expect = 3e-77, Method: Composition-based stats. Identities = 101/421 (23%), Positives = 166/421 (39%), Gaps = 76/421 (18%) Query: 19 GSSYQLMCYY-------TSWAKDRPIEGSFKPGNIDPCL---CTHLIYAFAGMQNN-EIT 67 + ++ YY ++ + F NI P TH+ ++F + +N E Sbjct: 6 STRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKAKQLTHINFSFLDINSNLECA 65 Query: 68 Y---THEQDLRDY-EALNGLKDKNTELKTLLAIGGWKFGP------APFSAMVSTPQNRQ 117 + T++ RD L LK N L+ + +IGGW + A + V TP R Sbjct: 66 WDPATNDAKARDVVNRLTALKAHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPAART 125 Query: 118 IFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDI-- 175 F QS +R ++ Y FDG+++DW+YP + F ++E+R ++++ Sbjct: 126 KFAQSCVRIMKDYGFDGVDIDWEYP-----QAAEVDGFIAALQEIRTLLNQQTIADGRQA 180 Query: 176 -PRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYD 234 P L + G + + K+ ++ LDYI +MTYDL P + T + L+ Sbjct: 181 LPYQLTIAGAGGAFFLSRYYSKLAQIVAPLDYINLMTYDLAGPWEKITNHQAALFGDAAG 240 Query: 235 IGKSA----------------------DLNVDSII-SYWKDHGAASEKLIVGFPAYGHTF 271 L VD+ + + G S K+++G P YG F Sbjct: 241 PTFYNALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVPSAKIVMGVPFYGRAF 300 Query: 272 ILSDPSKTGIGAPTISTGPPGK----------------YTDESGLLAYYEVCTFL---NE 312 G G S PG+ D+ +A Y + N Sbjct: 301 KGVSG---GNGGQYSSHSTPGEDPYPNADYWLVGCDECVRDKDPRIASYRQLEQMLQGNY 357 Query: 313 GATEVWDAPQEVPYAY--QGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGS 370 G +W+ + PY Y Q +V YD+ SFK KA+++K LGG + W L D+ +G Sbjct: 358 GYQRLWNDKTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVMFWHLGQDNRNGD 417 Query: 371 F 371 Sbjct: 418 L 418 >6F8N-A nrPDB Length = 414 Score = 281 bits (720), Expect = 3e-76, Method: Composition-based stats. Identities = 107/404 (26%), Positives = 173/404 (42%), Gaps = 63/404 (15%) Query: 19 GSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEI------------ 66 +SY + Y+ G +D THL Y+F + N+E Sbjct: 8 AASYLSVGYFNGGGDVTAGPGG-DINKLDVTQITHLNYSFGLIYNDEKQETNPALKDPSR 66 Query: 67 ---TYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSV 123 Y + + D + L L+ +N ELK LL++GGW G FS +T ++R +FI+SV Sbjct: 67 LHQIYLSPKVMADLQLLPVLRKQNPELKVLLSVGGW--GARGFSGAAATAESRAVFIRSV 124 Query: 124 IRFLRQYNFDGLNLDWQYP-----GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRL 178 + ++QY+ DG++LDWQYP G S P D+ F++L+ E+ KA + +L Sbjct: 125 QQVIKQYHLDGIDLDWQYPVNGAWGLVESQPADRANFTLLLAELHKALD-------KGKL 177 Query: 179 LLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPY--DIG 236 L + GA + + + ++ LDYI +MTYD+ G NS LY S + Sbjct: 178 LTIAVGAN-VKSPQEWVDVKGIAPYLDYINLMTYDMA---YGTQYFNSNLYDSKQWPTVA 233 Query: 237 KSADLNVDSIISYWKDHGAASEKLIVGFPAYGH----------TFILSDPSKTGIGAPTI 286 + + + ++ + G +L +G YG + +D +K + P Sbjct: 234 AADRYSANFVVDNYLAAGLKPAQLNLGIGFYGRVPKRATEPGIDWDKADAAKNPVTQPYF 293 Query: 287 STGPPGKY-------TDESGLLAYYEVCTFLNEG---ATEVWDAPQEVPYAYQGNE---- 332 + + T +S V LN+ T WD+ +VPY + Sbjct: 294 TARETAVFKAMGLDLTKDSYFKYNDIVSKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKP 353 Query: 333 --WVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQ 374 + Y+N RS LKA ++K LGGA+ W DD + HQ Sbjct: 354 LFAISYENPRSVALKADYIKSKGLGGAMFWEYGADD-NNRLAHQ 396 >1KFW-A nrPDB Length = 435 Score = 281 bits (720), Expect = 3e-76, Method: Composition-based stats. Identities = 91/424 (21%), Positives = 153/424 (36%), Gaps = 83/424 (19%) Query: 20 SSYQLMCYYTSWAKDRPIEGSFKPGNIDPC----LCTHLIYAFAGMQNNEIT-------- 67 + Y+ + Y+ W +F+ +D TH+ Y+F + N +T Sbjct: 7 NGYRNVGYFAQWGVY---GRAFQAKQLDVSGTAKNLTHINYSFGNINNQTLTCFMANKAQ 63 Query: 68 --------------------------------YTHEQDLRDYEALNGLKDKNTELKTLLA 95 + + L LK KN +LK +++ Sbjct: 64 GTGPNGSDGAGDAWADFGMGYAADKSVSGKADTWDQPLAGSFNQLKQLKAKNPKLKVMIS 123 Query: 96 IGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYN----------------FDGLNLDW 139 +GGW + FS +T +RQ + S I + N FDG+++DW Sbjct: 124 LGGWTW-SKNFSKAAATEASRQKLVSSCIDLYIKGNLPNFEGRGGAGAAAGIFDGIDIDW 182 Query: 140 QYPGSRGS-------PPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK 192 ++PG+ D+ F L+ E RK + + +L A D+ Sbjct: 183 EWPGTNSGLAGNGVDTVNDRANFKALLAEFRKQLDAYGSTNNKKYVLSAFLPANPADIDA 242 Query: 193 SGYKIPELSQSLDYIQVMTYDLHDPKDGY-TGENSPLYKSPYDI-GKSADLNVDSIISYW 250 G+ P +SLD+ + YDLH + TG + LY P D S + D + + Sbjct: 243 GGWDDPANFKSLDFGSIQGYDLHGAWNPTLTGHQANLYDDPADPRAPSKKFSADKAVKKY 302 Query: 251 KDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFL 310 G ++L +G AYG + + P T E+ Y ++ T Sbjct: 303 LAAGIDPKQLGLGLAAYGRGWTGAKNVSP--WGPATDG---APGTYETANEDYDKLKTL- 356 Query: 311 NEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGS 370 T+ +DA + Y G +W YDN+ + K K ++ LGG + W L D +G Sbjct: 357 ---GTDHYDAATGSAWRYDGTQWWSYDNIATTKQKTDYIVSKGLGGGMWWELSGD-RNGE 412 Query: 371 FCHQ 374 Sbjct: 413 LVGA 416 >1JNE-A nrPDB Length = 420 Score = 281 bits (719), Expect = 4e-76, Method: Composition-based stats. Identities = 103/421 (24%), Positives = 177/421 (42%), Gaps = 59/421 (14%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCL--CTHLIYAFAGMQNNEITYTH-----EQDLR 75 L+CYY S + R G +++ L C+HL+Y +AG++ + + Sbjct: 3 NLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKH 62 Query: 76 DYEALNGLKDKNTELKTLLAIGGWKF----GPAPFSAMVSTPQNRQI-FIQSVIRFLRQY 130 + + LK K LK LL++GG P + ++ + RQI FI+S ++ Y Sbjct: 63 QFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYELVKTY 122 Query: 131 NFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESV---EKDIPRLLLTSTGAGI 187 FDGL+L +Q+P + P K + K ++K F + + + + T+ + Sbjct: 123 GFDGLDLAYQFP--KNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDV 180 Query: 188 IDVIKSG-----------------YKIPELSQSLDYIQVMTYDLHDPKDG--YTGENSPL 228 D +++ + IP L+ +D++ + T+D P ++P+ Sbjct: 181 KDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPI 240 Query: 229 YKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILS-DPSKTGIGAPTIS 287 Y + A LN D + YW G S K+ +G YG+ + L+ D G+ + Sbjct: 241 YHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPET 300 Query: 288 TGPP--GKYTDESGLLAYYEVCTFLNEG-----------------ATEVWDAPQEVPYAY 328 +GP G + + GLL+Y E+C L+ T+ + P Sbjct: 301 SGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDG 360 Query: 329 QGNE--WVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLKGD 386 Q E WV YD+ S KA + + NLGG ++ L DDF G C +P+ +K Sbjct: 361 QITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPILRAIKYR 419 Query: 387 L 387 L Sbjct: 420 L 420 >3QOK-A nrPDB Length = 420 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 93/391 (23%), Positives = 163/391 (41%), Gaps = 62/391 (15%) Query: 24 LMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEIT---------------Y 68 + Y+ G +D THL Y+F + N+E + Sbjct: 28 SVGYFNGGGDVTAGPGG-DIDKLDVRQITHLNYSFGLIYNDEKDETNAALKDPAHLHEIW 86 Query: 69 THEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLR 128 + D + L L+ +N +LK LL++GGW G FS +T ++R +FI+S + ++ Sbjct: 87 LSPKVQADLQKLPALRKQNPDLKVLLSVGGW--GARGFSGAAATAESRAVFIRSAQKIIQ 144 Query: 129 QYNFDGLNLDWQYP-----GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTST 183 QY DG++LDW++P G S P D+ F+ L+K +R+A +L+ + Sbjct: 145 QYGLDGIDLDWEFPVNGAWGLVASQPADRDNFTALLKSLREAV-------GEQKLVTIAV 197 Query: 184 GAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPY--DIGKSADL 241 GA + KS + ++ L+YI +MTYD+ G NS LY S + + + Sbjct: 198 GANA-ESPKSWVDVKAVAPVLNYINLMTYDMA---YGTQYFNSNLYDSSHWPTVAAADKY 253 Query: 242 NVDSIISYWKDHGAASEKLIVGFPAYGH----------TFILSDPSKTGIGAPTISTGPP 291 + D +++ + G ++ +G YG + +D + P Sbjct: 254 SADFVVNNYLAAGLKPSQMNLGIGFYGRVPKRAVEPGIDWTKADAQNNPVTQPYFGPQQI 313 Query: 292 GKYT------DESGLLAYYEVCTFL----NEGATEVWDAPQEVPYA----YQGNEW--VG 335 + + + Y ++ L + TE WD +VP+ +G + Sbjct: 314 ALFASLGYDLSKDTYVKYNDIVGKLLNDPQKRFTEHWDDEAKVPWLSVQSAEGKPLFALS 373 Query: 336 YDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 Y+N RS +KA ++K L GA+ W DD Sbjct: 374 YENPRSVAIKADYIKAKGLAGAMFWEYGADD 404 >4W5U-B nrPDB Length = 408 Score = 263 bits (673), Expect = 8e-71, Method: Composition-based stats. Identities = 88/382 (23%), Positives = 134/382 (35%), Gaps = 61/382 (15%) Query: 25 MCYYTSWAKDRPIEGSFKPGNID----PCLCTHLIYAFAGMQNNEI-------------- 66 + Y+T W + +F N+D TH+ YAF + + Sbjct: 44 LGYFTEWGTY---DRNFNVKNLDTSGTAAKITHINYAFGNVTGGKCAIGDSYADYDKAFT 100 Query: 67 ---------TYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQ 117 + ++ L LK K +K L + GGW + F+ PQ Sbjct: 101 ADQSVSGQADTWDQPLRGNFNQLRQLKAKYPHIKVLWSFGGWTW-SGGFADAAKDPQG-- 157 Query: 118 IFIQSVIRFLRQYN----FDGLNLDWQYPGSRG--SPPKDKHLFSVLVKEMRKAFEEESV 171 F QS + FDG+++DW+YP + G F L+ +R F +E V Sbjct: 158 -FAQSCYNLVHDPRWDGVFDGIDIDWEYPNACGLTCDSSGPDAFRNLMAALRSTFGDELV 216 Query: 172 EKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKD--GYTGENSPLY 229 +T+ G + + Y +Q +D+ VMTYD D G T +SPL Sbjct: 217 TAA-----VTADGTPGGKIEATDY--AGAAQYVDWYNVMTYDFFGAWDAQGPTAPHSPL- 268 Query: 230 KSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTG 289 + YD I+ +K G ++KL++G YG + AP + Sbjct: 269 -TSYDGIPKQGFTSADAIAAFKAQGVPADKLLLGIGFYGRGWTGVTQ-----DAPGGTAT 322 Query: 290 PPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWL 349 P T E G+ Y + V YA+ G+ YD + K W Sbjct: 323 GPAAGTWEQGIEDYKVLKN-----TCPVTGTVAGTAYAHCGSNLWSYDTPDTIASKMAWA 377 Query: 350 KDNNLGGAVVWPLDMDDFSGSF 371 D L GA W D G Sbjct: 378 NDQGLRGAFAWDFSGDTADGEL 399 >4TXG-A nrPDB Length = 793 Score = 258 bits (659), Expect = 4e-69, Method: Composition-based stats. Identities = 88/466 (18%), Positives = 156/466 (33%), Gaps = 127/466 (27%) Query: 19 GSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHE------- 71 GS +++ Y+TSW + ++ +I TH+ YAFA + + +E Sbjct: 151 GSRRRIIGYFTSWRTGKDGSPAYLASDIPWSKLTHINYAFAHVDGSNKLSVNETAPGNPA 210 Query: 72 -----------------QDLRDYEALNGLKDKNTELKTLLAIGGW------------KFG 102 + L K K +KTL+++GGW + Sbjct: 211 TDMSWPGVAGAEMDASLPYKGHFNLLTQYKRKYPGVKTLISVGGWAETGGYFDANGKRVA 270 Query: 103 PAPFSAMVSTPQNR------QIFIQSVIRFLRQYNFDGLNLDWQYPGSRG--SPPKDKH- 153 F +M F S + FLR+Y FDG+++D++YP S P D Sbjct: 271 SGGFYSMTVNADGTVNQAGINAFSDSAVAFLRKYGFDGVDIDFEYPTSMNNAGNPLDWTF 330 Query: 154 ----------LFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS-- 201 + L++ +R + + + + + A SGY + + Sbjct: 331 SNARLGSLNKGYVALLQTLRDRLDRAAAQDGRYYQITAAVPA-------SGYLLRGMETF 383 Query: 202 ---QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDI-------------GKSADLNVDS 245 + LD++ VM+YDLH + + G N+ LY D G LN D Sbjct: 384 QGLKYLDFVNVMSYDLHGAWNRFVGPNAALYDDGKDAELAFWNVYSTPQYGNIGYLNTDW 443 Query: 246 IISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTD--------- 296 Y+ G + ++ +G P Y + G+ ++ + P T+ Sbjct: 444 AYHYY-RGGLPASRVNMGVPYYTRGWKNVSGGSNGLWGSSVGSNCPAGLTECGDGAVGID 502 Query: 297 --------------------------ESGLLAYYEVC---------TFLNEGATEVWDAP 321 E GL Y L ++ Sbjct: 503 NIWHDLDDSGKEIPGGSNPMWHAKNLEKGLAGSYLAAYGIDPTLPINQLTGSYQRNYNGA 562 Query: 322 QEVPYAYQGNE--WVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMD 365 P+ + + ++ ++ +S KA W+ NN+GG + W L D Sbjct: 563 LAAPWLWNAGKKVFLSTEDEQSIAQKAAWIDANNVGGVMFWELAGD 608 >5XWF-A nrPDB Length = 378 Score = 250 bits (638), Expect = 9e-67, Method: Composition-based stats. Identities = 96/379 (25%), Positives = 167/379 (44%), Gaps = 44/379 (11%) Query: 23 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAG-MQNNEITYTHEQDLRDYEALN 81 +L Y W P +I H++YAFA ++ E++ + L+ Sbjct: 3 KLSAYVVDWD---------LPKSIAWDKLDHIVYAFAEPTKDGELSGFTDSQLKSV---- 49 Query: 82 GLKDKNTELK-TLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQ 140 +++ ++ K L++GGW G FS ++ + + F+ +++ +++Y+ DGLNLDW+ Sbjct: 50 -VQEAHSRGKSISLSVGGWT-GSLYFSDLLKSSSSFDNFVSNLVDVVKEYDLDGLNLDWE 107 Query: 141 YPGS---RGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKI 197 YP S KD++ + +K + KA E+ K I + + + S Sbjct: 108 YPNSPNGVACNSKDENDTANYLK-LFKALREKLGSKTILTTAVPTAPFNDENQQPSTKLD 166 Query: 198 PELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAAS 257 + ++D +M YD++ +D G N+PLY SP G D + W G + Sbjct: 167 DNWASTVDAFYIMAYDVNGIRDKNAGANAPLYYSPKVTGVEPTSGND-AVKAWIAAGIPA 225 Query: 258 EKLIVGFPAYGHTFILSDP--SKTGIGAPTI-STGPPGKYTDE-------SGLLAY---Y 304 E+L++G P YG +P + TG+ P S+ G TDE + + Y Y Sbjct: 226 EQLVLGVPFYGRVSKTLEPITASTGLYVPISQSSQIKGDSTDEKAADPCPNAVATYSGQY 285 Query: 305 EVCTFLNEG-------ATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLG 355 T EG WD + PYAY G++ + +D+ S + K + K LG Sbjct: 286 IWRTIAQEGIARNSSGWVTYWDDISKTPYAYSFSGSKVLSFDDAASLQDKVDYAKKQGLG 345 Query: 356 GAVVWPLDMDDFSGSFCHQ 374 G ++W L+MDD + + Sbjct: 346 GVMLWSLEMDDDENTLLNA 364 >4A5Q-A nrPDB Length = 546 Score = 232 bits (591), Expect = 3e-61, Method: Composition-based stats. Identities = 82/376 (21%), Positives = 146/376 (38%), Gaps = 44/376 (11%) Query: 39 GSFKPGNIDPCLCTHLIYAFAGMQNN--EITYTHEQDLRDYEALNGLKDKNTELKTLLAI 96 G P + D + + F + Y E+ L + + EL+ L+I Sbjct: 157 GKTIPVDPDGAVLASINCGFTKWEAGDANERYNQEKAKGLLGGFRLLHEADKELEFSLSI 216 Query: 97 GGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY-NFDGLNLDWQYPGSRGS----PPKD 151 GGW FS + R F++ + F +++ F L++DW+YPGS G+ P D Sbjct: 217 GGWSM-SGLFSEIAKDEILRTNFVEGIKDFFQRFPMFSHLDIDWEYPGSIGAGNPNSPDD 275 Query: 152 KHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPEL-SQSLDYIQVM 210 F++L++++ A I L S + IP L + I +M Sbjct: 276 GANFAILIQQITDA--------KISNLKGISIASSADPAKIDAANIPALMDAGVTGINLM 327 Query: 211 TYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKD-HGAASEKLIVGFPAYGH 269 TYD DG ++ +Y+ P D+ + ++D +++ D + + +G+ Y Sbjct: 328 TYDFFTLGDGKLSHHTNIYRDPSDV--YSKYSIDDAVTHLIDEKKVDPKAIFIGYAGYTR 385 Query: 270 TFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYE---------VCTFLN-------EG 313 + T + G YTD + L +E +C +++ G Sbjct: 386 NAKNA----TITTSIPSEEALKGTYTDANQTLGSFEYSVLEWTDIICHYMDFEKGEGRNG 441 Query: 314 ATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSF 371 V D + Y Y ++ D RS + K +++KD LGG +W D D+ G Sbjct: 442 YKLVHDKVAKADYLYSEATKVFISLDTPRSVRDKGRYVKDKGLGGLFIWSGDQDN--GIL 499 Query: 372 CHQRHFPLTSTLKGDL 387 + H L +K + Sbjct: 500 TNAAHEGLKRRIKNKV 515 >4DWS-C nrPDB Length = 546 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 80/333 (24%), Positives = 136/333 (40%), Gaps = 27/333 (8%) Query: 68 YTHEQDLRDYEALNGLKDK----NTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSV 123 Y + L L+ K +L +IGGW FSA+ P R++F+ SV Sbjct: 186 YQQNRAAGLLGGLRELQKKAHAMGHKLDLAFSIGGWSLSS-YFSALAENPDERRVFVASV 244 Query: 124 IRFLRQY-NFDGLNLDWQYPGSRG-----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPR 177 + F ++ F +++DW+YPG G S KD + +L+KE+R A + + + Sbjct: 245 VDFFVRFPMFSCVDIDWEYPGGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNR-K 303 Query: 178 LLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDP-KDGYTGENSPLYKSPYDIG 236 + + + KS ++ LD I +M+YD Y G ++ LY SP D G Sbjct: 304 EISIACSGVKAKLKKSNID-QLVANGLDNIYLMSYDFFGTIWADYIGHHTNLY-SPKDPG 361 Query: 237 KSA--DLNVDSIISYWKDH-GAASEKLIVGFPAYGHTFILSDPS-----KTGIGAPTIST 288 + DL+ ++ I Y + G EK+ +G+ YG + + D + K G T+ Sbjct: 362 EQELFDLSAEAAIDYLHNELGIPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMEN 421 Query: 289 GPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKA 346 G P + + + G + D + + + ++ D R+ K K Sbjct: 422 GAPEFFDIVKNYMDAEHSLSMGKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKG 481 Query: 347 QWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPL 379 ++ N LGG W D D G + L Sbjct: 482 EYAAKNKLGGVFSWSGDQD--CGLLANAAREGL 512 >6OGD-C nrPDB Length = 633 Score = 227 bits (579), Expect = 6e-60, Method: Composition-based stats. Identities = 76/308 (24%), Positives = 130/308 (42%), Gaps = 23/308 (7%) Query: 89 ELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQY-NFDGLNLDWQYPGSRG- 146 +L +IGGW FSA+ P R++F+ SV+ F ++ F +++DW+YPG G Sbjct: 298 KLDLAFSIGGWSLSS-YFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGD 356 Query: 147 ----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 202 S KD + +L+KE+R A + + + + + + KS ++ Sbjct: 357 EGNISSDKDGENYVLLIKELRSALDSRFGYSNR-KEISIACSGVKAKLKKSNID-QLVAN 414 Query: 203 SLDYIQVMTYDLHDP-KDGYTGENSPLYKSPYDIGKSA--DLNVDSIISYWKDH-GAASE 258 LD I +M+YD Y G ++ LY SP D G+ DL+ ++ I Y + G E Sbjct: 415 GLDNIYLMSYDFFGTIWADYIGHHTNLY-SPKDPGEQELFDLSAEAAIDYLHNELGIPME 473 Query: 259 KLIVGFPAYGHTFILSDPS-----KTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG 313 K+ +G+ YG + + D + K G T+ G P + + + G Sbjct: 474 KIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSMGKNG 533 Query: 314 ATEVWDAPQEVPYAYQ--GNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSF 371 + D + + + ++ D R+ K K ++ N LGG W D D G Sbjct: 534 FVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD--CGLL 591 Query: 372 CHQRHFPL 379 + L Sbjct: 592 ANAAREGL 599 >4Q6T-A nrPDB Length = 351 Score = 155 bits (393), Expect = 2e-38, Method: Composition-based stats. Identities = 57/274 (20%), Positives = 103/274 (37%), Gaps = 32/274 (11%) Query: 99 WKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVL 158 F PA ++++ ++ +++ ++ F G+NLD++ P+++ F Sbjct: 81 GAFDPAISHSILNDRALSAGTVKQLVKLAKEGGFAGINLDFE-----KVEPRNRAAFCAF 135 Query: 159 VKEMRKAFEEESVEKDIPRLLLTSTGAGIIDV---IKSGYKIPELSQSLDYIQVMTYDLH 215 VK + A + + L+ S + D GY L ++DY QVMTYD Sbjct: 136 VKTLGNALHASN------KKLIISIPPKLSDTEPEYLQGYDYKALGAAVDYFQVMTYDQV 189 Query: 216 DP---KDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFI 272 P G+ E P +S +D + +++SY + K++ G P YG + Sbjct: 190 GPGWSSGGFHNEAWPGPESGFDWQQ-------ALLSYAVSR-VPASKVLAGLPTYGQDYS 241 Query: 273 LSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNE 332 + + I+ + D + Y D + P Q Sbjct: 242 IGNRVHWSAYQEIIAEHRAAIHRDAASATPYATW-----GPVKSFVDGVEWTPERAQPVL 296 Query: 333 WVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 W YD+ S K K + LGG VW + ++ Sbjct: 297 W--YDDAASIKTKTALVTRLGLGGTSVWAMGYEN 328 >4WIW-A nrPDB Length = 349 Score = 144 bits (364), Expect = 6e-35, Method: Composition-based stats. Identities = 66/334 (19%), Positives = 129/334 (38%), Gaps = 49/334 (14%) Query: 62 QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQ 121 + + ++ +Y+ L + +K L I G A + ++ +P R+ I Sbjct: 47 TDGSLKLVWDEGSSNYKQLTNM-AHGLGMKVLPLING---SGATLNTLLKSPAAREKLIG 102 Query: 122 SVIRFLRQYNFDGLNLDWQYPGSRG--SPPKD--KHLFSVLVKEMRKAFEEESVEKDIPR 177 ++ L+ N DG+ +D++ P G P D ++ + ++ + + + + Sbjct: 103 EIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAV 162 Query: 178 LLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGK 237 + S+ +D Y LS ++DY+ VMTYD H T P+ P+ Sbjct: 163 MPRMSSSQYWLDA----YDYEALSHAVDYLHVMTYDHHYR----TSAPGPIAPYPW---- 210 Query: 238 SADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDE 297 + +++Y + G K+++G P YG +++ K G PT ++ G Y+ Sbjct: 211 -----IKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVD--GKDANGNPTYNSTAFG-YSKA 262 Query: 298 SGLLAYYEVCTFLNEGATEVW------DAPQEVPYAYQGNEWVG----YDNVRSFKLKAQ 347 L Y GAT + D + Y + V +D+ S+ K Sbjct: 263 LELADSY--------GATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLS 314 Query: 348 WLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 381 + + L G W + D + + FPL + Sbjct: 315 IINEFGLAGVGPWAMGWVDEN---TAEGLFPLLN 345 >3CO4-A nrPDB Length = 312 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 69/346 (19%), Positives = 130/346 (37%), Gaps = 87/346 (25%) Query: 46 IDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAP 105 I+ TH+ +FA ++ + + R N +K L+++ K P Sbjct: 24 IEWKYLTHINASFARVKADGTLNINPVRKRIESVRETAHKHN--VKILISLA--KNSPGE 79 Query: 106 FSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKA 165 F+ ++ P+ R+ IQ +I F ++Y DG ++D++ Sbjct: 80 FTTAINDPKARKELIQQIIAFTKEYKLDGFDIDYE------------------------- 114 Query: 166 FEEESVEKDIPRLLLTSTGAGIID--------VIKSGYKI--PELSQSLDYIQVMTYDLH 215 E ++ +K+ P LL+ + G + + S + E Q DYI +M+YD Sbjct: 115 -EYDNWDKNFPSLLVFARGLYLAKEKNMLMTCAVNSRWLNYGTEWEQYFDYINLMSYD-- 171 Query: 216 DPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASE-KLIVGFPAYGHTFILS 274 + +T + P+ + YD D D + YW + AS+ K++ G P YG+++ Sbjct: 172 --RGAFT--DKPVQHASYD-----DFVKD--LKYWNEQCRASKSKIVGGLPFYGYSW--- 217 Query: 275 DPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWV 334 G D G+ + NE A + D + Y + Sbjct: 218 ------------EESLQGAVDDVRGIRYSGILKHLGNEAADK--DNIGKTYYNGRPT--- 260 Query: 335 GYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLT 380 K +++K+N+ G ++W L D H ++ L Sbjct: 261 -------IANKCKFIKENDYAGVMIWQLFQD------AHNDNYDLK 293 >5JH8-A nrPDB Length = 317 Score = 130 bits (327), Expect = 1e-30, Method: Composition-based stats. Identities = 62/278 (22%), Positives = 112/278 (40%), Gaps = 56/278 (20%) Query: 97 GGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFS 156 G W A + VST Q + ++++F + F G+N+D++ D++ FS Sbjct: 74 GNW---SADIAHAVSTSAQSQA-VANLVKFAQDKRFSGINVDFE-----AVAQGDRNNFS 124 Query: 157 VLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVI---KSGYKIPELSQSLDYIQVMTYD 213 ++ + +A + + +L+++ D GY + L + DY+Q+M+YD Sbjct: 125 HFIQVLGRALHAKGL-----KLIVSVPAFSAKDENHPANYGYDLRALGAAADYLQIMSYD 179 Query: 214 LHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFIL 273 P + P+ S + + D V+ + K++ G PAYG+ + Sbjct: 180 EAIP----AWDPGPVAGSDW-MEDDLDYAVER---------VPAAKILNGIPAYGYDWK- 224 Query: 274 SDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDA-PQEVPYAYQGNE 332 + G G + D L+A Y GA +DA + + Y + Sbjct: 225 ----RPGDGGMLY-------WKDTQALIARY--------GAQPRYDAGTHSLTFNYGAAD 265 Query: 333 W----VGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDD 366 V +N RS LKA + LGG ++ L M+D Sbjct: 266 GSRHTVWTENARSVALKASLVNAYGLGGTSLYALGMED 303 >3CZ8-A nrPDB Length = 319 Score = 106 bits (264), Expect = 2e-23, Method: Composition-based stats. Identities = 48/275 (17%), Positives = 96/275 (34%), Gaps = 53/275 (19%) Query: 100 KFGPAPFSA-----MVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHL 154 FS +++ P R + ++ + + G+ +D++ D+ L Sbjct: 75 NLTSGGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGYGGVTIDFE-----QVSAADRDL 129 Query: 155 FSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK--SGYKIPELSQSLDYIQVMTY 212 F+ ++++R + +L + A D I GY + ++Y+ +M Y Sbjct: 130 FTGFLRQLRDRLQA------GGYVLTIAVPAKTSDNIPWLRGYDYGGIGAVVNYMFIMAY 183 Query: 213 DLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFI 272 D ++ P ++ I+ S K+I+G P YG+ +I Sbjct: 184 D---------WHHAGSEPGPVAPITEIRRTIEFTIAQ-----VPSRKIIIGVPLYGYDWI 229 Query: 273 LSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVP-YAYQGN 331 + P + G A IS + + A + A + P + Y Sbjct: 230 I--PYQPGTVASAISNQNA--------------IERAMRYQAPIQYSAEYQSPFFRYSDQ 273 Query: 332 EW----VGYDNVRSFKLKAQWLKDNNLGGAVVWPL 362 + V ++ VRS K Q +++ L W L Sbjct: 274 QGRTHEVWFEGVRSMSRKMQIVREYRLQAIGAWQL 308 >4S3K-A nrPDB Length = 436 Score = 94.3 bits (233), Expect = 7e-20, Method: Composition-based stats. Identities = 49/305 (16%), Positives = 106/305 (34%), Gaps = 49/305 (16%) Query: 90 LKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPP 149 L L I F A+++ + + ++++ ++ NF ++ D+++ P Sbjct: 171 LMVLANIENGAFSDEVGRAILNNKDVQDTLLNNIVKTAKEQNFRDIHFDFEF-----LRP 225 Query: 150 KDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGY----KIPELSQSLD 205 DK + +++ +K ++E L+ + K + + + + Sbjct: 226 ADKEAYIAFLQKAKKRLQDE------QLLMSVALAPKTSRDQKGKWYEAHDYKAIGEIAN 279 Query: 206 YIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFP 265 ++ MTY+ Y + S V ++ Y S K+I+G Sbjct: 280 FVVPMTYE----WG---------YSGGPPMAVSPIGPVRDVLEYAVSE-IPSSKIIMGQN 325 Query: 266 AYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVP 325 YG+ + L P K G G+Y + + +D + P Sbjct: 326 LYGYDWTL--PYKPG-----------GEY--AKAISPQRAIELAARYKVAIQYDNKAQAP 370 Query: 326 Y-AYQG----NEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLT 380 + Y+ V +++ RS + K +K+ L G W L +D + +F +T Sbjct: 371 FFRYKDEQQRTHEVWFEDARSIQAKFDLIKELKLRGMAYWKLGLDFPQNWLLIEDNFKIT 430 Query: 381 STLKG 385 + Sbjct: 431 KRVTQ 435 >4S3J-A nrPDB Length = 433 Score = 93.9 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 54/325 (16%), Positives = 110/325 (33%), Gaps = 47/325 (14%) Query: 46 IDPCLCTHLIY-AFAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPA 104 I+P L T+L Y +F ++ + + + L + I F Sbjct: 129 INPFL-TYLAYFSFEAKRDGTL--KEPTETAKIANIATQGQTIPML-VITNIENGNFSAD 184 Query: 105 PFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRK 164 S ++ + FI ++++ +Y ++ D++ P+D+ ++ +R Sbjct: 185 LTSVILRDATIQNKFITNILQTAEKYGMRDIHFDFE-----SVAPEDREAYNRF---LRN 236 Query: 165 AFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGE 224 + L+ T + + Q +D++ +MTYD G Sbjct: 237 VKIRLPSGYTLSTTLVPKTSSNQKGKFFEAHDYKAQGQIVDFVVIMTYD----WGWQGGP 292 Query: 225 NSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAP 284 P+ SP V ++ Y K +K+++G YG + L P Sbjct: 293 --PMAISPIGP-------VKEVLQYAKSQ-MPPQKIMMGQNLYGFDWKL----------P 332 Query: 285 TISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVP----YAYQGNEW-VGYDNV 339 PP K +A +D + P + G + V +++ Sbjct: 333 FKQGNPPAKAVSSVAAVALAR-----KYNVPIRYDFTAQAPHFNYFDENGVQHEVWFEDA 387 Query: 340 RSFKLKAQWLKDNNLGGAVVWPLDM 364 RS + K +K+ +GG W + + Sbjct: 388 RSIQSKFNLMKEQGIGGISYWKIGL 412 >3BXW-B nrPDB Length = 393 Score = 69.6 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 50/354 (14%), Positives = 117/354 (33%), Gaps = 63/354 (17%) Query: 24 LMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEA--LN 81 ++ Y T W + + T + + ++ L D + + Sbjct: 81 VLGYVTPWNSH-----GYDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQGWMR 135 Query: 82 GLKDKNTELKTLLAI--GGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDW 139 ++ L + + W + F ++ + + ++V++ + +FDG ++ Sbjct: 136 AVRKHAKGLHIVPRLLFEDWTYDD--FRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVE- 192 Query: 140 QYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLT--STGAGIIDVIK-SGYK 196 + + ++ + +A + + LL+ + G + + + Sbjct: 193 ---VWNQLLSQKRVGLIHMLTHLAEALHQ----ARLLALLVIPPAITPGTDQLGMFTHKE 245 Query: 197 IPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAA 256 +L+ LD +MTYD G N+PL A + V S W+ Sbjct: 246 FEQLAPVLDGFSLMTYDYSTA--HQPGPNAPL------SWVRACVQVLDPKSKWR----- 292 Query: 257 SEKLIVGFPAYGHTF-ILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGAT 315 K+++G YG + D + +GA + T + Sbjct: 293 -SKILLGLNFYGMDYATSKDAREPVVGARY--------------------IQTLKDHRPR 331 Query: 316 EVWDAPQEVPY-----AYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDM 364 VWD+ + + G V Y ++S +++ + ++ + G +W L Sbjct: 332 MVWDSQASEHFFEYKKSRSGRHVVFYPTLKSLQVRLELARELGV-GVSIWELGQ 384 >3IAN-A nrPDB Length = 321 Score = 60.8 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 39/256 (15%), Positives = 83/256 (32%), Gaps = 30/256 (11%) Query: 24 LMCYYTSW-AKDRPIEGSFKPGNIDPCLCTH----LIYAFAGMQNNEITYTHEQD-LRDY 77 L+ Y+ +W + + + + + +F + T + D Sbjct: 7 LVGYWHNWKSTGKDGYKGGSSADFNLSSTQEGYNVINVSFMKTPEGQTLPTFKPYNKTDT 66 Query: 78 EALNGLKDKNTELK-TLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLN 136 E + N E K L+A+GG + + F+ +IR + Y FDGL+ Sbjct: 67 EFRAEISKLNAEGKSVLIALGGAD------AHIELKKSQESDFVNEIIRLVDTYGFDGLD 120 Query: 137 LDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTST-GAGIIDVIKSGY 195 +D + + ++ K ++ + ++ + + K Sbjct: 121 IDLE------QAAIEAADNQTVIPSALKKVKDHYRKDGKNFMITMAPEFPYLTSSGKYAP 174 Query: 196 KIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHG- 254 I L D+I Y+ DG+ + ++ S + K D ++ G Sbjct: 175 YINNLDSYYDFINPQYYNQGG--DGFWDSDLNMWISQSNDEKKEDFL--YGLTQRLVTGT 230 Query: 255 -----AASEKLIVGFP 265 + K ++G P Sbjct: 231 DGFIKIPASKFVIGLP 246 >4RL3-A nrPDB Length = 272 Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 32/226 (14%), Positives = 78/226 (34%), Gaps = 26/226 (11%) Query: 46 IDPCLCTHLIYAFA-------GMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 98 I+ + H I AFA N + + A+ +K +++ +K ++++GG Sbjct: 22 INSGVTFHFILAFAIDYTSAAAATNGVFNIYWQNSVLTPAAVQAIKAQHSNVKVMVSLGG 81 Query: 99 WKFGPAPF-SAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSV 157 +P S + S+ + QY+ DG+++D+++ + F Sbjct: 82 DTISGSPVQFTATSVSSWVANAVSSLTSLINQYHLDGIDIDYEHFDQVSTS-----TFVS 136 Query: 158 LVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDP 217 + ++ + +V + S + + S +D + Y Sbjct: 137 CIGQLITQLKANNVIS------VASIAPFDGVESQYTALFGQYSSVIDLVNFQFYSYG-- 188 Query: 218 KDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGA-ASEKLIV 262 G ++ Y S Y+ S +++ + G + ++ Sbjct: 189 ----AGTSASQYVSLYNTAASKYGGGAKVLASFSTGGVGPAPSTVL 230 >3SIM-A nrPDB Length = 275 Score = 58.1 bits (139), Expect = 6e-09, Method: Composition-based stats. Identities = 23/168 (13%), Positives = 64/168 (38%), Gaps = 18/168 (10%) Query: 62 QNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQN-RQIFI 120 N + + + + ++ +K + ++ +++GG G ++ + + Sbjct: 48 TNGKFNVFWDSSILGPDQISAIKSSHPNVRVAVSLGGASVGSNTVQFQAASVDSWVSNAV 107 Query: 121 QSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLL 180 S+ R +++YN DG+++D+++ DK+ F+ + + ++ V + Sbjct: 108 TSLTRIIQRYNLDGIDIDYEH-----FQNTDKNTFAECIGRLITTLKKNGV--------I 154 Query: 181 TSTGAGIIDVIKSGY--KIPELSQSLDYIQVM--TYDLHDPKDGYTGE 224 + + Y E ++++I YD D + G Sbjct: 155 SFASISPFPSVDEYYLALFNEYKNAINHINYQFKAYDSSTSVDKFLGY 202 >3EBV-A nrPDB Length = 302 Score = 56.2 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 43/243 (17%), Positives = 84/243 (34%), Gaps = 41/243 (16%) Query: 91 KTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPK 150 K ++++GG K + V++ + F SV +R+Y FDG+++D + G P Sbjct: 77 KVIISVGGEKGTVS-----VNSSASATNFANSVYSVMREYGFDGVDIDLE----NGLNPT 127 Query: 151 DKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS--QSLDYIQ 208 M +A S + +L + + + GY L+ L + Sbjct: 128 ----------YMTQALRALSAKAGPDMILTMAPQTIDMQSTQGGYFQTALNVKDILTVVN 177 Query: 209 VMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYG 268 M Y G + +Y G L + I + G A ++ +G PA Sbjct: 178 -MQY---YNSGTMLGCDGKVYA----QGTVDFLTALACIQ--LEGGLAPSQVGLGLPAST 227 Query: 269 HTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLN----EGATEVWDAPQEV 324 + G +P++ T + ++ T+ + + WDA Sbjct: 228 RA------AGGGYVSPSVVNAALDCLTKATNCGSFKPSKTYPDLRGAMTWSTNWDATAGN 281 Query: 325 PYA 327 ++ Sbjct: 282 AWS 284 >4TX8-A nrPDB Length = 439 Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 52/279 (18%), Positives = 94/279 (33%), Gaps = 49/279 (17%) Query: 20 SSYQLMCYYTSWAKDRPIEGSFKPGNI--DPCLCTHLIYAFAG-MQNNEITYTHEQDLR- 75 + + L+ Y+ ++A P +F + D + ++ AFA N +++T + Sbjct: 105 AKHALVGYWHNFAN--PSGSAFPLSQVSADWDV---IVVAFADDAGNGNVSFTLDPAAGS 159 Query: 76 ---DYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNF 132 + + + K K +L++GG ++ Q F+ S+ L QY F Sbjct: 160 AAQFIQDIRAQQAKGK--KVVLSLGGQNGSVT-----LNNATQVQNFVNSLYGILTQYGF 212 Query: 133 DGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIK 192 DG++LD + VK+++ P G Sbjct: 213 DGIDLDLESGSGIVVGAPVVSNLVSAVKQLKAKIGPNFYLSMAPEHPYVQGGFVAYGGNW 272 Query: 193 SGYK--IPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSII--S 248 Y I L L I V Y+ N LY +PY G A+ + D ++ S Sbjct: 273 GAYLPIIDGLRDDLSVIHVQYYN-----------NGGLY-TPYSTGVLAEGSADMLVGGS 320 Query: 249 YWKDHGAA-------------SEKLIVGFPAYGHTFILS 274 G +++ G P+ G + S Sbjct: 321 KMLIEGFPIANGASGSFKGLRPDQVAFGVPS-GRSSANS 358 >1NAR-A nrPDB Length = 290 Score = 51.9 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 31/210 (14%), Positives = 74/210 (35%), Gaps = 44/210 (20%) Query: 53 HLIYAFA-------GMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAP 105 H I FA G + + +L E + LK ++ E+K +++IGG + P Sbjct: 34 HYILGFAIESYYESGKGTGTFEESWDVELFGPEKVKNLKRRHPEVKVVISIGG-RGVNTP 92 Query: 106 FSAMVSTPQNRQIFIQSVIR----FLRQYN------FDGLNLDWQYPGSRGSPPKDKHLF 155 F P +++ + +++Y+ DG+++ +++ S F Sbjct: 93 F-----DPAEENVWVSNAKESLKLIIQKYSDDSGNLIDGIDIHYEHIRSD-------EPF 140 Query: 156 SVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLH 215 + L+ ++ +++ + ++ + + Y + DYI + Y Sbjct: 141 ATLMGQLITELKKD--DDLNINVVSIAPSENNSSHYQKLYNAKK-----DYINWVDYQF- 192 Query: 216 DPKDGYTGENSPLYKSPYDIGKSADLNVDS 245 + + P+ + L D Sbjct: 193 ------SNQQKPVSTDDAFVEIFKSLEKDY 216 >4W5Z-A nrPDB Length = 345 Score = 51.5 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 40/258 (15%), Positives = 82/258 (31%), Gaps = 32/258 (12%) Query: 24 LMCYYTSWAKDRPIEG-------------SFKPGNIDPCLCTHLIYAFAGMQNNEITYTH 70 ++ Y+ +W R +G + NI + A + ++ T Sbjct: 33 VVGYWHNWCDGRGYQGGNAPCVELKTVNPQYNVVNISFMKVYDI--AEGRIPTFKLDPTI 90 Query: 71 E-QDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQ 129 + ++ L + L+A+GG + + T + +IR Sbjct: 91 ALSEAEFIAQIDTLNSQGRS--VLIALGGAD------AHIELTRGDEDALAAEIIRLTDL 142 Query: 130 YNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIID 189 Y FDGL++D + KD ++ K +E + ++ + + Sbjct: 143 YGFDGLDIDLE---QAAITAKDNQF---VIPAALKMVKEHYRKTGDNFMITMAPEFPYLT 196 Query: 190 VIKSGYKI-PELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIIS 248 + EL D+I Y+ G + + DS+I+ Sbjct: 197 ANGAYTPYLTELDGYYDFINPQFYNQGGDGLWIEGVGWIAQNNDALKEEFIYYIADSLIN 256 Query: 249 YWKD-HGAASEKLIVGFP 265 ++ H +KL+ G P Sbjct: 257 GTRNYHKIPHDKLVFGLP 274 >2Y8V-A nrPDB Length = 290 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 38/248 (15%), Positives = 81/248 (32%), Gaps = 38/248 (15%) Query: 22 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 81 +++CY+ + +R S P + TH+I A + + T D D+E N Sbjct: 13 RRVICYHQTLCPNRGDYVSVLPLVKNNTGVTHIIIAAFHLNEDPGHITLNDDPPDHEMYN 72 Query: 82 GLKD-----KNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLN 136 L K + +K + +GG G + + + + + Q ++ +R++ DGL+ Sbjct: 73 PLWAEVPVLKRSGVKVMGMLGGAAQGS--YRCLDGDQEKFERYYQPLLAMVRRHQLDGLD 130 Query: 137 LDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYK 196 LD + L+ ++ ++ + L A + SG+ Sbjct: 131 LDVE-------EEMSLPGIIRLIDRLKLDLGDDFIIT-----LAPVAAALLGIGNLSGFD 178 Query: 197 IPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAA 256 +L Q + N+ Y G + Sbjct: 179 YRQLEQQ-------------RGSKISWYNAQFYNGWGLAEDPRMYAA------IVAQGWS 219 Query: 257 SEKLIVGF 264 ++++ G Sbjct: 220 PQRVVYGL 227 >4MB4-A nrPDB Length = 528 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 41/258 (15%), Positives = 82/258 (31%), Gaps = 32/258 (12%) Query: 24 LMCYYTSWAKDRPIEG-------------SFKPGNIDPCLCTHLIYAFAGMQNNEITYTH 70 ++ Y+ +W R +G + NI + A + ++ T Sbjct: 11 VVGYWHNWCDGRGYQGGNAPCVELKTVNPQYNVVNISFMKVYDI--AEGRIPTFKLDPTI 68 Query: 71 E-QDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQ 129 + ++ L + L+A+GG + + T + +IR Sbjct: 69 ALSEAEFIAQIDTLNSQGRS--VLIALGGAD------AHIELTRGDEDALAAEIIRLTDL 120 Query: 130 YNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIID 189 Y FDGL++D Q KD ++ K +E + ++ + + Sbjct: 121 YGFDGLDIDLQ---QAAITAKDNQF---VIPAALKMVKEHYRKTGDNFMITMAPEFPYLT 174 Query: 190 VIKSGYKI-PELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIIS 248 + EL D+I Y+ G + + DS+I+ Sbjct: 175 ANGAYTPYLTELDGYYDFINPQFYNQGGDGLWIEGVGWIAQNNDALKEEFIYYIADSLIN 234 Query: 249 YWKD-HGAASEKLIVGFP 265 ++ H +KL+ G P Sbjct: 235 GTRNYHKIPHDKLVFGLP 252 >3N18-A nrPDB Length = 333 Score = 48.1 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 15/119 (12%) Query: 24 LMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQ----DLRDYEA 79 L+ Y W G K ++ P + +F + T D Sbjct: 9 LVGY---WHNFDNGTGIIKLKDVSPKWDV-INVSFGETGGDRSTVEFSPVYGTDADFKSD 64 Query: 80 LNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLD 138 ++ LK K K +L+IGG ++ + FI S+ + +Y FDG+++D Sbjct: 65 ISYLKSKGK--KVVLSIGG-----QNGVVLLPDNAAKDRFINSIQSLIDKYGFDGIDID 116 >4AXN-A nrPDB Length = 328 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 38/250 (15%), Positives = 85/250 (34%), Gaps = 21/250 (8%) Query: 24 LMCYYTSWAKDRPIE---GSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEAL 80 LM ++ +WA G F N+ + + A A M+ I +L D E Sbjct: 27 LMGFWHNWAAGASDGYQQGQFANMNLTDIPTEYNVVAVAFMKGQGIPTFKPYNLSDTEFR 86 Query: 81 NGLKDKNTELK-TLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDW 139 + N++ + L+++GG + + + +IR + Y FDGL++D Sbjct: 87 RQVGVLNSQGRAVLISLGGAD------AHIELKTGDEDKLKDEIIRLVEVYGFDGLDIDL 140 Query: 140 QYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYK-IP 198 + + + +VL ++K + + + ++ + + + I Sbjct: 141 E-----QAAIGAANNKTVLPAALKKVKDHYAAQ-GKNFIISMAPEFPYLRTNGTYLDYIN 194 Query: 199 ELSQSLDYIQVMTYDL--HDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKD-HGA 255 L D+I Y+ + +S+++ + Sbjct: 195 ALEGYYDFIAPQYYNQGGDGIWVDELNA-WITQNNDAMKEDFLYYLTESLVTGTRGYAKI 253 Query: 256 ASEKLIVGFP 265 + K ++G P Sbjct: 254 PAAKFVIGLP 263 >1EDT-A nrPDB Length = 271 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 65/183 (35%), Gaps = 23/183 (12%) Query: 77 YEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLN 136 + L+ + +K LL++ G A F+ S F + + + +Y DG++ Sbjct: 73 VTQIRPLQQQ--GIKVLLSVLG-NHQGAGFANFPSQQAA-SAFAKQLSDAVAKYGLDGVD 128 Query: 137 LDWQYP--GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSG 194 D +Y G+ G+ + F LV +R ++ + L + G + G Sbjct: 129 FDDEYAEYGNNGTAQPNDSSFVHLVTALRANMPDKIIS-------LYNIGPAASRLSYGG 181 Query: 195 YKIPELSQSLDY-IQVMTYDLHDPK--DGYTGENSPLYKSPYDIGKSADLNVDSIISYWK 251 + S DY + G + L + +IG+++ V + Sbjct: 182 VDV---SDKFDYAWN----PYYGTWQVPGIALPKAQLSPAAVEIGRTSRSTVADLARRTV 234 Query: 252 DHG 254 D G Sbjct: 235 DEG 237 >2EBN-A nrPDB Length = 289 Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 60/180 (33%), Gaps = 24/180 (13%) Query: 54 LIYAFAGMQNNEITYTHEQDLRDY-----EALNGLKDKNTELKTLLAIGGWKFGPAPFSA 108 + Y A N+++ ++ +++ + L L+DK +K +L+I G S Sbjct: 49 INYDAA---NDKVFVSNNPNVQHLLTNRAKYLKPLQDK--GIKVILSI----LGNHDRSG 99 Query: 109 MVSTPQNR-QIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFE 167 + + R + F Q + YN DG+ D +Y + PP F Sbjct: 100 IANLSTARAKAFAQELKNTCDLYNLDGVFFDDEYSAYQTPPPS---GFVTPSNNAAARL- 155 Query: 168 EESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDY-IQVMTYDLHDPKDGYTGENS 226 ++ +P L+T + +DY I D D T Sbjct: 156 AYETKQAMPNKLVTVYVYSRTSSFPTAVDGVNAGSYVDYAIH----DYGGSYDLATNYPG 211 >4GUW-A nrPDB Length = 246 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 45/122 (36%), Gaps = 6/122 (4%) Query: 150 KDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAG-IIDVIKSGYKIPELSQSLD--Y 206 D + + +K++R A +IP LL + +GAG + + Y ++ ++D Sbjct: 9 ADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLMHLFNYDGNTITVAVDVTN 68 Query: 207 IQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISY---WKDHGAASEKLIVG 263 + +M Y + + L + + +Y G EK+ +G Sbjct: 69 VYIMGYLALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYERLQIAAGKPREKIPIG 128 Query: 264 FP 265 P Sbjct: 129 LP 130 >1F8Q-A nrPDB Length = 263 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 47/124 (37%), Gaps = 10/124 (8%) Query: 150 KDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAG-IIDVIKSGYKIPELSQSLD--Y 206 D + + +K++R A +IP LL + +GAG + + ++ ++D Sbjct: 9 ADPRSYGMFIKDLRNALPFREKVYNIPLLLPSVSGAGRYLLMHLFNRDGKTITVAVDVTN 68 Query: 207 IQVMTYDLHDPKDGYTGENSPLYKSPYD-----IGKSADLNVDSIISYWKDHGAASEKLI 261 + +M Y L D + E + S Y + + D G EK+ Sbjct: 69 VYIMGY-LADTTSYFFNEPAAELASQYVFRDARRKITLPYSGDYE-RLQIAAGKPREKIP 126 Query: 262 VGFP 265 +G P Sbjct: 127 IGLP 130 >6MDV-A nrPDB Length = 802 Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 44/351 (12%), Positives = 106/351 (30%), Gaps = 61/351 (17%) Query: 1 MAKLILVTGLAILLNVQLGSSYQL-MCYYTSW----AKDRPIEGSFK-------PGNIDP 48 M K G ++ ++ G L Y+ +W + + P +D Sbjct: 1 MGKTDQQVGAKLVQEIREGKRGPLYAGYFRTWHDRASTGIDGKQQHPENTMAEVPKEVD- 59 Query: 49 CLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSA 108 +++ F ++ + E ++ L + T L + + Sbjct: 60 -----ILFVFHDHTASDSPFWSELKDS---YVHKLHQQGTALVQTIGVNELNGRTGLSKD 111 Query: 109 MVSTPQNRQIFIQSVIR-FLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFE 167 TP+ + ++++ F+ DGL++D ++ + P++ + KE+ + Sbjct: 112 YPDTPEGNKALAAAIVKAFVTDRGVDGLDIDIEHEFTNKRTPEEDARALNVFKEIAQLIG 171 Query: 168 EESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSP 227 + +K ++ T+ + +++ LDY+ Y G G + Sbjct: 172 KNGSDKSKLLIMDTTLSVENNPI------FKGIAEDLDYLLRQYY-------GSQGGEAE 218 Query: 228 LYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAY------GHTFILSDPSKTGI 281 + D + + + + ++GF + G+ + + Sbjct: 219 VDTINSDWNQYQNY-------------IDASQFMIGFSFFEESASKGNLWFDVNEYDPNN 265 Query: 282 GAPTISTGPPGKYTDESGLLAYYEVCTFLNEG---ATEVWDAPQEVPYAYQ 329 G + T + L G D VP Y+ Sbjct: 266 P----EKGKDIEGTRAKKYAEWQPSTGGLKAGIFSYAIDRDGVAHVPSTYK 312 >4NUY-A nrPDB Length = 899 Score = 33.8 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 48/295 (16%), Positives = 99/295 (33%), Gaps = 57/295 (19%) Query: 26 CYYTSW--------AKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDY 77 Y+ +W KD+ P +D H + + E + Sbjct: 19 GYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFH------DWTKDYSLFWKELATKHV 72 Query: 78 EALNGLKDKNTELKTLLAIGGWKFGPAP--------FSAMVSTPQNRQIFIQSVIR-FLR 128 LN K ++T+ W+F S +TP+ + ++++ ++ Sbjct: 73 PKLN--KQGTRVIRTIP----WRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVDEYVY 126 Query: 129 QYNFDGLNLDWQY---PG-SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTG 184 +YN DGL++D ++ P + + +E+ K + V+K ++ ++ Sbjct: 127 KYNLDGLDVDVEHDSIPKVDKKEDTAGVERSIQVFEEIGKLIGPKGVDKSRLFIMDSTYM 186 Query: 185 AGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVD 244 A +I+ G YI ++ ++ G G P+ P + Sbjct: 187 ADKNPLIERGAP---------YINLLLVQVYGS-QGEKGGWEPVSNRPEKTMEERW---- 232 Query: 245 SIISYWKDHGAASEKLIVGFPAY------GHTFILSDPSKTGIGAPTISTGPPGK 293 S + E+ ++GF Y G+ + + K A I+T G Sbjct: 233 QGYSKYIR----PEQYMIGFSFYEENAQEGNLWYDINSRKDEDKANGINTDITGT 283 >4TOQ-A nrPDB Length = 273 Score = 32.7 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 61/192 (31%), Gaps = 50/192 (26%) Query: 86 KNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFI----------QSVIRFLRQYNFDGL 135 + ++K L++IGG G +S +VS F QS R L DG+ Sbjct: 68 QGKDIKVLMSIGG---GAGDYS-LVSEADA-DNFADYLWNNFLGGQSSSRPLGDAVLDGI 122 Query: 136 NLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGY 195 + D + + + +A S + L T A S Sbjct: 123 DFDIEL------------GTTTFYDTLARALSSRSTQAAKVYL----TAAPQCPHPDSHL 166 Query: 196 KIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWK--DH 253 + D + + Y N+PL + Y G N + I+S W Sbjct: 167 DAALNTGLFDNVWIQFY------------NNPLAQCQYSSG-----NTNDILSSWNTWTS 209 Query: 254 GAASEKLIVGFP 265 + K+ +G P Sbjct: 210 STTAGKIFLGLP 221 >6Q64-A nrPDB Length = 364 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 31/171 (18%), Positives = 52/171 (30%), Gaps = 24/171 (14%) Query: 117 QIFIQSVIRFLRQYNFDGLNLDWQYPGSRGS---------PPKDKHLFSVLVKEMRKAFE 167 + + ++ + +YN DG ++D+Q PG S P + V ++ + Sbjct: 167 KAYANAICDSIEKYNLDGFDIDYQ-PGYGHSGTLANYQTISPSGNNKMQVFIETLSARLR 225 Query: 168 EES---VEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGE 224 V P LL T T + I Y S + I D + T Sbjct: 226 PAGRMLVMDGQPDLLSTETSKLVDHYIYQAYWESSTSSVIYKINKPNLD---DWERKTII 282 Query: 225 NSPLYKSPYDIGKSADLNV--------DSIISYWKDHGAASEKLIVGFPAY 267 + G + +V + I + S K I G Y Sbjct: 283 TVEFEQGWKTGGITYYTSVRPELNSMEGNQILDYATLDLPSGKRIGGIGTY 333 >2XVP-A nrPDB Length = 310 Score = 31.9 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 60/192 (31%), Gaps = 50/192 (26%) Query: 91 KTLLAIGG-----------------WKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFD 133 K LL+IGG F F + + + F V+ D Sbjct: 89 KVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVV--------D 140 Query: 134 GLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKS 193 G + D ++ G G ++ +V R+ F + + L++ II Sbjct: 141 GFDFDIEHNGGFG--------YATMVNTFRQYFN----QVPERKFYLSAAPQCIIPD--- 185 Query: 194 GYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDH 253 +Q D I +D Y + KS D N D+ ++ K Sbjct: 186 -------AQLSDAIFNAAFDF--IWIQYYNTAACSAKSFIDTSLGT-FNFDAWVTVLKAS 235 Query: 254 GAASEKLIVGFP 265 + KL VG P Sbjct: 236 ASKDAKLYVGLP 247 >4AEF-A nrPDB Length = 645 Score = 31.9 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 25/93 (26%) Query: 84 KDKNTELKTLLAIGGWKFGPAPFSAM-------VSTPQNRQIFIQSVIRFLRQYNFDGLN 136 ++K ++K+L GW + F ++ P+ R+ FI++VI F DG Sbjct: 357 EEKYKKIKSL----GWNYES--FFSVWIMPRLNHDNPKVRE-FIKNVILFWTNKGVDGFR 409 Query: 137 LDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEE 169 +D + G PP+ + KE+R+A +E Sbjct: 410 MD----VAHGVPPE-------VWKEVREALPKE 431 >2GSJ-A nrPDB Length = 271 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 28/182 (15%), Positives = 64/182 (35%), Gaps = 39/182 (21%) Query: 86 KNTELKTLLAIGGWKFGPAPFSAMVSTPQNR-------QIFI--QSVIRFLRQYNFDGLN 136 + +K +L+IGG G +S + S R F+ +S R L DG++ Sbjct: 68 QRRGIKVMLSIGG---GAGSYS-LSSVQDARSVADYIWNNFLGGRSSSRPLGDAVLDGVD 123 Query: 137 LDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYK 196 D ++ G+ + L + + + + ++ L++ Sbjct: 124 FDIEHGGAY---------YDALARRLSE------HNRGGKKVFLSAAPQCPF--PDQSLN 166 Query: 197 IPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAA 256 + DY+ V Y+ + + +G S +++ ++ S+ N + G Sbjct: 167 KALSTGLFDYVWVQFYN-NPQCEFNSGNPSN-FRNSWNKWTSS-FNAKFYV------GLP 217 Query: 257 SE 258 + Sbjct: 218 AS 219 >3Q6J-A nrPDB Length = 523 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 30/88 (34%), Gaps = 11/88 (12%) Query: 40 SFKPGNIDPCLCTHLIYAFAGMQNNE--------ITYTHEQDLRDYEALNGLKDKNTELK 91 S+ P N L TH +F GM E +T D + L + + Sbjct: 381 SYTPKNYPDFLHTHYEVSFLGMGEEEARAAGHEIVTIKMPPDTEN-GLNVALPASDRTM- 438 Query: 92 TLLAIGGWKFGPAPFSAMVSTPQNRQIF 119 L A G + F +V + R++ Sbjct: 439 -LYAFGKGTAHMSGFQKIVIDAKTRKVL 465 >4KVF-A nrPDB Length = 342 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 18/37 (48%) Query: 59 AGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLA 95 A ++ +I Y ++ D + + GL LK +++ Sbjct: 195 AKLKLVKIAYGNDDDQKSFTEAQGLLQSYPNLKVIVS 231 >4WM7-C nrPDB Length = 247 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 25/86 (29%), Gaps = 23/86 (26%) Query: 27 YYTSWAK---------------------DRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNE 65 YYT W+ P GS L TH+++ F G+Q++ Sbjct: 105 YYTHWSGSLEMTFMFCGSFMATGKLILCYTPPGGSCPTTRETAMLGTHIVWDF-GLQSSI 163 Query: 66 ITYTHEQDLRDYEALNG-LKDKNTEL 90 Y N K N + Sbjct: 164 TLIIPWISGSHYRMFNSDAKSTNANV 189 >1R8K-A nrPDB Length = 329 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 19/53 (35%), Gaps = 14/53 (26%) Query: 225 NSPLYKSPYDIGKSADL--NVDSIISYWKDHGAASEK---------LIVGFPA 266 N PL P D N D++++ + D G K + +G P Sbjct: 241 NGPL---PADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPF 290 >1PTM-A nrPDB Length = 329 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 19/53 (35%), Gaps = 14/53 (26%) Query: 225 NSPLYKSPYDIGKSADL--NVDSIISYWKDHGAASEK---------LIVGFPA 266 N PL P D N D++++ + D G K + +G P Sbjct: 241 NGPL---PADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPF 290 >3V6B-R nrPDB Length = 424 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 25/67 (37%), Gaps = 5/67 (7%) Query: 134 GLNLDWQYPGSRG-----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 G++ +W+YP S+ K +K+ + V + L + +G++ Sbjct: 125 GIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLM 184 Query: 189 DVIKSGY 195 S + Sbjct: 185 TKKNSTF 191 >3V2A-R nrPDB Length = 772 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 25/67 (37%), Gaps = 5/67 (7%) Query: 134 GLNLDWQYPGSRG-----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 G++ +W+YP S+ K +K+ + V + L + +G++ Sbjct: 255 GIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLM 314 Query: 189 DVIKSGY 195 S + Sbjct: 315 TKKNSTF 321 >3S35-X nrPDB Length = 122 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 25/67 (37%), Gaps = 5/67 (7%) Query: 134 GLNLDWQYPGSRG-----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 G++ +W+YP S+ K +K+ + V + L + +G++ Sbjct: 39 GIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLM 98 Query: 189 DVIKSGY 195 S + Sbjct: 99 TKKNSTF 105 >2X1X-R nrPDB Length = 213 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 25/67 (37%), Gaps = 5/67 (7%) Query: 134 GLNLDWQYPGSRG-----SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGII 188 G++ +W+YP S+ K +K+ + V + L + +G++ Sbjct: 136 GIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLM 195 Query: 189 DVIKSGY 195 S + Sbjct: 196 TKKNSTF 202 >2PZM-A nrPDB Length = 330 Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 4/69 (5%) Query: 224 ENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPA---YGHTFILSDPSKTG 280 ++ YK P D + A NV I+ K A K ++ F YG + P Sbjct: 94 HSAAAYKDPDDWAEDAATNVQGSINVAKAASKAGVKRLLNFQTALCYGRPATVPIP-IDS 152 Query: 281 IGAPTISTG 289 AP S G Sbjct: 153 PTAPFTSYG 161 >3U0W-H nrPDB Length = 216 Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 26/68 (38%), Gaps = 2/68 (2%) Query: 18 LGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDY 77 S + Y+ +W + P +G G I+P T + Y +++ I Y Sbjct: 23 AASGFDFSRYWMNWVRQAPGKGLEWIGEINPDSST-INYT-PSLKDKFIISRDNAKNTLY 80 Query: 78 EALNGLKD 85 ++ ++ Sbjct: 81 LQMSKVRS 88 >3MU7-A nrPDB Length = 273 Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 58 FAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 98 F G Q + + + + KN +K LL+IGG Sbjct: 38 FGGGQTPALDISGHSPKGLEPQIKHCQSKN--VKVLLSIGG 76 >2NYA-A nrPDB Length = 792 Score = 29.2 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 29/85 (34%), Gaps = 11/85 (12%) Query: 60 GMQNNEITYTHEQ--DLRDYEALNGLKDKNTELKTLLAIGGWK---------FGPAPFSA 108 + T +Q D+ + + LK+K E + G W A F + Sbjct: 74 DKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRS 133 Query: 109 MVSTPQNRQIFIQSVIRFLRQYNFD 133 P R +V+ F+R + D Sbjct: 134 NNIDPNARHCMASAVVGFMRTFGMD 158 >6FTI-5 nrPDB Length = 705 Score = 28.4 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 40/144 (27%), Gaps = 18/144 (12%) Query: 187 IIDVIKSGYKIPELSQS----LDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLN 242 S Y I S + ++TY H +SP G + + Sbjct: 442 SKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRII 501 Query: 243 VDSI--ISYWKDHGAASEKLIVGFPAYGHTFI-------LSDPSKTGIGAPTISTGPPGK 293 D YW H + ++ + YG+ L D + G Sbjct: 502 FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNN-THISRVGQAMA 560 Query: 294 YTDESGLLAYYEVCTFLNEGATEV 317 T+E YE+ L+ V Sbjct: 561 STEEKA----YEIMRELDVSYVLV 580 >3NJT-A nrPDB Length = 566 Score = 28.0 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 23/160 (14%), Positives = 50/160 (31%), Gaps = 16/160 (10%) Query: 147 SPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPEL---SQS 203 + P D +LVK + A + I + G++ + +I + Sbjct: 98 NRPLDNEQLFLLVKALSAALYDRGYATSIVTFVPPGVVDGVLKLKVEWGRIKGWLIDGKP 157 Query: 204 LDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVG 263 L+ +D ++ + ++D I + G IV Sbjct: 158 LE----------GTRDRMMVFSA---MPGWQDKVLNVFDIDQAIYNINNGGKTGNITIVP 204 Query: 264 FPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAY 303 YG++++ + + ++ G T E+G Y Sbjct: 205 ADEYGYSYLDLQLQRRALPRVSLGMDNSGPGTPENGRYKY 244 >3D5H-A nrPDB Length = 272 Score = 28.0 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 58 FAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGG 98 F G Q + + + + KN +K LL+IGG Sbjct: 38 FGGGQTPALDISGHSPSGLEPQIKHCQSKN--VKVLLSIGG 76 >2WOQ-A nrPDB Length = 337 Score = 28.0 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 20/69 (28%), Gaps = 9/69 (13%) Query: 207 IQVMTYD------LHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYW---KDHGAAS 257 +++M Y + P G S L K + N D + GA Sbjct: 197 VRIMAYSAKYASAYYGPFRDAVGSASNLGKGNKATYQMDPANSDEALHEVAADLAEGADM 256 Query: 258 EKLIVGFPA 266 + G P Sbjct: 257 VMVKPGMPY 265 >1V5D-A nrPDB Length = 386 Score = 27.7 bits (60), Expect = 9.0, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 54/183 (29%), Gaps = 21/183 (11%) Query: 133 DGLNLDWQYPGSRGSPPKDKHLFSVLVKE----MRKAFEEESVEKDIPRLLLTSTGAGII 188 DG +LD Y + +KE + K + +V + L + Sbjct: 135 DG-DLDIAYSLLLAHKQWGSNGTVNYLKEAQDMITKGIKASNVTNNNQLNLGDWDSKSSL 193 Query: 189 DVIKSGYKIPELSQSLDY---------IQVMTYDLHDPKDGYTGENSPLY------KSPY 233 D S + + L ++ I + YD++ N+ L P Sbjct: 194 DTRPSDWMMSHLRAFYEFTGDKTWLTVINNL-YDVYTQFSNKYSPNTGLISDFVVKNPPQ 252 Query: 234 DIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGK 293 K + +Y+ + ++++ + YG K + G P K Sbjct: 253 PAPKDFLDESEYTNAYYYNASRVPLRIVMDYAMYGEKRSKVISDKVSSWIQNKTNGNPSK 312 Query: 294 YTD 296 D Sbjct: 313 IVD 315 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.140 0.418 Lambda K H 0.267 0.0432 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,344,093 Number of Sequences: 36641 Number of extensions: 755636 Number of successful extensions: 2568 Number of sequences better than 10.0: 93 Number of HSP's better than 10.0 without gapping: 111 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 1992 Number of HSP's gapped (non-prelim): 202 length of query: 398 length of database: 10,336,785 effective HSP length: 99 effective length of query: 299 effective length of database: 6,709,326 effective search space: 2006088474 effective search space used: 2006088474 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.6 bits)